Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACP2 LAP ENSG00000134575 "Acid phosphatase 2, lysosomal" P11117 11 47239302-47248906 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 89.3;Hofbauer cells: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 69.9" "Lineage enriched" "Detected in all" 5 "monocytes: 69.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (5.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.86e-2)" "prognostic favorable (1.04e-4)" "unprognostic (7.90e-3)" "unprognostic (2.93e-1)" "unprognostic (6.16e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (3.28e-3)" "unprognostic (2.64e-3)" "unprognostic (5.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (8.68e-3)" "unprognostic (1.57e-1)" 25.2 36.6 17.3 22.9 17.1 6.4 21.8 17.0 18.5 16.5 22.1 23.3 42.9 15.8 29.8 14.3 14.1 19.6 21.7 19.8 26.0 27.4 80.5 21.4 29.4 20.8 19.6 11.1 45.9 21.3 21.3 28.7 23.1 25.4 18.1 11.9 50.3 18.3 14.0 11.4 31.9 16.9 16.9 29.1 24.8 12.2 22.0 13.7 19.3 14.8 15.3 22.0 13.1 17.2 16.5 33.5 31.9 28.2 28.1 13.6 24.4 26.6 47.1 47.5 49.4 23.3 26.3 4.3 21.9 34.2 14.3 23.7 16.9 24.6 22.5 85.5 29.1 11.1 48.1 24.6 38.4 16.4 27.1 34.1 15.2 24.6 14.5 28.3 34.9 14.1 20.3 33.9 31.5 26.8 13.4 14.2 21.5 24.8 20.0 10.8 43.1 36.2 34.9 37.6 16.7 26.0 36.8 80.1 19.2 16.3 49.0 14.0 21.0 23.9 19.8 31.4 38.4 28.1 40.0 3.6 35.0 8.2 37.6 12.5 16.9 7.2 12.3 69.9 9.4 2.5 7.6 11.1 15.1 1.5 6.6 5.7 2.8 9.7 48.2 0.6 8.3 10.9 17.3 17.1 17.0 18.5 19.8 26.0 20.8 19.6 23.1 16.9 22.0 17.2 13.3 19.2 18.6 6.2 5.6 4.1 9.3 42.2 10.2 14.4 13.5 9.1 9.2 21.5 29.4 18.4 6.2 41.3 2.6 37.6 9.8 50.6 1.8 7.7 15.6 18.3 15.0 13.5 6.9 60.1 33.3 15.3 17.3 12.1 12.0 10.7 45.7 89.3 113.5 11.8 8.9 26.7 22.4 80.0 3.9 3.5 5.0 33.8 24.9 3.7 29.8 20.6 7.2 8.5 4.3 33.5 29.5 10.5 21.1 10.9 55.3 33.4 19.2 11.9 19.7 8.1 14.5 11.8 19.1 9.5 2.4 29.3 5.8 25.2 14.3 8.6 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 174.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 426.9;Hofbauer cells: 426.7;Macrophages: 298.2;Proximal tubular cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 200.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 41.1;K-562: 30.4;RPMI-8226: 41.4;SK-MEL-30: 127.6;U-138 MG: 102.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" NA NA 4000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 9.4 6.0 2.2 42.4 3.9 9.4 25.6 2.5 21.4 34.7 3.0 46.4 31.9 19.2 7.8 23.4 8.6 26.7 5.1 1.9 3.9 74.0 32.5 174.1 87.1 4.1 3.1 20.3 11.9 2.4 1.3 13.3 6.0 19.6 36.4 20.1 14.3 7.0 1.4 24.9 30.2 13.3 4.1 43.5 38.7 4.0 15.7 25.4 3.0 5.0 43.6 33.1 11.3 5.7 10.2 1.1 0.0 0.2 0.5 0.0 41.1 1.1 25.8 0.0 0.1 0.4 0.3 1.4 1.8 9.0 5.9 0.3 0.0 4.5 0.1 12.1 0.8 0.3 0.0 5.0 1.4 0.1 0.6 0.0 4.1 0.4 0.0 0.0 0.0 0.0 30.4 0.2 0.0 2.3 0.9 1.4 0.8 0.3 0.7 0.4 1.8 41.4 0.0 0.4 0.7 1.0 0.0 0.0 127.6 1.1 0.2 0.4 0.9 102.9 1.2 1.8 0.3 0.7 5.7 0.6 23.7 0.1 4.0 0.4 35.3 76.6 15.8 36.1 8.8 200.1 26.0 19.6 7.3 110.9 35.3 20.2 10.4 13.3 36.3 62.5 67.8 36.4 2.2 3.9 2.5 21.4 1.9 3.9 4.1 3.1 6.0 4.1 15.7 5.7 2.2 9.6 7.8 0.0 75.7 10.3 11.0 21.8 25.0 18.3 14.6 18.4 1.4 15.7 5.7 7.3 18.8 33.4 21.2 7.0 9.8 1.8 0.2 0.7 9.1 30.9 3.0 24.5 0.0 11.3 32.7 19.8 10.7 0.9 63.7 0.8 426.9 8.4 426.7 1.7 0.0 4.7 10.2 106.0 68.6 0.7 1.8 298.2 14.2 1.0 79.8 48.5 8.2 0.0 0.1 4.4 20.4 12.0 33.4 14.5 12.7 145.8 2.5 41.4 0.0 0.4 2.8 0.1 0.2 14.6 11.1 26.1 29.5 0.1 6.7 6.1 ADAMDEC1 M12.219 ENSG00000134028 "ADAM like decysin 1" O15204 8 24384285-24406013 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 424.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 14.8;Kupffer cells: 12.9;Macrophages: 25.5;monocytes: 5.2" "Cancer enhanced" "Detected in all" "testis cancer: 16.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 8 "U-266/70: 10.7;U-266/84: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 28000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.17e-2)" "unprognostic (1.80e-2)" "unprognostic (4.15e-3)" "unprognostic (3.60e-1)" "unprognostic (6.21e-2)" "unprognostic (3.84e-3)" "unprognostic (2.12e-1)" "unprognostic (2.90e-1)" "unprognostic (1.61e-1)" "unprognostic (5.99e-3)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (1.74e-2)" "unprognostic (2.06e-1)" "unprognostic (1.35e-2)" "unprognostic (3.66e-2)" "unprognostic (8.23e-2)" 0.6 0.5 0.0 52.1 0.0 0.3 0.6 0.0 0.8 0.4 0.0 215.4 189.4 0.9 0.2 0.9 0.1 3.2 0.4 0.1 0.0 0.2 0.1 1.6 73.3 0.3 0.0 0.1 0.2 0.0 0.0 7.8 0.3 0.8 311.5 0.0 0.7 0.4 0.0 0.4 424.9 11.6 0.0 5.8 5.9 0.3 0.4 5.7 0.3 0.0 27.2 20.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 10.7 2.7 0.0 0.0 0.0 0.0 0.0 0.7 1.9 0.0 0.8 0.0 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.0 2.2 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.1 0.0 0.0 12.9 2.0 0.0 0.0 25.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 ADAP2 CENTA2 ENSG00000184060 "ArfGAP with dual PH domains 2" Q9NPF8 17 30906344-30959322 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.2;Hofbauer cells: 195.8;Kupffer cells: 186.8;Macrophages: 97.2;monocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 22.4;intermediate monocyte: 34.3;myeloid DC: 12.6;non-classical monocyte: 43.5" "Group enriched" "Detected in many" 9 "dendritic cells: 12.6;monocytes: 43.5" "Cell line enhanced" "Detected in some" "EFO-21: 7.0;HAP1: 17.6;HEK 293: 11.0;RPMI-8226: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (4.00e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.25e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.38e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-2)" 11.3 8.9 6.6 15.3 7.6 3.9 4.6 6.7 8.5 2.9 9.1 6.5 5.7 3.2 2.9 3.1 3.3 9.2 4.4 6.2 8.0 5.1 11.0 9.8 9.8 12.1 9.6 1.9 3.1 9.1 1.9 19.7 10.4 2.4 8.0 1.3 3.1 3.1 1.8 6.7 5.6 9.8 8.6 22.5 4.3 2.0 14.7 4.6 3.2 6.4 6.7 9.0 2.2 12.9 0.1 1.7 0.2 0.4 0.4 0.5 4.5 0.1 0.0 0.3 0.1 0.7 0.7 1.0 7.0 0.1 0.2 0.1 17.6 0.2 0.3 0.4 11.0 0.0 1.0 2.0 2.9 0.4 1.9 1.1 4.4 0.9 0.6 0.2 0.0 0.0 0.2 1.8 0.6 3.6 0.1 0.3 0.1 0.4 0.1 0.3 0.0 22.9 2.4 2.3 0.3 0.1 0.3 0.2 0.1 1.5 3.8 2.9 0.0 0.4 1.1 0.8 0.1 0.8 0.5 1.0 0.4 0.4 0.0 0.2 22.4 0.0 0.0 34.3 0.0 3.0 0.1 0.1 12.6 2.1 0.1 0.1 1.7 0.0 43.5 0.4 0.4 6.6 6.6 7.6 6.7 8.5 6.2 8.0 12.1 9.6 10.4 8.6 14.7 12.9 5.4 3.2 5.2 2.6 8.6 2.0 0.5 0.5 2.2 0.8 0.7 2.4 1.5 1.5 0.9 0.0 2.1 23.5 0.2 3.1 0.0 0.3 0.6 1.7 0.6 7.8 0.0 0.4 1.1 1.4 86.2 1.9 0.0 1.2 3.8 0.4 4.6 1.6 195.8 0.0 1.4 0.6 0.0 186.8 13.1 0.5 0.9 97.2 0.0 40.3 88.2 0.6 2.1 2.0 1.3 0.9 0.9 0.4 2.6 0.9 0.3 8.3 2.2 2.8 39.5 1.2 26.5 0.9 0.9 1.0 6.5 26.4 1.6 0.2 0.3 0.6 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 ADPRH ARH1 ENSG00000144843 "ADP-ribosylarginine hydrolase" P54922 3 119579268-119589945 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 23.9;HEL: 17.1;HMC-1: 18.5;Karpas-707: 25.3;U-266/70: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001701, HPA036961" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Nuclear membrane" Nucleoplasm "CAB001701: , HPA036961: AB_2675405" "prognostic favorable (2.42e-4)" "unprognostic (2.29e-1)" "unprognostic (4.77e-1)" "unprognostic (2.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.06e-2)" "unprognostic (2.63e-1)" "unprognostic (4.24e-2)" "unprognostic (3.31e-3)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (6.04e-2)" "unprognostic (2.60e-3)" "unprognostic (8.87e-2)" "unprognostic (2.03e-1)" "unprognostic (4.35e-2)" 10.6 6.2 3.0 7.3 3.3 3.4 7.9 3.3 4.2 6.9 9.2 5.5 2.3 6.0 4.9 4.0 4.2 6.9 8.5 2.9 3.5 4.9 3.1 13.5 11.0 4.6 3.4 1.9 6.7 8.0 2.0 11.3 4.4 6.1 4.1 6.6 5.1 9.3 11.8 2.6 5.4 9.2 4.2 11.9 3.9 2.4 4.6 5.9 5.8 9.9 13.0 6.5 3.4 4.9 2.4 3.0 0.7 0.0 2.4 2.7 0.0 2.1 0.4 1.8 2.3 0.9 2.0 0.6 0.9 3.2 0.1 0.2 2.0 0.0 1.7 23.9 0.2 17.1 0.4 0.0 3.9 0.1 18.5 4.0 0.1 0.9 0.1 0.8 7.3 0.0 1.6 25.3 11.0 0.7 0.0 4.1 6.9 0.2 5.8 0.0 8.2 1.1 1.0 0.9 0.5 0.1 0.0 0.1 6.4 1.0 4.4 10.6 6.0 0.0 1.1 4.6 0.4 24.5 5.8 0.1 3.0 0.0 4.6 13.9 18.7 19.1 0.8 17.2 0.8 11.0 1.9 1.7 11.2 6.8 0.2 0.7 0.6 5.3 13.9 9.8 14.3 7.5 3.0 3.3 3.3 4.2 2.9 3.5 4.6 3.4 4.4 4.2 4.6 4.9 12.6 9.6 8.6 0.3 5.0 0.8 0.7 0.4 0.0 0.5 1.5 1.9 4.7 2.8 2.7 3.7 4.2 5.8 5.0 0.3 1.9 3.6 0.7 0.2 0.9 9.9 0.0 2.7 0.1 3.2 3.8 2.1 2.6 0.5 10.8 2.5 7.1 1.6 9.4 0.0 0.2 0.2 2.0 12.2 11.1 0.5 0.3 14.8 1.8 4.7 10.2 0.8 4.1 0.0 0.6 2.1 0.5 3.0 3.9 0.7 0.0 1.3 2.1 4.3 0.0 3.6 3.9 0.4 0.6 0.1 0.9 11.8 1.2 0.7 0.2 0.2 AL159163.1 ENSG00000249141 "Novel protein" 6 166858094-166956124 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 3.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.3;Hofbauer cells: 4.6;Pancreatic endocrine cells: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NB-4: 4.7;OE19: 6.2;U-937: 2.6" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.22e-1)" "unprognostic (1.22e-1)" "unprognostic (7.52e-2)" "unprognostic (7.60e-2)" "unprognostic (1.51e-2)" "unprognostic (4.47e-2)" "unprognostic (7.13e-3)" "unprognostic (1.87e-1)" "unprognostic (2.27e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.90e-3)" "unprognostic (1.76e-10)" "unprognostic (2.10e-1)" "unprognostic (1.24e-3)" "unprognostic (1.52e-1)" "unprognostic (9.28e-3)" 0.5 0.6 1.1 0.4 1.6 0.6 0.3 0.2 1.1 0.8 0.2 2.6 1.0 0.2 2.1 0.5 0.0 1.0 0.0 1.0 1.0 0.2 0.4 0.4 1.0 0.7 0.9 0.0 3.5 0.1 0.4 0.4 0.6 0.1 2.1 0.4 1.5 0.1 0.4 0.3 0.4 0.6 0.7 1.0 1.3 0.2 1.5 0.1 0.2 0.0 1.7 0.4 0.1 0.9 0.3 0.0 0.7 0.4 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.6 1.1 0.2 0.0 0.6 0.6 0.5 1.1 0.4 1.2 0.0 0.6 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.3 1.0 4.7 0.1 6.2 0.0 0.0 0.0 1.2 1.5 0.2 0.2 0.5 0.0 2.5 0.0 0.5 0.2 1.0 0.0 0.0 0.6 2.4 0.0 0.9 1.9 0.0 0.7 2.6 0.0 1.7 3.5 0.2 0.5 5.0 0.8 0.9 1.8 0.6 5.5 1.8 1.1 0.2 1.6 0.2 7.9 5.5 2.1 1.7 1.1 1.6 0.2 1.1 1.0 1.0 0.7 0.9 0.6 0.7 1.5 0.9 0.1 0.0 1.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.0 0.7 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 660000 "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-3)" "unprognostic (1.60e-1)" "prognostic favorable (7.24e-6)" "unprognostic (1.85e-2)" "unprognostic (3.78e-2)" "unprognostic (2.94e-2)" "unprognostic (3.76e-2)" 30.7 46.7 38.0 47.2 38.3 45.8 26.4 37.3 45.2 22.8 35.6 34.9 43.3 22.7 12.1 63.0 23.5 30.4 23.9 36.1 40.8 34.8 34.8 30.1 57.8 44.2 44.6 17.5 38.3 67.0 39.2 44.8 43.7 38.3 30.1 35.3 40.3 25.9 24.5 47.2 45.6 27.1 41.4 52.6 40.9 24.7 52.7 34.2 29.6 20.5 54.4 39.4 32.2 48.8 84.6 47.5 49.3 50.2 37.0 27.0 60.0 59.8 65.5 71.2 68.2 74.4 33.2 46.1 37.2 68.4 33.0 74.6 71.5 97.6 45.2 58.2 102.0 79.1 60.8 42.0 38.9 114.1 99.9 38.6 36.0 67.5 55.0 33.0 98.7 17.2 54.6 54.9 48.3 93.7 45.5 36.8 37.3 124.8 53.3 89.0 54.3 119.9 50.2 194.5 75.9 52.2 74.0 82.5 36.4 33.5 66.7 49.5 84.6 79.1 48.8 46.0 62.1 60.4 32.5 84.6 56.1 48.1 46.7 0.0 29.3 5.7 9.2 29.2 9.1 16.2 6.3 7.9 28.7 18.2 4.9 5.2 3.0 7.2 31.7 9.0 8.8 24.2 38.0 38.3 37.3 45.2 36.1 40.8 44.2 44.6 43.7 41.4 52.7 48.8 17.8 12.8 16.4 27.7 53.0 7.1 9.3 16.7 16.5 26.3 26.2 20.8 16.1 21.5 16.4 22.0 39.6 52.3 15.1 69.6 23.5 41.2 7.5 16.4 11.6 19.8 21.6 40.0 24.1 40.7 30.1 12.1 33.6 30.1 5.1 13.2 35.3 34.3 138.9 45.4 25.6 24.9 18.3 95.5 24.2 13.1 11.8 65.7 12.4 51.5 29.8 28.4 9.2 16.1 14.0 65.9 33.2 12.4 28.5 17.5 51.2 30.1 14.5 42.1 6.6 17.8 12.7 23.5 17.6 33.0 9.1 68.3 17.0 39.6 36.2 18.1 AP2A2 "ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899" ENSG00000183020 "Adaptor related protein complex 2 subunit alpha 2" O94973 11 924894-1012245 "Plasma proteins, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017514, HPA043040" Supported Supported Nucleoplasm,Vesicles NA NA 10000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "CAB017514: AB_2056344, HPA043040: AB_2678283" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.09e-2)" "unprognostic (1.28e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (9.27e-5)" "unprognostic (1.34e-2)" "unprognostic (4.09e-1)" "unprognostic (1.70e-1)" "prognostic favorable (4.57e-4)" "unprognostic (2.41e-1)" "unprognostic (2.86e-3)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (1.40e-1)" "unprognostic (2.08e-2)" 20.1 18.0 3.5 1.3 5.1 4.5 16.6 10.8 9.9 20.3 1.4 23.0 5.4 17.9 1.5 12.7 18.1 2.0 19.1 5.5 3.5 34.4 29.9 18.9 3.2 0.9 2.1 17.5 25.3 3.7 25.6 5.2 3.0 20.3 4.9 5.8 14.6 4.0 14.1 14.5 19.6 5.6 0.0 57.6 20.6 15.5 3.3 3.8 13.9 1.6 2.5 19.0 15.7 1.4 7.5 2.9 3.7 10.7 13.8 14.2 9.1 10.2 3.3 6.0 4.9 1.3 7.3 7.4 8.7 12.3 5.7 8.9 8.9 5.6 3.9 5.5 23.2 2.1 10.4 3.9 5.3 2.8 4.9 16.8 6.1 3.1 6.1 14.8 8.5 5.0 5.9 4.7 6.3 0.4 2.6 3.2 2.0 9.1 17.9 4.2 2.6 8.1 9.2 6.2 12.3 10.0 11.4 9.2 1.7 6.3 5.4 0.8 13.3 1.9 2.3 2.8 5.2 4.3 3.9 5.3 4.0 3.7 3.1 1.5 1.7 1.5 1.1 1.7 0.5 0.5 1.1 0.6 1.4 1.0 1.1 1.2 2.1 1.1 1.4 1.3 2.1 0.6 3.5 5.1 10.8 9.9 5.5 3.5 0.9 2.1 3.0 0.0 3.3 1.4 38.1 38.5 21.8 29.4 14.3 14.3 12.4 13.3 7.4 50.9 27.2 23.0 12.9 21.5 15.9 62.5 60.5 42.1 17.3 45.3 39.2 37.5 46.7 64.0 44.6 36.6 35.2 27.1 37.2 18.0 45.2 28.7 16.3 86.7 27.3 31.0 80.3 59.8 82.8 101.0 36.4 32.3 18.3 104.7 26.9 28.3 34.5 51.8 8.8 41.2 31.2 30.4 39.1 23.1 21.9 25.8 24.2 27.8 13.6 16.9 43.5 70.4 23.5 69.2 26.3 20.7 22.6 72.7 28.0 11.2 11.4 28.5 19.7 30.5 37.0 11.5 AP2S1 "CLAPS2, FBH3, FBHOk, HHC3" ENSG00000042753 "Adaptor related protein complex 2 subunit sigma 1" P53680 19 46838136-46850846 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 991.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.34e-1)" "unprognostic (5.93e-2)" "unprognostic (9.89e-2)" "unprognostic (1.97e-1)" "unprognostic (1.30e-1)" "unprognostic (6.60e-2)" "unprognostic (4.86e-3)" "unprognostic (1.11e-2)" "unprognostic (9.54e-2)" "unprognostic (2.19e-1)" "unprognostic (5.25e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (5.79e-2)" "unprognostic (3.56e-1)" "unprognostic (3.07e-1)" "unprognostic (6.05e-2)" 120.2 136.5 110.7 80.6 119.9 126.5 95.9 104.9 138.5 83.0 99.6 91.5 67.3 62.1 41.0 188.9 58.6 46.1 107.5 122.1 117.7 106.8 148.9 90.2 62.4 108.0 103.9 52.3 77.2 51.9 72.4 79.1 111.9 90.8 57.4 27.6 99.8 48.8 101.6 125.8 79.8 60.1 106.0 124.6 85.1 69.2 111.3 67.2 61.5 63.7 67.6 82.9 103.4 112.5 380.3 363.2 181.6 198.7 227.1 248.7 122.2 311.0 383.2 349.2 411.0 277.1 189.3 121.1 168.6 476.2 153.6 178.8 144.9 450.6 263.9 115.1 418.6 210.4 220.6 204.0 306.7 142.1 150.0 317.9 259.0 337.9 281.1 259.0 471.1 199.5 186.1 180.4 331.1 403.2 181.1 1060.2 295.7 341.8 268.8 142.8 167.0 170.8 269.2 299.9 177.2 258.8 239.1 298.4 377.0 113.9 248.6 336.4 343.2 246.0 293.8 135.3 375.7 130.8 302.0 134.8 439.0 292.3 437.6 278.6 640.3 406.6 174.3 708.8 145.2 211.5 167.3 174.5 716.8 198.4 153.1 156.3 204.6 188.5 544.6 431.5 233.8 673.1 110.7 119.9 104.9 138.5 122.1 117.7 108.0 103.9 111.9 106.0 111.3 112.5 129.0 38.5 57.2 10.4 85.9 171.6 103.9 341.6 73.4 39.5 179.0 227.8 79.4 137.2 163.9 95.6 16.7 415.2 100.9 397.7 348.3 215.6 80.7 67.8 106.7 190.6 163.7 250.7 14.6 247.2 257.4 130.2 95.8 82.5 92.7 176.1 396.9 308.4 991.6 45.4 13.3 259.6 164.8 515.0 389.5 232.8 92.6 389.5 200.9 4.7 661.1 109.4 160.6 4.5 14.8 249.8 333.9 95.5 94.8 157.6 442.9 432.4 89.0 42.5 98.6 59.1 173.9 78.9 52.5 252.2 253.3 440.5 87.9 230.6 282.1 164.3 AP5B1 "AP-5, DKFZp761E198, PP1030" ENSG00000254470 "Adaptor related protein complex 5 subunit beta 1" Q2VPB7 11 65773898-65780976 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 44.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "neutrophil: 25.0" "Lineage enriched" "Detected in many" 14 "granulocytes: 25.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065739, HPA067880" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Golgi apparatus" "HPA065739: AB_2685550, HPA067880: AB_2685914" "unprognostic (3.64e-1)" "unprognostic (9.40e-2)" "unprognostic (4.37e-3)" "unprognostic (1.45e-2)" "unprognostic (5.56e-3)" "unprognostic (1.09e-2)" "unprognostic (1.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.25e-1)" "unprognostic (2.15e-1)" "prognostic favorable (2.31e-5)" "unprognostic (2.03e-2)" "unprognostic (2.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.67e-1)" 8.3 4.8 3.2 6.9 2.6 44.0 6.6 5.8 3.6 5.4 1.3 6.0 5.7 7.1 2.0 10.2 5.2 3.1 5.0 3.6 1.2 5.7 5.8 8.7 4.7 3.9 1.5 2.9 10.3 6.4 3.5 3.8 3.0 5.0 3.0 2.5 7.0 4.5 9.6 9.1 6.8 3.2 1.1 10.0 6.0 2.5 1.8 4.8 4.9 3.4 4.3 6.6 5.1 1.6 12.8 9.8 2.8 14.3 8.6 4.1 16.4 5.3 6.2 6.1 4.7 7.7 6.0 7.8 9.4 6.3 12.4 15.8 8.7 4.3 2.9 12.1 10.1 7.0 12.0 3.8 5.8 9.9 13.3 7.0 10.1 4.0 2.9 6.0 5.2 13.6 15.6 9.7 3.6 9.2 5.5 10.5 4.6 4.4 10.1 17.3 0.5 16.8 5.9 15.8 2.7 5.4 4.1 2.6 26.0 3.7 4.4 14.1 7.6 10.2 8.6 13.6 6.0 10.0 11.2 8.1 7.5 8.5 10.5 1.1 1.7 0.6 0.5 1.0 0.2 0.3 0.2 0.2 0.5 0.3 0.3 0.2 25.0 0.4 1.3 0.3 0.2 0.8 3.2 2.6 5.8 3.6 3.6 1.2 3.9 1.5 3.0 1.1 1.8 1.6 2.0 0.0 8.8 6.2 3.9 2.4 12.3 4.3 7.4 5.0 4.2 2.0 1.6 2.8 3.7 7.3 14.6 7.6 5.9 12.8 1.9 8.9 1.4 6.3 2.9 3.0 3.0 0.0 3.6 13.6 18.2 2.9 6.6 10.7 2.5 5.3 1.4 7.1 14.0 11.8 3.2 3.8 6.1 12.4 2.1 0.7 0.6 11.6 7.2 3.7 17.8 3.0 6.2 1.0 2.2 9.4 6.9 3.8 3.6 5.6 10.1 8.8 2.9 8.0 0.0 3.7 3.0 0.6 4.7 6.0 2.3 34.9 4.3 2.0 4.5 10.0 ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 262.0;Kupffer cells: 242.5;Langerhans cells: 164.2;Macrophages: 226.4;monocytes: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 195.8;HMC-1: 315.9;NB-4: 199.2;U-937: 279.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" 48.6 39.7 54.4 110.0 53.8 263.6 26.1 48.2 62.2 19.3 49.1 29.5 50.5 17.4 10.8 15.1 29.0 31.4 25.0 63.8 67.7 25.2 35.6 94.8 59.4 61.6 58.3 17.5 19.4 16.4 24.9 35.5 59.5 19.5 27.6 16.9 20.9 11.7 12.7 14.6 51.1 29.6 55.4 168.3 35.0 7.2 59.5 45.2 15.8 18.1 38.0 41.6 17.6 66.5 17.3 88.7 34.7 32.9 6.8 9.5 18.6 13.7 18.0 38.4 48.0 31.0 14.2 49.1 12.2 10.3 18.3 28.5 58.0 18.4 39.4 116.6 85.0 195.8 46.8 55.6 10.2 89.2 315.9 8.8 23.5 47.9 18.7 24.9 29.6 89.1 13.5 46.4 8.9 30.5 87.9 199.2 18.9 44.9 18.4 104.3 31.0 53.8 13.2 9.2 36.0 49.2 30.8 50.8 23.6 14.2 24.6 40.0 26.1 14.3 29.1 25.1 51.5 19.8 28.6 27.6 37.9 279.4 21.6 116.2 145.5 269.7 49.1 151.1 35.1 10.1 31.1 51.3 84.9 9.0 29.3 38.7 250.6 29.9 168.6 20.7 28.8 93.5 54.4 53.8 48.2 62.2 63.8 67.7 61.6 58.3 59.5 55.4 59.5 66.5 7.7 22.4 32.3 5.5 26.4 11.5 7.7 16.6 3.4 20.5 9.6 12.3 8.3 14.3 47.9 3.7 2.1 7.5 83.8 7.4 15.6 11.2 0.6 1.5 3.6 10.1 8.4 33.9 20.4 7.3 12.0 8.7 19.4 1.8 94.9 7.8 19.2 12.4 262.0 21.9 18.2 17.0 50.8 242.5 164.2 3.5 5.0 226.4 10.6 42.2 311.3 5.8 89.6 7.1 8.4 6.3 22.0 4.9 23.4 4.4 35.5 17.5 24.4 8.7 19.7 10.9 8.5 1.1 13.1 6.8 8.4 6.0 77.2 3.5 11.4 11.7 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ATP6AP1 "16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3" ENSG00000071553 "ATPase H+ transporting accessory protein 1" Q15904 X 154428633-154436516 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015218 Uncertain NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "CAB015218: " "prognostic unfavorable (2.40e-4)" "unprognostic (1.95e-2)" "unprognostic (2.06e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (1.84e-3)" "unprognostic (4.99e-3)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" "unprognostic (1.84e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.07e-1)" "prognostic favorable (5.26e-8)" "unprognostic (2.45e-1)" "unprognostic (4.66e-2)" "unprognostic (3.39e-1)" "unprognostic (1.62e-1)" 56.3 93.5 108.3 43.1 109.2 59.1 56.7 99.6 118.0 59.6 123.6 61.5 48.4 54.2 145.1 85.2 60.0 46.0 92.7 116.2 115.4 104.3 51.4 96.8 46.9 114.0 96.8 63.3 86.6 176.0 110.4 77.9 121.6 85.1 57.0 74.0 87.4 54.8 53.8 83.6 57.4 49.0 104.6 94.7 70.4 47.5 104.2 40.9 81.9 54.4 42.5 63.7 60.9 121.6 110.1 101.6 88.2 146.2 145.7 77.4 162.2 78.5 116.6 122.5 176.1 93.4 135.1 64.7 337.8 177.1 216.5 112.3 133.8 71.9 76.6 58.6 135.1 37.5 113.7 100.0 170.6 60.9 260.2 98.1 126.7 112.4 68.2 139.5 177.0 47.8 45.6 176.4 84.7 158.1 43.6 96.8 32.1 171.0 100.8 66.6 59.1 170.7 139.9 87.3 84.6 89.7 72.6 289.7 159.3 87.3 123.1 157.8 135.5 87.4 79.0 151.1 135.6 256.3 311.8 77.0 104.4 132.8 90.2 246.6 295.1 363.9 147.3 313.8 148.6 91.7 118.4 127.8 376.7 113.6 107.1 117.8 326.9 140.3 255.6 215.9 155.2 216.9 108.3 109.2 99.6 118.0 116.2 115.4 114.0 96.8 121.6 104.6 104.2 121.6 39.4 38.5 57.5 17.0 32.3 30.2 42.7 122.4 25.6 105.8 58.5 42.2 37.7 54.3 102.1 97.5 47.9 145.1 40.1 84.3 19.6 65.4 3.1 52.5 33.7 50.1 89.0 35.8 17.0 52.5 104.5 48.8 36.7 57.4 77.3 51.8 54.3 46.6 246.3 129.5 24.2 59.0 160.7 143.6 88.2 5.5 41.3 130.3 72.9 15.0 79.9 68.4 27.8 22.1 26.4 42.4 67.5 42.5 61.7 34.1 63.7 49.1 112.5 69.2 65.7 35.7 45.5 64.4 10.7 31.6 32.8 196.5 36.3 74.1 54.6 47.2 ATP6AP2 "APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR" ENSG00000182220 "ATPase H+ transporting accessory protein 2" O75787 X 40579372-40606848 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Congenital disorder of glycosylation, Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 765.1" "Cell type enhanced" "Detected in all" "Hofbauer cells: 702.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003156 Approved NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA003156: AB_1078245" "unprognostic (1.45e-1)" "unprognostic (3.80e-3)" "unprognostic (1.30e-1)" "unprognostic (7.19e-2)" "unprognostic (8.58e-3)" "unprognostic (1.29e-1)" "unprognostic (1.63e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-1)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.01e-5)" "unprognostic (2.34e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-2)" "unprognostic (2.86e-2)" 81.2 71.5 85.6 60.6 86.5 124.4 95.1 76.4 116.9 106.1 72.4 82.9 32.1 86.6 91.3 70.1 75.6 79.7 55.1 90.8 90.2 165.6 96.8 87.3 67.4 80.4 79.8 68.9 53.3 765.1 30.7 106.9 83.4 86.6 89.0 99.3 39.4 97.9 18.4 71.9 47.8 124.7 84.6 69.0 49.1 40.4 87.6 72.0 177.1 40.1 72.5 97.7 41.4 98.7 83.9 117.5 78.7 106.7 472.6 312.4 47.9 182.4 274.1 127.0 152.9 68.0 142.6 48.4 88.1 257.0 141.3 86.6 114.0 136.0 168.2 92.7 97.7 57.5 100.2 66.5 172.0 104.6 111.6 259.6 175.2 154.2 121.4 200.3 168.1 46.1 63.8 130.7 201.7 109.8 45.5 93.7 73.4 140.8 112.7 43.8 132.6 161.6 182.8 96.8 55.2 51.9 185.8 111.7 118.4 284.2 147.8 97.1 172.5 175.0 91.3 207.7 62.8 38.0 70.7 46.2 139.1 93.0 138.5 269.0 511.1 404.8 156.1 364.9 164.3 106.7 157.3 161.9 341.3 110.3 174.8 159.3 255.9 141.2 378.6 124.2 167.2 692.9 85.6 86.5 76.4 116.9 90.8 90.2 80.4 79.8 83.4 84.6 87.6 98.7 102.3 57.7 65.6 36.2 65.4 97.3 135.4 254.3 46.1 155.8 74.1 61.2 30.4 94.4 175.4 138.0 54.2 173.4 109.6 70.3 62.6 146.6 3.6 97.2 115.5 94.7 57.1 62.3 44.8 59.1 106.3 156.5 34.7 124.5 87.5 63.7 96.0 64.0 702.2 188.4 56.3 54.6 349.9 279.5 263.3 9.5 117.4 222.0 149.4 28.1 185.4 193.0 72.1 40.2 40.6 64.0 58.9 151.2 74.8 97.9 61.0 106.4 127.4 93.3 105.2 116.7 138.7 106.7 43.1 60.0 99.9 174.4 100.3 188.2 63.6 121.1 ATP6V0D1 "ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD" ENSG00000159720 "ATPase H+ transporting V0 subunit d1" P61421 16 67438014-67481181 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 380.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016938 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA016938: AB_1845191" "unprognostic (1.12e-2)" "unprognostic (1.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.79e-3)" "unprognostic (8.57e-2)" "unprognostic (2.93e-1)" "unprognostic (1.20e-2)" "unprognostic (8.30e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.20e-5)" "unprognostic (5.72e-3)" "prognostic favorable (1.76e-8)" "unprognostic (2.72e-1)" "unprognostic (6.42e-2)" "unprognostic (2.63e-2)" "unprognostic (4.33e-3)" 51.3 112.9 103.1 66.9 107.1 82.3 50.3 84.1 118.4 65.2 82.4 89.8 69.0 69.2 56.6 88.6 57.8 55.9 71.5 119.9 145.1 86.2 73.0 78.7 66.9 112.6 107.4 35.1 59.2 116.3 107.7 55.8 136.0 60.5 72.7 41.4 62.8 55.0 127.6 85.9 79.9 79.6 82.6 96.1 69.4 69.5 99.4 64.7 75.1 84.7 64.0 66.8 62.2 98.5 78.9 111.6 67.3 87.5 167.2 91.2 64.3 92.7 149.1 187.0 224.3 116.5 82.6 33.0 74.2 134.7 125.3 91.9 99.0 117.7 108.8 40.3 90.5 60.5 58.4 97.6 159.4 60.5 243.3 139.8 115.1 187.4 44.5 68.2 117.9 38.0 69.7 41.9 151.9 193.7 45.7 134.9 65.2 70.6 77.9 80.2 78.5 92.1 113.3 129.3 130.4 60.4 244.0 65.8 103.1 52.3 104.8 91.1 114.4 93.4 38.6 113.9 49.8 69.5 106.8 94.9 130.1 63.8 56.3 312.7 732.5 542.4 130.1 511.7 89.9 189.4 96.3 120.3 469.2 174.5 73.1 91.3 936.5 155.5 485.5 168.4 128.0 742.7 103.1 107.1 84.1 118.4 119.9 145.1 112.6 107.4 136.0 82.6 99.4 98.5 46.0 16.0 47.2 11.1 80.1 73.8 61.5 138.2 45.5 73.3 65.7 50.5 38.8 54.3 78.0 68.0 73.0 112.1 74.7 258.8 181.9 127.7 109.6 93.3 46.4 42.6 121.9 68.8 22.7 111.0 73.1 61.5 68.3 74.5 50.1 44.2 42.5 50.2 380.4 82.4 25.7 160.2 154.6 149.4 186.7 50.1 58.7 183.1 124.5 7.5 260.9 70.6 77.2 13.6 23.1 102.0 179.5 53.0 57.0 38.8 203.1 173.6 92.7 52.9 118.3 26.6 53.2 125.7 64.0 55.0 87.5 283.6 54.7 91.3 101.6 63.2 ATP6V1F "ATP6S14, VATF, Vma7" ENSG00000128524 "ATPase H+ transporting V1 subunit F" Q16864 7 128862856-128865847 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1054.6;Hofbauer cells: 1132.8;Proximal tubular cells: 1076.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009529, HPA048700, HPA062011" Supported NA NA 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" "CAB009529: AB_2290237, HPA048700: AB_2680498, HPA062011: AB_2684656" "unprognostic (1.70e-1)" "unprognostic (1.61e-2)" "unprognostic (2.14e-2)" "unprognostic (3.26e-2)" "unprognostic (2.99e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.28e-3)" "unprognostic (2.70e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "prognostic favorable (2.49e-5)" "unprognostic (2.20e-1)" "unprognostic (2.43e-1)" "unprognostic (1.36e-2)" "unprognostic (7.33e-2)" 133.3 160.7 275.6 106.2 290.1 210.4 122.3 272.7 368.6 126.5 250.2 104.6 74.7 95.3 61.7 223.0 98.3 104.2 183.3 294.8 300.1 307.0 84.2 140.0 139.9 280.1 275.3 89.0 106.8 163.5 141.0 104.6 286.0 103.0 56.6 110.6 129.3 81.6 169.3 170.1 97.0 71.2 269.5 119.6 114.4 212.2 284.3 119.6 84.6 154.7 103.7 123.1 146.6 277.4 305.6 345.1 151.2 323.2 297.6 236.8 86.9 151.2 201.3 246.8 267.2 257.0 179.8 287.6 156.5 175.7 367.7 163.9 224.5 250.1 91.9 312.6 364.2 220.1 211.4 256.4 344.1 227.1 400.8 278.2 340.0 284.7 163.4 188.9 238.1 257.9 534.3 297.3 276.3 403.1 381.0 494.3 201.9 190.6 281.4 168.7 110.1 467.5 315.5 240.3 286.6 197.3 214.1 796.5 363.7 156.6 184.4 284.9 253.0 303.5 65.3 409.5 236.2 333.5 326.9 372.0 600.4 315.5 263.6 370.2 697.1 489.2 244.6 475.1 238.0 343.7 247.6 239.7 508.9 348.5 235.8 238.6 203.1 243.6 324.7 288.3 317.3 886.1 275.6 290.1 272.7 368.6 294.8 300.1 280.1 275.3 286.0 269.5 284.3 277.4 129.3 28.9 62.8 17.3 140.1 237.6 202.5 378.9 136.6 111.4 162.0 190.1 157.6 127.2 230.7 331.1 37.5 171.8 119.8 97.3 1054.6 241.0 574.0 128.6 96.3 163.1 113.2 63.1 27.0 222.2 289.0 155.1 78.5 131.0 275.1 114.0 124.6 112.0 1132.8 545.1 34.6 108.7 585.9 320.6 378.7 898.9 164.4 456.1 254.3 16.9 285.8 230.4 190.5 11.6 26.2 253.9 93.0 127.9 136.8 224.7 212.0 1076.3 200.2 96.4 85.5 69.7 168.9 399.6 102.0 328.4 326.6 401.4 136.3 184.5 98.9 362.7 ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "bone marrow: 78.1" "Cell type enriched" "Detected in many" 6 "Microglial cells: 248.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.2;NK-cell: 11.0" "Group enriched" "Detected in many" 5 "granulocytes: 15.2;NK-cells: 11.0" "Cell line enhanced" "Detected in some" "HMC-1: 40.2;NB-4: 19.2;THP-1: 26.7;U-937: 103.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040254 Approved Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" 1.4 1.1 2.3 2.5 2.4 78.1 0.7 3.5 6.5 1.5 3.0 1.1 0.7 6.4 4.2 0.5 3.1 2.2 0.4 4.5 2.9 1.2 1.6 1.1 1.0 2.5 2.6 0.4 0.5 0.2 0.3 3.5 2.8 0.6 1.7 0.1 0.5 0.8 0.1 0.3 1.3 3.1 3.1 2.6 0.6 0.4 2.4 0.5 0.1 0.1 1.0 1.4 0.4 4.9 0.1 0.6 0.0 0.0 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.5 0.5 0.2 0.0 0.2 12.2 0.0 7.3 1.7 0.1 0.0 13.6 40.2 0.7 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 19.2 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.1 1.2 0.0 0.0 0.1 0.0 26.7 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 1.3 103.7 0.0 15.2 2.0 3.8 0.4 1.2 0.1 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.8 11.0 0.4 0.0 0.0 0.9 2.3 2.4 3.5 6.5 4.5 2.9 2.5 2.6 2.8 3.1 2.4 4.9 1.7 0.0 1.9 1.6 0.8 1.5 0.1 0.2 0.6 0.6 0.2 0.6 1.3 0.0 0.1 0.0 0.0 5.4 12.5 0.3 0.0 0.0 27.6 0.3 1.7 1.0 0.0 12.2 20.3 0.0 1.8 8.1 3.1 0.2 19.7 0.0 1.1 3.7 16.4 0.0 17.5 0.3 2.0 37.0 17.7 25.3 1.8 27.0 1.8 248.3 6.3 0.5 15.5 1.0 2.1 0.0 0.1 0.7 4.8 2.3 0.7 1.2 0.7 0.2 0.0 1.0 7.0 0.5 0.6 0.6 0.3 2.9 13.4 1.1 0.2 0.3 B3GAT3 GlcAT-I ENSG00000149541 "Beta-1,3-glucuronyltransferase 3" O94766 11 62615296-62622154 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051328 Approved "Intracellular and membrane" NA NA 990000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA051328: AB_2681444" "unprognostic (1.55e-1)" "unprognostic (3.93e-2)" "unprognostic (8.45e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.11e-6)" "unprognostic (4.94e-2)" "unprognostic (2.42e-1)" "unprognostic (3.66e-2)" "unprognostic (1.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.58e-3)" "unprognostic (1.46e-3)" "unprognostic (6.00e-2)" "unprognostic (4.48e-2)" "unprognostic (2.58e-2)" 28.2 30.0 63.4 17.0 63.8 18.2 27.4 67.0 81.8 33.7 65.9 27.8 17.2 30.0 11.5 21.0 30.0 15.3 23.1 64.0 66.7 52.1 48.7 29.0 26.2 72.3 64.3 32.3 30.7 19.1 55.7 19.1 76.5 37.1 6.9 16.0 25.9 18.2 14.3 33.9 27.8 14.0 63.3 40.0 28.9 23.9 67.1 18.5 30.1 6.8 10.8 30.5 25.7 69.7 36.0 57.3 32.0 55.0 40.0 38.7 23.4 28.3 38.9 26.7 29.4 25.4 52.3 33.4 91.1 29.5 70.6 24.5 30.8 28.7 6.2 71.5 61.3 17.0 25.9 32.8 96.8 21.4 34.8 69.1 47.6 35.0 15.3 42.4 25.3 37.9 51.5 76.7 33.9 89.1 38.1 76.7 47.5 18.9 55.1 36.7 22.5 175.4 55.0 7.2 33.6 53.1 32.6 38.2 134.6 10.6 52.9 41.6 18.6 28.6 20.8 75.2 54.4 79.3 28.7 37.6 82.3 41.0 56.0 32.0 29.3 27.4 21.6 31.8 14.0 18.5 14.9 17.7 25.8 15.3 14.8 17.2 8.6 41.0 33.8 15.5 19.9 16.4 63.4 63.8 67.0 81.8 64.0 66.7 72.3 64.3 76.5 63.3 67.1 69.7 33.2 6.4 13.2 22.2 36.8 19.8 39.0 53.3 51.2 52.3 33.1 44.4 4.2 31.5 26.1 40.5 33.3 77.0 45.3 26.5 15.6 33.8 0.4 20.0 36.3 22.8 25.2 24.4 19.1 46.3 61.3 34.8 25.5 24.1 1.3 45.3 23.2 28.4 67.8 48.8 25.3 23.9 57.0 35.2 17.5 3.2 36.1 34.4 44.4 8.4 45.3 52.5 49.4 14.6 19.5 36.4 31.2 22.6 51.0 30.6 27.3 16.2 15.2 49.6 26.3 22.3 33.7 6.8 25.8 21.9 19.5 43.5 41.7 31.9 28.3 21.0 BCKDK ENSG00000103507 "Branched chain keto acid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 95.9;granulocytes: 89.7;monocytes: 115.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA017995: AB_1845309, HPA056067: AB_2683024" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 32.3 56.4 18.4 19.2 18.6 14.5 29.0 17.4 23.8 25.1 18.0 31.4 16.0 27.7 16.7 29.4 24.8 17.9 78.6 18.8 17.8 43.8 76.4 21.7 15.6 20.6 20.7 27.5 70.5 22.9 16.4 15.3 19.3 29.3 12.5 6.3 47.0 21.8 81.3 45.4 24.1 19.5 17.1 30.2 42.0 17.4 18.5 9.8 22.4 69.7 13.6 30.2 24.6 17.5 47.5 49.1 27.1 41.8 32.8 32.5 31.1 40.4 46.3 57.3 55.9 32.1 29.1 41.5 58.9 47.5 28.0 31.4 19.3 65.6 36.5 34.4 60.1 45.2 32.6 59.5 57.5 23.5 41.9 48.3 26.2 49.2 40.6 52.6 62.4 31.1 23.4 39.4 87.7 75.8 22.9 32.4 23.0 20.5 39.1 45.8 39.6 78.8 44.3 30.1 42.1 38.7 31.3 72.4 24.6 22.9 44.5 24.6 41.1 44.2 26.1 45.8 32.2 44.5 15.7 15.1 50.3 33.7 42.6 58.1 115.0 85.2 17.7 97.6 17.2 22.8 16.5 13.9 95.9 19.0 13.6 16.1 89.7 22.8 71.2 19.3 24.5 53.1 18.4 18.6 17.4 23.8 18.8 17.8 20.6 20.7 19.3 17.1 18.5 17.5 27.2 19.2 18.1 5.9 20.0 18.5 24.6 61.0 22.2 11.6 30.9 27.6 39.1 25.8 28.5 20.2 0.0 55.4 9.0 31.5 80.3 68.6 2.5 14.6 24.3 29.2 19.9 16.4 5.1 78.0 71.1 24.9 25.5 20.0 33.0 35.4 25.4 43.8 93.0 11.8 4.4 22.3 42.7 44.5 50.3 7.8 20.8 53.1 12.4 1.9 79.3 22.6 9.2 4.5 4.5 54.8 48.4 25.6 51.7 30.9 66.9 95.2 19.6 9.8 46.0 18.4 33.2 25.8 14.1 25.7 27.4 69.4 12.1 45.5 26.0 27.0 BLVRA BLVR ENSG00000106605 "Biliverdin reductase A" P53004 7 43758680-43807342 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 259.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019709, HPA042865, HPA054322" Approved Supported Cytosol NA NA 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA019709: AB_2670239, HPA042865: AB_10797024, HPA054322: AB_2682450" "unprognostic (2.47e-2)" "unprognostic (8.38e-3)" "unprognostic (1.79e-2)" "unprognostic (2.16e-3)" "unprognostic (6.45e-3)" "unprognostic (5.01e-2)" "unprognostic (1.63e-2)" "prognostic favorable (8.65e-4)" "unprognostic (1.42e-1)" "unprognostic (1.75e-2)" "unprognostic (2.93e-1)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (5.63e-3)" "unprognostic (3.18e-1)" "unprognostic (2.13e-3)" "unprognostic (4.56e-2)" 53.2 28.0 31.4 39.7 33.4 65.6 49.9 32.0 40.1 44.3 31.4 61.4 12.5 38.5 129.9 67.5 40.9 33.4 52.7 32.3 34.7 41.3 14.6 62.7 58.6 34.1 33.6 46.6 23.5 54.9 26.2 28.9 34.2 38.4 19.8 25.4 36.5 46.0 59.7 33.4 27.7 54.1 33.1 82.0 35.3 13.1 34.0 43.0 31.3 69.3 52.6 43.5 40.4 32.0 48.6 92.2 26.2 110.5 55.0 72.7 1.3 32.3 99.3 54.0 65.4 22.2 28.3 0.3 60.6 51.5 190.7 62.1 82.1 81.7 46.2 227.3 56.8 104.1 86.6 138.1 139.5 11.8 37.5 49.9 135.7 57.2 37.8 108.5 92.7 51.1 70.2 55.7 41.4 52.5 37.0 6.3 35.9 11.0 104.7 80.4 45.6 261.4 121.1 26.6 34.0 104.4 65.9 65.1 55.2 46.2 146.7 77.7 57.0 49.3 53.9 21.8 56.0 74.7 63.2 0.2 80.8 46.9 78.4 51.1 291.9 169.2 39.1 374.9 36.7 26.9 75.7 64.9 135.4 17.0 39.7 31.0 26.5 22.4 368.4 20.1 82.2 208.5 31.4 33.4 32.0 40.1 32.3 34.7 34.1 33.6 34.2 33.1 34.0 32.0 22.0 60.9 85.0 7.5 10.7 29.1 64.2 102.4 34.1 18.0 29.6 36.1 59.4 17.2 75.7 35.0 2.1 9.7 9.3 0.3 56.7 52.6 0.7 31.6 20.2 27.3 0.0 74.7 8.4 35.1 8.1 39.7 8.2 41.4 111.5 17.2 24.3 1.9 259.1 8.4 11.5 0.4 59.0 136.5 53.7 1.6 37.0 80.4 46.2 2.8 147.3 36.6 13.4 7.5 4.3 25.2 1.2 29.0 16.6 87.9 7.1 110.5 69.6 13.0 46.0 23.0 50.6 3.0 14.2 52.9 34.4 5.2 23.4 4.9 0.6 48.7 BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916365 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 242.9;granulocytes: 129.2;Hofbauer cells: 140.4;Microglial cells: 351.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 50.1;HEL: 73.6;HMC-1: 80.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles" "HPA026436: AB_10600102, HPA026451: AB_10600228, HPA026501: AB_10601341" "unprognostic (7.96e-2)" "unprognostic (3.68e-1)" "prognostic favorable (1.74e-4)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (9.73e-3)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (9.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-2)" 6.0 4.2 8.5 13.5 8.2 11.9 7.4 7.3 7.2 6.5 3.8 9.5 5.6 4.4 5.4 7.4 6.0 7.4 8.0 7.2 18.6 4.9 6.7 7.7 16.5 12.1 11.2 3.1 3.5 4.3 0.6 9.2 13.5 3.3 11.9 6.5 3.5 3.5 2.2 9.9 6.9 6.6 10.9 12.2 4.7 10.2 9.8 10.9 7.7 4.5 16.3 7.1 1.4 16.5 11.4 3.2 6.0 7.5 12.0 11.1 4.8 10.8 14.4 10.3 13.7 6.4 6.4 13.2 5.6 50.1 9.9 2.9 6.7 8.5 19.4 3.5 2.3 73.6 5.0 3.5 13.2 15.9 80.6 15.9 11.0 16.4 15.6 7.3 14.4 10.0 19.8 36.5 12.1 2.4 9.5 7.4 2.9 8.8 2.1 13.5 10.3 3.7 13.3 5.2 8.4 5.2 14.2 7.8 10.4 7.9 2.7 10.0 14.7 10.6 4.2 18.4 11.9 7.7 3.2 4.8 9.9 21.4 7.7 0.1 0.5 0.3 0.0 0.2 0.0 0.6 0.0 0.0 0.4 0.6 0.1 0.0 0.9 0.1 0.8 0.3 0.0 0.1 8.5 8.2 7.3 7.2 7.2 18.6 12.1 11.2 13.5 10.9 9.8 16.5 10.7 28.9 16.2 242.9 31.5 25.0 4.3 5.4 10.2 10.9 27.4 15.2 6.5 2.8 7.7 7.3 4.2 5.0 6.1 24.6 0.0 7.5 15.9 18.6 12.7 17.6 6.7 105.4 53.2 8.8 14.2 13.7 6.6 25.0 129.2 32.1 22.1 19.7 140.4 10.1 59.0 48.2 6.1 65.9 68.2 11.1 8.1 65.4 28.4 351.3 34.6 37.0 1.0 49.3 59.1 14.6 43.0 6.8 7.6 6.3 19.9 18.0 12.3 8.4 6.6 22.3 11.7 26.1 11.2 17.1 31.4 3.4 7.6 5.4 24.0 3.2 BRI3 ENSG00000164713 "Brain protein I3" O95415 7 98252379-98310441 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 42.