Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADACL4 ENSG00000204518 "Arylacetamide deacetylase like 4" Q5VUY2 1 12644085-12667076 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.20e-1)" "unprognostic (1.89e-2)" 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 231.6;Distal enterocytes: 265.1;Gastric mucus-secreting cells: 271.7;Hepatocytes: 192.9;Paneth cells: 194.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Cell line enhanced" "Detected in many" "A549: 79.4;CAPAN-2: 60.6;HeLa: 36.9;OE19: 89.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" 3.1 59.1 0.1 3.4 1.8 0.8 4.2 0.2 0.7 2.1 0.0 18.9 12.0 1.1 1.8 7.5 1.0 11.9 0.9 0.3 0.3 8.0 50.4 4.8 1.9 5.9 0.8 0.7 22.6 0.8 0.8 1.1 3.5 5.9 8.7 0.4 7.0 5.5 0.2 7.1 11.9 1.3 1.7 3.4 17.1 1.0 2.5 0.3 5.5 0.0 1.7 6.3 3.6 2.4 5.7 79.4 0.0 0.3 4.4 6.9 0.1 10.4 13.1 0.7 0.7 4.2 60.6 0.0 8.0 20.6 14.5 14.5 0.0 1.0 1.0 0.0 0.0 1.7 36.9 24.2 17.2 0.0 0.0 7.5 5.6 2.9 6.2 8.5 1.4 0.0 0.2 0.0 8.0 18.9 0.0 0.0 0.1 89.7 10.1 0.1 0.0 0.3 33.4 34.2 0.1 0.6 19.2 3.1 0.0 0.1 2.6 0.0 17.3 0.5 3.4 0.2 8.5 0.1 0.0 0.0 8.2 0.0 0.9 0.2 2.3 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.3 6.4 0.1 0.5 5.4 0.1 1.8 0.2 0.7 0.3 0.3 5.9 0.8 3.5 1.7 2.5 2.4 0.7 19.2 5.5 0.0 1.8 9.4 122.2 47.1 42.7 1.6 1.9 6.9 3.1 231.6 19.5 14.7 0.0 0.4 0.0 265.1 5.9 100.1 82.9 5.9 8.8 2.7 23.5 0.0 4.3 106.1 3.7 3.6 271.7 30.5 0.0 3.1 3.9 192.9 26.1 1.7 0.9 96.2 12.2 33.0 11.4 118.6 9.0 31.6 3.6 2.8 8.7 2.9 1.0 0.5 0.5 105.9 194.7 3.0 2.1 104.6 57.2 10.8 2.7 0.3 0.0 1.9 5.6 0.9 0.8 12.7 10.5 1.0 2.6 0.1 111.0 118.4 ABHD11 "PP1226, WBSCR21" ENSG00000106077 "Abhydrolase domain containing 11" Q8NFV4 7 73736094-73738867 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.9;Urothelial cells: 241.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 92.6;SK-BR-3: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024042, HPA049641" Approved Supported Mitochondria NA NA 31000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA024042: AB_1844445, HPA049641: AB_2680838" "unprognostic (4.74e-2)" "unprognostic (8.62e-3)" "unprognostic (1.42e-1)" "unprognostic (2.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.73e-1)" "unprognostic (1.83e-1)" "unprognostic (1.81e-3)" "unprognostic (1.91e-2)" "unprognostic (9.32e-2)" "unprognostic (7.79e-2)" "unprognostic (1.74e-1)" "prognostic favorable (3.66e-7)" "unprognostic (3.61e-3)" "unprognostic (4.44e-2)" "unprognostic (1.02e-1)" "unprognostic (7.29e-2)" 7.5 13.5 9.3 5.6 9.8 4.5 12.2 10.6 11.3 9.3 16.4 31.3 15.9 7.2 5.8 13.6 13.8 8.6 21.6 9.1 9.9 29.4 9.5 9.5 4.0 11.4 11.1 3.9 25.7 12.9 16.4 7.6 11.0 23.2 17.4 3.0 21.3 8.2 11.3 13.3 19.8 3.5 10.4 8.1 9.0 7.2 12.3 3.3 28.1 10.3 5.4 8.5 6.9 10.4 46.9 10.7 7.1 16.4 3.7 5.0 39.7 21.1 8.9 12.7 14.9 13.1 51.4 22.2 6.2 9.0 17.3 20.2 3.2 12.1 8.8 8.2 15.4 10.8 6.7 8.3 6.5 11.8 11.4 4.6 5.0 16.4 7.6 4.6 9.2 7.4 15.1 11.8 12.0 92.6 9.2 14.9 8.3 29.5 39.1 5.0 11.4 41.0 29.7 21.8 18.3 7.6 17.1 113.0 7.1 5.1 36.8 7.8 9.1 10.8 10.2 46.5 22.2 7.3 4.2 14.8 17.3 11.2 20.3 10.2 19.1 19.3 8.2 32.7 6.8 10.1 9.1 8.7 19.4 12.7 8.4 5.9 15.2 14.9 33.5 9.2 6.3 11.9 9.3 9.8 10.6 11.3 9.1 9.9 11.4 11.1 11.0 10.4 12.3 10.4 7.9 44.8 15.7 3.3 10.6 5.5 60.3 39.8 10.2 16.6 43.1 21.7 16.9 54.3 60.7 57.0 4.2 86.3 8.7 156.9 72.4 52.1 1.2 98.9 17.3 9.7 62.6 9.4 5.8 40.8 120.1 9.9 35.7 98.1 15.2 6.3 4.6 8.7 28.0 5.0 4.0 106.8 95.6 11.3 10.5 2.3 9.0 13.7 14.2 4.7 10.4 26.6 14.4 3.0 3.7 38.2 151.7 3.4 10.5 53.1 128.2 55.3 127.6 15.2 0.0 10.3 14.4 6.8 7.1 23.3 6.3 127.7 9.6 22.1 128.9 241.3 ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 315.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 29.5 33.0 55.7 27.4 67.3 26.5 26.9 70.0 64.7 32.1 35.9 37.0 47.0 25.3 133.1 50.0 24.8 33.4 30.5 77.3 58.2 45.5 29.8 32.6 30.8 70.9 64.6 30.6 117.8 55.3 42.1 29.6 73.3 35.5 36.4 30.8 36.9 39.9 13.3 52.4 52.8 23.6 66.0 22.0 55.0 19.2 71.8 23.4 80.8 14.8 41.5 37.2 35.1 96.9 67.2 148.3 41.6 50.9 79.6 47.1 93.3 97.0 84.5 73.7 84.6 90.1 93.0 21.8 53.3 77.0 155.1 116.5 44.4 56.8 62.8 22.7 41.9 33.3 46.8 128.4 59.3 33.3 71.6 58.7 42.0 85.4 44.1 95.7 33.2 37.8 25.8 315.3 72.8 142.5 51.8 31.0 29.4 77.8 96.8 39.2 95.3 195.0 43.4 145.7 46.6 39.7 75.4 198.9 133.8 72.3 67.4 47.6 44.6 98.3 63.0 57.1 54.0 38.8 36.1 33.4 61.8 38.7 57.3 15.8 18.8 17.3 9.9 17.0 7.5 3.8 10.2 13.7 17.9 5.1 8.9 8.9 3.6 15.4 17.7 17.0 10.4 8.6 55.7 67.3 70.0 64.7 77.3 58.2 70.9 64.6 73.3 66.0 71.8 96.9 20.7 6.4 6.5 19.2 13.8 17.7 32.0 9.8 19.4 34.5 19.6 19.7 16.6 30.0 13.7 27.6 10.4 91.6 22.2 97.0 27.4 33.7 53.0 24.9 18.1 17.5 34.0 14.5 37.7 34.3 95.2 22.9 35.2 28.3 10.2 26.9 15.0 19.5 114.1 42.1 46.0 28.9 20.3 37.8 43.8 107.1 16.1 62.4 33.8 42.2 58.7 44.1 23.7 50.8 67.5 22.9 77.7 20.7 39.3 31.6 126.7 24.6 13.1 23.3 26.3 13.8 19.5 19.9 37.7 27.2 18.3 130.8 18.0 19.6 33.3 35.2 ABHD17C FAM108C1 ENSG00000136379 "Abhydrolase domain containing 17C, depalmitoylase" Q6PCB6 15 80679684-80755621 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 65.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 201.4;Intestinal goblet cells: 103.7;Urothelial cells: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 127.1;RT4: 102.6;SK-MEL-30: 119.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048890 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA048890: AB_2680546" "unprognostic (3.60e-1)" "unprognostic (5.07e-2)" "unprognostic (1.58e-1)" "unprognostic (2.19e-2)" "unprognostic (7.51e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (2.59e-2)" "unprognostic (5.08e-3)" "unprognostic (2.87e-1)" "unprognostic (1.23e-3)" "unprognostic (5.75e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" "unprognostic (1.89e-3)" 2.5 4.7 17.6 10.3 17.7 5.9 11.7 14.3 18.4 19.3 13.6 65.3 23.3 6.1 2.1 46.5 10.9 6.3 4.2 19.2 16.3 15.6 5.6 19.5 7.2 16.4 16.2 2.0 7.9 7.0 6.0 4.7 14.5 18.1 56.2 16.8 23.6 3.4 1.8 18.7 30.6 5.5 17.0 8.1 36.0 5.2 18.2 5.6 8.0 2.8 23.0 28.7 21.3 16.2 26.4 24.7 15.7 19.8 5.7 11.6 26.8 24.9 93.0 20.7 20.0 20.6 57.7 8.7 9.9 26.4 14.7 52.7 44.1 23.0 18.5 62.0 25.0 0.1 17.7 22.1 9.9 8.0 12.3 24.9 27.1 15.0 7.4 17.9 22.6 9.1 0.2 10.8 12.1 73.3 0.7 0.8 23.3 127.1 9.2 17.4 13.4 24.5 17.0 102.6 13.9 5.7 19.8 33.7 119.9 6.8 16.8 13.5 7.7 12.8 10.5 14.1 22.4 0.8 0.3 8.6 8.3 71.6 14.3 0.0 0.0 0.0 0.7 0.0 0.5 0.3 0.5 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 17.6 17.7 14.3 18.4 19.2 16.3 16.4 16.2 14.5 17.0 18.2 16.2 2.0 12.8 12.5 32.3 1.4 7.1 13.2 14.3 9.6 4.8 15.7 9.4 5.3 17.2 11.1 7.3 8.4 2.2 2.8 201.4 45.0 6.5 0.3 13.4 7.8 6.9 14.5 0.8 18.4 8.9 5.8 3.1 39.8 35.4 0.0 3.0 6.4 6.0 1.1 10.1 20.1 103.7 10.2 1.3 1.5 0.7 1.2 5.9 8.8 6.5 1.4 4.8 0.0 12.1 3.1 28.1 58.6 0.0 2.4 34.5 46.3 5.6 10.5 22.4 0.0 1.0 2.0 0.7 6.0 19.3 22.7 1.0 2.6 19.6 53.2 86.1 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.7;Paneth cells: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 209.6;RPMI-8226: 233.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 17.1 7.3 13.3 25.2 13.8 17.6 15.7 16.8 21.9 12.6 23.2 63.5 44.1 8.1 9.1 18.1 12.0 20.8 7.5 13.2 14.0 14.5 39.3 15.7 29.8 14.2 15.6 12.5 12.3 16.0 11.4 19.8 16.2 11.1 65.7 5.8 14.5 6.2 14.4 6.3 56.3 9.7 13.2 24.0 35.6 6.3 16.2 21.4 22.9 7.9 25.8 15.3 12.8 15.9 29.0 20.6 19.8 12.7 12.3 8.2 0.1 18.6 7.6 13.1 17.6 21.6 29.1 82.3 33.2 6.2 58.6 93.6 32.5 15.3 18.1 52.1 21.9 9.0 35.7 37.5 18.7 39.6 28.9 7.3 17.7 19.2 8.8 6.5 8.7 28.0 23.4 47.9 11.6 11.7 38.5 43.6 9.7 92.1 47.8 209.6 15.0 233.5 36.4 27.6 16.6 7.5 42.5 37.6 11.2 21.3 11.7 68.9 6.9 12.7 18.2 22.6 29.3 53.1 37.5 84.9 16.1 50.9 29.4 89.3 24.7 29.3 25.3 44.4 19.8 16.2 22.7 24.8 15.2 12.6 18.2 23.2 81.6 18.6 61.8 10.2 44.9 24.3 13.3 13.8 16.8 21.9 13.2 14.0 14.2 15.6 16.2 13.2 16.2 15.9 8.4 9.6 9.3 42.4 22.8 33.4 40.8 21.6 18.2 14.3 12.9 6.2 4.6 40.0 25.4 3.7 47.9 30.6 24.4 187.7 1.9 52.9 4.1 32.6 9.9 9.5 36.4 10.3 27.2 27.5 22.7 10.6 32.1 49.4 11.4 1.2 10.4 31.6 68.5 0.0 30.9 57.9 52.9 31.9 47.2 1.5 7.5 26.4 32.0 33.7 29.6 7.8 26.8 17.1 10.7 51.1 126.6 6.4 45.5 32.0 93.8 8.8 40.8 15.7 13.1 6.8 13.2 4.1 9.7 22.4 15.2 94.3 38.3 5.4 36.8 36.8 ACADVL "ACAD6, LCACD, VLCAD" ENSG00000072778 "Acyl-CoA dehydrogenase very long chain" P49748 17 7217125-7225266 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 850.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019006, HPA020595" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria NA NA 98000 "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Nucleoplasm, Nucleoli" "HPA019006: AB_1844478, HPA020595: AB_1844479" "unprognostic (4.81e-2)" "unprognostic (2.86e-1)" "unprognostic (2.21e-2)" "unprognostic (1.09e-2)" "unprognostic (6.63e-3)" "unprognostic (1.51e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (6.87e-4)" "unprognostic (3.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (4.01e-1)" "unprognostic (2.84e-3)" 197.9 405.2 120.1 78.7 131.0 103.5 142.9 128.4 126.7 110.5 170.6 157.3 306.2 98.5 44.4 181.0 94.0 92.6 576.8 117.8 125.0 215.3 517.4 106.7 52.0 127.5 125.3 80.9 236.5 159.6 189.6 112.0 124.8 133.2 131.6 34.9 158.5 113.9 850.4 135.7 270.6 110.6 118.2 132.2 186.4 75.9 132.0 83.4 159.3 817.1 82.9 137.1 115.3 122.7 193.7 162.5 65.8 92.4 271.2 99.2 135.9 156.5 169.0 136.9 84.5 67.2 155.3 90.4 109.0 260.0 49.7 147.9 43.8 135.5 119.6 295.9 47.1 50.6 120.9 101.1 131.2 49.0 129.5 112.5 122.0 114.7 178.5 212.6 124.8 111.3 73.3 110.2 222.7 65.3 49.6 68.4 34.3 178.4 91.9 70.4 78.3 227.2 305.1 155.0 19.1 47.3 206.8 224.8 110.8 60.6 102.8 74.9 151.5 127.5 101.6 75.9 149.9 104.5 59.1 5.2 230.7 85.7 94.9 24.2 96.1 121.3 39.1 57.8 35.7 25.2 32.5 43.8 99.9 24.6 23.7 29.1 20.2 37.8 39.3 80.4 31.8 79.4 120.1 131.0 128.4 126.7 117.8 125.0 127.5 125.3 124.8 118.2 132.0 122.7 109.9 60.9 81.9 143.3 72.3 87.3 336.0 322.4 91.6 42.0 157.7 104.5 451.4 138.7 206.7 202.3 62.6 482.9 87.7 484.2 185.9 310.8 133.0 87.2 52.7 77.4 179.3 65.2 40.9 77.0 197.8 118.6 406.7 88.5 88.4 121.1 53.6 365.4 182.4 33.7 33.4 251.8 233.9 67.9 94.6 249.9 124.5 101.5 81.8 34.7 274.9 40.7 73.2 23.1 24.5 106.1 388.9 132.8 172.3 369.0 489.8 345.8 144.1 41.3 105.2 88.3 147.4 114.3 47.8 113.8 87.5 663.3 75.5 169.2 316.8 367.5 ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 98.2;skeletal muscle: 163.2;tongue: 48.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 86.2;Erythroid cells: 37.7;Exocrine glandular cells: 39.7;Horizontal cells: 55.5;Paneth cells: 118.3;Proximal enterocytes: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.9;CACO-2: 13.0;K-562: 13.9;Karpas-707: 19.7;U-2 OS: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 990000 "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" 1.4 4.7 20.9 2.2 16.8 7.9 2.0 37.1 32.5 5.0 0.0 7.6 4.9 2.6 0.2 2.3 3.2 1.3 12.5 8.0 98.2 8.8 4.1 4.4 3.5 66.1 54.2 4.6 4.3 4.7 8.3 0.7 72.7 8.1 1.8 5.7 7.1 1.6 163.2 1.3 9.1 0.5 26.2 3.5 2.4 3.9 58.1 3.6 2.3 48.0 1.5 1.4 3.7 10.5 0.0 0.2 0.2 0.2 0.3 0.0 7.9 0.3 0.0 0.1 0.2 13.0 0.1 0.0 0.6 0.0 1.2 0.6 2.0 0.1 0.0 4.6 0.5 0.2 0.1 0.2 0.1 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.0 0.1 13.9 19.7 0.1 4.3 0.0 0.2 1.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.8 1.5 0.1 0.8 0.0 2.9 0.0 0.0 0.2 0.5 6.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.9 16.8 37.1 32.5 8.0 98.2 66.1 54.2 72.7 26.2 58.1 10.5 0.5 0.0 0.0 3.3 0.5 0.8 20.9 0.9 6.2 13.5 2.9 1.1 6.4 5.7 0.4 0.0 0.0 8.2 0.9 86.2 0.0 10.5 0.0 0.5 1.5 2.1 3.5 37.7 4.7 39.7 2.6 3.0 1.5 2.4 0.0 7.4 2.2 0.4 0.8 55.5 9.7 12.0 0.0 0.3 6.6 0.4 0.6 1.7 1.8 1.0 4.6 11.4 0.0 8.5 0.8 20.1 118.3 0.7 1.8 20.4 45.6 1.1 0.1 6.8 0.0 13.5 4.9 4.1 8.0 1.7 1.0 7.1 0.6 1.4 4.6 15.2 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACSF3 ENSG00000176715 "Acyl-CoA synthetase family member 3" Q4G176 16 89088375-89164121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 242.9;U-698: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008322 Supported Nucleoplasm,Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA008322: AB_1845294" "unprognostic (1.94e-1)" "unprognostic (3.35e-1)" "unprognostic (4.66e-2)" "unprognostic (1.56e-2)" "unprognostic (1.14e-1)" "unprognostic (7.87e-2)" "unprognostic (5.68e-2)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.96e-1)" "prognostic favorable (3.76e-5)" "unprognostic (3.36e-2)" "prognostic favorable (5.97e-6)" "unprognostic (2.33e-1)" "unprognostic (5.09e-1)" "unprognostic (3.67e-1)" "unprognostic (2.00e-3)" 8.9 20.5 8.0 15.9 8.2 11.6 9.4 9.9 11.4 9.2 9.6 17.1 30.7 9.6 9.7 10.5 9.5 9.7 9.8 8.0 7.1 11.6 19.2 7.9 21.7 9.1 8.2 8.9 15.6 18.5 7.7 6.1 9.3 8.6 11.4 5.9 13.2 6.5 13.1 10.5 26.4 7.8 7.1 13.3 12.6 7.8 10.6 37.6 9.8 16.5 13.9 10.2 8.7 12.0 12.8 17.8 8.4 14.4 14.5 13.3 19.6 16.5 6.1 16.2 10.4 16.2 20.9 33.2 21.5 14.2 10.5 20.9 8.6 19.4 10.0 12.3 20.6 25.8 16.6 23.8 35.2 8.1 13.3 19.4 22.0 12.4 18.1 18.5 11.7 242.9 36.4 10.1 9.0 32.7 45.6 25.7 9.8 24.8 30.0 53.2 7.2 14.1 15.9 17.2 20.6 15.3 26.6 6.8 26.2 13.5 23.1 28.6 11.6 17.3 12.8 10.2 12.5 11.7 17.3 113.0 15.4 29.8 14.5 7.0 23.0 17.2 22.7 22.8 25.2 29.8 18.5 16.5 21.7 20.6 19.5 17.4 9.0 10.8 21.3 24.6 19.6 17.9 8.0 8.2 9.9 11.4 8.0 7.1 9.1 8.2 9.3 7.1 10.6 12.0 9.2 0.0 11.4 9.4 22.5 3.2 7.6 11.9 4.0 20.2 8.5 7.5 9.1 11.5 15.5 5.5 31.3 11.9 17.5 29.9 15.6 16.1 13.8 10.3 9.3 10.3 16.8 14.3 10.1 10.7 3.8 9.3 17.3 8.1 2.5 44.7 7.9 12.5 18.6 21.9 9.5 19.4 28.5 19.5 14.2 20.4 12.2 14.0 7.2 14.0 18.6 9.3 13.4 9.0 11.2 16.3 20.8 10.1 21.2 8.9 54.7 13.5 10.0 19.0 39.5 11.1 9.7 8.8 8.5 8.2 4.5 7.3 17.0 20.1 31.1 7.4 ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 117.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 137.7;Hepatocytes: 138.9;Intestinal goblet cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.3" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.3;monocytes: 21.8" "Cell line enhanced" "Detected in many" "HBEC3-KT: 132.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved NA NA 16000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" 69.3 23.7 4.0 10.7 9.3 7.5 27.2 6.8 7.8 15.1 6.0 54.6 64.2 13.7 34.3 18.6 22.1 10.7 49.8 3.3 6.4 22.0 46.9 23.2 4.0 12.1 5.9 13.0 14.8 19.6 3.8 17.2 12.7 12.2 32.9 5.3 38.1 16.2 117.3 17.1 46.8 11.3 5.1 8.1 37.7 10.6 7.2 4.0 9.6 99.2 7.0 9.3 11.9 16.3 32.8 11.6 17.1 10.7 69.5 59.1 25.5 14.5 32.4 13.9 21.7 27.3 40.6 0.1 18.6 24.1 50.2 26.0 20.1 132.4 9.5 0.1 7.1 37.2 6.6 18.5 46.2 6.6 28.1 50.3 34.2 24.8 34.5 27.8 27.7 4.2 22.0 7.1 15.8 13.3 2.4 18.8 3.3 27.6 44.1 15.9 20.3 83.4 62.5 9.0 2.9 14.5 24.7 49.1 32.1 21.2 19.6 24.4 23.5 12.3 7.8 12.4 7.9 24.0 19.7 9.1 32.3 9.3 9.1 34.3 21.8 6.6 1.2 13.3 1.2 0.7 3.0 1.3 22.6 1.1 5.3 2.9 12.2 0.7 6.4 4.2 2.0 9.2 4.0 9.3 6.8 7.8 3.3 6.4 12.1 5.9 12.7 5.1 7.2 16.3 8.8 12.8 41.1 17.6 4.2 7.8 9.4 13.5 10.2 6.4 27.6 10.9 82.2 20.0 16.6 11.0 6.2 15.5 3.7 137.7 11.7 20.8 9.0 8.0 8.2 13.5 7.8 29.0 18.5 33.7 11.2 11.4 58.1 13.0 9.5 35.3 13.6 138.9 16.4 8.4 18.2 100.6 18.3 17.9 13.9 7.2 11.5 15.6 14.2 17.8 19.4 9.1 1.0 5.5 86.5 23.4 66.4 4.5 14.6 11.2 70.4 60.5 7.6 4.1 13.1 7.2 9.8 32.1 20.3 12.3 10.9 20.9 5.1 7.8 75.1 13.0 ACTN4 FSGS1 ENSG00000130402 "Actinin alpha 4" O43707 19 38647649-38731589 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 626.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 947.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001873, HPA006035" Supported Approved "Nuclear bodies,Actin filaments,Cytosol" NA NA 71000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Actin filaments" Cytosol "HPA001873: AB_1078096, HPA006035: AB_1078095" "unprognostic (1.03e-1)" "unprognostic (6.34e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-2)" "unprognostic (2.37e-1)" "unprognostic (3.34e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.70e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.99e-1)" "prognostic favorable (5.25e-5)" "unprognostic (6.59e-2)" "unprognostic (1.91e-1)" "unprognostic (6.75e-3)" "unprognostic (6.52e-2)" 176.5 160.8 22.9 63.9 42.0 74.2 151.4 42.9 42.2 165.2 58.5 168.5 128.7 269.4 11.8 232.8 163.2 46.8 89.0 19.5 27.8 166.7 85.0 174.7 37.5 45.9 42.4 102.5 90.6 42.2 80.0 85.7 44.8 115.6 42.2 26.0 148.1 59.0 52.2 183.4 150.3 73.1 30.2 118.1 120.9 23.6 38.1 18.5 105.4 18.8 24.2 150.2 181.3 63.4 364.6 947.0 92.9 48.6 37.7 50.6 237.2 198.7 162.5 178.8 143.9 335.9 265.1 99.0 409.1 260.6 117.4 185.1 57.4 203.8 38.3 238.3 69.5 139.7 356.1 240.4 103.4 101.7 145.2 95.3 63.4 157.5 79.6 146.9 116.4 26.3 165.0 71.8 127.5 221.2 27.2 44.1 78.4 197.8 177.3 89.5 109.4 43.8 174.6 396.3 83.0 49.8 366.3 210.5 94.7 64.0 94.5 78.8 309.7 249.3 138.7 135.3 476.1 44.1 84.5 67.8 231.7 90.6 476.7 7.6 8.1 17.8 13.2 7.7 9.8 3.2 5.7 13.2 7.0 3.0 0.9 4.4 16.9 24.8 6.7 10.8 9.5 10.6 22.9 42.0 42.9 42.2 19.5 27.8 45.9 42.4 44.8 30.2 38.1 63.4 315.2 179.5 120.0 21.5 45.8 234.8 266.4 155.1 153.7 25.6 134.0 148.1 9.2 143.0 119.4 152.6 14.6 123.7 150.7 626.1 19.6 413.5 2.5 272.0 145.7 206.2 162.0 59.3 46.0 419.3 256.7 77.3 219.7 346.4 73.5 75.9 130.6 108.5 72.6 23.5 22.6 365.5 73.2 65.9 103.7 4.5 41.3 75.4 46.2 48.7 162.2 122.4 120.5 35.2 83.6 532.3 425.2 71.5 91.2 322.1 315.5 104.0 122.1 32.3 190.7 97.2 251.0 36.2 23.7 189.3 202.7 168.0 119.4 115.3 280.6 284.7 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951699-51997078 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB026126: , HPA063761: AB_2685115" "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 16.5 10.3 20.7 10.0 20.8 13.5 13.2 13.6 23.4 13.9 9.1 24.6 28.2 8.8 18.0 20.9 15.3 12.2 10.1 21.5 13.3 34.3 29.9 14.7 6.4 12.5 13.9 9.4 40.7 52.7 14.7 11.1 13.1 14.0 24.4 17.4 32.8 15.3 13.1 45.6 26.1 8.1 9.5 8.8 24.9 15.7 16.1 7.6 11.4 8.8 7.4 12.6 18.8 18.3 11.4 24.3 18.6 10.3 20.9 16.2 10.5 12.6 14.2 13.1 9.9 49.5 17.1 5.0 17.2 13.8 14.6 19.6 17.8 15.2 13.5 7.3 21.0 12.3 5.9 15.6 23.8 19.9 43.8 32.0 19.4 14.8 18.6 13.9 18.7 17.7 13.3 14.9 11.8 23.2 19.1 17.2 18.0 24.0 8.5 10.2 14.4 6.4 37.2 17.0 23.5 19.5 13.6 19.2 9.0 13.1 21.1 12.8 12.0 9.0 13.6 10.2 6.1 9.0 6.8 6.7 9.7 9.4 11.8 2.5 1.2 3.9 0.3 1.8 0.5 0.0 0.3 0.3 0.7 0.2 0.8 0.4 1.0 0.0 2.2 0.3 0.5 0.3 20.7 20.8 13.6 23.4 21.5 13.3 12.5 13.9 13.1 9.5 16.1 18.3 8.0 3.2 13.4 8.1 2.9 18.6 10.1 9.2 23.3 45.3 11.3 8.6 5.9 17.2 12.0 25.8 29.2 0.7 2.0 49.7 3.9 17.7 2.9 12.3 8.1 10.9 24.6 0.8 34.8 14.4 0.8 12.6 19.9 9.0 11.4 9.4 17.9 24.4 4.0 37.0 30.2 28.7 2.0 16.7 5.3 8.4 9.9 10.0 7.2 9.4 10.1 8.8 1.0 21.6 11.3 13.3 22.1 9.4 2.3 15.1 31.8 17.0 15.8 24.5 6.6 17.5 12.2 3.8 16.5 17.7 25.3 0.5 4.6 5.6 24.7 15.5 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 96.3" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Distal enterocytes: 182.7;Endothelial cells: 84.7;Fibroblasts: 56.0;Hepatic stellate cells: 60.3;Paneth cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cell line enhanced" "Detected in some" "ASC diff: 61.4;ASC TERT1: 42.1;EFO-21: 61.0;HUVEC TERT2: 200.0;TIME: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 49.2 12.1 17.1 20.1 14.5 0.6 38.4 15.5 14.9 35.9 10.5 39.2 10.2 28.1 4.3 11.4 32.7 14.3 38.5 13.3 14.6 29.8 3.3 96.3 15.1 17.8 16.7 4.8 12.0 23.6 6.2 83.8 18.7 17.7 28.4 0.7 11.8 13.3 18.2 18.5 28.5 16.2 14.0 29.2 19.1 1.7 22.0 4.6 29.2 15.7 6.1 25.1 25.6 15.0 0.0 0.7 0.4 0.0 61.4 42.1 0.1 3.0 5.6 0.1 0.3 0.3 0.4 0.1 61.0 24.0 0.2 0.0 0.0 0.0 0.1 0.1 2.1 1.4 0.0 0.0 9.0 0.0 1.3 16.8 0.1 0.4 0.0 0.0 200.0 0.0 0.2 0.1 1.1 0.5 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.1 0.4 0.0 4.1 161.2 0.0 0.4 0.7 0.0 0.0 0.1 0.2 0.3 0.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 17.1 14.5 15.5 14.9 13.3 14.6 17.8 16.7 18.7 14.0 22.0 15.0 107.3 3.2 7.9 0.0 0.6 5.2 0.3 0.0 0.6 0.4 1.0 1.3 4.0 0.0 1.3 0.0 0.0 0.6 0.3 182.7 0.0 4.0 0.0 1.4 19.9 84.7 5.4 0.0 0.1 1.4 36.9 56.0 0.5 0.7 0.0 0.0 60.3 0.1 12.0 0.0 0.0 26.4 0.0 30.9 12.4 1.2 11.8 7.8 5.4 25.3 9.9 2.0 0.0 1.0 0.1 0.0 74.7 3.4 0.1 0.6 4.5 0.0 2.8 0.4 39.5 32.9 18.2 0.1 0.8 0.6 5.4 2.6 1.2 0.6 49.3 1.0 ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.5;Extravillous trophoblasts: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Cell line enhanced" "Detected in many" "PC-3: 329.5;RPMI-8226: 361.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" 70.1 18.5 12.5 21.4 16.0 34.1 64.7 16.9 13.9 40.3 7.1 38.3 16.4 42.5 7.6 79.1 41.5 21.6 63.1 10.5 13.8 32.4 15.1 50.0 10.0 20.2 15.1 25.5 25.5 30.0 14.1 39.1 16.8 40.0 23.8 3.4 45.3 16.7 22.7 107.9 31.3 38.6 17.3 28.8 44.2 4.9 17.1 7.3 31.6 32.4 13.6 38.9 57.3 18.0 112.0 35.0 7.0 153.2 54.9 45.6 66.3 48.2 60.9 60.1 40.5 25.9 63.3 30.9 210.7 63.5 26.7 135.9 34.5 147.9 15.8 14.3 44.9 7.6 63.1 25.3 95.5 63.4 7.9 48.7 153.8 60.5 86.6 82.6 274.7 9.3 11.9 124.8 45.2 64.7 0.5 47.1 21.6 193.4 329.5 10.0 20.5 361.8 43.7 29.7 20.8 44.7 105.2 131.2 41.8 10.7 194.8 38.9 205.1 58.6 24.6 58.9 54.1 13.9 11.7 13.7 42.7 47.6 65.4 0.0 39.1 0.8 9.5 26.5 6.5 2.0 4.7 5.6 64.0 2.1 2.0 2.5 1.4 1.6 6.2 5.3 8.9 22.8 12.5 16.0 16.9 13.9 10.5 13.8 20.2 15.1 16.8 17.3 17.1 18.0 164.5 3.2 6.7 8.8 6.6 48.9 30.4 81.6 47.8 9.7 34.6 20.7 11.5 35.8 38.3 9.2 29.2 13.0 8.1 100.4 0.0 33.4 1.7 13.3 9.2 120.8 12.7 4.6 8.1 25.5 172.4 19.8 85.6 15.4 1.3 8.5 62.2 19.9 31.7 6.7 9.8 80.7 18.3 65.0 43.6 1.3 17.4 27.2 14.2 15.9 28.8 8.8 13.4 9.0 16.8 42.1 50.9 18.0 8.0 55.2 47.4 2.6 22.9 17.0 13.1 15.7 14.5 0.8 6.4 91.2 57.1 17.8 8.6 2.7 76.9 40.0 ADAP1 "CENTA1, GCS1L" ENSG00000105963 "ArfGAP with dual PH domains 1" O75689 7 897900-955407 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.9;intestine: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 97.7;Intestinal goblet cells: 42.5;Oligodendrocytes: 43.6;Paneth cells: 64.4;Proximal enterocytes: 48.5;Undifferentiated cells: 50.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 15.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 108.1;CAPAN-2: 74.1;HMC-1: 71.0;OE19: 191.5;THP-1: 122.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007033, HPA012049" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA007033: AB_1846529, HPA012049: AB_1846527" "unprognostic (2.45e-1)" "unprognostic (7.15e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (4.41e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (3.06e-1)" "unprognostic (9.10e-3)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-1)" "prognostic favorable (4.13e-5)" "unprognostic (5.88e-2)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-2)" 4.9 3.8 51.2 11.2 55.8 9.8 3.4 57.3 73.6 4.1 11.2 43.2 19.7 6.0 0.6 9.0 8.8 6.0 8.1 59.4 42.9 22.3 3.6 10.4 3.8 63.5 63.1 1.5 13.3 6.1 4.7 2.7 56.9 6.6 22.8 1.6 4.6 2.9 0.7 3.9 26.8 8.3 48.7 17.2 19.6 1.1 55.4 0.9 7.6 0.5 2.1 8.9 3.8 85.9 108.1 4.0 0.1 3.7 1.4 0.2 1.1 3.6 0.1 0.7 0.1 43.1 74.1 0.2 10.3 0.5 0.2 44.5 5.9 8.1 0.5 0.6 4.7 0.0 6.0 25.4 1.7 0.7 71.0 1.8 21.4 0.2 0.0 0.1 0.0 3.1 0.4 0.0 0.0 33.2 0.1 30.1 3.2 191.5 0.0 14.4 0.2 0.4 4.7 25.0 3.1 1.0 3.3 1.3 0.5 0.4 25.9 122.6 0.6 0.8 2.8 0.1 0.3 0.0 0.2 0.0 0.2 22.3 3.3 1.0 6.5 3.3 6.0 7.3 2.8 1.1 1.6 5.5 5.1 0.9 0.5 2.6 3.1 1.6 11.7 0.3 0.8 4.0 51.2 55.8 57.3 73.6 59.4 42.9 63.5 63.1 56.9 48.7 55.4 85.9 0.4 0.0 10.3 2.9 3.6 1.0 2.9 3.3 2.8 4.7 2.5 1.5 8.5 7.2 2.9 7.3 0.0 0.3 19.4 97.7 9.8 3.9 0.2 8.6 0.9 0.5 16.2 0.0 13.2 4.6 0.9 1.5 17.9 7.6 7.0 1.3 0.0 0.6 12.2 0.0 12.6 42.5 4.1 23.0 15.7 0.4 0.0 22.1 10.6 2.8 13.2 1.3 15.5 3.0 43.6 17.5 64.4 0.0 2.6 3.0 48.5 7.1 8.2 1.1 0.0 0.1 1.9 0.3 1.2 1.1 1.3 0.7 9.0 0.0 50.6 5.5 ADCY6 AC6 ENSG00000174233 "Adenylate cyclase 6" O43306 12 48766194-48789089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018365 Approved Approved "Golgi apparatus" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB018365: AB_2257941" "unprognostic (1.18e-2)" "unprognostic (2.20e-2)" "unprognostic (6.89e-2)" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (3.68e-2)" "prognostic unfavorable (8.23e-4)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-3)" "unprognostic (5.10e-3)" "unprognostic (1.09e-1)" "unprognostic (3.09e-1)" "unprognostic (2.48e-2)" 43.2 15.0 8.9 6.1 7.9 1.3 23.7 5.0 9.2 19.3 10.3 26.3 18.7 20.7 19.0 10.3 17.1 13.9 57.2 8.0 11.2 21.1 9.6 13.5 3.9 5.5 5.4 22.3 22.3 20.7 14.6 14.5 6.6 16.3 20.3 5.7 33.5 16.5 12.1 15.3 21.4 13.6 1.9 4.8 25.1 4.0 14.4 2.8 17.9 12.7 3.2 12.3 12.8 6.4 14.0 25.9 30.2 18.9 32.0 15.9 32.0 16.7 17.1 19.8 13.8 45.7 45.3 0.0 37.2 15.3 8.2 10.9 9.2 11.6 7.9 0.1 13.4 12.5 37.8 8.4 17.6 0.0 10.1 20.0 13.6 17.1 6.5 37.9 18.7 0.8 1.7 4.5 15.6 23.1 0.0 0.5 10.3 21.6 12.3 4.6 11.4 7.7 23.4 41.5 4.5 18.4 17.2 68.0 15.2 13.3 53.3 3.5 21.1 18.3 13.1 9.7 7.4 7.0 3.7 0.4 16.9 0.0 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 7.9 5.0 9.2 8.0 11.2 5.5 5.4 6.6 1.9 14.4 6.4 11.6 0.0 6.4 18.3 0.6 2.7 3.3 7.5 4.0 10.1 22.7 15.0 8.2 7.2 9.8 18.4 20.9 7.4 0.4 38.8 0.0 5.8 0.8 6.8 8.0 8.1 8.4 0.0 17.5 4.0 2.7 7.6 14.3 11.3 1.3 14.6 5.0 7.7 2.5 10.1 18.8 24.9 8.2 0.6 2.8 1.1 11.5 0.7 7.2 7.5 0.6 3.4 0.0 15.1 7.0 9.5 30.3 9.4 0.3 6.3 26.0 2.8 5.8 9.3 19.7 9.5 26.6 1.9 1.7 3.6 2.0 5.1 0.8 13.9 23.7 9.3 AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" 26.1 25.9 16.4 21.9 17.0 32.4 29.2 18.2 19.0 24.1 30.8 60.8 79.9 22.1 17.5 41.5 23.8 18.3 88.0 17.0 18.7 62.7 51.0 21.8 23.7 17.7 16.6 24.1 41.1 76.0 18.6 23.5 18.8 24.6 54.1 20.3 30.8 24.4 145.4 29.8 58.7 25.4 15.8 18.5 39.1 18.5 19.0 24.3 39.2 155.8 31.0 30.9 19.6 17.6 56.5 56.6 39.7 44.8 45.2 48.6 52.7 61.9 61.1 86.6 63.1 88.1 34.1 161.3 66.3 56.6 76.8 55.6 101.4 71.3 70.3 38.1 43.5 48.5 59.3 83.5 61.1 185.0 69.8 54.3 76.3 82.1 107.7 47.8 64.0 57.0 111.3 92.8 43.6 89.0 66.7 58.5 55.3 277.4 41.9 74.0 125.1 135.2 74.9 123.6 73.7 51.3 97.0 103.8 90.0 50.5 47.8 84.5 49.0 102.4 88.6 98.7 81.7 64.7 80.7 104.1 56.2 71.4 48.0 3.8 16.5 12.4 11.6 17.6 13.9 14.0 13.8 17.9 21.8 10.3 17.2 20.2 1.1 28.4 16.2 11.5 9.5 13.4 16.4 17.0 18.2 19.0 17.0 18.7 17.7 16.6 18.8 15.8 19.0 17.6 24.3 41.7 49.2 23.2 36.6 22.2 45.3 21.5 42.7 50.2 36.5 36.2 74.9 50.1 28.1 35.0 50.1 58.5 29.1 85.2 72.4 39.5 5.5 37.8 52.3 27.7 39.1 61.0 21.1 37.4 37.9 31.2 53.5 46.1 14.5 41.3 21.8 85.6 37.0 30.3 26.8 82.6 18.3 32.6 14.4 5.5 32.9 34.2 23.2 12.2 27.6 26.9 40.2 14.1 17.7 47.8 43.1 30.1 38.8 43.1 88.7 100.0 22.1 58.3 26.3 53.6 26.9 50.9 65.0 75.8 31.3 92.8 28.4 60.8 94.9 38.2 AHCYL2 "IRBIT2, KIAA0828, long-IRBIT" ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225023-129430211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 488.0;intestine: 177.4" "Cell type enhanced" "Detected in all" "Astrocytes: 567.4;Distal enterocytes: 334.0;Excitatory neurons: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in all" 8 "HDLM-2: 235.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053128 Uncertain Approved Nucleoplasm,Cytosol NA NA 500000 "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA053128: AB_2682050" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (8.52e-3)" "unprognostic (1.71e-3)" "unprognostic (7.44e-3)" "prognostic favorable (4.17e-4)" "unprognostic (8.85e-2)" "unprognostic (1.43e-1)" "unprognostic (3.35e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-1)" "unprognostic (6.79e-3)" "prognostic favorable (1.08e-7)" "unprognostic (4.70e-3)" "unprognostic (2.46e-1)" "unprognostic (7.21e-2)" "unprognostic (2.62e-1)" 7.1 10.2 25.4 15.6 35.9 3.2 8.4 27.2 34.4 10.6 488.0 157.4 57.8 9.1 7.2 9.6 7.4 55.8 4.6 47.3 32.5 28.5 7.7 65.8 10.8 30.3 28.1 11.4 13.7 19.2 21.3 12.1 22.5 9.3 177.4 57.8 30.6 7.0 37.3 24.3 38.6 11.8 27.8 7.0 41.9 10.5 39.0 9.4 42.6 27.7 9.4 16.1 7.6 25.2 8.7 13.5 25.4 15.3 6.8 9.9 5.4 6.8 9.4 7.5 6.6 7.9 5.7 5.3 6.9 7.4 15.9 6.0 12.8 10.7 8.3 235.7 16.0 12.4 14.5 6.4 4.0 9.3 15.4 9.1 13.5 6.0 9.1 12.7 15.1 10.1 5.8 28.7 9.9 8.2 13.7 12.1 12.7 8.6 9.5 9.0 6.9 14.4 15.0 11.5 11.6 7.3 15.5 6.5 9.3 21.0 6.1 6.6 8.6 6.4 3.6 16.9 7.2 12.0 14.6 7.2 16.4 9.8 9.9 0.1 0.4 0.7 0.3 0.9 0.4 0.3 0.5 0.2 0.4 0.1 0.4 0.1 0.1 1.3 0.4 0.1 1.8 0.2 25.4 35.9 27.2 34.4 47.3 32.5 30.3 28.1 22.5 27.8 39.0 25.2 4.7 60.9 98.6 567.4 9.3 15.6 5.1 7.2 31.3 10.8 4.8 4.3 7.3 18.6 16.4 5.5 6.2 12.5 2.2 334.0 11.7 4.5 61.7 5.9 5.3 5.2 9.1 3.4 131.2 5.3 2.9 3.6 30.1 8.7 5.7 6.0 5.7 6.0 4.7 5.0 115.5 32.9 6.1 10.0 6.1 30.6 4.1 7.3 24.9 99.3 7.7 91.0 2.1 127.2 77.5 6.2 71.8 6.8 7.4 6.2 27.0 17.1 8.7 5.9 6.6 5.1 4.3 5.1 2.3 17.8 9.8 15.2 7.3 8.3 46.1 15.1 AIFM2 "AMID, FLJ14497, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 173.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cytosol" "HPA028961: AB_2672844, HPA042309: AB_10796575, HPA075576: " "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (4.29e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.26e-3)" "unprognostic (2.57e-2)" "unprognostic (7.95e-3)" "unprognostic (2.80e-1)" "unprognostic (5.31e-2)" "unprognostic (8.90e-2)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.49e-1)" "unprognostic (4.59e-3)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.92e-4)" 39.6 13.5 7.5 6.3 8.1 1.9 31.2 7.3 8.0 6.9 8.6 12.9 9.3 7.8 9.0 13.3 6.8 5.0 17.0 6.9 7.7 10.4 21.9 9.3 5.1 8.2 7.3 7.9 5.0 3.2 5.6 4.1 6.9 9.9 7.1 2.4 7.6 7.7 9.8 5.6 11.5 5.0 6.2 7.7 9.9 3.9 8.3 2.4 14.6 7.3 3.6 12.0 6.3 6.5 26.5 45.2 1.1 11.3 26.2 9.8 0.3 10.4 25.5 21.0 23.6 35.3 49.8 3.8 25.8 14.5 27.5 27.9 12.7 3.8 5.9 50.8 1.9 0.2 27.3 173.3 56.1 0.3 6.4 13.3 8.4 33.8 7.2 13.2 9.5 1.7 20.5 21.9 11.0 33.5 1.2 1.3 4.5 21.2 14.6 0.8 4.2 12.4 11.4 19.2 3.6 0.8 19.1 16.6 29.8 1.8 0.7 7.2 12.0 0.5 25.3 15.6 30.8 16.2 32.7 7.3 14.0 0.9 13.9 1.0 0.5 0.5 1.8 0.5 1.5 1.7 0.6 1.5 0.4 1.5 0.8 1.3 0.5 4.0 0.5 0.2 1.3 0.7 7.5 8.1 7.3 8.0 6.9 7.7 8.2 7.3 6.9 6.2 8.3 6.5 11.6 6.4 14.1 7.2 5.0 2.3 15.0 8.4 2.8 5.7 5.5 4.7 13.8 8.6 10.5 18.4 0.0 13.9 1.4 53.1 3.9 40.7 24.1 6.0 7.7 4.8 12.0 7.0 8.2 21.9 3.0 11.2 14.3 6.2 11.4 22.3 1.8 25.0 10.2 1.7 5.2 7.1 14.2 3.3 3.3 47.0 5.3 6.7 8.8 4.7 34.4 4.8 1.0 5.5 3.5 40.8 22.7 4.5 17.0 14.6 28.7 22.6 9.5 2.1 19.7 11.8 12.8 6.2 3.9 5.1 1.4 18.6 3.8 8.8 13.7 20.4 AIFM3 "AIFL, FLJ30473" ENSG00000183773 "Apoptosis inducing factor mitochondria associated 3" Q96NN9 22 20965108-20981360 "Predicted intracellular proteins" "Apoptosis, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 70.4;choroid plexus: 136.0" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Distal enterocytes: 76.5;Intestinal goblet cells: 31.3;Muller glia cells: 25.3;Paneth cells: 27.5;Undifferentiated cells: 37.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 1.1;intermediate monocyte: 3.0;myeloid DC: 1.9;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 24 "dendritic cells: 1.9;monocytes: 3.0" "Cell line enhanced" "Detected in some" "Hep G2: 7.6;HMC-1: 10.8;T-47d: 5.3;THP-1: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001271 Supported Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA001271: AB_1078114" "unprognostic (1.39e-1)" "unprognostic (1.97e-1)" "unprognostic (7.49e-2)" "unprognostic (9.99e-2)" "unprognostic (6.79e-2)" "unprognostic (2.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.73e-3)" "unprognostic (3.28e-1)" "unprognostic (1.56e-1)" "unprognostic (4.13e-3)" "unprognostic (5.13e-2)" "unprognostic (7.99e-2)" "unprognostic (6.78e-2)" "unprognostic (1.47e-1)" "unprognostic (3.37e-1)" "prognostic favorable (7.13e-5)" 0.5 0.4 41.5 3.1 36.8 3.7 0.4 39.6 52.9 0.3 136.0 24.8 2.5 0.4 0.0 0.4 0.5 0.6 0.3 29.9 31.4 0.8 0.3 1.1 0.6 46.2 43.7 0.3 0.4 0.5 4.4 0.4 43.2 1.0 8.4 1.8 1.0 0.7 0.1 0.1 1.9 0.8 38.0 2.1 0.5 0.6 70.4 0.1 0.3 0.0 0.0 1.2 0.3 24.9 1.0 1.7 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.2 0.0 1.9 0.0 7.6 0.2 0.0 10.8 0.5 0.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.3 0.0 1.3 1.4 0.9 0.8 0.1 0.0 0.1 5.3 7.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 3.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.5 41.5 36.8 39.6 52.9 29.9 31.4 46.2 43.7 43.2 38.0 70.4 24.9 1.0 0.0 1.5 92.1 1.0 0.6 1.9 1.7 0.6 14.5 3.1 2.4 2.9 0.0 1.4 1.8 6.2 1.0 0.0 76.5 11.7 0.7 0.0 1.7 0.4 0.5 10.3 0.0 12.5 0.6 0.7 0.6 1.5 1.4 1.3 0.5 1.4 2.4 3.6 0.0 8.1 31.3 2.0 3.2 1.9 0.1 0.0 2.5 0.0 4.7 3.2 25.3 0.0 2.5 1.6 0.5 27.5 0.0 0.3 2.2 4.8 8.1 1.9 3.7 0.0 0.2 1.2 0.4 1.9 0.7 0.9 0.8 0.2 0.3 37.9 2.8 AKT1S1 "Lobe, MGC2865, PRAS40" ENSG00000204673 "AKT1 substrate 1" Q96B36 19 49869033-49878459 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 130.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021903, HPA043590, HPA064427" Uncertain Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB021903: , HPA043590: AB_2678569, HPA064427: AB_2685261" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (2.64e-1)" "unprognostic (2.21e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.41e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-1)" "prognostic favorable (6.60e-4)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.34e-6)" "unprognostic (3.20e-2)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (3.65e-1)" 39.0 54.0 35.6 14.2 37.9 14.3 34.9 37.2 41.0 33.1 28.6 40.3 21.8 39.1 14.3 53.2 32.6 12.4 47.1 34.7 36.6 36.2 65.9 25.6 8.7 40.5 41.4 33.1 39.2 24.4 34.2 16.7 40.5 35.0 14.1 6.6 32.8 20.0 118.3 54.0 29.3 17.6 33.9 24.6 40.5 24.0 39.5 8.2 31.4 45.4 9.7 38.5 33.2 39.4 70.9 83.8 24.1 56.0 50.2 53.4 42.5 62.2 69.4 57.4 49.4 45.7 46.0 14.1 31.1 70.6 43.5 47.9 41.9 70.5 33.5 32.2 116.6 17.0 48.2 43.5 44.6 14.9 26.8 65.9 64.0 62.3 70.2 43.0 53.9 16.8 57.0 18.2 52.5 49.5 14.0 36.7 63.0 85.7 120.9 17.1 33.8 43.2 57.9 49.3 56.2 65.4 53.2 93.7 39.9 28.1 49.1 28.9 52.5 118.1 61.7 34.2 62.1 26.4 69.8 15.2 68.4 27.2 57.5 0.1 1.1 0.9 0.7 1.4 0.4 0.4 0.5 0.7 0.8 0.7 0.4 0.7 1.7 0.7 1.6 1.2 1.0 0.6 35.6 37.9 37.2 41.0 34.7 36.6 40.5 41.4 40.5 33.9 39.5 39.4 20.7 0.0 3.3 7.2 15.1 14.7 22.9 33.8 18.8 12.6 31.2 22.6 6.2 27.1 15.5 11.0 2.1 64.0 10.7 56.1 45.0 36.8 24.8 18.2 22.9 20.6 30.0 42.5 4.1 40.2 52.3 23.5 32.1 25.3 4.5 18.6 17.9 42.8 31.1 10.1 4.9 38.8 30.5 20.7 22.8 10.8 23.9 16.6 12.4 4.7 26.9 32.9 15.5 2.5 8.1 34.5 32.9 28.6 17.1 43.3 57.1 55.8 7.2 11.7 26.3 23.7 25.3 12.3 19.3 32.1 20.0 130.0 9.4 26.5 38.1 31.3 AMIGO3 ENSG00000176020 "Adhesion molecule with Ig like domain 3" Q86WK7 3 49716829-49719684 "Metabolic proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Enteroendocrine cells: 1.2;Microglial cells: 1.0;NK-cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 11.0" "Lineage enriched" "Detected in many" 10 "dendritic cells: 11.0" "Cell line enhanced" "Detected in many" "CACO-2: 3.4;HeLa: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.33e-2)" "unprognostic (5.15e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-1)" "unprognostic (2.46e-2)" "unprognostic (4.83e-3)" "unprognostic (3.92e-3)" "unprognostic (3.75e-3)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (7.56e-2)" "unprognostic (7.85e-3)" "unprognostic (3.10e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (2.84e-1)" "unprognostic (3.58e-3)" 0.6 0.8 0.5 0.2 0.4 1.5 0.5 1.4 0.8 0.7 0.1 0.5 0.4 0.7 0.5 1.0 0.8 0.2 0.9 0.3 0.7 0.6 1.9 0.9 0.5 1.0 0.3 1.0 1.6 0.0 3.1 0.1 0.3 1.1 0.0 0.1 0.9 0.3 3.4 3.0 0.8 0.0 0.0 1.1 1.0 1.7 0.4 0.3 0.9 0.0 0.1 0.5 0.6 0.5 0.4 0.4 0.3 0.6 1.9 0.2 1.3 0.3 0.0 0.2 0.1 3.4 0.5 0.0 0.4 0.7 0.1 1.8 0.0 0.2 0.0 1.9 1.0 0.0 4.2 2.2 0.0 1.0 2.7 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.6 0.6 0.0 1.7 1.6 1.7 0.4 0.5 0.5 0.4 0.6 0.4 0.0 1.9 1.5 2.5 1.0 0.2 0.5 0.0 0.2 0.5 1.1 0.3 1.8 1.2 0.3 2.2 1.4 0.5 0.0 1.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.2 0.9 0.1 0.1 0.3 0.6 0.0 1.0 0.0 11.0 0.5 0.3 0.5 0.4 1.4 0.8 0.3 0.7 1.0 0.3 0.3 0.0 0.4 0.5 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 AMT "GCST, NKH" ENSG00000145020 Aminomethyltransferase P48728 3 49416778-49422685 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 42.4;Proximal enterocytes: 33.3;Undifferentiated cells: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 17.1;Hep G2: 47.5;NTERA-2: 8.0;SH-SY5Y: 14.9;SuSa: 9.0" HPA005566 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA005566: AB_1844811" "unprognostic (2.10e-2)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (9.14e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (2.17e-3)" "unprognostic (1.94e-1)" "unprognostic (3.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.90e-8)" "unprognostic (4.40e-1)" "unprognostic (1.91e-1)" "unprognostic (3.60e-1)" "unprognostic (1.98e-3)" 4.7 12.8 9.8 1.2 10.3 8.8 5.6 10.7 11.7 11.8 13.1 12.2 13.8 6.8 8.2 3.5 10.1 5.8 21.6 9.4 9.6 23.2 49.1 5.4 2.1 9.8 10.2 12.5 19.5 14.2 11.9 2.3 9.8 11.3 11.8 6.5 10.6 8.5 3.1 4.8 12.1 3.7 9.9 6.3 11.1 3.0 10.0 3.8 5.8 4.2 1.5 8.0 6.4 9.9 0.1 0.7 1.4 0.4 0.6 0.0 17.1 0.0 0.4 0.1 0.3 0.5 0.6 0.0 0.2 0.4 0.0 0.3 0.1 0.7 0.1 0.3 0.0 0.0 0.5 47.5 1.8 0.0 0.0 0.6 1.8 0.0 0.7 1.3 0.6 0.2 0.0 0.0 0.2 0.4 0.1 0.1 8.0 0.0 0.2 0.0 0.5 1.0 0.8 0.4 0.0 14.9 0.2 0.0 1.1 9.0 0.1 0.3 0.6 0.1 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 3.2 0.0 1.7 0.0 0.5 0.0 0.0 4.2 0.2 1.2 0.9 0.1 7.9 0.5 0.3 0.0 1.3 9.8 10.3 10.7 11.7 9.4 9.6 9.8 10.2 9.8 9.9 10.0 9.9 1.2 3.2 9.2 11.4 3.6 2.8 12.1 3.1 3.4 17.4 1.2 1.3 21.8 14.3 6.3 0.0 20.9 25.6 1.4 13.8 0.0 0.8 2.5 0.7 1.6 3.2 12.7 8.8 8.7 0.7 8.8 4.5 15.8 1.0 7.6 2.0 3.9 42.4 5.0 8.4 8.5 18.4 2.0 3.8 2.9 1.6 10.5 2.6 5.4 7.5 1.8 26.0 7.2 6.0 6.6 0.6 18.9 6.4 1.1 6.7 33.3 1.1 6.6 19.3 6.6 5.2 3.1 1.9 0.3 2.2 2.7 10.3 3.8 1.0 31.6 10.9 ANKRD22 MGC22805 ENSG00000152766 "Ankyrin repeat domain 22" Q5VYY1 10 88819896-88851844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.8;skin 1: 30.9;stomach 1: 46.