Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADACL3 ENSG00000188984 "Arylacetamide deacetylase like 3" Q5VUY0 1 12716110-12728760 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "placenta: 1.6;skin 1: 1.2" "Cell type enhanced" "Detected in single" "Extravillous trophoblasts: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.01e-1)" "unprognostic (2.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 67.1" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Extravillous trophoblasts: 71.3;Hepatocytes: 29.3;Spermatogonia: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA037502: AB_10671759" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "prognostic favorable (5.59e-4)" "unprognostic (4.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (7.41e-2)" "unprognostic (1.03e-2)" "unprognostic (2.97e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-2)" "unprognostic (3.55e-1)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-3)" "unprognostic (1.17e-2)" 3.3 2.8 6.2 1.9 6.8 0.3 4.7 3.8 9.8 9.8 11.3 6.2 1.6 10.5 5.9 2.6 6.3 3.9 2.7 6.5 6.7 6.8 67.1 4.9 0.7 5.8 5.6 4.7 5.6 6.0 6.1 1.9 6.5 14.4 5.0 11.8 1.7 5.3 4.0 1.4 2.3 7.3 4.8 1.7 3.6 8.2 6.1 1.5 7.5 2.4 0.8 6.4 5.7 8.7 3.5 8.5 25.0 0.0 4.9 18.9 9.0 8.7 4.2 4.9 5.0 8.4 1.0 0.1 1.4 9.8 6.5 2.9 11.3 4.1 3.4 0.0 9.7 0.0 10.0 14.0 3.9 0.1 3.8 7.7 2.5 4.0 5.1 13.5 4.7 11.4 1.5 0.1 19.0 8.9 4.3 0.1 19.0 9.6 7.6 0.0 7.8 0.0 4.4 15.3 20.1 23.5 7.0 1.7 8.5 8.0 0.1 1.7 3.2 12.5 13.4 14.3 13.9 0.1 0.0 0.1 12.5 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 6.8 3.8 9.8 6.5 6.7 5.8 5.6 6.5 4.8 6.1 8.7 0.9 0.0 5.9 22.2 0.3 0.9 2.8 0.9 6.2 6.0 3.9 1.0 1.2 1.5 2.1 0.0 2.1 2.8 0.0 0.7 0.0 1.6 0.5 3.7 7.4 0.7 6.7 0.0 15.4 2.2 71.3 3.2 3.1 6.0 0.0 6.2 0.7 29.3 1.6 0.0 13.6 2.8 0.0 0.3 0.9 1.4 1.2 0.4 1.8 5.6 0.0 2.7 0.0 17.6 14.0 1.1 1.6 2.2 0.0 4.0 0.2 8.4 8.5 9.1 6.6 3.9 4.2 14.5 27.1 3.0 0.4 5.6 0.3 3.3 3.1 1.8 ABCA7 ABCX ENSG00000064687 "ATP binding cassette subfamily A member 7" Q8IZY2 19 1039997-1065572 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Phagocytosis, Transport" Translocase "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;pituitary gland: 28.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Bipolar cells: 70.6;Cone photoreceptor cells: 175.2;Extravillous trophoblasts: 303.3;Rod photoreceptor cells: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 20.4;HMC-1: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA041564 Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Plasma membrane" "Cell Junctions" "HPA041564: AB_2677550" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (7.26e-4)" "prognostic favorable (1.12e-4)" "unprognostic (8.88e-2)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (4.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "unprognostic (1.51e-3)" "unprognostic (3.68e-2)" "unprognostic (8.99e-3)" "unprognostic (2.08e-2)" "unprognostic (3.66e-1)" "unprognostic (7.88e-2)" "unprognostic (7.85e-2)" 4.4 3.0 3.4 5.5 3.9 27.4 3.3 4.0 6.1 3.2 11.5 3.8 2.3 1.2 0.2 7.6 2.1 2.1 3.1 3.6 3.7 6.4 4.2 9.5 8.5 5.8 4.5 0.5 7.7 2.7 28.7 1.2 5.3 5.3 1.2 25.5 8.6 1.1 3.8 5.9 10.1 0.5 3.0 26.6 3.8 1.7 4.1 10.0 5.7 0.3 3.2 2.3 2.8 3.2 4.7 6.4 0.5 4.4 7.2 2.2 7.3 0.8 1.0 0.4 0.6 5.2 2.8 13.9 5.6 1.3 0.6 8.0 1.3 6.2 0.4 10.2 2.5 6.7 20.4 5.6 1.8 3.9 40.3 3.8 1.8 0.9 1.2 4.4 1.4 7.7 10.2 6.9 1.3 2.2 4.3 2.2 0.9 3.3 2.5 3.1 0.8 11.6 3.8 6.0 0.3 1.3 8.2 1.9 1.2 1.1 4.6 7.1 2.2 0.4 1.6 3.7 0.8 9.9 6.6 5.7 2.1 7.4 2.0 2.8 1.4 5.9 1.8 1.2 1.1 0.6 0.9 1.2 2.1 0.9 0.8 1.5 3.3 1.1 1.3 7.3 0.4 1.3 3.4 3.9 4.0 6.1 3.6 3.7 5.8 4.5 5.3 3.0 4.1 3.2 4.1 73.7 21.9 8.5 13.2 3.3 0.8 10.7 5.2 70.6 4.8 2.2 6.0 4.3 14.0 5.5 175.2 4.6 9.1 14.7 1.9 2.7 7.3 8.9 1.4 2.9 3.5 13.3 12.9 2.5 303.3 1.5 5.6 6.9 10.1 2.0 2.5 4.9 7.9 15.2 11.5 4.7 16.2 12.6 7.5 4.8 0.0 12.7 0.0 4.7 19.6 13.1 9.2 1.5 2.4 7.0 9.6 0.0 12.0 1.5 1.7 1.3 17.5 149.1 0.0 2.7 2.7 0.7 2.0 6.6 3.4 25.7 12.6 1.0 5.3 1.9 AC004556.3 ENSG00000276345 "39S ribosomal protein L23, mitochondrial" Unmapped 2585-11802 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 24.0" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 35.6;Hofbauer cells: 23.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CACO-2: 94.7;K-562: 75.5;MOLT-4: 85.4;NB-4: 160.6;PC-3: 141.1;WM-115: 113.7" HPA050406 Uncertain Supported "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "Nucleoli fibrillar center" "HPA050406: AB_2681116" 3.8 0.0 2.5 4.0 3.0 0.0 19.4 2.8 3.2 0.0 2.6 10.3 0.1 5.0 14.3 0.0 4.9 5.9 24.0 2.4 2.7 6.7 8.5 1.6 0.0 3.1 3.7 6.3 6.8 0.0 2.1 3.4 5.0 0.0 1.2 7.5 0.3 14.5 5.1 9.9 0.5 2.4 4.1 5.0 2.4 2.8 9.9 2.6 0.0 0.1 4.5 2.8 0.2 0.0 0.1 0.1 0.0 0.0 42.0 27.8 43.4 46.5 33.2 94.7 0.8 0.1 0.1 0.0 0.0 0.6 0.7 0.3 18.0 0.2 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 51.1 0.0 31.4 48.3 75.5 42.5 0.4 0.4 85.4 160.6 0.0 0.2 141.1 0.5 22.8 0.2 44.0 27.1 0.2 0.6 0.0 0.2 0.1 0.0 70.4 0.0 0.0 0.0 0.1 0.3 0.4 0.5 0.3 0.1 0.8 0.3 113.7 12.3 3.4 2.2 1.7 6.2 1.4 1.7 2.5 3.5 3.0 2.0 2.6 2.9 1.0 2.1 2.8 2.8 4.0 2.1 2.5 3.0 2.8 3.2 2.4 2.7 3.1 3.7 3.4 2.4 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 35.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 AC091959.1 ENSG00000275740 "Novel readthrough transcript" 5 146203550-146339251 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA035944, HPA036422" Approved Approved "Nuclear speckles" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear speckles" "HPA035944: AB_10670672, HPA036422: AB_10669987" "unprognostic (6.42e-2)" "unprognostic (7.72e-4)" "unprognostic (2.05e-2)" "unprognostic (4.95e-2)" "unprognostic (1.51e-2)" "unprognostic (1.13e-2)" "unprognostic (3.24e-2)" "unprognostic (8.78e-2)" "unprognostic (1.42e-1)" "unprognostic (3.61e-2)" "unprognostic (1.17e-1)" "unprognostic (3.77e-3)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (1.56e-2)" "unprognostic (2.12e-2)" 0.5 0.5 0.2 1.4 0.6 2.4 0.5 1.9 0.8 1.0 0.8 0.6 1.5 0.5 0.0 1.2 1.0 0.4 0.6 0.4 1.0 0.5 0.4 0.7 1.3 0.4 0.3 1.3 0.7 0.9 0.0 0.9 0.3 0.5 0.7 0.7 0.9 0.6 0.6 0.3 1.1 1.0 0.0 0.7 0.9 6.7 0.6 1.8 1.5 0.7 1.2 0.8 0.1 0.8 7.2 11.4 5.6 5.5 1.7 1.7 5.0 8.9 5.4 10.4 10.7 12.4 5.9 8.6 5.3 4.8 6.6 5.5 8.2 7.9 8.9 16.0 4.5 10.0 5.5 1.3 1.2 12.0 9.5 2.4 1.0 9.9 6.1 1.7 3.3 3.2 13.1 5.4 3.3 3.7 9.6 0.0 5.1 3.2 7.4 9.6 10.8 4.8 0.7 9.2 5.6 3.9 12.9 2.9 4.0 1.9 9.3 1.7 6.8 5.8 6.7 6.9 8.9 6.4 14.9 13.4 6.3 6.9 6.6 18.2 7.0 14.5 10.4 7.2 11.6 10.3 9.5 8.2 7.5 12.2 10.0 9.9 10.3 10.4 12.0 10.2 9.3 7.8 0.2 0.6 1.9 0.8 0.4 1.0 0.4 0.3 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.4;placenta: 16.0" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 33.0;Extravillous trophoblasts: 106.2;Syncytiotrophoblasts: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.9;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 3.9;NK-cells: 1.1" "Cell line enhanced" "Detected in some" "BEWO: 51.2;HEL: 17.1;SK-BR-3: 28.0;U-937: 10.7" "Group enriched" "Detected in many" 5 "amygdala: 2.2;basal ganglia: 7.9;cerebral cortex: 4.9;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" Nucleoplasm "HPA013819: AB_1846126, HPA073493: AB_2686610" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.90e-2)" "unprognostic (8.15e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "unprognostic (6.20e-2)" "unprognostic (8.47e-2)" "unprognostic (8.45e-2)" "unprognostic (1.13e-4)" "unprognostic (5.13e-3)" "unprognostic (3.22e-1)" "unprognostic (5.58e-3)" "unprognostic (6.09e-2)" 6.7 1.0 1.5 1.0 1.0 0.7 2.8 1.5 1.3 1.7 0.9 1.9 0.9 0.9 2.8 1.6 2.3 1.3 1.3 1.0 0.5 1.5 9.4 1.6 1.1 1.4 1.4 0.4 0.9 0.4 0.5 16.0 1.3 0.6 2.1 0.7 2.2 0.4 0.6 2.6 1.1 1.1 0.6 0.7 1.1 0.8 1.1 0.4 2.9 0.9 2.1 1.8 2.3 1.3 0.1 0.0 0.2 0.4 2.4 0.2 51.2 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.1 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 17.1 0.4 3.1 0.1 0.2 1.9 0.5 0.5 0.0 0.1 0.0 0.1 0.5 2.2 0.4 0.3 0.3 0.0 0.2 0.1 0.7 0.2 0.1 0.0 0.1 0.7 7.5 0.3 0.1 1.3 28.0 0.1 2.9 2.8 0.3 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.1 0.1 10.7 0.1 0.4 0.1 3.9 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.1 0.4 1.1 0.3 0.1 0.0 0.1 1.5 1.0 1.5 1.3 1.0 0.5 1.4 1.4 1.3 0.6 1.1 1.3 1.0 0.0 0.0 9.8 0.1 0.1 0.1 0.3 0.0 0.7 1.2 0.3 0.8 1.5 3.3 0.0 2.1 33.0 0.3 3.0 1.9 0.1 3.0 3.7 0.8 3.3 1.8 0.0 2.0 0.0 106.2 2.1 0.0 5.9 2.5 2.5 4.6 7.0 5.3 1.7 1.2 0.6 0.0 0.6 0.4 1.8 0.3 0.4 0.0 5.6 0.1 2.6 0.0 1.0 4.5 0.8 0.5 1.2 0.1 0.4 1.6 0.5 3.4 1.0 0.0 0.4 0.3 4.8 5.4 0.0 0.0 73.6 0.5 0.5 1.1 0.6 ADA ADA1 ENSG00000196839 "Adenosine deaminase" P00813 20 44619522-44652233 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 507.2;lymphoid tissue: 259.0" "Cell type enhanced" "Detected in many" "dendritic cells: 76.4;Extravillous trophoblasts: 128.2;NK-cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 168.5;NK-cell: 94.5;non-classical monocyte: 362.8;plasmacytoid DC: 218.6" "Group enriched" "Detected in all" 4 "dendritic cells: 218.6;monocytes: 362.8;NK-cells: 94.5" "Group enriched" "Detected in many" 5 "JURKAT: 570.9;MOLT-4: 1915.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (6.77e-5)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" 16.6 6.3 6.9 18.5 8.2 20.2 10.9 6.8 9.4 7.3 5.6 5.7 507.2 3.8 1.7 9.0 5.6 9.2 17.8 6.9 7.0 3.3 4.4 6.2 33.4 7.2 8.2 2.1 5.3 1.5 1.3 4.6 7.2 4.3 3.6 0.3 4.7 2.8 5.3 6.0 17.9 5.7 6.1 17.5 46.0 2.4 8.7 259.0 5.8 6.4 26.4 9.3 5.4 8.8 14.0 37.7 19.2 13.2 35.6 48.7 30.5 13.7 7.8 13.2 9.3 17.5 14.8 38.4 15.8 17.9 24.7 2.2 13.2 55.1 7.3 2.9 17.2 7.8 6.6 13.5 15.0 6.3 20.3 234.3 23.2 5.1 9.0 12.6 50.3 570.9 20.4 30.7 6.0 33.1 1915.5 28.9 5.2 17.2 13.5 102.3 25.8 95.0 2.3 0.0 0.7 9.3 20.2 4.4 24.2 24.0 4.5 19.1 16.9 10.1 18.6 20.5 2.8 40.1 27.3 82.3 3.5 32.5 9.0 0.5 9.8 1.2 43.3 168.5 27.8 7.5 35.5 51.0 35.2 7.6 27.3 38.6 2.5 94.5 362.8 218.6 29.8 57.4 6.9 8.2 6.8 9.4 6.9 7.0 7.2 8.2 7.2 6.1 8.7 8.8 18.2 0.0 1.9 2.9 13.5 12.9 3.4 10.0 13.6 0.0 2.7 3.2 2.1 0.0 4.8 1.8 0.0 2.9 76.4 0.8 0.0 3.7 0.4 0.7 9.1 17.0 0.0 10.7 0.2 19.7 128.2 19.7 14.8 0.8 0.0 3.5 7.1 3.6 28.5 0.0 0.2 1.5 10.2 20.8 25.5 1.8 42.3 27.6 8.8 3.7 37.4 3.8 56.7 0.5 9.4 10.7 0.3 2.6 31.4 6.0 0.7 3.0 2.4 0.0 13.1 1.9 14.1 0.3 6.2 12.9 13.9 3.7 30.9 6.8 4.9 2.7 ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388455 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 166.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2;Extravillous trophoblasts: 400.8;Oligodendrocyte precursor cells: 99.0;Syncytiotrophoblasts: 129.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "MAIT T-cell: 6.1" "Lineage enriched" "Detected in single" 62 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 154.2;hTEC/SVTERT24-B: 94.3;U-2197: 93.2;U-251 MG: 86.2;U-87 MG: 70.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" 11.4 0.1 2.0 6.0 4.0 0.1 4.6 1.6 2.1 18.2 3.5 0.4 0.2 6.3 0.0 0.4 0.2 11.8 0.7 1.0 2.5 1.0 0.2 1.3 3.2 6.0 2.7 8.8 0.5 0.1 1.1 166.5 3.1 0.3 0.6 0.3 1.1 0.0 0.1 0.4 0.5 4.3 1.8 1.6 0.5 0.9 10.4 1.8 0.3 0.0 3.5 11.6 0.5 3.0 16.8 2.5 6.5 0.1 18.7 38.3 0.0 42.7 3.5 14.2 35.5 0.0 0.0 0.0 0.0 154.2 30.0 0.0 0.2 1.4 15.5 1.9 0.6 0.2 25.1 0.0 2.9 0.0 33.2 47.0 0.0 94.3 2.9 27.1 0.0 0.0 0.0 0.2 11.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 4.8 4.4 0.4 44.1 0.5 28.4 5.0 0.0 0.7 2.5 0.1 0.1 0.0 50.9 16.9 93.2 86.2 0.0 0.5 0.0 70.7 0.1 32.3 0.0 0.0 0.0 0.3 0.0 6.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 2.0 4.0 1.6 2.1 1.0 2.5 6.0 2.7 3.1 1.8 10.4 3.0 0.5 0.0 1.9 22.5 0.3 1.5 0.4 3.0 0.0 2.1 1.7 3.6 2.3 0.0 0.5 0.0 102.2 14.0 0.5 0.7 0.0 8.0 10.9 10.7 16.6 1.6 0.0 0.0 7.4 1.1 400.8 34.5 0.5 1.8 49.5 7.8 2.5 0.2 15.5 6.7 19.0 1.0 4.1 0.6 3.1 1.7 16.8 0.8 1.8 14.0 9.0 3.3 1.0 99.0 52.2 2.2 0.1 0.7 0.3 1.0 0.7 0.4 6.5 30.5 0.0 5.1 13.4 6.0 5.0 0.0 0.6 129.2 4.7 28.1 0.9 0.5 ADM AM ENSG00000148926 Adrenomedullin P35318 11 10305073-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 340.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 590.8;Extravillous trophoblasts: 1217.1;Syncytiotrophoblasts: 1084.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "neutrophil: 242.2" "Lineage enriched" "Detected in many" 18 "granulocytes: 242.2" "Cell line enhanced" "Detected in many" "ASC diff: 684.6;fHDF/TERT166: 357.4;HSkMC: 410.9;U-138 MG: 390.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016075, HPA068955" Approved "Secreted to blood" NA NA 31000 340000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016075: AB_628693, HPA068955: " "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (1.55e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (8.13e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.33e-4)" "unprognostic (9.70e-3)" "unprognostic (2.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.62e-2)" 340.2 29.9 12.9 32.2 18.3 43.9 195.9 28.1 15.2 162.1 17.9 60.6 8.0 20.3 3.1 84.6 71.0 30.0 153.3 10.6 15.5 123.8 90.5 157.6 17.1 19.7 18.0 33.1 24.6 23.5 43.3 102.8 16.5 26.8 11.4 16.7 52.7 1.6 79.3 169.8 49.5 7.6 16.8 34.5 55.5 4.9 21.6 4.1 52.7 14.3 3.5 85.1 224.3 18.6 35.4 29.2 33.8 9.8 684.6 306.7 51.8 263.6 263.9 260.5 175.7 142.4 43.9 0.1 11.7 357.4 136.9 51.0 9.5 40.6 191.9 0.7 13.9 1.1 16.1 18.0 88.0 1.6 1.1 410.9 34.7 30.8 44.6 89.9 60.4 0.5 0.4 0.7 64.3 1.2 0.2 10.6 65.7 8.4 13.6 1.0 1.1 54.5 16.7 48.6 1.1 3.2 101.0 23.7 0.6 36.4 31.4 0.3 17.9 390.0 5.5 233.2 37.9 2.7 29.5 10.5 112.0 0.2 117.0 0.0 7.0 0.0 0.0 7.7 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.1 242.2 0.0 13.6 0.0 0.3 1.9 12.9 18.3 28.1 15.2 10.6 15.5 19.7 18.0 16.5 16.8 21.6 18.6 347.7 9.6 12.3 17.0 14.2 192.1 590.8 194.4 182.1 2.7 28.0 46.9 104.6 18.6 136.2 3.7 8.4 134.6 9.1 266.7 15.6 135.7 0.5 80.8 58.1 99.1 67.5 4.0 0.4 30.5 1217.1 202.8 55.0 210.9 9.5 30.1 95.7 18.6 71.4 3.3 3.0 127.6 181.0 69.6 57.7 2.6 132.7 107.9 40.9 6.5 8.1 4.9 1.0 1.5 0.1 61.7 298.3 19.2 20.0 218.9 14.0 60.1 38.7 15.3 0.0 73.3 76.5 5.1 4.9 182.3 125.6 1084.8 14.7 8.1 55.5 224.5 AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442356-134459284 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "adrenal gland: 3039.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 649.2;Cytotrophoblasts: 1105.1;Extravillous trophoblasts: 1284.9;Ionocytes: 697.8;Syncytiotrophoblasts: 2022.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 1667.3;BJ hTERT+: 3096.2;RPTEC TERT1: 1447.8;U-87 MG: 1343.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol No No 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: AB_10601563, HPA052751: AB_2681935" "unprognostic (2.76e-2)" "unprognostic (2.84e-2)" "unprognostic (2.02e-2)" "unprognostic (1.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.26e-1)" "unprognostic (4.18e-2)" "unprognostic (5.09e-2)" "unprognostic (2.51e-3)" "unprognostic (2.47e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.44e-5)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.00e-4)" 65.1 3039.1 83.1 38.4 89.3 21.9 52.3 91.8 97.4 41.4 80.9 40.1 20.5 42.4 44.0 28.2 38.7 40.2 208.2 84.1 92.5 218.0 19.3 55.0 74.6 101.6 96.9 60.5 34.4 111.2 76.5 203.7 104.9 34.4 30.9 36.5 41.9 332.7 330.0 26.6 50.8 39.6 91.4 62.8 51.4 44.9 88.7 54.9 44.3 396.9 62.5 67.3 35.0 101.4 184.2 1667.3 186.5 261.4 785.9 212.3 494.6 177.2 3096.2 259.3 335.0 75.8 170.6 0.0 79.2 301.5 1143.3 78.6 204.0 175.3 206.6 65.2 168.2 93.4 225.0 230.1 1117.9 0.1 0.8 196.9 133.4 367.6 98.3 252.8 370.3 181.1 0.1 62.4 292.4 3.5 283.3 131.0 309.2 13.9 1.8 292.9 116.5 138.8 1447.8 915.5 137.1 301.6 1261.5 1.5 134.3 121.3 0.6 140.6 289.6 254.5 116.0 22.7 195.6 168.2 196.9 470.0 1343.5 0.7 153.0 125.7 106.4 5.6 147.6 72.3 135.2 133.0 124.7 144.5 145.3 121.7 162.9 156.7 8.5 119.7 39.2 20.4 94.9 230.2 83.1 89.3 91.8 97.4 84.1 92.5 101.6 96.9 104.9 91.4 88.7 101.4 34.1 12.8 19.4 9.1 50.3 20.6 55.3 66.1 20.5 36.2 11.7 27.9 202.4 25.8 26.4 649.2 8.4 1105.1 35.1 2.3 164.4 112.7 5.0 6.1 20.9 50.9 31.0 20.2 10.5 41.5 1284.9 100.3 20.4 5.9 53.8 59.8 82.1 2.6 394.1 72.3 18.7 15.1 697.8 172.8 53.9 14.5 79.2 127.7 30.2 14.0 76.3 49.3 66.9 5.5 12.4 51.0 4.5 77.5 72.6 25.6 0.3 60.2 24.9 24.1 59.2 98.9 54.5 22.6 100.2 10.5 11.6 2022.4 49.9 70.5 6.7 54.2 ANGPT4 ENSG00000101280 "Angiopoietin 4" Q9Y264 20 869900-916334 "Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 7.2;breast: 6.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 52.9;Late spermatids: 17.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "ASC diff: 33.7;BEWO: 48.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013260, CAB013305" Uncertain "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB013260: , CAB013305: " "unprognostic (1.77e-1)" "unprognostic (3.25e-1)" "unprognostic (4.30e-2)" "unprognostic (1.04e-3)" "unprognostic (6.37e-2)" "unprognostic (3.41e-1)" "unprognostic (5.82e-4)" "unprognostic (1.25e-1)" "unprognostic (7.10e-2)" "unprognostic (3.66e-4)" "unprognostic (9.01e-2)" "unprognostic (1.71e-1)" "unprognostic (5.25e-2)" "unprognostic (1.23e-2)" "unprognostic (1.55e-1)" "unprognostic (2.95e-4)" "unprognostic (9.14e-2)" 7.2 0.3 0.3 0.1 0.3 0.0 6.6 0.2 0.3 3.8 0.1 0.3 0.1 3.3 2.1 0.2 3.3 0.3 0.2 0.2 0.4 0.2 0.2 1.2 0.1 0.3 0.3 3.9 0.1 0.1 0.0 0.0 0.4 0.5 0.1 0.1 0.3 0.4 0.0 1.4 0.3 1.1 0.2 0.0 0.3 0.6 0.4 0.2 1.7 0.6 0.0 1.0 2.2 0.3 0.2 0.0 0.0 0.0 33.7 0.0 48.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.3 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.3 0.3 0.0 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 52.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.3 17.0 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.9 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 ARID3A "BRIGHT, DRIL1" ENSG00000116017 "AT-rich interaction domain 3A" Q99856 19 925781-975939 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 23.4;testis: 17.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 191.8;Extravillous trophoblasts: 492.4;Langerhans cells: 163.7;Syncytiotrophoblasts: 518.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 206.5;CACO-2: 72.3;Hep G2: 65.8;K-562: 95.6;THP-1: 66.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004793, HPA076330" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA004793: AB_1847870, HPA076330: AB_2732309" "unprognostic (1.34e-1)" "unprognostic (2.62e-3)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (1.31e-3)" "unprognostic (5.67e-2)" "unprognostic (3.40e-3)" "unprognostic (1.38e-1)" "unprognostic (5.22e-2)" "unprognostic (2.54e-1)" "prognostic favorable (1.95e-5)" "unprognostic (4.00e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (3.29e-1)" "unprognostic (2.67e-3)" "unprognostic (1.30e-1)" "unprognostic (8.95e-2)" 3.4 1.8 2.3 4.9 1.6 10.3 2.2 3.4 3.8 2.5 2.7 2.4 3.2 2.2 0.7 3.0 2.3 0.8 1.9 1.9 1.2 3.9 2.1 4.4 3.5 2.0 1.6 1.2 3.1 2.1 3.3 23.4 2.1 1.9 1.2 0.8 2.0 0.7 1.7 3.1 3.6 1.3 1.7 6.6 2.6 17.0 2.2 2.5 1.6 1.1 2.7 2.2 3.0 1.8 3.8 5.0 17.2 4.3 7.2 5.4 206.5 16.5 10.7 8.8 5.8 72.3 0.6 1.6 3.8 5.6 2.2 1.5 7.0 3.9 3.8 22.5 5.0 7.2 6.5 65.8 3.1 25.1 17.8 7.7 5.5 5.5 1.4 1.4 2.9 5.7 95.6 20.3 2.6 5.8 9.8 28.5 16.6 2.6 1.0 21.9 5.4 13.9 1.1 3.7 8.3 15.8 5.3 4.3 3.1 37.7 7.6 66.7 4.9 5.8 7.8 8.4 1.9 47.0 45.3 12.5 3.8 14.5 4.0 0.7 1.6 1.1 0.3 1.4 0.3 0.9 0.2 0.3 1.0 0.6 0.3 0.1 4.1 1.3 2.1 6.4 0.2 0.7 2.3 1.6 3.4 3.8 1.9 1.2 2.0 1.6 2.1 1.7 2.2 1.8 4.7 6.4 2.8 2.9 30.2 14.8 8.0 8.9 9.6 8.4 7.4 7.5 8.0 0.0 2.4 14.7 8.4 191.8 56.0 4.0 9.8 5.7 41.3 14.8 19.0 14.1 46.9 9.9 8.5 3.3 492.4 18.9 5.1 15.2 3.8 11.4 11.4 7.6 98.2 6.7 8.0 11.3 4.1 41.0 163.7 4.7 7.2 41.0 16.0 24.4 60.4 2.2 13.4 6.6 2.7 14.3 0.3 6.4 50.9 6.9 10.8 5.7 1.1 4.4 0.0 3.2 10.5 2.9 9.9 8.1 15.3 518.3 10.7 8.2 5.5 2.1 ARSK "DKFZp313G1735, TSULF" ENSG00000164291 "Arylsulfatase family member K" Q6UWY0 5 95555101-95605102 "Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 19.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042384 Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA042384: AB_10795703" "unprognostic (9.50e-2)" "unprognostic (1.37e-1)" "unprognostic (2.03e-3)" "unprognostic (2.39e-1)" "unprognostic (3.33e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (2.59e-4)" "unprognostic (3.39e-1)" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (7.61e-2)" "unprognostic (2.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.91e-2)" "unprognostic (2.32e-1)" "unprognostic (8.20e-2)" "unprognostic (1.06e-2)" 3.0 3.7 2.1 2.2 2.3 2.3 3.3 2.8 3.0 3.8 2.1 2.7 2.2 3.6 4.2 2.9 3.2 3.1 2.6 2.4 2.1 5.4 3.7 2.9 2.7 1.9 1.9 5.8 4.9 19.1 2.6 5.5 2.3 4.9 2.5 3.6 2.8 4.9 2.3 3.3 2.2 3.0 1.7 2.4 4.2 1.6 2.6 3.7 5.0 2.7 2.0 3.2 3.3 2.2 5.1 3.2 6.6 6.6 32.4 16.8 9.5 15.9 9.2 6.1 12.4 3.9 7.8 6.9 8.1 5.5 10.9 4.6 5.8 10.1 13.3 7.4 8.5 5.5 7.7 6.7 9.4 3.1 4.4 12.4 8.9 9.2 5.9 12.8 10.0 9.3 5.6 7.4 13.7 2.5 8.5 5.9 8.6 1.6 15.3 5.2 10.6 11.0 14.1 1.2 4.7 4.8 9.7 3.1 10.0 9.1 8.9 3.2 18.1 9.6 7.8 15.0 9.9 6.2 11.2 8.4 9.6 8.0 36.5 12.9 1.1 2.1 4.0 1.2 4.7 4.9 4.7 5.4 0.6 5.0 7.0 5.2 0.9 3.3 0.7 2.2 3.9 1.8 2.1 2.3 2.8 3.0 2.4 2.1 1.9 1.9 2.3 1.7 2.6 2.2 6.8 3.2 2.2 9.1 6.6 4.5 6.8 7.4 5.7 7.3 4.4 7.2 4.6 1.5 3.7 7.3 12.5 11.8 6.6 1.9 3.9 4.1 9.2 7.1 10.3 6.2 3.0 10.1 11.0 2.5 47.4 13.6 2.0 5.7 22.9 8.1 6.8 16.5 4.6 10.1 9.7 2.0 10.2 3.2 5.4 2.9 10.8 4.9 5.4 7.5 5.1 12.7 14.4 7.1 10.0 2.6 3.2 11.7 7.1 3.9 3.2 4.8 6.8 10.4 0.0 10.2 10.9 7.4 8.6 5.1 7.0 5.1 9.8 11.8 3.4 2.1 ASCL2 "ASH2, bHLHa45, HASH2" ENSG00000183734 "Achaete-scute family bHLH transcription factor 2" Q99929 11 2268498-2270588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.9;salivary gland: 8.0;skin 1: 7.3" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 1042.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 76.1;stomach cancer: 23.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 7.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "BEWO: 25.1;NB-4: 8.1;OE19: 14.2;SCLC-21H: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (2.71e-3)" "prognostic favorable (5.11e-4)" "unprognostic (2.03e-1)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (2.69e-2)" "unprognostic (2.93e-2)" "unprognostic (7.88e-2)" "unprognostic (3.79e-2)" "unprognostic (1.22e-2)" "prognostic favorable (4.73e-4)" "unprognostic (5.85e-2)" "unprognostic (1.45e-6)" "unprognostic (8.86e-3)" "unprognostic (5.48e-2)" "unprognostic (6.12e-4)" "unprognostic (1.07e-3)" 0.3 0.2 1.0 1.2 0.6 0.8 0.7 0.5 0.9 2.4 0.4 3.9 6.9 2.2 0.5 1.6 0.4 0.1 0.1 0.9 0.5 1.7 0.8 0.6 0.7 1.7 2.0 0.1 0.7 0.1 0.1 5.5 1.0 2.3 2.5 0.0 8.0 1.6 0.2 7.3 5.5 0.1 1.1 2.3 2.1 0.8 1.4 0.5 0.5 0.0 0.6 1.5 1.9 2.3 0.0 0.0 0.4 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.7 0.0 8.1 0.6 14.2 0.0 0.0 0.0 0.0 0.0 0.6 20.5 0.1 0.0 0.5 0.0 0.0 2.5 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.9 1.2 7.9 2.2 1.7 0.1 0.0 0.5 1.3 0.8 0.0 0.1 1.3 0.9 0.0 1.4 0.0 0.0 0.4 1.0 0.6 0.5 0.9 0.9 0.5 1.7 2.0 1.0 1.1 1.4 2.3 1.2 0.0 0.0 0.0 1.4 13.6 14.1 3.3 23.3 0.0 7.2 3.3 0.9 1.5 0.7 20.2 0.0 18.7 29.2 14.4 7.9 0.2 0.1 1.4 4.7 2.6 78.2 4.4 0.0 0.0 1042.9 1.5 10.2 3.5 0.0 0.0 23.2 0.5 31.1 0.0 0.0 31.4 2.0 22.0 7.0 0.2 1.8 14.3 1.8 3.7 22.6 0.0 110.2 0.0 0.0 0.0 3.6 1.5 1.3 6.5 9.1 0.4 1.0 0.1 0.0 0.1 0.3 0.3 13.7 9.1 4.7 23.3 8.9 0.1 112.1 9.4 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 298.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 16.5 20.4 16.6 8.4 17.0 15.0 16.9 16.5 20.4 16.2 17.7 16.0 13.6 15.6 7.9 16.8 14.0 7.7 26.1 16.2 15.5 27.3 57.9 17.3 12.2 20.1 16.6 13.4 22.8 14.8 30.6 12.9 18.3 21.6 4.6 5.7 18.3 6.7 44.3 20.5 18.1 5.2 14.7 20.7 22.7 30.0 17.2 8.3 25.9 5.8 6.4 16.0 14.2 21.5 19.3 33.3 13.0 17.9 7.5 9.3 55.4 17.7 12.6 19.3 19.5 20.3 21.3 19.2 18.1 12.4 16.3 9.8 12.0 13.1 6.2 12.9 41.0 21.4 28.7 298.1 25.5 19.1 29.9 10.9 13.9 9.5 6.6 10.0 19.5 16.0 22.0 25.0 11.6 65.0 16.9 41.8 15.5 32.8 23.5 19.2 18.7 39.4 18.0 17.0 32.4 34.8 14.6 42.2 35.2 12.3 27.2 41.4 16.6 35.7 24.5 26.4 22.8 20.2 12.5 21.6 19.2 19.3 21.3 24.0 11.7 8.6 6.6 8.0 3.7 9.0 10.0 8.8 14.7 9.0 7.7 5.8 2.7 8.0 10.4 9.3 5.3 5.6 16.6 17.0 16.5 20.4 16.2 15.5 20.1 16.6 18.3 14.7 17.2 21.5 13.9 9.6 44.7 19.9 24.1 13.4 23.7 24.4 23.3 23.3 19.6 15.6 13.6 27.1 19.8 14.7 41.7 73.7 25.8 29.3 39.2 24.2 49.1 16.2 14.9 16.1 25.0 17.9 12.4 26.2 222.6 17.5 46.9 20.1 21.5 31.0 12.8 56.1 44.7 50.5 12.1 31.5 20.3 26.7 18.6 96.0 11.8 21.7 19.6 1.9 23.8 57.8 19.6 10.6 14.1 17.6 25.8 17.7 27.3 24.9 42.5 58.3 18.5 39.4 13.1 14.7 37.4 41.7 51.0 20.3 14.3 59.4 18.4 23.6 33.3 23.1 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 171.4;Extravillous trophoblasts: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 3900000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Plasma membrane" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 24.8 26.0 19.8 31.7 23.4 26.4 33.9 21.4 23.5 22.2 18.8 36.4 32.0 30.0 20.3 19.4 29.4 20.4 21.3 19.6 21.5 32.7 34.6 18.0 44.9 20.5 21.5 32.0 26.2 29.6 18.6 37.3 23.3 28.7 47.5 19.1 18.8 38.4 43.2 23.8 27.2 37.0 21.0 27.6 24.5 20.1 22.9 41.8 22.5 25.4 51.8 29.1 17.6 27.5 102.2 133.8 85.1 144.0 112.5 113.2 40.6 105.4 91.9 117.4 134.9 278.6 157.3 149.6 122.8 110.0 164.5 106.7 187.8 157.0 169.5 113.4 189.3 179.1 108.7 271.5 145.4 226.1 92.0 98.4 119.8 154.7 188.5 82.0 79.7 144.5 237.0 124.4 166.3 178.7 203.4 112.1 330.3 167.4 84.9 185.8 117.3 133.4 126.4 146.5 129.3 87.8 84.3 103.1 124.3 189.2 169.7 82.9 70.2 96.0 101.2 127.3 65.8 160.3 195.7 300.1 85.6 124.5 146.8 12.6 16.4 0.4 34.6 23.5 59.1 56.6 49.0 53.8 36.3 39.9 50.0 46.9 1.8 55.4 21.1 31.7 50.2 29.0 19.8 23.4 21.4 23.5 19.6 21.5 20.5 21.5 23.3 21.0 22.9 27.5 7.2 12.8 19.3 18.6 34.7 15.0 28.2 55.0 30.7 10.0 18.2 16.1 21.1 28.6 33.3 23.9 4.2 171.4 23.3 17.6 27.4 45.2 1.1 20.7 28.2 6.1 19.2 32.2 15.4 49.3 166.3 25.3 22.4 20.8 25.3 32.9 5.3 22.2 52.4 10.1 15.4 33.8 26.4 14.4 10.8 1.7 23.9 20.2 30.2 2.8 26.1 21.3 26.8 16.6 25.7 32.4 28.5 34.3 36.3 24.0 18.8 52.7 27.3 14.7 26.3 19.2 29.0 3.3 43.8 24.6 8.5 95.4 29.8 40.7 58.4 18.1 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Extravillous trophoblasts: 102.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favorable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 8.7 10.9 6.8 5.4 6.9 0.9 5.3 7.9 7.9 17.2 5.5 12.3 7.1 23.9 5.9 5.9 19.8 6.6 8.0 9.4 6.2 3.7 2.7 17.0 3.5 8.5 7.9 15.0 4.2 4.2 6.2 18.4 5.3 14.0 14.6 3.4 5.2 8.9 14.6 14.9 7.4 17.3 7.3 7.4 13.6 6.7 11.0 17.3 12.3 7.8 2.7 11.4 8.0 5.6 0.0 13.9 27.2 0.5 9.6 4.1 12.0 0.4 1.3 0.9 1.7 52.3 5.0 1.0 1.7 8.0 1.0 0.4 5.7 0.1 1.9 2.4 3.1 0.0 2.4 78.8 1.0 0.1 0.1 2.4 2.1 2.2 0.6 1.6 2.4 5.1 0.2 1.2 1.4 0.3 13.9 0.1 5.3 86.9 0.6 9.9 1.6 0.1 2.6 0.3 8.4 5.5 0.5 0.3 4.8 20.0 1.0 0.3 6.3 5.3 9.6 7.6 1.7 0.1 3.0 3.8 2.5 0.6 2.6 3.2 0.0 0.0 0.1 0.0 0.4 0.5 1.1 0.2 0.0 1.8 2.3 0.4 0.0 1.0 0.0 0.0 0.0 0.3 6.8 6.9 7.9 7.9 9.4 6.2 8.5 7.9 5.3 7.3 11.0 5.6 2.4 0.0 9.0 9.8 1.0 11.2 2.2 1.0 11.4 3.7 5.2 8.1 8.7 1.5 8.1 0.0 4.2 18.1 0.7 15.2 0.0 1.4 33.7 7.8 15.1 5.3 5.4 0.0 8.4 0.9 102.6 10.3 5.6 16.5 0.0 3.1 1.1 2.0 3.8 1.7 8.7 17.4 0.0 0.0 7.5 17.5 6.5 0.6 17.8 9.4 1.0 3.3 0.0 8.0 2.0 0.8 18.9 10.9 0.9 2.9 1.9 0.9 1.3 2.5 13.1 1.6 10.6 6.2 12.9 3.3 5.5 14.2 4.6 3.6 19.8 1.3 B4GALT7 "beta4Gal-T7, XGALT-1" ENSG00000027847 "Beta-1,4-galactosyltransferase 7" Q9UBV7 5 177600132-177610330 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042330 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA042330: AB_10796576" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (3.12e-1)" "unprognostic (5.97e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (9.53e-2)" "unprognostic (4.19e-3)" "unprognostic (3.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-3)" "unprognostic (2.00e-2)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (4.44e-2)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" 19.0 43.7 21.1 15.3 20.1 24.8 17.0 20.6 25.5 18.4 21.8 15.1 16.9 20.1 12.5 16.6 16.0 12.5 23.4 20.1 21.8 20.2 30.5 13.4 20.1 24.8 25.1 19.8 37.6 24.3 31.5 14.1 24.8 22.5 11.9 5.9 24.2 18.8 20.2 13.6 14.7 11.8 18.5 21.3 21.8 23.9 22.1 10.6 18.5 10.1 11.8 17.9 13.9 18.7 20.2 34.5 14.2 35.6 28.0 20.7 63.7 30.1 31.9 26.9 30.7 32.6 30.8 25.2 54.7 30.9 47.3 22.9 9.8 64.9 11.7 85.4 25.8 13.3 27.5 23.4 40.0 13.8 22.4 31.8 22.7 29.0 23.5 24.7 30.3 16.9 11.8 23.7 27.4 46.0 11.9 17.1 13.9 17.7 50.0 24.1 10.3 27.8 20.6 29.6 12.5 14.4 15.0 29.8 27.6 11.3 19.4 16.3 23.5 34.0 19.5 22.6 30.6 29.5 14.9 18.4 28.8 33.0 31.8 16.8 16.7 9.7 14.0 19.7 12.6 14.4 12.8 12.2 19.3 18.4 11.4 11.3 1.3 11.1 19.4 15.2 9.2 10.9 21.1 20.1 20.6 25.5 20.1 21.8 24.8 25.1 24.8 18.5 22.1 18.7 16.3 3.2 5.6 5.2 24.5 6.6 15.4 27.8 15.9 12.1 16.5 19.3 6.9 12.8 15.8 16.5 4.2 43.8 16.4 13.8 7.9 34.1 13.9 12.5 17.8 15.6 14.5 8.2 4.3 38.9 132.4 21.2 8.2 13.5 10.2 30.0 10.8 15.9 31.7 11.8 6.0 22.2 8.2 17.8 8.9 9.8 14.0 18.8 21.4 3.7 25.6 13.7 13.4 3.0 3.4 34.0 12.4 18.4 52.8 30.7 17.4 19.6 9.3 16.1 0.0 13.9 16.4 14.3 11.3 13.9 8.8 43.9 12.8 33.4 23.3 16.3 BEAN1 SCA31 ENSG00000166546 "Brain expressed associated with NEDD4 1" Q3B7T3 16 66427295-66493529 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.8;Early spermatids: 10.7;Excitatory neurons: 9.9;Extravillous trophoblasts: 10.9;Inhibitory neurons: 7.7;Late spermatids: 13.6;Oligodendrocyte precursor cells: 7.5;Spermatocytes: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AN3-CA: 9.2;BEWO: 4.2;RPTEC TERT1: 9.1;U-87 MG: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053851 Uncertain Uncertain Nucleoplasm,Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Centrosome "HPA053851: AB_2682280" "unprognostic (1.92e-1)" "unprognostic (5.79e-4)" "unprognostic (3.83e-2)" "unprognostic (3.38e-3)" "unprognostic (1.01e-1)" "unprognostic (4.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.13e-1)" "unprognostic (4.89e-1)" "unprognostic (1.59e-1)" "unprognostic (2.13e-3)" "unprognostic (4.18e-2)" "unprognostic (3.38e-2)" "unprognostic (1.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-2)" 0.7 0.3 1.3 0.3 1.2 0.8 0.6 2.4 4.1 0.8 0.0 0.6 0.2 0.8 0.3 0.6 1.1 0.4 0.9 2.4 0.7 0.5 0.7 0.6 0.2 5.1 1.6 0.9 0.5 0.6 0.3 1.5 5.0 0.4 0.2 1.7 0.5 0.1 1.0 0.9 0.4 0.2 0.7 0.4 0.4 1.1 3.0 0.0 0.7 0.1 0.2 0.6 0.6 1.7 0.5 0.8 0.8 9.2 0.1 0.1 4.2 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.4 0.1 0.4 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.4 0.6 0.0 0.0 0.3 1.6 0.4 0.1 1.3 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.2 0.2 0.1 0.4 0.0 0.1 0.3 9.1 0.3 0.0 0.1 0.1 0.1 1.4 0.5 0.1 0.0 0.1 0.2 2.0 0.0 0.3 0.3 0.0 0.0 4.8 0.1 1.0 0.2 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.1 0.0 0.9 0.0 0.0 1.3 1.2 2.4 4.1 2.4 0.7 5.1 1.6 5.0 0.7 3.0 1.7 0.1 0.0 0.0 2.0 0.0 0.1 0.3 0.2 0.0 0.6 0.2 0.6 1.4 0.0 0.2 0.0 0.0 5.8 0.0 0.1 0.0 0.4 10.7 0.2 0.2 0.4 0.0 0.0 9.9 0.0 10.9 0.4 0.0 0.2 0.0 0.3 0.7 0.0 1.0 0.0 7.7 0.0 0.0 0.8 0.4 13.6 0.3 0.1 3.6 3.7 0.0 0.0 1.0 7.5 2.6 1.7 0.0 2.2 0.0 1.7 0.0 0.1 0.1 1.4 0.0 0.2 0.3 6.6 0.3 0.0 0.1 2.9 0.1 0.5 0.0 0.8 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 C1QTNF6 "CTRP6, ZACRP6" ENSG00000133466 "C1q and TNF related 6" Q9BXI9 22 37180166-37199385 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.7;placenta: 29.6" "Cell type enriched" "Detected in many" 11 "Extravillous trophoblasts: 398.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 114.2;RT4: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002042 Enhanced Approved Nucleoplasm "Secreted to blood" No No 354000000 "Cluster 48: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA002042: AB_1078342" "unprognostic (9.65e-2)" "unprognostic (1.21e-2)" "unprognostic (2.32e-1)" "unprognostic (2.23e-3)" "unprognostic (1.25e-3)" "unprognostic (3.01e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.60e-6)" "unprognostic (6.96e-2)" "unprognostic (5.11e-2)" "unprognostic (2.61e-2)" "unprognostic (1.72e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.61e-2)" "unprognostic (5.36e-2)" "unprognostic (1.08e-3)" "unprognostic (1.52e-2)" 4.9 6.7 4.4 6.6 4.5 1.6 4.0 4.3 5.3 11.1 4.3 5.5 1.6 31.7 1.4 2.7 7.0 8.8 3.7 4.5 4.3 7.4 13.0 5.2 5.1 5.1 4.5 5.5 3.5 2.2 2.5 29.6 4.8 6.8 3.6 0.5 3.2 2.9 1.5 5.0 5.4 8.2 4.4 6.5 3.5 6.2 4.8 2.4 3.8 0.7 2.3 5.6 4.3 6.3 17.7 20.5 10.7 3.6 1.8 21.3 32.6 3.4 6.8 2.8 2.0 3.8 24.7 0.1 14.1 6.0 1.5 34.9 0.4 8.4 1.2 4.9 2.6 2.8 8.3 3.8 7.1 0.1 2.3 29.2 4.9 2.3 0.6 7.3 25.5 0.8 0.1 7.7 1.1 114.2 0.0 0.5 7.1 2.5 0.3 0.2 0.1 2.8 24.5 50.7 1.8 14.6 1.0 19.7 2.8 5.5 7.0 0.5 9.4 1.1 5.6 0.4 0.1 15.5 0.4 0.1 2.1 2.0 3.2 0.4 0.1 0.5 0.2 0.2 0.2 0.2 0.4 0.3 0.1 0.7 0.9 0.7 0.5 1.5 0.1 0.3 1.4 0.3 4.4 4.5 4.3 5.3 4.5 4.3 5.1 4.5 4.8 4.4 4.8 6.3 3.2 0.0 0.0 13.7 2.9 1.5 2.1 1.9 0.6 1.0 8.6 4.2 1.8 1.5 2.2 1.8 0.0 8.1 1.5 7.9 1.9 3.4 2.0 4.8 30.8 6.8 0.0 0.8 3.3 1.1 398.9 7.6 2.0 9.6 1.3 19.8 10.0 7.2 9.3 0.0 4.3 3.1 0.0 1.9 1.4 8.9 0.6 1.2 5.4 3.7 1.1 4.5 1.0 4.0 7.8 2.7 2.8 0.4 3.4 0.8 2.0 1.6 2.7 0.9 0.0 2.2 7.5 7.2 4.5 1.0 0.3 34.5 3.1 7.6 4.4 1.5 C7orf33 ENSG00000170279 "Chromosome 7 open reading frame 33" Q8WU49 7 148590766-148615860 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "retina: 1.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Early spermatids: 1.1;Extravillous trophoblasts: 7.5;Late spermatids: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 27 "SCLC-21H: 2.6" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (4.09e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 CALHM3 "bA225H22.7, FAM26A" ENSG00000183128 "Calcium homeostasis modulator 3" Q86XJ0 10 103472804-103479240 "Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Taste, Transport" "Ion channel" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.2;Early spermatids: 2.2;Extravillous trophoblasts: 6.7;Late spermatids: 2.0;Syncytiotrophoblasts: 1.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "U-266/84: 14.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA018205 Uncertain Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA018205: AB_2069267" "unprognostic (2.88e-1)" "unprognostic (4.00e-1)" "unprognostic (3.