Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADACL2 MGC72001 ENSG00000197953 "Arylacetamide deacetylase like 2" Q6P093 3 151733916-151761339 "Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "skin 1: 35.6" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 30.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.20e-2)" "unprognostic (3.10e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (3.00e-1)" "unprognostic (2.91e-4)" 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 35.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 30.7 0.1 0.1 0.0 0.0 0.0 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABHD13 "bA153I24.2, BEM46L1, C13orf6, FLJ14906" ENSG00000139826 "Abhydrolase domain containing 13" Q7L211 13 108218392-108234243 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032143, HPA032144" Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" Cytosol "HPA032143: AB_2674178, HPA032144: AB_10602304" "unprognostic (2.69e-1)" "unprognostic (2.81e-1)" "unprognostic (1.36e-2)" "unprognostic (2.91e-2)" "unprognostic (8.36e-2)" "unprognostic (1.48e-2)" "unprognostic (1.99e-1)" "unprognostic (2.63e-1)" "unprognostic (8.75e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-1)" "unprognostic (6.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.73e-2)" "unprognostic (1.61e-1)" "unprognostic (1.14e-1)" "unprognostic (5.62e-2)" 7.0 5.3 3.7 7.0 4.0 16.3 7.3 5.9 5.3 6.2 7.0 6.5 7.0 6.3 10.2 5.6 4.3 6.4 4.3 4.1 3.2 6.1 10.4 6.9 8.3 3.3 3.3 5.2 4.7 5.7 3.8 8.4 3.2 6.2 7.3 6.4 4.6 5.6 4.2 4.3 7.4 6.8 3.2 7.8 6.8 3.8 3.4 9.3 7.6 6.4 7.1 7.5 4.3 3.9 9.8 4.0 10.5 5.9 8.0 9.5 5.1 9.5 9.5 8.2 9.7 6.2 9.1 8.2 9.7 7.4 8.1 8.8 7.9 11.0 13.0 11.1 6.9 10.1 5.7 6.1 8.0 21.1 12.0 9.8 10.3 6.4 8.3 7.7 9.8 11.2 5.5 4.5 8.5 4.1 10.3 8.8 5.0 14.5 4.7 8.7 7.5 4.8 11.5 8.7 7.9 9.9 5.0 8.3 10.6 9.3 7.7 19.3 10.2 5.8 6.0 6.8 6.5 8.8 7.4 9.0 13.7 13.0 10.7 7.7 8.2 16.0 5.9 7.6 8.8 6.8 8.0 7.2 7.2 6.0 7.6 6.3 9.0 9.5 7.2 5.3 8.4 8.6 3.7 4.0 5.9 5.3 4.1 3.2 3.3 3.3 3.2 3.2 3.4 3.9 17.6 22.4 16.6 8.1 24.5 44.4 21.4 33.3 15.9 12.8 16.8 10.8 7.2 27.1 22.2 11.0 0.0 20.9 23.7 14.7 9.8 19.1 24.8 12.3 13.4 18.2 30.5 16.2 21.4 21.0 15.4 19.9 19.9 14.4 14.0 9.5 19.6 29.5 19.5 18.5 17.4 11.6 44.7 21.5 40.1 18.2 15.5 24.6 26.6 15.0 25.8 12.6 19.6 16.1 15.2 20.8 14.3 17.3 10.2 20.7 16.4 11.5 18.4 12.2 19.7 15.1 18.2 22.9 12.3 21.1 51.1 21.3 28.4 12.5 12.1 26.3 C1orf52 "FLJ44982, gm117" ENSG00000162642 "Chromosome 1 open reading frame 52" Q8N6N3 1 85249953-85259672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036072, HPA061790" Approved Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA036072: AB_10602696, HPA061790: AB_2684610" "unprognostic (1.59e-1)" "unprognostic (2.30e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (5.37e-5)" "unprognostic (6.67e-3)" "unprognostic (2.95e-2)" "unprognostic (3.73e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (4.93e-4)" "prognostic unfavorable (1.17e-7)" "unprognostic (8.01e-2)" "unprognostic (2.54e-1)" "unprognostic (4.14e-1)" "unprognostic (2.05e-2)" 15.1 11.0 11.7 10.3 15.0 23.0 13.4 9.4 16.7 13.8 5.5 14.2 6.3 11.7 7.5 13.1 12.5 6.7 14.8 17.7 10.6 12.2 15.2 14.0 15.2 10.7 11.8 13.0 13.0 5.3 13.3 12.2 11.0 12.5 6.5 10.7 9.2 7.3 16.3 12.2 11.4 5.2 8.8 14.8 12.0 15.9 11.5 9.7 11.5 9.9 8.5 12.9 13.1 16.2 25.6 12.1 17.3 15.6 18.6 14.4 21.4 20.4 10.6 26.2 23.2 17.2 13.1 20.0 17.2 22.5 14.7 16.1 42.4 12.3 13.0 26.1 25.4 32.2 19.5 15.5 11.3 28.0 14.2 9.4 17.8 24.1 11.9 13.0 9.7 35.2 35.9 23.6 13.0 7.3 27.3 13.8 63.7 12.0 9.8 28.3 18.5 10.8 14.2 7.0 7.3 16.4 5.0 16.3 20.7 17.4 8.8 57.7 16.6 10.6 19.5 27.2 32.8 22.6 46.2 28.3 8.9 21.7 12.9 17.6 18.4 30.0 19.5 28.6 21.1 35.5 18.1 17.2 24.7 19.6 27.5 26.4 30.1 19.7 24.0 26.8 17.3 22.3 11.7 15.0 9.4 16.7 17.7 10.6 10.7 11.8 11.0 8.8 11.5 16.2 46.7 44.8 34.3 31.3 48.4 145.4 55.0 60.0 56.9 23.5 51.9 50.3 24.3 21.5 46.0 16.5 22.9 61.3 56.3 23.4 19.6 33.3 69.0 36.3 36.1 40.7 38.8 29.0 37.4 27.5 61.1 46.9 23.4 40.9 51.3 25.4 29.6 16.6 37.1 15.2 21.7 25.1 77.3 28.9 81.6 16.8 36.7 32.5 32.0 21.5 25.4 30.8 38.1 23.1 58.6 37.9 24.6 24.5 42.7 53.0 25.9 19.7 34.0 27.1 39.5 27.7 45.6 92.5 67.3 63.9 128.9 67.9 53.4 27.5 24.7 71.5 C1orf68 "LEP7, XP32" ENSG00000198854 "Chromosome 1 open reading frame 68" Q5T750 1 152719522-152720470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 678.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 78.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 2.4;melanoma: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HaCaT: 1.8" "Not detected" "Not detected" HPA057942 Approved "Plasma membrane,Cytosol" NA NA 220000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" Cytosol "HPA057942: " "unprognostic (1.73e-1)" "unprognostic (7.46e-2)" "unprognostic (9.34e-2)" 0.4 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 678.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.8 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 78.3 0.0 0.1 0.0 0.0 0.0 CALML5 CLSP ENSG00000178372 "Calmodulin like 5" Q9NZT1 10 5498697-5499570 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 3060.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 172.1;Breast myoepithelial cells: 156.1;Suprabasal keratinocytes: 390.7" "Group enriched" "Detected in many" 6 "breast cancer: 97.6;cervical cancer: 189.1;head and neck cancer: 206.0;melanoma: 222.1;urothelial cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "A-431: 400.3" "Not detected" "Not detected" HPA040725 Enhanced Approved "Plasma membrane,Cytosol" NA NA 48000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA040725: AB_10793863" "unprognostic (7.68e-3)" "unprognostic (5.06e-3)" "unprognostic (5.64e-2)" "prognostic favorable (2.59e-5)" "unprognostic (4.82e-2)" "unprognostic (2.67e-1)" "unprognostic (1.37e-1)" "unprognostic (8.27e-2)" "unprognostic (1.14e-1)" "unprognostic (2.79e-1)" "unprognostic (1.71e-1)" "unprognostic (4.99e-2)" 3.9 0.5 0.0 0.0 0.0 0.1 41.2 0.0 0.0 94.0 0.0 0.8 0.0 0.3 0.7 67.5 0.1 0.0 1.3 0.0 0.0 0.3 1.7 0.8 0.0 0.0 0.0 0.4 1.1 0.0 0.5 0.0 0.0 0.5 0.0 0.0 554.0 0.0 11.7 3060.6 0.6 0.0 0.0 0.4 0.8 1.0 0.0 9.2 0.6 0.0 13.4 0.1 306.6 0.0 400.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.8 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 27.3 0.3 2.2 0.0 0.0 172.1 156.1 0.2 0.0 1.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 11.1 0.0 0.0 0.4 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 1.3 0.2 0.3 6.8 390.7 0.0 1.2 0.0 0.0 3.3 CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skin 1: 486.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 96.0" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "hTCEpi: 49.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3600000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: AB_2672101" "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" 0.6 0.0 0.1 0.0 0.4 0.4 7.8 0.4 0.2 3.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.8 0.0 0.1 1.1 4.2 1.4 486.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.0 0.0 0.0 0.0 0.0 19.9 1.0 1.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.2 0.1 0.3 0.1 0.3 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 19.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 96.0 0.7 0.1 0.0 0.0 0.8 CBWD2 ENSG00000136682 "COBW domain containing 2" Q8IUF1 2 113437691-113496204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 110.3;Suprabasal keratinocytes: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (4.67e-2)" "unprognostic (2.17e-1)" "unprognostic (4.14e-1)" "prognostic unfavorable (3.22e-5)" "unprognostic (7.69e-2)" "unprognostic (2.17e-1)" "unprognostic (2.16e-3)" "unprognostic (1.31e-3)" "unprognostic (3.69e-2)" "unprognostic (1.72e-2)" "unprognostic (5.85e-2)" "unprognostic (1.39e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-1)" "unprognostic (4.90e-2)" "unprognostic (3.21e-1)" "unprognostic (7.57e-3)" 4.7 8.3 5.8 5.3 6.3 1.5 7.0 7.0 7.2 8.2 7.1 8.4 2.2 7.0 7.1 9.4 4.5 4.5 15.9 6.3 6.7 13.8 10.5 4.0 3.2 6.0 6.2 5.4 5.6 16.2 8.8 5.9 6.1 6.4 5.9 6.3 8.1 7.4 26.0 4.3 4.6 8.1 5.5 4.9 6.5 2.0 6.0 6.8 9.6 23.9 4.6 8.7 5.4 6.4 16.1 9.7 9.8 11.2 25.7 11.8 19.2 11.9 7.4 9.1 12.0 16.0 9.6 20.7 36.2 12.8 42.1 13.2 10.8 13.2 12.0 7.5 28.9 17.4 16.8 29.8 8.6 8.1 7.8 11.1 8.1 13.4 8.1 17.7 17.1 11.1 10.1 22.2 13.4 17.1 23.3 24.2 11.9 30.2 20.7 10.9 26.6 54.6 24.6 25.1 28.0 8.0 31.4 4.6 5.1 33.7 14.5 21.6 20.8 7.7 10.7 4.8 11.9 8.5 38.2 10.5 12.8 44.5 19.3 15.6 67.7 35.6 12.1 68.4 13.2 17.9 18.2 14.3 65.3 22.7 15.3 14.1 18.5 20.2 56.2 16.2 27.0 52.9 5.8 6.3 7.0 7.2 6.3 6.7 6.0 6.2 6.1 5.5 6.0 6.4 5.6 9.6 20.5 11.8 32.5 110.3 12.8 24.5 62.6 10.5 15.9 14.9 49.6 18.6 20.0 14.7 16.7 17.6 7.1 7.2 39.2 29.6 18.6 10.3 7.1 11.9 2.4 23.7 27.3 14.3 13.2 16.4 23.0 11.1 15.8 9.5 6.1 11.4 9.0 13.5 25.8 11.4 16.2 9.4 62.5 18.4 10.8 20.0 26.6 21.5 53.8 10.9 2.1 15.6 24.9 12.7 14.1 17.3 78.7 14.9 13.7 33.9 26.4 14.0 0.0 9.6 17.1 21.7 13.6 61.0 120.0 25.9 18.4 11.6 17.3 12.2 CBWD6 CBWD7 ENSG00000215126 "COBW domain containing 6" Q4V339 9 41131306-41199261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.4;Excitatory neurons: 24.9;Inhibitory neurons: 20.2;Langerhans cells: 30.0;Oligodendrocyte precursor cells: 18.6;Suprabasal keratinocytes: 42.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 17.3;PC-3: 26.8;TIME: 16.6" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (9.48e-2)" "unprognostic (6.02e-2)" "unprognostic (1.62e-2)" "unprognostic (1.91e-2)" "unprognostic (1.30e-2)" "unprognostic (6.28e-2)" "unprognostic (5.92e-2)" "unprognostic (3.71e-2)" "unprognostic (2.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.24e-2)" "unprognostic (1.09e-1)" "unprognostic (2.28e-4)" "unprognostic (5.65e-2)" "unprognostic (1.65e-1)" "unprognostic (1.01e-2)" "unprognostic (9.94e-4)" 2.0 5.3 1.8 0.7 1.8 2.2 2.1 1.8 3.4 1.0 2.5 1.9 1.1 1.2 0.2 2.9 0.9 1.5 3.4 1.8 2.1 3.4 7.2 2.0 0.3 1.9 1.9 1.6 3.4 0.1 2.7 0.2 2.2 1.7 0.1 0.9 2.5 1.9 3.6 1.5 1.9 0.3 1.9 2.1 2.2 1.9 2.0 0.1 2.2 0.0 0.5 1.1 1.9 1.8 2.0 0.5 0.9 0.2 0.9 2.4 1.6 11.0 12.4 12.6 0.0 4.3 1.2 2.7 0.5 9.0 0.5 1.8 15.9 0.3 0.4 2.8 10.6 0.7 6.4 2.9 0.1 3.4 1.0 0.2 1.5 8.4 10.1 0.9 9.7 0.8 1.4 1.5 17.3 1.8 5.1 0.7 2.3 4.5 26.8 1.2 10.8 3.6 11.5 0.5 0.7 1.2 2.7 0.8 1.1 2.2 0.9 1.5 16.6 0.2 1.0 0.3 1.2 4.9 0.8 13.5 1.5 1.0 1.2 1.6 4.1 1.7 0.6 5.0 0.9 3.5 2.9 2.3 2.3 1.2 1.8 2.2 0.6 0.4 7.0 2.7 1.3 2.4 1.8 1.8 1.8 3.4 1.8 2.1 1.9 1.9 2.2 1.9 2.0 1.8 2.0 3.2 8.9 5.2 1.3 39.4 0.0 11.0 0.0 0.0 5.1 2.7 0.0 0.0 7.5 5.5 0.0 5.2 1.4 0.0 3.9 4.3 0.0 1.5 0.9 1.4 0.0 0.0 24.9 4.9 5.2 1.4 0.0 1.4 8.8 2.2 0.0 0.0 3.0 0.0 20.2 0.0 8.2 0.0 30.0 0.0 0.0 1.4 14.2 5.6 1.6 0.0 0.0 18.6 8.1 4.4 0.0 0.0 1.4 0.0 0.0 8.8 7.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 42.9 6.3 2.8 1.4 0.0 0.0 CCL27 "ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine" ENSG00000213927 "C-C motif chemokine ligand 27" Q9Y4X3 9 34661880-34664048 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 485.0" "Group enriched" "Detected in some" 26 "Basal keratinocytes: 704.5;Suprabasal keratinocytes: 1004.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.9" "Not detected" "Not detected" HPA073848 Enhanced "Secreted to blood" NA NA 436000 1800000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 61: Skin - Cornification" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "HPA073848: AB_2732243" 0.3 0.0 1.8 0.1 1.8 1.6 27.6 3.5 4.8 0.6 1.5 0.1 0.3 0.7 3.1 0.7 0.2 0.7 0.6 1.8 1.8 0.0 0.3 0.1 0.3 2.0 1.8 0.9 0.1 0.1 0.1 0.3 1.9 0.2 0.2 0.9 0.3 0.1 1.4 485.0 0.1 0.2 1.9 0.1 0.1 1.3 1.8 4.6 1.2 0.3 0.2 0.1 0.6 2.2 0.0 0.0 0.3 1.9 0.8 0.3 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 1.1 0.7 0.0 0.0 1.1 0.4 0.3 0.0 0.0 1.4 0.8 0.2 0.0 0.3 0.0 0.5 0.2 1.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 1.3 0.7 0.0 0.0 0.9 0.8 0.7 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 1.8 3.5 4.8 1.8 1.8 2.0 1.8 1.9 1.9 1.8 2.2 0.1 0.0 0.0 0.3 0.0 704.5 0.3 0.3 0.0 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 7.8 0.0 0.3 1.7 0.0 0.0 0.2 0.2 0.8 2.3 0.0 0.1 0.0 0.1 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.0 28.4 9.6 0.3 0.0 32.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.2 0.0 0.2 1.6 4.5 1.5 0.0 1004.0 1.9 0.8 0.0 0.2 0.1 CENPP "CENP-P, RP11-19J3.3" ENSG00000188312 "Centromere protein P" Q6IPU0 9 92325953-92620529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 21.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.3;Excitatory neurons: 73.4;Inhibitory neurons: 70.5;Microglial cells: 94.6;Oligodendrocytes: 74.5;Suprabasal keratinocytes: 100.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021787, HPA058945" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Nucleoli "HPA021787: AB_1846524, HPA058945: AB_2683860" "unprognostic (5.48e-2)" "prognostic favorable (3.91e-4)" "unprognostic (1.20e-1)" "unprognostic (2.43e-3)" "unprognostic (2.64e-2)" "prognostic favorable (3.65e-4)" "unprognostic (4.88e-5)" "unprognostic (8.06e-2)" "unprognostic (3.51e-3)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (6.68e-3)" "unprognostic (9.20e-8)" "unprognostic (1.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.11e-1)" "unprognostic (2.04e-1)" 3.4 3.0 1.7 3.5 2.1 12.3 3.0 5.6 2.1 3.8 0.8 2.4 2.8 2.9 0.7 4.4 2.0 2.8 2.8 2.0 1.5 2.0 1.8 1.9 5.6 1.7 1.4 2.2 2.1 2.4 1.8 3.1 2.0 2.3 2.7 2.4 2.2 1.5 9.0 21.4 1.9 3.0 1.0 2.7 1.8 4.5 1.8 7.1 1.4 4.5 6.4 2.3 4.0 1.8 14.2 8.7 12.0 8.8 4.9 5.3 11.7 14.6 8.2 17.9 14.3 4.0 7.9 18.5 6.7 4.7 16.5 16.8 11.6 8.0 16.6 26.3 15.1 18.6 7.2 5.7 2.6 38.2 17.0 5.8 4.5 17.3 11.1 2.5 9.2 17.5 20.8 25.2 13.8 9.0 53.4 11.6 10.1 26.6 17.9 17.9 20.3 20.0 2.7 14.1 27.8 9.6 16.8 10.5 5.4 8.7 5.6 11.4 4.4 17.4 8.7 26.6 21.2 16.7 21.6 23.9 19.5 18.9 16.1 1.8 1.8 2.6 2.6 6.4 4.7 4.6 3.0 2.3 2.3 3.6 2.7 2.7 0.5 3.5 3.3 3.0 3.5 2.0 1.7 2.1 5.6 2.1 2.0 1.5 1.7 1.4 2.0 1.0 1.8 1.8 3.7 0.0 0.5 17.3 4.5 63.3 4.0 4.5 5.2 6.2 4.0 2.7 2.1 2.8 1.3 0.0 8.4 6.2 3.3 1.6 1.9 1.7 17.5 2.4 4.2 4.4 1.2 11.2 73.4 2.3 9.2 5.8 5.6 2.3 0.0 6.4 2.5 0.9 17.1 1.7 70.5 1.5 0.0 2.1 11.7 4.7 4.4 4.0 14.2 94.6 0.5 2.8 1.0 38.2 74.5 1.1 0.4 4.9 11.9 2.8 0.4 1.8 0.3 7.8 6.6 20.8 9.2 30.2 16.2 9.8 100.9 3.8 3.6 4.4 2.6 2.7 CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 348.7;Suprabasal keratinocytes: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 365.