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 37.2;Distal enterocytes: 38.2;Gastric mucus-secreting cells: 49.5;Paneth cells: 51.5;Squamous epithelial cells: 35.8;Suprabasal keratinocytes: 102.9;Urothelial cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 6.4" "Group enriched" "Detected in many" 14 "granulocytes: 6.4;monocytes: 3.1" "Cell line enhanced" "Detected in some" "A-431: 8.6;CAPAN-2: 26.1;HL-60: 9.4;NB-4: 8.7;OE19: 20.9;RT4: 16.4;T-47d: 12.2;U-937: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA012922 Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA012922: AB_1844838" "unprognostic (1.86e-1)" "unprognostic (1.48e-3)" "unprognostic (9.73e-3)" "prognostic favorable (8.73e-6)" "unprognostic (1.18e-1)" "unprognostic (2.81e-2)" "unprognostic (2.39e-2)" "unprognostic (1.50e-1)" "unprognostic (4.57e-2)" "unprognostic (7.21e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (1.09e-3)" "unprognostic (1.05e-2)" "unprognostic (4.87e-3)" "unprognostic (4.17e-2)" "unprognostic (3.18e-3)" "unprognostic (1.01e-3)" 0.2 0.3 0.6 9.5 0.7 5.4 2.6 0.5 0.9 7.6 0.4 7.2 2.7 0.2 0.3 33.8 0.3 3.2 0.1 0.5 0.7 4.7 2.0 1.5 4.2 1.3 0.8 0.3 12.9 0.8 0.3 0.2 1.1 2.5 7.1 0.1 4.9 0.1 0.1 30.9 2.1 1.6 0.6 6.4 46.3 0.1 0.7 5.5 0.1 0.0 7.8 4.8 13.9 0.9 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 0.0 0.0 6.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.4 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.6 8.7 0.0 20.9 0.1 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 1.3 0.0 0.0 12.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 7.9 0.0 0.0 2.1 1.1 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 6.4 0.2 0.6 0.2 0.0 0.6 0.6 0.7 0.5 0.9 0.5 0.7 1.3 0.8 1.1 0.6 0.7 0.9 0.0 0.0 3.7 0.0 1.0 37.2 18.6 7.6 1.8 0.0 1.5 0.9 0.2 5.7 4.5 7.3 0.0 0.0 0.0 38.2 0.0 3.2 0.0 0.9 0.5 0.3 1.8 0.4 0.0 5.9 0.0 0.6 49.5 4.8 0.0 0.0 0.0 0.6 2.2 0.0 0.0 14.9 16.2 9.3 3.1 0.2 0.3 8.5 1.8 0.0 2.2 0.0 0.0 0.0 0.0 5.7 51.5 0.0 0.2 10.1 0.6 0.0 1.7 0.0 0.0 0.1 0.3 0.1 0.2 35.8 102.9 0.0 0.8 0.1 25.7 30.3 ANKRD9 ENSG00000156381 "Ankyrin repeat domain 9" Q96BM1 14 102501767-102509799 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 112.0;skeletal muscle: 154.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.8;Early spermatids: 161.0;Erythroid cells: 146.5;Proximal enterocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055985 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055985: AB_2682996" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (3.05e-2)" "unprognostic (1.26e-2)" "unprognostic (7.76e-2)" "unprognostic (7.31e-3)" "unprognostic (6.78e-2)" "unprognostic (3.97e-2)" "unprognostic (3.35e-1)" "unprognostic (2.99e-1)" "unprognostic (3.68e-1)" "unprognostic (1.17e-1)" "prognostic favorable (1.17e-7)" "unprognostic (3.89e-1)" "unprognostic (4.74e-1)" "unprognostic (1.32e-2)" "unprognostic (1.15e-1)" 12.1 21.1 29.0 3.0 20.8 18.1 10.4 22.2 43.1 10.5 27.4 30.7 50.3 7.6 1.9 19.5 6.9 4.6 112.0 19.0 17.5 24.2 16.0 15.9 0.8 36.4 24.3 10.2 11.4 8.8 7.4 5.0 27.4 20.1 10.0 2.4 26.1 4.1 154.7 25.6 32.7 2.4 27.4 9.2 22.5 40.6 37.3 0.4 11.2 26.4 1.7 12.9 15.0 15.3 16.0 7.5 13.3 12.6 13.6 5.6 20.8 18.7 7.0 8.3 8.1 1.9 10.5 0.0 20.5 5.2 9.2 25.8 6.5 3.8 4.2 11.3 26.7 4.2 14.7 3.6 7.0 1.5 13.5 2.8 22.6 4.5 4.5 5.4 3.6 2.1 8.2 1.4 4.0 14.0 2.2 4.4 6.3 24.6 33.5 21.5 12.5 1.0 8.5 16.2 10.8 11.5 13.3 8.6 24.4 7.8 13.1 6.0 8.3 8.4 10.9 41.4 14.7 11.9 6.9 0.5 9.9 2.9 8.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 29.0 20.8 22.2 43.1 19.0 17.5 36.4 24.3 27.4 27.4 37.3 15.3 10.8 19.2 4.5 41.4 2.7 13.0 37.5 1.5 6.8 11.0 32.3 22.5 40.3 15.7 5.0 14.7 2.1 9.7 30.4 198.8 92.0 3.9 161.0 11.4 6.4 9.8 16.7 146.5 12.6 4.8 30.5 13.5 34.7 21.5 31.8 20.1 8.6 11.8 29.5 16.8 14.1 42.5 2.0 7.5 7.8 23.9 5.6 25.4 10.6 5.6 0.7 16.8 2.1 4.0 3.4 5.3 73.7 9.8 10.2 37.8 129.2 16.7 1.1 7.7 13.1 26.8 10.8 6.6 6.7 14.1 20.2 18.3 9.3 18.3 56.7 54.8 ANO9 "PIG5, TMEM16J, TP53I5" ENSG00000185101 "Anoctamin 9" A1A5B4 11 417933-442011 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.2;skin 1: 27.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.0;Intestinal goblet cells: 50.5;Paneth cells: 50.5;Proximal enterocytes: 87.7;Undifferentiated cells: 45.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 26.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 48 "B-cells: 2.1;NK-cells: 4.1;T-cells: 8.2" "Cell line enhanced" "Detected in some" "BEWO: 9.2;CAPAN-2: 29.5;HaCaT: 16.8;RPMI-8226: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039948, HPA040112" Approved Uncertain "Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA039948: AB_2676765, HPA040112: " "unprognostic (3.62e-3)" "unprognostic (2.83e-2)" "unprognostic (4.68e-2)" "unprognostic (1.62e-1)" "unprognostic (1.41e-2)" "unprognostic (8.93e-2)" "unprognostic (6.98e-2)" "unprognostic (8.94e-3)" "unprognostic (1.39e-1)" "unprognostic (2.28e-3)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (1.91e-2)" "unprognostic (1.18e-2)" "unprognostic (2.08e-1)" "unprognostic (3.92e-1)" "prognostic favorable (8.81e-4)" 0.7 0.1 0.0 7.0 0.0 2.2 1.7 0.0 0.0 1.1 0.2 16.0 34.2 0.5 7.0 6.3 1.2 2.0 0.1 0.0 0.0 3.7 0.3 2.9 12.0 0.0 0.0 0.1 6.5 0.7 1.3 0.1 0.0 2.9 9.1 0.0 3.0 0.7 0.0 27.8 30.0 0.8 0.0 4.7 7.0 0.2 0.0 9.0 2.4 0.1 8.7 2.4 3.4 0.0 2.7 0.6 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 3.1 29.5 1.9 1.4 0.0 0.1 16.8 0.0 7.0 0.0 2.1 0.0 0.0 0.6 5.1 0.0 0.4 0.0 0.0 5.6 0.0 1.2 0.1 0.0 4.5 0.1 1.9 0.0 3.8 0.5 0.1 0.0 6.0 0.0 0.1 0.0 20.6 5.1 4.4 1.6 0.0 0.3 7.3 0.0 0.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 5.5 2.1 6.5 3.3 0.0 0.8 3.7 2.8 0.0 4.1 0.0 0.0 8.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.7 0.3 9.1 5.2 4.6 15.3 6.2 0.0 5.5 3.9 2.4 8.6 9.1 3.7 0.0 0.3 3.0 81.0 0.0 10.5 0.8 4.9 1.0 0.8 15.5 0.0 0.3 6.5 3.7 0.6 29.0 11.0 0.0 0.0 0.7 0.3 0.4 0.0 0.2 50.5 14.2 0.3 1.9 0.1 0.0 1.2 3.6 0.0 1.3 0.0 0.0 0.0 0.0 9.0 50.5 0.0 5.0 2.7 87.7 3.7 9.2 0.0 0.0 0.1 1.0 0.2 0.2 7.0 6.3 0.1 12.8 0.0 45.2 5.7 ANXA11 ANX11 ENSG00000122359 "Annexin A11" P50995 10 80150889-80205572 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 443.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004851, HPA027545" Supported Supported Nucleoplasm,Cytosol NA NA 210000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB004851: AB_626682, HPA027545: AB_1844851" "unprognostic (1.85e-2)" "unprognostic (2.85e-2)" "unprognostic (5.35e-3)" "unprognostic (5.06e-2)" "unprognostic (8.18e-3)" "unprognostic (1.99e-1)" "unprognostic (4.01e-3)" "unprognostic (6.28e-2)" "unprognostic (2.32e-2)" "unprognostic (4.88e-2)" "unprognostic (3.46e-2)" "unprognostic (2.56e-2)" "prognostic favorable (6.69e-8)" "unprognostic (2.69e-3)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (2.02e-1)" 139.9 29.5 39.0 99.4 40.6 192.9 107.6 27.5 46.8 86.6 52.8 130.3 138.0 74.3 107.5 210.2 109.0 84.8 236.2 47.3 29.0 144.7 47.7 109.5 81.2 26.4 26.6 78.2 95.4 81.8 27.2 91.1 23.9 100.3 120.7 4.8 94.1 81.8 188.9 75.6 137.2 86.0 25.4 76.2 139.3 24.5 24.6 100.2 61.4 166.2 101.7 148.1 102.8 30.4 221.7 195.7 10.4 53.9 220.2 201.1 119.6 149.5 397.3 95.7 98.8 168.7 338.2 13.1 113.6 236.7 8.1 277.7 44.6 136.2 54.2 384.3 76.0 84.4 98.9 131.5 129.4 92.0 212.3 222.9 74.6 57.8 39.4 178.9 143.9 117.9 82.1 163.7 76.8 127.3 119.8 200.9 19.6 211.5 367.7 91.7 14.9 344.0 155.1 191.8 5.1 37.9 65.0 269.9 156.4 83.4 80.6 120.6 160.0 68.7 101.4 157.6 84.4 91.7 145.6 96.0 66.6 155.4 47.4 130.8 66.8 443.8 72.9 52.4 75.0 64.9 92.5 100.5 49.4 54.2 83.7 74.4 231.8 61.3 59.1 78.5 126.5 85.4 39.0 40.6 27.5 46.8 47.3 29.0 26.4 26.6 23.9 25.4 24.6 30.4 150.5 96.1 78.4 17.3 101.4 51.2 266.4 219.4 92.8 1.6 58.8 50.4 293.3 203.0 227.1 220.7 0.0 271.7 137.1 457.7 332.6 429.2 4.5 180.6 49.7 82.7 77.5 29.9 29.5 352.5 309.8 113.1 175.8 265.7 116.1 81.4 91.4 40.8 228.1 3.3 15.5 186.9 97.6 149.7 167.4 9.6 92.9 155.0 90.7 24.4 208.2 38.9 159.6 3.0 2.3 420.6 461.0 92.6 98.2 414.9 367.7 156.8 229.0 2.8 92.1 56.4 137.9 2.8 51.5 98.4 42.1 185.5 131.9 50.8 227.8 581.4 AP1G2 G2AD ENSG00000213983 "Adaptor related protein complex 1 subunit gamma 2" O75843 14 23559565-23568070 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 108.3;RT4: 151.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004106 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA004106: AB_1078172" "unprognostic (1.94e-3)" "unprognostic (2.49e-1)" "unprognostic (2.56e-2)" "unprognostic (2.73e-2)" "unprognostic (7.34e-2)" "unprognostic (6.61e-2)" "unprognostic (6.61e-2)" "unprognostic (6.28e-3)" "unprognostic (1.16e-1)" "unprognostic (8.65e-3)" "unprognostic (8.85e-2)" "unprognostic (8.40e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.30e-2)" "unprognostic (3.22e-1)" "unprognostic (2.06e-1)" "unprognostic (1.02e-3)" 15.3 18.0 31.3 23.3 35.5 30.5 20.0 34.0 40.5 22.5 27.8 27.2 28.7 11.7 14.3 35.5 19.8 18.2 6.1 32.8 30.7 26.7 15.1 18.9 39.1 29.7 28.7 23.0 36.2 24.9 67.4 12.9 29.9 33.8 23.0 9.8 29.7 15.9 2.2 45.2 37.5 10.3 27.5 45.7 35.2 7.5 30.2 30.1 27.2 1.6 42.9 26.3 26.2 30.1 29.1 30.4 0.8 3.1 4.5 7.2 45.5 3.5 8.3 10.3 13.5 28.6 64.8 53.8 15.6 2.8 0.1 53.5 16.2 45.4 7.0 30.0 9.2 20.8 14.5 67.7 16.9 31.6 108.3 20.9 66.0 7.0 24.1 11.2 6.1 37.5 9.2 22.3 4.4 70.8 26.3 28.8 6.9 59.2 11.1 38.9 0.2 16.7 41.3 151.2 8.2 11.5 15.0 68.0 5.6 17.9 40.4 7.8 5.3 2.7 20.2 2.6 0.2 16.2 9.2 21.3 1.2 21.3 3.3 40.6 25.4 43.8 29.5 35.2 28.0 30.7 31.5 31.5 42.5 28.1 25.4 24.8 10.2 38.7 37.0 22.2 42.2 35.6 31.3 35.5 34.0 40.5 32.8 30.7 29.7 28.7 29.9 27.5 30.2 30.1 9.1 19.2 21.7 6.2 31.4 13.5 18.9 33.1 29.0 31.1 23.7 21.8 0.5 17.2 38.2 12.9 2.1 22.8 23.7 38.7 5.9 30.4 1.1 9.7 4.7 9.7 32.4 9.9 21.5 29.4 24.1 7.1 64.2 15.6 31.7 22.0 6.4 2.5 15.2 72.3 15.7 29.4 42.7 15.2 21.0 1.2 9.3 15.1 10.6 6.5 27.5 8.6 12.3 4.0 4.7 26.6 53.1 6.0 14.0 11.0 33.1 9.6 24.3 6.2 0.0 1.6 5.0 5.8 3.9 16.4 9.8 24.5 30.9 13.9 34.6 23.3 AP3D1 ADTD ENSG00000065000 "Adaptor related protein complex 3 subunit delta 1" O14617 19 2100988-2164468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074408 Approved Cytosol No No 28000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA074408: AB_2686686" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.24e-3)" "unprognostic (1.37e-1)" "unprognostic (6.35e-2)" "prognostic unfavorable (9.23e-4)" "unprognostic (4.24e-2)" "unprognostic (8.05e-2)" "unprognostic (5.70e-2)" "unprognostic (6.68e-3)" "unprognostic (9.37e-2)" "prognostic favorable (2.61e-6)" "unprognostic (8.11e-3)" "unprognostic (1.22e-1)" "unprognostic (6.25e-2)" "unprognostic (1.73e-2)" 30.0 40.7 39.0 36.3 39.0 27.6 28.8 29.4 55.1 29.5 39.4 36.2 35.8 35.1 16.6 38.2 32.5 28.0 43.7 45.0 39.8 35.8 40.9 31.1 37.2 39.4 43.3 29.8 63.9 40.0 56.4 33.4 48.0 31.3 22.5 29.6 48.0 34.0 61.1 30.0 35.4 32.8 26.0 34.8 37.7 44.9 38.9 33.2 43.9 40.3 27.6 34.3 25.5 34.5 114.8 117.5 68.5 105.0 85.7 71.8 83.9 90.3 87.9 94.2 85.2 134.8 61.8 61.7 51.0 134.1 115.7 76.4 99.2 109.7 61.1 89.9 94.6 80.5 74.7 106.3 149.9 88.4 102.5 89.5 72.3 98.1 141.6 79.7 92.6 44.2 84.2 210.9 84.1 84.4 85.6 46.8 102.8 78.2 74.2 90.3 75.0 83.4 70.7 162.7 97.4 81.1 82.3 85.7 154.2 62.5 83.2 101.0 121.7 89.7 37.7 123.4 106.7 176.5 184.6 78.6 122.5 57.4 91.5 0.2 3.3 2.9 3.5 3.6 5.6 2.4 3.4 4.1 3.9 2.9 2.7 3.4 3.4 5.5 3.0 7.5 2.1 2.2 39.0 39.0 29.4 55.1 45.0 39.8 39.4 43.3 48.0 26.0 38.9 34.5 29.5 60.9 61.7 41.4 35.5 20.3 41.3 20.3 36.5 66.6 39.5 26.5 77.7 44.3 34.1 40.5 35.5 55.3 32.5 79.5 21.5 53.3 70.7 34.4 36.9 37.1 47.8 42.9 24.1 74.2 71.9 38.2 69.8 48.9 17.1 38.9 29.6 49.2 66.9 48.8 30.2 68.8 18.3 38.4 30.2 68.6 37.9 43.4 39.2 18.7 31.7 55.5 29.9 21.1 28.3 67.7 54.0 38.0 67.6 65.5 52.6 36.0 30.3 43.9 19.7 37.8 33.6 105.3 129.5 38.0 23.3 78.0 36.9 39.6 56.8 59.4 AP3S2 sigma3b ENSG00000157823 "Adaptor related protein complex 3 subunit sigma 2" P59780 15 89830599-89894638 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA049270: AB_2680696" "unprognostic (1.46e-1)" "unprognostic (1.60e-2)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (2.68e-1)" "unprognostic (3.78e-2)" "unprognostic (5.27e-2)" "unprognostic (3.03e-1)" "unprognostic (7.59e-2)" "unprognostic (1.22e-1)" "unprognostic (4.31e-2)" "prognostic favorable (5.55e-16)" "unprognostic (7.97e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (8.67e-3)" 24.2 20.3 15.1 11.2 15.8 10.4 19.4 14.9 18.1 17.3 13.3 19.3 10.9 13.0 16.3 20.7 17.3 17.5 30.7 15.0 17.0 36.5 40.5 16.3 12.9 16.0 18.4 20.0 19.0 32.6 9.0 18.5 18.4 15.3 19.2 44.0 13.5 21.4 44.8 8.7 10.2 18.0 15.0 12.6 10.0 12.5 16.7 20.1 26.2 45.2 17.7 15.3 6.8 16.7 13.5 60.6 33.4 35.6 66.7 45.6 28.0 58.8 75.2 74.3 59.7 26.0 34.8 12.1 51.3 39.1 48.9 31.0 57.4 33.1 58.3 51.2 29.0 37.3 25.4 33.6 28.1 16.1 22.3 30.9 40.4 20.7 41.6 40.6 38.8 30.8 29.1 32.8 48.0 27.7 27.6 8.7 37.2 68.5 11.6 15.9 33.8 25.0 42.1 35.9 25.5 22.3 69.4 43.1 40.4 69.8 26.9 14.1 16.3 40.0 19.2 62.1 19.6 28.3 94.5 28.9 35.8 18.7 24.1 6.3 16.6 7.8 5.0 15.4 7.8 4.5 7.2 7.4 11.6 6.3 5.7 4.0 16.1 8.3 19.9 7.4 8.4 10.6 15.1 15.8 14.9 18.1 15.0 17.0 16.0 18.4 18.4 15.0 16.7 16.7 5.9 12.8 15.4 0.0 5.9 3.3 4.0 6.0 5.2 22.0 8.0 5.7 18.2 10.0 11.2 5.5 35.5 8.9 6.1 34.4 9.8 13.4 3.1 5.9 10.8 7.2 14.4 5.0 0.0 16.1 4.2 9.0 8.2 7.1 8.2 15.4 8.9 17.0 6.4 18.5 0.0 11.4 2.0 12.0 6.4 3.2 7.2 9.7 8.8 0.0 16.9 17.3 9.2 0.0 0.0 13.4 16.4 7.5 8.6 5.8 15.8 13.7 9.8 30.6 0.0 6.1 6.0 11.6 8.3 6.1 2.8 6.4 6.2 28.5 15.2 4.2 AP5Z1 "KIAA0415, SPG48, zeta" ENSG00000242802 "Adaptor related protein complex 5 subunit zeta 1" O43299 7 4775615-4794397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035693 Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Nucleoplasm "HPA035693: AB_10960687" "unprognostic (1.64e-1)" "unprognostic (5.22e-2)" "unprognostic (3.01e-3)" "unprognostic (4.24e-2)" "unprognostic (2.43e-3)" "unprognostic (5.19e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-3)" "unprognostic (1.26e-2)" "unprognostic (5.32e-3)" "unprognostic (8.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-2)" "unprognostic (2.22e-1)" 14.8 18.5 7.0 0.7 7.1 1.5 11.8 7.3 10.0 12.4 5.8 13.2 1.1 13.4 1.0 11.0 11.0 0.8 7.7 6.9 5.7 9.2 9.2 12.9 1.8 8.3 6.5 11.8 9.9 0.7 9.8 1.1 7.4 11.7 0.4 0.6 12.4 0.7 8.5 21.8 15.5 0.4 5.9 22.9 12.0 8.6 7.4 0.9 11.2 0.2 0.6 13.4 10.9 7.3 2.8 4.2 0.7 2.4 1.0 0.9 4.3 1.3 1.9 2.0 1.7 5.2 3.5 1.6 1.8 0.9 5.1 5.4 0.7 0.5 0.6 1.8 3.5 2.4 4.5 4.6 3.0 2.5 5.1 2.2 1.6 1.8 1.3 0.7 0.5 2.2 3.4 1.1 1.2 7.7 0.3 15.0 5.9 0.3 4.3 2.9 2.6 4.8 1.0 4.4 1.7 3.0 1.8 8.7 6.4 0.5 6.4 8.9 3.8 2.3 4.4 6.5 1.7 8.5 7.4 2.3 1.7 5.6 3.6 1.9 2.3 2.9 2.4 2.8 1.4 1.9 1.8 2.4 1.2 1.8 2.5 2.2 2.2 2.4 2.5 2.4 1.8 1.3 7.0 7.1 7.3 10.0 6.9 5.7 8.3 6.5 7.4 5.9 7.4 7.3 12.4 9.6 15.0 7.5 18.2 6.9 2.9 8.8 8.0 10.5 5.7 5.8 4.3 15.7 6.6 11.0 4.2 11.5 20.3 20.1 0.0 14.1 2.2 9.9 10.1 11.6 12.0 5.0 12.4 13.6 7.7 9.9 21.4 16.4 17.1 14.3 12.5 8.1 28.7 18.5 10.7 15.1 10.2 12.3 10.7 1.5 13.4 16.3 14.2 13.1 23.4 8.2 21.6 10.6 12.6 20.6 15.9 10.9 19.8 4.9 14.7 6.8 8.3 9.4 0.0 5.8 9.5 8.1 10.8 7.6 11.1 16.6 15.6 12.6 14.1 3.8 APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674014-49683971 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol No No 2300000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA029700: AB_10599278, HPA029701: AB_10600333, HPA029702: AB_10602411, HPA029703: AB_10601348" "unprognostic (4.93e-2)" "unprognostic (5.42e-2)" "unprognostic (6.04e-3)" "unprognostic (2.71e-1)" "unprognostic (9.32e-2)" "unprognostic (8.20e-2)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (8.03e-2)" "unprognostic (3.21e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.32e-10)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.34e-2)" "unprognostic (7.67e-2)" 21.7 43.6 18.0 30.7 18.0 42.3 26.8 17.9 22.8 24.8 27.7 48.5 48.6 19.7 24.7 40.2 33.7 22.3 40.6 17.7 19.9 65.8 63.3 26.8 35.2 19.2 21.3 24.6 34.8 63.0 38.3 31.9 24.3 31.0 51.7 12.9 34.0 29.5 103.8 32.8 35.1 28.1 16.8 27.2 35.5 18.7 20.0 37.3 48.6 103.9 43.4 35.0 21.2 16.7 101.2 79.2 84.2 110.8 71.3 48.3 113.6 64.2 79.3 87.4 91.2 130.1 101.7 127.1 70.0 71.7 78.9 89.8 95.1 143.4 64.2 61.9 41.0 138.8 123.4 105.1 72.0 145.5 204.7 55.0 106.5 49.2 101.4 85.5 78.7 86.4 86.6 59.8 86.0 90.8 105.3 76.6 50.4 140.5 75.3 38.4 72.8 165.1 169.9 226.7 40.4 71.2 72.4 166.7 78.9 61.0 112.1 77.2 36.1 53.8 93.0 83.6 86.8 69.8 54.5 77.7 91.7 104.1 78.7 57.9 43.0 52.8 44.8 47.6 34.8 33.3 36.3 41.9 43.6 27.6 37.9 37.4 13.6 39.0 47.6 35.1 50.4 51.9 18.0 18.0 17.9 22.8 17.7 19.9 19.2 21.3 24.3 16.8 20.0 16.7 5.4 41.7 25.3 7.5 20.1 8.7 23.3 50.2 11.4 6.8 20.8 15.9 46.8 30.0 39.4 27.6 12.5 83.7 16.5 83.2 43.0 44.4 6.4 16.6 13.8 9.0 26.5 43.8 4.8 34.7 64.8 16.4 41.8 20.5 23.5 20.0 13.2 74.7 51.1 8.4 4.7 47.1 63.1 35.9 11.9 10.9 15.2 23.2 21.4 2.8 26.8 30.4 27.8 3.0 2.0 39.0 35.8 13.5 39.4 18.0 85.4 80.7 19.4 11.1 13.1 10.6 25.2 33.2 28.5 30.6 9.2 62.1 23.9 28.5 74.0 23.7 APOBR "APOB100R, APOB48R" ENSG00000184730 "Apolipoprotein B receptor" Q0VD83 16 28494643-28498970 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 34.9;intestine: 26.3;lung: 11.6;lymphoid tissue: 36.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 149.9;granulocytes: 39.3;Intestinal goblet cells: 47.5;NK-cells: 65.9;Paneth cells: 84.8;Undifferentiated cells: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 41.6;HMC-1: 124.8;NB-4: 35.7;THP-1: 25.8;U-937: 30.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041667, HPA042093" Enhanced NA NA 700000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041667: AB_10793972, HPA042093: AB_10795393" "unprognostic (3.16e-1)" "unprognostic (8.01e-3)" "unprognostic (6.19e-3)" "prognostic favorable (3.26e-4)" "unprognostic (5.48e-2)" "unprognostic (4.79e-3)" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-2)" "unprognostic (7.60e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.25e-2)" 3.3 2.0 0.9 20.0 0.9 34.9 1.6 1.1 2.0 1.3 0.9 26.3 6.1 1.1 1.4 1.6 2.4 2.8 1.3 0.9 1.7 1.1 2.7 11.6 6.7 2.3 1.3 0.4 1.3 0.6 0.7 2.7 1.8 1.8 16.1 0.1 2.1 3.5 1.1 3.1 9.4 2.7 1.5 36.6 4.1 1.3 2.6 3.7 1.2 1.1 3.8 4.8 1.1 2.2 0.1 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.2 2.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 41.6 0.3 0.5 0.0 15.4 124.8 0.0 0.1 0.0 0.0 0.1 0.0 0.4 1.3 0.7 0.0 1.2 1.5 35.7 0.0 0.0 0.0 0.9 0.1 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.1 0.1 1.4 25.8 0.1 0.0 0.0 0.1 0.0 0.7 0.3 1.5 0.1 30.8 0.1 10.5 5.8 16.5 2.4 2.9 2.3 0.0 1.3 2.4 5.0 0.1 0.3 1.2 17.1 7.3 2.6 0.9 0.4 2.3 0.9 0.9 1.1 2.0 0.9 1.7 2.3 1.3 1.8 1.5 2.6 2.2 0.3 3.2 7.7 0.0 2.2 0.8 0.2 0.1 0.0 0.0 2.2 0.6 0.6 0.0 2.7 3.7 0.0 2.1 21.9 149.9 0.0 0.0 0.1 0.2 0.2 0.7 9.1 6.5 0.0 0.2 14.6 1.0 1.1 0.2 39.3 0.1 0.7 0.6 32.3 0.0 0.0 47.5 0.0 30.1 32.5 0.4 0.3 33.9 1.8 1.9 34.8 0.0 65.9 0.0 0.1 0.0 84.8 0.0 5.7 0.1 6.5 0.1 0.8 0.0 6.6 0.0 0.4 0.4 0.3 0.0 0.3 5.9 16.0 0.0 49.3 0.4 APPL2 "DIP13B, FLJ10659" ENSG00000136044 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2" Q8NEU8 12 105173297-105236203 "Disease related genes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 171.2;Microglial cells: 112.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 177.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039688, HPA043925" Approved NA NA 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA039688: AB_2676626, HPA043925: AB_2678733" "unprognostic (3.46e-1)" "unprognostic (4.21e-1)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.54e-2)" "unprognostic (2.41e-2)" "unprognostic (6.66e-3)" "unprognostic (8.43e-2)" "unprognostic (5.50e-2)" "unprognostic (5.71e-3)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "prognostic favorable (7.65e-4)" "unprognostic (1.87e-1)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" "unprognostic (9.32e-2)" 34.1 29.2 33.1 18.5 35.9 37.0 35.2 41.0 35.5 33.0 29.8 54.1 38.8 26.3 19.0 23.4 20.7 34.4 16.3 30.6 34.6 20.7 16.1 18.4 22.7 36.5 34.4 28.8 23.8 23.2 19.7 23.1 37.7 38.8 54.7 33.5 22.2 26.9 14.5 66.6 57.6 22.1 33.0 22.9 31.7 36.6 36.5 20.0 16.2 12.8 17.7 16.6 27.8 38.6 15.5 23.2 37.8 22.9 111.9 80.5 27.6 114.4 110.1 40.0 24.3 27.7 11.8 13.5 21.6 177.9 15.3 18.1 19.2 24.6 49.0 6.8 16.6 7.4 11.4 12.4 18.1 5.5 7.4 42.6 22.9 31.6 35.4 77.4 17.2 18.2 8.4 17.5 90.9 20.9 10.6 17.6 27.8 33.1 33.1 8.3 24.9 25.3 33.4 31.9 25.7 48.1 38.4 17.0 19.3 26.6 28.3 10.1 16.7 61.7 14.8 30.4 19.4 15.9 13.7 9.9 39.6 7.3 34.4 0.2 4.7 10.7 1.6 3.7 1.3 0.4 0.6 0.9 3.2 2.8 0.9 1.4 21.1 4.6 6.2 1.0 2.3 1.7 33.1 35.9 41.0 35.5 30.6 34.6 36.5 34.4 37.7 33.0 36.5 38.6 16.0 19.2 13.2 95.3 6.1 12.7 13.0 6.5 12.0 30.6 18.0 14.1 13.2 28.6 10.6 11.0 10.4 19.9 12.1 171.2 5.9 24.2 6.8 33.8 23.0 15.7 30.0 2.5 50.2 18.9 19.0 22.8 15.8 20.7 8.2 46.0 16.4 6.5 30.3 10.1 51.8 40.0 12.2 23.3 8.3 8.6 23.6 18.9 16.0 112.4 10.3 39.9 10.3 91.5 75.1 26.4 38.1 21.8 6.0 29.4 101.5 16.6 56.2 16.2 19.7 18.9 13.2 15.6 23.7 14.3 19.0 23.1 8.0 25.0 17.5 14.2 AQP8 ENSG00000103375 "Aquaporin 8" O94778 16 25215731-25228932 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 641 "intestine: 330.0;pancreas: 1280.1" "Group enriched" "Detected in some" 45 "Distal enterocytes: 1005.1;Paneth cells: 379.5" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.4;pancreatic cancer: 15.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "Hep G2: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046259 Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046259: AB_10960494" "unprognostic (8.75e-2)" "unprognostic (2.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.93e-2)" "unprognostic (8.67e-2)" "unprognostic (3.34e-3)" "unprognostic (8.47e-2)" "unprognostic (1.36e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-1)" "unprognostic (2.05e-2)" "unprognostic (8.23e-2)" "unprognostic (1.06e-2)" "unprognostic (2.67e-2)" "unprognostic (1.82e-1)" "unprognostic (1.97e-2)" "unprognostic (3.71e-2)" 0.3 0.2 0.6 0.4 0.7 0.4 0.3 0.7 0.8 0.5 0.3 330.0 0.2 0.5 0.0 0.1 0.3 0.0 0.2 0.7 0.5 0.2 0.7 0.1 0.0 0.4 0.4 0.6 1280.1 0.0 0.1 0.1 0.4 0.3 160.3 0.1 0.1 0.3 0.1 0.4 0.2 1.2 0.4 0.1 0.8 0.5 0.6 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.8 0.7 0.5 0.4 0.4 0.4 0.4 0.6 0.6 0.2 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1005.1 0.0 0.1 1.4 0.2 1.3 0.1 13.1 0.0 0.8 11.0 0.1 0.0 0.0 0.3 8.9 0.4 0.0 0.0 0.1 1.7 0.6 15.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.6 379.5 0.0 0.1 0.2 0.0 0.1 0.0 0.4 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.4 1.7 0.2 12.9 0.1 ARF3 ENSG00000134287 "ADP ribosylation factor 3" P61204 12 48935723-48957487 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.99e-2)" "unprognostic (2.40e-1)" "unprognostic (9.60e-2)" "unprognostic (1.58e-2)" "unprognostic (9.12e-3)" "unprognostic (2.25e-3)" "unprognostic (2.00e-3)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.55e-1)" "unprognostic (1.57e-3)" "unprognostic (1.64e-1)" "unprognostic (3.88e-2)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" 63.1 73.4 113.5 79.9 151.8 66.7 53.1 53.9 154.2 66.9 31.4 98.0 57.7 59.8 71.0 79.5 59.2 46.6 45.2 167.5 102.3 85.6 45.9 71.0 50.6 70.1 77.1 47.3 46.3 138.1 75.2 58.6 71.7 55.2 89.0 78.0 55.1 59.2 16.9 68.2 65.4 72.0 70.2 60.7 55.3 48.9 128.4 73.3 69.5 16.7 69.8 64.8 51.0 100.4 212.1 305.2 131.0 116.7 106.5 77.4 124.8 137.8 173.0 158.5 136.4 407.0 272.1 168.6 201.4 151.2 124.4 171.7 182.9 186.8 142.4 206.8 94.2 274.5 243.0 118.3 66.5 212.1 213.5 87.4 145.2 172.8 102.3 172.1 170.9 111.8 170.4 89.0 137.1 256.7 158.1 116.7 185.4 338.5 162.4 150.4 75.0 111.6 173.3 265.7 134.7 122.7 148.6 171.2 129.7 144.4 290.1 167.1 238.8 117.3 187.1 74.2 87.3 86.0 210.4 123.0 154.7 162.0 68.4 5.7 39.0 27.7 13.5 25.2 10.6 13.1 15.6 16.8 52.1 12.7 8.4 9.8 54.8 18.7 17.1 40.2 14.0 21.3 113.5 151.8 53.9 154.2 167.5 102.3 70.1 77.1 71.7 70.2 128.4 100.4 35.8 25.6 33.2 19.6 31.4 60.3 41.5 92.2 61.5 34.5 60.2 40.6 10.1 54.3 47.4 99.3 10.4 56.4 54.4 228.4 66.5 114.8 49.9 41.3 31.8 55.0 70.8 26.5 44.3 90.7 119.8 42.7 34.1 48.9 27.9 59.5 57.5 48.7 132.8 43.7 36.8 71.5 75.3 86.9 81.2 101.9 40.7 79.9 44.4 18.7 128.1 57.4 50.4 14.6 20.6 103.2 176.3 37.2 37.6 60.5 78.9 143.3 45.8 24.1 32.9 24.0 52.3 52.6 63.8 61.6 65.8 69.0 31.3 43.2 67.3 56.7 ARFGAP1 "ARF1GAP, bA261N11.3, FLJ10767" ENSG00000101199 "ADP ribosylation factor GTPase activating protein 1" Q8N6T3 20 63272785-63289790 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051019, HPA056273" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles" Cytosol "HPA051019: AB_2681313, HPA056273: AB_2683084" "unprognostic (1.81e-1)" "unprognostic (4.64e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-1)" "unprognostic (1.38e-1)" "unprognostic (1.24e-1)" "unprognostic (1.57e-3)" "unprognostic (7.76e-2)" "unprognostic (8.86e-3)" "unprognostic (8.62e-2)" "prognostic favorable (4.57e-4)" "unprognostic (3.23e-2)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.16e-1)" "unprognostic (7.59e-2)" "unprognostic (4.34e-2)" "unprognostic (2.86e-1)" 12.9 16.7 13.1 15.5 14.3 12.1 13.0 13.1 20.6 19.1 8.4 19.1 13.1 20.8 8.6 15.8 16.1 16.8 14.1 14.4 11.0 15.9 17.8 16.1 16.1 14.1 12.0 17.7 28.3 11.8 63.9 15.4 14.2 20.1 9.5 11.7 18.4 13.4 14.1 19.1 18.1 12.5 9.1 20.5 18.5 24.2 12.5 14.2 17.9 7.5 11.3 16.5 14.9 15.9 32.6 60.2 25.6 30.6 30.3 32.5 51.2 46.4 36.5 90.7 45.5 145.2 35.2 24.5 41.7 55.4 41.5 43.2 23.5 73.8 28.5 15.8 26.7 19.4 64.7 128.4 46.2 28.8 38.4 28.5 46.9 44.0 24.9 30.5 32.9 25.5 34.9 27.8 25.1 53.2 52.9 28.0 34.5 34.3 51.9 29.7 36.8 23.6 22.3 38.8 27.3 29.9 55.1 58.7 59.2 20.7 42.8 36.4 42.8 56.0 77.3 35.0 37.6 28.4 20.2 26.5 56.9 20.0 35.3 4.8 5.7 6.4 5.6 7.1 6.4 3.0 3.1 5.3 5.7 4.2 3.0 3.0 2.4 4.7 9.5 4.2 4.1 6.0 13.1 14.3 13.1 20.6 14.4 11.0 14.1 12.0 14.2 9.1 12.5 15.9 12.6 22.4 30.7 34.9 11.2 10.1 6.0 8.6 4.0 26.6 17.6 14.4 12.4 11.5 14.4 12.9 33.3 12.5 15.4 37.6 9.8 12.2 15.9 11.0 17.1 14.2 24.5 9.5 14.5 15.4 24.9 16.3 50.4 14.9 15.9 30.6 13.6 23.3 14.9 21.9 14.9 40.4 2.0 14.4 11.5 23.3 12.5 13.5 12.4 5.6 12.3 11.8 15.5 18.6 24.8 28.2 18.3 9.8 17.8 11.6 17.4 11.5 18.8 20.1 6.6 11.1 14.9 21.3 7.4 6.7 8.5 15.2 10.3 16.8 24.0 9.2 ARFRP1 "ARL18, ARP, Arp1" ENSG00000101246 "ADP ribosylation factor related protein 1" Q13795 20 63698642-63708025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047028, HPA050634" Approved Supported "Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA047028: AB_2679908, HPA050634: AB_2681196" "unprognostic (6.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.95e-2)" "unprognostic (6.03e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-1)" "unprognostic (1.36e-3)" "unprognostic (2.13e-2)" "unprognostic (9.70e-2)" "unprognostic (2.25e-2)" "unprognostic (3.22e-2)" "unprognostic (6.53e-2)" "unprognostic (5.58e-2)" "unprognostic (3.93e-2)" "unprognostic (1.72e-2)" "unprognostic (5.48e-2)" "unprognostic (3.39e-1)" 26.8 27.8 23.4 14.0 23.4 10.0 25.0 22.8 29.1 31.8 22.4 29.3 18.9 29.3 5.3 36.2 27.9 8.8 41.0 22.7 22.7 34.1 36.5 26.0 17.8 23.1 23.2 29.3 24.4 12.6 25.1 11.6 23.1 32.4 8.4 5.5 22.4 16.0 31.8 22.9 27.2 10.1 22.7 42.0 24.6 20.1 24.5 17.7 25.6 15.5 11.2 29.5 28.3 23.9 26.5 31.9 10.1 10.6 10.0 10.8 14.6 31.8 21.1 67.7 24.6 60.0 22.4 32.4 21.6 18.8 27.3 35.8 11.0 35.5 11.9 11.3 16.5 23.8 36.1 52.2 34.7 27.3 21.5 15.1 45.2 17.8 21.6 17.9 25.1 30.5 36.0 24.1 16.9 14.9 54.0 37.7 15.8 19.5 46.7 42.3 14.0 33.4 14.5 21.7 16.9 17.3 32.3 46.5 11.4 6.1 20.5 34.8 20.0 39.6 15.9 14.9 32.6 24.9 11.1 25.1 26.5 17.9 22.8 44.3 30.9 23.5 41.5 31.6 34.7 32.6 37.5 39.8 28.3 33.7 46.8 41.5 15.7 37.6 34.7 49.2 32.3 36.5 23.4 23.4 22.8 29.1 22.7 22.7 23.1 23.2 23.1 22.7 24.5 23.9 40.7 12.8 11.9 12.4 25.9 13.9 25.5 26.1 19.4 44.6 20.8 28.7 34.0 8.6 15.8 25.8 20.9 42.2 28.0 48.9 39.2 31.2 12.8 13.5 27.0 34.3 26.4 25.7 10.6 20.4 25.5 31.6 18.3 10.7 24.7 28.4 24.3 18.4 36.9 37.0 10.6 31.6 18.3 20.7 15.3 10.5 23.9 24.1 24.9 5.6 41.0 40.8 29.9 4.0 11.9 51.6 34.6 29.7 23.4 22.9 52.4 33.4 12.3 42.3 19.7 21.8 35.1 44.5 32.7 22.4 14.2 30.2 30.7 35.7 33.1 17.0 ARHGAP27 "CAMGAP1, FLJ43547, SH3D20, SH3P20" ENSG00000159314 "Rho GTPase activating protein 27" Q6ZUM4 17 45393902-45434421 "Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.1;Paneth cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 16.7;OE19: 20.5;RT4: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023919, HPA053053" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA023919: AB_2059402, HPA053053: AB_2682027" "unprognostic (9.80e-2)" "unprognostic (1.36e-1)" "unprognostic (7.34e-2)" "unprognostic (4.89e-3)" "unprognostic (4.66e-1)" "unprognostic (2.69e-2)" "unprognostic (7.69e-2)" "unprognostic (6.89e-2)" "unprognostic (2.26e-1)" "unprognostic (2.33e-1)" "unprognostic (1.49e-2)" "unprognostic (1.96e-3)" "unprognostic (5.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.21e-4)" 16.2 7.3 4.3 8.6 6.7 11.6 15.8 4.0 4.8 27.1 3.1 39.6 10.5 8.7 1.7 98.0 11.7 3.2 22.7 3.7 4.0 20.4 6.5 28.4 9.1 5.4 4.5 3.6 7.7 3.1 10.4 4.0 4.7 17.0 8.9 0.5 37.7 1.5 4.4 27.3 51.6 2.4 4.4 63.0 12.7 8.9 5.5 6.3 16.7 1.8 6.7 17.6 44.2 4.3 6.1 6.0 0.1 1.7 0.8 0.4 16.7 0.0 0.3 0.4 0.1 5.3 11.9 5.5 11.4 0.4 2.6 3.8 0.8 1.1 0.2 11.3 3.7 0.3 2.7 3.5 0.1 0.0 15.7 0.8 4.7 0.0 1.7 0.5 3.6 5.9 1.5 9.8 0.5 4.2 5.3 1.9 0.3 20.5 4.9 4.4 0.2 1.9 3.9 26.1 0.8 0.5 0.7 5.0 0.3 2.0 3.9 10.2 5.6 0.0 1.4 0.1 0.5 12.0 8.4 1.2 0.3 1.5 0.1 1.0 5.2 4.4 2.4 8.6 1.5 3.6 1.5 2.7 4.3 2.7 1.2 1.3 10.0 1.8 11.4 7.2 2.1 4.0 4.3 6.7 4.0 4.8 3.7 4.0 5.4 4.5 4.7 4.4 5.5 4.3 19.9 6.4 17.8 2.9 23.1 10.3 15.2 9.3 2.8 3.3 11.4 7.4 10.6 15.7 13.0 18.4 4.2 7.7 38.0 99.1 3.9 6.0 1.1 11.0 2.5 20.8 19.2 1.7 3.6 3.4 11.5 3.1 31.6 18.4 4.5 0.5 17.5 2.1 15.0 1.7 8.8 34.2 10.2 47.1 13.4 1.1 0.3 33.1 7.2 19.7 26.0 1.6 23.7 3.0 2.5 19.1 79.6 0.0 15.9 28.3 57.0 6.4 11.7 1.6 0.0 3.0 2.9 6.7 2.0 9.7 8.7 14.1 14.2 1.0 43.4 57.4 ARHGEF10L "FLJ10521, KIAA1626" ENSG00000074964 "Rho guanine nucleotide exchange factor 10 like" Q9HCE6 1 17539698-17697874 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 41 "classical monocyte: 18.8;intermediate monocyte: 18.0;myeloid DC: 13.4;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 48 "dendritic cells: 13.4;monocytes: 18.8" "Cell line enhanced" "Detected in many" "Hep G2: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026426, HPA026440, HPA028115" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "HPA026426: AB_10599487, HPA026440: AB_10599422, HPA028115: AB_10602285" "unprognostic (4.34e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-2)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "prognostic favorable (8.13e-5)" "unprognostic (3.61e-2)" "unprognostic (7.90e-2)" "unprognostic (2.10e-2)" "unprognostic (1.75e-3)" "unprognostic (1.94e-3)" "unprognostic (5.83e-2)" "prognostic favorable (5.65e-4)" "unprognostic (4.11e-2)" "unprognostic (1.66e-1)" "unprognostic (8.17e-2)" "unprognostic (5.21e-3)" 22.2 10.5 11.9 11.4 10.9 1.7 16.5 38.7 11.4 24.2 13.8 29.4 15.9 16.2 4.6 28.1 16.0 11.9 30.2 10.3 12.2 32.5 87.5 13.0 4.5 19.4 18.5 10.4 43.9 17.0 7.9 5.9 19.4 18.4 12.9 4.0 25.9 19.5 66.2 40.9 21.7 8.7 10.9 9.7 20.8 3.7 17.7 1.6 18.0 35.5 4.3 24.6 21.7 9.3 8.0 9.1 11.3 3.9 19.1 6.3 7.6 5.4 10.6 6.3 5.3 9.5 23.6 0.0 9.8 10.2 8.8 6.0 1.6 2.9 1.2 0.2 2.9 0.0 9.5 26.9 4.2 0.0 0.0 8.5 5.5 3.9 1.1 12.7 1.2 0.0 0.0 0.2 17.8 7.7 0.0 0.2 4.9 12.2 0.0 0.0 4.5 3.0 13.4 16.4 16.5 12.2 4.2 2.9 12.3 3.2 11.0 9.5 0.0 5.5 6.5 6.5 2.3 0.0 2.5 0.0 8.5 0.2 3.0 0.0 18.8 0.0 0.0 18.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 7.6 11.9 10.9 38.7 11.4 10.3 12.2 19.4 18.5 19.4 10.9 17.7 9.3 1.3 3.2 7.4 82.6 1.0 5.7 5.3 7.2 5.2 16.1 13.7 12.3 36.4 20.0 13.9 31.3 2.1 0.7 0.1 41.6 9.8 19.8 15.9 3.4 4.2 2.1 37.8 2.7 16.7 20.3 0.6 8.5 17.9 6.5 0.0 3.9 2.5 43.7 26.0 10.1 23.8 45.5 8.2 8.6 26.4 8.9 5.0 18.6 3.6 19.7 9.6 14.6 0.0 24.6 7.1 11.7 24.9 6.8 0.2 5.9 13.6 18.3 9.4 5.4 13.1 10.8 18.3 11.9 1.6 8.0 8.7 1.0 0.6 0.3 46.1 12.1 ARHGEF16 "GEF16, NBR" ENSG00000130762 "Rho guanine nucleotide exchange factor 16" Q5VV41 1 3454665-3481113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.1;Extravillous trophoblasts: 55.6;Gastric mucus-secreting cells: 67.2;Intestinal goblet cells: 49.6;Paneth cells: 68.2;Proximal enterocytes: 72.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.4;MCF7: 32.4;OE19: 38.2;SK-BR-3: 34.9" "Region enhanced" "Detected in many" "olfactory bulb: 4.7" "Low region specificity" "Detected in many" HPA010609 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA010609: AB_1845004" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (4.31e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (5.39e-2)" "unprognostic (9.16e-2)" "prognostic favorable (1.24e-10)" "unprognostic (6.46e-2)" "unprognostic (2.86e-1)" "unprognostic (1.71e-2)" "unprognostic (3.29e-2)" 3.8 0.5 1.4 2.7 2.0 0.0 4.8 3.0 2.0 3.5 5.2 19.7 44.0 1.1 2.7 17.9 2.5 11.1 1.0 1.1 4.0 17.7 6.5 3.3 0.2 5.3 2.6 1.3 11.1 8.0 11.4 5.0 5.1 9.4 11.9 2.7 17.0 5.7 1.4 5.9 34.2 0.5 2.6 0.8 28.1 3.2 3.3 0.4 10.0 1.5 2.0 5.0 9.0 3.3 18.3 6.8 1.8 0.2 0.0 0.0 12.6 0.3 0.4 0.5 1.4 20.7 56.4 0.0 13.5 0.1 3.4 18.8 3.0 12.1 0.1 0.0 6.3 0.0 8.8 16.2 0.6 0.0 0.1 0.3 11.4 1.2 0.6 1.2 0.1 0.3 2.3 0.0 0.1 32.4 0.0 0.4 13.8 38.2 0.4 0.0 0.0 2.7 14.2 9.1 9.8 1.8 3.6 34.9 0.8 7.1 15.7 0.6 0.0 0.2 4.0 0.3 0.4 0.1 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.0 3.0 2.0 1.1 4.0 5.3 2.6 5.1 2.6 3.3 3.3 0.6 9.6 5.4 2.0 0.5 3.2 15.0 9.1 14.2 1.1 8.1 4.6 1.6 12.8 11.7 16.5 6.2 3.2 0.1 101.1 15.6 16.5 0.1 4.3 0.8 0.8 10.2 0.0 0.4 12.7 55.6 0.8 67.2 9.9 0.0 17.3 0.4 4.3 1.2 3.3 0.5 49.6 20.3 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.6 36.7 0.0 0.5 5.2 28.6 68.2 0.0 2.8 3.6 72.1 11.5 6.5 8.8 0.0 0.0 3.0 0.3 3.9 12.2 1.0 6.7 0.5 2.0 40.0 13.3 ARL14 "ARF7, FLJ22595" ENSG00000179674 "ADP ribosylation factor like GTPase 14" Q8N4G2 3 160677160-160678448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 129.2;intestine: 51.2;stomach 1: 77.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 588.3;Gastric mucus-secreting cells: 377.7;Intestinal goblet cells: 154.6;Paneth cells: 519.2;Proximal enterocytes: 174.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 6.6;pancreatic cancer: 26.0;stomach cancer: 14.3;urothelial cancer: 8.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 15 "memory B-cell: 1.8" "Lineage enriched" "Detected in single" 18 "B-cells: 1.8" "Cell line enhanced" "Detected in some" "A-431: 9.7;CAPAN-2: 36.2;HaCaT: 9.0;OE19: 25.3;RT4: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.65e-1)" "unprognostic (7.26e-3)" "unprognostic (2.64e-2)" "unprognostic (3.70e-3)" "unprognostic (6.36e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.30e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (6.71e-4)" "unprognostic (4.74e-2)" "unprognostic (4.91e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-1)" "unprognostic (1.62e-1)" "unprognostic (1.70e-2)" 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 51.2 0.1 0.0 1.0 0.1 129.2 0.0 0.0 0.0 0.4 1.4 0.0 0.2 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.1 36.0 0.0 0.1 0.0 0.0 0.2 34.2 2.8 0.0 0.1 77.2 0.0 0.0 0.3 0.6 0.0 3.2 23.8 0.3 0.0 9.7 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 36.2 0.0 0.8 0.0 4.2 9.0 0.0 0.9 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.3 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 25.3 2.0 0.0 0.0 0.3 2.9 17.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.0 1.9 4.5 2.6 0.0 0.0 0.2 0.1 0.0 18.6 1.2 0.0 0.0 0.0 0.0 588.3 0.0 12.6 0.0 5.6 0.4 0.1 89.1 0.0 0.0 41.4 0.1 0.5 377.7 10.7 8.9 0.0 0.0 0.0 0.0 0.0 0.0 154.6 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.3 519.2 0.0 1.0 1.2 174.5 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.9 0.0 1.4 0.0 112.0 25.9 ARMC7 FLJ22160 ENSG00000125449 "Armadillo repeat containing 7" Q9H6L4 17 75109952-75130272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 39.