Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ADSL ENSG00000239900 "Adenylosuccinate lyase" P30566 22 40346461-40390463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Lyase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 345.1;tongue: 242.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000525, CAB019285" Enhanced Enhanced Cytosol NA NA 440000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB019285: , HPA000525: AB_1078106" "unprognostic (2.80e-1)" "unprognostic (2.12e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.64e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" "prognostic unfavorable (5.81e-8)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (3.99e-1)" "unprognostic (6.28e-2)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (8.43e-2)" "unprognostic (2.70e-1)" "unprognostic (4.06e-1)" "unprognostic (1.44e-2)" 29.8 33.9 10.6 31.1 11.2 40.6 33.1 12.5 13.3 30.7 12.9 36.5 22.7 34.9 21.9 29.8 33.5 20.6 47.4 10.9 10.6 33.6 32.1 22.7 46.9 10.5 11.7 33.5 45.2 29.3 22.0 30.2 10.9 23.8 35.4 10.3 25.7 22.3 345.1 22.2 28.8 41.1 10.0 33.5 28.0 29.2 10.5 50.5 29.6 242.3 48.5 36.0 25.2 10.8 98.0 110.2 88.3 124.9 62.6 89.5 106.5 82.0 85.2 187.3 138.1 189.0 51.9 279.0 73.2 102.3 84.9 67.3 203.5 137.4 187.7 75.3 197.5 126.5 98.4 166.5 134.6 423.0 96.3 97.7 76.5 161.5 169.8 91.3 138.9 127.3 153.1 114.3 136.4 105.0 130.2 131.2 152.5 121.3 119.3 195.1 203.6 198.2 118.9 67.8 58.8 54.4 106.2 54.1 170.7 78.5 76.8 134.7 91.2 93.3 173.7 85.3 168.8 109.0 212.6 218.2 80.9 149.5 97.7 29.0 47.2 19.9 35.5 55.2 49.5 34.6 76.1 48.5 68.1 33.5 58.3 45.0 4.1 48.2 49.7 34.4 81.7 62.3 10.6 11.2 12.5 13.3 10.9 10.6 10.5 11.7 10.9 10.0 10.5 10.8 10.0 12.8 10.8 9.4 28.3 18.1 18.8 48.6 23.9 16.1 14.8 15.0 30.0 30.0 20.8 3.7 37.5 85.3 15.5 13.0 7.9 61.3 44.0 5.6 9.2 21.6 13.8 54.6 11.4 43.7 78.9 21.2 21.4 5.6 36.8 8.8 28.9 25.6 60.3 6.7 10.7 24.1 24.4 44.8 26.7 25.2 24.8 22.7 12.4 1.0 41.9 45.1 19.6 9.5 9.8 33.7 15.6 14.3 52.4 21.3 21.4 19.7 12.3 18.1 26.3 38.5 20.8 61.2 82.8 35.7 15.2 33.1 32.2 8.7 37.7 14.1 ALG10 "ALG10A, DIE2, FLJ14751" ENSG00000139133 "ALG10 alpha-1,2-glucosyltransferase" Q5BKT4 12 34022468-34029694 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA043329: AB_2678432, HPA063387: AB_2685000" "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (3.16e-3)" "unprognostic (2.80e-2)" "unprognostic (9.23e-2)" "unprognostic (3.49e-2)" "unprognostic (5.88e-4)" "unprognostic (2.13e-1)" "unprognostic (1.73e-2)" "unprognostic (8.01e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "unprognostic (9.29e-2)" "unprognostic (8.99e-2)" "unprognostic (1.53e-1)" "unprognostic (2.43e-1)" "unprognostic (6.45e-2)" 2.3 2.6 1.3 2.7 1.5 4.1 2.8 1.7 1.1 1.9 0.9 2.3 1.6 2.2 2.7 2.1 3.4 1.8 1.0 0.8 1.5 1.9 2.9 1.8 3.7 1.9 1.2 2.3 1.5 2.3 0.6 2.3 1.6 2.6 1.9 3.3 1.5 1.9 0.9 1.9 1.8 2.1 1.6 2.9 2.0 2.6 1.3 3.6 2.8 1.3 2.9 1.3 0.9 2.2 5.3 5.8 4.0 7.0 4.6 4.3 14.0 5.1 4.7 5.4 9.8 8.8 12.6 10.3 7.3 2.6 8.2 7.8 7.9 6.8 7.9 13.0 7.2 9.2 6.7 3.9 1.8 11.4 8.1 4.0 3.6 11.3 9.3 2.6 3.7 8.1 13.9 13.6 5.5 6.8 8.4 6.3 15.1 3.2 7.7 6.5 14.8 8.3 3.2 7.8 3.8 3.0 9.4 3.8 5.6 11.7 8.6 3.2 7.5 7.4 10.7 11.3 6.5 7.4 14.7 17.3 5.0 4.8 6.2 0.0 1.0 1.7 0.6 0.4 0.9 0.8 0.9 0.4 0.6 0.8 1.1 1.3 0.1 0.8 0.5 0.7 1.2 0.5 1.3 1.5 1.7 1.1 0.8 1.5 1.9 1.2 1.6 1.6 1.3 2.2 3.0 6.4 0.5 1.3 5.1 1.5 3.0 4.3 2.8 4.6 2.0 1.7 0.8 2.8 5.1 5.5 4.2 6.8 3.5 1.4 1.9 2.4 1.0 3.1 2.8 2.3 1.2 7.0 1.5 3.8 5.5 2.7 3.1 2.2 1.3 3.6 0.7 2.9 3.3 1.7 1.8 1.7 2.0 2.8 1.9 0.3 1.5 2.2 0.0 1.9 3.3 3.4 1.0 2.5 1.8 3.3 0.6 1.2 4.0 0.8 1.2 1.3 3.9 4.2 0.0 2.5 2.0 12.4 5.8 4.3 2.7 3.1 3.2 2.6 1.9 1.8 ANP32B "APRIL, PHAPI2, SSP29" ENSG00000136938 "Acidic nuclear phosphoprotein 32 family member B" Q92688 9 97983341-98015943 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063133, HPA067561, HPA069657" Supported Enhanced Nucleoplasm,Centrosome,Cytosol NA NA 570000 "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "HPA063133: AB_2684947, HPA067561: AB_2685861, HPA069657: " "unprognostic (2.82e-1)" "unprognostic (2.05e-2)" "unprognostic (4.57e-2)" "unprognostic (6.74e-2)" "unprognostic (1.85e-1)" "unprognostic (5.52e-2)" "prognostic unfavorable (1.98e-7)" "unprognostic (6.76e-3)" "unprognostic (5.70e-2)" "unprognostic (7.16e-2)" "unprognostic (3.50e-1)" "unprognostic (6.39e-2)" "unprognostic (9.22e-3)" "unprognostic (5.20e-2)" "unprognostic (2.36e-1)" "unprognostic (3.67e-2)" "unprognostic (1.78e-2)" 144.0 77.1 134.8 124.0 155.9 365.7 138.6 134.0 187.6 161.6 112.0 145.5 95.1 116.2 104.7 140.9 127.2 60.4 92.3 113.7 150.0 100.2 103.5 122.4 222.6 171.4 149.8 168.5 156.4 68.7 68.1 110.5 158.5 98.6 118.7 46.2 110.6 71.4 109.6 148.0 127.3 78.0 155.6 123.8 131.9 59.6 142.6 271.5 96.9 50.6 248.4 132.5 146.6 173.4 659.7 347.4 378.6 318.4 208.1 365.2 344.4 332.6 292.4 349.2 291.9 438.3 313.1 798.2 194.2 224.6 266.3 423.9 516.1 375.2 397.1 523.0 290.9 692.4 289.1 478.4 266.9 1201.9 386.8 278.7 268.8 280.9 574.0 283.2 307.9 701.5 1359.2 548.8 272.6 875.7 913.5 1062.0 148.2 638.8 341.2 537.8 589.5 381.7 228.8 269.9 304.2 265.8 390.4 376.2 364.5 185.3 213.2 444.0 377.0 226.5 367.3 288.3 355.5 493.2 601.3 469.1 209.7 472.7 432.1 91.3 83.6 118.8 65.2 95.5 89.3 106.1 122.5 92.8 100.5 93.0 143.8 112.1 34.2 74.1 149.7 96.4 162.5 85.3 134.8 155.9 134.0 187.6 113.7 150.0 171.4 149.8 158.5 155.6 142.6 173.4 127.9 86.6 101.8 7.8 227.7 180.7 201.3 180.0 208.9 61.1 100.4 126.0 85.8 112.9 120.7 75.4 25.0 345.5 159.5 159.1 97.8 144.9 114.9 73.8 176.3 146.9 149.9 709.4 5.8 171.6 537.9 121.9 123.3 117.5 119.7 247.9 159.5 96.6 284.7 119.5 6.2 242.2 75.3 310.6 152.0 95.2 146.3 222.5 128.1 14.0 263.5 68.9 149.3 8.0 18.8 137.1 151.1 145.2 266.5 260.6 177.7 101.9 56.3 42.1 151.2 113.4 189.4 204.3 339.0 243.0 154.1 333.1 217.6 188.9 302.7 234.1 ANP32E "LANP-L, LANPL, MGC5350" ENSG00000143401 "Acidic nuclear phosphoprotein 32 family member E" Q9BTT0 1 150218417-150236156 "Predicted intracellular proteins" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 222.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB021114, HPA063133, HPA067561" Supported Enhanced Nucleoplasm,Centrosome,Cytosol NA NA 280000 "Cluster 44: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Centrosome" Cytosol "CAB021114: AB_10057407, HPA063133: AB_2684947, HPA067561: AB_2685861" "unprognostic (1.04e-1)" "unprognostic (2.40e-1)" "unprognostic (2.51e-1)" "unprognostic (8.95e-2)" "unprognostic (1.69e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (4.50e-5)" "unprognostic (1.64e-1)" "unprognostic (6.58e-2)" "unprognostic (3.91e-2)" "unprognostic (7.73e-3)" "unprognostic (2.47e-1)" "prognostic unfavorable (3.82e-8)" "unprognostic (1.76e-2)" "unprognostic (1.60e-1)" "unprognostic (1.77e-1)" "unprognostic (3.52e-1)" 20.0 30.4 36.1 38.9 37.8 75.7 18.1 54.9 45.0 20.5 30.4 19.9 22.5 26.3 34.4 18.7 21.2 20.2 35.1 32.8 39.9 30.8 29.0 23.0 71.0 43.5 41.5 23.3 8.9 33.1 16.4 21.6 40.5 16.2 18.2 98.6 12.9 24.5 49.8 21.6 25.7 21.0 39.7 33.1 17.3 10.3 40.7 88.2 30.5 26.0 62.2 21.8 16.2 35.6 224.0 141.7 289.7 144.0 22.3 32.7 109.8 117.7 66.6 111.8 106.0 105.6 154.0 405.1 101.8 68.3 66.3 76.6 164.9 73.6 158.4 466.1 101.3 280.7 175.6 153.2 21.1 572.0 136.6 26.8 11.9 104.1 95.4 54.8 84.6 193.3 274.8 231.2 103.6 232.3 231.5 148.3 292.5 72.9 64.8 245.4 161.2 214.1 80.2 88.8 94.5 161.2 245.4 39.6 70.7 127.5 105.3 287.7 87.4 56.7 158.4 59.1 239.1 297.6 325.6 388.7 64.5 403.6 105.5 56.6 20.8 35.9 35.0 15.6 53.2 54.5 46.4 38.5 17.4 39.5 32.6 40.7 14.7 31.5 20.3 12.2 56.2 36.5 36.1 37.8 54.9 45.0 32.8 39.9 43.5 41.5 40.5 39.7 40.7 35.6 48.7 12.8 84.0 16.3 88.9 97.3 37.6 36.8 40.5 117.5 33.8 37.7 99.9 24.3 32.8 73.5 33.3 58.4 98.2 12.1 86.1 36.4 1.4 52.5 64.0 52.3 14.4 222.5 7.9 26.5 133.1 57.6 20.9 41.9 63.3 28.4 39.7 59.0 52.3 63.9 9.9 19.9 28.5 48.0 108.9 1.9 30.4 54.3 67.6 6.5 57.0 134.3 60.8 3.0 6.6 27.0 14.2 33.4 116.3 21.6 20.4 58.6 59.6 135.1 26.3 56.8 75.1 12.4 22.7 55.2 98.5 40.6 108.9 27.9 37.8 25.8 ARHGAP11A KIAA0013 ENSG00000198826 "Rho GTPase activating protein 11A" Q6P4F7 15 32615144-32639941 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 38.7;Extravillous trophoblasts: 23.7;Granulosa cells: 21.1;Plasma cells: 18.6;Spermatocytes: 24.7;Spermatogonia: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040830, HPA066481" Enhanced Approved Nucleoli,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "HPA040830: AB_10805830, HPA066481: " "unprognostic (5.00e-2)" "unprognostic (5.57e-2)" "unprognostic (6.10e-2)" "unprognostic (1.97e-1)" "unprognostic (2.93e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.05e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (4.87e-2)" "unprognostic (7.71e-2)" "prognostic unfavorable (2.92e-5)" "unprognostic (3.43e-2)" "unprognostic (1.07e-12)" "unprognostic (7.37e-2)" "unprognostic (5.23e-1)" "unprognostic (1.54e-2)" "unprognostic (9.64e-2)" 1.7 0.9 2.0 7.9 2.5 24.2 1.7 2.1 2.1 1.5 1.2 7.5 6.1 1.5 1.0 5.3 0.8 1.7 0.7 1.7 1.9 0.6 1.3 1.7 13.5 2.6 3.0 0.6 2.6 1.2 0.7 4.3 2.6 0.6 8.8 0.5 1.2 0.5 0.9 4.4 7.6 4.8 2.5 2.8 3.6 8.6 2.2 26.1 1.3 0.4 14.3 2.8 1.9 3.0 80.8 69.4 73.1 46.2 5.0 13.0 39.6 78.5 50.2 80.0 63.3 52.2 41.5 43.5 23.7 49.9 91.3 56.9 55.3 43.8 110.9 83.5 27.4 132.6 68.9 33.5 2.0 103.8 55.5 4.3 5.5 61.6 50.9 15.2 61.5 94.4 101.0 112.7 95.3 31.7 58.6 39.7 44.6 71.6 44.5 67.8 141.7 38.2 28.4 41.6 64.7 44.5 72.9 46.2 17.6 37.6 63.6 115.8 35.3 102.5 74.1 42.0 87.2 38.3 63.7 123.7 44.4 129.1 91.8 0.1 0.3 0.8 0.5 0.5 0.2 0.3 1.0 0.9 0.4 0.2 0.4 0.5 0.0 0.1 0.1 0.2 0.8 0.3 2.0 2.5 2.1 2.1 1.7 1.9 2.6 3.0 2.6 2.5 2.2 3.0 0.7 0.0 2.3 0.3 4.6 4.8 1.1 2.4 2.2 0.2 1.3 1.7 0.9 4.3 1.9 1.8 0.0 9.8 2.9 6.2 0.0 0.8 4.7 3.8 2.6 2.0 0.0 38.7 1.0 0.8 23.7 3.5 8.6 2.8 0.0 21.1 1.8 2.1 9.5 0.0 0.6 7.8 0.0 6.5 4.2 5.0 0.6 3.5 0.0 1.0 3.9 0.1 2.1 0.5 1.4 0.5 2.9 0.4 18.6 1.4 1.1 0.4 1.4 1.0 6.6 1.4 3.3 24.7 22.6 10.5 2.3 3.1 5.4 2.0 14.1 2.1 ARHGAP11B "B'-T, FAM7B1" ENSG00000285077 "Rho GTPase activating protein 11B" Q3KRB8 15 30624494-30649529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.6;lymphoid tissue: 1.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.6;Erythroid cells: 37.4;Late spermatids: 21.7;Muller glia cells: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 8.9;Karpas-707: 7.1" HPA064479 Uncertain Uncertain Vesicles NA NA "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA064479: AB_2685272" 0.2 0.0 0.0 0.8 0.2 2.6 0.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 1.4 0.2 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.1 0.2 0.2 0.3 0.1 1.4 0.1 0.0 0.8 0.1 0.1 1.2 1.0 2.8 1.3 0.0 0.4 0.8 3.2 0.9 1.6 1.8 0.6 1.8 1.5 0.1 0.2 0.9 1.4 1.6 0.6 1.3 3.0 3.9 3.1 8.9 0.2 0.0 2.8 1.8 0.1 0.0 0.4 0.2 0.5 0.9 1.9 0.8 7.1 1.7 1.0 1.0 2.8 0.8 0.7 1.2 1.9 3.2 0.8 0.7 1.3 1.5 0.8 1.9 0.7 0.4 0.7 1.5 1.4 1.0 2.6 1.7 0.5 0.8 1.4 0.5 3.1 0.4 3.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.3 0.0 1.5 1.0 6.1 2.0 1.0 2.8 1.8 3.2 0.6 0.3 0.7 0.0 0.6 1.8 6.2 0.0 5.1 7.0 0.0 0.4 22.6 0.4 1.3 1.1 0.0 37.4 0.4 0.6 0.0 2.3 15.3 0.7 1.3 6.9 4.2 0.8 0.0 3.3 0.2 8.3 2.0 7.9 3.1 21.7 2.1 3.3 0.0 1.0 4.8 17.3 4.1 0.0 0.7 0.4 2.5 1.2 12.6 1.0 1.6 0.6 1.2 2.3 0.0 1.3 1.5 15.5 12.9 6.9 1.4 0.0 5.8 1.2 12.1 0.9 ARHGAP19 "FLJ00194, MGC14258" ENSG00000213390 "Rho GTPase activating protein 19" Q14CB8 10 97222173-97292673 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Spermatocytes: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA035777, HPA043231" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane" "HPA035777: AB_2674777, HPA043231: AB_10796791" "unprognostic (5.88e-2)" "unprognostic (2.39e-2)" "unprognostic (2.47e-2)" "unprognostic (1.91e-2)" "unprognostic (1.68e-1)" "unprognostic (8.79e-3)" "unprognostic (1.60e-3)" "unprognostic (2.00e-2)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (6.76e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (7.47e-5)" "unprognostic (1.12e-2)" "unprognostic (1.56e-1)" "unprognostic (2.23e-2)" "unprognostic (4.29e-2)" 3.2 2.1 2.4 7.1 3.9 18.8 7.6 2.9 2.0 3.7 0.6 4.3 3.6 5.5 2.6 4.0 4.7 3.4 3.3 1.6 3.2 3.9 2.4 4.7 13.3 4.3 3.2 9.3 1.6 5.5 0.5 5.3 4.4 3.6 4.5 3.2 3.2 3.0 1.8 3.6 5.3 4.5 3.3 7.9 3.6 18.5 2.9 21.3 3.2 4.2 13.2 2.9 2.0 5.9 18.5 6.0 31.9 56.0 2.1 8.3 9.8 9.0 9.1 13.9 9.9 11.2 16.1 40.9 7.4 6.2 8.3 12.3 27.1 11.2 17.8 20.4 14.7 27.0 7.8 7.8 2.1 42.1 27.8 4.2 3.9 9.8 22.3 4.7 19.6 57.3 27.1 21.0 12.1 8.9 39.3 9.1 16.9 12.2 5.5 45.5 27.1 11.4 4.2 7.8 2.5 14.5 6.7 3.1 14.5 11.9 19.4 22.2 9.1 5.7 6.8 8.9 23.6 18.6 20.7 54.3 7.0 48.7 6.4 21.5 7.2 11.1 5.0 6.8 4.7 5.5 4.9 4.7 5.4 5.3 5.6 5.0 15.8 4.4 6.1 3.0 6.3 5.5 2.4 3.9 2.9 2.0 1.6 3.2 4.3 3.2 4.4 3.3 2.9 5.9 5.8 3.2 3.2 0.0 4.1 0.9 1.4 2.8 3.4 2.8 3.6 8.8 1.9 2.8 1.6 0.0 0.0 2.0 3.6 2.2 0.0 1.3 9.1 2.4 2.6 5.4 0.0 6.7 0.0 1.6 3.5 3.9 1.5 3.6 5.1 5.6 11.7 2.6 3.5 6.7 0.0 1.9 2.0 9.3 1.9 6.3 3.4 6.1 1.8 0.0 5.4 1.7 5.2 0.0 0.0 1.4 2.9 4.1 5.8 2.6 2.6 0.7 4.8 1.3 0.0 3.1 2.2 13.7 10.4 5.3 2.4 1.0 3.5 3.4 3.5 1.6 ARL6IP1 "AIP1, ARL6IP, ARMER, KIAA0069, SPG61" ENSG00000170540 "ADP ribosylation factor like GTPase 6 interacting protein 1" Q15041 16 18791669-18801572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045307 Uncertain Approved "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (2.42e-1)" "unprognostic (3.47e-2)" "unprognostic (4.07e-3)" "unprognostic (1.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (2.58e-2)" "unprognostic (1.76e-2)" "unprognostic (3.88e-2)" "unprognostic (6.83e-2)" "unprognostic (1.91e-3)" "unprognostic (3.33e-2)" "unprognostic (1.13e-2)" "unprognostic (7.09e-2)" "unprognostic (4.60e-2)" "unprognostic (6.32e-3)" "unprognostic (5.36e-3)" 142.0 171.3 206.4 77.7 217.3 209.7 112.9 200.6 282.2 79.2 182.4 140.9 138.8 70.8 122.9 70.0 86.6 131.9 32.1 227.7 209.2 150.1 359.6 79.6 132.6 192.0 197.8 101.6 81.7 180.6 40.7 90.3 200.0 75.9 123.4 316.0 84.3 70.4 23.1 66.1 123.4 69.1 185.0 72.8 125.8 129.9 200.5 158.5 112.5 51.5 113.4 132.5 47.4 197.6 375.3 334.6 417.8 331.6 146.7 93.5 373.2 208.9 196.9 311.0 246.7 205.7 851.1 315.7 388.4 198.0 209.2 388.9 303.7 144.2 359.1 421.2 137.1 227.9 192.5 549.1 116.4 329.9 232.0 78.6 137.7 216.2 224.0 229.1 316.1 180.5 251.0 318.5 607.6 331.4 229.9 238.3 520.0 311.7 109.8 387.9 535.9 266.0 337.8 206.1 255.2 287.5 466.5 279.8 204.5 280.1 576.1 315.9 189.2 204.2 192.9 147.1 384.1 109.5 209.5 383.2 182.8 215.6 405.5 211.4 125.2 84.2 179.4 119.5 167.0 163.2 159.0 199.1 127.4 160.7 137.9 166.4 105.9 179.2 133.3 221.6 281.5 295.0 206.4 217.3 200.6 282.2 227.7 209.2 192.0 197.8 200.0 185.0 200.5 197.6 306.4 67.3 51.0 56.8 170.6 372.6 241.4 170.1 309.6 189.2 256.5 216.8 30.6 361.8 128.7 286.9 131.3 296.7 164.6 269.0 174.1 398.2 74.6 93.3 61.7 188.1 145.9 503.8 70.4 203.1 385.4 150.4 257.9 158.3 135.8 198.0 275.5 457.4 253.9 89.2 94.2 234.6 229.9 275.8 424.6 42.7 84.8 205.8 200.9 39.4 267.3 318.5 142.2 57.3 50.3 271.0 288.5 110.9 107.5 219.4 217.0 189.1 126.6 218.0 92.1 125.6 118.6 193.6 56.6 295.2 326.5 326.6 186.9 53.1 319.7 323.8 ASF1B FLJ10604 ENSG00000105011 "Anti-silencing function 1B histone chaperone" Q9NVP2 19 14119512-14136613 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 32.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Early spermatids: 36.4;Erythroid cells: 43.6;Extravillous trophoblasts: 35.4;Spermatocytes: 73.2;Spermatogonia: 87.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "neutrophil: 60.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 60.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA054036, HPA069385" Enhanced Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054036: AB_2682350, HPA069385: " "unprognostic (3.14e-1)" "prognostic favorable (4.45e-5)" "unprognostic (2.41e-3)" "unprognostic (2.40e-1)" "unprognostic (2.15e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.87e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.48e-3)" "prognostic unfavorable (2.22e-16)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (3.92e-2)" "unprognostic (4.31e-2)" 0.9 1.4 0.2 5.6 0.3 11.7 1.3 0.3 0.2 2.2 0.1 7.4 5.3 1.0 0.1 10.3 0.7 0.7 0.7 0.1 0.2 1.0 1.3 2.1 12.5 0.3 0.2 0.7 0.7 0.3 0.7 3.6 0.3 0.8 7.7 0.0 1.9 0.3 0.5 3.2 6.0 2.0 0.2 6.7 3.2 32.0 0.3 23.2 0.6 0.4 14.7 1.8 3.2 0.3 64.6 25.3 37.7 28.9 3.8 3.6 16.2 33.1 28.3 63.8 79.5 26.5 31.6 59.1 30.0 17.5 26.5 38.0 41.8 24.1 49.7 54.0 26.9 55.5 48.7 18.6 0.2 39.0 35.1 0.7 1.7 35.8 12.4 7.2 25.1 44.1 50.2 83.8 31.8 75.7 80.8 34.3 17.3 69.1 56.7 77.0 56.0 51.6 20.1 28.3 46.0 16.5 39.8 29.2 17.4 10.3 22.1 41.5 10.6 36.0 21.6 91.0 56.6 43.2 46.5 80.3 28.0 71.9 36.1 0.7 6.2 1.5 1.7 8.0 0.9 1.1 1.5 2.0 1.2 0.9 0.9 1.7 60.1 1.7 8.5 0.5 5.1 3.2 0.2 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.3 0.2 0.3 0.3 1.0 0.0 0.6 0.3 5.6 2.5 2.4 4.5 1.2 0.1 4.8 8.5 1.2 1.5 1.1 0.0 0.0 36.1 3.8 11.7 0.0 1.0 36.4 2.1 1.3 2.1 1.2 43.6 0.5 1.2 35.4 4.1 23.4 2.3 4.5 9.2 0.4 0.3 21.5 0.0 0.4 9.9 8.2 5.6 5.6 29.1 0.0 5.0 1.8 1.0 2.1 0.3 4.1 0.0 0.5 1.1 2.2 0.7 20.1 1.0 2.4 0.3 0.2 0.9 0.0 1.1 3.3 73.2 87.8 8.3 1.1 10.4 5.3 3.0 20.9 2.4 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Spermatocytes: 73.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" "Intracellular and membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (3.12e-1)" "unprognostic (7.36e-2)" "unprognostic (1.12e-2)" "unprognostic (1.36e-3)" "unprognostic (3.33e-1)" "unprognostic (1.05e-2)" "unprognostic (1.28e-4)" "unprognostic (1.77e-1)" "unprognostic (1.79e-3)" "unprognostic (7.24e-2)" "unprognostic (2.78e-1)" "unprognostic (3.19e-3)" "unprognostic (6.30e-10)" "unprognostic (3.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (1.38e-1)" 0.7 0.4 0.3 2.1 0.2 12.3 1.2 2.6 0.5 0.8 0.1 1.2 1.4 1.0 0.4 1.3 0.7 0.5 0.4 0.3 0.2 0.4 0.5 0.8 3.6 0.2 0.1 0.9 0.5 0.3 0.5 1.4 0.3 0.6 1.6 2.5 0.7 0.4 0.4 2.5 1.4 0.6 0.1 1.4 1.1 2.0 0.3 5.3 0.6 0.1 2.9 0.6 0.9 0.6 7.2 6.0 14.0 13.3 0.3 1.4 5.5 6.3 3.2 6.9 9.8 6.6 5.1 19.5 5.9 2.9 4.7 13.0 9.1 4.7 12.4 4.4 7.9 11.7 8.0 4.6 0.2 23.1 9.2 0.6 0.6 10.1 3.5 1.4 3.6 18.7 18.7 15.9 4.6 4.2 26.1 11.5 8.2 5.3 2.9 17.6 26.4 9.3 1.8 7.6 8.1 7.2 7.0 4.0 3.7 7.6 7.6 10.2 2.8 8.3 11.3 12.0 11.4 5.2 5.9 24.0 3.6 10.7 8.4 0.4 0.2 0.3 0.3 0.3 0.2 0.3 0.1 0.2 0.1 0.4 0.2 0.2 0.6 0.6 0.1 0.5 0.3 0.1 0.3 0.2 2.6 0.5 0.3 0.2 0.2 0.1 0.3 0.1 0.3 0.6 4.3 3.2 4.1 6.8 9.9 4.7 3.1 2.6 3.4 19.3 4.7 5.1 2.7 0.0 2.6 3.7 0.0 21.7 10.7 6.6 0.0 4.1 13.9 4.4 8.5 5.4 0.0 59.3 20.4 2.9 21.1 5.4 9.7 5.1 3.8 32.6 2.9 0.7 8.7 11.8 17.4 8.6 2.0 2.8 7.4 7.8 3.7 5.7 7.2 11.2 10.0 2.9 12.3 16.6 14.9 4.0 2.4 2.2 24.4 2.4 2.3 0.5 2.7 21.3 0.0 7.4 6.5 73.3 34.5 9.3 4.5 7.9 10.5 8.4 13.0 2.3 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.1;lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Erythroid cells: 59.3;Extravillous trophoblasts: 89.1;Granulosa cells: 24.7;Hofbauer cells: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.1 1.2 0.1 14.2 0.2 44.1 1.7 0.2 0.2 3.0 0.1 11.1 12.1 1.6 0.4 18.6 0.6 1.5 0.7 0.1 0.2 0.9 2.0 2.5 36.7 0.1 0.3 0.5 0.6 0.3 0.2 8.2 0.3 0.8 11.0 0.0 2.7 0.3 5.5 9.3 11.6 3.2 0.0 12.0 4.6 1.2 0.4 60.1 0.6 0.0 36.6 3.5 5.9 0.2 196.5 130.9 191.1 93.0 4.2 6.5 73.4 91.7 49.5 186.2 170.6 171.5 57.4 193.3 46.2 37.0 77.0 139.8 140.1 62.6 153.7 84.9 231.3 115.7 78.3 146.1 0.7 62.2 109.2 3.5 2.9 109.4 67.7 18.5 86.5 123.6 73.3 73.4 82.9 92.9 225.1 87.4 119.6 63.9 57.6 149.8 176.1 80.5 41.2 38.2 41.2 59.1 81.7 36.5 61.2 56.5 63.5 41.4 33.9 74.3 75.6 67.6 243.3 53.2 37.7 147.9 35.7 92.9 153.4 0.0 0.4 0.6 0.5 0.3 0.1 1.1 1.3 2.1 0.5 2.5 0.1 0.7 0.9 0.3 0.2 0.2 7.9 0.9 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.4 0.2 0.3 0.0 0.5 0.0 7.6 4.5 1.8 6.1 0.6 0.0 1.8 2.2 1.4 0.0 2.6 0.0 0.0 40.5 1.8 13.2 0.0 0.4 0.1 0.5 1.6 3.1 0.0 59.3 0.0 0.0 89.1 5.7 6.1 2.1 4.5 24.7 6.1 0.7 29.4 0.0 0.0 10.8 0.0 5.7 7.3 0.2 0.6 5.1 1.8 0.0 0.9 0.0 3.1 0.0 0.1 0.3 2.8 0.0 15.4 1.2 1.5 0.1 0.2 0.0 0.0 0.1 4.8 1.6 7.2 11.8 2.4 9.0 4.3 1.0 22.0 2.8 BANF1 BAF ENSG00000175334 "BAF nuclear assembly factor 1" O75531 11 66002228-66004149 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB032896, HPA039242" Enhanced Supported Nucleoplasm,Cytosol NA NA 690000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB032896: AB_2061090, HPA039242: AB_2676409" "unprognostic (1.69e-1)" "unprognostic (4.46e-3)" "unprognostic (2.04e-1)" "unprognostic (9.59e-3)" "unprognostic (1.23e-1)" "unprognostic (3.70e-3)" "unprognostic (6.16e-3)" "unprognostic (8.39e-3)" "unprognostic (2.31e-1)" "unprognostic (5.07e-2)" "unprognostic (1.76e-2)" "unprognostic (4.57e-1)" "unprognostic (7.36e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-1)" "unprognostic (1.83e-3)" "unprognostic (6.39e-2)" 116.4 149.0 252.8 144.8 256.8 127.2 151.4 261.0 312.9 135.4 248.4 153.7 107.2 168.0 248.5 136.0 279.6 100.9 272.2 249.9 259.6 115.6 174.0 111.3 178.5 258.4 254.4 207.6 132.5 148.8 69.0 120.8 261.1 139.2 155.9 98.7 148.2 169.7 582.1 121.0 105.0 190.0 258.5 116.0 92.7 111.1 254.8 220.7 164.6 394.8 211.9 140.6 82.4 274.5 665.5 712.0 452.8 427.9 237.7 306.5 220.5 364.7 349.4 715.9 447.0 415.3 496.1 606.5 651.8 503.3 544.0 433.5 641.7 600.1 559.1 476.4 411.5 699.5 431.3 537.0 296.0 503.4 480.4 292.5 404.6 453.8 418.1 404.6 494.6 526.5 552.5 459.6 687.5 1196.3 607.7 1023.8 494.7 410.4 525.6 507.0 447.1 1297.4 647.9 361.7 362.9 458.0 399.1 636.4 469.4 352.9 698.8 378.6 350.4 535.8 574.2 601.8 515.8 313.6 680.4 771.1 442.7 420.2 485.5 112.7 231.7 82.2 165.2 239.1 159.1 243.7 139.0 160.5 252.9 234.6 166.0 174.4 28.7 219.7 266.2 238.2 125.5 324.0 252.8 256.8 261.0 312.9 249.9 259.6 258.4 254.4 261.1 258.5 254.8 274.5 135.8 54.5 41.9 11.4 112.7 126.8 154.6 301.2 142.9 52.8 164.8 230.0 32.1 102.9 153.6 196.8 25.0 296.5 101.4 70.7 326.8 196.8 17.1 164.8 147.2 126.5 142.8 144.5 12.3 177.3 346.6 126.6 86.6 116.2 140.2 199.7 79.9 130.8 324.5 50.5 13.4 171.4 223.8 80.6 169.8 41.9 142.0 124.7 186.7 8.4 155.9 123.8 186.4 9.0 22.2 170.3 107.1 123.8 110.8 126.8 77.4 251.5 187.7 57.8 72.3 123.9 145.5 250.2 325.1 227.0 118.1 174.7 104.9 172.6 196.2 148.9 BCL2L12 ENSG00000126453 "BCL2 like 12" Q9HB09 19 49665142-49673916 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020856 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane" "HPA020856: AB_1845320" "unprognostic (2.59e-1)" "unprognostic (3.96e-2)" "unprognostic (2.24e-1)" "unprognostic (5.72e-2)" "unprognostic (3.64e-1)" "unprognostic (3.68e-2)" "unprognostic (6.80e-3)" "unprognostic (3.87e-3)" "unprognostic (6.12e-2)" "unprognostic (8.90e-2)" "unprognostic (1.60e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (8.75e-5)" "unprognostic (8.67e-2)" "unprognostic (3.62e-2)" "unprognostic (2.37e-1)" "unprognostic (2.56e-1)" 8.5 8.5 3.8 14.7 3.9 18.2 9.5 3.9 5.1 8.3 5.0 11.9 10.5 9.9 3.2 13.4 9.5 6.5 9.4 3.6 3.8 7.8 16.6 9.6 20.6 4.4 4.2 9.7 15.5 4.5 2.7 10.3 4.1 11.3 7.3 1.7 11.7 5.0 14.0 8.5 11.9 6.8 4.1 16.7 11.7 10.1 4.1 17.3 7.6 13.5 15.8 9.6 8.7 4.3 105.2 63.7 49.8 94.8 12.6 12.6 56.9 58.2 23.3 57.2 60.6 89.2 55.4 58.4 26.7 20.2 32.4 49.7 46.3 39.4 30.7 74.1 97.4 53.1 43.5 62.0 11.4 56.6 62.2 15.5 19.0 64.3 18.2 11.5 38.7 79.2 138.8 73.3 30.8 59.1 67.6 91.8 62.4 61.8 77.4 86.6 54.3 62.7 24.8 52.0 0.9 29.4 59.5 79.0 41.8 35.6 33.0 70.3 22.8 64.1 75.2 45.5 96.4 61.2 102.4 114.3 27.2 78.0 64.3 11.0 7.4 17.0 12.5 12.2 14.6 14.8 13.2 12.3 6.5 14.6 12.8 13.1 10.9 15.8 8.6 25.9 14.4 6.3 3.8 3.9 3.9 5.1 3.6 3.8 4.4 4.2 4.1 4.1 4.1 4.3 10.2 9.6 13.1 3.3 22.1 32.2 37.4 23.3 14.2 1.0 35.2 34.2 5.0 10.0 16.5 5.5 0.0 70.3 18.2 14.6 7.9 25.7 8.3 17.0 11.5 13.2 6.7 18.5 0.2 25.8 126.3 16.2 9.2 20.1 9.5 18.9 11.0 13.1 37.6 0.0 0.2 15.7 18.3 12.6 16.1 6.4 6.5 15.5 26.6 1.0 22.1 3.5 24.7 0.0 1.6 34.5 16.6 6.0 44.3 20.5 6.5 10.4 12.6 1.2 13.1 14.0 15.1 11.6 22.3 19.7 19.5 55.7 15.7 11.7 23.3 27.7 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 0.3 0.2 0.9 3.6 1.1 5.7 0.5 2.3 0.9 0.1 0.3 1.4 1.0 0.4 0.4 0.6 0.3 0.3 0.3 0.8 1.1 0.1 0.1 0.4 6.4 1.2 1.4 0.1 0.2 0.0 0.6 1.2 1.1 0.1 1.7 2.4 7.8 0.0 0.5 0.4 1.6 0.4 1.0 1.6 1.1 2.2 0.9 7.9 0.3 0.1 6.2 1.0 0.2 1.0 13.0 14.4 20.4 12.6 0.1 0.9 14.6 9.4 3.2 11.1 13.4 11.7 10.1 35.1 5.9 2.6 14.1 20.4 25.7 7.1 15.1 19.1 20.5 36.4 14.8 3.9 0.0 33.7 17.3 0.3 0.1 10.6 4.7 1.3 7.9 16.9 32.7 9.9 11.0 7.4 28.3 14.5 22.2 24.9 4.2 25.4 39.1 14.7 2.3 18.9 14.6 14.7 8.5 11.5 4.8 18.1 7.2 23.4 3.7 8.6 13.6 9.6 21.0 6.4 30.4 39.5 5.6 25.8 15.7 1.7 0.6 2.6 1.6 0.8 2.6 4.6 1.4 2.1 0.7 2.3 1.0 1.1 0.7 3.1 1.0 0.7 3.2 0.9 0.9 1.1 2.3 0.9 0.8 1.1 1.2 1.4 1.1 1.0 0.9 1.0 0.9 3.2 8.9 1.0 12.9 0.3 0.5 0.5 0.6 3.6 1.3 1.0 7.9 0.0 4.2 0.0 2.1 5.5 6.9 2.2 1.9 1.0 2.7 1.3 1.3 2.0 0.0 18.3 0.7 0.7 6.8 1.8 3.6 1.7 13.3 8.1 2.2 0.6 5.7 0.0 8.6 1.3 0.0 7.7 1.3 1.6 0.0 7.7 0.0 7.5 2.7 1.7 10.3 58.3 2.6 1.2 0.3 0.4 20.6 0.7 0.2 0.0 5.4 7.1 0.0 0.9 1.7 17.1 12.9 2.2 0.6 1.0 10.2 0.7 4.0 0.4 BORA "C13orf34, FLJ22624" ENSG00000136122 "BORA aurora kinase A activator" Q6PGQ7 13 72727749-72756198 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 13.5;Sertoli cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040866 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA040866: AB_10794868" "unprognostic (9.93e-2)" "unprognostic (7.18e-2)" "unprognostic (4.57e-2)" "unprognostic (7.09e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-2)" "unprognostic (1.37e-4)" "unprognostic (2.65e-2)" "unprognostic (2.82e-3)" "unprognostic (6.18e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-2)" "unprognostic (5.32e-12)" "unprognostic (7.04e-3)" "unprognostic (2.88e-1)" "unprognostic (9.93e-2)" "unprognostic (2.28e-2)" 1.6 1.3 1.2 4.3 1.2 6.0 2.4 1.4 1.7 1.6 1.9 4.2 4.3 1.3 1.5 3.5 1.4 1.3 1.0 1.2 1.3 1.8 1.7 1.8 7.6 1.6 1.3 1.2 1.7 0.5 1.9 2.3 1.5 1.8 5.0 3.5 1.9 1.0 1.1 4.2 3.5 1.7 1.1 4.2 3.2 4.0 1.4 8.1 1.9 0.9 6.8 2.2 2.2 1.5 32.5 8.5 19.6 14.7 2.4 2.4 11.6 9.8 8.6 17.9 18.1 20.6 17.2 23.8 6.4 6.4 10.3 15.0 17.1 11.5 22.1 20.9 12.3 28.7 11.4 15.8 1.7 54.2 17.1 1.9 2.6 8.9 15.1 5.0 14.6 22.8 12.7 10.7 14.6 9.8 20.8 21.8 10.8 36.8 6.0 16.4 12.3 10.6 6.5 10.0 6.9 7.0 12.0 12.8 10.2 15.0 6.4 24.6 4.8 5.8 9.7 8.3 16.3 6.9 7.0 14.8 16.3 24.8 13.9 1.3 1.1 0.5 1.9 1.9 2.3 1.6 1.8 2.0 1.9 1.9 1.6 2.5 0.1 1.8 1.2 1.4 1.9 1.1 1.2 1.2 1.4 1.7 1.2 1.3 1.6 1.3 1.5 1.1 1.4 1.5 1.6 3.2 2.8 3.6 5.4 0.6 1.3 2.2 3.4 1.7 1.4 1.3 0.3 1.5 2.1 1.8 2.1 7.5 3.9 3.1 0.0 1.9 12.6 2.2 2.3 1.4 0.0 13.5 4.3 2.6 11.5 1.7 3.6 2.4 1.3 5.1 1.8 0.4 4.6 8.4 3.1 2.7 0.0 2.8 1.5 2.7 0.9 2.8 0.0 3.7 3.5 1.1 4.1 2.5 7.3 1.7 2.2 1.2 5.2 1.2 3.2 0.8 2.7 2.3 13.1 1.6 1.5 11.8 4.3 3.4 1.1 2.9 4.1 1.5 5.8 1.4 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.9;lymphoid tissue: 27.5;testis: 30.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.8;Granulosa cells: 66.1;Plasma cells: 35.2;Spermatocytes: 85.6;Spermatogonia: 20.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 221.5" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 0.5 0.4 0.1 8.4 0.3 11.9 1.2 0.1 0.1 0.9 0.0 4.3 4.0 1.0 3.5 4.7 0.5 0.9 0.6 0.1 0.1 0.3 0.6 1.2 15.9 0.1 0.6 0.4 0.2 0.7 0.0 3.2 0.3 0.3 5.7 0.1 0.9 0.1 0.1 2.7 3.5 2.2 0.0 5.6 1.9 30.3 0.4 27.5 0.4 0.2 17.0 2.4 1.6 0.3 96.0 29.4 68.5 46.8 3.8 5.3 38.8 50.9 32.9 85.6 62.3 58.3 55.0 64.7 30.9 30.1 80.1 43.2 93.9 35.0 105.7 51.4 45.6 221.5 26.2 50.6 0.8 63.5 57.0 1.7 2.8 65.2 33.1 12.7 49.8 73.2 96.8 126.5 76.8 33.7 126.3 39.0 71.2 39.4 55.3 69.3 64.2 102.7 18.3 27.0 48.3 21.4 34.2 31.4 27.2 44.1 24.0 60.6 19.1 39.7 57.5 28.8 69.0 67.3 65.5 75.4 24.2 48.6 69.8 1.1 0.0 0.2 0.2 0.0 0.3 0.5 0.9 0.5 0.1 0.5 0.6 0.4 0.0 0.5 0.0 0.9 1.5 0.3 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.3 0.0 0.4 0.3 0.2 0.0 1.5 0.0 5.5 0.5 0.5 2.0 0.6 0.0 0.9 0.8 1.1 0.0 1.6 0.0 0.0 5.8 2.5 2.4 0.0 0.3 13.5 4.5 1.5 1.1 0.0 24.8 0.2 0.0 9.8 2.2 2.0 2.2 0.0 66.1 1.8 0.3 8.1 0.0 0.2 3.1 4.1 1.6 1.4 7.5 0.3 2.0 0.0 0.0 0.6 0.0 0.0 0.5 1.0 0.1 0.0 0.4 35.2 0.5 0.3 0.1 1.8 0.0 6.6 0.2 3.7 85.6 20.0 4.0 0.4 0.7 2.9 0.5 5.9 0.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008419 Supported Cytosol Yes Yes "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 0.4 0.5 0.1 6.7 0.1 17.8 1.6 0.3 0.2 1.0 7.7 4.6 4.7 1.2 0.3 5.2 0.6 0.6 0.3 0.3 0.1 0.3 0.4 1.0 12.6 0.0 0.1 0.2 0.2 0.2 0.1 3.4 0.1 0.4 6.0 0.1 0.9 0.2 0.0 3.5 4.1 2.1 0.0 3.1 2.4 22.2 0.2 35.7 0.5 0.0 15.0 1.5 1.7 0.0 66.5 32.8 103.0 41.5 2.5 7.1 33.2 60.9 34.2 64.6 55.7 48.1 25.0 59.7 33.5 22.7 59.0 72.6 98.8 33.2 70.5 51.8 52.1 86.4 83.6 45.5 0.2 79.0 45.7 1.6 2.0 39.2 37.1 12.9 47.7 66.5 76.4 61.7 65.6 22.5 62.5 48.9 70.2 55.6 36.8 66.5 83.7 45.2 19.9 33.1 67.1 40.8 38.0 35.9 13.3 45.1 41.9 40.9 27.6 49.3 51.8 49.2 55.5 32.1 58.2 95.6 26.3 87.8 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 3.2 1.1 0.3 1.8 0.8 0.3 1.0 1.8 0.7 0.9 2.0 0.8 0.0 1.9 0.0 0.0 5.4 0.6 1.8 0.0 0.4 3.0 0.9 1.4 1.0 0.0 23.5 0.7 0.0 6.7 2.4 5.6 2.1 0.0 12.9 1.1 0.3 5.2 0.0 0.7 2.5 0.0 1.9 1.7 3.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.5 0.4 12.6 0.3 0.3 0.1 0.2 0.2 6.6 0.2 1.7 79.2 26.8 6.9 0.3 0.8 1.8 0.8 5.4 0.6 BUB3 BUB3L ENSG00000154473 "BUB3 mitotic checkpoint protein" O43684 10 123154402-123170467 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003601, CAB037075" Supported Supported Nucleoplasm NA Yes 39000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB037075: AB_1078310, HPA003601: AB_1078309" "unprognostic (7.82e-2)" "prognostic favorable (2.04e-4)" "unprognostic (9.07e-2)" "unprognostic (1.83e-1)" "unprognostic (7.93e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (4.45e-5)" "unprognostic (6.04e-3)" "unprognostic (9.41e-2)" "unprognostic (6.30e-3)" "unprognostic (2.69e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (3.81e-7)" "unprognostic (8.80e-2)" "unprognostic (7.64e-2)" "unprognostic (1.51e-1)" "unprognostic (7.71e-2)" 36.6 49.8 27.3 63.3 34.5 102.9 41.1 35.0 35.0 36.0 30.7 49.0 42.2 35.7 35.2 56.6 37.6 35.8 28.0 31.9 36.4 32.6 34.9 33.5 99.9 34.1 50.6 42.9 30.1 32.6 36.0 38.2 39.6 30.6 49.1 25.5 39.5 28.8 36.9 44.1 47.7 36.4 35.7 52.9 38.4 58.5 33.0 100.6 37.4 33.5 87.2 49.5 40.4 48.6 309.8 302.5 190.4 211.5 105.4 100.3 166.2 316.2 329.5 340.3 268.8 266.3 203.2 275.9 116.3 145.2 163.6 195.9 285.1 343.0 349.9 228.8 294.2 173.0 355.1 291.8 110.1 338.1 206.8 86.5 132.9 307.9 382.4 182.1 232.7 228.9 216.1 266.7 308.4 264.1 281.8 206.9 117.6 159.0 293.0 378.6 96.2 175.7 156.3 333.1 141.4 143.1 179.2 116.6 151.9 77.5 135.0 173.4 188.5 262.4 163.9 167.6 473.8 143.0 220.6 433.9 143.0 333.2 113.2 200.3 113.2 165.7 246.0 122.2 224.1 216.7 223.0 251.0 119.1 209.7 237.9 249.3 56.1 241.6 112.3 127.6 366.9 294.0 27.3 34.5 35.0 35.0 31.9 36.4 34.1 50.6 39.6 35.7 33.0 48.6 55.8 25.6 36.5 15.3 99.7 130.5 65.5 154.6 73.4 30.8 53.4 48.8 39.2 44.3 66.9 38.6 10.4 108.1 119.0 37.1 70.5 68.8 160.8 26.1 41.4 62.1 40.7 93.6 14.4 58.9 136.5 62.6 34.7 28.1 50.7 56.3 45.0 43.0 80.7 10.1 12.9 57.3 118.0 58.1 68.6 159.3 45.1 53.1 96.0 16.9 140.4 55.7 97.9 21.6 35.9 64.1 40.2 46.3 107.1 64.7 44.5 78.4 51.2 25.1 105.2 42.2 70.6 199.8 145.4 86.3 133.3 65.0 150.3 84.1 67.8 62.9 C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 13.5" "Cell type enhanced" "Detected in many" "Microglial cells: 30.0;Spermatocytes: 37.1;Spermatogonia: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA023778: AB_1848665, HPA024451: AB_1848667" "unprognostic (4.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (9.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.40e-2)" "unprognostic (2.50e-3)" "unprognostic (2.09e-1)" "unprognostic (9.11e-3)" "unprognostic (8.79e-2)" "unprognostic (3.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.65e-8)" "unprognostic (1.76e-1)" "unprognostic (2.81e-2)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" 1.8 1.2 0.6 3.3 0.9 9.0 2.9 1.7 0.8 2.3 0.5 2.6 1.2 2.9 1.0 2.0 1.5 1.4 1.0 0.5 0.4 1.1 2.6 1.7 6.3 1.0 0.6 2.2 1.5 13.5 1.0 3.4 0.8 1.8 4.1 5.4 1.5 2.0 0.9 2.4 1.8 2.7 0.7 2.8 1.9 10.3 0.9 11.6 1.7 1.5 7.9 3.1 1.7 1.5 32.7 17.5 21.9 11.3 3.5 4.8 32.2 21.1 10.7 30.0 30.6 19.1 27.7 29.0 9.3 7.0 10.7 26.0 27.6 14.7 34.3 16.9 16.5 27.1 23.0 14.1 1.2 35.8 11.3 1.5 1.9 22.5 5.3 3.5 12.8 16.8 44.9 48.0 24.8 7.9 31.5 10.3 28.8 22.9 12.1 23.3 24.7 19.5 4.0 16.1 16.2 16.9 13.4 22.1 6.9 20.6 21.0 18.3 9.5 24.1 19.1 17.8 28.9 12.9 20.9 30.6 9.0 26.4 24.1 2.2 0.8 1.0 0.6 1.9 0.4 1.4 0.6 0.6 1.2 1.4 0.3 0.5 0.1 2.1 2.3 0.4 0.7 0.6 0.6 0.9 1.7 0.8 0.5 0.4 1.0 0.6 0.8 0.7 0.9 1.5 1.2 0.0 3.3 4.2 4.0 1.8 2.7 2.6 1.2 4.1 1.7 1.8 0.5 0.0 1.5 0.0 6.2 9.1 1.6 1.9 0.0 2.7 8.7 0.9 2.1 2.2 0.0 3.4 9.9 3.4 9.1 2.5 2.6 1.2 4.5 9.8 2.9 3.8 6.2 1.7 9.6 1.2 6.1 3.5 2.1 4.1 2.1 3.0 3.6 30.0 1.3 2.4 0.0 13.0 13.2 3.0 0.3 3.8 5.5 1.0 0.8 0.7 2.0 6.6 6.6 1.4 2.6 37.1 20.3 2.8 1.0 3.8 3.3 2.2 2.6 2.4 CBX3 HP1Hs-gamma ENSG00000122565 "Chromobox 3" Q13185 7 26201162-26213607 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001973, HPA004902" Supported Supported "Nucleoplasm,Nuclear bodies" NA Yes 180000 "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "CAB001973: , HPA004902: AB_1850635" "prognostic unfavorable (7.92e-4)" "unprognostic (1.43e-1)" "unprognostic (4.84e-2)" "unprognostic (1.12e-2)" "unprognostic (4.85e-2)" "unprognostic (9.25e-3)" "prognostic unfavorable (2.20e-8)" "unprognostic (2.13e-2)" "unprognostic (3.95e-2)" "unprognostic (3.71e-3)" "prognostic unfavorable (4.00e-4)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.56e-7)" "unprognostic (7.79e-2)" "unprognostic (4.69e-2)" "unprognostic (1.17e-1)" "unprognostic (5.78e-2)" 76.2 93.0 55.5 99.2 57.8 168.8 98.5 58.8 74.1 65.0 56.6 75.3 105.8 76.7 79.7 63.9 62.9 58.5 64.2 54.2 63.2 87.6 84.9 62.1 145.7 60.2 61.0 79.5 56.3 51.5 40.5 88.8 60.7 56.6 87.2 122.7 61.3 59.8 87.2 54.7 99.0 65.9 60.2 82.0 61.7 99.6 58.2 190.4 55.3 68.6 140.4 84.1 55.7 63.6 365.4 156.3 330.0 332.2 115.0 205.8 257.8 275.9 209.1 205.2 207.2 185.8 296.8 544.1 218.7 183.9 440.6 283.0 275.7 231.2 332.1 151.8 209.1 312.8 201.0 208.5 126.1 508.3 294.7 153.9 197.5 163.2 231.2 253.9 281.7 343.2 506.1 263.9 351.7 207.5 489.4 625.9 424.4 311.3 225.1 313.6 303.9 452.3 303.8 201.4 401.1 448.2 230.5 482.6 274.9 345.3 412.4 455.1 212.0 186.0 340.5 222.1 376.8 394.6 596.5 929.3 163.2 422.3 864.3 135.7 85.9 137.7 77.3 116.3 96.9 86.8 114.4 96.1 89.1 77.7 118.4 119.6 92.6 99.2 123.2 72.4 148.3 87.2 55.5 57.8 58.8 74.1 54.2 63.2 60.2 61.0 60.7 60.2 58.2 63.6 139.1 109.0 98.4 16.3 158.5 143.6 93.3 128.0 105.3 101.8 223.8 181.0 124.1 133.0 119.7 64.4 77.2 176.3 138.7 111.2 140.8 167.6 162.2 132.4 215.4 142.6 110.2 306.6 27.4 141.4 362.1 123.6 81.1 129.0 222.0 166.2 145.3 289.2 143.1 50.5 26.8 156.6 107.8 254.9 200.0 41.9 136.4 157.6 104.9 15.0 183.3 155.9 166.9 23.1 35.8 166.3 103.8 98.2 129.1 135.1 112.6 187.4 107.3 132.1 78.9 60.0 110.1 274.5 388.6 112.5 107.8 270.8 155.2 133.1 205.9 110.9 CBX5 "HP1, HP1-ALPHA, HP1Hs-alpha" ENSG00000094916 "Chromobox 5" P45973 12 54230942-54280133 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 102.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016699, CAB017548" Enhanced Enhanced Nucleoplasm NA NA 22000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB017548: AB_2071368, HPA016699: AB_1850627" "unprognostic (1.58e-2)" "unprognostic (7.99e-2)" "unprognostic (1.15e-2)" "unprognostic (5.05e-3)" "unprognostic (3.80e-1)" "unprognostic (4.59e-3)" "unprognostic (2.97e-3)" "unprognostic (6.39e-3)" "unprognostic (2.57e-2)" "unprognostic (1.41e-1)" "unprognostic (4.47e-2)" "unprognostic (1.96e-1)" "unprognostic (2.34e-1)" "unprognostic (1.70e-1)" "unprognostic (1.08e-1)" "unprognostic (6.26e-2)" "unprognostic (8.64e-2)" 8.1 14.0 20.9 12.6 22.4 17.2 13.8 14.1 19.8 10.9 102.6 10.5 7.5 9.7 15.0 9.4 16.0 8.9 20.8 19.3 37.3 17.2 8.0 9.5 18.8 18.7 25.7 18.3 9.9 25.6 19.8 12.3 22.3 11.5 10.9 22.9 8.6 11.8 13.8 17.3 8.7 10.8 24.4 10.7 10.3 25.4 39.1 31.0 23.9 7.7 21.5 7.1 8.4 28.8 33.1 96.3 147.9 68.5 19.3 41.4 34.2 50.1 35.8 41.5 42.8 37.8 102.8 91.0 65.3 49.7 49.4 27.1 106.1 31.2 70.2 144.7 23.1 80.1 108.4 13.5 15.0 42.8 32.8 20.6 20.6 71.0 62.1 46.8 46.4 82.6 92.8 87.4 69.2 57.4 137.2 44.8 118.6 13.9 11.5 133.9 82.7 50.6 43.1 30.0 73.9 113.5 93.6 21.0 10.7 58.0 80.6 71.5 61.4 69.3 59.5 26.6 59.8 22.0 25.9 169.4 44.3 43.0 74.3 1.0 5.4 4.7 6.8 6.0 5.5 11.7 7.3 6.5 9.3 14.3 7.2 6.7 0.8 7.7 8.1 21.8 10.0 4.3 20.9 22.4 14.1 19.8 19.3 37.3 18.7 25.7 22.3 24.4 39.1 28.8 39.4 38.5 50.5 33.3 46.5 46.3 42.6 46.5 40.9 120.5 59.6 55.4 138.2 55.8 47.0 82.8 45.9 58.2 32.1 25.9 105.7 61.7 117.4 53.9 58.9 49.1 27.0 102.2 28.4 59.7 56.5 69.0 22.4 37.0 30.9 81.3 38.6 37.5 38.7 183.4 38.9 37.6 48.8 22.9 35.8 58.3 64.7 25.9 35.6 23.4 44.5 68.6 36.0 46.3 40.0 45.4 14.1 80.5 49.2 41.4 11.6 63.2 79.3 64.1 32.9 70.2 67.9 221.4 80.1 40.8 32.7 26.1 40.5 83.5 44.1 29.8 CCDC167 "C6orf129, dJ153P14.2" ENSG00000198937 "Coiled-coil domain containing 167" Q9P0B6 6 37482938-37499893 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 281.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 145.2;granulocytes: 140.2;T-cells: 423.5" "Cell line enriched" "Detected in all" 9 "U-698: 1553.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045215 Uncertain Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA045215: AB_10962866" "unprognostic (1.82e-1)" "prognostic favorable (7.59e-4)" "unprognostic (6.99e-2)" "unprognostic (3.66e-1)" "unprognostic (2.86e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (2.73e-1)" "unprognostic (7.67e-2)" "unprognostic (3.41e-3)" "unprognostic (2.71e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.71e-7)" "unprognostic (1.57e-1)" "unprognostic (4.06e-1)" "unprognostic (2.44e-1)" "unprognostic (1.95e-1)" 13.2 19.2 49.8 22.8 52.1 28.3 18.5 52.7 54.2 22.1 49.0 19.9 11.6 15.8 45.1 26.6 21.3 11.9 34.9 49.0 51.0 22.0 56.4 13.3 49.5 53.4 51.1 8.5 19.1 27.2 15.0 15.4 52.9 22.8 23.5 14.4 22.6 13.5 21.4 13.4 14.4 31.6 53.0 28.3 15.0 37.7 51.9 90.7 15.1 26.2 70.3 16.8 17.1 57.7 27.2 61.9 137.1 95.4 37.4 65.5 50.4 31.6 25.8 48.8 54.5 66.1 39.5 146.9 69.4 54.8 92.1 20.7 90.4 74.1 49.7 122.9 166.9 69.7 25.3 168.7 39.1 68.4 26.4 30.7 153.4 52.1 47.4 34.2 154.0 150.2 44.1 123.1 85.1 90.2 129.1 56.6 8.0 76.7 39.3 79.0 48.4 108.9 66.3 53.6 93.3 109.6 47.1 46.0 74.3 119.3 50.1 70.3 38.5 31.8 61.6 17.8 32.5 89.3 97.1 1553.2 30.8 147.9 90.8 34.9 32.6 140.2 140.0 35.6 169.2 145.2 230.0 177.9 56.3 122.6 105.5 99.7 10.0 55.8 29.5 35.8 423.5 165.8 49.8 52.1 52.7 54.2 49.0 51.0 53.4 51.1 52.9 53.0 51.9 57.7 18.6 6.4 10.3 5.2 50.6 14.1 26.5 62.1 10.8 9.4 22.4 30.4 50.0 24.3 36.0 14.7 8.4 67.1 33.4 31.8 31.3 69.3 108.2 19.1 31.8 23.4 25.2 86.7 2.2 50.4 108.7 26.4 16.3 31.7 15.2 61.9 25.0 141.9 89.8 15.2 3.2 56.2 48.8 18.8 31.4 281.6 13.1 23.8 55.2 1.9 25.2 56.5 29.9 2.0 7.3 57.9 13.6 18.8 100.2 35.9 10.8 89.0 30.3 11.8 6.6 14.0 28.7 96.8 118.9 26.2 15.2 29.7 59.7 38.1 36.6 31.9 CCDC18 NY-SAR-41 ENSG00000122483 "Coiled-coil domain containing 18" Q5T9S5 1 93179919-93278730 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.6;lymphoid tissue: 8.9;testis: 9.5" "Cell type enhanced" "Detected in many" "Early spermatids: 50.5;Spermatocytes: 137.2;Spermatogonia: 47.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028035 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA028035: AB_10601795" "unprognostic (8.79e-2)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (1.49e-4)" "unprognostic (4.36e-4)" "unprognostic (1.02e-1)" "unprognostic (1.44e-2)" "unprognostic (3.41e-2)" "unprognostic (1.63e-2)" "unprognostic (3.50e-2)" "unprognostic (3.64e-13)" "unprognostic (4.94e-2)" "unprognostic (9.19e-2)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" 1.9 1.0 1.3 4.3 1.4 10.6 1.1 1.6 1.1 1.0 1.0 1.9 1.7 1.2 0.8 1.6 0.7 1.1 1.0 1.1 1.3 0.6 2.0 1.7 8.9 1.4 1.3 1.3 0.4 0.3 0.8 1.3 1.4 0.6 2.7 0.6 0.7 0.3 2.0 2.1 1.6 1.2 1.1 3.5 1.5 9.5 1.3 6.5 0.7 0.9 5.9 1.6 0.9 1.4 24.8 8.1 18.7 5.9 4.5 4.7 9.7 15.1 7.9 15.1 15.3 4.3 8.3 31.9 8.2 8.1 14.7 11.5 8.2 11.8 21.9 15.9 10.7 21.9 18.5 7.6 1.6 23.1 9.8 3.1 1.0 11.5 11.1 4.2 10.0 14.0 23.8 23.9 20.4 3.5 11.1 9.3 17.1 6.7 10.0 14.0 22.3 9.4 7.4 10.9 8.2 5.2 21.4 10.8 6.1 8.3 5.1 13.3 7.7 17.7 12.4 11.5 17.5 10.2 14.5 18.8 3.7 20.1 4.8 5.1 3.6 5.8 2.3 4.1 2.7 10.2 2.1 2.2 1.7 11.6 1.7 1.9 6.0 1.2 3.8 12.5 2.5 0.5 1.3 1.4 1.6 1.1 1.1 1.3 1.4 1.3 1.4 1.1 1.3 1.4 5.0 19.2 9.6 16.6 17.6 4.1 7.9 4.5 8.0 2.4 3.8 4.2 9.5 0.0 3.6 3.7 4.2 5.7 18.4 3.6 0.0 2.3 50.5 6.6 7.6 4.6 0.0 40.2 13.2 2.9 6.7 8.8 8.2 6.1 19.0 13.5 5.0 4.5 8.2 1.7 12.6 3.2 6.1 14.2 10.4 16.3 6.2 17.5 3.6 15.0 12.9 0.7 7.2 7.5 15.7 2.0 4.4 6.4 22.7 4.6 2.1 1.5 5.6 0.7 6.6 9.8 8.1 137.2 47.7 8.2 7.2 2.9 15.7 5.1 6.9 8.9 CCDC34 "L15, NY-REN-41, RAMA3" ENSG00000109881 "Coiled-coil domain containing 34" Q96HJ3 11 27330827-27363234 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 48.8" "Cell type enhanced" "Detected in many" "Early spermatids: 383.4;Endometrial ciliated cells: 156.1;Spermatocytes: 336.8;Spermatogonia: 218.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 159.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037574 Uncertain Approved "Nuclear membrane,Nucleoli fibrillar center" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane, Nucleoli fibrillar center" "HPA037574: AB_10795136" "unprognostic (8.23e-3)" "unprognostic (1.09e-3)" "unprognostic (7.47e-2)" "unprognostic (1.65e-1)" "unprognostic (1.46e-2)" "unprognostic (6.40e-2)" "prognostic unfavorable (1.32e-7)" "unprognostic (9.09e-2)" "unprognostic (1.34e-3)" "prognostic favorable (8.52e-4)" "unprognostic (1.16e-1)" "unprognostic (4.06e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (4.97e-2)" "unprognostic (4.14e-2)" "unprognostic (1.64e-2)" "unprognostic (6.11e-2)" 3.8 5.3 16.1 5.6 15.9 13.7 11.2 13.8 32.8 4.4 16.7 8.8 10.7 4.9 11.3 5.5 12.5 3.4 3.4 15.9 15.4 5.0 4.6 2.3 6.5 15.2 14.9 9.7 4.3 8.1 5.5 5.1 15.4 5.4 10.1 6.2 4.1 4.3 3.1 6.5 8.9 3.5 14.3 4.4 9.3 48.8 15.9 15.8 5.6 3.4 8.8 3.3 3.5 14.8 46.1 50.4 41.6 44.7 7.5 17.6 30.8 29.5 11.1 29.8 28.8 28.2 8.3 49.4 20.2 15.8 42.7 40.2 41.9 18.2 54.3 19.5 58.2 39.4 62.6 74.1 3.8 40.6 15.4 5.7 13.4 26.0 12.5 13.2 23.3 70.1 39.0 15.9 32.1 32.6 79.3 63.1 42.9 31.4 44.1 74.8 152.8 7.4 12.8 15.2 32.2 42.2 44.0 19.5 20.8 23.4 52.8 21.4 11.1 47.8 45.2 91.3 69.4 153.2 159.4 34.8 44.5 2.0 42.7 0.0 0.2 0.4 3.1 1.0 3.7 3.4 3.9 4.2 1.0 4.0 4.5 2.8 0.0 3.7 3.8 2.3 6.7 1.1 16.1 15.9 13.8 32.8 15.9 15.4 15.2 14.9 15.4 14.3 15.9 14.8 5.1 0.0 1.7 4.9 10.1 22.8 22.9 33.2 13.1 10.3 71.4 73.3 9.2 27.1 20.6 23.9 12.5 45.5 3.4 41.0 19.6 14.1 383.4 156.1 12.5 11.1 21.6 91.3 11.5 12.3 25.1 17.2 31.1 15.3 7.0 30.9 10.0 16.0 22.0 3.3 7.5 40.5 18.3 8.9 8.4 82.4 21.5 5.7 14.2 0.0 4.7 26.6 7.2 1.0 1.2 5.5 12.1 20.7 13.9 10.3 6.2 17.6 101.5 20.6 6.6 11.6 18.3 336.8 218.8 33.2 20.6 16.1 9.1 10.3 71.2 15.5 CCDC77 MGC13183 ENSG00000120647 "Coiled-coil domain containing 77" Q9BR77 12 389273-442642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038854 Approved Approved "Nuclear membrane" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "HPA038854: AB_10673121" "unprognostic (3.25e-1)" "unprognostic (2.32e-1)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (7.26e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.11e-7)" "unprognostic (2.54e-2)" "unprognostic (3.41e-3)" "unprognostic (2.89e-1)" "unprognostic (3.82e-1)" "unprognostic (2.62e-1)" "unprognostic (4.11e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-1)" "unprognostic (3.19e-2)" "unprognostic (4.41e-3)" 3.4 5.0 3.1 6.2 4.9 4.6 4.5 3.1 4.9 3.6 1.8 4.1 4.6 5.0 2.2 4.1 3.8 3.2 3.1 3.9 4.6 3.8 3.4 3.9 6.8 4.5 4.1 5.2 2.5 2.3 2.4 3.6 4.3 3.5 4.7 3.4 3.0 2.6 4.7 5.2 3.6 3.4 2.8 4.8 3.3 12.5 3.9 9.7 4.0 3.2 6.2 3.1 3.6 7.7 10.0 13.2 28.7 18.9 9.5 8.1 29.4 24.7 11.6 23.3 37.4 13.4 17.1 23.8 5.9 9.8 13.6 13.6 20.5 7.2 25.0 52.0 20.1 26.9 26.5 17.8 5.5 22.2 12.9 6.5 4.3 21.9 13.5 14.0 15.6 22.7 22.4 24.2 23.9 6.0 21.6 15.7 57.0 13.8 9.9 24.4 51.8 14.7 8.7 7.3 8.2 21.1 24.5 9.4 12.9 42.4 7.4 16.7 14.8 11.6 22.5 20.6 29.0 6.8 13.9 29.8 15.7 22.0 20.3 2.5 4.5 3.9 4.7 6.4 4.9 5.9 4.3 5.2 4.8 8.1 3.0 4.5 3.4 6.2 8.1 5.2 3.3 3.1 3.1 4.9 3.1 4.9 3.9 4.6 4.5 4.1 4.3 2.8 3.9 7.7 4.6 0.0 6.2 2.6 9.4 4.1 3.6 3.5 3.4 3.1 4.1 4.4 3.7 2.8 4.4 3.7 6.2 6.8 8.6 2.9 7.9 3.2 24.2 5.6 5.5 4.4 2.4 5.0 8.1 2.0 8.0 4.7 6.6 4.5 7.0 8.1 3.6 2.3 5.5 1.7 7.9 4.5 8.2 6.6 2.9 15.3 4.1 5.5 1.8 3.7 6.0 6.5 8.2 8.0 13.7 2.0 5.9 4.5 7.0 2.6 2.0 3.4 5.4 5.5 6.6 7.4 4.3 22.3 18.0 6.7 3.8 5.6 6.6 4.4 4.1 2.2 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CCNE2 CYCE2 ENSG00000175305 "Cyclin E2" O96020 8 94879770-94896678 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.6;Oligodendrocytes: 34.5;Spermatocytes: 77.7;Spermatogonia: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 101.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007825, CAB019374" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB007825: AB_598148, CAB019374: " "unprognostic (1.80e-2)" "unprognostic (4.81e-2)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (2.36e-1)" "prognostic favorable (5.87e-4)" "unprognostic (8.37e-4)" "prognostic unfavorable (8.77e-4)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.64e-2)" "unprognostic (1.04e-2)" "unprognostic (7.01e-12)" "unprognostic (1.81e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.03e-1)" 2.0 0.6 3.7 6.9 8.3 37.0 2.2 9.0 7.7 1.7 0.3 5.4 3.6 1.8 0.1 4.7 0.6 2.4 1.4 3.2 5.4 0.5 2.3 1.8 10.9 9.9 8.1 1.5 1.8 0.5 0.6 4.3 8.8 1.2 5.7 5.2 1.8 0.2 0.7 5.9 4.3 2.2 7.4 2.3 4.0 14.5 8.0 15.1 1.7 0.7 9.6 2.1 1.5 13.4 47.2 6.2 24.0 15.0 2.9 5.4 16.5 47.3 16.6 29.4 28.9 11.3 20.6 24.5 31.4 20.3 9.1 24.4 19.4 17.5 39.5 17.4 17.5 49.5 26.6 4.2 0.2 20.2 29.0 1.4 1.1 21.4 2.1 6.4 15.5 30.1 21.7 101.5 42.5 14.2 77.8 9.7 8.1 37.4 14.1 54.1 41.7 11.7 8.1 26.4 34.8 14.5 31.8 8.4 5.9 3.0 42.0 21.2 13.0 30.7 20.2 22.9 42.8 19.1 21.1 59.3 24.8 36.1 23.1 0.0 0.2 0.1 0.8 0.2 0.3 0.3 1.1 1.3 0.7 1.0 0.3 0.6 0.6 1.5 0.1 0.0 5.2 0.6 3.7 8.3 9.0 7.7 3.2 5.4 9.9 8.1 8.8 7.4 8.0 13.4 7.5 6.4 1.7 0.7 3.0 4.2 1.6 2.3 6.8 2.9 5.9 8.9 2.5 0.0 1.9 1.8 6.2 7.2 7.2 12.3 0.0 0.2 6.9 1.3 2.7 3.5 0.0 33.6 2.3 0.2 7.8 2.6 4.1 2.9 0.0 2.1 2.5 1.3 4.4 8.4 2.6 4.0 0.0 2.5 1.9 9.0 1.2 4.8 0.0 0.0 0.0 1.0 1.0 1.5 34.5 0.2 2.4 0.4 14.6 1.1 6.3 0.1 1.1 4.7 6.6 2.6 4.3 77.7 26.2 9.5 3.8 1.9 7.5 1.2 3.3 0.8 CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060596, HPA070495, HPA071600" Enhanced Supported Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA060596: AB_2684329, HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-3)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (7.46e-7)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-1)" 1.4 1.0 2.5 3.8 2.1 7.3 1.9 2.9 2.7 1.3 0.0 2.0 2.8 0.8 2.0 4.0 0.8 0.8 0.6 2.4 2.0 0.6 0.7 1.0 7.4 1.5 2.0 1.0 0.8 0.5 0.8 2.5 1.3 1.6 2.0 0.8 2.1 1.1 1.3 4.8 2.1 1.1 0.8 2.2 1.6 2.7 2.6 15.1 0.7 1.3 9.6 1.7 1.5 1.7 21.0 32.4 31.3 28.9 2.2 2.9 23.8 24.1 12.2 34.2 26.1 64.6 25.6 42.3 8.0 14.1 10.2 33.1 52.2 19.6 16.4 30.9 23.4 46.1 35.3 20.4 2.3 30.4 30.7 2.0 2.5 24.1 11.7 4.4 25.5 36.5 52.0 28.5 17.6 45.6 46.1 25.0 31.2 22.6 13.2 76.2 35.1 39.5 9.5 9.3 29.8 17.0 36.0 32.8 6.4 15.6 34.3 16.6 18.1 19.1 46.7 13.5 27.1 16.4 20.9 74.5 5.6 31.8 26.9 0.0 0.3 0.0 0.7 0.1 0.4 0.6 0.4 0.9 0.1 0.4 0.3 0.4 0.0 1.3 0.3 0.5 0.5 0.6 2.5 2.1 2.9 2.7 2.4 2.0 1.5 2.0 1.3 0.8 2.6 1.7 0.9 0.0 3.9 3.3 2.7 2.8 2.7 1.4 6.2 5.3 2.4 2.0 1.9 0.0 1.6 1.8 12.5 7.0 3.7 2.4 0.0 1.2 0.9 1.0 2.7 2.2 1.2 37.5 5.7 0.6 12.2 2.2 5.6 1.0 1.3 8.9 2.5 0.9 6.1 8.4 5.6 2.6 4.1 2.4 1.6 0.0 1.8 1.5 5.4 0.0 0.8 0.9 2.1 1.0 1.0 1.1 0.3 2.6 7.2 1.9 0.9 0.2 0.3 1.6 0.0 0.8 2.7 3.9 5.7 3.5 1.1 1.9 3.4 1.7 4.7 1.6 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 52.6;testis: 49.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.0;Early spermatids: 135.0;Erythroid cells: 96.0;Extravillous trophoblasts: 146.2;Spermatocytes: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.5;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.5;T-cells: 11.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.6 1.5 0.6 16.2 1.1 53.9 5.2 0.8 1.3 3.5 0.4 14.8 13.7 2.3 2.5 27.2 1.7 1.2 0.9 0.7 1.1 2.3 1.7 2.5 32.6 1.3 1.1 0.7 0.6 0.2 0.3 9.7 1.1 0.8 16.0 0.2 4.4 0.7 0.3 11.3 12.2 7.3 0.8 11.7 7.0 49.1 1.7 52.6 1.7 0.2 50.8 3.3 7.0 1.3 311.9 148.2 202.8 133.4 6.9 17.6 193.5 140.3 125.0 400.0 211.4 234.5 250.9 178.3 80.1 130.1 140.6 212.8 225.3 267.9 331.5 140.8 165.6 261.4 143.6 147.3 2.1 184.3 91.4 6.0 12.4 278.2 249.6 35.1 172.2 167.5 120.2 119.3 184.0 120.4 179.2 113.5 257.2 147.0 196.9 255.8 277.9 112.9 98.5 81.3 119.2 58.9 248.1 165.8 76.6 154.9 116.3 231.7 90.2 118.9 276.2 133.7 445.0 90.6 86.7 185.7 85.2 227.6 181.6 0.0 0.1 0.0 0.3 0.0 0.0 4.2 3.2 3.5 0.9 0.9 0.1 0.3 0.7 9.5 0.0 0.2 11.6 2.8 0.6 1.1 0.8 1.3 0.7 1.1 1.3 1.1 1.1 0.8 1.7 1.3 2.1 0.0 1.1 0.0 12.2 10.5 3.8 17.6 6.2 0.5 6.4 9.7 0.7 1.5 4.8 0.0 0.0 65.0 2.8 16.9 0.0 2.2 135.0 14.6 2.4 4.5 0.0 96.0 0.2 0.4 146.2 9.3 11.7 4.6 0.0 46.5 7.9 1.3 37.4 0.0 0.0 18.5 24.4 6.2 7.5 18.5 2.8 9.3 0.0 0.0 1.8 0.3 0.0 0.0 1.6 0.7 0.5 1.9 34.4 2.7 3.2 3.1 8.3 2.9 0.0 1.0 25.4 126.5 39.8 47.3 8.4 10.7 5.1 1.6 37.5 7.4 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 8.9;testis: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 42.1;Spermatocytes: 53.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 0.2 0.2 0.2 2.1 0.2 5.8 0.7 0.3 0.3 0.3 0.2 3.4 3.0 0.4 0.2 1.4 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.3 3.2 0.2 0.3 0.0 0.4 0.1 0.1 1.2 0.2 0.2 4.1 0.1 0.3 0.1 0.0 1.4 3.0 0.8 0.1 0.9 1.1 18.1 0.2 8.9 0.1 0.0 4.6 0.5 0.5 0.2 27.9 11.0 38.4 28.9 0.9 3.6 9.9 16.4 17.5 36.2 50.3 27.3 52.8 13.3 13.8 10.1 40.5 14.9 31.7 25.9 34.9 11.1 21.5 9.6 15.0 21.2 0.3 6.3 10.0 0.8 0.9 22.0 18.0 3.8 24.6 28.9 14.8 24.2 22.9 15.5 19.3 16.7 9.7 22.3 12.2 11.9 34.2 15.0 6.4 8.4 19.2 11.9 36.8 11.0 16.9 32.6 18.7 13.9 7.2 19.9 16.8 13.9 26.5 15.0 13.4 13.0 8.3 14.3 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.0 0.0 1.3 0.9 0.6 0.3 1.1 1.8 0.0 0.9 0.8 0.3 0.0 0.2 0.0 0.0 5.0 0.5 1.8 0.0 0.1 41.4 0.4 0.9 0.6 0.0 9.5 1.3 0.0 6.9 1.1 3.6 1.2 0.0 5.5 1.4 0.4 2.7 0.0 1.0 3.9 2.0 0.6 0.5 42.1 1.8 1.2 0.0 1.0 0.6 0.0 0.0 1.0 0.3 0.0 1.4 0.4 4.5 0.3 0.9 0.1 0.1 0.0 0.0 0.2 0.9 53.6 13.0 4.3 0.4 1.4 0.6 0.2 4.9 0.6 CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;lymphoid tissue: 20.4;testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Erythroid cells: 29.7;Spermatocytes: 72.3;Spermatogonia: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "K-562: 370.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "CAB009459: AB_2078507, HPA000614: AB_1078487" "unprognostic (5.56e-2)" "unprognostic (6.12e-3)" "unprognostic (1.17e-3)" "unprognostic (3.42e-3)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "prognostic unfavorable (6.95e-6)" "unprognostic (6.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (8.94e-4)" "unprognostic (7.28e-2)" "unprognostic (0.00e+0)" "unprognostic (7.62e-3)" "unprognostic (2.02e-1)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" 0.5 0.5 0.7 6.2 0.5 25.4 1.5 0.2 0.2 1.1 0.4 4.6 3.5 0.9 0.3 5.3 0.4 0.5 0.3 0.2 0.4 0.3 1.2 0.9 11.3 0.5 0.4 0.2 0.2 0.2 0.1 3.2 0.5 0.4 6.0 0.1 0.9 0.2 0.1 3.3 3.1 1.8 0.2 2.8 2.6 23.4 1.1 20.4 0.3 0.0 11.8 1.9 1.7 0.3 57.4 42.2 56.4 42.9 2.0 5.6 24.4 65.4 31.6 75.5 75.5 35.8 30.5 62.2 23.2 21.0 28.9 51.9 58.2 45.9 59.5 72.3 96.3 82.8 50.1 41.3 3.1 125.0 43.7 1.3 2.4 57.9 26.0 7.0 38.8 63.0 370.6 73.3 44.8 77.2 98.1 56.5 16.7 106.2 34.4 77.1 95.5 26.5 16.9 49.3 72.1 37.0 38.1 40.0 12.0 21.7 26.2 51.0 15.0 60.0 91.6 46.0 62.8 24.6 46.8 67.5 30.1 58.9 82.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.2 0.1 0.5 0.5 0.1 0.3 0.9 0.6 0.7 0.5 0.2 0.2 0.2 0.4 0.5 0.4 0.5 0.2 1.1 0.3 0.2 0.0 0.0 0.0 1.9 2.7 1.7 3.7 0.0 0.0 0.7 0.8 0.4 0.0 0.5 0.0 0.0 11.9 1.4 1.9 0.0 0.8 120.5 0.9 0.7 1.2 0.0 29.7 0.1 0.0 19.8 2.3 1.5 1.0 0.0 5.5 3.6 0.0 7.2 0.0 0.1 1.2 4.1 0.6 1.0 14.4 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.7 12.6 0.2 0.4 0.0 0.3 0.0 6.6 1.5 13.9 72.3 50.7 3.3 1.8 4.9 1.2 0.8 5.1 2.5 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25459199-25507911 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.5;lymphoid tissue: 11.4;testis: 19.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.3;Early spermatids: 49.9;Erythroid cells: 19.0;Late spermatids: 24.2;Spermatocytes: 66.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA026293: AB_1846384, HPA030049: AB_10600862" "unprognostic (2.12e-1)" "unprognostic (4.75e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.92e-2)" "unprognostic (9.69e-2)" "unprognostic (3.56e-2)" "unprognostic (2.50e-5)" "unprognostic (1.47e-3)" "unprognostic (6.06e-2)" "unprognostic (2.91e-3)" "unprognostic (1.32e-3)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.30e-14)" "unprognostic (1.36e-2)" "unprognostic (4.02e-1)" "unprognostic (1.91e-1)" "unprognostic (5.30e-2)" 0.2 0.0 0.0 2.6 0.0 6.5 0.6 0.1 0.0 0.2 0.1 1.9 1.6 0.3 0.0 1.4 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.2 5.3 0.2 0.2 0.0 0.0 0.0 0.0 1.2 0.2 0.1 2.2 0.1 0.2 0.0 0.0 1.1 1.8 0.8 0.0 0.8 0.9 19.4 0.3 11.4 0.1 0.1 6.7 0.6 0.3 0.1 36.5 30.2 29.4 24.2 2.3 4.5 20.2 37.7 22.6 32.9 32.4 25.7 15.8 42.6 16.0 16.2 34.6 31.6 42.9 20.0 48.5 16.2 12.0 43.2 22.4 15.2 0.6 18.4 19.4 2.5 1.0 23.5 15.8 3.3 24.5 24.5 33.6 45.8 30.6 13.9 54.5 8.7 31.0 24.1 14.5 26.3 33.4 15.2 9.2 18.7 12.0 13.3 33.3 16.1 14.3 14.7 17.4 9.4 16.6 23.9 39.3 44.7 35.6 7.1 16.5 44.4 17.7 24.3 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.1 0.2 0.0 1.1 0.0 2.7 1.1 0.5 1.7 0.0 0.7 0.9 0.8 23.3 0.0 0.2 0.0 0.0 7.2 0.5 1.8 0.0 0.2 49.9 0.8 1.2 1.1 0.0 19.0 0.2 0.0 13.4 2.5 4.1 1.4 0.0 8.8 1.1 0.1 4.1 0.0 0.1 1.3 0.0 2.9 0.6 24.2 1.2 2.1 0.0 0.0 0.6 0.1 2.1 0.5 0.6 0.2 0.1 0.0 15.8 0.5 0.5 1.2 0.9 0.5 13.1 0.1 2.1 66.6 27.8 10.7 0.9 1.6 2.9 1.3 3.6 0.5 CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.5;retina: 66.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Erythroid cells: 46.5;Extravillous trophoblasts: 74.1;Proximal enterocytes: 65.5;Spermatocytes: 71.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026587 Approved Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA026587: AB_1846386" "unprognostic (3.05e-1)" "unprognostic (1.32e-1)" "unprognostic (9.85e-2)" "unprognostic (1.63e-2)" "unprognostic (2.42e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.51e-5)" "prognostic unfavorable (9.77e-5)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-3)" "unprognostic (8.81e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (4.94e-2)" 1.2 2.6 0.7 7.3 0.5 16.0 1.2 1.0 1.0 4.4 0.3 6.1 20.7 2.9 0.4 9.0 1.9 1.1 2.8 0.6 0.6 1.6 1.6 1.7 17.2 0.7 0.7 4.6 1.1 0.4 8.6 4.7 0.6 3.1 7.8 66.3 2.5 0.3 0.5 6.3 18.5 3.0 0.4 4.6 3.2 21.4 0.6 30.5 1.8 0.2 23.4 2.2 4.0 0.5 106.8 88.8 81.0 45.1 4.3 6.8 95.0 71.7 46.4 119.5 83.3 142.7 86.9 64.9 8.6 54.9 86.9 71.0 53.3 55.0 117.0 97.2 60.9 56.8 58.9 81.7 0.5 41.3 47.2 3.1 3.9 63.0 34.6 27.9 50.9 44.2 47.8 36.4 116.7 94.1 60.0 46.0 86.2 75.8 62.3 57.6 68.5 34.3 40.2 36.4 12.2 23.6 61.8 53.5 18.7 87.0 21.9 38.6 22.3 52.6 67.2 35.0 117.2 19.7 21.5 104.2 25.4 53.6 92.0 0.0 0.2 0.0 0.1 0.1 0.3 0.7 0.7 0.8 0.2 0.2 0.2 0.4 0.2 0.4 0.3 1.1 4.3 0.5 0.7 0.5 1.0 1.0 0.6 0.6 0.7 0.7 0.6 0.4 0.6 0.5 0.7 0.0 0.5 0.7 4.1 2.9 1.7 5.0 2.2 12.3 1.9 2.5 1.2 1.5 1.1 0.0 56.3 29.5 0.9 6.9 0.0 1.1 12.4 1.8 2.3 1.7 1.2 46.5 0.5 0.4 74.1 5.2 4.6 2.3 4.5 15.2 3.9 1.6 19.3 6.7 0.6 11.9 4.1 4.0 3.1 6.8 1.8 3.5 0.0 1.0 1.1 1.1 1.0 0.5 0.5 0.4 4.0 0.4 19.2 1.4 65.5 0.9 0.4 18.0 6.6 0.5 8.3 71.5 14.8 12.6 1.8 8.5 4.6 1.4 17.4 2.6 CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.4;lymphoid tissue: 27.6;testis: 37.8" "Cell type enhanced" "Detected in many" "Early spermatids: 56.5;Extravillous trophoblasts: 38.3;Late spermatids: 116.9;Spermatocytes: 50.4;Spermatogonia: 31.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "NK-cell: 2.8;T-reg: 2.0" "Group enriched" "Detected in many" 5 "NK-cells: 2.8;T-cells: 2.0" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023691: AB_1846392, HPA076007: " "unprognostic (3.14e-2)" "unprognostic (4.20e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.15e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.21e-6)" "unprognostic (1.41e-3)" "unprognostic (7.55e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (8.72e-6)" "unprognostic (2.16e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.55e-3)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (8.97e-2)" 1.4 1.2 1.3 10.5 1.3 53.4 2.0 0.8 1.8 1.9 0.9 6.8 5.8 1.3 0.3 9.3 0.9 0.9 0.9 1.5 0.9 0.9 1.3 1.9 17.0 1.6 1.3 0.6 0.7 0.4 0.5 6.5 1.6 0.8 7.7 0.5 1.4 0.5 0.6 4.2 5.8 3.1 0.8 6.6 3.1 37.8 1.8 27.6 0.6 0.4 16.2 2.2 2.8 1.3 131.7 74.9 67.2 57.3 4.5 7.3 57.8 92.7 37.4 103.6 81.5 77.7 75.4 121.3 52.3 29.4 120.8 87.9 110.3 49.5 98.6 122.0 52.2 107.7 54.4 64.1 0.4 116.8 81.8 2.5 4.5 96.3 44.0 10.8 32.6 138.4 126.6 206.6 63.5 109.2 164.7 116.9 107.8 63.0 92.4 140.4 76.8 111.9 21.2 49.6 89.1 68.4 59.3 80.7 62.8 41.6 104.7 54.7 19.9 92.7 97.2 99.5 101.7 106.9 187.8 195.4 37.2 69.5 97.4 0.0 0.1 0.2 0.4 0.0 0.0 0.3 0.5 0.3 0.4 0.5 0.0 0.3 0.0 2.8 0.3 0.3 2.0 0.7 1.3 1.3 0.8 1.8 1.5 0.9 1.6 1.3 1.6 0.8 1.8 1.3 0.9 0.0 0.5 0.0 4.6 3.8 1.2 1.3 0.6 0.6 2.3 4.4 1.0 0.0 0.8 0.0 2.1 19.7 2.2 4.6 1.9 0.8 56.5 1.1 1.5 2.3 0.0 21.8 1.1 0.8 38.3 3.5 3.1 1.5 3.8 14.5 1.1 0.0 11.7 1.7 0.6 4.7 2.0 2.8 1.5 116.9 2.8 1.7 0.0 1.0 2.1 0.9 2.1 0.0 0.6 0.6 0.1 1.5 16.2 1.1 1.1 0.6 0.4 0.2 0.0 0.5 2.7 50.4 31.1 7.1 1.0 3.7 4.2 1.9 9.4 1.6 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;lymphoid tissue: 38.8;testis: 22.