Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 70.7;Proximal tubular cells: 91.0;Urothelial cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 38.7;ASC TERT1: 31.3;RPTEC TERT1: 27.1;TIME: 29.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 22000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 41.5 14.3 6.2 6.1 6.0 4.1 31.3 5.0 8.0 29.6 8.0 30.9 4.5 28.1 3.3 30.6 29.2 4.4 77.0 6.2 5.3 51.3 4.3 26.0 6.8 7.8 5.8 7.8 6.2 1.2 16.7 9.1 5.6 35.1 1.7 0.3 36.1 21.3 19.4 20.8 18.2 6.9 6.0 16.2 26.6 6.2 7.1 1.6 25.1 6.3 5.1 38.1 38.2 6.0 1.2 13.6 0.0 0.0 38.7 31.3 20.1 5.5 5.8 1.2 2.1 4.3 2.2 13.6 9.4 9.7 6.7 1.3 12.9 6.5 0.2 0.0 2.7 0.3 21.1 0.5 11.5 0.0 0.9 18.6 1.8 5.5 0.9 1.8 4.7 0.0 0.1 0.0 5.1 19.0 0.0 0.0 1.6 0.9 3.3 0.0 3.0 1.4 27.1 23.4 0.2 0.0 16.9 0.3 0.0 2.4 10.6 1.6 29.3 0.0 2.6 24.3 7.3 2.8 13.1 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 6.2 6.0 5.0 8.0 6.2 5.3 7.8 5.8 5.6 6.0 7.1 6.0 47.1 0.0 0.5 0.3 1.6 9.2 28.9 70.7 0.0 0.1 4.2 1.5 15.8 1.5 41.2 18.4 0.0 48.7 0.4 0.2 13.7 23.1 0.7 11.1 10.3 43.7 0.0 10.7 0.1 1.1 35.3 43.8 2.6 17.4 1.3 0.2 30.7 0.2 5.3 0.0 0.1 0.0 14.2 1.0 11.8 4.4 46.3 4.0 7.2 7.5 30.0 0.8 0.0 0.5 0.0 3.6 0.0 30.1 0.1 40.1 0.0 91.0 12.1 0.6 39.5 7.6 29.3 0.6 0.6 1.2 8.8 9.4 1.5 19.9 0.1 74.7 ABCA10 EST698739 ENSG00000154263 "ATP binding cassette subfamily A member 10" Q8WWZ4 17 69147214-69244846 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "ovary: 18.3" "Cell type enhanced" "Detected in many" "Early spermatids: 231.0;Excitatory neurons: 91.9;Fibroblasts: 64.3;Inhibitory neurons: 112.4;Late spermatids: 93.1;Microglial cells: 187.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 1.3;HUVEC TERT2: 1.3;RT4: 1.3;U-2197: 2.1" HPA014535 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA014535: AB_1844426" "unprognostic (1.45e-4)" "unprognostic (3.17e-1)" "unprognostic (7.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.52e-2)" "unprognostic (1.17e-2)" "unprognostic (3.78e-2)" "unprognostic (1.40e-1)" "unprognostic (4.51e-3)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "unprognostic (4.91e-1)" "unprognostic (2.70e-4)" "unprognostic (5.23e-3)" "unprognostic (6.98e-2)" "unprognostic (4.37e-2)" "unprognostic (9.86e-3)" 8.7 1.7 2.2 0.0 3.1 0.0 10.4 4.8 6.6 4.1 2.4 2.8 1.1 3.2 2.6 2.7 12.7 3.5 7.2 2.9 2.3 1.8 4.5 3.0 0.6 4.0 2.3 18.3 2.7 0.4 2.6 0.2 4.7 2.2 4.0 3.4 5.6 0.6 6.4 4.6 3.0 1.9 1.6 1.1 2.4 3.5 3.8 0.8 5.5 2.3 0.7 3.2 4.2 3.8 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 1.3 0.2 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.1 4.8 6.6 2.9 2.3 4.0 2.3 4.7 1.6 3.8 3.8 4.3 0.0 3.2 2.6 0.3 1.0 0.5 1.1 1.2 6.7 1.8 2.3 3.9 1.5 0.2 0.0 25.0 0.0 1.2 6.9 0.0 0.6 231.0 2.1 0.7 1.9 4.9 0.0 91.9 0.2 0.0 64.3 2.0 3.3 0.0 6.9 0.4 1.8 0.1 0.0 112.4 3.7 0.0 0.0 3.3 93.1 51.0 1.0 1.8 187.4 1.6 1.9 4.1 26.2 13.5 0.4 0.4 11.7 0.7 0.3 5.6 0.5 3.1 9.0 0.0 6.1 4.5 8.1 2.6 1.1 0.4 0.0 0.6 18.9 0.7 0.5 ABCA6 EST155051 ENSG00000154262 "ATP binding cassette subfamily A member 6" Q8N139 17 69078702-69141895 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 77.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Fibroblasts: 117.6;Hepatocytes: 110.3;Inhibitory neurons: 77.8;Leydig cells: 51.3;Microglial cells: 93.7;Theca cells: 45.4" "Cancer enriched" "Detected in some" 7 "liver cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 39.9;ASC TERT1: 56.0;HSkMC: 25.3;HUVEC TERT2: 54.8;RT4: 14.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA064878, HPA067180" Enhanced Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA064878: AB_2685380, HPA067180: AB_2685797" "unprognostic (7.76e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (8.01e-2)" "unprognostic (8.47e-2)" "unprognostic (9.82e-3)" "prognostic favorable (3.29e-4)" "unprognostic (1.35e-1)" "unprognostic (6.60e-2)" "unprognostic (3.00e-2)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (7.96e-4)" "unprognostic (1.61e-4)" "unprognostic (2.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.69e-1)" 23.3 5.5 1.3 2.6 5.5 0.0 15.9 5.1 3.2 10.5 3.1 8.0 2.2 5.9 2.8 5.9 11.3 10.1 17.5 1.1 4.1 3.6 77.9 10.9 5.0 14.3 3.0 29.8 2.3 1.3 2.1 2.1 9.4 2.9 4.4 0.8 9.0 2.0 5.4 6.6 5.5 3.7 7.1 1.5 5.7 1.8 3.4 1.4 8.6 11.7 3.2 14.2 8.9 21.3 0.0 0.0 0.0 0.0 39.9 56.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 25.3 0.1 3.2 0.9 1.5 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 2.5 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 5.5 5.1 3.2 1.1 4.1 14.3 3.0 9.4 7.1 3.4 21.3 12.5 0.0 0.0 2.9 2.0 3.1 1.5 0.4 4.0 11.6 1.8 2.2 6.0 4.3 0.9 3.7 6.2 0.0 1.7 1.8 0.0 0.5 3.3 0.7 5.1 3.2 2.4 2.7 62.5 0.2 0.0 117.6 2.0 2.5 0.0 4.0 3.3 110.3 1.6 0.0 77.8 0.7 0.0 2.5 42.1 2.7 51.3 20.3 5.4 93.7 0.7 3.2 0.0 4.5 33.4 0.4 1.1 12.0 1.2 0.1 0.5 0.9 0.7 13.3 0.0 20.0 14.3 2.0 0.9 1.4 2.8 0.0 1.2 45.4 0.3 0.5 ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 231.5;Granulosa cells: 117.3;Leydig cells: 502.6;Microglial cells: 162.1;Oligodendrocytes: 406.6;Skeletal myocytes: 216.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 31.9;ASC TERT1: 69.6;HSkMC: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" 39.1 30.5 12.6 2.8 28.1 0.0 21.3 21.0 18.3 10.0 9.6 16.4 6.2 11.9 15.6 7.6 23.7 16.9 42.1 13.6 16.1 9.5 33.7 18.2 1.1 28.2 19.8 51.5 5.7 3.8 11.1 9.0 29.0 9.5 16.9 9.2 14.8 8.6 12.3 6.2 11.8 6.6 20.7 12.4 14.3 19.5 18.4 4.5 17.0 26.7 3.0 16.3 14.6 58.1 0.0 0.0 3.9 0.0 31.9 69.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 12.0 0.0 0.0 53.5 0.0 0.8 0.0 0.4 6.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 28.1 21.0 18.3 13.6 16.1 28.2 19.8 29.0 20.7 18.4 58.1 22.6 51.3 1.1 0.7 0.0 6.0 1.8 0.0 2.8 5.0 0.7 1.0 18.8 0.0 4.3 0.0 2.1 0.2 0.3 0.0 0.0 0.0 4.8 0.4 14.0 6.8 0.0 0.0 0.5 0.0 0.1 231.5 3.1 0.3 1.3 117.3 5.7 48.1 1.1 5.0 0.6 0.0 0.0 1.9 9.4 19.4 502.6 2.6 1.8 162.1 0.0 100.3 0.0 0.5 406.6 0.0 0.0 70.3 1.9 0.4 0.0 0.1 0.0 3.3 39.5 216.6 44.5 5.1 1.7 2.5 4.7 0.3 2.1 60.9 0.0 0.4 ABCA9 EST640918 ENSG00000154258 "ATP binding cassette subfamily A member 9" Q8IUA7 17 68974488-69060949 "Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.5;Fibroblasts: 86.6;Inhibitory neurons: 73.2;Leydig cells: 96.3;Microglial cells: 227.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 21.8;ASC TERT1: 47.7;HSkMC: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052113, HPA054823" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA052113: AB_2732573, HPA054823: AB_2682615" "unprognostic (3.88e-2)" "unprognostic (9.86e-2)" "unprognostic (2.21e-1)" "unprognostic (9.75e-2)" "unprognostic (4.46e-1)" "unprognostic (5.64e-3)" "unprognostic (4.51e-4)" "unprognostic (1.83e-2)" "unprognostic (1.94e-3)" "unprognostic (7.86e-2)" "unprognostic (3.26e-3)" "unprognostic (3.51e-1)" "unprognostic (7.77e-6)" "unprognostic (5.32e-4)" "unprognostic (7.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-3)" 33.7 4.1 2.8 1.4 5.1 1.8 22.3 7.7 8.0 14.7 6.3 12.4 1.8 11.2 8.9 4.8 20.6 8.2 22.6 3.0 1.4 2.7 11.9 8.8 2.3 3.1 1.2 27.4 3.5 2.3 4.9 1.2 4.5 3.3 4.0 8.4 9.0 2.8 13.1 9.2 6.6 6.6 1.2 1.6 7.8 5.2 3.5 2.5 11.1 10.6 1.1 10.9 12.7 7.7 0.2 0.4 0.8 0.8 21.8 47.7 0.6 0.4 0.4 0.0 0.4 0.5 0.5 0.6 0.2 0.8 0.3 0.5 0.4 0.7 0.2 0.3 0.4 0.6 2.4 0.6 2.3 0.9 1.3 17.0 0.5 3.6 0.3 0.9 4.8 0.6 0.8 1.3 0.1 0.3 0.3 2.1 0.3 0.2 0.4 2.2 0.1 0.3 0.3 1.9 0.7 0.6 0.5 0.3 0.3 0.4 0.4 0.8 2.0 1.3 0.5 2.3 0.5 1.0 0.5 0.4 0.4 0.5 2.4 0.5 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.4 0.2 0.0 0.1 0.0 0.0 2.8 5.1 7.7 8.0 3.0 1.4 3.1 1.2 4.5 1.2 3.5 7.7 7.4 0.0 1.5 2.6 0.5 1.8 0.3 0.1 1.2 3.9 0.7 0.8 3.9 1.5 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.1 1.3 0.4 2.1 2.6 0.0 0.0 55.5 0.0 0.0 86.6 2.0 1.4 0.0 2.2 18.5 11.4 0.3 0.0 73.2 0.1 0.0 1.3 5.1 3.6 96.3 4.9 0.0 227.7 0.0 7.9 1.0 6.0 10.9 0.2 0.0 15.4 0.2 0.1 0.3 0.0 1.7 5.6 13.1 26.3 7.1 1.3 0.8 1.3 1.6 0.0 0.5 26.3 0.1 0.3 ABCB5 "ABCB5alpha, ABCB5beta, EST422562" ENSG00000004846 "ATP binding cassette subfamily B member 5" Q2M3G0 7 20615207-20777038 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "epididymis: 26.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.8;Early spermatids: 8.1;Fibroblasts: 2.4" "Cancer enriched" "Detected in some" 9 "melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 47.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.82e-1)" "unprognostic (1.57e-1)" "unprognostic (2.55e-3)" "unprognostic (1.55e-2)" "unprognostic (1.14e-2)" "unprognostic (2.98e-1)" "unprognostic (2.60e-3)" "unprognostic (1.65e-2)" "unprognostic (2.05e-1)" "unprognostic (2.63e-1)" "unprognostic (6.23e-2)" "unprognostic (5.26e-3)" "unprognostic (3.56e-3)" "unprognostic (9.30e-4)" "unprognostic (1.29e-1)" "unprognostic (1.80e-2)" "unprognostic (2.70e-2)" 2.0 0.0 0.2 0.2 0.2 0.4 2.1 0.4 0.2 1.5 0.2 1.3 0.1 0.6 26.4 0.1 0.2 2.7 0.3 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.1 0.2 0.2 0.5 0.1 0.1 0.3 0.1 0.8 0.4 0.6 0.1 0.0 0.2 0.5 0.2 0.0 0.0 0.1 0.0 0.7 0.5 0.4 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 6.6 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 47.8 0.0 0.0 0.2 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.4 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.2 0.4 0.1 0.0 0.5 0.3 0.0 0.5 2.8 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 8.1 0.3 0.2 0.4 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.1 1.3 0.0 0.0 0.0 0.3 0.0 1.7 0.0 0.0 0.0 1.5 1.0 0.6 0.4 1.8 1.9 0.0 0.2 1.0 1.0 0.6 0.0 0.0 0.4 0.0 0.9 0.0 0.1 0.0 0.3 0.0 1.7 0.6 0.6 0.4 0.0 0.6 0.0 0.6 0.0 0.0 0.8 ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713016-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 71.2;Oligodendrocytes: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Yes No "Cluster 37: B-cells - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 50.9 30.7 27.4 25.3 38.9 23.4 45.8 33.6 31.4 60.5 40.4 96.4 23.1 63.0 11.6 33.8 55.6 35.7 36.1 26.6 28.3 23.1 17.5 37.3 16.3 39.3 38.5 56.0 24.9 32.5 34.9 26.5 35.8 43.5 26.7 14.2 32.4 33.6 29.4 36.3 45.2 41.2 31.3 23.3 51.6 20.1 34.9 22.4 46.7 30.8 15.4 79.3 42.7 41.3 22.5 48.3 53.6 62.9 76.5 93.3 18.8 38.8 60.4 44.8 38.1 36.4 28.3 32.3 22.3 52.0 47.6 42.5 23.5 36.0 30.7 20.6 16.3 23.7 84.1 33.4 51.8 36.5 32.3 68.8 37.2 80.6 50.0 64.1 61.0 47.9 135.8 26.5 54.9 42.0 49.2 30.5 57.9 34.3 33.8 55.9 67.9 35.9 45.0 25.7 47.9 60.1 66.1 23.5 29.2 31.0 46.2 33.1 71.1 170.7 44.1 66.3 62.6 8.4 20.3 47.9 72.1 27.6 55.1 0.0 0.7 0.3 0.6 0.4 0.8 1.3 0.6 0.6 0.7 0.4 0.6 0.5 0.0 0.8 1.9 1.0 0.3 0.6 27.4 38.9 33.6 31.4 26.6 28.3 39.3 38.5 35.8 31.3 34.9 41.3 16.2 9.6 13.6 54.9 4.7 9.2 7.3 9.8 5.2 8.2 11.6 10.2 6.2 7.2 7.2 14.7 12.5 13.6 12.1 21.2 1.9 14.4 5.9 8.6 29.7 18.1 22.1 4.6 52.5 11.1 4.3 36.7 5.6 12.4 2.5 22.1 20.3 15.9 16.6 10.1 63.7 17.5 6.1 16.4 11.7 8.8 28.0 10.2 5.4 71.2 6.6 19.2 6.2 66.9 116.0 17.9 18.3 25.6 5.6 8.6 11.6 10.3 7.8 9.1 19.7 29.5 19.8 16.9 16.5 6.6 6.8 15.2 7.9 20.1 21.4 7.2 AC002456.2 ENSG00000251154 "Uncharacterized LOC102723899" 7 90469639-90513397 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 69 "testis: 9.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.4;Basal respiratory cells: 3.0;Cholangiocytes: 2.8;Hepatocytes: 3.3;Melanocytes: 1.8;Spermatogonia: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Fibroblasts - ECM organization" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.4 3.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.1 0.6 0.8 1.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.5 1.3 0.8 2.7 0.0 0.3 0.0 0.0 0.0 0.0 0.4 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.6;Endothelial cells: 59.8;Fibroblasts: 171.2;Smooth muscle cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HeLa: 103.7;MCF7: 80.0;RT4: 312.3;SiHa: 97.0;U-2197: 328.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" 116.2 5.2 13.0 14.3 13.5 3.5 70.4 13.1 15.6 29.2 18.3 38.7 11.8 17.3 10.5 25.0 33.7 30.8 68.5 13.7 18.9 11.3 28.3 26.3 10.5 22.3 16.0 15.9 37.9 5.0 24.4 123.3 14.4 20.1 24.7 1.7 21.4 16.8 35.4 38.1 34.1 24.2 14.3 56.0 27.9 14.6 14.5 6.4 58.1 37.9 5.6 107.0 38.2 13.6 0.0 0.1 6.3 0.0 10.5 0.2 44.9 2.6 1.4 2.3 4.6 0.5 0.1 0.0 5.1 0.2 16.9 68.0 0.2 24.0 0.4 0.1 0.0 0.1 103.7 0.2 0.1 0.2 0.1 3.2 61.0 0.3 0.0 15.4 11.2 0.3 1.2 0.1 0.0 80.0 0.2 0.2 11.0 0.0 0.7 0.1 7.6 0.8 0.0 312.3 0.4 0.1 97.0 0.5 0.0 23.9 0.0 0.3 0.0 0.8 23.3 328.5 0.1 1.4 0.0 0.1 1.2 6.6 0.5 0.0 0.1 0.0 2.5 0.2 3.8 0.3 1.3 3.2 0.1 0.6 1.1 1.5 0.0 4.7 0.4 0.0 2.0 0.5 13.0 13.5 13.1 15.6 13.7 18.9 22.3 16.0 14.4 14.3 14.5 13.6 33.2 9.6 4.8 20.5 1.1 22.0 0.2 39.6 1.2 1.7 0.2 1.0 9.1 0.0 24.8 0.0 0.0 0.1 0.7 1.0 0.0 0.2 0.9 13.5 24.2 59.8 0.0 0.0 0.7 10.4 0.8 171.2 1.1 24.8 6.3 6.3 33.5 2.5 0.8 0.0 2.3 0.1 6.1 4.1 10.1 0.4 1.5 6.9 1.8 12.2 0.8 0.1 1.0 1.0 0.1 1.3 5.3 1.2 0.5 0.5 3.3 0.9 5.8 0.1 0.0 35.7 37.1 0.2 0.3 1.1 15.9 0.3 1.5 1.1 0.2 2.6 ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Fibroblasts: 21.4;Proximal enterocytes: 19.1;Respiratory ciliated cells: 15.7" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "BJ hTERT+: 285.1" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" 11.1 1.4 0.6 1.0 0.2 0.8 5.5 0.3 0.3 0.7 0.9 1.9 15.8 3.7 1.7 1.4 2.0 6.5 5.7 0.4 0.0 1.1 1.0 8.0 2.1 0.3 0.5 1.0 2.6 0.0 6.7 0.2 0.3 0.5 1.3 0.6 7.1 1.9 0.5 8.9 13.0 2.2 0.3 1.6 10.2 0.4 0.1 0.5 1.4 1.0 1.6 4.6 1.1 0.2 0.2 0.0 0.2 0.2 19.9 10.7 0.1 47.7 285.1 2.8 7.9 0.2 0.4 3.3 0.0 29.9 0.2 0.1 0.0 0.0 1.8 1.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 1.3 0.0 0.0 4.9 0.1 0.2 0.6 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.1 0.1 0.2 0.0 0.5 0.1 0.7 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.3 0.4 0.0 0.3 0.5 0.3 0.3 0.1 0.2 1.6 38.5 1.1 0.7 0.1 6.5 0.6 1.3 0.0 1.6 0.3 0.3 0.7 1.5 2.3 5.5 6.2 0.2 0.1 1.1 0.0 0.2 2.9 2.9 0.6 3.9 0.0 0.0 0.6 12.1 0.1 21.4 10.7 0.6 0.0 0.7 9.7 0.2 0.4 1.7 0.5 0.8 0.0 0.3 5.1 0.4 2.1 0.3 1.8 1.9 6.8 0.9 0.0 0.0 0.3 5.1 0.1 2.6 0.5 0.4 19.1 3.0 15.7 3.4 0.0 1.3 2.6 0.1 0.1 0.6 6.5 0.3 0.5 12.5 3.7 1.2 ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.6;lymphoid tissue: 2.6;skin 1: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 33.3;U-87 MG: 45.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" 0.0 0.0 1.7 0.0 3.3 0.0 0.2 6.6 2.7 0.7 0.8 0.0 0.0 0.0 0.4 0.7 0.0 0.2 0.0 2.0 2.2 0.0 0.0 0.0 0.0 3.9 3.7 0.0 0.0 0.3 0.0 0.0 3.8 0.3 0.0 0.0 0.5 0.0 0.0 6.0 0.0 0.0 2.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 2.6 0.1 0.6 4.1 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.6 0.8 0.4 5.2 0.0 0.0 0.0 33.3 0.3 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.5 0.3 0.0 0.1 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.1 1.1 0.0 0.0 0.0 0.0 0.0 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.3 6.6 2.7 2.0 2.2 3.9 3.7 3.8 2.0 3.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157876330 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" 20.8 10.4 17.3 12.9 12.7 1.8 18.8 14.0 15.4 28.1 17.4 16.5 10.9 24.4 32.7 11.3 17.0 24.2 19.7 26.3 12.8 26.4 22.7 17.5 8.8 13.7 12.9 21.2 10.0 8.5 10.9 17.6 13.7 15.1 12.6 6.3 18.8 15.3 21.5 13.9 10.5 34.5 12.6 8.3 14.7 5.2 16.3 7.5 40.5 13.3 8.2 20.9 15.5 11.8 6.1 13.1 14.4 18.5 65.0 70.6 18.9 43.4 71.3 33.7 36.1 10.1 13.4 0.2 18.2 45.6 32.3 16.9 10.5 22.5 36.8 43.0 8.7 25.7 7.2 14.4 54.7 2.0 28.5 89.5 41.4 69.8 84.2 42.8 38.7 6.7 9.5 6.7 45.2 11.1 0.4 0.4 21.4 8.7 21.7 4.1 19.6 5.7 45.4 24.5 12.4 14.9 17.0 9.7 64.5 22.2 5.3 7.0 54.0 50.9 16.8 25.3 17.1 4.7 3.5 0.3 52.2 1.6 58.1 2.9 1.7 0.1 0.5 1.0 0.7 0.8 4.9 1.3 1.3 0.2 1.6 0.7 0.2 1.2 1.4 1.4 6.6 1.1 17.3 12.7 14.0 15.4 26.3 12.8 13.7 12.9 13.7 12.6 16.3 11.8 9.6 9.6 9.0 22.9 1.8 9.8 7.7 12.6 12.5 10.4 8.0 9.8 12.7 11.5 12.4 7.3 0.0 8.4 1.1 4.8 5.9 9.9 1.0 5.9 12.9 17.3 4.2 1.7 34.0 17.8 5.3 20.3 8.2 6.5 5.1 4.2 18.2 13.3 7.0 3.3 34.2 4.5 24.4 13.0 8.7 2.0 20.2 7.6 3.6 106.8 5.5 6.6 2.1 42.3 22.9 17.2 4.1 15.8 6.4 13.0 3.7 15.5 13.6 2.1 13.1 16.3 19.3 0.4 2.7 4.0 7.5 10.5 4.3 3.5 4.3 8.8 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTS5 "ADAMTS11, ADMP-2" ENSG00000154736 "ADAM metallopeptidase with thrombospondin type 1 motif 5" Q9UNA0 21 26917922-26967088 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 26.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 38.2;Endometrial stromal cells: 72.1;Fibroblasts: 88.6;Leydig cells: 62.7;Skeletal myocytes: 110.2;Smooth muscle cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.9;fHDF/TERT166: 11.9;RH-30: 33.1;U-87 MG: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA005661, CAB025996, HPA030906, HPA030908" Approved Supported Nucleoplasm "Secreted to extracellular matrix" NA NA 28000 "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB025996: , HPA005661: AB_1078101, HPA030906: AB_2673654, HPA030908: AB_2673655" "unprognostic (1.97e-1)" "unprognostic (2.88e-3)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (4.67e-1)" "unprognostic (2.10e-2)" "unprognostic (4.38e-8)" "unprognostic (1.11e-3)" "unprognostic (7.66e-2)" "unprognostic (6.17e-2)" "unprognostic (8.13e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (6.69e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.15e-1)" 17.5 0.8 0.3 1.0 0.6 0.0 10.8 3.3 0.3 8.8 2.6 2.7 0.8 12.5 2.4 1.6 4.2 1.6 3.3 0.5 0.9 2.5 1.4 1.0 0.6 1.4 0.9 16.6 0.4 1.5 0.4 26.2 0.9 3.0 1.3 0.6 2.0 1.8 2.0 4.2 3.4 7.5 1.5 7.7 2.2 0.8 0.4 0.3 6.8 3.7 0.1 4.2 3.6 1.2 0.0 0.0 0.0 0.0 31.6 13.9 0.0 1.7 0.2 1.4 0.6 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.3 0.0 3.5 0.1 0.0 8.0 0.0 1.1 0.2 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 33.1 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.3 0.4 1.9 0.9 0.0 0.0 0.0 13.0 0.1 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.3 0.3 0.5 0.9 1.4 0.9 0.9 1.5 0.4 1.2 24.3 0.0 0.5 0.3 0.1 2.9 0.2 0.4 0.0 9.8 1.5 38.2 2.7 0.0 0.6 3.7 0.0 1.1 0.3 0.0 0.0 0.0 6.4 2.0 72.1 10.6 1.8 0.0 0.5 0.2 1.6 88.6 0.0 1.3 0.0 3.0 3.3 0.0 1.9 0.0 11.6 0.0 0.0 0.0 4.6 1.0 62.7 1.4 3.6 3.7 4.0 0.1 0.0 12.5 0.2 0.0 0.0 9.1 0.0 0.3 0.0 2.2 0.0 0.2 13.1 110.2 44.9 0.3 0.9 0.4 3.0 2.7 0.8 20.0 0.0 0.1 ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Endothelial cells: 5.7;Fibroblasts: 8.5;Microglial cells: 12.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 7.4;RPMI-8226: 10.1;SH-SY5Y: 30.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" 3.7 28.5 6.8 1.0 7.3 0.1 1.5 12.0 10.1 2.3 1.4 2.7 1.4 3.1 3.1 1.8 3.1 2.5 73.2 5.8 7.9 25.9 35.8 23.2 3.4 19.3 11.1 4.9 7.1 1.2 15.9 1.5 20.8 8.4 0.3 0.3 3.4 2.2 4.3 0.8 3.2 0.9 8.5 6.4 2.3 3.1 9.3 0.6 12.1 0.5 0.6 5.3 1.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.5 0.0 1.1 0.7 10.1 0.0 0.0 1.4 30.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.3 12.0 10.1 5.8 7.9 19.3 11.1 20.8 8.5 9.3 7.6 1.4 0.0 0.5 4.9 0.1 0.1 0.1 0.0 0.0 4.2 0.0 0.1 2.3 0.0 0.0 1.8 0.0 0.1 0.0 1.4 5.9 0.2 0.1 0.1 0.1 5.7 5.3 0.0 5.0 0.0 0.1 8.5 0.0 0.0 0.0 0.1 4.6 0.9 0.3 0.0 3.8 0.4 0.0 0.3 0.8 1.1 4.7 0.6 0.0 12.2 0.0 0.4 0.0 2.5 4.0 0.2 0.5 3.0 0.0 0.2 0.0 0.7 0.0 0.2 6.6 1.1 1.6 0.1 0.8 0.4 0.3 0.0 0.6 0.7 1.1 0.2 ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 449.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.2;ASC TERT1: 292.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 260000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB009797: AB_2223583, HPA035696: AB_2674740" "unprognostic (2.66e-1)" "unprognostic (2.63e-2)" "unprognostic (1.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-2)" "unprognostic (1.57e-3)" "unprognostic (6.42e-2)" "unprognostic (5.73e-2)" "unprognostic (2.37e-2)" "unprognostic (7.58e-2)" "unprognostic (9.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.36e-1)" "unprognostic (4.03e-1)" "unprognostic (3.68e-2)" "unprognostic (5.92e-2)" 57.7 21.7 105.6 38.8 97.2 37.5 89.4 88.6 129.3 57.6 65.9 58.2 71.9 24.9 62.4 39.0 47.6 72.0 59.9 113.3 108.1 102.7 27.8 38.4 70.9 107.3 94.8 46.4 67.9 18.8 25.3 36.6 102.0 32.7 66.0 99.4 59.1 31.8 9.6 33.6 85.4 23.9 105.2 40.0 63.7 51.5 95.6 87.4 87.7 25.6 65.4 42.3 40.1 122.4 29.2 6.0 41.7 19.8 313.2 292.1 17.7 41.2 110.9 25.4 49.9 60.3 90.6 89.9 45.2 63.9 26.4 10.0 37.3 27.1 39.5 9.0 46.5 8.8 28.5 45.9 35.5 30.5 66.0 142.5 12.9 63.3 2.6 96.4 37.8 109.9 23.5 48.7 46.7 0.8 32.3 31.0 25.8 69.2 15.3 27.7 58.2 4.8 65.7 14.2 6.1 67.9 27.6 8.9 66.5 62.2 10.7 11.4 9.5 16.0 42.0 33.5 9.1 68.9 31.5 82.7 47.8 16.2 27.7 139.5 29.6 98.0 68.8 26.5 55.7 51.4 72.9 59.1 24.8 42.9 83.2 67.6 47.1 73.4 32.6 16.3 73.3 94.9 105.6 97.2 88.6 129.3 113.3 108.1 107.3 94.8 102.0 105.2 95.6 122.4 67.3 22.4 52.9 449.2 110.6 55.7 35.9 77.4 38.7 26.8 56.0 34.4 128.2 74.4 85.5 36.8 60.5 55.6 112.7 125.2 60.7 27.2 51.4 70.3 76.0 77.7 102.4 32.6 83.4 61.1 12.1 182.4 100.9 56.0 26.0 18.8 126.7 12.2 25.7 116.1 141.1 71.6 48.8 88.5 41.1 25.7 226.5 66.3 58.7 70.3 65.3 339.0 151.4 236.8 279.6 59.8 167.1 251.3 68.4 38.4 135.2 162.2 151.9 121.7 65.7 27.6 36.2 122.7 62.1 53.2 50.6 22.3 111.5 30.9 166.7 98.6 ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 30.5;Cardiomyocytes: 47.0;Early spermatids: 16.2;Endometrial stromal cells: 50.2;Fibroblasts: 32.7;Late spermatids: 21.4;Leydig cells: 13.7;Microglial cells: 25.3;Peritubular cells: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Cell line enhanced" "Detected in some" "BJ: 4.1;fHDF/TERT166: 4.7;HeLa: 7.6;HHSteC: 4.9;HMC-1: 13.0;U-2 OS: 6.1" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" 26.4 1.9 1.9 1.3 2.0 0.3 10.3 1.2 2.5 20.6 1.0 10.6 1.9 15.4 7.3 6.9 17.7 12.9 62.4 1.4 3.2 3.4 10.3 35.6 0.4 2.0 2.6 17.9 12.0 0.3 6.3 25.7 2.2 15.3 1.8 0.8 2.9 1.0 7.3 7.0 12.1 7.1 2.0 2.3 20.7 7.5 3.6 0.4 11.2 8.5 1.0 40.3 16.3 1.7 0.0 0.7 0.0 2.0 0.0 0.0 0.1 4.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.6 0.0 4.9 0.0 13.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.8 0.0 0.1 0.2 2.1 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.4 6.1 1.5 0.1 0.1 1.7 0.8 0.1 0.0 0.0 0.0 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 1.9 2.0 1.2 2.5 1.4 3.2 2.0 2.6 2.2 2.0 3.6 1.7 2.0 22.4 30.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 47.0 0.0 5.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 16.2 1.3 50.2 3.4 0.0 0.0 1.1 0.4 0.6 32.7 0.5 1.0 1.3 0.3 1.8 3.6 2.3 0.0 1.4 0.0 0.0 1.5 0.0 21.4 13.7 1.5 0.0 25.3 3.5 0.0 0.0 0.0 0.1 0.3 0.0 15.8 0.0 0.0 0.0 0.1 2.2 0.7 6.6 2.2 3.5 4.3 6.5 0.1 0.0 1.0 0.6 0.2 0.1 0.3 ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1227.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Endometrial stromal cells: 5.4;Fibroblasts: 5.3;Gastric mucus-secreting cells: 9.2;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.0;BEWO: 7.3;HeLa: 5.9;NTERA-2: 6.4;RPMI-8226: 4.5;SH-SY5Y: 6.6;U-2197: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" 3.9 0.3 0.1 0.9 0.1 0.0 2.0 0.0 1.1 1.0 0.0 0.5 0.5 1.0 1227.7 0.5 16.5 1.6 1.3 0.8 0.7 0.4 0.7 1.3 5.0 0.4 1.5 0.2 1.2 163.4 1.1 0.5 0.6 2.1 0.4 0.9 8.5 3.6 0.2 0.4 1.1 0.4 0.1 2.4 9.0 1.9 0.3 6.6 1.6 1.1 3.7 0.8 1.0 0.2 0.2 6.0 0.0 0.0 0.1 0.9 7.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.4 0.0 5.9 0.2 0.8 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 2.2 6.4 0.0 2.0 0.0 0.0 4.5 0.0 1.2 2.2 6.6 1.5 0.1 0.0 1.1 0.1 0.1 0.1 0.2 0.4 14.6 2.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.8 0.7 0.4 1.5 0.6 0.1 0.3 0.2 0.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.0 0.6 1.2 1.1 1.0 7.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.1 1.1 5.4 0.6 0.0 0.0 4.4 0.2 0.3 5.3 9.2 3.2 0.0 0.2 1.4 0.4 0.0 3.3 5.0 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.0 4.7 0.0 4.8 0.0 10.1 7.0 3.1 0.0 1.5 0.0 3.4 0.0 0.1 2.2 0.7 0.0 1.6 0.6 0.1 1.4 0.1 0.0 0.0 0.3 0.3 0.0 0.3 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.6;placenta: 141.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 53.1;Hepatocytes: 30.9;Leydig cells: 145.1;Sertoli cells: 144.7;Smooth muscle cells: 71.2" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enhanced" "Detected in some" "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 176.8;ASC TERT1: 24.4;BJ hTERT+ SV40 Large T+: 34.8;HBF TERT88: 53.9;HSkMC: 32.2" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 65.9 38.2 0.3 1.8 0.7 0.0 39.9 0.2 0.4 3.4 0.4 21.1 0.8 3.5 2.7 2.8 9.8 6.2 10.9 0.4 1.4 18.4 96.6 10.4 0.7 2.1 8.1 3.8 3.5 2.8 3.8 141.6 0.9 5.3 4.4 0.9 4.7 4.2 11.6 15.8 4.3 4.6 0.2 9.1 6.5 2.2 0.7 3.0 14.2 13.8 0.2 14.6 6.1 0.2 0.0 1.0 0.8 0.0 176.8 24.4 0.0 0.2 3.9 34.8 20.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.2 0.0 3.4 1.8 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.2 0.4 0.4 1.4 2.1 8.1 0.9 0.2 0.7 0.2 20.5 0.0 0.6 0.0 0.0 3.4 0.2 0.0 0.0 0.0 1.3 0.9 6.3 2.8 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.1 0.8 0.0 0.3 3.8 23.5 0.0 0.1 7.6 0.3 53.1 0.5 0.0 0.0 0.0 17.5 30.9 0.7 0.0 0.0 0.2 0.0 0.3 3.5 1.7 145.1 0.5 1.8 2.8 0.0 5.7 0.0 0.0 0.1 0.5 0.0 7.5 0.4 1.1 0.0 0.1 0.0 0.1 144.7 7.6 71.2 0.0 1.8 0.3 1.7 0.3 0.5 0.3 0.0 0.1 AHNAK MGC5395 ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 561.4;fHDF/TERT166: 554.5;TIME: 582.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 395.4" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 10000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA019010: AB_1844657, HPA019070: AB_1844656, HPA026643: AB_10670426" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (3.46e-1)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.84e-2)" "unprognostic (1.98e-3)" "prognostic unfavorable (2.42e-4)" "unprognostic (4.30e-1)" "unprognostic (4.49e-3)" "unprognostic (5.42e-2)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.47e-6)" 243.1 27.9 62.6 43.4 50.2 44.1 190.3 33.7 45.4 183.3 61.0 276.2 49.0 183.3 51.7 248.2 145.5 74.8 115.1 65.0 98.0 59.7 60.1 144.1 36.7 76.2 48.3 125.8 30.3 26.3 16.9 97.3 62.9 88.5 96.6 10.1 127.5 105.7 188.5 334.7 136.6 113.1 60.8 59.5 133.5 18.0 49.0 27.9 64.9 172.2 63.7 142.0 213.3 78.4 188.2 107.9 9.8 44.1 421.8 561.4 70.3 166.0 201.4 103.0 57.4 93.7 64.9 0.2 61.7 554.5 79.8 244.1 41.2 203.7 130.7 154.2 7.3 22.6 173.4 27.9 80.8 31.5 142.2 204.2 233.0 202.4 183.6 131.5 215.4 2.7 21.8 138.8 211.7 72.1 0.4 60.7 3.0 59.6 171.7 0.4 45.1 113.9 227.1 120.2 0.3 9.2 167.5 69.3 69.0 198.8 133.7 28.4 582.1 182.4 119.8 229.8 74.4 25.0 5.4 0.6 138.2 10.1 60.9 44.1 75.6 0.3 38.7 45.0 25.8 20.0 24.8 31.7 73.8 16.1 3.2 17.3 1.1 31.5 37.8 20.2 21.5 36.8 62.6 50.2 33.7 45.4 65.0 98.0 76.2 48.3 62.9 60.8 49.0 78.4 413.1 439.1 106.3 49.3 171.4 479.4 133.8 285.0 253.2 1.4 173.0 226.8 199.9 195.9 224.1 193.1 0.0 110.8 194.3 400.8 13.7 99.6 10.6 188.5 195.0 282.5 47.6 43.7 0.9 64.1 145.6 312.9 538.2 351.2 238.9 4.3 201.4 88.5 79.4 1.7 0.8 164.8 138.4 329.8 458.3 33.2 451.4 292.3 318.4 43.1 284.8 30.7 138.0 0.5 0.4 262.5 195.5 466.0 329.0 202.4 262.3 6.8 149.3 1.2 177.5 349.5 244.4 3.1 8.1 596.4 610.3 102.2 256.5 3.0 101.8 198.0 AICDA "AID, ARP2, CDA2, HIGM2" ENSG00000111732 "Activation induced cytidine deaminase" Q9GZX7 12 8602170-8612867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 15.4" "Cell type enhanced" "Detected in single" "Proximal enterocytes: 2.6" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 1.9;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 6 "B-cells: 3.8" "Group enriched" "Detected in some" 7 "Daudi: 142.5;U-698: 118.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.71e-2)" "unprognostic (1.39e-2)" "unprognostic (7.76e-2)" "unprognostic (1.68e-1)" "unprognostic (8.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.05e-2)" "unprognostic (9.69e-2)" "unprognostic (1.96e-2)" "unprognostic (4.04e-6)" "unprognostic (8.82e-2)" "unprognostic (1.28e-1)" "unprognostic (4.21e-1)" "unprognostic (4.65e-1)" 0.2 0.1 0.4 3.7 0.3 0.6 0.0 1.2 0.6 0.0 0.1 0.2 0.2 0.2 0.2 0.2 0.0 0.5 0.3 0.3 0.1 0.0 0.1 0.2 15.4 0.2 0.3 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.1 0.2 0.3 0.0 1.4 0.3 0.8 0.0 0.0 0.7 0.2 0.2 0.3 0.4 0.2 0.0 12.0 0.1 0.1 0.6 0.1 0.0 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 142.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 5.3 0.2 0.1 0.0 2.0 19.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.2 0.5 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.1 1.3 0.1 0.1 0.6 0.1 0.4 0.5 0.1 0.0 0.1 118.4 0.0 0.3 0.1 0.5 0.2 0.1 0.1 0.1 0.0 1.9 0.1 0.0 0.1 3.8 0.1 0.1 0.6 0.1 0.1 0.2 0.1 0.2 0.4 0.3 1.2 0.6 0.3 0.1 0.2 0.3 0.3 0.0 0.3 0.6 0.2 0.0 0.6 0.0 0.9 0.3 0.6 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.6 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.6 0.2 0.0 0.7 0.0 0.8 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.1 0.3 AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 166.7" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Fibroblasts: 2.9;Late spermatids: 3.6;Skeletal myocytes: 12.5;Syncytiotrophoblasts: 10.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 15.8;HDLM-2: 12.8;Hep G2: 11.2;SK-BR-3: 5.1;U-87 MG: 6.7" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Breast - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favorable (8.36e-4)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.90e-5)" 0.4 0.1 0.4 0.2 1.4 0.0 166.7 0.3 0.5 1.1 0.0 0.8 14.0 0.0 0.2 3.2 0.0 5.2 0.1 0.4 1.1 0.1 2.1 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.6 0.3 1.8 0.0 7.8 1.1 4.5 0.0 0.7 0.0 12.0 0.5 1.4 0.2 0.1 18.8 0.3 0.9 2.6 1.5 0.1 15.8 0.1 0.0 0.6 0.5 0.9 0.0 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.7 0.1 0.0 0.1 0.0 12.8 0.0 0.1 0.2 11.2 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.2 3.1 0.4 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.6 5.1 0.0 0.1 0.0 0.3 0.0 0.1 0.7 0.3 0.0 0.2 0.2 0.2 6.7 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.5 0.4 1.1 0.6 1.1 0.6 0.7 1.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.5 0.1 0.0 0.7 0.0 0.3 10.4 0.1 0.0 0.0 0.1 ALDH1L2 "FLJ38508, mtFDH" ENSG00000136010 "Aldehyde dehydrogenase 1 family member L2" Q3SY69 12 105019784-105107643 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 40.7;salivary gland: 13.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 23.1;Inhibitory neurons: 24.0;Oligodendrocyte precursor cells: 25.1;Plasma cells: 14.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.8;ASC TERT1: 85.2;fHDF/TERT166: 102.4;HHSteC: 55.6;HSkMC: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039481, HPA059282" Approved Enhanced Mitochondria No No "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA039481: AB_10795465, HPA059282: AB_2732633" "unprognostic (5.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.76e-1)" "unprognostic (8.86e-2)" "unprognostic (1.75e-1)" "unprognostic (2.92e-1)" "unprognostic (5.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-8)" "unprognostic (3.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.53e-3)" "unprognostic (2.52e-5)" 3.7 0.6 1.3 3.1 1.2 0.6 2.3 2.3 1.6 5.3 0.7 2.2 2.6 2.0 1.0 1.3 1.5 2.8 1.9 1.1 1.6 0.4 0.2 1.8 1.0 1.4 1.3 0.6 40.7 0.6 1.3 1.1 1.5 3.6 2.3 0.7 13.0 4.6 0.8 1.0 1.4 4.2 1.8 0.7 3.3 1.1 1.6 0.5 2.1 1.2 1.7 3.4 1.5 2.5 13.0 1.3 0.7 27.3 62.8 85.2 1.6 40.8 26.0 5.2 13.5 1.6 0.0 0.0 1.6 102.4 0.2 0.1 0.1 1.0 6.5 0.0 0.3 0.8 0.1 3.4 55.6 5.3 0.1 69.7 3.1 13.6 25.2 0.0 3.0 0.2 2.1 37.7 10.6 0.0 0.0 0.3 1.6 0.0 0.3 0.0 0.1 4.3 0.0 0.0 9.4 4.5 0.0 8.3 20.5 0.4 6.0 44.0 0.3 3.9 3.8 0.0 2.2 45.5 12.8 0.1 16.2 19.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.2 2.3 1.6 1.1 1.6 1.4 1.3 1.5 1.8 1.6 2.5 1.4 0.0 0.6 3.3 2.6 0.5 0.1 0.7 0.0 1.7 0.3 1.1 1.6 0.0 0.2 0.0 0.0 0.2 1.5 0.1 0.0 0.3 4.1 0.7 8.5 0.9 0.0 0.0 23.1 9.8 0.6 10.5 1.5 1.6 0.0 0.1 1.1 0.0 0.4 5.0 24.0 0.0 0.0 0.6 1.7 5.9 3.7 1.0 5.4 1.0 4.0 1.3 0.0 25.1 8.5 3.7 0.0 6.8 14.6 0.4 0.0 0.1 0.2 0.8 0.0 3.6 8.4 1.7 0.1 0.0 0.6 0.3 0.9 0.1 0.1 0.2 ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 133.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 81.7;Leydig cells: 425.9;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "ASC diff: 149.9;ASC TERT1: 60.1;HHSteC: 64.9;HSkMC: 147.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" NA NA 380000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" 56.6 45.1 2.0 10.5 2.7 0.9 26.9 2.3 2.7 21.3 1.5 56.7 9.6 69.2 14.0 33.8 59.0 27.9 22.8 2.9 1.9 17.5 23.9 12.6 3.5 2.1 1.5 68.2 21.9 1.1 2.1 133.8 1.4 12.3 27.5 9.6 36.3 9.5 30.3 9.0 26.7 65.5 2.2 10.9 21.6 15.6 1.7 8.6 41.1 57.3 6.9 23.9 17.1 2.3 0.2 0.0 4.0 0.0 149.9 60.1 0.0 0.1 0.0 0.4 0.8 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 64.9 0.0 0.1 147.5 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 2.7 2.3 2.7 2.9 1.9 2.1 1.5 1.4 2.2 1.7 2.3 16.5 0.0 0.0 9.4 1.3 3.7 0.0 0.0 1.2 2.3 0.8 0.5 3.7 41.5 0.0 1.8 6.2 0.6 0.1 0.0 1.9 2.4 1.4 3.3 40.3 4.1 0.0 0.0 14.8 0.4 0.4 81.7 1.1 5.5 0.0 1.6 8.9 1.0 1.4 0.0 14.9 0.0 0.0 0.0 4.6 10.6 425.9 0.8 3.6 8.4 0.0 31.6 0.0 21.6 0.7 0.0 5.0 212.1 0.4 0.1 0.1 0.1 0.7 10.9 39.5 10.0 51.8 0.8 0.6 0.2 3.7 1.4 0.5 2.7 0.0 0.1 ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.4;Endothelial cells: 34.6;Fibroblasts: 99.7;Oligodendrocyte precursor cells: 35.2;Skeletal myocytes: 39.3;Smooth muscle cells: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 140.4;ASC TERT1: 94.9;BJ hTERT+: 205.9;HSkMC: 98.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" 109.5 11.5 6.1 33.5 12.9 0.2 71.2 15.1 8.6 67.7 12.4 76.5 15.1 72.9 13.7 21.7 31.4 67.0 69.2 6.9 9.4 13.4 14.8 22.5 8.1 12.0 12.4 44.2 5.5 4.1 3.4 21.4 11.7 24.7 17.9 0.9 18.0 27.1 57.6 29.2 27.8 63.4 9.9 49.2 28.9 4.4 12.6 4.7 15.7 36.6 8.9 59.4 49.1 15.4 0.0 0.0 17.4 0.0 140.4 94.9 9.4 8.1 205.9 9.2 8.5 0.0 0.0 0.0 7.0 21.4 1.8 0.1 1.7 0.0 4.8 0.1 0.0 0.0 0.1 0.5 30.3 0.1 0.0 98.2 0.0 20.0 0.0 28.7 27.6 2.3 0.0 0.1 6.3 0.0 0.2 4.3 18.4 0.0 1.0 16.5 27.3 1.6 2.2 0.0 9.3 10.1 0.0 0.0 0.0 3.3 0.0 0.0 8.8 35.5 4.5 50.4 0.0 0.0 0.1 0.0 37.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 12.9 15.1 8.6 6.9 9.4 12.0 12.4 11.7 9.9 12.6 15.4 47.4 9.6 2.4 1.0 0.1 14.3 7.0 0.2 3.4 14.4 0.6 6.6 16.6 0.0 0.1 0.0 2.1 1.0 0.5 0.1 0.0 0.2 1.6 1.4 20.2 34.6 0.0 0.0 0.6 0.0 0.8 99.7 1.1 1.0 0.0 2.9 5.0 0.0 1.4 0.0 1.5 0.0 0.0 0.0 17.4 1.5 20.8 0.8 7.2 1.9 0.0 1.9 0.0 35.2 19.2 1.2 0.0 6.4 0.0 1.7 0.0 2.4 1.6 0.8 0.0 39.3 43.5 1.0 0.0 1.4 11.1 2.6 1.7 1.1 0.0 0.6 ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "ovary: 22.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 19.4;Langerhans cells: 11.3;Leydig cells: 27.7;Melanocytes: 7.2;Peritubular cells: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 2.7" "Region enhanced" "Detected in some" "spinal cord: 3.3" HPA038516 Uncertain "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038516: AB_10672749" "unprognostic (8.28e-3)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-1)" "unprognostic (4.88e-2)" "unprognostic (6.74e-4)" "unprognostic (1.96e-1)" "unprognostic (1.53e-8)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-3)" 4.3 0.2 0.1 0.0 0.2 0.0 5.5 0.2 0.4 0.2 0.4 0.3 0.1 0.0 4.4 0.2 0.3 0.2 2.7 0.2 0.2 0.0 0.0 0.9 0.1 0.2 0.1 22.4 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.4 0.2 0.4 2.4 0.2 0.0 0.2 0.0 0.1 1.6 0.1 0.0 0.7 1.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 2.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 2.1 0.9 0.6 0.8 0.0 0.0 2.7 0.0 0.1 19.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 11.3 0.8 27.7 0.1 7.2 4.7 0.0 0.2 0.0 1.0 0.2 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.2 1.0 0.2 0.2 0.0 5.5 0.1 0.5 5.7 0.0 0.0 ANGPTL7 "AngX, CDT6" ENSG00000171819 "Angiopoietin like 7" O43827 1 11189355-11195981 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Cardiomyocytes: 4.1;Enteroendocrine cells: 1.8;Fibroblasts: 6.9;Melanocytes: 3.6;Microglial cells: 1.9" "Cancer enriched" "Detected in some" 14 "melanoma: 18.4" "Region enhanced" "Detected in some" "thalamus: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 65 "SCLC-21H: 41.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 13 "spinal cord: 62.2" "Secreted in other tissues" NA NA 1100000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-2)" "unprognostic (6.95e-2)" "unprognostic (1.22e-1)" "unprognostic (2.67e-3)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.89e-2)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (1.58e-2)" "unprognostic (3.41e-3)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "unprognostic (2.49e-2)" 15.9 2.2 0.3 1.3 0.2 0.0 5.3 1.9 1.0 4.8 0.2 9.2 0.8 0.5 2.1 2.2 2.2 3.8 7.6 0.1 0.4 2.7 0.1 1.3 0.0 0.4 0.5 0.4 0.4 0.0 4.2 0.6 0.3 4.2 1.5 0.2 2.3 6.6 7.8 6.2 1.8 1.9 0.0 0.3 2.3 0.2 4.3 0.3 0.7 5.7 0.2 4.2 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.9 1.0 0.1 0.4 0.4 0.5 0.3 0.0 4.3 0.4 0.1 3.2 0.0 0.3 0.0 0.1 0.1 0.0 1.2 0.1 0.2 0.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.8 0.0 0.3 0.0 0.0 6.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.4;Fibroblasts: 31.2;Leydig cells: 36.4;Muller glia cells: 57.7;Peritubular cells: 50.8;Skeletal myocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.6;THP-1: 6.8;TIME: 8.4;U-87 MG: 8.3;U-937: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" 4.0 1.3 8.2 1.1 7.9 0.3 4.6 7.6 9.7 20.6 6.4 6.0 0.5 5.8 1.4 24.7 6.6 1.3 2.9 7.5 8.6 0.8 2.5 2.3 0.4 8.7 9.5 4.4 0.7 0.0 2.0 0.1 8.5 6.6 0.8 1.3 11.4 2.7 8.2 60.8 2.5 2.1 8.4 0.5 3.9 1.6 9.0 0.5 1.7 3.8 6.7 7.3 20.6 7.6 0.1 0.0 0.0 0.0 2.2 9.6 0.2 1.4 3.6 0.4 1.2 0.4 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 1.1 2.9 0.1 3.3 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.2 0.0 0.0 3.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.5 0.0 0.0 2.1 0.0 0.7 0.8 0.1 0.0 0.3 1.1 0.3 0.0 0.2 0.7 0.1 0.7 0.2 0.5 0.7 0.7 8.2 7.9 7.6 9.7 7.5 8.6 8.7 9.5 8.5 8.4 9.0 7.6 1.6 0.0 0.0 6.8 0.3 4.6 16.8 10.2 0.0 1.1 6.3 13.5 1.5 2.8 9.5 1.8 0.0 0.1 2.2 0.0 0.0 0.0 3.5 56.4 10.9 1.3 0.0 2.7 5.6 0.4 0.1 31.2 0.5 17.2 19.1 0.0 2.2 13.9 11.0 0.0 2.1 0.0 14.2 1.2 4.6 5.9 36.4 1.1 5.4 1.0 1.1 57.7 5.2 3.0 0.6 0.1 0.0 50.8 0.4 5.3 0.0 0.1 9.8 2.7 0.0 29.5 6.4 0.1 1.0 10.4 12.4 0.3 5.5 1.1 0.0 13.6 ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 215.4;HHSteC: 197.9;LHCN-M2: 221.0;U-2197: 176.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 13000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.01e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-2)" "unprognostic (4.87e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-2)" "unprognostic (6.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.34e-6)" "unprognostic (1.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" 60.9 30.0 4.1 35.4 4.1 18.7 18.7 3.6 6.4 52.2 5.0 39.9 23.0 95.4 21.9 24.5 31.2 54.9 31.8 3.6 5.0 17.1 34.4 24.7 16.2 4.7 5.0 75.0 4.6 27.8 1.6 90.0 4.2 110.2 42.7 1.6 10.1 90.3 6.1 6.1 29.6 108.3 5.5 18.3 23.2 8.4 4.0 10.7 4.9 21.7 16.1 53.1 12.0 4.4 15.5 1.9 34.6 6.6 215.4 118.0 3.1 48.3 124.6 17.5 19.9 0.6 11.8 0.0 0.8 76.8 11.4 4.5 4.4 49.7 66.9 2.2 4.2 12.2 1.3 4.8 197.9 51.6 29.5 145.3 15.2 132.7 68.3 150.2 52.6 1.6 27.1 35.8 221.0 0.0 1.1 57.1 5.7 21.7 70.3 2.4 19.8 9.0 12.0 14.4 30.6 41.2 4.9 0.6 8.2 16.3 0.7 11.0 69.8 155.7 9.7 176.7 103.4 3.1 0.0 0.1 78.6 39.4 49.0 72.7 17.5 61.6 12.8 9.5 13.8 23.5 21.4 13.1 32.2 9.4 11.3 5.9 54.4 4.3 18.0 32.2 40.4 14.0 4.1 4.1 3.6 6.4 3.6 5.0 4.7 5.0 4.2 5.5 4.0 4.4 6.4 12.8 10.0 23.5 25.7 7.0 15.5 6.5 4.0 6.9 4.0 2.2 24.9 4.3 10.2 0.0 29.2 18.3 24.9 42.4 3.9 4.2 2.3 7.7 69.3 15.5 18.6 6.3 25.4 6.7 29.0 58.7 4.1 6.1 60.1 8.9 15.0 24.9 17.7 0.0 2.1 15.1 4.1 13.4 28.9 5.3 39.1 28.3 1.8 45.9 53.7 6.9 4.1 19.1 0.8 45.5 28.9 63.9 14.1 13.9 16.9 2.5 4.9 21.4 39.5 32.5 28.5 0.6 2.1 0.9 4.3 6.6 24.4 18.3 13.3 1.6 APCDD1L FLJ90166 ENSG00000198768 "APC down-regulated 1 like" Q8NCL9 20 58459101-58515399 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 19.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.1;Breast myoepithelial cells: 7.7;Fibroblasts: 3.6;Oligodendrocyte precursor cells: 6.0;Skeletal myocytes: 8.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 94.5;hTEC/SVTERT24-B: 32.7;HUVEC TERT2: 33.6;TIME: 56.1;U-87 MG: 36.5" "Not detected" "Not detected" HPA067015 Uncertain Uncertain Mitochondria No No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA067015: AB_2685764" "unprognostic (2.61e-1)" "unprognostic (8.26e-3)" "unprognostic (4.63e-3)" "unprognostic (1.35e-5)" "unprognostic (4.09e-3)" "unprognostic (9.73e-3)" "unprognostic (1.31e-3)" "unprognostic (1.06e-4)" "unprognostic (7.63e-4)" "unprognostic (2.14e-2)" "unprognostic (7.62e-3)" "unprognostic (2.16e-1)" "unprognostic (6.55e-13)" "unprognostic (5.01e-3)" "unprognostic (3.21e-1)" "unprognostic (2.24e-2)" "unprognostic (1.81e-3)" 0.4 0.4 0.2 0.2 0.0 0.0 4.8 0.5 0.1 1.7 0.0 1.0 0.1 1.8 0.0 0.5 0.0 0.7 1.4 0.1 0.0 2.9 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.0 0.5 0.6 0.0 19.2 1.3 0.6 0.8 0.4 0.6 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 4.4 0.6 0.0 0.0 0.0 0.0 0.0 0.4 3.1 0.0 16.8 0.1 1.9 1.4 0.0 5.6 0.0 0.0 94.5 0.5 1.1 0.0 3.3 3.3 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.6 0.0 32.7 0.5 6.8 33.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 56.1 12.6 0.9 0.0 16.5 0.0 0.0 0.0 36.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.1 0.0 0.3 0.4 0.0 0.0 9.1 7.7 0.9 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.7 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 6.0 0.5 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 8.4 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4485.3;Leydig cells: 2077.4;Melanocytes: 1028.1;Peritubular cells: 994.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 6 "ASC diff: 3507.4;ASC TERT1: 1918.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" 2071.8 84.8 949.6 13.9 1157.3 0.9 5037.8 1174.9 1364.1 620.2 1370.1 144.7 56.0 496.7 155.7 160.0 750.6 213.3 1007.8 952.8 1010.4 49.7 7.1 183.5 24.6 1148.3 1040.5 131.2 212.4 61.9 192.2 350.5 1122.0 419.8 57.2 0.8 1272.3 183.8 1154.9 970.1 88.4 96.2 1027.5 8.2 402.6 75.7 1070.2 113.5 828.8 625.3 20.8 434.4 591.7 1347.6 0.0 2.2 0.5 0.7 3507.4 1918.1 6.1 31.3 7.6 0.1 0.2 222.4 0.4 0.4 0.9 1.8 0.0 0.9 0.4 10.5 0.3 0.3 2.4 0.3 0.2 0.1 12.5 0.3 0.5 91.4 21.0 0.2 17.0 0.3 4.3 0.2 0.2 0.9 5.3 1.3 0.1 0.7 0.5 38.9 0.5 0.1 0.0 0.6 0.0 2.8 0.7 0.5 0.0 34.8 31.8 1.3 67.2 0.1 0.4 0.5 1.4 0.4 0.1 0.2 0.3 9.2 1.0 0.4 420.3 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 949.6 1157.3 1174.9 1364.1 952.8 1010.4 1148.3 1040.5 1122.0 1027.5 1070.2 1347.6 543.2 0.0 11.0 2.9 7.5 145.0 16.0 25.4 46.7 0.0 121.6 138.7 26.9 1.5 81.8 5.5 0.0 5.4 15.9 1.4 0.0 0.4 9.7 16.3 393.7 114.1 46.3 0.0 3.3 0.0 4.2 4485.3 7.7 7.0 0.0 0.0 21.4 0.0 13.3 0.0 2.1 0.7 10.2 0.3 193.2 51.0 2077.4 31.8 1028.1 279.2 1.0 0.0 0.0 300.6 221.5 2.3 0.3 994.5 19.2 25.7 0.0 0.2 128.9 0.0 19.7 100.3 210.7 10.5 4.0 24.1 102.6 5.9 23.5 7.0 0.6 47.3 ARHGEF10 "Gef10, KIAA0294" ENSG00000104728 "Rho guanine nucleotide exchange factor 10" O15013 8 1823926-1958641 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 158.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024649 Approved Approved Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA024649: AB_1845002" "unprognostic (2.51e-1)" "unprognostic (3.60e-2)" "unprognostic (2.39e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (7.27e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-2)" "unprognostic (9.29e-2)" "unprognostic (3.37e-2)" "unprognostic (1.81e-2)" "unprognostic (4.42e-1)" "unprognostic (3.18e-2)" "unprognostic (4.46e-2)" 19.2 10.1 9.3 2.3 9.9 0.4 15.2 9.3 9.6 14.7 9.3 19.1 0.5 18.7 2.7 5.5 15.0 1.9 18.3 9.0 8.9 12.4 3.4 27.9 1.6 9.7 9.8 13.5 6.6 1.1 7.3 3.0 10.3 12.8 1.6 1.9 12.1 3.1 4.0 13.3 9.3 4.7 8.8 6.9 14.2 24.3 9.1 2.1 12.9 1.1 1.1 12.3 13.4 11.7 7.1 7.6 7.7 4.0 6.8 7.4 1.9 9.4 6.9 6.5 7.8 2.5 3.2 0.0 1.0 11.7 11.1 5.3 8.4 10.9 8.8 0.0 3.0 3.2 8.6 0.0 6.0 0.0 2.1 6.5 6.2 7.7 6.1 10.0 11.8 2.5 3.1 0.0 8.0 3.8 5.8 1.1 6.6 5.3 4.2 0.3 8.6 0.0 6.2 2.7 1.5 1.6 5.7 0.2 5.3 9.4 3.1 2.1 13.2 5.9 3.8 0.1 8.4 0.0 2.9 0.1 6.0 8.4 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.3 9.9 9.3 9.6 9.0 8.9 9.7 9.8 10.3 8.8 9.1 11.7 11.7 3.2 4.1 90.1 0.9 38.4 13.4 8.1 5.7 7.7 7.8 6.3 13.3 15.7 5.0 7.3 10.4 0.6 2.6 1.4 0.0 7.5 17.8 3.3 11.4 27.7 1.2 3.6 17.3 2.0 1.6 30.0 4.1 6.9 0.0 11.3 13.9 1.2 1.7 21.9 16.3 4.5 8.2 1.6 9.4 20.5 35.1 2.1 23.2 50.6 0.3 10.1 4.1 69.9 158.9 12.4 0.3 26.4 2.3 22.6 0.7 0.8 2.8 9.2 0.0 22.6 14.2 54.9 38.3 1.4 15.2 0.3 2.1 7.7 2.4 6.3 AS3MT CYT19 ENSG00000214435 "Arsenite methyltransferase" Q9HBK9 10 102869470-102901899 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 302.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Basal squamous epithelial cells: 1.2;Proximal tubular cells: 1.0" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.8;REH: 54.6;SH-SY5Y: 27.8;T-47d: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017856 Enhanced Approved Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA017856: AB_1847420" "unprognostic (1.11e-1)" "unprognostic (2.02e-4)" "unprognostic (2.45e-1)" "unprognostic (2.25e-1)" "unprognostic (3.39e-1)" "unprognostic (1.66e-1)" "unprognostic (7.02e-4)" "unprognostic (3.22e-1)" "unprognostic (1.42e-1)" "unprognostic (3.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-10)" "unprognostic (1.04e-2)" "unprognostic (4.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" 5.1 302.4 7.4 1.3 7.5 0.7 6.3 11.5 8.7 7.5 9.3 6.4 3.0 7.7 4.4 3.6 5.8 6.7 26.8 6.7 8.4 19.2 59.2 4.0 2.0 7.9 8.3 8.7 11.7 65.7 6.6 1.0 8.0 9.1 1.8 4.8 4.8 5.2 11.4 4.3 3.3 3.9 6.6 18.3 4.7 8.7 7.7 3.7 7.7 15.2 1.6 3.2 5.0 8.3 0.0 7.6 26.8 17.4 0.6 0.6 5.1 8.1 6.7 11.9 14.3 21.3 1.2 0.0 2.4 10.7 0.6 0.4 23.8 1.4 12.4 0.3 6.7 0.0 3.2 20.9 7.7 0.2 0.6 3.7 3.1 1.6 0.0 21.3 0.5 25.3 0.0 0.4 10.8 0.1 4.9 0.7 13.2 0.1 1.0 54.6 0.0 0.2 2.7 0.0 0.4 27.8 0.0 0.4 3.7 8.8 43.9 0.6 0.1 2.6 0.0 3.9 0.0 0.2 0.4 0.0 8.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.4 7.5 11.5 8.7 6.7 8.4 7.9 8.3 8.0 6.6 7.7 8.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.2;Fibroblasts: 94.6;Microglial cells: 24.4;Sertoli cells: 39.5;Smooth muscle cells: 73.5;Suprabasal keratinocytes: 27.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 16.0;BJ hTERT+: 5.7;HHSteC: 23.2;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" 29.6 7.6 1.2 5.7 1.7 0.1 11.8 2.3 2.0 40.9 0.9 25.5 9.6 69.6 9.7 10.1 16.9 65.9 95.3 1.2 1.2 11.2 41.1 14.3 3.0 1.3 1.2 7.1 13.4 3.8 2.5 4.3 1.6 4.7 11.3 0.2 3.2 11.7 7.8 12.1 17.6 110.5 1.0 2.3 12.0 1.2 1.8 2.5 11.1 19.8 5.5 13.4 5.0 1.7 0.1 0.0 0.0 0.0 1.4 16.0 0.2 2.6 5.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 23.2 0.2 0.0 4.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 1.2 1.7 2.3 2.0 1.2 1.2 1.3 1.2 1.6 1.0 1.8 1.7 12.9 0.0 1.1 0.3 0.1 67.2 0.1 0.0 0.0 0.4 0.4 0.1 8.5 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 4.2 6.8 0.0 0.0 2.0 0.0 0.1 94.6 0.5 0.2 1.3 0.1 13.9 0.4 0.2 0.0 1.7 0.0 0.0 0.0 13.5 0.6 5.9 0.8 14.2 24.4 0.0 0.1 0.0 1.5 1.1 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.7 0.6 39.5 4.3 73.5 0.0 0.1 0.3 27.0 0.0 1.7 0.3 0.0 0.0 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677271-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enriched" "Detected in many" 6 "Microglial cells: 216.4" "Cancer enhanced" "Detected in all" "melanoma: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 23.0;fHDF/TERT166: 22.9;HMC-1: 19.4;SK-MEL-30: 21.9;U-2197: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 6.5 8.7 13.7 2.7 9.3 2.5 5.3 6.0 8.9 2.0 0.7 3.2 0.8 1.5 0.1 1.9 2.3 3.7 2.0 5.9 5.8 5.8 0.6 7.1 1.8 9.9 9.7 1.1 1.4 3.5 2.1 1.7 9.5 2.2 0.8 0.1 7.9 0.6 0.6 2.5 3.0 2.8 5.9 1.5 3.2 4.3 15.0 1.1 2.5 0.7 1.1 2.5 1.4 4.9 0.0 5.7 1.3 0.0 2.2 2.8 0.0 23.0 9.3 6.1 9.9 0.0 0.0 0.0 1.6 22.9 0.0 0.0 9.3 1.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.0 19.4 0.9 0.0 0.6 0.0 2.5 0.0 1.2 0.0 0.0 3.3 0.0 1.2 0.0 1.5 0.0 1.5 4.4 4.6 2.8 9.9 0.0 0.0 0.1 0.0 0.0 21.9 0.0 7.4 1.2 0.0 8.9 0.2 12.7 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.3 0.5 0.1 0.0 0.7 0.6 0.0 1.2 0.0 1.0 0.1 0.3 13.7 9.3 6.0 8.9 5.9 5.8 9.9 9.7 9.5 5.9 15.0 4.9 0.3 32.1 8.6 2.0 0.8 1.0 0.0 2.7 0.6 0.2 2.6 1.8 1.7 1.5 5.3 0.0 0.0 0.0 11.1 0.1 0.0 0.5 23.2 2.8 2.8 4.2 0.0 0.0 4.5 0.0 0.1 5.0 3.1 7.9 15.2 0.0 0.4 0.1 2.5 0.0 2.1 0.2 0.0 2.5 5.2 21.8 4.1 4.5 17.8 216.4 2.3 0.0 14.4 1.5 2.7 0.8 0.0 17.7 1.7 0.7 0.0 0.1 4.2 0.1 0.0 4.7 9.1 0.4 1.2 0.0 0.4 0.0 8.6 0.1 0.0 0.0 AVIL "ADVIL, DOC6, FLJ12386, p92" ENSG00000135407 Advillin O75366 12 57797376-57818704 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 9.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 28.3;Gastric mucus-secreting cells: 23.9" "Cancer enriched" "Detected in all" 5 "glioma: 9.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.0" "Cell line enhanced" "Detected in some" "Daudi: 4.6;RH-30: 8.5;U-266/84: 3.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA058864 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "HPA058864: AB_2683838" "unprognostic (3.86e-2)" "unprognostic (9.86e-3)" "unprognostic (4.36e-2)" "unprognostic (3.38e-3)" "unprognostic (1.36e-1)" "unprognostic (7.79e-4)" "unprognostic (1.42e-1)" "unprognostic (7.44e-2)" "unprognostic (9.13e-2)" "unprognostic (8.02e-2)" "unprognostic (1.04e-2)" "unprognostic (1.07e-2)" "unprognostic (2.57e-4)" "unprognostic (2.44e-1)" "unprognostic (9.41e-2)" "unprognostic (3.29e-1)" "prognostic favorable (2.71e-4)" 1.3 3.5 2.0 1.5 3.6 0.7 1.3 7.6 2.5 1.3 2.6 2.8 3.0 1.0 3.2 0.6 1.3 1.9 1.5 2.2 1.7 1.6 1.7 1.5 0.7 2.2 1.8 1.6 3.8 0.3 1.8 1.4 2.0 1.5 1.6 4.9 1.7 1.2 9.3 5.6 3.4 1.2 1.0 1.3 1.1 0.8 2.3 1.0 2.9 1.5 0.8 1.2 1.0 1.4 0.3 0.4 2.9 2.0 0.7 1.3 0.2 0.2 0.1 0.0 0.2 0.0 1.0 4.6 0.4 0.4 0.0 1.6 0.1 0.0 0.3 0.0 1.4 0.5 1.3 0.9 0.3 1.9 0.0 0.9 0.7 0.1 0.4 0.1 0.4 0.4 0.3 1.9 0.0 0.4 0.0 2.0 0.2 0.0 1.0 0.1 8.5 0.3 0.2 0.9 0.6 0.0 0.4 0.3 1.0 0.6 0.6 0.0 0.2 1.2 0.1 0.9 0.0 0.9 3.5 0.5 0.5 0.3 0.3 0.2 0.8 1.4 0.6 0.4 0.7 0.6 1.1 0.5 0.3 1.1 1.0 0.8 5.0 0.4 0.5 0.8 0.3 0.0 2.0 3.6 7.6 2.5 2.2 1.7 2.2 1.8 2.0 1.0 2.3 1.4 5.3 3.2 7.7 15.0 3.4 2.9 3.7 3.6 4.0 28.3 8.8 7.4 1.2 5.7 4.6 3.7 18.8 1.3 1.3 11.9 0.0 4.7 6.0 6.1 5.4 5.0 7.7 2.7 13.4 6.0 1.0 5.4 23.9 11.1 1.3 2.0 12.8 2.8 2.2 8.4 8.5 3.4 10.2 3.3 3.1 2.8 4.1 2.6 3.6 5.6 3.4 11.3 5.2 5.5 7.0 4.5 3.7 0.7 1.3 4.9 2.9 1.1 3.2 21.6 6.6 8.8 4.1 1.4 2.7 2.5 4.1 2.9 2.7 5.8 4.1 2.7 AZI2 "AZ2, FLJ21939, NAP1" ENSG00000163512 "5-azacytidine induced 2" Q9H6S1 3 28315003-28349050 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035258 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "HPA035258: AB_10602329" "unprognostic (1.86e-2)" "unprognostic (2.17e-2)" "unprognostic (2.11e-3)" "unprognostic (1.05e-1)" "unprognostic (2.38e-1)" "unprognostic (3.60e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (3.76e-2)" "unprognostic (1.44e-1)" "unprognostic (7.48e-3)" "unprognostic (2.72e-1)" "unprognostic (1.17e-1)" "unprognostic (3.30e-3)" "unprognostic (1.66e-1)" "unprognostic (3.34e-1)" "unprognostic (2.92e-3)" "prognostic unfavorable (2.77e-4)" 27.1 11.6 17.1 9.1 17.4 20.8 12.7 17.5 19.8 12.5 18.4 10.4 12.0 12.0 10.7 9.7 10.6 13.1 14.7 16.2 19.0 14.9 11.3 12.5 9.9 17.1 17.2 13.1 11.2 12.8 13.9 12.3 17.6 12.4 9.8 13.6 17.8 10.5 14.1 9.8 11.3 11.8 16.3 10.0 10.9 16.5 18.8 14.0 14.0 12.0 8.6 11.7 8.6 17.8 20.5 20.6 27.4 16.4 43.0 69.0 40.3 25.5 52.6 44.3 52.7 18.3 20.2 12.6 15.5 36.0 29.7 8.4 21.2 42.4 35.9 34.2 23.7 23.8 20.6 25.4 64.4 24.6 14.5 69.9 57.1 35.7 61.9 28.9 24.6 26.6 36.0 22.9 41.1 19.4 31.3 19.4 19.1 13.5 30.0 14.6 29.5 13.0 19.3 11.5 14.6 35.8 22.3 25.6 52.3 24.7 17.7 25.6 17.0 29.4 24.2 24.9 31.3 26.5 27.6 18.3 31.1 51.4 27.2 74.7 37.8 26.3 13.3 31.2 16.1 6.3 12.6 15.5 16.7 8.4 12.0 11.0 10.4 11.0 28.1 13.5 18.9 19.1 17.1 17.4 17.5 19.8 16.2 19.0 17.1 17.2 17.6 16.3 18.8 17.8 31.6 64.1 49.5 21.9 17.0 24.9 34.4 53.6 34.7 29.3 33.0 28.6 23.1 24.3 46.9 23.9 37.5 32.4 34.9 33.1 45.0 26.4 26.9 49.0 46.8 28.1 26.9 31.8 28.2 28.2 57.0 55.6 16.8 30.2 19.6 27.5 32.9 38.3 33.7 15.2 43.6 29.0 38.7 63.0 11.0 28.1 46.9 57.6 8.8 16.9 61.8 30.5 22.6 32.6 32.6 30.5 28.8 41.0 32.8 28.8 34.8 50.0 57.9 30.9 46.0 44.4 34.6 68.0 61.3 32.0 34.7 62.7 28.7 32.0 24.5 28.3 BBS10 "C12orf58, FLJ23560" ENSG00000179941 "Bardet-Biedl syndrome 10" Q8TAM1 12 76344474-76348415 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Chaperone "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058743 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "HPA058743: AB_2683806" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (4.48e-3)" "unprognostic (3.14e-2)" "unprognostic (1.57e-2)" "unprognostic (2.22e-2)" "unprognostic (4.12e-2)" "unprognostic (6.86e-2)" "unprognostic (5.82e-2)" "unprognostic (7.35e-2)" "unprognostic (6.77e-2)" "unprognostic (3.49e-2)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (2.74e-1)" 11.6 12.0 7.3 6.0 7.9 0.9 11.8 8.8 10.8 7.6 6.5 4.2 3.9 8.2 9.8 6.6 7.6 5.5 10.3 7.0 7.1 9.8 9.1 6.0 9.0 7.7 7.2 12.6 4.4 7.6 4.3 7.6 8.3 8.2 3.9 11.4 9.8 7.9 5.5 7.3 4.4 6.1 8.4 9.2 5.1 6.2 7.0 8.9 9.3 7.8 7.7 5.4 4.8 10.3 10.9 6.9 14.2 7.4 19.9 21.0 6.0 11.9 8.6 10.0 7.5 5.7 5.1 5.2 11.9 6.4 8.8 11.6 9.7 10.2 14.0 9.0 10.3 7.1 7.7 8.1 25.2 7.6 5.4 13.8 14.5 13.3 16.1 26.8 14.0 15.0 8.9 4.0 19.4 6.9 7.7 8.2 8.8 5.3 9.6 7.9 17.6 8.4 9.9 5.6 8.7 16.4 15.5 3.0 11.1 13.6 16.2 8.1 10.9 12.3 7.2 12.5 7.8 8.4 11.3 4.6 8.9 6.1 9.4 2.6 2.1 5.0 0.5 4.0 1.2 1.6 1.0 0.8 2.5 1.2 2.2 1.4 1.8 0.7 7.2 1.6 0.9 1.2 7.3 7.9 8.8 10.8 7.0 7.1 7.7 7.2 8.3 8.4 7.0 10.3 4.0 3.2 3.6 5.9 3.7 4.0 3.7 3.5 5.2 4.4 3.4 3.2 8.8 1.5 5.1 3.7 0.0 3.7 3.8 0.4 3.9 3.1 0.1 2.8 7.3 4.0 3.0 4.0 5.4 2.5 1.0 6.2 2.0 1.8 0.0 4.1 4.6 8.7 3.0 1.7 5.2 1.6 2.0 7.3 2.1 0.6 8.7 3.4 0.0 6.5 2.4 8.7 1.0 4.5 9.9 3.2 1.7 11.3 0.3 2.2 1.5 8.4 6.7 4.3 6.6 6.5 3.9 8.7 6.5 4.9 4.1 0.8 2.1 2.1 1.6 1.7 BCL6 "BCL5, BCL6A, LAZ3, ZBTB27, ZNF51" ENSG00000113916 "BCL6 transcription repressor" P41182 3 187721377-187745725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Immunity, Inflammatory response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 485.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 205.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "neutrophil: 269.1;non-classical monocyte: 76.4" "Group enriched" "Detected in all" 7 "granulocytes: 269.1;monocytes: 76.4" "Cell line enhanced" "Detected in many" "Daudi: 166.4;HSkMC: 113.9;U-698: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000307, HPA004899, HPA050645" Enhanced Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB000307: AB_2063451, HPA004899: AB_1078273, HPA050645: AB_2681199" "unprognostic (5.36e-2)" "unprognostic (3.29e-2)" "unprognostic (1.63e-3)" "unprognostic (2.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.34e-3)" "unprognostic (2.62e-2)" "unprognostic (3.33e-3)" "unprognostic (8.75e-2)" "unprognostic (2.04e-2)" "unprognostic (1.63e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.27e-9)" "unprognostic (5.22e-2)" "unprognostic (7.82e-2)" "unprognostic (5.67e-2)" "unprognostic (2.58e-2)" 143.0 49.4 54.3 53.9 53.4 123.7 126.9 85.9 57.9 100.0 35.0 87.1 7.5 68.1 16.4 44.6 140.7 45.6 72.1 50.9 68.7 37.0 65.3 110.5 56.0 104.1 69.4 65.6 49.2 11.3 44.8 15.3 74.2 57.5 10.3 34.2 70.3 22.2 485.9 160.7 34.4 43.0 55.9 106.3 58.4 18.6 69.0 43.2 50.4 96.6 47.7 90.6 81.5 64.1 5.1 13.8 14.4 3.2 98.1 78.0 14.9 16.5 39.2 18.4 19.4 9.4 7.6 166.4 11.5 21.0 11.7 7.7 4.4 10.6 15.3 33.8 5.1 0.2 6.7 22.5 51.5 2.1 0.9 113.9 68.8 22.7 32.9 60.1 10.2 4.2 1.6 27.6 18.2 5.7 5.5 1.3 1.4 3.0 10.3 45.4 7.0 0.8 13.6 23.2 3.1 0.2 18.8 8.1 11.0 30.2 35.3 5.9 21.2 43.7 7.1 16.6 7.5 21.2 7.2 231.6 24.2 6.0 31.7 8.8 33.0 18.9 5.5 37.3 5.4 6.6 3.4 5.0 24.6 15.3 2.1 2.3 269.1 3.9 76.4 4.0 3.1 30.7 54.3 53.4 85.9 57.9 50.9 68.7 104.1 69.4 74.2 55.9 69.0 64.1 35.7 19.2 67.4 66.0 22.7 47.3 14.7 18.8 205.5 10.9 55.3 54.6 71.4 14.3 28.9 16.5 20.9 1.4 36.0 3.5 0.0 12.2 13.3 36.2 26.7 25.0 4.8 3.2 7.6 12.5 2.7 57.3 12.2 51.4 11.4 9.4 15.0 51.2 11.9 0.0 19.6 2.3 16.2 67.5 74.4 8.6 28.9 48.1 35.6 7.5 16.8 39.1 1.0 50.8 7.8 7.9 0.3 18.8 14.2 27.9 1.2 1.5 29.5 9.7 32.9 77.0 84.9 0.4 1.2 72.4 61.5 4.1 30.0 10.3 2.8 29.7 BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.3;Endothelial cells: 18.2;Fibroblasts: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 49.2;BJ hTERT+: 94.5;U-87 MG: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" 14.0 1.4 0.8 5.5 1.0 0.0 5.8 3.8 1.1 15.6 0.9 12.4 7.9 6.7 2.4 17.2 7.2 20.8 1.2 0.9 0.8 13.4 0.7 2.5 0.3 4.9 1.3 1.0 9.4 0.9 0.8 1.3 5.0 4.8 12.2 0.0 3.5 6.2 0.9 5.4 9.7 10.2 1.0 0.1 4.9 0.2 1.5 0.9 3.6 1.8 1.7 41.1 15.4 1.2 1.7 6.1 0.1 11.0 16.2 49.2 0.0 5.5 94.5 3.2 3.7 0.3 10.4 0.0 0.2 8.7 3.7 14.8 0.0 2.4 2.8 1.2 0.1 0.0 1.1 0.0 7.8 0.0 0.0 15.1 7.5 9.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.1 20.4 0.0 0.0 2.2 0.0 3.2 0.0 3.4 1.1 1.8 15.6 0.1 2.1 1.0 0.0 0.0 0.3 0.3 3.3 0.1 0.2 0.0 0.0 39.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.0 3.8 1.1 0.9 0.8 4.9 1.3 5.0 1.0 1.5 1.2 8.2 3.2 3.1 0.0 0.0 9.2 0.7 5.3 6.8 0.0 0.2 0.5 0.6 10.0 11.6 9.2 0.0 1.2 0.0 19.3 7.9 11.5 0.0 7.5 16.1 18.2 7.1 0.0 1.8 3.8 3.6 25.8 1.1 4.6 0.0 0.0 3.3 0.2 0.2 0.0 0.4 7.2 8.2 0.0 15.2 0.0 0.9 0.4 5.4 0.0 0.0 0.0 0.0 1.0 1.9 6.9 6.2 1.2 0.0 1.0 10.6 0.2 12.5 0.0 0.0 4.5 1.2 0.0 0.0 15.3 5.8 4.0 0.3 0.1 0.9 2.9 BICC1 ENSG00000122870 "BicC family RNA binding protein 1" Q9H694 10 58512872-58831435 "Disease related genes, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 120.5;Cholangiocytes: 158.7;Collecting duct cells: 86.5;Ductal cells: 98.5;Fibroblasts: 79.6;Microglial cells: 165.8;Proximal tubular cells: 148.2" "Group enriched" "Detected in all" 4 "pancreatic cancer: 9.2;renal cancer: 25.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 6.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "A549: 59.1;BJ hTERT+: 61.4;CACO-2: 93.1;RPTEC TERT1: 140.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070797 Approved Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol Centrosome "HPA070797: " "unprognostic (1.27e-1)" "unprognostic (1.57e-3)" "unprognostic (3.61e-1)" "unprognostic (1.96e-1)" "unprognostic (6.09e-3)" "unprognostic (1.72e-1)" "unprognostic (9.98e-3)" "unprognostic (1.79e-2)" "unprognostic (6.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.40e-3)" "unprognostic (7.16e-2)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" "unprognostic (4.19e-2)" "unprognostic (6.23e-2)" "unprognostic (2.94e-2)" 10.6 6.1 0.3 4.0 0.5 0.3 8.7 0.0 1.6 5.8 1.9 4.5 1.2 4.9 4.0 3.5 7.5 11.6 10.5 0.6 1.0 28.6 2.4 5.8 2.4 1.2 0.6 13.9 16.9 0.8 3.6 3.6 0.2 3.8 4.1 1.4 4.3 4.2 7.6 6.1 2.7 4.7 1.2 2.9 2.7 3.1 0.7 1.4 4.6 6.2 2.7 5.5 5.6 0.7 0.0 59.1 0.8 0.0 17.9 23.0 0.0 38.5 61.4 34.4 40.4 93.1 12.3 0.0 39.8 39.3 8.8 0.8 6.1 7.0 47.4 0.1 5.9 0.0 7.4 0.1 11.5 0.0 0.0 36.0 2.2 26.9 28.6 42.3 0.1 0.0 0.0 0.2 13.4 0.1 0.0 0.0 0.5 0.0 3.8 0.0 14.3 0.0 140.8 7.1 0.2 7.3 0.1 0.4 3.4 2.4 0.0 0.6 0.0 8.2 7.7 1.4 5.0 0.0 0.0 0.1 23.8 0.0 7.8 6.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.5 0.1 0.0 0.3 0.5 0.0 1.6 0.6 1.0 1.2 0.6 0.2 1.2 0.7 0.7 4.1 0.0 0.5 120.5 1.5 7.1 1.3 1.3 0.6 0.6 1.1 4.3 3.3 158.7 1.7 86.5 0.0 0.4 0.1 0.3 78.2 98.5 5.2 43.8 14.4 1.4 3.6 0.0 70.4 3.5 0.2 79.6 0.5 7.2 0.0 4.2 3.3 1.4 3.5 0.0 37.2 1.2 0.0 0.6 18.5 3.2 71.1 1.7 21.4 165.8 1.1 10.1 0.0 25.6 2.7 35.3 1.2 50.0 0.3 2.4 0.0 148.2 14.1 0.2 6.6 40.0 9.8 0.1 3.9 0.3 4.7 4.1 1.5 8.7 1.6 0.1 BLID BRCC2 ENSG00000259571 "BH3-like motif containing, cell death inducer" Q8IZY5 11 122115340-122116215 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "brain: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.9;hTEC/SVTERT24-B: 1.0;hTERT-RPE1: 1.0;LHCN-M2: 1.4;U-87 MG: 1.7" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" 0.0 0.0 1.1 0.0 3.4 0.0 0.0 1.6 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 2.5 0.0 0.0 0.0 0.0 3.8 1.9 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.1 0.0 0.3 0.2 0.3 0.0 0.9 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.9 1.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.4 1.6 1.7 1.2 2.5 3.8 1.9 3.0 1.7 3.0 5.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 BMERB1 "C16orf45, FLJ32618" ENSG00000166780 "BMERB domain containing 1" Q96MC5 16 15434475-15625028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 57.0" "Cancer enhanced" "Detected in all" "glioma: 30.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 8.7" "Lineage enriched" "Detected in many" 4 "T-cells: 8.7" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 101.8;U-2197: 81.3;U-87 MG: 124.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041114, HPA063757" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA041114: AB_10794542, HPA063757: " "unprognostic (1.02e-1)" "unprognostic (2.22e-1)" "unprognostic (1.67e-2)" "unprognostic (6.96e-2)" "unprognostic (3.79e-2)" "unprognostic (1.21e-1)" "prognostic favorable (1.53e-4)" "unprognostic (3.23e-2)" "unprognostic (1.90e-2)" "unprognostic (1.16e-2)" "unprognostic (3.64e-2)" "unprognostic (5.28e-2)" "prognostic favorable (1.75e-4)" "unprognostic (3.79e-3)" "unprognostic (8.31e-2)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" 30.9 15.4 90.3 10.5 111.6 1.1 21.6 67.4 112.7 46.0 48.2 46.1 8.3 40.5 19.7 21.4 38.4 23.9 47.3 107.0 87.2 23.1 21.8 13.4 6.4 123.0 74.0 40.9 18.6 3.9 40.8 1.3 118.5 32.4 9.3 40.6 12.6 27.6 86.9 13.0 19.1 35.6 69.6 9.2 21.6 40.3 80.5 4.0 13.5 41.3 4.0 44.4 25.3 96.2 1.4 31.5 12.8 1.5 56.7 50.7 0.3 18.1 62.6 15.5 8.4 0.0 0.9 0.1 4.0 101.8 37.5 0.2 4.1 5.3 7.9 0.4 0.7 6.7 11.9 1.5 19.4 0.1 13.6 24.5 5.2 33.8 0.5 25.8 25.2 14.5 0.4 0.5 24.2 21.6 5.1 0.9 17.2 0.4 10.7 1.0 16.3 0.1 8.8 4.6 26.2 27.6 0.9 8.3 5.5 2.1 0.4 0.4 8.9 34.2 17.6 81.3 9.4 5.7 12.5 0.2 124.3 0.2 7.1 0.1 0.1 0.1 8.7 0.0 1.7 2.1 2.0 5.2 0.5 1.3 1.5 2.8 0.6 0.2 0.1 0.2 2.6 1.1 90.3 111.6 67.4 112.7 107.0 87.2 123.0 74.0 118.5 69.6 80.5 96.2 7.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BNC2 "BSN2, FLJ20043" ENSG00000173068 "Basonuclin 2" Q6ZN30 9 16409503-16870843 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 26.9;ovary: 31.7;smooth muscle: 31.7" "Cell type enhanced" "Detected in many" "Astrocytes: 46.7;Leydig cells: 90.1;Microglial cells: 230.5;Peritubular cells: 67.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "gdT-cell: 2.5" "Lineage enriched" "Detected in single" 5 "T-cells: 2.5" "Cell line enhanced" "Detected in many" "HSkMC: 31.9;Karpas-707: 40.4;RPMI-8226: 28.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA018525, HPA059419" Approved Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA018525: AB_1845402, HPA059419: AB_2732637" "unprognostic (2.68e-1)" "unprognostic (2.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.14e-2)" "unprognostic (1.56e-2)" "unprognostic (5.07e-2)" "unprognostic (2.81e-2)" "unprognostic (2.50e-1)" "unprognostic (1.94e-2)" "unprognostic (6.05e-2)" "unprognostic (5.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (6.74e-2)" "unprognostic (1.14e-3)" 5.6 1.0 1.4 3.7 2.5 0.7 3.3 2.3 4.4 12.1 8.2 10.1 1.3 26.9 2.1 4.6 18.4 7.2 2.9 2.6 2.7 6.4 0.3 3.1 0.8 4.7 6.0 31.7 0.5 2.9 1.7 3.4 3.9 3.7 3.0 0.8 1.3 4.8 3.5 3.4 3.3 31.7 3.5 0.7 3.0 6.9 4.7 2.5 2.1 1.9 1.1 6.3 5.8 4.9 0.3 1.7 1.2 0.1 17.5 21.1 2.7 11.4 19.5 7.8 6.4 0.1 0.0 0.0 3.7 7.8 5.8 0.1 5.1 0.0 7.9 0.2 2.0 0.1 5.3 0.0 13.4 0.1 0.5 31.9 0.0 16.6 0.1 13.7 18.0 0.0 0.0 40.4 11.1 0.0 0.0 2.8 6.6 0.1 10.2 0.0 12.5 28.0 6.0 0.3 0.2 1.0 0.1 0.1 18.6 8.3 0.1 0.0 17.7 18.6 13.5 15.1 20.9 0.2 0.0 0.1 7.6 2.5 2.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 1.5 1.4 2.5 2.3 4.4 2.6 2.7 4.7 6.0 3.9 3.5 4.7 4.9 5.5 0.0 2.2 46.7 0.0 10.1 0.6 0.0 33.6 8.2 0.2 0.4 4.8 0.0 0.6 0.0 0.0 3.2 10.7 0.1 0.0 1.0 7.2 2.2 9.1 10.5 0.0 0.0 1.6 0.4 1.2 38.6 3.1 2.0 22.2 25.1 10.4 0.3 7.3 0.0 1.9 1.1 6.1 1.6 2.3 4.5 90.1 4.2 10.6 230.5 0.1 2.6 30.9 1.0 1.6 0.1 0.0 67.7 3.9 0.7 5.7 35.5 0.7 0.3 6.6 31.5 5.1 0.9 13.5 5.7 5.5 1.2 3.1 36.5 1.8 0.1 BOC CDON2 ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Basal squamous epithelial cells: 112.1;Fibroblasts: 55.4;Leydig cells: 84.8;Peritubular cells: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 79.2;ASC diff: 113.6;BJ hTERT+: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA No 7900000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" 41.6 5.8 15.8 10.4 15.5 0.2 29.8 13.1 12.1 26.0 33.2 49.1 4.9 46.6 10.1 24.9 63.2 19.3 14.3 17.1 15.2 9.7 1.0 6.6 3.6 53.2 30.1 35.2 16.1 2.7 20.8 2.2 23.2 33.8 4.6 3.2 23.8 21.3 6.3 34.9 18.3 32.6 32.3 4.6 19.0 5.0 26.3 5.7 24.6 9.0 3.1 32.5 25.8 23.4 0.0 7.6 27.6 79.2 113.6 6.0 0.9 12.8 41.9 3.2 2.7 0.0 0.0 0.1 7.8 21.8 1.7 0.0 5.6 2.7 1.1 0.0 3.4 0.0 2.3 0.0 0.6 0.3 0.2 19.7 1.8 1.7 0.2 25.7 0.0 0.0 0.1 0.0 0.6 2.1 0.2 1.4 7.0 0.0 6.9 0.2 12.3 0.0 0.7 0.1 8.2 11.7 0.1 0.5 0.3 8.1 3.4 0.4 0.0 4.5 7.3 0.1 4.2 0.0 0.0 0.0 9.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 15.5 13.1 12.1 17.1 15.2 53.2 30.1 23.2 32.3 26.3 23.4 9.6 0.0 0.5 71.8 0.0 21.2 3.1 3.6 112.1 0.6 3.7 17.3 1.1 1.5 0.7 5.5 0.0 4.8 0.2 0.0 0.0 0.1 1.4 12.6 10.5 5.6 1.8 0.0 8.8 0.0 4.3 55.4 0.5 11.7 0.0 5.7 3.3 0.1 0.8 0.0 2.5 0.0 0.0 0.3 5.5 3.3 84.8 1.0 10.6 6.5 0.0 12.2 0.0 24.1 0.7 0.3 0.0 47.8 0.6 3.3 0.0 0.0 0.3 0.5 0.0 18.0 13.5 1.5 3.2 11.5 11.1 1.9 0.8 1.1 0.0 0.9 C17orf58 ENSG00000186665 "Chromosome 17 open reading frame 58" Q2M2W7 17 67991099-67996469 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 35.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 55.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 37.3" HPA023036 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA023036: AB_10601144" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (6.66e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (7.65e-3)" "prognostic unfavorable (8.99e-4)" "unprognostic (7.45e-2)" "unprognostic (2.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.22e-2)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.31e-10)" "unprognostic (1.16e-2)" "unprognostic (1.04e-1)" "unprognostic (5.00e-2)" "unprognostic (1.01e-1)" 11.9 5.4 5.2 2.8 5.5 3.9 16.9 5.4 10.0 26.8 4.8 8.4 4.0 15.1 6.9 5.1 7.8 4.7 5.9 5.7 5.3 6.1 9.4 3.4 3.2 5.4 5.3 4.8 4.8 3.2 2.0 35.6 5.1 5.8 7.3 8.9 4.3 3.6 3.5 3.5 4.6 10.9 5.5 2.3 6.8 3.0 5.2 2.1 6.8 7.3 7.1 8.8 7.6 5.5 9.8 9.5 9.3 11.6 6.6 16.6 7.3 4.0 11.4 6.9 11.2 5.6 12.4 13.0 8.9 3.3 12.1 4.9 21.3 8.6 16.6 23.5 21.5 8.4 3.2 17.8 10.4 7.2 14.9 9.2 10.2 6.7 15.4 7.7 32.7 11.2 18.2 19.6 6.7 13.1 1.3 9.5 10.7 23.6 10.0 3.1 10.2 17.4 8.7 6.5 6.9 12.5 6.0 55.5 20.8 11.4 15.8 8.2 6.1 5.8 5.9 4.2 8.5 38.9 30.9 11.6 14.8 12.6 10.5 8.6 2.8 5.0 2.2 2.9 0.7 3.0 0.8 1.7 3.9 0.5 0.3 0.8 1.1 2.7 5.0 0.1 0.4 1.8 5.2 5.5 5.4 10.0 5.7 5.3 5.4 5.3 5.1 5.5 5.2 5.5 21.6 0.0 1.7 6.2 3.5 4.8 5.5 5.6 7.4 8.9 31.0 21.8 4.7 12.8 6.1 11.0 10.4 28.6 4.1 10.5 23.5 10.1 0.9 21.0 40.5 16.3 3.6 8.4 5.0 9.3 21.7 51.6 19.9 19.4 12.7 3.8 14.3 18.5 16.9 5.0 4.6 15.0 10.2 9.7 21.5 2.8 3.7 7.3 8.8 2.8 18.4 31.9 12.3 3.0 4.6 10.7 10.0 5.3 7.0 11.6 10.9 19.7 16.5 15.6 6.6 36.2 14.1 7.3 6.0 20.7 8.4 15.3 4.1 8.3 10.1 7.6 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1QTNF3 "2310005P21Rik, Corcs, Cors, Cors-26, CTRP3" ENSG00000082196 "C1q and TNF related 3" Q9BXJ4 5 34017858-34043213 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.4;salivary gland: 52.0" "Cell type enhanced" "Detected in many" "Early spermatids: 161.6;Fibroblasts: 61.5;Late spermatids: 387.6;Muller glia cells: 227.2;Skeletal myocytes: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 211 "U-266/84: 810.2" "HPA064996, HPA066011" Uncertain Approved "Golgi apparatus" "Secreted to blood" NA NA 44100000 24000000 "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA064996: AB_2685399, HPA066011: AB_2685597" "unprognostic (7.71e-2)" "unprognostic (2.81e-3)" "unprognostic (5.83e-2)" "unprognostic (6.58e-2)" "unprognostic (3.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-3)" "unprognostic (5.18e-2)" "unprognostic (1.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.89e-3)" "unprognostic (1.80e-1)" "unprognostic (9.38e-3)" "unprognostic (2.35e-1)" 7.3 0.5 4.1 1.7 5.0 0.6 6.8 6.8 4.0 3.6 2.6 11.2 3.5 2.7 1.0 33.4 3.0 5.9 0.9 3.9 7.0 4.8 1.1 4.1 0.8 5.3 4.3 1.4 1.7 0.3 1.3 0.6 4.5 2.2 10.0 23.7 52.0 4.9 2.2 2.3 8.9 23.3 5.8 0.7 10.7 11.4 4.2 1.0 1.6 9.9 0.4 13.2 3.6 5.1 0.7 0.1 0.2 0.3 0.0 0.1 0.3 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.9 0.2 0.0 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.7 0.8 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.8 3.2 0.0 0.0 0.0 1.1 0.1 0.0 0.1 0.2 0.2 1.6 0.0 0.1 0.6 0.1 0.0 3.8 0.6 0.1 1.0 0.0 1.0 0.9 810.2 1.3 0.0 0.8 3.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 4.1 5.0 6.8 4.0 3.9 7.0 5.3 4.3 4.5 5.8 4.2 5.1 2.3 3.2 2.0 0.0 2.0 5.7 0.6 0.4 1.8 5.1 3.0 2.3 1.0 8.6 0.8 3.7 0.0 0.9 1.5 0.7 1.9 1.2 161.6 2.6 1.0 7.2 1.8 1.3 0.0 1.4 0.5 61.5 1.5 2.6 0.0 1.8 0.4 1.3 1.3 8.4 0.0 1.4 2.0 0.6 9.6 387.6 1.8 1.1 7.2 0.0 0.3 227.2 1.0 0.0 0.0 0.5 1.5 2.6 0.2 0.8 0.8 2.1 1.2 11.9 0.0 77.5 4.5 6.2 2.0 1.1 5.8 0.4 1.3 1.0 2.0 0.5 C1QTNF5 "CTRP5, DKFZp586B0621, LORD" ENSG00000223953 "C1q and TNF related 5" Q9BXJ0 11 119338942-119340940 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 4.7;Endothelial cells: 1.5;Exocrine glandular cells: 1.1;Fibroblasts: 3.6;Gastric mucus-secreting cells: 1.5;Smooth muscle cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 17.7;fHDF/TERT166: 14.7;HHSteC: 35.8;hTERT-RPE1: 28.5;HUVEC TERT2: 54.7;TIME: 50.5" "Low region specificity" "Detected in all" "CAB025607, HPA038604" Uncertain "Secreted to blood" NA NA 219000000 1500000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB025607: , HPA038604: AB_2676110" 51.9 13.4 19.1 12.9 20.8 0.1 36.6 20.3 20.7 38.4 25.5 23.0 14.9 50.7 7.5 11.5 27.2 45.5 36.1 17.3 19.8 42.4 11.1 42.0 8.9 21.8 22.2 11.3 18.8 6.8 14.8 13.6 20.4 19.5 7.8 2.2 16.9 8.7 8.8 20.4 24.2 26.8 21.7 32.3 27.1 2.6 27.5 2.8 32.0 15.2 4.6 31.6 20.8 21.7 0.0 0.0 3.3 0.0 17.7 4.9 0.2 4.6 0.3 0.6 2.7 0.1 0.0 0.1 2.0 14.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 35.8 0.0 0.0 8.4 0.0 0.3 0.0 28.5 54.7 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.0 6.5 0.0 0.0 1.1 0.9 0.0 0.0 50.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 20.8 20.3 20.7 17.3 19.8 21.8 22.2 20.4 21.7 27.5 21.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 1.5 0.0 0.0 0.0 1.1 0.0 3.6 1.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 442.3;Fibroblasts: 684.4;Hepatocytes: 1444.2;Leydig cells: 1142.6;Peritubular cells: 388.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1089.8;ASC TERT1: 546.0;BJ hTERT+: 461.9;BJ hTERT+ SV40 Large T+ RasG12V: 303.4;HSkMC: 672.1" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 540.6 203.6 15.8 122.4 15.9 1.1 400.6 15.9 23.3 470.5 21.7 277.3 38.3 353.8 80.8 119.0 526.3 279.1 458.7 15.4 19.6 148.9 1425.6 340.3 72.4 23.4 19.9 644.3 88.0 11.0 63.9 52.4 18.4 205.2 100.9 5.8 158.3 87.0 69.4 177.7 228.1 157.7 18.1 192.1 242.7 46.7 18.1 34.7 223.4 74.2 75.3 468.4 394.3 18.0 1.2 8.9 0.9 9.1 1089.8 546.0 0.4 108.9 461.9 143.0 303.4 1.4 2.4 0.5 4.5 108.8 11.8 2.3 11.8 5.5 18.3 18.3 1.1 0.5 4.1 3.6 226.5 0.8 2.3 672.1 3.2 74.7 4.7 121.0 2.9 0.5 0.3 20.5 21.2 0.1 8.0 0.8 3.1 0.1 0.9 8.6 3.8 0.8 0.9 5.5 0.4 2.3 95.1 3.7 2.8 1.3 0.2 0.2 0.4 38.3 6.3 152.1 0.8 1.1 3.0 0.2 53.1 1.0 5.4 0.0 0.0 0.6 0.3 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.6 0.6 0.5 0.8 0.0 0.0 0.3 0.1 15.8 15.9 15.9 23.3 15.4 19.6 23.4 19.9 18.4 18.1 18.1 18.0 45.4 22.4 90.5 3.6 7.1 54.7 58.8 76.6 33.6 0.3 5.9 30.9 20.8 183.0 22.9 18.4 2.1 4.1 1.8 0.7 3.9 280.8 4.6 13.3 442.3 45.4 0.0 40.6 0.9 44.5 3.7 684.4 16.3 11.6 10.1 24.9 114.9 1444.2 11.2 0.0 0.3 0.7 0.0 40.9 66.9 29.2 1142.6 7.0 53.4 13.1 1.6 16.0 0.0 2.5 0.1 51.1 1.3 388.1 6.2 17.7 0.3 6.1 5.3 1.4 170.9 87.5 140.4 6.8 6.7 5.6 40.1 5.2 11.5 15.2 0.7 11.2 C21orf62 "B37, C21orf120, PRED81" ENSG00000205929 "Chromosome 21 open reading frame 62" Q9NYP8 21 32790673-32813743 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 19.7;ovary: 14.2" "Group enriched" "Detected in many" 4 "Cholangiocytes: 44.3;Distal tubular cells: 23.5;Skeletal myocytes: 26.2" "Cancer enriched" "Detected in some" 6 "glioma: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 3.8;RPTEC TERT1: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016899 Enhanced "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA016899: AB_1845704" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (1.23e-1)" "unprognostic (4.37e-3)" "unprognostic (9.56e-2)" "unprognostic (3.05e-3)" "unprognostic (2.95e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.59e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" 1.6 0.3 1.7 0.4 2.2 0.5 0.1 1.8 2.0 0.0 19.7 0.1 0.1 0.0 8.4 0.2 0.7 0.4 0.2 2.4 4.1 6.9 0.2 0.1 0.2 3.2 7.2 14.2 4.1 0.0 3.4 0.0 2.8 3.6 0.0 1.0 0.1 0.2 0.1 0.2 0.4 0.2 2.0 0.2 0.3 0.3 4.6 0.0 0.1 0.1 1.1 0.0 0.1 5.8 0.0 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.7 0.2 0.0 0.1 0.3 0.0 1.7 2.2 1.8 2.0 2.4 4.1 3.2 7.2 2.8 2.0 4.6 5.8 0.0 0.0 0.0 2.9 0.5 0.9 0.8 0.4 0.0 5.9 0.0 0.0 0.2 44.3 0.3 5.5 6.2 1.2 1.3 0.1 23.5 0.2 1.5 0.0 0.0 0.8 3.0 0.0 0.8 0.0 0.4 3.6 0.0 0.0 0.0 0.2 2.5 0.2 0.3 0.0 1.4 0.0 0.0 1.3 1.9 0.3 4.1 0.4 3.6 0.0 1.0 5.8 4.1 4.0 4.7 0.0 0.0 1.9 0.0 0.5 0.1 2.6 0.2 7.1 0.0 26.2 1.7 1.0 1.0 0.0 1.0 0.3 1.1 0.2 0.2 0.4 C3orf33 "AC3-33, FLJ31139" ENSG00000174928 "Chromosome 3 open reading frame 33" Q6P1S2 3 155762617-155806278 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037663 Uncertain "Secreted in other tissues" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA037663: AB_10672610" "unprognostic (1.18e-1)" "unprognostic (9.39e-3)" "unprognostic (1.48e-1)" "unprognostic (1.66e-3)" "unprognostic (1.31e-1)" "unprognostic (7.27e-2)" "unprognostic (6.31e-3)" "unprognostic (3.28e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic favorable (6.48e-7)" "unprognostic (3.