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042215 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA042215: AB_10794790" "unprognostic (1.51e-2)" "unprognostic (5.03e-2)" "unprognostic (7.08e-3)" "unprognostic (3.48e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.35e-4)" "unprognostic (2.04e-2)" "unprognostic (1.88e-2)" "unprognostic (3.93e-1)" "unprognostic (4.68e-1)" "unprognostic (1.66e-1)" "unprognostic (6.60e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-1)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (3.71e-1)" 132.7 159.3 42.2 37.0 45.0 94.8 102.2 42.8 46.2 88.3 50.0 94.0 67.6 80.1 31.7 63.6 72.1 45.3 150.6 36.4 42.0 122.6 179.4 167.3 32.9 46.4 44.2 73.9 127.4 24.1 98.5 69.1 44.3 84.6 35.8 10.8 93.5 26.4 237.0 82.1 81.2 33.6 41.6 122.4 133.1 53.2 56.6 14.1 78.8 65.1 18.3 99.3 69.4 46.0 130.5 20.6 36.6 47.3 231.8 104.0 86.6 105.1 122.4 86.6 114.5 17.1 60.0 13.6 220.3 191.8 275.6 45.5 46.9 66.7 59.9 46.5 53.4 8.7 15.0 29.9 228.2 10.0 43.3 85.7 95.3 74.2 135.2 119.8 107.6 15.9 26.6 84.2 164.4 9.1 32.1 32.9 44.1 87.8 55.3 30.8 20.2 43.7 83.2 9.3 30.6 62.3 27.7 114.4 279.2 63.2 12.2 64.0 108.4 175.1 103.4 228.1 82.6 91.5 128.3 35.9 199.5 44.4 91.8 2.5 15.0 24.2 0.9 25.3 1.3 0.9 0.9 1.0 7.0 1.1 1.5 1.3 42.8 0.2 24.0 10.3 3.0 3.1 42.2 45.0 42.8 46.2 36.4 42.0 46.4 44.2 44.3 41.6 56.6 46.0 354.9 83.3 120.3 18.3 52.8 146.3 278.2 24.1 47.3 90.6 191.1 277.6 121.9 204.5 37.4 134.3 33.3 122.9 118.4 193.5 569.4 62.1 680.8 176.9 149.2 223.9 78.5 49.0 13.8 119.5 431.4 161.6 122.3 192.0 22.8 140.8 238.1 258.0 695.0 129.5 17.8 161.9 26.4 482.9 329.4 132.1 100.3 503.0 167.2 20.6 167.5 291.4 28.8 15.1 26.6 82.4 234.2 121.5 37.4 416.5 261.5 670.8 35.8 84.2 111.7 166.2 145.6 61.6 58.5 59.0 171.5 169.4 48.7 131.3 154.6 473.3 C11orf45 "FLJ43646, MGC35558" ENSG00000174370 "Chromosome 11 open reading frame 45" Q8TAV5 11 128899565-128906035 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.7;Hofbauer cells: 8.7;Kupffer cells: 5.9;Late spermatids: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.2;U-937: 8.9" HPA039716 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA039716: AB_10672892" "unprognostic (8.32e-2)" "unprognostic (3.93e-2)" "unprognostic (5.99e-3)" "unprognostic (1.35e-3)" "unprognostic (1.01e-1)" "unprognostic (9.93e-2)" "unprognostic (4.50e-5)" "unprognostic (1.97e-2)" "unprognostic (4.78e-2)" "unprognostic (3.10e-1)" "unprognostic (2.80e-1)" "unprognostic (9.27e-2)" "unprognostic (2.55e-9)" "unprognostic (2.37e-1)" "unprognostic (2.60e-2)" "unprognostic (6.87e-2)" "unprognostic (7.22e-2)" 0.6 3.3 1.7 0.7 4.4 0.8 0.9 0.6 2.1 1.0 0.8 0.7 1.4 0.5 0.6 2.9 1.0 2.0 4.5 1.4 1.6 2.0 0.5 2.6 0.8 1.9 1.9 0.9 2.6 3.8 2.3 2.1 1.6 1.1 0.9 0.2 1.6 2.8 0.1 6.6 0.9 0.5 1.1 1.5 1.8 1.1 2.3 2.4 1.8 0.2 0.9 1.2 1.3 2.2 2.4 4.5 0.0 0.0 0.3 0.4 1.6 0.8 4.7 1.7 4.2 6.3 5.8 0.0 3.2 0.5 4.2 2.3 2.4 11.2 0.8 0.0 1.1 0.3 2.7 0.0 0.2 0.0 0.0 0.3 1.5 1.3 0.9 3.8 1.0 3.5 0.0 0.2 2.0 1.2 2.6 2.4 1.8 1.0 3.9 1.1 4.6 0.5 3.9 1.1 0.0 0.2 1.8 5.0 0.3 1.2 0.8 4.4 0.5 0.0 6.2 0.0 0.8 0.1 0.0 0.0 0.8 8.9 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.9 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.7 4.4 0.6 2.1 1.4 1.6 1.9 1.9 1.6 1.1 2.3 2.2 0.1 0.0 0.5 0.0 0.0 2.8 1.3 0.9 5.7 0.0 0.3 0.4 1.7 0.0 0.2 0.0 0.0 2.0 0.0 0.1 1.9 1.0 2.0 0.3 0.1 0.2 0.0 0.0 0.3 0.8 2.1 0.3 0.0 0.5 1.3 0.3 0.4 0.0 8.7 0.0 0.2 0.1 0.0 5.9 0.8 8.2 0.0 2.2 0.0 2.8 0.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 1.5 1.7 3.0 0.9 1.2 0.2 0.1 0.2 1.1 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 CALHM6 "C6orf187, dJ93H18.5, FAM26F, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5" ENSG00000188820 "Calcium homeostasis modulator family member 6" Q5R3K3 6 116461370-116463771 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 136.6" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 724.6;non-classical monocyte: 861.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 28.0;Karpas-707: 45.1;RPMI-8226: 159.8;U-937: 59.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.14e-2)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (7.15e-3)" "unprognostic (9.53e-3)" "unprognostic (4.10e-2)" "unprognostic (2.69e-1)" "unprognostic (1.68e-1)" "unprognostic (8.19e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (9.31e-10)" "unprognostic (1.69e-1)" "unprognostic (2.12e-2)" "unprognostic (3.85e-3)" "unprognostic (9.25e-3)" 7.4 7.3 4.9 60.2 5.2 41.4 10.0 4.5 6.6 4.3 5.0 10.4 12.2 2.4 3.6 4.1 4.1 7.2 4.3 4.7 5.2 4.1 24.7 10.8 73.0 8.1 4.7 4.5 1.8 1.7 4.8 12.5 5.3 5.4 7.0 1.1 5.7 3.0 1.6 1.9 20.9 11.8 5.6 136.6 7.9 8.2 5.3 14.0 2.4 2.6 23.1 11.4 3.0 5.4 6.4 0.0 0.6 0.4 0.5 2.0 11.7 0.2 1.3 2.0 1.3 0.0 1.0 0.2 3.5 1.5 0.0 0.0 0.3 0.2 4.2 0.7 0.4 28.0 0.0 0.0 2.8 0.1 0.1 2.2 0.0 0.2 0.2 0.5 0.7 0.0 0.0 45.1 5.5 0.0 2.7 4.8 3.6 0.0 0.0 2.4 0.0 159.8 2.2 0.3 2.7 0.1 14.9 0.1 11.7 1.6 0.2 7.3 0.1 0.0 0.2 0.1 0.9 11.4 0.2 0.0 0.3 59.7 3.9 22.0 205.7 50.1 16.6 724.6 16.6 231.8 23.0 15.5 193.8 308.9 28.9 15.2 115.8 27.4 861.9 86.5 2.7 175.6 4.9 5.2 4.5 6.6 4.7 5.2 8.1 4.7 5.3 5.6 5.3 5.4 0.6 0.0 1.7 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 0.0 0.2 0.3 0.8 0.0 0.0 0.0 10.0 9.0 0.7 0.0 0.1 0.0 1.4 0.0 0.0 138.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.2 1.2 1.8 0.0 0.0 CAMK1 "CaMKI, CaMKI-alpha" ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757347-9769992 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 58.3;Hofbauer cells: 76.2;Macrophages: 71.2;Sertoli cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 280.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 280.5" "Cell line enriched" "Detected in many" 4 "HMC-1: 403.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol NA NA 110000 "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB031904: AB_630964, HPA051409: AB_2681473" "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 52.4 99.7 50.1 17.2 48.9 5.1 37.2 39.9 61.0 27.0 31.8 33.6 9.2 31.8 13.7 8.0 37.0 11.1 20.5 61.2 46.3 24.9 36.4 23.9 11.1 37.8 41.7 41.2 8.4 14.4 21.6 6.7 38.8 31.1 10.6 5.9 9.8 19.7 7.1 7.9 16.5 26.0 36.8 16.7 21.7 29.8 46.9 4.3 19.5 7.8 15.0 28.4 18.3 46.1 0.5 16.4 12.6 0.0 64.7 24.3 32.6 38.4 21.1 43.1 40.4 24.1 3.0 1.1 9.0 26.0 6.2 2.7 0.0 5.0 27.0 0.4 95.4 53.5 32.1 34.1 35.9 4.5 403.3 25.3 4.1 60.6 6.7 35.4 36.8 0.9 7.2 1.2 16.3 10.3 0.3 38.8 9.0 0.4 25.7 0.3 0.4 1.1 25.9 2.8 4.2 16.7 6.6 0.7 4.0 5.3 4.1 67.2 19.6 19.8 24.4 28.0 48.7 0.4 0.3 1.0 41.5 14.7 3.0 17.8 21.3 280.5 0.3 42.2 0.1 0.1 0.4 0.2 14.1 0.2 0.3 0.1 1.0 3.6 43.0 0.4 2.0 4.7 50.1 48.9 39.9 61.0 61.2 46.3 37.8 41.7 38.8 36.8 46.9 46.1 58.3 0.0 3.1 17.9 2.8 5.0 19.2 3.4 5.7 9.9 5.2 4.6 0.1 12.8 2.1 11.0 2.1 0.4 3.0 2.6 9.8 14.4 1.8 1.8 14.9 22.8 6.0 4.8 25.6 4.0 1.2 23.3 5.6 3.1 30.5 16.7 30.4 23.5 76.2 0.0 14.5 2.3 0.0 46.4 40.2 7.2 36.1 71.2 5.4 8.4 36.7 39.4 3.1 6.6 2.7 5.5 2.9 45.1 0.2 17.5 3.6 47.4 1.3 7.7 59.2 12.2 42.7 1.5 3.7 1.5 3.8 0.8 7.1 6.6 7.6 11.0 CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 548.8;Hofbauer cells: 1107.4;Macrophages: 432.1;monocytes: 432.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1136.5;classical monocyte: 1139.3;eosinophil: 712.7;intermediate monocyte: 431.6;memory B-cell: 575.6;myeloid DC: 1363.2;naive B-cell: 516.8;NK-cell: 605.5;plasmacytoid DC: 959.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 563.6;HMC-1: 972.7;SK-MEL-30: 722.2;THP-1: 513.5;U-937: 569.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Enhanced Nucleoplasm Yes No 5400000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA018843: AB_2669948, HPA019080: AB_1845979, HPA019092: AB_1845980" "unprognostic (2.82e-2)" "unprognostic (1.37e-1)" "unprognostic (8.80e-2)" "unprognostic (1.28e-2)" "unprognostic (4.37e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-5)" "unprognostic (8.83e-2)" "unprognostic (3.22e-2)" "unprognostic (1.54e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-1)" "prognostic favorable (2.96e-4)" "unprognostic (1.45e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-3)" "unprognostic (7.89e-3)" 92.4 26.3 42.8 82.4 44.2 159.3 94.9 46.3 79.6 119.1 37.5 56.9 30.3 50.0 46.2 289.5 48.7 44.4 19.2 41.7 51.1 201.1 8.9 175.7 117.9 60.2 46.3 19.7 44.9 151.7 27.2 26.1 57.2 76.5 42.9 4.2 111.8 38.0 16.5 219.9 54.2 24.5 57.5 46.2 94.4 26.0 66.1 58.0 162.3 5.8 109.5 97.1 174.8 79.4 165.5 75.9 0.7 6.9 50.2 102.8 83.7 59.6 6.1 51.2 49.8 9.4 563.6 28.1 96.6 116.0 64.0 181.1 0.2 113.7 23.0 142.0 4.4 74.3 128.0 29.3 40.6 44.8 972.7 93.8 80.5 53.8 70.3 3.6 37.5 143.8 8.2 60.1 38.1 150.1 101.3 414.8 23.2 166.5 112.8 87.3 13.3 11.8 220.6 77.7 0.8 1.4 86.9 128.4 722.2 44.2 40.0 513.5 148.7 111.6 26.8 4.6 2.4 1.4 6.2 10.3 259.5 569.5 1.5 1136.5 1139.3 712.7 12.2 431.6 39.2 575.6 107.8 41.1 1363.2 516.8 30.5 13.9 162.9 605.5 131.3 959.7 122.1 977.9 42.8 44.2 46.3 79.6 41.7 51.1 60.2 46.3 57.2 57.5 66.1 79.4 6.6 19.2 24.5 3.3 84.7 121.2 167.5 265.0 60.9 0.8 86.8 70.4 1.3 51.5 119.6 316.3 0.0 34.3 91.5 211.0 211.3 113.8 4.1 33.0 10.3 16.2 28.8 16.0 0.2 91.5 324.0 34.7 124.9 63.9 548.8 1.2 3.6 1.1 1107.4 1.7 0.2 55.9 50.8 141.6 337.2 15.2 46.9 432.1 147.7 1.0 432.4 43.6 11.3 0.5 0.1 405.8 205.4 22.6 17.2 106.0 74.1 168.5 48.8 1.7 13.1 2.0 54.0 9.6 33.1 167.4 169.5 35.7 101.9 0.9 83.9 253.1 CCDC22 "CXorf37, JM1" ENSG00000101997 "Coiled-coil domain containing 22" O60826 X 49235470-49250520 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport, Ubl conjugation pathway" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000229, HPA000888, HPA075980" Uncertain Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Vesicles" "HPA000229: , HPA000888: AB_1078420, HPA075980: " "unprognostic (1.24e-2)" "unprognostic (1.96e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-1)" "unprognostic (1.36e-1)" "unprognostic (2.80e-2)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-2)" "unprognostic (2.62e-2)" "unprognostic (1.70e-1)" "unprognostic (4.57e-3)" "unprognostic (3.61e-2)" "unprognostic (4.99e-2)" "unprognostic (6.99e-2)" "unprognostic (2.57e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-3)" 10.3 12.3 9.4 10.1 10.0 18.6 10.3 9.9 10.8 11.7 8.8 12.1 10.4 12.2 5.3 14.2 11.3 6.4 12.8 9.4 9.2 12.3 12.9 10.7 15.0 10.8 9.4 11.2 14.2 8.7 11.2 6.9 10.1 13.5 5.2 4.7 12.3 8.7 17.2 13.8 13.4 6.0 9.6 20.5 12.9 3.8 10.0 13.6 11.0 7.7 8.5 11.9 11.1 10.8 18.8 16.0 9.6 33.5 8.8 8.9 20.4 10.9 7.9 12.0 13.6 16.3 16.0 6.9 15.9 9.7 14.3 15.0 10.6 18.0 4.9 18.1 23.6 7.3 15.6 15.5 14.7 20.8 12.4 8.2 15.2 15.9 8.6 6.1 11.9 13.7 14.7 11.8 8.6 58.3 15.3 24.4 11.2 9.5 23.2 22.0 15.6 30.1 9.4 9.4 11.4 8.8 16.7 19.4 15.0 9.8 30.2 20.2 13.3 15.4 16.5 19.2 11.6 21.2 12.6 12.5 16.8 38.5 12.3 8.6 37.0 23.8 18.3 30.9 20.1 18.9 18.8 21.3 38.2 16.8 16.7 19.6 2.8 10.8 27.1 15.1 21.8 28.0 9.4 10.0 9.9 10.8 9.4 9.2 10.8 9.4 10.1 9.6 10.0 10.8 8.6 0.0 4.4 3.3 15.0 5.6 9.6 13.0 6.2 11.6 7.4 6.1 2.4 15.7 12.0 11.0 6.2 15.2 11.2 12.5 15.6 13.9 0.3 5.8 4.6 7.8 6.7 8.6 3.7 7.3 14.8 7.6 7.1 6.9 11.4 8.6 11.0 7.2 32.0 1.7 2.9 18.2 8.2 14.4 11.9 0.4 8.1 13.8 7.2 1.9 18.0 9.9 9.2 1.0 4.2 8.6 7.6 7.5 10.2 6.2 15.6 12.1 5.6 8.0 6.6 9.1 9.5 0.1 0.9 8.0 6.7 20.2 13.3 11.0 15.7 8.3 CCL18 "AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18" ENSG00000275385 "C-C motif chemokine ligand 18" P55774 17 36064272-36072032 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lung: 48.7" "Group enriched" "Detected in some" 5 "Hofbauer cells: 189.1;Langerhans cells: 104.3;Macrophages: 153.1" "Cancer enhanced" "Detected in all" "lung cancer: 76.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 55500000 6400000 "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (8.91e-2)" "unprognostic (2.96e-2)" "unprognostic (5.71e-2)" "unprognostic (9.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" "unprognostic (2.50e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.68e-1)" "unprognostic (3.63e-1)" "unprognostic (4.87e-2)" 9.7 0.3 0.0 2.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 2.0 3.9 0.1 0.0 0.9 0.4 0.0 1.6 0.0 0.0 0.2 0.3 48.7 7.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 2.5 0.0 0.0 0.9 9.2 1.5 0.0 4.0 0.2 0.5 0.1 6.1 1.1 0.0 5.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 25.4 0.0 1.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 0.0 0.0 0.5 4.2 0.0 0.0 0.0 24.5 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.1 0.0 0.4 0.7 189.1 0.0 0.0 0.0 0.0 4.2 104.3 5.3 0.0 153.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.4 0.9 0.0 0.1 0.1 3.4 1.6 2.9 0.0 0.0 0.0 CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.7;lung: 35.8;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in many" "dendritic cells: 441.4;Hofbauer cells: 2084.4;Kupffer cells: 723.2;Langerhans cells: 710.0;Macrophages: 1534.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.6" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.6" "Cell line enhanced" "Detected in some" "Karpas-707: 443.8;U-266/70: 602.5;U-266/84: 2043.3" "Secreted to blood" NA NA 138000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (7.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-1)" "unprognostic (8.90e-2)" "unprognostic (7.92e-3)" "unprognostic (2.00e-1)" "unprognostic (7.20e-2)" "unprognostic (2.05e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-2)" 17.6 16.0 0.0 8.1 0.7 76.7 5.6 0.0 1.4 1.5 0.0 2.5 0.0 1.1 0.0 0.5 2.9 10.3 3.7 0.0 0.0 4.6 12.9 35.8 1.8 0.7 0.0 1.2 1.3 0.0 1.7 2.4 0.0 2.2 0.0 0.0 5.6 0.0 0.8 0.8 3.1 0.0 0.0 49.4 3.0 0.7 0.5 0.0 2.0 0.0 0.0 3.0 1.4 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.8 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 55.6 0.0 0.0 1.3 602.5 2043.3 0.0 0.0 0.0 0.0 0.0 2.1 10.8 23.6 1.3 0.0 5.1 0.0 6.1 0.4 10.4 0.1 6.8 10.5 3.5 1.3 0.0 0.0 11.6 0.0 0.7 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.5 1.4 33.0 0.0 28.6 0.0 45.3 27.9 2.0 0.2 1.2 1.8 23.1 50.0 2.2 4.3 4.4 0.0 0.0 19.0 441.4 0.7 0.0 0.6 1.5 1.6 2.5 115.9 0.0 61.9 0.0 0.2 22.6 14.5 2.0 2.8 23.5 0.1 27.1 9.1 2084.4 0.0 0.0 0.5 0.0 723.2 710.0 1.9 1.8 1534.2 94.3 2.8 23.5 2.1 106.1 0.0 0.0 0.4 0.0 0.0 344.8 1.2 0.0 0.9 2.2 3.7 6.6 2.3 9.2 0.5 0.6 0.6 28.8 54.3 248.0 0.1 0.2 1.3 CCL3L3 "CCL3L1, D17S1718, G0S19-2, LD78BETA, MGC12815, SCYA3L, SCYA3L1" ENSG00000276085 "C-C motif chemokine ligand 3 like 3" P16619 17 36194869-36196758 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.0;lung: 5.0;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 6 "Hofbauer cells: 335.4;Kupffer cells: 227.5;Macrophages: 321.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "eosinophil: 4.2;neutrophil: 1.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Group enriched" "Detected in some" 41 "U-266/70: 49.4;U-266/84: 107.3" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "unprognostic (5.37e-2)" "unprognostic (1.46e-1)" "unprognostic (9.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.36e-2)" "unprognostic (3.69e-1)" "unprognostic (5.75e-2)" "unprognostic (5.55e-2)" "unprognostic (2.40e-2)" "unprognostic (3.66e-1)" "unprognostic (9.08e-2)" "unprognostic (2.09e-1)" "unprognostic (3.21e-1)" "unprognostic (1.90e-2)" "unprognostic (8.58e-2)" 1.6 0.9 0.0 0.3 0.0 11.0 0.7 0.0 0.3 0.1 0.0 0.5 0.1 0.2 0.2 0.1 0.7 0.9 0.4 0.0 0.0 1.1 1.2 5.0 0.5 0.0 0.0 0.2 0.2 0.0 0.3 0.3 0.0 0.5 0.0 0.0 1.3 0.1 0.1 0.1 0.8 0.1 0.0 4.0 0.5 0.5 0.0 0.1 0.3 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.1 49.4 107.3 1.2 0.0 0.0 0.0 0.1 0.0 4.2 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.3 0.5 0.0 2.2 0.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.9 0.0 0.7 0.0 0.0 0.1 0.0 0.0 48.8 0.0 16.0 0.0 0.0 4.4 1.3 0.5 0.0 0.0 0.0 8.6 1.0 335.4 0.0 0.0 0.5 0.0 227.5 2.9 0.9 0.6 321.7 1.8 1.9 1.6 0.7 10.3 0.0 0.0 0.0 1.2 0.0 0.8 0.7 0.0 0.0 0.0 2.3 0.0 0.4 0.3 0.4 3.8 0.7 0.1 13.1 31.4 0.0 0.0 0.4 CCL7 "FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7" ENSG00000108688 "C-C motif chemokine ligand 7" P80098 17 34270221-34272242 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 25.9" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 56.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.5;BJ hTERT+ SV40 Large T+: 2.3;BJ hTERT+ SV40 Large T+ RasG12V: 2.8;HSkMC: 3.3" "Not detected" "Not detected" "Secreted to blood" NA NA 29700 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (7.66e-2)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (4.65e-2)" "unprognostic (2.54e-2)" "unprognostic (9.54e-2)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (2.63e-2)" "unprognostic (2.27e-3)" "unprognostic (7.04e-2)" "unprognostic (1.99e-8)" "unprognostic (2.83e-1)" "unprognostic (8.74e-2)" "unprognostic (3.74e-1)" "unprognostic (1.79e-2)" 0.8 0.2 0.0 2.5 0.0 25.9 0.1 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.7 0.3 0.0 0.0 0.5 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 2.3 0.3 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 11.5 2.3 2.8 0.0 0.0 0.0 0.4 0.8 0.0 1.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.3 0.0 0.9 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD200R1 "CD200R, HCRTR2, MOX2R, OX2R" ENSG00000163606 "CD200 receptor 1" Q8TD46 3 112921205-112975103 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;granulocytes: 15.2;Hepatic stellate cells: 14.6;Hofbauer cells: 31.8;Langerhans cells: 19.9;T-cells: 12.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 234.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 234.9" "Cell line enriched" "Detected in some" 8 "HEL: 25.5" HPA068512 Supported "Plasma membrane" "Intracellular and membrane" NA NA 2000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA068512: AB_2732784" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-3)" "unprognostic (8.30e-2)" "unprognostic (1.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.77e-1)" "unprognostic (7.84e-3)" "unprognostic (1.25e-1)" "unprognostic (5.12e-3)" 1.7 1.2 0.3 3.0 0.4 1.7 1.4 0.2 0.6 0.7 0.7 1.5 1.6 0.7 0.3 3.8 0.5 1.9 0.6 0.4 0.3 0.5 2.4 1.9 4.4 0.3 0.2 0.3 0.5 0.5 0.2 5.3 0.3 0.6 2.3 0.1 0.6 0.7 0.1 2.6 2.0 1.1 0.2 7.9 1.5 0.7 0.2 3.4 0.5 0.9 4.6 1.9 0.5 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.3 25.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.2 0.0 234.9 2.9 53.6 4.0 1.3 7.0 9.9 13.8 7.9 22.9 5.6 13.4 6.1 0.8 2.5 0.4 0.5 4.3 5.2 0.3 0.4 0.2 0.6 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.0 1.1 1.6 4.4 1.9 0.1 0.0 14.8 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.1 1.0 0.1 0.5 0.0 4.0 5.7 0.0 0.2 0.9 0.0 0.1 15.2 0.0 14.6 0.1 31.8 0.0 2.2 0.0 0.0 6.7 19.9 0.0 0.0 9.1 5.4 5.6 5.2 0.0 0.0 1.0 0.7 0.1 0.0 0.0 2.7 0.1 0.0 0.1 1.2 0.0 0.0 0.3 0.4 0.8 0.3 5.8 0.9 0.7 12.4 0.0 0.0 0.2 CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.2;placenta: 22.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 15.6;Langerhans cells: 14.7;Macrophages: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 4 "dendritic cells: 1.2;monocytes: 1.4" "Cell line enriched" "Detected in single" 14 "THP-1: 3.3" "CAB032436, CAB033831" Supported "Intracellular and membrane" NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" 34.2 3.9 0.3 8.6 0.6 0.4 4.4 1.3 3.0 4.0 5.7 10.5 14.3 1.4 1.0 4.8 2.5 8.6 4.5 0.3 0.7 2.1 3.3 4.9 18.1 1.0 0.6 1.0 1.0 0.8 0.7 22.8 0.8 0.8 13.9 0.1 2.1 1.9 0.9 1.4 19.3 10.6 0.9 2.4 4.1 2.1 0.6 5.4 1.4 1.5 2.3 20.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.4 0.3 0.6 1.3 3.0 0.3 0.7 1.0 0.6 0.8 0.9 0.6 0.8 0.3 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 15.6 14.7 0.3 0.0 12.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.1 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD4 ENSG00000010610 "CD4 molecule" P01730 12 6786858-6820799 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.9;lymphoid tissue: 219.3;parathyroid gland: 173.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 278.8;Hofbauer cells: 139.3;Kupffer cells: 247.1;Langerhans cells: 80.1;Macrophages: 109.0;monocytes: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 18 "classical monocyte: 247.3;intermediate monocyte: 241.4;memory CD4 T-cell: 153.4;myeloid DC: 166.3;naive CD4 T-cell: 128.1;non-classical monocyte: 204.2;plasmacytoid DC: 263.8;T-reg: 154.5" "Group enriched" "Detected in many" 20 "dendritic cells: 263.8;monocytes: 247.3;T-cells: 154.5" "Group enriched" "Detected in some" 6 "HEL: 103.2;HL-60: 42.1;NB-4: 60.0;THP-1: 116.2;U-937: 109.7" "Region enriched" "Detected in many" 14 "basal ganglia: 46.2" "Low region specificity" "Detected in many" "CAB000011, HPA004252, HPA004472, CAB068180" Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB000011: AB_442062, CAB068180: AB_2665653, HPA004252: AB_1078466, HPA004472: AB_1078465" "unprognostic (1.39e-2)" "unprognostic (1.12e-2)" "unprognostic (2.75e-2)" "prognostic favorable (2.16e-4)" "unprognostic (7.76e-2)" "unprognostic (4.82e-3)" "unprognostic (3.70e-2)" "unprognostic (2.74e-2)" "unprognostic (7.04e-2)" "unprognostic (2.40e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.06e-1)" "unprognostic (4.65e-3)" "unprognostic (9.08e-3)" "unprognostic (2.95e-1)" 45.5 16.2 15.0 82.1 15.4 26.5 14.7 15.5 17.4 20.4 15.8 26.0 18.7 7.9 7.0 15.1 21.3 35.3 10.0 15.1 16.7 10.1 152.9 72.1 119.0 22.9 20.2 8.6 7.6 173.8 6.1 47.4 21.0 7.3 31.0 10.5 8.5 10.3 2.9 12.6 27.4 26.5 19.6 164.4 21.0 7.5 19.6 219.3 8.8 5.7 75.7 41.0 5.8 25.7 0.0 0.0 3.6 0.1 0.1 0.2 0.3 0.1 2.4 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 103.2 0.0 0.6 10.5 42.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 15.4 60.0 1.0 0.0 0.0 0.0 0.2 12.8 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.7 0.1 116.2 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.1 109.7 0.0 0.8 247.3 1.9 2.0 241.4 6.3 0.5 153.4 0.8 166.3 0.5 128.1 0.7 11.1 2.0 204.2 263.8 154.5 240.6 15.0 15.4 15.5 17.4 15.1 16.7 22.9 20.2 21.0 19.6 19.6 25.7 4.5 0.0 5.2 1.6 5.2 3.4 0.3 0.4 0.0 1.5 2.9 5.8 2.1 8.6 2.1 3.7 0.0 0.9 61.9 0.0 5.9 0.0 0.1 3.5 8.7 9.6 0.0 7.8 0.9 0.4 1.2 3.7 0.0 0.4 7.6 0.4 278.8 34.3 139.3 5.0 0.7 0.0 0.0 247.1 80.1 0.5 16.8 109.0 5.4 29.0 104.5 22.0 6.2 0.5 0.2 0.0 0.0 15.1 2.5 0.2 0.0 3.3 20.3 0.2 13.1 0.7 13.5 0.0 0.2 0.4 2.3 1.2 34.0 0.0 0.0 0.4 CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 310.0;dendritic cells: 375.0;Hofbauer cells: 365.7;Kupffer cells: 324.3;Macrophages: 294.8;NK-cells: 383.1;T-cells: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 473.5;HDLM-2: 214.8;HMC-1: 298.4;Karpas-707: 188.1;U-266/70: 251.2;U-698: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" 63.4 30.8 10.1 284.4 11.1 126.6 27.0 12.6 16.3 20.8 12.3 41.5 37.9 17.3 10.5 20.0 22.8 58.5 12.2 9.7 13.4 15.1 46.8 114.9 397.9 18.9 16.0 9.2 11.9 6.6 6.2 58.5 18.9 12.8 54.8 2.0 19.3 12.8 4.5 6.7 103.4 55.8 18.3 269.4 44.3 5.7 17.5 144.9 11.3 10.6 448.3 85.1 9.0 31.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 473.5 0.2 0.0 0.2 0.5 0.0 0.0 0.0 214.8 0.0 26.4 0.1 0.0 0.0 60.4 298.4 0.0 0.0 0.0 0.0 0.0 0.0 139.2 11.2 188.1 0.0 0.0 103.1 71.1 0.4 0.0 0.0 98.0 0.7 104.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 1.5 0.0 88.4 17.2 0.2 0.4 0.1 0.5 251.2 123.2 149.2 1.5 68.7 3.4 1483.0 779.5 479.0 732.4 808.6 658.1 794.0 527.8 649.2 631.9 745.1 377.9 552.5 1144.2 526.6 882.9 517.5 740.3 1621.0 10.1 11.1 12.6 16.3 9.7 13.4 18.9 16.0 18.9 18.3 17.5 31.9 4.2 16.0 24.4 0.7 310.0 7.0 0.6 0.0 0.6 0.0 2.3 5.1 1.0 5.7 8.6 1.8 0.0 2.1 375.0 0.2 0.0 0.5 0.4 0.4 0.5 13.0 0.0 42.9 5.8 0.2 5.4 6.7 7.1 0.6 162.2 0.0 16.4 6.7 365.7 0.0 1.4 0.3 0.0 324.3 161.5 1.9 2.1 294.8 39.2 69.3 156.3 0.1 383.1 1.0 0.6 0.3 0.1 0.4 134.0 0.3 0.0 1.6 4.4 0.6 6.6 1.9 1.8 0.1 0.6 1.1 5.5 4.1 297.0 0.0 0.2 0.3 CD5L "API6, Spalpha" ENSG00000073754 "CD5 molecule like" O43866 1 157830911-157898256 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 572.9" "Group enriched" "Detected in some" 36 "Hofbauer cells: 279.0;Kupffer cells: 567.0" "Cancer enriched" "Detected in some" 5 "liver cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA065686, HPA068384" Enhanced "Secreted to blood" NA NA 4030000000 4300000000 "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA065686: AB_2685532, HPA068384: AB_2685979" "unprognostic (2.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.73e-2)" "unprognostic (4.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.56e-1)" "unprognostic (5.95e-3)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" "unprognostic (3.63e-1)" 1.4 0.0 0.0 1.5 0.0 17.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 104.7 1.6 9.2 0.2 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 572.9 0.5 0.1 0.1 6.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 6.1 6.1 279.0 0.0 0.0 0.0 0.0 567.0 0.0 1.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.3 0.3 0.0 0.0 0.0 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.2" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Hofbauer cells: 91.1;Kupffer cells: 177.0;Macrophages: 90.6;monocytes: 76.4;T-cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.8;HEL: 45.3;HL-60: 13.1;HMC-1: 49.7;MOLT-4: 12.9;U-698: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" 3.3 2.4 1.9 19.4 2.1 7.9 2.7 2.3 2.4 2.8 1.9 3.2 2.4 1.4 0.9 2.2 1.1 6.2 1.4 1.7 1.9 0.8 5.2 7.8 24.2 5.2 3.1 1.5 2.0 0.9 0.4 7.1 4.5 1.1 4.5 0.2 1.4 3.4 0.4 1.3 4.6 4.0 3.8 15.2 3.6 1.9 5.2 9.9 1.1 0.7 13.2 4.7 0.8 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 45.3 0.1 0.0 0.0 13.1 49.7 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.9 0.1 0.0 0.0 12.9 9.7 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.8 0.0 2.9 0.0 32.7 9.6 15.0 8.2 8.0 6.5 6.3 7.0 10.1 7.1 6.0 4.0 7.4 1.2 1.4 3.2 4.1 10.5 8.8 1.9 2.1 2.3 2.4 1.7 1.9 5.2 3.1 4.5 3.8 5.2 7.2 1.3 0.0 6.4 0.0 27.4 2.4 0.7 0.0 0.6 0.2 0.6 1.5 1.2 2.8 1.3 0.0 0.0 0.5 20.5 0.2 0.0 0.1 0.9 0.5 0.2 4.2 0.0 21.5 0.1 0.2 0.5 1.2 2.6 0.2 187.1 0.1 3.3 1.1 91.1 0.0 0.2 0.1 0.0 177.0 42.2 1.5 0.6 90.6 5.4 34.7 76.4 0.0 4.1 0.0 0.1 0.0 0.0 0.0 10.8 0.9 0.3 0.3 0.7 0.2 0.0 1.6 1.5 0.1 0.4 0.5 2.4 1.0 46.8 2.9 0.2 0.6 CEBPE CRP1 ENSG00000092067 "CCAAT enhancer binding protein epsilon" Q15744 14 23117306-23119255 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 51.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 6.6;Kupffer cells: 1.4;Macrophages: 2.3;monocytes: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 218 "eosinophil: 750.4" "Lineage enriched" "Detected in many" 250 "granulocytes: 750.4" "Group enriched" "Detected in some" 4 "HL-60: 233.8;NB-4: 122.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002928, CAB005113" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Plasma membrane, Cytosol" "CAB005113: AB_631240, HPA002928: AB_1078494" "unprognostic (1.33e-2)" "unprognostic (4.76e-2)" "unprognostic (4.19e-2)" "unprognostic (2.04e-1)" "unprognostic (5.01e-2)" "unprognostic (1.66e-3)" "unprognostic (2.84e-1)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (5.69e-2)" "unprognostic (9.03e-2)" "unprognostic (2.22e-1)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.57e-2)" "unprognostic (8.19e-2)" 0.1 0.0 0.1 1.6 0.1 51.8 0.0 0.0 0.2 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.5 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 3.2 0.3 0.1 3.4 0.8 0.0 0.3 0.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 233.8 39.6 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.9 122.5 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 26.3 0.0 0.5 3.0 750.4 0.0 0.6 0.1 0.5 1.0 0.4 1.5 0.5 1.8 1.5 3.4 0.0 0.3 1.5 0.0 1.8 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.0 1.4 0.6 0.1 0.0 2.3 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.6 0.1 0.0 0.0 CHCHD6 "CHCM1, MGC13016, Mic25, MICOS25, PPP1R23" ENSG00000159685 "Coiled-coil-helix-coiled-coil-helix domain containing 6" Q9BRQ6 3 126704240-126960420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Late spermatids: 106.6;Melanocytes: 172.5;Spermatocytes: 119.7" "Cancer enriched" "Detected in all" 4 "melanoma: 34.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047673, HPA051975" Approved Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA047673: AB_10961761, HPA051975: AB_2681679" "unprognostic (3.94e-2)" "prognostic favorable (7.46e-4)" "unprognostic (6.20e-2)" "unprognostic (1.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (6.83e-3)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" "unprognostic (1.31e-1)" "unprognostic (6.79e-2)" "unprognostic (2.08e-1)" "prognostic favorable (6.76e-4)" "unprognostic (6.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.11e-3)" 9.4 12.8 22.2 3.8 24.7 4.2 10.8 17.7 34.3 13.1 16.4 11.6 3.9 11.5 5.0 10.9 13.7 5.0 11.9 35.0 22.7 14.4 7.4 10.7 3.9 19.0 21.6 17.7 14.8 15.6 16.5 4.1 21.0 10.5 3.0 8.3 14.1 7.8 4.7 16.3 6.2 5.4 18.4 6.9 11.7 53.0 21.4 4.9 13.0 3.2 2.9 11.1 11.5 22.1 37.1 21.1 18.4 44.7 6.4 9.8 10.5 14.1 9.5 16.0 15.5 29.3 15.8 16.3 31.8 8.5 17.5 21.3 13.9 38.3 7.9 4.5 37.7 13.5 15.8 29.0 19.0 29.2 8.5 9.9 22.9 7.8 16.3 13.1 10.6 28.4 12.2 9.4 14.2 27.7 43.2 29.1 22.3 20.9 23.7 22.8 28.0 38.9 14.3 15.8 33.6 21.0 14.5 24.3 45.4 9.0 14.2 10.8 9.7 17.9 22.2 24.5 14.6 12.0 5.9 20.4 20.1 9.6 17.0 0.0 2.4 2.1 6.8 4.1 8.8 8.4 9.9 8.4 6.8 11.6 9.4 11.2 0.0 7.7 3.7 4.8 10.0 4.6 22.2 24.7 17.7 34.3 35.0 22.7 19.0 21.6 21.0 18.4 21.4 22.1 8.9 19.2 12.5 20.5 7.1 29.6 21.7 35.5 9.6 15.4 20.0 31.5 18.5 8.6 24.0 14.7 18.8 40.8 3.4 6.4 58.7 22.7 99.0 18.6 8.8 7.3 7.7 8.2 48.1 24.2 12.1 14.8 9.7 5.8 14.0 45.6 6.8 7.2 178.2 20.2 45.1 10.8 28.5 10.1 15.6 106.6 15.8 33.0 172.5 12.2 2.7 20.2 2.1 22.6 22.0 18.9 9.0 22.2 7.1 29.6 2.6 27.9 56.1 16.1 0.0 10.9 17.9 119.7 51.4 16.0 30.1 15.5 8.2 14.1 13.3 21.1 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.8;lung: 36.4;lymphoid tissue: 21.7" "Cell type enriched" "Detected in some" 10 "Hofbauer cells: 40.6" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Region enriched" "Detected in some" 6 "cerebral cortex: 12.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010575, HPA074844" Enhanced "Secreted to blood" NA NA 26400000 57000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Macrophages - Innate immune response" "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favorable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" 13.6 0.3 0.2 0.4 0.2 49.8 8.3 0.0 12.4 8.1 0.0 1.2 0.0 3.6 0.1 0.0 0.1 0.4 0.2 0.2 0.0 0.1 0.7 36.4 21.7 0.4 0.2 0.5 2.1 0.0 0.0 0.7 1.3 1.0 1.0 0.0 0.4 0.0 0.2 0.4 0.8 0.0 0.4 5.7 0.5 0.0 0.3 3.4 1.3 0.0 1.1 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.2 0.2 0.0 12.4 0.2 0.0 0.4 0.2 1.3 0.4 0.3 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 345.1;Spermatocytes: 300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1384.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA062779 Approved Vesicles "Secreted to blood" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062779: AB_2684867" "unprognostic (1.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (3.06e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.79e-2)" "unprognostic (8.05e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.06e-9)" "unprognostic (2.36e-1)" "unprognostic (2.65e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.07e-1)" 36.5 31.1 26.3 54.8 26.2 68.2 36.0 27.4 29.8 27.7 25.9 42.1 31.8 23.8 27.4 19.2 31.1 40.3 16.5 25.7 28.8 21.0 29.6 36.2 61.5 28.1 27.6 25.6 17.9 58.0 19.7 29.7 28.9 15.5 42.5 9.7 19.7 18.4 14.8 16.9 38.7 33.5 27.9 67.0 25.6 56.8 26.4 90.0 23.7 20.1 51.2 46.1 20.0 29.6 194.6 169.2 34.7 101.5 92.7 76.1 25.5 95.2 72.4 101.7 150.9 158.8 231.4 75.8 116.6 81.8 106.4 102.5 70.5 57.2 142.1 94.2 35.3 55.5 145.0 197.3 56.0 175.7 144.1 52.0 45.3 126.9 44.9 122.1 122.8 229.4 90.8 212.8 129.2 64.8 169.9 172.1 11.5 114.0 273.1 287.5 184.2 215.6 343.2 106.3 48.8 58.8 290.5 19.3 93.0 23.3 55.5 116.5 76.6 146.5 131.8 51.0 113.5 100.3 224.0 393.0 123.5 151.5 121.1 807.1 380.9 773.3 187.6 203.9 238.9 100.6 174.8 186.6 317.6 97.7 92.7 126.4 1384.5 187.6 199.2 161.6 236.0 401.2 26.3 26.2 27.4 29.8 25.7 28.8 28.1 27.6 28.9 27.9 26.4 29.6 65.7 19.2 49.0 0.0 68.7 27.3 24.7 84.2 12.0 8.4 80.8 94.0 1.8 87.2 50.8 57.0 0.0 54.8 109.7 57.1 17.6 141.4 67.7 34.8 21.5 52.4 33.0 63.5 0.0 130.0 117.7 38.6 21.4 17.5 345.1 17.7 67.5 38.4 247.4 1.7 0.0 73.6 61.1 138.2 238.4 31.4 49.4 244.2 40.9 0.0 157.8 28.1 188.4 0.0 0.0 224.2 51.3 30.1 94.6 10.0 95.9 83.4 79.3 9.0 32.9 24.5 38.1 300.0 77.1 30.8 23.0 17.4 192.6 23.9 79.0 25.8 CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 18.0;Langerhans cells: 67.5;Macrophages: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Group enriched" "Detected in some" 23 "HL-60: 40.9;U-937: 157.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" 1.1 1.8 1.1 7.3 1.2 41.3 0.6 1.3 2.6 0.7 2.1 0.2 0.1 0.3 0.0 1.2 0.5 1.8 0.5 1.0 3.3 0.5 1.8 4.0 0.1 2.2 3.3 0.3 1.3 1.2 0.5 0.9 2.2 0.4 0.3 1.0 1.2 0.5 0.0 2.6 0.0 1.3 1.6 1.1 0.2 0.5 4.9 0.6 0.7 0.0 0.1 2.3 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 9.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.8 1.1 1.2 1.3 2.6 1.0 3.3 2.2 3.3 2.2 1.6 4.9 2.4 0.1 0.0 4.8 0.7 0.6 1.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 1.5 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 2.5 0.0 0.0 0.0 18.0 0.0 0.2 0.0 0.0 4.7 67.5 0.7 0.0 58.1 1.8 7.5 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.9 0.4 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.3 0.4 0.0 0.0 0.0 CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in some" "dendritic cells: 17.3;Hofbauer cells: 32.4;Kupffer cells: 69.6;Macrophages: 27.1;Microglial cells: 39.4;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.5;plasmacytoid DC: 18.1" "Group enriched" "Detected in many" 22 "dendritic cells: 18.1;monocytes: 14.5;T-cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 11.9;ASC TERT1: 45.3;BJ hTERT+: 34.9;hTERT-RPE1: 13.6;LHCN-M2: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" 10.4 5.9 3.3 11.7 3.0 0.9 4.9 2.5 3.2 4.7 4.2 7.5 4.5 8.3 1.6 3.1 4.4 5.5 6.4 2.6 4.9 3.3 6.9 12.8 17.6 5.9 4.7 1.9 3.2 1.7 3.4 22.2 5.3 3.8 8.9 0.3 4.7 4.5 2.4 4.2 5.1 14.7 4.0 34.3 2.8 2.6 5.9 4.2 8.7 5.1 8.1 8.1 2.5 7.5 0.0 0.0 0.1 0.0 11.9 45.3 0.2 0.0 34.9 0.1 0.0 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.2 13.6 0.7 0.0 0.0 0.0 10.6 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.9 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 4.1 0.0 7.0 14.5 0.0 0.0 1.1 5.1 1.1 0.0 0.4 3.5 0.3 0.6 2.8 18.1 0.3 5.1 3.3 3.0 2.5 3.2 2.6 4.9 5.9 4.7 5.3 4.0 5.9 7.5 1.9 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.1 0.3 2.2 1.5 0.6 0.0 0.0 0.4 17.3 0.0 0.0 0.0 0.1 0.0 0.7 5.8 0.0 2.7 0.5 0.0 0.5 7.8 0.0 0.0 0.0 0.0 11.4 0.6 32.4 0.0 0.4 0.0 0.0 69.6 2.5 0.3 0.3 27.1 3.6 39.4 7.6 0.0 30.9 1.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.7 0.1 6.6 4.1 5.1 0.0 0.0 0.1 0.6 0.5 2.2 0.5 0.0 0.0 COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555649-17583162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 76.2;Hofbauer cells: 91.0;Kupffer cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047821 Approved Approved Vesicles "Intracellular and membrane" No No 9700 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA047821: AB_2680168" "unprognostic (2.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.65e-5)" "unprognostic (2.92e-3)" "unprognostic (2.92e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.43e-2)" "unprognostic (1.09e-1)" "unprognostic (8.87e-2)" "prognostic unfavorable (3.83e-4)" 38.6 14.3 5.9 38.1 6.9 32.9 27.5 7.9 8.4 31.1 10.6 27.7 16.2 28.4 4.4 17.9 26.5 19.0 22.4 7.1 9.1 12.7 16.3 34.9 29.7 12.1 9.3 23.5 15.8 9.0 10.1 40.9 12.3 15.5 15.2 3.2 15.9 16.3 15.1 23.9 24.7 35.4 7.6 39.5 18.2 11.9 18.9 9.9 14.7 7.5 15.8 28.1 22.8 12.6 103.1 118.0 56.7 79.8 222.3 136.3 90.9 95.9 55.1 121.8 125.9 90.4 159.6 53.0 164.7 166.9 104.2 91.5 58.4 110.6 73.4 29.5 94.9 51.2 147.4 87.9 121.6 123.0 147.8 115.2 97.6 136.7 56.7 49.7 138.8 33.3 105.5 25.8 45.1 45.6 61.9 81.1 43.0 75.8 115.3 65.2 73.8 80.9 26.4 67.2 41.2 29.9 102.8 80.6 97.0 36.7 41.9 177.7 98.7 240.8 67.7 215.3 156.2 45.4 125.1 58.3 142.7 232.4 113.0 1.7 25.7 12.5 5.2 28.1 2.8 3.5 4.8 4.9 18.1 3.3 3.4 5.3 3.6 2.1 20.8 7.0 3.1 14.5 5.9 6.9 7.9 8.4 7.1 9.1 12.1 9.3 12.3 7.6 18.9 12.6 35.0 19.2 23.5 11.1 10.3 19.5 7.0 10.4 10.8 3.7 8.8 9.5 11.2 10.0 15.5 11.0 6.2 7.9 28.6 14.7 0.0 13.1 3.6 8.5 28.5 29.3 5.4 10.3 10.9 8.2 76.2 30.9 20.9 13.6 8.8 20.3 7.9 14.2 91.0 13.5 9.9 15.1 4.1 70.7 24.1 3.1 19.0 59.6 17.8 19.7 26.6 2.3 10.3 6.6 12.8 10.4 7.6 21.8 6.0 9.5 9.5 4.4 8.7 3.6 13.1 9.5 24.3 2.5 13.1 13.8 20.9 8.3 12.0 24.9 18.2 8.4 COMMD9 "FLJ31106, HSPC166" ENSG00000110442 "COMM domain containing 9" Q9P000 11 36269284-36289449 "Predicted intracellular proteins" "Ion transport, Sodium transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009142 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA009142: AB_1847105" "unprognostic (1.56e-2)" "unprognostic (4.75e-3)" "unprognostic (7.57e-2)" "unprognostic (4.40e-3)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-3)" "unprognostic (2.62e-1)" "unprognostic (6.15e-2)" "prognostic favorable (8.54e-4)" "unprognostic (4.94e-2)" "unprognostic (2.40e-1)" "unprognostic (6.08e-3)" "unprognostic (7.24e-2)" "unprognostic (1.71e-1)" "unprognostic (7.31e-3)" "unprognostic (1.88e-1)" 26.8 32.1 33.8 21.8 34.1 50.8 24.3 35.1 36.7 17.2 29.6 19.6 21.1 14.1 25.1 24.9 20.3 20.5 31.1 33.8 33.8 38.7 36.6 26.8 26.0 34.2 34.4 19.4 26.4 27.4 23.2 24.8 33.9 14.0 24.2 20.3 21.9 13.3 64.2 27.1 20.2 21.9 36.9 26.8 19.7 14.9 36.0 30.6 25.1 61.7 32.0 20.6 16.6 39.1 28.8 33.4 36.1 38.2 54.5 37.8 20.0 33.6 42.6 74.7 69.8 27.3 23.9 33.0 32.5 67.1 57.5 41.4 64.0 45.2 69.6 39.9 75.2 18.2 57.6 48.0 51.0 71.6 52.3 48.0 49.5 40.9 25.0 38.5 62.2 43.3 45.7 34.7 59.4 36.9 47.9 49.6 38.5 55.6 70.3 52.1 81.7 38.9 78.6 26.6 44.1 49.2 47.9 47.1 43.6 29.2 102.7 27.0 41.9 45.0 34.4 107.9 49.8 24.3 53.2 37.2 51.8 66.4 44.0 85.6 376.6 173.7 91.4 359.0 86.8 130.7 87.5 88.4 383.6 138.3 99.8 83.4 42.7 94.8 300.9 145.8 114.5 315.2 33.8 34.1 35.1 36.7 33.8 33.8 34.2 34.4 33.9 36.9 36.0 39.1 26.9 22.4 29.4 2.6 27.0 15.3 12.7 37.4 13.1 16.6 25.6 38.7 29.9 12.8 20.2 18.4 10.4 43.2 28.3 16.9 78.2 70.1 9.5 13.2 20.3 22.8 25.7 23.1 9.4 46.4 52.9 21.2 11.7 17.0 19.0 25.6 15.4 17.1 105.1 5.0 8.7 20.4 34.6 59.5 35.6 28.9 17.7 57.5 24.9 1.9 61.3 36.3 33.0 4.5 8.8 46.5 17.7 11.7 10.4 4.9 30.3 62.5 8.5 22.9 13.1 12.3 22.8 32.8 33.3 19.6 21.6 24.9 19.2 28.4 24.6 12.0 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CREBL2 ENSG00000111269 "CAMP responsive element binding protein like 2" O60519 12 12611827-12645108 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 130.6" "Cell type enhanced" "Detected in all" "Kupffer cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043738 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Nucleoplasm, Cytosol" "HPA043738: AB_10795041" "unprognostic (2.87e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" "unprognostic (7.51e-2)" "unprognostic (7.38e-2)" "unprognostic (4.51e-1)" "unprognostic (1.44e-1)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (5.82e-3)" "unprognostic (6.