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.87e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (7.42e-3)" "unprognostic (1.44e-1)" "unprognostic (4.89e-2)" "unprognostic (3.07e-1)" "unprognostic (5.05e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.3 2.6 0.3 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 14.3 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.1 0.0 CALR "cC1qR, CRT, FLJ26680, RO, SSA" ENSG00000179218 Calreticulin P27797 19 12938578-12944489 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001513, HPA002242, CAB019952, CAB079775" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 210000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "CAB001513: , CAB019952: AB_2069792, CAB079775: AB_303403, HPA002242: AB_1078384" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.25e-2)" "unprognostic (9.44e-3)" "unprognostic (6.93e-2)" "unprognostic (2.47e-2)" "unprognostic (4.60e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.07e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (5.27e-2)" 295.5 257.6 201.7 352.9 213.4 554.9 218.9 238.0 213.5 256.3 324.0 304.6 287.3 275.8 647.7 338.2 266.7 164.1 303.2 203.5 239.7 296.9 782.3 308.9 230.0 260.4 230.1 272.2 319.7 292.2 284.5 403.3 254.5 277.9 336.7 96.2 299.3 247.2 119.8 189.3 277.2 349.7 237.7 277.3 300.6 165.2 267.3 245.3 702.9 104.7 319.4 252.2 236.6 274.2 1681.4 673.6 832.5 1984.9 1110.8 861.5 724.6 2075.3 1160.8 839.6 1280.4 1044.2 1353.5 1087.2 1960.0 2528.4 1064.5 672.1 906.1 1476.5 800.7 730.0 588.1 894.3 689.0 1619.6 2667.5 3638.5 1171.8 946.8 638.7 1222.3 957.7 1472.5 1507.8 743.1 814.5 536.3 911.7 1222.3 1040.0 2511.9 808.7 952.0 970.1 777.0 770.8 1329.9 1138.3 846.9 312.4 668.4 1438.7 769.8 472.6 789.9 1014.4 1558.9 1460.6 1113.2 666.2 1533.6 938.3 644.3 569.7 985.8 1567.6 1616.3 1258.1 67.5 72.8 39.7 172.8 147.8 119.3 90.0 99.7 130.0 76.3 77.5 73.0 134.4 23.8 103.1 122.7 215.6 83.4 75.8 201.7 213.4 238.0 213.5 203.5 239.7 260.4 230.1 254.5 237.7 267.3 274.2 385.2 147.4 160.7 34.6 385.7 261.7 336.3 217.3 221.4 76.8 214.9 140.8 43.7 163.0 175.4 222.5 127.2 652.9 515.5 524.4 64.6 582.7 27.8 206.3 364.2 305.6 353.6 266.1 14.2 285.5 1717.5 422.5 289.5 348.2 207.4 341.6 312.7 612.4 789.3 35.3 23.8 595.1 93.6 208.8 433.2 30.6 318.7 378.4 213.5 31.9 229.9 316.5 360.5 28.6 31.1 410.2 462.8 311.1 1059.6 426.1 377.8 182.8 147.5 167.7 203.8 224.2 328.9 276.1 306.6 245.5 213.5 964.4 345.8 399.4 471.4 329.6 CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 504.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 2467.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006018 Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 21000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA006018: AB_1845934" "unprognostic (7.22e-3)" "unprognostic (1.16e-3)" "unprognostic (3.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.27e-1)" "unprognostic (9.52e-3)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.75e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.30e-11)" "unprognostic (3.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.60e-5)" 115.8 56.6 20.6 137.9 22.7 22.8 66.2 22.8 28.5 133.5 54.7 97.5 37.6 113.6 61.1 60.4 57.1 92.7 236.9 24.5 23.5 45.1 74.2 68.5 38.8 24.1 22.2 54.8 52.6 85.0 28.8 211.8 24.2 113.0 81.3 19.6 67.7 150.1 82.1 29.9 40.0 328.4 22.3 47.5 62.5 39.8 33.2 31.0 77.1 117.1 45.2 160.1 48.2 26.6 257.8 207.4 486.6 152.7 1348.5 1229.5 270.9 1821.7 1378.1 577.5 770.7 238.6 388.3 100.0 351.5 2467.8 850.4 144.9 258.2 318.2 826.5 80.6 138.2 136.6 283.7 295.0 657.1 187.2 254.3 930.5 223.6 868.3 370.6 904.4 537.3 116.4 237.9 172.8 1131.8 141.0 130.2 95.5 305.2 247.0 197.3 122.9 333.3 164.5 243.5 132.7 44.3 238.2 595.4 481.5 753.1 932.2 106.2 145.6 799.8 1706.6 234.2 1350.8 754.6 306.8 385.7 224.8 1478.6 223.6 1857.2 21.7 38.8 23.5 28.3 41.4 27.9 23.7 19.5 22.0 33.4 16.6 17.1 20.0 4.5 26.2 35.7 32.9 23.4 31.2 20.6 22.7 22.8 28.5 24.5 23.5 24.1 22.2 24.2 22.3 33.2 26.6 67.3 22.4 38.5 25.5 29.9 81.3 68.1 82.0 31.3 28.2 51.7 42.7 247.0 25.8 62.7 25.8 18.8 116.8 25.0 14.4 17.6 69.5 11.4 37.5 186.3 104.0 19.7 42.3 37.7 60.5 504.7 198.8 37.2 72.8 59.6 62.6 113.2 54.2 136.9 28.6 47.0 55.9 22.4 58.9 70.7 9.3 100.3 44.6 120.9 27.2 26.3 32.4 21.6 31.2 32.2 71.5 11.4 118.8 140.9 110.6 12.6 17.7 57.2 12.8 59.2 64.9 162.8 27.1 41.9 30.9 76.9 243.0 30.9 69.7 26.1 90.5 CAPN6 "CalpM, CANPX, CAPNX" ENSG00000077274 "Calpain 6" Q9Y6Q1 X 111245099-111270483 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 212.7;placenta: 83.1;seminal vesicle: 72.4" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 198.5;Syncytiotrophoblasts: 140.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 25.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 10.8;NTERA-2: 16.3;SuSa: 14.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 9.6" HPA040259 Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA040259: " "unprognostic (1.27e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-2)" "unprognostic (5.77e-3)" "unprognostic (2.07e-1)" "unprognostic (9.93e-2)" "unprognostic (8.39e-3)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (9.45e-3)" "unprognostic (5.12e-1)" "unprognostic (6.25e-2)" "unprognostic (7.67e-2)" "unprognostic (6.50e-2)" "unprognostic (5.02e-3)" "unprognostic (2.66e-1)" "unprognostic (6.30e-2)" 2.1 0.0 0.0 7.2 0.0 0.0 12.7 0.0 0.0 11.9 0.0 5.6 1.8 22.5 212.7 2.3 3.2 8.4 0.3 0.0 0.0 11.5 0.3 0.5 2.8 0.0 0.0 2.6 7.5 0.1 0.2 83.1 0.0 10.6 8.6 0.0 14.1 72.4 3.0 1.0 1.7 8.2 0.0 1.7 12.9 2.0 0.0 1.8 1.5 9.0 4.7 3.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 16.3 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.1 0.3 0.4 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 1.2 0.0 0.6 2.0 0.3 7.2 0.0 7.3 0.0 39.9 0.1 0.1 3.9 8.3 0.0 18.0 4.3 0.4 0.0 0.0 0.0 0.7 198.5 12.9 6.6 40.1 0.0 0.0 0.0 0.0 7.6 0.0 0.1 1.2 0.0 0.0 0.3 0.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 22.2 0.1 0.4 0.0 0.2 0.0 0.0 0.0 1.0 0.5 0.1 0.1 0.9 0.0 140.5 0.3 0.9 0.5 0.3 CATSPERZ "C11orf20, DKFZP566E164, TEX40" ENSG00000219435 "Catsper channel auxiliary subunit zeta" Q9NTU4 11 64300358-64304770 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 93 "testis: 586.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.1;Endometrial stromal cells: 12.7;Extravillous trophoblasts: 36.3;Syncytiotrophoblasts: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.8;CACO-2: 13.9;PC-3: 7.9;T-47d: 6.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052822 Approved Nucleoplasm NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA052822: AB_2797245" "unprognostic (1.89e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (8.23e-2)" "unprognostic (2.18e-1)" "unprognostic (1.11e-1)" "unprognostic (5.66e-4)" "unprognostic (5.96e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" 0.4 0.2 4.0 0.1 4.1 0.0 0.6 5.9 6.3 1.0 2.1 0.3 0.1 0.5 0.0 0.4 0.2 0.6 0.1 4.5 3.1 0.5 0.3 0.5 0.1 3.5 3.1 0.1 0.6 0.6 0.1 0.8 3.1 0.8 0.3 0.4 0.2 0.0 0.2 1.2 0.2 0.0 2.6 0.1 0.3 586.3 3.5 0.0 1.0 0.1 0.0 0.3 0.3 4.0 0.0 3.5 0.3 0.1 0.4 0.8 4.8 0.0 0.3 0.0 0.0 13.9 2.8 0.1 0.2 0.1 0.1 3.1 2.6 0.4 0.1 0.0 0.0 1.3 0.1 0.9 0.1 0.0 0.0 0.1 0.2 0.8 0.0 0.0 0.1 0.0 1.4 0.6 0.2 0.6 0.0 0.6 0.9 4.0 7.9 1.5 0.0 1.8 3.9 1.2 0.1 0.8 1.4 0.4 0.2 0.2 6.6 0.3 0.2 0.2 0.0 1.8 0.0 0.4 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 4.1 5.9 6.3 4.5 3.1 3.5 3.1 3.1 2.6 3.5 4.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.5 12.7 0.2 0.0 0.0 0.0 0.5 36.3 0.3 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 0.0 0.1 0.0 0.0 CCDC134 FLJ22349 ENSG00000100147 "Coiled-coil domain containing 134" Q9H6E4 22 41800679-41832164 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003936 Approved "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA003936: AB_1078419" "unprognostic (2.09e-2)" "unprognostic (1.00e-1)" "unprognostic (3.82e-2)" "prognostic favorable (4.09e-4)" "unprognostic (1.73e-1)" "unprognostic (3.85e-2)" "prognostic unfavorable (7.42e-7)" "unprognostic (4.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-2)" "unprognostic (7.32e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.24e-3)" "unprognostic (2.52e-2)" "unprognostic (5.47e-1)" "unprognostic (6.63e-2)" 1.4 10.2 2.2 3.7 2.5 12.6 2.7 9.0 2.4 2.0 2.3 2.6 3.3 1.8 10.5 2.7 3.6 1.3 2.1 2.0 1.9 2.8 2.7 2.4 4.0 3.3 2.7 2.1 3.7 5.0 1.6 2.7 2.8 2.5 2.8 5.8 4.3 2.6 2.8 4.6 3.6 1.8 1.8 2.9 4.2 6.1 3.8 3.7 2.5 2.3 4.6 1.6 1.4 3.5 8.6 6.4 7.3 11.0 4.4 1.3 5.9 7.1 3.8 9.4 11.2 9.7 5.4 8.6 12.1 5.0 7.2 9.5 7.7 5.6 7.0 7.5 11.2 7.5 19.4 7.1 2.3 10.8 8.7 2.2 2.5 11.6 2.5 4.3 4.4 7.5 4.5 16.1 6.1 5.8 7.0 7.3 4.9 11.5 5.4 12.6 11.6 11.0 7.7 7.1 3.6 3.2 13.8 10.3 5.3 4.1 12.6 5.5 3.6 7.5 11.6 4.5 12.0 18.3 11.9 6.8 7.2 6.6 12.2 1.1 3.3 6.9 4.1 5.1 2.9 3.8 2.6 3.5 1.5 2.5 4.7 3.3 1.9 3.6 5.2 1.6 5.2 2.2 2.2 2.5 9.0 2.4 2.0 1.9 3.3 2.7 2.8 1.8 3.8 3.5 1.0 3.2 2.0 6.8 2.5 0.3 1.5 2.4 0.6 1.1 2.1 1.5 0.8 2.8 1.5 3.7 2.1 4.0 3.0 3.3 0.0 5.0 0.8 3.5 1.3 1.7 0.0 2.5 6.0 1.9 18.2 1.7 3.6 2.5 0.0 2.1 0.4 1.6 4.3 0.0 6.4 2.0 0.0 1.0 0.7 0.9 0.6 1.7 1.8 10.3 4.1 0.7 2.1 9.0 5.8 2.6 1.9 0.4 7.9 1.8 3.5 1.4 2.6 2.3 0.0 1.7 2.1 3.7 1.3 1.8 0.0 2.9 2.1 3.3 3.1 1.6 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 723.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 4.0 5.1 4.0 26.0 3.9 52.9 10.0 6.0 4.9 6.3 2.8 22.2 20.9 7.7 5.4 36.0 8.2 4.0 3.0 3.8 4.0 4.8 4.3 3.9 54.5 6.2 4.4 5.0 4.2 5.8 2.6 20.8 6.5 3.8 29.5 5.7 6.5 3.9 3.4 14.5 19.5 14.4 3.5 11.1 10.8 32.9 5.2 76.2 9.3 2.0 67.0 8.4 10.4 4.0 466.0 317.1 423.5 377.1 22.2 37.1 980.2 201.3 150.8 521.3 437.0 471.2 423.9 285.2 239.1 187.6 594.2 284.2 432.4 442.8 577.2 281.4 217.2 181.6 243.2 323.2 6.8 160.5 197.7 16.6 27.7 300.5 207.2 47.7 282.8 274.2 223.5 217.9 430.2 441.4 220.5 184.7 236.7 153.3 199.3 228.4 305.2 288.2 192.6 168.2 212.7 133.5 347.7 160.3 141.9 236.4 306.4 162.5 119.8 114.4 368.5 207.6 510.2 109.2 216.6 399.8 158.8 271.9 358.6 3.1 2.0 1.5 3.2 5.1 4.5 15.4 8.3 7.4 6.0 11.1 2.7 2.6 1.3 8.2 2.4 5.0 17.6 6.2 4.0 3.9 6.0 4.9 3.8 4.0 6.2 4.4 6.5 3.5 5.2 4.0 4.0 0.0 0.5 2.0 11.8 11.5 7.2 32.1 4.6 4.8 9.8 12.3 1.9 1.5 8.8 5.5 2.1 108.2 8.3 9.5 1.9 6.5 110.2 15.2 7.4 6.6 1.2 76.2 2.7 1.4 723.1 18.3 21.4 13.0 2.5 63.0 8.9 3.2 60.2 0.0 2.1 13.8 73.2 12.0 7.2 17.8 3.1 9.7 3.6 1.0 2.7 3.9 2.1 0.5 1.0 2.4 1.5 2.6 24.1 4.5 2.5 5.6 13.1 4.1 6.6 4.9 18.5 74.3 62.2 37.4 7.2 41.5 8.0 11.8 33.4 7.8 CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;placenta: 30.8" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 1756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "BEWO: 293.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" 1.2 5.7 1.9 4.3 2.1 35.8 0.8 2.8 2.7 1.0 0.9 3.9 3.0 1.4 0.6 4.4 0.9 1.0 2.3 2.0 2.5 1.0 0.7 1.1 6.1 2.0 2.1 0.8 1.8 2.8 0.9 30.8 2.0 1.0 4.7 2.0 1.5 1.4 2.1 4.1 2.5 2.2 1.7 4.2 2.1 12.1 2.5 4.5 1.6 1.8 7.8 3.0 1.8 2.3 15.6 31.8 24.3 34.0 5.2 6.0 293.1 24.7 5.3 10.8 13.2 33.0 31.2 13.3 55.9 11.1 14.0 4.9 28.8 12.8 15.2 41.9 17.7 11.2 30.0 34.5 4.1 44.0 28.7 6.2 7.1 14.8 1.9 3.4 13.3 13.2 45.6 5.8 16.8 24.4 24.5 13.0 40.1 36.2 7.2 36.2 28.6 10.1 8.4 24.6 20.5 17.4 35.4 42.7 3.9 35.4 9.5 32.7 8.0 25.0 92.8 14.9 16.9 24.1 18.2 91.6 13.8 5.6 13.7 0.0 0.0 0.0 0.1 0.5 0.3 0.6 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.3 0.1 1.9 2.1 2.8 2.7 2.0 2.5 2.0 2.1 2.0 1.7 2.5 2.3 3.1 0.0 0.6 0.7 4.8 4.8 1.5 0.3 2.2 2.9 8.2 11.3 3.1 0.0 1.4 0.0 0.0 122.4 3.7 3.5 0.0 0.4 14.6 7.5 4.1 1.9 3.0 30.7 2.9 0.7 1756.5 6.0 5.6 20.1 0.0 4.6 1.4 0.2 43.4 3.3 5.1 3.3 0.0 1.0 2.5 3.6 1.2 4.2 1.8 0.0 0.2 1.7 0.0 2.5 1.3 1.4 2.2 2.2 18.4 2.2 1.0 0.4 0.1 1.1 6.6 4.1 3.4 25.0 17.6 8.5 6.0 115.7 4.5 6.9 4.9 3.5 CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 215.6;Hofbauer cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 175.0;U-2197: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" 24.1 19.1 6.6 12.9 4.3 0.7 15.3 0.4 6.5 22.2 15.6 11.4 11.0 20.2 4.3 5.8 10.0 18.2 14.8 4.2 5.7 5.4 11.8 11.6 3.6 5.9 6.7 13.4 15.3 4.3 6.1 26.2 4.1 16.7 4.2 4.6 15.0 9.6 5.0 16.2 8.4 10.8 2.4 9.0 10.9 6.0 7.5 1.6 8.5 2.2 1.6 14.6 13.0 6.7 43.7 44.6 32.5 82.8 57.7 35.0 102.8 47.5 42.0 33.4 30.4 85.3 90.1 0.6 77.7 39.5 64.1 175.0 31.7 39.9 4.4 30.6 76.3 2.8 47.6 47.1 20.9 0.7 51.8 32.7 17.9 28.3 15.4 19.7 38.7 0.0 15.0 0.8 6.2 66.0 0.3 2.3 84.9 8.6 35.9 0.5 47.9 7.0 27.9 53.8 24.9 59.5 40.1 21.2 88.0 23.0 38.1 26.4 49.8 68.6 60.0 231.6 52.5 0.9 0.8 0.8 114.8 3.4 49.4 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 6.6 4.3 0.4 6.5 4.2 5.7 5.9 6.7 4.1 2.4 7.5 6.7 4.4 19.2 8.1 6.5 1.2 15.0 11.5 12.5 8.0 20.2 14.1 11.8 9.1 2.8 17.0 11.0 31.3 11.6 0.2 6.7 1.9 48.6 0.9 14.4 26.7 22.0 9.0 0.0 18.4 19.0 215.6 43.7 14.3 31.6 14.7 41.4 4.6 14.6 82.5 10.1 12.9 13.1 4.1 8.8 30.8 2.2 9.9 14.7 24.9 7.5 4.2 8.4 0.0 5.5 1.7 24.7 15.1 17.3 1.7 12.1 3.1 2.7 5.8 27.5 13.1 7.0 32.1 1.8 4.9 3.4 10.2 12.3 1.4 8.4 10.6 8.4 CDCA4 "FLJ20764, Hepp" ENSG00000170779 "Cell division cycle associated 4" Q9BXL8 14 105009573-105021083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 55.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.2;Cytotrophoblasts: 84.5;Extravillous trophoblasts: 154.5;Spermatogonia: 69.9;Suprabasal keratinocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064971 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA064971: AB_2685395" "unprognostic (2.22e-3)" "unprognostic (1.84e-1)" "unprognostic (2.69e-1)" "unprognostic (9.93e-3)" "unprognostic (1.42e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (4.19e-4)" "prognostic unfavorable (7.94e-4)" "unprognostic (4.20e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (7.50e-2)" "unprognostic (1.24e-2)" 3.9 2.6 1.9 7.4 2.0 55.8 4.2 3.0 2.1 8.7 2.1 4.6 4.7 5.4 1.8 18.6 4.1 2.6 2.7 1.7 1.8 3.4 2.7 3.6 11.6 2.1 1.9 4.1 3.2 1.8 1.7 9.2 2.1 3.8 2.9 1.3 5.5 2.2 1.4 24.7 4.9 3.5 1.9 6.6 3.8 11.6 2.0 14.6 3.3 1.5 8.5 4.2 10.2 2.0 40.6 41.3 46.7 35.6 7.9 13.2 61.1 59.0 18.0 45.2 39.7 50.9 50.2 52.9 31.5 20.9 34.5 63.5 32.9 68.0 27.1 58.2 26.1 33.4 33.9 43.2 9.7 59.8 27.0 9.4 20.8 35.2 32.7 15.1 31.4 45.0 37.5 53.0 32.1 98.8 56.2 40.1 34.8 35.1 94.0 53.6 68.1 19.7 15.9 46.2 27.2 33.5 56.6 22.3 46.8 20.5 44.0 39.8 48.8 39.9 50.5 55.3 79.5 19.5 25.9 54.4 33.5 30.2 67.5 1.1 4.3 10.6 11.9 4.9 14.8 8.4 12.7 16.7 4.7 5.4 7.4 8.9 1.6 12.9 5.6 5.1 11.1 7.0 1.9 2.0 3.0 2.1 1.7 1.8 2.1 1.9 2.1 1.9 2.0 2.0 5.4 0.0 2.2 0.7 7.4 64.2 26.5 36.6 13.1 3.4 8.7 8.3 0.6 0.0 9.0 1.8 0.0 84.5 11.5 4.3 3.9 12.7 8.1 9.0 9.0 10.9 3.0 53.0 1.8 7.0 154.5 10.2 3.1 12.5 28.6 15.1 7.9 2.2 24.3 13.5 1.3 6.6 6.1 5.9 22.6 6.8 8.4 8.4 17.8 2.8 9.3 4.6 9.2 1.0 1.8 12.3 3.3 6.0 11.8 16.1 1.9 1.8 7.7 2.6 6.6 4.6 12.5 43.0 69.9 21.3 67.1 25.9 17.7 3.6 9.5 43.2 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 121.0;Extravillous trophoblasts: 343.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 169.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932, HPA008453, CAB079975" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Plasma membrane, Cytosol" "CAB004364: AB_627243, CAB079975: , HPA007932: AB_1078492, HPA008453: " "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavorable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 13.4 19.8 9.4 9.5 10.2 29.1 14.8 10.9 12.9 17.5 11.5 13.7 13.3 12.1 12.9 37.3 12.5 6.4 12.4 9.5 10.5 18.4 13.6 12.7 4.8 9.7 9.7 11.7 14.1 3.2 18.2 16.2 9.8 13.7 7.4 12.8 18.9 4.8 26.8 25.3 12.2 7.7 9.8 12.6 13.5 30.6 10.0 9.3 13.2 15.0 13.3 16.1 19.9 9.4 42.8 5.9 19.4 30.6 6.4 24.4 169.5 30.9 37.5 46.2 42.9 62.2 64.5 3.7 36.4 36.8 34.2 65.3 10.8 31.3 40.6 9.0 3.1 8.6 21.4 25.9 32.8 17.9 33.8 7.1 61.3 1.8 46.0 24.5 32.5 22.3 16.3 16.1 13.3 33.3 9.4 51.7 20.7 2.8 25.4 12.3 0.7 27.1 42.6 25.4 8.6 17.5 11.6 50.4 42.4 28.1 44.9 39.3 7.4 17.1 27.4 33.1 18.2 14.4 30.4 16.5 31.4 10.2 15.5 27.9 7.9 16.2 5.3 8.9 7.9 10.6 7.8 10.6 7.3 14.5 5.9 6.4 8.2 8.6 4.7 8.9 10.5 6.1 9.4 10.2 10.9 12.9 9.5 10.5 9.7 9.7 9.8 9.8 10.0 9.4 12.2 16.0 13.2 10.7 7.8 57.7 21.4 32.9 15.4 6.4 12.3 14.7 11.3 10.0 20.2 5.5 12.5 121.0 11.7 10.2 15.6 27.8 26.8 33.1 10.7 11.6 3.0 9.9 17.6 21.6 343.6 13.0 9.7 27.2 15.8 7.4 7.1 6.7 24.0 1.7 13.7 12.3 20.3 8.5 6.0 7.9 7.5 8.5 7.2 11.2 11.6 10.4 15.5 8.0 11.9 29.3 16.2 7.2 5.8 28.2 12.3 29.3 42.4 8.7 26.3 10.0 12.5 70.1 18.6 15.9 41.9 64.6 11.4 6.8 13.2 29.8 CERS5 "FLJ25304, LASS5, MGC45411, Trh4" ENSG00000139624 "Ceramide synthase 5" Q8N5B7 12 50129289-50167533 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006780, HPA026589" Approved Approved "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA006780: , HPA026589: AB_1852727" "unprognostic (1.59e-2)" "unprognostic (9.83e-2)" "unprognostic (5.17e-2)" "unprognostic (3.64e-2)" "unprognostic (3.02e-1)" "unprognostic (2.49e-3)" "prognostic unfavorable (4.63e-5)" "unprognostic (5.56e-2)" "unprognostic (1.65e-2)" "unprognostic (9.26e-2)" "unprognostic (1.88e-3)" "unprognostic (5.67e-2)" "prognostic unfavorable (9.33e-11)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "prognostic favorable (5.76e-5)" "unprognostic (3.26e-1)" 26.2 22.3 27.6 4.8 28.5 5.1 26.6 29.7 48.1 37.2 27.4 24.1 3.0 30.5 12.0 24.0 28.2 6.9 16.2 27.7 29.6 44.1 14.2 22.9 6.1 28.3 28.6 35.1 22.9 9.1 42.3 5.5 28.9 31.2 2.9 5.5 21.5 3.5 5.5 34.1 20.6 4.6 27.5 29.2 21.6 13.8 29.5 7.6 24.8 2.3 3.7 29.5 29.2 29.0 12.1 13.2 17.1 3.5 6.5 3.9 10.6 23.3 6.6 8.0 7.4 36.2 13.9 10.6 20.2 24.4 7.7 7.9 6.1 4.4 6.7 23.4 12.7 6.1 11.2 23.2 16.5 8.0 12.4 19.4 13.9 11.6 6.3 18.7 11.9 10.0 6.1 10.8 8.6 18.7 15.4 45.6 8.2 4.1 7.0 10.7 4.3 12.7 28.7 17.7 5.2 6.9 10.3 9.4 33.6 10.7 13.0 9.9 10.6 17.6 10.2 11.6 8.0 8.1 14.3 11.6 12.8 5.9 8.4 36.3 23.0 42.4 37.0 37.4 28.7 22.0 28.6 28.6 26.8 30.6 20.1 28.9 41.2 39.6 55.1 36.0 37.1 37.1 27.6 28.5 29.7 48.1 27.7 29.6 28.3 28.6 28.9 27.5 29.5 29.0 14.9 19.2 18.4 22.5 17.7 17.3 20.9 29.1 12.0 41.0 11.5 9.8 6.8 14.3 16.5 14.7 20.9 32.9 23.1 8.1 7.9 21.2 0.9 7.7 16.7 17.2 15.6 9.1 47.7 14.0 65.2 21.9 10.7 11.8 15.2 15.0 18.2 4.6 19.0 32.0 56.1 7.9 28.5 17.9 18.3 2.2 16.8 14.3 12.4 20.6 26.6 21.3 24.7 40.2 34.8 19.0 6.8 17.3 12.7 15.5 14.2 7.7 8.6 44.3 32.9 18.2 20.8 7.6 8.1 9.3 14.3 33.7 22.1 15.7 6.7 14.7 CLDN19 ENSG00000164007 "Claudin 19" Q8N6F1 1 42733093-42740254 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "choroid plexus: 19.8;kidney: 39.1;placenta: 9.8" "Cell type enriched" "Detected in some" 6 "Extravillous trophoblasts: 221.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 3.0;Hep G2: 6.3;SuSa: 3.5" "Region enhanced" "Detected in many" "olfactory bulb: 5.4" "Region enriched" "Detected in many" 6 "spinal cord: 41.8" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (6.23e-4)" "unprognostic (1.80e-1)" "unprognostic (1.85e-6)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-1)" "unprognostic (9.45e-2)" "unprognostic (1.95e-1)" "unprognostic (2.68e-1)" "unprognostic (7.22e-2)" "unprognostic (8.76e-3)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.29e-3)" 0.8 0.1 0.1 0.0 0.1 0.1 1.1 0.4 0.5 0.0 19.8 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.1 1.3 0.0 39.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.8 0.6 0.3 0.0 0.0 0.8 0.7 0.2 0.5 0.1 0.0 0.1 0.0 0.3 0.0 0.1 1.6 0.0 0.9 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.5 1.3 0.0 0.1 0.0 0.6 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.3 0.2 8.3 0.3 0.0 0.6 12.9 0.0 12.5 0.0 0.0 33.2 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 221.6 0.7 0.0 0.2 0.0 0.0 0.7 0.0 5.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.0 12.4 0.1 0.2 0.1 0.0 CLDN6 ENSG00000184697 "Claudin 6" P56747 16 3014712-3020071 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.1;pancreas: 1.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 35.8;Ductal cells: 23.7;Extravillous trophoblasts: 144.2;Syncytiotrophoblasts: 44.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 73.6;testis cancer: 112.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 477.8;CACO-2: 134.6;NTERA-2: 443.1;SuSa: 328.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (2.59e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.42e-6)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "unprognostic (6.08e-2)" "unprognostic (1.92e-1)" "unprognostic (5.50e-4)" "unprognostic (1.02e-2)" "unprognostic (5.88e-1)" "unprognostic (1.98e-2)" "unprognostic (7.66e-4)" "unprognostic (1.79e-3)" "unprognostic (1.02e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (1.78e-4)" 0.0 0.2 0.7 0.0 0.9 0.1 0.0 1.1 0.7 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.6 0.3 0.8 0.0 0.2 0.0 0.4 0.4 0.0 1.0 0.0 0.3 0.7 0.4 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.9 0.3 0.7 0.0 477.8 0.1 0.0 0.0 0.0 134.6 0.7 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.7 0.0 0.0 0.2 0.1 60.2 0.0 0.1 0.1 0.1 0.6 0.1 0.0 0.2 0.0 0.0 0.4 0.2 0.1 1.0 0.0 0.3 443.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.4 0.6 0.6 0.0 328.9 0.2 0.1 0.5 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.9 1.1 0.7 0.6 0.3 0.4 0.4 0.4 0.1 0.3 0.4 0.2 3.2 0.0 0.0 0.0 0.9 1.2 0.0 0.0 0.0 0.8 1.3 0.3 0.0 0.1 0.0 0.0 35.8 0.0 0.0 0.0 23.7 0.2 1.4 0.1 0.2 0.0 0.0 0.1 0.0 144.2 0.6 0.0 1.6 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 1.8 0.4 0.6 5.4 0.0 0.4 44.1 0.2 0.0 0.1 0.2 CLEC1A "CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.2;placenta: 49.0" "Cell type enhanced" "Detected in some" "Adipocytes: 51.4;Cytotrophoblasts: 51.5;Endothelial cells: 38.1;Extravillous trophoblasts: 61.7;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 21.3;HUVEC TERT2: 18.3;SuSa: 5.6;U-266/70: 4.9;U-266/84: 11.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" 16.2 3.2 4.4 4.1 4.2 0.4 14.8 6.6 5.6 11.4 4.1 4.3 1.5 6.8 2.7 3.8 9.2 5.7 9.0 3.9 3.8 5.8 2.9 29.8 5.9 4.8 4.5 5.4 2.3 1.6 3.7 49.0 4.7 6.3 2.0 0.6 2.9 2.4 3.9 4.1 4.4 8.7 4.3 8.0 3.7 2.1 5.1 50.2 7.6 4.4 3.5 6.1 8.6 4.1 0.0 0.0 0.3 0.3 0.2 0.2 21.3 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.9 0.0 0.0 0.0 0.4 3.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.4 0.0 0.3 0.3 0.0 5.6 0.0 0.0 1.4 0.0 0.2 0.2 0.0 4.9 11.5 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 4.4 4.2 6.6 5.6 3.9 3.8 4.8 4.5 4.7 4.3 5.1 4.1 51.4 0.0 0.5 0.0 0.5 2.2 0.1 0.0 1.2 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 51.5 0.2 0.0 0.0 0.0 0.4 0.0 0.1 38.1 0.0 0.0 0.0 0.0 61.7 1.2 0.0 0.0 0.0 0.0 16.8 0.2 5.0 0.0 0.0 0.0 0.0 4.7 14.1 0.6 7.5 4.0 3.6 11.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.9 4.0 2.9 0.3 1.6 52.1 0.6 0.3 0.0 0.5 CNPY2 "HP10390, TMEM4, ZSIG9" ENSG00000257727 "Canopy FGF signaling regulator 2" Q9Y2B0 12 56309842-56316119 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 475.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038465, HPA038466" Supported Supported Cytosol "Intracellular and membrane" NA NA 220000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA038465: AB_10967609, HPA038466: AB_10672646" "unprognostic (3.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.49e-1)" "unprognostic (2.46e-2)" "unprognostic (4.33e-2)" "unprognostic (2.20e-1)" "unprognostic (1.17e-3)" "unprognostic (1.46e-1)" "unprognostic (7.68e-2)" "unprognostic (2.04e-3)" "prognostic favorable (8.37e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.32e-8)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (5.06e-2)" 36.7 52.5 28.4 25.8 30.3 24.7 41.8 30.0 30.7 43.3 38.1 36.6 30.9 35.6 74.4 34.1 38.1 25.4 28.4 27.7 31.8 37.8 75.7 30.5 22.0 31.1 29.0 42.7 58.9 47.3 66.8 40.8 28.9 35.3 38.5 18.8 53.1 36.4 21.2 23.5 34.6 24.9 30.5 35.1 42.1 20.0 29.8 27.0 44.7 18.6 26.6 32.9 31.1 32.2 50.6 75.5 76.0 62.8 186.0 64.0 120.7 51.0 117.4 108.7 76.5 116.0 87.9 51.2 95.0 132.4 53.2 72.4 92.3 62.8 68.7 51.3 57.5 49.9 106.1 121.8 83.6 94.9 60.4 76.5 80.5 89.9 106.6 165.5 91.1 59.0 73.8 113.5 81.3 76.2 58.2 105.3 72.6 107.5 109.5 65.1 58.3 84.9 90.1 47.6 67.9 41.7 85.1 86.8 93.6 92.7 78.0 176.8 41.2 42.7 33.6 52.2 74.7 58.4 88.2 41.5 90.2 88.2 70.9 56.8 66.5 36.8 65.8 56.9 77.8 73.2 70.7 71.7 69.5 66.2 70.4 67.0 9.8 70.9 34.6 71.3 68.4 76.4 28.4 30.3 30.0 30.7 27.7 31.8 31.1 29.0 28.9 30.5 29.8 32.2 76.2 48.1 93.7 17.3 79.2 54.8 75.2 129.9 17.1 80.5 178.6 191.6 9.8 140.2 95.2 101.2 64.6 248.3 74.0 80.2 52.8 191.8 40.2 54.7 59.9 72.6 141.9 34.3 31.8 168.7 475.0 77.5 31.1 53.1 91.3 60.7 98.9 185.8 147.4 58.9 32.4 187.2 103.7 59.2 55.8 17.7 103.8 47.8 122.7 13.1 99.7 88.6 125.7 40.2 45.6 162.4 114.1 100.1 68.2 107.4 176.6 145.5 74.1 92.2 26.3 59.1 82.8 72.4 44.0 20.0 53.8 236.4 60.5 78.2 177.8 71.0 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 643.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Cytotrophoblasts: 122.3;Extravillous trophoblasts: 153.0;Granulosa cells: 54.2;Syncytiotrophoblasts: 67.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.1" "Group enriched" "Detected in many" 8 "BEWO: 592.6;SuSa: 739.0" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" 0.2 0.2 0.6 0.3 0.7 0.3 5.8 0.8 1.6 43.1 0.8 2.9 1.1 2.8 1.7 19.8 1.3 0.5 0.1 0.6 0.5 21.3 0.2 0.9 0.1 0.7 0.6 0.2 2.1 1.4 1.5 16.8 0.6 0.7 3.2 17.2 9.4 0.1 0.7 52.5 0.4 0.8 0.5 0.2 2.8 65.8 0.6 643.6 1.3 0.1 6.0 0.4 20.1 1.0 37.1 5.2 12.1 33.1 0.6 0.0 592.6 0.5 0.0 7.1 4.7 81.0 37.7 0.3 2.8 0.5 50.5 67.2 58.8 43.9 9.7 0.1 4.4 0.8 1.9 3.1 0.2 0.1 3.3 0.0 9.2 1.5 0.8 0.9 2.4 8.5 0.5 0.2 14.4 15.2 0.9 0.3 76.2 78.9 10.7 0.0 27.3 0.1 11.4 3.7 2.4 3.6 39.1 13.1 13.2 739.0 21.1 3.2 0.0 1.0 23.6 0.2 3.5 5.7 20.6 0.8 1.6 0.4 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.0 0.2 3.3 0.0 15.1 0.0 0.1 0.6 0.7 0.8 1.6 0.6 0.5 0.7 0.6 0.6 0.5 0.6 1.0 0.9 0.0 1.1 0.3 0.9 30.3 13.0 63.7 19.9 4.6 13.1 9.9 1.3 0.0 17.4 1.8 10.4 122.3 6.9 4.7 1.9 1.8 2.6 15.0 2.9 1.8 1.8 0.0 0.6 0.8 153.0 3.2 0.0 24.0 0.0 54.2 0.4 0.0 13.6 0.0 0.9 1.5 10.2 0.8 3.0 8.2 4.1 2.4 0.0 0.0 0.2 6.5 0.0 0.0 3.5 0.5 10.5 1.2 0.0 8.1 0.1 22.1 4.2 36.6 6.6 1.4 3.6 46.7 33.7 8.2 11.9 67.3 0.5 0.7 4.2 8.4 CYB5R1 "humb5R2, NQO3A2" ENSG00000159348 "Cytochrome b5 reductase 1" Q9UHQ9 1 202961873-202967275 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 605.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 187.2;Extravillous trophoblasts: 196.5;Syncytiotrophoblasts: 293.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 187.3;hTCEpi: 188.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010641, HPA014147" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria Cytosol "HPA010641: AB_1078600, HPA014147: AB_1847370" "unprognostic (6.36e-2)" "unprognostic (8.51e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.86e-2)" "unprognostic (4.34e-2)" "unprognostic (8.46e-2)" "unprognostic (1.28e-1)" "unprognostic (4.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.73e-2)" "unprognostic (2.33e-1)" "unprognostic (6.14e-2)" "unprognostic (2.37e-3)" "unprognostic (1.69e-1)" 38.6 57.3 37.4 23.0 38.8 19.7 43.7 41.1 40.5 49.7 57.3 35.7 19.3 41.2 131.4 61.6 68.2 27.2 154.8 38.3 48.0 64.5 50.2 44.0 25.2 45.4 49.4 41.7 45.1 82.9 46.1 66.6 55.7 41.1 21.2 34.3 56.9 40.0 605.2 123.8 25.7 37.5 39.9 39.1 92.8 50.7 41.4 40.1 40.5 308.0 38.8 52.7 45.8 43.6 34.8 21.3 18.3 37.7 166.0 37.9 178.5 68.3 63.4 43.2 38.4 17.5 39.9 21.5 56.5 68.1 24.0 187.3 14.9 58.0 28.2 31.2 37.8 12.4 24.0 20.4 59.7 10.5 29.6 61.2 188.3 47.5 25.8 36.4 28.9 25.8 37.0 37.6 157.8 40.4 13.6 9.5 12.1 31.0 40.1 21.9 87.6 45.7 41.1 40.8 15.7 19.1 38.0 124.0 57.4 39.4 57.7 23.4 28.5 49.0 20.8 18.7 38.3 34.9 44.5 10.0 53.6 16.2 37.1 24.4 56.7 46.6 27.4 42.6 36.3 23.4 30.9 28.9 37.6 35.0 41.9 29.6 46.0 32.2 29.4 25.9 34.2 52.6 37.4 38.8 41.1 40.5 38.3 48.0 45.4 49.4 55.7 39.9 41.4 43.6 33.0 22.4 29.8 10.1 15.5 187.2 38.5 89.5 42.1 21.0 46.1 41.9 119.3 37.1 60.5 29.5 29.2 171.1 15.8 10.6 7.9 38.3 5.0 58.7 17.3 30.0 19.2 30.7 8.9 48.3 196.5 28.9 31.6 34.9 28.5 13.6 32.9 44.6 63.5 10.1 11.3 10.8 105.8 45.4 29.7 8.6 29.8 39.5 64.0 8.4 20.9 65.9 11.3 11.6 8.1 72.8 11.3 31.2 12.5 25.8 16.0 38.9 75.9 35.0 13.1 49.1 30.0 23.0 4.3 40.6 157.4 293.5 19.5 27.9 14.7 48.2 DDX59 "DKFZP564B1023, ZNHIT5" ENSG00000118197 "DEAD-box helicase 59" Q5T1V6 1 200623896-200669907 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047166 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 50: Non-specific - Ribosome" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Actin filaments" "HPA047166: AB_2679966" "unprognostic (1.99e-1)" "unprognostic (1.60e-1)" "unprognostic (3.44e-2)" "unprognostic (4.87e-2)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (4.83e-2)" "unprognostic (3.40e-3)" "unprognostic (2.43e-3)" "unprognostic (4.16e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (6.66e-2)" "unprognostic (5.98e-2)" 15.4 16.1 13.5 14.2 15.4 33.1 26.5 17.1 18.8 16.2 15.6 14.2 10.2 17.6 20.0 13.5 15.5 12.2 13.3 14.0 14.7 16.4 17.8 14.5 17.0 16.0 15.0 17.6 18.8 15.0 11.3 18.7 17.3 15.2 15.0 17.4 14.4 13.2 32.8 26.2 14.3 14.1 16.3 22.4 12.1 11.0 15.1 22.0 16.2 20.1 16.9 15.0 14.7 17.8 17.5 20.1 22.6 19.0 10.1 17.4 49.9 19.1 17.4 20.5 16.5 6.3 20.2 17.9 9.5 15.7 16.4 16.2 13.0 19.4 14.5 56.8 13.3 13.6 26.4 18.6 20.2 19.5 24.0 18.8 29.1 15.4 41.7 16.7 15.9 24.8 17.4 25.9 20.1 20.0 12.0 29.0 23.8 10.5 16.3 10.1 15.5 34.7 21.9 19.8 13.8 35.7 30.8 31.7 35.6 28.8 27.3 27.3 14.4 17.1 9.5 16.8 20.0 19.5 27.2 23.5 16.3 12.2 30.0 33.3 12.4 24.7 15.1 11.1 12.4 14.9 12.5 13.8 10.6 14.8 12.7 11.8 22.9 16.4 22.0 11.8 19.8 10.2 13.5 15.4 17.1 18.8 14.0 14.7 16.0 15.0 17.3 16.3 15.1 17.8 22.5 19.2 20.1 8.8 19.9 16.2 13.1 16.1 24.5 4.3 10.0 13.2 18.4 7.2 10.6 7.3 2.1 22.2 14.6 9.8 15.6 8.8 2.4 14.6 13.3 16.7 1.2 10.5 4.5 8.2 28.0 14.9 6.6 12.8 20.8 7.1 14.3 7.3 13.0 6.7 6.1 11.0 14.2 12.0 13.0 1.1 8.1 16.1 5.4 8.4 18.5 8.3 25.7 19.1 10.3 8.8 7.9 13.5 13.1 12.0 8.0 11.6 10.8 6.7 0.0 22.8 15.7 14.2 20.0 12.9 15.6 43.8 18.9 9.3 8.5 11.1 DFFB "CAD, CPAN, DFF-40, DFF40" ENSG00000169598 "DNA fragmentation factor subunit beta" O76075 1 3857267-3885429 "Predicted intracellular proteins" Apoptosis "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.9;Extravillous trophoblasts: 29.5;Oligodendrocytes: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004328, HPA052904" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "CAB004328: AB_626776, HPA052904: AB_2681985" "unprognostic (2.98e-1)" "unprognostic (5.09e-2)" "unprognostic (4.37e-2)" "unprognostic (1.52e-3)" "unprognostic (6.12e-2)" "unprognostic (1.83e-2)" "unprognostic (1.38e-2)" "unprognostic (1.28e-3)" "unprognostic (2.66e-2)" "unprognostic (1.79e-1)" "unprognostic (7.82e-3)" "unprognostic (4.07e-1)" "unprognostic (1.90e-2)" "unprognostic (9.86e-3)" "unprognostic (3.39e-1)" "unprognostic (2.27e-1)" "prognostic favorable (6.29e-5)" 1.3 1.1 0.6 1.2 0.7 1.0 1.1 0.5 0.9 1.7 0.0 1.5 4.6 1.6 0.0 0.8 1.3 1.4 0.7 0.7 0.5 0.7 0.4 1.0 1.6 1.5 0.9 1.7 2.4 0.5 0.6 1.3 0.7 0.8 0.8 0.2 1.3 0.7 0.5 0.6 2.0 0.4 0.4 1.9 1.2 0.4 0.6 1.2 0.8 0.5 0.9 1.4 1.0 1.5 3.2 3.3 2.0 4.7 0.6 1.6 1.1 2.7 1.2 4.1 2.8 2.6 2.8 2.6 2.2 0.5 0.8 1.7 0.7 3.2 0.2 9.0 9.7 10.7 1.2 3.2 3.3 8.7 7.9 0.4 0.8 2.4 1.9 0.8 4.1 7.5 7.4 1.6 0.1 1.8 6.1 4.8 2.2 3.9 7.4 4.9 1.2 4.4 1.3 0.6 3.3 5.1 2.3 6.5 10.7 0.0 1.1 3.8 4.1 1.5 1.1 6.5 2.5 2.9 4.6 5.4 1.2 9.0 2.0 3.6 3.7 5.0 3.4 3.8 2.0 2.1 2.5 3.1 5.1 1.0 2.1 3.2 1.2 2.3 7.4 0.0 4.7 2.9 0.6 0.7 0.5 0.9 0.7 0.5 1.5 0.9 0.7 0.4 0.6 1.5 3.3 3.2 4.6 4.2 3.0 0.6 1.0 1.4 1.8 5.5 1.9 2.7 1.3 2.8 1.7 1.8 45.9 3.5 7.3 1.6 1.9 1.9 1.4 3.3 4.6 3.1 2.4 2.5 17.0 1.6 29.5 3.2 1.5 2.5 0.0 4.6 2.5 1.8 2.9 15.2 18.0 4.2 0.0 5.4 1.4 1.2 1.2 3.7 0.0 8.4 2.5 3.9 15.5 5.5 22.7 1.8 1.5 4.9 3.1 0.6 5.0 2.4 1.1 17.9 0.0 1.7 3.2 1.7 2.5 1.7 0.3 1.4 6.0 3.3 4.4 0.7 DIO2 "SelY, TXDI2" ENSG00000211448 "Iodothyronine deiodinase 2" Q92813 14 80197526-80387757 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 163.9;thyroid gland: 355.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 150.7;Endometrial stromal cells: 158.3;Extravillous trophoblasts: 523.3;Muller glia cells: 246.4" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 80.8;fHDF/TERT166: 41.8;HeLa: 95.4;HHSteC: 44.2;SiHa: 168.1;SK-BR-3: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048002 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA048002: AB_2680230" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.67e-4)" "prognostic favorable (4.62e-6)" "unprognostic (2.76e-1)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (2.07e-1)" "unprognostic (8.78e-2)" "unprognostic (3.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-3)" "unprognostic (5.08e-2)" "unprognostic (3.43e-1)" "unprognostic (8.40e-2)" "unprognostic (7.15e-2)" 1.5 3.0 18.0 0.6 15.3 0.1 15.3 15.0 24.6 163.9 5.9 1.3 1.3 40.2 0.5 58.9 0.7 5.1 11.9 17.1 13.0 5.0 0.1 1.6 0.8 13.6 19.2 0.2 1.8 6.6 31.6 14.5 17.4 9.0 1.7 7.4 33.3 30.4 6.5 7.1 1.5 4.5 5.5 0.6 5.3 4.7 13.3 1.2 355.8 70.7 33.1 6.0 25.0 16.6 0.2 9.5 0.0 0.0 0.5 1.4 0.3 80.8 16.6 6.2 0.9 0.0 0.3 0.2 0.2 41.8 0.3 1.7 2.9 0.0 6.1 0.0 0.2 0.0 95.4 0.0 44.2 0.0 0.2 5.1 0.0 1.2 0.0 3.9 1.4 0.0 0.0 0.8 0.5 1.9 0.1 0.1 1.7 0.0 0.5 0.8 3.9 0.1 0.0 0.8 0.0 0.2 168.1 35.3 0.3 7.1 0.1 0.0 0.8 0.3 7.0 17.4 20.1 2.8 0.0 0.0 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 15.3 15.0 24.6 17.1 13.0 13.6 19.2 17.4 5.5 13.3 16.6 0.1 0.0 0.5 52.9 0.3 2.9 0.1 0.0 2.2 3.3 150.7 34.4 1.9 0.0 0.0 0.0 0.0 4.8 0.5 0.2 0.0 0.0 29.5 14.2 158.3 2.3 0.0 0.0 1.0 0.0 523.3 24.6 0.0 15.6 0.0 0.1 0.7 0.2 9.2 1.7 1.0 0.5 0.0 1.3 5.7 12.5 3.4 1.3 5.4 4.7 0.0 246.4 0.0 8.5 1.4 1.0 0.0 4.1 0.3 0.3 0.0 0.0 0.0 7.8 0.0 69.1 6.5 9.7 0.7 8.9 3.0 28.2 1.7 0.9 0.1 0.1 DLX3 ENSG00000064195 "Distal-less homeobox 3" O60479 17 49990005-49995224 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 53.8" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 35.9;Extravillous trophoblasts: 69.1;Syncytiotrophoblasts: 96.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 135.9;SK-BR-3: 44.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA031164 Approved Nucleoplasm,Cytosol NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA031164: AB_10603565" "unprognostic (1.20e-1)" "unprognostic (1.75e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.61e-4)" "unprognostic (1.95e-1)" "unprognostic (2.63e-2)" "unprognostic (1.02e-1)" "unprognostic (2.55e-1)" "unprognostic (1.77e-2)" "unprognostic (7.98e-2)" "unprognostic (1.44e-5)" "unprognostic (3.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" 0.5 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.5 1.9 0.1 0.1 0.0 0.0 0.3 3.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.4 0.0 0.4 0.9 0.3 0.2 0.6 0.2 7.4 0.4 0.5 0.0 0.0 1.5 0.7 0.0 53.8 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 1.8 0.0 3.0 0.4 4.0 0.0 0.5 0.0 0.0 2.6 0.8 0.6 135.9 0.1 0.0 0.0 0.0 1.3 0.2 0.0 1.5 1.6 0.0 17.1 7.1 0.1 0.0 0.0 0.3 0.0 4.2 0.2 0.0 0.0 0.5 0.0 12.7 0.4 0.0 0.0 0.0 0.9 0.1 0.0 1.7 4.1 0.0 0.4 0.5 0.3 0.6 0.0 0.0 0.3 0.0 1.9 15.1 0.1 1.5 44.1 0.0 9.1 17.5 0.9 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.4 0.9 0.4 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 5.0 0.4 1.1 9.1 0.0 3.5 5.3 2.0 0.0 0.2 0.0 0.0 35.9 0.0 0.0 0.0 0.6 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.0 69.1 0.7 0.0 0.2 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.1 1.0 0.0 2.0 3.4 5.1 96.0 0.1 0.0 0.0 0.5 DLX4 "BP1, DLX7, DLX8, DLX9" ENSG00000108813 "Distal-less homeobox 4" Q92988 17 49968970-49974959 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 3.7;skin 1: 3.0" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 77.