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" 20.8 15.9 9.1 12.9 8.5 27.1 18.1 12.6 9.6 16.0 12.1 12.4 12.3 12.3 10.3 27.4 12.1 20.5 15.1 8.6 9.2 14.2 20.3 19.7 14.7 8.6 8.5 13.0 9.9 6.5 9.3 13.5 9.0 12.9 8.9 5.9 15.2 5.7 9.8 27.5 13.2 10.5 7.8 17.3 12.9 39.6 9.2 21.9 11.9 6.6 13.3 15.1 18.1 9.7 25.4 4.6 12.8 11.9 21.5 16.8 13.1 34.6 36.1 20.1 20.3 18.1 22.0 21.4 29.5 22.0 17.2 7.7 17.9 25.1 22.0 11.9 9.5 11.7 4.2 13.6 65.1 19.2 23.4 22.6 19.8 30.3 45.3 38.3 30.0 22.2 13.0 15.4 40.6 7.1 22.3 30.7 8.7 11.2 16.9 14.3 7.3 8.4 23.3 8.1 19.7 18.3 8.3 12.2 26.6 18.3 6.1 26.8 51.3 25.2 19.9 36.6 21.4 18.4 9.5 17.2 18.7 18.7 18.7 365.5 79.3 171.5 60.1 64.7 57.7 41.3 60.0 68.6 55.9 40.1 54.6 59.6 325.0 74.2 68.3 47.0 81.5 77.9 9.1 8.5 12.6 9.6 8.6 9.2 8.6 8.5 9.0 7.8 9.2 9.7 58.1 6.4 7.3 35.6 42.5 348.7 95.5 61.0 68.3 8.1 61.6 33.5 4.1 15.7 25.9 7.3 8.4 27.8 57.8 27.2 17.6 42.8 55.4 64.1 58.0 64.3 25.8 72.6 39.7 28.0 38.7 80.8 32.6 34.2 36.3 36.8 38.6 23.9 24.7 13.5 40.2 21.9 40.7 36.4 144.2 13.4 17.1 50.3 67.6 49.6 32.6 9.0 28.8 74.4 23.2 61.8 42.1 24.5 40.2 85.1 41.9 29.2 56.0 7.2 19.7 53.9 45.1 163.5 89.9 97.4 373.8 47.7 65.8 39.8 21.0 135.9 CLEC2A "INPE5792, KACL, PILAR, UNQ5792" ENSG00000188393 "C-type lectin domain family 2 member A" Q6UVW9 12 9898673-9932370 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 57.6" "Group enriched" "Detected in some" 11 "Basal keratinocytes: 18.7;Suprabasal keratinocytes: 37.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 22.0;U-937: 54.6" "HPA048530, HPA072407" Approved Uncertain "Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA048530: AB_2680429, HPA072407: AB_2686518" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 3.5 2.1 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 57.6 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 54.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.1 0.3 0.2 0.3 0.5 0.3 0.5 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 37.1 0.0 0.1 0.0 0.0 0.1 CRKL ENSG00000099942 "CRK like proto-oncogene, adaptor protein" P46109 22 20917407-20953747 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 344.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000532, HPA001100" Uncertain Enhanced Nucleoplasm,Cytosol NA NA 2100000 "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Cytosol "HPA000532: AB_2666019, HPA001100: AB_1078569" "unprognostic (5.54e-2)" "unprognostic (2.66e-1)" "unprognostic (5.87e-2)" "unprognostic (2.40e-2)" "unprognostic (3.06e-2)" "unprognostic (1.59e-1)" "unprognostic (1.92e-2)" "unprognostic (6.51e-2)" "unprognostic (2.35e-2)" "unprognostic (4.60e-1)" "unprognostic (2.71e-1)" "unprognostic (5.99e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (8.40e-2)" "unprognostic (1.43e-1)" "unprognostic (9.52e-2)" "unprognostic (1.61e-2)" 16.7 14.8 34.5 18.4 34.9 53.7 16.3 34.6 35.7 17.5 26.0 18.4 22.0 19.4 13.0 26.6 20.4 14.3 25.1 33.7 33.5 17.1 27.3 20.7 25.5 36.8 37.0 27.4 23.5 19.1 16.1 25.9 34.0 16.5 19.6 22.4 14.8 19.0 54.3 24.9 19.7 19.5 38.8 22.4 14.7 13.3 38.9 33.3 14.8 43.0 27.6 18.9 18.4 36.0 43.9 25.8 56.7 44.8 37.5 23.9 61.0 29.0 35.5 43.7 49.1 42.8 19.2 56.1 22.9 30.8 30.0 54.8 67.2 46.3 51.7 47.7 65.5 77.7 28.6 47.3 37.4 83.5 38.0 24.3 60.3 38.1 64.6 35.7 39.1 44.3 344.9 44.8 35.7 41.2 49.0 39.0 44.8 45.5 27.7 62.7 89.9 13.5 29.2 37.8 36.5 46.9 48.6 42.4 36.4 67.7 36.4 45.9 31.9 69.0 77.8 26.2 37.2 42.7 44.4 64.1 51.1 34.8 43.3 16.2 15.0 22.1 18.5 13.9 19.3 12.1 16.2 18.4 16.5 11.4 19.7 18.9 15.9 12.9 26.1 8.3 14.4 21.2 34.5 34.9 34.6 35.7 33.7 33.5 36.8 37.0 34.0 38.8 38.9 36.0 11.8 9.6 17.8 17.3 18.6 54.2 13.5 15.2 29.6 17.8 19.7 14.2 23.1 7.2 12.2 5.5 14.6 19.6 26.4 19.6 1.9 7.7 30.4 19.3 15.3 15.0 20.4 28.6 23.9 8.6 42.4 16.5 10.2 18.4 1.3 15.8 20.7 25.0 17.5 18.5 18.6 19.9 8.2 19.5 20.8 52.5 15.2 15.2 24.9 9.4 19.0 17.5 21.6 16.6 25.0 11.2 11.8 15.4 14.1 19.0 18.5 10.7 14.8 13.2 13.1 15.7 12.1 12.7 11.0 40.2 60.4 27.2 17.8 12.7 18.5 18.6 DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 467.3;Suprabasal keratinocytes: 332.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Approved "Plasma membrane,Cytosol" NA NA 9700 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA026605: AB_1847464, HPA064789: AB_2685352" "unprognostic (2.81e-1)" "unprognostic (9.70e-2)" "unprognostic (3.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.01e-2)" "unprognostic (3.29e-1)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" 14.5 6.2 13.0 6.8 13.6 5.4 10.4 12.6 12.8 13.6 22.8 13.5 4.8 13.5 5.6 19.0 7.7 5.9 19.3 11.8 14.8 6.9 12.6 10.5 11.1 7.9 8.1 8.0 9.3 20.6 5.3 9.1 8.3 11.9 8.5 24.9 9.4 11.0 5.6 30.9 7.2 10.9 7.8 13.1 7.0 6.9 11.2 4.8 7.4 4.7 15.6 9.5 15.1 10.7 18.2 1.9 13.1 3.5 7.8 5.8 17.1 2.5 2.3 4.7 4.8 9.4 16.6 20.4 4.4 5.6 9.6 39.7 11.8 10.0 4.0 9.0 4.1 6.8 4.8 11.8 4.8 7.9 3.8 3.9 10.6 3.9 4.7 10.8 11.3 10.2 11.9 9.9 2.8 17.0 6.9 4.9 7.5 12.9 5.6 6.3 11.1 2.0 6.8 13.5 20.3 4.8 15.8 23.1 16.1 8.7 30.5 2.1 10.8 3.9 7.4 8.4 2.2 2.2 2.7 22.1 5.0 1.5 8.7 7.7 2.0 2.6 2.3 2.4 3.0 10.8 3.0 2.3 2.2 4.6 2.4 2.6 2.8 6.7 3.5 18.3 4.0 1.9 13.0 13.6 12.6 12.8 11.8 14.8 7.9 8.1 8.3 7.8 11.2 10.7 62.2 35.3 27.0 160.6 37.8 467.3 172.4 128.6 30.7 110.7 56.8 40.6 149.3 38.6 82.3 29.5 308.6 33.0 66.9 47.0 23.5 63.8 40.0 68.4 142.9 71.9 87.7 140.0 143.7 93.1 27.6 67.3 21.9 54.6 26.0 155.2 102.4 47.2 32.8 195.2 202.0 56.7 73.2 16.3 55.8 16.6 60.3 36.1 90.7 66.5 25.2 96.5 16.5 74.9 24.3 191.4 45.1 74.1 30.8 104.2 24.7 12.8 102.4 168.7 32.9 84.6 66.3 51.3 46.3 52.8 332.0 34.2 25.1 25.1 38.1 84.2 DMKN ZD52F10 ENSG00000161249 Dermokine Q6E0U4 19 35497220-35513658 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "skin 1: 4799.0" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 8514.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.7" "Group enriched" "Detected in many" 5 "NK-cells: 11.7;T-cells: 6.4" "Cell line enhanced" "Detected in many" "A-431: 150.1;CACO-2: 182.0;CAPAN-2: 153.9;HBEC3-KT: 236.4;RPTEC TERT1: 232.2" "Region enhanced" "Detected in all" "basal ganglia: 51.9" "Low region specificity" "Detected in all" HPA029406 Enhanced Approved Nucleoplasm,Cytosol "Secreted in other tissues" NA NA 47000000 "Cluster 22: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" "HPA029406: AB_10603661" "unprognostic (5.70e-2)" "unprognostic (2.36e-2)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-2)" "unprognostic (3.82e-2)" "unprognostic (3.23e-1)" "unprognostic (1.03e-1)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.37e-6)" "unprognostic (3.50e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" 13.8 9.3 6.5 1.1 11.7 1.7 195.4 7.3 7.0 262.7 16.1 11.0 5.6 16.1 14.4 221.3 73.9 1.8 11.9 5.9 7.0 50.3 4.7 22.3 1.2 18.4 7.2 35.0 59.7 87.1 58.1 2.2 17.8 19.3 4.9 1.9 69.5 14.6 20.1 4799.0 8.4 4.2 6.6 2.9 19.9 4.1 6.6 12.2 60.0 0.2 50.6 14.1 378.5 6.2 150.1 24.0 0.0 0.1 5.7 8.7 40.5 0.5 19.6 1.0 1.4 182.0 153.9 0.0 57.5 1.4 7.3 81.8 44.5 236.4 1.9 0.7 43.0 0.0 0.0 41.3 6.8 0.0 0.5 77.6 62.3 4.2 133.2 13.4 0.0 0.0 0.8 0.2 0.5 130.2 0.1 0.0 129.2 107.9 9.7 0.2 0.0 6.2 232.2 97.4 0.4 0.0 35.6 0.1 14.9 36.7 58.5 0.0 0.3 22.3 67.1 0.8 0.6 0.9 0.3 1.1 18.8 0.3 1.4 0.0 0.0 0.0 6.4 0.0 5.5 1.7 0.5 3.1 0.0 0.1 0.1 2.0 0.0 11.7 0.0 0.2 0.0 1.3 6.5 11.7 7.3 7.0 5.9 7.0 18.4 7.2 17.8 6.6 6.6 6.2 13.9 105.8 115.3 1.0 5.9 1623.7 143.2 169.9 39.3 1.7 71.8 164.3 20.4 100.1 107.6 204.1 0.0 1.0 6.7 6.0 230.9 138.0 15.9 181.5 9.0 27.7 49.3 2.7 6.9 140.2 1.5 47.1 27.0 107.8 7.6 2.4 12.1 4.0 1.0 0.0 5.3 8.0 46.8 0.3 287.0 98.0 13.1 2.8 305.9 0.0 2.6 15.1 28.8 0.0 0.4 146.1 9.3 15.8 3.4 94.0 0.2 7.6 270.2 0.8 0.0 0.9 22.9 7.6 31.4 34.0 8514.1 2.3 15.0 0.2 14.2 77.4 DRAP1 NC2-alpha ENSG00000175550 "DR1 associated protein 1" Q14919 11 65919274-65921563 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 813.2;Suprabasal keratinocytes: 1015.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 1032.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006790 Uncertain Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Cytosol "HPA006790: AB_1078702" "unprognostic (1.69e-2)" "unprognostic (1.02e-2)" "unprognostic (1.01e-1)" "unprognostic (3.01e-2)" "unprognostic (1.84e-2)" "unprognostic (4.06e-2)" "unprognostic (4.89e-3)" "unprognostic (5.58e-2)" "unprognostic (8.47e-2)" "unprognostic (4.23e-2)" "unprognostic (1.98e-1)" "unprognostic (3.82e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.96e-5)" "unprognostic (1.62e-1)" 87.4 86.4 119.0 71.0 120.8 96.8 80.3 121.2 162.8 91.0 103.7 104.4 56.1 89.3 27.9 107.5 74.0 34.9 129.2 120.3 132.4 75.0 76.2 75.1 71.0 119.9 119.6 67.4 73.3 62.6 81.2 43.1 121.5 73.1 21.1 25.1 58.3 48.0 197.1 112.5 62.9 40.2 118.1 85.6 69.9 173.1 120.7 96.6 118.9 78.5 39.2 84.2 83.4 131.6 578.7 226.8 108.3 200.0 99.9 195.3 75.9 634.9 273.2 344.1 223.6 85.6 302.7 142.2 277.3 420.3 395.5 222.7 42.7 292.0 138.2 187.7 70.1 173.4 103.8 85.4 186.0 145.8 228.2 123.7 126.6 365.8 246.7 191.4 142.2 138.9 78.5 223.6 377.4 301.9 255.0 263.6 167.5 73.1 575.9 216.3 107.1 305.4 113.6 82.3 122.2 137.7 149.6 137.8 348.9 46.1 188.2 104.8 413.0 470.1 461.4 1032.4 556.2 201.8 186.6 149.9 490.1 91.4 650.8 146.5 118.9 290.5 131.0 311.9 117.5 139.5 116.3 136.6 183.2 124.2 114.6 123.3 164.6 194.6 538.9 136.8 148.5 112.7 119.0 120.8 121.2 162.8 120.3 132.4 119.9 119.6 121.5 118.1 120.7 131.6 116.7 6.4 30.5 9.1 131.8 813.2 199.3 238.8 139.5 56.9 122.9 189.0 32.9 64.3 89.8 130.6 35.5 136.6 166.9 111.7 283.7 202.8 128.9 78.6 142.8 110.6 151.9 195.7 11.5 170.7 161.9 130.2 58.1 98.9 238.0 78.9 92.1 96.4 298.5 63.9 10.8 120.4 142.4 152.4 462.0 85.7 179.3 208.1 247.3 14.0 241.9 79.9 286.3 11.6 22.9 289.9 126.2 173.0 131.7 423.3 144.8 257.8 54.4 47.9 92.1 90.1 194.1 131.0 171.1 163.8 1015.8 174.4 197.2 107.1 125.0 425.3 DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 228.8" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 166.5" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075379 Enhanced NA NA 27000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" 0.2 0.0 0.0 0.1 0.0 0.2 9.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 228.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 2.6 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 14.1 0.3 0.0 2.2 0.9 0.1 0.4 29.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.4 0.0 0.0 3.6 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.5 166.5 0.4 0.6 0.0 0.0 0.3 DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 564.4" "Group enriched" "Detected in some" 25 "Basal keratinocytes: 117.4;Suprabasal keratinocytes: 315.7" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "hTCEpi: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" 0.4 0.0 0.0 0.0 0.0 0.2 24.7 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 1.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.6 0.0 2.0 564.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 2.1 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.6 0.0 3.3 0.9 1.7 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.1 0.1 0.0 0.0 8.6 3.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.2 6.5 315.7 0.0 0.2 0.0 0.1 0.0 DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056571 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Squamous epithelial cells: 51.6;Suprabasal keratinocytes: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "hTCEpi: 109.8;hTERT-HME1: 92.6" "Low region specificity" "Detected in all" HPA073007 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA073007: " "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (6.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (8.67e-3)" "unprognostic (7.38e-3)" "unprognostic (7.74e-3)" "prognostic unfavorable (8.84e-6)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "unprognostic (9.46e-2)" 13.1 10.0 23.3 7.6 28.4 3.6 11.5 19.5 27.5 27.0 7.5 8.4 4.1 14.6 3.9 64.1 10.1 8.7 22.2 24.2 21.2 10.6 5.2 24.9 10.2 25.8 27.2 8.7 7.0 6.2 7.2 14.1 22.3 11.5 3.8 2.6 13.2 7.9 23.1 65.6 7.9 6.7 19.5 26.2 9.1 12.0 27.2 8.1 9.1 20.5 10.8 13.5 45.5 38.4 21.3 4.4 5.2 11.9 16.4 14.1 6.2 21.0 39.8 20.4 14.7 5.8 10.6 5.8 5.7 31.3 10.3 24.6 19.8 76.0 13.8 5.0 8.1 27.8 10.9 10.3 13.3 25.1 16.2 14.8 109.8 26.5 92.6 14.1 19.8 16.8 16.2 16.4 16.5 5.9 18.7 35.2 12.9 5.9 37.6 15.5 4.5 15.6 8.5 9.1 6.5 19.0 9.4 8.5 14.9 4.2 3.0 59.4 26.0 39.1 25.3 41.7 65.4 7.9 7.9 9.3 21.7 41.5 12.7 0.9 3.4 1.7 5.3 10.3 7.2 0.9 6.3 3.8 4.7 0.5 4.5 4.1 1.3 2.5 10.3 7.1 4.5 1.7 23.3 28.4 19.5 27.5 24.2 21.2 25.8 27.2 22.3 19.5 27.2 38.4 17.0 9.6 1.1 0.0 2.9 117.3 31.5 13.5 21.1 4.9 6.6 7.2 18.9 0.0 5.2 0.0 0.0 0.6 13.4 1.6 1.9 3.1 1.7 2.9 8.1 18.7 2.4 1.7 5.5 2.6 4.3 7.8 0.5 2.8 0.0 1.3 23.6 0.9 8.1 0.0 4.4 2.5 0.0 16.7 12.0 0.5 8.7 9.0 21.4 5.6 10.3 0.9 9.2 5.5 20.2 12.1 1.3 4.9 1.6 17.5 0.6 1.3 1.5 1.0 26.3 3.3 8.6 3.5 5.5 51.6 135.2 1.2 7.3 4.1 3.4 29.3 EFNA3 "Ehk1-L, EPLG3, LERK3" ENSG00000143590 "Ephrin A3" P52797 1 155078837-155087538 "Predicted membrane proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 30.9;skin 1: 102.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.2;Basal squamous epithelial cells: 44.3;Extravillous trophoblasts: 30.0;Squamous epithelial cells: 32.6;Suprabasal keratinocytes: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 46.3;SCLC-21H: 26.8;T-47d: 25.3" "Low region specificity" "Detected in all" CAB010494 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "CAB010494: AB_2097783" "unprognostic (3.75e-2)" "unprognostic (1.53e-2)" "unprognostic (1.56e-2)" "unprognostic (1.51e-2)" "unprognostic (3.88e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.86e-2)" "unprognostic (3.56e-1)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.66e-10)" "unprognostic (2.83e-3)" "unprognostic (6.38e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-3)" 1.3 2.1 14.0 0.7 15.1 0.2 5.2 7.4 23.3 13.1 5.0 3.5 1.0 1.3 3.8 30.9 0.8 0.6 1.0 17.9 12.3 1.6 3.4 0.7 0.6 13.9 10.6 1.6 1.1 5.6 14.5 0.8 13.3 2.3 3.6 3.2 5.5 0.5 0.8 102.4 1.5 0.7 8.7 1.2 1.1 3.6 12.5 1.1 1.0 0.6 2.4 0.9 28.0 15.4 6.1 1.5 2.6 16.6 2.9 1.5 1.9 0.3 0.5 0.7 1.0 1.0 2.6 4.7 2.7 0.6 1.5 10.0 18.4 3.7 0.6 2.8 4.0 0.6 0.6 1.3 0.3 0.7 3.3 0.8 4.5 0.3 1.1 7.7 1.4 3.0 3.0 2.9 0.6 8.3 0.9 2.5 1.8 46.3 4.8 6.0 1.5 15.6 2.0 0.2 26.8 8.2 1.0 17.7 0.5 2.3 25.3 0.9 0.5 1.8 5.1 0.8 0.5 5.6 2.6 1.1 3.1 2.4 0.2 0.0 0.6 0.8 0.8 0.8 0.8 1.0 0.6 0.4 1.4 1.2 0.9 0.5 0.0 2.7 0.3 1.1 1.6 0.4 14.0 15.1 7.4 23.3 17.9 12.3 13.9 10.6 13.3 8.7 12.5 15.4 3.8 0.0 0.6 2.0 2.1 63.2 3.8 13.6 44.3 1.5 16.9 12.2 0.2 0.0 4.4 0.0 0.0 1.1 3.5 8.6 1.9 3.9 0.6 1.6 0.7 4.2 1.2 0.0 6.5 2.9 30.0 1.5 0.0 1.6 0.0 1.6 1.1 1.1 2.1 3.3 7.9 9.1 2.0 1.2 6.8 1.1 1.2 1.3 8.8 1.0 0.8 9.6 3.1 0.0 1.3 3.2 7.4 0.4 0.4 9.9 6.1 1.3 1.1 1.3 0.0 1.1 8.8 6.5 9.3 32.6 108.8 2.9 2.2 10.1 7.4 3.8 EPPK1 EPIPL1 ENSG00000261150 "Epiplakin 1" P58107 8 143857324-143878467 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 16.1" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 137.1;Suprabasal keratinocytes: 274.