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (6.31e-2)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.53e-1)" 39.8 130.6 24.7 30.4 26.3 5.3 31.9 22.8 29.2 26.4 29.5 23.4 23.1 19.0 28.8 17.1 24.6 28.2 22.5 26.2 28.8 49.7 50.1 32.5 37.5 24.6 24.5 37.2 24.7 56.3 32.2 24.2 24.6 28.2 23.8 35.2 26.4 23.0 10.1 24.6 23.6 18.9 24.8 37.5 25.1 20.9 29.1 24.7 44.3 15.6 29.8 28.0 15.1 27.7 12.5 15.9 13.6 15.5 46.9 47.0 26.3 24.0 40.4 17.3 23.7 11.5 17.9 10.8 9.1 29.3 26.2 10.3 20.7 18.4 29.1 61.0 12.6 8.5 15.1 14.2 30.7 12.2 15.2 30.8 32.2 20.3 33.1 58.7 25.7 8.5 8.7 16.5 29.4 20.1 6.4 9.9 40.8 11.9 14.4 8.7 23.6 6.9 33.1 35.7 16.0 18.2 24.4 11.7 43.3 58.5 6.5 13.6 20.8 23.7 15.1 23.7 23.9 13.9 19.7 2.7 28.1 10.3 24.9 1.1 2.5 2.6 1.7 5.6 3.1 0.9 3.4 2.7 2.8 1.1 3.3 2.7 0.4 1.1 2.6 1.4 5.6 1.5 24.7 26.3 22.8 29.2 26.2 28.8 24.6 24.5 24.6 24.8 29.1 27.7 18.0 25.6 26.5 23.5 14.8 22.2 18.6 11.1 18.8 17.5 23.5 15.9 14.6 30.0 12.2 33.1 2.1 18.1 15.7 17.7 41.1 21.6 40.4 14.2 10.4 19.1 30.0 27.8 15.9 21.8 19.3 25.3 17.9 10.6 10.2 12.1 23.2 48.4 39.3 37.0 17.7 16.4 26.4 120.0 83.0 12.1 36.1 58.2 33.8 33.7 45.6 38.0 10.3 28.6 18.6 21.8 15.0 35.3 17.3 29.5 29.3 58.8 19.9 11.8 39.5 13.7 12.4 45.8 20.8 18.0 29.1 27.5 23.3 11.5 17.6 28.1 CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 545.7;Kupffer cells: 559.7;monocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Cell line enhanced" "Detected in all" "RPMI-8226: 1237.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" 130.5 127.7 37.5 79.0 41.1 125.9 109.7 39.0 45.9 76.8 47.8 77.1 60.3 61.8 109.7 91.7 70.9 128.2 82.2 36.5 40.4 132.1 295.2 99.1 98.9 46.0 39.1 84.2 70.7 75.4 64.8 110.8 44.4 62.9 82.7 80.0 104.5 74.6 71.4 109.8 63.0 77.9 45.7 136.9 61.4 50.1 49.3 35.5 125.8 78.2 63.5 116.3 63.3 61.2 93.5 41.5 21.1 43.5 325.8 89.8 53.0 39.2 17.8 30.7 39.8 67.8 104.4 101.7 112.2 43.6 57.2 143.3 24.3 84.9 20.9 140.3 82.3 41.5 31.1 37.9 111.5 93.6 295.2 94.5 250.5 35.6 38.7 42.7 10.3 35.9 218.5 405.0 42.6 39.2 19.6 95.9 22.8 214.0 63.9 32.5 58.8 1237.2 54.7 64.9 14.0 25.7 98.1 132.8 112.8 70.1 175.5 252.7 19.1 8.0 39.6 126.2 25.9 79.4 168.4 67.7 131.6 96.0 16.3 55.4 128.4 75.7 5.1 75.7 8.0 4.3 7.5 6.5 89.9 2.1 16.6 8.8 43.7 11.0 72.3 6.2 3.9 57.6 37.5 41.1 39.0 45.9 36.5 40.4 46.0 39.1 44.4 45.7 49.3 61.2 44.7 35.3 90.1 5.9 15.3 44.1 49.1 23.1 56.9 17.9 61.7 63.8 55.7 65.8 32.2 55.2 89.6 91.5 18.3 15.6 23.5 36.0 27.6 33.9 19.3 34.2 29.3 124.8 24.7 39.7 41.7 78.4 21.9 64.1 29.9 62.0 48.2 90.3 545.7 15.2 22.1 44.5 14.2 559.7 57.6 27.4 43.5 213.8 24.9 26.2 322.8 30.5 6.2 10.1 14.6 21.0 31.5 28.6 27.8 34.0 46.3 60.6 18.5 31.5 13.1 43.2 40.8 65.5 42.0 86.3 51.1 126.7 17.3 38.9 50.4 44.0 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6" "Cell type enriched" "Detected in some" 21 "Hofbauer cells: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Group enriched" "Detected in some" 5 "Karpas-707: 43.3;RPMI-8226: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 1.3 1.6 1.5 0.9 1.6 0.6 0.6 1.6 2.4 0.6 1.3 0.5 0.4 0.3 9.6 0.4 0.4 1.2 0.4 1.6 1.6 0.2 0.4 0.5 1.2 1.9 1.8 0.2 0.2 0.3 0.5 3.3 2.3 0.2 0.4 0.0 0.4 0.2 0.1 0.1 0.4 0.9 1.9 1.6 0.3 0.3 2.2 0.4 0.2 0.2 0.5 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.3 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 0.0 82.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.2 0.5 0.0 0.0 0.7 0.2 1.8 0.0 2.2 0.0 0.0 1.0 0.0 0.0 10.3 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.5 7.5 0.0 0.0 0.6 1.5 1.6 1.6 2.4 1.6 1.6 1.9 1.8 2.3 1.9 2.2 2.1 0.1 0.0 0.0 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.1 1.3 0.0 0.0 0.2 82.6 0.0 0.2 0.0 0.0 3.5 0.8 0.6 0.0 2.8 1.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.2 0.0 0.0 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CTNS "CTNS-LSB, PQLC4, SLC66A4" ENSG00000040531 "Cystinosin, lysosomal cystine transporter" O60931 17 3636459-3663103 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Protein transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 35.5;Late spermatids: 29.3;Theca cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.3;granulocytes: 27.9;monocytes: 10.4" "Cell line enhanced" "Detected in all" "HDLM-2: 144.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046947 Supported "Vesicles,Intermediate filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Intermediate filaments" "HPA046947: AB_2679872" "unprognostic (1.64e-1)" "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" "unprognostic (8.25e-2)" "unprognostic (8.39e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.28e-2)" "unprognostic (8.02e-2)" "unprognostic (1.94e-1)" "unprognostic (6.62e-3)" "prognostic favorable (6.39e-5)" "unprognostic (8.40e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" 10.3 19.5 9.5 10.0 17.0 10.2 9.6 13.5 12.1 20.3 12.1 8.3 12.2 11.3 6.4 8.7 10.3 13.1 10.5 10.8 10.3 15.2 15.9 11.6 10.0 16.5 16.8 12.1 27.0 13.6 9.6 12.9 18.0 10.8 7.2 6.8 12.0 11.6 15.3 19.2 11.0 8.6 10.9 12.1 15.0 24.8 13.2 8.8 9.2 7.4 9.5 9.1 9.4 28.0 17.6 37.0 22.6 18.2 34.5 16.9 13.0 19.6 28.8 21.1 26.0 21.0 16.0 10.2 17.8 11.6 55.9 40.1 19.8 12.1 12.6 144.3 33.7 10.8 32.2 19.3 46.5 8.0 81.3 23.8 14.2 20.2 15.4 28.1 22.2 18.7 12.6 15.9 16.6 15.1 7.8 7.9 9.8 12.2 16.8 16.4 9.3 23.0 15.3 16.2 3.9 17.2 19.2 24.4 20.3 19.0 17.1 7.7 24.2 17.2 11.6 40.3 13.3 12.4 20.0 4.2 28.1 7.8 11.8 27.9 10.4 21.8 3.0 6.9 4.9 5.8 4.0 5.7 9.7 4.9 4.5 5.5 3.1 5.2 7.1 34.3 4.3 7.3 9.5 17.0 13.5 12.1 10.8 10.3 16.5 16.8 18.0 10.9 13.2 28.0 4.4 3.2 2.2 6.5 4.8 1.7 3.5 2.5 4.0 1.6 6.3 5.0 5.2 5.7 2.7 12.9 10.4 6.1 5.2 3.6 0.0 6.7 35.5 5.7 4.4 5.3 2.4 4.0 3.4 6.4 7.1 6.0 7.7 4.3 8.2 6.7 9.3 7.6 25.2 5.0 3.4 2.5 4.1 7.2 5.9 29.3 9.6 12.1 5.4 3.7 10.0 6.5 3.1 5.5 11.1 6.4 3.3 12.8 4.5 6.5 3.2 9.5 7.0 3.9 6.6 3.7 3.5 19.7 8.7 2.9 2.4 8.5 3.3 30.9 1.8 3.2 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1475.9;Hofbauer cells: 3763.5;Macrophages: 1512.6;Proximal enterocytes: 1699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 2596.6;hTERT-RPE1: 2780.1;SK-BR-3: 2488.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 318.6 734.6 147.0 204.9 181.9 499.0 244.0 186.0 156.5 270.8 672.7 298.0 387.6 170.7 82.8 319.4 171.6 438.4 444.1 187.8 223.6 691.6 464.8 539.6 241.0 247.6 206.6 130.7 284.8 137.3 131.5 180.7 228.6 138.2 153.4 48.3 422.1 231.7 590.3 340.9 398.3 105.0 188.9 442.0 287.2 88.9 334.4 78.1 182.1 178.2 123.1 296.4 307.5 367.1 204.6 578.9 51.4 246.2 586.5 206.3 112.1 149.4 362.2 161.8 182.8 147.5 2596.6 49.2 376.8 285.8 1265.6 1072.2 63.7 142.6 35.8 206.7 222.9 70.4 92.5 196.5 736.2 171.4 787.7 350.9 621.6 82.5 136.9 2780.1 128.2 62.1 89.2 267.6 263.3 832.6 47.0 110.9 153.1 719.7 247.9 62.5 72.5 191.2 586.6 610.8 84.2 94.8 173.3 2488.5 535.0 68.6 1022.8 232.6 170.3 556.8 92.9 79.0 216.7 432.0 382.3 26.8 867.7 468.6 509.6 211.2 578.7 170.1 156.5 309.9 90.6 28.8 72.1 110.3 144.5 18.8 82.5 107.4 319.5 192.3 265.2 120.3 89.2 489.1 147.0 181.9 186.0 156.5 187.8 223.6 247.6 206.6 228.6 188.9 334.4 367.1 139.3 112.2 228.6 48.3 62.8 72.0 223.5 473.2 71.7 168.6 108.9 113.8 251.9 314.5 459.5 548.1 110.5 211.7 156.1 1475.9 109.5 911.4 3.3 118.1 67.4 128.3 159.6 132.6 18.3 370.1 165.0 157.0 237.5 203.4 474.3 119.4 695.7 678.9 3763.5 264.2 25.2 418.2 498.5 1187.8 67.5 14.6 108.4 1512.6 227.7 20.6 382.6 179.0 256.4 27.2 42.2 392.3 832.5 128.2 122.5 111.7 1699.4 311.8 270.3 102.1 111.7 70.7 135.2 26.6 63.5 141.2 82.1 471.3 155.0 96.0 399.1 357.8 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CXCL5 "ENA-78, SCYB5" ENSG00000163735 "C-X-C motif chemokine ligand 5" P42830 4 73995642-73998677 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 35.9;salivary gland: 50.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 64.6;Ductal cells: 94.0;Macrophages: 222.6;Pancreatic endocrine cells: 245.4" "Group enriched" "Detected in many" 4 "pancreatic cancer: 56.2;stomach cancer: 74.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 191.9;EFO-21: 157.0;HSkMC: 111.4;hTEC/SVTERT24-B: 81.6;RPTEC TERT1: 603.6" HPA065474 Approved Approved Vesicles "Secreted to blood" NA NA 1110000 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA065474: AB_2685494" "unprognostic (5.56e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.43e-2)" "unprognostic (2.04e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.06e-2)" "unprognostic (3.04e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (7.99e-2)" "prognostic unfavorable (2.45e-5)" "unprognostic (3.72e-1)" "unprognostic (3.07e-1)" "unprognostic (2.72e-2)" "unprognostic (9.30e-2)" 2.1 0.2 1.5 35.9 0.9 1.2 3.2 0.6 8.8 7.7 0.4 0.7 0.8 0.2 0.0 0.1 0.2 4.8 0.6 0.8 2.6 0.2 1.3 10.0 6.3 1.4 2.1 0.0 0.5 0.0 0.1 0.2 3.1 1.3 0.3 0.0 50.2 0.5 0.1 0.0 2.1 0.2 1.1 2.1 8.5 0.4 5.7 0.6 0.0 0.2 0.6 8.4 0.0 0.7 0.1 191.9 0.7 0.0 0.3 6.9 0.0 3.5 2.9 1.5 3.0 0.6 1.6 0.0 157.0 0.1 34.0 0.4 0.0 0.0 17.6 0.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 111.4 0.0 81.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 603.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.5 0.0 1.0 0.0 0.1 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.0 1.5 0.9 0.6 8.8 0.8 2.6 1.4 2.1 3.1 1.1 5.7 0.7 0.2 3.2 0.0 0.0 0.0 0.9 0.7 64.6 0.0 0.0 8.0 4.4 1.2 15.7 33.2 0.0 0.0 0.0 0.1 1.3 0.0 94.0 0.7 0.7 0.1 1.8 0.0 0.0 0.3 1.4 0.1 3.6 15.3 1.2 0.0 0.0 0.7 0.0 0.5 0.0 0.3 0.7 4.1 0.3 30.4 0.3 0.0 222.6 0.0 1.0 2.1 0.0 0.0 0.0 0.1 245.4 0.0 0.0 0.3 3.1 0.0 0.1 4.3 0.0 0.0 0.6 4.0 0.1 0.6 0.0 0.3 0.0 0.3 0.0 1.1 2.0 CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 1632.1;Hofbauer cells: 2171.9;Kupffer cells: 1734.2;Macrophages: 1682.8;monocytes: 1688.5;NK-cells: 1805.4;Plasma cells: 1990.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 1058.3;RPMI-8226: 1631.2;THP-1: 1231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009492 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009492: AB_2090309" "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" 149.9 68.0 40.3 344.4 41.8 742.0 93.3 46.0 58.0 81.9 62.4 200.9 196.6 60.8 38.5 80.9 95.4 122.5 93.2 38.6 55.0 187.7 71.5 234.6 333.8 73.8 49.3 40.0 108.6 13.4 40.6 54.9 64.1 75.2 79.9 1.8 116.7 26.6 41.8 39.4 245.3 51.3 65.4 693.1 236.0 10.4 62.4 87.1 136.5 19.9 192.8 144.6 74.1 92.2 2.5 663.0 2.6 1.5 1.3 0.4 329.5 155.7 77.3 39.3 24.1 447.2 819.6 510.5 420.7 56.4 0.0 250.5 21.4 0.9 5.8 146.1 564.1 99.0 217.7 694.9 75.7 156.3 397.6 80.7 0.0 1.6 0.3 1.9 23.9 103.6 278.5 567.5 3.2 1058.3 147.9 822.3 106.2 248.7 1.5 437.9 1.6 1631.2 324.9 490.9 84.2 76.5 482.7 78.8 138.5 60.8 1.4 1231.3 129.8 1.5 6.1 1.8 2.2 362.9 459.9 543.6 195.5 464.9 53.4 120.2 103.8 733.7 76.7 150.1 55.8 109.8 36.7 70.4 107.0 110.7 28.9 36.7 192.3 36.4 143.3 196.3 41.2 47.3 40.3 41.8 46.0 58.0 38.6 55.0 73.8 49.3 64.1 65.4 62.4 92.2 157.8 16.0 12.4 0.0 1290.9 119.4 233.4 420.8 53.5 0.4 131.7 133.2 12.8 368.9 487.1 285.1 2.1 45.3 1632.1 807.2 127.2 636.8 4.2 219.5 137.5 137.1 230.5 162.7 0.2 155.3 299.0 184.8 285.4 312.5 279.0 104.3 317.0 23.9 2171.9 0.0 0.2 540.3 233.9 1734.2 1370.8 14.0 50.1 1682.8 1152.6 32.8 1688.5 1.6 1805.4 1.0 0.2 682.8 1045.8 21.4 1990.6 191.8 390.4 1057.4 529.7 2.7 59.2 44.0 164.3 0.9 15.6 75.2 85.7 118.2 838.6 20.5 805.2 436.9 DCANP1 "C5orf20, DCNP1" ENSG00000251380 "Dendritic cell associated nuclear protein" Q8TF63 5 135444214-135447348 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Microglial cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "THP-1: 1.8" HPA048308 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nuclear bodies" "HPA048308: AB_2680349" 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DCSTAMP "DC-STAMP, FIND, TM7SF4" ENSG00000164935 "Dendrocyte expressed seven transmembrane protein" Q9H295 8 104339087-104356689 "Predicted membrane proteins, Transporters" "Differentiation, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 4.5;epididymis: 2.0;lung: 3.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 7.1;Macrophages: 6.5" "Cancer enriched" "Detected in some" 46 "thyroid cancer: 45.3" "Group enriched" "Detected in some" 4 "amygdala: 4.5;basal ganglia: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.11e-2)" "unprognostic (1.22e-2)" "unprognostic (8.41e-2)" "unprognostic (2.96e-2)" "unprognostic (8.48e-4)" "unprognostic (2.14e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-2)" "unprognostic (3.08e-2)" "unprognostic (1.18e-2)" "unprognostic (5.26e-2)" "unprognostic (2.45e-1)" "unprognostic (1.61e-3)" "unprognostic (8.84e-2)" "unprognostic (1.36e-1)" "unprognostic (8.05e-2)" "unprognostic (8.34e-3)" 0.8 0.0 4.5 0.1 2.6 0.2 0.3 0.0 0.8 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.8 0.1 0.0 0.4 3.8 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.5 2.6 0.0 0.8 0.8 0.1 0.0 0.1 0.1 0.0 0.8 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DNASE1L1 "DNAS1L1, DNASEX, DNL1L, XIB" ENSG00000013563 "Deoxyribonuclease 1 like 1" P49184 X 154401236-154412112 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 147.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072635 Approved "Intracellular and membrane" NA NA 96000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA072635: AB_2686542" "unprognostic (5.27e-2)" "unprognostic (1.95e-1)" "unprognostic (4.57e-3)" "unprognostic (2.97e-1)" "unprognostic (1.27e-2)" "unprognostic (1.59e-3)" "unprognostic (3.82e-2)" "unprognostic (3.08e-2)" "unprognostic (2.88e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (4.98e-1)" "prognostic favorable (2.19e-4)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "unprognostic (6.75e-2)" 18.7 26.6 12.6 13.0 12.1 24.1 17.8 11.7 14.1 15.8 26.6 15.2 15.2 15.8 22.5 21.6 14.0 13.0 43.2 13.5 14.3 20.9 18.8 22.0 16.4 12.2 13.4 13.7 12.8 22.7 20.1 16.1 12.6 15.1 12.3 3.9 22.0 11.3 147.0 11.3 19.3 11.3 13.0 28.5 18.1 7.7 13.6 8.9 24.1 94.8 13.2 13.5 16.9 11.9 19.7 19.6 6.3 12.2 56.6 74.5 7.7 54.5 85.3 17.6 34.6 5.7 28.0 32.9 68.2 103.0 67.4 9.6 7.6 31.0 12.8 9.9 13.0 4.8 20.6 7.1 38.8 8.6 33.4 55.6 35.7 39.6 40.0 47.9 76.4 5.3 6.5 34.0 61.1 33.0 3.6 4.2 5.0 35.5 22.1 7.3 28.5 52.9 31.0 9.7 20.2 12.0 17.1 29.9 22.5 13.9 11.9 7.8 112.9 17.7 20.3 25.6 10.9 64.2 15.4 34.4 26.6 14.4 22.4 13.0 12.0 17.1 3.5 21.6 4.0 6.2 3.3 3.1 14.5 4.1 2.4 2.2 7.0 4.6 20.9 8.3 4.9 6.4 12.6 12.1 11.7 14.1 13.5 14.3 12.2 13.4 12.6 13.0 13.6 11.9 20.1 6.4 6.5 3.3 8.0 1.3 7.1 11.1 9.6 1.8 5.1 3.8 2.0 5.7 5.4 5.5 0.0 5.3 6.7 15.5 9.8 6.1 0.1 5.8 5.7 17.7 6.1 6.5 3.2 10.2 23.3 5.2 11.7 7.5 13.3 4.9 23.2 8.6 29.1 0.0 2.2 10.4 6.1 36.6 11.7 1.2 3.4 25.4 16.0 4.7 22.9 12.8 7.2 0.0 0.5 13.5 18.1 2.6 6.8 5.9 27.0 9.6 7.0 1.4 0.0 16.7 3.3 0.4 0.4 10.4 1.7 8.9 6.0 3.2 10.9 10.9 DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875209-12881466 "Enzymes, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 226.7;Paneth cells: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" NA NA 560000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA066185: AB_2685632" "unprognostic (9.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.97e-2)" "unprognostic (7.45e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (5.42e-2)" "unprognostic (4.85e-2)" "unprognostic (1.40e-1)" "unprognostic (5.12e-2)" "unprognostic (4.37e-2)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" 27.0 26.7 17.1 24.0 17.5 9.6 23.3 17.2 19.1 22.7 19.7 24.7 23.7 25.1 29.5 18.9 25.3 25.3 22.7 16.5 17.6 19.2 36.0 37.7 42.2 18.7 18.2 26.1 41.7 43.1 23.8 20.6 19.4 27.7 19.2 5.6 33.0 26.1 19.7 29.2 22.7 22.0 19.3 26.2 30.0 5.9 17.8 20.8 38.7 13.1 26.5 24.3 19.9 23.0 63.7 36.3 2.9 80.8 86.8 46.2 55.0 34.4 87.2 33.2 79.6 3.8 43.6 27.9 97.3 54.9 73.0 71.8 30.7 33.2 16.2 89.8 41.0 13.1 36.8 17.5 68.3 26.5 119.8 46.5 74.5 24.8 36.7 80.2 50.2 42.4 14.0 112.1 20.3 82.7 27.3 14.1 6.1 66.3 60.8 17.1 14.2 64.3 32.9 29.7 17.3 28.6 46.1 65.8 123.5 11.8 98.5 23.4 32.5 67.8 21.4 70.3 31.1 139.9 153.6 35.7 112.9 24.6 34.4 73.5 71.0 10.9 64.5 95.8 53.5 31.1 56.1 68.8 14.0 35.6 49.0 53.7 40.6 70.9 114.2 28.3 85.8 66.4 17.1 17.5 17.2 19.1 16.5 17.6 18.7 18.2 19.4 19.3 17.8 23.0 18.7 25.6 22.4 7.5 25.5 14.5 23.6 56.9 14.2 6.7 22.7 18.5 10.6 28.6 31.0 36.8 4.2 60.0 23.5 17.3 3.9 67.1 0.5 24.1 15.1 21.4 16.4 5.7 1.3 58.3 96.2 27.9 13.7 25.4 22.2 23.8 28.9 26.4 226.7 5.0 1.7 15.0 83.4 87.5 6.8 2.5 32.0 55.5 46.2 2.8 28.4 32.2 33.0 3.0 1.7 39.5 125.0 33.4 36.6 15.1 10.8 6.8 29.9 3.3 13.1 16.5 16.9 0.6 4.8 12.4 12.4 48.0 23.9 23.0 26.2 18.5 DNASE2B DLAD ENSG00000137976 "Deoxyribonuclease 2 beta" Q8WZ79 1 84398484-84415018 "Enzymes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 25 "salivary gland: 170.3" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Hofbauer cells: 5.8;Kupffer cells: 1.6;Late spermatids: 3.1;Macrophages: 4.2;Paneth cells: 1.7;Prostatic glandular cells: 2.0" "Group enriched" "Detected in some" 5 "melanoma: 2.8;prostate cancer: 9.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.24e-1)" "unprognostic (3.57e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-1)" "unprognostic (2.86e-1)" "unprognostic (1.62e-2)" "unprognostic (9.87e-2)" "unprognostic (7.90e-2)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (3.82e-5)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "unprognostic (6.79e-2)" "unprognostic (3.08e-3)" 0.6 0.1 0.3 0.0 0.6 0.0 0.4 0.3 0.8 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.0 0.3 2.4 0.7 0.5 0.3 0.1 0.8 0.0 0.3 0.0 0.6 6.8 0.5 0.0 170.3 0.0 1.6 0.0 0.1 0.0 0.4 0.4 0.8 0.4 0.4 0.2 0.1 0.2 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.8 0.4 1.0 0.5 0.3 0.6 0.4 0.4 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 5.8 0.0 0.4 0.1 0.0 1.6 0.0 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 1.7 0.0 0.1 2.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 DOK1 p62dok ENSG00000115325 "Docking protein 1" Q99704 2 74549026-74557551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 36.8;Hofbauer cells: 48.6;Macrophages: 31.2;monocytes: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004224, HPA048561" Approved Supported Cytosol NA NA 80000 "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB004224: AB_627447, HPA048561: AB_2680443" "unprognostic (2.40e-2)" "unprognostic (2.07e-2)" "unprognostic (2.60e-1)" "prognostic favorable (8.42e-4)" "unprognostic (9.86e-3)" "unprognostic (1.28e-1)" "unprognostic (7.10e-2)" "prognostic favorable (4.64e-4)" "unprognostic (7.57e-2)" "unprognostic (1.85e-2)" "unprognostic (1.89e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (3.16e-6)" "unprognostic (8.65e-2)" "unprognostic (2.40e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-2)" 10.8 3.7 8.8 10.2 8.3 13.7 4.7 8.2 9.0 6.6 7.6 5.2 4.4 4.9 0.7 1.4 6.3 3.2 2.8 7.8 8.7 2.7 1.5 6.6 12.3 10.7 8.7 4.2 3.7 6.3 2.2 4.0 9.2 3.1 3.8 0.9 3.0 4.0 1.1 1.6 5.8 4.8 9.2 11.6 6.7 1.7 9.4 7.6 3.9 1.7 10.1 4.7 2.7 9.0 5.3 2.0 6.0 3.0 13.9 16.8 4.2 12.8 10.0 5.2 8.5 1.6 6.1 3.3 18.0 12.3 11.3 0.7 6.1 2.8 1.9 76.3 5.7 43.1 4.4 0.3 10.0 22.0 41.0 12.5 0.0 28.5 14.7 21.7 6.2 13.8 12.7 9.5 10.5 5.6 15.8 45.7 11.1 10.8 1.6 13.0 12.9 3.5 2.7 4.5 2.0 10.0 2.5 0.7 6.7 1.7 3.3 24.1 11.7 32.7 15.1 15.3 2.9 12.6 9.6 0.1 32.9 35.3 5.5 39.0 52.3 38.9 17.3 51.4 13.9 22.9 14.1 15.4 51.3 26.3 10.3 10.3 52.9 27.4 59.3 10.8 24.3 39.8 8.8 8.3 8.2 9.0 7.8 8.7 10.7 8.7 9.2 9.2 9.4 9.0 6.7 9.6 8.8 2.9 15.0 2.0 1.1 3.7 1.2 0.5 2.2 2.8 1.8 4.3 2.0 5.5 0.0 1.9 13.6 8.7 0.0 11.9 0.3 7.4 5.8 7.2 3.0 12.4 0.1 9.1 4.2 6.5 6.1 5.6 36.8 5.8 9.7 0.6 48.6 1.7 0.5 5.9 2.0 26.3 24.2 1.0 5.0 31.2 3.6 4.7 41.1 9.8 16.5 0.5 0.6 10.2 10.0 6.0 6.3 2.4 8.1 3.9 1.7 0.5 6.6 4.1 8.3 0.5 2.1 0.3 1.6 2.3 13.5 7.0 6.8 1.6 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 232.8;placenta: 489.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 863.3;Langerhans cells: 205.1;Macrophages: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.1;myeloid DC: 179.6" "Group enriched" "Detected in many" 184 "dendritic cells: 179.6;granulocytes: 50.2;monocytes: 141.1" "Cell line enhanced" "Detected in some" "AF22: 24.0;LHCN-M2: 8.9;RH-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 4: Macrophages - Innate immune response" "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 232.8 57.9 2.6 52.3 4.2 16.1 46.9 1.3 13.0 50.4 28.5 45.9 9.7 18.5 5.6 51.2 29.1 52.7 39.2 2.1 3.6 21.0 3.0 38.7 30.0 8.3 4.6 10.7 10.0 13.3 8.1 489.2 6.9 8.8 63.9 21.6 18.8 13.4 10.3 22.7 22.0 89.6 2.6 8.8 25.4 17.8 3.7 20.9 17.1 32.8 12.5 144.5 12.1 4.0 0.0 0.1 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 43.8 0.8 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 50.2 141.1 1.4 0.5 25.4 0.6 0.4 0.3 0.4 179.6 0.4 0.4 0.2 32.9 0.3 0.7 12.5 0.3 364.9 2.6 4.2 1.3 13.0 2.1 3.6 8.3 4.6 6.9 2.6 3.7 4.0 2.0 0.0 1.9 0.3 1.8 18.7 0.0 0.0 0.6 0.1 0.3 0.4 10.6 5.7 0.0 0.0 0.0 5.0 4.5 0.0 0.0 0.0 5.1 0.6 10.6 3.8 0.0 1.3 3.9 0.0 5.6 13.7 0.0 0.4 1.3 0.0 2.9 0.9 863.3 0.0 1.4 0.0 0.0 92.4 205.1 5.8 4.4 232.0 19.6 64.6 53.1 0.9 6.2 0.5 0.7 0.1 0.0 0.7 1.2 0.0 0.0 11.0 2.2 6.5 59.2 2.5 3.3 1.6 0.9 1.2 15.2 10.1 2.6 0.4 0.0 0.1 FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C golgi associated secretory pathway kinase" Q8IXL6 7 192571-260772 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 55.2;Hepatocytes: 94.0;Hofbauer cells: 54.9;Peritubular cells: 56.4;Proximal tubular cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 55.3;hTERT-RPE1: 39.9;U-87 MG: 36.0;WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Approved "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" NA NA 240000000 "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.94e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (3.15e-2)" "unprognostic (1.03e-2)" "unprognostic (3.33e-3)" "unprognostic (2.47e-2)" "unprognostic (7.86e-2)" "unprognostic (2.45e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (9.40e-6)" "unprognostic (1.97e-3)" "unprognostic (2.49e-1)" "unprognostic (3.08e-3)" "unprognostic (1.94e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (3.83e-3)" 32.5 14.8 7.0 7.3 5.7 1.5 32.8 5.0 7.0 19.4 0.8 44.3 4.5 19.4 2.1 14.3 20.2 5.9 30.2 4.3 5.0 34.9 56.5 27.9 1.1 12.5 9.7 20.3 13.4 1.6 18.3 2.6 6.7 29.9 1.4 1.1 20.3 3.6 30.7 14.7 23.3 6.8 6.4 8.9 38.9 7.8 12.6 0.6 19.6 6.3 0.6 36.8 15.1 6.2 19.6 6.4 0.3 10.3 11.8 20.3 0.0 17.4 23.2 7.9 5.9 0.9 10.1 0.0 9.3 21.8 10.4 14.9 1.1 0.6 1.6 4.5 0.6 0.0 3.1 3.4 8.8 0.0 1.0 55.3 1.6 0.3 0.7 39.9 5.0 0.0 0.0 0.0 1.8 1.9 0.0 0.7 8.9 0.1 0.3 2.3 0.5 0.0 4.9 0.0 4.4 0.2 17.2 0.0 2.3 1.1 9.7 6.5 14.6 10.3 5.3 7.7 5.3 0.0 0.0 0.0 36.0 1.0 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 5.7 5.0 7.0 4.3 5.0 12.5 9.7 6.7 6.4 12.6 6.2 5.0 6.4 5.1 11.8 1.2 10.1 2.3 4.5 1.8 26.9 27.6 18.7 9.9 21.5 1.0 55.2 0.0 0.5 4.6 3.4 5.9 1.8 0.0 4.1 19.0 4.5 11.9 0.4 7.4 4.8 0.5 22.6 13.7 9.5 3.8 3.1 9.3 94.0 54.9 1.7 17.0 5.3 2.0 24.4 9.8 2.6 16.1 34.5 1.8 5.6 10.8 17.1 0.0 8.5 15.3 6.3 3.7 56.4 0.1 6.6 33.7 48.7 3.4 9.0 13.1 8.7 17.3 0.3 1.0 3.5 8.1 0.5 0.9 0.6 9.0 1.9 FCER1G ENSG00000158869 "Fc fragment of IgE receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.6;lymphoid tissue: 470.1" "Group enriched" "Detected in many" 9 "dendritic cells: 726.6;granulocytes: 705.6;Hofbauer cells: 2318.6;Kupffer cells: 1950.8;Langerhans cells: 1526.3;Macrophages: 1971.3;monocytes: 808.9;NK-cells: 1037.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 1987.3;classical monocyte: 3240.2;intermediate monocyte: 5333.6;myeloid DC: 2386.3;neutrophil: 1831.0;NK-cell: 1750.9;non-classical monocyte: 6984.5;plasmacytoid DC: 3315.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "HEL: 77.8;HMC-1: 301.7;THP-1: 276.1;U-266/84: 90.1;U-937: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" 251.7 86.5 34.0 275.6 33.8 441.6 62.9 35.5 66.0 52.5 47.5 82.7 44.9 30.7 38.7 30.6 72.0 101.5 53.1 33.7 42.0 40.3 177.3 286.6 160.9 53.4 48.7 19.9 22.3 26.8 26.9 211.0 50.1 31.0 113.2 8.3 42.9 38.8 11.9 21.0 60.6 160.3 41.5 470.1 39.4 14.5 49.9 62.7 25.5 34.6 82.5 254.6 21.7 65.4 0.2 0.0 0.7 1.3 1.8 0.7 0.4 0.5 0.2 0.5 0.8 2.2 0.1 0.5 0.7 0.0 0.3 0.2 0.5 0.0 0.4 0.3 1.5 77.8 0.6 14.0 0.3 16.1 301.7 6.0 3.3 2.3 0.2 0.7 0.4 1.8 0.1 7.3 2.4 0.5 1.4 37.9 1.6 0.0 0.0 0.1 6.7 0.2 0.5 0.4 0.3 1.0 0.6 0.1 2.7 1.4 0.2 276.1 0.4 1.8 0.4 0.9 1.1 3.0 90.1 0.9 1.7 87.1 0.5 1987.3 3240.2 307.3 13.6 5333.6 15.9 28.2 10.6 10.6 2386.3 9.0 17.3 45.0 1831.0 1750.9 6984.5 3315.6 21.8 4265.5 34.0 33.8 35.5 66.0 33.7 42.0 53.4 48.7 50.1 41.5 49.9 65.4 12.8 86.6 147.7 0.7 35.9 39.6 1.5 0.2 1.8 0.1 5.2 22.1 6.8 15.7 27.3 18.4 0.0 14.5 726.6 1.0 0.0 1.9 3.0 1.0 0.9 38.6 1.8 79.3 0.1 1.0 18.8 18.3 1.1 1.0 705.6 0.5 41.0 13.6 2318.6 0.0 0.2 0.5 0.0 1950.8 1526.3 9.4 5.3 1971.3 80.0 12.2 808.9 0.2 1037.1 0.0 0.1 1.0 1.4 1.2 10.1 1.3 0.4 5.4 15.3 2.3 72.3 3.8 11.2 1.0 2.5 1.4 35.9 23.7 133.3 0.4 0.6 1.8 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 75.0;Hepatic stellate cells: 333.8;Langerhans cells: 244.0;Macrophages: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 24.9;HMC-1: 31.2;NB-4: 7.3;RPMI-8226: 11.7" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" 30.4 7.5 0.9 12.2 1.3 1.7 15.4 1.3 3.3 9.7 4.2 10.3 3.0 2.6 2.8 11.4 4.4 13.0 7.9 0.7 1.1 4.2 42.4 21.7 15.8 4.5 1.1 4.8 4.7 2.8 1.4 398.2 2.2 1.8 11.0 1.1 7.0 2.8 2.2 4.8 16.0 16.6 2.2 25.5 4.9 2.5 1.4 7.4 4.2 13.7 29.6 18.7 3.1 5.8 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 7.3 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.8 0.0 327.2 8.5 26.4 1.4 9.7 0.6 202.8 0.7 1.1 72.4 160.4 0.1 1.4 53.6 0.7 9.5 0.1 0.1 13.0 0.9 1.3 1.3 3.3 0.7 1.1 4.5 1.1 2.2 2.2 1.4 5.8 2.2 0.0 3.9 0.0 75.0 5.4 0.1 0.0 0.0 0.0 0.3 0.9 2.1 2.8 1.3 0.0 0.0 0.2 5.6 0.0 0.0 0.0 4.8 0.0 0.0 49.8 0.0 3.2 0.0 0.0 0.2 1.7 1.1 0.0 2.5 0.2 333.8 8.2 7.6 0.0 0.0 0.0 0.0 47.4 244.0 4.2 0.6 145.5 23.2 0.0 9.5 0.0 5.2 0.0 0.1 0.0 0.0 0.0 45.4 0.0 0.0 0.3 0.0 0.0 0.0 1.7 2.5 0.3 0.2 0.7 3.1 0.4 5.8 0.1 0.1 0.0 FCGRT "alpha-chain, FCRN" ENSG00000104870 "Fc fragment of IgG receptor and transporter" P55899 19 49506816-49526428 "Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1362.6;Kupffer cells: 877.7;Paneth cells: 883.9;Proximal enterocytes: 1787.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2346.7" "Group enriched" "Detected in all" 17 "dendritic cells: 922.9;granulocytes: 2346.7;monocytes: 1364.4" "Cell line enhanced" "Detected in many" "ASC diff: 153.7;Hep G2: 144.0;OE19: 165.4;THP-1: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Enhanced NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA012122: AB_1848474, HPA015130: AB_1848475" "unprognostic (2.19e-3)" "unprognostic (2.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (3.87e-3)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (2.00e-3)" "unprognostic (3.64e-1)" "unprognostic (3.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-3)" 263.1 127.7 67.7 99.6 73.3 147.3 198.8 68.0 102.5 217.2 111.1 209.6 304.4 143.1 48.8 60.2 155.5 144.6 123.0 66.3 75.1 177.6 401.6 177.5 143.3 74.0 69.5 193.2 129.4 114.5 79.8 137.5 74.3 104.6 149.3 4.8 106.2 94.7 64.4 112.3 299.3 91.6 73.6 318.9 126.6 28.3 78.8 62.9 111.9 77.8 39.1 136.7 132.0 78.2 0.4 37.1 4.3 123.7 153.7 78.2 6.0 32.1 73.4 20.9 22.9 50.5 22.5 0.2 59.4 45.9 10.8 8.5 1.2 1.1 11.7 0.3 45.5 74.2 0.6 144.0 95.8 1.1 14.2 95.1 1.9 17.5 0.2 86.5 81.3 48.0 12.2 10.9 53.7 0.8 0.6 14.3 2.1 165.4 22.0 2.6 35.3 3.7 96.0 9.3 2.6 23.1 5.6 0.2 4.5 18.3 26.5 196.1 28.1 52.8 11.8 0.9 1.3 2.4 13.5 9.8 10.8 70.2 7.9 566.8 1364.4 1011.5 24.7 904.8 29.8 58.0 39.8 39.7 922.9 62.5 89.4 51.0 2346.7 28.6 630.2 536.4 28.2 1276.9 67.7 73.3 68.0 102.5 66.3 75.1 74.0 69.5 74.3 73.6 78.8 78.2 479.6 67.3 89.3 21.2 44.2 126.1 130.4 130.7 52.9 0.7 125.5 151.3 30.7 158.7 79.9 73.5 4.2 12.7 83.8 652.3 60.7 86.3 6.5 29.1 89.6 259.2 158.1 55.8 0.2 61.6 24.9 269.9 108.6 24.8 70.5 181.2 587.6 343.9 1362.6 0.0 0.2 349.0 57.0 877.7 438.1 21.8 362.2 608.6 186.7 24.4 190.6 13.4 11.3 10.1 0.2 90.6 883.9 183.6 63.2 87.9 1787.7 329.5 53.4 5.2 216.9 149.2 105.6 21.1 17.6 27.7 107.1 20.7 32.4 129.9 565.1 115.4 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Group enriched" "Detected in some" 15 "Hofbauer cells: 56.5;Kupffer cells: 97.4;Langerhans cells: 223.6;Macrophages: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Group enriched" "Detected in some" 5 "HEL: 10.0;hTERT-RPE1: 2.7" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" 10.6 12.1 0.6 23.9 1.1 0.4 5.3 0.5 2.4 5.5 2.2 12.6 11.2 3.7 1.5 5.7 2.0 18.8 3.8 0.6 0.7 3.2 21.3 28.2 13.9 3.1 1.0 1.7 2.3 2.2 0.9 5.6 2.8 2.5 18.2 0.3 2.4 2.9 0.9 2.7 14.4 8.9 1.2 16.3 7.1 2.7 6.0 8.1 2.2 2.0 11.0 17.4 1.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.6 1.1 0.5 2.4 0.6 0.7 3.1 1.0 2.8 1.2 6.0 3.9 0.5 0.0 1.7 0.3 2.7 5.6 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.0 2.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 1.5 56.5 0.0 0.2 0.0 0.0 97.4 223.6 0.2 0.3 66.6 7.2 1.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.1 0.0 0.0 1.5 0.1 0.0 0.3 0.5 0.0 0.1 0.4 4.5 0.8 0.6 0.0 0.0 0.1 FTL "MGC71996, NBIA3" ENSG00000087086 "Ferritin light chain" P02792 19 48965309-48966879 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Iron storage" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 14422.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 74983.4;Kupffer cells: 70127.1;Macrophages: 34584.5;Proximal tubular cells: 58047.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 125209.0;monocytes: 102128.9" "Cell line enhanced" "Detected in all" "HHSteC: 24796.9;HSkMC: 20811.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020769, HPA041602" Enhanced Approved Cytosol NA NA 170000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB020769: , HPA041602: AB_2677575" "unprognostic (2.95e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-1)" "unprognostic (1.56e-3)" "unprognostic (7.48e-2)" "unprognostic (5.28e-2)" "unprognostic (2.16e-3)" "unprognostic (6.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" 6778.7 3262.2 6806.2 2353.2 7172.4 4213.8 4226.0 6782.1 10053.2 2094.3 6429.7 2451.1 2427.0 1523.4 1010.8 1306.2 2169.9 4298.0 2537.3 6497.7 6998.4 8845.6 14422.9 7261.1 3353.2 7250.8 6998.4 2455.3 2166.2 931.7 1730.4 3423.2 7218.5 1946.5 1800.0 684.9 1663.5 1390.4 1345.9 1449.7 2806.6 1842.3 7149.5 6751.4 3204.5 455.9 7581.8 1168.9 3000.4 1072.0 1334.6 4239.9 1804.7 7334.0 869.7 12906.5 949.6 1457.0 16013.9 16478.6 1693.1 2194.1 12820.0 3090.7 6903.8 2852.3 3413.2 656.4 4104.3 13203.9 6755.6 505.8 788.2 1301.8 2765.6 8895.0 507.6 1740.0 3222.8 18949.7 24796.9 4133.3 5591.2 20811.1 1735.9 5272.5 2301.6 4590.4 4549.8 774.6 3284.9 1328.2 6198.4 213.0 1152.1 2402.8 1729.8 15140.6 1306.9 947.6 643.0 6763.9 1989.7 545.0 1209.9 701.5 5761.7 313.4 1239.5 5104.1 183.2 8493.4 3438.3 3353.4 1740.1 4364.3 3083.1 5690.2 13742.1 625.1 3563.9 4334.7 6017.7 64938.4 71067.8 77353.0 6560.6 102128.9 7527.7 17097.3 7247.4 7054.3 25176.6 15607.2 8656.4 7466.9 125209.0 4978.3 91398.0 10579.6 9634.4 94147.5 6806.2 7172.4 6782.1 10053.2 6497.7 6998.4 7250.8 6998.4 7218.5 7149.5 7581.8 7334.0 2757.2 1125.0 3379.9 88.5 3311.5 2793.9 6799.5 2785.4 2159.8 474.7 2597.9 3977.3 777.8 4398.0 2550.4 2021.2 177.2 941.5 2199.4 2314.2 10704.0 4251.2 290.2 504.9 1413.1 4867.0 1613.4 4331.2 60.6 6134.8 1447.8 5703.3 1715.1 617.4 2365.7 942.2 4598.0 23702.0 74983.4 533.3 113.8 2368.8 3039.4 70127.1 16939.0 1601.8 4175.9 34584.5 5085.3 129.3 22965.8 3161.9 2020.6 55.8 309.7 6905.5 5604.7 2010.8 4884.7 9790.5 21474.5 58047.8 1908.0 682.6 1341.1 1643.8 3455.6 82.1 311.2 1985.5 2226.7 1502.7 2590.4 1492.0 2816.8 13083.6 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 GAA ENSG00000171298 "Glucosidase alpha, acid" P10253 17 80101556-80119881 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 156.2;Extravillous trophoblasts: 143.9;Kupffer cells: 122.7;Syncytiotrophoblasts: 166.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 66.6;eosinophil: 22.8;intermediate monocyte: 50.3;myeloid DC: 39.7;neutrophil: 27.0;non-classical monocyte: 68.5" "Group enriched" "Detected in all" 10 "dendritic cells: 39.7;granulocytes: 27.0;monocytes: 68.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced Approved Vesicles NA NA 3800000 "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA026970: AB_2672065, HPA029126: AB_2672918" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (2.94e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (7.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (1.18e-1)" 31.7 29.9 16.9 22.6 20.8 16.7 30.1 19.2 26.5 25.8 17.1 29.2 24.7 31.2 35.2 15.8 29.1 29.9 35.1 18.3 24.7 37.6 47.3 44.4 22.5 28.2 21.6 18.8 37.2 33.3 38.8 48.5 26.6 33.2 8.7 6.6 37.7 23.6 47.0 25.5 26.9 14.6 21.0 54.3 26.9 56.0 26.0 20.4 32.6 25.1 7.0 31.5 22.0 31.4 35.6 67.8 13.2 43.2 40.4 40.2 85.1 21.8 39.6 16.2 13.2 20.3 56.3 12.7 56.5 17.3 13.8 14.8 4.1 25.2 3.8 16.5 49.9 0.2 12.8 73.3 69.7 1.7 40.4 86.7 35.4 30.6 10.5 32.8 28.9 33.5 12.9 51.5 12.4 81.3 6.0 8.4 27.3 8.7 46.8 30.9 44.8 22.2 13.1 36.5 15.1 43.4 28.5 31.3 39.0 8.1 89.5 50.1 18.8 59.7 31.5 43.6 8.1 121.4 36.5 3.8 19.1 32.8 38.4 0.6 66.6 22.8 3.7 50.3 4.4 3.1 2.8 3.8 39.7 3.0 3.2 2.3 27.0 3.0 68.5 9.5 2.1 32.9 16.9 20.8 19.2 26.5 18.3 24.7 28.2 21.6 26.6 21.0 26.0 31.4 21.9 19.2 41.3 31.6 9.3 11.2 19.6 38.7 8.0 16.1 24.1 28.2 19.9 24.3 24.7 14.7 8.4 156.2 11.8 11.5 5.9 25.2 55.7 14.3 16.7 21.6 6.1 4.8 16.2 15.8 143.9 33.0 20.4 27.8 8.8 28.5 23.6 26.4 99.8 11.8 18.9 10.9 12.2 122.7 29.6 29.3 23.9 83.9 24.9 20.6 39.1 32.1 8.2 11.6 12.5 9.4 13.5 19.2 12.9 20.2 31.4 21.5 9.3 18.5 6.6 15.0 13.9 66.0 29.4 10.3 8.4 166.2 8.2 30.2 14.4 14.8 GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.2;Microglial cells: 23.4;Oligodendrocyte precursor cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cell line enhanced" "Detected in many" "WM-115: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" 4.3 4.9 9.2 3.9 9.3 0.7 3.7 8.4 12.6 11.0 7.6 6.1 3.8 9.1 3.1 7.8 6.0 5.6 5.0 9.1 9.5 1.4 0.9 5.2 2.9 13.4 9.5 6.3 1.4 3.0 4.2 5.1 10.1 4.8 6.3 0.5 25.6 3.6 1.9 27.7 5.0 9.9 10.7 2.7 2.4 4.8 15.9 22.3 1.9 1.9 3.2 6.7 10.6 13.1 0.1 0.9 5.4 2.3 4.7 9.6 10.9 3.2 3.2 1.8 2.6 0.6 0.2 1.1 0.7 10.4 3.3 12.2 0.3 1.8 0.6 0.1 0.6 0.4 0.2 0.4 3.4 0.3 2.7 11.7 4.6 5.5 0.6 4.0 3.7 4.3 1.6 0.2 3.4 0.4 4.2 0.2 1.9 11.5 1.3 2.7 2.4 0.2 0.0 0.4 0.3 2.2 1.0 0.0 6.7 1.0 0.0 0.3 3.4 0.3 1.6 0.5 0.1 0.2 0.2 2.5 1.9 0.4 43.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 4.5 0.3 0.0 0.1 15.0 4.6 0.3 0.2 0.1 4.7 1.3 2.2 9.2 9.3 8.4 12.6 9.1 9.5 13.4 9.5 10.1 10.7 15.9 13.1 0.7 0.0 0.5 2.9 0.1 4.2 2.0 3.3 7.4 0.0 2.2 2.4 1.0 1.5 0.9 0.0 0.0 0.3 0.3 1.5 0.0 0.6 0.2 0.2 2.1 1.2 0.0 2.7 0.5 0.0 0.4 7.5 0.0 0.3 0.0 1.2 1.4 0.0 37.2 0.0 0.3 1.3 4.1 1.3 0.8 0.0 4.7 9.6 5.4 23.4 0.7 0.4 0.0 24.6 0.5 0.3 2.5 5.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 3.7 3.3 0.6 0.3 4.2 8.1 0.8 0.7 0.1 4.1 1.4 GAS2L3 ENSG00000139354 "Growth arrest specific 2 like 3" Q86XJ1 12 100573683-100628288 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 4 "spinal cord: 13.8" HPA048593 Approved NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA048593: AB_2680455" "unprognostic (1.03e-1)" "unprognostic (5.13e-2)" "unprognostic (5.10e-2)" "unprognostic (2.70e-2)" "unprognostic (2.32e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-7)" "unprognostic (2.