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.24e-2)" "unprognostic (1.56e-1)" 2.7 10.7 5.2 1.3 5.6 2.0 4.2 5.3 7.8 4.0 6.2 3.1 2.6 3.7 5.8 1.7 3.9 2.3 6.1 5.5 5.5 6.2 3.1 3.3 1.6 5.4 5.5 4.5 6.7 7.5 4.9 1.3 5.4 4.4 2.3 2.7 3.2 3.9 4.9 1.3 2.2 3.3 5.4 2.3 3.1 4.1 5.8 1.5 8.7 4.4 1.0 2.7 2.5 5.4 5.5 7.5 3.6 4.9 0.3 4.4 1.5 2.4 3.5 2.2 5.2 2.6 6.9 0.9 5.3 2.3 3.3 0.8 3.7 0.0 3.9 2.7 5.4 3.3 1.0 7.0 6.0 4.8 1.1 3.4 4.0 2.4 4.6 2.8 3.8 5.5 5.4 2.4 3.8 4.1 4.9 4.0 4.6 5.2 1.8 4.8 1.8 5.2 12.2 2.7 2.6 3.6 5.3 6.7 4.6 1.8 9.8 5.7 2.3 2.5 1.8 5.5 5.9 4.1 4.3 0.0 1.8 4.4 2.6 2.1 1.2 0.2 4.0 1.1 5.1 1.8 3.1 3.6 2.1 1.4 3.9 4.1 0.1 4.0 0.8 1.7 2.2 2.1 5.2 5.6 5.3 7.8 5.5 5.5 5.4 5.5 5.4 5.4 5.8 5.4 1.6 3.2 6.7 13.7 1.5 1.3 5.2 4.7 5.2 8.5 3.1 2.7 11.9 5.7 6.7 0.0 6.2 4.2 0.9 1.8 5.9 3.7 6.6 1.5 2.7 2.3 3.6 3.8 14.9 3.3 3.1 4.8 1.1 1.4 7.0 2.8 2.5 3.3 2.4 6.7 14.9 3.8 4.1 0.3 2.0 5.4 6.2 1.4 1.8 3.7 0.6 15.6 6.2 11.6 10.7 1.4 2.5 7.9 2.2 5.1 1.0 7.0 3.5 7.6 0.0 8.4 4.1 14.5 14.8 2.7 1.4 3.7 2.8 3.8 3.7 2.5 C5orf58 ENSG00000234511 "Chromosome 5 open reading frame 58" C9J3I9 5 170232447-170252575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 35 "testis: 216.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.3" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 12 "U-266/84: 85.6" "Not detected" "Not detected" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (9.24e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-2)" "unprognostic (5.55e-2)" "unprognostic (2.92e-1)" "unprognostic (1.35e-1)" "unprognostic (5.33e-6)" "unprognostic (1.01e-1)" "unprognostic (5.61e-2)" "unprognostic (8.48e-2)" "unprognostic (1.85e-1)" "unprognostic (2.78e-1)" "unprognostic (3.29e-10)" "unprognostic (4.83e-3)" "unprognostic (5.45e-2)" "unprognostic (3.94e-2)" "unprognostic (8.27e-2)" 3.1 0.7 0.1 2.7 0.3 6.2 2.5 0.2 2.2 1.3 0.4 0.8 0.6 0.5 0.0 0.4 0.7 1.1 0.9 0.1 0.1 0.6 1.0 4.9 2.2 0.8 0.5 0.4 0.3 0.0 0.6 1.2 1.1 1.0 0.0 0.0 1.9 0.0 0.5 0.9 1.4 0.0 0.4 3.6 0.6 216.4 0.8 0.0 0.9 0.0 0.1 0.9 1.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 3.5 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.9 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 6.9 0.8 0.0 0.0 0.0 0.0 0.0 2.6 85.6 0.0 0.0 1.0 0.0 0.0 0.2 0.5 0.6 0.3 0.4 0.0 0.4 0.6 0.0 0.0 0.3 0.9 1.0 0.6 0.3 0.0 0.0 0.0 0.1 0.3 0.2 2.2 0.1 0.1 0.8 0.5 1.1 0.4 0.8 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 CAB39L "bA103J18.3, FLJ12577, MO2L" ENSG00000102547 "Calcium binding protein 39 like" Q9H9S4 13 49308650-49444064 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 200.0" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 41.8;RT4: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003686, HPA045954, HPA076632" Approved Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB003686: AB_426084, HPA045954: AB_2679512, HPA076632: " "unprognostic (3.90e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-1)" "unprognostic (5.01e-1)" "unprognostic (3.29e-1)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (2.94e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (3.08e-2)" "prognostic favorable (7.91e-4)" "prognostic favorable (1.94e-13)" "unprognostic (6.59e-2)" "unprognostic (8.31e-2)" "unprognostic (4.96e-2)" "unprognostic (8.05e-3)" 23.7 37.4 25.0 4.4 26.4 2.2 37.3 21.0 20.7 14.5 68.2 57.7 6.0 15.3 16.3 31.2 18.3 16.5 22.0 24.6 38.7 14.0 5.3 19.5 4.2 24.6 35.0 21.5 12.0 29.2 8.4 12.4 25.1 41.4 11.6 14.8 16.9 22.5 7.5 16.1 12.5 11.5 27.4 4.0 27.1 33.4 31.4 9.4 9.7 13.0 5.2 26.5 17.3 28.4 1.6 1.7 9.8 2.8 9.3 8.7 14.8 9.3 17.9 5.9 4.1 41.8 6.0 14.2 1.2 6.5 6.5 3.4 5.4 6.2 10.2 4.7 4.5 3.7 2.0 2.6 5.2 3.3 1.6 6.4 4.8 4.4 6.8 7.3 8.0 2.2 0.7 3.2 8.1 2.8 3.2 2.4 7.6 5.4 2.7 2.8 1.3 2.3 8.3 43.4 1.2 3.7 5.1 11.8 12.1 11.8 18.4 4.9 7.6 2.5 2.7 5.3 7.6 2.5 2.3 16.3 2.8 2.5 5.7 6.7 2.6 5.4 2.6 2.4 2.0 2.7 3.2 3.4 2.6 1.6 2.3 2.3 5.6 1.9 2.1 0.4 3.6 2.3 25.0 26.4 21.0 20.7 24.6 38.7 24.6 35.0 25.1 27.4 31.4 28.4 6.9 16.0 11.9 52.2 2.4 3.1 12.6 6.6 7.4 6.4 27.1 14.4 14.5 4.3 13.4 11.0 6.2 26.4 3.1 3.9 11.7 10.1 200.0 8.3 9.2 5.4 2.4 1.7 45.0 10.6 14.0 42.5 5.6 3.7 4.5 4.2 3.9 1.9 6.4 1.7 32.4 2.4 16.2 3.5 4.7 32.1 15.5 5.0 12.4 24.4 5.6 14.9 7.2 50.3 43.3 10.3 2.0 11.7 4.6 16.7 0.8 5.0 17.7 5.2 6.6 9.4 16.8 46.0 5.0 16.0 4.4 29.0 3.6 3.9 2.3 21.7 CALCR CTR ENSG00000004948 "Calcitonin receptor" 7 93424486-93574730 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;kidney: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.5;Late spermatids: 7.7;Microglial cells: 15.9;Skeletal myocytes: 46.0" "Cancer enriched" "Detected in single" 5 "renal cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.6;SuSa: 2.9;T-47d: 2.7" "Group enriched" "Detected in many" 5 "basal ganglia: 6.3;hypothalamus: 24.6" "Low region specificity" "Detected in all" "HPA028962, HPA061428" Enhanced Supported Approved "Vesicles,Cell Junctions,Centriolar satellite" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "Vesicles, Centriolar satellite" "HPA028962: AB_10602339, HPA061428: AB_2732661" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "unprognostic (3.88e-2)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.43e-1)" "unprognostic (7.73e-5)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (8.70e-2)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (2.71e-3)" "unprognostic (1.46e-3)" "unprognostic (1.69e-1)" "unprognostic (2.49e-4)" "unprognostic (1.05e-2)" 0.1 0.2 1.6 0.0 0.5 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 5.8 1.5 0.0 0.2 0.0 1.8 1.6 0.2 0.0 0.0 0.1 0.6 3.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 2.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.2 0.0 5.8 1.8 1.6 3.4 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.8 0.6 7.7 0.6 0.6 0.0 15.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 3.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 75.1;Fibroblasts: 38.2;Hepatic stellate cells: 48.2;Hofbauer cells: 53.7;Leydig cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 45.1;BJ: 37.7;BJ hTERT+: 37.5;fHDF/TERT166: 43.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" 49.7 18.5 7.2 12.5 6.5 2.1 38.9 6.3 9.0 54.4 7.0 18.4 6.5 58.1 5.5 12.2 43.3 21.6 34.2 7.0 7.3 10.7 4.5 23.2 13.7 8.0 6.4 48.1 7.1 3.1 7.3 10.0 7.8 21.1 4.3 0.4 14.9 10.6 9.7 17.9 19.6 15.9 7.7 35.3 13.8 11.5 8.0 5.6 21.6 11.1 6.1 33.9 39.3 7.9 11.0 7.5 1.8 2.4 27.3 45.1 9.1 37.7 37.5 11.2 15.7 3.3 5.3 3.3 4.2 43.2 0.7 5.0 3.8 0.0 2.1 0.4 21.5 7.8 2.5 0.6 12.4 1.3 0.7 15.6 0.0 3.3 0.1 20.8 13.5 8.3 1.8 19.8 7.5 25.0 3.0 3.7 4.8 2.3 6.7 9.2 3.0 7.5 1.0 0.9 5.3 2.3 1.5 6.2 2.1 0.8 1.2 2.5 24.5 3.6 4.4 12.6 2.7 3.0 7.6 3.8 31.0 24.0 0.8 70.0 91.9 1.8 83.7 178.4 69.6 27.7 56.5 69.7 152.1 7.3 10.8 42.3 3.6 62.9 214.6 17.8 82.7 85.6 7.2 6.5 6.3 9.0 7.0 7.3 8.0 6.4 7.8 7.7 8.0 7.9 18.2 3.2 0.6 1.0 4.9 5.4 2.9 0.6 4.0 0.1 3.4 4.4 3.3 1.5 0.0 3.7 0.0 3.1 11.3 0.1 0.0 4.2 1.0 1.4 19.8 25.5 1.2 5.7 2.3 0.2 75.1 38.2 1.5 2.1 8.8 11.4 48.2 0.6 53.7 0.0 0.5 0.1 2.0 28.8 18.8 2.5 45.7 21.5 8.8 2.8 17.3 0.2 33.0 1.0 0.2 0.1 0.1 16.1 3.1 0.8 0.0 0.3 0.0 0.1 19.7 16.8 27.9 0.8 0.9 0.8 3.8 19.2 19.4 6.0 0.0 1.0 CARMIL1 "CARMIL, dJ501N12.1, FLJ20048, LRRC16, LRRC16A" ENSG00000079691 "Capping protein regulator and myosin 1 linker 1" Q5VZK9 6 25279078-25620530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 27.9;Collecting duct cells: 35.0;Distal tubular cells: 46.9;Endometrial ciliated cells: 37.3;Glandular and luminal cells: 39.3;Granulosa cells: 31.8;Proximal tubular cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 36.0;RPTEC TERT1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029038, HPA029039" Enhanced Supported Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA029038: AB_10601668, HPA029039: AB_10611382" "unprognostic (2.34e-2)" "unprognostic (9.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.71e-2)" "unprognostic (3.94e-2)" "unprognostic (2.22e-1)" "unprognostic (1.66e-3)" "unprognostic (3.82e-1)" "unprognostic (4.02e-1)" "unprognostic (7.15e-3)" "unprognostic (8.25e-3)" "unprognostic (5.86e-2)" "unprognostic (1.28e-3)" "unprognostic (3.08e-2)" "unprognostic (2.53e-1)" "unprognostic (1.07e-1)" "unprognostic (2.31e-1)" 4.4 3.9 2.7 2.8 4.1 0.7 6.5 6.4 5.9 5.2 0.0 10.7 15.3 2.5 7.1 4.3 5.5 5.8 3.7 2.2 2.5 8.5 2.1 8.0 3.6 1.0 3.5 4.3 4.5 5.1 1.2 4.6 0.8 3.3 10.0 1.0 5.3 2.7 0.4 5.9 15.8 2.7 1.3 2.8 7.4 11.4 3.2 7.6 5.2 2.0 3.7 5.2 3.7 1.2 12.9 12.7 3.5 4.5 3.2 1.6 12.1 4.3 9.7 4.5 7.9 13.7 9.4 4.4 13.8 6.9 13.2 13.7 13.6 12.2 3.3 11.1 7.2 10.7 14.0 1.7 8.9 0.5 1.6 1.7 8.2 8.7 13.3 5.6 0.2 1.6 0.3 3.5 2.9 10.0 0.7 0.0 4.8 22.7 5.2 1.5 2.1 36.0 34.7 11.5 9.0 1.9 19.1 32.4 12.4 10.1 7.8 0.3 0.2 3.3 5.8 15.8 4.4 0.5 0.2 7.0 5.2 3.9 12.6 0.0 0.4 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.4 1.3 1.0 0.1 0.0 0.6 1.3 0.9 0.0 0.1 2.7 4.1 6.4 5.9 2.2 2.5 1.0 3.5 0.8 1.3 3.2 1.2 3.2 19.2 27.9 0.0 7.7 0.0 0.0 0.0 0.0 0.0 17.5 11.6 0.0 0.0 4.3 35.0 0.0 20.8 0.4 0.0 46.9 16.7 0.0 37.3 7.0 4.0 0.0 0.0 0.0 15.6 7.9 12.8 0.0 39.3 8.8 31.8 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 17.6 0.0 0.0 7.6 0.0 0.0 58.8 3.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 10.9 1.6 14.9 0.0 0.0 CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 93.9" "Cell type enhanced" "Detected in some" "dendritic cells: 3.0;Theca cells: 5.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 11 "cerebellum: 93.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 13.4;HDLM-2: 17.2;HSkMC: 23.3;Karpas-707: 18.3;U-266/70: 12.8" "Region enriched" "Detected in many" 25 "cerebellum: 429.5" "Region enriched" "Detected in many" 42 "cerebellum: 446.5" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA041266: AB_10674430" "unprognostic (5.02e-2)" "unprognostic (3.26e-1)" "unprognostic (1.43e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.39e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (6.20e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (6.20e-6)" "unprognostic (2.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (9.02e-2)" 7.3 17.1 2.7 8.3 3.0 0.6 4.7 93.9 7.0 4.6 2.1 4.2 2.1 2.7 7.4 2.9 4.0 5.6 3.7 2.4 3.3 4.4 6.0 4.8 13.7 3.9 5.8 10.1 2.0 2.9 4.2 3.7 8.4 4.5 2.1 0.5 4.3 3.1 1.8 3.5 5.4 2.2 3.2 13.7 3.3 5.1 3.4 3.9 4.5 0.6 9.1 4.9 4.6 4.8 1.5 1.3 0.7 2.5 6.2 13.4 0.4 5.5 11.1 2.1 2.7 0.7 2.6 2.4 1.2 3.4 2.4 0.3 0.8 2.9 1.4 17.2 0.6 0.0 5.2 1.1 3.3 0.4 0.9 23.3 1.3 2.7 2.1 8.8 1.9 1.0 0.7 18.3 2.8 0.8 0.0 0.7 0.1 1.5 1.5 0.0 0.0 1.8 1.2 0.5 0.9 0.5 0.5 0.1 0.8 0.3 0.8 0.6 8.7 7.7 1.5 3.2 0.3 12.8 3.2 2.7 0.4 1.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.0 93.9 7.0 2.4 3.3 3.9 5.8 8.4 3.2 3.4 4.8 1.4 0.0 0.0 0.0 2.6 0.4 0.6 1.5 0.0 0.0 0.8 1.0 0.5 0.0 0.4 0.0 0.0 0.9 3.0 0.8 0.0 1.1 0.0 0.3 2.0 0.8 0.0 0.4 0.3 1.1 0.6 2.6 0.0 0.5 0.0 0.9 0.0 0.2 0.9 0.0 0.1 0.5 0.0 0.3 0.4 0.3 2.5 0.7 0.0 1.0 2.6 1.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 0.5 0.9 0.8 1.4 0.2 0.0 0.7 1.4 0.0 0.2 0.2 0.6 0.8 0.2 5.7 0.6 0.6 CCDC71L "C7orf74, FLJ36031" ENSG00000253276 "Coiled-coil domain containing 71 like" Q8N9Z2 7 106654360-106661158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067925 Approved Approved "Golgi apparatus,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Actin filaments" Cytosol "HPA067925: AB_2685925" "unprognostic (1.51e-1)" "prognostic unfavorable (9.08e-4)" "unprognostic (7.26e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-2)" "unprognostic (1.95e-3)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (2.38e-3)" "unprognostic (6.03e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.53e-6)" "unprognostic (3.34e-2)" "unprognostic (3.72e-1)" "unprognostic (2.26e-1)" "unprognostic (6.35e-2)" 51.5 9.8 2.7 19.6 2.7 15.8 18.7 2.0 2.9 13.1 3.3 14.6 6.5 16.9 2.8 6.8 36.2 10.8 8.2 2.9 3.2 18.1 46.7 22.1 9.6 8.2 2.8 10.1 9.3 5.2 6.4 3.7 3.7 11.2 5.4 1.0 12.6 6.6 5.3 6.2 15.8 7.2 3.3 18.7 16.3 6.9 4.6 14.5 10.2 2.5 8.0 40.0 9.3 3.6 24.8 5.1 7.4 8.9 16.3 15.4 0.0 37.0 47.5 14.2 15.4 0.7 15.3 16.5 12.6 63.3 27.1 2.8 3.6 10.7 11.7 38.7 8.5 2.1 0.9 0.0 25.5 8.4 19.4 13.2 6.4 6.5 3.7 24.1 50.0 9.2 56.0 39.9 17.1 7.1 11.5 13.3 16.0 2.0 17.0 15.4 2.1 3.3 7.3 1.4 3.2 22.1 23.9 8.6 55.9 15.4 3.9 10.1 22.0 31.4 2.9 3.7 14.6 38.4 3.8 13.5 24.3 10.8 35.3 4.9 0.6 1.8 1.1 0.4 0.8 1.3 0.8 0.8 0.4 0.9 0.4 0.6 4.1 0.6 0.7 1.4 1.7 0.5 2.7 2.7 2.0 2.9 2.9 3.2 8.2 2.8 3.7 3.3 4.6 3.6 44.0 3.2 11.6 1.0 9.4 8.2 50.5 2.1 6.8 4.3 39.9 33.0 6.2 18.6 1.6 5.5 2.1 3.0 26.2 12.9 11.7 7.4 1.2 18.7 78.7 21.4 6.6 11.6 1.8 10.7 7.4 47.8 3.6 20.2 12.0 3.3 45.7 34.4 8.1 6.7 2.8 7.3 4.1 10.0 13.9 2.1 21.8 22.5 12.4 1.9 6.5 5.0 10.3 2.5 1.8 13.9 10.1 17.7 4.3 11.0 10.1 4.7 6.8 4.8 0.0 24.5 30.1 7.1 4.9 4.0 5.1 3.3 13.7 3.4 9.5 18.3 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCL11 "eotaxin, MGC22554, SCYA11" ENSG00000172156 "C-C motif chemokine ligand 11" P51671 17 34285742-34288334 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.7;lymphoid tissue: 31.4;stomach 1: 35.1;urinary bladder: 41.0" "Cell type enriched" "Detected in some" 15 "Fibroblasts: 38.9" "Cancer enhanced" "Detected in many" "stomach cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "BJ hTERT+: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 88500 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.61e-2)" "unprognostic (1.45e-1)" "prognostic favorable (8.70e-4)" "unprognostic (8.18e-2)" "prognostic favorable (1.99e-4)" "unprognostic (9.91e-2)" "unprognostic (8.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (1.45e-1)" "unprognostic (9.64e-8)" "unprognostic (2.66e-2)" "unprognostic (1.05e-3)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" 3.8 0.8 0.0 31.4 0.0 0.0 0.2 0.0 0.0 3.6 0.0 41.7 33.2 1.7 0.0 12.4 0.7 4.8 16.7 0.0 0.0 5.8 0.6 9.1 0.0 0.0 0.0 0.3 2.8 1.7 1.0 0.0 0.0 2.6 14.7 0.0 0.1 0.9 0.0 0.0 35.8 20.5 0.0 2.8 35.1 0.0 0.0 0.3 0.0 0.0 0.7 41.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 9.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 1.9 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.1 CCN1 "CYR61, GIG1, IGFBP10" ENSG00000142871 "Cellular communication network factor 1" O00622 1 85580761-85584589 "Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 256.5;Cardiomyocytes: 107.6;Cytotrophoblasts: 258.1;Extravillous trophoblasts: 529.9;Fibroblasts: 296.2;Syncytiotrophoblasts: 131.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebral cortex: 25.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 431.8;BJ hTERT+ SV40 Large T+: 422.0;EFO-21: 410.9;SiHa: 551.2;TIME: 541.3;U-251 MG: 642.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029853 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA029853: AB_10611822" "unprognostic (6.09e-2)" "unprognostic (3.25e-2)" "unprognostic (9.97e-2)" "unprognostic (8.90e-2)" "unprognostic (1.80e-2)" "unprognostic (3.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.56e-2)" "unprognostic (2.59e-1)" "unprognostic (9.95e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (3.74e-3)" 571.1 99.7 1.0 28.2 3.9 0.2 313.4 1.0 25.0 255.7 9.6 197.1 5.1 273.6 0.1 48.7 472.4 64.8 400.6 3.7 0.0 212.8 200.5 407.8 3.8 4.9 3.8 123.1 70.7 14.8 56.0 29.8 3.1 157.3 1.7 1.1 94.2 2.9 97.8 197.1 102.0 141.7 0.0 131.2 201.7 20.1 5.1 11.1 268.1 17.3 0.0 264.4 150.8 3.6 159.3 5.2 0.7 1.0 47.4 90.6 77.4 431.8 216.6 422.0 264.6 24.1 4.3 0.0 410.9 185.5 82.8 36.3 15.9 33.4 164.4 0.7 6.9 0.3 6.8 0.7 245.2 3.7 0.2 39.9 6.9 121.2 50.1 13.4 366.0 0.1 1.6 0.0 150.3 0.8 0.3 0.7 24.9 1.8 42.2 0.4 94.9 0.7 166.0 2.5 0.4 4.0 551.2 17.7 62.1 4.9 16.5 0.8 541.3 272.3 213.3 82.2 642.6 0.3 0.7 1.8 1.9 0.2 73.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.9 1.0 25.0 3.7 0.0 4.9 3.8 3.1 0.0 5.1 3.6 256.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.6 0.0 0.0 0.0 0.0 258.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 529.9 296.2 0.0 0.0 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 89.1 0.0 0.0 0.0 0.0 131.3 0.0 0.0 0.0 0.0 CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 101.2;Cardiomyocytes: 38.7;Extravillous trophoblasts: 47.1;Fibroblasts: 261.8;Smooth muscle cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Cell line enhanced" "Detected in many" "EFO-21: 1605.0;HUVEC TERT2: 1377.0;TIME: 2874.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" No No 1010000 5900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 265.9 107.5 18.9 168.0 18.8 2.0 206.4 16.3 34.0 531.0 31.5 148.8 43.7 418.5 34.4 271.9 243.8 441.4 371.8 25.8 14.2 235.7 82.9 226.3 73.6 18.8 32.1 77.0 194.0 43.0 44.8 198.2 20.2 364.6 136.1 2.4 138.2 154.3 51.8 155.1 151.2 576.3 14.2 569.1 182.6 24.7 20.8 49.5 464.7 61.9 14.9 324.0 102.5 18.2 4.6 7.5 126.8 3.7 279.9 158.5 1.8 373.1 178.2 226.8 119.4 0.2 12.2 0.6 1605.0 482.7 185.0 6.2 4.2 26.4 211.3 2.5 3.5 0.2 55.7 137.3 109.6 0.3 0.5 232.2 5.9 163.9 40.2 340.7 1377.0 0.0 0.4 0.3 650.8 2.5 0.5 1.2 61.8 41.3 21.7 32.6 6.0 0.7 81.9 0.4 0.5 0.8 38.3 62.2 18.3 308.5 6.1 3.1 2874.4 311.6 242.4 397.8 694.0 11.5 1.7 4.1 42.5 0.7 399.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.9 18.8 16.3 34.0 25.8 14.2 18.8 32.1 20.2 14.2 20.8 18.2 101.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 0.0 17.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 47.1 261.8 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in some" "Adipocytes: 25.2;Endothelial cells: 2.7;Fibroblasts: 9.8;Smooth muscle cells: 4.6" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.0;hTERT-RPE1: 38.1;U-2197: 128.2" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 23.7 1105.4 7.6 3.6 11.5 1.7 8.1 6.7 12.2 11.2 5.9 6.9 3.9 8.6 6.3 5.5 9.0 6.3 18.1 16.2 9.7 6.9 1.1 6.8 2.2 5.6 6.5 3.1 6.8 9.4 21.8 0.6 4.9 22.8 7.0 1.2 2.7 20.0 4.7 13.8 4.4 8.4 8.7 1.5 4.9 3.6 6.3 1.0 25.3 7.2 1.9 4.4 8.0 6.2 0.1 3.1 1.7 0.0 11.1 2.9 0.1 16.9 125.0 14.9 8.6 0.0 0.3 0.0 12.9 21.2 11.6 10.5 0.6 0.0 5.1 0.0 0.3 0.0 9.1 0.0 0.4 0.0 0.0 0.6 0.1 5.7 0.6 38.1 0.4 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.2 1.2 24.9 0.1 0.0 0.0 15.8 0.1 3.9 0.1 6.3 0.1 24.2 0.0 0.0 0.0 0.0 10.6 15.8 128.2 3.5 0.0 0.0 0.0 16.7 5.4 12.5 0.0 0.3 64.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.1 7.6 11.5 6.7 12.2 16.2 9.7 5.6 6.5 4.9 8.7 6.3 6.2 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCN5 "CT58, CTGF-L, WISP-2, WISP2" ENSG00000064205 "Cellular communication network factor 5" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 394.6;cervix: 355.7" "Cell type enriched" "Detected in some" 6 "Fibroblasts: 165.2" "Cancer enhanced" "Detected in many" "melanoma: 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 42.6;ASC TERT1: 113.8;HeLa: 62.7;HSkMC: 46.5;U-2197: 375.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB019273 Approved "Secreted to extracellular matrix" NA NA 1200000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB019273: " "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.42e-2)" "unprognostic (2.81e-1)" "unprognostic (7.95e-3)" "unprognostic (1.76e-10)" "unprognostic (1.55e-3)" "unprognostic (7.21e-2)" "unprognostic (4.84e-2)" "unprognostic (1.28e-1)" 394.6 41.5 1.8 0.7 2.0 0.2 116.5 0.9 2.9 355.7 0.7 23.6 0.7 35.3 0.7 25.4 39.0 7.7 161.1 1.6 1.3 0.7 5.6 136.4 1.9 1.4 1.4 147.1 4.4 0.6 0.8 1.4 1.4 37.0 1.6 0.1 30.7 25.5 39.2 197.1 11.5 6.5 1.0 4.0 11.4 33.1 1.4 1.3 14.2 5.1 0.4 36.7 111.6 1.5 0.0 3.7 0.1 0.0 42.6 113.8 0.0 0.2 1.2 0.1 0.2 0.0 0.0 0.1 0.5 0.7 3.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 62.7 0.0 0.1 0.1 0.1 46.5 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 1.1 0.3 0.0 1.9 0.2 0.0 0.1 0.2 375.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.0 0.9 2.9 1.6 1.3 1.4 1.4 1.4 1.0 1.4 1.5 25.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 165.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD81 "TAPA-1, TAPA1, TSPAN28" ENSG00000110651 "CD81 molecule" P60033 11 2376177-2397397 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1003.1;Endometrial stromal cells: 1050.9;Muller glia cells: 809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 148.9;naive B-cell: 137.2" "Lineage enriched" "Detected in all" 4 "B-cells: 148.9" "Cell line enhanced" "Detected in many" "ASC diff: 2960.6;fHDF/TERT166: 1752.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002507, HPA007234" Supported Supported "Plasma membrane,Cytosol" NA NA 400000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "CAB002507: AB_563639, HPA007234: AB_1846333" "unprognostic (2.96e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.07e-3)" "unprognostic (2.08e-1)" "unprognostic (3.55e-2)" "unprognostic (1.67e-1)" "unprognostic (2.06e-1)" "unprognostic (2.06e-1)" 892.1 299.1 560.6 270.7 598.4 77.8 773.6 614.8 590.2 952.7 498.9 992.0 150.7 1384.0 960.5 364.3 853.1 534.5 937.9 511.1 615.8 636.6 1175.7 768.4 429.0 665.7 640.8 656.8 449.5 258.3 409.1 441.0 651.1 634.0 234.4 75.9 531.1 1602.0 214.3 511.1 423.1 978.5 694.1 631.3 494.3 316.9 655.1 158.9 564.6 227.6 278.6 749.2 763.4 734.4 337.0 342.0 268.5 413.4 2960.6 1668.4 224.8 621.0 1361.6 490.3 492.2 322.8 1.8 285.4 218.3 1752.6 312.5 430.5 167.3 442.2 199.9 135.6 517.8 43.7 117.1 0.3 976.4 188.2 359.8 1222.3 619.9 201.1 302.1 757.9 476.6 204.0 198.7 484.9 696.4 257.2 160.7 239.1 324.4 304.7 274.2 324.7 135.5 183.3 529.1 223.3 288.8 319.2 198.4 514.4 383.8 214.3 171.0 337.8 641.3 249.0 181.6 471.2 216.6 356.9 88.1 529.1 361.3 111.0 435.0 0.9 3.3 22.9 21.1 5.8 34.4 148.9 14.9 33.0 2.6 137.2 9.2 16.9 1.0 14.7 7.3 7.7 12.0 10.7 560.6 598.4 614.8 590.2 511.1 615.8 665.7 640.8 651.1 694.1 655.1 734.4 1003.1 243.6 270.0 95.0 88.2 179.8 391.8 89.7 26.2 82.7 325.6 452.0 277.4 167.3 102.3 207.8 27.1 21.8 267.1 20.0 35.2 105.7 15.9 365.4 1050.9 344.5 71.9 30.7 19.0 55.1 31.7 560.4 21.4 462.7 81.7 204.0 293.4 603.9 251.5 148.0 32.4 48.2 50.8 232.7 179.7 50.2 389.2 277.6 151.2 60.0 23.0 809.2 45.3 145.8 93.6 61.3 14.7 251.3 50.7 147.6 5.0 29.9 85.8 76.1 118.3 356.9 423.6 15.6 19.4 30.6 164.9 20.1 136.8 379.0 41.5 298.1 CDH15 "CDH14, CDH3" ENSG00000129910 "Cadherin 15" P55291 16 89171748-89195492 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 24.4;skeletal muscle: 57.0" "Cell type enriched" "Detected in some" 13 "Skeletal myocytes: 76.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 15 "cerebellum: 24.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RH-30: 145.8" "Region enriched" "Detected in many" 7 "cerebellum: 15.7" "Region enriched" "Detected in some" 17 "cerebellum: 18.7" "HPA009139, HPA070961" Enhanced Supported Enhanced "Golgi apparatus,Plasma membrane" NA NA 870000 "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" "HPA009139: AB_1078372, HPA070961: AB_2686328" "unprognostic (1.26e-1)" "unprognostic (7.70e-3)" "unprognostic (6.64e-3)" "unprognostic (2.81e-1)" "unprognostic (7.79e-3)" "unprognostic (2.70e-3)" "unprognostic (2.84e-3)" "unprognostic (4.37e-2)" "unprognostic (2.30e-3)" "unprognostic (7.66e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.14e-7)" "unprognostic (3.09e-2)" "unprognostic (3.13e-1)" "unprognostic (5.50e-2)" "unprognostic (2.64e-2)" 0.0 0.2 0.1 0.0 0.2 0.0 0.0 24.4 0.8 1.3 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.1 1.3 0.4 0.0 0.1 0.8 0.2 1.4 0.0 0.1 0.7 1.6 0.4 0.0 0.0 0.9 0.0 57.0 0.1 0.0 0.0 0.3 1.2 0.2 0.6 0.1 0.0 0.0 5.3 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.7 0.0 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 31.5 0.1 0.0 0.1 0.0 0.2 0.3 0.0 145.8 0.3 0.0 0.0 0.8 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 24.4 0.8 0.0 0.1 0.1 0.8 1.6 0.3 0.1 0.6 0.2 0.0 2.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.1 1.0 0.1 1.2 0.0 0.1 0.0 0.3 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.0 76.1 0.4 1.5 5.5 0.0 0.0 0.1 0.2 0.8 0.1 0.1 CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.3;Fibroblasts: 23.5;Inhibitory neurons: 49.5;Muller glia cells: 39.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;ASC diff: 32.7;RH-30: 48.9;SuSa: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" 12.6 0.7 1.9 1.6 2.0 0.0 5.1 23.0 4.0 7.9 1.2 12.4 1.0 14.0 2.1 1.7 14.2 4.8 4.0 1.6 1.8 0.8 1.2 2.7 1.1 2.2 1.9 20.6 1.2 2.5 3.0 2.7 2.7 1.3 1.6 10.1 1.7 2.8 1.2 9.9 2.9 17.0 0.5 0.7 4.6 3.6 2.3 2.8 18.5 1.6 1.5 2.5 3.0 2.1 1.6 3.2 28.4 2.8 32.7 14.5 0.4 0.5 2.9 0.9 0.3 1.1 9.4 1.4 6.8 0.6 3.3 0.4 7.1 1.0 0.8 5.5 6.3 0.5 6.5 2.9 6.4 0.4 1.8 4.5 1.2 0.6 0.0 12.2 0.3 4.8 0.1 1.9 2.7 0.4 3.6 1.0 2.6 0.8 3.7 1.1 48.9 0.9 1.7 0.5 2.4 9.6 3.7 0.3 4.7 23.8 2.4 1.0 0.5 3.2 2.2 6.3 3.3 2.5 5.5 0.2 2.0 1.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 23.0 4.0 1.6 1.8 2.2 1.9 2.7 0.5 2.3 2.1 3.0 6.4 9.9 11.1 0.1 15.2 1.4 0.8 2.2 5.1 5.4 1.9 5.2 2.8 5.6 0.0 16.7 0.6 0.1 0.2 0.0 1.3 3.1 1.7 0.5 3.0 7.7 0.4 58.3 0.6 0.4 23.5 1.5 1.1 0.0 1.8 1.1 2.1 0.3 0.0 49.5 0.3 0.0 0.0 7.6 2.7 14.9 0.2 3.6 2.8 0.1 39.3 0.0 14.1 5.8 2.4 0.4 11.3 0.8 1.1 0.6 0.5 4.2 4.6 0.0 2.9 2.7 1.8 3.8 0.5 10.7 0.7 0.6 13.2 0.4 1.6 CEACAM16 DFNA4B ENSG00000213892 "CEA cell adhesion molecule 16, tectorial membrane component" Q2WEN9 19 44699151-44710718 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pancreas: 2.0" "Group enriched" "Detected in some" 7 "Bipolar cells: 7.7;Skeletal myocytes: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045075 Uncertain "Secreted in other tissues" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA045075: AB_10959617" "unprognostic (1.27e-1)" "unprognostic (3.73e-1)" "unprognostic (3.12e-1)" "unprognostic (3.32e-2)" "unprognostic (4.72e-1)" "unprognostic (1.42e-2)" "unprognostic (7.76e-2)" "unprognostic (3.59e-2)" "unprognostic (7.81e-3)" "unprognostic (3.88e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (7.94e-2)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 20.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 CER1 DAND4 ENSG00000147869 "Cerberus 1, DAN family BMP antagonist" O95813 9 14719724-14722733 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "epididymis: 1.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 82 "testis cancer: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEL: 4.0;NTERA-2: 7.0;SCLC-21H: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA019917 Uncertain "Secreted - unknown location" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" "HPA019917: AB_1846539" "unprognostic (2.98e-2)" "unprognostic (5.36e-2)" "unprognostic (5.99e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.1 0.3 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.3;testis: 19.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Fibroblasts: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 31.8;hTCEpi: 30.8;hTERT-HME1: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039902, HPA040005" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA039902: AB_10795236, HPA040005: AB_10795160" "unprognostic (4.92e-3)" "unprognostic (9.05e-2)" "unprognostic (7.99e-3)" "prognostic favorable (3.11e-4)" "unprognostic (5.58e-3)" "unprognostic (6.89e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (2.89e-1)" "unprognostic (2.34e-1)" "unprognostic (7.72e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "unprognostic (4.29e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" 1.1 0.8 1.6 0.3 2.4 0.1 1.3 1.3 1.7 3.5 13.2 0.2 0.1 1.9 4.7 0.3 22.3 1.2 1.3 2.4 3.9 2.7 1.4 3.0 0.6 5.5 6.6 2.2 1.7 2.9 6.5 0.9 3.6 0.7 0.1 4.6 1.1 1.6 0.3 1.5 0.2 0.6 2.7 1.7 0.4 19.9 4.1 0.5 4.7 0.4 0.9 0.3 1.3 1.6 4.7 0.4 0.4 0.2 0.5 0.5 0.5 0.3 2.5 1.2 3.0 0.3 1.4 0.2 3.7 0.2 0.7 0.9 0.3 31.8 4.4 0.2 0.5 0.2 0.6 0.3 3.7 0.1 8.6 1.8 30.8 2.4 19.9 0.7 1.3 0.5 7.5 0.1 1.9 0.9 0.3 0.6 0.4 0.4 0.2 0.4 0.8 0.0 5.4 0.5 2.5 0.1 0.2 0.1 0.2 0.8 0.9 0.1 1.0 2.5 3.9 0.5 0.5 0.5 0.2 3.8 2.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 1.6 2.4 1.3 1.7 2.4 3.9 5.5 6.6 3.6 2.7 4.1 1.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CHRNA1 CHRNA ENSG00000138435 "Cholinergic receptor nicotinic alpha 1 subunit" P02708 2 174747592-174787935 "Disease related genes, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 170.1" "Cell type enriched" "Detected in some" 48 "Skeletal myocytes: 193.5" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Group enriched" "Detected in some" 13 "cerebral cortex: 12.8;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "LHCN-M2: 445.4;RH-30: 360.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071554 Enhanced Supported "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA071554: AB_2686416" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.22e-3)" "unprognostic (2.28e-2)" "unprognostic (2.96e-1)" "unprognostic (8.55e-3)" "unprognostic (5.34e-2)" "unprognostic (5.29e-3)" "unprognostic (9.59e-2)" "unprognostic (9.64e-2)" "unprognostic (9.66e-2)" "unprognostic (6.37e-2)" "unprognostic (4.18e-4)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-2)" 0.2 0.0 0.2 0.2 0.4 0.0 0.5 0.1 12.8 0.6 0.2 1.5 0.2 0.0 0.2 0.6 0.0 0.0 0.3 5.5 0.2 0.0 0.2 0.6 0.8 0.5 0.2 0.0 0.0 0.0 3.3 0.2 0.5 2.0 0.9 0.0 3.2 0.0 170.1 0.5 0.0 0.0 0.3 0.0 0.0 0.4 0.3 1.1 0.0 20.4 1.2 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 21.5 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.2 445.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 360.2 0.0 0.0 0.3 2.9 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.1 12.8 5.5 0.2 0.5 0.2 0.5 0.3 0.3 0.7 0.1 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 4.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.0 0.6 0.4 1.7 0.3 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 193.5 0.3 0.1 0.2 0.0 0.0 0.0 1.8 0.0 0.2 0.0 CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573765-46598496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 35.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 45.4;monocytes: 55.5;Peritubular cells: 60.2;Sertoli cells: 52.6;Skeletal myocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.5" "Group enriched" "Detected in many" 10 "granulocytes: 10.9;monocytes: 10.2;T-cells: 18.5" "Cell line enhanced" "Detected in many" "EFO-21: 22.8;NTERA-2: 20.5;PC-3: 17.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 9800 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA003919: AB_10601258, HPA030503: " "unprognostic (3.16e-1)" "prognostic favorable (7.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (7.85e-2)" "unprognostic (9.82e-3)" "unprognostic (3.52e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-3)" "unprognostic (6.71e-2)" "unprognostic (1.19e-1)" "unprognostic (8.85e-3)" "unprognostic (8.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" 13.2 3.4 5.4 1.7 7.3 2.5 7.5 6.4 7.0 11.2 3.7 3.7 0.8 5.8 0.4 2.5 4.9 1.9 17.4 5.4 7.1 4.0 7.5 3.6 1.8 6.1 7.3 35.3 2.0 1.2 4.2 2.0 6.0 4.1 0.8 0.9 3.5 1.4 4.4 7.3 4.0 1.4 4.7 10.2 3.4 2.1 8.0 1.4 5.8 3.9 0.7 4.5 7.7 4.0 5.5 4.7 3.9 3.5 10.8 7.5 0.2 7.6 5.4 2.0 2.6 1.2 2.1 0.0 22.8 3.1 1.3 4.1 3.8 1.3 1.7 3.2 8.1 1.1 0.3 4.1 16.6 1.9 0.1 2.5 1.1 3.8 3.1 3.4 6.2 2.5 0.0 4.7 1.5 2.6 0.7 2.4 20.5 0.4 17.0 3.6 3.2 10.3 5.5 0.2 8.8 3.4 1.1 0.2 0.9 9.6 1.3 0.4 1.4 6.1 0.6 3.3 3.5 11.0 2.4 1.7 6.8 0.1 0.4 2.4 2.2 0.7 1.5 7.1 1.4 1.2 5.8 2.8 1.2 0.6 1.2 1.1 10.9 0.6 10.2 0.8 18.5 1.9 5.4 7.3 6.4 7.0 5.4 7.1 6.1 7.3 6.0 4.7 8.0 4.0 33.8 0.0 3.1 22.9 2.5 12.4 2.0 4.8 1.2 0.8 2.2 3.7 7.4 10.0 2.6 1.8 0.0 5.3 11.5 1.7 1.9 2.8 0.0 3.6 20.8 16.3 0.0 0.0 0.9 2.5 4.3 23.6 0.0 1.6 0.0 19.7 15.7 4.5 11.5 3.3 4.1 2.9 0.0 14.2 45.4 0.3 19.0 14.1 14.2 4.7 55.5 5.2 4.1 13.0 1.0 1.8 1.5 60.2 4.7 6.7 0.7 2.1 1.9 0.8 52.6 43.1 11.2 0.5 1.3 1.3 13.2 1.4 9.9 11.4 0.9 3.3 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 23.7;kidney: 46.2;liver: 16.9" "Cell type enriched" "Detected in many" 4 "Skeletal myocytes: 214.4" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in all" 4 "CACO-2: 49.0;RH-30: 66.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: AB_1078531, HPA003213: AB_2666843" "unprognostic (3.33e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (7.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.20e-4)" "unprognostic (3.59e-2)" "prognostic favorable (2.05e-8)" "unprognostic (7.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" 2.1 2.5 1.7 1.7 1.9 1.5 1.6 3.8 1.6 1.8 2.5 2.4 4.9 4.0 23.7 2.4 3.0 3.9 1.3 1.5 2.9 46.2 16.9 2.8 1.3 3.2 3.2 7.0 2.1 1.4 2.3 5.8 3.7 1.7 2.8 3.4 2.5 1.0 4.0 4.8 3.8 2.9 2.5 1.8 2.9 2.1 2.7 1.1 2.2 2.8 1.2 1.4 2.0 2.3 2.9 5.4 4.2 5.5 12.8 7.5 7.9 2.8 1.2 1.6 1.9 49.0 3.0 3.5 1.2 2.5 9.7 2.8 9.9 1.7 2.2 1.1 7.5 3.3 2.7 12.8 7.2 4.1 5.7 4.9 1.6 3.7 5.9 1.2 5.8 4.0 4.3 4.7 5.3 3.2 1.6 1.4 5.7 7.4 2.4 1.9 66.0 5.2 6.0 5.5 7.2 5.2 3.3 3.0 5.1 14.1 3.0 2.1 3.8 1.6 3.7 12.7 1.4 3.6 11.9 7.3 2.8 6.6 8.5 0.0 0.9 0.0 0.1 0.9 0.1 0.1 0.2 0.2 2.6 0.1 0.0 0.0 0.2 0.1 0.1 2.8 0.0 0.3 1.7 1.9 3.8 1.6 1.5 2.9 3.2 3.2 3.7 2.5 2.7 2.3 4.3 9.6 8.4 20.5 2.1 7.1 1.8 1.6 5.2 27.4 1.8 1.4 1.9 2.8 2.3 12.9 2.1 6.2 17.7 11.3 11.7 4.1 2.0 8.0 10.0 5.5 0.0 3.4 11.5 3.5 2.6 7.9 8.6 22.8 2.5 0.8 1.4 35.2 11.1 8.4 15.6 6.6 4.1 17.6 19.8 0.6 5.3 10.9 3.6 46.9 10.1 2.7 2.1 20.6 9.6 7.7 7.3 13.2 2.2 4.0 20.4 38.8 4.2 4.3 0.0 214.4 4.8 0.9 2.3 8.1 9.5 5.1 1.9 9.3 7.0 4.8 CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 420.3" "Cell type enhanced" "Detected in some" "Adipocytes: 76.3;Endothelial cells: 27.9;Fibroblasts: 126.4;Hepatic stellate cells: 57.5;Leydig cells: 30.1;Microglial cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 297.9;ASC TERT1: 591.9;U-2197: 120.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" NA NA 6540000000 25000000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" 420.3 51.0 44.4 9.3 46.4 1.7 214.8 45.5 66.6 89.4 50.9 83.9 31.6 60.4 17.1 49.9 41.1 35.6 259.9 43.0 42.9 131.4 29.0 201.2 33.1 51.3 56.1 26.0 14.6 14.3 27.7 142.8 48.0 33.5 37.4 0.7 49.8 19.1 74.8 149.7 78.2 25.5 44.8 264.5 43.5 113.2 50.7 10.1 88.4 68.0 8.2 100.9 74.9 43.0 0.0 0.0 0.1 0.2 297.9 591.9 0.0 40.1 62.9 1.2 6.2 0.0 0.0 0.1 0.1 3.1 0.0 0.1 0.0 0.1 0.1 0.3 0.9 0.6 0.1 0.1 0.5 0.1 0.7 47.5 0.1 0.3 0.1 0.4 0.5 0.3 0.0 1.7 0.5 0.2 0.0 2.2 0.0 0.0 0.6 0.0 0.1 2.2 0.0 0.0 0.3 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 4.5 0.2 120.6 0.1 1.0 1.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.4 46.4 45.5 66.6 43.0 42.9 51.3 56.1 48.0 44.8 50.7 43.0 76.3 0.0 0.0 1.6 0.3 3.4 0.0 0.0 1.8 0.0 0.7 0.3 0.8 1.5 0.0 0.0 0.0 0.0 0.5 0.0 3.9 0.0 4.0 0.3 16.9 27.9 0.0 2.7 0.8 0.2 0.0 126.4 3.1 0.3 0.0 0.0 57.5 0.3 0.9 0.0 0.6 0.0 0.0 1.2 9.5 19.5 30.1 2.2 3.6 69.3 0.7 0.4 0.0 1.5 0.7 0.1 0.0 6.4 0.5 0.0 0.0 0.0 0.0 0.3 0.0 1.0 12.3 0.0 0.0 0.7 3.8 0.1 0.7 0.4 0.0 0.0 COG8 "DOR1, FLJ22315" ENSG00000213380 "Component of oligomeric golgi complex 8" Q96MW5 16 69320140-69339583 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041406, HPA049429" Approved Supported "Golgi apparatus" No No "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA041406: AB_2677459, HPA049429: AB_2680763" "unprognostic (4.02e-2)" "unprognostic (6.46e-2)" "unprognostic (2.90e-1)" "unprognostic (1.19e-2)" "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (4.35e-2)" "unprognostic (1.11e-1)" "unprognostic (2.02e-1)" "prognostic favorable (3.12e-5)" "unprognostic (3.10e-1)" "prognostic favorable (2.47e-7)" "unprognostic (4.73e-2)" "unprognostic (2.58e-1)" "unprognostic (7.83e-2)" "unprognostic (1.35e-2)" 9.9 14.5 19.7 8.5 23.2 6.5 11.1 23.2 24.4 9.8 24.0 10.5 10.5 10.8 14.1 9.9 13.9 7.7 11.2 19.4 19.7 13.4 15.0 10.2 11.3 21.1 20.6 13.7 14.2 19.9 12.0 7.9 21.2 10.3 9.9 7.7 13.8 10.6 18.1 16.3 10.0 10.5 20.3 10.9 11.2 20.3 20.9 12.2 13.0 15.8 11.3 9.4 7.7 28.1 13.2 28.5 18.2 26.7 30.1 21.0 19.4 16.9 18.6 23.0 18.7 26.2 19.8 23.7 18.1 23.0 12.4 24.9 29.5 24.3 19.8 11.9 26.4 17.0 19.9 35.0 21.3 21.1 14.8 25.2 23.5 25.2 14.7 22.2 22.6 20.4 35.4 5.7 16.7 38.3 19.4 31.3 32.2 17.8 20.5 35.6 12.6 33.3 23.6 11.1 26.0 31.1 37.5 15.0 17.5 18.4 35.4 17.8 20.5 16.8 14.4 15.8 14.1 31.3 27.1 36.8 17.3 18.8 19.2 41.4 19.6 20.6 17.8 19.0 19.6 13.3 19.2 18.2 18.6 19.0 17.4 16.7 15.6 22.2 17.6 10.7 19.6 16.8 19.7 23.2 23.2 24.4 19.4 19.7 21.1 20.6 21.2 20.3 20.9 28.1 3.2 9.6 9.7 1.3 9.4 4.2 10.4 5.8 5.2 18.9 7.3 6.7 0.0 24.3 10.6 11.0 18.8 15.0 5.0 12.6 1.9 7.6 17.4 6.1 6.4 7.2 12.7 5.5 1.9 8.0 9.1 7.4 7.1 4.6 7.0 9.0 15.7 28.5 9.5 11.8 2.0 11.7 20.3 7.9 3.3 4.8 12.8 3.1 5.4 1.0 8.4 12.1 10.3 2.0 2.6 5.4 9.5 15.8 9.0 9.6 19.3 15.3 10.2 19.9 13.1 15.5 6.2 9.9 13.6 7.2 4.1 9.2 8.3 5.4 16.7 7.2 COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.5;choroid plexus: 39.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 26.6;Inhibitory neurons: 6.3;Microglial cells: 8.4;Oligodendrocytes: 27.9" "Cancer enhanced" "Detected in many" "breast cancer: 42.8;pancreatic cancer: 51.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTEC/SVTERT24-B: 39.7" "Low region specificity" "Detected in many" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA053268: " "unprognostic (3.83e-2)" "unprognostic (6.81e-2)" "unprognostic (7.20e-2)" "unprognostic (7.45e-3)" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (3.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" "unprognostic (4.37e-2)" "unprognostic (7.03e-2)" "unprognostic (1.38e-11)" "unprognostic (2.16e-3)" "unprognostic (7.22e-2)" "unprognostic (3.60e-1)" "unprognostic (2.06e-3)" 0.3 0.0 2.2 0.2 8.6 0.3 0.3 4.6 4.5 1.2 39.9 0.2 0.0 0.3 0.0 0.0 0.0 8.9 0.3 1.3 3.3 0.4 0.2 2.8 0.6 7.7 5.6 3.9 3.3 2.5 0.4 0.1 7.1 1.9 0.1 0.9 2.6 0.8 0.1 0.4 0.1 0.5 4.3 2.5 0.1 0.2 6.3 0.1 0.7 0.0 1.9 0.2 0.1 15.5 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.2 2.9 0.4 6.0 0.1 0.0 0.1 0.0 1.0 0.0 0.7 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.0 39.7 0.0 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 6.3 0.1 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 8.6 4.6 4.5 1.3 3.3 7.7 5.6 7.1 4.3 6.3 15.5 2.6 0.0 0.6 3.9 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.1 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.4 26.6 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.4 0.0 2.2 0.0 2.5 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.2 5.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial stromal cells: 44.3;Excitatory neurons: 52.9;Fibroblasts: 99.7;Leydig cells: 60.3;Sertoli cells: 46.0;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "fHDF/TERT166: 1432.1;SiHa: 846.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 29.1" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 9100000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" 105.1 15.7 2.2 16.0 1.9 0.0 65.4 0.8 2.7 112.8 0.4 74.9 8.7 124.5 5.5 36.2 42.2 20.9 25.5 1.0 1.2 25.9 3.5 24.6 7.2 1.8 4.8 123.2 5.9 5.0 4.8 1.8 0.6 20.8 17.2 0.4 16.1 42.4 14.4 48.9 40.6 72.1 0.6 11.4 18.1 4.6 2.0 5.5 19.3 12.5 4.2 26.3 45.8 0.8 0.2 2.2 11.5 0.2 270.2 162.0 28.3 275.4 229.3 186.2 257.3 27.5 0.7 0.0 27.7 1432.1 3.9 59.2 0.5 28.7 174.6 0.2 1.4 0.2 101.1 0.1 97.9 0.3 0.2 234.9 5.0 42.2 50.6 173.6 32.0 0.1 0.0 0.0 29.4 0.2 0.1 0.2 6.4 0.0 15.3 0.1 23.1 0.2 8.9 14.4 0.0 0.0 846.1 21.2 0.3 15.5 131.8 0.5 0.2 78.5 97.0 41.5 91.4 0.1 0.1 0.4 26.4 0.3 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.8 2.7 1.0 1.2 1.8 4.8 0.6 0.6 2.0 0.8 14.2 76.9 5.1 2.3 0.0 20.6 0.6 12.7 5.2 0.4 4.7 7.1 4.1 0.0 4.7 3.7 0.0 0.6 0.0 0.0 0.0 1.4 24.1 6.3 44.3 11.0 0.0 0.0 52.9 4.6 1.3 99.7 2.6 14.1 1.3 0.1 3.3 0.0 0.8 0.0 32.4 0.0 0.0 0.3 18.4 14.7 60.3 1.8 21.4 38.4 0.0 0.0 0.0 19.6 1.2 6.7 0.0 13.2 0.1 1.7 0.0 0.9 1.7 0.0 46.0 20.0 48.6 0.3 0.6 0.6 13.1 0.7 2.5 1.4 0.1 0.3 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 122.0;Peritubular cells: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 133.1;ASC TERT1: 102.9;BJ hTERT+: 115.9;fHDF/TERT166: 106.5;HSkMC: 98.7;U-2197: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027237 Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA027237: AB_10600699" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" 33.6 17.3 19.0 14.4 44.7 0.3 41.0 35.9 32.4 169.7 7.6 78.9 14.8 93.6 23.7 22.4 37.4 39.4 33.6 18.9 29.8 11.5 3.2 31.1 8.5 55.5 43.2 177.9 7.8 3.5 28.6 21.1 48.6 102.8 10.9 8.8 35.5 91.3 8.4 69.3 35.8 56.2 34.0 9.9 42.1 40.9 40.3 5.6 46.8 7.4 4.1 106.9 86.8 57.5 0.1 2.0 0.0 0.1 133.1 102.9 14.6 60.5 115.9 15.1 16.1 0.4 11.0 0.0 1.9 106.5 2.3 48.3 0.0 65.8 3.5 0.0 0.2 0.0 8.1 21.3 45.1 0.0 0.3 98.7 44.6 43.2 22.7 3.8 0.1 0.3 0.0 0.2 2.1 0.0 0.1 0.5 0.1 0.4 0.2 0.2 1.3 0.4 0.0 0.4 1.5 2.7 7.3 1.2 9.6 0.5 1.2 0.0 0.2 52.3 52.5 92.1 1.3 0.1 0.2 0.0 36.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 44.7 35.9 32.4 18.9 29.8 55.5 43.2 48.6 34.0 40.3 57.5 4.3 9.6 3.9 109.0 0.1 30.7 14.8 37.5 15.9 2.4 7.9 21.3 8.4 0.0 9.8 18.4 2.1 1.9 0.6 2.0 0.0 4.6 13.6 2.6 11.5 2.8 27.6 0.4 23.9 0.7 3.8 54.3 8.2 2.4 7.0 0.2 5.0 0.0 1.3 0.0 8.2 30.9 8.2 0.6 11.4 26.8 43.8 0.7 14.2 10.3 0.0 31.3 0.0 62.4 122.0 1.2 4.7 91.4 0.3 9.3 16.8 2.1 15.0 2.5 0.0 5.4 25.0 14.9 3.8 1.9 21.2 2.2 2.2 0.5 6.8 15.3 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL6A6 ENSG00000206384 "Collagen type VI alpha 6 chain" A6NMZ7 3 130560334-130678155 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "parathyroid gland: 97.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Fibroblasts: 20.6;Inhibitory neurons: 5.3;Oligodendrocytes: 4.6;Skeletal myocytes: 3.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SuSa: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "spinal cord: 10.0" HPA045239 Uncertain "Secreted to extracellular matrix" NA NA 700000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA045239: AB_2679268" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (9.91e-2)" "unprognostic (2.08e-4)" "unprognostic (2.79e-1)" "unprognostic (1.11e-5)" "unprognostic (3.74e-3)" "unprognostic (5.59e-2)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (8.90e-2)" "unprognostic (2.70e-1)" "unprognostic (2.96e-4)" "unprognostic (5.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (1.07e-1)" 1.8 0.0 0.0 0.0 0.2 0.2 2.5 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.3 0.9 0.3 0.1 3.3 0.0 0.0 0.0 0.8 7.3 0.0 0.0 0.0 0.2 0.0 97.8 3.6 0.7 0.0 0.0 0.0 0.3 1.5 0.0 0.1 0.4 0.0 0.5 0.0 1.2 0.1 0.4 0.1 1.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 1.1 1.3 0.0 0.9 0.0 0.0 0.0 1.1 0.2 0.4 2.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 2.9 0.1 0.0 0.0 4.6 0.0 0.0 20.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 0.0 0.0 0.0 1.5 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 3.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 3.3 0.8 0.0 0.4 0.0 0.9 0.1 0.2 0.0 0.0 0.0 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 77.6;heart muscle: 65.3;skin 1: 80.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 19.3;Early spermatids: 37.0;Fibroblasts: 32.0;Glandular and luminal cells: 32.0;Late spermatids: 75.3;Spermatocytes: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 859.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA077555: " "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (9.08e-5)" "prognostic unfavorable (2.04e-4)" "unprognostic (8.05e-2)" "unprognostic (8.45e-2)" "unprognostic (3.62e-2)" "unprognostic (5.12e-2)" "unprognostic (1.65e-1)" "unprognostic (1.55e-2)" "unprognostic (2.18e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (1.52e-6)" "unprognostic (5.96e-3)" "unprognostic (1.44e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (6.95e-4)" 77.6 0.2 0.0 1.1 0.2 0.0 11.0 1.3 0.2 7.5 0.0 2.3 0.0 4.6 7.6 9.5 1.2 16.1 65.3 0.0 0.0 5.2 0.3 8.0 3.6 0.3 0.1 0.4 2.8 2.2 0.4 8.2 0.1 10.2 0.0 0.0 14.1 6.7 18.0 80.6 0.9 12.1 0.3 0.3 2.5 14.9 0.0 0.1 10.3 0.6 0.3 6.5 22.7 0.1 0.0 0.0 0.0 0.0 178.4 0.4 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 859.6 0.0 0.2 1.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.3 0.0 0.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.2 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 3.2 0.5 0.0 0.0 11.5 0.6 19.3 0.0 1.4 0.3 0.3 0.8 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 37.0 2.8 3.7 1.0 0.0 0.0 0.1 0.2 0.2 32.0 0.0 32.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 1.3 0.0 0.0 10.7 75.3 0.9 0.7 10.6 0.0 0.1 1.6 0.0 0.0 0.1 0.2 0.0 0.7 0.0 0.3 0.0 0.0 0.7 0.4 6.6 2.4 4.2 16.8 1.6 0.0 7.1 0.5 1.0 0.0 0.2 0.3 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 CPSF4L ENSG00000187959 "Cleavage and polyadenylation specific factor 4 like" A6NMK7 17 73248449-73262352 "Predicted intracellular proteins" RNA-binding "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Skeletal myocytes: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 3.0" "Region enriched" "Detected in single" 36 "cerebellum: 10.2" "Low region specificity" "Detected in many" HPA044047 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "HPA044047: AB_10961638" "unprognostic (7.30e-2)" "unprognostic (1.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" "unprognostic (1.99e-1)" "unprognostic (7.73e-2)" "unprognostic (2.32e-2)" "unprognostic (5.59e-2)" "unprognostic (6.57e-3)" "unprognostic (9.76e-2)" "unprognostic (1.83e-1)" "unprognostic (3.66e-2)" "unprognostic (9.03e-8)" "unprognostic (6.71e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-2)" "unprognostic (7.44e-3)" 0.1 0.1 0.1 0.0 0.1 0.0 0.4 0.9 0.5 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.9 0.5 0.2 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 144.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.5;Fibroblasts: 8.5;Microglial cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 73.6;BJ: 39.7;BJ hTERT+: 51.7;hTERT-RPE1: 30.6;RH-30: 57.6;U-2197: 46.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" 11.1 1.8 0.3 2.7 1.0 0.0 11.8 0.5 2.9 33.3 2.3 4.6 0.8 14.6 9.1 7.4 19.9 30.7 2.8 0.8 0.4 2.0 1.4 7.1 2.8 0.7 0.5 144.3 3.2 1.8 5.2 42.1 0.8 5.9 1.8 0.1 1.5 24.2 0.2 13.8 2.6 8.4 1.2 1.4 3.3 3.1 0.3 1.5 7.8 0.0 1.0 23.0 25.1 0.9 26.1 0.4 0.0 1.6 5.0 0.5 73.6 39.7 51.7 14.5 5.8 1.7 0.7 0.0 3.7 21.3 0.3 0.0 0.0 0.0 5.4 0.0 2.9 0.0 0.3 0.7 4.4 0.0 0.0 9.2 0.0 0.0 0.0 30.6 0.0 0.0 1.2 0.0 0.9 6.1 0.0 0.1 9.2 0.2 22.0 0.1 57.6 0.0 0.0 1.1 0.1 0.1 1.4 0.5 0.1 8.3 0.3 0.0 0.0 2.0 2.6 46.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.5 2.9 0.8 0.4 0.7 0.5 0.8 1.2 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.0 0.6 8.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CRLF1 "CISS, CISS1, CLF, CLF-1" ENSG00000006016 "Cytokine receptor like factor 1" O75462 19 18572220-18607741 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 88.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Basal keratinocytes: 9.7;Fibroblasts: 16.0;Respiratory ciliated cells: 11.9;Skeletal myocytes: 19.9;Smooth muscle cells: 10.5" "Group enriched" "Detected in all" 4 "lung cancer: 27.4;thyroid cancer: 36.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "ASC diff: 1048.7;Hep G2: 458.8" "Region enriched" "Detected in many" 7 "hippocampal formation: 21.1" "Group enriched" "Detected in some" 6 "cerebellum: 2.3;spinal cord: 8.6" "HPA041493, HPA041793" Approved "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041493: AB_10795637, HPA041793: AB_10804117" "unprognostic (1.97e-1)" "unprognostic (2.29e-1)" "unprognostic (2.34e-3)" "unprognostic (9.31e-3)" "unprognostic (1.58e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (4.95e-2)" "unprognostic (7.92e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (5.27e-3)" 40.1 14.5 18.7 0.9 24.6 0.0 18.7 22.4 51.7 25.7 11.2 8.9 0.5 12.8 0.9 17.4 11.3 1.4 88.5 22.0 13.5 7.7 1.5 16.0 0.4 24.3 28.0 4.5 8.9 0.5 8.9 11.3 17.8 8.9 0.4 0.1 14.9 6.2 21.4 27.3 5.0 1.5 18.7 2.4 7.5 1.3 13.4 0.3 50.3 0.9 0.2 9.3 15.5 25.5 0.0 0.0 0.0 10.7 1048.7 15.3 5.2 5.4 0.0 0.0 0.0 0.1 0.0 0.0 66.5 33.2 1.9 0.4 10.8 0.2 0.0 0.0 1.4 0.0 18.1 458.8 7.5 0.1 0.5 12.0 1.0 0.2 0.3 1.6 0.3 0.0 0.1 0.2 0.3 16.6 0.0 0.0 1.2 0.1 0.3 0.0 9.1 0.1 0.0 0.5 0.0 0.1 14.2 0.0 0.0 2.0 13.0 0.6 1.3 0.1 11.1 0.8 0.4 0.1 0.0 0.5 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 24.6 22.4 51.7 22.0 13.5 24.3 28.0 17.8 18.7 13.4 25.5 0.4 0.0 0.0 15.3 0.3 9.7 0.6 6.8 0.0 0.2 0.7 4.2 2.5 0.0 2.6 0.0 0.0 0.1 0.3 0.1 5.9 0.3 6.9 2.6 1.9 0.5 0.0 0.0 7.8 0.2 1.3 16.0 0.5 0.5 0.0 0.2 0.4 0.1 0.3 0.0 1.0 0.0 2.0 0.0 1.0 0.4 0.0 0.4 0.0 0.0 0.1 0.9 1.0 0.5 0.8 0.2 0.0 0.0 0.0 0.3 0.0 0.3 11.9 1.3 0.0 19.9 10.5 0.2 2.2 0.6 4.5 0.3 0.6 0.2 0.1 0.3 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155921580-155953912 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1;HSkMC: 44.6;Karpas-707: 85.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" NA NA 25000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" 19.1 31.5 8.0 17.8 8.0 5.0 31.9 6.2 11.8 36.7 7.9 19.6 32.8 37.2 36.1 16.7 36.9 40.7 20.2 7.8 7.6 34.5 98.8 36.8 24.5 7.1 7.5 28.0 19.9 24.5 9.6 41.2 6.9 29.8 23.2 5.2 22.1 32.2 6.7 10.0 34.0 30.7 7.0 39.7 15.5 9.4 7.4 14.1 34.5 17.8 17.9 28.0 15.4 7.6 0.8 0.6 4.1 3.7 17.3 37.1 0.2 1.6 18.3 3.3 5.7 0.4 14.4 0.2 1.2 6.8 1.2 0.1 0.2 0.1 2.6 1.6 0.1 0.4 0.5 0.2 18.1 1.4 0.2 44.6 3.5 2.2 1.8 25.6 3.5 0.7 0.3 85.8 11.7 0.7 1.1 0.4 0.7 0.6 0.7 4.8 0.5 1.0 16.8 7.5 0.5 4.3 2.4 9.3 2.3 2.0 4.2 2.6 3.0 13.3 0.7 0.4 2.3 8.3 0.2 0.2 24.4 0.3 18.6 5.3 0.9 0.6 1.2 0.7 3.0 1.2 1.4 0.8 0.4 1.5 1.6 2.0 0.7 3.0 0.9 1.0 3.3 1.4 8.0 8.0 6.2 11.8 7.8 7.6 7.1 7.5 6.9 7.0 7.4 7.6 29.3 38.5 20.8 15.0 19.9 10.5 13.1 11.3 12.0 10.4 20.1 13.0 5.0 44.3 14.3 25.8 2.1 20.5 19.6 15.6 13.7 24.6 0.4 20.9 34.6 28.2 6.7 8.6 1.7 20.7 7.7 51.5 8.6 27.3 8.8 25.0 43.2 58.1 16.3 5.0 1.7 7.9 8.2 29.2 23.7 1.5 30.4 21.4 30.2 7.5 26.5 17.0 22.6 36.7 5.4 12.7 6.3 25.2 7.0 17.5 21.1 10.7 14.5 1.9 19.7 34.0 24.6 0.3 2.1 5.9 9.1 10.5 14.5 14.3 6.6 9.5 CUTC CGI-32 ENSG00000119929 "CutC copper transporter" Q9NTM9 10 99702558-99756134 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 385.5;tongue: 204.2" "Cell type enriched" "Detected in all" 4 "Spermatocytes: 163.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038619, HPA058231" Enhanced Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" Nucleoli "HPA038619: AB_10672649, HPA058231: " "unprognostic (1.25e-2)" "unprognostic (5.92e-2)" "unprognostic (2.70e-1)" "unprognostic (8.66e-2)" "unprognostic (7.39e-2)" "unprognostic (1.39e-1)" "unprognostic (3.55e-3)" "unprognostic (8.67e-2)" "unprognostic (5.36e-2)" "unprognostic (1.81e-1)" "unprognostic (5.87e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.81e-7)" "unprognostic (1.00e-1)" "unprognostic (3.42e-2)" "unprognostic (2.41e-1)" "unprognostic (3.97e-1)" 38.7 15.5 19.3 14.6 21.9 23.6 27.3 20.8 25.9 17.3 17.3 19.4 11.1 14.7 11.0 16.0 17.1 12.1 41.7 18.7 20.7 13.5 30.2 15.1 22.3 21.0 20.6 12.6 14.2 8.6 7.8 11.3 21.3 16.1 15.9 28.3 16.9 11.2 385.5 18.6 20.9 14.4 20.1 28.6 18.6 43.4 20.3 23.9 13.2 204.2 19.7 43.8 16.7 25.0 27.4 57.7 19.9 60.7 71.8 32.8 10.8 22.0 28.0 21.6 24.2 26.7 20.5 98.9 19.1 37.5 10.6 22.9 40.8 36.6 23.9 29.5 39.0 32.9 26.1 42.7 33.2 61.5 15.5 34.0 22.3 34.5 71.1 26.8 37.8 56.2 29.6 21.4 16.4 19.4 55.7 63.2 20.0 27.7 21.4 37.5 23.3 38.3 22.8 11.2 6.5 14.8 10.1 15.9 28.9 27.1 25.3 34.7 21.2 9.0 12.2 9.9 29.5 34.7 48.5 69.6 29.4 130.0 8.2 70.6 42.6 111.7 56.9 35.2 60.0 73.4 53.9 54.9 47.1 66.5 74.4 57.2 68.6 63.1 46.0 54.2 57.0 45.3 19.3 21.9 20.8 25.9 18.7 20.7 21.0 20.6 21.3 20.1 20.3 25.0 26.3 9.6 12.5 15.3 32.8 12.1 14.7 23.1 5.7 18.7 12.6 15.2 40.6 14.3 14.9 5.5 8.4 18.6 23.2 4.6 21.5 16.9 12.6 11.4 12.0 19.8 12.1 28.2 8.5 17.4 13.5 32.8 10.7 8.3 30.4 14.4 27.5 23.4 20.9 11.8 9.0 7.4 12.2 17.0 11.7 10.8 13.1 16.6 30.2 7.5 28.0 25.9 21.6 8.0 26.9 10.5 7.4 16.1 27.2 16.1 19.2 34.8 21.5 33.0 19.7 27.1 15.5 163.3 36.7 14.3 10.9 13.5 25.6 36.3 9.6 11.6 CWC22 "EIF4GL, fSAPb, KIAA1604, NCM" ENSG00000163510 "CWC22 spliceosome associated protein homolog" Q9HCG8 2 179944876-180007297 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036748 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA036748: AB_10669913" "unprognostic (1.90e-1)" "unprognostic (7.10e-2)" "unprognostic (7.30e-2)" "unprognostic (6.14e-2)" "unprognostic (4.96e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (3.15e-1)" "unprognostic (1.31e-2)" "unprognostic (3.30e-2)" "unprognostic (3.84e-2)" "unprognostic (4.80e-2)" "prognostic unfavorable (7.76e-5)" "unprognostic (1.74e-1)" "unprognostic (3.03e-2)" "unprognostic (1.41e-1)" "unprognostic (9.44e-3)" 12.7 10.2 7.1 13.1 7.8 16.0 15.0 13.5 10.1 14.1 7.1 11.9 10.1 16.9 10.4 12.5 12.0 12.1 10.1 7.6 7.2 13.4 16.8 11.5 18.5 6.4 6.9 19.3 9.2 13.5 8.2 14.5 7.0 12.5 11.8 12.4 10.2 10.9 13.6 11.0 10.4 13.9 7.1 14.7 11.0 9.0 7.0 21.8 16.0 14.5 18.2 14.1 12.1 8.9 19.1 11.2 31.6 21.1 22.7 26.7 24.1 24.5 28.7 29.4 28.7 25.9 23.1 36.7 21.6 17.9 25.6 20.5 30.4 23.1 44.2 33.0 26.2 49.1 15.1 35.4 22.0 69.6 26.2 17.5 27.1 37.4 49.8 19.3 22.3 25.2 54.6 21.9 19.7 18.9 36.5 34.7 48.8 22.5 18.3 32.8 38.9 27.7 20.2 23.5 21.6 28.8 20.3 15.9 28.5 33.8 11.8 42.2 19.0 25.1 21.2 16.8 25.7 19.2 21.5 44.3 22.6 27.2 26.1 49.7 13.3 31.4 16.1 16.7 16.3 17.4 17.3 19.5 13.9 14.5 21.1 16.7 22.0 16.0 13.3 8.6 16.5 11.5 7.1 7.8 13.5 10.1 7.6 7.2 6.4 6.9 7.0 7.1 7.0 8.9 38.0 19.2 33.8 20.5 38.0 19.1 29.2 16.9 22.2 19.5 12.9 19.8 26.6 22.8 27.0 11.0 25.0 18.3 36.5 11.8 9.8 23.4 1.6 24.2 31.9 27.2 15.6 14.9 35.8 19.1 17.5 32.5 19.9 25.1 27.3 24.7 16.8 12.8 13.7 13.5 28.4 16.4 14.2 20.6 12.1 2.4 23.3 24.2 3.6 15.0 31.6 17.3 30.9 35.2 35.1 18.7 17.6 18.4 20.8 16.8 15.7 20.3 34.4 19.1 46.0 40.3 25.1 22.8 21.3 14.1 18.6 24.8 32.5 18.6 15.6 19.5 CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 347.2;Distal tubular cells: 172.1;Fibroblasts: 566.4;Kupffer cells: 191.8;Smooth muscle cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 509.6;BJ hTERT+: 303.5;BJ hTERT+ SV40 Large T+: 294.9;BJ hTERT+ SV40 Large T+ RasG12V: 441.2;fHDF/TERT166: 501.8;HSkMC: 1293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" 366.8 82.6 19.4 143.8 20.2 35.1 237.4 19.1 28.1 268.4 24.5 124.3 53.6 360.7 54.3 138.5 122.1 263.3 190.3 19.4 18.6 124.8 252.8 71.0 215.8 22.3 21.1 112.3 131.2 126.7 21.3 8.5 19.1 47.8 115.5 2.1 116.3 66.2 158.9 99.4 96.5 343.5 19.9 356.6 45.4 19.4 21.0 142.6 103.4 181.3 119.7 107.0 174.3 17.7 0.0 0.0 0.4 0.6 509.6 78.9 0.4 187.7 303.5 294.9 441.2 0.0 0.1 0.2 1.9 501.8 0.0 0.1 0.8 0.2 97.1 187.2 2.4 0.0 0.0 0.0 172.8 0.4 0.9 1293.8 0.0 63.8 0.1 0.0 0.2 0.1 0.1 0.0 1.0 0.4 0.7 0.6 32.2 0.0 0.6 0.8 0.3 224.3 0.2 0.0 0.6 0.6 0.3 0.7 0.0 63.6 272.2 0.4 0.4 0.4 0.5 205.0 0.2 0.2 0.1 0.1 0.6 0.3 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 20.2 19.1 28.1 19.4 18.6 22.3 21.1 19.1 19.9 21.0 17.7 347.2 0.0 1.1 1.3 1.4 76.3 0.3 0.0 9.6 1.5 8.1 14.0 25.0 10.0 0.6 5.5 0.0 0.3 2.1 0.0 172.1 0.8 2.2 1.7 46.8 134.1 0.0 0.0 0.6 20.5 0.3 566.4 1.5 1.0 0.0 0.4 55.6 2.5 2.6 0.0 6.6 3.9 0.0 191.8 110.1 3.7 70.2 27.9 135.2 74.0 0.0 1.9 0.0 12.1 0.1 3.0 0.0 8.6 1.0 1.0 0.1 25.5 0.0 0.8 85.5 43.7 146.1 1.8 5.9 6.3 62.7 0.7 9.6 33.2 0.5 0.5 CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 94.3;Fibroblasts: 87.6;Leydig cells: 95.7;Melanocytes: 78.2;Sertoli cells: 92.1;Smooth muscle cells: 95.6" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 79.6;Hep G2: 61.7;HHSteC: 120.7;HSkMC: 95.4;SH-SY5Y: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" 79.6 20.8 10.1 12.0 10.7 1.7 55.1 20.6 13.6 27.7 14.1 27.1 21.1 19.6 4.6 12.8 20.4 13.2 104.4 9.5 15.8 12.4 19.0 27.8 7.2 17.5 26.0 13.8 12.8 11.7 10.9 8.9 26.8 29.9 9.3 77.6 14.2 11.0 19.3 19.5 26.6 5.9 10.1 12.2 22.9 5.3 14.3 5.3 50.1 9.6 2.6 50.7 25.6 9.8 0.2 1.1 1.8 0.4 79.6 23.1 26.1 0.7 2.0 0.3 0.9 0.0 0.3 0.2 24.1 2.4 0.3 0.7 0.1 33.7 0.1 0.1 0.2 0.4 0.4 61.7 120.7 0.0 0.0 95.4 7.2 2.5 2.5 0.4 0.3 0.8 0.3 0.1 1.2 0.8 0.2 0.4 0.3 0.0 1.4 0.5 0.3 0.2 0.4 0.1 0.6 129.8 0.1 0.0 2.7 5.9 0.2 0.6 0.2 3.1 1.6 0.3 0.0 1.2 0.3 0.3 0.2 0.3 9.9 0.0 0.1 0.1 0.2 0.1 0.1 1.6 0.1 0.0 0.1 2.2 0.2 0.5 0.9 1.0 0.0 0.0 0.2 0.2 10.1 10.7 20.6 13.6 9.5 15.8 17.5 26.0 26.8 10.1 14.3 9.8 94.3 3.2 2.0 2.0 3.5 10.8 1.3 17.3 3.4 38.5 1.4 5.7 6.1 0.0 6.7 0.0 0.0 1.4 1.9 0.1 0.0 0.8 0.7 2.9 4.2 23.1 0.0 0.0 2.4 0.2 0.6 87.6 1.5 0.7 0.0 0.2 2.2 1.2 0.4 8.4 12.3 0.0 0.0 0.0 13.3 2.5 95.7 2.6 78.2 3.7 0.0 22.1 0.0 1.0 1.0 0.1 0.0 23.3 0.6 0.8 0.0 0.2 21.1 12.9 92.1 21.8 95.6 1.6 1.4 0.7 6.7 2.9 2.6 9.2 0.0 1.0 CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 84.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.2;Inhibitory neurons: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 7.7 6.4 6.6 4.0 8.3 0.5 4.5 7.6 7.3 5.1 10.1 5.8 3.4 6.6 3.6 3.5 7.8 5.6 7.7 6.5 8.7 5.3 5.9 5.7 6.3 9.0 7.9 9.5 2.3 10.7 4.7 2.4 8.2 9.9 3.9 5.8 3.4 8.7 3.6 2.7 4.7 10.2 8.1 7.6 3.2 3.0 8.0 84.9 3.6 7.2 4.7 4.7 3.8 9.5 4.0 1.9 5.2 9.5 28.6 13.4 0.8 16.8 25.3 10.2 15.7 0.1 2.5 10.8 1.1 10.1 7.8 0.2 8.1 6.4 15.4 3.0 2.5 2.3 3.5 0.5 11.3 3.2 0.0 15.3 5.3 4.7 3.2 20.8 4.0 12.0 0.1 5.0 8.4 2.9 11.8 0.0 5.4 0.4 4.7 6.5 6.3 0.1 3.3 6.7 10.0 7.6 4.2 7.3 18.6 4.3 3.6 1.5 10.6 6.5 0.8 9.3 6.9 21.1 21.2 3.4 5.5 0.0 7.4 0.0 0.1 0.3 0.4 0.5 0.3 0.8 0.3 0.4 0.9 1.1 0.7 0.5 0.0 0.7 2.8 1.1 0.0 0.2 6.6 8.3 7.6 7.3 6.5 8.7 9.0 7.9 8.2 8.1 8.0 9.5 5.5 3.2 3.9 18.6 12.9 1.1 4.6 2.2 15.4 4.1 2.8 5.8 6.2 1.5 2.4 9.2 4.2 0.4 10.1 1.4 0.0 0.9 13.2 6.9 6.3 5.8 3.0 1.7 30.2 2.0 0.3 12.6 3.1 6.2 4.5 2.5 8.6 7.3 2.3 1.7 34.3 1.2 0.0 6.2 3.3 9.5 17.7 4.7 19.6 5.6 3.7 9.5 1.0 20.1 12.1 0.4 0.1 17.7 4.2 1.5 9.9 3.0 8.6 3.1 0.0 20.0 8.1 1.0 4.2 2.0 1.4 0.3 3.6 5.1 3.1 0.8 CYP4F8 ENSG00000186526 "Cytochrome P450 family 4 subfamily F member 8" P98187 19 15615218-15630639 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "seminal vesicle: 215.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Breast glandular cells: 1.7;granulocytes: 1.3;NK-cells: 1.0;Prostatic glandular cells: 1.3;Skeletal myocytes: 1.7;Urothelial cells: 2.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 10.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-BR-3: 1.1" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA058960: AB_2683862" "unprognostic (1.70e-2)" "unprognostic (5.46e-3)" "unprognostic (3.21e-2)" "unprognostic (3.97e-6)" "unprognostic (3.51e-3)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (8.25e-2)" "unprognostic (1.15e-2)" "unprognostic (1.02e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.2 215.6 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.4 1.7 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.7 0.0 1.7 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.3 2.5 CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056780-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 124.6;pancreas: 33.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 32.9;Collecting duct cells: 51.5;Distal tubular cells: 70.5;Muller glia cells: 48.0;Proximal tubular cells: 54.1" "Cancer enhanced" "Detected in many" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "RPTEC TERT1: 111.5" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.48e-2)" "unprognostic (8.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-2)" "unprognostic (7.03e-2)" "prognostic favorable (1.27e-5)" "unprognostic (2.19e-3)" "unprognostic (1.47e-1)" "unprognostic (8.93e-2)" "unprognostic (1.20e-2)" 3.1 1.6 6.0 1.2 5.7 0.0 1.9 5.3 7.8 8.4 15.5 11.7 2.5 7.8 3.6 3.9 6.3 9.1 6.1 5.5 5.5 124.6 1.0 6.1 1.1 6.9 6.0 12.4 33.6 1.7 7.2 0.1 5.6 4.9 1.8 2.2 2.9 7.2 1.0 1.5 3.4 5.9 6.4 2.9 3.9 1.0 5.2 0.5 5.6 2.1 2.1 3.5 6.6 5.9 0.0 0.3 0.0 0.0 0.5 2.6 0.1 0.4 1.6 0.2 0.1 0.2 0.0 0.0 0.4 4.4 0.9 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 111.5 0.0 0.0 0.5 0.4 0.3 0.0 1.3 2.0 0.2 0.0 6.0 3.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.7 5.3 7.8 5.5 5.5 6.9 6.0 5.6 6.4 5.2 5.9 0.9 6.4 1.1 1.0 1.0 0.5 0.1 0.6 0.0 10.3 0.5 5.5 7.3 32.9 0.0 51.5 0.0 0.0 0.2 0.0 70.5 7.0 0.1 0.3 0.9 0.6 0.0 0.0 2.9 1.1 0.6 8.8 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 3.4 1.0 0.0 2.8 0.0 48.0 0.0 3.0 0.6 0.4 0.0 4.5 0.1 0.3 0.0 54.1 0.0 1.9 0.0 0.5 3.9 0.0 1.4 0.0 0.1 0.0 0.3 0.1 0.0 0.1 CYTH3 "ARNO3, cytohesin-3, GRP1, PSCD3" ENSG00000008256 "Cytohesin 3" O43739 7 6161776-6272644 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 66.5;Inhibitory neurons: 96.5;Microglial cells: 57.1" "Cancer enriched" "Detected in all" 5 "melanoma: 47.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013979 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA013979: AB_1855799" "unprognostic (6.58e-2)" "unprognostic (1.37e-2)" "unprognostic (1.65e-2)" "unprognostic (5.75e-3)" "unprognostic (1.27e-3)" "unprognostic (1.27e-2)" "unprognostic (2.32e-2)" "unprognostic (2.63e-1)" "unprognostic (8.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (1.73e-2)" "unprognostic (2.20e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (2.63e-5)" 28.8 9.5 16.9 5.4 17.7 7.7 26.5 16.3 20.9 16.4 11.8 18.3 16.5 17.5 6.6 14.0 15.6 11.8 28.5 18.5 15.3 14.2 4.1 19.7 5.4 14.4 15.5 13.9 7.5 11.5 9.8 31.7 15.4 10.2 6.9 5.7 11.9 8.6 15.2 21.6 16.7 12.1 14.2 10.9 13.9 18.6 16.6 5.8 27.7 19.7 4.7 13.8 15.9 17.5 64.7 16.1 15.0 10.4 68.4 80.0 21.2 37.4 32.3 36.1 34.2 25.0 31.3 8.7 22.1 75.5 46.4 59.5 10.4 27.1 23.8 0.6 14.8 2.4 19.8 3.2 32.4 2.7 4.0 57.0 12.1 19.3 27.6 16.2 6.4 12.6 10.3 1.4 26.7 10.6 2.2 11.5 10.4 8.6 21.5 11.5 40.0 5.0 28.0 7.7 9.6 18.4 23.2 79.7 67.0 12.7 4.8 18.1 23.3 24.6 64.4 26.9 23.2 2.9 1.1 9.1 7.9 6.9 102.8 0.3 0.2 0.0 0.9 0.0 2.5 0.1 0.4 1.0 0.1 0.2 0.0 0.6 0.1 1.5 0.2 0.8 0.3 0.2 16.9 17.7 16.3 20.9 18.5 15.3 14.4 15.5 15.4 14.2 16.6 17.5 40.1 16.0 5.8 14.7 3.1 15.2 2.1 1.8 4.0 6.5 9.2 7.5 17.4 2.8 3.2 3.7 8.4 15.4 8.7 9.7 5.9 4.1 14.1 9.4 10.2 14.6 3.0 2.1 66.5 2.8 9.1 24.0 8.2 15.9 12.7 15.8 18.5 1.4 11.9 15.2 96.5 5.5 4.1 4.1 10.9 16.7 16.4 5.9 32.0 57.1 1.9 10.8 3.1 23.1 10.8 10.0 5.4 13.2 4.4 3.9 14.6 1.4 3.7 2.0 39.5 6.1 39.2 24.3 11.2 7.0 11.4 15.2 10.2 10.9 7.1 2.1 DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 87.1;Pancreatic endocrine cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" 59.4 9.3 44.8 17.6 52.5 6.4 36.5 19.3 71.7 59.7 18.6 67.6 9.5 84.4 10.2 30.9 44.7 24.4 39.7 70.1 45.4 52.0 4.0 24.7 9.0 33.8 25.4 34.8 16.9 17.1 45.8 7.1 32.3 29.7 5.9 5.5 33.1 23.9 27.6 36.6 25.0 28.6 24.0 14.2 47.4 27.0 39.7 14.6 33.4 9.0 4.4 61.0 33.1 35.5 17.4 56.1 182.0 319.1 42.4 66.2 56.5 198.6 50.3 113.4 94.5 193.9 59.0 0.3 139.5 155.1 39.0 27.0 80.9 144.0 53.6 5.2 70.4 111.6 72.9 82.0 149.3 43.0 20.5 87.1 37.1 127.3 38.0 113.3 189.4 131.4 54.0 26.0 84.2 25.1 115.1 63.8 264.1 5.7 123.4 338.1 197.2 34.5 85.3 23.7 213.7 289.8 67.0 28.8 111.5 58.4 78.7 42.6 298.6 126.7 169.3 28.2 94.9 6.3 3.1 177.5 53.2 40.5 80.5 9.4 1.4 1.1 10.3 0.8 14.0 0.3 0.3 7.2 1.8 0.4 0.4 5.2 3.2 0.3 0.8 5.8 0.2 2.2 44.8 52.5 19.3 71.7 70.1 45.4 33.8 25.4 32.3 24.0 39.7 35.5 44.2 3.2 1.5 8.1 1.2 10.3 13.7 24.6 9.1 7.0 7.6 9.1 5.1 2.8 11.1 9.2 4.2 1.0 4.5 1.4 1.9 87.1 16.9 8.4 44.0 43.2 40.7 4.8 15.7 43.4 2.8 56.1 11.7 18.4 10.8 49.4 20.7 0.0 1.7 42.1 13.0 2.4 40.7 1.8 8.9 41.6 50.1 6.1 8.8 2.8 2.4 13.4 1.0 5.0 1.0 64.5 0.6 41.0 4.0 16.9 0.6 6.3 5.2 4.5 19.7 10.8 43.4 6.5 26.7 20.1 7.2 0.8 10.4 8.1 3.9 7.5 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DENND2B "HTS1, p126, ST5" ENSG00000166444 "DENN domain containing 2B" P78524 11 8693351-8910951 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 3.2;Cardiomyocytes: 6.2;Cytotrophoblasts: 3.7;Extravillous trophoblasts: 1.8;Fibroblasts: 7.1;Hofbauer cells: 5.8;Smooth muscle cells: 5.7;Syncytiotrophoblasts: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.9" "Lineage enriched" "Detected in single" 4 "monocytes: 2.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046796 Approved Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA046796: AB_2679812" "unprognostic (1.88e-3)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (1.88e-2)" "unprognostic (4.17e-2)" "unprognostic (2.46e-1)" "unprognostic (6.42e-2)" "unprognostic (1.17e-1)" "unprognostic (1.72e-1)" "unprognostic (5.56e-2)" "unprognostic (3.67e-2)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (1.60e-1)" "unprognostic (1.54e-1)" 26.3 60.0 22.0 19.2 20.4 3.4 26.6 26.6 23.2 72.7 38.2 85.4 28.8 130.3 33.2 62.7 104.6 34.6 35.0 19.1 22.3 29.4 27.4 28.8 12.1 29.7 32.6 69.2 27.5 15.4 21.5 26.4 18.3 45.4 26.7 36.5 37.5 62.9 21.9 22.2 30.3 117.2 21.3 59.7 56.9 41.0 28.0 17.5 36.6 11.1 15.1 65.0 50.4 17.1 32.6 4.9 51.8 9.0 16.8 17.6 2.5 28.9 95.8 27.5 25.4 6.8 34.0 1.0 17.2 52.7 12.1 32.2 10.0 41.7 10.8 4.4 12.7 0.0 16.7 22.8 26.9 0.2 0.2 60.8 11.6 15.6 20.1 56.0 5.5 5.0 6.7 2.8 45.4 3.5 1.8 1.5 7.9 32.2 7.7 1.1 31.5 2.0 37.5 23.4 9.8 31.7 25.7 32.1 19.8 17.7 5.4 1.1 14.9 15.8 24.7 50.6 22.8 8.0 15.5 0.2 24.1 0.2 30.4 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.6 0.4 0.0 0.0 0.4 0.0 2.9 0.0 0.1 0.4 22.0 20.4 26.6 23.2 19.1 22.3 29.7 32.6 18.3 21.3 28.0 17.1 3.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 3.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.8 7.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 DEPP1 "C10orf10, DEPP, FIG, Fseg" ENSG00000165507 "DEPP1 autophagy regulator" Q9NTK1 10 44970981-44978809 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 889.5;breast: 697.2" "Cell type enhanced" "Detected in many" "Adipocytes: 192.0;Ductal cells: 146.3;Exocrine glandular cells: 113.0;Glandular and luminal cells: 87.1;Syncytiotrophoblasts: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 143.2;HDLM-2: 106.7;HHSteC: 258.2;HSkMC: 201.6;HUVEC TERT2: 165.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013687, HPA037818, HPA037819" Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria Vesicles "CAB013687: , HPA037818: , HPA037819: AB_2675685" "unprognostic (3.99e-2)" "unprognostic (4.69e-2)" "unprognostic (5.57e-2)" "unprognostic (3.55e-1)" "unprognostic (1.88e-2)" "unprognostic (5.66e-3)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (4.25e-1)" "unprognostic (5.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.89e-2)" "prognostic unfavorable (2.29e-6)" "unprognostic (2.30e-3)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.74e-1)" 889.5 48.4 62.3 19.4 71.4 4.5 697.2 59.5 71.8 153.0 50.3 145.7 16.7 168.5 16.5 65.7 334.2 68.5 260.6 55.5 71.9 95.4 131.6 508.6 63.0 175.9 72.3 297.8 349.7 23.0 85.2 76.5 93.4 82.6 12.0 28.2 119.7 22.8 165.8 165.0 94.8 68.8 101.6 32.8 104.6 19.3 87.4 25.2 200.5 52.2 47.6 177.6 139.1 90.6 30.2 0.2 0.5 0.4 143.2 69.5 7.4 0.2 10.2 0.4 1.8 1.1 11.2 0.0 1.6 13.5 7.1 1.2 1.2 9.1 0.7 106.7 4.0 0.1 0.1 11.0 258.2 0.1 0.1 201.6 0.4 0.1 1.4 24.9 165.0 0.0 0.2 63.2 0.6 0.0 0.1 1.7 0.2 0.6 0.9 5.1 1.7 25.7 0.5 10.9 5.6 0.3 0.0 1.3 5.8 17.0 0.2 7.0 1.6 7.8 5.6 0.5 7.3 1.7 2.8 0.4 44.2 2.6 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.4 62.3 71.4 59.5 71.8 55.5 71.9 175.9 72.3 93.4 101.6 87.4 90.6 192.0 0.0 24.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 47.0 27.8 0.0 0.0 6.2 31.3 0.0 53.8 1.4 0.0 37.2 146.3 0.0 61.3 33.2 60.0 0.0 0.0 0.0 113.0 14.7 79.3 0.0 87.1 0.0 8.4 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 65.0 0.0 0.0 0.5 0.0 0.0 25.5 5.8 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 300.2 1.8 0.8 0.0 0.0 DKK2 ENSG00000155011 "Dickkopf WNT signaling pathway inhibitor 2" Q9UBU2 4 106921802-107283806 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 15.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.6;Fibroblasts: 18.7;Hofbauer cells: 16.8;Inhibitory neurons: 32.5;Langerhans cells: 11.8;Suprabasal keratinocytes: 7.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 22.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebral cortex: 1.5;midbrain: 5.0;pons: 6.3;thalamus: 5.7" "CAB009727, HPA052611" Uncertain Supported "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "CAB009727: AB_2091492, HPA052611: AB_2732576" "unprognostic (3.14e-3)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (3.21e-2)" "unprognostic (9.75e-2)" "unprognostic (3.68e-1)" "unprognostic (1.04e-3)" "unprognostic (2.47e-2)" "unprognostic (5.11e-1)" "unprognostic (5.21e-2)" "unprognostic (3.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (6.86e-2)" "unprognostic (3.22e-1)" "unprognostic (4.58e-2)" 1.4 0.8 0.4 0.4 1.4 0.0 3.0 0.0 1.5 15.2 1.2 1.7 0.0 1.0 0.4 1.2 0.5 0.7 2.2 0.7 0.6 0.2 0.2 5.3 0.7 0.9 4.5 4.4 0.2 0.6 1.5 2.8 0.3 2.3 0.5 0.4 1.3 1.7 1.9 4.7 0.3 0.6 0.2 1.3 0.1 0.1 2.3 1.0 0.9 1.2 3.0 0.2 0.8 0.8 0.0 0.0 3.6 0.0 0.6 0.3 0.0 0.1 0.3 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 1.5 0.7 0.6 0.9 4.5 0.3 0.2 2.3 0.8 2.6 0.0 0.0 0.3 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.1 5.4 0.0 0.0 5.2 0.0 0.2 18.7 0.0 0.1 0.0 0.0 3.3 0.0 16.8 0.0 32.5 0.0 0.0 0.3 11.8 0.0 4.1 0.3 7.2 2.8 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 7.4 0.0 0.8 2.0 0.0 0.0 DMRT3 DMRTA3 ENSG00000064218 "Doublesex and mab-3 related transcription factor 3" Q9NQL9 9 976655-991732 "Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 10.2;parathyroid gland: 26.9;testis: 10.1" "Cell type enhanced" "Detected in some" "Early spermatids: 4.8;Smooth muscle cells: 2.3;Spermatocytes: 13.9;Spermatogonia: 5.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.0;HEK 293: 1.4;hTERT-RPE1: 2.1;THP-1: 2.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" HPA077685 Approved NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA077685: AB_2732357" "unprognostic (2.42e-1)" "unprognostic (2.26e-1)" "unprognostic (1.51e-2)" "unprognostic (2.13e-4)" "unprognostic (1.73e-2)" "unprognostic (3.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (3.84e-1)" "unprognostic (2.12e-3)" "unprognostic (2.91e-2)" "unprognostic (5.84e-1)" "unprognostic (1.05e-2)" "unprognostic (1.11e-1)" 3.3 0.0 0.7 0.0 0.2 0.0 1.7 0.0 1.0 0.0 10.2 0.1 0.0 0.1 0.0 0.3 0.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 2.0 0.2 0.2 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.6 0.0 0.2 0.1 0.0 0.0 10.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 1.0 1.4 0.0 0.2 0.2 0.0 0.1 0.0 1.4 1.5 0.0 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.3 0.5 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.3 13.9 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DNAI3 "DIC3, FLJ30067, NYD-SP29, WDR63" ENSG00000162643 "Dynein axonemal intermediate chain 3" Q8IWG1 1 84999147-85133138 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 21.9;choroid plexus: 23.9;fallopian tube: 14.5;testis: 18.9" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.2" "Group enriched" "Detected in some" 5 "endometrial cancer: 1.3;melanoma: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 8.4;HBEC3-KT: 4.4;HSkMC: 5.6;hTCEpi: 6.9;LHCN-M2: 6.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038526 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "HPA038526: AB_2676063" "unprognostic (3.12e-2)" "unprognostic (1.33e-1)" "unprognostic (1.34e-1)" "unprognostic (1.61e-2)" "unprognostic (1.09e-4)" "unprognostic (1.10e-3)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.56e-1)" "unprognostic (2.53e-1)" "unprognostic (1.82e-3)" "unprognostic (2.31e-1)" "unprognostic (1.14e-5)" "unprognostic (8.57e-3)" "unprognostic (2.60e-1)" "unprognostic (2.35e-2)" "unprognostic (1.82e-1)" 0.2 21.9 1.8 0.4 1.8 0.0 0.2 1.6 0.9 0.9 23.9 0.7 0.2 0.6 4.1 0.3 14.5 0.4 0.8 2.4 2.6 0.7 0.1 1.8 0.4 7.7 10.0 0.1 0.5 5.7 3.0 0.5 5.7 0.3 0.5 0.7 0.8 0.2 0.1 2.1 0.1 0.4 6.6 0.2 0.1 18.9 2.5 0.8 1.1 2.2 0.2 0.5 0.1 4.0 0.1 0.4 0.1 0.3 3.0 8.4 1.6 1.7 3.4 0.5 0.9 0.0 0.5 0.4 0.0 0.3 2.0 0.0 0.3 4.4 0.7 0.0 0.3 0.2 0.0 0.0 0.5 0.0 0.0 5.6 6.9 2.9 0.2 0.3 0.1 0.5 0.0 0.0 6.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.2 0.1 0.0 0.0 0.2 1.1 1.6 0.0 2.9 0.0 0.5 0.2 0.0 0.4 0.0 0.0 0.3 3.3 0.1 1.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.1 1.8 1.8 1.6 0.9 2.4 2.6 7.7 10.0 5.7 6.6 2.5 4.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in all" "Adipocytes: 362.9;Oligodendrocytes: 367.2" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Cell line enhanced" "Detected in many" "ASC diff: 263.7;Karpas-707: 279.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" 60.0 34.8 252.6 22.5 348.0 3.5 48.0 332.4 266.7 25.3 0.0 44.8 10.4 24.9 11.4 18.3 29.6 29.4 58.6 276.1 263.2 21.3 17.6 78.2 17.4 362.4 296.0 40.8 11.0 7.1 22.1 43.7 389.9 19.7 19.0 64.0 18.5 14.9 19.2 25.8 27.6 32.9 257.9 33.6 21.5 11.2 305.0 19.3 22.5 25.8 20.1 35.6 26.9 549.9 22.0 104.1 100.2 53.9 263.7 120.6 9.8 41.9 97.0 39.2 50.6 41.0 31.0 32.7 29.7 131.7 78.8 20.9 106.6 42.0 37.1 74.2 9.2 37.0 36.9 57.9 168.5 8.0 14.5 150.8 59.5 107.1 61.9 125.5 80.0 24.9 1.1 279.1 39.9 13.9 64.3 8.1 78.8 69.9 20.0 84.3 40.3 21.8 66.2 25.0 45.6 95.8 51.0 0.5 28.6 65.7 7.8 14.8 145.0 88.2 34.8 74.3 18.5 39.1 43.3 24.8 127.7 48.1 46.0 1.3 65.8 0.6 9.1 74.5 3.3 8.5 8.1 6.2 71.2 4.4 4.0 5.2 1.7 11.3 48.8 42.2 13.3 30.3 252.6 348.0 332.4 266.7 276.1 263.2 362.4 296.0 389.9 257.9 305.0 549.9 362.9 131.4 71.7 193.9 11.5 40.4 1.0 13.2 2.2 111.4 44.4 58.4 105.0 84.4 19.4 22.0 31.3 15.1 64.8 4.5 3.9 21.4 3.1 41.6 154.3 154.6 60.7 22.3 191.9 2.0 9.1 144.9 6.1 33.6 20.8 33.0 211.3 22.8 51.1 141.3 157.0 87.0 4.1 223.5 192.3 10.6 109.0 111.1 120.9 81.5 163.5 165.2 22.6 102.1 367.2 12.6 6.2 89.5 6.5 1.1 4.7 24.4 10.5 38.6 138.1 51.8 110.6 3.8 17.0 1.6 33.8 4.5 14.8 16.8 12.1 1.2 EBF1 "COE1, EBF, OLF1" ENSG00000164330 "EBF transcription factor 1" Q9UH73 5 158695916-159099916 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.7" "Cell type enhanced" "Detected in many" "Adipocytes: 79.8;Fibroblasts: 108.4;Leydig cells: 285.5;Microglial cells: 255.8;Peritubular cells: 121.5;Sertoli cells: 98.6;Smooth muscle cells: 138.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 12.1;naive B-cell: 10.2" "Lineage enriched" "Detected in single" 24 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "ASC diff: 30.0;HSkMC: 26.7;REH: 82.6;U-2197: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (7.86e-2)" "unprognostic (3.08e-2)" "unprognostic (7.29e-2)" "unprognostic (4.70e-2)" "unprognostic (2.63e-1)" "unprognostic (1.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" "unprognostic (5.75e-2)" "unprognostic (1.60e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (9.62e-7)" "prognostic unfavorable (7.80e-4)" "unprognostic (5.75e-2)" "unprognostic (5.81e-2)" "unprognostic (4.37e-3)" 37.7 2.8 4.6 3.8 5.0 3.3 20.5 16.4 5.0 14.6 3.9 5.1 1.1 10.5 4.1 3.5 12.5 8.1 7.9 3.8 5.0 3.3 0.4 4.3 9.4 9.8 7.5 8.5 1.7 1.6 2.4 10.8 7.1 4.8 3.2 2.0 4.7 4.4 4.7 7.6 5.5 7.7 11.6 4.7 3.5 4.0 5.3 2.5 7.5 7.4 9.2 10.4 10.3 4.9 0.0 0.5 12.8 0.0 30.0 11.9 0.2 0.3 0.0 0.7 1.7 0.0 0.0 11.9 0.0 4.0 2.4 0.1 0.5 0.1 0.2 2.8 0.2 0.0 3.5 0.0 1.0 0.1 0.3 26.7 0.0 11.4 0.4 0.0 0.0 0.3 0.0 0.2 0.9 0.0 0.1 0.2 1.2 0.0 0.0 82.6 0.6 0.2 0.0 0.0 6.8 1.7 0.7 0.3 0.0 0.2 0.0 0.1 0.0 15.3 1.8 17.5 0.3 0.0 0.1 11.1 10.2 1.2 13.0 0.5 0.0 0.1 0.0 0.0 0.0 12.1 0.0 0.0 0.0 10.