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 34.1;Extravillous trophoblasts: 26.0;Spermatocytes: 76.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.0 1.1 0.7 7.9 1.0 33.5 2.0 0.2 0.9 1.7 0.0 9.4 8.3 1.3 1.8 9.2 1.0 1.1 0.6 0.5 0.4 0.8 1.3 1.5 19.5 0.6 0.4 0.6 0.8 0.5 0.6 4.4 0.5 0.7 11.3 1.9 1.8 0.5 0.3 6.3 7.3 2.8 0.3 4.9 4.9 22.5 0.6 38.8 0.6 0.5 22.7 2.0 2.9 0.7 108.5 45.5 84.4 62.1 3.6 7.0 57.2 79.6 39.5 137.2 96.6 71.9 78.8 130.2 31.5 50.5 54.5 59.4 97.8 52.4 141.9 86.8 44.9 116.8 49.2 57.3 0.8 113.8 58.4 2.8 3.8 77.1 67.3 15.3 60.9 91.1 100.7 135.6 99.1 47.7 106.1 68.9 98.8 61.7 62.8 102.2 115.6 74.4 31.0 43.8 75.4 33.3 87.5 40.6 52.4 71.7 60.1 42.4 37.3 67.8 70.6 39.2 126.0 91.4 128.1 176.3 31.6 104.7 79.6 0.0 0.7 1.3 1.5 1.6 2.8 1.7 3.6 2.2 0.7 1.4 1.1 2.3 3.0 4.1 3.9 1.2 5.9 1.7 0.7 1.0 0.2 0.9 0.5 0.4 0.6 0.4 0.5 0.3 0.6 0.7 0.8 0.0 0.5 1.3 4.8 3.3 0.8 2.4 1.8 1.3 1.9 1.5 0.7 2.8 0.4 0.0 0.0 17.1 1.9 12.4 0.0 1.2 1.0 1.7 1.6 1.9 3.6 34.1 1.2 0.6 26.0 2.9 6.6 2.5 0.0 12.0 3.6 1.0 11.6 1.7 0.9 8.2 2.0 3.5 1.9 2.8 1.5 3.7 1.8 0.0 1.6 0.1 2.1 0.5 0.9 2.4 4.0 1.2 15.8 1.3 1.9 0.6 4.7 1.0 19.7 0.2 6.3 76.8 42.0 17.1 2.7 2.9 5.5 1.2 13.2 1.2 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.2;lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.9;Erythroid cells: 209.6;Extravillous trophoblasts: 144.6;Spermatocytes: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.2;T-reg: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003387, CAB003799, CAB079974" Enhanced Supported Nucleoplasm,Cytosol NA Yes 51000 "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB003799: AB_344898, CAB079974: , HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favorable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (1.10e-6)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 3.8 1.8 0.9 17.0 1.0 53.2 7.4 0.9 1.5 5.2 0.9 17.6 16.3 7.1 12.2 17.5 3.7 4.3 1.4 0.9 1.0 3.1 3.2 4.7 40.6 1.2 1.2 2.3 0.8 2.5 4.1 19.4 1.1 1.7 20.8 1.3 3.2 5.2 1.4 13.2 14.5 8.0 0.9 9.0 10.1 25.1 1.4 74.0 3.6 2.2 47.5 7.1 6.9 1.0 249.9 93.5 241.1 96.0 15.4 23.6 99.0 183.8 132.7 218.8 209.0 218.9 213.7 226.2 69.6 50.6 79.6 149.9 166.2 106.8 225.8 162.3 121.1 119.4 84.4 128.1 2.8 184.5 117.6 4.7 10.4 142.1 137.0 49.6 133.3 146.2 185.1 270.3 246.9 66.3 234.0 131.1 106.6 149.3 193.1 199.7 224.5 111.3 84.3 81.4 112.7 98.7 123.5 184.9 96.3 130.0 199.9 111.5 55.4 92.8 197.9 99.1 255.8 104.9 180.8 205.6 79.9 203.5 117.6 0.0 0.0 0.0 0.3 0.1 0.2 0.5 0.7 1.3 0.3 0.4 0.2 0.7 0.0 3.2 0.1 0.9 3.4 0.9 0.9 1.0 0.9 1.5 0.9 1.0 1.2 1.2 1.1 0.9 1.4 1.0 7.7 0.0 3.2 0.3 7.1 39.8 5.4 29.9 2.8 1.1 5.3 6.1 0.8 0.0 10.2 18.4 0.0 80.9 3.6 8.9 3.9 0.8 18.7 10.8 6.2 10.5 3.0 209.6 0.4 0.0 144.6 13.3 13.3 9.4 0.0 51.5 7.5 1.3 57.2 0.0 0.2 14.6 30.5 20.5 18.1 10.4 2.1 16.5 1.8 1.9 1.0 1.0 3.1 0.0 0.1 0.4 0.7 0.7 32.1 4.3 2.2 3.0 17.6 0.7 0.0 0.5 24.6 110.0 39.6 33.8 18.6 22.0 10.3 2.1 26.6 10.4 CDK5RAP2 "C48, CEP215, FLJ10867, MCPH3" ENSG00000136861 "CDK5 regulatory subunit associated protein 2" Q96SN8 9 120388869-120580170 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035820, HPA035821, HPA046529, CAB079753" Approved Enhanced "Cell Junctions,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Cell Junctions" "CAB079753: AB_2665827, HPA035820: AB_10671939, HPA035821: , HPA046529: AB_2679688" "unprognostic (7.72e-2)" "unprognostic (2.04e-2)" "unprognostic (2.84e-2)" "unprognostic (4.48e-2)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" "unprognostic (6.70e-3)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (7.36e-2)" "unprognostic (2.26e-2)" "unprognostic (1.88e-1)" "unprognostic (4.94e-2)" "unprognostic (2.36e-1)" "unprognostic (3.33e-2)" "unprognostic (7.41e-2)" 10.6 11.7 12.4 9.8 18.0 24.4 14.4 14.1 12.7 14.2 20.6 15.1 5.6 11.5 7.7 12.1 11.9 9.2 17.6 12.5 12.9 8.0 15.7 10.6 15.1 15.4 16.2 17.1 9.5 13.3 12.2 8.6 15.1 13.7 8.6 12.9 22.2 10.5 47.9 16.0 11.0 10.4 13.6 11.5 12.9 20.8 14.9 20.9 11.6 29.6 14.7 12.5 11.1 17.2 19.6 33.8 45.9 27.8 19.3 28.4 24.6 24.6 18.9 27.3 25.4 26.8 25.1 36.3 11.1 24.3 18.7 42.1 36.5 28.3 26.1 29.3 14.7 31.0 62.1 47.7 18.1 38.5 19.9 51.4 18.5 24.3 31.8 20.6 24.1 43.0 29.2 30.6 36.4 44.2 41.8 24.7 42.6 41.5 25.3 40.3 54.5 17.1 19.5 15.4 29.9 34.3 42.9 23.3 28.8 19.7 54.6 26.3 16.1 23.6 25.7 28.0 28.4 22.2 33.4 39.7 24.6 24.4 50.8 15.7 1.7 3.0 3.4 1.7 3.3 5.0 3.2 3.2 1.0 5.8 2.6 2.7 2.4 4.0 4.7 2.2 2.9 1.8 12.4 18.0 14.1 12.7 12.5 12.9 15.4 16.2 15.1 13.6 14.9 17.2 11.6 28.9 39.5 64.9 21.2 7.0 13.5 11.9 13.1 23.7 18.0 17.5 53.8 15.7 19.3 1.8 16.7 13.2 25.8 12.3 7.9 12.6 37.5 24.8 18.1 13.7 8.4 35.3 43.2 14.3 12.7 20.4 10.7 23.7 17.1 41.4 8.6 22.2 10.8 18.5 38.4 12.1 18.3 9.4 8.6 30.6 22.1 25.8 12.4 26.2 13.2 20.4 24.7 66.9 148.7 11.8 8.1 23.3 27.7 9.5 5.6 4.6 35.0 28.9 32.9 43.6 22.3 58.4 36.4 17.8 6.8 7.3 23.1 23.0 11.6 7.7 CDKN2C "INK4C, p18" ENSG00000123080 "Cyclin dependent kinase inhibitor 2C" P42773 1 50960745-50974634 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 98.4;lymphoid tissue: 96.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 73.5;Sertoli cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 273.1;U-937: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005303, CAB018398, HPA019057, HPA019764" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB005303: AB_2078729, CAB018398: AB_2078731, HPA019057: AB_1854865, HPA019764: AB_1854866" "unprognostic (4.07e-2)" "unprognostic (1.47e-3)" "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "unprognostic (6.70e-2)" "unprognostic (4.76e-3)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.70e-10)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.24e-1)" 98.4 23.2 21.6 9.1 23.6 36.0 30.6 22.6 31.4 17.5 20.3 19.3 13.4 20.4 11.8 11.1 15.2 15.5 24.2 21.6 23.0 10.4 7.2 9.9 22.5 23.0 22.4 47.6 17.4 19.9 7.8 7.3 24.0 9.9 12.6 7.8 8.8 24.9 20.5 18.9 14.2 22.2 21.2 11.1 7.4 5.2 22.2 96.2 9.7 8.6 23.4 13.1 16.3 30.3 67.6 32.9 5.9 99.6 108.0 16.4 1.5 61.8 76.2 121.8 107.8 1.8 25.7 140.3 58.5 63.5 41.6 8.2 71.4 9.8 63.4 78.4 90.7 102.5 254.6 21.5 5.5 74.0 42.8 5.6 1.9 32.8 14.6 45.6 32.7 115.0 45.0 0.0 76.2 22.0 91.1 40.4 0.1 31.6 71.3 108.6 86.8 0.4 42.9 34.1 49.6 114.3 88.1 67.5 23.6 0.6 31.3 273.1 21.6 130.8 44.1 76.3 0.9 128.1 131.9 113.2 0.0 284.5 118.3 22.4 3.7 17.9 7.3 2.2 8.4 4.9 10.8 9.7 9.3 4.3 6.0 5.8 0.4 10.5 0.9 11.5 22.0 5.6 21.6 23.6 22.6 31.4 21.6 23.0 23.0 22.4 24.0 21.2 22.2 30.3 9.5 0.0 3.9 2.0 5.6 10.1 2.6 8.1 23.9 8.2 3.8 29.5 14.3 5.7 6.1 3.7 16.7 4.9 11.3 2.8 17.6 6.3 4.9 1.1 18.2 8.1 8.4 73.5 0.6 3.4 12.1 31.0 3.1 1.2 16.5 12.6 20.3 8.8 28.3 5.0 0.6 10.2 14.2 20.5 16.0 7.1 39.4 11.0 7.2 1.9 17.1 26.9 17.5 2.0 3.3 3.1 10.2 47.8 14.0 1.8 24.6 40.8 3.2 9.9 85.5 38.9 26.7 32.0 15.0 22.0 11.2 1.9 18.2 28.6 9.1 1.2 CDT1 "DUP, RIS2" ENSG00000167513 "Chromatin licensing and DNA replication factor 1" Q9H211 16 88803789-88809258 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 38.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.4;Erythroid cells: 71.3;Extravillous trophoblasts: 92.0;Spermatogonia: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 149.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017224 Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA017224: AB_1846468" "unprognostic (1.33e-1)" "unprognostic (2.04e-2)" "unprognostic (7.32e-2)" "unprognostic (2.67e-1)" "unprognostic (4.34e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (3.44e-3)" "unprognostic (2.81e-2)" "unprognostic (4.59e-2)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.69e-6)" "unprognostic (7.72e-3)" "unprognostic (5.79e-2)" "unprognostic (2.80e-2)" "unprognostic (8.54e-2)" 0.7 0.8 0.8 3.8 1.2 38.5 0.7 2.5 1.3 1.7 0.0 3.3 4.1 0.5 0.2 6.7 0.5 0.2 0.5 0.8 2.3 0.7 1.0 1.3 4.8 2.2 1.1 0.4 0.6 1.3 2.1 2.8 1.9 0.7 1.6 0.4 1.1 0.2 0.1 3.6 3.9 0.6 0.7 3.1 2.4 3.5 1.1 8.7 0.6 0.0 3.3 0.5 2.3 1.0 33.6 34.5 16.5 25.3 0.7 3.4 64.2 24.1 6.6 19.4 12.0 79.3 33.8 51.4 24.2 5.5 12.7 46.0 21.6 17.7 6.2 18.2 92.1 51.8 28.8 59.9 0.3 28.8 21.5 1.8 1.4 19.8 4.4 1.6 5.9 60.9 80.8 18.4 7.6 90.6 109.3 149.4 41.8 12.2 31.6 120.3 22.9 42.4 4.3 23.8 36.6 26.2 44.4 13.1 16.9 7.4 39.0 55.9 5.9 24.6 42.6 37.2 35.4 61.4 55.7 73.6 19.3 71.9 31.6 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.7 0.4 0.1 0.1 0.7 0.2 0.8 1.2 2.5 1.3 0.8 2.3 2.2 1.1 1.9 0.7 1.1 1.0 0.4 0.0 1.1 0.7 4.9 11.2 4.3 1.4 7.4 0.7 5.4 7.5 2.2 1.5 1.7 1.8 0.0 51.4 2.2 12.7 1.9 1.1 0.4 1.4 1.4 2.2 2.4 71.3 0.2 0.0 92.0 5.2 9.2 2.2 0.0 29.0 0.4 1.0 19.5 0.0 0.8 16.1 4.1 5.6 5.5 1.2 0.3 2.8 1.8 0.0 1.9 1.5 4.1 0.0 0.6 0.6 2.3 0.4 23.1 2.2 2.0 1.6 2.1 1.9 0.0 2.1 3.4 6.6 37.1 10.8 7.1 24.8 5.4 5.7 30.1 4.4 CENPA "CenH3, CENP-A" ENSG00000115163 "Centromere protein A" P49450 2 26764289-26801067 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.0;Extravillous trophoblasts: 33.2;Granulosa cells: 24.2;Plasma cells: 17.8;Spermatogonia: 28.6" "Cancer enhanced" "Detected in many" "testis cancer: 24.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB008371, HPA073086" Enhanced Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008371: AB_591074, HPA073086: AB_2686569" "unprognostic (3.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.13e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (2.88e-8)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.69e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.21e-3)" "unprognostic (0.00e+0)" "unprognostic (5.74e-2)" "unprognostic (1.33e-1)" "unprognostic (7.68e-2)" "unprognostic (2.07e-1)" 0.2 0.3 0.0 4.0 0.0 3.7 0.4 0.1 0.1 0.5 0.0 2.9 4.1 0.7 0.0 3.7 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.4 7.3 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.1 2.6 0.0 0.6 0.0 0.0 3.6 2.9 0.9 0.0 2.0 1.6 2.2 0.1 13.3 0.1 0.0 8.4 0.7 1.1 0.0 86.4 21.0 34.9 19.3 2.4 4.5 24.3 26.2 22.2 37.3 31.5 15.4 30.0 25.7 16.2 10.4 45.7 25.6 28.9 15.3 37.7 77.3 25.6 44.0 11.0 28.6 0.8 26.7 49.0 0.4 1.6 16.1 24.4 6.7 22.1 33.7 36.7 58.5 32.5 30.1 39.0 42.2 26.6 35.3 34.3 45.4 53.6 30.8 17.5 5.5 27.5 26.7 25.7 32.7 23.6 12.9 18.2 27.2 12.6 23.9 54.2 27.9 46.4 51.5 53.5 107.3 11.1 54.7 46.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.2 6.2 0.7 1.9 1.8 0.0 2.0 2.5 2.7 0.0 0.5 0.0 0.0 15.3 1.0 2.3 0.0 0.5 0.6 1.6 1.6 1.5 4.2 45.0 0.1 0.2 33.2 4.9 2.6 3.0 0.0 24.2 3.9 0.6 15.7 0.0 0.1 6.6 0.0 2.9 2.8 0.1 0.9 4.4 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 1.4 0.0 17.8 2.1 0.8 0.2 0.1 0.0 0.0 0.6 3.9 16.1 28.6 12.5 5.3 3.4 3.4 1.5 11.1 2.0 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.8;testis: 29.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 74.5;Spermatocytes: 222.7;Spermatogonia: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: AB_10673354" "unprognostic (1.49e-1)" "prognostic favorable (6.86e-4)" "unprognostic (1.73e-2)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.22e-5)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "prognostic favorable (2.50e-4)" "unprognostic (4.21e-2)" "unprognostic (8.80e-2)" "prognostic unfavorable (5.11e-15)" "unprognostic (1.17e-1)" "unprognostic (3.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" 4.2 2.0 1.4 7.5 1.7 33.8 7.7 1.7 2.0 3.9 1.0 7.4 6.5 4.5 2.1 7.5 4.0 1.8 4.0 1.5 1.6 1.6 3.6 2.8 17.7 1.6 1.5 3.9 1.5 2.0 1.4 5.2 1.6 3.3 8.1 2.5 2.9 2.3 4.0 9.2 5.9 3.7 1.4 5.2 3.7 29.7 1.6 18.5 2.5 4.0 18.8 3.8 4.4 2.2 64.6 19.4 88.6 70.2 5.8 18.3 48.0 31.2 32.6 66.9 71.8 26.5 79.6 138.9 36.6 18.1 39.1 47.0 59.0 70.4 85.1 42.7 41.4 32.7 32.5 26.4 2.0 47.1 32.1 7.1 14.6 43.6 47.7 18.9 23.2 73.7 58.7 53.3 52.2 35.6 152.4 67.3 78.1 20.7 17.0 93.2 118.2 108.2 21.1 22.9 61.6 81.9 34.6 22.8 27.5 47.7 31.9 31.4 11.4 33.4 56.1 44.5 78.7 65.5 106.3 111.8 51.1 94.2 64.7 1.0 2.0 3.0 4.7 3.5 7.7 13.3 7.9 6.0 3.1 14.1 9.9 8.6 0.4 8.6 4.2 6.7 9.7 4.8 1.4 1.7 1.7 2.0 1.5 1.6 1.6 1.5 1.6 1.4 1.6 2.2 4.8 0.0 2.6 1.0 18.3 36.7 17.7 17.4 9.6 3.4 10.8 11.7 3.3 4.3 7.1 0.0 0.0 37.4 9.2 5.1 0.0 12.3 26.5 5.5 5.1 6.9 1.2 74.5 1.3 9.1 49.0 7.4 2.6 4.8 5.1 22.4 4.6 1.1 17.0 0.0 1.1 9.5 12.2 7.5 18.2 22.5 3.7 6.3 8.8 1.0 4.3 7.3 6.2 1.0 0.9 7.0 2.5 4.9 14.4 6.9 1.4 3.4 10.8 3.5 19.7 6.4 9.3 222.7 222.8 12.1 19.2 10.0 12.0 6.9 15.9 15.2 CENPI "CENP-I, FSHPRH1, LRPR1, Mis6" ENSG00000102384 "Centromere protein I" Q92674 X 101098218-101163681 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.8;lymphoid tissue: 7.1" "Cell type enhanced" "Detected in some" "Erythroid cells: 4.8;Excitatory neurons: 2.9;Extravillous trophoblasts: 4.7;Granulosa cells: 3.2;Oligodendrocytes: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061297 Supported "Nuclear bodies,Cytosol" NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" Cytosol "HPA061297: AB_2684471" "unprognostic (3.10e-3)" "unprognostic (9.71e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (5.78e-6)" "unprognostic (2.96e-2)" "unprognostic (7.71e-3)" "unprognostic (3.62e-3)" "unprognostic (1.20e-3)" "unprognostic (4.51e-2)" "unprognostic (2.50e-13)" "unprognostic (1.25e-2)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.42e-1)" 1.1 0.6 0.9 3.1 1.0 6.8 1.2 2.0 1.0 1.0 0.5 2.7 2.8 1.8 1.4 2.6 0.6 1.4 0.5 1.1 1.1 0.4 0.8 1.0 5.4 1.4 0.6 2.3 0.9 0.2 0.0 2.5 1.4 1.2 3.5 1.8 0.5 0.6 0.2 3.2 2.3 2.7 0.1 1.6 1.5 1.2 1.0 7.1 0.8 0.6 6.3 1.4 0.8 2.9 44.9 30.3 36.6 28.1 4.6 8.2 16.4 47.5 25.2 47.1 94.5 40.9 28.0 32.7 16.5 18.8 72.5 25.7 54.2 25.3 65.4 20.6 13.8 20.2 43.5 15.6 0.5 26.8 21.2 3.3 2.2 62.5 7.7 13.5 40.7 23.3 14.5 58.3 46.1 31.5 26.7 9.8 28.3 21.2 36.8 24.7 53.0 21.0 11.8 26.4 23.4 12.3 58.1 16.3 9.6 33.0 16.2 8.6 16.7 44.0 36.6 41.2 38.3 9.1 23.3 36.5 17.3 35.2 34.7 0.7 0.5 0.6 0.4 0.7 0.3 0.6 0.4 0.6 0.2 0.4 0.4 0.4 1.1 0.7 0.7 0.7 0.8 0.3 0.9 1.0 2.0 1.0 1.1 1.1 1.4 0.6 1.4 0.1 1.0 2.9 0.5 0.0 0.0 2.3 0.9 0.3 0.1 0.6 0.0 0.5 0.4 0.3 0.4 0.0 0.7 0.0 0.0 1.9 0.5 0.8 0.0 0.2 0.2 0.4 0.8 0.5 0.0 4.8 2.9 0.0 4.7 0.6 0.0 0.6 0.0 3.2 0.7 0.2 1.4 0.0 2.3 0.7 0.0 0.6 0.8 0.0 0.3 0.3 0.0 1.0 0.6 0.5 0.0 1.5 3.3 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.1 0.3 0.0 0.7 1.0 0.3 0.9 1.4 0.1 0.3 0.4 0.8 1.4 0.2 CENPK "CENP-K, FKSG14, SOLT" ENSG00000123219 "Centromere protein K" Q9BS16 5 65517766-65563168 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.6;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.9;Extravillous trophoblasts: 50.6;Spermatocytes: 101.3;Spermatogonia: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (4.04e-2)" "unprognostic (1.77e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-3)" "unprognostic (3.69e-4)" "unprognostic (3.22e-3)" "unprognostic (9.59e-3)" "unprognostic (3.32e-2)" "unprognostic (3.16e-3)" "unprognostic (1.98e-2)" "unprognostic (6.33e-15)" "unprognostic (2.22e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-2)" "unprognostic (3.11e-1)" 1.1 0.9 0.6 10.6 0.7 24.6 3.8 1.0 0.8 1.2 1.6 9.0 8.3 1.9 0.9 5.6 2.3 1.9 0.5 0.5 0.6 0.8 1.9 2.0 14.6 1.0 0.7 0.8 0.6 1.0 0.3 5.5 1.1 1.3 11.9 0.7 1.4 0.7 0.2 8.6 8.6 3.4 0.7 4.5 5.5 13.4 1.0 22.2 1.2 0.5 12.4 2.6 2.4 1.4 65.3 41.4 85.6 29.5 4.4 12.0 40.8 69.8 26.5 58.7 73.6 35.1 97.2 39.3 25.2 23.6 59.5 39.7 33.3 35.4 92.7 45.2 28.5 42.1 50.7 33.8 1.7 50.1 36.8 5.6 5.0 56.9 27.3 10.6 56.4 42.2 31.8 57.7 59.1 21.5 85.4 56.2 41.1 18.5 17.1 52.5 81.9 43.8 38.8 34.4 35.8 28.9 53.7 22.1 28.7 31.8 40.0 36.9 20.3 44.9 46.5 31.1 82.2 30.0 51.9 83.0 41.9 74.0 49.9 3.7 0.7 2.3 9.9 1.0 14.8 4.0 21.1 12.5 1.7 7.0 28.5 20.2 1.7 10.2 1.1 1.6 23.2 10.0 0.6 0.7 1.0 0.8 0.5 0.6 1.0 0.7 1.1 0.7 1.0 1.4 2.7 0.0 3.4 0.3 11.7 23.6 8.5 14.0 4.6 1.6 6.0 7.9 0.9 0.0 8.1 0.0 0.0 28.8 18.7 5.8 1.9 3.1 27.6 25.5 4.5 5.7 0.0 50.9 3.1 1.0 50.6 6.3 9.2 7.2 2.5 22.7 3.9 1.1 22.4 0.0 2.3 14.7 8.2 1.9 12.0 17.4 1.5 5.7 1.8 11.2 1.8 0.6 7.2 2.0 1.4 2.3 2.1 1.5 14.1 2.2 1.1 0.3 7.1 1.1 0.0 2.3 9.1 101.3 75.1 17.0 8.1 6.7 20.7 3.9 15.8 11.4 CENPL "C1orf155, dJ383J4.3, FLJ31044" ENSG00000120334 "Centromere protein L" Q8N0S6 1 173799550-173824720 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.6;testis: 9.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044520 Uncertain NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA044520: AB_10794500" "unprognostic (8.72e-3)" "unprognostic (2.82e-2)" "unprognostic (3.39e-1)" "unprognostic (1.34e-3)" "unprognostic (7.89e-2)" "unprognostic (7.88e-3)" "unprognostic (6.43e-6)" "unprognostic (8.18e-2)" "prognostic unfavorable (2.51e-4)" "prognostic favorable (3.60e-4)" "unprognostic (1.78e-3)" "unprognostic (5.00e-2)" "unprognostic (1.46e-10)" "unprognostic (2.16e-2)" "unprognostic (4.41e-2)" "unprognostic (3.10e-2)" "unprognostic (3.09e-1)" 2.1 1.2 1.4 3.1 1.5 9.6 2.4 1.4 1.8 1.9 1.0 2.4 2.3 1.8 1.0 2.3 1.2 1.7 1.7 1.2 1.3 1.4 1.0 1.3 6.6 1.7 1.3 1.6 0.7 1.1 0.6 3.0 1.6 1.3 3.0 1.5 1.4 1.2 1.4 2.2 1.8 2.4 1.6 2.1 2.1 9.8 1.3 9.1 1.7 2.7 5.7 1.9 1.4 1.8 27.5 7.3 13.5 18.2 3.9 6.7 9.9 23.6 14.4 24.9 17.3 9.5 14.3 19.8 11.0 12.9 9.4 17.6 14.6 11.6 27.4 18.0 7.2 14.6 7.6 5.5 1.9 22.4 14.7 3.4 3.9 17.6 14.0 4.7 14.8 15.2 25.8 28.6 23.0 6.4 18.5 10.3 14.1 19.3 40.4 18.9 16.7 16.7 8.9 7.5 13.6 11.3 18.7 22.5 15.7 10.9 15.8 18.5 8.6 28.6 19.6 14.8 27.6 15.9 29.2 31.5 9.4 16.4 26.6 3.9 1.0 2.4 4.7 1.1 5.3 3.3 4.3 5.5 0.9 5.0 5.5 6.0 0.6 8.6 0.7 4.3 7.1 2.6 1.4 1.5 1.4 1.8 1.2 1.3 1.7 1.3 1.6 1.6 1.3 1.8 16.0 9.6 3.7 1.6 8.5 4.7 6.9 2.8 1.2 4.9 7.3 24.5 5.0 2.8 2.1 1.8 14.6 9.2 13.1 4.8 0.0 2.2 2.2 4.6 12.8 6.3 1.8 22.7 2.2 3.8 15.9 7.7 3.1 7.9 4.5 13.1 3.3 0.8 6.7 1.7 2.0 4.8 2.0 4.4 7.1 3.3 4.7 4.5 5.4 2.8 3.6 2.4 7.2 1.5 2.5 3.6 4.5 1.9 7.4 6.3 4.0 1.3 1.7 4.7 0.0 14.5 10.7 38.8 20.2 8.8 6.0 5.9 9.2 11.2 5.3 4.5 CENPM "C22orf18, CENP-M, MGC861, Pane1" ENSG00000100162 "Centromere protein M" Q9NSP4 22 41938737-41947152 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.0;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 116.7;Erythroid cells: 60.0;Plasma cells: 70.8;Respiratory ciliated cells: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 50.8" "Group enriched" "Detected in many" 6 "B-cells: 38.6;T-cells: 50.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042404 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "HPA042404: AB_2677981" "unprognostic (3.78e-2)" "prognostic favorable (3.40e-5)" "unprognostic (7.15e-3)" "unprognostic (2.65e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (5.50e-5)" "unprognostic (1.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (5.99e-7)" "unprognostic (9.54e-3)" "unprognostic (2.44e-1)" "unprognostic (8.73e-2)" "unprognostic (5.61e-2)" 1.3 1.5 0.6 9.9 0.6 29.0 1.9 1.8 1.1 2.3 0.3 9.9 8.4 1.7 0.1 9.9 10.8 2.0 0.7 0.5 0.7 2.3 1.6 3.8 25.1 0.8 0.8 0.7 0.7 0.3 0.5 3.2 0.8 1.4 5.3 0.1 3.6 0.3 0.9 8.0 8.3 1.8 0.5 10.6 6.1 12.8 1.0 22.6 0.8 0.4 16.3 2.0 4.0 0.5 79.1 79.0 43.5 28.8 3.3 3.3 18.4 37.8 19.4 65.2 66.2 92.3 41.0 101.5 27.8 20.2 42.2 29.5 32.9 38.8 16.2 29.4 137.4 47.8 82.3 64.9 3.2 91.4 51.9 2.7 2.9 42.1 19.3 6.9 24.8 91.5 36.7 95.0 38.8 121.9 91.9 94.8 23.6 47.5 58.1 86.8 43.4 105.6 26.9 46.5 49.3 9.4 58.5 34.5 20.6 7.2 32.8 58.4 12.5 62.8 93.4 42.0 64.1 50.5 38.0 95.2 21.9 75.9 70.0 1.8 0.3 0.0 6.2 0.2 8.8 27.9 18.6 8.4 0.7 38.6 3.5 4.6 1.1 7.4 0.2 0.4 50.8 7.9 0.6 0.6 1.8 1.1 0.5 0.7 0.8 0.8 0.8 0.5 1.0 0.5 0.4 0.0 3.4 0.3 50.7 2.0 4.8 17.8 1.8 1.9 10.9 10.3 0.6 0.0 7.9 0.0 0.0 39.7 5.4 25.3 17.6 2.1 4.5 116.7 4.2 2.6 7.7 60.0 0.5 0.7 38.9 6.4 10.7 18.0 2.5 15.8 3.6 1.3 43.4 3.3 0.8 34.5 28.5 2.9 3.5 6.7 1.2 5.4 7.2 1.0 1.8 0.1 2.1 1.0 0.2 1.5 8.4 0.4 70.8 2.8 4.0 0.3 102.6 0.6 0.0 0.2 7.0 36.4 29.8 13.3 1.0 8.8 18.5 2.9 36.6 9.0 CENPN "BM039, C16orf60, FLJ13607, FLJ22660" ENSG00000166451 "Centromere protein N" Q96H22 16 81006552-81033114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 64.2;Extravillous trophoblasts: 91.1;Spermatocytes: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052870 Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA052870: AB_2681978" "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.15e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.76e-2)" "unprognostic (3.69e-3)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.02e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-2)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (7.99e-2)" 5.1 5.0 3.2 7.9 4.0 37.4 3.6 3.1 4.9 2.8 2.1 8.0 7.8 2.3 3.1 7.5 1.6 3.1 5.7 3.3 3.1 5.4 9.0 3.3 11.0 3.8 4.0 1.5 5.2 8.6 1.6 8.9 3.4 18.7 7.6 1.4 2.5 2.7 4.5 3.8 6.4 6.4 2.7 4.3 5.2 11.2 3.9 18.1 2.8 2.6 12.0 6.0 2.8 5.8 86.2 81.0 64.9 58.4 16.9 15.1 82.6 97.5 59.3 137.0 59.6 150.8 64.6 48.1 52.4 48.9 62.7 69.9 53.1 61.5 172.9 29.3 47.9 43.0 63.3 100.9 9.6 64.6 80.4 14.0 6.6 123.3 40.8 18.0 62.6 59.1 83.6 65.9 66.9 160.1 78.0 79.6 69.7 37.2 45.4 90.9 64.5 51.3 22.5 58.6 43.2 38.9 140.3 31.8 40.1 38.9 76.2 34.0 38.5 97.7 101.1 66.8 96.8 46.4 112.1 186.8 45.8 43.7 85.8 0.9 1.4 2.4 2.1 2.8 2.0 1.6 2.7 1.5 6.6 5.9 1.3 1.5 1.7 3.6 3.1 2.2 7.9 2.0 3.2 4.0 3.1 4.9 3.3 3.1 3.8 4.0 3.4 2.7 3.9 5.8 2.8 0.0 4.8 1.0 10.2 24.0 15.7 9.6 14.8 1.0 6.0 7.0 4.8 5.7 5.8 3.7 0.0 47.1 10.0 7.4 0.0 5.7 41.8 4.5 3.8 5.8 1.2 64.2 1.9 6.5 91.1 9.7 11.7 6.4 6.3 13.2 6.8 6.3 27.2 0.0 1.1 12.8 12.2 9.7 20.2 40.9 2.8 10.4 7.2 1.0 4.4 0.8 0.0 0.5 6.1 5.1 4.0 3.4 34.7 13.6 5.1 8.8 1.8 0.4 0.0 7.1 10.0 52.3 39.1 32.7 16.3 27.2 10.9 6.3 22.0 16.6 CENPO "CENP-O, MGC11266" ENSG00000138092 "Centromere protein O" Q9BU64 2 24793136-24822376 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 11.2;Extravillous trophoblasts: 11.5;Spermatocytes: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046189 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA046189: AB_2679579" "unprognostic (1.67e-2)" "unprognostic (2.42e-1)" "unprognostic (1.98e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.79e-1)" "unprognostic (7.48e-3)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.56e-2)" "unprognostic (4.02e-1)" "unprognostic (4.81e-2)" "unprognostic (5.93e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (5.71e-13)" "unprognostic (4.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" 5.2 4.0 3.5 3.5 3.3 9.2 4.6 2.9 4.1 4.0 2.3 3.3 3.2 3.1 0.8 4.5 3.0 1.5 2.8 3.7 3.5 2.9 2.6 3.6 4.9 3.7 3.4 4.5 1.9 1.6 3.6 3.2 3.5 3.1 3.7 1.4 2.5 1.1 3.0 3.8 3.9 2.2 3.2 4.3 2.7 8.3 3.8 11.4 3.4 2.0 5.8 2.5 3.7 3.1 31.1 36.4 40.7 21.7 4.8 7.3 22.7 36.8 21.7 51.0 38.7 46.2 15.5 21.4 4.2 22.8 29.8 16.3 40.6 14.0 34.1 28.1 21.1 34.3 23.9 31.0 2.4 28.7 24.4 3.6 2.5 51.5 11.4 9.3 24.0 25.4 40.3 23.8 31.8 21.8 39.2 20.6 29.3 21.0 22.8 31.0 53.4 11.5 12.9 18.6 27.0 29.3 22.1 16.9 7.9 18.5 16.3 11.8 15.4 46.9 42.8 15.9 41.6 14.5 20.1 42.8 14.5 27.5 36.4 0.0 0.3 0.0 1.0 0.2 0.4 0.4 0.4 0.5 0.4 0.3 0.3 0.7 0.1 0.7 0.3 1.1 0.7 0.3 3.5 3.3 2.9 4.1 3.7 3.5 3.7 3.4 3.5 3.2 3.8 3.1 0.7 3.2 2.2 4.2 1.5 1.1 0.7 1.3 2.2 0.9 1.9 1.4 6.5 0.0 1.2 3.7 0.0 3.9 1.9 3.0 1.9 1.5 3.9 1.5 2.2 2.0 0.0 11.2 5.3 1.3 11.5 2.4 6.6 1.5 1.3 6.5 1.8 0.9 4.9 1.7 4.9 1.6 0.0 1.6 1.1 9.6 0.3 1.1 1.8 3.7 1.2 1.6 1.0 2.0 2.5 1.1 0.5 1.2 8.6 0.5 1.8 1.7 0.7 0.7 0.0 1.1 3.3 11.7 9.5 3.3 1.4 2.9 1.4 2.8 2.7 0.9 CENPQ "C6orf139, CENP-Q, FLJ10545" ENSG00000031691 "Centromere protein Q" Q7L2Z9 6 49463370-49493107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029043, HPA046634, HPA054965" Approved Supported Nucleoplasm NA Yes "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA029043: AB_2672881, HPA046634: AB_2679728, HPA054965: AB_2682653" "unprognostic (7.39e-2)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.49e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.21e-5)" "unprognostic (1.36e-1)" "unprognostic (1.76e-2)" "prognostic favorable (6.26e-4)" "unprognostic (2.89e-1)" "unprognostic (8.19e-2)" "unprognostic (1.48e-3)" "unprognostic (8.93e-2)" "unprognostic (7.47e-2)" "unprognostic (2.74e-3)" "unprognostic (2.56e-1)" 4.8 4.7 4.7 5.4 5.8 4.9 5.4 5.8 6.9 3.1 3.8 3.9 2.8 4.7 3.0 4.3 4.0 3.5 6.4 4.2 5.1 3.8 4.4 3.8 7.0 5.8 5.2 6.2 2.5 3.6 2.3 5.9 6.0 4.5 4.7 4.2 2.8 3.3 5.0 4.0 3.3 4.4 5.3 4.7 3.8 6.0 4.8 9.4 3.7 8.4 8.4 3.7 3.3 7.6 35.3 9.7 30.1 18.9 8.0 12.4 26.4 44.6 25.5 41.9 58.4 11.9 13.8 23.7 21.7 12.7 32.8 12.5 15.8 16.2 61.6 25.9 22.0 17.5 14.6 19.2 3.4 37.4 21.2 5.7 8.7 51.5 17.9 10.7 15.5 20.4 27.3 22.9 31.4 10.2 26.4 17.6 18.8 30.6 8.7 18.8 35.6 25.8 12.3 14.3 16.2 16.0 21.0 12.4 23.9 29.6 15.9 33.8 9.2 32.3 25.2 25.7 40.4 10.4 28.9 21.4 21.9 27.8 32.0 2.2 1.2 4.1 2.0 1.4 2.0 4.4 2.1 2.3 1.3 4.5 2.3 2.3 0.9 2.4 1.8 2.7 3.2 1.2 4.7 5.8 5.8 6.9 4.2 5.1 5.8 5.2 6.0 5.3 4.8 7.6 8.6 0.0 2.7 7.2 9.5 8.7 9.9 10.4 8.6 6.3 4.1 4.7 6.2 4.3 5.2 7.3 2.1 17.3 8.7 4.2 7.9 7.8 1.3 8.8 5.6 8.0 2.4 5.9 3.0 7.9 30.8 9.3 6.6 5.4 4.5 6.3 14.3 3.4 10.1 6.7 3.1 3.7 2.0 11.4 6.0 2.3 8.7 5.9 3.6 11.2 7.6 14.5 13.4 6.6 13.5 7.8 8.0 10.9 7.5 5.4 1.7 4.4 9.4 5.1 6.6 15.2 6.5 17.7 34.6 6.5 7.0 12.4 5.9 4.2 5.9 6.2 CENPW "C6orf173, CUG2" ENSG00000203760 "Centromere protein W" Q5EE01 6 126340115-126348875 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.6;testis: 39.5" "Cell type enhanced" "Detected in many" "Early spermatids: 329.7;Extravillous trophoblasts: 155.9;Spermatocytes: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA067285 Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067285: AB_2685818" "unprognostic (3.51e-3)" "unprognostic (2.35e-1)" "unprognostic (3.26e-3)" "unprognostic (9.61e-3)" "unprognostic (3.78e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.21e-5)" "unprognostic (1.11e-2)" "unprognostic (2.82e-2)" "unprognostic (9.07e-2)" "unprognostic (5.86e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.07e-1)" "unprognostic (1.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.22e-1)" 8.2 4.3 2.5 12.8 2.3 50.6 6.6 2.0 3.5 14.4 1.4 15.0 8.3 21.6 7.0 23.1 9.2 5.4 1.7 4.2 2.0 3.4 3.6 4.9 15.5 1.9 2.0 4.1 2.1 2.8 2.5 7.8 1.7 6.3 17.5 1.6 8.5 4.4 3.0 8.3 10.8 16.1 1.9 6.8 6.3 39.5 2.0 27.4 2.5 1.9 20.5 6.6 10.9 2.4 73.4 49.0 94.7 82.9 10.3 10.4 81.2 60.0 43.6 81.3 98.3 148.0 50.1 86.8 48.8 38.3 128.7 88.0 78.0 94.3 114.6 94.0 140.2 84.7 141.4 166.3 3.4 123.8 59.1 6.4 10.0 69.1 51.2 23.1 88.3 116.8 144.1 56.5 69.6 119.3 103.1 204.4 60.5 64.0 74.3 107.7 63.2 62.6 38.0 33.0 99.1 44.0 50.8 46.5 67.4 76.9 43.7 119.5 48.0 76.6 78.3 104.6 163.7 36.9 72.7 156.8 45.9 147.0 92.8 3.2 16.9 2.3 2.0 20.3 0.6 6.0 4.4 4.3 15.9 3.5 3.4 2.7 2.9 6.9 14.1 18.9 12.0 5.9 2.5 2.3 2.0 3.5 4.2 2.0 1.9 2.0 1.7 1.9 2.0 2.4 2.5 0.0 2.6 1.0 18.6 38.0 13.4 54.3 6.2 1.3 10.3 18.7 0.3 11.5 29.4 1.8 2.1 52.2 6.1 23.5 5.9 16.6 329.7 18.0 26.5 11.0 7.8 75.1 23.7 17.9 155.9 25.1 17.3 12.7 13.4 31.4 10.8 6.0 63.6 3.3 22.0 27.1 42.7 15.6 40.1 39.3 19.3 19.3 8.8 1.0 12.6 3.1 3.1 1.0 2.4 17.2 10.6 9.1 38.6 24.7 18.1 1.6 7.0 1.4 0.0 6.4 18.1 148.3 83.8 60.9 29.0 21.2 8.6 11.4 51.7 35.8 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CEP97 "FLJ23047, LRRIQ2" ENSG00000182504 "Centrosomal protein 97" Q8IW35 3 101724593-101770562 "Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002980 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 12: Non-specific - Cell cycle regulation" "HPA002980: AB_1848820" "unprognostic (7.36e-2)" "unprognostic (4.70e-2)" "unprognostic (1.20e-1)" "unprognostic (1.03e-1)" "unprognostic (1.08e-1)" "unprognostic (3.33e-2)" "unprognostic (2.01e-3)" "unprognostic (1.00e-1)" "unprognostic (2.85e-1)" "unprognostic (4.04e-1)" "unprognostic (5.68e-2)" "unprognostic (1.34e-1)" "unprognostic (1.12e-3)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.79e-1)" "unprognostic (1.05e-1)" 2.1 2.7 4.6 3.6 7.7 4.9 2.6 6.0 6.4 2.3 3.1 2.1 1.7 3.5 2.5 2.0 5.3 2.2 2.0 4.5 5.8 2.2 1.3 2.3 4.6 6.1 6.4 3.2 1.1 6.1 2.7 2.7 5.9 2.4 2.3 5.5 2.0 2.2 2.6 2.7 1.8 4.2 5.7 3.0 2.3 7.3 5.6 5.9 3.3 3.5 4.5 2.4 2.0 12.7 12.0 7.0 11.7 8.7 6.5 5.2 3.6 12.6 8.8 9.6 11.8 3.0 5.5 10.6 5.6 7.1 7.7 7.9 8.8 6.9 16.1 11.5 4.3 6.0 7.6 2.2 3.2 7.6 8.9 3.0 5.6 8.2 6.9 5.1 5.4 10.4 4.9 17.9 11.8 3.6 12.4 4.0 4.2 4.3 9.1 9.0 16.1 7.2 3.3 4.5 22.4 9.2 6.8 4.5 6.1 6.1 7.4 6.8 5.4 12.9 9.5 3.8 9.4 11.3 11.0 18.3 5.3 6.8 13.0 2.1 0.1 0.6 0.7 0.0 0.5 1.0 0.6 0.4 0.1 0.5 0.4 0.3 0.9 0.3 0.4 0.4 0.8 0.2 4.6 7.7 6.0 6.4 4.5 5.8 6.1 6.4 5.9 5.7 5.6 12.7 8.7 3.2 6.2 24.5 9.1 4.7 2.4 4.7 9.1 13.6 5.2 4.3 7.0 4.3 9.6 1.8 12.5 3.7 14.6 1.6 3.9 4.4 20.7 32.7 14.3 6.4 4.2 9.1 28.6 2.1 2.9 8.8 5.1 10.4 9.5 14.5 3.9 4.1 2.8 18.5 36.0 3.7 10.2 3.1 2.7 9.1 7.8 3.0 8.8 8.4 3.4 19.6 4.1 50.8 96.5 4.0 1.0 7.5 24.0 1.8 0.9 3.1 42.5 14.6 13.1 13.1 8.6 30.4 11.9 8.0 3.7 1.9 9.2 11.0 3.3 1.5 CHAC2 GCG1 ENSG00000143942 "ChaC glutathione specific gamma-glutamylcyclotransferase 2" Q8WUX2 2 53767804-53775196 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 44.0;Plasma cells: 27.0;Spermatocytes: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049235 Approved Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA049235: AB_2680686" "unprognostic (2.22e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (3.91e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "prognostic unfavorable (3.80e-7)" "unprognostic (5.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.30e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (4.28e-6)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" 5.0 4.4 1.6 4.8 1.7 6.9 2.1 2.4 2.4 1.2 0.9 4.4 7.3 1.1 2.6 4.5 0.7 1.3 2.5 1.6 2.0 2.9 4.4 1.4 6.6 1.6 1.6 0.6 1.9 1.3 1.6 1.1 1.5 1.7 3.7 3.7 1.7 1.5 4.9 1.2 4.5 2.2 1.3 4.2 4.5 5.4 1.8 4.9 1.0 4.7 6.5 3.2 2.2 1.4 39.9 13.0 13.5 12.1 6.7 3.3 2.9 17.9 3.6 12.5 14.8 9.1 10.0 33.5 25.3 7.8 18.8 14.0 31.1 21.3 21.7 71.3 27.1 26.6 16.3 15.0 10.2 31.8 11.6 4.2 6.2 23.2 17.5 3.3 24.8 23.0 27.8 19.2 16.6 13.0 38.0 26.5 17.5 17.1 23.1 28.6 28.9 34.2 17.3 10.6 16.8 4.7 20.7 15.3 8.7 8.1 9.3 12.5 11.0 7.3 26.1 28.2 29.3 18.9 26.1 28.8 9.9 39.5 10.2 1.3 0.3 0.8 3.5 0.7 3.7 4.3 3.8 3.9 0.8 4.4 4.3 4.1 1.0 1.1 0.5 1.8 3.9 1.9 1.6 1.7 2.4 2.4 1.6 2.0 1.6 1.6 1.5 1.3 1.8 1.4 2.3 0.0 1.1 2.0 11.7 3.4 3.7 7.4 0.6 1.6 2.2 2.0 3.0 7.2 4.1 1.8 0.0 1.9 5.1 3.4 11.7 5.4 13.1 2.2 1.0 3.0 0.0 44.0 4.8 8.0 0.9 1.6 10.2 2.2 1.3 1.5 3.3 7.6 7.8 1.7 4.3 4.6 2.0 1.9 3.0 3.5 2.8 1.7 3.6 1.0 5.8 5.7 8.2 5.0 2.1 7.9 1.4 4.1 27.0 4.1 3.7 9.8 1.9 6.8 0.0 2.4 3.1 47.0 6.6 5.5 3.4 0.4 5.3 5.1 10.6 4.0 CHAF1A "CAF-1, CAF1, CAF1B, CAF1P150, MGC71229, P150" ENSG00000167670 "Chromatin assembly factor 1 subunit A" Q13111 19 4402640-4445018 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.3;Spermatocytes: 94.3;Spermatogonia: 103.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Group enriched" "Detected in many" 4 "dendritic cells: 15.7;granulocytes: 4.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB015186 Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015186: AB_628065" "unprognostic (1.91e-1)" "prognostic favorable (8.22e-5)" "unprognostic (2.49e-1)" "unprognostic (4.71e-2)" "unprognostic (2.06e-1)" "unprognostic (1.89e-3)" "unprognostic (5.30e-3)" "unprognostic (8.78e-2)" "unprognostic (2.06e-2)" "unprognostic (2.12e-2)" "unprognostic (2.46e-2)" "unprognostic (1.16e-1)" "unprognostic (8.54e-2)" "prognostic favorable (4.15e-6)" "unprognostic (1.71e-1)" "unprognostic (2.11e-3)" "unprognostic (4.03e-2)" 4.9 4.4 3.5 9.7 3.0 31.4 4.8 5.6 6.6 4.7 1.3 6.9 6.5 3.9 2.0 10.2 4.0 2.7 3.9 3.7 3.0 2.4 4.1 4.0 13.4 3.4 3.1 3.7 3.9 3.3 3.7 6.2 3.0 5.8 6.6 3.4 5.5 3.0 12.2 10.8 6.7 4.1 2.4 6.9 5.1 14.5 3.1 16.3 2.9 4.1 10.5 4.7 5.6 4.1 65.8 44.0 71.8 45.3 7.0 8.5 36.7 61.2 24.8 50.5 56.7 53.5 22.8 100.4 24.7 19.6 28.6 50.3 61.6 41.5 59.8 58.1 67.2 62.9 69.4 42.7 3.5 73.7 48.8 4.8 8.6 41.5 17.7 9.4 24.0 54.9 76.8 88.0 31.3 37.8 119.2 40.7 80.1 33.5 35.6 87.2 56.8 57.2 13.1 76.7 50.6 39.2 41.6 29.1 24.5 45.2 25.7 53.9 17.5 41.3 35.9 71.1 74.9 43.7 71.0 96.3 34.7 92.8 49.9 3.8 2.3 4.7 0.5 2.3 0.4 1.6 0.6 0.1 2.1 1.0 0.5 0.4 1.2 1.2 0.4 15.7 0.9 0.9 3.5 3.0 5.6 6.6 3.7 3.0 3.4 3.1 3.0 2.4 3.1 4.1 2.3 0.0 3.9 2.0 12.5 9.7 4.6 3.5 6.2 12.1 5.1 3.6 5.7 1.5 2.6 5.5 2.1 25.3 17.3 13.9 1.9 8.5 6.7 5.3 4.2 4.6 1.8 50.3 4.1 6.7 37.9 6.1 10.7 6.5 2.5 19.3 3.3 4.8 12.1 1.7 3.6 10.7 0.0 4.8 21.4 6.7 3.1 11.8 1.8 1.9 11.5 5.2 5.2 2.5 2.9 6.8 1.7 3.8 32.5 4.1 4.6 1.8 5.0 8.4 32.9 5.7 5.5 94.3 103.8 18.7 14.9 14.6 7.7 9.4 14.6 5.9 CHAF1B "CAF-1, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7" ENSG00000159259 "Chromatin assembly factor 1 subunit B" Q13112 21 36385392-36419015 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 15.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA021679, CAB033604" Enhanced Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB033604: AB_2229411, HPA021679: AB_1846621" "unprognostic (2.28e-2)" "prognostic favorable (5.44e-5)" "prognostic favorable (7.92e-4)" "unprognostic (1.43e-1)" "unprognostic (3.28e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (6.14e-6)" "unprognostic (2.14e-2)" "unprognostic (1.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-2)" "unprognostic (6.27e-2)" "unprognostic (7.66e-6)" "unprognostic (5.89e-2)" "unprognostic (5.00e-3)" "unprognostic (9.12e-2)" "unprognostic (1.36e-1)" 1.3 0.6 1.5 2.4 1.2 6.9 2.6 2.2 1.5 1.3 0.3 1.9 1.6 1.7 1.5 2.5 1.3 0.9 0.6 1.6 0.7 1.3 0.7 1.0 3.0 0.6 0.4 1.4 3.3 1.6 1.0 1.1 0.7 1.6 2.1 1.7 3.0 0.9 15.6 2.7 1.9 1.5 0.1 1.3 1.2 4.2 0.8 4.1 0.9 1.8 3.5 1.0 1.5 1.0 25.5 15.0 25.3 14.4 1.9 5.0 13.8 17.6 10.1 21.4 22.2 17.1 13.3 19.9 7.6 9.2 21.7 8.2 26.3 11.7 17.2 20.2 20.5 30.9 15.5 12.2 1.3 19.8 14.4 3.1 2.8 20.0 8.6 4.1 10.2 24.1 27.3 18.0 11.0 17.7 31.0 11.5 17.6 23.0 10.8 45.0 13.6 11.4 7.5 12.4 15.2 12.6 27.0 20.3 9.8 10.1 15.9 13.4 6.3 17.2 8.5 15.4 20.8 13.1 26.0 23.1 11.0 21.5 22.3 1.5 0.2 0.3 1.4 0.1 1.2 1.0 1.0 1.0 0.3 1.1 0.6 1.0 1.2 1.7 0.2 0.4 2.2 0.7 1.5 1.2 2.2 1.5 1.6 0.7 0.6 0.4 0.7 0.1 0.8 1.0 1.3 0.0 2.7 2.0 1.8 2.8 6.2 3.7 5.2 1.6 2.8 3.4 1.3 2.8 3.4 3.7 0.0 7.6 2.5 1.7 0.0 7.3 9.1 2.5 1.2 2.5 0.0 10.7 4.4 2.2 9.7 2.6 4.1 2.4 2.5 9.4 1.4 0.5 4.5 1.7 3.1 2.3 10.2 0.9 1.6 6.7 0.6 1.2 5.4 1.9 1.5 1.5 5.2 1.0 2.5 2.2 0.2 0.0 4.4 4.6 0.4 0.3 3.1 2.6 6.6 3.4 2.5 14.4 11.8 7.4 2.4 2.5 2.4 0.5 4.7 3.4 CHAMP1 "C13orf8, CAMP, CHAMP, ZNF828" ENSG00000198824 "Chromosome alignment maintaining phosphoprotein 1" Q96JM3 13 114314482-114337626 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006623, HPA008900" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Midbody ring" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA006623: AB_1845548, HPA008900: AB_1845547" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (1.67e-1)" "unprognostic (3.89e-3)" "unprognostic (2.07e-1)" "unprognostic (9.43e-2)" "unprognostic (1.13e-1)" "unprognostic (4.38e-2)" "unprognostic (1.13e-2)" "unprognostic (4.40e-2)" "unprognostic (3.50e-2)" "unprognostic (3.67e-1)" "unprognostic (4.62e-2)" "unprognostic (2.40e-1)" 9.9 7.1 3.4 9.8 3.3 14.2 9.5 6.6 5.2 8.1 3.8 8.7 10.0 8.5 8.0 6.4 9.8 7.6 6.2 3.0 4.3 8.9 15.2 8.9 15.7 2.7 3.4 12.1 15.4 9.3 3.6 9.9 3.4 10.0 9.9 9.1 8.4 9.3 7.9 9.2 8.0 10.1 2.3 9.6 7.7 6.9 2.7 16.5 10.7 9.7 17.3 7.5 4.4 3.1 36.9 15.8 56.6 24.2 20.1 30.9 24.3 38.2 32.0 35.6 39.4 23.5 22.0 75.2 15.1 30.0 22.3 23.0 41.8 30.6 52.7 29.8 50.0 49.7 21.8 20.7 22.5 73.3 28.3 30.4 18.8 27.8 27.3 12.6 17.4 25.8 32.1 20.3 46.1 14.6 48.6 21.4 43.1 45.2 20.2 48.1 26.9 26.0 27.0 22.2 27.5 32.8 22.2 49.2 36.7 39.1 28.2 61.3 19.3 19.5 30.8 20.7 23.6 25.7 27.9 80.4 38.6 42.7 38.1 7.5 3.3 4.4 3.7 4.0 4.6 5.4 3.3 3.7 3.9 5.8 2.6 3.0 0.8 3.5 6.6 12.5 2.4 2.1 3.4 3.3 6.6 5.2 3.0 4.3 2.7 3.4 3.4 2.3 2.7 3.1 11.2 9.6 9.6 3.6 13.9 3.3 6.6 7.6 10.8 12.5 11.3 10.8 5.7 11.5 4.1 12.9 4.2 14.2 18.1 9.3 13.7 11.7 1.0 8.5 14.8 10.9 10.8 24.4 6.1 11.4 18.1 11.5 10.2 8.3 10.1 13.1 13.9 21.6 21.7 15.2 7.8 12.5 6.1 20.7 7.8 1.6 11.8 13.0 12.4 7.5 18.4 8.8 17.5 4.0 8.0 10.9 7.8 11.3 17.6 13.2 12.5 17.0 7.6 10.9 6.6 11.7 10.5 10.6 20.7 13.1 3.8 7.9 11.4 12.4 11.4 3.5 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625665-125676255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 20.7;seminal vesicle: 29.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Erythroid cells: 34.5;Extravillous trophoblasts: 35.6;Spermatocytes: 48.9;Spermatogonia: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 1.7;T-cells: 6.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 1.6 1.3 0.7 8.2 1.0 25.7 2.6 0.6 1.3 1.7 0.5 7.9 6.8 1.7 6.7 4.1 1.1 1.7 0.9 0.7 0.9 2.2 2.1 1.3 14.9 0.7 0.8 1.8 2.0 13.2 1.7 4.8 0.8 1.6 8.7 0.7 1.5 29.8 0.6 3.6 7.3 3.4 0.6 2.2 2.6 8.9 1.2 20.7 1.0 1.3 13.9 3.3 2.1 0.8 48.5 37.0 81.1 47.4 13.5 28.9 35.7 61.1 28.7 41.6 40.1 88.0 100.3 120.7 63.5 24.9 53.7 52.6 54.2 33.2 50.1 81.4 24.8 224.2 27.2 44.7 4.3 121.1 39.6 15.7 6.0 47.6 36.0 19.9 44.7 84.1 117.3 102.7 51.4 23.8 181.3 65.0 86.1 77.1 33.2 104.7 74.4 67.2 37.9 63.2 50.5 53.6 45.2 35.4 15.2 57.3 93.9 40.6 28.4 51.0 47.3 29.6 60.8 21.9 45.4 187.5 20.5 86.6 67.6 1.7 0.2 0.0 0.4 0.1 0.2 0.7 1.6 0.4 0.6 0.3 0.4 0.3 1.1 0.3 0.1 0.7 6.2 0.4 0.7 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.8 0.6 1.2 0.8 1.1 3.2 0.5 1.6 5.5 6.2 3.9 5.8 5.2 1.7 3.9 6.0 4.6 32.9 4.1 7.3 0.0 17.3 6.0 4.5 3.9 3.4 7.8 5.5 8.0 3.5 1.8 34.5 3.3 1.1 35.6 5.3 6.1 9.9 0.0 21.1 3.6 1.2 11.1 0.0 2.5 9.2 2.0 0.0 5.2 3.1 1.5 3.2 0.0 2.8 3.2 2.8 3.1 1.5 1.6 2.9 3.9 1.2 17.7 3.1 8.0 9.4 2.5 1.7 0.0 3.1 7.8 48.9 49.8 9.5 4.8 7.8 5.1 4.8 16.7 3.0 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 4.5 6.2 2.4 8.8 2.5 15.4 5.8 2.4 3.7 5.0 2.8 8.8 6.3 4.1 7.3 7.2 3.7 4.7 4.2 2.3 2.8 4.5 6.3 4.4 12.1 2.6 2.6 8.2 2.3 1.3 2.7 7.8 2.8 4.1 10.9 0.4 3.2 3.8 1.3 6.7 7.0 4.8 2.6 6.7 4.1 8.5 2.8 9.4 3.3 1.1 12.0 6.8 5.0 2.9 30.7 9.7 31.1 32.4 10.1 42.7 18.7 15.2 19.9 18.7 27.8 29.1 21.8 36.3 13.0 11.5 21.6 32.1 42.7 29.0 25.0 24.6 31.2 45.3 25.5 46.2 9.4 33.4 38.0 18.6 13.5 25.0 23.0 14.1 25.4 29.4 30.5 33.9 19.8 39.2 24.6 61.5 40.6 41.3 21.6 52.6 18.2 42.7 17.1 11.2 17.8 9.7 16.7 31.4 17.4 22.8 22.6 32.2 7.8 17.1 19.4 14.3 9.1 21.8 28.3 65.4 17.1 34.9 21.0 9.9 4.0 1.2 1.1 8.1 2.4 11.9 2.1 2.1 8.2 7.8 4.0 2.6 0.6 3.4 4.1 6.1 2.8 3.6 2.4 2.5 2.4 3.7 2.3 2.8 2.6 2.6 2.8 2.6 2.8 2.9 2.3 9.6 4.8 2.9 5.5 6.4 5.3 8.3 8.6 1.1 3.2 3.9 1.8 0.0 5.0 1.8 0.0 15.4 1.1 3.8 0.0 1.8 7.0 2.9 10.1 3.0 1.2 11.2 2.9 1.4 13.6 12.4 5.1 7.0 3.8 7.4 2.5 1.3 9.7 0.0 1.2 5.3 8.2 2.4 8.5 1.2 6.2 5.1 1.8 2.8 3.9 0.8 6.2 0.0 1.0 1.0 4.7 4.5 11.4 2.7 3.0 3.9 2.9 1.1 0.0 10.2 3.0 6.7 31.2 8.3 2.3 3.4 3.3 5.7 10.0 4.5 CHTF18 "C16orf41, C321D2.4, CHL12, Ctf18" ENSG00000127586 "Chromosome transmission fidelity factor 18" Q8WVB6 16 788046-800737 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.1;Extravillous trophoblasts: 19.6;Granulosa cells: 22.0;Spermatogonia: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 48.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA040976, HPA056209" Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA040976: AB_2677232, HPA056209: AB_2683066" "unprognostic (3.83e-2)" "unprognostic (4.97e-2)" "unprognostic (4.25e-2)" "unprognostic (9.35e-2)" "unprognostic (4.59e-2)" "unprognostic (3.02e-3)" "unprognostic (1.80e-3)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.19e-1)" "unprognostic (4.00e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (1.43e-8)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (9.89e-2)" "prognostic favorable (2.78e-4)" 2.7 2.2 0.7 1.1 0.5 6.8 3.2 0.7 1.5 4.3 0.0 3.3 1.9 3.2 0.0 5.1 3.2 0.6 1.8 0.7 0.4 2.6 2.4 2.8 1.4 0.5 0.3 4.8 2.8 0.1 2.5 1.2 0.5 3.4 0.3 0.3 2.7 0.6 2.0 4.0 4.0 0.3 0.1 5.7 3.0 11.7 0.5 1.8 3.1 0.3 0.3 3.1 3.7 0.4 14.4 7.0 5.5 4.5 0.5 0.4 48.3 8.9 2.4 4.4 3.0 12.5 10.8 16.1 8.9 1.5 2.3 15.7 1.2 6.8 0.0 9.2 20.1 7.1 8.6 6.4 0.0 4.4 13.4 0.2 0.8 4.2 2.2 0.6 3.7 16.4 10.9 5.2 1.1 27.7 17.4 16.6 7.2 3.3 8.3 31.1 14.0 21.2 1.5 4.1 7.2 9.2 6.4 14.1 4.8 0.6 10.3 10.8 2.4 6.5 23.5 11.8 12.2 12.3 4.3 9.1 2.0 6.5 11.5 2.5 0.2 0.0 0.7 1.0 0.4 0.1 0.3 0.6 0.4 0.2 0.4 0.1 0.1 0.7 0.6 0.2 0.4 0.2 0.7 0.5 0.7 1.5 0.7 0.4 0.5 0.3 0.5 0.1 0.5 0.4 4.3 3.2 4.2 2.6 3.5 5.4 3.3 2.7 5.7 23.1 4.1 5.5 4.6 0.0 3.0 1.8 2.1 15.2 4.3 7.1 1.9 2.9 1.2 4.2 4.9 2.4 6.6 14.3 2.3 3.9 19.6 3.9 10.2 8.8 4.5 22.0 3.3 2.4 6.4 6.7 1.8 5.3 0.0 2.6 5.8 1.3 1.8 2.9 0.0 2.8 0.3 2.4 2.1 1.5 2.8 1.8 1.0 1.5 5.7 1.4 0.9 1.0 2.5 7.0 0.0 3.2 3.5 13.6 21.2 4.5 2.0 8.6 3.4 5.0 7.4 3.2 CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.5;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 8.0;Exocrine glandular cells: 7.3;Extravillous trophoblasts: 12.9;Granulosa cells: 25.3;Hofbauer cells: 8.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039570 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA039570: AB_10796329" "unprognostic (2.02e-1)" "unprognostic (1.54e-2)" "unprognostic (2.31e-3)" "prognostic unfavorable (6.24e-5)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.91e-7)" "unprognostic (2.80e-3)" "unprognostic (2.53e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.18e-4)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (9.11e-3)" "unprognostic (3.73e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" 1.1 1.1 0.3 3.4 0.6 7.5 1.4 0.9 0.8 0.9 0.1 1.9 1.2 1.8 0.6 1.7 0.9 1.2 0.7 0.6 0.5 1.0 0.7 1.4 6.7 0.2 0.9 1.9 0.4 0.6 0.7 2.1 0.2 1.8 2.7 2.6 0.6 0.8 0.6 1.2 1.7 1.5 0.0 2.3 1.2 5.7 0.1 6.9 1.2 0.7 5.2 2.0 0.9 0.4 42.2 12.2 33.9 21.8 1.4 3.2 13.8 31.1 14.7 36.2 41.9 15.0 18.5 27.6 10.4 11.4 27.7 20.9 11.7 11.0 65.8 8.8 11.3 33.9 17.4 11.3 0.5 21.8 23.2 1.4 2.3 28.4 11.5 5.9 16.3 12.7 21.1 44.5 36.1 8.7 26.7 19.2 35.0 15.8 20.8 30.1 31.2 15.3 11.0 11.5 16.4 21.6 22.9 9.0 12.7 19.7 15.3 15.6 12.2 37.0 41.7 11.3 38.3 10.2 12.1 46.1 16.4 23.2 38.6 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.6 0.9 0.8 0.6 0.5 0.2 0.9 0.2 0.0 0.1 0.4 1.2 9.6 1.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 1.3 0.0 0.0 2.5 3.7 0.0 8.0 1.8 0.0 1.9 2.8 0.0 2.5 2.8 2.6 0.0 0.0 0.0 7.3 12.9 3.0 0.0 2.7 3.8 25.3 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.4 0.0 0.0 2.4 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.4 1.7 5.4 0.0 0.0 CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.9;Granulosa cells: 88.6;Spermatocytes: 151.7;Spermatogonia: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Enhanced "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Centrosome "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" 6.0 6.4 3.7 10.0 3.8 67.8 5.7 10.8 5.3 3.2 1.3 8.9 12.1 5.1 4.4 10.4 3.5 4.1 6.0 3.2 4.1 5.1 4.0 5.3 19.4 4.8 3.8 3.2 1.5 4.3 4.5 10.6 5.2 5.6 9.5 7.7 4.6 4.2 2.9 13.9 9.5 8.5 3.3 9.4 5.4 32.5 3.7 33.7 6.3 3.4 20.2 7.2 5.0 3.1 77.6 40.0 155.7 76.4 19.7 19.5 39.6 124.7 70.7 137.4 87.2 59.7 92.3 142.5 19.3 89.2 65.7 86.2 107.6 61.7 188.8 103.0 90.4 129.8 42.6 41.4 8.6 129.7 50.4 14.5 24.6 64.5 83.3 41.2 84.0 62.0 55.3 58.1 152.8 36.0 91.2 64.8 92.2 116.6 42.4 86.2 88.6 62.6 42.1 40.9 47.6 62.4 68.9 49.0 37.1 78.7 54.4 61.7 56.7 38.7 60.9 62.0 124.1 33.4 56.3 173.9 27.3 67.3 105.7 86.0 14.1 22.0 10.3 21.0 9.3 25.3 15.7 12.8 15.8 33.0 12.0 10.4 4.3 5.8 28.7 32.8 33.6 10.0 3.7 3.8 10.8 5.3 3.2 4.1 4.8 3.8 5.2 3.3 3.7 3.1 6.7 6.4 2.8 5.2 41.2 15.0 4.5 32.8 22.2 13.1 11.2 13.2 10.8 2.8 11.4 1.8 6.2 44.3 30.9 7.5 9.8 4.9 41.3 19.4 16.1 12.7 7.2 122.9 10.3 6.0 38.1 12.1 10.7 10.1 16.5 88.6 17.5 5.5 31.8 1.7 12.4 13.6 20.3 24.5 13.7 51.7 7.5 18.5 0.0 6.5 22.9 12.9 5.2 3.5 2.0 2.6 4.6 17.0 30.8 3.7 6.3 9.4 3.7 6.6 6.6 7.6 12.1 151.7 87.5 41.3 15.3 10.0 27.1 29.6 17.9 3.9 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.7;Spermatocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Centrosome" NA Yes 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centrosome" "Nucleoli, Nucleoli rim" "HPA039377: AB_10805477, HPA040375: AB_10794739" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-2)" "unprognostic (4.30e-3)" "unprognostic (3.77e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (4.69e-2)" 12.8 30.7 15.9 15.1 19.5 25.9 14.9 30.8 24.3 11.7 5.2 18.5 12.6 15.7 12.2 13.0 11.5 12.2 21.3 21.4 18.0 11.5 45.5 10.4 18.4 21.0 17.4 27.8 9.0 21.2 12.5 17.3 22.9 15.9 17.2 57.0 9.1 13.2 37.8 13.7 12.3 19.3 17.5 11.9 16.1 33.0 20.2 36.4 9.6 28.8 18.5 13.5 10.8 24.6 104.7 95.8 212.6 90.8 48.7 73.0 48.3 117.1 69.4 107.8 114.6 76.8 33.3 104.5 41.0 76.0 117.0 116.2 144.0 62.7 134.3 102.0 107.6 176.6 80.2 78.4 35.0 139.6 76.7 37.0 34.0 60.3 125.6 56.1 79.3 97.9 129.5 103.8 89.2 71.2 127.9 39.2 114.7 78.8 73.0 131.2 210.0 98.3 34.7 63.3 96.8 83.9 149.8 56.9 57.3 88.9 103.9 39.1 64.0 106.2 92.9 180.8 176.2 59.2 137.3 158.6 66.5 64.9 105.9 4.6 4.2 4.6 6.1 6.2 5.9 6.5 4.5 6.9 6.1 6.2 5.4 5.8 0.7 8.6 6.2 3.9 5.6 3.1 15.9 19.5 30.8 24.3 21.4 18.0 21.0 17.4 22.9 17.5 20.2 24.6 13.4 25.6 23.6 32.3 17.4 8.5 11.0 17.9 16.5 19.3 11.6 12.3 65.2 12.8 18.8 9.2 37.5 19.4 11.2 13.3 9.8 12.2 119.7 19.7 21.0 16.5 12.1 32.6 61.9 7.8 15.0 27.8 29.0 18.8 37.9 55.5 11.7 8.1 18.7 13.5 63.1 16.9 16.2 17.6 5.6 50.7 19.6 19.6 7.2 30.9 16.5 16.2 16.5 32.6 51.7 13.7 15.2 29.0 26.4 14.2 9.1 9.3 30.7 25.6 19.7 18.0 21.4 107.4 59.3 24.3 11.6 11.5 16.1 83.3 19.8 9.7 CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (1.06e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.34e-1)" "unprognostic (2.59e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.01e-3)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.63e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (3.19e-1)" "prognostic unfavorable (6.03e-7)" "unprognostic (3.12e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.37e-1)" 59.0 31.9 15.0 33.6 15.8 117.7 67.8 16.4 19.8 44.3 15.0 49.4 40.8 35.0 36.8 61.6 40.9 22.2 35.5 15.4 16.2 37.9 73.3 29.0 71.3 17.5 15.8 31.7 22.4 35.5 18.4 50.6 17.7 26.1 50.5 6.0 28.4 32.9 14.5 51.2 44.3 34.8 17.4 37.0 35.5 48.6 15.7 88.7 30.1 23.5 74.1 30.1 42.6 18.8 459.2 616.5 455.9 245.3 66.9 68.1 361.4 209.1 166.8 463.4 367.8 599.9 653.4 433.8 345.9 143.2 251.2 410.6 468.0 305.2 428.7 392.9 293.9 294.6 249.9 426.5 19.4 359.7 257.9 39.8 132.2 391.4 532.8 91.5 232.5 298.2 486.6 566.8 353.9 452.8 337.3 273.9 575.3 442.1 547.6 334.8 373.6 554.3 165.6 164.2 184.3 463.9 313.6 292.0 347.3 530.2 391.6 492.9 126.0 282.5 292.4 237.0 505.3 348.9 734.7 617.0 179.6 300.1 399.8 2.2 13.0 6.9 19.8 82.0 24.4 74.2 28.0 27.1 22.1 70.4 34.0 32.8 1.7 28.7 105.4 92.6 33.3 28.1 15.0 15.8 16.4 19.8 15.4 16.2 17.5 15.8 17.7 17.4 15.7 18.8 31.7 12.8 33.3 1.3 46.5 217.6 101.3 170.6 74.0 3.4 90.6 140.5 9.2 87.2 63.1 29.5 0.0 224.0 40.7 48.3 80.3 93.0 15.8 43.1 24.6 51.9 20.4 140.1 0.8 112.1 651.8 84.6 20.9 28.3 21.0 66.7 29.6 89.8 132.1 1.7 0.8 57.4 120.1 46.0 121.0 21.7 76.1 37.4 113.8 0.0 41.3 20.7 20.6 0.5 3.5 119.0 41.7 45.9 38.4 130.2 63.1 87.5 52.1 3.0 19.7 50.6 53.0 124.7 151.0 74.9 203.6 131.9 40.7 27.2 80.0 99.5 CLC "Gal-10, LGALS10, MGC149659" ENSG00000105205 "Charcot-Leyden crystal galectin" Q05315 19 39731255-39738029 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "bone marrow: 451.9" "Cell type enriched" "Detected in some" 15 "Erythroid cells: 127.8" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.0" "Not detected" "Not detected" "Group enriched" "Detected in all" 312 "basophil: 28756.2;eosinophil: 21481.0" "Lineage enriched" "Detected in all" 2254 "granulocytes: 28756.2" "Cell line enriched" "Detected in some" 12 "HMC-1: 7553.4" "Not detected" "Not detected" HPA041751 Enhanced NA NA 400000 "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA041751: AB_10793973" "unprognostic (4.53e-2)" "unprognostic (3.04e-2)" "unprognostic (4.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.72e-1)" "unprognostic (1.34e-2)" "unprognostic (6.60e-2)" "unprognostic (2.21e-1)" "unprognostic (4.28e-2)" "unprognostic (5.74e-2)" "unprognostic (1.24e-1)" 2.0 0.1 0.0 30.0 0.0 451.9 0.3 0.2 0.4 0.3 0.0 10.2 25.4 0.3 0.1 0.9 1.7 16.6 0.5 0.0 0.5 0.3 4.8 6.2 1.8 0.1 0.1 0.0 0.4 0.2 0.4 1.4 0.1 0.1 8.1 0.0 0.9 0.2 0.1 1.5 41.6 24.5 0.1 11.3 15.6 0.6 0.8 7.3 0.3 0.2 0.2 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 4.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 619.0 7553.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 3.5 0.7 0.9 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 2.3 0.0 0.0 3.8 0.0 2.4 28756.2 5.0 21481.0 2.5 11.1 6.0 4.8 6.9 1.7 5.3 6.2 3.1 9.2 80.3 2.5 12.7 7.8 4.0 100.3 0.0 0.0 0.2 0.4 0.0 0.5 0.1 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 127.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.3 0.2 0.0 0.0 0.0 COMMD4 FLJ20452 ENSG00000140365 "COMM domain containing 4" Q9H0A8 15 75336020-75343224 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039935, HPA066957" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Vesicles, Plasma membrane" "HPA039935: , HPA066957: AB_2685754" "unprognostic (7.77e-2)" "unprognostic (3.07e-3)" "unprognostic (1.03e-1)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (1.49e-1)" "unprognostic (2.60e-1)" "unprognostic (9.11e-2)" "unprognostic (1.78e-3)" "unprognostic (2.01e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-3)" "unprognostic (2.51e-1)" "unprognostic (2.27e-1)" "unprognostic (1.96e-1)" "unprognostic (5.07e-2)" 36.2 72.3 38.8 33.5 39.4 52.9 36.8 40.5 50.4 31.1 43.7 41.6 48.3 30.3 30.2 39.9 34.6 37.3 38.9 36.9 39.7 54.6 51.0 34.6 44.7 39.5 38.1 24.4 33.8 48.9 33.9 31.2 38.6 34.2 33.8 13.4 43.4 34.0 30.3 35.0 42.2 24.7 40.8 41.3 42.5 81.2 42.4 53.3 38.8 15.3 36.7 33.6 31.8 42.0 138.2 222.5 97.5 124.8 42.3 64.9 98.5 98.8 106.2 191.2 196.6 133.8 184.0 88.8 100.2 79.5 168.8 144.8 175.2 116.5 82.7 70.1 242.4 104.8 169.8 151.0 76.4 79.4 111.0 74.3 63.6 116.2 21.9 48.4 96.5 103.6 108.2 128.1 147.1 179.7 71.0 117.4 140.9 75.2 127.9 127.5 137.4 127.8 98.6 127.8 79.2 114.8 131.2 105.1 169.8 63.8 164.7 160.9 78.6 135.3 119.2 125.8 184.8 93.4 218.7 101.4 138.9 181.9 125.4 27.0 44.1 40.7 84.7 61.8 52.8 47.5 51.7 63.2 50.0 46.4 31.9 47.4 9.5 76.8 55.6 70.6 87.6 39.4 38.8 39.4 40.5 50.4 36.9 39.7 39.5 38.1 38.6 40.8 42.4 42.0 43.7 28.9 52.4 15.0 26.2 27.0 44.8 58.5 28.5 40.7 44.3 50.3 18.7 38.6 46.2 35.0 31.3 80.9 34.8 59.6 58.7 72.6 12.2 37.1 44.9 42.7 30.5 60.8 9.0 78.7 107.0 43.4 33.1 45.7 41.8 91.1 37.5 41.9 127.5 16.8 8.8 72.8 44.7 35.8 27.0 17.6 49.0 41.3 37.4 11.2 28.5 78.1 53.5 7.1 17.6 72.4 61.7 34.3 43.0 26.6 71.2 98.1 39.8 49.4 46.0 36.1 59.3 152.9 63.5 34.3 30.7 50.8 32.2 53.4 58.7 48.7 COPS3 "CSN3, SGN3" ENSG00000141030 "COP9 signalosome subunit 3" Q9UNS2 17 17246616-17281273 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 262.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021997, HPA050557" Approved Supported Nucleoplasm,Cytosol NA NA 38000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA021997: AB_1847152, HPA050557: AB_2681176" "unprognostic (3.35e-2)" "unprognostic (3.98e-3)" "unprognostic (1.84e-2)" "unprognostic (6.29e-2)" "unprognostic (6.39e-2)" "unprognostic (1.33e-1)" "unprognostic (2.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.91e-3)" "unprognostic (2.11e-2)" "unprognostic (6.37e-3)" "prognostic unfavorable (1.56e-4)" "prognostic unfavorable (8.65e-5)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (2.40e-1)" "unprognostic (3.03e-3)" 30.8 29.1 27.6 29.5 29.0 110.1 28.3 29.9 39.9 27.2 24.7 34.5 24.7 26.3 23.8 41.6 24.0 17.2 59.0 29.8 31.8 23.5 29.1 23.0 37.3 30.8 29.7 23.5 44.3 36.4 39.9 29.0 30.7 25.0 29.8 25.4 30.1 25.8 156.7 33.9 24.9 29.1 29.3 26.7 32.5 76.3 28.4 51.2 24.0 100.7 40.9 29.7 29.0 31.1 141.8 128.8 96.0 86.3 46.2 63.8 58.2 102.6 62.6 150.6 119.3 209.7 50.9 196.9 82.5 83.4 67.5 100.8 138.9 104.2 175.3 76.0 182.1 137.6 90.8 87.0 76.4 120.3 146.1 58.0 77.1 104.3 102.1 43.1 90.0 108.2 114.3 70.4 97.0 137.8 217.4 142.9 90.9 156.3 80.4 163.9 178.9 102.5 61.0 55.2 79.7 63.9 94.0 44.9 83.8 286.9 64.6 76.1 63.2 89.7 101.0 164.7 184.5 54.9 74.5 106.0 81.8 113.2 93.4 37.4 43.0 44.0 35.4 51.3 40.7 35.4 40.0 41.3 60.8 39.1 40.4 37.9 55.6 46.0 52.4 30.8 47.7 56.9 27.6 29.0 29.9 39.9 29.8 31.8 30.8 29.7 30.7 29.3 28.4 31.1 32.0 32.1 19.1 11.1 52.7 54.2 43.3 69.0 33.0 23.2 31.1 27.8 50.5 34.3 38.6 14.7 14.6 95.1 52.2 17.1 33.2 52.8 136.1 27.4 30.1 33.3 37.6 117.0 13.6 51.2 84.5 37.5 21.4 33.5 40.0 26.7 22.9 23.1 67.0 25.2 16.3 37.3 44.7 36.4 52.3 79.2 39.7 43.6 35.6 11.2 60.0 41.3 53.5 13.6 16.0 33.4 18.6 38.0 65.6 43.0 27.4 36.6 25.5 38.0 19.7 52.5 49.9 262.3 109.8 50.1 47.6 104.4 51.3 43.9 43.3 36.5 COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 37.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 50.7;Kupffer cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056599: AB_2683184, HPA068727: AB_2686022" "unprognostic (8.26e-2)" "unprognostic (7.40e-3)" "unprognostic (3.95e-3)" "unprognostic (1.55e-1)" "unprognostic (9.22e-2)" "unprognostic (5.59e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.56e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (2.46e-1)" 6.0 17.0 2.8 8.0 3.2 11.8 5.8 3.5 3.3 7.9 3.6 14.2 9.5 6.3 7.5 10.4 4.4 4.3 15.0 3.0 3.5 5.6 13.6 7.9 6.4 3.6 3.5 6.5 6.5 6.0 4.0 8.4 3.8 6.6 14.2 4.0 7.8 5.0 29.1 10.8 9.1 6.9 4.1 10.1 5.5 3.5 3.9 3.6 5.7 37.5 7.1 7.9 6.5 4.9 26.1 14.7 14.1 27.4 10.5 11.9 9.7 16.1 27.0 29.7 34.4 10.5 38.7 17.2 11.7 28.4 24.6 18.6 23.9 26.0 38.7 17.2 14.8 15.3 22.3 15.4 11.7 31.3 73.5 15.9 16.3 14.2 24.8 8.9 30.7 9.7 10.0 21.4 29.3 27.4 8.6 21.7 10.9 30.6 19.9 14.1 11.4 22.1 45.4 13.8 10.3 6.3 19.0 24.5 9.2 6.7 15.4 18.8 21.0 14.6 14.6 11.1 23.4 5.7 5.2 10.2 29.5 36.8 20.2 2.1 28.8 4.0 2.7 26.8 1.9 6.2 3.0 2.5 21.1 6.9 2.1 3.2 9.8 6.7 33.5 11.2 4.1 13.6 2.8 3.2 3.5 3.3 3.0 3.5 3.6 3.5 3.8 4.1 3.9 4.9 5.4 0.0 4.2 15.7 11.5 6.6 12.4 9.8 4.6 5.9 6.3 5.6 19.5 2.8 10.7 9.2 0.0 25.4 7.1 14.0 31.3 6.7 0.8 7.6 19.5 6.1 4.8 14.1 12.8 10.8 30.0 9.0 6.6 9.2 0.0 17.2 9.3 15.0 50.7 1.7 20.1 15.3 8.2 53.2 7.9 0.8 3.7 25.2 7.2 33.7 21.8 12.6 6.2 25.6 15.6 5.4 15.4 4.9 4.3 12.6 11.0 9.9 6.2 4.8 0.0 7.3 9.7 18.1 19.7 16.7 12.6 12.4 9.6 35.5 26.7 12.9 CSE1L "CAS, CSE1, XPO2" ENSG00000124207 "Chromosome segregation 1 like" P55060 20 49046246-49096960 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 164.0;Spermatogonia: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002140, HPA038059, HPA038060" Enhanced Enhanced Nucleoplasm,Cytosol No Yes 320000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB002140: AB_563461, HPA038059: AB_2675811, HPA038060: AB_2675812" "unprognostic (4.01e-2)" "unprognostic (3.15e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.91e-5)" "unprognostic (4.86e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-8)" "unprognostic (3.44e-2)" "unprognostic (1.45e-2)" "unprognostic (2.63e-2)" "unprognostic (2.72e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (2.59e-1)" "unprognostic (4.84e-1)" "unprognostic (5.71e-1)" "prognostic unfavorable (6.91e-4)" 23.6 24.5 16.0 29.0 20.2 26.4 34.2 26.6 21.1 25.7 12.9 23.6 19.8 28.1 23.8 38.2 27.0 19.0 24.7 17.1 18.0 29.8 30.9 19.7 35.0 21.0 17.3 27.2 20.4 30.8 13.6 37.5 22.8 25.8 28.7 23.2 21.7 25.6 39.8 34.4 19.2 35.0 21.1 20.3 20.7 87.7 17.0 40.7 23.4 41.5 42.8 27.5 22.2 29.1 224.3 152.4 182.1 140.9 69.0 88.5 196.7 172.1 90.5 528.1 222.0 501.8 175.4 227.3 224.1 109.7 213.9 251.4 270.7 322.9 500.0 37.4 131.3 158.0 166.1 244.7 42.0 176.2 83.3 50.0 118.7 259.0 148.7 72.4 177.5 124.3 227.2 87.1 201.1 76.8 213.9 90.6 153.5 185.1 224.0 133.9 299.5 176.4 116.5 153.2 159.6 92.6 275.2 293.3 97.1 137.7 245.3 113.3 115.5 279.3 233.9 166.4 247.9 50.5 130.8 210.8 166.8 139.5 152.2 18.6 16.3 3.8 13.8 20.6 21.1 16.7 21.0 17.1 20.1 13.6 22.1 19.3 4.4 23.0 23.6 8.9 20.1 18.3 16.0 20.2 26.6 21.1 17.1 18.0 21.0 17.3 22.8 21.1 17.0 29.1 16.4 6.4 26.8 8.1 20.3 30.2 25.8 29.5 31.3 14.9 17.4 15.9 26.6 24.3 22.4 27.6 10.4 71.8 15.7 7.4 13.7 32.2 95.9 14.7 19.4 22.9 5.4 40.4 20.9 26.6 61.2 24.6 13.7 17.8 4.5 35.1 19.2 26.7 29.7 15.2 24.4 11.8 20.3 17.9 21.9 57.8 25.4 17.9 26.6 9.4 28.0 22.6 7.2 17.1 41.7 26.7 10.0 31.6 26.7 28.8 9.9 21.6 21.7 15.5 39.5 19.3 22.1 164.0 121.5 36.7 34.5 72.7 17.5 31.1 23.7 22.2 DARS2 "FLJ10514, mtAspRS" ENSG00000117593 "Aspartyl-tRNA synthetase 2, mitochondrial" Q6PI48 1 173824653-173858808 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026506, HPA026528" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria Nucleoplasm "HPA026506: AB_1847482, HPA026528: AB_1847483" "unprognostic (3.14e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-3)" "unprognostic (4.10e-3)" "unprognostic (2.20e-1)" "unprognostic (1.42e-1)" "unprognostic (6.17e-2)" "unprognostic (1.15e-1)" "prognostic favorable (1.74e-4)" "unprognostic (3.30e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (4.73e-3)" 8.8 9.8 3.1 7.6 3.5 5.4 7.5 3.7 4.3 7.1 11.5 14.6 8.7 4.3 4.7 6.4 5.2 4.8 8.4 3.1 3.8 19.9 13.5 5.7 9.2 3.3 3.6 4.4 5.7 15.5 2.9 7.6 3.4 5.3 15.4 5.2 5.2 5.0 5.6 3.4 10.4 5.6 3.5 6.2 9.3 6.2 3.9 10.6 7.6 13.5 12.0 6.7 4.1 3.7 74.8 50.5 26.3 18.7 24.0 34.2 38.6 32.3 30.0 49.2 37.0 47.5 68.2 41.6 45.2 27.2 31.3 77.5 86.6 56.5 66.7 48.6 41.5 35.2 22.7 31.8 24.0 30.9 30.8 23.2 25.3 50.9 44.5 15.4 49.8 30.5 74.7 31.0 39.6 19.9 38.8 16.1 60.2 83.0 63.2 44.3 40.6 78.2 43.7 24.9 40.4 34.2 36.3 79.6 51.3 47.0 84.5 39.7 21.2 22.9 35.3 32.6 52.5 21.7 60.4 46.3 13.3 33.3 51.5 3.9 4.4 3.3 3.8 7.0 5.4 6.0 3.4 3.2 6.4 4.4 3.8 2.6 0.2 3.5 5.0 2.5 3.9 3.5 3.1 3.5 3.7 4.3 3.1 3.8 3.3 3.6 3.4 3.5 3.9 3.7 3.7 3.2 3.1 7.2 5.7 1.8 4.1 3.1 6.2 2.3 3.3 2.5 12.6 4.3 4.2 5.5 0.0 9.7 3.1 4.8 7.9 3.9 2.5 3.9 4.9 4.5 4.2 9.4 5.3 2.7 16.0 3.9 7.1 4.5 5.7 4.5 1.8 5.4 10.3 3.3 6.5 5.2 0.0 4.4 2.2 1.5 3.1 5.1 1.8 8.4 5.6 2.9 3.1 4.0 5.1 3.8 1.9 1.5 7.1 2.6 5.9 7.1 3.0 2.7 0.0 6.2 4.0 8.9 7.1 8.0 1.6 4.2 4.4 9.2 7.2 2.9 DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;testis: 10.8" "Cell type enhanced" "Detected in many" "Plasma cells: 8.2;Spermatocytes: 17.2;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA038540: AB_10672648, HPA038541: AB_2676071" "unprognostic (2.53e-1)" "unprognostic (2.