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.58e-7)" "unprognostic (1.34e-1)" "unprognostic (2.35e-1)" "unprognostic (3.60e-2)" "unprognostic (6.67e-2)" 1.8 0.8 0.1 1.6 1.4 5.6 0.8 0.1 0.7 1.2 0.5 3.3 2.7 0.7 0.4 1.6 0.3 4.8 1.5 0.5 0.1 1.3 1.0 2.5 1.3 0.5 0.5 1.1 0.5 0.2 0.2 3.5 0.5 0.3 3.8 0.4 0.5 1.1 0.8 3.4 2.7 1.6 0.3 1.4 1.4 4.0 1.4 0.9 0.6 1.2 1.2 1.6 0.5 1.1 35.4 14.0 18.6 14.8 5.7 7.3 6.2 16.2 15.3 21.3 23.8 10.4 9.5 0.6 4.8 12.8 20.8 11.8 12.0 5.9 31.0 10.0 9.1 0.0 12.2 7.0 1.9 0.0 8.0 2.9 0.6 12.8 36.1 10.1 20.2 0.0 2.2 0.0 17.7 10.4 0.0 0.2 5.9 6.5 16.7 2.4 32.5 0.8 9.2 9.6 8.4 8.1 17.0 11.7 22.2 6.5 21.3 1.9 13.6 13.6 14.3 12.2 17.8 7.4 9.3 0.0 5.3 5.6 39.3 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.1 0.1 1.4 0.1 0.7 0.5 0.1 0.5 0.5 0.5 0.3 1.4 1.1 3.6 0.0 0.0 1.0 0.2 3.4 0.4 0.5 2.8 0.2 2.0 2.2 2.0 11.5 0.2 0.0 0.0 9.9 0.4 9.8 0.0 2.7 4.5 3.6 5.5 5.6 3.6 6.9 2.5 0.7 4.5 2.2 11.2 7.4 1.3 7.2 2.5 1.4 13.9 0.0 5.9 14.2 0.0 8.0 11.1 0.5 0.6 14.7 7.2 4.7 1.5 2.2 0.0 2.5 0.3 0.3 8.2 0.7 0.3 0.6 2.6 3.4 1.0 0.1 0.0 4.8 2.7 16.0 2.3 4.7 3.7 33.9 1.0 6.8 8.3 0.6 GBGT1 "A3GALNT, FS, MGC44848, UDP-GalNAc" ENSG00000148288 "Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)" Q8N5D6 9 133152948-133163933 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Hofbauer cells: 21.3;Kupffer cells: 31.9;Macrophages: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 64.1;HMC-1: 57.1;HUVEC TERT2: 24.0;NB-4: 29.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051298 Approved "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA051298: AB_2681428" "unprognostic (4.63e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (2.70e-1)" "unprognostic (8.87e-2)" "unprognostic (4.38e-1)" "unprognostic (2.97e-2)" "unprognostic (7.43e-2)" "unprognostic (9.04e-2)" "unprognostic (2.27e-3)" "unprognostic (2.35e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (2.92e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-2)" "unprognostic (6.35e-2)" 9.9 10.5 6.3 11.0 5.9 9.9 6.5 11.8 7.0 5.4 11.8 5.3 3.3 6.7 2.7 3.6 7.4 7.5 6.7 5.9 8.2 5.6 1.3 9.7 9.7 13.5 11.2 12.5 3.4 4.8 4.2 12.8 13.8 6.1 3.2 1.0 4.8 4.2 2.2 3.5 6.7 6.7 7.7 8.9 22.2 1.3 11.5 2.7 6.7 2.9 8.1 6.0 6.3 8.5 0.1 1.6 1.5 0.0 1.0 1.1 0.5 4.7 3.8 2.6 0.1 0.0 0.9 1.2 15.5 4.7 1.7 17.3 10.5 1.0 0.1 0.0 0.5 64.1 1.1 0.0 12.4 2.4 57.1 5.3 1.7 0.6 0.1 10.5 24.0 0.8 18.7 0.2 1.0 0.3 0.2 29.0 4.9 0.5 0.4 4.5 0.4 1.7 1.6 0.2 0.4 1.8 0.0 2.6 0.1 2.0 0.1 14.0 14.8 0.0 2.0 1.9 0.1 0.0 0.0 0.1 0.3 10.2 0.8 6.2 10.7 5.2 0.2 7.2 0.4 1.8 0.3 0.0 3.0 2.7 0.1 0.1 1.7 0.2 6.4 2.2 0.2 2.5 6.3 5.9 11.8 7.0 5.9 8.2 13.5 11.2 13.8 7.7 11.5 8.5 1.6 0.0 1.7 4.9 4.9 0.8 2.2 0.6 2.8 0.3 4.1 2.7 2.6 1.5 0.7 1.8 0.0 2.4 0.0 0.6 0.0 3.2 0.0 0.5 1.8 1.8 0.0 16.4 2.4 0.6 1.1 7.3 2.6 0.3 11.4 3.6 0.7 0.0 21.3 0.0 1.9 0.3 0.0 31.9 3.1 0.0 7.5 22.0 0.0 5.6 11.1 2.4 0.0 1.5 0.0 0.8 12.1 1.9 0.7 1.5 0.1 1.6 0.0 0.2 0.0 3.9 6.2 0.1 0.1 1.4 1.1 3.6 2.0 0.5 1.2 1.7 GHDC LGP1 ENSG00000167925 "GH3 domain containing" Q8N2G8 17 42188799-42194532 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031650 Uncertain "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA031650: AB_10601014" "unprognostic (2.30e-2)" "unprognostic (1.63e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.21e-4)" "prognostic unfavorable (6.81e-5)" "unprognostic (5.13e-2)" "unprognostic (3.35e-2)" "unprognostic (2.56e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (6.69e-3)" "unprognostic (5.18e-2)" "prognostic favorable (2.00e-6)" "unprognostic (2.08e-1)" "unprognostic (7.93e-2)" "unprognostic (9.66e-2)" "unprognostic (4.02e-2)" 15.7 32.9 14.3 10.1 15.2 11.8 15.8 15.1 16.2 18.6 15.2 15.3 15.8 15.1 11.0 8.8 15.9 10.6 12.3 13.9 15.8 24.5 18.6 15.9 13.2 18.3 15.7 22.2 26.4 12.8 16.7 9.3 16.7 20.7 5.3 3.8 24.1 14.2 7.8 9.8 19.4 5.3 15.0 32.2 19.5 5.9 15.5 7.4 26.8 5.7 6.5 15.5 13.3 16.3 7.5 26.1 1.8 20.5 6.8 6.0 16.1 9.9 7.7 5.0 6.5 8.4 35.4 11.4 34.9 9.2 6.1 0.6 5.8 0.2 1.2 18.8 21.1 17.3 11.9 18.0 17.7 13.9 70.4 9.1 5.3 13.7 4.2 6.1 7.8 6.9 16.8 50.0 2.6 9.2 9.0 27.1 4.4 28.1 0.0 8.7 9.5 49.8 13.8 6.0 4.0 13.9 0.3 46.1 34.4 0.4 31.8 22.0 6.7 23.3 9.2 20.4 4.7 37.3 31.3 7.7 19.7 17.3 9.6 0.8 3.2 1.8 2.3 3.0 1.0 2.5 1.5 2.3 2.7 4.1 1.5 1.8 1.6 1.1 4.1 2.4 1.4 2.6 14.3 15.2 15.1 16.2 13.9 15.8 18.3 15.7 16.7 15.0 15.5 16.3 16.2 0.0 9.6 4.9 9.9 2.9 9.3 8.8 2.2 7.6 8.8 7.1 2.1 14.3 6.7 16.5 6.2 13.1 8.7 5.1 3.9 12.9 1.0 5.6 8.5 12.6 13.8 4.6 2.6 19.3 11.6 10.0 6.1 8.9 13.3 6.5 28.5 15.3 27.9 8.4 4.3 10.7 8.2 25.5 5.4 1.3 11.5 12.6 8.8 2.8 9.3 16.2 13.4 1.0 3.5 10.3 4.8 13.9 4.7 6.5 25.6 16.5 7.8 5.5 0.0 12.8 6.3 2.8 0.5 2.2 1.8 7.3 9.5 15.9 9.4 5.4 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GLIPR1 "GliPR, RTVP1" ENSG00000139278 "GLI pathogenesis related 1" P48060 12 75480753-75503863 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 216.3;Extravillous trophoblasts: 384.2;Hofbauer cells: 242.4;Kupffer cells: 273.9;Langerhans cells: 393.2;Macrophages: 259.6;monocytes: 220.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 189.3;U-138 MG: 363.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011014 Approved "Intracellular and membrane" NA NA 64000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA011014: AB_1849714" "unprognostic (2.32e-3)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (3.31e-1)" "unprognostic (2.32e-3)" "unprognostic (4.09e-1)" "unprognostic (7.58e-2)" "unprognostic (3.10e-1)" "unprognostic (7.23e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.69e-9)" "unprognostic (9.06e-3)" "unprognostic (5.08e-2)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" 17.2 16.9 2.0 47.0 1.7 18.3 11.5 1.5 5.6 15.6 3.8 11.4 6.6 32.6 6.0 7.9 17.9 33.5 9.2 2.3 2.8 5.6 12.5 22.1 32.7 4.0 3.3 13.7 3.7 2.3 3.9 25.8 3.9 9.2 12.6 1.7 9.7 17.1 3.1 3.4 14.1 39.9 3.4 36.4 10.8 4.8 4.2 19.8 5.4 7.3 32.3 35.0 6.7 8.4 7.2 7.0 5.9 0.6 22.0 46.2 0.9 93.0 97.5 76.8 55.7 3.8 2.7 23.9 19.1 101.7 67.6 1.2 0.2 38.6 124.7 38.0 1.6 1.2 8.4 6.1 25.1 8.4 1.3 43.0 14.1 189.3 41.4 123.1 62.0 1.7 1.7 29.0 144.7 0.1 4.0 20.2 0.6 0.2 2.8 1.0 4.5 0.8 8.1 1.6 0.2 0.2 38.5 0.3 0.2 12.5 0.9 6.7 102.6 363.8 35.4 39.2 144.1 5.1 0.8 2.1 144.4 9.9 5.6 25.3 352.7 40.9 115.0 232.6 77.2 73.9 80.5 90.7 240.2 90.2 24.3 50.4 462.1 20.4 265.6 202.1 91.2 265.0 2.0 1.7 1.5 5.6 2.3 2.8 4.0 3.3 3.9 3.4 4.2 8.4 6.5 12.8 16.0 2.0 121.6 13.6 189.2 23.0 4.0 2.9 15.5 19.9 0.9 5.7 10.0 3.7 4.2 4.8 216.3 0.3 0.0 102.8 14.3 11.3 119.4 7.0 3.5 11.8 13.3 83.9 384.2 46.1 2.0 16.4 10.1 0.8 10.4 4.4 242.4 6.7 14.6 0.4 4.1 273.9 393.2 5.9 14.3 259.6 16.0 28.1 220.9 1.4 123.6 2.5 1.5 90.9 2.5 53.8 66.8 106.5 0.1 1.5 10.6 3.2 13.1 8.1 50.2 7.9 1.0 4.6 9.8 16.8 161.9 26.7 0.6 42.8 GLIPR2 "C9orf19, GAPR-1" ENSG00000122694 "GLI pathogenesis related 2" Q9H4G4 9 36136536-36163913 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 188.5;Langerhans cells: 203.6;Macrophages: 117.6;monocytes: 203.0;NK-cells: 180.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 71.6;HDLM-2: 72.9;TIME: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029478 Approved Uncertain Vesicles,Microtubules NA NA 19000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Microtubules "HPA029478: AB_10670038" "unprognostic (1.57e-2)" "unprognostic (5.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-2)" "unprognostic (1.33e-2)" "unprognostic (9.90e-2)" "unprognostic (2.50e-1)" "unprognostic (1.84e-2)" "unprognostic (4.26e-2)" "unprognostic (3.21e-1)" "unprognostic (5.87e-2)" "prognostic unfavorable (6.54e-7)" "unprognostic (6.57e-3)" "unprognostic (4.94e-1)" "unprognostic (1.02e-1)" "unprognostic (2.43e-2)" 38.5 20.9 17.6 52.7 22.8 73.8 32.4 21.0 22.6 45.9 14.1 73.7 14.7 77.8 15.1 18.6 36.9 24.1 24.2 17.2 19.3 8.8 6.9 62.6 29.9 24.8 22.1 13.3 5.6 2.5 4.9 8.8 22.3 38.3 33.1 2.7 15.3 39.3 7.7 12.2 32.2 63.8 22.8 41.3 25.3 3.4 26.7 18.7 15.8 11.1 19.2 38.8 27.4 27.6 3.7 2.9 20.9 22.3 71.6 33.3 2.4 32.9 20.0 7.8 14.1 1.3 0.3 0.2 10.2 30.9 19.7 0.2 7.9 1.1 4.7 72.9 6.4 8.8 6.2 0.4 27.9 5.7 28.3 23.4 1.0 44.5 7.8 14.0 62.5 22.6 0.4 5.0 17.4 7.9 27.9 15.2 20.1 0.3 10.7 18.9 44.1 1.0 1.6 1.8 5.6 11.3 4.4 2.2 3.6 42.2 2.3 24.0 127.3 10.7 24.8 9.6 28.0 7.8 2.2 12.7 11.0 35.0 2.5 268.6 360.9 540.3 168.4 162.5 89.1 24.4 114.3 108.2 208.3 24.5 47.0 74.7 657.0 125.5 124.9 18.5 132.2 414.0 17.6 22.8 21.0 22.6 17.2 19.3 24.8 22.1 22.3 22.8 26.7 27.6 11.9 3.2 25.4 4.6 22.3 13.4 2.5 14.7 1.8 0.3 46.9 19.0 2.6 2.8 30.9 5.5 0.0 3.8 66.9 14.7 0.0 21.2 0.7 1.8 33.9 13.3 8.4 58.7 1.1 1.3 3.3 54.3 11.7 2.1 52.6 1.9 16.1 0.9 188.5 0.0 0.8 42.4 14.2 83.2 203.6 2.3 18.0 117.6 62.2 2.8 203.0 21.4 180.2 3.0 28.6 5.2 16.1 25.9 22.8 16.0 4.0 1.1 64.3 0.5 46.0 44.7 43.2 0.9 6.4 0.9 10.2 3.4 75.5 10.9 45.3 3.3 GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA029121: AB_10600794" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (5.68e-2)" "unprognostic (4.22e-3)" "unprognostic (3.71e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.35e-5)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (9.21e-3)" "unprognostic (1.33e-1)" "unprognostic (7.66e-3)" "unprognostic (7.68e-3)" "unprognostic (3.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" 33.9 68.3 11.8 17.1 12.8 19.4 25.6 12.9 15.4 38.1 21.1 24.6 30.3 24.4 23.2 29.8 21.1 44.7 18.1 11.7 13.9 52.2 59.8 28.9 22.6 13.6 13.6 22.0 27.0 29.4 19.7 48.0 15.0 57.3 21.1 2.7 35.2 20.4 7.4 29.2 26.9 24.5 12.4 32.3 28.8 6.4 16.0 12.2 23.6 9.6 15.4 36.0 26.8 14.4 22.7 40.8 3.9 27.0 224.8 121.7 27.5 40.8 172.0 58.1 79.0 50.9 68.7 0.0 83.2 59.0 1.9 14.6 0.6 30.0 18.4 4.6 41.8 7.0 22.9 60.6 101.4 19.7 58.1 119.9 36.0 55.9 17.9 85.1 89.0 17.6 32.8 3.1 34.6 28.5 10.1 0.1 46.5 56.9 20.9 17.4 0.0 74.3 53.7 24.5 12.9 42.2 27.1 76.4 120.6 45.6 38.3 54.2 45.7 25.7 5.0 46.2 26.9 24.9 45.9 11.3 44.0 15.7 36.3 35.0 71.3 12.2 23.4 74.5 21.7 13.1 23.0 20.5 31.8 7.7 22.7 21.7 19.4 18.0 55.6 21.3 43.4 36.9 11.8 12.8 12.9 15.4 11.7 13.9 13.6 13.6 15.0 12.4 16.0 14.4 11.7 3.2 19.1 3.3 7.3 0.0 16.4 0.0 10.8 2.0 12.3 11.6 5.8 31.5 5.0 31.3 0.0 70.3 7.6 13.8 27.4 51.3 0.6 8.5 19.1 17.5 10.9 18.5 1.6 38.3 68.5 33.4 18.8 14.2 8.8 14.9 42.8 69.8 197.7 1.7 1.9 19.4 0.0 66.8 0.0 1.4 16.4 41.1 0.0 1.0 29.8 21.0 13.4 2.0 3.9 29.8 22.2 13.9 23.0 28.9 44.9 67.3 5.8 1.5 13.1 11.9 17.1 0.9 1.9 17.8 0.0 69.6 9.3 17.6 11.8 18.7 GNB4 ENSG00000114450 "G protein subunit beta 4" Q9HAV0 3 179396088-179451476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 81.1;Kupffer cells: 98.1;Macrophages: 66.8;Microglial cells: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018383, CAB018737, HPA040736" Supported Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB018383: AB_631542, CAB018737: AB_640712, HPA040736: AB_2677106" "unprognostic (2.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (5.97e-3)" "unprognostic (2.12e-1)" "unprognostic (1.44e-2)" "unprognostic (8.28e-2)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (1.90e-3)" "unprognostic (3.13e-2)" "unprognostic (8.90e-2)" "unprognostic (2.80e-3)" 14.9 6.3 8.7 21.9 19.2 33.7 12.4 7.3 11.2 11.5 2.9 9.5 5.9 9.2 3.7 21.9 7.0 15.2 13.9 9.6 8.7 5.9 7.8 16.0 17.7 15.5 8.5 5.8 2.8 2.7 3.0 21.8 14.5 4.5 8.6 2.0 4.7 4.0 3.1 34.1 6.4 23.5 14.5 18.1 7.4 4.3 10.9 7.9 6.3 5.7 11.5 13.2 6.8 19.7 33.4 15.4 37.7 0.8 23.8 41.5 44.1 46.7 33.1 54.1 61.3 0.8 3.7 61.6 9.9 54.3 49.7 0.6 36.4 43.1 56.7 143.6 29.2 71.3 54.9 0.7 23.4 62.3 16.2 32.9 6.6 42.4 21.6 12.0 59.3 13.7 18.7 0.8 42.8 1.3 32.8 24.3 18.9 0.2 19.3 61.4 49.2 25.3 34.9 1.9 7.0 20.5 37.5 33.0 61.1 23.0 67.5 26.1 45.3 45.1 27.4 13.6 61.6 0.3 0.9 0.8 24.7 52.8 35.4 5.6 21.3 11.0 0.2 27.8 0.1 6.7 0.4 0.3 24.9 13.6 0.4 0.3 14.5 3.4 23.5 12.8 0.6 8.8 8.7 19.2 7.3 11.2 9.6 8.7 15.5 8.5 14.5 14.5 10.9 19.7 40.0 25.6 12.8 17.9 20.1 18.7 1.8 2.5 13.6 1.7 14.3 12.3 15.6 0.0 12.3 3.7 6.2 13.8 11.5 0.1 3.9 1.1 1.2 15.6 22.9 42.9 0.0 22.9 18.6 1.6 18.7 26.6 3.6 10.8 10.8 16.2 53.2 0.9 81.1 1.7 18.4 0.0 2.0 98.1 17.4 1.4 10.2 66.8 14.2 91.8 59.9 0.8 2.1 11.6 7.7 2.8 0.0 15.8 8.1 2.6 0.2 0.2 11.3 4.0 26.3 9.9 41.8 2.3 16.8 23.4 25.4 4.1 2.9 14.7 0.0 1.3 GNPDA1 "GNPDA, GNPI, GPI, HLN, KIAA0060" ENSG00000113552 "Glucosamine-6-phosphate deaminase 1" P46926 5 141991749-142013041 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 127.2;Proximal tubular cells: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 382.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 930000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: AB_2679857" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (6.79e-2)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (8.89e-3)" "prognostic unfavorable (2.60e-6)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.09e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (9.66e-2)" "unprognostic (2.05e-3)" 18.8 38.4 26.9 17.3 28.8 8.1 20.9 26.2 35.2 26.7 27.7 19.7 29.5 28.7 51.9 13.6 18.4 22.3 17.3 28.1 30.8 76.4 16.6 17.6 22.7 27.0 27.7 31.8 11.3 27.9 20.5 22.2 29.3 22.2 21.9 17.7 14.6 28.3 26.4 14.8 22.5 29.2 27.0 30.9 14.5 18.8 29.7 24.9 27.8 25.7 19.8 33.3 17.1 30.7 42.6 61.0 23.2 115.8 77.1 51.9 54.6 32.6 78.7 84.7 95.8 91.3 49.2 0.2 72.9 23.6 382.3 44.0 109.9 98.0 74.8 32.9 46.5 31.3 33.1 65.5 137.2 86.4 39.2 63.5 56.9 54.5 144.8 63.2 91.6 80.6 37.3 110.1 93.0 27.2 66.8 9.8 88.0 62.8 121.4 25.5 76.3 94.3 81.8 114.8 20.6 54.0 65.0 67.8 127.9 67.5 54.6 26.5 43.3 50.9 33.3 76.9 47.5 61.2 126.9 47.1 74.2 29.3 45.0 0.3 48.6 7.1 37.2 59.1 77.9 19.4 30.0 34.2 51.7 11.1 35.3 38.8 12.7 15.8 56.3 29.6 27.6 40.2 26.9 28.8 26.2 35.2 28.1 30.8 27.0 27.7 29.3 27.0 29.7 30.7 10.5 9.6 14.9 10.7 8.2 6.0 40.8 20.9 21.1 11.6 12.6 17.8 12.6 12.8 20.1 18.4 8.4 26.7 11.1 6.9 35.2 29.3 1.1 5.8 19.8 14.6 15.0 9.9 11.5 14.2 48.6 22.8 7.7 9.6 12.0 30.8 15.4 7.4 127.2 6.7 12.7 6.2 12.2 60.2 10.7 3.6 19.9 48.5 14.2 12.2 23.5 40.5 15.5 7.1 11.5 21.6 7.1 26.7 7.8 32.9 19.4 102.3 8.0 7.9 0.0 10.4 11.7 10.4 17.0 17.6 7.4 29.7 16.6 64.8 9.1 34.7 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 GPR84 EX33 ENSG00000139572 "G protein-coupled receptor 84" Q9NQS5 12 54362445-54364487 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.8;urinary bladder: 15.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 21.9;Langerhans cells: 17.7;Macrophages: 31.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "basophil: 9.0;classical monocyte: 9.9;myeloid DC: 14.8;neutrophil: 6.0" "Group enriched" "Detected in many" 62 "dendritic cells: 14.8;granulocytes: 9.0;monocytes: 9.9" "Group enriched" "Detected in some" 5 "HL-60: 13.0;NB-4: 40.0" HPA027603 Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA027603: AB_10612115" "unprognostic (5.40e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (2.36e-2)" "unprognostic (4.54e-2)" "unprognostic (6.16e-3)" "unprognostic (7.43e-2)" "unprognostic (9.29e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-2)" "unprognostic (2.92e-1)" "unprognostic (1.36e-9)" "unprognostic (1.27e-1)" "unprognostic (4.42e-2)" "unprognostic (1.40e-1)" "unprognostic (9.44e-2)" 4.5 1.1 1.0 8.3 1.1 22.8 0.3 1.0 1.8 0.4 1.4 0.4 0.3 0.3 0.3 0.5 0.7 1.0 0.6 1.0 1.7 0.9 0.4 2.4 0.3 2.6 1.6 0.3 0.4 0.1 0.8 3.1 1.7 0.6 0.6 2.7 0.6 0.2 0.0 0.7 0.4 1.9 1.7 3.6 0.6 0.3 1.8 0.5 0.6 0.2 0.8 15.8 0.4 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.0 2.2 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 5.1 0.0 9.0 9.9 0.0 0.0 0.4 0.0 0.0 0.0 0.1 14.8 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 2.1 1.0 1.1 1.0 1.8 1.0 1.7 2.6 1.6 1.7 1.7 1.8 3.1 0.2 0.0 0.5 2.0 0.3 0.9 0.1 4.6 0.0 2.6 0.2 0.3 0.1 0.0 1.2 0.0 4.2 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 1.6 0.0 0.0 0.8 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 1.1 0.0 0.0 2.8 17.7 0.2 0.0 31.8 0.0 0.0 1.2 0.1 0.0 1.5 0.8 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 0.1 0.4 0.8 0.1 0.0 0.0 0.1 GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1420.7;Kupffer cells: 892.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9" "Group enriched" "Detected in all" 9 "dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" NA NA 138000000 110000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" 158.9 123.2 61.5 160.4 67.2 478.5 120.7 67.7 97.3 156.7 73.9 189.8 130.9 108.3 134.0 534.0 87.1 157.3 153.0 61.0 69.7 167.4 118.9 309.5 183.2 81.0 71.5 73.8 108.9 87.8 84.4 183.2 87.6 111.7 110.3 12.5 262.9 100.6 60.6 189.7 179.0 91.9 71.8 349.8 127.9 59.4 94.3 67.8 127.7 45.9 107.8 150.0 198.3 97.3 119.3 197.5 52.7 159.5 443.2 231.8 181.2 147.3 447.5 231.6 309.8 86.3 294.0 364.0 299.4 217.6 312.9 185.3 68.6 334.5 75.8 55.8 186.8 38.4 93.8 175.2 245.5 61.6 493.6 332.4 450.5 188.1 106.0 391.2 269.8 64.3 75.1 51.3 148.8 183.1 32.8 172.8 44.3 110.5 334.0 97.7 180.8 433.0 248.2 145.9 54.7 74.7 201.0 92.7 360.9 138.0 209.4 229.0 340.7 437.6 104.6 300.5 97.8 116.3 313.9 122.3 268.1 149.6 124.2 215.1 2057.5 176.5 35.1 1122.4 27.8 174.0 37.1 31.1 1534.2 112.2 27.8 26.5 851.2 30.6 548.1 1331.9 55.4 1613.4 61.5 67.2 67.7 97.3 61.0 69.7 81.0 71.5 87.6 71.8 94.3 97.3 113.0 86.6 83.3 12.7 82.8 112.7 151.1 574.2 97.9 23.6 85.7 69.7 90.7 133.0 332.7 218.8 18.8 429.1 195.7 494.8 9.8 447.7 2.1 103.8 83.8 170.9 124.3 38.7 6.8 307.3 324.1 149.4 83.6 372.5 75.5 90.0 207.8 84.7 1420.7 47.1 6.6 214.6 146.5 892.0 360.8 6.8 60.9 699.2 208.1 20.6 501.6 58.9 20.6 11.1 11.8 285.3 581.7 57.2 65.8 70.7 312.1 120.5 70.0 11.8 85.5 45.4 83.3 25.1 72.2 255.5 96.5 640.0 30.8 89.6 274.5 175.6 GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.7;Hofbauer cells: 5.0;Kupffer cells: 5.6;Macrophages: 2.6;Suprabasal keratinocytes: 2.7;Theca cells: 2.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HBEC3-KT: 4.1;hTCEpi: 2.7;hTERT-HME1: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" 3.4 0.7 0.2 0.9 0.2 0.4 3.5 0.4 0.4 0.8 0.2 0.7 0.6 0.4 6.6 3.2 0.3 0.8 0.3 0.3 0.2 0.3 0.3 0.4 0.7 0.4 0.0 0.1 0.3 1.3 0.1 1.6 0.4 0.1 1.2 0.0 0.8 0.0 0.4 58.9 0.5 0.6 0.0 0.2 0.3 0.3 0.4 0.5 0.1 0.1 3.4 1.1 1.5 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.5 0.4 0.2 0.0 0.1 0.8 0.0 2.7 0.5 5.4 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.9 0.1 0.1 2.2 0.0 2.6 0.0 1.3 0.8 0.1 0.1 0.6 0.9 0.7 0.1 0.1 0.2 0.5 0.5 0.2 0.2 0.4 0.4 0.3 0.2 0.4 0.0 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 5.0 0.0 0.1 0.7 0.0 5.6 0.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 0.2 2.8 0.0 0.0 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 213.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 28.4 18.2 11.0 22.3 12.3 84.2 80.9 12.0 16.1 26.7 14.3 38.2 36.1 26.2 41.8 16.4 24.6 27.6 19.6 10.7 11.5 25.1 104.0 35.7 25.6 13.2 12.2 19.9 33.6 30.3 12.6 48.2 13.2 20.2 41.9 9.7 32.9 21.2 10.9 18.8 29.8 19.1 11.9 34.0 38.1 19.5 13.0 22.7 27.7 14.4 24.0 27.3 15.4 13.5 67.0 26.5 25.2 56.3 80.9 49.1 35.3 21.3 56.8 45.0 42.1 37.0 67.8 30.9 32.3 26.8 24.1 27.5 16.5 25.1 26.8 27.3 34.1 41.5 40.9 27.3 39.7 89.6 67.1 33.4 26.7 26.3 33.3 54.5 39.3 18.0 63.2 213.5 30.5 50.3 34.2 92.0 17.9 103.0 21.0 34.4 55.9 172.4 29.4 42.8 36.2 32.7 55.6 129.1 72.3 29.9 71.1 88.8 28.5 55.3 49.3 21.8 53.6 119.6 151.9 50.0 41.0 116.3 68.3 26.0 80.1 65.7 32.0 103.0 28.4 27.7 24.7 28.4 80.5 22.6 16.8 19.5 13.2 46.6 93.5 34.2 34.5 51.4 11.0 12.3 12.0 16.1 10.7 11.5 13.2 12.2 13.2 11.9 13.0 13.5 53.1 51.3 58.7 10.1 33.0 18.0 32.0 51.9 29.0 12.2 26.1 19.9 12.2 48.6 48.9 29.5 8.4 81.9 32.6 52.2 5.9 41.1 59.1 28.9 26.5 39.7 43.0 47.1 12.3 30.3 61.2 49.5 49.5 49.4 36.8 38.3 37.9 72.7 126.4 16.8 10.6 51.6 30.5 88.1 33.2 46.7 43.2 78.0 39.2 14.0 44.8 28.0 20.6 8.5 14.2 29.4 49.5 28.6 87.5 25.3 50.6 26.8 43.2 20.1 26.3 27.1 26.0 49.6 31.0 16.0 14.8 66.9 32.2 24.4 44.3 29.6 HBE1 HBE ENSG00000213931 "Hemoglobin subunit epsilon 1" P02100 11 5268345-5505652 "Plasma proteins, Predicted intracellular proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 174.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "K-562: 10059.8" "Not detected" "Not detected" HPA043234 Approved NA NA 510000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA043234: AB_2678378" "unprognostic (7.59e-2)" "unprognostic (6.70e-2)" "unprognostic (3.76e-2)" "unprognostic (4.25e-1)" "unprognostic (1.64e-1)" "unprognostic (9.03e-2)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (7.32e-2)" "unprognostic (1.02e-3)" "unprognostic (2.14e-1)" "unprognostic (5.80e-2)" "unprognostic (7.34e-2)" 0.5 0.3 0.4 0.0 0.7 0.3 0.2 0.0 1.1 0.5 0.0 0.2 0.0 0.3 0.4 0.1 0.4 0.0 0.3 0.5 0.8 0.3 1.3 0.3 0.0 0.7 0.2 0.6 0.2 0.0 0.3 0.8 0.5 0.4 0.0 0.2 0.1 0.1 0.4 0.2 0.2 0.2 0.0 0.4 0.2 0.5 0.4 0.2 0.3 0.0 0.0 0.2 0.3 1.1 1.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 649.4 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10059.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.4 0.7 0.7 0.0 0.0 31.9 0.1 0.9 19.4 0.1 0.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.7 0.0 1.1 0.5 0.8 0.7 0.2 0.5 0.0 0.4 1.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.9 0.0 0.3 4.3 0.0 16.0 0.5 0.0 31.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 174.7 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.3 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.6 0.2 0.0 0.0 14.8 0.1 0.0 0.9 0.1 HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340924-72376420 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 234.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 20000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles Cytosol "HPA018082: , HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favorable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" 49.8 56.1 18.3 37.6 21.1 110.0 58.5 20.4 21.6 73.8 28.5 55.1 49.8 42.6 164.6 24.8 47.8 76.7 54.3 19.9 20.1 90.1 79.4 84.2 54.2 23.0 21.3 39.3 30.6 54.0 26.3 102.0 24.6 45.3 67.0 32.1 45.0 53.3 22.1 21.8 41.2 59.5 21.7 54.7 45.1 35.6 27.0 38.1 76.5 33.2 42.4 71.6 19.7 29.9 39.8 66.4 27.8 53.8 223.6 253.1 39.7 54.8 274.1 115.3 182.8 34.6 282.7 32.9 50.9 110.0 59.9 77.1 74.5 34.6 72.5 26.5 30.0 41.4 60.4 60.9 172.9 99.9 113.1 216.7 101.3 50.4 89.3 210.3 107.4 48.4 65.1 197.6 156.0 33.9 21.7 50.0 16.0 128.9 0.3 22.3 60.6 75.3 129.1 61.6 23.8 26.4 136.5 126.6 307.3 56.1 23.4 123.9 54.1 171.9 70.7 160.1 59.3 104.7 151.8 33.4 62.1 130.4 85.3 24.2 84.6 60.1 43.8 35.7 38.7 41.1 28.8 38.9 98.0 38.0 22.5 33.2 8.1 51.3 13.3 37.3 28.2 63.0 18.3 21.1 20.4 21.6 19.9 20.1 23.0 21.3 24.6 21.7 27.0 29.9 68.9 64.1 62.4 19.9 46.3 22.2 33.3 94.3 19.4 42.4 28.6 30.4 26.9 30.0 68.0 66.2 106.3 150.2 54.2 36.6 60.7 88.3 20.6 27.2 30.2 50.8 47.2 19.1 22.7 38.0 68.0 78.7 42.8 40.6 29.9 49.9 43.5 42.9 234.3 26.9 24.7 46.3 81.4 92.8 75.0 13.7 74.3 118.1 94.3 24.4 60.3 38.4 82.4 20.6 26.7 39.1 74.6 44.8 37.7 33.0 68.5 66.7 37.5 56.9 46.0 24.5 31.7 24.3 32.3 13.5 15.6 157.6 36.7 45.2 50.6 27.5 HFE "HFE1, HLA-H" ENSG00000010704 "Homeostatic iron regulator" Q30201 6 26087281-26098343 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 39.2;T-47d: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017276, HPA053470" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Nucleoplasm "HPA017276: AB_1850677, HPA053470: AB_2682163" "unprognostic (6.96e-2)" "unprognostic (7.87e-2)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (6.07e-3)" "unprognostic (7.58e-2)" "unprognostic (4.23e-1)" "unprognostic (1.77e-1)" "unprognostic (8.21e-3)" "unprognostic (1.78e-1)" "unprognostic (3.31e-3)" "unprognostic (1.82e-1)" "unprognostic (1.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.17e-1)" 9.6 7.9 1.3 5.3 2.1 0.6 7.8 1.4 1.9 6.7 9.3 5.8 5.9 4.9 12.4 4.8 4.5 8.1 3.7 1.5 1.5 6.7 15.4 7.5 3.6 2.4 1.7 7.3 6.3 15.4 1.2 6.1 2.2 6.8 6.9 1.3 6.9 9.6 2.3 2.8 5.0 6.0 1.7 8.6 8.3 1.7 1.9 1.7 9.9 3.0 3.1 7.4 3.2 2.8 17.2 39.2 0.7 18.6 27.3 21.1 0.1 12.2 28.5 15.1 23.6 3.3 34.3 1.8 32.4 20.2 22.9 10.7 0.0 14.2 19.1 4.6 0.2 0.5 8.1 2.6 5.6 0.0 0.7 21.6 4.0 16.7 1.4 13.2 10.4 0.0 0.7 0.4 13.0 7.2 0.1 0.2 0.9 8.1 0.0 2.3 0.0 0.3 12.5 11.5 0.1 0.1 7.3 0.0 10.2 0.3 54.0 1.9 8.2 10.6 1.1 10.7 10.6 0.2 0.4 0.2 15.9 0.2 23.5 1.3 10.7 0.0 1.5 10.4 1.2 3.3 1.6 2.1 4.7 1.3 0.4 1.0 1.9 0.2 9.2 0.3 0.3 3.8 1.3 2.1 1.4 1.9 1.5 1.5 2.4 1.7 2.2 1.7 1.9 2.8 3.9 3.2 5.1 1.0 1.7 1.7 2.6 3.7 6.2 1.0 3.7 2.2 3.2 2.8 6.7 5.5 2.1 1.7 0.5 3.8 0.0 4.1 0.1 1.8 2.3 3.4 1.8 2.7 0.1 3.4 0.8 4.6 8.2 1.5 2.5 3.0 6.8 12.2 11.1 0.0 0.1 4.0 4.1 25.4 7.6 0.2 3.7 7.4 0.0 2.8 3.8 2.9 2.1 0.0 3.3 2.4 0.9 6.0 0.3 2.6 2.9 2.7 5.9 1.7 0.0 5.7 2.4 0.2 1.1 3.4 3.4 1.8 1.0 2.8 3.3 1.9 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 299.3;Kupffer cells: 263.7;Proximal tubular cells: 268.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "classical monocyte: 110.9;intermediate monocyte: 89.8;myeloid DC: 68.3;non-classical monocyte: 52.2" "Group enriched" "Detected in many" 23 "dendritic cells: 68.3;monocytes: 110.9" "Cell line enhanced" "Detected in many" "Hep G2: 227.2;HSkMC: 87.9;RT4: 117.1;SuSa: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA 130000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" Centrosome "HPA035480: AB_2674645, HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favorable (4.68e-4)" 70.4 18.2 13.0 41.7 13.3 12.6 62.3 13.1 18.8 57.3 19.2 53.9 29.3 62.8 27.1 17.5 34.5 68.7 21.7 15.6 19.1 109.7 245.9 49.0 35.1 16.0 15.3 91.0 29.0 40.2 9.5 46.8 18.1 37.0 56.4 6.1 30.5 44.3 5.9 17.4 29.1 33.1 16.1 37.5 29.1 10.3 14.5 8.2 14.6 11.9 16.4 49.7 24.5 22.2 0.7 0.9 5.6 14.6 61.9 64.6 0.4 3.9 6.2 0.4 2.3 29.7 15.7 0.9 50.2 17.0 0.8 1.1 11.9 0.0 0.1 0.7 4.9 0.2 44.5 227.2 28.0 0.3 0.6 87.9 0.1 21.5 0.0 4.7 15.9 0.1 0.5 0.7 47.4 3.7 0.0 0.5 28.1 39.3 5.6 0.5 1.5 0.2 67.9 117.1 0.1 0.8 22.1 28.4 0.1 107.9 1.0 53.2 4.8 4.8 11.8 6.2 16.3 0.4 0.3 0.7 20.9 27.8 3.3 1.3 110.9 0.7 0.5 89.8 0.3 1.8 0.2 0.2 68.3 0.5 0.3 0.4 3.9 0.5 52.2 1.5 0.7 32.6 13.0 13.3 13.1 18.8 15.6 19.1 16.0 15.3 18.1 16.1 14.5 22.2 15.5 28.9 44.1 9.4 5.0 35.6 81.5 64.6 30.7 0.7 78.1 65.4 2.2 133.0 88.9 60.7 0.0 54.9 2.6 59.4 123.3 122.1 1.5 28.3 50.6 9.4 16.4 16.8 16.8 48.0 81.6 54.2 20.9 115.3 0.0 17.4 19.2 165.7 299.3 0.0 13.8 67.8 24.4 263.7 97.2 4.2 131.4 127.4 56.9 31.9 122.0 25.5 4.1 45.8 14.3 71.0 108.6 105.3 0.2 39.8 31.9 268.3 38.4 0.8 78.9 55.2 55.7 0.5 0.9 33.2 25.9 37.6 4.0 43.9 83.5 126.1 IBSP "BSP, BSP-II, SP-II" ENSG00000029559 "Integrin binding sialoprotein" P21815 4 87799554-87812435 "Cancer-related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;pituitary gland: 2.0" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 5.8" "Group enriched" "Detected in many" 4 "breast cancer: 3.8;glioma: 12.2" "Region enhanced" "Detected in single" "thalamus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-138 MG: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.53e-2)" "unprognostic (3.55e-2)" "unprognostic (1.49e-2)" "unprognostic (3.93e-1)" "unprognostic (3.75e-2)" "unprognostic (9.48e-3)" "unprognostic (1.03e-3)" "unprognostic (4.07e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-11)" "unprognostic (6.20e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-3)" "unprognostic (2.11e-1)" 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 2.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.5 0.7 0.7 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IGSF6 DORA ENSG00000140749 "Immunoglobulin superfamily member 6" O95976 16 21639550-21652608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.8" "Group enriched" "Detected in many" 13 "Hofbauer cells: 216.2;Kupffer cells: 246.9;Langerhans cells: 132.6;Macrophages: 327.1;monocytes: 179.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 1213.7" "Lineage enhanced" "Detected in all" "granulocytes: 1213.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041023, HPA041072" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA041023: AB_10794434, HPA041072: AB_10794262" "unprognostic (7.94e-2)" "prognostic favorable (4.92e-4)" "unprognostic (1.18e-2)" "prognostic favorable (1.54e-5)" "unprognostic (3.27e-1)" "unprognostic (4.03e-2)" "unprognostic (2.31e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-2)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (8.12e-2)" "unprognostic (1.81e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-1)" "unprognostic (2.02e-1)" 2.6 2.3 0.5 13.4 0.6 1.7 1.2 0.8 1.0 1.0 0.7 5.1 1.7 0.4 0.2 0.6 1.1 0.3 0.7 0.6 0.5 0.8 5.5 7.4 3.9 1.0 0.7 0.4 0.9 0.7 0.5 3.3 0.9 0.9 1.5 0.2 2.0 1.6 0.2 0.5 2.7 0.5 0.5 29.8 1.3 0.2 0.6 2.2 0.6 0.9 1.2 2.3 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.5 303.9 46.2 0.7 357.2 0.8 3.8 0.5 0.9 233.9 0.5 0.9 1.2 1213.7 2.7 263.5 55.5 1.0 210.7 0.5 0.6 0.8 1.0 0.6 0.5 1.0 0.7 0.9 0.5 0.6 1.4 1.7 3.2 12.2 0.7 7.1 3.2 0.7 0.0 0.0 1.3 1.4 3.7 4.0 2.8 5.0 1.8 10.4 0.7 15.2 0.0 0.0 0.2 0.4 1.0 1.2 4.0 0.0 6.5 1.1 0.0 1.4 3.2 0.0 2.5 10.1 0.4 2.9 1.8 216.2 0.0 0.8 0.3 0.0 246.9 132.6 0.1 0.9 327.1 8.8 16.9 179.9 0.7 3.1 1.0 0.4 0.0 1.2 0.0 1.3 0.6 0.1 0.4 4.4 2.1 0.0 0.9 1.1 0.1 0.2 0.6 2.0 1.4 5.4 0.2 0.0 0.5 ITGAD "ADB2, CD11d" ENSG00000156886 "Integrin subunit alpha D" Q13349 16 31393335-31426505 "CD markers, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 20.5" "Cell type enhanced" "Detected in some" "dendritic cells: 1.1;Kupffer cells: 4.2;Late spermatids: 1.0;Macrophages: 1.6;T-cells: 2.3" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026786 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026786: AB_10603773" "unprognostic (2.79e-2)" "unprognostic (2.39e-4)" "unprognostic (2.88e-2)" "unprognostic (3.24e-2)" "unprognostic (6.17e-2)" "unprognostic (1.79e-2)" "unprognostic (7.44e-4)" "unprognostic (6.99e-3)" "unprognostic (6.89e-3)" "unprognostic (5.02e-4)" "unprognostic (5.50e-2)" "unprognostic (1.67e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (3.17e-1)" "unprognostic (8.10e-2)" "unprognostic (5.51e-2)" 0.2 0.0 0.0 0.8 0.0 3.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.1 0.4 0.2 0.1 0.0 0.0 1.3 0.3 4.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 20.5 0.1 0.2 0.1 1.2 0.0 0.0 1.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.4 0.4 0.0 0.8 0.0 0.2 0.0 0.0 4.2 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSG00000120457 "Potassium inwardly rectifying channel subfamily J member 5" P48544 11 128891356-128921163 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 64.3;pancreas: 20.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 48.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "HBEC3-KT: 13.3" "Group enriched" "Detected in many" 6 "basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6" "Low region specificity" "Detected in all" "HPA014722, HPA017353, CAB022569" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "CAB022569: , HPA014722: AB_1852133, HPA017353: AB_1852135" "unprognostic (2.01e-1)" "unprognostic (2.43e-3)" "unprognostic (2.56e-3)" "unprognostic (5.81e-2)" "unprognostic (4.24e-2)" "unprognostic (3.60e-2)" "unprognostic (2.90e-1)" "unprognostic (3.54e-2)" "unprognostic (6.83e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.81e-2)" "unprognostic (6.82e-2)" "unprognostic (9.49e-2)" "unprognostic (1.88e-2)" "unprognostic (2.23e-2)" 1.5 64.3 1.2 0.6 0.9 0.4 0.9 0.6 2.0 1.3 0.2 0.8 0.8 0.3 0.9 1.0 0.9 2.2 8.5 0.7 3.2 5.4 0.4 5.9 1.6 3.7 1.7 0.9 20.4 1.3 11.9 7.3 2.7 1.3 0.7 1.0 0.9 9.6 0.4 0.4 0.5 0.6 1.7 13.6 2.3 1.1 7.9 5.8 0.5 0.4 0.5 1.5 0.4 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.3 13.3 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 1.2 0.9 0.6 2.0 0.7 3.2 3.7 1.7 2.7 1.7 7.9 3.9 0.2 0.0 10.0 0.3 0.2 1.5 2.2 4.7 0.0 2.7 0.2 1.4 7.6 0.0 0.3 1.8 0.0 0.8 0.1 0.0 0.0 0.1 2.3 0.2 0.2 0.6 0.0 0.0 0.2 3.9 0.7 1.1 0.0 0.3 0.0 0.2 0.4 0.1 48.3 1.7 3.1 0.0 0.0 2.2 2.9 7.8 0.9 10.9 3.6 3.7 1.2 0.3 3.1 0.5 0.1 0.8 0.0 0.7 0.3 0.6 0.0 0.1 0.3 1.4 0.0 0.9 0.2 0.9 0.5 0.5 1.7 1.2 0.6 2.3 0.0 0.6 KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 281.2;Endothelial cells: 192.2;Enteroendocrine cells: 386.7;Hofbauer cells: 218.9;Kupffer cells: 395.9;Macrophages: 221.3;monocytes: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cell line enhanced" "Detected in many" "ASC diff: 111.4;HUVEC TERT2: 229.0;TIME: 186.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" 76.1 27.8 21.4 55.7 20.1 12.0 52.4 27.0 20.8 44.5 12.4 39.5 22.5 51.3 17.8 38.3 75.0 55.0 22.6 26.9 27.8 31.0 13.9 58.0 39.4 36.2 33.5 47.1 12.5 25.2 6.4 83.9 31.4 14.7 42.5 3.4 20.0 18.5 16.6 22.9 28.1 65.3 37.0 64.8 28.0 26.9 31.4 18.3 16.4 37.1 33.4 39.2 17.4 34.4 1.7 1.5 15.3 0.0 111.4 52.5 4.3 6.9 1.5 4.2 5.5 0.5 0.3 0.0 3.8 18.8 4.9 53.9 6.6 66.4 3.5 1.5 35.1 0.2 38.3 0.0 4.7 18.6 0.1 21.4 21.5 2.7 48.9 8.5 229.0 13.2 0.3 0.2 53.9 1.4 8.5 0.3 7.8 16.6 7.7 0.4 7.4 19.6 17.7 0.2 4.3 7.9 17.3 0.5 2.2 18.5 1.0 12.1 186.0 2.7 4.9 0.4 14.0 2.7 0.5 0.0 42.5 4.0 16.1 0.0 3.9 0.7 0.0 2.5 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.0 0.0 1.5 1.9 0.0 0.9 21.4 20.1 27.0 20.8 26.9 27.8 36.2 33.5 31.4 37.0 31.4 34.4 281.2 25.6 8.4 2.9 7.5 40.0 2.7 11.9 28.5 4.4 11.2 27.3 21.8 4.3 16.3 97.5 14.6 3.0 30.4 19.7 17.6 6.5 3.6 4.9 44.6 192.2 386.7 6.1 4.8 0.6 90.6 80.0 12.2 3.3 7.0 53.1 61.1 2.5 218.9 0.0 11.5 71.5 12.2 395.9 75.4 11.8 157.2 221.3 51.6 45.9 206.7 4.8 7.2 0.5 0.9 0.5 15.7 44.8 7.6 4.5 0.7 7.5 72.8 1.5 26.3 153.2 32.2 1.9 7.0 16.9 34.4 4.2 5.5 24.0 46.6 1.9 LACC1 "C13orf31, FAMIN, FLJ38725" ENSG00000179630 "Laccase domain containing 1" Q8IV20 13 43879284-43893932 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.4" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.0;eosinophil: 3.1;intermediate monocyte: 5.2;myeloid DC: 2.7;non-classical monocyte: 8.0" "Group enriched" "Detected in many" 4 "dendritic cells: 2.7;granulocytes: 3.1;monocytes: 8.0" "Cell line enhanced" "Detected in many" "HMC-1: 37.1;TIME: 118.2" "Low region specificity" "Detected in all" "CAB034228, HPA040150, HPA044211" Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB034228: AB_1564163, HPA040150: AB_10963540, HPA044211: AB_10961258" "unprognostic (2.48e-1)" "unprognostic (3.27e-2)" "unprognostic (4.54e-2)" "unprognostic (3.31e-3)" "unprognostic (1.17e-2)" "unprognostic (3.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.43e-2)" "unprognostic (3.03e-3)" "unprognostic (1.78e-2)" "unprognostic (6.06e-3)" "unprognostic (2.02e-1)" "unprognostic (3.93e-2)" "unprognostic (3.30e-1)" "unprognostic (9.36e-3)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" 6.4 6.6 12.7 12.2 22.3 1.9 5.4 10.8 20.6 4.5 6.8 10.3 9.9 3.9 3.2 6.8 3.2 9.8 10.1 11.7 13.6 4.8 7.2 6.4 8.8 13.9 14.5 3.4 3.5 9.9 2.8 6.1 15.2 5.4 13.3 0.8 4.6 4.9 1.4 4.8 13.8 5.8 12.5 7.2 6.8 9.4 17.3 6.5 3.5 1.2 8.3 11.1 2.9 27.4 4.7 2.5 1.3 0.0 2.7 12.3 9.5 10.3 25.7 2.8 3.9 5.3 10.5 9.9 2.3 13.8 6.0 6.7 0.3 2.9 4.5 6.6 1.7 12.3 2.6 1.9 12.5 2.9 37.1 16.3 8.5 10.3 12.6 3.4 5.9 1.1 0.0 7.1 6.4 2.3 0.3 3.7 0.9 2.6 2.2 2.3 0.0 5.2 7.4 5.5 1.6 2.5 3.4 1.2 4.9 6.8 1.5 6.2 118.2 3.5 1.1 18.8 0.1 0.0 0.0 2.4 10.0 3.7 8.0 1.0 3.0 3.1 0.7 5.2 0.8 0.8 0.6 0.6 2.7 1.0 0.2 0.3 0.1 0.4 8.0 0.5 0.8 1.0 12.7 22.3 10.8 20.6 11.7 13.6 13.9 14.5 15.2 12.5 17.3 27.4 4.6 12.8 6.8 1.0 5.9 5.7 8.4 8.1 3.4 0.5 5.1 4.6 24.2 4.3 7.8 11.0 0.0 6.5 1.0 7.6 1.9 5.5 1.3 5.1 3.4 7.4 5.4 1.7 2.1 3.8 4.3 4.5 2.0 8.5 8.2 9.7 5.0 5.1 15.3 0.0 6.2 4.4 6.1 17.6 10.3 3.1 2.1 24.2 1.8 1.9 7.8 2.0 1.0 2.0 39.2 8.0 11.2 1.5 0.5 11.4 10.5 8.2 7.2 0.2 6.6 5.3 6.0 17.1 16.7 8.4 10.2 9.2 4.3 4.6 6.7 10.2 LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 106.6;granulocytes: 109.3;Hofbauer cells: 190.9;Kupffer cells: 100.9;Macrophages: 128.9;NK-cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 7.5;Karpas-707: 19.4;THP-1: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" 23.3 11.6 0.5 3.0 0.3 4.4 12.3 1.6 1.3 4.1 0.5 6.9 0.4 3.8 0.2 2.6 5.5 0.9 3.8 0.4 0.6 4.6 3.5 28.1 5.8 1.0 0.8 2.2 3.8 0.1 4.4 1.0 1.0 5.4 0.2 0.1 5.8 0.2 1.3 2.1 14.3 2.0 0.4 46.3 5.0 1.7 1.1 3.9 3.3 0.1 0.9 6.3 3.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 3.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 19.4 0.0 0.0 2.6 1.8 0.0 0.0 0.0 2.6 0.2 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 22.9 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 3.2 0.3 13.1 4.2 11.7 7.7 9.8 4.8 2.1 2.3 4.1 0.1 5.8 3.4 4.4 0.7 6.3 11.0 11.2 1.7 3.8 0.5 0.3 1.6 1.3 0.4 0.6 1.0 0.8 1.0 0.4 1.1 0.9 1.9 16.0 25.6 0.3 26.1 0.6 0.6 0.2 0.0 5.6 1.1 2.9 1.5 1.5 11.2 0.0 37.5 5.3 106.6 0.2 0.0 0.1 32.2 0.6 0.7 5.0 0.0 10.9 0.4 0.0 5.2 2.5 0.0 0.7 109.3 0.6 3.6 1.2 190.9 1.7 0.5 0.0 0.0 100.9 17.7 26.1 0.3 128.9 0.0 13.1 22.5 0.9 98.9 0.0 0.6 0.1 0.0 0.0 5.1 0.7 0.3 0.3 11.0 15.4 0.0 0.9 1.3 2.9 1.0 0.4 1.1 10.0 32.1 0.2 0.2 0.9 LAMP1 CD107a ENSG00000185896 "Lysosomal associated membrane protein 1" P11279 13 113297239-113323672 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 709.