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 22.9;CACO-2: 16.8;GAMG: 15.3;HAP1: 11.2;K-562: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059933 Uncertain Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA059933: AB_2684169" "unprognostic (8.12e-2)" "unprognostic (2.48e-1)" "unprognostic (1.26e-2)" "unprognostic (2.29e-3)" "unprognostic (7.49e-2)" "unprognostic (2.71e-1)" "unprognostic (9.35e-3)" "unprognostic (2.85e-2)" "unprognostic (8.73e-2)" "unprognostic (5.93e-2)" "unprognostic (1.29e-2)" "unprognostic (4.34e-2)" "unprognostic (2.88e-13)" "unprognostic (8.79e-3)" "unprognostic (2.77e-1)" "unprognostic (5.00e-2)" "unprognostic (6.86e-2)" 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.2 0.7 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.6 0.2 0.2 0.8 0.0 0.3 0.2 0.1 3.7 0.5 0.2 0.1 0.0 1.1 0.2 0.0 3.0 0.2 0.0 0.2 0.4 0.1 0.3 0.2 0.1 0.3 0.0 0.5 0.2 0.5 0.2 0.5 1.4 0.0 0.1 0.1 0.0 22.9 0.1 0.1 0.1 0.3 16.8 1.0 0.7 3.3 0.3 15.3 2.3 11.2 0.4 0.1 4.5 5.9 0.4 5.7 1.7 0.0 0.9 3.7 0.0 2.8 0.1 0.0 0.2 0.0 3.5 13.5 0.0 0.0 2.9 0.4 6.0 0.2 3.1 0.0 0.0 5.1 0.6 0.1 0.8 1.9 0.1 0.4 1.9 1.1 3.4 4.1 4.0 0.0 0.0 1.0 0.2 0.0 0.9 0.2 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.2 0.1 0.6 0.2 0.1 0.2 0.8 0.5 0.2 0.2 0.2 0.0 6.4 0.0 0.0 0.2 2.5 0.4 1.0 2.2 0.0 0.5 0.3 1.9 0.0 0.1 0.0 0.0 12.7 0.1 0.1 0.0 0.3 0.1 1.5 0.1 0.2 0.0 0.0 0.3 0.2 77.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 1.0 1.1 0.4 0.6 16.8 0.1 0.2 0.2 0.3 DLX6 ENSG00000006377 "Distal-less homeobox 6" P56179 7 97005553-97011040 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.3;testis: 5.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 32.9;Early spermatids: 22.6;Endometrial ciliated cells: 37.3;Extravillous trophoblasts: 70.4;Glandular and luminal cells: 27.5;Syncytiotrophoblasts: 17.4" "Cancer enriched" "Detected in many" 8 "endometrial cancer: 12.5" "Region enhanced" "Detected in many" "basal ganglia: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 33.4;HAP1: 15.3;SH-SY5Y: 11.0;SuSa: 19.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 27.0" "HPA030608, HPA061460" Uncertain Approved "Nuclear bodies" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear bodies" "HPA030608: AB_10600867, HPA061460: AB_2684529" "unprognostic (7.50e-2)" "unprognostic (1.91e-1)" "unprognostic (5.19e-2)" "unprognostic (8.06e-2)" "unprognostic (8.16e-2)" "unprognostic (3.05e-1)" "unprognostic (4.32e-2)" "unprognostic (2.51e-1)" "unprognostic (2.86e-1)" "unprognostic (6.56e-2)" "unprognostic (8.09e-2)" "unprognostic (1.12e-7)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (5.58e-2)" "unprognostic (8.12e-2)" 0.4 0.0 2.1 0.0 7.3 0.3 0.1 0.0 4.3 2.0 0.0 0.2 0.0 2.5 0.8 0.0 0.4 0.0 0.1 0.8 4.7 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 3.0 0.0 0.3 0.0 0.0 1.1 0.9 0.1 1.5 0.0 0.2 0.0 0.1 0.0 5.5 1.2 0.3 0.4 0.1 0.2 0.3 0.2 0.4 0.0 0.0 0.0 10.1 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 6.1 0.0 0.0 1.9 15.3 0.0 0.0 0.0 3.9 0.0 5.9 7.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 2.6 1.6 0.0 0.0 0.0 0.0 2.2 7.3 11.0 1.0 0.0 0.3 19.3 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.9 1.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 7.3 0.0 4.3 0.8 4.7 0.0 0.0 0.0 0.0 1.2 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 32.9 0.1 0.0 0.0 0.0 22.6 37.3 2.2 0.2 0.0 0.0 0.0 0.0 70.4 0.2 0.0 27.5 0.0 0.0 0.0 0.0 3.3 0.0 8.0 0.0 0.0 0.0 0.0 3.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.8 6.8 10.2 0.0 0.0 17.4 0.3 0.0 0.0 0.1 DPPA2 "CT100, PESCRG1" ENSG00000163530 "Developmental pluripotency associated 2" Q7Z7J5 3 109293788-109316517 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 3.3" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 12.0;Spermatogonia: 14.5" "Cancer enriched" "Detected in some" 41 "testis cancer: 35.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 6.0;EFO-21: 11.4;SuSa: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036134 Uncertain Approved Nucleoplasm NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA036134: AB_10601547" "unprognostic (2.23e-1)" "unprognostic (2.79e-1)" "unprognostic (1.81e-2)" "unprognostic (3.50e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 6.5 0.4 0.0 0.1 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 14.5 0.0 0.0 1.6 0.0 0.1 0.0 0.0 DYNC2I2 "bA216B9.3, CFAP133, DIC5, FAP133, MGC20486, WDR34" ENSG00000119333 "Dynein 2 intermediate chain 2" Q96EX3 9 128633653-128656847 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.4;Cytotrophoblasts: 89.8;Extravillous trophoblasts: 95.3;Hofbauer cells: 21.9;Syncytiotrophoblasts: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 35.8;naive B-cell: 52.9" "Lineage enriched" "Detected in all" 5 "B-cells: 52.9" "Cell line enhanced" "Detected in all" "MCF7: 432.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040764, HPA041091" Approved Approved Cytosol NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA040764: AB_10795625, HPA041091: AB_10796237" "unprognostic (1.45e-1)" "prognostic favorable (1.63e-4)" "unprognostic (2.55e-1)" "prognostic favorable (7.01e-5)" "unprognostic (2.27e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (8.79e-4)" "unprognostic (6.04e-2)" "unprognostic (4.39e-1)" "unprognostic (3.65e-1)" "unprognostic (8.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-3)" "unprognostic (2.06e-2)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" 14.4 49.9 15.7 11.4 15.4 33.2 20.1 14.3 20.1 28.2 30.5 26.7 22.2 22.4 8.9 37.9 30.5 11.1 41.4 15.4 18.9 61.8 39.1 25.1 12.0 17.0 19.4 19.1 36.7 21.2 36.1 11.0 16.4 31.0 10.3 4.5 31.9 14.0 11.1 24.0 27.7 6.3 16.5 23.6 26.3 69.8 16.6 23.8 55.6 4.3 9.5 19.2 23.7 14.7 112.7 202.8 49.8 78.8 11.4 16.1 141.4 46.2 32.9 66.5 42.8 96.6 197.3 40.4 32.4 30.8 62.0 169.4 47.5 50.8 16.6 93.5 40.1 24.0 134.8 52.0 13.9 41.5 39.4 8.0 25.0 66.3 18.9 24.0 46.5 112.6 83.5 34.0 36.4 432.4 151.3 106.1 63.7 97.3 121.0 157.2 66.6 136.8 42.1 36.0 125.1 100.1 143.9 135.9 36.8 13.7 230.5 40.7 28.3 75.9 114.8 95.6 90.7 34.6 100.7 39.6 71.4 41.9 74.0 1.7 1.1 0.4 1.4 1.6 2.3 35.8 2.9 3.9 2.8 52.9 1.1 1.7 0.8 4.5 5.7 11.0 5.7 3.8 15.7 15.4 14.3 20.1 15.4 18.9 17.0 19.4 16.4 16.5 16.6 14.7 2.7 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 89.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 95.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 37.4 0.2 0.0 0.0 0.0 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 472.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 942.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.4;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 266.5;HaCaT: 95.5;SiHa: 156.9;SK-BR-3: 227.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" NA Yes 2800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" 43.2 24.0 25.6 4.9 30.0 1.3 64.7 27.2 33.9 31.7 21.8 42.5 57.9 23.7 28.5 54.7 23.2 24.5 47.1 25.5 25.9 73.8 472.8 86.7 8.1 31.0 29.0 17.5 53.6 29.7 19.5 109.9 29.8 79.5 51.6 7.8 66.6 22.1 18.5 123.1 69.3 13.4 27.8 8.6 40.7 4.1 27.6 21.0 79.9 38.6 12.5 36.9 55.5 35.2 15.1 5.9 0.9 11.5 2.1 0.1 266.5 0.0 0.5 0.2 0.3 13.9 32.0 0.0 26.3 0.0 9.0 95.5 6.6 35.3 0.2 9.8 2.2 0.1 19.0 76.1 0.9 0.2 1.5 4.9 84.5 0.0 30.2 7.3 53.6 0.9 2.8 0.3 0.0 52.2 0.3 1.1 1.7 52.3 17.7 6.1 1.5 9.3 66.4 22.4 9.8 14.2 156.9 227.1 6.0 48.8 51.1 0.0 6.7 0.1 9.1 0.6 1.5 2.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 1.0 0.7 0.0 0.3 11.4 5.9 0.4 0.4 0.0 0.0 0.0 1.6 25.6 30.0 27.2 33.9 25.5 25.9 31.0 29.0 29.8 27.8 27.6 35.2 116.8 198.7 113.1 0.7 2.3 127.7 103.7 91.6 327.8 3.0 198.3 151.9 47.8 95.8 101.2 18.4 0.0 195.6 4.4 265.0 13.7 130.1 0.3 100.4 19.1 148.9 18.6 4.0 0.7 63.9 942.6 23.2 124.9 163.5 6.3 0.1 106.4 133.2 28.2 5.0 0.8 114.1 101.7 4.3 19.5 0.7 4.7 4.2 62.2 2.8 0.6 5.7 0.0 3.5 28.7 73.9 205.5 0.4 4.1 197.8 238.6 34.5 54.5 1.1 0.0 6.5 35.9 0.8 2.6 253.2 217.8 254.2 7.5 1.3 95.9 135.9 EFNA4 "EPLG4, LERK4" ENSG00000243364 "Ephrin A4" P52798 1 155063737-155069553 "Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 30.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.1;Theca cells: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB021350 Uncertain "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB021350: " "unprognostic (4.65e-2)" "unprognostic (8.07e-2)" "unprognostic (3.43e-2)" "unprognostic (7.04e-2)" "unprognostic (7.91e-2)" "unprognostic (4.81e-1)" "prognostic unfavorable (1.00e-5)" "unprognostic (1.37e-2)" "unprognostic (3.89e-2)" "unprognostic (6.17e-2)" "unprognostic (2.87e-2)" "unprognostic (7.97e-3)" "prognostic unfavorable (3.14e-4)" "prognostic favorable (3.60e-5)" "unprognostic (3.35e-2)" "unprognostic (1.97e-1)" "unprognostic (6.29e-2)" 3.7 12.0 3.2 4.5 3.3 1.3 9.4 3.3 3.4 11.1 4.5 11.7 10.5 6.5 12.4 18.6 4.9 5.2 3.5 3.3 3.0 6.9 8.3 4.5 5.1 3.6 3.4 9.9 5.7 7.9 2.5 4.5 3.5 9.1 12.1 0.9 13.1 4.3 1.3 30.2 10.7 4.3 3.4 6.5 5.9 2.3 3.3 3.8 6.2 1.8 7.3 4.8 14.2 3.5 11.4 8.5 20.4 30.4 11.8 7.5 17.0 5.1 9.6 9.7 9.0 12.5 18.5 14.6 28.2 5.1 7.7 26.2 12.3 7.6 3.9 6.9 3.7 1.4 7.7 17.8 4.3 3.3 22.0 4.5 23.2 4.9 5.7 8.4 19.7 11.9 6.2 9.5 5.5 25.2 7.5 8.3 37.6 43.3 17.5 26.0 8.1 14.3 15.2 9.6 4.9 22.3 10.1 37.1 4.5 14.7 24.3 10.2 10.2 5.8 17.0 11.7 7.8 9.7 11.0 14.6 5.5 7.8 5.9 0.1 10.1 7.3 7.7 9.2 8.0 22.9 8.5 8.8 8.3 17.3 11.8 8.1 10.9 3.9 13.7 25.2 8.9 6.6 3.2 3.3 3.3 3.4 3.3 3.0 3.6 3.4 3.5 3.4 3.3 3.5 2.5 0.0 6.3 2.0 9.0 25.1 8.6 21.2 19.4 0.2 20.7 15.6 1.3 8.6 12.1 16.5 0.0 9.2 12.3 23.9 1.9 32.4 0.1 4.9 4.5 6.8 3.0 2.1 0.2 14.0 86.1 8.4 3.6 6.6 1.3 15.6 5.7 3.6 12.8 0.0 0.2 18.7 8.2 6.3 6.8 0.4 7.8 5.3 17.8 1.0 5.9 5.6 4.1 0.0 0.8 21.5 37.0 5.7 2.2 21.2 38.3 4.4 6.5 0.2 0.0 1.7 6.0 0.5 4.1 15.4 32.7 9.9 7.2 73.3 28.3 10.8 ERVH48-1 "C21orf105, NDUFV3-AS1, SUPYN" ENSG00000233056 "Endogenous retrovirus group 48 member 1" M5A8F1 21 42916803-42925646 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "placenta: 152.2" "Group enriched" "Detected in some" 8 "Cytotrophoblasts: 130.7;Extravillous trophoblasts: 258.3;Syncytiotrophoblasts: 88.8" "Cancer enriched" "Detected in some" 18 "testis cancer: 74.5" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 7 "BEWO: 296.4" "Secreted in female reproductive system" NA NA 57000 "Cluster 1: Neutrophils - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (5.28e-2)" "unprognostic (5.92e-2)" "unprognostic (5.66e-2)" "unprognostic (9.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.92e-2)" "unprognostic (3.48e-1)" "unprognostic (1.52e-2)" "unprognostic (7.74e-2)" "unprognostic (3.12e-3)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" 0.1 0.4 0.5 0.2 0.8 0.7 0.1 2.3 1.3 0.0 0.7 0.1 0.3 0.2 0.2 0.1 0.1 0.3 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.6 0.0 0.2 0.7 0.0 152.2 0.7 0.7 0.0 1.5 0.4 0.0 0.4 0.8 0.5 0.0 0.0 0.4 0.3 1.4 0.4 1.3 0.4 0.0 0.0 0.0 0.5 0.0 0.3 0.7 0.1 0.0 0.0 296.4 0.1 0.0 0.0 0.0 11.9 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 2.8 1.4 0.4 0.1 1.2 0.2 0.0 0.0 0.2 0.0 0.1 11.1 1.0 0.7 0.6 0.0 0.2 8.2 5.0 0.9 0.0 0.3 6.4 0.3 0.1 0.0 0.2 0.4 0.3 0.1 0.0 0.0 44.6 0.3 0.2 0.3 0.2 0.6 0.4 0.1 0.9 2.9 0.5 0.4 3.0 0.2 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.6 7.7 0.0 0.0 0.0 0.0 0.0 0.5 0.8 2.3 1.3 0.6 0.0 0.6 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 130.7 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.4 0.0 0.0 0.0 0.0 258.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 19.2 3.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 88.8 0.0 0.0 0.0 0.0 ERVMER34-1 envMER34 ENSG00000226887 "Endogenous retrovirus group MER34 member 1, envelope" Q9H9K5 4 52722618-52751586 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 12.9;placenta: 10.8" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 74.4;Extravillous trophoblasts: 102.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 46.9;hTCEpi: 32.5;RPTEC TERT1: 24.2" "HPA011423, HPA024053" Approved Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 6000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA011423: AB_2668510, HPA024053: " "unprognostic (5.34e-2)" "unprognostic (1.29e-1)" "unprognostic (1.91e-3)" "unprognostic (5.86e-2)" "unprognostic (4.08e-4)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.88e-4)" "unprognostic (5.28e-2)" "unprognostic (2.99e-2)" "unprognostic (2.39e-3)" "unprognostic (2.62e-3)" "unprognostic (4.23e-2)" "unprognostic (1.03e-2)" "unprognostic (1.32e-2)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" "unprognostic (1.82e-1)" 0.1 0.5 1.0 0.2 0.7 0.0 0.9 0.7 1.2 0.8 0.7 0.2 0.2 0.6 0.6 1.2 0.5 0.2 2.6 0.8 0.8 3.5 0.1 0.6 0.2 0.9 0.7 1.3 0.5 12.9 0.0 10.8 1.0 0.4 0.4 0.0 0.4 0.8 0.0 0.3 0.1 0.2 0.9 0.5 0.4 0.7 0.8 0.0 0.4 0.0 0.4 0.5 0.6 1.0 7.6 0.3 1.5 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 46.9 9.9 0.0 1.0 0.1 0.7 0.5 0.0 3.4 0.0 0.0 0.4 0.0 0.1 0.5 0.6 0.0 0.0 2.1 32.5 0.0 4.8 0.0 0.0 0.0 2.7 0.0 0.1 0.5 0.0 0.0 3.1 3.0 1.4 0.0 0.0 0.0 24.2 0.7 2.0 0.4 3.1 1.3 0.0 4.7 4.1 0.7 0.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.7 1.2 0.8 0.8 0.9 0.7 1.0 0.9 0.8 1.0 0.1 0.0 0.0 0.0 0.5 0.5 1.8 2.3 2.2 0.0 2.2 1.9 2.9 0.0 0.6 7.3 0.0 74.4 0.0 0.1 0.0 2.5 4.2 0.6 0.9 1.3 0.0 0.0 0.4 0.8 102.9 1.5 0.0 1.7 0.0 2.6 0.0 0.0 7.4 0.0 0.2 0.3 2.0 0.0 0.0 3.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.0 0.0 3.7 0.0 3.0 0.1 0.0 0.0 0.2 0.5 0.2 0.4 2.8 0.1 17.4 0.0 0.2 0.4 1.4 ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 23.3;Cholangiocytes: 17.2;Distal tubular cells: 17.6;Enteroendocrine cells: 14.9;Extravillous trophoblasts: 19.8;Syncytiotrophoblasts: 14.9" "Cancer enhanced" "Detected in all" "testis cancer: 80.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 177.7;Hep G2: 173.0;SK-MEL-30: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA005768: AB_1848294" "unprognostic (2.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.58e-2)" "unprognostic (5.34e-2)" "unprognostic (8.13e-2)" "unprognostic (7.05e-2)" "unprognostic (3.01e-1)" "unprognostic (7.79e-2)" "unprognostic (2.03e-1)" "unprognostic (7.08e-2)" "prognostic favorable (7.60e-4)" "unprognostic (1.69e-1)" 0.5 2.4 1.2 1.0 1.6 0.0 7.0 0.8 2.2 3.6 0.0 2.0 6.1 2.4 1.0 9.2 2.5 6.4 3.1 1.3 0.8 5.4 1.2 2.2 0.6 1.0 0.9 0.4 7.8 7.9 14.7 5.2 1.4 4.5 1.7 3.0 4.6 3.6 1.3 6.4 4.2 1.4 0.3 0.4 3.8 1.2 0.7 0.3 6.9 2.5 4.8 2.1 5.3 0.9 24.5 67.0 80.4 177.7 3.1 20.1 17.9 7.9 21.1 14.9 15.2 38.1 33.9 0.1 4.3 4.1 36.6 43.6 2.7 40.2 13.2 0.8 0.5 2.3 10.7 173.0 4.3 47.0 20.9 3.6 1.4 56.8 35.0 16.8 32.1 0.3 48.9 0.1 31.0 9.8 0.2 82.9 116.9 123.1 110.9 99.8 9.8 58.9 33.0 17.3 0.1 71.4 2.1 4.5 197.0 43.8 0.8 13.9 15.1 10.6 52.0 15.7 22.1 7.3 47.8 0.1 18.9 8.9 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.8 2.2 1.3 0.8 1.0 0.9 1.4 0.3 0.7 0.9 0.2 0.0 0.0 1.3 0.0 1.9 2.5 3.6 23.3 3.2 10.4 12.3 1.1 17.2 2.4 0.0 0.0 2.3 0.1 1.1 17.6 6.5 3.1 0.7 0.3 1.5 14.9 0.0 1.6 1.0 19.8 1.9 3.1 1.6 0.0 0.2 0.7 0.0 0.8 0.0 1.0 4.0 2.0 0.3 0.3 6.0 0.3 0.2 3.6 1.0 0.0 10.9 0.0 1.0 0.0 3.7 3.3 0.4 0.0 0.9 1.9 0.1 1.0 0.3 0.0 2.1 1.7 0.0 1.3 3.6 1.1 14.9 0.3 0.1 7.7 4.3 EXOSC5 "hRrp46p, MGC12901, p12B, RRP41B, RRP46, Rrp46p" ENSG00000077348 "Exosome component 5" Q9NQT4 19 41386374-41397359 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053150, HPA055677" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA053150: AB_2682058, HPA055677: AB_2682882" "unprognostic (1.24e-1)" "unprognostic (5.68e-2)" "unprognostic (2.99e-1)" "unprognostic (2.53e-3)" "unprognostic (7.50e-3)" "unprognostic (5.74e-2)" "unprognostic (3.83e-3)" "unprognostic (9.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.54e-1)" "unprognostic (9.39e-2)" "unprognostic (2.35e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (6.84e-2)" "unprognostic (2.27e-1)" "unprognostic (7.79e-2)" "unprognostic (7.82e-2)" 12.9 19.4 18.6 14.1 20.2 17.4 14.0 18.9 26.1 12.5 15.1 13.3 11.4 11.3 4.2 21.4 15.1 6.6 16.8 18.8 17.8 9.9 21.7 7.3 22.0 20.8 18.4 14.3 28.6 5.9 7.2 7.4 19.2 11.0 7.2 2.3 16.4 8.4 41.7 23.0 10.8 7.2 19.0 14.3 13.6 11.4 18.3 14.8 11.6 23.1 11.8 14.7 13.9 22.1 58.2 123.5 15.1 48.8 10.7 13.5 39.4 24.5 13.1 44.6 37.0 72.5 47.5 92.9 64.8 12.9 22.8 25.1 33.1 31.3 12.2 66.7 117.3 42.7 45.5 55.7 32.1 76.7 41.8 16.3 69.0 35.6 33.8 12.1 21.1 57.7 57.5 70.2 14.2 88.1 70.2 58.6 56.6 85.2 59.9 66.9 40.9 94.8 17.6 43.1 64.4 47.8 34.6 62.4 68.2 10.5 31.1 95.6 16.2 45.9 37.4 30.1 76.9 109.6 138.5 106.3 34.9 116.0 39.0 15.2 68.2 1.9 41.3 77.7 47.9 66.0 43.3 40.9 110.1 74.0 63.2 55.4 5.0 62.1 48.6 118.7 37.0 48.6 18.6 20.2 18.9 26.1 18.8 17.8 20.8 18.4 19.2 19.0 18.3 22.1 16.1 3.2 4.8 2.3 21.3 30.5 29.0 29.6 44.9 5.5 30.1 44.2 8.4 22.8 16.9 18.4 4.2 28.4 23.5 12.7 37.2 21.7 9.1 5.5 16.7 11.1 8.5 28.0 5.0 21.4 124.0 13.1 16.3 9.1 5.1 24.7 7.1 20.3 28.8 6.7 4.8 18.4 20.3 11.8 13.3 8.5 16.8 18.9 14.2 2.8 18.9 7.0 18.6 4.0 4.3 17.2 15.3 12.4 21.3 28.0 6.6 34.9 12.7 4.1 6.6 17.8 16.0 17.0 33.1 47.4 33.2 21.2 17.0 31.5 34.2 23.8 EZHIP "CATACOMB, CXorf67" ENSG00000187690 "EZH inhibitory protein" Q86X51 X 51406948-51408843 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 5.9" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 2.3;Extravillous trophoblasts: 2.5;Syncytiotrophoblasts: 1.9" "Cancer enriched" "Detected in some" 6 "testis cancer: 11.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 45 "U-2 OS: 32.8" "HPA004003, HPA006128" Enhanced Enhanced Nucleoplasm NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA004003: AB_2667113, HPA006128: AB_2667517" "unprognostic (4.21e-2)" "unprognostic (6.36e-2)" "unprognostic (3.37e-2)" "unprognostic (8.58e-3)" "unprognostic (3.57e-4)" "unprognostic (1.47e-6)" "unprognostic (4.55e-2)" "unprognostic (3.06e-2)" "unprognostic (4.26e-1)" 0.0 0.2 0.7 0.0 0.7 0.0 0.0 0.6 0.6 0.2 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.2 1.4 0.2 0.0 0.1 0.0 0.5 0.3 0.4 0.1 0.0 1.0 0.9 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 5.9 0.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.6 0.6 0.2 1.4 0.5 0.3 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 FAM89A "C1orf153, MGC15887" ENSG00000182118 "Family with sequence similarity 89 member A" Q96GI7 1 231018958-231040254 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.0;placenta: 68.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 186.3;Extravillous trophoblasts: 267.5;Rod photoreceptor cells: 102.5;Syncytiotrophoblasts: 278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 145.4;SK-MEL-30: 81.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059052, HPA059578" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles" Nucleoplasm "HPA059052: AB_2683890, HPA059578: AB_2684070" "unprognostic (7.80e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-3)" "unprognostic (1.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.10e-1)" "unprognostic (8.05e-3)" "unprognostic (4.85e-1)" "unprognostic (1.54e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.87e-2)" "unprognostic (2.03e-1)" "unprognostic (2.01e-1)" "unprognostic (9.26e-2)" 60.0 18.0 16.0 4.8 15.3 5.9 36.5 20.7 16.4 11.0 21.3 4.4 1.7 7.5 1.6 6.5 7.1 5.9 10.6 14.2 23.4 22.2 9.2 19.2 5.9 22.6 21.4 6.0 10.6 6.0 5.8 68.2 20.9 7.1 2.7 17.3 5.3 4.6 5.9 30.6 4.6 4.1 21.2 17.5 7.6 3.0 25.1 2.9 5.5 6.7 4.7 8.9 9.2 19.5 0.9 13.7 6.3 13.4 15.0 3.0 145.4 7.8 5.8 2.8 5.1 21.1 12.1 0.0 1.8 5.1 16.7 8.4 12.0 1.9 2.3 42.4 28.9 6.7 0.3 0.9 57.6 5.0 35.2 50.1 26.6 0.0 13.2 0.1 7.4 15.0 53.4 8.6 2.7 5.0 3.2 8.8 9.4 12.6 4.3 16.6 20.3 16.0 10.1 14.8 5.8 16.1 2.6 1.2 81.6 13.9 0.8 29.2 1.1 22.5 0.1 0.4 14.7 18.3 23.7 11.6 6.7 9.8 45.7 1.4 0.2 0.0 0.2 0.0 0.3 0.3 0.2 0.5 0.0 0.1 0.4 0.9 0.0 0.1 0.0 0.0 0.0 0.2 16.0 15.3 20.7 16.4 14.2 23.4 22.6 21.4 20.9 21.2 25.1 19.5 82.3 0.0 2.6 3.6 4.2 30.1 22.0 0.3 8.0 48.1 3.8 5.2 3.3 7.2 0.7 0.0 77.2 186.3 4.9 0.3 3.9 2.8 1.3 1.3 39.3 44.5 0.0 14.9 1.1 3.3 267.5 11.6 0.5 2.6 4.5 0.5 10.8 11.1 51.0 8.4 10.8 0.6 0.0 19.6 2.1 3.6 2.8 8.5 21.4 22.5 0.5 26.2 1.0 10.1 2.0 4.4 0.5 1.5 1.4 30.2 0.0 5.1 0.1 102.5 0.0 9.9 8.5 4.2 11.6 1.7 32.8 278.3 5.5 0.4 1.3 15.4 FANCE "FACE, FAE" ENSG00000112039 "FA complementation group E" Q9HB96 6 35452338-35467102 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 22.1;Extravillous trophoblasts: 104.8;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB014893 Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB014893: " "unprognostic (2.66e-1)" "unprognostic (8.01e-3)" "unprognostic (7.73e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.80e-3)" "prognostic unfavorable (2.08e-9)" "unprognostic (8.90e-2)" "unprognostic (5.70e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.14e-2)" 4.6 1.5 2.6 3.2 2.5 5.8 5.0 2.8 3.1 7.1 2.0 3.1 2.1 3.7 3.4 8.6 4.8 1.5 3.3 2.3 2.9 2.1 1.3 4.1 4.5 2.7 2.6 7.8 3.5 4.0 3.1 9.3 2.6 3.8 3.0 1.8 4.3 2.7 11.0 13.8 3.5 3.1 2.4 3.8 3.4 8.7 2.7 2.6 3.0 3.1 5.7 4.0 7.7 2.7 9.9 4.2 12.8 27.6 9.2 15.9 34.6 11.4 9.6 14.8 12.1 11.1 5.3 33.0 7.5 6.7 11.2 7.2 13.7 9.8 13.9 11.0 11.9 23.8 11.7 6.8 4.8 12.6 8.2 10.1 28.6 17.7 27.7 3.9 8.7 12.6 21.3 11.6 12.2 11.4 5.8 16.6 4.7 10.6 7.0 18.8 12.3 12.1 3.1 10.0 12.1 11.4 6.4 9.1 10.0 11.9 8.8 43.7 5.6 16.7 14.5 10.9 18.1 7.4 29.3 11.6 3.9 24.3 16.8 0.0 0.2 0.2 0.4 0.1 0.7 0.1 0.6 0.9 0.1 0.5 0.3 0.3 0.0 0.5 0.1 0.4 0.3 0.2 2.6 2.5 2.8 3.1 2.3 2.9 2.7 2.6 2.6 2.4 2.7 2.7 7.0 6.4 0.0 1.0 2.4 8.8 4.1 4.7 1.8 1.1 2.0 2.8 2.7 0.0 1.6 0.0 0.0 22.1 2.0 1.6 0.0 1.7 0.3 1.9 2.4 3.7 1.2 2.5 0.4 0.8 104.8 2.8 1.1 3.4 0.0 5.2 1.4 0.7 6.0 0.0 0.9 3.6 0.0 0.8 1.3 0.6 1.5 1.4 1.8 2.8 0.5 1.9 1.0 0.5 1.0 1.1 0.4 0.7 3.1 5.8 1.1 0.3 0.1 2.0 0.0 4.0 3.4 8.2 13.2 4.6 7.1 46.7 2.2 3.4 4.4 3.5 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 3647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 164.7;hTCEpi: 181.2;SiHa: 341.5;U-2197: 173.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" 82.9 163.3 16.6 24.1 15.3 13.3 62.4 13.3 19.8 75.6 16.0 82.7 7.7 62.0 6.1 22.0 70.2 16.5 124.1 16.4 17.3 55.9 26.2 132.7 5.5 22.6 16.0 63.8 49.3 3.2 28.9 179.4 17.9 74.9 5.9 2.4 21.1 22.1 11.7 32.3 36.5 42.4 16.7 22.6 43.2 75.2 18.1 2.3 37.9 4.9 1.6 70.5 63.1 18.9 9.5 74.0 5.1 3.7 22.3 56.4 164.7 126.1 18.5 30.7 11.3 27.1 14.4 4.1 49.4 84.7 17.6 65.2 4.1 106.4 10.1 7.8 8.7 3.5 110.2 22.4 95.6 6.7 12.0 70.7 181.2 34.0 140.2 79.3 5.5 3.9 8.2 5.3 46.7 33.1 2.4 4.0 6.2 62.0 26.2 7.2 3.4 8.7 43.1 1.7 3.3 5.7 341.5 6.9 4.3 6.4 6.2 3.5 75.5 30.6 106.6 173.4 46.9 8.5 4.4 2.3 4.7 20.0 14.2 0.0 1.9 0.0 0.4 1.8 0.0 0.1 0.6 0.4 0.9 0.3 1.0 0.6 0.0 0.2 1.4 0.3 0.0 0.9 16.6 15.3 13.3 19.8 16.4 17.3 22.6 16.0 17.9 16.7 18.1 18.9 4.6 19.2 1.9 40.5 1.5 14.5 31.0 11.7 1.8 1.3 11.3 7.9 16.7 32.9 4.4 9.2 0.0 53.9 1.0 1.1 7.9 86.1 8.8 6.4 14.8 8.7 1.2 1.7 9.8 64.3 3647.6 59.6 2.0 18.3 0.0 5.7 16.4 1.9 77.1 3.3 8.4 1.0 0.0 3.7 4.8 7.6 61.2 7.4 5.4 2.8 10.6 6.6 1.0 6.0 5.5 306.5 0.2 26.7 1.0 78.0 1.2 17.7 3.1 1.1 46.0 22.4 57.0 4.6 5.6 4.3 7.7 792.0 2.0 3.6 2.5 30.7 GCM1 "GCMA, hGCMa" ENSG00000137270 "Glial cells missing transcription factor 1" Q9NP62 6 53126961-53148841 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 20.2" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 230.3;Syncytiotrophoblasts: 266.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "BEWO: 39.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011343, HPA073469" Enhanced Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011343: AB_2668489, HPA073469: " "unprognostic (2.81e-2)" "unprognostic (4.09e-2)" "unprognostic (1.89e-2)" "unprognostic (1.53e-1)" "unprognostic (3.17e-1)" "unprognostic (7.68e-2)" "unprognostic (8.47e-3)" "unprognostic (2.83e-2)" "unprognostic (2.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.42e-1)" "unprognostic (5.98e-2)" "unprognostic (1.29e-4)" "unprognostic (1.86e-1)" "unprognostic (7.42e-2)" "unprognostic (2.96e-2)" 0.1 0.1 0.4 0.1 0.2 0.4 0.1 0.3 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 0.1 1.3 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 20.2 0.2 0.0 0.0 0.4 0.1 0.0 3.6 0.1 0.1 0.0 0.0 0.4 0.1 0.6 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.1 0.2 0.2 0.0 0.0 39.2 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.0 8.2 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.7 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.3 2.0 0.4 0.0 0.4 0.0 0.0 0.1 0.2 230.3 0.5 0.0 0.6 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 11.7 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 266.1 0.1 0.0 0.0 0.1 GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 553.4;Extravillous trophoblasts: 1476.4;Proximal tubular cells: 655.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" 28.7 20.1 58.9 6.9 66.5 6.3 24.2 62.9 113.8 18.2 50.8 16.0 7.2 17.5 68.9 15.5 19.8 11.7 38.1 55.8 60.9 78.2 118.9 10.8 6.7 60.1 66.0 18.4 19.7 31.0 14.3 26.0 61.1 18.7 13.0 15.6 15.6 16.7 59.3 10.1 9.5 11.8 61.7 6.3 17.5 7.4 63.7 10.4 96.4 63.6 9.3 18.3 15.2 67.8 63.6 28.3 82.4 37.0 40.4 30.9 175.5 35.9 26.4 43.3 20.6 37.0 57.2 17.2 32.3 15.9 31.9 33.3 64.5 36.5 71.6 4.7 86.7 21.8 34.9 114.6 45.7 70.3 24.1 32.0 47.8 26.8 53.7 13.0 22.3 45.1 86.3 3.4 42.9 67.7 45.9 138.8 113.0 49.6 57.5 72.7 44.1 25.5 98.4 56.4 43.7 45.3 53.3 32.9 70.8 63.9 48.3 33.2 19.8 27.6 49.3 44.0 37.8 14.7 31.8 102.1 18.2 41.3 22.6 3.6 1.3 1.3 2.8 2.1 4.6 3.5 2.6 4.0 3.9 2.5 4.4 5.9 1.7 7.0 1.7 10.8 2.2 2.4 58.9 66.5 62.9 113.8 55.8 60.9 60.1 66.0 61.1 61.7 63.7 67.8 31.1 3.2 5.9 16.3 24.8 29.1 94.6 73.6 52.3 43.7 97.9 115.6 12.9 44.3 31.4 80.9 37.5 553.4 13.8 15.3 295.4 70.0 32.4 34.8 128.3 31.9 26.4 71.1 12.6 42.5 1476.4 61.6 31.1 55.2 36.3 38.5 33.2 352.0 118.8 38.7 11.9 34.3 67.1 19.7 34.6 19.5 140.8 18.8 85.4 4.7 17.7 215.8 19.6 19.6 35.2 42.3 17.8 141.1 51.7 123.9 13.7 655.9 20.0 45.7 32.9 46.2 50.2 20.7 77.3 78.4 27.1 228.8 16.3 114.5 49.4 69.8 GJA5 CX40 ENSG00000265107 "Gap junction protein alpha 5" P36382 1 147756199-147773362 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 36.7;placenta: 85.4" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 135.3;Extravillous trophoblasts: 345.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SK-BR-3: 133.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB013080, HPA071370" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB013080: AB_2533263, HPA071370: " "unprognostic (1.25e-1)" "unprognostic (6.34e-2)" "unprognostic (1.22e-2)" "unprognostic (2.94e-2)" "unprognostic (3.88e-2)" "unprognostic (8.95e-2)" "unprognostic (1.23e-3)" "unprognostic (5.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-1)" "unprognostic (4.27e-2)" "unprognostic (7.57e-2)" "unprognostic (1.97e-2)" "unprognostic (2.44e-1)" "unprognostic (4.41e-2)" "unprognostic (3.43e-2)" "unprognostic (8.93e-2)" 18.6 2.2 2.5 6.0 3.4 0.0 10.5 2.4 4.1 5.5 2.6 4.7 3.4 10.8 2.3 4.8 8.2 6.3 36.7 2.4 2.2 17.1 1.2 26.4 1.7 2.8 2.6 4.0 2.6 3.4 0.5 85.4 2.5 4.0 4.1 0.2 1.6 9.4 2.1 1.4 5.9 8.2 2.6 3.9 3.0 2.9 2.7 0.6 5.3 8.9 2.3 7.4 3.8 2.7 1.8 0.0 0.3 0.0 0.0 0.0 5.7 4.4 2.2 2.2 0.5 0.1 0.2 0.0 1.4 0.7 0.0 0.3 0.0 9.3 3.5 0.0 0.3 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.1 13.1 0.0 0.1 0.1 0.2 133.8 0.0 12.2 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.4 2.4 4.1 2.4 2.2 2.8 2.6 2.5 2.6 2.7 2.7 14.3 3.2 4.2 0.0 1.0 0.0 0.0 0.0 0.6 0.0 0.2 1.5 17.7 0.0 0.0 3.7 0.0 135.3 0.1 0.0 0.0 0.0 7.6 0.1 0.3 14.7 0.0 0.0 0.0 0.0 345.3 3.7 0.0 0.1 0.0 19.9 37.9 0.0 15.8 0.0 0.0 0.0 0.0 0.6 0.0 9.8 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 39.5 0.5 11.1 4.3 0.4 0.2 0.3 31.1 0.5 0.1 0.0 0.1 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703145 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 2571.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 1500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: AB_2684126" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 55.4 62.3 69.4 38.9 74.1 31.6 74.2 74.6 83.4 55.9 77.2 51.8 116.3 57.8 110.9 60.0 72.3 41.4 88.9 72.6 76.2 87.2 157.7 66.6 48.4 73.7 72.8 82.8 42.1 106.1 23.2 64.1 75.1 171.4 52.3 100.3 43.2 62.1 154.2 66.6 67.7 61.8 77.9 48.2 48.5 27.9 72.9 50.0 54.8 128.8 60.3 52.4 51.6 77.1 201.6 92.0 257.4 256.7 119.2 213.9 227.0 171.1 161.4 235.4 243.0 224.4 75.3 222.5 132.2 137.5 280.1 129.5 222.5 221.1 295.8 203.8 343.0 329.4 105.7 211.3 178.5 126.7 2571.5 183.9 133.5 223.7 159.0 153.2 258.5 154.9 264.7 143.6 223.3 170.6 199.5 160.5 185.5 179.2 176.7 171.0 311.1 145.8 217.8 149.9 199.3 201.3 120.6 165.4 329.8 175.9 192.4 628.3 107.6 182.0 167.1 159.8 275.9 112.7 227.0 608.6 66.1 322.7 299.6 23.7 20.7 15.3 35.5 33.4 48.0 51.9 35.3 36.7 39.0 51.4 32.7 34.9 2.7 23.5 26.9 60.4 34.1 33.3 69.4 74.1 74.6 83.4 72.6 76.2 73.7 72.8 75.1 77.9 72.9 77.1 69.2 131.4 174.4 26.1 86.3 64.6 112.6 88.2 37.0 56.1 67.7 55.8 133.2 58.6 84.5 90.1 20.9 102.7 68.3 34.1 248.4 132.1 4.5 76.2 58.8 74.3 36.5 83.5 23.9 73.3 323.0 86.0 53.0 67.5 71.4 78.7 161.0 114.0 78.8 69.0 21.9 39.3 99.7 125.7 72.8 6.5 83.9 70.0 104.9 17.8 92.6 190.3 49.4 25.1 24.8 77.3 36.0 109.9 86.4 178.8 103.2 132.2 80.7 65.5 46.0 62.0 70.9 15.0 16.1 77.2 88.2 73.2 62.4 123.7 63.4 130.2 GM2A SAP-3 ENSG00000196743 "GM2 ganglioside activator" P17900 5 151212150-151270440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Gangliosidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.7;Hofbauer cells: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 30.9;dendritic cells: 39.6;monocytes: 40.4" "Cell line enhanced" "Detected in all" "BEWO: 207.1;HBEC3-KT: 291.8;hTCEpi: 287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008063 Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" "HPA008063: AB_1849842" "unprognostic (4.33e-2)" "unprognostic (8.97e-3)" "unprognostic (2.27e-1)" "unprognostic (3.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.77e-5)" "unprognostic (1.22e-1)" "unprognostic (1.72e-2)" "unprognostic (1.31e-2)" "unprognostic (1.50e-2)" "unprognostic (5.33e-3)" "unprognostic (9.81e-2)" "unprognostic (4.24e-2)" "unprognostic (4.42e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" 17.4 20.5 29.3 30.0 39.7 20.6 28.0 38.9 31.1 30.8 17.9 19.7 15.8 15.1 30.8 56.2 15.4 23.4 26.2 27.1 34.3 11.4 24.8 39.0 61.4 42.6 37.9 21.3 14.9 28.3 6.6 57.9 44.3 21.1 26.3 11.7 17.0 17.9 7.2 81.8 16.3 20.0 39.0 36.0 15.8 11.6 36.2 72.3 13.0 10.5 77.9 40.3 49.5 46.7 22.3 14.8 15.1 71.7 98.0 48.2 207.1 35.0 75.1 19.0 25.6 30.3 26.1 71.9 35.1 26.9 51.1 60.0 16.7 291.8 27.2 41.4 10.5 11.7 16.8 37.9 23.7 19.1 117.1 65.4 287.0 24.4 16.4 26.0 27.6 85.1 11.4 30.7 30.1 9.6 38.4 18.0 10.2 11.4 32.3 17.7 7.1 46.3 18.4 43.3 3.9 13.4 29.1 133.0 58.3 52.0 30.7 22.5 24.6 46.0 17.6 38.3 10.6 75.2 96.8 187.0 53.1 30.1 19.4 7.6 40.4 2.4 3.7 13.6 2.7 30.9 4.3 3.9 39.6 29.8 6.1 4.8 8.7 4.4 3.4 28.0 5.4 18.6 29.3 39.7 38.9 31.1 27.1 34.3 42.6 37.9 44.3 39.0 36.2 46.7 5.8 16.0 23.0 5.5 25.0 14.9 18.5 63.2 26.7 5.8 5.4 15.5 30.9 0.0 29.7 18.4 2.1 53.6 8.3 4.4 1.9 7.2 0.5 5.7 6.8 7.3 3.6 5.0 2.2 8.1 224.7 10.2 10.7 7.7 69.6 16.3 8.6 24.2 100.8 6.7 2.7 5.4 10.2 55.7 32.5 1.6 8.1 67.8 8.8 2.8 52.5 8.0 7.2 3.5 9.5 6.0 4.7 13.9 28.8 6.7 6.2 5.4 19.9 3.7 0.0 7.9 6.9 1.8 4.2 45.6 23.9 52.5 5.6 6.4 6.7 36.5 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 GPR146 PGR8 ENSG00000164849 "G protein-coupled receptor 146" Q96CH1 7 1044546-1059261 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "adipose tissue: 47.9" "Cell type enhanced" "Detected in many" "Adipocytes: 96.3;Endothelial cells: 45.3;Extravillous trophoblasts: 243.2;Syncytiotrophoblasts: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 95.2;naive CD4 T-cell: 25.6" "Group enriched" "Detected in many" 4 "granulocytes: 95.2;T-cells: 25.6" "Cell line enhanced" "Detected in many" "BEWO: 23.0;NB-4: 7.1" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.39e-2)" "unprognostic (7.83e-2)" "unprognostic (6.27e-4)" "unprognostic (5.51e-3)" "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (2.69e-1)" "unprognostic (2.99e-2)" "unprognostic (3.48e-3)" "unprognostic (2.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (3.27e-3)" "unprognostic (1.41e-1)" "unprognostic (4.19e-2)" "unprognostic (1.03e-2)" 47.9 2.6 16.9 2.0 17.2 9.0 41.8 17.0 20.9 10.0 22.1 14.1 2.8 13.2 2.8 4.7 12.3 7.5 13.2 13.6 15.4 5.3 20.4 24.9 4.1 18.6 18.4 7.4 5.9 1.6 3.4 10.2 18.7 7.2 1.0 3.6 9.6 5.5 10.7 11.2 8.1 3.5 16.6 6.7 12.9 2.6 21.8 1.7 11.5 8.8 1.2 13.2 8.7 17.3 1.2 1.0 0.4 1.0 1.3 0.3 23.0 0.1 0.9 0.2 1.1 0.8 1.1 0.4 0.7 0.1 3.5 0.8 0.0 0.3 0.1 0.8 0.9 1.7 0.7 1.9 1.5 0.1 0.2 0.5 0.0 0.7 0.0 2.4 1.7 0.6 1.1 1.2 0.2 0.7 0.0 7.1 1.6 1.3 0.6 5.5 0.0 1.5 0.3 0.1 1.2 1.7 1.8 0.2 2.0 0.9 1.1 2.2 0.5 1.0 1.1 1.6 0.8 1.9 2.1 0.1 6.1 2.2 2.1 0.0 0.2 95.2 0.6 0.1 1.2 0.0 8.4 0.7 1.7 0.1 25.6 4.8 0.1 1.3 0.3 14.3 14.5 4.3 16.9 17.2 17.0 20.9 13.6 15.4 18.6 18.4 18.7 16.6 21.8 17.3 96.3 0.0 2.8 7.2 3.3 1.8 0.8 1.8 1.2 3.7 7.6 3.4 0.3 1.5 2.1 1.8 0.0 9.3 1.4 0.3 1.9 1.0 0.1 3.2 0.4 45.3 4.2 30.5 0.9 0.6 243.2 4.8 2.0 3.7 2.5 1.7 16.4 21.3 10.9 3.3 1.4 0.3 2.0 0.6 6.1 1.1 3.1 1.7 3.6 3.7 0.2 21.2 2.1 4.5 1.7 0.7 0.3 3.4 0.9 0.7 0.8 3.4 0.0 5.7 0.0 2.3 1.4 0.5 1.5 0.4 2.3 82.4 2.5 0.9 1.0 0.4 GPR32 RVDR1 ENSG00000142511 "G protein-coupled receptor 32" O75388 19 50770464-50771732 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 32 "parathyroid gland: 58.0" "Group enriched" "Detected in some" 12 "Extravillous trophoblasts: 6.3;Syncytiotrophoblasts: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "BEWO: 37.4" "Not detected" "Not detected" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (4.77e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 GPR78 ENSG00000155269 "G protein-coupled receptor 78" Q96P69 4 8558725-8619761 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 1.4;placenta: 3.0" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 5.2" "Cancer enhanced" "Detected in single" "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "BEWO: 25.8" HPA013209 Uncertain NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA013209: AB_10601657" "unprognostic (6.41e-2)" "unprognostic (1.77e-2)" "unprognostic (1.17e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-2)" "unprognostic (3.70e-2)" "unprognostic (3.82e-4)" "unprognostic (6.46e-3)" "unprognostic (1.20e-1)" "unprognostic (3.80e-2)" "unprognostic (2.29e-1)" "unprognostic (4.88e-15)" "unprognostic (5.55e-3)" "unprognostic (3.93e-2)" "unprognostic (9.90e-3)" "unprognostic (8.15e-2)" 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 4.9 0.0 0.0 0.0 0.0 0.0 25.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 5.