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024229, HPA053076" Uncertain Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA024229: AB_2059152, HPA053076: AB_2682036" "unprognostic (1.35e-1)" "prognostic favorable (2.98e-4)" "unprognostic (7.73e-2)" "unprognostic (5.84e-2)" "unprognostic (4.15e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.84e-2)" "unprognostic (3.68e-1)" "unprognostic (4.28e-2)" "unprognostic (3.40e-2)" "unprognostic (4.86e-2)" "prognostic favorable (1.27e-4)" "unprognostic (1.93e-2)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.98e-2)" 7.4 6.7 7.3 5.8 7.5 4.1 7.4 12.7 9.0 7.7 7.7 12.4 9.6 7.0 4.8 11.2 6.6 4.7 8.8 7.6 7.7 39.5 13.2 12.3 7.0 7.3 7.1 5.2 7.0 6.6 7.0 5.8 7.6 11.8 6.9 2.7 8.9 6.4 5.5 12.0 11.9 4.0 7.0 14.0 11.4 7.3 7.9 8.2 9.9 3.9 6.4 8.7 9.3 7.9 15.2 30.2 8.9 8.5 7.0 4.3 9.4 8.3 9.0 15.9 14.3 25.3 14.7 9.0 10.8 7.7 8.7 12.4 14.6 6.1 7.6 8.7 23.2 17.5 13.4 15.9 15.5 13.5 16.1 5.6 11.4 10.0 5.8 7.7 14.6 14.5 15.8 17.6 5.3 21.7 25.9 14.8 4.5 32.8 22.6 14.6 18.0 16.8 35.6 27.4 8.3 11.9 15.6 15.7 18.6 15.2 18.4 12.9 11.3 16.1 14.9 6.4 13.1 14.7 5.5 12.7 7.2 9.6 11.8 31.7 13.7 28.5 18.0 9.9 15.8 13.4 12.9 15.1 12.7 10.0 9.8 14.9 18.6 15.7 7.9 11.1 20.8 11.7 7.3 7.5 12.7 9.0 7.6 7.7 7.3 7.1 7.6 7.0 7.9 7.9 6.6 12.8 8.8 1.3 10.4 4.6 2.8 5.8 2.2 6.0 6.0 5.1 2.5 7.2 5.2 22.0 0.0 14.1 10.1 28.6 35.2 8.7 6.2 4.6 3.0 9.0 6.0 1.7 3.0 9.4 8.3 4.1 8.6 5.1 10.8 4.4 14.3 4.6 15.2 0.0 2.9 9.8 6.1 7.5 3.3 12.2 5.3 9.7 12.4 1.9 13.9 3.3 11.3 2.5 1.8 11.3 27.1 3.8 6.4 4.8 15.8 15.4 7.2 3.4 19.7 2.2 4.6 3.8 5.9 4.4 4.5 4.9 8.7 6.6 12.4 3.8 ARRDC4 FLJ36045 ENSG00000140450 "Arrestin domain containing 4" Q8NCT1 15 97960703-97973833 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 105.7;Paneth cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 1.1;classical monocyte: 2.5;eosinophil: 1.5;intermediate monocyte: 1.7;myeloid DC: 1.1;neutrophil: 1.4" "Group enriched" "Detected in many" 8 "dendritic cells: 1.1;granulocytes: 1.5;monocytes: 2.5" "Cell line enhanced" "Detected in many" "BJ: 103.2;HSkMC: 55.8;hTCEpi: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039934, HPA042109" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Vesicles "HPA039934: , HPA042109: AB_10795606" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-3)" "unprognostic (4.49e-3)" "unprognostic (8.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.78e-1)" "unprognostic (7.65e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (2.02e-3)" "unprognostic (2.90e-2)" "unprognostic (1.65e-1)" "unprognostic (3.04e-2)" "unprognostic (6.77e-2)" 12.5 12.2 21.6 16.5 24.6 11.5 19.8 24.1 22.4 16.2 16.9 43.9 15.8 14.6 15.6 10.0 14.5 17.2 12.1 30.5 39.1 25.1 30.2 19.8 7.5 76.6 24.1 7.3 34.7 6.3 8.9 18.3 73.9 10.9 23.0 4.5 8.1 16.4 14.8 35.5 22.6 18.1 45.9 8.0 26.9 14.7 20.5 5.7 17.3 9.6 5.1 14.9 10.8 82.8 5.8 0.2 0.8 15.0 6.6 47.7 0.0 103.2 45.8 13.5 6.0 6.2 3.6 0.0 14.2 4.8 1.2 6.0 3.7 36.0 21.6 0.0 9.6 10.1 1.9 4.1 2.6 7.0 15.2 55.8 86.9 15.4 17.9 18.8 0.7 2.9 14.4 0.0 4.9 19.2 1.2 5.8 3.0 17.4 2.1 0.1 0.9 0.2 26.3 12.7 5.0 8.8 15.7 5.7 29.5 3.1 2.1 10.6 0.1 4.0 2.9 21.2 5.0 0.0 0.0 0.2 8.7 1.2 10.6 1.1 2.5 1.5 0.0 1.7 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.4 21.6 24.6 24.1 22.4 30.5 39.1 76.6 24.1 73.9 45.9 20.5 82.8 5.7 3.2 10.4 19.9 4.0 25.4 3.1 11.0 23.9 1.6 14.4 8.3 12.9 8.6 9.4 22.0 6.2 0.3 1.4 105.7 7.9 2.7 4.5 21.5 17.6 5.9 38.3 4.4 8.1 8.2 0.2 12.3 15.8 18.0 23.5 1.4 6.4 17.1 21.5 0.0 6.0 29.5 10.2 23.9 10.5 10.9 5.0 19.7 24.9 3.7 13.4 0.7 3.1 38.7 3.4 12.0 82.4 8.2 0.2 12.2 30.2 3.1 15.6 3.5 0.0 7.8 12.5 2.0 12.6 11.8 31.1 0.7 1.3 17.5 31.3 12.2 ARSD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.2;EFO-21: 24.5" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA004694: AB_1078221, HPA063835: AB_2685132" "unprognostic (3.92e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.21e-4)" "unprognostic (5.90e-3)" "unprognostic (6.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (4.09e-3)" "unprognostic (7.18e-2)" "unprognostic (3.93e-1)" "prognostic favorable (1.97e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (4.99e-2)" "unprognostic (2.11e-3)" 8.4 7.8 4.3 6.1 4.1 4.9 23.6 4.2 4.5 23.9 10.7 20.5 21.0 11.2 15.9 10.0 28.0 11.4 4.8 4.1 5.1 38.9 40.0 16.8 3.6 6.3 5.7 18.7 32.4 12.7 4.2 8.6 5.4 19.3 14.8 1.7 17.5 13.3 1.7 7.3 15.4 7.6 5.6 7.2 30.4 3.8 4.6 2.8 21.1 3.2 4.2 11.7 8.4 5.0 6.9 12.0 3.2 15.4 13.6 7.7 0.1 3.9 7.1 1.7 1.1 0.7 23.2 0.0 24.5 7.9 18.1 0.0 0.6 2.0 1.6 0.2 0.0 0.0 0.0 4.0 7.5 0.0 9.1 12.3 6.3 3.4 3.6 11.1 11.5 0.0 0.0 0.1 7.6 16.9 0.1 1.7 2.7 21.3 5.0 2.9 0.0 0.2 12.3 0.1 0.0 8.5 5.4 6.3 4.1 8.5 17.1 13.1 10.6 0.0 0.5 1.2 1.8 0.1 0.0 0.0 11.1 8.2 8.8 1.5 5.8 4.1 1.7 5.0 0.6 1.3 0.8 1.4 4.4 0.8 0.2 0.9 1.0 2.0 2.0 3.0 0.3 2.5 4.3 4.1 4.2 4.5 4.1 5.1 6.3 5.7 5.4 5.6 4.6 5.0 13.4 19.2 36.4 9.8 4.5 5.0 13.9 11.3 10.8 4.9 45.0 30.9 5.6 74.4 23.1 44.1 0.0 19.1 8.6 44.3 19.6 35.1 0.7 68.6 19.6 13.8 67.9 3.4 0.9 53.9 25.0 7.9 31.6 67.8 16.5 66.8 11.7 109.9 18.5 0.0 1.7 56.2 10.2 17.8 6.4 1.4 6.2 16.1 14.2 6.5 23.1 5.8 11.3 3.5 1.5 47.4 47.9 6.8 1.6 18.1 53.1 23.4 25.8 0.9 6.6 15.1 10.7 1.3 3.9 16.2 7.2 26.0 4.3 38.3 60.9 16.4 ASL ASAL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075800-66094697 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 396.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 294.6;Exocrine glandular cells: 218.6;Hepatocytes: 578.0;Paneth cells: 240.4;Proximal enterocytes: 259.9;Proximal tubular cells: 243.1" "Cancer enhanced" "Detected in all" "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol NA NA 12000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB003696: AB_425316, HPA016646: AB_1845096" "unprognostic (2.95e-2)" "prognostic unfavorable (4.05e-6)" "unprognostic (4.83e-1)" "unprognostic (4.18e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (7.25e-2)" "unprognostic (4.95e-2)" "unprognostic (2.07e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.40e-3)" 21.7 16.1 5.9 16.7 6.0 23.9 22.0 6.6 8.5 18.2 8.7 53.8 60.7 17.0 6.7 28.7 18.1 27.7 16.9 5.9 8.0 61.2 396.4 27.4 10.3 7.4 7.1 19.7 37.1 15.1 19.8 9.1 9.8 19.5 35.7 2.4 18.3 9.8 8.7 15.1 45.6 10.1 6.2 30.5 43.9 4.5 7.6 5.3 24.9 6.9 8.8 19.3 19.8 6.7 48.4 18.9 11.2 36.7 26.3 18.1 22.1 34.0 31.8 49.5 43.6 43.7 59.0 15.9 53.7 48.5 36.6 13.4 7.1 59.1 11.1 10.5 8.9 18.8 17.9 77.2 48.8 24.0 51.3 38.3 19.5 31.8 51.8 12.5 48.1 11.3 34.4 27.8 25.4 36.6 4.8 28.9 15.8 65.5 26.1 12.1 11.0 51.6 31.9 31.6 18.4 24.3 32.3 109.7 12.3 11.4 46.0 19.7 55.1 53.7 30.8 23.5 45.2 30.2 16.9 19.0 55.0 41.5 49.5 34.2 42.6 50.8 16.9 46.6 15.1 21.8 11.5 13.4 46.2 13.8 8.2 8.5 7.3 73.7 36.1 2.5 23.4 27.3 5.9 6.0 6.6 8.5 5.9 8.0 7.4 7.1 9.8 6.2 7.6 6.7 34.5 19.2 61.4 5.2 20.4 5.5 21.4 24.2 9.1 12.7 24.5 20.4 9.2 124.4 25.8 31.3 22.9 20.7 25.4 294.6 52.8 73.7 4.0 41.2 12.1 30.7 54.0 47.1 9.4 218.6 45.7 14.4 115.7 34.1 44.5 12.0 42.8 578.0 46.0 15.2 9.7 126.5 16.2 41.2 17.6 6.3 9.3 22.3 8.8 1.9 48.3 7.2 34.0 2.5 4.8 118.3 240.4 8.2 23.4 14.9 259.9 243.1 42.8 13.2 13.1 16.9 17.5 3.2 5.7 19.5 4.3 22.3 18.0 13.5 189.4 22.0 ATF4 "CREB-2, TAXREB67, TXREB" ENSG00000128272 "Activating transcription factor 4" P18848 22 39519695-39522683 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011596 Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite, Cytosol" "CAB011596: AB_725569" "unprognostic (2.51e-2)" "unprognostic (7.36e-2)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (4.45e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (4.43e-2)" "unprognostic (1.97e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.41e-1)" "prognostic unfavorable (9.77e-5)" "unprognostic (7.06e-2)" "unprognostic (9.78e-2)" "unprognostic (6.40e-2)" "unprognostic (1.95e-1)" 582.7 408.4 322.1 204.1 337.9 888.2 488.9 349.4 416.4 362.4 319.2 853.9 215.2 389.2 232.2 391.5 381.8 245.6 389.9 316.2 328.3 393.7 492.9 438.0 223.9 353.2 336.7 346.1 629.0 202.6 304.7 247.8 346.6 454.8 218.4 497.5 472.4 278.6 789.2 370.6 362.7 347.4 336.5 351.1 574.5 154.1 339.1 243.7 317.8 420.8 280.6 572.8 363.9 366.3 398.5 230.6 412.3 532.3 450.0 437.1 670.3 470.5 726.2 366.8 462.1 508.5 300.0 760.2 100.7 358.0 300.6 305.1 676.3 551.9 463.7 475.2 461.0 518.9 259.5 516.8 962.7 992.0 479.4 733.3 1172.0 654.3 973.2 658.2 365.8 825.3 560.4 790.7 288.6 241.8 599.2 713.8 354.8 828.1 288.3 612.0 268.5 793.5 491.0 328.0 605.3 254.3 214.8 559.3 1405.8 374.4 342.4 1191.5 290.4 221.5 645.9 250.8 323.8 1004.7 1100.7 888.7 244.9 497.5 506.3 46.5 36.9 24.8 20.0 31.6 26.4 37.9 27.6 26.5 44.3 28.7 28.6 26.6 17.8 26.8 34.9 27.0 31.6 28.8 322.1 337.9 349.4 416.4 316.2 328.3 353.2 336.7 346.6 336.5 339.1 366.3 201.0 169.9 176.0 19.2 181.8 443.9 344.3 171.2 205.5 120.5 286.8 211.5 167.9 143.0 148.7 44.1 93.8 140.1 156.9 357.9 66.5 200.9 20.9 154.2 122.8 229.9 266.7 140.4 19.2 765.1 309.0 198.0 184.5 191.7 223.0 119.0 146.7 190.9 112.7 69.0 16.6 371.4 101.7 174.3 348.4 21.1 185.1 215.7 238.3 22.5 239.5 94.7 92.7 16.6 34.7 396.0 335.7 206.9 223.7 378.5 265.0 85.8 92.3 311.3 335.2 306.5 279.0 72.3 61.5 155.3 335.7 218.4 175.5 115.0 284.5 401.1 ATG4B "APG4B, AUTL1, DKFZp586D1822, KIAA0943" ENSG00000168397 "Autophagy related 4B cysteine peptidase" Q9Y4P1 2 241637213-241673857 "Enzymes, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037195, HPA069803" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "CAB037195: AB_1078237, HPA069803: AB_2686200" "unprognostic (1.51e-1)" "unprognostic (8.80e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "unprognostic (2.67e-3)" "unprognostic (1.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (2.60e-1)" "unprognostic (6.63e-2)" "unprognostic (1.66e-1)" "prognostic favorable (9.64e-4)" 12.0 17.5 21.4 8.1 21.7 14.7 13.2 20.9 24.7 18.0 20.1 19.7 11.4 16.8 5.3 16.2 16.8 7.6 18.4 21.6 23.0 19.7 18.0 12.4 13.2 23.0 21.4 16.5 16.4 12.1 21.5 7.2 23.6 22.6 5.4 8.5 14.4 9.6 18.7 16.7 18.3 6.7 20.7 19.9 16.1 19.7 22.4 16.1 18.7 7.6 7.8 16.3 14.6 21.5 8.8 15.6 16.9 13.5 15.8 10.5 29.5 23.8 9.8 16.5 12.4 15.0 9.8 7.4 7.2 11.8 10.5 16.5 16.0 20.3 3.8 18.8 31.8 19.6 14.1 40.2 20.1 13.6 12.0 13.8 15.0 9.0 7.1 16.8 11.0 44.3 23.4 5.1 8.6 32.6 33.4 36.9 30.9 23.8 25.9 51.3 25.1 16.2 11.4 14.9 26.2 21.3 17.5 13.9 27.8 14.1 15.5 24.6 15.4 7.1 12.0 14.8 13.3 21.1 17.0 34.6 18.8 21.4 17.6 3.9 17.9 19.2 18.5 15.6 15.9 15.8 14.2 15.6 20.4 16.5 18.0 12.8 12.8 11.8 18.9 17.0 20.4 16.8 21.4 21.7 20.9 24.7 21.6 23.0 23.0 21.4 23.6 20.7 22.4 21.5 23.2 32.1 33.8 41.1 25.6 24.3 27.2 41.3 25.0 22.2 24.4 21.8 16.2 25.8 29.9 27.6 33.3 35.8 33.5 61.8 19.6 37.5 18.1 28.6 21.9 25.3 35.9 31.8 38.5 40.2 28.5 22.6 40.8 43.3 19.0 36.5 20.3 27.9 33.4 42.1 33.8 36.4 42.7 28.5 34.5 25.9 22.1 30.7 28.4 31.9 51.2 24.5 41.2 20.1 41.0 41.5 41.5 24.8 28.6 35.6 70.5 25.1 26.7 26.8 19.7 22.7 22.8 58.3 63.3 19.9 25.4 53.9 29.4 27.6 35.6 32.5 ATG4D "APG4-D, APG4D, AUTL4" ENSG00000130734 "Autophagy related 4D cysteine peptidase" Q86TL0 19 10543895-10553418 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 103.9;Proximal enterocytes: 109.3;Spermatocytes: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 57.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067683 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" "HPA067683: AB_2685886" "unprognostic (2.85e-1)" "prognostic favorable (3.18e-5)" "unprognostic (2.73e-1)" "unprognostic (3.67e-1)" "unprognostic (2.18e-1)" "unprognostic (1.15e-2)" "unprognostic (3.52e-2)" "unprognostic (1.23e-1)" "unprognostic (4.28e-2)" "unprognostic (7.30e-2)" "prognostic favorable (9.95e-4)" "unprognostic (1.52e-1)" "prognostic favorable (2.39e-7)" "prognostic favorable (5.03e-4)" "unprognostic (3.78e-2)" "unprognostic (2.29e-1)" "unprognostic (3.18e-3)" 7.3 15.6 4.2 7.3 4.7 33.2 7.4 8.3 8.6 9.4 8.2 22.3 21.8 8.1 1.6 27.3 7.6 3.9 23.2 4.5 4.0 20.8 13.2 10.6 8.3 5.2 4.7 9.5 16.3 10.7 16.6 4.9 5.3 14.0 5.2 2.5 16.6 4.4 36.9 24.6 23.2 2.1 3.1 17.0 13.7 24.5 5.4 12.0 13.4 10.8 4.6 9.7 15.0 6.1 13.8 8.7 11.7 16.5 2.1 1.8 9.9 9.2 7.8 11.1 12.2 14.9 4.3 9.2 16.2 0.9 8.6 20.8 7.3 6.8 1.4 10.4 23.5 23.1 22.3 8.2 7.4 9.4 22.1 1.8 14.2 9.8 3.4 2.8 3.3 18.1 17.8 19.8 3.6 21.9 27.6 57.8 18.9 6.1 29.0 20.0 8.2 15.1 6.4 17.8 45.3 17.8 12.6 22.6 11.3 2.1 14.0 21.6 6.4 16.8 11.0 34.7 20.4 19.2 15.4 10.8 14.4 18.0 19.5 1.6 0.8 3.7 1.1 1.0 1.5 1.0 1.3 1.2 0.6 0.4 1.2 1.7 0.2 1.3 0.4 4.2 2.2 0.8 4.2 4.7 8.3 8.6 4.5 4.0 5.2 4.7 5.3 3.1 5.4 6.1 6.3 9.6 6.6 9.1 14.4 30.5 19.8 14.9 24.5 14.9 14.1 10.2 0.5 14.3 8.1 1.8 14.6 27.9 38.7 103.9 13.7 16.1 83.6 9.6 5.5 5.3 22.2 43.6 8.4 16.5 6.7 8.2 26.5 10.1 7.0 10.9 6.1 11.9 13.4 28.6 9.1 38.5 20.3 15.0 12.1 16.3 8.7 10.0 12.4 4.7 15.7 11.8 22.6 4.5 8.4 20.5 72.4 4.5 17.6 21.6 109.3 25.4 5.2 20.1 13.1 9.1 14.2 100.7 21.2 33.4 31.3 36.5 19.6 10.6 33.2 36.4 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.1;gallbladder: 16.6;intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 136.4;Oligodendrocyte precursor cells: 293.0;Oligodendrocytes: 419.4;Undifferentiated cells: 90.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 13.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034574 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.1 0.0 4.1 5.0 9.0 0.0 0.4 8.8 6.4 1.0 0.1 44.5 24.7 0.0 12.3 6.2 0.4 16.6 0.0 4.3 5.0 0.1 0.0 0.0 0.0 10.6 7.8 0.0 2.9 0.0 0.0 0.0 9.9 0.0 45.7 0.0 1.8 0.7 0.0 7.1 21.0 1.5 5.8 0.0 4.8 0.3 8.0 5.0 0.0 0.0 2.9 1.5 2.5 17.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 9.0 8.8 6.4 4.3 5.0 10.6 7.8 9.9 5.8 8.0 17.1 0.1 0.0 0.0 42.7 0.6 0.4 0.1 12.9 0.0 0.0 0.1 0.0 1.2 21.5 15.1 1.8 0.0 0.0 0.0 136.4 0.0 23.6 0.2 0.2 0.0 0.3 13.2 0.0 4.0 20.3 0.1 0.0 10.7 0.3 0.0 0.0 0.0 0.3 0.1 0.0 3.9 55.4 4.1 0.0 1.2 0.6 0.0 0.1 1.8 1.9 1.6 0.0 0.0 293.0 419.4 16.4 64.7 0.0 0.4 0.1 24.1 0.0 16.0 0.0 0.0 0.0 0.6 0.0 0.1 2.9 0.9 0.5 0.3 0.0 90.7 6.5 ATP13A1 "ATP13A, CGI-152, FLJ31858, KIAA1825" ENSG00000105726 "ATPase 13A1" Q9HD20 19 19645198-19663676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031798, HPA049717" Approved Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA031798: AB_2674048, HPA049717: AB_2680858" "unprognostic (2.08e-1)" "unprognostic (4.92e-2)" "unprognostic (4.30e-2)" "unprognostic (7.29e-2)" "unprognostic (3.33e-1)" "unprognostic (4.40e-3)" "unprognostic (3.97e-3)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (2.60e-2)" "unprognostic (1.16e-2)" "unprognostic (9.43e-3)" "prognostic unfavorable (6.51e-4)" "unprognostic (2.26e-3)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.57e-1)" 12.9 17.0 7.3 21.8 6.5 16.1 13.9 5.4 8.6 17.1 12.3 15.6 18.6 16.2 8.0 15.6 15.0 14.0 9.7 7.4 7.9 12.8 12.9 14.0 21.4 7.9 6.5 20.8 21.1 23.4 18.1 12.9 6.9 15.1 13.0 8.8 17.7 12.6 12.8 16.2 22.2 11.6 6.1 26.4 16.7 15.8 7.6 15.9 20.2 5.8 17.5 13.9 14.4 9.0 32.8 45.2 24.3 52.8 38.2 25.3 66.1 28.9 40.1 24.5 24.9 43.5 54.3 44.9 48.6 34.4 14.0 17.8 37.2 37.0 13.4 16.5 77.6 24.6 48.7 34.5 39.3 46.8 70.1 36.7 34.2 26.5 31.8 27.1 17.9 32.1 43.0 97.5 24.7 53.9 31.8 33.7 44.5 40.6 54.7 25.0 17.4 100.9 25.8 44.7 33.4 56.7 26.8 42.6 30.0 11.4 26.9 50.6 28.7 51.5 7.7 59.2 35.3 78.8 50.6 26.8 36.0 59.6 39.5 0.0 3.5 3.5 2.8 5.6 3.1 2.2 3.3 3.1 6.5 1.9 2.1 2.7 0.1 1.4 8.6 5.0 2.9 2.4 7.3 6.5 5.4 8.6 7.4 7.9 7.9 6.5 6.9 6.1 7.6 9.0 11.3 9.6 5.8 12.1 22.7 5.9 7.4 8.2 9.6 12.0 13.0 8.5 5.5 11.5 9.0 14.7 18.8 20.3 12.5 28.5 1.9 19.1 10.3 11.5 9.8 9.0 18.6 11.1 11.2 18.4 18.2 10.2 31.6 13.6 5.7 16.2 10.8 13.2 20.0 5.0 11.0 22.9 12.2 12.2 9.5 5.1 14.0 18.3 7.2 7.5 13.6 12.6 8.2 9.0 11.0 15.6 22.4 9.8 50.4 11.9 28.6 6.6 12.8 10.8 6.6 9.2 11.4 14.7 14.6 12.6 6.1 15.3 13.9 20.2 22.2 6.4 ATP13A2 "CLN12, HSA9947, PARK9" ENSG00000159363 "ATPase cation transporting 13A2" Q9NQ11 1 16985958-17011928 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuronal ceroid lipofuscinosis, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.4" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037038, CAB037111, HPA050910, HPA054717" Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB037038: AB_1840715, CAB037111: AB_1840714, HPA050910: AB_2681269, HPA054717: AB_2682583" "unprognostic (3.81e-2)" "unprognostic (1.84e-2)" "unprognostic (5.61e-2)" "unprognostic (2.17e-2)" "unprognostic (1.66e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.33e-7)" "unprognostic (1.04e-1)" "unprognostic (9.71e-3)" "unprognostic (4.51e-1)" "unprognostic (9.85e-3)" "unprognostic (1.85e-1)" "unprognostic (5.75e-2)" "unprognostic (3.25e-2)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (6.84e-3)" 15.3 18.6 49.7 20.2 45.8 11.6 14.3 30.3 81.2 10.6 3.3 15.9 12.7 12.1 6.6 23.6 9.5 9.3 11.6 46.7 66.0 16.6 6.2 17.9 17.7 112.4 60.8 8.7 55.7 12.9 57.0 12.6 110.8 14.3 9.8 22.8 27.4 7.9 17.2 16.5 16.7 8.6 32.0 26.0 19.3 10.3 64.1 9.5 16.7 5.3 10.3 12.9 12.1 44.3 28.3 27.4 14.7 60.8 13.8 12.2 40.8 15.8 15.4 17.1 16.6 48.9 31.4 12.5 65.9 26.9 14.6 43.1 32.1 59.5 6.2 17.2 58.5 43.7 28.0 27.2 17.5 15.6 19.6 10.0 31.6 47.1 36.6 55.0 32.3 32.2 28.2 22.6 70.2 22.2 18.4 8.8 23.2 66.3 20.0 20.0 60.1 50.7 19.0 42.8 40.9 27.4 73.8 87.7 60.2 18.8 29.9 19.6 34.4 18.0 34.5 30.8 33.1 4.8 6.1 14.0 34.6 85.2 30.3 0.0 1.6 0.3 2.6 3.7 2.9 1.3 2.1 2.2 0.4 3.1 1.0 1.5 0.5 2.7 3.6 20.6 1.8 1.4 49.7 45.8 30.3 81.2 46.7 66.0 112.4 60.8 110.8 32.0 64.1 44.3 18.9 0.0 2.2 14.4 8.3 6.5 6.9 5.7 6.2 35.9 16.9 11.3 3.6 7.2 6.8 7.3 35.5 5.8 33.4 44.6 5.9 15.1 1.4 6.7 3.8 14.4 7.7 4.2 53.1 25.1 33.6 6.0 18.8 19.0 8.9 20.5 6.1 3.7 10.4 47.1 61.8 15.0 0.0 17.3 2.8 1.7 5.3 10.1 5.4 11.2 6.1 34.0 8.2 20.1 18.1 57.0 49.0 6.4 5.4 12.3 18.2 5.3 4.3 38.4 0.0 4.6 5.7 13.6 16.4 11.6 5.3 9.3 11.1 4.8 21.7 12.8 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.4;skin 1: 26.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 56.2;Club cells: 50.0;Intestinal goblet cells: 82.3;Oligodendrocyte precursor cells: 58.8;Respiratory ciliated cells: 78.2;Undifferentiated cells: 77.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 24.5;OE19: 44.4;RT4: 19.3;SK-BR-3: 33.0;T-47d: 11.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA052262: AB_2681776, HPA075812: AB_2686765" "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favorable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.0 0.0 1.4 2.4 1.4 11.0 2.5 0.5 1.3 6.4 0.5 30.1 27.3 1.0 0.1 4.7 6.8 4.6 0.0 1.3 1.1 1.8 0.1 10.5 0.0 1.0 0.9 0.0 0.7 3.3 1.0 0.9 1.0 12.5 37.4 0.9 19.6 0.2 0.1 26.0 20.3 0.6 0.6 0.4 5.9 0.4 1.1 0.0 8.9 0.0 0.5 4.0 4.6 0.8 6.2 0.4 0.9 0.1 0.0 0.0 6.4 0.2 0.0 0.0 0.0 5.8 5.2 0.0 0.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.5 0.0 0.0 0.0 44.4 0.1 0.0 0.0 0.2 0.0 19.3 4.9 0.0 0.0 33.0 0.2 0.9 11.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 1.4 0.5 1.3 1.3 1.1 1.0 0.9 1.0 0.6 1.1 0.8 0.0 32.1 56.2 4.2 0.0 0.6 14.3 39.9 0.6 1.3 20.8 3.2 0.8 5.7 50.0 0.0 0.0 2.0 0.1 44.4 0.0 9.0 3.2 26.8 2.5 0.7 34.2 0.0 8.3 2.5 2.4 0.5 22.4 28.0 8.9 0.0 0.0 0.1 0.3 0.0 1.8 82.3 8.2 0.0 1.2 1.9 0.0 0.6 1.8 1.0 0.0 1.9 0.0 58.8 2.4 4.7 29.2 0.0 0.0 13.8 10.2 1.8 78.2 5.2 0.0 0.1 1.8 0.8 1.0 1.5 1.1 24.1 0.9 0.2 77.1 9.9 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 279.7;Intestinal goblet cells: 180.5;Paneth cells: 116.7;Undifferentiated cells: 185.7;Urothelial cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 90.2;RT4: 168.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 9.1 5.4 1.3 8.5 2.0 1.2 9.5 3.6 3.9 16.3 3.0 76.2 30.3 5.9 3.5 14.8 10.6 18.0 4.4 1.7 1.1 6.6 7.7 8.3 2.2 2.1 1.1 2.1 23.3 9.7 2.7 6.9 2.0 17.6 61.7 0.6 20.6 11.5 1.9 8.4 38.2 8.3 1.0 4.6 46.1 0.6 1.9 1.5 22.0 1.8 3.6 30.0 13.0 3.0 32.0 10.7 0.1 0.6 10.5 19.2 11.9 62.6 63.6 67.4 40.4 8.0 24.3 1.5 19.3 90.2 22.3 44.9 0.2 13.9 64.3 0.2 1.1 0.2 2.6 2.5 2.2 0.4 0.6 2.9 12.6 20.8 34.0 39.5 33.0 0.3 0.3 0.7 34.1 15.6 0.1 0.3 0.3 35.5 3.3 0.3 0.2 0.0 7.9 168.1 0.8 0.7 1.3 32.5 0.1 0.5 10.3 0.6 35.3 48.3 2.0 7.7 14.2 0.4 0.4 0.5 1.1 0.4 2.8 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.0 0.2 0.1 0.0 0.0 1.3 2.0 3.6 3.9 1.7 1.1 2.1 1.1 2.0 1.0 1.9 3.0 25.9 19.2 27.0 11.1 4.1 7.8 66.7 20.6 10.2 0.7 28.4 10.4 5.4 27.1 48.9 40.5 0.0 25.6 0.6 279.7 0.0 27.0 2.8 26.3 4.0 30.8 68.4 0.4 61.2 53.1 2.7 7.1 98.4 40.1 4.5 0.9 33.2 19.1 2.4 6.7 11.7 180.5 22.4 2.8 4.0 0.4 0.3 1.0 7.2 37.5 0.9 0.1 0.0 20.6 10.7 38.5 116.7 0.0 0.9 70.8 58.2 0.2 44.7 1.2 13.1 2.8 20.7 0.3 1.5 28.0 16.3 10.9 1.7 2.3 185.7 119.2 B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 196.4;Intestinal goblet cells: 47.4;Paneth cells: 72.5;Proximal enterocytes: 94.1;Undifferentiated cells: 57.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 23.5;RPTEC TERT1: 27.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.6" "HPA054092, HPA054684" Approved "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" 0.0 0.3 2.5 0.9 8.6 0.0 2.6 0.7 3.7 2.2 1.9 22.4 27.3 0.7 1.3 1.6 1.3 5.5 0.0 2.4 4.6 0.2 0.1 0.1 0.0 2.0 2.1 0.3 3.3 0.0 1.8 0.0 1.3 0.4 37.4 0.8 4.5 0.1 0.0 0.8 33.7 0.8 1.3 0.0 5.0 0.4 6.9 1.0 1.2 0.3 2.0 1.3 2.3 0.7 0.0 0.9 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 23.5 0.0 0.2 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 6.3 0.2 0.6 0.0 2.7 0.1 27.1 1.7 4.6 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.7 0.2 1.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 8.6 0.7 3.7 2.4 4.6 2.0 2.1 1.3 1.3 6.9 0.7 0.1 0.0 0.0 6.5 0.3 0.0 0.5 0.1 0.0 7.4 8.0 8.1 2.2 10.0 5.3 5.5 0.0 0.0 0.2 196.4 0.0 7.5 0.4 0.2 5.9 0.4 28.9 0.0 3.6 4.7 0.0 0.2 13.3 0.2 4.5 0.8 0.0 0.0 0.0 0.0 4.8 47.4 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 1.4 0.0 11.1 1.0 9.2 72.5 0.0 0.0 0.6 94.1 0.1 1.5 0.2 0.0 0.1 0.4 0.1 1.7 0.5 0.0 0.0 0.5 0.0 57.7 9.7 B3GNT3 "B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3" ENSG00000179913 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" Q9Y2A9 19 17794828-17813576 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.0;salivary gland: 31.4;stomach 1: 43.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 65.8;Cytotrophoblasts: 78.9;Distal enterocytes: 108.4;Paneth cells: 67.4;Proximal enterocytes: 50.5;Syncytiotrophoblasts: 68.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 44.2;BEWO: 40.9;CAPAN-2: 112.5;OE19: 102.1;RT4: 41.3;SK-BR-3: 38.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024298 Enhanced "Intracellular and membrane" NA NA 74000 "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA024298: AB_1845236" "unprognostic (1.10e-1)" "unprognostic (5.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.84e-3)" "unprognostic (1.10e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (3.26e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (7.38e-2)" "unprognostic (1.26e-1)" "unprognostic (7.10e-2)" "unprognostic (2.57e-2)" 0.3 0.1 0.3 5.7 0.1 0.2 3.4 0.7 0.4 4.4 0.3 44.0 32.6 0.4 0.0 21.7 1.0 23.8 0.0 0.3 0.3 3.8 2.4 0.5 0.5 0.3 0.2 0.1 3.9 0.5 0.0 12.6 0.3 2.2 40.5 0.0 31.4 3.2 0.0 2.7 29.5 1.7 0.0 0.1 43.2 0.1 0.1 0.2 0.3 0.0 4.7 18.5 8.1 0.5 44.2 12.5 0.0 0.2 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.7 112.5 0.0 28.9 0.0 0.1 4.2 0.0 12.9 0.0 0.0 0.2 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.2 0.1 0.4 102.1 19.2 0.2 0.0 1.2 23.9 41.3 0.0 0.1 0.0 38.4 0.0 0.0 1.7 0.2 0.1 0.3 3.3 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.7 0.4 0.3 0.3 0.3 0.2 0.3 0.0 0.1 0.5 0.1 0.0 2.3 0.0 0.2 0.1 3.6 5.1 0.0 0.0 7.1 6.2 0.4 65.8 17.1 16.5 0.0 78.9 0.5 108.4 1.9 17.9 0.0 3.8 0.8 2.3 16.3 0.0 0.1 28.4 7.5 0.7 19.9 7.7 5.7 0.0 0.7 0.2 6.0 0.0 0.2 40.7 6.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 33.2 67.4 0.0 0.0 7.8 50.5 3.5 7.7 0.0 0.0 0.0 0.9 0.2 0.3 0.2 0.0 68.3 0.2 0.5 28.4 39.6 B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 151.2;Distal enterocytes: 150.4;Squamous epithelial cells: 169.9;Syncytiotrophoblasts: 157.9;Urothelial cells: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Cell line enhanced" "Detected in many" "GAMG: 82.4;HBEC3-KT: 70.3;hTCEpi: 83.5" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" 11.9 2.4 3.3 13.7 3.5 76.5 5.5 2.3 3.2 6.0 0.9 22.6 38.2 5.1 9.1 37.5 9.6 21.3 3.5 3.7 4.0 3.8 3.3 15.0 1.1 5.6 3.8 4.6 7.5 3.5 5.7 13.9 4.6 7.9 19.6 1.2 10.1 3.3 7.4 10.3 42.0 6.7 4.3 1.6 11.3 7.3 3.5 7.6 5.2 4.5 5.3 24.2 13.8 5.5 46.2 4.4 23.8 14.7 19.5 57.0 21.5 0.7 1.1 4.6 3.8 9.0 23.6 0.0 2.7 0.1 82.4 20.6 24.7 70.3 3.9 0.1 15.3 2.4 1.9 0.0 24.8 23.4 10.9 27.0 83.5 3.7 62.1 6.2 43.4 0.1 26.6 0.1 38.1 0.0 0.1 7.6 10.1 26.9 38.5 7.3 12.0 0.1 14.4 12.7 1.0 22.6 12.7 0.1 5.3 10.6 0.0 28.0 64.6 1.1 9.0 1.4 11.0 0.0 0.0 0.0 8.8 54.1 23.8 0.0 1.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.2 0.3 3.3 3.5 2.3 3.2 3.7 4.0 5.6 3.8 4.6 4.3 3.5 5.5 151.2 6.4 17.5 2.3 1.2 65.1 70.2 35.8 101.3 10.0 18.4 10.4 2.2 21.5 40.5 5.5 22.9 31.0 1.9 150.4 1.9 18.0 13.4 58.0 13.1 26.3 38.2 6.3 1.8 11.8 10.7 9.2 70.3 55.3 14.0 2.4 2.2 0.6 29.6 3.3 1.5 88.2 34.6 15.6 123.2 26.5 1.5 76.8 12.4 80.6 9.4 3.1 0.0 4.5 0.8 35.7 126.4 0.4 1.4 43.1 74.9 4.8 118.5 13.1 0.0 23.6 5.4 7.9 0.8 169.9 84.8 157.9 4.3 0.2 36.2 144.4 B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 272.8;Intestinal goblet cells: 145.2;Paneth cells: 126.4;Undifferentiated cells: 354.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.5;HEL: 15.6;THP-1: 14.0;WM-115: 23.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 3600000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" 3.1 12.9 5.9 2.8 5.1 14.2 3.8 4.0 5.8 2.5 4.6 56.2 25.2 1.9 6.8 2.9 4.6 14.0 4.7 5.6 6.5 2.2 1.2 15.3 1.6 6.0 7.0 16.7 25.4 14.3 8.8 5.4 5.3 3.2 71.2 2.1 7.5 4.4 0.4 5.0 28.4 2.3 4.3 5.1 35.6 1.3 7.3 2.4 8.4 0.3 1.5 3.7 0.6 5.4 0.7 2.8 0.3 0.6 0.1 0.2 1.0 0.2 1.1 0.1 0.1 1.4 19.5 2.2 5.8 0.3 0.2 5.1 0.2 0.0 0.1 0.3 0.5 15.6 0.5 0.9 0.1 0.1 0.8 0.1 1.4 0.2 0.3 1.1 0.2 0.4 0.5 0.4 0.1 0.9 0.2 0.7 6.3 7.7 3.3 0.3 0.1 0.4 0.6 1.7 0.5 0.8 0.3 1.7 0.7 6.9 0.6 14.0 0.2 0.4 0.4 0.2 0.2 2.3 0.9 0.7 0.3 0.2 23.7 0.7 0.1 0.7 2.9 0.5 0.5 9.9 0.1 0.4 6.5 7.0 0.1 0.7 0.2 32.1 0.6 3.1 0.2 1.0 5.9 5.1 4.0 5.8 5.6 6.5 6.0 7.0 5.3 4.3 7.3 5.4 0.9 41.7 30.2 0.3 8.7 2.3 1.7 8.7 0.0 0.4 5.2 2.5 1.1 95.8 29.7 1.8 2.1 0.6 61.7 272.8 0.0 16.1 0.4 13.3 2.2 4.7 103.0 0.4 0.5 84.3 64.9 2.3 51.5 18.5 9.5 17.3 3.3 0.2 11.2 0.0 0.4 145.2 18.3 10.1 38.6 1.2 1.5 9.7 3.6 0.0 2.9 0.5 10.3 55.3 0.2 69.8 126.4 8.2 5.5 11.6 93.2 0.4 82.2 1.8 0.0 0.5 2.3 0.9 1.4 0.0 2.7 2.1 10.0 0.4 354.6 16.2 BAD "BBC2, BCL2L8" ENSG00000002330 "BCL2 associated agonist of cell death" Q92934 11 64269830-64284704 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004205, HPA028185, HPA062105" Approved Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB004205: AB_626717, HPA028185: AB_10603445, HPA062105: AB_2684684" "unprognostic (1.47e-1)" "unprognostic (3.08e-2)" "unprognostic (1.17e-1)" "unprognostic (8.24e-3)" "unprognostic (2.60e-1)" "unprognostic (6.73e-2)" "unprognostic (1.24e-3)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (8.26e-2)" "unprognostic (9.04e-2)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (7.95e-2)" 60.8 85.1 94.0 13.2 91.1 23.3 58.8 89.0 133.1 64.9 86.6 81.7 26.5 64.8 12.7 72.9 58.8 15.5 118.0 93.1 87.8 87.6 96.1 58.7 14.7 93.4 92.7 55.2 53.7 35.6 55.3 21.7 89.4 79.7 15.1 17.2 57.7 27.6 50.7 70.6 44.7 14.0 89.9 45.0 87.1 55.1 98.9 17.2 75.8 15.1 12.4 65.9 57.7 92.7 95.0 85.1 25.2 38.3 30.0 36.4 36.9 38.2 45.9 60.0 47.5 54.8 53.1 19.5 67.7 37.4 46.9 49.9 16.8 62.7 11.9 77.6 58.7 24.9 81.4 26.1 45.9 20.7 45.0 35.3 53.7 45.8 28.3 45.9 37.5 44.1 10.1 42.9 26.6 94.7 49.8 49.7 9.8 27.7 109.6 46.7 13.8 57.9 36.8 44.3 51.2 67.1 39.2 46.8 49.9 9.6 70.5 32.0 30.3 72.8 48.1 112.8 43.8 79.6 64.0 21.3 59.2 15.6 40.6 88.0 69.7 102.3 52.9 56.7 54.7 58.6 55.4 51.9 50.5 57.5 39.8 40.9 92.4 59.5 55.3 94.0 71.8 51.4 94.0 91.1 89.0 133.1 93.1 87.8 93.4 92.7 89.4 89.9 98.9 92.7 56.3 32.1 45.1 7.8 32.9 103.1 54.1 170.2 51.2 67.7 76.7 74.8 51.6 70.1 66.4 53.3 18.8 162.5 32.4 214.4 137.0 101.2 43.5 71.5 64.8 56.8 104.1 69.2 10.4 109.9 197.8 75.3 53.0 45.4 24.1 58.2 62.4 51.0 73.8 47.1 7.5 141.8 89.5 24.1 72.6 93.3 74.3 32.9 110.3 2.8 52.4 95.9 36.0 4.0 8.9 120.7 210.0 85.4 33.2 62.1 138.1 152.8 83.2 52.0 59.2 36.2 72.6 69.5 25.0 57.7 119.1 255.0 36.0 57.8 117.1 63.4 BAHD1 KIAA0945 ENSG00000140320 "Bromo adjacent homology domain containing 1" Q8TBE0 15 40439721-40468236 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041196 Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA041196: AB_10803999" "prognostic unfavorable (1.55e-4)" "unprognostic (4.08e-1)" "unprognostic (3.00e-2)" "unprognostic (1.56e-2)" "unprognostic (1.35e-2)" "unprognostic (1.04e-1)" "unprognostic (7.19e-2)" "unprognostic (1.12e-2)" "unprognostic (2.06e-2)" "unprognostic (2.00e-2)" "unprognostic (3.49e-3)" "unprognostic (4.81e-2)" "prognostic favorable (1.29e-10)" "unprognostic (4.95e-2)" "unprognostic (1.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" 9.6 21.9 10.8 8.0 11.5 8.1 9.2 8.6 10.5 11.0 9.9 12.3 9.1 12.5 10.2 12.0 13.6 6.3 14.3 11.9 9.8 14.2 11.6 12.5 9.8 10.3 9.5 21.4 13.8 13.0 13.3 8.7 9.4 10.3 5.8 5.2 12.6 10.2 12.6 11.0 12.0 7.2 9.1 12.6 12.7 18.6 10.9 11.6 16.5 7.6 9.1 12.3 9.1 10.1 16.9 8.5 14.7 24.5 11.7 9.1 32.0 13.3 9.5 14.4 14.0 23.1 7.9 12.5 17.6 12.0 17.6 32.6 24.2 10.1 8.0 24.2 15.2 32.9 13.2 11.5 11.1 14.4 24.0 12.0 10.2 8.8 8.7 12.8 12.5 15.8 32.8 10.4 8.6 16.0 16.2 21.8 14.6 19.7 15.6 27.3 16.6 10.4 15.9 19.7 23.0 13.9 8.2 42.8 9.7 9.1 34.4 23.1 14.8 15.6 17.4 22.4 14.1 15.5 18.4 14.2 16.3 22.1 10.7 0.6 0.3 1.4 1.3 0.6 0.6 0.5 0.9 0.7 0.3 0.7 1.2 1.0 0.3 1.4 1.2 0.6 0.3 0.4 10.8 11.5 8.6 10.5 11.9 9.8 10.3 9.5 9.4 9.1 10.9 10.1 9.7 19.2 7.0 7.8 4.9 8.3 3.7 4.1 6.8 3.9 11.4 9.4 11.7 5.7 7.7 11.0 2.1 5.5 5.6 20.7 1.9 5.4 1.0 6.1 4.9 8.4 7.8 2.5 10.3 7.4 7.3 4.7 2.0 8.4 8.9 5.6 9.7 12.0 5.7 16.8 8.1 7.4 2.0 12.0 4.6 2.7 10.2 5.4 0.0 7.5 6.7 5.2 10.3 9.0 8.9 6.7 8.9 5.7 1.6 5.3 11.6 5.0 5.0 4.7 6.6 6.1 5.5 6.3 10.9 6.9 7.7 4.1 5.8 7.6 8.0 4.9 BAK1 "BAK, BCL2L7, CDN1" ENSG00000030110 "BCL2 antagonist/killer 1" Q16611 6 33572547-33580293 "Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.4;Proximal enterocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005029 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB005029: AB_562051" "unprognostic (3.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (5.67e-2)" "unprognostic (6.58e-3)" "prognostic unfavorable (4.52e-4)" "prognostic unfavorable (5.64e-4)" "unprognostic (2.36e-1)" "unprognostic (1.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (6.07e-2)" "unprognostic (3.36e-2)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" 9.4 29.6 10.4 20.7 10.6 27.7 7.5 10.5 13.0 10.4 12.2 32.4 47.0 10.1 9.1 34.0 7.9 10.6 23.2 10.3 9.8 23.9 11.5 13.7 22.0 11.8 10.9 7.2 12.8 13.5 12.0 11.1 11.2 11.2 24.9 3.7 11.9 9.1 18.8 18.7 37.1 13.5 11.0 30.5 21.9 7.8 11.7 19.2 7.7 18.1 23.4 21.8 12.0 10.4 37.6 20.4 21.3 32.2 14.3 14.0 27.1 19.1 15.3 53.7 41.8 42.2 28.7 32.5 32.6 28.1 24.8 38.3 41.0 77.7 23.6 37.7 43.6 20.6 18.8 34.4 36.6 44.5 32.3 23.0 60.7 45.1 52.6 15.7 29.4 28.7 18.9 28.6 20.1 55.0 38.8 29.7 23.7 26.4 50.0 37.0 20.5 59.9 45.6 30.6 26.3 19.6 24.4 77.3 37.1 26.6 25.4 74.5 28.2 28.3 30.0 18.5 24.9 75.4 100.4 27.5 9.6 52.6 31.7 63.5 45.2 85.1 34.7 64.8 39.5 25.3 32.1 34.7 42.8 18.4 17.6 23.2 30.6 22.4 57.3 15.0 56.1 53.2 10.4 10.6 10.5 13.0 10.3 9.8 11.8 10.9 11.2 11.0 11.7 10.4 8.6 3.2 3.4 3.9 24.6 27.1 11.6 15.5 14.2 6.6 10.7 8.3 6.4 11.5 8.0 3.7 8.4 16.3 22.1 75.4 13.7 20.5 4.7 7.2 8.9 10.1 22.1 6.1 4.5 18.7 41.8 7.5 17.9 10.0 11.4 11.1 10.0 6.3 30.2 5.0 3.6 32.5 14.2 21.9 30.2 1.7 7.8 16.9 21.4 2.8 25.8 4.7 12.3 1.0 2.7 27.7 47.9 11.7 54.5 10.4 79.6 9.6 5.6 6.9 13.1 5.6 11.8 0.3 1.0 19.1 21.6 9.9 24.6 25.2 40.6 20.1 BATF2 MGC20410 ENSG00000168062 "Basic leucine zipper ATF-like transcription factor 2" Q8N1L9 11 64987945-64997018 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 21.2;Intestinal goblet cells: 8.5;Proximal enterocytes: 7.9;Undifferentiated cells: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.1;intermediate monocyte: 5.3;neutrophil: 7.3;non-classical monocyte: 2.8" "Group enriched" "Detected in many" 6 "granulocytes: 7.3;monocytes: 5.3" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 13.1;BJ hTERT+ SV40 Large T+ RasG12V: 20.0;GAMG: 19.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA062496 Approved Approved Nucleoli NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA062496: AB_2684783" "unprognostic (5.29e-2)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (4.59e-2)" "unprognostic (2.31e-2)" "unprognostic (6.11e-2)" "unprognostic (5.08e-2)" "unprognostic (6.92e-3)" "unprognostic (1.03e-1)" "prognostic favorable (9.39e-5)" "prognostic unfavorable (2.12e-4)" "unprognostic (1.28e-1)" "unprognostic (9.09e-3)" "unprognostic (2.34e-3)" "unprognostic (3.17e-2)" "unprognostic (3.82e-2)" "unprognostic (1.12e-2)" 2.2 4.4 2.7 8.7 2.8 0.5 1.4 2.4 2.9 1.7 2.8 8.6 9.3 1.2 0.7 1.0 2.6 3.9 3.0 2.5 2.6 5.7 4.7 7.0 3.2 4.1 2.7 3.1 9.2 0.9 2.3 2.8 4.0 2.8 6.2 0.5 13.4 4.4 4.9 0.4 6.5 2.7 4.0 13.5 4.5 0.7 3.0 1.6 2.0 2.7 1.2 4.6 1.0 2.6 1.5 1.0 0.2 0.0 0.1 0.8 0.0 0.5 6.5 13.1 20.0 1.9 5.8 0.1 2.7 1.0 19.5 0.1 0.0 1.7 0.9 0.2 0.4 1.8 0.0 5.3 4.8 0.0 1.1 0.4 0.4 1.7 2.2 0.5 3.2 0.1 4.3 0.1 0.3 0.4 0.0 0.1 0.5 0.0 0.6 0.0 1.3 0.6 1.6 0.1 0.1 0.0 0.8 0.3 6.9 0.1 0.5 1.0 2.4 0.7 0.7 1.1 0.0 0.1 0.2 0.4 1.1 0.5 0.6 0.0 2.1 1.0 0.0 5.3 0.0 1.0 0.0 0.0 0.2 0.3 0.0 0.0 7.3 0.1 2.8 0.0 0.0 0.8 2.7 2.8 2.4 2.9 2.5 2.6 4.1 2.7 4.0 4.0 3.0 2.6 3.7 3.2 2.0 1.0 1.3 0.0 0.5 1.8 0.0 0.2 1.2 0.5 0.6 4.3 2.6 1.8 0.0 0.0 0.0 21.2 1.9 4.8 0.8 0.4 1.2 2.7 2.4 0.0 0.2 6.6 0.3 1.8 2.6 0.1 0.0 0.1 5.0 0.9 4.7 0.0 0.1 8.5 0.0 3.5 0.3 2.4 0.0 1.0 0.0 1.0 1.0 0.9 0.0 1.0 0.1 4.9 7.6 0.7 0.0 0.2 7.9 4.1 3.5 0.2 0.0 1.7 1.7 0.1 0.6 0.0 0.0 0.0 0.1 1.1 8.4 2.4 BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282" Approved Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: AB_2677929" "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavorable (9.11e-5)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favorable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" 34.7 22.3 3.5 4.2 5.8 0.0 27.9 16.9 6.6 37.7 6.3 34.4 15.8 39.2 2.6 22.5 25.3 9.4 47.1 2.3 7.9 47.3 34.2 38.8 2.1 3.9 1.9 19.7 32.4 5.9 29.5 14.1 2.3 25.6 3.5 1.3 25.5 5.7 93.8 18.2 33.1 3.8 0.0 33.7 44.6 34.3 4.2 0.9 26.8 6.8 1.1 24.9 26.2 15.8 21.8 36.8 17.5 6.0 6.7 6.3 34.1 29.5 17.1 20.9 16.4 46.5 32.1 1.9 38.2 33.3 23.6 18.2 6.1 34.0 6.0 0.1 20.0 0.0 23.7 37.2 16.7 0.1 15.1 19.1 16.3 25.3 12.5 12.3 57.9 0.0 20.0 1.0 12.6 48.9 0.1 1.3 23.4 16.1 24.0 0.8 7.9 8.2 19.1 27.9 21.4 31.5 28.7 6.6 11.2 8.4 15.0 5.4 53.6 34.4 29.5 8.8 44.2 8.0 4.7 0.7 22.2 0.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 16.9 6.6 2.3 7.9 3.9 1.9 2.3 0.0 4.2 15.8 30.1 22.4 6.9 9.4 1.2 28.0 59.7 36.8 12.0 26.5 20.3 14.4 22.9 31.5 21.8 22.0 6.2 46.8 0.7 75.7 27.4 51.9 19.0 13.7 27.9 49.2 34.8 0.0 13.1 61.8 25.7 21.1 71.9 22.5 8.9 15.0 46.8 21.0 6.0 13.5 11.7 42.1 12.2 1.4 6.3 26.8 16.4 2.1 32.0 10.3 0.6 12.9 0.0 19.1 31.2 68.5 59.6 33.4 1.4 58.4 57.4 38.9 13.1 6.8 19.7 8.5 38.5 20.6 17.1 12.5 17.6 36.1 2.2 10.9 33.7 62.7 BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 324.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 44.2;U-937: 75.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030947, HPA058709" Enhanced Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA030947: AB_10669548, HPA058709: AB_2683797" "unprognostic (2.72e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.13e-1)" "unprognostic (3.93e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.86e-7)" "unprognostic (2.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.53e-2)" "unprognostic (5.17e-3)" "unprognostic (5.85e-3)" "prognostic favorable (7.12e-8)" "unprognostic (5.62e-2)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (1.02e-1)" 9.6 6.8 14.4 4.1 17.9 7.3 9.7 18.4 19.8 6.8 30.8 45.1 17.4 6.3 3.9 48.0 9.7 3.8 52.4 16.5 14.3 19.2 324.0 5.2 3.9 14.3 13.8 8.2 7.0 15.5 12.6 0.3 14.4 16.2 19.8 9.3 25.3 4.1 21.5 30.4 28.1 2.2 12.9 7.9 16.6 4.5 16.3 6.1 17.7 22.8 7.1 9.9 14.7 14.2 23.7 2.9 1.2 11.3 1.9 0.1 0.0 2.8 2.2 11.4 6.3 20.5 7.5 0.2 33.0 0.7 0.9 10.3 10.0 5.4 4.2 0.3 0.0 12.0 8.3 7.0 8.3 27.0 12.3 3.4 6.0 4.4 9.4 1.2 2.8 13.7 0.0 8.4 0.2 40.9 20.5 18.8 8.2 44.2 4.2 19.6 4.1 31.5 12.3 9.9 20.1 8.8 8.2 1.1 4.5 0.5 26.3 22.7 0.3 0.7 3.9 0.1 21.6 10.4 20.5 0.3 0.7 75.8 1.5 2.9 1.3 0.6 4.6 0.2 6.4 5.1 5.1 4.2 3.5 4.6 7.6 4.7 0.0 4.5 0.2 3.8 3.7 3.4 14.4 17.9 18.4 19.8 16.5 14.3 14.3 13.8 14.4 12.9 16.3 14.2 0.4 3.2 9.4 27.7 7.0 9.3 8.5 10.0 16.5 21.3 20.3 14.7 36.7 17.2 13.8 12.9 20.9 2.0 7.1 68.9 52.8 6.6 9.5 34.1 3.6 2.2 27.2 6.7 60.5 5.6 5.1 2.8 17.3 16.5 1.3 6.6 5.0 112.3 8.9 18.5 58.0 43.2 10.2 5.4 8.5 13.9 5.6 3.5 16.0 8.4 1.0 17.5 11.3 27.2 12.5 3.0 36.4 4.1 5.4 6.5 62.8 30.2 48.0 33.6 0.0 2.4 3.7 16.8 4.9 36.3 10.9 1.9 8.5 10.0 68.7 13.1 BEST4 VMD2L2 ENSG00000142959 "Bestrophin 4" Q8NFU0 1 44783585-44788170 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 16.4;fallopian tube: 8.3;intestine: 27.4" "Cell type enriched" "Detected in some" 25 "Paneth cells: 1290.