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (3.86e-6)" "unprognostic (4.65e-3)" "unprognostic (1.01e-3)" "unprognostic (8.24e-3)" "unprognostic (2.04e-4)" "unprognostic (4.72e-2)" "unprognostic (1.11e-16)" "unprognostic (7.17e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-1)" "unprognostic (9.13e-2)" 0.9 0.4 0.6 3.3 0.9 7.9 2.1 0.9 1.0 0.7 0.4 1.8 1.6 1.2 1.0 2.9 0.5 0.7 0.5 0.8 0.4 0.4 1.2 3.4 4.4 0.8 0.8 0.5 0.9 0.1 0.1 1.9 0.7 0.5 2.2 0.5 0.8 0.4 1.0 2.2 1.5 1.8 0.5 2.9 0.9 10.8 0.8 5.3 0.4 0.9 6.2 3.5 0.9 1.8 13.6 22.6 21.0 15.2 1.9 3.1 15.3 25.4 10.5 26.8 31.0 22.4 16.2 16.1 36.1 5.7 21.6 24.7 36.0 15.5 36.8 30.7 19.7 23.1 10.6 9.1 0.2 28.6 19.7 0.7 1.4 33.8 15.6 2.3 12.8 20.5 23.9 27.0 23.9 19.6 27.0 23.2 25.1 36.5 24.4 20.0 40.5 20.6 5.7 23.3 15.6 21.5 15.2 15.6 5.7 20.2 16.5 11.7 6.0 26.7 35.9 71.1 30.4 15.4 44.3 56.4 8.4 20.2 26.3 0.7 10.3 4.1 0.5 7.9 0.2 1.1 0.3 0.7 4.5 1.7 0.6 0.4 5.5 2.2 8.5 1.4 0.5 3.2 0.6 0.9 0.9 1.0 0.8 0.4 0.8 0.8 0.7 0.5 0.8 1.8 0.3 0.0 0.0 0.0 4.3 0.0 0.6 0.0 1.8 0.0 1.1 1.1 0.9 1.5 0.0 0.0 0.0 2.7 1.0 0.6 0.0 0.9 4.2 1.0 0.6 0.8 0.0 6.5 0.6 0.6 5.5 0.8 1.1 1.2 0.0 2.5 0.7 0.7 2.5 0.0 0.3 0.7 0.0 6.4 0.0 1.9 0.3 3.5 0.0 1.9 4.5 0.0 4.1 0.5 0.6 0.5 0.1 0.7 8.2 0.7 0.3 0.3 0.0 0.0 0.0 0.8 1.1 17.2 18.2 5.4 0.0 0.3 1.5 0.5 1.6 0.9 DDX11 "CHL1, CHLR1, KRG2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073860-31104799 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065197 Supported Supported Nucleoplasm,Nucleoli No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065197: AB_2685430" "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (4.87e-2)" "unprognostic (3.89e-3)" "unprognostic (3.53e-1)" "unprognostic (5.66e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.23e-8)" "unprognostic (1.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" 5.9 6.4 6.0 10.2 6.8 29.2 7.2 6.9 7.3 10.7 7.1 9.6 8.0 7.5 4.3 9.5 8.0 5.9 5.3 6.0 6.1 9.2 9.3 6.1 13.2 6.9 6.4 11.0 17.5 5.8 9.4 5.4 6.9 10.0 10.1 6.6 8.6 5.3 10.6 16.7 13.4 3.6 6.1 13.8 9.6 8.8 6.7 24.0 8.0 6.6 11.1 6.9 9.8 6.9 36.5 35.0 42.2 34.5 5.8 11.0 58.7 21.8 10.4 25.2 28.5 44.1 58.6 49.2 23.9 10.8 23.6 35.0 31.7 28.9 21.3 43.4 66.6 47.4 71.0 25.4 2.1 37.4 35.0 11.9 13.0 32.6 24.8 16.9 12.6 55.2 26.6 103.3 17.6 30.9 64.5 60.7 84.0 39.9 19.5 55.0 53.3 66.2 13.3 38.5 30.2 21.7 23.4 33.2 10.4 65.0 27.3 25.5 8.2 22.0 42.1 42.2 40.0 39.4 29.6 95.3 24.6 32.5 20.3 0.0 1.3 0.8 2.0 1.2 1.5 2.5 1.9 1.5 1.5 2.6 2.0 2.6 0.5 2.2 4.4 2.4 2.0 1.3 6.0 6.8 6.9 7.3 6.0 6.1 6.9 6.4 6.9 6.1 6.7 6.9 10.1 3.2 9.5 1.6 9.0 6.0 4.0 6.0 2.2 9.4 8.3 7.1 2.5 4.3 6.0 0.0 14.6 7.6 8.8 7.8 0.0 2.0 1.7 5.5 8.9 5.4 0.0 15.3 2.5 3.3 7.5 5.7 9.7 7.4 5.7 15.6 6.1 7.7 5.2 8.4 3.6 6.5 10.2 4.1 5.4 1.3 7.2 4.4 7.2 3.7 3.5 2.7 4.1 1.5 1.7 3.2 2.7 4.5 17.2 6.0 2.3 1.4 6.7 25.8 0.0 4.9 4.8 5.3 18.0 5.5 6.5 2.6 8.4 4.1 9.5 5.1 DDX39A "BAT1L, DDX39, DDXL, URH49" ENSG00000123136 "DExD-box helicase 39A" O00148 19 14408798-14419383 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 147.8" "Cell type enhanced" "Detected in many" "Early spermatids: 308.4;Late spermatids: 283.3;Spermatocytes: 307.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055334 Approved Approved "Nuclear speckles" NA NA 200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "HPA055334: AB_2682787" "unprognostic (1.31e-1)" "prognostic favorable (6.86e-4)" "unprognostic (2.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (5.20e-2)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.81e-2)" "unprognostic (1.64e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (1.50e-10)" "unprognostic (1.55e-3)" "unprognostic (8.57e-2)" "unprognostic (3.92e-1)" "unprognostic (7.38e-3)" 28.2 21.6 17.1 49.6 20.7 105.5 24.7 21.9 23.0 22.1 18.0 26.4 28.6 21.9 8.7 39.3 18.2 13.6 24.9 17.0 18.6 21.0 21.9 25.1 76.2 21.9 19.8 14.9 15.7 10.2 15.5 18.1 22.0 16.8 20.2 4.7 19.0 8.8 20.7 24.4 33.8 15.1 19.0 55.7 27.2 147.8 20.5 80.4 20.5 12.7 65.1 25.9 22.7 25.2 198.8 175.9 87.8 147.2 32.4 22.4 73.5 84.8 48.0 176.1 105.7 183.3 98.7 375.0 87.5 71.1 101.0 114.8 215.7 135.9 74.3 129.0 127.3 408.5 201.0 133.1 55.1 225.1 164.0 30.1 30.6 113.1 47.0 25.4 89.1 134.4 253.4 150.3 95.7 270.9 375.4 320.1 147.9 208.8 280.4 248.9 139.7 212.0 62.5 179.6 181.5 98.2 64.3 127.8 98.6 54.3 138.0 216.5 83.1 144.5 92.7 245.7 192.6 156.0 313.0 399.3 167.1 232.2 148.9 33.2 92.8 29.6 120.1 107.9 106.2 132.5 96.0 96.3 131.1 125.8 83.1 90.1 27.0 84.1 94.3 82.7 153.0 135.5 17.1 20.7 21.9 23.0 17.0 18.6 21.9 19.8 22.0 19.0 20.5 25.2 55.6 16.0 21.4 4.9 90.0 76.0 43.6 53.0 50.1 10.5 30.0 24.8 10.9 21.5 27.4 5.5 0.0 60.6 75.1 60.5 37.2 55.3 308.4 26.6 30.6 53.0 25.7 88.1 3.1 67.2 117.9 33.3 87.7 44.5 93.0 32.7 26.0 12.9 90.5 11.8 3.5 55.4 26.4 48.6 85.2 283.3 26.4 62.7 49.8 4.7 56.7 16.2 50.4 4.0 9.2 53.5 42.7 18.8 115.6 44.5 41.7 26.0 21.1 4.9 19.7 24.8 62.0 307.5 95.4 69.4 71.0 59.9 78.7 32.1 63.8 34.2 DEK D6S231E ENSG00000124795 "DEK proto-oncogene" P35659 6 18223860-18264548 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015226, HPA054505, HPA057799" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015226: , HPA054505: AB_2682508, HPA057799: AB_2683530" "unprognostic (6.35e-2)" "unprognostic (6.11e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (3.66e-1)" "unprognostic (5.02e-3)" "prognostic unfavorable (9.65e-4)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.61e-3)" "unprognostic (6.49e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (2.31e-1)" "unprognostic (3.78e-1)" 50.8 43.0 17.3 82.4 20.1 158.6 63.1 29.6 25.4 48.1 19.8 74.8 76.9 74.2 29.9 65.4 45.6 49.0 61.0 17.3 18.3 46.0 68.0 53.2 125.5 19.5 20.4 61.4 40.3 43.3 19.3 67.7 20.8 56.2 74.2 46.3 37.3 56.1 116.0 49.8 86.8 63.9 18.2 63.8 58.7 22.1 19.5 116.8 102.3 73.4 112.8 59.3 43.0 26.1 450.1 118.6 330.9 276.6 68.9 118.4 184.2 347.4 210.9 338.9 457.1 190.7 165.5 504.2 390.2 181.8 269.1 251.1 260.7 196.2 591.3 346.5 221.3 305.7 179.9 260.0 70.3 499.2 238.2 58.2 98.1 238.2 198.2 164.7 170.9 188.1 392.9 0.6 236.5 156.2 380.3 222.1 208.6 177.4 131.8 471.7 459.7 299.8 184.2 239.6 196.1 183.8 328.9 290.5 224.6 218.4 277.8 212.7 168.7 382.7 220.0 223.9 474.1 32.4 77.0 540.3 95.0 251.3 380.8 116.2 78.2 41.8 69.6 74.9 83.1 66.3 72.5 78.0 72.9 56.1 55.6 55.7 93.4 70.9 92.9 49.0 75.2 67.8 17.3 20.1 29.6 25.4 17.3 18.3 19.5 20.4 20.8 18.2 19.5 26.1 149.7 121.8 130.8 16.3 126.2 271.2 189.8 128.8 146.3 70.3 143.3 161.3 218.8 161.5 112.0 79.1 81.3 284.2 174.5 156.7 82.2 172.0 17.4 118.8 157.7 156.6 88.5 448.8 10.4 173.1 235.4 159.6 85.1 170.6 111.2 195.1 105.7 125.1 190.9 26.9 18.6 188.1 67.1 185.3 300.7 26.2 189.5 219.1 101.4 31.9 263.3 136.2 212.1 26.2 37.1 136.9 117.3 191.5 44.0 252.9 140.0 129.5 89.0 138.8 210.4 189.1 197.0 87.2 220.7 169.9 233.6 108.6 189.1 138.6 232.5 209.2 DEPDC1 "DEP.8, DEPDC1A, FLJ20354, SDP35" ENSG00000024526 "DEP domain containing 1" Q5TB30 1 68474152-68497221 "Predicted intracellular proteins" "Transcription, Transcription regulation" "GTPase activation, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.1;testis: 8.1" "Cell type enhanced" "Detected in many" "Early spermatids: 44.9;Erythroid cells: 31.8;Extravillous trophoblasts: 35.2;Late spermatids: 73.0;Spermatocytes: 86.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017845 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB017845: " "unprognostic (2.73e-1)" "unprognostic (7.40e-2)" "prognostic favorable (8.70e-5)" "unprognostic (1.23e-3)" "unprognostic (3.06e-1)" "unprognostic (7.73e-3)" "unprognostic (4.37e-6)" "unprognostic (3.39e-3)" "unprognostic (1.57e-3)" "unprognostic (8.59e-2)" "unprognostic (9.04e-6)" "unprognostic (2.18e-1)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (2.27e-1)" "unprognostic (2.83e-2)" "unprognostic (1.11e-1)" 0.3 0.1 0.0 2.6 0.0 5.0 0.6 0.0 0.1 0.4 0.0 2.9 2.5 0.5 0.1 2.4 0.1 0.5 0.1 0.1 0.0 0.0 0.4 0.2 4.8 0.0 0.1 0.0 0.0 0.2 0.0 3.2 0.1 2.1 3.5 0.0 0.3 0.1 0.0 1.6 2.4 1.5 0.0 0.6 1.2 8.1 0.2 8.1 0.3 0.2 4.8 0.9 0.7 0.2 47.2 21.5 40.0 18.5 2.5 5.6 31.3 58.9 26.9 49.1 42.1 17.9 19.3 0.0 42.8 24.4 78.6 30.8 58.6 30.7 82.4 41.2 38.2 38.3 35.9 10.5 0.6 33.4 0.0 2.1 1.6 56.3 31.2 10.0 36.0 16.5 26.6 36.1 88.3 10.7 0.1 12.5 34.6 19.5 28.9 0.0 118.7 15.3 19.8 12.7 44.8 20.7 59.0 24.9 30.3 25.6 22.5 16.6 21.3 31.5 35.5 56.0 69.2 22.5 52.2 0.5 29.7 11.4 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 3.3 0.8 3.3 1.2 0.4 1.3 1.8 0.8 0.0 0.5 1.8 0.0 20.6 0.4 2.1 0.0 0.2 44.9 4.0 1.6 1.6 0.0 31.8 0.5 0.0 35.2 4.4 8.2 2.0 0.0 17.5 2.2 1.2 8.6 0.0 2.2 5.3 4.1 3.5 1.0 73.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 6.9 2.2 0.5 0.1 0.9 0.2 0.0 0.6 4.0 86.8 19.6 12.2 1.3 2.9 1.6 0.5 8.8 1.7 DEPDC1B "BRCC3, XTP1" ENSG00000035499 "DEP domain containing 1B" Q8WUY9 5 60596912-60700190 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.1;gallbladder: 21.0;lymphoid tissue: 20.7;testis: 12.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 18.6;Erythroid cells: 23.8;Extravillous trophoblasts: 21.6;Spermatocytes: 37.2;Syncytiotrophoblasts: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038255, HPA072558" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA038255: AB_10669521, HPA072558: AB_2686534" "unprognostic (1.38e-1)" "unprognostic (1.99e-2)" "prognostic favorable (2.42e-4)" "prognostic unfavorable (8.55e-4)" "unprognostic (2.23e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (3.08e-4)" "prognostic unfavorable (6.93e-5)" "unprognostic (2.13e-2)" "unprognostic (8.14e-2)" "unprognostic (1.47e-3)" "unprognostic (2.44e-2)" "unprognostic (1.11e-16)" "unprognostic (1.00e-1)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (8.62e-2)" 0.3 0.2 0.4 3.9 0.7 11.1 0.9 0.5 0.5 0.6 0.1 4.1 6.0 0.6 0.0 2.5 0.2 21.0 0.1 0.3 0.6 2.9 0.4 0.4 9.1 1.2 0.5 0.2 0.1 0.0 0.0 7.5 1.4 0.2 5.5 0.1 0.5 0.1 0.0 2.1 6.4 0.9 0.6 1.6 1.4 12.6 0.6 20.7 1.2 0.0 9.7 1.0 1.1 1.5 61.0 20.3 60.5 37.2 1.3 1.9 66.2 16.1 10.9 27.7 35.8 34.0 37.5 34.6 38.5 5.0 36.0 19.8 49.2 36.1 36.9 49.5 35.5 43.3 22.7 42.6 1.0 36.7 40.3 1.2 3.7 9.0 12.9 5.4 26.1 36.3 31.4 45.8 24.7 38.0 59.8 31.9 44.7 13.0 32.6 65.4 49.2 29.4 22.8 29.9 33.6 15.4 37.7 13.4 17.7 27.0 24.9 28.8 12.1 11.7 34.2 9.5 41.6 23.0 43.3 68.0 14.7 53.2 33.3 1.5 0.1 0.9 0.2 0.0 0.2 0.4 1.0 0.7 0.3 0.0 0.1 0.1 0.0 0.6 0.0 0.0 3.2 0.4 0.4 0.7 0.5 0.5 0.3 0.6 1.2 0.5 1.4 0.6 0.6 1.5 0.2 0.0 1.8 0.0 1.9 4.7 1.0 1.5 0.0 0.1 0.5 0.8 0.1 18.6 0.3 0.0 0.0 7.4 1.1 3.1 0.0 0.3 1.9 3.3 1.4 0.9 0.0 23.8 5.5 0.2 21.6 1.1 2.6 11.7 3.8 5.2 0.0 0.3 6.4 0.0 1.7 2.3 0.0 1.6 2.9 2.4 0.3 1.9 0.0 4.7 0.1 0.2 0.0 2.0 7.0 0.9 5.8 0.0 15.9 0.7 3.7 1.0 0.1 0.1 6.6 0.3 1.4 37.2 12.7 5.8 2.0 46.9 4.5 0.6 7.9 0.9 DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626226-80654983 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.8;Spermatocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Approved Mitochondria NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "CAB037129: AB_439683, HPA051465: AB_2681494" "unprognostic (1.44e-2)" "unprognostic (1.03e-2)" "unprognostic (2.24e-3)" "unprognostic (2.91e-3)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-2)" "unprognostic (2.35e-2)" "unprognostic (2.02e-2)" "unprognostic (4.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" 25.2 5.3 15.3 20.7 16.5 54.3 12.0 15.8 21.9 8.0 13.3 21.4 24.5 8.6 7.0 14.1 7.4 8.5 7.2 13.8 15.5 21.3 60.1 7.5 41.5 16.6 16.6 6.6 3.2 9.1 6.3 14.4 16.6 8.9 25.3 10.3 6.8 9.5 19.6 9.8 25.1 12.0 16.5 10.3 12.2 18.5 15.8 60.7 8.2 25.8 39.5 10.3 5.7 17.7 98.1 66.6 164.8 122.7 30.7 32.0 60.6 76.5 58.1 130.2 149.0 63.8 114.6 196.9 32.5 44.6 106.0 67.0 214.4 98.6 208.5 88.2 132.1 94.8 104.5 59.5 6.6 111.7 40.3 22.3 9.9 116.9 13.0 22.2 63.9 142.0 108.3 146.7 133.5 98.2 276.5 44.9 83.6 48.3 38.5 176.7 323.3 194.1 75.1 61.5 134.3 93.7 107.9 49.9 54.6 83.5 98.5 108.6 38.5 41.0 62.0 116.0 148.3 68.2 146.6 210.3 91.5 222.1 107.7 0.2 0.3 0.2 0.5 0.6 0.2 0.5 0.6 0.8 0.5 0.5 0.5 0.6 0.8 0.5 0.5 0.8 0.9 0.6 15.3 16.5 15.8 21.9 13.8 15.5 16.6 16.6 16.6 16.5 15.8 17.7 4.1 6.4 11.7 4.9 21.4 6.9 6.5 6.0 4.0 3.5 8.9 8.9 13.0 4.3 6.1 14.7 2.1 35.2 7.4 19.3 9.8 7.4 7.4 10.8 7.7 7.7 4.9 145.8 7.3 3.7 47.3 12.0 11.7 8.0 2.5 22.0 10.0 48.3 44.7 3.3 7.2 19.1 4.1 18.9 4.4 6.4 14.0 12.8 0.0 4.7 7.1 14.5 13.4 3.5 6.0 4.7 10.3 16.1 60.9 2.9 26.6 40.0 6.9 3.2 13.1 9.0 12.5 132.2 49.8 21.2 5.5 13.3 11.8 12.3 38.1 12.1 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.7;lymphoid tissue: 42.0;testis: 17.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 92.6;Extravillous trophoblasts: 23.1;Plasma cells: 22.1;Spermatocytes: 68.1;Spermatogonia: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 0.8 0.3 1.4 8.1 0.9 29.7 1.4 0.4 1.8 0.8 0.6 5.5 5.0 1.3 0.1 5.2 0.4 0.8 0.2 1.0 1.7 0.2 0.7 0.7 17.9 0.7 1.0 0.2 0.1 0.2 0.0 4.1 0.8 0.2 6.7 0.1 0.8 0.1 0.1 3.1 4.6 2.7 0.3 2.6 3.0 17.4 1.1 42.0 0.4 0.0 18.7 2.0 1.5 3.8 144.8 56.8 140.6 63.7 3.3 13.4 43.8 80.3 52.7 115.3 109.3 45.9 75.8 82.1 44.2 46.9 47.4 85.6 91.5 64.0 150.5 101.9 45.7 84.4 49.9 39.3 0.4 82.7 49.3 2.8 2.2 54.8 27.0 18.9 129.0 82.5 70.5 79.8 109.3 69.2 105.0 42.7 72.6 63.3 57.3 80.8 137.9 39.0 37.9 45.2 71.7 40.7 84.8 31.7 30.8 60.6 71.6 31.6 49.6 52.4 133.3 50.6 94.6 19.4 44.9 108.9 35.9 59.6 83.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.9 1.4 0.3 0.0 0.2 0.1 0.2 1.0 0.0 0.0 5.4 0.7 1.4 0.9 0.4 1.8 1.0 1.7 0.7 1.0 0.8 0.3 1.1 3.8 0.1 0.0 0.5 0.0 4.4 1.1 0.7 3.3 0.0 0.0 1.2 0.9 0.4 0.0 1.3 0.0 0.0 11.6 1.4 3.2 0.0 0.4 19.7 7.2 2.6 2.4 0.0 92.6 0.3 0.0 23.1 4.2 7.7 4.5 0.0 15.8 3.9 0.5 10.5 0.0 0.3 3.6 8.2 4.1 1.6 6.0 0.9 3.7 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.2 1.2 22.1 0.6 0.3 0.1 1.3 0.0 6.6 0.0 3.8 68.1 31.7 11.6 0.4 1.9 4.0 0.9 6.9 1.4 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.2;Excitatory neurons: 14.1;Inhibitory neurons: 15.5;Oligodendrocytes: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.3 0.9 1.9 2.8 2.1 4.6 1.8 2.5 3.6 1.4 1.0 2.3 2.1 1.1 0.9 1.9 0.9 0.9 1.8 1.8 1.9 2.6 4.2 1.8 5.2 2.3 1.9 1.2 1.6 0.4 1.5 1.6 2.4 1.9 2.8 5.3 1.6 0.4 1.6 1.8 3.2 1.1 1.6 2.1 1.9 2.9 2.1 8.1 1.0 0.9 4.2 1.4 1.4 3.2 25.6 13.0 29.0 20.7 3.2 2.2 20.4 12.4 10.3 17.4 21.2 31.1 16.1 26.1 4.6 3.8 6.7 15.2 16.8 6.5 20.7 16.2 12.6 15.8 8.5 12.3 0.9 27.7 16.4 1.8 2.6 12.3 3.6 4.5 7.9 17.0 23.6 22.8 10.1 9.0 42.8 19.8 20.5 10.9 24.0 33.1 20.0 8.4 7.5 11.7 13.1 15.7 16.9 21.4 4.2 20.1 16.5 11.6 3.4 6.6 20.5 8.5 23.8 11.5 13.9 38.3 5.7 26.1 8.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 1.9 2.1 2.5 3.6 1.8 1.9 2.3 1.9 2.4 1.6 2.1 3.2 1.0 6.4 1.1 4.9 1.3 2.3 0.9 1.7 2.8 2.5 2.3 1.4 10.5 2.8 1.1 1.8 6.2 3.9 2.2 1.7 0.0 0.8 2.2 2.0 1.4 2.0 1.2 33.2 14.1 0.9 4.8 2.0 2.6 2.8 0.0 6.0 0.7 4.6 2.2 0.0 15.5 1.8 0.0 1.3 0.7 3.7 0.6 1.5 0.0 4.7 0.5 0.5 2.1 5.5 18.4 0.7 0.1 0.7 7.4 2.5 2.4 0.6 0.8 4.3 0.0 2.4 1.1 9.1 12.2 4.7 1.7 1.2 1.6 0.7 3.7 1.0 DNAJC9 "JDD1, SB73" ENSG00000213551 "DnaJ heat shock protein family (Hsp40) member C9" Q8WXX5 10 73183362-73247255 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 173.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035215, HPA035216" Supported Supported "Nucleoplasm,Plasma membrane" NA NA 39000 "Cluster 44: Non-specific - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA035215: AB_10603663, HPA035216: AB_2674522" "unprognostic (4.18e-2)" "unprognostic (1.61e-2)" "unprognostic (7.63e-2)" "unprognostic (2.67e-3)" "unprognostic (3.45e-1)" "unprognostic (6.83e-3)" "unprognostic (2.43e-3)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.20e-2)" "unprognostic (1.66e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (7.07e-5)" "unprognostic (5.61e-2)" "unprognostic (3.08e-3)" "unprognostic (6.49e-2)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" 9.2 10.6 17.1 17.6 17.5 91.9 15.4 19.2 21.5 11.2 15.4 16.0 14.6 12.8 12.4 16.9 9.7 6.9 8.6 16.9 17.0 10.0 13.4 9.6 28.2 16.4 16.5 15.3 8.7 10.2 10.6 17.6 16.9 11.4 18.0 25.1 11.3 11.2 11.5 17.7 13.9 11.8 15.7 14.8 12.2 12.4 17.0 35.8 8.4 13.1 32.3 11.5 11.9 17.6 135.0 77.3 93.8 68.4 16.1 19.3 45.7 101.5 59.4 101.1 106.1 130.8 89.4 86.9 33.5 43.6 43.7 83.1 92.9 67.5 118.1 98.5 63.8 188.3 79.4 93.4 14.8 173.1 71.0 14.8 33.2 107.1 93.4 36.4 66.2 112.1 168.3 103.0 81.4 118.4 155.0 124.7 36.3 64.4 215.1 114.2 85.1 47.6 52.9 61.5 44.3 73.4 73.5 114.5 52.9 43.7 62.1 76.8 48.0 65.2 118.3 71.3 168.0 45.0 70.6 141.8 64.8 162.9 45.9 23.9 3.7 29.1 25.5 10.7 29.2 32.8 31.3 28.2 6.5 28.3 30.3 26.9 4.5 24.8 10.9 20.3 36.8 18.0 17.1 17.5 19.2 21.5 16.9 17.0 16.4 16.5 16.9 15.7 17.0 17.6 17.3 9.6 12.3 11.1 39.5 47.7 34.1 31.9 33.0 26.1 21.5 24.8 2.7 17.2 24.8 9.2 8.4 107.8 44.6 18.3 21.5 31.5 80.4 15.9 14.0 20.6 12.0 173.8 11.8 31.4 111.4 17.6 12.2 19.0 42.3 26.0 13.9 9.8 61.9 15.2 12.8 25.6 54.9 10.9 19.6 43.3 14.0 17.4 32.0 6.5 23.0 29.5 32.0 7.5 6.5 44.1 16.7 20.3 49.7 27.6 18.2 16.3 21.9 43.2 26.3 17.7 28.3 28.7 65.4 38.2 43.5 58.0 45.2 19.7 38.0 37.5 DONSON "B17, C21orf60, C2TA, DKFZP434M035" ENSG00000159147 "DNA replication fork stabilization factor DONSON" Q9NYP3 21 33559542-33588706 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 57.3;Erythroid cells: 42.1;Spermatocytes: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039558, HPA049033" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cell Junctions" Cytosol "HPA039558: AB_2676570, HPA049033: AB_2680608" "unprognostic (9.90e-3)" "unprognostic (1.01e-3)" "unprognostic (6.58e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (8.22e-4)" "unprognostic (4.00e-2)" "unprognostic (5.93e-3)" "prognostic favorable (2.17e-4)" "unprognostic (1.25e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.77e-2)" "unprognostic (1.66e-1)" "unprognostic (2.07e-1)" "unprognostic (8.83e-2)" 5.5 2.9 5.8 5.5 6.5 10.9 4.1 7.9 7.5 8.5 4.2 5.2 5.4 5.7 2.4 5.0 7.0 5.5 4.4 5.4 6.5 3.9 7.9 4.6 10.5 6.7 6.2 10.8 3.4 5.6 5.5 6.6 6.7 4.8 6.3 13.3 3.5 3.4 4.4 8.5 6.1 4.5 5.7 3.6 4.9 21.2 6.5 10.6 3.5 4.8 9.2 4.7 6.2 8.6 67.9 15.5 34.8 30.4 10.7 18.5 23.9 53.7 23.2 41.2 45.1 41.9 19.7 40.5 13.9 28.3 30.6 20.0 43.6 20.2 45.1 36.5 36.5 73.8 34.9 41.5 8.1 39.0 18.2 13.9 5.7 44.4 11.1 13.1 25.1 19.8 67.0 65.2 35.4 14.7 34.0 17.2 35.9 34.8 17.3 33.2 68.4 41.3 21.3 19.0 36.0 14.8 82.1 25.3 23.1 17.1 34.9 19.4 16.4 38.0 25.3 28.6 37.7 56.8 58.1 59.3 22.1 52.1 43.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 6.5 7.9 7.5 5.4 6.5 6.7 6.2 6.7 5.7 6.5 8.6 6.3 3.2 1.9 10.4 4.8 8.2 8.1 3.1 5.2 2.8 5.6 5.7 3.9 7.2 2.3 3.7 10.4 13.2 7.8 3.0 1.9 3.3 57.3 3.0 6.6 8.0 1.2 42.1 9.7 4.7 27.9 6.9 7.1 4.4 8.2 7.5 7.5 6.2 8.9 6.7 11.2 4.2 6.1 3.4 6.3 25.3 10.2 5.5 7.2 4.7 4.0 2.1 4.1 7.5 12.7 3.9 2.5 13.9 19.3 5.7 2.9 4.4 2.8 3.6 0.0 4.4 7.6 62.3 33.5 7.6 9.8 16.6 7.6 3.0 6.8 9.2 DSCC1 "DCC1, hDCC1, MGC5528" ENSG00000136982 "DNA replication and sister chromatid cohesion 1" Q9BVC3 8 119833976-119855894 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.6;Extravillous trophoblasts: 17.6;Spermatogonia: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023780, HPA024401" Uncertain Approved Nucleoplasm NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023780: AB_2671311, HPA024401: AB_2671557" "unprognostic (7.36e-3)" "unprognostic (8.24e-2)" "unprognostic (1.56e-1)" "unprognostic (4.71e-3)" "unprognostic (9.91e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.92e-6)" "prognostic unfavorable (3.93e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (3.24e-3)" "unprognostic (8.12e-3)" "unprognostic (2.72e-2)" "unprognostic (2.32e-9)" "unprognostic (2.75e-2)" "unprognostic (5.01e-1)" "unprognostic (4.40e-2)" "unprognostic (8.18e-2)" 1.8 1.8 1.3 3.7 1.6 6.1 2.4 2.1 2.0 2.6 1.1 2.7 2.4 2.4 1.3 2.4 1.5 1.0 1.5 1.4 1.4 0.9 1.1 1.4 7.1 1.5 1.5 1.5 2.8 0.5 0.5 2.3 1.6 1.9 3.5 0.3 3.7 1.2 2.1 2.6 2.3 2.7 1.5 1.3 1.7 2.6 1.4 9.9 1.0 3.4 5.7 1.5 2.1 1.8 34.3 16.6 32.1 29.4 4.6 8.3 13.8 23.1 4.7 16.3 16.9 15.2 20.4 61.7 19.7 6.9 10.1 24.8 36.7 14.4 17.5 42.2 33.3 78.7 16.2 17.9 1.5 31.2 26.4 3.8 2.2 20.1 9.7 3.8 4.7 40.5 27.2 26.9 19.9 33.8 82.4 19.2 47.2 90.4 41.2 29.1 30.4 29.9 12.7 21.3 28.7 17.6 12.4 96.7 15.8 25.0 18.1 17.0 3.2 17.7 48.0 17.2 33.9 36.5 58.2 65.4 9.0 49.2 26.2 0.0 0.0 0.0 0.9 0.0 0.7 0.3 0.2 0.4 0.0 0.1 0.1 0.3 0.0 0.8 0.0 0.2 0.3 0.2 1.3 1.6 2.1 2.0 1.4 1.4 1.5 1.5 1.6 1.5 1.4 1.8 4.7 0.0 0.5 2.6 1.2 3.4 2.2 2.1 4.6 0.7 2.2 3.2 0.8 1.5 0.2 0.0 0.0 7.9 1.6 1.0 0.0 1.6 0.1 0.8 2.8 3.0 0.0 24.6 6.4 2.4 17.6 4.3 1.5 1.3 4.5 3.7 4.6 0.9 4.7 0.0 5.2 1.2 2.0 1.0 1.2 0.2 1.2 0.9 3.6 1.0 0.0 1.5 1.0 7.5 5.3 0.5 0.3 2.6 5.2 1.7 0.2 1.5 1.7 0.3 0.0 2.3 3.3 1.1 18.8 6.0 3.3 1.4 3.0 2.0 3.8 1.5 DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.8;Spermatocytes: 115.5;Spermatogonia: 75.1;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: AB_1078343, HPA030627: AB_2732460" "unprognostic (3.60e-2)" "prognostic favorable (4.49e-4)" "unprognostic (5.22e-3)" "unprognostic (1.13e-3)" "unprognostic (2.00e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (4.16e-5)" "unprognostic (3.93e-1)" "unprognostic (9.35e-2)" "unprognostic (5.51e-2)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.92e-2)" "unprognostic (2.53e-1)" "unprognostic (2.58e-2)" "unprognostic (2.84e-1)" 5.9 9.9 4.2 7.5 4.2 14.3 8.6 3.9 4.5 5.0 5.2 9.2 6.8 4.4 9.3 7.9 4.1 4.4 5.1 4.3 4.4 4.8 9.1 6.3 12.8 4.0 3.9 4.3 4.3 5.5 3.5 8.8 4.1 6.5 10.8 10.7 5.9 6.3 4.0 8.0 7.8 6.3 3.9 9.6 7.3 23.3 4.1 16.4 5.1 4.8 14.3 4.4 4.7 4.7 36.7 29.1 35.7 29.5 14.0 18.0 24.7 42.9 35.1 63.9 70.2 52.5 44.4 39.3 27.4 23.0 69.1 45.8 33.3 32.7 60.3 18.2 22.7 78.3 26.2 36.1 3.0 46.2 34.0 7.0 9.4 43.7 13.8 10.4 31.5 42.4 30.9 33.7 41.7 25.3 59.2 34.5 16.8 63.3 55.1 46.1 109.4 28.4 16.2 20.5 37.8 16.9 52.9 53.7 25.8 26.3 55.9 30.5 16.4 60.1 35.0 56.9 46.1 27.3 39.1 46.4 49.8 40.8 42.6 53.4 6.4 14.5 7.4 11.0 8.4 14.6 8.1 10.3 7.1 18.4 10.1 9.0 11.9 11.1 10.1 46.9 12.2 6.7 4.2 4.2 3.9 4.5 4.3 4.4 4.0 3.9 4.1 3.9 4.1 4.7 6.5 6.4 4.4 1.6 10.3 5.0 11.4 7.6 3.4 8.0 8.7 7.6 5.4 2.8 8.6 5.5 29.2 49.8 9.8 9.2 7.9 6.8 10.6 5.5 5.9 8.1 2.4 22.1 6.3 6.4 30.4 8.4 20.9 9.4 3.8 21.8 7.9 6.2 14.7 6.7 4.4 13.6 4.1 6.3 4.6 8.0 8.7 6.7 1.8 5.6 7.4 6.0 7.2 3.0 3.6 5.1 5.4 7.5 22.9 7.1 7.7 3.6 8.2 17.5 0.0 5.3 8.2 115.5 75.1 12.3 7.2 47.5 7.7 6.9 13.6 11.0 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 14.6;intestine: 4.7;lymphoid tissue: 14.2;placenta: 3.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.3;Erythroid cells: 36.2;Extravillous trophoblasts: 16.2;Spermatocytes: 53.2;Spermatogonia: 20.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 0.6 0.2 0.0 4.1 0.0 14.6 1.9 0.0 0.1 0.6 0.0 3.3 2.3 1.1 0.1 1.9 0.4 0.4 0.1 0.0 0.0 0.1 1.2 1.4 5.6 0.0 0.1 0.1 0.1 0.5 0.2 3.9 0.0 0.4 4.7 0.0 0.4 0.1 0.1 2.1 3.0 1.9 0.0 2.5 1.3 13.7 0.1 14.2 0.5 0.0 6.4 1.2 0.7 0.0 34.1 28.1 48.0 23.6 2.9 5.8 23.3 41.3 25.5 38.1 56.1 17.6 29.0 25.2 15.4 16.1 25.0 25.8 62.5 34.9 54.7 31.4 30.9 40.7 33.6 21.5 0.1 54.1 25.3 2.5 1.2 62.2 32.4 6.8 17.7 44.7 49.1 51.1 44.4 13.5 75.3 24.3 56.6 25.2 32.9 57.2 84.0 49.2 11.6 22.9 29.6 46.0 39.2 37.5 17.6 47.7 32.0 24.1 9.7 38.2 28.6 40.5 47.8 18.4 30.5 57.7 19.1 35.5 37.8 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.3 2.3 0.4 1.7 0.0 0.0 1.3 1.3 7.0 1.5 0.9 0.0 0.0 12.8 1.4 1.5 0.0 0.4 25.3 0.4 1.3 5.2 0.0 36.2 0.2 0.0 16.2 2.4 3.1 1.0 0.0 11.4 0.7 0.4 4.7 0.0 0.3 3.3 0.0 0.3 0.8 12.4 1.2 2.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.6 0.4 0.0 12.8 0.2 0.6 0.0 0.1 0.0 0.0 0.2 2.7 53.2 20.8 5.6 1.7 1.5 2.6 1.6 5.2 0.7 DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675747-241686944 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 108.6;Extravillous trophoblasts: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria NA NA 7000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA042593: AB_10959590, HPA042719: AB_10960633" "unprognostic (1.90e-1)" "unprognostic (6.95e-2)" "unprognostic (4.14e-1)" "unprognostic (8.61e-2)" "unprognostic (1.89e-1)" "unprognostic (9.45e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (2.64e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-2)" "unprognostic (6.94e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (7.13e-2)" "unprognostic (6.81e-2)" "unprognostic (5.07e-2)" "unprognostic (9.19e-2)" 12.2 16.0 15.6 15.6 17.1 37.0 11.8 16.2 19.8 11.2 16.5 15.1 13.2 10.8 6.1 19.1 10.2 8.6 10.6 14.5 15.0 14.9 18.8 9.7 24.8 16.8 16.0 8.2 9.5 7.5 5.0 11.1 16.1 11.1 12.2 4.3 9.8 7.4 8.1 18.8 14.0 13.4 15.3 17.2 13.3 8.2 16.8 24.1 8.7 6.4 19.2 10.6 11.2 17.2 102.6 112.3 93.6 120.1 30.2 33.3 103.2 82.1 63.2 110.8 125.6 54.8 120.1 48.3 24.6 66.8 126.8 84.4 87.8 102.2 56.7 118.8 104.6 103.9 88.3 105.1 26.3 69.1 83.1 23.7 27.3 102.7 42.4 32.1 104.8 74.4 123.6 38.4 114.1 112.6 132.2 125.0 100.7 113.1 94.2 111.4 139.8 71.8 62.3 59.5 115.0 74.0 53.4 81.5 67.9 27.0 74.2 120.0 66.5 147.5 110.4 99.0 152.5 47.3 49.1 144.6 122.4 112.2 184.9 20.5 26.2 17.4 30.4 46.7 29.6 35.6 28.5 32.6 19.7 36.7 28.1 25.0 4.2 32.6 37.1 38.5 42.1 28.5 15.6 17.1 16.2 19.8 14.5 15.0 16.8 16.0 16.1 15.3 16.8 17.2 28.9 9.6 5.8 8.1 21.4 15.2 17.7 47.7 16.5 19.1 36.3 44.8 11.0 24.3 22.2 25.8 2.1 79.5 24.0 22.9 21.5 39.6 2.1 17.6 25.0 29.2 14.4 108.6 3.3 34.1 149.1 26.9 25.5 22.3 15.2 52.3 23.9 22.3 84.9 5.0 4.7 35.7 36.7 17.0 13.9 2.1 16.4 21.7 23.2 5.6 39.3 23.0 38.1 6.0 9.2 33.7 10.6 19.2 37.6 21.7 12.7 37.7 12.9 17.4 26.3 21.4 31.2 27.5 63.4 32.6 11.9 27.5 17.4 28.2 52.2 19.5 DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm No Yes 31000 "Cluster 26: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054422: AB_2682483, HPA060360: AB_2684262" "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (7.89e-2)" "unprognostic (5.27e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (4.42e-3)" "unprognostic (1.87e-2)" "unprognostic (4.25e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-2)" "unprognostic (4.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-2)" "unprognostic (1.71e-2)" 73.0 65.3 54.7 61.7 58.9 162.9 76.4 57.1 77.2 90.7 60.0 69.5 29.3 76.9 49.7 72.1 77.6 33.6 68.9 53.9 59.6 67.6 53.6 58.1 97.8 58.2 55.5 86.1 53.2 48.3 80.0 45.1 58.3 77.8 47.1 49.1 66.5 48.3 57.9 71.6 66.5 40.4 57.7 82.1 61.5 57.3 57.5 111.4 89.2 53.0 87.8 69.1 78.0 63.5 196.1 60.2 143.9 137.1 98.4 104.0 85.3 202.1 128.1 182.8 224.6 69.8 131.0 539.3 106.0 112.0 149.4 262.1 152.4 138.4 177.6 383.4 157.2 442.2 151.8 96.1 54.8 469.0 202.0 64.4 92.1 123.9 65.0 117.8 123.3 316.6 244.0 297.6 136.5 79.3 422.4 548.7 90.7 197.4 114.5 338.6 313.9 570.0 120.8 130.4 207.2 210.1 150.0 119.6 184.4 145.5 169.6 368.6 103.0 190.1 183.1 228.3 269.7 238.1 534.3 532.5 143.6 789.4 213.4 32.5 50.3 46.8 52.9 53.1 68.7 94.8 94.7 84.6 74.0 90.0 97.4 64.3 30.9 60.5 68.4 85.3 94.3 71.4 54.7 58.9 57.1 77.2 53.9 59.6 58.2 55.5 58.3 57.7 57.5 63.5 153.6 54.5 38.9 39.8 126.8 179.6 212.0 222.4 131.5 48.3 158.0 205.5 120.1 95.8 118.5 104.8 14.6 221.8 103.9 62.8 203.5 94.3 36.8 67.2 123.5 123.0 96.1 418.8 36.5 46.5 286.8 147.9 76.5 86.0 84.4 118.3 101.4 77.6 174.5 82.4 32.1 98.4 105.8 87.7 112.6 31.5 184.8 92.0 154.7 23.4 89.5 106.3 95.8 23.6 45.1 45.4 58.8 177.6 192.3 133.2 27.2 256.4 59.6 40.9 157.8 167.1 154.0 508.7 270.0 206.4 168.5 97.1 124.4 82.3 195.4 181.2 DYTN ENSG00000232125 Dystrotelin A2CJ06 2 206651621-206721570 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "Erythroid cells: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (3.23e-3)" "unprognostic (8.52e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 E2F1 "RBBP3, RBP3" ENSG00000101412 "E2F transcription factor 1" Q01094 20 33675477-33686385 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.0;Granulosa cells: 11.4;Spermatogonia: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000329, HPA008003, CAB019308, HPA029735" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 22: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Centrosome" "CAB000329: AB_627476, CAB019308: , HPA008003: AB_1847936, HPA029735: AB_2673176" "unprognostic (7.46e-2)" "prognostic favorable (9.22e-6)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.33e-5)" "unprognostic (1.51e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.83e-5)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.15e-2)" "prognostic unfavorable (8.99e-5)" "unprognostic (1.05e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.62e-4)" "unprognostic (1.91e-1)" 1.8 5.5 7.1 5.6 7.1 34.3 1.6 5.2 9.2 1.8 3.9 3.8 3.2 1.2 0.2 5.7 1.3 0.7 1.4 6.1 5.6 0.9 1.8 3.7 8.7 7.6 6.4 3.5 1.0 1.3 0.6 2.4 6.5 1.9 3.9 0.7 1.9 0.9 1.6 4.7 4.1 2.8 7.0 5.0 3.7 10.4 6.9 10.7 0.8 0.8 6.9 2.4 2.5 8.3 48.1 45.4 52.0 40.5 5.2 3.6 39.3 45.0 21.4 55.9 46.7 81.1 48.0 87.3 44.2 20.2 67.7 35.4 25.3 23.8 24.8 26.4 36.5 71.6 71.9 47.7 0.4 34.0 43.6 2.8 1.4 30.6 5.4 5.7 14.6 54.4 19.3 60.0 34.9 42.3 72.8 71.6 15.6 47.9 64.6 71.4 140.7 36.2 9.6 28.7 76.7 54.1 54.6 37.6 22.7 14.8 47.3 42.4 7.9 65.0 37.7 45.8 64.8 58.1 42.0 72.6 54.1 20.0 39.3 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.1 0.1 0.1 7.1 7.1 5.2 9.2 6.1 5.6 7.6 6.4 6.5 7.0 6.9 8.3 1.1 0.0 1.1 0.7 3.6 2.9 1.7 0.5 0.0 2.3 3.1 4.3 0.4 0.0 1.4 0.0 0.0 5.0 2.9 2.4 0.0 0.9 1.0 0.3 1.0 1.6 0.0 25.0 1.5 0.2 9.6 3.0 7.7 1.2 0.0 11.4 0.7 0.8 4.4 0.0 0.5 4.6 2.0 0.6 2.1 3.1 2.1 3.1 1.8 1.0 0.1 1.5 1.0 1.0 3.4 0.6 0.5 1.2 9.7 0.5 1.4 0.1 0.2 2.3 0.0 1.0 3.0 7.5 32.9 3.7 1.7 1.8 3.3 1.2 7.0 3.5 E2F2 E2F-2 ENSG00000007968 "E2F transcription factor 2" Q14209 1 23506438-23531233 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 25.1;esophagus: 8.7;lymphoid tissue: 15.8" "Group enriched" "Detected in many" 4 "Early spermatids: 50.2;Erythroid cells: 45.7;Late spermatids: 110.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 46.7;Karpas-707: 38.9;U-266/84: 37.2;U-698: 38.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB016313 Uncertain NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "CAB016313: AB_2096794" "unprognostic (3.14e-2)" "unprognostic (5.74e-3)" "unprognostic (1.31e-3)" "unprognostic (4.18e-2)" "unprognostic (8.54e-2)" "unprognostic (1.70e-3)" "unprognostic (6.43e-6)" "unprognostic (7.83e-3)" "unprognostic (1.53e-2)" "unprognostic (7.33e-2)" "unprognostic (1.51e-3)" "unprognostic (1.86e-2)" "unprognostic (0.00e+0)" "unprognostic (1.00e-3)" "unprognostic (2.82e-1)" "unprognostic (8.67e-3)" "unprognostic (1.84e-1)" 0.2 0.2 0.0 1.8 0.0 25.1 0.1 0.1 0.1 0.9 0.1 3.4 1.5 0.1 0.0 8.7 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.8 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.1 2.1 0.0 0.8 0.0 0.1 3.5 2.1 0.3 0.0 5.1 0.7 3.6 0.1 15.8 0.2 0.0 3.7 0.3 1.9 0.1 5.4 3.9 6.4 10.2 0.2 0.2 4.5 2.5 1.2 2.4 3.1 2.5 3.1 46.7 3.0 1.3 1.1 10.6 12.9 0.6 2.2 11.8 4.2 7.4 10.7 2.8 0.0 5.4 9.3 0.0 0.1 1.7 0.2 0.3 0.7 21.4 5.8 38.9 1.1 3.2 24.3 5.0 1.4 5.8 1.9 26.4 13.7 15.7 0.9 1.4 8.3 11.6 4.3 5.4 1.3 0.8 4.0 3.9 0.5 2.2 6.1 7.0 3.6 28.5 37.2 38.0 2.1 5.8 4.3 4.1 0.2 0.8 0.0 0.6 0.0 0.4 0.3 0.2 0.5 0.3 0.0 0.0 0.1 0.1 0.9 0.4 1.3 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.4 0.8 0.2 0.2 1.8 0.0 1.0 1.3 0.6 0.0 0.3 1.8 0.0 3.4 0.7 14.5 0.0 0.1 50.2 0.3 0.3 0.6 1.2 45.7 0.1 0.0 4.8 1.1 3.1 1.1 0.0 4.2 0.4 0.4 2.3 0.0 0.1 5.9 0.0 3.1 0.8 110.3 0.3 2.7 0.0 1.0 1.4 0.0 0.0 0.5 0.1 0.1 7.3 0.4 14.5 0.6 1.8 0.1 0.0 0.0 0.0 0.1 0.8 2.5 5.2 10.2 1.0 0.5 1.7 0.7 9.5 1.3 E2F8 FLJ23311 ENSG00000129173 "E2F transcription factor 8" A0AVK6 11 19224063-19241620 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;lymphoid tissue: 11.8;skeletal muscle: 12.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 34.1;Gastric mucus-secreting cells: 10.2;Plasma cells: 9.7;Squamous epithelial cells: 10.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA064882, HPA076614" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytosol" "HPA064882: AB_2685381, HPA076614: " "unprognostic (5.62e-2)" "unprognostic (5.24e-2)" "unprognostic (3.17e-2)" "unprognostic (6.99e-3)" "unprognostic (2.86e-2)" "unprognostic (1.66e-2)" "unprognostic (1.29e-5)" "unprognostic (1.94e-2)" "unprognostic (3.90e-3)" "unprognostic (2.41e-1)" "unprognostic (7.29e-4)" "unprognostic (1.16e-2)" "unprognostic (9.13e-8)" "unprognostic (1.02e-3)" "unprognostic (1.37e-1)" "unprognostic (3.81e-1)" "unprognostic (4.28e-3)" 0.3 0.1 0.0 2.8 0.0 14.2 0.5 0.1 0.1 1.0 0.0 4.0 3.8 0.4 0.0 4.9 0.9 0.4 2.1 0.0 0.0 0.1 0.3 0.3 7.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.4 5.1 0.0 0.9 0.2 12.6 3.0 3.0 0.6 0.0 1.3 5.6 1.7 0.0 11.8 0.1 0.4 7.3 1.8 1.3 0.1 23.3 7.2 7.1 9.8 0.4 1.1 31.7 13.0 3.7 15.3 16.4 25.4 7.8 23.5 5.5 4.3 9.0 20.2 17.2 1.6 13.5 15.9 14.9 8.0 4.1 7.1 0.0 12.7 19.2 0.3 0.1 3.1 1.0 0.9 21.0 17.2 17.6 22.1 6.3 11.6 25.8 16.6 6.9 26.3 10.1 26.9 12.8 16.0 6.6 16.8 6.0 7.0 5.5 11.3 1.3 4.0 7.7 13.7 4.2 7.3 9.0 18.3 11.8 7.7 16.2 30.6 9.0 24.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 1.1 0.1 1.3 0.0 0.0 0.3 0.1 3.8 0.0 0.5 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.4 3.3 0.8 0.8 1.2 34.1 0.1 0.0 1.7 1.0 10.2 3.3 0.0 3.1 0.0 0.0 2.4 0.0 0.0 3.9 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 1.2 0.0 9.7 0.1 0.4 0.2 5.6 0.0 0.0 1.5 0.9 4.0 3.1 10.0 0.3 0.3 2.2 0.5 6.3 0.9 ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Spermatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA036363: AB_2732472, HPA053261: AB_2682094" "unprognostic (3.83e-2)" "unprognostic (4.34e-1)" "unprognostic (1.27e-2)" "unprognostic (4.22e-3)" "unprognostic (4.49e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.82e-6)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.82e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" 3.6 3.3 2.1 8.2 1.9 19.8 7.5 3.4 3.4 8.1 1.4 11.5 9.3 4.4 1.8 8.9 3.3 5.3 3.2 2.4 1.4 4.3 2.6 5.2 10.5 2.1 1.7 1.3 2.9 3.6 1.2 8.8 2.7 3.2 15.8 12.5 5.6 2.6 2.1 7.1 7.6 7.5 0.7 4.3 9.4 15.9 2.3 23.3 3.9 2.7 11.4 6.9 4.2 3.5 192.0 133.6 103.2 54.0 10.6 21.8 51.6 81.5 67.5 121.4 116.9 74.7 196.9 47.2 122.1 48.8 116.0 81.8 84.2 53.1 164.3 67.8 46.6 29.6 70.0 38.5 4.6 46.2 32.8 7.1 9.0 72.2 73.2 34.0 53.0 68.6 31.3 67.2 97.2 67.6 47.5 34.6 84.4 156.7 72.0 33.7 101.1 60.7 92.2 43.7 68.6 44.1 104.5 117.4 42.2 51.5 195.4 34.1 46.5 58.5 55.7 79.6 174.9 32.8 47.2 88.2 51.6 39.7 78.0 6.0 2.0 0.7 1.0 1.7 1.1 1.4 1.4 0.9 1.6 1.3 0.6 0.9 6.3 0.7 0.7 1.6 2.5 0.7 2.1 1.9 3.4 3.4 2.4 1.4 2.1 1.7 2.7 0.7 2.3 3.5 6.7 6.4 3.2 4.2 3.8 19.5 4.9 6.2 9.1 3.4 10.1 6.5 3.6 5.7 5.7 3.7 64.6 12.0 2.9 10.7 0.0 9.5 3.3 20.1 6.6 7.7 4.8 25.2 6.5 9.2 14.9 6.0 17.9 20.5 0.0 17.9 5.3 2.9 7.3 0.0 2.5 13.5 10.2 4.7 6.3 2.8 0.9 5.1 7.2 15.0 2.8 3.1 2.1 3.0 4.9 20.7 3.8 1.5 9.6 12.8 1.5 3.7 11.0 16.3 0.0 2.9 5.2 42.6 30.4 16.9 12.8 3.8 4.1 3.3 13.5 8.8 EME1 "FLJ31364, MMS4L, SLX2A" ENSG00000154920 "Essential meiotic structure-specific endonuclease 1" Q96AY2 17 50373220-50381483 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.4;epididymis: 6.3;testis: 5.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.6;Extravillous trophoblasts: 4.8;Granulosa cells: 4.5;Spermatocytes: 13.2;Spermatogonia: 9.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "basophil: 18.6" "Lineage enriched" "Detected in single" 33 "granulocytes: 18.6" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016127, HPA052188" Supported Approved "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Cytosol" "CAB016127: AB_2278026, HPA052188: " "unprognostic (3.81e-1)" "unprognostic (7.72e-2)" "unprognostic (6.49e-2)" "unprognostic (2.45e-3)" "unprognostic (2.74e-1)" "unprognostic (1.94e-2)" "unprognostic (9.94e-5)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.02e-2)" "unprognostic (4.37e-3)" "unprognostic (2.83e-3)" "unprognostic (0.00e+0)" "unprognostic (9.82e-2)" "unprognostic (1.26e-1)" "unprognostic (3.71e-1)" "unprognostic (3.41e-1)" 0.5 0.3 0.2 1.7 0.3 4.4 0.6 0.1 0.4 0.5 0.0 0.9 0.8 0.4 6.3 1.1 0.3 0.3 0.2 0.1 0.1 0.2 0.4 0.4 2.3 0.3 0.2 0.5 0.2 0.1 0.1 1.4 0.3 0.2 1.3 0.4 0.5 0.1 0.2 1.1 0.7 0.6 0.1 0.9 0.5 5.7 0.3 3.3 0.2 0.0 2.6 0.4 0.5 0.4 13.9 20.0 26.2 13.7 1.2 2.6 18.8 14.2 5.4 19.3 17.7 31.7 11.0 11.0 18.3 5.7 12.0 10.7 24.5 11.3 27.3 21.7 19.3 26.3 23.3 14.8 0.1 10.9 8.4 0.5 0.8 22.3 9.2 2.6 4.5 31.2 16.3 25.6 11.6 15.2 25.0 13.9 15.1 14.2 13.6 25.5 50.7 15.4 4.3 5.6 10.1 20.2 8.7 4.8 8.1 20.9 16.8 12.3 3.1 24.8 14.9 16.6 19.7 16.0 17.4 10.5 7.8 12.2 15.6 18.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.3 0.1 0.4 0.1 0.1 0.3 0.2 0.3 0.1 0.3 0.4 0.1 0.0 1.1 0.3 0.8 0.1 0.3 0.5 0.6 1.5 0.5 0.3 0.4 0.0 0.7 0.0 0.0 4.6 0.5 0.6 0.0 0.3 0.5 0.8 0.7 0.4 0.0 3.8 0.1 0.0 4.8 0.8 2.0 0.5 0.0 4.5 0.0 0.3 2.2 0.0 0.1 0.9 0.0 0.0 1.4 0.6 0.6 0.8 0.0 0.0 1.0 0.5 1.0 0.0 0.3 0.1 0.0 0.0 2.5 0.1 0.1 0.0 0.9 0.3 0.0 0.6 1.0 13.2 9.1 1.5 0.1 1.1 0.5 0.6 1.3 0.2 ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239027 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.2;lymphoid tissue: 3.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.4;Granulosa cells: 2.5;Spermatocytes: 2.1;Spermatogonia: 2.4;Squamous epithelial cells: 2.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.7" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.7" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Uncertain Nucleoplasm,Centrosome,Cytosol No Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Nucleoplasm, Cytosol" "HPA050492: AB_2681145" "prognostic unfavorable (1.80e-4)" "unprognostic (2.93e-1)" "unprognostic (1.95e-2)" "unprognostic (5.76e-3)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (9.23e-6)" "unprognostic (8.63e-3)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.68e-5)" "unprognostic (4.61e-2)" "unprognostic (0.00e+0)" "unprognostic (2.97e-3)" "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" 0.1 0.1 0.1 1.3 0.2 3.2 0.4 0.8 0.2 0.4 0.1 0.9 0.7 0.2 0.2 1.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.1 2.3 0.1 0.0 0.3 0.1 0.0 0.1 0.5 0.1 0.1 1.1 0.5 0.3 0.0 0.1 0.6 0.6 0.3 0.0 0.5 0.7 0.8 0.2 3.6 0.1 0.0 2.7 0.2 0.4 0.6 19.0 16.3 14.6 9.3 1.0 1.7 8.0 19.8 9.1 17.0 17.7 13.3 11.6 30.5 7.3 7.2 23.0 15.2 27.8 14.8 30.1 17.5 20.2 10.5 5.5 7.9 0.0 20.7 14.2 0.2 0.9 23.7 4.4 2.8 9.6 15.1 14.1 7.3 17.6 14.8 19.8 12.1 26.6 18.3 24.8 16.4 26.2 5.4 4.4 11.5 12.0 8.6 14.7 9.8 3.6 11.8 7.5 4.6 6.0 11.4 18.3 21.8 13.1 5.7 9.4 25.9 8.1 14.1 11.7 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.1 1.7 0.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.9 0.3 0.2 0.5 0.0 0.0 0.3 0.6 0.5 1.5 0.2 0.0 0.0 1.1 0.9 0.6 0.0 0.0 0.3 0.9 0.8 0.3 0.0 3.4 0.9 0.0 1.7 0.5 0.0 0.5 0.0 2.5 0.0 0.0 1.0 0.0 0.7 0.4 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.4 2.1 2.4 2.4 0.1 0.4 0.3 0.2 0.9 0.1 ERI1 "3'HEXO, THEX1" ENSG00000104626 "Exoribonuclease 1" Q8IV48 8 9002147-9116746 "Predicted intracellular proteins" "RNA-mediated gene silencing, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033838, HPA055548, HPA056074" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules Vesicles "CAB033838: AB_2098575, HPA055548: AB_2682845, HPA056074: AB_2683029" "unprognostic (2.49e-1)" "unprognostic (1.13e-1)" "prognostic favorable (8.05e-5)" "unprognostic (1.96e-2)" "unprognostic (2.79e-2)" "unprognostic (2.61e-3)" "unprognostic (1.08e-3)" "unprognostic (2.90e-1)" "unprognostic (5.50e-2)" "unprognostic (1.49e-1)" "unprognostic (1.25e-3)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.27e-2)" "unprognostic (3.57e-1)" "unprognostic (8.75e-2)" "unprognostic (2.36e-2)" 5.3 3.1 3.1 6.5 3.8 13.0 4.8 3.7 4.1 4.3 3.5 3.8 4.7 4.7 2.5 4.3 3.9 3.9 2.8 3.0 3.5 4.2 4.4 5.1 7.4 4.5 3.9 4.2 3.0 4.2 2.5 6.7 3.7 3.2 4.6 11.3 3.8 3.2 2.4 3.2 3.8 5.1 3.8 5.0 3.6 9.1 3.8 6.9 2.9 2.7 7.4 6.2 3.5 4.1 32.3 19.9 17.2 13.1 13.4 21.7 23.5 27.4 14.4 19.6 24.1 14.8 14.4 36.7 7.0 15.7 32.7 11.2 15.1 18.5 27.3 15.1 10.8 20.3 15.8 11.5 13.7 15.6 28.6 12.9 6.1 16.3 14.4 10.9 26.8 21.6 23.3 22.6 22.8 10.5 47.2 19.3 20.0 24.2 12.1 20.1 25.1 13.7 25.2 45.6 2.4 18.8 16.4 12.5 13.8 12.1 9.3 13.9 23.2 20.7 21.4 39.5 21.6 4.9 18.1 31.9 15.3 22.2 16.5 6.4 4.6 3.4 4.2 5.1 4.3 5.3 4.9 4.4 3.9 3.9 3.8 3.6 3.3 6.0 3.5 2.9 9.8 3.5 3.1 3.8 3.7 4.1 3.0 3.5 4.5 3.9 3.7 3.8 3.8 4.1 9.2 3.2 8.1 17.6 9.7 18.2 9.6 6.7 3.4 17.4 8.6 5.0 5.7 2.8 10.1 3.7 14.6 25.3 11.3 7.4 3.9 9.0 46.9 14.8 14.4 8.6 3.6 18.7 11.4 12.0 27.6 9.1 8.6 23.3 8.2 7.7 11.4 4.8 13.5 5.0 9.7 5.2 8.2 9.7 15.9 16.7 6.5 12.9 10.6 9.4 11.9 8.0 6.2 9.5 16.7 11.2 5.6 9.1 11.2 6.3 4.3 8.2 9.1 21.6 13.1 7.8 7.5 43.6 45.6 6.1 10.1 20.8 11.7 5.9 6.8 3.8 ERI2 "EXOD1, KIAA1504, MGC16943, ZGRF5" ENSG00000196678 "ERI1 exoribonuclease family member 2" A8K979 16 20780193-20900349 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035384, HPA035385" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "HPA035384: AB_10602316, HPA035385: AB_2674600" "unprognostic (1.25e-1)" "unprognostic (1.47e-1)" "unprognostic (2.01e-3)" "unprognostic (4.36e-2)" "unprognostic (8.64e-2)" "unprognostic (2.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (5.99e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-2)" "unprognostic (1.08e-1)" "unprognostic (2.56e-2)" "unprognostic (1.54e-1)" "unprognostic (2.45e-1)" "unprognostic (1.05e-2)" "unprognostic (9.28e-3)" 4.7 6.8 4.3 3.7 4.9 6.4 9.2 4.4 5.5 3.9 4.8 7.4 8.1 4.1 7.6 6.7 5.7 4.5 4.4 4.1 4.4 6.5 12.1 4.7 3.8 4.9 4.4 4.5 7.4 14.0 5.0 5.4 4.9 7.5 10.2 4.2 5.1 4.8 5.1 7.1 7.8 4.6 4.6 3.6 8.4 13.1 4.7 7.5 6.2 3.7 4.4 4.5 4.7 5.7 17.1 7.9 21.6 9.5 6.5 8.3 13.0 13.3 7.9 11.8 14.9 10.2 17.0 4.8 14.6 7.3 8.2 12.7 21.8 13.7 21.8 15.3 11.4 11.5 9.7 17.6 6.0 22.3 9.0 7.5 16.7 15.9 13.2 6.3 7.2 0.0 37.1 13.5 20.0 15.3 3.2 19.8 13.4 17.5 4.5 25.5 17.7 10.5 11.0 13.4 11.0 13.5 8.5 16.0 10.3 11.4 33.7 24.7 5.5 12.5 7.0 12.2 17.9 8.3 13.4 2.9 11.9 17.9 17.6 13.8 1.8 1.7 0.4 1.3 0.3 0.5 0.4 0.4 1.9 0.0 0.3 0.2 0.1 0.5 2.6 0.6 0.8 0.4 4.3 4.9 4.4 5.5 4.1 4.4 4.9 4.4 4.9 4.6 4.7 5.7 4.0 16.0 6.7 18.3 1.0 5.0 5.3 5.6 8.0 5.3 11.3 5.8 7.3 5.7 8.5 9.2 0.0 8.3 0.9 8.0 9.8 4.1 22.5 6.9 5.5 3.0 0.0 22.7 10.4 5.2 9.1 4.3 9.7 6.0 0.0 7.1 2.9 10.9 8.4 3.3 10.6 9.6 6.1 8.2 4.1 14.7 6.2 5.8 1.8 5.6 6.7 5.0 3.1 10.6 20.3 4.7 6.6 5.3 2.8 4.5 7.5 6.8 12.6 3.5 0.0 5.6 3.5 39.3 20.0 9.7 3.7 3.7 2.5 4.5 8.5 5.7 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 EXO1 "HEX1, hExoI" ENSG00000174371 "Exonuclease 1" Q9UQ84 1 241847967-241895148 "Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, Immunity, Meiosis" "DNA-binding, Endonuclease, Excision nuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 17.3;lymphoid tissue: 11.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 7.4;Extravillous trophoblasts: 16.7;Plasma cells: 11.8;Spermatocytes: 9.3;Spermatogonia: 9.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053079, HPA069738" Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA053079: AB_2682037, HPA069738: AB_2732140" "unprognostic (6.33e-3)" "unprognostic (8.54e-3)" "unprognostic (9.47e-3)" "prognostic unfavorable (8.21e-4)" "unprognostic (2.43e-1)" "unprognostic (6.34e-2)" "prognostic unfavorable (6.94e-7)" "unprognostic (1.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.40e-2)" "unprognostic (4.81e-3)" "unprognostic (9.40e-2)" "unprognostic (0.00e+0)" "unprognostic (6.72e-2)" "unprognostic (2.29e-1)" "unprognostic (1.75e-1)" "unprognostic (3.57e-1)" 0.5 0.3 0.2 3.3 0.2 17.3 1.2 0.1 0.7 0.5 0.1 3.2 2.9 0.8 0.0 2.5 0.3 0.4 0.2 0.3 0.1 0.3 0.5 0.6 5.8 0.1 0.2 0.2 0.3 0.7 0.1 3.3 0.2 0.2 3.7 0.0 0.5 0.2 0.1 1.8 2.5 1.2 0.2 1.5 1.6 5.7 0.3 11.1 0.4 0.0 6.4 1.2 0.8 0.4 41.3 26.8 43.4 28.6 2.7 6.7 36.5 53.4 17.7 46.7 50.5 33.9 22.5 44.3 25.3 12.6 25.1 40.0 55.5 22.5 54.8 69.5 48.4 41.5 28.8 17.3 1.0 59.8 29.4 1.7 1.1 46.8 12.5 5.7 14.7 43.4 84.6 57.0 37.8 19.0 65.9 33.6 60.4 49.7 26.0 46.2 40.5 47.5 9.6 25.6 48.1 60.9 34.8 27.9 19.5 20.2 25.8 36.6 5.5 44.9 39.5 42.7 72.9 41.5 59.0 71.3 15.6 48.1 54.9 0.8 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.3 0.2 0.2 0.1 0.7 0.3 0.1 0.1 0.2 0.2 0.2 0.3 0.4 0.2 0.0 0.0 0.3 0.7 0.8 0.1 0.7 0.0 0.0 0.3 0.5 2.3 0.0 0.1 0.0 0.0 5.3 0.2 1.2 0.0 0.1 9.3 0.3 0.4 0.7 0.0 7.4 1.0 0.0 16.7 0.9 1.1 0.5 0.0 4.6 0.4 0.0 3.3 0.0 2.9 0.5 0.0 0.3 0.8 2.1 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 11.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 9.3 9.8 2.7 0.1 4.0 0.8 0.8 1.9 0.3 EXO5 "C1orf176, DEM1, FLJ21144" ENSG00000164002 "Exonuclease 5" Q9H790 1 40508741-40516556 "Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 150.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028429 Supported Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA028429: AB_2092105" "unprognostic (9.44e-2)" "unprognostic (7.36e-2)" "unprognostic (3.69e-2)" "unprognostic (6.65e-2)" "unprognostic (1.66e-1)" "unprognostic (3.23e-2)" "prognostic unfavorable (9.16e-6)" "unprognostic (4.65e-2)" "unprognostic (2.24e-3)" "unprognostic (1.91e-3)" "unprognostic (4.78e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (9.95e-3)" "unprognostic (4.36e-2)" "unprognostic (4.13e-1)" "unprognostic (9.85e-3)" "unprognostic (2.53e-1)" 4.7 4.5 2.2 5.7 3.3 4.7 5.5 3.8 2.8 4.9 2.3 5.0 4.4 6.1 5.2 4.4 5.1 4.2 4.0 2.5 2.2 5.0 6.4 5.3 8.4 1.9 2.1 4.4 4.2 4.1 3.4 5.1 1.9 5.3 5.0 4.5 4.6 5.5 4.2 5.2 5.5 7.6 2.0 7.0 4.1 3.9 3.1 10.8 4.4 2.4 10.9 4.8 4.1 2.4 14.6 5.2 12.5 21.0 8.3 7.5 8.7 19.4 4.9 17.1 20.5 9.3 17.3 19.6 11.7 12.4 19.4 17.8 12.3 12.9 20.4 6.6 8.0 17.1 24.8 13.0 10.2 0.1 16.4 7.8 8.0 23.6 8.7 5.0 10.9 13.7 20.0 0.1 24.6 6.1 27.4 13.4 19.0 2.4 2.0 20.7 42.6 7.7 8.6 22.3 15.1 13.4 25.0 8.9 15.9 19.1 12.5 150.1 12.3 11.7 35.1 26.5 19.1 5.6 18.7 0.1 1.7 5.3 23.8 8.8 5.9 15.0 12.6 8.7 10.4 10.8 8.7 9.1 7.0 8.4 10.5 10.2 10.5 8.1 6.6 5.8 12.9 6.5 2.2 3.3 3.8 2.8 2.5 2.2 1.9 2.1 1.9 2.0 3.1 2.4 2.4 0.0 1.7 1.6 3.4 0.9 0.9 5.0 1.8 3.3 2.2 2.7 1.1 7.2 3.1 7.3 4.2 5.0 5.3 2.3 0.0 4.8 1.2 1.0 2.4 3.2 1.2 3.0 3.1 2.4 4.6 2.6 1.1 1.5 5.7 5.8 2.2 3.6 5.2 3.3 2.1 2.2 4.1 2.5 2.4 1.3 3.4 2.0 1.8 3.7 4.8 4.8 4.1 1.5 1.9 2.9 1.9 1.9 3.1 1.0 2.4 2.3 2.5 2.9 6.6 3.2 2.9 6.1 6.3 1.9 1.0 1.9 2.9 3.1 3.0 0.3 EXOSC2 "hRrp4p, p7, RRP4, Rrp4p" ENSG00000130713 "Exosome component 2" Q13868 9 130693721-130704894 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Deafness, Disease variant, Dwarfism, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021756, HPA021790" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA021756: AB_2670809, HPA021790: AB_1848320" "unprognostic (8.19e-2)" "unprognostic (1.93e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.22e-1)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (8.33e-3)" "unprognostic (4.82e-2)" "unprognostic (1.48e-1)" "unprognostic (8.55e-2)" "unprognostic (1.20e-3)" "unprognostic (4.73e-2)" "unprognostic (6.57e-2)" "unprognostic (3.01e-1)" "unprognostic (5.05e-2)" "unprognostic (1.41e-1)" 9.1 8.2 8.6 13.8 8.7 9.9 12.6 8.9 11.1 8.9 8.6 10.3 7.7 12.8 6.8 10.0 12.8 5.6 8.8 8.9 8.9 9.7 13.0 6.7 13.0 8.5 8.6 14.8 9.9 11.5 3.2 9.2 8.4 9.3 11.9 10.6 7.1 9.0 15.0 8.4 8.3 12.9 8.9 8.3 8.2 4.1 8.6 14.6 8.4 12.0 15.8 10.1 8.6 9.3 39.9 79.7 46.6 41.2 16.8 18.9 34.0 58.6 28.1 57.4 44.1 64.4 33.7 79.0 31.2 31.8 62.9 71.0 75.8 58.8 62.9 46.9 36.7 63.1 75.2 45.3 31.3 96.7 39.9 24.0 21.7 80.8 94.1 21.1 41.6 52.3 70.1 33.1 41.0 70.3 68.2 27.3 57.8 109.3 51.0 52.3 85.8 85.5 27.5 36.4 28.6 31.8 68.3 51.4 31.1 32.8 53.5 34.1 25.5 56.1 43.5 50.2 83.3 16.8 71.4 117.2 40.0 55.0 44.7 1.7 7.3 6.0 10.0 8.3 10.6 11.6 10.2 8.9 10.4 10.0 11.1 9.4 1.6 16.5 5.7 7.1 10.1 7.7 8.6 8.7 8.9 11.1 8.9 8.9 8.5 8.6 8.4 8.9 8.6 9.3 7.6 6.4 20.5 3.6 13.5 10.6 12.6 7.7 8.0 12.4 6.1 8.3 8.7 4.3 5.7 3.7 6.2 19.1 10.6 6.0 5.9 13.4 1.4 3.8 11.4 8.0 1.2 23.5 5.3 11.3 22.8 9.8 5.1 4.5 12.7 14.0 7.1 10.7 12.8 5.0 5.2 7.9 4.1 2.5 5.7 1.7 8.4 7.8 7.2 1.9 5.4 14.7 13.4 4.5 4.0 8.3 2.7 7.9 13.7 14.2 5.0 10.4 6.7 15.0 6.6 11.7 10.2 5.8 10.9 10.6 8.4 8.3 10.1 11.9 10.0 8.1 EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807383-148884321 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.9;lymphoid tissue: 43.0;testis: 27.8" "Cell type enhanced" "Detected in many" "Early spermatids: 109.3;Spermatocytes: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009589, HPA029131" Enhanced Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB009589: , HPA029131: AB_2672920" "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.57e-1)" "unprognostic (3.30e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "prognostic unfavorable (2.11e-6)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.58e-3)" "unprognostic (1.69e-3)" "prognostic unfavorable (8.18e-12)" "prognostic favorable (6.97e-4)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (6.67e-2)" 1.5 1.5 1.1 10.1 1.1 47.9 2.7 2.0 1.3 2.7 1.5 7.0 6.4 2.0 1.2 10.8 1.1 1.9 1.2 1.1 1.1 2.1 3.3 2.3 22.1 1.2 1.2 1.6 3.7 1.3 0.5 4.8 1.2 1.3 8.2 3.3 2.8 0.2 2.9 10.7 6.9 2.8 1.0 5.6 4.0 27.8 1.5 43.0 1.3 1.9 21.1 3.5 3.8 1.2 65.6 30.1 99.7 66.9 3.1 5.1 54.6 49.7 19.9 39.9 40.2 45.6 73.2 114.3 23.5 18.7 36.3 39.0 52.1 17.1 50.6 164.9 51.8 48.9 38.4 35.5 8.0 110.1 38.5 4.3 9.6 29.9 15.9 12.1 24.0 108.9 105.9 73.6 36.2 74.0 215.7 91.7 79.6 57.0 39.9 131.3 56.0 70.9 18.6 31.0 95.1 60.3 62.3 46.8 16.5 25.3 34.3 46.7 14.8 42.4 19.8 85.2 90.4 65.7 76.6 115.3 38.6 74.2 84.9 0.4 1.7 1.1 1.2 1.2 0.9 1.1 2.6 2.2 3.8 0.6 1.4 0.9 0.1 7.2 3.6 0.8 8.3 1.2 1.1 1.1 2.0 1.3 1.1 1.1 1.2 1.2 1.2 1.0 1.5 1.2 14.4 0.0 6.7 1.3 14.5 26.5 6.7 6.3 10.2 6.0 15.1 12.2 6.1 2.8 7.1 7.3 35.5 28.8 35.9 14.7 3.9 9.5 109.3 16.3 17.0 9.4 9.0 57.0 6.2 8.5 32.2 9.9 15.8 24.2 21.6 45.9 3.3 2.2 11.9 15.2 9.2 20.5 6.1 9.0 33.6 27.7 3.1 19.1 14.2 14.0 14.9 2.6 12.3 16.6 7.0 12.4 10.5 0.7 37.4 4.8 6.8 1.2 9.7 21.3 6.6 13.8 24.1 142.2 58.2 35.8 29.0 30.5 25.7 4.7 22.1 5.9 FAAP24 "C19orf40, FLJ46828, MGC32020" ENSG00000131944 "FA core complex associated protein 24" Q9BTP7 19 32972209-32978229 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 14.6;Spermatocytes: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041168 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA041168: AB_10960496" "unprognostic (1.18e-2)" "unprognostic (1.22e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (6.52e-2)" "unprognostic (2.73e-1)" "unprognostic (2.58e-3)" "unprognostic (3.76e-2)" "unprognostic (1.88e-2)" "unprognostic (3.98e-2)" "unprognostic (2.82e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (4.00e-7)" "unprognostic (4.37e-3)" "unprognostic (5.30e-1)" "unprognostic (2.31e-3)" "unprognostic (2.15e-1)" 1.7 1.4 0.8 2.6 0.7 3.5 1.8 1.2 1.1 1.0 1.1 1.7 1.8 1.3 2.4 1.8 1.4 2.3 0.7 0.8 0.6 1.2 1.4 1.4 3.1 1.4 0.6 2.5 0.9 0.4 0.8 1.6 1.0 4.8 2.5 0.5 1.2 1.1 0.5 2.8 2.2 1.5 0.4 2.4 1.4 6.2 0.9 2.6 1.8 0.2 3.5 1.5 1.2 2.2 6.0 15.0 5.7 9.3 3.2 6.3 4.9 7.7 8.2 14.5 18.8 10.3 9.7 7.0 11.2 3.2 11.4 4.2 11.7 5.9 11.5 19.4 5.4 15.3 5.8 7.6 1.7 5.2 7.5 3.5 3.5 9.0 5.3 2.3 5.9 11.2 8.2 7.1 11.1 6.7 11.6 7.1 2.6 8.7 6.7 10.2 5.1 3.9 2.9 3.6 5.9 4.9 8.7 9.9 6.1 6.2 6.6 13.7 3.5 14.2 6.6 6.2 7.2 5.5 12.4 9.6 10.1 11.9 9.6 15.3 5.7 8.8 3.2 6.9 3.8 6.4 4.0 4.9 3.6 6.2 3.6 5.2 13.9 7.1 7.8 6.9 5.6 3.2 0.8 0.7 1.2 1.1 0.8 0.6 1.4 0.6 1.0 0.4 0.9 2.2 1.7 3.2 1.1 0.0 3.0 0.0 3.3 0.0 1.8 1.5 3.9 3.6 0.5 2.8 1.3 3.7 2.1 11.1 6.5 1.2 1.9 1.6 7.2 4.4 3.0 2.1 1.2 7.4 0.0 8.0 14.6 3.1 0.5 6.3 1.3 7.1 3.6 0.4 8.2 5.0 0.0 2.4 0.0 5.1 0.0 12.3 3.4 3.5 0.0 0.0 7.0 0.6 2.1 0.0 0.0 4.2 2.4 3.4 2.6 3.2 3.5 1.0 0.0 1.0 0.0 2.7 2.2 22.6 8.3 2.7 0.0 5.1 2.5 5.8 2.7 2.6 FAM72B RP11-439A17.6 ENSG00000188610 "Family with sequence similarity 72 member B" Q86X60 1 121167646-121185539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.2;lymphoid tissue: 10.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7.3;Early spermatids: 11.3;Erythroid cells: 5.9;Hepatic stellate cells: 6.4;Spermatocytes: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (8.53e-2)" "unprognostic (1.97e-2)" "unprognostic (1.63e-3)" "unprognostic (1.25e-3)" "unprognostic (4.36e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-4)" "unprognostic (8.22e-5)" "unprognostic (1.30e-2)" "unprognostic (1.79e-2)" "unprognostic (1.36e-4)" "unprognostic (2.46e-2)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-2)" "unprognostic (5.30e-2)" 0.8 0.6 1.2 3.7 1.0 6.2 0.8 2.0 1.1 0.5 1.3 1.1 1.3 0.5 0.4 1.6 0.4 1.0 0.3 1.2 1.2 0.4 0.4 0.6 8.1 1.6 1.4 0.4 0.2 0.7 0.2 1.4 1.6 0.2 1.2 0.1 0.4 0.2 0.1 1.9 1.1 0.7 1.3 2.0 1.0 2.3 1.3 10.3 0.3 0.2 6.6 0.8 0.7 1.4 28.6 10.3 16.5 8.2 1.6 2.4 13.3 14.7 6.2 16.8 14.1 0.1 14.5 62.9 19.9 2.7 16.4 17.1 23.1 8.3 25.9 41.1 17.3 27.2 12.0 12.5 1.0 47.7 23.2 1.3 0.9 13.0 26.5 4.2 10.3 51.0 36.1 37.3 12.4 12.1 24.1 39.1 31.6 14.9 20.6 35.8 35.8 28.7 6.7 3.2 18.0 10.4 11.1 8.6 8.6 16.9 11.4 36.5 3.6 13.8 23.5 27.3 26.6 32.6 44.1 61.3 12.4 50.8 32.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.4 0.3 1.2 1.0 2.0 1.1 1.2 1.2 1.6 1.4 1.6 1.3 1.3 1.4 1.3 0.0 0.0 0.0 1.6 1.0 0.1 0.2 0.0 0.0 0.3 0.6 0.4 0.0 0.1 0.0 0.0 0.8 0.1 7.3 0.0 0.2 11.3 0.2 0.4 2.5 0.0 5.9 0.1 0.2 2.3 0.6 1.1 0.2 0.0 0.5 6.4 0.0 1.1 0.0 0.3 4.9 0.0 1.9 2.8 3.0 0.6 1.6 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.1 2.3 0.0 2.5 0.0 2.1 0.0 0.7 0.0 0.0 0.3 0.9 17.0 3.1 3.5 1.0 0.1 1.2 0.2 3.6 0.0 FAM72C RP5-998N21.9 ENSG00000263513 "Family with sequence similarity 72 member C" H0Y354 1 143955364-143971965 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.9;lymphoid tissue: 5.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 7.8;Extravillous trophoblasts: 4.5;Sertoli cells: 6.6;Spermatocytes: 9.4;Spermatogonia: 3.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 64.9" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (6.45e-3)" "unprognostic (2.69e-2)" "unprognostic (2.21e-1)" "unprognostic (3.98e-3)" "unprognostic (9.46e-5)" "unprognostic (1.23e-3)" "unprognostic (4.36e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.95e-1)" "unprognostic (0.00e+0)" "unprognostic (2.95e-1)" "unprognostic (4.70e-2)" "unprognostic (5.82e-2)" "unprognostic (1.47e-2)" 0.4 0.2 0.1 1.5 0.1 2.9 0.3 0.2 0.2 0.2 0.0 0.4 0.6 0.2 0.0 1.3 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.3 4.5 0.1 0.1 0.1 0.2 0.0 0.0 0.5 0.1 0.1 0.6 0.0 0.2 0.0 0.0 1.2 0.4 0.3 0.1 1.2 0.3 1.6 0.1 5.4 0.1 0.1 4.5 0.4 0.4 0.2 18.7 10.6 12.5 5.7 0.6 1.7 12.1 8.9 2.8 12.0 9.0 1.6 21.7 44.4 11.6 1.0 11.0 17.4 17.2 5.5 13.0 15.3 10.0 19.1 9.4 3.3 0.4 39.5 16.6 0.3 0.1 9.1 24.3 2.5 5.1 34.7 34.0 20.5 0.8 1.4 23.2 30.4 10.2 20.8 6.6 29.7 9.0 31.5 2.1 2.3 6.3 11.5 8.7 5.0 4.9 13.0 12.5 33.4 3.7 9.4 15.4 12.5 20.3 41.9 64.9 26.0 5.1 24.1 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.6 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 2.3 0.3 0.2 1.3 0.0 7.8 0.2 0.2 4.5 0.3 0.0 0.1 0.0 0.5 1.8 0.1 1.7 0.0 0.3 0.6 0.0 2.2 1.4 0.5 0.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 6.6 0.3 0.7 9.4 3.5 1.3 0.3 0.3 0.7 0.3 0.5 0.0 FAM72D ENSG00000215784 "Family with sequence similarity 72 member D" Q6L9T8 1 145095974-145112696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;lymphoid tissue: 6.7" "Group enriched" "Detected in some" 4 "Early spermatids: 7.3;Erythroid cells: 9.7;Extravillous trophoblasts: 5.5;Spermatocytes: 15.4;Spermatogonia: 4.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.70e-2)" "unprognostic (1.64e-1)" "unprognostic (1.73e-1)" "unprognostic (4.03e-3)" "unprognostic (1.26e-1)" "unprognostic (7.10e-3)" "unprognostic (5.88e-5)" "unprognostic (7.65e-4)" "unprognostic (6.72e-2)" "unprognostic (2.36e-2)" "unprognostic (1.22e-2)" "unprognostic (1.46e-1)" "unprognostic (0.00e+0)" "unprognostic (6.63e-2)" "unprognostic (1.72e-1)" "unprognostic (9.74e-2)" "unprognostic (6.50e-2)" 0.7 0.3 0.4 3.0 0.4 4.0 0.5 0.7 0.5 0.3 0.2 0.8 1.0 0.3 0.1 1.1 0.2 0.5 0.2 0.4 0.8 0.2 0.3 0.5 4.8 0.6 0.7 0.2 0.1 0.2 0.1 1.1 0.6 0.1 1.0 0.1 0.2 0.1 0.0 1.9 1.3 0.5 0.4 1.2 0.6 2.1 0.7 6.7 0.2 0.1 4.5 0.6 0.4 0.5 16.6 10.4 11.7 4.5 0.5 1.0 12.4 9.8 3.0 11.1 7.1 7.5 14.7 26.6 9.3 1.5 11.1 17.3 13.6 3.0 12.8 22.6 14.1 13.6 5.8 9.7 0.6 24.0 14.2 0.8 1.1 9.4 16.9 2.0 5.6 33.0 26.8 34.9 7.2 12.4 16.6 22.5 21.1 20.3 14.4 13.9 14.3 30.7 4.0 2.2 10.9 9.1 7.3 6.3 4.4 13.9 17.2 15.7 2.7 8.3 9.6 7.3 16.7 27.0 46.5 39.3 0.2 18.7 10.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.4 0.7 0.5 0.4 0.8 0.6 0.7 0.6 0.4 0.7 0.5 2.0 0.0 0.0 0.0 0.8 1.0 0.0 0.2 1.2 0.0 0.2 0.4 1.1 0.0 0.2 0.0 0.0 1.2 0.1 0.8 0.0 0.1 7.3 0.2 0.3 2.1 0.0 9.7 0.3 0.0 5.5 0.8 0.0 0.2 0.0 0.3 0.4 0.1 1.5 0.0 0.5 0.8 0.0 1.0 1.0 0.6 0.0 1.8 1.8 1.0 0.8 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.8 0.2 0.3 0.1 0.3 0.0 0.0 0.5 0.8 15.4 4.5 1.6 1.0 0.3 0.4 0.1 1.4 0.1 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.1;Spermatogonia: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 1.4 1.9 1.7 6.7 1.9 20.2 1.9 2.4 3.3 2.1 1.5 5.5 5.2 1.2 0.8 6.6 2.0 1.2 1.6 1.8 1.2 2.9 6.1 3.4 12.5 1.4 1.1 1.4 1.9 1.4 1.9 4.1 1.5 1.7 6.2 1.0 2.1 0.6 0.7 5.2 5.6 2.1 1.1 6.7 3.6 21.6 1.5 8.1 1.7 0.6 13.5 2.2 2.7 1.9 23.2 34.8 40.8 35.7 2.6 5.2 31.2 28.2 15.3 46.5 19.5 30.6 37.3 56.2 12.9 9.8 15.5 34.7 27.7 21.1 48.8 13.4 46.5 16.6 49.1 63.4 1.7 17.1 17.5 1.7 2.2 37.8 12.0 6.6 14.9 28.0 40.9 16.9 24.6 53.6 34.6 73.7 26.5 31.5 21.3 61.4 32.8 10.3 11.8 21.5 36.3 19.7 41.9 12.3 5.4 23.3 22.4 30.4 11.1 37.0 38.9 20.9 30.0 15.1 19.0 56.3 17.5 37.8 36.1 2.5 7.4 9.9 4.2 8.5 3.0 7.0 2.4 3.7 6.2 4.6 0.6 2.6 9.4 8.2 9.2 0.4 9.2 4.2 1.7 1.9 2.4 3.3 1.8 1.2 1.4 1.1 1.5 1.1 1.5 1.9 1.5 0.0 1.1 0.7 9.6 3.4 1.6 2.6 0.0 8.1 3.0 2.0 2.9 0.0 3.5 16.5 10.4 16.0 12.3 5.1 1.9 2.0 5.9 2.8 3.5 2.1 1.8 20.8 10.0 1.6 9.9 3.3 9.2 3.4 2.5 19.0 5.3 4.7 8.8 3.3 5.7 8.1 2.0 4.1 3.1 4.1 1.5 6.8 0.0 1.0 3.0 1.1 21.6 3.0 1.7 1.9 1.7 0.0 21.1 1.3 6.6 10.4 6.4 7.7 0.0 2.7 3.5 44.1 38.5 3.8 1.8 25.3 9.3 6.8 11.4 2.6 FANCB "FAAP95, FAB, FLJ34064" ENSG00000181544 "FA complementation group B" Q8NB91 X 14835961-14873069 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;brain: 3.