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 H2BC9 "H2B/j, H2BFJ, HIST1H2BH" ENSG00000275713 "H2B clustered histone 9" Q93079 6 26251651-26253710 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.2;vagina: 4.3" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.7;neutrophil: 3.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.7" "Cell line enhanced" "Detected in many" "U-266/70: 16.9" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (5.83e-2)" "unprognostic (6.27e-3)" "unprognostic (4.50e-2)" "unprognostic (9.18e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.06e-3)" "unprognostic (3.08e-3)" "unprognostic (1.58e-2)" "unprognostic (2.75e-2)" "unprognostic (1.86e-1)" "unprognostic (3.22e-1)" "unprognostic (2.96e-8)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (1.95e-3)" 0.5 0.2 0.4 0.6 0.4 1.4 0.6 0.3 0.5 1.9 0.8 2.0 3.0 0.4 0.8 4.2 0.8 0.3 0.2 0.3 0.4 0.9 0.2 1.6 0.8 0.8 0.7 0.1 0.0 0.1 0.1 0.2 0.7 3.5 0.8 0.0 1.3 0.0 0.0 0.6 1.7 0.1 0.6 3.7 0.7 0.6 0.7 2.9 1.0 0.1 0.5 0.4 4.3 1.1 1.8 0.1 7.0 0.0 0.0 0.1 1.1 0.9 0.3 1.2 0.6 2.4 1.1 0.0 1.7 0.1 1.8 3.4 0.0 0.6 1.7 0.9 0.1 1.3 6.1 0.4 0.0 0.0 4.0 0.3 0.3 0.4 0.5 0.0 0.3 1.0 2.7 6.2 0.1 2.0 3.8 2.7 1.6 0.0 1.8 4.0 0.0 0.9 0.0 2.7 3.2 2.9 4.2 1.4 0.6 0.3 2.0 3.3 0.0 0.6 0.0 0.7 3.1 16.9 4.5 0.0 0.5 1.5 3.8 3.7 0.2 0.6 0.3 0.0 0.1 0.6 0.2 0.4 0.6 0.3 0.0 0.1 3.0 0.8 0.1 0.2 0.4 5.2 0.4 0.4 0.3 0.5 0.3 0.4 0.8 0.7 0.7 0.6 0.7 1.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 29.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 966.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 50.9" "Lineage enriched" "Detected in all" 5 "T-cells: 50.9" "Cell line enhanced" "Detected in many" "HDLM-2: 34.7;U-2 OS: 31.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 9: U-2 OS - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA039237: AB_10805357" "unprognostic (1.67e-2)" "unprognostic (1.04e-3)" "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (3.27e-1)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (3.82e-1)" "unprognostic (3.37e-3)" "unprognostic (7.37e-3)" "unprognostic (1.13e-3)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.18e-13)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.12e-1)" 10.3 1.9 2.1 11.5 2.0 3.1 8.6 1.9 2.7 5.1 2.1 3.2 0.6 4.3 0.1 6.1 6.2 2.7 4.6 2.1 2.0 6.1 0.9 9.7 11.7 2.4 2.1 2.7 1.4 0.5 2.2 1.4 2.5 5.7 0.4 4.2 6.0 0.7 3.6 6.2 4.6 2.7 2.3 5.7 3.5 1.0 2.4 2.9 4.6 0.6 3.2 6.9 5.6 2.1 2.0 7.0 1.3 15.4 4.4 4.2 4.7 4.4 1.0 1.6 2.0 4.4 6.4 0.0 11.9 5.4 2.5 1.7 14.7 1.9 0.0 34.7 12.9 4.9 0.3 0.0 0.6 0.0 0.1 1.6 0.8 3.0 0.2 0.2 7.1 0.6 0.1 9.3 0.8 0.2 0.1 0.0 11.2 0.0 0.2 0.0 0.6 11.5 2.9 0.1 0.1 4.2 0.9 0.7 6.1 1.9 0.0 0.6 1.3 10.8 31.2 8.1 0.7 1.1 0.1 0.1 3.8 0.0 9.3 1.4 1.1 0.0 1.2 0.8 5.4 0.2 18.3 7.4 2.2 1.5 18.3 8.6 0.3 10.1 0.2 0.8 50.9 5.9 2.1 2.0 1.9 2.7 2.1 2.0 2.4 2.1 2.5 2.3 2.4 2.1 16.0 0.0 3.4 1.3 4.0 32.0 10.8 13.5 4.6 2.5 47.1 42.4 9.3 1.5 10.4 1.8 10.4 5.8 3.2 0.5 0.0 5.3 0.0 6.3 3.7 29.4 0.0 0.0 1.3 2.0 966.2 8.5 1.5 12.1 1.3 2.5 3.3 0.1 19.3 0.0 0.1 0.9 6.1 0.3 22.0 0.2 0.9 3.0 17.8 2.8 9.7 3.8 3.1 0.5 0.1 9.9 0.1 0.7 0.5 10.4 0.0 0.2 2.7 103.8 13.1 7.2 24.5 0.3 2.1 6.3 24.2 20.4 9.4 0.2 0.5 7.8 HERC3 KIAA0032 ENSG00000138641 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" Q15034 4 88592434-88708541 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 114.1" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 23.8;Cytotrophoblasts: 7.0;Extravillous trophoblasts: 17.3;Hofbauer cells: 9.3;Syncytiotrophoblasts: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 48.2;hTERT-HME1: 68.6" HPA039170 Approved Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA039170: AB_10673414" "unprognostic (2.21e-2)" "unprognostic (1.65e-2)" "unprognostic (9.28e-3)" "unprognostic (3.24e-1)" "unprognostic (6.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.30e-2)" "unprognostic (1.85e-2)" "unprognostic (9.77e-2)" "unprognostic (6.51e-3)" "unprognostic (3.48e-3)" "unprognostic (2.58e-2)" "prognostic favorable (5.65e-7)" "unprognostic (1.83e-1)" "unprognostic (3.21e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-2)" 11.6 10.2 10.6 13.3 13.4 24.3 14.0 24.5 12.5 13.3 9.4 11.4 11.6 9.9 9.6 16.5 10.2 12.0 21.9 9.6 9.5 14.9 12.1 13.6 17.1 13.6 9.4 12.0 9.3 21.1 9.4 10.1 14.0 19.5 12.1 114.1 12.1 10.9 19.3 18.2 12.1 13.6 7.8 16.1 12.8 3.2 10.0 16.8 14.5 24.4 15.0 11.0 15.3 16.8 12.2 2.4 2.4 3.8 15.3 23.9 9.0 14.5 24.2 13.0 8.5 2.8 14.8 12.0 7.9 48.2 6.1 5.2 4.4 14.1 13.0 7.2 3.4 8.9 6.3 1.9 7.9 22.6 15.7 13.2 15.4 12.7 68.6 8.9 14.2 7.5 7.8 6.2 29.5 3.8 17.8 6.7 0.4 9.6 3.9 19.7 16.5 4.5 8.3 2.6 3.4 3.2 20.4 10.7 4.6 3.9 1.9 12.2 25.7 16.7 9.6 19.9 10.4 11.5 3.1 7.5 11.5 10.2 6.1 7.8 4.9 7.3 3.8 5.6 4.4 4.3 4.7 4.0 5.4 4.2 7.0 4.4 16.2 2.4 9.2 2.4 8.1 2.9 10.6 13.4 24.5 12.5 9.6 9.5 13.6 9.4 14.0 7.8 10.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 17.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 HIC2 "HRG22, KIAA1020, ZBTB30, ZNF907" ENSG00000169635 "HIC ZBTB transcriptional repressor 2" Q96JB3 22 21417371-21451463 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 39.6;Extravillous trophoblasts: 41.4;Syncytiotrophoblasts: 39.5" "Cancer enriched" "Detected in all" 5 "testis cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 69.2;K-562: 126.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031884, HPA059399" Uncertain Supported Nucleoplasm NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA031884: AB_10602234, HPA059399: AB_2684003" "unprognostic (2.37e-1)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.42e-5)" "unprognostic (1.83e-1)" "unprognostic (3.83e-1)" "unprognostic (3.62e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-2)" "unprognostic (1.21e-4)" "unprognostic (1.28e-1)" "unprognostic (4.83e-3)" "unprognostic (7.34e-3)" "unprognostic (3.33e-1)" "unprognostic (3.86e-2)" "unprognostic (5.64e-2)" 2.2 1.2 2.5 1.4 2.6 3.7 1.5 0.8 2.8 1.7 0.0 2.1 1.3 2.0 0.5 2.6 2.2 0.8 1.5 2.7 0.9 1.7 1.8 1.8 1.5 1.0 0.6 3.4 2.1 1.1 2.6 5.8 0.9 1.2 0.8 1.5 1.4 0.7 1.1 1.5 2.1 0.7 0.2 2.4 2.4 7.4 1.0 1.7 2.4 1.1 0.9 1.1 1.5 1.4 2.2 2.7 14.4 4.3 1.1 0.9 69.2 1.4 0.5 1.4 1.2 27.2 0.8 5.1 1.4 0.9 0.9 5.9 10.2 0.9 0.8 3.4 15.0 6.8 4.0 15.0 1.2 6.0 3.1 1.1 0.5 2.1 0.9 0.7 1.1 2.1 126.9 2.1 0.7 2.1 2.7 6.2 15.3 4.8 2.0 6.7 6.4 0.8 0.7 3.6 4.0 7.0 1.8 2.1 2.6 14.9 1.2 9.0 1.9 2.2 5.4 2.1 1.6 4.2 3.6 5.4 1.8 2.5 1.5 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.3 0.0 0.0 2.5 2.6 0.8 2.8 2.7 0.9 1.0 0.6 0.9 0.2 1.0 1.4 10.3 3.2 1.1 3.6 7.7 5.5 5.4 2.6 23.9 14.8 4.7 4.2 3.9 7.2 1.7 1.8 14.6 39.6 4.4 10.0 0.0 2.6 14.2 8.3 7.6 6.5 6.1 5.7 11.8 2.6 41.4 6.6 11.2 7.6 1.3 6.4 2.9 3.0 10.3 8.4 7.5 7.4 6.1 3.8 4.3 29.9 5.6 5.6 5.4 1.9 4.5 3.0 2.1 5.0 2.3 2.8 4.6 10.1 10.4 8.1 7.0 1.6 1.5 7.3 6.6 10.7 6.0 12.2 24.5 27.1 4.5 39.5 5.8 2.6 9.3 7.5 HLA-G ENSG00000204632 "Major histocompatibility complex, class I, G" P17693 6 29826967-29831125 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 13.8;placenta: 11.1" "Cell type enriched" "Detected in many" 45 "Extravillous trophoblasts: 1850.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" CAB016158 Enhanced "Secreted to blood" NA NA 32800000 67000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016158: AB_627938" "unprognostic (1.13e-2)" "unprognostic (9.95e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (8.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-3)" "unprognostic (2.51e-1)" "prognostic favorable (3.91e-5)" "unprognostic (6.34e-2)" "unprognostic (8.31e-2)" "unprognostic (1.78e-1)" "unprognostic (1.03e-2)" "unprognostic (6.56e-3)" "unprognostic (1.40e-1)" "unprognostic (1.52e-2)" "unprognostic (3.19e-3)" 0.4 0.3 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.0 0.3 0.3 0.1 0.4 0.0 0.0 0.7 0.4 2.7 0.0 0.0 0.0 0.2 1.2 0.0 13.8 11.1 0.0 0.3 0.0 0.0 0.6 0.0 0.2 0.4 0.7 0.0 0.0 1.3 0.7 2.7 0.0 0.4 0.6 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.4 0.8 0.6 1.0 0.7 0.6 0.9 0.4 0.5 0.5 1.3 2.1 0.8 0.6 0.1 1.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.6 0.0 1.2 22.8 7.3 7.1 1.2 0.0 0.2 0.0 0.8 4.3 1.8 0.0 0.0 10.7 2.7 28.1 0.0 4.5 20.1 0.9 1.3 8.8 17.5 2.7 0.0 5.6 1850.2 5.5 1.5 2.6 0.0 0.7 6.4 1.2 25.5 0.0 0.0 34.3 2.0 8.1 27.3 13.0 2.5 4.8 12.4 0.0 1.4 0.0 3.1 0.0 0.0 24.9 19.9 2.6 0.9 14.3 0.2 0.3 0.6 0.0 0.0 4.8 3.8 5.9 2.8 0.1 35.2 40.5 6.8 1.9 18.2 15.0 HMG20B "BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL" ENSG00000064961 "High mobility group 20B" Q9P0W2 19 3572777-3579088 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 265.7;Melanocytes: 229.5;Syncytiotrophoblasts: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 411.1;WM-115: 405.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050220, HPA053157, HPA069832" Approved Enhanced Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA050220: AB_2681056, HPA053157: AB_2682061, HPA069832: AB_2686210" "unprognostic (2.97e-1)" "unprognostic (1.84e-2)" "unprognostic (2.57e-1)" "prognostic favorable (1.72e-7)" "unprognostic (2.18e-2)" "unprognostic (1.77e-2)" "unprognostic (1.12e-1)" "unprognostic (2.97e-1)" "unprognostic (1.66e-1)" "unprognostic (4.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.91e-3)" "unprognostic (2.78e-2)" "unprognostic (1.84e-1)" "prognostic favorable (2.89e-5)" 50.4 41.4 27.3 18.2 29.3 30.1 49.9 29.1 33.7 50.9 29.4 59.0 28.1 54.5 15.6 48.1 44.7 16.8 36.8 26.0 27.5 56.0 54.4 38.3 20.1 32.6 28.4 38.0 38.1 30.3 18.1 22.7 31.8 68.9 17.2 8.8 49.9 25.6 25.9 58.3 47.6 19.9 29.6 39.2 54.2 36.0 30.3 48.2 39.3 12.0 15.9 49.0 43.8 34.1 93.1 39.0 34.6 83.0 42.2 38.1 64.1 58.7 42.4 52.6 40.0 14.1 33.5 50.5 53.7 42.6 47.5 44.4 20.3 40.0 31.3 45.1 46.6 24.8 132.2 37.7 27.2 33.9 117.5 32.5 47.0 30.2 20.0 53.4 53.4 44.8 42.0 81.9 35.0 126.3 64.7 62.0 39.7 78.5 78.4 42.3 60.4 69.5 39.0 58.4 21.7 66.0 81.7 141.3 411.1 32.4 106.8 90.5 77.4 27.7 62.1 99.3 50.8 76.4 43.0 36.2 72.0 85.6 405.1 44.9 68.1 66.2 40.1 70.1 35.8 35.2 34.1 43.6 66.1 30.2 36.3 35.3 37.9 59.5 77.0 59.5 41.4 51.8 27.3 29.3 29.1 33.7 26.0 27.5 32.6 28.4 31.8 29.6 30.3 34.1 50.1 28.9 19.3 9.8 27.9 70.5 52.1 67.4 47.8 3.4 75.0 70.9 8.7 28.6 40.0 18.4 10.4 122.9 34.1 50.0 92.0 65.0 26.7 39.7 41.4 42.5 66.8 24.4 0.7 45.5 265.7 35.4 32.6 44.4 37.5 58.1 38.6 20.9 81.9 8.4 0.7 170.8 57.0 29.6 93.4 49.6 37.3 47.1 229.5 3.7 86.2 41.2 42.2 0.5 11.7 58.6 68.5 44.8 34.9 62.8 74.7 76.2 29.5 18.7 32.9 22.4 53.4 39.9 17.4 53.0 79.8 303.7 30.8 49.6 68.7 62.9 HROB "C17orf53, MCM8IP, MGC3130" ENSG00000125319 "Homologous recombination factor with OB-fold" Q8N3J3 17 44141906-44162476 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA synthesis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.3;testis: 11.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.3;Cytotrophoblasts: 3.4;Extravillous trophoblasts: 8.6;Hofbauer cells: 2.9;Syncytiotrophoblasts: 1.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023004, HPA023393, HPA024430" Uncertain Approved Nucleoplasm,Cytosol NA Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "HPA023004: AB_1853877, HPA023393: AB_1853878, HPA024430: AB_1853879" "unprognostic (1.72e-1)" "unprognostic (5.95e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.59e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (3.46e-4)" "prognostic unfavorable (9.39e-4)" "unprognostic (1.90e-1)" "unprognostic (2.89e-1)" "unprognostic (3.66e-4)" "unprognostic (2.86e-1)" "unprognostic (0.00e+0)" "unprognostic (3.06e-2)" "unprognostic (5.88e-2)" "unprognostic (3.65e-2)" "unprognostic (8.40e-2)" 1.5 0.4 0.1 1.1 0.1 9.3 1.4 0.4 0.3 0.9 0.0 0.9 0.9 0.8 0.1 2.7 0.5 0.2 0.7 0.1 0.2 0.4 0.6 0.6 1.6 0.3 0.2 0.8 0.3 0.4 0.4 0.9 0.3 0.7 1.0 0.3 0.7 0.3 0.9 1.7 0.9 0.7 0.1 1.3 0.6 11.4 0.2 2.3 0.3 0.2 1.9 0.6 1.2 0.3 8.9 11.1 8.3 7.6 0.6 2.3 9.8 6.7 5.9 12.8 13.9 11.3 5.4 9.4 5.8 5.8 13.3 7.5 10.9 10.5 11.1 10.6 14.0 6.0 10.1 7.7 0.3 6.6 7.3 1.9 1.6 15.7 7.7 1.5 5.3 10.2 13.8 11.6 6.2 6.7 15.7 10.2 5.6 4.0 10.8 10.0 13.2 11.6 3.0 7.0 5.1 2.9 4.1 4.0 3.4 9.4 8.1 7.7 2.4 12.1 9.5 8.3 9.9 6.7 12.2 8.0 5.7 5.1 7.1 0.0 0.2 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.9 0.4 0.1 0.1 0.1 0.4 0.3 0.1 0.2 0.3 0.2 0.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974228-38988663 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 67.0" "Cell type enriched" "Detected in some" 10 "Extravillous trophoblasts: 444.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "BEWO: 233.6" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" NA NA 23000 "Cluster 17: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA045402: AB_2679316" "unprognostic (1.20e-1)" "unprognostic (5.83e-4)" "unprognostic (8.02e-2)" "unprognostic (2.13e-2)" "unprognostic (8.20e-2)" "unprognostic (2.42e-2)" "unprognostic (1.80e-1)" "unprognostic (7.40e-3)" "unprognostic (1.40e-1)" "unprognostic (5.14e-4)" "unprognostic (1.01e-1)" "unprognostic (8.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.58e-1)" "unprognostic (5.19e-3)" "unprognostic (2.39e-3)" "unprognostic (1.19e-3)" 0.8 0.5 0.8 0.8 1.2 7.2 1.2 3.5 5.0 0.9 0.0 0.5 0.3 0.9 0.9 0.1 0.3 0.5 0.3 1.3 0.9 0.4 0.5 2.0 2.5 0.6 0.5 0.6 0.8 0.5 0.1 67.0 0.6 0.6 0.7 1.8 0.3 1.1 1.0 0.8 0.4 0.7 0.1 1.2 0.4 0.9 1.4 0.5 0.5 0.1 1.7 0.4 0.1 2.0 0.4 0.3 0.2 0.4 0.8 0.4 233.6 0.6 0.4 0.3 0.4 0.4 0.5 0.5 0.2 0.2 0.4 0.4 0.2 0.2 0.1 0.2 0.4 0.4 0.7 0.3 0.2 0.6 0.6 0.7 0.2 0.2 0.5 0.3 0.2 0.2 0.4 1.3 0.2 0.5 0.4 0.3 0.3 0.1 0.2 0.2 0.2 0.4 0.2 0.7 0.4 0.6 0.5 0.3 0.1 9.6 0.5 0.7 0.0 0.7 0.5 0.3 0.3 0.5 0.2 0.2 0.2 0.7 0.2 0.3 0.1 0.4 0.2 0.1 0.3 0.2 0.2 0.2 0.1 0.5 0.2 0.2 0.5 0.2 0.2 0.5 0.3 0.0 0.8 1.2 3.5 5.0 1.3 0.9 0.6 0.5 0.6 0.1 1.4 2.0 0.1 0.0 0.0 0.0 1.0 0.1 1.7 0.1 1.2 0.5 0.1 0.3 0.7 0.0 0.0 0.0 2.1 2.8 1.1 0.1 0.0 0.0 0.1 0.2 0.7 0.3 0.0 0.0 0.4 0.0 444.0 1.2 0.0 0.5 0.0 0.7 1.4 0.0 11.6 1.7 0.2 0.0 0.0 0.6 0.3 0.0 0.0 3.8 1.8 1.0 0.0 0.4 1.0 1.5 0.2 0.3 0.0 0.0 0.5 1.5 0.0 0.2 0.1 0.2 0.0 3.5 0.2 0.0 0.1 0.0 0.1 40.4 0.7 0.2 0.2 1.1 HYAL4 ENSG00000106302 "Hyaluronidase 4" Q2M3T9 7 123828983-123877481 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 4.0;skeletal muscle: 3.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.8;Cytotrophoblasts: 4.3;Extravillous trophoblasts: 8.1;Spermatogonia: 4.4;Syncytiotrophoblasts: 2.2" "Cancer enriched" "Detected in single" 48 "testis cancer: 8.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;CAPAN-2: 5.9;RT4: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA029453 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA029453: AB_10601432" "unprognostic (5.19e-5)" "unprognostic (4.18e-2)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (2.60e-1)" "unprognostic (8.24e-2)" "unprognostic (5.26e-2)" "unprognostic (8.15e-3)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (5.55e-3)" 0.1 0.1 0.6 0.0 0.7 0.5 0.1 1.0 1.0 0.1 0.5 0.2 0.0 0.1 0.4 0.4 0.0 0.1 0.2 0.7 0.4 0.4 0.1 0.4 0.2 0.5 0.3 0.2 0.5 0.0 0.0 4.0 0.7 0.2 0.1 1.0 0.5 0.2 3.9 0.9 0.2 0.0 0.1 0.8 0.2 2.1 0.5 0.0 0.4 0.0 1.0 0.2 0.0 1.3 0.2 0.4 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 5.9 0.2 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.1 0.0 13.9 0.2 0.0 0.0 0.8 0.0 1.1 0.2 0.0 2.0 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.2 0.1 0.1 0.0 0.0 0.6 0.7 1.0 1.0 0.7 0.4 0.5 0.3 0.7 0.1 0.5 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 8.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 1.3 4.4 0.0 0.0 2.2 0.0 0.0 0.0 0.2 ICMT "HSTE14, PCCMT, PPMT" ENSG00000116237 "Isoprenylcysteine carboxyl methyltransferase" O60725 1 6221193-6235972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 112.8" "Low region specificity" "Detected in all" "HPA032024, HPA032025" Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA032024: AB_2674115, HPA032025: AB_10601819" "unprognostic (1.95e-3)" "unprognostic (3.83e-2)" "unprognostic (7.34e-2)" "unprognostic (4.40e-2)" "unprognostic (5.53e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.30e-2)" "unprognostic (7.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (6.58e-2)" "unprognostic (2.11e-2)" "unprognostic (4.11e-1)" "unprognostic (5.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.99e-3)" 22.6 23.0 12.4 13.6 18.1 4.0 15.8 18.2 13.1 20.3 17.7 20.9 19.6 20.1 20.9 21.6 16.2 13.1 27.1 12.5 12.9 25.9 13.6 14.9 10.2 12.6 14.9 9.1 17.4 26.8 22.0 21.0 12.7 17.3 17.4 28.7 17.1 18.9 53.0 19.2 18.3 21.9 12.3 9.1 15.7 5.2 14.5 14.9 18.1 82.6 11.0 17.4 16.0 12.0 35.8 32.6 43.7 43.0 131.2 51.8 18.7 84.9 56.1 48.7 36.9 35.0 28.2 39.0 31.7 66.7 42.0 47.4 50.5 35.6 51.5 78.8 51.3 26.8 46.0 26.8 25.5 42.5 36.4 33.3 23.5 51.2 19.2 32.4 38.5 31.6 26.5 29.8 55.7 22.3 43.2 29.6 29.7 64.1 46.0 35.8 61.5 22.6 59.3 25.8 59.2 28.8 41.3 96.3 37.2 48.4 25.2 35.4 48.1 55.3 21.7 65.4 61.6 27.7 57.8 30.5 27.1 96.5 29.3 2.6 1.9 1.6 3.1 2.2 2.7 1.1 2.5 3.1 1.7 1.8 2.1 1.8 0.6 1.8 1.9 2.7 1.4 1.9 12.4 18.1 18.2 13.1 12.5 12.9 12.6 14.9 12.7 12.3 14.5 12.0 18.0 22.4 12.1 5.9 7.7 6.2 9.6 12.2 7.4 18.0 16.3 9.8 39.3 15.7 19.6 29.5 31.3 57.6 12.3 40.7 13.7 21.9 3.5 19.5 18.8 18.1 22.8 14.9 10.2 22.2 85.7 19.6 12.8 16.9 5.1 13.9 21.8 23.9 29.1 48.8 9.4 21.4 12.2 12.0 7.0 5.1 20.8 9.8 7.2 7.5 12.1 18.9 10.3 2.0 5.4 26.8 12.2 26.4 18.3 14.1 45.5 36.9 41.7 58.8 13.1 9.9 22.1 15.4 26.8 28.2 10.4 32.0 10.4 13.9 23.1 14.7 IGF2BP3 "CT98, IMP-3, IMP3" ENSG00000136231 "Insulin like growth factor 2 mRNA binding protein 3" O00425 7 23310209-23470491 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.3;placenta: 28.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 84.8;Early spermatids: 40.8;Extravillous trophoblasts: 93.4;Hofbauer cells: 38.5;Late spermatids: 24.1;Syncytiotrophoblasts: 78.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 170.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002037, HPA076951" Enhanced Supported Cytosol NA NA 27000 "Cluster 24: B-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA002037: AB_1851483, HPA076951: " "unprognostic (5.72e-2)" "unprognostic (3.12e-1)" "unprognostic (7.25e-2)" "unprognostic (3.56e-3)" "unprognostic (1.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.64e-3)" "unprognostic (3.18e-2)" "unprognostic (2.60e-3)" "unprognostic (3.67e-1)" "unprognostic (1.02e-5)" "unprognostic (8.76e-2)" "unprognostic (0.00e+0)" "unprognostic (1.43e-1)" "unprognostic (7.95e-2)" "unprognostic (2.87e-4)" "unprognostic (7.51e-3)" 0.3 0.0 0.6 0.8 0.3 0.6 0.1 0.2 0.4 0.1 0.0 0.1 0.0 0.0 0.8 2.1 0.9 0.2 0.0 0.3 0.0 0.0 0.5 0.5 4.2 0.0 0.0 0.0 0.6 0.3 0.0 28.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 5.1 0.3 1.6 0.8 0.1 7.3 0.2 0.2 0.1 48.7 14.0 104.5 31.0 16.2 42.8 63.7 8.1 35.7 19.6 24.2 45.0 37.4 36.4 42.1 21.3 86.4 31.2 45.8 35.2 34.2 5.9 18.3 19.3 38.1 37.9 50.3 35.5 13.1 44.1 24.2 15.0 6.3 114.7 170.0 20.0 89.5 0.2 47.8 0.0 21.6 23.5 83.0 36.6 43.3 33.2 34.8 47.1 38.4 4.2 27.4 59.6 4.8 0.3 38.9 118.3 0.0 6.6 68.9 18.6 1.2 40.6 21.0 0.0 15.8 56.7 73.8 38.6 72.8 0.0 0.4 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 1.0 2.8 0.3 0.7 0.3 0.0 0.5 0.0 0.0 0.5 0.0 0.3 0.0 0.0 84.8 1.4 0.1 0.0 1.2 40.8 5.4 0.2 1.7 0.0 0.0 2.0 0.2 93.4 3.5 0.0 1.5 3.8 0.1 1.1 0.2 38.5 1.7 12.9 0.0 0.0 0.8 0.6 24.1 2.1 11.3 3.6 5.6 2.9 0.2 2.1 1.5 1.8 1.0 0.0 0.0 2.1 0.2 0.0 0.1 2.6 1.6 0.0 0.4 7.7 6.8 3.5 0.7 0.4 78.5 0.3 0.0 0.0 0.6 IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" 21.9 19.1 97.9 14.0 119.0 3.7 26.7 91.7 130.7 25.7 39.9 31.7 26.5 19.8 22.7 22.3 28.2 12.3 29.0 106.0 82.4 35.5 53.9 23.6 16.8 109.3 97.8 37.5 31.8 15.8 30.7 11.2 99.9 26.4 10.4 14.3 30.1 18.2 12.4 50.3 28.5 7.0 98.6 24.2 27.5 33.4 94.7 13.6 28.6 7.1 8.9 20.3 25.0 155.3 26.8 15.7 20.1 51.3 11.6 7.3 42.9 12.9 16.8 26.9 25.0 17.9 17.9 39.0 47.1 18.8 23.4 50.3 8.2 18.9 3.8 47.3 15.0 5.1 17.3 31.2 19.2 13.5 41.7 9.0 37.7 17.5 5.6 19.0 5.6 42.0 7.0 21.8 6.3 25.4 33.8 31.3 42.4 55.6 24.8 19.1 10.3 28.7 24.7 27.4 8.5 36.6 14.8 47.4 177.6 17.5 33.7 17.3 5.8 11.8 25.4 21.5 10.6 59.6 71.2 17.7 41.6 5.3 31.6 0.1 5.2 2.4 22.0 7.2 19.5 19.6 18.0 25.6 5.8 22.7 23.4 25.7 1.4 9.2 4.7 9.9 26.9 11.3 97.9 119.0 91.7 130.7 106.0 82.4 109.3 97.8 99.9 98.6 94.7 155.3 12.2 9.6 3.3 18.3 21.1 43.7 30.2 43.1 26.2 55.6 28.0 29.2 3.3 17.2 16.7 38.6 10.4 32.8 15.1 36.1 5.9 34.2 3.8 12.0 7.2 7.8 19.9 7.4 65.3 12.4 219.7 22.4 6.6 26.4 10.2 12.2 13.2 28.8 14.9 65.6 43.8 24.7 44.7 4.3 16.2 1.1 16.8 8.5 42.7 9.4 51.5 75.7 10.3 9.0 107.2 20.6 39.5 15.8 20.0 22.0 47.6 15.8 6.0 11.8 6.6 39.8 15.3 4.0 6.6 21.0 62.4 69.4 19.5 13.6 32.6 26.0 ISM2 "FLJ32147, TAIL1, THSD3" ENSG00000100593 "Isthmin 2" Q6H9L7 14 77474394-77498816 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "placenta: 213.4" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 291.0;Extravillous trophoblasts: 617.2;Syncytiotrophoblasts: 177.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "BEWO: 386.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039314, HPA039742" Supported Supported Nucleoplasm "Secreted in female reproductive system" NA NA 1100000 "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA039314: AB_10673239, HPA039742: AB_10673427" "unprognostic (5.69e-2)" "unprognostic (9.17e-3)" "unprognostic (2.58e-2)" "unprognostic (1.41e-3)" "unprognostic (3.73e-2)" "unprognostic (2.34e-1)" "unprognostic (2.16e-2)" "unprognostic (3.09e-3)" "unprognostic (2.11e-1)" "unprognostic (4.13e-1)" "unprognostic (8.10e-2)" "unprognostic (1.42e-2)" "unprognostic (9.36e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (3.95e-1)" 0.6 0.0 0.3 0.1 1.2 0.0 0.0 0.0 0.7 0.8 0.8 0.2 0.1 1.2 3.7 0.2 0.4 0.1 0.1 0.2 0.6 0.7 0.0 0.0 0.0 0.1 0.3 0.1 0.6 0.4 0.5 213.4 0.2 1.8 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.6 0.8 0.0 0.2 0.0 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 386.3 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.3 0.5 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.7 0.2 0.6 0.1 0.3 0.2 0.1 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 291.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.0 617.2 2.1 0.0 0.0 0.0 0.1 0.0 0.0 33.4 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 1.7 0.0 0.0 177.5 0.0 0.0 0.0 0.0 ITGA5 "CD49e, FNRA" ENSG00000161638 "Integrin subunit alpha 5" P08648 12 54395261-54419266 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 398.8;smooth muscle: 361.9;urinary bladder: 386.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 101.5;Extravillous trophoblasts: 391.9;Hepatic stellate cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 615.4;HUVEC TERT2: 1360.8;TIME: 1277.7;U-87 MG: 623.6" "Region enriched" "Detected in many" 5 "basal ganglia: 10.4" "Low region specificity" "Detected in many" "HPA002642, CAB009008" Enhanced NA NA 26000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB009008: AB_647474, HPA002642: AB_1078469" "unprognostic (7.51e-3)" "prognostic unfavorable (4.07e-6)" "prognostic unfavorable (8.43e-4)" "unprognostic (1.58e-1)" "unprognostic (8.51e-3)" "prognostic unfavorable (2.91e-4)" "prognostic unfavorable (2.23e-5)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.76e-2)" "unprognostic (6.19e-2)" "unprognostic (8.99e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (1.32e-8)" "unprognostic (2.11e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.89e-4)" "unprognostic (2.18e-3)" 114.4 47.1 8.7 136.2 9.2 46.4 69.1 9.2 13.8 64.0 9.7 398.8 15.3 106.1 5.0 72.3 71.1 50.8 113.9 8.5 9.0 26.6 48.6 121.7 17.5 11.3 9.9 39.3 20.9 14.9 10.5 91.6 11.3 141.9 40.6 1.3 24.5 114.9 29.1 50.5 87.6 361.9 10.6 16.3 90.8 4.0 17.1 13.2 40.5 25.7 12.5 386.5 76.9 9.8 65.4 23.9 43.6 0.6 130.8 278.7 113.5 286.0 308.2 300.9 220.6 17.1 15.3 0.5 206.9 308.5 149.1 10.1 12.5 81.4 197.4 0.4 12.2 28.1 31.3 1.1 179.5 88.7 44.4 206.8 39.2 351.9 258.3 615.4 1360.8 15.6 25.6 0.8 165.4 6.4 13.7 99.2 18.1 4.2 19.1 13.7 29.2 6.2 46.9 1.1 0.1 0.6 57.7 4.3 2.2 93.8 7.1 79.9 1277.7 353.0 62.3 85.9 121.5 0.3 3.6 0.7 623.6 83.0 118.5 16.4 64.9 0.5 14.2 27.3 11.2 0.1 10.9 10.9 62.6 0.3 7.7 6.6 89.1 26.4 24.0 3.4 4.9 42.9 8.7 9.2 9.2 13.8 8.5 9.0 11.3 9.9 11.3 10.6 17.1 9.8 58.3 3.2 4.4 1.6 2.7 14.3 3.4 11.3 4.0 1.1 6.1 2.8 16.3 14.3 4.9 0.0 0.0 5.4 19.6 0.0 0.0 34.0 0.3 1.7 32.1 101.5 0.0 3.4 1.4 3.4 391.9 45.0 0.5 3.0 19.7 5.1 88.9 27.1 28.4 0.0 1.2 0.0 2.0 22.8 58.5 0.5 6.5 38.5 10.6 14.0 24.6 0.0 21.6 0.0 0.2 8.8 0.0 4.5 8.7 3.6 0.0 0.2 1.8 1.1 13.1 11.1 30.7 0.2 0.7 1.3 10.7 34.6 14.3 2.4 0.0 2.0 JPT2 "C16orf34, FLJ13092, HN1L, KIAA1426, L11" ENSG00000206053 "Jupiter microtubule associated homolog 2" Q9H910 16 1678256-1702280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 99.3;Ductal cells: 90.1;Endometrial ciliated cells: 107.3;Extravillous trophoblasts: 205.9;Glandular and luminal cells: 77.5;Pancreatic endocrine cells: 78.9;Syncytiotrophoblasts: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041888, HPA041908" Approved Approved "Plasma membrane,Cytosol" NA NA 76000 "Cluster 22: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041888: AB_10793937, HPA041908: AB_10794160" "unprognostic (1.49e-2)" "unprognostic (1.76e-1)" "unprognostic (1.30e-3)" "prognostic favorable (7.85e-4)" "unprognostic (3.60e-1)" "unprognostic (2.37e-2)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.10e-2)" "unprognostic (3.14e-2)" "unprognostic (1.50e-2)" "unprognostic (1.12e-3)" "unprognostic (4.27e-2)" "unprognostic (1.01e-2)" "unprognostic (9.22e-3)" "unprognostic (1.65e-1)" "unprognostic (4.14e-2)" "unprognostic (2.78e-2)" 21.2 17.0 12.7 18.6 21.1 11.3 36.4 33.2 19.8 39.5 14.1 32.7 21.9 21.1 17.9 47.7 63.4 13.6 20.3 12.0 16.3 48.8 41.1 20.0 19.9 58.0 27.8 19.8 29.6 20.9 15.1 48.1 46.9 47.9 30.5 4.6 26.6 18.2 17.5 31.3 24.2 19.5 28.4 12.8 28.2 18.1 25.6 35.5 27.7 14.0 31.3 31.2 25.9 51.7 148.1 147.5 168.4 93.9 23.9 39.3 151.9 143.6 44.8 117.7 99.8 194.5 188.3 94.6 107.8 71.1 116.4 141.9 223.5 194.2 135.7 77.2 135.2 78.4 80.2 111.4 36.7 93.5 44.8 28.1 121.6 116.4 149.6 64.9 75.7 85.4 187.5 37.0 68.6 169.5 117.1 46.6 185.3 164.4 112.0 212.7 159.3 136.2 186.2 82.5 156.1 85.6 214.9 205.3 66.5 161.1 250.3 59.6 87.9 113.9 201.1 54.8 141.1 31.5 136.3 198.8 35.8 71.5 170.5 2.1 3.7 4.1 5.2 3.3 7.2 4.8 5.8 4.2 2.8 7.6 6.3 5.4 0.3 6.8 1.7 6.6 5.8 4.4 12.7 21.1 33.2 19.8 12.0 16.3 58.0 27.8 46.9 28.4 25.6 51.7 11.9 25.6 10.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 33.3 23.4 0.0 0.0 12.4 9.2 0.0 99.3 4.5 0.0 43.0 90.1 0.0 107.3 19.2 8.5 0.0 0.0 0.0 25.6 205.9 7.4 0.0 77.5 2.5 23.4 0.0 0.0 41.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 28.4 0.0 0.0 0.0 0.0 78.9 0.0 0.0 1.2 0.0 0.0 26.0 27.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 168.7 3.6 18.9 0.0 0.0 KAT14 "ATAC2, CRP2BP, CSRP2BP, dJ717M23.1, PRO1194" ENSG00000149474 "Lysine acetyltransferase 14" Q9H8E8 20 18137228-18188387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 17.5;Extravillous trophoblasts: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 87.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068443 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA068443: AB_2685990" "unprognostic (4.02e-2)" "unprognostic (1.17e-1)" "unprognostic (8.60e-2)" "unprognostic (9.38e-2)" "unprognostic (3.98e-1)" "unprognostic (1.90e-2)" "unprognostic (3.37e-2)" "unprognostic (3.21e-1)" "unprognostic (4.04e-1)" "unprognostic (2.29e-1)" "unprognostic (7.15e-3)" "unprognostic (1.96e-2)" "prognostic favorable (4.64e-5)" "unprognostic (4.51e-1)" "unprognostic (4.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" 6.4 8.4 8.9 4.5 9.5 2.0 7.9 8.9 9.9 7.6 7.6 9.8 8.8 7.8 10.5 7.1 9.4 5.2 7.3 9.8 9.0 9.0 8.3 4.7 7.4 8.0 8.3 10.8 8.0 10.3 7.9 8.3 7.9 7.5 8.8 7.2 7.9 8.0 20.8 9.9 8.5 7.7 8.3 7.7 11.2 8.6 10.3 11.3 8.3 16.6 7.8 8.8 7.4 9.3 8.9 12.9 10.1 9.7 13.4 11.2 87.5 8.4 12.1 11.2 11.1 46.7 11.8 20.7 5.1 7.0 15.9 10.8 10.3 8.9 8.9 8.0 4.1 13.0 3.6 7.4 11.0 12.4 8.5 9.2 16.1 6.7 12.7 10.0 9.1 16.9 7.4 10.6 11.1 10.7 22.1 7.0 14.9 20.4 12.2 11.1 25.1 8.2 10.7 5.3 13.8 8.7 10.8 24.8 13.8 9.2 10.4 11.1 7.7 10.5 4.1 7.4 6.3 9.2 19.0 11.1 3.4 6.0 11.3 0.6 5.7 1.8 9.1 5.7 10.8 7.9 9.2 10.8 8.5 9.8 12.9 10.0 0.5 10.7 11.1 5.9 5.9 8.4 8.9 9.5 8.9 9.9 9.8 9.0 8.0 8.3 7.9 8.3 10.3 9.3 3.1 9.6 6.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 4.3 3.9 0.0 0.0 4.3 1.8 0.0 17.5 1.6 0.0 1.9 4.5 0.0 6.9 5.8 2.1 0.0 0.0 0.0 6.4 38.2 2.3 0.0 5.8 3.8 8.3 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.3 0.0 0.0 6.9 4.4 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 4.1 1.6 7.9 0.0 0.0 KCNK12 "K2p12.1, THIK-2, THIK2" ENSG00000184261 "Potassium two pore domain channel subfamily K member 12" Q9HB15 2 47509290-47570985 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 7.0;pituitary gland: 3.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.2;Cone photoreceptor cells: 14.6;Excitatory neurons: 19.0;Extravillous trophoblasts: 33.7;Inhibitory neurons: 30.4;NK-cells: 11.3" "Cancer enriched" "Detected in single" 12 "testis cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "REH: 10.5;SCLC-21H: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 6: Brain - Smell perception" "Cluster 14: REH - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (6.10e-2)" "unprognostic (1.24e-1)" "unprognostic (6.02e-3)" "unprognostic (3.29e-2)" "unprognostic (2.50e-1)" "unprognostic (3.77e-2)" "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (2.54e-2)" "unprognostic (2.14e-1)" "unprognostic (6.55e-3)" "unprognostic (2.12e-1)" "unprognostic (1.12e-6)" "unprognostic (1.36e-1)" "unprognostic (1.34e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-1)" 0.1 0.1 1.5 0.1 1.2 0.1 0.0 7.0 5.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.3 0.0 0.0 0.0 0.1 3.0 0.4 0.0 0.0 0.0 3.5 0.1 2.9 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.6 0.0 0.3 10.5 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 1.2 7.0 5.6 1.5 0.3 3.0 0.4 2.9 0.9 1.0 2.4 0.2 0.0 0.0 0.3 3.2 0.1 0.1 0.0 0.0 10.2 0.2 0.3 1.3 0.0 0.0 0.0 14.6 0.2 2.6 0.0 0.0 0.0 8.3 0.2 0.4 0.1 0.0 0.4 19.0 0.0 33.7 0.3 0.5 0.1 0.0 1.0 0.0 0.0 0.4 1.7 30.4 0.0 0.0 0.3 0.4 5.2 0.3 0.0 0.0 0.0 0.1 0.6 11.3 1.0 8.2 0.0 0.0 0.4 4.7 0.6 0.0 0.1 0.0 5.3 0.0 0.2 0.4 3.9 2.5 0.0 0.0 0.8 3.0 1.3 0.0 0.1 KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921005 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 8.5" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 41.9" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 15.7;RPMI-8226: 37.4;SCLC-21H: 7.4;SH-SY5Y: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA007156: , HPA071913: AB_2686471" "unprognostic (1.54e-1)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.15e-1)" "unprognostic (8.46e-3)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "prognostic unfavorable (3.33e-6)" "unprognostic (1.87e-1)" "unprognostic (8.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" 0.0 0.0 2.9 0.1 1.8 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 3.8 0.3 0.1 0.1 0.1 4.0 2.2 0.0 1.3 0.3 1.1 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.4 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.3 4.1 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.7 0.0 0.0 0.3 0.1 0.0 0.6 1.2 0.4 1.0 0.0 37.4 0.0 0.0 7.4 20.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.9 1.8 0.9 3.4 1.3 3.8 4.0 2.2 3.9 1.0 8.5 0.8 0.1 0.0 0.0 0.0 1.0 0.1 0.1 0.5 0.0 1.1 1.2 1.4 0.5 0.0 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.2 41.9 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.8 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.0 0.0 4.2 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.0 0.3 0.3 0.3 1.6 0.9 0.2 0.1 0.2 KRT33B "Ha-3II, KRTHA3B" ENSG00000131738 "Keratin 33B" Q14525 17 41363498-41369813 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "skin 1: 82.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 2.9;Ionocytes: 2.0" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "BJ: 4.3;BJ hTERT+ SV40 Large T+ RasG12V: 1.1" HPA055194 Supported NA NA 350000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA055194: AB_2682733" "unprognostic (3.34e-2)" "unprognostic (5.19e-2)" "unprognostic (3.04e-1)" "unprognostic (1.55e-2)" "unprognostic (6.28e-2)" 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 KRT9 "CK-9, EPPK, K9" ENSG00000171403 "Keratin 9" P35527 17 41565836-41572059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 12.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.4;Breast myoepithelial cells: 2.9;Extravillous trophoblasts: 2.2" "Cancer enriched" "Detected in some" 6 "melanoma: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.0;HaCaT: 16.8;U-2197: 3.0;U-937: 5.3" "Region enhanced" "Detected in many" "basal ganglia: 25.1" "HPA007261, CAB037322" Supported NA NA 24000000000 "Cluster 63: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB037322: , HPA007261: AB_1079182" "unprognostic (2.13e-2)" "unprognostic (5.08e-2)" "unprognostic (4.97e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (5.92e-7)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-2)" 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.5 0.1 0.1 0.1 0.0 0.0 0.2 0.0 12.1 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.9 0.0 0.0 0.0 0.1 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.2 KRTAP2-2 KAP2.2 ENSG00000214518 "Keratin associated protein 2-2" Q9BYT5 17 41054498-41055230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 337 "skin 1: 54.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA059203: AB_2683947" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LAIR2 CD306 ENSG00000167618 "Leukocyte associated immunoglobulin like receptor 2" Q6ISS4 19 54497879-54510687 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.6;pituitary gland: 2.6" "Cell type enriched" "Detected in some" 7 "Extravillous trophoblasts: 696.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "gdT-cell: 14.0;memory CD4 T-cell: 13.8;memory CD8 T-cell: 19.5;naive CD8 T-cell: 13.2;T-reg: 49.5" "Lineage enriched" "Detected in many" 40 "T-cells: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Hep G2: 1.0" "Low region specificity" "Detected in some" "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.99e-3)" "unprognostic (7.49e-2)" "unprognostic (4.19e-2)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (4.86e-4)" "unprognostic (1.06e-2)" "unprognostic (8.37e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" "unprognostic (3.68e-9)" "unprognostic (1.21e-2)" "unprognostic (3.15e-3)" "unprognostic (3.40e-5)" "unprognostic (6.71e-2)" 0.2 0.0 0.1 0.4 0.3 0.8 0.1 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.1 0.7 1.6 0.2 0.2 0.0 0.1 0.0 2.6 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.1 0.3 0.3 0.4 0.6 0.1 0.2 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 14.0 0.1 0.4 0.0 13.8 19.5 0.1 0.1 2.4 13.2 0.2 1.2 0.3 0.1 49.5 7.8 0.1 0.3 0.1 0.7 0.3 0.3 0.2 0.2 0.4 0.1 0.4 0.5 0.8 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 10.7 95.4 0.9 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.2 696.