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;U-698: 1.8" "Low region specificity" "Detected in many" HPA058564 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA058564: AB_2683759" "unprognostic (5.76e-2)" "unprognostic (1.22e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-2)" "unprognostic (6.51e-3)" "unprognostic (1.09e-1)" "unprognostic (8.39e-2)" "unprognostic (1.45e-3)" "unprognostic (1.04e-1)" "unprognostic (8.97e-2)" "unprognostic (5.72e-2)" "unprognostic (1.29e-1)" "unprognostic (2.69e-5)" "unprognostic (1.43e-1)" "unprognostic (3.72e-1)" "unprognostic (1.28e-1)" "unprognostic (4.13e-3)" 0.2 1.9 1.2 0.7 1.1 0.7 0.5 2.2 1.3 1.6 16.4 27.4 9.1 0.7 3.0 0.2 8.3 0.2 0.3 0.8 1.7 0.5 0.6 1.9 0.6 1.9 3.3 0.5 0.3 0.3 2.7 0.2 1.5 0.4 16.0 1.1 0.3 0.5 0.4 2.2 8.1 0.5 1.3 0.5 0.4 0.7 1.6 0.5 0.6 0.1 0.4 0.3 0.2 1.0 0.0 0.2 0.3 0.4 0.1 0.1 1.1 0.2 0.1 0.1 0.0 0.1 0.5 0.1 0.5 0.1 0.3 0.5 0.1 0.0 0.1 0.3 0.2 0.0 0.8 2.5 0.1 0.0 0.3 0.2 0.3 0.1 0.2 0.6 0.3 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.8 0.3 0.1 0.1 0.1 0.2 0.4 0.0 0.5 0.1 0.1 0.1 0.2 0.4 0.1 1.8 0.4 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.6 0.8 0.6 0.7 0.0 0.5 0.2 0.5 0.1 0.3 0.0 0.3 0.6 0.1 1.2 1.1 2.2 1.3 0.8 1.7 1.9 3.3 1.5 1.3 1.6 1.0 0.2 0.0 0.0 0.0 0.8 0.3 0.8 3.4 0.0 0.8 0.4 1.0 0.5 0.0 4.2 5.5 0.0 0.3 0.4 31.2 1.9 0.7 0.0 26.7 0.5 0.2 2.4 0.0 1.9 0.8 0.2 0.6 0.5 1.2 0.0 0.3 0.4 0.0 0.3 0.0 4.3 3.2 0.0 0.0 0.9 0.2 0.9 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.6 1290.4 0.4 0.4 0.7 6.1 1.0 50.1 0.2 0.0 1.2 0.8 0.7 1.6 0.0 0.6 0.3 1.4 0.4 9.1 0.5 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal keratinocytes: 167.1;Distal enterocytes: 125.6;Suprabasal keratinocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 31.6;HeLa: 19.6;hTERT-HME1: 17.8;RT4: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" NA NA 24400 21000 "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" 18.6 1.6 1.2 4.0 1.5 1.6 6.0 1.3 1.6 5.2 0.9 15.1 6.6 5.2 0.6 5.5 3.8 16.1 4.0 1.8 1.4 3.9 5.8 18.8 1.9 1.9 2.2 2.8 9.2 3.2 2.3 11.5 2.1 1.9 13.6 1.3 2.1 1.2 2.2 10.6 9.7 2.6 1.5 12.4 20.7 0.5 2.1 0.4 18.9 2.7 1.8 17.2 6.4 2.2 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.8 3.4 0.0 0.0 31.6 0.1 0.0 0.5 1.1 0.0 10.5 6.2 2.7 0.0 0.0 5.5 0.0 19.6 0.1 1.5 0.0 0.8 0.2 9.2 0.0 17.8 4.0 6.3 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.8 3.7 0.8 6.2 0.1 0.4 2.3 25.0 1.1 1.6 7.3 0.0 0.0 5.5 0.0 6.5 1.5 1.8 2.7 0.0 0.9 0.3 0.9 0.0 3.0 1.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 1.5 1.3 1.6 1.8 1.4 1.9 2.2 2.1 1.5 2.1 2.2 9.4 80.1 155.9 0.3 1.1 167.1 45.1 11.0 70.0 0.4 1.4 2.2 4.7 42.9 10.5 1.8 0.0 0.1 3.8 125.6 0.0 23.3 0.3 1.7 34.8 24.1 11.3 0.0 1.1 9.8 0.2 20.2 33.6 3.0 8.8 1.9 41.4 3.4 3.6 0.0 3.5 23.8 0.0 2.9 16.8 0.2 5.9 2.9 8.8 2.8 0.6 6.2 0.0 8.5 1.4 33.5 60.3 0.0 1.3 47.5 28.3 2.1 0.8 0.2 19.7 36.5 48.8 0.0 0.3 43.1 119.3 0.1 2.1 4.3 48.2 43.3 BRMS1 DKFZP564A063 ENSG00000174744 "BRMS1 transcriptional repressor and anoikis regulator" Q9HCU9 11 66337333-66345125 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010824, HPA019637" Approved Approved Centrosome NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "CAB010824: , HPA019637: AB_1845448" "unprognostic (1.75e-1)" "unprognostic (2.64e-2)" "unprognostic (2.01e-1)" "unprognostic (4.31e-2)" "unprognostic (1.72e-2)" "unprognostic (5.50e-2)" "prognostic unfavorable (6.74e-4)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (4.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (5.67e-3)" "unprognostic (2.54e-1)" "unprognostic (6.32e-2)" "unprognostic (1.61e-1)" 27.2 28.1 25.3 24.1 27.0 52.2 27.1 27.2 28.5 22.0 26.9 28.9 26.0 20.5 17.5 36.7 20.0 18.0 26.0 26.6 25.4 35.0 29.1 25.0 32.2 27.4 27.1 19.9 40.9 19.3 17.9 19.5 26.8 33.9 19.2 9.1 30.5 18.3 38.0 41.5 29.6 13.1 26.5 38.3 31.6 31.5 27.1 28.7 26.5 13.8 25.6 25.1 25.8 28.0 80.3 102.4 33.8 56.6 35.1 36.1 47.8 54.4 58.9 95.9 63.9 84.1 51.2 53.5 78.9 53.8 82.5 91.7 64.9 99.2 45.0 63.9 53.9 49.2 54.2 62.1 65.1 71.3 54.9 41.2 104.5 97.0 72.2 29.1 59.9 60.1 59.0 24.3 58.0 128.9 87.5 169.1 73.3 61.2 95.3 73.2 62.2 100.0 60.1 45.6 70.8 57.0 67.2 68.6 180.9 24.6 83.5 43.7 58.2 71.9 68.2 117.1 68.8 50.2 53.8 85.3 93.0 46.2 78.8 45.6 79.4 80.8 61.1 77.3 65.1 79.2 65.2 58.6 62.4 75.6 56.3 54.3 104.2 51.3 69.9 67.3 79.9 67.3 25.3 27.0 27.2 28.5 26.6 25.4 27.4 27.1 26.8 26.5 27.1 28.0 27.2 16.0 26.9 4.2 42.7 58.1 28.5 45.0 33.6 12.3 31.7 27.6 11.7 40.0 22.6 22.0 6.2 61.5 37.1 109.0 54.8 72.6 7.4 25.6 16.6 30.8 32.3 33.7 2.9 117.9 68.5 22.9 33.1 18.6 27.8 21.4 28.2 21.5 67.6 11.8 2.2 54.0 32.6 51.3 41.7 9.9 22.4 39.1 28.4 5.6 68.3 31.7 56.7 3.0 5.1 85.7 85.6 14.7 30.5 40.6 80.5 51.1 22.2 14.9 6.6 23.1 27.3 35.8 39.4 32.2 60.0 71.7 42.5 21.1 61.3 29.8 BRPF3 KIAA1286 ENSG00000096070 "Bromodomain and PHD finger containing 3" Q9ULD4 6 36196744-36232790 "Plasma proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022787 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Mitochondria "HPA022787: AB_1845454" "unprognostic (1.44e-1)" "unprognostic (2.24e-1)" "unprognostic (5.52e-2)" "unprognostic (2.15e-2)" "unprognostic (2.98e-1)" "unprognostic (9.51e-2)" "unprognostic (5.33e-2)" "unprognostic (3.78e-1)" "unprognostic (3.02e-2)" "unprognostic (1.07e-1)" "unprognostic (7.98e-2)" "unprognostic (3.74e-1)" "unprognostic (3.59e-2)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (1.28e-1)" "unprognostic (1.28e-1)" 6.6 11.9 3.5 7.6 4.3 12.1 8.4 9.0 5.4 8.4 0.1 13.1 11.7 11.9 6.1 7.9 8.8 8.6 7.3 5.5 1.9 11.8 6.9 7.4 6.2 0.6 1.4 11.9 18.0 14.5 4.4 7.5 0.7 9.6 12.9 6.4 15.7 10.9 12.1 12.6 13.8 10.2 0.3 9.0 10.7 19.9 2.1 9.4 12.1 12.2 6.2 7.4 4.7 4.0 10.6 10.0 24.6 19.4 13.3 11.2 21.0 15.6 16.3 21.5 16.9 29.4 9.8 16.3 16.4 15.4 27.0 10.0 21.8 11.2 18.8 15.6 13.5 11.5 9.3 17.6 14.0 9.1 15.5 14.4 9.4 25.6 12.8 15.6 16.3 7.7 24.5 14.6 11.9 15.0 10.4 3.9 12.4 12.9 8.5 29.9 10.1 5.1 6.9 21.4 35.0 11.0 12.7 13.8 12.9 15.1 15.4 24.6 17.2 22.3 18.9 6.1 18.3 12.0 16.8 12.1 3.7 14.1 26.9 0.7 0.0 0.3 0.4 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.4 0.0 0.0 0.1 0.2 0.1 3.5 4.3 9.0 5.4 5.5 1.9 0.6 1.4 0.7 0.3 2.1 4.0 5.7 6.4 12.7 8.8 5.6 9.6 7.2 4.6 9.6 9.0 21.1 11.7 13.7 10.0 7.3 5.5 6.2 4.8 9.7 28.1 0.0 6.6 15.3 7.3 10.9 7.2 19.7 5.7 16.6 10.8 4.1 9.8 10.2 12.7 2.5 16.6 9.7 18.2 4.5 0.0 11.4 27.5 6.1 5.7 6.6 14.0 11.1 4.9 7.2 6.5 5.4 6.1 9.2 13.6 11.0 11.2 13.6 9.4 10.5 11.3 21.5 13.5 4.5 7.2 0.0 11.1 8.0 25.7 17.5 7.3 11.4 8.2 6.3 14.2 16.2 10.2 BSG "CD147, EMMPRIN, EMPRIN, OK" ENSG00000172270 "Basigin (Ok blood group)" P35613 19 571277-583494 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1535.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1408.0;Syncytiotrophoblasts: 1654.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002427, HPA036048, HPA074870" Enhanced Approved Vesicles NA NA 340000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB002427: AB_563501, HPA036048: AB_2674917, HPA074870: AB_2686719" "unprognostic (1.88e-1)" "unprognostic (4.85e-2)" "unprognostic (9.53e-3)" "prognostic favorable (2.59e-4)" "unprognostic (3.34e-1)" "unprognostic (1.38e-2)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.54e-3)" "unprognostic (1.55e-1)" "unprognostic (9.46e-2)" "unprognostic (4.48e-3)" "unprognostic (2.61e-2)" "prognostic favorable (1.95e-6)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (7.30e-2)" "unprognostic (3.22e-1)" 378.6 518.8 652.6 154.5 615.4 431.3 313.8 575.6 847.5 320.6 975.8 543.5 231.3 413.3 259.5 245.1 323.1 176.2 1535.0 629.0 606.0 469.7 186.0 253.6 101.9 578.5 611.2 300.7 301.6 255.3 331.2 320.2 599.8 228.8 155.9 189.6 274.8 194.4 472.3 226.6 239.7 164.1 551.0 200.0 455.8 486.0 724.3 92.8 302.1 292.2 74.2 366.9 233.0 581.2 622.6 739.3 339.5 852.3 975.0 426.0 800.4 499.2 507.6 506.1 437.9 607.1 569.4 208.4 564.3 383.5 148.7 967.8 341.0 575.0 129.6 468.1 840.3 150.0 545.5 812.3 683.6 361.6 679.0 455.5 578.5 302.4 304.5 613.1 383.3 198.3 722.9 992.5 298.6 1015.8 261.6 706.6 901.9 353.7 408.3 522.8 301.2 745.2 655.9 412.1 561.0 539.1 984.4 408.1 769.7 257.9 432.3 1118.9 478.7 557.5 353.4 940.1 751.5 639.7 701.8 201.1 1066.9 510.2 712.8 189.0 324.7 348.9 226.4 245.9 200.5 115.0 150.7 218.4 209.6 93.2 114.0 144.7 474.8 173.5 284.2 235.2 192.0 434.0 652.6 615.4 575.6 847.5 629.0 606.0 578.5 611.2 599.8 551.0 724.3 581.2 313.5 22.4 31.5 75.1 101.5 208.6 176.8 668.0 91.0 157.7 202.8 187.6 80.6 128.7 253.4 286.9 204.3 1408.0 156.5 1140.1 146.8 580.9 261.6 156.6 296.6 246.7 255.1 1091.4 35.4 371.4 1095.5 279.8 192.1 190.1 116.2 181.1 132.1 96.9 416.7 139.7 31.4 337.2 510.6 137.8 179.6 600.2 300.4 139.8 506.9 122.7 264.5 495.5 221.4 20.6 30.7 458.0 929.1 336.7 192.4 172.8 450.7 306.7 178.8 269.2 203.8 74.3 235.6 347.9 604.4 127.7 156.7 1654.9 130.9 223.5 478.2 181.4 C10orf99 "AP-57, CSBF, FLJ21763, RLLV1833, UNQ1833" ENSG00000188373 "Chromosome 10 open reading frame 99" Q6UWK7 10 84173801-84185294 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 193.2;intestine: 274.9;vagina: 115.3" "Group enriched" "Detected in some" 11 "Distal enterocytes: 853.2;Intestinal goblet cells: 267.6;Paneth cells: 815.9;Proximal enterocytes: 364.8;Undifferentiated cells: 402.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 91.5;head and neck cancer: 102.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 52.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050920 Enhanced "Secreted in other tissues" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA050920: AB_2681274" "unprognostic (3.13e-2)" "unprognostic (1.43e-1)" "unprognostic (6.04e-2)" "unprognostic (1.78e-2)" "unprognostic (7.46e-3)" "unprognostic (2.05e-1)" "unprognostic (7.98e-2)" "unprognostic (2.04e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (3.70e-1)" "unprognostic (4.67e-2)" 0.4 0.0 0.0 16.8 0.0 0.0 0.5 0.0 0.0 46.7 0.0 268.5 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 274.9 0.1 21.7 2.6 0.0 38.5 21.5 13.1 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 17.4 33.5 115.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 6.8 1.2 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.1 853.2 0.0 0.0 0.4 3.3 0.8 0.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 267.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 815.9 0.0 0.0 1.0 364.8 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 46.0 2.3 0.0 1.4 0.0 402.8 46.4 C1orf210 "MGC52423, TEMP" ENSG00000253313 "Chromosome 1 open reading frame 210" Q8IVY1 1 43281877-43285617 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.9;Paneth cells: 100.8;Proximal enterocytes: 128.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 14 "basophil: 2.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.2" "Cell line enhanced" "Detected in some" "A-431: 12.1;BEWO: 13.0;CACO-2: 12.6;CAPAN-2: 39.8;OE19: 33.1;SK-BR-3: 13.8;T-47d: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013788 Uncertain Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "HPA013788: AB_1845637" "unprognostic (1.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.54e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (0.00e+0)" "unprognostic (7.57e-3)" "unprognostic (3.94e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-2)" 0.2 0.1 0.3 2.9 0.3 0.2 14.5 0.7 0.5 8.2 0.3 32.4 43.9 1.3 13.0 17.0 6.1 9.9 0.1 0.3 0.2 21.8 6.2 9.0 0.1 0.3 0.4 0.1 22.8 10.3 8.4 1.6 0.4 8.1 30.2 0.5 19.5 3.8 0.0 16.2 38.7 1.2 0.2 0.1 29.1 0.3 0.3 1.0 16.9 0.0 2.3 3.2 8.1 0.8 12.1 0.0 0.0 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 12.6 39.8 0.0 0.3 0.0 0.0 9.0 0.0 5.6 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.0 0.0 0.2 0.1 33.1 0.0 0.1 0.1 0.4 1.0 7.8 4.6 0.3 0.1 13.8 0.0 2.1 15.2 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.7 0.5 0.3 0.2 0.3 0.4 0.4 0.2 0.3 0.8 0.1 22.4 16.1 0.3 0.6 1.1 6.2 11.5 2.8 0.0 22.4 12.8 0.0 28.6 13.8 22.0 0.0 12.9 0.0 125.9 29.4 21.3 0.1 8.5 1.4 0.2 33.6 0.0 0.0 33.7 3.9 0.2 25.5 14.2 0.0 0.0 0.0 1.2 0.7 0.0 0.0 42.4 8.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.3 100.8 0.0 0.0 6.6 128.1 39.6 7.3 0.0 0.0 0.0 0.7 0.3 0.0 8.9 2.6 4.7 0.3 0.0 37.0 8.8 C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Distal enterocytes: 40.6;Proximal enterocytes: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 50.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA011044: AB_2668414, HPA075369: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favorable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" 6.6 8.2 26.9 6.5 27.6 13.6 5.8 15.5 28.9 6.4 15.3 11.1 16.1 6.2 4.8 10.8 8.8 5.3 10.2 26.8 19.6 11.6 13.1 10.3 8.1 18.0 18.4 6.0 11.0 5.7 23.9 3.9 18.4 7.1 7.3 14.1 9.6 5.3 15.3 15.3 17.1 5.1 15.2 14.9 8.1 4.3 21.4 8.5 6.7 7.3 5.7 7.0 6.6 23.7 6.1 4.5 6.0 12.5 7.7 3.2 3.9 9.0 7.8 8.7 7.2 7.3 6.3 9.1 23.1 6.3 9.1 13.4 7.6 3.9 3.4 14.3 6.2 35.7 5.9 5.3 10.2 10.5 50.5 3.7 7.9 16.4 6.1 9.8 5.4 13.5 15.1 16.1 8.3 16.2 11.9 24.9 2.2 15.0 11.8 7.4 5.3 10.5 8.7 3.8 18.7 10.5 3.8 20.1 5.9 2.3 35.3 13.9 6.7 8.1 2.8 9.9 16.1 6.8 4.5 3.5 4.9 17.6 9.1 0.5 1.3 2.7 0.2 1.4 0.4 0.1 0.6 0.6 0.5 0.0 0.6 0.3 0.4 0.8 2.0 0.3 0.6 0.5 26.9 27.6 15.5 28.9 26.8 19.6 18.0 18.4 18.4 15.2 21.4 23.7 5.1 6.4 4.2 9.4 3.7 10.7 1.6 2.3 10.2 15.6 6.8 5.0 2.4 2.8 4.3 1.8 37.5 0.9 7.4 40.6 3.9 3.4 5.4 12.1 2.6 5.7 1.2 7.0 15.1 2.8 1.7 2.5 3.6 4.6 2.5 2.2 11.4 5.4 9.4 21.9 15.0 8.0 0.0 13.9 16.1 1.3 2.1 11.4 7.2 5.6 15.3 5.9 7.2 4.5 8.4 5.1 10.4 1.5 7.2 3.2 33.0 4.0 21.9 29.9 6.6 2.1 3.6 3.7 2.0 10.3 10.9 1.1 8.6 3.6 5.5 1.9 C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Distal enterocytes: 61.3;Exocrine glandular cells: 51.8;Oligodendrocyte precursor cells: 46.8;Pancreatic endocrine cells: 53.6;Paneth cells: 67.2;Proximal enterocytes: 52.3;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.6" "Group enriched" "Detected in some" 5 "OE19: 64.6;RT4: 81.0;SK-BR-3: 32.6;T-47d: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Supported "Cell Junctions" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" 3.4 0.3 2.7 3.0 2.9 3.8 3.8 5.3 4.3 10.2 5.9 25.5 17.7 6.7 0.2 2.1 2.8 9.2 0.4 3.5 4.2 12.4 36.0 3.7 0.5 4.9 4.9 0.2 24.9 16.0 1.2 7.6 4.2 1.7 23.7 4.6 28.2 6.8 0.2 1.6 19.6 4.0 4.5 0.3 20.7 1.4 4.9 0.2 1.5 0.4 4.3 8.8 2.9 4.1 0.1 0.2 3.2 0.3 0.0 0.0 4.2 0.7 0.0 0.0 0.0 12.6 5.2 0.1 3.0 0.0 0.1 0.4 0.2 0.8 0.1 0.0 0.4 0.0 8.3 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 14.3 0.2 0.2 0.5 64.6 1.7 0.1 7.8 0.2 12.7 81.0 0.9 0.3 0.5 32.6 1.0 4.0 113.1 0.7 0.6 0.4 4.5 0.2 1.6 0.2 0.1 0.5 0.0 6.9 5.6 0.9 1.4 2.1 0.6 0.2 0.4 0.2 0.3 0.4 0.2 0.5 0.5 0.8 8.6 0.8 0.1 1.6 0.7 0.3 2.7 2.9 5.3 4.3 3.5 4.2 4.9 4.9 4.2 4.5 4.9 4.1 0.3 0.0 12.6 45.4 0.7 0.3 7.8 4.9 0.0 0.6 7.1 3.9 0.2 27.1 10.1 11.0 0.0 6.7 0.2 61.3 11.7 25.2 1.2 9.5 0.4 0.9 9.6 0.0 2.3 51.8 4.7 0.3 33.6 5.5 0.0 0.0 0.0 13.1 0.7 0.0 2.4 28.0 4.1 0.0 0.3 2.4 0.0 0.2 3.6 22.5 0.6 5.3 0.0 46.8 1.8 53.6 67.2 0.0 0.0 7.8 52.3 9.2 12.3 1.0 0.0 0.2 0.9 0.3 0.2 0.5 0.0 47.5 0.4 0.1 31.8 19.1 C4orf48 ENSG00000243449 "Chromosome 4 open reading frame 48" Q5BLP8 4 2041993-2043970 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.9;choroid plexus: 62.6;pituitary gland: 74.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 412.4;Paneth cells: 484.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 158.3;NB-4: 117.3;PC-3: 343.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052447 Uncertain Approved Cytosol "Secreted to blood" NA NA 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA052447: AB_2681837" "unprognostic (7.96e-2)" "unprognostic (2.57e-3)" "unprognostic (2.08e-1)" "unprognostic (3.20e-2)" "unprognostic (4.01e-2)" "unprognostic (8.26e-2)" "unprognostic (4.85e-3)" "unprognostic (2.51e-3)" "unprognostic (2.28e-3)" "unprognostic (1.80e-1)" "unprognostic (1.95e-2)" "unprognostic (5.55e-2)" "unprognostic (3.42e-2)" "unprognostic (5.38e-3)" "unprognostic (2.68e-1)" "unprognostic (5.55e-2)" "unprognostic (3.17e-3)" 13.5 18.3 50.0 4.6 68.4 2.7 9.6 71.0 66.6 5.2 62.6 20.4 2.7 5.5 0.2 4.3 7.8 0.4 8.2 49.4 60.8 20.2 4.0 7.9 1.3 81.5 63.2 6.6 18.9 2.4 74.5 2.1 58.6 7.1 0.9 0.2 9.2 1.4 1.2 3.1 16.3 0.6 67.8 18.5 11.9 56.1 60.3 0.3 9.3 0.0 0.6 6.8 2.9 97.9 33.4 27.1 5.3 24.9 2.4 3.9 35.3 31.2 6.0 5.6 5.3 18.6 19.6 4.4 29.2 1.2 10.4 9.2 0.6 3.5 1.7 20.1 158.3 10.5 15.8 10.7 5.2 21.7 70.3 3.0 5.9 1.2 0.0 1.8 5.9 17.9 35.1 0.1 3.9 20.6 24.6 117.3 15.8 1.8 343.1 56.1 8.3 11.2 5.0 12.3 42.7 60.0 15.3 0.7 47.7 0.5 8.3 10.3 26.5 14.7 31.9 11.0 35.3 23.8 22.4 0.4 14.6 13.2 20.8 88.5 451.6 431.5 123.6 325.6 127.5 187.7 157.2 138.3 270.0 167.9 89.1 92.9 349.2 29.6 290.7 301.1 199.8 192.8 50.0 68.4 71.0 66.6 49.4 60.8 81.5 63.2 58.6 67.8 60.3 97.9 13.3 0.0 1.9 8.8 58.1 21.9 6.6 13.2 7.4 12.0 147.0 139.8 10.6 20.0 14.2 200.5 0.0 8.0 52.8 412.4 70.5 320.8 97.1 326.7 92.6 42.1 235.1 30.7 5.6 222.7 116.5 47.7 35.7 107.3 107.5 209.0 123.1 11.9 235.5 18.5 8.2 154.2 44.7 272.1 113.3 350.5 19.3 158.9 327.3 7.5 205.2 78.8 20.6 6.0 41.1 198.2 484.2 28.2 84.1 10.9 223.7 7.9 28.8 15.0 13.1 1.7 53.2 99.7 193.2 5.7 10.1 13.1 73.9 50.9 117.1 11.1 C8orf33 FLJ20989 ENSG00000182307 "Chromosome 8 open reading frame 33" Q9H7E9 8 145052465-145066685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024812, HPA026104" Approved Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA024812: AB_10599490, HPA026104: AB_10600875" "prognostic unfavorable (2.77e-4)" "unprognostic (6.51e-3)" "unprognostic (1.85e-1)" "unprognostic (5.06e-2)" "unprognostic (1.12e-1)" "unprognostic (9.56e-3)" "prognostic unfavorable (8.95e-4)" "unprognostic (4.75e-2)" "unprognostic (3.51e-1)" "unprognostic (2.45e-2)" "unprognostic (5.17e-2)" "unprognostic (2.71e-1)" "unprognostic (1.05e-1)" "unprognostic (5.29e-2)" "unprognostic (1.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" 16.5 42.1 32.3 13.1 32.1 18.2 24.8 33.5 41.7 17.7 28.3 21.7 13.1 20.4 27.1 19.5 22.8 16.5 22.3 32.0 33.1 18.7 17.1 15.0 18.2 33.3 34.3 40.7 20.8 34.0 5.6 21.1 32.8 18.8 33.4 24.6 16.4 24.2 16.9 17.4 10.2 19.6 32.4 12.2 11.5 13.1 32.7 19.3 33.2 26.0 18.4 18.8 8.9 33.3 28.3 32.7 45.8 22.7 51.3 35.5 17.2 16.6 41.7 42.0 23.3 9.2 39.2 30.3 55.3 40.5 19.5 22.4 67.5 41.2 45.3 15.0 48.4 38.1 32.1 11.5 53.1 30.6 15.1 41.0 60.4 43.0 96.8 34.5 28.1 44.9 75.4 26.3 46.1 42.4 86.3 12.3 31.8 89.1 55.2 51.2 14.9 46.6 44.1 16.3 44.1 39.1 44.3 39.3 39.0 26.1 41.1 29.1 13.8 27.5 37.3 24.2 37.8 21.7 16.9 72.2 65.9 47.0 55.1 1.0 13.7 8.7 16.3 17.4 18.4 13.4 16.2 17.8 19.6 13.3 21.3 15.6 1.4 28.2 16.0 18.4 12.6 16.3 32.3 32.1 33.5 41.7 32.0 33.1 33.3 34.3 32.8 32.4 32.7 33.3 67.8 28.9 27.2 4.9 34.8 44.4 32.8 31.9 24.5 48.3 52.8 47.9 18.4 45.8 33.8 25.8 31.3 36.9 45.3 180.5 62.6 79.5 5.6 49.9 55.1 50.2 35.3 17.5 5.7 64.9 40.2 41.7 20.9 53.0 21.5 58.5 37.1 66.8 28.7 50.5 6.0 36.4 14.2 21.5 21.2 5.6 37.9 23.0 16.0 7.5 32.3 61.2 45.3 4.0 6.0 55.3 37.7 38.7 20.4 48.1 22.1 66.1 26.6 54.5 26.3 32.8 37.9 26.2 34.8 25.4 42.9 24.9 23.6 94.9 53.0 28.5 CA12 HsT18816 ENSG00000074410 "Carbonic anhydrase 12" O43570 15 63321378-63381846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 290.2;skin 1: 142.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 174.6;Distal enterocytes: 422.6;Paneth cells: 160.8;Squamous epithelial cells: 185.3;Suprabasal keratinocytes: 252.2;Undifferentiated cells: 138.8" "Cancer enhanced" "Detected in all" "renal cancer: 109.3" "Region enhanced" "Detected in many" "basal ganglia: 42.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 213.0;ASC TERT1: 213.0;RT4: 226.2;SK-BR-3: 177.9;T-47d: 286.8;U-138 MG: 300.5;U-87 MG: 361.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008773, CAB025181, CAB062549, CAB068179, HPA073203" Enhanced NA NA 52000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB025181: , CAB062549: AB_2665617, CAB068179: AB_2665616, HPA008773: AB_1078394, HPA073203: AB_2686580" "unprognostic (2.01e-1)" "unprognostic (8.38e-3)" "unprognostic (3.47e-1)" "unprognostic (3.25e-3)" "unprognostic (2.73e-2)" "unprognostic (2.47e-2)" "unprognostic (7.48e-2)" "unprognostic (3.43e-3)" "unprognostic (2.29e-1)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.80e-6)" "unprognostic (2.59e-1)" "unprognostic (1.51e-1)" "unprognostic (2.38e-1)" "unprognostic (6.56e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-1)" 8.3 0.2 6.1 18.7 42.9 0.1 42.8 5.2 7.2 50.7 129.0 104.1 0.4 28.4 4.1 75.4 25.0 7.7 3.2 6.8 6.6 290.2 0.7 3.0 0.3 0.9 9.6 0.6 70.2 0.3 10.7 2.3 3.2 5.5 94.2 1.9 26.3 8.7 0.6 142.1 8.2 56.2 0.9 0.8 7.9 0.6 16.1 0.1 4.6 0.1 8.7 27.4 49.0 1.5 0.0 213.0 3.5 0.5 27.3 213.0 11.2 15.7 13.7 2.5 4.1 1.6 0.5 0.0 51.4 12.6 81.7 1.1 0.0 10.4 6.2 0.3 7.7 0.0 13.9 0.4 0.6 0.0 0.3 81.3 11.4 63.6 20.4 0.1 2.7 0.1 0.0 0.3 2.8 125.2 0.3 0.2 3.4 0.0 33.4 0.1 0.0 0.1 0.2 226.2 1.8 0.2 0.9 177.9 0.0 2.1 286.8 0.1 0.4 300.5 16.0 10.1 0.2 0.0 0.0 0.1 361.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 42.9 5.2 7.2 6.8 6.6 0.9 9.6 3.2 0.9 16.1 1.5 0.7 0.0 6.9 11.4 1.1 174.6 20.0 87.7 93.4 0.1 93.5 50.4 1.3 1.5 30.3 40.5 0.0 0.4 1.6 422.6 54.8 17.2 12.1 28.4 6.2 2.1 8.4 0.0 1.3 58.4 2.0 14.6 8.2 75.0 1.3 0.3 0.0 0.2 0.6 0.0 0.8 111.4 20.3 0.3 11.9 3.9 0.0 4.0 23.2 0.0 0.0 2.7 0.0 1.0 0.1 10.2 160.8 0.0 0.0 19.8 15.6 73.9 6.9 0.2 0.0 0.2 4.1 0.0 0.0 185.3 252.2 1.8 2.8 0.1 138.8 17.4 CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149942-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.6" "Group enriched" "Detected in many" 16 "Adipocytes: 704.2;Distal enterocytes: 1289.3;Paneth cells: 2368.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 99.5" "Lineage enriched" "Detected in single" 995 "granulocytes: 99.5" "Cell line enhanced" "Detected in single" "OE19: 1.1" "Region enriched" "Detected in all" 5 "cerebellum: 300.3" "Low region specificity" "Detected in all" "HPA011089, HPA017258" Enhanced Uncertain Vesicles,Cytosol NA NA 190000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA011089: AB_1845996, HPA017258: AB_1845997" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.78e-3)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.84e-2)" "unprognostic (7.76e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.68e-3)" "unprognostic (8.59e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-2)" 83.0 2.3 17.8 3.1 18.8 19.5 80.9 86.8 34.2 12.7 13.9 263.6 3.8 6.0 51.9 1.0 5.0 38.3 55.2 22.8 13.9 47.6 0.7 87.2 0.6 13.4 17.8 6.2 31.8 16.9 15.7 8.6 22.8 8.2 172.6 0.1 10.4 36.9 30.5 3.8 11.2 2.7 12.7 16.0 10.0 1.3 15.1 1.6 74.6 42.3 0.1 6.2 5.6 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 99.5 0.0 0.0 0.0 0.0 0.1 17.8 18.8 86.8 34.2 22.8 13.9 13.4 17.8 22.8 12.7 15.1 14.9 704.2 0.0 2.4 1.3 1.5 1.5 0.3 0.0 2.2 0.0 2.3 2.5 9.1 0.0 0.6 14.7 0.0 0.0 1.2 1289.3 33.2 11.7 0.5 0.6 13.0 88.3 19.3 0.0 3.8 0.2 0.0 4.4 0.0 0.2 11.4 23.2 1.4 0.0 0.6 0.0 1.4 24.6 0.0 0.0 1.2 0.1 0.6 1.1 0.0 23.4 0.0 0.1 0.0 1.0 0.4 0.1 2368.3 0.0 1.2 0.1 14.9 72.4 0.7 0.0 6.6 5.0 23.4 0.1 0.0 0.1 1.1 0.0 2.4 0.4 41.7 0.3 CA7 ENSG00000168748 "Carbonic anhydrase 7" P43166 16 66844414-66854153 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 57.0" "Cell type enriched" "Detected in some" 40 "Paneth cells: 3026.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 1.1;THP-1: 1.9" "Region enhanced" "Detected in all" "cerebellum: 67.2" "Low region specificity" "Detected in many" HPA047237 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047237: AB_2679994" "unprognostic (8.77e-4)" "unprognostic (5.23e-4)" "unprognostic (1.57e-1)" "unprognostic (1.96e-2)" "unprognostic (2.19e-1)" "unprognostic (2.16e-2)" "unprognostic (7.90e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "unprognostic (9.62e-2)" "unprognostic (1.69e-2)" "unprognostic (7.12e-3)" "unprognostic (8.47e-2)" "unprognostic (5.20e-1)" "unprognostic (1.90e-2)" "unprognostic (6.46e-2)" 0.0 0.0 5.1 0.2 6.7 0.0 0.1 4.8 10.7 0.0 2.1 57.0 6.9 0.1 0.9 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 0.0 0.0 3.8 3.5 0.0 0.0 0.0 0.1 0.0 3.5 0.0 48.6 0.0 0.0 0.2 0.0 0.0 10.0 1.1 2.6 0.0 0.0 0.5 4.7 0.1 0.0 0.2 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.7 4.8 10.7 8.0 3.1 3.8 3.5 3.5 2.6 4.7 5.6 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 74.2 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 16.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3026.3 0.0 0.0 0.5 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 39.9 0.1 CAB39 "CGI-66, MO25" ENSG00000135932 "Calcium binding protein 39" Q9Y376 2 230712842-230821075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 188.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037112, HPA076632" Approved Approved Nucleoli,Cytosol NA NA 100000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli Cytosol "CAB037112: AB_1078367, HPA076632: " "unprognostic (4.36e-3)" "unprognostic (1.42e-1)" "unprognostic (2.17e-2)" "unprognostic (1.71e-1)" "unprognostic (3.19e-1)" "unprognostic (4.73e-2)" "unprognostic (2.50e-2)" "unprognostic (2.84e-2)" "unprognostic (9.16e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (1.04e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.59e-1)" "unprognostic (2.92e-1)" "unprognostic (8.93e-2)" "unprognostic (1.36e-1)" 43.7 31.0 30.1 55.2 32.9 50.9 29.6 31.5 40.6 26.5 29.3 53.7 48.0 30.7 35.0 55.8 30.0 41.3 55.6 34.3 33.9 54.1 38.6 40.0 58.0 36.5 34.5 29.2 33.1 42.5 17.1 35.5 36.4 39.9 56.0 45.6 34.4 31.2 188.5 34.3 51.2 40.4 34.0 38.0 46.2 41.3 33.6 45.1 37.3 127.8 59.1 49.4 30.5 39.5 131.6 30.0 39.8 34.0 48.2 59.8 45.3 73.7 91.8 45.4 47.2 36.6 140.0 33.8 56.5 64.5 76.5 59.1 44.8 138.5 91.9 142.1 35.1 90.5 36.9 39.5 40.9 126.6 100.8 42.5 79.1 58.5 128.4 51.8 57.1 46.1 153.9 30.3 43.8 45.6 59.1 77.9 39.8 53.4 52.0 67.8 59.3 33.5 84.6 104.9 43.2 26.4 55.2 68.2 59.9 44.7 16.9 72.4 73.1 63.9 24.3 68.2 61.0 39.0 31.8 53.8 45.4 72.4 53.4 4.0 3.6 6.0 4.7 4.4 4.8 3.0 5.8 6.1 3.0 2.4 4.7 6.5 10.3 9.3 4.3 2.2 6.2 2.4 30.1 32.9 31.5 40.6 34.3 33.9 36.5 34.5 36.4 34.0 33.6 39.5 41.6 64.1 37.5 42.1 29.6 97.8 44.2 23.0 23.3 14.4 28.3 18.9 69.1 17.2 30.5 51.5 33.3 20.8 32.3 162.5 29.4 26.0 12.0 41.4 25.2 29.6 20.4 32.0 85.1 32.7 18.7 24.1 28.5 39.5 20.3 16.6 28.2 29.3 56.8 28.6 69.3 48.5 24.4 81.2 72.4 13.5 17.4 66.2 30.2 93.7 49.6 39.6 29.9 58.8 64.3 72.3 62.4 32.0 37.0 84.4 54.6 39.8 55.6 40.5 13.1 27.5 27.3 30.8 29.5 31.2 85.1 23.1 52.0 18.9 34.8 88.6 CACFD1 "C9orf7, D9S2135, flower" ENSG00000160325 "Calcium channel flower domain containing 1" Q9UGQ2 9 133459965-133470848 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.5;Gastric mucus-secreting cells: 67.2;Hepatocytes: 47.9;Paneth cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.8" "Group enriched" "Detected in many" 4 "B-cells: 2.0;granulocytes: 3.8" "Cell line enhanced" "Detected in many" "T-47d: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015280 Approved Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA015280: AB_1845833" "unprognostic (3.15e-2)" "unprognostic (4.25e-1)" "unprognostic (1.96e-3)" "unprognostic (4.48e-1)" "unprognostic (2.77e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-2)" "unprognostic (5.49e-2)" "unprognostic (3.97e-1)" "unprognostic (3.17e-1)" "unprognostic (1.67e-3)" "unprognostic (3.91e-2)" "prognostic favorable (2.83e-8)" "unprognostic (5.10e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (3.99e-3)" 5.1 11.3 6.4 1.9 6.2 2.4 7.0 8.2 6.9 9.5 6.9 19.9 5.8 9.9 5.3 9.9 9.3 4.5 11.2 5.8 6.0 28.2 58.6 12.8 1.5 7.5 6.1 10.7 18.9 7.9 19.0 1.2 6.0 13.3 2.8 2.1 15.8 4.0 9.0 5.4 14.9 2.4 5.9 7.3 28.4 23.9 6.5 0.9 17.4 1.8 1.7 11.8 6.9 7.8 0.4 2.1 4.3 2.7 0.8 0.1 2.5 2.0 2.9 1.5 0.3 5.7 4.8 0.2 4.2 2.0 2.6 1.2 2.2 1.6 0.0 1.1 1.4 0.6 4.8 2.5 2.5 0.0 0.6 0.0 3.2 1.3 1.0 4.8 1.8 1.1 0.8 1.8 2.4 3.7 0.3 0.7 3.4 3.3 1.5 1.4 0.6 9.3 2.9 1.7 4.9 9.1 2.5 5.6 0.9 2.6 9.5 1.6 0.4 3.5 2.2 0.6 0.1 3.4 4.8 2.4 1.1 0.3 1.1 3.8 0.5 1.6 0.2 0.0 0.0 2.0 0.1 0.4 0.4 0.7 0.1 0.5 0.0 0.6 0.2 0.2 0.2 0.1 6.4 6.2 8.2 6.9 5.8 6.0 7.5 6.1 6.0 5.9 6.5 7.8 1.7 19.2 19.6 3.3 5.5 2.8 5.5 5.0 3.4 4.6 13.0 8.9 9.8 21.5 8.8 20.2 12.5 1.9 1.0 75.5 3.9 22.0 13.4 9.8 5.4 3.8 29.2 0.0 5.8 33.1 3.3 4.0 67.2 15.1 4.5 5.9 5.3 47.9 3.6 3.3 4.8 43.1 10.2 5.6 2.2 8.1 8.1 2.1 5.4 1.9 5.9 6.7 2.1 4.5 4.7 26.2 53.2 7.5 3.9 7.0 31.7 16.5 5.2 9.8 0.0 3.4 4.4 13.7 14.7 2.9 1.6 2.9 1.9 2.9 24.5 6.2 CAMK2N1 CaMKIINalpha ENSG00000162545 "Calcium/calmodulin dependent protein kinase II inhibitor 1" Q7Z7J9 1 20482391-20486210 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 461.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 640.5;Intestinal goblet cells: 431.4;Paneth cells: 367.7;Proximal tubular cells: 519.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;MAIT T-cell: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Cell line enhanced" "Detected in many" "AN3-CA: 212.1;CAPAN-2: 199.1;Hep G2: 165.6;SK-BR-3: 159.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075200 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA075200: " "unprognostic (1.67e-1)" "unprognostic (2.70e-3)" "unprognostic (9.71e-3)" "unprognostic (3.13e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (1.37e-7)" "prognostic unfavorable (5.49e-4)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.77e-2)" "unprognostic (1.31e-1)" "unprognostic (7.48e-3)" "unprognostic (1.93e-2)" "unprognostic (1.40e-3)" "unprognostic (4.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-2)" "unprognostic (1.31e-2)" 20.1 61.6 340.5 9.3 322.3 0.5 19.8 172.0 461.3 32.5 115.4 85.0 80.4 27.8 38.1 27.8 22.3 27.4 22.3 354.6 206.5 86.2 53.8 67.9 1.9 224.8 222.4 30.2 8.8 42.4 37.7 11.6 215.9 35.8 77.0 32.6 30.4 40.8 7.1 12.0 86.9 22.7 226.7 12.2 19.5 4.7 265.4 2.0 10.8 9.9 7.0 27.3 24.3 348.6 63.1 17.5 15.0 212.1 28.4 52.6 2.2 52.6 119.0 9.5 4.8 20.1 199.1 6.3 14.7 21.7 7.7 103.2 4.6 90.0 5.9 11.7 3.8 1.3 0.9 165.6 31.4 0.1 6.2 8.4 41.2 5.6 21.2 19.6 16.4 4.3 6.3 0.5 105.8 17.4 0.2 0.5 2.8 109.7 3.9 5.6 9.4 0.4 59.3 93.5 57.6 16.2 28.5 159.6 16.3 10.2 30.6 0.6 5.0 34.9 46.1 48.5 21.1 0.1 0.1 2.5 119.5 13.5 22.0 0.0 0.0 0.0 1.6 0.0 1.1 0.5 0.5 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 340.5 322.3 172.0 461.3 354.6 206.5 224.8 222.4 215.9 226.7 265.4 348.6 28.3 3.2 1.1 35.6 7.6 9.3 11.7 2.3 0.6 248.6 96.5 104.5 20.8 178.7 2.5 248.3 6.2 0.5 10.1 640.5 229.0 20.1 0.8 6.2 45.6 20.0 299.2 8.0 132.5 40.8 2.9 65.1 9.2 12.0 1.3 4.6 9.3 201.6 0.3 85.8 108.7 431.4 14.2 1.9 12.1 3.9 62.7 5.6 39.2 26.2 0.6 81.1 0.0 27.6 249.1 141.5 367.7 94.0 3.5 37.7 183.2 519.2 1.2 35.6 131.5 86.2 96.4 0.8 2.8 1.0 7.5 2.1 14.7 0.8 223.5 50.3 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 276.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 516.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 44.8 43.1 27.8 51.9 26.1 66.5 48.4 29.7 30.1 80.9 28.3 78.6 80.4 56.3 27.5 276.2 92.3 55.5 53.1 27.7 33.0 53.1 44.3 56.9 57.0 41.4 31.5 44.5 71.7 36.6 40.8 56.2 43.4 62.1 57.6 9.6 118.7 67.4 84.8 125.1 88.1 45.3 33.9 50.2 65.5 6.1 37.9 49.5 71.5 55.3 86.4 83.4 117.4 27.4 285.6 147.9 42.9 97.2 77.9 104.3 127.0 84.1 144.2 103.0 74.9 94.8 250.2 71.2 136.0 179.3 111.1 409.8 60.9 366.9 32.2 76.4 44.1 170.8 80.4 93.7 76.2 40.6 228.0 107.3 196.8 85.9 43.2 92.6 178.5 50.6 103.1 55.9 87.4 181.8 83.1 130.6 120.5 145.2 133.8 80.7 43.0 43.2 138.1 516.5 76.2 55.7 87.4 331.4 80.3 45.8 142.8 77.9 147.1 73.1 50.5 159.0 38.5 33.8 26.9 86.6 127.5 48.8 82.3 87.6 57.5 77.9 39.4 51.2 31.0 30.8 30.7 35.8 48.4 31.7 17.6 24.9 33.1 34.8 30.4 38.1 35.9 74.8 27.8 26.1 29.7 30.1 27.7 33.0 41.4 31.5 43.4 33.9 37.9 27.4 27.3 25.6 27.9 21.5 39.6 59.9 127.3 120.5 56.9 10.7 44.7 36.6 22.0 74.4 81.0 77.3 20.9 238.5 61.4 184.2 39.2 180.5 0.5 41.9 26.3 31.3 44.3 58.3 15.9 115.8 111.7 39.6 57.6 58.2 46.9 48.6 37.9 36.7 88.7 21.9 15.2 76.9 59.0 51.2 34.0 2.0 43.5 67.1 48.0 14.0 112.7 38.5 61.8 6.6 1.9 179.4 124.1 50.8 17.7 78.6 155.6 34.6 71.1 16.2 39.5 25.3 36.7 0.5 2.8 102.0 68.9 196.6 40.2 35.4 125.3 156.6 CAPN15 SOLH ENSG00000103326 "Calpain 15" O75808 16 527712-554636 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 4.7;neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011960 Uncertain Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011960: AB_10610556" "unprognostic (4.11e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (2.66e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-2)" "unprognostic (1.54e-3)" "unprognostic (8.31e-3)" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.86e-1)" "unprognostic (4.02e-2)" "unprognostic (2.53e-3)" "unprognostic (2.54e-3)" "unprognostic (5.91e-2)" "unprognostic (1.83e-1)" "unprognostic (9.23e-3)" 13.0 12.0 3.6 7.2 2.5 8.1 10.8 11.6 6.2 12.2 0.2 20.2 16.3 13.4 0.4 18.5 13.2 1.6 11.2 3.2 0.2 18.4 17.2 15.3 5.1 4.1 1.0 13.2 24.8 2.2 15.2 2.6 1.4 12.3 2.3 1.1 12.6 2.8 14.9 22.3 22.7 1.2 0.2 21.2 16.5 18.7 2.1 2.8 11.7 0.9 2.5 12.5 12.8 0.8 16.8 21.5 3.0 9.3 1.7 3.4 46.2 17.5 4.6 4.9 3.3 28.2 12.1 24.0 16.3 3.2 5.0 21.9 2.0 6.9 1.8 25.2 37.1 20.2 25.7 17.6 7.3 23.8 27.3 3.9 4.0 4.9 2.2 2.9 5.3 14.7 37.6 7.1 1.6 25.9 27.1 26.0 26.7 8.6 20.2 46.5 8.7 24.2 3.3 11.0 19.6 17.8 11.7 16.2 10.2 1.8 13.3 24.7 26.2 15.3 21.4 15.7 22.0 18.2 11.0 21.3 6.7 13.8 9.7 4.7 1.3 0.8 0.3 0.8 0.1 0.4 0.1 0.4 0.3 2.3 0.1 0.2 16.2 1.1 1.3 0.5 0.2 0.3 3.6 2.5 11.6 6.2 3.2 0.2 4.1 1.0 1.4 0.2 2.1 0.8 7.6 3.2 8.4 10.1 5.9 8.9 5.7 6.2 3.4 12.1 7.6 6.6 3.1 8.6 5.6 7.3 16.7 3.7 22.3 54.3 1.9 6.2 16.5 6.1 8.9 8.7 4.2 1.7 10.6 15.7 4.4 6.9 20.4 13.3 7.0 10.8 8.9 16.5 6.8 20.2 11.3 26.9 8.2 12.0 6.8 6.2 7.5 8.2 1.8 7.5 6.5 9.1 23.7 10.6 7.8 14.3 37.1 4.5 5.8 13.4 33.1 5.7 4.6 11.2 0.0 10.2 5.2 5.3 7.4 5.8 8.0 2.5 9.2 9.6 25.9 11.6 CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 60.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 170.3;Gastric mucus-secreting cells: 80.0;Intestinal goblet cells: 89.8;Paneth cells: 72.6;Proximal enterocytes: 75.6;Undifferentiated cells: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Cell line enhanced" "Detected in many" "OE19: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: AB_2686512" "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" 6.7 12.2 8.5 10.9 7.9 2.7 4.9 6.4 8.6 13.5 3.5 60.5 60.7 10.0 5.7 31.6 10.8 36.3 7.2 8.5 8.7 15.1 52.1 4.8 1.9 11.7 8.2 13.2 5.6 1.0 5.1 2.8 12.5 16.0 49.9 3.8 7.7 8.9 1.6 3.1 52.4 11.3 9.9 3.5 47.9 21.5 7.9 2.8 4.7 1.7 2.7 15.4 10.5 8.1 0.8 12.5 8.6 7.8 32.0 30.4 0.7 11.8 22.9 13.4 10.0 6.9 3.6 0.4 7.7 24.5 14.4 0.5 3.8 1.0 6.4 0.5 0.8 2.1 0.5 0.9 7.9 0.2 0.4 16.1 1.4 22.6 5.2 18.8 14.4 5.1 0.2 0.0 26.9 19.9 1.8 0.3 6.6 106.6 9.3 2.0 27.0 0.4 4.6 16.4 0.5 13.5 1.0 2.7 5.9 5.7 1.7 0.1 23.9 25.4 12.3 34.8 1.3 0.8 1.7 0.1 13.1 0.3 5.7 0.0 0.2 0.0 1.3 0.3 0.1 0.0 0.1 0.5 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.1 0.0 0.7 8.5 7.9 6.4 8.6 8.5 8.7 11.7 8.2 12.5 9.9 7.9 8.1 1.6 0.0 0.5 4.2 1.0 1.7 0.3 2.2 0.0 3.1 0.5 1.8 1.7 24.3 10.3 23.9 0.0 0.1 3.4 170.3 1.9 10.3 1.1 1.9 5.9 2.4 22.3 5.7 4.6 32.7 0.4 7.6 80.0 3.5 0.0 10.2 2.9 40.4 0.9 1.7 6.7 89.8 10.2 1.6 1.8 1.3 12.5 1.2 7.2 1.0 0.3 5.8 5.2 11.6 0.7 22.4 72.6 4.5 0.9 2.0 75.6 9.9 11.1 2.1 0.0 8.3 4.1 0.5 2.3 2.5 0.9 0.0 1.5 5.3 69.2 2.4 CAPNS1 "30K, CANP, CANPS, CAPN4, CDPS" ENSG00000126247 "Calpain small subunit 1" P04632 19 36139953-36150353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006872 Approved Approved Nucleoplasm,Cytosol NA NA 9000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006872: AB_1078382" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.03e-1)" "unprognostic (2.82e-3)" "unprognostic (1.25e-3)" "unprognostic (2.04e-2)" "unprognostic (6.40e-2)" "unprognostic (1.17e-1)" "unprognostic (5.53e-2)" "unprognostic (7.10e-3)" "unprognostic (1.