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 12.4;Oligodendrocytes: 33.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003124 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA003124: AB_1078813" "unprognostic (3.49e-2)" "unprognostic (1.92e-3)" "unprognostic (1.16e-2)" "unprognostic (8.42e-3)" "unprognostic (7.99e-2)" "unprognostic (2.42e-2)" "unprognostic (4.05e-5)" "unprognostic (6.93e-3)" "unprognostic (1.77e-3)" "unprognostic (7.70e-3)" "unprognostic (2.76e-4)" "unprognostic (1.03e-1)" "unprognostic (1.25e-11)" "unprognostic (4.46e-2)" "unprognostic (1.92e-1)" "unprognostic (6.88e-2)" "unprognostic (5.96e-2)" 0.2 0.1 2.1 0.7 3.3 3.4 0.5 1.2 1.6 0.3 0.0 0.3 0.2 0.3 0.1 0.4 0.2 0.1 0.1 0.8 1.0 0.1 0.1 0.2 1.2 1.7 2.2 0.4 0.1 0.1 0.0 0.8 1.8 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.2 0.3 1.5 0.4 0.2 0.2 3.1 1.4 0.2 0.1 1.3 0.3 0.3 3.8 7.3 5.0 4.8 3.9 0.3 1.1 1.7 11.2 3.0 8.8 9.9 3.5 5.3 10.6 1.9 4.4 6.6 7.0 11.3 4.1 15.0 5.1 5.9 4.1 7.9 1.7 0.1 5.8 3.3 0.1 0.4 9.0 2.0 0.9 4.4 3.5 7.3 7.2 5.2 3.5 5.7 3.2 6.1 3.0 7.1 5.1 11.4 5.2 0.8 2.6 3.1 3.5 5.7 2.4 3.2 11.2 3.6 2.0 1.8 6.7 3.7 14.5 6.8 1.8 3.9 7.2 3.0 4.1 14.3 0.3 0.2 0.2 0.2 0.1 0.1 0.7 0.1 0.3 0.2 0.5 0.1 0.1 0.4 0.4 0.1 0.2 0.4 0.2 2.1 3.3 1.2 1.6 0.8 1.0 1.7 2.2 1.8 1.5 3.1 3.8 1.9 3.2 0.5 1.0 5.2 1.7 1.1 1.5 0.6 3.0 1.6 3.3 0.4 0.0 1.8 0.0 0.0 7.0 6.2 0.9 0.0 1.2 0.4 2.1 2.7 1.9 0.0 5.0 6.3 1.5 12.4 2.0 1.5 2.3 3.8 6.6 1.4 0.3 3.6 3.3 4.8 0.8 4.1 0.3 1.8 0.6 1.2 2.7 0.0 2.8 1.0 0.4 3.1 3.0 33.1 0.7 0.1 1.2 6.5 0.7 0.2 0.4 1.2 0.5 0.0 2.4 2.3 5.2 4.2 3.8 1.0 3.8 4.1 0.7 1.8 1.5 FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026414-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 120.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" 1.1 0.7 2.7 7.7 2.1 17.8 3.4 1.6 5.3 1.5 1.1 4.0 3.2 2.0 0.7 2.5 2.6 2.0 0.5 3.4 1.6 0.9 1.1 1.9 12.2 3.9 1.4 3.6 0.8 0.8 0.5 4.7 3.0 1.9 6.4 3.1 4.9 1.0 4.8 4.5 4.0 2.0 2.4 6.4 3.5 11.8 2.3 9.8 1.9 0.4 13.0 2.3 1.3 5.1 24.1 25.4 46.5 13.2 2.4 3.5 120.7 22.0 9.8 31.3 25.4 18.8 23.0 46.7 9.8 7.0 25.1 20.2 48.8 16.7 31.0 22.6 33.0 63.6 39.6 17.9 0.4 48.1 37.9 1.2 2.6 34.1 18.4 4.2 18.4 39.3 39.6 51.6 23.1 27.2 40.6 17.9 56.1 18.1 17.6 43.4 37.7 32.5 10.3 26.7 13.0 25.3 26.4 20.1 8.3 33.5 31.0 29.4 10.6 24.6 28.4 15.1 31.5 21.7 46.4 77.2 14.1 47.7 43.2 2.7 0.6 1.9 0.6 0.5 0.6 2.4 0.9 0.5 0.4 3.2 1.1 0.9 1.5 1.0 1.4 1.8 1.5 0.5 2.7 2.1 1.6 5.3 3.4 1.6 3.9 1.4 3.0 2.4 2.3 5.1 0.7 0.0 0.5 0.7 12.5 4.6 3.5 2.9 2.8 3.1 4.5 2.7 2.0 1.5 1.9 1.8 10.4 12.7 5.6 3.1 0.0 1.9 5.9 2.6 1.5 2.1 1.2 25.2 3.0 3.5 15.2 2.6 2.0 3.4 1.3 11.8 3.3 1.5 5.7 0.0 2.6 3.2 6.1 3.8 7.0 8.0 2.1 3.7 3.6 1.9 4.9 0.6 1.0 1.5 2.4 1.8 3.6 1.5 8.1 2.2 0.5 0.7 2.0 5.6 19.7 2.6 2.1 62.5 30.2 4.1 2.7 7.0 5.2 1.6 7.6 3.1 FANCG "FAG, XRCC9" ENSG00000221829 "FA complementation group G" O15287 9 35073835-35079942 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 20.6;Spermatogonia: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008105, HPA045335" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" Nucleoli "CAB008105: AB_2231542, HPA045335: AB_2679292" "unprognostic (9.41e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (8.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.14e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" 3.4 3.1 2.8 5.1 2.8 12.4 4.5 3.6 3.8 5.1 2.1 4.3 4.9 4.2 2.3 5.9 5.8 3.3 1.9 2.7 2.7 3.9 2.9 3.3 7.7 2.8 2.7 6.2 6.3 4.7 3.0 4.5 2.7 3.9 4.0 2.4 4.3 4.1 2.3 6.5 4.6 4.5 2.5 5.5 4.1 6.4 2.7 12.2 4.0 1.7 6.9 3.5 4.6 3.4 34.7 40.7 30.4 28.3 6.4 10.2 25.0 23.6 16.3 44.9 42.5 20.1 21.2 33.4 15.8 7.7 33.1 20.5 25.3 22.0 17.6 38.7 14.8 24.5 45.5 13.2 1.8 24.5 26.9 8.1 4.1 39.5 18.2 8.0 23.8 40.7 15.7 44.3 23.5 31.5 43.2 34.5 32.5 26.4 30.1 43.8 35.2 23.1 10.9 14.6 14.4 26.1 15.7 22.3 8.3 13.4 28.4 17.2 13.4 21.0 42.8 28.3 33.1 12.4 24.0 20.6 19.2 18.5 30.1 10.5 0.7 6.7 6.1 2.2 5.3 5.6 4.8 4.6 1.9 5.4 3.6 3.8 1.1 7.8 2.0 4.2 8.2 3.1 2.8 2.8 3.6 3.8 2.7 2.7 2.8 2.7 2.7 2.5 2.7 3.4 3.2 3.2 4.6 6.8 4.9 4.5 6.1 3.9 10.2 4.7 5.9 5.0 1.5 2.8 3.3 3.7 4.2 15.0 4.1 3.0 3.9 4.9 0.4 2.3 3.8 4.4 1.8 11.6 3.0 2.3 20.6 5.1 1.5 3.6 14.0 10.3 4.2 1.1 7.7 5.0 3.3 4.1 2.0 1.3 4.7 0.6 3.4 2.3 3.6 1.0 2.8 4.0 3.1 0.5 4.1 1.9 2.4 4.1 14.1 4.4 3.5 2.3 1.3 3.1 0.0 3.0 3.9 14.7 20.7 8.5 2.6 6.6 4.9 2.8 6.7 5.2 FANCI "FLJ10719, KIAA1794" ENSG00000140525 "FA complementation group I" Q9NVI1 15 89243945-89317261 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.4;lymphoid tissue: 44.2;testis: 32.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.6;Spermatocytes: 69.5;Spermatogonia: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039972, HPA040379" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039972: AB_10673265, HPA040379: AB_2676951" "unprognostic (6.88e-2)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.82e-3)" "unprognostic (1.15e-2)" "unprognostic (4.59e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.71e-13)" "unprognostic (2.40e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" 3.2 2.1 1.6 13.0 1.3 31.4 6.0 3.8 2.5 3.3 0.0 10.5 6.0 4.7 1.1 8.1 3.4 3.0 1.7 1.7 0.7 1.7 2.9 3.4 23.9 1.2 0.9 3.8 3.0 3.0 0.6 11.3 1.7 3.6 12.4 5.4 2.8 2.0 0.8 8.0 7.3 6.9 0.6 6.0 6.7 32.6 1.3 44.2 2.0 0.8 26.6 5.4 3.7 1.7 108.2 122.4 127.8 86.1 10.8 16.0 78.5 101.4 58.3 123.6 150.5 96.8 95.4 198.8 53.4 33.8 79.3 143.9 196.8 69.0 116.2 127.8 123.5 197.2 176.7 45.8 1.7 146.0 96.3 8.6 6.8 87.1 44.4 17.6 51.7 120.2 139.2 142.3 83.5 61.5 150.9 49.6 101.1 70.3 44.5 130.6 187.1 84.6 28.5 196.8 93.9 80.8 105.2 73.3 46.7 85.7 81.2 64.8 35.4 103.2 103.8 94.9 155.8 93.3 209.5 151.9 38.5 125.7 104.7 23.4 2.3 3.0 4.7 3.0 2.8 3.5 4.7 6.5 2.2 3.6 3.3 5.6 3.1 5.1 4.3 4.1 11.8 3.1 1.6 1.3 3.8 2.5 1.7 0.7 1.2 0.9 1.7 0.6 1.3 1.7 2.6 3.2 1.5 3.6 3.8 4.2 2.6 4.0 0.6 2.4 2.9 2.7 3.9 0.0 3.3 1.8 0.0 17.0 3.9 4.2 0.0 2.0 7.9 5.0 3.7 3.0 1.2 48.6 7.0 2.9 18.3 3.9 5.6 4.5 2.5 14.9 6.8 0.8 8.1 1.7 5.8 5.9 0.0 3.0 3.8 7.9 3.4 4.8 1.8 1.9 3.3 11.6 1.0 9.0 6.9 2.5 1.2 1.5 13.9 2.0 1.3 1.0 6.3 1.9 6.6 3.6 4.0 69.5 60.2 9.2 2.4 12.4 8.1 2.5 9.1 2.8 FBXO5 "EMI1, FBX5, Fbxo31" ENSG00000112029 "F-box protein 5" Q9UKT4 6 152970519-152983579 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.1;lymphoid tissue: 27.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.0;Extravillous trophoblasts: 30.5;Spermatocytes: 32.3;Spermatogonia: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008106, HPA029048" Approved Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008106: AB_828450, HPA029048: AB_10602132" "unprognostic (1.22e-2)" "unprognostic (7.21e-2)" "unprognostic (4.61e-3)" "unprognostic (1.24e-2)" "unprognostic (5.92e-2)" "unprognostic (2.94e-2)" "unprognostic (2.43e-8)" "unprognostic (2.46e-2)" "unprognostic (1.55e-2)" "unprognostic (7.32e-2)" "unprognostic (2.89e-1)" "unprognostic (5.86e-2)" "unprognostic (1.25e-9)" "prognostic favorable (8.65e-4)" "unprognostic (1.20e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-1)" 3.1 3.1 1.5 7.3 1.6 44.1 4.5 2.6 2.1 4.0 1.9 5.0 4.6 5.3 4.5 3.7 3.0 2.6 1.8 1.4 1.7 3.1 4.4 3.4 14.9 1.6 1.6 4.1 3.0 2.3 2.1 6.3 1.7 3.0 5.1 3.3 2.7 2.9 0.9 4.3 4.3 5.0 1.6 5.5 4.6 3.9 1.8 27.3 4.4 2.6 14.6 4.0 3.0 2.0 33.7 17.2 70.8 48.1 5.3 10.8 22.6 79.9 35.5 58.7 65.6 35.6 19.8 81.6 23.9 21.3 39.7 31.4 56.4 26.7 70.0 44.2 50.6 82.3 24.1 38.7 10.2 74.4 48.6 7.7 4.9 39.8 30.9 14.3 27.3 42.3 88.2 74.5 53.9 25.7 85.2 47.6 41.5 25.8 25.0 71.0 56.8 52.8 20.8 18.0 46.1 47.9 56.6 30.2 15.6 24.7 21.8 68.7 20.6 43.9 57.4 51.1 94.8 24.9 29.5 120.4 31.9 54.3 54.2 0.0 1.9 0.0 2.8 2.5 4.0 5.1 4.7 5.2 3.7 5.0 4.6 4.8 0.0 7.1 3.2 4.3 6.6 2.5 1.5 1.6 2.6 2.1 1.4 1.7 1.6 1.6 1.7 1.6 1.8 2.0 6.0 0.0 1.1 1.3 9.8 9.9 3.7 4.0 7.4 3.2 5.7 5.2 1.8 2.8 3.9 1.8 6.2 15.2 13.5 2.6 3.9 3.0 0.4 2.3 10.5 5.7 4.8 36.0 1.0 1.6 30.5 9.1 7.7 4.0 2.5 16.6 5.0 1.9 7.9 1.7 0.9 6.1 2.0 3.2 6.1 0.1 4.4 5.3 1.8 1.9 4.2 4.1 9.2 1.5 2.1 1.5 0.5 6.0 24.7 3.6 1.5 3.6 1.9 3.6 13.1 8.6 8.9 32.3 26.1 10.2 5.3 5.9 7.9 8.0 6.3 2.0 FEN1 "FEN-1, MF1, RAD2" ENSG00000168496 "Flap structure-specific endonuclease 1" P39748 11 61792911-61797238 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 87.5;Extravillous trophoblasts: 70.9;Spermatocytes: 61.0;Spermatogonia: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002262, HPA006748" Enhanced Enhanced Nucleoplasm,Nucleoli NA Yes 160000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002262: AB_563729, HPA006748: AB_1848494" "unprognostic (1.82e-1)" "unprognostic (2.71e-2)" "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (1.26e-1)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.50e-2)" "unprognostic (9.82e-2)" "prognostic favorable (7.85e-4)" "unprognostic (2.82e-3)" "unprognostic (5.86e-2)" "prognostic unfavorable (5.73e-6)" "prognostic favorable (9.46e-4)" "unprognostic (1.10e-1)" "unprognostic (4.49e-3)" "unprognostic (4.04e-2)" 5.9 10.4 7.8 21.3 7.8 39.5 10.2 10.9 9.9 6.2 9.6 15.5 11.2 6.3 7.1 14.2 5.7 4.3 6.6 8.0 7.7 5.8 9.9 5.6 34.0 10.0 8.3 3.9 6.8 5.6 8.3 12.9 10.7 6.2 16.1 17.4 6.1 5.9 13.1 9.6 11.4 8.9 6.8 12.8 8.4 19.1 9.1 46.0 4.8 9.6 37.4 8.1 4.9 8.1 154.6 139.7 149.3 81.3 14.9 18.0 94.9 133.3 76.1 160.9 181.4 123.4 112.8 222.6 100.3 57.3 150.5 158.3 214.3 117.7 163.3 117.8 117.6 117.6 187.7 127.3 11.0 184.7 115.4 12.7 15.8 148.1 39.0 23.3 63.1 122.1 181.3 155.1 136.0 195.4 259.7 165.4 165.3 120.3 134.7 173.8 173.7 228.9 64.4 144.7 170.0 140.7 89.6 115.0 79.1 70.1 167.4 127.1 43.2 141.5 178.1 182.3 134.6 120.4 204.3 228.9 98.4 121.9 124.6 24.7 6.7 14.2 16.2 12.9 16.8 14.4 12.3 15.1 8.0 14.8 14.0 13.8 2.7 20.0 12.9 24.5 25.2 10.3 7.8 7.8 10.9 9.9 8.0 7.7 10.0 8.3 10.7 6.8 9.1 8.1 2.7 0.0 2.2 0.3 14.0 10.3 5.2 18.2 7.4 23.8 7.4 7.4 5.8 5.7 7.7 0.0 12.5 53.0 15.9 6.7 7.9 17.3 21.7 4.2 5.5 5.5 4.8 87.5 2.0 12.2 70.9 8.6 7.1 6.3 0.0 18.6 1.1 7.2 25.7 15.2 2.4 8.0 18.3 5.4 6.8 14.4 5.6 6.2 5.4 0.0 12.4 31.3 13.4 1.5 3.1 12.2 9.4 7.2 45.3 6.5 3.7 5.7 6.4 23.3 0.0 6.8 12.2 61.0 62.1 11.3 6.1 30.9 11.0 9.0 22.0 5.2 FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 32.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Erythroid cells: 18.7;Extravillous trophoblasts: 18.2;Late spermatids: 25.5;Plasma cells: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (3.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.95e-6)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.01e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (6.09e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" 1.9 1.1 0.4 9.4 0.5 25.0 1.8 0.8 0.8 1.7 0.2 10.5 9.7 1.7 0.2 11.1 0.8 1.5 0.5 0.8 0.3 0.7 1.2 1.8 11.3 0.4 0.9 0.3 0.4 0.4 0.1 6.1 0.6 0.7 12.5 1.1 1.9 0.8 0.6 6.4 8.8 7.5 0.1 3.1 5.2 21.4 1.0 32.2 0.9 0.3 15.2 3.0 3.2 0.6 133.0 129.5 101.3 92.2 14.2 19.0 129.2 84.0 80.4 165.2 147.2 166.9 114.8 84.5 17.7 119.8 188.5 100.2 153.1 76.1 160.0 159.8 80.3 94.7 121.6 71.6 2.0 79.2 75.0 9.9 8.3 154.4 106.1 39.1 117.8 96.8 55.6 184.9 130.5 122.6 108.3 36.8 225.6 136.1 95.4 77.3 149.8 44.1 38.1 82.7 56.3 89.1 106.7 90.4 46.6 189.4 87.1 87.8 48.0 134.3 200.5 160.4 300.4 24.7 44.3 122.1 63.1 74.3 147.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.8 0.8 0.8 0.3 0.4 0.9 0.6 0.1 1.0 0.6 0.1 0.0 1.3 0.7 2.4 2.9 1.3 1.0 1.2 2.0 1.7 1.3 0.5 1.5 0.8 1.8 4.2 7.1 0.8 6.6 1.9 0.2 22.4 1.2 2.1 2.5 0.0 18.7 1.1 0.0 18.2 3.2 10.2 2.4 0.0 15.4 3.6 0.8 9.1 5.0 0.6 7.5 2.0 4.2 1.2 25.5 0.9 2.4 0.0 0.0 1.1 0.6 1.0 0.5 1.0 0.3 0.3 0.7 19.9 1.0 1.4 0.4 0.2 4.0 0.0 1.2 3.0 15.0 9.9 10.2 1.4 1.9 3.3 0.9 12.9 1.9 FOXRED1 H17 ENSG00000110074 "FAD dependent oxidoreductase domain containing 1" Q96CU9 11 126269055-126278131 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039620, HPA046192" Uncertain Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA039620: AB_2676602, HPA046192: AB_2679580" "prognostic unfavorable (7.36e-4)" "unprognostic (4.62e-2)" "unprognostic (2.71e-1)" "unprognostic (3.47e-3)" "unprognostic (1.76e-1)" "unprognostic (1.84e-1)" "unprognostic (9.59e-2)" "unprognostic (1.43e-1)" "unprognostic (8.14e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.01e-6)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" 8.1 13.8 13.6 5.9 14.6 12.1 7.6 15.3 16.6 5.8 17.1 12.0 10.4 6.7 6.4 9.2 7.5 5.6 21.2 15.0 14.7 14.7 37.4 5.3 10.4 15.3 14.3 4.8 7.8 9.7 8.1 7.1 15.3 6.9 12.9 3.7 7.3 6.8 17.8 7.5 8.6 7.9 14.7 11.1 10.9 8.7 15.8 11.5 6.1 29.4 10.6 7.1 6.0 14.8 23.5 26.6 19.5 24.3 14.2 6.8 26.1 11.6 14.9 22.1 22.1 40.0 24.1 38.2 32.3 9.8 28.7 38.5 51.7 31.5 13.8 20.4 14.3 79.7 16.7 48.2 18.8 19.7 16.4 6.3 12.1 14.9 26.5 6.0 24.7 40.2 46.6 20.6 18.7 32.7 23.1 35.3 16.0 61.8 45.2 37.0 34.1 45.2 20.5 11.9 25.0 21.5 23.8 35.7 13.1 12.2 85.9 33.4 9.0 13.1 10.7 23.8 19.4 12.2 19.0 31.9 16.2 66.5 18.7 1.6 10.1 5.9 6.7 13.4 7.0 7.1 5.3 8.9 12.1 6.2 7.4 6.7 2.0 9.9 9.9 16.8 7.6 8.1 13.6 14.6 15.3 16.6 15.0 14.7 15.3 14.3 15.3 14.7 15.8 14.8 6.1 9.6 11.5 19.6 13.5 3.6 6.2 14.9 8.0 24.8 7.3 7.0 21.7 10.0 10.7 3.7 27.1 27.7 12.2 12.6 7.9 13.6 4.2 7.4 8.7 7.6 13.1 14.9 24.7 13.8 24.1 9.8 17.9 7.8 9.5 17.8 10.0 28.2 20.4 13.5 27.1 12.6 8.2 7.1 5.1 7.2 5.6 8.0 8.8 4.7 7.1 18.6 9.2 14.1 16.1 10.7 5.9 11.3 24.4 4.6 8.9 21.0 6.7 32.2 6.6 8.9 9.6 24.5 24.0 11.0 5.7 21.1 8.9 25.0 14.9 4.8 GEMIN2 SIP1 ENSG00000092208 "Gem nuclear organelle associated protein 2" O14893 14 39114223-39136973 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 45.8;Late spermatids: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015426, HPA046570, HPA057114" Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" Nucleoli "CAB015426: AB_629517, HPA046570: AB_2679703, HPA057114: AB_2683340" "unprognostic (4.53e-1)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "unprognostic (5.07e-3)" "unprognostic (1.04e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.88e-6)" "unprognostic (8.62e-3)" "unprognostic (3.05e-2)" "unprognostic (1.99e-3)" "unprognostic (3.08e-1)" "unprognostic (3.03e-1)" "unprognostic (4.53e-3)" "unprognostic (1.52e-1)" "unprognostic (1.58e-1)" "unprognostic (3.95e-1)" "unprognostic (6.78e-2)" 6.1 4.3 6.1 4.5 6.3 10.3 7.9 10.2 7.9 5.9 4.6 6.0 6.7 5.4 7.2 5.7 5.9 4.2 7.7 5.7 3.9 6.1 5.6 4.8 8.8 3.6 2.6 5.9 4.7 3.7 4.6 5.6 3.6 4.8 6.1 4.7 4.3 4.5 12.1 6.3 4.7 7.7 1.1 5.2 5.1 8.3 3.4 9.1 5.5 7.9 7.8 6.2 5.5 6.2 23.6 34.5 33.3 23.7 11.3 12.6 17.0 11.5 9.0 30.3 30.0 30.7 27.9 36.0 23.4 9.8 11.0 17.5 45.6 18.7 31.5 17.6 26.7 21.5 18.1 76.8 23.9 32.6 12.8 7.3 17.6 18.8 27.5 8.7 26.6 31.4 25.2 25.6 17.3 48.9 36.3 31.2 23.6 29.7 38.3 32.8 36.4 22.6 17.5 15.6 32.2 6.2 24.5 17.7 12.4 18.4 41.5 14.0 11.2 12.7 20.0 13.3 18.6 26.8 44.2 54.1 6.6 34.0 19.6 10.8 12.0 9.9 13.5 13.1 9.8 15.3 12.3 13.5 16.2 15.8 13.5 14.4 3.1 11.9 11.5 16.1 11.8 9.2 6.1 6.3 10.2 7.9 5.7 3.9 3.6 2.6 3.6 1.1 3.4 6.2 11.6 6.4 3.7 4.9 10.3 8.5 8.1 20.9 8.0 5.9 7.3 12.1 6.0 5.7 11.4 5.5 10.4 12.9 7.0 2.2 11.7 10.8 45.8 11.2 11.3 10.6 3.6 17.2 7.4 6.4 18.9 12.5 2.6 7.5 5.7 11.7 9.7 6.6 11.4 5.0 6.2 7.1 14.2 10.6 7.3 41.1 9.0 6.3 7.2 4.7 9.4 8.1 9.2 4.0 7.4 6.9 2.5 9.8 9.4 8.0 3.1 14.7 15.5 6.9 6.6 8.3 8.1 25.9 15.4 11.3 8.0 3.8 9.1 11.6 9.3 4.8 GEN1 "FLJ40869, Gen" ENSG00000178295 "GEN1 Holliday junction 5' flap endonuclease" Q17RS7 2 17753858-17788946 "Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA020078, HPA021141" Enhanced Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA020078: AB_2670352, HPA021141: AB_2670599" "unprognostic (2.25e-1)" "unprognostic (2.33e-1)" "unprognostic (1.52e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (8.64e-2)" "unprognostic (1.67e-3)" "unprognostic (7.90e-4)" "unprognostic (4.53e-2)" "unprognostic (1.70e-3)" "unprognostic (8.60e-3)" "unprognostic (8.04e-2)" "unprognostic (6.99e-2)" "unprognostic (1.89e-12)" "unprognostic (3.97e-3)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (1.49e-3)" 1.6 1.8 1.1 4.8 1.0 15.1 3.2 0.7 1.2 2.3 15.4 5.2 3.2 1.8 9.3 5.6 1.4 4.4 2.3 1.5 1.7 1.7 8.6 2.0 10.8 2.1 2.4 0.9 2.2 1.1 3.0 3.9 1.8 2.7 6.9 2.5 5.6 2.7 1.7 7.5 4.5 1.4 1.7 5.1 3.0 8.5 1.6 5.4 1.9 1.5 11.8 1.5 3.7 1.8 29.4 15.0 14.0 9.9 3.2 4.1 23.9 21.3 6.7 9.9 9.6 19.6 13.0 27.4 8.2 7.3 10.4 18.4 16.4 12.8 13.7 21.4 9.1 15.7 16.3 9.5 1.9 20.2 17.0 3.1 4.7 16.8 7.7 3.0 8.0 13.7 21.0 19.6 16.4 14.1 15.2 16.4 9.5 9.4 6.8 17.7 36.3 10.9 5.6 19.6 15.3 20.8 11.5 14.3 7.5 9.5 9.8 10.6 10.7 22.4 9.8 12.2 21.8 13.1 26.0 45.1 9.6 18.3 16.0 0.1 0.4 0.3 0.3 0.3 0.2 1.7 0.3 0.6 0.6 0.7 0.4 0.4 0.1 0.4 0.4 0.6 0.5 0.3 1.1 1.0 0.7 1.2 1.5 1.7 2.1 2.4 1.8 1.7 1.6 1.8 3.6 6.4 3.6 12.1 16.9 2.8 2.7 5.2 5.7 5.7 4.5 3.0 4.4 1.5 8.1 3.7 12.5 4.4 6.9 9.3 0.0 2.1 4.6 4.9 8.5 4.0 1.8 15.3 14.1 2.3 4.8 4.2 17.3 6.6 1.3 14.5 2.2 5.4 3.8 3.3 13.0 7.3 0.0 3.1 1.0 3.7 1.8 4.0 1.8 6.5 2.9 3.8 1.0 12.5 11.0 2.9 4.0 0.7 11.2 3.2 5.3 2.5 5.0 3.6 6.6 15.0 5.3 14.2 11.4 8.1 1.8 3.3 3.7 8.0 7.2 2.9 GINS1 "KIAA0186, PSF1" ENSG00000101003 "GINS complex subunit 1" Q14691 20 25407673-25452628 "Disease related genes, Predicted intracellular proteins" "DNA replication" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.3;testis: 9.0" "Cell type enhanced" "Detected in many" "Early spermatids: 60.2;Erythroid cells: 14.7;Extravillous trophoblasts: 17.9;Late spermatids: 21.9;Spermatocytes: 14.2;Spermatogonia: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051185 Uncertain Approved Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051185: AB_2681378" "unprognostic (6.10e-3)" "unprognostic (2.58e-1)" "unprognostic (5.37e-3)" "unprognostic (1.74e-3)" "unprognostic (2.00e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.61e-7)" "unprognostic (5.86e-3)" "unprognostic (1.42e-2)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.42e-11)" "unprognostic (5.24e-2)" "unprognostic (1.03e-1)" "unprognostic (4.60e-2)" "unprognostic (2.55e-1)" 0.7 0.6 0.9 3.2 0.8 3.4 1.6 1.8 1.0 1.0 0.4 3.2 3.0 1.4 0.7 4.3 0.8 0.8 0.5 0.8 0.5 1.1 1.2 0.5 5.3 0.4 0.5 0.9 0.5 0.6 0.2 2.9 0.6 0.8 3.9 0.8 0.8 0.4 0.5 3.7 2.9 2.0 0.3 1.5 2.0 9.0 0.6 7.3 0.6 0.0 5.9 1.3 1.5 0.9 43.6 38.8 46.5 30.4 2.6 3.5 46.7 18.9 9.1 35.5 37.2 33.7 42.1 53.3 21.0 7.9 26.4 49.0 40.9 34.4 40.7 14.3 14.2 36.7 13.8 41.3 0.9 48.5 16.2 1.7 2.0 33.8 6.9 4.7 19.1 30.1 36.1 33.9 21.2 47.0 75.1 36.0 31.8 30.0 20.0 53.1 53.6 35.7 13.6 28.8 19.4 20.3 19.3 45.3 16.7 26.0 42.9 24.2 8.7 27.7 29.9 18.2 35.1 13.6 41.1 42.0 7.4 46.8 32.0 0.2 0.2 0.1 0.3 0.2 0.1 0.5 0.2 0.1 0.5 0.3 0.1 0.3 0.2 0.4 0.2 0.5 0.8 0.2 0.9 0.8 1.8 1.0 0.8 0.5 0.4 0.5 0.6 0.3 0.6 0.9 0.2 0.0 0.6 1.3 1.5 3.2 1.0 1.5 1.8 1.8 1.1 1.3 0.4 0.0 1.6 1.8 0.0 8.2 0.2 1.9 0.0 1.1 60.2 0.5 1.3 1.1 1.2 14.7 6.4 0.7 17.9 2.0 3.6 1.3 1.3 6.8 0.7 0.7 5.9 0.0 3.7 2.5 0.0 1.6 0.8 21.9 0.6 1.2 0.0 1.0 0.0 1.3 0.0 4.0 1.6 0.4 0.6 1.2 8.9 0.6 0.4 2.1 1.7 0.2 0.0 0.5 1.4 14.2 19.7 5.4 1.4 2.5 0.8 2.0 5.5 0.8 GINS2 "Pfs2, PSF2" ENSG00000131153 "GINS complex subunit 2" Q9Y248 16 85676198-85690073 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 163.5;Spermatogonia: 148.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 271.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA057285 Uncertain Approved Nucleoplasm No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA057285: AB_2683398" "unprognostic (3.22e-2)" "unprognostic (1.13e-3)" "unprognostic (2.04e-3)" "unprognostic (2.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.30e-1)" "unprognostic (2.45e-3)" "unprognostic (2.58e-2)" "unprognostic (1.67e-2)" "unprognostic (2.52e-3)" "unprognostic (2.19e-2)" "unprognostic (5.82e-3)" "unprognostic (5.70e-3)" "unprognostic (4.54e-2)" "unprognostic (6.30e-2)" "unprognostic (5.44e-3)" "unprognostic (1.60e-1)" 1.0 0.9 3.0 5.4 2.8 14.7 3.7 3.0 3.7 1.7 2.2 6.4 4.6 1.6 1.3 4.7 1.1 0.4 0.6 4.5 2.2 0.7 3.0 0.8 9.0 2.3 2.4 1.4 0.9 2.6 0.8 3.0 2.3 1.5 7.0 11.1 1.3 0.8 2.7 3.2 5.3 1.6 2.3 3.0 2.2 9.6 2.3 10.2 1.8 1.0 11.0 1.4 2.1 2.6 50.7 36.2 69.0 28.9 2.0 6.7 18.3 33.8 13.7 49.8 30.5 48.2 32.9 60.0 18.1 12.0 26.0 38.0 73.7 28.1 47.9 20.8 63.9 29.2 25.7 54.6 0.3 20.6 15.6 1.8 3.4 30.0 11.5 6.1 21.6 47.5 82.4 13.8 28.9 107.1 72.7 77.8 38.8 45.0 27.3 100.7 41.5 33.1 16.4 20.9 94.2 30.0 49.4 10.0 10.0 27.3 100.0 28.2 12.8 32.1 42.5 30.6 39.5 25.6 48.3 271.9 18.7 43.4 37.2 0.7 0.2 1.1 1.0 1.0 0.1 1.0 3.3 2.3 1.3 0.7 1.6 1.1 0.9 3.2 2.8 0.8 8.5 1.7 3.0 2.8 3.0 3.7 4.5 2.2 2.3 2.4 2.3 2.3 2.3 2.6 0.6 3.2 0.0 0.7 8.5 9.2 7.4 9.5 4.0 20.3 13.1 18.5 1.0 0.0 3.8 3.7 2.1 35.3 3.1 11.9 3.9 8.2 9.8 1.5 3.3 2.4 3.0 43.3 0.5 1.5 31.8 7.2 5.6 2.7 1.3 21.6 0.0 2.1 23.8 8.4 0.4 14.9 4.1 1.3 6.6 29.4 1.2 3.3 0.0 0.0 1.1 5.6 0.0 1.0 0.6 2.0 4.5 1.9 43.1 2.6 2.4 0.7 1.7 7.5 19.7 4.2 7.9 163.5 148.4 13.8 3.8 12.7 4.2 2.2 33.6 7.4 GINS3 "FLJ13912, PSF3" ENSG00000181938 "GINS complex subunit 3" Q9BRX5 16 58295080-58406147 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-698: 146.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041216, HPA048209" Uncertain Enhanced Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA041216: AB_10794989, HPA048209: AB_2680314" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-3)" "unprognostic (6.34e-2)" "unprognostic (4.70e-2)" "unprognostic (2.82e-1)" "unprognostic (1.75e-4)" "unprognostic (7.76e-2)" "unprognostic (1.76e-3)" "unprognostic (7.19e-2)" "unprognostic (4.50e-2)" "unprognostic (2.67e-3)" "unprognostic (1.14e-7)" "unprognostic (9.76e-3)" "unprognostic (5.34e-2)" "unprognostic (8.23e-2)" "unprognostic (1.07e-2)" 4.3 7.4 2.0 4.2 4.2 8.4 3.7 3.7 2.6 3.7 2.2 5.8 3.2 2.8 3.7 9.1 2.4 1.5 6.2 2.4 2.5 2.5 2.6 2.1 7.8 3.0 3.5 1.3 1.7 3.7 2.0 3.7 2.7 2.2 4.2 1.8 3.4 4.6 1.8 4.5 2.8 3.8 2.8 5.4 2.6 6.8 3.2 8.8 1.9 4.9 8.0 3.0 6.7 2.7 20.2 22.4 26.5 14.3 2.9 3.7 13.3 22.4 9.8 35.4 26.8 16.9 20.2 35.0 17.5 7.6 26.3 18.7 24.5 18.8 39.6 19.5 30.4 20.4 12.0 20.5 1.6 26.1 33.7 4.2 3.5 18.4 6.3 7.9 24.4 28.9 33.5 14.4 15.0 20.9 48.1 24.2 24.5 17.2 45.3 82.6 29.4 44.4 12.8 12.6 30.3 20.1 37.3 24.3 12.8 10.6 12.9 21.4 10.4 23.5 27.8 14.2 28.4 14.3 20.2 146.3 16.2 26.1 29.3 0.1 1.8 0.1 1.9 1.6 1.5 2.5 1.6 2.9 4.1 4.4 1.5 2.5 0.4 4.1 1.0 8.2 2.4 1.5 2.0 4.2 3.7 2.6 2.4 2.5 3.0 3.5 2.7 2.8 3.2 2.7 3.9 0.0 2.6 9.1 3.2 1.8 4.9 2.7 4.0 1.5 2.0 1.7 4.1 0.0 1.4 0.0 2.1 9.1 4.5 1.6 0.0 3.7 20.7 1.8 2.1 4.3 0.0 12.4 0.6 2.0 7.6 2.5 1.5 7.9 1.3 6.9 3.6 0.8 2.8 5.0 0.2 0.9 0.0 1.6 1.1 9.2 1.5 1.9 1.8 2.8 2.6 1.8 2.1 5.0 1.2 1.9 0.3 1.2 6.2 1.7 0.2 0.5 1.1 1.8 6.6 1.6 3.0 4.6 8.7 13.0 2.4 3.1 2.4 3.2 2.8 4.9 GINS4 "MGC14799, SLD5" ENSG00000147536 "GINS complex subunit 4" Q9BRT9 8 41529218-41545030 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024663, HPA026580" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Centrosome "HPA024663: AB_1857224, HPA026580: AB_1857225" "unprognostic (7.74e-2)" "unprognostic (3.72e-2)" "unprognostic (2.25e-3)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.70e-1)" "unprognostic (4.01e-2)" "unprognostic (1.71e-3)" "unprognostic (8.01e-3)" "unprognostic (4.03e-3)" "unprognostic (1.50e-2)" "unprognostic (4.34e-4)" "unprognostic (1.79e-1)" "unprognostic (3.67e-5)" "unprognostic (2.40e-3)" "unprognostic (1.39e-1)" "unprognostic (4.11e-1)" "unprognostic (3.22e-1)" 0.8 0.8 0.9 4.0 1.2 5.9 1.8 1.5 1.1 0.9 0.9 2.1 1.6 1.4 0.7 1.7 0.8 1.5 0.7 0.9 0.9 0.6 1.4 0.7 5.1 1.4 1.0 1.1 0.9 0.6 0.2 2.6 1.2 0.7 3.0 0.8 0.8 0.5 0.5 2.1 1.7 1.5 0.5 1.7 1.3 2.9 1.0 6.2 1.3 0.1 6.0 1.2 0.8 2.3 20.3 28.3 39.4 17.9 2.4 3.1 16.4 28.1 16.9 28.8 33.6 26.4 17.3 28.1 11.2 14.3 21.6 15.0 32.1 23.4 41.9 10.4 17.8 40.8 20.6 17.9 0.6 8.9 20.2 1.7 1.1 47.2 10.4 6.6 14.4 33.0 20.3 9.0 20.4 13.8 37.6 10.1 22.0 21.5 15.4 34.4 36.8 11.8 10.3 19.1 12.2 9.5 20.3 8.8 8.1 19.9 22.8 9.9 10.0 19.3 28.9 36.1 28.8 10.6 16.4 33.0 13.8 20.9 48.3 1.5 0.7 0.3 1.5 0.7 0.9 1.2 2.5 1.0 0.3 2.8 1.5 1.0 1.9 1.4 0.3 2.9 3.7 1.0 0.9 1.2 1.5 1.1 0.9 0.9 1.4 1.0 1.2 0.5 1.0 2.3 1.3 0.0 1.1 0.7 6.4 2.8 2.8 2.3 1.2 4.0 2.1 4.3 0.8 0.0 1.3 9.2 2.1 9.1 5.6 3.7 0.0 1.8 0.9 2.0 2.3 1.9 3.5 9.9 0.2 1.8 12.4 3.5 4.1 3.7 1.3 17.5 1.1 0.5 4.8 0.0 0.7 4.0 4.1 1.8 9.4 0.6 1.2 5.7 0.0 0.0 9.6 1.7 3.1 0.0 2.5 2.1 0.3 2.2 9.2 1.2 0.5 0.9 0.3 2.5 0.0 3.6 5.9 9.6 11.8 2.5 1.1 5.9 6.9 9.0 6.0 1.6 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 5.3;testis: 7.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Extravillous trophoblasts: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA027422, HPA030698" Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027422: AB_10601812, HPA030698: AB_2673575" "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" 0.2 0.1 0.0 1.8 0.2 6.0 0.4 0.0 0.1 0.2 0.2 1.1 1.5 0.2 0.1 1.3 0.3 0.2 0.1 0.0 0.0 0.1 0.1 1.4 4.2 0.1 0.1 0.1 0.2 0.0 0.0 0.6 0.1 0.3 1.0 0.0 0.4 0.0 0.6 0.7 1.8 0.4 0.0 1.7 0.9 7.3 0.2 5.3 0.3 0.1 5.1 0.3 0.5 0.2 11.3 12.2 11.1 12.5 0.7 1.4 9.3 10.2 7.8 19.7 19.3 9.6 4.6 27.7 5.7 5.7 7.9 18.0 20.1 9.9 18.7 0.1 16.7 13.8 9.9 5.8 0.5 8.1 13.7 0.9 0.8 14.9 9.2 2.4 9.1 21.6 12.4 23.7 10.1 5.9 16.4 4.8 9.8 8.7 8.3 16.8 13.9 7.4 3.0 7.8 4.4 6.5 8.9 6.1 3.5 9.6 6.1 7.5 4.7 8.7 9.9 9.8 18.1 4.5 5.4 13.4 5.1 11.5 10.7 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 HAUS1 "CCDC5, FLJ40084, HEI-C, HsT1461" ENSG00000152240 "HAUS augmin like complex subunit 1" Q96CS2 18 46104378-46128333 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040601, HPA040652" Supported Supported Centrosome,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Centrosome "HPA040601: AB_10794743, HPA040652: AB_10793966" "unprognostic (1.74e-2)" "unprognostic (1.89e-2)" "unprognostic (8.13e-3)" "unprognostic (1.92e-1)" "unprognostic (2.29e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (1.39e-1)" "unprognostic (4.76e-3)" "prognostic favorable (1.55e-4)" "unprognostic (3.75e-1)" "prognostic unfavorable (6.76e-4)" "unprognostic (5.97e-3)" "unprognostic (5.40e-2)" "unprognostic (9.79e-3)" "unprognostic (3.66e-2)" "unprognostic (7.96e-2)" 14.3 11.0 7.2 18.4 7.2 37.8 18.9 7.3 10.2 13.7 9.0 18.5 14.3 17.0 38.7 14.5 13.4 16.9 11.8 7.0 7.8 13.0 13.7 12.2 35.6 7.5 7.6 26.4 11.4 14.3 10.7 17.8 7.8 10.4 22.1 9.5 10.5 12.9 7.2 10.1 14.3 16.8 8.0 14.6 13.0 16.2 7.3 41.4 13.3 13.2 39.5 16.2 11.9 8.1 72.8 43.6 157.3 86.9 38.8 59.4 42.5 68.4 65.7 105.5 104.4 43.2 39.5 136.4 40.5 48.3 49.8 74.6 94.0 56.4 115.1 77.7 64.2 99.2 40.7 82.0 32.5 184.2 59.7 28.6 21.6 64.6 33.3 45.6 115.1 91.5 72.4 39.8 94.2 41.9 150.0 87.7 101.1 33.0 24.9 144.6 112.4 98.4 85.4 49.9 74.3 77.2 64.3 22.3 52.9 60.7 33.3 89.0 67.9 62.8 42.1 27.9 73.4 43.5 73.2 130.6 39.9 157.0 74.0 11.1 46.5 36.7 40.3 45.4 45.0 79.4 53.0 48.9 58.3 64.8 38.1 45.0 4.9 55.9 35.8 62.5 99.9 55.4 7.2 7.2 7.3 10.2 7.0 7.8 7.5 7.6 7.8 8.0 7.3 8.1 20.6 12.8 12.2 3.3 26.5 17.5 15.8 47.8 16.5 6.1 16.4 18.7 10.1 15.7 33.0 14.7 4.2 58.7 22.0 11.1 17.6 38.2 7.5 15.9 18.3 29.4 12.1 53.9 4.2 42.3 111.7 25.1 7.1 14.5 29.8 31.3 23.2 6.9 50.9 11.8 4.8 24.1 28.5 33.6 24.7 12.4 22.7 25.8 21.4 4.7 45.8 21.5 37.0 8.0 5.2 31.8 12.4 25.9 21.9 8.1 14.3 24.7 29.3 8.7 19.7 15.9 20.2 50.8 55.8 15.3 15.5 23.7 23.9 20.7 26.8 12.9 HAUS8 "HICE1, MGC20533, NY-SAR-48" ENSG00000131351 "HAUS augmin like complex subunit 8" Q9BT25 19 17049729-17075625 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 40.4;Spermatogonia: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039406 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA039406: AB_10794090" "unprognostic (1.14e-1)" "prognostic favorable (9.54e-4)" "unprognostic (8.73e-2)" "unprognostic (5.74e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-2)" "unprognostic (1.74e-3)" "unprognostic (1.19e-1)" "unprognostic (1.04e-2)" "unprognostic (8.81e-2)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (8.35e-13)" "unprognostic (7.46e-3)" "unprognostic (1.28e-1)" "unprognostic (2.75e-3)" "unprognostic (2.17e-3)" 3.5 4.6 1.1 7.5 1.1 11.5 3.3 1.6 1.4 2.0 0.9 5.6 5.1 2.8 2.5 3.0 2.2 2.7 2.9 1.1 1.3 2.1 4.6 3.1 14.6 1.3 1.2 2.5 1.9 2.5 1.8 5.4 1.2 2.3 5.0 1.0 2.7 2.7 3.4 3.8 4.6 2.8 1.0 6.9 3.6 10.7 1.3 9.5 2.4 2.6 14.3 3.5 1.9 1.3 29.8 19.2 28.5 29.5 5.2 5.0 58.1 29.5 14.7 44.4 44.0 29.9 19.0 59.8 29.7 12.9 12.7 28.3 29.2 14.7 33.4 34.6 32.6 37.3 20.1 20.7 2.9 24.9 34.2 1.5 3.9 27.8 9.2 4.7 17.8 27.4 31.8 27.5 24.9 37.6 42.2 28.5 29.5 34.0 36.7 38.5 29.8 24.7 10.5 21.2 26.7 16.1 27.8 17.0 15.5 18.2 19.5 21.5 11.2 27.8 18.7 48.6 40.4 14.9 21.3 40.6 15.2 47.5 25.2 0.2 5.1 5.6 5.4 15.0 5.9 12.0 6.4 7.0 3.6 11.0 8.6 5.7 3.3 7.7 14.2 4.4 11.1 5.1 1.1 1.1 1.6 1.4 1.1 1.3 1.3 1.2 1.2 1.0 1.3 1.3 3.2 3.2 2.8 1.0 12.0 6.6 13.5 10.2 6.2 2.9 4.4 5.2 4.5 7.2 5.1 1.8 2.1 25.1 6.2 8.5 5.9 7.2 12.6 3.7 5.9 3.8 0.0 18.1 2.0 7.8 25.4 7.8 1.5 4.6 4.5 7.8 4.6 4.2 12.1 1.7 2.3 7.9 14.2 8.5 12.1 3.2 5.9 12.2 10.6 2.8 6.4 2.6 5.2 2.0 3.2 7.0 3.0 3.8 4.4 5.5 5.3 3.0 3.5 6.3 6.6 4.2 6.1 40.4 47.0 4.7 4.5 9.9 7.5 5.6 6.5 5.1 HELLS "LSH, Nbla10143, PASG, SMARCA6" ENSG00000119969 "Helicase, lymphoid specific" Q9NRZ9 10 94501434-94613905 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Developmental protein, Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 182.0;Spermatogonia: 173.9" "Cancer enhanced" "Detected in all" "testis cancer: 16.1" "Region enhanced" "Detected in many" "cerebellum: 5.5" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 36.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004491, HPA063242" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" No Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB004491: AB_627895, HPA063242: AB_2684968" "unprognostic (1.94e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.85e-2)" "unprognostic (3.38e-2)" "unprognostic (8.65e-2)" "unprognostic (4.85e-3)" "unprognostic (1.76e-5)" "unprognostic (7.59e-3)" "unprognostic (7.03e-3)" "unprognostic (6.49e-2)" "unprognostic (2.05e-2)" "unprognostic (9.45e-5)" "unprognostic (9.93e-13)" "unprognostic (2.25e-2)" "unprognostic (1.72e-1)" "unprognostic (6.24e-2)" "unprognostic (3.03e-2)" 1.1 1.2 0.8 6.4 0.3 16.3 3.0 5.5 1.2 3.2 1.3 4.3 2.9 2.9 1.4 5.9 1.7 2.0 0.7 0.4 1.3 2.5 1.8 1.7 12.4 0.8 0.8 2.6 1.2 1.4 3.0 4.1 1.0 2.1 5.1 1.1 1.9 1.0 0.3 5.3 3.9 2.2 0.9 4.3 3.7 12.8 0.9 15.9 1.1 0.2 12.6 3.6 3.2 1.5 57.7 55.4 70.6 90.1 2.9 6.4 37.4 42.9 27.8 34.4 54.6 70.3 45.5 70.0 16.7 15.5 29.1 56.3 40.9 34.9 50.7 68.5 45.5 37.3 56.3 58.0 1.7 71.2 31.6 3.6 2.0 42.1 20.0 9.4 24.0 46.0 20.7 43.5 43.1 54.9 75.2 35.6 73.4 42.3 24.1 70.3 62.1 16.3 24.2 72.2 28.4 22.8 50.3 14.5 7.8 59.0 60.9 23.1 17.2 38.4 19.4 35.4 52.4 22.3 47.6 74.5 19.0 42.8 17.9 0.3 0.7 0.0 7.0 1.5 2.4 18.8 11.4 9.4 2.3 23.2 5.2 7.7 1.0 10.2 1.0 36.8 19.7 2.3 0.8 0.3 5.5 1.2 0.4 1.3 0.8 0.8 1.0 0.9 0.9 1.5 4.7 9.6 3.9 0.0 19.7 21.5 11.5 12.6 13.1 16.4 10.0 15.0 1.0 12.8 12.6 22.0 0.0 46.3 13.2 26.2 3.9 9.0 2.0 9.3 16.4 8.1 10.8 50.5 3.3 6.2 43.4 13.0 17.9 16.3 5.7 60.6 5.7 3.6 15.1 6.7 5.4 17.8 8.2 2.2 10.3 5.3 9.0 7.3 1.8 9.4 5.7 4.3 1.0 4.5 6.6 4.7 1.8 5.7 37.5 3.7 1.7 1.6 6.3 11.4 19.7 10.5 16.4 182.0 173.9 22.9 9.9 11.1 15.7 16.5 30.9 11.7 HIRIP3 ENSG00000149929 "HIRA interacting protein 3" Q9BW71 16 29992330-29996074 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 129.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051897, HPA063205" Approved Enhanced Nucleoplasm No No "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051897: AB_2681655, HPA063205: AB_2684963" "unprognostic (6.99e-2)" "prognostic favorable (2.74e-5)" "unprognostic (4.75e-2)" "unprognostic (2.83e-1)" "unprognostic (1.08e-1)" "unprognostic (4.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.80e-2)" "unprognostic (3.58e-2)" "unprognostic (8.53e-3)" "unprognostic (3.85e-2)" "unprognostic (2.07e-1)" "unprognostic (4.26e-3)" "unprognostic (5.22e-2)" "unprognostic (1.69e-1)" "unprognostic (1.97e-2)" "unprognostic (2.35e-2)" 12.3 11.6 24.4 9.0 25.5 15.8 11.8 23.9 24.7 13.3 19.0 16.0 8.3 13.5 10.6 9.6 12.2 7.1 19.2 22.9 23.8 12.6 14.9 11.6 13.1 25.5 24.6 16.8 11.0 15.6 14.5 6.8 25.4 11.9 7.3 20.1 11.1 12.8 33.5 14.6 10.9 8.6 24.1 12.9 10.6 38.7 24.4 25.6 11.7 21.7 12.3 14.2 11.5 25.7 27.4 27.7 44.2 28.5 13.9 14.8 13.4 20.9 16.1 21.2 18.2 24.8 26.8 52.7 42.5 13.7 15.3 19.0 28.8 26.6 15.8 47.8 28.1 56.7 36.2 26.9 11.5 50.3 42.4 7.4 19.4 20.9 32.3 12.4 13.4 50.6 27.2 57.0 12.9 20.0 66.1 26.3 13.0 17.8 15.5 65.9 52.6 52.5 14.9 12.2 28.6 34.7 21.7 16.3 14.5 11.3 24.2 30.6 15.4 28.4 21.8 20.3 20.5 37.1 31.0 31.4 26.8 43.2 38.1 4.6 7.5 15.0 16.7 12.0 11.4 19.1 18.6 15.3 6.3 14.6 19.3 17.9 3.4 14.3 20.8 19.1 22.9 10.8 24.4 25.5 23.9 24.7 22.9 23.8 25.5 24.6 25.4 24.1 24.4 25.7 19.1 67.3 26.3 2.0 14.9 12.7 17.1 11.2 14.8 36.4 14.6 19.6 30.4 10.0 15.8 9.2 14.6 30.6 18.7 12.5 29.4 10.5 27.6 12.6 10.9 15.4 9.6 27.0 2.1 12.1 28.9 14.6 4.6 10.9 31.0 12.1 10.8 16.7 18.7 15.2 2.7 10.8 14.2 8.2 11.9 12.0 20.5 9.8 5.4 1.0 8.8 37.3 32.0 3.5 4.7 6.3 11.4 22.6 22.0 6.7 25.6 19.9 19.9 49.4 13.1 14.7 18.6 129.5 46.2 10.2 11.4 11.5 20.9 12.1 14.0 8.3 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HMGB1 "DKFZp686A04236, HMG1, HMG3, SBP-1" ENSG00000189403 "High mobility group box 1" P09429 13 30456704-30617597 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Autophagy, Chemotaxis, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB005873, HPA073663" Supported Supported Nucleoplasm "Secreted to blood" NA NA 2800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB005873: AB_444360, HPA003506: AB_1079070, HPA073663: " "unprognostic (9.56e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-1)" "unprognostic (4.44e-2)" "unprognostic (4.29e-2)" "unprognostic (3.16e-2)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" "unprognostic (1.73e-1)" "unprognostic (2.64e-2)" "unprognostic (2.30e-2)" "unprognostic (4.28e-3)" "unprognostic (5.22e-3)" "unprognostic (4.67e-1)" "unprognostic (9.13e-3)" "unprognostic (1.97e-2)" 312.0 224.3 266.2 355.1 282.2 1021.3 318.2 267.6 362.4 319.0 227.0 327.8 281.9 363.6 270.1 297.0 265.5 227.0 242.2 250.1 282.9 243.7 360.8 242.2 664.8 281.5 273.3 254.9 189.3 226.1 163.3 252.1 286.2 265.9 381.2 174.8 224.5 280.1 388.5 244.2 309.2 319.5 277.7 284.9 269.0 153.9 269.9 900.3 267.4 364.7 738.9 282.7 274.1 308.2 816.7 617.4 1402.5 1054.0 384.5 380.1 551.4 1012.6 547.9 957.3 643.5 983.6 1328.6 1639.3 515.5 924.0 880.6 886.5 1484.7 817.4 1639.6 869.6 622.4 1727.4 455.4 913.5 210.3 2513.6 1009.8 253.4 426.0 713.3 656.6 497.8 1302.2 1350.8 1167.9 571.7 855.6 1508.3 3224.3 2682.1 1184.3 1424.3 683.7 2673.3 1927.8 965.8 908.1 792.8 1264.0 1139.8 928.6 682.0 541.0 672.3 668.5 1857.9 814.7 637.2 921.8 689.7 1197.1 513.9 714.8 3508.3 261.1 1634.0 1369.3 1036.6 503.7 926.1 467.3 410.9 522.1 582.6 532.3 530.7 520.1 590.7 477.4 459.7 631.7 615.4 411.0 512.5 702.6 1072.0 266.2 282.2 267.6 362.4 250.1 282.9 281.5 273.3 286.2 277.7 269.9 308.2 948.9 458.3 496.6 188.4 920.7 791.1 986.7 942.7 752.4 414.3 471.9 630.0 172.5 561.9 561.3 603.2 131.3 998.9 759.9 408.1 766.9 941.3 113.4 611.2 1040.2 766.0 423.0 1808.9 58.5 967.2 1441.4 676.5 486.3 728.3 546.8 772.2 589.0 749.5 728.8 196.9 47.2 675.6 710.1 549.9 884.4 107.2 720.1 694.2 674.1 81.5 578.7 609.9 879.5 99.5 149.3 1212.3 554.8 666.9 1252.9 811.2 506.7 827.5 418.7 252.8 650.8 588.9 1005.9 549.1 1211.0 1045.8 691.9 465.7 797.9 515.7 839.1 867.9 HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2347.2;lymphoid tissue: 939.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 1915.4;Extravillous trophoblasts: 872.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 798.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 2454.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli "Secreted to blood" NA Yes 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB037206: AB_1079071, HPA003506: AB_1079070, HPA053314: AB_2682109, HPA073663: " "unprognostic (2.82e-1)" "unprognostic (8.52e-3)" "unprognostic (2.56e-1)" "unprognostic (8.37e-2)" "unprognostic (8.05e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (7.60e-12)" "unprognostic (1.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.68e-2)" "unprognostic (1.21e-2)" 90.3 31.0 36.3 146.1 38.4 2347.2 89.1 35.4 49.9 79.0 33.0 117.1 93.2 92.3 47.3 115.6 78.8 43.5 85.8 33.2 38.3 74.3 37.8 83.8 390.4 37.5 36.8 118.9 27.2 18.3 35.4 111.0 38.0 46.9 122.2 134.1 59.8 35.2 72.4 75.1 108.7 65.5 36.3 159.5 66.0 136.0 36.1 939.2 56.4 57.0 388.9 68.2 86.1 40.1 498.2 114.6 976.8 444.4 118.2 118.2 375.1 366.3 271.3 386.7 345.7 329.0 673.6 1645.5 79.2 203.0 207.4 190.3 645.0 196.1 601.0 1004.0 303.4 1823.2 308.8 487.8 115.7 1642.8 683.4 114.7 59.2 194.2 439.1 211.5 402.8 866.1 703.9 2282.4 358.9 409.9 2454.9 1513.7 355.4 289.4 199.3 1226.7 499.7 620.4 227.0 208.8 838.6 759.0 365.5 209.6 166.6 340.8 291.1 1173.2 236.0 175.5 513.6 219.0 554.9 734.8 437.1 1869.4 149.1 1178.4 464.4 798.0 135.9 407.0 94.1 57.6 86.2 72.5 137.8 131.1 112.8 57.6 88.4 85.3 316.7 83.0 49.1 43.2 266.4 107.6 36.3 38.4 35.4 49.9 33.2 38.3 37.5 36.8 38.0 36.3 36.1 40.1 167.0 28.9 64.1 5.9 153.2 158.8 141.5 131.8 75.1 48.9 75.3 107.8 229.0 38.6 78.3 55.2 35.5 472.6 222.9 116.5 142.8 25.9 30.4 71.2 71.7 128.0 74.7 1915.4 2.7 16.1 872.5 121.5 63.2 76.5 110.6 210.5 171.7 26.5 210.1 45.4 4.7 191.2 109.9 295.0 142.9 33.1 105.3 233.9 67.6 6.5 241.9 81.8 132.8 1.0 4.8 11.3 75.2 57.6 268.6 114.2 65.4 51.0 149.8 143.5 78.9 71.7 134.4 493.6 400.9 233.6 134.0 128.7 289.5 42.3 284.7 89.0 HMGN2 HMG17 ENSG00000198830 "High mobility group nucleosomal binding domain 2" P05204 1 26472440-26476642 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB018371, HPA077364" Supported Supported Nucleoplasm,Nucleoli NA NA 640000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB018371: , HPA077364: AB_2686835" "unprognostic (3.10e-2)" "unprognostic (6.88e-2)" "unprognostic (3.10e-3)" "unprognostic (4.13e-2)" "unprognostic (4.06e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (2.36e-1)" "unprognostic (2.44e-3)" "unprognostic (2.86e-2)" "unprognostic (1.05e-3)" "unprognostic (5.23e-3)" "prognostic unfavorable (3.92e-4)" "unprognostic (3.00e-2)" "unprognostic (2.54e-1)" "unprognostic (8.21e-2)" "unprognostic (1.15e-1)" 216.3 225.6 180.2 254.5 187.3 1137.3 234.8 179.6 251.3 328.1 162.5 280.3 176.3 283.8 359.3 291.1 293.4 142.9 192.5 170.6 183.1 259.7 212.9 259.2 436.5 185.1 178.8 394.6 252.5 160.4 328.7 214.9 188.4 281.6 301.1 285.0 217.1 162.8 251.8 242.8 270.0 235.8 188.7 324.3 224.7 160.4 175.8 916.1 306.1 133.5 534.0 245.1 250.7 211.6 1074.5 304.8 1192.5 496.5 112.0 251.6 390.8 517.2 331.2 1089.4 835.7 305.8 1073.1 1107.2 443.1 482.3 338.4 627.8 1564.6 565.6 1001.7 684.2 906.7 1222.2 401.5 360.2 197.7 2793.6 738.7 254.9 303.4 602.1 369.1 245.1 541.7 866.8 964.3 643.0 623.0 690.8 1906.1 1363.3 922.7 1463.0 619.6 1384.3 1598.6 776.5 380.3 278.6 1064.5 641.1 1384.3 498.7 651.4 304.9 759.0 1508.9 322.3 536.9 920.4 977.1 943.6 641.2 899.2 1266.9 338.9 2989.0 1056.9 331.8 530.8 1430.5 279.2 622.3 267.3 532.2 379.7 343.3 531.5 505.6 412.4 337.7 462.4 355.5 690.4 704.7 746.7 1084.6 180.2 187.3 179.6 251.3 170.6 183.1 185.1 178.8 188.4 188.7 175.8 211.6 128.7 342.9 394.4 28.1 459.3 288.6 323.8 383.2 211.1 180.2 353.0 241.3 93.4 221.6 314.8 261.1 141.8 898.7 325.2 227.2 371.7 218.4 204.3 328.9 291.1 190.3 576.9 980.4 14.4 268.7 606.4 435.4 263.5 278.1 383.0 375.0 185.6 147.5 763.0 94.2 22.2 564.5 193.3 434.3 467.9 53.5 185.8 477.5 227.7 15.0 655.6 376.0 399.6 15.1 36.9 93.7 304.4 151.9 669.5 250.4 238.0 320.4 495.6 370.2 124.9 249.0 325.7 306.4 412.0 585.8 213.4 923.4 369.5 351.9 613.2 314.0 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123998-62153169 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.9" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "basophil: 1.2;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;NK-cells: 1.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: AB_2533405, HPA051339: AB_2732566, HPA070550: AB_2686279" "unprognostic (6.31e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-3)" "unprognostic (7.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (1.74e-2)" "unprognostic (1.08e-3)" "unprognostic (1.17e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (2.78e-3)" 3.1 2.5 2.7 7.5 1.1 20.9 2.8 6.2 3.0 4.6 0.0 4.8 6.8 3.0 8.1 14.0 3.5 2.2 2.8 2.9 0.5 2.4 1.9 3.0 11.6 1.6 0.8 3.8 3.1 3.1 1.5 4.1 1.3 2.5 3.6 3.4 6.1 2.9 4.2 7.9 5.7 3.4 0.1 5.5 4.5 6.4 0.5 17.8 5.1 3.4 8.2 2.8 5.5 1.2 74.3 69.4 51.6 45.5 6.8 8.4 28.1 47.6 21.2 44.4 28.3 37.0 50.7 70.0 36.2 16.0 46.2 72.6 52.2 28.4 31.8 60.5 36.6 45.7 68.0 29.6 2.7 53.5 62.1 4.3 6.5 41.3 23.6 6.8 25.8 50.2 48.8 57.6 25.3 59.7 85.0 43.3 56.2 28.0 34.4 79.3 66.4 53.4 12.0 35.8 40.1 42.2 46.8 30.8 27.9 19.8 48.2 19.4 28.5 41.8 51.9 59.8 50.0 29.7 48.3 75.8 23.5 34.7 50.6 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.7 1.1 6.2 3.0 2.9 0.5 1.6 0.8 1.3 0.1 0.5 1.2 1.2 3.2 2.3 1.3 3.4 5.6 0.8 1.0 2.8 2.4 1.1 0.6 1.3 0.0 3.7 0.0 0.0 4.2 4.2 5.4 0.0 1.9 1.0 2.0 2.1 1.5 0.0 10.9 3.3 2.5 7.1 1.9 9.2 2.7 3.8 5.7 0.0 0.7 4.2 0.0 2.5 3.4 0.0 0.9 1.6 0.5 2.8 3.3 3.6 1.0 5.0 1.5 3.1 2.0 1.5 2.2 1.6 1.5 10.9 1.2 1.3 0.3 2.6 2.3 0.0 1.9 4.3 6.5 7.8 15.1 3.3 2.2 3.7 1.9 4.8 1.1 ITGB3BP "CENPR, HSU37139, NRIF3, TAP20" ENSG00000142856 "Integrin subunit beta 3 binding protein" Q13352 1 63440770-63593721 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028463 Approved Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028463: AB_10601435" "unprognostic (4.98e-2)" "unprognostic (5.88e-3)" "unprognostic (6.28e-3)" "unprognostic (3.96e-2)" "unprognostic (4.58e-1)" "prognostic favorable (4.32e-4)" "prognostic unfavorable (7.24e-5)" "unprognostic (2.68e-2)" "unprognostic (7.89e-3)" "unprognostic (2.15e-2)" "unprognostic (1.35e-1)" "unprognostic (4.97e-3)" "prognostic unfavorable (8.45e-6)" "unprognostic (1.34e-2)" "unprognostic (5.24e-2)" "unprognostic (7.34e-3)" "unprognostic (6.14e-2)" 6.8 11.5 2.3 7.9 2.3 11.9 15.0 2.5 4.6 7.8 3.7 10.7 8.0 8.8 15.9 9.0 9.3 10.8 4.4 2.2 2.5 12.6 6.4 7.2 18.0 2.5 2.4 14.1 10.1 18.2 5.3 10.1 2.5 8.7 10.1 2.8 7.8 6.2 2.5 9.1 6.0 5.6 2.4 8.9 8.0 20.6 2.3 20.2 13.5 4.4 16.4 10.1 8.3 2.6 63.6 32.9 35.9 28.6 8.6 25.2 32.3 30.3 18.7 51.6 63.4 18.2 29.0 57.4 22.6 7.3 26.2 44.3 28.2 30.8 63.7 43.4 74.2 43.9 41.3 35.1 9.2 60.4 27.6 6.5 22.4 29.9 23.5 24.3 26.6 34.5 51.5 74.6 7.3 27.8 66.4 57.0 45.5 24.1 38.2 42.5 61.4 84.7 34.8 19.4 46.1 28.8 34.7 20.0 50.4 53.0 19.9 20.0 16.1 17.9 26.1 36.6 46.2 37.1 64.1 54.4 30.0 75.4 27.7 14.2 4.0 1.4 6.5 3.2 11.3 15.9 10.2 10.6 5.1 15.4 11.3 10.2 1.1 15.6 3.9 8.8 12.2 6.7 2.3 2.3 2.5 4.6 2.2 2.5 2.5 2.4 2.5 2.4 2.3 2.6 22.0 9.6 13.9 24.2 40.9 33.9 56.3 49.8 34.7 10.7 35.9 43.7 11.5 28.6 38.2 25.8 10.4 45.9 19.3 10.1 29.4 42.2 100.8 45.2 22.1 21.6 17.4 40.0 23.6 34.3 56.3 28.6 20.4 21.1 23.5 40.7 23.9 9.7 30.0 6.7 23.6 18.1 42.7 21.0 26.1 121.4 21.5 18.9 21.4 15.0 23.7 21.2 30.9 18.6 31.0 24.8 4.1 25.9 30.7 13.7 6.0 39.1 54.3 15.8 32.9 18.2 21.9 200.5 54.4 30.8 32.7 19.2 26.6 13.6 31.9 35.8 KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 37.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 39.1;Granulosa cells: 20.7;Spermatocytes: 38.0;Spermatogonia: 23.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Mitotic spindle" "CAB017617: AB_2131098, HPA006916: AB_1848033, HPA010093: AB_2668281, HPA010568: AB_1848034" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (8.19e-7)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (6.59e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.35e-3)" "unprognostic (7.23e-2)" "unprognostic (9.08e-2)" "unprognostic (2.01e-1)" 1.1 0.7 0.5 8.5 0.7 19.4 2.5 0.4 0.6 1.4 0.5 6.3 5.5 1.8 1.0 6.7 1.0 1.2 0.6 0.5 0.5 1.0 1.1 1.3 17.5 0.6 0.6 0.6 0.5 0.7 0.3 3.9 0.6 1.0 7.4 0.8 1.3 0.7 0.2 6.0 5.3 2.5 0.5 2.9 3.9 11.6 0.4 37.9 1.6 0.3 18.5 2.3 2.3 0.6 103.1 45.2 100.6 94.5 7.3 10.5 24.2 72.6 62.8 78.8 78.1 39.6 67.2 111.1 36.5 34.4 32.9 72.0 72.1 36.5 92.4 68.3 41.3 70.5 41.4 42.4 1.4 116.0 63.0 3.6 3.3 61.4 55.9 18.3 50.0 46.1 51.2 126.4 61.1 41.4 99.3 65.8 40.3 42.5 30.7 106.6 98.8 40.2 21.0 30.1 30.0 42.9 56.4 25.9 29.2 34.1 67.9 37.6 28.6 35.7 51.3 37.1 96.9 35.4 58.3 113.4 29.5 82.3 50.3 0.8 0.0 0.1 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.1 0.2 0.2 1.0 0.1 0.1 1.1 0.2 0.5 0.7 0.4 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.4 0.6 0.4 0.0 2.0 1.3 3.5 2.9 1.1 1.6 3.4 1.0 1.8 1.8 1.7 1.5 2.5 1.8 0.0 6.7 2.3 2.9 1.9 0.5 16.3 3.4 4.3 2.0 0.0 39.1 2.1 0.6 11.4 4.7 9.2 4.9 0.0 20.7 2.2 0.4 8.2 0.0 1.8 4.3 4.1 4.6 3.4 4.4 0.9 4.0 0.0 0.0 1.0 0.7 2.1 2.5 1.1 0.2 0.4 0.7 15.2 0.8 0.5 0.6 3.7 0.4 0.0 1.7 3.7 38.0 23.4 12.6 3.3 1.5 4.5 2.5 8.0 1.7 KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.1;Granulosa cells: 13.2;Spermatocytes: 22.8;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" 0.2 0.2 0.1 2.0 0.0 6.5 0.3 0.2 0.3 0.2 0.1 0.9 1.2 0.3 0.0 1.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.2 3.2 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.2 0.1 0.1 0.0 0.0 1.0 1.1 0.6 0.0 0.6 0.6 2.5 0.1 10.9 0.1 0.0 3.2 0.4 0.3 0.1 29.7 17.3 26.8 15.0 0.8 3.0 14.8 20.0 11.7 18.7 16.8 10.5 15.1 18.0 7.0 9.6 11.6 23.0 21.6 13.3 26.7 22.1 11.3 28.8 24.8 10.3 0.1 45.5 15.7 0.6 0.6 20.9 17.8 4.0 13.5 26.3 44.0 22.6 23.5 12.1 26.9 14.2 22.6 8.7 15.0 24.3 35.4 22.8 6.3 8.3 12.7 14.0 28.3 9.5 11.0 19.8 12.9 11.6 11.1 14.7 17.3 16.2 35.3 8.2 8.9 25.8 8.6 24.0 30.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 1.9 2.4 1.0 1.1 0.6 2.3 1.5 1.9 0.8 0.0 0.9 0.0 2.1 4.2 0.6 2.5 0.0 0.2 4.1 3.7 2.2 1.6 0.0 27.1 1.1 0.0 7.7 3.3 10.2 5.0 2.5 13.2 2.5 0.9 5.4 0.0 0.9 5.2 0.0 2.9 1.9 2.5 0.6 2.3 0.0 0.0 0.4 0.5 0.0 0.5 0.8 0.3 0.0 0.7 11.3 1.2 0.2 0.1 1.4 0.8 6.6 1.4 2.1 22.8 16.3 8.3 0.9 1.4 2.3 0.7 4.3 1.9 KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020619-28108156 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 8.2;lymphoid tissue: 9.6;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 43.1;Spermatocytes: 78.7;Spermatogonia: 28.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.1;memory B-cell: 1.0;NK-cell: 1.4;T-reg: 1.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Cytokinetic bridge" "HPA039312: AB_10794087, HPA039484: AB_10795252" "unprognostic (3.79e-1)" "unprognostic (2.63e-1)" "unprognostic (7.09e-3)" "unprognostic (3.80e-2)" "unprognostic (6.56e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-7)" "unprognostic (2.43e-3)" "unprognostic (2.04e-3)" "unprognostic (1.23e-2)" "unprognostic (1.72e-4)" "unprognostic (4.41e-2)" "unprognostic (0.00e+0)" "unprognostic (7.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" 0.2 0.1 0.0 1.9 0.1 8.2 0.7 0.0 0.1 0.7 0.1 1.6 1.5 0.5 0.3 1.4 0.3 0.5 0.0 0.1 0.1 0.3 0.3 1.0 4.7 0.1 0.1 0.1 0.1 0.1 0.1 1.5 0.1 0.3 2.0 0.6 0.3 0.4 0.2 1.2 1.4 0.8 0.1 0.7 0.6 13.7 0.2 9.6 1.1 0.1 4.6 0.7 0.5 0.1 27.9 27.4 27.2 19.0 0.9 3.7 9.1 28.3 13.2 44.2 46.0 9.2 11.0 23.3 10.0 14.7 24.1 27.2 23.4 11.1 61.4 23.4 14.2 15.2 17.8 11.8 2.1 22.6 13.4 6.8 1.4 15.5 18.1 7.8 17.2 19.0 24.6 20.0 25.2 14.8 23.1 16.7 13.4 18.0 11.1 17.8 65.0 11.6 12.5 8.0 16.3 12.6 23.7 11.1 7.8 16.5 23.8 6.9 10.1 35.0 27.2 33.2 37.4 7.9 19.8 23.4 21.0 16.5 25.2 4.1 0.0 0.3 0.1 0.2 0.3 1.0 0.4 0.2 0.3 0.4 0.3 0.1 0.0 1.4 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 1.2 3.2 0.0 0.0 4.7 2.3 1.3 1.4 1.2 0.3 1.3 2.9 0.5 0.0 2.2 0.0 6.2 4.6 2.8 1.9 0.0 0.6 43.1 3.4 2.5 1.1 1.8 15.4 0.2 0.9 7.1 5.4 1.5 3.4 4.5 9.7 1.4 0.0 2.2 0.0 0.1 1.9 0.0 1.6 1.4 8.7 0.6 1.4 0.0 1.0 1.1 0.7 1.0 0.5 0.9 0.5 0.1 0.4 5.1 0.2 0.2 0.6 1.7 1.9 0.0 2.5 1.9 78.7 28.3 4.3 1.0 1.6 3.9 2.7 3.6 0.5 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.0;Extravillous trophoblasts: 3.8;Granulosa cells: 5.9;Oligodendrocyte precursor cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.4 0.4 0.3 3.8 0.4 12.7 0.2 0.7 0.3 0.9 0.3 2.0 2.7 0.4 0.0 5.1 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.8 5.7 0.5 1.1 0.1 0.1 0.0 0.1 1.9 0.6 0.2 1.7 0.1 0.7 0.0 0.4 3.0 2.5 1.1 0.3 2.9 1.5 2.9 0.6 14.4 0.2 0.0 4.7 0.6 1.6 0.5 31.5 41.7 35.3 32.8 0.8 3.0 28.1 25.8 10.3 34.6 26.9 34.0 27.4 28.3 10.9 10.8 21.5 34.0 25.1 11.3 17.9 56.6 36.4 35.4 51.7 22.1 0.0 30.0 30.2 0.7 0.6 29.7 12.2 4.7 17.9 29.2 28.1 48.0 18.2 25.9 60.0 31.1 25.4 30.4 28.9 43.5 51.8 19.2 5.8 16.7 26.2 24.7 18.0 16.1 9.8 17.0 30.2 21.6 11.2 49.9 48.0 28.8 56.8 15.1 15.7 34.4 16.3 22.9 33.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.7 0.3 0.3 0.4 0.5 1.1 0.6 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.2 0.0 0.5 0.5 0.4 2.6 0.0 0.0 0.0 0.0 2.4 0.4 1.9 0.0 0.0 0.0 0.3 0.8 0.6 0.0 9.0 0.3 0.0 3.8 1.4 1.5 0.5 0.0 5.9 0.4 0.3 2.3 0.0 0.3 1.6 0.0 2.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 7.1 0.1 0.1 0.0 0.0 2.1 0.2 0.3 0.0 0.0 0.3 0.0 0.2 0.8 1.1 2.9 2.5 0.4 0.8 1.3 0.3 3.2 0.3 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.2;lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 89.2;Spermatocytes: 165.4;Spermatogonia: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 1.3 0.7 0.3 4.5 1.0 10.2 2.5 2.4 0.4 1.5 0.1 3.2 3.6 2.3 0.4 3.3 1.2 1.3 0.9 0.3 0.3 1.3 1.3 1.5 8.0 0.5 0.3 2.7 0.7 1.1 0.2 2.4 0.6 1.3 4.0 1.1 1.0 0.9 0.4 2.5 3.4 2.2 0.4 3.3 2.5 6.9 0.6 9.8 1.8 0.7 7.5 1.6 0.7 0.6 84.8 17.0 24.3 21.7 4.7 8.0 20.2 33.8 30.9 34.8 36.3 22.6 38.1 32.5 10.4 17.3 13.0 41.8 27.3 18.9 46.4 39.5 18.6 33.1 30.5 19.5 1.4 57.1 26.3 3.4 2.8 33.7 33.9 12.2 22.8 17.0 32.2 36.5 31.3 14.6 33.6 10.8 25.0 13.8 16.1 23.1 47.8 14.3 10.7 11.2 7.7 13.9 24.4 11.0 12.2 17.3 28.5 16.3 17.9 22.2 22.1 29.1 55.3 10.1 29.5 43.2 21.1 49.4 16.8 13.1 2.4 4.2 5.5 4.1 6.8 13.0 7.4 6.1 1.3 16.0 8.6 8.0 0.2 3.0 4.5 5.2 9.5 2.2 0.3 1.0 2.4 0.4 0.3 0.3 0.5 0.3 0.6 0.4 0.6 0.6 11.5 3.2 13.5 2.3 36.4 17.7 6.2 20.8 6.8 14.3 8.3 8.5 8.7 1.5 10.7 0.0 10.4 21.4 32.3 8.8 3.9 6.9 13.1 10.6 13.2 11.0 1.2 89.2 8.1 4.7 38.1 13.2 14.8 12.9 44.4 37.2 9.3 4.4 20.7 13.5 9.5 8.6 16.2 21.0 17.9 10.5 8.1 17.1 5.4 23.4 11.3 7.5 24.7 9.0 9.1 4.1 5.7 8.6 51.4 3.7 8.9 3.2 6.6 9.8 6.6 16.9 17.1 165.4 96.7 26.1 14.1 5.2 34.2 12.9 25.5 5.2 KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.2;Erythroid cells: 42.3;Extravillous trophoblasts: 32.4;Granulosa cells: 22.4;Spermatocytes: 70.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Group enriched" "Detected in many" 13 "granulocytes: 4.6;monocytes: 1.2;T-cells: 1.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB010414, HPA045208, HPA068831" Uncertain Enhanced "Nucleoplasm,Midbody ring,Mitotic spindle" Yes Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Midbody ring, Mitotic spindle" "CAB010414: AB_631959, HPA045208: AB_2679254, HPA068831: AB_2686045" "unprognostic (1.29e-1)" "unprognostic (2.40e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.86e-1)" "unprognostic (7.99e-3)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.43e-3)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (5.85e-3)" "unprognostic (0.00e+0)" "unprognostic (1.15e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" 1.0 1.5 0.3 5.7 0.2 21.6 1.4 0.2 0.3 1.5 1.4 4.1 3.9 2.0 0.1 5.3 0.9 1.3 0.6 0.3 0.2 4.6 0.5 1.5 7.9 0.2 0.3 0.7 0.5 0.4 0.1 6.4 0.3 0.9 5.0 0.2 1.1 1.2 0.1 3.7 3.8 4.2 0.2 2.2 2.0 10.6 0.3 15.9 0.3 0.2 9.8 1.8 2.1 0.2 100.7 81.5 64.2 59.0 3.7 7.3 36.3 105.3 57.0 154.8 120.6 50.2 72.4 56.8 31.4 53.1 78.6 110.5 121.6 39.5 158.7 52.9 60.2 55.3 78.8 30.7 2.1 55.6 48.3 3.3 4.2 71.8 60.5 19.4 52.0 46.9 36.0 70.2 95.4 44.1 31.2 28.2 71.6 35.5 33.2 37.0 133.8 31.2 39.3 49.7 32.5 25.3 120.4 51.9 44.9 74.5 50.6 25.3 34.5 90.0 120.8 62.0 157.6 26.3 74.3 48.4 31.5 72.2 78.0 0.0 1.2 4.6 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.2 0.4 0.0 0.5 0.0 2.3 1.9 3.7 4.2 0.0 0.2 1.8 2.8 0.8 5.7 4.7 7.3 2.1 24.2 1.4 3.3 3.9 1.8 13.3 13.1 3.6 2.2 1.8 42.3 1.8 0.0 32.4 5.8 3.6 8.7 2.5 22.4 3.9 0.3 8.1 0.0 1.0 3.1 0.0 2.8 3.4 4.8 0.9 3.2 0.0 1.0 8.1 0.2 0.0 0.0 0.2 0.4 0.4 1.9 6.8 1.6 0.8 0.9 3.6 0.1 6.6 0.4 8.2 70.8 20.9 11.3 1.0 2.5 4.2 3.6 8.6 3.3 KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 12.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.6;Erythroid cells: 29.5;Extravillous trophoblasts: 11.5;Granulosa cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034745, HPA034746, HPA061583" Approved Supported Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (8.17e-3)" "unprognostic (2.78e-2)" "unprognostic (1.02e-2)" "unprognostic (3.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.37e-6)" "unprognostic (2.18e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (3.79e-2)" "unprognostic (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" 0.3 0.3 0.3 3.2 0.2 11.2 0.7 0.1 0.3 0.6 0.3 3.7 3.1 0.8 0.0 3.6 1.5 0.5 0.2 0.2 0.5 0.2 0.5 0.5 5.5 0.9 0.7 0.1 0.1 0.1 0.5 2.3 0.6 0.1 4.5 0.6 0.5 0.1 0.1 2.2 3.3 1.3 0.7 2.4 1.7 1.5 0.6 12.6 0.2 0.0 6.6 0.9 1.1 0.2 60.2 41.1 61.0 30.1 2.9 5.1 24.0 44.7 23.8 59.7 51.6 46.7 34.3 36.7 27.4 22.1 46.2 35.1 66.6 24.2 66.8 42.5 33.4 41.7 50.1 33.4 0.7 46.7 27.8 1.7 1.5 49.6 28.2 7.3 37.0 27.7 53.8 79.1 57.0 38.7 43.0 23.1 61.7 63.8 43.2 47.1 82.2 34.6 14.5 23.4 40.1 33.5 72.9 30.5 18.6 30.6 24.5 18.1 26.0 39.3 50.6 42.6 54.1 22.6 41.7 52.0 20.8 50.4 60.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.2 0.1 0.3 0.2 0.5 0.9 0.7 0.6 0.7 0.6 0.2 0.1 0.0 0.5 1.3 1.3 1.8 0.3 1.4 0.6 0.2 1.1 0.8 0.4 1.5 0.2 0.0 0.0 7.0 0.9 2.2 0.0 0.0 0.4 18.6 1.5 1.3 1.2 29.5 1.9 0.0 11.5 2.1 3.1 1.6 0.0 12.2 1.1 0.1 5.3 0.0 1.9 4.6 2.0 1.3 0.7 0.8 0.0 1.4 0.0 0.0 0.2 3.1 0.0 2.0 0.7 0.1 0.1 0.0 8.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 2.9 8.7 5.4 7.2 0.3 1.8 1.8 1.3 6.6 0.5 KIFC1 "HSET, KNSL2" ENSG00000237649 "Kinesin family member C1" Q9BW19 6 33391823-33409896 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 47.5" "Cell type enhanced" "Detected in many" "Early spermatids: 32.0;Erythroid cells: 62.3;Extravillous trophoblasts: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 1.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055997, HPA062674" Enhanced Approved Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA055997: AB_2683001, HPA062674: AB_2684829" "unprognostic (7.33e-2)" "unprognostic (1.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (7.07e-8)" "unprognostic (6.34e-3)" "unprognostic (9.36e-3)" "unprognostic (8.58e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.83e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.17e-2)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (4.52e-1)" 1.1 1.1 0.2 10.6 0.3 39.7 2.2 0.3 1.2 2.5 0.4 8.0 8.8 1.8 0.2 11.7 0.8 1.5 0.6 0.7 0.3 0.8 1.0 2.3 24.6 0.4 0.7 2.0 0.7 0.3 0.6 5.5 0.5 0.9 8.2 0.4 2.1 0.2 0.2 9.8 8.1 4.1 0.2 5.3 4.7 12.3 0.6 47.5 0.7 0.4 24.9 2.7 3.9 0.5 133.5 47.9 120.6 124.2 5.2 8.1 64.0 82.5 48.4 122.6 104.6 80.6 53.3 120.2 38.3 41.5 102.0 88.1 87.1 60.7 79.7 114.3 60.3 93.9 71.6 73.5 0.5 96.0 75.7 2.5 4.7 73.2 38.8 13.8 64.2 87.5 76.0 112.3 81.0 86.2 125.7 103.2 47.5 67.6 48.4 129.7 110.7 61.4 38.4 42.8 100.1 57.2 54.3 91.9 44.1 51.3 78.7 105.4 32.2 74.6 104.6 56.2 128.9 58.2 132.4 126.1 18.8 94.8 101.0 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.6 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.0 1.6 0.5 0.2 0.3 0.3 1.2 0.7 0.3 0.4 0.7 0.5 0.2 0.6 0.5 0.4 0.0 2.5 1.0 4.1 5.6 1.5 4.6 2.2 0.4 2.8 2.2 0.5 0.0 1.9 0.0 0.0 18.7 3.7 8.8 0.0 0.7 32.0 2.7 1.9 2.4 0.0 62.3 0.3 0.0 39.6 4.2 4.1 6.1 1.3 15.0 1.8 0.3 14.3 0.0 0.3 8.0 2.0 2.4 9.8 12.0 0.3 4.7 3.6 1.0 3.1 0.3 0.0 1.0 0.6 0.3 2.1 0.7 12.0 0.9 2.1 0.7 0.8 0.5 0.0 2.5 7.5 13.9 9.6 14.4 3.7 6.7 5.7 0.6 12.1 3.1 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Cell type enhanced" "Detected in many" "Early spermatids: 30.4;Erythroid cells: 29.5;Plasma cells: 28.7;Spermatocytes: 40.7;Spermatogonia: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA025241: AB_1852629" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-2)" "unprognostic (9.34e-2)" "prognostic favorable (8.69e-4)" "prognostic unfavorable (4.79e-6)" "unprognostic (4.04e-2)" "unprognostic (7.20e-3)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.89e-8)" "unprognostic (2.17e-2)" "unprognostic (3.08e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" 7.1 7.6 3.7 11.7 3.6 42.3 7.6 4.9 5.3 9.1 3.5 9.8 9.0 5.3 5.2 12.2 6.8 3.4 4.1 3.6 3.4 6.7 6.4 8.0 16.4 3.8 3.4 8.2 6.6 2.9 5.7 5.8 3.9 7.3 11.9 5.5 7.7 2.9 2.5 15.1 14.5 4.6 3.1 18.2 7.2 28.2 4.0 17.8 5.4 1.4 17.4 6.2 8.9 5.0 33.8 27.6 77.8 17.9 5.9 10.8 35.0 30.6 19.8 29.7 27.9 26.2 27.6 40.2 15.6 14.9 19.5 45.4 34.1 19.1 39.1 28.8 23.7 49.7 57.1 27.1 2.0 49.3 32.8 5.8 4.3 30.7 20.2 15.5 20.5 50.5 50.4 29.4 22.6 25.0 40.9 113.0 39.4 16.3 34.5 55.4 37.8 44.8 17.8 35.6 24.1 31.0 55.7 11.7 16.7 46.2 44.4 28.1 15.1 33.7 32.3 33.3 36.3 39.3 42.3 61.0 20.1 31.3 39.6 2.5 0.5 1.8 0.7 0.7 0.6 1.6 1.1 1.3 0.5 0.9 0.8 1.0 1.6 0.9 1.0 0.8 0.5 0.3 3.7 3.6 4.9 5.3 3.6 3.4 3.8 3.4 3.9 3.1 4.0 5.0 4.3 0.0 2.6 3.3 8.1 4.2 1.9 1.9 2.2 2.2 3.1 3.4 1.8 0.0 1.9 5.5 4.2 7.0 3.8 3.0 0.0 1.5 30.4 3.3 3.9 2.9 0.0 29.5 6.2 0.4 5.9 2.9 10.2 5.2 1.3 14.7 2.2 1.3 4.8 0.0 4.5 2.3 0.0 2.2 4.7 17.7 4.7 4.0 1.8 4.7 1.6 1.1 2.1 2.5 4.4 0.8 1.0 3.0 28.7 1.0 1.5 0.5 5.0 5.0 6.6 3.1 2.9 40.7 39.9 4.9 2.3 2.9 5.3 2.1 5.8 1.6 KPNA2 "IPOA1, QIP2, RCH1, SRP1alpha" ENSG00000182481 "Karyopherin subunit alpha 2" P52292 17 68035636-68047364 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 209.1" "Cell type enhanced" "Detected in all" "Early spermatids: 863.9;Extravillous trophoblasts: 279.7;Spermatocytes: 552.