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 4.6 5.0 16.4 5.0 3.8 5.0 9.8 7.5 7.1 11.6 5.3 4.9 79.8 0.0 0.5 5.2 76.3 12.2 0.3 0.0 1.8 5.9 0.8 1.9 5.0 0.0 0.7 1.8 0.0 0.2 0.2 0.1 0.0 3.9 28.2 1.5 54.2 56.3 0.0 0.4 0.4 0.0 0.3 108.4 1.5 1.4 0.0 0.0 4.6 2.2 0.8 0.0 1.6 0.1 0.0 0.3 16.6 21.7 285.5 1.9 14.2 255.8 9.3 1.9 0.0 3.0 0.9 0.1 0.0 121.5 7.7 0.7 0.0 0.1 0.9 2.3 98.6 4.6 138.8 2.7 1.3 1.6 7.0 0.4 5.0 10.7 0.0 1.7 EBF2 "COE2, FLJ11500" ENSG00000221818 "EBF transcription factor 2" Q9HAK2 8 25841725-26045413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.8" "Cell type enhanced" "Detected in some" "Adipocytes: 11.9;Fibroblasts: 23.2;Microglial cells: 13.1;Sertoli cells: 39.5;Smooth muscle cells: 53.4" "Cancer enhanced" "Detected in many" "renal cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 22.7;ASC TERT1: 45.7;HSkMC: 46.9;hTEC/SVTERT24-B: 26.7;U-138 MG: 17.1;U-2197: 22.7;U-87 MG: 19.1" "Group enriched" "Detected in many" 4 "basal ganglia: 5.7;cerebellum: 3.1;hypothalamus: 2.0;midbrain: 4.4;pons and medulla: 2.8" "Region enriched" "Detected in many" 5 "spinal cord: 8.7" "HPA003954, HPA055101" Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA003954: , HPA055101: " "unprognostic (3.70e-1)" "unprognostic (3.88e-3)" "unprognostic (2.69e-2)" "unprognostic (2.47e-3)" "unprognostic (1.03e-1)" "unprognostic (6.10e-2)" "unprognostic (5.92e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-2)" "unprognostic (6.13e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (7.41e-4)" "unprognostic (2.28e-1)" "unprognostic (3.80e-2)" "unprognostic (1.82e-2)" 17.8 0.7 0.2 0.9 0.5 0.0 8.0 0.2 0.1 0.7 0.1 1.4 0.0 0.8 1.9 0.8 4.0 2.6 9.8 0.0 0.7 0.5 0.0 0.6 0.6 1.3 3.1 1.0 0.8 2.2 0.4 0.5 2.7 0.5 0.4 0.2 1.4 0.4 4.7 1.5 0.7 1.7 3.8 0.0 0.8 1.1 0.9 1.4 6.2 9.6 0.2 1.9 1.2 0.3 0.0 0.0 0.8 0.0 22.7 45.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 26.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 17.1 0.2 22.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.7 1.3 3.1 2.7 3.8 0.9 0.3 11.9 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.6 0.1 0.2 0.3 5.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 5.6 0.0 0.0 0.5 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 3.2 5.9 0.6 0.0 13.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 39.5 2.6 53.4 1.0 0.2 0.4 0.3 0.0 0.2 0.1 0.0 0.1 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 84.3;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cell line enhanced" "Detected in many" "EFO-21: 5.2;Hep G2: 17.9;OE19: 5.1;RPMI-8226: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Lipid droplets" "HPA037972: AB_2675761, HPA037973: AB_2675762" "unprognostic (3.76e-2)" "unprognostic (8.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.59e-3)" "unprognostic (7.85e-2)" "unprognostic (1.25e-4)" "unprognostic (4.33e-4)" "unprognostic (5.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "prognostic favorable (1.04e-9)" "unprognostic (8.63e-4)" "unprognostic (7.64e-2)" "unprognostic (9.85e-2)" "unprognostic (2.79e-1)" 4.2 8.5 2.4 0.7 3.0 0.1 2.8 2.2 2.6 4.9 5.2 2.6 0.5 3.0 3.2 1.5 3.8 2.0 10.4 2.1 2.4 3.7 2.1 3.2 0.8 3.2 2.8 4.9 4.2 9.7 1.3 1.8 3.0 3.4 1.1 0.3 2.2 2.2 1.7 4.2 1.1 2.1 2.3 1.4 3.8 1.2 3.1 1.2 6.0 2.0 0.6 2.3 3.9 4.6 0.0 0.6 0.3 2.8 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 5.2 0.2 0.2 0.5 3.8 1.4 0.0 0.0 4.5 0.0 0.0 17.9 1.0 0.0 1.1 1.8 1.3 0.0 0.9 0.0 0.5 3.5 0.0 4.9 0.0 1.2 0.0 0.0 2.8 5.1 0.3 0.0 1.2 6.0 0.1 0.0 1.5 0.0 0.1 0.3 0.1 2.0 0.3 0.1 0.5 1.7 2.2 2.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.8 0.0 0.0 0.1 2.4 3.0 2.2 2.6 2.1 2.4 3.2 2.8 3.0 2.3 3.1 4.6 3.3 3.2 0.5 21.2 0.3 3.8 2.6 2.0 6.8 0.2 0.9 1.5 12.1 0.0 1.1 5.5 0.0 0.2 0.1 1.0 0.0 1.3 21.3 4.6 1.2 2.2 1.8 0.0 17.9 1.3 0.2 6.0 5.6 12.2 0.0 0.5 11.0 1.2 4.1 0.0 9.6 0.6 0.0 4.8 1.2 9.2 4.7 2.8 1.8 84.3 0.1 1.3 0.0 30.2 45.9 1.1 0.1 2.2 0.2 2.3 0.4 3.1 1.3 0.1 6.6 10.7 5.4 1.7 3.5 3.2 4.1 0.0 2.1 0.4 0.9 1.5 EEA1 ZFYVE2 ENSG00000102189 "Early endosome antigen 1" Q15075 12 92770637-92929331 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005861, CAB018782, HPA038158, HPA038159" Supported Supported Vesicles NA NA 20000 "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB005861: AB_2262056, CAB018782: AB_2277714, HPA038158: AB_10966710, HPA038159: AB_10962356" "unprognostic (5.38e-2)" "unprognostic (4.60e-1)" "unprognostic (2.00e-2)" "unprognostic (5.62e-2)" "unprognostic (1.62e-1)" "unprognostic (1.81e-2)" "unprognostic (6.75e-2)" "unprognostic (6.87e-2)" "unprognostic (1.31e-1)" "unprognostic (5.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-3)" "unprognostic (5.86e-2)" "unprognostic (2.85e-1)" "unprognostic (3.89e-2)" "unprognostic (1.65e-1)" 11.4 6.6 2.8 6.7 3.0 3.7 7.2 6.6 4.3 9.3 0.0 8.2 6.7 8.7 4.1 13.1 4.8 7.3 7.8 2.7 3.8 6.6 9.5 7.1 5.6 5.3 4.3 8.9 6.0 8.1 2.8 9.4 5.5 7.3 7.0 13.7 7.0 5.7 9.6 10.2 6.6 8.4 3.2 7.3 7.0 5.3 3.5 4.1 8.1 10.4 5.5 8.5 6.8 4.4 14.9 4.9 7.2 5.1 30.1 30.1 16.4 28.8 16.6 15.0 10.6 17.1 4.0 15.2 5.1 20.3 21.3 17.5 16.0 8.1 23.0 10.2 7.8 16.2 5.9 15.7 16.7 11.6 7.3 19.7 11.7 16.1 24.0 16.7 25.3 4.2 12.2 5.0 15.7 6.9 8.4 7.9 7.2 6.0 10.5 9.2 18.2 10.1 7.7 20.4 6.0 4.4 21.2 13.7 12.9 9.9 18.2 10.1 34.4 21.0 8.0 16.8 11.2 5.4 10.1 10.2 7.8 10.1 11.6 0.0 0.6 0.2 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.4 0.8 0.5 0.5 0.2 0.9 0.5 0.1 0.2 2.8 3.0 6.6 4.3 2.7 3.8 5.3 4.3 5.5 3.2 3.5 4.4 58.3 99.3 59.8 60.7 36.4 37.9 57.6 25.2 35.9 53.1 26.5 24.9 93.0 17.2 32.8 25.8 37.5 65.5 39.4 35.7 43.0 59.0 15.1 37.1 85.7 58.9 16.8 14.9 58.5 34.7 45.8 81.1 29.0 53.6 32.9 29.8 31.4 37.4 36.4 183.4 76.2 26.6 14.2 38.6 36.8 9.5 61.8 44.5 48.0 68.4 44.0 60.0 28.8 94.5 102.5 40.4 35.9 68.1 19.8 50.0 26.3 35.3 26.4 68.4 46.0 104.4 71.0 131.1 30.0 91.3 50.3 113.6 29.8 35.5 30.7 78.1 EEF2K "CaMKIII, eEF-2K" ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206278-22288738 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 49.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 69.1;Late spermatids: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.5;HL-60: 1.6;HMC-1: 1.8;NB-4: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB007818: AB_598150, HPA056061: AB_2683021" "unprognostic (4.79e-2)" "unprognostic (6.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.94e-2)" "unprognostic (5.09e-3)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.74e-1)" "unprognostic (8.50e-2)" "unprognostic (2.01e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 19.8 7.1 1.0 0.4 0.9 0.7 15.9 1.5 2.2 17.2 0.7 20.1 0.3 14.3 0.7 9.1 13.1 0.3 9.2 0.9 1.2 3.6 7.8 9.0 0.5 1.1 0.9 8.2 12.9 0.0 5.2 0.4 1.2 19.6 0.2 0.3 15.0 0.2 24.9 49.0 8.1 0.3 0.9 8.0 9.8 2.3 1.4 0.0 6.3 0.0 0.2 18.8 15.4 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 1.5 0.2 0.0 0.0 0.1 0.0 0.6 0.2 1.0 0.0 1.6 1.8 0.0 0.4 0.1 0.1 0.3 0.1 0.1 0.2 1.3 0.0 0.0 0.1 1.6 0.1 0.4 0.0 0.4 1.0 0.2 0.4 0.0 0.3 0.6 0.0 0.0 0.2 0.1 0.2 0.5 0.5 0.7 0.3 1.4 0.0 0.3 0.1 0.3 1.0 1.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.4 0.1 0.0 1.0 0.9 1.5 2.2 0.9 1.2 1.1 0.9 1.2 0.9 1.4 1.1 43.7 22.4 13.3 22.5 7.3 12.6 9.6 3.9 31.3 69.1 15.4 9.3 17.3 12.8 9.8 9.2 14.6 16.3 12.7 24.2 0.0 4.9 42.9 42.4 12.6 18.4 3.0 7.6 21.2 13.4 11.7 19.2 26.0 34.9 29.2 12.0 22.5 17.7 18.7 1.7 37.4 12.3 4.1 15.3 16.2 76.6 14.3 8.7 8.8 15.9 7.9 6.1 6.2 31.7 8.6 10.2 26.3 15.8 19.6 6.6 12.5 4.0 14.9 21.6 6.6 43.5 10.0 1.3 4.2 16.9 23.0 7.8 7.8 5.7 8.1 6.7 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EGR1 "AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225" ENSG00000120738 "Early growth response 1" P18146 5 138465479-138469303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 1113.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 133.1" "Immune cell enhanced" "Detected in some" "neutrophil: 7.1" "Group enriched" "Detected in many" 7 "granulocytes: 7.1;monocytes: 3.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 192.0;hTCEpi: 286.6;U-266/84: 478.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019427, HPA029937, HPA029938" Supported Enhanced Nucleoplasm No No "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB019427: AB_2097038, HPA029937: AB_2673258, HPA029938: AB_2673259" "unprognostic (5.47e-2)" "unprognostic (4.09e-1)" "unprognostic (1.57e-1)" "unprognostic (7.74e-2)" "unprognostic (6.32e-2)" "unprognostic (2.66e-1)" "unprognostic (1.80e-1)" "unprognostic (2.96e-1)" "unprognostic (7.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.75e-1)" "unprognostic (2.94e-2)" "unprognostic (3.51e-3)" "unprognostic (3.57e-2)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (1.98e-3)" 565.5 354.0 7.5 135.4 15.9 176.7 173.9 133.1 70.1 302.5 10.0 246.5 54.8 197.6 13.5 370.9 911.7 345.2 258.8 20.7 30.4 173.2 149.5 173.4 145.2 9.9 13.2 974.6 137.0 93.5 243.3 54.2 12.9 309.7 161.1 56.0 140.9 84.4 66.0 363.1 107.2 474.3 4.4 77.5 254.5 26.9 10.4 301.5 584.4 354.9 19.1 191.4 115.9 19.5 21.8 0.9 45.0 67.6 119.6 192.0 5.1 36.7 22.7 48.4 39.0 26.4 18.9 1.1 5.9 80.2 165.8 10.1 2.6 74.5 22.2 1.1 3.3 3.0 11.5 7.6 15.5 8.0 57.8 15.2 286.6 43.2 9.8 37.6 4.2 53.9 112.5 26.0 14.3 108.2 3.2 34.1 4.1 80.3 0.1 0.8 6.7 4.1 36.8 13.1 56.5 6.4 44.7 120.1 106.6 43.3 1.5 6.6 1.8 17.5 22.6 8.7 14.2 60.1 478.8 8.6 20.3 103.5 5.2 0.0 2.6 0.3 0.1 3.6 0.0 0.7 0.1 0.0 0.7 0.2 0.1 0.1 7.1 0.1 1.2 0.0 0.2 0.5 7.5 15.9 133.1 70.1 20.7 30.4 9.9 13.2 12.9 4.4 10.4 19.5 920.4 275.7 485.6 6.8 116.4 181.8 719.6 207.4 816.1 43.5 550.0 459.0 652.4 420.4 124.0 29.5 64.6 159.5 46.2 645.2 7.9 255.4 1.4 356.0 836.5 383.1 960.5 27.3 20.3 101.7 110.1 989.9 736.0 645.4 354.0 274.8 347.0 183.1 131.4 3.3 2.7 747.6 93.6 218.6 109.7 3.8 164.7 300.7 106.7 20.6 8.6 191.6 0.0 1.5 2.4 135.3 380.8 53.0 67.2 405.1 224.8 5.7 127.4 101.3 223.5 1113.1 613.2 3.2 2.9 644.8 200.3 129.7 83.4 104.9 480.2 145.4 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "bone marrow: 3894.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.7;Fibroblasts: 16.2;Langerhans cells: 11.1;Leydig cells: 6.2;Melanocytes: 7.2;Suprabasal keratinocytes: 7.4" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 4.0;neutrophil: 12.1" "Group enriched" "Detected in many" 9 "granulocytes: 12.1;monocytes: 4.0" "Cell line enriched" "Detected in some" 91 "THP-1: 3105.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015409, HPA066836, HPA073774" Enhanced "Secreted to blood" NA NA 370000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015409: AB_831596, HPA066836: AB_2685733, HPA073774: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 3.4 1.0 0.3 0.0 0.3 3894.9 3.4 0.1 0.7 0.5 0.2 2.0 0.4 1.0 0.0 1.1 1.4 0.1 4.0 0.3 0.2 0.7 3.3 19.4 0.6 0.1 0.2 0.5 0.5 0.0 1.2 0.8 0.1 2.9 0.0 0.0 2.4 0.1 1.5 5.4 1.8 0.1 0.1 42.6 1.4 0.4 0.2 6.3 3.1 0.0 0.0 2.1 1.0 0.2 2.0 0.1 0.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3105.0 0.0 0.0 0.1 0.0 1.3 0.0 0.2 0.8 0.0 34.0 0.0 0.0 4.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 27.2 0.3 0.3 0.1 0.7 0.3 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.9 0.0 0.0 0.0 0.3 8.7 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 0.0 4.2 0.1 0.0 1.3 16.2 0.0 0.1 0.0 0.0 0.7 0.9 0.2 0.0 0.1 0.0 0.0 3.4 11.1 0.0 6.2 1.1 7.2 0.0 0.9 0.0 1.0 0.0 0.1 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.2 0.0 0.0 7.4 0.0 0.7 0.2 0.0 0.0 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 EN1 ENSG00000163064 "Engrailed homeobox 1" Q05925 2 118842171-118847648 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.2;skeletal muscle: 13.9;skin 1: 10.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 5.6;Fibroblasts: 4.8;Melanocytes: 12.4;Skeletal myocytes: 12.0;Smooth muscle cells: 5.4" "Cancer enhanced" "Detected in many" "breast cancer: 5.6" "Region enriched" "Detected in many" 6 "midbrain: 18.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.1;ASC TERT1: 7.2;fHDF/TERT166: 13.3;HSkMC: 13.5;PC-3: 7.8;U-138 MG: 9.9;U-2197: 11.2" "Region enriched" "Detected in single" 5 "midbrain: 4.9" "Region enriched" "Detected in some" 6 "midbrain: 23.6" "CAB014884, HPA073141" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli rim" Nucleoplasm "CAB014884: , HPA073141: AB_2686573" "unprognostic (5.20e-2)" "unprognostic (1.61e-1)" "unprognostic (5.78e-2)" "unprognostic (4.84e-7)" "unprognostic (1.87e-3)" "unprognostic (1.90e-1)" "unprognostic (1.95e-3)" "unprognostic (1.16e-1)" "unprognostic (2.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.46e-1)" "unprognostic (3.38e-9)" "unprognostic (2.15e-2)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (9.30e-3)" 3.5 0.2 0.1 0.0 0.1 0.0 1.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.8 0.7 18.2 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 13.9 10.4 0.0 0.0 0.5 0.0 0.0 0.1 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.5 4.0 0.2 0.6 0.2 16.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 4.7 0.5 0.6 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.1 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.0 9.9 1.0 11.2 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.5 0.7 18.2 3.2 0.5 1.4 0.5 1.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 5.6 2.8 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 5.4 0.1 0.4 0.0 2.6 0.0 0.2 0.0 0.0 0.0 ESYT2 "CHR2SYT, FAM62B, KIAA1228" ENSG00000117868 "Extended synaptotagmin 2" A0FGR8 7 158730995-158830253 "Plasma proteins, Predicted membrane proteins, Transporters" "Endocytosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 185.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002132, HPA070823" Approved Approved "Plasma membrane,Cytosol" NA NA 24000 "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA002132: AB_1078807, HPA070823: " "unprognostic (2.30e-1)" "unprognostic (1.06e-2)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (5.72e-2)" "unprognostic (5.43e-2)" "unprognostic (9.01e-2)" "unprognostic (9.94e-2)" "unprognostic (1.72e-1)" "unprognostic (8.71e-3)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.13e-1)" "unprognostic (7.54e-2)" "unprognostic (6.70e-2)" "unprognostic (4.58e-2)" "unprognostic (3.70e-3)" "prognostic unfavorable (2.81e-5)" 53.9 37.0 24.0 25.6 25.0 34.8 33.9 21.8 28.7 30.8 22.7 38.4 22.3 36.1 30.1 45.0 34.4 32.2 35.1 27.7 25.3 27.2 24.5 33.4 27.5 22.1 24.6 48.1 29.2 30.9 20.6 43.3 24.6 25.3 30.3 14.2 32.1 30.5 44.9 31.0 27.6 38.7 21.7 21.4 25.5 15.8 30.7 37.0 39.3 41.8 25.4 35.8 29.3 19.4 92.9 57.8 19.5 19.8 62.2 72.6 55.3 47.5 48.9 36.7 40.6 29.7 106.1 27.5 52.2 86.2 66.6 46.0 27.8 50.2 35.1 31.5 28.3 26.2 44.0 32.2 64.1 95.0 55.8 53.4 51.8 41.8 55.2 73.1 44.8 81.9 56.4 97.8 61.9 71.7 96.0 66.7 29.2 53.9 56.7 82.4 37.0 38.8 58.6 38.4 46.8 30.2 151.6 109.7 66.7 43.4 37.7 96.3 69.3 40.3 18.8 178.7 60.5 68.6 17.3 27.5 102.4 93.8 121.5 1.7 1.4 1.2 6.1 1.8 3.4 1.1 5.1 4.3 2.8 0.6 4.6 5.5 0.9 5.4 1.2 1.8 4.2 2.3 24.0 25.0 21.8 28.7 27.7 25.3 22.1 24.6 24.6 21.7 30.7 19.4 65.7 38.5 32.4 55.5 18.1 46.1 12.9 22.6 19.4 15.0 32.6 21.6 30.8 21.5 33.7 47.8 16.7 31.6 54.0 41.0 3.9 15.3 18.0 60.6 17.8 48.5 21.1 17.7 137.1 20.0 26.1 44.2 15.8 47.0 12.6 36.8 23.2 20.9 20.2 13.5 119.3 31.2 24.4 20.2 83.6 5.3 35.1 27.7 51.6 185.5 21.9 12.1 43.3 67.3 61.4 29.9 14.1 54.5 36.2 23.2 28.0 8.7 61.8 10.8 32.9 42.6 60.4 10.6 10.2 22.0 51.7 40.8 43.4 19.5 26.0 25.8 EVC DWF-1 ENSG00000072840 "EvC ciliary complex subunit 1" P57679 4 5711201-5814305 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Microglial cells: 10.3;Skeletal myocytes: 10.5" "Cancer enhanced" "Detected in all" "renal cancer: 16.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 62.3;hTERT-HME1: 60.7;hTERT-RPE1: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008703, HPA016046" Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "HPA008703: AB_1078765, HPA016046: AB_1848299" "unprognostic (1.69e-1)" "unprognostic (5.39e-2)" "unprognostic (1.15e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (9.37e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-1)" "unprognostic (2.56e-2)" "unprognostic (9.63e-2)" "unprognostic (2.82e-1)" "prognostic favorable (5.60e-9)" "unprognostic (3.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-2)" "prognostic unfavorable (9.47e-5)" 6.6 3.3 2.2 3.0 2.4 0.1 5.4 1.5 1.4 10.3 4.4 8.4 1.9 13.7 8.3 8.1 13.9 14.1 7.2 1.6 2.1 26.0 2.8 8.3 2.8 3.7 2.4 33.5 9.3 18.8 1.9 3.6 1.7 11.4 3.4 1.7 9.6 9.8 1.4 7.8 3.0 11.7 2.5 3.0 4.6 3.5 2.7 4.2 9.4 3.3 2.8 7.0 6.0 1.3 7.5 9.4 5.1 13.4 32.6 46.7 1.8 16.3 62.3 18.6 23.9 0.0 0.0 0.0 5.1 26.2 31.0 8.7 5.4 13.5 15.2 12.4 3.7 0.0 5.6 2.5 24.1 0.0 1.4 23.2 19.4 24.8 60.7 53.0 13.1 0.0 0.1 0.1 43.6 0.0 0.0 0.0 5.6 0.0 8.6 11.4 14.1 0.2 6.4 1.3 2.9 8.7 0.0 0.0 6.4 4.9 3.4 0.6 22.9 15.8 3.0 11.3 14.5 9.9 8.6 0.8 45.2 0.0 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 1.5 1.4 1.6 2.1 3.7 2.4 1.7 2.5 2.7 1.3 0.5 3.2 2.3 26.4 0.1 3.4 1.9 3.6 2.2 0.5 0.5 1.1 2.0 1.5 2.2 3.7 0.0 0.1 0.0 0.0 1.9 0.6 0.5 0.8 6.6 0.7 0.0 0.4 1.2 0.0 0.0 6.5 1.5 4.5 0.0 1.5 0.7 0.8 0.0 0.0 1.1 0.0 2.0 0.0 1.0 0.2 0.9 0.2 5.4 10.3 0.0 2.0 0.0 2.0 0.1 0.3 0.0 0.7 0.4 0.9 0.0 1.5 1.5 0.1 0.0 10.5 2.6 0.0 0.0 2.0 2.8 0.1 0.9 2.4 0.0 1.2 EVC2 LBN ENSG00000173040 "EvC ciliary complex subunit 2" Q86UK5 4 5542772-5709548 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 17.6;Basal squamous epithelial cells: 12.0;Fibroblasts: 8.9;Leydig cells: 11.5;Skeletal myocytes: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.7;HHSteC: 13.0;hTERT-HME1: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040910, HPA048122" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Microtubules, Cytokinetic bridge" "Nucleoplasm, Cytosol" "HPA040910: AB_2677195, HPA048122: AB_2680272" "unprognostic (6.56e-2)" "unprognostic (6.74e-2)" "unprognostic (5.10e-2)" "unprognostic (2.25e-1)" "unprognostic (8.23e-3)" "unprognostic (2.80e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (8.57e-2)" "unprognostic (9.37e-2)" "prognostic favorable (1.58e-4)" "unprognostic (2.51e-2)" "unprognostic (3.14e-1)" "unprognostic (5.61e-2)" "unprognostic (6.29e-5)" 4.8 0.7 1.3 1.5 1.4 0.1 3.6 1.2 1.1 6.0 2.3 3.7 0.6 4.7 1.7 2.2 4.7 2.7 3.1 1.3 1.4 2.6 0.7 2.1 1.9 1.6 1.5 7.8 1.7 3.1 1.1 1.3 1.2 3.2 0.6 0.3 2.8 2.0 1.1 3.8 2.0 2.3 1.4 1.0 2.1 1.6 1.5 1.0 3.8 1.9 1.7 4.1 4.4 1.3 0.0 2.7 0.0 6.6 8.4 9.3 0.0 4.1 9.7 3.6 6.0 0.0 0.0 5.2 0.0 3.3 2.0 2.8 0.0 1.7 3.4 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 5.9 4.6 4.6 10.6 0.0 3.9 0.0 0.0 0.2 5.3 0.0 0.0 0.0 3.9 0.0 0.0 8.6 8.2 0.0 0.4 0.0 0.4 0.6 0.0 0.0 0.0 1.6 0.0 0.5 6.7 0.0 0.0 2.4 0.0 4.1 4.7 1.2 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 1.4 1.2 1.1 1.3 1.4 1.6 1.5 1.2 1.4 1.5 1.3 0.6 0.0 0.5 17.6 0.8 2.2 4.9 2.3 12.0 0.0 0.9 2.2 1.0 1.5 1.3 0.0 0.0 8.3 1.7 0.0 0.0 1.9 2.2 0.7 5.6 1.2 0.0 0.4 0.3 0.5 0.3 8.9 0.5 1.7 2.5 4.7 1.4 0.1 0.5 0.0 0.3 0.0 0.0 0.3 1.2 0.9 11.5 0.8 0.0 6.5 0.0 1.9 1.0 1.0 0.3 0.6 0.0 7.9 1.7 2.8 0.0 0.9 1.0 0.1 0.0 14.7 3.2 1.8 2.1 4.4 0.9 1.4 2.8 3.4 0.0 1.4 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Cardiomyocytes: 6.6;Fibroblasts: 19.7;Hepatic stellate cells: 4.6;Langerhans cells: 9.5;Melanocytes: 7.2;Suprabasal keratinocytes: 4.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2197: 259.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" 3.1 2.7 0.0 0.5 0.1 0.1 3.4 0.1 0.3 2.6 4.2 1.8 0.8 4.7 0.4 4.0 2.0 16.1 15.9 0.3 0.0 4.1 10.2 2.5 0.1 0.0 0.0 7.9 1.3 0.2 0.1 0.2 0.0 0.6 2.0 0.0 1.2 0.2 0.3 3.4 1.3 4.7 0.0 0.6 1.0 0.4 0.0 0.2 2.7 1.3 0.5 4.4 1.3 0.1 0.0 0.1 0.0 0.0 27.8 28.4 0.0 14.9 56.2 0.3 0.2 0.0 0.0 0.0 0.0 57.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.6 0.0 35.6 4.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 57.1 0.0 259.7 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.8 6.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.8 0.0 0.0 0.3 0.0 0.0 19.7 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 0.0 2.8 0.1 7.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 1.8 0.0 0.0 0.1 4.8 0.7 0.2 0.0 0.0 0.0 FAM180B LOC399888 ENSG00000196666 "Family with sequence similarity 180 member B" Q6P0A1 11 47586678-47589194 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.5;brain: 5.9;breast: 5.2;choroid plexus: 5.1;skin 1: 6.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.4;Fibroblasts: 20.4;Langerhans cells: 11.9;Melanocytes: 5.4;Peritubular cells: 4.1;Suprabasal keratinocytes: 6.3" "Cancer enhanced" "Detected in some" "melanoma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029408 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA029408: AB_10601319" "unprognostic (1.28e-2)" "unprognostic (4.99e-3)" "unprognostic (7.48e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.64e-2)" "unprognostic (1.21e-3)" "unprognostic (1.04e-1)" "unprognostic (2.69e-1)" "unprognostic (3.87e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-5)" "unprognostic (5.65e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" 6.5 0.1 0.8 0.0 2.0 0.1 5.2 5.9 1.7 0.4 5.1 0.6 0.0 0.2 0.0 0.1 0.4 0.4 0.7 0.6 0.8 0.0 0.0 0.2 0.0 1.9 1.3 0.1 0.1 0.0 0.2 0.0 1.5 0.0 0.0 0.1 1.1 0.0 1.0 6.3 0.2 0.1 1.3 0.1 0.5 0.5 1.6 0.7 4.3 2.9 0.1 0.4 0.2 2.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.0 5.9 1.7 0.6 0.8 1.9 1.3 1.5 1.3 1.6 2.6 0.8 0.0 0.0 1.0 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 20.4 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.6 11.9 0.3 2.5 0.3 5.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.0 6.3 0.1 0.3 0.0 0.0 0.0 FAM43B FLJ44952 ENSG00000183114 "Family with sequence similarity 43 member B" Q6ZT52 1 20552573-20555020 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 21.0;brain: 21.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Distal tubular cells: 3.9;Excitatory neurons: 2.6;Fibroblasts: 3.8;Inhibitory neurons: 7.5" "Cancer enhanced" "Detected in some" "glioma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.3;BJ hTERT+: 2.4;fHDF/TERT166: 4.9;Hep G2: 3.7;SCLC-21H: 4.3;SiHa: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050813 Approved Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA050813: AB_2681244" "unprognostic (1.51e-1)" "unprognostic (5.85e-2)" "unprognostic (2.80e-3)" "unprognostic (1.48e-1)" "unprognostic (5.97e-3)" "unprognostic (1.74e-1)" "unprognostic (8.33e-2)" "unprognostic (5.87e-4)" "unprognostic (1.86e-2)" "unprognostic (7.46e-2)" "unprognostic (8.85e-3)" "unprognostic (2.73e-1)" "unprognostic (1.78e-4)" "unprognostic (1.06e-2)" "unprognostic (6.05e-3)" "unprognostic (6.48e-2)" "unprognostic (2.12e-2)" 1.6 21.0 12.2 0.2 10.7 0.0 0.3 11.0 12.5 0.6 2.4 0.9 0.1 1.0 3.0 0.3 0.9 0.2 3.9 13.5 13.5 5.0 0.4 0.3 0.0 16.6 21.7 0.3 0.5 0.0 0.8 0.6 13.8 0.7 0.1 0.4 0.5 0.1 0.9 0.2 0.3 0.8 9.9 0.8 0.3 0.5 18.8 0.1 1.2 1.4 0.0 0.7 0.4 10.2 0.0 1.7 0.2 3.3 0.1 0.1 0.0 0.3 2.4 0.4 0.0 0.1 0.0 0.0 0.2 4.9 0.8 0.0 0.5 0.0 0.0 0.0 0.7 0.1 0.2 3.7 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.3 0.5 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 10.7 11.0 12.5 13.5 13.5 16.6 21.7 13.8 9.9 18.8 10.2 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.2 1.8 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.1 1.9 1.6 0.0 0.0 2.6 0.0 0.1 3.8 0.0 0.2 0.0 0.0 1.8 0.0 0.1 0.0 7.5 0.0 0.0 0.6 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.3 0.1 0.9 0.7 0.0 0.0 0.1 0.1 0.1 0.0 FAM76A MGC34648 ENSG00000009780 "Family with sequence similarity 76 member A" Q8TAV0 1 27725961-27763116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 131.5;Late spermatids: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044762, HPA077897" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA044762: AB_10795886, HPA077897: AB_2686867" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (7.58e-2)" "unprognostic (2.07e-2)" "unprognostic (2.87e-1)" "unprognostic (2.18e-3)" "unprognostic (4.44e-3)" "unprognostic (2.18e-3)" "unprognostic (3.07e-2)" "unprognostic (1.04e-1)" "unprognostic (4.35e-3)" "unprognostic (5.22e-2)" "prognostic favorable (2.26e-4)" "unprognostic (6.32e-2)" "unprognostic (6.33e-3)" "unprognostic (2.30e-1)" "unprognostic (1.07e-2)" 21.0 5.8 5.9 8.5 6.5 13.7 11.7 8.3 8.9 9.3 10.1 10.1 8.7 12.9 10.0 11.7 9.7 10.8 10.1 5.5 7.4 11.6 12.0 10.5 10.7 6.9 5.7 9.6 11.3 13.7 7.8 11.1 6.5 10.0 13.4 15.4 7.9 10.4 40.4 12.0 8.8 10.3 4.5 11.0 11.7 18.6 6.9 8.0 15.9 12.8 10.9 7.1 8.0 12.3 10.0 7.8 8.8 9.1 10.9 9.4 15.9 9.1 9.5 13.1 12.9 9.1 13.0 18.1 5.9 10.2 12.5 12.8 11.2 10.1 10.2 9.4 8.2 5.6 11.7 10.7 8.7 8.9 8.4 9.7 10.8 14.6 14.5 6.7 6.7 9.5 10.9 16.5 9.6 9.5 21.4 8.3 13.9 9.6 7.8 12.8 10.4 10.3 10.6 14.1 12.7 5.7 10.5 11.1 11.3 10.7 7.8 3.5 7.3 15.5 6.7 18.1 6.4 14.9 17.7 14.6 9.7 11.5 6.7 9.8 8.8 11.0 10.4 9.4 11.3 9.2 10.8 10.2 8.1 9.7 10.1 11.2 6.1 9.4 10.1 11.3 8.9 5.3 5.9 6.5 8.3 8.9 5.5 7.4 6.9 5.7 6.5 4.5 6.9 12.3 20.0 28.9 17.0 9.4 20.3 19.1 9.4 8.1 23.3 28.5 14.8 12.1 15.9 14.3 8.8 23.9 27.1 31.3 26.7 12.1 21.5 11.7 131.5 19.6 19.6 14.8 4.2 13.5 15.9 9.7 11.5 26.0 17.3 13.9 11.4 8.5 22.1 18.4 11.8 28.6 15.2 10.4 6.1 15.8 25.2 110.7 16.8 15.2 39.2 13.1 11.4 19.1 16.5 5.0 11.6 9.6 9.1 37.2 10.9 5.4 10.3 20.1 25.3 39.6 19.7 25.4 27.6 35.3 55.4 17.3 27.0 45.4 18.9 11.0 9.2 5.3 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FGF16 MF4 ENSG00000196468 "Fibroblast growth factor 16" O43320 X 77447389-77457278 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.8" "Cell type enhanced" "Detected in some" "Fibroblasts: 1.5;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 22.5" "Group enriched" "Detected in some" 6 "basal ganglia: 3.6;hippocampal formation: 2.0;olfactory bulb: 6.7" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.01e-2)" "unprognostic (5.30e-2)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.31e-1)" "unprognostic (6.57e-2)" "unprognostic (1.49e-2)" 0.6 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.3 0.1 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FGF18 "FGF-18, ZFGF5" ENSG00000156427 "Fibroblast growth factor 18" O76093 5 171419647-171457626 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 16.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 19.8;Cardiomyocytes: 24.4;Endometrial ciliated cells: 13.0;Glandular and luminal cells: 24.9" "Group enriched" "Detected in many" 6 "endometrial cancer: 19.0;ovarian cancer: 21.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "EFO-21: 188.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 2.3" HPA018795 Uncertain "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA018795: AB_1848523" "unprognostic (3.01e-1)" "unprognostic (2.38e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-3)" "unprognostic (6.62e-3)" "unprognostic (1.50e-1)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-3)" "unprognostic (3.65e-2)" "unprognostic (3.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.37e-8)" "unprognostic (7.33e-2)" "unprognostic (2.58e-1)" "unprognostic (3.19e-1)" "unprognostic (2.76e-2)" 4.2 0.3 1.1 0.3 1.2 0.0 2.1 1.1 2.1 1.0 1.1 0.9 0.6 0.9 0.1 0.3 1.5 0.7 16.1 1.1 1.2 0.7 0.1 2.6 0.3 1.4 1.3 0.4 0.5 0.1 1.6 0.5 1.6 1.2 0.1 0.1 1.1 0.3 3.8 1.6 0.7 0.4 1.1 0.5 0.6 0.8 1.5 0.3 1.9 0.4 0.2 0.8 0.5 1.2 0.0 0.3 0.3 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.1 3.4 0.4 0.2 188.2 0.0 0.2 0.2 0.0 0.1 0.0 3.1 0.3 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.9 0.1 3.4 0.0 0.1 0.0 0.3 2.1 0.1 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 1.5 0.1 0.5 0.0 0.2 0.6 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 1.1 2.1 1.1 1.2 1.4 1.3 1.6 1.1 1.5 1.2 6.9 6.4 0.0 0.0 2.0 2.4 2.6 0.5 6.2 0.1 6.6 19.8 24.4 1.5 1.3 1.8 0.0 0.1 3.4 0.5 0.0 0.0 6.2 13.0 3.1 4.2 1.8 0.0 0.8 0.0 0.3 9.4 0.5 24.9 0.0 0.0 2.9 0.0 0.1 0.0 2.1 1.0 0.0 0.0 2.1 0.7 0.3 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.4 0.4 3.2 1.1 0.0 0.0 0.0 0.0 5.4 4.6 0.7 1.6 5.6 3.1 0.0 2.4 0.5 1.8 0.9 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086905-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 82.5;lung: 65.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 78.6;Hepatocytes: 31.2;Skeletal myocytes: 141.2;Theca cells: 36.7;Undifferentiated cells: 38.6" "Cancer enhanced" "Detected in many" "liver cancer: 42.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CACO-2: 173.9;Hep G2: 176.4;RH-30: 274.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" NA NA 7400000 "Cluster 18: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" 1.2 14.0 1.1 4.1 1.1 0.5 4.5 2.7 2.1 3.0 1.2 18.0 21.3 2.4 0.2 3.2 4.2 10.2 2.2 1.4 1.0 40.2 82.5 65.4 0.8 0.7 0.8 27.5 29.5 0.2 2.0 2.1 0.9 5.2 6.0 1.5 1.1 0.7 6.6 1.7 20.0 1.1 0.7 22.7 8.8 5.9 1.1 0.2 0.9 1.9 0.2 6.4 3.2 1.3 3.2 48.8 1.0 11.7 0.1 0.1 24.5 0.2 0.1 0.2 0.3 173.9 6.5 5.3 23.0 0.1 2.4 2.8 9.5 1.8 0.1 3.2 13.8 0.5 2.8 176.4 5.2 0.6 4.7 1.1 0.2 8.4 0.2 0.3 0.2 3.5 18.1 0.7 3.9 40.3 0.1 3.6 29.2 30.9 4.5 8.2 274.3 30.9 22.9 0.4 1.8 2.9 1.8 12.4 5.9 5.9 11.7 2.5 1.1 0.0 23.4 0.3 0.7 1.6 1.9 3.7 0.1 1.1 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.1 1.1 2.7 2.1 1.4 1.0 0.7 0.8 0.9 0.7 1.1 1.3 0.3 0.0 0.0 0.3 0.3 0.6 0.7 0.4 0.0 0.9 2.9 2.0 0.9 78.6 0.1 3.7 0.0 1.3 0.1 12.9 3.9 10.9 0.1 1.6 0.3 0.7 4.2 0.0 0.5 4.9 3.8 9.6 9.7 2.9 0.0 0.7 3.9 31.2 0.3 0.0 0.5 10.1 0.0 0.9 0.5 0.0 0.6 0.7 0.0 1.9 0.6 0.6 0.0 0.5 0.1 3.0 4.4 1.5 0.1 1.7 15.9 21.6 0.1 0.4 19.7 141.2 0.7 3.0 9.9 0.8 0.4 8.8 0.4 36.7 38.6 0.5 FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99830141-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 210.1;Early spermatids: 376.7;Sertoli cells: 256.4;Skeletal myocytes: 184.2;Smooth muscle cells: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 4 "dendritic cells: 2.1;monocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 84.2;HDLM-2: 79.9;TIME: 145.8" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA043133: AB_10793991" "unprognostic (9.14e-2)" "unprognostic (2.16e-1)" "unprognostic (7.73e-2)" "unprognostic (5.25e-2)" "unprognostic (6.68e-2)" "unprognostic (1.06e-2)" "unprognostic (4.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (2.46e-2)" "unprognostic (9.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-3)" 77.1 21.7 4.9 52.4 6.3 0.8 32.6 4.8 6.6 63.8 4.0 57.7 28.4 117.6 23.8 56.0 31.2 90.9 54.8 6.2 4.4 24.0 28.1 30.7 30.1 9.6 4.2 76.4 35.5 17.5 3.9 43.9 9.7 67.9 29.8 4.7 9.3 54.3 140.4 16.8 41.2 151.7 3.7 42.9 46.7 22.0 3.6 11.9 20.1 161.5 22.3 101.5 21.9 4.0 59.0 0.0 22.3 0.1 35.8 30.2 2.0 29.4 58.8 50.2 56.5 17.8 0.2 0.2 5.0 84.2 13.2 7.1 0.0 14.4 59.0 79.9 0.6 4.8 0.2 23.3 17.8 1.4 0.0 24.2 5.1 5.6 0.0 32.0 22.8 0.0 3.8 0.5 7.7 0.1 5.2 1.2 1.3 3.1 0.0 0.1 26.1 0.7 33.5 1.0 2.0 3.7 0.4 0.4 0.1 11.7 0.0 10.5 145.8 8.8 0.2 1.9 15.5 4.2 0.2 0.3 6.5 0.4 0.0 0.2 0.4 0.0 0.1 1.0 0.0 0.6 0.1 0.1 2.1 0.6 0.0 0.1 0.2 0.4 2.9 0.4 0.1 0.3 4.9 6.3 4.8 6.6 6.2 4.4 9.6 4.2 9.7 3.7 3.6 4.0 92.9 16.0 23.1 9.4 4.1 27.8 56.7 7.9 2.2 11.8 12.3 6.5 145.7 35.8 2.3 5.5 8.4 1.1 1.8 2.1 1.9 210.1 376.7 2.3 60.5 77.2 3.0 0.0 42.0 109.3 0.7 145.2 21.9 2.4 34.8 16.3 41.0 0.7 3.2 106.0 25.8 5.7 6.1 36.3 98.9 180.2 83.0 86.1 17.8 25.3 17.7 0.9 0.0 22.1 21.6 43.7 0.2 104.2 3.0 5.1 5.4 2.6 1.9 6.0 256.4 184.2 351.9 40.1 2.5 1.5 22.7 3.1 8.8 41.8 3.2 3.5 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 14.2;thyroid gland: 20.3" "Group enriched" "Detected in some" 4 "Fibroblasts: 28.7;Smooth muscle cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 5.4;hippocampal formation: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;fHDF/TERT166: 2.9;SuSa: 3.1" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" NA NA 14000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" 5.4 0.5 0.5 1.9 0.3 0.0 2.1 0.1 5.4 6.5 0.2 12.9 2.5 2.2 0.0 1.1 0.6 14.2 3.9 8.7 0.3 0.6 0.7 1.6 2.8 0.1 1.0 1.2 1.1 0.3 0.2 0.9 0.0 0.4 1.8 0.1 0.9 0.8 2.1 0.9 4.2 11.7 0.3 0.5 0.4 0.4 0.4 0.1 20.3 9.6 2.4 1.0 1.6 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 5.4 8.7 0.3 0.1 1.0 0.0 0.3 0.4 1.2 2.6 0.0 0.6 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.1 0.5 2.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.3 0.4 4.7 0.7 0.0 0.0 0.2 0.0 0.2 28.7 0.0 0.3 0.0 0.1 1.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 3.1 0.0 0.3 0.2 1.8 2.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 3.0 11.5 1.1 1.4 0.0 1.4 0.1 0.5 0.1 0.0 0.0 FNDC5 FRCP2 ENSG00000160097 "Fibronectin type III domain containing 5" Q8NAU1 1 32862268-32872482 "Predicted membrane proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 323.1;tongue: 478.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 71.3;Cardiomyocytes: 64.9;Early spermatids: 28.1;Granulosa cells: 38.6;Muller glia cells: 44.1" "Group enriched" "Detected in many" 7 "glioma: 4.2;liver cancer: 10.0;testis cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "RH-30: 48.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051290 Enhanced "Intracellular and membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "HPA051290: AB_2681422" "unprognostic (4.36e-2)" "unprognostic (9.08e-3)" "unprognostic (7.62e-4)" "unprognostic (1.03e-2)" "unprognostic (3.77e-2)" "unprognostic (6.26e-2)" "unprognostic (5.68e-2)" "unprognostic (2.76e-2)" "unprognostic (1.45e-2)" "unprognostic (1.83e-1)" "unprognostic (3.15e-3)" "unprognostic (1.63e-1)" "unprognostic (9.07e-2)" "unprognostic (7.07e-3)" "unprognostic (1.13e-1)" "unprognostic (3.37e-3)" "unprognostic (1.33e-2)" 1.3 12.8 10.5 0.1 5.8 0.2 0.8 21.6 10.0 1.4 47.6 1.3 0.8 3.3 2.4 11.6 4.1 1.8 42.2 6.7 16.8 0.7 18.4 1.1 0.2 10.5 14.7 4.6 0.5 10.4 5.2 0.5 7.6 3.6 0.5 8.0 25.5 1.0 323.1 0.4 1.3 2.0 5.3 0.2 5.2 2.7 29.6 0.6 1.2 478.4 0.1 1.2 0.8 3.3 0.0 0.1 1.1 0.4 0.0 1.2 0.2 0.5 0.1 0.7 0.1 0.9 0.3 0.2 0.8 0.4 0.2 0.1 4.7 0.1 0.1 0.1 0.3 0.1 0.4 0.2 0.0 0.2 0.0 1.8 0.0 0.3 0.0 0.6 0.0 0.2 0.9 0.1 0.8 0.1 0.1 0.1 1.4 0.0 0.1 0.6 48.2 0.3 0.0 0.1 6.9 1.1 0.5 0.0 0.0 0.5 0.2 0.1 0.2 0.1 0.8 2.2 0.4 0.2 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 5.8 21.6 10.0 6.7 16.8 10.5 14.7 7.6 5.3 29.6 3.3 1.1 0.0 0.0 7.5 0.0 0.1 0.2 0.0 0.0 71.3 0.6 0.5 64.9 0.0 0.0 1.8 4.2 0.0 0.0 0.0 1.9 0.0 28.1 0.3 4.6 1.4 0.0 0.0 10.3 0.0 0.0 14.5 0.0 0.5 0.0 38.6 0.7 2.0 0.9 0.0 15.8 0.1 0.0 0.0 0.5 5.9 5.3 0.8 0.0 5.6 0.0 44.1 0.0 3.0 0.7 0.1 0.0 5.7 0.0 0.2 0.1 0.2 0.0 7.4 0.0 12.9 1.7 0.5 1.0 0.0 0.0 0.3 0.2 0.5 0.5 0.1 FOS "AP-1, c-fos" ENSG00000170345 "Fos proto-oncogene, AP-1 transcription factor subunit" P01100 14 75278826-75282230 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 504.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 504.8" "Cell line enhanced" "Detected in many" "hTCEpi: 453.1;OE19: 170.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebellum: 80.9;spinal cord: 235.3" HPA018531 Approved Supported Nucleoplasm Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA018531: AB_1846576" "unprognostic (1.18e-2)" "unprognostic (8.70e-2)" "unprognostic (1.61e-1)" "unprognostic (3.80e-1)" "unprognostic (3.08e-2)" "unprognostic (4.82e-2)" "unprognostic (2.09e-1)" "unprognostic (3.30e-1)" "unprognostic (9.55e-3)" "unprognostic (4.20e-3)" "unprognostic (1.04e-1)" "prognostic favorable (7.81e-4)" "unprognostic (3.20e-2)" "unprognostic (1.52e-2)" "unprognostic (3.22e-1)" "unprognostic (1.43e-1)" "unprognostic (2.66e-2)" 1136.1 735.7 62.9 576.0 87.2 2270.6 477.4 184.8 113.1 700.5 111.5 479.5 235.3 410.4 58.4 1250.8 1777.3 1160.0 513.1 58.9 190.7 266.1 308.8 486.9 449.9 145.1 84.0 1188.7 298.4 264.7 452.3 417.4 92.0 791.1 627.4 233.3 555.6 462.3 99.1 1645.4 584.5 964.3 100.6 178.0 525.6 87.2 104.4 424.2 1007.6 1014.2 26.8 946.5 346.6 121.7 2.2 1.4 7.1 10.4 59.9 18.3 42.1 6.4 2.4 4.5 3.2 4.4 12.6 0.6 1.8 43.5 42.6 3.0 3.6 74.7 1.1 1.2 1.1 1.0 21.9 1.9 27.6 2.6 42.8 44.3 453.1 3.9 27.4 6.2 2.7 9.2 2.0 19.7 1.2 26.1 0.9 12.9 7.4 170.9 2.5 2.0 1.4 23.8 18.8 20.4 52.4 3.6 9.8 85.9 39.8 21.8 1.4 9.2 6.3 0.4 5.7 3.7 2.0 52.4 61.2 9.6 2.9 8.0 5.7 38.3 81.0 89.5 0.3 20.1 0.4 0.3 0.2 0.7 69.6 0.2 0.2 0.1 504.8 4.6 2.5 1.5 0.4 27.7 62.9 87.2 184.8 113.1 58.9 190.7 145.1 84.0 92.0 100.6 104.4 121.7 3911.0 1102.6 1859.4 137.1 1015.9 859.7 1644.7 1577.5 4336.7 106.1 3184.1 2874.6 1027.6 1416.9 752.7 191.3 129.3 1506.7 1323.5 1648.6 17.6 690.9 17.4 1834.4 3720.3 1624.0 1628.0 290.5 4.9 528.1 2694.6 4146.8 2049.5 3656.5 1630.6 751.3 1317.2 207.2 1693.8 35.3 3.0 1967.2 793.5 2600.2 1540.4 53.5 943.8 2910.7 855.6 58.1 269.5 1119.5 10.3 6.0 1.8 383.5 1507.8 178.3 1256.1 1115.7 1675.1 20.0 354.4 406.9 1209.6 3390.9 2705.7 10.0 10.5 2438.0 1092.4 2283.3 1497.0 417.4 1366.2 298.4 FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.1;Fibroblasts: 521.9;Leydig cells: 327.4;Peritubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 1782.4;BJ: 2156.3;fHDF/TERT166: 2692.9;HBF TERT88: 1741.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" 432.4 134.3 20.5 116.3 18.1 2.2 166.1 22.8 22.7 279.9 83.0 156.4 37.1 157.5 50.8 126.1 150.6 257.0 242.7 20.6 22.8 45.4 35.7 120.7 50.3 28.5 44.6 90.3 37.3 35.5 25.7 442.0 23.1 188.3 90.4 29.8 59.3 184.4 31.8 64.2 69.1 409.6 22.7 63.1 68.6 33.5 22.7 24.2 78.8 89.8 38.8 260.4 104.3 20.6 81.0 21.2 222.9 91.8 1304.4 1782.4 1.3 2156.3 1208.9 1374.5 1211.0 0.1 178.5 0.8 178.8 2692.9 112.8 20.5 68.6 270.0 1741.5 1.1 32.5 0.4 159.8 0.3 286.0 1.2 0.9 1362.7 8.5 884.5 192.7 612.1 811.6 11.2 0.5 0.3 227.6 0.5 22.6 2.0 181.3 0.4 181.9 0.7 92.7 1.0 150.4 1.7 39.2 93.5 764.6 13.6 76.5 462.6 23.5 6.2 986.8 507.4 479.8 268.0 323.8 1.0 1.1 2.3 177.4 0.9 67.0 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 2.6 20.5 18.1 22.8 22.7 20.6 22.8 28.5 44.6 23.1 22.7 22.7 20.6 76.9 64.1 9.4 56.5 1.1 64.1 31.9 36.4 10.2 2.3 25.6 24.6 127.5 8.6 42.5 23.9 0.0 114.4 2.5 0.9 0.0 62.6 2.3 44.4 176.7 111.4 3.0 3.6 9.6 5.8 352.1 521.9 3.1 23.0 1.3 66.5 142.5 17.4 20.6 1.7 16.2 0.2 8.2 10.8 91.6 9.8 327.4 11.5 110.3 30.0 9.9 116.1 0.0 9.5 0.9 117.8 0.7 270.8 0.9 108.4 0.0 5.5 74.9 4.3 59.2 62.5 129.3 1.5 4.4 2.2 48.2 54.7 7.1 47.5 0.9 65.3 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.9;Astrocytes: 34.6;Early spermatids: 26.6;Endothelial cells: 26.9;Hepatic stellate cells: 41.7;Muller glia cells: 47.4;Oligodendrocytes: 69.3" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 133.0;ASC TERT1: 128.8;HSkMC: 102.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 157.4 4.9 45.1 1.7 55.8 2.7 87.2 62.5 49.3 12.3 14.4 21.7 3.0 11.4 11.9 12.4 24.9 5.6 18.1 47.9 90.8 11.8 4.0 9.4 4.1 137.6 60.4 22.3 3.6 2.4 3.5 32.3 130.8 6.0 3.9 13.4 25.5 4.7 36.3 41.7 21.2 7.0 102.4 12.3 15.3 9.1 62.8 4.0 18.3 35.3 1.3 33.0 22.8 141.7 0.4 1.3 0.9 1.0 133.0 128.8 0.3 3.4 2.5 0.4 1.3 0.0 0.5 0.5 1.9 7.8 2.3 0.8 0.5 1.4 2.0 0.6 1.4 1.1 1.9 0.0 7.4 1.5 0.4 102.8 0.0 1.2 1.8 2.4 2.8 0.7 0.2 3.0 1.1 1.9 0.0 2.1 0.5 0.8 1.1 0.3 1.1 24.1 0.5 0.5 0.4 0.3 0.4 1.0 0.6 0.6 0.7 1.8 3.9 0.6 4.3 26.8 0.6 1.4 5.1 1.4 2.5 0.4 0.4 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 45.1 55.8 62.5 49.3 47.9 90.8 137.6 60.4 130.8 102.4 62.8 141.7 103.9 0.0 1.7 34.6 0.1 0.5 0.4 0.0 0.0 3.8 1.1 0.9 2.8 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 26.6 0.5 3.3 26.9 0.0 0.0 4.9 0.0 0.1 24.7 0.0 1.0 1.3 0.1 41.7 1.8 0.1 0.0 3.9 0.0 0.0 0.8 2.1 16.7 1.8 0.5 0.0 22.5 0.1 47.4 0.0 5.0 69.3 0.2 0.0 0.7 1.8 2.1 0.0 0.1 0.0 3.2 0.0 7.3 2.1 25.5 0.5 0.1 0.9 0.0 0.2 0.3 0.0 0.3 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.8;heart muscle: 45.0" "Cell type enhanced" "Detected in many" "Astrocytes: 16.6;Cardiomyocytes: 46.7;Excitatory neurons: 27.6;Fibroblasts: 24.0;Inhibitory neurons: 23.8;Smooth muscle cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.5;ASC diff: 11.7;hTEC/SVTERT24-B: 17.0;hTERT-RPE1: 17.2;SCLC-21H: 8.7;U-2 OS: 19.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059136, HPA075325" Approved Approved Vesicles,Cytosol NA NA 370000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA059136: AB_2683919, HPA075325: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favorable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 14.4 11.6 25.7 2.0 24.4 0.1 12.0 14.7 28.4 7.6 6.5 6.5 2.2 7.3 2.8 3.6 5.6 3.4 45.0 27.0 35.5 7.7 2.0 3.4 3.2 19.6 22.5 2.1 4.3 2.5 4.7 0.4 19.9 4.0 2.2 1.3 23.5 4.6 4.4 7.5 3.7 8.6 16.4 12.1 3.2 3.5 40.8 2.2 4.9 5.8 1.3 3.1 5.0 21.3 0.0 0.8 8.5 0.3 11.7 5.3 0.0 1.3 0.1 1.5 2.3 0.4 0.0 0.0 0.2 1.4 0.8 0.0 3.0 0.0 0.3 0.1 6.0 0.0 0.2 0.5 0.1 0.0 0.5 0.5 0.0 17.0 0.0 17.2 0.9 0.0 0.0 0.0 2.8 0.5 0.0 0.0 1.7 0.0 0.1 0.0 4.8 0.0 0.5 0.0 8.7 3.0 1.8 0.4 0.0 0.3 0.3 0.0 0.1 1.7 19.9 2.2 2.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 24.4 14.7 28.4 27.0 35.5 19.6 22.5 19.9 16.4 40.8 21.3 4.0 0.0 0.0 16.6 0.0 4.1 0.4 0.0 0.0 2.8 3.1 3.0 46.7 0.0 0.0 0.0 2.1 0.1 0.2 0.0 3.9 0.1 9.7 0.2 0.4 1.7 0.0 0.0 27.6 0.0 0.0 24.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 23.8 0.1 0.0 0.0 6.1 11.2 0.9 0.3 3.6 5.6 0.0 0.1 0.0 8.0 1.6 0.0 0.0 3.8 0.0 0.5 0.1 0.1 0.0 0.8 6.6 10.1 14.8 0.6 2.1 0.3 3.3 0.0 0.3 11.2 0.6 0.4 GAS1 ENSG00000180447 "Growth arrest specific 1" P54826 9 86944362-86947506 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 105.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 127.1;Muller glia cells: 90.3;Skeletal myocytes: 213.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 30.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.2;ASC diff: 29.3;BJ hTERT+: 59.8;HSkMC: 41.1;RH-30: 91.1" "Low region specificity" "Detected in all" "CAB024164, HPA036085, HPA066902" Approved Approved "Nuclear speckles" NA NA 27000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "CAB024164: AB_2107950, HPA036085: AB_2674932, HPA066902: AB_2685746" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.97e-2)" "unprognostic (6.15e-2)" "unprognostic (2.84e-2)" "unprognostic (6.46e-2)" "unprognostic (6.91e-2)" "unprognostic (3.32e-1)" "unprognostic (1.28e-3)" "unprognostic (2.25e-3)" "unprognostic (4.30e-2)" "prognostic unfavorable (1.96e-5)" "prognostic unfavorable (8.26e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.13e-5)" "unprognostic (3.59e-2)" 81.5 6.4 3.6 16.6 4.4 0.2 38.3 3.5 4.4 27.1 16.1 27.6 2.2 105.4 15.2 5.8 60.7 10.5 27.1 3.2 2.7 12.5 2.2 7.8 6.8 3.8 3.8 45.1 11.2 1.9 8.4 22.1 3.6 22.6 2.3 3.3 13.1 9.6 12.2 22.2 9.3 43.4 3.4 3.6 16.3 1.8 3.8 7.1 15.9 9.3 3.1 22.5 27.1 6.8 0.0 0.0 7.5 44.2 29.3 10.9 0.8 8.8 59.8 2.9 2.6 0.0 0.1 0.0 0.5 15.8 0.3 0.6 0.0 0.3 1.2 5.2 17.8 0.0 25.0 0.0 14.9 0.1 0.7 41.1 6.3 1.0 5.3 0.0 0.0 0.9 0.0 0.0 12.6 0.0 0.0 0.4 9.5 0.3 0.1 9.6 91.1 0.0 0.4 0.0 1.0 4.0 12.9 0.0 14.1 4.8 0.1 0.2 0.1 13.0 3.6 0.9 3.0 0.0 0.0 0.0 0.4 0.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.4 3.5 4.4 3.2 2.7 3.8 3.8 3.6 3.4 3.8 6.8 15.8 0.0 0.6 2.0 0.4 25.9 7.5 10.9 10.2 8.3 3.9 28.3 5.5 0.0 3.1 14.7 10.4 21.5 7.8 0.1 9.8 0.5 0.1 2.4 36.6 5.6 0.0 0.4 1.2 0.4 3.7 127.1 1.1 2.0 0.0 2.1 22.9 0.3 5.8 5.0 2.6 0.3 0.0 1.0 15.4 0.9 32.3 2.2 17.8 1.9 0.2 90.3 7.2 8.5 4.4 0.2 0.0 12.4 2.1 4.5 0.0 2.6 0.7 3.2 39.5 213.7 15.4 0.3 1.3 1.0 12.5 4.5 2.1 0.8 0.2 0.4 GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 348.3;Sertoli cells: 322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.7" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.7" "Cell line enhanced" "Detected in many" "BJ: 347.0;BJ hTERT+: 494.0;HSkMC: 281.3;RPMI-8226: 493.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" NA NA 8900000 3600000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Centriolar satellite" "HPA008275: AB_1849497, HPA056080: AB_2683032" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-3)" "unprognostic (1.37e-1)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (4.81e-3)" "unprognostic (1.97e-1)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "prognostic unfavorable (8.93e-6)" 124.2 32.5 26.7 18.8 28.7 3.6 77.4 33.9 32.0 244.4 59.3 67.8 48.7 171.7 13.8 63.2 161.3 58.9 169.1 24.1 34.6 72.7 37.1 97.3 22.5 37.4 36.1 118.0 49.9 58.5 58.4 51.6 38.5 100.9 25.2 6.3 84.4 63.8 99.2 101.4 47.8 57.9 30.8 29.4 70.0 60.1 34.1 39.6 101.2 67.5 10.6 127.0 172.0 25.2 151.3 6.6 4.4 3.8 169.5 94.0 18.4 347.0 494.0 141.3 168.4 9.6 71.0 1.4 11.4 157.2 24.9 139.1 2.4 77.7 35.6 0.2 20.1 1.1 11.1 1.0 120.8 1.0 2.1 281.3 44.9 39.1 39.0 243.2 5.3 2.3 2.6 79.9 231.9 7.4 0.8 1.5 9.5 24.0 9.9 4.5 0.1 493.5 51.9 1.9 23.5 21.3 38.3 1.3 0.4 23.8 45.9 119.4 81.7 36.9 45.0 4.4 100.5 0.1 8.0 1.5 41.9 3.6 5.8 0.0 1.4 0.0 0.0 1.1 0.0 0.1 0.2 0.0 11.3 0.1 0.0 0.0 0.0 0.1 0.3 70.7 0.0 1.4 26.7 28.7 33.9 32.0 24.1 34.6 37.4 36.1 38.5 30.8 34.1 25.2 133.2 198.7 25.9 23.2 20.8 84.4 94.7 18.5 70.0 38.0 17.9 114.3 86.8 50.1 23.4 31.3 0.0 1.8 59.1 92.4 27.4 45.7 5.1 35.2 33.1 71.9 10.3 5.3 26.2 6.7 1.9 152.7 19.9 32.3 8.2 154.7 159.9 21.6 101.6 348.3 31.9 69.5 8.2 22.3 100.4 8.9 92.2 48.6 122.7 41.2 9.8 32.7 0.0 3.0 7.5 24.1 58.6 59.5 147.4 30.5 84.1 0.6 15.5 12.5 322.1 22.9 121.1 5.3 17.6 27.6 71.9 2.9 4.7 214.8 151.4 31.1 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.4;Extravillous trophoblasts: 2.6;Fibroblasts: 1.8;Hofbauer cells: 3.9;Syncytiotrophoblasts: 2.7" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;RPMI-8226: 3.4;SK-BR-3: 2.6;T-47d: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" 5.5 2.1 4.9 2.5 6.4 0.0 4.2 6.3 3.8 10.6 4.9 3.4 0.7 9.8 2.2 1.8 11.3 5.3 1.7 4.1 5.9 1.0 13.1 3.1 0.7 8.8 7.7 6.8 2.0 0.1 3.0 2.0 7.6 2.6 1.0 3.9 2.6 2.2 1.4 1.7 2.1 6.0 6.3 0.9 3.4 2.9 10.0 0.6 2.1 0.8 0.3 3.2 3.9 5.2 0.0 0.0 0.0 3.1 0.1 0.0 1.1 0.2 0.3 0.0 0.0 0.1 0.9 0.0 1.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.6 0.4 1.2 0.8 0.0 0.4 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 0.0 3.4 0.0 0.5 0.1 0.3 0.0 2.6 0.0 0.1 6.7 0.9 0.0 0.4 0.6 1.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 6.4 6.3 3.8 4.1 5.9 8.8 7.7 7.6 6.3 10.0 5.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 30.4;Fibroblasts: 77.9;Skeletal myocytes: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cell line enhanced" "Detected in many" "ASC diff: 119.1;ASC TERT1: 202.3;GAMG: 152.5;HSkMC: 130.7;hTEC/SVTERT24-B: 248.0;U-87 MG: 426.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" 112.4 7.0 14.2 18.6 14.8 0.1 23.0 19.7 17.6 24.8 14.1 18.0 1.6 15.9 7.7 5.7 35.8 16.4 27.8 14.9 16.8 6.8 2.1 25.2 2.8 27.8 15.7 33.4 12.4 4.6 5.1 6.5 21.5 15.6 3.2 2.9 7.1 8.2 4.6 8.4 11.3 11.3 16.8 1.9 14.6 8.6 15.7 1.2 10.8 7.1 3.5 38.3 17.9 20.4 0.1 27.7 21.5 28.0 119.1 202.3 2.3 3.5 0.7 2.3 0.8 0.7 0.1 0.0 1.4 23.2 152.5 0.4 11.8 0.2 1.4 2.6 4.2 0.0 13.7 0.0 49.4 0.0 0.2 130.7 1.0 248.0 0.7 41.7 40.7 1.0 0.0 0.4 107.7 4.2 0.1 0.0 45.7 0.3 12.3 0.6 0.2 0.0 0.0 0.0 1.0 1.6 43.0 0.8 1.4 25.0 1.9 0.3 19.5 67.9 10.7 44.3 52.2 0.1 0.1 0.0 426.7 0.0 1.5 0.0 0.0 0.0 0.7 0.0 3.5 0.0 0.3 1.2 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 14.2 14.8 19.7 17.6 14.9 16.8 27.8 15.7 21.5 16.8 15.7 20.4 4.1 3.2 4.8 13.4 0.8 7.4 0.4 0.2 3.4 0.0 3.2 6.3 3.0 5.7 3.2 1.8 0.0 1.1 3.5 0.4 1.9 1.0 5.7 2.0 30.4 1.9 0.0 0.0 20.0 0.8 0.5 77.9 6.6 1.9 1.3 0.4 1.4 0.0 0.5 0.0 12.1 0.5 0.0 0.3 9.6 3.5 10.2 1.7 8.8 4.7 0.0 6.1 0.0 10.6 6.5 0.4 0.0 18.8 2.5 1.7 0.0 0.4 1.5 0.1 0.0 27.3 17.6 10.1 8.3 1.7 4.3 2.7 8.9 0.0 0.1 0.6 GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116273284 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 40.5;Breast glandular cells: 33.1;Fibroblasts: 51.2;Hepatocytes: 42.2;Oligodendrocyte precursor cells: 91.0;Skeletal myocytes: 100.1" "Cancer enriched" "Detected in many" 11 "breast cancer: 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 44.7;BJ hTERT+ SV40 Large T+ RasG12V: 77.2;EFO-21: 46.5;fHDF/TERT166: 89.3;HBF TERT88: 63.2;MCF7: 59.5;U-251 MG: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA043829: AB_2678689" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (7.60e-2)" "unprognostic (1.06e-3)" "unprognostic (4.10e-2)" "unprognostic (6.95e-3)" "unprognostic (2.35e-3)" "unprognostic (1.48e-3)" "unprognostic (3.16e-1)" "unprognostic (2.06e-3)" "unprognostic (1.31e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (3.64e-2)" 10.9 3.4 7.2 4.2 14.9 0.0 23.2 2.6 9.5 9.9 0.3 18.3 1.7 4.9 20.5 6.9 17.2 5.6 4.8 9.7 18.0 6.0 16.0 2.8 4.0 7.8 28.5 4.5 6.6 2.7 3.2 0.0 7.2 4.5 3.9 3.2 6.0 5.4 4.3 7.2 8.2 4.8 6.2 3.9 8.2 3.1 7.6 4.1 2.8 13.9 6.4 7.0 9.2 6.1 0.1 3.7 12.2 0.0 0.0 0.1 0.0 7.9 0.4 44.7 77.2 0.0 0.0 0.0 46.5 89.3 0.0 0.0 0.1 0.0 63.2 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 2.5 0.0 11.5 0.0 3.9 0.0 9.1 0.0 0.0 5.6 59.5 7.6 0.0 5.0 0.0 0.0 0.0 1.9 0.0 5.0 0.0 1.6 0.1 0.0 0.0 0.1 2.1 0.4 0.0 0.4 0.0 0.4 0.1 53.5 0.0 0.0 0.1 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 14.9 2.6 9.5 9.7 18.0 7.8 28.5 7.2 6.2 7.6 6.1 6.1 0.0 0.0 40.5 0.5 5.7 0.0 0.0 1.8 4.1 33.1 11.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 13.2 0.0 0.2 3.2 6.0 0.0 5.1 13.5 0.0 51.2 3.1 0.0 6.3 0.1 0.4 42.2 0.0 0.0 6.6 0.0 0.0 1.0 9.6 12.8 8.1 1.0 5.4 1.9 0.0 12.6 0.0 91.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.5 0.0 100.1 16.7 0.1 10.4 0.7 4.5 0.0 0.7 0.1 0.0 0.2 GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 39.5;Fibroblasts: 10.4;Leydig cells: 25.1;Peritubular cells: 30.9;Skeletal myocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.1;hTEC/SVTERT24-B: 13.1;U-2 OS: 17.9;WM-115: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" 1.6 1.0 1.9 0.9 2.2 0.0 1.4 1.4 1.3 4.3 0.6 3.4 0.4 4.7 1.2 0.8 2.8 2.1 2.3 1.1 1.9 1.4 0.4 2.0 0.3 2.1 2.1 10.9 0.3 0.1 1.8 0.8 1.8 2.9 0.6 0.0 1.4 1.1 0.9 2.7 1.6 1.9 1.6 0.8 1.6 2.4 1.8 1.3 1.0 0.4 0.3 3.1 2.4 0.9 0.0 10.3 20.1 5.5 3.2 4.0 0.0 5.8 1.8 2.4 2.4 0.0 0.5 0.0 0.9 5.2 0.9 0.3 4.3 0.2 1.9 0.0 2.1 0.4 6.1 0.2 3.8 0.0 1.2 2.3 0.0 13.1 0.0 2.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 10.6 1.6 4.3 0.1 2.2 3.5 0.0 0.0 2.0 2.1 3.8 0.0 0.2 4.3 0.1 0.0 5.1 0.0 17.9 2.5 0.0 0.0 0.1 0.0 7.4 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.2 1.4 1.3 1.1 1.9 2.1 2.1 1.8 1.6 1.8 0.9 0.3 0.0 0.0 39.5 0.0 2.0 0.1 0.5 0.6 0.0 0.1 0.9 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.1 0.3 6.1 0.5 0.0 0.0 0.7 0.2 0.1 10.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 1.5 2.1 25.1 0.1 0.0 2.8 0.0 0.0 1.0 3.0 0.3 1.0 0.0 30.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 16.0 3.4 0.1 3.6 0.1 1.7 0.0 0.0 7.9 0.0 0.1 GLIS2 NPHP7 ENSG00000126603 "GLIS family zinc finger 2" Q9BZE0 16 4314761-4339597 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 22.1;Peritubular cells: 33.8;Proximal tubular cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062755, HPA065406" Enhanced Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA062755: , HPA065406: " "unprognostic (2.86e-1)" "unprognostic (3.27e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.59e-5)" "unprognostic (3.76e-1)" "unprognostic (5.15e-2)" "unprognostic (8.13e-2)" "unprognostic (6.65e-2)" "unprognostic (3.94e-1)" "unprognostic (2.37e-3)" "unprognostic (3.59e-1)" "unprognostic (2.48e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.59e-3)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (4.40e-3)" 16.3 23.4 4.4 2.5 4.1 0.1 11.4 5.2 3.9 22.3 3.3 19.2 1.5 20.9 0.7 4.9 17.3 5.6 30.9 3.1 3.8 41.5 3.2 30.6 1.6 5.6 5.6 27.5 13.2 2.3 18.9 4.4 4.3 21.7 0.4 0.7 9.8 4.0 3.0 7.1 7.4 3.3 4.4 4.5 11.9 5.3 5.5 0.2 19.4 0.4 0.5 20.2 11.4 2.5 6.1 12.3 2.0 4.8 1.5 7.2 4.3 6.1 5.3 2.3 1.6 3.2 5.1 0.0 10.8 6.0 2.2 3.7 1.2 5.6 0.1 8.9 0.3 0.0 10.9 1.9 6.9 0.0 0.9 4.1 1.2 1.9 0.9 2.6 1.9 0.1 0.5 2.0 1.3 4.0 0.0 1.2 4.6 0.7 2.2 11.7 2.6 6.7 0.4 0.0 0.9 4.6 6.1 2.9 1.7 0.6 8.2 1.0 3.2 3.2 6.0 36.8 1.9 1.4 0.9 1.5 1.4 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 4.1 5.2 3.9 3.1 3.8 5.6 5.6 4.3 4.4 5.5 2.5 4.8 16.0 9.8 8.5 0.0 5.6 5.4 8.7 1.8 10.6 3.5 2.4 5.9 15.7 5.6 12.9 4.2 0.9 0.1 0.0 19.6 11.8 0.2 1.8 9.0 6.9 0.0 0.0 2.1 8.3 0.9 18.3 0.5 2.1 0.0 2.6 6.8 0.7 0.4 6.7 3.2 0.2 2.0 0.3 6.1 0.9 22.1 0.8 3.6 5.6 1.0 10.4 0.0 4.0 1.3 10.3 0.0 33.8 0.0 5.1 0.0 21.7 3.1 7.3 0.0 8.2 14.6 0.2 3.4 0.7 2.8 1.1 0.7 0.1 0.0 2.8 GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.3;Early spermatids: 41.2;Fibroblasts: 55.9;Leydig cells: 55.9;Peritubular cells: 51.9;Skeletal myocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 69.3;BJ hTERT+: 89.4;HSkMC: 63.2;hTERT-RPE1: 51.9;RPTEC TERT1: 45.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: AB_1849731, HPA070791: " "unprognostic (4.02e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (9.53e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (2.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.58e-6)" "prognostic unfavorable (7.92e-4)" "unprognostic (7.15e-2)" "unprognostic (7.70e-3)" "unprognostic (7.03e-3)" 16.9 10.9 4.2 5.2 4.9 1.5 19.5 2.6 5.1 29.6 11.2 17.6 5.8 27.4 21.6 7.5 22.3 35.8 15.4 4.8 3.7 4.3 2.7 10.2 6.0 2.9 3.1 41.6 4.5 6.6 9.6 9.4 3.1 13.3 11.4 1.0 7.7 16.0 3.2 4.1 7.7 21.8 2.8 1.6 8.4 6.8 3.7 2.2 26.3 11.5 5.8 20.8 18.9 4.4 0.3 0.6 0.7 22.2 28.3 69.3 0.5 32.0 89.4 8.3 10.5 0.4 0.2 0.9 1.8 37.5 0.4 0.1 0.4 11.9 7.0 1.6 10.0 0.6 11.2 0.2 12.7 0.9 0.5 63.2 0.7 10.0 13.8 51.9 4.4 0.6 0.4 1.3 36.5 0.3 0.8 0.5 2.7 0.1 6.7 1.0 33.6 0.2 45.5 0.4 1.3 1.7 33.5 0.8 0.4 2.4 6.0 0.5 0.7 13.2 6.2 1.3 1.9 3.9 0.8 0.3 1.0 0.7 1.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.2 4.9 2.6 5.1 4.8 3.7 2.9 3.1 3.1 2.8 3.7 4.4 8.0 0.0 4.6 2.9 0.3 2.8 4.2 2.4 0.0 0.8 1.0 26.3 3.9 1.5 0.1 0.0 2.1 4.1 0.4 0.0 0.0 0.1 41.2 0.6 8.3 7.5 1.8 0.0 10.2 0.0 0.8 55.9 1.1 0.4 0.0 0.1 20.7 0.3 0.6 0.0 10.5 1.3 0.0 0.6 2.8 11.5 55.9 0.4 3.6 4.7 0.6 0.5 0.0 1.0 2.6 0.3 0.0 51.9 1.2 1.4 0.0 0.0 0.1 0.5 6.6 25.2 18.0 1.1 1.1 0.2 2.4 1.4 0.6 10.7 0.0 0.1 GNPDA2 SB52 ENSG00000163281 "Glucosamine-6-phosphate deaminase 2" Q8TDQ7 4 44682200-44726588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 820000 "Cluster 44: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: AB_2679857" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (3.29e-1)" "unprognostic (1.55e-3)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (9.57e-2)" "unprognostic (9.75e-3)" "unprognostic (1.03e-1)" "unprognostic (1.28e-3)" "unprognostic (4.18e-2)" "unprognostic (6.86e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" 13.1 12.6 9.6 9.8 10.8 8.4 14.5 21.9 13.3 13.9 7.5 12.3 7.9 16.6 14.0 10.1 12.6 10.5 17.5 10.8 9.9 13.8 4.0 10.0 12.6 9.5 9.8 22.6 8.2 13.0 12.8 6.7 9.9 14.7 8.2 18.5 9.2 15.2 11.3 9.7 8.5 16.5 10.4 11.8 9.1 11.6 9.8 13.2 18.1 10.1 10.5 12.0 10.0 12.5 15.7 10.9 11.4 9.7 17.8 24.7 3.9 27.1 30.3 17.9 16.7 5.6 19.1 13.6 15.5 23.4 29.8 5.3 10.6 26.3 19.7 18.4 11.9 19.3 16.6 9.2 18.8 20.8 17.7 28.5 18.1 17.9 13.1 22.6 26.5 18.1 12.2 17.9 33.6 0.7 25.2 11.6 5.5 10.4 19.5 16.3 24.3 8.0 17.3 9.5 19.5 15.8 12.1 7.0 27.2 5.4 14.9 12.1 25.9 23.7 22.6 38.5 31.6 23.0 38.7 19.7 38.6 14.3 21.3 9.3 2.4 5.0 9.7 3.6 11.2 12.2 9.0 9.3 3.7 10.5 11.2 10.8 1.1 9.8 4.9 2.8 10.7 4.7 9.6 10.8 21.9 13.3 10.8 9.9 9.5 9.8 9.9 10.4 9.8 12.5 18.4 9.6 4.6 17.0 19.8 12.5 8.9 18.6 8.0 15.6 9.2 8.1 14.1 2.8 9.4 14.7 8.4 1.2 15.7 3.0 15.6 13.3 30.3 7.9 21.9 14.4 6.7 6.5 29.1 15.1 1.1 22.0 7.1 8.5 15.8 8.5 11.4 1.6 4.8 13.5 29.2 4.4 18.3 3.7 8.7 5.0 16.1 4.2 8.8 8.4 4.3 19.8 13.4 31.2 20.4 14.2 2.9 23.7 6.3 5.2 2.9 13.2 8.0 18.2 13.1 14.3 20.0 34.4 29.9 5.7 10.7 0.5 13.7 20.0 4.4 5.2 GPRASP1 "GASP, GASP1" ENSG00000198932 "G protein-coupled receptor associated sorting protein 1" Q5JY77 X 102651092-102659083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 42.6;Cardiomyocytes: 28.6;Cone photoreceptor cells: 37.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 4.5;REH: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000161, HPA031061" Approved Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA000161: AB_2247872, HPA031061: AB_2673718" "unprognostic (3.92e-3)" "unprognostic (1.10e-1)" "unprognostic (2.07e-4)" "unprognostic (1.42e-1)" "unprognostic (3.32e-2)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (2.33e-2)" "unprognostic (1.58e-1)" "unprognostic (2.82e-1)" "prognostic favorable (1.77e-5)" "unprognostic (3.34e-1)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.23e-2)" 8.6 22.6 25.1 5.4 23.9 3.8 9.9 19.8 31.2 32.4 2.7 23.3 2.4 25.5 10.7 4.4 26.7 7.6 17.7 22.8 33.2 10.3 2.9 7.2 9.4 16.6 17.8 53.4 5.6 17.3 43.5 2.9 18.6 20.4 4.5 29.9 8.7 17.7 6.1 5.2 12.4 15.3 12.8 11.3 9.6 5.3 23.6 6.8 26.1 4.2 7.6 18.6 16.9 20.2 0.2 0.5 1.7 1.1 1.7 1.7 1.0 1.8 0.1 2.7 4.5 0.2 0.3 0.0 0.4 3.8 0.3 0.5 0.5 0.1 3.9 0.0 0.2 0.1 0.6 0.5 1.4 0.2 0.2 2.2 0.7 3.3 0.3 0.4 0.2 1.8 0.3 0.1 4.3 0.4 3.7 0.1 1.2 0.3 0.6 5.6 1.7 0.0 0.2 0.4 1.7 2.7 0.6 0.2 0.5 1.4 0.2 0.9 0.5 0.8 1.0 0.5 0.3 0.3 0.5 0.0 0.4 0.2 1.1 0.0 0.0 0.0 0.5 0.0 1.3 0.2 1.1 0.4 0.0 0.7 2.3 2.3 0.0 0.1 0.0 0.3 0.8 0.5 25.1 23.9 19.8 31.2 22.8 33.2 16.6 17.8 18.6 12.8 23.6 20.2 5.1 0.0 3.6 0.0 4.4 3.6 4.1 0.8 1.8 42.6 1.8 3.0 28.6 1.5 3.5 5.5 37.5 0.4 3.5 0.1 0.0 0.2 0.3 0.6 6.5 7.3 6.0 0.4 0.0 0.2 0.2 9.9 1.1 0.7 2.5 13.9 7.1 0.7 0.3 6.7 0.0 0.7 0.0 0.3 2.0 1.7 15.2 1.3 1.8 0.0 0.5 12.9 3.1 0.0 0.0 0.6 0.1 15.4 2.2 3.8 0.4 1.7 1.2 18.8 6.6 16.9 8.5 7.0 2.4 0.4 0.9 0.1 7.3 6.5 0.8 1.6 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Microglial cells: 56.2;Sertoli cells: 59.2;Smooth muscle cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;HUVEC TERT2: 24.9;OE19: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 38.4 18.0 4.2 5.9 5.0 2.7 24.6 5.0 4.6 18.8 3.5 26.3 10.0 21.1 3.5 12.6 19.6 5.7 48.8 4.0 5.1 14.2 12.9 65.6 7.8 3.9 3.6 35.0 4.7 21.3 13.3 8.3 3.9 14.1 4.9 1.0 7.8 4.0 11.9 11.5 25.8 7.3 3.3 37.0 27.5 4.1 4.9 6.2 19.6 9.7 6.8 19.4 18.1 3.5 3.7 2.3 5.4 5.7 11.8 11.0 1.6 7.1 32.1 4.1 2.3 1.7 5.4 3.9 1.6 11.1 7.5 0.9 2.3 7.7 2.7 15.4 2.0 0.7 4.6 7.0 8.2 0.2 2.0 1.5 1.1 8.5 1.2 5.2 24.9 2.4 0.4 3.7 1.5 0.7 3.8 3.5 0.8 25.8 5.2 1.3 0.8 0.9 0.6 1.5 1.8 4.9 2.4 1.1 7.0 3.0 0.1 0.9 7.8 2.3 1.6 14.6 2.8 0.9 4.4 2.4 4.9 4.4 2.4 0.4 1.5 2.9 2.0 1.4 0.1 3.8 3.0 1.6 0.9 4.0 4.5 2.0 2.1 0.1 0.5 0.0 4.0 1.7 4.2 5.0 5.0 4.6 4.0 5.1 3.9 3.6 3.9 3.3 4.9 3.5 32.6 57.7 3.7 3.6 19.7 1.7 0.7 0.5 1.2 3.9 2.3 2.0 19.4 0.0 1.3 3.7 0.0 3.7 13.3 0.4 0.0 1.1 18.7 0.4 5.1 28.4 4.8 0.0 17.7 3.1 15.8 35.7 18.8 1.0 4.5 7.8 24.7 2.2 4.4 1.7 36.5 0.8 6.1 15.5 6.3 4.9 4.4 14.2 7.2 56.2 3.6 0.0 19.6 14.1 5.7 2.4 1.2 4.5 10.2 0.7 4.9 0.6 0.8 0.9 59.2 18.2 46.5 1.3 2.1 0.7 2.4 13.1 14.1 4.6 0.5 0.9 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Endometrial stromal cells: 45.4;Fibroblasts: 23.0;Late spermatids: 27.1;Oligodendrocytes: 61.3;Skeletal myocytes: 40.0;Theca cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 22.3;JURKAT: 22.1;MOLT-4: 36.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" 6.0 3.8 2.6 5.2 5.3 1.8 4.0 4.3 3.2 5.7 2.6 3.7 0.6 5.6 2.5 3.2 5.1 10.1 13.6 2.0 2.4 0.9 0.3 3.8 1.5 6.2 5.8 16.5 4.2 2.4 1.9 4.0 4.1 3.3 2.0 0.4 5.3 4.0 0.8 1.7 1.2 5.5 5.3 0.7 1.3 5.8 4.6 6.7 8.8 1.5 1.0 5.7 3.6 6.9 0.2 1.8 0.1 11.2 9.9 19.3 1.7 1.8 4.2 4.0 9.8 0.5 1.2 0.0 3.1 4.9 22.3 0.1 1.0 2.2 3.8 0.0 1.3 0.0 7.2 12.4 12.6 4.9 0.0 18.8 1.1 9.7 1.6 6.0 0.0 22.1 5.8 0.1 2.4 2.7 36.5 0.1 6.6 0.1 2.2 0.2 9.5 0.0 1.3 1.7 1.1 5.0 9.8 0.5 1.3 2.0 3.7 1.5 0.1 4.3 13.5 13.3 6.5 1.0 0.1 0.2 11.1 2.3 7.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.3 0.0 2.6 5.3 4.3 3.2 2.0 2.4 6.2 5.8 4.1 5.3 4.6 6.9 1.6 3.2 2.6 7.2 0.1 1.9 1.9 5.3 0.0 0.6 1.5 7.6 14.6 2.8 2.3 0.0 0.0 0.2 1.5 1.4 0.0 0.1 47.9 5.7 45.4 0.6 3.5 0.0 8.3 1.1 0.3 23.0 0.0 7.5 0.0 8.0 0.7 0.0 0.4 0.0 9.0 2.9 0.0 0.0 4.0 27.1 8.1 0.5 0.0 12.2 0.0 2.5 0.0 3.0 61.3 0.8 0.4 7.2 0.0 2.0 0.6 0.5 2.1 0.4 0.0 40.0 3.9 2.5 4.2 0.2 0.4 0.8 0.4 22.9 1.6 0.4 H3Y1 "H3.Y, H3.Y.1" ENSG00000269466 "H3.Y histone 1" P0DPK2 5 17654868-17655849 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "U-2 OS: 1.7" HPA042570 Uncertain NA NA "Cluster 9: U-2 OS - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA042570: AB_2678056" "unprognostic (1.50e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HAS1 HAS ENSG00000105509 "Hyaluronan synthase 1" Q92839 19 51713112-51723991 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.6;ovary: 20.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 26.6;Bipolar cells: 20.3;Cholangiocytes: 38.6;Fibroblasts: 64.2;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "eosinophil: 2.5" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.5" "Cell line enriched" "Detected in some" 4 "U-87 MG: 112.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067602 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA067602: AB_2685871" "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "unprognostic (5.26e-4)" "unprognostic (7.17e-3)" "unprognostic (7.05e-2)" "unprognostic (1.02e-1)" "unprognostic (5.49e-4)" "unprognostic (4.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.43e-2)" "unprognostic (1.72e-1)" "unprognostic (2.30e-11)" "unprognostic (9.12e-4)" "unprognostic (8.99e-2)" "unprognostic (3.73e-4)" "unprognostic (2.43e-2)" 49.6 0.5 1.4 6.3 1.1 3.6 1.3 1.1 1.1 0.1 0.0 2.8 0.1 1.0 0.0 0.8 9.0 5.5 9.2 0.9 2.0 0.5 0.6 3.7 0.0 1.8 0.8 20.8 2.1 0.3 0.9 0.3 0.7 0.2 0.5 0.2 0.2 0.0 0.2 5.4 1.3 0.7 0.3 0.3 1.7 0.3 2.2 0.1 0.7 0.0 0.0 6.3 0.6 1.3 0.0 0.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 3.2 0.0 27.0 0.0 0.1 0.0 0.0 0.0 0.2 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.3 0.8 0.0 0.0 0.0 0.0 112.6 0.0 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 1.1 1.1 1.1 0.9 2.0 1.8 0.8 0.7 0.3 2.2 1.3 1.5 0.0 1.8 0.0 0.2 26.6 0.1 0.8 0.6 20.3 0.0 0.0 1.3 38.6 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 0.5 0.0 0.0 1.7 0.0 0.2 64.2 2.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.8 9.0 0.2 0.3 8.3 8.8 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.5 0.0 3.1 10.6 0.1 0.5 0.4 17.8 0.1 0.3 0.0 0.0 0.2 HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641440 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.7;urinary bladder: 20.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 54.1;Fibroblasts: 62.1;Langerhans cells: 28.9;Melanocytes: 30.2;Smooth muscle cells: 30.7;Urothelial cells: 89.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HBF TERT88: 157.8;hTEC/SVTERT24-B: 153.8;LHCN-M2: 206.5;U-138 MG: 396.9;U-251 MG: 123.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052060 Approved "Nuclear speckles" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA052060: AB_2681712" "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" 22.7 0.3 0.6 9.0 0.5 0.1 5.3 0.6 0.5 0.7 0.1 4.1 2.8 0.8 1.2 1.6 1.7 7.8 4.0 0.5 1.5 1.1 2.9 3.7 1.6 1.6 2.1 0.2 0.9 0.2 0.3 2.3 1.3 1.1 5.6 0.0 1.0 0.2 0.5 2.3 5.2 3.9 1.1 0.1 2.0 1.8 1.3 0.8 0.7 0.9 0.9 20.5 0.6 0.9 0.3 2.8 0.0 0.4 4.7 11.8 0.0 23.5 17.3 29.9 51.2 0.2 0.4 0.1 0.0 20.8 0.0 4.2 0.0 0.0 157.8 0.1 0.6 0.0 0.6 0.0 19.9 0.0 0.0 31.0 0.0 153.8 14.1 0.7 0.0 0.0 0.0 0.0 206.5 0.3 0.0 0.0 0.4 0.0 3.4 0.0 26.6 0.0 0.0 2.0 0.0 0.4 10.0 0.0 5.6 9.0 0.2 0.3 0.0 396.9 1.4 37.7 123.7 0.0 0.0 0.0 8.5 0.1 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.5 0.5 1.5 1.6 2.1 1.3 1.1 1.3 0.9 2.2 0.0 0.0 0.0 0.0 16.3 54.1 1.8 0.6 0.0 0.1 0.4 1.2 0.0 0.2 3.7 0.0 0.2 0.2 1.6 0.0 0.9 19.0 0.1 3.5 7.2 1.2 0.0 0.1 0.0 0.0 62.1 1.1 0.1 13.4 0.0 0.7 0.0 0.3 0.0 0.2 2.3 0.0 0.0 28.9 3.4 1.8 0.7 30.2 0.0 0.0 0.0 0.0 16.1 0.2 1.6 1.9 0.0 0.0 11.0 0.0 0.1 0.0 0.0 0.0 6.9 30.7 0.3 0.1 0.6 11.9 0.1 1.5 0.0 3.9 89.3 HIC1 "ZBTB29, ZNF901" ENSG00000177374 "HIC ZBTB transcriptional repressor 1" Q14526 17 2054154-2063241 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 38.6;Fibroblasts: 44.3;Leydig cells: 57.5;Peritubular cells: 48.2;Sertoli cells: 46.0;Smooth muscle cells: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.9;BJ: 11.9;HSkMC: 7.1;TIME: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043372 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043372: AB_10795614" "unprognostic (1.93e-1)" "unprognostic (9.27e-2)" "unprognostic (6.63e-2)" "unprognostic (4.27e-3)" "unprognostic (2.06e-1)" "unprognostic (1.87e-2)" "unprognostic (3.08e-1)" "unprognostic (6.45e-2)" "unprognostic (8.58e-2)" "unprognostic (2.06e-2)" "unprognostic (1.73e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (9.36e-6)" "unprognostic (2.20e-2)" "unprognostic (3.92e-2)" "unprognostic (1.00e-1)" "unprognostic (5.14e-2)" 24.5 8.6 5.0 5.7 4.0 1.3 16.5 3.4 3.8 23.9 2.8 16.1 6.5 27.0 1.5 5.7 21.5 4.4 23.4 3.0 3.1 12.4 5.9 15.2 2.1 5.7 4.5 30.0 3.8 0.9 19.7 1.4 4.1 20.1 1.7 0.5 5.2 4.5 8.5 5.3 11.7 3.2 3.9 8.9 9.8 4.9 5.6 2.3 12.6 1.2 0.5 17.9 13.9 2.4 0.6 0.7 0.8 0.6 4.7 6.9 1.4 11.9 6.4 1.6 2.3 0.6 0.3 0.1 0.2 6.2 0.6 1.1 0.7 0.2 0.5 0.4 1.5 0.3 0.8 0.3 4.0 0.2 0.5 7.1 0.8 2.4 0.1 3.3 6.2 0.6 1.8 2.8 0.4 0.0 0.1 0.4 0.2 0.0 0.4 0.7 0.3 0.3 0.2 0.4 0.4 0.7 0.2 0.1 0.0 0.2 0.0 0.1 12.4 4.3 0.1 4.2 6.2 0.4 0.4 0.2 0.4 0.4 1.1 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.0 4.0 3.4 3.8 3.0 3.1 5.7 4.5 4.1 3.9 5.6 2.4 25.6 0.0 1.8 1.0 3.9 4.0 2.1 1.5 1.2 2.1 1.9 1.8 5.8 0.0 1.0 1.8 0.0 0.1 19.2 0.1 0.0 0.5 0.5 2.0 38.6 26.9 1.8 0.4 0.2 1.1 0.7 44.3 1.1 1.6 2.5 0.2 23.9 0.3 0.5 0.0 0.3 0.1 2.0 8.5 6.0 1.6 57.5 15.5 3.6 6.5 0.2 0.3 12.3 0.0 0.0 0.2 0.1 48.2 2.3 1.1 0.2 0.1 1.0 1.6 46.0 12.5 30.1 0.8 2.9 1.1 4.1 0.1 13.0 13.3 0.0 2.6 HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265882-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 33.9;intestine: 51.1" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 283.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 7.8;RH-30: 18.0;SCLC-21H: 2.6;SH-SY5Y: 4.1;U-138 MG: 2.9;U-87 MG: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 27000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053903: AB_2682301, HPA070647: AB_2686290" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.69e-1)" "unprognostic (5.53e-4)" "unprognostic (1.05e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-1)" "unprognostic (3.97e-4)" "unprognostic (3.36e-2)" "unprognostic (3.93e-1)" "unprognostic (1.04e-3)" "unprognostic (1.53e-2)" "unprognostic (3.62e-2)" "unprognostic (8.96e-3)" "unprognostic (8.63e-2)" 14.4 1.3 0.3 1.5 0.2 0.0 3.9 0.1 0.7 21.4 0.0 51.1 5.2 33.9 0.1 4.8 10.1 0.7 12.4 0.1 0.9 4.0 1.2 3.8 1.2 2.0 0.7 2.6 0.9 0.1 0.3 0.2 4.0 9.2 1.9 0.0 2.2 2.3 25.0 4.1 21.6 4.2 1.2 0.4 4.9 5.7 1.0 1.2 4.8 6.3 0.2 9.2 12.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.2 0.5 0.0 18.0 0.1 0.0 0.1 2.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.7 0.1 0.9 2.0 0.7 4.0 1.2 1.0 0.4 1.2 3.2 7.5 2.3 0.5 0.9 0.4 0.0 0.0 1.1 0.2 0.3 4.8 0.0 3.7 0.0 0.0 0.1 0.1 22.9 1.9 0.0 17.0 0.0 0.2 5.0 0.0 0.0 1.3 0.0 0.1 24.8 0.0 0.1 7.6 0.1 0.7 2.3 0.4 1.7 5.8 3.6 2.0 0.8 0.8 10.6 0.0 2.3 1.8 1.0 0.0 0.0 0.0 0.5 0.7 0.1 8.3 0.0 0.1 0.8 34.1 1.2 4.0 0.7 0.0 283.7 4.5 0.9 1.1 0.0 0.6 0.3 1.6 2.9 5.5 4.7 HOXA2 HOX1K ENSG00000105996 "Homeobox A2" O43364 7 27100354-27102686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 23.3;Breast myoepithelial cells: 3.8;Enteroendocrine cells: 4.8;Hepatic stellate cells: 6.4;Squamous epithelial cells: 6.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 16 "medulla oblongata: 4.5;pons: 3.3;spinal cord: 4.7;white matter: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.5;HaCaT: 6.2;RPTEC TERT1: 4.9" "Region enriched" "Detected in single" 36 "pons and medulla: 5.8" "Group enriched" "Detected in some" 17 "medulla oblongata: 4.2;pons: 1.1;spinal cord: 3.0" HPA078220 Approved Nucleoplasm,Vesicles Yes NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA078220: AB_2686880" "unprognostic (7.30e-2)" "unprognostic (4.90e-4)" "unprognostic (2.81e-1)" "unprognostic (7.43e-4)" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (1.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.85e-3)" "unprognostic (1.48e-2)" "unprognostic (1.84e-1)" "unprognostic (1.58e-2)" "unprognostic (4.98e-9)" "unprognostic (1.34e-1)" "unprognostic (1.33e-1)" "unprognostic (9.36e-2)" "unprognostic (1.28e-2)" 1.9 1.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 1.6 0.0 3.3 0.9 2.0 5.1 2.3 4.1 1.0 0.2 0.0 0.0 4.4 0.2 1.7 0.2 4.5 0.2 0.6 0.3 5.7 0.0 0.0 3.3 1.7 1.8 0.0 0.0 2.1 0.7 1.6 2.6 0.9 4.7 1.2 2.2 0.1 0.1 1.8 0.8 3.0 0.6 2.0 0.9 4.3 1.1 0.6 4.0 14.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 3.4 0.1 1.5 0.1 1.8 6.2 0.2 0.0 0.0 0.0 2.0 0.0 0.1 0.2 1.8 0.1 0.3 0.8 0.0 3.1 3.1 0.0 2.5 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.9 1.0 0.7 0.0 4.9 0.5 0.9 0.0 0.2 0.0 0.9 0.2 0.0 0.0 2.5 0.0 0.2 1.1 0.5 0.0 0.0 0.1 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 3.3 4.7 0.1 4.3 1.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 23.3 0.0 1.2 3.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.1 1.3 2.5 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 6.4 0.1 0.1 0.0 0.0 1.3 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 1.1 0.5 0.0 0.0 0.0 1.0 1.9 0.0 0.0 6.3 0.3 0.0 0.1 0.0 1.7 0.7 HOXA4 "HOX1, HOX1D" ENSG00000197576 "Homeobox A4" Q00056 7 27128507-27130780 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 11.6;Basal squamous epithelial cells: 31.9;Distal tubular cells: 15.6;Hepatic stellate cells: 16.8;Proximal tubular cells: 13.1;Squamous epithelial cells: 12.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 10 "medulla oblongata: 19.3;pons: 16.1;spinal cord: 15.6;white matter: 14.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.0;HEK 293: 22.2;REH: 21.0;WM-115: 29.1" "Region enriched" "Detected in single" 46 "pons and medulla: 11.3" HPA060088 Approved Supported "Nuclear bodies" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA060088: AB_2684200" "unprognostic (3.37e-2)" "unprognostic (6.27e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (3.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.32e-1)" "unprognostic (4.22e-1)" "unprognostic (1.31e-1)" "unprognostic (7.39e-2)" "unprognostic (4.23e-1)" "unprognostic (5.63e-2)" "unprognostic (2.65e-2)" "unprognostic (3.38e-1)" "unprognostic (3.59e-4)" "unprognostic (3.93e-2)" 16.2 10.0 0.0 2.1 0.0 0.7 10.5 0.1 0.1 5.5 0.0 13.2 4.9 5.9 13.0 15.3 22.1 3.6 1.9 0.0 0.0 16.3 1.5 14.7 1.3 19.3 1.6 6.8 1.9 25.8 0.0 0.1 16.1 5.9 2.4 0.0 0.6 5.8 18.8 4.9 8.2 4.6 15.6 6.9 13.4 1.6 0.0 1.9 3.7 8.2 0.4 7.7 4.6 14.1 9.5 3.1 0.0 29.0 0.0 0.0 1.9 0.9 0.9 3.0 3.0 5.9 1.9 2.5 0.1 2.8 2.7 4.0 1.1 0.4 2.3 0.1 22.2 0.0 0.9 13.7 3.3 3.3 5.4 3.2 2.4 10.2 0.8 0.0 10.3 0.8 0.0 0.0 10.0 2.5 0.0 11.2 0.0 3.3 7.2 21.0 4.4 0.2 14.6 2.2 1.4 0.0 2.9 0.0 11.2 1.0 0.7 1.7 13.5 0.0 4.6 7.6 0.2 0.0 0.0 1.0 6.1 5.1 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 19.3 1.6 16.1 15.6 0.0 14.1 11.6 0.0 0.0 0.0 0.1 0.9 3.1 0.0 31.9 0.0 3.6 7.7 0.4 0.0 0.0 0.0 0.0 0.0 0.4 1.7 15.6 0.0 0.4 0.2 2.6 5.2 3.0 0.8 0.0 0.0 0.9 5.4 0.5 0.1 0.0 0.4 16.8 0.0 0.2 0.0 0.0 0.9 0.0 0.6 0.3 0.4 0.0 0.9 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.7 1.4 0.7 1.0 13.1 0.0 0.0 0.0 8.3 5.8 0.4 3.2 12.5 1.3 0.1 0.8 1.4 2.0 2.5 HOXC5 "HOX3, HOX3D" ENSG00000172789 "Homeobox C5" Q00444 12 54033050-54035361 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;fallopian tube: 4.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.2;Fibroblasts: 2.6;Granulosa cells: 2.5;Leydig cells: 2.5;Peritubular cells: 2.6;Skeletal myocytes: 2.6;Smooth muscle cells: 2.5;Spermatocytes: 3.2;Squamous epithelial cells: 2.2" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.7" "Group enriched" "Detected in many" 15 "medulla oblongata: 3.4;pons: 3.6;spinal cord: 1.9;white matter: 1.2" "Immune cell enhanced" "Detected in single" "gdT-cell: 3.0" "Lineage enriched" "Detected in single" 31 "T-cells: 3.0" "Cell line enhanced" "Detected in some" "AN3-CA: 7.1;ASC TERT1: 4.8;HSkMC: 4.5;SH-SY5Y: 7.6" "Region enriched" "Detected in single" 46 "pons and medulla: 4.6" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.5;spinal cord: 2.1" HPA026794 Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cell Junctions" "HPA026794: AB_10612118" "unprognostic (1.57e-1)" "unprognostic (7.73e-3)" "unprognostic (1.70e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-3)" "unprognostic (2.87e-3)" "unprognostic (6.89e-2)" "unprognostic (9.53e-3)" "unprognostic (1.86e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-3)" "unprognostic (1.17e-2)" "unprognostic (7.53e-3)" "unprognostic (2.19e-3)" "unprognostic (1.08e-2)" 1.0 0.9 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 2.7 0.9 4.1 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.2 3.4 0.1 2.6 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.2 1.2 1.1 0.7 1.5 1.9 0.0 2.1 1.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.2 0.8 1.9 0.0 7.1 4.0 4.8 0.0 0.4 0.3 0.8 0.6 3.0 0.4 0.0 0.5 2.1 0.0 1.1 0.1 0.0 0.3 2.4 2.4 0.0 1.0 0.1 0.1 0.0 0.1 4.5 0.4 3.3 0.4 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.0 1.0 0.0 0.0 7.6 0.5 0.2 3.9 0.9 1.4 0.0 0.0 1.2 0.7 2.6 0.2 0.0 0.0 0.0 0.1 0.1 2.8 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 3.6 1.9 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 5.2 0.0 0.3 0.9 0.1 0.0 0.0 1.8 0.0 0.1 0.8 0.0 1.9 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.6 2.5 3.2 1.0 2.2 0.9 0.3 0.1 1.0 0.1 0.0 HOXC9 "HOX3, HOX3B" ENSG00000180806 "Homeobox C9" P31274 12 53994895-54003337 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 11.0;skeletal muscle: 25.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 41.1;Fibroblasts: 20.1;Granulosa cells: 26.7;Melanocytes: 39.2;Proximal tubular cells: 22.0;Skeletal myocytes: 28.3;Smooth muscle cells: 19.6;Spermatogonia: 21.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.5;HDLM-2: 28.4;HEK 293: 33.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 7.7" "HPA063965, HPA072160" Enhanced Nucleoplasm NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA063965: AB_2685162, HPA072160: AB_2686491" "unprognostic (2.38e-1)" "unprognostic (1.03e-1)" "unprognostic (3.19e-5)" "unprognostic (1.23e-1)" "unprognostic (4.09e-3)" "unprognostic (7.12e-2)" "unprognostic (6.92e-3)" "unprognostic (1.06e-3)" "unprognostic (4.32e-1)" "unprognostic (1.58e-2)" "unprognostic (7.38e-2)" "unprognostic (4.08e-2)" "unprognostic (9.