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.3;EFO-21: 13.3;HaCaT: 13.8;HeLa: 26.8;MCF7: 20.2;SK-BR-3: 9.3" "Not detected" "Not detected" "HPA066808, HPA067357, HPA069333" Approved Enhanced "Intermediate filaments" NA NA 1200000 "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "HPA066808: AB_2685726, HPA067357: AB_2685826, HPA069333: AB_2686123" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (5.52e-5)" "unprognostic (2.85e-2)" "unprognostic (5.86e-3)" "unprognostic (4.90e-2)" "unprognostic (8.73e-2)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.35e-1)" "unprognostic (1.97e-3)" "unprognostic (5.94e-3)" "unprognostic (4.35e-1)" "unprognostic (3.68e-3)" "unprognostic (5.08e-3)" 0.2 0.0 0.4 0.3 0.4 0.1 0.9 3.9 0.5 0.5 1.3 3.3 2.1 2.4 0.3 1.7 2.0 0.2 0.1 0.8 0.6 1.2 0.3 0.9 0.1 2.5 2.7 0.0 0.7 0.2 0.2 0.2 1.7 1.4 0.6 0.0 2.2 1.4 0.2 16.1 2.7 0.9 1.6 1.2 2.1 1.8 0.7 0.1 0.2 0.0 0.2 1.8 0.9 0.4 7.9 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 7.4 0.5 0.0 13.3 0.0 0.0 13.8 1.4 0.1 0.0 0.0 3.4 0.0 26.8 4.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 20.2 0.0 0.0 1.4 1.8 0.0 0.0 0.1 0.0 0.0 4.9 2.3 0.0 2.2 9.3 0.0 1.2 7.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 3.9 0.5 0.8 0.6 2.5 2.7 1.7 1.6 0.7 0.4 0.7 19.2 9.2 1.0 1.1 137.1 20.3 8.2 8.0 0.6 32.7 25.0 27.9 11.5 4.4 14.7 0.0 2.5 0.0 48.1 0.0 11.3 0.5 12.6 0.5 3.2 6.0 0.0 0.3 14.7 0.3 2.4 12.2 10.1 0.0 0.6 0.7 4.4 0.3 0.0 0.0 14.5 12.2 0.0 8.2 0.3 0.0 0.4 16.0 0.0 0.0 0.6 0.0 0.0 0.1 31.9 21.7 0.0 0.2 8.6 28.2 7.0 24.2 0.2 0.0 0.0 5.2 1.5 1.0 10.6 274.3 6.2 1.2 0.1 28.4 31.5 FAM83C "C20orf128, dJ614O4.7" ENSG00000125998 "Family with sequence similarity 83 member C" Q9BQN1 20 35285731-35292425 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 33.3;skin 1: 42.3;vagina: 15.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.9;Basal squamous epithelial cells: 17.6;Early spermatids: 11.8;Squamous epithelial cells: 26.1;Suprabasal keratinocytes: 64.2" "Cancer enhanced" "Detected in some" "cervical cancer: 9.9;head and neck cancer: 18.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034227, HPA049978" Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB034227: AB_1562876, HPA049978: AB_2680979" "unprognostic (3.76e-2)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (3.61e-1)" "unprognostic (1.57e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (9.17e-5)" "unprognostic (9.89e-3)" "unprognostic (1.71e-1)" "unprognostic (5.01e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.2 5.3 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 4.2 0.0 0.1 42.3 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 2.1 0.6 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 27.9 1.1 0.0 17.6 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.8 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.2 6.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.3 1.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 26.1 64.2 0.0 0.0 0.0 0.1 1.9 FBXO46 "20D7-FC4, Fbx46, FBXO34L" ENSG00000177051 "F-box protein 46" Q6PJ61 19 45710629-45730896 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HeLa: 84.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049390 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Vesicles" Cytosol "HPA049390: AB_2680742" "unprognostic (9.02e-3)" "unprognostic (1.01e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (9.33e-2)" "prognostic favorable (5.44e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.08e-1)" "unprognostic (2.06e-1)" "unprognostic (6.13e-2)" "prognostic favorable (8.11e-4)" "unprognostic (9.77e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (5.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (5.09e-6)" 7.5 7.2 10.6 11.1 11.0 9.2 8.9 9.5 12.6 13.5 18.4 11.7 7.6 13.6 7.5 21.4 10.3 5.1 8.5 8.8 12.2 7.9 10.5 7.4 14.7 8.7 9.6 14.1 9.6 5.8 9.4 6.6 11.5 9.8 7.5 9.9 10.1 5.3 11.4 13.4 11.1 6.3 6.0 14.4 10.8 12.3 9.9 11.1 10.4 5.4 13.9 9.3 13.0 20.9 14.0 21.5 16.2 18.9 4.1 7.3 18.3 7.1 4.0 5.6 6.5 17.8 17.9 24.1 9.5 4.0 7.9 19.9 12.1 9.1 4.2 30.0 25.5 19.6 84.1 9.8 6.2 8.7 24.2 6.1 8.1 9.5 5.9 14.0 8.4 29.4 15.6 28.4 4.6 13.2 20.3 10.2 10.2 13.0 7.3 27.3 9.0 22.6 6.7 16.3 16.1 14.1 11.4 23.7 9.4 15.3 20.1 10.7 9.6 11.8 10.6 6.5 12.0 27.2 41.0 16.1 13.1 12.3 9.8 4.6 1.1 1.2 1.8 0.9 1.2 2.1 1.3 1.3 0.8 3.8 1.2 1.4 3.3 0.6 1.2 1.3 1.4 0.7 10.6 11.0 9.5 12.6 8.8 12.2 8.7 9.6 11.5 6.0 9.9 20.9 4.8 9.6 4.8 6.2 6.5 26.0 10.0 5.7 9.1 3.3 12.7 8.5 5.4 10.0 6.1 7.3 2.1 7.9 3.4 16.3 1.9 6.5 2.9 8.0 5.1 5.2 7.3 5.9 6.5 4.9 19.0 3.6 6.1 9.2 3.8 11.4 4.2 21.1 3.7 11.8 5.5 12.7 0.0 5.7 8.8 3.1 5.6 3.3 5.4 5.6 5.6 4.0 7.2 4.0 6.1 6.9 12.2 1.9 5.5 8.0 6.3 2.2 7.2 3.4 0.0 3.6 4.7 6.5 4.6 13.3 35.8 12.4 5.1 4.9 9.3 11.1 FLG ENSG00000143631 Filaggrin P20930 1 152302165-152325239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 458.2" "Cell type enriched" "Detected in some" 13 "Suprabasal keratinocytes: 44.0" "Cancer enriched" "Detected in some" 7 "melanoma: 11.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.1;NTERA-2: 3.1;TIME: 2.1;U-2 OS: 2.4;U-2197: 2.6;WM-115: 2.0" "Not detected" "Not detected" "CAB002210, HPA027505, HPA030188, HPA030189" Enhanced Enhanced "Cytoplasmic bodies" NA NA 3800000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Cytoplasmic bodies" "CAB002210: AB_563731, HPA027505: AB_10600107, HPA030188: AB_10601749, HPA030189: AB_10601999" "unprognostic (3.37e-2)" "unprognostic (3.76e-1)" "unprognostic (8.83e-2)" "unprognostic (2.96e-3)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (9.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" "unprognostic (1.45e-1)" "unprognostic (4.28e-2)" "unprognostic (4.15e-2)" "unprognostic (7.41e-3)" 0.3 0.4 0.7 0.1 0.3 0.1 15.7 0.3 0.4 6.5 0.0 0.2 0.0 0.5 0.0 12.0 0.4 0.1 0.4 0.3 1.4 0.4 0.2 0.2 0.0 1.6 0.9 0.9 0.4 0.0 0.2 0.0 1.2 0.2 0.0 0.2 2.7 0.0 1.8 458.2 0.1 0.0 0.8 0.1 0.2 0.3 0.8 0.5 0.3 0.0 0.5 0.1 4.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.0 10.1 0.0 0.0 0.0 1.1 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 2.1 0.8 2.4 2.6 1.9 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.3 0.4 0.3 1.4 1.6 0.9 1.2 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.0 0.0 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.0 44.0 0.0 0.1 0.1 0.0 0.0 FLG2 IFPS ENSG00000143520 "Filaggrin family member 2" Q5D862 1 152348735-152360006 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 483.9" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 24.2" "Cancer enriched" "Detected in some" 8 "melanoma: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028699 Approved NA NA 21000000 "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA028699: AB_10601905" "unprognostic (2.58e-1)" "unprognostic (2.33e-1)" "unprognostic (3.08e-1)" "unprognostic (6.85e-2)" "unprognostic (6.59e-3)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" "unprognostic (2.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" 0.3 0.0 0.1 0.0 0.0 0.1 32.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 483.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 1.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 1.1 0.0 1.0 0.2 0.1 0.2 0.0 24.2 0.0 0.0 0.1 0.0 0.3 FRMD8 "FKSG44, FLJ90369, iTAP" ENSG00000126391 "FERM domain containing 8" Q9BZ67 11 65386621-65413525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002861 Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Centriolar satellite" "Nucleoplasm, Cytosol" "HPA002861: AB_1078878" "unprognostic (1.54e-1)" "unprognostic (4.07e-1)" "unprognostic (6.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (9.94e-5)" "unprognostic (9.12e-3)" "unprognostic (1.51e-2)" "unprognostic (6.36e-3)" "unprognostic (1.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.19e-3)" "unprognostic (1.47e-2)" "unprognostic (7.36e-3)" "unprognostic (3.34e-1)" "unprognostic (2.91e-2)" 19.8 17.5 9.6 11.8 11.0 13.0 19.7 12.2 14.5 20.8 9.1 15.0 11.7 14.6 5.3 37.3 15.8 11.6 17.1 13.1 7.9 19.7 13.4 23.5 15.6 12.9 11.3 12.2 23.0 4.0 11.6 10.4 11.4 15.8 6.7 1.7 18.0 6.5 14.8 34.0 23.8 6.6 9.5 40.8 13.4 18.0 11.5 11.1 17.8 5.1 13.6 14.6 26.4 16.2 17.8 22.1 8.7 20.4 23.0 12.0 15.6 20.1 18.1 16.7 12.7 21.2 28.5 21.9 41.9 27.6 11.6 30.3 11.3 16.9 7.0 38.8 10.6 29.9 21.5 11.7 12.4 16.9 44.8 14.9 13.2 15.7 8.2 8.9 26.6 23.2 25.5 23.5 18.3 23.9 26.6 24.6 10.2 13.0 28.7 33.7 16.6 25.2 13.5 21.8 18.9 14.0 15.0 60.1 47.7 7.7 22.0 13.7 23.6 18.4 19.7 26.1 12.3 41.0 22.5 20.4 16.0 10.7 129.8 1.1 12.4 17.7 13.1 13.2 14.1 12.5 9.6 16.7 11.3 9.6 8.8 9.8 23.0 8.2 19.6 13.4 10.8 12.3 9.6 11.0 12.2 14.5 13.1 7.9 12.9 11.3 11.4 9.5 11.5 16.2 30.3 3.2 5.8 2.0 20.5 54.3 22.5 17.7 6.2 5.4 15.4 12.6 7.4 12.8 13.8 12.9 0.0 6.4 25.8 29.3 7.9 21.0 22.3 20.1 12.1 24.8 13.1 24.0 13.4 29.1 15.5 13.0 10.7 23.1 14.0 27.3 37.5 11.0 16.0 5.0 4.9 20.5 8.2 20.2 68.7 4.6 6.2 18.7 19.6 10.3 21.6 4.3 18.6 5.0 10.3 33.8 14.0 7.2 11.9 28.1 32.8 4.6 14.3 4.5 6.6 11.4 14.4 5.3 9.6 24.9 83.5 11.4 21.9 35.2 14.6 35.7 G3BP1 "G3BP, HDH-VIII" ENSG00000145907 "G3BP stress granule assembly factor 1" Q13283 5 151771045-151812911 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity, Transport" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004052, CAB037068" Supported Supported Cytosol NA NA 280000 "Cluster 13: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB037068: AB_1840864, HPA004052: AB_1849348" "unprognostic (1.31e-1)" "unprognostic (3.94e-2)" "unprognostic (1.19e-3)" "unprognostic (1.28e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "unprognostic (1.03e-3)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.33e-4)" "unprognostic (1.97e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (3.88e-2)" 52.3 46.8 32.9 60.2 36.1 27.5 54.1 42.8 44.6 42.0 41.0 47.8 34.8 42.5 33.1 54.8 51.0 38.8 51.0 30.7 36.1 57.1 69.0 36.1 78.3 34.5 35.7 62.5 30.4 41.5 16.5 58.2 35.8 41.3 50.6 18.3 31.8 37.3 112.2 43.4 33.9 47.8 35.0 46.7 40.3 65.5 38.6 66.0 42.6 92.1 85.7 66.3 31.9 43.3 204.9 267.0 177.0 96.3 253.2 119.2 232.4 204.1 190.6 290.6 348.6 413.7 310.3 384.7 307.0 188.0 231.6 210.9 319.7 395.6 333.7 122.5 173.8 232.9 201.1 334.8 128.8 281.6 163.9 123.4 186.7 243.7 232.2 98.7 209.7 140.9 191.3 173.3 254.5 179.7 273.9 142.4 231.4 146.0 209.6 254.3 235.1 187.2 163.1 290.5 195.2 132.0 200.8 307.0 319.3 169.2 246.3 174.7 238.2 202.0 239.7 187.3 364.0 104.9 171.3 305.0 132.2 229.6 337.8 132.2 102.3 84.7 189.2 135.4 255.3 168.8 215.6 186.7 141.0 160.0 201.8 193.2 37.8 203.7 134.1 134.7 249.2 287.2 32.9 36.1 42.8 44.6 30.7 36.1 34.5 35.7 35.8 35.0 38.6 43.3 88.9 19.2 41.4 32.7 112.0 239.5 101.3 82.4 148.0 37.1 74.8 60.7 62.3 44.3 66.2 64.4 16.7 94.0 91.7 47.3 78.2 69.6 49.6 80.6 104.4 112.1 50.2 96.1 25.7 53.0 94.6 98.0 70.3 87.2 73.6 73.8 76.8 169.4 78.2 57.2 30.6 59.4 50.8 81.2 195.0 30.1 65.0 73.3 87.2 37.5 83.7 54.3 45.3 29.7 45.3 59.2 42.9 57.2 89.3 160.0 33.5 80.0 74.2 36.6 39.5 111.6 90.7 58.0 89.3 155.6 256.4 67.3 99.6 72.2 78.5 98.0 HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105653-69118719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.5;urinary bladder: 92.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 162.3;Basal prostatic cells: 51.6;Basal respiratory cells: 107.1;Suprabasal keratinocytes: 158.6;Urothelial cells: 115.5" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 52.5;PC-3: 270.5;RT4: 111.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA031554, CAB033850" Supported Approved Microtubules NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" 0.8 0.5 0.9 0.7 1.2 0.9 7.5 1.3 1.3 4.6 0.9 5.3 2.9 0.9 1.1 33.5 1.2 4.8 0.7 0.6 1.1 1.1 1.3 20.1 0.4 1.0 1.3 1.4 1.3 0.4 1.7 3.4 1.1 3.7 3.1 0.8 5.4 1.5 1.2 9.7 2.2 0.6 0.4 0.8 12.8 3.5 1.0 0.5 5.9 0.9 2.8 92.8 10.3 1.0 3.5 17.1 1.0 0.9 0.3 0.4 6.6 1.1 0.4 1.0 0.4 3.4 9.0 0.7 2.0 0.4 4.0 52.5 2.9 31.5 1.0 0.2 1.3 0.0 0.2 0.6 0.1 0.3 0.9 0.5 8.6 1.0 3.0 4.0 0.7 0.6 0.1 0.4 0.3 1.8 1.2 0.7 15.5 18.7 270.5 2.0 0.1 0.2 28.3 111.6 19.2 0.8 1.8 0.1 0.3 3.1 0.6 0.8 0.3 0.9 0.9 29.9 1.8 1.0 0.9 0.2 1.0 0.0 0.6 0.1 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.9 1.2 1.3 1.3 0.6 1.1 1.0 1.3 1.1 0.4 1.0 1.0 4.2 0.0 30.8 0.7 0.2 162.3 51.6 107.1 8.6 1.1 1.6 6.1 1.4 0.0 12.2 0.0 2.1 1.0 0.1 16.4 0.0 4.5 10.2 0.7 0.3 2.4 0.0 0.4 1.0 3.6 0.9 1.1 5.1 2.7 0.0 0.4 1.1 0.2 0.3 0.0 2.1 0.7 2.0 0.0 6.5 22.7 1.2 0.5 3.6 0.0 0.0 0.1 0.0 0.5 0.8 2.4 0.2 0.4 0.6 18.4 0.1 0.7 3.0 1.0 0.0 0.9 1.9 0.5 0.7 25.6 158.6 0.3 1.1 0.1 2.2 115.5 HEPHL1 DKFZp686F22190 ENSG00000181333 "Hephaestin like 1" Q6MZM0 11 94021354-94114208 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 4.5;lymphoid tissue: 9.5;skin 1: 3.8;vagina: 4.5" "Cell type enriched" "Detected in some" 5 "Basal keratinocytes: 10.5" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 1.4;HBEC3-KT: 2.6" "Region enriched" "Detected in single" 12 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA031517 Uncertain NA NA 260000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "HPA031517: AB_10603769" "unprognostic (9.16e-2)" "prognostic unfavorable (4.94e-4)" "unprognostic (2.40e-1)" "unprognostic (3.26e-6)" "unprognostic (3.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-2)" "unprognostic (6.71e-2)" "unprognostic (5.34e-1)" "unprognostic (1.09e-1)" "unprognostic (7.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (1.25e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 9.5 0.0 4.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 10.5 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.0 0.1 0.1 0.0 0.4 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Breast myoepithelial cells: 3.0;Spermatogonia: 1.2;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 31.2;HaCaT: 66.1;SK-BR-3: 36.0;T-47d: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA051634 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.7 10.5 0.0 31.2 0.5 0.0 18.4 1.9 4.4 2.8 1.5 2.7 0.5 0.0 0.4 0.0 2.0 66.1 8.0 2.1 1.6 0.0 6.4 0.0 8.4 0.0 0.0 0.0 6.6 0.0 15.4 0.0 6.0 0.0 0.0 0.1 11.8 0.0 11.5 20.1 0.0 0.0 0.3 6.6 2.7 0.0 0.4 0.0 0.0 6.0 0.0 0.0 10.4 36.0 4.9 7.4 28.1 0.1 0.0 0.1 13.1 0.2 4.2 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.7 3.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 2.4 0.1 0.0 0.0 0.0 0.0 IGFL3 UNQ483 ENSG00000188624 "IGF like family member 3" Q6UXB1 19 46120067-46124688 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 27.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.1;Basal respiratory cells: 1.7;Exocrine glandular cells: 6.5;Melanocytes: 1.8;Suprabasal keratinocytes: 8.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.7;CACO-2: 1.0;hTEC/SVTERT24-B: 1.2;U-2 OS: 1.3;U-87 MG: 2.4" HPA062776 Uncertain "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 28: Keratinocytes - Keratinization" "HPA062776: AB_2684866" "unprognostic (8.61e-2)" "unprognostic (6.26e-2)" "unprognostic (2.69e-1)" "unprognostic (4.78e-2)" "unprognostic (7.45e-3)" "unprognostic (2.