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.8 1.8 0.0 0.5 0.0 46.4 0.0 0.1 0.6 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 32.2 23.2 0.0 0.0 0.0 LIN28B "CSDD2, FLJ16517" ENSG00000187772 "Lin-28 homolog B" Q6ZN17 6 104936616-105083332 "Predicted intracellular proteins" "RNA-mediated gene silencing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "placenta: 65.4" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 75.4;Early spermatids: 27.5;Excitatory neurons: 40.2;Extravillous trophoblasts: 83.0;Late spermatids: 25.2;Syncytiotrophoblasts: 55.8" "Cancer enriched" "Detected in single" 25 "testis cancer: 12.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 49.1;BEWO: 252.1;Hep G2: 44.0;K-562: 86.9;NTERA-2: 44.8;SuSa: 44.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA036630, HPA061745" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA036630: AB_10669911, HPA061745: AB_2684601" "unprognostic (2.00e-4)" "unprognostic (6.75e-2)" "unprognostic (2.02e-1)" "unprognostic (2.57e-2)" "unprognostic (1.59e-2)" "unprognostic (4.10e-2)" 0.1 0.1 0.4 0.0 0.8 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.3 65.4 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 4.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 3.2 49.1 10.0 0.0 0.0 252.1 0.1 0.0 0.0 0.0 16.6 0.1 0.1 0.0 0.1 3.0 0.1 31.2 0.0 0.0 0.0 24.1 36.6 0.0 44.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 86.9 1.2 0.0 0.0 5.6 6.2 44.8 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.1 11.6 0.1 0.3 4.0 44.5 0.0 10.6 1.0 0.1 5.3 0.2 0.1 14.8 22.6 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.8 0.0 1.3 0.6 0.7 0.4 0.2 0.1 0.0 0.3 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 6.2 75.4 0.0 0.0 0.0 0.0 27.5 0.0 0.0 8.3 0.0 0.0 40.2 0.0 83.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 9.7 1.7 5.7 0.0 0.0 0.0 0.0 25.2 0.3 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 6.6 0.0 0.0 6.3 9.9 0.0 0.0 55.8 0.0 0.0 0.0 0.0 LY6E "RIG-E, SCA-2, TSA-1" ENSG00000160932 "Lymphocyte antigen 6 family member E" Q16553 8 143017982-143023832 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 614.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1386.5;Extravillous trophoblasts: 4724.2;Granulosa cells: 998.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 753.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 627.1;BJ hTERT+ SV40 Large T+ RasG12V: 888.7;MCF7: 878.7" "Intracellular and membrane" NA NA 44000 "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "unprognostic (3.88e-2)" "unprognostic (3.70e-3)" "unprognostic (9.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" "unprognostic (6.64e-2)" "unprognostic (4.94e-1)" "unprognostic (7.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (6.74e-8)" "unprognostic (2.68e-1)" "unprognostic (2.28e-3)" "unprognostic (1.84e-3)" "unprognostic (2.12e-2)" 221.7 248.1 95.6 47.9 99.3 120.5 205.6 94.4 133.8 218.1 89.1 80.1 24.8 143.5 36.9 187.1 157.0 85.9 141.1 117.3 92.8 214.6 614.0 232.2 40.6 101.0 89.9 199.3 58.4 23.1 92.5 88.8 92.1 143.1 15.3 4.8 140.4 47.3 38.4 130.2 79.0 50.2 103.5 218.3 72.7 52.4 96.3 56.5 94.7 37.6 30.3 107.6 159.2 91.8 75.8 114.5 2.4 98.9 147.9 267.8 161.4 174.7 504.5 627.1 888.7 1.8 204.3 19.2 122.0 214.8 75.1 216.2 60.2 102.7 72.5 13.4 17.9 76.0 54.1 75.5 106.3 7.0 45.0 230.3 37.4 96.1 42.3 68.5 37.9 32.2 17.9 248.8 45.1 878.7 49.0 56.9 41.0 439.2 34.5 32.2 0.8 98.4 153.8 82.3 94.8 12.8 142.3 216.1 231.9 96.3 236.8 44.7 7.2 26.9 66.4 73.9 0.9 1.0 4.7 1.9 56.6 27.4 96.7 14.0 124.4 15.4 186.5 565.5 71.2 129.5 137.1 123.6 72.8 160.1 75.8 125.7 34.8 272.7 753.3 7.6 121.3 241.1 95.6 99.3 94.4 133.8 117.3 92.8 101.0 89.9 92.1 103.5 96.3 91.8 318.1 22.4 13.4 3.3 141.6 175.5 427.7 528.1 255.6 8.7 301.7 492.0 4.5 255.9 440.5 46.0 0.0 1386.5 149.6 2.4 23.5 298.8 3.8 13.5 233.3 312.0 29.3 76.6 21.4 22.7 4724.2 295.8 43.3 18.9 53.3 998.5 151.0 314.0 365.9 47.1 13.1 20.1 130.2 104.3 225.3 10.0 289.8 176.4 158.3 26.2 111.5 18.7 436.7 5.5 3.6 196.8 0.6 222.3 121.6 240.5 2.0 212.3 112.8 3.6 144.7 34.9 151.6 1.5 45.1 238.6 117.3 534.3 229.6 99.8 14.4 593.7 MACIR "C5orf30, FLJ25291" ENSG00000181751 "Macrophage immunometabolism regulator" Q96GV9 5 103258763-103278660 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Inflammatory response, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.6" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 37.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.6" "Cell line enhanced" "Detected in many" "BJ: 177.1;fHDF/TERT166: 108.5;U-138 MG: 115.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043434 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA043434: AB_2678480" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (6.59e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.85e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (1.78e-5)" "unprognostic (1.15e-1)" "unprognostic (3.85e-2)" "unprognostic (8.76e-2)" "unprognostic (4.36e-2)" "unprognostic (1.88e-1)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.29e-1)" "unprognostic (5.23e-2)" "unprognostic (1.83e-2)" 8.0 4.1 21.6 4.4 24.3 31.4 9.9 22.0 33.6 3.5 17.8 22.6 9.6 2.2 3.1 4.8 6.1 8.1 4.0 24.2 20.5 5.8 1.0 3.8 2.7 22.5 23.0 4.6 8.0 11.3 4.0 7.6 22.0 6.5 21.7 20.8 3.2 5.0 8.4 5.9 11.7 3.4 22.5 4.3 13.2 5.9 24.4 4.1 5.2 3.4 2.5 2.8 2.7 32.9 10.6 22.2 21.8 12.9 12.0 14.2 13.9 177.1 50.1 21.4 19.5 1.4 23.2 0.1 17.1 108.5 12.6 12.2 12.6 15.1 33.5 30.1 20.6 18.0 28.3 7.1 6.1 9.1 11.4 10.9 19.5 8.7 17.1 38.3 12.8 13.2 9.1 24.2 24.8 13.5 5.2 13.2 14.9 5.7 13.6 26.4 14.5 38.7 9.2 10.1 23.0 21.2 6.3 11.7 45.2 15.4 24.3 10.3 33.6 115.6 9.5 24.8 29.9 13.6 22.6 19.6 14.5 5.1 45.7 37.6 3.6 6.2 3.4 3.2 2.9 4.1 2.8 3.6 3.5 2.0 2.5 2.4 3.2 7.3 3.7 2.0 7.3 3.0 21.6 24.3 22.0 33.6 24.2 20.5 22.5 23.0 22.0 22.5 24.4 32.9 2.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 103.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 21.5 0.5 0.0 0.0 0.0 MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102874982 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.7;lymphoid tissue: 40.4;urinary bladder: 16.0" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 303.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BJ: 3.3;fHDF/TERT166: 11.4;hTEC/SVTERT24-B: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" 0.5 0.0 0.0 40.4 0.1 0.0 0.4 0.0 0.0 0.1 0.0 13.5 6.8 0.6 0.0 0.4 0.0 2.6 0.0 0.0 0.3 0.9 0.1 0.6 7.0 0.1 0.1 0.0 0.1 0.0 0.0 7.4 0.1 1.3 15.7 0.0 2.4 0.0 0.0 0.5 7.8 2.2 0.1 3.7 3.5 0.0 0.1 3.9 0.0 0.0 19.4 16.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 11.4 0.1 0.4 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 18.6 303.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.0 2.2 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.0;Pancreatic endocrine cells: 144.7;Syncytiotrophoblasts: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 923.8;HHSteC: 794.2;HSkMC: 887.0;hTERT-RPE1: 925.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 151.5 31.7 5.6 59.9 5.0 1.6 101.5 5.7 7.5 181.3 61.8 77.2 39.5 167.3 19.0 92.1 82.1 148.2 41.3 6.6 7.2 35.9 13.2 91.8 24.8 11.9 8.4 90.2 36.0 65.3 14.2 118.9 9.2 59.9 36.6 9.6 78.1 45.5 18.8 127.5 69.4 106.0 7.3 30.8 57.7 11.7 13.2 13.0 50.0 16.1 30.8 103.9 111.1 10.6 90.6 1.2 26.3 2.0 923.8 651.6 455.9 270.1 606.4 93.3 158.5 21.3 337.4 0.9 146.4 301.9 24.6 216.3 0.3 262.2 99.7 1.1 0.6 37.2 1.7 5.0 794.2 0.4 1.3 887.0 148.7 334.7 288.3 925.5 492.9 0.6 0.8 2.1 185.1 0.7 0.4 79.4 14.7 17.7 52.4 2.1 96.0 0.2 61.4 148.1 0.3 0.6 187.3 0.3 574.2 104.4 1.0 79.5 436.8 724.9 53.7 198.2 329.6 0.8 1.6 1.1 410.9 0.6 396.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 5.0 5.7 7.5 6.6 7.2 11.9 8.4 9.2 7.3 13.2 10.6 13.9 12.8 3.0 2.0 3.4 34.0 23.4 105.4 39.3 0.0 14.1 17.5 4.7 50.1 42.2 7.3 0.0 105.6 0.3 19.9 11.7 63.0 0.4 16.1 81.6 35.2 7.8 0.0 0.0 28.7 244.0 84.0 25.5 14.8 3.8 9.3 32.9 2.7 89.5 0.0 0.0 24.5 34.6 20.2 32.7 2.4 72.1 38.0 37.4 4.7 21.5 14.3 0.0 0.5 0.1 144.7 33.0 54.9 0.3 21.8 19.9 11.7 46.8 0.8 39.5 11.1 73.9 0.8 0.8 33.7 34.2 122.7 2.5 15.6 18.6 37.9 MORF4L2 "KIAA0026, MRGX" ENSG00000123562 "Mortality factor 4 like 2" Q15014 X 103675496-103688158 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1214.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031872, HPA054102" Supported Enhanced Nucleoplasm NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA031872: AB_2674081, HPA054102: AB_2682379" "prognostic unfavorable (9.83e-4)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (7.14e-3)" "unprognostic (2.59e-1)" "prognostic unfavorable (4.29e-5)" "unprognostic (5.27e-2)" "unprognostic (6.34e-3)" "unprognostic (2.41e-1)" "unprognostic (4.49e-3)" "unprognostic (1.88e-1)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.86e-7)" "unprognostic (8.54e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-1)" 142.9 184.7 173.9 97.3 180.9 99.0 179.3 156.9 261.5 249.3 183.1 113.4 89.5 262.5 217.7 121.1 209.8 129.2 138.4 180.9 210.1 130.2 204.9 132.6 72.5 170.8 180.3 358.2 137.2 137.2 198.8 242.6 191.2 161.9 140.1 94.1 121.2 191.6 175.6 103.9 99.6 328.5 166.9 90.6 118.0 90.1 183.6 79.3 159.2 130.7 109.6 172.1 143.1 179.1 404.7 257.2 372.6 167.3 541.7 388.2 486.6 533.0 479.4 437.1 462.2 259.6 369.5 289.1 401.4 533.5 522.0 272.0 477.1 406.9 535.6 120.9 219.0 157.5 413.9 308.9 602.7 212.2 141.6 449.6 351.2 380.8 489.6 389.2 478.9 142.2 249.5 383.0 551.5 403.7 188.0 207.6 355.5 512.0 322.3 186.9 340.9 292.1 456.5 221.4 347.3 275.5 425.7 310.1 418.5 385.2 203.3 198.1 433.8 263.2 171.2 459.1 289.3 179.3 221.3 241.2 472.1 420.1 403.8 54.1 40.9 32.9 41.2 44.0 46.9 37.0 38.9 38.2 41.8 32.3 41.7 37.0 16.1 46.0 47.3 70.2 36.1 40.3 173.9 180.9 156.9 261.5 180.9 210.1 170.8 180.3 191.2 166.9 183.6 179.1 102.5 125.0 160.1 39.8 75.8 363.5 572.5 292.0 75.1 46.9 198.6 103.6 130.1 123.0 242.0 110.3 10.4 443.3 106.2 103.2 246.5 269.1 46.9 231.7 235.5 146.6 178.6 68.5 109.6 129.9 1214.1 266.0 90.7 187.2 155.8 153.5 118.5 196.8 163.6 58.9 104.4 202.0 219.7 61.7 254.9 34.2 330.9 90.8 188.5 32.8 68.7 117.0 40.2 59.3 78.2 176.8 118.9 574.8 120.9 332.7 105.1 282.9 429.7 38.8 144.7 164.9 287.9 37.2 48.0 112.7 317.8 583.5 118.2 171.5 134.4 396.8 MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865679-151101887 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Extravillous trophoblasts: 166.5;Granulosa cells: 86.9;Microglial cells: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;T-cells: 1.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Enhanced Mitochondria NA NA 89000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: AB_2680998, HPA074911: AB_2686723" "unprognostic (3.66e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (3.25e-1)" "prognostic unfavorable (5.10e-4)" "prognostic unfavorable (8.33e-5)" "unprognostic (6.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "unprognostic (2.93e-2)" "unprognostic (3.51e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (8.69e-5)" 12.5 12.2 7.1 11.4 6.7 13.2 7.9 25.1 7.4 7.1 8.3 7.4 3.2 8.4 6.2 6.7 7.1 5.9 11.5 6.4 9.8 12.7 5.6 19.5 11.1 11.5 10.1 14.6 10.7 6.8 9.2 14.3 11.0 5.5 7.9 7.5 3.2 7.0 1.3 6.0 5.2 10.0 11.6 9.2 6.0 9.9 8.4 8.6 10.9 0.5 10.8 12.8 4.2 15.4 40.6 35.1 44.9 110.0 11.5 40.0 108.4 63.0 68.3 62.1 75.7 71.8 37.4 152.3 41.1 96.9 36.8 42.7 72.4 61.8 76.8 63.4 65.3 62.7 60.4 66.1 72.4 115.7 9.8 47.7 76.9 60.6 109.8 55.5 105.5 81.6 150.9 76.2 65.0 86.1 57.1 23.9 45.5 40.7 32.1 67.2 33.2 67.1 42.1 19.6 44.1 32.5 83.9 36.7 53.0 40.6 11.5 79.5 80.6 41.4 90.6 91.9 90.5 62.3 63.5 154.0 68.8 105.7 54.0 0.0 0.2 0.0 0.2 0.3 0.4 0.2 0.6 0.7 1.1 0.3 0.5 0.6 0.0 0.3 0.3 0.5 1.8 0.2 7.1 6.7 25.1 7.4 6.4 9.8 11.5 10.1 11.0 11.6 8.4 15.4 6.9 0.0 1.7 47.7 6.9 6.5 8.0 15.7 1.8 0.0 3.3 4.1 2.4 1.5 9.8 14.7 0.0 25.8 1.4 2.6 7.9 9.0 44.9 11.3 18.4 10.7 1.2 5.0 84.0 18.1 166.5 14.4 8.2 22.2 0.0 86.9 6.1 1.7 24.9 0.0 73.8 3.0 46.8 3.0 13.3 6.2 0.6 13.8 35.6 126.5 2.4 0.0 2.1 60.8 59.3 19.2 1.4 7.9 14.0 31.3 0.9 15.2 5.3 0.0 0.0 8.7 13.1 0.5 6.8 2.3 3.4 73.6 4.0 42.9 4.0 35.1 MTSS2 "ABBA, ABBA-1, LOC92154, MTSS1L" ENSG00000132613 "MTSS I-BAR domain containing 2" Q765P7 16 70661204-70686053 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 372.5" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 48.0" "Cancer enhanced" "Detected in all" "glioma: 26.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 299.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048531, HPA066469" Approved Supported "Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "Focal adhesion sites" "HPA048531: AB_2680430, HPA066469: AB_2685671" "prognostic unfavorable (2.85e-4)" "unprognostic (8.85e-2)" "unprognostic (7.01e-2)" "unprognostic (5.99e-2)" "unprognostic (3.21e-1)" "unprognostic (2.98e-1)" "unprognostic (1.86e-1)" "unprognostic (1.82e-1)" "unprognostic (5.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.59e-3)" "unprognostic (3.88e-1)" "unprognostic (2.92e-3)" "unprognostic (9.87e-2)" "unprognostic (9.92e-2)" "unprognostic (6.74e-2)" "unprognostic (2.25e-2)" 31.7 40.5 299.2 20.9 295.8 9.4 26.9 283.7 279.1 66.1 102.2 89.2 14.3 78.9 6.1 50.7 47.4 29.0 36.7 296.0 324.9 25.3 106.0 47.2 10.1 372.5 316.2 35.6 13.7 12.8 25.0 36.0 311.5 42.1 8.2 25.6 30.6 37.1 81.1 32.6 27.4 60.0 254.5 58.3 29.9 10.8 313.2 42.5 21.3 29.9 7.9 46.6 46.0 278.5 67.2 157.4 38.9 40.4 31.6 31.2 146.4 98.8 122.0 83.0 68.5 63.8 41.9 0.8 34.6 155.5 33.0 136.9 42.5 43.2 31.5 1.2 56.9 23.2 137.7 299.9 278.1 35.0 1.1 129.3 92.6 38.6 133.0 35.7 27.6 35.0 88.8 1.4 74.8 164.1 33.4 177.8 34.2 22.6 33.1 70.6 72.5 0.4 72.4 99.0 91.1 61.0 210.5 90.6 27.2 36.6 69.9 67.2 41.9 64.3 72.6 59.0 62.7 23.4 6.4 1.2 58.3 1.0 22.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 299.2 295.8 283.7 279.1 296.0 324.9 372.5 316.2 311.5 254.5 313.2 278.5 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 48.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 MYCN "bHLHe37, MYCNOT, N-myc, NMYC" ENSG00000134323 "MYCN proto-oncogene, bHLH transcription factor" P04198 2 15940550-15947007 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 9.5" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 84.2;Granulosa cells: 26.4" "Cancer enriched" "Detected in many" 5 "testis cancer: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057420 Approved Nucleoplasm,Nucleoli NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA057420: AB_2683434" "unprognostic (8.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-2)" "unprognostic (4.11e-1)" "unprognostic (2.46e-2)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" "unprognostic (1.12e-3)" "unprognostic (8.89e-2)" "unprognostic (2.47e-1)" "unprognostic (4.90e-2)" "unprognostic (1.23e-1)" 0.4 0.8 3.5 0.6 3.5 0.9 0.4 3.1 3.9 1.5 0.8 0.6 1.6 0.9 0.1 0.7 0.5 0.3 1.2 3.4 3.0 3.3 0.8 0.7 1.6 4.4 3.9 5.1 0.2 0.1 0.3 9.5 3.7 0.1 0.5 1.0 4.7 0.2 0.4 1.4 0.9 0.3 3.3 0.3 4.6 3.6 3.5 2.9 2.9 0.7 1.2 0.5 0.4 5.9 0.0 0.0 44.1 0.0 0.0 0.0 239.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 4.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.8 0.4 0.2 91.3 2.1 0.0 0.0 63.3 12.8 0.0 3.1 1.0 16.0 0.0 0.1 0.0 40.9 0.1 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.5 3.1 3.9 3.4 3.0 4.4 3.9 3.7 3.3 3.5 5.9 0.8 0.0 0.0 0.7 0.0 0.5 0.1 0.0 0.0 2.6 0.1 0.9 0.7 0.0 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 1.2 0.5 0.1 2.7 0.0 4.2 2.0 0.0 84.2 1.0 2.6 0.8 0.0 26.4 0.0 0.6 2.4 0.0 4.2 0.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.1 1.0 0.0 10.1 7.5 0.3 1.1 0.4 0.0 0.0 0.4 3.2 0.0 0.2 0.0 4.2 0.7 1.3 3.7 0.3 0.0 11.5 0.0 9.4 0.3 0.0 N4BP3 LZTS4 ENSG00000145911 "NEDD4 binding protein 3" O15049 5 178113532-178126081 "Predicted intracellular proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 35.7;Extravillous trophoblasts: 130.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 1.7;naive B-cell: 1.6;naive CD8 T-cell: 1.2;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 16 "B-cells: 1.7;dendritic cells: 2.1;T-cells: 1.2" "Cell line enhanced" "Detected in many" "BEWO: 14.9;MCF7: 21.2;RH-30: 20.3;SK-BR-3: 72.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030972, HPA030973, HPA061387" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Centrosome "HPA030972: AB_2673680, HPA030973: AB_10603574, HPA061387: " "unprognostic (1.84e-1)" "unprognostic (1.70e-2)" "unprognostic (4.96e-3)" "unprognostic (6.64e-3)" "unprognostic (2.06e-1)" "unprognostic (3.18e-3)" "unprognostic (1.88e-6)" "unprognostic (1.45e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (3.28e-3)" "unprognostic (9.55e-2)" "prognostic favorable (2.38e-4)" "unprognostic (2.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 1.9 0.8 1.6 1.0 1.0 2.9 2.5 3.0 3.7 2.6 0.6 1.4 0.5 0.8 0.3 15.7 1.0 0.7 2.3 1.0 2.1 3.1 0.1 3.9 1.8 2.6 1.8 0.5 0.7 4.1 2.2 8.3 2.7 1.0 0.4 4.7 6.8 0.8 4.4 7.8 1.8 0.5 0.2 1.8 2.2 0.9 4.1 0.9 1.4 3.0 2.9 1.4 4.0 2.1 0.1 0.1 2.3 1.7 0.2 0.0 14.9 0.0 0.0 0.0 0.0 3.3 1.1 1.4 2.0 0.0 0.1 4.7 0.4 0.1 0.0 2.5 0.8 4.1 1.8 0.1 0.1 0.2 0.0 0.3 0.5 0.0 0.1 0.0 12.0 1.3 2.6 0.9 0.0 21.2 0.2 0.3 11.2 3.6 0.1 11.6 20.3 5.4 1.2 2.4 1.7 0.8 0.6 72.2 4.9 2.8 2.8 0.1 2.4 0.0 1.7 0.0 0.0 3.2 2.3 13.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 1.7 0.1 0.1 0.0 1.6 0.4 1.2 0.0 0.1 0.0 2.1 0.0 0.2 1.6 1.0 3.0 3.7 1.0 2.1 2.6 1.8 2.7 0.2 4.1 2.1 7.8 3.2 0.6 0.0 12.7 9.4 13.1 6.7 4.0 35.7 7.3 3.6 1.7 2.8 3.4 1.8 12.5 3.0 10.4 9.4 13.7 3.4 0.4 1.9 1.1 15.7 4.2 0.0 2.9 0.8 130.4 1.6 6.6 5.8 4.5 0.5 0.4 0.2 2.3 1.7 4.9 3.7 6.1 0.0 1.7 0.8 0.6 1.0 12.4 3.7 1.1 2.0 0.0 0.5 0.2 7.3 8.7 1.9 6.1 10.3 0.1 0.8 0.3 9.2 0.0 2.5 0.7 0.2 8.1 14.1 6.8 23.1 3.0 0.7 3.5 12.1 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 121.0;Hofbauer cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: AB_2150651, HPA056828: AB_2683250" "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 18.0 6.1 33.5 32.6 34.3 19.6 14.7 28.1 32.4 26.1 26.5 22.3 17.5 12.2 3.4 8.5 11.2 25.4 7.4 31.8 37.0 17.2 68.2 24.3 27.4 49.8 41.2 9.0 16.7 1.9 6.1 30.2 33.9 19.6 22.5 11.3 20.6 16.7 8.2 5.4 25.8 18.7 34.4 16.6 27.1 7.8 44.2 10.2 7.3 3.1 31.7 24.3 6.4 30.4 31.8 50.0 47.8 18.8 88.3 113.9 59.3 38.8 61.1 58.4 48.4 47.7 57.0 38.2 61.0 74.6 133.2 5.9 24.7 111.7 39.4 43.7 21.8 104.4 42.1 85.4 105.2 19.4 250.0 152.8 17.8 55.4 56.9 152.3 64.3 17.6 19.5 1.7 105.6 32.6 0.9 20.8 12.2 163.7 45.5 40.6 35.6 19.6 62.6 11.4 21.4 7.5 12.6 23.6 54.5 48.3 51.4 76.4 127.5 42.2 42.8 29.5 26.7 8.4 11.4 21.6 53.5 42.3 57.5 28.1 47.6 76.4 9.2 32.1 5.9 52.5 5.5 7.8 29.0 30.2 0.9 3.8 58.8 23.3 41.4 26.9 7.6 21.6 33.5 34.3 28.1 32.4 31.8 37.0 49.8 41.2 33.9 34.4 44.2 30.4 8.4 9.6 4.7 37.9 24.5 2.4 13.8 18.9 4.6 1.0 9.4 6.5 3.3 18.6 8.8 3.7 0.0 47.1 11.3 8.5 1.9 41.3 18.2 9.4 17.7 8.4 6.0 4.0 8.3 23.3 121.0 11.1 19.4 22.2 22.2 1.1 5.0 43.5 112.0 0.0 5.3 18.2 18.3 10.4 22.5 20.0 5.0 31.2 7.2 12.2 57.7 34.6 8.2 15.1 2.4 30.6 11.9 3.8 5.5 17.1 17.2 38.0 3.3 2.1 0.0 4.9 6.4 1.3 17.1 2.4 1.1 36.1 4.5 2.1 18.7 10.2 NKAP FLJ22626 ENSG00000101882 "NFKB activating protein" Q8N5F7 X 119920672-119943751 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Repressor "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000916 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA000916: AB_1079486" "prognostic unfavorable (4.20e-4)" "unprognostic (4.28e-3)" "unprognostic (9.14e-2)" "unprognostic (1.33e-3)" "unprognostic (2.66e-1)" "unprognostic (3.42e-2)" "unprognostic (3.49e-3)" "unprognostic (4.18e-3)" "unprognostic (3.70e-2)" "unprognostic (1.05e-2)" "unprognostic (1.05e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-3)" "unprognostic (1.72e-1)" "unprognostic (1.53e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" 9.5 13.1 10.6 9.8 11.5 13.6 10.6 11.8 16.2 9.2 11.1 9.8 10.3 10.6 10.7 7.3 11.0 8.9 11.0 10.5 11.6 11.3 14.5 10.5 14.4 11.9 11.5 14.1 10.1 14.2 2.7 13.5 11.4 10.4 10.1 9.6 9.9 13.5 18.2 7.4 12.7 10.3 11.2 12.5 9.3 8.5 11.0 12.7 10.1 14.4 13.0 9.7 2.4 13.0 25.0 24.3 17.6 22.3 15.3 24.7 28.9 17.7 20.4 23.4 17.2 15.9 20.9 17.6 29.9 14.6 45.8 18.3 33.7 20.6 27.9 29.6 31.2 11.1 20.6 23.3 25.1 25.2 20.4 17.9 26.4 25.1 24.7 25.3 23.2 23.8 30.6 25.5 18.4 33.8 21.4 47.0 23.6 32.4 32.8 22.8 24.3 32.7 17.5 9.6 19.2 27.2 36.8 19.7 52.3 20.9 16.8 21.1 17.4 14.8 9.0 38.4 27.4 25.4 26.7 30.2 20.4 18.9 26.1 39.7 23.5 55.6 20.8 20.0 21.6 32.2 25.4 21.2 20.6 36.6 25.6 24.3 44.5 22.2 23.1 32.5 26.6 14.3 10.6 11.5 11.8 16.2 10.5 11.6 11.9 11.5 11.4 11.2 11.0 13.0 39.9 22.4 40.4 5.2 36.1 25.9 36.1 45.5 26.7 34.0 26.2 33.3 30.3 15.7 42.3 20.2 25.0 62.5 36.0 17.5 37.2 36.7 8.8 33.6 37.4 40.3 22.8 20.6 7.2 44.3 132.0 39.1 17.9 26.7 47.4 41.6 41.4 46.3 53.0 55.5 9.0 27.9 22.4 28.0 23.2 8.9 45.1 33.9 35.6 4.7 35.3 56.3 36.0 7.5 11.0 37.5 23.3 55.3 30.6 40.3 25.8 51.3 49.4 38.5 13.1 33.4 45.0 82.7 69.6 19.6 28.7 72.9 41.5 48.3 23.1 33.7 NLRP2 "CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2" ENSG00000022556 "NLR family pyrin domain containing 2" Q9NX02 19 54953130-55001142 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.2;Extravillous trophoblasts: 216.1;Syncytiotrophoblasts: 97.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 78.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 42.2;BEWO: 177.9;OE19: 79.7;SuSa: 80.3;T-47d: 46.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021183 Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "HPA021183: AB_2670615" "unprognostic (1.66e-2)" "unprognostic (9.28e-2)" "unprognostic (6.60e-2)" "unprognostic (6.50e-3)" "unprognostic (1.09e-2)" "unprognostic (4.57e-3)" "unprognostic (4.27e-1)" "unprognostic (1.79e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.63e-1)" "unprognostic (2.34e-2)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (8.86e-2)" "unprognostic (7.57e-2)" 0.4 0.3 0.9 2.7 0.6 1.0 1.0 0.0 0.8 2.6 0.1 1.7 1.8 1.1 1.8 7.9 1.9 0.9 0.4 0.7 0.1 1.9 0.4 1.6 2.1 0.1 0.2 0.3 1.6 0.4 1.2 7.1 0.1 1.5 1.9 3.1 2.4 1.1 0.6 3.0 1.7 0.8 0.0 2.1 2.5 7.2 0.3 3.4 4.4 0.0 1.9 7.1 4.3 0.2 20.4 42.2 15.8 0.4 0.2 0.1 177.9 0.1 0.0 0.6 0.2 35.9 0.7 14.7 0.1 0.1 0.1 8.1 0.0 24.4 0.3 1.7 0.2 9.8 0.5 0.1 0.4 0.1 0.4 0.2 0.3 0.0 0.1 0.1 0.9 0.0 32.7 0.2 0.0 0.3 0.1 1.3 5.0 79.7 0.0 8.8 0.0 24.0 26.4 0.7 5.3 0.7 0.0 8.1 0.0 80.3 46.7 0.2 0.0 0.3 0.7 0.4 0.3 5.2 16.6 0.7 0.4 1.0 0.0 0.1 0.2 0.0 1.8 0.3 1.3 0.6 0.4 0.7 0.2 0.6 0.3 0.8 0.2 3.0 0.1 1.0 1.3 0.4 0.9 0.6 0.0 0.8 0.7 0.1 0.1 0.2 0.1 0.0 0.3 0.2 0.0 9.6 7.3 0.3 1.5 0.5 1.9 8.1 0.0 2.7 1.9 1.5 0.8 4.3 10.1 1.8 4.2 45.2 3.5 2.9 0.0 5.3 23.1 8.6 1.3 0.7 2.4 0.8 3.0 1.9 216.1 1.1 2.0 13.1 4.5 0.7 0.0 0.0 11.6 0.0 1.9 3.0 6.1 0.3 0.5 7.2 0.9 1.1 0.0 0.0 3.0 0.7 8.2 0.5 0.5 6.7 1.0 0.0 1.5 2.5 0.8 0.4 8.4 2.7 0.0 0.3 0.8 16.8 11.7 0.0 1.3 97.3 2.4 0.3 3.0 4.7 NLRP9 "CLR19.1, NALP9, NOD6, PAN12" ENSG00000185792 "NLR family pyrin domain containing 9" Q7RTR0 19 55708438-55738402 "Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 40 "Extravillous trophoblasts: 61.2" "Cancer enriched" "Detected in single" 59 "testis cancer: 14.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042623 Uncertain NA NA "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA042623: AB_10965692" "unprognostic (2.50e-1)" "unprognostic (3.03e-1)" "unprognostic (1.74e-1)" "unprognostic (2.85e-1)" "unprognostic (8.82e-2)" "unprognostic (6.53e-2)" "unprognostic (9.92e-3)" "unprognostic (1.63e-1)" "unprognostic (9.55e-2)" "unprognostic (3.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.40e-1)" "unprognostic (4.56e-3)" "unprognostic (2.73e-1)" "unprognostic (3.46e-1)" "unprognostic (9.56e-2)" "unprognostic (8.09e-3)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 61.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 135.7" "Cell type enriched" "Detected in some" 45 "Extravillous trophoblasts: 1002.5" "Cancer enhanced" "Detected in many" "stomach cancer: 48.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 428.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" NA NA 1900000 "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" 0.0 0.1 1.6 0.0 1.9 0.0 0.2 0.6 1.8 0.2 0.1 0.0 1.1 2.1 0.3 0.3 0.4 0.2 0.3 1.0 1.0 1.2 10.0 2.2 0.0 1.7 2.7 0.1 0.4 0.9 0.2 135.7 1.3 0.3 0.0 0.0 0.6 0.1 8.2 2.2 0.3 0.1 0.9 0.2 2.1 2.8 1.3 0.0 0.0 0.5 0.0 1.4 0.2 0.8 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 10.0 0.4 0.0 1.8 0.3 0.2 0.4 2.4 0.0 0.0 0.1 1.1 2.2 2.8 428.6 0.2 0.4 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.2 11.2 0.0 0.0 0.6 0.0 0.2 0.1 67.9 0.4 0.0 0.2 0.1 0.0 0.2 15.7 1.6 4.2 1.7 6.2 2.3 0.1 4.9 0.0 0.5 6.3 0.0 0.2 0.1 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 0.6 1.8 1.0 1.0 1.7 2.7 1.3 0.9 1.3 0.8 0.0 0.0 3.7 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.6 1.3 1.2 0.0 0.0 0.0 0.0 10.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.8 0.0 0.0 0.6 0.0 1002.5 1.2 1.5 0.3 0.0 0.1 0.0 3.6 18.4 0.0 1.1 0.1 0.0 0.0 0.3 0.2 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.5 12.7 0.0 0.0 22.0 0.1 0.0 0.3 0.0 NR6A1 "CT150, GCNF, GCNF1, RTR" ENSG00000148200 "Nuclear receptor subfamily 6 group A member 1" Q15406 9 124517275-124771311 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.5;Extravillous trophoblasts: 160.0;Inhibitory neurons: 114.7;Oligodendrocyte precursor cells: 112.6;Spermatogonia: 111.1" "Cancer enriched" "Detected in many" 16 "testis cancer: 27.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.2;neutrophil: 4.9" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.9" "Cell line enhanced" "Detected in many" "BEWO: 110.7;CACO-2: 26.5;Hep G2: 25.8;K-562: 34.1;NTERA-2: 39.2;U-266/84: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031461, HPA045145" Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Centrosome, Cytosol" "HPA031461: AB_2673894, HPA045145: AB_2679233" "unprognostic (1.73e-1)" "unprognostic (6.66e-2)" "unprognostic (4.53e-1)" "unprognostic (1.34e-6)" "unprognostic (4.40e-2)" "unprognostic (3.20e-2)" "unprognostic (2.52e-5)" "unprognostic (6.31e-2)" "unprognostic (8.01e-3)" "unprognostic (2.71e-2)" "unprognostic (1.58e-2)" "unprognostic (1.63e-1)" "unprognostic (7.26e-2)" "unprognostic (7.20e-3)" "unprognostic (1.71e-1)" "unprognostic (6.77e-3)" "unprognostic (1.09e-1)" 0.3 0.8 1.8 0.9 1.9 4.4 0.9 2.2 1.9 0.8 4.5 2.2 1.7 0.5 0.5 1.9 0.5 0.4 1.0 1.8 1.5 1.7 2.7 1.5 0.3 2.0 1.5 0.3 2.9 0.8 1.4 2.3 1.5 1.4 1.5 3.1 1.2 0.5 1.4 2.2 2.5 0.4 1.4 0.8 0.4 22.9 3.4 0.1 5.4 0.8 0.7 0.7 1.3 1.6 1.2 3.0 14.7 2.0 0.3 0.2 110.7 0.2 1.1 0.8 1.3 26.5 2.9 5.0 1.0 0.1 3.8 2.8 1.6 1.3 1.7 1.1 4.6 4.1 4.8 25.8 0.1 2.3 7.2 0.1 1.3 1.2 1.6 0.3 0.2 1.2 34.1 0.7 0.6 0.6 0.1 3.2 39.2 1.3 1.1 1.2 1.5 2.2 0.5 2.0 2.2 0.8 0.2 0.7 0.9 21.7 2.6 1.3 0.0 1.4 3.1 0.9 0.7 3.3 25.0 4.3 0.9 2.3 0.8 0.0 0.6 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 4.9 0.0 0.3 0.1 0.0 0.1 1.8 1.9 2.2 1.9 1.8 1.5 2.0 1.5 1.5 1.4 3.4 1.6 0.8 0.0 7.7 47.0 0.6 37.3 17.4 4.2 13.6 3.8 6.8 3.7 2.0 7.2 5.9 5.5 29.2 36.7 1.6 8.9 1.9 10.1 53.5 4.1 0.9 3.2 4.8 6.1 105.5 3.5 160.0 2.0 2.0 3.7 1.3 16.1 1.4 6.0 8.2 1.7 114.7 6.9 8.2 2.2 30.6 30.3 1.2 3.2 8.8 54.4 5.2 7.0 0.0 112.6 73.0 1.9 6.0 1.9 0.5 19.4 24.5 3.3 8.6 10.7 0.0 1.5 3.5 72.7 111.1 8.6 39.8 30.6 0.3 8.1 11.9 15.5 NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037726-48047221 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038968, HPA038969" Approved Supported Nucleoplasm Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA038968: AB_10697402, HPA038969: AB_2676295" "unprognostic (9.48e-2)" "unprognostic (5.91e-3)" "unprognostic (2.64e-2)" "unprognostic (9.00e-3)" "unprognostic (4.99e-2)" "unprognostic (2.50e-3)" "unprognostic (2.29e-2)" "unprognostic (7.47e-3)" "prognostic unfavorable (1.25e-5)" "unprognostic (1.04e-1)" "unprognostic (8.50e-2)" "unprognostic (3.69e-1)" "unprognostic (4.63e-2)" "unprognostic (1.84e-3)" "unprognostic (3.35e-1)" "unprognostic (9.58e-2)" "unprognostic (8.93e-3)" 12.2 13.0 7.1 10.1 7.2 18.0 16.4 8.6 8.3 12.9 6.9 20.2 20.8 9.7 13.8 16.3 11.6 9.0 11.0 6.9 8.5 17.2 14.1 9.2 7.5 7.2 7.7 8.6 9.4 8.2 9.4 12.6 7.8 15.1 22.1 10.3 12.1 10.0 11.9 8.7 16.3 10.5 6.8 5.5 13.0 10.7 7.6 10.7 13.4 18.7 10.3 12.9 10.3 7.8 47.5 28.4 52.4 23.1 21.2 30.3 37.8 37.7 35.8 41.3 39.7 42.1 45.2 34.6 20.7 30.3 36.7 54.3 51.3 56.1 63.4 18.3 41.8 34.1 28.0 46.2 19.8 52.0 31.2 20.9 35.3 33.3 46.7 18.4 45.3 34.5 30.7 13.5 67.2 23.2 40.5 48.4 83.0 72.8 32.2 27.6 33.8 22.7 46.2 35.8 31.4 33.1 25.6 43.8 30.3 44.7 22.5 38.7 23.0 28.5 34.7 36.2 53.3 6.9 12.5 43.6 14.8 40.1 47.4 1.6 4.8 3.5 2.9 6.9 2.9 3.1 4.6 3.6 4.9 2.6 5.3 5.8 1.0 2.8 4.8 3.7 3.4 2.7 7.1 7.2 8.6 8.3 6.9 8.5 7.2 7.7 7.8 6.8 7.6 7.8 12.0 12.8 15.7 0.7 14.7 16.6 34.6 18.1 19.9 9.2 14.0 11.6 12.5 12.8 20.7 7.3 2.1 36.2 12.6 30.4 49.0 17.3 16.7 45.7 20.4 15.1 8.4 10.5 3.9 17.6 79.4 12.8 18.3 39.5 9.5 8.7 7.5 17.4 16.8 38.7 3.1 23.5 26.4 7.8 10.5 9.3 16.8 11.4 10.6 1.9 10.3 10.8 6.2 0.5 3.0 16.4 18.3 12.4 16.8 41.9 18.9 40.8 13.6 9.0 0.0 9.5 17.1 8.9 34.4 34.9 20.5 38.0 13.2 15.3 31.9 42.0 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "Extravillous trophoblasts: 49.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cell line enhanced" "Detected in some" "RT4: 3.3;SK-BR-3: 1.4;U-2 OS: 1.6" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 1.3 0.0 1.0 1.3 0.8 0.1 4.2 0.5 1.5 1.0 0.5 2.0 0.2 0.5 2.5 2.1 1.6 0.1 0.2 0.8 2.1 4.0 0.0 0.4 0.1 1.2 1.3 0.1 0.5 0.3 0.3 0.9 1.0 0.5 1.6 0.0 3.0 0.4 0.2 2.6 0.4 0.5 0.7 0.4 0.2 0.1 2.6 0.3 0.5 0.3 0.8 1.7 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.1 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 1.0 0.8 0.5 1.5 0.8 2.1 1.2 1.3 1.0 0.7 2.6 1.3 0.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 1.7 1.4 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.2 1.9 0.0 0.2 0.7 0.1 0.8 1.2 0.0 0.6 0.0 49.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.5 0.0 0.0 0.4 0.1 0.0 0.3 3.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.9 0.0 0.0 2.2 0.0 3.7 0.0 0.0 1.2 0.0 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PEDS1 "CarF, Kua, TMEM189" ENSG00000240849 "Plasmanylethanolamine desaturase 1" A5PLL7 20 50118254-50153734 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 86.8;Extravillous trophoblasts: 167.6;Hofbauer cells: 38.6;Syncytiotrophoblasts: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059549 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA059549: AB_2684059" "unprognostic (3.11e-2)" "unprognostic (7.04e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (2.03e-3)" "unprognostic (7.00e-2)" "unprognostic (2.19e-2)" "unprognostic (1.35e-1)" "unprognostic (8.63e-2)" "unprognostic (5.79e-2)" "prognostic unfavorable (5.79e-11)" "unprognostic (1.85e-1)" "unprognostic (1.20e-1)" "unprognostic (9.46e-2)" "unprognostic (4.42e-2)" 13.2 14.0 19.6 7.3 24.0 5.7 10.4 25.3 24.3 12.7 15.8 18.4 8.7 13.8 10.7 26.0 9.1 7.2 20.8 19.6 20.8 9.3 17.8 13.7 6.0 25.8 24.4 5.5 9.3 12.8 5.8 17.6 24.1 11.6 7.1 2.2 12.4 13.5 16.9 22.9 9.8 21.8 21.0 10.0 15.1 6.3 23.3 7.8 7.7 16.3 7.4 15.4 15.1 29.1 19.6 17.7 20.7 16.3 30.7 23.0 34.6 13.6 12.6 27.8 15.6 48.6 30.5 7.2 21.2 12.8 39.7 52.8 10.4 27.4 10.0 3.8 8.0 9.3 24.5 41.6 17.3 15.1 24.2 19.7 62.7 15.6 16.4 13.4 33.6 12.2 9.8 10.2 9.5 17.3 12.0 38.1 10.1 50.1 18.3 9.7 15.9 7.8 53.7 28.4 10.8 7.1 15.4 52.2 32.4 20.3 8.3 21.2 26.8 23.1 12.1 15.1 13.5 7.5 13.6 2.9 19.9 11.1 19.1 4.9 5.3 6.2 3.1 10.2 2.6 1.8 3.5 2.6 5.6 1.5 2.9 3.4 2.0 4.0 14.0 3.6 5.6 3.8 19.6 24.0 25.3 24.3 19.6 20.8 25.8 24.4 24.1 21.0 23.3 29.1 8.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 86.8 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 167.6 6.3 0.0 0.0 0.0 0.0 0.0 0.0 38.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 50.1 1.2 0.0 0.0 0.0 PEX19 "D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1" ENSG00000162735 "Peroxisomal biogenesis factor 19" P40855 1 160276807-160286348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044837, HPA051966" Supported Supported Peroxisomes NA NA 7900 "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Peroxisomes "HPA044837: AB_10962496, HPA051966: AB_2681677" "unprognostic (1.49e-2)" "unprognostic (2.26e-1)" "unprognostic (3.42e-1)" "unprognostic (4.80e-3)" "unprognostic (3.89e-2)" "unprognostic (3.88e-2)" "unprognostic (3.79e-1)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.53e-2)" "unprognostic (8.06e-2)" "unprognostic (1.00e-1)" "prognostic favorable (2.92e-5)" "unprognostic (3.46e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-2)" "unprognostic (1.24e-2)" 79.3 25.7 21.1 14.5 22.5 12.3 36.5 22.2 23.5 20.3 15.6 22.6 19.4 18.2 25.0 24.9 22.9 19.6 39.4 21.5 22.7 33.1 109.1 21.6 16.6 22.3 23.5 23.6 17.2 40.4 15.0 21.9 23.5 28.0 23.2 30.9 21.3 26.6 66.2 18.2 18.8 16.7 22.1 16.7 20.0 16.8 22.7 21.0 34.3 84.8 20.5 23.9 15.2 24.5 31.2 18.9 69.8 22.4 59.8 57.8 53.0 25.3 51.3 44.6 35.3 35.1 37.2 37.8 40.9 37.3 26.3 29.7 34.2 44.0 35.3 32.3 17.3 26.6 26.5 36.3 46.9 48.6 32.6 84.7 51.0 60.0 38.6 35.8 32.2 51.4 40.8 27.9 50.0 17.8 37.0 15.8 50.3 38.6 48.2 45.7 34.4 45.5 45.8 61.8 23.2 38.3 98.3 49.5 37.4 71.3 48.1 48.2 24.8 26.5 31.1 29.9 30.1 42.5 57.9 68.6 43.1 20.9 38.9 9.1 5.5 5.0 5.8 8.9 4.2 5.0 2.8 3.5 5.5 1.9 4.0 3.7 2.2 4.7 6.6 3.4 4.2 2.3 21.1 22.5 22.2 23.5 21.5 22.7 22.3 23.5 23.5 22.1 22.7 24.5 16.4 9.6 20.6 9.1 12.7 9.9 21.0 15.4 13.1 18.8 18.9 16.4 45.6 20.0 11.3 16.5 10.4 30.0 6.9 25.4 49.0 22.6 6.6 12.0 13.7 13.6 11.4 15.6 8.6 14.8 51.2 18.4 13.3 12.0 16.5 15.6 20.0 60.1 30.1 25.2 9.0 11.5 0.0 15.7 7.0 3.1 21.8 15.0 21.4 6.5 24.9 39.0 12.3 6.0 11.5 20.2 17.2 29.3 9.5 18.5 29.8 40.7 11.8 12.7 32.9 14.6 16.2 17.8 25.3 15.0 9.9 38.7 12.5 18.2 15.7 25.2 PFKFB4 ENSG00000114268 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" Q16877 3 48517684-48562015 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 40.3;Proximal enterocytes: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 12.5;eosinophil: 21.9;intermediate monocyte: 13.8;neutrophil: 40.4;non-classical monocyte: 25.1" "Group enriched" "Detected in many" 6 "granulocytes: 40.4;monocytes: 25.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 52.5;U-87 MG: 83.9;WM-115: 74.