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004260, HPA014750" Supported NA NA 370000000 "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB004260: AB_626851, HPA014750: AB_1846219" "unprognostic (3.98e-1)" "unprognostic (1.18e-1)" "unprognostic (7.55e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.04e-3)" "unprognostic (9.26e-2)" "unprognostic (1.07e-1)" "unprognostic (5.80e-2)" "unprognostic (1.44e-2)" "unprognostic (2.91e-3)" "unprognostic (2.04e-1)" "prognostic favorable (4.15e-5)" "unprognostic (2.06e-2)" "unprognostic (2.22e-1)" "unprognostic (2.59e-1)" "unprognostic (1.54e-1)" 139.2 95.3 83.6 84.1 118.7 72.1 124.6 114.3 89.9 119.3 54.5 108.0 109.8 136.0 103.4 125.1 98.7 91.3 101.3 82.9 96.9 149.1 183.8 148.7 77.2 120.6 106.5 101.7 174.3 109.9 95.0 107.9 119.7 98.0 65.9 35.7 145.0 94.8 71.3 182.3 112.7 92.5 104.7 102.3 108.5 84.8 112.6 63.4 126.7 46.6 55.6 118.6 110.9 138.0 271.7 92.3 93.9 258.1 514.7 192.5 176.7 311.9 325.1 189.8 252.1 181.8 491.1 63.7 139.1 318.6 324.9 338.7 92.9 198.1 128.7 133.8 153.1 105.5 167.6 172.5 265.9 324.5 236.2 236.4 264.6 176.3 114.4 308.4 232.2 61.0 89.3 90.9 236.8 108.9 66.0 158.2 71.5 258.4 99.9 96.1 81.4 96.5 172.3 200.9 85.7 90.1 183.3 268.5 187.6 89.8 259.6 228.0 355.1 193.5 208.2 258.8 141.4 169.4 178.8 66.6 323.4 318.8 229.7 3.8 4.9 9.5 4.0 4.0 3.4 2.2 3.1 4.4 2.5 2.1 3.4 2.8 6.8 3.9 4.4 5.4 3.6 2.1 83.6 118.7 114.3 89.9 82.9 96.9 120.6 106.5 119.7 104.7 112.6 138.0 152.4 86.6 67.2 31.3 64.5 140.8 144.5 68.3 70.0 42.4 131.1 92.5 56.9 123.0 51.4 183.9 77.2 195.6 103.6 248.7 41.1 99.0 272.1 72.7 73.4 113.9 119.2 50.9 22.3 62.3 198.5 173.6 60.6 101.3 71.0 71.3 162.1 303.3 282.9 30.3 22.4 111.1 32.6 208.9 56.8 709.0 163.8 167.6 99.6 34.7 77.6 50.1 104.0 29.7 83.2 82.7 199.2 170.4 51.8 101.4 288.1 178.1 45.1 84.5 118.3 85.0 107.1 163.1 124.7 96.1 197.5 312.4 94.8 72.4 128.6 124.0 LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748679 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1448.9;Macrophages: 346.1;Syncytiotrophoblasts: 416.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 209.2" "Lineage enriched" "Detected in all" 12 "dendritic cells: 209.2" "Cell line enhanced" "Detected in many" "RPMI-8226: 898.6;U-266/70: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favorable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" 173.7 44.4 37.6 82.2 38.6 20.6 69.7 31.7 60.8 52.6 51.2 102.5 110.4 30.8 36.8 64.5 36.6 145.8 85.3 40.0 40.3 205.9 111.1 107.3 177.0 35.6 37.3 33.0 37.9 247.0 24.9 262.1 42.4 51.9 105.9 19.7 56.4 32.2 50.4 32.7 97.6 65.0 35.9 202.2 107.0 29.8 62.8 52.8 93.2 50.4 54.9 144.7 52.1 49.4 33.2 47.5 30.8 57.4 94.3 76.0 108.4 70.3 67.0 71.7 84.2 36.9 58.6 18.2 101.5 116.5 44.3 81.5 0.0 60.8 33.7 1.6 36.2 1.2 24.4 42.8 27.7 1.0 2.7 54.2 29.1 68.4 39.4 21.3 82.1 33.7 7.4 150.9 5.2 45.2 8.9 1.2 15.1 208.2 32.1 8.4 27.1 898.6 59.2 129.1 33.6 23.2 97.9 59.4 53.0 66.8 43.9 0.6 47.2 35.3 44.8 64.5 21.8 462.5 58.0 25.0 20.0 0.2 69.1 1.9 1.6 0.1 0.8 3.1 1.6 17.0 5.1 1.3 19.3 14.5 15.2 9.0 1.6 3.7 1.0 209.2 9.7 7.0 37.6 38.6 31.7 60.8 40.0 40.3 35.6 37.3 42.4 35.9 62.8 49.4 34.9 57.7 128.0 8.8 33.9 23.1 37.5 36.0 22.2 10.6 31.2 37.6 29.8 42.9 48.1 31.3 93.8 181.8 24.5 64.2 9.8 61.3 1.3 79.4 23.5 38.3 36.5 22.7 19.2 50.6 140.2 63.8 73.4 177.7 8.8 17.6 276.3 46.4 1448.9 13.5 41.0 31.1 95.6 317.6 89.0 3.3 30.4 346.1 48.0 27.2 37.5 23.6 2.1 10.6 15.2 50.5 57.1 57.9 24.7 44.6 163.4 220.4 20.9 19.8 19.7 40.4 62.1 19.9 17.6 22.3 17.5 416.3 8.2 15.1 48.3 44.7 LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 76.9;Hofbauer cells: 127.6;Kupffer cells: 118.9;Macrophages: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cell line enriched" "Detected in some" 32 "Karpas-707: 407.8" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" 8.6 4.6 2.2 10.9 2.5 2.0 3.6 2.7 4.2 1.1 2.2 4.1 1.6 0.9 0.3 1.0 4.0 1.7 2.3 2.2 2.8 2.2 2.9 13.7 11.4 3.8 3.2 0.7 1.6 0.1 2.2 1.4 3.5 1.9 2.3 0.1 3.6 0.3 0.5 0.5 6.3 0.7 3.2 18.8 1.7 0.3 3.0 0.6 2.4 0.0 2.1 6.1 0.8 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 407.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.4 12.8 0.0 0.2 0.0 0.4 0.0 7.8 0.0 0.0 10.8 0.0 0.2 0.0 0.0 11.7 0.5 0.0 0.0 0.1 0.1 8.9 37.3 0.0 3.8 2.2 2.5 2.7 4.2 2.2 2.8 3.8 3.2 3.5 3.2 3.0 3.3 0.6 0.0 4.1 0.0 13.4 0.4 0.0 0.0 0.0 0.2 0.3 1.7 1.0 1.5 1.3 0.0 0.0 0.3 76.9 0.1 0.0 0.0 0.2 0.0 0.0 4.2 0.0 7.8 0.1 0.0 0.9 0.5 0.0 0.0 1.3 0.0 2.2 0.8 127.6 0.0 0.2 0.0 0.0 118.9 12.6 0.6 0.0 104.0 1.8 14.0 29.3 0.2 1.0 0.0 0.0 0.1 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.2 6.6 0.2 0.1 0.0 0.4 0.1 0.1 0.8 2.2 0.0 0.2 0.1 LILRB5 "CD85c, LIR-8, LIR8" ENSG00000105609 "Leukocyte immunoglobulin like receptor B5" O75023 19 54249421-54257301 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.9;lymphoid tissue: 49.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 61.1;Kupffer cells: 103.4;Macrophages: 40.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012069 Approved NA NA 58000000 "Cluster 17: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA012069: AB_1852873" "unprognostic (3.55e-3)" "unprognostic (5.38e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-2)" "unprognostic (8.86e-2)" "unprognostic (5.44e-2)" "unprognostic (3.02e-5)" "unprognostic (6.80e-2)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (4.14e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" 17.9 10.3 0.2 1.7 0.5 0.9 7.2 0.3 1.0 1.6 1.3 6.1 4.6 1.1 0.8 1.8 4.4 2.8 5.1 0.2 0.2 1.6 7.1 5.3 1.8 0.5 0.3 1.3 0.8 0.3 0.7 4.8 0.4 0.6 4.8 0.1 2.9 0.6 1.8 2.3 6.8 2.4 0.2 49.1 2.5 1.1 1.0 1.0 1.4 1.3 0.7 4.2 1.2 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.5 0.3 1.0 0.2 0.2 0.5 0.3 0.4 0.2 1.0 1.1 0.5 0.0 1.1 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 1.7 0.0 0.1 0.2 0.0 2.7 0.0 0.0 0.4 0.7 0.0 0.1 0.0 0.1 8.6 0.9 61.1 0.0 0.0 0.0 0.0 103.4 9.8 1.8 0.0 40.1 1.8 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.5 0.0 0.1 0.3 1.1 0.8 0.4 0.5 0.0 0.0 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 27.6;Horizontal cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 136.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Cytosol" "HPA028516: AB_10601751, HPA073571: " "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 11.1 10.5 31.1 18.7 32.7 6.8 9.4 28.3 77.9 21.4 0.2 8.9 6.6 13.1 3.5 11.3 7.3 10.1 9.4 35.0 43.8 10.8 4.6 13.2 23.5 75.5 40.0 13.2 11.4 5.8 13.9 7.3 73.0 12.3 4.1 4.0 17.9 8.2 23.7 11.4 12.1 7.1 31.8 22.3 9.2 15.6 59.1 8.1 11.2 7.8 18.2 13.1 14.7 38.3 47.4 37.2 27.2 45.4 35.1 47.0 20.0 28.8 27.3 22.6 25.4 21.3 45.6 30.2 12.7 35.5 76.9 28.1 10.1 17.8 8.6 53.7 18.6 23.2 13.1 24.6 40.5 17.2 81.4 46.8 15.6 18.5 9.6 68.3 34.4 20.9 15.1 9.0 28.8 41.4 14.8 31.4 52.1 16.6 23.7 21.1 43.3 18.2 26.5 10.1 10.7 25.2 18.6 43.7 23.5 29.7 13.9 15.4 41.1 36.0 33.7 94.5 47.7 10.2 12.5 54.9 136.5 12.4 25.2 0.1 6.1 3.5 1.8 6.0 1.4 3.4 0.4 1.2 7.0 1.7 0.1 0.5 0.5 5.8 3.8 0.7 0.3 3.3 31.1 32.7 28.3 77.9 35.0 43.8 75.5 40.0 73.0 31.8 59.1 38.3 2.9 3.2 2.7 7.5 14.4 2.9 5.2 6.6 1.8 6.6 7.7 6.9 3.4 7.2 3.8 1.8 2.1 2.5 11.9 2.9 0.0 6.6 1.2 2.7 9.7 4.1 2.4 0.4 15.4 6.5 6.3 9.2 3.1 5.1 5.7 27.6 3.3 2.1 25.0 35.3 20.8 2.7 0.0 13.5 10.8 2.2 7.2 15.6 3.6 6.5 14.9 3.5 22.6 6.6 2.4 13.5 2.3 6.0 10.0 9.0 0.3 2.8 3.1 3.3 0.0 5.3 4.5 3.4 11.5 1.8 3.1 3.7 11.1 6.9 2.4 7.2 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 LYVE1 "LYVE-1, XLKD1" ENSG00000133800 "Lymphatic vessel endothelial hyaluronan receptor 1" Q9Y5Y7 11 10556966-10611689 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 126.4;placenta: 149.3" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 238.8;Hofbauer cells: 807.4;Kupffer cells: 338.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HUVEC TERT2: 81.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.8" "CAB025860, HPA042953" Supported NA NA 3300000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB025860: , HPA042953: AB_2678238" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "unprognostic (1.87e-1)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.53e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.98e-5)" "unprognostic (1.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-3)" 126.4 68.9 2.7 19.3 3.5 0.9 37.3 2.0 5.1 17.6 8.9 19.9 13.3 8.1 5.7 26.2 23.0 20.2 13.5 2.9 2.4 8.1 44.2 23.8 8.4 3.0 2.2 11.8 4.9 2.3 2.7 149.3 3.1 4.0 20.0 0.3 5.4 11.2 5.0 7.1 17.6 67.1 2.1 61.6 10.5 4.3 3.3 1.7 13.5 27.4 3.0 35.1 6.8 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 81.6 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 3.5 2.0 5.1 2.9 2.4 3.0 2.2 3.1 2.1 3.3 3.2 5.7 0.0 2.8 8.1 2.1 3.7 0.1 0.0 0.0 0.0 0.5 0.3 4.6 8.6 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 1.0 0.0 0.2 102.7 0.0 5.3 0.8 0.0 5.7 3.4 0.0 0.0 1.3 0.0 238.8 4.5 807.4 0.0 0.4 0.0 0.0 338.1 10.7 2.3 3.7 86.0 7.2 12.2 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.4 2.7 0.2 0.0 0.0 1.5 0.0 13.1 3.4 6.8 0.0 0.0 1.4 3.3 11.1 1.4 0.7 0.0 0.2 M6PR "CD-M6PR, CD-MPR" ENSG00000003056 "Mannose-6-phosphate receptor, cation dependent" P20645 12 8940361-8949761 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 242.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 859.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034464, HPA040445" Approved NA NA 100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB034464: AB_2139108, HPA040445: AB_2676989" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.54e-1)" "unprognostic (3.00e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "unprognostic (5.82e-3)" "unprognostic (1.44e-2)" "unprognostic (6.82e-2)" "unprognostic (4.53e-3)" "unprognostic (3.79e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (3.98e-1)" 76.6 64.8 79.5 113.9 83.3 104.1 81.5 80.7 95.5 61.5 79.2 78.4 61.1 73.7 63.1 63.3 70.4 74.0 82.0 83.5 85.9 79.1 78.9 97.5 138.8 85.7 83.8 62.8 59.6 95.0 34.0 78.6 86.2 64.9 91.8 73.7 79.2 74.5 51.9 60.4 64.5 81.1 84.0 132.5 74.8 59.7 90.8 105.4 96.4 56.0 125.4 98.0 37.5 96.4 103.6 159.7 103.0 122.0 187.7 86.8 306.2 129.7 159.4 186.2 210.7 176.4 268.4 188.9 48.9 133.0 374.4 160.0 142.7 131.2 218.8 859.9 86.6 331.3 125.0 122.4 213.7 355.6 566.6 126.0 166.3 184.4 232.5 179.2 105.5 123.3 93.0 114.6 165.2 103.7 120.7 142.3 412.8 189.0 72.4 118.0 248.0 108.4 151.9 241.2 26.5 109.9 159.8 159.4 223.9 363.8 39.0 251.3 106.0 156.3 175.1 186.6 193.2 139.3 253.5 201.4 183.2 226.4 120.5 706.9 292.0 319.1 177.4 477.6 201.5 123.2 210.7 195.5 334.0 111.4 152.7 170.6 44.5 186.3 567.4 205.0 182.3 497.3 79.5 83.3 80.7 95.5 83.5 85.9 85.7 83.8 86.2 84.0 90.8 96.4 49.9 57.7 57.0 13.4 75.2 44.1 73.0 73.1 43.9 46.1 50.1 40.8 10.7 44.3 68.0 31.3 22.9 64.4 107.0 23.4 19.6 91.8 7.9 31.3 36.7 39.6 38.3 60.1 25.9 66.9 71.4 37.2 30.5 33.7 132.3 39.9 37.1 28.3 242.8 55.5 29.0 30.5 40.7 138.9 95.4 7.9 35.1 166.4 67.6 21.5 212.2 35.8 159.6 17.1 22.7 56.1 29.5 32.0 73.7 65.4 25.7 41.8 53.1 37.4 26.3 52.5 43.7 117.5 54.4 51.6 40.5 53.1 96.4 55.8 43.8 68.2 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 74.5" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 37.0;Fibroblasts: 38.7;Inhibitory neurons: 42.9;Leydig cells: 96.6;Microglial cells: 45.9;Peritubular cells: 82.0;Sertoli cells: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.7;HHSteC: 57.2;LHCN-M2: 75.0;TIME: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" 17.2 8.2 1.0 1.2 1.2 0.2 15.6 0.8 1.6 30.4 2.3 45.5 8.4 74.5 19.1 21.2 58.5 13.0 15.4 0.7 1.5 2.6 1.2 37.2 0.5 0.7 1.2 49.1 3.7 1.8 0.8 4.3 0.7 7.7 12.3 5.7 9.9 10.8 6.6 9.2 21.6 25.3 0.7 16.1 19.1 7.5 1.8 1.6 8.0 17.1 3.1 32.3 18.5 1.1 0.3 0.0 0.7 0.0 55.7 18.8 1.7 11.1 5.0 2.7 4.6 0.0 1.2 0.0 0.7 2.1 1.5 9.1 0.1 0.8 2.3 0.0 0.0 0.0 15.6 0.1 57.2 0.0 0.0 3.6 0.7 1.7 0.9 19.9 4.9 0.0 0.0 0.5 75.0 0.0 0.0 0.1 7.7 0.1 0.0 0.0 8.8 7.3 24.6 0.0 0.7 0.0 0.1 0.1 0.0 20.8 0.0 0.0 71.0 0.0 1.8 0.1 2.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.6 0.7 1.5 0.7 1.2 0.7 0.7 1.8 1.1 2.0 0.0 1.5 20.2 0.5 6.1 0.5 0.4 0.6 0.8 0.5 10.8 4.3 0.0 0.1 3.7 4.2 0.2 0.2 0.2 0.0 0.1 42.5 0.7 13.7 3.9 0.0 0.0 37.0 0.2 6.6 38.7 0.5 0.5 1.3 0.3 0.4 0.0 3.3 0.0 42.9 0.1 0.0 0.0 17.5 11.4 96.6 13.6 10.6 45.9 0.0 13.8 0.0 11.6 23.3 0.4 0.2 82.0 0.0 0.1 0.0 0.5 0.1 0.5 39.5 4.8 22.4 0.4 0.4 1.1 4.8 0.3 0.8 0.1 0.1 0.1 MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177205-119349761 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 154.6" "Cell type enhanced" "Detected in many" "Early spermatids: 232.5;Excitatory neurons: 165.0;Hepatocytes: 270.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 273.1;Hep G2: 204.0;Karpas-707: 219.6;U-266/70: 294.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" NA NA 460000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "CAB037058: AB_477183, HPA053198: AB_2682078, HPA063561: AB_2685042" "unprognostic (1.50e-1)" "unprognostic (7.36e-3)" "unprognostic (4.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.33e-3)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-3)" "unprognostic (4.62e-1)" "unprognostic (2.37e-2)" "unprognostic (3.49e-2)" "unprognostic (2.25e-1)" "unprognostic (6.89e-2)" "unprognostic (3.40e-1)" 102.2 48.5 4.2 32.8 12.3 28.9 34.3 1.2 8.9 25.9 5.1 36.1 52.7 23.8 8.8 22.7 16.0 47.1 15.3 8.0 4.6 66.6 154.6 35.8 34.8 2.9 5.0 20.1 32.7 25.8 4.6 79.4 2.5 18.1 29.3 6.2 42.7 15.0 7.6 14.3 69.8 27.2 3.3 36.5 25.9 7.0 8.4 18.9 22.6 31.0 25.9 56.0 17.1 5.9 0.2 0.0 3.4 0.0 273.1 119.9 6.6 6.9 41.4 5.1 12.5 19.8 2.6 43.2 0.3 26.5 65.7 0.4 7.6 0.1 6.4 64.5 19.4 36.3 3.9 204.0 27.2 0.1 17.7 82.4 5.3 41.6 25.3 22.1 3.4 12.6 128.1 219.6 39.7 6.1 1.7 0.3 2.3 20.0 10.0 12.1 4.2 66.6 13.4 35.4 14.1 21.0 0.1 0.6 0.0 8.3 10.4 4.8 24.8 16.9 15.4 32.0 15.8 294.5 44.6 84.8 50.2 0.7 10.4 4.3 0.3 1.1 1.1 0.5 2.3 0.7 0.6 0.6 0.3 0.4 0.3 0.9 1.9 0.9 0.5 2.8 0.7 0.3 4.2 12.3 1.2 8.9 8.0 4.6 2.9 5.0 2.5 3.3 8.4 5.9 37.1 9.6 46.1 19.9 31.0 31.7 5.7 1.2 5.2 28.1 18.8 5.8 4.4 44.3 6.9 106.7 0.0 6.8 40.6 23.3 5.9 9.4 232.5 5.9 63.9 42.1 48.0 40.4 165.0 37.8 12.4 98.4 18.8 10.7 3.8 24.0 97.5 270.5 101.1 0.0 79.4 61.1 0.0 84.6 91.2 39.3 26.4 98.0 28.4 128.4 13.5 1.7 42.2 4.5 3.7 14.8 18.9 4.1 147.5 5.3 92.2 33.5 4.6 5.0 6.6 12.9 27.8 2.8 3.9 3.4 27.8 6.2 24.3 14.6 18.9 9.7 MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 109.4;Kupffer cells: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 117.5;classical monocyte: 45.2;eosinophil: 105.7;intermediate monocyte: 95.5;neutrophil: 41.1;non-classical monocyte: 105.1" "Group enriched" "Detected in all" 5 "granulocytes: 117.5;monocytes: 105.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" 21.2 37.4 6.4 9.2 6.5 10.4 15.3 7.0 8.4 11.7 8.3 13.6 8.3 11.6 2.7 11.0 12.2 10.1 15.7 7.0 7.4 11.7 14.7 20.3 13.2 8.2 7.4 10.0 9.9 10.2 21.7 15.9 9.0 8.7 5.6 5.0 12.3 6.1 22.2 20.8 12.1 8.1 7.1 48.2 12.8 5.6 8.2 6.2 8.5 11.7 4.1 15.8 10.9 9.9 11.6 11.7 5.6 19.1 32.0 10.3 16.1 21.2 16.9 25.2 21.6 9.0 10.0 6.5 25.5 14.5 22.2 5.3 9.5 7.3 7.4 12.7 21.1 5.8 11.0 7.3 28.0 6.6 24.5 14.5 16.8 24.1 4.2 7.9 10.7 14.2 10.9 27.9 14.7 3.9 9.1 6.6 12.6 6.1 24.8 12.6 9.4 13.8 9.6 9.9 14.4 17.8 9.1 15.8 26.8 6.1 9.6 11.4 13.5 12.0 6.9 48.8 16.0 21.5 35.5 4.7 19.2 9.2 18.4 117.5 45.2 105.7 7.7 95.5 6.3 4.2 6.5 6.3 19.2 4.1 6.0 6.5 41.1 10.3 105.1 21.1 10.0 17.1 6.4 6.5 7.0 8.4 7.0 7.4 8.2 7.4 9.0 7.1 8.2 9.9 15.1 3.2 2.6 5.9 8.0 13.4 6.5 16.9 10.2 27.3 15.9 15.0 2.3 15.7 8.1 31.3 22.9 11.6 12.1 32.0 1.9 23.7 4.8 5.0 19.8 14.1 16.8 21.7 10.6 23.1 20.0 16.0 9.7 6.5 1.3 22.2 13.6 13.6 109.4 58.9 8.0 10.0 22.4 117.1 32.2 17.0 16.4 70.6 21.4 7.5 18.0 23.0 16.5 7.5 11.4 23.4 19.3 15.8 8.0 5.6 21.8 12.3 6.5 44.1 6.6 11.2 14.8 10.3 14.7 8.9 17.3 29.6 8.7 17.3 9.4 4.8 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 162.6;Kupffer cells: 119.8;Macrophages: 46.5;Microglial cells: 124.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 8.6;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.6" "Cell line enhanced" "Detected in many" "CACO-2: 35.1;Hep G2: 39.9;HUVEC TERT2: 38.4;RT4: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" Yes NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: AB_2686759" "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favorable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 59.8 22.8 13.5 28.0 1.5 15.3 18.0 29.3 12.6 44.7 10.9 12.3 11.5 26.3 8.4 15.5 12.0 7.0 22.0 22.5 11.4 21.0 13.6 13.1 23.5 22.3 12.6 9.9 21.2 15.5 20.1 22.4 14.1 7.9 16.6 6.4 16.3 3.2 6.4 14.3 14.4 18.4 30.6 13.9 17.2 30.1 6.8 10.1 4.6 8.9 13.6 9.4 22.0 1.0 1.7 7.6 17.3 0.4 0.2 12.3 0.0 0.2 1.0 1.7 35.1 2.2 0.1 8.1 0.1 7.9 0.2 10.2 0.0 1.4 1.5 5.5 7.0 0.0 39.9 0.3 0.2 1.5 0.5 0.0 8.9 0.6 4.0 38.4 1.5 2.2 3.5 2.9 1.8 0.0 9.1 4.8 1.1 6.0 2.9 2.1 3.0 19.4 23.4 0.3 7.2 0.2 0.5 3.2 2.7 0.0 0.4 5.8 1.0 3.4 0.1 0.0 3.1 4.8 0.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.5 0.1 0.0 0.2 22.8 28.0 18.0 29.3 22.0 22.5 23.5 22.3 22.4 18.4 30.1 22.0 8.8 3.2 27.7 162.6 1.7 1.7 2.9 0.3 1.8 0.6 2.1 4.3 2.7 2.8 6.4 0.0 2.1 3.3 0.4 1.2 1.9 1.1 2.3 8.0 4.7 10.2 0.0 0.4 5.0 1.0 1.1 3.2 0.5 12.1 0.0 3.8 28.5 9.2 25.5 0.0 7.0 2.0 0.0 119.8 1.8 2.7 5.0 46.5 0.0 124.6 1.5 7.7 0.0 10.6 0.6 1.2 1.9 6.8 10.8 2.9 4.4 1.9 1.5 11.3 6.6 1.5 9.2 0.6 1.5 0.6 1.3 18.9 1.3 3.5 1.9 1.6 MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 214.4;Kupffer cells: 289.7;Macrophages: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" 39.7 27.4 11.0 38.1 12.9 35.9 26.9 20.2 15.8 22.5 23.8 31.1 25.7 16.1 19.4 35.0 21.4 32.3 17.2 15.7 14.5 30.3 39.5 40.5 34.5 15.8 12.2 17.9 31.5 36.0 7.5 30.7 16.4 26.8 22.2 8.4 48.4 23.4 11.1 23.4 23.2 26.2 11.5 42.0 36.1 18.0 16.1 16.1 27.9 16.9 21.5 40.0 19.6 17.3 83.3 28.9 9.1 26.3 51.0 45.0 35.9 109.7 61.8 46.5 45.9 10.3 82.8 19.7 73.5 81.9 24.1 37.0 22.0 26.7 40.9 68.2 33.7 57.2 24.0 6.7 52.1 206.0 135.7 59.3 38.5 39.7 9.5 15.9 38.0 14.0 39.9 32.9 85.1 19.2 11.3 83.2 8.5 29.9 50.9 19.8 11.3 170.9 18.1 16.3 18.2 29.8 76.7 70.0 25.0 8.3 56.9 100.1 102.8 58.6 23.2 87.3 60.5 98.3 94.4 9.6 74.1 162.0 39.7 102.4 288.8 246.0 36.6 223.4 35.3 54.2 30.3 33.9 254.5 44.5 32.2 35.5 97.1 32.9 187.8 81.8 38.9 252.1 11.0 12.9 20.2 15.8 15.7 14.5 15.8 12.2 16.4 11.5 16.1 17.3 28.5 19.2 34.0 12.1 39.6 21.4 46.2 38.4 33.0 11.8 33.3 19.7 22.2 20.0 51.6 22.0 6.2 27.5 24.1 33.3 19.6 34.0 5.3 13.6 22.7 28.2 22.8 56.0 14.6 28.5 33.6 33.7 23.9 17.2 48.8 8.9 37.1 34.4 214.4 18.5 15.2 28.6 34.6 289.7 90.7 6.7 12.2 212.3 32.0 16.9 88.7 26.0 25.7 15.1 29.4 29.0 29.9 11.3 32.9 30.0 27.1 31.8 59.3 10.5 13.1 11.8 23.8 11.6 8.7 61.2 26.0 56.0 22.3 19.4 28.3 58.4 MFSD13A "bA18I14.8, C10orf77, FLJ22529, TMEM180" ENSG00000138111 "Major facilitator superfamily domain containing 13A" Q14CX5 10 102461395-102477045 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Alveolar cells type 2: 15.4;Hofbauer cells: 15.7;Horizontal cells: 21.9;Syncytiotrophoblasts: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018031 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Cytosol" "HPA018031: AB_2204891" "unprognostic (2.24e-2)" "prognostic favorable (8.29e-4)" "unprognostic (7.73e-2)" "unprognostic (1.13e-1)" "unprognostic (2.79e-1)" "unprognostic (2.11e-1)" "unprognostic (9.16e-3)" "unprognostic (4.70e-2)" "unprognostic (4.03e-2)" "unprognostic (8.10e-2)" "unprognostic (2.04e-1)" "unprognostic (3.82e-2)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.66e-3)" "unprognostic (2.44e-1)" "unprognostic (2.74e-1)" "unprognostic (4.02e-2)" 2.3 2.5 10.0 3.2 13.0 5.2 2.1 14.1 12.8 2.4 2.3 5.0 5.5 3.1 0.7 3.0 2.3 2.3 3.2 10.8 7.2 2.5 6.3 9.0 3.2 7.7 7.7 1.4 3.8 1.7 4.1 2.3 7.8 3.1 3.2 4.9 1.8 0.9 2.3 11.7 4.4 2.5 6.5 6.9 4.0 3.7 9.2 1.8 5.4 1.4 3.6 2.2 2.6 9.4 12.0 5.4 4.0 9.6 0.4 0.4 6.2 2.3 6.0 4.6 10.5 10.7 16.0 10.6 11.8 0.9 4.4 14.6 7.4 6.3 1.7 13.5 6.8 13.1 8.2 5.6 10.1 6.7 12.3 5.2 2.6 2.6 4.6 3.7 5.3 14.2 3.0 5.7 0.4 2.4 11.3 4.3 6.8 10.5 5.2 13.6 0.6 1.8 2.0 3.1 10.0 9.5 2.2 1.2 5.2 1.4 6.0 4.0 1.6 2.1 2.5 2.6 3.3 1.9 5.5 14.0 11.6 10.9 2.9 0.4 4.3 3.5 2.9 3.2 2.8 3.4 2.7 2.3 4.5 1.4 2.8 3.2 2.5 1.2 1.8 0.4 0.8 2.6 10.0 13.0 14.1 12.8 10.8 7.2 7.7 7.7 7.8 6.5 9.2 9.4 4.1 19.2 15.4 0.0 1.1 0.0 1.5 0.0 0.6 8.2 1.5 1.9 0.0 1.5 0.6 1.8 4.2 1.8 5.7 2.6 0.0 2.8 1.8 1.0 1.0 3.8 2.4 3.6 0.0 3.6 2.6 1.6 5.6 1.6 1.3 2.8 6.4 4.0 15.7 21.9 0.0 3.8 0.0 4.8 0.0 1.0 0.9 8.7 0.0 0.0 5.6 3.2 2.1 0.0 0.0 3.2 4.6 2.2 0.8 1.4 5.6 1.5 0.7 13.8 0.0 2.8 1.1 4.5 3.0 2.4 0.0 28.5 3.2 4.0 4.5 1.4 MILR1 "Allergin-1, C17orf60, MCA-32" ENSG00000271605 "Mast cell immunoglobulin like receptor 1" Q7Z6M3 17 64449037-64468643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.3" "Cell type enhanced" "Detected in many" "dendritic cells: 40.5;granulocytes: 34.8;Hofbauer cells: 78.5;Kupffer cells: 33.3;Macrophages: 30.1;Microglial cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 85.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 47.4;CAPAN-2: 120.3;Daudi: 60.4;REH: 45.6;U-698: 63.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014347 Enhanced NA NA 50000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA014347: AB_2732408" "unprognostic (8.40e-2)" "unprognostic (9.77e-2)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (1.17e-1)" "unprognostic (1.21e-2)" "unprognostic (1.27e-2)" "unprognostic (1.22e-1)" "unprognostic (3.25e-1)" "unprognostic (3.31e-2)" "unprognostic (5.99e-3)" "unprognostic (4.78e-2)" "prognostic unfavorable (5.07e-6)" "unprognostic (2.51e-2)" "unprognostic (7.12e-3)" "unprognostic (1.09e-1)" "unprognostic (5.99e-2)" 8.4 5.0 3.7 25.3 4.1 17.8 5.0 3.6 5.1 7.3 4.3 4.9 4.7 3.4 4.3 3.0 2.7 8.1 4.7 3.9 4.0 2.7 4.0 9.4 24.3 7.3 5.5 3.0 1.8 1.8 1.8 16.3 6.9 2.8 8.4 0.8 3.4 2.4 1.3 1.8 5.9 8.3 5.5 17.0 3.0 2.4 6.7 4.3 2.7 0.7 21.3 8.9 2.1 9.5 7.2 1.7 0.2 0.3 4.5 47.4 0.6 0.1 5.2 0.9 10.3 0.1 120.3 60.4 2.6 0.5 23.2 1.4 0.0 2.0 3.1 0.0 0.1 1.5 1.2 0.0 1.0 4.0 37.2 4.4 0.3 13.7 2.1 5.8 4.5 0.5 4.4 6.9 29.2 0.0 0.7 8.7 0.4 0.8 8.6 45.6 8.1 27.1 1.8 0.4 0.2 0.1 3.9 0.4 8.2 0.0 0.4 35.0 16.0 0.3 1.5 0.1 2.9 0.4 0.1 63.6 30.3 7.2 0.0 85.0 47.3 2.8 0.9 40.2 0.7 25.9 0.6 0.6 30.6 16.7 0.7 0.8 14.0 1.5 27.8 53.9 0.6 14.5 3.7 4.1 3.6 5.1 3.9 4.0 7.3 5.5 6.9 5.5 6.7 9.5 3.0 0.0 0.5 0.3 7.5 0.5 2.7 2.7 0.6 0.4 3.1 1.9 0.7 1.5 2.1 0.0 0.0 0.7 40.5 1.1 0.0 0.1 0.7 1.4 2.3 2.7 4.9 1.7 0.5 0.0 2.4 6.1 0.5 2.1 34.8 2.8 1.8 0.1 78.5 0.0 0.5 0.7 2.0 33.3 13.9 0.4 4.1 30.1 0.0 43.1 10.1 0.5 4.1 1.5 0.5 0.0 1.4 1.5 1.2 2.4 0.2 0.0 0.2 1.4 0.0 14.9 3.0 0.3 0.4 0.2 1.7 1.2 1.5 0.1 1.9 2.4 MKNK1 MNK1 ENSG00000079277 "MAPK interacting serine/threonine kinase 1" Q9BUB5 1 46557407-46616843 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 128.6" "Cell type enhanced" "Detected in all" "Hofbauer cells: 142.8;Microglial cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: AB_2686382" "unprognostic (4.05e-3)" "prognostic favorable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavorable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" 30.6 21.8 15.5 23.5 14.4 30.3 23.1 19.0 18.0 22.8 17.0 27.4 15.6 18.5 12.0 23.5 21.4 16.1 22.3 15.1 14.6 17.5 21.8 31.5 17.0 14.2 13.3 19.0 128.6 12.0 18.4 22.1 14.4 19.4 17.7 3.9 16.7 8.5 23.9 18.0 24.9 18.4 13.7 48.1 23.1 12.4 16.6 22.6 16.2 23.9 13.8 20.1 20.7 16.5 34.1 21.7 13.5 15.7 12.0 17.9 18.0 16.7 16.4 20.7 27.1 26.4 13.5 23.1 20.2 17.8 23.0 38.5 23.8 27.5 23.1 37.7 21.4 47.8 28.3 21.7 17.3 25.4 34.8 22.0 17.7 25.2 13.4 10.8 24.1 26.2 24.7 16.6 12.2 21.5 18.3 21.8 9.9 19.6 24.8 16.7 30.5 22.1 20.2 35.2 10.4 9.0 32.3 27.9 25.6 26.5 21.5 28.6 18.5 7.6 1.4 22.2 19.9 12.6 23.7 21.2 14.6 31.9 13.4 9.7 26.3 36.1 15.3 25.7 44.7 9.9 12.9 14.2 13.1 11.6 9.2 13.9 69.7 11.2 20.6 9.7 10.6 14.5 15.5 14.4 19.0 18.0 15.1 14.6 14.2 13.3 14.4 13.7 16.6 16.5 20.3 12.8 21.5 41.4 15.3 13.9 17.8 15.2 9.1 19.4 17.8 12.3 19.2 15.7 17.8 22.0 2.1 21.6 23.7 27.9 7.9 18.9 15.5 12.5 12.8 18.3 16.8 21.9 42.2 37.1 34.2 20.5 11.7 13.3 12.0 22.8 18.2 22.7 142.8 18.5 52.7 12.0 4.1 84.5 61.0 23.8 21.5 49.9 10.6 100.2 26.7 5.2 21.6 21.6 8.5 32.3 17.7 36.5 13.3 19.5 27.8 15.7 11.1 5.0 6.6 31.2 15.0 15.3 17.2 22.6 11.1 18.5 25.2 35.1 15.0 29.6 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MS4A4E ENSG00000214787 "Membrane spanning 4-domains A4E" Q96PG1 11 60200270-60243137 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "dendritic cells: 1.4;Erythroid cells: 1.3;Kupffer cells: 3.4;Macrophages: 5.4;Microglial cells: 1.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 17.8" "Cell line enhanced" "Detected in many" "HMC-1: 8.1" HPA040075 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA040075: AB_10793915" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (9.42e-2)" "unprognostic (5.99e-2)" "unprognostic (1.45e-2)" "unprognostic (8.97e-2)" "unprognostic (1.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (4.16e-2)" "unprognostic (9.88e-3)" "unprognostic (4.97e-2)" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (4.05e-2)" 5.9 4.0 5.4 3.5 5.1 7.7 3.7 8.1 6.7 1.1 6.5 2.8 3.3 1.8 2.8 1.6 1.5 3.0 1.3 6.0 4.7 1.8 5.5 2.9 2.8 5.4 4.1 1.6 1.5 1.3 0.0 1.8 4.6 2.0 2.7 4.5 1.7 1.2 4.4 4.2 4.5 2.9 2.6 4.7 2.7 2.9 5.3 1.1 1.2 0.8 1.9 1.5 0.0 5.8 4.2 1.7 0.9 2.2 0.7 0.4 3.2 1.7 0.2 0.2 0.3 1.2 1.8 1.3 1.7 0.1 1.2 3.4 0.3 0.2 0.3 5.0 1.1 2.3 3.5 2.0 0.6 1.3 8.1 0.5 1.5 0.5 0.7 0.9 0.2 1.8 2.4 4.2 0.2 1.6 1.9 2.6 1.8 2.0 1.3 1.6 1.7 1.8 0.5 2.1 1.3 2.2 4.9 1.8 2.4 2.0 2.4 2.4 1.1 1.7 7.8 4.8 1.6 5.6 4.7 1.9 0.9 2.8 1.5 17.8 1.4 0.2 0.4 1.6 0.3 0.5 0.3 0.2 2.5 0.7 0.3 0.4 2.7 0.9 1.4 1.4 0.2 0.3 5.4 5.1 8.1 6.7 6.0 4.7 5.4 4.1 4.6 2.6 5.3 5.8 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 5.4 0.0 1.9 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058334-42070842 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 65.0;Hofbauer cells: 91.6;Kupffer cells: 64.4;monocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 202.5;intermediate monocyte: 249.1;myeloid DC: 195.2;non-classical monocyte: 257.9;plasmacytoid DC: 119.8" "Group enriched" "Detected in all" 6 "dendritic cells: 195.2;monocytes: 257.9" "Cell line enhanced" "Detected in all" "HMC-1: 190.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA000649: AB_1079448" "unprognostic (3.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (1.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (3.68e-2)" "unprognostic (1.92e-3)" "unprognostic (8.95e-2)" "unprognostic (2.53e-1)" 21.4 12.7 9.3 32.3 10.4 20.1 13.4 10.3 10.1 20.6 17.0 26.1 20.4 17.2 12.4 17.2 20.0 22.1 16.0 8.9 11.5 14.9 31.9 27.1 20.8 13.9 10.8 17.0 11.4 39.2 11.7 42.8 12.6 18.2 26.7 7.7 17.3 18.6 7.7 13.4 24.2 28.3 12.2 20.3 16.6 9.0 12.0 13.9 15.1 12.3 19.0 24.8 13.7 14.4 27.8 14.0 21.7 38.9 37.0 41.9 15.9 22.4 45.7 37.9 39.2 31.4 39.9 13.5 13.5 49.1 22.9 19.2 16.7 27.4 22.3 31.0 21.2 33.5 20.1 21.5 21.5 28.1 190.4 28.9 23.8 34.0 14.4 19.5 63.4 11.6 12.4 56.0 30.2 32.3 10.4 11.5 5.8 25.3 18.5 23.0 11.0 24.2 29.4 32.7 6.7 7.7 29.8 27.0 29.3 19.1 40.4 50.9 34.4 26.6 31.8 17.1 20.7 30.9 33.3 10.9 28.3 52.7 33.4 36.5 202.5 25.1 13.6 249.1 13.8 10.5 14.1 12.7 195.2 6.9 9.2 8.4 9.9 18.8 257.9 119.8 18.3 121.0 9.3 10.4 10.3 10.1 8.9 11.5 13.9 10.8 12.6 12.2 12.0 14.4 6.5 9.6 6.7 4.6 8.2 3.3 9.4 10.9 5.7 2.8 6.7 6.2 4.2 4.3 11.3 7.3 8.4 46.1 11.0 27.3 3.9 15.4 15.8 5.6 8.8 11.2 6.0 12.4 1.1 8.1 65.0 13.8 6.1 10.2 9.5 3.2 9.3 33.6 91.6 0.0 2.0 15.0 6.1 64.4 36.3 17.9 7.2 52.5 19.6 12.2 65.8 5.9 6.2 0.5 2.0 13.0 23.9 6.8 22.2 6.0 40.0 9.8 15.7 6.4 19.7 6.1 10.0 10.7 5.2 7.1 3.4 58.3 6.9 6.5 15.4 10.0 NAGK GNK ENSG00000124357 "N-acetylglucosamine kinase" Q9UJ70 2 71064344-71079808 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 216.9;Syncytiotrophoblasts: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 391.8;granulocytes: 288.7;monocytes: 594.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035206, HPA035207" Enhanced Approved Nucleoplasm,Cytosol NA NA 1000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol Nucleoplasm "HPA035206: AB_2674517, HPA035207: AB_10602031" "unprognostic (6.15e-2)" "unprognostic (4.23e-3)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.44e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.65e-3)" "unprognostic (2.18e-2)" "unprognostic (2.31e-1)" "unprognostic (9.99e-2)" "unprognostic (4.32e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.35e-4)" "unprognostic (8.60e-2)" "unprognostic (1.45e-2)" "unprognostic (5.50e-3)" "unprognostic (2.13e-2)" 41.2 36.0 47.0 61.2 48.0 21.9 35.1 49.5 52.1 57.5 47.0 37.7 21.0 33.6 40.6 156.2 29.0 44.1 31.4 46.9 52.9 35.1 42.8 39.6 79.6 50.9 50.4 31.0 42.2 80.7 42.3 44.3 53.7 30.0 34.2 16.5 75.0 37.9 26.6 63.0 33.6 50.1 48.3 88.9 33.9 50.2 49.0 60.8 27.4 32.3 98.4 71.7 59.7 52.1 55.9 39.2 22.6 25.8 114.2 67.5 98.3 119.0 65.5 95.6 86.8 54.3 29.5 30.3 29.3 107.4 113.5 25.7 22.4 43.9 62.7 44.9 16.4 17.0 12.6 37.5 91.6 10.5 37.7 60.7 49.6 101.8 16.4 68.3 107.7 31.7 8.1 34.8 143.4 52.2 28.6 40.2 28.7 53.5 38.4 22.1 64.2 15.8 65.5 91.4 25.1 13.0 35.2 62.1 45.1 50.7 30.4 13.9 66.0 99.0 37.8 36.9 44.8 23.0 24.8 18.0 69.6 31.5 54.5 86.6 594.1 245.1 36.9 526.5 39.2 102.5 44.2 37.0 391.8 103.7 36.7 30.0 288.7 65.3 378.2 318.5 54.7 466.2 47.0 48.0 49.5 52.1 46.9 52.9 50.9 50.4 53.7 48.3 49.0 52.1 22.9 38.5 34.2 15.0 48.6 26.9 28.4 60.8 19.4 46.1 27.4 27.6 18.0 17.2 56.9 38.6 22.9 146.0 67.4 13.9 41.1 66.1 151.3 22.5 26.1 31.7 23.4 12.8 11.5 45.7 144.0 35.6 15.8 24.9 51.9 31.1 30.0 12.9 216.9 47.1 15.2 20.4 28.5 121.8 67.5 33.0 30.1 106.0 39.2 26.2 118.6 45.4 17.5 17.1 24.0 59.1 32.3 37.6 51.2 15.5 23.3 64.7 35.2 55.6 19.7 31.8 37.4 68.0 25.6 39.9 41.6 318.8 29.1 32.2 16.2 34.7 NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 66.2;dendritic cells: 92.3;Hofbauer cells: 115.5;Kupffer cells: 175.1;Macrophages: 108.1;monocytes: 153.2;NK-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 112.4;HMC-1: 112.4;NB-4: 82.6;REH: 59.1;THP-1: 121.3;U-937: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Uncertain "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" 9.7 4.6 3.3 34.8 4.0 28.4 4.7 3.6 3.7 4.0 4.0 19.7 5.8 2.5 1.3 6.1 3.4 7.3 2.6 2.9 3.7 2.3 7.1 20.2 42.5 6.9 4.8 1.8 1.6 4.0 1.5 11.0 6.5 4.7 9.7 0.4 3.5 5.2 1.2 2.3 18.1 10.3 5.4 44.9 6.7 1.2 6.8 37.4 2.2 2.0 43.4 27.9 2.8 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.3 47.9 0.0 0.0 0.0 112.4 112.4 0.0 0.0 0.0 0.0 0.0 0.7 40.1 7.7 43.7 0.0 0.0 47.9 82.6 0.1 0.0 0.0 59.1 0.2 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 121.3 0.0 0.2 0.0 0.1 0.1 2.4 2.9 38.4 0.2 70.4 0.0 31.7 68.6 55.0 31.7 103.9 26.2 30.2 28.3 32.7 72.0 28.8 17.9 26.4 16.9 36.1 121.3 40.8 45.1 65.1 3.3 4.0 3.6 3.7 2.9 3.7 6.9 4.8 6.5 5.4 6.8 8.4 1.0 0.0 11.6 0.3 66.2 1.3 0.3 0.0 0.0 1.3 0.6 2.2 1.5 4.3 1.8 0.0 0.0 0.7 92.3 0.2 0.0 0.1 0.9 0.2 0.3 3.6 0.0 22.1 0.8 0.4 1.0 2.7 2.0 0.3 56.3 0.1 7.5 1.4 115.5 0.0 0.5 0.0 0.0 175.1 28.5 2.3 1.2 108.1 5.4 42.2 153.2 0.4 113.3 0.5 0.0 0.0 0.1 0.0 40.0 0.1 0.0 0.3 0.7 0.9 0.0 0.8 1.3 0.9 1.6 0.1 0.6 1.4 59.7 0.2 0.0 0.2 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122677 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 5.0;Exocrine glandular cells: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 6.8;K-562: 6.1;SCLC-21H: 6.1" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favorable (5.30e-4)" 1.2 1.4 2.0 0.8 2.3 1.1 2.0 1.5 2.6 0.8 0.8 1.5 1.4 0.8 2.6 1.1 1.4 0.6 1.8 2.4 1.9 0.8 4.1 1.2 0.6 2.5 1.8 1.4 1.8 1.2 1.2 0.5 2.7 1.2 1.3 2.0 2.3 1.0 2.6 3.8 1.9 0.8 1.6 1.1 1.3 0.7 2.0 1.0 1.6 1.5 0.8 0.9 0.8 3.6 2.6 1.5 0.6 0.0 1.3 1.2 0.0 2.6 0.8 0.9 0.5 0.1 2.1 0.0 6.8 1.9 0.2 3.0 0.0 1.7 0.7 0.1 0.9 0.4 1.0 0.1 2.0 0.0 1.7 2.1 2.5 1.0 0.9 0.6 2.1 0.0 6.1 0.1 2.1 2.8 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.1 1.4 2.8 6.1 0.1 5.3 4.3 1.6 0.6 3.1 1.7 0.4 0.2 1.3 1.8 0.1 0.1 0.0 0.1 0.1 0.0 2.6 0.5 4.4 0.4 0.6 4.9 0.8 2.3 1.1 0.5 4.7 1.3 1.5 1.0 0.3 1.6 2.3 0.6 1.3 1.8 2.0 2.3 1.5 2.6 2.4 1.9 2.5 1.8 2.7 1.6 2.0 3.6 0.8 0.0 2.2 0.3 0.2 1.9 1.4 1.4 1.8 0.4 1.5 2.0 0.9 1.5 2.3 0.0 0.0 0.4 0.0 0.2 0.0 2.9 0.0 0.6 1.3 0.3 3.5 5.0 1.0 3.7 0.0 0.8 1.5 0.5 1.3 0.8 0.4 1.1 1.2 0.0 0.7 0.3 0.0 0.8 0.6 0.0 0.6 1.5 1.8 1.0 0.5 1.1 0.0 1.5 1.2 2.0 0.3 0.0 0.0 0.2 0.6 1.2 0.8 1.0 0.0 0.3 0.8 0.2 0.2 1.3 1.8 0.4 0.1 1.1 0.5 0.5 NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "epididymis: 16783.1" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2034.2;Hofbauer cells: 2898.5;Kupffer cells: 2035.4" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 769.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 668.7;classical monocyte: 1300.7;intermediate monocyte: 1772.7;myeloid DC: 587.8;neutrophil: 674.2;non-classical monocyte: 1252.1;plasmacytoid DC: 2113.2" "Group enriched" "Detected in all" 5 "dendritic cells: 2113.2;granulocytes: 674.2;monocytes: 1772.7" "Cell line enhanced" "Detected in all" "ASC diff: 1619.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" NA NA 53000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032888: AB_2157036, HPA000835: AB_1079499" "unprognostic (1.27e-3)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (6.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.97e-1)" "prognostic favorable (6.55e-4)" "unprognostic (1.42e-1)" 260.1 297.0 127.1 261.3 145.4 305.3 221.3 152.2 190.6 284.5 434.0 259.7 201.7 196.7 16783.1 185.0 170.0 356.0 215.1 118.1 156.9 322.4 202.4 786.0 360.3 185.7 145.6 283.1 219.9 241.3 197.5 263.1 179.2 164.2 220.8 48.6 221.9 261.3 58.7 181.6 193.3 180.5 151.1 305.6 206.8 156.8 172.1 134.4 444.7 114.7 241.9 347.4 187.9 195.5 297.2 199.3 124.8 179.4 1619.3 498.6 404.8 194.1 707.1 200.9 398.9 351.7 420.3 78.6 141.6 181.9 372.6 595.9 170.0 405.5 188.6 120.4 126.3 29.6 96.7 296.2 348.6 51.0 548.4 467.7 388.9 173.7 336.9 930.2 298.1 87.0 32.9 601.4 224.0 106.9 70.1 75.9 52.9 489.0 307.9 39.5 219.1 281.6 511.1 735.0 5.5 91.3 296.3 120.3 298.0 359.6 205.2 225.7 268.9 291.9 342.0 396.1 188.2 253.7 452.5 24.2 292.1 168.4 163.4 668.7 1300.7 274.1 92.2 1772.7 87.9 295.2 126.5 92.3 587.8 241.8 120.9 100.5 674.2 99.5 1252.1 2113.2 187.8 1304.5 127.1 145.4 152.2 190.6 118.1 156.9 185.7 145.6 179.2 151.1 172.1 195.5 154.9 381.4 2034.2 11.1 160.2 374.9 557.8 1074.2 170.2 9.9 138.6 220.5 55.4 163.0 626.9 331.1 22.9 228.3 664.0 301.0 305.2 500.4 90.9 123.8 168.5 276.5 119.7 65.4 2.1 279.4 803.3 318.1 61.7 161.0 341.4 104.2 447.3 195.6 2898.5 8.4 3.8 264.8 832.1 2035.4 750.9 69.6 566.7 1462.6 602.9 6.5 790.5 167.4 117.4 7.5 24.4 368.3 405.1 291.9 287.4 357.9 298.1 969.0 393.3 25.1 131.5 118.3 155.9 268.1 166.7 182.6 320.7 210.4 109.9 330.0 298.5 521.6 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NSMAF "FAN, GRAMD5" ENSG00000035681 "Neutral sphingomyelinase activation associated factor" Q92636 8 58583508-58659853 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 89.7;Inhibitory neurons: 94.9;Oligodendrocyte precursor cells: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023067, HPA023148, HPA023151" Uncertain Approved Nucleoli NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 3: T-cells - Adaptive immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoli "HPA023067: AB_1854653, HPA023148: AB_10670028, HPA023151: AB_1854654" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.75e-1)" "unprognostic (8.86e-3)" "unprognostic (2.69e-1)" "unprognostic (8.73e-2)" "unprognostic (2.96e-3)" "unprognostic (9.03e-2)" "unprognostic (2.29e-1)" "unprognostic (8.11e-2)" "unprognostic (1.52e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (4.61e-9)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (2.38e-1)" "unprognostic (1.69e-1)" 16.8 14.9 8.5 16.1 9.5 7.9 13.5 9.0 9.8 14.2 9.7 15.7 9.3 13.9 9.1 13.1 10.8 10.7 11.9 8.4 9.1 9.4 5.7 12.0 21.6 9.3 9.0 12.1 17.1 17.5 10.4 13.4 9.2 12.1 14.5 4.8 11.3 12.5 18.5 19.2 14.8 14.1 8.7 16.8 14.0 5.5 10.5 35.8 13.5 15.4 22.2 16.2 13.3 10.0 33.7 32.7 14.3 20.1 53.8 43.3 24.8 26.8 58.5 36.3 33.9 17.8 20.6 40.5 21.6 41.6 37.6 26.6 24.7 21.2 41.3 46.0 13.7 75.7 19.8 20.5 67.8 33.7 51.1 29.2 33.7 26.2 99.5 29.6 36.5 36.9 32.9 29.1 41.6 25.7 71.5 26.6 25.7 27.0 12.6 26.7 21.2 11.6 19.8 26.4 13.1 16.5 22.4 8.3 24.8 18.6 20.1 41.8 34.4 35.7 21.7 48.2 27.3 5.5 2.6 31.6 52.3 25.6 23.1 8.3 7.1 4.7 6.0 5.0 6.2 4.2 6.4 6.5 14.0 4.0 4.4 4.3 14.6 6.4 3.6 4.7 8.6 4.7 8.5 9.5 9.0 9.8 8.4 9.1 9.3 9.0 9.2 8.7 10.5 10.0 9.6 9.6 5.9 68.9 28.4 18.4 10.4 7.2 26.2 9.7 7.8 6.9 15.8 1.5 9.6 9.2 4.2 12.1 17.4 8.9 3.9 7.7 0.3 5.9 14.5 12.1 14.4 12.2 89.7 8.8 8.3 13.8 14.8 7.8 28.5 15.8 5.3 4.0 17.8 32.0 94.9 10.4 2.0 31.0 35.3 2.1 16.4 33.9 10.6 54.4 22.6 6.3 13.4 102.1 51.2 7.4 9.1 12.8 18.3 13.0 8.0 4.9 3.8 6.3 6.6 18.0 10.8 2.0 3.5 16.1 17.8 9.3 22.7 10.6 10.7 11.0 OCSTAMP "C20orf123, dJ257E24.3" ENSG00000149635 "Osteoclast stimulatory transmembrane protein" Q9BR26 20 46540946-46550654 "Predicted membrane proteins, Transporters" Differentiation "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Langerhans cells: 1.9;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.1;HMC-1: 2.2;Karpas-707: 1.3;NB-4: 2.5;RPMI-8226: 1.2;U-266/84: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA031116 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA031116: AB_10600758" "unprognostic (2.77e-1)" "unprognostic (3.04e-1)" "unprognostic (8.80e-2)" "unprognostic (5.02e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "unprognostic (9.59e-2)" "unprognostic (2.08e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OGFRL1 dJ331H24.1 ENSG00000119900 "Opioid growth factor receptor like 1" Q5TC84 6 71288811-71309059 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.6" "Cell type enhanced" "Detected in many" "Astrocytes: 175.3;Langerhans cells: 144.0;Macrophages: 155.7;monocytes: 133.