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.90e-1)" "unprognostic (1.86e-4)" "unprognostic (2.86e-2)" "unprognostic (1.90e-1)" "unprognostic (3.69e-2)" 0.0 0.0 0.6 0.0 1.2 0.1 1.5 0.0 1.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.1 0.0 1.1 0.2 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.1 0.5 0.1 0.0 0.3 27.7 0.0 0.1 0.2 0.0 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.2 0.2 1.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.2 1.2 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 1.2 0.5 0.3 1.1 0.2 1.1 0.2 0.4 2.6 0.0 0.0 0.0 0.0 0.0 3.1 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 1.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 IMP3 "BRMS2, C15orf12, FLJ10968, MRPS4" ENSG00000177971 "IMP U3 small nucleolar ribonucleoprotein 3" Q9NV31 15 75639085-75648706 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060955, HPA061177" Enhanced Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Nucleoli" "HPA060955: AB_2684397, HPA061177: AB_2684445" "unprognostic (6.01e-2)" "unprognostic (5.40e-3)" "unprognostic (7.04e-2)" "unprognostic (7.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.22e-1)" "unprognostic (8.44e-2)" "unprognostic (4.51e-2)" "unprognostic (2.69e-3)" "unprognostic (1.18e-1)" "unprognostic (1.59e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-1)" "unprognostic (8.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.23e-1)" "unprognostic (3.22e-2)" 45.8 61.8 37.1 26.4 38.7 29.3 43.9 39.3 49.1 36.9 46.6 43.4 36.6 30.1 30.4 79.8 32.7 14.2 53.1 38.3 41.6 49.6 90.4 33.9 34.9 38.7 36.7 33.3 50.6 23.2 40.1 21.1 39.5 39.7 24.4 17.8 44.8 22.2 71.5 71.6 51.6 14.0 40.0 63.0 50.9 16.8 38.7 34.7 36.1 33.1 38.4 35.1 47.4 41.2 75.1 82.9 39.5 68.8 68.6 39.0 58.5 61.6 48.8 49.3 56.6 64.1 64.3 88.7 65.5 32.2 54.5 121.7 131.1 100.0 43.4 67.2 157.3 93.6 64.9 112.8 50.6 95.9 62.5 36.1 81.0 39.8 48.8 36.6 32.8 71.3 122.8 70.4 45.4 89.9 76.3 232.9 106.4 75.7 86.4 82.1 48.4 98.3 68.1 100.2 67.1 69.4 52.2 89.8 119.4 56.8 78.5 87.9 37.6 64.0 51.9 46.4 84.6 95.4 188.5 100.3 70.7 153.2 43.0 80.6 109.0 85.2 137.4 87.3 148.8 143.2 131.5 133.8 117.4 127.3 150.7 144.3 13.7 126.4 87.4 119.3 140.9 192.2 37.1 38.7 39.3 49.1 38.3 41.6 38.7 36.7 39.5 40.0 38.7 41.2 85.9 38.5 41.6 6.5 81.4 228.5 93.1 177.0 149.7 22.4 72.1 79.4 12.1 77.2 89.7 40.5 14.6 106.8 79.0 47.5 144.8 105.2 1.6 71.7 54.9 74.0 43.9 56.8 6.8 105.9 106.5 63.0 78.0 70.9 48.7 50.8 76.4 114.1 94.2 21.9 7.1 71.2 93.6 54.3 106.6 6.6 60.9 51.0 97.8 8.4 118.0 58.2 152.4 6.0 10.2 113.7 56.0 44.0 66.5 107.0 113.8 209.5 65.2 23.7 26.3 46.1 50.7 13.9 38.2 144.4 237.4 54.9 83.3 77.2 98.8 86.9 KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 90.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 103.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA077577 Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" 2.0 0.7 2.7 0.2 2.9 5.4 2.9 3.4 5.7 4.6 1.7 2.1 0.4 1.4 0.1 18.0 2.3 0.3 1.6 2.7 2.4 0.7 0.9 1.7 0.3 2.8 2.8 1.8 0.4 0.0 1.3 0.4 3.0 1.4 0.0 0.7 2.5 0.3 2.6 90.0 1.2 0.2 2.7 2.0 1.2 1.1 2.7 0.4 0.6 0.5 1.0 1.7 9.5 3.4 0.3 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 1.0 0.4 0.4 0.1 0.2 2.2 0.0 0.0 0.0 0.5 1.1 0.5 0.9 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.6 1.3 0.4 1.0 0.5 0.4 0.6 0.6 0.6 0.9 0.0 0.2 0.6 0.1 6.8 1.5 0.3 0.4 0.7 0.0 0.4 1.1 0.0 0.3 1.1 1.0 0.1 0.9 0.7 0.2 0.5 0.6 0.6 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 2.7 2.9 3.4 5.7 2.7 2.4 2.8 2.8 3.0 2.7 2.7 3.4 1.1 0.0 0.5 0.3 0.8 19.1 0.4 0.7 0.6 2.1 0.7 1.8 0.2 0.0 0.7 0.0 0.0 0.1 1.6 1.0 0.0 0.1 0.7 0.7 0.3 1.2 1.2 0.0 0.9 0.0 0.1 0.4 0.0 1.7 0.0 0.2 0.7 0.3 0.5 0.0 0.9 0.4 0.0 1.3 4.0 1.8 0.6 0.7 3.6 0.0 0.4 0.1 0.0 1.0 1.8 0.1 4.8 0.0 0.0 0.3 0.3 0.1 1.1 1.1 6.6 0.4 0.8 0.1 1.3 16.3 103.7 0.0 0.6 0.1 0.8 1.3 KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.0;Basal prostatic cells: 50.8;Ductal cells: 39.1;Prostatic glandular cells: 66.9;Suprabasal keratinocytes: 183.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 36.1;HaCaT: 16.2;HBEC3-KT: 10.5;hTCEpi: 12.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" 0.3 0.2 0.5 0.3 1.1 3.0 3.3 1.3 0.8 10.0 0.0 0.1 0.1 0.2 2.1 26.1 0.3 0.2 0.2 0.4 0.2 5.9 0.2 0.9 0.3 0.5 0.0 0.2 4.0 4.0 2.7 0.2 0.2 2.6 0.2 1.0 11.6 1.0 0.9 104.1 0.3 0.0 0.0 0.3 0.5 3.7 0.2 1.0 0.7 0.0 1.8 0.2 20.5 0.7 36.1 0.2 0.2 0.4 0.1 0.1 2.8 0.2 0.0 0.0 0.1 3.5 6.5 0.3 2.8 0.0 3.7 16.2 2.2 10.5 0.2 0.8 5.3 0.1 1.1 0.7 0.0 0.3 2.2 0.0 12.9 0.1 2.5 0.4 0.0 0.5 0.6 0.4 0.1 4.7 0.1 0.4 0.8 0.6 1.1 5.6 0.0 0.3 0.3 1.3 4.5 0.7 0.3 7.3 1.0 0.4 6.5 0.1 0.0 0.4 3.6 0.3 0.4 0.7 0.8 0.3 0.2 0.2 0.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.0 0.5 1.1 1.3 0.8 0.4 0.2 0.5 0.0 0.2 0.0 0.2 0.7 0.2 0.0 2.4 0.3 0.0 142.0 50.8 17.5 14.8 0.8 10.3 25.3 0.4 2.8 7.3 1.8 0.0 0.2 0.2 0.2 9.8 39.1 3.0 0.9 0.3 1.7 0.0 2.7 0.3 3.1 0.7 1.4 0.0 2.4 0.0 6.7 0.4 0.0 0.3 1.7 0.4 0.5 6.1 0.0 10.9 12.0 1.8 0.4 14.2 0.0 0.8 0.7 0.0 0.0 0.0 11.8 0.0 0.4 0.0 66.9 0.0 1.4 3.8 2.0 0.0 1.1 2.5 0.6 11.3 25.6 183.3 0.7 1.0 0.0 0.1 22.0 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 66.0;Suprabasal keratinocytes: 180.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 88.3;CAPAN-2: 112.2;HaCaT: 83.5" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 5.7 0.0 0.1 0.0 0.0 0.0 8.4 0.8 0.7 24.7 0.2 0.0 0.0 0.9 0.4 118.0 13.2 0.1 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.7 0.2 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 17.1 0.1 0.7 87.1 0.0 0.1 0.0 0.2 0.1 1.2 0.2 1.1 0.5 0.0 9.6 0.0 47.2 0.5 88.3 0.0 0.0 0.6 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.7 112.2 0.0 2.2 0.0 0.1 83.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 10.3 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.7 0.0 0.0 0.7 0.2 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.3 66.0 0.0 0.4 14.8 0.0 13.0 15.6 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.7 11.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 5.0 1.8 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 2.8 6.2 21.1 180.1 0.0 0.2 0.0 0.2 0.1 KPRP C1orf45 ENSG00000203786 "Keratinocyte proline rich protein" Q5T749 1 152759561-152762052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 329.1" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 20.0" "Group enriched" "Detected in some" 22 "head and neck cancer: 6.9;melanoma: 13.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 1.9;U-2197: 1.1" "Not detected" "Not detected" "HPA031988, HPA031990" Enhanced NA NA 27000000 "Cluster 61: Skin - Cornification" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA031988: AB_10671582, HPA031990: AB_2674102" "unprognostic (1.03e-1)" "unprognostic (2.67e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" 0.2 0.0 0.0 0.0 0.9 0.1 10.3 0.0 0.1 13.9 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 1.7 329.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 4.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 KRT1 "EHK1, KRT1A" ENSG00000167768 "Keratin 1" P04264 12 52674736-52680407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skin 1: 13006.6" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 10030.4" "Group enriched" "Detected in many" 5 "head and neck cancer: 313.8;melanoma: 478.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 2.3" "Lineage enriched" "Detected in single" 23 "T-cells: 2.3" "Group enriched" "Detected in some" 14 "HaCaT: 94.9;hTCEpi: 39.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002153, HPA017917, HPA062908" Enhanced NA NA 35000000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB002153: AB_563790, HPA017917: AB_1852192, HPA062908: AB_2684901" "unprognostic (8.05e-2)" "unprognostic (8.49e-3)" "unprognostic (5.06e-3)" "unprognostic (6.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (3.24e-1)" "unprognostic (1.30e-1)" "unprognostic (2.16e-1)" "unprognostic (9.24e-2)" "unprognostic (6.63e-2)" "unprognostic (3.23e-4)" "unprognostic (1.58e-1)" "unprognostic (3.40e-2)" "unprognostic (1.36e-1)" "unprognostic (1.09e-2)" 10.3 1.4 0.0 0.1 0.0 7.7 464.1 0.0 0.1 473.6 0.0 2.6 0.2 1.3 0.4 30.8 0.4 0.3 4.5 0.0 0.0 1.2 3.5 2.6 0.0 0.0 0.0 1.4 3.7 0.0 1.4 1.6 0.0 1.5 0.1 0.0 270.2 0.1 47.8 13006.6 2.0 0.2 0.0 1.6 2.1 1.9 0.0 76.8 2.0 0.8 0.5 0.9 1257.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.7 0.0 39.3 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1681.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 22.3 0.0 0.0 0.0 17.4 0.0 0.0 234.7 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 267.0 0.0 0.0 0.3 265.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 10.5 0.0 0.0 1.1 10030.4 0.0 7.8 0.0 0.3 0.4 KRT10 "CK10, K10, KPP" ENSG00000186395 "Keratin 10" P13645 17 40818117-40822614 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "skin 1: 15851.5" "Cell type enriched" "Detected in all" 5 "Suprabasal keratinocytes: 12515.3" "Group enriched" "Detected in all" 4 "head and neck cancer: 310.0;melanoma: 562.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "hTCEpi: 718.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000132, HPA012014" Enhanced "Secreted in other tissues" NA NA 18000000000 "Cluster 37: B-cells - Transcription" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB000132: , HPA012014: AB_1852195" "unprognostic (3.07e-1)" "unprognostic (5.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.60e-1)" "unprognostic (3.02e-2)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-2)" "unprognostic (8.10e-2)" 66.1 47.9 9.4 7.6 9.8 13.4 432.0 9.9 14.9 548.0 10.4 45.2 7.9 55.0 5.5 78.6 45.5 2.2 95.7 9.9 9.8 67.2 64.5 39.7 6.2 9.8 9.7 52.3 69.1 8.2 77.2 3.8 9.8 60.0 3.4 6.9 163.9 5.5 123.1 15851.5 48.2 4.0 9.8 56.8 58.0 64.9 9.8 44.0 53.5 5.8 13.7 48.5 1106.2 10.4 30.3 31.2 11.0 12.2 14.4 11.5 10.4 29.9 16.5 11.4 10.6 11.2 11.7 8.7 42.0 13.1 16.2 158.5 5.4 11.3 13.4 20.1 27.0 9.2 44.7 19.4 16.4 17.1 24.9 10.1 718.0 9.0 17.3 15.0 7.4 12.3 102.1 16.0 12.2 17.3 25.5 16.2 14.6 23.1 19.1 17.8 16.7 17.7 12.3 26.3 8.9 11.1 19.9 46.0 39.0 17.3 35.5 24.3 9.3 17.6 29.5 22.5 34.4 0.4 19.8 22.4 24.5 10.4 23.4 12.8 2.6 11.1 4.8 2.3 5.4 11.2 5.4 6.8 4.1 5.6 5.8 5.9 0.8 6.9 3.2 8.1 5.5 1.9 9.4 9.8 9.9 14.9 9.9 9.8 9.8 9.7 9.8 9.8 9.8 10.4 197.8 35.3 40.0 19.2 187.5 2239.7 320.6 370.2 255.6 47.0 304.4 328.2 194.2 174.5 197.2 112.2 20.9 117.4 163.2 138.9 305.2 232.5 150.4 174.3 172.2 170.0 181.1 87.7 19.1 376.9 295.7 204.5 126.9 164.5 74.3 87.0 159.5 237.6 105.0 21.9 16.3 237.6 195.3 90.3 350.7 65.6 216.6 116.8 393.1 20.6 100.1 221.4 162.7 17.6 35.0 236.0 149.8 174.9 311.6 342.0 155.3 233.2 116.8 68.6 105.2 141.0 167.7 345.1 121.2 295.0 12515.3 160.1 164.3 131.4 173.1 515.6 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT16 NEPPK ENSG00000186832 "Keratin 16" P08779 17 41609778-41615899 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 307.2;esophagus: 1025.8;skin 1: 360.7;vagina: 489.4" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 906.1;Basal prostatic cells: 596.6;Suprabasal keratinocytes: 1348.4;Urothelial cells: 506.9" "Group enriched" "Detected in many" 7 "cervical cancer: 713.1;head and neck cancer: 2720.5;melanoma: 712.9" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTCEpi: 816.8" "Not detected" "Not detected" "CAB000136, HPA000539" Approved Approved "Intermediate filaments" NA NA 1700000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000136: , HPA000539: " "unprognostic (3.95e-3)" "unprognostic (6.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-2)" "unprognostic (1.00e-2)" "unprognostic (7.14e-3)" "unprognostic (1.03e-3)" "unprognostic (2.05e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (8.23e-2)" "unprognostic (6.53e-8)" "unprognostic (3.81e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (3.61e-2)" 7.1 1.4 0.2 0.1 0.3 0.3 17.4 3.9 0.6 307.2 0.0 0.2 0.0 1.0 0.0 1025.8 0.7 2.4 0.5 1.0 0.0 0.8 0.4 0.2 0.1 0.0 0.0 0.3 0.7 0.0 1.4 0.1 0.1 6.3 0.0 0.0 180.6 37.7 0.5 360.7 0.2 0.1 0.0 0.2 0.6 2.6 0.0 16.9 0.3 0.0 112.1 5.5 489.4 0.4 20.0 1.7 0.0 0.0 0.2 0.0 0.2 1.5 0.4 0.5 0.2 0.3 4.9 0.1 2.9 0.1 0.2 24.8 0.0 5.6 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 816.8 0.3 17.6 0.0 0.0 0.0 0.3 0.0 0.2 0.5 0.0 0.3 0.0 127.1 0.7 0.0 0.2 98.1 0.8 6.2 0.0 0.0 57.1 1.5 0.0 0.9 0.0 0.0 0.2 0.0 1.6 4.5 0.4 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 3.9 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.3 906.1 596.6 70.1 16.5 0.0 37.8 27.1 0.1 0.0 94.6 1.8 0.0 0.1 0.6 0.0 0.0 1.0 0.0 2.6 0.6 9.2 0.0 0.0 0.0 5.8 3.2 11.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 94.1 0.0 0.3 1.1 64.0 0.0 0.0 0.0 0.0 0.0 0.0 82.7 0.0 0.0 0.0 127.3 0.0 0.0 17.1 0.0 0.0 0.0 9.3 0.0 0.3 88.1 1348.4 0.1 3.4 0.0 0.0 506.9 KRT2 "KRT2A, KRTE" ENSG00000172867 "Keratin 2" P35908 12 52644558-52652211 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "skin 1: 4660.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 265.4" "Cancer enriched" "Detected in some" 5 "melanoma: 23.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in single" "HEL: 2.0" "Group enriched" "Detected in some" 6 "amygdala: 1.7;hippocampal formation: 2.7" "Not detected" "Not detected" "HPA006299, CAB037321" Enhanced Approved "Golgi apparatus,Intermediate filaments,Cytosol" NA NA 9700000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments, Cytosol" "Golgi apparatus" "CAB037321: , HPA006299: AB_1079180" "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.56e-1)" "unprognostic (8.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.84e-1)" "unprognostic (3.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.76e-2)" "unprognostic (3.56e-7)" "unprognostic (6.43e-2)" "unprognostic (5.98e-3)" "unprognostic (6.69e-2)" "unprognostic (3.46e-1)" 3.0 0.5 0.0 0.1 0.0 1.0 81.9 0.0 0.0 0.8 0.0 0.9 1.6 0.4 0.3 1.1 0.1 0.0 1.7 0.0 0.0 0.5 1.2 1.0 0.5 0.0 0.0 0.5 1.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 1.6 0.0 47.8 4660.3 0.8 0.0 0.0 0.5 0.7 1.0 0.0 6.8 0.8 0.0 6.1 0.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.1 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.5 0.0 0.0 0.1 8.8 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 265.4 0.1 1.0 0.0 0.6 0.1 KRT77 KRT1B ENSG00000189182 "Keratin 77" Q7Z794 12 52689626-52703524 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 273.0" "Cell type enriched" "Detected in some" 8 "Suprabasal keratinocytes: 20.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 36 "HaCaT: 3.