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.51e-1)" "unprognostic (4.72e-2)" 425.4 357.9 363.0 171.4 374.4 235.7 371.7 359.4 507.1 368.1 353.9 371.4 263.2 303.5 193.8 761.7 306.6 197.8 692.5 379.8 411.1 488.5 273.5 396.7 167.4 401.0 392.3 267.6 250.9 330.9 317.9 147.3 401.0 357.0 287.6 136.2 374.9 281.4 491.3 211.9 341.4 290.0 356.5 363.6 311.1 273.6 400.3 200.8 329.9 373.4 275.1 354.8 402.5 384.1 395.2 977.6 240.0 342.7 566.3 683.0 48.2 315.8 673.4 631.3 488.1 223.3 572.2 141.9 463.7 1067.5 225.6 207.0 291.3 780.8 514.7 592.4 142.9 166.0 259.7 373.0 655.0 166.7 393.9 740.8 477.9 411.1 577.5 767.3 699.8 173.5 204.4 554.4 978.6 522.7 295.4 301.4 137.9 754.6 490.6 156.5 194.7 262.3 1208.8 368.7 159.1 199.4 385.1 532.0 155.5 279.4 308.6 261.4 460.6 555.5 424.3 188.1 318.7 198.4 277.6 126.8 630.4 225.9 480.8 24.8 50.1 22.6 44.4 75.6 28.5 29.4 30.9 36.4 46.1 32.3 18.7 25.2 25.2 24.6 83.4 58.7 34.7 21.1 363.0 374.4 359.4 507.1 379.8 411.1 401.0 392.3 401.0 356.5 400.3 384.1 172.7 125.0 98.6 10.4 49.3 30.7 76.2 69.1 29.6 21.1 91.7 75.1 149.5 130.1 85.9 163.7 0.0 74.9 107.1 250.1 62.6 226.3 102.9 168.5 118.3 136.6 107.8 47.3 13.4 251.3 87.8 83.3 66.8 234.4 63.4 84.7 157.1 78.4 155.1 16.8 11.9 220.3 52.9 244.6 86.9 230.2 93.2 130.5 39.2 15.9 208.4 78.2 109.2 6.6 21.9 254.2 187.5 76.0 50.2 98.0 243.5 135.3 74.6 33.1 46.0 64.3 92.9 120.1 6.5 109.1 28.8 70.1 62.8 132.2 165.6 112.4 CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.5;Ductal cells: 25.4;Endothelial cells: 24.8;Pancreatic endocrine cells: 39.4;Paneth cells: 27.6;Proximal enterocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 56.5;U-2197: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" 10.0 8.4 3.7 5.0 3.3 0.1 10.5 2.9 4.0 6.5 2.8 13.3 34.1 6.0 1.3 8.4 7.5 7.8 10.7 3.1 3.0 14.9 12.4 6.1 2.1 4.7 3.3 3.1 9.2 2.7 2.1 4.7 5.0 5.4 8.8 0.3 19.0 4.2 8.0 9.7 35.9 4.2 3.3 4.1 9.9 15.0 4.2 0.8 6.8 8.2 1.0 6.1 5.8 2.9 31.3 23.1 4.1 3.0 0.1 8.7 19.6 2.8 6.5 12.8 10.0 14.2 21.8 0.0 10.8 5.4 12.4 43.0 4.9 56.5 3.9 0.1 11.8 0.7 15.6 22.1 5.4 0.5 1.9 2.9 11.5 24.5 31.2 10.2 26.1 0.0 3.3 0.0 9.9 11.0 0.1 2.0 7.2 17.0 13.2 0.0 38.9 3.0 19.1 5.4 1.5 2.4 21.0 9.5 2.1 5.0 10.1 1.7 35.0 9.5 26.9 82.8 16.4 0.1 0.0 0.0 30.2 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.3 2.9 4.0 3.1 3.0 4.7 3.3 5.0 3.3 4.2 2.9 22.6 0.0 2.0 0.0 0.2 8.5 6.8 3.4 2.2 1.2 3.9 4.3 3.7 10.0 1.6 3.7 0.0 0.4 0.2 35.5 1.9 25.4 7.8 3.3 0.4 24.8 7.7 0.0 0.1 19.6 1.6 1.9 15.8 6.2 0.0 0.4 17.9 4.8 0.1 0.0 0.6 19.8 4.1 0.0 1.2 8.6 0.0 0.4 5.4 3.7 0.0 0.0 0.0 0.0 0.1 39.4 27.6 0.7 0.2 8.6 35.5 12.4 1.2 0.2 0.0 6.2 1.1 0.4 3.4 2.5 3.8 0.0 0.6 1.0 11.3 9.7 CASP10 "FLICE-2, MCH4" ENSG00000003400 "Caspase 10" Q92851 2 201182898-201229406 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 71.3;NK-cells: 44.3;Paneth cells: 44.5;Plasma cells: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 25.3" "Low region specificity" "Detected in all" "CAB003780, HPA017059" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "CAB003780: AB_289592, HPA017059: AB_1846040" "unprognostic (4.01e-2)" "unprognostic (8.24e-2)" "unprognostic (4.80e-1)" "unprognostic (1.28e-3)" "unprognostic (4.74e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.05e-7)" "unprognostic (3.23e-2)" "unprognostic (2.19e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" 8.8 2.4 5.7 9.2 5.5 19.5 6.5 4.5 5.8 4.0 4.4 13.2 21.8 3.3 6.2 8.8 5.4 7.4 6.7 4.7 5.1 8.1 6.2 11.5 8.9 6.0 5.0 1.6 4.8 2.3 1.3 9.6 5.8 3.9 13.4 1.3 5.4 3.1 4.9 5.7 18.4 5.1 5.6 22.6 10.2 1.2 7.3 8.7 5.3 2.8 10.4 9.0 5.1 5.4 4.4 3.5 0.3 0.4 0.1 0.3 7.5 0.7 4.6 0.4 1.8 4.6 9.8 0.5 7.0 2.5 1.7 2.9 0.2 2.3 1.3 2.1 4.8 12.2 4.0 15.1 1.6 8.3 12.7 0.5 2.0 5.3 0.4 0.3 25.3 5.1 14.9 17.4 0.4 0.3 15.9 7.8 0.6 6.0 2.4 8.8 0.5 18.4 8.7 6.2 0.2 0.1 4.1 0.2 1.9 3.0 0.2 7.8 10.0 0.4 0.8 3.4 0.2 18.7 12.1 0.5 4.5 6.3 0.2 5.9 11.7 0.7 6.4 16.5 5.6 8.2 5.2 3.6 6.5 7.7 7.2 6.4 2.1 8.5 19.3 6.6 1.2 7.2 5.7 5.5 4.5 5.8 4.7 5.1 6.0 5.0 5.8 5.6 7.3 5.4 20.7 19.2 10.0 0.3 15.8 6.0 2.7 10.6 5.2 0.0 1.3 0.9 1.8 8.6 9.4 9.2 0.0 1.1 20.5 71.3 1.9 16.2 1.2 7.7 7.4 29.7 2.4 14.9 0.3 10.4 0.7 4.2 26.5 12.0 7.6 0.8 26.4 7.1 9.4 0.0 0.5 21.6 4.1 26.6 17.5 0.0 0.6 16.2 7.2 33.7 22.0 0.5 44.3 0.0 0.9 8.6 44.5 0.0 49.7 2.5 26.1 8.7 24.4 0.4 0.0 2.9 2.2 0.1 0.1 6.6 4.5 0.4 12.9 4.1 16.4 10.3 CASP5 ICE(rel)III ENSG00000137757 "Caspase 5" P51878 11 104994235-105023168 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.0;intestine: 16.8;lymphoid tissue: 14.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 31.4;Paneth cells: 18.7;Proximal enterocytes: 17.2;Undifferentiated cells: 7.3" "Group enriched" "Detected in some" 7 "colorectal cancer: 3.9;stomach cancer: 1.3" "Region enhanced" "Detected in some" "cerebral cortex: 5.0" "Group enriched" "Detected in some" 13 "intermediate monocyte: 18.1;neutrophil: 13.0;non-classical monocyte: 41.2" "Group enriched" "Detected in many" 15 "granulocytes: 13.0;monocytes: 41.2" "Cell line enriched" "Detected in single" 6 "HHSteC: 3.7" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (4.30e-2)" "unprognostic (8.86e-2)" "unprognostic (1.07e-1)" "unprognostic (4.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.22e-2)" "unprognostic (9.90e-2)" "unprognostic (8.29e-3)" "unprognostic (1.47e-1)" "unprognostic (4.38e-3)" "unprognostic (7.39e-3)" "unprognostic (3.25e-1)" "unprognostic (1.82e-9)" "unprognostic (7.30e-2)" "unprognostic (2.67e-3)" "unprognostic (1.87e-1)" "unprognostic (1.50e-1)" 0.7 0.1 0.5 14.6 0.6 0.2 0.1 0.5 5.0 0.2 0.6 15.6 10.0 0.1 0.2 0.1 0.2 0.4 0.1 0.5 0.5 0.2 0.2 1.6 0.9 0.7 0.8 0.1 0.0 0.0 0.1 0.9 1.5 0.1 12.9 0.0 0.1 0.1 0.0 0.0 16.8 1.8 0.6 2.7 0.1 0.3 0.8 0.1 0.1 0.4 0.3 2.2 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.1 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 18.1 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.1 13.0 0.0 41.2 0.5 0.0 1.4 0.5 0.6 0.5 5.0 0.5 0.5 0.7 0.8 1.5 0.6 0.8 0.9 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.4 0.0 2.3 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.3 0.0 4.7 0.4 0.7 0.0 4.8 0.0 1.9 2.4 0.0 0.0 0.0 0.1 0.1 18.7 0.0 0.0 0.0 17.2 0.0 0.8 0.0 0.0 0.2 0.1 0.5 0.7 0.0 0.0 0.0 0.3 0.0 7.3 0.1 CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.1;Paneth cells: 113.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB025563 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB025563: " "prognostic favorable (2.11e-4)" "unprognostic (3.18e-2)" "unprognostic (2.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-3)" "unprognostic (3.96e-1)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "prognostic unfavorable (5.90e-4)" "unprognostic (5.45e-3)" "unprognostic (2.62e-1)" "unprognostic (2.86e-1)" "unprognostic (4.33e-3)" 21.0 10.3 11.8 26.2 12.2 8.4 18.6 11.5 20.4 18.4 12.8 75.1 65.3 16.3 10.5 15.4 17.9 16.8 11.3 11.8 12.0 19.6 23.6 24.9 16.9 12.3 12.5 16.2 22.4 10.4 7.0 20.9 11.9 21.3 58.2 6.8 34.1 12.3 13.8 17.4 68.1 18.5 11.4 17.5 45.5 6.8 12.8 19.8 10.2 14.5 18.4 31.6 16.1 12.8 28.9 29.4 24.1 13.0 43.4 37.5 16.7 32.9 49.9 56.1 69.7 22.4 51.0 30.1 19.0 29.8 21.1 24.8 30.4 24.2 39.5 46.9 41.0 19.6 22.0 38.0 28.9 20.9 24.7 24.5 15.9 32.0 13.3 25.0 75.4 28.2 5.3 39.8 21.1 38.2 51.1 16.0 4.4 31.7 17.3 51.7 98.0 18.1 44.8 21.4 1.9 14.4 24.9 35.5 17.6 23.1 43.1 18.4 37.8 12.8 24.1 13.5 27.7 30.7 20.1 0.8 13.1 38.7 14.3 22.9 14.7 11.7 11.1 21.3 9.5 11.5 9.2 14.1 10.4 9.2 7.1 9.7 2.6 7.4 18.5 1.4 14.0 9.8 11.8 12.2 11.5 20.4 11.8 12.0 12.3 12.5 11.9 11.4 12.8 12.8 36.3 9.6 12.3 27.4 13.8 19.8 21.2 26.0 13.1 0.6 15.8 9.9 2.5 11.5 26.2 22.0 0.0 12.4 10.3 229.1 11.7 46.1 0.3 21.0 22.9 23.8 9.6 4.0 1.6 39.0 25.5 16.2 30.1 13.5 12.7 10.9 17.2 15.6 17.0 0.0 1.1 81.1 28.5 12.8 6.9 0.6 9.6 18.4 7.2 10.3 68.9 7.9 13.4 1.0 0.8 37.2 113.4 4.1 21.5 42.6 88.0 25.9 42.8 1.7 19.7 12.3 16.3 2.9 28.2 13.3 14.8 10.9 15.7 5.2 50.7 39.0 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.3;intestine: 50.9;skin 1: 42.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.6;Pancreatic endocrine cells: 95.0;Paneth cells: 108.1;Proximal enterocytes: 154.6;Undifferentiated cells: 67.1;Urothelial cells: 76.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 43.6;BEWO: 28.9;CACO-2: 28.3;CAPAN-2: 56.9;HaCaT: 41.0;HBEC3-KT: 34.8;hTCEpi: 26.0;OE19: 37.3;RT4: 34.7;SK-BR-3: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.1 0.0 3.1 0.0 0.0 5.1 0.0 0.1 8.0 0.0 25.0 50.9 0.9 0.1 39.3 2.5 4.4 0.0 0.0 0.0 7.4 21.1 1.3 0.0 0.0 0.0 0.1 20.6 1.6 0.5 0.4 0.0 11.8 11.7 0.1 13.3 2.4 0.1 42.4 38.6 0.6 0.0 0.0 17.7 0.7 0.0 0.3 1.7 0.0 4.0 8.3 18.4 0.0 43.6 0.0 0.0 0.1 0.0 0.0 28.9 0.0 0.0 0.0 0.0 28.3 56.9 0.0 0.0 0.0 0.0 41.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.3 0.0 0.0 0.0 0.0 0.0 34.7 0.4 0.1 0.0 31.1 0.0 0.2 22.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 15.0 44.0 30.8 16.5 0.0 9.3 7.4 0.2 4.3 27.7 7.3 0.0 5.8 0.2 108.6 1.9 53.8 0.1 7.0 1.3 0.9 17.4 0.0 0.4 48.9 2.3 0.5 59.7 15.5 0.0 0.0 0.0 11.1 0.3 0.0 0.9 40.0 18.3 0.0 1.4 0.3 0.0 0.4 0.0 0.0 0.6 0.0 0.0 1.0 0.3 95.0 108.1 0.0 0.1 34.4 154.6 17.2 9.8 0.0 0.0 0.0 1.3 0.0 2.6 29.9 25.7 2.5 0.7 0.0 67.1 76.9 CC2D1A "FLJ20241, Freud-1, MRT3" ENSG00000132024 "Coiled-coil and C2 domain containing 1A" Q6P1N0 19 13906201-13930879 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005436, CAB015220" Supported Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli fibrillar center" "CAB015220: , HPA005436: AB_1078884" "unprognostic (8.66e-2)" "unprognostic (1.31e-2)" "unprognostic (2.55e-1)" "unprognostic (2.34e-1)" "unprognostic (1.07e-1)" "prognostic favorable (7.02e-4)" "unprognostic (7.00e-2)" "unprognostic (1.59e-3)" "unprognostic (1.17e-1)" "unprognostic (2.82e-2)" "unprognostic (2.61e-3)" "unprognostic (4.07e-2)" "unprognostic (1.23e-3)" "unprognostic (6.67e-3)" "unprognostic (1.97e-1)" "unprognostic (9.22e-2)" "unprognostic (1.71e-2)" 16.8 16.4 11.6 3.8 11.3 3.7 21.3 10.1 18.1 19.4 10.3 37.4 16.2 16.2 2.1 33.3 19.8 2.9 20.5 11.8 11.9 22.9 26.9 16.0 3.2 11.3 11.4 18.7 34.3 7.9 31.8 3.1 11.8 25.8 4.7 4.1 27.4 5.2 28.3 35.5 33.1 3.4 9.8 17.7 24.7 15.9 13.2 2.6 20.6 3.9 3.1 21.2 24.8 10.8 22.0 8.5 2.3 9.9 5.1 3.1 9.3 6.9 8.1 10.2 10.4 14.5 6.8 11.2 11.4 6.1 6.4 15.2 5.3 10.1 3.3 17.0 30.9 5.2 11.0 6.9 9.0 4.1 15.2 4.7 12.5 7.2 4.3 6.5 7.2 11.5 6.4 8.5 3.4 22.4 11.6 12.1 7.1 18.5 16.7 11.2 6.3 8.9 6.5 16.3 10.2 7.1 9.8 13.3 12.2 1.6 10.4 9.8 6.3 8.3 4.4 20.9 8.9 15.2 7.3 6.6 10.8 14.3 7.8 0.5 0.3 0.8 0.4 0.7 0.1 0.2 0.2 0.2 0.4 0.1 0.0 0.2 0.1 0.2 0.5 0.3 0.3 0.3 11.6 11.3 10.1 18.1 11.8 11.9 11.3 11.4 11.8 9.8 13.2 10.8 20.6 9.6 8.3 23.8 12.6 9.1 14.2 15.6 19.4 66.6 19.2 64.6 8.4 21.5 16.5 11.0 93.8 22.3 11.7 103.4 9.8 22.0 2.2 10.1 6.7 13.2 33.5 18.7 38.4 27.7 10.7 10.5 63.7 11.3 17.7 29.3 12.8 12.4 14.5 30.3 43.3 46.6 24.4 12.2 13.0 6.5 64.3 11.3 7.2 10.3 16.3 15.6 23.7 31.2 24.1 26.0 77.6 87.3 12.3 13.0 97.9 6.8 16.7 93.2 13.1 8.0 9.3 10.2 12.4 24.8 13.8 21.3 14.8 16.1 64.3 18.8 CCDC14 "DKFZp434L1050, FLJ12892" ENSG00000175455 "Coiled-coil domain containing 14" Q49A88 3 123897305-123961408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035278, HPA035279" Uncertain Enhanced "Centriolar satellite" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite" "HPA035278: AB_2674548, HPA035279: AB_10601253" "unprognostic (7.41e-3)" "unprognostic (5.18e-2)" "unprognostic (1.86e-1)" "unprognostic (1.41e-1)" "unprognostic (9.45e-2)" "prognostic favorable (5.27e-4)" "prognostic unfavorable (4.82e-4)" "unprognostic (6.83e-2)" "unprognostic (5.50e-2)" "unprognostic (2.12e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (4.76e-4)" "prognostic unfavorable (3.50e-8)" "unprognostic (2.14e-2)" "unprognostic (2.86e-1)" "unprognostic (9.37e-2)" "prognostic favorable (2.72e-5)" 11.8 9.6 5.3 12.8 8.5 36.6 21.4 6.4 7.5 17.1 4.6 22.5 12.8 22.1 35.5 10.0 14.5 13.6 8.6 5.1 8.7 14.4 15.3 13.7 16.6 8.8 7.5 17.4 16.8 5.6 13.7 10.6 9.0 16.3 34.8 43.2 14.9 7.9 6.2 23.8 15.4 14.2 7.7 12.4 13.9 23.7 10.1 20.5 13.2 2.9 15.0 12.0 12.4 10.0 42.6 22.5 72.1 28.0 10.6 16.1 34.0 79.9 26.2 41.6 45.2 17.5 28.5 12.4 19.9 19.1 30.1 44.5 27.1 14.8 55.9 10.5 20.0 49.9 50.7 17.7 9.0 31.2 29.9 15.1 9.7 20.7 21.9 49.0 19.7 48.9 25.8 21.0 28.1 18.3 26.4 17.3 22.2 19.0 28.0 47.2 29.0 15.2 23.3 34.1 25.4 28.3 45.2 13.0 33.4 46.5 27.5 31.2 22.9 91.1 45.8 28.5 26.5 20.0 15.8 32.8 32.2 25.6 31.5 1.1 0.6 1.3 1.4 0.9 1.0 0.8 1.2 1.2 0.3 0.7 1.3 1.1 0.1 2.5 0.2 1.8 2.6 0.7 5.3 8.5 6.4 7.5 5.1 8.7 8.8 7.5 9.0 7.7 10.1 10.0 22.1 22.4 71.5 72.8 21.3 21.9 36.4 31.2 25.6 35.9 48.9 37.7 14.6 38.6 29.4 36.8 60.5 27.5 27.6 67.9 0.0 26.1 38.6 33.7 44.0 23.8 89.7 72.1 83.8 13.8 22.9 32.3 26.0 29.9 25.9 67.9 28.5 22.3 20.9 28.6 67.7 85.6 67.1 19.7 29.9 17.3 32.6 21.0 24.9 41.2 20.1 18.6 49.4 91.0 77.1 22.8 63.7 31.2 25.3 20.4 41.6 12.6 18.9 75.5 19.7 39.2 29.4 144.0 49.6 18.2 16.1 11.6 30.3 33.5 77.7 22.9 CCDC61 ENSG00000104983 "Coiled-coil domain containing 61" Q9Y6R9 19 45995461-46021318 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Cell line enhanced" "Detected in all" "NB-4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040325, HPA061548" Uncertain Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA040325: AB_10672970, HPA061548: AB_2684559" "unprognostic (1.30e-1)" "unprognostic (1.51e-3)" "unprognostic (2.56e-1)" "unprognostic (6.23e-3)" "unprognostic (7.27e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (2.81e-1)" "unprognostic (1.58e-1)" "unprognostic (2.93e-2)" "unprognostic (2.73e-2)" "unprognostic (1.34e-1)" "unprognostic (2.13e-3)" "unprognostic (2.58e-1)" "unprognostic (2.09e-1)" "unprognostic (1.40e-2)" "unprognostic (1.09e-1)" 9.3 11.2 6.9 8.0 8.1 5.9 9.3 13.7 11.2 11.6 4.8 11.1 7.9 10.0 7.2 10.4 16.2 5.0 8.4 7.8 5.4 12.2 12.5 8.6 11.0 6.6 5.1 12.5 10.3 9.9 13.3 5.9 5.4 11.2 4.9 1.6 9.0 8.0 5.6 12.7 10.3 5.1 4.0 13.9 11.0 24.9 5.3 9.7 12.4 4.1 6.9 11.2 10.0 7.8 13.9 10.0 5.2 9.0 9.6 7.0 7.9 9.8 5.0 5.8 9.7 6.1 12.0 8.7 4.7 6.9 8.0 11.6 5.7 13.1 4.3 16.6 5.4 9.3 8.6 10.1 10.6 8.9 12.2 7.6 17.9 5.0 10.4 9.9 11.7 16.3 10.5 17.5 7.5 4.4 20.4 57.2 1.9 14.9 4.3 13.7 1.7 14.1 9.5 11.4 5.6 5.1 9.7 12.5 7.6 5.1 5.3 12.7 10.0 4.2 1.7 2.0 11.2 10.6 5.5 8.9 9.4 9.8 7.1 6.5 0.4 0.4 0.9 0.4 0.5 0.8 0.5 0.5 0.2 1.2 0.6 0.5 1.3 0.3 0.5 0.3 0.5 0.2 6.9 8.1 13.7 11.2 7.8 5.4 6.6 5.1 5.4 4.0 5.3 7.8 8.8 0.0 4.4 4.6 7.0 6.2 7.1 1.1 4.6 4.3 4.3 5.3 6.0 4.3 3.0 11.0 0.0 11.2 5.1 11.9 9.8 1.6 3.4 9.0 5.7 5.3 3.6 2.1 4.0 2.0 8.5 6.4 12.8 5.6 0.0 11.8 4.2 4.4 8.0 3.3 4.1 8.6 0.0 5.3 2.7 1.6 5.3 5.5 3.6 1.9 2.3 3.3 2.1 1.5 2.6 1.8 5.8 5.7 6.1 4.3 6.6 8.4 3.5 1.9 6.6 4.6 6.0 13.9 6.2 6.4 5.3 7.8 7.3 9.8 10.9 4.3 CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.8;placenta: 32.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 95.2;Early spermatids: 95.4;Pancreatic endocrine cells: 87.9;Paneth cells: 68.7;Proximal enterocytes: 61.1" "Cancer enhanced" "Detected in many" "stomach cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 10.8;HHSteC: 13.6;HSkMC: 14.9;RT4: 10.5;TIME: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Cytosol "HPA040865: AB_2677176, HPA048197: AB_2680310" "unprognostic (1.36e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (2.65e-2)" "unprognostic (6.29e-2)" "unprognostic (2.71e-1)" "unprognostic (1.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.77e-2)" "unprognostic (9.71e-2)" "unprognostic (6.12e-2)" "unprognostic (2.38e-1)" 5.5 3.8 1.6 4.1 1.5 0.4 3.4 1.4 2.7 4.2 2.3 18.9 20.2 3.3 0.8 1.8 2.4 5.1 5.7 1.5 3.6 2.8 9.5 13.0 0.8 2.0 2.3 15.7 2.8 0.8 3.6 32.4 2.0 4.2 18.2 0.6 1.8 1.3 1.5 0.9 24.8 2.7 1.2 7.2 14.3 8.8 3.3 0.6 2.6 4.4 1.3 2.3 1.8 1.3 10.8 3.3 0.0 0.0 3.0 8.3 0.0 0.3 4.2 0.6 0.7 5.9 6.2 0.0 7.6 0.0 0.1 0.1 0.7 6.8 0.5 0.0 1.6 0.8 3.6 1.2 13.6 0.0 0.0 14.9 0.0 3.2 0.1 0.0 4.9 0.0 0.0 0.1 0.4 0.8 0.0 0.2 0.0 7.6 3.6 0.3 0.0 0.3 1.2 10.5 0.1 2.5 3.3 1.0 0.1 1.2 0.0 0.0 28.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.6 1.5 1.4 2.7 1.5 3.6 2.0 2.3 2.0 1.2 3.3 1.3 38.5 19.2 10.3 0.3 1.0 0.3 7.4 4.8 1.2 0.1 2.0 1.9 5.5 10.0 13.3 1.8 0.0 2.3 0.3 95.2 1.9 7.2 95.4 15.0 2.5 40.8 6.0 3.6 5.7 35.6 2.7 9.6 38.2 27.1 8.8 2.6 37.5 7.0 0.4 0.0 0.5 21.8 8.2 3.2 1.3 36.7 3.4 0.6 0.0 12.2 1.0 3.3 1.0 0.0 0.1 87.9 68.7 0.7 0.0 32.4 61.1 5.3 4.2 0.2 6.6 0.9 3.0 1.2 2.2 1.1 0.0 6.0 0.4 3.8 20.2 6.4 CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 62.7;Paneth cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046825 Approved Approved "Plasma membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA046825: AB_10963934" "unprognostic (2.59e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (1.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-3)" "unprognostic (5.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-2)" "unprognostic (7.12e-3)" "unprognostic (7.99e-2)" "unprognostic (3.92e-2)" "unprognostic (8.08e-2)" "unprognostic (7.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-3)" 12.8 4.7 3.8 10.6 4.9 9.9 7.1 2.8 5.3 8.2 3.7 15.3 11.7 5.0 5.2 17.8 4.2 7.9 6.1 5.2 5.1 10.9 12.4 11.8 8.6 4.8 4.2 3.4 13.7 4.2 4.5 13.6 5.1 4.8 13.3 9.0 6.9 4.8 7.8 3.9 11.3 8.7 4.2 8.1 11.0 16.2 4.5 6.1 11.4 4.4 9.3 10.4 9.5 6.8 25.7 11.0 14.5 20.4 18.6 21.2 83.3 15.6 25.8 15.7 17.7 51.1 23.7 9.9 14.2 28.6 38.5 17.4 17.7 29.4 15.2 3.7 13.5 13.3 12.8 41.6 18.7 11.9 15.2 10.7 12.0 20.0 20.9 13.8 52.5 11.5 6.8 9.4 21.9 13.6 10.5 11.2 28.1 10.3 12.2 9.4 12.4 8.0 16.2 19.5 3.5 10.8 18.5 8.0 23.5 33.6 7.2 31.5 27.3 17.7 16.6 23.2 10.5 5.6 8.4 13.4 18.5 13.5 15.4 0.7 1.1 0.5 0.3 0.6 0.4 0.3 0.5 0.5 0.5 1.1 0.4 0.8 1.3 0.6 0.5 0.5 0.4 0.3 3.8 4.9 2.8 5.3 5.2 5.1 4.8 4.2 5.1 4.2 4.5 6.8 31.8 3.2 19.1 10.1 14.1 12.2 13.8 7.6 5.7 6.2 10.0 10.0 9.0 2.8 8.5 23.9 10.4 12.6 13.2 62.7 1.9 5.8 13.7 13.6 7.7 17.0 9.6 6.5 34.1 14.7 42.9 11.4 25.0 20.4 5.7 5.8 23.9 12.5 16.2 5.0 11.6 13.1 8.2 17.5 29.9 10.9 2.8 18.7 8.8 7.5 20.8 10.2 7.2 14.6 28.7 13.9 121.3 3.8 7.7 16.1 10.1 12.6 6.3 12.3 0.0 16.0 10.4 23.9 9.5 7.6 10.5 7.7 10.9 4.3 17.0 18.0 CD164 "DFNA66, MGC-24, MUC-24" ENSG00000135535 "CD164 molecule" Q04900 6 109366514-109382467 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010636 Uncertain "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA010636: AB_1078447" "unprognostic (1.23e-2)" "unprognostic (1.61e-2)" "unprognostic (3.89e-2)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-2)" "unprognostic (1.97e-3)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (8.88e-2)" "unprognostic (1.38e-1)" "unprognostic (7.11e-2)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.01e-1)" "unprognostic (1.51e-1)" 260.9 123.6 43.6 119.1 53.6 213.9 211.2 57.4 69.5 151.0 68.9 264.8 252.0 117.0 161.9 95.0 124.8 159.3 91.8 40.6 57.7 298.1 256.8 121.9 137.8 65.3 56.1 126.4 124.1 219.2 89.5 190.1 64.1 146.1 270.5 36.4 303.8 112.7 96.0 89.2 277.6 116.1 52.3 121.0 272.8 113.6 50.7 132.0 360.4 91.7 122.9 154.2 76.0 70.7 130.0 73.0 34.6 242.9 503.0 496.6 235.7 230.8 304.0 213.7 308.0 148.1 194.9 105.7 218.0 261.5 198.0 125.4 136.9 152.7 315.4 220.1 144.5 177.8 72.0 173.9 294.9 209.5 399.0 384.6 279.7 211.3 186.5 270.3 196.9 86.9 178.9 279.9 287.8 141.1 191.5 251.2 52.9 273.1 119.6 126.3 109.0 135.1 292.2 180.5 40.2 80.9 144.6 184.0 348.6 168.0 167.7 265.0 205.6 138.8 99.1 199.5 188.6 96.3 147.4 121.2 244.0 242.8 147.2 349.0 192.3 167.0 166.8 198.6 175.0 126.2 135.2 155.1 189.7 111.0 138.0 150.1 128.5 255.2 197.5 214.1 192.9 413.8 43.6 53.6 57.4 69.5 40.6 57.7 65.3 56.1 64.1 52.3 50.7 70.7 76.5 163.5 78.9 22.5 168.1 200.1 180.2 149.6 128.7 33.8 251.1 123.3 70.9 174.5 153.5 281.4 25.0 244.9 372.7 600.0 93.9 178.8 103.8 111.9 109.2 89.2 166.5 92.8 22.1 136.8 407.2 176.3 175.8 151.2 128.6 76.7 98.2 177.4 311.9 33.7 16.4 427.3 215.7 360.4 223.9 97.3 158.8 237.3 247.3 38.4 147.1 113.3 266.8 15.6 83.1 177.6 430.0 182.1 173.6 230.3 425.5 348.0 351.2 44.4 124.9 110.0 138.1 160.5 184.4 143.0 231.0 674.5 165.9 87.7 285.0 334.7 CD177 "HNA2A, NB1, PRV1" ENSG00000204936 "CD177 molecule" 19 43353686-43363172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9;intestine: 164.6" "Group enriched" "Detected in some" 5 "Distal enterocytes: 632.4;Paneth cells: 314.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.6" "Group enriched" "Detected in many" 4 "cerebellum: 3.6;cerebral cortex: 7.7;pons: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 98.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041820, HPA046601, HPA077640" Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041820: AB_2677691, HPA046601: AB_2679716, HPA077640: " "unprognostic (4.32e-2)" "prognostic favorable (3.66e-4)" "unprognostic (1.04e-2)" "unprognostic (2.04e-3)" "unprognostic (1.61e-1)" "unprognostic (3.89e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (2.05e-1)" "unprognostic (1.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.90e-2)" "unprognostic (2.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (1.24e-1)" 4.8 0.4 0.1 7.2 0.3 285.9 1.3 3.6 7.7 6.0 3.7 155.2 0.3 0.4 0.2 2.2 2.3 0.2 2.2 0.3 0.1 1.9 2.6 20.6 0.2 0.3 1.0 0.3 1.1 0.0 2.9 1.6 2.3 64.8 164.6 0.1 1.8 0.2 0.7 0.4 0.7 3.0 0.3 64.4 1.4 0.2 0.4 1.4 0.7 0.8 10.4 2.1 5.4 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.3 1.0 1.3 0.6 0.6 0.0 0.0 0.1 2.4 0.6 1.7 0.2 0.1 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 1.2 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.4 1.2 0.0 0.2 0.0 0.0 98.0 1.4 0.3 0.7 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.3 2.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 1.2 0.0 0.7 0.0 0.1 0.3 3.6 7.7 0.3 0.1 0.3 1.0 2.3 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 632.4 0.0 0.5 0.4 0.2 0.1 0.0 8.4 3.6 0.0 0.2 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 87.2 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 314.8 0.0 0.1 29.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 28.0 0.2 CD2AP CMS ENSG00000198087 "CD2 associated protein" Q9Y5K6 6 47477789-47627263 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 204.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003267, HPA003326, CAB004352" Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 58000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Centriolar satellite" "CAB004352: AB_627009, HPA003267: AB_1078458, HPA003326: AB_1078457" "unprognostic (5.98e-2)" "unprognostic (1.08e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "unprognostic (1.77e-2)" "unprognostic (1.74e-3)" "unprognostic (1.19e-1)" "unprognostic (6.71e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (2.21e-1)" "unprognostic (3.09e-3)" "unprognostic (6.12e-3)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "prognostic favorable (7.57e-5)" 14.0 10.5 3.4 15.0 3.4 14.3 17.8 6.3 4.6 18.1 8.8 40.0 56.9 12.0 13.2 19.2 14.1 15.0 7.7 2.7 3.8 34.1 20.2 17.1 15.9 4.3 3.9 6.4 20.2 35.6 6.0 21.6 4.7 19.7 36.9 6.9 17.0 13.5 6.9 18.0 59.5 10.9 4.3 13.7 40.4 9.4 3.9 34.0 18.2 10.3 17.4 30.1 10.1 4.6 58.0 22.5 6.9 14.3 9.4 13.6 54.8 13.9 16.9 18.5 23.3 37.3 39.9 74.5 56.9 18.2 24.0 21.2 23.0 34.7 29.9 29.9 37.2 41.3 18.4 33.6 12.5 23.3 15.4 9.7 32.1 17.7 25.5 35.7 30.1 24.4 73.5 23.2 16.9 18.2 44.6 8.7 20.3 69.6 8.1 23.6 17.6 34.1 115.6 101.7 20.9 8.1 27.9 36.9 27.7 31.1 35.0 14.8 36.2 36.9 30.8 12.0 39.9 17.5 31.3 52.6 39.4 12.4 19.2 1.8 0.5 3.2 1.2 0.4 1.8 0.9 1.0 1.1 1.2 1.0 0.9 1.5 0.1 3.1 0.4 9.9 0.9 0.5 3.4 3.4 6.3 4.6 2.7 3.8 4.3 3.9 4.7 4.3 3.9 4.6 81.7 96.1 67.1 32.0 40.5 32.2 52.1 26.5 39.9 10.0 40.4 26.4 17.2 35.8 68.9 71.7 16.7 53.0 96.1 204.1 21.5 84.6 10.4 97.9 25.0 56.6 55.8 42.9 40.7 98.0 17.1 20.6 101.4 136.7 24.1 28.5 37.5 24.2 17.4 15.2 45.3 97.3 40.7 26.2 12.6 10.5 16.8 30.6 14.2 83.4 18.0 12.5 22.6 28.6 30.8 151.3 114.0 10.9 27.7 89.0 182.3 67.4 60.0 13.0 26.3 34.9 27.8 38.9 27.2 44.2 41.1 40.9 29.4 48.0 68.8 143.6 CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20589086-20618903 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 193.5;esophagus: 87.1;liver: 86.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 364.9;Hepatocytes: 107.8;Pancreatic endocrine cells: 120.2;Paneth cells: 400.5;Proximal enterocytes: 137.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1234.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 1234.7" "Cell line enhanced" "Detected in many" "A-431: 200.3;CAPAN-2: 141.9;HeLa: 207.1;PC-3: 107.0;SiHa: 249.9;U-937: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA064202 Enhanced Approved Nucleoplasm NA NA 3700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA064202: AB_2685211" "unprognostic (2.38e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (8.02e-2)" "unprognostic (3.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.68e-3)" "unprognostic (2.64e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (8.56e-5)" "unprognostic (2.94e-2)" "unprognostic (5.03e-2)" "unprognostic (8.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.89e-3)" 7.1 3.0 8.0 9.6 8.1 193.5 3.7 8.3 10.6 19.7 7.4 23.7 6.4 5.3 5.5 87.1 6.4 4.3 6.7 7.9 8.3 14.0 86.7 7.1 1.5 9.0 8.2 1.5 0.8 3.2 1.2 10.8 9.5 4.3 27.8 0.5 15.0 3.1 1.7 17.1 16.3 11.3 8.3 23.4 2.1 1.0 8.9 2.0 4.5 6.4 4.4 5.5 38.5 8.7 200.3 21.4 0.0 0.0 0.2 5.5 0.0 16.7 4.3 4.1 16.2 1.0 141.9 0.0 8.1 30.8 8.7 63.9 4.5 46.8 10.7 0.1 3.9 0.0 207.1 34.4 1.4 0.0 0.0 8.8 8.9 31.4 0.0 0.5 2.7 0.0 0.0 0.0 1.6 0.2 0.0 1.0 0.1 24.7 107.0 0.0 0.1 3.4 1.5 0.0 0.1 0.0 249.9 0.0 0.3 2.2 0.0 4.3 3.4 0.2 8.3 18.5 1.2 0.0 0.1 0.0 2.4 96.9 0.0 216.2 207.2 471.1 0.5 124.7 0.8 0.1 0.4 0.9 12.7 0.2 0.3 0.4 1234.7 0.4 110.8 3.1 0.7 86.8 8.0 8.1 8.3 10.6 7.9 8.3 9.0 8.2 9.5 8.3 8.9 8.7 9.9 3.2 1.1 0.3 1.2 1.5 0.1 2.4 0.0 0.2 0.2 0.3 2.6 1.5 2.7 5.5 0.0 1.1 0.0 364.9 43.0 7.5 0.8 2.1 2.6 42.7 0.0 6.1 0.2 1.5 6.4 9.1 0.0 20.3 0.0 0.0 47.2 107.8 5.9 0.0 0.3 23.1 85.5 60.7 0.9 1.0 0.3 36.6 0.0 5.6 61.5 0.1 0.0 0.5 0.0 120.2 400.5 0.0 3.0 2.1 137.6 0.6 0.4 0.1 0.0 1.3 1.3 0.0 1.2 6.3 1.1 2.5 1.7 0.0 19.8 0.8 CDC42EP5 "Borg3, CEP5" ENSG00000167617 "CDC42 effector protein 5" Q6NZY7 19 54465026-54473296 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 83.8;prostate: 60.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 435.6;Intestinal goblet cells: 547.3;Paneth cells: 288.4;Prostatic glandular cells: 193.3;Undifferentiated cells: 257.0;Urothelial cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 8.4;BJ hTERT+: 5.9;CAPAN-2: 6.5;EFO-21: 9.6;HHSteC: 6.6;TIME: 8.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043449 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA043449: AB_10961041" "unprognostic (7.67e-2)" "unprognostic (1.24e-3)" "unprognostic (9.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.86e-1)" "unprognostic (1.90e-1)" "unprognostic (3.36e-1)" "unprognostic (7.30e-3)" "unprognostic (1.63e-1)" "unprognostic (2.52e-2)" "unprognostic (6.49e-2)" "unprognostic (4.13e-2)" "prognostic unfavorable (2.79e-5)" "unprognostic (1.73e-2)" "unprognostic (5.41e-2)" "unprognostic (6.37e-3)" "prognostic favorable (1.36e-4)" 24.3 8.1 0.7 0.2 0.6 0.0 23.4 0.5 1.1 26.2 0.6 83.8 18.4 13.6 0.0 16.7 16.9 0.8 19.0 0.5 0.4 13.5 3.4 24.1 0.4 1.8 0.4 12.7 14.5 0.1 5.5 1.4 1.1 60.4 4.4 0.1 40.1 2.1 3.8 11.4 52.4 0.4 0.3 9.2 19.6 6.0 0.6 0.2 11.0 0.5 0.3 42.5 22.9 0.9 0.0 0.0 0.7 0.4 0.7 4.8 3.3 8.4 5.9 0.4 0.1 1.4 6.5 0.0 9.6 2.2 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.9 0.1 0.0 0.4 1.5 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.7 0.1 2.2 0.1 3.8 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 8.9 0.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.5 1.1 0.5 0.4 1.8 0.4 1.1 0.3 0.6 0.9 123.5 0.0 0.0 0.3 1.3 10.3 75.4 2.3 13.1 0.9 107.8 114.7 1.3 0.0 2.4 18.4 0.0 0.4 2.3 435.6 0.0 3.1 6.4 4.3 37.0 50.7 39.0 0.0 0.5 11.4 12.6 33.8 50.0 5.0 8.9 0.8 61.1 0.3 0.8 0.0 0.2 547.3 0.0 1.9 5.9 12.0 10.2 1.5 17.8 7.5 0.6 26.7 0.0 0.0 0.5 11.2 288.4 9.1 0.0 193.3 117.0 0.3 0.4 2.5 6.6 3.8 17.6 0.5 1.2 18.3 7.5 0.7 2.4 17.3 257.0 385.7 CDCA7 "FLJ14736, JPO1" ENSG00000144354 "Cell division cycle associated 7" Q9BWT1 2 173354820-173368997 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.4;lymphoid tissue: 50.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.7;Intestinal goblet cells: 40.7;Leydig cells: 53.7;Undifferentiated cells: 124.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 43.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 7.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MOLT-4: 279.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005565 Supported Nucleoplasm,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA005565: AB_2078680" "unprognostic (1.67e-3)" "unprognostic (2.26e-1)" "unprognostic (1.21e-1)" "unprognostic (1.54e-2)" "unprognostic (2.16e-1)" "unprognostic (1.44e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (7.54e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.96e-2)" "unprognostic (2.83e-1)" "unprognostic (8.97e-3)" "unprognostic (0.00e+0)" "unprognostic (4.53e-3)" "unprognostic (1.96e-1)" "unprognostic (2.04e-1)" "unprognostic (2.47e-2)" 1.7 0.3 0.7 13.1 0.6 23.0 2.4 0.5 0.7 12.6 6.5 25.5 30.7 13.8 3.3 10.1 3.8 1.5 0.8 0.7 1.2 0.5 0.3 1.6 37.5 0.7 0.9 1.1 1.7 0.3 0.1 7.4 0.7 3.0 29.5 0.4 2.5 1.2 3.1 11.7 32.4 3.4 0.7 2.4 14.3 6.0 1.2 50.1 0.5 0.8 41.2 2.8 6.7 1.0 44.2 33.3 76.4 83.3 3.6 14.0 79.9 26.0 9.2 60.3 67.2 51.6 54.4 122.1 32.2 15.8 23.5 45.0 122.4 46.6 87.0 59.2 67.4 27.6 24.6 66.0 3.8 181.2 25.1 11.4 3.9 32.8 27.3 7.8 28.0 158.1 67.4 27.2 17.7 35.4 279.7 181.7 90.4 103.4 22.7 194.4 58.2 77.3 29.5 38.2 22.3 39.2 40.8 13.4 22.0 67.9 0.3 70.5 13.0 39.3 16.8 12.9 48.5 7.4 17.1 173.0 24.4 99.8 34.0 0.0 0.5 0.0 1.1 0.0 0.4 1.9 3.0 5.9 3.5 0.3 0.2 1.0 0.2 3.2 0.0 0.5 7.9 2.3 0.7 0.6 0.5 0.7 0.7 1.2 0.7 0.9 0.7 0.7 1.2 1.0 1.0 0.0 0.6 0.7 3.0 20.3 14.9 3.3 14.8 0.0 2.6 6.5 1.1 0.0 0.3 0.0 0.0 45.7 1.6 17.1 0.0 0.2 0.9 3.2 33.0 3.4 12.2 33.6 0.1 0.2 29.9 4.1 22.4 6.8 0.0 18.5 0.0 0.2 10.4 0.0 10.5 40.7 4.1 1.0 4.4 2.2 53.7 2.3 3.6 0.0 1.2 0.7 0.0 0.5 0.1 1.0 11.1 34.6 3.8 5.3 11.9 0.0 0.1 0.0 0.0 1.1 7.2 13.8 28.9 21.8 15.9 10.1 9.1 2.7 124.2 3.8 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH17 "cadherin, HPT-1" ENSG00000079112 "Cadherin 17" Q12864 8 94127162-94217303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "intestine: 314.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 569.4;Enteroendocrine cells: 108.4;Intestinal goblet cells: 183.7;Paneth cells: 408.6;Proximal enterocytes: 336.9;Undifferentiated cells: 241.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 156.4;stomach cancer: 54.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 16.0" "Lineage enriched" "Detected in single" 17 "granulocytes: 16.0" "Cell line enhanced" "Detected in some" "CACO-2: 98.8;OE19: 430.1;U-266/70: 157.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023614, HPA023616, CAB025143, HPA026556" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA 7500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB025143: , HPA023614: AB_1845896, HPA023616: AB_1845895, HPA026556: AB_1845897" "unprognostic (2.08e-1)" "unprognostic (5.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (3.06e-2)" "unprognostic (5.60e-2)" "unprognostic (3.38e-3)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.47e-2)" "unprognostic (3.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (7.33e-2)" "unprognostic (1.46e-2)" 0.9 0.2 0.7 28.8 0.5 2.7 0.5 1.1 0.8 0.1 1.9 260.9 314.2 1.3 0.8 1.7 0.3 3.0 0.6 0.5 0.2 0.8 0.3 0.2 1.5 0.3 0.1 0.5 1.7 0.0 0.0 0.2 0.3 1.2 246.7 0.5 0.9 1.6 0.5 0.6 270.6 9.3 0.1 5.5 2.5 0.6 0.2 0.3 0.7 0.1 1.8 0.8 0.1 0.7 0.2 18.5 0.2 0.4 0.0 0.4 1.6 0.2 0.3 0.2 0.3 98.8 3.5 0.3 0.3 0.0 0.1 1.0 0.3 0.3 0.3 0.2 1.1 0.1 0.8 0.6 0.3 0.2 4.3 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.4 1.5 0.1 0.7 0.5 1.3 0.3 430.1 0.5 0.3 0.0 2.8 0.3 0.2 1.3 1.2 0.4 0.4 0.5 0.4 0.7 0.9 0.0 0.6 0.7 1.2 0.5 157.2 0.3 0.2 0.3 0.3 0.6 2.9 0.9 1.4 0.2 0.8 0.1 0.3 0.2 0.1 0.5 0.8 0.2 0.3 16.0 0.7 0.5 0.4 0.2 0.2 0.7 0.5 1.1 0.8 0.5 0.2 0.3 0.1 0.3 0.1 0.2 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 569.4 0.0 0.3 1.0 0.0 0.0 0.0 108.4 0.0 0.5 0.0 0.0 0.1 2.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 183.7 0.0 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 408.6 0.0 0.2 0.0 336.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 2.1 0.0 241.6 0.1 CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.2;intestine: 30.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 240.7;Pancreatic endocrine cells: 164.5;Proximal enterocytes: 139.0;Squamous epithelial cells: 142.0;Urothelial cells: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.1;HaCaT: 35.0;HeLa: 33.9;hTERT-RPE1: 60.1;SiHa: 48.0;SK-MEL-30: 35.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB000349: , HPA052838: , HPA063327: AB_2684987" "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" 18.7 1.9 2.0 2.9 1.8 0.4 8.6 1.1 1.9 9.6 9.1 22.4 21.7 3.8 0.6 36.2 1.7 2.4 1.0 1.6 2.2 1.2 1.2 12.6 1.1 2.7 1.5 0.9 1.2 3.3 3.5 2.3 2.3 3.6 19.7 2.8 6.7 4.7 7.2 12.9 30.9 2.1 1.7 4.6 6.0 5.3 2.4 0.8 1.1 1.1 8.1 7.9 20.2 2.4 0.0 0.0 0.3 2.1 28.2 38.1 0.7 1.8 0.0 4.6 12.6 3.6 10.3 0.0 3.4 2.3 0.0 35.0 0.8 6.9 5.5 2.6 9.7 0.0 33.9 1.5 14.4 1.1 6.1 8.1 0.0 6.5 25.8 60.1 4.4 0.0 0.0 17.1 7.3 2.8 0.0 0.1 1.7 1.7 19.5 0.0 2.4 0.7 10.0 0.0 5.4 0.1 48.0 11.5 35.7 25.8 3.0 0.0 14.8 0.0 0.7 0.1 0.0 13.5 8.4 0.1 0.0 1.0 0.0 0.0 3.3 0.0 0.1 3.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.0 9.0 0.0 0.0 1.0 2.0 1.8 1.1 1.9 1.6 2.2 2.7 1.5 2.3 1.7 2.4 2.4 3.5 67.3 6.7 0.3 2.9 5.4 27.0 40.5 5.7 3.2 6.4 9.8 3.1 1.5 37.5 5.5 0.0 1.2 3.2 240.7 0.0 57.7 11.3 31.8 7.5 4.1 7.7 0.0 0.1 38.2 0.8 11.5 30.5 37.2 0.0 0.4 1.8 0.1 1.2 0.0 0.5 31.6 14.2 17.6 3.8 2.7 0.6 5.6 3.6 2.8 3.2 4.8 0.0 1.0 0.5 164.5 75.6 1.2 2.1 65.3 139.0 0.1 17.9 7.2 0.0 2.7 8.9 13.8 3.5 142.0 24.2 3.1 2.9 1.2 23.3 241.6 CDX1 ENSG00000113722 "Caudal type homeobox 1" P47902 5 150166778-150184558 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 131.3" "Group enriched" "Detected in some" 4 "Distal enterocytes: 349.6;Intestinal goblet cells: 193.4;Paneth cells: 295.0;Proximal enterocytes: 196.8;Undifferentiated cells: 312.5" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 125.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 6.7;SuSa: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA055196 Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055196: AB_2682734" "unprognostic (2.50e-3)" "unprognostic (3.90e-1)" "unprognostic (1.65e-2)" "unprognostic (1.09e-2)" "unprognostic (5.89e-2)" "unprognostic (1.54e-2)" "unprognostic (2.07e-2)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (7.20e-2)" "unprognostic (1.59e-1)" "unprognostic (2.96e-1)" "unprognostic (1.83e-7)" "unprognostic (2.10e-1)" "unprognostic (4.25e-1)" "unprognostic (5.42e-3)" "unprognostic (2.16e-3)" 0.3 0.0 0.1 9.6 0.1 0.0 0.7 0.1 0.4 0.7 0.1 131.3 63.9 0.5 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 1.2 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 124.4 0.0 0.1 0.5 0.0 0.3 94.5 5.2 0.1 0.1 0.5 2.4 0.2 0.1 0.1 0.0 1.7 0.2 0.4 0.2 0.0 0.0 0.0 0.0 1.0 0.5 0.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 349.6 0.0 0.0 0.1 0.0 0.5 0.1 59.5 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.4 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 295.0 1.5 0.0 0.0 196.8 0.2 0.0 0.0 0.0 0.0 1.6 2.8 15.3 0.0 0.3 0.1 0.8 0.1 312.5 0.0 CDX2 CDX3 ENSG00000165556 "Caudal type homeobox 2" Q99626 13 27960918-27969315 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 41.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 287.5;Intestinal goblet cells: 214.5;Paneth cells: 181.7;Proximal enterocytes: 226.9;Undifferentiated cells: 194.4" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 63.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 14.4;CAPAN-2: 4.8;HEK 293: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002221, HPA045669, HPA049580" Enhanced Enhanced Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB002221: AB_563649, HPA045669: AB_2679413, HPA049580: AB_2680823" "unprognostic (1.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.92e-1)" "unprognostic (8.11e-3)" "unprognostic (4.19e-6)" "unprognostic (1.73e-4)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" "unprognostic (5.51e-2)" "unprognostic (6.07e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" 0.1 0.0 0.0 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.0 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 31.3 0.0 0.0 0.1 0.0 0.0 35.9 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.4 4.8 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 7.7 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 3.0 0.0 287.5 0.0 28.9 0.0 0.0 0.0 0.0 62.4 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 214.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.9 181.7 0.0 0.0 0.2 226.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.3 0.4 0.0 194.4 0.3 CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "CEA cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 246.3" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 335.2;Distal enterocytes: 731.7;Paneth cells: 585.4;Prostatic glandular cells: 244.9;Urothelial cells: 618.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 43.