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015460, HPA041270" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes 160000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015460: AB_831493, HPA041270: AB_2677385" "unprognostic (2.78e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.14e-2)" "unprognostic (1.64e-1)" "unprognostic (5.16e-3)" "prognostic unfavorable (2.12e-10)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.34e-2)" "unprognostic (7.59e-2)" "unprognostic (3.72e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (1.26e-13)" "unprognostic (3.07e-2)" "unprognostic (1.78e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (2.19e-4)" 25.9 15.9 18.9 45.2 19.3 99.2 15.2 18.7 23.3 17.4 15.7 30.7 26.1 17.6 25.7 41.4 10.8 19.4 23.9 20.8 24.7 16.2 23.1 17.9 72.1 19.1 20.5 6.5 10.0 10.6 15.6 43.8 22.2 8.2 35.8 22.2 15.4 11.6 14.8 21.0 23.3 34.6 20.5 28.3 19.0 209.1 20.0 94.7 10.9 16.7 104.9 38.6 17.7 22.7 556.0 712.3 667.1 264.4 95.7 93.9 421.1 467.9 372.9 758.1 587.9 499.5 250.4 514.4 146.7 273.4 375.1 297.4 753.8 359.4 870.7 203.8 437.5 446.5 311.7 482.7 101.9 387.6 294.3 58.1 69.3 426.0 267.2 105.8 746.8 211.0 360.8 346.0 686.1 517.3 484.4 249.8 451.4 455.2 365.8 271.5 605.1 280.6 304.0 250.0 262.2 286.3 269.5 839.1 291.9 609.6 495.6 196.9 288.6 416.7 506.2 290.6 647.3 291.5 451.9 504.7 203.0 334.9 458.0 30.1 31.0 12.7 24.1 46.5 19.2 45.8 18.8 27.3 56.2 39.6 13.3 21.5 0.9 43.9 39.6 41.4 37.7 31.3 18.9 19.3 18.7 23.3 20.8 24.7 19.1 20.5 22.2 20.5 20.0 22.7 41.0 12.8 31.0 6.2 49.4 109.7 32.2 73.7 43.3 20.1 39.8 45.5 13.8 7.2 39.7 18.4 8.4 128.3 96.4 27.7 15.6 31.4 863.9 70.8 55.1 48.6 42.9 70.9 8.5 25.5 279.7 64.9 31.1 68.0 44.4 68.2 21.8 17.2 126.0 32.0 7.3 27.6 97.6 42.9 132.1 266.6 19.3 60.0 53.4 3.7 72.1 31.2 18.6 6.6 5.9 20.7 11.9 14.7 60.3 27.6 9.3 31.2 22.7 20.0 32.9 52.4 74.1 552.9 185.2 61.3 88.5 118.9 79.8 28.0 49.3 24.2 LIG1 ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: AB_2677476, HPA048071: AB_2680248" "unprognostic (1.83e-1)" "unprognostic (1.48e-3)" "unprognostic (6.45e-2)" "unprognostic (9.76e-2)" "unprognostic (9.47e-2)" "unprognostic (9.24e-3)" "unprognostic (1.17e-3)" "unprognostic (2.28e-1)" "unprognostic (6.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.78e-2)" "unprognostic (1.10e-3)" "prognostic unfavorable (5.75e-5)" "unprognostic (3.59e-2)" "unprognostic (4.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" 2.8 3.2 3.3 9.0 3.2 34.5 3.6 3.6 3.5 5.5 2.3 6.8 8.6 4.0 2.5 7.4 5.9 2.3 1.6 2.9 3.2 2.9 4.0 3.4 15.6 4.4 2.9 6.0 7.0 4.2 4.8 5.1 4.5 4.0 4.2 2.7 4.8 3.0 3.8 10.4 9.6 2.2 2.6 6.0 5.2 8.2 3.1 20.7 5.1 1.0 9.7 3.5 5.0 3.9 43.4 64.1 57.1 37.6 2.6 4.2 41.7 27.0 19.1 44.1 47.2 35.0 42.9 83.7 15.3 11.2 11.9 30.1 24.7 26.7 16.9 45.2 48.8 56.4 38.7 47.5 1.0 63.0 43.7 5.7 2.5 23.0 3.4 5.0 24.0 51.0 46.3 29.8 23.3 44.0 107.3 123.7 33.6 46.7 15.9 84.1 48.4 43.6 12.3 64.8 36.3 36.5 32.3 33.6 10.1 12.5 22.7 44.5 22.6 31.7 54.3 23.9 40.3 29.3 49.0 83.1 12.7 38.0 33.3 0.0 1.6 2.6 7.8 6.8 7.7 10.9 8.8 8.3 1.6 10.0 11.5 8.2 1.3 12.1 3.3 1.5 10.9 5.7 3.3 3.2 3.6 3.5 2.9 3.2 4.4 2.9 4.5 2.6 3.1 3.9 3.9 3.2 13.6 5.9 16.1 8.3 9.5 8.7 24.5 21.5 7.8 12.3 3.9 7.2 10.3 3.7 10.4 31.1 9.6 10.2 7.9 5.8 19.3 12.0 5.1 8.3 0.0 36.2 4.2 5.2 35.8 6.8 5.1 8.3 6.3 23.1 5.0 5.3 16.4 8.4 5.6 10.0 6.1 3.5 6.8 8.5 2.1 6.6 3.6 3.7 7.2 10.9 11.3 3.5 8.4 3.0 4.4 1.9 23.0 2.8 7.6 4.7 19.5 11.3 13.1 4.5 6.5 13.5 26.1 15.9 9.1 10.0 13.9 6.0 15.3 8.7 LIN9 TGS ENSG00000183814 "Lin-9 DREAM MuvB core complex component" Q5TKA1 1 226231149-226309869 "Predicted intracellular proteins" "Cell cycle, DNA synthesis" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 20.2;Spermatocytes: 36.3;Spermatogonia: 18.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030241 Uncertain Supported Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA030241: AB_10601542" "unprognostic (9.90e-2)" "unprognostic (8.00e-2)" "unprognostic (1.23e-1)" "unprognostic (8.82e-3)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" "unprognostic (3.51e-5)" "unprognostic (2.80e-2)" "unprognostic (9.84e-3)" "unprognostic (2.65e-2)" "unprognostic (3.59e-3)" "unprognostic (1.17e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-2)" "unprognostic (1.79e-1)" "unprognostic (3.22e-1)" "unprognostic (8.26e-2)" 1.8 1.6 0.9 2.8 1.0 6.6 3.5 3.5 1.6 1.8 0.6 3.2 4.1 3.2 1.6 3.2 2.4 1.5 12.8 0.9 0.7 2.1 1.4 2.5 5.0 0.6 0.8 5.0 2.0 2.2 0.6 4.0 0.7 2.1 3.9 1.8 2.0 1.9 3.6 3.4 3.9 2.8 0.7 2.6 3.0 9.7 0.7 8.1 2.2 3.5 4.8 1.9 1.7 1.1 15.9 10.0 16.2 11.6 1.5 3.8 31.2 11.4 7.3 20.2 18.1 10.8 20.0 15.0 14.1 5.3 8.9 14.4 15.9 6.1 18.0 14.4 28.1 9.4 12.2 7.7 1.4 18.6 9.7 1.5 4.3 10.5 10.6 4.9 10.0 13.7 33.5 17.8 12.3 5.8 19.5 12.0 26.0 20.1 18.2 18.7 27.5 19.4 6.6 8.2 14.2 19.9 20.3 23.6 14.7 10.0 13.4 23.8 4.8 11.4 16.3 15.7 29.4 8.2 20.2 31.0 6.6 16.7 27.2 4.1 1.0 1.1 1.2 1.3 1.9 2.2 1.9 2.7 0.5 1.6 3.4 2.6 0.2 1.7 2.8 0.6 2.8 1.0 0.9 1.0 3.5 1.6 0.9 0.7 0.6 0.8 0.7 0.7 0.7 1.1 3.1 9.6 5.1 3.3 3.3 3.3 1.4 2.8 3.4 1.2 2.1 2.2 15.7 1.5 2.2 0.0 0.0 13.0 2.8 1.6 1.9 2.3 20.2 2.0 3.4 3.1 2.4 16.4 11.1 3.3 6.9 3.3 2.0 1.6 1.3 4.3 2.2 1.4 2.8 3.3 8.7 2.5 0.0 3.5 1.1 4.0 4.4 1.9 0.0 6.5 0.4 1.9 2.1 10.1 4.7 2.8 3.8 4.5 6.4 1.2 2.0 1.7 3.7 1.0 0.0 3.0 4.5 36.3 18.7 5.1 1.8 15.5 2.8 1.9 4.9 1.5 LMNB1 ENSG00000113368 "Lamin B1" P20700 5 126776623-126837020 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.0;lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Early spermatids: 92.5;Erythroid cells: 67.3;Extravillous trophoblasts: 68.2;granulocytes: 93.6;Late spermatids: 72.1;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005269, HPA050524, CAB079757, CAB079954" Supported Supported "Nuclear membrane" NA NA 2100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB005269: AB_648156, CAB079757: AB_2665863, CAB079954: , HPA050524: AB_2681156" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" "unprognostic (4.96e-3)" "unprognostic (3.70e-2)" "unprognostic (1.61e-1)" "unprognostic (8.65e-3)" "prognostic unfavorable (3.08e-6)" "unprognostic (2.06e-2)" "unprognostic (6.62e-3)" "unprognostic (5.28e-2)" "unprognostic (2.13e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.33e-2)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" 4.2 1.6 1.9 26.6 1.8 34.0 2.9 9.8 2.1 3.7 0.5 14.9 11.2 2.8 0.5 14.2 1.8 3.4 1.5 1.6 3.3 3.5 4.9 6.0 34.8 2.9 2.3 2.2 2.4 0.7 2.0 6.7 2.4 1.6 13.0 6.4 3.4 1.6 1.0 8.6 14.2 3.5 2.1 13.3 7.9 2.2 2.3 49.2 1.6 1.4 29.2 6.8 4.8 1.8 132.7 43.4 131.6 126.6 3.3 9.3 170.6 60.6 17.8 66.1 71.3 113.4 107.2 229.4 103.2 21.4 31.5 72.4 90.9 42.1 72.2 162.9 112.1 147.5 49.1 67.2 1.4 176.6 95.6 3.0 0.9 35.2 16.0 12.8 54.9 92.0 87.1 86.3 46.6 109.7 322.8 347.5 99.0 54.1 60.0 152.6 259.4 93.1 36.6 59.6 151.4 80.3 98.4 41.7 36.6 45.2 76.2 202.0 46.9 48.7 132.0 36.6 131.3 56.8 46.4 197.3 25.0 247.1 73.8 1.4 14.4 4.8 2.1 5.6 1.6 4.2 4.3 2.8 15.3 2.9 3.1 2.8 9.3 2.4 1.5 4.6 12.4 6.4 1.9 1.8 9.8 2.1 1.6 3.3 2.9 2.3 2.4 2.1 2.3 1.8 3.4 0.0 4.3 0.3 20.1 5.0 1.9 2.0 8.0 6.4 4.3 5.1 1.6 4.3 3.3 0.0 8.4 39.4 56.0 7.7 1.9 1.8 92.5 3.9 4.8 8.8 6.1 67.3 6.8 0.8 68.2 8.1 11.7 7.6 93.6 23.9 3.6 3.1 21.8 5.0 9.1 19.3 0.0 13.1 17.9 72.1 2.1 27.9 1.8 1.9 59.5 3.8 13.4 5.5 1.1 1.1 8.4 0.4 50.6 1.1 3.8 2.1 1.9 17.5 0.0 2.5 7.3 3.4 8.9 27.3 5.4 4.7 34.2 3.0 35.8 1.4 LSM2 "C6orf28, G7b, YBL026W" ENSG00000204392 "LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y333 6 31797396-31806966 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052805, HPA066718" Supported Enhanced Nucleoplasm NA NA 97000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA052805: , HPA066718: AB_2685710" "unprognostic (1.69e-1)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "unprognostic (1.24e-1)" "unprognostic (5.10e-2)" "unprognostic (1.50e-1)" "unprognostic (1.36e-3)" "unprognostic (6.14e-2)" "unprognostic (1.03e-1)" "unprognostic (2.34e-3)" "unprognostic (1.51e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.59e-9)" "unprognostic (2.23e-1)" "unprognostic (8.48e-2)" "unprognostic (4.49e-2)" "unprognostic (9.59e-2)" 38.6 34.3 19.0 19.3 21.8 32.7 37.9 20.6 21.4 44.8 17.4 43.0 23.6 45.0 19.3 39.0 36.9 18.1 32.3 19.4 19.1 43.8 27.6 31.6 36.6 22.8 19.6 37.6 37.2 20.5 30.1 22.5 21.7 29.7 27.8 7.2 25.2 16.3 43.9 37.0 33.6 27.7 24.5 43.5 34.6 26.7 22.9 45.1 30.1 20.9 39.3 39.9 35.6 23.7 91.1 42.5 84.9 103.7 43.8 61.9 58.4 50.1 38.5 85.2 75.1 56.9 37.6 50.3 66.8 50.1 79.8 36.2 109.3 101.1 76.9 72.4 85.0 83.6 27.3 60.1 55.7 80.6 39.7 47.1 47.3 78.6 80.4 40.6 90.3 102.0 127.5 63.0 60.7 73.3 132.3 168.4 56.8 75.0 77.6 73.4 40.5 123.4 69.5 31.6 66.6 55.6 56.0 58.8 101.7 44.7 61.6 68.7 20.1 47.6 74.5 54.1 85.1 53.2 109.9 88.2 26.8 123.3 76.7 29.1 31.3 15.9 36.9 37.7 45.2 3.7 51.6 33.6 35.4 4.1 45.6 30.1 8.7 13.8 25.1 30.9 29.9 57.5 19.0 21.8 20.6 21.4 19.4 19.1 22.8 19.6 21.7 24.5 22.9 23.7 82.9 22.4 23.6 4.6 95.2 58.2 63.7 104.9 56.3 30.9 108.2 177.2 14.9 60.1 48.5 55.2 6.2 143.5 58.5 36.5 113.5 104.5 20.1 38.8 61.2 90.2 54.0 121.8 5.9 137.1 218.8 58.0 46.9 49.2 82.6 119.9 72.8 59.7 143.2 30.3 6.0 93.9 73.2 67.9 76.8 26.0 49.7 56.6 92.5 3.7 99.3 53.3 109.2 9.5 19.8 94.0 55.7 49.2 91.5 78.2 40.8 113.3 24.2 28.3 46.0 70.7 71.4 66.9 176.5 90.8 64.2 69.0 77.8 101.3 113.6 58.6 LSM4 YER112W ENSG00000130520 "LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Z0 19 18306236-18323112 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 705.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040932 Uncertain Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA040932: AB_10795529" "unprognostic (2.71e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (7.42e-3)" "unprognostic (1.98e-1)" "unprognostic (4.09e-2)" "unprognostic (1.10e-3)" "unprognostic (9.80e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.34e-4)" "unprognostic (8.31e-3)" "unprognostic (1.25e-1)" "prognostic favorable (2.22e-4)" "unprognostic (2.51e-2)" "unprognostic (7.23e-2)" "unprognostic (8.08e-2)" "unprognostic (1.34e-1)" 56.5 130.5 97.9 31.8 101.8 62.9 55.1 99.7 111.7 52.7 111.4 86.4 57.6 51.6 36.3 100.5 52.8 17.4 108.2 102.8 104.9 118.8 122.8 60.9 41.4 99.6 102.5 50.6 57.4 48.5 72.5 35.5 105.1 64.2 45.2 33.1 55.2 39.6 149.1 70.4 77.1 27.3 95.9 71.1 78.4 126.8 104.8 78.9 62.2 89.4 38.9 62.1 59.7 97.3 294.3 151.2 252.3 226.2 95.4 91.4 291.8 132.2 113.6 167.9 158.7 137.0 305.5 172.0 274.5 139.0 152.5 192.3 276.4 274.5 127.1 201.1 524.0 156.1 247.0 167.5 94.9 148.9 89.2 83.3 160.5 156.9 182.9 94.2 139.6 248.6 333.0 172.3 177.3 479.7 411.0 321.6 327.1 419.2 475.4 229.4 112.0 320.5 212.9 102.0 283.8 264.9 113.0 141.3 204.2 174.8 140.4 157.8 81.0 98.0 113.2 244.3 250.5 160.2 147.7 204.4 131.4 289.3 170.4 171.5 223.2 163.8 148.3 258.5 182.5 163.5 158.3 154.4 252.8 164.5 169.7 171.4 18.4 220.4 205.6 359.0 166.9 283.9 97.9 101.8 99.7 111.7 102.8 104.9 99.6 102.5 105.1 95.9 104.8 97.3 76.8 28.9 38.8 7.5 85.1 67.4 92.4 183.1 46.7 72.0 141.7 134.9 53.2 74.4 90.5 115.8 14.6 270.4 95.8 179.1 299.3 196.7 280.8 102.8 55.1 75.7 124.4 109.8 11.5 182.1 489.1 67.9 68.8 96.9 117.4 115.7 54.3 89.3 288.4 58.9 11.1 194.5 154.6 85.4 129.0 705.7 62.4 109.1 104.9 7.5 243.2 115.6 130.7 7.1 13.4 159.3 205.5 47.4 98.3 153.1 225.3 347.7 94.6 73.0 46.0 38.5 80.7 203.1 378.6 125.5 71.9 170.5 87.7 174.2 237.1 119.9 LSM5 YER146W ENSG00000106355 "LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Y9 7 32485338-32495283 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019054 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA019054: AB_10960217" "unprognostic (1.92e-1)" "unprognostic (5.36e-2)" "unprognostic (3.23e-2)" "unprognostic (1.51e-1)" "unprognostic (8.92e-2)" "unprognostic (3.51e-2)" "prognostic unfavorable (7.53e-5)" "unprognostic (2.22e-1)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (1.84e-4)" "unprognostic (3.08e-1)" "unprognostic (3.89e-2)" "unprognostic (2.53e-2)" "unprognostic (1.18e-1)" 35.8 41.9 26.2 35.8 27.0 77.6 62.6 27.0 40.3 33.7 25.4 58.1 42.4 34.0 35.5 46.6 34.5 28.1 50.1 26.2 26.9 46.8 76.0 28.1 61.7 26.0 26.6 36.4 54.7 30.0 29.1 28.8 26.5 34.3 60.0 28.8 31.4 27.8 57.6 33.8 39.4 36.5 26.7 41.0 47.0 22.5 26.3 67.9 44.4 51.1 72.2 37.6 34.4 27.0 204.6 121.9 162.8 229.4 56.0 62.2 80.9 94.9 79.9 119.3 125.6 168.9 170.0 118.8 49.0 67.7 290.9 119.1 121.1 118.7 161.2 84.6 132.7 124.6 193.5 233.7 49.6 267.4 123.3 52.4 85.1 116.7 137.4 79.2 132.9 203.4 261.0 90.5 169.2 246.3 140.3 598.9 267.9 296.7 139.4 122.3 128.4 200.9 107.3 97.8 140.5 206.4 84.9 237.0 114.6 243.5 148.4 331.6 63.9 102.5 252.6 95.8 246.2 149.2 339.9 354.5 96.9 314.9 296.6 17.9 35.0 34.2 38.6 57.4 58.2 69.2 62.9 50.7 50.7 60.2 89.3 68.9 6.0 44.9 49.5 100.1 57.4 45.2 26.2 27.0 27.0 40.3 26.2 26.9 26.0 26.6 26.5 26.7 26.3 27.0 68.9 32.1 50.6 13.7 135.3 146.4 152.0 254.1 109.8 52.5 201.8 262.4 109.7 94.4 116.7 114.0 22.9 211.9 93.4 95.6 277.8 137.0 16.1 91.1 68.2 81.0 50.5 184.5 15.9 216.6 286.2 98.8 98.8 74.6 72.2 148.2 79.6 285.6 189.8 43.7 20.4 164.9 175.0 117.9 158.2 21.2 75.8 100.1 122.7 13.1 163.9 94.3 78.2 10.1 13.9 146.3 118.2 82.4 187.0 146.9 107.6 343.4 137.5 59.7 65.7 81.9 141.9 88.5 133.2 167.7 177.6 100.6 111.8 123.2 233.2 152.8 MAD2L1 "HSMAD2, MAD2" ENSG00000164109 "Mitotic arrest deficient 2 like 1" Q13257 4 120055623-120066858 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.9;lymphoid tissue: 5.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.8;Extravillous trophoblasts: 119.2;Spermatocytes: 127.8;Spermatogonia: 76.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003348 Uncertain Approved Nucleoplasm NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA003348: AB_10603014" "unprognostic (4.08e-3)" "unprognostic (7.31e-2)" "unprognostic (5.17e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (5.15e-5)" "prognostic unfavorable (2.17e-4)" "unprognostic (6.74e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "unprognostic (3.87e-3)" "prognostic unfavorable (3.07e-11)" "unprognostic (3.06e-2)" "unprognostic (4.05e-1)" "unprognostic (1.03e-1)" "unprognostic (9.70e-2)" 0.3 0.4 0.5 2.1 0.6 5.9 1.2 0.8 0.7 0.5 0.2 2.2 1.8 0.7 0.3 1.6 1.4 0.4 0.5 0.5 0.5 0.4 0.5 0.4 4.0 0.4 0.4 0.5 0.2 0.4 0.1 1.4 0.5 0.6 2.6 1.0 0.3 0.5 0.2 1.0 1.9 0.8 0.4 0.8 0.9 2.3 0.4 5.7 0.4 0.2 3.6 0.7 0.5 0.6 27.2 11.6 26.9 17.5 2.8 3.4 11.5 21.0 11.8 21.5 16.5 15.7 16.3 39.6 6.8 7.6 9.5 7.1 27.1 16.1 30.0 18.8 18.8 22.0 10.5 14.9 0.8 36.3 12.0 1.9 2.3 14.6 9.1 5.4 12.6 16.4 26.7 22.0 11.4 12.0 35.0 15.6 18.3 14.1 13.0 17.8 35.9 16.2 8.7 10.3 28.4 20.1 10.5 12.8 6.5 12.9 8.4 13.0 7.8 14.2 16.1 14.6 27.0 20.1 23.2 25.7 13.3 18.4 19.1 0.9 0.1 0.1 0.4 0.1 0.6 0.5 1.2 1.0 0.1 0.4 1.1 1.1 0.3 0.9 0.2 0.7 1.3 0.5 0.5 0.6 0.8 0.7 0.5 0.5 0.4 0.4 0.5 0.4 0.4 0.6 2.4 0.0 1.3 1.0 11.5 17.3 7.3 23.5 4.0 9.7 7.2 8.3 3.4 1.5 6.0 7.3 2.1 52.0 7.6 7.5 0.0 3.4 2.4 31.3 6.0 5.4 1.8 81.8 1.3 1.5 119.2 13.7 8.6 7.8 15.2 34.6 3.9 2.9 27.9 20.2 1.2 13.7 36.7 7.3 13.4 4.8 4.7 6.1 8.8 0.0 3.1 12.3 5.2 0.5 1.0 1.6 3.7 1.5 33.1 5.0 3.7 7.2 12.9 3.8 13.1 7.3 14.9 127.8 76.2 26.0 8.9 10.8 20.1 11.9 29.2 8.7 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27187953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027175: AB_1853591, HPA054273: AB_2682433" "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 5.0 3.9 1.7 6.2 1.9 18.7 5.3 2.3 2.3 3.8 2.1 4.1 4.4 3.9 4.5 5.9 3.0 3.9 2.5 1.9 2.0 3.9 4.9 4.0 8.9 2.0 2.0 3.4 3.3 6.0 3.1 6.5 2.1 3.1 5.2 2.7 4.1 3.0 2.3 6.0 4.3 4.5 1.6 4.6 4.7 6.5 2.0 10.4 4.7 2.2 7.1 4.5 4.3 2.3 29.4 22.0 43.8 15.5 6.2 9.1 25.4 43.3 18.0 68.4 83.8 26.7 27.2 22.4 16.1 18.4 33.5 26.8 27.9 16.0 48.2 20.2 26.5 26.9 14.5 15.5 3.8 10.4 19.8 5.6 7.5 41.6 7.9 9.0 14.7 18.2 21.1 49.9 41.5 17.9 34.8 11.2 32.0 15.9 8.9 22.2 71.9 18.9 17.4 10.6 19.2 26.8 26.0 17.6 19.1 28.1 17.2 21.4 12.6 17.0 36.3 44.0 37.4 5.9 10.3 34.7 18.3 31.1 14.8 0.2 1.8 1.7 0.7 1.7 1.1 1.1 0.9 0.7 1.0 1.6 0.9 0.8 2.3 1.0 1.8 1.1 1.6 0.8 1.7 1.9 2.3 2.3 1.9 2.0 2.0 2.0 2.1 1.6 2.0 2.3 4.3 6.4 7.8 2.6 7.4 11.0 4.9 4.4 4.0 1.7 4.2 4.8 3.0 2.8 7.0 1.8 0.0 8.6 10.1 7.0 0.0 4.0 3.0 9.7 5.3 4.6 4.2 7.8 4.3 2.5 24.9 7.3 6.1 17.9 12.7 6.9 2.5 2.5 5.8 3.3 4.3 3.7 4.1 7.8 19.3 1.7 3.1 11.3 0.0 3.7 5.1 1.8 3.1 3.5 4.9 4.4 2.9 2.6 7.1 5.0 2.8 1.9 4.0 1.0 0.0 3.8 5.3 14.9 14.1 10.9 9.9 6.2 11.6 5.4 4.5 6.6 MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161558-13211110 "Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.2;lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.8;Erythroid cells: 23.5;Extravillous trophoblasts: 20.9;Plasma cells: 15.3;Spermatocytes: 15.8;Spermatogonia: 12.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA045899: AB_10960529, HPA071952: AB_2686477" "unprognostic (9.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-3)" "unprognostic (1.41e-1)" "unprognostic (6.58e-3)" "unprognostic (1.78e-8)" "unprognostic (2.42e-3)" "unprognostic (3.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.78e-4)" "unprognostic (7.81e-2)" "unprognostic (0.00e+0)" "unprognostic (8.87e-2)" "unprognostic (1.29e-1)" "unprognostic (9.73e-2)" "unprognostic (1.05e-1)" 1.2 0.1 0.0 3.3 0.1 9.2 0.8 0.1 0.2 0.4 0.1 1.7 1.5 0.4 0.1 1.9 0.2 0.2 0.1 0.0 0.0 0.1 0.7 0.3 4.8 0.0 0.1 0.2 0.1 0.2 0.1 2.1 0.1 0.1 2.2 0.1 0.3 0.0 0.5 1.1 1.2 0.8 0.0 1.0 0.8 1.5 0.2 8.1 0.3 0.1 4.5 0.6 0.6 0.1 38.0 42.0 48.6 36.9 1.6 2.9 21.2 38.7 5.9 42.7 44.0 41.3 26.4 56.7 17.1 9.9 15.7 43.3 69.0 22.8 39.2 29.7 32.9 70.9 17.6 27.7 0.0 36.6 30.8 0.6 0.8 43.3 4.0 3.5 14.0 45.0 85.2 37.6 23.4 34.0 87.7 15.7 28.9 36.3 10.3 68.3 43.0 34.6 9.8 13.7 9.7 36.6 31.3 22.0 5.9 25.2 27.7 24.9 8.6 27.0 50.3 41.0 42.4 11.7 49.0 74.3 17.2 39.6 21.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.9 0.3 0.1 0.1 0.7 0.4 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 1.7 0.0 0.0 0.0 1.8 1.7 0.4 0.8 0.0 0.0 0.8 0.5 2.4 0.0 0.8 0.0 0.0 11.8 0.8 2.4 0.0 0.4 1.0 0.3 1.2 1.4 0.0 23.5 0.4 0.2 20.9 1.8 1.1 1.0 0.0 7.2 0.0 0.2 5.3 0.0 0.4 1.2 2.0 0.6 0.4 1.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.1 0.4 15.3 0.2 0.2 0.0 0.0 0.0 0.0 0.4 6.4 15.8 12.9 3.6 0.4 3.4 1.2 0.8 3.1 0.4 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.7;lymphoid tissue: 37.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.3;Erythroid cells: 65.6;Extravillous trophoblasts: 28.8;Spermatogonia: 25.9;Syncytiotrophoblasts: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 3.1 3.4 2.0 16.4 1.9 67.7 6.2 2.5 1.9 5.3 0.6 9.2 8.1 5.0 2.4 11.0 7.6 2.5 6.4 1.9 1.8 3.4 6.3 3.4 26.8 2.3 1.9 6.4 3.0 3.7 2.4 17.0 2.6 5.0 10.2 3.5 4.7 2.8 9.4 10.6 8.6 5.3 2.0 9.6 5.7 12.3 2.0 37.6 4.8 5.8 26.0 4.2 5.4 2.4 133.6 110.3 122.4 102.1 7.0 14.4 110.5 65.2 42.3 129.9 146.9 177.7 84.7 136.0 65.2 32.3 113.6 105.6 204.8 76.1 79.1 127.2 127.1 227.4 134.8 131.1 4.4 214.3 102.4 8.2 8.4 86.1 13.1 15.3 40.6 160.7 116.0 123.7 47.4 169.0 229.0 156.2 172.5 108.3 90.7 242.4 165.1 203.3 26.9 97.9 143.0 106.8 175.8 48.9 16.7 45.7 111.9 165.3 20.3 104.2 87.9 128.4 91.7 127.1 163.5 362.6 73.2 159.7 41.0 0.0 0.6 0.3 4.4 1.4 5.5 9.7 3.9 5.4 2.9 8.1 3.6 4.7 0.9 6.5 0.4 3.7 11.2 3.5 2.0 1.9 2.5 1.9 1.9 1.8 2.3 1.9 2.6 2.0 2.0 2.4 1.2 3.2 2.0 0.7 8.5 4.6 2.6 4.6 2.2 2.5 4.1 5.3 8.3 0.0 3.9 0.0 0.0 63.3 1.8 4.8 0.0 5.3 0.9 5.2 3.5 2.9 3.6 65.6 0.3 1.9 28.8 4.2 6.6 4.8 1.3 18.8 1.4 1.7 18.2 0.0 0.4 8.2 0.0 1.6 3.2 0.7 1.8 2.7 1.8 0.0 9.2 2.1 0.0 0.0 0.7 2.1 1.7 1.5 20.5 0.8 1.1 0.8 7.4 2.1 0.0 2.6 4.1 8.1 25.9 7.1 3.0 33.5 6.3 3.8 13.8 2.3 MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264014-52284881 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 122.7;Erythroid cells: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002162, HPA004789, HPA004790" Supported Supported Nucleoplasm NA Yes 150000 "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB002162: AB_564115, HPA004789: AB_1079336, HPA004790: AB_1079335" "unprognostic (9.14e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.37e-1)" "unprognostic (1.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.15e-1)" "unprognostic (8.35e-2)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.34e-2)" 24.3 15.9 12.8 41.5 13.6 55.5 29.1 13.7 13.7 27.5 13.4 32.9 19.6 30.8 23.8 33.4 29.2 16.4 25.4 11.9 12.7 27.5 18.8 21.4 68.8 14.1 13.6 31.9 17.0 28.9 10.8 40.0 14.1 19.7 39.3 19.3 19.2 30.7 16.0 32.2 29.3 37.0 14.5 31.3 24.1 21.1 14.0 81.1 18.3 17.7 78.5 28.1 24.5 13.9 187.9 121.7 208.0 196.9 43.9 39.4 136.1 135.8 103.7 226.6 230.3 251.6 99.2 202.8 132.5 79.7 147.8 145.4 277.4 165.9 226.9 230.0 261.4 383.6 233.2 358.2 11.8 381.7 150.8 23.7 38.1 166.6 46.2 55.6 117.3 240.4 318.1 452.9 118.3 123.8 386.9 293.5 173.1 369.8 84.8 338.3 317.0 271.2 101.1 195.8 210.3 160.5 142.2 81.1 125.3 289.4 159.7 266.9 60.5 153.5 163.6 160.8 206.4 132.9 163.5 356.4 132.2 323.8 184.0 30.5 18.3 27.3 50.0 31.3 42.8 47.7 49.9 50.3 30.0 41.2 47.6 51.2 2.6 55.0 18.3 19.0 71.6 46.9 12.8 13.6 13.7 13.7 11.9 12.7 14.1 13.6 14.1 14.5 14.0 13.9 24.3 22.4 12.3 3.3 26.4 19.2 20.0 24.9 12.5 16.1 14.1 17.1 19.9 7.2 19.2 22.0 4.2 122.7 18.6 10.9 13.7 30.9 1.1 9.6 16.7 30.9 7.3 92.6 2.5 20.2 63.6 22.3 15.8 15.1 37.4 48.3 15.0 10.5 36.0 0.0 2.1 20.4 8.2 10.1 7.5 3.6 27.1 12.1 7.2 8.4 12.5 17.8 34.0 2.5 6.1 17.3 10.5 21.1 37.6 10.9 7.3 7.5 17.0 16.0 6.6 16.8 27.9 22.5 64.0 24.5 10.1 27.4 26.0 19.0 37.1 13.9 MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2" "Cell type enhanced" "Detected in many" "Early spermatids: 153.2;Erythroid cells: 60.8;Late spermatids: 77.9;Spermatocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004497: AB_627916, HPA004873: AB_1079337, HPA031052: AB_2673712" "unprognostic (4.55e-2)" "unprognostic (3.16e-3)" "prognostic favorable (2.19e-4)" "prognostic unfavorable (2.84e-5)" "unprognostic (7.71e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (2.65e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.70e-2)" "unprognostic (1.40e-1)" 6.5 8.8 4.8 21.7 4.8 63.2 16.0 5.7 5.2 7.7 1.8 17.7 13.3 6.9 4.6 22.4 9.7 5.6 14.5 5.2 3.5 8.2 9.2 6.3 38.7 3.6 4.2 7.1 5.5 7.7 4.1 18.3 3.9 5.6 21.3 12.3 8.8 4.9 13.4 24.2 16.7 9.2 4.2 8.1 10.6 41.6 4.8 47.0 6.5 15.8 41.8 11.8 10.9 5.2 184.0 139.6 188.1 83.2 20.7 36.6 102.8 122.6 99.8 178.5 190.3 156.6 181.1 229.8 70.3 72.1 119.2 143.2 278.7 128.2 199.8 64.2 190.4 371.8 133.3 169.2 5.4 189.7 82.0 20.3 24.1 147.8 54.3 28.6 72.0 136.8 216.2 167.0 129.9 155.6 435.5 141.5 241.2 246.5 54.2 266.6 159.6 139.2 64.9 168.1 209.0 97.8 325.6 133.6 46.3 117.7 154.9 110.5 45.1 138.1 125.4 144.5 131.9 54.7 104.6 347.2 114.8 185.7 131.5 2.3 1.8 1.1 4.0 3.1 2.0 3.9 3.8 5.4 3.9 1.6 3.3 2.7 0.1 4.1 3.5 1.5 10.2 3.6 4.8 4.8 5.7 5.2 5.2 3.5 3.6 4.2 3.9 4.2 4.8 5.2 3.3 0.0 6.3 3.3 6.5 21.7 11.1 9.0 13.6 12.2 9.0 7.7 25.1 1.5 8.4 5.5 10.4 36.7 5.8 12.1 3.9 8.0 153.2 11.0 7.9 6.7 6.7 60.8 5.0 6.0 40.2 10.6 11.2 13.4 1.3 24.9 2.2 3.2 12.3 16.8 5.7 13.9 4.1 2.9 6.5 77.9 5.3 7.9 3.6 1.9 2.4 7.0 3.1 4.0 2.9 4.5 4.8 3.0 22.3 7.7 5.6 3.0 13.1 16.7 0.0 9.5 11.4 65.8 39.9 19.1 19.0 29.8 9.0 11.7 26.2 9.7 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.8;Erythroid cells: 96.6;monocytes: 137.7;Syncytiotrophoblasts: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 44000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 15.2 7.1 5.8 49.1 10.4 138.7 14.4 8.3 7.4 14.5 5.8 20.2 19.6 16.3 3.3 25.1 13.7 9.6 8.9 5.8 7.0 9.1 14.9 14.8 70.1 10.3 7.7 25.6 12.6 10.3 5.3 25.2 9.6 10.2 16.7 2.3 13.9 9.6 13.3 17.6 28.3 12.2 8.1 47.3 17.9 20.6 9.0 58.9 12.1 8.0 53.6 12.7 15.6 12.3 213.0 147.5 115.7 118.8 11.0 22.2 100.6 138.1 71.2 199.4 188.3 98.9 102.4 137.9 78.8 70.5 83.6 103.8 116.0 108.3 64.4 112.7 212.6 198.3 141.5 203.7 3.9 414.0 172.4 12.3 9.7 120.0 32.4 18.4 88.7 124.5 124.0 201.2 76.9 172.7 341.8 137.9 154.9 143.4 86.7 379.6 164.8 173.0 39.4 120.1 88.2 94.8 188.3 75.4 41.8 60.9 78.8 155.6 54.1 201.3 153.1 127.2 145.4 111.9 150.2 265.2 130.9 153.5 157.6 66.5 59.8 43.4 49.5 69.6 35.8 127.5 43.1 53.1 77.8 106.1 34.0 39.0 28.4 65.5 81.2 88.8 96.6 77.1 5.8 10.4 8.3 7.4 5.8 7.0 10.3 7.7 9.6 8.1 9.0 12.3 8.1 6.4 7.3 1.3 49.5 10.6 13.6 12.1 8.6 1.5 9.2 10.8 3.5 8.6 6.0 7.3 0.0 147.8 30.4 12.0 5.9 19.8 2.8 6.2 4.1 11.8 3.5 96.6 0.3 12.7 77.1 11.2 18.8 9.0 15.2 65.7 13.2 5.3 53.1 1.7 0.4 16.6 4.1 24.0 29.4 5.1 10.8 28.4 7.2 7.5 137.7 5.7 13.4 3.0 6.0 11.0 8.6 6.0 49.3 4.0 6.5 5.7 4.8 3.7 19.7 8.8 14.5 16.1 58.8 14.9 6.3 82.2 19.4 8.5 34.6 9.8 MCM7 "CDC47, MCM2, PPP1R104" ENSG00000166508 "Minichromosome maintenance complex component 7" P33993 7 100092728-100101940 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 180.8;lymphoid tissue: 156.4" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 132.9;Erythroid cells: 173.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002163, HPA003898, CAB016312" Enhanced Enhanced Nucleoplasm NA Yes 150000 "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB002163: AB_564113, CAB016312: AB_627235, HPA003898: AB_1853632" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-4)" "unprognostic (1.36e-1)" "unprognostic (5.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (2.18e-4)" "unprognostic (2.08e-2)" "unprognostic (5.79e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (9.34e-3)" "unprognostic (3.83e-2)" "unprognostic (5.41e-2)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (2.38e-1)" 22.9 14.2 56.4 50.2 61.7 180.8 32.0 51.4 70.4 17.4 45.8 45.3 38.7 29.7 13.1 31.2 25.6 18.2 17.0 48.8 50.5 13.7 26.3 23.0 82.4 58.5 59.8 37.0 24.1 15.1 8.9 35.0 55.1 20.4 50.8 10.6 21.3 22.2 25.7 44.9 41.3 32.3 55.1 29.4 27.4 49.4 55.6 156.4 20.4 28.5 88.5 21.6 11.9 60.8 310.1 359.5 399.9 306.7 28.7 35.5 214.4 195.7 165.5 374.9 407.7 281.9 335.2 469.2 184.6 112.0 321.6 252.5 439.3 241.6 303.9 238.6 498.1 274.7 251.9 248.9 18.9 553.6 226.2 30.1 43.4 306.9 179.6 61.8 154.0 295.1 542.2 444.6 200.8 786.2 940.1 442.9 361.9 295.2 236.4 572.5 517.7 651.6 92.3 221.5 253.4 397.0 264.9 294.3 104.9 217.9 126.2 314.4 81.0 198.1 346.7 379.8 411.1 200.3 311.8 875.0 135.9 463.1 354.3 3.7 4.0 4.3 14.1 7.5 10.9 9.1 10.3 13.2 9.3 15.0 11.2 10.5 1.4 15.9 13.3 11.3 17.2 11.6 56.4 61.7 51.4 70.4 48.8 50.5 58.5 59.8 55.1 55.1 55.6 60.8 23.2 9.6 17.9 6.2 34.5 46.7 28.5 25.7 37.0 9.4 30.8 36.3 9.6 11.5 13.3 3.7 14.6 132.9 32.5 42.3 9.8 28.2 54.7 11.8 16.3 23.8 17.4 173.6 4.0 26.2 102.7 22.8 40.8 19.8 24.1 67.3 10.4 10.3 40.4 6.7 4.0 48.8 18.3 10.4 22.2 32.0 21.1 17.6 19.6 3.7 14.1 11.1 18.6 12.1 11.7 16.7 22.8 15.4 59.8 20.8 19.0 11.5 18.0 12.5 13.1 30.7 46.0 90.0 79.8 41.3 35.4 72.0 29.4 14.9 79.0 22.9 MCMBP "C10orf119, FLJ13081, MCM-BP" ENSG00000197771 "Minichromosome maintenance complex binding protein" Q9BTE3 10 119829404-119892556 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013792, HPA038481" Uncertain Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cell Junctions, Cytosol" "CAB013792: , HPA038481: AB_10794620" "unprognostic (1.26e-1)" "unprognostic (7.92e-2)" "unprognostic (4.62e-2)" "unprognostic (2.31e-2)" "unprognostic (1.72e-2)" "unprognostic (4.64e-2)" "unprognostic (1.31e-3)" "unprognostic (5.61e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (7.32e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.23e-2)" "unprognostic (8.24e-2)" "unprognostic (2.51e-1)" "unprognostic (4.87e-2)" 30.5 14.2 9.1 16.7 10.5 10.0 26.1 12.9 11.9 23.8 9.7 25.9 13.3 26.7 10.8 25.0 23.7 12.1 18.2 9.4 10.4 16.1 18.6 24.9 18.9 11.3 10.2 22.2 17.0 16.1 11.0 25.3 11.5 15.2 16.6 12.3 20.5 13.7 30.1 25.6 19.6 18.3 11.5 19.5 20.3 11.8 9.9 20.7 17.5 15.9 19.7 25.1 24.1 12.4 54.4 28.6 49.6 40.3 24.0 27.1 27.0 49.2 55.9 62.2 63.3 42.5 32.9 69.7 20.3 34.8 20.7 46.8 65.1 46.8 74.1 46.0 50.3 34.7 20.8 38.3 35.7 71.3 80.6 24.1 25.8 47.4 60.7 27.6 38.9 37.5 35.3 43.9 41.7 28.5 77.4 52.6 33.3 34.7 26.5 49.8 104.0 30.8 29.0 30.0 25.0 28.7 32.9 33.1 39.3 33.0 20.4 50.2 34.3 26.5 24.1 29.8 56.3 36.1 37.7 71.1 35.5 46.1 16.2 9.8 2.3 1.4 2.0 4.2 2.0 2.0 2.0 1.9 3.2 0.9 2.0 2.2 3.0 1.8 2.5 1.5 1.9 1.1 9.1 10.5 12.9 11.9 9.4 10.4 11.3 10.2 11.5 11.5 9.9 12.4 39.0 16.0 16.5 11.8 26.2 42.8 35.0 12.3 24.5 11.4 18.1 14.2 18.6 25.8 15.6 20.2 4.2 40.5 35.4 23.7 13.7 11.7 4.6 18.8 31.7 38.3 10.8 25.0 14.0 13.7 52.6 27.4 12.2 26.2 18.3 18.2 26.7 25.6 38.5 32.0 17.3 20.8 12.2 35.5 35.0 6.2 30.1 35.9 23.2 15.0 34.2 18.3 26.8 17.6 25.3 15.8 11.9 22.6 28.0 32.8 15.6 18.7 12.5 18.3 19.7 32.8 27.4 42.5 68.7 29.9 42.8 39.7 31.6 12.7 29.1 29.1 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 21.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.1;Erythroid cells: 15.2;Extravillous trophoblasts: 44.1;Spermatocytes: 23.2;Spermatogonia: 21.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.7" "Lineage enriched" "Detected in single" 4 "T-cells: 1.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017214 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 0.9 0.5 0.0 5.7 0.0 10.0 1.4 0.0 0.1 1.3 0.0 6.8 5.2 1.0 0.0 7.9 0.3 0.6 0.2 0.0 0.0 0.3 0.7 0.9 10.0 0.0 0.1 0.2 0.3 0.1 0.0 5.3 0.1 0.3 8.5 0.0 1.2 0.1 0.0 3.4 4.4 2.4 0.0 2.0 3.2 9.2 0.3 21.0 0.3 0.1 11.7 1.7 2.3 0.0 123.4 62.1 81.6 48.5 11.1 18.8 47.1 88.8 62.2 121.5 148.2 47.8 47.3 40.9 27.8 43.8 106.5 41.0 71.7 55.5 133.1 112.3 28.6 32.0 69.1 48.1 4.3 50.2 39.0 6.9 9.8 93.9 53.0 15.6 62.2 61.9 41.7 63.2 100.9 40.9 63.1 23.4 65.1 55.1 47.9 57.4 54.9 25.8 37.7 40.7 55.1 40.8 47.4 45.3 28.6 45.2 38.0 23.7 30.8 65.4 81.8 56.1 82.3 12.3 47.9 60.7 41.2 36.8 91.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.7 1.9 4.6 0.9 3.5 0.0 0.0 0.9 0.8 0.4 0.0 2.0 0.0 0.0 16.1 0.7 4.5 0.0 1.1 2.8 2.9 1.4 1.3 0.0 15.2 0.8 1.1 44.1 3.3 4.6 2.1 0.0 7.8 1.4 0.7 10.1 0.0 0.7 4.7 4.1 1.6 3.0 2.7 1.2 1.9 0.0 0.0 3.1 0.0 2.1 1.0 0.4 1.7 2.7 0.0 10.2 0.5 0.6 0.1 2.0 0.0 0.0 0.0 3.7 23.2 21.3 9.3 1.7 8.9 2.7 0.7 8.9 2.3 MIS18A "B28, C21orf45, C21orf46, FASP1, hMis18alpha" ENSG00000159055 "MIS18 kinetochore protein A" Q9NYP9 21 32268228-32279049 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 109.9;Spermatogonia: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA018286, HPA020585" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "HPA018286: AB_1845693, HPA020585: AB_1845694" "unprognostic (1.19e-1)" "unprognostic (1.55e-2)" "unprognostic (4.44e-2)" "unprognostic (1.98e-3)" "unprognostic (3.45e-2)" "unprognostic (2.29e-2)" "unprognostic (1.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.19e-2)" "unprognostic (4.39e-3)" "unprognostic (1.01e-2)" "unprognostic (1.52e-1)" "unprognostic (3.34e-2)" "unprognostic (1.85e-2)" "unprognostic (1.07e-1)" "unprognostic (6.57e-2)" "unprognostic (1.28e-1)" 4.3 5.4 4.3 7.5 4.3 16.9 7.6 5.0 5.6 4.1 3.9 9.5 8.3 6.6 6.3 8.5 5.7 3.2 3.6 4.6 4.2 6.3 6.1 3.7 11.1 4.1 4.0 9.6 4.2 4.0 3.0 7.5 4.0 5.4 10.6 4.2 5.2 3.9 3.2 8.3 9.1 4.9 4.0 6.0 6.7 21.4 4.0 16.4 3.7 2.4 12.1 4.9 5.1 4.7 63.6 15.5 43.8 42.2 6.5 11.2 67.0 32.6 16.8 31.5 27.1 31.0 34.2 69.0 23.6 12.5 37.8 21.1 43.3 24.8 37.6 39.7 48.3 79.3 16.8 40.4 4.3 68.7 25.8 4.9 10.6 26.5 18.9 10.3 22.4 68.9 93.9 56.3 31.1 43.5 79.0 61.9 90.7 43.7 45.0 68.1 65.4 64.4 22.1 21.4 52.4 25.8 49.9 41.7 30.9 31.3 50.8 41.4 13.2 39.2 72.6 30.9 34.1 30.3 51.8 86.8 25.0 108.9 36.4 4.6 7.7 13.0 14.3 10.6 14.4 30.0 15.7 16.6 7.4 29.6 21.4 15.7 2.5 16.9 19.8 20.0 23.5 9.3 4.3 4.3 5.0 5.6 4.6 4.2 4.1 4.0 4.0 4.0 4.0 4.7 8.4 19.2 8.9 1.6 9.5 15.6 7.7 16.9 9.1 9.2 15.0 17.5 5.3 11.5 10.9 11.0 4.2 36.8 11.2 5.6 13.7 13.2 7.5 16.6 12.8 8.4 6.1 22.9 6.8 12.3 53.1 12.4 5.1 15.0 3.8 29.7 12.5 7.4 16.6 8.4 5.2 21.1 14.2 6.3 6.2 7.4 10.5 6.5 5.4 2.8 7.8 10.1 18.6 5.5 6.5 10.8 6.2 10.1 13.9 5.6 3.0 17.2 10.6 7.3 19.7 16.1 12.0 109.9 86.0 20.1 14.8 14.6 7.8 16.5 20.0 5.9 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MMS22L "C6orf167, dJ39B17.2" ENSG00000146263 "MMS22 like, DNA repair protein" Q6ZRQ5 6 97142161-97283217 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Oligodendrocytes: 52.3;Spermatocytes: 56.9;Spermatogonia: 45.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA067042 Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067042: AB_2685768" "unprognostic (3.61e-2)" "unprognostic (2.80e-1)" "unprognostic (2.26e-2)" "unprognostic (1.97e-3)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.00e-5)" "unprognostic (9.63e-2)" "unprognostic (5.81e-3)" "unprognostic (8.21e-3)" "unprognostic (9.39e-2)" "unprognostic (6.58e-2)" "unprognostic (1.34e-6)" "unprognostic (3.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" 1.1 1.1 0.7 2.0 1.8 7.0 2.3 1.3 1.2 1.6 0.7 1.6 1.2 1.5 0.5 1.7 1.4 1.0 0.7 0.7 1.0 0.8 0.9 1.1 3.4 2.1 1.4 1.4 1.3 1.4 0.5 2.0 1.8 1.3 2.3 2.4 1.0 0.8 0.6 2.9 1.6 1.5 1.2 1.4 1.1 6.8 1.5 5.2 1.1 0.5 3.4 1.3 1.1 2.4 7.5 8.2 13.5 14.8 2.2 4.0 10.6 15.0 6.9 13.8 20.1 11.4 8.6 16.4 9.0 5.7 16.0 13.4 17.1 8.3 27.4 14.1 12.7 16.7 11.3 7.2 1.3 25.8 11.3 2.2 4.3 19.5 9.0 2.8 6.0 15.2 23.1 25.6 13.1 8.9 9.5 10.4 5.2 12.1 6.1 15.8 12.8 5.8 5.9 9.7 7.7 6.6 9.8 4.9 4.0 7.6 7.6 15.7 4.5 14.0 13.3 11.8 20.8 3.2 10.3 18.3 8.0 16.0 15.7 0.5 0.4 0.9 0.6 0.7 1.0 0.5 0.9 1.0 1.1 0.7 0.8 1.1 0.4 0.6 1.6 1.2 0.9 0.4 0.7 1.8 1.3 1.2 0.7 1.0 2.1 1.4 1.8 1.2 1.5 2.4 5.9 3.2 8.6 16.6 9.7 9.2 5.8 4.0 4.0 11.6 6.1 6.2 4.2 5.7 6.9 3.7 41.7 12.5 14.6 3.3 1.9 2.9 67.8 4.4 6.1 6.5 1.2 26.3 11.3 4.1 11.2 6.1 7.7 2.8 7.6 24.0 10.8 3.1 6.4 3.3 7.7 8.4 8.2 7.5 6.0 17.2 9.9 6.8 7.2 36.5 6.4 6.1 6.2 22.6 52.3 3.0 2.0 5.7 13.1 2.9 5.4 0.8 6.1 31.9 6.6 7.9 5.1 56.9 45.8 7.1 8.2 3.6 9.6 5.2 10.3 3.0 MND1 GAJ ENSG00000121211 "Meiotic nuclear divisions 1" Q9BWT6 4 153344649-153415118 "Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.3;lymphoid tissue: 26.7;testis: 15.9" "Cell type enhanced" "Detected in many" "Early spermatids: 25.9;Erythroid cells: 30.9;Spermatocytes: 55.5;Spermatogonia: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;T-reg: 1.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043499 Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA043499: AB_2732506" "unprognostic (2.21e-2)" "unprognostic (6.46e-3)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (6.21e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.28e-2)" "unprognostic (1.28e-2)" "unprognostic (9.43e-2)" "unprognostic (2.71e-8)" "unprognostic (7.65e-2)" "unprognostic (5.70e-2)" "unprognostic (9.84e-2)" "unprognostic (7.64e-2)" 0.5 0.5 1.1 4.7 1.2 13.3 2.5 1.0 2.0 0.7 0.7 4.4 3.0 0.7 1.2 3.3 0.5 1.0 0.4 1.1 1.3 0.6 1.3 0.8 12.0 1.4 1.1 0.3 0.3 0.0 0.3 2.4 1.2 0.5 5.1 0.0 0.9 0.9 1.3 2.1 2.6 1.5 1.1 1.8 1.6 15.9 1.3 26.7 0.4 0.5 14.0 1.3 1.3 1.7 38.6 17.7 52.7 30.6 0.7 7.2 20.9 35.1 15.4 31.4 25.6 32.8 26.1 74.4 5.8 8.5 29.5 15.7 52.3 15.8 39.9 47.7 19.9 39.1 17.3 42.9 1.1 88.2 17.9 1.9 3.3 24.4 21.1 7.8 10.7 86.0 71.0 91.9 26.8 21.5 124.1 116.0 39.1 17.9 17.8 74.1 18.2 35.8 19.3 9.7 26.5 23.3 15.7 17.7 30.0 26.5 14.7 72.1 2.6 24.1 34.8 28.1 32.6 79.0 96.0 58.8 24.1 69.6 28.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.0 0.4 0.0 0.1 1.7 0.1 1.1 1.2 1.0 2.0 1.1 1.3 1.4 1.1 1.2 1.1 1.3 1.7 0.2 0.0 0.5 2.6 1.9 2.8 1.8 5.1 0.0 0.0 2.2 4.6 0.6 2.8 0.7 0.0 0.0 14.5 1.0 4.1 1.9 0.3 25.9 3.5 1.6 1.3 0.0 30.9 1.6 0.5 20.6 3.6 2.0 5.7 0.0 11.8 1.4 1.0 12.5 0.0 2.6 4.3 4.1 2.5 5.0 20.5 0.9 2.4 3.6 1.9 0.1 0.0 1.0 2.0 23.3 0.6 1.6 2.2 7.7 1.2 0.7 0.1 1.0 0.0 6.6 0.9 8.6 55.5 96.3 10.2 1.4 2.5 2.5 1.5 10.3 2.7 MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "bone marrow: 4023.1" "Cell type enriched" "Detected in some" 30 "Erythroid cells: 87.4" "Cancer enhanced" "Detected in single" "stomach cancer: 1.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 6.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 94 "HL-60: 3517.4;NB-4: 4589.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" No NA 576000000 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles Nucleoplasm "CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (4.62e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.78e-1)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (6.92e-2)" "unprognostic (8.34e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-3)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" 0.5 0.4 0.8 0.6 0.6 4023.1 0.3 0.6 1.1 0.0 0.3 0.2 0.0 0.2 1.1 0.1 0.1 0.3 1.1 0.8 0.7 0.2 1.8 8.4 1.7 0.9 1.0 0.1 0.1 0.0 1.5 1.4 0.9 0.2 0.2 0.4 66.3 0.1 1.1 4.3 0.2 0.3 0.8 21.7 0.1 0.4 0.8 10.9 0.3 0.3 0.2 0.5 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 3517.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4589.9 0.0 0.0 0.0 5.3 3.2 0.6 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 4.0 0.0 0.0 6.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.1 7.5 0.8 0.6 0.6 1.1 0.8 0.7 0.9 1.0 0.9 0.8 0.8 0.7 0.0 0.0 0.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.9 0.0 0.5 0.1 0.0 0.1 0.0 87.4 0.3 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.7 0.3 0.9 0.0 0.2 0.0 0.0 1.2 0.0 1.3 0.0 2.9 0.0 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.1 0.3 0.1 0.0 0.1 0.6 0.0 0.0 0.0 MRPL37 "MRP-L2, RPML2" ENSG00000116221 "Mitochondrial ribosomal protein L37" Q9BZE1 1 54184041-54225464 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025767, HPA025826, HPA025951" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA025767: AB_1854105, HPA025826: AB_1854106, HPA025951: AB_1854107" "unprognostic (2.00e-1)" "unprognostic (6.81e-2)" "prognostic favorable (6.99e-4)" "unprognostic (1.71e-3)" "unprognostic (8.24e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (2.49e-2)" "unprognostic (1.56e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-2)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic favorable (9.25e-4)" "unprognostic (2.43e-1)" "unprognostic (2.62e-1)" "unprognostic (7.67e-3)" 44.7 73.8 28.6 32.4 30.6 67.4 41.5 35.5 37.2 36.1 42.7 50.7 51.5 34.7 26.9 65.8 38.2 25.5 86.3 31.5 29.8 55.4 108.1 30.2 41.1 32.5 30.3 41.0 67.7 47.2 20.8 31.5 33.2 33.8 53.5 21.8 41.3 29.8 167.9 56.2 41.0 41.6 27.4 34.6 49.2 31.4 30.8 41.2 28.5 154.2 51.3 37.9 40.5 28.7 168.3 94.9 84.6 114.5 83.4 110.9 150.5 111.2 103.5 194.0 167.7 190.7 75.4 226.1 98.2 125.3 184.8 131.6 168.2 164.6 150.6 111.1 211.7 194.8 186.9 194.8 142.9 233.3 87.1 123.2 138.7 201.8 156.5 108.7 176.1 174.2 219.2 66.1 140.2 123.3 161.7 226.4 173.5 134.4 208.2 175.3 171.7 191.6 110.8 123.4 166.3 77.6 153.8 261.4 214.0 110.6 113.2 260.7 88.5 123.6 112.2 157.7 227.1 83.1 126.0 175.5 161.1 234.2 119.9 53.0 103.4 45.4 67.5 91.8 79.1 120.4 81.9 76.1 120.4 105.1 82.0 72.8 5.6 94.0 88.7 101.5 116.4 126.6 28.6 30.6 35.5 37.2 31.5 29.8 32.5 30.3 33.2 27.4 30.8 28.7 24.0 22.4 18.7 3.9 33.4 34.7 43.8 84.6 45.5 8.9 46.3 57.0 71.3 55.8 43.1 18.4 2.1 118.0 15.5 36.6 80.3 81.2 31.0 25.7 23.2 30.3 33.1 103.3 7.5 96.3 145.8 37.3 41.8 33.1 14.5 40.6 37.5 156.5 87.0 6.7 8.4 53.0 52.9 43.6 25.6 57.5 26.1 30.9 23.2 4.7 53.1 9.2 24.7 4.5 5.4 69.0 41.1 28.6 72.2 54.2 73.8 105.2 29.4 8.7 13.1 28.8 34.3 23.6 50.4 79.6 37.4 73.9 24.5 57.2 86.0 55.2 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MTBP ENSG00000172167 "MDM2 binding protein" Q96DY7 8 120445400-120542133 "Predicted intracellular proteins" "Cell cycle, Growth arrest, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Excitatory neurons: 14.7;Oligodendrocytes: 16.1;Spermatocytes: 16.2;Spermatogonia: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA025694, HPA050594" Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA025694: AB_1854169, HPA050594: AB_2681185" "unprognostic (1.92e-2)" "unprognostic (1.07e-1)" "unprognostic (4.47e-1)" "unprognostic (3.53e-4)" "unprognostic (1.20e-1)" "unprognostic (5.40e-3)" "unprognostic (2.77e-6)" "unprognostic (3.99e-3)" "unprognostic (1.50e-2)" "unprognostic (7.86e-3)" "unprognostic (3.38e-3)" "unprognostic (3.29e-1)" "unprognostic (5.20e-10)" "unprognostic (3.41e-3)" "unprognostic (2.51e-1)" "unprognostic (3.02e-2)" "unprognostic (5.86e-2)" 1.3 1.1 1.0 2.5 1.2 4.0 2.6 3.6 1.7 1.6 0.7 1.7 1.5 2.1 2.4 1.4 1.7 1.2 0.6 1.0 0.9 1.0 0.8 1.3 4.3 1.0 1.0 2.4 0.9 1.0 0.8 2.1 1.2 1.5 2.6 4.3 1.1 1.0 0.7 3.0 1.3 2.0 0.9 1.8 1.1 5.0 1.1 4.6 0.8 0.8 4.0 1.0 1.3 1.4 15.3 4.5 14.6 6.0 2.1 3.5 7.1 11.4 6.5 16.4 21.0 4.9 8.3 13.8 11.2 3.8 4.9 13.0 13.9 6.8 20.3 11.5 10.6 11.6 6.7 5.6 1.1 12.4 8.6 1.3 2.9 12.7 8.1 2.5 7.3 12.6 7.6 10.2 9.7 6.9 19.8 7.6 6.5 12.0 9.0 11.3 15.0 9.8 3.9 5.3 7.4 8.6 7.7 44.8 7.0 7.9 8.5 8.9 4.5 7.0 12.7 9.0 18.6 3.9 8.9 8.0 6.6 15.1 8.3 0.0 0.1 0.1 0.3 0.6 0.5 0.7 0.5 0.7 0.2 0.5 0.8 0.7 0.0 0.5 0.3 0.0 0.7 0.3 1.0 1.2 3.6 1.7 1.0 0.9 1.0 1.0 1.2 0.9 1.1 1.4 1.6 0.0 1.5 7.5 2.9 0.8 1.7 1.5 1.8 0.0 1.4 1.3 1.1 0.0 1.1 1.8 0.0 2.3 2.5 0.5 0.0 0.9 0.8 1.3 2.6 1.1 0.0 12.8 14.7 1.8 3.0 2.5 2.6 1.5 2.5 5.0 1.8 0.9 1.6 0.0 9.1 0.9 0.0 0.3 1.8 0.4 1.5 1.7 1.8 3.7 1.0 0.0 2.1 9.0 16.1 0.6 0.1 1.2 2.3 1.2 0.3 0.3 2.4 0.0 0.0 5.6 2.6 16.2 10.2 1.4 0.6 0.7 3.3 1.5 0.8 0.8 MTFR2 "DUFD1, FAM54A" ENSG00000146410 "Mitochondrial fission regulator 2" Q6P444 6 136231024-136250335 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 6.4;testis: 7.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 23.6;Spermatocytes: 27.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA029792, HPA029794" Approved Uncertain Vesicles NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA029792: AB_10600210, HPA029794: AB_10600535" "unprognostic (6.49e-3)" "unprognostic (6.29e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.64e-4)" "unprognostic (3.93e-1)" "unprognostic (1.75e-2)" "unprognostic (4.60e-6)" "prognostic unfavorable (8.28e-4)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.27e-2)" "unprognostic (6.54e-2)" "unprognostic (1.11e-16)" "unprognostic (8.82e-3)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (3.64e-2)" 0.8 0.5 0.4 3.6 0.3 16.3 1.0 0.4 0.6 0.6 0.2 2.9 2.8 0.5 0.3 2.6 0.3 0.3 0.3 0.4 0.3 0.6 0.4 1.2 6.4 0.4 0.5 0.3 0.4 0.0 0.4 1.8 0.3 0.4 3.8 0.5 0.8 0.2 1.2 1.9 2.3 1.1 0.4 2.2 1.2 7.0 0.4 6.2 0.3 0.1 5.3 0.8 0.9 0.4 15.2 11.5 9.7 18.2 1.6 2.8 17.4 19.6 13.6 22.8 31.7 20.7 12.2 39.2 11.7 7.9 30.1 23.1 22.3 14.4 33.8 22.1 17.1 31.0 7.8 18.9 1.0 57.4 28.1 2.3 3.1 25.5 16.1 2.7 12.4 33.8 33.9 29.6 17.2 20.2 32.5 47.8 9.8 20.2 14.1 29.3 15.5 19.7 9.9 11.6 7.7 7.6 12.4 21.5 11.3 11.9 9.1 39.1 6.8 11.3 11.8 40.2 30.4 11.2 28.3 26.1 6.5 38.5 17.6 0.0 0.2 0.0 0.3 0.9 0.1 0.4 0.4 0.7 0.9 0.3 0.0 0.4 0.0 0.0 0.7 0.7 0.7 0.3 0.4 0.3 0.4 0.6 0.4 0.3 0.4 0.5 0.3 0.4 0.4 0.4 2.0 0.0 1.1 0.0 2.2 1.0 0.6 3.1 0.0 0.0 3.4 3.6 0.4 0.0 2.3 0.0 0.0 8.4 1.3 2.2 0.0 1.1 7.9 2.4 1.3 1.7 0.0 9.9 0.5 2.5 23.6 1.5 2.6 2.5 1.3 3.5 0.7 0.5 6.6 0.0 0.4 2.1 4.1 3.8 2.1 5.9 0.3 2.5 0.0 1.0 2.3 0.0 1.0 0.5 0.0 1.3 0.4 0.0 7.4 1.2 1.3 1.4 2.5 0.0 0.0 5.3 1.8 27.6 13.0 5.3 0.3 3.0 3.1 0.8 4.6 0.9 MXD3 "bHLHc13, MAD3" ENSG00000213347 "MAX dimerization protein 3" Q9BW11 5 177301461-177312757 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.7;Granulosa cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.7" "Group enriched" "Detected in many" 5 "B-cells: 4.1;granulocytes: 16.7;monocytes: 10.9" "Cell line enhanced" "Detected in many" "HDLM-2: 176.0" "Group enriched" "Detected in many" 5 "amygdala: 1.8;basal ganglia: 2.0;cerebral cortex: 1.1;hippocampal formation: 1.0;white matter: 2.4" "Low region specificity" "Detected in all" HPA070111 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA070111: AB_2686228" "unprognostic (2.78e-1)" "unprognostic (1.32e-2)" "unprognostic (2.11e-1)" "unprognostic (3.63e-1)" "unprognostic (8.26e-2)" "unprognostic (6.18e-3)" "prognostic unfavorable (3.60e-4)" "unprognostic (3.32e-1)" "unprognostic (6.84e-2)" "unprognostic (3.12e-2)" "unprognostic (4.97e-2)" "unprognostic (2.84e-2)" "unprognostic (3.33e-16)" "unprognostic (8.55e-3)" "unprognostic (2.22e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-3)" 5.8 5.1 1.9 6.5 2.1 39.3 6.1 1.6 4.6 7.1 2.0 9.4 7.1 5.6 1.4 13.2 7.9 1.0 4.8 1.7 2.0 6.3 14.2 8.3 7.8 2.7 2.0 5.5 12.1 0.4 8.5 1.9 2.6 9.9 0.8 0.4 6.7 1.8 4.0 10.8 10.8 1.2 1.6 19.0 8.1 6.8 2.7 10.5 7.1 0.4 2.4 6.8 7.8 4.0 24.2 16.8 9.9 27.3 0.6 1.3 16.8 31.2 10.0 13.6 13.0 11.9 24.6 12.9 12.6 4.2 7.8 12.1 1.1 3.6 0.7 176.0 22.1 7.7 25.5 16.3 1.4 7.5 21.3 1.1 1.8 0.9 0.6 1.2 12.7 55.1 4.6 39.0 2.8 31.2 64.9 19.7 3.7 7.8 28.2 31.5 30.9 18.7 3.1 3.7 24.3 20.3 19.9 19.9 11.1 1.6 31.3 18.4 9.5 16.5 41.6 13.1 17.0 51.1 18.6 14.8 12.9 24.3 9.7 4.1 3.1 9.9 0.7 9.1 0.0 1.8 0.2 0.1 2.1 4.1 0.1 0.4 16.7 1.0 10.9 1.3 0.9 1.7 1.9 2.1 1.6 4.6 1.7 2.0 2.7 2.0 2.6 1.6 2.7 4.0 1.9 3.2 3.6 5.2 4.9 5.6 2.5 4.9 0.6 2.6 7.0 5.1 2.2 2.8 4.6 5.5 0.0 16.7 4.8 8.9 0.0 1.3 15.5 3.8 3.7 4.1 1.8 45.7 3.4 3.9 6.6 6.0 8.6 3.4 9.5 24.5 4.6 4.3 10.3 3.3 3.0 10.9 4.1 6.0 5.0 2.2 1.8 6.5 3.6 1.9 5.2 1.7 2.1 2.0 3.6 2.3 3.4 1.5 18.5 3.9 4.4 0.8 6.6 2.3 0.0 2.1 4.4 1.0 6.2 10.2 5.7 13.1 5.6 1.9 12.5 3.4 MZT1 "C13orf37, FLJ21869, LOC440145, MGC150539, MOZART1, RP11-11C5.2" ENSG00000204899 "Mitotic spindle organizing protein 1" Q08AG7 13 72708367-72727629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063299, HPA066715" Approved NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA063299: AB_2684980, HPA066715: AB_2685709" "unprognostic (1.52e-1)" "unprognostic (3.38e-2)" "unprognostic (1.48e-1)" "unprognostic (4.89e-1)" "unprognostic (2.46e-1)" "unprognostic (2.38e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (2.65e-2)" "unprognostic (6.88e-2)" "unprognostic (5.28e-2)" "unprognostic (7.09e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.01e-5)" "unprognostic (9.01e-3)" "unprognostic (5.23e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" 9.0 15.1 11.8 11.6 15.5 26.3 11.6 12.6 18.4 8.6 10.2 8.8 8.3 8.3 9.1 9.8 6.1 6.1 12.0 12.3 12.7 11.1 5.5 8.1 17.2 10.4 11.3 7.3 5.8 8.2 6.7 10.6 10.1 10.3 10.0 9.9 9.5 6.3 19.2 9.6 7.4 7.2 11.3 9.8 9.2 6.4 13.1 17.5 12.1 15.0 13.1 9.3 6.1 10.8 97.5 15.4 53.1 39.4 10.8 18.0 43.5 77.1 31.9 47.7 54.8 28.9 62.3 66.9 57.5 30.9 30.1 30.8 53.6 28.7 86.1 80.6 54.5 86.9 30.0 44.0 15.0 147.1 68.1 9.8 28.8 28.9 59.4 28.8 49.1 76.7 48.7 51.1 95.1 17.5 75.2 81.9 40.5 58.7 28.7 52.6 60.7 33.2 42.9 23.8 62.3 56.9 32.7 47.8 48.4 29.0 36.1 72.1 33.5 41.9 47.7 59.5 94.8 46.5 77.0 53.1 98.2 88.8 87.6 16.2 3.8 8.5 4.8 6.9 6.0 7.7 6.5 6.0 4.8 7.3 8.3 6.7 2.0 7.2 7.6 6.3 9.9 3.8 11.8 15.5 12.6 18.4 12.3 12.7 10.4 11.3 10.1 11.3 13.1 10.8 29.3 0.0 15.2 5.5 49.9 55.1 27.6 32.2 30.7 29.3 32.8 24.5 17.8 12.8 18.7 31.3 14.6 57.3 38.3 10.3 58.7 25.9 4.5 20.5 18.0 26.5 21.7 122.3 15.2 24.4 98.8 23.1 18.3 18.8 18.4 27.0 20.7 8.8 41.3 63.9 17.1 17.6 38.7 32.3 46.4 4.2 19.9 33.1 60.5 3.7 36.0 31.1 23.7 6.0 10.0 25.1 15.2 16.6 47.9 33.7 8.1 46.5 12.9 27.7 32.9 21.4 26.8 52.0 38.2 51.9 57.4 30.2 43.8 17.6 24.2 32.3 NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes 34000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "CAB012423: , HPA036947: AB_10671367, HPA037363: AB_10672483" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.79e-8)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (5.00e-2)" "unprognostic (5.41e-3)" "unprognostic (4.53e-1)" "prognostic unfavorable (1.13e-7)" "unprognostic (4.80e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-1)" "unprognostic (8.75e-2)" 8.3 7.4 7.3 21.5 11.4 35.5 10.9 9.9 8.3 10.2 7.4 17.9 17.0 10.7 10.6 15.9 11.2 9.8 7.6 7.2 8.0 7.4 4.8 10.6 38.1 11.0 10.0 8.0 7.7 11.3 5.5 17.5 11.7 9.4 20.4 11.1 11.8 10.2 7.9 21.9 16.0 13.4 8.4 16.1 12.1 18.2 10.2 76.8 11.3 10.2 44.8 10.1 9.3 13.9 125.3 99.3 134.6 97.9 29.9 28.4 159.2 76.1 69.8 138.3 109.1 123.5 150.8 135.8 24.2 63.2 126.7 128.6 188.0 105.4 194.1 214.1 92.8 112.2 113.8 79.4 12.5 145.0 96.5 20.5 31.6 112.4 107.8 61.9 89.9 94.0 71.0 63.4 104.7 79.6 162.2 73.8 207.5 129.9 78.2 153.7 260.6 77.7 39.5 64.1 54.0 61.9 121.5 64.9 44.3 189.1 27.0 101.7 51.0 94.1 149.6 60.8 168.4 45.3 51.7 181.0 55.7 92.2 126.1 11.0 1.7 3.7 7.1 2.8 5.3 5.1 6.4 7.3 3.4 3.5 7.3 7.3 1.4 8.1 2.2 4.1 8.3 3.9 7.3 11.4 9.9 8.3 7.2 8.0 11.0 10.0 11.7 8.4 10.2 13.9 4.3 6.4 7.4 4.9 11.0 3.6 3.8 4.4 17.1 3.7 4.7 6.9 4.1 5.7 3.4 1.8 8.4 13.5 8.9 7.3 0.0 4.5 18.3 5.3 6.3 5.4 1.2 48.0 5.6 3.7 17.8 6.4 7.1 5.8 3.8 20.0 8.9 3.3 10.1 5.0 5.0 9.9 6.1 16.4 4.4 34.3 5.9 10.8 0.0 2.8 9.5 11.8 15.5 2.5 17.8 5.3 4.6 6.0 22.6 4.1 6.0 2.4 4.2 8.4 0.0 4.2 5.2 21.3 13.7 19.3 3.4 6.3 12.0 6.1 14.7 4.1 NCAPD3 "CAP-D3, FLJ42888, hCAP-D3, hcp-6, hHCP-6, KIAA0056" ENSG00000151503 "Non-SMC condensin II complex subunit D3" P42695 11 134150113-134225454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 58.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 8 "prostate cancer: 50.8" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040286 Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA040286: AB_2676918" "unprognostic (4.27e-2)" "unprognostic (6.05e-2)" "unprognostic (7.78e-3)" "unprognostic (8.22e-3)" "unprognostic (2.79e-1)" "unprognostic (4.29e-2)" "unprognostic (2.15e-3)" "unprognostic (2.56e-1)" "unprognostic (4.32e-2)" "unprognostic (4.75e-1)" "unprognostic (2.79e-3)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.93e-2)" "unprognostic (3.35e-2)" "unprognostic (3.94e-1)" "unprognostic (3.48e-1)" 4.7 5.5 1.9 3.1 2.0 10.0 4.9 4.0 3.8 4.2 2.3 4.4 3.5 4.0 3.3 7.1 3.8 2.6 5.0 3.1 1.6 3.6 8.8 4.9 4.2 2.0 1.1 3.4 4.5 1.9 7.0 3.1 1.1 58.5 1.5 4.5 5.7 0.9 3.7 9.0 5.4 1.3 0.9 6.2 5.1 9.5 1.6 3.1 6.0 0.9 1.7 3.7 5.2 3.0 5.5 1.9 12.3 25.3 1.8 1.3 10.6 11.5 1.9 3.5 4.0 5.6 3.4 6.1 11.1 3.5 9.8 6.1 3.5 5.2 4.4 9.2 21.7 26.6 5.1 8.5 2.3 13.1 15.4 1.7 1.1 5.1 2.0 3.6 2.6 11.6 7.1 4.7 4.2 6.0 10.9 15.1 8.6 5.5 13.8 2.9 13.7 8.5 4.1 3.2 22.1 13.4 9.1 5.9 1.7 10.0 9.7 6.9 1.7 11.8 5.7 11.8 9.9 4.5 4.5 5.5 8.3 16.4 15.2 1.6 3.3 1.6 5.7 2.7 2.2 2.3 3.7 3.8 2.5 5.2 5.5 5.8 1.6 1.7 2.2 8.0 6.5 1.9 1.9 2.0 4.0 3.8 3.1 1.6 2.0 1.1 1.1 0.9 1.6 3.0 7.7 3.2 8.1 8.5 12.1 9.2 4.4 6.0 8.0 20.2 9.9 8.6 6.7 2.8 7.0 12.9 10.4 13.0 13.2 5.4 0.0 2.7 7.2 7.8 12.8 5.6 7.8 32.8 19.7 2.6 9.9 7.5 7.7 9.0 2.5 19.6 5.7 9.7 8.8 11.8 16.7 7.2 10.2 6.4 8.7 10.4 4.7 10.9 1.8 15.0 17.1 9.0 17.5 11.1 16.0 2.8 1.6 4.1 22.9 8.8 3.2 3.6 4.9 20.9 0.0 9.5 9.2 21.5 14.4 10.7 9.1 4.5 14.2 11.3 11.6 3.4 NCAPG "CAP-G, FLJ12450, hCAP-G, YCG1" ENSG00000109805 "Non-SMC condensin I complex subunit G" Q9BPX3 4 17810979-17844865 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Extravillous trophoblasts: 26.6;Plasma cells: 20.4;Spermatocytes: 63.7;Spermatogonia: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.6" "Low region specificity" "Detected in all" HPA039613 Uncertain NA Yes 9500 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA039613: AB_10805481" "unprognostic (5.23e-2)" "unprognostic (3.37e-1)" "unprognostic (1.59e-3)" "prognostic unfavorable (8.28e-4)" "unprognostic (4.22e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (1.18e-3)" "unprognostic (1.63e-2)" "unprognostic (6.70e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.44e-2)" "unprognostic (0.00e+0)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" 0.7 0.5 0.1 4.1 0.1 13.9 0.9 0.5 0.1 0.7 0.2 3.0 3.8 0.6 0.0 3.5 0.2 0.9 0.3 0.0 0.2 0.2 0.7 0.6 8.7 0.6 1.2 0.2 0.2 0.1 0.1 3.0 0.7 0.3 2.4 0.3 0.7 0.0 0.2 3.5 3.2 1.0 1.2 2.1 1.9 5.6 0.3 15.8 0.3 0.1 8.7 1.2 1.0 0.2 45.1 28.3 63.8 42.2 4.0 7.8 23.1 56.8 22.2 55.0 55.8 36.3 26.8 66.8 11.3 16.0 47.6 19.9 54.5 22.1 74.8 30.5 27.0 53.6 37.3 29.8 0.2 38.4 20.3 1.5 1.5 40.7 18.6 8.8 27.9 28.9 53.1 74.1 55.0 13.4 44.1 36.9 32.8 26.1 27.9 42.8 57.4 28.0 16.6 13.9 50.0 29.7 51.2 10.9 15.7 27.2 25.6 21.3 23.2 52.5 23.6 30.0 78.9 23.2 23.3 56.1 21.7 39.1 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.4 0.1 0.1 0.5 0.1 0.0 0.2 0.6 1.2 0.7 1.2 0.3 0.2 0.3 0.0 1.1 0.0 3.3 2.4 0.6 1.9 1.2 0.2 0.6 0.6 0.2 0.0 0.8 0.0 0.0 11.7 1.6 2.9 0.0 0.1 15.8 0.9 1.9 1.7 1.8 59.3 0.2 0.0 26.6 3.8 7.1 2.3 1.3 14.2 2.2 0.5 9.5 0.0 0.4 3.1 2.0 2.6 2.9 9.5 0.6 3.7 1.8 1.0 0.7 0.3 3.1 0.5 0.5 0.2 0.1 0.0 20.4 0.4 0.2 0.0 0.0 0.2 0.0 0.2 4.3 63.7 24.3 11.0 1.1 2.2 3.7 0.7 5.6 1.3 NCAPG2 "CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB" ENSG00000146918 "Non-SMC condensin II complex subunit G2" Q86XI2 7 158631169-158704804 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 24.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026631, HPA049637" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear speckles" "HPA026631: AB_1845983, HPA049637: " "unprognostic (2.73e-2)" "unprognostic (1.77e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (1.66e-1)" "prognostic favorable (1.91e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (5.33e-3)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.79e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.19e-2)" "prognostic unfavorable (4.06e-5)" "unprognostic (2.58e-3)" "unprognostic (1.28e-1)" "unprognostic (8.21e-2)" "unprognostic (7.37e-2)" 3.7 2.5 2.0 8.8 2.2 24.4 5.4 2.5 2.1 4.0 1.3 6.9 4.4 4.3 2.1 6.9 3.0 2.9 2.9 2.2 2.1 2.6 4.1 3.1 12.4 2.0 1.7 3.1 2.2 4.6 3.5 5.9 2.1 2.8 7.6 2.8 3.5 2.8 3.4 6.8 5.8 4.8 1.6 4.6 5.6 14.8 1.8 27.9 3.2 4.1 13.8 4.0 3.9 2.4 103.9 53.7 64.1 41.8 9.5 15.4 25.3 74.3 47.4 89.0 99.0 48.5 52.0 64.0 45.0 30.3 95.1 51.7 53.7 33.8 117.2 68.4 40.4 57.2 64.8 38.8 4.2 72.2 62.3 6.8 3.7 73.1 21.0 16.2 50.4 72.9 71.9 91.6 82.8 111.4 119.2 48.8 63.7 58.8 43.3 69.7 67.8 60.6 22.6 45.9 69.6 54.5 91.6 35.0 20.2 40.4 31.4 46.5 25.9 60.6 45.9 166.2 120.6 61.3 48.2 77.2 64.6 89.6 118.5 5.9 0.9 1.1 5.2 1.2 7.5 1.6 5.2 3.6 2.3 1.0 1.6 1.8 0.7 5.2 5.1 1.1 7.2 2.2 2.0 2.2 2.5 2.1 2.2 2.1 2.0 1.7 2.1 1.6 1.8 2.4 3.6 6.4 1.5 3.9 4.1 4.0 2.1 2.8 1.8 3.9 3.7 3.3 4.8 2.8 4.6 1.8 0.0 6.7 5.1 3.4 0.0 2.3 15.1 4.0 4.6 4.3 0.0 19.6 10.7 3.3 10.4 4.5 4.1 5.9 1.3 12.6 2.9 2.6 7.3 8.4 7.2 2.9 2.0 3.8 5.2 7.2 2.8 4.4 1.8 3.7 2.7 2.1 2.1 10.1 10.7 2.3 0.4 4.1 11.0 1.1 0.3 1.3 6.0 2.8 6.6 4.3 5.7 48.2 18.5 6.1 2.0 2.6 4.9 5.0 5.7 3.0 NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.2;lymphoid tissue: 37.4;testis: 35.4" "Cell type enhanced" "Detected in many" "Plasma cells: 26.3;Spermatocytes: 89.3;Spermatogonia: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoplasm "HPA002647: AB_1078300, HPA003008: AB_1078301" "unprognostic (5.52e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "prognostic unfavorable (9.53e-6)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (0.00e+0)" "unprognostic (3.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" 1.2 0.7 0.3 9.9 0.4 35.2 1.8 0.9 0.9 1.3 0.1 7.7 5.6 0.9 0.2 6.3 0.5 1.6 0.4 0.3 0.2 0.4 1.0 1.1 20.3 0.1 0.0 0.3 0.3 0.5 0.2 5.2 0.3 0.4 9.3 1.8 1.5 0.2 0.3 4.7 6.2 2.8 0.0 3.7 3.6 35.4 0.1 37.4 0.4 0.1 22.0 2.6 2.0 0.3 134.1 52.0 115.1 60.6 3.9 6.1 80.8 58.7 40.3 115.1 118.4 93.5 71.5 121.0 41.8 26.6 106.2 57.2 100.2 39.6 117.2 110.0 63.4 123.7 49.3 74.5 0.7 112.2 101.3 1.8 4.2 89.1 35.9 10.2 46.6 89.7 89.5 88.8 53.0 59.5 183.8 104.2 85.9 57.6 56.6 133.4 106.7 95.5 23.6 49.6 71.2 52.3 34.8 46.5 19.9 42.4 36.6 80.0 24.1 83.5 126.3 76.9 101.9 44.4 70.1 134.0 33.7 111.5 95.3 3.8 0.0 0.2 0.8 0.9 0.1 0.9 1.2 1.0 0.4 0.9 0.0 0.4 0.3 0.1 0.0 0.0 6.2 0.5 0.3 0.4 0.9 0.9 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 4.9 0.0 0.0 0.0 3.5 0.6 0.7 1.9 1.2 0.4 1.0 0.8 0.5 0.0 1.6 0.0 8.4 9.4 2.0 2.1 0.0 0.5 5.9 1.7 0.9 1.8 0.0 16.4 0.4 0.0 16.3 1.8 4.1 1.2 1.3 5.5 1.4 0.4 8.5 0.0 0.3 2.8 0.0 3.8 3.7 4.9 0.9 2.2 1.8 0.0 0.2 8.5 0.0 0.5 1.0 0.2 0.1 0.4 26.3 0.7 0.4 0.0 1.6 2.3 0.0 0.2 3.5 89.3 29.4 8.8 0.9 1.9 5.1 0.6 5.7 1.1 NCAPH2 "384D8-2, CAP-H2, hCAP-H2" ENSG00000025770 "Non-SMC condensin II complex subunit H2" Q6IBW4 22 50508224-50524780 "Predicted intracellular proteins" "DNA condensation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067932, HPA069056" Enhanced Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge" "HPA067932: AB_2685926, HPA069056: AB_2686076" "unprognostic (2.01e-1)" "prognostic favorable (2.24e-8)" "unprognostic (3.65e-2)" "unprognostic (2.81e-1)" "unprognostic (5.04e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (2.92e-2)" "unprognostic (8.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.26e-2)" "unprognostic (6.31e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" 25.7 21.9 32.9 24.5 33.6 78.8 26.9 32.7 39.2 31.8 25.4 29.3 17.7 29.8 12.4 30.3 30.0 13.0 36.7 32.0 30.9 26.6 27.6 28.2 27.6 32.6 29.0 37.6 40.7 16.7 38.6 17.1 28.7 28.4 11.7 15.5 25.7 16.6 30.7 32.6 28.4 14.7 27.5 33.2 30.2 52.3 28.5 29.6 28.9 19.3 20.2 25.9 26.9 33.5 60.7 32.1 53.8 57.1 15.8 18.4 71.6 45.8 31.6 81.8 89.5 67.2 41.4 68.8 25.5 32.9 45.5 47.1 49.0 44.2 23.5 40.3 82.8 39.8 86.7 63.6 19.1 90.3 69.5 16.1 27.6 64.4 22.2 12.2 26.2 59.4 51.5 132.5 33.4 83.9 61.7 109.9 39.3 34.9 37.9 103.3 71.0 77.2 23.8 40.6 35.6 47.5 36.7 55.4 44.3 16.5 37.5 86.7 17.6 64.2 80.5 54.4 72.3 67.7 45.8 110.1 48.8 45.7 62.3 11.9 9.8 18.2 18.7 11.6 22.9 16.0 19.4 19.1 8.0 14.2 19.9 17.3 11.4 13.9 14.4 11.8 19.3 15.5 32.9 33.6 32.7 39.2 32.0 30.9 32.6 29.0 28.7 27.5 28.5 33.5 10.1 22.4 24.5 12.1 15.9 18.9 23.8 17.5 6.2 18.3 11.5 12.6 19.6 15.7 10.4 9.2 4.2 36.3 15.5 24.6 15.6 16.6 36.8 8.5 7.5 12.9 13.1 31.5 8.6 23.5 55.1 13.8 14.8 14.5 17.1 16.3 8.9 10.6 19.3 8.4 8.8 18.8 6.1 7.9 16.3 111.5 17.4 9.2 12.4 3.7 16.2 14.7 18.6 3.0 8.2 17.3 13.5 17.3 26.6 15.2 18.4 9.5 5.9 16.1 19.7 17.8 16.9 36.2 39.7 10.9 18.5 31.5 15.9 7.6 22.6 18.2 NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: AB_2686189, HPA070882: AB_2686320" "unprognostic (2.51e-1)" "unprognostic (1.93e-1)" "prognostic favorable (4.48e-5)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "prognostic unfavorable (7.52e-7)" "unprognostic (3.46e-3)" "unprognostic (1.53e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.58e-4)" "unprognostic (9.27e-2)" "unprognostic (6.22e-3)" "unprognostic (3.00e-3)" "unprognostic (4.38e-2)" "unprognostic (9.24e-2)" "unprognostic (6.07e-2)" 5.4 5.2 3.4 9.5 3.5 8.4 11.1 3.6 4.1 5.7 3.6 11.9 8.9 6.5 7.4 7.7 7.5 4.6 4.5 3.6 3.4 6.9 7.8 4.7 15.7 3.2 3.3 5.9 4.7 9.5 1.7 8.0 3.3 4.8 14.2 6.0 4.2 5.2 4.3 7.3 8.2 7.1 3.5 5.6 6.4 7.5 3.5 14.2 6.8 5.2 18.4 7.1 4.2 3.9 61.6 31.2 42.8 43.7 15.5 15.5 49.3 40.9 31.0 63.8 51.1 47.5 40.4 119.0 26.2 18.6 51.2 72.0 73.2 43.3 89.8 29.8 50.9 58.5 42.9 40.5 14.3 95.3 31.9 9.4 17.0 62.9 37.5 18.6 39.1 44.2 67.7 16.9 35.6 22.2 47.2 38.2 101.0 52.2 49.9 52.0 68.4 66.0 29.8 41.7 25.4 32.2 36.5 71.5 35.9 45.3 55.3 50.2 22.7 32.9 32.6 45.5 74.9 17.9 48.8 84.7 27.3 71.6 42.2 0.0 2.3 1.5 3.0 5.0 4.7 3.6 2.8 2.7 2.6 2.8 5.3 4.1 0.1 3.1 3.3 2.3 3.4 2.4 3.4 3.5 3.6 4.1 3.6 3.4 3.2 3.3 3.3 3.5 3.5 3.9 4.4 6.4 6.3 12.4 8.7 10.1 6.4 9.0 12.0 4.5 10.1 6.3 8.1 4.3 5.4 5.5 2.1 11.5 5.9 7.9 0.0 8.5 2.3 5.0 5.6 6.1 0.0 19.4 13.8 9.1 20.2 6.3 8.6 4.6 7.6 21.5 5.3 7.1 11.8 3.3 11.0 10.3 16.2 8.2 8.9 2.1 2.8 7.1 7.2 13.1 4.7 3.3 3.1 11.6 19.4 7.0 5.8 3.4 20.1 8.9 2.9 4.5 5.5 2.9 6.6 6.3 15.7 11.8 14.3 18.2 8.5 6.8 6.7 4.3 18.2 6.5 NDC80 "HEC, HEC1, hsNDC80, KNTC2, TID3" ENSG00000080986 "NDC80 kinetochore complex component" O14777 18 2571557-2616635 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.2;lymphoid tissue: 29.