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045934 Enhanced Approved "Nuclear membrane,Plasma membrane" NA NA 1200000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Nuclear membrane, Plasma membrane" "HPA045934: AB_10960065" "unprognostic (3.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-1)" "unprognostic (2.61e-1)" "unprognostic (2.11e-1)" "unprognostic (2.06e-1)" 0.6 0.0 0.0 0.0 0.0 0.1 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 273.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.2 0.0 0.0 0.0 0.0 0.0 KRTDAP "KDAP, UNQ467" ENSG00000188508 "Keratinocyte differentiation associated protein" P60985 19 35487324-35495558 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skin 1: 6146.5;vagina: 1735.6" "Cell type enriched" "Detected in some" 15 "Suprabasal keratinocytes: 5277.0" "Group enriched" "Detected in many" 7 "head and neck cancer: 486.4;melanoma: 207.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "hTCEpi: 100.2" "Region enriched" "Detected in single" 6 "white matter: 1.6" "Not detected" "Not detected" HPA063474 Enhanced "Secreted in other tissues" NA NA 34000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA063474: AB_2685019" "unprognostic (4.55e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-1)" "unprognostic (6.11e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (3.80e-2)" "unprognostic (1.50e-1)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" 5.5 1.0 1.0 0.0 1.6 1.8 406.4 0.9 1.8 845.7 1.1 1.8 0.1 0.8 0.7 111.0 1.3 0.0 2.5 1.0 1.0 0.8 3.0 1.7 0.0 1.1 0.9 1.7 3.4 0.7 1.3 0.0 1.2 1.6 0.0 0.1 205.3 0.3 22.5 6146.5 1.3 0.1 1.0 0.8 1.5 3.3 0.9 20.0 2.5 0.3 90.1 0.7 1735.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.2 0.0 0.0 0.4 100.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.6 0.9 1.8 1.0 1.0 1.1 0.9 1.2 1.0 0.9 1.0 0.3 0.0 0.0 0.0 0.0 348.5 0.8 0.4 0.0 0.0 0.5 1.5 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 18.4 0.2 0.1 3.6 0.0 0.0 0.1 0.2 0.0 4.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.7 63.4 0.9 0.1 42.7 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 2.4 42.9 19.1 0.0 5277.0 0.0 1.5 0.0 0.0 0.5 LAMB4 ENSG00000091128 "Laminin subunit beta 4" A4D0S4 7 108023548-108130361 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 38.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 34.9;Basal squamous epithelial cells: 41.5;Early spermatids: 12.7;Late spermatids: 11.1;Suprabasal keratinocytes: 13.8" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.8;HMC-1: 1.1" "Low region specificity" "Detected in all" "HPA020242, HPA024247" Approved "Secreted to extracellular matrix" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "HPA020242: AB_2670388, HPA024247: AB_2671496" "unprognostic (7.41e-2)" "unprognostic (1.79e-1)" "unprognostic (4.85e-2)" "unprognostic (1.77e-1)" "unprognostic (3.79e-2)" "unprognostic (6.29e-4)" "unprognostic (8.90e-3)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.27e-2)" "unprognostic (1.23e-4)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" 0.1 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 1.9 0.0 0.1 0.1 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 38.9 0.2 0.0 0.0 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 2.0 0.0 34.9 0.0 0.0 41.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.7 0.0 0.0 5.9 0.0 12.7 3.8 0.1 0.8 0.0 0.0 2.1 0.2 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 1.9 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 5.1 0.5 4.2 13.8 1.4 0.0 0.1 0.0 0.1 LCE1A LEP1 ENSG00000186844 "Late cornified envelope 1A" Q5T7P2 1 152827473-152828097 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skin 1: 269.6" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 40.3" "Cancer enriched" "Detected in some" 6 "melanoma: 14.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 269.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 LCE1B "LEP2, SPRL2A" ENSG00000196734 "Late cornified envelope 1B" Q5T7P3 1 152811971-152813108 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 167.5" "Cell type enriched" "Detected in some" 18 "Suprabasal keratinocytes: 18.9" "Cancer enriched" "Detected in some" 10 "melanoma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 2.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.79e-1)" "unprognostic (1.24e-2)" "unprognostic (6.43e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 167.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 LCE1C LEP3 ENSG00000197084 "Late cornified envelope 1C" Q5T751 1 152804835-152806628 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 596.1" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 83.0" "Cancer enriched" "Detected in some" 6 "melanoma: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 1.0;HBEC3-KT: 2.2;hTEC/SVTERT24-B: 1.1;hTERT-HME1: 2.8" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.35e-2)" "unprognostic (5.95e-2)" "unprognostic (3.46e-2)" "unprognostic (3.35e-2)" 0.3 0.1 0.0 0.0 0.0 0.3 34.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 4.1 596.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 3.5 2.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 83.0 0.0 0.2 0.0 0.0 0.0 LCE1D LEP4 ENSG00000172155 "Late cornified envelope 1D" Q5T752 1 152796721-152798181 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 93 "skin 1: 80.8" "Cell type enriched" "Detected in single" 42 "Suprabasal keratinocytes: 12.6" "Cancer enriched" "Detected in single" 8 "melanoma: 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (7.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 80.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 LCE1E LEP5 ENSG00000186226 "Late cornified envelope 1E" Q5T753 1 152786214-152788426 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "skin 1: 61.4" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 18.3" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HaCaT: 10.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (9.92e-2)" "unprognostic (9.50e-2)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 61.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.3 0.0 0.1 0.0 0.0 0.0 LCE1F LEP6 ENSG00000240386 "Late cornified envelope 1F" Q5T754 1 152776372-152776728 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skin 1: 209.8" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 18.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 5.5;melanoma: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 6.5;hTERT-HME1: 3.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.21e-1)" "unprognostic (8.43e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 209.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 LCE2B "LEP10, SPRL1B, XP5" ENSG00000159455 "Late cornified envelope 2B" O14633 1 152686123-152687397 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 719.8" "Cell type enriched" "Detected in some" 17 "Suprabasal keratinocytes: 31.5" "Cancer enriched" "Detected in some" 5 "melanoma: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.04e-2)" "unprognostic (1.36e-1)" 0.5 0.1 0.0 0.0 0.0 0.0 42.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.1 719.8 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 31.5 0.0 0.1 0.0 0.0 0.0 LCE2C LEP11 ENSG00000187180 "Late cornified envelope 2C" Q5TA81 1 152675295-152676574 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 321.2" "Cell type enriched" "Detected in single" 35 "Suprabasal keratinocytes: 14.2" "Cancer enriched" "Detected in some" 5 "melanoma: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.47e-2)" "unprognostic (7.00e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 321.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 LCE2D "LEP12, SPRL1A" ENSG00000187223 "Late cornified envelope 2D" Q5TA82 1 152663380-152664659 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 152.1" "Group enriched" "Detected in some" 8 "Melanocytes: 1.8;Suprabasal keratinocytes: 4.7" "Group enriched" "Detected in some" 42 "head and neck cancer: 1.2;melanoma: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.94e-2)" "unprognostic (5.63e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 152.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 LCE5A "LEP18, SPRL5A" ENSG00000186207 "Late cornified envelope 5A" Q5TCM9 1 152510803-152512177 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 91.5" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 7.4" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.51e-1)" "unprognostic (7.27e-3)" "unprognostic (9.27e-2)" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 11.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 91.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 LCE6A C1orf44 ENSG00000235942 "Late cornified envelope 6A" A0A183 1 152842856-152843983 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 246.6" "Cell type enriched" "Detected in single" 8 "Suprabasal keratinocytes: 2.6" "Cancer enriched" "Detected in some" 5 "melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046376 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA046376: AB_10965998" "unprognostic (4.25e-2)" "unprognostic (8.73e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 246.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6695.7" "Group enriched" "Detected in many" 10 "Basal keratinocytes: 1529.6;Suprabasal keratinocytes: 5136.5" "Cancer enhanced" "Detected in many" "cervical cancer: 142.7;head and neck cancer: 185.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HaCaT: 3.9;OE19: 3.9" "HPA001549, CAB025100" Supported "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB025100: , HPA001549: AB_1078938" "unprognostic (4.20e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-2)" "unprognostic (3.66e-3)" "unprognostic (6.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-3)" 6.1 1.0 0.0 0.0 0.0 0.1 7.3 0.0 0.0 490.5 0.0 1.8 0.0 1.0 0.0 1463.3 0.9 0.0 2.6 0.0 0.0 2.1 3.0 2.6 0.0 0.0 0.0 1.4 2.7 0.0 2.2 0.0 0.0 5.0 0.0 0.0 167.2 0.1 10.2 6695.7 1.7 0.0 0.0 22.0 3.0 4.9 0.0 0.2 2.3 0.0 1.6 1.0 834.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1529.6 6.3 253.5 102.4 0.0 1.2 13.3 0.4 0.0 64.4 1.8 0.0 0.0 0.0 0.3 0.0 0.0 5.4 3.1 0.2 3.2 1.2 0.0 0.0 0.2 0.1 3.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 41.3 12.3 0.0 0.3 44.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 2.1 0.3 0.3 9.3 0.0 0.0 1.3 4.2 7.5 1.9 329.6 5136.5 0.0 1.6 0.4 0.1 14.0 LIPM "bA304I5.1, LIPL3" ENSG00000173239 "Lipase family member M" Q5VYY2 10 88802730-88820546 "Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 28.0" "Cell type enriched" "Detected in single" 11 "Suprabasal keratinocytes: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071276 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "Endoplasmic reticulum" "HPA071276: " "unprognostic (7.72e-2)" "unprognostic (8.49e-4)" "unprognostic (1.42e-2)" "unprognostic (2.23e-4)" "unprognostic (6.70e-3)" "unprognostic (3.01e-3)" "unprognostic (5.75e-2)" "unprognostic (6.63e-2)" "unprognostic (5.61e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.59e-2)" "unprognostic (5.93e-2)" "unprognostic (7.05e-3)" "unprognostic (4.17e-2)" "unprognostic (9.02e-2)" "unprognostic (9.70e-6)" 0.1 0.0 0.0 0.2 0.0 0.1 1.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 28.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 LY6G6C "C6orf24, G6c, NG24" ENSG00000204421 "Lymphocyte antigen 6 family member G6C" O95867 6 31718648-31721746 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "skin 1: 511.5" "Cell type enhanced" "Detected in some" "Early spermatids: 11.3;Late spermatids: 13.1;Suprabasal keratinocytes: 64.2;Syncytiotrophoblasts: 20.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.5;CACO-2: 1.0;HaCaT: 2.0;MCF7: 3.2;OE19: 1.5;SuSa: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.21e-1)" "unprognostic (3.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.85e-3)" "unprognostic (2.59e-3)" "unprognostic (1.35e-1)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (4.13e-1)" "unprognostic (1.76e-3)" "unprognostic (2.85e-1)" "unprognostic (8.80e-7)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (6.09e-2)" "unprognostic (9.38e-2)" 1.1 0.1 0.1 0.2 0.4 0.0 15.8 0.1 0.4 13.0 0.1 0.3 0.0 0.4 0.2 47.6 1.5 0.0 0.5 0.2 0.1 0.2 0.4 0.6 0.0 0.1 0.1 0.6 0.2 0.1 0.3 7.6 0.1 0.5 0.1 0.1 12.0 0.0 1.6 511.5 0.2 0.1 0.1 0.6 0.5 1.9 0.1 1.2 0.6 0.0 12.1 0.3 31.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.3 0.1 0.0 0.1 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.6 0.0 0.0 0.3 0.1 4.7 0.7 0.5 0.6 0.0 3.5 2.0 0.1 0.0 0.1 0.0 0.0 7.5 0.0 2.3 0.0 0.1 11.3 1.3 1.3 0.6 0.0 0.0 0.0 0.0 1.2 0.7 0.0 3.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 2.0 0.0 0.0 0.7 13.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 2.1 0.2 0.0 0.9 0.0 0.0 0.4 0.5 0.0 0.1 6.1 64.2 20.4 0.2 0.1 2.0 3.2 MARS2 "mtMetRS, SPAX3" ENSG00000247626 "Methionyl-tRNA synthetase 2, mitochondrial" Q96GW9 2 197705369-197708395 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 17.1;Suprabasal keratinocytes: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035589, HPA035590" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" "HPA035589: AB_10601870, HPA035590: AB_2674693" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.12e-4)" "unprognostic (2.99e-2)" "unprognostic (2.35e-2)" "unprognostic (1.53e-1)" "unprognostic (7.61e-2)" "unprognostic (1.04e-1)" "unprognostic (9.54e-2)" "unprognostic (1.86e-3)" "prognostic favorable (6.14e-5)" "unprognostic (1.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.47e-2)" "unprognostic (8.74e-2)" 3.0 4.7 1.8 4.7 2.9 3.6 4.1 3.0 3.0 1.8 1.4 5.4 4.7 1.9 1.4 4.9 2.3 2.2 4.1 2.1 2.5 4.0 5.7 2.0 6.5 2.7 2.7 1.6 5.3 4.1 0.9 2.5 3.2 2.0 5.0 1.7 3.1 1.7 4.8 3.2 3.7 2.5 2.5 4.5 3.3 1.9 2.7 3.2 3.1 6.0 6.6 4.2 2.2 4.1 6.9 8.2 7.7 13.0 7.2 3.5 14.5 5.2 4.1 9.8 7.3 21.1 6.3 43.4 7.6 3.0 5.2 12.8 27.2 11.2 10.3 11.8 15.9 26.7 9.7 18.7 6.8 39.7 12.3 3.7 14.0 6.6 11.3 2.6 6.5 12.6 31.7 15.1 5.6 11.7 20.3 18.7 13.3 16.1 20.6 20.7 8.1 30.7 11.8 12.2 13.6 6.5 6.5 17.5 11.9 10.0 7.5 13.8 5.2 8.0 6.3 6.1 15.4 10.0 8.0 35.7 6.0 23.8 7.5 0.0 2.5 0.7 4.3 4.0 5.0 2.7 3.5 3.9 4.0 3.0 5.6 6.3 0.1 8.6 1.9 2.8 6.6 3.6 1.8 2.9 3.0 3.0 2.1 2.5 2.7 2.7 3.2 2.5 2.7 4.1 0.7 0.0 1.1 0.7 5.3 17.1 6.2 2.6 9.1 1.7 3.3 1.4 1.9 0.0 1.8 3.7 0.0 1.8 2.1 3.7 5.9 2.1 2.8 0.6 1.7 2.2 0.0 7.2 1.7 1.8 1.3 1.6 3.1 0.9 4.5 1.5 1.1 7.7 2.6 0.0 1.7 1.6 0.0 2.2 4.2 0.8 1.5 0.8 5.4 2.8 1.7 1.6 0.0 1.5 2.0 1.2 2.4 0.4 2.1 3.1 1.1 4.4 1.3 2.3 0.0 2.5 3.1 3.5 2.7 7.3 18.9 0.8 3.9 4.1 5.4 4.8 MED30 "THRAP6, TRAP25" ENSG00000164758 "Mediator complex subunit 30" Q96HR3 8 117520713-117540262 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 169.9;Suprabasal keratinocytes: 152.