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.01e-1)" "unprognostic (2.74e-2)" "unprognostic (1.53e-1)" 11.0 1.7 0.0 0.3 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.3 0.0 1.0 1.3 0.4 8.1 0.0 0.0 0.0 0.0 9.8 0.0 0.1 1.0 0.0 0.0 2.7 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 25.9 7.8 6.2 0.7 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.5 0.5 0.0 0.8 3.3 0.0 21.5 8.5 7.0 1.5 2.3 2.0 2.8 1.8 0.9 3.3 0.0 1.7 8.8 0.5 3.9 0.5 2.3 2.4 28.4 33.7 0.7 5.9 0.9 0.9 0.1 5.1 7.9 3.6 4.2 1.9 0.0 2.7 0.1 7.1 0.0 5.8 2.5 0.0 2.0 0.0 1.7 0.3 0.4 4.1 0.0 6.5 2.1 0.0 6.2 7.9 4.1 9.5 0.5 6.5 0.3 0.0 5.1 9.0 1.5 2.7 0.0 0.0 0.0 0.1 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 9.6 0.0 0.0 1.8 0.0 6.5 7.9 0.5 0.0 0.0 1.8 0.0 0.3 0.2 0.0 41.1 0.0 3.7 0.1 0.2 2.1 0.0 0.0 0.0 0.4 11.5 20.1 0.0 0.0 0.0 26.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.9 4.1 4.7 0.5 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.9 0.0 0.1 0.6 22.0 0.0 0.0 6.6 28.3 19.6 9.3 21.2 0.7 9.5 0.4 0.5 7.2 0.1 0.0 HRH4 "AXOR35, GPCR105, GPRv53, H4R, HH4R" ENSG00000134489 "Histamine receptor H4" Q9H3N8 18 24460637-24479961 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Early spermatids: 1.2;granulocytes: 1.3;Late spermatids: 1.3;Melanocytes: 1.8;Spermatocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 123 "basophil: 212.9;eosinophil: 61.1" "Lineage enriched" "Detected in many" 191 "granulocytes: 212.9" "Cell line enhanced" "Detected in single" "HL-60: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035009 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA035009: AB_10671507" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (4.68e-2)" "unprognostic (9.83e-6)" "unprognostic (1.31e-2)" "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (8.96e-2)" "unprognostic (2.20e-1)" "unprognostic (3.30e-1)" "unprognostic (7.25e-2)" "unprognostic (2.91e-1)" "unprognostic (6.65e-7)" "unprognostic (1.89e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-4)" "unprognostic (7.70e-2)" 0.1 0.1 0.2 0.4 0.1 0.8 0.0 0.3 0.3 0.1 0.3 0.1 0.5 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.3 0.6 0.5 0.1 0.0 0.3 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.0 1.3 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 212.9 0.1 61.1 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.2 0.5 0.5 0.2 0.1 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.3 0.2 0.0 0.6 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.3 0.4 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.7 1.3 0.0 0.1 1.8 1.0 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.8 0.3 1.3 0.3 0.0 0.6 0.0 0.5 0.2 0.0 0.4 HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 136.5" "Cell type enhanced" "Detected in many" "Ductal cells: 42.5;Hepatocytes: 68.9;Hofbauer cells: 53.9;Proximal enterocytes: 45.3;Proximal tubular cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.8;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.8" "Cell line enhanced" "Detected in many" "HDLM-2: 91.0;Hep G2: 66.2;HMC-1: 98.1;U-2197: 96.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Lipid droplets" "HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379" "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" 27.3 25.7 5.7 10.9 6.2 4.4 17.1 14.7 9.1 8.5 3.5 15.9 19.5 9.5 2.1 12.3 9.4 11.5 11.7 5.9 5.9 27.7 136.5 11.2 8.4 6.3 5.4 8.6 25.6 8.0 5.4 4.5 6.6 8.2 5.8 1.6 10.0 4.5 7.0 18.5 18.4 9.8 5.6 16.3 11.1 6.0 7.1 2.8 6.3 4.5 5.5 13.9 8.7 6.9 20.3 23.2 2.4 11.5 7.9 28.5 1.4 24.8 38.7 4.8 10.0 1.7 34.4 1.2 8.1 30.3 0.8 6.1 2.2 3.6 2.4 91.0 5.4 1.6 18.6 66.2 7.4 0.5 98.1 13.7 6.0 23.1 4.6 11.2 2.2 1.2 4.9 1.0 18.3 43.6 0.6 14.4 1.9 8.5 3.2 2.5 7.8 22.3 15.1 1.3 8.4 4.1 3.2 15.9 2.2 1.1 31.1 1.6 11.5 10.0 2.8 96.1 2.7 1.6 15.4 1.1 39.1 2.5 0.8 61.8 1.4 27.3 0.1 0.1 0.1 0.1 0.1 0.0 1.6 0.2 0.0 0.1 1.2 0.5 0.0 0.6 0.0 0.7 5.7 6.2 14.7 9.1 5.9 5.9 6.3 5.4 6.6 5.6 7.1 6.9 7.6 3.2 4.2 3.3 1.2 7.9 2.6 4.1 4.0 0.7 13.6 9.8 1.7 27.1 2.2 14.7 0.0 2.0 0.5 10.8 15.6 42.5 37.5 1.9 7.1 11.1 7.8 4.8 0.2 30.3 3.5 26.0 8.2 4.2 9.5 9.0 6.8 68.9 53.9 1.7 0.4 11.4 6.1 7.3 15.9 2.2 6.5 11.4 14.2 0.0 12.8 2.1 0.0 0.5 1.2 20.7 14.0 5.3 1.9 1.8 45.3 46.7 1.3 0.5 13.1 9.4 6.3 0.8 1.2 4.9 12.6 1.4 1.7 6.5 23.5 2.8 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 158.8;Leydig cells: 43.5;Peritubular cells: 42.9;Skeletal myocytes: 99.0;Theca cells: 25.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 182.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" 68.0 6.0 0.9 8.7 1.3 13.4 50.4 0.9 1.3 35.4 5.0 33.9 8.7 42.4 10.6 15.1 26.2 35.5 194.9 0.9 1.0 6.2 3.2 38.0 1.2 1.0 1.0 93.0 6.8 0.4 15.7 20.4 1.0 26.3 4.8 0.1 22.8 6.7 32.1 28.1 16.9 11.8 1.0 2.9 21.9 4.3 1.7 2.2 26.0 12.9 0.7 62.4 32.6 0.7 0.0 1.0 1.4 0.0 5.8 10.8 0.3 2.4 0.2 2.8 0.6 0.1 0.1 0.0 13.6 6.4 1.4 0.1 1.2 0.0 0.9 0.0 2.3 1.3 13.9 0.0 6.1 0.0 0.6 1.2 0.0 4.2 0.0 1.7 9.8 0.0 0.3 0.0 10.2 0.0 0.2 36.5 6.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 15.8 0.3 26.4 0.5 0.2 28.8 0.1 1.1 8.1 1.4 4.7 182.1 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.3 0.9 1.3 0.9 1.0 1.0 1.0 1.0 1.0 1.7 0.7 12.6 0.0 0.0 0.0 0.0 5.2 0.5 0.0 0.6 0.0 0.5 0.9 16.5 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 1.2 0.3 8.1 5.3 0.0 0.0 0.0 0.0 4.2 158.8 0.5 0.3 0.0 6.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 8.6 1.4 43.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.4 0.4 0.0 0.1 0.0 0.0 0.0 99.0 10.6 0.4 0.7 0.6 5.3 1.4 0.9 25.2 0.0 0.2 IFFO1 "HOM-TES-103, IFFO" ENSG00000010295 "Intermediate filament family orphan 1" Q0D2I5 12 6538961-6556073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069344 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA069344: AB_2686126" "unprognostic (1.05e-1)" "unprognostic (4.19e-2)" "unprognostic (4.38e-2)" "unprognostic (3.33e-3)" "unprognostic (2.69e-2)" "unprognostic (1.43e-3)" "unprognostic (4.37e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (5.25e-2)" "prognostic favorable (6.53e-5)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.47e-7)" "unprognostic (5.71e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (5.58e-2)" 9.4 7.7 5.4 5.7 5.8 6.3 6.0 6.1 11.5 10.8 3.0 9.1 3.0 10.3 1.5 2.5 8.2 4.4 8.2 6.1 6.3 4.7 5.6 8.0 7.3 6.9 5.1 7.9 3.2 0.6 7.4 4.9 7.2 5.6 2.5 3.6 3.0 5.0 10.6 3.4 6.2 5.3 4.7 11.5 3.7 7.2 6.5 5.0 4.0 4.6 4.8 8.8 6.8 7.6 0.1 0.0 6.1 0.0 9.1 15.0 0.0 9.2 8.3 7.3 6.4 1.2 0.1 1.7 0.0 8.9 2.3 0.0 4.6 1.3 2.4 13.8 15.2 7.2 0.2 10.2 6.3 7.3 11.5 9.2 0.0 5.5 0.0 8.6 7.2 7.7 0.0 2.0 18.2 0.0 6.5 5.8 14.1 0.0 0.0 9.7 10.6 3.3 2.4 0.0 0.0 5.5 0.0 0.0 4.6 6.2 0.0 7.1 11.1 7.0 0.0 5.7 5.2 3.0 0.8 5.6 5.2 3.1 18.7 0.1 4.8 2.8 1.6 3.3 1.5 0.8 1.4 1.7 3.1 0.9 0.5 0.9 1.3 2.7 6.6 1.6 1.1 2.4 5.4 5.8 6.1 11.5 6.1 6.3 6.9 5.1 7.2 4.7 6.5 7.6 14.9 0.0 2.4 16.0 8.9 2.5 0.3 0.7 0.0 15.0 1.3 2.7 10.9 1.5 0.7 0.0 4.2 4.4 17.7 0.6 1.9 0.7 13.2 0.5 9.2 12.6 0.0 3.8 28.9 1.4 3.1 14.1 1.5 0.6 1.3 11.6 11.7 6.5 21.6 21.9 20.5 1.4 0.0 23.1 9.1 11.2 19.0 17.4 19.6 15.9 12.7 11.1 16.5 13.0 10.5 0.4 1.4 13.5 12.0 0.3 1.2 2.8 0.2 12.7 32.9 15.8 13.2 5.6 5.0 0.6 2.0 1.2 12.9 10.1 1.1 0.2 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 580.8;Fibroblasts: 1360.5;Leydig cells: 1030.8;Peritubular cells: 1495.9;Sertoli cells: 1170.1;Smooth muscle cells: 420.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 1163.6;BJ: 476.9;BJ hTERT+: 683.3;fHDF/TERT166: 1045.9;hTERT-RPE1: 468.5;U-87 MG: 631.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 145.8 90.2 28.1 9.2 32.6 0.4 150.5 31.8 40.8 276.6 71.6 75.5 20.8 117.2 129.5 75.8 237.4 36.8 107.0 28.4 33.1 30.6 7.7 40.4 8.7 32.7 29.2 136.8 15.9 4.8 106.3 15.7 33.2 129.3 28.0 6.6 35.9 122.2 38.5 39.2 52.5 39.0 36.7 45.2 67.6 22.2 41.7 6.8 58.4 102.2 9.2 127.1 214.1 27.2 135.3 219.6 0.2 177.3 313.9 1163.6 0.8 476.9 683.3 126.9 69.0 23.2 294.7 0.0 68.5 1045.9 96.4 453.3 3.0 42.3 26.2 1.2 2.8 4.4 37.1 33.3 111.9 0.8 1.1 325.5 2.3 57.4 11.9 468.5 30.5 7.5 0.6 9.3 53.1 0.5 6.6 1.0 6.8 4.1 150.4 2.3 4.9 5.6 10.1 3.3 1.3 8.7 152.2 0.0 10.9 4.0 6.3 0.5 132.2 87.2 41.2 95.5 18.0 5.3 10.7 0.6 631.6 6.7 49.5 0.0 0.0 31.6 0.6 6.8 3.4 0.1 1.0 5.4 2.1 0.0 0.5 6.8 0.0 0.0 20.1 0.0 0.0 1.5 28.1 32.6 31.8 40.8 28.4 33.1 32.7 29.2 33.2 36.7 41.7 27.2 83.9 6.4 4.2 2.0 3.4 113.6 41.0 580.8 23.9 2.5 5.9 29.0 21.1 10.0 37.6 20.2 0.0 3.0 3.5 0.2 11.7 87.9 9.6 4.9 99.2 71.9 0.0 3.2 3.1 8.0 4.9 1360.5 30.5 2.5 0.0 2.3 116.4 0.8 7.6 0.0 3.6 0.3 50.8 6.8 122.8 32.6 1030.8 15.2 144.1 19.7 2.5 51.1 0.0 1.5 0.9 77.1 0.0 1495.9 9.6 94.9 0.0 15.2 13.9 2.8 1170.1 102.3 420.9 3.8 6.8 8.0 87.8 3.4 14.1 0.4 0.0 34.1 IGFN1 "DKFZp434B1231, EEF1A2BP1" ENSG00000163395 "Immunoglobulin like and fibronectin type III domain containing 1" Q86VF2 1 201190824-201228952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skeletal muscle: 186.3" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 103.8" "Cancer enriched" "Detected in some" 4 "thyroid cancer: 8.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "HeLa: 76.6" "Group enriched" "Detected in many" 7 "amygdala: 3.3;basal ganglia: 1.2;cerebral cortex: 2.9;hippocampal formation: 1.9" "Low region specificity" "Detected in some" HPA050415 Enhanced Approved "Midbody ring" Yes NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Midbody ring" "HPA050415: AB_2681120" "unprognostic (2.09e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-2)" "unprognostic (3.25e-1)" "unprognostic (1.02e-2)" "unprognostic (2.00e-2)" "unprognostic (9.80e-3)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (3.80e-2)" "prognostic unfavorable (1.27e-8)" "unprognostic (3.55e-4)" "unprognostic (6.06e-2)" "unprognostic (1.10e-1)" "unprognostic (5.42e-2)" 0.6 0.1 0.3 0.1 0.1 0.0 0.2 0.0 0.3 0.9 0.6 0.1 0.0 10.4 15.1 0.0 0.9 0.2 0.3 1.2 0.6 0.1 0.1 0.5 0.1 0.1 0.2 0.2 7.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.3 186.3 0.3 0.0 0.8 0.0 0.0 0.1 2.5 0.4 0.0 14.6 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 76.6 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 4.9 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 1.2 0.6 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.1 0.0 0.0 0.1 1.5 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 22.1 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 9.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 103.8 0.7 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 IGHV7-4-1 ENSG00000282122 "Immunoglobulin heavy variable 7-4-1" A0A0J9YVY3 14 106025145-106025630 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.4;lymphoid tissue: 133.9" "Cell type enriched" "Detected in some" 4 "Plasma cells: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 109 "memory B-cell: 8.3;naive B-cell: 13.5" "Lineage enriched" "Detected in single" 136 "B-cells: 13.5" "Cell line enriched" "Detected in some" 5 "Karpas-707: 5.4" "Immunoglobulin genes" NA NA 560000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" 3.9 2.9 0.3 58.3 0.0 39.0 21.1 0.0 0.6 7.7 0.2 60.8 8.3 0.5 0.0 4.7 0.8 3.1 0.8 0.0 0.0 2.1 2.8 49.1 7.5 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.0 2.6 97.4 0.0 42.2 8.7 0.3 0.2 42.9 0.2 0.1 68.5 24.2 0.2 0.0 45.6 5.9 0.0 133.9 10.4 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IHO1 "CCDC36, CT74, FLJ25320, LELA1" ENSG00000173421 "Interactor of HORMAD1 1" Q8IYA8 3 49198428-49258106 "Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 7.5;testis: 26.5" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Cardiomyocytes: 1.4;Fibroblasts: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.9;hTEC/SVTERT24-B: 9.2;LHCN-M2: 4.0;NTERA-2: 2.5;U-2197: 5.1;WM-115: 2.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA045690, HPA069534" Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA045690: AB_10964634, HPA069534: AB_2686146" "unprognostic (1.54e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-2)" "unprognostic (1.49e-2)" "unprognostic (9.94e-3)" "unprognostic (2.62e-1)" "unprognostic (1.38e-1)" "unprognostic (1.36e-2)" "unprognostic (5.51e-4)" "unprognostic (3.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.59e-2)" "unprognostic (6.33e-2)" 3.2 1.4 0.2 0.3 0.2 0.2 1.8 0.9 0.5 1.3 7.5 1.1 0.2 1.2 0.4 0.4 1.3 0.7 1.1 0.4 0.0 0.3 0.1 0.5 0.3 0.1 0.3 3.8 0.2 0.1 0.2 0.9 0.1 0.4 0.1 0.7 0.3 0.5 0.9 0.6 0.4 1.0 0.1 0.5 0.3 26.5 0.5 0.1 1.0 0.8 0.1 0.8 0.6 0.1 0.0 0.1 0.0 0.0 1.9 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.1 1.7 0.0 9.2 0.0 0.0 1.2 0.0 0.0 0.1 4.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 5.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.5 0.4 0.0 0.1 0.3 0.1 0.1 0.5 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 39.1;Exocrine glandular cells: 55.2;Fibroblasts: 37.6;Hepatic stellate cells: 36.0;monocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 70.8;EFO-21: 41.3;HDLM-2: 78.5;HHSteC: 42.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 8 "cerebellum: 7.1" CAB026215 Approved "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB026215: " "unprognostic (2.86e-2)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (7.87e-2)" "unprognostic (5.49e-2)" "prognostic unfavorable (2.67e-6)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.18e-3)" "prognostic unfavorable (1.27e-12)" "unprognostic (4.43e-2)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (5.75e-2)" 19.3 7.5 3.3 20.4 3.7 11.7 18.3 3.0 4.6 21.5 3.6 12.3 16.2 15.0 4.6 11.5 18.8 23.2 17.8 2.8 4.4 14.1 19.5 44.5 21.3 5.7 3.9 3.7 11.5 2.2 4.6 16.1 4.6 10.4 10.9 0.3 8.0 5.3 7.1 11.2 15.7 12.1 4.8 15.1 16.3 3.2 4.6 5.7 12.1 10.2 11.6 25.7 12.7 3.5 16.8 2.4 0.0 0.7 21.5 4.9 4.3 8.6 18.4 10.7 11.4 0.3 70.8 1.9 41.3 16.0 6.0 15.6 2.0 12.1 2.4 78.5 3.5 2.0 4.9 1.2 42.7 0.9 0.6 4.1 4.2 6.0 0.2 4.4 29.1 1.3 20.5 23.5 0.3 9.3 3.6 8.9 0.4 6.7 6.8 10.0 0.0 13.4 2.8 1.3 0.1 0.1 12.9 1.4 0.6 0.2 6.1 8.0 10.8 0.5 1.3 30.1 11.2 20.5 6.2 0.4 4.9 12.4 0.7 10.2 26.0 6.6 18.9 32.8 29.1 10.8 14.7 19.7 7.1 6.4 6.1 11.0 7.5 11.5 21.0 0.1 17.7 12.8 3.3 3.7 3.0 4.6 2.8 4.4 5.7 3.9 4.6 4.8 4.6 3.5 25.2 6.4 5.0 1.3 6.0 5.7 5.7 9.9 4.6 0.0 4.4 3.0 5.8 22.8 3.3 0.0 0.0 0.6 4.2 5.8 0.0 39.1 1.7 5.1 23.0 21.0 5.4 19.8 3.3 55.2 1.6 37.6 9.7 6.7 3.8 0.1 36.0 8.7 6.6 0.0 0.9 6.8 2.0 14.7 5.5 2.1 5.0 7.3 3.6 12.2 55.0 0.0 4.1 1.0 0.3 35.5 13.3 0.7 22.2 20.1 9.3 0.1 3.4 0.0 0.0 7.1 6.4 0.2 0.4 4.6 6.5 0.1 7.8 0.0 9.3 6.8 IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 64.0;Early spermatids: 19.3;Excitatory neurons: 17.5;Late spermatids: 35.0;Muller glia cells: 20.2;Oligodendrocyte precursor cells: 20.6" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" 8.4 5.7 71.9 1.6 79.7 0.4 6.4 68.7 58.7 15.2 21.6 5.6 9.4 6.5 1.1 8.9 5.0 5.1 11.6 66.0 70.9 2.6 0.8 6.2 1.2 79.1 62.2 9.3 5.9 0.4 8.9 1.6 61.8 5.5 0.5 10.6 4.3 1.6 131.1 5.4 5.7 1.2 79.6 0.9 4.4 3.9 68.2 0.2 7.6 24.5 0.3 5.4 9.9 79.8 16.5 2.2 3.5 7.6 8.1 4.6 18.3 4.5 1.1 0.4 0.8 7.6 8.7 11.0 0.8 0.4 5.3 8.5 1.5 0.1 0.2 4.0 12.2 0.8 0.7 9.1 1.0 12.2 2.4 6.3 0.1 0.6 0.0 6.9 5.0 15.3 4.5 0.0 3.0 15.9 13.6 10.0 10.7 19.2 2.6 17.8 8.6 1.3 0.2 14.1 20.7 6.7 2.6 3.8 18.3 6.1 9.6 10.4 27.1 1.7 3.0 1.4 5.7 2.0 1.7 2.9 4.0 5.7 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.9 79.7 68.7 58.7 66.0 70.9 79.1 62.2 61.8 79.6 68.2 79.8 0.7 0.0 0.0 64.0 0.2 2.4 0.3 0.0 1.2 1.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 1.1 0.3 0.7 0.0 0.1 19.3 0.2 1.6 0.6 0.0 0.4 17.5 0.2 7.4 7.6 0.0 0.7 0.0 0.9 1.4 0.0 0.4 0.0 12.2 0.1 0.0 0.3 1.9 35.0 11.5 0.2 8.8 2.8 0.0 20.2 0.0 20.6 12.5 0.2 0.1 1.2 0.0 0.5 0.2 0.2 0.0 4.9 0.0 9.4 2.0 8.6 0.6 0.0 2.0 1.1 0.3 0.1 0.3 0.2 IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSG00000144730 "Interleukin 17 receptor D" Q8NFM7 3 57089982-57170306 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 14.0;Early spermatids: 17.9;Late spermatids: 23.7;Microglial cells: 15.0;Peritubular cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 25.0;AN3-CA: 67.9;NTERA-2: 39.2;SH-SY5Y: 102.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039577, HPA043550" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA039577: AB_2676580, HPA043550: AB_2678546" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (2.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-2)" "unprognostic (9.62e-2)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (3.72e-1)" "unprognostic (2.11e-3)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.92e-9)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.63e-3)" "unprognostic (9.58e-3)" 1.9 0.8 4.7 0.9 5.7 0.0 7.4 5.2 4.0 6.0 28.0 5.9 0.4 13.5 10.6 2.4 6.4 3.3 1.9 5.5 6.5 5.7 0.2 0.6 0.3 8.9 8.8 7.4 0.9 9.4 2.3 0.3 5.5 5.1 1.8 0.3 6.0 8.5 0.6 2.0 1.0 12.0 6.2 2.5 1.2 9.7 4.8 0.3 0.5 2.6 0.5 2.8 3.3 6.5 4.0 0.8 25.0 67.9 0.1 0.6 4.0 0.4 0.2 0.3 0.8 0.5 1.9 0.0 0.2 1.4 5.3 0.2 4.8 1.0 0.8 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.1 1.0 2.6 0.0 0.5 16.6 1.1 0.6 0.0 0.1 1.4 0.5 0.0 0.1 39.2 2.2 1.9 0.0 9.1 0.0 5.2 1.0 0.6 102.0 1.0 1.5 2.9 8.1 0.9 0.0 0.7 1.3 1.6 1.2 4.2 0.0 0.0 0.1 0.7 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.7 5.7 5.2 4.0 5.5 6.5 8.9 8.8 5.5 6.2 4.8 6.5 1.4 0.0 2.3 11.4 0.0 0.9 2.0 3.1 0.0 0.1 1.5 14.0 1.6 1.5 2.4 0.0 0.0 0.3 0.1 0.1 0.0 3.1 17.9 0.5 5.5 4.0 0.0 0.0 0.6 0.2 0.1 10.1 0.0 1.0 0.0 2.0 1.1 0.1 0.1 0.0 0.9 0.3 2.0 0.0 1.2 23.7 11.5 0.6 0.0 15.0 0.0 0.6 0.0 7.5 2.1 0.7 0.7 25.9 0.0 2.9 0.0 5.0 1.8 0.0 0.0 4.8 1.3 10.6 7.5 1.1 0.9 0.1 0.3 6.5 0.3 0.7 IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.8;heart muscle: 9.8;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Collecting duct cells: 5.5;Hofbauer cells: 4.7;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HEK 293: 1.9;RPTEC TERT1: 7.1;SK-MEL-30: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" "HPA018332: AB_1851920" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (4.93e-4)" "unprognostic (2.48e-2)" "unprognostic (6.50e-2)" "unprognostic (3.46e-1)" "prognostic favorable (3.34e-4)" "unprognostic (3.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-2)" "unprognostic (2.83e-2)" "unprognostic (9.63e-3)" "unprognostic (7.12e-3)" "unprognostic (5.48e-2)" "unprognostic (5.23e-3)" 9.8 0.1 0.2 0.0 0.6 0.0 4.8 1.1 0.3 2.3 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.1 9.8 0.0 1.1 2.7 0.0 1.8 0.1 0.5 0.8 0.2 0.1 1.7 0.2 0.1 0.6 0.2 0.0 1.6 1.9 0.0 2.8 8.9 0.3 0.1 0.2 1.3 0.0 0.4 0.6 2.2 0.6 1.3 1.1 0.0 0.5 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.1 0.0 1.1 4.8 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.3 0.0 1.1 0.5 0.8 0.6 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.5 0.0 7.5 0.4 0.6 1.3 0.0 1.2 5.5 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.8 0.0 0.6 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.7 5.1 0.0 0.1 3.6 0.0 0.6 1.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.3 0.1 0.5 0.0 1.0 0.1 0.0 0.0 0.0 0.0 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ISM1 "bA149I18.1, C20orf82" ENSG00000101230 "Isthmin 1" B1AKI9 20 13221274-13300651 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 44.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 19.2;Fibroblasts: 18.4;Microglial cells: 8.4;Proximal tubular cells: 5.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 48.9;Hep G2: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 17000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (7.13e-2)" "unprognostic (3.55e-1)" "unprognostic (4.43e-3)" "unprognostic (5.27e-3)" "unprognostic (1.84e-2)" "unprognostic (5.56e-2)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.06e-1)" "unprognostic (4.48e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.32e-6)" "unprognostic (2.58e-2)" "unprognostic (2.10e-1)" "unprognostic (6.83e-2)" "unprognostic (1.81e-2)" 13.2 2.6 1.2 0.3 1.2 0.0 16.6 0.9 1.5 3.3 0.5 2.0 0.4 3.1 0.3 6.6 4.4 4.8 2.9 1.1 3.5 2.1 6.3 4.4 0.3 1.4 1.6 0.5 3.8 0.4 2.1 14.4 1.5 1.6 0.2 0.1 15.2 0.7 1.5 17.0 2.6 1.9 1.3 8.1 3.3 0.1 3.6 4.9 44.4 2.0 0.7 1.3 5.6 0.8 0.0 0.5 0.2 0.7 48.9 6.8 0.3 0.4 4.2 0.0 0.0 2.9 0.4 0.0 0.2 0.0 0.4 0.2 0.0 0.1 0.0 0.0 4.1 0.0 0.0 20.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.4 0.0 0.5 0.5 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.1 4.2 0.0 0.0 1.4 0.2 0.9 0.0 0.0 0.0 2.9 0.4 0.1 0.3 0.0 4.7 0.9 0.0 2.3 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 1.2 0.9 1.5 1.1 3.5 1.4 1.6 1.5 1.3 3.6 0.8 1.9 0.0 0.5 0.0 0.0 4.6 0.4 0.4 0.6 0.8 0.5 19.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.1 0.2 2.0 2.0 0.0 0.0 0.6 0.0 0.3 18.4 0.0 0.2 0.0 3.4 0.0 2.3 0.5 0.0 4.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 1.8 8.4 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.4 0.1 0.5 0.0 5.2 0.0 0.0 0.0 0.4 1.4 0.0 0.3 0.3 2.8 0.7 0.9 0.0 0.0 0.1 ITGA11 HsT18964 ENSG00000137809 "Integrin subunit alpha 11" Q9UKX5 15 68296532-68432163 "Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.3;endometrium 1: 53.1;smooth muscle: 25.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.8;Excitatory neurons: 13.4;Fibroblasts: 30.1;Microglial cells: 18.7;Peritubular cells: 13.5;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 119.5;hTERT-RPE1: 174.5;U-138 MG: 80.6;WM-115: 45.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 7.3;spinal cord: 2.1" HPA051813 Uncertain NA NA 260000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA051813: AB_2681622" "unprognostic (4.85e-2)" "unprognostic (3.51e-1)" "unprognostic (6.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (9.29e-3)" "unprognostic (6.63e-2)" "unprognostic (5.68e-3)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.22e-7)" "unprognostic (8.38e-3)" "unprognostic (2.28e-4)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" 6.5 3.4 0.2 1.1 1.5 0.2 3.2 0.7 1.1 26.3 0.4 2.1 0.8 53.1 13.5 1.5 12.0 2.4 12.7 0.2 0.3 6.5 0.7 1.7 0.5 0.2 0.2 4.6 0.8 0.4 1.8 1.5 0.1 5.2 1.3 0.4 1.2 7.4 2.1 2.7 1.6 25.0 0.1 3.2 1.6 0.9 0.1 0.2 2.0 2.4 0.1 3.9 8.2 0.5 0.0 0.2 0.4 0.9 3.7 0.1 0.1 7.9 15.1 1.6 0.5 0.1 0.2 0.1 0.6 119.5 2.1 0.2 0.0 0.0 0.4 0.0 0.2 0.5 6.8 0.0 10.8 0.2 7.0 1.5 0.0 3.1 0.3 174.5 0.0 0.1 0.2 0.3 20.9 0.1 0.1 0.4 0.7 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.2 0.1 5.5 0.1 0.1 18.5 0.1 0.5 5.0 80.6 0.7 2.1 0.1 0.2 0.0 0.1 13.5 0.2 45.4 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 1.5 0.7 1.1 0.2 0.3 0.2 0.2 0.1 0.1 0.1 0.5 2.9 0.0 0.0 0.3 0.3 0.8 0.5 0.0 0.6 3.9 1.0 7.0 13.8 0.0 0.0 1.8 0.0 0.0 0.3 0.1 1.9 0.3 0.3 0.2 0.8 1.1 0.0 0.0 13.4 0.0 0.1 30.1 1.5 0.3 0.0 0.2 2.2 0.5 0.3 0.0 0.7 0.0 0.0 0.6 1.2 0.5 6.8 0.6 0.0 18.7 0.0 0.3 0.0 0.0 0.5 0.2 0.0 13.5 0.2 0.3 0.1 0.3 0.0 1.6 19.7 2.7 5.4 0.0 0.2 0.2 0.4 0.1 0.6 0.2 0.0 0.3 ITGB1BP1 "ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B" ENSG00000119185 "Integrin subunit beta 1 binding protein 1" O14713 2 9403475-9423528 "Predicted intracellular proteins" "Angiogenesis, Biomineralization, Cell adhesion, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 391.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067348, HPA071538" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA067348: AB_2732765, HPA071538: AB_2686413" "unprognostic (2.21e-1)" "unprognostic (8.31e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.39e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (4.67e-5)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (6.46e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (7.10e-5)" "unprognostic (3.75e-2)" "unprognostic (2.01e-1)" "unprognostic (1.14e-3)" "unprognostic (4.08e-3)" 113.7 23.2 45.5 19.3 63.1 31.3 60.4 50.3 58.0 43.7 49.3 37.3 13.6 31.0 26.6 20.9 24.3 22.6 37.3 46.4 48.3 50.2 13.3 22.8 22.1 48.2 47.0 22.3 11.8 26.2 19.1 24.2 49.9 18.5 24.2 27.5 15.5 23.7 29.8 29.7 19.1 35.9 41.8 15.2 22.9 9.4 54.3 27.0 22.4 33.5 25.7 30.4 32.5 52.7 53.5 35.4 43.4 51.5 148.9 131.2 23.3 94.9 66.2 83.8 66.1 49.5 33.1 55.6 43.1 135.9 56.1 50.1 66.3 62.7 92.8 158.6 30.2 53.2 43.2 61.1 54.1 42.2 57.4 70.5 49.5 78.4 56.5 75.2 76.6 43.0 29.9 46.1 109.0 44.6 74.7 25.5 35.9 90.3 53.9 39.4 59.1 51.4 88.5 40.6 44.1 45.0 54.8 40.3 71.3 38.9 30.5 32.1 48.6 73.8 54.5 103.3 105.7 46.8 111.0 89.0 106.1 54.8 54.5 86.1 43.1 56.0 54.9 54.0 52.5 40.1 46.6 53.2 56.8 33.0 35.2 45.7 9.3 50.4 41.1 52.8 61.7 53.1 45.5 63.1 50.3 58.0 46.4 48.3 48.2 47.0 49.9 41.8 54.3 52.7 90.0 28.9 18.1 18.3 47.1 61.2 40.6 70.4 40.9 25.2 30.4 41.8 104.3 22.8 35.1 38.6 2.1 45.0 70.7 16.1 391.3 72.0 26.3 31.3 51.9 85.5 33.1 49.4 61.6 72.7 73.9 98.6 25.5 30.9 41.7 44.4 53.6 21.6 91.4 35.3 47.3 30.4 32.6 45.0 88.5 25.7 54.3 51.7 97.8 15.9 95.6 64.2 121.5 25.6 40.1 108.9 27.0 57.2 42.7 35.2 24.7 88.4 35.6 30.6 92.1 49.0 102.4 27.8 19.0 47.5 63.1 31.5 63.0 70.7 35.2 60.4 ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 76.1;Skeletal myocytes: 93.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 208.3;ASC TERT1: 138.7;fHDF/TERT166: 345.3;LHCN-M2: 311.8" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 56.9" "Secreted - unknown location" NA NA 37000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.12e-4)" "unprognostic (1.45e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.84e-2)" "unprognostic (2.16e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-5)" "unprognostic (1.44e-2)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.70e-4)" 16.9 9.2 1.8 0.7 1.8 0.1 18.0 2.6 2.3 23.8 2.5 1.5 0.5 2.0 0.5 9.7 4.9 38.3 18.3 1.9 3.6 2.7 7.7 25.4 1.3 3.9 2.3 5.3 7.9 5.6 10.3 33.4 4.3 4.0 2.5 0.1 11.7 4.4 4.5 13.2 0.5 4.1 3.5 4.0 7.2 2.5 2.2 0.9 8.4 14.9 4.3 17.8 10.0 6.5 4.2 0.3 0.0 0.0 208.3 138.7 0.0 65.8 67.7 29.3 18.7 0.0 2.4 0.0 0.3 345.3 13.9 70.9 0.0 24.1 46.0 0.0 0.0 21.3 0.6 0.0 21.7 0.0 0.0 59.3 1.5 16.8 46.6 55.3 76.8 0.0 1.5 0.7 311.8 0.0 0.0 0.0 0.0 0.0 24.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 8.8 24.0 33.2 27.3 0.1 8.3 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 2.6 2.3 1.9 3.6 3.9 2.3 4.3 3.5 2.2 6.5 1.9 3.2 0.5 5.5 0.1 4.0 0.1 1.3 0.6 1.8 4.2 19.0 0.5 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.5 4.5 0.5 7.7 1.2 0.0 0.0 3.6 0.2 0.8 76.1 5.6 1.1 0.0 0.0 8.6 0.5 0.7 5.0 6.7 0.0 0.0 0.0 4.7 2.1 0.0 0.8 5.4 13.1 0.0 0.5 0.0 2.0 5.0 1.1 0.0 8.2 0.6 0.2 0.0 0.1 0.0 0.7 0.0 93.0 4.8 11.6 8.4 0.7 2.4 0.8 0.4 1.2 0.0 0.2 ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 282.7;Fibroblasts: 111.3;Microglial cells: 160.2;Smooth muscle cells: 110.1;Syncytiotrophoblasts: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" 112.7 3.7 17.9 19.4 18.6 0.2 53.3 19.7 23.2 17.4 28.6 62.7 13.9 24.3 6.3 21.4 10.5 27.7 16.8 14.7 18.0 16.4 1.6 22.4 12.5 18.9 18.1 21.2 15.0 6.3 5.4 86.9 19.7 24.0 16.8 3.5 9.5 46.6 17.8 12.0 21.6 28.8 15.7 3.4 24.0 6.2 22.5 3.8 24.5 22.5 13.4 51.4 15.3 15.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 18.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 14.8 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.1 0.0 0.0 0.0 102.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.6 19.7 23.2 14.7 18.0 18.9 18.1 19.7 15.7 22.5 15.2 74.9 3.2 2.7 1.3 0.2 11.3 3.0 0.1 6.8 2.7 1.6 17.3 8.7 8.6 3.7 0.0 2.1 282.7 0.8 0.1 0.0 25.7 2.0 18.7 1.5 58.8 0.0 0.0 0.5 0.4 70.2 111.3 0.0 34.1 2.5 0.5 1.8 0.1 20.7 0.0 0.7 0.0 8.2 1.2 19.6 2.2 5.3 3.6 14.2 160.2 1.1 21.9 0.0 1.5 1.0 0.3 0.0 15.4 0.9 1.8 0.2 2.1 0.7 3.2 78.9 32.3 110.1 1.7 7.7 0.7 8.8 221.9 3.0 0.3 0.0 1.6 JADE1 "JADE-1, PHF17" ENSG00000077684 "Jade family PHD finger 1" Q6IE81 4 128809700-128875224 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020016 Approved Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA020016: AB_1855292" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (1.63e-2)" "unprognostic (3.19e-1)" "unprognostic (2.09e-2)" "unprognostic (7.59e-2)" "unprognostic (6.96e-3)" "unprognostic (6.93e-2)" "unprognostic (8.16e-2)" "unprognostic (9.39e-2)" "unprognostic (8.38e-3)" "prognostic favorable (8.22e-6)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (9.92e-2)" "unprognostic (1.68e-1)" 25.3 21.6 11.7 10.3 12.8 46.2 20.1 21.6 12.4 16.4 10.0 16.3 8.6 12.3 8.7 12.2 18.5 12.6 17.7 10.2 15.9 24.7 11.7 15.9 15.2 13.6 14.1 27.9 70.8 16.5 15.0 11.2 14.8 18.0 6.2 20.4 18.9 17.2 14.9 13.4 12.3 12.7 12.0 15.4 19.1 9.7 15.8 17.8 31.4 11.5 12.3 19.5 12.9 12.1 13.5 25.8 25.2 18.6 33.7 23.7 32.9 21.0 12.5 22.4 20.4 22.8 22.9 40.8 24.3 12.1 9.8 4.5 29.8 7.4 24.9 31.9 13.5 22.8 35.9 20.9 57.9 37.5 17.6 26.5 11.5 27.3 20.2 18.5 24.5 26.1 36.7 54.3 17.5 16.2 47.8 28.0 67.8 13.5 13.1 35.0 17.3 22.0 35.7 6.5 32.7 23.7 20.1 16.2 16.5 35.0 13.1 20.9 17.1 21.9 36.3 16.9 24.8 35.9 32.0 46.0 23.7 36.8 18.3 31.4 10.7 35.9 17.2 17.2 21.1 13.4 18.3 19.2 10.4 18.6 25.5 19.9 13.8 31.1 23.6 4.9 14.6 16.3 11.7 12.8 21.6 12.4 10.2 15.9 13.6 14.1 14.8 12.0 15.8 12.1 24.5 38.5 25.4 17.6 35.4 14.9 16.1 4.3 32.5 40.3 25.8 32.3 33.9 42.9 13.7 49.7 50.1 25.2 42.0 3.1 19.6 30.1 3.6 45.5 21.7 21.7 10.2 48.8 24.5 48.7 16.5 36.7 25.5 37.0 17.7 34.3 18.2 37.3 10.1 28.6 31.8 8.3 46.8 28.5 14.3 4.2 36.1 16.3 21.4 12.2 27.5 26.7 107.1 17.1 19.2 44.0 7.8 48.2 41.2 12.6 12.6 34.7 29.7 28.4 85.5 33.0 59.0 6.6 21.9 20.9 13.4 4.0 40.9 8.9 10.8 5.9 JDP2 JUNDM2 ENSG00000140044 "Jun dimerization protein 2" Q8WYK2 14 75427716-75474111 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Kupffer cells: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 11.8;granulocytes: 7.7;monocytes: 13.2" "Cell line enhanced" "Detected in many" "HHSteC: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059511 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "HPA059511: AB_2684046" "unprognostic (3.19e-2)" "unprognostic (5.58e-2)" "prognostic unfavorable (8.58e-5)" "unprognostic (1.64e-2)" "unprognostic (2.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.99e-2)" "unprognostic (2.81e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (3.25e-2)" "unprognostic (1.86e-1)" "unprognostic (8.11e-3)" "unprognostic (2.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.13e-1)" "unprognostic (9.30e-3)" 53.5 20.0 23.2 29.3 22.0 78.6 40.2 22.8 28.2 31.6 22.0 31.6 22.5 22.7 3.7 25.4 28.5 27.7 39.1 23.5 24.2 18.9 20.5 47.2 13.1 24.6 22.9 21.6 23.1 8.1 17.3 17.5 22.6 21.8 11.3 16.4 24.2 15.0 21.9 29.1 30.1 20.9 22.6 66.8 23.3 4.7 25.4 4.8 25.1 16.7 10.6 25.3 31.6 21.8 15.5 13.5 2.5 26.8 81.5 60.2 90.5 47.5 51.0 30.4 38.1 33.0 13.5 12.4 23.5 90.7 5.6 59.5 16.7 16.2 13.1 16.7 1.9 17.0 26.0 11.9 167.1 24.1 1.3 106.5 95.2 12.4 30.6 11.9 1.5 13.8 2.2 23.0 27.7 76.4 1.4 39.8 9.1 30.4 8.7 8.2 0.3 34.0 14.8 8.6 2.1 10.4 48.9 69.4 55.1 29.7 66.4 52.1 6.2 38.1 57.5 2.4 7.0 18.7 6.0 28.8 11.5 90.0 19.1 0.1 4.5 4.4 0.0 8.1 0.0 11.8 0.2 0.0 2.4 5.1 0.0 0.0 7.7 0.1 13.2 2.1 0.2 1.4 23.2 22.0 22.8 28.2 23.5 24.2 24.6 22.9 22.6 22.6 25.4 21.8 70.7 12.8 33.5 26.8 9.9 16.4 6.0 5.8 19.9 21.8 26.2 18.2 17.7 12.8 8.1 9.2 10.4 1.4 1.2 20.0 0.0 2.4 0.3 21.6 18.4 21.2 5.4 0.8 18.9 6.6 5.6 49.5 10.2 23.9 2.5 10.1 10.4 8.5 9.7 8.4 20.8 14.9 4.1 87.7 25.7 1.5 18.0 47.3 12.4 14.0 13.8 38.6 2.1 18.1 3.0 8.5 8.2 16.6 9.8 2.6 17.7 3.0 7.4 31.1 6.6 47.2 19.5 0.1 0.9 19.7 8.9 0.3 2.2 5.3 8.7 11.5 KCNK15 "dJ781B1.1, K2p15.1, KCNK11, KCNK14, KIAA0237, KT3.3, TASK-5, TASK5" ENSG00000124249 "Potassium two pore domain channel subfamily K member 15" Q9H427 20 44745865-44752313 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Collecting duct cells: 9.2;Exocrine glandular cells: 7.0;Granulosa cells: 6.3;Leydig cells: 6.5;Prostatic glandular cells: 5.6;Urothelial cells: 7.4" "Cancer enriched" "Detected in many" 7 "ovarian cancer: 47.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "MCF7: 48.9" "Region enriched" "Detected in single" 18 "olfactory bulb: 6.8" "Region enriched" "Detected in single" 7 "olfactory bulb: 3.9" HPA064861 Uncertain NA NA "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 50: Fibroblasts - ECM organization" "HPA064861: AB_2685373" "unprognostic (8.70e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.05e-2)" "unprognostic (2.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.50e-2)" "unprognostic (4.22e-2)" "unprognostic (2.64e-2)" "unprognostic (1.19e-1)" "unprognostic (4.60e-2)" "unprognostic (6.27e-2)" "unprognostic (6.11e-2)" "unprognostic (7.38e-4)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (2.21e-3)" "unprognostic (2.11e-1)" 4.0 2.1 0.3 0.2 0.5 0.0 3.0 0.1 0.4 3.2 0.2 0.5 0.2 2.3 0.2 0.7 5.2 1.0 1.7 0.1 0.9 2.0 0.3 2.0 0.0 0.2 0.3 2.2 1.6 0.1 3.5 0.1 0.1 1.6 0.0 0.2 1.7 1.3 0.4 1.4 0.6 1.1 0.1 0.1 2.8 3.3 0.2 0.0 2.7 0.2 0.0 1.0 1.5 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.4 0.3 0.1 0.1 0.3 0.0 0.0 0.8 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 48.9 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.4 0.0 1.4 0.6 4.6 0.0 0.5 0.0 2.3 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.4 0.1 0.9 0.2 0.3 0.1 0.1 0.2 0.0 1.0 0.0 0.0 0.0 0.1 0.5 1.9 0.0 0.6 0.1 1.6 1.0 0.7 15.7 0.4 9.2 0.0 0.0 0.0 0.3 0.0 3.9 0.2 1.7 2.3 2.5 1.2 0.0 1.0 7.0 0.0 3.9 1.1 1.6 0.0 6.3 1.4 0.3 0.1 0.0 0.5 0.4 0.0 0.0 0.3 0.3 6.5 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 1.5 0.3 0.4 0.0 5.6 0.0 0.2 0.1 0.1 0.0 0.5 0.6 0.2 0.4 1.4 0.9 0.0 0.1 0.3 1.0 7.4 KCNN1 "hSK1, KCa2.1" ENSG00000105642 "Potassium calcium-activated channel subfamily N member 1" Q92952 19 17951293-18000080 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "brain: 92.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 12.8;Langerhans cells: 19.8;Skeletal myocytes: 6.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.5" "Group enriched" "Detected in many" 7 "amygdala: 34.8;basal ganglia: 30.6;cerebral cortex: 67.2;hippocampal formation: 92.2;white matter: 30.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "REH: 155.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065938 Approved "Actin filaments,Cytosol" Yes No "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments, Cytosol" "HPA065938: AB_2685582" "unprognostic (7.55e-2)" "unprognostic (4.03e-2)" "unprognostic (1.82e-1)" "unprognostic (7.80e-2)" "unprognostic (1.90e-1)" "unprognostic (8.94e-5)" "unprognostic (3.92e-3)" "unprognostic (1.01e-1)" "unprognostic (8.42e-2)" "unprognostic (3.59e-1)" "unprognostic (2.71e-3)" "unprognostic (3.38e-1)" "unprognostic (5.21e-3)" "unprognostic (2.70e-2)" "unprognostic (1.14e-1)" "unprognostic (7.24e-3)" "unprognostic (3.24e-1)" 0.3 0.2 34.8 0.4 30.6 0.1 0.2 0.0 67.2 0.9 0.0 0.3 0.1 0.6 0.1 0.2 0.1 0.1 1.1 92.2 0.0 0.2 0.0 0.1 0.1 4.4 0.0 1.8 0.1 1.6 1.0 0.0 6.8 0.6 0.0 0.8 0.4 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 2.2 0.0 0.1 0.1 0.0 0.1 0.1 0.2 30.6 0.1 0.6 0.2 6.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.5 0.2 5.3 0.0 0.2 0.2 2.5 5.0 0.3 0.1 0.0 0.0 12.8 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.4 0.0 0.0 1.8 0.0 0.1 155.3 0.0 0.2 0.0 0.0 0.2 8.6 0.0 0.0 0.1 0.4 0.3 0.2 0.1 0.0 4.7 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 30.6 0.0 67.2 92.2 0.0 4.4 0.0 6.8 0.0 0.0 30.6 0.4 0.0 0.0 3.6 1.1 2.5 3.7 0.0 0.0 2.3 0.2 0.3 0.8 0.0 0.7 0.0 2.1 0.1 1.5 0.2 0.0 0.0 0.2 1.3 1.5 1.9 0.0 0.0 12.8 0.0 0.2 2.6 0.0 1.9 0.0 3.6 0.4 0.2 0.1 0.0 4.4 0.0 0.0 0.3 19.8 0.4 0.9 2.1 5.4 1.9 2.2 1.4 1.0 3.0 0.7 0.2 0.0 1.9 0.7 2.8 0.0 0.2 0.0 1.0 0.0 6.8 1.8 0.6 4.0 0.0 3.8 0.1 1.5 2.2 0.0 1.8 KERA "CNA2, SLRR2B" ENSG00000139330 Keratocan O60938 12 91050491-91058024 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Fibroblasts: 2.0" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "amygdala: 4.1;basal ganglia: 5.6;cerebral cortex: 6.2;hippocampal formation: 5.6" HPA039321 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 50: Fibroblasts - ECM organization" "HPA039321: AB_10795248" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (4.76e-3)" "unprognostic (3.65e-1)" "unprognostic (6.08e-2)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-3)" "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 KLF2 LKLF ENSG00000127528 "Kruppel like factor 2" Q9Y5W3 19 16324826-16328685 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 1043.3;B-cells: 691.8;dendritic cells: 542.9;Endothelial cells: 511.8;Gastric mucus-secreting cells: 561.7;NK-cells: 466.5;Plasma cells: 806.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 26.8;TIME: 67.8;U-266/70: 45.6;U-266/84: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055964 Approved Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA055964: AB_2682989" "unprognostic (3.22e-3)" "unprognostic (1.89e-2)" "unprognostic (3.13e-2)" "unprognostic (1.72e-3)" "unprognostic (1.04e-1)" "unprognostic (7.91e-3)" "prognostic favorable (8.55e-4)" "unprognostic (1.74e-1)" "unprognostic (3.09e-2)" "unprognostic (4.28e-2)" "unprognostic (4.90e-1)" "unprognostic (1.52e-1)" "unprognostic (9.76e-3)" "unprognostic (7.80e-2)" "unprognostic (1.76e-1)" "unprognostic (3.50e-1)" "unprognostic (7.56e-2)" 153.7 27.1 25.0 61.6 23.2 90.0 108.4 15.4 18.5 59.2 10.9 55.2 9.6 61.5 2.5 32.2 105.9 14.7 118.4 13.6 17.9 41.6 13.4 110.8 45.4 27.3 34.1 152.6 12.5 5.6 28.8 22.4 24.2 41.8 5.0 0.6 35.7 6.8 52.0 65.5 44.6 19.5 14.1 70.9 73.1 18.3 27.9 13.0 53.5 20.5 8.3 86.9 63.8 15.5 7.5 1.8 0.1 1.6 0.4 1.0 2.9 16.6 1.8 5.5 1.8 0.1 24.0 0.7 3.7 6.7 0.9 2.5 0.5 0.0 1.5 0.6 2.0 0.0 1.4 0.2 4.2 0.0 12.1 1.2 0.2 1.4 0.3 7.1 10.9 14.7 0.5 15.4 2.4 0.4 1.5 3.2 0.2 7.3 2.2 0.5 4.3 26.8 0.2 0.3 0.5 0.2 0.9 12.3 10.4 0.1 0.5 8.6 67.8 12.9 9.4 1.0 23.8 45.6 49.3 1.6 5.7 0.0 5.8 63.2 8.3 25.1 42.7 32.9 34.9 44.7 56.6 43.9 3.3 47.5 53.5 44.4 79.5 28.7 29.1 0.6 59.4 20.5 25.0 23.2 15.4 18.5 13.6 17.9 27.3 34.1 24.2 14.1 27.9 15.5 1043.3 35.3 60.0 1.0 691.8 23.8 25.9 7.4 30.1 5.8 69.6 51.8 47.9 31.5 9.0 3.7 8.4 4.5 542.9 151.7 0.0 10.3 2.3 53.8 31.1 511.8 46.4 35.0 0.8 6.0 7.6 350.6 561.7 20.4 33.6 8.1 393.3 10.6 91.3 0.0 1.9 110.5 2.0 242.4 58.5 6.3 89.5 272.9 64.0 48.7 74.1 7.6 466.5 0.5 0.3 64.3 61.3 73.0 806.5 10.7 4.8 1.9 18.2 8.8 65.7 460.9 235.3 0.8 2.9 22.1 26.3 6.6 417.8 57.9 33.7 12.9 KLF9 BTEB1 ENSG00000119138 "Kruppel like factor 9" Q13886 9 70384597-70414624 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 264.3;Skeletal myocytes: 223.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.4;ASC TERT1: 83.0;HHSteC: 107.4;HSkMC: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029308 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane, Cytosol" "HPA029308: AB_10601923" "unprognostic (2.12e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (2.69e-2)" "unprognostic (5.86e-2)" "unprognostic (1.37e-1)" "unprognostic (3.64e-3)" "unprognostic (4.34e-1)" "unprognostic (5.55e-1)" "unprognostic (9.47e-2)" "unprognostic (7.86e-2)" "unprognostic (3.44e-1)" "prognostic favorable (6.59e-6)" "unprognostic (1.43e-3)" "unprognostic (1.75e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" 82.0 36.5 12.5 22.8 22.1 18.2 67.6 29.8 22.5 29.9 14.9 66.5 15.3 56.5 16.7 41.1 73.0 42.6 54.7 15.7 14.4 54.9 91.3 71.6 14.4 21.3 21.1 63.4 52.9 51.1 25.5 10.2 17.3 36.5 26.2 19.2 35.4 24.4 123.3 40.8 33.2 58.9 15.6 22.9 48.9 7.7 21.7 12.1 57.1 94.7 14.3 43.4 37.2 19.1 0.4 0.6 0.0 7.8 60.4 83.0 0.8 4.1 27.1 1.4 3.0 0.1 3.6 0.1 3.0 7.5 2.0 0.1 11.9 18.4 2.8 0.0 9.3 4.2 13.1 2.4 107.4 2.1 10.9 71.6 18.4 1.1 25.9 37.1 23.9 1.8 8.4 16.4 10.2 1.3 0.3 6.2 0.7 1.2 3.9 0.0 3.7 10.9 5.0 0.0 1.0 5.2 37.3 21.5 45.2 2.5 7.1 6.7 32.8 7.1 5.1 8.2 2.2 11.8 13.5 0.6 6.4 6.6 35.9 0.7 0.1 0.1 0.4 0.1 0.6 0.9 0.5 0.4 0.3 0.6 0.7 0.4 0.0 0.1 0.2 0.4 0.6 0.1 12.5 22.1 29.8 22.5 15.7 14.4 21.3 21.1 17.3 15.6 21.7 19.1 264.3 41.7 25.5 25.8 36.5 48.2 62.7 13.0 97.3 45.3 48.3 34.7 74.1 64.3 22.3 14.7 20.9 0.2 51.0 36.7 31.3 10.5 22.3 40.6 171.6 124.3 13.8 14.5 32.1 13.1 0.5 180.8 55.5 59.6 7.6 2.0 109.9 158.8 3.7 80.8 13.7 32.3 14.2 70.1 44.6 18.1 90.7 81.3 39.2 29.0 9.7 126.1 19.6 3.0 11.1 12.8 26.1 85.0 30.2 74.0 54.5 39.7 17.4 10.1 78.9 223.8 203.5 2.1 3.2 72.7 34.2 0.0 54.9 16.3 31.9 33.3 KLHL26 ENSG00000167487 "Kelch like family member 26" Q53HC5 19 18637025-18671721 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023074 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA023074: AB_2671060" "prognostic favorable (5.01e-4)" "unprognostic (1.50e-3)" "unprognostic (2.54e-2)" "unprognostic (2.26e-3)" "unprognostic (1.23e-2)" "unprognostic (2.70e-3)" "unprognostic (1.62e-2)" "unprognostic (5.32e-3)" "unprognostic (9.12e-2)" "unprognostic (1.77e-2)" "unprognostic (9.04e-3)" "unprognostic (9.76e-2)" "prognostic favorable (1.25e-6)" "unprognostic (1.82e-2)" "unprognostic (2.76e-1)" "unprognostic (3.92e-2)" "unprognostic (4.49e-2)" 7.2 4.5 9.2 2.6 10.2 3.1 6.0 7.4 11.9 6.0 1.7 5.8 1.9 5.5 2.2 3.6 6.6 1.7 7.0 9.6 6.9 4.2 3.7 4.5 2.4 7.4 7.0 6.6 5.2 2.6 6.3 1.4 5.2 5.7 1.3 1.6 4.1 3.3 8.1 5.8 4.0 1.5 6.4 3.9 5.7 4.4 7.9 1.9 7.2 3.3 1.1 5.2 4.8 7.9 6.0 2.6 2.2 3.7 5.0 2.2 8.0 2.2 0.6 2.5 1.6 3.6 4.9 4.3 7.5 1.8 1.9 4.5 2.9 1.4 1.1 3.1 7.6 2.2 4.5 3.3 6.4 3.2 3.6 2.2 2.5 1.3 0.9 2.4 1.5 5.0 5.0 4.9 0.9 5.7 7.8 4.8 3.8 3.4 9.0 7.2 0.2 4.5 2.5 2.9 2.4 5.0 5.5 4.0 2.8 1.3 3.6 6.4 4.7 1.2 1.1 0.2 4.2 7.4 4.6 6.5 4.4 5.6 1.7 0.6 1.5 0.8 1.5 0.9 2.4 1.3 1.5 1.8 1.3 1.5 1.5 1.5 1.1 4.4 0.9 1.2 0.6 1.3 9.2 10.2 7.4 11.9 9.6 6.9 7.4 7.0 5.2 6.4 7.9 7.9 2.3 3.2 1.1 7.8 1.9 1.0 1.7 2.1 7.4 4.4 4.2 3.6 3.3 5.7 1.1 0.0 4.2 3.1 2.2 2.4 13.7 3.9 0.8 2.1 2.2 2.2 6.7 2.7 3.3 2.3 1.4 4.7 3.6 2.9 11.4 3.1 2.9 4.0 4.0 6.7 2.1 3.3 6.1 3.5 2.2 0.7 3.1 2.5 1.8 3.7 4.9 11.6 1.0 1.0 3.0 2.8 2.1 2.2 0.7 1.6 1.8 3.4 1.2 2.3 6.6 8.9 4.9 3.2 6.5 3.3 1.8 1.9 3.7 1.7 3.6 1.0 KREMEN1 "KREMEN, KRM1" ENSG00000183762 "Kringle containing transmembrane protein 1" Q96MU8 22 29073035-29168333 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 59.1;Skeletal myocytes: 82.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;neutrophil: 4.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "RH-30: 34.7;U-2197: 59.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058513 Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No 1100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA058513: AB_2683739" 7.3 13.5 10.3 9.5 22.3 4.1 7.6 7.4 10.8 9.1 5.6 13.1 6.6 6.7 8.7 37.2 10.9 4.0 22.7 12.7 7.6 9.0 2.4 11.9 2.9 8.2 9.8 22.2 4.6 48.2 6.5 6.1 8.0 9.1 11.3 4.0 28.3 9.8 28.7 36.3 11.1 6.2 5.6 9.1 9.4 12.5 12.9 22.4 9.5 42.6 16.4 9.2 13.7 8.3 5.2 3.6 11.8 6.2 3.9 11.9 9.9 1.4 12.0 3.8 5.7 16.5 2.4 0.1 4.5 5.6 9.6 24.7 24.6 9.9 4.1 6.2 15.5 1.4 1.7 15.6 4.1 0.1 1.3 11.4 19.7 4.3 2.4 1.6 0.6 10.1 5.4 0.3 4.8 4.4 0.1 1.7 0.5 34.0 2.5 0.8 34.7 0.3 4.1 9.7 23.6 13.1 14.2 5.0 18.3 3.9 18.5 0.9 0.4 15.7 4.8 59.3 1.7 1.2 0.4 0.2 10.0 2.2 18.5 1.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 4.6 0.3 0.2 0.6 0.1 0.1 10.3 22.3 7.4 10.8 12.7 7.6 8.2 9.8 8.0 5.6 12.9 8.3 2.0 16.0 18.4 59.1 0.3 15.3 14.0 14.1 7.4 4.4 5.7 6.1 23.9 14.3 18.3 7.3 0.0 15.5 0.3 3.9 1.9 5.4 3.2 6.2 19.7 3.9 0.0 17.2 10.3 4.2 1.8 24.4 8.6 8.0 19.0 5.9 5.3 2.6 2.6 0.0 2.7 19.4 4.1 24.1 6.8 10.8 17.7 2.5 0.0 15.9 2.7 22.2 2.1 10.6 6.3 3.0 9.5 10.5 0.1 10.9 2.2 4.7 18.4 3.4 13.1 82.2 7.9 8.1 6.0 26.3 19.5 5.3 2.3 33.5 10.2 10.5 KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 178.0;lymphoid tissue: 76.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Fibroblasts: 4.6;Leydig cells: 3.1;Syncytiotrophoblasts: 4.0" "Group enriched" "Detected in some" 4 "cervical cancer: 9.6;head and neck cancer: 15.0;urothelial cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "SK-BR-3: 7.0" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in some" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA 300000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments, Cytosol" "HPA022978: AB_1852230" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (3.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "unprognostic (3.37e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 8.0 0.0 0.1 16.7 178.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 5.8 0.2 2.2 1.6 0.0 0.0 0.3 0.5 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 76.3 2.6 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.2 4.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 4.0 0.0 0.0 0.0 0.0 KRTAP13-4 KAP13.4 ENSG00000186971 "Keratin associated protein 13-4" Q3LI77 21 30430230-30431026 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 60000 "Cluster 50: Fibroblasts - ECM organization" 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LAMA2 LAMM ENSG00000196569 "Laminin subunit alpha 2" P24043 6 128883138-129516566 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 106.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 363.1;Fibroblasts: 151.1;Leydig cells: 184.2;Microglial cells: 692.3;Oligodendrocytes: 160.9;Peritubular cells: 224.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 255.1;ASC TERT1: 184.5;HHSteC: 55.5;HSkMC: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB040310, CAB078182" Enhanced "Secreted to extracellular matrix" NA NA 55000000 "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB040310: , CAB078182: AB_2665829" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (2.17e-2)" "unprognostic (3.17e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (9.73e-2)" "unprognostic (3.67e-2)" "unprognostic (2.44e-3)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (4.04e-2)" "unprognostic (1.24e-3)" "unprognostic (6.16e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (3.65e-5)" 37.6 9.2 2.7 2.6 10.2 0.0 25.0 4.1 5.8 24.1 10.8 14.8 1.7 17.1 4.1 8.0 34.9 18.0 64.0 1.8 3.4 4.1 4.4 26.5 1.0 13.8 4.6 53.4 8.0 2.8 6.9 106.0 8.3 7.3 4.7 2.5 14.9 9.0 22.0 14.1 13.7 14.2 4.7 5.0 17.4 9.2 7.5 2.7 14.6 42.9 0.7 18.1 18.1 6.4 0.0 0.1 2.8 0.1 255.1 184.5 0.0 26.1 9.5 0.6 0.6 0.0 0.2 0.0 0.3 28.2 0.2 0.1 1.6 0.1 0.6 0.1 0.0 0.1 0.0 0.0 55.5 0.0 0.3 156.4 0.1 13.5 0.3 0.2 0.3 0.0 0.0 1.0 44.1 0.0 0.0 0.1 0.5 0.8 0.0 0.0 14.5 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 22.2 1.4 0.1 0.3 8.9 0.3 0.0 1.7 0.0 2.9 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 2.7 10.2 4.1 5.8 1.8 3.4 13.8 4.6 8.3 4.7 7.5 6.4 7.7 0.0 0.5 24.8 0.0 3.7 2.2 0.5 1.2 1.3 1.1 0.8 90.7 0.0 0.9 0.0 0.0 2.1 0.5 0.0 0.0 1.4 7.5 6.5 75.1 8.5 0.0 0.0 363.1 0.2 1.9 151.1 11.7 6.5 0.0 1.0 3.6 0.0 3.0 0.0 8.6 0.0 0.0 0.0 4.4 11.7 184.2 1.9 1.8 692.3 0.1 11.1 3.1 8.0 160.9 0.9 0.0 224.2 0.5 1.0 0.0 0.6 4.5 1.1 118.3 122.1 8.8 2.6 1.9 1.2 2.8 3.8 1.7 44.5 0.0 1.1 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.8;Leydig cells: 146.3;Peritubular cells: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 299.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 25000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" 75.2 73.2 12.8 18.2 14.2 2.6 58.2 15.1 14.9 68.0 47.7 63.1 24.6 72.7 25.5 31.9 63.8 62.2 169.1 13.1 14.5 41.3 31.7 55.1 16.9 20.0 14.8 94.4 32.7 104.7 15.4 99.0 15.4 50.4 18.0 11.7 40.3 81.0 67.5 40.9 32.5 80.2 14.1 29.8 48.4 21.4 17.3 6.7 60.2 70.0 12.8 52.2 55.9 13.5 15.7 38.7 34.4 122.0 196.3 201.5 31.1 131.9 161.8 73.8 75.7 18.3 52.0 0.2 44.4 299.0 38.3 49.3 30.0 47.6 52.3 0.1 9.5 6.9 63.4 32.1 132.5 0.3 0.3 176.9 69.4 61.6 62.1 184.3 75.9 0.0 4.1 0.1 61.4 30.3 0.1 0.3 15.1 20.7 32.0 0.2 16.6 0.5 53.5 19.1 0.2 20.4 74.9 42.9 68.3 57.5 93.4 0.9 126.9 82.2 34.9 28.5 35.4 0.1 0.4 0.4 39.1 0.3 57.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 14.2 15.1 14.9 13.1 14.5 20.0 14.8 15.4 14.1 17.3 13.5 83.7 118.6 53.5 26.1 2.4 31.2 13.9 33.6 33.0 1.7 39.4 40.5 151.8 37.1 43.6 55.2 6.2 11.3 0.9 3.6 5.9 26.4 3.5 15.4 24.4 77.8 0.0 0.4 0.2 9.4 6.4 120.1 50.4 27.2 1.3 88.9 94.9 49.9 10.4 8.4 0.4 3.1 32.6 10.1 31.1 12.3 146.3 7.5 42.7 15.9 3.5 46.7 2.1 1.0 0.6 14.1 14.9 140.7 0.5 10.2 16.4 28.6 11.2 2.6 118.3 80.8 92.3 4.3 8.6 14.2 24.4 9.4 3.8 27.6 5.6 9.3 LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 231.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1582.4;ASC TERT1: 863.5;HSkMC: 980.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" NA NA 100000000 "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Plasma membrane" "CAB004486: AB_627870, CAB078163: AB_2665817, HPA001908: AB_1079229, HPA001909: AB_1079230" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-2)" "unprognostic (8.84e-3)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.38e-2)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-3)" "unprognostic (1.10e-3)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.85e-5)" 117.2 16.4 6.3 34.9 7.2 1.1 79.3 9.2 7.1 55.1 13.8 78.3 16.0 63.2 19.3 44.5 63.8 54.7 61.7 7.2 8.7 19.4 13.8 58.7 15.3 6.9 7.7 36.1 19.2 20.0 9.5 231.7 6.0 31.3 34.3 3.7 28.1 50.9 50.5 40.8 48.9 102.3 6.4 8.4 51.1 18.7 8.6 14.7 40.3 60.1 12.0 66.9 47.7 5.4 52.5 83.5 268.4 76.7 1582.4 863.5 405.0 374.8 373.0 147.8 87.1 249.4 58.2 18.8 168.6 180.8 87.9 127.4 51.7 99.2 112.7 0.6 52.6 0.9 71.1 91.3 248.1 16.6 8.9 980.4 52.2 177.0 138.7 262.7 261.0 0.2 0.6 55.5 182.5 22.8 0.2 17.4 109.3 96.0 15.7 13.5 226.2 9.9 237.6 137.0 17.6 50.1 98.9 0.7 95.6 459.0 21.2 43.6 486.5 179.1 70.0 168.2 95.4 21.6 0.3 12.4 148.7 12.3 177.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 7.2 9.2 7.1 7.2 8.7 6.9 7.7 6.0 6.4 8.6 5.4 81.2 35.3 21.6 32.7 8.1 31.4 46.1 44.4 35.9 3.1 7.1 17.4 57.5 27.1 21.0 36.8 4.2 101.9 0.2 1.6 1.9 59.2 5.7 32.5 58.5 80.9 1.2 0.0 69.2 23.3 69.0 187.8 8.6 78.5 2.5 53.0 26.7 19.1 18.7 1.7 50.0 2.4 18.3 10.7 20.6 6.8 120.9 4.5 33.8 106.8 6.0 2.2 1.0 35.2 2.5 44.7 2.6 62.4 11.0 59.9 0.5 12.4 14.8 0.7 72.3 73.9 102.1 17.6 36.8 17.0 16.9 72.1 2.8 74.4 3.5 25.8 LARP6 "acheron, FLJ11196" ENSG00000166173 "La ribonucleoprotein 6, translational regulator" Q9BRS8 15 70829130-70854157 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 429.0;Late spermatids: 259.8;Spermatocytes: 166.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 232.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020338, HPA049029" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Microtubules "Cytokinetic bridge" "HPA020338: AB_1844500, HPA049029: AB_2680604" "unprognostic (1.35e-3)" "unprognostic (1.95e-1)" "unprognostic (7.43e-2)" "unprognostic (2.63e-3)" "unprognostic (2.96e-2)" "unprognostic (4.70e-2)" "unprognostic (2.44e-2)" "unprognostic (2.80e-3)" "unprognostic (4.27e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (9.90e-5)" "unprognostic (4.51e-3)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" "unprognostic (3.43e-1)" 51.4 9.8 42.8 6.5 69.8 0.1 44.0 56.9 65.5 27.5 22.8 18.5 2.1 22.8 28.4 7.9 29.0 10.9 43.4 44.5 52.0 27.9 10.6 17.9 2.3 57.8 56.6 30.4 10.9 19.6 23.6 7.7 56.4 26.1 4.0 11.8 19.5 14.1 17.6 14.0 10.3 12.1 46.8 2.6 26.9 9.6 55.9 5.1 40.8 26.1 1.5 21.1 31.0 90.4 42.3 44.2 14.1 28.3 70.2 77.9 0.1 127.7 99.0 67.4 71.2 12.9 12.0 0.0 50.9 69.9 65.4 22.7 32.0 11.2 66.4 0.4 78.3 0.2 37.6 12.0 127.1 0.2 0.2 49.0 45.6 67.9 107.5 70.6 22.2 15.4 0.1 0.6 30.4 7.3 0.3 0.3 14.9 0.0 113.9 0.2 50.6 0.3 22.0 35.9 8.4 18.5 42.5 0.5 93.1 21.7 2.3 2.4 29.6 27.4 109.6 232.0 107.5 0.2 0.3 0.4 116.9 0.0 14.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 42.8 69.8 56.9 65.5 44.5 52.0 57.8 56.6 56.4 46.8 55.9 90.4 32.3 0.0 1.1 2.9 0.1 18.1 47.7 20.4 9.6 41.4 15.4 18.3 22.2 24.3 11.8 12.9 2.1 0.5 1.0 0.3 54.8 59.4 429.0 24.6 31.8 24.5 12.0 0.0 10.8 25.1 0.8 87.5 4.1 8.4 0.0 7.5 11.4 15.3 1.2 25.2 11.8 1.5 10.2 0.6 13.3 259.8 73.3 3.2 19.6 7.5 0.1 28.5 0.0 5.5 105.9 62.9 0.0 45.9 0.5 61.9 0.0 100.9 16.8 4.8 19.7 28.3 34.8 166.8 11.0 1.4 8.9 0.4 1.9 5.3 0.6 37.7 LBX1 "HPX6, LBX1H" ENSG00000138136 "Ladybird homeobox 1" P52954 10 101226195-101229794 "Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skeletal muscle: 26.5" "Cell type enriched" "Detected in single" 5 "Skeletal myocytes: 3.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebellum: 1.9;medulla oblongata: 3.5;pons: 2.5;spinal cord: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEK 293: 3.4;RH-30: 4.3;SCLC-21H: 9.1" "Group enriched" "Detected in some" 24 "cerebellum: 1.6;pons and medulla: 3.0" "Group enriched" "Detected in some" 18 "cerebellum: 1.2;medulla oblongata: 2.0;spinal cord: 2.0" "HPA002016, HPA002086, CAB079927" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB079927: , HPA002016: AB_2666518, HPA002086: AB_1079242" "unprognostic (4.13e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" "unprognostic (2.29e-1)" "unprognostic (7.28e-3)" "unprognostic (3.31e-1)" "unprognostic (9.76e-2)" "unprognostic (1.45e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.4 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.3 0.0 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.5 0.4 2.5 4.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LCE3A LEP13 ENSG00000185962 "Late cornified envelope 3A" Q5TA76 1 152622834-152623103 "Predicted intracellular proteins" Keratinization Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 107.7" "Cell type enhanced" "Detected in some" "Early spermatids: 3.2;Late spermatids: 1.5;Skeletal myocytes: 12.4;Spermatocytes: 1.6;Spermatogonia: 2.1" "Group enriched" "Detected in some" 9 "head and neck cancer: 26.6;melanoma: 9.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.4;LHCN-M2: 1.5;U-138 MG: 1.7" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (7.47e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 107.7 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 130.4" "Cell type enhanced" "Detected in many" "Adipocytes: 97.7;Endothelial cells: 80.5;Fibroblasts: 94.2;Hepatocytes: 175.2;Langerhans cells: 66.6;Microglial cells: 129.3" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "K-562: 114.7;RPTEC TERT1: 52.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" NA NA 8240000 14000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" 24.3 7.2 5.2 3.9 5.1 5.0 20.6 4.9 6.5 21.5 25.0 5.9 3.9 24.6 6.7 9.2 16.1 14.7 6.9 5.3 12.3 7.8 130.4 22.5 9.5 5.2 5.7 25.0 3.0 2.9 11.7 5.3 5.2 9.0 5.1 2.5 11.9 7.3 2.1 15.1 5.6 18.7 6.3 3.2 13.7 3.9 7.7 4.7 10.4 32.1 5.7 9.1 4.8 5.2 3.3 2.0 2.6 2.9 11.5 10.6 9.0 14.2 8.1 4.8 4.5 1.5 7.6 1.4 10.1 18.0 1.3 2.7 2.2 12.3 12.7 17.2 3.7 18.8 7.9 0.3 7.0 1.4 1.6 29.7 6.8 2.9 10.8 36.2 13.9 1.4 114.7 2.2 22.5 0.9 1.4 0.4 4.2 2.0 0.2 0.4 2.2 0.8 52.3 1.4 1.6 26.3 3.5 1.5 4.0 14.9 5.0 5.0 5.3 4.9 10.0 1.1 7.8 3.0 2.2 0.5 10.2 5.3 4.8 4.5 0.8 1.2 0.5 0.6 0.4 0.2 0.4 0.4 0.7 0.1 0.3 0.5 0.4 0.4 0.7 0.5 1.0 0.7 5.2 5.1 4.9 6.5 5.3 12.3 5.2 5.7 5.2 6.3 7.7 5.2 97.7 0.0 11.3 47.0 2.6 35.3 1.9 3.3 2.2 4.0 3.1 3.3 6.6 11.5 4.2 9.2 0.0 1.6 1.6 0.5 3.9 1.5 1.1 2.0 4.4 80.5 0.0 10.3 20.9 1.1 2.6 94.2 2.6 12.8 1.3 2.6 52.5 175.2 2.0 1.7 21.8 0.8 2.0 6.3 66.6 2.3 34.5 6.1 35.6 129.3 3.4 0.4 2.1 29.1 24.5 1.7 1.9 7.5 2.4 7.5 0.7 6.4 2.6 1.0 0.0 41.1 10.3 1.1 1.2 4.1 29.5 2.6 4.7 3.3 0.8 2.1 LHFPL6 "LHFP, MGC22429" ENSG00000183722 "LHFPL tetraspan subfamily member 6" Q9Y693 13 39209116-39603528 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 195.2;Endometrial stromal cells: 78.1;Extravillous trophoblasts: 156.9;Fibroblasts: 113.0;Smooth muscle cells: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "myeloid DC: 6.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.2" "Cell line enhanced" "Detected in many" "ASC diff: 255.1;HSkMC: 186.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058975 Approved Approved Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA058975: AB_2683866" "unprognostic (6.98e-2)" "unprognostic (2.71e-1)" "unprognostic (2.00e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (4.10e-2)" "unprognostic (5.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.76e-1)" "unprognostic (5.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (4.41e-3)" "unprognostic (5.25e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (2.30e-4)" 143.2 55.1 46.3 18.6 49.9 1.1 128.7 59.2 45.2 51.6 57.2 51.7 10.8 78.8 47.5 37.0 88.9 74.5 99.7 45.6 57.3 31.9 14.2 82.6 39.1 54.9 56.8 49.6 17.2 18.2 26.9 134.6 51.4 30.8 16.7 11.9 34.7 36.9 32.1 37.9 29.0 68.9 47.8 30.4 27.9 20.4 64.3 17.0 64.2 89.2 17.6 49.1 48.3 44.3 11.5 4.0 118.3 5.1 255.1 115.1 51.6 61.8 88.3 30.8 23.1 0.5 11.6 17.5 1.3 86.6 40.0 17.3 15.0 36.2 25.3 16.9 17.2 47.3 3.7 0.0 26.7 0.8 0.9 186.4 4.7 27.7 45.7 27.6 29.1 1.1 0.0 0.1 59.9 9.9 0.0 14.5 8.8 0.2 15.8 7.7 51.3 0.1 20.9 15.0 0.7 3.8 5.6 7.2 16.8 67.4 6.7 0.1 54.3 77.9 11.7 24.4 33.9 0.9 0.0 48.9 32.4 0.2 57.2 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.3 46.3 49.9 59.2 45.2 45.6 57.3 54.9 56.8 51.4 47.8 64.3 44.3 195.2 3.2 12.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.4 28.6 0.0 0.0 9.9 0.0 0.0 5.0 1.4 0.0 1.9 0.6 0.0 2.7 78.1 32.0 0.0 0.0 0.0 0.6 156.9 113.0 0.0 2.8 2.5 22.1 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 3.6 2.2 0.0 0.0 0.0 131.6 0.0 0.0 0.0 0.0 6.2 1.2 45.8 0.0 0.0 LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78757094 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;ovary: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Fibroblasts: 4.2;Leydig cells: 20.2;Oligodendrocyte precursor cells: 3.5;Skeletal myocytes: 3.6" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 6.3" "Lineage enriched" "Detected in single" 19 "granulocytes: 6.3" "Cell line enhanced" "Detected in some" "AF22: 9.3;NTERA-2: 15.2;RH-30: 6.4;U-937: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" 0.5 0.0 1.8 0.4 1.3 0.3 0.8 1.1 1.7 0.6 1.1 0.3 0.0 1.1 0.3 0.6 0.3 0.8 0.7 3.0 1.2 0.1 0.1 0.1 0.0 1.8 1.7 3.6 0.4 0.0 0.1 0.0 1.3 0.2 0.4 0.1 0.3 0.1 0.0 0.5 0.3 0.5 2.6 0.1 0.4 0.3 1.1 0.7 0.1 0.3 0.4 0.3 0.2 3.8 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.6 1.0 1.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 2.1 0.0 0.4 1.7 15.2 0.0 0.2 0.8 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 2.6 0.0 0.0 0.2 0.0 0.6 1.2 0.0 0.7 0.7 3.7 1.5 6.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 1.3 1.1 1.7 3.0 1.2 1.8 1.7 1.3 2.6 1.1 3.8 1.2 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.5 20.2 0.1 1.8 1.0 0.6 1.0 0.0 3.5 0.1 0.0 0.0 2.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 3.6 0.4 0.0 0.3 1.5 0.4 0.0 0.4 0.2 0.0 0.2 LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Endocytosis "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.4;Hepatocytes: 188.4;Leydig cells: 233.3;Peritubular cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Cell line enhanced" "Detected in many" "ASC diff: 484.8;ASC TERT1: 488.4;fHDF/TERT166: 222.2;HSkMC: 318.5;hTERT-RPE1: 248.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" 109.2 14.1 21.3 29.0 36.3 8.2 40.0 30.2 19.7 32.3 8.0 24.1 23.2 36.9 6.2 19.3 30.3 31.5 35.5 16.7 21.9 5.7 35.0 34.0 4.9 46.0 31.5 71.0 10.7 7.8 10.2 39.8 27.9 13.8 11.2 9.9 20.3 20.2 13.0 20.4 18.4 28.9 27.1 13.6 15.1 7.3 48.9 5.6 17.6 23.5 2.7 25.5 29.3 27.6 7.7 14.5 30.4 24.2 484.8 488.4 91.2 85.3 109.0 27.5 26.7 26.9 12.4 0.4 10.4 222.2 6.0 33.6 5.3 8.7 9.7 0.7 1.3 0.4 17.9 56.4 66.5 0.5 14.6 318.5 3.1 61.8 7.2 248.7 1.7 1.1 0.4 1.3 87.2 1.7 0.2 0.4 34.8 11.0 8.8 3.2 171.0 1.6 1.9 2.2 1.4 16.4 19.0 0.6 13.2 42.0 2.9 1.2 1.2 96.0 35.0 53.9 5.2 1.1 0.1 0.2 167.4 0.1 18.7 0.0 4.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 1.6 21.3 36.3 30.2 19.7 16.7 21.9 46.0 31.5 27.9 27.1 48.9 27.6 24.6 12.8 8.4 113.6 3.2 24.0 11.9 28.7 19.9 29.2 4.9 19.3 14.8 15.7 14.7 1.8 0.0 87.5 1.1 81.7 0.0 7.4 1.9 9.7 111.4 13.0 4.2 0.8 39.3 1.8 53.0 273.4 49.5 4.2 6.3 36.9 11.0 188.4 73.8 8.4 41.6 14.1 6.1 145.3 28.6 8.4 233.3 102.9 28.4 89.9 48.8 154.7 1.0 173.4 6.6 14.7 27.2 184.3 4.4 5.5 86.0 2.1 15.1 7.3 39.5 129.7 77.0 1.6 2.4 35.4 16.1 125.9 4.2 11.4 25.0 12.3 LRP3 "hLRp105, LRP-3" ENSG00000130881 "LDL receptor related protein 3" O75074 19 33177603-33208864 "Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.2;Muller glia cells: 29.9;Peritubular cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041658 Approved "Lipid droplets" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Lipid droplets" "HPA041658: " "unprognostic (3.10e-1)" "unprognostic (2.55e-2)" "unprognostic (3.25e-2)" "unprognostic (1.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (1.39e-1)" "unprognostic (3.14e-2)" "unprognostic (3.07e-2)" "unprognostic (4.67e-2)" "prognostic favorable (6.12e-7)" "unprognostic (1.34e-1)" "unprognostic (2.71e-3)" "unprognostic (4.36e-1)" "unprognostic (2.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.32e-1)" 28.1 28.2 44.7 5.1 47.2 18.7 23.8 15.2 61.2 27.0 0.0 25.7 7.1 27.0 8.5 8.5 21.4 8.4 19.1 53.2 22.6 11.0 39.3 13.0 2.6 21.4 25.8 69.8 17.6 16.7 26.9 3.5 20.8 25.9 3.0 2.4 16.8 12.0 28.7 14.2 10.2 10.3 17.0 6.8 17.3 8.6 31.6 1.7 20.4 17.6 0.9 24.3 15.6 25.7 0.1 48.6 13.1 47.9 32.2 12.1 9.0 12.4 12.0 11.1 4.3 14.0 0.6 0.0 31.6 15.4 16.0 0.0 12.6 1.3 0.9 0.2 23.8 0.0 10.7 49.1 12.3 17.8 1.6 18.2 11.1 3.1 1.7 1.9 9.3 0.0 0.1 0.0 14.4 45.2 0.1 19.6 27.0 9.7 2.0 0.0 6.0 0.1 0.0 19.4 28.8 43.3 20.0 0.1 3.5 1.4 20.0 61.5 0.0 23.5 20.4 35.6 7.1 0.0 0.0 0.2 0.0 30.0 7.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.1 44.7 47.2 15.2 61.2 53.2 22.6 21.4 25.8 20.8 17.0 31.6 25.7 4.4 0.0 3.6 18.9 1.1 3.3 2.6 1.4 4.0 30.2 12.8 13.7 0.5 14.3 3.5 5.5 4.2 0.2 0.4 1.3 0.0 5.8 2.7 5.4 17.6 3.0 1.8 5.7 19.5 7.8 0.7 24.9 0.5 10.7 0.0 19.2 6.1 28.3 10.3 23.5 19.4 6.4 0.0 8.8 2.7 6.4 26.1 5.0 3.6 4.7 5.8 29.9 0.0 15.1 1.7 5.9 1.0 32.7 0.1 8.2 0.7 0.6 0.3 4.2 6.6 6.8 13.7 0.2 2.8 2.3 2.6 0.0 0.6 9.8 6.0 1.9 LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 62.1;Leydig cells: 27.1;Melanocytes: 33.8;Peritubular cells: 17.3;Skeletal myocytes: 33.0" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.7;ASC TERT1: 25.3;HHSteC: 19.8;HSkMC: 10.6;LHCN-M2: 13.4" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" 23.3 6.6 0.4 2.5 0.4 0.5 16.0 1.5 1.3 22.4 2.6 15.1 1.8 29.7 3.7 4.5 18.2 3.6 7.2 0.6 0.6 1.0 0.1 3.5 0.5 0.5 0.3 21.0 1.1 0.3 1.7 0.7 0.4 6.1 2.1 0.4 5.5 5.8 4.8 10.6 7.2 9.1 0.2 0.2 8.2 1.5 0.5 0.4 4.2 5.6 0.3 9.7 16.1 0.7 0.0 0.1 0.2 0.3 7.7 25.3 0.3 2.8 4.0 0.3 1.4 0.2 0.1 0.2 0.3 4.6 0.1 0.3 0.1 0.0 0.4 0.2 0.2 0.5 0.2 0.2 19.8 0.2 0.2 10.6 0.1 0.6 0.0 0.2 0.1 0.4 0.3 0.1 13.4 0.1 0.3 0.6 0.6 0.1 0.1 0.1 1.7 0.3 0.0 0.2 0.8 0.3 0.4 0.3 0.8 0.1 0.2 0.3 0.3 2.4 0.2 2.7 0.1 0.2 0.2 0.3 1.5 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.0 0.4 0.4 1.5 1.3 0.6 0.6 0.5 0.3 0.4 0.2 0.5 0.7 4.0 0.0 1.8 0.0 0.1 6.6 2.1 0.0 0.0 2.1 0.5 0.8 1.5 0.0 0.6 0.0 2.1 0.1 0.2 0.0 0.0 0.0 1.0 0.5 11.0 3.7 1.2 0.0 0.1 0.0 0.2 62.1 0.5 0.4 1.3 0.2 1.4 0.1 0.4 1.7 0.3 0.3 0.0 0.6 8.3 0.5 27.1 1.1 33.8 1.9 0.1 0.2 1.0 0.0 0.1 0.0 0.1 17.3 0.4 1.4 0.1 0.3 0.0 1.0 0.0 33.0 2.8 0.4 0.3 0.5 7.0 0.1 1.1 1.2 0.1 1.3 LTBP2 "C14orf141, LTBP3" ENSG00000119681 "Latent transforming growth factor beta binding protein 2" Q14767 14 74498183-74612378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Disease variant, Dwarfism, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 60.6;Fibroblasts: 59.5;Peritubular cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 240.8;HUVEC TERT2: 129.1;LHCN-M2: 129.4;TIME: 564.5" "Group enriched" "Detected in some" 10 "cerebellum: 5.3;olfactory bulb: 2.4" "Region enhanced" "Detected in many" "olfactory bulb: 15.4" HPA003415 Approved Approved Nucleoplasm "Secreted to extracellular matrix" NA NA 14000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003415: AB_1079284" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (5.10e-2)" "unprognostic (3.92e-3)" "unprognostic (2.08e-3)" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (4.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (3.77e-1)" "unprognostic (1.98e-3)" "unprognostic (2.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.94e-4)" 34.2 4.0 1.1 15.2 2.9 0.6 24.4 4.1 5.6 66.2 9.5 6.6 3.1 22.5 23.9 10.7 11.7 33.1 45.4 1.2 1.1 4.1 2.1 64.9 8.3 2.2 1.1 39.4 8.7 9.6 7.3 28.0 1.4 15.7 2.6 2.3 26.7 19.6 13.6 12.6 6.9 16.0 2.2 3.9 8.5 5.4 1.9 3.1 53.0 21.4 6.1 14.2 21.6 1.0 2.5 4.9 1.2 0.2 36.9 67.7 0.2 47.4 16.2 9.2 5.7 0.0 17.4 0.4 13.8 240.8 4.1 4.8 0.2 17.7 3.8 0.2 0.8 0.8 2.2 2.1 8.8 0.1 0.6 70.2 7.7 50.7 29.1 68.9 129.1 0.1 0.2 0.1 129.4 1.1 0.1 0.3 0.3 0.2 4.5 0.5 1.1 0.1 11.3 6.7 1.0 3.3 33.1 0.1 1.1 3.4 1.1 0.2 564.5 3.3 54.0 17.0 18.0 0.7 0.7 0.1 13.1 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 2.9 4.1 5.6 1.2 1.1 2.2 1.1 1.4 2.2 1.9 1.0 3.8 0.0 2.2 2.3 0.1 5.6 15.1 13.0 13.1 2.1 1.9 60.6 6.4 0.0 6.1 0.0 0.0 0.5 1.2 0.1 5.9 1.4 1.2 0.5 7.9 6.5 0.0 5.7 1.1 0.4 0.3 59.5 1.5 0.9 1.3 1.9 9.3 0.4 4.2 3.3 0.7 0.0 20.3 0.3 5.8 5.8 16.4 3.7 0.0 22.5 0.1 0.4 0.0 1.0 0.3 4.4 0.0 82.4 0.3 10.7 0.0 0.0 0.3 1.0 6.6 3.2 10.8 2.8 3.8 5.2 1.0 1.2 0.9 2.2 0.1 2.1 LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 61.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 293.8;U-87 MG: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" 65.4 80.1 44.0 21.4 46.1 11.2 68.0 42.0 56.1 120.0 42.2 103.7 16.8 130.8 36.7 36.7 112.6 39.9 131.2 37.6 41.4 84.5 48.8 72.2 24.7 57.0 49.0 155.5 70.1 44.7 111.0 25.5 45.4 109.0 8.5 12.8 64.2 56.3 54.6 39.6 55.8 35.7 51.7 58.1 62.0 20.3 46.9 17.6 114.0 31.0 12.1 84.9 88.0 54.0 16.5 65.9 8.7 43.2 60.7 97.0 8.5 64.7 43.6 8.2 5.3 25.3 85.5 2.0 53.6 64.2 20.4 71.9 11.8 12.2 3.7 9.5 26.4 15.9 25.2 26.2 40.3 2.2 13.4 109.9 4.9 12.1 1.5 293.8 31.9 5.2 4.9 12.7 6.0 39.4 10.9 5.9 7.6 14.6 81.2 29.3 1.1 32.1 6.7 5.5 2.9 41.8 17.3 24.9 35.3 3.7 46.0 5.8 107.0 24.8 32.2 42.5 17.6 13.9 27.1 1.4 157.8 2.6 52.3 0.2 7.3 2.9 8.8 11.2 14.1 61.2 12.6 10.4 8.9 47.6 10.5 11.2 2.9 10.8 13.2 17.8 14.2 7.8 44.0 46.1 42.0 56.1 37.6 41.4 57.0 49.0 45.4 51.7 46.9 54.0 47.1 12.8 11.7 64.0 26.8 73.8 27.7 22.0 50.7 55.7 42.2 43.1 16.7 35.8 16.2 40.5 2.1 24.7 24.4 19.7 21.5 28.1 1.1 19.3 37.5 29.8 30.6 11.2 21.3 12.0 10.5 86.1 14.8 25.3 24.1 92.5 37.5 61.6 20.7 28.6 17.9 15.1 8.2 11.0 34.4 4.3 86.6 14.6 30.2 17.8 11.5 71.4 24.7 29.7 20.2 18.1 15.0 123.8 20.9 35.8 25.3 15.7 8.2 14.3 39.5 89.4 44.0 9.5 37.5 46.9 79.3 16.3 24.4 26.0 20.4 26.5 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LVRN "APQ, AQPEP, FLJ90650, TAQPEP" ENSG00000172901 Laeverin Q6Q4G3 5 115962454-116027619 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 11.1;placenta: 21.8" "Group enriched" "Detected in some" 4 "Early spermatids: 29.3;Extravillous trophoblasts: 33.1;Late spermatids: 68.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 2.5" HPA053254 Enhanced "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 50: Fibroblasts - ECM organization" "HPA053254: AB_2682092" "unprognostic (1.47e-1)" "unprognostic (3.38e-3)" "unprognostic (5.81e-2)" "unprognostic (2.97e-3)" "unprognostic (5.38e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-3)" "unprognostic (1.88e-2)" "unprognostic (2.23e-1)" "unprognostic (2.23e-2)" "unprognostic (3.83e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-7)" "unprognostic (1.05e-2)" "unprognostic (5.94e-2)" "unprognostic (6.53e-2)" "unprognostic (3.31e-2)" 11.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 21.8 0.0 0.0 0.4 0.0 0.2 0.1 0.3 0.4 0.8 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 1.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 29.3 0.0 0.1 0.1 0.0 0.0 2.1 0.0 33.1 7.9 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 68.1 4.7 0.3 0.0 1.9 0.0 0.0 0.0 3.0 1.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.3 0.3 0.1 0.0 10.7 0.0 1.0 0.0 0.1 MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25616791-25786206 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;Excitatory neurons: 72.8;Hepatic stellate cells: 63.9;Hepatocytes: 57.8;Inhibitory neurons: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.7" "Lineage enriched" "Detected in single" 5 "T-cells: 4.7" "Cell line enhanced" "Detected in many" "AF22: 30.5;HSkMC: 108.9;U-266/70: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA048352: AB_2680368" "unprognostic (2.75e-1)" "unprognostic (5.45e-3)" "unprognostic (5.71e-3)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (8.90e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.55e-4)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "prognostic favorable (4.79e-4)" "unprognostic (2.51e-1)" "unprognostic (9.09e-3)" "unprognostic (3.18e-2)" "unprognostic (7.23e-2)" "unprognostic (7.44e-2)" "unprognostic (5.18e-2)" 12.5 11.6 13.3 9.4 15.2 2.2 6.2 16.6 16.1 19.6 27.3 10.0 4.5 14.5 7.5 7.0 9.7 18.6 10.1 15.9 16.9 25.4 29.6 9.2 12.4 45.1 23.2 17.3 3.6 24.0 17.1 21.1 26.1 17.6 4.6 11.0 5.7 17.9 4.6 8.1 6.1 19.9 29.4 19.3 7.3 4.2 16.4 10.5 26.0 5.5 9.4 12.3 9.1 37.8 0.1 0.4 30.5 6.4 22.4 17.2 8.6 0.4 5.8 1.4 0.4 0.6 0.2 0.1 0.3 2.3 3.9 0.4 3.0 0.3 0.6 9.8 1.3 0.6 0.5 0.1 2.6 5.2 12.0 108.9 0.5 0.7 0.0 0.4 0.1 1.2 0.1 1.3 0.0 1.6 0.0 5.8 7.8 0.1 0.2 0.6 18.9 0.6 0.2 0.7 17.7 0.6 0.7 4.7 1.5 5.5 2.4 3.6 0.1 0.0 1.6 20.1 0.7 31.7 0.1 0.1 4.6 10.7 1.5 0.3 0.9 0.4 0.3 0.6 0.5 0.2 2.1 0.9 0.3 0.5 4.7 2.7 0.6 0.4 0.8 0.2 0.5 0.7 13.3 15.2 16.6 16.1 15.9 16.9 45.1 23.2 26.1 29.4 16.4 37.8 5.8 3.2 3.2 18.3 2.0 6.6 2.9 3.6 5.2 23.5 1.1 1.5 7.0 4.3 7.3 22.0 54.2 10.6 1.6 0.5 9.8 1.0 0.3 0.4 8.1 8.4 3.0 2.7 72.8 3.8 0.9 23.3 1.1 0.6 2.5 0.3 63.9 57.8 24.8 21.9 65.8 0.1 16.2 19.0 4.3 2.1 27.1 6.8 1.8 39.4 3.3 17.8 3.1 25.1 21.7 1.4 0.3 22.2 2.2 2.0 0.0 23.3 2.2 4.4 6.6 17.0 7.1 0.2 2.9 1.0 5.3 42.7 6.9 0.7 0.2 1.9 MAP1LC3C ATG8J ENSG00000197769 "Microtubule associated protein 1 light chain 3 gamma" Q9BXW4 1 241995490-241999098 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.6;breast: 13.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.4;granulocytes: 1.3" "Cancer enhanced" "Detected in many" "glioma: 2.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SuSa: 28.0" "Low region specificity" "Detected in all" HPA072670 Supported "Cytoplasmic bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Cytoplasmic bodies" "HPA072670: AB_2686546" "unprognostic (2.27e-2)" "unprognostic (1.74e-1)" "unprognostic (9.44e-3)" "prognostic unfavorable (1.34e-7)" "unprognostic (1.08e-1)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (3.73e-2)" "unprognostic (1.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (2.89e-3)" "unprognostic (6.17e-3)" "unprognostic (1.26e-1)" "unprognostic (8.65e-2)" "unprognostic (7.73e-2)" 13.6 0.6 0.7 0.7 0.8 0.1 13.9 0.7 2.0 0.3 1.0 1.9 0.2 0.4 0.2 1.6 4.6 0.5 0.7 0.8 0.6 0.4 0.3 5.9 4.6 0.8 0.7 3.2 0.4 0.6 0.7 10.7 0.8 0.2 0.3 0.0 7.7 0.1 3.7 5.6 2.8 0.7 0.5 0.9 4.6 0.3 0.9 0.5 1.7 3.4 3.8 2.2 1.0 0.8 0.1 0.1 5.9 0.0 0.2 5.4 3.8 0.1 0.0 0.0 0.2 0.5 0.0 0.0 3.3 1.3 0.3 0.0 0.1 0.0 0.0 0.0 1.1 0.2 0.2 0.2 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.2 1.8 0.1 0.0 0.0 1.3 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.3 28.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.7 0.8 0.7 2.0 0.8 0.6 0.8 0.7 0.8 0.5 0.9 0.8 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAP7D3 FLJ12649 ENSG00000129680 "MAP7 domain containing 3" Q8IWC1 X 136213220-136256482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 264.2;Late spermatids: 288.5;Spermatogonia: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035598, HPA058101" Approved Uncertain Centrosome,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Centrosome Cytosol "HPA035598: AB_10671108, HPA058101: AB_2683604" "unprognostic (2.89e-1)" "unprognostic (1.23e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (9.00e-5)" "unprognostic (8.83e-3)" "unprognostic (3.77e-3)" "unprognostic (4.16e-5)" "unprognostic (5.35e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (9.91e-2)" "prognostic unfavorable (7.91e-4)" "unprognostic (2.04e-1)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.38e-5)" 18.1 4.5 1.4 5.8 1.5 5.0 11.4 1.2 1.8 7.4 2.9 8.3 2.2 9.7 6.1 6.1 13.2 6.0 8.7 1.2 1.7 3.7 4.1 5.9 6.6 1.8 1.6 16.8 2.1 5.8 4.7 7.1 2.0 3.7 3.3 1.5 3.0 4.1 11.5 4.5 5.6 8.8 1.5 6.3 5.0 15.8 1.8 5.3 8.2 9.1 5.0 7.7 6.4 1.9 33.6 11.8 8.7 15.0 19.3 20.1 12.1 31.6 17.4 25.3 34.6 11.7 16.5 17.3 50.0 27.9 26.8 15.7 25.6 16.9 33.5 15.9 25.6 10.3 18.0 0.0 21.0 25.2 10.2 41.1 9.5 26.0 32.0 14.2 20.0 28.1 9.0 26.1 18.8 20.9 30.4 10.2 12.4 8.1 0.3 29.5 23.5 8.4 0.8 5.1 6.1 13.0 18.4 6.7 11.4 14.5 0.1 11.5 60.3 26.9 15.5 34.6 40.6 17.8 22.7 19.3 18.5 42.3 13.0 6.6 3.5 1.1 5.2 4.2 6.5 7.5 4.9 5.8 4.4 6.4 5.2 4.1 0.7 6.6 7.9 4.6 3.8 2.9 1.4 1.5 1.2 1.8 1.2 1.7 1.8 1.6 2.0 1.5 1.8 1.9 36.6 16.0 6.7 4.2 18.5 7.1 7.2 15.4 14.8 0.7 5.1 9.1 41.5 11.5 8.7 18.4 0.0 10.3 13.8 3.7 1.9 8.6 264.2 13.7 47.3 24.9 5.4 12.6 1.9 14.7 103.4 46.5 2.0 5.1 35.5 15.2 50.7 30.4 15.4 20.2 1.0 2.8 8.2 17.3 7.8 288.5 63.3 15.0 7.2 5.6 23.4 12.2 22.6 1.5 3.6 13.0 14.1 47.8 10.0 13.5 0.7 54.6 6.5 2.9 39.5 29.8 61.5 53.2 106.9 5.3 4.8 13.4 18.6 15.9 3.3 2.4 MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857345-113863475 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 12.7;neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 405.8;TIME: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022062, HPA054820, HPA067595, HPA069443" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 19000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB022062: AB_309681, HPA054820: AB_2682613, HPA067595: AB_2732772, HPA069443: AB_2732133" "unprognostic (4.71e-1)" "unprognostic (1.91e-2)" "unprognostic (2.46e-1)" "unprognostic (5.51e-3)" "unprognostic (8.22e-3)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.78e-8)" "unprognostic (7.82e-2)" "unprognostic (2.57e-1)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.36e-3)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "unprognostic (2.70e-2)" 42.8 16.8 65.1 58.2 64.1 104.6 50.2 73.2 78.5 31.9 21.6 75.7 38.9 31.2 13.5 45.1 27.3 35.8 18.2 56.8 89.2 24.6 26.1 35.0 45.4 81.0 87.6 39.0 42.4 7.0 20.6 63.0 73.1 37.8 68.2 22.0 28.0 18.0 15.7 32.1 43.3 30.1 106.8 57.0 62.8 10.3 85.5 44.8 16.2 12.9 45.3 86.2 34.5 102.8 39.2 22.6 405.8 22.3 134.0 86.6 2.2 123.0 171.4 84.9 140.6 40.7 54.1 0.1 25.3 228.0 67.3 118.0 67.9 35.7 109.7 0.3 40.2 0.0 22.2 53.3 89.2 10.3 0.7 90.2 68.8 81.8 77.4 231.9 243.1 0.4 4.6 107.6 122.1 0.4 1.3 0.3 52.7 43.5 29.4 0.2 40.7 4.1 26.9 73.6 56.4 163.4 78.7 39.6 89.6 95.0 2.1 11.3 326.0 78.3 0.5 129.9 212.7 288.3 22.4 11.4 60.2 55.8 153.4 0.0 3.9 0.0 0.0 12.7 0.0 4.6 0.0 0.0 1.1 1.9 0.0 0.0 18.7 0.0 7.5 0.0 0.0 0.5 65.1 64.1 73.2 78.5 56.8 89.2 81.0 87.6 73.1 106.8 85.5 102.8 211.2 9.6 15.5 44.7 139.0 504.1 540.7 232.3 275.4 157.0 213.2 176.7 16.6 57.2 115.0 38.6 29.2 7.2 5.5 629.5 37.2 144.3 55.7 111.2 444.0 271.6 336.3 2.5 33.0 229.9 11.2 372.6 135.1 130.4 2.5 526.1 236.0 8.8 371.6 84.1 21.0 369.4 126.1 286.3 605.5 35.7 120.5 381.3 273.9 60.0 447.2 315.5 2.1 194.5 9.7 208.1 223.1 67.0 105.2 380.1 89.9 6.9 145.0 37.7 39.5 89.8 222.8 22.7 16.2 326.3 638.5 29.4 22.3 62.3 352.3 620.2 MAS1 ENSG00000130368 "MAS1 proto-oncogene, G protein-coupled receptor" P04201 6 159890988-159917447 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "brain: 9.