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047719, HPA066058" Uncertain Approved Nucleoli NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli "HPA047719: AB_2680129, HPA066058: AB_2685606" "unprognostic (7.60e-2)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (3.90e-3)" "unprognostic (7.96e-2)" "unprognostic (1.72e-6)" "unprognostic (1.65e-1)" "unprognostic (3.75e-2)" "unprognostic (6.78e-2)" "unprognostic (3.78e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.91e-8)" "unprognostic (2.04e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-3)" "unprognostic (3.35e-2)" 1.8 2.5 5.1 4.0 5.5 14.8 1.9 6.1 6.3 3.3 3.4 3.3 18.4 2.0 18.0 7.3 1.6 1.6 1.5 5.1 6.5 3.5 1.7 4.2 1.5 6.8 6.4 3.3 11.2 3.2 5.2 10.2 6.9 3.6 3.4 16.1 2.7 1.3 5.4 3.8 20.8 2.4 5.9 10.3 1.3 24.0 7.7 1.3 1.6 3.4 1.1 2.0 5.8 6.7 12.0 3.9 8.3 8.1 2.8 4.0 16.6 6.1 10.4 11.9 29.3 6.0 4.2 5.5 5.8 4.6 28.4 3.5 3.6 10.6 10.6 3.5 2.9 12.3 9.3 6.7 2.5 2.3 5.1 4.2 15.6 19.4 1.9 52.5 2.9 6.7 4.4 4.5 9.7 2.8 0.8 17.3 5.0 2.3 8.0 0.9 4.1 5.9 4.5 11.4 2.5 5.4 6.6 3.0 23.6 8.2 6.3 5.3 0.9 12.0 4.7 1.6 36.7 21.6 4.4 3.2 83.9 4.3 74.8 0.0 12.5 21.9 0.4 13.8 0.1 0.3 0.6 0.1 5.1 0.2 1.0 0.3 40.4 0.5 25.1 0.6 0.0 4.9 5.1 5.5 6.1 6.3 5.1 6.5 6.8 6.4 6.9 5.9 7.7 6.7 0.1 0.0 1.3 13.1 0.3 3.2 0.3 7.0 1.8 6.3 1.6 1.3 1.0 2.8 2.1 0.0 2.1 13.8 0.2 1.3 0.0 2.9 2.8 1.9 2.4 0.8 4.2 0.4 4.5 1.5 40.3 1.2 0.5 3.3 1.3 2.0 1.1 1.0 6.0 6.7 7.3 13.0 2.0 7.8 0.5 2.6 0.9 7.3 1.8 3.7 3.5 3.3 1.0 6.0 13.9 2.9 1.4 0.7 1.8 0.4 43.6 0.2 2.7 4.4 0.0 0.1 1.5 0.5 0.8 2.5 1.7 5.5 0.9 1.3 3.7 0.1 PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 50.5;thyroid gland: 52.5" "Group enriched" "Detected in many" 11 "Extravillous trophoblasts: 1604.4;Syncytiotrophoblasts: 2122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "BEWO: 422.4;HUVEC TERT2: 199.1" "Low region specificity" "Detected in all" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" No No 20800 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Mitochondria, Cytosol" "HPA041624: AB_10794522" "unprognostic (1.67e-2)" "unprognostic (4.62e-2)" "unprognostic (9.25e-3)" "unprognostic (1.34e-3)" "unprognostic (8.67e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (4.45e-1)" "unprognostic (1.45e-2)" "unprognostic (3.51e-3)" "prognostic unfavorable (1.33e-6)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (1.14e-1)" 11.8 4.9 7.4 7.8 7.6 0.1 11.3 7.3 11.7 22.4 20.2 7.0 2.4 7.6 1.4 10.0 21.8 5.9 18.8 8.7 20.6 8.1 6.0 7.2 6.4 9.5 15.7 6.4 4.9 8.4 5.5 50.5 9.3 19.3 2.0 1.2 10.5 10.3 9.9 15.7 12.5 7.8 7.0 3.3 4.8 3.2 8.6 3.9 52.5 5.9 3.3 13.6 14.8 7.8 1.4 1.5 1.3 1.3 2.0 0.2 422.4 4.0 3.6 1.8 2.2 10.9 0.6 0.3 9.1 2.8 0.2 0.5 1.8 19.2 1.6 0.2 2.4 0.0 0.1 11.3 1.5 0.2 11.0 4.7 4.5 7.5 1.8 0.5 199.1 0.0 0.0 0.1 55.6 0.9 0.0 0.5 2.1 0.1 3.4 0.2 51.3 0.0 0.5 1.0 31.0 17.0 0.0 0.8 7.7 25.0 0.1 0.5 40.6 0.3 10.2 0.1 17.0 0.4 0.2 0.7 6.3 0.5 0.5 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 7.4 7.6 7.3 11.7 8.7 20.6 9.5 15.7 9.3 7.0 8.6 7.8 32.4 9.6 4.6 1.0 1.0 24.6 10.3 111.4 34.7 1.3 8.9 16.0 3.6 0.0 26.0 0.0 14.6 83.8 2.4 2.0 0.0 2.7 0.1 1.1 3.3 169.4 7.1 2.7 0.1 0.5 1604.4 30.8 1.1 0.8 6.3 0.2 5.3 0.3 37.4 0.0 0.2 2.1 18.3 0.6 8.9 0.8 13.1 2.1 21.4 0.0 0.0 1.9 0.0 0.0 0.2 0.5 1.2 19.5 0.2 3.2 0.6 1.1 12.1 7.8 105.2 7.1 86.4 0.2 6.8 8.1 19.6 2122.6 3.0 3.0 2.3 5.8 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 318.7;brain: 394.8" "Cell type enhanced" "Detected in some" "Adipocytes: 80.5;Cardiomyocytes: 151.9;Cytotrophoblasts: 137.4;Extravillous trophoblasts: 365.5;Hofbauer cells: 71.0;Syncytiotrophoblasts: 290.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 187.8" "Group enriched" "Detected in all" 6 "dendritic cells: 187.8;T-cells: 55.0" "Cell line enhanced" "Detected in many" "A549: 135.1;ASC diff: 148.2;CAPAN-2: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" 318.7 36.2 208.5 10.2 287.0 3.1 166.8 234.7 261.6 13.3 142.8 32.8 8.7 17.6 26.6 13.2 33.0 29.1 103.0 197.7 215.3 65.0 76.5 37.6 11.6 283.0 250.7 73.4 32.4 28.6 33.4 40.3 279.8 16.4 7.6 26.6 28.9 29.9 108.9 10.7 21.8 15.8 241.2 15.9 31.9 54.7 237.1 7.1 41.2 118.7 4.4 26.7 9.6 394.8 87.7 135.1 3.7 0.2 148.2 25.1 24.1 3.2 26.9 22.3 11.2 30.8 247.1 0.0 55.3 6.9 72.4 4.4 127.4 6.8 16.9 108.0 5.0 1.3 33.3 5.4 87.8 0.0 1.3 15.2 0.7 55.4 2.2 88.1 35.4 0.0 1.6 9.6 24.0 15.3 0.2 0.6 10.8 55.0 43.0 0.0 0.0 8.7 71.2 12.3 1.7 9.7 18.0 51.5 28.7 54.6 111.6 4.5 52.2 10.0 0.7 34.0 7.7 39.6 28.0 0.3 40.1 0.0 1.0 0.1 21.1 0.1 55.0 9.1 30.3 7.4 12.1 40.5 6.4 1.2 3.9 30.0 1.3 21.0 0.6 187.8 9.3 27.2 208.5 287.0 234.7 261.6 197.7 215.3 283.0 250.7 279.8 241.2 237.1 394.8 80.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.9 0.0 0.0 0.0 0.0 137.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 365.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 290.6 2.0 0.0 0.0 0.0 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 236.8;Sertoli cells: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" 58.1 34.6 46.3 35.2 51.2 16.1 41.2 48.6 56.6 65.4 46.4 47.3 37.7 65.0 30.5 21.3 51.1 42.0 71.2 44.5 47.4 45.5 78.1 44.4 15.4 49.6 50.8 54.4 39.0 36.9 29.6 83.8 52.4 34.7 23.2 10.6 75.9 40.6 40.5 27.2 35.6 78.4 44.8 31.5 35.5 11.6 52.2 7.9 34.9 41.6 12.9 42.4 36.0 53.1 112.5 91.4 51.3 239.7 343.4 190.6 39.0 330.4 436.1 170.4 287.1 105.2 71.5 63.1 339.5 367.3 125.9 93.4 75.6 115.6 115.6 66.2 78.3 34.0 136.6 137.3 212.5 21.9 162.7 234.0 59.7 206.2 81.9 573.3 305.0 14.8 97.6 30.9 180.2 71.1 5.7 58.6 22.9 115.4 131.6 25.8 100.0 141.0 98.7 24.3 19.2 77.7 137.3 97.4 164.8 80.4 48.3 55.9 298.7 190.1 141.6 236.3 161.9 71.4 123.7 38.7 425.1 75.5 316.8 0.0 40.3 2.0 17.3 34.4 3.1 1.7 3.0 8.4 32.7 3.4 1.2 6.4 35.5 5.4 32.3 4.9 2.0 22.6 46.3 51.2 48.6 56.6 44.5 47.4 49.6 50.8 52.4 44.8 52.2 53.1 19.4 0.0 7.9 9.4 3.7 7.0 8.0 22.8 8.0 5.7 17.9 17.5 18.3 8.6 8.6 11.0 2.1 39.7 8.7 14.8 3.9 30.3 1.0 11.0 62.2 33.9 8.4 3.0 4.2 9.8 236.8 47.5 17.3 24.8 0.0 20.4 36.8 37.1 46.3 6.7 5.8 12.5 4.1 26.5 8.3 2.4 44.4 16.3 10.6 15.9 17.9 7.9 15.5 3.0 9.8 22.4 15.4 24.5 19.4 8.0 41.5 16.7 4.5 3.1 105.2 77.2 47.3 0.5 3.3 7.4 5.1 33.7 5.5 37.1 16.6 3.9 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 115.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 20.3;monocytes: 22.5;T-cells: 12.6" "Cell line enhanced" "Detected in all" "Karpas-707: 695.6;WM-115: 680.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted to extracellular matrix" NA NA 1600000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 41.9 27.3 43.6 22.9 53.2 19.6 32.8 54.9 58.5 33.3 46.8 37.8 25.7 38.9 11.7 12.2 32.5 18.8 42.6 43.6 46.3 36.3 54.1 37.5 14.6 61.1 52.3 26.3 41.8 21.5 27.1 35.0 58.9 24.2 15.3 3.9 19.4 18.6 15.3 19.1 35.9 26.0 49.4 35.3 30.0 12.9 51.7 8.0 25.3 11.8 7.5 35.2 25.2 71.9 71.7 62.4 27.1 168.2 116.2 83.9 51.4 125.5 135.9 122.7 88.6 98.0 89.0 5.6 140.2 211.4 100.7 83.0 50.0 72.0 31.2 37.8 23.8 7.2 70.7 97.3 157.6 31.5 57.4 90.8 67.6 71.6 55.4 120.2 110.9 4.6 68.4 695.6 84.2 194.5 3.4 72.1 53.5 120.5 94.9 21.8 35.1 108.3 42.0 19.1 21.2 116.0 81.1 116.2 288.1 66.8 21.9 105.2 100.5 188.1 94.9 228.1 155.0 38.5 75.9 5.2 112.4 74.2 680.2 0.0 18.1 4.4 12.6 21.8 10.9 3.7 9.3 8.3 16.5 2.2 4.1 4.5 1.8 3.6 22.5 20.3 6.7 9.5 43.6 53.2 54.9 58.5 43.6 46.3 61.1 52.3 58.9 49.4 51.7 71.9 34.1 22.4 8.7 11.1 9.7 8.9 10.8 18.9 8.0 5.7 8.1 9.1 16.1 21.5 8.7 25.8 14.6 20.4 22.0 37.6 1.9 40.2 0.6 10.8 29.9 28.5 16.2 19.1 11.9 31.6 71.6 34.2 17.9 20.5 19.7 25.9 26.7 18.3 50.1 8.4 10.8 18.0 4.1 23.3 18.3 2.1 26.1 23.2 62.2 4.7 18.9 7.7 12.3 10.1 33.4 36.1 37.8 14.7 19.7 8.0 45.8 8.8 9.3 7.3 19.7 14.3 29.8 8.9 12.4 1.9 4.8 18.9 12.5 18.4 27.3 5.2 POLR1G "A34.5, ASE-1, CAST, CD3EAP, PAF49, RPA34" ENSG00000117877 "RNA polymerase I subunit G" O15446 19 45406644-45410737 "Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 15.8;Extravillous trophoblasts: 26.3;Hofbauer cells: 11.5;Syncytiotrophoblasts: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.5" "Lineage enriched" "Detected in all" 4 "dendritic cells: 14.5" "Cell line enhanced" "Detected in all" "U-251 MG: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041664, HPA041734" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA041664: AB_10795693, HPA041734: AB_10794489" "unprognostic (1.03e-1)" "unprognostic (8.98e-2)" "unprognostic (9.28e-2)" "unprognostic (1.37e-3)" "unprognostic (2.46e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (4.79e-9)" "unprognostic (1.62e-3)" "unprognostic (3.21e-1)" "unprognostic (5.01e-2)" "unprognostic (2.99e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-9)" "unprognostic (1.02e-1)" "unprognostic (2.81e-1)" "unprognostic (1.38e-2)" "unprognostic (4.53e-2)" 3.2 2.4 2.9 3.3 3.0 2.1 3.1 4.1 4.3 2.4 1.1 2.5 2.4 2.7 1.4 4.3 3.0 2.8 3.5 2.9 2.4 2.7 2.6 2.0 3.5 3.4 2.6 3.5 3.8 2.9 1.9 2.2 3.6 2.2 2.1 2.7 2.8 1.9 6.7 4.4 1.9 3.0 1.1 2.1 1.8 1.8 3.4 2.1 2.3 4.5 4.0 4.1 2.4 3.8 31.4 29.0 5.3 20.6 7.5 6.5 20.3 15.3 5.2 26.2 15.1 32.5 21.5 48.3 14.8 11.3 20.6 29.5 46.4 43.0 18.4 22.1 28.7 24.3 11.0 23.9 12.8 25.3 8.9 9.4 27.3 38.2 20.7 7.0 19.2 16.0 63.0 8.9 25.6 37.0 18.7 9.3 37.0 34.6 27.3 25.1 19.5 32.2 10.5 22.7 30.8 9.6 30.9 40.6 6.4 10.6 19.9 15.4 18.2 36.5 36.7 20.4 200.5 16.1 74.0 51.6 16.8 37.6 25.9 1.5 2.7 0.3 1.4 3.5 3.1 2.7 2.0 2.2 4.2 3.0 2.9 3.5 1.3 3.3 2.8 14.5 1.3 2.0 2.9 3.0 4.1 4.3 2.9 2.4 3.4 2.6 3.6 1.1 3.4 3.8 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 15.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 26.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 7.7 0.1 0.0 0.0 0.0 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706121-100707486 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 25.6 31.7 30.1 18.1 31.6 33.9 26.6 33.4 38.6 24.2 23.8 27.9 19.3 27.7 11.0 34.0 21.3 9.8 37.6 32.3 30.8 25.8 67.1 18.2 17.3 30.1 27.8 18.1 31.3 16.6 22.8 16.6 30.8 22.6 9.2 9.6 29.0 13.5 69.0 50.2 22.3 12.1 29.4 22.7 26.4 12.5 29.1 15.6 16.8 31.9 12.0 25.4 24.9 33.9 115.7 115.3 47.2 78.4 25.1 23.9 92.0 65.6 32.4 73.7 73.1 159.8 71.0 97.5 105.1 30.0 81.4 70.4 70.1 79.5 36.8 82.7 212.4 44.9 75.0 166.5 42.1 69.2 49.8 27.6 30.2 76.2 74.8 20.9 41.6 68.9 157.4 77.8 39.8 330.4 158.0 232.9 135.2 77.8 164.4 123.6 50.0 159.4 45.3 65.2 90.4 92.3 54.5 156.2 78.7 42.0 50.0 66.2 41.3 92.0 117.7 191.0 127.6 34.0 99.4 175.8 61.0 115.1 104.6 106.3 63.2 72.4 54.7 64.7 50.7 60.3 54.6 54.3 55.3 47.7 49.5 52.0 39.0 78.9 70.3 51.2 69.8 62.5 30.1 31.6 33.4 38.6 32.3 30.8 30.1 27.8 30.8 29.4 29.1 33.9 30.5 19.2 17.0 2.9 29.7 105.0 32.0 57.2 56.3 26.1 61.6 64.1 27.9 37.1 31.5 35.0 6.2 148.2 25.8 51.8 93.9 75.4 2.1 31.2 32.3 37.2 40.2 50.1 5.2 87.4 181.3 37.3 25.0 35.1 17.7 32.4 33.5 99.0 66.1 32.0 6.0 61.7 67.1 27.3 40.7 7.9 42.0 22.4 56.9 2.8 38.7 41.8 41.2 4.0 5.8 92.2 47.6 37.2 55.1 75.6 69.8 86.1 27.8 21.3 46.0 29.8 52.2 9.2 45.5 74.7 119.2 139.3 27.2 39.9 55.8 43.5 PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36874803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 58.7;Extravillous trophoblasts: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062916 Supported Nucleoli NA NA 21000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli "HPA062916: AB_2684904" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-3)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (2.01e-1)" "unprognostic (3.37e-2)" "prognostic favorable (4.90e-4)" "unprognostic (6.58e-2)" "unprognostic (5.49e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-2)" 12.4 21.7 20.3 19.1 21.9 11.4 18.4 22.6 27.3 15.0 23.8 14.7 13.2 15.7 19.1 17.0 23.0 10.7 42.8 20.0 25.2 18.9 21.5 10.5 21.9 22.0 22.0 17.7 14.3 21.7 12.0 22.3 23.3 16.8 17.6 29.1 19.5 17.6 18.5 9.5 11.3 22.9 24.1 9.5 12.9 23.2 22.2 18.6 33.2 20.7 24.6 20.5 8.0 22.8 69.2 50.0 111.2 78.5 19.7 31.5 77.5 60.9 41.0 82.7 70.0 89.7 39.7 87.7 75.5 41.9 105.5 55.4 135.1 92.7 96.2 81.3 114.6 102.7 33.6 147.7 53.5 89.3 40.8 24.7 48.7 62.3 118.9 31.8 75.5 79.1 202.4 48.0 63.3 71.2 101.9 69.8 92.3 108.5 57.9 79.4 100.2 92.0 63.2 53.5 140.0 68.5 41.8 51.4 102.5 83.5 76.3 100.2 44.0 66.7 69.0 58.5 98.8 57.0 145.2 153.0 23.7 183.7 139.4 1.6 4.8 1.3 14.7 6.2 19.7 10.3 12.1 13.9 9.2 7.4 13.4 15.9 1.2 7.3 3.4 7.8 10.2 9.8 20.3 21.9 22.6 27.3 20.0 25.2 22.0 22.0 23.3 24.1 22.2 22.8 5.7 6.4 7.5 2.9 10.8 3.1 18.6 12.2 5.7 16.9 9.0 10.5 45.8 8.6 8.3 5.5 4.2 58.7 6.6 3.3 23.5 25.7 32.0 10.3 14.2 12.3 3.6 22.7 6.5 20.3 72.3 12.2 7.7 7.7 10.8 16.3 5.0 8.2 30.1 16.8 8.6 11.4 4.1 3.3 3.6 11.7 6.8 6.4 7.2 1.9 9.2 41.0 11.3 7.5 5.4 22.1 5.5 12.4 15.0 13.5 3.3 17.1 13.5 15.5 6.6 6.1 12.8 25.7 51.0 10.6 4.5 25.3 9.2 21.1 11.9 8.6 PPM1N FLJ40125 ENSG00000213889 "Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)" Q8N819 19 45488777-45502510 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "skeletal muscle: 213.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 123.1;Rod photoreceptor cells: 74.3" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "non-classical monocyte: 142.4" "Lineage enriched" "Detected in all" 11 "monocytes: 142.4" "Cell line enhanced" "Detected in many" "OE19: 24.1;RT4: 29.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043577 Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA043577: " "unprognostic (2.38e-2)" "unprognostic (1.11e-2)" "unprognostic (8.53e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (9.27e-2)" "unprognostic (2.48e-2)" "unprognostic (1.11e-16)" "unprognostic (3.42e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (1.86e-3)" 2.0 0.8 15.5 2.0 14.7 2.6 3.3 14.5 19.9 2.0 14.5 2.6 0.6 0.7 1.3 2.6 0.9 1.4 1.3 15.1 15.0 1.4 2.6 2.5 3.0 14.7 14.7 0.6 0.5 2.1 1.1 4.7 15.1 1.2 1.3 25.8 0.9 2.0 213.3 3.1 1.6 1.2 13.7 9.2 2.8 5.3 14.3 2.3 1.1 0.2 3.4 2.4 1.6 16.2 2.6 7.1 1.2 5.1 5.9 7.8 14.7 1.9 3.0 0.6 2.3 1.7 15.8 11.1 3.2 1.8 4.1 7.6 3.0 2.2 0.9 10.9 4.5 9.0 2.7 1.9 1.4 0.8 18.1 3.2 3.6 3.1 1.9 4.0 1.0 4.4 10.3 9.6 1.0 1.9 3.1 4.6 4.0 24.1 1.4 2.0 1.5 3.0 3.4 29.9 5.8 6.8 1.0 11.1 9.2 8.8 3.8 2.7 1.5 8.2 4.7 4.3 1.4 1.7 4.5 2.3 6.1 2.3 7.2 6.7 4.4 3.2 6.4 22.5 5.5 6.3 3.9 6.2 12.8 3.6 4.3 7.9 6.5 3.1 142.4 2.4 4.5 5.7 15.5 14.7 14.5 19.9 15.1 15.0 14.7 14.7 15.1 13.7 14.3 16.2 6.4 0.0 2.7 1.0 7.5 3.4 14.7 6.2 17.6 14.1 5.9 32.5 2.3 17.2 2.5 3.7 31.3 3.2 6.0 5.5 0.0 2.9 12.5 2.0 3.9 3.5 3.0 0.8 1.1 1.8 123.1 6.5 3.1 7.4 7.0 1.0 5.3 1.3 20.1 1.7 1.4 4.2 0.0 15.5 15.7 4.9 0.9 15.2 1.8 1.0 6.1 7.3 20.6 0.0 0.3 3.1 4.7 0.7 1.7 6.7 6.9 0.6 0.8 74.3 0.0 25.6 5.5 2.9 9.1 3.4 4.1 8.5 7.5 0.3 3.1 8.4 PRG2 "BMPG, MBP, proMBP" ENSG00000186652 "Proteoglycan 2, pro eosinophil major basic protein" P13727 11 57386780-57390650 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Immunity "Antibiotic, Antimicrobial, Heparin-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 2616.3" "Group enriched" "Detected in some" 10 "Erythroid cells: 44.3;Extravillous trophoblasts: 107.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 36 "basophil: 7.2" "Lineage enriched" "Detected in single" 73 "granulocytes: 7.2" "Group enriched" "Detected in some" 62 "HL-60: 3328.5;HMC-1: 5009.7;NB-4: 10560.9" "Not detected" "Not detected" HPA038515 Supported "Secreted in female reproductive system" NA NA 100000000 "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 24: NB-4 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA038515: AB_10675800" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (3.39e-2)" "unprognostic (3.49e-1)" "unprognostic (8.62e-4)" "unprognostic (4.77e-3)" "unprognostic (3.20e-2)" "unprognostic (4.17e-2)" "unprognostic (2.26e-2)" "unprognostic (5.19e-3)" "unprognostic (2.17e-1)" "unprognostic (1.40e-11)" "unprognostic (4.26e-2)" "unprognostic (4.52e-3)" "unprognostic (6.47e-2)" "unprognostic (2.32e-1)" 0.7 0.0 0.0 0.1 0.0 215.8 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 2.5 1.1 1.4 0.0 0.0 0.3 3.8 0.0 0.2 2616.3 0.0 0.0 0.4 0.0 0.9 0.0 0.2 2.1 0.4 0.5 0.0 3.0 0.3 0.0 0.0 8.7 0.2 0.0 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 101.3 0.0 0.0 0.2 3328.5 5009.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 9.0 0.6 0.0 0.0 0.8 10560.9 0.0 0.0 0.0 0.3 0.8 1.0 0.0 0.0 1.6 4.2 0.4 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.4 0.2 0.4 0.3 7.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 44.3 0.0 0.0 107.2 0.5 0.0 0.0 6.3 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 403.5;Extravillous trophoblasts: 648.4;Paneth cells: 262.6;Proximal enterocytes: 358.0;Syncytiotrophoblasts: 450.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 243.7;CACO-2: 165.9;CAPAN-2: 111.9;hTCEpi: 157.8;OE19: 79.6;SK-BR-3: 186.3" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in single" HPA030436 Uncertain "Secreted - unknown location" NA NA 4400000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.8 0.4 0.3 15.0 0.4 0.2 25.5 2.1 0.6 31.1 6.7 129.4 155.7 9.9 113.0 136.2 15.4 47.7 0.4 0.6 0.2 90.6 28.0 54.1 0.3 0.3 0.2 0.6 139.4 56.0 8.4 51.0 0.4 49.0 72.6 0.0 245.4 8.5 0.3 115.3 151.8 3.5 0.1 0.2 156.2 0.5 0.2 15.4 50.8 0.0 11.8 4.9 56.0 0.2 63.4 0.2 0.1 0.2 0.0 0.0 243.7 0.0 0.0 0.0 0.0 165.9 111.9 0.0 1.3 0.0 0.0 73.5 0.1 69.7 0.0 0.3 0.4 0.1 0.3 6.5 0.0 0.0 0.3 0.0 157.8 0.0 2.4 0.0 0.0 0.1 1.9 0.1 0.0 68.1 0.6 1.4 20.5 79.6 0.1 0.5 0.0 1.2 7.5 13.1 0.9 0.7 0.0 186.3 0.1 18.8 42.8 0.8 0.0 0.1 1.9 0.6 0.4 0.3 0.5 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.1 0.6 0.6 0.2 0.3 0.2 0.4 0.1 0.2 0.2 0.4 99.3 60.1 0.0 1.0 37.9 82.7 108.9 76.2 0.5 74.4 39.2 0.3 62.9 107.4 42.3 0.0 168.8 0.8 403.5 29.4 192.4 0.0 35.2 11.4 2.6 9.6 2.7 0.1 224.4 648.4 3.5 82.6 109.5 7.0 0.0 0.0 18.2 22.8 0.0 0.2 132.1 87.5 0.3 2.7 0.0 0.6 1.9 3.6 0.0 4.2 0.3 0.0 0.0 0.0 240.7 262.6 0.0 0.1 66.0 358.0 28.6 21.2 0.1 0.0 0.1 4.7 0.0 0.2 81.9 54.0 450.7 2.2 0.0 150.8 91.0 PSPC1 "FLJ10955, PSP1" ENSG00000121390 "Paraspeckle component 1" Q8WXF1 13 19674752-19783019 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 173.4;Inhibitory neurons: 164.7;Spermatocytes: 171.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038904 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "HPA038904: AB_10673291" "unprognostic (2.13e-3)" "unprognostic (3.48e-1)" "unprognostic (1.52e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-3)" "unprognostic (2.14e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.13e-3)" "unprognostic (9.57e-2)" "unprognostic (1.09e-1)" "unprognostic (1.69e-3)" "unprognostic (3.04e-3)" "unprognostic (2.92e-1)" "unprognostic (3.69e-2)" "unprognostic (8.61e-2)" "prognostic favorable (1.46e-4)" "unprognostic (7.72e-2)" 10.9 13.0 11.5 13.2 11.5 53.7 16.2 12.8 13.9 12.5 9.9 14.9 12.4 14.8 21.7 14.0 16.2 12.1 11.1 11.8 10.6 12.2 8.9 9.9 20.8 12.1 9.0 13.7 9.5 9.5 10.3 13.8 10.6 11.0 15.5 17.4 10.0 8.3 20.9 14.4 12.4 12.6 8.7 11.1 12.0 25.0 10.5 23.1 12.2 12.7 21.9 20.4 10.0 15.8 50.5 20.4 46.6 23.3 18.9 19.8 60.3 26.1 34.0 48.3 43.6 68.4 27.8 67.8 27.7 27.9 25.4 24.6 54.7 32.2 50.0 28.9 27.3 76.4 14.1 83.1 37.4 55.3 46.7 31.6 6.5 29.8 32.9 19.2 41.7 65.9 42.8 26.1 43.2 54.1 65.5 52.8 65.5 27.3 28.0 43.7 46.8 34.6 50.8 74.6 42.7 22.0 35.8 59.1 23.1 44.9 34.5 56.6 25.1 28.9 27.7 28.0 25.4 22.5 14.5 115.1 13.2 32.7 35.2 14.8 21.3 14.5 11.8 22.7 12.0 23.3 15.1 11.0 19.1 22.5 15.4 11.2 16.9 11.9 18.1 20.9 21.8 15.7 11.5 11.5 12.8 13.9 11.8 10.6 12.1 9.0 10.6 8.7 10.5 15.8 21.0 19.2 29.5 79.3 36.4 33.3 24.9 16.4 23.3 43.2 24.6 21.0 28.6 21.5 18.9 16.5 58.4 70.0 41.0 16.4 21.5 31.3 17.4 40.0 33.9 24.0 25.2 23.1 173.4 34.1 104.7 25.1 25.5 39.4 9.5 28.0 23.9 11.1 27.2 30.3 164.7 20.0 12.2 25.7 25.3 21.4 31.4 27.7 19.6 92.8 45.2 25.5 27.8 115.6 156.4 26.8 22.2 26.7 31.8 16.5 16.1 23.8 25.9 69.1 32.9 27.2 27.4 171.5 75.4 24.0 34.1 80.4 38.9 48.1 27.2 26.2 PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 84.2;urinary bladder: 78.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.2;Cytotrophoblasts: 146.0;Extravillous trophoblasts: 293.1;Syncytiotrophoblasts: 276.2" "Cancer enhanced" "Detected in all" "urothelial cancer: 69.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 28.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "ASC diff: 147.7;BEWO: 162.7;GAMG: 292.8;HaCaT: 216.3;SK-BR-3: 157.6;U-2197: 404.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" 36.7 1.4 4.1 13.9 3.6 7.8 25.5 3.9 4.5 26.1 3.5 9.2 2.8 3.7 19.0 17.8 5.4 9.0 8.5 4.5 5.1 8.1 0.7 7.8 7.6 6.1 5.8 2.2 1.6 42.1 1.9 58.4 7.1 13.7 4.2 0.0 30.8 84.2 1.3 42.3 9.1 4.1 4.1 2.5 7.1 16.9 4.7 4.2 3.7 1.1 30.7 78.6 20.0 3.5 1.5 94.9 0.1 46.6 147.7 51.9 162.7 7.4 64.2 1.1 1.7 5.6 71.7 0.1 2.7 18.0 292.8 216.3 0.7 7.2 0.6 0.3 0.5 0.0 62.5 0.4 3.5 0.0 0.0 30.9 49.0 0.9 0.3 1.4 0.0 0.9 0.0 0.1 0.7 1.7 0.2 0.0 1.2 46.7 8.2 0.2 0.0 0.3 5.3 102.2 0.8 3.6 87.1 157.6 0.8 6.3 83.3 0.0 0.5 0.1 0.4 404.8 0.0 0.0 0.0 0.0 78.8 0.1 0.7 28.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 4.0 0.0 0.0 0.3 4.1 3.6 3.9 4.5 4.5 5.1 6.1 5.8 7.1 4.1 4.7 3.5 3.4 0.0 0.0 0.3 0.3 17.8 8.9 101.2 10.8 0.0 29.7 19.7 0.1 0.0 53.2 3.7 0.0 146.0 0.6 0.0 1.9 13.4 0.6 1.6 2.3 4.0 7.3 0.0 1.0 1.1 293.1 70.7 0.0 5.0 1.3 61.5 0.0 0.0 17.5 0.0 2.8 6.6 30.5 0.0 21.6 0.4 0.3 13.2 14.2 7.5 7.2 0.0 0.0 0.0 0.2 8.1 0.2 0.0 0.3 8.2 0.3 0.5 6.7 0.0 0.0 0.8 13.5 0.3 0.0 5.5 43.0 276.2 0.8 0.2 0.4 49.2 PXN ENSG00000089159 Paxillin P49023 12 120210439-120265771 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003841, HPA051309" Supported Enhanced "Focal adhesion sites,Centrosome,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Focal adhesion sites" "Centrosome, Cytosol" "CAB003841: AB_562188, HPA051309: AB_2681436" "unprognostic (4.00e-2)" "unprognostic (1.94e-2)" "unprognostic (3.51e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (1.09e-4)" "prognostic unfavorable (3.72e-5)" "prognostic unfavorable (7.12e-5)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.12e-2)" "unprognostic (9.19e-3)" "unprognostic (2.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" 83.1 60.9 28.7 49.1 30.8 81.4 74.4 27.6 30.5 64.5 33.7 69.0 55.7 56.3 18.7 30.9 72.3 38.2 84.2 28.0 28.5 70.2 29.5 84.6 29.3 37.1 30.8 28.5 34.5 27.8 29.5 73.3 30.3 58.9 49.9 61.8 49.4 40.6 119.2 45.6 61.1 44.5 31.8 72.5 47.5 26.5 36.6 25.9 58.1 46.1 18.4 75.8 53.2 29.2 182.4 87.5 31.3 30.1 60.4 158.1 206.1 151.8 128.6 118.9 61.5 102.5 108.9 12.2 94.6 154.9 115.1 126.0 21.7 272.0 93.0 9.9 18.6 2.3 63.8 37.9 86.8 2.7 3.6 76.5 176.2 125.3 143.9 139.7 211.6 32.2 32.4 19.5 239.3 119.6 11.1 4.1 43.5 77.1 300.8 26.2 51.0 10.8 121.4 171.9 48.7 14.5 133.2 40.3 81.7 72.1 96.1 14.8 289.9 78.9 86.7 103.6 183.9 20.4 12.3 4.6 228.9 27.0 159.2 40.8 44.2 49.2 84.5 15.7 45.3 1.7 38.4 56.0 26.2 1.1 29.5 40.3 169.6 51.8 0.8 4.1 31.4 60.6 28.7 30.8 27.6 30.5 28.0 28.5 37.1 30.8 30.3 31.8 36.6 29.2 93.6 57.7 27.9 11.8 3.0 42.3 40.6 32.8 15.4 7.8 20.3 22.9 14.7 22.8 33.3 42.3 33.3 40.8 61.6 83.1 19.6 31.6 2.1 26.0 16.7 71.0 54.6 6.1 5.1 40.2 152.4 29.7 37.2 28.8 18.3 6.2 62.2 17.2 34.2 11.8 7.7 52.7 24.4 42.3 23.7 2.8 24.2 23.5 26.6 19.7 36.8 9.1 99.9 13.0 9.2 84.8 51.6 18.8 14.5 41.7 56.6 14.6 40.0 33.6 6.6 16.7 12.1 3.5 9.1 8.1 19.5 25.0 34.4 11.3 35.8 42.6 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1616.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1918.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 84.8 84.9 35.8 52.1 39.4 115.5 53.2 42.7 47.3 81.7 41.1 100.1 67.5 75.2 70.2 178.4 82.3 150.3 244.9 41.5 43.4 73.8 81.7 200.0 16.3 50.0 40.7 196.1 136.3 21.0 60.2 158.9 43.2 92.3 80.9 15.2 105.6 57.5 91.2 58.6 85.7 60.0 44.0 61.9 178.3 172.9 42.6 12.1 31.9 46.0 19.6 174.1 108.7 57.7 441.4 62.0 14.8 181.0 179.1 367.8 712.5 456.5 456.6 381.6 267.1 7.3 137.7 6.8 276.7 367.8 52.6 93.7 17.6 123.5 185.0 26.4 28.0 14.1 33.6 19.4 1918.6 48.6 129.2 197.9 55.5 408.0 484.3 499.9 569.4 32.1 20.2 66.3 255.3 76.4 10.4 89.7 49.4 302.6 174.6 19.7 33.0 11.8 63.1 123.6 51.9 52.6 133.8 179.8 91.9 32.2 33.0 226.3 678.3 473.8 187.5 322.0 392.9 48.3 84.4 12.2 180.9 153.9 146.0 16.2 53.1 20.6 14.0 29.9 10.2 5.4 9.1 9.6 39.2 3.2 8.1 8.0 40.2 16.9 28.6 8.0 11.5 28.6 35.8 39.4 42.7 47.3 41.5 43.4 50.0 40.7 43.2 44.0 42.6 57.7 36.6 57.7 101.6 8.5 7.7 13.8 27.4 81.2 7.4 11.5 86.2 47.9 48.3 51.5 112.5 71.7 25.0 19.5 10.7 138.1 0.0 230.4 49.2 49.2 19.4 41.7 46.2 6.9 17.2 130.1 1616.7 78.0 136.6 80.4 25.4 27.1 89.3 4.3 68.6 6.7 17.0 185.7 132.2 45.2 35.3 20.1 177.7 48.9 44.4 8.4 49.7 53.5 10.3 24.6 23.9 249.8 165.6 71.1 12.8 35.7 9.0 9.1 47.8 6.7 32.9 13.6 31.3 30.2 32.7 10.2 9.9 154.3 13.9 13.9 89.9 68.0 RAC3 ENSG00000169750 "Rac family small GTPase 3" P60763 17 82031678-82034204 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 45.0;Extravillous trophoblasts: 152.1;Spermatogonia: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "CACO-2: 230.8;HEK 293: 274.7;NB-4: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047820 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA047820: AB_2680167" "unprognostic (3.48e-2)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (6.21e-5)" "unprognostic (1.62e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (3.36e-2)" "unprognostic (1.57e-1)" "unprognostic (6.62e-2)" "unprognostic (1.22e-2)" "unprognostic (3.67e-1)" "unprognostic (4.39e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.25e-3)" 12.3 5.0 22.8 1.8 20.8 7.7 13.7 26.3 29.5 5.3 9.3 4.8 3.4 2.8 7.3 10.9 3.8 3.0 3.0 19.7 24.5 9.4 20.7 4.0 1.7 23.3 22.3 4.8 4.7 9.3 22.8 5.6 27.0 11.1 1.4 2.8 18.1 4.2 0.8 12.4 3.7 1.3 15.3 1.9 11.8 28.1 26.5 2.2 9.8 0.2 1.5 3.1 7.6 20.6 11.1 15.1 45.6 63.1 9.7 18.2 50.5 7.8 7.2 26.1 22.3 230.8 21.4 5.8 11.5 4.8 1.7 15.6 43.0 17.8 4.1 3.6 274.7 64.6 20.2 16.7 47.0 28.0 12.2 27.5 13.0 3.5 12.0 19.5 60.3 33.8 103.1 30.2 10.8 35.6 7.3 156.4 61.4 39.2 27.6 47.6 4.5 27.7 20.0 5.4 109.8 111.5 4.1 57.2 55.7 16.1 58.6 40.7 21.6 10.8 9.8 5.5 12.1 14.6 9.9 4.4 6.6 17.3 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 22.8 20.8 26.3 29.5 19.7 24.5 23.3 22.3 27.0 15.3 26.5 20.6 1.6 0.0 0.0 2.3 0.9 8.7 16.3 12.2 19.9 5.3 36.9 45.0 0.2 4.3 3.6 5.5 0.0 30.0 1.8 3.3 21.5 9.8 19.1 5.9 5.4 2.3 3.0 6.9 5.2 3.3 152.1 10.7 8.2 12.6 4.5 17.8 1.4 11.3 9.7 6.7 8.3 5.1 22.4 0.0 2.6 16.6 5.6 0.9 14.2 0.0 2.0 6.0 0.0 3.5 2.0 5.5 2.4 1.9 2.6 16.4 4.2 26.0 2.4 7.3 0.0 0.8 5.3 2.2 58.0 15.8 7.5 14.1 3.1 8.6 5.2 8.4 RALBP1 "RIP, RIP1, RLIP76" ENSG00000017797 "RalA binding protein 1" Q15311 18 9475009-9538114 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transport "GTPase activation, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Collecting duct cells: 480.1;Extravillous trophoblasts: 518.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 195.6" "Lineage enriched" "Detected in all" 10 "granulocytes: 195.6" "Cell line enhanced" "Detected in all" "OE19: 239.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046010, HPA046651" Approved Approved "Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Nuclear membrane, Vesicles" "CAB046010: AB_11126824, HPA046651: AB_2679738" "unprognostic (1.23e-1)" "unprognostic (5.84e-3)" "unprognostic (1.58e-1)" "unprognostic (1.74e-2)" "unprognostic (8.24e-2)" "unprognostic (1.12e-1)" "unprognostic (5.72e-2)" "unprognostic (9.90e-2)" "unprognostic (1.53e-1)" "prognostic favorable (8.47e-4)" "unprognostic (4.03e-3)" "unprognostic (1.76e-1)" "prognostic favorable (5.39e-6)" "unprognostic (1.28e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (1.26e-1)" 29.7 20.4 42.7 23.4 44.1 30.7 27.8 45.8 82.2 26.8 38.6 34.1 18.7 22.1 23.5 50.3 24.8 20.3 28.5 40.7 45.1 42.7 19.9 22.6 24.0 44.1 48.0 26.3 15.4 47.9 16.8 31.4 44.4 32.6 25.4 13.5 25.0 48.2 38.5 75.9 20.4 21.1 43.6 26.5 25.7 13.0 45.3 29.3 22.9 32.5 25.4 33.8 33.3 45.1 58.9 37.6 34.2 39.0 38.3 60.7 43.3 67.7 38.1 35.6 38.0 42.6 57.5 70.5 47.0 64.8 50.2 32.8 48.1 52.7 44.2 71.4 38.5 38.5 34.6 32.7 31.2 114.8 43.0 42.0 52.2 49.6 48.7 47.7 60.6 64.6 53.7 67.7 56.2 46.3 70.7 50.9 25.4 239.5 31.9 93.6 59.4 54.2 48.4 80.7 44.7 34.8 58.2 52.8 30.9 52.3 32.9 53.8 67.4 105.0 76.9 72.3 81.9 38.7 42.9 77.9 45.6 53.4 40.5 13.0 9.6 15.7 10.3 10.6 8.7 9.9 8.7 8.8 8.7 7.5 7.3 9.4 195.6 14.8 17.8 19.8 6.4 4.5 42.7 44.1 45.8 82.2 40.7 45.1 44.1 48.0 44.4 43.6 45.3 45.1 101.8 57.7 35.7 15.3 48.0 156.4 80.9 59.9 112.7 42.6 96.0 102.2 64.8 88.6 64.6 480.1 29.2 104.2 70.9 122.6 123.3 119.4 16.1 99.1 82.6 86.9 74.2 175.7 25.4 90.7 518.6 71.6 56.1 179.4 40.5 85.8 78.9 88.3 70.1 52.2 26.7 87.7 109.9 92.8 69.7 9.5 72.7 78.4 58.7 20.6 99.6 47.6 83.4 17.1 25.3 166.3 78.2 87.3 63.2 174.4 61.0 115.0 38.6 37.3 65.7 76.8 105.6 66.7 80.0 149.6 242.5 44.6 62.6 128.4 90.1 216.4 RFPL4B RNF211 ENSG00000251258 "Ret finger protein like 4B" Q6ZWI9 6 112347330-112351294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "testis: 1.6" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 15.7" "Group enriched" "Detected in some" 7 "liver cancer: 0.6;testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 1.9;RPTEC TERT1: 2.3;U-266/70: 1.0;U-266/84: 8.0" "HPA059324, HPA066464" Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA059324: , HPA066464: " "unprognostic (4.26e-1)" "unprognostic (1.45e-1)" "unprognostic (6.66e-2)" "unprognostic (3.78e-1)" "unprognostic (2.80e-3)" "unprognostic (3.73e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 RIPPLY3 DSCR6 ENSG00000183145 "Ripply transcriptional repressor 3" P57055 21 37006150-37019662 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 3.0;Extravillous trophoblasts: 2.9;Hepatic stellate cells: 1.8;Squamous epithelial cells: 1.6;Urothelial cells: 1.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.1;PC-3: 1.0;RPTEC TERT1: 1.3;RT4: 1.2;SCLC-21H: 3.9;T-47d: 3.2" "Low region specificity" "Detected in many" HPA055541 Uncertain NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA055541: AB_2682840" "unprognostic (1.77e-1)" "unprognostic (2.40e-2)" "unprognostic (3.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-3)" "unprognostic (2.19e-2)" "unprognostic (3.08e-1)" "unprognostic (1.91e-2)" "unprognostic (2.11e-2)" "unprognostic (2.17e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-2)" "unprognostic (3.58e-1)" "unprognostic (2.31e-1)" "unprognostic (1.57e-4)" "unprognostic (2.69e-1)" 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 3.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 1.3 1.2 3.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 1.2 0.0 0.4 1.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.8 0.2 3.0 0.0 0.2 0.0 2.9 0.4 0.0 0.6 0.0 0.2 1.8 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.4 0.4 1.6 0.4 0.0 0.0 0.2 0.1 1.4 RTN2 "NSP2, NSPL1, SPG12" ENSG00000125744 "Reticulon 2" O75298 19 45485294-45497055 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 509.8;tongue: 207.7" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.3;Extravillous trophoblasts: 145.7;Skeletal myocytes: 73.2;Syncytiotrophoblasts: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.2;eosinophil: 2.6;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "dendritic cells: 1.6;granulocytes: 6.2" "Cell line enhanced" "Detected in many" "RH-30: 44.3;RT4: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034941, HPA034948" Approved Approved "Nuclear speckles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear speckles" "HPA034941: AB_10671358, HPA034948: AB_2674375" "unprognostic (3.08e-1)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (5.07e-3)" "unprognostic (1.76e-1)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.89e-2)" "unprognostic (3.09e-1)" "unprognostic (6.44e-2)" "unprognostic (5.10e-3)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.58e-6)" "unprognostic (4.34e-1)" "unprognostic (3.23e-1)" "unprognostic (2.21e-1)" "unprognostic (2.03e-1)" 9.9 13.6 21.4 3.4 25.7 1.7 12.0 15.9 43.6 5.9 7.8 21.8 2.8 15.2 2.5 12.1 4.6 7.9 21.9 24.7 22.0 7.1 3.9 8.2 4.7 27.3 19.3 1.9 4.8 10.1 7.6 19.2 27.0 17.0 2.2 5.7 22.3 10.6 509.8 9.1 8.7 7.3 14.1 11.2 7.9 1.6 25.1 1.1 4.9 207.7 2.0 12.4 7.8 29.0 3.8 5.2 8.6 6.7 14.4 17.6 16.9 8.5 20.0 5.2 9.9 10.4 3.2 3.3 11.4 9.3 4.2 7.2 5.6 4.1 1.7 7.9 8.2 23.0 3.9 7.8 6.2 1.4 25.0 19.5 2.2 2.3 4.2 9.2 9.6 0.9 12.9 6.2 15.6 2.9 0.0 4.3 6.3 17.0 6.8 3.6 44.3 18.8 3.0 45.0 24.1 23.1 1.7 40.7 13.2 8.0 32.3 9.1 8.6 14.7 4.4 0.4 1.9 3.5 8.7 7.7 3.9 5.2 7.7 6.2 0.1 2.6 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.3 1.6 0.0 0.2 21.4 25.7 15.9 43.6 24.7 22.0 27.3 19.3 27.0 14.1 25.1 29.0 9.8 3.2 8.1 2.6 0.8 6.4 27.7 8.9 6.8 10.4 18.4 21.1 4.6 4.3 4.6 3.7 6.2 134.3 2.9 0.9 0.0 21.3 0.3 2.1 7.0 15.3 11.4 1.7 21.0 6.8 145.7 14.0 3.1 3.4 16.5 4.2 18.9 3.1 27.3 23.5 13.3 2.2 12.2 12.9 12.0 0.4 5.6 10.7 23.2 1.9 6.5 9.1 1.0 4.5 2.1 13.1 0.3 6.8 2.5 13.0 0.3 0.3 1.3 13.6 13.1 73.2 12.3 0.5 3.9 2.3 3.4 120.1 1.0 16.4 0.7 23.2 S100A5 S100D ENSG00000196420 "S100 calcium binding protein A5" P33763 1 153537147-153541765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 3.6;thyroid gland: 5.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.7;Distal tubular cells: 3.9;Extravillous trophoblasts: 8.5;Langerhans cells: 3.1;Theca cells: 6.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 11.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.0;granulocytes: 1.4;T-cells: 4.6" "Cell line enhanced" "Detected in many" "OE19: 34.3;RPTEC TERT1: 11.9;RT4: 19.9;SCLC-21H: 17.3" "Region enriched" "Detected in many" 86 "olfactory bulb: 980.0" "Region enriched" "Detected in single" 15 "olfactory bulb: 5.6" HPA064184 Approved Nucleoplasm Yes NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA064184: AB_2685206" "unprognostic (6.09e-2)" "unprognostic (2.92e-2)" "unprognostic (8.92e-2)" "unprognostic (1.63e-5)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" "unprognostic (1.52e-3)" "unprognostic (4.11e-2)" "unprognostic (2.69e-1)" "unprognostic (7.39e-3)" "unprognostic (3.08e-2)" "unprognostic (2.20e-2)" "unprognostic (1.07e-2)" "unprognostic (9.53e-2)" "unprognostic (5.70e-2)" "unprognostic (4.68e-3)" 0.2 0.1 0.3 0.1 0.3 0.7 0.2 0.9 0.8 0.3 0.1 0.2 1.5 0.6 0.1 0.9 0.5 1.0 0.1 0.3 0.4 2.9 0.0 0.5 1.5 0.4 0.3 0.1 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.2 0.0 0.1 3.6 0.3 0.0 0.3 0.4 1.2 0.1 0.4 0.7 5.2 0.1 0.4 1.1 0.3 0.4 2.2 5.7 0.0 0.0 0.6 0.4 0.4 1.0 1.3 0.7 1.4 0.6 4.2 0.0 3.7 2.1 0.4 1.7 0.1 1.0 0.9 0.5 0.0 2.7 2.6 0.2 0.4 0.0 3.5 0.0 1.1 2.7 0.8 0.5 0.5 0.0 0.7 0.2 3.0 0.2 0.5 1.3 0.2 34.3 9.7 0.0 1.8 1.1 11.9 19.9 17.3 0.0 0.2 9.0 0.8 1.5 0.0 0.5 0.4 0.1 1.3 2.6 1.7 0.0 0.9 0.0 0.5 0.7 0.4 0.0 0.7 1.4 1.2 0.1 4.6 0.5 2.6 1.3 1.8 0.3 1.4 0.6 1.2 0.0 0.4 3.0 3.9 0.7 0.3 0.3 0.9 0.8 0.3 0.4 0.4 0.3 0.5 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.2 3.7 0.0 0.1 0.2 0.1 3.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 8.