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027122 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Nucleoplasm "HPA027122: AB_2156775" "unprognostic (8.44e-3)" "unprognostic (1.41e-2)" "unprognostic (2.48e-1)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (4.24e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (9.62e-3)" "unprognostic (2.30e-2)" "unprognostic (2.49e-1)" "unprognostic (4.22e-2)" "unprognostic (2.11e-1)" "unprognostic (1.39e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (3.25e-2)" "unprognostic (5.58e-3)" 25.2 11.2 32.9 16.1 28.1 26.7 51.0 40.5 26.3 7.9 7.8 9.3 3.6 10.4 13.7 33.2 6.5 10.8 6.8 40.9 47.7 7.1 6.4 11.5 14.5 50.8 60.5 6.6 8.0 6.2 7.6 13.5 51.5 8.4 5.3 13.2 46.3 12.8 5.1 20.1 6.8 33.4 55.3 16.8 6.3 2.8 47.9 11.4 5.3 12.1 25.5 7.4 12.5 69.6 9.7 2.9 10.0 0.0 26.5 24.1 3.6 42.2 26.5 16.9 17.0 3.7 1.8 59.1 56.3 18.5 15.6 4.7 7.8 29.4 59.5 12.5 6.1 13.0 10.0 1.5 21.4 6.2 4.4 24.4 24.7 12.5 38.8 14.2 13.7 0.0 0.8 4.5 58.8 8.1 0.0 9.7 4.0 3.8 2.3 4.2 30.4 13.8 38.8 0.7 33.8 15.3 12.6 7.8 2.8 14.3 13.4 48.0 21.1 41.3 20.5 4.3 14.1 6.0 0.4 7.6 13.8 41.0 7.2 3.4 2.6 0.1 0.4 1.7 0.4 0.3 0.3 0.4 2.1 0.5 0.0 0.3 11.1 0.5 1.3 0.8 0.1 0.6 32.9 28.1 40.5 26.3 40.9 47.7 50.8 60.5 51.5 55.3 47.9 69.6 40.3 6.4 18.6 175.3 17.4 38.9 22.3 18.4 22.8 42.8 79.4 86.4 8.7 11.5 14.1 11.0 25.0 23.2 31.7 1.4 1.9 17.0 0.5 8.0 14.2 30.2 14.4 11.1 29.1 32.9 11.0 50.8 5.6 19.1 6.3 6.6 8.9 5.1 61.7 38.7 28.0 2.2 8.2 95.5 144.0 1.2 16.4 155.7 32.0 71.2 133.5 87.0 18.6 13.0 4.0 19.3 2.4 33.1 11.6 16.2 0.1 4.9 3.2 6.0 26.3 26.8 31.3 0.6 1.2 57.9 46.5 19.0 19.3 3.4 4.4 19.3 OR5AN1 ENSG00000176495 "Olfactory receptor family 5 subfamily AN member 1" Q8NGI8 11 59358895-59371714 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Macrophages - Innate immune response" 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.3 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 77.3;Hofbauer cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 94.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA015022: AB_1854807" "unprognostic (1.17e-1)" "unprognostic (3.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.15e-2)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (8.60e-2)" "unprognostic (8.54e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-3)" "unprognostic (1.77e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (2.30e-2)" "unprognostic (4.46e-2)" "unprognostic (6.43e-3)" "unprognostic (9.17e-3)" 17.3 34.1 18.0 8.2 16.5 17.6 15.2 16.9 17.1 24.4 26.0 22.7 9.2 18.3 16.3 15.4 19.2 9.9 16.7 15.3 16.3 19.3 70.2 14.2 11.9 18.6 18.5 18.9 17.7 18.9 18.0 14.9 17.1 26.3 8.6 4.0 14.6 17.0 7.9 14.3 16.1 9.8 17.4 22.5 17.1 15.6 20.5 11.2 16.4 8.1 10.6 27.2 20.2 17.7 2.8 15.8 8.1 10.7 68.1 60.7 0.6 9.3 62.3 6.8 17.2 1.5 26.1 3.9 20.7 17.9 27.5 12.7 1.4 17.6 4.6 12.3 5.2 10.2 4.9 16.1 94.9 11.2 30.5 65.5 45.9 13.1 25.5 63.8 11.7 2.2 11.7 20.6 22.1 10.8 0.7 42.6 6.6 9.1 4.3 8.6 6.3 30.8 26.2 6.8 2.0 13.5 8.4 2.6 14.9 19.5 19.7 45.5 8.5 5.1 3.5 11.4 2.2 50.4 4.0 3.1 25.3 26.4 7.9 23.2 8.7 26.6 3.4 9.2 3.6 7.1 1.8 2.7 8.5 6.7 2.2 2.9 15.3 11.7 12.6 9.5 2.7 3.3 18.0 16.5 16.9 17.1 15.3 16.3 18.6 18.5 17.1 17.4 20.5 17.7 12.1 6.4 10.8 0.0 23.9 7.9 24.5 25.6 32.5 1.5 11.1 19.6 6.9 5.7 11.6 16.5 2.1 28.1 25.9 11.1 13.7 21.4 61.1 16.5 21.8 16.5 15.0 16.2 0.0 11.4 2.7 25.9 4.1 10.5 7.0 17.9 23.6 77.3 93.8 35.3 0.0 11.3 10.2 43.7 11.5 36.7 53.1 31.4 21.4 0.0 39.1 24.4 17.5 0.0 0.0 9.5 18.4 43.2 18.1 14.0 9.5 48.2 14.7 3.6 26.3 11.0 14.0 26.5 2.5 17.0 4.5 4.4 9.7 61.0 5.8 20.4 OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108041409-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 210000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Vesicles" "HPA010851: AB_1079533" "prognostic unfavorable (4.36e-4)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (1.72e-3)" "prognostic unfavorable (4.26e-4)" "unprognostic (9.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.34e-6)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" 26.1 19.1 4.7 17.9 5.2 5.7 9.8 5.1 5.8 10.4 33.1 12.2 7.9 13.7 9.0 12.7 9.5 12.5 19.2 5.3 9.2 15.6 13.1 16.2 14.7 6.0 7.6 7.5 5.8 15.3 8.3 14.1 7.9 13.8 11.1 17.6 8.9 16.7 11.8 9.8 9.0 23.3 5.3 18.3 8.5 10.1 7.4 13.7 10.7 11.5 13.5 16.9 7.0 8.3 6.0 17.2 20.1 29.4 59.0 19.0 28.6 42.8 42.7 30.7 50.4 10.0 9.8 13.7 34.4 30.0 82.5 11.1 20.2 14.6 47.0 31.6 15.7 28.9 10.9 12.8 45.6 32.1 64.6 28.1 35.7 37.7 30.0 28.2 15.8 15.2 23.3 48.7 50.3 8.4 7.1 7.3 8.0 7.1 13.0 11.4 29.1 7.5 22.0 15.7 2.2 11.8 34.7 8.7 79.9 26.6 10.0 45.8 19.3 26.7 9.8 59.7 61.4 18.6 34.4 11.9 78.9 21.3 60.3 31.4 20.2 22.8 20.3 29.4 21.5 14.7 16.9 22.3 17.8 8.6 15.6 19.8 29.8 22.0 43.5 12.9 22.6 27.0 4.7 5.2 5.1 5.8 5.3 9.2 6.0 7.6 7.9 5.3 7.4 8.3 28.5 9.6 19.0 26.4 26.0 46.7 19.8 11.7 21.6 28.3 10.0 7.0 24.8 12.8 9.4 12.9 10.4 21.7 32.3 21.9 1.9 12.4 12.0 7.5 15.7 20.7 4.2 4.6 36.6 22.9 33.9 24.4 15.8 9.6 24.1 6.9 26.7 13.2 52.8 28.6 40.1 5.8 6.1 46.5 29.5 5.4 14.3 43.1 151.2 20.6 25.6 23.7 40.2 21.1 36.6 16.8 17.0 28.6 25.0 17.9 7.6 25.5 9.8 17.5 26.3 18.5 29.6 28.0 18.7 12.4 31.1 61.2 29.5 23.7 3.3 16.0 OTOA "CT108, DFNB22" ENSG00000155719 Otoancorin Q7RTW8 16 21663968-21761935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 1.8;testis: 4.0" "Cell type enhanced" "Detected in some" "Hofbauer cells: 111.8;Kupffer cells: 60.5;Late spermatids: 18.7;Macrophages: 34.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041405 Enhanced "Secreted in other tissues" NA NA 51000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Macrophages - Innate immune response" "HPA041405: AB_10796344" "unprognostic (7.96e-2)" "unprognostic (2.44e-4)" "unprognostic (1.66e-2)" "unprognostic (9.69e-2)" "unprognostic (2.15e-1)" "unprognostic (1.35e-1)" "unprognostic (5.11e-1)" "unprognostic (4.71e-2)" "unprognostic (7.92e-2)" "unprognostic (3.58e-1)" "unprognostic (1.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.08e-4)" "unprognostic (1.83e-1)" "unprognostic (1.20e-1)" "unprognostic (2.24e-1)" "unprognostic (2.18e-2)" 0.1 0.2 0.2 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 4.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 8.4 0.0 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.0 1.8 0.0 0.4 0.1 0.3 0.0 0.2 11.6 0.3 0.2 1.0 1.2 0.0 2.6 0.4 0.8 0.3 0.0 0.5 5.7 0.1 0.7 0.4 111.8 0.0 1.8 0.1 0.0 60.5 3.7 18.7 0.3 34.4 1.8 0.0 1.9 0.0 0.0 0.5 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.7 0.0 0.0 6.6 0.2 0.7 9.4 7.4 0.0 0.1 0.5 0.2 0.1 0.2 0.2 PEAK3 "C19orf35, FLJ45778" ENSG00000188305 "PEAK family member 3" Q6ZS72 19 2274631-2282175 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 4.1" "Cell type enhanced" "Detected in some" "dendritic cells: 1.5;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 41.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 41.0" "Cell line enriched" "Detected in some" 9 "HMC-1: 12.2" "Group enriched" "Detected in some" 5 "basal ganglia: 6.7;cerebellum: 3.1" HPA057806 Uncertain Uncertain Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA057806: AB_2683534" "unprognostic (9.42e-2)" "unprognostic (3.26e-2)" "unprognostic (7.27e-2)" "unprognostic (6.23e-2)" "unprognostic (2.65e-2)" "unprognostic (8.40e-3)" "unprognostic (3.67e-1)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (2.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (1.90e-1)" 0.5 0.4 0.5 1.3 0.9 2.3 0.3 0.5 1.6 0.2 0.1 0.4 0.2 0.2 0.0 0.2 0.5 0.2 0.7 0.4 0.5 0.3 0.2 1.1 0.4 1.4 1.0 0.1 0.2 0.0 0.2 0.1 1.0 0.3 0.2 0.0 0.2 0.0 0.3 0.3 0.8 0.1 0.9 4.1 0.3 0.1 0.8 0.1 0.2 0.0 0.3 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.4 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 10.5 4.4 11.7 1.6 5.7 0.2 0.2 0.1 0.2 1.8 0.4 0.1 0.3 41.0 4.5 1.9 0.2 0.0 1.1 0.5 0.9 0.5 1.6 0.4 0.5 1.4 1.0 1.0 0.9 0.8 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 12.0 25.7 15.5 10.0 15.1 24.1 9.3 15.1 18.9 12.6 13.4 10.7 9.8 12.7 13.0 20.7 9.6 14.0 14.2 15.5 17.8 12.6 15.0 14.2 11.2 20.2 18.8 10.0 8.4 16.6 15.8 18.0 22.0 10.9 8.7 12.9 10.5 10.4 12.7 17.4 10.8 13.0 15.8 14.6 9.4 10.8 17.3 9.8 9.5 13.0 10.6 14.5 12.7 15.2 28.7 21.3 17.2 30.7 36.0 25.8 13.8 28.0 61.5 43.3 45.7 19.4 27.7 10.4 16.2 35.8 31.8 27.1 19.3 55.9 35.8 12.6 16.4 9.3 14.6 17.7 34.5 8.4 12.7 27.3 46.9 45.4 80.1 47.4 22.4 19.9 14.7 16.5 30.4 14.6 18.4 6.4 11.1 14.7 19.8 8.6 17.8 10.3 29.7 26.6 5.8 18.9 23.9 5.9 35.5 24.0 16.4 13.2 25.0 20.6 15.2 24.6 22.1 14.6 18.4 16.9 38.1 5.0 6.8 0.0 1.2 0.0 1.3 0.8 1.0 1.4 0.5 1.1 1.3 0.6 0.4 0.9 0.4 0.7 0.6 0.6 1.2 0.6 15.5 15.1 15.1 18.9 15.5 17.8 20.2 18.8 22.0 15.8 17.3 15.2 4.9 3.2 5.4 9.8 12.0 13.4 4.5 6.5 8.0 14.7 10.7 8.9 10.4 10.0 4.3 5.5 12.5 14.0 12.5 8.6 3.9 4.9 2.4 6.8 15.4 6.9 3.0 8.2 10.9 4.9 6.4 12.0 7.1 7.6 1.3 5.7 3.6 9.9 38.1 11.8 10.9 4.0 6.1 15.0 24.7 2.2 4.4 19.0 10.6 12.2 15.0 8.0 18.6 5.5 6.0 7.2 0.8 9.1 9.4 5.8 9.0 7.3 4.8 15.1 6.6 11.9 8.0 11.0 6.1 6.3 14.3 27.1 9.7 12.4 3.6 7.8 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.2;placenta: 23.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.2;Macrophages: 140.9" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 49 "dendritic cells: 14.1;monocytes: 43.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;PC-3: 3.4;RT4: 1.6;U-2 OS: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 290000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 4.5 3.1 1.6 22.9 3.6 2.8 2.6 2.7 4.5 2.5 0.4 7.5 4.1 4.8 1.1 0.6 1.9 6.0 0.6 2.6 1.4 0.3 6.9 7.2 26.8 3.9 2.6 1.1 0.8 21.0 2.1 23.3 4.2 13.1 10.3 0.6 1.4 2.6 0.4 3.6 3.3 2.8 2.6 27.2 2.9 0.9 8.9 4.9 20.2 0.0 10.0 11.1 0.3 7.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.7 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 3.4 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.3 43.4 0.3 0.1 9.2 0.3 0.3 0.0 0.0 14.1 0.0 0.0 0.1 0.5 0.0 0.5 0.3 0.0 11.9 1.6 3.6 2.7 4.5 2.6 1.4 3.9 2.6 4.2 2.6 8.9 7.4 0.5 0.0 1.3 0.3 3.6 0.8 4.4 0.0 0.0 0.2 0.3 4.3 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.6 0.1 1.6 50.3 0.6 3.5 0.0 7.1 0.0 5.1 1.8 0.0 1.5 0.0 0.0 0.0 0.0 372.2 1.7 4.8 0.3 0.0 24.6 4.9 0.1 0.0 140.9 10.6 11.2 29.3 0.3 0.0 6.0 0.3 0.3 0.0 0.0 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.9 0.6 0.1 0.0 0.1 0.1 3.1 0.8 8.9 0.2 3.8 PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40380439 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 711.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 688.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 1727.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 1727.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 450000 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favorable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" 169.3 200.0 143.3 78.4 159.7 48.3 138.4 46.0 229.7 139.4 54.0 131.4 71.7 155.7 84.7 84.9 133.5 96.7 206.1 202.5 294.4 130.2 121.3 181.5 98.1 132.4 128.5 199.0 151.0 105.9 711.9 123.4 137.9 133.4 49.2 51.4 138.7 106.2 105.1 120.5 105.3 79.1 63.8 197.0 126.5 77.7 197.7 44.3 120.8 82.3 41.4 126.2 126.0 129.6 85.6 257.8 163.7 259.1 444.2 210.2 124.5 206.5 208.6 146.4 166.6 49.4 93.8 36.9 211.0 180.9 47.8 39.3 39.9 81.2 63.5 138.4 145.3 39.9 82.1 63.2 302.7 16.8 435.1 402.5 167.0 112.1 76.6 244.2 125.0 59.3 142.5 144.5 106.7 111.5 29.5 79.6 107.4 138.7 52.8 37.0 124.5 154.2 75.2 63.2 116.7 193.9 99.0 60.6 113.8 169.5 83.6 283.2 222.3 122.8 58.5 105.6 47.0 148.9 173.3 38.8 197.7 66.2 77.9 1727.4 256.7 378.7 75.0 129.5 62.0 34.4 59.5 67.7 235.0 28.1 60.8 61.3 25.7 102.3 64.2 34.7 64.5 208.6 143.3 159.7 46.0 229.7 202.5 294.4 132.4 128.5 137.9 63.8 197.7 129.6 66.7 32.1 69.6 59.4 27.0 35.4 93.6 263.1 39.9 101.5 45.9 61.2 22.0 45.8 90.4 57.0 33.3 158.2 27.2 42.5 21.5 52.5 8.7 32.0 49.8 53.9 72.8 18.7 99.1 58.3 107.2 158.8 38.2 31.5 60.3 134.7 88.2 43.1 688.4 121.1 113.4 41.3 126.1 280.9 59.1 15.7 151.6 261.3 92.5 50.6 54.2 94.1 35.0 53.3 70.2 54.3 42.6 143.7 85.8 57.9 78.8 37.1 35.2 47.6 19.7 73.1 59.7 24.2 67.9 32.4 33.4 195.9 28.8 114.1 41.6 68.2 PLEKHM2 KIAA0842 ENSG00000116786 "Pleckstrin homology and RUN domain containing M2" Q8IWE5 1 15684320-15734769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032304 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA032304: AB_10670964" "unprognostic (3.07e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.36e-8)" "unprognostic (4.01e-2)" "unprognostic (1.60e-1)" "unprognostic (1.10e-3)" "unprognostic (1.03e-2)" "unprognostic (2.59e-1)" "unprognostic (6.73e-3)" "unprognostic (3.30e-1)" "unprognostic (5.50e-1)" "unprognostic (6.49e-2)" "unprognostic (1.89e-2)" 40.2 37.7 72.3 23.0 76.1 66.2 32.3 63.5 121.9 33.4 44.6 32.4 16.3 32.0 7.6 40.5 27.0 22.0 61.3 78.4 57.2 26.3 20.6 46.9 26.4 65.3 63.3 33.3 27.7 24.6 26.8 22.8 63.8 29.5 9.0 8.2 27.2 15.2 136.0 47.6 27.8 17.1 60.0 42.9 28.3 35.6 70.6 18.9 28.2 62.9 17.4 32.3 34.6 85.9 43.1 25.5 24.4 42.7 56.8 45.3 26.5 36.3 58.9 45.1 41.4 35.0 37.7 23.9 37.8 55.8 45.6 25.2 19.0 40.9 17.2 46.4 33.2 29.5 43.3 27.3 59.9 25.0 32.5 52.2 45.2 47.0 53.2 51.9 34.2 39.6 35.8 63.0 23.3 33.5 28.5 25.9 18.6 14.4 21.1 38.7 21.3 32.3 22.1 18.7 25.3 34.5 40.7 24.1 99.1 16.6 16.3 37.8 38.8 62.3 29.0 62.7 27.5 31.9 23.2 29.7 53.7 39.7 38.7 0.3 2.8 1.8 1.8 2.8 1.4 2.1 1.2 0.7 2.6 2.4 1.5 1.2 3.0 1.1 3.3 2.1 0.8 1.5 72.3 76.1 63.5 121.9 78.4 57.2 65.3 63.3 63.8 60.0 70.6 85.9 25.6 16.0 16.0 28.7 15.5 24.9 11.7 8.8 3.4 28.4 14.2 14.2 26.6 8.6 7.8 16.5 22.9 7.8 16.8 16.6 1.9 13.1 31.6 15.1 26.1 18.9 11.3 2.5 27.2 17.8 8.9 23.3 14.3 25.7 18.4 25.5 26.7 11.6 37.2 28.6 25.8 15.4 6.1 38.9 20.9 24.5 20.5 36.9 8.8 23.4 14.5 28.4 3.1 16.6 17.6 23.4 14.7 18.0 8.7 19.2 10.5 6.8 8.9 21.1 0.0 27.4 18.7 18.4 6.0 15.9 36.1 24.6 11.8 26.1 12.2 23.9 PLEKHO2 "DKFZp761K2312, PLEKHQ1, PP1628, pp9099" ENSG00000241839 "Pleckstrin homology domain containing O2" Q8TD55 15 64841883-64868002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 103.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 63.2;Kupffer cells: 52.3;Macrophages: 46.5;Muller glia cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 27.1;granulocytes: 77.3;monocytes: 73.0" "Cell line enhanced" "Detected in many" "ASC diff: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040055 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 200000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA040055: AB_10793954" "unprognostic (4.32e-2)" "unprognostic (7.32e-3)" "unprognostic (8.60e-2)" "unprognostic (9.10e-2)" "unprognostic (1.11e-1)" "unprognostic (2.90e-2)" "unprognostic (3.05e-2)" "unprognostic (2.80e-1)" "unprognostic (7.70e-2)" "unprognostic (2.05e-2)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.08e-3)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (1.78e-1)" "unprognostic (5.85e-3)" 37.9 31.8 23.1 30.5 26.9 52.0 22.7 25.0 25.0 17.0 16.7 23.6 10.0 19.8 5.7 13.9 22.4 26.0 16.5 21.7 24.4 14.2 11.8 42.2 34.3 31.8 26.2 14.9 8.2 7.4 10.3 25.4 26.6 17.4 7.8 14.4 9.9 13.9 5.8 10.6 17.8 22.9 27.6 103.2 16.3 8.3 28.0 16.0 29.9 8.2 21.1 25.8 16.7 25.5 6.5 4.2 7.9 7.8 68.0 38.8 18.4 18.5 27.4 19.2 19.6 5.1 4.0 17.1 9.5 37.7 19.5 2.2 9.0 7.4 11.2 26.6 2.7 17.2 1.9 6.0 52.2 19.4 24.7 28.3 6.5 24.0 7.8 16.6 27.0 3.5 5.2 59.5 25.9 1.9 4.1 20.9 15.0 3.2 3.7 14.9 19.0 12.2 3.1 4.4 0.6 6.7 7.7 2.6 25.4 12.9 2.7 26.1 35.3 14.8 13.4 14.1 7.8 22.0 37.1 5.8 16.0 24.8 8.8 22.2 43.2 25.6 13.2 52.3 11.9 9.8 7.4 12.2 27.1 6.8 3.1 6.5 77.3 7.0 73.0 3.1 10.7 36.0 23.1 26.9 25.0 25.0 21.7 24.4 31.8 26.2 26.6 27.6 28.0 25.5 24.9 0.0 5.6 17.3 9.1 5.6 2.3 2.3 0.6 0.6 6.4 8.3 3.6 2.8 2.4 9.2 0.0 4.2 15.9 0.5 3.9 2.4 5.0 1.4 5.9 26.1 0.0 2.1 0.2 1.5 5.9 8.6 0.5 2.3 18.4 2.5 34.2 2.1 63.2 0.0 0.2 0.3 4.1 52.3 24.3 2.9 18.3 46.5 14.2 8.4 18.9 56.8 16.5 2.5 2.7 2.0 0.0 25.6 2.7 3.5 0.0 2.2 2.1 3.8 13.1 10.2 5.9 0.9 2.3 1.9 4.4 6.0 10.5 4.6 0.4 3.4 PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 1640.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 220.8;BEWO: 186.8;HHSteC: 233.2;HSkMC: 302.2;U-87 MG: 326.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" 437.9 188.9 107.9 80.5 109.8 20.7 122.6 100.8 142.0 155.4 197.6 76.9 41.6 114.9 72.6 62.0 173.5 182.3 123.4 100.4 119.0 198.9 29.5 97.1 61.3 119.5 152.2 159.5 296.9 22.1 38.5 428.8 126.0 50.7 42.4 4.8 132.1 71.5 24.0 68.0 71.6 181.9 124.7 57.6 89.7 32.3 114.5 229.9 44.4 20.8 21.1 339.7 113.1 118.1 13.8 1.9 94.9 0.1 220.8 66.8 186.8 5.3 16.3 18.5 11.0 78.7 15.9 3.5 151.6 23.6 0.4 154.7 29.2 0.6 8.4 1.8 0.2 28.8 3.3 37.7 233.2 0.0 35.5 302.2 7.7 49.1 0.9 74.1 41.3 3.2 9.5 44.9 6.2 3.9 3.2 123.1 16.9 12.5 74.5 1.3 0.1 1.7 0.5 0.0 10.1 35.4 3.7 110.3 160.9 15.7 1.5 117.2 9.0 46.2 1.1 24.2 0.8 19.7 5.3 5.4 326.4 34.3 7.8 33.1 2.7 29.7 1.6 7.1 1.2 8.7 0.4 1.6 2.5 3.2 0.0 1.0 1.4 4.9 12.6 17.5 0.8 2.7 107.9 109.8 100.8 142.0 100.4 119.0 119.5 152.2 126.0 124.7 114.5 118.1 21.9 0.0 2.3 30.3 3.8 40.7 34.9 53.0 33.0 0.4 9.5 22.6 1.5 5.7 9.6 27.6 0.0 14.8 3.5 0.5 1.9 3.4 16.3 54.6 36.9 27.9 0.0 9.0 0.8 103.2 97.7 256.8 3.6 5.7 0.0 23.4 121.1 2.8 1640.3 3.3 1.4 1.2 12.2 254.0 40.9 24.9 307.9 71.8 35.6 4.7 3.8 13.8 7.2 0.5 0.2 9.9 0.0 199.0 11.8 15.7 0.0 18.2 70.8 1.1 32.9 16.1 35.6 5.7 7.3 24.0 35.8 31.7 3.3 99.5 0.7 18.4 PLXND1 KIAA0620 ENSG00000004399 "Plexin D1" Q9Y4D7 3 129555214-129606676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Endothelial cells: 102.1;Hepatic stellate cells: 132.1;Hofbauer cells: 81.5;Kupffer cells: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 10.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 392.3;HSkMC: 286.1;HUVEC TERT2: 346.1;TIME: 414.4" "Group enriched" "Detected in all" 4 "amygdala: 36.6;basal ganglia: 33.1;cerebral cortex: 27.4;hippocampal formation: 26.3" "Low region specificity" "Detected in all" CAB020819 Approved NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB020819: " "unprognostic (8.97e-3)" "unprognostic (1.95e-1)" "unprognostic (6.30e-2)" "unprognostic (8.35e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-3)" "unprognostic (6.35e-2)" "unprognostic (4.51e-2)" "unprognostic (3.69e-1)" "unprognostic (3.02e-3)" "unprognostic (3.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.93e-7)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (3.17e-2)" "unprognostic (1.00e-2)" 72.6 22.1 32.0 37.4 38.1 26.5 47.4 36.2 35.6 58.4 26.1 19.5 6.0 33.5 17.6 21.5 35.0 39.4 39.8 29.3 34.2 24.7 18.3 67.5 34.7 48.7 43.5 16.3 13.9 18.0 11.1 112.4 43.8 19.0 16.9 3.5 13.3 27.0 12.9 19.5 20.9 52.6 38.8 33.6 15.8 10.8 49.0 62.7 29.5 39.8 23.2 37.1 26.8 43.2 10.0 57.7 47.4 16.3 392.3 167.9 98.4 42.8 123.1 25.5 29.5 13.4 8.1 2.1 179.9 152.9 13.2 0.6 25.9 0.6 7.5 1.9 3.2 40.7 30.2 61.4 44.8 13.5 11.0 286.1 1.7 26.4 2.8 36.6 346.1 2.1 14.5 1.5 34.8 31.0 2.4 44.2 11.8 2.4 8.0 47.4 32.0 51.8 10.2 2.3 27.6 1.1 11.0 3.5 15.9 107.6 15.5 59.7 414.4 21.5 28.5 0.6 32.4 1.9 2.2 19.9 7.5 29.2 19.0 0.0 10.7 0.0 1.7 5.1 6.8 0.0 1.2 1.4 2.9 0.0 0.0 0.1 0.2 3.1 5.2 3.6 0.0 1.7 32.0 38.1 36.2 35.6 29.3 34.2 48.7 43.5 43.8 38.8 49.0 43.2 107.3 3.2 27.2 12.4 3.6 8.0 0.4 2.1 0.6 0.1 7.6 3.4 10.6 5.7 3.1 0.0 0.0 7.1 16.9 0.2 0.0 1.4 1.4 3.7 52.5 102.1 13.1 12.6 10.4 3.5 16.4 19.5 5.6 6.2 22.2 1.3 132.1 7.7 81.5 0.0 0.6 3.2 6.1 75.6 31.8 1.8 38.8 41.7 8.8 27.2 29.4 6.5 10.3 0.5 27.7 2.7 0.1 13.9 12.9 0.5 0.0 0.3 1.2 0.3 32.9 14.4 37.1 0.6 4.0 1.5 4.4 5.3 14.4 49.5 0.5 0.6 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 251.9;Kupffer cells: 315.8;Langerhans cells: 328.8;Macrophages: 271.3;monocytes: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.3;eosinophil: 624.2;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 683.9;non-classical monocyte: 815.7" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 683.9;monocytes: 1254.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 1082.7;THP-1: 1449.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 240000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 69.8 59.4 92.9 92.7 95.6 117.5 95.7 100.4 135.9 70.1 106.1 50.5 32.1 72.7 60.1 45.1 55.4 57.1 45.3 93.6 101.2 75.8 54.1 128.5 93.9 97.0 96.7 68.6 42.6 79.2 39.0 74.8 99.6 73.4 58.8 89.4 56.8 63.2 21.3 40.3 39.2 95.3 101.6 177.0 45.1 37.6 99.1 78.0 60.0 37.1 75.1 79.1 34.7 113.5 115.6 62.5 93.7 81.0 106.5 92.1 209.8 68.4 127.9 153.0 183.3 350.1 270.5 140.1 118.1 65.2 112.2 209.5 154.9 112.7 163.6 186.4 151.4 100.3 127.2 155.5 137.5 233.7 158.9 103.1 107.5 108.7 126.4 79.7 190.9 108.8 167.7 247.0 80.6 168.1 109.8 88.3 258.3 163.9 93.8 116.0 263.7 226.1 89.2 152.0 114.1 96.9 247.9 1082.7 298.6 111.7 199.3 1449.6 85.2 100.7 147.1 70.7 174.9 161.2 383.8 133.9 109.4 408.7 155.5 85.7 1254.3 624.2 122.2 1006.3 137.9 118.8 171.5 131.3 1091.1 118.6 227.0 168.3 683.9 100.3 815.7 101.8 204.1 1586.9 92.9 95.6 100.4 135.9 93.6 101.2 97.0 96.7 99.6 101.6 99.1 113.5 45.2 28.9 47.7 19.9 33.3 39.6 77.1 30.8 34.7 46.6 55.3 37.5 15.7 41.5 40.0 38.6 16.7 51.7 28.9 4.7 5.9 59.0 64.8 13.8 46.4 49.6 19.9 40.1 28.4 42.1 66.5 56.6 14.8 18.2 84.9 34.6 47.5 9.3 251.9 25.2 39.2 8.1 20.3 315.8 328.8 87.6 31.4 271.3 67.6 31.9 227.2 120.3 28.8 27.6 22.7 22.2 6.0 39.5 34.2 42.4 3.2 18.5 32.3 37.0 19.7 30.5 49.3 17.5 33.0 19.1 27.3 41.2 43.5 39.4 11.4 35.6 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 30.8" "Cell type enhanced" "Detected in many" "granulocytes: 75.4;Hofbauer cells: 71.7;Kupffer cells: 93.0;Langerhans cells: 67.8;Macrophages: 64.5;monocytes: 52.8;Pancreatic endocrine cells: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.7;eosinophil: 906.5;neutrophil: 747.1" "Group enriched" "Detected in many" 5 "granulocytes: 906.5;monocytes: 256.7" "Group enriched" "Detected in some" 4 "HBEC3-KT: 36.6;HMC-1: 131.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" 10.4 2.4 4.3 30.8 4.7 41.1 3.4 4.7 5.6 3.4 4.1 5.5 4.1 1.7 1.2 7.2 2.6 7.2 2.0 3.8 5.1 2.7 4.1 17.8 13.5 8.9 6.6 1.3 2.0 1.6 0.6 7.3 7.7 1.5 6.7 0.5 2.3 1.5 0.7 5.4 6.3 7.9 8.1 14.4 3.8 1.3 7.2 3.6 1.9 2.6 18.0 14.4 1.9 11.8 20.1 0.2 0.1 0.4 0.2 0.0 0.5 0.0 0.0 0.7 0.2 0.2 5.7 1.3 0.1 0.1 0.3 13.5 0.5 36.6 0.8 0.4 0.6 7.7 0.2 0.9 0.1 1.9 131.3 0.0 6.0 0.4 0.4 0.0 0.2 0.1 0.5 0.4 0.0 1.3 0.2 19.3 0.6 0.5 0.2 0.3 0.1 0.1 8.7 2.1 0.3 0.1 0.1 18.1 0.2 0.4 0.4 5.4 0.1 0.2 0.7 0.0 0.2 1.2 1.1 5.6 0.1 2.4 0.6 61.7 256.7 906.5 0.6 77.9 1.2 12.5 0.4 0.4 116.1 6.7 0.5 0.7 747.1 0.7 34.1 1.3 1.2 112.4 4.3 4.7 4.7 5.6 3.8 5.1 8.9 6.6 7.7 8.1 7.2 11.8 2.1 6.4 6.7 0.0 4.1 6.5 2.0 37.9 5.2 1.5 0.8 0.5 2.2 1.5 20.9 1.8 2.1 0.6 2.9 0.4 0.0 18.1 0.4 0.5 0.2 7.3 0.0 4.0 0.9 5.1 0.5 1.3 1.1 0.5 75.4 2.0 2.9 1.0 71.7 0.0 0.7 0.0 18.3 93.0 67.8 0.2 0.6 64.5 0.0 15.0 52.8 0.2 0.0 1.5 6.6 89.8 0.6 0.0 0.5 0.6 0.3 0.2 20.2 0.9 0.0 0.6 1.0 2.3 0.7 3.2 2.8 1.5 2.0 0.0 0.4 9.4 RAB20 FLJ20429 ENSG00000139832 "RAB20, member RAS oncogene family" Q9NX57 13 110523066-110561722 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 91.3;Hofbauer cells: 105.0;Kupffer cells: 92.1;Macrophages: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 60.9;SK-BR-3: 85.7;T-47d: 54.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002882, HPA052111, HPA068647" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA002882: , HPA052111: AB_2681732, HPA068647: AB_2686013" "unprognostic (5.59e-3)" "unprognostic (1.30e-1)" "unprognostic (3.48e-1)" "unprognostic (1.42e-3)" "unprognostic (1.30e-1)" "unprognostic (3.82e-2)" "unprognostic (1.14e-2)" "unprognostic (5.99e-2)" "unprognostic (9.43e-2)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (2.65e-1)" "prognostic favorable (8.57e-4)" "unprognostic (6.96e-2)" "unprognostic (4.32e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.48e-4)" 31.1 55.4 5.7 21.7 5.5 25.3 23.4 5.6 7.9 11.7 9.6 20.7 27.6 6.9 4.8 4.6 11.5 18.0 21.4 5.2 7.0 26.1 51.4 30.7 16.4 7.0 6.0 20.5 24.2 6.2 9.7 22.8 6.8 12.1 14.3 2.6 10.7 5.0 5.8 4.6 25.3 7.6 6.6 44.5 28.6 10.6 7.4 3.9 22.0 2.3 5.1 20.6 6.7 8.4 20.1 2.9 1.9 3.8 12.4 3.3 31.3 1.7 6.2 8.1 12.5 47.9 39.9 0.0 13.9 1.7 10.8 7.5 3.8 12.3 4.2 22.5 3.0 19.8 3.6 22.6 7.8 2.8 5.7 6.9 2.0 4.2 1.2 6.3 3.1 3.3 3.8 0.0 1.8 24.0 0.1 29.0 4.0 60.9 8.5 1.9 0.1 9.0 14.2 26.3 0.5 2.1 3.8 85.7 27.4 6.2 54.4 30.5 2.3 2.0 4.2 0.2 2.7 0.1 0.0 0.2 27.7 38.9 4.2 7.8 35.5 7.1 1.0 33.3 1.3 3.5 2.8 0.9 15.8 2.8 6.5 2.3 26.3 0.0 26.6 0.8 0.9 11.2 5.7 5.5 5.6 7.9 5.2 7.0 7.0 6.0 6.8 6.6 7.4 8.4 18.6 19.2 20.4 4.2 10.6 4.5 10.9 14.1 10.8 0.2 12.8 13.0 5.0 48.6 16.2 25.8 0.0 34.6 1.8 31.1 31.3 60.3 1.6 20.7 2.6 10.3 18.0 0.0 0.4 67.9 91.3 11.5 15.3 23.2 21.0 41.1 53.6 34.5 105.0 0.0 0.4 23.9 28.5 92.1 19.9 1.6 3.7 100.5 7.2 8.4 16.2 7.4 0.0 4.5 0.1 36.4 17.2 6.4 0.4 8.0 48.1 68.9 20.4 2.0 13.1 6.2 26.2 1.0 13.2 1.9 3.0 20.0 3.6 7.2 24.0 11.1 RAB42 MGC45806 ENSG00000188060 "RAB42, member RAS oncogene family" Q8N4Z0 1 28592200-28595449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 24.5" "Cell type enriched" "Detected in many" 7 "Hofbauer cells: 91.3" "Cancer enhanced" "Detected in many" "renal cancer: 10.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 10.0;Hep G2: 14.3;HSkMC: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050290 Approved "Endoplasmic reticulum" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum" "HPA050290: AB_2681075" "unprognostic (1.10e-1)" "unprognostic (2.56e-1)" "unprognostic (1.72e-1)" "unprognostic (1.00e-1)" "unprognostic (8.25e-2)" "unprognostic (7.59e-2)" "unprognostic (2.00e-4)" "unprognostic (8.81e-2)" "unprognostic (2.39e-1)" "unprognostic (4.09e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (1.52e-2)" "unprognostic (8.77e-2)" "unprognostic (3.02e-2)" "unprognostic (8.83e-2)" "unprognostic (2.07e-3)" 3.0 0.7 0.9 1.7 1.1 0.8 2.2 1.5 2.9 2.2 1.5 2.1 1.4 1.7 0.6 0.7 1.0 1.7 0.9 0.9 0.8 0.9 1.2 2.8 6.6 1.9 1.3 0.4 0.5 2.7 0.3 4.5 1.6 0.7 2.3 0.9 2.6 0.6 0.3 0.6 1.6 1.5 1.1 3.5 1.3 1.4 2.3 24.5 0.6 0.6 3.6 1.9 1.1 3.9 0.1 0.7 0.9 0.0 4.1 10.0 0.0 0.4 3.8 4.1 5.3 2.0 1.5 0.2 2.0 4.3 0.4 0.2 4.1 0.0 2.7 0.1 0.0 0.3 6.8 14.3 1.7 1.1 0.0 8.8 0.1 2.2 0.0 0.4 1.2 0.1 0.1 0.1 0.9 0.0 0.1 2.2 4.8 0.0 0.0 6.5 0.0 1.7 1.8 0.0 0.3 1.5 3.7 0.1 0.0 0.6 0.2 1.8 0.4 0.0 1.2 3.9 0.0 0.3 2.1 0.2 0.1 3.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.9 1.1 1.5 2.9 0.9 0.8 1.9 1.3 1.6 1.1 2.3 3.9 0.5 0.0 0.0 0.0 0.7 0.1 0.2 0.7 0.0 0.5 1.2 1.0 0.4 1.5 1.0 0.0 0.0 0.6 0.1 0.2 0.0 8.5 5.3 3.4 3.9 0.3 0.0 0.4 0.1 0.0 0.8 3.4 0.0 3.2 0.0 0.5 2.5 0.0 91.3 0.0 0.1 0.1 0.0 3.5 1.7 12.2 1.5 11.7 0.0 1.0 1.1 1.0 0.0 0.0 0.1 2.9 1.2 0.0 1.2 0.2 0.3 0.5 0.4 0.9 0.0 4.5 0.9 2.5 1.8 0.4 0.4 0.4 0.3 0.2 0.1 0.1 RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Excitatory neurons: 176.1;Inhibitory neurons: 141.8;Kupffer cells: 109.1;Oligodendrocytes: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;HSkMC: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" 24.7 16.8 22.7 19.9 25.3 1.6 17.1 17.3 27.0 18.6 21.5 11.3 8.7 18.0 6.3 10.6 15.2 22.5 17.0 27.1 21.7 28.6 16.2 20.9 22.9 23.7 20.7 19.2 6.8 8.9 9.5 16.1 17.4 13.2 12.8 15.7 7.7 11.6 2.7 8.9 10.6 22.2 21.1 45.4 6.9 14.7 23.9 8.7 9.1 7.7 10.1 18.7 8.9 28.5 0.3 1.5 26.3 4.0 35.0 16.1 26.7 12.4 20.6 5.5 6.8 12.2 0.7 0.3 11.3 8.8 4.3 0.6 1.8 3.1 5.4 0.4 1.9 0.2 2.6 12.6 9.3 0.4 1.5 54.9 0.7 14.0 3.3 26.2 20.8 2.7 0.0 19.6 11.8 0.1 2.9 0.2 9.6 0.9 0.7 23.7 1.7 24.3 1.5 7.5 3.3 7.9 3.9 4.2 2.1 8.5 0.2 0.3 15.3 7.9 3.1 24.7 6.8 2.0 0.5 0.1 8.3 0.3 22.2 0.0 0.8 0.0 0.0 2.1 0.1 0.0 0.3 0.0 0.9 0.0 0.4 0.2 0.0 0.0 0.8 0.0 0.2 0.5 22.7 25.3 17.3 27.0 27.1 21.7 23.7 20.7 17.4 21.1 23.9 28.5 9.4 9.6 12.3 133.5 1.6 8.2 2.2 2.5 5.2 5.1 6.7 4.6 8.7 5.7 9.0 5.5 0.0 5.1 0.6 2.6 5.9 4.0 13.8 7.9 23.2 19.7 0.0 0.4 176.1 0.9 2.6 22.0 3.6 24.1 3.8 11.0 41.4 2.6 43.3 8.4 141.8 0.8 4.1 109.1 50.4 17.6 13.1 43.7 5.4 76.8 1.7 23.0 0.0 38.7 184.3 1.0 0.1 20.7 0.1 3.5 2.8 30.1 14.2 2.0 26.3 1.2 9.7 4.0 2.5 5.8 4.7 5.2 2.2 13.1 0.6 2.9 RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 42000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Cytokinetic bridge" "HPA009975: AB_1078811, HPA074840: " "unprognostic (2.54e-2)" "unprognostic (3.53e-1)" "unprognostic (2.35e-2)" "unprognostic (3.97e-3)" "unprognostic (1.50e-1)" "unprognostic (2.50e-3)" "unprognostic (2.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.94e-3)" "prognostic favorable (6.70e-8)" "unprognostic (1.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.79e-3)" "unprognostic (2.04e-3)" 30.1 22.7 37.2 16.2 40.2 24.1 26.7 38.4 48.6 18.0 31.2 18.1 43.8 15.9 5.4 22.6 18.8 16.7 16.4 36.3 36.1 18.4 37.0 36.5 15.6 40.2 38.6 17.2 27.2 36.3 10.9 19.4 36.0 17.2 9.0 6.7 33.3 15.4 20.7 21.1 51.7 11.2 37.7 13.0 21.5 13.8 42.9 15.0 19.9 14.1 8.4 20.3 17.6 41.2 19.7 17.7 21.0 35.9 19.2 17.2 36.3 50.2 19.8 34.9 25.6 63.7 21.7 16.7 65.0 27.0 26.0 66.3 26.9 37.3 3.7 44.2 33.1 53.6 51.4 31.6 62.9 36.4 41.1 30.9 34.0 25.2 23.9 16.3 24.8 32.6 57.4 44.9 15.1 40.0 27.7 23.6 16.7 52.7 34.6 42.6 25.1 38.9 28.8 32.7 49.8 18.1 39.9 53.4 19.5 8.2 41.6 39.1 37.3 37.8 27.0 51.1 42.5 34.0 42.7 26.7 26.8 38.2 42.2 4.0 13.2 5.5 28.2 17.8 25.0 16.0 20.6 26.0 14.4 13.7 15.9 17.3 2.1 65.1 22.3 54.2 20.3 26.6 37.2 40.2 38.4 48.6 36.3 36.1 40.2 38.6 36.0 37.7 42.9 41.2 20.1 32.1 28.1 18.6 11.0 15.7 16.4 26.9 15.9 20.0 21.0 13.6 8.1 15.7 27.8 18.4 4.2 44.4 22.4 17.2 1.9 27.7 2.8 20.7 17.8 18.1 4.9 42.7 23.5 22.0 28.5 17.8 13.7 22.0 19.0 8.6 17.5 36.4 110.7 18.5 18.2 12.3 26.4 14.7 10.4 3.4 16.8 21.0 19.6 8.4 11.7 21.6 43.3 16.1 21.8 21.8 16.7 14.3 18.0 17.3 77.6 14.5 29.3 17.3 6.6 22.2 16.0 40.4 40.4 21.9 11.9 62.8 18.3 16.7 21.4 23.1 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812770-149962139 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 591.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 462.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA064784: AB_2685350" "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favorable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 48.2 41.2 58.1 40.4 95.2 19.9 53.9 88.1 91.5 33.6 63.7 35.0 28.9 33.3 57.2 32.6 30.2 40.6 34.4 55.0 77.3 67.9 73.8 64.1 38.0 101.8 83.9 35.6 36.1 52.3 18.3 64.1 100.8 46.6 37.1 40.4 75.5 39.3 36.5 32.5 30.5 36.9 85.6 53.0 34.3 25.2 75.9 32.0 64.0 42.6 33.2 42.3 28.9 131.0 60.6 39.4 24.4 29.0 92.2 55.2 40.3 32.2 86.2 32.3 47.4 33.4 84.4 26.6 48.7 42.0 58.7 58.0 37.5 41.5 42.9 34.1 24.6 35.8 17.3 31.2 61.5 35.0 41.8 59.9 73.1 26.5 71.8 37.3 37.0 24.9 10.1 49.7 28.0 34.5 26.2 18.8 16.8 58.6 29.1 19.0 26.7 108.5 54.2 29.6 12.6 37.6 28.5 39.9 110.3 19.2 79.2 34.0 37.8 40.8 16.5 45.6 23.4 89.9 61.9 51.5 35.9 30.1 23.6 98.2 130.1 106.5 37.4 153.8 48.8 51.9 41.5 44.8 93.1 48.4 38.0 42.4 462.3 46.3 207.8 68.3 48.7 104.5 58.1 95.2 88.1 91.5 55.0 77.3 101.8 83.9 100.8 85.6 75.9 131.0 100.9 109.0 72.3 78.7 55.3 73.5 68.2 84.3 74.0 44.5 54.5 51.1 27.3 48.6 68.1 47.8 29.2 101.2 61.9 30.2 43.0 63.0 2.5 32.5 34.5 69.4 20.3 32.4 122.1 70.6 83.5 84.8 31.6 39.7 60.8 14.6 80.3 53.7 201.2 21.9 98.8 27.7 67.1 183.9 173.7 6.7 76.1 177.6 103.2 92.8 93.5 98.5 38.1 115.6 591.2 58.7 33.6 88.0 62.4 71.9 38.5 71.5 40.4 37.2 92.1 76.3 55.5 23.6 32.5 52.3 72.5 52.5 49.8 38.2 27.7 55.8 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 63.3" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA021576: AB_1856331, HPA052404: AB_2681817" "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 20.9 12.9 11.1 13.5 12.5 11.6 18.6 11.2 14.2 16.0 15.1 17.5 13.6 13.3 16.5 22.4 15.7 9.6 8.5 10.4 11.3 21.6 8.6 15.5 13.9 13.9 13.2 12.6 13.5 16.8 5.6 18.1 12.4 14.0 18.0 2.3 15.2 15.2 7.4 26.2 13.9 13.7 12.8 25.8 11.9 5.1 16.4 7.9 15.8 10.1 12.6 14.8 17.3 13.8 12.7 25.6 1.5 25.4 34.0 28.5 22.7 9.7 14.9 9.4 8.4 0.0 9.4 11.5 14.8 19.0 17.0 17.0 13.2 12.1 7.8 10.0 5.6 4.8 8.1 0.0 24.3 12.8 10.7 27.7 63.3 10.1 33.5 16.1 15.8 0.0 0.0 34.9 15.6 17.0 0.1 13.5 10.5 25.7 14.4 27.9 0.0 39.2 13.6 18.2 9.8 0.5 14.9 5.9 14.9 16.6 39.4 20.2 13.3 0.0 3.5 15.6 11.5 0.4 1.3 7.3 16.5 22.1 13.3 25.3 61.6 31.3 12.8 57.3 7.2 28.4 6.8 6.8 46.4 28.4 3.7 6.2 54.0 13.9 70.2 17.1 10.1 29.2 11.1 12.5 11.2 14.2 10.4 11.3 13.9 13.2 12.4 12.8 16.4 13.8 14.1 3.2 5.9 7.8 14.1 9.3 13.4 16.8 22.2 0.1 13.1 15.0 4.0 7.2 7.8 11.0 0.0 47.5 10.5 23.4 29.4 9.9 0.4 14.5 12.8 13.2 4.9 11.2 0.8 18.6 37.1 13.2 5.6 12.4 1.3 14.1 25.4 2.7 51.1 0.0 1.0 12.0 8.2 73.9 8.4 1.6 16.8 35.5 16.0 26.2 45.3 3.9 19.6 9.0 0.7 11.9 13.1 15.4 9.0 22.2 27.5 49.3 10.4 0.6 26.3 8.2 14.2 0.7 4.0 24.1 14.6 43.6 7.5 10.6 14.6 11.2 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160182-31207019 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favorable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 19.8 18.7 21.5 14.4 22.5 10.1 22.8 21.7 25.1 22.3 22.5 23.4 20.5 22.5 25.1 25.9 23.0 16.4 21.1 22.5 22.1 36.2 48.4 19.0 16.2 21.7 22.0 26.1 19.2 48.8 15.8 21.0 22.0 38.2 22.2 16.5 30.2 28.7 23.4 29.9 21.9 25.6 21.9 16.6 21.7 10.8 23.2 21.0 52.0 25.5 21.3 24.2 23.0 23.6 23.7 13.8 26.1 29.9 51.8 34.5 24.9 27.7 53.3 37.2 50.2 15.6 11.1 22.5 15.2 49.3 32.8 14.6 25.3 28.6 38.1 22.6 27.5 9.8 13.2 19.1 72.5 24.1 14.6 37.1 100.8 26.2 60.2 34.0 31.7 23.5 11.7 26.2 45.2 16.8 20.8 13.5 11.7 48.8 15.2 21.1 26.1 26.5 27.0 20.4 11.6 23.4 20.2 26.5 41.0 26.7 18.4 15.8 22.2 26.1 18.7 30.9 13.6 36.2 31.6 28.4 34.5 15.1 21.4 16.9 15.7 9.0 12.2 15.8 13.6 10.0 12.4 13.8 13.3 8.2 12.5 11.5 22.3 16.9 13.7 4.9 14.6 14.8 21.5 22.5 21.7 25.1 22.5 22.1 21.7 22.0 22.0 21.9 23.2 23.6 9.3 22.4 12.6 10.7 8.8 9.1 10.3 10.0 9.6 11.0 14.2 10.8 5.5 20.0 11.5 18.4 8.4 13.0 11.3 16.4 21.5 15.1 19.0 8.9 8.2 8.5 16.8 5.0 14.0 14.9 23.2 10.9 8.2 10.3 5.7 8.4 23.2 28.9 14.2 8.4 17.3 15.8 14.2 8.8 7.5 18.3 7.5 10.5 8.8 10.3 10.7 11.9 7.2 13.6 22.5 15.5 12.7 15.8 6.8 14.5 17.7 22.9 12.4 7.8 6.6 9.5 9.3 7.4 9.8 10.6 10.7 37.2 7.2 6.0 7.8 9.8 RNH1 "RAI, RNH" ENSG00000023191 "Ribonuclease/angiogenin inhibitor 1" P13489 11 494512-507300 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 262.3;monocytes: 299.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039223, HPA040781" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 22000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA039223: AB_10795581, HPA040781: AB_10796227" "unprognostic (1.87e-1)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.48e-3)" "unprognostic (6.09e-2)" "unprognostic (4.82e-3)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.44e-1)" "prognostic favorable (2.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.66e-1)" "unprognostic (4.78e-2)" "unprognostic (4.35e-2)" 163.5 137.2 27.3 29.0 41.8 46.3 133.7 42.4 33.9 156.4 28.9 123.0 27.1 140.8 10.0 215.0 119.5 29.7 198.0 26.3 32.5 118.6 111.9 146.7 30.8 48.6 39.7 119.1 89.5 25.6 80.6 27.3 38.2 100.9 8.8 5.6 112.5 31.0 145.9 257.4 91.1 25.3 35.3 113.3 101.1 90.1 38.3 15.6 106.6 21.8 13.9 144.5 160.3 49.4 86.5 123.9 13.2 39.8 66.3 93.8 43.9 70.6 51.3 68.9 58.3 61.9 92.9 41.8 54.3 175.1 41.9 72.7 20.6 76.5 10.4 51.3 104.9 28.2 28.5 65.7 243.3 39.8 90.0 77.1 108.2 40.2 46.7 29.2 47.9 27.7 36.2 71.3 37.7 86.6 30.5 78.4 19.8 45.3 112.6 37.7 22.3 55.8 40.7 34.6 35.7 23.2 41.8 59.1 73.7 7.4 44.6 122.2 77.3 109.3 32.8 39.8 49.5 44.9 53.0 32.2 117.5 81.9 74.3 37.6 246.2 57.3 51.1 298.9 59.9 63.0 55.3 51.1 262.3 48.4 49.8 45.1 17.1 54.2 299.1 71.7 58.4 236.5 27.3 41.8 42.4 33.9 26.3 32.5 48.6 39.7 38.2 35.3 38.3 49.4 156.0 112.2 83.5 18.9 92.3 202.1 239.0 265.0 89.4 102.4 82.0 105.5 83.3 88.6 138.6 79.1 110.5 222.2 85.3 126.6 225.0 188.8 105.1 72.8 132.4 136.1 57.4 59.7 10.9 164.4 217.4 194.9 64.2 82.8 140.2 93.8 101.7 68.6 374.0 168.2 14.5 115.6 148.5 191.8 323.0 42.7 211.6 230.3 193.9 12.2 334.2 144.6 79.3 10.1 70.8 171.6 120.5 179.8 101.7 161.0 139.4 242.3 97.9 146.4 177.5 99.1 178.0 153.4 157.8 140.0 260.0 305.5 96.5 199.7 114.4 217.4 SDCCAG8 "BBS16, CCCAP, NPHP10, NY-CO-8, SLSN7" ENSG00000054282 "SHH signaling and ciliogenesis regulator SDCCAG8" Q86SQ7 1 243256034-243500091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 284.