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;B-cells: 2.0;Cone photoreceptor cells: 2.1;Rod photoreceptor cells: 2.1;Urothelial cells: 1.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 5.1;hippocampal formation: 9.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HMC-1: 7.5" "Group enriched" "Detected in many" 22 "amygdala: 38.5;basal ganglia: 26.6;cerebral cortex: 32.4;hippocampal formation: 64.6;white matter: 18.1" "Group enriched" "Detected in some" 4 "amygdala: 5.2;cerebral cortex: 8.0;hippocampal formation: 15.1" HPA079325 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA079325: " "unprognostic (3.31e-1)" "unprognostic (2.25e-3)" "unprognostic (2.91e-1)" "unprognostic (2.22e-3)" "unprognostic (8.15e-3)" "unprognostic (7.05e-2)" "unprognostic (1.88e-1)" "unprognostic (5.53e-2)" "unprognostic (6.52e-2)" "unprognostic (1.48e-5)" "unprognostic (1.69e-1)" "unprognostic (7.67e-2)" "unprognostic (6.28e-1)" 0.0 0.0 1.7 0.0 0.7 0.3 0.0 0.0 5.1 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.7 0.0 5.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 3.2 0.6 0.0 2.0 0.0 1.4 0.0 0.0 1.2 0.1 0.3 0.8 0.0 0.6 0.0 2.1 0.2 0.2 0.0 0.0 0.0 0.1 0.4 0.3 0.8 0.0 0.0 0.1 0.0 0.3 0.7 0.0 0.3 0.0 0.4 1.1 0.4 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.9 0.7 0.0 0.0 0.5 0.7 1.0 0.0 0.0 0.1 0.0 0.7 0.0 1.4 0.0 0.3 0.0 2.1 0.0 1.3 1.0 0.4 0.5 0.0 0.0 0.3 0.5 0.2 0.2 1.9 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cardiomyocytes: 38.1;Cholangiocytes: 20.0;Endometrial stromal cells: 30.6;Fibroblasts: 16.4;Hepatic stellate cells: 23.2;Hepatocytes: 65.8" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 133.3;BJ hTERT+: 498.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 6.3 3.6 9.4 1.3 9.4 0.0 2.8 12.9 7.0 120.0 4.9 57.5 1.9 88.4 3.3 11.1 17.7 5.1 116.1 10.4 27.0 4.8 183.4 6.0 1.0 19.2 16.5 2.7 0.2 0.3 1.0 9.0 15.3 46.0 5.6 0.0 2.3 52.2 37.5 6.3 7.5 44.4 22.2 0.8 1.6 0.5 14.6 0.2 3.2 18.9 4.3 9.9 61.5 32.0 0.0 0.0 0.3 0.4 15.7 17.3 0.1 133.3 498.3 1.8 0.9 0.0 0.0 0.1 0.0 40.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.2 0.0 0.0 5.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.4 12.9 7.0 10.4 27.0 19.2 16.5 15.3 22.2 14.6 32.0 1.1 0.0 1.8 28.1 0.2 2.9 0.1 0.2 0.0 0.0 0.0 0.0 38.1 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.7 30.6 2.0 0.0 0.0 0.2 0.0 0.3 16.4 0.0 0.7 0.0 0.2 23.2 65.8 0.4 0.0 0.9 0.0 0.0 1.9 3.7 7.5 2.5 0.3 1.8 1.0 0.0 0.0 0.0 10.1 0.2 0.0 0.0 0.7 0.1 0.1 0.0 2.4 0.0 0.0 0.0 5.4 4.5 0.0 0.0 0.2 1.7 0.1 0.5 5.1 0.0 0.1 MATN4 ENSG00000124159 "Matrilin 4" O95460 20 45293445-45308529 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "pancreas: 24.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Fibroblasts: 8.5;Langerhans cells: 6.3;Spermatogonia: 4.9;Suprabasal keratinocytes: 4.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 2.5;U-937: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 14000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.54e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-2)" "unprognostic (8.38e-2)" "unprognostic (9.67e-2)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (6.27e-2)" "unprognostic (6.74e-3)" "unprognostic (5.53e-1)" "unprognostic (6.19e-3)" "unprognostic (3.63e-6)" "unprognostic (2.38e-1)" "unprognostic (4.69e-2)" "unprognostic (4.27e-1)" "unprognostic (5.38e-2)" 0.7 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 24.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 6.4 0.7 1.0 0.0 0.0 1.6 1.9 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.1 0.7 0.2 0.4 0.0 0.0 1.0 2.5 0.0 8.5 1.1 0.8 0.0 0.3 0.4 0.2 0.1 0.0 0.4 0.1 0.0 0.0 6.3 0.5 0.0 0.1 1.8 1.0 0.0 0.0 0.0 3.0 0.4 0.9 0.1 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.4 0.4 1.6 4.9 0.3 4.3 0.3 0.3 0.1 0.2 1.0 MCOLN3 "FLJ11006, TRP-ML3, TRPML3" ENSG00000055732 "Mucolipin 3" Q8TDD5 1 85018082-85048500 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 43.5;epididymis: 13.9;parathyroid gland: 35.3" "Group enriched" "Detected in many" 7 "Enteroendocrine cells: 113.6;Melanocytes: 151.2" "Cancer enriched" "Detected in many" 6 "melanoma: 8.0" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.0;hippocampal formation: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.9;HAP1: 12.7;RH-30: 15.7;SK-MEL-30: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018106, HPA062137" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA018106: AB_1853647, HPA062137: AB_2684695" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-2)" "unprognostic (3.21e-5)" "unprognostic (2.25e-1)" "unprognostic (8.80e-3)" "unprognostic (3.97e-3)" "unprognostic (1.13e-1)" "unprognostic (2.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.45e-3)" "unprognostic (3.09e-2)" "unprognostic (7.32e-5)" "unprognostic (6.36e-3)" "unprognostic (2.61e-1)" "unprognostic (6.11e-2)" "unprognostic (6.43e-2)" 3.0 43.5 0.7 0.2 0.2 0.0 2.2 0.0 4.0 5.1 3.3 1.0 5.4 5.7 13.9 0.3 1.7 0.3 4.4 3.5 0.1 5.0 0.1 4.5 0.1 0.0 0.1 2.1 7.4 35.3 7.0 2.5 0.1 0.3 1.0 0.1 3.7 0.6 0.2 4.3 2.2 1.9 0.2 0.9 2.6 0.6 0.5 4.3 1.9 1.1 0.2 0.4 2.4 0.0 9.0 2.0 0.0 0.0 6.6 5.9 2.4 0.1 12.9 3.2 8.8 0.6 1.5 0.0 0.9 0.1 3.0 0.0 12.7 4.2 2.0 3.6 8.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 1.5 2.6 1.5 3.2 0.0 0.0 0.0 0.0 6.3 0.7 0.0 0.0 1.0 0.0 1.1 0.0 15.7 0.0 0.4 0.0 0.5 0.0 0.4 0.0 29.3 0.9 5.2 6.5 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 4.0 3.5 0.1 0.0 0.1 0.1 0.2 0.5 0.0 16.6 16.0 1.7 0.0 0.0 8.7 3.5 7.0 0.6 0.0 4.2 1.9 6.8 11.5 2.5 3.7 0.0 9.0 0.1 0.3 0.0 1.7 0.4 0.8 8.1 2.0 113.6 0.0 1.2 9.6 0.2 18.4 1.5 1.9 0.0 0.3 0.0 0.1 3.5 0.0 0.4 2.5 6.1 0.0 7.1 0.1 1.8 3.2 151.2 2.8 1.6 0.0 0.0 0.0 0.1 3.6 12.9 0.0 0.3 1.4 4.1 3.4 0.7 0.0 6.6 6.3 1.2 1.8 4.1 0.4 3.4 2.6 1.4 1.0 3.8 0.6 MEDAG "AWMS3, C13orf33, FLJ14834, MEDA-4" ENSG00000102802 "Mesenteric estrogen dependent adipogenesis" Q5VYS4 13 30906271-30925572 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 163.7" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 80.2;Fibroblasts: 122.4;Skeletal myocytes: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 312.4;ASC TERT1: 87.4;U-2197: 175.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.44e-2)" "unprognostic (3.42e-2)" "unprognostic (6.06e-3)" "unprognostic (8.80e-2)" "unprognostic (1.07e-1)" "unprognostic (3.71e-3)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (8.69e-3)" "unprognostic (2.48e-1)" "unprognostic (5.41e-3)" "unprognostic (7.52e-2)" 163.7 4.0 0.6 15.8 0.8 0.3 57.0 0.5 1.5 19.1 4.6 14.5 2.5 28.1 26.9 8.4 36.3 15.1 30.1 0.6 1.9 11.6 0.8 16.0 1.5 0.7 0.8 11.8 14.2 0.8 6.1 6.8 0.7 7.5 6.5 0.1 15.5 2.5 14.8 21.4 11.5 23.4 0.7 0.4 15.4 7.0 1.1 1.9 26.8 6.2 0.8 66.4 10.1 0.5 0.0 0.0 0.0 0.0 312.4 87.4 0.0 0.6 0.1 1.3 1.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 0.5 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.1 37.1 0.0 45.9 0.0 0.2 42.7 0.0 0.0 0.0 4.2 0.0 0.0 0.2 4.0 0.0 0.0 0.0 37.9 0.0 0.0 0.0 6.6 0.0 0.0 0.3 0.0 6.0 0.1 0.0 46.9 0.0 0.2 175.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.5 1.5 0.6 1.9 0.7 0.8 0.7 0.7 1.1 0.5 12.0 0.0 0.5 0.3 0.0 11.5 0.2 0.1 0.0 0.0 0.1 0.3 4.5 5.7 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.9 1.1 2.0 80.2 13.9 0.0 0.0 0.4 0.0 0.5 122.4 2.0 1.7 0.0 0.0 2.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 20.6 2.2 19.0 1.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 0.1 1.7 0.0 0.2 0.7 0.0 0.0 80.4 19.6 0.0 0.0 0.7 10.4 0.3 1.1 5.3 0.0 0.6 METTL2B "FLJ11350, METL, METTL2" ENSG00000165055 "Methyltransferase like 2B" Q6P1Q9 7 128476729-128506602 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "unprognostic (4.00e-1)" "unprognostic (2.95e-1)" "unprognostic (1.85e-1)" "unprognostic (1.81e-3)" "unprognostic (9.91e-2)" "unprognostic (1.21e-1)" "unprognostic (4.36e-2)" "unprognostic (3.40e-2)" "unprognostic (4.57e-2)" "unprognostic (1.37e-1)" "unprognostic (1.35e-3)" "unprognostic (3.46e-2)" "unprognostic (8.38e-2)" "unprognostic (5.67e-2)" 7.1 7.0 3.2 3.3 3.6 3.2 6.3 5.3 4.9 5.6 1.6 6.4 2.5 6.5 5.2 7.7 5.6 1.9 7.9 2.5 3.7 6.9 10.0 5.2 3.8 3.0 3.1 5.7 7.7 2.8 5.3 3.7 3.1 5.4 4.2 6.3 6.1 2.5 11.4 7.9 5.6 3.4 1.5 5.8 6.3 3.8 3.7 2.7 4.8 3.6 4.2 6.0 5.6 5.1 9.1 11.6 8.5 14.6 6.1 6.9 5.6 8.1 4.6 7.5 6.2 11.5 10.7 8.5 3.0 8.0 13.6 9.9 13.2 7.7 10.8 8.2 12.0 10.6 15.7 9.4 9.7 13.1 7.4 6.1 8.8 9.6 8.9 7.1 8.6 11.1 18.8 6.8 9.4 9.2 17.8 18.3 12.9 9.4 10.6 7.4 8.0 8.5 11.3 8.7 7.4 13.7 7.1 33.0 9.6 10.1 8.7 9.1 9.7 9.2 3.7 9.5 16.7 10.7 10.3 20.5 18.8 15.3 11.7 2.7 1.7 1.1 2.1 1.4 1.4 1.3 1.9 1.7 1.2 2.2 1.9 2.4 1.8 1.7 1.4 1.9 1.6 1.3 3.2 3.6 5.3 4.9 2.5 3.7 3.0 3.1 3.1 1.5 3.7 5.1 20.5 12.8 23.5 7.8 14.7 16.4 22.4 14.0 15.4 31.8 10.6 8.0 11.5 10.0 19.9 12.9 39.6 21.8 14.5 11.6 5.9 18.6 1.6 13.9 17.8 16.6 8.4 15.3 13.4 17.9 13.4 15.7 10.7 14.4 18.3 17.3 9.3 12.7 10.7 37.0 14.3 15.7 18.3 7.3 9.1 1.9 14.6 10.2 8.8 9.4 18.4 23.2 17.5 9.5 13.2 19.3 8.0 15.8 19.0 24.1 9.1 15.2 28.8 34.7 6.6 28.6 14.7 15.5 15.7 11.8 18.8 24.4 16.7 19.4 18.3 23.2 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 242.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.5;Extravillous trophoblasts: 1015.1;Fibroblasts: 579.7;Syncytiotrophoblasts: 252.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 31.7" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 172.2;BJ: 63.7;EFO-21: 150.4;HeLa: 55.9;SuSa: 137.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 42.6" HPA010553 Enhanced "Secreted to extracellular matrix" NA NA 3200000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" 141.7 10.9 3.5 5.4 5.0 3.5 79.7 31.7 9.2 59.9 1.8 37.8 7.2 242.1 11.1 35.0 25.8 28.2 54.4 4.8 0.8 3.1 12.7 8.7 4.8 2.9 0.4 2.4 5.5 2.4 3.7 94.5 1.9 6.4 42.0 7.9 17.2 49.7 28.5 38.7 19.0 142.1 0.0 1.9 23.6 6.9 1.7 3.2 14.4 118.1 3.4 43.1 60.7 6.6 1.4 5.7 1.6 2.6 29.4 12.4 172.2 63.7 1.2 0.8 1.1 2.3 1.0 0.6 150.4 19.8 1.6 9.1 0.6 13.1 0.0 0.5 0.4 1.6 55.9 1.9 0.4 1.3 0.6 8.7 4.4 7.3 0.0 3.3 0.0 2.0 2.7 3.7 52.7 0.8 1.9 0.8 3.2 0.9 2.9 1.2 1.3 6.5 6.5 2.6 0.7 0.9 1.9 0.7 1.0 137.1 24.0 0.8 2.3 10.7 21.5 45.7 3.0 2.1 1.9 2.3 6.0 0.7 0.1 2.9 0.8 0.7 0.2 0.7 0.4 0.1 0.1 0.1 0.4 0.3 0.4 0.1 1.1 0.2 0.5 0.3 0.0 0.3 3.5 5.0 31.7 9.2 4.8 0.8 2.9 0.4 1.9 0.0 1.7 6.6 61.5 12.8 5.8 0.3 0.5 23.1 0.4 1.8 0.6 0.2 0.6 0.9 7.0 0.0 2.0 0.0 0.0 140.5 0.5 0.0 0.0 0.5 0.3 5.1 3.9 20.1 0.0 0.0 0.2 0.0 1015.1 579.7 3.6 28.0 0.0 0.2 4.2 0.0 27.7 0.0 0.1 0.0 0.0 9.5 36.3 0.5 61.2 8.8 12.4 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.6 0.1 0.0 0.2 1.6 0.9 0.0 40.2 35.2 0.1 0.2 0.6 18.0 252.3 5.3 0.1 0.0 0.3 MID1IP1 "FLJ10386, G12-like, MIG12, STRAIT11499, THRSPL" ENSG00000165175 "MID1 interacting protein 1" Q9NPA3 X 38801432-38806537 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 150.2" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 217.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038816 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA038816: AB_10670908" "unprognostic (5.35e-2)" "unprognostic (1.75e-1)" "unprognostic (1.24e-1)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.62e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-2)" "unprognostic (2.88e-1)" "unprognostic (2.31e-3)" "prognostic favorable (1.15e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-2)" "prognostic favorable (8.06e-4)" 40.2 34.1 102.1 13.9 143.4 103.6 34.5 106.6 105.3 20.4 50.4 45.0 17.0 18.3 6.9 35.5 30.9 7.5 39.5 78.6 91.9 29.5 56.1 43.7 11.1 115.4 123.4 33.4 78.7 4.0 15.4 8.7 107.4 23.0 5.0 3.4 25.0 13.3 150.2 28.7 25.1 9.3 99.2 12.3 49.7 23.0 127.8 9.1 13.8 25.9 6.2 35.5 24.3 139.5 60.3 55.2 14.3 10.9 67.9 31.8 15.4 33.2 23.2 7.1 13.5 18.5 44.3 57.7 28.4 10.7 6.0 55.3 47.7 39.4 4.7 39.9 18.7 49.4 48.7 14.9 51.6 23.1 36.7 46.4 31.1 27.7 24.2 19.1 7.2 68.9 46.5 60.7 10.1 50.4 40.8 64.3 49.5 17.6 95.9 111.2 17.6 116.4 18.5 29.8 34.0 41.3 17.6 34.0 90.9 28.2 28.0 70.5 10.0 20.2 22.4 25.5 24.6 155.5 65.0 53.6 61.1 37.4 22.3 3.8 1.9 15.7 0.9 1.3 1.0 0.5 1.4 1.0 1.3 0.7 1.2 1.2 8.0 0.8 2.0 1.3 0.5 0.9 102.1 143.4 106.6 105.3 78.6 91.9 115.4 123.4 107.4 99.2 127.8 139.5 20.3 80.1 217.9 11.4 17.4 23.7 48.5 63.0 44.3 12.5 22.4 21.1 40.5 52.9 28.2 20.2 4.2 3.7 16.6 23.3 37.2 36.7 8.3 65.6 25.0 25.3 25.8 54.1 1.7 70.0 20.2 57.7 49.5 20.8 48.8 13.2 24.3 40.5 40.4 15.2 2.7 33.2 63.1 53.2 73.8 12.7 39.4 60.5 26.6 5.6 130.4 20.7 8.2 3.5 47.6 67.0 24.4 49.7 6.9 36.7 18.1 47.9 48.0 12.4 39.5 42.7 52.8 2.4 3.7 63.0 16.3 4.9 35.4 16.3 25.5 116.9 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP27 ENSG00000137675 "Matrix metallopeptidase 27" Q9H306 11 102691487-102705769 "Enzymes, Predicted intracellular proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.7;salivary gland: 1.9;skin 1: 2.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Fibroblasts: 4.2;Langerhans cells: 1.8;Suprabasal keratinocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA069097 Approved "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 50: Fibroblasts - ECM organization" "HPA069097: AB_2686085" "unprognostic (3.99e-2)" "unprognostic (2.37e-4)" "unprognostic (1.25e-3)" "unprognostic (1.63e-1)" "unprognostic (4.60e-1)" 1.2 0.0 0.0 0.0 0.0 1.3 4.7 0.0 0.0 0.2 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.4 2.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;salivary gland: 286.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.4;Basal respiratory cells: 25.8;Early spermatids: 24.2;Extravillous trophoblasts: 13.4;Fibroblasts: 17.9;Prostatic glandular cells: 11.9;Smooth muscle cells: 10.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 4 "thalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BJ: 1545.7;BJ hTERT+: 4229.3;fHDF/TERT166: 1846.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 460000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 90.7 0.1 0.3 20.1 0.4 0.0 36.6 0.2 1.6 0.3 0.1 6.1 2.4 38.1 0.2 0.8 0.2 1.9 0.2 0.4 1.6 0.4 1.6 0.3 0.0 0.4 0.4 0.1 0.3 0.1 0.9 0.4 0.3 2.2 2.3 0.0 286.1 2.2 39.6 63.7 4.5 1.6 0.3 0.0 10.5 0.1 7.3 0.1 2.6 0.4 1.3 13.9 0.5 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1545.7 4229.3 27.0 8.7 0.1 0.2 0.0 0.0 1846.6 96.9 0.0 0.1 0.1 45.1 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 4.6 0.2 122.0 5.3 0.0 0.0 0.0 0.2 0.3 4.7 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.9 0.0 0.3 0.0 140.5 13.1 1.6 0.5 0.0 0.0 0.2 56.8 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.6 0.4 1.6 0.4 0.4 0.3 0.3 7.3 0.3 0.0 3.2 0.0 0.0 0.0 8.4 20.4 25.8 0.0 0.0 0.1 0.1 0.3 4.3 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.8 24.2 0.0 0.3 0.5 0.0 0.0 0.2 1.4 13.4 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.1 0.0 2.2 1.2 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 4.0 0.0 0.0 11.9 1.0 0.9 0.1 0.0 0.0 1.8 10.2 0.0 1.8 0.0 3.4 0.3 0.6 0.0 0.8 7.4 MN1 "MGCR, MGCR1, MGCR1-PEN" ENSG00000169184 "MN1 proto-oncogene, transcriptional regulator" Q10571 22 27748277-27801756 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.7;skeletal muscle: 61.6;tongue: 42.6" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Early spermatids: 22.3;Fibroblasts: 13.9;Langerhans cells: 11.2;Late spermatids: 15.2;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 30.7;HeLa: 12.7;hTERT-RPE1: 13.7;RH-30: 12.4;TIME: 20.1;U-2 OS: 16.3;U-2197: 17.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003072 Approved Approved Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003072: AB_1079399" "unprognostic (5.64e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-2)" "unprognostic (2.52e-2)" "unprognostic (7.01e-2)" "unprognostic (3.03e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (4.00e-2)" "unprognostic (7.33e-2)" "unprognostic (5.13e-7)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.28e-3)" "unprognostic (2.21e-4)" 4.1 0.8 6.0 1.6 20.7 1.3 2.3 6.4 9.5 2.2 0.5 6.1 0.8 2.7 1.0 3.6 4.3 3.0 6.7 1.9 5.3 0.9 0.4 3.3 0.1 4.3 13.0 9.6 0.7 0.1 2.7 1.3 6.8 2.3 0.9 1.8 2.7 1.2 61.6 1.8 2.1 2.5 2.1 0.4 4.0 0.8 8.5 0.3 2.1 42.6 0.7 3.3 3.5 3.1 0.0 1.5 30.7 0.9 0.6 1.3 0.0 0.7 1.1 0.0 0.0 0.0 0.1 0.0 3.1 5.7 1.3 2.7 1.5 1.8 0.0 0.0 0.8 0.0 12.7 0.0 0.7 0.0 0.3 0.1 3.5 0.7 3.0 13.7 0.3 0.0 0.0 0.2 1.0 0.0 0.0 0.4 4.0 0.0 2.8 5.3 12.4 0.0 0.4 0.0 0.1 0.4 2.7 0.0 0.0 7.5 0.3 0.1 20.1 1.0 16.3 17.9 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.0 20.7 6.4 9.5 1.9 5.3 4.3 13.0 6.8 2.1 8.5 3.1 2.1 3.2 2.3 12.1 0.3 4.2 0.1 2.6 3.4 8.4 1.8 0.6 7.4 1.5 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.4 22.3 1.4 1.0 6.6 0.0 0.0 6.4 1.0 0.1 13.9 0.5 3.1 0.0 0.6 2.5 0.6 0.3 0.0 9.6 0.0 2.0 1.4 11.2 15.2 5.0 2.7 0.0 2.8 0.3 3.9 0.0 13.0 4.3 2.8 0.0 10.1 1.3 0.2 0.0 0.1 0.1 0.7 0.0 2.4 2.3 0.4 1.1 1.9 2.7 0.0 0.3 0.4 0.0 0.2 MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 8.2" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041180: AB_10794266" "unprognostic (9.65e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.73e-1)" "unprognostic (4.38e-3)" "unprognostic (8.41e-2)" "unprognostic (8.99e-3)" "unprognostic (8.70e-2)" "unprognostic (6.36e-3)" "prognostic favorable (1.48e-11)" "unprognostic (2.84e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-3)" "unprognostic (3.87e-2)" 1.8 2.5 1.2 1.8 0.1 4.4 6.4 1.9 2.2 2.8 0.0 2.3 3.4 2.0 0.3 1.0 1.8 2.4 1.6 0.1 0.0 3.3 9.1 0.9 2.3 0.1 0.0 2.1 14.1 2.4 3.2 0.6 0.3 2.0 1.0 4.4 7.1 1.8 8.0 4.5 2.3 0.8 0.0 1.8 1.8 1.0 0.5 0.2 2.2 2.4 0.6 1.9 1.3 0.4 1.0 1.9 0.8 0.8 0.2 0.1 1.2 0.5 0.0 0.0 0.0 1.9 3.4 1.5 1.3 0.6 0.5 1.5 3.0 0.0 0.0 1.2 0.8 5.9 4.6 3.9 0.3 3.6 29.5 0.3 0.4 0.1 0.2 0.5 0.0 1.6 2.3 3.3 0.1 1.9 1.4 2.3 1.7 0.3 0.1 2.0 0.6 1.6 0.5 0.8 4.8 1.6 2.7 8.2 0.2 0.9 1.8 2.6 2.6 1.3 0.8 1.1 1.1 1.4 0.6 1.7 0.7 1.7 0.5 1.7 1.2 0.2 0.8 0.9 0.6 0.8 0.5 0.8 0.4 1.2 0.4 0.8 1.8 1.1 0.4 0.7 0.4 0.6 1.2 0.1 1.9 2.2 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.4 2.5 6.4 8.8 3.9 2.0 7.9 14.4 8.2 0.0 12.8 11.4 6.0 6.0 14.3 13.1 0.0 10.4 0.5 4.1 2.7 15.6 7.5 4.6 5.4 9.2 6.6 1.2 2.1 5.6 12.9 0.5 8.1 2.0 10.7 6.3 7.6 4.2 29.1 1.0 8.4 5.9 8.7 2.0 13.6 20.6 0.8 7.2 6.0 21.4 2.8 0.7 6.2 0.0 7.5 3.2 5.9 15.3 14.3 1.4 9.6 9.3 19.9 21.0 16.6 0.0 23.5 6.7 9.0 2.0 0.6 11.5 0.5 9.9 4.4 12.1 10.1 MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 183.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 183.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA026966: AB_10600931, HPA063538: AB_2685034" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.59e-2)" "unprognostic (4.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.27e-6)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.99e-7)" "unprognostic (3.55e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (4.21e-2)" 74.8 34.1 23.1 49.2 21.6 8.3 91.6 22.0 21.8 63.1 40.1 60.1 40.8 50.0 27.4 52.9 60.1 67.7 52.4 22.1 28.3 28.6 23.0 42.3 35.2 25.7 30.0 46.4 27.5 28.4 33.0 68.9 30.7 41.8 59.4 12.7 73.1 38.9 14.7 34.0 41.0 62.6 26.4 29.2 43.8 48.2 28.6 29.3 39.5 26.8 45.9 74.7 51.3 24.9 88.5 126.3 96.9 75.8 303.4 137.2 304.8 134.5 172.7 86.3 106.4 234.4 119.5 31.0 152.9 171.6 76.1 144.2 97.5 149.0 72.6 70.9 52.8 25.5 63.5 56.7 188.5 30.2 16.1 126.1 183.5 137.8 153.4 121.4 116.4 93.6 97.1 63.5 103.0 29.3 103.6 36.2 61.9 176.7 53.5 62.5 82.7 137.5 131.4 84.6 55.7 91.8 119.6 122.4 69.7 221.9 66.6 16.0 132.8 97.9 44.1 127.5 73.8 94.0 157.2 142.8 140.8 35.3 15.8 7.7 29.1 20.0 2.8 24.8 1.3 14.7 2.8 4.1 38.5 8.8 7.7 2.6 183.8 10.4 34.6 43.9 0.5 11.0 23.1 21.6 22.0 21.8 22.1 28.3 25.7 30.0 30.7 26.4 28.6 24.9 52.9 28.9 30.0 31.0 15.1 76.3 78.5 57.6 35.9 8.8 75.9 73.9 6.3 20.0 49.6 20.2 6.2 128.7 21.1 67.1 5.9 63.2 1.8 14.5 40.4 56.7 47.8 10.1 32.8 75.6 145.2 118.2 41.3 23.0 3.8 75.3 24.3 23.3 37.7 10.1 27.9 39.7 20.3 28.2 31.9 4.9 69.9 23.5 16.0 60.0 84.0 11.8 3.1 141.8 1.7 81.0 41.6 83.8 23.5 141.7 55.5 10.1 28.3 13.9 19.7 18.6 48.6 8.9 26.8 41.2 55.5 76.9 8.6 49.4 61.0 57.7 MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 93.9;Endometrial stromal cells: 65.2;Fibroblasts: 141.6;Late spermatids: 82.8;Leydig cells: 71.7;Peritubular cells: 102.3;Theca cells: 71.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 210.9;fHDF/TERT166: 164.9;HSkMC: 148.6;hTERT-RPE1: 150.6;U-138 MG: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" 24.5 8.6 4.8 13.7 7.9 5.3 16.2 5.6 5.3 39.3 22.5 12.3 6.6 31.3 9.6 21.2 26.3 32.4 45.2 4.3 5.1 18.1 2.8 35.0 4.5 9.3 9.1 45.8 7.5 1.2 17.4 9.6 8.9 25.7 3.2 0.7 9.0 20.8 12.2 28.8 10.9 21.3 9.9 16.3 9.0 16.2 6.0 4.5 7.0 6.5 2.0 17.9 28.2 11.2 0.1 35.1 23.3 29.7 64.1 115.4 3.1 210.9 138.8 34.3 40.8 2.1 0.4 0.0 15.2 164.9 15.1 17.8 4.0 19.0 8.8 26.7 5.4 17.6 27.2 0.0 97.2 22.9 0.2 148.6 9.5 29.6 3.4 150.6 15.4 10.6 9.3 0.0 47.8 6.3 6.6 70.6 4.9 0.0 2.4 22.3 15.4 0.2 3.2 0.4 2.9 52.2 14.1 0.4 0.3 14.3 0.6 97.1 68.5 216.6 83.9 36.2 43.6 0.2 0.0 0.0 66.8 22.6 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.8 7.9 5.6 5.3 4.3 5.1 9.3 9.1 8.9 9.9 6.0 11.2 8.6 3.2 35.9 5.9 0.4 11.3 5.8 20.7 25.0 11.1 1.6 11.4 4.4 0.0 2.3 1.8 0.0 0.7 0.6 0.1 0.0 0.3 93.9 22.6 65.2 5.2 0.0 28.4 3.3 0.2 2.7 141.6 2.0 2.9 2.5 13.8 5.3 0.0 6.8 0.0 0.9 0.1 0.0 9.2 11.1 82.8 71.7 7.0 5.4 57.1 0.6 0.8 1.0 3.5 0.9 0.6 0.0 102.3 0.3 2.1 0.0 0.0 1.4 0.6 0.0 31.4 23.3 11.7 9.3 34.6 7.7 1.9 2.7 71.0 0.2 1.4 MSTN GDF8 ENSG00000138379 Myostatin O14793 2 190055700-190062729 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 10.1;tongue: 15.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.7;Cone photoreceptor cells: 4.2;Early spermatids: 17.8;Late spermatids: 4.2;Muller glia cells: 19.1" "Cancer enriched" "Detected in some" 9 "glioma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "LHCN-M2: 25.9;RH-30: 52.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009963 Approved "Secreted in other tissues" NA NA 7600000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB009963: AB_2148798" "unprognostic (8.45e-2)" "unprognostic (2.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.54e-1)" "prognostic favorable (2.86e-4)" "unprognostic (7.59e-3)" "unprognostic (2.95e-1)" "unprognostic (4.09e-2)" "unprognostic (1.91e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-3)" "unprognostic (7.72e-3)" "unprognostic (1.12e-4)" "unprognostic (1.06e-1)" "unprognostic (3.94e-1)" "unprognostic (6.53e-2)" "unprognostic (5.67e-4)" 0.4 0.9 0.6 0.0 0.6 0.0 0.3 0.7 0.9 1.2 0.1 0.6 0.2 0.8 0.5 1.1 0.3 0.1 0.3 0.7 0.5 0.5 0.1 0.2 0.0 0.6 0.6 0.4 0.2 0.0 0.6 0.0 0.6 0.4 0.4 3.1 0.4 0.1 10.1 0.5 0.2 0.3 0.4 0.2 0.2 0.3 0.5 0.0 0.4 15.3 0.0 0.2 0.5 0.5 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.9 0.7 0.5 0.6 0.6 0.6 0.4 0.5 0.5 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 17.8 0.1 0.1 0.1 0.0 0.0 1.4 0.2 0.0 1.4 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.0 19.1 0.0 0.5 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 2.0 0.0 0.7 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MT1M "MT1, MT1K" ENSG00000205364 "Metallothionein 1M" Q8N339 16 56632659-56633981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 398.9;liver: 562.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1333.5;Distal enterocytes: 906.4;Glandular and luminal cells: 1180.5;Hepatocytes: 1549.5;Paneth cells: 1204.8;Proximal enterocytes: 933.2;Smooth muscle cells: 680.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 181.8" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.83e-2)" "unprognostic (2.49e-1)" "unprognostic (2.10e-2)" "unprognostic (3.10e-2)" "unprognostic (4.19e-3)" "unprognostic (7.73e-2)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.13e-4)" "unprognostic (4.67e-2)" "unprognostic (3.10e-1)" "unprognostic (3.55e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-2)" "unprognostic (4.71e-2)" 398.9 27.7 214.3 32.8 233.5 0.1 145.6 240.4 316.0 31.2 183.0 134.0 21.2 14.8 4.1 83.4 95.4 42.6 36.6 207.3 219.5 47.6 562.4 116.5 4.5 225.3 226.8 16.1 145.8 2.6 10.4 2.7 232.6 57.5 140.9 24.7 31.5 6.7 48.2 44.6 113.6 37.3 217.6 7.7 98.5 3.9 246.4 5.2 64.3 4.0 2.5 33.4 26.1 213.6 0.0 0.0 0.0 0.0 39.1 27.3 0.5 1.2 9.9 1.2 2.4 0.4 0.6 0.0 7.9 6.3 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.2 0.1 3.1 0.0 14.8 0.0 23.7 0.0 0.0 0.0 0.0 19.6 0.0 0.1 0.2 13.4 0.0 1.3 0.0 0.1 0.2 181.8 0.0 0.2 0.5 0.0 0.0 0.0 1.7 0.0 2.7 5.5 0.1 0.0 1.8 0.0 0.1 0.0 0.2 4.7 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 214.3 233.5 240.4 316.0 207.3 219.5 225.3 226.8 232.6 217.6 246.4 213.6 1333.5 12.8 7.2 49.6 9.3 27.5 19.0 3.1 27.9 0.0 13.7 52.7 7.9 121.5 6.0 14.7 0.0 0.3 4.9 906.4 37.2 58.9 0.1 413.6 114.7 141.3 32.7 131.0 0.1 117.0 70.5 308.1 25.5 1180.5 15.9 11.9 82.8 1549.5 1.7 0.0 0.1 397.5 0.0 65.9 39.9 1.5 47.8 35.2 88.9 5.6 24.3 0.0 0.0 6.0 0.3 64.1 1204.8 12.0 29.4 152.4 933.2 258.6 5.2 0.0 78.9 587.1 680.1 0.0 0.5 4.7 20.2 1.0 15.5 1.2 559.6 7.9 MUSK ENSG00000030304 "Muscle associated receptor tyrosine kinase" O15146 9 110668779-110806558 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Developmental protein, Kinase, Muscle protein, Receptor, Transferase, Tyrosine-protein kinase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.2;skeletal muscle: 4.1" "Cell type enhanced" "Detected in some" "Late spermatids: 4.8;Leydig cells: 5.3;Oligodendrocytes: 17.0;Peritubular cells: 19.5;Skeletal myocytes: 23.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "LHCN-M2: 24.7;RH-30: 23.7" "Region enhanced" "Detected in some" "basal ganglia: 5.0" "Not detected" "Not detected" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (6.12e-2)" "unprognostic (9.01e-2)" "unprognostic (5.39e-2)" "unprognostic (3.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.20e-2)" "unprognostic (1.50e-2)" "unprognostic (2.46e-1)" "unprognostic (3.13e-1)" "unprognostic (7.58e-2)" "unprognostic (6.03e-5)" "unprognostic (4.58e-2)" "unprognostic (1.62e-1)" "unprognostic (9.67e-2)" "unprognostic (5.11e-2)" 0.1 0.2 1.5 1.7 3.0 0.0 0.0 0.8 1.5 0.0 1.6 1.9 1.1 0.0 0.0 1.4 0.0 1.1 1.5 1.2 1.1 0.0 0.3 1.0 0.6 2.7 6.2 0.1 0.1 0.0 0.0 0.3 1.7 0.2 2.5 0.0 0.1 0.0 4.1 0.1 2.4 0.5 2.9 0.0 1.3 1.6 2.0 0.1 0.0 2.0 2.0 1.2 0.0 4.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.5 0.0 0.2 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 3.0 0.8 1.5 1.2 1.1 2.7 6.2 1.7 2.9 2.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.3 0.1 0.0 0.0 1.3 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 4.8 5.3 0.0 0.0 1.9 0.0 0.0 0.0 2.5 17.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.1 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 149.5;Extravillous trophoblasts: 259.9;Fibroblasts: 183.3;Leydig cells: 176.1;Peritubular cells: 183.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.0;BJ: 143.6;BJ hTERT+: 66.9;fHDF/TERT166: 71.9;HSkMC: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" 103.6 11.7 2.9 8.2 2.5 0.6 70.0 1.1 2.9 100.4 1.7 58.2 6.3 117.2 2.6 17.6 57.4 19.4 42.8 4.0 2.4 26.4 7.4 53.9 2.5 5.9 4.5 81.9 8.7 1.1 21.7 11.6 2.6 39.0 1.7 0.8 32.4 11.4 16.6 41.6 29.5 6.4 2.3 26.4 28.9 14.7 3.2 0.6 46.6 5.0 0.8 52.8 59.3 3.0 4.1 0.8 1.2 1.0 16.5 46.0 42.3 143.6 66.9 16.6 19.9 8.0 3.3 1.7 0.6 71.9 0.1 3.0 1.0 0.0 3.2 3.2 1.3 1.2 3.1 12.8 43.4 0.2 1.6 54.8 0.0 6.2 0.0 32.4 0.0 0.9 17.3 1.4 21.5 0.4 0.4 0.5 14.0 0.3 4.7 0.6 0.3 0.4 0.0 0.7 3.2 8.9 0.5 1.4 0.1 10.4 11.1 0.7 1.3 0.7 23.1 21.8 0.6 3.3 0.3 0.2 5.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.2 2.9 2.5 1.1 2.9 4.0 2.4 5.9 4.5 2.6 2.3 3.2 3.0 22.2 3.2 0.0 7.5 0.5 10.7 1.1 0.7 2.2 0.7 7.0 47.9 3.5 0.0 0.0 9.2 0.0 9.5 1.1 0.0 0.0 5.7 1.7 4.3 149.5 5.1 0.0 0.0 0.3 0.0 259.9 183.3 2.6 3.7 0.0 0.5 6.4 0.1 9.3 0.0 0.4 0.0 0.0 0.0 19.7 11.4 176.1 1.7 10.6 6.5 0.7 50.7 0.0 0.0 0.1 1.1 0.0 183.6 1.4 0.6 0.0 1.4 0.0 1.5 13.1 65.8 74.7 0.7 5.4 1.3 10.5 29.4 2.2 0.8 0.0 0.3 MYF5 bHLHc2 ENSG00000111049 "Myogenic factor 5" P13349 12 80716912-80719671 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 5.6;tongue: 8.9" "Cell type enriched" "Detected in single" 1159 "Skeletal myocytes: 347.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "LHCN-M2: 478.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA041691 Supported Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA041691: AB_10796780" "unprognostic (2.65e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 478.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 347.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 MYOC "GLC1A, JOAG1, TIGR" ENSG00000034971 Myocilin Q99972 1 171635417-171652688 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 110.8" "Cell type enriched" "Detected in some" 6 "Fibroblasts: 244.4" "Cancer enriched" "Detected in many" 6 "melanoma: 13.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA027364 Uncertain "Secreted to extracellular matrix" NA NA 25000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "HPA027364: AB_10602036" "unprognostic (2.02e-2)" "unprognostic (4.65e-2)" "unprognostic (4.44e-2)" "unprognostic (6.29e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-2)" "unprognostic (3.42e-2)" "unprognostic (3.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.94e-4)" "unprognostic (5.35e-2)" "unprognostic (1.87e-1)" "unprognostic (3.87e-2)" "unprognostic (1.24e-1)" 47.1 1.1 0.0 0.0 0.0 0.0 19.2 0.2 0.0 1.8 0.0 13.0 3.5 16.5 4.9 19.6 15.3 1.5 18.3 0.0 0.1 0.2 0.1 7.4 0.1 0.5 0.1 1.3 3.0 0.1 0.2 0.2 0.2 5.3 3.5 0.0 14.0 6.4 33.8 4.7 4.8 2.9 0.0 0.0 50.2 1.4 0.1 14.1 28.7 110.8 0.2 22.6 9.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.1 0.2 0.0 0.1 0.1 12.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.1 3.1 0.0 0.0 0.1 0.0 0.0 244.4 11.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.1 1.0 8.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.6 2.4 0.1 0.0 0.0 0.0 0.0 0.0 15.1 6.3 0.1 0.1 1.1 0.0 0.0 1.1 0.2 0.0 0.0 NFIA "KIAA1439, NFI-L" ENSG00000162599 "Nuclear factor I A" Q12857 1 60865259-61462788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.9" "Cell type enhanced" "Detected in all" "Astrocytes: 777.3;Oligodendrocyte precursor cells: 606.7;Peritubular cells: 438.5;Skeletal myocytes: 513.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006111, HPA008884" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA006111: AB_1854422, HPA008884: AB_1854421" "unprognostic (1.50e-3)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" "unprognostic (3.44e-2)" "prognostic favorable (7.30e-4)" "unprognostic (2.55e-1)" "unprognostic (1.22e-2)" "unprognostic (9.12e-2)" "unprognostic (9.38e-2)" "unprognostic (2.85e-2)" "unprognostic (5.20e-2)" "prognostic favorable (7.01e-4)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.03e-4)" 23.0 12.4 28.4 5.2 37.7 10.0 15.1 75.9 24.6 18.3 31.8 14.2 7.2 8.9 11.7 18.8 15.6 14.3 16.9 28.4 31.3 10.8 40.5 8.4 5.1 51.5 33.4 15.7 13.5 10.9 5.4 4.3 34.9 15.0 9.1 4.2 17.5 11.6 13.8 8.7 6.4 13.2 37.3 9.4 9.7 5.8 33.6 8.6 27.4 15.8 6.8 13.8 10.3 27.1 5.0 6.8 1.0 74.2 31.8 20.2 0.2 1.6 5.1 1.6 2.4 0.4 4.8 10.9 4.8 2.7 0.7 7.2 3.1 15.4 0.9 23.4 6.6 0.4 15.2 4.8 7.3 1.2 1.8 25.7 14.9 6.8 27.6 5.5 19.1 3.0 5.1 16.9 1.5 3.6 0.3 0.3 2.9 6.9 6.6 1.1 6.9 18.2 4.3 13.1 4.8 5.7 4.1 28.2 10.3 0.8 30.2 0.5 15.5 1.3 8.5 15.2 3.1 1.2 3.1 0.1 1.7 0.2 1.7 3.2 2.7 1.5 1.9 1.9 2.9 0.6 2.3 3.0 1.3 0.3 2.2 2.7 0.1 0.5 2.5 1.0 0.1 1.8 28.4 37.7 75.9 24.6 28.4 31.3 51.5 33.4 34.9 37.3 33.6 27.1 232.1 35.3 44.7 777.3 4.4 85.0 68.8 72.1 220.9 42.6 140.7 107.4 192.9 148.7 68.1 47.8 2.1 5.7 8.1 28.4 27.4 38.0 28.9 85.8 69.8 132.7 25.2 163.7 142.3 47.8 1.1 265.6 30.5 68.2 27.3 11.6 197.0 304.5 14.8 42.1 125.7 46.8 36.7 60.8 42.6 26.4 408.8 19.2 46.2 259.5 14.9 150.2 5.2 606.7 431.3 20.8 37.6 438.5 8.0 53.0 19.1 109.9 82.6 6.9 144.7 513.1 133.7 5.0 13.5 148.4 76.3 1.6 15.0 34.9 69.7 57.1 NFIX NF1A ENSG00000008441 "Nuclear factor I X" Q14938 19 12995475-13098796 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 410.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.2;Oligodendrocytes: 140.9;Skeletal myocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 149.5;fHDF/TERT166: 211.3;U-138 MG: 191.5;U-2197: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007533 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA007533: AB_2667855" "unprognostic (3.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.84e-1)" "unprognostic (2.20e-1)" "unprognostic (2.29e-1)" "unprognostic (8.12e-2)" "prognostic favorable (4.66e-4)" "prognostic favorable (2.35e-4)" "unprognostic (1.26e-1)" "unprognostic (2.01e-2)" "unprognostic (3.25e-1)" "unprognostic (2.63e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.92e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-2)" 76.4 14.9 30.4 19.7 80.2 14.9 48.0 99.8 97.7 67.2 4.0 60.4 20.9 88.5 10.9 72.4 69.5 53.9 60.9 54.0 15.0 8.9 20.3 50.0 6.2 50.9 45.1 73.8 23.8 13.2 18.9 11.8 39.4 85.0 19.7 11.7 150.4 60.0 410.3 99.2 24.3 67.8 45.6 11.3 37.3 16.0 46.9 11.6 31.0 138.2 6.2 45.0 52.7 105.2 39.2 16.2 1.0 119.9 111.7 149.5 1.3 48.1 68.6 45.7 31.8 1.3 3.3 0.6 13.4 211.3 31.4 17.5 12.8 37.4 20.1 25.8 19.7 20.2 7.6 17.2 53.8 8.5 10.3 99.0 10.9 44.1 24.6 80.3 12.4 8.6 6.7 6.2 29.3 12.1 14.9 5.7 0.5 8.6 132.3 43.5 22.2 23.1 0.4 8.5 17.9 47.6 34.5 0.3 43.0 0.0 22.7 17.3 12.2 191.5 23.5 185.1 68.5 4.5 1.7 0.3 49.9 12.1 62.0 0.1 0.1 0.0 0.5 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 30.4 80.2 99.8 97.7 54.0 15.0 50.9 45.1 39.4 45.6 46.9 105.2 19.5 12.8 59.3 62.7 6.8 58.8 45.5 22.4 134.9 13.3 57.9 74.2 33.2 27.1 15.9 14.7 4.2 0.2 3.7 16.5 1.9 24.3 64.0 12.1 40.1 20.0 12.1 145.2 69.0 12.7 0.3 89.7 32.6 3.0 3.8 4.3 17.9 33.9 1.0 0.0 38.1 25.8 2.0 4.1 15.2 43.1 112.2 5.8 26.6 17.8 1.9 93.7 0.0 52.3 140.9 15.2 12.0 126.0 2.5 60.3 8.4 10.0 19.0 3.0 6.6 174.7 38.3 15.6 13.2 99.4 51.4 0.3 3.8 56.0 29.5 31.8 NOVA1 NOVA-1 ENSG00000139910 "NOVA alternative splicing regulator 1" P51513 14 26443090-26598033 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 222.9;Excitatory neurons: 414.9;Oligodendrocyte precursor cells: 1269.7;Oligodendrocytes: 319.5" "Cancer enriched" "Detected in many" 5 "glioma: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.3;ASC diff: 25.6;HAP1: 23.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004155 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA004155: AB_1079497" "unprognostic (1.46e-1)" "unprognostic (4.43e-3)" "unprognostic (6.55e-3)" "unprognostic (4.00e-2)" "unprognostic (6.69e-3)" "unprognostic (4.29e-2)" "unprognostic (3.74e-3)" "unprognostic (2.41e-1)" "unprognostic (5.21e-1)" "unprognostic (4.32e-2)" "unprognostic (5.04e-4)" "unprognostic (2.40e-1)" "unprognostic (1.93e-3)" "unprognostic (9.27e-4)" "unprognostic (9.20e-2)" "unprognostic (5.62e-2)" "unprognostic (1.31e-4)" 23.4 5.4 44.0 2.4 39.7 0.1 28.9 85.4 56.3 12.1 18.9 11.6 1.4 8.5 4.9 2.9 6.7 4.8 3.3 38.8 65.3 6.1 0.9 1.4 3.4 50.3 51.2 5.0 1.2 2.4 19.3 0.1 48.5 5.6 5.1 13.4 2.7 15.9 4.3 4.7 3.6 9.5 49.2 0.9 3.3 8.8 71.1 1.2 3.4 8.7 4.5 5.9 8.4 45.5 0.0 11.6 53.3 0.0 25.6 14.6 0.1 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.7 0.7 7.1 0.1 23.7 0.2 0.0 0.0 1.8 0.0 0.1 0.3 8.5 0.0 2.1 16.8 0.0 3.6 2.9 17.8 10.3 8.7 0.0 0.1 8.4 0.0 9.8 0.1 13.5 0.0 10.9 1.3 14.8 0.2 6.8 9.1 15.5 9.4 0.0 0.0 0.0 4.2 1.1 0.0 0.0 6.5 7.7 5.2 1.4 0.0 0.0 0.0 8.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 44.0 39.7 85.4 56.3 38.8 65.3 50.3 51.2 48.5 49.2 71.1 45.5 24.8 0.0 1.5 141.0 0.2 5.2 5.9 0.0 4.6 222.9 51.5 29.6 1.1 5.7 0.0 14.7 4.2 0.1 1.4 6.6 9.8 0.4 20.1 0.6 15.0 9.4 65.9 0.0 414.9 0.4 0.0 188.8 0.5 0.2 0.0 18.2 38.6 0.5 0.2 136.3 203.5 7.1 0.0 0.6 10.5 16.5 150.4 2.1 3.6 93.7 0.0 32.3 0.0 1269.7 319.5 2.0 11.7 65.8 1.9 6.7 0.3 30.3 4.4 12.0 6.6 28.6 17.7 163.1 64.3 0.7 3.1 0.0 1.5 30.0 8.4 0.6 NPIPA9 ENSG00000233024 "Nuclear pore complex interacting protein family, member A9" 16 18358086-18379331 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" HPA053611 Approved Uncertain Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (9.10e-2)" "unprognostic (6.00e-3)" "unprognostic (1.66e-1)" "unprognostic (5.77e-2)" "unprognostic (8.31e-2)" "unprognostic (6.34e-2)" "unprognostic (6.34e-2)" "unprognostic (6.76e-2)" "unprognostic (1.30e-3)" "unprognostic (5.87e-2)" "unprognostic (5.79e-3)" "unprognostic (1.60e-2)" "unprognostic (1.25e-5)" "unprognostic (1.96e-1)" "unprognostic (1.90e-2)" "unprognostic (5.38e-2)" "unprognostic (6.45e-3)" 67.7 62.8 166.9 26.7 164.4 29.4 66.5 232.7 283.1 82.8 136.2 119.7 25.7 74.7 58.4 63.5 78.1 30.6 77.6 168.1 177.5 79.6 64.1 67.1 32.4 165.7 150.8 135.0 75.1 44.7 224.4 22.8 169.8 89.4 40.2 72.4 55.9 43.0 115.1 73.9 69.2 47.7 132.7 74.7 64.7 84.8 152.5 30.7 81.4 29.1 27.3 70.2 66.3 162.9 23.6 15.1 82.7 67.9 69.4 64.4 19.3 88.5 32.1 42.6 63.0 15.2 13.6 32.6 33.2 78.4 25.2 41.7 26.0 24.0 51.9 27.8 24.8 87.0 85.7 75.4 70.3 41.7 190.6 66.6 105.3 53.5 71.4 89.2 21.1 39.3 20.4 62.7 43.1 35.8 68.2 89.3 34.8 23.2 19.0 97.1 20.6 32.5 42.4 43.9 23.4 36.2 55.5 34.5 49.3 31.6 31.9 48.4 40.4 56.9 24.9 48.4 27.5 46.9 40.3 49.2 25.5 56.2 30.1 0.0 0.1 0.1 0.5 0.0 0.2 1.4 0.4 0.3 0.0 0.3 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 166.9 164.4 232.7 283.1 168.1 177.5 165.7 150.8 169.8 132.7 152.5 162.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPIPB3 "KIAA0220, NPIPL3" ENSG00000169246 "Nuclear pore complex interacting protein family member B3" Q92617 16 21402237-21448567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.8;Gastric mucus-secreting cells: 2.0;Skeletal myocytes: 3.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 161.9" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (2.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "unprognostic (8.01e-2)" "unprognostic (9.97e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-2)" "unprognostic (3.14e-1)" "unprognostic (3.91e-1)" "unprognostic (1.65e-1)" "unprognostic (4.66e-5)" "unprognostic (1.50e-7)" "unprognostic (1.30e-1)" "unprognostic (3.02e-2)" "unprognostic (5.94e-2)" "unprognostic (9.00e-4)" 53.3 47.1 141.3 37.2 137.3 149.4 47.7 127.7 184.3 71.8 111.9 72.4 28.5 38.3 51.8 44.4 58.6 28.5 60.8 118.8 134.1 71.1 65.1 66.3 77.0 133.3 147.3 49.6 47.2 13.1 70.5 21.9 127.9 74.9 34.9 51.7 43.5 22.6 87.9 140.9 76.7 28.1 90.1 99.7 51.3 46.6 134.8 53.6 75.6 24.1 34.8 48.0 52.5 122.8 37.9 37.2 24.5 40.1 30.0 18.1 73.5 25.7 9.6 13.3 14.1 57.5 44.0 56.4 24.1 38.9 17.7 47.0 13.6 41.4 12.5 30.8 20.6 26.6 58.7 161.9 25.6 48.8 46.0 8.8 16.8 35.3 44.3 20.4 19.4 52.5 49.7 77.3 20.4 69.7 51.8 114.0 41.0 22.5 42.5 75.7 25.4 35.0 28.8 23.2 27.8 21.1 15.7 32.5 25.9 47.2 35.7 20.7 29.5 62.9 36.4 6.4 40.4 37.8 30.8 49.2 25.0 38.3 34.9 3.5 2.3 1.5 2.6 1.4 1.2 2.2 1.5 1.6 1.2 2.4 2.0 1.3 2.1 2.0 1.1 4.8 0.9 0.1 141.3 137.3 127.7 184.3 118.8 134.1 133.3 147.3 127.9 90.1 134.8 122.8 0.1 0.0 0.0 1.6 0.5 2.8 0.4 0.2 0.6 0.0 0.1 0.0 1.1 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.7 0.0 0.0 1.7 0.0 0.0 1.0 2.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.3 0.6 0.0 0.0 0.2 1.8 1.9 0.0 0.0 1.0 1.5 1.3 0.0 0.0 0.0 0.7 0.8 0.0 0.0 1.7 0.0 0.0 3.1 0.8 0.0 0.0 1.3 1.7 0.0 0.8 0.2 0.0 0.2 NPPC CNP ENSG00000163273 "Natriuretic peptide C" P23582 2 231921809-231926396 "Predicted secreted proteins, Transporters" Osteogenesis "Hormone, Vasoactive" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 33.5" "Group enriched" "Detected in many" 8 "Basal squamous epithelial cells: 190.1;Skeletal myocytes: 264.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "medulla oblongata: 33.5;spinal cord: 30.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;NTERA-2: 3.9;SCLC-21H: 5.5;SK-MEL-30: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.5;spinal cord: 12.5" HPA035362 Uncertain "Secreted to blood" NA NA 6140 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA035362: AB_10671103" "unprognostic (9.70e-2)" "unprognostic (4.45e-2)" "unprognostic (1.99e-1)" "unprognostic (1.06e-2)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-3)" "unprognostic (9.81e-3)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" "unprognostic (4.06e-2)" "unprognostic (1.17e-1)" "unprognostic (6.58e-2)" "unprognostic (1.18e-1)" "unprognostic (3.72e-1)" "unprognostic (1.91e-1)" 0.3 0.1 0.8 2.1 0.9 1.3 0.7 2.8 3.4 1.3 0.0 4.1 0.1 0.6 0.0 3.2 2.6 0.0 5.3 2.0 3.9 0.2 0.0 0.0 1.4 33.5 4.4 1.3 0.1 0.0 2.7 0.2 4.8 4.3 0.2 2.4 1.1 0.4 0.7 0.6 0.9 0.5 30.9 0.4 2.4 0.2 4.6 2.9 0.5 0.1 2.0 0.2 0.4 6.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 1.0 0.0 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.5 0.3 0.2 0.2 26.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 2.8 3.4 2.0 3.9 33.5 4.4 4.8 30.9 4.6 6.5 2.1 0.0 0.0 0.7 1.3 3.4 27.1 5.9 190.1 1.1 6.5 18.3 1.9 0.0 0.1 11.0 10.4 0.2 0.6 4.2 0.0 1.1 0.3 3.6 1.3 1.6 3.5 0.0 0.0 0.0 0.0 10.9 5.6 4.8 0.0 0.3 0.0 0.0 0.1 0.0 1.5 3.2 0.0 0.0 1.7 0.0 0.3 1.6 1.8 0.0 2.5 15.2 0.0 0.0 1.3 0.8 3.1 0.0 5.8 11.5 0.0 0.0 0.0 4.1 0.0 264.2 2.0 1.2 7.0 13.2 1.1 0.3 1.7 0.0 2.9 3.1 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 58.0;Oligodendrocyte precursor cells: 61.3;Pancreatic endocrine cells: 124.8;Rod photoreceptor cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 807.8;LHCN-M2: 934.3;TIME: 546.2;U-87 MG: 821.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 20.7 6.0 9.8 11.9 11.9 0.6 14.1 11.2 10.7 112.6 14.9 29.4 40.1 49.4 6.3 8.6 20.7 17.2 8.7 8.5 11.3 17.2 54.8 6.8 9.6 11.7 14.1 39.3 1.8 1.8 11.8 25.3 13.0 13.3 31.9 94.4 6.6 34.2 2.1 6.4 20.9 73.9 14.7 13.0 8.1 10.4 12.7 5.2 23.7 9.8 11.3 15.8 28.5 12.1 48.9 26.0 42.9 0.8 95.1 302.4 0.4 306.1 332.7 147.5 275.2 0.4 469.6 0.0 107.3 270.2 379.0 24.5 0.1 308.0 348.8 0.8 0.1 0.1 7.3 6.0 47.5 0.2 0.7 77.4 3.7 302.0 191.3 807.8 124.9 0.3 0.3 1.4 934.3 8.3 0.0 0.2 0.8 8.2 34.6 1.5 9.5 1.3 323.1 21.8 0.3 5.5 3.8 18.8 104.9 2.2 0.4 8.3 546.2 120.6 0.9 152.9 506.8 22.7 15.3 0.5 821.7 0.4 385.3 0.0 0.0 0.5 3.7 0.0 6.4 23.7 4.2 11.7 0.0 33.0 4.1 30.7 0.5 0.7 0.0 0.1 1.7 6.4 9.8 11.9 11.2 10.7 8.5 11.3 11.7 14.1 13.0 14.7 12.7 12.1 6.4 0.0 5.8 36.9 21.6 5.2 1.7 6.1 2.8 4.4 1.2 0.3 1.7 27.1 4.8 1.8 10.4 0.6 2.2 49.2 3.9 3.8 0.6 19.3 20.8 20.5 0.0 0.0 1.6 4.1 2.5 39.4 11.2 58.0 0.0 0.1 49.6 33.7 1.3 0.0 2.1 27.7 0.0 3.5 8.2 1.3 13.1 2.1 7.2 11.2 0.5 9.1 0.0 61.3 0.7 124.8 46.0 25.6 3.6 1.5 8.3 27.6 4.8 81.6 0.0 3.3 9.6 0.0 0.3 0.6 4.8 15.2 5.0 0.1 18.0 9.6 NUMBL "CAG3A, CTG3a, NUMB-R, NUMBLIKE, NUMBR, TNRC23" ENSG00000105245 "NUMB like endocytic adaptor protein" Q9Y6R0 19 40665905-40690972 "Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 42.6;Peritubular cells: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058251, HPA058380" Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "HPA058251: AB_2683653, HPA058380: AB_2683698" "unprognostic (2.78e-2)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.49e-4)" "unprognostic (1.78e-2)" "unprognostic (1.27e-1)" "unprognostic (7.29e-2)" "unprognostic (7.14e-3)" "unprognostic (7.50e-2)" "unprognostic (3.22e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (1.56e-1)" "unprognostic (3.91e-2)" "prognostic unfavorable (7.55e-15)" "unprognostic (1.91e-2)" "unprognostic (2.83e-2)" "unprognostic (8.27e-2)" "unprognostic (1.69e-3)" 31.3 16.2 25.0 8.1 27.7 3.0 22.2 19.1 31.2 49.3 0.1 35.2 8.4 45.2 6.2 17.6 46.6 11.4 25.9 31.3 18.5 12.4 15.4 25.6 3.9 6.3 11.9 38.8 10.1 2.4 72.4 5.7 10.6 35.2 3.8 5.2 14.7 13.9 11.4 17.9 18.2 12.5 3.9 12.6 22.2 25.3 17.4 2.3 28.4 6.1 2.6 36.2 38.0 13.9 17.0 46.4 9.7 25.7 22.8 22.4 5.4 20.2 17.5 11.7 14.1 17.5 12.4 6.2 19.7 29.4 8.8 16.4 7.1 8.8 6.2 16.8 11.8 6.8 47.0 2.4 24.2 3.4 7.7 21.5 5.9 19.2 8.1 18.2 16.7 5.4 20.0 7.1 8.2 15.5 10.8 3.3 11.3 9.9 10.7 9.1 26.5 12.7 3.4 4.7 19.3 34.1 22.2 12.9 19.7 6.1 13.1 5.7 31.9 21.2 24.1 33.7 25.6 9.3 11.9 3.9 34.1 10.8 12.3 0.0 0.1 0.0 1.1 0.0 0.1 0.1 0.1 0.3 0.0 0.2 0.1 0.4 0.2 0.0 0.8 0.2 0.0 0.2 25.0 27.7 19.1 31.2 31.3 18.5 6.3 11.9 10.6 3.9 17.4 13.9 6.9 0.0 3.4 13.4 2.7 13.6 14.6 2.4 4.6 14.2 4.9 6.1 4.0 4.3 3.4 0.0 0.0 2.8 4.1 1.8 0.0 2.5 24.7 10.4 24.7 6.0 7.2 1.7 12.9 1.8 5.4 24.2 6.6 7.9 0.0 5.5 5.7 2.2 1.6 11.8 7.4 3.5 0.0 1.9 6.8 10.1 42.6 2.3 3.6 3.7 0.5 3.0 0.0 9.0 4.9 1.7 3.3 51.6 1.4 18.7 2.5 0.6 9.2 4.6 0.0 20.6 10.4 1.4 3.3 5.6 21.0 2.2 2.3 6.9 3.3 8.8 NXPH3 NPH3 ENSG00000182575 "Neurexophilin 3" O95157 17 49575871-49583827 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Bipolar cells: 23.3;Fibroblasts: 7.6;Muller glia cells: 8.5;Peritubular cells: 14.3;Smooth muscle cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 11.4;BJ: 3.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 41.1" HPA073819 Approved "Vesicles,Mitotic spindle" "Secreted in brain" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Mitotic spindle" "HPA073819: " "unprognostic (2.39e-2)" "unprognostic (4.75e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-1)" "unprognostic (1.92e-1)" "unprognostic (3.30e-1)" "unprognostic (1.97e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-2)" "unprognostic (6.33e-2)" "unprognostic (4.62e-4)" "unprognostic (2.59e-2)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (5.05e-3)" 3.9 0.9 1.8 1.0 1.8 0.0 2.9 16.4 3.5 9.0 0.7 11.0 0.4 12.0 0.6 1.5 7.0 1.7 2.9 3.5 0.5 0.4 0.1 2.7 0.5 6.3 3.8 5.2 0.6 1.3 7.5 1.3 6.4 5.9 0.3 0.6 3.1 4.7 1.2 2.3 1.7 2.5 0.1 1.0 3.4 1.6 3.9 0.3 1.4 2.0 0.3 8.9 6.9 3.0 0.0 0.0 0.1 0.0 0.0 0.2 11.4 3.2 0.4 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 16.4 3.5 3.5 0.5 6.3 3.8 6.4 0.1 3.9 3.0 0.5 0.0 1.3 14.0 0.0 0.4 0.3 0.2 0.6 23.3 0.9 0.5 1.7 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.6 0.0 0.0 2.5 0.2 3.2 7.6 0.0 0.5 0.0 0.0 6.4 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.4 0.0 4.4 0.3 1.8 0.0 4.2 8.5 0.0 2.5 0.5 0.0 0.0 14.3 0.7 0.3 0.0 0.0 0.0 1.2 0.0 0.8 8.9 0.1 1.3 0.0 1.1 0.1 0.2 0.1 0.0 0.1 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.9;Fibroblasts: 135.9;Hepatocytes: 218.8;Muller glia cells: 279.4;Theca cells: 149.0;Urothelial cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 115.5;Hep G2: 190.1;NB-4: 139.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" 66.0 91.5 47.7 18.0 56.8 10.8 42.6 35.8 57.1 66.7 40.5 61.9 47.7 54.2 16.0 22.8 54.6 34.5 55.1 48.1 36.5 51.4 396.6 19.2 5.8 39.0 37.8 61.0 74.1 6.7 27.4 8.1 37.1 33.5 36.5 30.7 53.9 13.7 13.2 12.0 57.3 29.1 35.9 54.4 33.5 3.7 45.0 4.6 25.9 12.2 3.7 42.6 40.4 44.6 24.9 7.5 30.9 14.4 47.8 53.4 1.7 47.7 53.8 20.5 30.0 7.5 37.3 0.0 115.5 35.6 33.7 25.7 8.9 13.2 8.2 18.7 21.1 21.1 4.7 190.1 42.4 46.7 7.9 66.8 7.9 19.8 54.8 39.9 59.7 12.7 14.0 22.7 5.0 9.4 0.3 139.9 11.6 7.3 40.8 11.8 0.9 23.7 31.8 13.4 1.5 10.0 14.0 15.2 40.2 8.6 4.8 74.7 32.7 39.3 14.7 40.8 4.6 0.8 0.7 0.4 30.3 76.2 14.1 0.0 3.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.1 0.0 0.3 0.5 0.1 0.8 47.7 56.8 35.8 57.1 48.1 36.5 39.0 37.8 37.1 35.9 45.0 44.6 19.4 0.0 0.6 102.2 3.7 9.4 33.6 7.3 12.5 3.2 6.0 7.0 5.5 34.3 3.5 71.7 2.1 2.1 1.1 135.9 27.4 14.8 0.2 4.7 70.9 40.0 22.8 12.8 0.6 28.7 5.5 135.9 11.7 12.2 1.3 2.6 12.5 218.8 6.0 0.0 2.3 56.5 4.1 11.5 20.9 1.1 16.8 11.0 16.0 23.4 10.2 279.4 0.0 5.5 11.0 28.2 56.5 4.5 14.5 31.3 111.1 79.3 0.4 10.6 52.6 8.6 40.8 0.7 6.9 11.3 10.2 6.2 3.1 149.0 45.8 192.5 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.3" "Cell type enhanced" "Detected in many" "Early spermatids: 122.5;Hofbauer cells: 38.4;Skeletal myocytes: 175.5;Smooth muscle cells: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.7;HSkMC: 113.3;RH-30: 88.5" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA054136: AB_2682397, HPA062739: AB_2684858" "unprognostic (2.97e-2)" "unprognostic (1.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (5.97e-3)" "unprognostic (7.32e-2)" "unprognostic (7.68e-3)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.01e-12)" "unprognostic (1.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.53e-3)" "unprognostic (1.97e-2)" 23.4 6.9 4.2 19.2 7.5 0.4 14.7 2.4 5.6 16.8 6.0 18.3 2.1 16.2 5.0 3.9 11.4 48.3 6.6 5.7 3.4 3.1 0.8 15.3 14.0 3.7 4.0 4.2 1.4 3.5 2.8 40.6 4.7 5.3 2.9 0.2 10.4 6.9 10.2 10.1 5.5 22.0 3.0 10.2 3.3 15.9 9.8 3.7 20.8 6.5 11.2 16.8 7.3 4.2 0.1 0.4 6.6 2.2 21.0 39.7 0.0 2.3 10.6 4.3 11.8 0.0 0.2 0.0 0.3 25.7 4.3 0.0 0.6 0.1 2.5 0.0 0.8 0.5 0.2 0.0 0.3 0.1 0.8 113.3 0.0 5.3 0.0 2.1 0.7 0.0 0.0 1.0 19.3 0.1 0.1 0.2 2.1 0.0 1.0 0.2 88.5 8.9 1.6 0.1 0.8 0.3 9.1 0.0 0.6 19.6 0.0 0.1 0.1 2.7 0.7 4.0 3.6 0.0 0.1 0.0 25.1 2.7 1.3 0.0 0.4 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.2 4.2 7.5 2.4 5.6 5.7 3.4 3.7 4.0 4.7 3.0 9.8 4.2 4.1 0.0 0.6 0.0 0.2 3.3 0.1 0.1 0.0 0.1 0.4 1.0 3.0 1.5 0.7 1.8 0.0 0.3 0.1 0.0 0.0 0.0 122.5 1.2 24.9 1.7 0.0 0.4 2.8 0.0 0.3 21.9 0.0 0.7 1.3 1.1 1.1 0.2 38.4 0.0 0.9 0.1 0.0 31.1 9.0 12.9 20.8 16.6 1.8 8.4 0.9 0.8 0.0 0.0 2.9 0.0 0.0 29.3 0.1 0.1 0.0 0.1 0.1 0.1 6.6 175.5 57.2 8.8 1.7 0.1 2.3 0.3 0.6 16.4 0.0 0.0 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OR2AG1 OR2AG3 ENSG00000279486 "Olfactory receptor family 2 subfamily AG member 1" Q9H205 11 6783020-6791558 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Fibroblasts - ECM organization" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OTOF "DFNB6, DFNB9, FER1L2" ENSG00000115155 Otoferlin Q9HC10 2 26457203-26558756 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Hearing "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "bone marrow: 6.4;brain: 23.1" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 4.0;Skeletal myocytes: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HDLM-2: 32.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012410 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA012410: AB_1854836" "unprognostic (4.01e-3)" "unprognostic (7.85e-2)" "unprognostic (8.95e-2)" "unprognostic (7.20e-5)" "unprognostic (1.82e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (6.61e-2)" "unprognostic (1.78e-2)" "unprognostic (1.26e-1)" "unprognostic (2.97e-3)" "unprognostic (4.85e-14)" "unprognostic (1.33e-2)" "unprognostic (5.19e-1)" "unprognostic (9.65e-2)" "unprognostic (8.96e-5)" 0.2 0.5 23.1 0.3 16.3 6.4 0.2 0.2 13.1 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.3 0.1 4.1 3.3 0.0 0.0 0.2 0.1 5.2 2.8 0.0 0.1 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.7 0.3 0.3 0.1 4.2 0.5 0.2 1.1 3.0 0.9 0.1 0.3 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.3 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 23.1 16.3 0.2 13.1 4.1 3.3 5.2 2.8 4.0 4.2 3.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.2 0.8 0.3 0.0 0.0 0.1 0.5 0.4 0.0 0.0 P2RX2 "DFNA41, P2X2" ENSG00000187848 "Purinergic receptor P2X 2" Q9UBL9 12 132618776-132622388 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;epididymis: 21.8;prostate: 14.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.6;Endometrial ciliated cells: 2.6;Fibroblasts: 8.3;Gastric mucus-secreting cells: 1.1;Peritubular cells: 3.0" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Group enriched" "Detected in many" 7 "amygdala: 9.2;cerebral cortex: 11.3;hippocampal formation: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "MCF7: 5.1;T-47d: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.12e-1)" "unprognostic (1.49e-2)" "unprognostic (5.92e-2)" "unprognostic (5.94e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (3.12e-1)" "unprognostic (5.79e-3)" "unprognostic (6.75e-2)" "unprognostic (2.92e-1)" "unprognostic (1.11e-2)" "unprognostic (3.66e-2)" "unprognostic (1.88e-2)" "unprognostic (6.21e-2)" "unprognostic (3.05e-1)" "unprognostic (9.12e-2)" 1.1 0.1 9.2 0.6 0.4 0.1 0.2 0.3 11.3 0.7 0.0 2.4 1.1 0.2 21.8 7.2 9.3 0.1 0.0 10.1 1.5 2.5 0.4 4.9 1.9 0.1 0.2 0.3 0.5 0.7 1.3 0.4 0.1 14.1 0.3 0.0 0.1 9.0 0.0 0.2 4.3 0.1 0.0 3.2 1.7 1.5 1.0 0.4 0.2 0.0 0.8 1.0 1.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 5.1 0.1 0.3 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 1.9 0.0 0.6 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 0.4 0.3 11.3 10.1 1.5 0.1 0.2 0.1 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.1 0.1 0.0 0.0 0.1 0.0 0.1 8.3 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028830 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.4;skeletal muscle: 12.4;tongue: 7.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.6;Excitatory neurons: 8.9;Inhibitory neurons: 7.9;Ionocytes: 8.2;Skeletal myocytes: 20.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.7;LHCN-M2: 6.7;RH-30: 4.2;U-87 MG: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA028776: AB_2672771, HPA028777: AB_2672772" "unprognostic (1.81e-2)" "unprognostic (5.15e-3)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-5)" "unprognostic (1.70e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-1)" "unprognostic (2.59e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (2.88e-10)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" 0.3 1.1 0.0 0.3 0.2 0.0 0.1 1.0 2.6 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.3 0.8 1.3 1.0 1.5 0.2 0.1 0.3 0.2 3.4 0.4 0.3 0.1 0.0 1.3 0.8 3.4 0.3 0.0 0.3 0.2 0.7 12.4 0.1 0.1 0.1 0.1 1.6 0.2 1.1 0.6 0.0 0.0 7.7 0.0 0.2 0.1 1.2 0.0 0.4 0.7 0.2 0.1 0.0 0.8 0.1 1.7 0.7 1.2 0.0 0.0 0.0 1.1 0.4 2.9 1.3 0.0 0.1 0.1 0.2 0.0 1.9 0.9 0.0 2.8 0.0 2.4 0.3 0.0 1.2 0.0 9.7 0.0 0.0 2.1 0.6 6.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.2 0.0 0.0 0.2 3.1 1.2 0.1 0.5 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.2 0.0 0.0 11.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 2.6 1.0 1.5 3.4 0.4 3.4 0.1 0.6 1.2 0.2 0.0 0.6 0.3 0.1 0.1 0.8 0.8 0.6 7.6 0.0 0.4 2.4 0.0 0.2 1.8 0.0 0.5 0.0 0.1 0.0 0.0 2.2 1.8 0.5 0.2 3.5 2.7 8.9 0.0 0.4 1.4 0.0 0.7 2.5 0.1 1.8 0.1 0.1 1.7 7.9 0.7 8.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 5.0 3.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 3.2 1.1 0.0 20.8 0.4 1.6 0.4 0.3 0.1 0.4 0.5 0.1 0.1 0.2 PABPC5 PABP5 ENSG00000174740 "Poly(A) binding protein cytoplasmic 5" Q96DU9 X 91434595-91438584 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.4;ovary: 11.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.8;Endometrial stromal cells: 8.3;Horizontal cells: 8.4;Oligodendrocyte precursor cells: 7.5;Peritubular cells: 11.7;Sertoli cells: 13.1;Skeletal myocytes: 11.2;Theca cells: 12.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;HSkMC: 2.8;LHCN-M2: 1.9;RH-30: 8.4;U-2 OS: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000164, HPA000165" Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA000164: AB_1079551, HPA000165: AB_1079552" "unprognostic (1.05e-1)" "unprognostic (2.98e-1)" "unprognostic (3.68e-2)" "unprognostic (2.92e-1)" "unprognostic (1.37e-1)" "unprognostic (1.56e-2)" "unprognostic (1.23e-1)" "unprognostic (3.52e-1)" "unprognostic (2.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.93e-2)" "unprognostic (2.46e-1)" "unprognostic (1.26e-1)" "unprognostic (6.87e-3)" "unprognostic (1.27e-1)" "unprognostic (4.55e-2)" "unprognostic (8.07e-2)" 2.1 7.4 1.1 0.7 1.3 0.0 0.9 1.1 1.5 2.3 0.5 1.5 0.4 3.1 2.5 1.2 1.8 1.3 1.6 1.0 1.4 0.8 0.3 0.9 0.8 1.5 1.3 11.1 0.4 1.2 1.3 0.7 1.4 2.3 0.7 1.2 0.8 2.0 0.5 0.4 0.7 2.9 1.4 1.8 0.7 1.6 1.4 0.2 2.0 0.9 0.5 1.3 1.0 1.7 0.0 0.0 7.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.1 1.5 1.0 1.4 1.5 1.3 1.4 1.4 1.4 1.7 1.3 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.0 12.8 0.1 1.1 0.7 0.0 0.0 1.8 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 8.3 1.3 0.0 0.0 1.7 0.0 0.0 5.0 0.0 0.1 0.0 6.6 1.1 0.0 0.1 8.4 1.8 0.0 0.0 0.0 0.4 0.7 5.9 0.1 3.6 1.0 0.0 4.1 0.0 7.5 3.6 0.0 0.0 11.7 0.0 0.3 0.0 0.1 0.0 3.4 13.1 11.2 4.4 0.2 0.3 0.1 0.3 0.0 0.1 12.0 0.0 0.0 PALM "KIAA0270, PALM1" ENSG00000099864 Paralemmin O75781 19 708935-748329 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 257.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.2;Distal tubular cells: 52.8;Hepatic stellate cells: 63.1;Leydig cells: 48.4;Muller glia cells: 92.8;Proximal tubular cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.9" "Lineage enriched" "Detected in single" 19 "monocytes: 1.9" "Cell line enhanced" "Detected in many" "AN3-CA: 16.6;EFO-21: 20.7;REH: 34.3;SH-SY5Y: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041713, HPA049578" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA041713: AB_10794305, HPA049578: AB_2680822" "unprognostic (9.08e-3)" "unprognostic (2.97e-2)" "unprognostic (2.11e-2)" "unprognostic (3.53e-3)" "unprognostic (1.61e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-1)" "unprognostic (8.39e-2)" "unprognostic (7.62e-2)" "unprognostic (1.36e-2)" "prognostic favorable (9.81e-4)" "unprognostic (2.74e-2)" "prognostic favorable (5.44e-4)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (6.00e-2)" 89.0 23.1 158.4 2.0 140.7 0.7 66.0 86.1 257.8 60.3 54.5 54.4 7.4 43.3 3.3 14.4 47.0 2.8 41.1 165.1 97.0 52.7 7.3 30.0 0.6 106.4 103.6 65.7 5.8 1.2 62.5 6.6 96.9 42.6 0.6 4.6 12.9 8.3 9.6 33.4 20.8 2.4 95.0 23.4 18.0 19.6 112.1 0.6 21.0 1.7 0.2 29.4 41.8 110.5 0.0 7.6 14.6 16.6 0.6 0.2 2.2 0.9 0.0 1.0 0.2 1.9 0.1 0.0 20.7 0.0 0.0 2.7 8.0 0.0 0.4 0.0 14.1 0.0 4.3 9.3 9.4 0.0 0.3 3.0 0.0 0.9 0.0 0.4 0.4 1.6 4.6 0.1 1.1 15.9 1.1 9.4 5.9 1.0 3.2 34.3 0.0 0.2 0.6 0.0 1.7 28.0 7.5 0.1 0.2 4.6 1.8 4.5 0.0 0.0 13.4 16.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 158.4 140.7 86.1 257.8 165.1 97.0 106.4 103.6 96.9 95.0 112.1 110.5 27.2 0.0 1.7 85.2 2.7 7.1 7.2 6.3 1.8 11.4 5.7 5.3 5.8 1.5 4.9 5.5 12.5 0.9 0.2 1.3 52.8 1.4 1.4 3.8 27.0 25.6 0.0 1.3 26.9 0.2 7.2 37.6 1.1 5.9 0.0 1.4 63.1 0.4 1.0 25.2 15.1 0.1 12.2 2.4 5.4 6.6 48.4 1.1 17.8 10.3 0.1 92.8 0.0 16.6 9.8 0.2 1.4 45.1 0.1 10.1 7.2 57.9 0.5 5.7 0.0 2.3 14.1 0.8 7.3 1.1 7.0 1.9 1.1 0.1 0.4 7.2 PALM2AKAP2 PALM2-AKAP2 ENSG00000157654 "PALM2 and AKAP2 fusion" "Q8IXS6, Q9Y2D5" 9 109498325-110172512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.6;naive B-cell: 10.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA058905, HPA074153, HPA076866" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA058905: AB_2683851, HPA074153: AB_2686669, HPA076866: " "unprognostic (7.12e-2)" "unprognostic (1.64e-6)" "unprognostic (7.90e-2)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" "unprognostic (3.19e-1)" "unprognostic (9.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.75e-1)" "unprognostic (8.37e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-1)" "unprognostic (1.19e-1)" "unprognostic (2.05e-3)" "unprognostic (7.77e-2)" "unprognostic (1.98e-4)" "unprognostic (3.36e-5)" 97.0 13.5 21.8 37.3 21.1 9.9 17.5 6.9 22.7 28.5 0.0 17.4 14.8 28.8 8.5 26.5 14.7 37.4 93.8 15.7 18.5 30.8 38.2 69.1 32.2 18.1 26.6 9.3 13.1 14.0 0.1 97.9 20.3 14.9 18.1 3.3 38.0 25.1 17.0 10.1 13.3 48.5 10.5 38.4 18.5 4.6 38.8 45.4 25.6 24.3 31.7 43.0 0.4 26.3 20.6 7.7 112.5 0.1 110.8 93.0 33.4 116.0 141.3 101.6 93.4 134.6 17.9 92.1 30.6 129.6 146.2 28.9 9.5 98.8 185.4 68.9 12.5 9.2 30.4 11.0 75.9 12.4 256.2 109.8 24.7 183.3 280.4 62.5 150.9 14.5 0.3 76.2 204.7 1.2 61.9 31.1 47.2 9.1 62.6 5.5 98.2 25.3 72.4 2.8 25.2 1.5 10.3 9.5 26.4 87.8 4.1 22.2 240.0 94.0 77.9 137.5 108.8 52.5 89.1 52.5 81.4 51.3 73.9 2.9 0.1 1.3 1.0 0.2 0.2 10.6 1.2 1.4 1.2 10.3 0.7 0.8 0.5 2.2 0.0 2.4 3.9 1.4 21.8 21.1 6.9 22.7 15.7 18.5 18.1 26.6 20.3 10.5 38.8 26.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAX1 ENSG00000125813 "Paired box 1" P15863 20 21705659-21718486 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 162.1" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 7.7" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "SCLC-21H: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (9.74e-2)" "unprognostic (3.45e-2)" "unprognostic (3.01e-1)" "unprognostic (2.64e-2)" "unprognostic (1.04e-2)" "unprognostic (2.33e-2)" "unprognostic (4.04e-2)" "unprognostic (2.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (8.08e-2)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 162.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.9 0.0 19.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.5 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 PAX7 Hup1 ENSG00000009709 "Paired box 7" P23759 1 18630846-18748866 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 4.2;skeletal muscle: 5.7;tongue: 4.4" "Cell type enriched" "Detected in some" 284 "Skeletal myocytes: 341.4" "Group enriched" "Detected in some" 6 "breast cancer: 0.5;cervical cancer: 1.5;lung cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 1.4;CAPAN-2: 1.4;U-2 OS: 3.0" "Region enriched" "Detected in single" 17 "midbrain: 4.6" "Region enhanced" "Detected in some" "thalamus: 4.3" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.41e-4)" "unprognostic (2.07e-1)" "unprognostic (5.35e-2)" "unprognostic (3.96e-2)" "unprognostic (4.21e-1)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 3.1 4.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.2 1.3 0.3 0.1 3.1 4.2 2.2 2.4 0.4 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 341.4 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PBOV1 "UC28, UROC28" ENSG00000254440 "Prostate and breast cancer overexpressed 1" Q9GZY1 6 138215986-138218491 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "brain: 3.1" "Cell type enhanced" "Detected in single" "Bipolar cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063021, HPA069649" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA063021: AB_2684923, HPA069649: " "unprognostic (3.32e-3)" "unprognostic (8.23e-2)" "unprognostic (9.35e-2)" "unprognostic (1.22e-1)" "unprognostic (4.77e-2)" "unprognostic (2.51e-1)" "unprognostic (1.35e-4)" 0.0 0.0 0.7 0.0 1.1 0.2 0.0 2.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.1 0.0 0.0 0.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.7 1.1 2.7 0.9 1.2 0.7 0.9 0.6 0.7 0.3 0.8 3.1 0.0 0.0 0.5 0.3 0.0 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 PCDHB1 PCDH-BETA1 ENSG00000171815 "Protocadherin beta 1" Q9Y5F3 5 141051374-141059346 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Cardiomyocytes: 2.7;Respiratory ciliated cells: 2.2;Skeletal myocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA053921 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "HPA053921: AB_2682310" "unprognostic (5.54e-2)" "unprognostic (1.60e-2)" "unprognostic (9.01e-4)" "unprognostic (8.65e-2)" "unprognostic (8.00e-2)" "unprognostic (7.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (8.17e-5)" "unprognostic (3.38e-2)" "unprognostic (9.40e-2)" "unprognostic (1.23e-1)" "unprognostic (5.77e-4)" 0.1 0.2 0.4 0.1 0.4 0.4 0.0 0.9 0.5 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.4 0.1 0.1 0.4 0.2 0.3 0.1 0.1 0.2 0.4 0.3 0.1 0.4 0.3 0.5 0.1 0.4 0.1 0.0 0.5 0.2 0.0 1.4 0.3 0.2 0.0 0.1 0.2 0.3 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.2 0.2 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.5 0.0 0.2 0.1 0.1 0.2 0.2 0.0 0.2 0.2 0.1 0.0 0.2 0.4 0.1 0.0 0.3 0.2 0.2 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.4 0.4 0.9 0.5 0.4 0.2 0.4 0.3 0.4 0.1 0.3 0.4 0.0 0.0 1.1 0.0 0.4 0.0 0.9 0.0 0.0 0.3 0.1 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 2.2 0.4 0.0 1.2 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 PCDHB11 "ME2, PCDH-BETA11" ENSG00000197479 "Protocadherin beta 11" Q9Y5F2 5 141199610-141203779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 4.9;Endometrial stromal cells: 3.5;Fibroblasts: 4.8;Peritubular cells: 3.4;Sertoli cells: 6.6;Skeletal myocytes: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.6;EFO-21: 8.9;U-2 OS: 3.0" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-2)" "unprognostic (1.42e-1)" "unprognostic (6.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.07e-1)" "unprognostic (2.89e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" "unprognostic (1.37e-2)" "unprognostic (9.79e-2)" "unprognostic (6.47e-3)" 1.3 0.6 0.2 0.5 0.5 0.2 0.9 0.9 1.2 1.2 0.0 1.0 0.2 1.5 0.5 0.7 0.9 0.9 0.8 0.5 0.0 0.7 0.2 0.8 0.1 0.3 0.3 1.6 2.6 2.6 0.7 0.6 0.1 0.9 0.3 0.6 0.8 1.0 0.4 0.8 0.4 1.2 0.4 0.6 0.6 0.4 0.0 0.3 0.6 0.6 0.1 0.9 0.6 0.4 0.0 0.1 1.8 5.6 0.1 0.1 1.1 0.1 0.5 0.0 0.0 0.0 0.1 0.0 8.9 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.8 0.0 0.1 0.0 1.4 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.0 2.2 0.0 0.0 0.2 2.2 0.3 1.3 0.1 0.7 0.3 1.3 0.0 0.3 0.1 3.0 2.4 0.0 0.1 0.0 0.0 1.4 0.1 1.5 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.5 0.9 1.2 0.5 0.0 0.3 0.3 0.1 0.4 0.0 0.4 1.9 3.2 0.5 0.0 0.0 0.0 0.7 0.0 0.0 4.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.7 3.5 1.9 2.4 0.0 0.0 1.8 0.0 4.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.1 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 1.0 0.0 3.4 0.1 0.9 0.0 0.9 0.0 0.2 6.6 4.1 1.7 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.7 PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.0;Endometrial stromal cells: 2.8;Fibroblasts: 2.8;Melanocytes: 3.6;Peritubular cells: 2.6;Skeletal myocytes: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;ASC diff: 2.5;EFO-21: 3.0;RH-30: 3.2;U-2 OS: 2.3;U-2197: 2.4" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" 1.3 0.6 0.1 0.4 0.7 0.0 1.2 0.9 1.1 1.9 0.0 1.3 0.2 2.7 0.8 0.4 1.9 1.0 1.4 0.8 0.1 0.6 0.3 1.4 0.1 0.3 0.3 2.2 1.3 1.0 2.0 0.4 0.0 0.9 0.4 0.8 0.6 0.9 0.7 0.5 0.6 1.8 0.1 0.7 0.6 1.1 0.1 0.1 0.6 0.9 0.1 1.2 1.1 0.7 0.0 0.0 0.7 2.7 2.5 1.4 0.4 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.0 0.3 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.5 0.5 3.2 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.6 0.2 2.1 0.4 0.2 0.4 2.3 2.4 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.9 1.1 0.8 0.1 0.3 0.3 0.0 0.1 0.1 0.7 1.9 0.0 1.1 0.0 0.0 0.4 0.0 0.2 0.0 4.0 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.8 0.1 2.8 1.3 1.8 0.0 0.0 0.9 0.0 2.8 0.5 0.1 0.0 0.1 1.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 3.6 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.1 0.0 0.2 0.0 0.3 0.0 2.2 1.6 1.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.1;Early spermatids: 8.1;Horizontal cells: 13.5;Peritubular cells: 8.6;Spermatocytes: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 14.4;SiHa: 12.0;U-2197: 8.5" "Low region specificity" "Detected in all" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 39000 "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007692: AB_2667896, HPA045248: AB_10959599" "unprognostic (2.57e-3)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (8.97e-2)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" "unprognostic (2.11e-2)" "unprognostic (2.38e-2)" "unprognostic (6.60e-2)" "unprognostic (2.57e-2)" "unprognostic (1.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (2.58e-1)" "unprognostic (3.12e-2)" "unprognostic (3.77e-2)" "unprognostic (3.90e-2)" 3.1 2.8 2.3 0.8 3.2 0.1 3.5 2.1 4.0 6.0 0.0 4.6 0.3 7.0 2.4 2.0 4.3 1.9 4.4 2.6 1.3 2.1 1.2 3.0 0.4 1.5 2.3 4.7 4.0 3.6 6.2 1.1 0.7 3.1 0.9 2.3 3.6 1.9 1.6 4.4 1.6 2.6 1.6 2.0 1.9 2.5 3.1 0.4 2.2 1.5 0.3 3.5 3.5 3.3 0.0 0.0 3.3 6.3 5.4 6.4 0.4 0.5 5.5 0.5 1.7 0.1 1.0 0.3 4.5 1.5 2.9 0.3 0.7 1.0 0.5 0.0 0.1 0.0 1.3 0.1 0.2 0.3 0.2 1.2 4.7 0.1 0.2 4.8 0.6 0.2 0.0 5.8 2.3 0.5 0.4 0.0 0.4 0.0 1.1 3.8 4.1 0.0 0.1 0.2 7.6 14.4 12.0 0.3 1.3 0.5 6.1 0.5 1.7 2.2 1.9 8.5 2.2 0.0 0.1 0.1 4.5 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.1 4.0 2.6 1.3 1.5 2.3 0.7 1.6 3.1 3.3 4.1 0.0 4.8 0.0 0.0 0.4 1.1 3.1 0.0 15.1 1.6 2.4 3.3 0.0 3.1 1.8 0.0 0.0 0.2 0.3 0.0 0.9 8.1 0.8 6.3 3.9 3.5 0.0 0.0 2.4 0.0 5.0 0.0 0.9 0.0 1.3 3.3 1.3 0.1 13.5 0.0 0.6 4.1 0.0 0.7 2.1 3.4 0.3 0.0 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.5 8.6 0.0 0.5 0.0 0.8 0.6 1.3 0.0 6.3 3.9 8.0 0.1 0.7 2.8 0.0 0.2 2.5 0.3 0.7 PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.9;Endometrial stromal cells: 10.0;Fibroblasts: 7.3;Horizontal cells: 8.4;Skeletal myocytes: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 19.4;LHCN-M2: 10.5;U-138 MG: 39.3;U-2197: 11.1;U-87 MG: 9.9" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" 3.1 1.9 1.2 1.2 0.9 0.2 2.4 2.1 1.8 2.6 0.0 1.6 0.5 4.5 4.8 0.7 2.2 2.0 2.5 1.6 0.8 2.0 1.0 2.4 0.6 2.0 1.0 6.7 1.9 4.3 2.3 1.2 1.2 1.7 0.9 2.2 1.8 0.9 1.0 1.3 0.9 2.7 1.5 1.1 0.9 1.4 1.3 0.4 1.7 3.3 0.2 1.6 1.5 2.2 0.1 0.3 1.0 19.4 7.8 5.2 0.6 0.8 3.8 0.0 0.3 0.1 0.3 0.0 5.0 0.9 2.1 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 3.3 0.1 0.2 0.1 2.0 10.5 0.4 0.0 0.1 1.5 0.0 0.2 0.1 2.8 0.0 0.6 0.2 0.7 2.6 0.3 0.6 3.9 0.5 7.9 0.0 0.6 39.3 1.7 11.1 2.7 0.1 0.1 0.0 9.9 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.2 0.9 2.1 1.8 1.6 0.8 2.0 1.0 1.2 1.5 1.3 2.2 6.4 3.2 1.5 0.0 0.0 0.8 0.1 1.0 0.0 14.9 1.2 2.4 1.9 5.7 0.6 1.8 0.0 0.0 0.0 0.0 1.9 0.8 1.2 0.6 10.0 4.8 1.8 0.0 0.0 4.7 0.0 7.3 0.5 0.4 0.0 0.2 2.2 0.1 0.1 8.4 0.0 0.0 4.1 0.3 0.9 1.5 4.7 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.7 0.0 5.7 0.1 0.1 0.0 0.7 0.2 1.6 0.0 7.6 5.9 2.9 0.3 0.5 1.4 0.0 0.2 0.4 0.0 0.0 PCDHB3 PCDH-BETA3 ENSG00000113205 "Protocadherin beta 3" Q9Y5E6 5 141100473-141103827 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.8;Cone photoreceptor cells: 2.1;Endometrial stromal cells: 2.6;Horizontal cells: 8.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.3;HAP1: 3.5;SH-SY5Y: 15.2;U-138 MG: 5.3" "Low region specificity" "Detected in all" HPA050296 Uncertain Supported Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050296: AB_2681078" "unprognostic (2.72e-2)" "unprognostic (7.47e-4)" "unprognostic (1.22e-1)" "unprognostic (1.95e-4)" "unprognostic (9.34e-3)" "unprognostic (3.42e-2)" "unprognostic (2.29e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (8.52e-3)" "unprognostic (3.45e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-3)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (5.18e-4)" 1.8 1.2 0.4 0.7 1.1 0.0 1.7 0.6 1.5 1.2 0.0 0.9 0.3 1.5 0.7 0.3 0.9 0.8 1.1 1.0 0.2 1.1 0.1 1.1 0.1 0.3 0.5 1.6 1.2 1.7 1.8 0.4 0.1 1.4 0.5 1.0 0.7 0.5 0.7 0.7 0.5 1.0 0.2 0.4 0.5 3.6 0.6 0.0 0.7 0.9 0.1 0.8 0.9 0.8 0.0 0.0 1.1 3.1 1.9 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.2 1.7 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.6 15.2 0.0 0.1 0.0 0.5 1.9 0.1 0.0 5.3 0.7 0.5 0.3 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.6 1.5 1.0 0.2 0.3 0.5 0.1 0.2 0.6 0.8 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.9 0.8 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.3 0.8 0.4 2.6 1.1 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.8 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 1.8 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.5 0.0 0.1 0.0 0.3 0.0 1.7 1.1 1.8 0.7 0.1 0.3 0.0 0.0 0.4 0.0 0.3 PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 9.7;Endometrial stromal cells: 8.2;Fibroblasts: 9.5;Horizontal cells: 8.4;Peritubular cells: 6.4;Skeletal myocytes: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 8.7;SH-SY5Y: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Intermediate filaments" "HPA014466: AB_1855058" "unprognostic (2.60e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (8.60e-3)" "unprognostic (4.03e-1)" "unprognostic (6.44e-2)" "unprognostic (2.44e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.82e-3)" "unprognostic (1.11e-3)" "unprognostic (2.17e-1)" "unprognostic (3.32e-4)" "unprognostic (5.18e-3)" 3.2 2.1 2.7 0.7 3.0 0.0 3.4 3.3 3.7 3.6 0.3 2.0 0.6 5.4 3.8 1.5 4.0 2.4 2.3 3.2 4.2 1.5 0.3 2.1 0.4 5.0 3.7 4.2 8.5 1.4 2.7 0.1 5.7 2.4 0.9 1.6 2.1 1.9 1.6 1.3 0.9 3.3 5.0 0.7 1.3 0.5 2.7 0.4 1.5 2.1 0.2 2.1 2.1 6.7 0.0 0.0 0.3 1.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.7 5.8 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 3.0 3.3 3.7 3.2 4.2 5.0 3.7 5.7 5.0 2.7 6.7 9.7 0.0 0.5 0.0 0.0 1.1 0.4 0.2 0.6 4.9 2.6 3.8 1.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.4 8.2 4.3 0.0 0.0 0.0 1.7 0.0 9.5 0.0 0.3 0.0 0.1 3.6 0.0 0.1 8.4 0.0 0.0 2.0 0.0 1.1 0.0 1.5 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 0.6 0.0 6.4 0.0 0.7 0.0 0.0 2.5 0.6 0.0 8.7 4.0 1.4 0.5 0.0 2.0 0.0 0.0 0.5 0.0 0.4 PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.7;Cone photoreceptor cells: 16.7;Horizontal cells: 23.5;Skeletal myocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.6;HSkMC: 16.1;T-47d: 19.7;U-2197: 11.6" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077276" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077276: " "unprognostic (2.92e-1)" "unprognostic (2.17e-4)" "unprognostic (1.63e-1)" "unprognostic (3.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.64e-3)" "unprognostic (2.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.06e-1)" "unprognostic (8.83e-3)" 1.6 1.6 3.5 0.4 3.2 0.1 1.1 4.1 2.4 1.3 0.8 1.0 0.8 1.3 0.7 1.7 1.3 1.4 1.0 2.7 3.8 0.5 1.5 1.3 0.4 3.3 3.1 1.3 0.6 2.1 0.8 3.6 3.4 1.4 0.9 2.5 1.8 1.8 1.1 2.0 1.0 1.1 4.2 0.9 2.0 0.5 3.9 0.4 2.1 0.3 0.5 0.8 1.3 3.8 0.0 0.0 14.6 7.5 6.3 2.7 6.9 2.6 0.1 3.6 5.6 0.3 0.9 0.8 9.6 3.7 0.2 0.4 3.5 2.4 2.8 0.9 0.1 0.0 0.3 0.0 2.5 1.5 0.3 16.1 0.4 2.4 1.0 0.4 1.4 0.3 0.0 0.1 9.0 0.1 0.1 0.4 1.4 0.0 0.1 0.2 1.2 0.0 2.4 0.1 2.0 0.7 0.4 0.1 0.4 3.5 19.7 1.9 3.3 6.7 0.4 11.6 0.1 0.2 1.2 0.1 3.4 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 3.2 4.1 2.4 2.7 3.8 3.3 3.1 3.4 4.2 3.9 3.8 5.8 0.0 2.0 0.0 0.9 0.1 2.3 0.6 1.2 27.7 2.2 2.2 3.4 1.5 1.6 1.8 16.7 2.1 1.3 0.7 0.0 1.0 0.0 1.3 7.7 4.8 1.2 0.4 0.0 1.4 1.3 4.8 1.5 2.0 1.3 1.0 4.6 1.7 1.0 23.5 0.0 1.6 0.0 0.0 0.0 0.2 3.4 0.7 1.8 0.0 0.0 5.7 0.0 0.0 0.0 3.1 0.4 2.2 0.5 2.8 0.4 0.5 0.0 6.7 6.6 14.9 3.7 0.4 0.7 1.2 0.4 0.4 0.5 3.0 1.3 1.5 PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Bipolar cells: 2.5;Hepatic stellate cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;ASC TERT1: 25.9;GAMG: 47.4;hTERT-RPE1: 69.8;WM-115: 43.