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 63.4;Spermatocytes: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 7.2;granulocytes: 8.3;T-cells: 11.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA066330 Supported Nucleoplasm,Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Centrosome "HPA066330: AB_2685661" "unprognostic (1.96e-1)" "unprognostic (5.38e-2)" "unprognostic (2.96e-1)" "unprognostic (2.21e-3)" "unprognostic (1.87e-1)" "unprognostic (3.63e-2)" "prognostic unfavorable (2.53e-8)" "unprognostic (1.16e-2)" "unprognostic (2.58e-3)" "unprognostic (2.86e-2)" "unprognostic (3.19e-3)" "unprognostic (7.74e-2)" "unprognostic (0.00e+0)" "unprognostic (9.69e-3)" "unprognostic (1.69e-1)" "unprognostic (3.50e-2)" "unprognostic (1.71e-1)" 1.8 0.9 1.4 9.6 1.3 31.2 2.5 2.2 1.7 2.7 0.1 7.0 5.9 4.3 2.1 5.6 1.2 2.5 1.2 1.0 0.6 1.2 1.6 1.5 20.5 1.9 0.6 0.8 0.9 0.5 0.1 10.4 2.9 5.3 9.8 0.7 1.1 14.0 0.9 7.9 6.2 5.0 0.4 5.5 3.8 15.1 1.2 29.2 1.6 0.6 19.3 3.2 4.6 2.5 80.3 17.7 86.5 38.6 4.5 9.8 44.5 91.7 49.1 117.7 99.7 49.2 44.0 86.6 40.4 35.9 49.7 47.9 98.2 39.9 123.6 32.2 24.6 68.8 49.5 38.1 1.5 133.2 55.1 5.1 3.7 67.8 47.8 12.0 54.3 52.8 56.8 107.1 104.0 36.2 65.1 57.2 44.9 51.6 25.3 71.0 88.6 69.7 31.0 38.0 69.3 31.4 84.4 21.7 32.7 34.0 36.7 52.4 33.2 75.7 168.1 60.7 123.2 46.5 78.6 116.0 33.5 60.8 65.8 3.5 0.6 2.5 1.8 0.4 1.7 7.2 3.2 3.8 0.2 5.3 2.0 2.0 8.3 1.7 0.5 1.3 11.3 1.3 1.4 1.3 2.2 1.7 1.0 0.6 1.9 0.6 2.9 0.4 1.2 2.5 2.8 0.0 0.6 0.3 5.8 2.3 0.7 3.8 0.6 0.0 0.6 0.9 15.8 0.0 2.4 0.0 0.0 15.5 4.8 2.1 0.0 0.9 22.0 1.3 3.7 1.9 0.0 63.4 0.6 0.4 21.7 6.8 2.6 2.1 0.0 20.8 5.7 0.5 11.5 0.0 0.5 2.8 8.2 3.2 2.4 7.6 7.5 1.7 0.0 1.0 0.4 0.0 7.2 0.5 0.5 0.3 0.1 23.3 14.1 0.4 0.4 0.2 1.4 0.0 19.7 0.6 6.8 82.8 21.1 4.2 0.6 2.1 8.7 9.8 6.2 1.5 NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309874-177362936 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.6;lymphoid tissue: 23.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 14.7;Granulosa cells: 4.8;Plasma cells: 6.1;Squamous epithelial cells: 4.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 72.1;HL-60: 79.1;Karpas-707: 99.1;MOLT-4: 80.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" HPA065761 Enhanced Nucleoplasm NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA065761: AB_2685555" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" 0.1 0.0 0.0 1.7 0.0 6.6 0.3 0.0 0.1 0.2 0.0 1.1 1.1 0.1 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 2.3 1.3 0.5 0.0 0.4 0.6 1.5 0.1 23.6 0.0 0.0 3.5 0.4 0.4 0.0 19.3 15.8 16.4 8.2 1.8 3.3 8.0 23.4 8.6 25.3 14.9 5.8 16.5 21.2 3.4 6.2 25.1 8.8 17.4 9.3 36.6 72.1 11.4 14.7 11.9 15.2 0.5 79.1 9.7 0.3 0.5 26.2 5.6 5.2 9.9 53.9 15.3 99.1 16.7 8.4 80.7 30.2 7.5 5.7 11.5 16.2 11.2 6.8 6.8 2.6 12.8 8.9 11.7 13.4 6.3 7.2 10.9 20.4 4.7 15.2 11.8 7.8 24.0 6.8 4.8 33.5 10.1 27.8 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.1 0.4 1.2 0.0 0.2 0.1 0.4 0.0 1.3 0.0 0.0 2.6 1.6 0.5 0.0 0.0 0.1 0.1 0.6 0.3 0.0 14.7 0.1 0.2 3.3 0.9 0.0 0.5 0.0 4.8 0.4 0.0 1.5 0.0 0.1 1.0 0.0 1.3 0.4 0.2 0.0 1.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 6.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.5 2.7 2.4 4.5 1.3 0.3 1.0 0.5 1.2 0.2 NEMP1 "KIAA0286, TMEM194, TMEM194A" ENSG00000166881 "Nuclear envelope integral membrane protein 1" O14524 12 57055643-57088063 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014394 Uncertain Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA014394: AB_2204899" "unprognostic (9.24e-2)" "unprognostic (1.78e-1)" "unprognostic (1.18e-1)" "unprognostic (4.97e-2)" "unprognostic (1.43e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.93e-4)" "unprognostic (8.36e-2)" "unprognostic (2.42e-3)" "unprognostic (2.11e-1)" "unprognostic (1.64e-1)" "unprognostic (6.61e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.63e-2)" "unprognostic (7.05e-2)" 6.2 5.1 3.3 8.0 3.5 6.8 6.3 3.6 3.9 6.6 3.7 8.7 3.8 8.2 5.3 5.6 6.3 4.3 3.0 3.2 3.3 4.3 6.1 6.3 12.2 3.3 3.2 7.2 4.0 3.7 3.5 7.8 3.7 6.8 6.8 9.3 4.5 5.2 2.3 10.8 7.5 7.4 3.3 7.3 5.4 7.7 3.2 16.1 5.4 3.0 11.6 6.5 5.7 4.2 20.0 16.8 37.5 40.5 12.3 12.0 21.5 30.2 17.1 41.1 33.3 20.0 37.2 47.2 38.1 10.4 35.0 28.8 50.4 13.0 47.0 25.3 22.9 27.9 19.5 10.6 5.2 35.0 30.7 4.1 12.3 33.8 21.0 17.1 11.6 42.2 57.5 91.2 35.0 10.9 38.5 29.7 21.0 18.8 18.4 38.5 53.2 21.5 9.0 12.2 22.3 15.1 25.7 21.3 24.1 26.4 38.5 34.7 8.3 39.0 22.5 36.4 28.6 40.8 83.2 40.5 23.1 32.9 41.1 2.4 0.5 0.8 1.1 1.5 1.5 1.9 1.2 1.5 0.5 1.6 1.8 1.6 0.2 2.4 0.9 0.9 1.2 0.8 3.3 3.5 3.6 3.9 3.2 3.3 3.3 3.2 3.7 3.3 3.2 4.2 4.7 22.4 2.6 0.0 7.1 0.0 3.1 0.0 8.0 2.6 5.0 2.9 1.6 2.8 1.8 5.5 4.2 5.0 4.1 1.4 0.0 1.8 1.2 3.3 4.4 4.0 0.0 12.2 0.0 0.8 3.6 4.4 3.1 3.7 0.0 11.1 5.7 3.6 5.8 1.7 0.0 1.8 0.0 7.1 0.0 1.0 6.2 7.2 0.0 0.0 4.4 3.5 3.1 0.0 0.0 2.0 0.7 5.3 4.9 4.1 1.0 1.3 2.9 4.0 13.1 3.6 3.4 12.2 7.4 7.6 0.0 3.0 4.1 3.1 2.2 2.4 NRM NRM29 ENSG00000137404 Nurim Q8IXM6 6 30688047-30691420 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 60.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA072545, HPA073982" Enhanced "Nuclear membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "HPA072545: AB_2686532, HPA073982: AB_2686649" "unprognostic (2.09e-1)" "unprognostic (6.35e-2)" "unprognostic (1.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.71e-1)" "unprognostic (2.32e-2)" "unprognostic (3.13e-3)" "unprognostic (1.30e-1)" "unprognostic (8.44e-2)" "unprognostic (1.32e-2)" "unprognostic (2.87e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (3.52e-8)" "unprognostic (3.95e-2)" "unprognostic (1.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" 7.6 4.7 0.4 0.6 0.4 1.7 6.1 0.4 0.4 13.0 0.3 6.7 0.2 13.5 0.3 8.8 8.2 0.3 5.3 0.4 0.4 4.4 2.9 7.8 1.0 0.5 0.4 8.1 5.2 0.3 1.7 0.9 0.4 4.8 0.5 0.3 4.2 0.9 2.1 8.1 6.5 1.1 0.4 7.3 3.9 10.9 0.5 1.5 4.8 0.5 1.1 6.9 9.1 0.4 3.0 2.8 5.2 3.7 0.8 2.8 0.6 1.5 2.9 4.7 4.2 3.1 2.1 5.1 1.0 3.1 2.1 4.6 2.9 5.0 1.3 7.1 1.5 3.1 4.0 4.0 1.0 2.4 4.6 1.7 1.8 4.6 1.7 1.6 3.7 4.1 2.8 4.5 3.2 2.7 3.9 2.6 1.1 3.3 1.7 9.2 3.5 6.2 2.1 1.5 1.9 1.7 1.7 2.1 1.0 1.6 3.4 2.4 1.5 4.3 2.3 2.4 2.8 1.6 3.3 1.8 0.6 6.5 5.6 0.3 1.6 0.1 0.4 0.5 0.3 1.8 0.4 0.6 1.4 1.7 0.2 0.2 0.6 0.4 0.2 1.6 0.3 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.5 0.4 0.4 0.4 0.5 0.4 12.1 3.2 2.0 0.7 12.9 9.8 6.3 9.6 5.7 1.7 3.0 7.5 1.9 12.8 4.9 1.8 2.1 23.0 5.1 1.6 3.9 12.2 13.5 1.0 8.4 12.3 1.2 9.2 0.3 5.6 28.1 9.0 1.5 2.7 12.7 5.0 4.6 1.0 17.6 3.3 0.4 3.4 2.0 20.5 18.9 60.1 5.6 12.8 3.6 1.0 25.6 1.2 7.2 0.5 0.3 4.8 0.5 6.0 5.5 1.7 0.5 1.0 0.4 1.9 6.6 7.3 11.6 4.4 2.1 14.6 6.3 5.1 9.9 3.9 6.3 4.3 NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242226-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.6" "Cell type enhanced" "Detected in many" "Late spermatids: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012636 Approved Supported Cytosol No No 21000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA012636: AB_1854696" "unprognostic (1.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (3.01e-3)" "unprognostic (3.37e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.15e-2)" "unprognostic (4.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.29e-1)" "unprognostic (6.71e-2)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" 19.1 8.0 13.7 23.8 16.6 77.6 15.0 14.6 18.0 16.9 10.9 19.1 16.2 12.4 5.4 29.1 12.0 10.5 18.7 15.4 13.6 8.9 6.3 12.4 37.1 16.1 14.1 9.3 9.1 3.2 4.4 10.5 15.6 11.3 11.0 4.3 12.4 7.0 21.3 33.8 16.8 9.2 15.0 23.6 12.2 65.5 14.5 59.4 7.6 13.5 31.5 14.6 18.5 17.9 98.4 155.2 83.3 111.0 30.0 41.3 61.0 42.3 36.5 57.0 65.8 84.2 72.1 102.8 33.7 47.0 115.5 117.1 63.8 64.3 33.1 46.2 109.4 80.6 136.3 72.7 7.2 63.2 78.0 27.4 16.7 82.3 29.0 18.6 31.0 147.1 65.0 111.6 64.5 250.2 119.1 245.3 179.5 48.5 94.7 163.5 123.4 86.4 31.7 54.9 83.5 115.6 43.7 126.9 20.8 59.8 83.9 165.8 29.1 54.2 205.1 126.8 102.3 85.2 70.6 108.9 54.6 155.1 199.8 31.5 60.2 44.4 42.8 78.6 34.3 71.0 49.6 45.6 94.3 65.1 48.9 42.3 16.2 39.4 66.8 211.5 75.5 45.7 13.7 16.6 14.6 18.0 15.4 13.6 16.1 14.1 15.6 15.0 14.5 17.9 13.0 6.4 7.5 1.0 34.2 40.1 26.5 22.6 14.8 11.2 25.3 39.0 16.8 10.0 13.7 11.0 4.2 38.5 46.1 39.6 19.6 24.3 54.7 14.9 24.3 12.8 7.8 111.7 0.5 37.4 80.0 29.6 13.7 10.7 61.0 32.4 7.9 5.2 89.4 0.0 0.5 35.7 32.6 46.2 86.7 121.2 22.1 52.6 46.2 0.0 47.1 27.4 47.4 1.0 4.3 20.4 18.4 18.8 33.1 21.5 17.3 14.1 13.0 7.9 32.9 27.5 32.4 70.2 54.8 41.0 37.1 23.7 37.3 13.7 45.1 27.3 NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2 component of NDC80 kinetochore complex" Q9BZD4 1 163266576-163355764 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 28.4;lymphoid tissue: 26.0;testis: 53.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 60.8;Spermatocytes: 208.2;Spermatogonia: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA059692: AB_2684103, HPA076604: " "unprognostic (9.41e-2)" "unprognostic (2.61e-1)" "unprognostic (2.56e-1)" "unprognostic (5.32e-3)" "unprognostic (6.20e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.04e-5)" "prognostic unfavorable (9.16e-4)" "prognostic unfavorable (4.83e-4)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (3.70e-2)" "unprognostic (0.00e+0)" "unprognostic (9.79e-2)" "unprognostic (7.88e-2)" "unprognostic (2.69e-1)" "unprognostic (5.96e-2)" 0.8 0.6 0.5 6.9 0.8 28.4 1.2 0.5 0.8 1.0 0.4 4.2 4.3 1.1 0.3 5.8 0.4 1.0 0.3 0.6 0.6 0.3 0.7 0.9 18.2 0.9 0.8 0.4 0.2 0.6 0.2 4.7 0.9 0.4 5.3 1.5 0.9 0.3 0.1 4.1 4.3 2.3 0.7 3.6 2.6 53.5 0.8 26.0 0.5 0.2 16.7 1.8 1.8 1.0 90.8 30.8 80.5 33.9 2.5 8.1 43.6 55.9 39.3 88.9 77.3 23.7 77.7 77.4 45.5 22.6 37.0 51.6 49.6 21.0 111.5 81.4 35.6 30.3 34.8 34.4 0.3 53.0 60.2 1.0 2.0 45.0 31.6 16.8 41.1 74.5 58.1 103.9 85.0 17.6 97.3 70.6 43.9 66.1 47.0 65.0 70.3 68.4 25.3 12.4 59.9 68.9 29.9 32.2 30.6 49.7 49.3 109.5 29.4 65.9 73.8 50.1 115.1 73.9 111.5 148.9 22.0 42.9 74.7 1.4 0.1 1.3 1.2 0.0 0.5 0.6 1.8 1.2 0.2 0.7 1.2 1.0 0.4 1.8 0.1 0.3 4.3 0.4 0.5 0.8 0.5 0.8 0.6 0.6 0.9 0.8 0.9 0.7 0.8 1.0 0.5 0.0 0.5 1.3 5.3 5.9 1.9 4.2 1.2 1.2 1.3 2.7 0.9 0.0 3.3 0.0 0.0 21.7 3.6 2.6 0.0 0.8 17.7 2.5 2.5 1.8 0.0 60.8 1.1 0.2 29.7 3.4 5.6 3.0 4.5 18.3 3.3 0.4 14.0 0.0 1.4 3.3 0.0 5.2 3.6 21.4 2.5 3.1 0.0 1.0 0.9 2.0 6.2 0.5 3.6 0.2 0.1 2.2 17.8 0.8 0.9 0.2 0.7 2.3 6.6 0.9 4.2 208.2 40.3 10.6 2.4 4.0 5.0 1.7 9.0 3.8 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 ORC1 "HSORC1, ORC1L, PARC1" ENSG00000085840 "Origin recognition complex subunit 1" Q13415 1 52372829-52404423 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 29.0;lymphoid tissue: 11.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.5;Early spermatids: 5.6;Erythroid cells: 14.1;Extravillous trophoblasts: 9.9;Plasma cells: 6.3;Spermatogonia: 6.5" "Cancer enhanced" "Detected in many" "testis cancer: 15.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027439, HPA027450" Approved Supported Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027439: , HPA027450: AB_10602041" "unprognostic (3.28e-1)" "unprognostic (4.42e-3)" "prognostic favorable (1.74e-5)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (3.77e-3)" "prognostic unfavorable (3.69e-4)" "unprognostic (3.86e-2)" "unprognostic (2.70e-3)" "unprognostic (8.39e-2)" "unprognostic (1.25e-10)" "unprognostic (4.56e-3)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.57e-2)" 0.4 0.6 0.2 3.5 0.1 29.0 1.1 0.6 0.2 0.6 0.0 3.4 1.7 0.6 0.1 2.7 0.3 0.4 0.2 0.1 0.2 0.5 0.6 0.6 6.7 0.3 0.0 0.5 0.3 0.3 0.3 1.9 0.2 0.4 4.0 1.0 0.6 0.1 0.5 2.0 2.3 0.9 0.0 2.0 1.0 5.2 0.2 11.6 0.3 0.1 7.7 0.9 1.0 0.3 19.3 20.8 33.0 21.7 0.8 2.7 31.8 13.5 12.2 38.9 40.0 25.8 10.7 44.2 11.6 8.5 17.8 25.9 48.9 16.9 33.8 19.0 28.1 53.2 30.2 25.8 0.2 71.9 29.2 1.4 0.8 38.1 4.3 2.7 11.7 27.6 63.0 20.9 12.8 14.4 56.9 34.0 73.1 11.7 29.5 60.2 51.3 43.1 6.8 25.0 18.5 15.6 31.0 18.8 10.3 30.5 10.2 28.7 5.4 15.8 22.5 24.9 34.0 10.9 31.1 54.4 15.6 52.6 19.5 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.4 0.4 0.6 0.8 0.1 0.3 0.4 3.4 0.2 0.0 1.2 0.3 0.2 0.1 0.6 0.2 0.1 0.2 0.3 0.0 0.2 0.0 0.2 0.3 0.6 0.0 0.0 0.3 1.7 0.9 0.3 0.4 1.2 0.7 0.7 1.1 0.5 0.0 0.1 0.0 0.0 5.5 0.7 1.2 0.0 0.3 5.6 0.5 0.6 0.5 0.0 14.1 0.7 0.2 9.9 0.7 0.5 0.6 0.0 2.8 0.0 0.2 2.9 0.0 0.7 1.3 0.0 0.3 0.4 3.8 0.6 0.6 0.0 1.0 0.3 0.2 0.0 0.5 0.5 0.2 0.8 0.4 6.3 0.2 0.2 3.9 0.1 0.9 0.0 0.6 0.7 4.1 6.5 2.5 1.1 1.8 1.1 0.9 3.7 0.4 ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;lymphoid tissue: 7.4;testis: 9.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 56.7;Spermatocytes: 102.6;Spermatogonia: 108.9;Theca cells: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB016330: AB_670295, HPA072587: AB_2686537" "unprognostic (3.47e-2)" "unprognostic (8.99e-3)" "unprognostic (2.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-2)" "unprognostic (3.15e-6)" "unprognostic (1.36e-2)" "prognostic unfavorable (3.53e-4)" "prognostic favorable (1.48e-4)" "unprognostic (1.50e-4)" "unprognostic (3.97e-2)" "unprognostic (3.90e-14)" "unprognostic (2.08e-1)" "unprognostic (4.24e-1)" "unprognostic (2.79e-1)" "unprognostic (5.98e-2)" 0.3 0.7 2.0 2.2 1.6 10.3 0.6 1.5 1.9 0.7 1.0 1.7 1.5 0.8 1.1 4.1 0.4 0.6 1.5 1.9 1.8 0.4 0.9 0.6 7.4 1.5 1.9 0.4 0.3 0.7 0.6 3.3 1.7 0.3 1.9 0.3 0.7 0.2 0.1 1.1 1.5 1.0 1.6 2.4 0.8 9.6 1.8 6.2 0.5 0.3 7.3 1.2 1.3 1.8 28.6 27.4 43.7 33.9 5.4 6.8 31.6 54.2 20.2 59.3 30.9 39.3 18.0 35.6 27.1 10.5 29.1 29.9 57.9 15.1 50.4 17.2 46.4 27.9 13.2 40.1 6.6 46.5 23.7 1.8 2.6 32.4 17.1 9.3 20.0 30.1 36.0 17.4 35.9 26.9 65.6 60.7 48.1 20.7 76.0 78.6 80.6 35.8 14.9 9.8 52.2 30.4 24.5 29.8 18.1 34.9 15.6 37.9 11.6 53.7 34.6 33.6 51.8 12.5 18.9 123.2 22.2 29.5 40.1 0.0 0.3 0.3 0.9 0.7 0.4 0.7 0.5 0.5 0.6 1.4 0.8 0.3 0.0 0.8 0.8 1.0 1.2 0.7 2.0 1.6 1.5 1.9 1.9 1.8 1.5 1.9 1.7 1.6 1.8 1.8 1.6 3.2 14.5 1.0 8.8 6.6 2.2 3.6 8.6 6.6 4.1 5.8 3.7 1.5 6.3 5.5 4.2 39.3 6.0 9.5 1.9 2.5 13.2 6.5 7.5 4.3 1.8 45.4 6.3 0.7 40.9 8.0 7.1 9.4 1.3 56.7 0.7 9.9 15.7 11.8 2.7 12.4 6.1 3.8 11.9 8.9 2.8 7.7 33.8 2.8 1.2 2.5 2.1 0.0 2.0 2.1 1.4 3.4 18.5 2.6 2.3 1.0 10.7 10.2 0.0 5.1 7.3 102.6 108.9 16.9 6.0 10.9 7.5 47.5 14.4 2.7 OTUD3 "DUBA4, KIAA0459" ENSG00000169914 "OTU deubiquitinase 3" Q5T2D3 1 19882395-19912945 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028543, HPA028544" Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Intermediate filaments" "HPA028543: AB_10599302, HPA028544: AB_10602277" "unprognostic (6.45e-3)" "unprognostic (9.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" "unprognostic (3.16e-3)" "unprognostic (1.70e-3)" "unprognostic (3.15e-3)" "unprognostic (4.99e-2)" "unprognostic (1.09e-1)" "unprognostic (8.81e-2)" "unprognostic (4.68e-2)" "unprognostic (1.08e-1)" "unprognostic (9.83e-2)" "unprognostic (1.94e-1)" "unprognostic (7.28e-2)" "unprognostic (2.21e-2)" 3.3 5.7 4.8 3.3 5.0 6.4 4.7 5.2 5.9 6.2 2.2 6.4 5.0 7.7 6.0 3.8 5.6 3.3 3.4 4.9 3.2 4.6 3.1 4.9 3.6 2.8 3.1 6.7 4.6 4.1 5.5 2.4 2.8 5.9 3.8 9.3 3.9 4.1 4.9 6.4 5.8 5.6 2.2 4.8 4.8 10.7 3.6 3.7 3.9 4.3 3.0 4.5 4.9 5.2 5.8 2.2 9.5 11.4 4.0 3.5 9.3 6.1 3.5 3.0 3.0 10.2 5.4 9.2 4.8 13.5 2.2 5.6 8.9 3.5 5.9 6.0 11.9 8.8 13.4 7.2 2.2 6.5 7.8 2.9 3.4 4.8 6.2 6.4 4.1 9.2 6.3 3.8 5.3 3.2 5.0 6.5 4.5 4.6 5.6 11.5 24.2 3.4 5.1 6.3 8.4 5.9 4.4 3.5 4.6 9.2 5.2 4.8 5.0 7.3 9.3 8.2 5.3 4.4 4.0 5.6 5.1 8.6 3.4 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.3 0.3 0.1 0.1 0.0 0.1 0.2 0.0 4.8 5.0 5.2 5.9 4.9 3.2 2.8 3.1 2.8 2.2 3.6 5.2 5.0 16.0 7.5 11.4 5.6 14.1 5.9 2.4 4.6 14.9 10.2 9.1 4.7 4.3 2.0 9.2 16.7 2.7 6.5 4.7 0.0 5.1 16.0 11.7 7.8 5.1 12.0 6.1 32.6 4.5 5.4 7.0 5.1 8.3 1.3 16.4 7.9 2.2 1.9 26.9 28.5 7.0 4.1 2.6 8.9 16.4 5.6 5.2 5.4 6.5 4.1 8.9 5.2 21.1 16.6 5.0 6.7 6.0 8.6 9.8 4.7 4.2 9.7 15.5 6.6 7.8 6.1 23.5 21.4 5.7 8.8 2.5 7.0 4.7 7.0 4.8 PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035895, HPA041538" Approved Approved Cytosol Yes No 490000 "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA035895: AB_10669660, HPA041538: AB_2677540" "unprognostic (2.59e-3)" "unprognostic (7.90e-3)" "unprognostic (3.84e-3)" "unprognostic (2.88e-2)" "unprognostic (9.85e-2)" "unprognostic (2.82e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.07e-3)" "unprognostic (1.23e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.48e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.11e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.16e-1)" 24.5 40.2 22.7 40.1 26.7 46.8 54.6 28.3 25.0 29.3 21.6 42.8 32.1 29.7 22.1 36.3 35.4 17.8 19.7 20.3 27.8 42.7 109.7 14.1 51.3 26.0 30.1 30.7 21.7 39.5 17.7 45.9 26.1 31.0 54.7 30.4 26.4 25.8 32.4 37.6 30.8 35.7 25.6 18.3 20.7 29.5 26.8 56.4 32.4 24.1 64.5 37.4 25.4 27.2 239.3 175.3 354.3 220.6 74.3 166.1 304.0 201.7 145.1 282.5 276.0 280.5 275.7 548.0 228.3 136.0 154.1 143.6 565.5 293.0 480.8 110.4 198.8 298.7 259.5 313.4 141.8 537.1 127.6 141.9 207.9 301.0 225.0 155.7 235.4 308.6 524.7 198.5 246.8 159.3 621.5 267.2 407.5 454.8 216.5 496.2 151.7 361.5 268.4 164.5 378.8 226.4 198.6 273.7 124.3 287.2 181.2 169.8 127.7 222.6 290.1 221.8 419.0 139.1 128.2 571.1 234.8 385.2 251.0 6.0 5.2 0.4 5.2 8.7 15.0 17.8 14.4 9.2 15.3 11.0 17.4 15.5 1.1 15.9 6.9 17.0 11.2 8.7 22.7 26.7 28.3 25.0 20.3 27.8 26.0 30.1 26.1 25.6 26.8 27.2 16.4 22.4 22.9 17.0 35.7 56.6 71.9 66.0 54.1 27.4 35.8 37.5 23.3 50.1 32.3 33.1 6.2 134.4 15.3 20.5 37.2 45.0 69.4 15.2 49.1 25.1 24.7 80.8 9.1 26.3 157.5 34.2 15.3 23.3 21.0 69.1 13.2 78.7 51.5 28.6 14.6 41.0 34.6 16.1 17.2 10.6 29.8 16.1 17.8 6.5 20.2 14.0 6.2 13.0 12.2 27.4 18.6 23.3 48.1 81.7 15.9 47.7 17.9 24.6 0.0 31.3 29.2 40.0 50.3 53.1 50.4 54.6 16.8 66.4 69.7 48.9 PARPBP "C12orf48, FLJ20641, PARI" ENSG00000185480 "PARP1 binding protein" Q9NWS1 12 102120183-102197520 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.3;lymphoid tissue: 7.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 20.0;Spermatogonia: 17.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039677 Approved Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039677: AB_10673426" "unprognostic (7.84e-3)" "unprognostic (1.34e-2)" "unprognostic (4.54e-3)" "unprognostic (3.03e-2)" "unprognostic (1.84e-1)" "unprognostic (3.03e-1)" "unprognostic (1.30e-5)" "unprognostic (2.52e-3)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.38e-1)" "unprognostic (3.95e-3)" "unprognostic (2.83e-1)" "unprognostic (5.61e-8)" "unprognostic (3.50e-3)" "unprognostic (2.34e-1)" "unprognostic (9.16e-3)" "unprognostic (6.14e-2)" 0.8 0.6 0.2 3.1 0.2 9.3 1.8 0.3 0.4 1.2 0.1 3.0 2.3 1.2 0.5 3.6 0.6 1.1 0.4 0.3 0.4 0.8 0.6 0.6 4.2 0.3 0.4 0.7 0.2 0.3 0.2 2.3 0.3 1.0 3.8 0.2 0.9 0.9 0.4 1.9 2.7 1.7 0.3 1.2 1.8 3.9 0.3 7.5 0.5 0.3 5.1 1.9 1.1 0.3 13.5 27.2 23.6 13.7 3.8 3.4 16.7 19.9 11.0 32.0 27.9 14.8 10.4 25.4 11.4 7.8 16.2 14.5 38.5 11.7 34.2 25.7 22.6 31.9 15.7 13.9 1.1 33.5 9.1 3.3 2.8 22.3 14.4 8.3 21.6 18.9 31.0 15.3 21.1 10.7 30.5 31.1 31.7 17.8 26.6 20.4 38.9 16.7 10.3 21.1 15.9 14.7 13.8 16.6 11.8 24.0 27.1 12.1 8.5 16.5 15.7 20.2 25.3 11.3 24.8 22.8 11.4 33.7 22.4 2.6 0.4 1.0 0.5 0.6 0.1 1.1 0.9 0.8 0.7 0.7 0.5 0.6 0.0 0.5 0.4 0.7 1.8 0.7 0.2 0.2 0.3 0.4 0.3 0.4 0.3 0.4 0.3 0.3 0.3 0.3 1.1 0.0 0.0 2.9 4.3 3.7 1.5 3.6 0.6 1.9 2.4 2.4 0.7 1.5 2.5 1.8 0.0 11.3 2.3 1.5 5.9 1.6 2.5 3.0 11.6 2.5 1.8 20.0 4.1 1.3 13.9 4.8 6.1 3.0 5.7 15.0 2.2 0.1 6.5 3.3 5.3 3.1 10.2 5.7 4.3 2.6 1.2 3.1 0.0 3.7 1.7 0.2 2.1 3.5 4.1 1.2 0.8 0.4 14.2 0.7 1.3 1.8 1.4 0.9 0.0 1.1 2.8 16.0 17.7 9.8 1.6 3.6 4.1 9.3 7.8 1.6 PCLAF "KIAA0101, NS5ATP9, OEATC-1, p15(PAF), PAF15" ENSG00000166803 "PCNA clamp associated factor" Q15004 15 64364304-64387687 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 128.6;lymphoid tissue: 73.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.2;Extravillous trophoblasts: 160.2;Granulosa cells: 48.8;Hofbauer cells: 110.2;Syncytiotrophoblasts: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 4 "T-reg: 23.6" "Lineage enriched" "Detected in many" 4 "T-cells: 23.6" "Low cell line specificity" "Detected in all" HPA047929 Supported Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA047929: AB_2680215" "unprognostic (5.34e-2)" "unprognostic (1.36e-3)" "unprognostic (9.39e-2)" "unprognostic (1.28e-1)" "unprognostic (4.16e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (4.38e-3)" "unprognostic (1.91e-3)" "unprognostic (7.26e-2)" "unprognostic (2.56e-3)" "unprognostic (9.65e-2)" "prognostic unfavorable (9.77e-15)" "unprognostic (5.59e-2)" "unprognostic (2.05e-1)" "unprognostic (8.65e-2)" "unprognostic (3.22e-1)" 2.1 1.4 0.9 22.9 1.0 128.6 3.9 1.4 1.1 1.7 0.8 19.0 14.7 4.5 1.2 15.2 1.3 2.5 0.4 0.9 0.6 1.2 3.6 2.5 49.5 1.0 0.8 0.4 1.9 0.8 0.5 8.7 0.9 2.0 22.6 0.3 2.3 0.3 0.4 6.7 15.8 5.0 0.5 7.4 8.1 1.1 1.0 73.8 2.2 0.1 47.1 7.9 4.9 1.9 212.6 165.8 154.4 140.8 15.9 60.9 134.4 146.2 84.8 185.4 276.4 198.4 202.1 343.7 46.4 57.4 64.8 153.6 340.7 83.1 235.3 192.5 124.8 352.5 202.5 209.8 1.5 285.3 153.8 20.0 7.9 156.4 31.9 52.3 168.9 175.9 201.3 104.4 248.1 187.8 268.0 605.5 73.9 179.9 73.4 416.6 353.8 247.1 115.9 200.2 19.1 86.7 112.8 105.2 69.3 78.9 153.8 365.3 36.3 158.4 308.6 177.8 386.7 65.5 223.4 229.0 67.7 512.9 108.5 2.4 0.3 0.9 1.4 0.2 0.2 2.0 4.4 4.2 2.8 0.6 0.5 1.0 2.7 5.7 0.4 0.3 23.6 2.3 0.9 1.0 1.4 1.1 0.9 0.6 1.0 0.8 0.9 0.5 1.0 1.9 0.5 9.6 11.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 27.5 25.5 0.0 0.0 5.0 1.8 0.0 82.2 8.3 0.0 1.9 6.5 0.0 18.6 10.4 8.5 0.0 0.0 0.0 3.0 160.2 25.4 0.0 13.8 3.8 48.8 0.0 0.0 110.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 4.3 0.0 0.0 3.0 3.6 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.0 42.1 5.8 7.6 0.0 0.0 PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 383.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000148, HPA030521, HPA030522, HPA030523" Enhanced Enhanced Nucleoplasm No Yes 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000148: AB_628110, HPA030521: AB_10600218, HPA030522: AB_10602096, HPA030523: AB_10602199" "unprognostic (5.21e-2)" "prognostic favorable (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-1)" "unprognostic (5.60e-3)" "prognostic unfavorable (2.61e-4)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.89e-2)" "unprognostic (1.01e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.03e-6)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (7.11e-3)" "unprognostic (7.46e-2)" 31.2 47.2 23.2 85.2 26.0 383.2 51.0 26.8 29.7 41.5 26.8 89.0 70.7 38.1 30.9 81.2 39.1 34.8 30.6 23.0 24.4 43.7 55.3 37.5 168.8 25.1 24.0 37.7 32.8 42.4 25.1 69.8 26.0 32.2 93.7 94.1 40.3 38.3 27.9 62.8 72.9 47.9 26.8 54.0 53.9 62.3 23.3 219.9 42.0 26.8 137.3 51.0 42.3 30.0 769.1 591.4 585.0 253.7 136.1 126.6 409.5 491.6 288.3 453.7 640.0 465.3 594.2 773.4 155.7 177.5 395.2 558.8 350.7 594.4 413.2 231.7 386.8 543.7 207.8 1098.3 57.8 753.7 233.0 92.6 138.2 387.2 91.7 95.3 263.3 503.6 493.9 631.2 449.7 278.3 1450.6 829.3 439.9 592.0 322.9 787.9 514.1 622.5 208.5 441.1 500.8 339.4 345.1 524.6 351.9 213.9 371.2 378.0 177.2 324.3 373.3 461.5 572.0 317.2 981.6 1313.9 145.9 707.4 426.2 5.0 23.2 18.5 36.5 23.3 45.7 33.5 45.7 37.1 32.6 29.2 41.6 37.3 7.7 43.6 24.7 29.9 48.1 36.7 23.2 26.0 26.8 29.7 23.0 24.4 25.1 24.0 26.0 26.8 23.3 30.0 32.4 44.8 26.0 2.9 40.6 67.7 44.4 121.4 44.3 42.1 27.5 45.2 14.5 21.5 60.5 58.8 27.1 171.5 44.3 42.9 60.7 51.6 176.0 30.2 21.4 34.8 19.9 189.0 4.3 39.6 175.6 38.7 21.9 27.7 22.7 53.1 29.6 27.1 96.7 32.0 5.9 53.9 75.3 24.2 33.4 109.1 36.1 32.7 37.4 3.7 47.6 74.0 23.7 4.0 13.5 28.3 20.3 40.3 56.6 23.3 33.3 46.1 44.1 97.1 52.6 29.2 46.1 149.1 101.1 65.5 49.7 66.4 48.6 29.6 84.5 40.4 PHF5A "bK223H9.2, INI, MGC1346, Rds3, SAP14b, SF3b14b, SF3B7" ENSG00000100410 "PHD finger protein 5A" Q7RTV0 22 41459717-41468692 "Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028885 Supported Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028885: AB_10602079" "unprognostic (4.38e-2)" "unprognostic (3.58e-1)" "unprognostic (2.12e-3)" "unprognostic (2.64e-2)" "unprognostic (1.07e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (3.02e-8)" "unprognostic (3.39e-3)" "unprognostic (3.97e-3)" "unprognostic (4.46e-2)" "unprognostic (6.95e-3)" "unprognostic (2.12e-1)" "unprognostic (5.25e-3)" "unprognostic (4.11e-2)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "unprognostic (6.91e-2)" 26.0 21.1 26.5 23.0 29.7 58.2 27.7 30.0 30.6 23.3 28.9 25.1 22.7 22.9 26.0 29.0 22.8 19.6 20.9 26.7 28.5 25.5 30.9 20.1 35.5 28.9 28.5 20.7 26.2 25.1 21.5 25.6 29.7 19.7 28.8 24.5 21.0 19.1 35.8 27.7 22.4 22.6 28.8 26.4 26.0 18.8 28.2 52.2 19.7 29.0 41.9 30.6 23.7 33.9 80.5 56.8 95.0 62.8 68.7 51.7 65.9 80.1 65.5 102.9 86.4 78.4 46.5 115.4 45.7 60.1 72.1 60.7 130.2 95.3 115.6 71.7 136.5 71.8 86.9 92.2 71.9 190.3 54.9 50.4 72.9 81.3 100.5 41.7 73.8 80.6 97.5 71.8 74.9 107.5 154.8 124.3 96.1 220.8 82.2 115.4 84.9 81.5 68.6 63.1 46.6 38.9 87.9 57.4 90.0 66.6 45.9 96.8 50.7 54.0 95.6 44.1 97.9 58.9 112.3 194.9 52.2 82.6 59.0 32.8 47.0 57.9 36.0 45.2 47.2 47.6 41.1 45.6 49.2 42.6 40.2 39.5 55.6 47.6 44.1 41.7 47.8 59.3 26.5 29.7 30.0 30.6 26.7 28.5 28.9 28.5 29.7 28.8 28.2 33.9 36.4 22.4 13.9 2.3 52.3 77.2 78.1 81.1 58.1 24.6 35.1 35.4 10.6 41.5 33.5 11.0 4.2 93.0 42.3 27.2 46.9 58.5 14.7 26.6 20.7 43.7 15.0 56.1 3.5 56.2 115.0 36.2 20.4 25.5 33.7 20.9 37.5 24.7 58.7 13.5 3.7 32.1 63.1 38.8 55.9 9.1 42.3 37.3 33.8 2.8 67.5 47.3 59.8 5.5 8.2 64.5 32.5 41.8 41.6 84.4 41.1 42.1 24.3 28.2 98.6 32.3 38.6 63.5 88.1 59.0 91.6 109.2 42.3 20.2 41.9 95.7 PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.8" "Cell type enhanced" "Detected in many" "Early spermatids: 21.3;Erythroid cells: 17.7;Granulosa cells: 15.1;NK-cells: 15.5;Theca cells: 18.3" "Cancer enhanced" "Detected in many" "testis cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB018701: AB_2164654" "unprognostic (1.99e-1)" "unprognostic (6.11e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (8.66e-4)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (6.68e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (0.00e+0)" "unprognostic (2.96e-3)" "unprognostic (1.78e-1)" "unprognostic (9.61e-2)" "unprognostic (5.95e-2)" 0.7 1.0 0.8 2.6 0.8 3.8 0.4 0.7 1.3 0.9 0.7 2.4 1.9 0.8 0.1 3.1 0.7 0.8 0.9 0.7 1.2 0.6 0.6 1.0 4.6 1.4 1.0 0.4 0.2 0.2 0.5 0.9 1.1 1.7 1.0 0.1 0.6 0.7 0.3 1.0 2.6 1.2 0.9 4.8 1.8 2.5 1.2 3.6 0.5 0.1 3.3 1.5 1.4 0.8 7.7 8.7 21.1 8.6 3.7 4.3 7.8 7.4 3.9 7.3 5.6 14.0 12.6 9.3 3.0 3.6 6.8 20.9 21.8 6.2 2.7 14.8 8.0 10.8 28.5 10.2 1.9 4.3 8.4 2.5 0.0 3.2 2.6 1.8 7.5 13.6 7.2 18.0 7.0 6.7 4.7 17.9 17.2 9.7 6.0 9.7 7.0 13.0 4.1 4.3 8.7 5.6 5.7 6.3 3.3 9.2 7.0 4.7 5.2 4.4 22.6 7.0 14.0 14.3 14.3 9.0 4.2 18.8 6.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.8 0.7 1.3 0.7 1.2 1.4 1.0 1.1 0.9 1.2 0.8 1.2 0.0 1.1 3.6 6.5 1.9 0.8 0.6 0.0 0.5 0.6 0.6 1.9 0.0 0.1 0.0 0.0 5.1 7.5 3.2 0.0 0.0 21.3 0.4 4.4 2.3 0.0 17.7 2.6 0.0 6.5 5.6 3.6 0.7 0.0 15.1 5.3 0.5 5.8 0.0 1.0 2.4 0.0 5.1 2.0 2.3 1.5 4.5 0.0 1.9 0.1 0.8 15.5 3.5 0.1 0.2 0.1 2.2 9.7 1.1 0.2 0.1 0.1 1.2 6.6 4.2 3.5 0.8 2.0 1.6 1.0 1.1 7.5 18.3 6.2 1.3 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.6;testis: 56.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.0;Extravillous trophoblasts: 52.0;Plasma cells: 22.9;Spermatocytes: 114.7;Spermatogonia: 46.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 1.1 1.0 0.4 6.8 0.5 27.6 0.6 1.6 1.4 2.2 0.2 3.9 2.8 0.6 0.3 11.5 0.4 0.6 0.9 0.5 0.2 0.9 1.6 2.0 8.0 0.7 0.6 0.3 1.8 0.1 1.0 3.1 0.8 1.0 1.3 17.4 1.9 0.1 2.4 4.4 4.0 1.0 0.5 5.6 3.3 56.9 0.7 9.6 0.5 0.0 4.5 0.7 3.3 0.8 84.2 57.0 22.0 31.2 0.3 0.9 64.0 65.5 15.1 40.0 38.4 45.0 49.3 54.2 29.2 7.9 24.2 106.7 15.7 20.7 7.2 71.7 56.7 27.9 52.7 40.0 0.0 31.2 73.6 0.7 1.8 24.0 6.5 5.0 8.4 57.6 80.6 87.0 13.5 127.5 83.6 88.0 37.9 39.3 34.4 93.7 51.2 100.7 7.8 17.7 42.6 46.7 31.9 77.7 23.9 12.1 44.7 56.9 7.7 53.2 69.7 77.3 68.0 67.6 54.2 94.0 19.4 40.0 61.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.3 0.4 0.5 1.6 1.4 0.5 0.2 0.7 0.6 0.8 0.5 0.7 0.8 0.0 0.0 1.1 0.0 1.9 2.5 1.3 2.1 0.6 0.4 1.5 1.3 0.6 1.5 1.6 1.8 6.2 16.0 1.3 5.0 0.0 0.8 20.0 0.6 0.8 0.8 1.8 29.0 0.4 0.6 52.0 2.5 3.1 1.9 0.0 4.5 0.0 0.4 11.8 0.0 0.2 3.6 6.1 2.1 1.8 8.6 0.3 1.9 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.6 0.3 0.4 22.9 0.7 0.3 0.1 0.2 7.1 0.0 0.1 2.6 114.7 46.1 11.2 0.6 7.4 4.2 0.5 8.6 2.0 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.0;lymphoid tissue: 43.9;testis: 33.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.3;Early spermatids: 123.7;Erythroid cells: 38.3;Extravillous trophoblasts: 55.9;Spermatocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 5.6" "Lineage enriched" "Detected in many" 5 "T-cells: 5.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051638, HPA053229" Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA051638: AB_2681561, HPA053229: AB_2682084" "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (2.70e-7)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 1.4 1.5 2.3 13.4 2.3 32.0 1.5 2.5 3.2 2.3 2.0 9.6 10.4 1.2 0.4 13.9 1.0 1.4 1.0 2.3 2.1 1.4 1.9 1.9 27.8 2.3 2.3 1.3 1.1 0.2 1.2 6.4 2.2 1.2 10.1 1.2 2.4 0.3 1.0 5.7 9.2 4.0 2.0 9.1 6.2 33.1 2.5 43.9 0.9 0.4 30.0 2.8 4.0 2.8 199.9 207.5 166.2 90.9 5.2 11.7 92.8 111.0 74.5 172.5 127.0 184.3 131.0 99.1 56.3 76.5 90.1 112.8 229.5 93.5 206.1 139.5 128.0 125.2 163.4 257.1 1.7 147.5 133.7 4.8 5.2 124.7 125.2 21.6 127.9 127.5 200.7 133.9 134.8 187.8 139.8 151.4 189.5 82.1 103.5 217.2 111.7 160.0 49.3 43.9 94.3 65.3 126.8 88.9 55.8 94.4 114.4 92.1 65.1 82.7 102.7 79.9 194.1 93.2 156.8 173.6 69.3 127.7 137.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.3 0.3 0.0 0.0 0.0 0.4 0.9 0.0 0.0 5.6 1.4 2.3 2.3 2.5 3.2 2.3 2.1 2.3 2.3 2.2 2.0 2.5 2.8 0.6 3.2 0.0 3.3 7.6 1.3 1.2 6.5 0.0 1.4 1.7 2.3 0.6 0.0 1.4 0.0 4.2 32.3 0.4 5.5 0.0 0.8 123.7 3.4 1.3 2.5 0.0 38.3 3.1 0.8 55.9 4.7 10.2 1.8 1.3 19.9 3.3 1.1 20.8 0.0 2.3 7.3 4.1 6.9 3.2 13.9 1.2 7.2 0.0 2.8 0.4 1.1 0.0 1.5 2.3 1.2 0.3 0.7 23.0 2.0 1.5 0.1 1.3 1.3 0.0 2.3 6.1 79.5 13.5 12.2 1.8 3.8 2.5 1.2 17.9 2.0 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880893-127899224 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 22.6;lymphoid tissue: 14.4;testis: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 65.9;Late spermatids: 87.5;Spermatocytes: 53.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centrosome, Cytosol" "HPA017327: AB_2669584, HPA035026: AB_10602080, HPA043198: AB_2732504" "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favorable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.0 1.1 0.4 4.9 0.5 22.6 2.0 0.2 0.7 0.9 0.1 3.5 2.8 1.5 0.6 3.2 1.3 1.1 0.5 0.5 0.6 0.6 0.8 0.9 7.4 0.5 0.5 1.0 0.4 0.6 0.2 3.6 0.4 0.9 4.3 2.1 0.9 0.9 0.1 2.3 2.9 1.8 0.4 1.6 2.0 22.6 0.6 14.4 0.9 0.7 7.3 1.3 1.4 0.4 26.1 12.1 44.3 22.9 1.5 4.2 20.1 24.9 17.6 32.4 33.3 17.0 26.1 34.9 9.0 13.9 26.3 16.7 31.6 19.9 49.6 27.4 13.1 31.6 20.0 16.0 0.5 45.2 35.9 1.4 2.0 29.7 13.6 5.9 25.3 26.3 37.5 45.2 27.6 18.2 69.9 20.1 20.7 26.3 13.6 36.0 30.9 12.1 10.8 16.4 24.4 20.0 15.8 14.2 7.6 18.7 11.5 19.3 11.0 25.3 24.4 17.4 31.4 23.1 27.4 49.0 13.0 33.7 28.7 0.0 0.1 0.4 0.4 0.2 0.3 0.1 0.5 0.5 0.2 0.2 0.1 0.6 0.0 0.4 0.1 0.1 1.2 0.2 0.4 0.5 0.2 0.7 0.5 0.6 0.5 0.5 0.4 0.4 0.6 0.4 1.6 0.0 0.6 0.0 1.6 1.7 0.9 1.7 1.2 1.8 1.0 0.9 0.9 0.0 0.6 1.8 0.0 6.0 1.9 2.0 0.0 0.6 65.9 4.7 1.0 1.0 2.4 19.6 0.8 0.4 12.9 1.6 4.1 2.0 1.3 7.5 0.4 0.5 3.7 0.0 0.8 3.3 6.1 1.3 0.6 87.5 2.8 1.5 0.0 1.0 1.2 1.1 1.0 1.0 1.2 0.1 0.5 0.4 8.7 0.7 0.5 0.6 3.7 0.8 0.0 0.4 3.6 53.5 13.4 6.8 0.9 3.8 2.1 0.8 4.5 1.7 POC1A "DKFZP434C245, WDR51A" ENSG00000164087 "POC1 centriolar protein A" Q8NBT0 3 52075226-52154690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Dwarfism, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.8;testis: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Extravillous trophoblasts: 33.8;Late spermatids: 73.4;Spermatocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040600 Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA040600: AB_10672837" "unprognostic (2.68e-1)" "unprognostic (7.17e-2)" "prognostic favorable (1.78e-4)" "unprognostic (5.08e-2)" "unprognostic (3.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-3)" "unprognostic (2.41e-2)" "unprognostic (7.23e-3)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (9.43e-7)" "unprognostic (9.90e-3)" "unprognostic (1.96e-1)" "unprognostic (3.62e-2)" "unprognostic (2.32e-2)" 1.4 4.1 1.5 4.0 1.5 11.1 2.2 1.4 1.8 1.5 1.1 5.9 4.8 1.0 1.0 4.7 1.7 1.1 1.4 1.7 1.6 2.1 5.2 1.9 5.4 1.9 1.6 0.7 0.9 1.1 0.7 4.1 1.8 1.3 6.0 0.4 1.3 1.0 1.5 2.6 4.0 2.9 1.5 2.8 2.8 17.6 1.6 12.8 1.0 1.0 7.0 2.0 1.8 1.8 30.1 25.2 25.0 33.5 5.1 6.5 33.9 30.0 28.7 62.8 48.7 22.1 31.0 31.3 8.8 23.9 48.6 18.3 38.0 33.9 45.3 26.0 16.0 21.4 26.3 23.9 1.4 24.5 13.0 3.6 7.3 49.6 25.9 8.7 29.0 46.2 18.8 32.9 37.5 23.8 45.6 44.2 19.1 33.7 41.0 19.6 19.7 30.0 14.2 21.0 11.6 16.7 24.0 23.7 18.3 26.0 29.2 45.7 9.7 28.6 27.6 46.3 49.3 27.8 49.1 26.6 19.2 42.6 29.1 0.0 1.6 0.0 1.2 2.2 0.1 0.9 0.8 0.4 1.9 0.5 0.7 0.4 0.5 1.4 1.6 1.9 2.6 1.1 1.5 1.5 1.4 1.8 1.7 1.6 1.9 1.6 1.8 1.5 1.6 1.8 0.9 0.0 1.3 0.3 2.5 1.7 1.6 4.7 0.0 0.7 2.1 2.2 0.7 0.0 1.4 1.8 0.0 21.8 0.9 4.4 0.0 1.8 47.9 4.5 1.0 2.9 1.8 15.6 2.3 3.0 33.8 3.4 2.0 1.5 0.0 11.3 1.8 4.2 12.9 1.7 1.4 5.4 0.0 2.6 3.4 73.4 1.2 2.6 1.8 1.9 2.7 0.8 1.0 0.0 2.7 2.1 2.2 0.4 12.9 1.3 3.0 3.2 4.2 0.0 0.0 1.1 3.4 40.1 21.2 4.9 1.8 7.5 1.6 4.4 8.4 2.1 POLA2 FLJ21662 ENSG00000014138 "DNA polymerase alpha 2, accessory subunit" Q14181 11 65261920-65305589 "Metabolic proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.2;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA037570 Supported Supported Nucleoplasm,Cytosol NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA037570: AB_10672280" "unprognostic (2.28e-1)" "prognostic favorable (4.61e-4)" "unprognostic (1.67e-2)" "unprognostic (7.44e-2)" "unprognostic (5.20e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "unprognostic (1.15e-2)" "unprognostic (4.05e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (4.09e-8)" "unprognostic (1.60e-3)" "unprognostic (8.26e-2)" "unprognostic (8.16e-2)" "unprognostic (6.25e-3)" 3.3 2.6 1.9 5.3 2.9 6.9 3.5 4.8 3.3 4.5 1.7 5.3 3.6 5.0 3.3 4.5 3.8 1.8 2.9 1.9 1.5 3.5 3.7 3.5 10.0 4.5 2.8 5.1 3.3 3.2 1.9 2.1 3.7 3.0 4.9 3.6 4.2 3.1 3.1 5.1 4.2 4.1 3.1 5.7 3.8 5.2 2.6 15.9 3.3 3.4 13.2 3.2 3.2 7.0 32.6 21.9 47.3 20.4 3.7 3.6 19.5 25.6 15.9 64.4 43.3 6.9 24.0 48.1 20.4 11.0 35.5 18.9 38.8 25.1 61.1 21.3 14.7 32.4 39.4 10.4 0.9 33.5 25.6 3.7 2.9 47.4 8.5 10.3 14.6 20.2 30.2 25.3 44.4 34.9 62.6 13.2 38.6 16.1 16.2 33.4 29.9 40.7 14.1 21.8 32.5 18.1 14.9 15.9 7.9 29.7 28.6 14.1 3.9 25.4 18.7 19.8 16.0 12.0 14.7 45.0 14.9 18.8 33.7 10.0 5.2 2.3 3.8 3.2 4.5 3.9 4.2 4.2 7.4 3.9 3.5 3.1 1.4 3.8 1.7 5.9 4.6 5.3 1.9 2.9 4.8 3.3 1.9 1.5 4.5 2.8 3.7 3.1 2.6 7.0 2.6 0.0 3.4 1.0 5.1 1.7 4.2 5.7 2.2 2.2 3.0 2.3 2.9 7.2 3.7 5.5 2.1 15.6 4.3 3.0 3.9 5.3 2.7 1.8 2.9 3.7 3.0 23.2 4.3 3.4 19.0 7.7 5.6 2.5 0.0 11.0 5.3 2.1 9.7 3.3 3.6 3.5 2.0 2.8 3.7 4.0 7.5 5.3 0.0 12.2 8.0 2.2 5.2 1.5 8.7 4.9 2.2 7.5 10.4 3.4 1.7 2.0 3.2 5.4 6.6 19.6 5.0 23.7 17.7 4.3 1.4 7.3 5.5 4.0 6.3 3.7 POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418018 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 51.3;Spermatogonia: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004375: AB_675487, HPA046524: AB_2679684" "unprognostic (2.45e-1)" "unprognostic (7.02e-3)" "unprognostic (1.59e-1)" "unprognostic (4.35e-2)" "unprognostic (2.55e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.87e-6)" "unprognostic (4.12e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (5.08e-1)" "unprognostic (3.92e-3)" "unprognostic (4.01e-3)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (3.70e-2)" 5.6 5.1 3.2 9.2 3.7 26.3 6.3 4.5 3.8 7.6 2.5 8.9 5.4 8.4 0.4 10.7 6.5 2.1 5.8 2.7 2.7 6.5 6.4 9.5 11.2 5.1 3.7 7.1 7.9 2.3 4.7 5.9 4.1 6.1 2.2 1.9 7.4 2.6 5.6 9.2 10.1 2.3 3.5 12.8 6.2 13.3 4.1 11.0 9.8 1.5 5.2 5.9 7.7 4.4 52.1 77.9 27.9 22.4 3.0 2.8 45.6 34.0 9.6 30.0 34.9 42.4 39.2 84.6 19.4 7.1 13.9 45.1 27.4 25.1 6.8 64.4 145.0 66.1 73.0 54.6 3.7 67.0 57.7 6.4 7.1 26.1 6.5 6.0 14.2 58.2 77.4 54.3 9.1 40.6 92.2 110.6 48.7 25.3 55.4 105.4 62.2 67.7 7.4 44.9 39.3 38.6 33.0 35.9 8.8 10.1 21.1 50.7 17.4 21.4 70.7 22.0 56.5 60.0 91.3 76.3 21.2 66.9 20.8 1.3 4.3 1.5 4.3 5.6 4.0 6.0 4.0 3.5 3.9 5.4 4.0 3.9 0.6 4.2 6.9 7.1 3.1 4.0 3.2 3.7 4.5 3.8 2.7 2.7 5.1 3.7 4.1 3.5 4.1 4.4 3.5 3.2 3.9 0.7 8.7 6.4 2.3 3.5 3.4 4.0 4.3 5.3 3.4 2.8 3.8 3.7 6.2 19.2 3.8 12.2 0.0 4.8 1.9 2.8 1.6 3.4 7.2 15.2 1.2 4.0 15.0 4.1 3.1 3.0 0.0 9.5 1.1 2.2 15.1 0.0 0.9 7.4 0.0 5.7 5.3 1.9 3.1 5.8 5.4 1.0 4.8 1.2 6.2 1.5 2.2 4.7 51.3 5.3 10.6 2.8 6.3 2.8 3.0 4.3 0.0 3.5 4.0 11.5 25.6 5.5 5.3 7.7 5.4 3.4 14.3 1.3 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687376 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 46.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA058210: AB_2683639, HPA067385: AB_2685830" "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.0 2.9 0.2 6.1 0.2 24.7 6.0 4.1 1.1 6.4 0.3 7.3 6.5 5.4 2.1 7.0 6.2 3.1 4.3 1.6 0.0 3.0 8.6 5.0 7.2 0.3 0.1 7.8 6.5 2.6 2.7 5.3 0.3 6.4 6.3 2.4 6.1 3.3 7.5 13.2 8.5 3.7 0.1 16.2 8.0 16.2 0.5 15.7 4.7 3.0 7.1 6.1 6.2 0.3 25.3 33.3 48.7 22.0 10.2 7.6 39.9 26.0 11.7 30.3 21.8 38.3 14.5 28.7 10.2 14.1 11.6 33.6 35.4 16.7 18.8 13.3 41.2 45.4 45.7 15.2 1.9 37.2 24.9 5.5 6.0 31.8 10.5 8.1 10.8 35.1 53.4 15.7 14.9 33.3 61.8 46.8 36.9 9.3 18.5 48.0 27.6 13.0 6.9 40.8 40.6 22.0 30.0 22.7 4.7 23.4 35.0 19.1 9.9 26.5 24.7 20.6 25.9 20.3 14.5 44.8 14.7 26.3 19.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 4.1 1.1 1.6 0.0 0.3 0.1 0.3 0.1 0.5 0.3 3.2 0.0 6.7 7.5 4.0 5.7 3.8 3.0 4.0 8.7 7.8 6.7 6.9 1.5 1.6 1.8 0.0 8.8 5.6 18.8 0.0 2.3 8.2 3.2 3.8 4.9 7.2 14.9 13.6 3.3 10.8 5.1 11.2 6.8 2.5 16.2 8.9 10.5 13.2 0.0 7.6 9.1 2.0 6.9 5.4 9.7 6.8 2.9 5.4 4.7 1.6 2.6 2.1 3.5 2.9 2.6 6.0 3.4 6.3 4.0 4.1 1.0 1.9 6.1 26.3 7.0 6.1 46.6 18.2 5.8 7.7 4.0 5.8 2.9 10.9 2.8 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favorable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.1 0.2 0.0 1.6 0.1 6.0 0.4 1.0 0.2 0.2 0.0 1.2 1.2 0.2 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 2.0 0.0 0.3 0.0 0.0 1.4 0.9 0.4 0.0 0.8 0.5 2.2 0.0 4.5 0.0 0.0 2.3 0.3 0.5 0.0 18.2 12.1 10.2 7.2 0.9 1.2 9.2 8.5 3.2 9.7 12.9 9.8 6.6 21.5 3.7 4.6 11.7 14.0 12.2 5.4 16.4 6.3 6.7 13.8 8.0 6.1 0.1 15.1 12.1 0.2 0.4 8.9 5.4 1.7 4.9 7.9 9.3 15.9 10.3 7.1 13.7 8.8 9.7 5.5 5.9 11.4 12.2 7.6 3.1 10.3 5.5 5.0 9.8 5.2 3.4 8.8 4.8 14.8 3.8 8.6 11.2 3.4 11.1 8.0 6.9 21.8 4.1 11.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.6 0.7 0.9 0.5 0.6 0.0 0.9 0.6 0.6 1.6 0.0 2.0 0.0 0.0 3.1 0.6 1.6 0.0 0.1 0.4 0.9 1.0 0.5 0.0 16.4 9.5 0.0 3.3 1.2 4.6 1.0 0.0 12.6 0.0 0.2 2.3 0.0 7.8 1.6 2.0 1.3 1.2 0.7 0.3 1.7 0.0 1.0 0.6 0.4 0.0 1.5 1.3 0.2 1.2 0.0 12.2 0.5 0.2 0.1 2.4 0.2 0.0 0.1 1.0 6.8 3.4 4.9 0.1 0.3 1.8 0.9 3.2 0.8 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890547-60906585 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" NA NA 71000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB012448: AB_2170868, HPA038051: AB_2675807, HPA059070: AB_2683896" "unprognostic (5.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (4.11e-8)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (9.37e-3)" "unprognostic (9.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.70e-2)" "unprognostic (9.62e-2)" "unprognostic (7.12e-2)" "unprognostic (9.04e-2)" "unprognostic (3.41e-3)" 46.1 70.6 89.8 49.8 87.9 67.0 48.8 73.7 100.2 57.4 60.2 54.5 42.9 55.4 34.2 81.7 57.3 29.4 47.9 91.3 94.1 50.4 77.2 34.6 64.1 92.0 80.7 66.6 69.4 79.8 79.3 42.9 92.9 62.1 51.8 46.1 56.5 48.2 75.2 80.3 49.5 47.9 75.6 54.3 54.3 30.5 81.1 78.5 43.4 38.9 73.7 58.7 55.9 84.5 197.5 147.0 161.8 116.2 92.7 80.8 155.6 102.4 137.5 200.2 149.0 162.7 141.1 280.5 145.2 98.2 120.2 179.0 229.2 184.6 153.4 207.0 153.4 232.4 111.3 184.9 134.2 308.6 161.1 86.3 137.0 154.4 171.9 58.7 158.7 167.4 248.2 155.3 99.5 270.6 328.9 249.5 292.6 150.5 197.7 285.8 165.5 227.5 101.7 127.5 142.3 172.9 126.6 208.3 178.0 73.1 225.8 170.2 101.9 89.6 147.2 161.8 171.2 147.2 223.3 287.9 111.6 208.6 138.6 4.2 7.8 2.0 2.4 3.8 1.7 0.9 1.8 1.7 3.6 2.4 2.2 2.0 0.5 1.8 2.3 3.9 1.7 1.0 89.8 87.9 73.7 100.2 91.3 94.1 92.0 80.7 92.9 75.6 81.1 84.5 15.8 19.2 23.7 10.1 26.7 42.1 35.2 40.2 33.0 32.0 24.6 19.4 17.6 20.0 28.6 27.6 10.4 94.7 16.2 20.4 27.4 48.5 21.6 21.4 19.7 27.3 39.0 45.2 19.8 51.6 90.2 24.9 23.4 28.4 22.8 25.4 20.0 46.1 46.3 62.2 22.2 40.0 32.6 23.0 21.6 3.6 37.0 19.3 26.6 11.2 41.2 25.4 21.6 10.1 11.8 33.4 27.7 38.7 31.9 40.4 27.8 27.9 17.8 25.3 46.0 22.4 22.6 25.2 38.0 37.4 41.6 40.6 24.8 24.8 55.1 26.3 PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 26.3;Extravillous trophoblasts: 22.3;Granulosa cells: 14.4;Kupffer cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" 1.3 0.7 1.8 6.5 2.0 18.1 1.8 4.3 2.7 1.2 1.1 4.6 6.5 1.7 0.5 3.8 1.4 1.4 1.0 2.0 1.3 0.6 1.4 2.3 10.3 2.3 1.5 1.4 0.5 0.3 0.0 4.3 2.2 0.8 5.6 1.7 0.6 0.7 1.2 3.1 5.0 3.6 1.1 3.3 2.4 1.8 2.3 20.6 1.3 0.4 12.0 2.0 0.6 3.7 105.3 56.9 84.5 24.8 2.4 16.0 31.7 66.7 41.9 69.1 54.2 68.4 78.7 80.2 65.9 52.7 56.2 40.7 67.0 73.9 145.0 99.3 39.1 86.4 58.8 50.3 0.6 88.7 32.5 4.0 5.3 81.9 109.0 17.1 77.2 57.9 48.6 76.7 72.8 95.2 80.7 26.1 31.9 52.0 82.5 67.3 135.7 45.9 20.0 32.4 34.5 45.4 61.7 18.4 29.2 38.0 54.4 34.1 57.8 146.4 157.3 73.5 117.8 48.8 108.2 73.6 34.5 47.4 150.1 1.7 2.1 2.3 0.6 4.0 0.2 1.1 0.5 0.7 2.6 0.6 0.3 0.5 2.1 0.5 9.5 1.1 1.4 0.8 1.8 2.0 4.3 2.7 2.0 1.3 2.3 1.5 2.2 1.1 2.3 3.7 4.5 0.0 1.7 3.3 3.1 1.9 2.0 1.5 0.0 2.0 0.8 1.5 2.0 1.5 1.6 0.0 0.0 6.2 1.4 2.0 0.0 0.4 0.9 1.4 1.9 3.6 4.9 26.3 1.6 0.5 22.3 2.9 2.6 2.2 2.5 14.4 4.2 0.3 7.8 1.7 1.8 5.0 0.0 18.6 6.3 0.4 0.9 7.8 1.8 2.8 8.4 0.9 4.1 2.0 3.4 0.9 0.7 2.2 9.7 1.1 0.5 0.5 0.6 3.2 0.0 2.9 3.3 2.6 5.1 5.5 1.3 2.1 3.3 1.3 8.4 1.7 PRSS57 "PRSSL1, UNQ782" ENSG00000185198 "Serine protease 57" Q6UWY2 19 685546-695498 "Enzymes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "bone marrow: 165.3" "Cell type enriched" "Detected in some" 9 "Erythroid cells: 77.8" "Cancer enriched" "Detected in single" 10 "pancreatic cancer: 2.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 13 "NB-4: 377.2;THP-1: 184.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (2.89e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (3.99e-4)" "unprognostic (3.07e-1)" "unprognostic (1.33e-2)" "unprognostic (3.50e-2)" "unprognostic (4.04e-2)" "unprognostic (7.70e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (8.16e-2)" "unprognostic (2.56e-2)" 0.1 0.0 0.0 0.0 0.0 165.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.1 7.9 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 377.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.4 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.0 3.2 0.0 5.9 1.1 0.0 0.4 0.2 0.0 0.0 0.0 3.1 1.5 0.0 0.0 0.5 0.7 2.5 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 77.8 0.1 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.0 0.0 2.5 1.0 8.2 0.0 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840999-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "bone marrow: 2098.1" "Cell type enriched" "Detected in some" 17 "Erythroid cells: 26.5" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.0" "Cell line enriched" "Detected in some" 6 "THP-1: 2054.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced Approved Vesicles,Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Vesicles "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.8 0.2 0.6 0.0 0.7 2098.1 0.4 0.2 1.3 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 1.6 0.6 0.4 0.3 2.8 11.7 0.4 0.3 0.4 0.1 0.1 0.2 1.3 0.6 0.4 0.3 0.0 0.0 1.6 0.0 0.3 1.3 0.0 0.0 0.2 38.2 0.1 0.2 0.6 7.1 0.4 0.0 0.0 0.0 0.1 0.4 1.2 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 343.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 2054.4 0.0 0.0 0.0 0.2 0.9 0.0 0.2 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 9.9 0.6 0.7 0.2 1.3 0.6 0.4 0.3 0.4 0.4 0.2 0.6 0.4 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.8 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 26.5 0.4 0.0 0.9 0.9 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 1.5 0.0 0.1 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 PSMC3IP "GT198, Hop2, HUMGT198A, TBPIP" ENSG00000131470 "PSMC3 interacting protein" Q9P2W1 17 42572310-42577831 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 113.3;Spermatogonia: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA044439 Enhanced Supported Nucleoplasm NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA044439: AB_10964210" "unprognostic (2.98e-1)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (2.87e-1)" "unprognostic (6.59e-2)" "unprognostic (2.39e-2)" "unprognostic (1.28e-7)" "unprognostic (6.22e-2)" "unprognostic (6.14e-2)" "unprognostic (2.47e-1)" "unprognostic (7.26e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (9.41e-4)" "unprognostic (6.03e-2)" "unprognostic (3.68e-1)" "unprognostic (1.39e-2)" "unprognostic (1.82e-1)" 3.3 1.4 8.3 2.5 8.9 8.2 3.8 8.7 10.3 3.5 7.9 4.2 1.3 3.7 3.8 3.0 6.2 1.4 1.8 7.8 8.5 2.8 0.8 2.3 3.9 9.4 8.9 3.4 2.1 7.6 1.5 4.2 9.2 3.6 3.0 7.3 1.5 3.9 1.5 3.1 1.6 5.2 9.0 1.9 2.4 23.7 8.8 7.4 1.8 2.3 5.5 2.9 2.9 8.9 21.1 29.0 48.3 34.9 11.0 15.0 11.0 80.4 23.7 63.4 78.3 28.6 12.9 21.1 17.6 22.2 27.6 29.9 36.9 28.8 73.0 31.0 30.0 13.5 66.1 35.0 1.6 46.3 14.4 5.3 6.4 101.5 34.2 9.4 18.8 28.3 44.5 38.2 56.6 21.8 33.3 28.0 30.0 23.9 26.8 32.3 50.7 20.6 14.8 16.6 65.1 40.6 32.1 11.8 34.7 24.3 28.3 20.3 8.8 70.5 41.1 55.2 128.6 30.0 54.1 30.8 32.8 21.2 79.7 0.0 0.0 0.9 0.7 0.2 0.9 1.1 0.4 0.7 0.0 0.3 0.1 0.4 0.9 0.1 0.3 2.8 0.7 0.1 8.3 8.9 8.7 10.3 7.8 8.5 9.4 8.9 9.2 9.0 8.8 8.9 6.0 3.2 3.7 2.3 6.4 5.4 2.7 3.7 0.0 5.9 4.8 5.2 0.9 4.3 2.8 3.7 10.4 15.6 3.7 1.4 0.0 4.5 12.8 11.1 5.8 4.4 0.0 19.8 1.1 3.3 19.1 5.5 1.5 5.0 1.3 7.7 2.9 2.2 7.4 0.0 1.2 1.2 4.1 3.0 2.6 13.1 5.3 2.4 5.4 2.8 5.8 4.6 3.1 1.0 1.5 2.0 0.3 8.6 6.5 2.0 0.2 2.2 14.9 13.9 19.7 8.6 16.0 113.3 44.6 3.2 4.1 5.2 2.7 2.5 2.5 1.7 PTTG1 "EAP1, HPTTG, PTTG, securin, TUTR1" ENSG00000164611 "PTTG1 regulator of sister chromatid separation, securin" O95997 5 160421855-160428739 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.1;lymphoid tissue: 144.9;testis: 175.6" "Cell type enhanced" "Detected in many" "Early spermatids: 770.5;Erythroid cells: 415.9;Langerhans cells: 412.3;Spermatocytes: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 218.0" "Lineage enriched" "Detected in all" 7 "T-cells: 218.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008373, HPA008890, HPA045034" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "CAB008373: AB_592493, HPA008890: AB_1079717, HPA045034: AB_2679192" "unprognostic (6.48e-2)" "unprognostic (1.03e-2)" "unprognostic (1.40e-3)" "unprognostic (4.46e-3)" "unprognostic (5.81e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (7.50e-3)" "unprognostic (5.24e-2)" "unprognostic (3.47e-2)" "unprognostic (2.13e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.23e-2)" "unprognostic (3.35e-2)" 3.7 3.5 4.2 25.2 5.3 160.1 10.9 4.1 11.5 9.6 4.0 33.9 24.6 4.8 9.6 59.7 5.0 6.1 3.5 8.1 6.6 3.0 5.3 8.7 81.5 3.9 4.8 1.8 1.5 2.3 4.3 21.2 4.2 3.1 44.1 2.4 10.3 2.7 2.5 36.0 24.1 19.2 4.0 18.6 11.8 175.6 5.3 127.0 79.3 1.3 144.9 12.5 19.9 4.7 345.4 178.2 385.8 279.5 64.4 63.3 120.8 177.5 406.1 463.4 503.5 341.1 294.9 373.3 154.7 204.2 527.5 176.1 243.5 496.1 661.2 428.3 220.3 196.7 241.8 208.6 13.0 181.5 165.6 29.6 81.5 315.4 189.5 139.9 333.4 243.3 160.7 282.3 485.4 162.3 220.7 446.1 197.5 279.3 251.4 199.4 452.4 320.7 239.6 82.6 241.0 151.3 258.6 156.3 535.6 309.3 319.9 195.7 144.8 208.3 275.9 164.9 531.3 239.2 235.6 432.3 225.9 310.4 379.6 9.7 3.2 10.3 25.5 8.7 9.6 30.9 52.3 60.6 23.9 23.5 12.7 31.4 3.0 14.6 5.8 22.6 218.0 19.8 4.2 5.3 4.1 11.5 8.1 6.6 3.9 4.8 4.2 4.0 5.3 4.7 11.8 6.4 21.5 0.0 40.0 247.9 64.5 163.6 142.3 3.4 15.8 40.5 4.0 4.3 31.1 5.5 0.0 125.4 38.3 17.7 3.9 5.8 770.5 22.7 9.3 20.6 6.0 415.9 1.3 5.3 196.2 35.6 28.1 16.7 37.5 66.2 18.5 7.1 87.5 0.0 1.6 39.2 126.1 36.3 412.3 105.1 11.1 39.1 87.2 0.0 24.7 3.5 6.2 0.0 0.6 3.0 10.7 7.9 91.4 54.1 9.0 2.0 17.1 1.0 6.6 18.6 43.2 708.0 57.3 232.0 156.1 31.9 73.7 16.8 70.3 50.3 RACGAP1 MgcRacGAP ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9;lymphoid tissue: 43.0;testis: 45.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 55.7;Extravillous trophoblasts: 49.4;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB025859: , HPA039427: AB_2676503, HPA043912: AB_2678728" "prognostic unfavorable (1.51e-4)" "unprognostic (1.91e-1)" "unprognostic (3.74e-3)" "unprognostic (1.53e-2)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.15e-3)" "unprognostic (3.07e-3)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.12e-6)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (3.13e-2)" "unprognostic (4.94e-1)" "unprognostic (6.16e-2)" "unprognostic (2.15e-1)" 5.0 2.5 5.5 13.7 8.2 38.9 7.1 6.9 6.3 5.2 3.2 16.7 10.5 5.3 1.5 21.3 4.4 6.4 2.8 5.0 6.0 9.2 4.7 6.2 23.9 6.7 7.1 2.4 2.7 5.8 1.4 14.0 6.5 3.3 18.7 5.3 4.8 3.4 4.9 14.4 11.6 12.5 5.5 6.5 9.8 45.5 7.6 43.0 3.3 4.8 30.2 7.7 8.0 7.0 193.0 174.5 135.8 86.8 24.8 29.7 113.0 195.0 97.0 207.3 140.3 174.6 144.7 107.5 86.0 108.3 99.9 127.1 137.7 93.6 219.9 203.0 85.4 137.9 165.8 58.1 8.4 146.1 109.0 16.2 17.2 140.7 111.4 60.3 71.7 96.4 101.6 159.6 197.0 136.8 122.5 72.6 96.2 108.9 112.9 113.9 163.5 78.3 54.9 95.7 113.9 97.5 161.7 102.7 53.0 68.8 199.7 64.8 64.9 136.2 119.1 86.8 144.7 83.3 225.2 126.6 67.7 97.0 81.1 24.1 3.2 4.7 6.5 4.1 5.7 8.2 7.9 9.2 2.8 4.3 4.6 6.1 0.7 11.0 2.6 1.8 19.1 5.8 5.5 8.2 6.9 6.3 5.0 6.0 6.7 7.1 6.5 5.5 7.6 7.0 2.0 6.4 6.4 2.9 4.2 12.9 2.5 4.9 6.2 1.5 4.8 5.1 1.5 2.8 3.3 5.5 4.2 21.8 4.4 3.1 19.6 1.9 15.2 2.2 3.1 2.7 0.0 55.7 7.5 2.2 49.4 5.9 7.7 4.0 2.5 14.2 5.3 2.7 13.1 1.7 8.0 5.7 20.3 11.3 8.0 17.7 1.5 7.1 1.8 1.0 4.5 2.7 6.2 6.0 12.3 2.0 1.0 3.8 10.9 2.8 1.1 2.1 2.3 0.8 13.1 3.1 5.5 79.6 32.2 19.5 12.9 8.6 6.9 2.2 11.6 2.9 RAD18 RNF73 ENSG00000070950 "RAD18 E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752" Supported Approved Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "HPA006716: AB_2667650, HPA006724: AB_2667655, HPA008752: AB_2668129" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.01e-1)" "unprognostic (9.76e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.73e-4)" "prognostic unfavorable (3.65e-5)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (7.92e-2)" "unprognostic (1.89e-2)" 2.7 2.3 1.2 3.3 1.5 5.2 5.3 1.3 1.7 3.2 0.5 3.8 10.1 2.8 1.9 3.4 2.3 3.1 1.8 1.5 0.9 1.6 2.7 2.7 4.6 1.6 1.0 2.8 1.7 2.0 1.3 3.0 1.5 3.2 4.9 2.6 3.2 1.6 1.3 4.5 6.5 2.8 1.2 3.5 2.2 2.9 1.1 5.8 3.7 1.0 4.4 2.5 2.9 2.3 16.2 15.2 12.3 7.4 3.0 6.4 14.9 25.0 8.5 23.5 16.1 13.7 10.1 19.8 4.7 14.2 13.8 5.6 13.1 13.0 23.8 12.2 17.2 16.9 16.1 8.2 1.9 22.7 13.9 2.4 4.6 23.3 15.7 6.3 7.7 17.1 18.2 19.0 20.9 18.6 22.9 15.9 17.2 12.7 28.5 18.0 13.6 15.6 6.9 12.2 5.1 11.5 11.2 10.5 8.2 9.7 11.0 9.8 6.4 19.4 10.5 16.8 21.7 9.6 16.1 43.7 14.3 24.5 14.6 6.4 1.6 5.1 1.5 1.7 2.8 1.9 2.1 2.7 2.0 1.9 2.2 1.6 0.7 2.8 1.1 3.6 3.0 0.8 1.2 1.5 1.3 1.7 1.5 0.9 1.6 1.0 1.5 1.2 1.1 2.3 5.7 16.0 9.8 6.2 7.7 11.1 7.5 6.4 5.7 4.6 7.3 11.7 2.2 4.3 7.5 3.7 2.1 9.0 8.6 5.2 1.9 9.6 4.2 4.0 5.8 4.6 1.8 7.2 20.9 8.2 12.4 6.8 3.6 4.9 13.9 14.8 6.1 3.1 7.1 3.3 15.7 6.5 2.0 5.2 5.6 3.0 4.1 4.6 3.6 14.0 7.1 3.2 8.2 16.1 14.3 10.2 4.3 2.6 8.7 6.4 4.0 3.1 4.1 2.3 6.6 4.3 6.9 26.2 14.0 6.0 11.8 6.7 7.5 9.3 6.3 3.6 RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.7;testis: 24.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Extravillous trophoblasts: 67.2;Spermatocytes: 53.6;Spermatogonia: 24.8;Syncytiotrophoblasts: 25.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010381, HPA039310" Enhanced Supported "Nucleoli rim,Cytosol" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoli rim" Cytosol "CAB010381: AB_2253533, HPA039310: AB_2676434" "prognostic unfavorable (7.94e-4)" "unprognostic (7.20e-3)" "unprognostic (1.22e-1)" "unprognostic (2.72e-2)" "unprognostic (8.23e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (2.53e-3)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (9.59e-2)" "unprognostic (1.94e-2)" 0.9 0.6 0.4 5.5 0.5 10.5 1.9 1.7 0.7 1.0 0.6 8.3 3.2 1.2 0.4 4.2 0.7 1.3 0.6 0.4 0.5 0.5 1.3 1.1 11.0 0.4 0.3 0.6 1.4 0.5 0.2 6.8 0.5 0.8 9.1 0.3 1.0 0.3 1.0 3.1 4.1 2.4 0.1 2.4 1.8 24.3 0.3 15.7 0.6 0.5 13.3 1.7 1.5 0.5 33.8 16.1 33.4 16.3 4.4 7.8 31.1 54.9 16.5 43.3 43.8 35.4 22.1 20.4 26.8 20.9 18.9 67.7 56.6 22.1 42.3 39.0 22.2 47.7 28.2 30.4 0.4 37.9 28.5 1.7 2.9 30.0 13.5 6.4 22.5 48.5 59.6 55.8 36.6 28.5 54.4 43.6 35.2 69.2 19.0 61.0 49.0 30.7 15.4 45.3 15.4 27.0 23.6 41.4 8.5 39.2 27.0 39.4 9.9 32.8 22.2 48.7 27.2 12.0 65.1 59.8 16.3 78.0 33.5 1.3 0.6 1.7 2.4 1.3 0.6 1.7 2.5 3.2 1.0 1.1 0.6 1.2 1.2 1.8 1.4 0.9 5.9 1.2 0.4 0.5 1.7 0.7 0.4 0.5 0.4 0.3 0.5 0.1 0.3 0.5 0.0 0.0 0.0 0.3 1.9 3.6 1.5 2.0 0.0 0.8 0.1 0.0 0.9 0.0 1.0 0.0 0.0 35.3 1.4 3.0 0.0 0.0 5.7 0.2 0.2 1.0 0.0 16.0 1.6 0.0 67.2 1.3 2.0 0.2 0.0 0.6 2.2 0.2 12.7 0.0 1.2 5.3 2.0 1.6 1.7 5.3 0.6 0.5 0.0 1.0 0.3 0.3 2.1 0.5 0.6 0.1 5.0 0.7 8.2 0.9 1.0 0.0 0.1 0.0 0.0 0.5 0.9 53.6 24.8 3.9 1.6 25.3 1.2 0.1 8.0 2.1 RAD51AP1 PIR51 ENSG00000111247 "RAD51 associated protein 1" Q96B01 12 4538798-4560047 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Meiosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.9;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in many" "Early spermatids: 33.4;Erythroid cells: 47.8;Extravillous trophoblasts: 34.1;Hofbauer cells: 40.8;Late spermatids: 68.1;Spermatocytes: 35.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051499 Approved Nucleoplasm Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051499: AB_2681508" "unprognostic (1.03e-1)" "unprognostic (5.44e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (6.30e-2)" "unprognostic (5.25e-3)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.15e-2)" "unprognostic (2.26e-2)" "unprognostic (6.29e-3)" "prognostic unfavorable (1.22e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.44e-15)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.88e-2)" "unprognostic (3.75e-2)" 0.9 0.8 0.3 4.8 0.4 16.9 2.7 0.4 0.7 0.9 0.3 5.2 5.2 1.2 0.6 3.2 1.0 1.1 0.5 0.3 0.3 0.8 1.8 1.4 8.9 0.4 0.4 0.5 0.4 0.6 0.3 3.8 0.4 1.3 6.5 1.5 1.0 1.0 0.5 3.2 4.8 1.9 0.4 3.4 2.7 6.3 0.4 14.4 1.0 0.6 7.9 1.7 1.3 0.5 37.5 13.0 45.3 22.7 2.7 5.7 53.0 48.2 21.2 52.6 68.9 35.4 35.4 48.6 7.0 10.4 24.7 23.1 31.8 14.5 80.0 38.7 27.0 61.4 21.6 24.8 0.6 56.6 29.9 1.2 1.5 31.6 30.4 7.5 21.4 33.0 39.2 54.4 33.7 13.6 46.5 20.5 110.4 36.3 14.4 46.0 54.3 19.2 16.1 18.3 15.1 16.6 35.9 27.7 11.6 45.5 11.3 32.6 9.5 35.5 36.5 38.8 52.4 7.8 10.0 93.3 13.3 40.0 29.4 0.0 0.5 0.7 0.1 2.3 0.5 3.1 0.4 1.0 0.4 3.4 0.1 0.2 0.0 1.4 2.0 6.9 1.0 0.6 0.3 0.4 0.4 0.7 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.5 1.4 0.0 0.5 0.7 6.1 5.2 2.3 6.6 1.2 3.1 3.4 5.7 1.4 2.8 4.5 0.0 4.2 20.3 11.3 5.7 0.0 3.0 33.4 3.3 2.9 2.9 2.4 47.8 2.7 2.7 34.1 5.2 6.1 3.6 1.3 22.6 2.5 1.2 40.8 0.0 1.1 6.4 16.2 6.2 5.6 68.1 1.2 10.1 0.0 3.7 6.8 2.7 3.1 0.5 2.4 1.5 0.8 1.5 15.5 1.0 1.2 1.5 0.9 4.8 0.0 2.4 4.2 35.9 25.0 10.0 2.6 4.7 4.6 2.0 14.6 2.7 RAD51C "FANCO, RAD51L2" ENSG00000108384 "RAD51 paralog C" O43502 17 58692573-58735611 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.7;Spermatocytes: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 319.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045198 Supported "Nucleoplasm,Vesicles,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Mitochondria, Cytosol" "Vesicles, Cell Junctions" "HPA045198: AB_2679250" "unprognostic (5.