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "eosinophil: 43.6;neutrophil: 26.3" "Lineage enriched" "Detected in many" 13 "granulocytes: 43.6" "Group enriched" "Detected in many" 5 "CAPAN-2: 30.6;Hep G2: 101.0;OE19: 80.9;RT4: 59.2;SK-MEL-30: 67.4" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" NA NA 130000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB002146: AB_563614, HPA011041: AB_1078481" "unprognostic (7.13e-3)" "unprognostic (2.15e-1)" "unprognostic (2.67e-2)" "prognostic favorable (6.32e-7)" "unprognostic (3.04e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (4.45e-2)" "unprognostic (4.43e-1)" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (4.03e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (7.55e-2)" "unprognostic (5.52e-3)" 11.9 10.6 1.3 31.1 0.8 74.5 13.3 3.2 1.8 16.4 0.0 246.3 53.3 11.1 3.9 64.9 6.0 7.4 4.0 1.9 0.0 31.9 60.5 6.8 4.3 0.4 0.1 1.1 2.4 1.7 3.8 33.1 0.5 20.2 141.2 0.6 58.9 10.3 2.7 3.3 51.0 13.1 0.0 7.9 19.9 3.7 0.2 2.3 3.1 3.1 21.5 37.0 29.2 0.0 0.6 5.6 0.3 0.3 0.0 0.0 14.4 0.0 0.2 1.0 0.5 2.3 30.6 1.7 12.2 0.0 3.2 0.8 0.0 7.9 0.4 0.1 0.5 0.3 0.2 101.0 1.7 0.2 13.3 0.0 0.1 0.1 0.1 0.0 0.7 1.4 0.0 5.0 0.0 3.2 0.3 0.2 0.9 80.9 1.7 2.6 0.0 1.3 0.6 59.2 0.5 0.2 0.0 0.2 67.4 7.3 0.3 0.0 2.1 0.3 1.2 1.4 0.5 1.8 0.0 3.7 0.2 0.4 1.0 0.8 0.0 43.6 0.1 1.7 0.3 3.3 0.9 0.4 0.2 0.8 0.6 0.2 26.3 0.1 3.3 0.1 2.7 0.6 1.3 0.8 3.2 1.8 1.9 0.0 0.4 0.1 0.5 0.0 0.2 0.0 16.7 6.4 8.2 1.0 6.0 1.3 335.2 10.4 2.8 6.0 16.3 12.7 1.8 7.2 14.7 0.0 4.2 2.0 0.7 731.7 0.0 21.3 3.5 5.0 5.2 22.3 17.3 0.4 1.7 16.1 9.4 2.9 12.8 28.7 8.9 4.6 41.4 37.7 1.4 5.0 1.4 46.1 4.1 5.9 3.1 0.2 0.0 2.6 7.2 0.0 0.9 1.3 2.1 0.5 0.6 58.7 585.4 0.7 0.2 244.9 97.5 11.1 3.9 6.4 0.0 2.7 3.1 4.3 3.9 9.2 1.0 0.7 5.5 2.2 33.2 618.9 CEACAM3 "CD66d, CGM1" ENSG00000170956 "CEA cell adhesion molecule 3" P40198 19 41796587-41811554 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 44.3" "Cell type enriched" "Detected in some" 13 "Paneth cells: 56.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 6 "neutrophil: 289.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 289.3" "Not detected" "Not detected" HPA011041 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA011041: AB_1078481" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (8.09e-3)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (1.49e-1)" "unprognostic (3.19e-2)" "unprognostic (1.62e-1)" "unprognostic (8.07e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-1)" "unprognostic (4.68e-2)" "unprognostic (8.44e-2)" "unprognostic (2.83e-1)" 0.9 0.1 0.0 5.1 0.0 44.3 0.1 0.0 0.9 0.3 0.3 0.3 0.0 0.2 0.0 0.4 0.3 0.3 0.3 0.0 0.0 0.1 0.6 1.8 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.0 5.1 0.1 0.0 0.0 0.6 0.1 1.2 0.4 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 4.2 0.0 0.0 19.3 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 289.3 0.0 45.8 0.0 0.0 3.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.8 0.0 0.0 0.3 0.0 3.3 0.0 1.4 0.0 4.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 56.4 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.4 0.4 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 181.5;esophagus: 195.2;intestine: 220.3;lung: 286.7;salivary gland: 177.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 942.3;Club cells: 322.1;Distal enterocytes: 640.1;Paneth cells: 391.1;Urothelial cells: 182.3" "Group enriched" "Detected in many" 4 "cervical cancer: 139.4;colorectal cancer: 500.8;lung cancer: 344.1;pancreatic cancer: 437.5;stomach cancer: 231.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 11 "OE19: 1799.0" "CAB008370, HPA011041" Enhanced NA NA 86000000 "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB008370: AB_592067, HPA011041: AB_1078481" "unprognostic (1.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.42e-4)" "unprognostic (4.08e-1)" "unprognostic (8.71e-3)" "unprognostic (2.85e-1)" "unprognostic (7.68e-2)" 2.0 0.4 0.3 29.7 1.2 181.5 2.7 0.6 0.6 39.2 0.0 195.0 33.0 0.6 1.8 195.2 8.2 130.1 0.2 0.2 0.0 0.3 0.7 286.7 0.3 0.3 0.1 0.4 5.2 0.1 0.3 0.5 0.2 2.4 220.3 0.0 177.6 1.4 0.1 6.8 24.4 6.6 0.0 2.4 15.5 0.4 0.3 2.1 0.3 0.0 32.5 9.6 79.1 0.4 0.1 162.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 5.5 4.6 0.0 0.2 0.0 0.5 19.4 0.0 0.0 0.1 0.3 0.2 0.0 0.5 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.1 11.2 0.1 0.2 0.2 1799.0 4.5 0.1 0.0 0.1 1.0 0.7 1.8 0.1 0.0 4.2 0.0 0.2 0.6 1.9 0.4 0.2 0.3 0.5 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.5 0.1 0.0 3.1 0.3 1.2 0.6 0.6 0.2 0.0 0.3 0.1 0.2 0.0 0.3 0.4 0.0 942.3 84.5 0.0 2.3 0.0 4.9 17.9 0.0 0.0 3.5 2.0 0.2 75.8 322.1 0.0 0.0 0.0 0.0 640.1 0.0 77.0 0.2 0.4 0.1 1.3 5.4 0.0 0.1 16.3 0.0 1.3 1.5 0.8 7.0 0.0 0.4 0.3 0.0 0.0 0.1 102.3 14.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.7 391.1 0.0 0.0 24.2 5.7 0.0 71.8 0.0 0.0 0.0 9.9 0.0 0.1 15.6 0.0 0.0 1.2 0.0 31.7 182.3 CEACAM7 "CEA, CGM2" ENSG00000007306 "CEA cell adhesion molecule 7" Q14002 19 41673303-41706976 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 651.8" "Group enriched" "Detected in some" 9 "Distal enterocytes: 1454.0;Paneth cells: 731.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 66.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA069621, HPA073910" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "HPA069621: AB_2686162, HPA073910: " "unprognostic (5.24e-2)" "unprognostic (2.72e-1)" "unprognostic (1.64e-2)" "unprognostic (6.03e-2)" "unprognostic (2.07e-2)" "unprognostic (4.30e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.14e-1)" 0.6 0.0 0.0 71.4 0.0 0.1 2.9 0.0 0.0 13.3 0.0 595.8 0.5 0.3 0.0 52.6 0.6 39.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.4 651.8 0.0 4.0 0.8 0.1 1.4 0.7 5.7 0.0 0.2 2.0 0.1 0.0 0.0 0.0 0.0 12.0 23.4 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.9 0.0 0.0 0.1 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 1454.0 0.0 116.6 0.1 0.0 0.0 0.5 8.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 1.0 731.2 0.0 0.0 1.4 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 38.4 30.3 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cell line enhanced" "Detected in many" "BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 98.7 2.9 16.2 5.7 17.9 22.6 67.7 18.3 26.9 8.7 10.4 21.0 21.2 2.9 0.8 20.9 4.3 3.0 2.8 15.7 18.8 3.6 194.7 25.5 9.1 27.4 22.4 1.3 9.7 26.8 2.6 16.0 21.3 8.8 11.5 0.6 9.8 3.4 19.1 118.7 20.8 2.5 25.7 7.7 12.5 1.0 24.5 4.1 6.5 4.5 6.3 8.7 14.8 34.8 2.5 5.1 0.1 7.1 55.8 0.0 196.9 0.1 1.5 0.1 0.0 24.8 0.1 0.0 3.0 0.0 1.1 9.4 5.8 0.6 0.0 35.8 7.2 0.1 0.1 110.9 0.9 36.6 42.1 2.2 25.4 0.0 0.2 0.0 0.0 2.8 2.4 0.0 0.0 12.7 0.2 114.1 5.0 61.8 2.7 0.0 0.4 1.1 0.2 17.7 0.4 1.7 0.7 0.5 0.8 6.2 13.7 407.7 0.1 0.1 0.8 0.1 0.9 0.4 0.0 0.2 0.0 130.9 0.0 16.0 7.1 0.0 0.8 12.3 0.7 0.0 0.1 0.5 5.1 0.1 0.2 0.4 2.5 0.0 15.7 0.2 0.0 2.1 16.2 17.9 18.3 26.9 15.7 18.8 27.4 22.4 21.3 25.7 24.5 34.8 5.4 16.0 37.8 0.0 2.8 37.3 20.8 3.3 22.2 0.7 6.2 12.2 0.4 57.2 5.1 0.0 0.0 40.3 14.4 91.6 3.9 0.5 0.0 0.8 0.8 4.9 4.2 5.7 1.9 5.8 44.3 9.5 12.8 1.3 1.3 0.0 2.2 106.5 87.0 0.0 0.3 24.8 4.1 35.0 27.4 0.2 3.1 42.9 5.4 17.8 28.2 8.4 6.2 1.0 0.4 1.9 30.6 1.5 2.0 15.1 42.5 4.9 5.1 0.5 0.0 4.1 3.1 0.2 0.7 29.7 171.8 212.3 5.0 0.3 51.5 12.2 CEBPG "GPE1BP, IG/EBP-1" ENSG00000153879 "CCAAT enhancer binding protein gamma" P53567 19 33373685-33382686 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012024 Enhanced Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA012024: AB_1846503" "unprognostic (5.56e-2)" "unprognostic (1.35e-1)" "unprognostic (3.29e-3)" "prognostic unfavorable (7.97e-5)" "unprognostic (8.12e-2)" "unprognostic (2.35e-2)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (1.16e-1)" "unprognostic (5.25e-2)" "unprognostic (8.87e-2)" "unprognostic (2.01e-2)" 19.1 8.8 16.0 14.2 16.9 15.4 15.1 17.6 23.8 11.0 12.4 30.2 34.1 12.0 9.1 20.1 11.9 11.4 14.8 15.6 19.3 12.9 34.6 16.0 12.4 17.0 17.6 5.3 28.3 15.1 11.0 16.8 17.6 12.0 28.8 17.3 13.5 9.4 47.4 27.7 35.3 14.6 18.7 9.7 18.8 12.5 19.0 14.1 25.7 44.2 13.8 16.3 14.2 18.4 33.4 29.7 30.9 31.0 14.8 21.6 41.8 24.8 22.1 21.9 26.4 35.3 14.4 54.0 19.1 11.8 26.2 16.6 54.8 25.0 37.5 91.7 23.3 29.1 15.6 34.5 49.3 49.1 31.0 28.6 121.0 27.7 86.7 11.1 27.7 45.1 39.3 49.7 17.9 20.4 33.0 25.7 17.5 94.2 18.2 35.1 21.0 22.5 12.4 19.9 61.1 37.2 25.8 26.7 61.3 22.6 22.7 96.8 26.7 22.2 26.3 23.8 39.6 28.4 27.0 32.4 23.4 53.2 31.4 7.5 9.7 4.4 3.6 11.8 4.3 4.6 4.9 5.6 10.3 3.7 5.2 5.0 0.8 3.0 19.1 3.2 6.0 5.6 16.0 16.9 17.6 23.8 15.6 19.3 17.0 17.6 17.6 18.7 19.0 18.4 61.3 19.2 13.2 2.6 30.5 124.3 95.8 51.5 67.7 11.3 32.8 31.9 15.1 48.6 29.6 14.7 8.4 42.6 27.6 160.5 19.6 37.0 90.3 43.2 14.9 50.4 35.3 22.3 11.7 54.1 71.5 26.1 34.1 26.6 26.0 9.5 31.4 66.2 45.6 3.3 8.3 81.8 34.6 35.4 65.1 74.5 6.8 34.4 28.4 10.3 63.9 27.7 28.8 6.0 3.9 75.8 107.7 9.1 30.5 70.2 115.7 30.4 49.4 12.9 6.6 24.7 31.5 76.4 45.2 57.8 155.7 74.8 29.4 5.1 67.8 120.4 CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 100.4;Spermatogonia: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 106.4;JURKAT: 105.1;NTERA-2: 103.4" "Low region specificity" "Detected in all" "HPA042529, HPA042616" Enhanced Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Midbody, Cytosol" "HPA042529: AB_10793882, HPA042616: AB_10794050" "unprognostic (7.64e-2)" "unprognostic (4.41e-2)" "unprognostic (5.92e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (6.47e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-2)" "unprognostic (7.73e-3)" "unprognostic (7.93e-2)" "unprognostic (4.09e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-2)" "unprognostic (2.54e-2)" "unprognostic (3.60e-3)" 4.0 4.7 11.7 0.6 11.3 5.1 4.6 9.3 11.7 4.4 7.1 9.1 9.8 5.9 3.5 0.5 6.6 1.3 5.6 11.9 13.2 3.4 10.7 2.6 1.2 11.6 11.0 6.2 4.0 3.9 7.0 1.2 10.0 3.1 8.0 4.0 1.5 4.0 21.1 0.8 10.6 4.0 11.6 1.1 13.2 10.3 11.4 17.1 2.4 9.5 1.2 4.2 1.7 11.9 10.7 20.4 106.4 53.4 3.0 2.7 18.2 8.7 8.6 26.5 20.0 20.5 4.7 42.5 17.0 6.5 4.9 3.2 69.3 0.6 16.8 0.0 85.9 10.1 5.0 41.1 29.2 10.1 0.0 7.6 2.8 31.6 18.7 3.0 15.2 105.1 17.4 0.0 8.0 1.8 80.2 34.2 103.4 69.1 0.0 57.1 4.1 4.9 6.1 15.4 56.8 43.9 22.2 0.3 5.2 48.6 0.3 24.8 1.0 0.0 8.6 1.2 0.0 0.0 0.0 24.9 0.0 14.0 0.6 0.0 0.0 1.3 0.1 0.0 0.0 1.4 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.7 11.3 9.3 11.7 11.9 13.2 11.6 11.0 10.0 11.6 11.4 11.9 13.3 0.0 2.7 3.9 13.7 1.0 29.7 0.5 4.6 40.0 22.5 31.6 4.2 30.0 4.4 1.8 4.2 19.6 19.6 43.0 31.3 7.5 16.3 2.6 32.4 5.0 39.4 12.6 18.9 23.3 22.1 9.2 59.1 2.7 5.7 39.7 1.8 50.1 6.0 11.8 21.8 63.0 0.0 1.4 0.7 9.0 8.7 4.6 8.8 3.7 2.0 45.9 13.4 19.6 11.7 17.8 83.9 11.7 10.7 38.0 100.4 43.5 2.5 15.0 26.3 4.2 17.9 81.6 124.2 2.5 2.6 6.4 10.7 8.7 78.9 45.0 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.2;liver: 52.5;skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 120.1;Granulosa cells: 58.5;Hepatocytes: 53.4;Intestinal goblet cells: 32.0;Paneth cells: 67.0;Proximal enterocytes: 66.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 7.4;Daudi: 8.5;JURKAT: 13.5;U-937: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" NA NA 1200000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.8 0.5 3.1 3.2 2.7 0.9 2.3 2.5 2.9 1.3 1.3 38.2 30.0 0.7 0.2 4.2 2.9 0.9 0.7 3.8 2.0 12.2 52.5 0.7 0.3 3.3 2.7 0.6 4.1 1.0 1.9 0.6 3.5 0.5 31.3 0.6 12.0 0.3 24.7 1.2 23.7 1.2 1.4 0.4 7.7 1.1 2.2 0.2 0.4 1.5 0.2 0.1 0.8 2.2 0.4 3.1 0.3 7.4 0.2 0.2 1.2 0.2 0.2 0.3 0.5 0.5 3.8 8.5 2.4 0.0 0.2 0.6 1.1 0.5 0.1 1.5 5.5 4.3 1.3 2.6 0.0 0.9 0.7 0.3 0.9 0.8 0.1 0.2 0.0 13.5 2.8 1.7 0.3 1.1 1.4 1.4 1.5 2.6 0.4 1.3 0.7 1.3 0.1 0.4 0.4 0.8 0.2 5.8 0.2 0.6 5.0 6.5 0.3 0.4 2.4 0.7 0.2 0.9 3.6 1.3 0.3 7.2 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 3.1 2.7 2.5 2.9 3.8 2.0 3.3 2.7 3.5 1.4 2.2 2.2 0.1 3.2 6.7 0.7 0.4 0.5 0.0 1.3 1.2 0.2 9.1 5.7 1.4 2.8 0.9 0.0 0.0 0.0 0.0 120.1 0.0 0.2 0.5 3.2 0.3 0.2 19.7 0.0 1.8 0.9 0.0 0.2 11.7 4.4 1.3 58.5 0.4 53.4 0.3 0.0 2.9 32.0 0.0 3.2 0.9 5.4 0.0 0.9 0.0 0.0 0.0 0.4 0.0 1.5 0.1 1.0 67.0 1.2 0.1 0.1 66.0 9.9 4.8 0.2 0.0 0.6 0.2 2.3 2.9 1.1 0.3 0.0 0.4 0.1 44.3 0.2 CFDP1 "BCNT, CENP-29, CP27, p97, SWC5, Yeti" ENSG00000153774 "Craniofacial development protein 1" Q9UEE9 16 75293698-75433503 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 493.3;Paneth cells: 745.2;Proximal enterocytes: 612.2;Proximal tubular cells: 637.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041316, HPA048242" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA041316: AB_10794371, HPA048242: AB_2680327" "unprognostic (1.45e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-1)" "unprognostic (4.88e-1)" "unprognostic (3.97e-2)" "prognostic unfavorable (9.63e-5)" "unprognostic (5.81e-3)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.61e-2)" "unprognostic (1.42e-1)" "unprognostic (7.37e-2)" "unprognostic (2.85e-2)" "unprognostic (6.54e-2)" "unprognostic (1.36e-1)" "unprognostic (4.92e-3)" "unprognostic (1.25e-1)" 45.0 51.0 57.4 24.0 58.0 35.0 45.2 60.8 75.3 69.1 57.9 47.5 30.4 58.6 62.3 41.2 55.6 29.7 36.8 57.1 61.7 64.5 43.1 37.3 27.1 58.8 59.3 83.1 41.2 30.8 57.1 63.1 58.8 39.9 40.2 49.6 39.4 38.1 35.7 42.4 36.4 51.0 56.7 30.2 34.7 59.5 59.6 57.0 45.0 34.9 35.8 44.8 50.7 60.8 65.0 47.6 158.9 59.2 141.2 156.3 47.2 63.2 74.1 83.0 119.1 82.5 86.6 61.3 91.1 79.3 92.7 71.5 123.3 101.9 164.9 26.4 58.6 63.0 46.6 177.2 97.3 69.2 51.6 98.4 85.5 100.2 121.4 144.6 91.5 114.0 91.3 28.3 93.9 149.0 102.2 152.6 77.1 110.0 24.8 182.7 64.3 108.5 93.1 35.5 94.5 79.4 105.7 22.3 92.5 136.4 91.8 121.6 53.8 59.2 63.1 63.2 40.8 54.4 89.2 228.6 59.3 89.9 53.3 61.3 45.5 60.8 31.2 47.8 44.5 33.6 42.7 34.7 48.8 35.4 38.7 36.5 38.1 28.5 46.2 48.7 68.5 25.8 57.4 58.0 60.8 75.3 57.1 61.7 58.8 59.3 58.8 56.7 59.6 60.8 87.4 38.5 57.5 37.5 45.5 57.9 116.3 135.9 47.3 87.2 89.5 103.4 34.7 91.5 111.2 115.8 116.7 119.0 50.5 493.3 197.6 79.1 133.7 197.7 118.5 97.6 82.2 78.9 49.5 94.9 114.0 82.9 61.2 121.3 28.5 194.5 62.8 153.9 77.1 62.2 50.5 219.2 59.0 53.1 44.5 69.7 125.2 51.1 33.8 45.9 64.8 60.8 84.5 49.8 75.6 92.4 745.2 112.5 42.3 116.9 612.2 637.6 205.3 112.5 98.6 55.3 88.2 311.2 178.0 49.5 65.6 154.9 51.6 103.5 120.0 130.4 CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Distal enterocytes: 173.2;Paneth cells: 108.7;Proximal enterocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 91.4;CAPAN-2: 59.1;OE19: 58.6;RT4: 44.0" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" 5.8 1.1 1.9 6.0 3.3 0.4 9.0 8.5 3.3 4.9 6.5 37.2 52.7 1.4 1.5 8.6 13.2 13.6 0.6 2.0 3.7 12.2 32.1 27.3 0.4 5.5 3.0 2.0 24.2 32.1 3.7 1.6 5.6 10.1 25.1 3.7 21.1 7.0 0.2 17.9 56.4 1.5 1.7 0.4 30.4 6.6 3.4 0.7 4.9 0.1 2.3 8.3 6.2 6.7 28.9 3.2 2.7 4.6 0.0 0.0 35.4 0.1 0.1 0.8 0.9 91.4 59.1 1.3 9.4 0.0 4.9 27.0 8.6 5.0 0.6 17.3 6.0 2.4 1.3 1.8 0.0 0.4 3.6 0.0 1.0 1.3 0.7 0.0 0.3 7.8 1.2 8.1 0.0 26.8 5.0 0.6 22.9 58.6 2.5 5.4 2.8 4.3 17.9 44.0 8.9 4.4 1.8 27.1 1.0 10.3 33.5 0.3 0.5 0.3 8.3 0.5 1.2 7.7 8.4 5.2 0.3 3.3 2.4 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 1.9 3.3 8.5 3.3 2.0 3.7 5.5 3.0 5.6 1.7 3.4 6.7 0.1 118.6 33.3 2.3 0.2 0.3 3.3 5.9 0.6 4.3 14.9 9.1 0.7 24.3 22.4 3.7 0.0 3.5 0.5 173.2 0.0 21.5 0.3 13.8 2.1 0.6 10.3 2.7 0.8 25.4 0.3 2.3 54.6 27.3 0.0 0.5 0.0 29.6 0.3 0.0 10.4 32.7 8.2 0.0 0.4 1.2 0.6 0.5 3.6 0.0 2.1 13.5 0.0 3.5 11.7 49.5 108.7 0.7 0.5 11.9 88.7 3.0 46.8 1.5 0.0 0.1 1.0 1.5 6.9 4.2 1.8 0.4 0.6 1.8 27.2 18.3 CHMP1A "CHMP1, KIAA0047, PCOLN3, PRSM1, Vps46A" ENSG00000131165 "Charged multivesicular body protein 1A" Q9HD42 16 89640816-89657738 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transcription, Transcription regulation, Transport" Repressor Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA006776 Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Centrosome, Cytosol" "HPA006776: AB_1078520" "unprognostic (7.12e-2)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (1.41e-2)" "unprognostic (7.29e-2)" "unprognostic (8.03e-3)" "unprognostic (1.28e-3)" "unprognostic (3.92e-3)" "unprognostic (2.42e-1)" "unprognostic (3.53e-1)" "unprognostic (2.21e-1)" "unprognostic (2.56e-1)" "unprognostic (7.98e-3)" "unprognostic (1.59e-2)" "unprognostic (4.19e-2)" "unprognostic (3.24e-1)" "unprognostic (1.73e-1)" 30.3 31.2 46.3 21.1 44.5 31.4 29.4 41.2 53.4 34.3 36.9 42.7 37.8 35.8 17.0 65.4 31.6 24.8 33.1 46.8 42.7 36.6 30.6 28.7 27.5 45.3 44.3 25.0 25.7 30.4 24.8 24.7 44.0 33.5 23.0 5.4 31.8 22.1 50.0 48.7 42.5 22.4 44.3 31.6 34.0 37.3 45.7 30.5 28.3 25.9 24.3 35.6 36.9 44.2 70.5 66.3 29.5 46.2 42.2 38.2 75.3 53.0 54.3 79.3 38.7 97.1 111.5 37.7 53.2 70.1 52.9 88.3 52.6 69.7 36.7 34.2 82.7 31.0 23.4 108.5 57.8 23.0 31.7 54.7 75.6 74.6 33.8 42.7 41.2 46.2 69.9 18.2 45.6 141.4 55.1 88.3 58.1 78.6 63.5 60.1 58.3 39.8 60.4 43.0 52.7 70.8 103.5 34.3 38.1 27.5 117.6 48.5 63.1 52.7 61.6 65.3 45.8 52.1 59.1 51.1 88.1 54.9 62.5 66.7 51.6 108.9 54.4 62.7 42.0 36.3 43.6 50.1 44.2 33.4 27.5 33.4 86.0 49.8 82.3 49.4 58.5 64.1 46.3 44.5 41.2 53.4 46.8 42.7 45.3 44.3 44.0 44.3 45.7 44.2 31.1 32.1 23.6 17.3 27.5 23.8 24.5 28.8 13.1 24.6 33.9 27.6 16.8 28.6 26.6 31.3 8.4 57.7 43.2 147.3 37.2 55.3 56.4 27.2 26.3 28.3 44.3 16.2 8.8 59.5 74.4 26.9 36.2 35.0 27.9 33.0 23.2 31.1 47.6 43.7 7.9 57.7 30.5 30.4 23.8 125.5 20.5 28.3 23.2 11.2 62.8 36.3 43.3 11.1 9.5 84.7 121.6 24.0 14.8 31.7 109.6 40.9 22.4 20.5 26.3 17.1 27.1 45.4 33.3 26.3 32.5 66.2 28.6 28.8 58.2 36.5 CHMP2A "BC-2, CHMP2, VPS2, VPS2A" ENSG00000130724 "Charged multivesicular body protein 2A" O43633 19 58551566-58555105 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041153, HPA042031" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 230000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA041153: AB_10964358, HPA042031: AB_10961727" "unprognostic (1.80e-1)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (2.54e-1)" "unprognostic (3.86e-2)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.98e-1)" "unprognostic (2.21e-1)" "unprognostic (3.09e-2)" "unprognostic (4.23e-2)" "unprognostic (2.71e-2)" 131.8 185.9 144.9 86.8 149.6 162.3 125.1 153.7 171.9 108.9 143.5 141.3 113.4 111.7 150.1 154.9 104.6 83.1 182.6 144.4 147.8 163.3 161.3 116.9 81.9 151.1 147.0 101.9 125.0 147.8 118.7 95.8 151.3 112.5 124.1 75.2 137.2 97.1 222.9 158.4 121.9 83.6 149.0 121.2 143.8 73.9 146.8 82.6 123.2 151.7 95.1 114.3 113.7 157.4 110.4 290.9 91.4 85.0 138.9 172.9 112.9 100.0 204.3 52.0 56.0 86.3 160.1 29.3 143.2 168.1 149.2 87.7 76.1 190.4 43.7 98.8 628.2 71.8 214.0 134.7 266.6 121.1 108.0 201.5 266.0 81.5 257.8 175.3 153.1 135.5 86.8 135.6 159.5 187.1 153.7 111.3 38.3 304.2 220.3 65.2 78.6 222.0 230.1 246.8 107.3 181.2 162.0 213.7 123.4 57.3 164.3 121.5 174.4 262.0 37.7 77.2 117.3 339.0 404.9 95.2 185.0 141.0 176.6 278.9 247.4 351.1 134.9 232.7 114.5 127.0 148.0 153.1 216.2 123.0 102.0 116.3 820.6 131.6 243.9 197.1 215.5 208.4 144.9 149.6 153.7 171.9 144.4 147.8 151.1 147.0 151.3 149.0 146.8 157.4 166.1 99.3 119.8 9.4 72.9 165.6 261.4 287.7 69.4 73.9 124.7 120.6 118.7 154.4 207.2 165.5 16.7 288.8 76.5 555.2 442.2 332.6 121.9 194.0 109.2 143.6 155.4 142.5 5.3 522.5 296.8 113.5 115.7 198.8 121.5 102.1 142.5 214.0 269.1 52.2 5.6 296.6 217.7 142.0 145.8 90.9 145.1 134.5 215.3 6.5 203.6 217.6 147.2 3.0 13.4 479.8 615.3 133.2 77.3 258.5 607.0 599.8 242.1 94.3 85.5 103.9 169.7 116.8 89.7 109.5 198.5 460.0 89.2 149.3 226.3 372.7 CHMP2B "CHMP2.5, DKFZP564O123, VPS2B" ENSG00000083937 "Charged multivesicular body protein 2B" Q9UQN3 3 87227271-87255556 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 445.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035069, HPA052754" Uncertain Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA035069: AB_10602798, HPA052754: AB_2681936" "unprognostic (7.83e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (4.05e-2)" "unprognostic (1.51e-1)" "unprognostic (2.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "unprognostic (9.78e-2)" "unprognostic (8.69e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (5.76e-2)" "prognostic favorable (1.74e-6)" "unprognostic (6.52e-2)" "unprognostic (2.29e-1)" "unprognostic (6.41e-3)" "unprognostic (1.21e-1)" 26.0 24.2 15.7 22.8 20.2 42.7 26.3 22.3 22.2 28.9 16.2 41.6 38.5 29.5 22.5 35.2 22.6 28.8 27.0 15.1 18.2 29.6 34.5 22.9 21.9 25.1 21.0 24.9 29.2 24.3 30.4 25.0 24.1 34.9 37.5 15.3 24.9 27.7 35.3 26.4 40.8 29.6 23.7 22.1 31.1 16.1 20.3 17.2 43.1 28.0 21.6 42.3 29.7 31.2 68.4 71.6 25.4 17.4 45.0 38.4 29.7 52.8 71.2 45.1 57.1 57.0 115.0 25.3 36.7 60.1 38.6 35.0 31.6 37.6 56.0 41.7 34.7 29.5 24.6 25.4 39.2 44.9 42.5 29.3 63.2 42.9 58.3 42.6 35.8 29.6 17.3 36.7 50.2 53.2 41.1 18.3 32.4 91.1 65.5 21.4 31.0 26.1 36.0 71.3 9.7 10.8 54.2 45.6 91.4 28.8 40.6 13.7 30.6 42.9 36.5 445.0 37.7 37.7 56.3 41.6 47.6 24.8 30.9 124.7 50.7 136.7 27.3 65.2 37.3 49.6 34.6 34.8 55.1 53.4 32.0 32.4 96.8 31.4 67.8 31.3 52.4 37.8 15.7 20.2 22.3 22.2 15.1 18.2 25.1 21.0 24.1 23.7 20.3 31.2 56.2 83.3 68.7 11.4 58.7 132.0 254.5 90.0 53.5 19.9 59.8 52.1 68.8 62.9 85.0 49.7 4.2 75.4 45.7 268.7 138.9 170.6 6.8 86.7 45.2 54.4 46.7 36.2 14.1 261.2 187.0 68.9 48.4 86.9 74.1 27.1 48.5 60.8 86.9 37.0 15.1 80.3 73.2 61.9 87.6 7.5 66.2 72.6 40.9 9.4 62.0 213.9 42.2 10.6 36.0 237.4 241.3 96.3 30.0 226.0 101.7 145.8 90.5 16.3 72.3 58.5 57.5 78.7 76.7 62.8 145.6 180.9 52.9 38.1 81.3 330.3 CHMP4B "C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B" ENSG00000101421 "Charged multivesicular body protein 4B" Q9H444 20 33811348-33854366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041401, HPA051751" Enhanced NA NA 53000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041401: AB_10965028, HPA051751: AB_2681591" "unprognostic (2.56e-2)" "unprognostic (6.12e-2)" "unprognostic (1.07e-1)" "unprognostic (9.04e-3)" "unprognostic (9.85e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.49e-1)" "unprognostic (4.37e-2)" "unprognostic (1.24e-2)" "unprognostic (6.44e-3)" "unprognostic (1.31e-1)" "unprognostic (6.09e-2)" "unprognostic (2.31e-1)" "unprognostic (5.50e-2)" "unprognostic (1.20e-2)" "unprognostic (3.33e-2)" 105.8 112.3 93.3 75.8 95.3 213.7 102.2 93.9 112.3 112.9 82.5 155.1 103.0 107.8 58.6 159.0 84.4 80.6 147.1 98.4 98.9 122.9 67.7 101.5 70.7 97.7 94.5 94.9 82.1 74.8 74.6 74.7 95.6 90.4 98.7 53.3 118.1 82.4 231.3 120.9 119.9 76.3 93.7 83.0 117.3 60.2 97.5 82.8 88.4 132.6 71.2 132.0 106.9 99.4 206.4 131.3 72.3 69.3 118.8 95.2 114.5 120.4 159.1 126.1 117.5 279.1 171.2 98.1 183.3 122.3 192.0 160.8 83.2 182.3 99.2 51.0 89.3 174.1 90.4 189.3 137.5 86.1 88.1 137.2 99.4 116.3 106.6 125.2 141.9 113.1 84.2 139.0 97.8 130.2 189.8 246.5 63.4 226.3 179.8 97.7 147.2 120.7 142.7 234.0 56.4 68.6 225.0 192.2 165.8 85.1 149.0 123.9 129.9 216.8 85.0 108.7 117.9 132.4 101.3 117.0 176.5 91.6 65.8 0.0 1.8 0.8 0.7 1.7 0.9 1.6 1.1 0.8 1.0 1.1 0.8 0.7 2.3 0.5 1.4 4.0 1.4 0.5 93.3 95.3 93.9 112.3 98.4 98.9 97.7 94.5 95.6 93.7 97.5 99.4 66.0 60.9 54.6 17.9 71.5 298.0 224.4 133.8 113.3 22.5 149.1 64.3 95.9 112.9 148.1 110.3 18.8 197.7 77.9 565.8 144.8 360.9 17.8 81.8 76.1 126.0 127.4 81.6 18.7 497.0 151.2 130.1 112.7 130.6 28.5 22.3 71.7 69.8 215.3 18.5 13.8 212.7 154.6 119.3 383.6 18.8 93.8 140.2 220.5 15.0 289.8 73.6 46.4 10.6 17.4 540.2 536.6 120.7 139.0 426.2 482.1 180.0 101.6 20.9 92.1 79.7 120.5 24.5 29.2 291.0 341.3 440.3 62.9 35.7 227.4 413.2 CHMP6 "FLJ11749, VPS20" ENSG00000176108 "Charged multivesicular body protein 6" Q96FZ7 17 80991598-81009517 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023001, HPA024460" Approved NA NA 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023001: AB_1848689, HPA024460: AB_1848691" "unprognostic (6.05e-3)" "unprognostic (2.25e-2)" "unprognostic (7.21e-3)" "unprognostic (2.26e-1)" "unprognostic (3.54e-2)" "unprognostic (3.41e-1)" "unprognostic (5.96e-2)" "unprognostic (1.74e-1)" "unprognostic (9.29e-2)" "unprognostic (1.46e-1)" "prognostic favorable (9.99e-4)" "unprognostic (5.67e-2)" "unprognostic (3.74e-2)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.00e-2)" "unprognostic (2.40e-3)" 18.9 18.1 13.4 13.5 13.0 8.9 19.2 12.9 13.8 21.3 10.8 21.4 13.2 19.9 9.5 24.7 16.2 8.8 24.4 12.9 10.9 21.4 35.4 17.8 14.1 14.5 12.6 15.6 19.2 19.1 16.2 13.6 13.2 19.9 15.6 18.5 17.2 12.6 45.1 22.0 18.9 17.2 12.4 25.6 17.6 10.5 12.3 17.1 18.2 29.2 14.7 18.7 18.0 15.6 27.6 43.5 32.1 19.5 16.8 17.2 22.2 26.6 29.8 44.2 32.3 10.9 14.8 28.0 20.7 42.2 27.4 18.5 7.0 30.5 31.3 13.5 23.8 23.1 9.0 38.0 25.0 28.1 28.0 18.4 20.7 27.5 29.7 27.5 62.4 28.1 24.4 22.9 23.0 25.8 34.9 28.8 10.4 7.4 26.9 27.3 28.5 19.0 25.2 37.1 10.5 31.9 19.9 30.8 29.9 25.6 27.5 21.4 35.7 61.1 34.5 18.1 36.3 13.8 3.6 14.4 26.1 17.0 29.0 66.9 40.6 84.1 37.2 42.7 23.9 26.2 22.4 30.5 32.5 19.8 24.6 22.0 25.9 43.7 52.6 30.9 19.0 39.2 13.4 13.0 12.9 13.8 12.9 10.9 14.5 12.6 13.2 12.4 12.3 15.6 19.1 6.4 9.3 5.9 12.8 6.1 8.9 16.3 8.0 20.2 14.7 16.6 1.0 17.2 14.5 14.7 4.2 39.9 20.1 36.8 13.7 37.4 1.5 8.2 11.2 17.4 21.1 8.8 1.7 43.9 31.6 16.6 20.4 9.9 21.0 23.8 18.2 17.3 41.6 10.1 1.9 19.7 18.3 24.2 6.5 2.5 10.2 20.1 16.0 1.0 37.1 26.7 35.0 3.0 4.4 33.9 35.5 12.8 11.5 9.5 36.7 23.2 8.6 44.3 13.1 15.8 14.1 9.0 12.2 14.0 5.8 50.3 16.7 18.9 22.2 8.8 CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 434.4;Distal tubular cells: 389.4;Hepatocytes: 353.6;Proximal enterocytes: 425.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" 66.9 55.3 22.1 28.0 24.4 58.4 32.8 26.0 26.5 34.0 24.7 113.8 85.4 21.8 34.1 74.5 20.8 48.1 53.2 30.3 32.9 76.1 185.1 52.7 18.6 32.9 31.0 19.1 42.2 54.1 21.6 26.3 35.8 34.3 81.9 20.5 49.9 27.5 81.0 45.5 70.0 27.6 26.9 20.2 112.7 10.7 33.3 20.1 49.8 86.5 41.1 44.8 41.3 28.4 72.4 72.7 28.3 109.0 120.4 113.8 41.0 56.2 69.1 44.8 48.0 66.6 140.4 12.6 59.8 77.7 47.7 89.0 56.0 83.9 51.5 44.8 20.0 50.8 58.1 103.6 93.5 66.5 73.7 116.7 98.8 51.9 53.3 68.0 82.1 37.9 81.2 79.5 52.5 43.5 27.7 72.5 29.0 118.4 35.9 35.9 46.2 34.0 92.5 144.1 17.4 44.3 96.4 178.2 48.7 49.9 101.0 66.3 108.3 47.5 50.3 76.9 36.7 45.0 131.6 59.4 84.9 42.2 44.1 255.5 227.6 274.8 49.5 204.4 51.5 40.2 46.2 50.0 152.1 33.0 29.1 41.4 173.3 56.5 207.4 95.1 60.7 116.5 22.1 24.4 26.0 26.5 30.3 32.9 32.9 31.0 35.8 26.9 33.3 28.4 28.3 44.8 117.3 20.9 26.8 72.3 62.4 48.1 20.5 11.0 101.6 39.2 80.5 243.1 50.7 103.0 10.4 33.3 38.3 434.4 389.4 96.7 52.5 68.0 48.8 39.5 55.6 58.5 24.8 150.6 62.4 38.2 112.7 114.4 37.4 18.9 78.1 353.6 68.5 11.8 21.0 136.2 34.6 170.1 134.8 122.6 29.5 77.1 129.9 19.7 113.4 32.7 36.0 9.5 23.6 173.9 206.4 29.3 24.0 80.1 425.0 231.1 33.7 10.3 26.3 46.6 41.4 13.7 19.3 50.6 108.5 66.9 32.9 65.7 161.4 130.8 CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46385098-46386608 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 18.5;intestine: 6.8;lymphoid tissue: 15.9;testis: 5.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 6 "basal ganglia: 18.5;cerebral cortex: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 3.4;SCLC-21H: 10.0;U-2 OS: 2.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 16.8" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "CAB022444: , HPA072083: " "unprognostic (7.11e-2)" "unprognostic (3.79e-1)" "unprognostic (5.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.63e-3)" "unprognostic (1.38e-1)" "unprognostic (6.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (2.96e-3)" "unprognostic (4.08e-3)" "unprognostic (5.02e-2)" "unprognostic (3.83e-2)" "unprognostic (3.64e-1)" "unprognostic (1.71e-1)" "unprognostic (3.56e-1)" "unprognostic (5.08e-2)" 0.1 0.5 1.6 0.2 18.5 1.7 0.1 0.0 4.6 0.1 0.0 1.5 3.2 0.1 0.0 0.0 0.1 0.0 0.1 1.8 0.1 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.2 0.2 1.2 0.0 0.0 0.0 0.1 2.4 0.1 0.0 0.0 2.0 6.8 0.1 0.0 15.9 0.6 5.0 1.7 2.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.2 0.0 0.1 0.0 2.1 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 0.0 1.8 0.1 1.3 0.1 0.0 1.6 0.2 0.4 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.7 0.2 0.1 0.4 0.1 0.1 0.0 3.4 0.0 0.0 0.1 10.0 0.2 0.2 0.0 0.1 0.2 0.1 1.7 0.0 0.3 2.8 0.0 0.0 0.5 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 18.5 0.0 4.6 1.8 0.1 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CIPC KIAA1737 ENSG00000198894 "CLOCK interacting pacemaker" Q9C0C6 14 77098126-77117287 "Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 132.1" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000644 Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" Nucleoli "HPA000644: AB_1079206" "unprognostic (3.93e-2)" "unprognostic (6.71e-2)" "unprognostic (2.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (2.41e-1)" "unprognostic (6.67e-3)" "unprognostic (3.73e-2)" "unprognostic (1.74e-1)" "unprognostic (2.31e-2)" "unprognostic (3.20e-1)" "prognostic favorable (1.77e-10)" "unprognostic (2.28e-1)" "unprognostic (2.32e-1)" "unprognostic (1.13e-1)" "unprognostic (1.21e-1)" 13.2 9.6 41.3 8.4 53.0 4.2 15.8 48.0 41.1 16.8 24.7 26.8 10.3 14.6 13.5 22.1 30.4 9.0 39.8 46.5 44.1 14.2 15.4 11.1 8.4 47.5 48.2 9.1 9.7 29.5 13.5 9.0 43.9 25.5 19.9 41.2 20.5 24.8 132.1 15.4 11.4 16.5 42.3 9.1 11.4 11.7 53.3 10.3 20.4 82.4 10.1 17.2 15.5 49.6 9.4 12.6 25.4 16.8 10.1 8.0 15.4 6.0 9.4 10.9 9.8 10.3 19.4 23.3 5.9 9.7 9.6 14.3 23.7 9.4 14.3 12.3 6.4 14.9 9.8 9.5 9.7 8.4 10.7 9.4 17.9 10.6 6.5 14.1 12.7 19.2 14.0 8.8 8.1 21.4 20.2 10.2 10.6 21.3 10.9 20.2 11.3 14.0 11.0 16.1 35.9 13.4 11.0 17.4 14.9 10.7 27.2 8.6 14.9 7.0 15.1 10.0 7.6 8.4 7.1 11.1 13.2 7.1 14.8 4.3 4.5 1.6 2.6 5.1 4.1 7.9 3.6 2.7 5.4 7.1 3.8 2.8 5.5 5.5 3.8 2.0 4.1 3.6 41.3 53.0 48.0 41.1 46.5 44.1 47.5 48.2 43.9 42.3 53.3 49.6 8.5 16.0 18.4 33.6 4.7 9.1 8.2 5.3 12.5 29.3 18.3 12.6 49.9 8.6 12.6 11.0 58.4 7.4 5.5 43.5 9.8 4.2 11.0 39.8 9.2 7.0 17.4 6.5 16.4 5.6 5.0 5.6 9.2 20.3 1.3 5.8 7.1 29.5 15.2 11.8 20.2 14.8 30.5 16.0 6.6 15.8 4.1 7.2 8.8 9.4 5.8 22.8 2.1 21.1 58.7 5.1 12.4 14.3 4.2 8.3 18.1 6.0 30.5 36.4 13.1 7.9 9.3 19.9 9.1 10.4 9.8 13.5 3.1 7.1 13.7 7.1 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 694.7;intestine: 653.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 2767.4;Distal enterocytes: 4691.8;Distal tubular cells: 2281.3;Horizontal cells: 5042.4;Muller glia cells: 3639.8;Rod photoreceptor cells: 3789.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 290.8" "Lineage enriched" "Detected in many" 18 "monocytes: 290.8" "Cell line enhanced" "Detected in many" "CACO-2: 455.8;HEK 293: 1399.8;SCLC-21H: 792.2;SH-SY5Y: 352.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favorable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 90.7 60.0 471.6 25.8 627.0 3.2 47.2 641.1 694.7 105.2 192.7 653.4 36.0 222.6 16.0 54.5 197.9 17.9 269.8 428.7 482.3 161.0 9.0 60.3 4.0 427.5 440.4 58.8 27.7 108.2 74.0 4.7 345.1 301.8 151.9 471.3 37.9 208.3 80.0 76.5 120.8 113.8 434.5 6.8 479.9 97.6 596.2 2.8 87.9 47.1 5.1 298.4 101.6 383.6 2.4 54.5 321.1 14.7 4.4 2.3 6.3 37.5 0.3 2.4 1.4 455.8 7.3 0.4 36.9 29.1 9.9 70.2 109.9 1.5 0.2 9.6 1399.8 111.0 242.1 165.4 16.6 0.7 87.9 14.7 0.6 3.9 0.8 3.3 0.0 5.1 198.7 3.7 4.8 20.0 2.3 3.9 109.1 48.3 213.6 13.9 6.8 275.9 65.9 2.5 792.2 352.2 65.3 10.6 25.2 21.6 21.1 40.9 2.2 1.5 56.3 4.7 147.3 21.1 2.7 7.2 6.4 2.1 14.1 2.4 0.5 14.6 0.3 28.5 0.4 0.0 0.2 0.1 16.4 0.2 0.1 0.5 1.0 0.2 290.8 0.0 0.7 6.0 471.6 627.0 641.1 694.7 428.7 482.3 427.5 440.4 345.1 434.5 596.2 383.6 14.8 195.5 103.5 515.8 13.5 153.7 296.2 257.6 56.3 2767.4 41.5 48.9 553.5 145.8 117.9 114.0 1909.9 4.4 3.4 4691.8 2281.3 127.6 445.8 773.2 205.7 60.8 467.1 9.9 178.0 42.5 11.7 96.6 359.4 408.5 28.6 476.1 74.6 9.2 8.2 5042.4 147.0 726.0 187.2 2.8 44.9 147.4 304.1 39.8 181.5 88.1 74.2 3639.8 0.0 93.5 161.2 131.4 1996.9 1089.3 6.6 279.8 9.5 118.0 456.1 3789.9 59.2 15.4 222.6 127.3 97.4 22.1 175.2 41.6 19.1 12.2 755.6 220.1 CKMT1A CKMT1 ENSG00000223572 "Creatine kinase, mitochondrial 1A" P12532 15 43692886-43699222 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 83.9;intestine: 75.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 73.0;Distal enterocytes: 110.5;Intestinal goblet cells: 53.4;Paneth cells: 57.4;Proximal enterocytes: 94.5;Syncytiotrophoblasts: 94.0;Undifferentiated cells: 92.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 127.5;hTCEpi: 56.8;OE19: 144.3;SK-BR-3: 107.8;T-47d: 100.3" HPA043491 Uncertain "Intracellular and membrane" NA NA 2000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA043491: AB_2678510" "unprognostic (2.04e-2)" "unprognostic (2.53e-2)" "unprognostic (1.17e-1)" "unprognostic (4.02e-3)" "unprognostic (3.80e-1)" "unprognostic (7.44e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.51e-2)" "unprognostic (3.78e-9)" "unprognostic (3.52e-2)" "unprognostic (1.03e-1)" "unprognostic (7.37e-2)" "unprognostic (1.73e-3)" 1.8 3.8 20.8 7.1 22.1 0.0 7.7 29.3 46.4 10.1 12.6 75.0 70.6 0.5 0.4 83.9 2.1 9.4 0.8 21.9 27.3 6.0 0.2 0.9 0.1 24.9 15.8 0.1 3.5 12.3 8.5 9.5 26.9 4.4 69.4 31.8 31.4 1.1 0.1 38.0 63.1 3.4 10.7 0.1 23.3 0.3 23.0 0.2 2.8 0.0 14.7 8.3 26.1 25.7 0.3 2.9 0.7 0.1 1.3 0.0 31.9 0.0 0.0 0.0 0.0 6.8 22.1 0.1 1.4 0.0 2.4 127.5 22.4 39.0 0.0 0.0 17.1 0.0 2.1 0.7 0.0 0.0 6.1 0.2 56.8 0.0 10.3 0.0 0.0 5.0 5.7 0.1 0.0 34.8 0.0 0.2 10.1 144.3 8.2 0.1 0.0 6.7 6.7 4.7 47.1 20.0 0.0 107.8 8.6 2.9 100.3 0.8 0.0 0.0 2.3 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 22.1 29.3 46.4 21.9 27.3 24.9 15.8 26.9 10.7 23.0 25.7 0.1 0.0 0.0 2.3 0.3 17.7 10.5 30.3 1.8 6.7 4.2 5.2 0.5 10.0 14.9 1.8 20.9 73.0 0.1 110.5 27.4 4.2 0.0 0.7 0.0 0.3 18.0 0.0 10.6 20.2 23.5 0.4 26.0 0.8 8.9 1.5 0.0 0.0 4.5 6.7 9.0 53.4 12.2 0.0 0.7 0.2 0.0 0.0 5.4 1.0 0.0 4.8 0.0 1.5 1.6 12.9 57.4 0.0 0.0 2.7 94.5 1.0 4.1 11.6 0.0 0.0 0.9 0.0 0.1 16.1 18.5 94.0 0.4 0.0 92.7 20.1 CKMT1B "CKMT, CKMT1, UMTCK" ENSG00000237289 "Creatine kinase, mitochondrial 1B" P12532 15 43593054-43604901 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.5;esophagus: 74.3;intestine: 80.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 122.4;Distal enterocytes: 146.4;Intestinal goblet cells: 78.3;Paneth cells: 69.9;Proximal enterocytes: 124.6;Syncytiotrophoblasts: 137.9;Undifferentiated cells: 123.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 139.8;hTCEpi: 69.2;OE19: 156.0;SK-BR-3: 183.1;T-47d: 100.7" HPA043491 Uncertain "Intracellular and membrane" NA NA 2000000 "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA043491: AB_2678510" "unprognostic (3.47e-2)" "unprognostic (9.73e-3)" "unprognostic (3.10e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (5.19e-2)" "unprognostic (2.84e-1)" "unprognostic (3.64e-1)" "unprognostic (5.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (2.26e-8)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-2)" "unprognostic (4.36e-2)" 1.9 1.9 24.6 6.3 25.1 0.0 6.0 38.0 58.5 8.0 14.3 80.7 63.4 0.3 0.4 74.3 1.9 8.9 0.7 26.5 31.5 5.3 0.1 0.7 0.1 32.4 25.2 0.1 3.1 11.9 9.5 12.8 34.6 3.1 66.0 23.4 28.5 0.8 0.1 26.7 49.4 4.0 13.8 0.0 29.6 0.2 28.6 0.1 6.2 0.0 13.3 8.4 22.0 22.2 0.3 0.9 0.8 0.0 0.2 0.0 35.3 0.0 0.0 0.1 0.1 7.8 23.8 0.0 1.0 0.0 7.2 139.8 28.4 55.8 0.1 0.8 16.0 0.0 3.0 3.8 0.0 0.1 8.6 0.0 69.2 0.0 6.9 0.0 0.0 5.9 9.1 0.0 0.0 38.2 0.1 0.2 12.0 156.0 14.9 0.0 0.0 0.8 3.0 3.7 55.4 19.5 0.9 183.1 10.9 2.3 100.7 0.0 0.0 0.1 1.8 0.2 2.3 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 25.1 38.0 58.5 26.5 31.5 32.4 25.2 34.6 13.8 28.6 22.2 0.1 0.0 0.5 2.6 0.1 25.1 10.4 40.5 3.4 7.5 3.8 4.1 0.4 5.7 12.7 5.5 18.8 122.4 0.4 146.4 21.5 4.0 0.0 0.9 0.0 0.5 21.0 0.0 37.6 28.0 26.1 0.5 33.1 0.5 0.0 1.1 0.0 0.0 9.4 6.7 36.5 78.3 10.2 0.0 0.7 0.0 0.0 0.1 3.6 2.8 0.0 2.2 0.0 5.0 2.4 18.6 69.9 0.0 0.1 2.0 124.6 0.9 6.0 12.2 0.0 0.0 0.7 0.0 0.0 17.5 24.7 137.9 0.6 0.0 123.7 19.9 CLCA4 CaCC2 ENSG00000016602 "Chloride channel accessory 4" Q14CN2 1 86547078-86580754 "Predicted membrane proteins, Transporters" Transport "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 373.9;intestine: 257.8" "Group enriched" "Detected in many" 6 "Distal enterocytes: 597.0;Paneth cells: 183.2;Squamous epithelial cells: 158.7;Urothelial cells: 176.9" "Cancer enhanced" "Detected in many" "cervical cancer: 21.4;urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 1368 "RT4: 430.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA017045, HPA064770" Uncertain Approved "Nucleoplasm,Plasma membrane,Aggresome" "Intracellular and membrane" NA NA 150000 "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Aggresome" "HPA017045: AB_2291679, HPA064770: " "unprognostic (1.38e-4)" "unprognostic (1.52e-1)" "prognostic favorable (7.47e-4)" "unprognostic (2.73e-2)" "unprognostic (7.03e-2)" "prognostic favorable (8.63e-4)" "unprognostic (7.59e-2)" "unprognostic (3.35e-1)" "unprognostic (1.26e-1)" "unprognostic (6.01e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-2)" "unprognostic (2.29e-1)" "unprognostic (5.69e-2)" "unprognostic (3.43e-2)" 0.6 0.0 6.3 13.9 9.4 0.0 2.2 6.7 8.0 44.6 3.2 257.8 0.1 0.1 0.1 373.9 0.2 0.2 0.1 6.2 6.6 0.1 0.1 0.0 0.0 10.9 7.0 0.0 0.1 0.0 0.5 0.0 8.7 2.5 143.5 0.0 23.1 0.2 0.1 17.1 29.1 2.9 7.1 0.1 0.6 0.3 8.0 0.1 0.0 0.0 30.1 99.3 66.9 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 430.