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.0 0.6 3.1 0.0 0.3 0.5 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 1.2 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.6 6.8 0.3 0.6 SCO1 SCOD1 ENSG00000133028 "Synthesis of cytochrome C oxidase 1" O75880 17 10672474-10698375 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021565, HPA021579" Enhanced NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA021565: AB_1856631, HPA021579: AB_1856632" "unprognostic (6.11e-3)" "unprognostic (2.88e-1)" "unprognostic (5.12e-3)" "unprognostic (1.09e-2)" "unprognostic (1.92e-2)" "unprognostic (7.52e-2)" "unprognostic (5.01e-2)" "unprognostic (3.02e-2)" "unprognostic (7.09e-3)" "unprognostic (1.83e-2)" "unprognostic (2.43e-3)" "unprognostic (3.84e-2)" "prognostic favorable (9.69e-7)" "unprognostic (4.94e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.12e-2)" 16.4 18.5 9.2 12.2 9.4 8.9 14.2 9.7 9.5 12.5 14.5 18.8 19.9 13.6 8.0 16.5 10.6 8.0 24.2 9.2 10.1 20.0 30.1 10.2 12.0 9.7 9.4 10.4 9.6 15.7 12.5 11.3 9.7 12.8 14.6 9.2 11.9 9.7 24.9 12.1 16.8 9.2 9.6 12.0 13.2 12.0 10.0 9.6 13.1 17.2 9.9 13.5 12.3 10.2 32.6 46.9 19.0 25.5 22.8 19.4 40.7 35.2 18.3 31.1 29.9 24.0 18.5 56.8 37.4 31.6 19.1 35.0 38.0 33.4 34.7 30.1 48.4 29.3 28.8 34.0 32.5 20.5 20.8 24.7 21.4 29.3 46.3 16.2 22.5 36.9 30.3 9.8 32.4 18.4 28.7 21.1 42.0 36.6 23.9 33.8 23.6 25.4 40.3 23.2 10.1 29.2 41.6 25.4 37.2 24.4 32.1 14.4 26.9 23.7 20.2 25.6 37.1 15.5 16.5 21.6 19.3 25.5 26.3 6.6 15.5 14.8 11.5 18.5 12.2 13.2 10.0 12.0 15.2 9.8 12.2 12.8 5.1 11.1 20.5 10.9 14.3 12.2 9.2 9.4 9.7 9.5 9.2 10.1 9.7 9.4 9.7 9.6 10.0 10.2 18.1 22.4 19.8 5.9 24.3 11.5 23.3 32.2 13.1 20.4 14.0 13.2 39.5 18.6 23.4 18.4 66.7 61.0 15.5 34.6 41.1 26.1 4.0 13.7 25.2 19.1 15.7 22.1 4.2 20.4 102.6 19.7 24.5 15.9 8.8 22.4 19.6 38.2 29.8 16.8 4.7 25.3 26.4 18.9 9.5 5.4 18.6 15.9 10.6 6.5 28.4 20.7 22.6 2.5 5.4 24.1 19.3 19.2 18.4 33.1 31.6 49.8 16.1 37.7 6.6 23.8 19.1 28.4 37.0 21.5 11.8 60.5 17.5 43.0 35.6 23.0 SEMA4C "Semacl1, Semaf, SEMAI" ENSG00000168758 "Semaphorin 4C" Q9C0C4 2 96859718-96870757 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 137.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "BEWO: 298.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011090 Approved NA NA 700000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA011090: AB_2185705" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (7.10e-2)" "unprognostic (4.46e-2)" "unprognostic (1.57e-2)" "unprognostic (4.20e-3)" "unprognostic (3.08e-1)" "unprognostic (2.16e-1)" "unprognostic (3.56e-2)" "unprognostic (1.82e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (9.50e-7)" "unprognostic (4.78e-3)" "unprognostic (3.09e-1)" "unprognostic (7.31e-2)" "unprognostic (4.08e-1)" 21.3 8.9 11.5 11.3 24.2 3.0 17.7 16.8 19.9 29.0 0.5 42.1 7.4 37.2 6.0 14.0 33.3 15.3 20.2 11.8 15.6 14.9 13.3 14.4 9.8 24.9 21.1 23.1 9.4 7.1 10.2 41.8 21.0 20.8 5.7 7.0 16.5 20.6 7.5 15.9 14.6 19.3 18.7 28.5 15.1 2.7 19.0 6.5 12.3 13.4 5.3 32.3 22.3 39.1 8.0 11.7 35.6 39.7 8.4 10.5 298.5 13.9 17.4 13.4 13.5 11.8 13.3 0.0 22.3 8.5 13.3 8.1 10.2 6.9 6.5 15.2 11.8 5.4 10.5 22.2 19.2 2.2 13.7 16.1 5.4 12.3 10.4 14.9 9.9 2.6 36.5 11.6 12.7 41.0 0.1 17.4 49.1 0.4 10.6 12.5 20.0 13.8 4.8 17.1 22.4 32.4 11.2 24.6 60.8 27.6 8.7 21.4 3.1 21.9 27.3 30.9 14.6 0.2 1.0 0.1 10.6 17.2 37.1 0.5 0.0 0.0 0.6 0.2 0.8 0.0 0.2 0.4 0.0 0.0 0.4 0.1 0.0 1.4 1.5 0.8 0.3 0.4 11.5 24.2 16.8 19.9 11.8 15.6 24.9 21.1 21.0 18.7 19.0 39.1 28.1 0.0 10.3 15.3 1.1 11.5 7.9 7.6 18.2 32.2 9.9 8.3 6.9 12.8 8.6 5.5 10.4 46.8 9.7 1.8 1.9 9.7 0.5 7.4 15.8 26.6 5.4 2.1 7.2 5.0 137.3 17.3 3.1 11.6 1.3 10.2 23.9 9.8 7.9 15.2 4.1 5.7 6.1 4.4 6.1 1.5 13.4 9.2 21.4 18.7 3.2 23.6 12.3 4.5 35.5 10.5 1.2 9.1 3.6 9.4 0.1 0.8 7.4 38.8 19.7 11.4 24.1 0.6 4.2 13.0 10.2 45.0 9.5 4.9 3.9 4.8 SEPTIN14 "FLJ44060, SEPT14" ENSG00000154997 "Septin 14" Q6ZU15 7 55793540-55862755 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 22.5" "Cell type enriched" "Detected in single" 5 "Extravillous trophoblasts: 1.1" "Cancer enriched" "Detected in some" 10 "glioma: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 6.2;U-266/84: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA073255 Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA073255: AB_2686590" "unprognostic (1.29e-1)" "unprognostic (3.50e-1)" "unprognostic (1.98e-2)" "unprognostic (1.57e-1)" 0.9 0.6 1.0 1.4 1.0 2.3 0.9 1.3 1.3 0.7 0.1 0.6 0.5 1.0 1.0 0.7 0.7 0.9 0.6 0.9 1.0 1.1 2.3 0.7 1.0 0.8 0.6 1.1 0.6 1.1 1.3 1.1 1.0 1.2 0.7 2.0 0.8 0.5 0.6 1.4 0.5 0.7 0.3 1.2 0.9 22.5 1.0 1.2 1.2 0.6 0.8 0.8 0.0 1.1 1.2 0.3 1.3 2.9 1.3 1.0 6.2 0.8 0.7 0.6 0.9 0.2 0.8 0.9 0.2 0.5 1.3 1.1 1.4 1.0 1.7 1.6 0.7 0.6 2.3 2.3 2.8 1.3 1.4 1.1 1.8 0.8 1.5 1.2 0.7 2.2 2.3 1.3 1.0 0.6 1.8 1.7 1.1 2.0 0.2 0.7 1.2 1.4 1.0 0.9 1.0 1.3 0.3 0.7 1.2 1.4 0.8 1.8 0.6 0.8 0.8 0.9 0.6 1.7 5.7 1.3 0.7 4.6 1.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 1.0 1.0 1.3 1.3 0.9 1.0 0.8 0.6 1.0 0.3 1.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969475-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 233.7" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 27.9" "Group enriched" "Detected in many" 5 "glioma: 24.6;melanoma: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.6;Daudi: 22.3;SCLC-21H: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" "Actin filaments" "CAB017633: AB_2301476, HPA003548: AB_1079908" "unprognostic (2.10e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (2.37e-1)" "unprognostic (2.67e-3)" "unprognostic (3.09e-2)" "unprognostic (1.30e-2)" "unprognostic (6.30e-2)" "unprognostic (2.51e-2)" "unprognostic (9.15e-2)" "unprognostic (6.68e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" 0.2 4.6 134.7 0.4 160.5 0.1 1.3 82.4 233.7 0.2 30.5 0.8 0.3 0.2 1.4 0.2 0.1 0.4 0.2 167.0 89.5 0.3 0.1 0.7 0.5 86.2 73.4 0.2 1.2 18.6 7.8 5.7 83.8 1.3 0.5 28.4 0.4 0.0 0.1 1.6 0.4 0.3 56.9 0.2 0.7 2.1 91.4 0.9 0.8 0.2 0.5 0.3 0.4 150.7 1.5 1.7 26.6 20.1 0.3 0.0 13.3 0.3 0.3 1.8 0.8 0.4 3.1 22.3 0.7 0.2 11.4 0.1 14.0 0.1 0.7 9.2 4.6 0.1 0.5 0.0 0.2 0.0 0.9 0.2 1.0 0.1 0.0 0.0 0.0 12.1 0.0 3.4 0.0 2.4 3.7 0.2 18.2 0.2 0.7 17.9 0.0 1.3 0.0 2.7 71.4 14.8 10.9 0.1 18.2 2.5 2.6 6.7 0.0 0.0 9.2 0.9 1.0 14.1 13.1 0.2 0.3 9.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 134.7 160.5 82.4 233.7 167.0 89.5 86.2 73.4 83.8 56.9 91.4 150.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 SERTAD4 DJ667H12.2 ENSG00000082497 "SERTA domain containing 4" Q9NUC0 1 210232796-210246631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 28.5;Breast glandular cells: 23.1;Extravillous trophoblasts: 54.9;Ionocytes: 24.4;Squamous epithelial cells: 27.4" "Cancer enhanced" "Detected in many" "breast cancer: 10.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 7.5;BEWO: 7.4;SCLC-21H: 7.4;SK-BR-3: 8.5;T-47d: 10.5;U-2 OS: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027344, HPA028514" Uncertain Supported Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA027344: AB_10601770, HPA028514: AB_10611391" "unprognostic (1.75e-2)" "unprognostic (3.92e-2)" "unprognostic (3.83e-2)" "unprognostic (9.74e-2)" "unprognostic (1.98e-2)" "unprognostic (1.27e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-1)" "unprognostic (7.74e-2)" "unprognostic (8.49e-2)" "unprognostic (1.69e-2)" "unprognostic (5.98e-2)" "unprognostic (6.24e-2)" "unprognostic (2.05e-1)" "unprognostic (3.85e-2)" "unprognostic (6.55e-2)" "unprognostic (4.24e-1)" 1.1 0.3 0.6 0.3 1.6 0.0 3.6 1.0 1.1 2.0 0.2 4.8 0.4 3.8 0.6 4.2 1.7 0.7 3.0 0.6 1.0 1.9 0.0 1.5 0.1 0.9 1.4 1.0 0.1 0.6 0.9 1.0 1.0 1.8 1.4 0.1 5.9 1.4 0.2 3.3 0.8 2.7 1.2 0.1 1.4 0.2 0.8 0.6 1.4 0.7 0.7 0.6 1.8 1.1 7.5 0.1 1.6 0.0 0.8 0.7 7.4 1.8 1.8 1.4 2.4 0.3 0.8 0.0 0.2 0.4 1.1 3.6 0.2 0.6 0.7 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 1.7 0.2 0.0 0.0 0.0 0.3 1.8 0.0 0.0 5.2 6.0 0.3 0.0 2.4 0.0 1.2 1.3 7.4 6.3 1.2 8.5 0.1 2.9 10.5 0.0 2.3 2.0 8.7 0.1 5.6 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.6 1.0 1.1 0.6 1.0 0.9 1.4 1.0 1.2 0.8 1.1 5.0 6.4 3.9 1.6 0.0 16.7 9.6 16.0 28.5 2.5 23.1 9.3 0.7 1.5 10.9 9.2 0.0 14.2 0.0 1.5 7.9 2.1 0.5 4.8 1.2 5.2 1.2 0.0 10.1 3.9 54.9 7.5 2.6 5.8 0.0 9.3 2.5 0.0 1.4 0.0 3.7 5.6 24.4 0.0 5.0 0.6 0.6 0.3 10.6 3.7 0.0 0.5 0.0 1.0 9.4 8.1 1.3 1.5 0.0 2.5 0.0 0.4 13.9 0.3 0.0 1.8 3.7 0.1 1.7 27.4 4.7 4.4 0.3 0.1 6.5 3.4 SH3GL1 "CNSA1, EEN, MGC111371, SH3D2B, SH3P8" ENSG00000141985 "SH3 domain containing GRB2 like 1, endophilin A2" Q99961 19 4360370-4400547 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021485 Approved Enhanced Cytosol NA NA 390000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA021485: AB_1856816" "unprognostic (1.32e-1)" "prognostic favorable (1.50e-4)" "unprognostic (6.85e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.84e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.36e-8)" "unprognostic (5.48e-3)" "unprognostic (2.45e-1)" "unprognostic (1.02e-3)" "unprognostic (4.10e-2)" 61.1 64.7 25.0 29.4 28.8 54.4 50.0 32.8 38.1 69.8 24.2 41.3 40.9 45.1 8.2 175.8 43.9 25.4 37.6 34.4 20.5 39.2 57.4 43.8 22.8 24.8 22.5 49.0 41.8 10.8 46.8 38.9 23.8 48.8 9.2 7.0 51.8 24.0 21.2 119.8 43.7 20.8 21.1 46.8 35.9 28.1 24.7 16.8 37.1 10.1 19.8 53.0 91.6 28.0 111.3 49.2 50.0 66.8 57.4 89.0 92.2 94.2 80.3 82.2 81.1 77.4 56.8 24.9 39.0 94.1 39.8 89.5 35.6 103.7 21.9 33.1 59.8 30.0 66.5 102.7 82.6 27.2 32.6 75.0 70.9 69.4 42.4 40.6 97.8 23.7 78.9 55.1 67.1 92.6 26.5 28.4 126.0 40.4 54.3 20.8 69.8 43.6 65.8 96.4 49.1 75.7 83.3 81.9 59.3 23.5 56.5 42.5 149.3 78.6 57.1 166.7 97.2 34.8 23.2 26.7 112.9 70.0 110.4 0.8 2.3 3.1 2.7 1.1 2.6 3.7 4.0 3.9 3.0 2.7 2.2 2.5 5.6 2.3 3.4 3.8 4.1 2.3 25.0 28.8 32.8 38.1 34.4 20.5 24.8 22.5 23.8 21.1 24.7 28.0 31.6 9.6 21.5 11.8 15.2 60.8 41.0 43.2 19.4 17.1 17.1 15.7 3.6 11.5 25.1 9.2 6.2 41.2 14.7 23.6 13.7 32.1 7.2 17.9 33.8 30.7 10.2 30.7 23.4 29.3 153.7 37.5 19.9 29.5 9.5 23.4 32.9 27.3 51.5 10.1 14.0 18.6 20.3 19.4 51.8 6.7 32.6 22.3 23.2 14.0 14.7 20.3 15.5 12.5 10.3 50.4 17.0 24.0 16.4 38.0 61.6 22.9 15.4 8.7 13.1 17.2 29.3 15.7 11.5 36.8 85.8 44.2 15.1 50.1 19.8 67.1 SKP2 "FBL1, FBXL1, p45" ENSG00000145604 "S-phase kinase associated protein 2" Q13309 5 36151989-36196849 "Cancer-related genes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 37.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.4;Extravillous trophoblasts: 227.3;Syncytiotrophoblasts: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 274.7;RH-30: 286.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013491, CAB013533, HPA051196, HPA054633" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "CAB013491: AB_2533074, CAB013533: , HPA051196: AB_2681383, HPA054633: AB_2682550" "unprognostic (2.32e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" "unprognostic (5.74e-2)" "unprognostic (9.56e-2)" "unprognostic (1.52e-2)" "unprognostic (1.21e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.72e-7)" "prognostic favorable (8.57e-4)" "unprognostic (5.06e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (4.77e-15)" "unprognostic (2.50e-2)" "unprognostic (3.73e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-1)" 4.9 4.0 3.6 5.8 3.9 11.4 4.9 4.7 4.5 5.9 3.9 6.1 6.3 4.7 4.3 8.3 5.1 2.9 2.5 3.9 3.1 2.3 9.8 4.2 7.9 3.7 3.5 5.2 3.8 2.5 4.0 37.9 3.9 4.0 6.1 4.6 4.0 3.7 2.2 5.7 6.5 4.1 3.9 5.9 4.0 2.6 3.7 12.3 3.1 1.6 8.3 4.7 5.6 5.4 25.4 14.8 35.6 54.3 15.5 20.1 274.7 31.2 25.7 89.5 48.7 83.3 22.8 43.3 10.6 20.0 13.3 28.3 53.3 46.7 71.0 19.2 46.7 23.9 51.4 47.1 6.1 44.8 11.4 18.1 12.2 16.9 8.5 7.7 24.2 40.2 37.9 9.1 31.9 16.4 58.9 26.8 51.5 23.8 24.2 53.7 286.7 28.3 7.2 28.1 45.5 46.8 94.3 27.4 14.1 32.2 22.7 33.3 8.0 31.4 36.1 13.5 24.5 12.4 13.1 50.8 15.2 61.3 21.9 9.2 6.6 13.4 4.2 6.1 6.9 5.2 4.7 4.5 14.0 6.0 6.4 4.6 1.1 6.2 3.2 3.5 4.8 4.7 3.6 3.9 4.7 4.5 3.9 3.1 3.7 3.5 3.9 3.9 3.7 5.4 4.4 22.4 8.9 11.8 8.7 3.7 2.4 7.1 12.0 8.2 3.6 4.2 1.3 1.5 1.7 1.8 10.4 134.4 7.4 2.4 1.9 2.4 0.7 5.2 6.5 6.5 3.0 14.1 22.4 2.9 227.3 11.6 7.1 2.4 2.5 20.9 1.8 11.9 35.0 0.0 13.1 6.0 4.1 9.3 3.1 0.3 4.1 5.3 1.8 12.2 7.6 2.5 9.2 11.6 29.5 2.6 3.4 6.4 10.9 1.0 3.2 1.4 6.2 6.8 0.0 11.5 4.1 1.4 6.4 19.8 4.0 83.9 5.6 11.8 9.6 1.2 SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 198.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1667.1;Syncytiotrophoblasts: 748.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 109.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 260000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "Nuclear membrane" "CAB017490: AB_2189333, HPA021451: AB_1853663" "unprognostic (2.49e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-3)" "unprognostic (4.26e-3)" "prognostic unfavorable (1.19e-7)" "prognostic unfavorable (2.02e-5)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (4.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.71e-7)" "unprognostic (2.27e-1)" "unprognostic (4.00e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-2)" 30.4 16.9 3.8 25.3 5.8 22.7 15.7 6.6 9.7 26.2 5.0 28.9 11.6 11.6 1.3 42.4 18.5 12.8 26.0 4.5 7.3 48.2 11.3 46.4 5.7 17.3 8.5 9.1 5.8 2.5 12.1 24.7 11.9 19.6 5.7 5.7 27.5 5.9 198.3 8.4 22.9 6.0 8.4 57.5 22.0 32.0 13.8 2.9 29.1 73.2 5.2 26.3 28.5 15.1 52.8 24.4 0.6 1.3 7.8 28.8 51.7 225.6 107.7 117.4 142.2 10.1 119.1 0.7 158.0 122.5 127.9 18.9 15.6 242.0 51.8 78.1 1.2 87.4 144.0 236.4 164.1 105.2 111.5 64.8 38.2 77.0 38.5 185.8 69.1 2.2 1.0 26.6 116.1 14.0 1.4 166.3 1.9 22.1 223.5 0.9 1.6 33.2 75.9 3.0 2.9 1.7 196.7 166.9 3.2 20.4 25.4 131.4 124.0 281.7 5.1 4.5 200.9 97.3 1.9 3.9 140.2 94.7 3.0 56.6 32.6 92.1 9.6 30.4 13.4 8.1 7.7 10.5 24.1 6.2 4.2 5.3 109.1 25.3 31.4 15.2 7.3 16.0 3.8 5.8 6.6 9.7 4.5 7.3 17.3 8.5 11.9 8.4 13.8 15.1 19.2 9.6 9.8 3.6 27.9 6.5 47.5 210.1 2.8 13.4 3.2 2.5 6.1 4.3 182.3 57.0 4.2 67.6 72.4 216.7 0.0 136.1 3.0 33.7 15.4 29.9 20.9 9.1 0.3 18.0 1667.1 17.2 45.3 65.1 75.0 15.9 16.8 1.1 271.0 127.9 0.3 28.3 148.5 99.9 84.6 3.8 3.1 168.6 14.2 9.4 184.9 20.3 40.2 0.0 1.0 305.5 190.2 3.8 35.7 16.5 62.4 5.6 91.1 11.6 0.0 1.6 50.5 1.9 9.5 1.6 6.7 748.8 38.5 0.8 33.4 119.6 SLC25A15 "D13S327, HHH, ORC1, ORNT1" ENSG00000102743 "Solute carrier family 25 member 15" Q9Y619 13 40789412-40812460 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 37.6;liver: 88.3;pancreas: 52.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.5;Hepatocytes: 39.8;Proximal enterocytes: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042146 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA042146: AB_2677874" "unprognostic (4.17e-1)" "unprognostic (4.50e-2)" "unprognostic (2.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.85e-1)" "prognostic favorable (2.16e-4)" "unprognostic (2.34e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (2.37e-2)" "prognostic favorable (1.74e-4)" "unprognostic (4.04e-3)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (5.46e-4)" 2.3 1.4 2.0 4.1 2.2 5.6 4.6 2.3 2.5 2.1 2.3 5.9 37.6 3.1 1.1 3.2 2.6 5.0 2.8 1.9 2.6 5.6 88.3 2.3 4.8 2.6 2.3 2.9 52.1 3.4 1.3 2.8 2.5 2.8 6.5 2.8 3.4 1.8 5.9 3.7 26.7 3.4 2.1 2.5 5.5 9.4 2.4 5.3 17.3 6.0 5.3 2.6 1.6 2.9 7.4 14.7 16.5 21.3 6.5 8.2 17.3 5.6 2.9 6.8 3.9 17.6 15.2 48.0 6.4 10.3 12.7 12.6 26.6 15.5 7.0 11.9 12.4 37.0 8.6 26.6 12.7 15.0 5.3 9.0 8.6 9.6 21.9 4.6 11.2 23.8 18.1 7.8 11.8 28.2 10.2 9.9 33.2 32.7 7.9 25.5 12.0 10.6 11.7 7.0 7.7 20.1 10.2 18.4 10.1 11.5 13.6 23.2 8.4 8.4 12.1 12.7 17.0 8.9 9.6 27.9 8.4 11.4 16.4 1.3 0.5 0.1 1.6 0.9 1.0 0.6 1.0 1.1 1.1 0.7 1.0 2.0 0.7 1.4 0.5 0.5 0.9 0.5 2.0 2.2 2.3 2.5 1.9 2.6 2.6 2.3 2.5 2.1 2.4 2.9 0.3 3.2 0.5 3.9 1.3 0.3 1.0 0.8 2.2 1.4 2.1 1.4 1.1 1.5 0.2 0.0 0.0 2.2 1.3 0.6 7.9 2.1 4.6 1.2 2.1 0.9 1.2 9.0 2.4 4.3 44.5 1.0 1.5 2.1 0.0 1.5 0.7 39.8 1.7 0.0 4.3 0.6 2.0 1.6 0.3 6.8 0.6 1.0 1.8 1.0 0.0 0.4 2.1 5.0 1.4 1.7 2.7 0.0 6.2 1.6 19.0 4.3 0.1 1.9 0.0 1.0 1.1 5.4 9.3 2.1 0.1 1.5 3.2 4.3 3.5 0.8 SLC29A1 ENT1 ENSG00000112759 "Solute carrier family 29 member 1 (Augustine blood group)" Q99808 6 44219553-44234142 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 216.6;Extravillous trophoblasts: 224.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 26 "eosinophil: 1046.6" "Lineage enriched" "Detected in all" 26 "granulocytes: 1046.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012384 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA012384: AB_1857073" "unprognostic (1.82e-2)" "unprognostic (1.41e-2)" "unprognostic (1.81e-1)" "unprognostic (2.49e-3)" "unprognostic (2.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (1.38e-2)" "unprognostic (4.60e-2)" "unprognostic (9.02e-2)" "unprognostic (1.34e-1)" 76.4 95.8 10.2 22.3 10.2 53.4 50.4 13.0 14.8 25.4 4.5 59.7 13.1 37.3 15.9 25.3 34.5 44.2 119.7 10.1 12.2 17.8 57.9 33.1 25.9 13.2 10.2 12.9 91.2 22.8 22.6 58.8 15.3 16.5 17.8 21.1 35.6 19.3 144.5 53.0 17.2 46.2 9.5 14.5 53.7 14.9 10.7 81.3 30.7 100.7 17.0 32.8 17.7 10.8 85.3 84.2 58.5 95.1 87.8 8.1 347.1 61.2 24.0 83.6 57.4 91.8 34.8 171.2 60.8 18.5 51.7 103.8 105.2 72.8 51.9 97.6 97.2 150.5 57.8 122.5 14.1 170.3 139.7 10.9 18.4 123.0 42.7 171.6 216.0 137.2 205.4 100.1 46.9 94.0 142.0 114.4 89.0 218.4 55.4 94.0 117.8 208.9 49.1 49.5 75.0 97.0 18.4 58.9 43.9 61.5 80.7 107.1 333.1 46.4 74.8 62.6 117.7 67.0 93.8 221.9 28.8 136.8 57.1 21.9 12.1 1046.6 5.1 38.8 4.2 4.4 2.7 3.9 6.8 2.4 1.1 2.4 1.8 3.1 32.5 40.0 8.2 6.6 10.2 10.2 13.0 14.8 10.1 12.2 13.2 10.2 15.3 9.5 10.7 10.8 64.2 0.0 10.5 1.3 4.0 10.7 9.0 4.1 2.2 10.9 20.2 30.1 46.4 17.2 6.0 7.3 14.6 216.6 5.7 3.0 3.9 24.2 0.5 4.3 3.5 31.7 31.2 49.2 18.4 56.7 224.6 40.0 26.5 11.2 8.2 25.4 25.7 16.7 63.6 5.0 25.4 2.9 79.3 37.0 13.3 2.8 32.9 19.2 35.6 16.9 8.3 4.3 0.0 5.0 2.6 61.9 3.4 53.8 14.2 18.2 0.7 0.9 6.9 11.9 92.1 21.0 22.5 0.4 11.0 4.6 15.6 42.0 3.2 4.1 6.2 9.8 SLC30A5 "FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1" ENSG00000145740 "Solute carrier family 30 member 5" Q8TAD4 5 69093949-69131069 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035373 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Nucleoplasm "HPA035373: AB_10794630" "unprognostic (9.81e-3)" "unprognostic (3.33e-1)" "unprognostic (2.82e-2)" "unprognostic (8.16e-2)" "unprognostic (1.65e-1)" "unprognostic (3.88e-2)" "unprognostic (1.16e-3)" "unprognostic (2.47e-2)" "unprognostic (4.65e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (2.92e-1)" "unprognostic (1.49e-1)" "unprognostic (2.53e-2)" "unprognostic (2.07e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" 25.8 25.6 9.8 21.0 10.3 19.6 30.3 11.7 15.9 29.7 17.4 26.9 24.7 25.6 38.2 19.3 24.3 24.0 24.1 9.7 10.6 29.1 29.0 21.1 24.7 10.1 11.4 22.3 33.0 35.9 24.0 27.4 10.2 29.4 24.7 18.5 30.8 24.0 16.4 27.1 23.6 22.8 9.7 21.9 26.3 16.4 10.9 20.8 37.5 16.5 23.7 23.6 19.7 12.1 37.4 29.9 26.3 46.2 69.1 53.2 82.5 58.8 53.6 36.4 55.1 26.0 45.7 50.2 70.6 41.4 63.7 38.8 38.6 46.1 61.5 60.2 43.5 55.7 35.0 43.2 55.0 34.8 58.3 35.7 57.1 38.3 46.5 50.1 36.6 34.2 34.9 57.0 46.1 46.9 46.4 71.6 29.4 25.3 33.3 35.5 33.2 89.9 53.6 34.5 46.0 36.8 47.4 45.0 84.5 36.0 43.7 76.2 33.3 23.2 29.5 58.7 58.2 49.5 67.5 37.9 46.6 62.3 58.9 11.9 5.1 8.5 4.1 5.3 4.4 6.9 6.4 6.2 6.3 4.3 5.9 4.8 4.1 4.0 5.5 9.6 4.9 2.8 9.8 10.3 11.7 15.9 9.7 10.6 10.1 11.4 10.2 9.7 10.9 12.1 17.3 19.2 21.5 14.7 26.9 18.7 27.9 27.5 19.9 15.3 28.5 20.6 29.2 18.6 23.2 25.8 22.9 42.0 35.3 19.9 29.4 22.0 6.9 28.8 35.8 19.3 13.2 29.9 29.6 27.1 80.4 24.8 34.7 23.7 41.3 15.4 21.8 19.8 22.3 8.4 30.6 27.9 32.6 17.2 18.4 9.9 24.2 16.8 14.2 19.7 21.2 14.9 15.5 22.1 23.3 19.0 16.7 22.2 51.8 34.7 16.9 21.3 27.7 24.7 26.3 17.5 21.4 11.0 14.9 26.6 21.5 51.6 23.4 20.9 23.2 28.6 SLC44A2 CTL2 ENSG00000129353 "Solute carrier family 44 member 2" Q8IWA5 19 10602457-10644557 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 171.1;Extravillous trophoblasts: 257.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 333.2;SK-BR-3: 306.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003228, HPA070799" Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cell Junctions" "HPA003228: AB_1080009, HPA070799: AB_2686314" "unprognostic (6.35e-3)" "unprognostic (5.75e-2)" "unprognostic (4.34e-1)" "unprognostic (3.06e-3)" "unprognostic (4.38e-2)" "unprognostic (8.41e-3)" "unprognostic (1.64e-1)" "unprognostic (2.52e-1)" "unprognostic (2.66e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.63e-2)" "prognostic favorable (1.71e-5)" "unprognostic (1.28e-1)" "unprognostic (1.67e-1)" "unprognostic (8.21e-3)" "unprognostic (3.61e-2)" 74.7 33.2 69.6 43.9 85.0 65.0 72.7 78.4 67.4 64.6 33.4 58.3 26.7 43.0 36.2 81.6 59.0 55.8 71.4 62.7 69.7 68.7 17.8 98.5 75.3 99.6 76.5 32.3 41.2 48.7 20.5 157.5 87.0 43.8 49.5 29.1 55.5 65.8 141.2 78.3 50.8 43.6 84.3 115.5 112.9 82.5 79.1 48.8 64.9 92.4 77.7 56.3 69.2 97.6 333.2 8.3 70.0 42.1 103.9 63.5 201.1 69.6 169.5 112.3 131.6 75.6 154.9 65.6 91.1 193.9 13.6 254.1 10.7 53.2 71.6 1.7 9.3 42.0 39.3 3.1 115.0 0.6 33.9 69.2 69.8 42.3 37.2 91.0 86.8 30.2 20.2 10.8 172.6 243.6 35.1 32.1 24.9 96.9 29.3 74.1 102.7 2.9 37.1 171.8 6.9 42.0 56.7 306.1 7.7 73.8 123.0 3.2 79.8 50.1 18.4 60.5 18.0 4.0 7.9 64.8 12.5 29.1 57.3 146.3 39.4 227.9 114.1 113.0 90.4 92.1 78.5 87.4 20.7 94.8 83.3 87.1 482.8 79.2 278.3 100.4 95.7 147.4 69.6 85.0 78.4 67.4 62.7 69.7 99.6 76.5 87.0 84.3 79.1 97.6 84.0 54.5 29.1 32.3 53.4 9.7 17.3 17.2 13.1 12.3 45.8 29.1 38.6 28.6 47.7 92.0 14.6 137.8 51.9 49.9 1.9 44.1 171.1 15.8 31.4 52.7 9.6 45.0 14.3 44.3 257.0 22.6 84.6 38.6 20.3 7.1 75.7 1.9 37.0 3.3 15.5 17.7 14.2 38.7 3.9 35.1 38.8 22.8 5.4 15.9 10.2 36.4 88.6 18.6 18.4 41.1 31.9 56.4 18.9 9.8 20.1 3.7 19.0 3.0 59.2 26.3 29.4 3.2 2.9 33.5 8.5 93.4 41.2 6.8 23.4 20.6 SLCO4A1 "OATP-E, OATP4A1, SLC21A12" ENSG00000101187 "Solute carrier organic anion transporter family member 4A1" Q96BD0 20 62642503-62685785 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 57.2" "Cell type enhanced" "Detected in many" "Adipocytes: 61.8;Extravillous trophoblasts: 239.4;Melanocytes: 60.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 197.2;RPTEC TERT1: 193.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.7" "Low region specificity" "Detected in some" "HPA030669, HPA030670" Uncertain Supported "Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Cell Junctions" "HPA030669: AB_10601163, HPA030670: AB_10670033" "unprognostic (8.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.41e-1)" "unprognostic (2.46e-3)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "unprognostic (2.84e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (3.49e-3)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (2.84e-3)" "unprognostic (9.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.25e-1)" 32.4 5.6 26.2 1.8 24.0 1.3 23.4 24.2 35.7 11.1 19.6 9.8 1.2 8.7 0.3 16.7 13.1 1.8 48.6 23.9 25.4 35.8 5.0 57.2 2.4 26.5 24.8 6.5 4.9 3.8 2.9 4.7 28.0 5.9 1.8 21.5 8.5 1.0 18.8 25.6 9.2 0.8 25.7 6.6 13.5 2.1 31.6 1.1 8.6 5.6 3.2 12.0 16.8 24.9 14.8 19.1 0.8 10.8 2.5 2.1 26.5 4.7 16.6 14.1 5.4 32.0 14.9 17.8 44.2 0.5 9.6 22.0 16.4 1.0 5.4 2.1 9.6 21.7 22.1 23.8 0.1 16.6 6.7 0.0 6.5 0.3 6.2 4.2 2.5 10.7 17.1 4.6 0.0 14.8 17.2 63.9 5.4 74.1 197.2 30.6 1.1 26.2 193.9 14.2 17.4 25.1 4.1 4.4 15.7 6.5 1.0 7.5 2.8 0.4 10.5 7.0 27.2 9.2 15.9 11.1 38.1 24.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.9 0.7 0.2 0.1 0.0 0.0 0.0 0.0 1.6 0.2 26.2 24.0 24.2 35.7 23.9 25.4 26.5 24.8 28.0 25.7 31.6 24.9 61.8 3.2 1.3 1.3 13.1 27.3 1.4 19.8 1.2 14.1 1.2 0.8 4.4 1.5 5.9 25.8 31.3 2.1 3.7 7.5 0.0 5.9 0.3 8.7 3.6 40.3 0.0 2.1 7.9 2.5 239.4 4.3 20.9 35.6 0.0 0.0 14.6 0.6 5.5 0.0 6.6 8.4 2.0 9.7 33.5 0.7 0.3 11.9 60.5 3.7 0.0 6.1 0.0 1.5 0.3 11.8 1.9 0.7 19.1 3.5 0.8 9.6 1.3 43.2 0.0 1.9 2.9 0.2 3.0 1.1 16.1 23.5 5.6 0.1 7.5 11.0 SMUG1 "FDG, HMUDG, UNG3" ENSG00000123415 "Single-strand-selective monofunctional uracil-DNA glycosylase 1" Q53HV7 12 54121277-54189008 "Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 98.9;Syncytiotrophoblasts: 100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026804, HPA065892" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA026804: , HPA065892: " "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (8.58e-2)" "unprognostic (7.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.30e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.82e-1)" "unprognostic (6.12e-2)" "prognostic favorable (1.31e-4)" "unprognostic (1.67e-3)" "unprognostic (3.35e-1)" "unprognostic (2.41e-3)" "unprognostic (2.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.46e-1)" "unprognostic (1.73e-1)" 20.5 29.2 21.9 13.9 22.4 10.7 26.3 20.7 24.2 17.3 22.6 20.8 17.1 17.1 39.9 38.6 24.5 16.9 19.4 22.3 21.1 28.9 49.6 14.7 18.9 23.7 21.4 18.8 30.0 23.9 16.9 19.1 22.1 24.0 18.7 14.3 29.7 18.1 27.4 29.4 21.3 16.3 22.1 21.8 32.2 15.9 22.7 17.8 21.9 21.8 18.6 20.3 20.1 24.8 31.9 57.5 22.2 23.2 40.4 31.3 37.7 24.2 31.4 37.2 33.8 58.0 69.5 19.0 60.4 35.1 34.8 40.3 15.7 63.7 23.5 19.7 33.3 28.6 47.4 42.3 48.2 19.3 34.0 35.7 97.7 43.9 43.2 40.4 30.2 33.3 48.2 40.3 41.4 60.8 24.3 37.2 27.7 54.3 51.7 17.5 22.6 34.3 46.6 46.2 33.1 39.2 27.6 47.3 43.5 44.9 73.7 35.9 14.3 24.7 27.5 22.5 28.1 37.3 32.1 13.1 35.8 15.0 38.4 89.6 46.2 57.1 28.5 39.5 28.4 49.7 27.3 30.7 40.3 36.6 24.6 24.6 45.5 27.1 31.5 45.5 41.0 33.9 21.9 22.4 20.7 24.2 22.3 21.1 23.7 21.4 22.1 22.1 22.7 24.8 6.6 6.4 16.0 2.9 13.3 7.5 14.4 40.2 11.4 10.5 25.5 22.5 17.7 22.8 26.4 25.8 8.4 87.5 8.8 28.4 60.7 37.1 5.2 15.3 8.9 11.0 11.5 7.4 6.8 40.2 98.9 13.6 16.3 11.0 2.5 10.1 18.2 49.4 46.1 6.7 6.1 25.8 32.6 19.2 5.8 11.8 18.6 14.0 5.4 3.7 34.0 16.3 19.6 5.0 8.1 41.4 24.6 17.7 12.6 20.7 58.4 56.6 27.1 11.9 32.9 8.5 13.8 26.2 28.0 20.8 10.4 100.0 9.5 19.4 23.7 19.6 SNRPG Sm-G ENSG00000143977 "Small nuclear ribonucleoprotein polypeptide G" P62308 2 70281362-70293740 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA064152, HPA067814" Supported Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA064152: AB_2685199, HPA067814: AB_2685903" "unprognostic (6.42e-2)" "unprognostic (7.89e-2)" "unprognostic (6.10e-2)" "unprognostic (5.42e-2)" "unprognostic (1.29e-1)" "unprognostic (1.11e-3)" "unprognostic (1.75e-3)" "unprognostic (2.28e-2)" "unprognostic (3.60e-3)" "unprognostic (6.19e-2)" "unprognostic (1.00e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (1.08e-6)" "unprognostic (4.37e-2)" "unprognostic (1.33e-1)" "unprognostic (8.96e-2)" "unprognostic (1.41e-2)" 66.9 92.0 55.9 85.9 58.0 118.0 85.1 58.4 85.7 50.4 60.2 87.9 62.1 55.2 103.0 95.5 45.6 40.5 102.2 55.3 58.3 97.1 95.5 59.8 100.7 58.9 58.0 49.2 53.1 69.5 60.4 83.8 59.5 53.7 80.3 92.7 59.2 46.0 88.3 43.5 63.2 51.6 59.1 76.6 61.1 60.1 58.4 139.9 61.2 83.8 96.9 91.4 56.3 63.1 398.0 414.3 412.2 240.0 146.5 157.1 369.0 255.4 230.5 332.8 307.2 718.7 258.1 355.1 180.6 202.2 404.9 253.9 415.1 355.7 356.7 333.2 404.5 474.0 256.6 875.4 194.0 602.3 313.6 140.2 198.1 312.8 308.8 135.0 341.5 301.1 645.3 254.8 266.9 479.0 541.5 961.8 430.4 489.9 340.2 350.4 507.9 419.0 483.9 367.1 238.1 204.4 235.9 201.1 295.8 250.7 202.1 470.1 232.9 235.3 440.2 246.3 520.4 188.1 228.3 731.8 211.1 510.0 260.9 163.1 168.5 181.1 144.2 219.2 147.4 209.1 193.4 168.8 202.5 166.0 157.8 188.9 88.1 135.8 222.4 273.0 230.1 264.8 55.9 58.0 58.4 85.7 55.3 58.3 58.9 58.0 59.5 59.1 58.4 63.1 191.7 201.9 198.9 7.2 237.0 299.1 340.3 625.6 143.4 88.8 192.3 239.1 145.7 178.7 314.8 202.3 33.3 655.3 175.7 249.1 534.1 389.6 51.0 253.2 184.7 209.1 186.6 319.4 7.4 391.5 818.7 173.3 119.3 188.4 213.3 140.7 175.3 391.8 390.8 65.6 8.7 301.5 370.2 186.6 270.8 45.4 175.8 194.0 224.1 5.6 329.1 446.1 208.1 4.5 13.8 434.1 271.6 159.1 251.9 366.1 226.5 676.1 401.8 91.4 184.1 181.3 244.4 340.7 367.4 236.6 318.2 521.5 220.2 125.9 324.1 375.1 SOWAHD ANKRD58 ENSG00000187808 "Sosondowah ankyrin repeat domain family member D" A6NJG2 X 119758588-119760202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.1;lymphoid tissue: 7.1;testis: 5.0" "Cell type enhanced" "Detected in some" "B-cells: 12.2;Extravillous trophoblasts: 38.3;Hofbauer cells: 17.5;Proximal enterocytes: 9.1;Rod photoreceptor cells: 8.2;Syncytiotrophoblasts: 9.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 4.3;NB-4: 2.9;SK-BR-3: 3.2;THP-1: 8.3;U-937: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065955 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA065955: AB_2685586" "unprognostic (1.78e-2)" "unprognostic (9.37e-2)" "unprognostic (3.10e-2)" "unprognostic (8.88e-2)" "unprognostic (1.67e-1)" "unprognostic (4.38e-2)" "unprognostic (2.03e-1)" "unprognostic (7.20e-2)" "unprognostic (3.45e-2)" "unprognostic (6.07e-2)" "unprognostic (5.80e-2)" "unprognostic (2.41e-2)" "unprognostic (1.04e-5)" "unprognostic (5.82e-2)" "unprognostic (3.14e-2)" "unprognostic (9.22e-2)" "unprognostic (3.74e-3)" 0.3 0.4 0.7 1.8 0.6 2.1 0.2 0.6 0.9 0.2 0.3 1.2 2.1 0.1 0.0 0.2 0.3 0.2 0.2 0.6 0.6 1.1 0.3 1.6 2.5 1.1 0.6 0.3 0.3 0.7 0.1 1.1 0.9 0.2 0.5 0.7 1.7 0.1 0.0 0.3 4.1 0.1 1.0 7.1 1.2 5.0 1.1 0.6 0.1 0.2 1.5 0.3 0.1 1.5 0.4 0.0 0.1 0.1 0.0 0.0 4.3 0.0 0.0 0.4 0.6 0.8 0.1 0.2 0.6 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.0 1.2 0.2 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.4 0.0 2.9 0.9 0.8 0.3 2.5 0.1 0.1 0.0 0.1 0.2 0.1 0.9 3.2 0.1 0.3 0.5 8.3 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.0 7.4 0.0 0.0 3.1 1.9 0.0 3.3 0.0 9.1 0.4 0.3 2.0 11.7 1.7 0.9 3.3 0.3 2.9 1.0 0.0 0.7 0.7 0.6 0.6 0.9 0.6 0.6 1.1 0.6 0.9 1.0 1.1 1.5 0.2 0.0 0.0 0.0 12.2 0.0 0.1 0.0 0.0 0.8 0.3 0.5 0.5 1.5 0.0 3.7 0.0 6.1 2.7 3.7 0.0 0.4 0.6 0.1 0.0 0.4 0.0 0.0 0.0 0.4 38.3 0.1 0.5 0.2 0.0 0.2 0.0 0.0 17.5 1.7 0.0 0.9 0.0 5.4 0.6 1.2 0.0 6.5 0.0 0.0 3.4 0.6 1.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 9.1 0.2 0.0 8.2 0.0 0.0 0.2 0.1 0.9 0.1 0.1 9.4 0.5 0.1 2.3 0.0 SPRR2G ENSG00000159516 "Small proline rich protein 2G" Q9BYE4 1 153149582-153150890 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "skin 1: 969.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.8;Early spermatids: 5.1;Extravillous trophoblasts: 12.9;Late spermatids: 10.1;Suprabasal keratinocytes: 5.5" "Group enriched" "Detected in many" 15 "head and neck cancer: 256.0;melanoma: 131.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 16 "hTCEpi: 3.3" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.93e-1)" "unprognostic (1.90e-1)" "unprognostic (3.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.69e-2)" 2.2 0.0 0.3 0.0 0.3 0.2 14.3 0.1 0.4 5.4 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.4 0.3 0.9 0.0 0.1 0.1 0.0 0.4 0.3 0.2 0.2 0.0 0.1 2.7 0.3 0.0 0.0 0.0 8.8 0.0 0.5 969.4 0.1 0.0 0.4 0.0 0.1 2.6 0.7 2.1 0.1 0.6 27.9 0.0 34.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.4 0.3 0.9 0.4 0.3 0.3 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 10.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 5.5 0.8 0.0 0.0 0.0 0.0 SUV39H1 "KMT1A, SUV39H" ENSG00000101945 "Suppressor of variegation 3-9 homolog 1" O43463 X 48695554-48709016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Host-virus interaction, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (4.92e-2)" "prognostic favorable (8.93e-5)" "unprognostic (9.51e-2)" "unprognostic (4.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.03e-1)" "unprognostic (3.59e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.91e-7)" "unprognostic (2.29e-3)" "unprognostic (6.47e-3)" "unprognostic (2.01e-1)" "unprognostic (5.67e-2)" 4.0 2.2 4.7 4.2 4.4 13.7 3.5 4.9 5.1 2.9 2.0 3.4 3.1 3.2 12.5 5.0 3.3 1.7 3.6 4.3 5.1 2.6 6.6 2.7 7.5 5.2 5.6 3.8 2.9 2.3 3.0 3.3 4.8 3.0 3.2 3.3 2.6 3.0 4.9 4.4 4.2 2.6 3.9 6.0 3.6 4.9 5.0 9.7 2.6 3.8 7.0 3.4 2.4 4.3 28.7 34.3 13.3 14.0 3.4 4.0 27.0 13.5 10.2 25.8 21.0 21.0 18.7 31.4 8.0 9.9 26.1 19.8 33.0 19.3 15.4 24.2 33.8 12.3 31.8 17.4 2.0 30.7 6.6 3.6 3.7 22.8 11.6 4.2 18.6 20.2 31.9 21.6 14.2 33.1 26.8 32.0 15.7 14.0 32.8 19.3 24.5 33.1 8.6 15.7 17.4 11.4 18.3 17.4 9.8 14.8 26.0 25.5 10.0 15.8 27.0 22.1 23.3 14.6 23.9 26.4 11.8 43.6 17.7 4.9 2.8 6.8 8.5 4.0 6.2 4.6 5.5 9.1 2.2 5.4 6.8 6.6 2.0 10.6 6.5 2.6 11.0 6.5 4.7 4.4 4.9 5.1 4.3 5.1 5.2 5.6 4.8 3.9 5.0 4.3 1.2 6.4 0.0 0.3 3.5 1.8 0.9 2.0 2.8 5.3 2.2 2.5 2.5 2.8 1.3 1.8 0.0 6.5 6.6 2.1 3.9 2.9 0.2 1.3 0.9 1.7 3.0 6.9 0.7 2.9 28.3 1.9 3.1 1.0 1.3 2.9 1.8 6.7 5.2 0.0 1.0 2.6 0.0 2.9 1.6 0.2 1.2 2.4 5.4 1.0 3.0 0.9 6.2 1.0 0.8 2.3 1.7 1.5 7.1 0.6 1.6 2.4 2.6 3.8 0.0 1.8 2.5 3.7 0.8 2.5 1.1 6.2 3.6 1.7 3.2 0.6 SYDE1 "7h3, FLJ13511, SYD1" ENSG00000105137 "Synapse defective Rho GTPase homolog 1" Q6ZW31 19 15107401-15114985 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 140.3;Peritubular cells: 42.2;Sertoli cells: 85.5;Syncytiotrophoblasts: 134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 107.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013328 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA013328: AB_1848705" "unprognostic (9.99e-2)" "unprognostic (3.73e-2)" "unprognostic (8.17e-3)" "unprognostic (1.65e-2)" "unprognostic (6.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.07e-2)" "unprognostic (2.46e-2)" "unprognostic (2.96e-1)" "unprognostic (5.01e-3)" "unprognostic (1.43e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (5.63e-7)" "unprognostic (1.82e-2)" "unprognostic (7.57e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.27e-4)" 23.3 12.6 7.8 5.7 8.0 0.0 17.6 7.4 7.8 27.6 15.7 28.6 3.8 32.9 4.6 6.6 23.2 5.7 20.8 6.9 7.2 16.3 4.9 18.1 3.5 9.7 8.0 23.5 6.0 2.5 6.7 15.4 7.9 18.2 2.5 1.4 6.1 11.5 5.4 8.6 11.7 10.8 7.8 12.9 13.5 4.7 8.5 0.9 12.4 3.8 1.4 23.9 18.8 7.3 11.2 17.4 9.0 23.9 19.9 18.2 7.1 46.9 33.7 44.4 37.5 4.1 7.0 0.0 30.3 46.5 15.2 7.0 7.0 8.1 24.6 0.3 8.0 1.6 34.2 7.6 37.7 0.1 0.1 32.1 5.9 26.6 12.0 26.8 8.2 0.0 0.0 0.1 33.6 5.9 0.0 0.0 14.7 0.3 17.3 0.0 22.4 0.2 11.1 1.8 0.3 17.8 25.9 15.9 31.6 8.7 1.9 1.2 17.5 107.3 32.8 49.6 50.4 0.1 0.3 0.2 29.3 0.1 46.