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" 0.8 0.7 1.4 0.7 1.8 0.0 0.6 5.1 1.3 0.8 0.7 1.0 0.2 0.7 0.3 0.7 0.9 0.5 1.6 2.1 2.3 0.5 0.4 0.6 0.4 1.8 1.2 1.1 0.5 0.3 0.6 2.2 2.1 0.5 0.3 3.1 0.7 0.7 1.1 1.7 0.4 0.8 2.4 0.3 0.4 0.8 1.9 0.3 0.8 0.5 0.3 0.6 0.8 2.9 0.0 0.0 0.7 2.4 24.3 25.9 0.9 5.5 10.6 4.2 6.6 0.1 0.2 0.6 9.1 5.6 47.4 3.7 0.1 0.6 6.6 0.2 2.4 0.1 0.1 0.0 4.0 0.4 0.0 19.0 0.3 7.4 0.1 69.8 6.5 1.2 0.0 0.1 0.1 0.0 0.0 0.3 2.9 0.0 0.1 17.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 21.3 9.9 0.5 3.2 7.9 0.8 0.1 0.6 0.1 0.0 0.4 0.0 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 1.8 5.1 1.3 2.1 2.3 1.8 1.2 2.1 2.4 1.9 2.9 0.5 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.1 0.5 0.8 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.2 1.1 0.0 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.6 0.3 0.1 0.1 0.7 0.0 0.1 0.0 0.2 0.1 0.1 PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Bipolar cells: 3.8;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.3;Endothelial cells: 2.2;Fibroblasts: 3.2;Skeletal myocytes: 2.0" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in some" "BJ: 9.3;BJ hTERT+: 15.4;fHDF/TERT166: 23.3;HHSteC: 7.2;HSkMC: 16.5;TIME: 7.5" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" 3.0 4.3 5.3 0.8 6.8 0.0 1.5 5.5 3.7 2.0 0.8 1.3 0.2 2.6 0.4 1.0 1.9 3.9 4.2 5.1 8.4 1.0 0.7 3.1 0.4 10.0 4.2 1.9 1.1 0.3 1.4 2.2 4.5 1.0 0.3 1.4 0.9 1.5 1.3 1.7 0.8 1.7 5.5 1.2 1.0 0.3 5.2 0.9 1.6 1.1 0.4 1.2 2.0 4.6 0.0 0.0 0.1 1.9 0.8 1.4 0.1 9.3 15.4 0.0 0.0 0.0 0.0 0.5 0.0 23.3 0.1 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 4.5 0.0 0.0 5.4 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 2.6 7.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 6.8 5.5 3.7 5.1 8.4 10.0 4.2 4.5 5.5 5.2 4.6 2.2 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 3.8 0.2 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.3 2.2 0.0 0.0 0.0 0.2 0.0 3.2 1.1 0.1 0.0 0.1 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.7 0.0 2.0 1.0 0.0 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 3.2;Cardiomyocytes: 1.8;Fibroblasts: 1.5;Leydig cells: 1.2;Peritubular cells: 2.6;Skeletal myocytes: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.4;BJ: 3.9;fHDF/TERT166: 4.4;HSkMC: 3.4;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA038625: AB_2732480" "unprognostic (2.43e-3)" "unprognostic (2.10e-2)" "unprognostic (1.32e-2)" "unprognostic (4.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.45e-3)" "unprognostic (9.68e-3)" "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.23e-4)" 2.2 1.6 1.8 0.7 1.4 0.0 1.9 2.7 2.5 3.0 0.7 1.5 0.1 2.9 1.9 0.8 3.1 1.4 4.9 2.9 1.5 1.1 0.7 2.0 0.2 3.8 3.2 6.3 1.8 3.8 2.6 0.7 2.6 1.9 0.3 2.3 1.2 2.2 1.0 1.0 0.6 2.1 3.5 0.6 0.9 2.3 2.6 0.8 1.6 1.1 0.2 1.4 1.7 2.2 0.0 0.7 0.3 0.2 2.8 6.4 0.0 3.9 1.3 0.3 0.5 0.0 0.0 0.1 0.4 4.4 0.5 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.4 0.1 0.0 0.2 3.9 1.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.5 0.0 0.2 0.5 0.0 2.3 0.1 0.3 0.4 0.0 2.3 0.6 0.3 0.2 0.0 0.0 0.3 0.0 1.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.4 2.7 2.5 2.9 1.5 3.8 3.2 2.6 3.5 2.6 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 3.2 0.3 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 1.1 0.9 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.4 0.0 1.5 0.5 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.4;Cardiomyocytes: 1.6;Endometrial stromal cells: 1.9;Fibroblasts: 1.3;Horizontal cells: 3.3;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 7.1;BJ: 2.3;EFO-21: 5.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.47e-2)" "unprognostic (4.79e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.85e-1)" "unprognostic (7.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.32e-3)" "unprognostic (7.12e-3)" "unprognostic (3.31e-2)" "unprognostic (2.52e-4)" 1.2 1.2 2.6 0.2 1.7 0.0 0.9 2.2 2.6 1.6 0.1 0.7 0.0 1.4 0.9 0.2 1.2 0.9 3.7 2.5 1.8 0.5 0.6 0.9 0.0 3.8 2.9 2.5 0.9 0.6 1.2 1.7 2.2 0.7 0.2 1.8 0.7 0.8 0.8 0.5 0.2 0.9 3.4 0.2 0.4 1.5 2.9 0.2 0.8 0.9 0.1 0.8 0.9 2.5 0.0 0.0 7.1 0.0 0.0 0.9 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 5.7 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 2.2 2.6 2.5 1.8 3.8 2.9 2.2 3.4 2.9 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.1 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.9 0.1 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Skeletal myocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;BJ: 4.3;HSkMC: 4.3;HUVEC TERT2: 4.3;U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.27e-2)" "unprognostic (4.55e-3)" "unprognostic (2.00e-2)" "unprognostic (6.54e-4)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (5.62e-2)" "unprognostic (3.76e-1)" "unprognostic (6.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.31e-4)" 1.7 1.3 1.6 0.4 1.8 0.0 0.9 3.7 1.7 1.3 0.0 0.9 0.2 1.6 0.8 0.4 0.9 0.8 1.5 2.9 1.5 0.4 0.3 1.0 0.1 2.1 2.4 1.6 2.1 2.3 1.0 0.8 1.7 1.1 0.3 1.5 0.8 1.1 0.7 0.5 0.3 1.5 2.0 0.3 0.4 0.7 2.1 0.2 0.7 1.0 0.1 0.7 0.8 2.5 0.0 0.1 0.8 0.4 3.3 7.4 0.0 4.3 3.4 0.2 0.8 0.0 0.1 0.7 1.4 3.7 1.3 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.3 4.3 0.1 0.0 0.0 2.6 4.3 0.0 0.1 0.2 1.8 0.6 0.2 0.2 0.1 0.0 0.2 0.3 1.2 0.1 0.2 0.0 0.6 1.3 0.2 0.2 0.9 0.3 1.6 0.0 2.8 1.8 0.5 2.4 0.3 0.1 0.2 0.1 6.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 3.7 1.7 2.9 1.5 2.1 2.4 1.7 2.0 2.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364232-141512979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Endometrial stromal cells: 9.2;Horizontal cells: 10.1;Sertoli cells: 6.6;Skeletal myocytes: 5.7" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 15.8;ASC TERT1: 6.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" 1.0 0.6 1.0 0.3 1.6 0.1 1.2 4.9 1.1 2.5 0.0 1.1 0.1 2.0 0.6 0.8 1.4 1.1 1.9 1.2 1.2 0.3 0.2 1.1 0.2 2.2 2.1 2.0 0.6 0.6 0.9 0.6 1.0 1.4 0.3 1.2 0.8 0.9 0.6 0.7 0.4 1.0 1.2 0.2 0.5 0.3 1.2 0.3 0.5 0.7 0.1 1.0 1.3 2.0 0.0 0.4 0.2 0.1 15.8 6.2 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.5 0.6 0.3 0.5 0.6 0.1 0.0 0.3 0.8 0.6 0.1 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.2 1.4 0.0 0.9 0.5 0.1 0.9 0.6 0.1 0.9 0.1 0.3 0.1 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.0 1.6 4.9 1.1 1.2 1.2 2.2 2.1 1.0 1.2 1.2 2.0 1.8 0.0 1.1 0.0 0.2 0.1 0.8 0.1 0.6 11.5 0.3 0.4 2.6 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.4 9.2 1.9 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.2 1.3 0.6 1.4 0.3 0.1 10.1 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.5 0.0 0.1 0.1 1.3 6.6 5.7 1.7 0.0 0.3 0.3 0.0 0.0 0.6 0.9 0.0 0.4 PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.6;Cardiomyocytes: 5.0;Endometrial stromal cells: 4.6;Hepatic stellate cells: 3.6;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.6;T-47d: 5.6;WM-115: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (4.49e-2)" "unprognostic (8.91e-3)" "unprognostic (5.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (3.86e-3)" "unprognostic (2.02e-2)" "unprognostic (5.26e-2)" "unprognostic (7.44e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (4.19e-3)" 1.4 1.1 1.6 0.7 1.8 0.1 1.3 7.2 1.6 2.7 0.0 2.0 0.2 3.2 1.4 0.8 2.0 1.1 2.7 1.7 1.8 0.8 0.5 1.5 0.4 1.8 1.7 3.5 1.2 1.1 1.8 2.3 0.9 1.2 0.4 2.0 1.5 1.6 0.9 1.5 0.8 2.0 0.8 0.9 0.7 0.8 2.0 0.5 1.2 1.0 0.4 1.6 1.5 1.9 0.0 0.3 2.7 0.4 1.3 4.7 0.1 2.1 0.7 1.1 1.1 0.0 0.1 2.0 2.6 3.3 1.0 0.4 0.1 0.4 0.7 0.0 0.2 0.0 0.3 0.2 0.7 0.1 0.1 4.9 0.3 0.2 0.1 1.0 1.6 0.1 0.2 1.1 0.3 0.4 0.7 1.7 0.3 0.0 0.1 1.4 0.4 0.0 0.3 0.1 9.6 0.7 0.1 0.3 0.6 0.6 5.6 0.1 4.8 0.7 0.3 0.7 0.7 0.4 1.7 0.4 0.8 0.7 12.2 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 1.6 1.8 7.2 1.6 1.7 1.8 1.8 1.7 0.9 0.8 2.0 1.9 2.8 0.0 2.2 0.0 0.4 0.0 0.8 0.0 0.0 10.6 0.3 1.0 5.0 1.5 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.5 0.4 4.6 1.8 0.0 0.4 0.0 1.5 0.1 2.2 0.0 0.4 0.0 0.6 3.6 0.7 0.1 1.7 0.0 0.2 0.0 0.3 0.0 0.3 1.2 0.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.1 2.2 1.6 0.4 0.0 0.3 0.7 0.9 0.0 5.2 1.9 0.3 0.3 0.5 0.0 0.3 0.2 0.5 0.2 0.2 PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.3;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.2;Skeletal myocytes: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.3;BJ hTERT+: 20.8;hTERT-RPE1: 10.9;SH-SY5Y: 18.6;T-47d: 8.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.00e-2)" "unprognostic (4.73e-3)" "unprognostic (1.42e-1)" "unprognostic (7.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (4.21e-3)" "unprognostic (6.30e-2)" "unprognostic (4.99e-2)" "unprognostic (1.42e-3)" 0.5 0.4 1.0 0.2 0.9 0.0 0.6 5.9 1.0 1.2 0.0 1.1 0.1 1.3 1.1 0.5 1.0 0.4 1.5 1.1 0.6 0.6 0.4 0.7 0.1 1.5 1.2 1.5 0.7 2.2 0.8 1.3 0.9 0.9 0.3 1.6 0.8 0.8 0.7 1.0 0.4 0.8 1.0 0.4 0.3 0.5 1.3 0.2 1.9 0.5 0.1 0.9 0.7 1.5 0.0 1.6 2.3 0.0 6.6 11.3 0.0 3.3 20.8 4.2 6.1 0.0 0.0 0.5 5.2 0.7 0.2 0.2 0.0 0.1 3.4 0.0 0.3 0.0 0.4 0.2 1.1 0.0 0.0 5.0 0.1 0.0 0.7 10.9 1.7 0.0 0.0 0.1 0.1 0.1 0.6 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.4 18.6 0.0 0.1 0.1 3.7 8.1 0.0 6.7 0.1 0.1 3.1 0.1 0.1 1.9 0.0 0.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 5.9 1.0 1.1 0.6 1.5 1.2 0.9 1.0 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.3 0.3 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.6 0.0 2.8 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.3 PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.4;Cardiomyocytes: 3.5;Horizontal cells: 3.3;Skeletal myocytes: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.28e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (4.10e-2)" "unprognostic (7.68e-2)" "unprognostic (2.30e-2)" "unprognostic (1.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-3)" "unprognostic (7.59e-2)" "unprognostic (3.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.99e-3)" 0.1 0.1 0.6 0.1 0.6 0.4 0.1 3.9 0.8 0.2 0.2 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.8 0.5 0.0 0.1 0.1 0.1 1.1 0.7 0.3 0.1 0.0 0.2 0.2 0.7 0.1 0.1 0.5 0.1 0.0 0.3 0.3 0.1 0.1 0.3 0.1 0.1 0.1 0.9 0.1 0.4 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.2 0.6 0.1 0.6 0.4 0.4 0.1 0.0 0.1 0.3 0.2 0.4 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.6 0.2 0.4 0.6 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.6 0.6 3.9 0.8 0.8 0.5 1.1 0.7 0.7 0.3 0.9 1.2 1.2 0.0 0.6 0.0 0.1 0.0 0.9 0.0 0.0 11.4 0.3 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.1 2.1 1.2 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.2 0.0 0.3 0.4 0.7 0.1 3.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.2 0.0 0.0 0.0 1.3 1.0 0.0 0.0 0.1 0.1 1.5 0.0 0.7 0.0 0.2 0.0 1.7 0.0 5.2 0.9 0.7 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.5 PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402932-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Cardiomyocytes: 1.3;Endometrial stromal cells: 1.5;Horizontal cells: 3.3;Skeletal myocytes: 2.3" "Cancer enhanced" "Detected in some" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.6;HSkMC: 4.0;hTERT-RPE1: 16.9;TIME: 4.6;U-87 MG: 5.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.98e-2)" "unprognostic (7.47e-3)" "unprognostic (9.86e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-2)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-3)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (4.48e-3)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" 1.8 1.6 3.3 0.7 3.5 0.1 1.3 6.6 3.2 2.0 0.4 1.2 0.5 2.5 1.1 1.4 1.9 2.0 1.1 3.7 2.6 0.8 0.4 1.5 0.5 3.6 3.4 2.8 0.8 1.1 0.9 1.0 3.8 1.5 0.7 4.4 1.1 2.2 0.8 1.7 0.6 1.8 3.7 1.1 0.8 0.4 3.6 0.5 1.4 1.2 0.7 1.2 1.4 5.7 0.0 0.1 0.6 1.6 0.1 0.2 0.2 0.7 0.0 0.6 0.6 0.2 0.4 1.3 3.6 2.0 0.3 0.1 0.1 0.2 0.7 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.2 4.0 0.1 0.4 0.3 16.9 1.0 0.0 0.1 0.2 0.3 0.3 0.1 0.5 0.2 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.4 1.1 0.4 0.1 0.5 0.4 0.9 0.4 4.6 0.3 0.3 0.1 2.5 0.2 0.0 0.0 5.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.5 6.6 3.2 3.7 2.6 3.6 3.4 3.8 3.7 3.6 5.7 0.6 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.6 4.5 0.2 0.3 1.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.4 0.2 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.3 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.1 PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141360042-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.2;Cardiomyocytes: 1.4;Endometrial stromal cells: 1.0;Fibroblasts: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.5;ASC TERT1: 9.8;LHCN-M2: 8.2;REH: 7.8" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" 1.5 1.0 2.6 0.6 3.6 0.1 1.1 6.3 2.8 2.1 0.0 1.1 0.2 3.0 0.9 0.9 1.6 1.9 1.8 3.1 3.2 0.7 0.7 1.7 0.3 3.7 3.3 2.8 0.8 1.2 0.9 1.1 3.6 1.3 0.8 1.6 0.8 1.2 0.8 0.8 0.5 1.5 3.0 0.6 0.6 0.5 2.2 0.4 0.7 0.9 0.3 0.9 1.1 5.5 0.1 0.3 2.0 0.2 13.5 9.8 0.1 2.1 2.9 0.6 3.2 0.0 0.3 3.7 1.0 1.7 7.1 0.5 0.4 0.3 1.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.2 2.5 0.5 0.2 0.1 4.7 1.7 0.1 0.2 1.2 8.2 0.5 2.9 0.7 0.1 0.9 0.9 7.8 2.6 0.2 0.2 0.3 1.5 1.6 0.2 0.4 0.4 1.5 3.0 0.2 5.9 2.9 0.6 4.4 3.9 0.2 2.2 0.6 3.1 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.6 6.3 2.8 3.1 3.2 3.7 3.3 3.6 3.0 2.2 5.5 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 2.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.3;ASC TERT1: 49.6;BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (2.71e-3)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-4)" "unprognostic (9.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.25e-4)" 2.8 2.7 3.6 1.1 3.6 0.0 1.8 5.8 3.1 2.0 3.3 1.7 0.7 3.1 2.0 1.9 2.8 1.6 2.9 3.9 6.4 2.2 2.1 2.7 0.4 5.1 4.7 5.7 3.8 20.3 1.7 4.8 5.4 3.0 0.9 3.1 4.7 3.9 2.1 3.8 0.8 2.8 5.3 1.3 1.5 1.9 4.9 1.3 4.5 1.9 0.8 1.9 2.1 6.1 0.0 2.4 0.3 0.0 66.3 49.6 1.3 18.3 0.0 29.2 32.5 2.9 10.0 10.6 23.4 20.5 0.0 13.9 0.0 7.6 16.4 0.0 3.1 0.0 0.0 0.1 6.9 0.0 6.5 17.6 1.5 1.7 9.4 12.6 9.0 0.0 0.2 0.0 1.0 8.1 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.0 0.1 0.0 0.1 0.0 2.0 19.1 0.1 9.2 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.6 5.8 3.1 3.9 6.4 5.1 4.7 5.4 5.3 4.9 6.1 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.2 1.5 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.8 0.5 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.9;Cone photoreceptor cells: 6.2;Horizontal cells: 10.1;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 16.0;EFO-21: 5.4;HSkMC: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (4.77e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.27e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-4)" 3.1 3.1 3.0 0.9 3.6 0.4 2.2 5.0 2.4 2.9 2.9 2.4 0.5 3.2 2.0 1.2 2.9 1.7 2.4 2.5 3.5 1.1 1.3 2.0 0.7 3.6 3.5 6.0 1.2 2.8 1.8 3.1 3.2 1.4 0.7 2.8 2.2 2.4 2.9 2.1 1.0 1.9 3.3 1.5 1.1 0.6 3.7 0.6 2.6 1.5 0.6 1.8 2.3 3.9 0.0 0.1 16.0 0.1 0.5 0.6 0.8 1.4 0.0 0.4 0.9 0.2 0.2 1.4 5.4 0.9 0.2 0.3 0.0 0.3 1.0 0.0 0.3 0.0 0.2 0.1 1.3 0.1 0.1 3.6 1.8 0.8 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.3 0.1 1.1 0.6 0.0 0.0 0.2 0.0 0.1 2.5 0.2 0.2 0.3 0.0 0.1 0.1 0.4 1.2 0.3 2.6 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 3.0 3.6 5.0 2.4 2.5 3.5 3.6 3.5 3.2 3.3 3.7 3.9 3.6 3.2 0.5 0.0 1.0 0.0 1.5 0.0 0.0 6.9 0.6 0.4 3.9 0.0 1.3 0.0 6.2 0.2 0.6 0.4 0.0 0.7 0.0 0.6 3.8 2.6 0.0 0.0 0.0 1.2 0.1 3.3 1.1 0.5 0.0 0.4 1.4 0.7 0.3 10.1 0.0 0.4 0.0 0.0 0.0 0.2 1.8 0.2 0.0 0.0 0.1 2.7 0.0 0.0 0.0 2.0 0.1 1.2 1.5 0.8 0.1 0.3 0.7 2.5 0.0 5.2 3.2 0.2 0.5 0.3 0.1 0.1 0.7 0.8 0.4 0.8 PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 7.9;Fibroblasts: 3.4;Horizontal cells: 3.3;Skeletal myocytes: 5.9" "Cancer enhanced" "Detected in many" "glioma: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 86.7;HSkMC: 26.7;hTERT-RPE1: 72.4" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (8.40e-2)" "unprognostic (4.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-2)" "unprognostic (3.05e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-2)" 5.2 4.6 4.6 1.8 4.7 0.1 4.2 10.8 3.5 4.9 5.0 5.0 0.9 5.7 2.2 3.0 4.4 4.4 4.3 4.5 7.0 2.4 1.5 5.8 1.2 6.0 6.0 8.1 1.7 4.3 2.2 5.5 5.3 3.8 1.7 5.8 3.7 5.5 3.0 3.3 2.1 5.1 7.7 2.7 2.4 1.9 5.0 1.5 4.0 4.1 0.9 3.3 3.8 7.3 0.0 0.0 2.9 86.7 1.9 0.3 0.9 5.7 0.7 2.1 4.3 0.1 5.3 0.7 4.6 11.7 0.8 1.4 0.2 1.0 2.0 0.1 0.6 0.0 0.2 0.0 6.4 0.5 0.1 26.7 0.7 1.7 0.9 72.4 4.6 0.2 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.0 0.6 10.1 1.9 0.0 0.2 0.0 9.3 12.8 0.2 0.0 0.0 1.0 1.0 0.9 11.5 10.3 0.2 0.9 0.1 0.1 0.2 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.6 4.7 10.8 3.5 4.5 7.0 6.0 6.0 5.3 7.7 5.0 7.3 2.2 3.2 1.3 0.0 0.3 0.4 0.8 0.0 0.0 7.9 0.3 0.5 1.4 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 2.1 2.2 0.0 0.0 0.0 0.5 0.1 3.4 0.0 0.3 1.3 0.5 0.4 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 1.9 0.1 0.4 0.0 0.3 0.0 0.7 0.0 5.9 2.2 0.0 0.1 0.5 0.4 0.0 0.0 1.2 0.1 0.2 PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Bipolar cells: 8.4;Endometrial stromal cells: 5.5;Fibroblasts: 10.2;Horizontal cells: 11.8;Skeletal myocytes: 6.6" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Cell line enhanced" "Detected in many" "ASC diff: 200.7;HSkMC: 186.2;U-138 MG: 244.1;WM-115: 382.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" 63.3 64.3 248.0 15.4 241.0 0.2 59.9 221.6 308.1 107.8 165.1 60.4 7.4 81.3 60.8 54.5 62.6 30.2 77.8 232.3 227.5 36.6 29.5 101.9 9.5 236.9 241.0 65.1 34.7 36.8 79.0 37.1 216.6 66.0 20.4 36.3 46.4 40.7 27.6 64.7 32.0 39.5 216.5 22.2 38.7 22.0 263.5 15.7 45.7 26.3 14.8 60.6 80.0 220.8 12.8 7.7 48.1 14.0 200.7 178.3 0.6 58.6 162.6 30.9 32.5 0.0 12.7 43.5 39.7 108.0 111.7 46.2 6.1 20.7 28.2 0.2 20.0 0.1 1.2 1.2 62.6 0.5 1.5 186.2 31.6 46.9 37.2 104.2 19.7 0.0 0.2 1.6 79.2 24.8 1.0 5.4 2.3 0.8 0.1 30.0 97.1 0.4 17.9 13.7 16.6 69.8 17.3 0.6 115.9 16.8 40.0 66.9 22.1 244.1 12.2 46.7 72.2 0.1 0.6 0.7 60.3 0.1 382.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.1 248.0 241.0 221.6 308.1 232.3 227.5 236.9 241.0 216.6 216.5 263.5 220.8 2.5 0.0 0.0 0.0 0.3 0.3 0.5 0.3 8.0 8.4 0.2 1.1 0.8 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.2 1.4 0.3 5.5 1.9 0.0 0.0 0.0 0.2 0.2 10.2 0.0 0.5 0.0 0.2 1.1 0.0 0.3 11.8 0.0 0.2 0.0 0.3 0.3 0.7 1.2 0.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.6 0.0 0.1 0.0 1.0 0.0 6.6 1.7 1.6 0.0 3.9 0.1 0.7 0.1 3.5 0.0 0.5 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596516 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2300.1;tongue: 1216.5" "Cell type enhanced" "Detected in many" "Adipocytes: 681.3;Cardiomyocytes: 764.5;Kupffer cells: 464.0;Proximal enterocytes: 654.2;Smooth muscle cells: 489.7" "Cancer enhanced" "Detected in all" "renal cancer: 107.8;thyroid cancer: 89.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 32.5;eosinophil: 38.1;intermediate monocyte: 63.5;myeloid DC: 16.8;non-classical monocyte: 39.8" "Group enriched" "Detected in many" 12 "dendritic cells: 16.8;granulocytes: 38.1;monocytes: 63.5" "Cell line enriched" "Detected in many" 7 "ASC diff: 482.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056731 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA056731: AB_2683218" "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 451.2 216.3 32.4 33.4 48.0 2.5 388.7 32.9 43.0 76.3 222.0 278.9 72.3 89.0 10.4 151.5 153.5 80.6 480.4 40.0 35.3 127.8 223.4 120.4 24.0 44.5 41.8 240.8 549.3 18.2 39.9 104.8 45.3 91.2 42.6 2.0 60.2 529.5 2300.1 91.9 163.3 62.2 34.8 99.0 173.1 13.3 39.8 13.8 72.1 1216.5 13.5 187.5 95.2 59.4 0.0 37.7 1.5 9.5 482.2 0.8 0.4 0.0 0.0 0.0 0.0 0.0 12.8 0.0 5.3 1.7 1.6 0.0 0.1 0.0 0.0 0.0 1.3 0.2 66.8 0.0 4.5 0.0 0.0 5.3 0.0 0.0 0.0 0.2 2.4 0.0 1.7 0.0 0.2 0.9 0.0 0.4 0.1 0.0 2.1 0.0 0.0 0.3 23.5 2.6 0.5 2.7 0.0 3.0 8.6 2.4 1.3 1.1 0.0 0.0 0.8 2.1 0.1 0.0 0.0 0.1 1.5 0.0 0.0 0.3 32.5 38.1 0.0 63.5 0.1 0.4 0.0 0.0 16.8 1.5 0.0 0.0 2.5 3.3 39.8 0.5 0.0 14.2 32.4 48.0 32.9 43.0 40.0 35.3 44.5 41.8 45.3 34.8 39.8 59.4 681.3 32.1 16.0 154.4 6.0 10.5 279.2 9.2 19.9 0.1 95.9 40.6 764.5 30.0 36.1 378.9 0.0 5.9 3.9 67.7 13.7 7.2 14.9 151.0 52.1 108.0 55.4 9.3 0.4 5.5 0.7 326.9 158.5 347.5 5.1 19.9 199.2 130.5 49.8 0.0 1.2 96.0 6.1 464.0 21.5 6.7 134.2 204.8 90.7 19.7 19.8 8.4 1.0 7.1 26.2 6.2 46.3 44.8 6.4 110.0 654.2 74.2 66.3 0.4 164.3 293.2 489.7 1.8 1.0 12.3 9.2 10.9 5.3 18.7 60.5 157.4 PER2 KIAA0347 ENSG00000132326 "Period circadian regulator 2" O15055 2 238244044-238290102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053136, HPA060510" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA053136: , HPA060510: AB_2684298" "unprognostic (1.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.88e-2)" "unprognostic (9.28e-2)" "unprognostic (2.52e-1)" "prognostic favorable (2.29e-4)" "unprognostic (2.47e-2)" "unprognostic (2.17e-2)" "unprognostic (3.59e-3)" "unprognostic (3.59e-2)" "unprognostic (1.76e-2)" "unprognostic (2.13e-1)" "unprognostic (6.81e-2)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (2.58e-1)" "unprognostic (5.22e-2)" 12.2 3.3 4.7 5.0 5.2 8.4 14.2 7.2 5.8 11.9 2.4 7.6 5.1 10.2 5.7 13.6 7.9 12.3 5.7 5.7 5.1 3.9 12.4 7.1 4.7 5.2 5.7 7.8 14.4 4.2 9.0 2.9 4.4 9.3 6.2 5.1 14.1 8.9 11.4 17.0 8.0 4.9 5.4 4.8 13.4 11.8 4.7 4.1 8.8 7.6 6.2 8.7 8.2 4.7 1.6 11.7 2.4 4.2 0.1 1.2 8.2 1.1 4.1 1.5 1.4 1.8 5.8 10.3 1.2 2.7 1.5 8.6 2.4 3.5 2.2 2.9 1.7 9.1 6.2 8.2 2.0 13.8 9.2 1.6 8.3 1.8 6.1 1.5 0.8 4.2 4.5 6.3 1.3 7.7 6.9 15.2 3.5 7.6 2.3 16.5 5.5 3.3 1.5 3.3 9.7 1.2 2.9 6.3 1.8 0.7 5.9 8.5 2.1 3.6 4.2 2.8 4.1 7.1 1.8 12.3 6.7 5.9 4.5 2.1 1.2 0.3 1.0 2.2 1.6 1.5 1.6 1.2 1.4 1.5 1.5 1.6 1.0 1.2 2.1 1.8 1.2 0.3 4.7 5.2 7.2 5.8 5.7 5.1 5.2 5.7 4.4 5.4 4.7 4.7 24.9 16.0 30.1 18.6 9.9 73.9 61.7 21.3 38.1 20.6 67.8 33.8 5.7 31.5 46.9 27.6 2.1 9.2 27.0 22.5 7.9 7.5 9.6 69.7 30.1 15.6 24.6 6.9 20.9 10.4 6.3 39.8 52.5 86.1 9.5 3.3 11.4 35.8 3.9 11.8 13.9 35.1 18.3 10.1 25.3 4.7 11.1 12.4 24.9 5.6 5.3 13.5 2.1 9.0 7.2 7.6 35.3 18.4 10.9 15.0 10.9 5.5 44.2 7.8 6.6 110.1 32.2 31.3 17.0 38.4 85.4 13.0 13.6 3.7 36.9 33.9 PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 204.8;Leydig cells: 205.9;Oligodendrocytes: 67.3;Peritubular cells: 149.7" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cell line enriched" "Detected in some" 6 "JURKAT: 29.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" 57.8 3.5 12.2 3.1 17.7 0.2 66.1 14.3 15.1 140.6 7.9 11.6 1.5 5.7 29.0 10.6 15.0 46.4 127.7 10.1 16.1 1.5 0.7 11.4 2.2 15.3 14.2 3.4 5.6 0.9 8.4 2.4 15.8 31.3 7.9 0.0 14.0 34.2 15.1 51.7 4.5 8.4 13.4 1.3 22.1 14.7 16.4 2.4 23.2 33.6 6.0 116.1 127.6 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.9 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 29.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.8 0.6 19.7 5.7 0.0 1.3 6.4 2.2 0.5 13.5 0.0 0.5 66.1 3.3 12.2 17.7 14.3 15.1 10.1 16.1 15.3 14.2 15.8 13.4 16.4 19.3 10.9 0.0 1.5 3.3 0.7 21.5 0.1 0.0 0.6 0.0 0.4 0.4 4.5 0.0 0.6 1.8 0.0 0.0 0.4 0.0 1.9 0.1 10.8 0.1 0.2 11.0 0.0 0.0 0.1 0.0 0.0 204.8 4.1 0.1 0.0 0.0 10.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 39.6 19.0 205.9 1.9 10.6 3.7 0.0 0.0 0.0 0.0 67.3 0.1 0.0 149.7 0.6 0.1 0.0 0.2 0.0 0.0 0.0 7.7 4.2 2.4 1.3 0.4 18.5 0.1 3.5 0.3 0.0 0.2 PIH1D1 "FLJ20643, MOT48, NOP17, Pih1" ENSG00000104872 "PIH1 domain containing 1" Q9NWS0 19 49446298-49453497 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047258 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA047258: AB_10964561" "unprognostic (2.28e-1)" "unprognostic (1.56e-1)" "unprognostic (2.14e-1)" "unprognostic (8.99e-2)" "unprognostic (7.77e-3)" "unprognostic (9.66e-2)" "unprognostic (1.23e-3)" "unprognostic (1.93e-1)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (5.13e-2)" "unprognostic (1.22e-2)" "unprognostic (1.86e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.48e-1)" "unprognostic (2.86e-2)" 38.0 37.1 31.4 26.8 32.0 34.5 37.1 31.5 39.5 38.0 33.8 40.4 43.5 32.4 13.2 45.0 39.7 27.0 31.5 33.0 31.8 41.4 47.7 30.5 43.6 31.7 30.9 29.9 39.7 50.4 34.5 33.1 32.0 39.6 29.5 11.8 49.5 33.8 67.5 45.3 37.2 26.3 31.9 39.4 41.3 17.8 33.1 46.1 37.1 57.6 36.1 33.0 39.4 31.8 133.6 67.0 84.6 130.3 40.1 37.2 54.0 52.9 68.8 79.8 122.3 72.4 89.6 89.1 48.6 56.7 20.0 79.9 44.8 96.6 46.2 85.5 85.1 79.9 89.6 93.0 63.1 86.7 115.3 43.5 40.4 59.0 55.8 74.8 74.8 79.2 119.5 76.8 50.5 59.9 98.4 173.3 101.1 118.4 63.2 83.1 93.6 90.4 65.1 107.2 109.2 158.0 54.3 91.2 53.2 41.1 44.0 104.3 44.9 66.9 52.0 26.9 84.2 205.5 172.8 49.8 36.6 93.6 47.5 166.8 104.5 121.0 88.3 104.0 75.6 116.1 98.8 94.9 105.1 110.1 79.5 73.4 11.8 103.7 108.7 100.2 158.3 107.0 31.4 32.0 31.5 39.5 33.0 31.8 31.7 30.9 32.0 31.9 33.1 31.8 45.5 38.5 36.6 10.7 54.8 55.8 61.9 80.2 59.7 20.9 46.8 50.0 11.2 41.5 46.4 20.2 18.8 101.7 48.8 48.6 62.6 74.1 18.1 47.4 24.1 39.2 57.5 33.4 10.5 46.3 116.5 59.9 43.8 30.6 52.6 30.8 35.3 44.3 71.2 23.5 8.5 63.9 38.7 40.8 55.7 9.9 62.4 40.7 64.0 11.2 59.0 55.0 40.2 10.1 10.9 47.3 75.4 47.0 60.3 65.6 90.2 115.9 59.4 22.6 26.3 44.5 46.8 40.6 29.9 49.0 67.1 94.0 50.4 48.2 59.4 66.2 PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993802-91040872 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 26.2;Cytotrophoblasts: 32.6;Distal tubular cells: 49.0;Extravillous trophoblasts: 31.1;Hofbauer cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 76.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 76.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.54e-4)" "prognostic unfavorable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" 11.9 13.9 13.2 6.6 15.7 30.0 7.4 16.5 20.1 9.2 20.2 14.6 2.8 10.5 4.2 5.9 7.2 11.0 20.7 13.3 20.4 10.0 3.8 5.5 6.9 16.5 16.4 10.6 3.3 10.9 7.9 8.8 18.2 8.7 4.8 11.0 7.3 12.2 13.5 6.5 5.3 13.5 16.4 8.3 6.5 6.9 17.5 9.5 6.6 14.8 5.4 9.9 6.6 21.0 4.8 2.9 16.8 10.2 27.2 30.6 3.5 19.3 24.2 10.2 15.1 1.9 8.1 9.4 2.6 19.9 10.3 1.1 4.2 7.0 13.6 8.1 7.3 13.9 2.9 1.5 23.6 3.3 12.2 17.2 4.4 12.8 9.6 27.4 9.8 2.7 7.4 31.0 35.6 3.3 10.4 9.5 8.6 0.0 9.8 3.9 6.9 11.2 14.9 3.0 2.0 9.7 1.5 6.6 28.4 11.4 0.2 6.3 15.1 18.5 7.1 11.2 9.0 12.0 7.0 6.0 31.6 6.4 25.2 0.9 11.6 10.8 1.3 5.9 2.3 2.7 3.1 1.7 10.8 1.9 4.8 1.9 76.9 2.4 2.2 6.0 2.8 6.1 13.2 15.7 16.5 20.1 13.3 20.4 16.5 16.4 18.2 16.4 17.5 21.0 26.2 0.0 2.8 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.5 11.2 0.0 0.0 3.1 9.2 0.0 32.6 7.7 0.0 49.0 18.0 0.0 0.8 11.7 5.2 0.0 0.0 0.0 8.9 31.1 18.7 0.0 1.0 8.8 4.1 0.0 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 3.6 0.0 0.0 0.0 0.0 15.8 0.0 0.0 2.1 0.0 0.0 13.1 1.5 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 10.9 3.7 14.3 0.0 0.0 PITX3 ASMD ENSG00000107859 "Paired like homeodomain 3" O75364 10 102230186-102241512 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.5;skeletal muscle: 16.5;tongue: 6.0" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 22.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "midbrain: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "RH-30: 30.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 9.1" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.13e-2)" "unprognostic (4.07e-1)" "unprognostic (5.15e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (6.04e-5)" "unprognostic (6.30e-3)" "unprognostic (2.02e-1)" "unprognostic (6.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.73e-2)" "unprognostic (1.76e-2)" "unprognostic (6.76e-3)" "unprognostic (4.13e-2)" 1.2 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.1 0.2 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 16.5 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.0 5.5 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 22.1 0.3 1.4 1.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 PLA2G2A "PLA2B, PLA2L" ENSG00000188257 "Phospholipase A2 group IIA" P14555 1 19975431-19980416 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" "Antimicrobial, Bacteriolytic enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 1302.4;intestine: 1973.9;placenta: 756.7;urinary bladder: 813.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 536.5;Exocrine glandular cells: 1031.5;Fibroblasts: 656.0;Intestinal goblet cells: 393.6;Paneth cells: 574.1;Prostatic glandular cells: 921.1;Undifferentiated cells: 861.9" "Cancer enhanced" "Detected in all" "prostate cancer: 875.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 645.0;OE19: 2384.4" "Not detected" "Not detected" HPA015236 Enhanced "Secreted to blood" NA NA 1000000 680000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "HPA015236: AB_10601047" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (2.79e-2)" "unprognostic (7.85e-3)" "unprognostic (8.71e-2)" "unprognostic (9.27e-2)" "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.49e-4)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-15)" "unprognostic (2.72e-2)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" 1302.4 7.0 0.1 280.2 0.1 0.0 27.4 0.1 0.7 5.4 2.9 1474.0 786.8 4.3 3.3 29.3 14.8 57.7 137.4 0.0 0.2 6.6 238.6 16.8 5.4 0.6 0.7 44.1 7.8 0.9 2.5 756.7 0.2 203.9 1668.0 0.1 24.6 6.1 6.0 18.1 1973.9 164.4 0.1 0.4 11.6 36.8 1.3 1.7 11.1 114.2 15.0 813.6 12.1 0.1 0.0 0.0 1.6 0.0 248.3 0.0 8.5 0.0 0.1 0.1 0.0 11.2 0.0 0.0 1.1 0.0 0.8 18.7 0.0 0.0 0.0 0.1 0.3 0.0 0.3 645.0 0.0 0.1 1.1 2.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.2 0.4 2384.4 0.0 0.0 0.0 7.6 0.0 198.2 1.0 4.7 0.0 20.1 0.0 31.1 0.1 0.0 0.0 0.0 0.0 44.7 0.2 0.4 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.7 0.0 0.2 0.6 0.7 0.2 0.1 1.3 0.1 20.6 6.4 6.7 0.0 9.1 13.9 10.8 0.2 0.6 0.9 1.0 0.8 14.9 12.8 9.3 0.0 0.0 3.6 0.4 536.5 1.9 0.7 4.0 0.7 43.1 6.9 62.3 13.5 0.0 1031.5 4.6 656.0 6.1 0.6 4.5 0.0 30.0 310.9 9.5 0.0 0.0 393.6 2.0 18.8 31.1 11.6 171.2 3.5 14.2 0.0 0.0 0.0 0.0 0.0 0.0 4.7 574.1 1.2 2.6 921.1 328.2 0.2 1.9 0.0 0.0 2.4 37.8 0.9 1.5 4.9 16.8 6.8 6.2 0.1 861.9 32.2 PLAAT5 "HRASLS5, HRLP5, iNAT, PLAAT-5" ENSG00000168004 "Phospholipase A and acyltransferase 5" Q96KN8 11 63461404-63491194 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 16.5;pancreas: 13.6;testis: 53.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Syncytiotrophoblasts: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 3.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 64 "basophil: 5.4;eosinophil: 16.4" "Lineage enriched" "Detected in single" 97 "granulocytes: 16.4" "Group enriched" "Detected in some" 5 "HAP1: 11.4;NB-4: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042493 Uncertain "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA042493: AB_10797499" "unprognostic (3.16e-1)" "unprognostic (3.45e-2)" "unprognostic (2.83e-3)" "unprognostic (4.24e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (7.11e-3)" "unprognostic (2.14e-1)" "unprognostic (6.66e-2)" "unprognostic (9.46e-2)" "unprognostic (8.89e-3)" "unprognostic (3.15e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-5)" "unprognostic (1.52e-1)" "unprognostic (1.21e-2)" "unprognostic (2.57e-3)" "unprognostic (4.50e-4)" 16.5 0.2 1.2 0.3 0.9 0.1 3.3 0.7 0.8 0.1 0.0 0.7 0.2 0.5 0.2 0.8 0.9 0.6 0.6 1.0 1.3 0.1 0.0 0.6 0.1 1.5 0.5 0.6 13.6 0.0 0.0 0.0 1.0 0.4 0.2 0.5 0.8 1.3 0.1 0.2 0.3 1.4 1.1 0.1 0.5 53.4 0.8 0.0 0.1 0.1 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.7 0.8 1.0 1.3 1.5 0.5 1.0 1.1 0.8 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLEKHG2 "ARHGEF42, CLG, FLJ00018" ENSG00000090924 "Pleckstrin homology and RhoGEF domain containing G2" Q9H7P9 19 39412669-39428415 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Leukodystrophy, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 86.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017973, HPA048054" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA017973: AB_2669719, HPA048054: AB_2680241" "unprognostic (3.55e-1)" "unprognostic (6.73e-2)" "prognostic unfavorable (3.53e-4)" "unprognostic (3.97e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-3)" "unprognostic (1.24e-2)" "unprognostic (4.48e-2)" "unprognostic (1.39e-1)" "unprognostic (8.09e-2)" "unprognostic (2.10e-1)" "unprognostic (4.99e-1)" "prognostic unfavorable (3.79e-8)" "unprognostic (8.01e-2)" "unprognostic (3.90e-2)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" 32.6 10.7 4.6 22.8 3.8 22.1 20.3 4.6 7.5 28.2 11.3 24.5 8.1 31.2 4.4 10.1 24.9 17.4 25.6 4.3 3.7 27.7 8.0 42.2 20.7 7.1 4.4 20.1 7.1 5.2 12.2 23.0 5.1 21.0 5.2 4.6 8.4 15.1 6.3 9.0 18.9 18.5 4.7 33.4 15.6 15.7 9.3 21.1 19.1 4.9 18.3 20.9 17.4 5.2 8.5 40.8 73.0 39.9 6.9 9.0 10.6 21.9 17.3 14.9 12.8 26.5 14.9 14.7 15.8 28.8 12.4 2.8 11.1 19.4 7.9 49.3 10.2 19.3 23.5 12.4 11.9 2.2 23.1 20.7 3.3 17.9 8.7 25.8 19.3 41.7 13.2 16.9 24.1 17.0 24.2 7.5 17.3 7.8 3.9 86.1 8.9 4.6 12.7 15.4 2.0 23.6 4.9 1.8 7.0 25.2 21.9 21.8 24.8 38.8 30.0 14.5 14.4 12.6 4.1 21.4 21.6 8.7 22.0 1.3 0.5 0.1 1.4 0.2 0.9 1.2 0.7 0.8 0.3 1.1 1.0 1.2 0.8 0.4 0.7 1.4 1.3 1.1 4.6 3.8 4.6 7.5 4.3 3.7 7.1 4.4 5.1 4.7 9.3 5.2 30.4 6.4 27.4 1.6 9.7 4.0 5.5 2.9 6.8 0.6 4.6 11.7 6.4 2.8 6.4 0.0 0.0 0.8 8.7 5.0 0.0 5.6 14.2 11.9 20.1 17.7 1.2 1.7 0.5 4.9 2.9 16.9 13.3 30.4 2.5 6.9 8.2 0.8 9.9 0.0 0.8 3.7 0.0 12.8 21.1 19.8 7.2 25.6 5.4 2.8 5.4 1.1 4.1 2.5 0.3 4.2 2.1 8.2 9.1 3.0 2.6 0.2 2.2 2.4 6.6 64.5 26.8 2.5 4.1 6.5 2.8 1.1 12.2 2.4 3.1 1.9 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 392.7;Hepatic stellate cells: 779.6;Leydig cells: 1092.6;Peritubular cells: 398.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 710.0;ASC TERT1: 351.8;HSkMC: 438.1;U-2197: 660.4" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 168.4 53.0 93.9 33.6 94.2 13.1 139.8 87.3 105.9 294.6 50.7 56.7 24.0 107.2 56.2 51.3 122.5 66.3 84.6 88.3 90.6 91.4 182.0 87.0 22.4 107.5 108.1 81.9 36.8 130.2 23.1 225.5 87.7 102.8 41.8 19.0 76.2 169.7 50.9 82.1 45.8 65.6 86.8 23.3 66.0 37.3 113.2 29.8 327.6 63.0 19.9 139.2 142.8 88.6 3.3 10.8 14.1 1.5 710.0 351.8 34.5 39.3 39.7 35.5 17.4 31.8 6.2 5.2 4.6 59.3 39.4 5.9 2.1 0.8 7.4 0.0 9.4 1.3 4.4 44.5 17.3 0.1 0.0 438.1 3.0 34.2 28.6 25.1 34.1 0.4 2.9 0.1 39.0 3.2 0.1 0.5 43.3 9.2 42.6 0.1 0.1 1.7 6.1 32.6 0.4 28.1 12.4 16.1 4.2 42.6 5.2 0.0 21.6 176.2 14.4 660.4 1.8 0.0 0.0 0.0 31.0 1.7 12.7 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 93.9 94.2 87.3 105.9 88.3 90.6 107.5 108.1 87.7 86.8 113.2 88.6 148.5 25.6 18.9 0.0 7.2 0.0 19.8 0.0 35.3 3.9 12.2 31.2 0.0 44.3 13.0 22.0 0.0 127.0 1.1 8.1 21.5 21.5 7.9 13.9 139.4 148.3 2.4 8.0 0.0 9.2 9.8 392.7 5.6 16.3 3.8 8.1 779.6 132.6 38.8 0.0 0.0 8.5 0.0 35.2 0.0 28.3 1092.6 14.9 0.0 0.0 0.9 136.0 0.0 0.0 0.0 7.9 5.9 398.7 7.1 20.8 15.5 21.3 4.4 4.1 138.1 179.7 107.2 4.5 3.4 16.4 0.0 214.9 5.0 22.4 7.2 20.1 PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1508.4;Oligodendrocytes: 470.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Cell line enhanced" "Detected in some" "HHSteC: 19.4;U-2197: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" 12.4 9.4 13.3 7.3 14.1 5.2 11.5 9.6 13.3 12.7 16.8 5.3 4.2 10.7 3.5 7.5 10.1 17.4 10.2 11.3 25.6 10.7 3.1 17.1 2.4 18.0 17.3 9.4 3.6 16.2 3.3 4.7 19.2 7.6 4.6 18.2 6.2 7.7 5.0 15.5 7.1 16.2 16.2 9.4 3.8 5.9 22.3 2.5 6.8 10.0 2.8 8.5 8.9 29.1 0.0 0.0 5.8 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 7.7 2.2 1.8 0.0 0.0 0.7 2.8 8.6 0.4 19.4 0.0 0.0 7.7 0.6 0.0 2.3 8.9 0.0 0.0 0.1 1.7 0.9 1.1 0.6 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 0.2 2.4 0.4 0.0 1.8 0.8 0.9 0.0 7.6 3.9 45.9 0.0 0.1 0.0 0.0 3.5 0.1 0.0 10.7 57.5 11.8 1.3 33.4 2.7 0.0 0.0 0.3 36.0 0.0 0.0 0.0 81.6 4.4 37.3 1.6 0.0 17.7 13.3 14.1 9.6 13.3 11.3 25.6 18.0 17.3 19.2 16.2 22.3 29.1 101.4 16.0 8.9 131.9 2.6 36.8 23.8 12.3 41.5 44.2 14.4 45.3 10.9 15.7 10.9 5.5 8.4 0.9 2.9 7.1 0.0 6.9 2.9 16.5 7.6 45.3 3.0 10.5 190.9 0.0 8.1 97.2 1.1 19.4 31.6 80.9 82.1 4.2 94.3 1.7 59.9 27.3 8.2 91.3 46.3 2.1 19.3 147.7 7.2 1508.4 94.5 25.5 5.2 158.3 470.2 1.0 16.6 57.2 3.8 5.5 16.0 22.2 3.0 73.6 19.7 110.1 12.7 1.6 1.2 35.5 38.1 1.2 4.2 71.4 8.8 11.7 PLXNA1 "NOV, PLXN1" ENSG00000114554 "Plexin A1" Q9UIW2 3 126988594-127037392 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007499, CAB012483" Uncertain Supported Nucleoplasm,Cytosol NA NA 10000000 "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012483: , HPA007499: AB_1079637" "unprognostic (1.87e-1)" "unprognostic (1.11e-1)" "unprognostic (4.38e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (1.79e-2)" "unprognostic (9.06e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (3.77e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (5.64e-5)" "unprognostic (4.50e-3)" "unprognostic (7.62e-3)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 11.2 7.6 13.9 7.0 13.0 1.0 9.6 0.6 16.4 11.6 0.5 9.1 3.4 10.9 2.3 11.3 10.2 4.8 15.8 14.0 7.9 8.6 3.2 14.7 6.3 5.5 5.6 13.8 9.3 24.0 5.5 8.2 5.6 9.3 1.9 1.7 12.9 6.3 10.9 15.1 7.9 5.2 1.3 13.2 7.9 9.0 14.8 6.3 9.6 6.1 4.2 9.8 10.0 5.5 45.3 21.1 22.8 18.1 29.3 32.7 36.3 26.3 22.2 14.8 14.7 70.2 20.6 5.0 38.6 28.4 20.0 68.2 11.7 51.6 6.1 7.2 18.6 0.7 13.4 18.3 19.2 5.4 3.6 32.8 35.4 27.4 21.2 14.9 7.5 14.7 26.3 9.1 16.1 26.3 10.6 9.9 22.0 14.2 18.5 14.0 58.0 14.1 12.9 89.4 20.2 22.1 19.1 17.9 24.7 14.7 28.8 33.9 28.0 23.6 30.0 43.4 28.1 5.5 3.9 9.8 33.9 10.2 25.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.9 13.0 0.6 16.4 14.0 7.9 5.5 5.6 5.6 1.3 14.8 5.5 1.9 48.1 4.1 8.8 1.8 15.8 5.6 23.4 6.2 6.7 6.6 7.4 13.0 1.5 18.6 12.9 4.2 21.8 0.8 3.6 0.0 8.9 4.4 5.0 10.0 3.8 9.6 0.4 22.1 6.9 2.5 13.8 7.1 5.6 0.0 20.8 2.2 0.9 13.1 20.2 11.3 4.0 0.0 7.4 12.8 1.0 7.8 7.4 8.8 5.6 1.0 2.5 1.0 13.6 3.6 17.0 2.3 6.4 3.1 21.3 7.4 1.5 11.2 3.3 6.6 6.4 9.9 5.3 9.5 6.7 16.1 7.3 2.2 4.7 5.1 9.5 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Cardiomyocytes: 13.1;Cytotrophoblasts: 27.6;Extravillous trophoblasts: 14.5;Fibroblasts: 14.7;Hofbauer cells: 18.0;Syncytiotrophoblasts: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" 24.6 13.2 5.0 17.3 5.0 7.6 16.2 4.6 5.4 33.6 7.0 16.8 9.4 35.0 27.3 21.0 23.0 21.7 15.2 4.2 5.9 15.6 13.2 16.0 10.4 5.5 6.1 36.5 8.3 25.2 5.4 32.7 5.4 28.4 16.9 5.8 13.9 28.4 5.5 13.7 11.2 37.1 5.3 12.4 11.3 5.8 5.5 16.4 12.1 13.9 9.5 22.5 18.8 6.0 10.9 12.4 46.5 47.8 76.5 88.5 44.8 47.0 43.7 66.0 71.1 58.9 78.1 0.1 28.6 61.6 73.1 7.9 35.6 1.2 69.3 19.4 27.4 18.1 12.1 27.2 30.8 47.7 0.2 51.1 14.6 35.0 1.0 40.1 56.6 0.3 41.5 0.3 101.0 7.9 30.9 27.2 20.3 11.5 34.8 1.5 72.5 0.2 12.3 30.3 9.7 29.5 89.1 6.2 13.3 21.4 42.3 18.0 56.8 127.0 24.9 10.8 49.7 0.4 0.1 0.3 32.6 48.9 103.1 0.1 0.1 0.0 2.0 0.7 1.7 0.2 1.0 1.7 0.5 0.3 1.0 1.5 0.1 1.9 0.4 1.0 0.9 0.5 5.0 5.0 4.6 5.4 4.2 5.9 5.5 6.1 5.4 5.3 5.5 6.0 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 27.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 14.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 21.2 0.5 0.0 0.0 0.0 POU4F1 "BRN3A, RDC-1" ENSG00000152192 "POU class 4 homeobox 1" Q01851 13 78598362-78603552 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 9.3;retina: 2.6" "Cell type enriched" "Detected in some" 10 "Skeletal myocytes: 28.6" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 4 "medulla oblongata: 9.3;midbrain: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 14.1;HEL: 15.5;JURKAT: 12.2;REH: 10.9;RH-30: 17.9;SCLC-21H: 17.1;U-266/70: 16.1" "Group enriched" "Detected in some" 23 "midbrain: 2.5;pons and medulla: 2.1;thalamus: 2.2" "Region enhanced" "Detected in some" "medulla oblongata: 4.1" HPA068024 Enhanced Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA068024: AB_2685943" "unprognostic (6.70e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-4)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (6.30e-2)" "unprognostic (6.00e-2)" "unprognostic (1.70e-2)" "unprognostic (9.17e-2)" "unprognostic (8.98e-2)" "unprognostic (9.95e-2)" "unprognostic (1.53e-1)" "unprognostic (4.75e-3)" 0.0 0.0 0.4 0.1 0.3 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.5 9.3 5.2 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 2.6 0.0 0.0 0.4 0.0 0.0 0.0 1.7 0.0 0.0 0.9 0.8 0.7 0.0 0.1 0.8 0.0 0.0 0.8 0.0 0.7 2.7 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.6 0.0 5.1 0.0 0.0 0.0 14.1 15.5 0.0 2.0 0.0 7.7 4.4 0.0 0.1 0.0 0.0 0.0 0.0 12.2 3.1 0.0 0.7 0.0 1.2 1.4 0.0 2.1 0.0 10.9 17.9 0.0 0.0 0.0 17.1 0.2 0.0 0.0 0.7 0.2 0.0 1.5 0.2 0.0 0.0 0.3 0.0 16.1 5.1 0.0 0.0 8.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.2 0.4 0.6 9.3 5.2 1.6 1.7 0.8 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.1 2.8 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.8 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 2.0 0.0 28.6 0.1 2.5 2.7 0.0 0.4 0.0 0.1 0.0 0.1 0.0 PPDPFL C8orf22 ENSG00000168333 "Pancreatic progenitor cell differentiation and proliferation factor like" Q8WWR9 8 49054311-49076093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 948.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "glioma: 0.7;renal cancer: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "HEL: 1.3" HPA060329 Uncertain NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 50: Fibroblasts - ECM organization" "HPA060329: AB_2684255" "unprognostic (6.33e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.06e-10)" 2.6 0.1 0.2 0.0 0.6 0.0 1.1 0.6 0.5 0.0 0.2 0.2 0.0 0.0 0.0 2.4 0.1 0.0 1.6 0.3 1.4 0.0 0.1 0.1 0.0 1.0 0.2 0.1 0.1 0.0 0.3 0.0 1.1 2.3 0.0 0.3 9.8 0.2 948.1 1.7 0.2 0.0 0.5 0.0 0.1 0.2 0.4 0.0 0.3 112.8 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.6 0.5 0.3 1.4 1.0 0.2 1.1 0.5 0.4 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRDM11 PFM8 ENSG00000019485 "PR/SET domain 11" Q9NQV5 11 45095806-45235110 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 60.0;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057072 Approved NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "HPA057072: AB_2683328" "unprognostic (3.32e-4)" "unprognostic (3.94e-2)" "unprognostic (3.01e-1)" "unprognostic (1.71e-3)" "unprognostic (4.27e-2)" "unprognostic (2.23e-2)" "unprognostic (7.10e-4)" "unprognostic (7.06e-2)" "unprognostic (1.41e-1)" "unprognostic (2.23e-1)" "unprognostic (9.57e-5)" "unprognostic (1.60e-1)" "unprognostic (4.93e-6)" "unprognostic (9.25e-2)" "unprognostic (2.88e-1)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" 5.5 4.3 8.8 2.6 8.2 2.5 4.5 7.1 10.6 11.0 5.1 11.2 2.1 13.0 3.0 6.6 10.1 3.3 10.8 8.2 8.2 5.3 2.6 5.5 2.5 6.8 7.6 10.3 5.2 2.8 8.6 4.1 6.6 8.9 2.3 2.5 4.2 7.8 6.8 3.8 5.5 9.2 5.7 5.4 6.5 1.9 8.5 2.4 9.0 8.2 2.6 8.7 9.0 7.7 4.6 12.7 3.1 1.6 5.1 4.3 0.7 2.3 5.1 7.7 5.0 11.7 1.7 5.1 5.2 3.3 9.9 5.5 6.2 2.8 2.5 1.6 4.8 3.8 18.3 2.2 8.1 4.5 4.9 5.5 10.2 0.4 8.1 5.4 7.7 0.9 1.7 0.0 3.8 2.3 0.0 6.0 3.7 4.1 8.3 5.8 11.6 0.1 4.2 4.2 4.0 4.9 5.3 0.8 5.8 1.9 19.3 2.4 4.1 16.5 7.8 4.0 5.2 3.9 4.7 4.7 0.7 1.0 4.7 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 8.8 8.2 7.1 10.6 8.2 8.2 6.8 7.6 6.6 5.7 8.5 7.7 3.1 6.4 6.2 11.4 2.9 2.2 5.4 0.9 2.8 5.7 3.1 3.7 8.2 0.0 6.0 5.5 2.1 0.8 2.8 1.1 0.0 1.4 1.3 4.8 4.3 4.3 0.0 2.1 11.4 1.1 0.3 4.4 3.6 2.7 0.0 3.2 6.8 1.4 0.8 10.1 10.3 1.9 2.0 0.8 0.3 7.8 5.3 1.3 0.0 60.0 1.6 3.6 1.0 9.5 8.2 0.5 0.6 7.2 0.6 3.5 0.5 1.4 3.0 1.6 19.7 6.5 5.5 0.4 0.7 1.8 0.9 0.3 2.9 3.9 2.9 2.4 PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 206.6;Leydig cells: 100.6;Melanocytes: 192.1;Muller glia cells: 152.4;Peritubular cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 18.0;BJ: 7.7;fHDF/TERT166: 11.7;SuSa: 5.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" 114.8 23.4 12.6 4.2 14.2 0.5 77.5 7.7 20.2 126.7 20.0 136.4 6.6 147.7 7.6 41.3 108.6 40.4 212.0 11.6 10.0 25.3 15.6 124.7 8.0 10.2 8.2 128.2 13.1 2.5 22.6 12.0 9.4 73.6 8.9 21.5 32.7 77.1 35.6 56.4 61.0 51.4 8.3 44.2 41.3 7.2 10.3 3.2 60.4 36.9 15.9 147.8 92.9 9.4 0.2 0.2 0.5 0.1 18.0 0.5 0.4 7.7 1.0 0.2 0.2 0.0 0.1 1.2 0.6 11.7 0.1 0.6 0.2 0.3 0.3 0.0 0.1 0.2 0.5 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.2 2.1 0.0 0.4 0.2 0.4 1.3 0.1 0.1 0.5 0.4 0.3 0.1 0.4 0.2 0.4 0.0 0.3 1.0 0.2 0.2 0.2 0.8 5.2 0.2 0.1 0.6 0.5 0.2 0.3 0.1 0.2 0.3 1.2 0.1 0.2 0.5 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 12.6 14.2 7.7 20.2 11.6 10.0 10.2 8.2 9.4 8.3 10.3 9.4 8.8 0.0 5.8 5.2 0.9 18.2 1.0 0.0 2.2 3.6 4.2 5.1 7.4 1.5 0.6 0.0 2.1 0.1 0.3 0.1 0.0 0.0 1.1 0.6 1.7 15.6 0.0 2.7 1.6 0.0 0.1 206.6 4.6 1.6 5.1 0.2 22.9 0.3 0.3 1.7 0.2 0.0 0.0 0.3 19.2 5.3 100.6 0.9 192.1 22.5 0.0 152.4 0.0 7.5 0.5 0.0 0.0 199.7 0.4 0.6 0.0 0.1 1.5 8.9 26.3 9.6 38.3 3.1 2.4 1.6 9.9 0.3 1.6 0.1 0.0 1.3 PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 93.2;liver: 185.7" "Group enriched" "Detected in some" 15 "Fibroblasts: 320.6;Hepatocytes: 364.7" "Cancer enriched" "Detected in many" 10 "liver cancer: 28.4" "Region enriched" "Detected in single" 33 "hypothalamus: 30.8" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cell line enriched" "Detected in some" 6 "ASC diff: 284.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" NA NA 4300000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB054258: " "unprognostic (8.67e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-3)" "unprognostic (1.98e-1)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (4.11e-1)" "unprognostic (1.91e-13)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (1.60e-3)" "unprognostic (7.05e-3)" 93.2 2.3 0.0 2.3 0.0 0.3 15.1 0.4 0.9 0.6 3.9 1.2 0.0 0.6 0.9 0.3 20.0 0.4 31.7 0.0 30.8 0.2 185.7 26.4 0.4 0.0 0.0 2.1 1.5 0.0 2.1 0.0 0.1 0.6 0.1 0.1 3.9 0.1 9.5 7.7 0.4 0.3 0.2 0.7 1.4 0.2 0.2 0.3 1.7 8.1 0.3 2.6 0.5 0.0 0.0 0.1 0.0 0.0 284.6 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 1.1 0.1 0.2 0.2 0.0 26.2 0.0 44.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.7 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.9 0.0 30.8 0.0 0.0 0.1 0.2 0.2 0.0 5.1 22.4 16.2 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 2.7 10.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 3.7 4.1 0.0 2.7 0.0 0.0 0.0 320.6 0.0 0.8 16.4 0.0 6.4 364.7 0.1 0.0 0.1 0.0 0.0 9.4 1.9 0.8 0.0 2.8 1.8 0.0 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 0.1 0.0 0.0 10.9 0.0 0.0 3.5 1.5 0.0 0.3 0.0 1.1 0.0 2.3 0.1 0.0 0.1 PROCR "CCD41, CD201, EPCR" ENSG00000101000 "Protein C receptor" Q9UNN8 20 35172072-35216240 "Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 126.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 114.2;Fibroblasts: 83.4;granulocytes: 63.1;Hepatic stellate cells: 74.6;Sertoli cells: 170.9;Syncytiotrophoblasts: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 385.0;HUVEC TERT2: 611.1;TIME: 365.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 8.9" HPA039461 Enhanced NA NA 980000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA039461: AB_10673359" "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (4.69e-2)" "unprognostic (4.69e-2)" "unprognostic (1.84e-1)" "unprognostic (1.52e-1)" "unprognostic (4.76e-2)" "unprognostic (5.22e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (7.62e-6)" "unprognostic (3.37e-2)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.19e-2)" 126.8 23.1 6.8 19.6 7.3 8.6 53.9 12.0 7.7 31.2 14.6 25.2 16.3 36.2 13.4 12.0 42.9 21.2 43.5 7.0 6.8 15.6 6.8 19.8 10.0 8.9 7.3 18.0 12.6 6.1 8.6 31.3 8.8 19.5 21.4 1.8 8.7 17.3 10.1 25.2 21.4 28.4 7.5 27.5 23.2 5.0 8.9 3.0 26.0 10.3 4.0 34.2 28.4 10.1 15.2 88.9 0.2 9.2 93.6 76.1 20.2 20.8 90.4 33.7 65.2 115.2 76.7 2.9 63.3 21.0 93.6 48.5 20.2 131.8 27.8 0.7 27.5 33.2 19.8 4.7 22.8 1.3 385.0 65.1 48.8 159.0 131.1 49.2 611.1 1.1 11.8 4.2 35.3 5.0 1.1 1.6 12.2 18.8 90.4 0.6 16.7 0.4 58.3 5.8 2.7 1.2 11.3 23.9 18.8 11.0 8.1 5.0 365.5 86.0 43.2 32.8 35.4 0.3 1.1 0.9 99.1 33.5 18.6 5.0 1.5 0.8 8.2 1.8 14.8 0.9 2.5 5.2 7.8 1.3 0.6 5.9 4.0 3.3 1.3 1.3 2.2 2.2 6.8 7.3 12.0 7.7 7.0 6.8 8.9 7.3 8.8 7.5 8.9 10.1 19.9 0.0 12.6 2.3 0.5 13.9 18.5 10.1 10.2 0.5 1.1 4.4 2.4 5.7 4.9 5.5 0.0 12.1 2.0 0.5 1.9 32.2 1.6 1.0 24.0 58.8 6.0 2.7 3.6 16.4 114.2 83.4 1.5 0.9 63.1 15.9 74.6 1.9 21.9 1.7 2.5 0.7 0.0 1.6 8.8 1.0 15.5 13.5 3.6 9.4 2.2 0.3 7.2 0.5 5.6 15.6 0.5 2.6 0.6 9.7 9.8 6.3 1.8 0.6 170.9 4.3 45.9 20.4 19.7 2.8 8.4 69.0 4.4 4.2 2.0 11.9 PRRG3 TMG3 ENSG00000130032 "Proline rich and Gla domain 3" Q9BZD7 X 151694607-151705924 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.4;epididymis: 7.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.4;Excitatory neurons: 12.7;Fibroblasts: 15.2;Inhibitory neurons: 8.9;Langerhans cells: 22.4;Suprabasal keratinocytes: 22.6" "Cancer enhanced" "Detected in some" "stomach cancer: 1.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 1.0;SuSa: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060566 Uncertain NA NA "Cluster 42: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA060566: AB_2684321" "unprognostic (1.85e-1)" "unprognostic (1.21e-1)" "unprognostic (7.71e-2)" "unprognostic (1.77e-2)" "unprognostic (4.42e-4)" "unprognostic (7.24e-2)" "unprognostic (2.29e-2)" "unprognostic (1.28e-1)" "unprognostic (2.06e-2)" "unprognostic (5.11e-2)" "unprognostic (3.01e-2)" "unprognostic (2.26e-1)" "unprognostic (1.98e-2)" "unprognostic (7.69e-2)" "unprognostic (4.64e-2)" "unprognostic (1.57e-1)" "unprognostic (1.84e-2)" 1.9 0.2 9.5 0.2 9.1 0.2 1.8 0.0 11.4 5.3 0.2 1.2 0.1 1.7 7.4 2.3 0.9 2.0 2.0 7.8 7.1 0.5 0.0 1.2 0.1 1.6 2.1 2.1 0.1 0.2 1.5 0.8 4.0 0.6 0.6 0.7 1.7 0.2 2.3 1.5 0.4 1.4 0.2 1.7 0.6 0.3 8.6 1.2 0.9 1.9 0.2 1.1 2.7 7.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.2 0.3 0.2 0.2 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.2 0.6 0.5 0.4 0.3 0.2 0.2 9.5 9.1 0.0 11.4 7.8 7.1 1.6 2.1 4.0 0.2 8.6 7.2 7.4 0.0 0.0 0.7 0.1 18.4 0.4 0.0 2.8 0.1 0.6 1.7 4.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 3.9 0.0 0.0 0.2 0.7 5.7 0.0 0.0 12.7 0.0 0.0 15.2 0.0 0.5 0.0 0.5 1.4 0.2 0.1 0.0 8.9 0.0 0.0 0.0 22.4 0.0 0.3 0.3 7.2 1.0 0.0 0.1 0.0 1.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.3 0.0 3.1 2.1 0.0 0.1 0.2 22.6 0.0 1.3 0.3 0.0 0.3 PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 351.7;Endometrial stromal cells: 158.6;Fibroblasts: 180.2;Late spermatids: 390.0;Leydig cells: 256.3;Oligodendrocyte precursor cells: 288.5;Smooth muscle cells: 206.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 367.0;ASC TERT1: 290.5;BJ: 109.7;BJ hTERT+: 213.2;HSkMC: 150.6;U-138 MG: 146.0;U-2197: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" 96.3 10.2 14.5 17.7 15.2 0.0 42.9 15.4 13.4 92.0 5.4 5.6 1.1 68.6 20.3 20.1 42.3 34.1 44.2 12.6 26.2 2.3 0.4 21.7 34.6 17.4 18.5 28.2 3.8 7.5 4.9 6.3 16.8 33.5 5.7 0.1 38.5 75.6 51.7 24.1 3.6 52.4 7.9 1.9 3.4 14.2 16.5 18.7 41.6 73.9 36.3 33.0 58.8 15.0 0.0 0.0 2.1 0.0 367.0 290.5 0.1 109.7 213.2 15.0 14.8 0.0 0.1 0.1 0.0 90.2 0.0 0.0 18.5 0.0 4.7 0.0 0.2 0.0 1.6 0.0 1.2 0.0 0.0 150.6 0.0 73.4 0.4 25.7 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.0 0.0 0.1 146.0 2.6 140.4 16.9 0.0 0.0 0.0 77.3 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 15.2 15.4 13.4 12.6 26.2 17.4 18.5 16.8 7.9 16.5 15.0 49.8 0.0 0.5 114.3 0.3 16.3 0.6 0.1 4.0 0.0 1.3 10.2 29.8 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.2 351.7 4.9 158.6 11.4 0.0 0.0 17.4 0.2 0.1 180.2 0.5 3.5 0.0 0.6 0.0 0.0 0.8 0.0 5.5 0.0 0.0 0.0 27.9 390.0 256.3 2.8 14.2 124.6 0.0 0.5 0.0 288.5 0.9 0.7 0.0 104.6 0.4 1.7 0.0 0.1 0.0 0.2 52.6 59.1 206.5 15.4 1.9 1.2 11.8 0.1 2.3 0.6 0.0 1.2 PRRX2 "PMX2, PRX2" ENSG00000167157 "Paired related homeobox 2" Q99811 9 129665647-129722674 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.3;skin 1: 25.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.4;Early spermatids: 78.7;Fibroblasts: 44.2;Langerhans cells: 28.0;Smooth muscle cells: 21.2;Suprabasal keratinocytes: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 12.9;BJ: 28.7;BJ hTERT+: 20.3;fHDF/TERT166: 41.6;U-2197: 34.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.3" "HPA006607, HPA026808" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA006607: AB_2667623, HPA026808: AB_10603228" "unprognostic (4.02e-2)" "unprognostic (5.17e-2)" "unprognostic (7.65e-3)" "unprognostic (4.47e-3)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (2.16e-2)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.22e-1)" "unprognostic (1.94e-10)" "unprognostic (6.66e-2)" "unprognostic (4.48e-1)" "unprognostic (2.65e-2)" "unprognostic (9.47e-3)" 14.2 2.4 0.5 1.2 0.5 0.0 11.7 0.4 0.7 23.3 1.0 2.2 0.2 3.9 0.2 5.4 3.4 1.3 9.5 0.6 1.2 1.2 0.1 4.6 1.1 0.5 0.5 1.3 0.9 0.5 4.5 1.4 0.6 14.1 0.3 0.0 7.5 2.7 1.6 25.5 1.6 0.6 0.4 0.1 2.8 10.7 0.5 0.3 9.5 0.6 0.8 10.7 18.3 0.5 0.0 0.7 0.0 1.1 3.3 12.9 0.1 28.7 20.3 3.6 4.0 0.0 0.0 0.0 10.2 41.6 1.5 0.3 0.8 0.0 0.3 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 1.1 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.6 0.0 0.0 4.4 2.1 6.4 0.0 0.0 0.0 0.9 0.0 0.0 2.7 1.3 0.1 0.0 1.4 2.7 0.5 0.0 0.0 8.3 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.7 0.6 1.2 0.5 0.5 0.6 0.4 0.5 0.5 3.9 0.0 0.0 0.7 0.1 27.4 1.1 16.0 0.6 0.0 6.0 6.0 0.3 0.0 10.1 0.0 0.0 0.2 0.1 0.0 1.9 0.1 78.7 1.0 6.3 3.0 0.0 0.0 0.4 0.0 0.4 44.2 0.5 1.8 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 2.0 0.0 28.0 10.2 2.8 0.3 8.8 0.0 0.0 0.0 0.0 5.0 0.1 0.9 0.0 3.4 0.0 4.0 0.0 0.1 7.9 0.0 0.0 0.4 21.2 3.6 6.8 0.5 29.7 0.4 0.8 0.0 0.0 6.2 PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 20.1" "Cell type enhanced" "Detected in many" "Club cells: 14.3;Fibroblasts: 22.7;Inhibitory neurons: 10.4;Langerhans cells: 10.6;Microglial cells: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "ASC TERT1: 271.2;HSkMC: 85.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.89e-3)" "unprognostic (6.03e-2)" "unprognostic (5.63e-2)" "unprognostic (1.45e-3)" "unprognostic (7.61e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "unprognostic (8.46e-4)" "unprognostic (2.21e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-4)" "unprognostic (3.21e-4)" "unprognostic (8.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.21e-3)" 9.9 3.4 0.6 5.7 0.4 0.0 7.2 0.1 1.8 4.6 0.3 2.0 1.0 17.9 2.4 0.9 4.6 6.9 1.7 1.9 2.7 3.9 1.3 2.5 1.2 0.7 0.5 4.6 0.9 0.0 0.2 8.1 1.8 3.1 2.7 0.2 4.7 2.0 2.1 5.2 2.4 16.7 0.4 0.6 1.6 1.4 3.5 0.1 0.8 20.1 4.3 11.9 4.4 0.2 0.0 0.0 1.0 0.0 26.5 271.2 0.0 20.5 20.0 7.0 2.7 0.0 0.0 0.0 0.0 12.4 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 85.7 0.0 1.8 17.6 18.3 0.1 0.0 0.0 0.7 10.9 0.0 0.0 0.0 0.1 0.0 15.9 0.0 0.0 0.0 2.4 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 5.9 8.5 4.7 2.1 1.6 1.1 0.0 0.0 0.5 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 1.8 1.9 2.7 0.7 0.5 1.8 0.4 3.5 0.2 1.2 0.0 8.0 0.3 0.0 6.4 0.0 1.0 0.0 1.2 0.2 0.0 0.4 5.7 14.3 9.2 0.0 0.1 0.0 0.0 3.9 4.2 8.5 0.4 0.6 0.6 0.0 0.0 0.4 0.0 0.0 22.7 0.5 0.1 0.0 0.1 0.0 2.3 0.1 0.0 10.4 0.0 0.0 0.0 10.6 9.3 5.6 0.4 5.4 17.8 0.0 0.3 0.0 0.0 0.2 0.0 1.1 0.4 0.2 0.1 0.0 0.3 6.3 0.0 6.6 7.1 1.4 1.1 0.2 0.1 4.7 0.3 0.5 0.3 0.0 0.0 PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568137 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 80.7;urinary bladder: 81.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 28.1;Fibroblasts: 70.8;Hepatic stellate cells: 117.8;Leydig cells: 26.8;Peritubular cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 45.1;ASC TERT1: 45.2;U-2197: 143.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB009517: AB_2173209, HPA014193: AB_1855746, HPA052244: AB_2732574" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (5.09e-3)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.45e-2)" "unprognostic (5.22e-2)" "prognostic unfavorable (4.74e-8)" "unprognostic (2.29e-2)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "prognostic unfavorable (9.99e-5)" 43.2 4.7 0.7 9.0 2.5 0.3 24.0 0.3 1.9 29.5 1.8 38.9 3.2 79.0 16.1 16.5 80.7 31.3 40.4 0.5 0.8 4.0 6.0 18.2 0.7 0.6 0.4 38.1 2.5 0.3 0.9 1.1 0.4 22.2 6.6 0.2 7.6 8.3 4.0 7.2 10.5 40.5 0.6 0.5 17.9 5.1 1.0 0.3 7.8 2.4 0.8 81.7 18.2 0.6 0.0 0.1 1.9 0.1 45.1 45.2 0.5 1.0 5.7 0.2 0.0 0.0 0.0 0.1 18.4 13.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.1 3.3 0.0 0.6 0.0 15.1 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.2 8.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.2 0.0 8.2 0.1 0.0 0.0 0.8 2.4 143.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.7 2.5 0.3 1.9 0.5 0.8 0.6 0.4 0.4 0.6 1.0 0.6 5.3 3.2 2.7 0.0 0.0 3.7 0.7 0.0 0.0 1.1 2.2 1.3 5.0 2.8 1.9 3.7 0.0 0.3 0.3 0.0 0.0 0.6 1.8 0.0 0.9 28.1 0.0 2.7 2.7 0.0 0.2 70.8 1.5 0.1 0.0 25.0 117.8 1.0 0.3 0.0 2.4 0.0 0.0 3.1 6.7 3.3 26.8 1.0 1.8 6.5 0.1 0.4 0.0 1.0 0.2 1.2 0.0 104.9 0.3 0.4 0.0 0.2 2.2 4.5 0.0 7.9 3.5 0.7 1.4 0.5 4.8 0.3 1.0 0.5 0.0 0.6 PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase non-receptor type 9" P43378 15 75463251-75579315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 63.0;Excitatory neurons: 66.1;Inhibitory neurons: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041922: AB_10795269" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" "unprognostic (3.14e-1)" "unprognostic (9.25e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.49e-6)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" 15.9 12.0 14.8 13.0 16.3 10.8 15.1 11.9 18.8 16.6 11.7 18.0 17.9 16.5 13.3 9.9 16.2 12.1 11.0 16.9 18.4 18.2 14.7 15.8 14.5 18.6 14.4 14.0 10.2 17.9 9.7 19.9 15.1 16.6 19.7 8.9 13.0 21.2 6.4 11.0 20.0 18.0 13.6 13.4 13.5 7.2 17.0 16.1 32.8 13.1 15.0 18.1 13.8 14.5 20.3 24.1 36.7 24.6 26.8 29.3 12.0 29.8 46.2 36.9 33.4 14.5 30.0 32.6 23.3 51.1 29.5 30.0 79.9 34.3 37.0 40.5 19.8 18.4 16.2 15.7 40.2 28.2 27.1 38.4 35.2 29.6 45.9 37.7 31.4 21.3 12.4 11.5 42.1 13.5 20.0 26.3 33.6 18.2 12.1 38.9 18.2 9.1 46.6 32.5 14.4 29.9 42.4 23.3 46.3 34.9 12.1 47.8 36.5 35.2 11.3 23.3 32.2 16.9 18.9 30.0 20.5 41.9 35.3 3.2 2.2 2.3 3.4 3.0 2.8 1.7 2.4 3.0 3.0 1.3 1.0 1.8 0.3 3.9 2.9 2.0 1.6 1.7 14.8 16.3 11.9 18.8 16.9 18.4 18.6 14.4 15.1 13.6 17.0 14.5 12.7 6.4 13.4 63.0 9.2 3.3 8.2 6.6 5.7 12.1 8.0 7.1 3.7 10.0 8.1 11.0 8.4 20.0 7.3 25.0 15.6 10.8 3.0 7.9 19.4 10.0 7.2 13.7 66.1 9.9 4.2 20.6 10.7 11.4 15.2 23.6 17.5 12.6 18.8 3.3 63.2 11.5 6.1 18.9 18.1 4.7 12.5 16.5 7.2 46.9 24.2 5.6 19.6 48.7 19.6 18.2 12.6 27.4 9.7 12.1 24.9 14.0 8.1 17.1 13.1 11.7 20.8 10.6 9.4 6.6 3.3 10.1 13.4 11.6 13.2 13.1 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase receptor type A" P18433 20 2864184-3039076 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: AB_2686141" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favorable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 48.8 36.6 83.9 31.9 89.3 39.6 47.4 84.2 96.1 56.4 59.5 41.6 31.0 53.0 36.7 46.1 52.7 43.7 29.5 87.7 83.5 44.2 28.6 45.4 38.9 74.7 81.9 55.8 31.2 81.9 44.8 60.8 78.3 46.3 40.6 61.5 36.3 41.9 16.9 45.8 32.7 52.4 76.3 39.4 34.5 43.4 92.6 59.6 65.5 30.7 44.3 46.6 38.9 81.1 74.0 44.2 124.7 38.4 134.4 243.3 26.5 54.1 105.1 65.5 79.6 53.1 99.5 48.1 41.6 73.1 66.1 77.2 51.0 77.4 73.4 74.7 32.7 68.5 18.3 68.0 48.1 69.5 31.1 109.8 78.2 54.4 56.8 80.3 92.0 67.7 69.9 59.7 65.8 30.4 80.8 78.3 48.3 66.0 35.0 61.0 60.5 60.3 55.1 56.2 68.7 65.7 52.3 87.8 81.4 54.0 55.2 58.7 66.5 58.1 28.6 65.6 48.5 43.4 64.7 62.7 26.9 64.5 55.7 5.7 2.8 4.8 6.1 2.9 4.9 5.3 4.0 4.4 2.1 2.6 4.0 4.8 3.3 4.0 4.3 3.2 4.9 2.3 83.9 89.3 84.2 96.1 87.7 83.5 74.7 81.9 78.3 76.3 92.6 81.1 87.0 22.4 19.2 128.6 46.7 15.8 34.0 15.0 34.7 88.9 49.0 43.9 10.1 54.3 24.5 46.0 31.3 35.3 111.7 39.8 27.4 14.8 17.0 62.0 109.0 39.7 44.3 42.3 138.2 15.8 40.5 67.5 25.0 55.3 22.9 60.3 43.5 33.6 39.4 70.7 136.4 27.9 24.4 37.6 20.4 17.2 60.3 40.1 37.4 52.5 29.9 88.3 110.2 102.5 147.5 16.6 30.2 48.9 58.6 32.9 27.1 23.6 26.6 60.5 39.5 53.3 61.8 68.7 84.1 32.9 17.2 32.7 59.7 41.4 30.4 31.5 PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.8;Inhibitory neurons: 104.2;Melanocytes: 80.0;Oligodendrocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "plasmacytoid DC: 12.5" "Lineage enriched" "Detected in single" 89 "dendritic cells: 12.5" "Cell line enhanced" "Detected in many" "AN3-CA: 121.8;HaCaT: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 150000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 54.7 21.2 34.4 5.0 25.5 1.5 36.2 3.2 30.9 40.2 0.0 25.2 2.6 30.5 2.2 16.5 41.1 13.7 37.0 34.3 10.0 11.2 6.0 26.9 5.5 16.4 16.4 35.8 32.4 9.7 29.1 2.3 17.6 30.5 1.6 5.7 18.6 14.6 14.4 20.6 13.6 8.6 1.6 9.0 23.2 9.9 27.3 4.2 29.4 7.4 4.4 32.0 31.8 34.9 11.3 64.0 56.2 121.8 25.3 20.5 7.4 19.4 22.5 22.8 18.5 0.7 6.2 0.2 44.5 32.2 18.0 124.6 15.1 0.2 10.0 1.5 24.3 0.0 27.2 40.5 11.7 0.0 14.1 21.8 5.4 4.8 0.9 29.4 0.6 7.9 18.5 0.2 9.1 48.0 5.2 12.3 31.7 0.4 27.0 0.0 12.4 0.0 4.7 22.5 43.1 58.9 18.3 3.4 34.6 10.7 22.0 4.8 2.8 20.2 34.3 46.9 23.6 6.2 0.1 36.9 10.5 0.0 44.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 34.4 25.5 3.2 30.9 34.3 10.0 16.4 16.4 17.6 1.6 27.3 34.9 1.1 6.4 1.1 53.8 3.2 60.9 42.4 16.1 22.2 49.6 3.3 5.5 14.1 27.1 4.9 12.9 2.1 0.7 56.4 0.1 9.8 1.4 3.4 5.4 11.4 9.7 3.0 0.0 76.8 0.9 32.2 51.2 5.1 5.3 0.0 4.0 25.4 20.2 1.7 11.8 104.2 0.0 10.2 0.3 20.0 5.4 46.6 3.4 80.0 15.9 0.8 46.6 0.0 71.9 90.2 0.5 0.0 36.1 6.3 35.0 0.0 2.9 1.7 10.1 13.1 46.4 22.6 7.4 14.8 16.8 36.7 1.0 2.0 2.7 0.4 30.0 PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 231.5;urinary bladder: 191.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 16.2;Fibroblasts: 44.7;Glandular and luminal cells: 24.0;Langerhans cells: 23.6;Macrophages: 27.0;Melanocytes: 14.2" "Cancer enhanced" "Detected in many" "glioma: 22.5" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.9;thalamus: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1219.3;ASC TERT1: 1751.7;BJ hTERT+: 1201.8;HHSteC: 2261.1;HSkMC: 2364.2;hTEC/SVTERT24-B: 1276.5;TIME: 1761.1;U-2197: 1605.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Approved "Plasma membrane" "Secreted to blood" NA NA 1090000 970000 "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA069320: AB_2686118" "unprognostic (1.93e-2)" "unprognostic (4.96e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (8.35e-9)" "unprognostic (5.79e-3)" "prognostic unfavorable (6.36e-4)" "unprognostic (6.03e-3)" "prognostic unfavorable (8.75e-6)" "unprognostic (2.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.60e-2)" "unprognostic (2.63e-1)" "unprognostic (2.76e-9)" "unprognostic (6.03e-3)" "unprognostic (5.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.92e-3)" 231.5 11.1 0.4 38.8 0.4 89.0 57.9 0.6 1.9 2.8 1.1 13.0 0.8 2.5 0.5 2.9 21.4 7.7 46.8 0.6 0.5 6.8 2.6 83.2 0.9 0.7 0.6 1.4 41.6 1.1 4.4 11.4 0.6 6.9 2.3 0.4 5.4 0.5 5.2 25.4 9.7 5.7 0.3 23.6 24.8 0.7 4.0 1.6 5.8 0.5 0.3 191.7 3.1 0.4 1.2 0.0 752.4 0.2 1219.3 1751.7 0.3 132.3 1201.8 56.2 60.9 0.7 7.9 0.2 460.6 157.4 87.6 0.0 0.3 1.1 110.5 0.8 0.3 2.0 0.1 0.0 2261.1 2.5 0.0 2364.2 0.8 1276.5 429.8 110.2 266.4 0.1 0.3 0.0 380.1 0.0 0.3 2.9 11.2 0.0 4.6 0.2 0.0 0.2 5.3 53.1 6.0 0.8 7.6 1.0 0.9 0.1 0.6 2.4 1761.1 252.2 12.2 1605.1 23.0 0.2 0.5 0.9 52.8 6.4 74.2 0.0 0.3 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 1.9 0.6 0.5 0.7 0.6 0.6 0.3 4.0 0.4 2.3 0.0 1.7 0.0 0.1 1.7 1.7 0.3 0.0 1.8 3.6 0.6 0.6 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 7.2 2.4 16.2 10.3 5.1 0.0 0.0 0.5 0.0 0.1 44.7 0.0 24.0 0.0 0.7 3.3 0.0 2.6 0.0 1.0 0.0 0.0 10.0 23.6 1.2 0.3 27.0 14.2 0.0 2.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.8 0.0 4.0 7.2 0.0 0.4 0.4 1.0 0.3 0.4 0.0 0.0 0.4 PXDC1 C6orf145 ENSG00000168994 "PX domain containing 1" Q5TGL8 6 3722614-3751713 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.6;Basal prostatic cells: 115.1;Extravillous trophoblasts: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "HHSteC: 151.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019246 Approved "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA019246: AB_2670113" "unprognostic (1.55e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (3.64e-4)" "prognostic unfavorable (1.14e-4)" "unprognostic (2.82e-2)" "unprognostic (3.80e-2)" "unprognostic (2.95e-1)" "unprognostic (1.48e-1)" "unprognostic (6.73e-2)" "unprognostic (6.08e-2)" "unprognostic (2.32e-1)" "unprognostic (2.13e-1)" "unprognostic (2.01e-2)" "unprognostic (6.17e-3)" "unprognostic (1.10e-1)" "unprognostic (2.97e-1)" "unprognostic (2.84e-1)" 68.0 14.9 33.7 14.7 34.6 1.4 50.5 35.1 36.5 30.3 49.3 37.2 29.9 31.4 15.6 25.5 28.3 48.3 36.0 33.0 35.2 25.9 168.7 47.6 13.0 39.5 36.1 19.2 26.7 14.2 13.9 61.8 36.4 29.8 7.7 3.1 39.3 19.8 16.9 38.7 26.5 26.7 36.9 19.0 28.5 5.6 35.7 7.4 44.6 15.6 6.7 46.3 28.7 36.0 44.5 17.5 28.6 19.9 87.9 66.4 99.4 75.6 57.7 62.6 48.2 30.6 8.8 0.0 49.0 123.9 48.0 34.4 5.7 20.8 29.3 43.2 6.6 0.0 14.7 26.8 151.4 0.1 0.2 59.0 67.2 38.8 83.2 52.7 70.2 3.0 0.1 5.9 49.7 2.7 0.1 0.5 1.3 9.0 27.3 2.5 16.0 2.1 24.4 35.7 3.1 1.6 51.7 52.4 115.5 38.3 4.6 2.7 77.8 56.9 24.7 22.2 54.4 0.1 0.1 0.2 13.6 0.1 40.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 33.7 34.6 35.1 36.5 33.0 35.2 39.5 36.1 36.4 36.9 35.7 36.0 103.6 48.1 8.6 8.1 8.1 48.3 115.1 11.8 40.9 0.6 28.0 27.7 8.1 18.6 11.7 7.3 0.0 32.8 1.5 0.6 11.7 33.2 0.5 4.7 18.3 39.6 0.0 5.3 0.1 51.6 131.0 62.1 14.8 5.6 3.8 1.6 45.7 68.7 25.1 0.0 2.6 1.4 8.2 9.7 80.8 0.9 22.7 31.6 24.9 9.4 22.0 16.0 0.0 11.1 2.5 77.6 0.1 18.0 4.4 55.8 25.7 20.4 9.6 0.8 0.0 38.7 33.4 0.6 4.5 17.5 33.1 78.4 3.2 0.4 1.2 47.4 RAB11FIP2 "KIAA0941, nRip11, Rab11-FIP2" ENSG00000107560 "RAB11 family interacting protein 2" Q7L804 10 118004916-118046941 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 82.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037726 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "HPA037726: AB_10672390" "unprognostic (1.97e-1)" "unprognostic (1.68e-2)" "unprognostic (3.61e-1)" "unprognostic (4.45e-2)" "unprognostic (1.30e-1)" "unprognostic (5.58e-2)" "unprognostic (2.17e-2)" "unprognostic (3.34e-2)" "unprognostic (1.83e-2)" "unprognostic (2.15e-1)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (9.69e-5)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (2.17e-1)" 8.6 6.6 5.2 6.6 7.0 13.8 6.9 4.8 8.5 10.2 2.4 8.2 3.6 18.8 28.5 6.3 11.8 8.3 6.1 7.1 3.4 12.2 5.4 7.6 6.9 2.8 4.6 9.9 5.6 6.3 4.3 8.2 2.2 10.8 4.9 10.3 4.8 24.7 5.0 5.9 5.5 19.5 3.7 6.6 17.2 7.8 5.3 6.2 11.4 7.5 5.5 7.6 6.2 6.1 7.1 8.8 7.3 9.3 11.9 15.0 7.8 13.8 15.8 8.3 8.6 7.4 7.4 14.5 10.8 14.0 6.1 4.8 10.1 6.1 12.8 3.8 10.9 5.1 9.1 5.1 17.2 9.7 5.5 14.8 11.3 11.6 25.4 11.0 5.1 9.3 3.9 12.1 10.9 2.5 7.5 7.3 6.2 3.1 6.2 6.4 26.0 4.9 12.4 5.6 1.7 13.5 9.8 3.9 17.3 8.7 3.0 8.9 7.7 11.2 8.9 13.3 13.8 8.9 7.8 9.4 11.5 16.4 7.0 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.4 0.4 0.2 0.3 0.1 0.1 0.5 0.1 0.0 5.2 7.0 4.8 8.5 7.1 3.4 2.8 4.6 2.2 3.7 5.3 6.1 16.7 57.7 31.5 79.7 17.7 10.3 8.8 4.4 12.5 28.1 10.1 10.7 25.8 24.3 6.0 42.3 29.2 11.6 15.1 5.5 7.9 12.6 16.5 13.1 31.0 14.1 14.5 17.4 63.8 18.7 7.9 29.1 14.8 15.7 3.8 28.0 11.4 8.6 11.4 38.7 57.9 6.6 4.1 23.0 12.2 6.6 33.5 16.2 23.2 34.7 19.4 26.0 15.5 53.8 82.9 16.6 4.7 28.6 17.0 11.1 5.4 18.1 7.3 31.4 26.3 34.0 25.8 14.9 21.2 9.2 9.5 5.2 12.9 19.2 6.5 6.4 RAB40AL "RAR2, RLGP" ENSG00000102128 "RAB40A like" P0C0E4 X 102937272-102938300 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.8;Cone photoreceptor cells: 2.1;Enteroendocrine cells: 3.0;Hepatic stellate cells: 2.2;Horizontal cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076172 Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA076172: " "unprognostic (1.99e-1)" "unprognostic (3.05e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-1)" "unprognostic (2.91e-1)" "unprognostic (1.39e-1)" "unprognostic (3.49e-1)" "unprognostic (1.83e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-2)" "unprognostic (5.90e-10)" "unprognostic (4.74e-1)" "unprognostic (1.32e-1)" "unprognostic (5.02e-3)" "unprognostic (2.64e-2)" 0.1 0.1 0.5 0.0 0.4 0.0 0.1 0.2 1.1 0.1 0.3 0.1 0.1 0.2 0.3 0.1 0.1 0.0 0.1 0.5 0.4 0.1 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.2 1.1 0.5 0.4 0.3 0.0 0.3 0.0 0.1 0.8 0.2 0.0 0.0 0.0 0.4 0.1 0.1 0.0 1.2 1.8 0.1 0.1 0.1 0.0 0.0 0.0 2.1 0.9 1.3 0.6 0.0 0.0 0.1 0.1 0.2 0.4 3.0 0.4 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.1 2.2 0.9 0.4 1.7 0.0 0.2 0.0 0.8 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 1.5 0.0 0.5 0.4 0.0 0.0 0.6 0.0 1.2 0.1 0.3 0.3 0.1 0.0 0.7 0.0 0.1 0.6 0.3 RAD50 "hRad50, RAD50-2" ENSG00000113522 "RAD50 double strand break repair protein" Q92878 5 132556019-132646349 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022103, CAB024979, HPA052291" Supported Supported Nucleoplasm NA NA 12000 "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB022103: , CAB024979: , HPA052291: AB_2681786" "unprognostic (3.46e-3)" "prognostic unfavorable (3.77e-4)" "unprognostic (7.50e-3)" "unprognostic (4.22e-3)" "unprognostic (6.71e-2)" "unprognostic (5.98e-2)" "unprognostic (2.76e-2)" "unprognostic (1.06e-1)" "unprognostic (6.84e-2)" "unprognostic (2.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.62e-1)" "prognostic favorable (1.95e-4)" "unprognostic (1.86e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-2)" "unprognostic (2.40e-1)" 6.3 8.0 5.8 2.8 6.9 5.9 6.6 7.6 8.6 6.9 4.0 8.7 2.5 8.1 10.3 7.6 7.3 3.5 7.1 6.8 4.9 6.1 6.2 5.0 2.5 5.0 4.4 9.2 9.2 8.8 8.1 3.6 5.7 6.2 4.6 8.5 7.1 4.2 11.3 10.4 8.0 3.8 3.4 5.4 8.6 5.5 5.4 4.0 6.0 4.7 3.5 7.9 6.9 8.6 9.1 22.8 2.1 12.1 13.3 20.0 9.8 6.3 11.2 11.0 12.8 20.4 14.8 20.6 3.7 10.3 19.7 8.8 17.6 14.2 16.5 11.7 13.4 9.5 13.3 12.5 10.8 10.2 7.6 10.8 24.1 13.4 36.7 7.2 5.4 6.5 17.9 3.2 10.1 8.6 7.7 13.9 11.7 9.0 6.8 7.2 3.7 10.1 8.8 16.9 11.5 14.9 11.7 4.7 2.8 5.6 11.5 7.0 9.5 4.7 5.5 14.5 8.3 5.7 7.7 24.2 8.4 12.5 6.7 7.0 3.3 1.1 4.1 3.8 5.6 7.0 5.4 5.4 3.6 5.8 4.9 4.5 0.3 9.3 4.8 2.5 4.0 2.7 5.8 6.9 7.6 8.6 6.8 4.9 5.0 4.4 5.7 3.4 5.4 8.6 3.5 38.5 27.1 65.6 34.6 26.0 37.3 33.7 31.9 56.8 6.6 4.8 130.0 44.3 31.6 7.3 89.6 69.6 22.9 31.0 1.9 6.3 26.4 8.2 15.8 16.6 37.1 38.5 65.9 6.0 49.2 37.6 37.2 7.6 30.4 8.5 22.1 38.5 37.4 37.0 79.7 44.1 18.3 27.2 12.2 12.6 60.6 16.5 16.0 49.6 22.4 38.0 48.4 65.9 92.4 4.8 35.6 53.4 33.0 32.1 53.7 4.4 40.8 60.8 32.9 50.9 39.9 108.4 87.2 39.2 26.7 33.1 25.2 11.5 52.3 25.1 RAPSN "CMS1D, CMS1E, RNF205" ENSG00000165917 "Receptor associated protein of the synapse" Q13702 11 47437764-47449143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 88.9;tongue: 33.1" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 63.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 238.7" "Low region specificity" "Detected in some" HPA039475 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Centrosome, Cytosol" "HPA039475: AB_10794196" "unprognostic (5.37e-2)" "unprognostic (1.02e-1)" "unprognostic (7.34e-2)" "unprognostic (4.58e-2)" "unprognostic (2.95e-2)" "unprognostic (1.44e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-3)" "unprognostic (1.35e-1)" "unprognostic (5.38e-2)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.64e-4)" "unprognostic (3.83e-1)" "unprognostic (4.73e-3)" "unprognostic (4.48e-2)" 0.3 1.5 0.5 0.2 0.5 0.3 0.2 0.3 1.2 0.2 0.9 0.8 0.1 0.0 0.1 1.2 0.1 0.1 2.6 0.5 0.5 0.3 0.5 0.4 0.2 0.3 0.5 0.0 0.2 0.0 0.1 2.1 0.5 0.7 0.0 0.1 1.3 0.0 88.9 0.5 0.5 0.1 0.4 0.6 0.2 0.3 0.6 0.1 0.2 33.1 0.1 0.1 0.1 0.5 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.7 0.1 0.2 1.2 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 59.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 238.7 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.3 0.1 0.3 0.3 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 1.2 0.5 0.5 0.3 0.5 0.5 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.3 1.4 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.5 2.7 0.3 0.1 0.2 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.5 0.0 0.2 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.3 0.3 13.8 0.0 0.5 0.0 0.0 0.6 1.3 0.0 0.5 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 1.1 0.0 0.0 63.8 0.5 0.0 0.4 0.0 0.0 0.3 0.4 0.1 0.2 0.1 RASD1 "AGS1, DEXRAS1" ENSG00000108551 "Ras related dexamethasone induced 1" Q9Y272 17 17494437-17496395 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 371.9" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 425.1;Muller glia cells: 375.3;Peritubular cells: 469.8;Sertoli cells: 565.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 46 "plasmacytoid DC: 160.1" "Lineage enriched" "Detected in many" 46 "dendritic cells: 160.1" "Group enriched" "Detected in some" 4 "ASC diff: 70.2;REH: 71.0" "Group enriched" "Detected in all" 5 "basal ganglia: 75.6;hippocampal formation: 54.9;thalamus: 53.2" "Low region specificity" "Detected in all" HPA047896 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "HPA047896: AB_10960535" "unprognostic (1.59e-1)" "unprognostic (1.32e-1)" "unprognostic (3.28e-2)" "unprognostic (3.31e-2)" "unprognostic (6.40e-2)" "unprognostic (8.13e-2)" "unprognostic (8.65e-2)" "unprognostic (7.