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.4 6.7 8.0 6.2 6.6 10.9 7.0 8.7 7.1 8.0 12.7 0.1 0.0 0.0 0.0 2.9 3.3 40.3 6.5 2.8 0.0 1.9 1.8 0.4 0.0 17.5 1.8 0.0 0.0 0.2 597.0 0.0 0.0 0.4 7.3 0.1 0.3 8.3 0.0 0.1 0.0 0.0 0.4 0.0 3.5 8.9 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 183.2 0.0 1.2 9.7 4.7 0.0 1.9 0.0 0.0 0.0 0.4 0.1 0.0 158.7 11.9 0.0 1.5 0.0 12.0 176.9 CLCN2 "ClC-2, CLC2, EJM6" ENSG00000114859 "Chloride voltage-gated channel 2" P51788 3 184346185-184361650 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.7;Proximal enterocytes: 27.4;Theca cells: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009397, HPA014545, HPA024108" Approved Approved Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB009397: AB_2079256, HPA014545: AB_1846881, HPA024108: AB_1846883" "unprognostic (1.13e-1)" "unprognostic (4.01e-2)" "unprognostic (6.48e-2)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (4.67e-8)" "unprognostic (1.72e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-1)" "unprognostic (2.50e-3)" "unprognostic (1.19e-1)" "unprognostic (4.40e-2)" "unprognostic (5.88e-2)" "unprognostic (4.60e-2)" "unprognostic (1.35e-1)" 1.4 5.1 2.2 1.8 3.1 1.0 1.6 3.1 3.0 3.0 1.6 16.2 9.2 3.6 3.8 1.7 2.4 7.5 1.2 2.0 2.4 3.0 1.7 1.2 0.7 3.4 3.0 4.0 4.5 3.4 2.8 1.0 2.7 2.3 10.8 0.6 2.8 2.9 0.9 1.6 8.4 1.6 2.9 1.5 2.2 10.6 3.3 1.3 2.7 0.5 0.9 2.1 2.0 4.3 8.9 3.2 2.5 6.9 2.2 1.8 5.8 2.9 1.7 3.1 2.0 16.8 3.0 3.0 8.2 1.6 8.0 15.1 3.6 3.5 0.9 2.8 4.2 2.7 7.0 7.7 1.3 1.2 2.6 3.6 2.7 2.6 3.0 1.5 2.9 3.3 1.0 1.6 1.1 5.9 0.8 1.6 3.7 7.6 4.4 5.4 2.3 10.7 3.8 6.9 4.0 2.4 3.3 11.4 5.2 1.6 9.4 1.2 1.4 1.5 4.5 7.7 7.7 3.6 5.5 2.1 2.7 5.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.1 3.1 3.0 2.0 2.4 3.4 3.0 2.7 2.9 3.3 4.3 2.2 3.2 4.1 16.6 0.4 1.0 0.9 0.8 1.2 2.1 2.5 2.8 1.2 14.3 1.1 0.0 0.0 1.0 1.9 81.7 0.0 3.7 2.3 2.5 4.5 1.9 3.0 0.8 4.1 2.0 0.6 2.6 2.6 4.4 1.3 11.3 2.5 0.6 0.7 1.7 8.1 3.7 0.0 1.0 0.3 2.7 5.3 1.1 0.0 1.9 0.6 1.7 0.0 6.0 15.1 2.2 16.0 4.9 0.8 0.6 27.4 2.3 2.6 2.5 0.0 0.9 2.1 3.3 1.7 1.1 0.4 1.5 1.2 62.5 9.0 0.5 CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 418.8;Paneth cells: 449.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.7;Daudi: 6.4;RT4: 6.7;SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" 6.2 1.1 0.3 2.3 0.4 0.1 5.7 0.2 0.3 2.4 2.3 16.4 4.1 1.0 1.9 3.3 1.4 1.2 0.7 0.3 0.3 4.5 10.4 4.7 0.3 0.5 0.4 1.6 4.0 2.1 0.9 1.5 0.4 1.3 6.8 0.1 6.8 1.3 0.5 13.5 10.1 0.3 0.4 1.8 15.6 0.5 0.5 0.1 4.9 0.3 0.3 5.0 2.7 0.6 0.1 2.6 0.0 0.1 0.7 0.1 7.7 1.9 1.5 2.0 3.1 1.5 4.2 6.4 0.0 0.1 0.7 2.5 0.0 0.0 0.2 1.3 0.0 0.0 0.7 0.1 3.5 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.3 0.0 0.2 1.9 0.3 1.3 0.0 0.0 0.0 0.9 6.7 0.3 0.9 2.6 6.8 0.1 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.9 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.5 0.6 13.0 9.6 3.1 0.3 1.1 0.1 6.6 4.2 2.2 0.1 6.8 3.4 0.7 30.0 6.9 1.8 0.0 19.1 2.8 418.8 7.9 26.9 0.0 6.0 2.5 3.4 7.7 0.0 0.0 10.7 14.9 3.3 59.7 6.7 4.5 0.8 8.2 10.6 16.8 0.0 0.0 49.9 26.4 2.4 1.4 0.0 0.3 4.6 3.6 1.9 1.4 1.1 0.0 0.0 0.0 28.1 449.9 0.4 0.1 3.3 99.1 4.7 10.3 1.1 6.6 1.5 3.2 0.0 0.0 3.9 0.6 9.4 1.3 0.3 55.2 12.2 CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1391.1;Pancreatic endocrine cells: 822.1;Paneth cells: 1276.4;Proximal enterocytes: 1390.9;Urothelial cells: 975.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 84.1;CACO-2: 90.2;CAPAN-2: 173.2;HaCaT: 364.9;MCF7: 129.8;OE19: 139.6;SK-BR-3: 150.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" 6.7 8.0 0.4 17.6 0.4 0.2 31.2 0.5 0.6 47.3 0.4 341.0 146.7 4.8 43.9 341.3 41.3 27.4 2.7 0.4 0.4 123.8 40.2 61.8 0.8 0.6 0.5 1.5 108.5 49.0 31.1 14.2 0.6 44.5 128.6 1.1 169.2 30.0 1.5 13.1 248.9 6.2 0.5 5.7 5.2 1.9 0.6 2.4 76.7 0.0 21.2 40.5 96.3 0.9 10.8 1.1 0.2 0.3 0.0 0.6 84.1 0.3 0.3 0.0 0.0 90.2 173.2 0.1 3.2 0.4 0.4 364.9 0.1 11.2 0.0 0.1 1.9 0.1 2.4 0.0 6.5 0.1 0.8 1.5 17.3 0.0 0.6 0.0 8.1 0.1 1.0 0.3 0.1 129.8 0.1 1.2 0.6 139.6 3.4 0.2 0.0 2.5 0.1 0.0 20.4 0.4 1.1 150.2 0.0 6.6 55.0 1.3 16.8 0.2 0.6 0.7 0.2 0.1 0.3 0.1 1.2 0.0 0.3 0.0 0.3 0.0 0.5 0.8 1.3 0.1 0.3 0.8 0.4 0.9 0.9 1.7 0.0 0.7 0.0 0.0 0.3 0.5 0.4 0.4 0.5 0.6 0.4 0.4 0.6 0.5 0.6 0.5 0.6 0.9 4.4 112.2 55.6 0.0 7.4 2.0 295.4 316.3 66.6 0.7 200.4 102.4 0.6 240.2 550.3 321.8 8.4 281.3 3.1 1391.1 39.2 787.5 0.1 210.1 26.6 9.0 326.8 4.0 0.0 790.0 342.7 5.2 15.3 225.5 5.7 0.1 3.6 41.2 33.7 0.0 0.0 741.7 362.2 4.1 6.4 0.2 1.2 11.0 24.9 1.9 11.0 1.6 0.0 0.0 0.0 822.1 1276.4 0.0 0.5 406.5 1390.9 78.6 498.5 6.7 0.0 0.2 38.6 0.4 3.5 366.1 2.6 588.9 10.2 1.0 691.9 975.8 CLDN8 ENSG00000156284 "Claudin 8" P56748 21 30214006-30216097 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 68.9;intestine: 50.8;kidney: 69.3;salivary gland: 40.1" "Group enriched" "Detected in some" 5 "Collecting duct cells: 224.3;Distal enterocytes: 110.2" "Cancer enhanced" "Detected in many" "prostate cancer: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HaCaT: 33.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA060605 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA060605: AB_2684331" "unprognostic (3.74e-2)" "unprognostic (3.12e-2)" "unprognostic (1.33e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (1.62e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 68.9 0.0 0.0 1.7 0.0 27.2 0.0 0.1 9.3 3.9 1.1 0.0 0.0 0.0 0.0 69.3 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.5 0.0 7.5 50.8 0.0 40.1 13.9 0.0 8.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 21.9 0.0 0.3 0.4 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 10.8 2.7 0.0 0.0 29.9 11.6 0.0 0.0 10.5 224.3 0.0 0.0 0.1 110.2 11.7 0.1 0.0 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.4 0.0 0.3 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 15.9 0.6 0.4 20.3 0.0 0.0 0.0 0.3 0.0 0.0 4.6 8.4 0.0 0.4 0.0 18.0 23.1 CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.7;skeletal muscle: 289.7;tongue: 98.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 509.6;Cardiomyocytes: 285.7;Distal enterocytes: 164.2;Late spermatids: 93.8;Proximal enterocytes: 126.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;EFO-21: 9.2;HDLM-2: 4.7;REH: 11.9;U-266/70: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" 18.9 1.5 3.2 4.3 4.4 0.2 6.5 1.5 2.9 19.0 0.5 28.6 20.9 2.1 0.9 2.9 4.5 3.0 102.7 2.1 5.0 54.7 0.3 70.8 1.7 2.1 3.8 0.5 1.1 1.7 3.0 16.5 2.2 2.6 25.8 16.9 2.7 1.4 289.7 1.2 36.6 2.3 1.8 44.5 1.6 1.4 5.5 1.0 7.3 98.3 1.9 2.0 2.6 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 13.5 0.0 9.2 0.0 0.0 0.3 0.0 0.1 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.4 1.6 0.0 11.9 0.3 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 12.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.1 0.1 2.0 1.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.5 3.2 4.4 1.5 2.9 2.1 5.0 2.1 3.8 2.2 1.8 5.5 1.9 59.6 509.6 30.0 4.6 1.4 0.1 0.1 0.0 1.2 0.3 0.5 0.4 285.7 5.7 26.9 14.7 0.0 0.2 0.7 164.2 0.0 1.7 52.9 4.6 0.5 29.8 13.1 0.4 8.6 0.2 0.1 7.9 0.5 5.7 1.3 0.0 0.7 0.0 0.0 0.0 5.4 23.5 0.0 0.0 0.0 93.8 0.9 0.7 0.0 34.7 0.6 53.8 0.0 0.5 2.9 2.9 51.1 0.7 3.4 3.2 126.0 2.9 11.4 1.8 0.0 6.1 4.3 1.0 0.1 0.1 0.1 2.2 5.8 0.1 13.5 4.3 CLSTN1 "CDHR12, CSTN1, KIAA0911" ENSG00000171603 "Calsyntenin 1" O94985 1 9728926-9823984 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 437.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012412, HPA077705" Enhanced NA NA 86000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012412: AB_1846981, HPA077705: " "unprognostic (4.63e-2)" "unprognostic (2.89e-1)" "unprognostic (9.76e-2)" "unprognostic (1.43e-1)" "unprognostic (9.79e-2)" "unprognostic (1.63e-1)" "unprognostic (2.44e-3)" "unprognostic (3.07e-2)" "unprognostic (2.54e-1)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "prognostic favorable (4.10e-7)" "unprognostic (1.12e-1)" "unprognostic (2.65e-1)" "unprognostic (4.05e-2)" "unprognostic (4.72e-2)" 28.1 27.4 49.7 23.1 65.8 10.8 31.7 29.5 137.5 61.2 80.6 59.5 29.2 85.4 21.4 51.4 69.8 48.1 35.9 79.6 15.5 41.3 6.1 29.6 33.5 24.7 18.4 60.2 65.7 36.2 48.4 35.7 32.8 61.8 38.2 110.8 79.0 45.7 23.1 83.5 41.1 49.4 7.0 28.3 31.0 15.0 23.5 35.0 40.0 28.9 27.1 38.0 59.9 45.9 120.9 55.4 52.5 64.8 71.1 50.1 35.0 80.5 71.4 82.0 70.2 32.1 235.0 90.5 203.1 95.2 52.6 157.7 41.2 245.6 32.1 114.2 74.6 27.3 53.0 39.6 116.1 46.3 41.4 58.0 156.5 105.9 50.0 78.6 113.9 52.7 13.1 52.6 35.8 47.2 53.2 26.6 37.9 53.1 59.7 80.6 21.4 42.9 73.1 20.9 91.4 53.7 94.8 160.1 79.1 22.1 34.7 73.9 155.0 89.3 80.5 56.6 109.9 75.6 75.4 124.3 72.2 79.6 95.7 6.2 0.6 2.3 3.0 0.8 1.5 0.8 1.9 2.3 1.4 1.0 1.3 1.2 0.2 0.4 0.9 0.8 1.6 1.5 49.7 65.8 29.5 137.5 79.6 15.5 24.7 18.4 32.8 7.0 23.5 45.9 40.2 28.9 15.7 63.6 23.7 43.8 61.0 73.7 84.2 205.1 53.3 47.0 14.7 55.8 44.6 51.5 437.9 34.1 35.0 221.1 1.9 29.2 4.5 44.6 47.0 36.0 30.7 17.9 150.9 38.8 14.3 40.6 29.6 52.2 11.4 54.0 35.3 2.2 28.8 180.0 138.1 96.5 14.2 24.2 13.3 5.6 46.3 21.3 32.0 46.9 21.0 160.9 28.8 90.0 56.0 59.7 66.9 50.4 31.2 42.4 54.9 27.9 68.3 165.6 85.5 39.5 31.4 24.6 37.5 44.5 26.1 19.2 33.8 47.2 59.6 42.7 CLUH "CLU1, KIAA0664" ENSG00000132361 "Clustered mitochondria homolog" O75153 17 2689386-2712663 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CACO-2: 266.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031505, HPA044346" Uncertain Supported "Nuclear bodies,Vesicles" NA NA 5500 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Nuclear bodies" "HPA031505: AB_2673912, HPA044346: AB_10962153" "unprognostic (3.48e-2)" "unprognostic (3.97e-2)" "unprognostic (9.02e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (2.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.84e-1)" "unprognostic (2.69e-2)" "unprognostic (5.64e-2)" "unprognostic (5.11e-2)" "prognostic favorable (1.92e-5)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-2)" "unprognostic (6.26e-2)" 30.8 56.7 13.8 18.1 12.7 14.3 28.5 16.3 18.3 19.8 19.7 45.9 46.6 21.3 1.9 67.7 19.2 15.4 80.8 14.5 11.2 50.6 135.0 19.6 14.6 14.6 13.2 17.0 50.4 15.6 20.3 9.0 15.3 24.7 13.2 7.2 32.1 11.8 127.8 47.5 34.2 8.5 9.3 25.2 35.1 25.2 17.3 6.4 25.2 52.9 11.1 29.6 29.2 11.2 69.5 131.9 8.9 33.3 20.2 14.1 99.9 34.9 13.0 41.9 31.0 266.2 30.0 122.6 41.5 19.4 26.9 127.6 45.3 52.9 14.7 43.6 86.4 68.0 112.2 93.9 17.1 53.7 44.1 22.6 29.7 48.9 24.7 9.4 20.5 43.3 81.8 42.2 11.7 79.8 69.6 58.0 28.2 35.8 67.8 104.7 37.0 70.8 26.0 117.3 43.9 32.6 40.0 129.4 44.4 6.6 72.7 31.3 33.7 33.7 44.9 92.2 80.5 18.2 22.9 49.7 35.4 73.2 41.6 0.0 2.2 0.0 1.7 3.1 1.3 2.2 1.0 0.9 2.4 2.2 2.3 2.1 0.2 0.6 2.0 2.7 1.5 0.9 13.8 12.7 16.3 18.3 14.5 11.2 14.6 13.2 15.3 9.3 17.3 11.2 5.8 6.4 20.9 20.9 6.5 30.5 12.0 11.7 16.5 18.5 23.5 22.7 42.1 41.5 16.7 18.4 22.9 9.7 7.6 47.8 11.7 18.4 1.8 12.7 10.8 8.5 25.8 22.1 9.9 18.3 8.2 6.8 22.4 24.6 1.3 18.1 6.8 122.1 13.1 8.4 11.4 38.8 14.2 10.3 6.3 4.0 5.0 7.9 21.4 4.7 7.4 6.5 2.1 7.5 6.2 19.6 21.2 6.0 11.7 22.9 39.2 35.1 14.1 17.1 6.6 12.3 11.3 8.6 17.5 42.4 35.5 8.2 7.2 43.3 68.3 22.5 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COMTD1 FLJ23841 ENSG00000165644 "Catechol-O-methyltransferase domain containing 1" Q86VU5 10 75233641-75236030 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 128.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 334.8;Exocrine glandular cells: 249.5;Paneth cells: 272.5;Proximal enterocytes: 435.9;Squamous epithelial cells: 285.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 30.2;PC-3: 38.3;RPMI-8226: 24.5;U-266/70: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042165 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA042165: AB_10794042" "unprognostic (2.53e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (9.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.23e-2)" "unprognostic (8.08e-3)" "unprognostic (9.35e-2)" "unprognostic (6.74e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (2.35e-1)" 11.0 17.9 1.1 1.0 1.5 1.5 9.8 1.2 1.8 18.3 5.8 23.3 7.4 7.5 0.4 70.6 7.2 0.4 33.5 1.3 1.7 29.1 37.5 11.7 0.6 1.7 2.0 8.0 128.6 3.4 17.1 0.9 1.7 11.8 1.0 1.1 23.9 1.0 28.2 25.3 25.2 0.5 1.1 12.4 27.8 3.4 1.6 0.5 18.5 0.7 0.7 8.3 29.0 0.9 6.9 2.2 0.5 1.3 0.1 0.7 19.0 2.1 1.0 0.3 0.6 1.6 6.0 20.0 3.5 0.4 1.1 9.0 0.9 1.9 0.1 3.2 30.2 0.8 4.8 3.3 1.1 3.5 3.3 0.6 3.2 0.1 2.9 1.3 0.3 3.6 7.8 4.7 0.1 6.2 5.3 11.0 1.2 5.1 38.3 10.6 1.3 24.5 1.8 0.6 8.4 2.3 2.4 16.0 4.8 0.5 8.9 0.5 1.4 0.6 5.9 1.2 2.1 21.5 4.5 9.8 0.7 3.4 0.6 0.0 7.1 3.9 10.6 10.0 11.6 7.1 10.6 11.0 8.5 5.6 3.5 6.1 1.4 7.3 9.4 15.3 8.9 6.8 1.1 1.5 1.2 1.8 1.3 1.7 1.7 2.0 1.7 1.1 1.6 0.9 23.6 19.2 11.5 1.6 18.2 29.4 40.5 54.1 133.1 6.0 29.3 37.1 31.1 57.2 33.8 53.3 10.4 33.4 30.8 334.8 144.8 162.8 1.6 10.5 7.7 13.5 40.2 16.0 3.4 249.5 79.1 13.4 148.8 33.4 12.7 10.3 25.4 84.0 35.1 1.7 3.9 206.0 42.7 24.2 21.3 3.5 9.6 21.8 37.4 6.5 31.8 10.7 24.7 1.5 0.5 109.2 272.5 7.2 50.8 38.7 435.9 140.3 11.3 34.5 32.9 6.2 25.6 2.6 3.4 285.3 38.2 30.4 29.2 10.7 143.8 56.7 COPE epsilon-COP ENSG00000105669 "COPI coat complex subunit epsilon" O14579 19 18899514-18919387 "Metabolic proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034345, HPA041605, HPA043576" Supported Enhanced "Golgi apparatus" NA NA 66000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB034345: AB_2081323, HPA041605: AB_2677578, HPA043576: AB_2678563" "unprognostic (1.48e-1)" "prognostic favorable (2.41e-4)" "unprognostic (1.15e-1)" "unprognostic (5.17e-3)" "unprognostic (1.04e-1)" "unprognostic (7.40e-2)" "unprognostic (3.39e-2)" "unprognostic (2.27e-1)" "unprognostic (1.36e-1)" "unprognostic (1.49e-3)" "unprognostic (1.97e-2)" "unprognostic (8.75e-2)" "unprognostic (1.63e-2)" "unprognostic (1.68e-1)" "unprognostic (2.26e-1)" "unprognostic (3.16e-2)" "unprognostic (6.75e-2)" 102.3 163.7 127.2 85.5 133.4 159.6 100.3 139.4 176.0 101.3 131.3 113.8 90.5 104.1 45.0 160.3 89.8 44.1 135.2 122.4 131.0 141.9 194.3 108.3 91.7 140.6 132.0 80.8 152.0 80.8 160.1 59.3 130.0 127.4 37.7 23.5 144.2 65.4 128.0 120.9 107.8 42.9 137.1 150.0 126.8 171.9 135.9 82.4 123.7 50.0 56.9 99.2 107.1 151.2 186.7 177.4 99.3 177.3 89.0 104.7 287.2 159.2 150.8 174.8 198.7 215.1 148.2 150.8 210.5 134.9 112.9 123.2 82.5 161.0 33.9 94.2 369.9 89.6 150.9 331.1 236.1 180.0 221.1 128.3 149.2 106.2 115.6 92.5 138.9 170.5 140.2 373.6 90.0 443.0 196.9 341.0 188.4 243.0 420.2 222.4 89.6 448.2 115.8 185.4 138.8 222.4 100.0 159.1 181.1 44.9 134.8 291.3 140.9 110.5 81.5 283.3 170.9 357.7 337.5 187.7 189.1 309.9 187.3 656.0 598.5 639.1 337.1 533.1 298.1 391.2 321.9 298.6 528.4 381.9 236.4 270.9 594.9 344.4 468.5 659.3 449.3 930.0 127.2 133.4 139.4 176.0 122.4 131.0 140.6 132.0 130.0 137.1 135.9 151.2 110.5 3.2 16.2 22.2 204.7 159.8 197.9 390.9 54.1 53.2 140.5 111.6 10.4 111.5 205.8 115.8 29.2 386.5 242.8 408.9 463.7 323.7 179.7 134.4 131.8 127.1 168.5 130.5 8.6 368.7 439.1 140.7 166.2 187.8 102.9 176.7 113.6 153.4 447.2 57.2 11.3 445.5 303.2 189.4 286.8 381.0 144.8 217.8 245.5 4.7 373.5 251.9 187.4 8.5 20.8 336.7 421.4 133.2 417.5 255.7 425.6 493.1 152.6 72.1 124.9 92.8 200.5 178.4 202.1 108.6 196.6 542.2 174.9 235.3 297.4 267.2 CORO1B coronin-2 ENSG00000172725 "Coronin 1B" Q9BR76 11 67435510-67443821 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 301.4;Paneth cells: 324.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 221.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017616, HPA040113, HPA070456" Enhanced Supported "Plasma membrane,Cytosol" NA NA 960000 "Cluster 51: Monocytes - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB017616: AB_2087018, HPA040113: AB_2676850, HPA070456: AB_2686268" "unprognostic (1.94e-1)" "unprognostic (2.40e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.65e-4)" "unprognostic (1.02e-1)" "unprognostic (8.23e-3)" "unprognostic (1.49e-3)" "unprognostic (7.22e-2)" "unprognostic (1.86e-1)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-2)" "unprognostic (8.58e-3)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (6.64e-3)" 54.4 56.4 20.2 29.7 23.8 20.3 53.4 23.4 27.0 55.7 21.1 70.2 62.9 72.8 14.6 80.2 54.2 44.1 26.1 19.4 22.7 48.2 47.2 53.7 41.9 28.0 23.6 42.7 52.5 24.6 35.1 31.2 25.1 71.0 34.5 6.6 73.2 39.6 13.0 42.4 62.3 36.7 24.2 66.0 77.1 13.9 25.1 21.1 55.8 9.9 18.4 58.3 53.5 26.3 80.9 81.4 37.5 76.0 94.1 81.3 56.6 58.5 118.0 94.2 70.8 134.1 116.0 6.4 111.3 80.8 95.8 67.9 41.9 74.9 16.8 19.4 40.7 54.9 47.3 57.9 148.1 2.3 120.8 110.6 66.3 80.1 37.2 59.7 120.7 49.4 42.7 9.2 54.2 238.4 14.4 11.2 47.7 198.2 73.4 11.2 41.0 14.9 62.6 104.3 40.7 50.8 52.4 139.6 181.6 26.0 178.5 63.0 92.2 63.4 47.4 87.4 35.2 1.6 3.3 14.6 103.4 8.2 66.4 57.3 102.8 8.0 10.9 212.9 8.3 20.0 37.6 14.6 79.0 11.0 21.2 11.4 47.8 11.9 221.8 60.8 55.2 57.8 20.2 23.8 23.4 27.0 19.4 22.7 28.0 23.6 25.1 24.2 25.1 26.3 58.7 3.2 2.2 4.6 53.4 27.9 60.1 90.8 40.9 13.0 53.8 39.0 1.6 50.1 66.4 47.8 8.4 87.8 39.2 301.4 60.7 111.4 8.9 43.6 32.9 52.0 99.0 19.8 1.8 105.0 229.8 35.8 111.1 64.8 28.0 46.7 47.8 22.4 251.8 15.2 2.4 188.6 81.4 138.6 66.4 5.0 39.4 96.3 71.2 10.3 195.3 30.0 41.2 4.5 6.8 136.9 324.9 34.6 64.3 55.6 263.5 84.0 41.2 14.6 52.6 22.1 55.1 8.1 6.6 47.6 31.0 150.5 100.3 54.8 128.0 74.5 CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.2;Proximal enterocytes: 93.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Cell line enhanced" "Detected in many" "BEWO: 66.6;OE19: 56.4;SK-BR-3: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041161, HPA041302" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA041161: AB_10795537, HPA041302: AB_10794195" "unprognostic (4.49e-3)" "unprognostic (3.44e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-1)" "unprognostic (3.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "unprognostic (5.73e-2)" "unprognostic (2.79e-1)" "unprognostic (1.52e-1)" "unprognostic (4.50e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" "unprognostic (6.40e-3)" 1.9 1.7 1.9 4.9 1.5 14.8 4.7 4.9 3.2 6.1 0.0 17.5 34.3 1.6 0.7 15.2 4.7 18.2 0.3 1.2 2.9 1.1 3.3 7.4 2.9 3.7 3.4 0.3 0.4 2.5 4.0 2.1 4.9 14.3 12.9 1.2 6.1 1.4 0.3 9.3 35.1 2.2 0.8 3.0 11.1 9.2 4.5 5.7 1.2 0.3 5.9 12.8 7.7 1.8 8.4 2.9 0.6 2.0 1.2 1.3 66.6 0.6 0.7 2.1 3.2 19.1 1.4 0.1 9.4 1.2 3.2 23.1 7.7 12.7 1.3 6.9 1.8 0.2 11.6 17.1 2.7 7.9 0.7 0.4 15.4 1.0 18.6 0.7 0.7 10.0 6.8 3.8 0.3 6.3 1.5 7.8 8.6 56.4 2.2 6.1 0.1 0.2 1.3 23.5 1.7 2.4 4.4 45.3 1.6 15.0 5.3 12.8 0.6 0.2 9.7 0.2 2.4 0.7 4.0 0.7 0.5 2.5 2.8 11.2 1.4 11.4 2.4 2.9 5.2 0.6 3.9 3.7 0.5 0.5 2.5 3.3 1.0 1.7 7.8 0.7 11.9 1.5 1.9 1.5 4.9 3.2 1.2 2.9 3.7 3.4 4.9 0.8 4.5 1.8 2.8 12.8 27.8 0.7 3.1 6.6 18.9 47.2 14.8 2.1 8.5 4.3 1.9 28.6 46.4 0.0 4.2 10.5 2.1 76.2 0.0 4.5 2.6 15.6 11.6 6.0 7.2 0.8 11.6 5.1 42.2 2.2 36.2 19.9 0.0 38.1 0.7 3.8 6.0 1.7 10.5 15.7 20.3 12.0 2.6 3.9 0.0 10.6 0.0 1.0 1.8 0.7 2.1 0.5 0.8 22.6 19.7 0.4 1.4 15.7 93.0 1.7 35.8 1.7 0.0 1.5 3.7 0.5 3.3 29.4 9.9 15.9 10.7 0.2 36.3 30.4 CPSF1 CPSF160 ENSG00000071894 "Cleavage and polyadenylation specific factor 1" Q10570 8 144393229-144409335 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065167, HPA068906" Enhanced Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA065167: AB_2685426, HPA068906: AB_2686055" "unprognostic (6.37e-2)" "unprognostic (7.72e-2)" "unprognostic (2.41e-2)" "unprognostic (1.21e-1)" "unprognostic (2.93e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (1.05e-1)" "unprognostic (2.00e-3)" "unprognostic (6.45e-2)" "unprognostic (7.54e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (6.54e-5)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (7.90e-2)" "unprognostic (9.66e-3)" 39.1 52.0 16.2 11.0 16.6 20.4 45.5 15.9 23.3 53.5 16.2 54.8 27.4 48.8 3.8 49.2 49.1 9.0 44.9 15.9 14.9 52.2 76.3 43.3 12.3 16.8 14.9 56.6 88.6 6.1 78.0 6.8 17.1 61.7 4.2 5.2 49.6 7.6 41.0 55.3 68.1 5.7 14.6 70.5 68.9 132.0 15.6 15.0 52.9 5.2 6.8 41.2 44.0 16.2 21.4 29.4 26.3 27.7 13.8 11.0 25.7 19.6 12.4 15.8 16.3 29.8 27.0 24.6 18.7 14.8 10.7 19.1 14.9 16.7 4.4 22.2 43.0 48.3 37.4 48.6 11.7 18.6 28.8 12.1 6.9 14.5 8.5 9.5 21.2 40.1 41.1 20.4 8.0 90.7 48.8 38.6 15.9 17.9 41.0 34.7 10.6 19.9 17.0 31.1 21.3 21.1 25.4 15.7 14.8 7.4 27.9 20.5 18.4 10.8 41.3 23.9 22.3 12.1 10.2 23.3 14.6 31.0 13.1 3.8 5.1 3.3 4.8 6.1 5.1 4.0 5.2 5.1 5.7 4.8 4.5 4.3 0.9 4.0 6.2 2.6 6.7 4.2 16.2 16.6 15.9 23.3 15.9 14.9 16.8 14.9 17.1 14.6 15.6 16.2 10.1 16.0 22.5 10.1 9.5 10.1 4.0 6.6 6.2 9.6 15.1 16.9 8.3 20.0 10.7 9.2 12.5 10.1 14.5 26.4 1.9 9.5 19.5 9.6 7.8 11.7 13.1 15.8 9.4 11.5 11.5 10.7 21.9 11.8 14.0 20.7 8.9 8.1 15.1 8.4 6.9 28.6 8.2 12.4 12.4 40.4 14.0 11.7 14.2 3.7 11.9 5.0 10.3 5.5 6.5 10.5 8.8 16.1 17.9 4.1 24.0 6.2 11.7 14.4 6.6 7.7 9.0 36.5 23.1 12.2 12.4 7.3 11.5 7.6 30.3 4.3 CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 110.0;Hepatocytes: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008835 Supported Supported Mitochondria NA NA 45000 "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA008835: AB_1078563" "prognostic unfavorable (3.84e-4)" "unprognostic (1.38e-3)" "unprognostic (3.04e-3)" "unprognostic (2.46e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (2.17e-1)" "unprognostic (4.99e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-1)" "prognostic favorable (2.67e-7)" "unprognostic (9.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-3)" 24.3 27.7 16.0 22.3 18.4 38.9 22.7 20.2 17.3 20.4 32.0 67.4 70.7 25.1 7.3 22.0 25.4 27.7 25.4 14.7 17.7 38.4 67.9 25.3 15.9 20.6 22.0 18.3 23.6 27.6 14.3 18.4 19.3 20.3 44.6 22.6 26.0 21.9 9.9 17.0 71.3 34.9 15.9 27.4 35.6 13.5 22.1 14.0 15.4 14.3 12.3 18.7 18.0 13.9 29.4 50.9 7.3 48.6 31.2 28.0 2.1 22.9 18.8 17.7 3.6 2.0 96.0 0.1 82.2 60.4 62.2 93.5 63.9 13.6 5.3 46.8 6.3 71.5 52.3 24.0 46.4 41.9 82.6 29.2 6.6 35.5 21.4 24.1 63.5 28.2 7.6 56.8 16.5 83.6 34.4 73.7 0.8 149.7 53.2 94.7 1.2 127.1 41.7 71.7 1.0 31.8 63.0 119.9 20.2 4.8 107.4 40.0 64.5 38.3 0.9 77.7 33.5 43.9 60.1 29.2 40.3 30.3 42.8 8.2 6.6 9.5 7.3 7.7 4.2 1.9 4.4 4.4 4.4 2.0 2.7 5.5 3.2 4.9 6.7 10.4 2.8 2.7 16.0 18.4 20.2 17.3 14.7 17.7 20.6 22.0 19.3 15.9 22.1 13.9 44.4 38.5 28.8 35.6 13.5 9.4 11.0 9.0 28.5 4.8 9.6 7.6 25.5 22.8 18.0 23.9 64.6 15.9 39.3 110.0 19.6 13.8 14.7 33.2 22.6 30.4 16.2 30.9 5.6 9.5 3.9 16.6 31.1 56.7 29.7 23.0 40.7 108.3 15.7 1.7 5.7 48.9 10.2 39.1 11.5 43.9 9.6 24.6 0.0 28.1 31.4 12.7 23.7 7.1 1.7 8.5 43.4 32.0 28.6 9.6 83.4 11.8 23.8 43.0 39.5 18.3 21.1 14.5 10.0 14.8 7.7 7.8 24.0 17.3 67.4 9.2 CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.9;Pancreatic endocrine cells: 149.9;Paneth cells: 177.3;Suprabasal keratinocytes: 139.5;Urothelial cells: 243.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 20 "B-cells: 3.1;T-cells: 9.2" "Cell line enhanced" "Detected in some" "A-431: 57.9;BEWO: 35.1;CACO-2: 38.1;HaCaT: 36.9;hTCEpi: 27.8;OE19: 33.1;SK-BR-3: 29.5;T-47d: 25.8" "Low region specificity" "Detected in many" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA013835: AB_1847214" "unprognostic (3.25e-1)" "unprognostic (4.41e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.24e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.42e-3)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "prognostic favorable (8.06e-5)" 0.8 0.4 0.3 4.0 0.7 0.3 5.1 1.2 0.5 9.3 6.1 26.9 36.9 2.2 4.6 54.5 8.2 8.2 0.3 0.3 0.2 34.1 32.5 19.0 0.9 0.4 0.2 0.4 44.0 20.7 15.9 3.5 0.5 9.1 10.5 0.4 24.8 8.9 0.1 41.9 30.6 0.5 0.1 0.8 31.1 0.4 0.2 0.8 16.2 0.0 5.4 6.4 17.6 0.5 57.9 7.0 0.0 0.2 0.0 0.1 35.1 0.0 0.0 0.0 0.0 38.1 23.8 0.3 22.1 0.0 0.3 36.9 0.4 12.5 0.0 0.0 0.4 0.1 0.2 21.5 0.0 0.1 0.1 0.0 27.8 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 15.1 0.2 0.4 1.3 33.1 0.0 0.0 0.0 0.7 16.5 24.0 0.0 0.1 0.2 29.5 0.1 1.7 25.8 0.2 0.0 0.1 0.4 0.2 0.1 0.7 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 1.3 3.1 4.6 2.2 0.0 1.0 9.2 3.6 0.3 0.0 0.0 0.0 3.4 1.9 0.3 0.7 1.2 0.5 0.3 0.2 0.4 0.2 0.5 0.1 0.2 0.5 0.2 35.3 38.0 0.0 2.2 72.1 64.6 81.3 21.1 0.0 43.6 19.9 0.3 71.4 64.0 31.3 0.0 28.1 0.9 160.9 46.9 113.0 0.0 43.8 4.0 1.8 16.8 3.2 0.1 101.5 9.8 2.0 34.7 58.3 1.3 0.1 0.4 31.8 2.5 0.0 0.0 60.2 63.1 1.0 6.2 0.0 0.0 1.3 7.2 0.0 2.7 0.9 0.0 0.0 0.1 149.9 177.3 0.0 3.1 94.4 86.8 44.5 36.3 0.5 0.0 0.0 4.2 1.1 0.4 45.0 139.5 56.2 3.2 0.2 52.0 243.6 CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846729 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "RH-30: 1208.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Mitochondria "HPA052607: AB_2681883" "unprognostic (7.09e-2)" "unprognostic (2.45e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (4.39e-1)" "unprognostic (5.57e-2)" "unprognostic (1.05e-3)" "unprognostic (2.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.15e-1)" "unprognostic (7.38e-3)" "unprognostic (5.50e-2)" "unprognostic (6.50e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" 90.9 82.5 66.8 65.4 80.0 45.7 81.8 79.7 69.3 84.0 61.0 108.9 54.3 96.4 51.4 67.0 89.9 64.7 72.4 64.6 63.0 66.2 58.8 113.9 66.1 90.7 80.6 107.3 119.4 68.2 40.3 94.3 76.5 70.1 83.2 30.1 109.1 82.8 122.3 88.9 77.0 94.8 71.4 75.5 89.9 32.3 74.3 104.8 68.1 102.8 77.5 85.2 71.8 83.4 83.1 35.4 165.6 105.8 145.6 248.8 55.0 87.4 165.1 85.2 75.4 45.6 131.5 101.3 98.1 187.5 33.2 64.8 70.0 85.3 88.8 34.2 29.7 140.3 54.4 37.0 135.4 64.3 78.3 239.7 88.9 77.3 65.1 181.9 135.0 60.6 74.5 172.9 43.4 38.2 69.1 38.3 84.3 52.5 44.4 91.0 1208.7 133.2 66.2 118.6 31.1 68.3 122.1 69.4 105.3 100.2 125.8 110.4 109.3 75.0 80.8 85.6 31.5 51.4 59.6 120.3 84.4 58.5 59.7 12.6 9.1 14.4 6.1 8.5 7.2 6.6 8.6 7.1 8.7 6.0 9.8 7.6 17.2 8.2 7.6 7.2 6.2 7.4 66.8 80.0 79.7 69.3 64.6 63.0 90.7 80.6 76.5 71.4 74.3 83.4 50.9 73.7 42.7 31.3 28.5 67.6 45.2 34.6 51.8 19.0 51.2 36.6 34.0 78.6 27.6 47.8 16.7 43.7 48.8 151.1 15.6 72.9 52.2 33.4 51.2 59.3 48.7 50.1 15.8 135.0 41.4 51.0 20.4 50.1 24.7 44.2 86.4 59.1 42.3 20.2 11.0 39.4 16.2 76.1 43.5 151.9 51.9 39.5 42.7 16.9 81.9 44.4 42.2 17.6 27.9 105.8 49.3 48.5 30.3 70.4 57.5 30.6 18.4 11.2 72.3 49.2 53.3 6.3 25.1 39.6 76.1 56.2 34.3 34.8 37.3 99.2 CU639417.1 ENSG00000274559 "Histone H2B type F-S-like" 21 5972924-5973383 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;Intestinal goblet cells: 1.4;Paneth cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.2;T-47d: 2.2;U-2 OS: 1.6;U-266/70: 1.2;U-266/84: 2.2" "HPA042205, HPA043013, HPA048671" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (3.37e-2)" "unprognostic (2.63e-1)" 0.5 0.3 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.6 0.0 0.4 0.1 0.5 0.5 0.6 0.3 1.3 0.4 0.0 0.1 0.7 0.9 0.5 0.7 0.0 0.0 0.3 0.5 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.1 0.4 0.4 0.0 0.0 0.6 0.4 0.5 0.0 0.0 0.4 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.4 0.2 0.4 0.0 0.0 0.4 0.4 0.0 0.2 0.6 0.0 0.5 0.3 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.1 0.0 1.1 0.3 0.0 0.4 0.1 0.0 0.4 0.1 0.0 2.2 0.0 0.0 0.0 1.6 0.1 0.2 1.2 2.2 0.2 0.3 0.4 0.4 0.6 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.6 0.1 0.3 0.3 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 CXXC1 "CFP1, CGBP, hCGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1" ENSG00000154832 "CXXC finger protein 1" Q9P0U4 18 50282343-50287839 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044511 Supported Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA044511: AB_10963081" "unprognostic (4.47e-2)" "unprognostic (1.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.18e-6)" "unprognostic (3.82e-1)" "unprognostic (3.24e-1)" "unprognostic (5.08e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.10e-2)" "unprognostic (1.00e-1)" "unprognostic (3.83e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (2.41e-2)" 18.1 26.7 24.4 22.8 25.4 45.9 19.3 29.8 30.5 28.0 25.9 23.6 27.3 23.3 10.3 23.6 24.9 17.5 19.9 24.6 24.6 25.5 24.5 19.2 34.3 24.6 24.5 30.0 38.7 20.3 21.0 16.0 25.2 24.4 15.9 13.6 32.4 21.4 20.2 29.5 23.5 14.9 22.8 29.6 25.7 22.8 25.0 30.7 23.2 13.1 21.1 25.6 23.7 26.3 24.6 31.9 33.4 46.9 28.9 16.2 46.9 34.3 28.4 38.5 32.1 21.6 19.6 60.2 17.6 22.0 18.5 44.6 51.6 37.0 21.7 51.9 33.0 57.9 42.3 39.5 19.6 126.4 68.7 19.5 32.9 38.0 51.0 26.0 25.0 58.8 29.9 63.8 27.3 37.7 71.6 67.7 47.8 16.9 22.4 74.5 26.9 56.5 26.8 13.9 48.4 47.2 18.0 17.8 21.6 21.2 22.9 56.9 29.2 45.1 28.4 18.4 29.6 119.1 87.7 52.5 28.4 58.6 35.5 24.7 18.8 34.0 24.0 22.0 25.0 26.9 21.6 23.6 21.9 27.5 23.1 18.9 8.1 22.6 18.8 15.5 26.4 20.6 24.4 25.4 29.8 30.5 24.6 24.6 24.6 24.5 25.2 22.8 25.0 26.3 18.1 19.2 27.4 21.9 27.8 26.8 13.1 21.7 21.1 15.3 20.2 17.4 7.3 18.6 23.8 18.4 14.6 34.5 23.7 31.4 13.7 19.4 13.8 20.9 13.8 18.3 35.3 14.9 10.2 21.8 39.2 16.6 33.1 17.6 8.2 20.5 16.8 15.3 22.0 8.4 8.7 25.0 26.4 20.2 17.2 9.8 19.9 21.0 8.8 7.5 21.3 19.3 43.3 9.5 9.4 21.8 26.1 19.5 41.5 13.3 26.5 14.9 21.4 13.5 6.6 19.5 16.9 49.4 22.1 24.5 30.1 37.1 27.7 18.3 26.5 12.0 D2HGDH "D2HGD, FLJ42195, MGC25181" ENSG00000180902 "D-2-hydroxyglutarate dehydrogenase" Q8N465 2 241734602-241768816 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5" "Group enriched" "Detected in many" 4 "B-cells: 2.5;T-cells: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056216, HPA060548" Uncertain Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA056216: AB_2683070, HPA060548: AB_2732650" "unprognostic (2.85e-1)" "unprognostic (3.35e-2)" "unprognostic (6.98e-3)" "unprognostic (7.88e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.11e-4)" "unprognostic (2.49e-3)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (7.82e-3)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (9.60e-2)" "unprognostic (3.05e-2)" 11.5 17.7 6.9 11.2 8.0 18.6 7.6 6.2 7.3 10.5 14.9 16.6 11.4 11.8 13.0 15.0 16.1 14.1 11.4 6.6 6.1 15.9 19.1 10.6 12.0 8.4 6.9 14.8 16.6 15.2 10.5 8.9 6.6 14.6 14.6 3.2 18.7 14.9 33.8 39.4 14.9 9.3 6.1 15.1 14.7 4.9 7.3 7.4 18.0 23.7 11.5 8.9 9.6 8.6 10.2 10.5 6.2 9.6 14.7 7.9 21.5 9.7 12.2 9.6 7.7 11.8 21.9 8.3 4.4 9.7 11.0 23.2 5.9 7.8 4.0 8.8 5.7 15.9 11.3 20.5 8.2 19.0 12.1 14.1 13.7 7.6 7.3 18.5 9.5 13.1 20.7 5.3 8.6 16.8 16.0 19.7 3.0 13.8 20.8 19.5 6.9 16.2 17.6 36.7 20.4 7.2 9.4 23.8 6.6 4.1 14.7 6.7 4.1 14.9 5.6 7.9 5.8 9.9 1.9 13.4 10.3 20.8 10.0 0.0 0.2 0.0 0.2 0.2 0.4 2.5 0.1 1.0 0.4 0.1 0.6 0.2 0.0 0.0 0.3 0.1 0.8 0.1 6.9 8.0 6.2 7.3 6.6 6.1 8.4 6.9 6.6 6.1 7.3 8.6 10.4 9.6 14.3 33.3 10.4 19.8 23.5 13.7 25.6 14.3 22.8 22.7 10.6 25.8 16.3 18.4 14.6 44.0 13.0 40.9 23.5 10.5 3.6 12.5 13.2 9.7 31.8 6.9 7.1 8.7 15.9 15.7 23.0 19.2 5.7 28.0 13.2 46.0 18.2 11.8 9.9 56.4 14.2 10.8 7.5 4.8 16.8 12.6 3.6 15.9 5.3 37.4 8.2 28.6 12.8 6.7 32.0 18.0 15.0 19.3 26.4 31.4 13.9 12.0 6.6 14.0 11.7 2.1 7.0 25.7 14.8 22.6 14.0 27.0 49.9 22.2 DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB009108: AB_2090601, HPA034635: AB_2674256, HPA071875: " "unprognostic (1.14e-1)" "unprognostic (7.19e-2)" "unprognostic (1.33e-3)" "unprognostic (4.08e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-1)" "unprognostic (4.61e-3)" "unprognostic (2.11e-2)" "unprognostic (2.79e-1)" "unprognostic (3.73e-3)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.34e-7)" "unprognostic (5.41e-2)" "unprognostic (3.11e-1)" "unprognostic (7.86e-3)" "unprognostic (1.12e-3)" 43.3 40.0 90.5 27.0 94.7 23.7 37.4 76.4 113.2 44.3 20.8 51.3 22.2 51.4 17.0 42.6 38.7 28.2 82.6 99.9 80.1 27.6 18.2 36.0 22.8 110.9 85.1 39.2 28.6 118.0 61.2 32.6 112.6 30.0 25.5 43.5 56.3 38.0 87.6 44.2 32.2 49.9 76.0 26.5 39.5 51.3 101.9 34.7 31.3 63.4 24.6 47.6 39.0 116.2 65.0 74.7 68.4 71.9 122.5 90.7 55.2 102.0 105.2 127.0 89.9 99.9 48.6 88.8 40.8 213.0 70.1 63.5 84.3 129.5 96.1 111.2 85.0 92.5 55.6 84.7 94.4 50.7 109.3 109.6 62.0 138.3 82.3 86.9 110.3 79.4 40.3 61.4 97.3 55.6 92.8 52.5 74.0 78.6 78.3 82.3 120.1 63.8 70.2 39.6 83.3 74.1 57.1 67.7 60.6 59.0 43.5 36.5 84.3 115.0 82.7 50.0 77.2 37.8 32.7 78.9 107.6 81.4 82.5 8.3 11.3 12.7 14.4 13.0 11.7 10.1 8.2 10.8 11.2 6.8 5.6 6.3 9.2 9.2 15.6 8.8 7.7 16.5 90.5 94.7 76.4 113.2 99.9 80.1 110.9 85.1 112.6 76.0 101.9 116.2 28.6 32.1 25.4 9.8 23.2 10.1 10.3 19.1 25.6 27.2 19.6 17.8 56.4 18.6 20.0 29.5 25.0 29.8 19.4 41.0 19.6 22.5 7.3 21.5 32.8 26.6 16.7 27.3 28.4 19.9 27.1 25.1 49.5 27.8 29.2 30.8 29.6 19.9 28.8 90.9 26.7 31.8 24.4 21.0 11.3 9.3 44.7 21.2 16.0 8.4 27.3 14.9 23.7 12.1 29.7 26.6 33.6 51.9 24.7 9.6 34.2 19.6 19.4 45.5 19.7 28.3 30.0 40.6 38.5 29.0 11.8 25.2 20.0 33.9 24.9 10.7 DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423615-30430030 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Supported Nucleoplasm,Cytosol NA Yes 61000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA002832: AB_1080615" "prognostic unfavorable (1.64e-5)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.43e-2)" "unprognostic (3.65e-2)" "prognostic favorable (9.71e-9)" "unprognostic (1.10e-3)" "unprognostic (8.78e-3)" "unprognostic (1.10e-2)" "unprognostic (2.53e-1)" 21.0 21.4 17.6 27.4 18.4 22.2 30.5 18.7 22.5 18.6 18.9 56.4 32.0 18.6 20.0 28.3 28.1 19.5 31.1 18.4 19.5 39.7 21.8 16.2 35.5 18.1 17.6 14.0 24.9 32.1 10.3 16.0 19.0 21.8 58.4 12.2 25.5 19.3 44.7 25.1 27.7 20.5 18.4 27.8 24.3 9.1 18.1 24.5 20.1 36.9 35.7 27.0 19.1 19.4 124.7 149.8 66.8 85.8 18.4 24.1 61.9 58.4 35.1 87.4 87.9 114.7 103.4 168.1 119.1 36.8 54.9 95.9 141.4 115.1 103.5 89.2 221.0 98.3 61.5 150.3 24.1 177.0 144.2 28.6 64.8 96.4 55.6 25.4 88.7 88.2 125.8 57.4 61.5 217.8 210.0 189.9 88.8 124.2 119.2 293.1 74.8 218.1 98.9 80.2 141.4 80.4 39.0 137.7 55.3 41.5 118.4 73.9 45.9 66.0 59.1 85.8 107.2 36.9 118.4 217.5 43.8 145.7 79.6 70.6 36.7 38.1 54.0 70.0 75.8 146.7 68.4 61.4 86.7 128.7 60.9 59.0 4.6 76.1 79.2 94.6 76.4 81.0 17.6 18.4 18.7 22.5 18.4 19.5 18.1 17.6 19.0 18.4 18.1 19.4 34.0 19.2 15.2 0.7 38.2 90.2 53.3 92.5 33.6 23.3 45.8 48.9 34.8 51.5 37.9 44.1 8.4 103.2 22.7 130.3 127.2 135.6 13.4 32.6 29.9 47.4 38.5 29.6 2.6 124.8 101.0 28.3 27.5 66.5 31.1 40.2 31.1 23.2 76.9 15.2 2.7 142.3 73.2 21.0 49.1 45.1 19.6 26.9 48.0 1.0 73.2 25.0 23.7 2.5 4.4 89.0 115.8 19.9 24.1 86.9 68.8 76.7 27.8 21.4 19.7 23.7 40.0 3.3 44.8 39.4 80.3 27.8 28.3 53.8 168.5 45.7 DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 386.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012389, HPA012509" Uncertain Supported Mitochondria NA NA 1500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA012389: , HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" 96.5 17.2 26.6 12.0 24.7 10.8 81.2 24.2 44.7 131.5 26.1 72.2 4.4 94.4 8.7 39.0 80.5 44.0 63.2 23.9 33.5 67.1 32.1 62.3 20.6 31.8 28.2 67.7 16.5 17.5 26.0 18.3 28.1 65.2 7.7 5.8 58.2 27.0 13.4 67.7 38.9 11.9 32.0 49.4 35.4 13.4 27.4 9.6 65.1 4.5 7.8 61.0 91.0 30.9 2.0 20.1 0.7 28.5 17.0 26.6 3.8 0.0 10.6 10.9 7.3 40.4 6.7 0.4 24.4 26.5 0.9 2.4 0.5 9.7 1.9 0.0 14.2 1.9 7.8 22.4 18.2 0.3 1.5 18.8 1.2 12.2 0.9 3.7 33.3 14.1 0.4 11.1 4.8 63.0 1.5 27.5 4.1 4.3 12.2 0.2 0.9 10.5 21.6 0.5 1.5 5.7 0.0 4.7 27.4 2.9 37.7 7.8 0.1 16.9 24.7 11.2 0.0 4.1 12.8 3.3 11.3 5.9 4.3 141.3 15.4 135.0 14.8 37.4 5.8 49.7 4.0 5.3 26.8 39.6 2.7 3.4 27.8 29.2 44.9 93.9 4.1 11.4 26.6 24.7 24.2 44.7 23.9 33.5 31.8 28.2 28.1 32.0 27.4 30.9 102.3 28.9 14.7 10.4 76.8 66.9 88.7 49.6 56.3 4.5 132.8 96.0 39.5 62.9 36.9 82.8 29.2 15.5 84.4 386.3 178.1 148.2 83.1 62.6 94.2 101.2 150.0 20.4 0.3 32.3 37.3 154.1 33.1 75.0 113.3 121.7 94.9 31.9 223.2 0.0 0.3 71.5 109.9 139.7 301.2 23.6 180.5 95.7 103.2 14.0 64.2 120.9 40.2 4.5 2.7 85.1 299.5 153.1 24.5 95.2 61.5 165.8 50.5 25.7 105.2 122.7 153.0 4.1 12.5 35.8 59.2 18.1 41.1 21.3 104.6 67.0 DDX60 FLJ20035 ENSG00000137628 "DExD/H-box helicase 60" Q8IY21 4 168216291-168318883 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 40.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 57.6;Gastric mucus-secreting cells: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 27.4;BJ hTERT+ SV40 Large T+ RasG12V: 26.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA046952 Approved Supported "Intermediate filaments,Cytosol" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 4: Stomach - Digestion" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Intermediate filaments" "HPA046952: AB_10963572" "unprognostic (4.05e-2)" "unprognostic (2.87e-1)" "unprognostic (7.22e-3)" "unprognostic (7.71e-2)" "unprognostic (2.30e-1)" "unprognostic (2.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.15e-2)" "unprognostic (3.06e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (3.35e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (2.48e-1)" "unprognostic (3.