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (6.20e-2)" "unprognostic (1.83e-1)" "unprognostic (4.59e-2)" "prognostic unfavorable (8.68e-5)" "unprognostic (3.65e-2)" "unprognostic (2.91e-2)" "unprognostic (1.03e-2)" "prognostic favorable (5.33e-4)" "unprognostic (2.55e-1)" "unprognostic (2.62e-2)" "unprognostic (7.62e-2)" "unprognostic (2.41e-1)" "unprognostic (9.52e-2)" "unprognostic (2.42e-2)" 10.8 20.2 15.5 10.0 15.7 23.1 15.3 19.0 18.4 10.8 13.4 12.4 7.5 12.6 22.0 13.0 11.2 11.0 25.7 16.4 15.0 12.8 13.3 8.8 22.0 14.9 13.8 12.5 10.6 20.1 10.5 15.1 16.0 17.4 14.5 13.5 10.7 12.0 18.3 10.6 8.7 13.8 13.2 12.2 11.6 20.2 14.6 21.2 12.3 17.3 19.1 10.9 8.6 18.2 63.7 72.1 43.3 48.5 22.9 19.6 100.1 34.2 14.5 43.5 55.3 31.0 39.3 37.4 48.9 23.5 58.8 23.3 59.5 46.6 81.7 91.6 123.0 53.0 84.6 119.4 23.3 69.1 45.0 12.1 42.2 47.8 38.6 24.0 50.0 60.9 83.6 48.5 37.0 319.1 96.8 95.3 12.1 42.5 66.5 62.1 69.5 69.8 26.9 39.6 54.3 49.6 27.3 12.0 53.5 11.1 39.2 71.6 16.5 37.6 100.1 34.3 42.4 44.1 187.2 111.5 38.3 67.1 42.0 27.6 9.2 12.5 15.6 14.3 15.2 18.0 16.9 17.2 15.9 17.3 18.2 17.4 5.1 15.0 12.5 14.3 27.1 11.0 15.5 15.7 19.0 18.4 16.4 15.0 14.9 13.8 16.0 13.2 14.6 18.2 20.5 19.2 13.9 10.1 20.5 11.9 18.7 42.9 15.9 15.0 25.1 34.0 63.7 7.2 20.9 16.5 6.2 67.8 15.0 7.1 58.7 25.7 117.7 17.3 13.0 19.3 6.7 43.8 21.5 18.6 94.1 19.8 7.1 13.0 22.9 23.3 15.7 15.7 33.4 16.8 17.7 11.7 32.6 16.1 47.7 65.4 17.4 21.8 24.9 13.1 18.7 31.3 21.6 23.1 22.8 13.0 10.4 15.4 28.5 17.2 5.7 24.6 14.1 26.9 32.9 14.7 23.9 140.7 98.3 15.9 10.7 36.3 20.5 28.2 15.3 13.9 RAD54L "hHR54, hRAD54, RAD54A" ENSG00000085999 "RAD54 like" Q92698 1 46246461-46278480 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.4;testis: 15.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 7.2;Extravillous trophoblasts: 9.4;Glandular and luminal cells: 8.0;Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028954, HPA051537" Approved Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028954: AB_2672840, HPA051537: AB_2681525" "unprognostic (2.12e-2)" "prognostic favorable (6.67e-4)" "unprognostic (5.12e-2)" "unprognostic (5.36e-3)" "unprognostic (3.24e-1)" "unprognostic (1.08e-2)" "unprognostic (9.75e-6)" "unprognostic (3.91e-2)" "unprognostic (2.17e-3)" "unprognostic (2.95e-2)" "unprognostic (1.77e-4)" "unprognostic (5.58e-2)" "unprognostic (1.11e-16)" "unprognostic (6.76e-3)" "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" 0.5 0.7 3.0 4.1 3.8 8.7 1.0 4.3 3.9 1.3 2.1 3.2 2.0 0.7 0.1 5.4 0.4 0.5 0.7 2.9 2.5 1.4 0.5 1.2 5.5 3.2 3.0 0.5 0.5 0.3 0.4 3.4 3.8 1.0 4.6 0.4 0.9 0.4 1.2 2.3 2.8 1.7 2.8 2.8 1.5 15.6 3.1 15.4 1.8 0.0 8.3 0.8 1.8 3.7 22.2 16.1 46.8 29.1 3.3 2.4 43.9 25.8 11.3 42.8 43.3 33.3 14.2 42.5 19.1 11.0 38.5 22.2 44.6 14.5 36.8 23.7 43.0 53.0 49.7 32.1 0.1 54.0 29.3 1.6 1.2 42.1 12.5 6.9 13.5 49.7 38.2 41.7 23.1 20.4 68.9 60.0 42.5 19.4 25.2 52.8 26.8 19.0 9.4 17.5 22.4 16.3 18.4 25.2 5.7 38.0 9.1 37.7 5.7 43.9 26.1 23.6 43.7 17.6 10.6 46.9 11.5 35.1 18.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.2 3.0 3.8 4.3 3.9 2.9 2.5 3.2 3.0 3.8 2.8 3.1 3.7 0.0 0.0 0.0 1.0 0.7 0.3 0.7 0.5 1.8 0.0 0.5 0.5 0.8 0.0 0.1 0.0 0.0 4.3 0.4 1.8 0.0 0.3 2.7 2.3 0.8 0.5 0.0 7.2 2.8 0.0 9.4 1.1 0.5 8.0 4.5 5.6 0.4 0.0 2.6 0.0 1.1 1.3 0.0 0.3 0.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 1.0 1.0 2.9 0.3 0.1 0.0 4.7 0.4 0.4 0.0 0.1 0.0 0.0 0.4 4.0 12.4 5.6 3.1 0.3 1.6 1.1 0.2 2.9 1.0 RCCD1 MGC14386 ENSG00000166965 "RCC1 domain containing 1" A6NED2 15 90954870-90963125 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039683, HPA040776" Enhanced Enhanced "Plasma membrane,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA039683: AB_10794752, HPA040776: AB_10795478" "unprognostic (1.01e-2)" "unprognostic (1.69e-2)" "unprognostic (7.22e-3)" "unprognostic (8.63e-2)" "unprognostic (6.18e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (5.86e-2)" "unprognostic (4.83e-2)" "unprognostic (5.10e-2)" "unprognostic (5.69e-2)" "unprognostic (2.72e-2)" "unprognostic (1.49e-3)" "unprognostic (1.32e-2)" "unprognostic (2.41e-1)" "unprognostic (4.71e-2)" "unprognostic (3.94e-2)" 3.9 8.8 4.1 3.0 4.3 4.6 3.5 5.5 5.2 6.9 5.0 6.3 5.1 5.5 3.5 6.6 6.0 2.0 5.9 4.0 3.6 6.2 6.7 2.6 3.9 3.3 3.2 7.3 9.2 5.2 2.9 2.2 3.7 5.4 4.5 3.1 5.0 2.8 3.8 7.4 4.8 2.8 2.9 4.3 6.7 5.8 3.5 4.7 4.5 1.0 4.7 5.5 5.7 3.4 8.0 11.7 2.7 5.7 6.6 7.8 20.2 9.1 1.6 2.6 2.7 5.6 14.9 28.0 14.2 5.6 0.2 16.8 8.9 2.4 4.3 23.7 18.2 20.3 21.2 8.0 5.5 9.8 7.7 5.8 8.0 2.6 3.6 10.3 4.3 16.2 15.7 18.0 7.8 2.7 11.8 10.2 10.4 9.6 4.8 14.0 13.6 30.4 12.0 3.6 8.8 10.1 15.8 10.0 11.6 14.2 11.5 18.7 6.9 1.6 11.2 6.6 0.4 31.9 14.1 16.9 3.0 21.4 7.7 0.0 0.2 0.0 0.2 0.6 0.5 0.8 0.4 0.7 0.4 0.5 0.8 0.2 0.0 0.5 0.3 0.6 0.6 0.2 4.1 4.3 5.5 5.2 4.0 3.6 3.3 3.2 3.7 2.9 3.5 3.4 6.0 0.0 2.2 7.5 9.7 7.4 11.3 9.0 7.4 6.2 9.9 10.9 8.5 4.3 5.3 7.3 4.2 20.9 5.0 14.9 3.9 8.0 3.1 3.2 8.2 5.0 22.1 56.8 9.6 4.9 18.4 8.0 8.2 5.7 0.0 12.5 4.2 8.5 12.0 0.0 11.3 20.5 6.1 8.1 4.0 6.5 8.7 5.7 5.4 3.7 4.3 11.1 10.3 8.5 2.0 5.0 11.7 7.9 9.4 9.8 17.4 13.7 2.9 2.9 26.3 9.7 9.2 22.2 20.1 17.2 8.9 9.0 4.6 10.2 25.7 7.3 RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" O94761 8 144511288-144517845 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;testis: 22.4" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.5;Spermatogonia: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB017800: , HPA025821: AB_1856168" "unprognostic (5.92e-2)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (9.17e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.12e-2)" "unprognostic (4.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" 1.7 1.8 3.0 5.8 3.7 25.4 2.0 7.7 7.0 2.9 0.1 4.7 6.0 2.5 0.4 13.3 2.1 2.1 1.8 2.6 1.6 2.5 2.7 2.3 6.8 6.9 2.3 2.7 3.1 0.7 3.1 2.5 7.4 8.6 1.6 1.5 5.8 0.8 2.5 10.1 5.2 1.0 1.7 6.5 3.2 22.4 4.1 7.4 3.4 0.5 2.5 2.5 3.1 3.6 33.7 58.8 27.0 57.1 1.6 2.6 47.1 33.2 5.9 24.2 20.2 58.4 48.4 22.8 21.5 5.6 14.2 40.1 18.0 14.2 6.6 40.3 68.6 82.4 118.5 44.3 0.5 21.2 65.7 3.3 2.1 27.1 5.5 3.4 6.8 45.4 83.3 28.9 8.5 104.1 77.3 56.9 18.8 27.8 69.5 80.0 21.2 37.9 6.7 35.8 52.9 32.0 45.2 37.3 12.1 7.4 45.5 45.7 9.2 38.9 117.4 47.3 62.6 16.0 18.1 39.3 22.4 64.6 39.9 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.7 7.7 7.0 2.6 1.6 6.9 2.3 7.4 1.7 4.1 3.6 0.7 0.0 0.0 2.0 2.2 1.5 0.7 0.9 1.2 2.7 3.7 2.7 1.8 1.5 0.5 0.0 4.2 3.9 1.0 5.9 0.0 0.5 3.9 2.1 0.9 0.7 0.0 6.1 2.0 0.4 8.1 1.8 4.6 2.0 0.0 8.8 0.0 0.7 3.6 0.0 1.6 4.1 0.0 0.6 1.1 7.4 1.2 1.0 0.0 0.0 0.3 0.3 1.0 0.0 0.8 0.3 0.2 1.5 9.1 0.7 0.7 0.5 0.7 1.7 0.0 1.4 1.2 23.5 20.6 6.6 1.0 1.5 1.2 0.5 7.0 0.7 REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 89.3;skin 1: 91.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" 13.0 8.4 7.0 12.5 8.7 28.4 11.6 8.7 9.7 27.9 7.6 23.8 11.0 9.4 2.1 89.3 11.1 5.6 8.0 6.8 8.2 9.2 12.3 18.0 11.2 10.8 8.5 7.4 12.9 5.0 10.9 14.6 10.5 13.6 10.8 2.1 21.8 6.5 4.1 91.0 16.9 5.9 9.0 33.2 18.0 42.7 9.5 9.9 14.8 2.6 10.2 19.6 49.0 11.5 42.2 79.7 24.9 39.7 10.5 10.6 47.9 36.7 19.2 44.6 40.2 46.7 38.8 53.0 46.8 18.4 38.5 100.3 29.6 59.3 21.9 28.2 37.4 57.4 41.2 46.9 11.8 25.8 77.9 9.8 110.3 33.3 27.5 13.9 27.1 58.1 44.5 158.7 22.6 60.6 63.7 88.9 37.4 58.0 53.3 37.0 22.5 101.8 19.9 40.0 21.7 40.1 30.0 31.7 52.7 16.5 64.3 35.9 30.5 29.2 50.1 66.6 50.3 40.0 33.5 34.6 32.6 54.7 59.1 49.8 54.8 64.1 24.3 53.6 19.6 10.5 21.1 21.1 42.7 4.9 9.7 13.1 15.5 26.3 37.0 16.9 15.4 27.6 7.0 8.7 8.7 9.7 6.8 8.2 10.8 8.5 10.5 9.0 9.5 11.5 6.8 3.2 9.2 4.9 7.9 28.0 15.1 45.5 15.4 6.5 5.8 5.7 1.8 7.2 21.9 12.9 2.1 54.0 13.8 27.3 0.0 21.9 16.0 3.8 4.9 9.2 17.4 48.2 0.7 15.0 50.4 8.1 21.9 5.9 10.2 14.0 15.4 6.6 55.4 0.0 0.6 33.0 22.4 38.8 21.5 9.4 9.0 26.1 3.6 10.3 16.5 1.8 10.3 1.0 2.6 25.6 34.7 8.2 19.3 19.0 19.2 1.9 8.1 1.5 13.1 2.3 9.7 61.0 17.9 41.1 39.2 94.1 13.5 8.9 31.1 24.5 RFC2 "A1, RFC40" ENSG00000049541 "Replication factor C subunit 2" P35250 7 74231499-74254458 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029493 Approved Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "HPA029493: AB_10603991" "unprognostic (1.25e-1)" "prognostic favorable (9.91e-4)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (2.08e-2)" "unprognostic (5.74e-2)" "unprognostic (2.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.09e-7)" "unprognostic (2.22e-1)" "unprognostic (6.65e-2)" "unprognostic (3.61e-2)" "unprognostic (2.59e-1)" 12.2 9.5 10.6 13.4 10.9 27.4 15.5 11.4 11.5 12.6 11.1 13.4 9.0 9.6 8.4 18.6 10.1 8.6 10.1 10.5 10.9 14.7 21.2 11.3 23.5 11.7 11.3 11.3 13.3 11.8 7.9 18.4 11.4 11.5 15.0 8.8 12.2 7.6 18.8 20.3 11.2 12.6 11.5 14.2 13.6 10.0 10.7 20.2 9.2 12.2 30.8 11.5 12.6 11.8 74.3 55.6 65.2 64.6 13.1 15.2 29.4 42.5 46.7 85.2 101.4 62.6 67.3 69.2 11.5 30.7 78.7 49.7 53.3 69.2 87.5 49.6 91.5 42.9 76.4 46.7 10.1 64.6 25.3 15.4 15.9 79.8 55.0 18.5 46.0 63.9 89.4 41.9 66.4 87.2 65.1 124.7 74.1 116.3 47.4 95.0 72.0 85.8 45.7 58.1 52.4 65.5 50.7 94.8 34.7 79.2 68.7 58.0 17.4 83.4 54.9 64.6 96.3 25.1 35.1 120.6 42.4 98.4 89.3 33.4 36.7 27.3 18.0 42.3 18.1 31.6 15.5 16.5 31.9 36.8 19.5 14.3 46.4 42.9 40.1 17.1 23.9 29.1 10.6 10.9 11.4 11.5 10.5 10.9 11.7 11.3 11.4 11.5 10.7 11.8 15.4 12.8 11.1 2.6 19.0 23.8 24.3 24.3 19.9 13.2 12.6 17.4 6.1 5.7 16.5 5.5 2.1 68.6 17.5 12.4 5.9 21.0 2.8 8.1 13.3 13.5 4.8 38.3 3.0 19.0 65.0 17.4 10.7 11.5 23.4 25.1 13.6 14.0 37.7 3.3 2.6 13.1 20.3 14.4 28.2 2.5 8.7 18.2 21.4 1.9 26.3 16.1 23.7 1.5 2.2 13.8 6.9 10.9 17.5 11.0 13.2 13.8 8.8 9.5 6.6 14.6 17.5 33.8 44.6 20.1 17.0 46.1 16.9 12.9 19.1 15.3 RFC4 "A1, RFC37" ENSG00000163918 "Replication factor C subunit 4" P35249 3 186789880-186807058 "Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 55.7;Spermatocytes: 86.7;Spermatogonia: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004557, HPA049123, HPA058507" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004557: AB_2178593, HPA049123: AB_2680642, HPA058507: AB_2683736" "unprognostic (2.45e-1)" "prognostic favorable (7.41e-5)" "unprognostic (2.84e-1)" "unprognostic (1.81e-3)" "unprognostic (1.03e-1)" "unprognostic (6.69e-3)" "prognostic unfavorable (6.75e-7)" "unprognostic (5.29e-3)" "unprognostic (1.15e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (7.38e-4)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.80e-2)" "unprognostic (4.98e-1)" "unprognostic (6.15e-2)" "unprognostic (2.16e-1)" 7.0 6.0 7.3 19.3 7.6 41.5 13.8 8.9 11.9 8.8 7.4 15.4 10.9 14.1 6.6 11.8 10.8 7.7 9.1 7.5 7.5 7.3 10.7 7.2 31.5 7.3 7.4 15.0 11.0 8.0 5.7 14.5 7.6 7.7 20.4 11.2 8.6 7.0 8.3 11.7 11.7 17.6 7.5 14.3 10.4 22.7 8.1 35.7 7.3 6.7 34.5 7.8 8.2 8.3 167.3 56.2 130.8 83.6 18.8 20.1 103.0 78.9 49.9 123.6 135.8 84.8 77.9 119.5 177.4 38.0 118.0 86.1 116.5 77.5 151.1 180.5 102.5 123.3 86.3 86.3 14.6 131.8 79.5 17.3 27.5 84.9 66.1 27.6 42.0 183.8 97.9 165.4 85.3 79.7 167.2 122.8 116.0 148.1 76.0 129.9 112.5 164.3 44.9 60.7 126.3 63.3 97.3 107.6 90.3 97.6 183.0 123.7 19.6 74.4 93.3 125.8 239.9 91.9 216.9 398.9 65.3 142.8 100.0 0.0 2.8 9.7 11.5 4.2 11.1 13.1 11.4 12.0 5.0 15.1 11.2 10.2 0.6 9.8 14.7 9.6 21.8 7.7 7.3 7.6 8.9 11.9 7.5 7.5 7.3 7.4 7.6 7.5 8.1 8.3 5.1 0.0 2.2 3.3 14.0 6.0 15.3 18.1 5.2 16.1 4.1 8.1 7.5 5.7 9.3 11.0 0.0 43.0 9.7 4.4 5.9 15.3 27.3 5.6 7.0 6.1 1.2 46.3 5.2 16.6 55.7 8.3 6.6 6.0 8.2 25.3 6.1 3.0 23.9 8.4 4.4 7.1 10.2 2.6 4.9 10.0 10.5 6.2 1.8 4.7 12.2 14.9 9.2 2.5 4.3 9.2 4.1 7.9 23.8 3.8 2.8 7.9 7.9 14.4 6.6 10.2 13.1 86.7 50.5 7.9 3.0 11.2 9.6 8.8 13.9 4.7 RFC5 RFC36 ENSG00000111445 "Replication factor C subunit 5" P40937 12 118013588-118033130 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041037 Supported Approved Nucleoplasm NA NA 6500 "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA041037: AB_10805834" "unprognostic (9.63e-2)" "prognostic favorable (8.05e-5)" "unprognostic (5.12e-3)" "unprognostic (2.25e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-2)" "unprognostic (1.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.35e-3)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.44e-1)" "unprognostic (2.15e-1)" "unprognostic (2.70e-1)" "unprognostic (5.06e-1)" 5.9 5.8 3.7 10.5 4.4 33.8 10.7 5.9 4.9 8.6 4.2 10.3 9.8 11.1 5.4 9.3 9.5 6.7 5.4 6.0 2.9 8.7 13.0 6.8 16.4 3.3 3.2 15.6 7.6 7.1 4.7 7.3 3.2 7.9 12.6 11.5 5.8 8.0 5.6 12.9 9.1 7.7 3.8 8.0 7.2 8.3 3.7 23.4 10.3 4.7 16.1 6.3 7.1 4.3 52.8 49.3 49.1 28.1 12.2 14.7 58.3 38.4 24.0 66.6 49.9 50.2 21.4 56.4 25.9 18.1 42.0 47.2 66.9 34.0 63.2 42.1 58.1 43.9 40.7 36.5 7.6 70.7 38.1 7.8 12.2 50.0 16.8 30.4 28.6 70.3 62.6 21.6 33.3 50.3 93.2 59.2 40.5 29.8 46.1 68.1 61.2 55.3 30.7 47.7 67.5 30.7 62.2 18.2 24.1 30.4 64.4 30.0 13.7 36.9 42.5 50.4 69.5 36.2 51.7 76.9 36.4 51.7 66.1 16.6 5.0 3.6 8.6 8.4 7.6 10.7 10.3 7.4 7.2 9.1 8.0 6.9 5.6 7.9 4.9 6.0 11.4 6.5 3.7 4.4 5.9 4.9 6.0 2.9 3.3 3.2 3.2 3.8 3.7 4.3 4.0 0.0 3.3 4.6 5.6 8.4 6.9 7.1 4.0 4.2 5.2 4.7 3.1 4.3 4.6 9.2 2.1 21.0 4.7 3.6 9.8 8.9 3.0 6.0 6.3 4.3 4.2 45.7 11.8 6.3 25.2 6.4 4.1 6.5 5.7 14.0 3.3 6.0 9.1 1.7 7.3 6.9 4.1 3.2 3.1 2.7 4.1 4.9 0.0 3.7 3.8 9.5 2.1 2.5 5.5 4.1 4.0 8.2 16.4 2.3 3.2 6.6 11.0 6.0 0.0 5.3 8.4 13.4 9.1 9.5 5.4 8.9 7.9 18.7 10.6 4.2 RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621399-74666877 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 47.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA048258: AB_2680332, HPA075649: AB_2686761" "unprognostic (4.79e-2)" "unprognostic (6.45e-3)" "unprognostic (6.35e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-3)" "unprognostic (5.04e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.03e-3)" "unprognostic (2.53e-3)" "unprognostic (1.73e-3)" "unprognostic (2.84e-1)" "unprognostic (4.31e-1)" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" 5.2 3.9 2.5 9.9 3.5 47.7 7.6 4.0 3.2 6.4 4.4 8.0 6.5 6.2 5.3 9.4 6.8 6.5 2.9 2.3 2.9 6.7 5.8 6.1 15.4 3.3 3.1 7.0 10.2 6.8 3.8 8.0 3.2 4.9 9.3 6.2 5.8 5.1 3.3 12.6 6.1 6.1 2.8 8.1 6.2 25.2 3.4 27.1 6.6 2.7 16.7 7.2 6.8 4.7 46.1 57.5 42.6 31.2 8.8 11.9 47.8 40.5 30.9 63.0 54.5 75.4 46.8 63.6 32.1 31.8 31.6 53.9 70.3 42.1 76.9 20.0 42.1 56.3 46.0 43.0 7.6 57.3 56.3 8.6 13.2 79.6 48.7 16.3 27.3 53.2 86.7 27.7 48.1 72.8 84.0 52.2 84.0 26.8 27.7 128.7 28.8 55.9 22.7 47.8 31.5 33.6 65.2 22.8 28.8 38.2 41.7 48.4 26.7 46.0 43.9 26.2 51.4 37.4 75.1 188.3 32.8 43.5 57.0 12.1 4.4 6.5 5.5 4.1 6.1 4.9 4.5 5.1 4.6 5.4 6.7 4.8 4.9 6.2 7.7 3.5 7.2 4.4 2.5 3.5 4.0 3.2 2.3 2.9 3.3 3.1 3.2 2.8 3.4 4.7 6.0 0.0 5.9 4.2 13.2 10.8 6.8 4.0 10.2 6.6 8.4 8.3 3.9 2.8 5.4 1.8 10.4 12.1 15.3 7.6 11.7 6.2 5.4 6.9 5.7 7.2 9.5 22.5 8.9 7.6 8.3 5.9 5.1 6.6 4.5 13.5 11.7 7.4 8.9 3.3 7.1 9.7 2.0 12.2 6.0 6.3 3.7 7.8 16.0 15.0 7.6 3.0 10.3 6.6 15.2 10.0 2.7 4.1 11.6 12.7 4.3 4.6 5.9 6.7 6.6 6.4 5.6 48.5 31.7 9.5 9.2 7.5 10.6 3.6 9.5 11.4 RHNO1 "C12orf32, HKMT1188, MGC13204, RHINO" ENSG00000171792 "RAD9-HUS1-RAD1 interacting nuclear orphan 1" Q9BSD3 12 2876258-2889524 "Predicted intracellular proteins" "Cell cycle, DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (3.90e-2)" "unprognostic (4.86e-2)" "unprognostic (6.48e-3)" "unprognostic (1.86e-1)" "unprognostic (5.15e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (7.15e-2)" "unprognostic (1.19e-2)" "unprognostic (1.12e-3)" "unprognostic (4.83e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.74e-13)" "unprognostic (1.97e-1)" "unprognostic (1.64e-1)" "unprognostic (2.54e-2)" "unprognostic (4.53e-2)" 5.5 8.8 12.5 13.1 10.9 17.1 12.1 11.3 13.5 13.1 12.2 14.1 11.0 11.5 22.7 17.5 12.2 10.7 7.2 12.5 13.5 9.1 5.2 9.2 19.6 9.7 10.0 15.6 8.7 13.6 12.0 11.6 12.4 13.4 14.5 13.0 12.1 12.7 6.5 14.1 10.1 11.5 8.3 12.8 10.6 11.3 12.2 25.7 16.6 3.9 20.9 12.4 10.6 16.7 42.3 54.2 64.5 32.9 14.8 18.6 67.7 40.7 43.3 51.0 50.1 66.3 91.4 34.5 22.8 42.4 64.2 32.4 43.0 50.9 62.4 138.6 28.2 45.0 25.3 39.6 20.0 50.8 33.4 18.4 32.4 50.3 104.8 36.7 52.5 71.8 41.1 81.2 61.3 60.9 92.8 28.5 149.7 52.8 32.4 61.6 77.7 26.8 41.2 52.3 21.6 32.0 56.1 35.6 30.0 117.7 69.3 47.2 37.1 55.1 83.6 62.6 85.3 18.5 37.9 90.6 25.3 41.8 51.7 23.7 23.3 34.9 23.8 22.0 31.2 27.7 36.4 31.9 26.5 41.9 36.8 24.7 4.8 26.5 23.9 15.8 54.7 25.9 12.5 10.9 11.3 13.5 12.5 13.5 9.7 10.0 12.4 8.3 12.2 16.7 3.8 0.0 5.9 3.3 14.0 7.8 10.0 27.7 6.2 6.8 11.9 13.3 7.6 7.2 10.4 11.0 8.4 40.1 6.5 7.2 23.5 13.9 6.5 8.1 7.0 8.7 10.3 33.2 6.6 8.4 34.0 8.2 7.1 9.0 14.0 17.4 12.5 3.9 31.7 10.1 6.4 16.3 14.2 15.5 8.0 14.6 12.2 10.2 3.6 2.8 32.3 20.4 10.3 3.0 6.5 6.9 9.6 8.6 11.4 18.1 13.2 15.4 6.4 9.8 0.0 3.1 7.5 67.1 46.0 18.8 7.1 21.8 17.3 8.4 17.3 12.5 RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806584-12813640 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.3;Extravillous trophoblasts: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042692 Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA042692: AB_10793981" "unprognostic (6.74e-2)" "prognostic favorable (1.18e-4)" "prognostic favorable (6.18e-4)" "unprognostic (2.24e-1)" "unprognostic (2.62e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (8.48e-2)" "unprognostic (9.33e-2)" "prognostic favorable (1.22e-4)" "unprognostic (3.80e-3)" "unprognostic (8.71e-2)" "prognostic unfavorable (6.29e-6)" "unprognostic (3.40e-3)" "unprognostic (4.35e-2)" "unprognostic (5.35e-2)" "unprognostic (8.60e-2)" 8.9 6.8 7.0 11.8 7.2 28.0 9.0 10.4 9.1 10.8 6.2 10.5 10.3 8.5 4.9 18.3 10.6 4.9 7.6 7.2 6.1 7.4 6.9 7.3 17.1 7.3 6.5 8.9 9.2 5.3 5.4 10.4 7.4 6.0 10.7 8.4 8.6 5.0 8.9 13.9 10.0 8.2 6.0 14.5 9.4 19.8 6.8 24.4 7.5 6.6 18.7 8.2 10.8 9.5 130.0 103.8 94.8 75.7 12.3 23.4 76.2 68.4 40.0 126.3 136.0 76.2 58.7 126.9 106.2 36.6 59.6 79.4 82.6 89.2 83.5 82.7 118.1 67.7 112.9 89.9 7.1 70.6 60.5 10.4 19.7 110.7 43.9 21.4 47.3 114.8 91.2 46.8 82.0 251.4 132.8 83.0 56.4 79.1 167.4 146.1 102.0 113.7 39.6 63.8 119.8 76.7 67.0 39.8 46.7 39.8 76.1 78.4 29.3 129.2 55.7 197.0 126.1 97.6 130.3 108.5 77.4 129.4 105.5 9.4 19.1 17.2 23.9 27.6 23.3 36.8 19.6 22.5 19.0 36.3 15.9 19.6 4.4 44.8 27.7 21.0 25.8 19.1 7.0 7.2 10.4 9.1 7.2 6.1 7.3 6.5 7.4 6.0 6.8 9.5 5.3 0.0 2.6 1.3 15.3 14.0 15.7 22.9 6.8 16.2 2.8 11.7 2.7 12.8 7.6 0.0 4.2 62.3 9.1 11.3 0.0 5.4 16.1 0.8 1.6 9.0 8.4 38.7 2.2 6.0 117.4 10.3 10.7 1.1 3.8 2.5 11.7 4.4 48.9 8.4 3.0 13.9 22.4 9.1 13.2 18.8 8.4 9.3 12.4 1.9 8.5 10.4 14.4 1.0 2.4 2.1 6.8 4.9 33.0 5.3 6.2 1.0 9.5 13.9 6.6 15.6 9.8 51.2 44.9 23.8 13.2 22.7 10.2 0.8 24.8 16.1 RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337309 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favorable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.73e-4)" 14.3 15.8 12.7 11.5 12.6 22.0 13.3 13.7 15.1 15.4 10.6 19.2 14.5 23.5 10.3 20.9 16.6 10.5 13.2 12.7 12.5 13.6 23.6 12.4 11.8 15.2 13.1 17.1 13.8 18.5 10.4 14.2 15.5 14.8 12.6 8.4 14.9 18.6 8.5 15.7 17.0 19.0 12.7 14.6 19.1 15.1 14.7 13.3 13.2 7.1 12.8 18.9 14.2 13.1 43.8 47.4 43.4 51.4 41.8 32.8 46.0 46.3 49.7 52.8 41.5 80.6 88.9 38.3 62.5 55.5 80.1 77.2 61.9 69.8 33.0 46.0 34.2 101.0 21.8 67.3 31.9 42.8 40.4 34.3 35.2 66.1 59.0 34.7 40.8 58.1 50.0 58.4 36.9 94.9 39.5 44.3 43.5 50.2 59.8 40.5 44.5 30.4 32.7 31.1 30.8 29.9 37.4 46.8 12.5 41.4 106.1 35.4 27.0 63.5 41.8 33.7 43.0 14.0 24.6 0.4 21.3 71.0 50.6 9.5 21.6 5.6 20.8 19.2 13.4 11.1 15.7 18.4 19.0 16.7 17.5 15.5 1.5 14.0 20.2 11.0 8.7 24.9 12.7 12.6 13.7 15.1 12.7 12.5 15.2 13.1 15.5 12.7 14.7 13.1 5.1 3.2 9.4 1.0 9.1 6.9 13.3 15.4 12.5 9.2 10.9 9.8 0.8 22.8 11.1 11.0 2.1 44.0 6.2 9.3 5.9 20.8 6.6 5.9 7.9 8.6 13.8 18.5 3.2 17.0 66.0 11.5 9.2 5.9 7.6 16.9 11.4 23.4 21.5 5.0 2.9 13.0 8.2 14.8 5.9 8.6 14.0 6.6 1.8 1.0 11.6 11.6 15.5 4.5 2.7 14.1 7.5 17.7 4.3 14.2 15.6 12.5 4.8 9.4 6.6 6.5 10.6 19.9 10.5 14.3 8.5 24.4 8.3 8.8 18.6 9.8 RPP30 TSG15 ENSG00000148688 "Ribonuclease P/MRP subunit p30" P78346 10 90871952-90908553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037578 Approved Approved "Nucleoplasm,Nucleoli,Microtubule ends,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "Microtubule ends, Cytosol" "HPA037578: AB_10696939" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" "unprognostic (2.35e-1)" "unprognostic (4.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.05e-2)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.27e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.01e-6)" "unprognostic (1.98e-1)" "unprognostic (9.84e-3)" "unprognostic (3.43e-2)" "unprognostic (2.10e-2)" 19.2 13.9 7.8 12.9 8.8 25.9 17.3 8.2 10.6 14.1 7.3 15.3 9.3 15.8 14.1 18.0 14.9 12.7 22.6 8.8 8.4 16.3 15.1 13.1 21.0 7.1 7.3 18.1 11.0 23.0 8.0 18.5 7.6 12.1 15.1 13.2 14.5 12.2 31.1 17.9 12.4 16.4 8.3 15.0 14.3 28.6 7.7 21.7 12.2 22.2 22.4 17.0 14.2 10.6 82.2 53.2 55.0 66.5 34.4 37.6 19.4 57.0 51.1 93.3 98.3 90.6 64.1 48.1 42.6 36.4 60.9 56.0 73.9 50.5 95.3 77.2 51.3 32.7 31.1 73.0 33.0 66.7 39.1 30.9 32.4 70.5 79.1 39.6 54.1 43.5 65.7 42.6 62.6 50.8 77.4 89.8 33.9 46.4 59.8 42.9 46.7 50.4 35.6 38.2 29.9 29.9 33.1 23.8 68.2 50.0 64.8 41.3 31.2 46.3 46.3 26.5 119.6 28.7 79.4 104.4 57.9 35.4 36.4 9.2 30.0 27.1 25.2 30.7 27.5 31.7 28.7 28.0 35.1 28.1 24.6 27.0 3.5 25.4 26.2 32.8 33.0 27.6 7.8 8.8 8.2 10.6 8.8 8.4 7.1 7.3 7.6 8.3 7.7 10.6 31.4 32.1 16.9 14.0 28.7 34.4 27.5 51.8 23.9 19.2 16.7 28.2 45.7 27.1 31.4 14.7 18.8 60.6 33.7 9.4 31.3 41.9 95.9 18.9 26.1 25.2 19.8 38.5 18.0 35.0 68.1 28.0 13.3 17.9 23.5 33.3 21.4 14.3 58.1 16.8 19.4 21.0 30.5 23.9 29.3 49.9 28.9 24.7 23.2 11.2 32.2 23.3 15.5 17.6 19.6 31.3 12.5 29.3 20.6 18.8 12.5 36.5 21.6 24.3 39.5 30.1 36.9 77.9 54.2 20.2 34.0 33.8 23.7 28.6 17.6 27.6 RRM1 ENSG00000167325 "Ribonucleotide reductase catalytic subunit M1" P23921 11 4094707-4138932 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Allosteric enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022093, HPA057265, HPA064297" Enhanced Supported Cytosol NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB022093: , HPA057265: AB_2683386, HPA064297: AB_2685236" "unprognostic (4.47e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-3)" "unprognostic (3.65e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.31e-2)" "unprognostic (3.43e-2)" "unprognostic (6.90e-2)" "unprognostic (1.06e-3)" "unprognostic (4.21e-2)" "unprognostic (6.88e-3)" "unprognostic (9.20e-3)" "unprognostic (6.16e-2)" "unprognostic (8.41e-2)" "unprognostic (9.93e-3)" 16.6 21.2 5.1 24.8 5.3 32.8 22.7 7.1 6.1 16.9 4.7 25.7 19.3 16.2 10.1 26.5 15.5 11.8 16.4 5.1 5.7 13.4 18.4 12.8 34.4 6.1 5.5 16.4 14.6 24.7 7.1 20.4 6.6 18.5 29.4 23.6 14.7 16.0 30.3 36.1 20.2 20.1 6.2 13.0 17.6 17.9 5.1 56.7 15.6 30.0 45.2 15.6 18.9 6.2 221.6 117.8 188.4 110.0 28.4 56.2 73.0 198.0 98.2 220.7 225.9 106.8 163.8 237.4 47.0 100.1 95.9 173.0 176.9 143.2 259.3 117.3 187.9 121.0 159.8 83.1 11.2 208.9 84.6 26.6 37.8 121.7 86.4 48.3 107.8 140.1 161.1 107.3 186.8 99.6 246.7 41.9 118.2 152.2 119.2 196.1 147.0 84.3 59.4 61.8 159.8 88.1 175.1 104.8 30.0 75.8 102.8 71.4 62.3 203.4 106.0 206.9 147.4 70.3 103.5 252.5 114.1 137.6 130.3 8.3 4.0 4.5 11.3 11.2 21.1 9.2 22.3 16.6 7.3 5.2 17.2 15.0 0.0 10.5 15.6 4.4 41.7 10.3 5.1 5.3 7.1 6.1 5.1 5.7 6.1 5.5 6.6 6.2 5.1 6.2 12.4 19.2 14.4 4.9 17.0 33.4 26.8 31.0 17.6 15.6 15.1 14.4 33.5 14.3 24.7 18.4 6.2 62.8 14.9 13.3 7.9 25.6 69.9 11.5 14.5 15.7 18.0 81.2 11.2 22.2 62.5 22.0 20.4 13.9 7.0 27.3 10.8 15.0 28.3 18.5 12.0 25.0 16.2 11.7 10.3 83.9 13.1 13.9 10.6 6.5 10.7 24.0 5.2 12.1 11.9 15.8 10.4 16.6 31.3 10.1 12.5 8.4 15.5 22.7 13.1 19.5 27.1 102.8 63.1 36.5 29.0 39.7 23.2 18.1 34.3 20.6 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 SAAL1 FLJ41463 ENSG00000166788 "Serum amyloid A like 1" Q96ER3 11 18069935-18106087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039003, HPA039004" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039003: AB_2676303, HPA039004: AB_10673602" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (4.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.88e-1)" "unprognostic (5.76e-2)" "unprognostic (4.10e-3)" "unprognostic (1.53e-2)" "unprognostic (4.75e-2)" "unprognostic (7.26e-2)" "unprognostic (3.36e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.78e-5)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (3.72e-1)" "unprognostic (1.87e-1)" 6.0 5.3 4.9 8.2 4.8 19.1 10.0 5.6 6.1 6.2 4.3 9.6 8.0 7.5 7.7 6.6 5.6 4.8 6.5 4.6 5.0 5.4 8.3 4.9 14.6 4.8 5.3 8.2 8.1 5.4 5.2 7.0 4.9 6.0 11.9 8.2 5.6 5.8 5.8 5.7 6.7 9.6 4.8 7.5 6.7 12.8 5.1 13.7 6.1 7.2 15.6 7.8 6.1 5.7 27.1 41.5 29.5 40.5 19.5 21.8 24.6 29.9 20.4 44.8 52.8 57.8 10.1 73.0 15.5 16.9 62.3 34.9 56.9 48.5 62.6 32.5 57.4 33.6 24.9 35.0 15.9 57.1 28.6 15.2 22.2 28.7 42.9 16.8 38.5 62.8 50.5 23.9 37.2 36.2 66.7 54.2 38.5 41.7 39.0 65.7 51.8 25.4 25.7 31.4 36.4 34.3 26.9 28.4 36.4 37.1 18.2 25.9 15.8 51.0 35.0 29.4 43.2 11.6 37.7 80.6 21.2 45.2 47.5 11.1 12.9 4.3 14.0 15.4 13.5 16.5 16.2 12.3 22.3 11.7 12.3 13.3 0.6 10.4 14.6 11.4 20.9 10.8 4.9 4.8 5.6 6.1 4.6 5.0 4.8 5.3 4.9 4.8 5.1 5.7 7.6 0.0 10.8 7.5 15.9 4.6 7.8 16.0 9.6 9.0 7.2 6.9 8.5 2.8 7.4 1.8 2.1 22.0 13.6 6.3 5.9 9.6 21.9 4.4 8.0 8.7 28.1 11.1 8.5 10.2 23.1 8.0 4.6 4.2 14.0 15.3 5.7 4.6 16.1 0.0 9.5 10.7 8.2 10.9 7.3 3.5 8.1 7.7 5.4 6.5 10.7 6.5 4.1 15.1 11.7 6.6 7.5 7.9 17.3 3.8 6.9 7.7 6.0 8.5 6.6 6.1 10.5 41.5 24.9 8.3 5.4 10.4 9.9 10.1 15.1 6.1 SAC3D1 "HSU79266, SHD1" ENSG00000168061 "SAC3 domain containing 1" 11 65040901-65044828 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 94.1;Late spermatids: 121.5;Spermatocytes: 166.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042677 Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA042677: AB_10797506" "unprognostic (1.35e-1)" "unprognostic (5.45e-3)" "unprognostic (5.00e-1)" "unprognostic (8.01e-2)" "unprognostic (3.56e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (9.67e-6)" "unprognostic (4.11e-1)" "unprognostic (1.70e-1)" "unprognostic (4.45e-2)" "unprognostic (4.71e-2)" "unprognostic (3.20e-1)" "prognostic unfavorable (5.66e-5)" "unprognostic (2.97e-3)" "unprognostic (5.71e-1)" "unprognostic (4.53e-2)" "unprognostic (2.49e-1)" 3.8 3.4 9.9 2.7 9.5 4.1 2.0 9.6 10.6 3.1 7.5 3.6 3.1 3.1 0.6 3.6 2.8 0.7 2.6 9.8 9.1 2.1 3.7 2.1 2.8 11.7 9.9 2.5 2.8 1.3 2.7 1.4 10.7 2.8 1.2 0.6 2.7 2.0 9.3 3.7 2.6 2.0 9.4 3.1 2.9 13.5 10.4 7.1 1.4 2.1 2.1 2.6 2.5 10.2 48.3 27.4 13.3 15.1 6.8 5.0 18.9 28.2 6.3 15.9 13.8 13.4 11.3 20.8 22.2 7.7 17.6 32.1 14.4 15.6 2.7 33.0 44.9 15.5 24.5 42.3 5.1 14.5 11.6 3.9 13.4 12.2 5.4 4.4 5.5 20.3 25.7 16.3 6.1 32.6 39.7 75.9 12.1 13.5 61.2 38.0 19.4 31.7 6.8 10.6 29.9 19.6 21.9 22.2 19.4 3.8 20.8 15.3 6.7 13.6 36.9 37.8 20.0 35.6 30.8 22.7 8.0 15.2 4.5 0.0 1.4 0.2 0.6 1.1 0.5 0.9 0.9 0.7 0.7 1.1 1.0 0.6 0.1 0.2 1.5 1.6 0.9 0.4 9.9 9.5 9.6 10.6 9.8 9.1 11.7 9.9 10.7 9.4 10.4 10.2 7.6 3.2 0.5 3.6 7.1 8.7 5.4 2.5 15.9 6.9 19.0 22.7 5.8 11.5 1.5 9.2 0.0 21.9 11.2 26.3 7.9 3.1 94.1 6.4 13.6 6.4 7.2 16.2 4.0 1.6 42.9 10.7 8.2 7.1 5.7 28.0 5.3 17.9 30.4 5.0 4.2 18.5 0.0 15.1 5.5 121.5 17.7 10.4 10.6 1.0 10.5 13.6 13.4 2.5 5.5 2.4 15.2 13.9 11.3 11.2 14.5 14.7 1.3 9.3 0.0 8.1 10.6 166.7 42.2 20.1 7.7 6.7 11.1 22.2 27.6 3.9 SAE1 "AOS1, FLJ3091, Sua1" ENSG00000142230 "SUMO1 activating enzyme subunit 1" Q9UBE0 19 47113274-47210636 "Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 151.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041906, HPA043552" Supported Enhanced Nucleoplasm,Cytosol NA NA 37000 "Cluster 32: T-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "HPA041906: AB_2677735, HPA043552: AB_2678548" "unprognostic (9.69e-3)" "unprognostic (1.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.49e-8)" "unprognostic (9.86e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.15e-5)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.27e-1)" 43.9 34.7 33.1 18.7 33.9 21.5 38.9 30.2 39.9 47.8 29.7 115.7 9.9 58.5 4.9 53.0 44.5 14.7 44.3 34.2 34.3 29.4 32.4 39.5 23.1 33.4 33.5 36.4 29.3 22.1 27.2 21.6 33.4 38.5 15.8 11.0 31.0 22.3 53.6 41.3 43.2 27.6 30.5 51.8 59.1 76.6 35.6 36.5 50.8 17.7 24.9 68.1 42.3 34.4 126.7 71.6 189.2 81.8 57.9 68.8 51.3 180.7 130.3 154.7 192.7 76.0 61.6 131.4 72.6 112.0 89.6 49.4 179.6 93.2 141.0 138.4 172.0 117.4 45.2 62.7 68.4 142.3 81.7 64.0 42.2 75.4 72.0 58.9 142.2 141.3 138.7 51.3 135.9 68.0 127.1 396.8 87.3 116.0 68.5 171.7 110.2 47.9 56.2 77.1 59.9 79.3 126.8 87.9 79.3 84.3 70.8 75.9 72.7 71.0 103.8 47.0 161.9 97.0 352.1 206.5 44.7 108.7 98.5 55.3 37.6 21.7 41.6 34.7 45.2 37.2 50.4 43.2 45.2 29.6 69.9 54.6 18.9 63.8 23.6 30.1 69.4 65.3 33.1 33.9 30.2 39.9 34.2 34.3 33.4 33.5 33.4 30.5 35.6 34.4 29.2 9.6 18.7 11.4 24.1 25.6 32.6 33.2 16.5 20.1 19.2 16.3 21.9 15.7 18.6 12.9 6.2 77.7 20.5 18.5 11.7 41.6 13.1 13.3 34.4 39.4 19.2 36.6 20.9 34.9 107.2 30.8 17.3 22.0 15.2 40.2 22.1 21.0 57.6 20.2 21.8 25.2 42.7 17.2 25.0 19.1 15.5 19.2 46.2 10.3 48.5 25.8 41.2 10.6 16.3 38.1 20.1 18.8 26.3 32.6 11.4 15.6 7.2 16.6 52.6 16.5 39.0 151.3 113.7 22.4 24.6 57.5 33.5 35.4 32.5 30.5 SAPCD2 "C9orf140, p42.3" ENSG00000186193 "Suppressor APC domain containing 2" Q86UD0 9 137062127-137070557 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1;esophagus: 8.5;skin 1: 6.2" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 10.8;Oligodendrocyte precursor cells: 29.7;Undifferentiated cells: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 122.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044154 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "HPA044154: AB_10959464" "unprognostic (3.68e-2)" "unprognostic (9.85e-2)" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.80e-2)" "unprognostic (1.27e-1)" "unprognostic (5.42e-8)" "prognostic unfavorable (5.88e-4)" "unprognostic (8.33e-2)" "unprognostic (7.47e-2)" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (9.83e-7)" "unprognostic (4.37e-3)" "unprognostic (4.62e-1)" "unprognostic (3.82e-2)" "unprognostic (1.35e-2)" 0.5 0.3 6.9 2.4 5.1 2.0 1.3 4.7 5.4 1.2 1.3 3.7 4.3 0.4 0.0 8.5 0.3 0.2 0.2 5.4 4.5 1.2 0.2 0.5 2.7 7.1 6.8 0.1 0.4 0.0 0.5 0.9 5.7 3.1 1.8 0.1 4.1 0.1 0.1 6.2 4.3 0.4 5.0 2.2 2.4 0.5 6.8 2.3 0.3 0.0 2.5 0.4 2.3 7.0 52.1 27.5 10.7 32.0 0.3 0.7 57.1 8.4 5.7 8.8 4.1 52.5 23.2 53.8 26.5 4.1 8.2 72.3 33.6 9.7 2.0 37.4 38.9 23.6 32.7 59.6 0.2 27.0 39.2 0.1 1.5 3.0 5.8 2.3 14.4 27.1 33.1 23.7 2.6 122.1 7.8 72.7 19.9 119.2 61.9 82.9 40.7 60.1 10.9 14.8 55.2 32.7 32.2 89.1 12.2 2.4 71.9 51.1 9.4 7.9 26.6 24.0 41.9 8.2 25.5 26.3 18.4 31.8 25.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.9 5.1 4.7 5.4 5.4 4.5 7.1 6.8 5.7 5.0 6.8 7.0 0.5 0.0 0.0 0.7 1.9 4.2 0.7 0.5 0.6 0.2 5.0 5.2 1.3 0.0 1.1 0.0 0.0 2.8 1.6 5.4 1.9 0.3 0.0 1.6 0.8 0.9 0.0 3.6 0.2 0.0 3.5 1.1 6.1 6.0 0.0 3.3 1.4 0.0 3.1 0.0 0.2 10.8 0.0 2.8 1.5 0.1 0.0 2.2 0.0 0.0 1.5 0.5 0.0 29.7 5.6 0.6 4.0 0.0 1.8 2.1 0.5 0.0 0.1 0.6 0.0 0.2 1.0 0.0 1.4 5.8 2.7 0.5 1.3 0.6 12.1 1.1 SASS6 "DKFZp761A078, FLJ22097, SAS-6, SAS6" ENSG00000156876 "SAS-6 centriolar assembly protein" Q6UVJ0 1 100083563-100132955 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028187 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA028187: AB_10602220" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (3.07e-2)" "unprognostic (2.06e-2)" "unprognostic (1.31e-1)" "unprognostic (3.02e-3)" "unprognostic (1.21e-4)" "unprognostic (1.27e-1)" "unprognostic (8.43e-3)" "unprognostic (4.73e-2)" "unprognostic (6.56e-2)" "unprognostic (3.71e-2)" "unprognostic (7.76e-8)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (1.20e-1)" "unprognostic (2.54e-1)" 1.3 1.2 1.0 2.9 1.2 6.0 2.8 1.6 1.5 1.6 0.8 2.2 2.8 2.0 2.2 2.1 1.4 1.0 1.0 0.8 1.0 1.0 1.4 1.3 4.2 1.1 1.2 1.8 1.4 3.9 1.6 2.0 1.1 2.1 3.0 5.7 1.8 1.5 1.3 2.1 2.2 1.8 1.1 2.1 2.1 6.7 1.0 4.3 1.5 0.9 3.6 1.4 1.6 1.3 17.0 5.2 13.1 11.5 1.5 2.6 19.3 10.7 4.7 13.5 15.6 9.0 8.5 18.5 8.0 3.7 8.0 14.8 18.0 6.5 18.6 8.9 17.8 16.2 10.9 11.3 0.9 26.8 14.5 1.3 2.8 11.4 9.0 2.7 7.3 12.2 25.8 17.6 6.7 4.8 22.2 12.9 17.5 11.1 10.7 16.1 25.9 9.4 6.5 8.1 9.5 14.0 9.9 17.0 8.7 9.4 8.6 15.9 3.8 9.5 11.6 10.9 14.9 7.4 18.5 24.6 7.7 17.7 5.3 3.9 0.1 1.0 0.7 0.6 0.9 1.6 0.8 0.7 0.5 0.7 0.7 0.6 0.7 0.6 0.5 0.2 0.9 0.3 1.0 1.2 1.6 1.5 0.8 1.0 1.1 1.2 1.1 1.1 1.0 1.3 7.2 0.0 2.3 8.5 12.8 4.0 2.8 7.1 6.8 19.4 8.4 9.4 2.9 7.2 5.9 1.8 16.7 13.6 13.5 2.4 1.9 7.5 15.7 7.4 5.8 5.8 4.2 33.2 7.6 5.6 17.3 7.0 7.1 5.4 5.7 15.0 6.8 3.1 9.1 8.4 9.6 4.8 14.2 8.4 4.7 6.2 8.1 5.8 1.8 5.6 6.1 13.3 20.6 5.0 16.1 6.2 2.7 10.9 19.7 4.5 2.2 4.3 4.9 23.0 0.0 12.6 5.9 77.4 36.0 11.9 4.1 5.1 7.9 4.0 8.8 2.1 SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 13.0;testis: 6.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 16.5;Extravillous trophoblasts: 42.6;Granulosa cells: 20.3;Hofbauer cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 10.0;memory B-cell: 8.8;naive B-cell: 8.9;plasmacytoid DC: 4.1;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Enhanced Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214" "unprognostic (6.87e-3)" "unprognostic (5.01e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.51e-2)" "unprognostic (4.10e-2)" "unprognostic (2.55e-6)" "unprognostic (9.49e-3)" "unprognostic (2.45e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-4)" "unprognostic (1.52e-2)" "unprognostic (0.00e+0)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-1)" "unprognostic (1.64e-1)" 0.3 0.1 0.3 3.3 0.7 8.7 0.5 0.9 0.5 0.4 0.0 2.1 2.3 0.4 0.0 1.9 0.1 0.4 0.1 0.3 0.4 0.3 0.6 0.3 6.2 0.8 0.6 0.2 0.1 0.2 0.0 1.7 0.6 0.2 2.8 0.1 0.4 0.1 0.1 1.1 2.5 1.0 0.3 1.4 1.5 6.7 0.6 13.0 0.2 0.0 6.6 0.9 0.7 1.2 20.3 23.9 29.9 18.5 1.4 2.6 20.2 21.3 10.1 31.2 33.6 16.5 24.0 30.7 10.6 8.6 21.2 11.4 28.7 11.3 37.6 40.9 19.6 34.6 15.6 12.8 0.2 32.0 28.8 0.3 0.9 33.3 13.1 4.0 18.5 34.9 31.3 52.2 24.6 19.4 52.4 15.4 30.0 20.3 17.0 31.8 38.4 17.7 7.5 14.9 14.2 15.4 23.6 27.2 13.1 22.7 18.2 21.3 4.7 22.5 27.3 20.5 43.3 22.8 57.4 35.2 12.5 31.1 35.0 10.0 0.1 1.4 0.2 0.2 0.1 8.8 0.6 0.7 0.3 8.9 0.2 0.3 1.4 0.3 0.2 4.1 2.6 0.6 0.3 0.7 0.9 0.5 0.3 0.4 0.8 0.6 0.6 0.3 0.6 1.2 0.1 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.0 3.4 0.0 0.0 0.0 1.8 0.0 16.5 1.5 0.0 0.0 1.1 0.0 2.3 1.6 1.2 0.0 0.0 0.0 1.8 42.6 3.3 0.0 2.9 1.3 20.3 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.9 1.0 4.3 0.0 0.0 SGO2 "FLJ25211, SGOL2, TRIPIN" ENSG00000163535 "Shugoshin 2" Q562F6 2 200510008-200584096 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9;testis: 32.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.6;Endometrial ciliated cells: 12.1;Extravillous trophoblasts: 31.0;granulocytes: 11.4;Granulosa cells: 23.4;Hofbauer cells: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035163, HPA040817" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA035163: AB_10602397, HPA040817: AB_2677149" "unprognostic (3.43e-1)" "unprognostic (1.70e-1)" "unprognostic (7.06e-3)" "unprognostic (6.71e-3)" "unprognostic (1.90e-1)" "unprognostic (1.77e-1)" "unprognostic (7.55e-6)" "unprognostic (1.12e-2)" "unprognostic (1.98e-3)" "unprognostic (4.87e-2)" "unprognostic (1.37e-4)" "unprognostic (9.49e-2)" "unprognostic (8.07e-9)" "unprognostic (5.21e-2)" "unprognostic (5.43e-2)" "unprognostic (9.86e-2)" "unprognostic (2.02e-1)" 3.3 0.9 0.6 4.4 0.9 6.8 1.9 0.8 0.9 0.9 0.3 3.1 2.5 1.8 0.7 2.4 1.4 1.2 1.0 0.5 0.9 0.9 0.8 1.5 7.9 0.9 0.9 1.9 0.5 1.1 0.3 2.6 0.9 1.4 3.2 0.9 0.7 0.7 0.4 2.3 2.6 2.0 0.7 2.0 1.8 32.6 0.9 14.9 1.2 0.6 8.1 1.5 0.9 1.2 34.6 16.2 37.0 17.4 5.2 7.9 23.7 38.7 16.6 32.0 33.1 24.3 23.5 22.5 18.6 18.1 34.4 25.3 33.6 20.1 54.5 48.0 16.9 43.5 21.6 17.5 1.6 43.9 33.1 3.4 2.5 32.9 17.3 8.0 29.4 31.3 33.1 31.6 61.4 15.4 35.9 17.9 26.7 24.9 41.2 28.8 49.1 21.3 13.3 13.6 22.2 15.4 28.6 13.3 16.3 29.2 14.1 25.2 18.1 33.9 34.0 31.6 34.0 14.3 33.5 49.8 21.4 28.9 49.4 16.7 1.4 4.5 2.2 1.4 1.4 2.7 2.4 2.2 0.8 3.2 1.8 2.2 1.0 2.0 1.7 1.7 3.6 1.2 0.6 0.9 0.8 0.9 0.5 0.9 0.9 0.9 0.9 0.7 0.9 1.2 9.4 3.2 3.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.8 7.1 0.0 0.0 6.2 0.0 0.0 11.6 7.8 0.0 3.9 3.9 0.0 12.1 5.3 3.3 0.0 0.0 0.0 2.7 31.0 6.7 0.0 3.6 11.4 23.4 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 1.7 0.0 0.0 2.5 8.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 3.4 3.8 4.0 0.0 0.0 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.2;Extravillous trophoblasts: 28.7;Plasma cells: 38.3;Spermatocytes: 33.7;Spermatogonia: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 0.7 0.5 0.5 5.1 0.5 17.4 0.9 1.2 0.6 0.6 0.4 1.9 1.2 0.6 0.6 3.5 0.2 0.6 1.0 0.4 0.2 5.4 0.2 1.0 9.8 0.4 0.3 0.3 0.2 0.2 0.2 2.4 0.4 0.3 2.2 0.2 0.8 0.2 1.5 3.3 1.5 1.7 0.1 4.4 0.9 5.2 0.5 8.8 0.3 0.2 10.6 1.2 1.2 0.7 33.8 30.8 11.9 15.3 3.1 6.2 16.2 60.7 24.6 59.2 26.8 14.6 20.8 28.0 30.2 28.8 26.8 21.0 29.3 21.7 73.8 17.7 17.2 28.2 25.8 30.3 0.1 28.5 35.4 1.2 1.6 45.9 18.1 5.9 33.0 14.9 12.7 28.3 69.7 21.5 24.0 23.7 10.0 17.2 31.6 45.4 89.9 44.8 13.7 9.4 5.0 7.2 46.0 23.7 11.1 11.4 13.0 23.4 16.1 43.9 28.7 43.5 54.0 24.9 36.7 46.7 21.4 31.3 45.8 0.2 0.3 0.6 0.2 0.5 0.0 1.7 0.3 0.1 0.3 1.2 0.0 0.1 0.4 0.1 2.4 0.7 1.2 1.1 0.5 0.5 1.2 0.6 0.4 0.2 0.4 0.3 0.4 0.1 0.5 0.7 0.2 0.0 1.1 1.3 7.1 1.7 0.7 1.2 0.0 0.3 0.6 1.1 1.9 1.5 1.4 0.0 0.0 11.3 0.8 1.9 0.0 0.2 8.4 0.7 1.7 1.7 0.0 36.2 2.1 0.0 28.7 3.7 4.1 1.5 0.0 7.6 1.8 0.3 12.6 0.0 0.7 2.2 2.0 4.5 3.3 2.3 0.6 4.0 1.8 2.8 2.8 0.8 0.0 1.0 0.5 0.1 0.1 0.4 38.3 0.5 0.4 0.1 0.1 0.3 0.0 0.5 6.3 33.7 23.7 3.6 0.6 3.7 2.2 0.8 3.4 1.1 SIVA1 "CD27BP, SIVA, Siva-1, Siva-2" ENSG00000184990 "SIVA1 apoptosis inducing factor" O15304 14 104753147-104768494 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 506.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065398, HPA066693" Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA065398: AB_2685484, HPA066693: AB_2685703" "unprognostic (1.86e-1)" "prognostic favorable (5.95e-4)" "unprognostic (1.61e-1)" "unprognostic (1.51e-1)" "unprognostic (6.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.77e-3)" "unprognostic (2.89e-1)" "unprognostic (2.17e-2)" "unprognostic (7.19e-3)" "unprognostic (5.85e-3)" "unprognostic (3.21e-2)" "unprognostic (4.94e-2)" "unprognostic (3.06e-2)" "unprognostic (4.08e-1)" "unprognostic (3.51e-1)" "unprognostic (7.43e-2)" 79.8 64.3 36.0 28.4 37.7 102.2 80.8 36.1 60.4 95.9 43.3 108.3 39.8 78.5 9.0 76.1 86.2 24.2 104.6 35.0 36.8 79.6 155.7 65.1 39.6 39.0 36.5 94.4 103.9 16.0 94.2 27.5 36.5 87.8 7.1 3.1 63.2 37.0 168.8 65.5 73.8 10.5 38.3 83.3 91.1 102.7 40.8 69.7 82.9 35.5 12.7 85.4 78.0 38.9 143.3 233.6 58.9 94.8 19.4 24.7 157.8 76.5 41.5 92.2 80.3 179.8 124.1 135.9 109.6 27.5 60.3 138.4 23.2 77.2 7.9 106.6 230.9 56.5 129.5 214.6 48.4 98.8 95.3 29.9 34.5 42.1 13.5 13.6 53.8 382.9 57.7 76.1 22.2 506.6 319.6 225.9 85.9 94.1 317.9 186.6 117.8 107.8 20.7 133.3 151.6 76.2 107.3 63.1 106.4 9.4 123.5 103.0 58.6 74.4 92.8 176.4 124.8 61.0 71.0 161.9 85.6 112.3 84.7 210.7 139.5 255.0 140.4 171.6 159.5 205.1 167.3 154.6 107.5 195.3 182.3 156.1 134.0 102.7 188.2 502.3 195.3 193.9 36.0 37.7 36.1 60.4 35.0 36.8 39.0 36.5 36.5 38.3 40.8 38.9 127.0 60.9 126.7 8.1 109.3 116.5 213.0 188.9 92.8 38.7 178.1 261.1 54.6 107.2 130.2 103.0 12.5 297.4 147.9 145.0 138.9 91.2 241.3 103.3 88.9 109.6 91.1 148.5 6.3 170.9 345.1 139.8 63.7 74.3 145.1 127.9 163.1 221.0 180.6 38.7 6.3 194.0 103.7 89.7 106.5 54.1 140.8 98.0 108.5 5.6 119.6 143.9 84.5 4.5 9.9 113.2 131.8 124.1 131.3 162.4 201.4 180.2 176.5 45.3 111.7 126.2 143.1 368.9 325.2 112.8 116.9 278.4 115.2 136.3 198.7 218.8 SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.0;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3;Extravillous trophoblasts: 9.2;Plasma cells: 10.0;Spermatocytes: 16.7;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "Karpas-707: 82.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045495 Approved Approved Microtubules NA Yes "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "HPA045495: AB_10960405" "unprognostic (2.18e-2)" "unprognostic (7.85e-3)" "unprognostic (7.66e-3)" "unprognostic (5.93e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (9.60e-8)" "unprognostic (1.03e-3)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "unprognostic (1.18e-4)" "unprognostic (3.91e-3)" "unprognostic (0.00e+0)" "unprognostic (4.50e-3)" "unprognostic (4.66e-2)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" 0.4 0.5 0.9 2.2 0.8 12.0 0.3 2.5 1.1 0.4 0.8 1.6 1.7 0.6 0.2 2.5 0.2 0.3 0.2 1.0 0.5 0.1 0.3 0.4 4.9 1.0 0.9 0.2 0.4 0.1 0.0 1.6 1.2 0.3 2.1 0.4 0.3 0.1 0.6 1.5 1.4 1.1 0.3 1.3 0.8 4.3 1.3 3.6 0.3 0.2 4.8 0.5 0.7 2.4 27.1 10.8 18.6 19.0 1.2 2.1 9.9 30.7 10.6 29.9 28.5 4.7 10.6 21.1 7.6 11.0 25.8 23.6 25.6 13.0 31.4 34.6 2.6 27.0 5.5 18.3 2.3 42.2 26.8 1.5 1.3 20.7 8.2 3.2 20.0 20.0 30.8 82.6 26.4 5.7 34.6 12.1 14.2 6.5 6.4 17.3 18.3 23.5 8.5 1.6 13.7 10.9 17.2 9.9 13.6 15.3 11.4 20.2 10.1 32.8 19.0 12.8 31.8 27.5 41.6 32.4 18.2 34.9 33.3 0.9 0.4 0.1 0.1 0.1 0.1 0.2 0.1 0.5 0.2 0.3 0.2 0.1 0.6 0.6 0.2 0.2 0.4 0.2 0.9 0.8 2.5 1.1 1.0 0.5 1.0 0.9 1.2 0.3 1.3 2.4 0.2 0.0 2.2 0.0 2.8 1.0 0.2 0.4 0.0 0.4 0.7 0.6 0.4 0.0 0.8 0.0 2.1 4.4 0.7 1.6 0.0 0.1 4.5 0.5 0.7 0.4 1.2 22.3 0.2 0.0 9.2 1.4 0.5 1.1 0.0 4.9 2.2 0.1 5.3 0.0 0.1 2.7 0.0 0.8 0.9 2.2 0.3 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 1.1 0.0 10.0 0.4 0.1 0.1 0.2 0.8 0.0 0.2 1.4 16.7 13.5 3.7 0.3 1.5 1.4 0.5 3.4 1.0 SKA2 "FAM33A, FLJ12758" ENSG00000182628 "Spindle and kinetochore associated complex subunit 2" Q8WVK7 17 59109857-59155260 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059235 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA059235: AB_2683953" "unprognostic (2.67e-1)" "unprognostic (6.42e-3)" "unprognostic (9.69e-3)" "unprognostic (5.93e-3)" "unprognostic (2.07e-1)" "unprognostic (4.44e-2)" "unprognostic (7.70e-3)" "unprognostic (9.81e-2)" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (3.96e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.59e-1)" "unprognostic (1.39e-1)" "unprognostic (4.75e-3)" "unprognostic (1.05e-1)" 19.9 12.6 30.8 20.1 33.4 24.2 11.8 43.3 39.5 18.4 29.1 22.1 18.8 20.3 12.5 24.4 18.1 13.0 34.5 27.8 36.3 21.9 22.4 16.1 33.6 34.3 37.6 16.7 11.5 26.1 14.9 22.9 34.3 16.3 20.0 44.4 10.9 19.9 12.6 13.9 16.8 24.6 37.2 15.8 18.3 12.5 34.4 53.7 25.5 20.4 28.5 20.3 18.1 38.3 217.6 78.6 249.4 85.6 32.4 24.5 76.8 107.1 102.8 163.1 182.5 120.2 122.6 114.1 118.8 87.0 124.3 90.9 162.9 149.3 231.0 197.8 127.4 179.4 142.2 75.1 36.8 142.3 112.5 35.6 63.1 104.8 84.5 64.4 77.2 127.3 114.3 164.5 117.1 297.7 215.4 71.9 66.6 238.3 145.1 114.0 281.3 81.0 121.4 93.2 112.3 96.2 119.1 53.8 66.9 165.4 179.2 112.0 68.0 160.5 153.4 130.5 244.8 111.7 255.6 135.9 85.4 105.3 117.6 26.7 13.1 17.2 18.7 23.5 14.4 18.4 25.6 24.1 15.4 13.7 19.8 22.4 2.4 22.9 38.3 18.3 48.3 12.8 30.8 33.4 43.3 39.5 27.8 36.3 34.3 37.6 34.3 37.2 34.4 38.3 24.8 25.6 18.2 23.2 24.6 21.4 21.6 49.2 25.6 36.1 10.8 17.1 46.3 12.8 26.7 9.2 25.0 62.6 25.8 16.1 39.2 38.3 20.8 22.4 30.2 26.9 10.3 96.8 10.9 25.2 61.7 26.9 30.5 21.0 18.3 26.6 25.4 33.0 46.3 50.5 20.1 23.0 14.2 37.0 22.6 9.4 27.1 28.2 23.2 15.0 42.9 49.3 39.1 15.1 26.3 31.9 24.7 25.6 52.0 8.9 12.8 32.1 26.8 39.4 0.0 13.8 41.5 38.8 30.7 34.1 13.5 30.9 35.0 33.8 35.2 18.9 SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.1;testis: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Extravillous trophoblasts: 21.0;Spermatocytes: 21.7;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Supported "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle" "Centrosome, Cytosol" "HPA039272: AB_10805359, HPA039356: AB_10805475, HPA061534: " "unprognostic (3.46e-2)" "unprognostic (7.21e-2)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (9.73e-6)" "unprognostic (2.03e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.39e-2)" "unprognostic (0.00e+0)" "unprognostic (2.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.2 2.5 0.2 4.7 0.8 0.1 0.3 0.2 0.0 1.7 1.0 0.5 0.0 1.9 0.2 0.4 0.0 0.5 0.2 0.1 0.2 0.2 4.3 0.2 0.2 0.0 0.0 0.0 0.0 1.6 0.2 0.0 3.0 0.0 0.2 0.0 0.0 1.8 2.1 1.1 0.2 0.7 1.0 6.3 0.3 12.1 0.1 0.1 3.7 0.4 0.5 0.2 26.1 13.0 25.8 20.5 0.9 5.1 19.1 35.0 14.8 42.1 28.7 23.4 27.8 35.6 10.0 19.3 18.5 24.4 34.4 15.2 54.7 30.3 15.9 47.3 7.7 12.7 0.0 39.5 17.7 1.5 1.0 34.9 15.4 4.2 20.7 30.6 26.3 14.2 33.9 21.0 60.7 37.8 27.9 42.8 23.8 36.5 50.3 15.8 12.2 9.9 30.1 11.1 11.8 17.1 8.1 17.9 15.3 33.5 8.7 16.0 23.8 17.0 43.9 9.0 19.7 34.5 4.4 31.1 51.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.2 0.2 0.1 0.3 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.4 0.0 0.0 0.0 2.6 2.0 0.7 2.4 0.0 0.1 0.9 0.8 0.8 0.0 1.8 0.0 0.0 8.7 1.0 2.1 0.0 1.2 6.3 2.8 0.9 1.4 0.0 12.8 0.8 1.3 21.0 2.1 1.5 1.6 0.0 5.8 1.8 0.4 5.5 0.0 0.6 1.8 2.0 1.9 2.9 7.7 1.5 1.6 0.0 1.9 0.8 0.3 3.1 0.0 0.2 1.0 1.6 1.2 8.5 0.3 0.4 0.6 2.0 0.4 0.0 0.3 2.3 21.7 18.2 5.8 2.8 2.2 1.2 0.5 5.0 0.7 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.6;Spermatogonia: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 29.9 26.4 38.6 37.6 40.2 114.2 26.7 38.0 65.7 28.4 34.4 30.6 23.9 27.3 32.9 35.9 27.6 21.9 18.4 40.9 43.6 35.1 33.9 27.2 71.7 36.4 39.1 28.0 24.4 24.0 26.7 42.0 39.3 22.8 30.6 17.1 25.6 25.3 22.6 37.7 25.6 28.8 37.7 28.3 26.9 63.1 41.8 53.5 27.3 19.2 69.5 35.0 28.0 41.1 132.7 53.9 76.6 80.7 65.3 70.0 81.9 120.1 92.5 131.4 133.8 120.3 144.7 180.6 67.4 96.0 150.9 77.8 147.0 103.0 154.1 75.4 98.5 215.9 63.3 123.6 82.6 208.3 102.8 55.0 84.7 98.1 67.3 74.4 76.5 108.8 172.7 170.3 163.2 52.8 314.6 200.6 97.4 136.7 108.6 241.1 126.3 105.3 131.0 99.5 86.1 69.3 95.4 59.6 69.5 96.8 99.0 127.7 66.3 108.0 63.8 116.1 180.4 107.4 192.2 428.3 99.6 176.0 106.0 25.7 65.4 47.5 47.1 49.7 43.3 51.6 59.7 64.8 50.6 37.8 50.6 49.6 95.8 46.3 44.8 42.2 77.9 75.4 38.6 40.2 38.0 65.7 40.9 43.6 36.4 39.1 39.3 37.7 41.8 41.1 35.2 16.0 18.8 7.2 96.3 105.2 96.3 38.8 61.5 19.4 35.9 34.0 8.2 27.1 23.6 36.8 25.0 166.3 80.5 28.8 107.6 50.6 75.9 38.8 34.9 36.1 35.9 146.0 14.6 31.3 51.8 49.1 53.5 55.5 23.5 45.9 30.0 27.0 81.3 25.2 15.1 33.6 44.7 36.8 58.6 41.6 44.1 60.3 65.8 6.5 64.4 27.4 43.3 9.0 14.4 38.7 25.3 44.0 94.2 88.6 22.5 55.4 16.3 13.6 13.1 46.3 43.8 263.6 294.0 84.1 105.8 44.7 96.6 33.2 44.1 76.5 SLX4 "BTBD12, FANCP, KIAA1784, KIAA1987" ENSG00000188827 "SLX4 structure-specific endonuclease subunit" Q8IY92 16 3581181-3611606 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049421, HPA066238" Approved Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cell Junctions, Cytosol" "HPA049421: AB_2680759, HPA066238: AB_2685642" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-2)" "unprognostic (4.62e-1)" "unprognostic (6.08e-3)" "unprognostic (8.28e-5)" "unprognostic (6.52e-2)" "unprognostic (2.49e-1)" "unprognostic (1.56e-1)" "unprognostic (1.97e-2)" "unprognostic (1.50e-1)" "unprognostic (4.32e-2)" "unprognostic (8.39e-3)" "unprognostic (1.20e-1)" "unprognostic (1.43e-3)" "unprognostic (5.74e-2)" 1.8 2.1 2.1 2.9 1.9 3.0 1.6 7.1 2.7 2.1 0.4 2.3 2.2 2.1 1.3 2.4 2.0 1.1 1.9 2.3 2.1 1.9 1.9 2.1 4.1 2.3 2.0 1.6 1.7 1.1 3.9 1.1 1.8 2.3 0.9 1.7 1.6 1.0 2.7 1.8 2.8 1.2 1.1 3.4 2.2 10.6 1.9 2.7 1.8 1.3 2.9 2.1 2.0 2.1 2.7 8.4 5.3 6.7 2.0 2.1 5.6 4.3 2.2 4.9 5.4 4.2 3.3 10.0 4.2 2.2 3.8 6.0 3.6 3.0 2.9 8.4 4.6 6.8 6.5 2.7 1.8 6.7 9.3 1.5 2.2 4.6 2.6 1.2 3.6 5.6 6.7 5.3 3.9 4.7 4.2 5.9 4.5 1.7 3.1 8.2 8.9 2.8 1.9 1.9 4.5 4.1 3.8 2.6 1.3 2.8 6.5 5.2 4.3 5.6 7.8 4.9 5.1 4.8 4.0 11.4 1.8 6.7 5.7 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 2.1 1.9 7.1 2.7 2.3 2.1 2.3 2.0 1.8 1.1 1.9 2.1 2.7 0.0 2.3 4.6 4.5 0.8 0.8 1.1 4.0 8.7 2.0 1.4 1.7 1.5 3.2 0.0 2.1 1.7 3.4 2.0 0.0 1.5 6.5 5.5 4.2 1.8 0.0 6.5 9.5 2.4 1.6 2.4 3.6 4.6 0.0 4.8 1.1 1.4 2.9 0.0 9.3 2.4 2.0 2.9 1.6 2.3 2.1 5.1 0.0 4.7 2.2 2.7 4.1 7.1 5.5 2.0 0.3 1.9 4.0 0.4 2.3 0.6 2.3 10.1 0.0 4.9 2.5 20.0 9.1 2.3 0.6 1.0 4.4 3.0 2.1 0.6 SMC2 "CAP-E, hCAP-E, SMC2L1" ENSG00000136824 "Structural maintenance of chromosomes 2" O95347 9 104094260-104141419 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 25.7" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071309 Approved Supported Nucleoplasm,Nucleoli Yes No 26000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA071309: AB_2686385" "unprognostic (1.51e-1)" "unprognostic (2.01e-3)" "unprognostic (2.26e-2)" "unprognostic (2.23e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-1)" "unprognostic (5.57e-3)" "unprognostic (2.59e-3)" "unprognostic (1.47e-2)" "unprognostic (4.35e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (8.02e-3)" "unprognostic (1.65e-1)" "unprognostic (1.12e-1)" "unprognostic (1.32e-2)" 5.2 4.1 2.8 11.3 4.0 18.4 6.6 4.4 3.3 7.5 1.3 8.2 7.5 6.0 2.6 7.3 4.7 4.0 7.9 2.2 4.0 6.3 4.7 4.5 16.0 4.9 3.7 4.7 3.5 5.7 1.5 6.9 4.1 4.2 8.8 5.6 3.1 4.7 2.2 7.4 7.6 5.4 3.5 7.2 6.1 12.0 3.5 25.7 7.6 5.4 15.9 4.9 3.2 5.0 59.3 45.0 49.4 45.9 10.3 14.9 46.2 53.5 25.4 46.9 39.4 39.3 44.9 112.6 25.2 27.7 40.5 97.6 72.3 34.8 63.2 71.6 30.3 67.9 68.8 25.5 2.7 41.5 65.6 9.8 7.0 63.7 25.7 15.9 33.7 71.2 55.8 89.8 43.0 28.9 109.1 21.3 42.9 47.6 34.8 72.0 141.3 42.2 20.1 21.1 46.5 35.9 63.8 29.6 15.5 20.5 59.5 28.0 27.1 56.8 59.1 79.3 67.9 32.6 118.2 64.6 36.8 59.8 70.3 15.0 2.2 2.5 4.8 5.9 5.4 7.3 4.4 4.8 2.6 7.9 5.0 5.8 0.3 7.0 7.4 4.4 6.0 2.4 2.8 4.0 4.4 3.3 2.2 4.0 4.9 3.7 4.1 3.5 3.5 5.0 19.6 25.6 11.9 6.5 19.9 27.3 16.4 27.6 11.4 39.7 16.6 19.3 45.1 7.2 17.8 16.5 8.4 54.3 15.2 13.7 35.2 18.9 40.0 114.6 21.6 21.4 4.9 95.3 10.2 20.4 93.8 20.2 13.3 16.0 22.2 40.4 21.0 7.6 44.3 28.6 15.5 14.6 26.4 19.8 19.8 24.7 18.6 22.9 7.2 7.5 19.8 15.6 22.6 5.5 18.4 15.6 6.3 12.4 40.9 7.3 10.3 15.0 12.0 19.1 13.1 25.1 37.7 84.5 93.5 27.4 23.2 25.9 18.1 28.1 35.0 14.2 SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 305.8;Spermatocytes: 339.8;Spermatogonia: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 74.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 25000 "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: AB_10603891" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.22e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.54e-2)" "unprognostic (2.18e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (4.20e-5)" "prognostic unfavorable (9.00e-4)" "prognostic unfavorable (8.05e-7)" "unprognostic (3.03e-2)" "unprognostic (4.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" 6.8 6.5 1.0 21.2 2.0 36.3 6.8 1.2 1.7 6.3 1.5 13.2 14.0 7.4 2.3 23.5 4.5 7.6 7.3 0.9 1.9 5.9 7.8 11.8 37.1 1.7 1.4 5.9 7.8 3.8 2.0 16.2 1.6 5.8 14.9 7.7 4.6 5.0 3.6 11.0 15.4 10.1 1.3 14.7 11.8 32.5 1.9 60.6 9.0 6.8 31.6 9.6 4.3 3.2 386.3 72.8 155.0 73.0 31.5 30.9 72.1 181.2 88.8 206.0 176.8 94.4 209.7 236.6 101.9 81.1 140.0 212.5 183.0 95.0 332.4 297.9 113.8 234.7 123.3 33.6 17.3 158.3 182.6 14.6 13.3 114.4 96.5 78.5 94.8 103.2 130.3 272.2 133.9 78.3 183.2 44.4 91.8 106.7 149.3 180.1 238.8 177.3 43.4 54.8 93.7 94.0 141.4 135.1 65.5 76.6 156.9 128.6 84.8 132.2 105.2 119.9 349.8 181.1 192.2 412.0 96.7 166.9 151.9 74.4 6.0 23.6 11.5 8.9 11.4 17.2 18.2 14.3 6.6 15.0 11.4 10.2 10.8 15.3 15.9 11.7 30.3 9.5 1.0 2.0 1.2 1.7 0.9 1.9 1.7 1.4 1.6 1.3 1.9 3.2 24.6 105.8 174.0 3.9 43.7 40.8 18.2 33.1 30.7 14.9 21.5 21.0 41.3 25.8 35.0 35.0 8.4 74.6 54.4 41.4 3.9 20.9 48.6 35.2 27.0 44.8 30.1 305.8 3.5 14.7 138.1 50.7 32.6 36.1 79.1 77.3 38.2 20.4 61.3 0.0 2.9 44.5 24.4 29.7 43.5 28.3 25.1 36.4 17.8 17.8 39.3 9.3 46.4 3.5 30.1 13.5 26.5 48.2 95.9 14.1 25.9 8.6 25.4 25.8 131.5 21.7 73.2 339.8 239.4 58.1 35.7 34.1 58.4 34.6 69.7 19.1 SNRNP25 "C16orf33, U11/U12-25K" ENSG00000161981 "Small nuclear ribonucleoprotein U11/U12 subunit 25" Q9BV90 16 53828-57669 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.6" "Cell type enhanced" "Detected in all" "Distal tubular cells: 156.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 219.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041183, HPA044248" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041183: AB_2677353, HPA044248: AB_2678873" "unprognostic (7.87e-2)" "prognostic favorable (1.95e-4)" "unprognostic (6.04e-2)" "unprognostic (5.03e-2)" "unprognostic (2.04e-1)" "unprognostic (5.99e-2)" "unprognostic (1.17e-1)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (8.99e-2)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.16e-5)" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (1.45e-1)" "unprognostic (6.03e-3)" 15.2 29.3 80.7 20.6 81.4 32.7 16.1 95.2 98.3 14.0 74.4 27.2 12.9 15.9 16.3 20.1 16.0 10.4 85.3 81.7 81.0 25.0 39.2 10.8 32.6 86.3 82.7 19.8 19.7 24.6 30.7 8.7 87.0 19.8 17.5 12.4 22.9 13.8 131.6 10.9 16.5 15.1 81.8 19.0 27.6 11.0 88.0 22.5 17.7 84.5 31.2 17.2 11.9 80.1 50.1 111.2 60.7 70.8 21.2 24.9 29.5 41.4 26.5 90.7 76.1 150.4 47.5 157.3 48.3 34.2 48.6 50.4 111.8 76.2 69.2 57.3 87.8 91.6 155.3 152.9 22.4 168.9 103.9 32.1 27.0 80.8 22.4 19.6 49.6 93.5 139.2 36.5 52.2 236.5 89.5 70.0 72.8 88.4 54.5 141.9 64.6 186.9 48.6 34.7 66.2 42.9 93.4 119.8 20.7 59.0 77.5 80.8 39.3 40.0 49.6 51.8 67.2 37.6 96.9 248.2 21.3 89.5 62.3 15.1 25.5 93.3 14.9 40.3 17.9 74.3 15.1 17.9 49.6 75.1 15.9 16.3 17.2 22.5 35.9 219.7 26.1 23.2 80.7 81.4 95.2 98.3 81.7 81.0 86.3 82.7 87.0 81.8 88.0 80.1 16.5 12.8 14.3 6.8 53.4 18.6 27.2 39.5 14.8 17.9 48.1 51.9 113.0 18.6 29.3 33.1 4.2 54.6 62.3 30.9 156.5 41.6 3.0 27.3 23.8 18.9 44.0 58.5 9.9 51.4 63.3 29.3 30.1 36.9 4.5 62.3 16.4 67.5 114.5 11.8 9.8 34.5 69.2 26.4 59.8 6.5 21.5 36.2 62.2 5.6 94.3 89.0 32.0 4.5 6.5 31.0 44.8 29.7 65.9 31.5 24.0 87.6 53.2 14.5 6.6 29.4 35.7 33.7 44.8 35.8 21.9 26.1 22.4 105.0 53.5 27.7 SNRNP40 "HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57" ENSG00000060688 "Small nuclear ribonucleoprotein U5 subunit 40" Q96DI7 1 31259568-31296788 "Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026527, HPA027345" Supported Supported "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "HPA026527: AB_1858814, HPA027345: AB_2239703" "unprognostic (2.31e-3)" "unprognostic (5.63e-2)" "unprognostic (5.24e-3)" "unprognostic (1.36e-1)" "unprognostic (1.14e-3)" "unprognostic (1.28e-2)" "prognostic unfavorable (4.73e-6)" "unprognostic (2.14e-2)" "unprognostic (2.43e-2)" "unprognostic (2.50e-1)" "unprognostic (1.22e-1)" "unprognostic (8.57e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-2)" "unprognostic (5.93e-2)" "unprognostic (4.31e-2)" "unprognostic (6.24e-2)" 17.9 18.9 10.7 21.2 14.6 30.0 20.7 15.5 12.6 17.7 10.3 20.6 16.4 20.1 21.7 19.1 22.5 13.1 14.2 10.4 12.5 17.6 19.3 15.8 35.4 14.5 13.3 20.8 13.0 18.0 15.9 22.3 15.4 20.1 22.1 19.1 15.0 20.8 20.9 18.5 17.6 21.7 13.7 21.3 16.6 21.2 12.8 40.3 18.0 18.1 40.2 24.0 16.7 20.1 71.6 53.6 95.5 78.6 46.7 38.4 66.2 58.8 57.4 104.7 101.9 76.7 69.8 91.8 56.4 46.1 53.9 66.4 145.7 69.8 105.9 99.2 109.3 135.2 72.1 83.9 58.4 150.0 59.3 36.2 54.7 102.1 75.6 34.4 86.1 80.2 129.0 52.9 60.5 51.6 111.3 87.9 171.6 71.1 76.5 87.3 134.5 71.1 44.2 57.7 65.1 63.6 92.3 47.4 116.2 88.0 47.2 94.9 59.5 57.9 85.2 81.5 112.9 43.5 57.1 126.1 47.1 139.3 96.4 102.8 75.8 82.3 98.6 97.3 113.1 93.8 95.1 98.2 93.0 82.6 101.1 115.1 16.4 110.5 92.0 78.4 110.2 161.1 10.7 14.6 15.5 12.6 10.4 12.5 14.5 13.3 15.4 13.7 12.8 20.1 44.1 3.2 6.1 14.7 51.5 53.0 50.2 90.8 41.5 15.6 24.4 30.6 16.5 21.5 32.5 16.5 18.8 108.7 35.7 11.9 43.0 42.5 7.1 21.0 27.5 39.4 34.8 80.8 23.7 35.9 91.3 38.1 28.5 13.9 34.3 36.2 28.9 22.3 56.2 10.1 24.3 18.6 69.2 20.7 48.6 5.4 26.8 31.5 42.7 15.0 44.7 23.8 44.3 23.6 49.0 36.4 20.2 34.3 40.6 55.0 17.0 45.0 27.6 22.2 32.9 31.0 35.1 105.5 89.7 39.6 54.8 61.3 52.4 45.9 36.9 40.6 SNRPD1 "HsT2456, Sm-D1, SNRPD" ENSG00000167088 "Small nuclear ribonucleoprotein D1 polypeptide" P62314 18 21612314-21633524 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040516 Supported NA NA 480000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "HPA040516: AB_10673236" "unprognostic (1.83e-2)" "unprognostic (1.81e-1)" "unprognostic (7.85e-2)" "unprognostic (7.52e-2)" "unprognostic (2.18e-1)" "unprognostic (7.61e-2)" "prognostic unfavorable (1.82e-5)" "unprognostic (5.59e-2)" "unprognostic (2.15e-3)" "prognostic favorable (7.90e-6)" "unprognostic (1.87e-2)" "unprognostic (7.39e-2)" "unprognostic (3.87e-3)" "unprognostic (3.33e-2)" "unprognostic (2.06e-1)" "unprognostic (7.36e-2)" "unprognostic (3.83e-1)" 45.9 35.7 33.1 54.5 32.6 94.6 39.0 34.4 51.8 37.1 31.0 48.8 42.2 37.3 26.4 67.0 33.6 23.0 33.0 32.6 34.0 52.3 37.7 33.1 72.6 32.6 34.0 42.0 29.9 23.5 41.9 36.5 33.5 33.1 44.2 33.0 35.0 17.8 48.7 39.6 44.9 28.4 32.8 43.7 36.6 45.0 32.8 79.3 28.9 24.8 71.6 47.3 41.4 33.7 246.1 123.1 377.9 184.5 59.1 49.4 174.4 264.5 85.4 176.9 170.4 234.4 125.5 328.0 214.6 102.7 245.2 231.2 246.0 167.7 191.3 210.4 201.4 276.3 193.1 284.2 78.5 673.4 232.5 52.9 92.1 173.1 156.1 122.0 96.8 327.9 286.5 178.5 120.4 179.7 436.3 470.2 297.7 468.0 214.2 345.1 275.7 351.0 129.9 176.2 235.7 244.4 219.0 165.9 207.3 167.0 120.5 390.7 155.0 179.0 354.4 154.6 455.6 319.8 317.6 671.2 130.4 409.8 203.3 50.1 129.4 48.5 122.5 162.0 134.4 204.4 154.0 152.1 221.4 194.6 160.7 141.6 10.8 137.0 189.7 224.2 193.3 147.3 33.1 32.6 34.4 51.8 32.6 34.0 32.6 34.0 33.5 32.8 32.8 33.7 105.6 80.1 76.3 5.2 123.2 202.5 227.3 343.6 109.8 58.4 116.4 157.6 55.4 111.5 200.4 99.3 12.5 423.3 101.8 101.8 215.2 210.8 15.6 119.2 136.9 138.4 122.8 229.5 12.1 194.3 544.1 132.0 86.2 109.4 100.8 158.7 99.9 113.2 242.9 47.1 12.5 192.1 215.7 106.3 152.5 26.3 108.7 96.9 113.8 6.5 163.6 102.6 117.4 10.1 11.8 236.3 113.2 88.8 122.6 343.1 87.3 214.8 153.4 50.0 98.6 149.0 183.0 282.8 265.2 177.2 221.9 261.9 112.5 161.1 229.8 233.9 SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;kidney: 37.8;testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 126.0;Erythroid cells: 37.2;Spermatocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 11.7;T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 4.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" 2.2 3.3 7.8 7.8 7.6 37.9 2.4 5.8 9.1 2.6 3.4 8.3 7.9 1.9 2.4 8.3 1.7 1.8 1.4 7.6 7.7 37.8 14.8 3.4 14.5 6.7 6.8 2.7 1.5 1.1 4.3 5.7 6.7 2.2 10.7 10.8 2.4 0.8 1.0 5.5 9.1 3.4 5.0 7.4 3.6 74.0 7.7 22.4 8.7 0.7 17.3 2.6 3.6 7.5 84.7 87.7 103.3 78.4 5.2 8.6 42.4 65.9 42.4 98.1 78.3 69.2 25.5 59.8 34.2 46.8 91.7 70.2 114.5 42.7 103.8 108.6 72.9 62.9 87.9 80.2 0.6 83.1 76.1 2.9 3.8 78.6 40.4 14.5 52.1 90.6 69.7 101.5 80.7 52.6 109.4 92.9 54.2 68.3 44.5 72.1 144.4 70.9 29.0 43.0 78.6 45.8 96.4 114.9 31.6 84.9 82.2 70.6 25.7 56.4 91.3 46.6 114.6 46.7 72.9 87.3 37.8 60.6 91.8 11.7 0.0 0.0 0.4 0.4 0.7 0.6 1.2 0.9 0.1 1.4 1.1 0.9 0.2 0.8 0.3 0.3 4.9 0.9 7.8 7.6 5.8 9.1 7.6 7.7 6.7 6.8 6.7 5.0 7.7 7.5 0.5 3.2 1.7 0.7 3.3 2.0 0.9 1.3 1.2 5.0 1.1 1.0 0.7 0.0 1.9 0.0 0.0 9.0 1.3 4.7 1.9 0.5 126.0 6.0 1.1 1.5 13.1 37.2 5.2 0.4 12.2 2.6 5.1 1.8 1.3 12.6 3.3 6.3 6.5 3.3 6.0 4.6 4.1 2.7 4.0 25.2 0.9 6.1 0.0 1.9 0.9 0.7 0.0 2.0 1.7 0.4 4.7 0.0 13.1 0.8 8.1 12.5 7.7 3.9 6.6 2.0 2.2 72.6 21.0 5.2 1.0 3.8 2.8 0.9 5.1 1.1 SPC24 "FLJ90806, SPBC24" ENSG00000161888 "SPC24 component of NDC80 kinetochore complex" Q8NBT2 19 11131520-11155808 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.0;lymphoid tissue: 14.