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "WM-115: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025737, HPA044477, HPA072495" Approved Enhanced Centrosome NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Centrosome "HPA025737: AB_2671761, HPA044477: AB_2678955, HPA072495: AB_2686527" "unprognostic (4.12e-1)" "unprognostic (3.94e-2)" "unprognostic (7.58e-2)" "unprognostic (2.86e-2)" "unprognostic (2.61e-1)" "unprognostic (3.78e-2)" "unprognostic (9.34e-2)" "unprognostic (3.95e-2)" "unprognostic (4.37e-2)" "unprognostic (5.97e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-2)" "unprognostic (1.38e-3)" "unprognostic (1.13e-1)" "unprognostic (1.89e-1)" "unprognostic (3.68e-3)" "unprognostic (4.69e-2)" 11.6 9.8 7.1 3.8 7.6 3.5 11.3 7.1 7.4 9.6 6.8 8.4 2.9 7.9 7.3 8.0 9.4 7.5 8.8 7.6 7.1 9.3 7.4 11.8 5.2 8.6 7.9 11.0 14.3 7.0 11.6 4.5 7.7 8.9 3.1 3.7 8.4 3.8 12.1 8.1 7.6 3.0 8.3 8.3 8.4 5.3 7.7 3.3 17.1 2.3 2.7 8.9 8.9 8.9 6.2 5.4 2.0 3.8 7.3 3.4 6.3 4.4 3.4 2.1 1.7 4.9 10.9 2.4 6.5 3.7 0.7 2.2 0.6 4.9 2.0 3.7 6.9 2.3 3.7 2.0 3.7 2.2 5.1 7.0 6.2 4.8 7.7 7.9 5.5 5.2 3.2 3.3 3.9 1.9 0.9 4.9 1.2 9.4 9.5 3.1 1.1 2.1 7.5 4.1 5.6 5.7 4.3 2.6 10.6 0.9 4.3 2.8 5.2 6.8 1.5 2.4 2.5 5.1 2.7 1.2 3.0 4.1 29.9 7.6 7.8 6.6 3.8 8.0 2.8 5.2 4.3 5.3 7.1 6.9 6.1 4.2 4.7 9.0 4.5 5.6 3.8 3.8 7.1 7.6 7.1 7.4 7.6 7.1 8.6 7.9 7.7 8.3 7.7 8.9 30.6 41.7 103.6 139.7 39.0 37.2 39.6 59.1 56.9 69.8 34.9 37.1 28.5 50.1 52.0 40.5 87.6 48.1 16.1 16.5 76.3 63.1 17.8 60.9 31.6 36.2 31.9 23.3 170.5 30.0 86.3 38.5 24.5 31.4 49.9 29.8 45.7 27.8 130.1 65.6 153.2 18.1 63.1 51.0 32.5 33.8 52.8 51.7 35.6 188.3 45.9 67.1 22.6 165.4 284.0 50.1 26.4 44.4 30.8 33.6 31.5 39.0 73.5 80.3 39.5 34.8 32.0 51.4 20.7 38.8 49.2 26.3 23.1 50.0 25.2 29.9 SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2087.6;liver: 6268.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 448.7;Alveolar cells type 2: 529.3;Granulosa cells: 458.1;Hofbauer cells: 858.5;Macrophages: 373.3;Proximal tubular cells: 1044.7" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Hep G2: 567.4;HSkMC: 451.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 2220000000 1800000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" 719.1 424.3 164.8 179.9 345.6 40.1 617.5 386.0 290.0 460.0 145.5 644.0 620.0 335.8 459.7 240.7 376.5 670.5 237.2 156.3 231.3 853.7 6268.1 512.0 552.4 519.4 316.4 701.2 229.0 246.0 108.3 973.0 490.3 214.2 714.2 59.2 170.8 374.1 156.4 171.8 2087.6 233.2 310.3 948.8 257.0 87.8 284.7 170.4 147.0 265.6 177.4 414.3 213.1 524.3 0.7 1.7 7.7 1.0 43.6 12.2 7.3 4.1 10.9 0.0 0.0 12.5 65.3 2.0 36.3 1.5 1.4 1.7 0.2 0.1 0.0 2.4 52.7 3.1 0.2 567.4 25.9 3.2 0.4 451.1 0.7 0.0 0.1 1.9 0.1 1.5 6.4 12.9 23.5 1.3 1.1 6.4 30.6 17.0 0.9 1.3 2.0 100.8 12.5 8.0 2.2 2.7 2.7 16.7 1.6 54.6 125.4 0.7 0.7 3.2 1.7 5.2 1.0 8.4 1.5 2.0 1.7 5.9 1.5 0.1 0.1 0.5 0.5 0.1 0.6 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.5 0.6 0.2 0.9 0.3 0.3 164.8 345.6 386.0 290.0 156.3 231.3 519.4 316.4 490.3 310.3 284.7 524.3 312.7 448.7 529.3 0.0 15.2 0.0 0.0 0.0 0.0 0.0 312.0 271.1 0.0 0.0 102.1 125.0 0.0 223.4 9.4 0.0 197.6 73.4 0.0 83.8 231.0 75.8 0.0 0.0 0.0 52.8 17.5 358.7 0.0 116.1 26.5 458.1 0.0 0.0 858.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 373.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 4.9 0.0 0.0 1044.7 52.5 0.0 0.0 0.0 133.1 0.0 0.0 0.0 0.0 112.9 10.0 361.8 0.0 0.0 SESN1 "PA26, SEST1" ENSG00000080546 "Sestrin 1" Q9Y6P5 6 108986437-109094819 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 137.2;Excitatory neurons: 134.9;Inhibitory neurons: 127.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 48.0;NK-cells: 58.9;T-cells: 74.6" "Cell line enhanced" "Detected in all" "BEWO: 80.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073659 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Nucleoli fibrillar center" Nucleoplasm "HPA073659: AB_2686622" "unprognostic (2.22e-1)" "unprognostic (5.97e-2)" "unprognostic (1.02e-1)" "unprognostic (3.52e-2)" "unprognostic (1.17e-1)" "prognostic favorable (6.47e-5)" "unprognostic (2.68e-1)" "unprognostic (6.91e-2)" "unprognostic (1.01e-1)" "unprognostic (8.33e-2)" "unprognostic (1.83e-3)" "prognostic favorable (2.07e-4)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (7.95e-2)" 30.7 26.6 29.1 23.2 30.7 50.2 42.3 29.8 35.9 29.9 29.8 31.6 20.2 31.7 26.6 22.7 32.5 18.5 36.2 31.1 29.4 16.7 29.2 25.6 33.8 27.9 27.9 62.6 31.6 50.3 25.8 53.4 28.7 25.1 23.9 25.0 18.3 23.6 151.2 43.1 38.1 32.9 28.7 37.0 31.0 42.0 29.9 21.9 32.1 140.0 33.8 28.3 28.2 30.8 3.5 5.7 25.7 12.2 32.1 40.6 80.5 13.8 15.7 4.7 9.0 10.9 3.6 29.3 11.4 10.2 3.7 4.1 7.0 27.6 5.8 2.6 34.7 13.0 6.9 40.9 19.7 5.1 12.7 44.2 43.0 8.5 13.7 20.5 24.7 8.3 9.7 20.5 23.3 6.9 11.3 16.4 10.6 5.7 3.6 9.0 7.3 13.7 10.1 17.4 6.3 12.7 7.5 4.7 5.7 41.3 4.5 33.5 15.3 3.6 7.1 3.3 4.5 20.5 12.5 12.0 7.9 12.8 7.9 11.9 2.7 3.4 34.4 6.3 74.6 13.3 32.4 27.3 2.7 48.0 39.6 20.8 10.0 58.9 8.7 5.4 15.1 20.3 29.1 30.7 29.8 35.9 31.1 29.4 27.9 27.9 28.7 28.7 29.9 30.8 13.9 64.1 22.4 79.0 37.3 6.5 4.9 7.4 25.0 23.8 14.2 14.5 30.0 17.2 15.2 14.7 45.9 57.8 22.9 12.7 9.8 4.3 137.2 10.3 15.2 9.8 15.5 24.2 134.9 5.3 13.7 21.9 28.5 8.2 3.8 17.4 10.8 14.7 44.9 26.9 127.7 10.0 2.0 43.1 11.3 104.8 34.5 56.5 16.0 71.2 9.4 39.1 25.7 64.3 119.1 3.1 11.9 35.3 26.2 9.4 7.8 9.3 26.4 44.3 26.3 43.9 15.9 18.4 16.2 25.4 8.4 44.6 41.8 102.9 13.6 4.3 SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Hofbauer cells: 78.6;Kupffer cells: 93.4;Macrophages: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enriched" "Detected in single" 19 "THP-1: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" 23.0 13.7 2.0 7.7 2.9 12.3 8.6 1.9 6.5 1.8 7.5 10.2 5.1 2.0 1.8 2.2 7.0 8.5 6.4 1.8 2.2 3.9 8.4 16.7 12.7 10.2 3.3 2.7 1.6 0.5 2.3 18.8 10.9 1.9 6.6 0.3 5.4 1.2 3.7 3.0 11.2 7.7 5.0 18.9 5.1 2.5 10.9 3.6 3.7 2.6 1.9 7.6 3.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.0 2.9 1.9 6.5 1.8 2.2 10.2 3.3 10.9 5.0 10.9 3.9 0.5 3.2 4.4 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.3 2.4 0.0 0.6 0.0 2.1 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.3 0.0 0.0 93.4 6.3 0.1 0.0 42.6 0.0 3.7 2.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 1.4 1.0 0.0 0.1 0.6 0.6 1.9 0.4 0.0 0.0 0.0 SIGLEC15 "CD33L3, HsT1361" ENSG00000197046 "Sialic acid binding Ig like lectin 15" Q6ZMC9 18 45825675-45844094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.7;intestine: 3.0;urinary bladder: 1.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.6;Hofbauer cells: 10.1;Macrophages: 3.7;Pancreatic endocrine cells: 3.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "classical monocyte: 3.0;myeloid DC: 1.0" "Group enriched" "Detected in many" 21 "dendritic cells: 1.0;monocytes: 3.0" "Cell line enriched" "Detected in some" 5 "U-87 MG: 124.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053509 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA053509: " "unprognostic (3.89e-3)" "unprognostic (1.87e-2)" "unprognostic (1.77e-1)" "unprognostic (7.18e-3)" "unprognostic (2.27e-1)" "unprognostic (8.07e-2)" "unprognostic (5.91e-2)" "unprognostic (2.71e-1)" "unprognostic (9.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-2)" "unprognostic (7.65e-2)" "unprognostic (6.55e-2)" "unprognostic (1.42e-1)" "unprognostic (6.06e-2)" "unprognostic (4.40e-2)" "prognostic favorable (9.14e-5)" 0.0 0.4 0.1 0.3 0.4 0.0 1.7 0.6 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 3.0 0.0 0.0 1.0 1.3 0.0 0.0 0.2 0.0 0.0 0.6 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.3 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.4 10.9 2.1 0.3 0.0 22.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 5.5 0.0 0.1 1.3 0.0 0.0 0.0 124.2 2.9 0.2 0.0 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 0.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.9 1.3 0.0 0.0 1.0 3.6 0.9 0.8 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.5 0.4 0.2 1.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.7 0.0 0.0 2.2 0.4 10.1 1.7 0.1 0.2 0.0 1.6 2.5 0.0 0.0 3.7 0.0 0.0 1.6 0.0 1.0 0.0 0.0 3.5 0.1 0.0 0.0 1.1 1.2 0.1 0.0 1.0 0.0 1.5 0.4 1.2 0.1 0.0 0.3 0.0 0.3 0.0 0.1 2.8 SIGLEC5 "CD170, CD33L2, OB-BP2, SIGLEC-5" ENSG00000105501 "Sialic acid binding Ig like lectin 5" O15389 19 51611927-51645545 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 14.7;lymphoid tissue: 12.4" "Cell type enhanced" "Detected in some" "granulocytes: 8.2;Hofbauer cells: 5.6;Kupffer cells: 10.4;Macrophages: 4.4;monocytes: 3.0" "Cancer enriched" "Detected in single" 5 "urothelial cancer: 1.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "neutrophil: 152.5;non-classical monocyte: 49.3" "Group enriched" "Detected in many" 6 "granulocytes: 152.5;monocytes: 49.3" "Group enriched" "Detected in some" 5 "HMC-1: 59.2;U-937: 25.6" "HPA009085, CAB024900" Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB024900: , HPA009085: AB_1079965" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (2.02e-2)" "unprognostic (1.03e-2)" "unprognostic (4.39e-2)" "unprognostic (1.62e-2)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (3.28e-1)" "unprognostic (7.44e-2)" "unprognostic (1.01e-1)" "unprognostic (4.05e-1)" "unprognostic (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (3.55e-3)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" 1.4 0.4 0.3 6.6 0.6 14.7 0.2 0.3 1.2 0.2 0.0 0.7 0.1 0.3 0.0 0.3 0.7 0.7 0.4 0.3 0.3 0.3 1.5 3.4 3.1 0.4 0.3 0.1 0.2 0.3 0.1 0.8 0.5 0.3 0.7 0.2 0.3 0.1 0.0 0.0 2.0 0.9 0.4 12.4 0.6 0.8 0.4 0.7 0.2 0.4 2.2 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 15.5 22.2 0.5 0.0 24.2 0.0 2.5 0.0 0.0 15.6 2.0 0.0 0.0 152.5 0.7 49.3 5.0 0.0 8.4 0.3 0.6 0.3 1.2 0.3 0.3 0.4 0.3 0.5 0.4 0.4 0.6 0.0 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 8.2 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 10.4 1.2 0.5 0.3 4.4 0.0 1.0 3.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIRPA "BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2" ENSG00000198053 "Signal regulatory protein alpha" P78324 20 1894167-1940592 "CD markers, Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 157.3" "Cell type enhanced" "Detected in many" "Astrocytes: 138.1;Excitatory neurons: 87.4;Hofbauer cells: 100.8;Macrophages: 82.5;monocytes: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 24.1;eosinophil: 48.7;myeloid DC: 13.9;neutrophil: 50.8" "Group enriched" "Detected in many" 150 "dendritic cells: 13.9;granulocytes: 50.8;monocytes: 24.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 142.7;RPTEC TERT1: 100.3;SK-MEL-30: 120.2" "CAB002776, CAB015122, HPA054437, HPA058511" Enhanced NA NA 130000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "CAB002776: , CAB015122: AB_677430, HPA054437: AB_2682488, HPA058511: AB_2683738" "unprognostic (9.78e-2)" "unprognostic (2.67e-1)" "unprognostic (3.07e-1)" "unprognostic (1.23e-1)" "unprognostic (5.56e-2)" "unprognostic (1.58e-1)" "unprognostic (1.15e-3)" "unprognostic (4.19e-3)" "unprognostic (3.48e-2)" "unprognostic (2.84e-3)" "unprognostic (3.69e-1)" "unprognostic (3.33e-2)" "unprognostic (2.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.55e-2)" "unprognostic (3.55e-2)" "unprognostic (2.24e-2)" 49.7 40.4 145.5 49.2 146.6 44.1 41.2 98.9 157.3 27.2 56.0 16.6 27.0 15.0 19.9 13.1 23.3 27.3 30.3 155.1 105.0 27.3 53.4 42.3 22.5 101.0 123.4 19.5 12.6 4.8 15.9 26.3 94.9 15.6 14.8 39.8 29.9 15.3 17.4 29.8 22.3 21.6 99.9 28.1 11.8 6.9 135.2 7.1 12.2 9.0 16.9 35.4 21.9 126.6 11.8 25.2 12.5 23.2 29.4 27.5 1.8 60.5 51.1 16.2 4.9 16.2 0.3 0.0 14.3 142.7 43.6 11.6 10.0 70.6 6.7 0.1 7.1 0.0 2.8 9.0 35.4 24.4 28.5 24.9 32.5 13.8 16.6 46.1 50.8 0.2 1.4 15.4 22.0 0.7 0.0 33.9 13.9 0.0 11.2 0.1 22.2 16.1 100.3 0.0 1.7 3.7 8.2 0.0 120.2 4.5 4.0 76.9 76.6 71.1 36.7 46.4 30.5 0.1 0.1 0.2 22.2 77.3 8.2 0.3 24.1 48.7 0.0 6.0 0.0 0.1 0.0 0.0 13.9 0.0 0.0 0.0 50.8 0.0 2.2 0.9 0.1 10.0 145.5 146.6 98.9 157.3 155.1 105.0 101.0 123.4 94.9 99.9 135.2 126.6 60.6 3.2 6.5 138.1 4.3 14.3 12.8 28.3 6.2 13.2 18.8 27.7 12.7 34.3 10.1 9.2 14.6 20.2 0.6 2.8 1.9 26.8 0.5 1.5 2.2 13.7 9.6 4.4 87.4 2.1 2.1 23.7 1.1 4.8 17.7 1.6 20.3 29.3 100.8 15.2 44.2 3.5 2.0 57.2 54.3 1.2 5.0 82.5 23.2 33.7 85.0 23.7 0.0 40.7 51.1 25.1 9.9 1.9 1.6 9.7 17.7 16.1 5.1 26.8 6.6 3.4 7.8 0.2 8.3 2.8 6.7 36.5 2.1 0.0 2.6 7.7 SLAMF8 "BLAME, CD353, SBBI42" ENSG00000158714 "SLAM family member 8" Q9P0V8 1 159826811-159837492 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 9 "Hofbauer cells: 36.9;Kupffer cells: 19.8;Langerhans cells: 61.8;Macrophages: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 14.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.7;HL-60: 1.4;U-138 MG: 1.9;U-87 MG: 1.0;U-937: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067601 Enhanced NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA067601: AB_2685870" "unprognostic (1.04e-1)" "unprognostic (8.80e-3)" "unprognostic (5.12e-2)" "unprognostic (2.14e-3)" "unprognostic (3.07e-2)" "unprognostic (3.22e-2)" "unprognostic (7.87e-2)" "unprognostic (4.29e-1)" "unprognostic (2.20e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.50e-1)" "unprognostic (4.42e-2)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" 6.9 3.7 1.7 29.8 1.8 0.9 3.0 1.8 3.6 3.8 2.9 7.6 6.6 1.5 0.7 4.2 2.8 8.0 2.6 1.4 2.3 3.9 3.3 16.1 32.9 4.9 3.9 2.8 2.1 0.6 3.5 5.5 5.3 2.5 9.5 0.3 3.4 1.4 0.9 2.8 9.3 7.6 2.5 11.7 4.9 0.8 9.2 10.5 3.0 0.6 17.7 10.3 2.1 4.9 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.9 0.0 0.0 0.3 0.0 0.0 0.0 1.0 1.2 0.0 0.0 5.8 0.0 3.5 8.0 0.2 0.0 1.2 4.6 14.3 0.0 0.2 2.7 0.5 8.8 0.5 0.1 0.0 3.1 1.7 1.8 1.8 3.6 1.4 2.3 4.9 3.9 5.3 2.5 9.2 4.9 0.3 0.0 2.3 0.0 1.0 1.8 0.0 0.0 0.0 0.4 0.1 0.4 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.1 0.8 0.0 0.4 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.2 36.9 0.0 0.1 0.0 0.0 19.8 61.8 0.0 0.3 41.1 0.0 1.0 1.3 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 2.9 0.1 0.0 0.0 1.0 0.5 1.3 0.0 0.0 0.0 SLC18B1 "C6orf192, dJ55C23.6" ENSG00000146409 "Solute carrier family 18 member B1" Q6NT16 6 132769370-132813339 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 93.4;Hofbauer cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "K-562: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029747 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Cytosol "HPA029747: AB_10600797" "unprognostic (1.84e-2)" "unprognostic (3.94e-1)" "unprognostic (4.22e-2)" "unprognostic (2.85e-1)" "unprognostic (2.41e-2)" "prognostic favorable (3.55e-4)" "prognostic unfavorable (7.90e-4)" "unprognostic (1.53e-1)" "unprognostic (2.39e-1)" "unprognostic (4.09e-1)" "unprognostic (6.97e-3)" "unprognostic (1.13e-1)" "prognostic favorable (9.24e-4)" "unprognostic (7.20e-3)" "unprognostic (1.08e-1)" "unprognostic (2.08e-2)" "unprognostic (7.88e-2)" 9.9 8.9 21.0 6.3 21.6 4.6 9.7 22.5 28.0 9.4 23.1 9.7 14.5 6.4 5.8 13.6 9.8 11.9 3.9 21.2 22.2 12.7 7.6 5.7 7.7 21.6 22.3 6.9 9.9 12.9 8.3 15.7 21.0 5.4 10.1 2.6 13.1 4.5 3.2 9.5 10.5 5.9 22.8 8.3 16.1 2.0 25.1 7.9 10.2 3.5 8.1 11.1 7.2 22.8 6.8 6.5 10.0 0.0 1.5 3.2 5.7 2.5 7.2 4.4 13.4 14.9 13.8 0.2 9.2 1.5 7.9 17.3 13.4 15.4 3.3 10.3 27.6 3.6 11.3 16.8 7.5 3.0 0.3 9.3 13.7 7.2 14.5 7.3 13.6 20.7 40.4 2.5 3.8 9.4 10.5 0.3 14.1 15.8 8.7 15.7 11.7 11.8 36.6 11.4 21.2 0.0 12.9 25.2 20.1 6.0 8.9 0.1 6.0 1.9 5.3 2.1 5.7 8.5 0.5 0.4 11.5 0.1 1.7 0.0 14.4 0.8 4.3 3.2 8.1 6.6 6.5 6.0 19.9 9.7 9.5 6.6 0.8 3.4 0.3 15.5 11.9 8.1 21.0 21.6 22.5 28.0 21.2 22.2 21.6 22.3 21.0 22.8 25.1 22.8 10.4 0.0 6.5 93.4 15.2 10.1 10.3 30.4 22.8 5.5 13.0 7.4 3.1 40.0 20.6 27.6 2.1 53.1 8.2 5.4 9.8 32.0 0.2 12.6 4.8 7.8 16.3 49.1 32.2 15.1 19.3 7.8 20.4 5.8 0.0 5.8 18.2 15.6 65.6 0.0 25.3 11.9 32.6 21.5 9.0 0.5 6.8 26.7 14.2 27.2 11.4 9.3 5.2 51.3 4.4 14.6 6.0 4.5 6.6 8.8 7.2 6.4 27.9 3.5 0.0 8.6 4.8 0.3 0.5 25.5 10.9 28.5 7.3 21.7 15.3 13.2 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocytes: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 27.7;SK-MEL-30: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 18.5 24.2 32.9 4.5 41.5 1.5 19.3 37.3 39.0 22.0 45.9 15.2 3.6 13.1 2.9 8.5 17.0 8.2 29.0 32.0 32.8 10.9 7.9 10.4 4.7 41.1 40.3 33.0 14.4 17.7 19.3 6.2 38.6 23.2 1.8 4.0 24.1 10.3 24.9 14.4 7.6 3.9 34.4 10.5 13.7 17.5 35.9 2.2 16.8 12.4 1.6 13.9 14.0 46.7 6.2 3.0 4.1 9.8 27.7 15.2 3.5 4.4 11.2 4.8 7.2 0.5 18.2 2.1 8.1 7.2 4.3 7.3 0.4 6.8 1.3 2.4 1.4 1.2 0.5 2.3 5.4 0.5 6.4 14.1 4.6 4.8 1.9 19.7 3.3 3.9 0.8 1.3 3.2 2.5 3.3 4.9 1.2 6.0 5.2 4.7 3.2 1.4 3.2 1.8 1.4 2.9 3.0 1.5 47.8 2.5 5.2 1.6 2.1 9.4 6.1 7.5 3.0 4.0 3.1 0.7 9.6 5.3 6.7 0.0 9.2 0.2 1.4 4.0 2.6 0.4 1.0 1.7 6.3 0.3 1.3 1.7 0.0 1.6 1.8 6.5 0.7 4.6 32.9 41.5 37.3 39.0 32.0 32.8 41.1 40.3 38.6 34.4 35.9 46.7 19.7 3.2 11.9 84.5 1.8 6.6 14.1 12.7 10.2 8.4 15.5 26.9 19.5 11.5 11.1 9.2 27.1 4.3 8.3 1.2 1.9 11.1 1.1 8.4 6.9 7.8 5.4 0.8 16.1 4.8 15.6 10.4 9.2 4.9 2.5 8.4 10.4 8.1 26.1 6.7 23.9 3.0 6.1 22.4 4.0 2.5 21.5 13.4 8.8 15.0 14.7 11.6 4.1 37.2 67.5 5.2 0.6 11.7 1.7 12.0 0.1 3.6 16.1 17.7 6.6 10.9 7.3 9.1 5.8 5.0 4.5 2.3 4.9 13.8 2.2 8.7 SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 129.9;Karpas-707: 117.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" 18.6 20.7 9.6 7.3 10.5 4.6 16.2 10.1 9.2 14.5 8.4 10.1 7.9 11.9 7.3 22.0 10.7 7.3 13.8 9.6 11.8 19.5 17.7 11.9 6.5 13.9 12.9 8.5 10.3 21.3 10.8 9.4 12.3 11.4 5.7 5.8 14.5 8.1 12.8 21.2 10.0 10.1 10.4 10.8 11.3 5.1 13.0 5.7 16.0 9.9 7.6 12.1 13.0 11.6 24.6 43.6 12.3 32.6 41.7 19.4 20.4 14.9 20.3 16.8 15.2 27.9 44.5 6.6 23.4 18.7 42.0 29.4 18.1 26.9 11.8 11.5 10.1 7.6 16.4 23.3 129.9 7.8 36.4 29.8 26.9 18.9 62.7 7.6 19.9 9.6 14.2 117.3 16.9 40.5 10.0 7.0 7.6 17.2 10.9 8.9 35.9 10.9 44.1 20.3 9.6 12.7 22.8 37.4 25.4 10.1 14.1 8.2 19.2 21.8 24.0 30.7 15.2 23.9 32.6 12.9 23.6 13.4 21.0 12.1 18.1 8.0 11.9 25.6 7.0 4.8 8.2 10.8 11.4 3.6 5.3 7.9 11.7 13.6 30.9 7.8 5.9 9.5 9.6 10.5 10.1 9.2 9.6 11.8 13.9 12.9 12.3 10.4 13.0 11.6 39.0 12.8 10.5 11.8 5.9 17.0 13.2 10.2 7.4 17.2 17.5 10.2 13.5 28.6 11.1 33.1 6.2 24.1 12.0 21.5 7.9 34.2 1.7 13.4 29.7 20.8 9.1 0.8 6.9 38.7 22.3 25.2 12.2 22.8 1.3 11.9 31.8 25.4 51.2 15.2 7.9 11.2 8.2 61.0 16.8 1.5 18.3 28.8 28.4 4.7 19.8 19.2 11.3 9.0 10.8 48.2 14.3 12.0 5.5 18.3 21.5 57.2 9.0 11.1 26.3 17.8 20.2 3.7 7.1 14.9 25.7 38.0 10.6 16.8 11.2 11.7 SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.4;Hofbauer cells: 36.5;Kupffer cells: 22.0;Macrophages: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cell line enhanced" "Detected in many" "A-431: 33.8;CAPAN-2: 70.3;hTCEpi: 34.9;hTERT-HME1: 64.8;U-138 MG: 47.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" 4.2 24.2 1.7 16.9 2.6 1.4 4.6 2.4 3.7 2.3 2.1 8.0 9.1 1.0 1.3 13.4 1.2 5.1 1.5 1.9 2.3 0.7 5.9 5.9 5.7 4.3 2.7 1.0 1.2 1.1 0.2 7.4 3.8 2.6 10.2 0.5 78.8 1.4 0.6 20.9 7.7 3.1 3.2 15.8 2.1 1.6 5.2 2.1 0.6 0.9 5.1 11.9 7.7 7.3 33.8 0.1 1.0 0.4 0.6 0.8 0.6 1.6 2.8 1.0 2.5 0.2 70.3 0.4 9.4 0.4 2.5 21.0 0.4 20.9 3.8 0.9 0.6 6.6 1.6 2.4 0.1 0.3 0.9 0.7 34.9 2.6 64.8 2.7 1.7 1.3 0.5 2.2 3.1 0.3 0.3 4.6 1.9 0.2 1.0 0.4 2.7 0.8 1.0 17.6 0.3 0.3 4.8 2.9 2.6 0.5 0.3 1.8 3.7 47.2 1.9 0.7 1.6 1.8 1.5 1.1 1.7 2.4 4.1 0.2 12.3 0.0 0.0 14.1 0.0 0.4 0.0 0.1 5.5 0.1 0.1 0.1 1.3 0.0 19.2 0.2 0.0 5.4 1.7 2.6 2.4 3.7 1.9 2.3 4.3 2.7 3.8 3.2 5.2 7.3 0.7 0.0 0.6 0.3 3.8 0.3 1.4 0.5 1.2 1.5 1.4 1.1 1.1 1.5 1.6 0.0 2.1 0.6 0.7 13.4 0.0 0.1 1.6 1.9 1.4 1.3 0.0 2.7 0.3 0.0 0.8 0.5 0.0 4.9 2.5 0.4 1.8 0.3 36.5 0.0 0.3 0.1 0.0 22.0 1.4 2.2 0.9 22.7 0.0 8.4 7.3 0.3 3.1 1.0 0.2 0.1 3.3 1.2 1.7 1.0 0.0 0.1 0.2 0.8 0.0 0.8 0.6 2.7 1.1 5.7 0.9 3.4 1.2 0.4 0.1 3.2 SLC38A6 NAT-1 ENSG00000139974 "Solute carrier family 38 member 6" Q8IZM9 14 60981114-61083733 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 178.2;Excitatory neurons: 98.8;Hofbauer cells: 100.3;Inhibitory neurons: 77.4;Late spermatids: 124.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018508 Approved Approved "Plasma membrane,Cell Junctions,Microtubules" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Plasma membrane, Microtubules" "HPA018508: AB_2190518" "unprognostic (7.08e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (9.47e-6)" "unprognostic (9.89e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-2)" "unprognostic (2.20e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (1.37e-5)" "unprognostic (1.73e-1)" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" 7.6 9.1 6.0 4.7 6.6 2.9 7.4 6.1 9.5 7.3 8.9 4.8 3.1 5.1 13.2 3.3 5.6 9.9 3.7 6.9 6.5 12.0 6.3 8.6 7.8 5.4 6.0 5.8 3.4 21.3 7.2 9.6 6.0 5.1 6.6 7.5 5.9 3.9 2.1 2.9 3.5 5.3 5.0 6.6 3.8 5.0 7.4 5.0 6.3 3.0 4.8 7.0 5.0 6.7 16.2 21.5 6.8 12.3 68.7 25.3 4.9 11.6 34.5 10.7 10.2 5.4 41.0 4.0 19.2 10.6 22.5 13.5 6.8 11.9 9.8 6.0 3.2 6.7 8.6 14.2 22.7 3.7 12.1 19.9 4.9 10.5 12.2 43.2 14.3 6.8 9.3 8.4 37.5 9.2 6.6 8.4 4.0 9.5 14.3 1.6 20.1 11.9 30.7 8.5 3.3 3.0 9.9 7.0 19.1 9.3 10.4 5.8 15.6 16.4 7.1 20.0 6.5 1.6 4.9 1.6 34.0 3.0 13.1 0.0 6.6 0.1 1.7 7.1 2.2 2.2 3.1 2.4 3.6 2.0 2.7 3.4 0.2 0.8 4.5 4.4 4.5 2.8 6.0 6.6 6.1 9.5 6.9 6.5 5.4 6.0 6.0 5.0 7.4 6.7 6.8 22.4 6.7 31.6 6.0 5.2 11.4 14.6 8.0 19.7 7.2 7.5 4.3 7.2 10.0 5.5 22.9 5.6 4.9 2.6 1.9 5.3 178.2 13.0 11.0 7.2 4.2 3.4 98.8 2.8 9.4 11.2 5.1 6.2 6.3 7.3 4.2 4.6 100.3 5.0 77.4 3.1 6.1 24.8 10.0 124.4 10.8 26.2 5.4 20.6 6.4 11.7 2.1 54.3 30.8 7.4 1.9 6.0 5.8 6.6 3.3 23.1 40.4 24.9 0.0 12.3 9.1 16.6 11.5 6.4 2.8 6.7 7.8 5.0 2.8 6.9 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC46A1 "HCP1, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 93.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Hepatocytes: 27.8;Hofbauer cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "CACO-2: 205.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "CAB011614: AB_2270597" "unprognostic (1.10e-1)" "unprognostic (8.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (9.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-3)" "unprognostic (6.15e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" 6.7 24.8 8.1 5.7 10.6 3.4 5.7 14.7 9.2 5.6 26.7 5.7 93.9 4.6 8.5 2.4 13.4 4.6 4.6 8.0 8.4 7.5 27.3 6.9 5.5 11.2 9.7 8.7 11.2 15.0 15.5 8.2 10.4 7.4 5.6 8.7 12.5 9.0 3.6 2.3 40.5 5.5 9.8 11.1 5.5 3.1 10.0 23.4 6.4 2.8 2.1 5.0 2.6 12.1 5.4 22.5 7.4 12.2 5.9 1.3 22.9 6.3 4.6 5.1 5.7 205.4 6.4 0.4 3.6 3.4 14.8 17.3 8.4 14.1 4.3 13.1 19.6 0.2 14.0 17.6 2.1 0.1 10.1 2.8 25.3 5.3 15.8 7.1 0.4 1.8 8.9 1.2 0.9 7.2 0.1 0.6 4.4 5.2 2.9 0.3 6.0 2.7 4.0 11.8 19.4 10.2 43.6 20.1 2.4 10.1 15.6 3.4 0.6 0.8 8.6 1.2 6.6 9.0 11.1 0.3 1.2 1.3 4.7 5.2 0.9 0.6 0.4 3.0 0.7 1.6 0.4 0.3 1.4 0.8 0.5 0.8 1.0 1.6 2.6 0.5 0.9 0.5 8.1 10.6 14.7 9.2 8.0 8.4 11.2 9.7 10.4 9.8 10.0 12.1 1.2 12.8 5.3 7.5 1.0 0.4 1.9 2.8 4.0 26.6 5.1 6.1 2.3 17.2 2.2 7.3 4.2 20.8 0.2 3.7 0.0 3.5 3.6 18.2 1.8 1.9 1.2 0.4 2.8 4.6 9.7 3.6 3.1 1.5 1.3 4.2 1.8 27.8 25.7 20.2 4.6 2.4 0.0 21.5 1.0 19.5 4.1 8.0 0.0 5.6 2.0 2.2 0.0 8.0 6.9 3.8 3.6 3.4 3.0 2.6 3.9 4.6 4.3 6.0 6.6 3.7 1.4 0.3 0.3 1.2 0.3 4.4 0.6 5.8 1.3 1.6 SLC49A3 "FLJ22269, LP2561, MFSD7" ENSG00000169026 "Solute carrier family 49 member 3" Q6UXD7 4 681829-689271 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 12.8;Breast glandular cells: 14.6;Collecting duct cells: 14.7;Ductal cells: 19.2;Extravillous trophoblasts: 33.9;Hofbauer cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 8.7;CAPAN-2: 5.8;SK-BR-3: 8.2;T-47d: 25.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043593 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "HPA043593: AB_10959611" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (8.77e-2)" "unprognostic (4.70e-2)" "unprognostic (9.40e-2)" "unprognostic (1.84e-3)" "unprognostic (2.22e-1)" "unprognostic (1.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.56e-1)" "unprognostic (9.22e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.66e-5)" "unprognostic (8.35e-2)" "unprognostic (4.92e-2)" "unprognostic (7.48e-2)" "unprognostic (1.11e-1)" 8.2 3.2 2.4 4.4 2.1 3.5 9.0 2.7 3.0 4.5 3.5 4.2 5.9 3.4 4.2 4.4 3.3 3.7 8.3 1.7 2.3 8.3 5.8 8.1 3.0 3.2 2.2 1.2 4.8 4.6 1.9 2.7 3.0 5.0 2.3 12.6 8.4 2.1 3.0 10.2 5.9 2.1 2.7 8.5 8.4 8.9 3.5 0.6 8.5 1.9 1.7 4.3 4.9 2.9 0.1 0.1 2.7 1.9 1.9 3.7 8.7 1.0 0.0 0.7 0.6 0.4 5.8 0.1 0.2 4.5 0.4 0.2 0.0 0.0 0.2 0.6 0.6 1.6 0.7 0.2 0.8 0.0 1.2 2.5 0.0 3.4 0.0 0.0 1.3 0.3 0.4 0.5 0.0 0.1 0.1 0.7 0.3 0.4 0.5 0.0 0.3 0.6 0.0 0.3 0.9 0.7 0.0 8.2 0.5 0.5 25.8 1.6 0.3 0.8 0.3 0.4 0.3 2.8 1.6 0.1 0.3 0.7 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.4 0.2 0.0 0.1 0.3 2.4 2.1 2.7 3.0 1.7 2.3 3.2 2.2 3.0 2.7 3.5 2.9 12.8 3.2 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.6 8.4 0.0 0.0 1.8 14.7 0.0 0.7 3.1 0.0 1.9 19.2 0.0 2.1 6.0 4.3 0.0 0.0 0.0 0.4 33.9 4.3 0.0 4.1 0.0 0.8 0.0 0.0 35.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 4.9 0.7 0.5 0.0 0.0 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SNX24 SBBI31 ENSG00000064652 "Sorting nexin 24" Q9Y343 5 122843439-123029354 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044566, HPA073934" Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA044566: AB_10797034, HPA073934: AB_2686644" "unprognostic (2.63e-1)" "unprognostic (2.50e-1)" "unprognostic (2.73e-1)" "prognostic unfavorable (7.93e-6)" "unprognostic (2.31e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (8.88e-4)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (3.42e-1)" "unprognostic (5.77e-2)" "unprognostic (3.69e-2)" "prognostic favorable (1.28e-4)" "unprognostic (2.03e-1)" "unprognostic (1.10e-1)" "unprognostic (6.94e-2)" "unprognostic (1.50e-2)" 8.1 8.1 12.3 5.5 15.1 4.5 7.5 19.0 15.5 9.5 13.1 11.1 15.2 6.5 11.8 36.8 7.6 10.5 12.3 11.4 15.6 20.6 14.1 17.3 6.5 19.3 15.6 5.9 10.6 25.6 7.8 25.3 18.6 6.1 12.5 12.5 12.3 6.5 9.5 16.8 11.5 11.0 16.9 7.7 16.4 8.7 17.1 2.5 18.5 14.0 8.8 9.2 14.2 23.9 33.2 14.7 23.5 15.8 8.5 21.7 47.2 28.7 26.7 32.9 42.1 20.8 30.0 0.0 24.0 28.3 31.9 6.7 15.2 36.8 50.3 17.8 9.3 4.7 13.4 29.8 43.4 0.2 5.4 18.3 53.4 16.6 64.4 28.5 16.0 5.7 6.1 26.3 25.1 29.5 0.8 1.3 9.6 6.0 9.3 4.2 37.3 16.3 47.8 19.8 14.4 17.2 27.1 19.7 31.2 30.4 35.5 10.4 13.9 35.4 27.3 14.0 46.6 9.1 12.9 5.0 30.3 0.6 73.4 0.0 1.4 0.0 0.6 2.8 0.3 0.3 0.6 0.5 0.7 0.2 0.2 0.1 0.0 1.3 3.2 0.1 1.4 0.5 12.3 15.1 19.0 15.5 11.4 15.6 19.3 15.6 18.6 16.9 17.1 23.9 7.8 44.8 24.6 45.4 1.1 10.5 7.5 10.6 3.4 18.3 8.7 5.8 14.9 14.3 6.3 20.2 6.2 45.1 3.7 17.7 35.2 15.6 75.8 18.6 11.1 6.5 1.2 4.0 51.8 11.8 57.1 12.6 7.1 15.0 0.0 19.1 8.6 12.9 66.1 11.8 52.1 6.7 6.1 51.9 4.7 95.9 9.0 21.0 3.6 60.9 16.0 12.4 4.1 46.8 63.5 21.9 4.4 9.4 2.7 16.2 35.2 39.9 12.0 18.0 13.1 7.0 9.1 5.0 9.6 19.5 16.8 39.7 3.9 39.2 8.9 11.8 SOAT1 "ACAT, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 165.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: AB_2679967" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" 14.6 165.3 4.2 18.1 5.7 17.5 8.2 5.5 6.6 13.7 9.0 13.0 12.2 11.7 6.6 4.8 17.9 20.5 5.4 3.3 6.8 12.7 14.1 20.9 15.1 10.1 6.1 10.7 27.0 13.4 6.3 19.1 8.0 27.7 14.8 10.3 39.4 9.3 4.0 5.7 12.7 16.5 8.0 15.1 16.3 11.0 6.7 8.1 9.2 3.7 13.1 11.7 4.5 12.8 74.6 34.1 27.7 41.0 104.7 56.6 147.3 35.1 61.7 76.2 88.3 35.2 82.6 42.0 53.9 64.4 92.6 26.8 88.6 20.9 81.8 48.0 18.2 19.5 26.7 36.9 42.9 33.5 7.5 45.4 13.3 89.2 75.8 32.1 33.3 50.5 42.7 21.0 120.0 15.9 35.9 10.8 13.4 11.8 11.2 44.4 35.8 24.4 66.1 45.9 8.4 21.5 54.3 22.9 20.1 32.3 24.0 22.8 31.9 89.8 43.1 99.5 78.2 29.4 115.3 35.5 35.7 17.9 170.6 55.4 53.4 1.6 26.4 34.2 25.0 12.9 24.0 24.8 48.9 10.4 23.0 23.3 39.3 37.9 23.7 8.8 33.2 32.5 4.2 5.7 5.5 6.6 3.3 6.8 10.1 6.1 8.0 8.0 6.7 12.8 14.9 22.4 33.4 11.4 16.0 9.9 10.1 11.3 8.0 7.3 7.2 4.6 8.5 30.0 14.5 20.2 14.6 17.6 21.2 16.0 1.9 42.5 29.5 34.9 32.8 16.0 59.9 9.0 12.1 25.0 51.6 21.3 18.3 34.5 14.0 9.2 15.4 24.2 70.3 6.7 15.0 25.5 22.4 77.4 41.9 14.5 32.6 74.9 23.2 29.0 55.4 7.6 19.6 10.6 7.3 20.3 13.3 25.9 17.7 26.7 8.7 14.9 46.2 14.5 26.3 9.2 13.5 6.8 9.7 5.0 5.3 8.8 24.8 44.3 15.5 8.5 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 SPP1 "BNSP, BSPI, ETA-1, OPN" ENSG00000118785 "Secreted phosphoprotein 1" P10451 4 87975650-87983426 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Biomineralization, Cell adhesion" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 2424.4;kidney: 3587.6;placenta: 2791.9" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 60702.5" "Group enriched" "Detected in all" 4 "glioma: 1690.9;renal cancer: 1385.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "neutrophil: 24.8" "Lineage enriched" "Detected in single" 249 "granulocytes: 24.8" "Cell line enhanced" "Detected in many" "EFO-21: 4825.8;Hep G2: 2469.7;RPTEC TERT1: 10348.3" "Region enhanced" "Detected in all" "pons and medulla: 316.8" "Low region specificity" "Detected in all" "HPA027540, HPA027541" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 114000000 73000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "HPA027540: AB_10600222, HPA027541: AB_10601446" "unprognostic (4.74e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.13e-3)" "unprognostic (2.04e-1)" "unprognostic (2.31e-2)" "unprognostic (6.96e-3)" "prognostic unfavorable (2.84e-6)" "unprognostic (2.46e-3)" "unprognostic (7.86e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (4.31e-2)" "unprognostic (2.55e-1)" "unprognostic (7.19e-2)" "unprognostic (1.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.63e-2)" 113.1 24.4 276.0 59.5 490.3 1.0 70.2 652.0 736.4 27.5 265.0 44.9 9.5 131.2 9.8 4.8 52.8 2424.4 37.0 301.6 417.1 3587.6 35.6 18.8 9.1 813.2 645.3 9.9 292.0 19.2 20.6 2791.9 781.8 15.7 7.6 745.5 88.7 22.1 16.0 2.7 14.4 38.3 472.6 9.2 11.0 11.7 633.1 8.4 8.3 0.4 5.7 25.0 6.0 855.0 2.2 144.0 19.1 1.1 0.0 0.2 0.3 5.6 4.4 1.4 9.1 0.6 0.2 0.2 4825.8 2.3 371.5 1.4 0.0 0.0 3.1 11.2 0.0 0.0 1.8 2469.7 0.3 6.8 5.1 0.5 0.3 34.9 0.1 118.8 4.2 0.2 0.1 10.8 1.3 0.2 1.2 21.3 227.5 0.3 0.0 2.4 0.5 1189.8 10348.3 1.8 1.1 0.9 0.3 0.8 339.1 441.9 0.5 5.2 0.3 11.5 27.1 0.4 25.8 0.9 7.9 13.9 436.3 1.1 457.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 276.0 490.3 652.0 736.4 301.6 417.1 813.2 645.3 781.8 472.6 633.1 855.0 35.7 3.2 4.7 5.2 34.0 1.5 5.2 0.1 1.2 46.6 1767.7 22.4 17.9 1584.2 0.3 2183.1 27.1 335.6 6.9 0.0 1003.7 7273.8 0.1 61.2 25.2 367.9 0.0 2.7 1.4 71.7 294.5 48.9 0.0 154.2 0.0 1.7 5.7 5.0 60702.5 785.7 9.9 0.0 0.0 57.4 7.7 1.0 0.9 247.7 1.8 99.3 69.2 3862.9 0.0 4.5 532.1 215.4 0.0 0.0 0.1 0.4 0.0 5594.0 1.6 169.7 0.0 0.9 21.6 0.5 0.2 1.1 1.0 667.8 30.0 0.4 0.0 9.9 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STX6 ENSG00000135823 "Syntaxin 6" O43752 1 180972712-181023121 "Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038557, HPA038558" Approved Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Nucleoplasm "HPA038557: AB_2676082, HPA038558: AB_10672716" "unprognostic (1.11e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (9.09e-3)" "unprognostic (2.23e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.12e-1)" "unprognostic (6.12e-2)" "unprognostic (4.48e-3)" "unprognostic (4.18e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.93e-8)" "unprognostic (2.59e-1)" "unprognostic (1.59e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" 9.5 7.4 13.7 11.2 14.9 2.7 9.2 15.9 17.9 9.5 11.6 7.9 7.5 8.2 7.7 17.5 7.4 7.1 5.8 15.6 13.5 8.7 4.8 11.3 10.9 13.8 13.7 8.2 4.1 7.4 4.5 11.5 12.6 7.2 8.1 8.1 8.0 6.7 4.0 12.8 7.6 8.7 13.2 9.3 7.9 5.6 14.1 17.2 11.4 4.9 14.1 14.2 11.2 16.6 16.9 18.6 18.0 24.1 18.5 21.7 30.3 21.2 27.3 16.4 13.9 17.4 16.5 17.0 28.7 23.4 10.2 29.4 16.5 37.4 19.0 12.3 12.1 11.4 14.2 17.2 18.4 16.4 14.1 19.9 33.6 27.6 28.3 29.3 33.6 15.7 21.3 11.8 22.0 24.2 15.9 15.4 28.2 21.0 9.2 13.7 22.0 24.7 19.6 41.7 25.5 27.0 22.2 42.3 23.9 30.7 25.8 14.9 28.0 22.4 11.8 21.2 17.3 19.8 11.8 12.3 11.0 15.8 13.5 2.6 1.6 2.1 0.7 1.3 0.8 0.7 1.1 1.1 2.2 0.7 1.4 0.9 1.4 0.2 1.1 0.7 1.4 0.6 13.7 14.9 15.9 17.9 15.6 13.5 13.8 13.7 12.6 13.2 14.1 16.6 13.9 16.0 18.6 32.3 11.8 48.9 21.3 19.0 41.5 12.8 16.0 11.7 6.4 2.8 13.7 18.4 6.2 25.7 15.8 10.5 11.7 10.7 8.9 19.4 16.6 23.0 23.4 16.0 54.7 9.8 24.9 12.7 19.4 22.7 12.0 12.7 14.6 4.8 26.4 8.4 38.0 11.1 16.2 26.1 28.0 11.8 8.4 31.9 7.2 23.4 25.2 6.7 15.5 50.3 30.7 14.9 13.9 13.2 10.0 22.2 10.2 11.5 13.3 11.4 6.6 8.2 12.2 5.6 15.4 47.8 37.6 20.5 14.0 16.4 10.6 22.8 SUMF1 "FGE, UNQ3037" ENSG00000144455 "Sulfatase modifying factor 1" Q8NBK3 3 3700814-4467273 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 116.4;hTERT-RPE1: 117.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038025 Uncertain "Intracellular and membrane" NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA038025: AB_10675624" "unprognostic (5.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.08e-1)" "unprognostic (8.99e-3)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (8.34e-3)" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.65e-2)" "unprognostic (2.28e-1)" "prognostic favorable (4.79e-7)" "unprognostic (5.12e-2)" "unprognostic (2.58e-1)" "unprognostic (1.45e-1)" "unprognostic (7.86e-2)" 20.7 19.5 10.4 13.1 12.0 10.2 29.2 10.9 12.2 21.3 15.6 23.9 13.3 15.8 26.8 28.7 25.6 19.7 12.5 10.2 12.2 39.3 27.4 23.0 12.6 12.2 11.7 17.4 18.9 46.8 14.5 18.8 11.4 22.1 29.6 3.4 22.8 17.7 4.3 20.3 14.1 20.5 11.4 16.8 23.8 5.1 13.1 10.6 28.4 7.6 13.4 20.0 18.5 13.1 25.0 20.6 11.4 6.3 116.4 61.3 21.9 34.4 53.9 16.2 18.2 9.6 78.9 3.7 20.3 63.0 24.3 13.3 5.0 39.0 25.2 12.0 10.1 5.4 18.9 26.2 30.0 6.1 14.4 56.6 43.2 18.2 5.3 117.9 44.8 8.9 9.1 8.4 45.8 40.2 3.4 9.1 12.0 22.8 23.4 6.3 17.0 16.0 86.6 28.0 2.2 12.6 24.6 56.8 20.4 19.5 75.7 15.6 41.4 32.5 4.2 25.3 21.0 10.4 22.8 1.7 63.2 13.5 24.7 66.1 100.5 35.6 38.9 81.8 35.2 26.6 31.2 32.9 86.6 30.7 39.4 32.0 36.2 42.0 78.2 45.9 16.9 90.2 10.4 12.0 10.9 12.2 10.2 12.2 12.2 11.7 11.4 11.4 13.1 13.1 12.8 19.2 20.1 36.9 13.8 12.7 18.8 32.9 21.1 5.6 29.5 23.2 5.5 18.6 16.7 38.6 6.2 29.8 9.7 16.5 11.7 39.3 26.1 14.2 14.1 13.7 8.4 11.1 53.2 19.1 23.3 25.8 21.4 21.9 17.1 10.4 17.5 18.7 28.2 3.3 57.0 19.7 4.1 37.1 12.0 10.7 16.4 24.3 19.6 62.8 43.9 6.8 11.3 56.8 85.5 14.0 16.4 17.3 11.5 13.7 10.5 23.8 19.4 6.2 6.6 21.2 16.5 4.8 5.1 25.9 11.8 24.4 11.6 11.1 25.6 18.3 TBC1D2 "Armus, PARIS1, TBC1D2A" ENSG00000095383 "TBC1 domain family member 2" Q9BYX2 9 98199011-98255649 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 77.0;HaCaT: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030871, HPA076521" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA030871: AB_10670046, HPA076521: " "unprognostic (2.32e-2)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (9.21e-3)" "unprognostic (6.40e-3)" "unprognostic (2.30e-1)" "unprognostic (6.07e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.30e-2)" "unprognostic (4.30e-1)" 8.8 5.3 11.1 5.7 16.0 13.1 7.8 12.3 26.0 10.8 8.5 8.6 12.6 4.4 1.5 37.4 5.5 4.0 3.7 10.6 12.9 6.4 19.8 32.0 3.8 14.9 14.9 2.9 3.0 3.5 4.4 7.2 16.4 12.0 4.4 3.4 14.7 6.1 4.3 24.3 10.1 2.8 11.4 9.4 7.0 3.4 23.3 3.0 8.1 1.4 4.9 11.7 17.3 23.9 77.0 10.8 0.5 2.5 8.2 15.9 24.3 33.2 18.4 23.8 19.6 6.9 32.8 1.3 24.7 19.6 5.2 98.1 0.7 36.8 8.3 2.6 1.4 0.7 38.0 5.4 37.6 1.7 2.9 21.7 59.8 23.6 58.7 41.5 8.6 2.1 2.4 1.0 19.0 9.9 0.4 4.6 1.6 7.4 6.2 1.2 4.8 0.2 36.0 46.7 0.9 1.4 11.3 24.4 3.4 1.7 8.1 2.6 51.7 28.8 8.6 4.8 13.6 1.6 1.5 0.6 29.0 2.9 3.2 2.1 27.5 8.4 2.5 15.3 1.8 1.2 3.8 2.2 10.0 0.8 1.6 1.9 11.9 1.2 12.3 1.3 5.5 10.8 11.1 16.0 12.3 26.0 10.6 12.9 14.9 14.9 16.4 11.4 23.3 23.9 2.9 57.7 12.5 5.2 2.4 8.3 18.5 30.4 21.6 3.3 2.7 5.6 0.7 4.3 23.3 3.7 0.0 21.5 0.9 16.2 3.9 3.3 1.8 4.6 3.7 5.0 7.7 0.4 4.6 3.2 10.9 2.4 6.1 10.3 0.0 0.6 1.1 6.1 32.0 1.7 5.4 12.6 18.3 16.2 1.8 1.2 1.8 18.3 3.6 4.7 7.5 4.4 3.1 12.1 64.9 14.4 10.7 0.7 1.7 9.2 16.4 3.2 10.8 2.4 0.0 1.8 3.4 2.1 3.0 29.8 10.9 17.4 2.4 0.7 5.7 17.1 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TBXT T ENSG00000164458 "T-box transcription factor T" O15178 6 166157656-166168700 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "parathyroid gland: 2.6;pituitary gland: 1.