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 8.0 7.4 7.8 6.9 7.2 9.7 8.0 7.9 7.8 8.5 7.3 18.6 3.2 1.1 3.6 0.2 2.4 0.8 1.2 1.8 0.3 0.9 3.2 4.1 1.5 0.8 1.8 0.0 7.6 0.0 0.0 0.0 4.7 10.0 0.7 13.6 15.2 0.0 0.0 0.0 0.4 140.3 16.2 0.0 0.5 0.0 12.8 20.0 0.3 3.4 1.7 0.0 0.0 0.0 1.0 2.7 19.3 29.5 0.6 14.2 6.5 0.0 20.0 0.0 1.0 0.2 1.7 0.0 42.2 0.0 0.5 0.0 6.1 0.1 0.8 85.5 10.7 30.8 3.1 0.6 0.3 2.6 134.5 0.4 7.5 0.0 0.2 TAF5L PAF65B ENSG00000135801 "TATA-box binding protein associated factor 5 like" O75529 1 229593121-229626047 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067941 Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear speckles" "Cytoplasmic bodies" "HPA067941: AB_2685929" "unprognostic (3.41e-1)" "unprognostic (1.34e-1)" "unprognostic (3.39e-2)" "unprognostic (1.93e-1)" "unprognostic (7.46e-2)" "unprognostic (1.94e-1)" "unprognostic (2.91e-1)" "unprognostic (2.36e-1)" "unprognostic (1.63e-1)" "unprognostic (6.84e-2)" "unprognostic (5.17e-3)" "unprognostic (8.16e-3)" "unprognostic (1.91e-3)" "unprognostic (3.21e-1)" "unprognostic (2.99e-1)" "unprognostic (4.99e-2)" "unprognostic (3.11e-1)" 16.3 6.3 7.7 10.5 8.5 22.7 10.5 8.6 8.1 9.2 4.6 12.3 10.6 9.1 5.9 10.6 9.5 11.7 8.4 7.3 7.9 6.6 15.3 11.2 14.0 8.3 8.1 9.3 8.4 9.2 3.8 14.0 8.3 9.2 12.5 10.1 8.2 8.7 14.1 7.2 9.9 11.4 7.5 11.4 9.5 5.5 8.5 14.2 10.5 12.6 10.8 14.0 5.1 9.6 30.2 17.1 23.6 19.8 16.1 16.6 62.4 20.1 23.5 24.3 22.4 23.3 23.9 33.7 20.8 21.4 15.7 24.9 26.4 24.2 22.9 25.5 38.3 26.4 17.7 14.8 17.9 35.3 29.3 18.6 22.9 24.0 20.3 9.4 23.7 34.8 36.1 29.7 22.8 14.6 39.9 18.5 34.1 33.3 13.2 35.0 26.8 34.9 16.6 27.2 23.9 29.4 17.2 22.9 27.9 8.7 27.4 35.6 21.2 20.1 24.7 27.2 42.6 16.1 13.3 37.9 15.4 21.1 32.3 0.0 0.2 0.0 0.4 0.2 0.5 0.2 0.4 0.3 0.3 0.2 0.4 0.4 0.0 0.5 0.3 0.1 0.4 0.2 7.7 8.5 8.6 8.1 7.3 7.9 8.3 8.1 8.3 7.5 8.5 9.6 15.9 3.2 9.4 19.2 8.2 5.7 4.8 2.9 6.2 5.5 8.4 5.3 7.3 5.7 7.1 3.7 12.5 11.0 14.6 12.3 1.9 4.2 3.4 11.0 8.9 8.0 12.0 7.6 11.7 8.3 32.8 7.0 6.1 12.7 0.0 6.1 6.8 13.6 9.6 6.7 15.7 10.2 6.1 6.3 8.4 4.7 4.7 10.9 5.4 13.1 11.8 3.8 4.1 22.1 24.0 6.9 8.3 4.1 10.2 6.6 6.9 3.0 5.1 9.0 13.1 15.4 11.5 6.0 4.6 9.6 5.3 10.4 8.8 5.6 9.9 7.2 TARBP2 Trbp ENSG00000139546 "TARBP2 subunit of RISC loading complex" Q15633 12 53500921-53506431 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051181, HPA061454, CAB069406" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear bodies" "CAB069406: AB_1622301, HPA051181: AB_2681376, HPA061454: AB_2684526" "unprognostic (1.71e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (6.61e-3)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.04e-1)" "unprognostic (4.72e-3)" "unprognostic (1.44e-1)" "unprognostic (1.31e-2)" "unprognostic (5.58e-2)" "prognostic unfavorable (4.75e-6)" "unprognostic (8.06e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (4.31e-1)" 9.2 13.1 9.8 9.2 10.0 6.8 8.9 13.4 11.3 8.9 9.5 9.5 9.0 8.5 7.9 13.1 11.7 6.7 9.7 9.6 10.1 18.6 20.6 10.1 10.5 10.0 10.0 8.0 18.7 8.5 8.5 13.8 9.9 11.3 5.5 6.7 11.0 5.1 9.8 9.8 9.5 6.1 9.9 15.2 12.4 13.1 10.8 10.3 12.0 7.1 9.0 10.4 8.9 10.5 25.5 69.1 26.8 29.6 15.3 20.8 35.0 22.6 19.2 34.1 20.3 61.2 33.5 24.5 44.6 24.9 22.2 20.0 32.8 34.1 19.9 30.5 54.1 28.6 26.6 43.9 33.3 48.0 31.9 24.3 21.0 35.2 16.5 23.2 41.2 36.6 37.1 38.3 24.9 102.9 32.5 62.9 53.0 19.7 37.1 23.9 14.4 31.6 22.6 26.4 34.8 24.8 11.8 28.7 58.9 19.1 40.4 63.7 22.1 31.2 29.8 11.9 27.4 19.7 39.6 26.1 34.8 24.2 35.6 2.1 11.5 5.7 13.9 11.9 13.3 10.9 13.3 12.8 14.9 15.3 13.7 13.6 0.7 13.1 7.7 13.3 11.7 12.5 9.8 10.0 13.4 11.3 9.6 10.1 10.0 10.0 9.9 9.9 10.8 10.5 5.2 0.0 8.2 4.6 10.7 6.4 10.5 15.3 17.1 9.3 12.0 10.0 6.0 15.7 11.2 9.2 10.4 46.5 7.2 9.8 21.5 20.7 10.7 7.9 8.8 11.6 5.4 9.4 2.3 26.2 48.9 9.3 13.7 7.2 10.8 10.5 12.1 18.4 25.6 1.7 3.1 10.8 18.3 9.3 4.7 23.8 5.6 7.9 14.2 1.0 12.2 10.2 10.3 4.5 6.2 16.8 9.9 4.1 15.6 11.2 11.3 28.6 7.1 14.2 0.0 4.0 10.0 11.6 13.0 14.4 4.7 32.2 9.0 9.9 14.8 10.1 TET1 "bA119F7.1, CXXC6, KIAA1676, LCX" ENSG00000138336 "Tet methylcytosine dioxygenase 1" Q8NFU7 10 68560337-68694487 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9" "Cell type enhanced" "Detected in many" "Astrocytes: 54.5;Extravillous trophoblasts: 79.9;Oligodendrocyte precursor cells: 44.7;Oligodendrocytes: 45.3;Theca cells: 43.7" "Cancer enriched" "Detected in some" 15 "testis cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;HAP1: 20.4;K-562: 12.0;NTERA-2: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019032, HPA057273" Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane" "HPA019032: AB_1847363, HPA057273: AB_2683391" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "unprognostic (9.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (8.15e-2)" "unprognostic (3.60e-3)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (7.90e-3)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-3)" "unprognostic (2.88e-4)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (9.52e-3)" 0.4 0.2 0.6 0.2 1.2 0.3 0.4 4.9 0.7 0.7 0.8 0.4 0.1 0.9 0.6 0.2 0.5 0.3 0.3 0.3 0.9 0.3 0.2 0.2 0.3 0.9 1.3 0.8 0.2 0.7 0.3 1.2 1.1 0.6 0.3 1.5 1.0 0.3 0.9 0.3 0.2 0.5 1.0 0.3 0.4 0.2 1.1 2.0 0.5 0.3 0.3 0.2 0.4 2.2 0.7 0.8 8.0 9.0 0.8 0.7 17.7 0.4 1.0 0.7 1.2 5.5 0.3 0.0 0.3 0.8 0.1 0.0 20.4 0.0 0.8 0.3 3.3 2.1 0.0 4.9 1.2 1.9 1.0 1.0 0.1 0.5 0.1 1.6 0.1 3.5 12.0 1.4 0.7 0.6 3.3 1.4 11.9 0.0 1.1 3.2 2.5 0.2 0.4 0.8 2.2 3.5 0.4 0.5 1.6 7.9 1.0 1.5 0.3 0.7 1.6 0.0 0.6 0.5 0.6 3.2 0.2 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.2 0.5 0.0 0.6 1.2 4.9 0.7 0.3 0.9 0.9 1.3 1.1 1.0 1.1 2.2 6.3 3.2 6.2 54.5 2.5 1.1 1.8 0.4 5.2 2.5 7.0 9.5 7.2 1.5 2.6 0.0 10.4 21.0 3.0 0.2 0.0 2.7 0.8 3.6 34.2 4.8 13.8 2.5 15.6 0.4 79.9 15.4 1.5 2.9 0.0 13.6 5.7 2.5 3.9 35.3 20.6 0.3 4.1 0.0 0.3 1.7 25.7 0.8 1.8 12.2 0.4 16.1 5.2 44.7 45.3 0.6 0.0 20.7 7.3 1.4 0.0 0.9 0.8 12.5 6.6 21.9 10.7 0.5 1.5 0.8 1.1 27.9 2.6 43.7 0.6 0.4 TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.3;placenta: 191.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2284.2;Hepatic stellate cells: 872.4;Syncytiotrophoblasts: 879.2" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.3;neutrophil: 1.3;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "HHSteC: 386.2;HUVEC TERT2: 742.5;LHCN-M2: 459.9;TIME: 451.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" NA NA 58100000 87000000 "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" 67.5 12.6 2.6 20.5 3.4 8.2 52.3 4.9 5.8 41.5 7.4 23.3 52.5 25.7 18.5 33.3 35.6 57.6 38.5 4.1 2.2 56.3 272.3 126.7 33.3 6.8 2.5 26.5 25.0 7.1 6.1 191.2 3.9 15.7 27.4 4.5 15.0 12.8 26.8 19.8 41.8 30.7 3.7 20.7 19.2 6.9 3.6 11.1 36.2 42.8 17.7 52.9 29.8 3.2 38.9 24.7 29.3 0.8 224.3 267.7 0.7 66.0 156.3 42.7 65.1 22.6 192.6 0.7 27.3 52.7 74.7 2.1 15.9 3.6 110.3 1.9 7.6 12.3 73.8 197.3 386.2 0.9 0.4 123.1 5.1 232.8 61.9 93.4 742.5 0.7 31.2 0.7 459.9 35.4 4.6 0.7 22.9 0.8 68.8 0.3 40.2 0.3 72.9 1.4 0.3 0.5 56.7 2.1 3.5 95.8 0.7 0.2 451.4 30.6 29.0 61.4 13.5 1.1 1.7 0.4 239.4 0.6 35.4 3.3 0.2 0.2 0.2 0.1 0.1 0.4 0.1 0.0 0.2 0.5 0.2 0.2 1.3 0.5 0.1 2.7 0.1 2.3 2.6 3.4 4.9 5.8 4.1 2.2 6.8 2.5 3.9 3.7 3.6 3.2 99.2 35.3 335.5 1.3 4.4 20.8 2.9 33.5 4.6 0.6 16.1 9.1 7.0 173.0 102.5 38.6 0.0 59.5 4.8 0.5 13.7 140.0 41.5 7.3 74.2 287.1 105.0 43.1 0.7 273.1 2284.2 283.0 12.2 5.3 13.9 1.5 872.4 382.1 50.2 1.7 0.2 11.3 158.7 63.7 41.3 15.2 171.8 21.9 26.6 13.1 33.7 33.1 1.0 0.0 0.1 157.6 34.1 70.0 9.5 8.0 36.6 109.4 45.2 1.1 216.9 141.2 127.8 2.7 0.5 10.2 18.5 879.2 8.1 30.6 18.5 16.7 TH DYT5b ENSG00000180176 "Tyrosine hydroxylase" P07101 11 2163929-2171815 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis, Neurotransmitter biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Dystonia, FDA approved drug targets, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "adrenal gland: 196.6;brain: 270.9" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 9.0;Extravillous trophoblasts: 12.4;Leydig cells: 3.4;Syncytiotrophoblasts: 2.2" "Cancer enriched" "Detected in some" 5 "urothelial cancer: 4.0" "Group enriched" "Detected in many" 5 "midbrain: 192.4;pons: 270.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "PC-3: 60.8;SK-BR-3: 21.0" "Region enhanced" "Detected in many" "olfactory bulb: 178.8" "Region enriched" "Detected in many" 20 "midbrain: 594.4" "CAB002522, HPA013768, HPA014010, HPA061003, CAB072340" Enhanced Supported Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB002522: AB_564047, CAB072340: , HPA013768: , HPA014010: , HPA061003: AB_2630374" "unprognostic (1.31e-1)" "unprognostic (1.30e-1)" "unprognostic (9.08e-2)" "unprognostic (1.75e-4)" "unprognostic (8.82e-3)" "unprognostic (5.88e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-3)" "unprognostic (3.83e-2)" "unprognostic (4.39e-4)" "unprognostic (4.97e-1)" "unprognostic (3.61e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-1)" "unprognostic (2.43e-1)" "unprognostic (2.70e-2)" "unprognostic (2.18e-2)" 3.3 196.6 1.9 0.1 3.0 0.0 0.0 0.2 1.3 0.6 0.2 0.1 0.0 0.5 0.1 0.7 0.2 0.4 0.1 1.3 46.5 0.4 0.4 0.0 0.0 13.9 192.4 0.7 0.2 0.0 1.7 0.1 270.9 0.3 0.0 0.1 0.1 0.0 0.0 0.8 0.5 0.0 0.8 0.2 0.3 0.5 14.6 0.0 0.0 0.0 0.0 1.4 1.5 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 60.8 0.0 0.0 0.0 0.1 0.1 1.1 0.2 0.0 21.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.0 0.2 1.3 1.3 46.5 13.9 192.4 270.9 0.8 14.6 1.6 0.3 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.2 1.8 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.4 9.0 0.4 0.0 0.0 0.1 0.0 12.4 0.4 0.0 0.3 0.0 0.0 1.1 0.2 0.5 0.0 0.3 0.1 0.0 0.0 0.3 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 2.2 0.1 0.3 0.2 0.2 THOC6 "fSAP35, MGC2655, WDR58" ENSG00000131652 "THO complex 6" Q86W42 16 3024027-3027755 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transport" "Developmental protein, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.8;Extravillous trophoblasts: 121.1;Prostatic glandular cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052953 Uncertain Supported "Nucleoplasm,Nuclear speckles" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA052953: AB_2681997" "unprognostic (2.07e-2)" "unprognostic (4.13e-3)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (7.82e-3)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (3.59e-1)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (9.43e-2)" 17.0 16.9 8.6 16.1 9.1 23.5 15.3 9.6 11.2 16.1 9.7 17.9 18.8 20.3 6.0 19.3 13.9 10.5 15.8 8.6 9.2 22.2 21.3 17.5 20.8 11.6 9.1 11.6 12.9 10.8 17.4 18.2 11.8 21.1 10.1 2.1 15.2 12.2 25.9 24.9 19.2 12.5 9.2 22.7 15.6 10.4 10.2 19.6 15.7 8.4 16.1 17.1 16.5 9.5 37.3 59.6 42.0 45.0 21.1 23.9 74.4 11.3 25.7 25.7 37.8 39.6 42.8 70.0 36.0 18.9 19.1 49.9 46.3 35.6 14.0 62.3 59.9 38.0 58.6 58.7 35.9 56.2 80.0 24.3 42.6 31.4 76.9 32.4 24.1 39.7 56.1 36.5 12.8 87.0 32.0 103.3 76.2 21.4 25.3 84.7 31.6 82.4 27.1 18.6 86.4 41.0 31.8 49.9 21.7 18.1 35.9 60.0 20.1 26.8 61.1 30.6 41.3 26.3 24.3 85.5 7.0 38.1 27.3 2.4 61.3 13.6 35.2 62.2 36.2 37.8 32.6 34.7 88.6 43.2 37.1 39.1 4.4 38.8 35.7 74.3 38.0 45.4 8.6 9.1 9.6 11.2 8.6 9.2 11.6 9.1 11.8 9.2 10.2 9.5 11.0 19.2 7.4 1.6 24.7 68.2 84.9 59.0 30.7 3.7 22.1 20.8 3.3 14.3 18.9 18.4 2.1 107.8 23.3 23.2 35.2 33.1 5.4 17.9 19.0 17.9 25.8 30.3 1.9 23.5 121.1 24.6 15.3 25.8 12.0 15.6 6.4 10.3 51.8 3.3 1.7 32.3 44.7 19.4 37.3 3.2 14.9 23.4 24.9 2.8 39.6 3.2 15.5 0.5 4.2 21.5 28.0 12.0 19.7 109.4 32.1 32.0 8.7 2.4 6.6 23.4 31.9 5.3 23.3 23.3 44.9 77.2 20.4 20.9 42.2 46.8 TLE6 "FLJ14009, GRG6" ENSG00000104953 "TLE family member 6, subcortical maternal complex member" Q9H808 19 2977538-2995179 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 7.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 8.6;Collecting duct cells: 12.9;Distal tubular cells: 7.9;Extravillous trophoblasts: 10.1;Syncytiotrophoblasts: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 18.6;SK-BR-3: 14.0;U-266/70: 14.5;U-698: 16.5;U-937: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.32e-1)" "unprognostic (1.28e-2)" "unprognostic (1.63e-5)" "unprognostic (4.05e-3)" "unprognostic (4.36e-2)" "unprognostic (4.58e-2)" "unprognostic (3.85e-2)" "unprognostic (1.24e-1)" "unprognostic (4.85e-3)" "unprognostic (8.00e-2)" "unprognostic (2.62e-3)" "unprognostic (1.52e-1)" "unprognostic (3.31e-4)" "unprognostic (3.34e-1)" "unprognostic (2.81e-1)" "unprognostic (1.92e-2)" "unprognostic (7.60e-3)" 0.8 1.1 0.7 0.2 0.6 0.0 1.8 1.7 0.8 1.1 0.3 1.2 0.6 1.6 2.7 0.6 0.9 0.2 1.1 0.4 2.0 3.3 3.8 2.3 0.8 0.9 1.0 0.4 1.8 2.6 1.7 4.9 0.8 1.3 1.3 1.9 3.3 3.2 0.3 0.7 0.4 0.8 0.7 1.2 1.0 3.3 2.9 1.1 7.3 0.1 0.5 1.0 0.6 0.9 4.7 6.1 0.1 2.6 0.1 0.0 18.6 0.0 0.1 0.4 1.0 0.0 1.4 8.6 1.4 0.5 1.5 0.1 2.3 1.3 0.3 7.2 1.1 0.0 0.2 0.7 0.7 0.2 1.5 1.1 0.9 0.0 0.2 1.4 1.1 6.3 1.5 0.1 0.5 3.1 0.0 0.4 0.0 9.1 1.2 5.0 0.4 7.2 1.7 1.1 0.4 1.7 0.4 14.0 5.6 0.5 3.7 0.8 1.0 0.6 0.8 0.4 0.4 14.5 10.6 16.5 3.4 12.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.2 0.5 0.0 0.1 0.0 1.0 0.1 0.0 0.3 0.1 0.7 0.6 1.7 0.8 0.4 2.0 0.9 1.0 0.8 0.7 2.9 0.9 0.5 0.0 8.6 0.0 0.8 0.1 1.9 1.3 1.8 3.1 4.0 3.7 1.6 4.3 1.6 12.9 0.0 6.1 0.2 2.4 7.9 1.7 0.8 1.0 0.6 0.7 3.6 0.0 0.5 1.0 10.1 0.7 1.5 2.6 0.0 0.2 0.4 3.1 1.4 0.0 0.9 2.4 2.0 0.3 0.4 2.9 0.3 0.3 5.4 0.0 0.0 6.9 0.0 0.0 0.5 1.0 0.6 0.4 0.2 0.6 0.1 0.7 0.1 0.9 0.0 0.0 0.5 0.2 4.8 0.7 0.0 8.6 0.2 0.5 1.5 0.9 TLX3 "HOX11L2, RNX" ENSG00000164438 "T cell leukemia homeobox 3" O43711 5 171309248-171312139 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "brain: 9.0" "Cell type enriched" "Detected in some" 6 "Extravillous trophoblasts: 7.7" "Cancer enhanced" "Detected in some" "cervical cancer: 1.7" "Group enriched" "Detected in many" 6 "cerebellum: 9.0;medulla oblongata: 2.3;spinal cord: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 25.9" "Region enriched" "Detected in single" 7 "cerebellum: 2.2" "Region enriched" "Detected in some" 8 "cerebellum: 15.5" "HPA030504, HPA060957, HPA069359" Enhanced Enhanced Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA030504: AB_2732458, HPA060957: AB_2732655, HPA069359: AB_2732130" "unprognostic (3.52e-2)" "unprognostic (2.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (2.76e-2)" "unprognostic (4.48e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 2.3 0.6 1.0 5.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 TMPRSS13 "MSPL, MSPS, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900641-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7;skin 1: 41.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.9;Extravillous trophoblasts: 21.2;Glandular and luminal cells: 10.9;Ionocytes: 16.2;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.8;BEWO: 29.9;MCF7: 27.0;SK-BR-3: 42.8;T-47d: 43.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.08e-3)" "unprognostic (5.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (5.61e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-6)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.44e-1)" 0.3 0.4 0.2 0.7 0.2 0.6 7.1 0.0 0.7 6.7 0.0 0.4 0.3 0.6 0.6 15.7 0.3 0.4 0.1 0.9 0.0 2.6 0.2 3.9 1.2 0.0 0.0 0.1 2.5 0.0 0.3 2.9 0.0 1.4 0.4 0.0 11.0 0.1 0.2 41.0 0.8 0.2 0.0 1.5 0.2 0.4 0.0 0.9 6.6 0.0 4.8 0.5 9.3 0.1 13.8 0.1 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 10.2 0.1 0.7 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.5 0.7 0.0 27.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 1.4 0.0 4.0 0.4 0.1 0.0 42.8 0.6 1.7 43.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.2 0.2 0.2 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.6 0.0 0.2 1.7 4.6 1.7 1.2 0.0 7.4 4.6 1.4 7.2 5.3 0.0 0.0 15.9 0.2 0.3 0.0 8.3 0.3 2.4 1.3 0.2 0.0 0.0 0.2 1.2 21.2 0.3 0.5 10.9 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.5 16.2 1.2 1.9 0.8 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 5.7 3.9 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 5.2 8.0 19.4 0.4 0.5 0.8 9.0 TMX1 "PDIA11, TMX, TXNDC, TXNDC1" ENSG00000139921 "Thioredoxin related transmembrane protein 1" Q9H3N1 14 51240162-51257655 "Predicted membrane proteins, Transporters" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003085 Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 26000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" Nucleoli "HPA003085: AB_1080424" "unprognostic (1.83e-1)" "unprognostic (7.42e-2)" "unprognostic (6.97e-3)" "unprognostic (1.49e-2)" "unprognostic (2.63e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.29e-6)" "unprognostic (3.70e-2)" "unprognostic (1.51e-1)" "unprognostic (6.84e-2)" "unprognostic (2.44e-3)" "unprognostic (5.07e-2)" "unprognostic (9.30e-2)" "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (1.18e-1)" "unprognostic (3.21e-3)" 11.0 8.8 5.8 10.8 6.3 10.7 11.3 6.7 8.7 7.8 7.4 12.3 10.6 8.1 10.8 9.1 6.6 8.5 4.8 5.4 6.6 10.2 12.6 9.3 12.4 6.5 6.8 6.6 9.1 9.4 5.5 13.2 7.0 7.9 12.2 6.8 8.3 9.2 5.2 9.8 9.3 9.9 6.9 10.7 10.4 5.0 7.0 11.6 11.4 4.4 10.5 13.0 6.6 7.0 27.0 23.8 33.8 18.4 26.0 20.3 35.5 33.5 26.8 33.2 42.2 24.9 49.0 38.8 30.0 22.6 15.6 26.1 60.3 21.5 60.4 38.6 19.6 28.4 19.4 24.7 22.4 66.2 27.4 24.4 19.5 22.2 16.3 24.0 29.7 31.2 23.6 25.9 32.1 32.6 29.7 35.5 38.3 42.2 28.5 30.9 60.9 23.4 32.2 34.8 21.1 15.5 26.6 17.8 24.6 22.2 25.8 28.6 19.0 34.9 32.2 24.8 30.9 22.4 23.9 31.4 15.4 36.6 33.5 10.5 12.2 6.2 8.6 14.7 10.6 7.7 8.8 9.0 13.6 6.3 8.5 10.1 4.3 11.5 11.0 15.7 11.0 12.4 5.8 6.3 6.7 8.7 5.4 6.6 6.5 6.8 7.0 6.9 7.0 7.0 43.0 38.5 29.1 24.5 55.9 108.6 63.1 80.5 71.2 13.7 40.7 20.8 9.2 44.3 55.7 35.0 12.5 73.9 82.6 38.2 9.8 62.1 2.5 22.0 42.2 47.5 17.4 81.2 8.9 67.6 149.3 48.4 32.1 28.0 43.6 24.4 43.2 44.0 73.2 10.1 11.2 29.2 63.1 61.1 84.3 4.3 24.8 65.7 55.2 18.7 70.0 27.0 46.4 22.1 25.2 50.3 44.0 28.6 79.2 58.4 29.3 32.4 42.2 32.6 59.2 37.3 49.4 59.5 68.7 79.0 97.3 57.7 62.5 58.7 46.5 59.5 TRIM64B ENSG00000189253 "Tripartite motif containing 64B" A6NI03 11 89869282-89876017 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 17 "placenta: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 332 "basophil: 33.2" "Lineage enriched" "Detected in single" 332 "granulocytes: 33.2" "Not detected" "Not detected" HPA045370 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA045370: AB_2679298" "unprognostic (2.08e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 33.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TSPAN9 NET-5 ENSG00000011105 "Tetraspanin 9" O75954 12 3077355-3286564 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 128.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 68.7;Extravillous trophoblasts: 105.1;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 96.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 213.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 58.1" HPA014002 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" Cytosol "HPA014002: AB_2304038" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-2)" "unprognostic (3.53e-2)" "unprognostic (3.11e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" "unprognostic (1.26e-2)" "unprognostic (1.89e-1)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" 25.4 12.9 11.0 7.1 12.1 0.6 25.0 96.6 13.5 29.6 9.7 18.0 7.9 32.3 11.5 15.4 23.2 35.2 128.8 6.9 12.6 45.8 54.8 35.8 5.4 12.3 13.0 35.3 13.1 28.1 8.6 58.7 14.5 27.6 6.2 14.8 18.0 24.4 16.8 27.9 12.3 23.6 8.6 20.6 13.4 5.1 17.1 19.1 18.4 12.4 7.1 18.4 22.3 7.6 1.5 12.7 20.1 16.1 19.2 15.5 48.3 26.7 82.3 20.1 26.1 30.6 11.6 0.8 23.9 14.6 19.7 3.1 9.5 9.6 11.8 5.0 9.3 36.3 8.5 20.6 42.2 0.2 3.0 17.7 7.4 40.4 16.9 50.4 55.7 1.1 1.0 1.1 17.6 16.7 0.0 0.8 25.5 7.8 7.4 9.9 213.0 3.1 61.7 7.4 36.8 22.6 18.8 36.6 16.4 45.9 13.7 0.2 27.2 8.5 28.8 14.8 25.7 0.2 0.6 0.3 20.3 0.5 10.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.2 11.0 12.1 96.6 13.5 6.9 12.6 12.3 13.0 14.5 8.6 17.1 7.6 60.1 0.0 4.1 10.4 0.8 19.2 13.3 22.4 13.1 68.7 19.8 9.0 50.1 11.5 6.5 12.9 2.1 53.1 0.2 1.7 5.9 21.1 3.0 2.3 24.9 43.1 6.0 5.3 16.8 9.1 105.1 22.2 2.0 5.7 0.0 13.0 41.0 36.7 6.2 33.7 45.5 2.3 2.0 3.2 3.5 4.1 17.4 7.1 12.4 30.9 0.8 4.0 0.0 9.0 2.0 9.9 0.6 17.3 1.4 13.8 2.4 22.4 2.5 4.7 19.7 1.4 20.9 1.3 3.4 9.7 11.9 80.7 1.5 6.4 2.5 10.5 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 282.2;monocytes: 215.5;NK-cells: 193.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA037444 Approved Approved Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA037444: AB_10672491" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (3.80e-2)" "unprognostic (6.92e-3)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (3.43e-3)" "unprognostic (6.64e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.59e-7)" "unprognostic (2.04e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" 26.7 29.7 33.0 25.5 33.7 41.8 22.8 35.9 40.6 27.7 32.5 29.6 24.7 23.1 53.0 43.1 18.8 28.7 56.7 33.4 38.0 28.2 44.2 22.6 32.1 37.5 37.7 12.6 70.5 41.8 21.0 39.9 38.7 25.4 33.7 16.0 25.2 30.3 60.7 18.8 26.9 35.6 35.5 23.7 26.5 26.0 36.1 34.5 35.4 69.1 33.1 40.7 23.5 38.3 42.9 23.9 53.6 55.1 69.2 83.0 74.8 38.9 55.5 43.3 44.4 26.0 26.4 22.0 13.7 88.7 93.7 35.1 62.3 84.9 67.9 33.7 22.7 31.6 28.5 86.6 86.2 13.1 70.1 48.1 137.7 57.9 87.1 40.1 78.1 100.8 94.2 13.7 80.1 64.0 35.1 55.9 59.8 60.9 33.8 41.8 35.0 39.1 66.3 17.8 36.0 53.0 45.2 36.2 77.0 89.4 31.0 52.8 49.7 47.6 41.7 54.9 43.1 17.1 14.3 43.6 57.1 38.4 35.8 112.4 50.0 63.8 66.3 68.2 26.2 26.2 44.8 40.4 45.0 25.4 40.7 41.4 37.3 102.3 78.5 56.4 51.6 63.6 33.0 33.7 35.9 40.6 33.4 38.0 37.5 37.7 38.7 35.5 36.1 38.3 17.6 6.4 18.4 0.0 26.4 32.5 24.1 33.0 11.4 24.2 37.7 24.9 48.1 30.0 21.6 27.6 8.4 84.9 87.3 38.6 56.7 49.7 23.6 15.0 23.9 27.1 41.8 102.5 0.0 79.4 282.2 24.9 15.8 13.8 21.5 13.1 22.1 41.7 152.7 26.9 0.0 58.1 32.6 72.2 105.7 61.3 25.7 67.6 35.6 0.0 215.5 28.3 193.6 0.0 0.0 71.8 31.9 30.9 25.7 46.0 49.7 62.2 23.4 21.7 39.5 14.8 31.4 123.5 79.4 19.0 40.3 65.7 36.2 16.0 35.5 34.6 USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18150170-18177397 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 46.9;Extravillous trophoblasts: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 181.8;BJ hTERT+ SV40 Large T+ RasG12V: 196.2" HPA044768 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol Vesicles "HPA044768: AB_10963697" "unprognostic (2.06e-1)" "unprognostic (3.55e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (5.42e-2)" "unprognostic (3.29e-2)" "unprognostic (5.11e-3)" "unprognostic (1.81e-1)" "unprognostic (1.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (4.29e-3)" "unprognostic (2.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-2)" "unprognostic (8.38e-2)" 10.8 5.0 3.6 5.1 3.8 8.1 8.3 3.3 4.5 4.0 4.0 5.0 6.0 3.2 7.8 4.0 7.3 6.6 4.4 3.7 3.9 5.9 23.6 7.9 9.2 5.1 3.9 2.9 4.2 3.6 5.7 5.7 4.2 5.3 4.4 0.7 14.0 2.5 3.8 3.4 6.7 4.0 7.0 11.0 7.2 9.7 4.1 15.0 7.3 5.5 6.5 4.0 3.6 3.7 14.4 14.6 4.2 18.2 18.2 13.5 18.4 7.3 17.5 181.8 196.2 2.2 20.1 0.2 10.8 4.0 57.5 4.9 21.6 6.4 6.2 64.4 29.4 28.3 1.9 27.0 2.1 6.9 25.7 6.0 2.5 12.8 0.0 1.0 40.8 20.6 1.4 1.7 1.8 24.9 33.4 16.7 12.7 15.6 11.0 13.1 28.4 0.0 3.6 12.4 15.2 11.9 8.8 15.0 71.9 16.3 9.9 6.6 66.7 1.3 3.5 4.1 7.5 3.4 45.4 0.2 16.3 17.1 10.5 3.2 3.9 8.3 8.5 11.0 10.7 5.3 7.2 11.1 1.8 3.4 8.2 9.6 0.7 13.3 8.6 3.3 13.1 5.3 3.6 3.8 3.3 4.5 3.7 3.9 5.1 3.9 4.2 7.0 4.1 3.7 9.7 9.6 4.8 0.7 2.5 1.7 4.5 5.7 2.2 0.2 8.4 8.3 1.4 8.6 6.9 0.0 0.0 4.6 3.0 6.2 46.9 5.9 1.6 20.1 2.5 8.4 3.0 1.3 0.5 11.1 31.9 7.1 4.1 6.3 0.0 8.5 11.0 5.5 8.7 0.0 0.6 3.5 6.1 6.3 0.8 1.7 3.7 3.8 3.6 0.0 1.6 5.1 8.2 2.0 0.3 13.4 3.2 7.2 2.3 2.5 5.4 8.0 12.2 0.3 6.6 8.0 2.5 10.9 1.0 4.0 1.0 1.5 5.0 5.5 2.8 2.9 VAPB "ALS8, VAP-B, VAP-C" ENSG00000124164 "VAMP associated protein B and C" O95292 20 58389229-58451101 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013144, CAB013722" Supported Enhanced "Endoplasmic reticulum" NA NA 240000 "Cluster 32: T-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "CAB013722: , HPA013144: AB_1858717" "unprognostic (3.28e-3)" "unprognostic (3.88e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (9.36e-2)" "unprognostic (3.15e-2)" "unprognostic (4.76e-3)" "unprognostic (2.80e-1)" "unprognostic (4.47e-2)" "unprognostic (8.06e-3)" "unprognostic (3.11e-2)" "unprognostic (2.99e-1)" "prognostic favorable (1.08e-8)" "unprognostic (1.05e-1)" "unprognostic (5.31e-1)" "unprognostic (6.34e-3)" "unprognostic (2.99e-2)" 15.7 36.4 32.1 11.2 30.4 4.2 14.2 29.6 30.1 13.7 20.3 24.2 19.6 16.4 10.3 19.3 14.9 9.7 29.4 28.8 33.5 24.8 35.0 14.1 9.6 34.6 34.0 17.9 18.9 27.9 21.0 9.2 36.2 17.8 9.9 14.3 16.2 12.3 46.4 13.0 18.2 11.6 36.4 15.0 19.0 8.8 37.0 12.2 23.3 39.6 6.7 18.1 12.9 31.5 31.0 30.4 33.6 18.0 30.3 12.5 29.5 27.0 11.2 41.0 20.1 123.0 29.0 27.2 37.7 18.3 32.3 57.6 27.1 38.9 24.6 12.8 20.2 16.5 32.2 38.9 30.2 15.5 19.8 28.9 44.4 22.8 18.7 19.8 20.5 26.7 39.5 14.9 20.0 96.7 24.5 30.6 17.7 60.2 40.0 24.2 31.3 18.0 31.6 40.7 47.1 32.6 44.7 117.0 48.0 18.4 48.0 23.2 28.6 65.8 31.9 33.3 36.9 19.9 23.1 31.4 55.7 16.8 33.8 2.1 2.3 3.1 3.9 2.4 4.5 2.8 4.6 3.2 2.3 2.3 3.3 4.8 3.7 3.7 3.0 2.3 2.7 2.6 32.1 30.4 29.6 30.1 28.8 33.5 34.6 34.0 36.2 36.4 37.0 31.5 22.5 44.8 26.8 31.6 18.7 11.7 13.5 17.2 23.9 29.7 23.6 21.1 46.5 24.3 16.6 31.3 29.2 34.8 20.7 28.6 35.2 35.1 5.0 18.2 20.9 23.2 21.7 18.7 34.3 30.5 50.3 24.0 20.4 16.0 9.5 23.3 15.7 40.3 16.1 35.3 34.7 23.4 22.4 18.5 10.0 6.1 18.6 17.3 14.2 40.3 22.8 34.3 20.6 35.2 43.7 37.5 22.4 25.2 14.0 17.7 38.9 42.9 19.1 29.7 13.1 22.2 26.0 22.0 29.4 18.2 10.5 44.5 20.5 37.4 27.6 16.6 VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526983 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 443.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 52.7" "Group enriched" "Detected in all" 7 "granulocytes: 52.7;monocytes: 22.7" "Cell line enhanced" "Detected in all" "HMC-1: 270.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 32000000 "Cluster 52: Eosinophils - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: AB_2213431, HPA005724: AB_1858721" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (4.70e-2)" "unprognostic (7.85e-3)" "unprognostic (8.31e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-2)" "unprognostic (3.64e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (5.91e-7)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.08e-2)" 54.5 24.6 9.3 75.2 8.3 94.0 42.5 9.2 12.6 37.7 11.0 88.9 61.9 89.1 6.0 37.5 54.4 27.0 36.4 8.1 9.4 39.1 27.3 58.2 48.7 13.0 10.9 22.5 20.6 10.7 17.1 31.5 13.8 43.8 20.4 1.9 30.7 39.1 12.5 32.8 63.6 36.5 11.7 107.0 70.5 14.7 15.0 24.9 27.6 8.5 32.0 71.6 39.0 12.0 68.9 66.3 20.6 35.6 10.2 17.4 50.5 70.2 52.8 47.4 40.9 30.1 142.0 31.2 55.7 56.4 31.3 60.6 6.2 69.5 15.9 87.0 14.8 183.7 32.3 55.4 56.6 68.1 270.1 26.8 38.2 44.5 28.5 38.3 71.1 25.8 112.1 67.5 29.4 53.7 30.3 58.7 36.0 65.1 44.5 21.6 12.6 12.2 40.9 216.2 23.0 16.3 83.6 41.7 48.2 13.0 45.7 115.2 107.0 74.7 74.4 24.7 112.4 32.8 43.3 54.7 52.4 82.3 92.3 13.3 8.5 52.7 4.1 13.9 2.8 3.4 3.3 3.9 5.5 3.3 2.1 2.5 34.5 4.0 22.7 2.1 2.6 5.8 9.3 8.3 9.2 12.6 8.1 9.4 13.0 10.9 13.8 11.7 15.0 12.0 80.9 16.0 19.5 2.9 99.4 98.3 95.6 48.8 37.0 6.9 53.5 57.0 19.0 48.6 41.5 33.1 27.1 67.1 85.9 202.3 17.6 138.6 3.2 33.9 30.5 77.0 114.7 20.0 2.6 98.2 443.6 26.7 81.6 58.1 83.1 17.4 48.5 15.8 160.1 6.7 3.4 159.3 44.7 132.5 232.0 3.8 26.1 192.9 49.8 10.3 162.9 13.2 185.3 2.0 2.3 212.5 245.5 49.2 38.2 73.4 134.6 20.4 18.6 14.7 131.5 46.5 89.4 18.9 15.5 38.7 77.7 140.9 95.7 21.0 129.5 144.8 VGLL3 VGL-3 ENSG00000206538 "Vestigial like family member 3" A8MV65 3 86876388-86991149 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.1" "Cell type enhanced" "Detected in many" "Early spermatids: 138.1;Extravillous trophoblasts: 178.1;Late spermatids: 71.8;Leydig cells: 132.3;Peritubular cells: 149.3;Skeletal myocytes: 65.9;Syncytiotrophoblasts: 80.7" "Cancer enhanced" "Detected in many" "prostate cancer: 7.9;urothelial cancer: 6.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 518.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054983 Approved Approved Nucleoli,Cytosol NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli, Cytosol" "HPA054983: AB_2682663" "unprognostic (9.08e-2)" "unprognostic (4.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.54e-1)" "unprognostic (2.98e-2)" "unprognostic (1.13e-1)" "unprognostic (2.77e-2)" "unprognostic (3.86e-2)" "unprognostic (1.38e-2)" "unprognostic (4.94e-2)" "unprognostic (3.70e-2)" "unprognostic (3.44e-2)" "unprognostic (2.73e-8)" "unprognostic (3.85e-3)" "unprognostic (1.27e-1)" "unprognostic (5.42e-3)" "unprognostic (1.05e-1)" 21.0 1.5 5.7 3.3 1.8 0.4 7.4 0.5 2.1 5.4 6.8 6.7 1.1 8.0 1.4 3.0 5.4 9.6 4.3 1.9 6.9 1.5 0.6 15.9 2.3 0.9 2.3 14.2 4.0 1.2 0.3 40.1 1.0 11.0 2.2 1.1 1.6 4.1 1.7 4.1 2.2 9.0 0.6 2.0 2.6 3.4 2.7 0.5 3.0 1.5 0.8 9.3 4.0 0.5 8.1 13.1 69.5 0.2 90.5 112.2 1.1 48.6 34.0 40.8 50.8 15.2 3.1 0.0 0.1 76.9 4.6 6.9 4.8 4.6 55.9 28.4 0.1 3.6 4.8 0.3 41.3 0.5 0.2 86.6 7.6 60.1 26.9 21.8 6.1 0.1 0.0 0.1 51.5 0.1 0.5 0.4 1.4 0.1 0.3 0.1 91.7 0.4 0.0 8.3 0.2 0.1 20.8 0.7 0.1 2.4 0.2 0.3 2.8 90.3 13.4 518.3 1.6 0.2 0.2 0.0 16.8 0.0 3.8 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 5.7 1.8 0.5 2.1 1.9 6.9 0.9 2.3 1.0 0.6 2.7 0.5 2.5 3.2 2.2 0.0 0.0 8.0 11.1 2.1 4.0 0.0 0.9 4.6 1.2 1.5 3.3 11.0 0.0 35.6 0.1 0.0 0.0 13.4 138.1 1.3 31.0 1.7 0.0 0.0 0.4 2.6 178.1 33.4 1.1 1.2 0.0 0.1 2.5 0.0 7.5 0.0 2.0 0.0 2.0 0.0 10.3 71.8 132.3 0.7 3.6 6.5 0.0 17.1 0.0 0.0 1.4 13.2 0.0 149.3 0.0 17.7 0.0 0.1 3.2 0.3 13.1 65.9 21.8 1.1 1.4 1.8 5.3 80.7 0.5 23.1 0.0 4.5 WNT7A Wnt-7a ENSG00000154764 "Wnt family member 7A" O00755 3 13816258-13880071 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;gallbladder: 2.3;placenta: 2.7" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 68.7;Extravillous trophoblasts: 147.5;Pancreatic endocrine cells: 98.8;Syncytiotrophoblasts: 185.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.2;ovarian cancer: 11.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 1.7;naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cell line enhanced" "Detected in some" "BEWO: 59.8;EFO-21: 56.0;PC-3: 19.9;RPTEC TERT1: 100.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015719, CAB025894" Approved "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB025894: , HPA015719: AB_1858856" "unprognostic (1.26e-2)" "unprognostic (4.60e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (3.02e-1)" "unprognostic (1.14e-3)" "unprognostic (2.49e-1)" "unprognostic (3.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (7.89e-2)" "unprognostic (3.78e-2)" "unprognostic (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (3.74e-1)" "unprognostic (8.88e-3)" 0.0 0.0 3.6 0.1 3.1 0.1 0.0 1.0 3.7 0.2 0.3 0.0 0.0 1.1 0.2 0.4 0.1 2.3 0.0 2.4 2.1 0.2 0.0 2.0 0.2 5.1 1.9 0.0 0.1 0.0 0.0 2.7 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.0 3.4 1.3 0.0 1.3 2.5 0.0 0.0 0.0 0.1 0.3 0.1 2.8 8.6 0.0 0.8 0.0 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 7.6 0.0 56.0 0.0 0.1 11.2 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 1.7 100.3 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.6 3.1 1.0 3.7 2.4 2.1 5.1 1.9 2.5 3.4 2.5 2.8 0.0 12.8 0.0 8.5 0.0 5.9 2.8 2.6 0.0 0.0 0.0 0.0 0.7 8.6 1.4 0.0 0.0 68.7 0.0 0.0 0.0 13.8 17.3 14.5 0.4 0.6 0.0 0.0 4.0 9.1 147.5 0.4 0.0 17.9 0.0 0.0 0.0 0.0 7.4 0.0 2.4 0.0 0.0 0.0 0.0 5.6 0.0 0.1 0.0 1.0 0.0 0.0 0.0 4.5 0.3 98.8 0.0 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.2 6.0 2.3 0.0 1.3 185.7 1.5 0.0 0.0 6.0 XAGE2 "CT12.2, GAGED3, XAGE-2, XAGE2B" ENSG00000155622 "X antigen family member 2" Q96GT9 X 52369021-52375680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 199.5" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 1027.3;Extravillous trophoblasts: 1890.1;Syncytiotrophoblasts: 1367.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 96.3;SK-BR-3: 22.7;SuSa: 27.9;T-47d: 20.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (1.21e-1)" "unprognostic (9.67e-2)" "unprognostic (1.49e-1)" "unprognostic (4.47e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 5.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 199.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 96.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 4.3 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.7 1.2 27.9 20.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 38.5 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1027.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1890.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 107.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 1367.6 0.0 0.0 0.0 0.0 ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type palmitoyltransferase 16" Q969W1 10 97446170-97457370 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: AB_10794757, HPA040214: AB_2676886" "unprognostic (4.44e-2)" "unprognostic (3.14e-2)" "unprognostic (3.34e-1)" "unprognostic (1.20e-2)" "unprognostic (8.75e-2)" "unprognostic (8.35e-3)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (6.34e-2)" "unprognostic (1.93e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-1)" 15.6 14.9 17.8 10.2 18.5 6.8 16.3 20.3 21.9 15.0 16.4 17.1 14.3 16.4 18.5 19.9 12.2 9.9 22.1 18.1 16.5 25.1 30.3 20.8 11.3 17.2 17.8 15.9 22.8 25.5 16.7 21.6 16.4 18.3 17.3 17.4 24.2 12.1 25.8 13.1 14.7 16.6 16.1 14.5 24.1 17.3 18.8 12.6 16.0 27.9 15.1 17.1 15.3 16.7 50.7 57.4 37.9 47.1 58.7 40.4 38.7 54.6 72.1 61.2 58.4 45.7 43.6 44.4 60.1 79.8 53.4 58.0 48.2 76.7 54.2 43.7 56.0 28.5 39.8 44.3 47.4 34.0 39.7 45.7 49.8 71.6 51.3 66.3 63.9 40.4 23.1 32.8 79.0 48.4 51.8 46.0 29.9 45.8 49.5 34.0 38.6 40.9 51.9 23.2 18.4 25.9 33.2 33.7 30.6 37.7 44.6 32.9 39.6 38.2 35.0 25.0 64.7 29.2 53.0 26.9 44.1 51.7 20.7 0.3 11.1 11.1 7.2 11.9 8.1 9.0 12.5 11.5 15.7 10.6 10.0 10.1 0.5 14.5 11.8 12.0 11.1 6.8 17.8 18.5 20.3 21.9 18.1 16.5 17.2 17.8 16.4 16.1 18.8 16.7 6.2 19.2 23.1 3.9 9.0 5.2 18.9 31.8 14.8 15.8 13.6 9.3 10.1 14.3 27.6 12.9 4.2 39.8 10.3 11.5 25.4 35.5 24.8 7.0 13.3 11.3 7.2 11.6 8.2 32.3 67.2 13.7 10.2 10.9 7.0 13.3 7.5 19.5 24.6 13.5 9.2 18.9 28.5 7.3 5.9 7.6 8.7 9.3 3.6 9.4 18.4 14.9 15.5 11.1 8.4 31.5 12.1 3.8 17.1 20.0 18.9 22.2 8.3 13.0 6.6 5.2 12.2 20.1 12.9 13.8 4.3 37.9 7.2 10.9 20.9 19.3 ZFP42 "REX1, ZNF754" ENSG00000179059 "ZFP42 zinc finger protein" Q96MM3 4 187995771-188005046 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.1" "Group enriched" "Detected in some" 4 "Early spermatids: 44.8;Extravillous trophoblasts: 59.3" "Cancer enriched" "Detected in some" 41 "testis cancer: 40.5" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 13 "BEWO: 115.5;SuSa: 77.1" "Not detected" "Not detected" "Not detected" "Not detected" CAB025557 Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB025557: " "unprognostic (2.30e-1)" "unprognostic (1.07e-4)" "unprognostic (4.88e-3)" "unprognostic (3.75e-1)" "unprognostic (1.77e-1)" "unprognostic (3.86e-1)" "unprognostic (2.27e-1)" "unprognostic (4.66e-3)" 0.0 0.1 0.4 0.2 0.4 0.4 0.1 0.6 0.5 0.0 0.4 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.4 0.4 0.6 0.2 0.1 0.0 0.0 0.0 0.7 0.4 0.1 0.2 0.1 0.1 0.1 0.7 0.5 0.1 0.1 0.1 0.5 0.2 2.1 0.5 0.2 0.1 0.0 0.2 0.1 0.0 1.0 0.3 0.0 0.1 0.2 0.0 0.0 115.5 0.0 0.1 0.2 0.2 0.2 0.0 0.2 0.1 0.1 0.2 7.5 0.2 0.0 0.4 0.2 0.1 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.3 0.1 0.4 0.1 0.1 0.5 0.3 0.0 0.4 0.2 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.1 77.1 0.1 0.2 0.0 0.2 0.2 0.3 0.1 0.1 0.2 0.2 0.4 0.2 0.2 1.6 0.2 0.3 0.5 0.2 0.4 0.5 0.4 0.3 0.1 0.5 0.4 0.4 1.3 0.7 0.2 0.3 0.4 0.1 0.4 0.4 0.6 0.5 0.4 0.1 0.6 0.2 0.4 0.1 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 59.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 9.4 0.1 0.0 0.0 0.2