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.11e-1)" "unprognostic (3.17e-3)" "unprognostic (2.92e-1)" "unprognostic (7.40e-2)" "unprognostic (1.11e-2)" "unprognostic (1.38e-1)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" 244.7 53.5 48.7 5.9 63.7 9.3 153.3 31.1 83.6 69.2 13.4 16.1 5.4 22.8 11.9 11.7 32.7 12.6 91.0 60.8 61.9 181.7 271.3 25.4 3.0 71.6 49.8 53.7 30.1 4.2 371.9 1.3 39.4 32.7 6.5 47.7 97.8 55.7 183.1 44.1 12.2 3.4 45.7 18.6 42.2 47.7 40.4 13.1 88.4 103.0 1.2 16.6 26.3 53.6 0.0 0.3 0.3 0.0 70.2 3.8 0.3 0.9 1.4 0.1 0.2 3.0 0.0 0.0 8.0 0.3 0.0 0.2 0.3 0.0 0.1 0.1 0.9 0.3 0.3 8.3 0.5 0.1 0.3 17.1 0.0 0.7 0.0 0.0 0.3 0.2 0.0 0.0 0.2 7.5 13.8 1.3 1.4 1.3 4.5 71.0 0.1 0.1 1.5 0.0 12.9 0.4 1.1 0.9 16.3 2.1 0.1 0.1 4.1 0.1 0.7 0.5 0.2 14.5 0.6 0.2 0.4 0.0 0.5 0.0 0.4 0.0 0.4 3.5 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.8 160.1 0.1 1.0 48.7 63.7 31.1 83.6 60.8 61.9 71.6 49.8 39.4 45.7 40.4 53.6 172.2 28.9 36.8 21.2 11.0 17.2 96.2 46.6 27.3 51.4 106.9 147.2 71.2 20.0 33.5 149.0 4.2 3.3 45.8 42.9 13.7 93.5 2.7 150.9 264.2 31.1 222.4 0.4 15.0 1.3 2.2 191.1 86.6 425.1 8.8 40.3 9.7 21.6 3.6 6.7 5.2 262.7 260.4 3.1 22.2 8.1 109.6 27.3 30.2 1.9 2.2 375.3 0.0 17.1 1.6 9.0 21.8 469.8 56.1 73.3 16.8 13.8 7.2 23.8 565.4 228.1 191.7 1.7 3.0 54.8 13.2 6.7 27.0 73.7 32.9 20.0 RBM43 "C2orf38, FLJ45645" ENSG00000184898 "RNA binding motif protein 43" Q6ZSC3 2 151247940-151261863 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 20.4;HSkMC: 18.5" "Low region specificity" "Detected in all" HPA038204 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA038204: AB_10669520" "unprognostic (3.50e-2)" "unprognostic (5.45e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-1)" "unprognostic (1.12e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (9.72e-3)" "unprognostic (2.57e-2)" "unprognostic (3.43e-3)" "unprognostic (1.22e-2)" "unprognostic (3.07e-2)" "unprognostic (1.12e-2)" "unprognostic (9.94e-2)" 5.2 8.7 2.4 4.2 2.3 6.7 6.9 1.6 2.3 7.5 3.5 4.2 3.0 7.6 9.4 3.2 12.3 6.8 3.2 2.1 2.7 7.0 6.7 6.1 6.9 2.9 2.9 15.4 4.0 5.1 2.9 5.7 2.3 6.5 4.4 1.8 5.2 7.7 3.4 4.7 3.9 5.7 2.8 7.9 4.6 3.6 2.9 7.0 12.3 2.5 4.7 3.8 3.1 3.0 3.5 2.2 3.5 4.7 9.4 20.4 2.3 4.0 9.2 5.0 7.2 0.1 5.7 2.7 1.5 7.3 2.7 1.7 1.1 4.6 2.5 4.2 2.5 6.6 1.0 0.2 9.1 8.2 2.2 18.5 5.0 4.0 3.0 7.4 10.7 2.9 2.7 3.0 6.8 3.5 4.7 3.9 1.3 0.1 4.2 3.2 4.1 1.6 8.4 3.0 1.3 4.2 3.8 2.8 7.8 0.6 4.1 5.2 6.1 3.7 3.3 3.2 1.7 1.1 0.8 0.0 9.7 3.3 2.3 1.0 0.7 3.0 1.2 0.9 2.0 1.2 1.6 1.5 0.5 1.3 2.0 1.5 0.8 2.7 2.4 0.2 0.8 0.6 2.4 2.3 1.6 2.3 2.1 2.7 2.9 2.9 2.3 2.8 2.9 3.0 26.5 3.2 8.9 2.9 9.6 3.3 3.2 5.8 5.7 6.7 8.6 14.9 2.6 11.5 5.7 18.4 0.0 6.8 8.4 1.7 27.4 6.8 3.0 30.9 17.2 16.9 6.1 8.8 1.0 5.9 4.7 21.8 5.6 9.4 3.8 13.4 20.7 9.1 5.1 6.7 1.3 6.9 4.1 10.4 4.3 2.4 28.0 8.2 3.6 2.8 12.3 22.1 13.4 4.0 0.9 4.6 5.6 29.0 5.5 2.8 5.5 18.2 26.3 1.3 0.0 18.4 13.0 0.5 3.6 7.3 3.1 1.4 13.5 30.4 3.7 2.2 RBMS1 "C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1" ENSG00000153250 "RNA binding motif single stranded interacting protein 1" P29558 2 160272151-160493807 "Predicted intracellular proteins" "DNA replication" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 398.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047943, HPA061791" Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA047943: AB_2797235, HPA061791: AB_2684611" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (3.78e-2)" "unprognostic (1.38e-3)" "unprognostic (2.50e-1)" "unprognostic (6.81e-3)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (7.16e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (1.33e-7)" "unprognostic (1.84e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (2.32e-1)" 58.2 22.6 8.7 43.3 13.3 35.8 34.5 9.7 11.9 36.6 17.2 38.9 12.8 51.7 12.6 28.9 31.6 34.1 41.0 7.2 10.7 36.5 22.3 47.7 28.3 13.8 12.3 44.1 10.2 50.4 16.0 83.8 15.0 24.0 15.8 6.8 19.2 28.6 16.4 29.4 20.5 56.9 10.9 40.7 20.1 10.4 13.4 26.1 23.0 23.8 22.0 57.0 31.6 10.2 50.5 18.2 63.9 8.4 90.2 155.6 77.1 62.7 89.1 42.4 43.8 50.9 36.9 0.4 76.3 106.6 20.0 30.0 31.1 46.0 69.2 40.9 23.2 18.9 44.2 41.0 82.3 30.8 1.1 187.9 35.6 73.7 32.8 56.7 67.5 15.1 1.2 23.0 103.2 39.4 28.8 31.2 39.3 8.3 40.1 21.6 55.7 25.5 64.9 61.1 8.3 21.7 39.1 22.9 60.2 78.8 11.7 47.9 81.7 75.3 47.7 69.7 57.5 12.2 0.7 21.2 60.7 46.2 49.2 4.0 20.5 26.2 8.6 12.0 29.5 0.9 14.9 13.3 13.7 1.9 24.1 10.9 44.4 13.7 6.9 7.6 2.7 11.0 8.7 13.3 9.7 11.9 7.2 10.7 13.8 12.3 15.0 10.9 13.4 10.2 102.8 112.2 97.8 12.1 37.3 91.1 110.0 59.1 55.2 3.0 44.7 43.2 62.3 18.6 48.1 69.9 0.0 99.1 83.9 0.4 25.4 24.5 59.2 39.8 141.4 126.0 0.0 38.3 132.7 47.3 112.6 161.8 36.7 42.0 20.3 40.8 162.8 29.1 126.3 1.7 136.1 0.5 22.4 123.4 80.2 15.5 88.9 103.8 55.2 153.6 81.2 20.8 93.7 116.1 19.7 96.4 1.3 98.9 23.3 107.0 0.3 36.4 54.1 1.4 78.9 113.6 185.9 6.7 14.5 47.3 82.5 398.3 113.0 53.4 0.5 175.5 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 REXO2 "CGI-114, DKFZP566E144, SFN" ENSG00000076043 "RNA exonuclease 2" Q9Y3B8 11 114439435-114450279 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038450, HPA038451" Enhanced Supported "Nucleoli,Focal adhesion sites,Mitochondria" NA NA 340000 "Cluster 6: Non-specific - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "Nucleoli, Focal adhesion sites" "HPA038450: AB_10672516, HPA038451: AB_10697391" "unprognostic (3.26e-3)" "unprognostic (2.36e-2)" "prognostic favorable (6.51e-4)" "unprognostic (6.84e-3)" "unprognostic (5.80e-3)" "unprognostic (1.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.78e-1)" "unprognostic (8.18e-3)" "unprognostic (2.49e-2)" "unprognostic (2.17e-3)" "unprognostic (1.02e-1)" "unprognostic (1.73e-2)" "unprognostic (6.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.69e-2)" "prognostic unfavorable (6.70e-4)" 51.1 57.2 23.5 40.3 25.9 55.0 57.1 26.3 31.5 73.4 28.6 80.4 24.3 71.5 46.5 65.8 38.1 47.8 140.3 24.0 29.5 102.5 50.2 42.0 32.5 30.3 28.1 69.0 45.5 154.5 32.5 56.9 29.7 72.5 47.2 9.2 115.3 58.0 40.8 50.5 33.1 106.7 26.6 44.8 65.4 53.5 25.7 30.4 36.5 40.5 37.1 68.3 64.4 29.9 159.3 92.7 32.1 88.4 254.6 268.7 81.9 266.3 192.9 122.6 155.4 244.9 261.2 88.8 258.2 220.8 185.4 97.4 74.1 219.5 201.5 86.9 61.3 98.1 136.0 144.7 339.2 72.3 29.5 190.8 206.0 157.4 163.7 214.1 223.1 84.7 183.9 48.6 278.5 38.7 49.4 84.0 102.3 119.1 160.3 45.7 112.1 317.1 177.0 126.9 59.8 38.5 122.7 86.7 110.8 134.8 184.9 35.6 231.4 162.5 194.2 124.0 161.6 39.7 52.4 146.3 111.3 165.2 89.7 64.3 14.0 21.3 32.2 19.2 37.2 37.6 47.9 41.1 18.8 29.2 43.0 35.1 3.5 45.2 20.6 70.1 75.3 29.1 23.5 25.9 26.3 31.5 24.0 29.5 30.3 28.1 29.7 26.6 25.7 29.9 82.9 105.8 56.4 20.9 42.3 138.9 146.5 189.1 88.2 14.9 99.2 100.6 370.0 47.1 126.5 95.6 2.1 171.6 55.3 27.2 277.8 126.6 83.6 75.3 110.8 98.4 80.9 315.2 20.0 70.7 188.5 176.8 48.4 85.2 31.8 40.1 89.6 80.0 98.2 5.0 17.4 82.9 89.5 21.0 56.7 48.1 210.6 33.9 241.9 15.9 41.9 36.5 29.9 25.1 33.5 110.0 33.7 176.8 103.8 199.6 26.7 371.4 126.5 8.3 52.6 90.6 177.0 237.3 82.1 119.9 162.7 269.1 47.5 120.6 72.4 130.4 RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035273-93089204 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3;skeletal muscle: 199.1" "Cell type enhanced" "Detected in many" "Astrocytes: 143.3;Leydig cells: 119.0;Peritubular cells: 116.9;Prostatic glandular cells: 61.3;Skeletal myocytes: 69.3;Squamous epithelial cells: 58.3" "Cancer enriched" "Detected in many" 6 "glioma: 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 50.0;BEWO: 14.6;MOLT-4: 15.5;NTERA-2: 22.2;REH: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 2000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012343: AB_777667, HPA039880: AB_2676723, HPA044222: AB_2678861" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (8.85e-2)" "unprognostic (3.96e-3)" "unprognostic (5.73e-2)" "unprognostic (4.72e-3)" "unprognostic (2.53e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (3.59e-4)" "unprognostic (8.11e-2)" "unprognostic (2.92e-2)" "unprognostic (1.73e-1)" "unprognostic (7.98e-5)" 30.2 3.2 62.1 22.5 73.8 0.4 30.3 72.5 59.1 55.9 7.7 79.4 9.9 50.9 2.9 57.4 39.9 7.7 29.4 60.4 68.0 3.6 0.6 4.6 2.4 126.3 113.9 38.5 11.4 0.8 6.9 1.3 70.4 12.8 6.2 1.0 24.2 6.4 199.1 17.1 42.9 60.6 91.5 1.3 73.6 33.5 120.6 2.6 10.0 45.0 3.4 10.0 29.2 62.8 2.1 0.3 50.0 0.8 10.3 5.7 14.6 0.3 0.0 0.0 0.0 0.6 0.6 0.1 0.2 0.4 0.0 3.4 8.4 0.2 0.0 0.0 9.2 0.1 0.3 0.0 0.0 0.1 0.2 6.1 0.2 0.0 0.0 0.3 0.0 0.9 0.0 0.1 0.0 1.0 15.5 0.2 22.2 0.1 0.0 13.1 11.4 0.1 0.0 0.5 5.1 3.0 0.5 0.2 0.0 2.6 4.0 2.7 0.0 0.1 10.4 0.3 0.1 0.1 0.0 0.2 0.2 0.2 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 62.1 73.8 72.5 59.1 60.4 68.0 126.3 113.9 70.4 91.5 120.6 62.8 4.2 0.0 1.5 143.3 0.5 5.5 20.4 10.2 40.5 1.9 7.5 4.4 4.4 0.0 3.9 0.0 2.1 4.4 0.5 0.3 0.0 6.5 1.2 0.6 10.9 2.7 0.0 0.4 16.8 0.7 1.2 40.5 1.5 2.3 0.0 0.6 1.8 0.3 2.1 0.0 2.8 0.0 12.2 2.5 2.3 6.4 119.0 1.6 3.6 9.4 0.6 4.5 0.0 11.1 1.6 0.4 0.0 116.9 0.1 61.3 0.0 0.1 1.3 1.2 13.1 69.3 20.3 0.9 43.8 58.3 2.8 2.5 1.4 0.1 0.1 29.2 RHOB "ARH6, ARHB, MST081, RHOH6" ENSG00000143878 "Ras homolog family member B" P62745 2 20447074-20449440 "Cancer-related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Protein transport, Transport" "Developmental protein" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1272.8;Basal squamous epithelial cells: 1327.7;Hepatocytes: 1360.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 5.6;eosinophil: 18.0;intermediate monocyte: 11.4;neutrophil: 21.5;non-classical monocyte: 13.3" "Group enriched" "Detected in many" 13 "granulocytes: 21.5;monocytes: 13.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 297.9;RPTEC TERT1: 462.9;SK-BR-3: 561.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (9.66e-3)" "unprognostic (5.57e-3)" "unprognostic (8.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.85e-1)" "unprognostic (9.16e-3)" "unprognostic (5.41e-3)" "unprognostic (4.91e-2)" "unprognostic (1.04e-2)" "unprognostic (3.22e-2)" "unprognostic (3.29e-1)" "unprognostic (2.13e-2)" "prognostic favorable (4.23e-4)" "unprognostic (5.71e-2)" "unprognostic (2.56e-1)" "unprognostic (3.01e-2)" "unprognostic (2.49e-2)" 592.1 538.8 216.9 94.7 331.1 71.9 459.9 309.1 207.4 495.7 106.2 657.1 40.4 370.7 67.0 166.4 599.0 166.4 354.7 181.8 260.8 173.7 642.3 386.6 43.7 356.0 315.0 437.3 111.5 34.4 135.2 170.3 317.1 342.9 81.0 27.5 136.0 219.7 366.7 391.8 203.4 260.8 328.1 115.7 438.5 52.9 286.8 52.4 171.1 153.4 13.1 490.0 353.6 356.2 29.0 42.5 79.9 19.4 202.3 48.1 112.7 133.5 48.2 58.0 19.6 27.2 32.9 0.1 13.8 68.2 113.8 16.4 1.3 27.4 20.5 33.5 86.8 1.5 118.4 224.4 52.7 0.4 86.0 88.7 93.3 34.6 45.5 55.8 297.9 0.2 8.6 51.1 35.6 78.0 1.4 10.9 35.4 45.3 17.7 7.5 35.8 52.4 462.9 66.6 64.7 39.7 27.9 561.2 81.7 224.2 98.6 7.3 178.8 25.8 61.2 10.8 51.7 96.4 15.3 0.5 6.6 0.4 24.3 5.6 2.5 18.0 0.6 11.4 0.1 0.2 0.0 0.4 1.3 0.2 0.0 0.1 21.5 0.9 13.3 0.1 0.1 1.1 216.9 331.1 309.1 207.4 181.8 260.8 356.0 315.0 317.1 328.1 286.8 356.2 1272.8 48.1 101.9 238.3 118.7 73.9 281.4 53.0 1327.7 20.4 465.1 460.4 118.6 700.6 70.6 77.3 2.1 114.2 66.8 655.2 64.6 296.4 6.0 346.3 283.8 409.6 561.2 33.7 17.3 119.9 134.5 621.3 670.7 364.6 24.7 390.9 376.6 1360.8 190.1 33.7 18.2 496.4 73.2 418.1 136.4 20.9 270.6 473.4 96.0 43.1 31.6 344.8 5.2 32.6 91.9 200.8 318.8 197.5 191.6 212.1 203.1 289.0 89.1 19.3 927.0 542.5 800.5 6.5 22.5 701.2 90.5 270.1 62.5 244.6 340.7 85.2 RIPOR3 "C20orf175, C20orf176, dJ530I15.2, dJ530I15.3, FAM65C" ENSG00000042062 "RIPOR family member 3" Q96MK2 20 50586108-50691542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Collecting duct cells: 3.7;Endometrial stromal cells: 6.5;Fibroblasts: 3.8;monocytes: 2.0;Proximal tubular cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 16.7;HEL: 55.9;HSkMC: 33.0;K-562: 33.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA051823, HPA054759" Uncertain Approved Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051823: AB_2681626, HPA054759: AB_2682596" "unprognostic (7.23e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.38e-2)" "prognostic favorable (1.66e-5)" "unprognostic (4.96e-4)" "unprognostic (1.32e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-1)" "unprognostic (2.88e-2)" "unprognostic (1.13e-1)" "unprognostic (1.10e-3)" "unprognostic (1.98e-1)" "unprognostic (9.21e-3)" "unprognostic (1.67e-2)" "unprognostic (4.58e-2)" 19.4 13.3 2.7 3.4 3.0 22.4 11.7 2.7 3.5 38.5 5.1 8.5 2.5 18.2 1.0 5.3 27.7 3.2 16.6 2.7 2.6 28.9 14.1 5.3 4.7 3.0 2.9 8.3 3.0 0.8 9.1 1.9 2.9 6.0 1.5 0.1 6.9 0.6 7.8 5.5 11.3 4.4 2.6 7.5 5.8 6.1 2.8 4.7 7.5 3.8 1.3 8.2 16.6 2.6 0.0 0.0 0.9 0.0 36.0 16.7 0.1 0.0 11.6 0.0 0.2 0.3 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 55.9 0.0 0.2 4.3 0.0 0.0 33.0 0.0 1.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.9 0.0 3.2 0.0 0.0 5.3 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 2.7 3.0 2.7 3.5 2.7 2.6 3.0 2.9 2.9 2.6 2.8 2.6 1.1 3.2 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.6 3.7 0.0 0.6 0.4 0.0 0.0 0.5 0.0 0.8 6.5 0.2 0.0 0.0 0.0 0.4 0.4 3.8 0.0 1.6 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.9 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.0 RND3 "ARHE, Rho8, RhoE" ENSG00000115963 "Rho family GTPase 3" P61587 2 150468195-150539011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 155.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1633.3;Endometrial stromal cells: 521.7;Suprabasal keratinocytes: 924.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 680.9;BJ hTERT+: 1331.5;hTERT-HME1: 650.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060504 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA060504: AB_2684295" "unprognostic (8.03e-2)" "unprognostic (3.04e-2)" "unprognostic (2.36e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-2)" "unprognostic (4.69e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-3)" "unprognostic (4.23e-2)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (1.47e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (2.03e-2)" 58.0 50.0 12.1 27.8 8.6 1.2 99.2 8.6 9.2 47.8 8.1 27.2 16.8 45.2 7.3 155.4 14.0 59.9 23.6 8.8 10.2 14.6 131.9 23.2 11.4 8.5 8.4 8.4 16.2 1.9 7.8 46.4 18.4 46.0 27.1 5.2 28.9 37.7 14.4 50.5 19.9 62.3 7.1 39.5 20.2 4.7 14.2 8.2 7.4 14.0 24.5 108.8 44.1 7.0 46.5 27.5 49.2 93.8 137.1 65.7 0.4 680.9 1331.5 335.0 189.1 34.8 31.4 0.0 42.5 277.8 173.1 108.2 1.9 43.9 268.5 0.0 20.4 0.0 35.1 1.1 391.2 0.1 0.5 46.2 78.6 344.9 650.7 62.9 65.4 0.4 0.0 158.2 145.0 27.5 0.3 0.3 15.4 47.5 42.3 0.1 37.7 21.5 74.5 80.7 15.0 46.4 71.5 29.3 37.2 35.9 33.3 1.1 67.4 296.3 55.3 137.8 73.8 35.7 0.4 0.4 234.2 0.1 209.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 8.6 8.6 9.2 8.8 10.2 8.5 8.4 18.4 7.1 14.2 7.0 81.3 38.5 5.8 2.0 0.4 1633.3 231.2 304.7 368.2 40.5 131.9 218.1 95.6 45.8 192.5 9.2 14.6 71.7 1.8 359.8 3.9 63.4 1.9 389.9 521.7 46.3 32.8 5.3 0.6 14.6 12.8 353.4 56.6 400.3 4.5 0.6 26.4 129.3 12.2 1.7 35.3 130.5 97.6 76.8 83.0 2.2 10.5 12.0 136.9 15.0 0.0 9.6 0.0 0.5 0.5 107.4 249.5 10.5 4.6 102.4 174.8 3.9 157.0 2.7 19.7 182.0 166.8 0.9 3.4 458.0 924.7 91.1 10.9 36.8 117.5 262.9 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266682-127288567 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favorable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favorable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 52.9 37.0 49.5 32.4 56.0 10.6 42.7 79.4 61.2 48.1 36.2 40.5 21.9 57.4 60.8 25.3 42.4 38.6 46.9 50.7 51.6 37.1 31.8 38.7 35.1 53.2 52.1 49.5 23.3 40.0 33.3 51.8 56.8 31.7 30.9 48.1 31.2 34.5 114.9 29.5 31.1 45.9 55.2 47.1 29.9 31.3 52.5 24.3 47.1 91.5 33.3 36.9 34.3 61.5 13.2 16.2 60.3 53.6 54.7 54.3 22.2 43.5 69.0 22.8 32.4 21.3 19.3 23.6 30.3 35.7 36.2 16.4 18.1 20.4 32.9 27.6 16.0 30.3 21.8 30.0 54.0 18.0 20.6 47.6 42.1 26.1 51.1 52.5 40.6 23.2 33.0 22.5 50.7 25.2 17.9 32.0 22.1 8.1 17.1 22.6 15.7 12.1 32.4 14.3 36.0 36.6 17.1 23.6 27.7 35.5 16.1 60.8 48.3 39.7 13.1 41.8 31.7 32.3 22.0 15.6 30.5 31.0 38.5 27.5 30.0 26.6 14.3 32.4 14.7 17.4 12.2 16.3 22.8 17.9 11.0 15.5 37.0 19.8 40.1 11.7 15.0 16.1 49.5 56.0 79.4 61.2 50.7 51.6 53.2 52.1 56.8 55.2 52.5 61.5 24.6 35.3 29.3 35.6 23.7 17.7 14.3 15.1 18.8 34.7 16.9 14.7 38.9 31.5 16.7 9.2 4.2 29.0 14.7 13.5 41.1 28.0 52.5 15.7 29.5 30.5 20.4 12.8 53.5 15.8 27.2 50.6 7.1 11.5 22.2 28.1 31.4 30.5 26.3 30.3 54.5 12.1 38.7 68.4 24.6 45.4 69.6 29.9 46.2 42.2 31.1 41.1 28.8 56.3 76.5 18.0 17.0 66.5 9.3 26.3 15.7 51.7 23.9 20.9 32.9 36.2 31.9 41.7 24.9 15.0 20.0 38.4 20.8 36.0 10.9 25.9 RNF222 ENSG00000189051 "Ring finger protein 222" A6NCQ9 17 8390704-8397826 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 16.9;skin 1: 6.9;vagina: 5.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.3;NK-cells: 2.1;Rod photoreceptor cells: 1.0;Suprabasal keratinocytes: 1.4;Syncytiotrophoblasts: 1.2;Urothelial cells: 1.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048916 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA048916: AB_2680555" "unprognostic (2.49e-1)" "unprognostic (4.19e-2)" "unprognostic (2.32e-2)" "unprognostic (8.19e-4)" "unprognostic (2.81e-1)" "unprognostic (5.30e-2)" "unprognostic (2.02e-1)" "unprognostic (3.93e-2)" "unprognostic (9.55e-2)" "unprognostic (7.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-3)" "unprognostic (5.82e-2)" "unprognostic (6.70e-2)" "unprognostic (5.98e-3)" "unprognostic (3.97e-2)" 0.0 0.0 0.2 0.1 0.1 1.2 0.3 0.6 0.2 3.3 0.2 0.0 0.0 0.0 0.1 16.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 1.9 0.0 0.1 6.9 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.2 0.0 5.9 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.8 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.2 0.2 0.0 0.3 0.1 0.2 0.1 0.2 0.4 0.2 0.0 1.3 0.0 0.0 0.1 0.6 0.0 0.0 0.2 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.0 0.0 0.7 0.0 0.1 0.0 1.0 0.0 0.4 0.2 0.2 0.1 0.0 1.4 1.2 0.7 0.1 0.0 1.7 ROBO3 "FLJ21044, HGPPS, HGPS, RBIG1" ENSG00000154134 "Roundabout guidance receptor 3" Q96MS0 11 124865432-124881471 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 6.4" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Muller glia cells: 45.3" "Cancer enhanced" "Detected in many" "glioma: 5.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "AF22: 18.4" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Low region specificity" "Detected in many" HPA071053 Approved "Vesicles,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA071053: " "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "unprognostic (4.95e-3)" "unprognostic (3.42e-2)" "unprognostic (3.84e-2)" "unprognostic (6.25e-2)" "unprognostic (6.95e-3)" "unprognostic (9.65e-2)" "unprognostic (1.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (7.15e-2)" "unprognostic (3.75e-8)" "unprognostic (7.27e-3)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (4.91e-3)" 2.8 1.8 0.5 0.0 0.3 0.2 1.9 0.0 3.2 0.7 0.0 1.3 0.3 0.8 0.0 0.7 2.0 0.0 1.8 0.7 0.2 1.6 0.4 1.1 0.1 0.9 0.9 6.4 0.7 0.0 0.8 0.2 0.2 1.4 0.0 0.2 1.2 0.0 0.5 0.7 0.9 0.8 0.2 1.6 0.6 1.2 1.7 0.0 1.4 0.0 0.0 0.7 1.2 0.9 0.0 0.0 18.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.6 0.9 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.0 3.2 0.7 0.2 0.9 0.9 0.2 0.2 1.7 0.9 13.2 0.0 7.3 32.3 0.4 2.9 14.5 16.2 4.0 1.9 5.9 10.9 2.7 1.5 5.9 12.9 0.0 0.2 8.5 2.1 0.0 9.3 0.4 0.4 0.5 11.4 3.5 2.1 6.9 0.8 0.2 19.0 0.5 0.7 8.9 19.0 7.5 0.3 1.6 0.0 2.3 2.4 10.2 1.6 20.1 0.6 13.4 8.0 3.6 11.2 1.6 45.3 8.2 4.5 9.2 1.2 2.5 8.2 0.7 8.2 1.0 0.8 0.6 2.1 0.0 14.3 4.4 10.1 10.8 2.3 1.0 0.1 3.6 3.5 2.7 6.5 RTL3 "FLJ38865, Mar3, Mart3, SIRH9, ZCCHC5, ZHC5" ENSG00000179300 "Retrotransposon Gag like 3" Q8N8U3 X 78656068-78659328 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 1.8;GAMG: 1.4;HBF TERT88: 2.4;hTEC/SVTERT24-B: 1.7;RH-30: 2.1;U-251 MG: 1.6" "Region enriched" "Detected in single" 9 "hippocampal formation: 2.8" "HPA051991, HPA053174, HPA075136" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA051991: AB_2681683, HPA053174: AB_2682069, HPA075136: AB_2686737" "unprognostic (3.43e-1)" "unprognostic (1.06e-1)" "unprognostic (1.29e-1)" "unprognostic (6.74e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.69e-2)" "unprognostic (2.85e-1)" "unprognostic (4.00e-6)" "unprognostic (1.53e-2)" "unprognostic (3.64e-1)" "unprognostic (2.49e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 1.0 1.1 0.0 0.0 0.0 0.0 1.8 1.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.6 0.0 1.6 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RXRG NR2B3 ENSG00000143171 "Retinoid X receptor gamma" P48443 1 165400922-165445355 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;pituitary gland: 29.9;retina: 24.3;skeletal muscle: 49.7" "Group enriched" "Detected in some" 4 "Astrocytes: 13.4;Cone photoreceptor cells: 25.0;Melanocytes: 28.4;Muller glia cells: 16.8;Sertoli cells: 13.1;Skeletal myocytes: 35.9" "Group enriched" "Detected in many" 13 "melanoma: 25.7;thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 39.4" "Region enriched" "Detected in many" 5 "basal ganglia: 100.2" "Low region specificity" "Detected in many" "CAB002615, HPA012933" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB002615: , HPA012933: AB_2732406" "unprognostic (2.29e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.66e-1)" "unprognostic (4.29e-2)" "unprognostic (6.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.13e-2)" "unprognostic (6.86e-2)" "unprognostic (2.95e-2)" "unprognostic (5.41e-3)" "unprognostic (2.52e-2)" "unprognostic (6.12e-3)" "unprognostic (1.18e-1)" "prognostic favorable (9.40e-5)" "unprognostic (5.03e-2)" 2.4 3.2 14.6 0.4 16.6 0.0 1.0 11.7 17.4 3.0 11.7 4.1 0.7 1.1 0.7 1.0 2.8 0.6 5.3 12.4 21.5 0.2 0.3 2.8 0.3 25.6 14.8 1.0 2.1 0.1 29.9 0.7 22.2 1.1 2.0 24.3 1.2 1.4 49.7 2.3 1.6 1.2 13.6 0.4 1.4 1.0 32.1 0.1 0.7 7.6 0.0 1.6 2.1 15.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 39.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 16.6 11.7 17.4 12.4 21.5 25.6 14.8 22.2 13.6 32.1 15.6 0.9 0.0 0.0 13.4 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 2.8 5.0 0.0 28.4 0.0 0.0 16.8 0.0 1.0 1.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.5 13.1 35.9 3.4 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 SAV1 "salvador, WW45, WWP4" ENSG00000151748 "Salvador family WW domain containing protein 1" Q9H4B6 14 50632058-50668306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001808 Approved Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA001808: AB_2666441" "prognostic favorable (2.92e-5)" "unprognostic (5.17e-2)" "unprognostic (1.24e-1)" "unprognostic (1.52e-2)" "unprognostic (4.38e-1)" "unprognostic (1.42e-1)" "unprognostic (1.44e-3)" "unprognostic (3.00e-2)" "unprognostic (1.82e-1)" "unprognostic (1.37e-1)" "unprognostic (1.41e-3)" "unprognostic (5.20e-2)" "prognostic favorable (3.83e-6)" "unprognostic (2.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.28e-2)" "unprognostic (1.90e-3)" 32.2 16.4 14.0 12.8 16.7 7.3 35.3 15.1 16.9 24.5 22.0 17.0 15.3 23.3 18.8 15.8 21.2 26.2 24.2 12.8 15.0 22.9 17.6 20.2 15.7 16.5 15.1 37.7 34.4 27.0 8.5 17.0 16.1 27.6 12.6 17.6 45.5 19.2 23.1 17.8 13.2 17.7 14.7 18.6 18.9 30.6 16.6 10.3 34.2 27.1 14.7 16.7 18.7 19.6 96.3 10.7 17.8 12.4 43.5 39.8 22.4 26.6 87.3 34.1 43.4 16.0 47.8 14.9 63.9 26.4 17.8 42.8 25.7 28.9 62.9 45.6 20.8 16.4 16.4 11.4 21.3 17.9 14.0 24.9 36.5 15.3 33.8 25.8 24.5 15.9 27.5 7.2 42.5 17.9 15.1 11.0 33.1 21.6 17.3 17.2 49.5 6.1 21.5 13.6 22.2 16.8 47.1 27.7 41.3 28.9 20.3 18.0 17.7 16.2 55.5 22.4 16.4 11.3 15.4 9.0 11.1 7.2 22.1 0.6 0.3 0.0 0.9 0.3 0.9 3.3 0.7 0.5 0.3 3.4 0.5 0.7 0.5 0.5 0.4 1.2 1.0 0.4 14.0 16.7 15.1 16.9 12.8 15.0 16.5 15.1 16.1 14.7 16.6 19.6 76.4 35.3 44.0 9.4 35.8 65.9 37.2 19.1 24.5 19.6 76.4 60.6 39.1 15.7 35.1 18.4 25.0 19.9 14.7 11.2 17.6 40.5 92.5 39.6 47.3 76.9 5.4 27.0 10.4 47.6 23.0 59.3 11.7 58.1 2.5 46.4 59.3 14.5 10.5 5.0 10.0 10.1 10.2 13.5 61.5 26.1 66.8 34.1 30.2 12.2 11.6 26.9 2.1 12.5 27.0 66.5 14.6 42.5 7.4 81.4 12.1 16.3 33.3 26.4 6.6 41.8 45.1 41.4 38.8 14.6 59.5 23.1 9.4 17.7 9.6 34.1 SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 90.0" "Group enriched" "Detected in some" 4 "Fibroblasts: 174.0;Leydig cells: 135.8;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 211 "dendritic cells: 21.1" "Cell line enriched" "Detected in some" 20 "ASC diff: 229.1" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" HPA024661 Approved NA NA 1400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA024661: AB_1853902" "unprognostic (2.76e-2)" "unprognostic (7.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.53e-2)" "unprognostic (2.34e-2)" "unprognostic (4.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.13e-2)" "unprognostic (2.40e-1)" "unprognostic (4.21e-2)" "unprognostic (1.10e-1)" "unprognostic (7.09e-6)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" 60.5 4.0 0.4 7.2 0.8 0.0 34.6 0.8 1.8 16.6 4.9 38.5 8.7 2.9 8.2 21.1 23.7 22.5 90.0 0.6 0.4 1.0 4.1 20.2 2.4 0.3 0.2 11.2 2.4 0.2 5.4 12.5 0.2 8.4 33.7 0.3 29.0 3.3 15.1 31.1 26.3 6.5 0.5 3.3 27.3 11.6 0.2 3.2 21.1 34.5 2.1 77.1 36.8 0.3 0.0 7.9 0.0 0.0 229.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 11.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.1 0.4 0.8 0.8 1.8 0.6 0.4 0.3 0.2 0.2 0.5 0.2 0.3 7.1 0.0 0.0 0.0 0.1 6.5 0.1 0.0 0.6 0.0 0.5 0.6 4.6 0.0 0.0 0.0 0.0 0.1 6.7 0.2 0.0 0.0 1.5 0.7 27.9 2.4 0.0 0.0 0.3 0.0 0.4 174.0 4.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 2.9 0.0 0.0 0.0 17.0 4.6 135.8 1.3 7.2 5.6 0.0 1.9 0.0 0.0 0.2 0.0 0.0 11.3 0.8 0.1 0.0 0.0 0.0 0.1 0.0 7.4 3.6 0.7 1.1 0.9 6.0 0.1 1.1 44.5 0.3 0.1 SCN7A "NaG, Nav2.1, Nav2.2, SCN6A" ENSG00000136546 "Sodium voltage-gated channel alpha subunit 7" Q01118 2 166403573-166611482 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 45.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 102.0;Leydig cells: 100.9;Peritubular cells: 159.9;Sertoli cells: 151.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "HDLM-2: 7.9;HMC-1: 4.5;Karpas-707: 5.8;SK-BR-3: 15.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.6" HPA072715 Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA072715: " "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (9.72e-2)" "unprognostic (7.43e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (5.21e-2)" "unprognostic (6.84e-3)" "unprognostic (6.88e-2)" "unprognostic (1.27e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-2)" "unprognostic (1.47e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-4)" 4.6 8.6 3.4 3.4 3.0 0.3 10.2 0.1 1.8 7.8 0.0 35.8 3.4 9.0 6.3 10.1 10.9 3.8 20.6 1.1 7.1 1.8 1.2 27.6 0.5 4.0 7.1 45.4 4.9 0.7 1.0 12.3 5.4 11.0 8.5 10.6 6.1 10.1 7.2 2.4 6.8 7.6 2.9 3.2 7.8 5.6 9.8 3.2 1.2 15.0 0.4 4.7 7.1 1.2 0.1 0.1 0.7 0.9 0.2 0.0 0.8 0.7 0.0 1.3 0.0 0.6 0.2 0.4 0.1 0.0 0.3 0.3 0.1 0.1 0.0 7.9 0.5 0.2 1.5 0.6 0.0 0.2 4.5 0.0 0.0 0.4 0.1 0.4 0.0 0.4 1.2 5.8 0.0 1.0 0.8 0.5 1.1 0.3 0.3 0.0 0.5 0.0 0.1 0.8 0.2 0.4 0.3 15.4 0.0 0.3 0.4 0.1 0.4 0.2 1.0 0.7 0.4 1.0 0.3 1.1 0.2 0.2 0.4 1.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.8 3.4 3.0 0.1 1.8 1.1 7.1 4.0 7.1 5.4 2.9 9.8 1.2 1.4 0.0 1.1 1.0 0.0 0.3 0.2 0.0 5.7 21.5 0.2 0.3 16.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 2.4 0.0 0.3 4.1 0.0 0.0 7.7 0.0 0.0 102.0 0.0 0.0 15.9 0.1 9.3 0.0 0.2 0.0 20.9 0.0 0.0 0.0 1.2 4.1 100.9 1.8 5.4 14.0 0.0 4.9 0.0 14.1 0.3 0.1 0.0 159.9 1.2 0.5 0.0 0.5 0.0 1.8 151.2 16.7 26.1 0.5 1.2 1.7 1.1 0.0 0.2 0.3 0.0 0.3 SCX "bHLHa41, bHLHa48, SCXA, SCXB" ENSG00000260428 "Scleraxis bHLH transcription factor" Q7RTU7 8 144266453-144268481 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 38.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.2;Horizontal cells: 16.8" "Group enriched" "Detected in all" 6 "endometrial cancer: 12.8;ovarian cancer: 34.4;thyroid cancer: 37.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.8;HaCaT: 5.3" "Region enhanced" "Detected in many" "cerebellum: 10.7" "Low region specificity" "Detected in some" HPA043183 Uncertain NA NA "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA043183: AB_2678357" "unprognostic (5.32e-2)" "unprognostic (1.06e-2)" "unprognostic (7.37e-3)" "unprognostic (1.87e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (2.03e-2)" "unprognostic (2.27e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-2)" "unprognostic (6.86e-2)" "unprognostic (2.10e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (7.89e-3)" 1.4 3.4 3.0 0.9 2.3 0.6 1.4 7.8 7.0 7.8 2.9 8.3 0.9 2.9 0.5 3.4 3.8 0.1 11.0 2.7 2.9 8.4 2.1 3.5 0.4 6.2 1.9 2.5 3.8 0.8 19.6 0.2 5.4 4.5 0.2 0.1 2.7 0.1 13.8 3.2 5.0 0.2 0.9 4.6 5.9 5.2 2.3 0.7 38.1 1.2 0.1 2.6 3.2 1.8 2.0 0.4 0.1 0.5 0.0 0.0 4.8 0.1 0.0 0.1 0.0 0.1 1.4 1.3 1.4 0.2 0.2 5.3 0.0 0.0 0.0 0.9 0.8 0.3 1.9 0.2 0.2 0.1 2.2 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.2 0.6 0.1 3.0 0.5 1.1 1.1 0.4 2.3 1.6 0.2 0.8 0.1 2.0 0.2 0.9 0.5 1.8 2.2 0.1 2.3 0.9 0.3 0.4 3.5 1.6 0.3 1.8 0.6 0.3 0.8 1.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.3 7.8 7.0 2.7 2.9 6.2 1.9 5.4 0.9 2.3 1.8 3.4 0.0 2.7 8.5 2.5 0.0 1.2 0.0 0.6 14.2 6.7 8.3 6.2 1.5 1.3 3.7 0.0 1.5 7.5 2.2 1.9 0.6 0.2 5.7 1.4 1.2 2.4 0.0 5.9 1.4 0.6 1.2 8.2 7.1 0.0 3.2 0.4 0.4 0.4 16.8 8.5 2.3 0.0 0.6 0.0 0.9 0.3 0.9 0.0 1.0 0.0 8.2 1.0 2.5 0.3 1.5 2.1 0.7 0.7 2.7 1.5 0.2 0.0 1.5 0.0 4.2 6.4 2.5 9.0 0.6 0.0 1.1 3.1 0.3 1.8 1.0 SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 460.8;thyroid gland: 424.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.7;Hepatocytes: 235.5;Smooth muscle cells: 183.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.6" "Cell line enhanced" "Detected in many" "AF22: 643.1;EFO-21: 297.8;fHDF/TERT166: 288.4;RPTEC TERT1: 341.3;U-138 MG: 305.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA044416" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB025123: , HPA044416: AB_2678934" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" 109.5 36.3 35.2 35.9 41.0 10.2 66.6 37.6 49.9 157.0 26.4 77.9 21.8 76.0 15.2 50.1 84.6 44.5 68.9 32.1 51.8 88.9 460.8 56.8 18.9 41.1 46.6 170.5 61.2 30.2 61.5 124.4 37.5 63.4 40.1 29.7 25.0 104.4 19.9 25.3 39.8 90.9 38.5 25.8 41.9 25.5 49.6 5.3 424.5 58.5 8.0 84.0 58.1 33.7 0.5 0.3 643.1 0.3 230.2 214.1 0.6 94.8 113.4 54.3 60.5 19.8 0.2 0.2 297.8 288.4 8.0 0.5 114.3 1.8 47.1 0.3 44.4 0.6 56.7 250.2 7.4 1.9 2.9 83.1 2.8 123.5 3.1 210.2 1.9 0.1 64.3 0.3 23.1 6.0 0.3 16.9 68.1 0.0 0.7 0.7 101.5 2.4 341.3 57.2 19.1 49.5 0.2 0.3 4.9 217.8 27.6 73.0 51.3 305.1 91.5 1.5 53.2 6.0 0.3 1.1 96.9 0.4 97.5 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 13.6 0.0 0.1 0.0 0.0 0.6 35.2 41.0 37.6 49.9 32.1 51.8 41.1 46.6 37.5 38.5 49.6 33.7 11.9 57.7 38.1 93.7 1.7 53.8 78.9 29.6 15.9 36.6 41.4 30.2 32.7 37.1 5.1 57.0 12.5 1.9 0.5 0.1 29.4 14.4 31.6 29.3 65.1 10.7 3.5 10.7 4.6 15.3 2.5 229.7 9.7 76.4 1.3 44.3 17.5 235.5 109.8 5.0 22.0 1.5 138.4 20.5 154.7 18.6 52.5 62.9 62.2 21.5 68.2 17.4 0.0 7.1 1.7 8.9 1.2 104.9 2.5 41.7 0.8 56.4 4.0 12.5 32.9 100.0 183.1 5.5 57.6 1.3 39.2 3.8 4.2 33.3 5.7 17.6 SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 92.2;Breast myoepithelial cells: 93.5;Fibroblasts: 109.6;Ionocytes: 91.6;Oligodendrocytes: 223.7;Respiratory ciliated cells: 103.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.6" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.6" "Cell line enhanced" "Detected in many" "GAMG: 252.7;RT4: 238.3;T-47d: 267.0;U-2197: 349.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 13000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: AB_10797389" "unprognostic (1.93e-2)" "unprognostic (2.54e-3)" "unprognostic (4.94e-1)" "unprognostic (9.86e-2)" "unprognostic (6.74e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (9.28e-3)" "unprognostic (1.91e-3)" "unprognostic (1.39e-2)" "unprognostic (9.01e-2)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.07e-2)" "unprognostic (1.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-2)" 53.8 9.5 4.9 12.7 8.1 0.8 57.3 9.1 5.5 53.0 2.6 38.4 10.6 42.7 23.1 20.5 15.4 30.0 22.1 11.0 12.7 10.0 1.3 18.4 1.0 15.0 8.0 48.5 2.6 0.8 3.7 6.0 17.5 66.6 31.3 1.0 27.3 42.3 19.3 17.9 14.1 44.4 10.0 22.2 20.6 12.9 8.4 1.4 1.8 34.3 1.1 69.8 14.4 12.8 6.6 77.0 156.4 0.6 35.2 82.5 0.3 51.8 59.7 25.9 32.5 12.4 144.7 0.0 2.1 17.7 252.7 31.2 0.7 47.0 42.4 0.1 15.8 9.9 63.6 0.7 41.3 0.7 0.2 36.1 32.3 63.6 62.0 220.2 0.5 0.0 0.5 0.1 46.4 113.7 0.2 0.3 1.4 22.2 12.2 0.1 75.5 1.2 142.9 238.3 0.8 82.4 145.7 38.9 9.5 66.3 267.0 0.2 125.2 140.1 64.2 349.2 93.9 1.2 0.0 0.1 52.8 0.0 142.3 49.6 5.7 0.9 0.0 2.4 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 2.6 0.0 1.9 3.3 0.0 1.7 4.9 8.1 9.1 5.5 11.0 12.7 15.0 8.0 17.5 10.0 8.4 12.8 7.4 9.6 8.9 3.3 0.3 26.4 41.8 92.2 10.8 0.3 15.8 93.5 38.2 1.5 39.8 7.3 6.2 0.5 1.7 56.1 1.9 3.8 0.5 20.3 11.9 7.7 6.0 4.6 41.7 6.6 1.3 109.6 17.9 34.4 5.1 13.2 1.1 0.0 8.8 0.0 16.7 15.7 91.6 3.1 14.9 2.3 7.8 9.0 55.2 20.6 8.3 1.5 1.0 3.0 223.7 68.2 12.4 52.3 0.0 53.7 12.5 0.4 103.0 0.6 0.0 38.8 17.3 0.7 2.7 3.0 18.9 0.3 1.5 9.9 30.4 70.0 SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 9176.5;pancreas: 4910.2" "Cell type enhanced" "Detected in some" "Ductal cells: 20.9;Exocrine glandular cells: 33.0;Fibroblasts: 68.6;Late spermatids: 12.2;Pancreatic endocrine cells: 18.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "Hep G2: 449.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" NA NA 697000000000 94000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" 91.8 58.0 100.4 43.4 116.5 2.1 371.0 117.7 293.8 368.8 110.3 79.5 11.7 44.9 11.5 42.5 116.6 146.0 311.7 103.6 320.0 215.5 9176.5 169.9 5.0 196.3 183.1 181.5 4910.2 1.0 271.2 14.6 138.3 580.5 13.3 131.5 1505.8 54.9 177.8 55.7 91.6 83.1 141.4 31.7 290.5 66.9 176.3 2.6 72.6 38.9 6.4 207.4 70.4 173.0 0.2 0.5 0.0 0.3 0.2 0.8 0.3 0.1 0.1 0.0 0.0 1.2 4.9 0.6 4.5 0.0 3.3 0.9 0.0 4.4 0.0 2.7 0.0 1.0 0.2 449.9 56.9 1.9 0.7 52.0 63.9 0.0 2.5 5.4 0.0 0.0 0.3 0.2 0.0 17.1 0.5 0.5 0.8 1.6 0.0 0.6 2.2 0.2 3.8 0.2 0.1 0.0 1.8 2.5 65.6 0.4 2.4 0.0 0.6 0.0 8.5 0.1 19.4 1.1 2.0 2.1 0.4 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 116.5 117.7 293.8 103.6 320.0 196.3 183.1 138.3 141.4 176.3 173.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.5 1.8 0.0 5.6 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 20.9 3.7 0.2 0.1 0.3 0.0 0.0 0.0 33.0 0.0 68.6 9.7 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.3 0.0 0.0 1.0 0.2 0.0 0.0 0.0 18.7 0.0 0.4 0.3 0.5 0.0 0.1 1.5 0.0 0.0 1.7 0.8 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1875.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 697.8;Cytotrophoblasts: 795.6;Fibroblasts: 951.9;Hepatocytes: 765.0;Leydig cells: 1818.0;Peritubular cells: 1045.7" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enhanced" "Detected in many" "hippocampal formation: 85.4" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1454.4" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1454.4" "Group enriched" "Detected in many" 4 "ASC diff: 1232.0;ASC TERT1: 956.3;Hep G2: 606.0;HHSteC: 410.6;HSkMC: 1313.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" NA NA 9290000000 44000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" 535.5 57.5 5.7 124.2 9.6 11.9 490.2 17.9 28.0 558.7 1875.2 131.3 41.9 358.2 90.2 109.3 557.4 559.7 376.5 85.4 1.1 35.1 974.8 158.9 133.5 0.1 5.1 408.3 207.6 11.2 62.4 311.6 1.3 202.8 52.0 61.4 124.6 105.8 434.8 162.9 131.7 221.7 2.8 133.2 124.7 277.7 25.4 106.2 193.1 465.5 117.7 323.4 273.5 7.0 0.5 3.7 2.8 2.0 1232.0 956.3 20.4 56.8 49.8 0.6 0.0 9.7 0.5 2.3 1.9 71.8 0.3 3.2 86.0 4.4 0.0 0.6 46.0 1.0 1.2 606.0 410.6 1.1 1.1 1313.4 6.9 0.9 1.1 11.4 0.6 4.2 117.5 0.4 63.2 0.2 7.0 7.2 30.7 0.3 1.0 2.9 219.9 1.6 0.1 6.0 1.9 42.2 0.7 0.7 57.0 3.4 6.7 184.2 2.0 0.5 17.6 14.1 1.2 0.7 2.4 28.1 1.7 0.6 0.8 0.1 12.0 1.1 0.6 4.4 0.4 9.0 0.7 0.9 79.8 5.2 2.0 5.5 1.7 1.3 0.2 1454.4 0.8 14.2 5.7 9.6 17.9 28.0 85.4 1.1 0.1 5.1 1.3 2.8 25.4 7.0 59.0 3.2 10.4 0.3 10.8 95.0 238.0 697.8 27.9 59.3 6.7 71.2 12.1 11.5 167.7 1.8 223.1 795.6 226.1 0.0 0.0 0.3 11.2 12.5 372.4 26.2 0.0 19.2 5.3 24.5 98.7 951.9 11.2 6.7 22.9 1.7 28.2 765.0 151.6 3.3 2.6 0.0 366.2 60.4 262.6 53.0 1818.0 79.0 108.5 9.4 79.0 11.6 1.0 0.5 2.0 6.8 0.1 1045.7 7.0 155.5 0.2 27.3 105.5 39.1 19.7 193.3 202.8 12.7 8.7 4.5 78.6 534.8 14.3 10.2 0.3 47.7 SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing 7, histone lysine methyltransferase" Q8WTS6 4 139495941-139606699 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA058111: AB_2683607" "prognostic unfavorable (8.28e-4)" "unprognostic (7.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.71e-2)" "unprognostic (9.10e-2)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.16e-3)" "unprognostic (1.17e-1)" "unprognostic (6.92e-2)" "unprognostic (6.56e-3)" 44.7 18.5 17.8 15.1 17.7 9.7 27.3 19.3 17.3 40.5 21.2 23.5 7.3 33.0 12.6 28.1 18.8 26.7 41.0 16.6 19.4 10.1 50.1 19.2 11.7 25.0 20.3 19.6 21.9 34.7 8.8 19.1 24.7 35.1 15.3 11.5 16.2 20.6 106.6 22.7 12.1 34.8 24.6 17.0 20.1 14.4 24.5 10.1 14.1 73.7 15.9 23.4 18.2 29.2 28.4 37.2 13.0 7.8 77.1 65.9 29.6 65.7 67.3 32.4 27.1 22.7 37.2 68.0 25.5 110.5 22.4 13.9 44.3 51.3 52.4 32.8 33.0 8.9 45.5 0.8 38.4 31.9 12.9 57.7 58.6 52.1 54.6 41.2 41.7 27.8 5.5 96.1 42.3 46.8 21.0 4.6 6.4 40.8 23.9 19.7 48.4 37.3 31.5 25.3 55.3 18.5 44.7 63.5 15.3 12.6 25.3 28.0 68.8 57.1 40.7 68.6 55.2 89.6 86.8 42.2 65.9 31.1 28.0 0.5 3.9 0.2 0.3 2.0 2.7 1.0 1.1 1.1 4.4 1.2 0.4 0.2 0.9 0.2 3.2 2.1 3.7 1.2 17.8 17.7 19.3 17.3 16.6 19.4 25.0 20.3 24.7 24.6 24.5 29.2 28.7 6.4 18.8 17.3 8.9 17.2 14.5 14.1 12.5 5.4 24.0 14.7 43.1 20.0 15.0 9.2 12.5 26.2 4.2 4.1 0.0 22.7 1.3 3.5 35.9 29.4 1.2 3.6 21.1 21.2 16.7 39.8 16.8 7.5 2.5 2.9 37.1 70.6 20.4 8.4 42.4 13.6 18.3 31.0 20.9 4.3 23.0 19.5 10.6 19.7 19.0 15.0 0.0 36.2 29.2 22.4 4.1 28.2 13.2 38.4 1.3 4.5 14.0 12.9 19.7 35.2 23.3 3.7 2.7 17.9 22.0 46.1 9.8 9.5 11.7 20.4 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SGCB "A3b, LGMD2E, SGC" ENSG00000163069 "Sarcoglycan beta" Q16585 4 52020706-52038299 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 105.7" "Cell type enhanced" "Detected in many" "Late spermatids: 203.7" "Cancer enhanced" "Detected in all" "glioma: 56.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 104.7" "Low region specificity" "Detected in all" "HPA011422, HPA058656" Enhanced Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA011422: AB_1856795, HPA058656: AB_2683790" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (1.03e-1)" "unprognostic (1.60e-3)" "unprognostic (9.80e-2)" "unprognostic (3.42e-2)" "unprognostic (3.57e-3)" "unprognostic (1.86e-2)" "unprognostic (2.84e-2)" "unprognostic (6.04e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.53e-6)" "unprognostic (3.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (7.61e-4)" 32.7 21.6 27.1 9.5 30.3 0.5 14.7 28.0 32.2 23.4 21.4 32.9 13.1 28.1 11.1 21.9 20.5 19.5 57.2 25.3 27.7 35.0 10.8 15.2 6.1 29.7 28.4 20.1 6.5 47.0 13.9 24.2 30.3 25.0 16.2 16.6 13.5 27.2 105.7 7.2 14.9 37.3 29.0 11.1 14.0 16.0 28.3 5.6 9.2 81.3 4.5 20.4 15.7 33.4 11.4 13.7 27.8 10.6 104.7 78.5 10.1 62.8 79.9 34.5 36.2 3.7 14.9 3.0 11.8 82.9 53.5 5.5 20.9 23.1 36.7 18.8 7.8 0.2 11.8 6.8 42.8 6.8 3.6 86.8 15.9 29.9 17.3 89.8 46.1 10.7 0.1 0.1 74.5 4.4 15.1 0.1 10.0 4.6 20.4 0.0 14.8 0.2 29.2 3.8 16.2 28.4 39.9 1.9 14.1 31.0 5.2 4.1 47.0 50.8 17.0 24.1 56.6 14.9 20.4 5.5 37.5 2.4 59.7 0.3 1.0 0.0 2.1 0.5 2.1 2.6 2.5 2.3 0.5 2.3 1.7 2.2 0.5 0.3 0.4 1.0 4.2 1.0 27.1 30.3 28.0 32.2 25.3 27.7 29.7 28.4 30.3 29.0 28.3 33.4 38.9 32.1 13.1 15.3 6.6 13.4 25.8 70.2 9.6 22.0 8.6 19.7 88.8 25.8 19.6 12.9 6.2 5.7 2.8 15.6 1.9 28.7 61.1 32.6 48.1 27.2 16.3 0.0 17.3 51.8 49.8 64.6 12.8 29.7 2.5 16.7 36.0 15.7 2.8 28.6 21.2 4.2 8.2 2.1 8.7 203.7 38.8 2.7 26.6 24.4 1.9 23.6 1.0 38.7 38.1 53.8 6.0 91.4 4.6 11.7 32.6 64.6 20.4 16.5 46.0 102.8 59.8 12.2 17.4 8.0 10.5 6.3 7.3 14.2 15.1 13.5 SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 116.6;Oligodendrocyte precursor cells: 133.2;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" 43.2 63.4 19.9 9.4 21.6 0.4 36.5 22.1 31.6 45.1 20.9 51.6 8.0 43.2 27.1 13.3 40.7 27.6 38.9 19.6 21.0 19.5 14.4 30.5 16.7 23.2 20.6 92.2 21.5 10.9 30.9 52.7 22.4 18.0 12.8 16.8 21.1 31.6 8.5 8.2 19.2 41.8 21.9 25.1 23.8 18.5 20.4 12.8 23.9 19.8 7.2 35.6 34.6 26.7 13.5 42.5 39.6 61.8 63.7 110.8 7.1 51.3 92.3 40.7 60.4 24.9 78.0 12.8 70.4 86.5 83.7 9.4 60.0 21.6 49.1 2.2 32.7 1.4 36.9 28.3 44.0 4.3 0.0 95.5 31.1 64.8 79.3 104.9 30.8 0.0 0.1 93.7 43.5 42.6 0.0 0.0 32.8 8.0 29.0 19.8 51.0 25.8 78.6 13.6 26.2 20.8 0.0 52.2 65.1 44.2 17.6 0.8 0.0 131.1 45.1 11.8 81.7 50.8 67.9 14.8 51.4 0.2 74.2 0.7 0.0 0.1 2.1 0.0 0.8 4.4 0.6 1.0 0.0 6.6 0.2 0.7 0.3 1.0 0.1 0.2 0.2 0.3 19.9 21.6 22.1 31.6 19.6 21.0 23.2 20.6 22.4 21.9 20.4 26.7 39.2 70.5 33.3 66.9 6.1 5.0 18.4 16.8 1.8 18.6 9.7 44.4 18.6 30.0 28.3 20.2 4.2 90.2 1.4 0.0 5.9 42.5 1.6 4.0 17.1 18.8 1.2 0.4 85.2 4.3 26.1 116.6 1.5 6.6 2.5 37.3 58.2 11.2 6.3 20.2 68.5 0.1 12.2 2.5 7.3 3.7 75.5 1.4 51.6 15.9 0.0 31.5 0.0 133.2 116.3 2.1 0.0 58.3 2.6 5.5 0.0 14.1 13.7 30.3 85.5 68.0 60.7 17.1 13.0 0.9 4.0 82.8 2.7 44.0 0.0 2.2 SH3D19 "DKFZp434D0215, EBP, Eve-1, EVE1, Kryn, SH3P19" ENSG00000109686 "SH3 domain containing 19" Q5HYK7 4 151102751-151325605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 263.9;Oligodendrocytes: 360.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 190.3;ASC TERT1: 161.0;HSkMC: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016424, HPA058562" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA016424: AB_1856814, HPA058562: AB_2683758" "unprognostic (1.09e-1)" "unprognostic (6.14e-2)" "unprognostic (1.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (5.09e-1)" "unprognostic (7.37e-2)" "unprognostic (1.48e-1)" "unprognostic (6.40e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.64e-2)" 70.8 15.7 9.8 12.8 14.9 0.2 31.5 6.0 9.6 22.5 104.9 44.2 44.4 23.2 10.7 40.8 23.7 63.7 64.1 6.8 11.6 27.2 49.9 36.2 5.1 8.8 10.3 42.9 15.2 19.9 5.0 27.9 8.8 27.1 48.3 12.8 17.3 40.5 17.7 30.0 49.0 41.4 5.1 7.4 22.6 12.4 11.5 3.9 25.1 33.8 7.9 33.3 20.6 18.6 26.3 19.2 12.1 9.5 190.3 161.0 26.0 31.8 34.0 13.9 14.4 24.9 31.6 0.0 12.5 29.9 22.7 19.2 12.8 36.6 13.5 0.1 10.1 0.0 22.2 26.7 46.0 0.1 0.1 129.1 27.6 20.9 32.0 23.9 81.9 0.0 0.0 0.1 36.9 10.9 0.0 0.4 24.3 40.3 27.6 0.0 0.9 0.4 17.3 18.3 0.9 16.3 22.7 23.0 18.5 24.7 7.5 0.1 59.9 43.6 15.6 19.5 12.9 0.1 0.0 0.1 22.6 0.1 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.8 14.9 6.0 9.6 6.8 11.6 8.8 10.3 8.8 5.1 11.5 18.6 36.7 22.4 32.5 8.1 2.9 28.6 14.1 12.3 18.8 6.6 20.5 25.0 88.5 34.3 29.2 16.5 14.6 25.9 5.0 103.5 5.9 11.9 4.4 17.6 38.1 29.1 18.6 7.0 55.8 15.4 20.7 77.9 38.7 13.7 21.5 37.5 21.8 46.4 7.4 6.7 30.0 35.6 10.2 4.6 20.2 6.7 62.1 4.8 26.6 74.0 1.2 20.8 5.2 263.9 360.1 21.3 55.9 48.2 3.2 41.5 88.2 27.2 52.4 11.0 13.1 46.0 26.3 2.9 6.0 16.7 38.5 27.2 5.5 20.3 54.0 41.2 SH3PXD2B "FLJ20831, KIAA1295" ENSG00000174705 "SH3 and PX domains 2B" A1X283 5 172325000-172454525 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 91.1;Leydig cells: 39.7;Oligodendrocytes: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 95.2;ASC TERT1: 79.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036471 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli fibrillar center" "HPA036471: AB_10670799" "unprognostic (3.32e-1)" "unprognostic (1.95e-2)" "unprognostic (4.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.84e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (5.38e-3)" "unprognostic (3.11e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.87e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (8.45e-4)" 22.6 25.4 9.2 11.2 12.8 0.1 19.0 12.9 11.5 36.4 9.6 14.0 2.3 32.6 5.4 10.5 17.9 18.9 7.4 9.8 10.7 2.4 2.9 17.6 3.5 14.5 12.8 18.4 9.8 6.6 5.0 8.9 16.0 12.8 5.6 3.6 18.3 13.9 3.5 19.8 11.5 23.2 10.1 6.5 13.1 6.3 13.7 4.2 8.0 3.4 3.4 18.3 18.1 15.4 1.0 14.3 52.3 34.6 95.2 79.9 44.3 8.6 29.7 5.4 10.7 4.0 1.3 0.1 11.5 33.4 16.7 8.1 18.7 9.8 5.3 0.8 3.5 0.1 13.3 2.9 30.6 0.0 36.5 51.5 15.1 22.4 6.4 5.2 37.9 3.8 0.1 0.2 24.1 3.1 0.1 4.6 20.1 8.1 3.3 17.3 8.5 5.1 5.7 1.5 4.6 29.2 6.0 3.8 10.7 16.5 1.4 2.1 40.9 33.4 13.2 20.7 3.8 0.0 0.0 0.2 22.6 2.2 27.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.8 12.9 11.5 9.8 10.7 14.5 12.8 16.0 10.1 13.7 15.4 11.3 0.0 1.1 91.1 0.4 10.1 3.2 13.9 8.6 0.6 6.2 6.5 1.8 5.7 12.0 0.0 0.0 4.5 0.2 1.3 0.0 9.9 0.9 5.5 30.8 6.4 2.4 0.0 5.0 16.0 31.0 29.8 6.1 13.4 0.0 5.8 3.3 1.8 3.1 1.7 11.2 2.1 18.3 28.4 9.4 2.0 39.7 13.6 14.2 13.1 1.3 6.3 0.0 25.1 63.0 21.8 1.0 27.1 0.0 6.9 0.2 1.9 3.8 0.3 13.1 6.0 10.5 0.8 4.2 4.7 8.1 2.2 0.5 22.3 2.7 5.7 SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 47.8;salivary gland: 51.1;skeletal muscle: 119.4;tongue: 46.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.7;Basal respiratory cells: 30.8;Club cells: 33.9;Ionocytes: 30.5;Prostatic glandular cells: 27.4;Respiratory ciliated cells: 67.1;Skeletal myocytes: 77.3;Spermatogonia: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 36.3;LHCN-M2: 142.2;RH-30: 71.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "CAB058690: AB_2665581, HPA001893: AB_1079991" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (5.09e-2)" "prognostic unfavorable (8.92e-6)" "unprognostic (1.33e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-3)" "prognostic favorable (3.94e-4)" "unprognostic (1.40e-1)" "unprognostic (9.15e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (3.06e-8)" "unprognostic (8.61e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" 5.5 0.4 0.3 0.0 0.5 0.0 1.9 0.5 1.2 15.2 1.0 0.0 0.0 0.0 0.4 1.1 0.8 0.5 0.0 0.3 0.3 0.0 0.0 1.5 0.5 0.3 0.4 0.2 0.3 47.8 19.8 0.0 0.4 13.2 0.0 0.0 51.1 0.2 119.4 0.3 0.0 0.0 0.3 0.0 0.4 1.7 0.5 9.7 1.9 46.3 0.2 1.6 0.8 0.4 15.2 3.5 0.6 28.1 17.0 20.6 0.4 4.1 10.6 4.9 4.0 0.0 8.2 0.0 2.2 0.6 2.1 4.4 10.3 6.4 2.1 0.0 17.1 2.0 1.9 6.8 0.0 0.0 0.2 15.6 4.9 2.3 0.7 36.3 0.3 1.6 5.8 0.0 142.2 2.8 0.0 0.5 0.0 0.0 8.9 0.0 71.9 0.0 5.9 16.3 2.5 0.3 5.0 0.3 6.1 0.5 3.3 0.4 13.9 6.7 5.4 7.9 6.5 0.5 0.1 0.0 1.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.2 0.3 0.3 0.3 0.4 0.4 0.3 0.5 0.4 0.8 3.2 1.5 0.0 0.0 0.1 30.7 30.8 0.6 0.0 1.0 0.8 0.9 0.0 33.9 1.8 0.0 0.2 0.0 0.1 1.9 0.0 0.2 1.1 0.1 1.6 0.0 0.0 0.0 0.8 0.4 5.7 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.5 0.0 0.0 0.6 0.0 0.3 0.0 1.9 0.0 0.8 0.0 1.0 0.1 0.2 0.0 1.2 0.0 27.4 0.0 0.1 67.1 0.2 0.0 77.3 5.1 0.0 25.0 0.1 0.1 0.3 0.1 0.1 0.0 18.3 SIX2 ENSG00000170577 "SIX homeobox 2" Q9NPC8 2 45005182-45009452 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 21.1;skeletal muscle: 33.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 6.1;Cardiomyocytes: 3.3;Fibroblasts: 3.0;Ionocytes: 8.2;Skeletal myocytes: 8.5;Smooth muscle cells: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 48.8;LHCN-M2: 46.8;RH-30: 31.9;SCLC-21H: 54.3;U-2197: 35.3;U-698: 43.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA056958 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear membrane" "HPA056958: AB_2683287" "unprognostic (1.14e-3)" "unprognostic (2.73e-2)" "unprognostic (3.09e-6)" "unprognostic (1.28e-2)" "unprognostic (3.28e-1)" "unprognostic (8.77e-2)" "unprognostic (4.06e-3)" "unprognostic (9.17e-2)" "unprognostic (1.48e-1)" "unprognostic (1.96e-1)" "unprognostic (1.02e-2)" "unprognostic (1.07e-2)" "unprognostic (4.53e-9)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-5)" "unprognostic (1.05e-1)" 10.4 0.1 0.1 0.1 0.3 0.0 1.6 0.2 0.5 11.6 0.5 0.7 0.0 1.7 0.1 0.2 0.2 0.0 1.5 0.9 0.2 0.5 0.0 0.2 0.1 0.4 1.5 0.1 6.0 2.1 12.9 0.1 1.7 6.2 0.0 0.9 21.1 1.2 33.8 0.4 0.1 0.1 0.1 0.0 9.5 0.3 0.2 3.9 0.6 15.5 0.0 1.8 8.6 0.2 0.7 0.0 0.0 4.2 13.0 48.8 0.0 0.2 2.3 1.0 0.1 0.4 0.0 0.0 2.2 0.0 0.4 0.1 4.7 8.5 0.6 0.0 2.5 0.0 16.7 0.0 0.0 0.0 4.5 2.4 0.1 10.4 0.1 0.4 1.6 0.5 0.2 0.0 46.8 1.7 0.0 2.8 0.4 0.0 10.2 0.0 31.9 0.0 0.1 2.7 54.3 0.4 7.1 0.2 0.0 0.5 0.4 4.2 0.7 0.9 2.7 35.3 0.0 1.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.5 0.9 0.2 0.4 1.5 1.7 0.1 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.9 0.4 6.1 0.0 0.0 1.2 0.6 3.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.4 0.0 0.0 0.0 2.2 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 0.0 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.5 0.0 8.5 3.2 0.0 0.4 0.0 0.9 0.0 0.0 0.2 0.0 0.2 SKI ENSG00000157933 "SKI proto-oncogene" P12755 1 2228319-2310213 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Craniosynostosis, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010449, HPA066567" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB010449: AB_2187342, HPA066567: AB_2685692" "unprognostic (3.99e-2)" "unprognostic (3.81e-2)" "unprognostic (1.44e-1)" "unprognostic (5.42e-2)" "unprognostic (4.66e-2)" "unprognostic (7.32e-2)" "unprognostic (1.88e-1)" "unprognostic (9.14e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "unprognostic (4.94e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-3)" "unprognostic (1.88e-1)" "unprognostic (7.82e-2)" "unprognostic (9.69e-2)" "unprognostic (5.24e-3)" 38.3 14.3 22.0 14.1 20.9 11.5 31.5 59.5 24.2 37.5 3.4 34.6 9.3 42.0 8.3 23.5 34.1 14.6 34.4 24.1 11.0 23.6 24.3 33.9 11.6 20.1 16.9 36.4 13.1 7.3 23.0 13.9 17.2 26.8 7.0 5.1 25.2 19.8 22.1 38.6 24.1 16.8 17.1 22.9 22.6 13.2 19.4 8.7 25.4 11.7 10.2 30.8 29.2 15.7 18.3 10.4 24.5 23.9 40.0 23.8 16.1 26.7 14.8 16.3 11.9 15.8 13.7 11.5 19.5 34.4 6.8 21.0 13.8 21.6 15.0 12.7 30.0 29.0 16.4 22.5 26.7 16.5 29.8 25.8 11.8 24.5 18.2 30.0 20.2 4.8 16.6 8.6 20.2 11.6 2.0 18.1 24.8 12.0 19.8 9.1 15.5 9.6 13.9 7.0 35.0 22.9 26.0 22.9 26.7 15.6 7.7 20.9 36.9 27.7 17.5 39.6 21.1 6.7 5.2 10.5 14.8 28.2 11.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 22.0 20.9 59.5 24.2 24.1 11.0 20.1 16.9 17.2 17.1 19.4 15.7 44.2 9.6 12.6 18.9 18.8 47.0 13.1 7.0 32.5 8.9 20.3 25.8 12.7 11.5 6.7 7.3 0.0 7.3 32.2 7.3 1.9 8.2 0.8 10.1 28.9 34.3 6.0 14.7 22.6 6.9 15.5 35.5 9.7 18.5 13.3 6.4 33.9 23.0 13.7 11.8 24.1 14.3 0.0 16.4 29.5 5.0 49.7 28.9 16.0 48.7 9.4 11.1 12.3 11.6 11.4 13.0 9.4 55.3 16.9 14.9 8.1 6.0 4.0 4.4 46.0 36.2 37.3 4.7 12.8 32.2 45.0 16.3 33.4 6.7 10.7 11.4 SLC19A2 "THTR1, TRMA" ENSG00000117479 "Solute carrier family 19 member 2" O60779 1 169463909-169485944 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 124.1;tongue: 84.9" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 84.5;Syncytiotrophoblasts: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006119, HPA016599" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA006119: AB_1079996, HPA016599: AB_1857005" "prognostic favorable (8.41e-4)" "unprognostic (8.82e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-3)" "prognostic favorable (2.90e-4)" "unprognostic (4.45e-2)" "unprognostic (9.69e-2)" "unprognostic (1.45e-1)" "unprognostic (2.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (3.60e-2)" "unprognostic (2.14e-2)" 42.2 17.8 3.0 8.3 3.1 8.7 20.9 5.1 4.2 10.5 9.3 11.8 3.5 8.6 6.1 11.3 21.3 25.8 31.2 4.0 3.6 13.0 37.1 19.5 2.6 4.9 3.7 20.5 22.2 24.8 19.0 18.1 4.0 10.5 4.3 7.5 12.5 3.8 124.1 16.5 11.4 6.1 3.7 2.8 19.2 7.8 4.2 4.1 15.7 84.9 2.8 18.1 12.9 3.5 7.4 5.1 11.4 9.0 34.4 12.7 25.0 5.8 4.3 4.6 6.5 20.9 7.6 6.5 6.4 3.9 8.5 7.7 13.9 8.5 5.1 18.8 13.0 6.2 16.7 19.3 18.7 15.8 5.9 15.0 12.2 7.4 18.8 6.4 7.0 11.3 25.3 4.1 7.9 5.0 8.2 7.1 25.8 14.1 7.7 0.0 24.6 7.5 12.2 15.5 9.9 13.3 8.0 13.6 29.2 12.8 8.5 10.1 5.8 5.5 7.7 6.9 11.4 5.6 5.6 2.1 8.1 6.0 7.4 0.0 0.6 1.1 0.3 0.2 1.1 0.4 0.4 0.7 0.7 0.4 1.0 1.0 0.4 0.9 2.0 0.2 0.3 0.2 3.0 3.1 5.1 4.2 4.0 3.6 4.9 3.7 4.0 3.7 4.2 3.5 13.6 9.6 19.3 11.8 7.3 29.6 16.5 4.4 43.9 5.3 34.1 13.6 27.7 7.2 11.4 5.5 2.1 26.9 11.3 10.6 0.0 7.4 4.3 22.6 9.7 3.7 9.0 5.2 15.6 5.3 4.5 52.7 49.5 42.7 10.2 4.1 1.1 29.8 7.0 6.7 22.8 6.4 12.2 2.9 8.8 2.7 6.8 18.3 21.4 7.5 1.0 2.5 2.1 16.1 3.3 9.6 5.4 4.9 14.0 16.5 5.6 2.0 12.7 5.1 0.0 84.5 14.2 6.7 4.1 35.2 50.4 156.4 7.5 3.1 6.7 28.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 149.8;Leydig cells: 321.8;Peritubular cells: 769.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.1;EFO-21: 2.8;RPMI-8226: 11.3;RPTEC TERT1: 3.8;SuSa: 9.1" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in single" "spinal cord: 1.4" "Secreted to extracellular matrix" NA NA 120000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-1)" "unprognostic (5.29e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (6.20e-3)" 67.8 14.0 10.6 13.0 12.7 0.0 61.0 10.8 16.2 82.1 42.3 44.1 21.4 164.0 147.2 53.1 119.6 100.8 57.2 10.6 11.3 13.0 4.0 14.7 14.7 11.8 11.8 124.1 25.2 12.2 4.5 18.8 11.9 31.0 24.9 2.8 17.1 54.6 42.1 28.9 27.8 76.5 10.2 4.4 144.7 44.2 12.2 10.9 43.5 54.8 11.1 68.7 21.8 10.0 2.4 0.0 8.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.4 1.0 0.0 0.0 0.0 0.0 11.3 3.8 0.0 1.7 0.3 0.0 0.3 0.1 9.1 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 12.7 10.8 16.2 10.6 11.3 11.8 11.8 11.9 10.2 12.2 10.0 8.1 0.0 1.7 0.7 0.0 11.1 8.0 0.0 1.2 7.1 12.5 12.1 7.7 0.0 1.8 11.0 0.0 2.5 0.0 3.6 0.0 0.0 2.6 40.3 42.3 11.0 19.7 0.0 0.5 0.0 1.7 149.8 1.1 58.4 0.0 17.2 3.3 0.0 1.2 0.0 9.7 4.5 0.0 0.0 3.9 17.2 321.8 2.9 3.6 6.5 0.0 0.4 0.0 2.0 0.1 0.1 0.4 769.2 0.1 6.7 2.0 0.0 2.2 0.8 46.0 14.7 63.3 3.9 5.1 0.8 2.7 2.6 1.7 17.3 47.4 1.1 SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542282-64662307 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 221.1;HBF TERT88: 157.4;LHCN-M2: 164.1;TIME: 207.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA071508: AB_2686406" "unprognostic (1.21e-1)" "unprognostic (2.07e-2)" "unprognostic (1.59e-2)" "unprognostic (3.24e-1)" "unprognostic (6.19e-2)" "unprognostic (7.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.50e-1)" "unprognostic (7.94e-2)" "unprognostic (1.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.54e-1)" "unprognostic (5.55e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" 6.8 4.3 3.3 6.2 3.9 5.9 5.2 5.3 3.4 7.3 3.4 5.3 6.9 5.9 2.3 4.4 5.8 7.1 4.1 3.1 3.3 7.0 3.8 10.5 5.0 4.6 2.7 4.8 6.5 6.3 3.4 13.3 2.8 7.4 4.8 12.5 6.2 5.2 3.0 5.0 10.1 6.1 3.2 5.4 7.8 13.0 3.6 7.8 8.3 6.2 6.5 7.5 3.2 3.8 67.0 17.8 15.3 9.1 11.0 41.5 7.6 221.1 103.2 88.2 73.4 10.4 45.5 8.6 14.5 38.8 29.9 15.2 16.0 37.2 157.4 4.3 12.9 9.1 10.9 11.8 12.0 12.2 5.5 11.8 16.1 109.5 48.5 52.7 97.0 11.9 13.0 7.5 164.1 13.2 28.3 4.8 9.9 8.8 23.8 6.1 38.4 5.2 20.1 11.1 16.0 17.9 14.4 5.8 10.0 24.6 11.7 8.4 207.6 93.8 44.4 39.2 139.6 10.4 11.7 13.9 23.7 7.3 28.4 1.0 0.6 1.4 1.0 0.4 1.1 0.7 0.8 1.1 0.7 0.9 0.9 0.9 1.4 2.7 0.3 0.6 0.2 0.5 3.3 3.9 5.3 3.4 3.1 3.3 4.6 2.7 2.8 3.2 3.6 3.8 40.2 32.1 26.0 96.3 18.6 43.8 30.8 10.0 25.0 26.4 23.3 18.7 10.3 7.2 16.1 9.2 43.8 13.2 35.4 13.8 9.8 18.1 29.0 29.0 37.2 39.3 17.9 2.5 46.1 10.0 3.6 28.1 12.2 39.7 13.3 21.4 38.2 5.1 13.6 26.9 40.9 11.2 10.2 17.3 25.5 9.2 12.5 22.8 21.4 101.2 13.2 21.4 20.6 101.0 52.8 26.5 24.7 12.0 18.0 25.2 28.0 9.6 14.4 46.7 0.0 37.4 23.3 37.1 21.3 13.7 39.8 7.3 33.5 16.2 13.8 24.6 SMYD4 "KIAA1936, ZMYND21" ENSG00000186532 "SET and MYND domain containing 4" Q8IYR2 17 1779485-1830634 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030059 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA030059: AB_2191728" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (2.47e-1)" "unprognostic (4.23e-2)" "unprognostic (1.13e-2)" "unprognostic (3.66e-2)" "unprognostic (4.03e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-3)" "unprognostic (9.26e-3)" "unprognostic (3.63e-2)" "unprognostic (1.33e-2)" "unprognostic (7.35e-2)" "unprognostic (1.52e-1)" "unprognostic (1.18e-1)" 7.4 6.6 4.1 6.0 3.6 3.4 7.3 8.0 4.5 7.9 3.7 7.5 7.0 6.5 5.0 3.9 7.3 3.6 7.0 3.5 3.5 3.7 4.9 5.6 6.8 3.7 3.2 9.5 6.7 3.6 6.6 4.7 4.0 6.5 4.8 7.6 7.3 5.6 13.7 6.6 7.4 5.9 2.2 6.3 4.9 5.8 4.3 6.2 5.7 10.2 6.5 7.2 6.2 5.6 7.4 13.7 13.5 9.6 9.0 6.1 15.7 11.9 6.7 12.3 12.5 22.0 6.2 19.7 7.8 4.8 8.3 14.2 12.9 7.7 15.3 5.7 13.1 7.2 15.9 6.0 4.5 7.4 6.8 4.4 6.8 12.7 11.1 6.3 6.2 16.6 7.6 7.5 9.7 4.6 13.6 5.3 6.2 8.7 6.6 16.7 6.9 5.0 4.9 8.8 5.5 7.6 11.0 4.5 11.1 10.9 6.7 4.5 5.9 12.0 6.1 10.0 10.4 5.2 7.5 7.1 6.8 6.4 11.9 12.0 2.4 2.3 5.1 3.0 4.3 4.0 3.0 3.3 1.5 2.7 3.4 5.0 1.3 3.1 2.4 4.5 3.5 2.1 4.1 3.6 8.0 4.5 3.5 3.5 3.7 3.2 4.0 2.2 4.3 5.6 22.9 6.4 27.8 6.5 12.9 5.0 9.3 11.9 14.8 19.3 6.9 8.4 6.3 14.3 14.0 7.3 33.3 9.7 16.5 6.9 1.9 5.7 20.2 3.7 8.9 10.9 3.6 9.7 11.7 3.3 10.9 14.2 4.1 3.5 7.6 14.7 17.2 6.7 12.9 26.9 12.1 5.2 12.2 23.3 9.2 5.9 27.1 17.4 5.4 13.1 16.4 7.9 43.3 4.5 7.1 4.2 2.0 24.8 10.1 7.2 23.3 2.9 17.8 19.9 46.0 43.6 23.9 12.6 14.8 5.1 6.7 8.1 12.1 6.1 6.4 3.5 SNX21 "C20orf161, dJ337O18.4, SNX-L" ENSG00000124104 "Sorting nexin family member 21" Q969T3 20 45833799-45843276 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Theca cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.8;classical monocyte: 1.6;eosinophil: 4.8;intermediate monocyte: 2.6;non-classical monocyte: 2.0" "Group enriched" "Detected in many" 8 "granulocytes: 4.8;monocytes: 2.6" "Cell line enhanced" "Detected in many" "EFO-21: 17.9;PC-3: 29.8;U-87 MG: 18.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046359 Approved Approved "Vesicles,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Centriolar satellite" "HPA046359: AB_10963216" "unprognostic (1.97e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (4.16e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (4.96e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-2)" "unprognostic (2.18e-1)" 25.0 27.8 4.9 1.1 4.1 0.7 18.7 5.8 7.9 26.4 4.9 15.8 3.7 28.6 0.8 14.1 24.6 5.0 14.9 3.5 2.8 11.9 6.2 10.9 1.3 9.2 5.1 30.5 4.2 3.3 10.9 2.9 6.5 14.4 1.2 0.7 9.7 4.8 31.9 47.9 7.5 1.9 3.0 7.3 11.3 6.1 7.2 0.5 9.1 6.7 0.6 25.7 19.5 4.6 4.3 6.7 1.0 6.5 7.8 7.5 4.3 6.8 5.0 5.0 4.0 5.0 3.0 0.1 17.9 4.8 4.1 5.5 0.2 4.5 0.8 0.3 1.4 0.1 4.1 4.6 3.3 0.0 1.3 3.9 2.7 4.8 0.4 1.7 3.6 1.1 0.1 0.0 0.9 11.1 0.1 0.8 1.8 0.8 29.8 0.1 0.5 0.2 1.0 0.7 1.2 11.6 14.6 10.3 8.1 0.8 5.9 1.2 6.4 6.0 7.2 17.2 5.5 0.2 0.9 0.2 18.1 0.0 4.4 2.8 1.6 4.8 0.0 2.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 2.0 0.1 0.4 0.3 4.9 4.1 5.8 7.9 3.5 2.8 9.2 5.1 6.5 3.0 7.2 4.6 11.1 9.6 8.3 25.1 1.0 10.1 4.7 6.4 8.6 18.4 8.6 8.5 4.8 7.2 10.3 5.5 8.4 4.9 0.4 10.3 25.4 10.3 3.7 5.0 27.0 10.3 9.0 0.0 4.8 11.7 5.2 37.0 6.6 7.5 0.0 27.0 10.4 4.3 4.8 15.2 5.7 9.2 4.1 7.1 10.0 18.3 19.6 5.4 10.6 3.7 3.3 14.8 1.0 8.5 6.5 8.4 5.9 17.0 0.8 3.7 15.9 15.7 6.6 15.6 6.6 16.4 20.1 0.9 2.4 4.1 22.7 2.5 2.2 62.2 7.0 3.4 SNX33 "MGC32065, SH3PX3, SH3PXD3C, SNX30" ENSG00000173548 "Sorting nexin 33" Q8WV41 15 75647912-75662301 "Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040988 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "HPA040988: AB_10794983" "unprognostic (1.83e-2)" "unprognostic (2.75e-2)" "unprognostic (1.09e-2)" "unprognostic (1.94e-3)" "unprognostic (1.73e-1)" "unprognostic (3.18e-1)" "unprognostic (2.51e-2)" "unprognostic (9.93e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (5.00e-3)" "unprognostic (3.00e-2)" "unprognostic (5.23e-3)" "unprognostic (5.99e-2)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (8.54e-2)" 26.2 17.2 11.1 7.1 11.1 0.5 21.3 9.5 9.8 29.3 11.8 19.7 12.1 23.6 8.4 42.5 21.9 14.3 19.6 10.2 9.9 12.5 29.0 19.3 8.2 14.2 10.8 25.6 27.2 11.1 7.0 11.9 10.3 23.5 10.0 1.6 20.6 16.6 5.9 29.6 15.5 14.6 10.1 11.8 18.8 3.5 13.0 7.6 16.7 9.2 10.6 20.2 30.2 9.1 14.9 13.1 12.6 13.5 48.7 31.5 13.9 14.3 29.8 15.6 14.2 8.3 15.3 0.4 10.3 31.7 22.3 35.1 15.7 37.4 8.3 16.4 5.3 4.6 15.5 15.2 32.3 0.4 4.7 32.6 44.5 15.2 21.2 37.4 10.0 1.4 11.0 2.0 18.4 2.9 0.1 9.4 12.1 9.3 7.3 2.3 9.9 0.7 15.9 22.1 1.1 8.6 21.1 22.7 17.4 23.4 13.6 10.5 14.6 22.1 10.4 16.6 7.7 0.3 0.4 0.1 22.3 5.4 6.0 0.0 0.5 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 11.1 11.1 9.5 9.8 10.2 9.9 14.2 10.8 10.3 10.1 13.0 9.1 8.3 6.4 5.6 2.9 0.2 12.1 3.4 9.3 6.2 0.0 6.8 5.7 3.8 2.8 8.2 7.3 2.1 3.1 1.2 13.5 0.0 7.5 0.3 4.8 7.5 5.7 9.1 0.4 0.5 6.5 4.1 13.3 14.3 4.8 1.3 6.8 10.0 12.6 5.1 0.0 0.1 8.1 8.2 2.8 7.8 0.6 13.1 2.9 3.6 2.8 3.0 3.8 0.0 2.5 0.2 15.9 7.6 15.1 1.1 7.5 12.4 3.7 9.5 0.2 19.7 8.5 9.5 0.1 0.6 5.5 11.2 1.4 1.8 2.5 7.3 11.3 SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 436.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 498.5;Leydig cells: 424.1;Peritubular cells: 365.6;Smooth muscle cells: 428.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.2;BJ: 38.1;PC-3: 55.1;RPTEC TERT1: 231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" NA NA 50400000 510000000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA042110: AB_2677850" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" 221.4 20.4 14.3 26.1 20.9 0.0 134.2 15.8 23.8 226.5 436.1 122.7 18.2 151.6 10.4 62.1 177.6 22.4 150.1 47.1 14.1 124.1 16.5 155.0 10.6 22.9 23.4 59.7 86.7 2.6 19.8 39.8 17.5 131.3 13.4 1.9 70.9 23.4 22.0 91.9 65.2 37.1 16.4 24.8 102.1 74.1 19.0 5.8 176.6 22.9 7.0 178.3 170.4 13.6 0.0 0.0 0.0 0.0 66.2 17.3 2.0 38.1 16.7 2.3 1.4 0.5 0.0 0.0 11.8 8.0 0.1 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.0 16.8 0.0 15.8 0.0 17.9 0.1 0.0 1.1 0.0 0.0 0.1 0.3 1.1 8.0 0.0 55.1 0.0 0.0 0.6 231.3 0.8 0.2 0.2 0.0 1.2 0.0 2.1 32.8 0.0 0.0 8.7 1.0 1.6 0.4 0.1 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 20.9 15.8 23.8 47.1 14.1 22.9 23.4 17.5 16.4 19.0 13.6 46.1 12.8 18.1 7.2 1.0 90.8 65.5 0.6 10.2 0.4 21.7 22.1 23.0 144.4 7.6 90.1 0.0 211.4 1.8 25.6 15.6 63.6 18.7 81.9 45.8 21.0 34.6 0.0 0.1 1.8 17.0 498.5 5.1 80.3 0.0 0.1 15.4 0.2 17.3 0.0 0.1 51.9 0.0 0.3 115.5 33.9 424.1 3.2 80.0 3.7 0.0 20.7 0.0 0.5 0.7 3.5 89.3 365.6 1.1 80.4 0.0 142.7 0.1 1.4 197.2 6.5 428.9 73.2 4.4 6.1 70.3 190.0 7.6 6.1 51.8 9.6 SOX11 ENSG00000176887 "SRY-box transcription factor 11" P35716 2 5692384-5701385 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.4;Breast myoepithelial cells: 8.6;Cardiomyocytes: 13.9;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 21.6;Skeletal myocytes: 38.8" "Cancer enhanced" "Detected in many" "glioma: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 47.2;NTERA-2: 23.6;REH: 17.9;RH-30: 18.2;SCLC-21H: 29.1;SH-SY5Y: 44.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000448, HPA000536, CAB056152, CAB056153" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB056152: AB_2665567, CAB056153: AB_2665568, HPA000448: , HPA000536: AB_1080060" "unprognostic (2.17e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-2)" "unprognostic (7.35e-6)" "unprognostic (2.79e-1)" "unprognostic (1.19e-1)" "unprognostic (4.04e-8)" "unprognostic (2.79e-2)" "unprognostic (7.27e-2)" "unprognostic (3.17e-1)" "unprognostic (3.35e-3)" "unprognostic (2.42e-1)" "unprognostic (8.45e-8)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-3)" "unprognostic (7.47e-2)" 0.0 0.0 2.3 0.0 2.8 0.0 0.0 1.3 1.9 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 5.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.2 3.2 0.1 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 4.4 0.0 0.0 0.0 23.6 0.0 0.0 17.9 18.2 0.7 0.0 0.0 29.1 44.0 0.0 0.3 0.0 8.2 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.3 0.6 1.2 0.0 0.0 11.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.1 2.3 2.8 1.3 1.9 1.3 5.0 2.5 2.9 2.0 3.2 4.6 3.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.1 6.4 8.6 13.9 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 5.7 0.9 0.0 0.8 1.2 0.0 0.0 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 1.0 0.0 0.5 0.0 21.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 38.8 1.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.0 0.0 SP5 ENSG00000204335 "Sp5 transcription factor" Q6BEB4 2 170715337-170718078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 8.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.8;Cardiomyocytes: 3.1;Distal tubular cells: 3.9;Endometrial stromal cells: 7.1;Fibroblasts: 4.4;Intestinal goblet cells: 4.3;Spermatogonia: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 122.1" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Low region specificity" "Detected in some" HPA074123 Approved Nucleoplasm,Nucleoli NA NA "Cluster 31: Skin - Epidermis development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA074123: AB_2686664" "unprognostic (1.16e-2)" "unprognostic (6.99e-2)" "unprognostic (3.41e-2)" "unprognostic (2.10e-2)" "unprognostic (1.14e-1)" "unprognostic (9.52e-3)" "unprognostic (1.45e-1)" "unprognostic (4.60e-2)" "unprognostic (4.77e-1)" "unprognostic (8.97e-3)" "unprognostic (1.79e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-8)" "unprognostic (8.05e-3)" "unprognostic (2.49e-1)" "unprognostic (2.41e-2)" "unprognostic (2.17e-1)" 2.5 1.2 0.5 0.2 0.5 0.0 1.4 2.2 0.3 8.8 0.5 1.5 1.0 3.7 0.4 1.2 1.2 0.2 0.2 0.2 1.4 0.2 2.1 0.5 0.2 0.3 1.4 0.4 0.4 0.3 0.1 0.2 0.2 1.7 0.2 0.0 1.5 0.2 0.2 4.6 1.4 0.1 0.0 0.0 3.1 0.8 1.8 0.1 0.1 0.0 0.8 1.5 2.2 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 27.7 0.1 0.0 0.5 0.0 0.5 1.5 0.3 0.0 0.0 3.5 0.3 0.4 0.1 122.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 2.0 2.3 0.0 0.0 0.0 0.1 0.0 0.1 0.3 4.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 2.2 0.3 0.2 1.4 0.3 1.4 0.2 0.0 1.8 0.2 0.2 0.0 0.0 0.3 0.0 0.8 0.1 0.0 2.8 0.0 0.2 0.3 3.1 0.0 0.0 1.8 0.0 1.5 0.1 0.3 3.9 0.0 0.2 2.3 7.1 0.5 0.0 0.0 0.0 0.0 0.0 4.4 0.0 1.3 0.0 0.0 0.0 2.5 0.2 0.0 0.4 4.3 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.4 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.7 0.2 0.1 0.3 0.2 0.0 1.6 0.0 SPRY2 hSPRY2 ENSG00000136158 "Sprouty RTK signaling antagonist 2" O43597 13 80335976-80341126 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 267.9;SK-MEL-30: 156.9;WM-115: 136.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037205, HPA042198" Approved Supported "Actin filaments,Microtubules" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments, Microtubules" "CAB037205: AB_261923, HPA042198: AB_2677896" "unprognostic (9.37e-3)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (9.12e-3)" "unprognostic (3.80e-2)" "unprognostic (8.99e-2)" "unprognostic (3.95e-3)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (4.28e-2)" "unprognostic (1.56e-2)" "unprognostic (9.89e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.86e-2)" 69.6 24.1 37.4 11.8 38.0 29.5 66.2 57.6 42.9 31.0 27.7 40.4 17.6 29.3 15.3 20.0 46.7 30.1 50.9 38.5 36.0 21.1 27.8 31.5 8.9 50.2 40.4 16.9 27.4 10.2 17.3 13.9 40.2 26.2 27.3 34.2 34.8 18.9 39.1 26.5 25.4 23.5 42.0 30.8 25.9 4.1 39.7 11.3 27.1 41.4 4.9 27.0 30.8 43.4 1.8 7.6 84.2 267.9 108.4 70.6 5.8 69.3 31.1 15.3 18.2 34.9 10.3 0.0 11.6 28.5 10.6 6.7 4.8 13.9 17.0 0.1 15.3 12.0 4.5 8.9 24.9 63.4 4.8 31.8 14.6 26.1 63.3 95.6 29.9 13.0 4.4 0.3 35.0 1.5 8.6 28.8 33.7 23.6 19.6 25.6 112.0 0.2 28.8 11.7 1.0 46.7 5.7 3.1 156.9 32.9 6.3 56.0 44.3 14.3 5.6 30.3 13.6 0.1 0.1 0.0 97.6 23.9 136.9 0.0 0.0 2.1 0.3 0.0 0.1 0.4 0.0 0.8 0.9 0.0 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.1 37.4 38.0 57.6 42.9 38.5 36.0 50.2 40.4 40.2 42.0 39.7 43.4 48.5 25.6 29.3 59.4 2.9 43.5 38.0 12.5 53.5 5.9 12.4 21.3 20.5 18.6 6.3 1.8 6.2 8.7 12.1 33.4 5.9 11.3 0.3 25.2 17.6 22.3 12.0 8.4 22.1 8.0 2.9 65.9 11.2 41.7 16.4 7.2 32.5 17.0 10.9 8.4 15.3 36.1 4.1 27.3 10.7 1.5 29.5 12.2 14.2 15.9 0.8 68.5 3.1 39.7 17.6 18.0 33.7 5.7 1.7 23.1 7.2 8.3 4.8 23.3 26.3 57.7 67.6 0.1 1.5 16.2 29.1 9.6 11.1 8.5 27.6 11.9 SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: AB_10673358, HPA039685: AB_2676623" "unprognostic (7.73e-3)" "unprognostic (6.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.27e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.78e-15)" "unprognostic (9.82e-2)" "unprognostic (5.27e-2)" "unprognostic (7.44e-3)" "unprognostic (1.41e-1)" 32.2 29.2 70.6 18.4 77.9 6.4 30.2 35.6 84.2 33.6 38.1 32.8 18.9 38.1 36.2 31.7 45.1 20.4 42.4 79.9 60.4 29.5 22.1 23.6 17.4 61.7 55.1 43.5 50.0 43.3 60.7 14.0 61.5 34.5 17.0 39.3 43.9 40.6 21.2 27.0 23.4 31.6 43.8 24.3 35.8 11.5 58.0 13.7 34.6 23.1 20.6 36.5 30.7 67.9 28.4 43.0 5.6 11.5 45.4 22.4 7.3 42.6 22.2 16.1 10.1 7.4 23.8 18.6 34.2 53.5 19.2 26.0 7.6 32.9 10.5 19.4 11.3 11.5 25.5 16.9 34.0 22.3 20.1 20.2 51.6 23.1 34.9 31.6 33.5 9.3 10.4 45.3 28.5 62.3 16.3 11.7 3.2 23.1 30.8 7.1 9.5 38.4 20.6 22.3 9.4 8.9 37.3 34.6 18.1 3.0 31.8 16.7 46.4 18.1 17.9 40.9 29.0 24.7 24.1 5.4 53.8 19.5 22.4 29.9 16.7 47.5 32.7 28.9 30.9 14.6 22.4 26.9 15.5 11.3 18.8 22.7 25.8 17.0 32.8 7.4 13.5 28.9 70.6 77.9 35.6 84.2 79.9 60.4 61.7 55.1 61.5 43.8 58.0 67.9 13.4 3.2 10.1 4.9 13.3 5.7 19.5 12.0 13.1 46.4 11.3 8.8 20.4 17.2 10.4 18.4 8.4 6.2 8.8 9.1 11.7 30.4 0.9 21.2 10.9 17.1 11.5 2.1 14.4 36.5 14.6 22.9 15.8 16.1 10.1 5.1 18.9 9.1 11.8 43.7 13.5 13.8 10.2 11.7 5.7 2.7 16.1 10.3 10.6 3.7 15.0 38.5 16.5 4.5 5.6 28.6 9.3 33.1 19.1 20.8 10.7 15.6 18.2 23.8 19.7 11.1 20.0 4.5 3.9 12.0 9.5 4.2 14.9 5.1 7.9 16.4 SPSB1 SSB-1 ENSG00000171621 "SplA/ryanodine receptor domain and SOCS box containing 1" Q96BD6 1 9292894-9369532 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 79.5;Proximal enterocytes: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 81.5;SK-MEL-30: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.23e-2)" "unprognostic (8.91e-2)" "unprognostic (1.56e-1)" "unprognostic (2.85e-1)" "unprognostic (4.18e-2)" "unprognostic (2.88e-1)" "unprognostic (2.02e-2)" "unprognostic (1.24e-1)" "unprognostic (3.84e-2)" "unprognostic (2.54e-2)" "unprognostic (6.86e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.08e-6)" "unprognostic (3.95e-2)" "unprognostic (3.49e-1)" "unprognostic (1.35e-2)" "unprognostic (2.24e-2)" 53.3 9.7 7.8 14.4 14.2 1.4 25.1 12.9 10.2 30.7 5.1 23.3 19.6 47.0 3.8 26.7 23.4 29.1 20.1 9.4 10.9 16.9 48.1 28.7 9.3 22.8 15.0 24.1 30.6 20.4 10.2 10.7 15.4 18.1 8.7 2.0 15.7 10.0 44.2 25.3 30.0 26.1 12.1 3.6 17.9 8.3 15.5 10.3 20.3 32.3 12.1 33.0 21.7 19.7 16.2 14.6 1.1 3.2 42.4 20.2 26.6 10.7 35.4 21.0 16.6 15.8 23.2 0.4 21.5 16.4 25.0 23.9 4.8 19.4 13.8 58.2 3.8 0.0 19.6 17.5 27.1 0.1 1.4 21.1 38.3 81.5 10.4 20.8 30.9 3.2 1.9 42.1 17.3 6.0 9.0 0.6 2.3 11.1 15.5 3.1 6.4 5.1 17.9 10.9 3.9 1.1 17.1 45.8 71.4 28.4 1.2 5.3 25.8 15.2 18.9 24.0 9.9 17.7 27.3 5.6 27.5 2.0 16.7 1.2 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.8 0.2 7.8 14.2 12.9 10.2 9.4 10.9 22.8 15.0 15.4 12.1 15.5 19.7 19.4 19.2 5.3 2.6 6.5 69.0 47.0 11.8 25.6 0.6 26.9 17.8 4.1 24.3 11.5 3.7 2.1 1.1 3.2 19.9 3.9 25.0 0.8 42.2 30.3 20.6 6.6 0.4 2.1 32.0 12.0 67.0 4.1 79.5 14.0 30.7 13.2 21.6 3.1 11.8 1.7 7.7 2.0 0.9 27.7 1.8 11.8 8.2 49.8 3.7 3.3 2.2 0.0 18.1 22.8 33.7 15.6 8.2 8.4 28.4 83.1 5.5 20.7 0.6 6.6 40.7 22.9 0.4 3.2 57.0 70.8 2.2 8.1 0.5 11.4 63.1 SRPX2 SRPUL ENSG00000102359 "Sushi repeat containing protein X-linked 2" O60687 X 100644195-100675788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.8" "Cell type enhanced" "Detected in many" "Adipocytes: 20.9;Fibroblasts: 34.3;Granulosa cells: 21.6;Microglial cells: 37.5;Skeletal myocytes: 17.5;Urothelial cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 282.3;ASC TERT1: 116.9;HSkMC: 103.3;HUVEC TERT2: 72.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 2.8" HPA038786 Approved "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038786: AB_10672724" "unprognostic (4.10e-2)" "unprognostic (4.55e-2)" "unprognostic (2.08e-1)" "unprognostic (3.72e-2)" "unprognostic (1.96e-1)" "unprognostic (4.21e-3)" "unprognostic (3.59e-3)" "unprognostic (5.41e-2)" "unprognostic (3.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.86e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-3)" "unprognostic (1.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.85e-1)" 31.8 7.5 3.6 6.3 4.5 0.2 20.7 1.3 2.6 11.3 8.5 7.1 1.2 6.0 0.9 17.7 7.1 3.1 12.7 2.8 5.8 13.9 5.4 13.8 0.4 4.3 5.6 8.3 2.9 0.7 2.5 9.3 3.1 6.3 1.8 0.1 4.6 3.8 3.4 3.7 5.1 4.4 2.0 12.9 4.5 1.1 7.4 0.3 4.3 4.8 1.2 16.8 10.9 2.5 11.7 1.2 2.9 0.1 282.3 116.9 0.0 26.3 19.8 8.0 25.1 1.4 17.6 0.0 1.1 15.9 7.5 0.7 0.2 13.1 8.6 0.1 0.1 0.2 0.9 2.8 29.3 0.2 0.6 103.3 0.3 27.8 0.9 24.6 72.7 0.0 0.0 0.1 27.1 0.0 0.0 0.0 3.4 0.2 0.3 0.0 2.5 0.0 11.4 37.6 0.4 0.0 0.0 0.8 0.2 6.1 0.3 0.1 36.7 13.8 12.3 10.3 0.9 0.1 0.0 0.1 18.3 0.0 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.5 1.3 2.6 2.8 5.8 4.3 5.6 3.1 2.0 7.4 2.5 20.9 0.0 0.6 10.1 0.3 0.4 5.0 6.5 0.6 0.0 4.8 1.8 0.9 0.0 13.7 0.0 0.0 0.2 0.0 1.9 0.0 1.6 3.6 0.6 11.2 1.6 0.0 0.0 0.4 0.0 0.4 34.3 1.1 0.4 0.0 21.6 4.6 0.2 0.9 0.0 0.2 0.1 4.1 0.3 1.6 2.7 15.8 0.3 0.0 37.5 0.0 0.0 0.0 2.0 0.1 0.8 0.0 6.0 0.2 1.6 0.0 0.1 15.5 0.0 0.0 17.5 14.6 0.2 0.1 0.6 0.4 0.5 0.3 2.6 0.4 49.1 SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.3;Fibroblasts: 27.0;Leydig cells: 18.0;Peritubular cells: 15.8;Skeletal myocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 26.9;BJ: 22.7;fHDF/TERT166: 27.5;hTERT-RPE1: 23.2;U-87 MG: 27.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" 13.1 2.2 2.6 3.6 4.6 0.1 8.8 3.0 2.1 23.0 1.8 33.6 1.9 39.7 3.9 5.7 17.0 12.9 17.6 1.8 2.1 3.6 1.7 9.1 1.3 3.9 2.6 14.5 1.8 0.3 17.6 1.9 4.0 8.8 2.8 1.1 3.4 12.8 3.6 5.6 8.7 20.1 2.2 11.1 9.8 2.6 3.6 2.0 3.8 2.8 0.5 10.6 15.9 2.1 0.1 1.4 0.5 0.0 3.3 26.9 0.0 22.7 5.5 3.7 4.6 0.4 0.0 1.2 0.3 27.5 1.1 0.0 0.0 0.0 1.9 0.1 0.3 5.6 1.5 0.0 5.2 0.1 9.6 12.3 0.0 5.4 0.0 23.2 0.0 0.7 0.2 0.3 0.6 0.1 0.1 0.5 0.9 0.0 0.2 0.7 1.2 0.3 2.5 0.0 2.9 0.4 0.4 0.0 0.5 0.5 0.4 1.2 7.9 1.0 1.3 1.1 3.8 0.4 0.0 0.1 27.8 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.6 3.0 2.1 1.8 2.1 3.9 2.6 4.0 2.2 3.6 2.1 3.5 3.2 0.6 4.2 0.3 1.9 0.3 0.3 0.0 5.3 0.8 1.1 2.8 0.0 0.1 0.0 2.1 0.1 0.4 0.8 1.9 0.1 0.6 1.5 19.3 3.3 0.0 0.0 1.5 0.0 0.1 27.0 2.0 0.9 0.0 0.5 2.2 0.0 1.2 3.3 1.1 0.4 0.0 1.0 3.8 1.3 18.0 2.0 1.8 2.8 0.7 2.1 0.0 0.0 0.3 0.1 0.3 15.8 0.3 0.3 4.6 0.2 0.7 1.9 0.0 32.1 6.8 0.9 1.1 0.4 1.8 0.0 0.5 0.9 1.4 0.2 SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 79.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 140.8;Leydig cells: 185.8;Peritubular cells: 267.4;Skeletal myocytes: 139.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.4;naive B-cell: 16.9" "Lineage enriched" "Detected in many" 19 "B-cells: 57.4" "Group enriched" "Detected in many" 4 "ASC diff: 24.4;hTERT-RPE1: 91.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" 21.3 10.7 18.0 6.4 26.5 0.1 20.1 26.2 15.4 39.5 8.6 21.2 4.4 23.9 17.8 18.3 25.2 21.9 46.0 16.1 30.1 6.1 1.4 8.9 7.0 26.5 29.1 33.8 8.0 3.2 3.8 4.6 27.9 22.4 12.7 2.9 9.4 34.4 60.7 4.4 7.7 24.3 31.5 8.7 7.7 8.3 21.5 8.7 17.1 79.0 12.1 19.2 15.4 38.4 0.8 1.6 4.0 0.0 24.4 14.5 0.2 6.9 10.8 1.1 3.1 0.1 9.5 0.0 1.8 11.0 6.0 3.0 0.0 0.5 2.1 0.1 0.0 0.0 0.1 0.0 2.9 0.1 0.0 9.3 1.0 3.5 0.8 91.6 0.4 0.0 0.0 0.1 8.4 1.9 0.6 1.9 7.9 0.6 2.7 0.3 10.7 3.2 2.4 8.3 0.4 6.3 2.7 0.6 7.0 4.0 0.9 0.3 3.0 2.5 1.8 3.4 1.8 0.3 1.2 0.2 5.3 0.0 8.6 0.0 0.0 2.7 0.0 0.0 0.5 57.4 0.0 0.0 0.1 16.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.7 18.0 26.5 26.2 15.4 16.1 30.1 26.5 29.1 27.9 31.5 21.5 38.4 10.8 3.2 3.2 39.2 30.7 13.6 23.1 21.6 30.1 2.1 21.8 89.2 95.4 10.0 14.8 18.4 0.0 74.0 1.4 36.0 5.9 11.4 4.0 12.4 52.1 10.2 4.9 1.3 3.5 7.1 7.5 140.8 3.6 6.0 0.0 10.7 9.7 0.2 15.3 6.7 5.8 10.1 0.0 0.6 11.1 5.8 185.8 6.6 19.6 18.7 18.6 41.2 0.0 41.7 18.4 2.8 7.3 267.4 41.2 19.4 0.6 3.1 7.9 2.7 39.5 139.9 56.3 0.7 3.8 7.7 7.1 27.8 2.1 30.7 7.7 24.7 STRIT1 DWORF ENSG00000240045 "Small transmembrane regulator of ion transport 1" P0DN84 3 155290227-155293683 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 79 "skeletal muscle: 1711.3;tongue: 698.