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045767 Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA045767: AB_2679446" "unprognostic (1.15e-1)" "unprognostic (1.90e-1)" "unprognostic (3.86e-2)" "unprognostic (1.57e-2)" "unprognostic (1.46e-1)" "unprognostic (3.20e-2)" "unprognostic (2.00e-2)" "unprognostic (3.33e-2)" "unprognostic (8.41e-2)" "unprognostic (4.02e-2)" "unprognostic (1.51e-2)" "unprognostic (7.73e-2)" "prognostic unfavorable (1.70e-6)" "unprognostic (5.38e-3)" "unprognostic (2.80e-1)" "unprognostic (1.05e-1)" "unprognostic (4.62e-2)" 18.4 9.4 10.7 11.6 11.4 44.6 17.6 11.4 14.4 15.5 10.1 14.6 9.3 15.7 8.3 12.6 18.4 6.6 11.0 10.4 10.6 8.2 15.2 13.0 17.3 11.1 10.8 20.1 9.1 7.3 10.0 11.4 11.1 11.4 11.6 5.0 9.7 10.3 10.4 17.0 12.4 9.3 11.5 14.0 11.2 11.4 10.9 25.1 12.1 10.4 15.3 13.3 14.9 12.7 54.0 5.6 20.8 13.9 14.2 13.3 22.9 15.9 16.9 23.8 29.4 10.2 26.2 42.7 24.7 8.7 18.3 23.7 18.6 12.4 30.4 57.4 23.0 34.7 3.2 13.2 15.6 27.7 28.9 12.3 13.8 12.3 27.5 8.8 14.9 60.7 19.7 25.2 11.4 12.7 85.9 70.9 11.6 50.6 38.7 31.5 26.1 19.1 12.2 9.3 29.2 24.7 18.8 42.6 25.6 18.8 10.3 35.1 7.1 11.5 30.2 21.2 28.0 22.0 16.1 50.1 10.7 31.2 19.7 64.0 37.9 111.3 46.7 46.2 49.7 56.3 46.8 46.7 42.8 63.6 51.8 49.4 90.7 44.5 69.9 82.5 55.6 43.4 10.7 11.4 11.4 14.4 10.4 10.6 11.1 10.8 11.1 11.5 10.9 12.7 47.6 9.6 21.7 9.1 71.4 169.9 81.2 65.2 52.9 6.0 33.7 46.6 5.5 25.8 32.2 9.2 6.2 45.3 62.8 27.9 11.7 22.6 32.7 49.5 38.0 33.2 37.7 35.7 10.0 22.7 69.4 46.9 15.8 42.0 21.5 15.7 30.0 21.9 30.4 0.0 12.7 43.4 42.7 28.8 65.4 11.9 59.7 37.7 40.9 6.5 23.5 10.4 43.3 9.0 18.4 20.5 34.4 37.2 37.5 76.5 24.2 16.9 64.8 5.3 32.9 68.4 44.6 47.8 37.1 46.4 152.3 61.6 60.4 13.5 35.5 72.1 MT4 MTIV ENSG00000102891 "Metallothionein 4" P47944 16 56565073-56568957 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "skin 1: 124.2" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 19.7" "Group enriched" "Detected in many" 6 "cervical cancer: 6.7;endometrial cancer: 11.6" "Region enriched" "Detected in single" 8 "cerebral cortex: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (8.81e-2)" 1.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 2.1 4.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 124.2 0.0 0.0 0.0 0.0 0.0 1.6 0.1 6.2 0.0 0.0 0.0 0.0 18.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 2.1 0.1 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.8 19.7 0.0 0.0 0.0 0.0 0.0 NAB1 ENSG00000138386 "NGFI-A binding protein 1" Q13506 2 190646746-190692766 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002738 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA002738: AB_1079447" "unprognostic (1.44e-1)" "unprognostic (2.65e-2)" "unprognostic (6.02e-3)" "unprognostic (4.04e-3)" "unprognostic (9.05e-2)" "unprognostic (9.45e-2)" "unprognostic (7.12e-3)" "unprognostic (6.41e-2)" "unprognostic (2.13e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.52e-1)" "unprognostic (7.23e-3)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" 29.3 20.3 19.4 23.5 16.7 18.6 34.8 50.4 23.5 28.1 7.4 22.8 15.8 32.3 50.1 36.3 27.5 28.0 28.5 18.7 9.7 19.9 37.8 22.8 26.8 13.4 13.2 26.0 17.9 23.5 21.1 26.4 14.9 18.5 25.6 41.4 20.7 20.9 8.0 66.7 17.1 25.2 14.9 19.8 37.9 26.0 13.8 21.2 37.9 17.2 26.3 31.2 24.2 25.9 35.5 25.8 65.0 22.6 24.5 42.7 111.0 35.5 55.7 26.4 29.8 62.8 38.4 39.6 40.6 28.3 48.9 88.4 37.4 45.9 51.8 126.1 31.0 46.7 96.3 30.2 15.8 19.8 22.4 24.6 70.4 55.9 17.1 37.4 41.5 23.9 46.3 33.2 40.6 17.4 28.7 20.0 22.8 38.4 35.2 35.0 46.7 15.9 19.3 34.5 57.9 46.9 41.8 13.9 37.3 82.8 11.4 30.6 29.0 54.5 43.0 31.0 21.6 25.7 30.3 29.5 57.3 17.6 43.7 0.0 1.3 0.6 1.3 1.1 1.9 0.7 1.3 1.7 0.9 0.4 1.4 1.5 2.9 2.6 3.7 0.8 3.3 0.8 19.4 16.7 50.4 23.5 18.7 9.7 13.4 13.2 14.9 14.9 13.8 25.9 24.1 6.4 21.2 14.0 5.9 102.0 23.1 24.6 31.3 26.1 19.7 19.7 18.2 11.5 29.8 12.9 12.5 4.3 9.2 11.4 3.9 10.3 1.4 17.5 10.8 30.1 14.4 12.0 37.2 8.0 11.1 25.2 21.4 23.4 20.3 14.2 44.6 25.7 6.7 6.7 21.2 17.5 14.2 17.3 77.4 3.2 13.4 20.7 39.2 24.4 10.6 12.4 11.3 29.1 28.3 10.2 26.3 14.7 14.9 30.5 4.8 5.1 22.3 15.5 46.0 24.6 39.2 1.7 27.3 55.7 138.9 1.2 16.7 7.3 16.0 29.9 NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481124-79556075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 342.7;Late spermatids: 290.4;Suprabasal keratinocytes: 367.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.1;eosinophil: 22.7;naive CD4 T-cell: 5.6" "Group enriched" "Detected in many" 16 "granulocytes: 22.7;T-cells: 5.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" 13.9 19.2 17.0 11.4 20.9 2.6 22.7 10.0 25.2 15.5 7.0 42.7 52.7 10.1 22.5 54.4 17.1 20.1 26.0 27.1 8.1 45.9 46.3 17.7 13.0 10.1 7.3 7.0 31.8 29.6 6.4 31.9 12.3 22.7 47.0 21.7 21.4 15.6 30.9 71.3 64.3 9.1 10.6 11.7 25.9 18.1 9.2 16.0 19.3 19.9 19.6 35.6 25.2 21.5 134.6 22.6 23.2 29.4 27.7 50.3 43.6 48.5 66.9 50.1 83.0 49.9 146.1 5.6 32.6 64.0 28.5 178.2 20.5 84.9 75.3 69.7 57.1 6.2 66.5 27.1 50.5 106.2 17.8 40.4 109.3 33.4 52.7 55.8 24.1 10.4 27.5 10.0 56.8 19.3 8.7 24.1 17.1 109.7 22.7 0.5 45.7 25.2 123.1 76.7 23.3 33.4 54.9 52.4 40.0 37.8 43.8 88.2 20.4 16.0 20.4 31.1 32.8 37.6 44.2 21.1 65.6 0.5 65.6 12.1 0.0 22.7 3.2 0.0 2.7 0.2 2.8 2.6 0.0 0.6 5.6 3.1 0.1 0.8 0.0 0.2 3.2 2.4 17.0 20.9 10.0 25.2 27.1 8.1 10.1 7.3 12.3 10.6 9.2 21.5 17.5 41.7 28.9 26.4 4.4 342.7 137.0 180.6 118.4 30.9 32.7 18.8 29.4 57.2 93.2 47.8 6.2 112.6 6.9 161.0 23.5 85.6 271.2 51.5 17.2 22.0 69.4 4.2 189.0 72.2 152.7 33.2 31.1 49.8 88.2 11.5 20.7 69.2 14.4 16.8 44.2 88.1 95.6 17.0 23.5 290.4 17.4 4.0 33.8 27.2 2.7 22.8 5.2 42.3 100.3 101.7 96.7 12.8 13.8 105.6 204.3 104.6 112.6 15.5 13.1 22.2 24.0 56.5 45.1 102.2 367.7 109.7 24.9 35.2 73.3 145.5 NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 613.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 571.9;Distal enterocytes: 405.4;Horizontal cells: 588.9;Suprabasal keratinocytes: 667.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 606.9;hTERT-HME1: 1226.9;U-87 MG: 772.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" 161.2 72.9 299.1 55.9 523.6 130.0 107.6 413.5 300.2 169.4 132.8 130.0 242.2 92.9 34.3 343.1 106.4 87.8 99.8 254.5 316.6 192.4 49.6 116.6 38.7 523.2 500.0 126.1 52.8 69.1 82.2 110.8 476.8 354.3 77.8 86.0 130.8 60.0 28.2 262.6 258.1 61.9 333.7 39.4 154.0 28.1 423.1 55.1 80.5 44.6 88.1 105.5 273.8 613.9 191.6 24.0 1.7 0.8 116.3 86.8 26.0 13.7 103.0 9.8 52.5 12.5 27.6 1.5 133.0 58.0 21.9 62.4 1.7 316.8 18.0 13.3 226.8 1.9 55.6 14.7 46.3 7.0 4.6 79.2 606.9 51.2 1226.9 124.2 45.2 27.9 2.0 138.3 17.2 11.0 19.1 20.8 3.0 69.8 155.8 1.7 19.4 86.2 29.7 28.0 13.8 13.0 31.0 312.1 73.3 48.6 1.3 20.0 58.5 84.4 43.6 40.7 10.4 96.3 280.3 0.8 772.5 69.5 161.5 10.9 4.3 0.0 5.8 3.4 9.1 1.6 5.3 6.9 6.0 1.4 3.9 3.1 4.0 1.5 4.2 13.0 8.1 3.7 299.1 523.6 413.5 300.2 254.5 316.6 523.2 500.0 476.8 333.7 423.1 613.9 123.0 144.2 47.4 14.4 23.6 571.9 141.3 207.3 42.1 68.8 28.6 31.2 20.6 80.1 102.9 187.6 2.1 12.8 68.1 405.4 33.2 33.2 5.3 57.4 59.0 217.7 22.1 17.4 7.7 13.7 138.2 90.5 151.4 167.7 22.2 41.0 112.8 64.0 16.5 588.9 5.7 140.9 83.4 31.1 109.5 5.9 49.0 42.7 101.4 28.1 25.7 81.2 14.4 20.6 136.2 62.9 155.9 44.0 23.5 264.3 402.5 87.5 38.7 40.3 46.0 65.2 44.3 1.2 7.1 113.0 667.4 43.4 45.7 32.6 124.7 280.8 NIPAL4 ICHYN ENSG00000172548 "NIPA like domain containing 4" Q0D2K0 5 157460213-157474722 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" Receptor "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7;skin 1: 61.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 29.7;Basal prostatic cells: 9.8;Oligodendrocytes: 21.0;Squamous epithelial cells: 9.8;Suprabasal keratinocytes: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.0;urothelial cancer: 11.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 25 "memory B-cell: 1.6;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 37 "B-cells: 4.8" "Group enriched" "Detected in some" 8 "hTCEpi: 31.7;RT4: 108.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038259 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 28: Keratinocytes - Keratinization" "HPA038259: AB_10672510" "unprognostic (6.74e-4)" "unprognostic (9.54e-2)" "unprognostic (2.63e-2)" "unprognostic (1.49e-1)" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (3.55e-2)" "unprognostic (5.20e-2)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (1.76e-2)" "unprognostic (5.28e-9)" "unprognostic (3.12e-2)" "unprognostic (8.66e-3)" "unprognostic (1.18e-2)" "prognostic favorable (6.82e-4)" 0.4 0.0 3.5 2.0 9.7 3.4 2.2 8.5 7.1 5.9 1.1 3.7 0.3 1.2 0.1 15.1 0.1 0.5 1.5 3.9 6.2 0.0 0.0 0.7 0.4 12.4 8.7 0.0 0.0 0.0 0.5 0.6 10.5 1.5 0.6 0.1 1.9 1.4 0.2 61.2 0.9 1.1 7.6 0.2 2.5 0.1 8.0 0.4 0.3 0.0 5.8 11.5 15.1 18.7 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 0.1 1.1 0.0 0.0 0.7 0.4 0.0 6.3 0.3 2.7 0.6 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.3 31.7 0.0 1.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 108.1 0.0 0.4 0.0 0.0 0.0 8.5 1.6 0.0 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 9.7 8.5 7.1 3.9 6.2 12.4 8.7 10.5 7.6 8.0 18.7 0.0 0.0 0.5 0.0 2.4 29.7 9.8 0.6 2.2 0.6 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.7 0.3 0.0 1.1 1.8 0.0 0.0 0.0 0.0 0.0 21.0 0.1 0.0 0.0 0.3 3.8 0.0 0.0 0.1 1.1 0.0 5.2 0.3 0.0 0.1 9.8 42.1 0.0 0.2 0.0 0.0 4.4 NRARP MGC61598 ENSG00000198435 "NOTCH regulated ankyrin repeat protein" Q7Z6K4 9 137299631-137302271 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 47.9" "Cell type enhanced" "Detected in many" "Adipocytes: 75.3;Basal keratinocytes: 97.0;Langerhans cells: 97.9;Squamous epithelial cells: 101.8;Suprabasal keratinocytes: 381.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 45.1;MCF7: 23.3;NTERA-2: 31.9;OE19: 30.8;T-47d: 23.1;TIME: 31.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025729 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" Cytosol Nucleoplasm "HPA025729: AB_1854633" "unprognostic (9.92e-2)" "unprognostic (1.75e-2)" "unprognostic (1.56e-1)" "unprognostic (7.17e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-1)" "unprognostic (3.42e-2)" "unprognostic (1.89e-2)" "unprognostic (1.00e-2)" "unprognostic (6.42e-2)" "unprognostic (4.73e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.73e-6)" "unprognostic (2.85e-3)" "unprognostic (1.34e-1)" "unprognostic (4.90e-2)" "unprognostic (3.28e-3)" 8.9 1.7 7.8 7.6 7.9 1.5 6.9 8.8 7.8 6.5 4.2 47.9 22.0 4.4 1.2 22.6 3.6 12.0 12.5 7.3 10.8 6.1 2.7 7.1 1.6 11.5 12.6 2.0 16.8 2.7 7.6 10.3 10.5 9.5 30.5 1.5 3.0 2.1 2.9 26.3 17.8 3.4 9.8 4.2 8.7 10.2 14.8 2.7 4.9 6.5 4.1 10.4 13.5 6.6 4.8 1.0 8.0 8.8 0.0 0.0 2.6 0.1 0.2 0.0 0.1 6.8 3.0 0.0 10.2 0.0 0.4 45.1 13.9 0.4 0.1 0.3 20.6 1.4 2.1 7.6 0.8 2.8 4.3 0.0 2.3 0.0 0.6 0.2 11.8 0.1 11.8 0.3 0.0 23.3 0.2 6.4 31.9 30.8 6.7 8.4 1.5 17.7 1.2 0.6 4.9 8.1 1.4 2.4 0.1 1.7 23.1 5.8 31.9 0.0 0.1 0.1 1.9 0.3 0.2 3.0 0.1 5.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 7.9 8.8 7.8 7.3 10.8 11.5 12.6 10.5 9.8 14.8 6.6 75.3 0.0 0.0 33.3 17.6 97.0 5.9 20.1 15.9 0.6 24.4 39.2 4.4 5.7 14.3 0.0 0.0 0.1 9.7 22.4 0.0 0.5 17.3 35.2 4.4 21.9 10.2 0.0 2.5 1.1 0.0 2.1 19.4 43.0 0.0 0.3 8.9 0.1 0.4 0.0 0.4 20.5 8.2 0.6 97.9 5.2 0.0 18.6 17.8 9.4 0.0 6.8 0.0 2.0 0.6 0.6 28.3 0.4 3.9 6.2 5.0 0.1 3.2 2.8 6.6 4.0 32.1 0.1 0.6 101.8 381.0 0.0 6.7 3.7 23.4 6.0 NXT1 "MTR2, P15" ENSG00000132661 "Nuclear transport factor 2 like export factor 1" Q9UKK6 20 23350791-23354771 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 235.3;Suprabasal keratinocytes: 253.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 200.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047471 Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Cytosol "HPA047471: AB_2680061" "unprognostic (6.44e-2)" "unprognostic (2.89e-1)" "unprognostic (3.07e-2)" "unprognostic (1.02e-3)" "unprognostic (1.99e-1)" "unprognostic (2.57e-2)" "unprognostic (1.28e-3)" "unprognostic (5.89e-2)" "unprognostic (1.17e-1)" "unprognostic (6.89e-2)" "unprognostic (5.54e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.15e-7)" "unprognostic (2.07e-1)" "unprognostic (1.98e-1)" "unprognostic (9.11e-3)" "unprognostic (9.31e-2)" 26.4 14.2 10.4 12.4 10.4 46.8 20.6 11.0 11.7 18.7 11.0 16.0 6.9 17.8 16.7 19.6 22.8 10.1 15.7 9.9 11.0 19.8 13.7 18.9 13.7 11.1 11.1 23.9 12.5 9.6 17.9 13.0 11.3 14.9 10.1 9.4 12.8 11.6 11.6 22.7 13.8 14.9 11.2 17.6 15.2 17.6 11.2 18.3 14.4 9.5 18.3 21.5 16.9 11.1 46.3 50.6 29.9 31.4 20.7 20.0 27.9 27.7 31.0 44.3 44.5 33.7 44.2 55.0 40.3 27.7 73.0 52.8 35.6 72.6 43.3 26.5 33.2 40.5 10.4 60.4 30.9 43.6 29.5 17.9 47.6 42.8 60.4 17.5 35.7 39.5 54.7 52.6 34.7 60.1 90.7 76.4 25.2 82.3 110.9 61.9 48.4 64.7 27.0 38.5 48.4 28.4 25.4 66.7 53.3 18.2 37.5 50.1 22.7 44.6 36.9 37.7 54.1 35.9 37.2 64.0 12.6 200.8 33.9 43.6 46.7 34.5 80.2 68.7 99.2 141.5 80.4 84.3 69.5 131.4 97.9 88.3 11.5 107.9 51.1 113.5 62.1 87.8 10.4 10.4 11.0 11.7 9.9 11.0 11.1 11.1 11.3 11.2 11.2 11.1 63.4 16.0 13.1 1.0 67.0 235.3 141.0 82.9 132.1 10.1 73.1 91.4 7.6 17.2 36.1 20.2 4.2 75.4 64.7 8.2 41.1 39.7 20.3 34.0 39.3 62.1 18.7 41.9 1.5 31.2 77.1 63.7 5.6 37.8 76.2 23.5 27.5 13.4 45.3 11.8 2.2 23.9 59.0 16.6 141.2 12.8 51.6 36.9 108.5 1.9 23.9 24.5 35.0 2.5 2.8 41.3 11.0 40.3 46.0 111.3 8.3 24.1 24.0 18.3 6.6 89.5 70.5 89.6 76.4 87.4 253.5 40.2 66.7 27.8 27.9 118.1 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 PANX1 "MRS1, PX1, UNQ2529" ENSG00000110218 "Pannexin 1" Q96RD7 11 94128841-94181968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Oogenesis, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016930 Uncertain Enhanced "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA016930: AB_1854954" "unprognostic (1.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (7.02e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.09e-5)" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.26e-3)" 11.4 7.2 5.1 12.1 5.2 4.1 6.4 1.2 5.5 7.9 2.7 8.4 5.4 8.5 5.2 7.9 5.2 11.5 9.9 5.0 7.1 6.9 16.8 10.2 6.4 2.1 2.9 7.1 7.4 4.4 4.7 9.7 3.3 7.7 7.2 3.1 6.0 7.0 20.8 8.3 5.8 12.8 2.8 5.8 7.4 9.9 4.9 8.1 8.7 10.8 7.0 21.9 6.5 2.7 24.6 10.2 26.2 16.0 23.9 32.3 17.1 29.8 63.0 25.1 30.7 26.2 37.6 7.8 27.3 30.5 46.1 50.5 20.9 49.2 25.2 33.6 10.9 36.0 10.2 13.5 23.1 18.7 31.0 25.7 33.9 32.8 29.2 16.1 21.2 20.1 23.8 27.5 28.3 7.8 31.3 4.4 21.0 19.7 18.2 36.7 35.0 9.7 16.3 24.0 11.0 31.9 20.9 11.9 14.4 13.3 25.2 9.5 15.4 49.5 25.5 16.4 29.9 4.5 18.2 12.6 20.6 19.0 32.2 3.2 4.0 0.3 2.1 2.2 2.4 1.3 1.7 2.3 2.7 1.2 1.6 1.7 0.2 2.6 1.4 0.4 2.9 3.2 5.1 5.2 1.2 5.5 5.0 7.1 2.1 2.9 3.3 2.8 4.9 2.7 3.8 0.0 8.7 4.6 6.6 102.0 12.3 14.9 13.6 1.3 4.5 2.0 4.7 4.3 4.7 1.8 0.0 12.8 5.3 4.7 0.0 15.7 5.3 9.1 13.0 6.8 2.4 5.2 8.9 18.2 32.4 17.5 7.1 13.9 9.5 4.0 2.2 8.1 20.5 0.0 15.4 4.1 0.0 3.1 21.6 3.9 4.4 11.5 17.8 8.4 3.7 1.1 1.0 9.5 5.8 26.1 3.4 3.8 7.4 10.2 2.6 2.1 6.2 1.1 0.0 16.9 10.6 1.7 8.2 8.3 72.2 23.8 6.6 10.1 4.2 12.7 PHF23 "FLJ16355, MGC2941" ENSG00000040633 "PHD finger protein 23" Q9BUL5 17 7235029-7239722 "Disease related genes, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052410 Approved Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA052410: AB_2681822" "unprognostic (1.76e-2)" "unprognostic (6.12e-2)" "unprognostic (4.72e-2)" "unprognostic (6.