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "testis cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA003322 Uncertain Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA003322: AB_1080176" "unprognostic (5.68e-2)" "unprognostic (4.59e-2)" "unprognostic (6.21e-3)" "unprognostic (8.64e-3)" "unprognostic (9.34e-3)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 16.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 45.5;Kupffer cells: 56.3;Macrophages: 61.6;Microglial cells: 60.0;monocytes: 44.1;Proximal tubular cells: 77.8" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Cell line enhanced" "Detected in some" "HEL: 15.9;HUVEC TERT2: 11.0;THP-1: 21.5;TIME: 12.5;U-937: 24.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA063577" Approved Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB032260: AB_2202845, HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" 3.5 2.4 1.3 19.2 1.2 17.2 2.6 1.5 1.6 1.9 2.1 2.7 4.2 1.4 0.6 1.0 1.0 4.9 1.0 0.8 1.7 20.5 3.1 9.9 22.1 3.3 1.9 1.3 1.0 0.4 0.6 4.7 2.7 1.0 4.2 0.1 1.3 0.9 0.3 0.4 9.7 3.1 2.7 14.6 3.0 1.6 3.7 2.8 0.9 0.4 12.6 4.0 0.6 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 1.7 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 21.5 12.5 2.1 0.2 1.3 0.0 5.5 0.0 0.0 0.1 24.4 1.1 0.0 7.1 0.0 0.0 2.8 0.0 3.8 0.0 0.0 6.3 2.5 0.0 0.0 0.1 0.0 0.4 3.3 0.0 1.5 1.3 1.2 1.5 1.6 0.8 1.7 3.3 1.9 2.7 2.7 3.7 4.8 0.5 0.0 2.2 0.3 18.1 0.5 0.0 0.0 0.0 0.0 0.3 0.8 0.8 1.5 0.0 3.7 0.0 0.2 8.3 0.0 0.0 0.0 2.4 0.0 0.0 1.7 0.0 7.2 0.6 0.0 0.3 0.4 0.0 0.0 2.5 0.0 0.0 0.0 45.5 0.0 0.5 0.4 0.0 56.3 17.8 3.8 0.0 61.6 0.0 60.0 44.1 0.0 1.0 1.0 0.1 0.1 0.0 0.0 1.3 0.1 15.6 77.8 0.0 0.0 0.0 0.3 0.1 0.3 2.5 0.1 0.4 0.8 0.8 0.1 0.7 0.1 TFPT "amida, FB1, INO80F" ENSG00000105619 "TCF3 fusion partner" P0C1Z6 19 54107020-54115657 "Disease related genes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034958, HPA058534" Approved Supported Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA034958: AB_10603036, HPA058534: AB_2683745" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (5.13e-4)" "unprognostic (6.56e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.85e-1)" "unprognostic (2.85e-1)" "unprognostic (2.71e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.80e-2)" "unprognostic (1.15e-1)" "unprognostic (2.00e-2)" "unprognostic (2.61e-1)" "unprognostic (3.43e-1)" "unprognostic (3.66e-2)" 12.1 15.8 27.4 8.9 25.2 10.4 12.8 23.1 41.3 11.7 18.6 15.7 9.7 11.7 4.3 10.0 9.9 7.2 16.1 26.5 24.7 12.0 10.5 12.3 10.7 24.1 25.0 9.5 8.7 9.2 10.9 8.4 24.3 22.2 4.1 5.0 13.1 5.4 19.4 13.2 12.2 6.1 20.9 19.1 14.1 9.1 24.0 13.5 11.2 10.6 6.4 12.3 9.4 28.0 23.5 28.5 18.2 12.9 6.7 9.5 11.8 25.1 15.5 23.9 24.5 17.8 23.6 20.5 20.2 12.8 12.5 11.2 10.8 19.6 7.8 43.5 52.2 30.7 27.5 20.8 39.6 16.1 34.7 11.2 9.5 18.8 15.7 11.5 18.7 30.8 19.3 45.8 9.2 30.2 34.3 47.2 11.0 34.1 19.8 30.6 10.0 15.4 10.0 35.9 19.2 17.4 9.2 38.4 45.1 5.6 14.0 48.9 37.8 52.4 19.3 7.5 36.9 33.8 48.2 18.5 20.7 40.4 34.4 10.5 9.2 6.4 15.4 10.7 14.6 9.4 19.4 20.1 19.0 9.3 16.2 17.2 6.5 21.4 3.9 43.3 26.0 11.2 27.4 25.2 23.1 41.3 26.5 24.7 24.1 25.0 24.3 20.9 24.0 28.0 25.3 16.0 7.2 5.2 12.2 17.0 9.8 25.5 12.0 10.9 31.4 32.3 2.5 12.8 28.6 22.0 2.1 22.4 30.3 22.5 15.6 21.0 9.6 27.1 8.2 29.5 15.6 7.8 5.0 27.6 29.1 11.3 11.2 13.3 15.2 20.8 37.9 9.6 135.7 0.0 4.1 35.7 32.6 28.1 41.0 5.5 12.2 43.5 39.2 1.0 49.7 17.8 25.7 2.5 3.6 55.9 18.4 17.0 13.1 31.9 23.0 24.8 46.4 12.4 6.6 7.8 16.5 11.0 16.0 5.8 17.3 26.1 22.8 41.1 16.1 13.0 TIGAR C12orf5 ENSG00000078237 "TP53 induced glycolysis regulatory phosphatase" Q9NQ88 12 4307763-4360028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034010, HPA040354, HPA044111" Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB034010: AB_1128227, HPA040354: AB_2676935, HPA044111: AB_2678814" "unprognostic (1.76e-1)" "unprognostic (6.33e-2)" "unprognostic (4.08e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.41e-2)" "unprognostic (2.11e-1)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.21e-2)" "unprognostic (2.03e-2)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" 3.8 5.4 1.4 1.9 1.6 1.9 2.9 1.9 3.0 1.8 1.8 3.7 0.7 2.8 1.2 3.7 2.3 1.4 5.0 2.2 1.6 4.2 3.1 3.7 2.0 1.9 2.0 1.1 2.0 0.9 5.3 1.4 2.1 2.8 1.7 2.3 3.0 1.7 5.8 2.5 3.6 2.1 2.1 5.3 3.3 3.5 1.9 1.7 2.3 2.0 1.9 3.5 2.4 2.3 4.1 9.9 4.8 7.7 10.9 6.3 47.3 9.3 8.0 5.3 7.3 5.7 3.8 4.1 0.7 5.8 5.2 5.7 5.8 7.6 7.0 3.8 2.9 0.1 4.7 7.8 14.3 2.1 0.5 8.1 12.9 5.9 6.8 3.2 14.5 3.4 0.3 2.2 9.2 7.7 2.2 0.8 8.6 5.5 1.7 3.0 6.4 1.0 6.7 5.0 0.2 2.8 7.9 3.2 10.1 22.0 0.8 1.6 10.5 8.2 5.9 5.6 3.8 1.4 2.1 6.9 5.4 0.8 5.7 0.5 1.7 0.2 0.7 3.5 0.5 0.9 0.7 0.8 1.9 1.3 0.6 0.7 1.5 0.8 3.4 1.6 1.4 0.6 1.4 1.6 1.9 3.0 2.2 1.6 1.9 2.0 2.1 2.1 1.9 2.3 10.7 0.0 1.7 0.0 14.7 0.0 13.8 0.0 5.7 4.2 6.2 7.5 10.5 1.5 0.0 5.5 18.8 27.4 16.9 5.0 15.6 15.6 28.0 4.7 5.9 9.4 7.3 1.3 0.0 13.9 28.5 6.6 11.7 4.8 0.0 4.5 5.0 5.6 59.3 1.7 0.0 1.5 0.0 20.4 0.0 27.8 3.7 30.6 0.0 0.0 34.9 11.5 7.2 0.0 0.0 17.5 2.6 4.5 16.3 9.5 2.9 11.7 0.0 3.3 6.6 5.7 8.3 19.9 22.3 8.1 0.0 34.3 11.8 10.8 2.3 15.6 TLR5 "FLJ10052, MGC126430, MGC126431, SLEB1, TIL3" ENSG00000187554 "Toll like receptor 5" O60602 1 223109404-223143248 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 20.2" "Cell type enhanced" "Detected in many" "Club cells: 23.3;Glandular and luminal cells: 25.6;Kupffer cells: 29.5;Microglial cells: 23.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 30.8;intermediate monocyte: 28.1;myeloid DC: 23.4;neutrophil: 25.3;non-classical monocyte: 12.4" "Group enriched" "Detected in many" 11 "dendritic cells: 23.4;granulocytes: 25.3;monocytes: 30.8" "Cell line enhanced" "Detected in some" "A-431: 2.1;HaCaT: 3.2;OE19: 1.8;SK-BR-3: 2.0;T-47d: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009013 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB009013: AB_2240732" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-2)" "unprognostic (3.81e-2)" "unprognostic (3.09e-2)" "unprognostic (6.83e-2)" "unprognostic (1.49e-2)" "unprognostic (2.71e-1)" "unprognostic (4.23e-3)" "unprognostic (1.46e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (1.06e-3)" "unprognostic (5.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" 3.5 1.9 2.6 4.7 2.2 0.5 8.6 2.5 2.4 6.0 2.3 2.0 1.6 2.1 2.6 4.9 5.1 4.5 1.7 2.3 2.7 4.1 1.6 6.2 4.3 3.7 3.5 20.2 4.0 4.4 0.7 3.4 3.6 3.3 2.1 0.7 10.3 2.4 1.4 2.0 2.1 2.6 3.1 2.9 4.1 1.8 3.4 2.5 1.9 1.6 5.0 4.0 2.4 5.0 2.1 0.2 0.3 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.0 3.2 0.0 0.2 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.2 0.1 0.8 0.4 0.0 0.0 0.3 0.5 0.1 1.1 1.8 0.0 0.0 0.0 0.1 0.9 0.4 0.8 0.3 0.6 2.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.3 0.2 0.0 30.8 0.4 0.2 28.1 0.4 0.2 1.5 0.4 23.4 0.1 2.3 0.7 25.3 0.4 12.4 0.3 1.2 10.9 2.6 2.2 2.5 2.4 2.3 2.7 3.7 3.5 3.6 3.1 3.4 5.0 1.0 3.2 17.0 0.0 0.2 0.5 5.8 18.9 4.6 0.1 10.6 5.3 1.7 14.3 23.3 22.0 2.1 1.5 0.3 0.4 3.9 5.9 4.6 13.6 2.0 2.1 1.2 0.0 0.5 3.8 0.3 7.7 3.1 25.6 2.5 4.6 0.7 0.7 18.1 0.0 1.0 0.6 6.1 29.5 3.1 5.7 9.3 22.4 3.6 23.4 14.4 1.4 0.0 1.5 0.1 2.4 0.1 8.6 0.1 3.0 0.5 0.1 11.0 0.2 0.0 4.2 4.1 5.4 5.5 15.9 1.6 0.8 1.7 4.1 1.5 6.3 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM4SF19 ENSG00000145107 "Transmembrane 4 L six family member 19" Q96DZ7 3 196319342-196338503 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.0;testis: 4.6" "Cell type enriched" "Detected in some" 8 "Hofbauer cells: 74.6" "Group enriched" "Detected in some" 4 "cervical cancer: 1.4;head and neck cancer: 3.4;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 0.9" "Region enhanced" "Detected in single" "thalamus: 2.5" "Group enriched" "Detected in some" 6 "gdT-cell: 14.8;memory CD8 T-cell: 3.9;naive CD8 T-cell: 4.9" "Lineage enriched" "Detected in single" 16 "T-cells: 14.8" "Cell line enriched" "Detected in many" 12 "GAMG: 427.6" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 71: Testis - DNA repair" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (9.90e-2)" "unprognostic (1.17e-2)" "unprognostic (3.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.67e-1)" "unprognostic (7.19e-2)" "unprognostic (8.90e-5)" "unprognostic (8.86e-3)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.85e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-3)" "unprognostic (4.23e-2)" "unprognostic (4.20e-3)" "unprognostic (2.60e-1)" "unprognostic (1.18e-3)" 6.0 0.3 0.1 0.5 0.2 0.6 2.9 0.3 0.5 1.5 0.0 0.3 0.2 0.3 0.0 3.4 0.3 0.1 0.1 0.2 0.1 0.2 0.5 3.5 0.5 0.1 0.2 0.7 0.3 0.0 0.1 0.8 0.4 0.5 0.2 0.5 1.5 0.0 1.6 1.8 0.2 0.1 0.2 0.6 0.5 4.6 2.5 0.2 0.7 0.5 0.7 0.3 1.7 0.8 15.6 7.2 0.2 0.4 0.9 4.6 0.3 0.0 4.4 1.6 2.9 0.0 8.2 0.2 2.6 0.0 427.6 2.2 0.0 1.7 1.1 0.6 0.0 0.3 2.1 0.0 1.0 0.5 0.4 0.5 1.4 18.8 31.3 0.0 0.0 0.9 9.8 0.9 4.8 1.2 0.1 0.8 0.0 0.2 36.2 0.2 3.2 0.9 0.0 0.4 0.3 0.0 2.5 0.1 0.7 0.4 0.6 0.2 1.4 18.6 15.6 2.9 9.1 0.5 5.6 0.3 20.2 0.7 0.3 0.9 0.3 0.4 14.8 0.4 0.1 0.1 1.3 3.9 0.1 0.3 0.7 4.9 0.6 0.7 0.1 0.6 0.4 1.6 0.1 0.2 0.3 0.5 0.2 0.1 0.1 0.2 0.4 0.2 2.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 74.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 9.3 4.9 4.9 0.0 0.4 0.9 0.1 0.0 0.0 TMEM218 ENSG00000150433 "Transmembrane protein 218" A2RU14 11 125096545-125111763 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038489 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA038489: AB_10672748" "unprognostic (3.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.60e-2)" "unprognostic (2.41e-3)" "unprognostic (8.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.63e-2)" "unprognostic (7.09e-3)" "unprognostic (2.18e-1)" "unprognostic (6.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.95e-2)" "prognostic favorable (5.50e-4)" "unprognostic (6.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.72e-2)" 17.7 18.1 4.8 9.5 5.5 5.3 14.0 5.3 6.5 15.5 5.3 13.5 8.4 16.6 6.9 11.6 14.8 7.4 10.2 4.6 5.4 12.7 12.9 12.0 10.5 6.0 5.5 15.0 14.5 10.3 15.2 5.9 5.8 13.0 6.0 6.5 10.9 6.8 9.2 8.9 11.8 8.3 5.7 16.6 13.2 5.6 5.1 8.4 10.9 5.7 7.0 13.8 13.2 6.3 12.5 24.0 14.9 18.2 13.5 18.6 9.0 12.2 9.2 9.3 12.0 2.5 35.9 15.6 29.9 7.5 14.2 14.2 9.4 11.6 12.2 22.0 13.5 35.1 6.1 10.0 13.3 11.1 12.6 14.7 15.2 16.5 19.6 14.9 13.7 19.1 14.4 19.4 16.2 6.4 2.9 23.3 12.2 34.0 22.6 16.3 18.0 12.0 8.3 12.3 12.9 19.4 16.6 6.6 9.1 8.7 31.3 15.7 17.6 11.4 10.3 13.4 13.5 11.1 10.1 12.9 9.1 22.9 20.3 43.7 40.1 17.4 21.6 31.6 18.7 29.6 20.5 20.5 47.4 23.9 17.2 20.4 15.7 32.5 30.9 41.1 20.5 27.0 4.8 5.5 5.3 6.5 4.6 5.4 6.0 5.5 5.8 5.7 5.1 6.3 21.0 19.2 13.4 7.8 17.8 12.1 19.6 34.6 19.4 7.0 22.1 24.6 8.1 15.7 16.6 14.7 0.0 28.0 18.1 5.7 27.4 20.5 3.4 23.1 22.4 15.8 10.8 14.5 4.4 16.2 18.4 21.1 8.6 10.6 3.8 22.2 18.5 15.1 42.2 23.5 7.4 11.7 20.3 21.0 17.5 1.9 10.2 21.9 17.8 14.0 26.0 26.0 18.6 9.5 11.2 13.1 3.9 16.6 15.8 9.4 8.5 19.7 29.4 12.4 26.3 16.7 18.3 16.6 13.8 18.0 14.2 9.7 14.5 27.0 13.7 16.6 TMEM248 "C7orf42, FLJ10099, FLJ13090" ENSG00000106609 "Transmembrane protein 248" Q9NWD8 7 66921225-66958551 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016495 Uncertain Approved Vesicles NA NA 1600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA016495: AB_1848643" "unprognostic (6.74e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (4.64e-2)" "unprognostic (6.67e-3)" "unprognostic (9.36e-2)" "unprognostic (1.39e-2)" "unprognostic (4.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.54e-2)" "unprognostic (9.18e-2)" "unprognostic (2.80e-3)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.11e-2)" "unprognostic (8.28e-2)" "unprognostic (5.57e-2)" 31.8 39.7 29.2 27.5 30.8 17.8 34.8 25.3 29.0 46.6 57.5 40.8 42.4 44.3 40.6 26.6 45.0 38.6 32.4 32.2 36.1 36.3 49.4 38.7 36.5 27.3 31.0 50.0 40.3 50.0 31.7 34.5 31.0 43.1 41.1 39.0 39.6 40.9 23.1 29.5 37.4 39.2 26.3 34.2 43.6 32.6 40.1 29.5 46.1 21.4 35.0 34.0 32.4 28.0 46.4 53.3 44.2 63.4 98.2 75.0 38.7 55.7 95.1 51.8 55.9 38.9 59.2 46.7 66.3 75.5 70.8 40.8 38.3 45.9 64.0 43.1 28.2 34.2 36.9 45.4 63.5 57.6 45.5 68.0 52.4 43.6 36.1 75.4 68.5 36.1 66.6 30.6 83.4 28.1 54.3 70.5 65.9 47.5 36.1 39.3 51.4 79.3 70.3 35.1 30.7 65.6 49.1 89.0 50.6 65.6 44.8 52.1 63.9 72.4 35.4 48.0 61.9 37.2 45.4 52.1 60.6 62.9 70.5 2.3 4.0 7.7 6.0 4.3 7.2 8.3 6.5 6.4 3.2 8.1 6.3 6.8 5.8 7.3 2.7 8.3 4.7 1.9 29.2 30.8 25.3 29.0 32.2 36.1 27.3 31.0 31.0 26.3 40.1 28.0 55.1 51.3 42.7 14.7 66.2 64.5 53.5 23.6 46.7 18.5 60.6 44.2 25.0 51.5 25.2 53.3 6.2 48.3 75.2 100.8 11.7 37.0 106.2 37.8 34.5 51.7 27.6 45.9 25.8 47.2 81.2 60.9 55.5 35.0 28.5 44.8 58.2 109.9 52.7 18.5 26.4 82.6 16.2 65.7 76.5 172.3 63.6 53.0 49.8 20.6 46.2 96.7 62.8 24.1 27.7 60.2 62.3 65.8 76.5 108.8 64.4 34.3 36.9 12.7 32.9 40.3 47.7 111.5 57.9 42.2 73.9 88.1 64.4 46.4 60.3 98.7 TMEM251 "C14orf109, DKFZP564F1123" ENSG00000153485 "Transmembrane protein 251" Q8N6I4 14 93184951-93188463 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 113.5;Hofbauer cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048559 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Golgi apparatus" "HPA048559: AB_2680441" "unprognostic (1.21e-2)" "unprognostic (4.56e-2)" "unprognostic (4.61e-3)" "unprognostic (3.37e-2)" "unprognostic (2.14e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (6.14e-7)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (9.99e-3)" "unprognostic (5.80e-3)" "unprognostic (1.58e-1)" "prognostic favorable (1.10e-4)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (7.47e-2)" "unprognostic (6.17e-2)" 16.6 22.9 7.3 6.4 7.8 2.7 16.9 7.9 10.0 15.5 8.2 22.9 10.3 14.2 16.5 13.1 14.7 6.7 25.6 7.6 7.6 33.2 17.2 17.1 8.0 7.7 7.8 14.2 21.2 10.3 19.8 6.9 7.8 25.7 12.5 20.7 19.6 9.2 30.6 13.7 18.1 6.8 7.4 15.9 21.8 8.4 8.1 8.6 17.6 12.4 6.9 17.2 12.8 9.0 11.0 12.1 15.3 16.1 17.2 7.3 9.4 7.9 8.2 12.7 16.2 7.8 11.1 12.1 12.9 7.9 15.9 15.9 17.8 12.6 17.7 9.3 13.4 10.9 8.8 18.3 15.2 16.0 14.7 9.3 14.6 10.0 16.2 6.8 12.2 13.5 9.3 12.0 11.6 52.5 10.2 12.8 8.3 28.0 11.6 4.7 16.0 11.3 16.6 23.6 12.9 13.4 11.7 6.0 36.9 12.4 17.7 11.4 5.0 6.1 10.8 14.6 9.4 9.3 16.0 11.8 11.4 6.1 9.1 6.8 9.7 13.6 3.9 9.4 2.9 4.7 4.6 4.4 8.0 5.5 5.2 5.9 10.5 5.3 13.0 7.3 4.1 4.2 7.3 7.8 7.9 10.0 7.6 7.6 7.7 7.8 7.8 7.4 8.1 9.0 13.4 3.2 14.4 5.2 22.4 23.2 37.9 33.6 13.1 14.8 41.1 39.1 22.5 32.9 22.0 31.3 27.1 36.6 16.5 44.8 113.5 30.3 1.8 33.1 16.3 11.9 15.0 11.3 5.9 26.6 21.1 16.6 20.9 35.7 17.2 15.2 8.9 19.2 110.1 13.5 7.8 36.1 26.4 28.4 20.0 2.3 11.8 39.6 32.0 2.8 16.2 34.8 12.3 5.0 13.8 17.7 23.8 10.9 13.1 43.3 31.7 69.6 17.2 30.6 39.5 13.9 23.2 4.5 17.8 18.1 31.1 27.4 16.1 17.6 30.9 36.4 TMEM273 "C10orf128, Em:AC084727.5" ENSG00000204161 "Transmembrane protein 273" Q5T292 10 49154725-49188585 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 37.8;dendritic cells: 10.1;Hofbauer cells: 82.9;Macrophages: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 269.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 269.0" "Cell line enhanced" "Detected in some" "HDLM-2: 214.8;HEL: 51.7;K-562: 101.4;U-266/84: 38.3;U-87 MG: 102.2;U-937: 91.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058166 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA058166: AB_2683627" "unprognostic (1.33e-1)" "unprognostic (5.67e-4)" "unprognostic (1.34e-2)" "unprognostic (1.21e-1)" "unprognostic (4.50e-2)" "unprognostic (4.13e-2)" "unprognostic (5.86e-3)" "unprognostic (9.13e-3)" "unprognostic (2.61e-1)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (2.86e-5)" "unprognostic (2.45e-2)" "unprognostic (2.22e-2)" "unprognostic (8.69e-3)" "unprognostic (1.24e-1)" 31.5 3.0 15.1 17.2 22.1 4.0 27.5 23.0 27.1 15.1 13.4 12.8 8.8 13.7 6.1 8.4 12.8 18.3 28.0 15.2 18.2 6.0 9.5 27.1 22.2 25.0 22.8 3.9 4.0 14.4 3.3 10.9 25.0 8.2 14.2 1.1 9.8 7.8 8.5 7.3 24.3 20.9 18.9 29.8 8.9 1.9 20.5 7.8 10.2 16.5 23.4 14.4 12.7 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 214.8 0.0 51.7 0.0 0.0 0.0 0.5 21.9 0.0 0.0 0.0 0.0 0.0 1.4 0.2 101.4 6.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.3 0.0 0.0 0.0 0.1 0.0 38.3 0.1 102.2 91.6 0.0 24.9 4.2 269.0 22.9 1.4 36.5 35.9 13.8 22.0 19.8 18.5 0.7 6.1 19.4 0.2 0.7 0.6 11.2 11.5 15.1 22.1 23.0 27.1 15.2 18.2 25.0 22.8 25.0 18.9 20.5 30.7 37.8 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 1.8 0.0 0.8 10.1 0.0 0.0 0.1 0.0 1.1 0.2 9.4 0.0 0.0 0.0 0.0 0.7 0.5 0.0 2.0 0.0 0.0 0.0 0.0 82.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.1 5.6 0.0 0.0 0.0 TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.6;Theca cells: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" 2.8 2.7 2.6 2.2 2.2 0.3 3.2 2.1 2.8 2.3 3.8 1.5 1.4 2.2 1.0 2.3 2.6 4.0 2.9 2.1 2.6 9.5 2.6 3.5 4.7 3.1 2.7 7.1 3.4 5.4 2.2 4.3 2.5 1.6 1.8 5.7 2.7 1.4 2.9 17.6 2.0 1.9 2.7 4.9 2.1 2.3 4.0 1.6 2.1 2.5 2.5 2.3 3.6 4.5 0.0 0.2 0.6 3.1 2.7 0.0 0.1 0.6 0.5 0.5 0.5 0.0 0.4 0.0 1.2 0.6 3.0 0.3 0.2 0.1 0.3 0.2 1.9 0.2 0.1 0.0 2.1 0.0 2.8 3.8 1.2 0.1 0.2 0.7 1.7 1.8 0.6 0.0 1.3 1.7 0.0 0.0 0.2 0.5 1.6 0.0 5.1 0.0 17.5 3.8 1.0 1.3 1.0 3.2 1.4 1.1 3.9 0.4 1.9 0.5 0.2 0.1 0.1 3.2 2.7 0.0 1.1 0.0 1.1 0.0 1.9 0.1 0.2 1.4 0.5 0.0 0.2 0.4 3.4 0.1 0.4 0.8 0.0 0.1 0.5 2.0 0.5 0.8 2.6 2.2 2.1 2.8 2.1 2.6 3.1 2.7 2.5 2.7 4.0 4.5 1.9 0.0 0.0 0.3 0.0 0.1 0.8 0.4 0.0 5.2 3.5 1.8 2.2 0.0 0.7 11.0 8.4 0.5 1.4 0.6 7.9 7.8 12.2 1.1 1.9 2.1 3.5 0.0 0.5 8.0 0.3 1.7 1.1 1.0 0.0 3.0 3.9 1.6 40.6 0.0 0.8 0.8 0.0 12.7 0.8 12.1 2.1 8.3 0.0 3.7 2.3 2.6 0.0 2.0 0.1 7.4 0.1 1.9 0.4 0.6 0.0 8.3 0.4 4.8 6.6 0.4 1.2 7.8 2.6 0.2 0.3 2.3 0.7 17.4 0.2 0.4 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TPP1 "CLN2, LPIC, SCAR7, TPP-1" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612768-6619448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 261.6;Kupffer cells: 376.5;Macrophages: 219.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" NA NA 9500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 74.7 145.9 71.0 74.6 81.0 111.7 44.3 80.3 81.4 53.8 120.1 59.1 59.9 74.0 43.1 39.5 47.1 65.1 56.3 70.6 78.4 71.6 92.7 81.5 77.7 85.2 82.6 49.7 36.2 54.2 63.6 94.2 81.0 38.9 59.7 48.5 42.5 57.5 31.4 39.5 73.3 92.0 74.7 135.0 48.4 20.0 83.3 47.4 45.7 39.0 60.9 68.4 42.8 90.4 26.1 48.1 25.9 50.5 309.9 160.1 21.8 50.9 220.7 36.9 62.0 20.1 122.5 37.4 32.6 136.6 220.2 85.8 48.3 68.7 57.9 37.3 27.6 32.2 23.8 54.9 210.9 45.8 182.6 231.8 104.5 45.9 102.6 240.4 158.8 32.9 59.8 124.6 110.4 30.2 16.6 52.4 18.0 61.5 57.1 36.1 21.6 77.0 62.8 38.2 4.5 20.4 52.6 44.6 91.0 76.5 30.8 79.7 188.0 119.7 33.1 101.1 19.8 92.3 95.3 14.0 139.8 101.7 64.5 67.0 167.1 38.2 39.9 171.2 30.0 35.1 31.4 41.0 185.9 37.0 20.1 27.2 27.5 29.1 125.1 93.1 60.3 138.8 71.0 81.0 80.3 81.4 70.6 78.4 85.2 82.6 81.0 74.7 83.3 90.4 32.0 25.6 37.3 31.6 53.0 23.7 28.4 29.8 13.1 24.8 21.1 23.9 41.8 50.1 26.8 16.5 12.5 35.4 71.0 55.2 5.9 42.2 11.8 13.3 30.2 40.7 16.7 37.5 12.5 13.4 45.3 40.3 16.3 24.8 62.2 25.6 75.7 81.0 261.6 15.2 12.4 31.3 26.4 376.5 126.5 11.2 27.1 219.8 90.7 15.9 156.0 37.9 49.4 8.0 21.9 17.4 44.1 26.4 26.4 23.5 99.7 51.6 14.5 23.8 6.6 19.0 20.3 0.8 1.1 27.6 20.0 88.0 42.2 24.6 32.5 26.5 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TRIM14 KIAA0129 ENSG00000106785 "Tripartite motif containing 14" Q14142 9 98069275-98119222 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 75.0;Kupffer cells: 80.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053217 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" "HPA053217: AB_2682082" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.92e-1)" "unprognostic (4.39e-2)" "unprognostic (1.77e-1)" "unprognostic (9.80e-2)" "unprognostic (9.00e-2)" "unprognostic (8.14e-2)" "unprognostic (2.69e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.55e-3)" "unprognostic (4.57e-2)" 6.4 5.3 9.0 18.4 7.6 12.1 10.0 4.7 7.7 5.8 4.7 18.9 29.5 4.3 1.8 19.5 6.3 9.6 1.6 7.7 7.3 11.4 22.3 14.9 25.6 14.1 8.1 2.9 3.1 13.5 5.1 5.0 8.4 9.4 16.8 2.7 10.6 5.6 1.0 9.9 30.4 8.8 9.4 26.8 11.6 7.8 9.7 32.7 2.9 1.0 21.8 12.7 9.1 8.9 25.5 12.9 0.6 11.3 0.0 3.9 8.3 14.8 28.1 79.3 67.8 24.8 14.9 33.5 11.8 16.1 47.2 28.6 24.9 16.5 24.1 43.3 20.0 9.9 20.3 24.6 17.1 53.1 10.7 2.4 8.0 11.6 14.8 10.6 10.1 37.4 39.6 15.5 7.3 32.6 42.2 16.7 14.2 56.3 39.5 27.4 1.4 17.2 6.3 15.6 4.0 3.3 20.8 43.2 14.3 2.8 11.4 30.4 7.1 3.3 8.5 1.2 20.5 6.7 8.3 11.1 9.1 41.1 11.4 1.0 14.4 2.1 15.1 28.4 16.1 8.3 17.1 15.7 15.8 5.6 13.1 11.4 4.0 13.0 59.0 15.3 23.1 17.2 9.0 7.6 4.7 7.7 7.7 7.3 14.1 8.1 8.4 9.4 9.7 8.9 2.1 3.2 8.8 3.3 15.3 2.8 14.3 11.8 15.4 35.1 8.7 8.3 1.0 7.2 14.2 5.5 75.0 5.0 28.8 40.0 3.9 4.9 8.8 4.8 8.9 4.1 12.6 5.9 7.0 13.6 16.9 3.2 13.3 5.4 1.3 12.0 7.5 22.4 15.4 3.3 5.4 15.3 10.2 80.6 2.4 9.9 0.3 32.6 1.8 2.8 16.5 1.9 30.9 12.1 0.9 15.0 13.5 1.5 8.5 19.1 38.1 21.1 17.0 4.4 0.0 1.4 2.0 16.3 3.8 17.3 3.3 3.3 21.3 5.8 19.4 21.1 TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 50.0;Hofbauer cells: 50.6;monocytes: 39.4;NK-cells: 49.4" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 78.8;fHDF/TERT166: 108.4;HMC-1: 89.0;SK-MEL-30: 94.7;TIME: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" 17.1 20.5 6.2 18.3 8.0 22.8 10.4 5.7 7.6 7.9 3.9 7.0 6.6 7.6 1.8 5.3 7.3 8.5 11.2 6.1 9.8 4.7 4.0 30.2 24.6 10.6 15.4 7.8 6.3 8.9 1.6 20.1 17.2 6.0 6.2 1.0 4.5 2.6 3.9 6.5 10.7 11.8 7.1 23.7 5.9 2.0 7.3 15.7 6.2 5.5 16.2 10.7 7.2 8.0 0.3 1.6 0.0 0.0 25.6 78.8 4.9 8.3 9.4 9.1 8.9 0.3 0.3 9.6 2.2 108.4 7.8 0.2 0.2 0.0 5.1 43.0 0.7 10.7 0.0 26.1 30.0 14.8 89.0 35.2 0.0 54.0 0.7 4.1 3.8 12.9 37.2 26.0 43.4 0.5 19.1 20.5 0.1 0.1 0.2 11.3 0.3 4.3 40.6 1.1 1.2 0.1 0.0 0.0 94.7 41.0 0.0 12.7 84.9 0.2 0.3 0.3 1.1 0.1 0.3 5.1 8.2 21.6 12.6 60.8 26.6 35.8 63.4 52.8 55.5 19.2 46.0 59.3 58.7 20.3 25.7 44.8 6.8 63.2 49.4 51.3 49.9 43.1 6.2 8.0 5.7 7.6 6.1 9.8 10.6 15.4 17.2 7.1 7.3 8.0 15.8 0.0 5.3 1.0 11.1 2.8 0.1 0.0 0.0 0.6 0.5 0.4 1.1 1.5 0.6 0.0 0.0 2.2 29.3 0.0 0.0 0.2 0.3 0.4 0.1 12.3 0.0 6.7 3.3 3.6 2.3 11.0 1.1 0.1 50.0 16.7 8.9 0.4 50.6 0.0 2.6 0.0 0.0 19.5 18.2 0.0 1.8 28.7 28.4 4.7 39.4 0.3 49.4 0.5 0.5 4.7 0.1 4.5 15.1 0.0 0.0 0.1 0.8 0.6 26.3 7.9 23.6 1.3 5.9 0.4 1.7 16.1 26.8 2.8 0.0 0.1 TTYH3 KIAA1691 ENSG00000136295 "Tweety family member 3" Q9C0H2 7 2631986-2664802 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 135.0;Kupffer cells: 85.0;Melanocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 10.0;non-classical monocyte: 8.4" "Lineage enriched" "Detected in many" 4 "monocytes: 10.0" "Cell line enhanced" "Detected in all" "U-2 OS: 205.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053520 Uncertain NA NA 55000 "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" "HPA053520: AB_2682176" "unprognostic (2.53e-2)" "unprognostic (6.65e-3)" "unprognostic (3.86e-3)" "unprognostic (1.35e-1)" "unprognostic (5.25e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (2.53e-5)" "unprognostic (5.53e-2)" "unprognostic (1.96e-1)" "unprognostic (8.59e-3)" "unprognostic (5.40e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (2.58e-5)" "unprognostic (7.90e-2)" "unprognostic (5.45e-2)" "unprognostic (1.03e-1)" "unprognostic (8.85e-2)" 25.6 29.4 31.6 30.7 32.7 11.8 16.3 43.3 39.3 19.0 1.8 15.8 19.9 18.7 1.9 7.7 16.7 18.3 12.4 24.1 8.9 43.3 37.4 25.6 19.4 11.4 18.4 15.0 9.6 4.6 14.2 23.8 9.0 20.9 6.7 5.3 25.4 7.3 3.9 12.0 27.7 10.6 4.7 40.8 13.3 14.4 33.8 11.7 21.6 1.7 7.3 14.6 11.4 10.7 43.8 84.9 88.0 123.7 24.2 21.7 98.5 69.4 61.8 29.8 34.9 35.3 30.9 3.6 82.4 66.1 78.8 19.3 12.7 31.5 8.4 5.9 42.9 21.8 17.9 98.7 32.3 4.5 13.2 52.0 15.1 32.0 8.3 55.5 99.4 21.6 6.7 4.7 20.1 25.5 16.1 47.0 112.7 61.7 32.9 66.3 63.7 4.1 47.0 47.0 36.8 185.1 42.8 8.2 40.3 58.1 22.3 117.5 117.9 69.3 205.4 40.9 78.6 8.0 5.3 12.1 50.0 16.1 152.7 0.0 4.9 1.5 0.2 10.0 0.2 0.3 0.1 0.1 2.2 0.3 0.3 0.0 0.5 0.3 8.4 1.0 0.2 3.4 31.6 32.7 43.3 39.3 24.1 8.9 11.4 18.4 9.0 4.7 33.8 10.7 8.6 0.0 4.2 38.5 4.8 6.5 1.8 12.9 2.2 9.0 10.2 7.1 2.7 18.6 8.8 9.2 4.2 1.8 2.9 9.6 3.9 20.3 0.5 2.8 12.8 21.0 7.8 1.7 22.4 5.2 28.8 9.0 7.1 6.0 2.5 19.4 15.4 21.1 135.0 30.3 25.4 20.5 8.2 85.0 32.6 5.2 8.1 52.4 56.9 17.8 30.7 4.0 2.1 8.5 6.1 20.2 2.7 3.8 1.5 5.0 28.3 32.2 3.8 2.2 6.6 2.2 8.0 1.7 2.3 1.2 3.7 2.5 3.8 4.9 11.2 3.1 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 UNC93B1 UNC93 ENSG00000110057 "Unc-93 homolog B1, TLR signaling regulator" Q9H1C4 11 67991100-68004982 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 76.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 96.2;Kupffer cells: 78.3;Macrophages: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "CAPAN-2: 128.9;RPMI-8226: 368.2;SK-BR-3: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038716, HPA038717, HPA042803" Approved Approved Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA038716: AB_2676169, HPA038717: AB_10674836, HPA042803: AB_2678176" "unprognostic (3.32e-2)" "unprognostic (1.75e-1)" "unprognostic (3.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (7.66e-2)" "unprognostic (1.29e-2)" "unprognostic (9.36e-2)" "unprognostic (5.82e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (4.76e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.73e-2)" "unprognostic (1.85e-2)" "unprognostic (7.05e-3)" "unprognostic (5.23e-3)" 18.7 17.7 4.9 19.9 5.6 19.9 15.4 5.0 7.5 19.0 6.4 20.2 22.5 7.7 0.8 20.5 15.7 9.8 7.3 4.9 5.0 16.4 15.3 29.5 29.5 10.7 6.5 6.2 17.1 2.6 6.7 6.4 8.1 16.4 3.1 0.1 27.9 8.8 3.5 16.3 35.8 3.1 7.9 76.7 20.6 1.7 6.8 3.5 14.8 1.5 7.3 20.6 15.0 10.2 18.9 34.1 2.5 13.8 7.2 2.7 28.2 8.3 7.7 13.0 11.8 2.8 128.9 40.9 30.8 4.0 11.0 44.9 1.0 7.0 0.4 14.1 9.3 4.2 11.1 6.4 11.2 30.0 22.7 6.0 7.6 3.8 1.5 5.0 2.6 6.4 3.0 19.3 2.0 18.7 0.2 23.9 6.2 46.8 16.7 24.5 0.0 368.2 11.8 10.7 3.9 5.5 14.0 95.6 19.3 1.0 35.4 39.0 9.2 8.6 12.2 12.8 0.8 13.2 18.8 7.0 16.0 30.7 10.5 0.1 3.8 6.6 0.1 7.2 0.2 2.5 0.2 0.2 5.1 2.7 0.0 0.0 3.2 2.1 7.7 14.8 0.0 1.2 4.9 5.6 5.0 7.5 4.9 5.0 10.7 6.5 8.1 7.9 6.8 10.2 12.5 9.6 9.1 4.6 45.3 4.0 21.9 12.5 9.1 0.0 16.4 13.1 1.8 40.0 21.0 16.5 0.0 10.3 63.3 23.2 1.9 36.8 0.8 32.0 5.9 10.0 4.2 3.0 1.1 23.4 47.8 8.0 20.9 17.2 7.0 9.3 10.0 5.4 96.2 5.0 0.1 17.2 14.2 78.3 28.4 0.1 4.4 85.3 23.2 13.1 57.5 4.7 8.2 0.0 0.7 49.7 25.6 4.1 33.8 27.0 31.7 6.9 57.3 0.5 0.0 8.3 9.8 0.2 1.1 12.9 6.5 7.3 10.5 2.1 23.1 37.7 USF2 "bHLHb12, FIP" ENSG00000105698 "Upstream transcription factor 2, c-fos interacting" Q15853 19 35268962-35279821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029764, HPA046567" Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Vesicles "HPA029764: AB_2673190, HPA046567: AB_2679702" "unprognostic (6.10e-3)" "unprognostic (2.27e-1)" "unprognostic (1.06e-2)" "unprognostic (5.03e-3)" "unprognostic (4.60e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "unprognostic (2.87e-1)" "unprognostic (2.10e-1)" "unprognostic (7.07e-2)" "prognostic favorable (5.12e-5)" "unprognostic (7.75e-2)" "unprognostic (8.12e-2)" "unprognostic (7.47e-2)" "unprognostic (5.75e-2)" "unprognostic (6.90e-2)" "prognostic favorable (3.28e-4)" 126.7 132.5 188.9 130.4 191.7 177.7 105.4 190.2 192.9 109.3 147.9 120.8 105.3 104.4 51.5 104.6 104.1 66.3 196.6 181.0 180.3 97.8 185.2 102.2 154.9 192.9 185.4 164.5 121.1 109.4 149.1 63.5 187.2 99.8 54.1 90.4 97.9 57.2 359.3 122.0 112.7 52.4 186.4 160.5 104.1 51.7 191.7 101.3 125.8 195.1 96.7 100.2 99.9 183.2 189.2 190.2 93.6 91.1 161.7 81.5 89.2 101.0 119.7 90.4 69.3 87.3 95.5 183.7 157.6 86.3 96.4 56.5 88.6 79.6 45.4 306.4 135.8 107.5 111.1 143.1 97.8 182.5 177.5 71.7 108.3 58.6 89.1 151.3 62.2 119.6 135.3 260.0 70.5 218.8 200.7 69.8 78.7 171.3 61.1 190.9 123.2 171.2 74.8 119.5 159.3 120.7 188.2 200.4 346.7 80.7 81.8 142.4 107.4 150.0 101.0 99.5 134.4 260.0 286.6 199.7 139.4 114.8 201.0 44.5 8.3 11.1 6.8 11.2 8.2 10.2 7.0 9.0 13.4 13.5 6.3 6.0 7.8 11.7 6.9 50.6 13.8 7.7 188.9 191.7 190.2 192.9 181.0 180.3 192.9 185.4 187.2 186.4 191.7 183.2 58.2 6.4 22.4 29.7 72.5 23.7 23.7 18.7 20.5 66.0 42.2 38.4 71.6 35.8 15.5 31.3 33.3 24.2 108.1 50.7 56.7 33.5 1.1 25.6 31.3 36.5 52.1 37.2 19.7 57.8 38.5 32.7 30.5 34.0 20.3 45.7 38.6 50.5 107.0 94.2 16.9 33.6 20.3 66.8 42.9 3.4 32.0 91.9 26.6 28.1 37.8 118.9 35.0 12.1 19.5 36.0 37.1 31.2 63.8 23.1 58.1 51.7 11.0 53.9 13.1 40.9 35.8 9.0 10.6 34.3 24.7 17.5 56.2 52.0 33.0 35.6 VMA21 "MEAX, XMEA" ENSG00000160131 "Vacuolar ATPase assembly factor VMA21" Q3ZAQ7 X 151396515-151409364 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010972 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010972: AB_1853034" "unprognostic (1.17e-1)" "prognostic favorable (2.30e-5)" "unprognostic (6.75e-2)" "unprognostic (9.78e-3)" "unprognostic (6.48e-2)" "unprognostic (4.68e-2)" "unprognostic (1.88e-3)" "unprognostic (4.36e-2)" "unprognostic (5.16e-2)" "unprognostic (1.74e-2)" "unprognostic (2.55e-1)" "unprognostic (8.30e-2)" "unprognostic (7.88e-2)" "unprognostic (4.17e-2)" "unprognostic (3.21e-2)" "unprognostic (3.90e-2)" "unprognostic (2.76e-1)" 10.4 12.2 16.5 7.6 17.0 22.8 10.6 16.2 17.1 9.6 18.3 6.8 6.3 9.0 14.1 9.3 13.6 6.6 7.5 18.5 23.5 12.8 9.8 8.0 11.4 19.8 20.8 10.5 8.7 11.6 10.9 12.0 20.3 8.6 6.6 15.6 8.1 8.2 7.9 12.5 6.6 7.8 20.1 9.9 7.0 8.3 18.3 10.3 13.3 7.1 12.4 8.5 7.6 19.6 21.5 23.5 26.7 28.3 25.9 24.7 26.2 23.7 25.4 21.4 21.1 17.8 27.5 63.1 75.3 24.2 24.0 19.1 37.5 22.6 33.2 22.2 18.6 27.5 25.9 32.3 34.6 52.4 30.4 25.8 27.4 24.3 34.1 22.8 24.9 27.2 14.9 32.2 40.6 20.4 35.8 51.9 33.3 25.7 24.5 35.9 31.8 40.6 25.5 17.3 9.6 20.3 18.4 24.3 29.0 24.4 14.9 34.1 25.4 34.6 15.6 44.3 38.5 27.1 50.8 91.7 35.2 63.9 35.4 11.9 12.4 7.7 6.5 14.4 8.5 7.7 8.5 8.3 13.6 6.0 11.3 10.5 2.8 12.8 13.1 12.2 9.4 10.6 16.5 17.0 16.2 17.1 18.5 23.5 19.8 20.8 20.3 20.1 18.3 19.6 38.5 22.4 24.4 9.1 46.5 44.9 28.0 35.3 42.7 40.2 35.8 31.1 46.8 30.0 21.0 31.3 18.8 33.2 62.9 21.0 19.6 28.2 50.6 44.1 22.4 34.6 22.1 52.5 16.4 33.0 66.7 28.0 15.8 24.1 24.1 25.7 32.2 38.9 143.7 20.2 19.1 22.5 20.3 150.3 86.6 51.5 18.3 89.8 39.2 5.6 142.9 49.9 53.5 13.0 14.3 47.7 17.6 22.6 50.9 43.8 26.8 33.5 28.6 26.2 52.6 31.7 34.5 27.4 58.8 46.0 51.6 31.9 41.6 37.0 21.8 30.5 VPS11 "PEP5, RNF108" ENSG00000160695 "VPS11 core subunit of CORVET and HOPS complexes" Q9H270 11 119067818-119081972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039020 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA039020: AB_10674847" "unprognostic (6.97e-2)" "unprognostic (3.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-2)" "unprognostic (1.43e-2)" "unprognostic (1.28e-1)" "unprognostic (2.59e-3)" "unprognostic (1.11e-1)" "unprognostic (3.21e-1)" "unprognostic (9.17e-2)" "unprognostic (6.01e-2)" "unprognostic (1.56e-1)" "prognostic favorable (1.44e-4)" "unprognostic (4.07e-2)" "unprognostic (4.05e-2)" "unprognostic (2.71e-2)" "unprognostic (2.25e-1)" 21.6 25.1 16.7 14.7 16.8 17.6 19.4 16.7 18.6 20.8 15.3 19.6 13.4 23.5 19.0 14.6 20.1 12.8 16.6 17.6 17.8 16.9 11.5 16.8 18.1 17.0 17.6 22.5 18.0 22.4 22.8 17.3 17.3 18.4 13.4 17.6 18.2 16.5 21.7 21.4 17.9 19.5 16.0 21.7 18.5 13.3 17.5 20.1 21.1 21.1 17.2 21.0 17.4 18.4 11.6 11.8 12.8 9.8 27.5 24.2 14.0 15.4 18.4 15.3 16.5 19.9 24.2 16.6 21.5 30.2 27.1 21.0 16.1 20.7 15.1 17.1 8.0 36.6 12.0 19.5 30.8 22.9 21.5 29.6 21.3 23.2 15.9 27.2 24.4 13.9 29.5 28.8 20.2 30.5 19.3 21.6 6.4 21.2 22.5 21.7 21.1 12.6 18.2 24.1 10.2 17.5 19.2 25.3 16.8 13.7 38.3 20.1 24.5 19.1 7.1 6.9 11.5 11.3 11.0 15.6 14.0 27.2 17.0 24.8 16.8 12.8 16.4 13.9 16.8 11.3 13.7 15.2 20.7 11.9 12.9 16.6 3.8 16.5 19.0 8.7 16.5 13.9 16.7 16.8 16.7 18.6 17.6 17.8 17.0 17.6 17.3 16.0 17.5 18.4 9.9 6.4 10.5 8.1 10.2 2.9 4.4 7.0 8.6 10.2 8.1 9.8 7.6 8.6 12.1 9.2 12.5 11.2 16.2 9.7 9.8 8.2 7.8 9.9 10.0 10.7 9.6 6.3 9.6 10.1 7.0 9.7 11.2 9.9 15.2 10.2 13.2 6.0 17.0 5.0 9.9 10.1 6.1 14.8 8.9 3.0 17.1 12.6 7.2 7.5 11.6 9.2 5.2 6.6 14.4 7.2 6.8 15.4 11.5 3.6 9.2 11.0 10.5 15.5 13.1 6.2 10.2 11.3 7.3 6.5 4.8 14.1 12.2 9.4 9.5 3.8 VPS18 "KIAA1475, PEP3" ENSG00000104142 "VPS18 core subunit of CORVET and HOPS complexes" Q9P253 15 40894450-40903975 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040701 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "HPA040701: AB_10794145" "unprognostic (1.81e-1)" "unprognostic (4.53e-1)" "unprognostic (9.69e-3)" "unprognostic (1.55e-2)" "unprognostic (1.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.62e-3)" "unprognostic (1.60e-1)" "unprognostic (9.69e-3)" "unprognostic (2.12e-2)" "prognostic favorable (8.69e-4)" "unprognostic (1.39e-1)" "prognostic favorable (1.61e-6)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (6.73e-2)" "unprognostic (1.06e-2)" 8.6 11.8 9.2 7.3 9.9 21.3 7.4 12.0 10.3 7.5 8.0 9.7 6.8 11.3 8.7 9.2 8.3 7.7 12.9 9.2 10.8 9.8 10.7 9.0 8.8 11.5 10.3 7.5 5.9 11.2 9.6 6.2 12.9 8.7 4.1 3.8 8.3 8.3 13.0 9.5 9.0 8.2 9.1 11.9 9.6 6.2 11.3 7.5 7.9 9.5 7.2 9.8 6.1 12.1 9.9 23.1 11.1 19.1 35.5 15.1 15.2 20.3 29.4 24.5 29.9 29.5 5.9 5.3 19.0 24.3 31.1 25.7 23.4 23.0 10.3 12.2 15.8 23.5 22.2 17.0 31.3 19.8 30.2 26.2 11.9 24.6 13.6 11.5 26.0 11.8 16.5 13.1 20.9 13.0 13.4 21.8 14.7 10.1 15.7 27.1 12.6 9.9 20.0 52.3 12.8 12.8 14.6 28.4 13.7 13.5 17.7 22.0 25.8 24.8 12.9 25.0 13.4 13.0 20.9 14.4 27.2 21.5 12.5 7.3 10.9 13.1 10.1 7.4 8.3 8.3 5.2 7.8 11.1 5.8 5.4 5.8 12.0 7.8 10.6 4.8 9.8 9.0 9.2 9.9 12.0 10.3 9.2 10.8 11.5 10.3 12.9 9.1 11.3 12.1 3.3 3.2 7.2 2.0 7.5 2.4 2.3 7.7 4.0 9.0 4.2 2.3 6.7 5.7 10.4 7.3 6.2 7.1 11.0 12.0 3.9 16.7 1.1 6.8 3.7 6.9 11.9 1.3 4.0 7.7 4.6 5.0 12.2 8.2 7.0 8.1 7.5 10.8 21.4 6.7 4.1 6.4 10.2 10.9 6.6 1.8 7.2 9.5 8.8 2.8 13.2 6.8 12.3 1.5 3.1 11.5 5.9 9.8 4.0 3.2 10.3 11.4 5.4 7.1 6.6 4.1 4.5 5.8 6.2 8.0 2.0 10.8 6.9 7.5 5.8 5.8 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Vesicles, Cytosol" "HPA023044: AB_1858822, HPA063703: " "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.63e-2)" "unprognostic (4.90e-3)" "unprognostic (6.10e-2)" "unprognostic (7.75e-3)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.06e-2)" "unprognostic (1.60e-2)" "prognostic favorable (3.30e-4)" "unprognostic (3.26e-1)" "unprognostic (8.72e-2)" "unprognostic (2.25e-1)" "unprognostic (8.43e-2)" "unprognostic (7.99e-2)" "unprognostic (3.90e-2)" 17.7 16.2 4.5 4.6 5.4 4.9 16.9 4.6 6.3 18.2 6.6 11.5 4.8 18.9 2.4 9.9 17.4 1.6 10.9 4.3 4.4 11.9 32.8 13.7 5.6 5.9 5.1 21.4 11.0 2.4 13.1 3.9 5.3 16.0 1.7 0.8 11.0 5.9 18.2 18.4 17.8 5.1 4.7 24.3 11.0 7.5 6.1 6.6 10.5 2.1 4.2 15.4 13.7 6.4 0.7 12.3 1.7 9.1 12.4 7.0 9.2 0.9 0.2 0.6 0.0 1.8 4.4 4.9 6.5 5.4 6.2 12.2 6.3 8.4 0.4 9.5 12.8 0.3 8.8 5.9 22.1 4.1 7.6 17.8 8.8 5.9 4.1 1.9 5.0 3.7 1.0 6.3 7.6 6.8 1.3 7.6 3.9 4.2 9.4 6.4 2.9 6.8 3.7 2.0 2.2 5.0 4.3 3.4 15.4 0.1 6.0 6.1 6.8 4.8 5.4 7.9 6.7 0.5 1.3 3.1 7.7 5.9 2.4 0.0 1.4 2.8 1.1 2.3 1.3 1.3 1.2 1.2 1.8 1.0 0.8 1.1 0.3 2.1 2.3 3.3 1.2 1.1 4.5 5.4 4.6 6.3 4.3 4.4 5.9 5.1 5.3 4.7 6.1 6.4 6.3 12.8 10.3 6.5 4.2 2.5 2.9 4.4 8.6 4.5 4.8 5.3 3.6 4.3 3.8 0.0 4.2 2.5 9.9 6.8 1.9 3.1 0.7 2.1 6.2 5.4 1.2 14.3 5.3 4.5 1.9 8.2 6.6 2.9 4.5 6.2 4.6 27.7 23.8 5.0 5.3 4.6 10.2 22.3 4.5 1.2 16.4 15.3 0.0 9.4 7.5 2.5 9.2 5.0 7.6 4.8 4.8 15.1 5.3 2.9 8.7 20.1 6.4 1.8 19.7 5.9 4.5 0.7 2.0 3.4 1.7 2.3 4.7 5.8 4.4 1.7 ZDHHC24 ENSG00000174165 "Zinc finger DHHC-type containing 24" Q6UX98 11 66520637-66546235 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016619 Approved Approved Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "HPA016619: AB_2288672" "unprognostic (2.77e-1)" "unprognostic (2.51e-1)" "unprognostic (2.52e-1)" "unprognostic (1.55e-3)" "prognostic unfavorable (3.28e-4)" "unprognostic (8.76e-2)" "unprognostic (7.74e-3)" "unprognostic (7.11e-2)" "unprognostic (6.20e-2)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (1.48e-1)" "unprognostic (8.10e-2)" "unprognostic (6.99e-3)" "unprognostic (3.10e-1)" "unprognostic (4.88e-1)" "unprognostic (1.35e-1)" 5.2 6.9 5.8 3.3 4.5 5.0 4.7 4.2 5.4 3.6 5.8 3.5 2.8 4.3 5.1 4.3 3.9 2.2 3.6 4.9 5.2 6.2 4.6 4.5 4.3 5.5 5.2 2.7 7.1 6.0 4.7 2.5 4.8 4.5 2.1 2.6 5.0 2.7 2.9 5.1 4.7 1.9 4.4 7.2 4.8 3.7 6.4 3.1 5.9 1.1 3.0 4.0 3.4 4.5 5.2 7.4 2.4 6.5 5.8 4.7 6.2 3.9 3.4 3.1 2.1 6.5 7.7 1.6 11.5 3.3 8.3 11.9 1.9 3.4 2.1 7.6 4.9 2.9 3.7 4.1 5.5 3.4 6.9 5.6 6.2 2.5 3.6 3.7 5.1 13.0 4.2 4.3 4.0 10.4 7.4 8.6 5.3 12.2 7.6 8.8 5.3 9.3 3.9 3.6 3.5 5.6 6.7 6.5 11.6 2.7 9.5 2.4 8.0 7.1 2.4 8.3 3.1 6.9 2.2 2.1 6.2 1.5 8.2 3.0 5.9 1.0 7.3 5.7 6.6 6.4 6.0 8.4 7.2 7.5 3.8 5.9 2.2 8.0 5.0 23.1 6.6 6.1 5.8 4.5 4.2 5.4 4.9 5.2 5.5 5.2 4.8 4.4 6.4 4.5 21.7 12.8 8.3 7.8 21.9 8.0 15.2 26.8 10.8 9.6 21.5 15.2 4.5 22.8 17.3 23.9 10.4 33.0 49.9 29.0 9.8 50.3 13.5 15.1 14.4 23.3 14.4 6.3 7.6 49.4 37.2 15.0 17.9 19.8 8.9 18.5 23.2 14.9 63.9 23.5 7.0 17.8 20.3 42.8 14.8 12.1 7.5 27.9 17.8 5.6 36.4 16.9 46.4 4.0 8.5 42.8 40.6 9.8 15.8 24.9 54.8 35.2 14.7 10.3 19.7 11.2 15.1 29.6 4.1 21.6 8.1 24.1 23.3 18.5 21.8 23.1