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.1;prostate cancer: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Not detected" "Not detected" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (6.77e-4)" "unprognostic (1.60e-2)" "unprognostic (6.62e-2)" "unprognostic (1.58e-1)" "unprognostic (7.82e-3)" "unprognostic (1.33e-2)" 0.6 0.1 3.5 0.2 15.2 0.2 0.5 4.5 3.5 0.0 2.8 0.2 6.3 0.2 0.5 14.1 0.1 0.4 5.5 3.3 2.8 5.9 0.3 0.2 0.3 3.1 4.1 0.1 0.3 0.1 0.1 0.1 4.2 12.1 0.2 0.3 8.7 0.1 1711.3 2.2 3.6 0.0 1.7 0.2 0.2 0.2 7.5 0.0 0.4 698.4 0.1 0.0 0.1 5.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.3 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.4 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 15.2 4.5 3.5 3.3 2.8 3.1 4.1 4.2 1.7 7.5 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Yes No 750000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "CAB025743: , HPA024040: AB_1857651, HPA074892: " "unprognostic (2.93e-1)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.42e-2)" "prognostic favorable (3.96e-4)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.71e-4)" 64.1 64.6 26.1 43.0 29.7 51.5 57.5 29.3 27.1 91.3 45.0 67.4 89.2 57.5 64.8 46.8 102.6 70.6 30.8 25.1 27.8 93.4 94.8 71.6 50.2 35.2 29.6 59.7 91.8 115.8 31.8 45.5 33.4 79.3 69.1 11.0 69.5 77.1 22.4 47.5 74.4 57.7 29.9 57.0 92.7 23.7 30.8 57.6 91.2 21.4 51.3 57.2 43.6 35.9 352.3 102.9 46.0 211.8 214.4 147.5 68.9 114.5 156.1 92.6 114.5 57.2 278.0 57.1 96.5 162.4 90.4 172.3 27.4 131.3 61.1 90.6 42.9 36.4 63.5 54.2 138.4 89.7 108.7 116.8 124.5 83.7 143.3 186.9 137.7 101.4 116.4 236.6 151.3 76.8 77.2 115.7 63.5 272.0 52.2 61.5 45.4 359.0 127.7 39.1 54.0 65.6 142.4 294.2 140.9 98.9 294.5 144.5 115.2 85.6 121.1 211.1 98.6 160.8 130.8 84.0 139.7 165.7 283.2 58.1 60.3 22.0 71.1 80.5 90.9 59.8 70.9 71.8 72.3 49.1 75.3 75.2 4.4 49.0 90.3 132.6 82.7 90.2 26.1 29.7 29.3 27.1 25.1 27.8 35.2 29.6 33.4 29.9 30.8 35.9 44.0 57.7 30.5 20.5 47.3 33.8 44.1 46.1 39.9 25.7 57.9 25.4 10.4 87.2 31.0 90.1 14.6 44.5 85.3 45.1 19.6 95.3 3.8 93.1 70.2 43.7 59.3 41.7 21.2 55.7 96.7 54.7 55.5 78.9 54.5 47.0 51.0 91.3 68.1 43.7 24.4 61.8 22.4 79.8 38.7 8.0 69.6 50.4 53.4 14.0 73.0 23.8 70.0 10.6 24.2 48.4 64.6 47.4 65.0 50.7 91.8 45.6 34.5 13.5 52.6 41.6 44.1 31.6 28.6 52.8 41.9 46.7 52.7 58.7 85.8 42.7 SVEP1 "bA427L11.3, C9orf13, FLJ13529, POLYDOM" ENSG00000165124 "Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" Q4LDE5 9 110365248-110579880 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.6;placenta: 61.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 92.8;Inhibitory neurons: 50.3;Leydig cells: 42.0;Oligodendrocytes: 140.5;Syncytiotrophoblasts: 67.3;Theca cells: 34.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 147.1;ASC TERT1: 84.7;BJ hTERT+: 62.3;HHSteC: 53.8;HSkMC: 66.7" "Region enhanced" "Detected in some" "cerebellum: 2.8" "Region enriched" "Detected in all" 5 "cerebellum: 20.8" "HPA020610, HPA021520" Enhanced "Intracellular and membrane" NA NA 160000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA020610: AB_2197021, HPA021520: AB_1855533" "unprognostic (4.47e-2)" "unprognostic (6.01e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.62e-2)" "unprognostic (9.13e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (3.31e-3)" "unprognostic (2.25e-1)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (9.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.55e-3)" 38.6 4.2 1.5 2.5 8.6 0.0 23.2 8.9 2.8 10.6 0.9 9.7 1.2 8.6 5.6 3.5 12.4 6.2 6.5 1.1 3.4 3.9 2.9 19.7 3.8 2.7 5.3 3.9 4.7 5.3 0.8 61.7 3.3 1.7 5.1 0.0 4.1 2.1 4.4 11.3 8.7 9.5 1.0 5.2 7.7 1.0 4.3 1.8 7.4 5.5 2.4 9.7 12.1 6.1 0.0 0.1 1.2 0.0 147.1 84.7 0.0 16.3 62.3 1.2 1.9 1.5 0.0 0.0 0.0 3.9 0.1 0.0 0.0 12.2 1.0 0.0 0.3 0.1 1.4 0.0 53.8 0.0 2.9 66.7 0.0 12.1 3.2 1.4 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.2 7.5 2.0 0.0 10.6 0.0 0.0 0.0 2.3 0.0 1.0 0.0 1.3 2.5 0.0 7.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 8.6 8.9 2.8 1.1 3.4 2.7 5.3 3.3 1.0 4.3 6.1 7.4 0.0 0.5 2.9 0.1 5.7 0.6 0.5 1.2 0.5 0.4 0.9 1.8 5.7 0.1 0.0 0.0 12.2 0.3 0.0 0.0 0.9 0.3 0.5 13.8 2.0 0.0 0.0 16.9 0.2 1.6 92.8 4.1 0.3 0.0 0.0 2.2 0.0 3.0 0.0 50.3 0.0 0.0 0.0 8.2 0.6 42.0 0.6 7.2 13.1 0.0 0.0 0.0 3.0 140.5 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 3.5 7.8 0.4 1.5 0.4 3.3 67.3 1.2 34.1 0.2 0.2 TAFA5 "FAM19A5, TAFA-5" ENSG00000219438 "TAFA chemokine like family member 5" Q7Z5A7 22 48489553-48850912 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 85.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Fibroblasts: 1.1" "Cancer enhanced" "Detected in all" "glioma: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 17.3;HEK 293: 13.6;Hep G2: 32.1;NTERA-2: 12.7;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025629 Approved "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB025629: " "unprognostic (2.86e-1)" "unprognostic (2.98e-1)" "unprognostic (3.42e-2)" "unprognostic (2.19e-1)" "unprognostic (3.57e-1)" "unprognostic (1.80e-1)" "unprognostic (2.82e-3)" "unprognostic (2.41e-2)" "unprognostic (6.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.26e-1)" "unprognostic (9.31e-3)" "unprognostic (2.64e-2)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.94e-2)" 2.7 1.3 50.3 0.8 40.6 0.0 2.0 37.0 51.8 19.7 15.0 8.4 1.0 8.1 4.7 0.9 5.2 2.0 2.5 53.9 43.0 2.4 2.7 2.1 0.4 55.2 85.9 12.1 2.4 4.3 7.0 0.1 51.1 6.8 0.2 3.6 4.9 3.2 1.5 5.4 3.3 0.7 41.5 0.3 2.9 3.3 49.6 1.2 0.8 1.7 0.1 4.0 4.9 28.2 0.0 1.3 2.5 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 17.3 0.1 0.1 1.3 0.0 0.0 0.0 13.6 0.0 0.2 32.1 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.3 12.7 0.6 0.0 0.6 0.0 7.4 0.0 0.0 7.2 0.2 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 40.6 37.0 51.8 53.9 43.0 55.2 85.9 51.1 41.5 49.6 28.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX15 TBX14 ENSG00000092607 "T-box transcription factor 15" Q96SF7 1 118883046-118989556 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.8;skeletal muscle: 132.2;tongue: 114.7" "Cell type enhanced" "Detected in some" "Early spermatids: 8.2;Fibroblasts: 11.1;Hepatocytes: 15.3;Melanocytes: 7.2;Skeletal myocytes: 13.1;Smooth muscle cells: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 52.6;ASC TERT1: 22.1;BJ hTERT+ SV40 Large T+ RasG12V: 20.4;fHDF/TERT166: 28.2;HSkMC: 37.9;RH-30: 29.1;U-2197: 27.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.3" "HPA052245, HPA053713" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Centrosome "HPA052245: AB_2681771, HPA053713: " "unprognostic (1.94e-1)" "unprognostic (2.75e-3)" "unprognostic (1.92e-2)" "unprognostic (3.94e-2)" "unprognostic (5.72e-3)" "unprognostic (7.79e-2)" "unprognostic (5.82e-2)" "unprognostic (2.46e-1)" "unprognostic (3.00e-3)" "unprognostic (1.39e-1)" "unprognostic (3.81e-3)" "unprognostic (5.03e-2)" "prognostic unfavorable (5.57e-8)" "unprognostic (2.63e-2)" "unprognostic (3.90e-2)" "unprognostic (1.88e-3)" "unprognostic (2.31e-1)" 29.8 0.1 0.8 0.0 1.0 0.0 16.1 0.7 1.3 0.1 2.1 0.1 0.0 0.2 0.1 1.9 0.4 0.5 3.1 0.7 0.6 1.0 46.8 0.6 2.7 0.6 0.7 0.1 0.1 0.5 1.5 0.1 0.7 1.4 0.0 0.2 6.9 0.0 132.2 9.4 0.1 0.1 0.5 0.0 0.1 0.7 0.9 0.3 1.9 114.7 1.3 0.4 0.3 0.7 1.4 0.0 0.0 0.0 52.6 22.1 0.0 4.7 6.4 12.3 20.4 0.0 0.0 0.0 2.6 28.2 0.0 0.0 0.0 0.0 4.9 0.0 0.3 0.0 1.4 0.0 0.1 0.4 0.0 37.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 14.1 0.0 0.0 0.2 2.3 0.0 0.2 0.0 29.1 0.4 3.0 1.4 0.6 0.0 1.6 0.0 0.6 0.6 0.0 0.6 0.0 6.6 4.0 27.3 0.2 0.4 0.2 0.0 13.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.7 1.3 0.7 0.6 0.6 0.7 0.7 0.5 0.9 0.7 3.2 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.2 0.1 0.0 1.2 0.0 0.0 0.3 0.0 0.0 11.1 0.0 0.1 0.0 0.0 0.0 15.3 0.1 0.0 0.2 0.0 0.0 0.0 4.0 1.1 0.0 0.1 7.2 1.9 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.1 12.5 0.2 0.4 0.0 2.0 0.0 0.3 0.1 0.0 0.0 TCF7L1 TCF3 ENSG00000152284 "Transcription factor 7 like 1" Q9HCS4 2 85133392-85310387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Astrocytes: 76.4;Leydig cells: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 43.3;NTERA-2: 99.0;RH-30: 44.7;T-47d: 44.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071298 Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA071298: AB_2686383" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.05e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (6.16e-5)" "unprognostic (1.79e-2)" "unprognostic (3.59e-3)" "unprognostic (2.73e-1)" "unprognostic (5.17e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (2.06e-4)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (5.38e-4)" 37.8 5.3 7.5 4.0 9.9 3.7 33.4 7.8 6.4 33.1 13.8 27.6 4.3 25.9 6.7 10.0 20.1 7.2 20.3 6.9 7.7 15.7 12.5 17.8 5.9 10.8 13.0 27.5 4.5 7.0 8.9 5.2 6.9 20.0 4.1 1.7 13.1 14.5 15.0 14.6 12.2 13.0 7.4 11.8 10.7 9.1 10.0 5.8 30.6 7.9 3.5 18.3 24.1 6.7 2.1 1.5 33.5 25.8 12.6 2.6 20.3 2.5 8.5 5.8 5.3 5.2 2.0 0.7 4.0 5.6 6.4 4.7 25.9 43.3 4.0 1.8 4.1 0.7 2.1 2.3 1.2 0.3 4.9 2.1 7.7 0.6 1.4 2.6 11.2 1.3 0.5 1.3 6.8 1.6 0.2 1.6 99.0 1.3 0.9 0.6 44.7 0.5 2.7 3.7 1.0 10.4 4.0 17.1 1.3 25.9 44.3 0.9 12.1 6.5 9.2 0.4 3.3 1.1 0.3 0.4 0.2 1.0 5.2 5.1 0.5 1.1 0.5 0.4 0.7 1.1 0.6 0.7 0.2 1.5 0.7 0.9 1.3 0.9 0.5 0.9 0.6 0.1 7.5 9.9 7.8 6.4 6.9 7.7 10.8 13.0 6.9 7.4 10.0 6.7 49.2 6.4 37.3 76.4 1.0 6.0 14.4 12.9 15.9 0.2 20.0 33.1 9.1 5.7 10.5 16.5 0.0 6.3 0.8 0.3 0.0 3.7 28.2 9.4 17.5 31.4 0.0 0.0 1.1 5.6 4.0 28.9 0.5 16.0 5.1 39.4 45.7 6.7 1.7 0.0 2.2 2.9 8.2 9.1 8.3 5.4 65.3 2.2 3.6 22.5 1.0 4.9 0.0 32.2 1.5 1.1 1.6 28.6 1.4 10.8 5.0 2.2 7.7 0.2 6.6 24.9 28.9 1.9 9.3 3.4 3.4 1.4 1.2 2.9 2.1 2.4 TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.9;Hepatic stellate cells: 322.7;Leydig cells: 146.3;Skeletal myocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 35.2" "Group enriched" "Detected in many" 18 "NK-cells: 16.6;T-cells: 35.2" "Cell line enhanced" "Detected in many" "ASC diff: 227.2;ASC TERT1: 108.4;RT4: 57.1;U-2197: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" NA NA 50000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB018971: , HPA008257: AB_1080258" "unprognostic (7.57e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (9.39e-3)" "prognostic favorable (4.84e-4)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "prognostic favorable (4.99e-4)" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.08e-2)" 66.3 35.2 6.9 9.2 6.8 5.0 62.1 7.6 8.0 56.6 20.4 28.8 8.2 33.9 24.2 28.5 36.6 20.0 16.2 7.6 6.7 28.2 16.6 27.3 7.2 6.0 10.1 81.5 12.3 5.9 7.1 58.5 7.8 16.4 12.5 1.5 35.0 32.7 12.8 25.0 19.7 27.4 7.9 40.0 18.1 11.0 8.0 7.7 13.2 29.4 4.2 47.3 28.6 7.8 9.9 9.4 14.1 2.4 227.2 108.4 44.6 7.1 35.3 8.1 9.9 4.4 1.4 0.1 1.7 13.0 6.4 1.4 3.6 1.0 6.2 34.1 7.6 0.0 11.1 41.2 5.0 0.3 0.1 26.3 4.7 17.8 4.0 1.3 4.2 0.0 23.6 0.7 2.4 0.2 0.1 0.1 5.9 4.6 3.2 0.5 4.8 2.1 3.2 57.1 0.7 0.0 3.4 0.2 20.4 5.8 1.2 3.7 12.7 13.5 3.5 78.0 1.7 34.8 3.3 0.0 2.8 1.9 1.7 1.2 0.0 0.0 35.2 0.2 19.4 0.0 8.7 19.2 0.0 0.0 2.7 12.7 0.6 16.6 1.4 1.2 4.5 8.1 6.9 6.8 7.6 8.0 7.6 6.7 6.0 10.1 7.8 7.9 8.0 7.8 77.6 9.6 9.7 58.8 3.1 37.6 10.0 2.3 44.3 0.3 38.2 60.1 20.7 30.0 4.2 31.3 2.1 27.5 66.7 0.5 3.9 2.0 54.3 11.2 32.8 90.5 24.0 10.7 7.7 5.1 12.0 143.9 5.1 8.1 2.5 20.5 322.7 21.0 11.8 0.0 34.0 1.9 8.2 23.2 29.4 29.8 146.3 5.2 35.6 82.4 0.7 1.2 62.8 7.5 0.9 3.3 0.4 74.4 21.3 8.5 1.4 20.9 8.3 0.2 13.1 187.2 36.5 0.8 2.2 17.2 34.1 58.0 36.9 92.2 3.7 8.0 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 216.7;heart muscle: 167.9;smooth muscle: 251.4;tongue: 214.6" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 493.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.5" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.5" "Cell line enhanced" "Detected in some" "AF22: 3.1;THP-1: 7.0;U-2 OS: 2.8;U-266/70: 2.6" "Region enriched" "Detected in many" 8 "white matter: 85.7" "Region enriched" "Detected in many" 27 "spinal cord: 89.3" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 510000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB004597: AB_628352, HPA042426: AB_2677992" "unprognostic (1.41e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.64e-2)" "unprognostic (9.94e-2)" "unprognostic (8.10e-2)" "unprognostic (5.64e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-3)" "unprognostic (2.74e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.33e-4)" 216.7 1.2 15.4 5.2 19.6 10.6 26.8 13.8 13.0 2.1 5.0 58.1 2.2 26.8 1.6 6.0 2.5 10.4 167.9 12.2 24.5 0.7 0.3 1.3 1.1 22.3 25.3 4.1 22.8 35.7 14.3 0.2 19.9 9.0 8.7 7.5 46.5 5.7 77.2 2.9 3.3 251.4 21.7 0.3 8.6 8.7 28.0 3.6 27.0 214.6 4.0 3.5 5.8 20.0 0.1 0.0 3.1 0.2 0.2 1.3 0.3 0.1 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.2 0.8 0.1 0.1 0.4 0.8 0.1 0.4 0.3 0.0 0.2 1.7 0.0 0.0 0.9 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 2.4 0.0 0.0 0.0 0.9 0.0 0.2 0.0 2.5 0.7 0.0 0.0 0.2 1.3 0.0 7.0 0.0 0.0 2.8 0.2 0.2 2.6 0.1 0.4 1.1 2.2 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 19.6 13.8 13.0 12.2 24.5 22.3 25.3 19.9 21.7 28.0 20.0 57.0 0.0 1.1 37.2 0.7 0.3 0.1 0.2 2.2 1.3 0.8 1.8 9.1 0.0 0.7 3.7 56.3 0.1 0.5 0.0 0.0 0.2 40.8 0.3 0.8 9.4 9.0 0.0 9.7 0.0 0.0 84.2 0.5 0.3 0.0 5.9 0.4 0.2 0.1 1.7 12.7 0.0 0.0 0.0 0.3 7.2 0.9 2.7 1.8 6.5 0.0 2.2 0.0 60.3 24.0 0.0 0.0 43.6 0.3 1.0 0.0 0.8 0.2 1.9 493.0 78.9 116.9 14.5 2.1 0.6 1.0 0.0 2.1 1.2 0.0 0.0 THRA "AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3" ENSG00000126351 "Thyroid hormone receptor alpha" P10827 17 40058290-40093867 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 236.7" "Cell type enhanced" "Detected in many" "Muller glia cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009654, CAB023349" Approved Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB023349: AB_619577, HPA009654: AB_1854603" "unprognostic (2.75e-2)" "unprognostic (2.20e-1)" "unprognostic (6.64e-2)" "unprognostic (4.22e-2)" "unprognostic (8.78e-2)" "unprognostic (1.64e-1)" "unprognostic (3.41e-3)" "prognostic favorable (1.84e-4)" "unprognostic (1.47e-1)" "unprognostic (5.47e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-2)" "prognostic favorable (6.05e-8)" "unprognostic (3.05e-1)" "unprognostic (1.35e-1)" "unprognostic (4.21e-1)" "unprognostic (1.88e-3)" 40.7 43.7 199.1 12.0 236.7 23.0 38.9 159.3 218.3 67.5 108.5 67.2 31.1 49.9 22.0 19.1 57.7 25.8 63.8 189.7 181.8 34.1 10.2 32.2 9.7 162.4 172.1 90.7 31.3 29.9 50.0 17.1 149.4 34.5 18.8 35.4 27.3 35.5 90.7 50.2 36.2 34.6 166.5 13.9 48.0 18.7 183.6 12.8 32.6 52.8 6.3 45.0 45.9 179.9 4.9 37.6 11.5 28.9 77.4 28.2 4.2 19.3 23.0 19.6 18.2 31.5 27.2 5.6 31.3 37.6 8.7 11.4 22.6 11.7 10.6 2.1 21.6 10.4 44.5 13.4 26.0 16.9 11.2 45.1 9.5 18.4 7.1 45.4 26.6 16.7 21.2 5.2 16.5 7.1 22.8 27.4 10.6 24.6 11.8 32.1 22.7 27.6 6.4 3.3 19.5 17.7 14.8 23.3 33.7 17.5 27.3 19.5 18.7 19.4 18.9 17.7 5.9 11.9 9.0 3.4 12.0 19.1 10.6 0.2 0.3 1.9 2.0 0.1 0.8 0.2 0.8 1.2 0.3 0.4 1.4 1.7 1.1 2.1 0.3 0.6 1.0 0.7 199.1 236.7 159.3 218.3 189.7 181.8 162.4 172.1 149.4 166.5 183.6 179.9 32.2 19.2 7.3 27.1 6.2 10.6 28.1 3.3 31.3 76.4 19.6 21.2 45.4 38.6 2.7 33.1 20.9 0.8 16.5 37.9 50.9 12.3 1.1 20.5 29.5 20.8 25.1 17.9 19.1 14.8 1.4 36.8 29.0 12.1 14.0 23.1 24.7 13.8 11.6 62.2 24.2 22.6 6.1 10.6 5.1 2.7 51.6 8.6 19.6 8.4 5.1 95.2 37.0 15.6 26.5 6.9 14.6 49.7 3.9 17.2 58.8 29.9 7.5 22.5 19.7 84.7 44.4 0.3 27.3 14.6 10.4 0.3 18.1 16.3 39.9 13.8 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TIPARP "ARTD14, DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 302.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 53.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.5" "Cell line enhanced" "Detected in all" "HBEC3-KT: 168.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Microtubules "HPA036796: AB_10672268" "prognostic favorable (2.00e-5)" "unprognostic (3.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (9.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (4.27e-3)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (4.90e-3)" 67.5 56.6 16.5 16.0 19.3 74.1 39.7 17.7 22.3 29.8 15.2 15.1 13.5 30.6 14.7 55.1 39.5 27.9 34.6 16.4 21.2 28.2 44.3 27.4 13.7 33.4 27.9 40.2 29.6 99.2 15.1 12.5 22.9 25.9 14.4 18.3 10.3 27.8 17.6 39.5 23.1 43.7 19.9 10.9 21.9 50.3 25.7 21.7 17.0 9.6 18.1 65.0 24.0 21.9 42.8 29.6 9.8 8.4 35.7 25.9 8.0 70.0 56.4 34.9 48.2 17.2 86.9 12.7 22.2 79.9 46.5 42.1 25.1 168.0 51.4 27.3 18.5 21.0 29.0 11.7 15.2 7.4 38.1 21.3 103.0 35.6 84.9 93.8 32.3 9.4 16.9 49.9 122.5 8.2 6.4 9.8 11.2 53.5 24.5 10.5 22.5 43.6 36.7 20.1 29.5 7.5 55.2 16.9 11.9 22.5 26.2 12.5 70.2 15.1 4.9 28.5 25.1 53.9 10.6 11.3 25.7 11.3 51.4 53.5 5.0 7.5 6.1 3.3 8.6 2.9 5.9 8.2 3.6 5.4 3.6 4.9 15.9 11.6 9.2 5.0 7.4 3.3 16.5 19.3 17.7 22.3 16.4 21.2 33.4 27.9 22.9 19.9 25.7 21.9 112.8 86.6 98.3 27.7 43.9 196.0 117.3 51.7 185.5 5.0 62.0 57.7 29.9 31.5 66.5 7.3 39.6 5.1 97.0 38.3 21.5 35.2 302.3 114.6 118.7 45.6 54.5 7.0 3.6 23.5 10.3 109.0 57.6 169.4 115.0 12.2 20.3 18.9 19.2 21.9 8.7 32.4 18.3 18.5 97.5 28.0 19.6 101.7 37.4 12.2 17.3 10.1 16.5 22.1 20.4 36.9 40.1 19.2 60.5 83.9 40.4 16.2 43.5 10.4 13.1 138.0 87.7 58.0 33.4 100.1 121.5 7.5 105.4 7.3 18.2 187.8 TK2 SCA31 ENSG00000166548 "Thymidine kinase 2" O00142 16 66508003-66552544 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041162: AB_10961178" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.27e-3)" "unprognostic (3.94e-1)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (4.83e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-1)" "unprognostic (3.59e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.18e-6)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (7.05e-2)" 48.1 30.2 24.2 11.8 27.6 8.5 25.6 24.7 25.7 20.0 19.7 15.0 10.9 16.2 29.3 12.3 19.0 21.1 19.2 24.1 25.6 25.1 37.3 18.7 11.7 26.5 27.8 26.8 24.4 38.0 22.4 15.1 27.6 19.2 12.7 11.7 22.6 19.9 11.5 12.7 13.5 18.9 27.5 23.0 15.7 33.9 25.8 13.0 25.6 14.6 9.9 17.8 15.4 28.3 13.3 26.5 12.1 14.5 64.3 52.2 0.7 22.0 22.3 15.1 16.8 6.5 26.4 0.1 23.8 63.9 19.0 11.8 5.3 17.7 10.4 8.5 6.2 4.1 17.2 12.9 45.1 5.6 9.2 39.4 15.3 18.5 26.1 62.5 19.9 13.1 6.8 28.1 37.9 4.1 5.5 14.9 5.9 5.1 15.4 7.0 21.0 28.1 44.1 12.5 4.4 8.9 63.2 6.1 26.9 6.6 9.6 16.3 29.7 30.8 15.9 26.3 7.6 30.3 12.2 11.6 38.9 5.7 18.4 5.6 9.4 6.0 1.8 5.1 1.2 0.1 1.3 1.0 8.7 1.7 0.6 0.9 8.5 2.7 4.3 1.8 1.2 2.5 24.2 27.6 24.7 25.7 24.1 25.6 26.5 27.8 27.6 27.5 25.8 28.3 25.0 22.4 9.3 19.6 7.3 5.7 5.1 5.8 12.5 15.5 15.4 11.4 8.0 17.2 7.5 22.0 22.9 10.0 7.6 6.0 9.8 15.7 25.2 15.2 23.2 14.4 9.6 10.3 10.1 22.4 6.0 19.9 11.7 13.0 24.8 20.6 31.1 48.9 21.7 21.9 12.0 6.5 2.0 55.6 10.1 40.5 23.3 23.6 10.6 10.3 22.6 18.4 12.3 14.6 19.4 28.9 3.3 19.2 12.4 4.3 14.4 45.9 9.0 20.5 0.0 14.4 10.6 48.9 11.1 9.6 3.8 2.9 8.6 22.2 7.6 4.2 TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 112.4;Proximal enterocytes: 68.9;Skeletal myocytes: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 3.4;neutrophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.0;HaCaT: 8.4;SiHa: 11.2;T-47d: 9.4" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 14.2" HPA046063 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" 10.3 9.4 0.6 1.8 0.7 2.1 4.7 1.6 0.9 3.0 2.3 7.3 6.0 1.8 1.2 4.7 2.7 1.8 2.1 0.6 0.5 1.8 7.0 3.9 0.7 1.0 0.7 2.5 1.2 1.0 1.1 1.5 1.0 1.9 5.3 10.5 2.9 0.9 1.7 2.4 6.9 1.2 0.7 1.3 4.7 0.6 1.0 0.1 1.6 0.8 0.8 3.1 3.5 1.6 1.0 1.1 1.1 3.5 8.1 9.0 0.3 1.9 1.8 1.0 0.7 6.9 3.1 0.1 1.9 3.1 1.0 8.4 1.5 0.9 0.7 0.2 0.7 0.9 2.4 0.3 2.3 0.1 2.4 7.6 3.2 1.2 2.2 2.9 0.7 0.1 0.8 0.4 0.9 1.9 0.1 0.4 0.1 3.4 0.6 0.1 5.3 0.2 0.7 2.7 0.2 0.4 11.2 1.0 1.6 1.5 9.4 0.8 2.6 0.5 2.3 2.1 0.5 0.1 0.1 0.1 0.6 0.3 1.0 3.4 0.2 0.4 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.4 0.2 0.2 1.6 0.3 0.1 0.2 0.1 0.1 0.6 0.7 1.6 0.9 0.6 0.5 1.0 0.7 1.0 0.7 1.0 1.6 19.0 51.3 55.5 0.3 1.6 0.0 8.2 0.0 4.0 7.9 5.8 9.5 2.7 17.2 18.0 11.0 129.3 4.9 2.0 112.4 0.0 7.3 1.1 12.9 10.4 14.1 9.0 11.2 0.5 9.6 2.6 14.9 20.9 13.3 15.8 3.9 18.9 24.2 5.5 0.0 0.4 24.6 0.0 6.5 0.0 1.8 13.4 10.7 0.0 3.7 1.4 11.7 0.0 0.0 0.1 13.5 40.1 5.7 3.3 6.3 68.9 1.1 19.9 57.8 6.6 124.2 17.8 0.6 0.8 9.1 0.3 4.0 5.1 5.4 35.7 13.0 TMDD1 "C12orf81, hCG1648055" ENSG00000284730 "Transmembrane and death domain 1" P0DPE3 12 51813940-51814926 "Predicted membrane proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Fibroblasts: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Fibroblasts - ECM organization" 0.6 0.0 0.4 0.0 0.3 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.4 0.3 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.5 0.4 0.6 0.2 0.2 0.1 0.2 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM114 ENSG00000232258 "Transmembrane protein 114" B3SHH9 16 8537605-8590193 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "seminal vesicle: 19.6" "Cell type enhanced" "Detected in single" "Microglial cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hypothalamus: 6.6" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.72e-5)" "unprognostic (2.26e-1)" "unprognostic (3.98e-3)" "unprognostic (7.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.62e-1)" "unprognostic (2.21e-1)" 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 0.6 0.0 2.9 0.1 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 3.1 1.1 1.7 2.9 0.3 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM255A "FAM70A, FLJ20716" ENSG00000125355 "Transmembrane protein 255A" Q5JRV8 X 120258650-120311556 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.7;ovary: 19.6" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 32.6;Skeletal myocytes: 14.6" "Group enriched" "Detected in many" 10 "glioma: 21.3;melanoma: 8.0;renal cancer: 7.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.8" "Lineage enriched" "Detected in single" 9 "T-cells: 2.8" "Cell line enhanced" "Detected in some" "Karpas-707: 25.3;NTERA-2: 9.5;RPMI-8226: 17.1;SK-MEL-30: 27.7;U-2 OS: 11.8;U-87 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048470 Approved Uncertain "Nucleoplasm,Nuclear bodies" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "HPA048470: AB_2680406" "unprognostic (3.41e-2)" "unprognostic (8.96e-2)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" "unprognostic (8.55e-4)" "unprognostic (7.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.36e-1)" "unprognostic (1.49e-3)" "unprognostic (2.02e-1)" "unprognostic (1.32e-2)" "unprognostic (3.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.17e-2)" "unprognostic (2.55e-4)" 4.7 3.3 7.4 1.8 5.8 0.7 3.2 4.8 9.2 11.9 1.7 2.6 0.7 1.9 1.6 2.8 3.8 1.1 1.3 3.8 27.4 1.4 0.6 3.0 3.6 22.7 48.7 19.6 0.4 1.4 3.8 0.2 33.0 1.4 2.3 1.5 1.2 1.8 1.4 2.6 2.3 0.9 19.9 1.7 1.8 0.2 36.8 8.1 0.4 2.7 3.8 1.9 8.5 11.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.5 0.2 0.0 0.1 0.3 0.0 2.9 0.0 1.9 0.7 0.7 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 25.3 0.4 0.0 0.0 0.1 9.5 0.0 0.0 0.1 0.0 17.1 0.0 0.0 5.1 0.1 0.5 0.0 27.7 0.3 0.0 0.3 0.0 0.0 11.8 0.0 5.1 0.0 5.2 3.7 29.7 0.0 0.0 0.0 0.3 0.0 2.8 0.1 1.4 0.2 0.2 1.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 7.4 5.8 4.8 9.2 3.8 27.4 22.7 48.7 33.0 19.9 36.8 11.5 0.1 3.2 0.0 1.6 0.0 0.4 0.1 0.1 0.6 1.9 0.2 1.3 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.2 0.0 0.0 4.4 0.0 0.4 0.0 0.3 0.4 0.0 1.3 0.0 4.3 0.0 0.0 1.0 0.7 1.6 0.6 1.6 5.4 1.9 3.7 0.3 0.0 32.6 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 14.6 0.6 0.1 0.1 0.0 1.3 0.1 0.4 0.0 0.0 0.0 TMEM43 "ARVD5, DKFZp586G1919, LUMA, MGC3222" ENSG00000170876 "Transmembrane protein 43" Q9BTV4 3 14125015-14143680 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019198 Approved NA NA 34000 "Cluster 5: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA019198: AB_1858118" "unprognostic (3.65e-3)" "unprognostic (2.52e-1)" "unprognostic (4.03e-2)" "unprognostic (4.66e-1)" "unprognostic (5.45e-3)" "unprognostic (1.72e-1)" "unprognostic (1.28e-3)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.77e-2)" "unprognostic (5.45e-2)" "unprognostic (1.35e-3)" "unprognostic (2.19e-1)" "unprognostic (9.78e-2)" "unprognostic (1.18e-1)" 75.4 34.3 23.1 36.8 23.8 21.0 61.3 23.0 25.3 66.8 23.5 56.7 23.5 89.1 31.0 69.5 63.9 47.1 64.7 23.2 25.0 27.7 19.6 58.1 30.2 27.5 25.1 82.6 27.3 25.6 30.6 57.6 25.9 43.3 29.4 15.9 37.9 65.2 60.8 108.7 40.0 82.5 23.6 31.2 34.8 15.2 25.5 26.0 47.0 45.8 33.7 56.1 66.4 25.2 41.5 45.7 44.1 58.3 173.4 180.6 104.6 80.1 164.8 129.9 93.0 37.5 54.1 19.5 55.7 201.3 64.3 88.3 47.1 70.9 92.9 48.7 38.0 35.3 45.6 53.8 109.3 51.4 40.4 136.0 173.6 107.9 133.0 103.6 94.8 36.2 56.1 47.8 76.6 54.3 23.4 43.2 48.4 62.8 75.3 32.2 46.8 78.2 59.4 70.4 12.9 35.5 101.0 59.3 66.5 37.3 37.5 74.3 86.4 118.7 63.7 120.6 76.0 32.1 54.3 25.1 89.3 68.4 108.7 81.3 51.5 100.3 68.7 45.5 64.0 36.8 66.8 62.7 67.4 31.6 44.5 49.0 157.2 79.9 49.2 42.6 65.7 69.7 23.1 23.8 23.0 25.3 23.2 25.0 27.5 25.1 25.9 23.6 25.5 25.2 44.2 137.8 46.8 17.9 16.8 43.7 32.2 31.0 39.9 6.2 19.9 29.7 13.4 15.7 52.9 18.4 14.6 31.2 43.2 9.3 0.0 34.9 0.6 17.3 58.1 37.4 4.9 22.5 24.1 10.0 65.6 68.0 20.9 34.4 28.4 16.1 23.6 8.9 17.8 6.7 20.6 8.3 8.2 16.1 33.5 3.9 43.2 19.8 30.2 15.9 26.8 8.4 16.5 30.2 23.9 22.4 9.7 70.7 15.6 35.8 8.8 9.0 16.2 8.6 32.9 43.6 39.3 5.6 12.0 44.1 45.5 37.5 32.1 17.6 11.5 30.2 TMEM64 DKFZp762C1112 ENSG00000180694 "Transmembrane protein 64" Q6YI46 8 90621995-90791632 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "choroid plexus: 42.5;epididymis: 144.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 62.0;Hepatocytes: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034221 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB034221: AB_1567653" "unprognostic (3.61e-1)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (2.55e-3)" "unprognostic (4.84e-1)" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (3.30e-1)" "unprognostic (2.35e-1)" "unprognostic (2.59e-2)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.17e-2)" "unprognostic (1.97e-1)" 17.1 12.0 5.2 9.3 9.3 3.4 8.4 7.1 7.1 15.4 42.5 10.5 9.6 10.9 144.9 10.5 8.8 10.4 7.2 4.9 6.8 13.6 20.8 9.5 12.9 9.4 7.4 16.3 15.3 6.8 4.7 10.3 7.8 11.4 5.5 1.0 17.8 17.3 8.9 6.4 9.8 16.3 7.5 8.9 7.1 12.2 7.4 5.1 22.9 7.1 12.1 10.6 7.8 14.5 26.5 20.3 10.0 5.4 45.7 33.0 5.5 19.2 18.2 14.8 16.3 5.7 17.8 17.2 7.5 11.8 6.4 9.0 26.9 13.0 19.5 34.8 9.8 32.1 7.3 12.8 16.1 1.9 5.1 43.4 14.0 6.1 13.8 17.1 15.1 4.1 14.8 36.9 25.1 35.3 0.1 4.6 1.5 13.6 10.6 3.8 22.1 8.7 29.2 50.6 7.1 20.0 12.6 10.9 23.5 13.3 10.9 1.5 15.1 14.9 13.1 10.8 15.8 24.3 0.4 18.8 13.4 3.9 20.0 2.7 0.1 0.1 1.5 0.3 1.9 3.1 1.6 1.7 0.3 2.0 0.7 1.1 0.0 3.2 0.4 0.2 0.8 0.9 5.2 9.3 7.1 7.1 4.9 6.8 9.4 7.4 7.8 7.5 7.4 14.5 16.7 9.6 12.5 5.2 15.7 24.1 12.7 5.4 62.0 0.7 7.3 11.4 20.4 7.2 3.7 22.0 0.0 25.3 18.6 2.5 1.9 3.9 3.7 3.3 9.6 9.0 7.8 18.7 9.9 10.2 6.2 18.1 6.1 4.6 14.0 13.5 6.1 51.7 4.0 1.7 14.1 4.5 8.2 9.7 11.6 3.2 46.9 11.1 24.9 9.4 1.9 4.0 4.1 8.0 46.8 8.8 2.4 21.4 12.6 19.7 16.7 30.6 3.7 0.0 0.0 10.5 11.9 3.4 2.2 17.4 23.4 15.7 13.3 23.7 7.2 8.6 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" NA NA 36000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.7 16.2 11.7 24.1 13.0 14.1 19.2 14.2 15.4 15.0 9.9 12.7 18.2 16.6 20.4 14.1 13.8 16.5 20.8 13.5 13.2 14.6 16.2 19.5 27.9 11.1 11.2 13.0 11.9 15.9 9.6 19.8 12.1 17.7 16.3 26.0 10.6 13.0 11.0 16.7 18.8 21.0 11.4 22.6 14.0 11.4 12.1 23.3 17.7 21.0 22.7 20.1 11.2 11.5 11.1 17.4 32.9 25.9 66.6 70.7 24.5 85.7 91.0 61.0 67.7 8.4 31.9 31.4 16.6 125.4 25.9 40.8 21.9 42.9 92.8 30.3 19.6 28.8 27.4 14.7 70.6 62.0 45.7 56.5 27.1 66.2 59.2 61.8 78.4 27.0 18.9 42.5 73.1 6.9 33.3 19.6 13.9 9.1 28.2 30.7 65.5 38.5 51.7 24.2 31.5 24.5 42.0 26.7 31.8 32.4 17.6 52.1 76.4 108.4 30.0 24.7 63.6 28.4 30.4 29.4 65.5 50.1 81.3 2.2 2.9 2.4 3.8 4.7 5.5 3.1 3.9 3.6 4.7 2.1 4.3 4.4 0.7 4.9 3.3 6.4 4.4 2.7 11.7 13.0 14.2 15.4 13.5 13.2 11.1 11.2 12.1 11.4 12.1 11.5 31.4 28.9 27.8 36.2 25.0 20.3 17.2 17.6 12.0 29.1 21.0 15.6 25.1 10.0 18.8 16.5 18.8 15.0 44.3 10.6 1.9 15.2 8.9 18.7 38.5 27.3 18.0 17.0 77.9 10.2 20.8 34.5 13.3 25.6 20.3 24.2 34.2 26.6 18.6 26.9 45.6 13.8 14.2 23.3 26.8 3.3 24.2 23.9 24.9 32.8 18.2 20.5 20.6 49.8 53.1 15.4 15.4 16.6 29.8 19.4 17.5 8.0 28.8 32.5 39.5 23.6 32.0 23.8 28.3 21.7 24.3 12.4 23.3 22.9 9.4 16.6 TNFAIP6 "TSG-6, TSG6" ENSG00000123610 "TNF alpha induced protein 6" P98066 2 151357592-151380046 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "urinary bladder: 196.0" "Cell type enhanced" "Detected in many" "Early spermatids: 443.9;Fibroblasts: 302.3;Langerhans cells: 137.4;Melanocytes: 74.7" "Cancer enhanced" "Detected in many" "renal cancer: 27.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "neutrophil: 183.0" "Lineage enriched" "Detected in many" 22 "granulocytes: 183.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 67.5;HHSteC: 40.3;hTEC/SVTERT24-B: 54.9;SH-SY5Y: 21.6;U-2197: 44.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB032719, HPA050884" Uncertain "Secreted to blood" NA NA 100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB032719: AB_2204650, HPA050884: AB_2681261" "unprognostic (1.31e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (8.66e-2)" "unprognostic (2.51e-2)" "unprognostic (1.15e-3)" "unprognostic (3.26e-3)" "unprognostic (3.75e-4)" "unprognostic (4.49e-3)" "unprognostic (1.22e-1)" "unprognostic (1.90e-1)" "unprognostic (5.87e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.59e-4)" "unprognostic (1.06e-2)" "unprognostic (1.25e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (9.16e-5)" 15.6 0.5 1.9 27.6 2.2 7.6 11.1 1.5 2.8 9.2 1.2 6.3 0.7 2.0 0.3 2.2 2.2 19.8 15.4 1.7 2.2 0.4 1.2 11.0 0.6 1.6 2.2 0.5 1.2 0.3 0.4 1.8 1.9 3.2 2.8 0.0 3.4 0.9 1.7 2.7 2.2 7.2 1.6 3.0 4.0 10.6 2.6 1.4 1.6 2.8 0.5 196.0 1.6 2.3 0.0 0.0 0.0 0.0 3.8 15.5 0.0 2.5 67.5 2.5 12.4 0.0 0.0 0.0 0.8 1.1 1.4 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.3 0.0 40.3 0.0 0.0 19.5 0.0 54.9 3.8 2.3 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.3 0.0 15.5 0.0 1.1 0.0 0.0 0.0 0.0 21.6 0.5 0.0 0.0 0.4 0.0 0.0 0.0 2.2 4.4 44.3 0.8 0.0 0.0 0.0 4.8 0.7 3.3 0.0 8.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 183.0 0.0 2.1 0.0 0.0 2.5 1.9 2.2 1.5 2.8 1.7 2.2 1.6 2.2 1.9 1.6 2.6 2.3 4.5 3.2 1.7 1.3 1.1 64.7 0.9 11.1 0.0 0.0 1.5 1.4 2.2 0.0 1.5 0.0 0.0 0.1 0.3 0.1 0.0 2.8 443.9 2.9 2.7 7.3 0.0 0.8 0.7 0.0 0.9 302.3 0.5 10.6 2.5 0.0 1.4 0.0 1.4 0.0 0.4 0.0 0.0 6.9 137.4 38.5 2.5 49.6 74.7 1.9 5.9 0.0 0.0 13.6 7.1 1.5 0.0 0.4 1.4 3.0 0.0 0.2 0.2 0.0 0.0 40.6 45.5 10.7 1.9 1.0 53.0 1.8 6.0 0.3 0.0 3.8 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TRIL KIAA0644 ENSG00000255690 "TLR4 interactor with leucine rich repeats" Q7L0X0 7 28953358-28958330 "Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 68.0" "Cell type enriched" "Detected in many" 4 "Astrocytes: 72.1" "Cancer enhanced" "Detected in many" "glioma: 20.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 22.2;SH-SY5Y: 40.0;SK-BR-3: 35.7;T-47d: 15.8" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.26e-3)" "unprognostic (3.29e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (4.27e-3)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (2.07e-2)" 4.7 2.3 40.8 0.6 61.3 0.0 4.1 57.4 35.0 2.9 7.3 2.0 2.0 3.6 1.7 2.4 2.3 1.0 4.3 32.5 40.8 5.9 0.6 2.6 0.4 58.2 65.2 1.6 0.5 0.8 1.6 1.1 46.1 1.9 1.8 1.0 8.2 1.4 3.1 1.9 2.4 3.4 49.7 2.6 2.3 0.5 68.0 0.4 2.9 0.7 0.3 2.3 3.5 35.9 0.0 0.0 22.2 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 6.1 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.8 40.0 0.1 35.7 0.0 3.2 15.8 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.8 61.3 57.4 35.0 32.5 40.8 58.2 65.2 46.1 49.7 68.0 35.9 7.0 12.8 5.3 72.1 0.0 0.0 0.2 0.0 4.0 0.4 7.4 11.0 2.7 0.0 0.6 1.8 0.0 0.2 0.0 0.1 3.9 0.1 0.0 0.4 0.2 4.3 0.0 0.0 0.7 0.0 1.9 15.9 0.0 1.1 0.0 0.2 2.5 0.4 0.1 6.7 0.6 0.4 0.0 0.0 0.0 0.2 1.2 0.5 0.0 5.6 0.0 17.1 0.0 13.0 0.4 0.0 0.2 0.0 0.0 0.0 0.1 1.8 0.0 0.8 13.1 15.2 4.9 0.5 0.7 2.2 0.0 0.1 0.1 2.0 0.8 0.1 TRIM65 ENSG00000141569 "Tripartite motif containing 65" Q6PJ69 17 75880335-75896951 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021575, HPA021578, HPA064820" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Cytosol" "HPA021575: AB_1858314, HPA021578: AB_1858315, HPA064820: AB_2685359" "unprognostic (1.82e-1)" "unprognostic (1.47e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-1)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "prognostic unfavorable (4.74e-6)" "unprognostic (5.36e-2)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (5.82e-2)" "unprognostic (6.00e-3)" "prognostic unfavorable (1.82e-5)" "unprognostic (2.86e-3)" "unprognostic (7.18e-2)" "unprognostic (4.24e-3)" "unprognostic (7.50e-3)" 13.0 7.8 12.5 8.5 15.2 7.4 10.7 15.3 13.5 15.5 11.0 14.1 8.8 14.7 6.8 14.2 13.1 7.1 10.3 11.5 13.2 11.2 8.4 12.9 10.5 15.0 14.6 14.1 15.7 7.4 11.8 5.4 14.8 11.7 7.9 7.2 12.6 8.1 13.2 14.6 13.5 8.3 13.8 16.6 11.3 3.9 14.5 6.5 12.2 6.9 8.2 14.6 14.0 17.0 19.8 20.2 7.8 22.2 13.5 19.2 4.0 8.3 8.9 11.1 9.4 9.1 17.0 21.4 6.5 7.2 15.6 13.7 16.8 18.6 6.8 11.1 28.9 16.9 20.4 12.5 13.4 17.2 18.9 12.0 14.4 8.9 16.0 9.3 29.2 27.2 29.3 19.5 8.7 20.6 38.0 33.7 17.7 20.0 19.5 31.3 11.2 30.9 11.2 8.2 16.1 14.9 11.4 21.3 22.7 9.7 21.2 24.2 14.5 26.6 13.5 13.3 16.9 17.9 7.4 6.2 16.2 32.2 11.8 1.4 1.1 1.8 1.9 1.0 2.2 1.4 1.4 1.9 0.9 2.0 1.5 1.5 1.1 1.9 0.6 1.3 1.3 0.6 12.5 15.2 15.3 13.5 11.5 13.2 15.0 14.6 14.8 13.8 14.5 17.0 8.4 6.4 4.8 13.1 7.5 2.9 5.7 2.4 3.4 19.0 3.7 3.0 4.3 5.7 3.4 9.2 12.5 0.9 9.0 3.6 1.9 3.2 0.4 2.8 9.2 8.2 0.0 9.5 4.5 3.4 3.6 6.6 7.1 4.0 7.0 8.6 5.7 3.8 8.9 5.0 5.9 6.6 6.1 5.4 9.3 0.5 13.7 6.9 8.8 3.7 4.9 6.3 3.1 6.6 9.3 5.3 2.9 9.4 5.8 5.1 4.8 5.9 1.8 12.9 0.0 9.3 5.2 0.8 2.9 6.7 3.7 0.5 8.5 6.4 5.9 2.8 TUG1 "FLJ20618, LINC00080, NCRNA00080" ENSG00000253352 "Taurine up-regulated 1" 22 30969245-30979395 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.83e-1)" "unprognostic (7.04e-2)" "unprognostic (1.87e-1)" "unprognostic (9.18e-2)" "unprognostic (8.34e-3)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.68e-1)" "unprognostic (2.89e-2)" "unprognostic (9.60e-3)" "unprognostic (3.98e-2)" "unprognostic (7.55e-2)" "unprognostic (1.50e-3)" "unprognostic (2.49e-1)" "unprognostic (1.93e-1)" "unprognostic (6.53e-2)" "prognostic favorable (8.27e-4)" 6.9 6.5 7.0 8.0 7.2 5.2 8.1 7.1 7.1 10.9 8.2 7.8 8.1 12.4 8.1 6.4 8.3 7.8 5.7 6.6 6.9 8.0 5.2 7.4 7.2 8.5 7.4 11.4 5.6 11.1 12.9 7.2 11.9 7.9 11.8 8.3 9.5 3.2 7.3 8.2 9.3 7.1 9.8 8.2 9.5 7.4 11.8 10.9 4.1 7.1 6.5 8.3 18.9 6.9 22.5 17.3 12.1 15.5 14.1 21.8 10.9 14.2 16.2 12.6 9.2 23.5 14.4 16.6 15.4 17.7 17.7 9.2 18.9 18.2 12.1 17.5 15.4 8.9 10.3 18.4 8.8 15.5 15.4 13.0 13.1 15.1 14.4 13.7 18.9 12.6 13.3 13.0 10.2 13.7 7.8 15.2 11.0 21.9 14.7 9.1 9.3 21.1 28.6 27.1 17.1 9.6 14.4 18.0 19.7 12.2 22.1 18.6 18.5 11.4 11.4 15.8 21.2 12.2 8.3 11.8 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 7.2 7.1 7.1 6.6 6.9 8.5 7.4 7.2 7.1 7.4 8.3 0.0 0.0 0.0 91.7 16.8 34.2 36.2 30.2 35.9 56.6 0.0 0.0 0.0 40.0 19.2 0.0 56.3 38.7 6.7 44.2 0.0 0.0 57.8 0.0 0.0 26.3 64.8 25.4 32.8 0.0 26.1 21.7 34.7 0.0 8.9 0.0 60.0 23.3 23.1 53.8 41.2 59.1 24.4 36.8 22.4 44.7 56.8 25.8 16.0 60.0 29.4 46.6 21.6 38.7 67.5 0.0 29.3 62.4 16.8 45.2 33.1 0.0 21.9 52.1 26.3 55.2 16.3 42.6 18.0 51.2 44.0 36.9 12.7 0.0 47.2 44.9 TULP3 TUBL3 ENSG00000078246 "TUB like protein 3" O75386 12 2877223-2941138 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015285, HPA018496" Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA015285: AB_1858460, HPA018496: AB_2669889" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.99e-4)" "unprognostic (2.45e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.44e-1)" "unprognostic (4.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (7.52e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-2)" "unprognostic (3.19e-2)" 21.0 17.1 13.6 7.5 14.2 2.6 18.3 19.2 16.1 33.3 15.8 21.6 5.4 23.2 11.7 17.8 24.3 12.1 17.7 13.8 13.2 17.3 9.0 13.5 6.1 16.3 14.8 37.7 9.6 13.3 12.3 13.7 13.8 15.4 8.2 12.7 13.0 13.9 10.4 25.7 10.5 18.2 14.5 9.4 15.5 13.0 14.4 9.4 15.5 9.7 8.1 16.7 24.1 17.1 22.6 18.8 35.0 29.1 34.3 51.0 32.9 34.5 57.5 36.4 40.2 24.0 20.4 16.7 5.1 51.2 31.2 18.5 21.1 22.2 42.0 21.7 15.4 10.0 23.4 15.5 44.3 10.8 11.1 30.1 25.7 55.3 74.9 44.6 28.6 20.8 9.7 15.1 31.0 20.3 16.1 9.4 47.4 17.8 13.7 16.8 34.2 6.3 22.9 18.7 8.8 23.4 30.1 17.8 19.9 63.4 22.2 10.5 23.0 26.6 32.0 54.7 33.9 4.7 6.0 14.3 26.9 5.9 41.5 0.0 0.9 0.3 2.1 0.8 3.5 1.6 1.7 2.2 0.7 1.8 2.0 2.8 0.4 2.7 0.5 1.6 3.3 1.0 13.6 14.2 19.2 16.1 13.8 13.2 16.3 14.8 13.8 14.5 14.4 17.1 12.9 6.4 10.5 70.5 6.2 20.3 16.9 14.8 26.2 6.1 9.9 12.2 8.0 18.6 15.9 1.8 2.1 9.4 6.0 4.6 23.5 17.3 5.8 35.1 33.5 15.2 3.6 6.1 6.0 7.3 10.6 31.7 6.6 14.6 0.0 11.5 24.3 5.5 5.3 40.4 10.8 4.0 14.2 2.5 8.6 3.6 40.7 5.4 19.6 14.0 6.7 50.7 12.3 10.1 34.9 11.1 2.4 24.8 8.3 23.3 3.2 21.9 47.4 10.0 39.5 22.3 26.3 38.0 50.8 22.2 20.2 11.6 6.5 13.3 6.4 13.2 TWIST1 "ACS3, bHLHa38, BPES2, BPES3, CRS, CRS1, H-twist, SCS, TWIST" ENSG00000122691 "Twist family bHLH transcription factor 1" Q15672 7 19020991-19117636 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 25.2" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 92.8;Fibroblasts: 73.4;Langerhans cells: 30.3;Smooth muscle cells: 34.4;Theca cells: 29.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "SH-SY5Y: 263.5" "Low region specificity" "Detected in single" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.58e-2)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (3.62e-1)" "unprognostic (1.29e-2)" "unprognostic (9.80e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-2)" "unprognostic (8.51e-3)" "unprognostic (5.91e-2)" "unprognostic (8.99e-3)" "unprognostic (3.69e-1)" "unprognostic (1.29e-9)" "unprognostic (8.55e-3)" "unprognostic (1.54e-1)" "unprognostic (6.83e-3)" "unprognostic (1.97e-2)" 22.1 4.9 2.2 1.3 1.8 0.0 25.2 1.5 2.6 6.4 2.7 2.7 0.0 18.9 0.6 5.9 3.0 7.2 4.5 1.9 1.6 0.8 0.2 0.6 2.4 1.8 2.3 6.4 0.4 0.2 7.1 12.6 2.0 2.7 0.4 0.0 8.1 0.8 1.5 16.0 0.7 5.0 1.8 0.0 5.4 2.7 2.0 0.5 3.7 1.9 1.6 8.3 5.0 2.2 1.6 2.0 8.9 0.0 45.0 18.4 0.2 38.3 17.8 28.9 37.7 0.0 0.0 0.0 4.0 32.0 6.9 0.0 3.7 3.0 19.0 8.5 10.1 0.0 3.9 0.0 26.8 10.0 0.1 44.8 9.9 6.0 15.7 8.6 0.0 0.5 0.0 0.0 31.0 0.0 0.0 0.5 3.9 0.0 15.7 0.0 0.0 0.0 0.0 0.0 15.9 263.5 6.2 0.0 8.2 5.6 0.8 12.4 0.2 35.5 0.1 28.3 6.6 0.0 0.0 0.0 19.4 0.0 45.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.8 1.5 2.6 1.9 1.6 1.8 2.3 2.0 1.8 2.0 2.2 10.3 0.0 0.0 0.7 0.1 12.5 0.2 2.9 1.8 0.0 0.5 3.3 0.9 0.0 0.5 0.0 0.0 0.3 0.1 0.1 1.9 0.0 0.2 11.5 92.8 3.8 0.0 0.0 5.2 0.0 0.2 73.4 0.0 13.3 0.0 2.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 30.3 0.8 2.1 0.9 12.4 7.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.3 0.3 0.0 1.6 34.4 0.5 4.7 0.6 8.5 1.4 2.2 29.9 0.1 0.4 TXNIP "ARRDC6, EST01027, HHCPA78, THIF, VDUP1" ENSG00000265972 "Thioredoxin interacting protein" Q9H3M7 1 145992435-145996579 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 2550.5;NK-cells: 2028.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 951.8;HSkMC: 1276.5;hTCEpi: 664.0;hTERT-RPE1: 781.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031085, HPA053694" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "HPA031085: AB_10601706, HPA053694: AB_2682232" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.92e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (2.51e-1)" "unprognostic (9.23e-2)" "unprognostic (1.20e-1)" "unprognostic (3.65e-2)" "unprognostic (1.19e-1)" "unprognostic (8.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (8.19e-2)" "unprognostic (2.22e-3)" 1542.7 466.8 130.3 566.5 159.9 404.7 1396.7 137.1 158.5 846.0 133.8 965.4 223.3 811.8 381.2 428.7 730.3 395.0 745.2 120.3 136.6 532.6 204.0 841.9 800.8 182.0 144.9 382.9 580.5 634.0 192.3 594.0 185.4 352.4 487.5 14.5 567.0 554.5 1446.1 1060.4 810.7 658.7 157.1 946.4 713.4 106.4 159.2 373.7 556.6 2306.2 1068.8 740.9 638.7 217.3 56.5 0.2 13.0 0.9 291.6 951.8 29.7 66.0 131.3 58.5 79.7 35.3 74.6 15.8 379.6 18.1 9.7 15.0 13.0 124.8 154.8 74.2 7.1 45.7 20.2 32.6 13.8 189.7 91.7 1276.5 664.0 119.0 206.7 781.9 23.2 61.8 184.8 121.2 30.2 76.5 31.9 180.2 36.3 112.5 48.5 28.5 107.8 498.3 151.6 122.8 61.7 99.9 283.1 80.5 239.0 26.2 29.1 266.6 56.5 160.1 10.0 304.2 108.7 169.3 170.7 13.8 39.3 86.6 86.3 1059.6 571.2 1219.2 792.2 551.3 729.8 519.3 668.8 710.4 334.4 542.4 650.2 708.5 1246.6 637.1 496.3 154.8 674.5 1684.4 130.3 159.9 137.1 158.5 120.3 136.6 182.0 144.9 185.4 157.1 159.2 217.3 2550.5 227.6 328.5 26.4 1360.4 70.7 236.9 129.8 413.8 6.5 167.4 111.2 526.0 185.8 184.4 272.2 29.2 5.0 1004.6 578.0 450.0 79.7 8.3 179.8 594.5 740.2 164.2 270.8 0.2 53.8 4.1 666.5 160.5 464.2 377.4 53.6 349.8 114.8 231.9 6.7 0.5 320.9 136.3 845.1 184.9 35.5 654.5 730.8 108.5 36.5 892.0 3.6 2028.9 45.2 55.8 225.7 459.4 447.2 639.6 370.7 79.0 169.3 155.8 3.7 1196.5 452.4 398.7 7.6 63.7 160.1 72.2 10.9 1142.8 303.9 186.9 516.2 UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561506-162599842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 678.4;U-251 MG: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No Yes 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: AB_1857409" "unprognostic (2.32e-2)" "unprognostic (2.45e-1)" "unprognostic (2.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.71e-2)" "unprognostic (1.46e-2)" "unprognostic (1.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (4.96e-2)" "prognostic unfavorable (5.12e-5)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (3.51e-1)" "unprognostic (3.45e-2)" 96.0 43.7 12.2 33.7 13.2 51.5 58.8 13.5 14.9 37.1 16.1 65.6 43.9 18.6 29.1 33.9 33.1 39.8 45.1 13.4 13.6 27.0 172.6 36.0 14.1 11.5 16.9 39.9 68.6 12.0 28.9 22.3 11.8 33.3 66.3 20.4 76.6 31.2 41.2 25.0 56.0 24.6 11.6 13.8 55.8 90.9 13.9 11.8 24.4 45.2 22.2 77.9 37.4 11.0 204.6 14.6 39.2 31.5 185.7 147.8 26.8 292.4 107.1 220.7 178.5 38.6 93.5 8.0 64.3 225.8 79.6 35.0 44.7 85.5 359.9 32.4 66.6 36.0 43.8 75.6 87.1 61.8 23.5 69.0 39.8 242.4 678.4 100.6 137.5 62.6 206.1 81.3 298.9 37.4 36.0 40.0 29.2 207.6 64.4 31.9 76.2 99.8 34.8 23.7 41.9 43.4 128.0 78.4 70.4 45.6 38.9 70.0 235.2 110.6 102.5 281.2 463.5 135.0 51.0 67.0 63.4 28.5 71.3 1.4 2.2 11.7 16.7 2.1 20.4 10.7 10.0 17.3 4.6 11.1 9.4 12.0 2.2 8.6 1.2 7.7 5.5 7.2 12.2 13.2 13.5 14.9 13.4 13.6 11.5 16.9 11.8 11.6 13.9 11.0 58.1 6.4 30.2 15.0 42.5 134.7 163.0 47.2 47.8 11.8 59.1 42.7 30.0 27.1 57.4 16.5 8.4 27.2 82.9 94.8 72.4 27.1 78.2 28.6 58.0 35.7 54.9 13.9 12.4 64.7 63.9 195.8 45.9 40.7 33.7 21.3 22.5 98.4 14.5 6.7 12.4 139.4 40.7 10.1 82.2 20.1 50.7 24.6 85.4 3.7 18.2 16.6 41.2 8.0 6.1 73.0 74.5 41.3 152.8 94.6 88.4 26.9 56.0 13.9 19.7 59.4 88.6 212.0 125.9 43.2 81.8 97.7 50.5 18.8 70.4 141.7 UBTD2 "DC-UbP, MGC30022" ENSG00000168246 "Ubiquitin domain containing 2" Q8WUN7 5 172209646-172283764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 76.1;Late spermatids: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035891, HPA035892" Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA035891: AB_2674846, HPA035892: AB_10670670" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "prognostic favorable (5.92e-5)" "unprognostic (3.45e-2)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.50e-2)" "unprognostic (1.08e-1)" "unprognostic (9.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (5.92e-2)" "unprognostic (5.12e-2)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.52e-1)" 13.5 11.4 7.6 8.7 9.0 1.6 17.5 24.7 9.5 24.6 8.7 15.0 18.4 21.0 9.3 10.6 12.0 16.1 10.3 7.9 8.4 15.6 15.7 13.2 9.2 8.4 8.2 21.1 12.5 11.1 7.0 17.1 8.3 13.4 15.8 9.2 11.9 12.7 9.8 9.9 22.1 17.9 7.9 7.2 12.2 35.4 7.8 12.0 11.5 15.7 10.2 14.5 11.3 8.3 21.9 16.7 78.1 61.0 48.1 42.9 38.0 27.8 33.2 29.9 43.8 36.5 15.9 18.7 23.5 43.6 51.4 15.1 41.7 30.3 40.1 18.0 30.3 5.7 17.6 28.4 32.6 13.3 10.3 33.1 37.1 31.9 25.7 25.8 36.5 28.8 2.3 7.5 28.6 23.8 23.7 27.8 33.4 19.0 21.1 43.5 38.0 7.2 36.3 23.0 22.9 57.9 30.1 27.0 28.4 39.9 23.3 21.7 26.6 39.6 29.2 21.0 23.9 6.8 19.9 17.8 13.9 18.2 31.0 0.0 0.3 0.0 0.2 0.4 0.3 0.2 0.2 0.1 0.4 0.2 0.3 0.2 0.0 0.1 0.2 0.7 0.5 0.1 7.6 9.0 24.7 9.5 7.9 8.4 8.4 8.2 8.3 7.9 7.8 8.3 15.2 6.4 4.8 14.0 3.7 22.0 25.7 12.8 15.9 8.4 22.2 12.1 5.5 11.5 11.9 9.2 0.0 9.8 5.6 22.8 17.6 14.5 76.1 9.7 28.3 12.3 8.9 0.0 14.9 12.0 21.7 31.4 8.6 23.6 0.0 14.2 13.9 15.1 6.8 25.2 22.5 12.2 14.2 6.5 44.5 130.9 24.8 9.8 14.2 9.4 5.8 16.2 1.0 25.6 19.8 21.6 9.8 21.1 2.9 29.8 20.5 17.2 6.8 3.4 6.6 16.7 19.6 5.8 9.7 17.0 18.8 8.1 4.0 11.9 13.7 39.6 USP33 "KIAA1097, VDU1" ENSG00000077254 "Ubiquitin specific peptidase 33" Q8TEY7 1 77695987-77759852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005719 Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 36: HEL - Hemostasis" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Golgi apparatus" "HPA005719: AB_10601708" "unprognostic (2.31e-3)" "unprognostic (2.73e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (9.19e-3)" "unprognostic (1.88e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.59e-1)" "unprognostic (5.36e-3)" "unprognostic (4.89e-2)" "unprognostic (5.76e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" 40.7 31.2 31.5 24.6 40.4 34.5 34.3 52.0 49.7 24.2 37.3 24.3 25.4 28.0 26.8 21.6 22.5 26.3 21.7 35.4 31.8 31.1 25.4 26.2 28.1 28.6 24.9 29.3 19.5 35.0 20.9 28.0 30.8 28.8 25.2 49.1 25.2 22.9 18.0 24.3 26.9 24.1 22.3 26.0 24.4 25.4 28.6 27.1 30.4 20.7 26.0 22.9 20.0 55.5 42.4 18.8 64.1 44.2 90.0 78.3 54.8 45.3 42.9 54.0 60.1 25.4 35.5 31.4 41.2 44.3 88.2 32.1 47.4 31.1 65.7 28.8 36.6 111.1 44.6 22.2 56.0 37.8 26.8 58.3 23.9 52.4 37.9 51.9 48.7 28.0 43.9 26.3 41.2 16.1 34.9 38.0 62.2 32.6 37.2 33.0 67.7 22.2 51.0 41.1 53.8 41.2 31.9 41.5 64.2 54.3 23.1 41.2 41.2 49.4 34.4 50.1 43.2 21.0 28.4 30.4 37.3 44.5 25.4 67.3 22.5 31.8 21.0 22.6 21.7 20.5 20.6 21.7 17.5 22.3 24.5 21.9 30.5 19.2 30.1 18.4 20.7 16.7 31.5 40.4 52.0 49.7 35.4 31.8 28.6 24.9 30.8 22.3 28.6 55.5 40.2 44.8 40.9 66.3 35.1 17.2 18.8 21.2 32.5 56.7 25.7 22.1 39.9 22.8 25.5 35.0 58.4 25.1 48.8 35.9 9.8 20.8 4.3 54.8 37.8 31.8 35.5 50.9 149.3 15.4 19.0 39.6 43.3 54.6 23.4 43.1 28.2 23.1 19.0 62.2 159.0 28.6 22.4 30.8 20.7 5.5 35.8 35.1 23.2 75.9 38.7 31.4 37.0 98.0 138.5 19.6 27.8 32.0 42.4 22.9 33.2 25.6 37.3 44.5 19.7 34.9 35.6 39.8 30.1 28.4 16.3 11.9 41.0 39.2 24.8 21.8 UTP14C "2700066J21Rik, KIAA0266" ENSG00000253797 "UTP14C small subunit processome component" Q5TAP6 13 52024691-52033600 "Predicted intracellular proteins" "Differentiation, Meiosis, Ribosome biogenesis, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.2;JURKAT: 2.2;MOLT-4: 1.3;NB-4: 5.7;RPTEC TERT1: 2.1;THP-1: 2.9" "HPA047217, HPA054023" Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA047217: AB_2679987, HPA054023: AB_2682346" "unprognostic (7.89e-2)" "unprognostic (5.98e-2)" "unprognostic (4.47e-1)" "unprognostic (1.25e-1)" "unprognostic (2.33e-3)" "unprognostic (2.51e-1)" "unprognostic (2.02e-1)" "unprognostic (3.30e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (7.35e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.46e-5)" "unprognostic (2.44e-2)" "unprognostic (3.43e-1)" "unprognostic (1.74e-1)" "unprognostic (3.04e-2)" 5.7 5.2 3.8 0.0 3.5 0.0 5.2 3.6 4.4 5.9 4.0 6.1 0.3 7.1 0.0 4.4 5.9 0.0 6.2 3.4 3.5 5.9 7.7 4.7 0.6 3.3 3.9 5.5 6.8 1.2 5.5 0.0 3.3 5.3 0.0 2.2 6.6 0.0 6.7 3.7 5.6 0.2 3.3 5.1 5.9 3.2 3.7 1.8 6.1 2.4 0.0 5.5 5.1 3.8 0.0 0.0 1.2 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.2 1.3 5.7 0.0 0.0 0.0 0.5 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.5 3.6 4.4 3.4 3.5 3.3 3.9 3.3 3.3 3.7 3.8 9.9 6.4 17.5 8.5 8.2 5.9 5.6 10.8 9.6 13.9 13.7 7.9 23.8 12.8 15.8 16.5 4.2 10.1 5.1 21.2 0.0 7.3 0.4 9.1 13.9 13.9 18.6 19.9 8.9 7.6 9.6 13.9 5.1 12.4 11.4 14.4 14.6 33.6 9.3 25.2 9.0 14.7 8.2 13.5 3.9 0.8 10.5 8.1 8.8 5.6 8.2 14.1 10.3 6.6 10.7 7.7 11.3 14.3 8.4 12.7 9.9 6.4 14.8 11.6 6.6 20.2 12.6 7.2 13.3 14.0 8.4 7.0 7.2 9.4 14.1 6.7 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.9;Muller glia cells: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 209.8 82.0 45.7 12.0 51.3 3.9 151.3 41.8 53.1 103.6 48.2 151.5 12.1 99.9 7.2 50.8 72.5 19.2 253.3 38.7 45.1 84.6 44.0 82.5 14.4 54.8 47.4 82.6 84.9 18.3 104.2 9.8 45.0 92.7 4.7 12.7 57.7 28.5 143.8 77.3 59.5 10.2 44.2 55.9 89.2 17.5 50.6 6.6 83.7 51.5 9.1 118.0 77.5 37.3 15.4 25.9 9.9 28.1 49.7 36.8 12.7 14.7 27.8 13.1 16.0 13.8 31.7 19.8 28.6 14.0 28.8 20.8 15.8 11.5 2.3 20.6 15.1 16.7 33.9 13.3 45.4 4.8 20.1 39.6 12.0 19.6 12.2 33.9 18.4 20.6 20.2 32.5 22.2 31.8 27.4 12.6 7.0 10.9 22.3 32.1 20.5 46.5 11.0 19.5 14.0 46.4 12.4 38.1 57.4 7.6 25.1 5.6 13.0 50.8 30.2 23.1 8.7 90.5 45.5 15.4 41.6 5.3 25.1 0.3 0.2 0.6 0.9 0.0 0.8 3.0 0.8 0.9 0.4 2.4 0.9 1.6 0.0 0.4 0.0 30.5 0.5 0.4 45.7 51.3 41.8 53.1 38.7 45.1 54.8 47.4 45.0 44.2 50.6 37.3 54.1 19.2 32.6 43.8 27.6 12.7 6.7 10.1 2.2 47.9 32.8 65.7 204.9 10.0 7.6 14.7 33.3 9.6 68.3 11.9 39.2 14.8 1.1 24.2 47.7 21.9 53.3 4.4 7.3 12.9 16.8 68.6 5.1 31.6 18.4 62.7 19.6 9.8 51.4 65.6 26.6 12.2 20.3 31.5 21.5 3.5 60.9 50.0 35.6 19.7 17.7 130.6 12.3 29.1 11.8 14.5 7.3 109.1 12.3 11.5 20.3 31.6 8.9 39.6 6.6 47.4 53.7 0.5 1.2 6.4 13.9 8.9 19.0 34.3 12.8 7.5 VEGFD "FIGF, VEGF-D" ENSG00000165197 "Vascular endothelial growth factor D" O43915 X 15345596-15384413 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 42.7" "Cell type enriched" "Detected in some" 12 "Fibroblasts: 39.8" "Cancer enhanced" "Detected in some" "liver cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.4;ASC TERT1: 2.8;EFO-21: 1.3;HSkMC: 2.8" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 3.5;hippocampal formation: 3.3;white matter: 2.6" "Not detected" "Not detected" HPA027342 Uncertain "Secreted to blood" NA NA 592000 450000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA027342: AB_1848597" "unprognostic (5.90e-2)" "unprognostic (9.79e-3)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-1)" "unprognostic (6.06e-3)" "unprognostic (5.57e-2)" "unprognostic (2.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.59e-5)" "unprognostic (3.08e-2)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (1.75e-2)" 11.4 9.9 1.8 0.7 1.8 0.0 20.3 1.5 2.3 19.2 1.5 5.0 1.2 3.8 4.9 2.7 4.1 2.8 15.5 1.6 2.0 1.7 1.5 42.7 0.4 1.8 1.7 4.4 0.7 2.7 7.0 0.2 2.0 1.5 2.0 0.3 2.3 1.8 17.6 1.2 4.2 3.3 1.3 2.8 5.8 0.6 2.1 0.3 1.5 23.0 1.3 6.0 8.1 2.0 0.0 0.6 0.5 0.9 3.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.3 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.3 2.8 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.3 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.5 2.3 1.6 2.0 1.8 1.7 2.0 1.3 2.1 2.0 3.1 3.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 39.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.3 1.6 0.0 0.0 VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 68.3;Fibroblasts: 58.8;Granulosa cells: 45.1;Leydig cells: 115.2;Skeletal myocytes: 45.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "ASC diff: 33.6;ASC TERT1: 65.2;BJ: 32.9;fHDF/TERT166: 112.3;SuSa: 62.2;THP-1: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" 35.4 0.9 0.2 0.5 0.5 0.9 15.4 0.8 0.9 6.0 0.4 3.9 0.4 1.0 0.6 8.7 7.9 2.3 18.6 0.3 0.1 0.2 0.0 1.2 2.3 0.1 0.1 28.7 1.0 0.6 3.1 2.2 0.1 7.0 1.5 0.0 11.6 2.3 12.5 12.7 2.7 0.2 0.0 0.1 4.7 3.0 0.3 1.0 8.9 41.1 2.2 15.0 14.6 0.2 0.0 0.0 0.0 0.0 33.6 65.2 0.0 32.9 7.7 10.4 4.3 0.0 0.0 0.0 0.0 112.3 0.1 0.2 6.2 0.0 6.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.3 1.6 0.0 0.0 0.0 2.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.7 0.0 62.2 0.0 35.6 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 2.5 2.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.5 0.8 0.9 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.2 4.1 0.0 0.0 0.7 0.0 4.2 0.9 0.0 68.3 0.0 0.2 10.0 3.2 0.0 0.0 0.0 0.0 10.6 0.9 0.3 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.0 1.8 0.0 11.0 58.8 0.0 0.0 0.0 45.1 0.4 0.0 1.1 0.0 0.7 0.4 0.0 0.0 3.5 2.7 115.2 0.5 7.2 20.6 0.0 0.0 4.1 0.5 0.3 0.0 0.1 23.3 0.8 0.1 0.0 0.0 0.0 0.0 6.6 45.2 6.1 1.1 0.6 1.6 3.4 4.2 1.1 0.1 0.3 0.2 WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.3;Extravillous trophoblasts: 21.7;Fibroblasts: 4.8;Inhibitory neurons: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 7.3;T-47d: 8.2;U-266/84: 7.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA055048, HPA062539" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA055048: AB_2682683, HPA062539: AB_2684793" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" 1.5 0.2 13.1 1.5 14.9 1.2 0.6 4.2 17.9 0.8 3.2 1.4 1.4 0.3 1.5 1.4 1.0 0.5 1.5 15.3 7.3 0.4 0.4 1.1 1.7 8.6 7.6 0.2 0.3 0.1 2.4 0.3 8.2 0.8 0.7 0.1 0.9 0.6 0.7 3.4 4.3 0.1 5.1 4.1 1.1 3.3 10.4 1.9 1.0 0.4 1.5 1.3 1.0 9.8 1.9 1.2 0.0 1.7 0.0 0.0 4.6 1.3 2.4 0.5 0.1 3.6 4.0 0.0 0.3 0.2 1.5 2.2 4.8 0.3 0.2 1.1 6.3 2.1 1.7 0.1 0.0 0.7 2.9 0.0 0.4 0.1 2.1 4.1 0.0 1.5 7.3 0.3 0.7 2.4 0.1 2.5 0.0 1.3 2.5 0.0 0.6 2.2 0.0 0.4 0.1 0.0 0.3 0.1 0.6 2.2 8.2 2.7 0.0 2.5 4.9 0.4 0.6 2.6 7.8 0.0 1.0 5.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.9 4.2 17.9 15.3 7.3 8.6 7.6 8.2 5.1 10.4 9.8 0.2 0.0 0.0 0.7 0.2 0.4 0.0 0.0 1.8 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.8 0.2 0.1 0.0 0.0 0.0 7.3 0.0 21.7 4.8 0.0 0.1 0.0 0.0 0.7 0.0 0.3 0.0 4.7 0.2 0.0 0.0 1.2 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.7 3.0 0.9 1.3 1.4 1.6 0.0 0.0 0.1 WNT11 ENSG00000085741 "Wnt family member 11" O96014 11 76186325-76210736 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.4" "Group enriched" "Detected in some" 5 "Adipocytes: 41.5;Fibroblasts: 23.2;Theca cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 6 "NK-cells: 2.9" "Cell line enhanced" "Detected in some" "BEWO: 36.2;CACO-2: 12.1;CAPAN-2: 17.8;EFO-21: 57.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA050101 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA050101: AB_2681015" "prognostic favorable (5.97e-4)" "unprognostic (9.27e-2)" "unprognostic (2.01e-2)" "unprognostic (2.52e-1)" "unprognostic (1.87e-2)" "unprognostic (8.43e-2)" "unprognostic (7.88e-2)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (2.88e-2)" "unprognostic (4.36e-2)" "unprognostic (3.10e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (3.16e-3)" "unprognostic (1.09e-3)" 37.4 20.8 1.7 0.4 3.5 0.9 23.7 4.1 2.2 4.8 14.3 3.6 2.5 2.7 1.3 1.2 6.7 2.1 8.3 3.8 3.5 2.8 8.0 6.3 1.1 7.4 2.7 4.5 9.5 1.2 3.1 4.1 6.9 4.3 1.1 0.3 4.3 1.1 12.3 8.1 3.3 0.6 2.8 3.5 1.4 0.9 2.8 0.9 17.2 7.1 0.2 4.0 3.8 2.1 0.0 0.0 0.0 0.0 2.9 0.2 36.2 0.0 0.0 0.1 0.2 12.1 17.8 0.0 57.0 0.1 0.2 5.5 1.1 0.0 0.0 5.5 2.1 2.9 1.4 2.2 0.0 0.0 0.4 0.1 1.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 1.4 0.3 0.0 0.4 0.9 0.0 2.9 0.4 0.0 2.1 0.2 0.0 2.5 0.1 1.4 0.0 0.0 2.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.2 1.7 3.5 4.1 2.2 3.8 3.5 7.4 2.7 6.9 2.8 2.8 2.1 41.5 0.0 0.0 0.3 0.5 1.3 0.5 0.0 1.2 0.0 0.9 1.9 4.7 0.0 0.0 0.0 0.0 0.9 2.3 2.2 0.0 0.0 0.0 5.0 2.9 1.8 0.0 0.0 0.2 0.2 3.3 23.2 0.0 1.1 0.0 0.4 0.7 2.5 0.1 0.0 0.5 0.5 0.0 0.3 2.3 0.0 0.0 0.7 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 2.6 0.7 0.7 0.1 3.8 0.0 0.0 0.0 0.0 1.8 5.7 0.4 0.5 0.1 0.9 1.4 0.9 24.3 1.5 0.1 WNT9A WNT14 ENSG00000143816 "Wnt family member 9A" O14904 1 227918656-227947932 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.7;skeletal muscle: 26.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 5.1;Ionocytes: 6.1;Respiratory ciliated cells: 12.5;Urothelial cells: 5.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 16.2;PC-3: 10.8;RH-30: 16.4;SCLC-21H: 14.9;SiHa: 14.7;U-2197: 10.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.27e-2)" "unprognostic (3.24e-1)" "unprognostic (3.77e-3)" "unprognostic (4.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.39e-2)" "unprognostic (1.44e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.48e-1)" "unprognostic (1.38e-2)" "unprognostic (1.70e-2)" "unprognostic (3.72e-2)" "unprognostic (8.71e-2)" "unprognostic (5.04e-2)" "unprognostic (9.93e-2)" 3.3 1.4 0.4 1.1 0.6 0.1 3.0 0.6 0.8 4.1 7.7 18.7 1.3 5.3 0.4 5.8 5.5 2.1 10.1 0.7 0.9 0.9 0.2 3.9 0.3 1.2 0.9 9.8 2.8 1.2 2.8 2.1 2.1 2.5 1.1 0.0 2.4 1.0 26.3 1.1 6.0 4.3 0.5 1.0 5.9 1.5 0.7 1.1 2.0 2.8 0.3 4.9 3.4 0.5 1.0 3.3 0.4 0.1 0.4 0.7 8.1 1.1 0.9 0.1 0.0 0.0 8.8 0.0 4.7 1.5 3.3 16.2 0.4 0.8 0.0 1.6 0.6 0.0 6.0 0.2 0.4 0.0 0.5 0.1 4.0 0.1 0.1 0.3 1.0 0.0 0.0 0.1 1.8 2.2 0.0 0.0 1.0 0.0 10.8 0.2 16.4 1.7 4.6 1.1 14.9 0.0 14.7 6.6 0.0 5.2 8.4 1.8 0.6 2.1 1.3 10.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.6 0.8 0.7 0.9 1.2 0.9 2.1 0.5 0.7 0.5 0.3 3.2 0.6 0.3 0.0 0.9 1.3 3.6 0.0 0.0 3.1 1.3 1.4 0.0 4.3 1.8 0.0 0.3 0.2 0.8 0.0 0.7 0.1 2.1 2.1 0.4 3.0 0.0 0.7 1.3 0.2 5.1 1.5 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 2.9 6.1 0.0 0.4 0.1 4.4 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.9 1.1 0.0 4.5 0.1 1.8 0.1 0.1 12.5 0.0 0.0 1.3 1.1 0.0 1.8 3.9 0.3 0.0 0.2 0.1 0.1 5.3 XG PBDX ENSG00000124343 "Xg glycoprotein (Xg blood group)" P55808 X 2752040-2816500 "Blood group antigen proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.5;skin 1: 38.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.4;Basal respiratory cells: 15.1;Basal squamous epithelial cells: 30.7;Fibroblasts: 30.1;Melanocytes: 10.6;Squamous epithelial cells: 10.1;Suprabasal keratinocytes: 21.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 63.7;ASC TERT1: 50.6;fHDF/TERT166: 31.5;hTCEpi: 49.6;T-47d: 28.2" "Low region specificity" "Detected in all" NA NA 22000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "prognostic unfavorable (4.25e-4)" "unprognostic (1.69e-2)" "unprognostic (1.40e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (3.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" "unprognostic (8.62e-2)" "unprognostic (7.21e-2)" "unprognostic (2.30e-1)" "unprognostic (8.10e-6)" "unprognostic (3.96e-3)" "unprognostic (7.98e-2)" "unprognostic (5.83e-3)" "unprognostic (6.77e-3)" 17.5 0.0 0.0 0.1 0.0 1.2 8.9 0.1 0.0 12.0 0.0 0.3 0.1 1.2 0.0 11.7 0.8 3.3 2.6 0.1 0.1 0.3 0.7 0.6 0.3 0.3 0.2 0.2 0.1 0.1 0.1 1.8 0.2 0.8 0.1 0.0 7.6 0.6 3.2 38.6 0.1 0.2 0.3 0.1 0.3 0.1 0.0 2.2 1.9 5.0 3.1 2.1 12.7 0.7 0.1 0.0 0.0 0.1 63.7 50.6 0.6 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 31.5 0.0 5.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.1 49.6 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.2 4.2 0.1 28.2 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.2 0.2 0.3 0.0 0.7 3.3 0.0 0.0 1.0 0.0 14.4 0.5 15.1 30.7 0.0 0.2 0.4 0.4 0.0 1.3 1.8 0.0 0.8 0.5 0.0 0.0 0.0 0.0 2.4 0.5 0.8 0.0 1.3 0.9 0.0 0.1 30.1 0.0 1.2 0.0 6.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 9.0 0.0 0.0 0.1 10.6 1.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 2.5 2.5 0.2 0.5 10.1 21.9 0.5 0.5 0.5 0.0 0.2 ZBTB16 "PLZF, ZNF145" ENSG00000109906 "Zinc finger and BTB domain containing 16" Q05516 11 114059711-114256765 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 105.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.8;Inhibitory neurons: 125.9;NK-cells: 119.4;Skeletal myocytes: 163.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 23.3;MAIT T-cell: 39.4;naive B-cell: 11.0;NK-cell: 10.9" "Group enriched" "Detected in many" 5 "B-cells: 11.0;NK-cells: 10.9;T-cells: 39.4" "Cell line enhanced" "Detected in some" "ASC diff: 71.5;ASC TERT1: 38.6;HEL: 40.7;HHSteC: 26.6;HSkMC: 26.7;hTCEpi: 30.6;hTERT-HME1: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001499, CAB004540" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB004540: AB_2218941, HPA001499: AB_1079640" "unprognostic (2.21e-1)" "unprognostic (2.17e-1)" "unprognostic (7.30e-2)" "unprognostic (1.18e-1)" "unprognostic (2.53e-1)" "unprognostic (3.05e-1)" "unprognostic (1.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-4)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.21e-4)" "unprognostic (2.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" 55.8 20.8 5.1 3.4 14.9 7.6 32.3 11.7 24.8 25.9 17.7 20.9 0.9 29.6 4.0 28.1 30.9 13.1 28.1 9.9 8.4 10.6 14.5 27.1 8.8 20.1 8.4 51.4 61.7 34.3 6.4 9.6 15.2 15.1 3.3 2.2 13.3 7.0 88.6 28.5 16.3 15.8 4.9 13.2 18.3 4.0 7.1 6.5 29.3 105.8 2.0 29.4 19.7 18.0 0.0 0.0 13.0 0.0 71.5 38.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 40.7 0.0 0.0 26.6 0.9 0.7 26.7 30.6 0.0 25.6 0.0 4.6 5.5 0.1 0.0 0.8 0.0 2.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 4.2 1.2 23.3 1.2 39.4 0.4 1.2 3.5 0.1 11.0 1.3 0.6 0.3 10.9 1.2 0.0 0.4 5.7 5.1 14.9 11.7 24.8 9.9 8.4 20.1 8.4 15.2 4.9 7.1 18.0 95.3 22.4 7.7 59.1 16.3 11.1 81.7 7.7 8.6 32.6 12.6 16.8 35.1 42.9 7.1 9.2 0.0 0.1 51.2 0.7 1.9 1.9 21.1 1.7 41.3 49.5 7.2 18.1 134.8 0.9 0.2 59.8 1.1 3.8 14.5 38.2 65.7 50.9 0.8 0.0 125.9 3.7 8.2 27.0 5.3 27.7 89.8 32.1 7.2 65.6 7.6 20.2 119.4 45.8 43.4 0.3 0.1 92.2 17.7 38.6 28.8 6.6 6.8 1.9 105.2 163.9 75.3 0.4 9.9 1.8 6.8 0.3 27.8 0.2 3.5 9.4 ZDHHC9 "CGI-89, CXorf11, DHHC9, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type palmitoyltransferase 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 66.0;Oligodendrocytes: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: AB_10610700" "prognostic unfavorable (9.77e-5)" "prognostic unfavorable (4.64e-5)" "unprognostic (2.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.01e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-1)" "unprognostic (3.49e-2)" "unprognostic (9.70e-3)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-2)" "unprognostic (4.11e-2)" 28.2 12.0 39.2 10.2 66.6 5.4 24.3 46.5 52.5 19.1 23.3 22.0 31.6 11.8 11.7 15.6 12.1 15.3 15.5 39.2 49.0 37.1 40.1 26.7 3.3 60.5 58.2 11.2 25.9 25.2 11.4 17.2 52.5 18.8 24.9 6.0 21.1 11.3 13.4 35.3 34.0 15.3 44.8 3.9 19.5 4.1 57.8 3.6 13.8 11.3 6.6 23.8 14.5 78.6 45.9 23.8 33.2 67.5 112.4 87.7 27.0 44.3 50.6 20.9 26.0 37.6 58.4 1.6 73.7 47.6 54.0 30.4 38.0 44.6 30.0 2.6 23.7 9.2 24.0 50.1 44.4 6.1 15.7 96.0 71.1 34.0 50.1 36.5 39.9 15.0 10.1 17.6 34.0 40.0 8.8 11.4 18.0 102.3 40.4 8.2 21.4 27.1 30.1 25.2 26.3 22.0 12.7 64.7 20.5 38.9 27.6 10.1 32.8 21.1 7.3 50.0 36.3 16.5 12.7 5.5 37.9 25.1 10.8 0.0 2.2 1.8 3.0 2.0 3.7 2.7 3.6 2.9 2.4 1.5 4.5 2.6 0.0 2.5 5.2 5.1 1.8 2.1 39.2 66.6 46.5 52.5 39.2 49.0 60.5 58.2 52.5 44.8 57.8 78.6 66.0 22.4 28.6 4.6 2.8 18.6 12.4 12.8 13.1 9.1 16.8 15.1 4.6 17.2 15.9 46.0 2.1 5.6 2.7 20.1 3.9 18.6 1.8 23.8 16.9 16.6 18.0 4.2 10.5 19.8 19.1 32.7 18.3 59.7 2.5 11.5 7.9 43.7 4.9 1.7 11.8 23.2 10.2 3.5 12.2 2.0 12.2 3.9 10.6 7.5 0.3 1.5 1.0 9.5 118.2 33.5 14.6 7.5 7.7 39.1 51.0 25.8 7.2 2.8 0.0 9.5 11.1 8.4 8.7 16.9 19.2 10.3 5.1 7.5 27.2 22.1 ZFP36 "G0S24, NUP475, RNF162A, TIS11, TTP" ENSG00000128016 "ZFP36 ring finger protein" P26651 19 39406847-39409412 "Predicted intracellular proteins" "Host-virus interaction, mRNA transport, RNA-mediated gene silencing, Transport" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 2759.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 154.7;hTCEpi: 179.0;Karpas-707: 167.0;U-266/84: 149.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 151.4" HPA006009 Approved Approved "Intermediate filaments" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA006009: AB_1859030" "unprognostic (2.30e-2)" "unprognostic (2.27e-1)" "unprognostic (8.26e-2)" "unprognostic (6.76e-2)" "unprognostic (4.74e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (4.59e-2)" "unprognostic (5.20e-1)" "unprognostic (3.61e-3)" "unprognostic (9.44e-2)" "unprognostic (3.11e-1)" "unprognostic (4.20e-3)" "unprognostic (5.22e-3)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (6.92e-3)" 1520.5 341.7 46.9 258.1 49.9 745.3 716.3 55.6 74.0 517.1 71.2 582.4 168.3 316.1 17.0 645.5 1276.8 520.0 575.4 42.8 84.3 288.1 462.0 1135.1 175.1 130.5 63.1 480.5 160.6 124.5 311.5 120.9 68.5 342.3 175.6 39.2 329.7 143.6 322.8 828.9 322.5 426.0 78.8 282.1 554.4 49.4 86.3 269.6 510.2 281.6 73.1 523.2 712.5 79.6 27.5 16.5 4.3 1.5 108.8 154.7 7.7 20.8 26.7 11.2 8.7 12.8 28.3 16.8 6.2 32.7 12.1 13.2 1.0 35.0 3.5 21.1 1.6 7.2 12.1 8.0 70.2 7.4 41.6 56.7 179.0 8.0 66.3 14.6 6.6 18.7 10.2 167.0 19.4 21.5 13.2 17.7 1.6 83.4 2.6 18.9 2.3 35.9 14.9 43.6 1.2 4.2 10.1 23.6 6.1 6.3 16.8 39.8 11.4 15.3 6.1 28.2 6.3 116.5 149.7 19.5 15.4 15.1 6.4 121.8 72.2 68.8 38.8 69.9 32.8 47.8 33.4 39.5 69.0 45.5 38.0 37.0 313.6 17.4 95.5 50.9 41.9 44.3 46.9 49.9 55.6 74.0 42.8 84.3 130.5 63.1 68.5 78.8 86.3 79.6 2759.0 419.9 864.0 7.5 686.2 1160.4 1543.0 789.3 2108.6 0.4 819.5 566.2 514.9 351.8 426.9 80.9 4.2 70.3 962.4 628.2 31.3 234.2 6.1 528.1 797.5 1208.6 631.9 109.2 0.4 105.6 95.5 2072.6 881.3 1055.0 690.7 45.7 668.6 206.4 703.1 1.7 0.2 608.3 250.3 669.9 2332.1 17.4 557.7 1189.0 631.5 24.4 125.6 55.0 94.7 0.0 1.6 156.4 907.8 139.5 1540.1 823.3 1060.8 60.2 298.5 7.1 769.2 878.2 1346.7 2.9 5.4 1641.6 1585.6 154.2 1193.0 87.1 366.5 639.9 ZIC1 "ZIC, ZNF201" ENSG00000152977 "Zic family member 1" Q15915 3 147393422-147510293 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Craniosynostosis, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 616.8" "Group enriched" "Detected in some" 4 "Microglial cells: 25.3;Skeletal myocytes: 61.0" "Cancer enhanced" "Detected in many" "glioma: 9.5" "Region enriched" "Detected in all" 5 "cerebellum: 616.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 174.0;MCF7: 43.9;U-2197: 28.5" "Region enhanced" "Detected in all" "cerebellum: 207.4" "Region enriched" "Detected in all" 8 "cerebellum: 638.1" HPA004098 Supported Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA004098: AB_1859065" "unprognostic (1.33e-2)" "unprognostic (1.82e-1)" "unprognostic (4.01e-2)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-2)" "unprognostic (2.19e-1)" "unprognostic (5.01e-1)" "unprognostic (2.61e-7)" "unprognostic (2.95e-3)" "unprognostic (1.67e-2)" "unprognostic (3.01e-1)" 3.4 0.7 25.0 0.0 50.7 0.0 0.2 616.8 30.3 0.0 39.0 0.1 0.2 0.0 1.8 0.2 0.0 0.1 0.1 13.6 39.5 0.1 12.8 0.1 0.1 66.8 55.3 0.2 0.1 0.0 2.4 0.0 67.3 0.0 0.1 10.7 0.5 0.0 6.9 2.5 0.8 0.0 23.8 0.0 0.2 0.3 112.1 0.0 0.0 0.8 0.0 0.0 0.0 44.8 0.0 0.0 174.0 0.0 17.9 19.6 9.8 11.4 13.5 12.1 9.9 0.0 0.0 0.0 9.1 0.9 9.2 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.4 0.0 0.7 0.0 0.0 3.1 0.0 10.9 43.9 0.0 0.0 0.5 0.9 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 10.7 0.0 0.0 0.0 0.0 17.9 0.0 28.5 11.0 0.0 0.0 0.0 13.5 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 50.7 616.8 30.3 13.6 39.5 66.8 55.3 67.3 23.8 112.1 44.8 0.2 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.3 0.9 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.1 0.0 25.3 0.0 4.3 0.0 2.0 9.5 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 61.0 0.3 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 ZNF181 "HHZ181, MGC44316" ENSG00000197841 "Zinc finger protein 181" Q2M3W8 19 34734155-34745378 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA043701, HPA062305" Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA043701: AB_10960859, HPA062305: AB_2684743" "unprognostic (2.00e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-4)" "unprognostic (1.06e-1)" "unprognostic (4.83e-3)" "unprognostic (5.60e-2)" "unprognostic (2.28e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.01e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.06e-1)" "unprognostic (6.52e-2)" "unprognostic (2.60e-1)" "unprognostic (1.13e-1)" "unprognostic (9.34e-2)" "prognostic favorable (5.45e-4)" 7.5 8.9 10.4 5.9 12.5 3.6 10.4 13.8 13.2 8.8 10.3 9.4 9.7 9.0 6.3 6.5 9.0 7.2 13.8 10.0 11.2 9.2 14.6 8.1 7.8 11.6 11.3 18.2 11.8 13.2 6.8 5.5 11.1 8.5 7.0 17.7 8.0 10.6 22.8 5.1 8.8 8.1 11.2 9.8 7.6 7.1 10.8 8.8 10.5 23.7 9.1 7.8 5.8 14.1 4.4 7.0 8.5 11.2 13.4 10.5 2.7 5.3 9.4 5.7 6.5 5.0 4.6 6.8 14.8 8.2 7.6 4.1 5.9 5.8 4.3 14.5 6.0 12.9 9.1 7.0 15.8 7.6 4.3 8.1 9.2 4.0 7.8 14.4 5.5 15.0 10.6 0.1 11.4 3.0 15.1 5.4 5.4 10.0 5.7 10.3 10.7 8.9 7.5 5.1 5.9 10.8 11.6 3.2 12.4 7.0 6.7 12.1 7.2 14.6 7.3 3.6 5.8 10.2 16.4 5.7 5.8 2.0 7.5 3.0 4.1 6.6 8.3 5.6 8.5 8.8 11.0 11.3 6.0 15.2 17.1 12.3 0.7 10.9 16.1 6.6 7.6 6.3 10.4 12.5 13.8 13.2 10.0 11.2 11.6 11.3 11.1 11.2 10.8 14.1 11.5 16.0 5.3 8.5 5.7 1.7 3.7 4.0 3.4 15.9 6.5 9.0 40.8 2.8 9.4 5.5 4.2 3.6 3.1 5.3 17.6 6.3 3.3 4.6 7.3 8.9 4.2 1.7 6.8 4.9 1.0 11.2 5.6 4.0 2.5 13.1 7.5 8.5 3.8 13.5 7.8 6.5 4.1 5.4 2.0 2.5 9.3 3.3 5.4 2.8 3.0 16.1 15.5 8.0 11.7 2.6 4.6 12.0 2.6 2.7 6.9 8.0 14.5 15.5 0.0 22.3 14.6 18.9 8.9 3.2 0.9 1.1 6.2 13.1 4.4 1.5 ZNF208 "PMIDP, ZNF95" ENSG00000160321 "Zinc finger protein 208" O43345 19 21932958-22010949 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.4;Late spermatids: 14.1;Oligodendrocytes: 26.3" "Group enriched" "Detected in some" 4 "ovarian cancer: 0.6;testis cancer: 1.9;thyroid cancer: 0.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.3;NTERA-2: 33.1;SuSa: 6.9;U-266/84: 11.2" HPA077100 Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA077100: " "unprognostic (4.06e-3)" "unprognostic (2.90e-1)" "unprognostic (1.09e-1)" "unprognostic (1.75e-1)" "unprognostic (7.46e-2)" "unprognostic (1.66e-1)" "unprognostic (2.87e-1)" "unprognostic (6.23e-2)" "unprognostic (1.64e-2)" "unprognostic (1.73e-1)" "unprognostic (1.29e-2)" "unprognostic (1.66e-1)" "unprognostic (4.94e-2)" "unprognostic (7.21e-3)" "unprognostic (1.70e-1)" "unprognostic (1.47e-2)" "unprognostic (2.73e-3)" 4.2 1.1 4.0 1.9 6.5 1.5 3.4 2.8 4.5 4.0 2.4 4.9 1.4 6.6 4.6 2.2 4.9 3.5 11.4 6.0 7.0 4.6 0.7 1.3 2.8 8.9 7.3 3.4 2.6 13.3 7.1 2.7 8.7 3.5 1.5 2.4 2.8 3.2 0.9 4.0 2.2 6.0 3.0 2.7 1.7 8.6 6.2 0.5 7.9 1.3 1.7 3.2 2.6 6.9 0.4 0.3 0.5 1.1 0.0 0.2 1.5 0.3 0.1 0.2 0.1 1.8 0.6 0.6 0.3 0.3 9.3 0.7 1.2 0.2 0.4 0.2 0.2 0.6 1.5 0.8 0.0 0.4 0.2 1.0 0.3 0.0 0.2 0.7 0.4 0.4 0.5 1.6 0.0 0.5 0.4 0.6 33.1 0.0 1.1 0.2 0.0 1.9 1.1 1.8 0.8 1.6 0.2 0.8 0.3 6.9 0.9 0.8 0.0 0.5 0.3 1.9 0.1 1.0 11.2 0.2 0.1 0.4 0.7 2.4 0.6 0.7 0.8 0.4 0.4 1.3 1.5 0.5 0.3 1.6 0.6 0.9 2.6 1.0 0.3 1.6 1.5 0.3 4.0 6.5 2.8 4.5 6.0 7.0 8.9 7.3 8.7 3.0 6.2 6.9 6.7 0.0 0.0 11.4 4.3 0.0 1.0 0.0 0.6 6.6 4.2 2.5 11.4 0.0 1.3 5.5 0.0 6.8 0.5 0.0 3.9 6.6 15.4 0.2 3.7 3.4 0.0 1.3 11.5 0.2 3.1 5.9 0.5 0.1 0.0 2.7 1.1 0.5 0.7 3.3 1.7 0.0 0.0 0.0 0.7 14.1 1.5 0.2 0.0 9.4 0.0 0.8 1.0 11.1 26.3 0.7 0.0 1.2 0.4 1.2 0.0 2.6 0.0 0.4 0.0 2.5 1.7 8.7 6.2 0.9 0.3 5.3 2.2 0.3 0.0 2.0 ZNF320 "DKFZp686G16228, ZFPL" ENSG00000182986 "Zinc finger protein 320" A2RRD8 19 52860851-52897693 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 105.9;U-266/84: 56.1" "HPA043696, HPA062474" Uncertain Uncertain "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cytoplasmic bodies" "HPA043696: AB_10793951, HPA062474: AB_2732685" "unprognostic (3.33e-2)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (2.25e-1)" "unprognostic (2.92e-2)" "unprognostic (7.12e-2)" "unprognostic (1.47e-4)" "unprognostic (8.90e-2)" "unprognostic (3.71e-3)" "unprognostic (2.75e-3)" "unprognostic (2.50e-1)" "unprognostic (2.01e-3)" "unprognostic (6.41e-3)" "unprognostic (1.32e-1)" "unprognostic (2.76e-1)" "unprognostic (7.65e-2)" "unprognostic (2.61e-3)" 4.9 6.3 4.5 6.6 5.8 5.0 10.4 8.9 5.5 8.9 5.1 9.0 6.9 10.0 9.8 5.1 10.5 7.3 7.2 4.9 4.9 10.7 1.5 5.9 6.7 4.5 3.9 13.4 6.8 12.3 6.5 11.1 4.7 10.3 9.7 13.0 6.3 8.0 7.0 9.1 5.3 7.8 2.5 7.5 7.8 5.3 4.7 6.3 10.8 3.6 6.4 9.5 7.1 7.3 11.2 0.5 16.8 28.1 3.8 6.2 19.8 8.0 7.3 10.5 12.7 6.7 3.8 12.5 10.3 6.9 9.3 3.1 0.1 5.7 7.4 0.1 3.6 12.6 16.6 0.1 7.8 0.8 14.2 10.7 4.8 12.2 2.6 4.8 7.8 5.5 12.9 0.8 7.7 0.0 16.1 9.8 20.4 0.2 9.5 12.0 15.3 14.1 10.2 105.9 13.3 26.4 0.3 7.0 2.9 23.3 10.0 1.3 9.0 4.4 11.0 2.7 12.2 14.1 56.1 9.3 0.3 0.2 9.8 3.2 2.1 1.8 3.2 2.6 2.9 2.2 1.8 2.4 2.5 3.2 3.4 3.5 3.5 7.9 2.4 3.7 2.0 2.5 4.5 5.8 8.9 5.5 4.9 4.9 4.5 3.9 4.7 2.5 4.7 7.3 0.6 3.2 1.7 13.7 2.8 1.9 5.8 3.4 1.2 8.3 0.2 0.1 13.2 14.3 5.9 1.8 10.4 10.5 2.9 9.0 0.0 0.3 6.7 1.9 1.0 4.5 10.7 4.2 10.2 0.0 6.3 5.0 6.1 2.8 1.3 0.6 6.8 0.8 4.3 16.8 10.1 9.0 4.1 3.2 3.9 2.7 4.4 1.6 3.6 3.7 2.4 5.6 9.2 17.6 12.4 0.1 6.3 2.6 0.5 9.4 4.1 0.2 4.4 12.4 0.0 9.2 3.2 5.6 5.8 5.3 4.3 7.7 1.8 0.4 7.3 7.5 ZNF705E ENSG00000214534 "Zinc finger protein 705E" A8MWA4 11 71814045-71821548 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.65e-2)" "unprognostic (1.34e-2)" "unprognostic (5.02e-2)" "unprognostic (3.80e-1)" "unprognostic (7.34e-3)" "unprognostic (8.00e-5)" "unprognostic (6.79e-2)" "unprognostic (1.37e-2)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "unprognostic (5.94e-2)" "unprognostic (2.70e-1)" "unprognostic (5.13e-4)" "unprognostic (9.18e-3)" "unprognostic (1.05e-1)" "unprognostic (8.89e-2)" "unprognostic (2.34e-2)" 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ZNF728 ENSG00000269067 "Zinc finger protein 728" P0DKX0 19 22974883-23003176 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 10.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Distal tubular cells: 3.9;Early spermatids: 2.7;Horizontal cells: 8.4;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 3.6;Spermatocytes: 4.4" "Cancer enriched" "Detected in single" 8 "testis cancer: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "GAMG: 1.7;SuSa: 1.8;U-266/84: 2.9" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.12e-2)" "unprognostic (4.25e-2)" "unprognostic (5.00e-2)" "unprognostic (1.78e-2)" "unprognostic (3.56e-1)" "unprognostic (4.03e-1)" "unprognostic (1.13e-2)" "unprognostic (5.45e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-2)" 1.0 0.1 1.4 0.3 2.4 0.0 0.9 1.1 1.4 0.7 0.1 0.4 0.2 1.1 0.6 0.5 1.4 0.4 1.4 1.6 2.4 0.6 0.1 0.2 0.0 1.9 2.5 2.7 0.1 1.7 0.3 0.2 1.9 0.9 0.2 0.8 0.3 1.0 0.0 0.1 0.1 1.0 0.8 0.5 0.1 10.4 2.5 0.0 2.0 1.0 0.0 0.3 0.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.4 1.1 1.4 1.6 2.4 1.9 2.5 1.9 0.8 2.5 2.2 1.3 0.0 0.0 3.3 0.0 0.0 0.1 0.0 0.0 1.4 0.1 0.8 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 2.7 0.0 0.6 0.4 0.0 0.0 0.2 0.0 0.1 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.9 0.0 0.4 0.0 2.5 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.6 0.5 4.4 2.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0