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.96e-2)" "unprognostic (2.41e-3)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.19e-1)" "unprognostic (2.67e-3)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "unprognostic (4.40e-1)" "unprognostic (1.61e-1)" "unprognostic (3.48e-2)" 22.0 39.6 21.3 24.5 21.0 10.1 19.1 21.6 25.1 22.3 20.7 24.2 22.8 23.6 23.3 35.3 20.2 20.2 18.0 22.7 23.1 22.5 26.3 18.3 30.4 25.4 30.3 19.0 17.9 24.3 20.8 23.0 25.1 24.0 17.7 15.2 19.1 22.8 22.6 19.3 21.4 22.9 21.8 28.4 19.7 24.8 23.1 36.7 24.3 21.9 34.2 29.1 23.3 22.9 49.6 78.1 85.2 56.0 54.4 54.7 33.4 65.8 72.2 78.5 66.7 42.5 34.2 72.5 39.7 71.2 55.4 46.6 81.1 54.1 64.6 73.7 67.4 54.6 51.5 47.8 87.5 26.4 82.7 75.9 51.5 68.4 45.6 82.3 75.6 34.8 61.1 17.4 92.7 37.9 45.7 53.5 80.7 35.7 34.3 61.5 41.5 35.4 83.9 27.4 28.0 89.0 47.0 37.9 75.2 50.9 46.0 30.7 69.5 69.0 47.9 41.2 82.8 32.0 35.2 37.6 62.0 42.9 60.6 23.1 8.2 15.5 16.2 6.6 13.9 12.0 12.3 17.9 9.3 15.6 10.0 12.5 15.9 10.7 9.5 16.7 11.2 7.9 21.3 21.0 21.6 25.1 22.7 23.1 25.4 30.3 25.1 21.8 23.1 22.9 22.3 6.4 9.2 2.0 21.9 84.1 22.7 21.6 56.9 13.6 36.5 17.7 18.7 15.7 17.2 22.0 6.2 32.1 31.2 24.0 39.2 39.2 19.8 20.2 25.7 26.0 18.6 33.6 3.7 21.5 21.0 20.0 8.6 22.1 17.7 15.2 17.5 13.8 37.0 16.8 2.8 18.5 26.4 20.9 40.3 24.8 24.8 20.8 33.8 4.7 37.3 14.5 35.0 3.5 2.5 35.1 26.0 17.3 23.7 28.9 16.6 30.1 11.4 11.0 39.5 14.8 29.1 30.9 22.4 39.2 83.3 76.8 21.3 30.5 16.5 27.1 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 12.9;Basal keratinocytes: 18.1;Suprabasal keratinocytes: 44.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041105, HPA072562" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Cytosol" "HPA041105: AB_2677300, HPA072562: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 18.1 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 5.1 0.5 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 5.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 44.9 0.0 0.1 0.0 0.2 0.7 PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 75.5;skeletal muscle: 66.5;skin 1: 97.2;thyroid gland: 58.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 280.2;Cardiomyocytes: 79.5;Skeletal myocytes: 80.9;Suprabasal keratinocytes: 336.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 40.7;HBEC3-KT: 86.1;HEK 293: 36.2;hTCEpi: 103.0;hTERT-HME1: 41.1;RPTEC TERT1: 35.5;SK-BR-3: 37.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB044667: , HPA047907: " "unprognostic (1.81e-3)" "unprognostic (7.65e-2)" "unprognostic (4.25e-3)" "unprognostic (6.92e-2)" "unprognostic (3.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.81e-3)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (5.13e-2)" "unprognostic (4.50e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (7.49e-3)" "unprognostic (6.77e-2)" 0.4 0.2 5.1 1.4 6.6 0.2 6.0 5.9 8.0 10.2 6.0 12.5 10.4 1.4 0.9 18.4 16.0 0.1 75.5 7.8 5.0 9.5 0.0 12.3 0.3 5.6 5.4 0.1 0.7 5.1 1.7 3.4 5.6 1.3 8.6 0.6 3.2 0.2 66.5 97.2 2.7 0.9 4.4 0.1 0.8 6.7 5.0 0.5 58.7 8.5 5.8 0.5 22.0 5.0 27.9 0.1 11.7 0.1 0.1 0.6 0.0 3.7 0.0 0.0 0.1 1.3 3.8 0.7 8.0 5.3 1.8 40.7 6.1 86.1 0.0 0.0 36.2 0.3 0.0 0.0 0.0 0.0 1.1 0.0 103.0 0.2 41.1 0.0 0.0 0.5 23.6 0.0 0.0 3.8 0.0 0.0 0.4 0.0 0.2 0.7 0.0 0.0 35.5 1.5 6.2 0.0 0.6 37.7 2.2 0.7 0.2 1.9 0.0 0.1 20.4 32.5 9.5 0.0 0.0 0.0 14.2 16.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.6 5.9 8.0 7.8 5.0 5.6 5.4 5.6 4.4 5.0 5.0 0.3 19.2 41.1 1.3 0.5 280.2 17.9 19.6 12.0 1.1 6.5 4.3 79.5 0.0 17.1 14.7 0.0 0.1 0.4 24.5 1.9 3.8 0.2 37.9 0.6 3.0 28.2 0.0 28.0 0.2 0.1 6.7 0.0 5.1 1.3 4.1 0.0 0.0 3.0 1.7 13.3 3.1 14.2 0.0 19.7 1.6 0.0 0.6 30.2 2.8 1.1 0.0 0.0 37.2 2.5 12.8 41.5 0.4 0.0 16.6 5.0 38.6 61.5 0.5 0.0 80.9 4.3 0.5 1.8 14.7 336.6 1.9 1.4 0.5 8.7 1.9 SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1056.2;skin 1: 2444.7;vagina: 756.5" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 1017.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.2;ASC TERT1: 107.5;HSkMC: 146.1;U-2197: 51.6;U-87 MG: 119.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" NA NA 89000000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" 2.9 0.6 0.5 0.1 3.9 0.7 94.3 0.4 1.3 465.7 0.3 1.0 0.0 0.5 0.0 1056.2 0.2 0.3 1.4 0.5 0.4 0.4 1.7 0.9 0.0 0.5 0.4 0.7 1.5 0.0 0.9 0.3 0.5 0.5 0.0 0.0 351.8 0.0 13.1 2444.7 0.7 0.2 0.4 0.5 1.1 1.0 0.5 6.5 0.7 0.0 168.9 1.1 756.5 0.4 0.1 0.1 0.0 0.1 62.2 107.5 0.1 5.1 7.2 2.4 0.9 0.0 0.1 0.1 1.2 4.8 1.7 0.3 0.0 1.8 1.0 0.1 0.2 0.0 0.1 0.0 0.6 0.0 0.1 146.1 8.2 30.0 7.1 2.1 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.4 0.3 0.2 0.0 0.4 18.4 3.8 51.6 1.4 0.5 0.3 0.0 119.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.9 0.4 1.3 0.5 0.4 0.5 0.4 0.5 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 89.3 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.4 0.8 1.8 0.0 0.0 0.2 0.6 0.2 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 4.0 0.0 0.2 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 1.0 0.2 0.2 13.4 1017.6 0.3 0.7 0.0 0.0 0.4 SDR9C7 "RDHS, SDR-O" ENSG00000170426 "Short chain dehydrogenase/reductase family 9C member 7" Q8NEX9 12 56923133-56934408 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.5;skin 1: 58.5;vagina: 21.3" "Group enriched" "Detected in some" 5 "Early spermatids: 1.2;Suprabasal keratinocytes: 4.0" "Group enriched" "Detected in some" 6 "cervical cancer: 3.0;head and neck cancer: 11.0;melanoma: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (6.75e-2)" "unprognostic (1.42e-1)" "unprognostic (7.90e-5)" "unprognostic (7.93e-2)" "unprognostic (4.20e-3)" "unprognostic (1.26e-1)" "unprognostic (4.74e-2)" "unprognostic (9.31e-2)" "unprognostic (3.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.27e-1)" "unprognostic (1.74e-3)" 0.1 0.0 0.1 0.0 0.1 0.0 2.6 0.2 0.3 11.3 0.0 0.3 0.0 0.4 0.0 14.5 0.2 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.1 0.0 0.8 58.5 0.1 0.0 0.0 0.2 0.1 0.8 0.0 0.5 0.0 0.0 7.5 0.2 21.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.0 0.0 0.0 0.0 0.0 0.0 SERPINA12 "OL-64, Vaspin" ENSG00000165953 "Serpin family A member 12" Q8IW75 14 94487274-94517844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 396.4" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 20.9" "Group enriched" "Detected in some" 5 "liver cancer: 1.8;melanoma: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "Hep G2: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 6500000 "Cluster 61: Skin - Cornification" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.82e-3)" "unprognostic (6.44e-2)" "unprognostic (3.25e-1)" "unprognostic (1.00e-2)" "unprognostic (5.98e-2)" "unprognostic (2.97e-2)" "unprognostic (7.64e-3)" "unprognostic (6.67e-2)" 0.3 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 396.4 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.9;Suprabasal keratinocytes: 1053.6;Syncytiotrophoblasts: 439.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cell line enhanced" "Detected in many" "GAMG: 282.7;HaCaT: 699.1;U-138 MG: 807.0;U-2197: 1243.9" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" 21.0 0.3 0.0 8.6 0.0 36.5 8.7 0.0 1.3 21.0 0.0 0.5 0.1 0.7 0.0 239.1 8.4 0.7 1.0 0.0 0.2 0.2 0.3 2.8 0.0 0.0 0.1 0.3 1.1 0.2 0.1 50.1 0.0 0.2 0.0 0.0 31.2 0.0 0.3 89.2 0.1 1.7 0.0 0.3 0.8 0.0 1.1 2.6 0.1 0.2 81.2 6.6 45.4 0.0 1.4 0.0 0.0 0.8 1.3 0.6 0.2 169.2 179.2 6.0 13.1 0.9 0.4 0.2 0.0 6.1 282.7 699.1 0.0 143.7 118.6 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.5 1.5 13.9 81.7 37.0 1.8 0.6 0.0 0.6 0.4 2.8 0.0 0.2 0.4 0.3 0.2 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 1.1 0.0 0.6 0.7 15.7 13.9 807.0 0.4 1243.9 0.0 0.2 0.1 0.0 21.6 1.8 96.7 22.0 4.9 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.5 0.0 0.2 2243.9 4.1 82.1 0.0 0.0 0.6 0.1 0.7 0.0 153.4 0.0 0.0 6.2 0.1 0.0 0.0 92.6 0.0 0.1 0.1 5.5 0.0 0.0 0.0 7.1 1.7 11.0 0.0 0.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 26.4 2.9 86.4 0.0 0.0 73.1 94.3 0.0 3.9 0.0 0.0 0.0 0.0 167.2 0.0 0.0 1.0 18.9 0.0 0.0 94.5 0.0 0.0 0.3 14.8 0.0 0.0 94.7 1053.6 439.3 2.5 0.0 0.0 52.0 SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2461.5;skin 1: 1219.1;vagina: 692.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7750.0;Basal prostatic cells: 2119.7;Squamous epithelial cells: 3587.1;Suprabasal keratinocytes: 10714.0;Urothelial cells: 2780.0" "Cancer enhanced" "Detected in all" "cervical cancer: 1510.8;head and neck cancer: 2526.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cell line enhanced" "Detected in many" "A-431: 770.8;HaCaT: 1181.6;HBEC3-KT: 1819.0;hTCEpi: 1196.7" "Low region specificity" "Detected in many" "CAB006268, HPA011105, CAB040552" Enhanced Supported Cytosol "Secreted in other tissues" NA Yes 29000000 "Cluster 34: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB006268: AB_425459, CAB040552: , HPA011105: AB_1844339" "unprognostic (5.70e-2)" "unprognostic (1.26e-1)" "unprognostic (8.37e-2)" "prognostic favorable (1.92e-4)" "unprognostic (1.26e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (1.71e-2)" "unprognostic (2.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (7.45e-6)" "unprognostic (7.90e-3)" "unprognostic (3.25e-1)" "unprognostic (8.12e-2)" "unprognostic (2.06e-2)" 3.1 0.8 1.9 11.6 1.8 2.0 29.1 1.8 9.5 350.2 0.4 95.4 48.8 8.0 0.7 2461.5 2.2 21.4 1.3 1.9 1.6 16.0 3.7 56.1 0.2 9.0 4.4 0.9 2.2 0.1 2.7 1.6 4.3 77.2 32.5 0.6 332.8 3.2 5.0 1219.1 40.8 3.3 1.2 0.9 66.6 0.7 5.2 22.1 2.0 0.1 147.9 167.6 692.0 2.3 770.8 126.9 0.1 1.1 0.3 0.1 37.2 0.5 0.0 0.1 0.3 46.6 393.6 6.7 32.2 0.2 0.6 1181.6 0.3 1819.0 0.0 183.4 5.4 0.9 119.6 138.4 0.1 0.4 1.4 0.4 1196.7 0.6 310.1 0.2 0.2 0.7 1.8 4.5 0.1 163.8 0.7 0.3 2.3 132.6 208.7 0.5 0.4 43.1 281.3 173.9 0.7 0.7 181.2 31.9 1.8 2.9 83.6 1.5 0.5 0.5 337.2 0.3 4.9 1.0 5.8 3.8 1.5 0.7 0.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 1.8 1.8 9.5 1.9 1.6 9.0 4.4 4.3 1.2 5.2 2.3 1.6 179.5 162.2 0.0 5.0 7750.0 2119.7 1374.7 1714.2 0.0 72.6 119.9 0.8 24.3 285.6 16.5 0.0 18.6 0.7 972.0 3.9 48.8 0.0 138.0 20.1 45.3 67.4 0.0 0.0 76.2 59.9 46.2 221.2 251.8 32.3 0.0 0.4 4.5 1.9 0.0 0.1 140.7 114.0 0.6 479.7 0.0 0.0 9.7 533.6 0.0 1.0 0.0 0.0 0.0 0.1 524.8 933.0 0.0 21.2 1030.2 318.5 0.6 158.2 0.0 0.0 0.7 55.2 0.0 0.6 3587.1 10714.0 6.0 23.4 0.1 292.4 2780.0 SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427131 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 88.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 302.0;Basal respiratory cells: 123.5;Langerhans cells: 141.9;Suprabasal keratinocytes: 422.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 35.3;HeLa: 63.1;hTCEpi: 45.4;LHCN-M2: 45.5;U-266/84: 37.7" "Low region specificity" "Detected in all" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Vesicles "CAB023801: , HPA038211: AB_2675894, HPA078064: " "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (3.31e-3)" "unprognostic (3.00e-1)" "unprognostic (5.02e-2)" "unprognostic (7.97e-3)" "unprognostic (1.51e-1)" "unprognostic (7.30e-3)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-1)" "unprognostic (3.89e-1)" "unprognostic (9.94e-3)" "unprognostic (3.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.82e-1)" 24.5 8.3 0.7 6.2 0.4 10.5 19.5 0.5 1.8 17.5 0.8 7.0 0.4 4.4 0.0 18.5 18.6 15.1 16.0 0.3 1.1 5.1 20.9 12.7 4.3 1.0 1.0 26.9 11.8 5.9 12.5 12.5 0.8 9.2 0.7 8.5 12.1 13.3 13.0 88.0 5.4 5.3 0.0 7.2 12.2 3.0 0.7 11.0 6.2 1.3 4.6 16.9 14.4 0.5 1.2 3.4 4.3 0.1 0.3 1.6 1.7 2.0 0.7 3.5 2.7 5.1 0.1 5.4 1.5 0.4 19.8 23.6 3.5 35.3 2.0 0.3 1.1 1.6 63.1 2.0 4.8 1.7 0.2 2.1 45.4 0.9 10.7 20.7 0.7 0.1 0.2 0.2 45.5 0.3 0.9 3.9 1.9 0.0 3.4 0.1 0.8 5.7 4.0 13.3 0.1 0.0 24.2 4.0 0.8 0.7 2.3 0.6 8.1 0.9 4.2 0.4 0.1 9.5 37.7 1.0 10.0 4.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.5 1.8 0.3 1.1 1.0 1.0 0.8 0.0 0.7 0.5 23.7 28.9 77.3 0.0 18.4 302.0 0.8 123.5 26.7 0.3 8.6 6.3 11.7 7.2 68.4 12.9 0.0 0.8 13.4 16.4 0.0 3.2 0.0 23.2 4.8 18.4 27.6 0.0 0.0 2.1 1.3 11.1 15.3 29.1 19.6 2.3 4.2 7.7 1.7 0.0 0.0 16.5 85.5 3.8 141.9 0.1 0.0 10.1 96.0 0.0 1.6 1.3 0.0 0.0 0.0 7.3 24.3 0.0 36.3 0.5 23.8 0.2 50.7 0.2 0.0 2.4 27.4 0.1 0.4 35.1 422.7 2.5 16.4 0.8 20.3 1.2 THEM5 FLJ37964 ENSG00000196407 "Thioesterase superfamily member 5" Q8N1Q8 1 151847101-151853712 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "skin 1: 158.5" "Cell type enriched" "Detected in some" 18 "Suprabasal keratinocytes: 34.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 4.0;hippocampal formation: 3.0;white matter: 1.0" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Cell line enriched" "Detected in some" 7 "HDLM-2: 57.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "basal ganglia: 13.8" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.41e-2)" "unprognostic (2.58e-3)" "unprognostic (9.55e-3)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "unprognostic (1.83e-1)" "unprognostic (7.86e-3)" "unprognostic (3.07e-3)" "unprognostic (9.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.34e-2)" "unprognostic (1.62e-2)" 0.3 1.9 2.1 2.0 0.3 0.5 4.2 0.0 4.0 1.6 0.5 0.4 1.4 0.5 0.0 6.5 0.7 3.1 1.9 3.0 0.0 1.1 0.6 1.3 6.3 0.3 0.0 0.2 1.3 0.0 0.5 0.5 0.2 0.4 0.0 0.7 3.1 0.0 1.3 158.5 0.8 0.0 0.0 1.0 1.9 1.2 0.6 0.1 1.0 0.0 0.3 1.2 3.2 1.0 6.6 0.0 0.1 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 2.3 0.0 0.0 0.0 57.6 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.3 0.0 1.7 0.2 0.0 7.1 1.2 0.6 0.0 0.2 0.7 0.0 0.0 0.4 0.1 8.6 2.1 1.1 1.4 1.4 2.4 0.0 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.7 0.1 1.7 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.9 1.7 2.1 0.3 0.0 4.0 3.0 0.0 0.3 0.0 0.2 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.8 34.7 1.1 0.0 0.0 0.0 0.0 TIMM8A "DDP, DFN1, MTS" ENSG00000126953 "Translocase of inner mitochondrial membrane 8A" O60220 X 101345661-101348742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Deafness, Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 102.2;Hepatocytes: 68.3;Suprabasal keratinocytes: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 217.