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.0;Extravillous trophoblasts: 15.5;Hofbauer cells: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051234 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA051234: AB_2681397" "unprognostic (1.57e-1)" "prognostic favorable (3.59e-4)" "unprognostic (6.79e-2)" "unprognostic (1.07e-3)" "unprognostic (4.04e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.21e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (6.12e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.62e-2)" "unprognostic (3.52e-2)" "unprognostic (2.25e-1)" "unprognostic (8.82e-2)" 1.9 1.7 1.3 4.8 1.5 26.0 1.2 3.9 2.1 2.1 1.7 4.7 4.5 2.7 0.8 5.0 1.3 2.3 2.7 1.6 1.5 0.8 1.6 1.6 6.3 1.1 0.8 1.3 1.1 0.4 0.4 3.2 1.3 1.6 4.3 1.2 1.3 2.0 4.0 3.9 4.1 8.1 0.5 3.1 2.9 4.3 1.4 14.7 0.9 1.1 6.5 2.5 2.0 2.4 73.6 26.9 36.9 30.1 5.0 9.7 16.6 42.3 15.7 38.6 43.6 28.4 24.6 58.2 46.0 18.5 22.8 38.8 29.0 30.3 28.7 30.9 24.9 78.5 68.9 43.2 1.1 55.5 33.7 1.9 1.1 27.8 12.8 10.0 34.7 62.3 42.8 118.3 27.6 48.7 76.4 32.9 25.5 19.8 43.9 59.8 56.7 18.6 11.2 23.8 38.4 27.2 37.0 22.4 9.6 17.5 22.0 19.8 33.2 36.8 38.3 49.6 51.2 70.5 39.8 55.6 26.9 53.9 30.5 1.9 0.4 0.4 0.5 0.5 0.4 0.8 0.9 1.5 0.2 0.7 0.9 0.6 2.2 2.0 0.5 0.5 1.7 0.3 1.3 1.5 3.9 2.1 1.6 1.5 1.1 0.8 1.3 0.5 1.4 2.4 0.2 0.0 0.5 0.3 1.5 1.1 1.2 1.3 0.0 0.0 1.0 0.4 9.0 1.5 0.8 5.5 6.2 10.0 0.9 2.8 0.0 0.2 0.3 1.0 2.2 2.2 2.4 35.0 0.3 0.0 15.5 3.5 3.6 1.8 5.7 6.5 4.6 0.7 14.0 0.0 0.3 2.6 0.0 3.0 2.5 3.0 0.6 1.0 0.0 1.0 0.0 2.1 2.1 0.5 0.3 0.3 0.0 0.4 6.3 0.3 0.7 0.6 0.2 0.6 0.0 1.3 2.4 6.9 10.8 2.1 0.3 2.1 2.2 0.5 6.6 1.2 SPC25 "AD024, MGC22228, SPBC25" ENSG00000152253 "SPC25 component of NDC80 kinetochore complex" Q9HBM1 2 168834132-168913371 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.5;Erythroid cells: 29.9;Extravillous trophoblasts: 37.9;Muller glia cells: 17.2;Spermatocytes: 26.2;Spermatogonia: 20.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047144, HPA050544" Enhanced Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA047144: AB_2679952, HPA050544: " "unprognostic (3.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (4.74e-6)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.84e-3)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.30e-2)" "unprognostic (1.11e-16)" "unprognostic (9.91e-3)" "unprognostic (1.85e-1)" "unprognostic (3.43e-1)" "unprognostic (1.57e-1)" 0.6 0.8 0.6 0.7 0.6 4.2 1.0 0.3 1.5 0.7 0.5 2.1 3.7 0.5 0.0 4.4 0.3 0.5 0.4 1.6 0.7 1.1 0.8 0.9 3.9 0.6 0.7 0.5 1.3 0.1 0.1 1.1 0.8 0.4 1.6 1.7 1.0 0.0 0.6 1.1 2.1 1.0 0.1 2.1 1.6 3.4 0.6 8.5 0.2 0.1 3.7 0.5 1.5 1.8 1.0 16.8 40.6 22.8 1.8 1.9 14.5 22.9 9.3 23.5 18.1 5.6 16.2 15.7 9.0 3.4 31.9 20.9 15.9 0.0 20.7 10.0 21.5 30.2 7.2 2.2 0.1 20.3 8.9 0.3 1.0 14.3 0.0 4.7 10.3 28.2 0.8 15.7 6.4 9.8 16.1 26.3 0.9 11.2 21.0 28.8 38.1 5.6 9.6 13.7 30.4 0.5 16.8 14.4 3.9 13.5 0.4 16.4 2.5 3.6 42.1 13.4 18.2 31.4 56.0 12.5 4.1 0.5 14.3 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.6 0.6 0.3 1.5 1.6 0.7 0.6 0.7 0.8 0.1 0.6 1.8 0.4 0.0 1.1 0.7 4.2 5.4 1.5 7.1 1.2 0.0 1.5 2.4 0.6 0.0 2.6 0.0 0.0 23.5 1.5 3.7 0.0 0.2 2.0 0.5 1.8 1.6 0.0 29.9 0.3 0.0 37.9 4.6 2.0 1.8 0.0 10.1 2.9 1.2 15.1 0.0 0.5 5.2 2.0 1.9 2.4 1.6 0.6 2.0 0.0 0.0 0.0 17.2 0.0 5.0 0.2 0.5 0.1 1.2 15.3 1.0 1.0 0.2 0.1 0.6 0.0 1.3 4.4 26.2 20.1 7.3 1.4 5.7 2.7 1.7 9.9 2.5 SPDL1 "CCDC99, FLJ20364, hSpindly" ENSG00000040275 "Spindle apparatus coiled-coil protein 1" Q96EA4 5 169583636-169604778 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 38.4;Spermatocytes: 112.9;Spermatogonia: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA044700, HPA048146" Enhanced Approved Cytosol NA Yes "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA044700: AB_2679052, HPA048146: AB_2680284" "unprognostic (2.61e-2)" "unprognostic (1.94e-1)" "unprognostic (8.59e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (4.24e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.48e-6)" "unprognostic (2.63e-3)" "unprognostic (5.70e-3)" "unprognostic (8.27e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.81e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.93e-1)" 3.9 3.6 5.5 9.4 6.0 10.9 5.5 6.1 7.2 3.4 3.4 5.4 5.7 6.2 3.8 5.8 4.4 4.5 3.4 4.7 5.6 4.8 3.2 4.0 14.9 6.0 5.5 6.7 2.5 5.0 2.4 8.4 6.1 3.3 5.7 3.4 3.2 3.1 5.3 5.5 5.3 7.4 7.1 6.6 5.3 35.5 5.4 21.5 4.3 5.9 14.0 4.8 3.8 7.2 57.0 69.2 67.4 47.6 17.6 18.5 59.1 181.1 22.9 128.1 119.0 89.6 38.8 54.3 116.9 147.0 90.3 39.3 56.8 76.0 139.6 58.1 65.2 59.6 117.0 36.2 8.3 66.9 51.3 9.2 6.2 62.2 34.0 29.0 59.9 60.5 41.3 39.3 142.4 58.5 54.1 28.2 50.1 28.9 63.2 64.8 67.6 38.5 89.7 19.8 43.7 31.4 84.9 23.6 34.5 46.9 27.0 44.9 46.3 146.6 46.8 43.4 140.0 30.1 69.2 69.1 35.4 61.9 50.2 4.0 2.7 3.8 8.4 3.6 8.9 11.2 7.9 8.9 2.8 12.7 10.8 9.1 0.5 8.4 6.2 19.7 8.6 4.1 5.5 6.0 6.1 7.2 4.7 5.6 6.0 5.5 6.1 7.1 5.4 7.2 6.1 3.2 6.3 3.9 8.7 4.0 1.7 4.8 4.6 6.9 6.2 7.5 7.1 2.8 7.0 1.8 0.0 14.1 9.8 3.6 5.9 6.6 9.6 5.3 8.0 6.5 1.8 22.3 6.2 4.8 26.1 7.7 12.2 4.9 8.8 38.4 13.2 3.2 12.2 3.3 6.5 3.2 2.0 4.7 3.6 11.1 4.4 4.7 3.6 2.8 5.0 7.4 13.4 5.0 6.8 6.6 1.9 6.4 10.2 1.6 0.5 8.2 4.1 4.4 6.6 6.4 9.9 112.9 59.2 5.8 4.4 4.9 5.2 9.6 7.4 2.5 SSRP1 FACT80 ENSG00000149136 "Structure specific recognition protein 1" Q08945 11 57325986-57335892 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002697 Approved Approved Nucleoplasm,Cytosol NA NA 42000 "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoplasm "HPA002697: AB_1857509" "unprognostic (1.67e-1)" "unprognostic (3.21e-1)" "unprognostic (2.96e-2)" "unprognostic (3.54e-1)" "unprognostic (2.84e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (4.03e-7)" "unprognostic (3.22e-2)" "unprognostic (1.96e-1)" "unprognostic (1.49e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.06e-1)" "prognostic unfavorable (5.63e-4)" "unprognostic (5.92e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (3.52e-2)" 52.3 42.7 37.6 62.9 39.1 78.9 53.7 37.9 46.4 61.0 37.2 64.7 48.3 64.9 47.7 67.7 68.3 37.0 47.0 39.3 41.2 48.8 43.3 51.7 76.1 38.2 38.9 74.1 74.0 60.9 57.4 57.5 37.1 46.6 66.1 36.0 55.0 49.6 140.6 67.0 55.1 58.4 38.5 52.6 59.8 45.8 42.4 87.8 54.0 63.9 91.9 58.6 56.4 40.2 353.0 332.0 308.3 226.9 95.1 105.1 150.7 188.9 181.1 321.8 229.2 230.0 255.2 424.4 196.7 166.7 204.5 264.8 493.7 293.9 402.2 297.7 276.9 271.5 233.1 250.5 149.3 455.4 195.3 106.7 175.7 331.8 456.8 149.1 213.3 320.7 376.0 207.9 222.6 237.1 463.3 400.3 406.1 186.1 201.7 386.1 520.4 412.0 151.7 249.3 321.4 271.6 267.6 226.2 286.7 157.0 275.3 177.0 162.7 218.2 287.1 298.3 328.9 240.9 259.9 431.9 185.0 251.6 294.6 0.8 4.1 4.6 8.6 5.1 8.2 8.4 7.4 9.5 6.0 10.5 8.2 11.0 1.0 7.2 5.2 10.0 9.9 5.0 37.6 39.1 37.9 46.4 39.3 41.2 38.2 38.9 37.1 38.5 42.4 40.2 31.2 76.9 91.2 4.6 51.0 74.9 78.1 52.0 55.8 27.3 38.3 39.8 26.4 44.3 78.1 29.5 25.0 115.6 31.7 29.9 13.7 92.5 83.0 40.8 47.2 52.0 28.8 106.8 10.5 99.4 116.9 45.3 32.1 33.2 41.0 55.6 33.2 39.7 57.5 25.2 9.1 45.2 32.6 37.9 45.5 158.0 42.6 34.9 28.4 8.4 42.5 26.3 40.2 6.0 8.4 69.0 32.9 44.4 72.2 80.0 32.3 25.7 101.0 18.9 19.7 53.1 66.1 58.4 108.0 75.3 76.3 67.6 43.5 46.7 78.4 70.7 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STMN1 "C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN" ENSG00000117632 "Stathmin 1" P16949 1 25884181-25906991 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 951.6;lymphoid tissue: 1343.2" "Cell type enhanced" "Detected in all" "Late spermatids: 2537.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 424.6" "Group enriched" "Detected in all" 5 "dendritic cells: 424.6;T-cells: 143.3" "Cell line enhanced" "Detected in all" "MOLT-4: 3270.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010107, HPA068438" Enhanced Approved Cytosol NA NA 320000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB010107: AB_628297, HPA068438: " "unprognostic (6.30e-2)" "unprognostic (2.40e-3)" "unprognostic (5.31e-2)" "unprognostic (7.94e-2)" "unprognostic (1.89e-1)" "unprognostic (5.02e-2)" "prognostic unfavorable (9.90e-7)" "unprognostic (9.45e-2)" "unprognostic (1.39e-2)" "unprognostic (1.61e-2)" "unprognostic (1.78e-1)" "unprognostic (3.33e-3)" "unprognostic (1.02e-2)" "unprognostic (1.68e-1)" "unprognostic (4.46e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-2)" 56.4 69.1 526.8 103.8 568.0 260.5 60.6 514.2 951.6 57.7 333.6 93.2 70.5 129.8 40.7 115.9 45.2 51.1 56.0 573.2 568.2 77.7 35.8 60.7 253.2 560.1 516.8 172.4 23.2 43.8 103.5 120.1 552.4 31.7 110.6 304.7 43.4 32.7 29.5 56.3 89.1 100.0 537.1 72.8 54.5 387.0 531.7 1343.2 33.6 29.9 246.0 58.9 76.0 791.9 1026.8 226.1 2191.0 882.5 128.9 126.0 225.7 776.3 609.7 1081.9 1037.9 157.2 1018.3 1260.3 426.3 572.0 425.8 304.6 618.6 450.9 1616.1 390.4 310.9 786.0 363.3 547.6 51.9 994.6 529.3 77.0 65.6 439.6 496.8 405.5 833.6 1594.4 1074.4 1203.0 1429.6 268.0 3270.7 1441.5 1350.8 615.1 302.8 1907.9 1709.2 740.7 536.9 91.7 1479.2 1282.3 710.0 348.3 638.4 695.8 500.7 1240.1 406.2 721.8 853.6 634.3 664.8 702.5 1212.0 1535.8 357.7 1904.8 798.2 13.4 4.1 23.5 53.9 8.6 32.2 37.0 47.8 68.2 23.2 45.6 77.8 71.6 1.9 56.3 4.5 424.6 143.3 57.2 526.8 568.0 514.2 951.6 573.2 568.2 560.1 516.8 552.4 537.1 531.7 791.9 257.3 41.7 31.6 32.7 125.1 201.6 148.9 350.0 577.7 454.6 91.0 175.1 77.2 31.5 100.0 174.7 64.6 439.3 261.7 35.1 226.9 148.9 917.2 92.8 100.3 196.3 250.8 505.7 109.5 20.1 604.1 134.9 121.3 141.1 262.0 712.4 109.2 15.4 530.1 195.2 73.0 100.9 567.6 87.3 287.0 2537.2 44.7 130.0 268.6 32.8 32.1 252.4 84.5 38.2 217.4 59.0 69.3 47.0 261.7 63.5 21.0 221.4 59.1 183.6 39.5 68.0 267.6 873.0 260.8 423.9 90.4 130.4 224.9 66.5 177.1 95.7 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TCF19 SC1 ENSG00000137310 "Transcription factor 19" Q9Y242 6 31158547-31167159 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.0;Glandular and luminal cells: 17.6;Plasma cells: 21.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 82.8;GAMG: 47.0;HEK 293: 43.3;JURKAT: 40.9;Karpas-707: 39.2;SCLC-21H: 48.5;U-138 MG: 49.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065994 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065994: " "unprognostic (1.41e-2)" "unprognostic (4.92e-2)" "unprognostic (4.00e-2)" "unprognostic (5.16e-3)" "unprognostic (1.99e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (5.66e-4)" "unprognostic (7.04e-2)" "unprognostic (1.35e-2)" "unprognostic (5.92e-2)" "unprognostic (1.74e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (3.54e-10)" "unprognostic (3.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-2)" "unprognostic (1.21e-1)" 4.6 1.7 0.3 2.6 0.4 1.0 4.3 0.7 0.4 6.9 0.2 5.8 4.4 4.2 2.1 12.5 3.8 0.4 3.7 0.3 0.3 4.1 2.0 4.4 10.0 0.5 0.4 4.8 3.2 0.0 1.3 0.3 0.5 5.1 1.7 0.6 4.7 0.8 2.7 8.9 7.2 1.1 0.3 9.5 5.5 1.9 0.7 0.0 2.4 0.1 1.7 5.2 8.1 0.3 82.8 0.7 0.7 0.1 5.4 7.0 0.7 0.5 0.0 0.1 0.1 5.3 0.1 0.1 17.7 20.1 47.0 0.1 0.0 30.3 0.0 0.5 43.3 7.3 5.1 2.0 0.0 0.2 21.1 2.9 0.0 2.3 0.0 4.4 17.9 40.9 0.1 39.2 8.1 0.3 1.2 13.2 0.1 0.0 0.0 1.1 4.8 0.7 7.1 0.3 48.5 0.5 0.4 0.1 0.5 6.5 0.1 6.0 0.0 49.0 0.2 0.4 0.4 12.5 15.0 24.8 0.1 0.3 0.3 0.0 0.1 0.0 0.2 0.0 1.3 0.5 0.6 1.1 0.3 0.5 0.8 0.2 0.1 0.4 0.0 0.0 1.0 0.5 0.3 0.4 0.7 0.4 0.3 0.3 0.5 0.4 0.5 0.3 0.7 0.3 2.8 3.2 0.6 0.7 6.7 5.1 3.1 2.5 8.6 3.0 2.8 2.9 1.2 0.0 2.5 3.7 0.0 2.9 3.9 1.8 7.9 1.3 0.3 4.7 2.0 4.7 1.2 37.0 0.1 1.8 9.6 5.6 5.6 17.6 1.3 7.0 1.8 0.6 8.9 1.7 0.2 3.9 2.0 2.9 5.4 0.7 5.0 4.8 12.4 0.0 6.0 4.2 8.2 0.0 0.2 1.1 0.9 6.4 21.1 1.3 1.6 0.4 0.2 0.5 0.0 3.5 5.3 0.7 11.1 9.6 3.8 0.4 7.6 2.0 8.8 2.9 TEDC2 "C16orf59, FLJ13909" ENSG00000162062 "Tubulin epsilon and delta complex 2" Q7L2K0 16 2460086-2464963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;testis: 5.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.8;Extravillous trophoblasts: 12.5;Granulosa cells: 6.7;Hofbauer cells: 4.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051394, HPA055389" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cell Junctions" "HPA051394: AB_2681465, HPA055389: AB_2732595" "unprognostic (3.23e-1)" "unprognostic (1.03e-2)" "unprognostic (2.14e-2)" "unprognostic (7.46e-3)" "unprognostic (1.27e-1)" "unprognostic (1.38e-3)" "prognostic unfavorable (2.43e-5)" "prognostic unfavorable (7.58e-4)" "unprognostic (4.04e-3)" "unprognostic (8.85e-2)" "unprognostic (3.74e-2)" "unprognostic (3.72e-2)" "unprognostic (1.16e-4)" "unprognostic (1.28e-3)" "unprognostic (1.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.03e-1)" 0.3 0.8 0.8 1.7 0.9 4.0 0.4 0.4 1.4 0.7 0.2 1.0 1.5 0.4 0.0 2.3 0.3 0.1 0.8 0.8 0.6 0.6 0.8 0.5 2.2 0.7 0.6 0.4 0.6 0.2 0.8 0.9 0.8 0.6 0.7 0.2 0.6 0.2 0.3 0.9 1.4 0.3 0.4 1.2 0.8 5.0 0.9 2.2 0.4 0.0 1.4 0.4 0.8 0.6 10.2 31.3 17.7 20.8 0.3 1.2 17.7 7.9 4.7 12.5 12.1 21.9 8.2 14.0 12.6 3.4 6.8 15.3 12.9 8.0 3.0 15.6 17.4 12.7 23.2 22.9 0.4 12.3 16.3 1.1 1.0 11.0 3.0 1.0 5.8 22.8 21.9 5.2 4.4 19.7 21.6 23.2 39.2 9.7 11.5 52.0 15.1 31.3 2.7 4.4 16.6 27.2 9.1 9.5 7.1 4.7 14.0 14.2 2.2 13.2 19.2 12.8 18.2 11.4 20.1 28.3 6.7 12.3 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.2 0.4 0.1 0.8 0.9 0.4 1.4 0.8 0.6 0.7 0.6 0.8 0.4 0.9 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 0.0 0.0 0.0 0.0 0.0 12.8 0.5 0.0 1.9 2.9 0.0 1.2 1.1 0.6 0.0 0.0 0.0 1.3 12.5 1.7 0.0 1.0 0.0 6.7 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 2.9 0.4 2.7 0.0 0.0 TICRR "C15orf42, FLJ41618, MGC45866, SLD3, Treslin" ENSG00000140534 "TOPBP1 interacting checkpoint and replication regulator" Q7Z2Z1 15 89575469-89631056 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;esophagus: 4.2;lymphoid tissue: 4.2" "Cell type enhanced" "Detected in some" "Erythroid cells: 6.5;Extravillous trophoblasts: 6.0;Granulosa cells: 5.1;Spermatocytes: 5.4;Spermatogonia: 5.3;Squamous epithelial cells: 8.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046746, HPA049454" Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA046746: AB_2732533, HPA049454: AB_2680773" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (3.41e-1)" "unprognostic (1.10e-1)" "unprognostic (6.22e-5)" "unprognostic (7.73e-3)" "prognostic unfavorable (2.87e-6)" "unprognostic (1.64e-1)" "unprognostic (1.31e-4)" "unprognostic (5.87e-2)" "unprognostic (0.00e+0)" "unprognostic (3.54e-2)" "unprognostic (7.38e-2)" "unprognostic (4.53e-2)" "unprognostic (3.59e-2)" 0.3 0.1 0.1 1.0 0.1 3.4 0.3 0.0 0.0 0.5 0.0 0.8 1.0 0.4 0.0 4.2 0.3 0.1 0.1 0.0 0.0 0.1 0.1 0.2 1.4 0.1 0.0 0.3 0.0 0.0 0.1 0.9 0.0 0.2 1.1 0.1 0.5 0.0 0.0 0.5 0.9 0.2 0.1 0.5 0.4 1.5 0.2 4.2 0.1 0.0 1.8 0.3 1.1 0.0 11.0 15.0 19.0 11.0 0.7 1.5 10.7 8.0 3.7 11.0 11.4 16.4 8.4 14.7 4.2 2.6 9.2 21.5 26.3 7.0 10.0 7.4 25.4 21.9 15.5 8.7 0.1 15.8 7.6 0.4 0.5 9.0 6.6 1.6 5.5 12.8 21.3 16.6 6.4 10.4 13.9 13.3 12.7 11.0 7.6 19.6 17.1 11.8 2.6 15.5 8.1 8.0 19.0 10.6 3.1 13.9 7.9 10.5 3.3 11.9 14.8 24.4 16.5 3.9 8.0 12.3 4.1 13.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.2 1.2 0.0 0.3 0.8 1.4 0.0 0.0 0.0 0.0 2.0 0.0 1.4 0.0 0.0 1.7 0.1 0.3 0.3 0.0 6.5 0.4 0.0 6.0 0.5 2.0 0.3 0.0 5.1 0.0 0.0 1.3 0.0 0.6 1.6 0.0 0.0 0.7 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.1 0.0 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 5.4 5.3 8.6 0.1 1.0 0.1 0.1 1.6 0.1 TIMELESS "hTIM, TIM, TIM1" ENSG00000111602 "Timeless circadian regulator" Q9UNS1 12 56416363-56449426 "Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.5;Spermatogonia: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA060655 Enhanced Supported Nucleoplasm No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA060655: AB_2684338" "unprognostic (3.94e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-2)" "unprognostic (2.18e-2)" "unprognostic (2.36e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (1.43e-3)" "prognostic unfavorable (1.06e-5)" "unprognostic (7.03e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (9.47e-3)" "unprognostic (1.72e-1)" "unprognostic (1.92e-2)" "unprognostic (5.01e-2)" 3.4 3.4 1.6 11.0 2.1 22.0 4.5 2.1 2.1 4.1 2.7 6.7 6.0 4.4 2.5 6.8 3.1 3.3 1.8 1.5 2.1 3.8 9.8 4.1 15.3 2.4 2.4 1.9 5.0 5.9 5.4 8.7 2.5 3.2 8.5 13.7 3.9 3.4 3.4 5.5 6.2 5.6 2.1 6.8 5.5 6.2 2.6 19.8 4.7 1.6 17.9 4.7 3.9 2.5 39.4 89.1 111.4 51.9 9.9 9.9 62.8 41.9 25.3 58.3 46.0 45.6 56.5 113.3 41.5 24.5 29.4 32.8 82.0 32.7 53.5 54.2 45.7 86.9 47.6 33.6 5.1 66.2 62.2 6.9 10.3 41.9 25.2 16.0 31.5 67.3 82.7 99.5 49.8 77.2 94.7 51.2 79.2 49.5 36.8 93.5 56.7 55.5 22.7 49.5 85.4 58.9 78.2 43.9 12.2 45.6 77.4 51.8 18.9 45.3 45.1 41.8 35.0 37.3 50.9 62.8 21.1 39.9 55.5 0.1 0.6 0.4 1.8 1.5 0.3 3.3 1.1 1.2 1.0 4.9 0.8 0.3 0.2 1.5 1.1 1.2 1.5 1.1 1.6 2.1 2.1 2.1 1.5 2.1 2.4 2.4 2.5 2.1 2.6 2.5 2.6 0.0 5.0 2.3 8.2 3.3 3.0 3.0 6.8 57.5 3.1 3.4 2.1 2.8 6.8 7.3 2.1 15.9 1.8 2.7 0.0 4.8 6.9 2.5 3.9 5.0 1.8 16.6 0.9 5.7 20.9 3.7 6.6 4.8 5.7 15.5 4.6 10.6 8.5 6.7 1.3 5.2 4.1 2.6 3.7 2.9 1.2 4.6 0.0 1.9 4.2 4.8 4.1 0.5 3.2 3.7 0.6 1.2 18.2 4.2 1.1 2.0 3.4 17.8 0.0 2.7 7.0 1.6 24.5 12.1 1.4 9.2 6.1 3.2 8.5 3.0 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174091-78187233 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Erythroid cells: 108.6;Extravillous trophoblasts: 210.4;Hofbauer cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 34.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in some" "white matter: 3.6" "Low region specificity" "Detected in many" CAB004683 Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (6.87e-4)" "prognostic unfavorable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 3.7 2.7 2.5 20.4 3.4 77.9 5.9 3.6 3.4 5.9 1.3 24.4 18.0 3.0 0.2 27.2 4.9 3.4 2.8 2.7 2.4 11.0 9.2 9.1 34.8 3.4 3.3 1.3 5.6 0.6 0.6 14.8 3.3 3.4 15.7 0.1 6.3 1.5 5.5 14.2 18.3 10.1 2.6 12.4 17.9 3.1 3.8 25.1 2.0 1.6 30.6 5.5 9.0 4.4 443.9 357.7 68.2 92.5 7.6 28.0 47.3 207.6 113.2 323.1 442.3 324.2 178.7 144.1 72.9 131.7 133.9 204.2 63.4 187.1 158.0 51.2 230.4 252.5 119.9 213.3 2.2 107.1 162.9 13.8 7.1 166.1 22.5 22.3 137.9 49.4 156.7 311.9 130.8 352.0 56.0 68.6 36.7 259.1 240.9 152.6 276.4 324.1 90.6 138.5 33.6 94.2 162.0 481.2 59.7 59.4 303.9 156.1 57.8 302.3 305.7 219.9 292.1 132.5 71.4 181.9 149.0 71.9 142.1 0.0 1.1 0.0 1.8 2.1 0.7 5.8 7.9 4.0 3.4 1.7 0.4 2.2 1.8 10.8 1.7 1.1 34.0 5.5 2.5 3.4 3.6 3.4 2.7 2.4 3.4 3.3 3.3 2.6 3.8 4.4 1.6 0.0 2.7 0.0 17.1 28.4 13.3 17.8 2.2 0.0 10.6 9.4 0.9 2.8 8.3 12.9 0.0 92.8 3.6 35.0 7.9 7.7 3.0 9.2 3.3 10.6 5.4 108.6 0.3 11.2 210.4 15.7 19.4 7.0 0.0 15.9 7.5 10.5 65.2 0.0 0.2 32.7 8.2 15.5 19.1 6.8 0.6 10.9 3.6 0.0 5.7 0.0 3.1 0.0 1.0 9.6 7.5 0.7 53.6 4.9 3.1 17.5 5.8 0.0 0.0 1.7 20.1 3.8 16.8 24.7 11.2 51.0 8.7 1.7 60.8 24.0 TMPO "LAP2, LEMD4, TP" ENSG00000120802 Thymopoietin "P42166, P42167" 12 98515579-98550351 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" DNA-binding Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 139.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 172.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008150, CAB009847, HPA070805" Enhanced Enhanced "Nuclear membrane" NA Yes 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB009847: AB_2205450, HPA008150: AB_1079235, HPA070805: " "unprognostic (2.36e-1)" "unprognostic (4.46e-3)" "unprognostic (5.90e-2)" "unprognostic (2.80e-2)" "unprognostic (1.35e-1)" "unprognostic (2.95e-2)" "unprognostic (1.07e-2)" "unprognostic (1.54e-1)" "unprognostic (1.74e-2)" "unprognostic (3.69e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-3)" "prognostic unfavorable (9.34e-4)" "unprognostic (6.01e-3)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (3.26e-2)" 17.1 13.9 8.4 44.0 9.4 93.2 24.3 19.1 15.1 23.2 10.1 34.5 34.1 30.8 34.4 27.0 22.8 17.7 11.0 9.1 9.6 21.7 37.2 21.9 78.7 9.7 8.9 56.2 25.3 17.8 8.4 29.4 9.6 17.2 36.4 20.7 16.5 19.1 12.2 22.7 39.6 22.3 8.8 39.1 35.7 23.1 9.6 139.9 15.2 12.2 78.1 20.7 20.7 14.2 180.5 117.5 283.3 145.5 23.1 30.7 166.2 145.0 77.1 193.9 139.5 129.5 88.9 314.4 86.2 85.6 70.7 113.0 240.8 110.1 177.1 217.7 148.5 269.1 103.3 86.5 21.2 315.4 170.8 17.6 35.4 115.0 61.2 66.9 112.8 192.0 231.8 118.1 122.0 114.7 514.9 248.6 170.1 167.2 108.6 421.3 187.2 218.6 69.3 167.7 221.9 132.2 248.9 155.2 79.3 110.6 174.3 149.2 60.4 111.1 96.5 76.8 150.8 125.9 231.9 344.0 32.0 179.5 151.0 48.6 30.4 13.4 18.9 54.1 20.5 22.4 21.9 21.6 23.4 27.2 30.0 23.5 2.4 20.7 75.9 12.9 28.5 30.5 8.4 9.4 19.1 15.1 9.1 9.6 9.7 8.9 9.6 8.8 9.6 14.2 45.4 32.1 27.9 3.6 70.1 27.8 23.7 18.7 28.5 21.1 21.2 28.6 9.0 25.8 33.5 31.3 12.5 36.0 48.5 63.0 31.3 19.5 42.7 29.5 29.8 38.0 28.7 172.1 20.3 31.5 89.7 32.2 56.1 42.7 29.1 70.1 34.2 50.0 38.2 10.1 15.3 63.4 16.2 63.1 34.9 32.1 28.6 73.4 17.8 23.4 63.5 20.3 54.6 14.6 19.1 26.7 28.5 40.6 81.9 21.1 33.7 33.1 25.6 52.6 19.7 27.3 32.0 54.0 59.4 62.8 23.3 11.8 60.8 32.4 62.4 21.8 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TOPBP1 "Dpb11, KIAA0259, TOP2BP1" ENSG00000163781 "DNA topoisomerase II binding protein 1" Q92547 3 133598175-133662380 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 104.1;Spermatocytes: 81.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022451, HPA036738, HPA036739" Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "CAB022451: , HPA036738: AB_2675280, HPA036739: AB_2675281" "unprognostic (7.72e-2)" "unprognostic (8.54e-2)" "unprognostic (2.77e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.05e-1)" "unprognostic (3.05e-2)" "prognostic unfavorable (4.66e-5)" "unprognostic (8.03e-2)" "unprognostic (3.98e-2)" "unprognostic (2.59e-2)" "prognostic unfavorable (1.88e-4)" "unprognostic (2.74e-3)" "unprognostic (8.65e-3)" "unprognostic (7.97e-2)" "unprognostic (2.52e-1)" "unprognostic (7.64e-2)" "unprognostic (1.60e-1)" 7.7 4.9 3.6 13.0 4.3 33.1 10.7 5.0 4.6 6.5 3.1 9.3 8.3 8.1 5.0 8.9 5.9 6.9 6.1 4.6 3.3 5.5 7.4 7.3 19.7 3.7 3.2 7.3 7.6 6.0 3.6 12.0 3.7 6.6 11.5 8.2 7.1 5.5 6.9 11.8 9.2 8.7 3.5 10.4 8.7 22.4 3.7 29.1 7.4 7.6 18.6 8.3 7.0 4.5 44.4 27.2 43.1 35.1 8.0 10.5 32.3 33.9 26.9 41.0 52.4 37.9 27.5 80.5 29.1 24.7 49.3 50.2 62.8 22.6 62.7 48.9 28.2 75.4 38.3 23.4 7.7 81.5 57.1 12.5 13.7 40.2 23.9 15.4 28.5 46.3 47.6 55.7 32.6 30.3 79.9 43.1 35.7 50.4 23.0 53.3 53.8 58.4 14.6 30.1 40.9 45.2 41.9 22.6 35.4 41.7 37.7 74.6 19.9 43.0 38.9 43.9 37.7 33.4 53.4 150.6 25.4 42.7 38.4 1.8 0.7 2.2 0.7 0.9 1.0 0.9 0.7 0.7 0.7 0.5 0.7 0.7 0.9 1.0 0.5 1.0 1.5 0.4 3.6 4.3 5.0 4.6 4.6 3.3 3.7 3.2 3.7 3.5 3.7 4.5 17.1 22.4 21.9 10.7 22.8 12.4 8.8 7.8 20.5 15.2 14.2 14.2 10.1 12.8 19.7 11.0 2.1 20.0 33.9 11.9 9.8 12.3 69.4 8.8 16.8 16.0 7.2 42.7 24.3 13.3 19.6 14.9 16.3 13.1 7.6 34.3 7.5 9.5 11.2 3.3 19.6 13.9 6.1 16.7 8.0 104.1 10.2 18.2 8.8 11.2 27.4 10.4 28.8 16.6 13.0 14.7 11.6 9.8 37.5 10.2 6.1 6.1 8.7 9.3 13.1 20.9 12.2 81.3 43.6 22.0 11.5 14.0 23.3 17.7 14.8 10.5 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828601-49856574 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 8.2;Spermatocytes: 15.6;Spermatogonia: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA036261: AB_10673348, HPA036262: AB_2675029" "unprognostic (5.30e-3)" "unprognostic (9.41e-2)" "unprognostic (1.48e-1)" "unprognostic (6.50e-3)" "unprognostic (1.88e-1)" "unprognostic (7.68e-3)" "prognostic unfavorable (8.77e-5)" "unprognostic (4.61e-2)" "unprognostic (1.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-2)" "unprognostic (7.97e-2)" "unprognostic (9.01e-5)" "unprognostic (5.84e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" 1.5 1.0 1.6 1.8 2.5 6.8 1.9 0.7 1.8 2.0 0.4 2.3 1.5 1.7 1.4 2.9 1.8 1.0 0.9 1.6 0.9 0.8 0.8 0.9 4.6 0.6 0.6 2.1 1.0 0.8 1.2 1.6 0.7 1.4 2.9 2.3 1.2 0.9 2.0 4.2 2.0 2.1 0.6 1.9 1.2 7.9 1.3 5.3 1.4 1.2 4.4 1.3 1.9 0.9 10.4 12.4 17.4 17.6 1.6 2.4 14.4 12.4 5.8 25.3 24.0 15.2 11.6 25.5 8.5 7.1 17.7 13.4 18.5 14.0 18.8 14.7 12.2 19.2 16.3 13.6 0.7 15.8 15.4 1.6 2.0 20.4 10.7 3.0 6.7 22.3 14.0 17.8 11.4 15.1 26.5 20.1 14.0 12.3 20.3 14.4 11.7 14.8 4.6 14.2 8.4 14.4 13.6 11.3 8.8 12.4 10.2 22.4 5.2 16.1 19.0 22.5 24.4 13.0 33.7 27.3 8.1 21.2 14.6 0.0 0.6 0.3 0.9 0.3 0.9 2.9 0.5 2.1 0.6 1.5 0.7 1.1 0.1 1.2 1.3 0.7 0.3 0.6 1.6 2.5 0.7 1.8 1.6 0.9 0.6 0.6 0.7 0.6 1.3 0.9 0.6 3.2 0.6 1.0 1.8 1.1 0.6 1.5 2.2 2.8 1.2 1.4 2.6 0.0 0.3 3.7 0.0 4.2 1.2 1.8 0.0 2.0 4.3 0.6 0.9 0.8 0.0 3.8 1.4 1.0 8.2 2.0 1.5 0.9 0.0 5.7 1.1 0.7 3.5 0.0 0.9 2.0 0.0 0.8 0.4 4.8 2.5 0.7 1.8 1.0 1.8 1.7 0.0 0.5 0.6 1.1 0.3 1.2 4.3 0.8 0.9 0.3 0.5 3.3 0.0 1.4 1.7 15.6 9.1 2.3 0.3 1.0 1.2 1.2 4.6 0.2 TROAP TASTIN ENSG00000135451 "Trophinin associated protein" Q12815 12 49323236-49331731 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.0;lymphoid tissue: 36.7;testis: 29.1" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Erythroid cells: 75.6;Late spermatids: 70.2;Spermatocytes: 29.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 8.6" "Lineage enriched" "Detected in many" 4 "T-cells: 8.6" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA044102 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "HPA044102: AB_10963691" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.92e-3)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.43e-3)" "unprognostic (2.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.08e-3)" "unprognostic (3.51e-2)" "unprognostic (0.00e+0)" "unprognostic (1.80e-1)" "unprognostic (1.54e-1)" "unprognostic (1.92e-1)" "unprognostic (5.17e-2)" 1.3 1.5 0.2 7.3 0.3 51.0 1.4 0.2 0.7 2.8 0.2 6.7 9.0 1.2 0.5 13.5 0.7 0.8 0.8 0.2 0.2 0.9 1.6 2.4 11.2 0.4 0.2 0.8 0.8 0.7 0.4 5.1 0.3 0.9 9.2 0.6 2.5 0.4 0.3 7.7 7.6 2.8 0.1 7.0 5.4 29.1 0.5 36.7 0.8 0.3 14.5 1.9 5.3 0.3 95.9 73.9 92.4 69.7 2.8 6.2 71.2 45.4 43.4 129.5 73.1 163.7 73.5 64.6 21.9 33.7 70.7 74.6 70.4 44.0 75.7 51.9 101.8 90.9 120.4 53.7 1.9 66.5 93.8 1.5 6.0 86.9 59.8 21.1 75.1 68.0 57.2 108.9 52.7 123.0 122.9 101.8 43.4 269.3 110.2 62.5 78.6 83.9 31.7 35.0 59.9 41.0 56.0 107.4 32.7 53.6 88.2 50.1 25.0 33.5 91.2 69.4 124.8 58.3 68.8 83.0 32.3 73.8 38.4 0.2 0.0 0.1 0.1 0.0 0.2 1.4 2.1 2.3 0.3 1.4 0.1 0.5 0.0 2.0 0.1 0.0 8.6 0.5 0.2 0.3 0.2 0.7 0.2 0.2 0.4 0.2 0.3 0.1 0.5 0.3 0.1 0.0 0.0 0.0 4.6 3.8 1.5 2.8 1.2 0.6 2.1 2.8 0.5 0.0 1.8 0.0 0.0 14.1 1.0 3.7 0.0 0.7 71.5 1.9 1.3 1.9 1.2 75.6 0.0 0.7 23.6 3.3 10.2 2.7 0.0 16.0 5.7 1.1 15.7 0.0 0.0 7.9 10.2 6.7 3.7 70.2 1.8 4.0 1.8 0.0 0.9 0.0 6.2 0.0 0.0 0.8 1.8 0.4 17.0 1.1 0.7 0.1 0.2 0.4 0.0 0.7 3.5 29.1 9.3 15.6 2.0 4.0 2.5 0.9 12.7 3.6 TTF2 "HuF2, ZGRF6" ENSG00000116830 "Transcription termination factor 2" Q9UNY4 1 117060326-117107453 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Transcription termination" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005776, HPA070762" Approved Supported Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA005776: AB_1080416, HPA070762: AB_2686307" "unprognostic (1.82e-1)" "unprognostic (2.18e-1)" "unprognostic (3.29e-3)" "unprognostic (2.01e-3)" "unprognostic (4.90e-2)" "unprognostic (3.41e-3)" "unprognostic (5.27e-4)" "unprognostic (7.96e-2)" "unprognostic (1.92e-2)" "unprognostic (3.33e-1)" "unprognostic (4.64e-2)" "unprognostic (9.52e-3)" "unprognostic (7.34e-3)" "unprognostic (1.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.50e-1)" "unprognostic (3.65e-2)" 3.8 4.7 2.6 6.4 3.9 5.4 4.2 2.8 3.7 3.3 3.6 5.0 4.3 3.0 1.7 5.2 2.6 2.8 3.1 2.4 2.8 2.6 1.4 2.6 7.3 5.4 3.5 2.7 3.5 3.9 2.3 2.7 3.6 2.5 5.4 2.5 3.3 2.5 4.7 4.9 4.0 4.0 3.0 4.3 3.9 4.2 3.8 8.9 3.6 2.3 7.9 3.3 3.6 4.7 27.7 10.0 19.8 28.0 7.7 6.7 24.6 14.5 6.7 20.8 18.3 14.1 4.8 33.4 21.8 9.6 23.2 28.1 35.2 18.7 32.0 25.9 24.8 28.5 19.5 18.2 5.5 42.1 31.5 7.7 7.0 15.4 28.4 5.2 14.4 26.0 22.3 29.6 15.9 42.4 28.1 26.0 30.9 26.3 20.0 40.0 72.7 14.6 12.7 12.4 16.8 7.0 21.7 21.4 8.4 14.9 11.7 17.0 14.6 13.1 27.6 31.0 31.8 13.5 12.5 40.6 8.8 31.2 53.7 0.9 2.3 1.5 1.2 2.8 1.2 1.5 1.4 2.0 2.6 1.5 1.4 1.7 0.4 2.6 1.6 1.4 2.7 1.0 2.6 3.9 2.8 3.7 2.4 2.8 5.4 3.5 3.6 3.0 3.8 4.7 4.4 6.4 6.4 6.8 13.4 13.3 17.1 8.5 12.0 5.7 7.6 6.3 7.3 5.7 7.3 12.9 8.4 9.7 8.9 10.6 5.9 6.6 6.9 8.9 15.6 6.9 4.9 30.3 8.1 8.0 7.6 11.0 8.6 12.3 9.5 24.7 5.7 3.0 11.4 11.8 4.7 8.3 0.0 8.6 12.1 7.0 6.5 14.5 7.2 10.3 22.1 3.3 14.4 2.5 13.5 9.3 5.1 4.1 16.0 22.7 6.2 3.8 5.1 7.2 0.0 18.4 8.5 9.2 12.4 19.4 14.3 3.8 12.3 12.2 13.5 17.9 TUBA1B K-ALPHA-1 ENSG00000123416 "Tubulin alpha 1b" P68363 12 49127782-49131397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 2143.3;Extravillous trophoblasts: 2555.5;Hofbauer cells: 2114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011513, HPA039247, HPA043684, HPA063394" Enhanced Supported Microtubules NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "CAB011513: AB_2210057, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic unfavorable (5.49e-4)" "unprognostic (4.19e-2)" "unprognostic (3.84e-3)" "unprognostic (5.84e-2)" "unprognostic (2.91e-1)" "unprognostic (7.10e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (2.98e-3)" "unprognostic (9.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.69e-2)" "unprognostic (9.46e-2)" "prognostic unfavorable (2.85e-12)" "unprognostic (1.60e-1)" "unprognostic (3.52e-1)" "unprognostic (4.67e-2)" "unprognostic (3.55e-3)" 531.9 319.3 1071.9 650.0 1115.9 1491.9 453.7 941.8 1318.4 306.5 841.2 598.4 279.4 460.5 403.7 550.9 369.1 305.6 509.3 1108.8 1139.4 310.3 233.9 511.3 750.8 1176.0 1108.8 325.9 179.9 262.6 322.2 582.9 1162.2 247.8 665.1 652.9 304.6 394.1 243.9 404.3 352.5 1004.6 993.4 435.8 355.7 322.7 1127.4 1557.3 267.3 242.0 882.3 639.5 339.4 1076.7 3063.5 3381.9 3587.5 2051.4 910.0 1321.7 1939.2 2635.0 2642.5 5018.6 4034.6 4300.0 3144.6 3430.1 1854.8 3732.5 2047.5 1864.3 3993.2 3609.1 4586.7 1938.3 2103.5 2445.9 1822.2 2219.9 251.5 3705.8 1863.3 793.6 540.2 3930.9 1298.9 1697.4 4353.5 3121.3 2788.0 2182.3 4142.7 3362.1 4985.5 2943.8 2504.9 7570.8 3944.4 3980.1 3023.6 2137.4 2377.1 2008.1 2250.7 1921.9 2211.7 1697.3 803.9 1804.3 2403.1 3624.8 2321.3 2393.9 2752.4 2404.5 3470.2 1196.5 1876.2 3685.5 1668.2 2924.3 2303.6 197.9 240.0 411.5 241.8 1022.1 266.7 268.9 230.1 225.3 632.4 239.6 241.0 192.4 271.6 230.9 1107.4 632.0 293.2 731.1 1071.9 1115.9 941.8 1318.4 1108.8 1139.4 1176.0 1108.8 1162.2 993.4 1127.4 1076.7 702.9 198.7 231.8 36.6 445.8 584.0 653.7 875.4 288.5 426.4 267.9 391.8 0.8 90.1 373.4 187.6 492.1 1143.1 514.2 482.6 361.9 814.5 272.5 189.3 218.3 643.9 303.7 2143.3 201.8 630.1 2555.5 603.4 237.0 203.9 542.8 1069.6 353.4 106.3 2114.8 498.0 99.1 508.1 512.7 361.8 1353.1 204.8 326.8 729.8 473.2 68.4 1248.5 455.7 228.6 34.7 82.7 703.3 298.4 236.6 595.9 373.5 240.0 245.1 287.7 970.8 263.0 321.5 957.4 161.6 488.9 560.6 449.8 304.4 480.3 172.4 551.2 539.1 TXNL4B "Dim2, DLP, FLJ20511" ENSG00000140830 "Thioredoxin like 4B" Q9NX01 16 72044289-72094431 "Predicted intracellular proteins" "Cell cycle, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065865 Supported Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA065865: AB_2685571" "unprognostic (1.45e-1)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.55e-2)" "unprognostic (3.78e-2)" "unprognostic (8.72e-2)" "unprognostic (4.75e-2)" "unprognostic (2.65e-1)" "unprognostic (8.91e-2)" "unprognostic (4.75e-2)" "unprognostic (1.04e-1)" "unprognostic (3.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.62e-1)" "unprognostic (2.11e-1)" "unprognostic (1.26e-1)" "unprognostic (1.62e-1)" 9.5 7.2 8.8 9.5 11.1 14.3 9.6 10.7 12.2 8.1 9.9 7.4 10.1 7.7 7.6 9.1 10.1 8.7 8.6 9.5 10.1 8.3 16.2 6.7 11.3 10.7 10.1 20.9 9.1 7.6 8.4 7.5 10.8 7.3 8.2 6.7 8.7 7.4 9.0 8.0 8.5 6.4 10.4 7.4 7.9 15.6 10.5 11.7 8.1 8.3 9.7 7.3 6.9 15.5 14.3 20.8 11.2 15.9 8.2 9.7 25.0 18.1 14.7 31.0 23.3 21.4 12.7 20.6 12.8 9.4 14.5 19.3 20.1 10.9 24.0 10.3 18.9 19.0 16.8 32.7 17.4 22.8 15.9 10.1 7.3 27.5 26.1 12.0 13.5 22.6 46.5 12.2 14.8 26.7 27.6 20.5 20.9 9.0 19.1 28.3 14.2 28.3 11.5 10.6 25.9 22.2 17.0 8.0 24.6 8.6 18.7 14.5 12.9 14.9 21.6 12.5 17.2 23.9 41.8 86.0 16.7 15.4 15.2 25.4 8.8 12.3 7.6 9.8 11.9 9.7 7.9 6.7 7.8 7.1 10.8 10.8 12.6 4.9 14.0 8.5 9.9 9.1 8.8 11.1 10.7 12.2 9.5 10.1 10.7 10.1 10.8 10.4 10.5 15.5 7.1 3.2 8.3 7.5 13.1 8.5 7.7 5.4 9.6 3.7 9.8 10.4 2.0 7.2 5.5 5.5 2.1 13.5 8.9 7.4 5.9 10.7 1.6 10.5 9.7 10.1 9.0 10.8 3.3 10.1 17.5 7.9 7.7 12.5 9.5 16.0 10.8 13.3 12.0 10.1 3.3 9.5 0.0 9.2 4.6 4.5 11.8 9.3 7.2 2.8 10.8 4.5 8.2 7.5 5.8 7.6 3.3 9.1 7.9 7.7 11.6 16.2 7.2 5.1 0.0 8.2 6.7 8.2 8.8 9.6 8.2 19.4 9.7 10.2 9.1 7.2 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657653-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.5;lymphoid tissue: 113.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 105.8;Erythroid cells: 189.3;Extravillous trophoblasts: 115.3;Plasma cells: 112.7;Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.1" "Group enriched" "Detected in many" 6 "NK-cells: 6.7;T-cells: 14.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002784, HPA074922" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB002784: , HPA074922: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 4.5 3.1 4.3 24.2 7.5 88.5 6.7 4.1 6.5 4.8 2.7 22.9 10.5 5.1 1.3 14.8 5.6 3.8 2.2 5.0 4.9 6.5 11.8 4.9 36.1 4.9 5.2 2.1 3.6 1.8 1.6 22.3 4.4 3.1 27.1 4.2 3.9 2.0 0.4 6.2 14.8 12.7 4.8 10.6 8.8 34.3 6.1 113.6 2.1 0.4 44.5 8.4 5.5 10.3 102.7 156.6 320.4 154.9 35.1 57.9 159.9 238.9 141.1 251.7 299.9 132.8 80.1 160.0 91.5 129.9 143.2 45.1 225.3 89.7 216.1 152.3 244.9 273.1 135.8 229.4 8.2 564.8 286.5 51.5 20.7 159.6 49.6 48.4 214.4 334.0 222.0 249.6 321.8 118.1 687.7 311.4 114.7 124.3 114.0 446.8 287.0 191.3 95.6 88.9 106.0 175.7 201.4 91.6 61.1 197.3 63.5 253.5 85.0 289.7 569.5 267.3 474.2 305.9 405.2 367.3 75.2 240.6 339.2 0.0 0.0 1.3 1.1 0.1 0.0 1.1 2.8 2.2 1.8 0.0 0.0 0.6 0.7 6.7 0.1 0.3 14.1 2.9 4.3 7.5 4.1 6.5 5.0 4.9 4.9 5.2 4.4 4.8 6.1 10.3 2.1 0.0 2.3 1.6 15.7 14.4 15.9 13.0 27.9 0.5 7.8 11.7 3.6 2.8 6.7 0.0 0.0 105.8 14.5 15.5 1.9 2.3 34.4 5.6 8.4 12.5 1.2 189.3 0.4 0.8 115.3 28.3 14.3 7.4 7.0 76.2 6.8 4.3 71.4 0.0 0.6 20.9 10.2 15.6 19.4 31.9 6.2 10.7 10.6 1.0 3.9 45.0 5.2 0.5 15.6 1.5 8.9 3.8 112.7 5.0 13.8 36.6 1.0 2.4 13.1 1.3 32.6 180.8 30.7 48.0 7.2 27.0 21.3 10.5 54.9 18.7 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.5;Erythroid cells: 134.3;Extravillous trophoblasts: 103.4;Spermatocytes: 114.1;Spermatogonia: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favorable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 2.3 3.7 6.6 10.4 6.5 28.7 4.5 5.8 13.7 4.1 5.0 13.1 8.7 4.5 4.4 10.6 3.3 2.5 11.3 6.8 7.4 3.5 3.2 3.0 19.0 6.5 6.6 1.0 0.7 4.4 3.0 10.1 6.9 2.1 15.5 2.5 2.7 3.1 17.2 5.3 8.2 9.4 6.0 6.2 4.7 19.3 6.7 47.1 2.9 13.0 18.6 6.3 5.0 6.1 123.3 111.6 167.1 79.8 15.4 27.9 94.2 130.2 72.8 146.0 102.6 79.9 147.1 140.4 50.0 47.0 108.4 98.6 154.1 76.7 131.2 128.1 87.2 85.6 54.0 93.8 6.9 105.2 102.0 9.8 18.1 114.0 47.2 34.3 85.8 157.4 111.0 114.0 116.4 113.3 190.8 135.1 65.4 126.9 57.4 145.0 176.2 122.9 57.1 58.1 131.3 132.8 90.2 112.1 44.8 49.8 117.1 64.6 41.8 65.7 104.6 116.1 159.6 57.8 120.1 182.9 64.5 107.0 139.1 0.0 0.7 1.7 3.3 2.3 2.5 8.5 4.5 3.3 1.7 6.6 6.4 7.1 0.0 1.2 8.9 3.4 10.8 2.4 6.6 6.5 5.8 13.7 6.8 7.4 6.5 6.6 6.9 6.0 6.7 6.1 1.9 0.0 2.2 1.3 13.3 14.3 10.4 29.9 2.8 6.4 6.3 8.6 12.8 0.0 12.1 5.5 0.0 74.5 5.4 10.1 5.9 10.9 24.4 15.7 7.6 5.3 1.2 134.3 8.3 7.5 103.4 11.8 10.7 6.7 8.8 32.2 3.9 2.4 27.7 10.1 6.1 14.4 32.6 1.9 5.4 8.2 3.1 5.8 3.6 1.9 2.6 1.6 0.0 1.0 1.4 10.3 2.9 4.1 32.1 5.2 3.3 12.2 16.2 1.2 6.6 0.8 11.3 114.1 113.1 15.5 10.9 22.4 9.3 12.1 30.5 11.3 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 27.0;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.7;Plasma cells: 21.0;Squamous epithelial cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Cell line enhanced" "Detected in all" "MOLT-4: 450.9;REH: 1004.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 1.0 0.9 2.1 9.6 2.7 27.0 1.7 2.1 2.3 1.6 1.8 2.9 3.7 1.0 0.1 6.5 0.4 0.8 0.5 2.0 2.2 0.6 0.9 1.3 15.8 2.8 2.8 0.3 0.6 0.2 0.2 2.1 2.7 0.6 2.6 0.4 1.5 0.2 1.2 3.4 3.9 1.9 1.9 3.7 3.3 5.2 3.5 67.2 0.3 0.3 10.3 1.6 2.5 4.6 111.3 78.7 116.6 83.4 3.3 13.3 18.5 88.3 42.0 89.9 86.8 94.6 54.9 62.7 21.1 39.4 32.7 54.1 81.2 47.7 63.0 102.7 92.2 54.3 74.3 102.4 1.3 135.1 78.9 6.5 3.5 48.9 12.6 14.1 27.2 97.2 79.3 70.5 54.5 86.7 450.9 82.5 52.5 40.0 84.3 1004.5 259.7 45.4 24.9 80.1 86.0 68.5 69.2 37.7 12.1 18.8 68.2 127.6 34.2 94.6 76.7 124.3 108.3 29.8 33.1 183.5 54.8 129.7 123.3 0.3 0.2 0.1 0.6 0.0 0.0 0.2 0.8 1.0 1.3 0.1 0.2 0.8 0.8 0.5 0.2 4.8 2.3 0.6 2.1 2.7 2.1 2.3 2.0 2.2 2.8 2.8 2.7 1.9 3.5 4.6 0.2 0.0 0.0 1.6 2.1 0.0 0.8 0.0 3.4 2.5 4.4 2.8 4.3 1.5 0.6 0.0 0.0 6.6 6.9 2.6 0.0 2.2 2.9 1.3 1.8 2.2 0.0 49.7 0.4 0.4 7.8 4.7 8.6 2.4 0.0 10.4 0.4 0.7 8.9 3.3 0.4 2.3 0.0 1.9 0.0 1.8 0.6 3.8 0.0 0.0 2.0 0.6 1.0 3.0 1.3 4.2 1.9 0.4 21.0 0.6 1.4 0.2 0.7 0.7 0.0 1.2 6.1 6.1 11.9 15.8 0.0 1.4 3.7 1.5 8.3 1.3 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097597-109110992 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 64.9;Spermatogonia: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 19.8 56.7 32.4 14.7 32.4 16.0 23.1 30.1 34.8 16.6 27.7 28.0 17.1 14.5 12.7 29.7 15.6 10.4 21.1 29.2 34.9 27.5 32.2 9.6 18.0 32.2 31.4 15.7 12.4 33.2 10.9 17.8 34.1 13.6 29.3 6.8 17.7 17.6 43.0 32.7 18.8 14.5 31.6 16.1 17.7 24.3 33.5 22.8 22.2 33.5 27.0 13.5 20.1 30.8 77.1 77.5 72.8 66.6 118.6 33.8 69.5 44.4 30.1 68.6 52.3 61.7 51.6 100.3 65.1 40.2 35.9 47.6 81.4 46.0 66.4 85.6 150.9 98.1 41.1 105.5 17.7 147.6 58.2 30.7 41.6 33.0 18.3 54.6 50.4 117.8 80.9 32.5 47.0 96.2 136.8 173.6 130.0 124.2 117.7 123.9 109.8 85.9 43.4 95.6 103.3 57.4 79.6 67.8 39.5 94.2 126.2 68.2 26.0 59.1 52.7 39.3 62.5 62.6 145.0 190.5 44.8 97.7 73.8 12.9 2.7 5.0 22.4 5.3 31.6 16.0 25.5 25.6 6.8 17.2 16.4 18.4 0.0 16.5 5.5 4.9 25.5 14.4 32.4 32.4 30.1 34.8 29.2 34.9 32.2 31.4 34.1 31.6 33.5 30.8 26.6 0.0 4.8 16.0 9.2 18.0 11.0 13.2 25.0 2.6 21.7 14.1 12.4 7.2 5.0 42.3 4.2 64.9 12.5 14.7 19.6 14.4 3.4 7.6 15.0 17.7 8.4 32.4 7.0 6.2 38.1 12.6 14.3 9.9 7.6 24.8 20.3 20.8 18.3 5.0 6.2 21.4 10.2 3.8 5.4 4.2 14.0 5.5 14.2 6.5 3.8 15.8 7.2 6.6 4.0 5.0 10.3 14.7 16.7 6.8 9.3 20.2 3.2 3.5 6.6 10.2 11.5 21.9 74.6 37.8 20.9 20.4 15.3 25.7 40.4 9.7 USP1 ENSG00000162607 "Ubiquitin specific peptidase 1" O94782 1 62436297-62451804 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 302.7;Spermatogonia: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028387, HPA028440" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028387: AB_2672578, HPA028440: AB_10603000" "unprognostic (1.22e-1)" "unprognostic (5.36e-2)" "unprognostic (1.78e-3)" "unprognostic (4.05e-3)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (6.72e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.33e-3)" "unprognostic (3.99e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-3)" "unprognostic (5.70e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" 13.8 10.6 12.4 21.0 14.7 53.2 23.9 20.2 15.4 16.2 11.8 19.0 17.1 20.7 16.8 17.9 16.7 11.9 12.2 11.5 13.4 14.1 13.5 16.0 32.3 12.8 13.0 26.0 16.0 18.2 10.0 14.4 13.7 16.7 20.7 34.5 14.7 15.9 11.9 19.3 17.2 17.0 14.2 19.4 16.9 51.5 12.9 48.1 20.2 16.0 31.7 13.9 11.9 17.3 85.6 25.5 96.8 53.2 21.3 25.5 57.0 79.7 52.1 93.3 101.2 41.4 39.3 151.3 57.0 43.1 83.6 48.0 80.3 53.0 128.5 79.5 63.5 124.5 82.1 42.7 23.2 132.5 60.9 13.7 33.8 84.1 62.8 25.1 44.9 100.1 92.7 125.3 66.2 38.0 136.9 50.9 88.2 48.5 52.4 131.9 166.3 93.9 34.9 60.1 103.4 58.6 89.3 70.1 86.8 64.2 41.3 79.7 32.1 72.7 80.7 109.3 112.9 52.2 78.1 171.1 49.5 104.0 67.0 22.6 9.9 26.0 12.7 10.5 16.9 15.6 15.3 13.5 12.3 11.2 14.4 12.2 17.4 17.9 14.9 12.4 15.3 10.3 12.4 14.7 20.2 15.4 11.5 13.4 12.8 13.0 13.7 14.2 12.9 17.3 35.8 48.1 31.8 6.2 58.7 62.2 34.7 32.9 75.7 49.6 41.5 46.2 34.9 24.3 34.9 16.5 22.9 43.7 52.4 22.7 19.6 34.1 173.9 37.2 32.3 39.7 8.4 85.2 10.3 34.1 59.2 43.9 15.8 33.2 27.8 41.4 30.0 18.4 31.0 35.3 11.2 33.3 30.5 27.2 38.8 81.1 50.1 34.7 26.6 7.5 56.0 49.5 62.8 10.6 17.2 27.5 12.7 41.0 63.7 56.8 22.7 17.3 41.9 86.6 52.6 59.7 42.0 302.7 206.7 73.8 64.4 33.0 59.7 21.2 39.5 35.8 VRK1 ENSG00000100749 "VRK serine/threonine kinase 1" Q99986 14 96797304-96954846 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.4;testis: 37.1" "Cell type enhanced" "Detected in all" "Spermatocytes: 198.9;Spermatogonia: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 5.9 5.2 5.9 12.8 7.1 50.4 11.5 6.0 7.9 5.2 4.3 10.8 6.5 6.5 6.9 8.9 9.2 4.4 5.2 5.9 5.1 4.9 5.5 4.9 27.1 5.3 5.5 6.0 3.2 5.4 3.1 7.6 5.4 5.0 12.3 4.4 4.3 5.0 4.7 7.4 7.2 6.7 4.8 11.3 6.5 37.1 5.9 35.5 5.9 4.6 27.9 7.7 5.4 7.0 52.4 27.0 78.5 30.2 9.2 14.9 44.8 42.8 34.4 67.1 65.4 36.0 54.7 139.2 22.4 24.3 39.2 56.5 75.5 54.4 90.5 73.4 36.4 90.5 18.7 39.3 10.2 168.5 49.2 8.5 9.7 50.4 32.6 12.8 47.0 104.8 76.6 79.0 56.9 65.5 137.1 76.5 47.8 39.9 59.3 124.5 134.2 48.6 32.3 59.3 53.2 28.0 34.2 36.4 30.8 36.0 39.3 66.6 24.4 27.9 22.8 47.7 37.3 37.7 53.5 124.8 44.7 74.6 34.8 42.7 12.3 26.2 21.5 15.5 29.0 31.3 24.9 26.4 15.7 32.7 27.1 27.3 6.5 45.6 15.2 21.4 34.9 19.4 5.9 7.1 6.0 7.9 5.9 5.1 5.3 5.5 5.4 4.8 5.9 7.0 15.3 3.2 4.6 6.8 30.6 16.8 13.8 23.3 6.2 12.4 9.3 11.3 11.8 12.8 16.7 14.7 8.4 34.8 24.8 6.3 11.7 13.5 21.3 21.1 8.3 12.4 3.0 76.2 42.0 19.4 48.3 11.4 14.8 10.8 28.5 20.0 7.1 3.3 19.2 10.1 36.2 10.4 20.3 11.8 14.9 11.5 5.6 12.0 12.4 19.7 14.2 6.2 27.8 12.1 19.8 10.3 2.2 9.8 25.4 6.1 3.0 11.2 37.6 9.6 19.7 14.3 15.1 198.9 110.9 14.1 13.9 15.1 26.8 9.2 18.1 10.4 WDHD1 "AND-1, CHTF4, CTF4" ENSG00000198554 "WD repeat and HMG-box DNA binding protein 1" O75717 14 54938949-55027105 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 15.5;Spermatocytes: 15.0;Spermatogonia: 19.3" "Cancer enhanced" "Detected in all" "testis cancer: 23.5" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000632, HPA001122" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA000632: , HPA001122: AB_1080589" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-2)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (6.85e-3)" "unprognostic (2.33e-4)" "unprognostic (5.52e-3)" "unprognostic (7.28e-3)" "unprognostic (8.05e-3)" "prognostic unfavorable (9.24e-4)" "unprognostic (5.11e-2)" "unprognostic (2.67e-4)" "unprognostic (8.31e-3)" "unprognostic (1.50e-1)" "unprognostic (3.49e-2)" "unprognostic (2.36e-2)" 1.3 0.8 0.5 3.8 1.0 7.2 2.2 0.9 0.9 1.2 0.1 2.8 1.8 2.1 0.6 2.4 1.6 1.3 0.9 0.7 0.2 1.1 1.2 1.3 5.5 0.2 0.2 1.4 0.9 1.5 0.3 2.8 0.2 1.0 4.0 1.8 0.7 0.8 0.6 2.0 1.7 2.6 0.3 1.7 1.6 5.3 0.4 8.0 0.9 0.8 6.7 1.7 1.1 0.9 39.6 24.7 48.4 21.4 4.6 11.2 28.1 37.5 16.1 29.6 36.0 16.6 25.9 44.9 18.6 10.8 21.4 32.8 72.9 21.5 61.7 30.0 12.7 29.8 23.7 16.2 1.9 56.7 21.8 5.9 3.8 36.6 14.3 7.1 19.6 28.8 37.8 22.0 28.7 21.7 53.5 11.1 38.6 21.1 25.7 49.5 69.7 17.3 8.4 26.0 28.1 19.8 39.8 10.0 12.8 35.1 26.8 11.3 12.8 37.3 43.9 27.5 32.1 6.5 14.4 58.8 17.1 27.4 30.0 1.7 0.3 0.6 0.9 0.2 1.2 1.2 1.0 1.3 0.5 1.8 1.3 1.8 0.4 2.0 0.4 0.7 1.6 0.6 0.5 1.0 0.9 0.9 0.7 0.2 0.2 0.2 0.2 0.3 0.4 0.9 2.3 0.0 2.0 3.9 5.1 3.8 2.2 3.5 3.4 2.9 1.8 1.9 1.7 0.0 4.0 3.7 0.0 8.7 3.6 1.8 0.0 1.8 0.8 1.9 3.1 2.0 0.0 15.5 10.3 1.0 8.4 3.4 2.6 2.5 0.0 12.4 0.7 0.9 4.1 3.3 6.5 2.4 6.1 2.1 1.2 1.1 0.0 2.4 1.8 5.6 1.4 1.4 2.1 4.5 10.1 1.1 0.3 3.0 7.8 0.6 0.5 6.2 3.5 3.1 0.0 2.4 3.0 15.0 19.3 6.1 2.4 2.6 3.6 2.8 5.2 1.7 WDR76 FLJ12973 ENSG00000092470 "WD repeat domain 76" Q9H967 15 43826980-43868412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.1;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.3;Spermatocytes: 23.5;Spermatogonia: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039804, HPA040626" Uncertain Approved "Nucleoli fibrillar center,Nuclear bodies" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Nucleoli fibrillar center" "HPA039804: AB_10795297, HPA040626: AB_10795527" "unprognostic (2.26e-1)" "unprognostic (7.56e-3)" "unprognostic (7.05e-2)" "unprognostic (1.88e-1)" "unprognostic (5.85e-2)" "unprognostic (3.12e-2)" "prognostic unfavorable (6.98e-4)" "prognostic unfavorable (8.02e-5)" "unprognostic (4.24e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.91e-2)" "prognostic unfavorable (1.35e-8)" "unprognostic (7.71e-2)" "unprognostic (9.42e-2)" "unprognostic (4.02e-2)" "unprognostic (3.28e-2)" 2.6 1.2 1.0 8.4 1.1 19.1 3.5 4.8 1.7 3.0 0.8 4.8 3.2 3.3 0.9 4.5 1.7 1.9 1.1 0.7 1.1 1.5 2.2 2.4 19.8 1.3 1.1 2.2 3.1 2.7 1.1 3.9 1.3 1.9 6.0 6.3 2.4 2.0 0.8 4.1 3.3 3.9 1.0 3.6 2.9 5.3 1.3 19.5 2.5 1.3 21.3 2.8 2.8 1.2 35.1 17.5 40.7 31.3 4.5 10.7 11.1 57.3 33.9 61.5 76.8 22.1 17.8 51.4 24.8 26.9 31.0 49.4 42.4 20.5 53.1 80.4 25.2 63.3 52.1 7.3 2.5 65.0 27.0 3.4 3.3 33.8 7.7 8.9 19.9 54.7 48.6 86.9 42.6 12.2 63.4 15.4 14.6 11.0 18.1 66.9 70.1 32.4 11.4 35.5 31.3 30.9 36.1 22.5 7.0 12.6 35.0 31.0 9.1 56.3 26.5 63.5 58.9 42.7 114.6 129.1 40.4 56.7 31.5 0.0 0.6 0.3 3.8 0.5 4.1 1.8 4.6 3.4 1.0 2.2 3.8 2.9 0.0 4.8 0.2 1.2 6.6 2.0 1.0 1.1 4.8 1.7 0.7 1.1 1.3 1.1 1.3 1.0 1.3 1.2 4.1 3.2 1.3 2.6 8.2 7.4 3.2 2.4 4.6 3.7 3.7 2.8 1.2 1.5 2.3 1.8 10.4 12.8 6.2 3.5 1.9 2.9 1.7 1.8 3.9 4.8 0.0 35.3 2.5 4.2 13.0 3.9 4.6 3.3 5.7 12.2 2.9 0.9 8.9 1.7 3.3 3.7 0.0 3.5 5.3 0.9 1.8 3.9 3.6 2.8 3.3 8.0 10.3 0.5 1.9 1.1 3.1 2.2 16.1 1.5 1.4 0.9 0.4 16.2 6.6 5.8 5.7 23.5 35.9 7.4 5.8 3.6 11.6 1.5 9.0 1.8 XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676141 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 14.1;Extravillous trophoblasts: 21.2;Granulosa cells: 20.2;Spermatocytes: 31.3;Spermatogonia: 19.1;Syncytiotrophoblasts: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Vesicles" "HPA065153: AB_2685422" "unprognostic (9.31e-3)" "unprognostic (8.25e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (9.10e-2)" "unprognostic (2.52e-2)" "unprognostic (3.36e-5)" "unprognostic (9.98e-3)" "unprognostic (5.82e-3)" "unprognostic (4.04e-3)" "unprognostic (1.06e-3)" "unprognostic (2.43e-2)" "unprognostic (1.55e-15)" "unprognostic (4.52e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-1)" "unprognostic (1.73e-2)" 0.2 0.2 0.9 2.3 0.6 5.3 1.5 1.6 2.8 0.3 0.0 1.1 1.7 1.1 0.9 1.0 0.5 0.4 1.0 0.6 1.9 0.4 0.4 0.5 2.9 0.6 0.6 1.0 0.0 0.6 0.0 2.1 1.4 0.7 1.7 1.9 0.2 0.4 0.1 1.9 1.5 0.5 1.1 1.0 1.0 3.0 1.0 3.6 0.6 0.0 2.5 0.5 0.1 1.9 16.5 10.4 18.3 15.8 1.1 1.8 15.0 11.8 3.9 8.2 10.3 14.7 12.8 24.8 9.5 3.5 13.7 13.7 12.8 7.1 19.3 8.9 17.3 16.8 15.5 10.0 0.3 27.3 9.3 0.9 1.1 15.6 3.6 2.0 3.8 15.5 34.2 22.8 8.3 12.6 32.4 21.2 21.6 10.8 12.9 22.8 19.3 15.3 3.1 10.3 16.7 18.1 11.7 7.6 5.0 11.3 5.4 8.3 4.2 17.2 6.9 13.3 23.0 8.8 14.5 19.0 11.0 20.9 20.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.6 1.6 2.8 0.6 1.9 0.6 0.6 1.4 1.1 1.0 1.9 0.2 0.0 1.1 1.6 1.9 1.3 1.0 1.0 0.0 4.9 0.8 0.4 2.9 0.0 1.4 1.8 0.0 11.2 0.4 0.9 0.0 1.1 11.7 0.9 1.9 1.1 0.0 14.1 2.3 0.2 21.2 2.5 3.1 1.4 0.0 20.2 1.1 0.2 2.4 0.0 2.0 1.7 2.0 0.6 0.8 4.9 0.9 0.8 0.0 0.0 0.6 1.1 3.1 4.5 2.0 0.5 0.1 1.2 6.1 0.6 0.3 0.3 0.1 2.3 0.0 1.9 1.8 31.3 19.1 2.7 1.4 12.6 2.2 1.2 2.3 1.0 XRCC3 ENSG00000126215 "X-ray repair cross complementing 3" O43542 14 103697609-103715504 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 10.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062422, HPA068953" Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA062422: AB_2684757, HPA068953: AB_2686062" "unprognostic (2.52e-2)" "unprognostic (1.81e-3)" "unprognostic (6.75e-2)" "unprognostic (4.01e-2)" "unprognostic (4.29e-1)" "unprognostic (1.83e-1)" "unprognostic (2.53e-4)" "unprognostic (2.93e-2)" "unprognostic (4.67e-2)" "unprognostic (1.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.53e-2)" "unprognostic (3.52e-7)" "unprognostic (1.27e-1)" "unprognostic (1.57e-1)" "unprognostic (8.84e-2)" "unprognostic (3.72e-2)" 9.8 6.0 8.7 8.7 12.5 31.9 9.3 7.2 10.3 13.7 11.9 11.1 6.9 10.4 1.7 13.9 10.9 6.6 8.3 6.6 5.8 7.9 7.7 12.1 15.4 13.6 9.7 12.7 9.8 1.7 8.6 5.2 9.7 13.4 7.5 4.5 12.7 3.3 12.4 39.0 12.6 2.8 7.7 21.3 9.1 13.8 9.7 10.0 10.5 2.5 11.0 9.6 12.4 14.3 32.4 58.4 31.5 38.5 2.8 7.9 57.0 35.5 11.6 48.9 52.3 32.4 50.3 51.8 29.5 7.5 38.4 50.3 34.6 52.4 29.9 31.3 36.1 50.6 31.6 30.4 4.9 45.3 30.8 6.0 5.2 43.2 26.7 10.4 20.2 51.3 31.8 30.4 25.2 70.7 79.6 35.8 26.4 47.1 42.0 63.7 45.7 19.8 10.5 44.2 31.1 25.7 41.3 21.7 14.3 17.4 34.6 35.0 17.5 25.1 28.9 80.0 38.8 26.2 25.8 63.7 15.6 36.9 38.4 0.7 0.5 0.9 1.0 0.9 1.0 1.1 0.8 0.8 0.5 0.9 0.8 0.5 0.3 0.7 0.7 0.4 0.6 1.3 8.7 12.5 7.2 10.3 6.6 5.8 13.6 9.7 9.7 7.7 9.7 14.3 2.2 0.0 0.0 2.6 2.5 1.5 1.9 2.1 1.8 1.7 3.2 3.6 0.2 2.8 2.5 0.0 2.1 10.2 1.8 6.9 1.9 1.5 0.7 1.9 2.2 2.0 1.2 7.4 2.6 1.8 6.1 1.2 0.5 2.0 0.0 4.7 0.4 0.3 4.4 3.3 1.0 7.4 0.0 0.0 2.0 1.8 0.3 1.5 0.0 1.0 1.5 1.7 2.1 1.5 1.4 1.7 2.6 1.2 4.4 1.6 0.7 0.2 1.7 2.3 0.0 2.6 1.2 3.1 5.8 2.8 1.3 3.1 2.0 4.2 8.3 1.2 ZGRF1 "C4orf21, FLJ11331" ENSG00000138658 "Zinc finger GRF-type containing 1" Q86YA3 4 112539333-112636995 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.0;Microglial cells: 17.8;Oligodendrocytes: 27.5;Spermatocytes: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030704, HPA030706" Uncertain Approved Cytosol NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA030704: AB_2673577, HPA030706: AB_10601784" "unprognostic (8.48e-2)" "unprognostic (6.17e-2)" "unprognostic (9.51e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-3)" "unprognostic (5.83e-3)" "unprognostic (1.45e-1)" "unprognostic (5.89e-4)" "unprognostic (4.74e-2)" "unprognostic (4.30e-2)" "unprognostic (3.72e-3)" "unprognostic (7.60e-10)" "unprognostic (3.45e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-4)" 1.0 0.7 0.9 2.0 1.4 7.8 1.3 2.2 1.5 0.9 0.1 1.1 1.2 1.2 0.3 1.0 0.8 0.5 0.7 0.8 0.7 0.5 0.6 0.9 2.5 1.3 0.9 1.1 0.7 0.3 1.3 1.7 1.3 0.9 1.4 4.3 0.9 0.4 1.2 1.4 1.5 0.9 1.0 1.8 0.9 3.6 1.0 5.2 0.8 0.6 2.9 0.7 0.8 2.1 5.0 3.6 12.1 8.6 0.9 1.6 4.7 8.8 3.7 8.7 7.8 6.9 7.3 13.2 2.5 2.7 3.6 4.0 12.7 4.7 10.0 7.3 3.1 8.3 5.8 2.1 0.4 18.5 5.3 0.8 0.6 11.0 3.0 1.2 3.5 13.6 12.0 14.3 6.0 8.2 25.0 6.7 6.3 5.2 4.2 13.8 18.1 4.5 1.5 4.4 5.6 9.5 3.9 5.3 1.7 8.8 2.5 5.4 4.2 10.9 10.6 5.9 7.1 5.5 10.1 17.0 4.9 6.3 6.3 0.0 0.1 0.3 0.2 0.7 0.1 0.3 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.2 0.1 0.7 0.2 0.1 0.9 1.4 2.2 1.5 0.8 0.7 1.3 0.9 1.3 1.0 1.0 2.1 3.3 0.0 1.3 10.4 5.4 0.0 1.3 0.0 0.6 10.4 2.1 1.7 2.4 0.0 3.7 1.8 8.4 3.5 10.4 2.1 0.0 1.0 2.9 1.8 3.5 1.9 1.2 11.1 18.0 0.5 2.7 2.3 4.6 2.8 2.5 12.2 1.1 0.6 1.8 5.0 14.5 1.8 0.0 1.6 0.0 2.8 0.6 4.1 0.0 17.8 1.3 1.6 6.2 17.6 27.5 0.6 1.4 2.2 10.5 0.8 0.7 0.3 0.7 17.6 0.0 3.1 2.7 22.1 15.6 3.6 0.0 0.8 5.0 2.2 2.5 0.9 ZNF695 SBZF3 ENSG00000197472 "Zinc finger protein 695" Q8IW36 1 246945547-247008093 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 3.2;Extravillous trophoblasts: 4.7;Spermatocytes: 3.5;Spermatogonia: 2.8" "Cancer enhanced" "Detected in many" "testis cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA024743 Uncertain Approved "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "HPA024743: AB_1859419" "unprognostic (8.46e-3)" "unprognostic (6.28e-2)" "unprognostic (1.82e-1)" "unprognostic (2.57e-4)" "unprognostic (4.51e-2)" "unprognostic (1.72e-1)" "unprognostic (1.10e-2)" "unprognostic (1.16e-1)" "unprognostic (5.71e-5)" "unprognostic (7.42e-4)" "unprognostic (2.81e-3)" "unprognostic (2.21e-2)" "unprognostic (1.05e-9)" "unprognostic (2.22e-1)" "unprognostic (2.07e-1)" "unprognostic (2.72e-1)" "unprognostic (3.87e-1)" 0.0 0.0 0.2 0.1 0.2 0.8 0.3 0.1 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.1 0.6 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.2 7.1 0.8 4.2 10.7 0.1 0.1 11.1 2.4 0.1 3.2 4.3 7.3 0.4 5.6 4.4 1.2 2.8 2.2 12.2 0.6 3.7 0.0 4.0 3.8 1.5 4.5 0.0 0.0 1.4 0.2 0.0 3.6 2.9 0.9 1.3 7.3 5.2 0.0 3.4 2.7 8.2 4.1 7.8 6.8 4.3 4.5 9.7 0.0 0.8 3.8 3.7 6.5 3.4 2.8 1.2 4.0 3.0 5.2 0.6 0.5 6.0 3.2 0.0 0.7 2.2 0.1 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.6 0.0 0.8 1.1 0.5 0.0 0.0 0.0 0.0 3.2 0.0 0.4 0.0 0.3 0.9 0.9 0.5 0.3 0.0 2.1 0.0 0.0 4.7 0.4 1.5 1.4 0.0 2.0 0.4 0.2 1.4 0.0 0.0 2.1 0.0 0.8 0.3 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.5 3.5 2.8 2.0 0.1 1.1 0.0 0.3 1.7 0.2 ZNF726 ZNF92P3 ENSG00000213967 "Zinc finger protein 726" A6NNF4 19 23914876-23945159 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 8.2;NK-cell: 3.1" "Group enriched" "Detected in many" 4 "granulocytes: 8.2;NK-cells: 3.1" "Cell line enhanced" "Detected in many" "MOLT-4: 29.6" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (5.40e-2)" "unprognostic (2.27e-1)" "unprognostic (4.41e-3)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "unprognostic (4.97e-2)" "unprognostic (1.80e-1)" "unprognostic (2.91e-2)" "unprognostic (8.26e-4)" "unprognostic (5.65e-4)" "unprognostic (2.14e-2)" "unprognostic (9.87e-3)" "unprognostic (2.90e-2)" "unprognostic (4.25e-2)" "unprognostic (1.64e-1)" "unprognostic (4.97e-2)" "unprognostic (3.20e-3)" 1.2 1.3 2.5 1.8 1.8 5.8 4.2 3.8 2.3 2.9 0.9 1.9 1.2 2.2 5.1 2.4 1.7 2.1 0.7 2.0 2.6 2.8 2.2 1.6 4.2 1.9 2.2 1.4 0.7 2.1 0.6 3.4 2.2 2.5 3.9 3.2 1.3 2.0 1.6 4.8 1.3 1.0 1.6 2.5 3.0 2.9 3.4 6.1 2.2 1.0 3.4 1.7 2.8 2.5 1.1 1.9 16.3 9.0 1.1 1.1 0.8 4.0 1.4 8.7 8.3 1.4 5.3 0.1 7.5 1.7 6.3 1.2 15.2 0.2 11.8 11.3 8.0 6.6 1.5 0.4 0.6 0.1 3.8 1.2 0.9 5.2 0.3 1.0 0.0 9.5 5.2 0.1 3.3 5.6 29.6 19.8 9.8 0.1 8.4 21.6 12.1 4.8 3.0 6.6 5.4 9.1 0.0 0.1 4.1 7.9 10.5 1.3 1.1 3.1 2.3 13.5 8.5 0.1 9.2 13.1 0.1 2.4 4.5 8.2 0.4 0.2 0.4 0.5 0.2 0.7 1.0 1.0 0.4 1.0 1.0 1.2 0.8 3.1 0.3 1.1 1.2 0.6 2.5 1.8 3.8 2.3 2.0 2.6 1.9 2.2 2.2 1.6 3.4 2.5 0.6 3.2 0.0 2.9 2.4 0.9 1.6 0.2 0.6 3.8 2.4 1.3 4.5 1.5 1.1 3.7 0.0 7.2 2.9 1.5 1.9 1.4 0.1 1.8 2.4 2.2 0.0 9.0 1.0 0.2 6.7 1.8 0.0 2.6 3.8 5.3 1.4 2.0 2.2 5.0 2.4 0.7 2.0 1.9 2.0 0.3 0.3 1.2 0.0 0.0 0.8 0.6 3.1 5.0 2.9 0.6 0.3 1.9 1.4 0.9 0.1 0.5 2.5 1.2 0.0 1.7 1.7 2.3 6.0 2.0 1.7 4.1 2.4 1.8 0.5 1.5 ZNF850 ZNF850P ENSG00000267041 "Zinc finger protein 850" A8MQ14 19 36714383-36772825 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.1" "Cell type enhanced" "Detected in many" "Early spermatids: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 15.2;NTERA-2: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029299 Uncertain Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA029299: AB_2672987" "unprognostic (1.35e-2)" "unprognostic (5.54e-2)" "unprognostic (3.85e-2)" "unprognostic (1.38e-3)" "unprognostic (7.78e-2)" "unprognostic (6.63e-2)" "unprognostic (1.65e-3)" "unprognostic (1.68e-1)" "unprognostic (1.21e-2)" "unprognostic (1.25e-1)" "unprognostic (3.00e-2)" "unprognostic (5.56e-2)" "unprognostic (4.11e-3)" "unprognostic (1.77e-1)" "unprognostic (7.49e-2)" "unprognostic (4.49e-2)" "unprognostic (7.37e-3)" 0.8 0.6 0.7 1.0 0.6 5.1 0.9 2.4 1.0 0.7 0.9 0.7 0.6 0.7 0.3 1.0 0.7 0.8 1.6 1.5 0.7 0.6 0.9 0.7 1.5 0.9 0.7 1.2 0.6 1.0 0.5 3.1 0.8 0.9 1.0 1.0 0.7 0.7 0.4 1.2 0.6 0.8 0.3 1.1 0.7 2.6 0.7 0.7 0.7 0.5 0.8 0.5 0.5 1.4 0.3 1.7 3.7 6.0 0.8 0.2 7.0 2.2 1.3 1.5 1.8 1.3 0.4 1.2 5.1 0.4 7.6 1.1 2.6 0.5 2.7 0.8 2.3 15.2 0.3 1.2 1.0 1.8 8.6 1.0 0.1 2.3 0.0 0.5 1.3 1.8 4.4 0.8 3.6 0.8 2.7 1.7 11.9 0.6 1.0 1.7 7.8 1.1 0.7 7.5 2.4 3.8 3.5 0.2 0.5 5.0 1.5 3.3 2.9 3.6 5.9 2.1 3.7 1.4 2.7 3.2 0.0 0.9 5.6 1.8 1.2 0.9 1.3 1.3 1.7 2.7 1.6 1.1 1.1 1.7 1.8 2.0 1.9 1.3 1.5 1.2 1.2 2.2 0.7 0.6 2.4 1.0 1.5 0.7 0.9 0.7 0.8 0.3 0.7 1.4 2.4 0.0 0.0 0.7 1.7 2.2 1.3 0.5 1.8 1.1 1.9 1.5 5.1 1.5 0.2 3.7 0.0 4.4 1.3 0.3 0.0 1.0 8.0 1.6 1.5 2.9 0.0 5.7 1.3 0.7 5.4 3.0 0.5 2.4 0.0 3.6 7.1 2.1 1.3 5.0 1.0 3.5 2.0 2.2 2.1 3.3 1.2 0.8 3.6 1.9 0.5 1.2 2.1 3.0 3.7 0.6 0.4 0.4 0.7 0.8 0.1 0.7 0.2 0.5 0.0 2.5 1.6 5.9 5.7 1.1 3.4 2.9 1.1 1.7 0.8 0.9 ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.6;lymphoid tissue: 43.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 133.0;Extravillous trophoblasts: 108.6;Late spermatids: 208.8;Spermatocytes: 121.0;Spermatogonia: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: AB_10600224, HPA022264: AB_10600995" "unprognostic (5.59e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-2)" "unprognostic (9.38e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.77e-8)" "unprognostic (6.36e-3)" "unprognostic (5.88e-2)" "unprognostic (1.45e-2)" "unprognostic (1.58e-3)" "unprognostic (1.86e-2)" "prognostic unfavorable (3.72e-12)" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (5.47e-2)" "unprognostic (3.46e-1)" 2.6 2.5 1.2 15.7 1.3 41.6 6.5 1.1 1.8 3.9 1.0 18.8 13.7 3.2 1.7 12.4 2.8 2.4 1.5 1.5 1.2 4.4 4.8 2.9 26.5 1.2 1.3 1.5 2.4 5.4 0.8 10.8 1.2 2.5 22.4 0.5 3.3 1.4 0.3 10.8 14.8 6.8 1.2 5.0 12.5 26.1 1.6 43.5 3.9 0.7 33.0 5.0 4.3 1.4 199.8 154.8 107.9 120.9 7.5 10.8 88.1 143.1 108.0 169.6 153.4 275.4 116.1 102.0 53.2 49.6 79.1 99.9 153.2 108.3 156.7 259.9 80.2 101.6 120.8 129.4 0.7 169.6 131.0 5.1 6.8 157.7 64.9 20.8 86.8 134.2 140.2 121.4 151.1 160.1 150.7 108.3 77.0 135.9 188.7 151.7 209.5 54.0 53.5 87.5 99.8 61.2 135.2 304.2 35.3 62.2 197.3 163.4 47.4 73.6 189.4 76.9 223.2 105.8 55.3 176.0 103.8 210.0 94.7 0.0 0.8 0.7 2.4 3.0 0.3 1.6 5.3 3.6 1.4 0.3 6.3 3.6 0.0 3.5 2.3 1.1 17.0 3.1 1.2 1.3 1.1 1.8 1.5 1.2 1.2 1.3 1.2 1.2 1.6 1.4 0.9 3.2 1.7 0.3 11.1 18.4 6.0 20.2 4.6 2.0 9.4 5.5 1.4 2.8 7.3 5.5 0.0 73.7 3.3 17.9 0.0 9.7 74.0 7.0 4.3 5.7 0.0 133.0 1.3 13.3 108.6 10.3 16.8 8.0 0.0 27.6 7.9 3.5 49.4 0.0 0.3 22.8 14.2 8.5 8.8 208.8 5.0 9.2 7.2 0.0 2.6 1.3 0.0 0.0 0.6 8.6 16.4 2.6 42.4 1.9 8.7 6.0 2.5 0.9 0.0 1.4 10.6 121.0 100.3 24.5 8.2 23.1 7.9 6.5 39.4 8.4