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003628 Supported Supported Mitochondria NA NA 59000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" Mitochondria "HPA003628: AB_1080284" "prognostic unfavorable (7.89e-5)" "unprognostic (1.36e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (8.87e-5)" "unprognostic (2.06e-1)" "unprognostic (9.28e-3)" "unprognostic (5.14e-3)" "unprognostic (8.32e-2)" "unprognostic (1.90e-2)" "unprognostic (1.86e-3)" "unprognostic (6.41e-2)" "unprognostic (8.57e-3)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (7.75e-2)" "unprognostic (1.70e-1)" "unprognostic (3.86e-2)" 5.1 5.6 4.3 6.5 4.4 6.9 7.6 5.1 5.2 4.4 4.8 7.2 6.6 4.2 4.7 7.0 5.6 3.6 10.9 4.5 5.3 9.2 25.3 3.1 8.2 4.5 5.5 5.9 5.2 6.7 1.9 6.3 4.5 6.5 7.5 5.0 6.0 3.7 10.0 6.5 6.3 4.8 5.0 4.5 4.2 3.2 5.2 6.8 6.5 14.0 8.7 6.5 3.1 4.3 31.5 30.0 17.1 33.8 13.3 15.0 20.3 23.5 11.4 20.0 40.6 26.4 21.3 38.0 29.7 17.8 36.5 27.7 46.2 24.5 33.3 17.7 29.9 62.8 44.7 46.5 12.7 39.9 217.8 15.0 21.5 30.0 18.8 9.6 19.7 15.9 51.0 40.8 26.8 50.7 18.3 39.1 55.3 46.4 49.3 30.2 31.1 44.9 18.3 21.1 22.7 20.9 28.6 22.8 22.5 18.8 19.1 19.3 14.2 27.5 31.5 40.6 26.1 18.7 50.8 45.9 14.6 53.8 22.2 1.2 3.8 0.2 4.9 5.8 7.0 12.1 6.8 7.2 4.6 11.9 10.3 8.4 0.4 5.2 3.1 11.7 3.8 4.3 4.3 4.4 5.1 5.2 4.5 5.3 4.5 5.5 4.5 5.0 5.2 4.3 7.0 3.2 4.4 1.3 10.7 102.2 39.6 27.6 31.9 7.6 11.2 16.8 25.8 5.7 14.1 11.0 6.2 38.4 8.7 7.5 39.2 13.5 0.7 9.0 10.8 10.2 8.4 27.4 2.8 10.9 47.6 13.0 7.1 7.3 16.5 9.3 5.3 68.3 21.1 3.3 2.8 8.6 22.4 7.2 13.9 0.5 6.5 7.5 14.2 1.9 5.0 5.4 3.1 1.0 0.7 15.4 6.7 2.6 13.8 36.2 8.0 39.9 9.1 8.5 0.0 9.6 16.7 2.9 10.9 27.7 88.5 36.7 6.9 12.4 18.0 27.8 TLE3 "ESG, ESG3, GRG3, HsT18976, KIAA1547" ENSG00000140332 "TLE family member 3, transcriptional corepressor" Q04726 15 70047790-70098176 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.1" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 132.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 49.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 49.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054116 Approved Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA054116: AB_2682386" "unprognostic (5.57e-2)" "prognostic favorable (2.09e-5)" "unprognostic (5.18e-2)" "unprognostic (5.13e-2)" "unprognostic (1.15e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (5.53e-2)" "unprognostic (6.74e-2)" "unprognostic (3.11e-2)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (4.90e-2)" "unprognostic (2.43e-1)" "unprognostic (6.71e-2)" "unprognostic (6.29e-2)" "unprognostic (2.74e-1)" 16.1 6.4 9.2 18.3 11.5 65.1 15.2 10.7 10.9 17.4 2.9 20.6 17.3 10.8 3.0 31.1 10.1 5.8 9.9 12.3 15.3 16.4 13.3 20.3 17.7 15.1 13.9 14.0 14.9 5.8 10.3 12.6 11.8 23.2 6.4 4.9 19.1 10.1 8.3 29.4 21.8 6.9 13.4 23.1 15.7 22.1 15.1 13.5 13.5 2.9 18.9 9.8 19.4 12.2 7.8 24.2 13.3 23.6 12.1 9.9 80.3 1.5 4.1 3.1 2.5 34.0 22.8 22.0 32.8 2.1 4.8 14.3 32.3 11.5 1.6 30.9 45.9 36.9 50.8 6.6 11.5 11.4 51.1 20.5 6.3 9.1 8.2 19.7 15.5 47.9 26.1 96.0 4.5 20.9 41.2 28.3 14.2 7.4 24.9 36.8 13.6 24.7 7.1 41.7 19.5 28.7 66.2 29.7 28.7 14.5 33.6 24.9 11.7 9.5 18.7 29.6 16.4 84.6 57.2 35.3 13.3 37.3 25.1 2.6 4.5 2.5 1.9 4.8 1.8 9.9 2.6 2.5 2.9 4.9 2.5 3.3 49.1 2.8 5.2 8.7 1.6 1.7 9.2 11.5 10.7 10.9 12.3 15.3 15.1 13.9 11.8 13.4 15.1 12.2 27.5 12.8 27.7 16.0 49.2 115.1 47.8 19.5 59.2 19.9 45.5 28.4 8.1 4.3 18.9 62.5 31.3 25.3 38.2 55.2 7.9 11.6 45.5 17.2 5.0 27.6 28.8 15.2 6.1 5.6 64.4 25.0 17.9 32.1 53.2 25.5 23.9 21.5 37.3 0.0 5.0 30.3 10.2 41.5 78.2 76.9 14.0 51.5 35.6 13.1 35.8 32.6 1.0 9.5 0.4 11.0 31.7 18.4 47.2 39.9 41.0 13.2 8.1 4.4 0.0 39.8 24.7 5.8 28.0 67.7 132.8 82.4 37.6 0.7 43.9 31.5 TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 55.3;skin 1: 107.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.2;Microglial cells: 71.2;Respiratory ciliated cells: 62.4;Suprabasal keratinocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.5;BJ hTERT+: 73.2;fHDF/TERT166: 55.9;Hep G2: 83.0;SK-MEL-30: 128.4;WM-115: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved Nucleoplasm,Mitochondria No No "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 28: Keratinocytes - Keratinization" Mitochondria Nucleoplasm "HPA010135: AB_1079797" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.86e-3)" "unprognostic (2.01e-2)" "prognostic favorable (3.87e-4)" "unprognostic (3.74e-1)" "unprognostic (5.47e-2)" "unprognostic (4.41e-2)" "unprognostic (6.56e-2)" "prognostic favorable (9.13e-7)" "unprognostic (3.44e-2)" "unprognostic (6.05e-2)" "unprognostic (3.25e-3)" "unprognostic (5.38e-3)" 1.8 2.9 1.8 0.9 1.7 1.7 9.9 1.8 1.9 7.0 4.2 2.4 1.8 8.6 13.4 9.4 30.5 3.4 22.1 2.0 2.5 15.7 1.1 17.2 0.7 3.3 3.2 2.7 2.8 0.9 8.5 8.4 2.6 27.4 1.9 4.7 55.3 7.6 2.4 107.5 1.3 3.0 3.1 5.1 5.4 2.2 2.7 6.7 3.4 2.1 1.8 4.5 4.8 2.5 0.1 3.3 3.2 0.0 4.7 46.5 3.5 3.7 73.2 2.0 2.8 23.6 0.1 0.0 0.0 55.9 0.5 0.1 3.3 2.9 3.6 0.0 2.9 0.6 2.4 83.0 2.2 0.2 0.9 22.5 0.7 23.1 0.3 1.5 0.1 0.0 0.1 0.0 13.2 1.1 0.0 0.1 2.3 29.7 5.1 0.0 13.6 0.0 8.4 0.4 30.9 4.9 0.1 0.0 128.4 3.4 0.0 0.3 0.0 11.5 0.5 0.1 3.5 0.0 0.1 0.0 4.5 0.1 76.2 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 1.8 1.7 1.8 1.9 2.0 2.5 3.3 3.2 2.6 3.1 2.7 2.5 3.1 0.0 20.8 1.0 0.2 62.2 3.0 2.0 23.9 0.8 6.3 2.9 23.4 2.8 9.3 9.2 8.4 0.1 0.3 0.1 0.0 11.1 1.7 10.4 4.4 5.1 0.0 0.0 6.9 1.0 0.0 14.4 2.6 3.9 1.3 0.5 0.0 0.5 0.1 0.0 6.7 0.0 6.1 0.0 8.5 1.0 11.5 0.2 14.2 71.2 0.0 3.3 0.0 12.5 1.1 11.3 0.0 13.9 0.0 13.3 0.0 20.9 62.4 3.3 0.0 3.2 4.9 1.5 2.3 8.3 80.3 0.0 0.6 3.5 0.0 0.6 UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 210.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 286.0;Late spermatids: 248.3;Suprabasal keratinocytes: 239.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" "HPA045681: AB_2679417, HPA050551: AB_2681171" "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" 21.0 19.1 15.8 25.4 21.4 31.5 20.1 21.0 24.3 25.2 11.6 39.7 22.5 22.7 14.7 52.2 16.3 16.0 37.9 16.1 18.7 27.0 30.3 15.6 38.8 21.5 19.2 15.6 18.4 21.5 9.7 18.9 21.7 22.6 24.2 17.5 21.0 20.8 210.2 28.0 23.6 27.2 20.3 20.7 21.8 23.2 21.0 24.9 16.1 84.1 46.4 24.5 32.1 26.5 54.5 57.8 52.7 38.9 42.2 44.3 74.9 51.7 41.4 48.2 42.1 40.0 27.0 84.5 52.8 51.2 39.4 57.2 66.3 48.1 77.2 44.8 53.9 31.7 28.6 45.9 41.3 46.5 57.4 38.0 70.3 45.8 66.1 33.8 65.6 55.8 56.5 88.9 40.1 24.3 59.4 42.5 58.2 40.1 29.6 76.1 27.9 78.1 56.4 35.1 22.7 42.3 48.9 41.8 41.6 77.4 41.1 29.9 49.6 48.1 36.8 57.0 58.7 34.3 43.8 118.9 36.9 42.8 37.7 13.3 15.8 39.0 22.2 16.8 29.9 34.1 28.3 29.1 20.2 24.4 28.3 28.9 28.1 32.5 18.6 14.8 28.9 21.8 15.8 21.4 21.0 24.3 16.1 18.7 21.5 19.2 21.7 20.3 21.0 26.5 28.3 22.4 14.4 31.3 70.6 286.0 36.5 47.8 111.5 18.8 47.0 31.0 67.6 27.1 32.2 25.8 6.2 47.0 47.8 41.4 82.2 30.9 139.5 36.7 25.7 35.5 38.4 26.5 47.9 26.7 59.6 31.1 32.6 39.9 21.0 13.9 31.1 62.3 48.1 15.2 46.3 38.3 44.7 36.5 81.1 248.3 19.6 35.7 67.6 30.9 43.1 28.7 36.0 36.2 84.4 43.0 30.4 21.1 154.3 65.7 40.4 75.6 35.4 17.1 6.6 25.9 43.5 70.8 50.8 85.3 239.7 66.8 58.2 13.8 30.1 54.0 WDR47 KIAA0893 ENSG00000085433 "WD repeat domain 47" O94967 1 108970214-109042113 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 93.6;Suprabasal keratinocytes: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027287, HPA027289" Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" Nucleoplasm "HPA027287: AB_10599416, HPA027289: AB_10601862" "unprognostic (8.55e-2)" "unprognostic (3.36e-2)" "unprognostic (7.51e-2)" "unprognostic (2.44e-1)" "unprognostic (4.90e-1)" "prognostic favorable (9.86e-4)" "unprognostic (4.05e-3)" "unprognostic (2.83e-2)" "unprognostic (2.87e-1)" "unprognostic (3.67e-2)" "unprognostic (2.71e-2)" "unprognostic (1.93e-1)" "unprognostic (8.39e-3)" "unprognostic (7.90e-3)" "unprognostic (9.23e-2)" "unprognostic (2.73e-2)" "unprognostic (8.09e-2)" 7.8 7.1 22.6 5.5 26.6 12.2 6.3 14.1 27.3 8.8 1.5 8.0 3.7 9.3 5.7 14.4 8.5 7.3 8.1 27.7 17.9 7.6 3.5 7.0 5.6 13.4 11.0 7.5 5.9 9.2 5.3 6.5 14.6 7.3 5.3 37.0 5.8 7.0 17.0 22.9 4.5 10.2 10.9 5.7 6.0 22.7 16.7 7.7 6.2 15.3 7.5 7.5 8.9 19.5 15.6 4.7 8.8 10.9 17.0 14.8 4.7 17.4 10.7 11.4 12.7 4.6 2.3 7.0 9.0 16.7 8.4 17.1 12.5 7.6 15.0 13.1 7.0 5.8 9.9 5.3 9.7 9.2 8.3 9.2 12.4 17.9 8.5 13.8 13.7 8.1 3.5 9.5 19.4 9.3 8.9 7.2 3.7 5.0 9.1 12.5 22.3 3.9 19.0 13.3 15.3 14.0 15.2 8.1 12.5 9.4 3.7 9.3 23.5 15.1 7.0 26.7 14.5 6.1 5.4 5.5 17.6 9.0 23.0 18.0 5.4 7.1 3.3 5.7 3.1 2.4 3.1 3.5 5.8 3.4 2.8 2.5 22.0 2.7 5.9 6.3 5.5 2.6 22.6 26.6 14.1 27.3 27.7 17.9 13.4 11.0 14.6 10.9 16.7 19.5 16.5 12.8 6.5 33.3 13.8 93.6 5.1 7.7 62.0 15.3 11.1 12.6 18.9 10.0 8.0 7.3 45.9 2.4 25.1 2.7 5.9 3.5 33.2 20.5 9.3 12.1 3.0 1.7 46.2 0.9 2.1 10.7 8.2 10.4 2.5 5.6 7.1 2.0 4.4 11.8 39.1 1.0 4.1 5.5 28.4 41.4 8.4 13.9 24.9 19.7 6.3 13.2 8.2 15.1 26.5 3.9 0.9 15.1 14.9 2.4 2.4 5.5 18.9 32.3 6.6 13.5 16.5 32.2 28.9 52.1 104.4 4.9 18.9 3.3 2.1 4.1 WFDC5 "dJ211D12.5, WAP1" ENSG00000175121 "WAP four-disulfide core domain 5" Q8TCV5 20 45109452-45115172 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 393.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 55.8;Early spermatids: 17.6;Late spermatids: 10.4;Suprabasal keratinocytes: 43.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.32e-1)" "unprognostic (3.22e-2)" "unprognostic (3.05e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.32e-5)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.96e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.1 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.6 1.5 1.2 393.9 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.6 0.0 0.0 13.3 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 55.8 0.4 2.5 0.6 0.0 0.1 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.1 0.0 0.0 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 10.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 3.0 43.2 0.0 0.1 0.0 0.1 0.2 WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.3;skin 1: 27.7" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.5;Early spermatids: 27.7;Late spermatids: 63.8;Suprabasal keratinocytes: 17.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;U-698: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" 0.8 0.4 1.3 0.4 1.1 0.1 1.0 0.7 1.0 1.0 0.2 0.6 3.4 0.5 0.0 1.3 0.5 0.1 0.9 0.8 1.2 1.7 12.3 0.9 0.2 1.4 1.8 0.5 0.8 2.5 1.7 0.2 1.2 1.3 0.2 0.2 1.2 0.0 0.2 27.7 2.7 0.2 0.7 0.7 0.4 4.4 4.4 0.1 1.3 0.0 0.1 0.4 1.1 0.7 3.9 1.7 8.5 0.0 0.1 0.1 0.7 0.8 0.9 3.0 0.0 2.7 1.7 1.6 2.3 2.1 6.1 1.3 0.4 0.0 3.9 0.0 0.4 0.0 3.0 2.3 0.0 0.1 0.1 0.2 1.8 1.1 2.3 3.5 1.1 2.5 1.5 0.0 1.0 1.7 0.0 1.4 0.0 1.0 2.4 2.9 1.9 0.2 0.6 0.0 0.1 0.7 1.6 0.0 1.2 2.1 0.0 4.0 0.2 3.2 2.1 0.4 1.5 0.6 0.2 14.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 1.1 0.7 1.0 0.8 1.2 1.4 1.8 1.2 0.7 4.4 0.7 0.2 0.0 1.5 3.9 0.5 44.5 0.6 0.6 3.4 1.1 3.0 1.7 1.3 1.5 0.4 0.0 0.0 2.2 0.1 0.7 1.9 0.7 27.7 0.1 0.7 0.5 0.0 0.0 5.4 2.5 0.1 1.1 0.0 0.2 0.0 0.7 0.4 4.0 0.2 8.4 4.3 0.6 0.0 0.0 1.5 63.8 0.3 0.1 1.8 1.0 0.6 0.2 0.0 4.0 1.1 2.9 1.4 0.4 0.0 1.2 3.7 0.5 0.3 0.8 0.0 1.4 1.1 0.9 2.9 0.8 17.6 0.3 0.0 0.3 0.9 0.3 YWHAG "14-3-3γ, 14-3-3GAMMA, PPP1R170" ENSG00000170027 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma" P61981 7 76326799-76358991 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 337.4;skeletal muscle: 349.8" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 408.8;Suprabasal keratinocytes: 425.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013274, CAB018389, HPA026918" Approved Approved Approved Cytosol NA NA 66000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB013274: , CAB018389: AB_2217962, HPA026918: AB_10610566" "unprognostic (3.71e-2)" "prognostic unfavorable (4.53e-4)" "unprognostic (3.88e-2)" "unprognostic (1.25e-2)" "unprognostic (6.28e-3)" "unprognostic (2.40e-3)" "unprognostic (8.98e-3)" "prognostic unfavorable (5.34e-4)" "unprognostic (1.63e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.03e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (9.31e-2)" "unprognostic (1.51e-1)" "unprognostic (2.45e-2)" "unprognostic (1.70e-1)" 188.1 99.2 165.6 60.6 185.3 27.3 61.0 80.2 337.4 41.1 8.5 48.4 47.8 50.9 20.8 64.5 37.9 54.5 111.4 206.5 206.1 50.8 72.4 47.1 43.2 204.5 120.7 40.7 59.7 50.1 32.6 55.4 192.9 46.1 44.0 87.2 39.9 40.0 349.8 43.7 41.6 66.4 81.5 44.2 38.2 28.9 135.1 40.2 29.7 238.4 48.6 78.8 46.3 199.1 189.0 231.9 200.5 256.7 200.5 114.9 90.5 213.3 105.0 129.6 139.5 147.0 196.7 263.5 71.7 190.8 215.2 171.6 254.3 235.8 180.5 179.9 110.9 250.2 150.0 164.5 182.6 309.0 234.0 127.1 221.0 151.5 310.8 137.3 208.9 140.2 349.9 289.0 195.8 177.6 222.3 227.1 223.0 150.7 160.4 256.3 203.0 291.7 204.5 126.3 107.0 297.1 236.7 299.2 156.0 256.9 208.5 184.2 222.6 250.7 145.7 225.4 290.1 95.1 191.6 399.5 225.5 285.3 273.8 1.5 2.3 0.5 0.8 2.0 1.4 1.3 1.0 1.1 2.4 0.7 0.7 0.9 0.5 0.5 1.8 2.6 0.9 0.9 165.6 185.3 80.2 337.4 206.5 206.1 204.5 120.7 192.9 81.5 135.1 199.1 73.7 32.1 26.4 23.2 51.8 408.8 128.3 87.9 126.9 102.9 107.0 70.1 234.0 40.0 55.1 38.6 12.5 36.5 39.3 49.9 37.2 52.4 91.2 96.0 82.9 92.0 85.4 72.8 99.9 38.2 84.1 97.4 61.2 127.9 67.3 38.7 50.0 93.1 83.5 124.5 78.5 35.7 44.7 90.3 229.0 25.2 46.3 87.8 94.3 40.3 64.2 27.1 20.6 23.1 57.1 71.1 29.9 43.2 56.6 129.8 34.1 61.3 47.2 35.3 32.9 92.5 91.5 13.4 19.0 160.1 425.4 67.2 41.5 46.4 45.1 177.1 ZXDB ZNF905 ENSG00000198455 "Zinc finger X-linked duplicated B" P98169 X 57592011-57597477 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 31.7;Suprabasal keratinocytes: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 34.8" HPA043789 Approved Approved Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA043789: AB_2678673" "unprognostic (1.87e-1)" "unprognostic (3.22e-1)" "unprognostic (1.88e-1)" "unprognostic (8.61e-3)" "unprognostic (4.29e-2)" "unprognostic (2.80e-1)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (4.36e-1)" "unprognostic (9.04e-2)" "unprognostic (6.73e-2)" "unprognostic (2.16e-2)" "unprognostic (1.17e-3)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (4.02e-3)" "unprognostic (2.87e-3)" 3.6 3.1 3.7 3.4 3.6 8.2 4.8 4.6 4.0 4.5 2.8 3.6 2.8 5.2 3.1 3.3 5.5 4.2 3.6 3.5 4.2 3.6 14.5 3.4 4.8 3.9 3.9 5.8 6.0 6.1 2.3 2.6 4.1 4.9 3.7 3.3 3.3 4.3 4.2 4.7 3.4 5.7 3.8 4.1 4.1 1.5 3.6 3.3 5.3 4.8 4.5 4.3 2.7 4.2 5.5 6.4 4.1 5.5 6.8 6.7 5.6 3.9 4.8 3.1 3.2 2.7 4.0 4.8 5.6 7.0 4.9 6.1 11.9 20.5 6.0 11.7 6.4 2.6 8.3 7.3 8.8 4.5 2.9 5.9 34.8 8.0 21.4 6.8 9.4 5.2 3.0 5.0 8.4 3.9 4.0 3.7 16.5 2.2 8.0 5.0 14.9 2.7 4.2 8.7 3.5 6.5 7.7 5.6 6.1 9.2 5.8 4.9 8.3 6.7 12.9 5.8 3.9 0.0 2.1 6.4 4.8 3.9 3.1 0.0 0.0 0.0 0.3 0.1 0.2 0.2 0.2 0.5 0.1 0.2 0.4 0.2 0.0 0.1 0.1 0.2 0.2 0.1 3.7 3.6 4.6 4.0 3.5 4.2 3.9 3.9 4.1 3.8 3.6 4.2 4.6 6.4 2.6 1.0 6.4 31.7 11.4 3.7 12.5 3.5 10.6 4.8 6.1 8.6 3.5 1.8 0.0 2.4 7.3 2.8 3.9 2.9 0.0 9.8 6.1 5.6 0.0 4.0 2.8 3.7 1.6 6.0 7.1 14.5 0.0 4.4 3.9 12.0 1.1 6.7 3.7 7.8 0.0 2.2 8.1 0.2 5.0 2.7 7.2 1.9 1.4 1.0 2.1 4.0 3.6 4.0 1.7 5.7 7.3 17.1 2.2 2.9 3.5 3.5 0.0 7.1 4.6 0.2 0.2 9.7 38.1 2.9 4.8 1.8 4.6 16.1