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.44e-1)" 8.2 6.0 2.3 9.8 2.6 5.6 7.2 2.0 2.4 9.6 2.6 17.4 13.3 7.7 4.8 3.5 7.1 9.7 5.9 1.9 2.4 6.7 9.4 11.4 9.8 4.8 2.3 11.0 4.0 6.4 4.0 11.5 2.9 6.0 15.7 3.3 21.3 5.8 2.4 6.5 12.3 6.1 5.1 17.4 40.8 3.4 3.2 15.4 6.3 3.5 6.8 6.8 5.6 3.1 8.3 1.1 4.2 1.4 2.9 10.4 5.3 2.3 14.9 27.4 26.1 0.0 20.2 0.0 1.4 3.1 12.6 6.6 0.5 4.1 8.7 6.1 0.3 12.9 7.3 0.0 9.9 3.8 3.3 7.2 1.7 6.7 1.2 7.1 10.1 4.8 0.0 2.0 3.4 0.3 6.2 2.5 0.4 0.4 2.1 5.1 1.5 0.0 5.3 4.6 0.8 0.7 5.4 1.3 18.8 0.3 1.0 5.1 8.9 2.1 1.5 0.9 2.0 1.6 0.3 0.0 6.6 6.1 6.1 1.6 1.2 1.2 4.2 2.5 4.8 1.4 3.2 4.1 1.1 1.4 3.3 3.7 0.6 3.7 3.0 0.0 3.0 1.8 2.3 2.6 2.0 2.4 1.9 2.4 4.8 2.3 2.9 5.1 3.2 3.1 32.4 35.3 6.5 14.0 12.2 4.2 4.8 6.2 5.7 0.8 3.9 3.2 8.6 11.5 11.5 12.9 0.0 7.6 13.4 57.6 5.9 8.2 3.3 11.8 10.5 22.8 3.0 8.4 0.7 6.8 10.4 11.6 90.2 10.2 27.3 16.2 14.3 4.0 6.2 0.0 1.3 22.4 2.0 4.1 2.8 2.2 8.1 13.5 3.6 25.3 9.3 7.4 17.5 27.6 1.3 12.0 14.9 9.4 3.1 4.1 11.0 4.2 15.3 2.9 6.6 10.0 9.0 1.1 1.0 2.2 2.7 2.9 17.2 18.4 6.0 3.7 DEDD2 FLAME-3 ENSG00000160570 "Death effector domain containing 2" Q8WXF8 19 42198598-42220140 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Paneth cells: 178.2;Syncytiotrophoblasts: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043419 Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA043419: AB_10960747" "unprognostic (1.59e-1)" "unprognostic (5.90e-2)" "unprognostic (3.54e-2)" "unprognostic (5.87e-2)" "unprognostic (5.57e-2)" "unprognostic (6.48e-2)" "unprognostic (1.03e-1)" "unprognostic (7.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (6.39e-2)" "unprognostic (2.46e-1)" "unprognostic (3.59e-2)" "unprognostic (1.24e-1)" "unprognostic (5.80e-2)" "unprognostic (3.70e-2)" "prognostic favorable (3.26e-6)" 7.0 11.4 16.1 6.6 16.5 12.8 5.8 17.3 23.1 9.4 17.4 8.8 6.7 7.3 3.1 12.3 10.1 2.1 8.6 16.3 24.0 10.7 12.9 13.8 5.3 17.3 18.2 11.3 9.5 4.2 19.3 3.6 21.2 10.6 2.1 3.4 10.0 3.3 9.8 13.0 9.9 1.3 15.3 17.8 9.5 11.7 19.9 7.0 9.9 3.4 4.1 8.8 11.0 23.4 17.1 32.4 2.3 2.8 5.7 1.3 10.5 6.5 5.6 5.2 3.3 9.3 12.2 10.5 12.8 1.9 6.1 7.0 11.1 2.4 2.3 9.0 28.5 5.2 8.7 15.9 6.9 5.8 10.6 0.8 6.3 3.8 5.2 9.5 2.9 4.5 26.7 12.3 1.5 7.2 6.5 21.1 6.0 15.8 22.3 6.8 4.4 9.8 4.1 5.6 19.0 7.1 6.0 18.1 3.6 3.4 3.1 7.2 5.7 3.9 12.6 1.6 12.3 21.4 10.3 3.3 5.8 9.3 4.0 81.7 56.4 94.7 47.9 73.1 51.7 40.6 44.2 46.7 34.6 39.0 39.9 41.2 126.2 40.9 83.1 48.6 46.4 71.9 16.1 16.5 17.3 23.1 16.3 24.0 17.3 18.2 21.2 15.3 19.9 23.4 13.4 6.4 7.5 2.9 47.6 46.4 67.0 30.2 18.2 26.0 33.5 24.5 7.6 21.5 14.4 14.7 12.5 29.1 57.6 101.8 11.7 26.0 32.4 38.4 8.6 19.1 92.2 53.2 5.6 24.2 47.8 15.5 20.4 36.0 70.6 10.0 9.3 8.2 36.6 15.2 5.5 67.0 20.3 31.7 73.6 5.9 13.4 47.4 39.2 2.8 44.5 20.9 75.2 2.5 5.5 45.9 178.2 12.8 34.1 60.7 52.9 20.7 21.4 22.9 6.6 10.3 19.9 18.1 21.1 21.9 53.6 162.0 70.8 17.7 48.7 90.2 DEFA6 "DEF6, HD-6" ENSG00000164822 "Defensin alpha 6" Q01524 8 6924697-6926076 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 863 "intestine: 4819.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 448.9;Undifferentiated cells: 904.1" "Group enriched" "Detected in many" 5 "cervical cancer: 21.2;colorectal cancer: 75.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 14.7;NB-4: 15.9;RPMI-8226: 19.7;SH-SY5Y: 12.2;U-2197: 5.7" HPA019462 Enhanced "Secreted to digestive system" NA NA 260000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019462: AB_1847595" "unprognostic (7.48e-3)" "unprognostic (1.63e-1)" "unprognostic (1.34e-1)" 0.1 0.2 0.0 5.5 0.0 0.3 0.2 0.0 0.0 0.0 0.0 25.7 2862.9 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.2 3.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.1 0.3 3.3 0.0 0.3 0.0 0.2 0.6 4819.9 0.0 0.0 0.2 0.4 0.6 0.0 2.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 1.1 12.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.4 0.0 0.0 0.0 448.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 904.1 0.0 DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 114.9;Horizontal cells: 89.2;Oligodendrocyte precursor cells: 72.4;Paneth cells: 69.5" "Cancer enriched" "Detected in all" 6 "glioma: 28.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 57.7;BJ hTERT+: 60.8;PC-3: 29.1;RPTEC TERT1: 72.7;U-2197: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "prognostic favorable (9.35e-4)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (3.05e-6)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (3.54e-2)" "unprognostic (2.38e-3)" 15.4 3.9 28.9 2.5 32.5 0.6 11.0 23.5 25.8 25.0 46.9 12.0 3.9 26.2 5.1 9.6 30.7 11.1 16.1 25.2 28.8 14.5 3.1 17.6 2.3 43.7 39.7 21.7 2.2 5.0 26.3 15.5 33.7 11.4 5.6 11.5 2.6 5.4 7.1 3.9 8.9 16.0 34.6 12.2 6.6 2.1 32.1 0.8 3.7 7.8 1.8 12.1 11.4 26.2 0.2 0.9 57.7 0.5 6.2 1.1 12.4 2.2 60.8 9.5 15.3 0.0 0.1 0.1 0.4 0.6 10.2 0.2 11.0 0.8 17.8 0.0 1.0 0.0 0.2 0.0 1.6 0.2 0.1 2.8 0.6 13.9 2.1 24.9 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 12.3 0.1 29.1 2.1 3.7 0.2 72.7 0.1 4.6 14.5 0.0 0.0 0.0 16.7 0.1 0.6 0.0 10.9 2.2 32.1 5.9 0.3 0.0 0.1 0.9 0.1 3.9 1.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 1.2 0.3 0.1 0.2 0.1 0.0 28.9 32.5 23.5 25.8 25.2 28.8 43.7 39.7 33.7 34.6 32.1 26.2 13.8 0.0 3.0 34.9 0.5 1.3 1.9 0.1 0.6 7.4 1.9 1.0 4.3 0.0 1.3 0.0 8.4 1.0 0.3 114.9 7.9 0.0 1.4 0.4 8.3 4.6 9.6 0.0 10.0 0.0 4.9 14.8 1.1 0.3 11.4 22.4 9.7 0.7 2.4 89.2 23.2 37.1 0.0 0.3 2.1 1.0 18.6 0.6 1.8 32.8 0.1 16.2 0.0 72.4 42.3 0.1 69.5 10.5 0.0 2.2 3.8 0.1 1.0 10.5 13.1 11.8 11.3 0.1 0.9 0.2 0.4 0.4 1.1 0.2 42.7 1.2 DGCR2 "DGS-C, IDD, KIAA0163, LAN, SEZ-12" ENSG00000070413 "DiGeorge syndrome critical region gene 2" P98153 22 19036282-19122454 "Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000873 Uncertain NA NA 84000 "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000873: AB_1847632" "unprognostic (1.68e-1)" "unprognostic (4.27e-2)" "unprognostic (4.03e-2)" "unprognostic (1.33e-2)" "unprognostic (6.28e-2)" "unprognostic (8.51e-2)" "unprognostic (1.05e-1)" "unprognostic (6.86e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (2.06e-2)" "prognostic favorable (8.72e-7)" "unprognostic (3.63e-2)" "unprognostic (2.29e-1)" "unprognostic (6.27e-2)" "unprognostic (6.28e-3)" 25.3 28.6 45.7 14.9 40.4 7.4 26.4 34.6 48.9 30.0 24.7 34.0 26.2 32.9 12.9 46.5 27.7 19.0 33.6 44.1 42.8 31.1 30.6 28.6 16.8 45.2 43.3 35.9 44.6 26.3 33.1 16.4 43.6 34.7 16.0 9.1 33.7 23.5 27.2 61.3 28.8 15.6 38.3 25.5 30.2 25.3 52.0 16.7 39.8 19.5 12.5 31.2 32.1 38.6 43.2 26.5 32.6 58.3 57.9 23.2 31.8 28.3 34.8 27.2 26.8 45.7 47.9 22.7 38.7 30.7 19.4 79.7 24.2 27.2 11.4 19.4 44.4 15.3 16.0 37.0 35.1 28.8 33.4 33.3 61.6 21.1 24.3 23.4 30.3 14.2 115.6 19.3 14.0 45.0 15.2 31.0 27.3 67.8 19.1 26.5 34.4 8.9 46.2 46.8 44.4 32.8 52.1 36.0 32.6 17.6 33.5 25.9 27.0 50.0 25.6 26.3 23.1 21.5 8.5 14.9 23.7 16.5 38.9 9.5 10.3 16.5 6.1 5.3 5.3 4.3 6.5 6.1 6.8 4.7 7.8 6.4 23.5 4.6 3.9 4.0 9.5 11.3 45.7 40.4 34.6 48.9 44.1 42.8 45.2 43.3 43.6 38.3 52.0 38.6 16.4 19.2 27.0 34.3 10.0 9.7 10.8 17.1 17.6 30.1 23.4 20.6 18.0 30.0 23.3 27.6 14.6 17.2 9.5 59.7 0.0 24.9 13.7 9.6 11.2 13.7 19.9 4.2 35.7 21.9 19.0 13.5 27.0 16.9 8.2 24.5 21.4 27.3 12.1 37.0 43.7 30.3 18.3 18.5 4.7 22.2 17.1 10.4 8.8 22.5 16.4 18.5 11.3 54.8 32.6 30.9 24.0 22.6 11.1 18.8 27.7 10.6 14.0 23.0 13.1 14.4 15.1 12.6 12.9 22.1 12.4 10.8 11.8 17.7 28.4 16.8 DGKQ "DAGK, DAGK4, DAGK7" ENSG00000145214 "Diacylglycerol kinase theta" P52824 4 958887-986895 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 33.5;Intestinal goblet cells: 21.6;Paneth cells: 33.1;Proximal enterocytes: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026797, CAB033835" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB033835: AB_2091307, HPA026797: AB_10600902" "unprognostic (7.39e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "unprognostic (5.08e-2)" "unprognostic (3.37e-1)" "unprognostic (6.39e-2)" "unprognostic (2.90e-2)" "unprognostic (1.06e-1)" "unprognostic (6.45e-2)" "unprognostic (1.06e-2)" "unprognostic (9.77e-2)" "unprognostic (3.08e-3)" "unprognostic (4.38e-2)" "unprognostic (2.65e-2)" "unprognostic (1.65e-3)" 6.5 8.2 11.7 9.2 11.4 9.8 6.7 15.4 15.8 9.0 3.6 20.0 22.2 7.9 2.6 10.8 7.6 5.1 6.0 14.0 10.9 8.3 8.1 9.5 11.0 14.3 8.6 6.5 9.9 3.7 10.5 3.2 10.1 9.3 6.5 1.0 9.4 4.0 3.6 13.2 23.6 2.7 6.1 15.4 8.4 9.0 11.8 7.5 8.7 1.3 4.4 8.4 9.7 7.0 5.7 9.1 3.9 13.2 4.7 3.8 14.5 10.7 6.0 6.0 5.9 6.5 11.1 7.6 8.8 6.8 12.2 6.5 2.2 7.5 1.4 6.0 6.9 11.8 10.3 11.6 8.0 5.1 15.2 7.2 12.5 4.9 2.3 5.1 7.3 15.6 9.1 0.9 4.7 8.6 10.7 29.6 6.9 15.9 15.3 17.0 1.1 0.9 6.5 7.9 2.4 6.6 3.7 4.1 11.3 3.0 9.9 12.3 10.8 10.3 4.8 11.7 7.2 20.2 9.4 6.0 8.9 10.9 9.5 2.9 0.5 1.3 2.0 0.5 0.9 0.5 0.7 1.7 0.4 0.4 0.7 1.3 0.3 2.4 0.4 0.8 0.5 0.8 11.7 11.4 15.4 15.8 14.0 10.9 14.3 8.6 10.1 6.1 11.8 7.0 4.3 3.2 3.1 8.5 3.6 2.8 1.3 2.9 1.2 3.6 3.5 3.9 3.0 4.3 2.9 3.7 4.2 0.5 15.1 33.5 0.0 3.0 0.6 2.6 3.3 3.3 7.7 5.7 12.4 4.9 2.1 2.9 3.1 4.1 0.0 6.2 2.5 5.8 2.5 3.3 11.8 21.6 0.0 4.1 2.3 1.3 4.1 4.6 3.6 5.6 4.5 3.0 10.3 3.0 3.2 5.7 33.1 2.6 4.6 3.1 29.1 0.9 4.4 1.0 0.0 2.6 2.8 3.2 4.3 2.9 3.8 0.7 6.7 3.6 14.5 3.8 DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.9;intestine: 70.4" "Cell type enhanced" "Detected in many" "Club cells: 229.3;Distal enterocytes: 261.2;Early spermatids: 153.2;Paneth cells: 299.9;Respiratory ciliated cells: 155.9;Syncytiotrophoblasts: 267.5;Urothelial cells: 249.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 258.3;eosinophil: 99.2;neutrophil: 77.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 258.3" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 22.8;HUVEC TERT2: 21.5;NB-4: 33.7;THP-1: 98.0;TIME: 49.9;U-2197: 31.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036491, HPA036667" Approved "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" 10.0 0.2 2.2 12.5 2.4 8.5 5.1 3.0 2.6 8.6 1.6 70.4 1.9 1.2 0.9 28.2 1.0 5.7 53.9 2.5 2.3 0.3 3.1 7.1 20.2 4.2 3.2 0.7 0.4 0.2 0.4 2.8 4.3 0.8 46.2 1.2 6.1 0.5 0.3 3.3 5.7 4.2 3.8 7.6 10.8 11.3 3.2 2.2 0.3 0.8 26.8 17.5 10.1 4.5 0.0 0.7 0.0 0.0 2.5 10.2 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 6.5 1.7 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.9 1.0 0.4 0.5 1.3 6.1 22.8 21.5 0.0 1.0 0.0 0.0 0.0 0.1 33.7 0.0 0.3 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 98.0 49.9 0.1 0.2 31.4 0.2 0.1 0.0 0.0 0.8 18.9 0.0 258.3 21.0 99.2 0.0 25.0 0.6 6.5 0.0 0.0 21.6 5.0 0.1 0.0 77.3 0.4 5.1 1.6 0.0 5.9 2.2 2.4 3.0 2.6 2.5 2.3 4.2 3.2 4.3 3.8 3.2 4.5 0.3 0.0 1.3 0.0 1.4 1.7 19.3 72.4 0.0 0.0 0.1 0.4 24.4 0.0 229.3 0.0 0.0 2.5 0.0 261.2 0.0 4.6 153.2 0.5 0.0 0.6 1.8 0.8 0.2 25.3 1.3 1.5 7.7 0.1 91.0 0.0 0.0 0.6 25.0 0.0 0.2 51.6 36.7 10.2 38.8 45.5 1.2 16.6 0.0 19.7 3.5 3.9 0.0 0.0 0.2 68.6 299.9 0.4 6.4 6.5 1.5 0.1 155.9 0.1 6.6 0.2 10.9 1.1 0.6 0.3 1.4 267.5 3.8 0.0 8.2 249.2 DLG3 "KIAA1232, MRX90, NE-Dlg, NEDLG, PPP1R82, SAP-102, SAP102" ENSG00000082458 "Discs large MAGUK scaffold protein 3" Q92796 X 70444835-70505490 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001733, HPA078130" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA001733: AB_1078675, HPA078130: AB_2686879" "prognostic unfavorable (1.69e-4)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (2.77e-1)" "unprognostic (4.65e-2)" "unprognostic (3.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.20e-2)" "unprognostic (7.79e-2)" "unprognostic (7.92e-2)" "unprognostic (1.26e-1)" "unprognostic (5.98e-2)" "prognostic favorable (1.72e-10)" "unprognostic (3.36e-2)" "unprognostic (5.45e-2)" "unprognostic (1.51e-2)" "unprognostic (1.97e-3)" 3.6 3.7 14.6 4.9 16.0 0.6 11.7 8.3 19.2 10.9 9.5 18.6 13.4 8.3 25.5 20.4 19.1 10.7 7.9 19.7 10.1 16.7 1.7 8.8 3.6 6.1 9.5 11.9 35.2 36.3 11.6 5.9 9.0 11.4 18.9 10.5 23.2 10.8 1.2 11.8 16.0 9.0 6.6 20.0 17.3 1.8 10.9 4.6 15.3 2.0 7.4 10.3 12.2 12.9 6.9 3.1 18.9 8.1 4.8 5.8 13.2 4.0 4.5 2.2 2.2 19.4 15.8 0.0 9.1 4.0 1.6 14.5 37.1 8.8 1.4 8.1 11.3 0.0 17.4 10.7 9.4 0.2 2.6 6.1 5.7 2.8 6.1 19.4 0.8 12.9 3.7 26.5 2.1 24.1 15.8 0.1 31.9 55.5 22.3 14.7 9.3 3.0 12.8 20.7 8.9 0.5 3.2 36.9 7.3 15.6 19.4 0.0 1.5 2.5 2.5 2.4 3.0 17.3 13.9 8.4 3.7 0.1 3.7 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.4 0.7 0.0 0.0 0.3 0.4 0.0 0.5 0.0 0.0 0.7 0.1 14.6 16.0 8.3 19.2 19.7 10.1 6.1 9.5 9.0 6.6 10.9 12.9 2.2 19.2 22.5 4.6 1.7 0.8 5.5 10.8 7.4 20.2 16.8 10.4 17.2 22.8 17.5 9.2 0.0 6.3 7.0 36.7 11.7 15.0 0.0 27.7 5.7 1.8 25.7 0.8 24.8 24.9 2.6 7.4 17.9 15.8 1.3 6.4 3.6 0.3 0.6 5.0 24.5 23.7 4.1 0.3 1.2 0.3 1.5 1.3 1.8 7.5 1.8 11.6 3.1 20.1 5.4 21.6 19.3 6.4 5.7 13.9 26.1 6.0 31.5 6.3 6.6 4.0 11.1 2.9 2.9 13.1 2.0 1.6 8.1 2.5 21.4 10.5 DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Distal enterocytes: 24.2;Endothelial cells: 48.6;Hepatic stellate cells: 30.4;Intestinal goblet cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BJ hTERT+: 59.4;HUVEC TERT2: 15.7;SCLC-21H: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" 25.2 2.6 6.9 2.9 6.1 0.3 21.2 6.5 7.0 8.0 4.9 7.6 4.0 8.8 1.0 3.7 7.6 3.7 23.8 5.8 6.0 10.0 3.5 22.5 5.0 7.1 6.5 4.1 2.9 2.9 5.6 19.8 7.5 7.9 3.0 0.9 4.3 2.7 10.0 5.5 6.8 4.2 6.6 4.6 4.8 1.5 8.4 5.0 15.4 10.6 1.7 8.7 7.6 6.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.9 59.4 0.2 0.3 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 0.4 1.1 0.1 0.1 0.0 0.6 0.0 0.9 0.0 1.4 0.5 1.6 0.0 0.1 32.5 0.0 0.3 0.7 0.0 0.0 0.0 3.5 0.9 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 6.1 6.5 7.0 5.8 6.0 7.1 6.5 7.5 6.6 8.4 6.2 70.7 0.0 2.7 0.0 1.7 1.3 0.2 0.2 4.0 4.9 1.6 2.8 3.2 1.5 0.9 0.0 0.0 1.5 0.2 24.2 0.0 0.2 0.2 1.9 0.7 48.6 17.4 0.0 0.9 0.2 0.6 3.1 13.3 2.6 2.5 0.0 30.4 0.1 0.2 0.0 0.6 36.3 6.1 1.6 0.8 0.3 0.0 0.8 1.8 11.2 0.0 0.2 0.0 0.5 0.5 0.2 16.7 0.0 3.5 2.3 9.2 0.0 0.2 1.4 0.0 0.9 3.8 0.8 2.0 1.0 1.6 1.9 0.4 0.4 12.0 0.6 DNAJC11 FLJ10737 ENSG00000007923 "DnaJ heat shock protein family (Hsp40) member C11" Q9NVH1 1 6634168-6701924 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023707, HPA028705" Uncertain Supported Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA023707: , HPA028705: AB_10603662" "unprognostic (3.74e-2)" "unprognostic (3.19e-2)" "unprognostic (4.06e-2)" "unprognostic (6.05e-3)" "unprognostic (9.55e-2)" "unprognostic (6.65e-2)" "unprognostic (4.38e-3)" "unprognostic (6.10e-2)" "unprognostic (6.34e-2)" "unprognostic (2.89e-1)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.30e-2)" "unprognostic (1.76e-1)" "unprognostic (9.77e-2)" "unprognostic (1.04e-1)" 16.9 28.3 15.8 19.1 16.3 14.5 16.3 14.5 20.0 15.2 11.9 28.6 27.2 17.2 12.7 24.2 15.5 12.5 37.2 17.7 15.1 54.5 28.8 13.6 19.0 17.9 16.5 18.7 19.0 24.5 12.7 17.7 18.1 15.4 31.7 16.5 17.1 13.8 44.0 20.3 23.3 17.6 13.5 23.3 21.7 16.5 17.8 15.4 14.6 35.9 18.5 18.6 16.2 17.7 44.5 41.5 47.6 44.3 40.5 28.6 44.7 42.6 36.5 82.7 58.9 51.2 61.7 70.0 41.2 49.2 35.3 58.1 82.9 69.1 72.1 40.0 57.6 71.0 84.1 51.4 40.7 85.4 37.6 42.3 19.0 74.8 48.7 29.2 39.6 52.2 92.6 29.7 42.3 35.5 53.6 45.1 49.9 60.2 71.9 60.0 41.7 50.9 53.0 37.3 64.9 46.0 49.3 98.2 55.4 39.9 39.1 44.6 40.5 48.9 26.1 40.9 51.7 34.5 40.7 91.2 48.1 93.5 25.0 10.2 9.6 3.4 8.7 12.8 8.8 7.5 6.2 9.4 12.1 8.4 6.6 5.2 0.3 10.0 14.4 5.3 7.6 9.2 15.8 16.3 14.5 20.0 17.7 15.1 17.9 16.5 18.1 13.5 17.8 17.7 11.9 9.6 11.8 17.3 9.7 19.6 4.4 9.1 4.6 18.5 8.6 9.8 9.7 2.8 9.7 12.9 29.2 21.4 5.3 33.4 35.2 14.2 14.9 8.6 13.1 9.3 14.6 25.2 28.6 13.7 22.8 10.3 23.0 10.5 5.1 27.4 5.0 14.1 16.7 20.2 35.8 22.9 14.2 8.2 24.2 9.3 8.1 9.6 28.4 18.7 8.4 11.8 6.2 15.6 23.3 11.1 19.6 4.5 13.3 6.5 37.2 32.4 12.0 17.7 6.6 11.8 13.7 17.0 11.6 14.5 18.3 23.8 8.9 24.9 36.4 5.3 DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 24.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 47.1;Distal enterocytes: 36.8;Exocrine glandular cells: 42.9;Hepatocytes: 44.6;Intestinal goblet cells: 26.9;Pancreatic endocrine cells: 27.6;Paneth cells: 26.2;Proximal enterocytes: 59.6;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 10.5;CACO-2: 19.1;EFO-21: 17.2;MCF7: 18.8;OE19: 18.6" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA039953: AB_2676770" "unprognostic (5.23e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-2)" "prognostic favorable (4.56e-5)" "unprognostic (4.77e-3)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "prognostic unfavorable (7.54e-4)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-2)" "unprognostic (9.35e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" 1.2 0.2 0.5 0.4 0.7 0.2 0.3 1.5 0.8 1.1 0.6 4.0 5.6 0.6 0.3 0.0 0.7 3.1 0.1 0.5 0.5 3.7 24.1 0.1 0.1 1.7 1.4 0.0 5.6 2.0 0.2 0.2 1.8 0.2 2.2 0.2 1.4 0.1 0.0 0.4 5.0 0.2 0.7 0.2 3.0 0.6 0.8 0.0 4.4 0.0 0.0 0.1 0.7 1.1 0.9 5.6 0.0 10.5 0.0 0.0 2.4 0.0 1.9 0.5 1.3 19.1 4.0 0.0 17.2 0.5 0.6 0.2 1.2 0.0 1.5 0.0 3.5 0.2 0.4 6.3 1.1 0.1 1.2 0.2 0.1 0.6 0.1 2.8 0.5 0.1 0.1 0.2 0.6 18.8 0.0 0.1 0.1 18.6 5.8 0.0 3.6 0.1 0.3 0.1 2.6 0.6 0.1 0.3 2.4 0.1 6.7 0.0 0.2 0.6 2.1 0.1 0.6 0.0 0.0 0.0 1.7 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.7 1.5 0.8 0.5 0.5 1.7 1.4 1.8 0.7 0.8 1.1 0.2 0.0 1.1 1.0 0.3 0.6 1.5 3.0 0.0 0.3 5.9 3.7 0.5 47.1 2.0 1.8 0.0 0.1 0.3 36.8 0.0 16.0 4.1 6.2 4.5 0.6 21.0 0.0 0.5 42.9 0.3 3.8 10.2 5.9 1.3 4.7 1.4 44.6 0.1 3.3 0.2 26.9 0.0 0.8 0.4 1.9 0.0 0.4 3.6 0.0 0.6 0.6 0.0 0.0 5.7 27.6 26.2 0.7 0.0 0.7 59.6 18.6 5.7 0.5 0.0 0.5 2.1 1.9 1.9 0.0 0.3 0.4 0.5 1.0 26.2 0.4 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 242.8;Paneth cells: 177.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Cytosol" "HPA054246: AB_2682427" "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favorable (8.91e-4)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 55.1 69.9 50.5 63.2 77.8 125.7 46.1 74.1 64.1 49.0 38.8 105.8 65.9 42.2 25.3 67.6 42.5 40.5 87.2 52.3 57.4 72.8 57.2 87.0 62.4 82.7 78.9 36.6 68.2 38.9 41.9 51.3 79.8 47.4 83.9 30.7 55.0 55.7 108.1 92.8 99.6 35.1 60.3 81.0 98.6 55.1 72.9 58.6 47.6 82.8 65.4 64.6 54.5 101.6 116.4 92.8 67.6 54.6 67.6 65.4 86.5 75.1 70.5 108.8 91.7 94.2 74.7 83.2 132.2 81.5 52.5 99.4 92.6 82.1 90.8 103.1 72.4 160.1 81.7 107.1 82.9 87.8 146.5 67.8 62.4 83.5 77.9 66.2 107.3 84.9 131.5 139.1 68.0 140.1 126.3 85.7 76.6 138.3 109.7 125.6 72.6 95.7 71.3 171.1 97.1 63.8 86.6 73.6 54.2 74.9 58.8 106.2 99.6 120.7 40.5 172.0 102.7 112.7 127.3 77.9 89.9 134.0 61.0 3.5 3.5 7.0 4.0 6.2 3.8 2.5 3.0 4.4 4.2 2.1 1.7 3.0 6.5 8.9 8.4 8.4 3.8 4.1 50.5 77.8 74.1 64.1 52.3 57.4 82.7 78.9 79.8 60.3 72.9 101.6 37.8 32.1 22.3 24.8 48.8 23.2 17.1 13.8 22.2 28.8 19.7 16.3 30.3 14.3 25.7 51.5 22.9 25.7 57.2 242.8 50.9 35.2 48.4 32.2 17.9 33.1 21.6 38.1 29.2 32.0 106.9 19.5 168.7 39.7 19.0 36.8 20.3 22.8 49.1 43.7 31.1 106.9 14.2 28.0 39.6 98.0 16.8 55.2 19.6 60.9 43.4 17.2 39.1 23.1 90.9 45.2 177.3 27.8 92.2 20.2 90.7 38.8 18.0 26.3 26.3 18.7 27.6 15.0 12.3 26.6 31.5 31.7 46.4 40.7 82.5 22.8 DOK4 FLJ10488 ENSG00000125170 "Docking protein 4" Q8TEW6 16 57471922-57487327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.9;Paneth cells: 99.9;Proximal enterocytes: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 94.2;CACO-2: 107.8;SH-SY5Y: 239.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008348, HPA055849" Supported Approved Cytosol NA No "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA008348: , HPA055849: AB_2682942" "unprognostic (3.44e-2)" "unprognostic (2.04e-2)" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (3.66e-1)" "unprognostic (9.71e-2)" "unprognostic (5.35e-2)" "unprognostic (1.39e-1)" "unprognostic (1.13e-2)" "unprognostic (3.00e-2)" "unprognostic (2.27e-2)" "unprognostic (1.53e-1)" "unprognostic (2.58e-3)" "unprognostic (4.30e-2)" "unprognostic (2.21e-1)" "unprognostic (4.42e-3)" "unprognostic (1.18e-3)" 10.5 9.2 12.0 9.6 12.2 1.8 8.8 12.2 12.7 20.7 9.0 43.9 46.1 16.9 12.1 32.8 15.2 17.5 14.8 11.1 11.8 42.0 33.7 23.3 4.3 8.3 11.0 19.8 17.6 12.0 19.8 10.9 13.0 18.3 31.3 4.1 12.6 25.8 3.0 43.2 49.9 12.2 7.5 10.5 37.3 7.0 10.8 3.8 10.7 3.9 7.4 16.7 21.6 9.4 10.3 94.2 15.0 26.8 20.6 22.6 16.7 17.7 23.5 12.4 3.8 107.8 53.1 1.1 75.4 37.2 7.3 21.0 9.2 4.9 5.3 2.7 6.9 22.3 28.2 63.2 29.3 0.3 2.3 15.8 14.2 16.4 1.8 27.6 19.0 3.8 7.3 4.3 14.9 9.9 1.1 4.1 9.6 46.1 4.0 8.9 7.8 1.2 64.8 3.9 73.6 239.9 14.5 6.3 4.5 66.0 5.6 4.2 20.5 2.1 15.1 6.1 0.8 2.9 4.1 0.8 6.7 4.7 9.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 12.0 12.2 12.2 12.7 11.1 11.8 8.3 11.0 13.0 7.5 10.8 9.4 8.3 12.8 14.0 0.7 1.4 7.9 7.2 3.6 5.2 15.5 3.7 5.0 2.4 30.0 3.3 14.7 0.0 0.9 1.8 127.9 5.9 15.0 1.2 2.1 5.3 11.3 3.6 1.3 5.0 23.7 7.6 7.9 36.2 2.9 0.0 19.6 6.8 20.4 0.9 8.4 7.1 30.3 2.0 0.8 1.6 2.0 13.4 1.0 3.6 1.0 0.7 2.2 0.0 2.0 0.4 30.8 99.9 12.0 1.4 7.1 96.6 46.9 2.5 0.8 6.6 1.1 6.9 0.2 4.1 11.6 18.0 0.5 2.5 4.8 34.1 6.1 DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 105.3;parathyroid gland: 157.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.6;Pancreatic endocrine cells: 254.9;Undifferentiated cells: 216.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 8.4" "Lineage enriched" "Detected in single" 13 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 172.9;HaCaT: 269.2;HBEC3-KT: 201.2;hTERT-HME1: 212.1;OE19: 229.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004896, CAB025122" Enhanced Supported "Cell Junctions" NA NA 140000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "CAB025122: , HPA004896: AB_1078643" "unprognostic (1.56e-3)" "prognostic unfavorable (8.22e-4)" "prognostic favorable (7.81e-4)" "unprognostic (8.77e-3)" "unprognostic (3.53e-4)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (4.94e-5)" "unprognostic (3.40e-1)" "prognostic favorable (3.14e-10)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (8.57e-3)" 23.6 1.2 0.2 14.6 0.2 0.8 40.2 0.6 0.2 13.0 26.4 105.3 79.1 8.6 10.6 10.2 22.4 31.4 31.4 0.7 0.1 33.8 15.1 15.0 1.6 0.3 0.5 13.6 39.5 157.8 1.6 22.9 0.7 31.5 100.0 0.3 68.6 6.5 1.2 6.7 84.6 7.3 0.0 0.4 77.1 3.7 0.4 24.2 42.2 0.7 4.6 41.6 5.7 0.5 119.2 45.3 4.0 0.1 0.6 7.2 143.0 0.0 0.0 0.3 0.0 31.7 172.9 0.0 64.2 0.0 54.4 269.2 54.7 201.2 0.0 0.2 33.9 0.1 46.7 35.9 20.2 15.2 0.3 9.9 136.7 4.2 212.1 102.4 0.0 34.7 47.8 0.2 0.0 31.5 32.2 2.0 55.4 229.5 23.1 52.8 0.0 76.2 65.8 58.5 23.9 0.2 88.3 61.8 0.3 117.8 44.3 12.7 0.1 0.2 25.0 0.3 29.3 5.7 0.2 0.2 19.8 0.1 25.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.2 0.6 0.2 0.7 0.1 0.3 0.5 0.7 0.0 0.4 0.5 120.8 54.5 45.4 0.0 1.3 13.5 79.4 76.2 28.5 0.4 68.9 49.3 57.3 101.5 79.6 12.9 0.0 80.1 4.4 404.6 3.9 105.5 1.0 48.6 9.4 13.1 79.9 9.0 3.3 76.1 116.2 12.0 70.3 82.1 4.5 18.8 2.2 26.4 10.3 1.7 0.3 165.7 79.3 0.8 4.0 2.5 1.5 2.2 17.8 0.0 6.3 5.3 1.0 0.5 0.1 254.9 152.0 0.4 0.3 133.5 145.1 10.0 75.4 0.7 0.0 0.6 8.2 2.7 8.9 23.1 6.0 59.9 2.6 6.6 216.8 179.9 DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208588 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 33.6;Oligodendrocytes: 33.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 63.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 62.8;CACO-2: 34.5;CAPAN-2: 37.7;OE19: 35.4;RT4: 95.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA056760: AB_2683228, HPA059294: AB_2683969" "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (4.97e-2)" "unprognostic (5.03e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (3.04e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (5.51e-2)" "unprognostic (2.51e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.57e-3)" 10.4 1.9 13.9 5.5 21.2 9.3 9.5 21.4 20.0 8.0 8.2 17.5 16.4 3.8 1.9 4.7 5.8 4.9 3.2 13.2 21.2 8.5 32.5 18.1 5.3 30.2 22.4 15.0 7.9 1.0 4.1 14.8 27.0 7.5 17.2 10.4 21.7 3.1 1.4 3.9 14.4 2.5 33.5 6.7 11.6 1.7 25.6 1.5 10.2 1.7 6.5 15.0 3.9 50.5 4.8 5.7 30.5 0.6 8.5 0.5 62.8 0.4 2.7 0.3 0.4 34.5 37.7 11.6 2.1 0.7 1.2 16.5 9.5 11.8 0.1 0.8 0.5 0.1 6.6 11.2 2.4 0.9 2.3 1.4 19.3 0.1 0.5 2.1 0.0 2.1 0.1 1.1 1.4 2.7 0.5 0.1 16.1 35.4 1.5 4.1 27.1 1.3 2.6 95.2 0.0 0.1 24.3 6.4 0.8 7.7 4.9 0.5 0.3 0.1 4.9 0.1 0.0 0.4 0.1 1.1 0.2 2.8 2.6 0.7 0.4 0.4 0.0 0.4 0.0 1.0 0.0 0.0 0.6 1.3 0.0 0.0 1.5 0.0 0.2 2.8 0.0 0.1 13.9 21.2 21.4 20.0 13.2 21.2 30.2 22.4 27.0 33.5 25.6 50.5 8.9 19.2 16.8 9.4 3.1 1.7 3.2 7.9 2.2 2.0 2.9 3.9 1.4 28.6 21.8 7.3 0.0 15.0 6.9 33.6 0.0 10.2 0.4 1.5 8.1 3.6 4.9 0.0 12.0 4.9 19.2 7.2 12.2 3.0 1.3 4.9 5.7 23.1 3.7 0.0 8.4 10.5 2.0 2.5 2.5 0.4 4.1 2.7 5.4 3.7 0.9 30.3 0.0 7.5 33.9 10.8 16.3 3.4 0.0 3.1 19.8 9.1 14.9 2.0 0.0 22.1 3.6 0.4 1.7 1.8 1.3 5.5 1.2 5.9 18.5 22.5 DUS1L "DUS1, PP3111" ENSG00000169718 "Dihydrouridine synthase 1 like" Q6P1R4 17 82057506-82065887 "Predicted intracellular proteins" "tRNA processing" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023384 Uncertain Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA023384: AB_1847879" "unprognostic (4.42e-2)" "unprognostic (2.19e-2)" "unprognostic (4.30e-2)" "unprognostic (3.03e-2)" "unprognostic (1.73e-3)" "unprognostic (1.84e-1)" "unprognostic (4.01e-2)" "unprognostic (5.17e-2)" "unprognostic (1.10e-1)" "unprognostic (4.16e-3)" "unprognostic (5.23e-3)" "unprognostic (3.13e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (4.17e-2)" "unprognostic (8.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.70e-3)" 83.3 86.7 38.2 51.1 38.0 94.2 89.0 35.2 49.7 85.3 40.6 101.3 66.6 74.0 23.0 117.8 81.8 27.0 93.1 38.4 34.9 90.4 174.3 80.5 64.8 40.4 36.4 82.3 148.3 32.0 99.7 27.0 37.0 118.8 29.8 16.9 105.8 30.4 144.3 127.1 107.2 18.9 35.2 131.3 119.4 93.6 38.5 37.7 93.6 27.3 33.3 87.9 85.0 38.6 169.4 109.0 37.7 44.3 28.9 28.4 115.0 57.5 26.8 56.5 40.2 99.7 77.9 133.7 65.3 33.0 39.8 112.0 46.1 60.9 21.9 54.6 263.1 89.2 167.3 178.8 65.3 138.8 101.0 43.1 75.1 37.3 46.4 27.0 64.1 124.8 147.1 69.4 28.5 268.6 192.9 114.9 43.7 87.6 151.7 143.7 43.1 151.7 42.3 114.3 193.9 118.7 45.2 192.6 127.1 35.8 112.3 133.1 49.1 91.7 89.0 79.3 150.1 164.5 48.9 113.0 58.8 102.2 65.0 3.0 3.5 5.0 4.0 3.9 6.0 3.9 4.0 5.0 3.6 3.3 6.5 5.6 1.2 5.9 5.3 7.9 7.6 2.0 38.2 38.0 35.2 49.7 38.4 34.9 40.4 36.4 37.0 35.2 38.5 38.6 36.8 28.9 19.1 17.6 30.0 22.0 20.0 10.0 10.8 28.3 78.3 69.8 21.3 24.3 15.0 11.0 29.2 16.1 60.1 65.2 7.9 12.1 87.2 30.5 28.4 21.0 43.2 21.7 15.9 39.1 19.1 19.1 37.2 37.6 3.8 46.3 13.9 77.8 21.0 18.5 15.8 58.1 8.2 26.8 14.3 146.2 14.3 27.0 10.6 10.3 19.2 17.8 27.8 10.1 18.2 32.0 32.2 13.5 33.7 40.9 32.4 24.5 15.3 47.8 13.1 18.0 23.9 43.3 9.6 23.3 28.4 15.6 28.4 52.2 75.4 37.5 DVL1 ENSG00000107404 "Dishevelled segment polarity protein 1" O14640 1 1335276-1349418 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 230.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "PC-3: 154.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011538, HPA073607" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB011538: AB_2093326, HPA073607: " "unprognostic (2.67e-1)" "unprognostic (4.34e-3)" "unprognostic (2.13e-3)" "unprognostic (2.05e-2)" "unprognostic (9.58e-2)" "unprognostic (1.51e-1)" "unprognostic (2.81e-3)" "unprognostic (5.03e-3)" "unprognostic (1.78e-2)" "unprognostic (2.96e-2)" "unprognostic (1.62e-3)" "unprognostic (5.35e-2)" "unprognostic (4.03e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-4)" "unprognostic (2.34e-2)" "unprognostic (2.55e-2)" 32.8 49.9 50.6 11.8 44.4 9.6 34.0 32.0 71.4 42.9 23.1 50.4 28.8 37.6 8.3 65.0 42.7 11.7 74.9 51.6 31.9 38.2 56.8 35.4 9.5 42.2 37.7 43.0 63.9 21.2 43.7 15.0 35.4 39.4 5.8 8.1 61.8 14.3 230.1 51.5 32.4 7.9 31.9 28.9 53.1 61.9 37.9 6.8 38.3 69.9 4.7 43.6 46.2 41.1 81.5 40.7 16.5 35.2 15.7 19.1 40.5 48.3 22.8 37.3 18.7 31.7 99.3 25.3 70.8 21.5 20.6 48.9 13.2 49.1 5.8 31.4 76.6 14.4 78.4 58.1 33.6 22.5 21.7 16.3 29.6 50.2 34.2 31.7 12.9 33.9 56.5 17.5 15.6 32.6 21.8 37.4 26.3 29.0 154.3 36.9 13.0 44.7 27.5 12.6 64.3 43.8 23.3 62.6 66.6 5.9 34.8 37.4 25.8 21.2 55.0 82.4 82.2 27.6 12.1 32.1 62.2 31.3 13.7 0.1 0.3 0.0 0.2 0.3 0.2 0.3 0.2 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.2 0.3 0.1 0.1 50.6 44.4 32.0 71.4 51.6 31.9 42.2 37.7 35.4 31.9 37.9 41.1 20.5 19.2 14.8 12.1 4.4 13.8 5.5 8.8 6.2 33.2 19.0 16.3 25.5 8.6 10.1 7.3 6.2 10.7 6.9 32.1 3.9 11.3 1.1 13.4 14.2 12.0 12.1 1.3 11.0 20.4 14.9 11.5 31.6 18.8 1.3 15.8 6.1 21.8 5.1 32.0 10.2 17.6 4.1 5.7 6.8 3.0 13.1 4.9 7.2 9.4 2.6 23.5 1.0 6.0 14.3 52.3 20.8 10.5 5.1 16.6 21.0 5.8 9.1 22.1 13.1 12.2 10.8 14.2 13.3 15.3 15.5 11.4 4.5 25.4 24.3 12.6 DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 133.1;Horizontal cells: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: AB_2683271" "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" 9.9 4.6 2.9 14.2 3.3 14.9 6.3 2.3 6.1 7.8 3.2 25.7 20.4 13.1 6.2 10.7 10.0 14.3 24.4 8.6 2.3 4.7 4.2 9.1 21.6 3.4 2.3 8.7 8.6 4.9 3.0 14.1 2.7 6.5 21.9 14.8 5.4 8.8 39.4 7.5 28.0 13.0 3.1 14.7 20.6 5.0 2.7 24.1 6.9 10.4 14.2 11.9 7.6 3.5 24.5 13.4 19.8 14.4 9.7 13.2 15.8 24.2 15.7 11.6 6.6 17.9 13.2 45.3 29.2 35.3 7.1 27.8 16.0 9.6 12.4 19.6 20.9 7.3 9.5 6.9 3.8 16.8 15.2 11.0 13.3 31.4 24.8 19.6 6.6 18.9 9.2 22.9 15.1 13.9 14.4 8.2 17.2 15.8 21.5 37.9 19.7 20.0 13.6 30.2 26.0 30.7 10.1 13.4 13.9 13.3 9.2 13.9 10.0 18.4 17.3 12.8 19.4 10.9 1.9 24.9 17.6 11.1 19.4 2.0 0.3 4.0 3.2 0.7 2.3 1.8 2.3 4.2 1.2 2.0 1.9 3.7 0.4 4.7 0.9 0.5 2.0 1.1 2.9 3.3 2.3 6.1 8.6 2.3 3.4 2.3 2.7 3.1 2.7 3.5 13.0 9.6 10.2 3.9 14.4 11.3 11.9 6.7 8.6 18.0 7.4 8.1 44.5 20.0 11.2 1.8 22.9 3.5 28.6 133.1 0.0 19.0 0.6 28.0 35.9 12.1 24.6 4.8 11.0 18.2 7.9 18.9 25.0 15.6 5.7 13.3 6.4 6.1 17.0 80.8 11.4 62.0 4.1 15.7 22.5 2.0 11.5 15.5 8.8 13.1 12.0 16.7 42.2 6.0 9.1 17.7 61.3 13.2 9.0 16.1 62.9 11.3 30.3 23.3 13.1 53.5 33.6 2.7 10.1 15.6 16.2 4.5 31.0 17.9 32.3 34.4 E4F1 E4F ENSG00000167967 "E4F transcription factor 1" Q66K89 16 2223580-2235742 "Enzymes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052042, HPA069007, HPA071325, HPA072309" Enhanced Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA052042: AB_2681705, HPA069007: , HPA071325: AB_2686390, HPA072309: " "unprognostic (3.05e-1)" "prognostic favorable (9.13e-4)" "unprognostic (7.31e-2)" "unprognostic (4.57e-3)" "unprognostic (2.89e-1)" "prognostic favorable (1.10e-4)" "unprognostic (9.16e-2)" "unprognostic (4.23e-2)" "unprognostic (3.08e-1)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (8.49e-3)" "prognostic unfavorable (5.50e-4)" "unprognostic (1.85e-1)" "unprognostic (1.03e-1)" "unprognostic (5.12e-1)" "unprognostic (8.93e-3)" 13.5 16.0 7.9 6.6 8.6 11.3 15.1 10.2 13.5 17.5 4.8 16.5 6.2 18.7 1.9 16.1 15.2 3.3 15.3 8.1 7.0 16.1 19.0 13.4 6.8 10.2 8.1 15.9 15.2 4.4 19.0 5.3 10.0 21.3 1.8 3.0 16.0 5.5 19.0 23.6 15.0 2.7 6.1 20.5 14.8 14.4 8.3 6.4 22.6 4.3 2.8 16.1 16.4 9.4 10.9 20.2 8.3 16.4 4.8 4.4 20.0 14.8 6.6 10.0 6.7 32.7 16.2 15.8 15.8 5.7 5.6 14.6 6.8 7.6 1.8 17.2 25.6 11.2 36.1 18.0 9.3 14.2 19.1 6.6 8.5 9.0 4.1 5.6 6.9 13.5 26.7 10.6 3.8 30.1 18.8 30.6 18.7 6.6 18.8 34.7 9.1 27.9 6.2 7.6 21.4 15.5 18.4 21.9 10.7 3.0 19.4 20.0 12.3 12.0 15.7 12.0 12.4 20.7 10.9 32.0 5.0 10.0 12.3 6.8 8.1 11.7 10.2 9.8 8.8 8.2 8.4 9.7 8.8 8.0 9.0 8.4 11.4 6.9 11.8 5.2 11.4 7.5 7.9 8.6 10.2 13.5 8.1 7.0 10.2 8.1 10.0 6.1 8.3 9.4 9.1 16.0 8.2 8.5 14.4 7.1 7.9 12.2 9.1 13.8 12.3 10.8 4.9 5.7 13.9 11.0 37.5 20.4 18.5 26.5 11.7 11.1 19.6 12.6 10.2 10.3 25.8 6.5 8.1 10.5 17.2 8.7 31.1 11.6 2.5 12.3 6.8 10.5 12.6 30.3 7.2 19.8 20.3 7.3 7.8 5.0 11.5 7.3 7.2 10.3 9.1 11.3 13.4 5.0 5.5 11.1 14.5 16.1 13.2 9.7 15.4 8.0 12.0 15.7 13.1 9.6 11.2 19.0 16.1 7.6 8.9 13.4 11.8 12.6 15.3 6.4 ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345572 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 29.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 673.8;TIME: 588.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced NA NA 1300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" 87.3 123.2 26.5 47.7 29.4 48.1 79.4 23.0 30.1 61.4 12.6 71.0 30.1 42.4 10.0 26.7 46.9 36.8 70.9 21.3 33.7 38.1 54.0 72.1 35.7 34.4 25.7 71.0 91.8 125.0 47.4 66.5 30.4 53.1 34.7 14.7 33.6 25.1 19.8 34.3 46.1 42.3 21.2 48.5 43.3 22.7 28.1 21.1 51.4 33.2 34.9 58.8 43.8 27.5 93.0 60.1 77.9 38.3 111.0 116.4 44.1 135.4 236.8 72.9 66.6 44.1 275.8 34.0 323.6 138.8 157.7 38.4 32.6 64.9 63.5 83.0 27.2 48.7 89.9 34.8 144.3 7.1 11.8 61.6 74.3 112.6 55.8 199.2 673.8 27.6 10.0 17.7 62.9 19.4 14.6 11.4 23.2 26.3 46.5 17.5 45.0 49.2 114.0 17.0 26.4 63.1 134.3 79.2 57.4 42.5 55.9 20.2 588.7 160.7 77.9 73.3 79.9 26.4 49.0 39.1 332.6 16.5 196.6 0.2 8.4 3.3 2.9 10.0 4.2 6.1 6.1 4.6 0.7 4.1 4.0 2.7 29.8 1.5 7.8 2.8 8.6 7.2 26.5 29.4 23.0 30.1 21.3 33.7 34.4 25.7 30.4 21.2 28.1 27.5 164.0 19.2 7.5 46.4 25.1 20.3 19.7 81.6 18.8 5.0 71.3 44.7 18.9 10.0 54.7 23.9 0.0 6.0 12.4 105.8 5.9 25.8 1.5 19.6 35.2 106.1 25.2 20.2 19.2 56.7 35.0 51.8 20.9 51.8 18.4 35.4 97.1 36.0 3.3 0.0 14.8 13.0 57.0 9.6 14.3 4.2 43.5 17.3 7.2 31.9 25.5 50.4 8.2 13.6 22.5 100.4 106.5 55.3 29.4 34.9 45.7 7.5 24.2 4.4 39.5 72.7 47.5 1.3 5.9 8.5 16.1 10.5 17.9 80.6 21.6 40.8 EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 239.7;Hepatic stellate cells: 187.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.5;OE19: 45.5;SH-SY5Y: 42.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" 20.7 6.1 3.8 4.3 5.9 0.2 17.1 1.3 6.2 11.0 0.0 22.1 7.9 10.2 0.7 12.1 8.8 4.2 15.5 5.5 4.9 11.2 4.8 23.4 3.2 0.1 0.1 7.2 3.9 3.2 6.3 15.4 0.3 12.5 9.9 3.2 14.0 10.6 6.5 17.2 14.4 5.5 0.1 7.4 15.0 5.4 1.6 3.6 11.9 8.0 3.2 6.5 14.1 4.3 23.3 1.8 76.5 0.1 0.2 0.7 0.3 10.8 5.4 8.2 4.7 19.1 28.7 0.0 11.0 2.5 0.6 28.4 2.9 10.9 8.9 0.0 24.3 0.1 6.0 0.0 1.5 6.9 0.6 3.5 19.0 0.4 16.1 4.1 10.4 0.2 0.1 0.0 9.1 3.3 0.2 0.1 4.7 45.5 5.0 21.9 3.3 0.1 11.9 2.5 5.8 42.7 3.6 1.7 0.1 21.4 1.0 0.2 9.6 16.3 0.0 0.5 23.8 0.4 0.0 0.0 34.5 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 5.9 1.3 6.2 5.5 4.9 0.1 0.1 0.3 0.1 1.6 4.3 239.7 6.4 35.7 38.8 4.4 83.2 52.9 15.4 13.1 10.4 39.8 45.3 8.8 5.7 13.2 25.8 0.0 1.4 8.6 114.6 0.0 6.8 0.4 24.7 69.8 106.5 50.6 0.0 49.3 1.4 3.1 15.4 69.3 42.1 17.8 11.8 187.4 1.3 1.1 6.7 29.7 59.8 26.4 5.8 11.9 1.0 0.3 4.0 32.0 48.7 0.0 89.1 0.0 3.5 13.9 46.3 64.3 0.4 1.0 25.1 15.9 0.2 8.7 3.4 0.0 33.1 22.8 0.7 3.3 41.1 86.0 1.9 7.9 6.4 71.5 72.0 EHBP1L1 "DKFZp762C186, TANGERIN" ENSG00000173442 "EH domain binding protein 1 like 1" Q8N3D4 11 65576046-65592650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 255.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.1;Kupffer cells: 79.7;Macrophages: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039479, HPA073476" Enhanced Approved "Vesicles,Plasma membrane" NA NA 110000 "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Plasma membrane" "HPA039479: AB_10795678, HPA073476: " "unprognostic (1.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.84e-1)" "unprognostic (2.41e-3)" "unprognostic (2.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.36e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.10e-3)" "unprognostic (5.02e-2)" "unprognostic (3.50e-2)" "unprognostic (1.10e-1)" 27.2 9.9 7.5 51.9 6.2 59.7 21.5 5.9 9.4 35.9 7.3 108.1 26.0 56.1 5.7 45.4 48.0 18.0 45.6 7.1 6.3 17.7 10.8 39.6 30.7 9.8 8.1 19.6 8.1 4.1 9.8 16.3 7.7 45.2 12.2 0.4 22.9 39.5 255.7 22.6 46.6 32.8 8.0 73.3 41.0 7.3 9.4 14.5 13.0 70.7 16.6 71.3 40.8 9.0 40.6 41.0 1.3 21.8 10.5 26.4 8.2 31.4 22.9 14.8 7.8 13.7 34.9 14.0 52.4 45.8 41.2 55.9 7.6 29.7 3.4 39.3 1.2 32.4 51.0 12.0 10.0 7.1 30.1 22.7 19.8 37.2 6.8 26.9 15.2 20.8 50.5 55.9 13.8 34.5 12.4 27.5 1.8 15.1 34.8 33.6 0.2 46.8 13.7 20.0 0.9 17.2 17.4 15.2 32.9 3.0 21.9 33.7 26.3 40.3 42.9 57.3 0.6 98.5 66.6 7.3 60.2 18.8 23.9 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 7.5 6.2 5.9 9.4 7.1 6.3 9.8 8.1 7.7 8.0 9.4 9.0 33.1 0.0 6.9 6.2 23.9 10.1 8.5 2.9 15.9 1.4 12.2 14.2 22.0 7.2 7.4 1.8 0.0 3.4 27.3 79.1 0.0 3.6 0.2 11.9 12.2 26.0 4.2 61.6 4.4 5.1 1.4 13.8 61.2 14.2 2.5 5.3 18.9 5.7 32.6 0.0 2.2 16.3 2.0 79.7 33.9 1.7 11.5 67.6 7.2 15.0 49.1 0.7 20.6 1.5 1.3 27.8 53.0 38.0 19.5 11.6 19.5 0.4 8.6 1.1 26.3 27.3 30.7 2.7 5.9 15.3 14.8 2.6 23.2 23.0 21.9 17.0 EIF4G1 "EIF4F, EIF4G, p220, PARK18" ENSG00000114867 "Eukaryotic translation initiation factor 4 gamma 1" Q04637 3 184314495-184335358 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding, Translational shunt" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 348.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014774, HPA028487, HPA043866" Approved Enhanced Cytosol NA NA 330000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB014774: , HPA028487: AB_10602219, HPA043866: AB_2678705" "unprognostic (4.14e-3)" "unprognostic (2.10e-2)" "unprognostic (6.01e-2)" "unprognostic (3.01e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (4.27e-3)" "unprognostic (2.35e-1)" "unprognostic (1.54e-1)" "unprognostic (1.55e-3)" "unprognostic (7.06e-3)" "unprognostic (2.42e-1)" "unprognostic (7.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.33e-3)" 86.2 91.8 24.8 75.7 22.2 84.0 69.0 17.9 22.2 66.6 34.1 81.8 62.0 71.3 32.7 126.8 59.6 50.9 90.8 23.3 29.8 53.9 113.0 74.2 55.7 38.5 36.1 57.5 96.2 99.3 57.4 59.4 32.4 62.2 56.5 22.3 93.1 59.2 348.3 116.7 67.2 74.7 24.4 58.2 79.9 64.8 37.4 49.1 71.3 177.0 63.2 76.0 85.3 16.6 559.0 232.3 173.1 205.7 196.9 192.5 322.5 298.6 204.1 315.4 238.8 486.5 173.7 348.4 381.9 367.6 358.5 292.7 322.6 365.8 230.5 375.1 345.8 321.3 226.1 206.4 173.4 321.4 212.2 199.6 206.8 292.4 268.8 152.8 278.3 128.8 239.6 267.2 205.7 403.4 219.7 105.3 368.9 241.3 180.8 221.7 183.4 281.9 156.8 331.8 197.7 174.6 258.1 415.6 187.6 144.6 445.2 206.5 364.1 227.2 228.9 297.3 567.9 203.8 263.2 629.0 260.5 271.4 258.3 8.3 16.0 6.7 11.7 14.4 10.8 7.7 7.8 9.6 12.8 9.2 6.9 7.6 5.6 8.7 21.0 18.1 6.0 12.7 24.8 22.2 17.9 22.2 23.3 29.8 38.5 36.1 32.4 24.4 37.4 16.6 63.9 76.9 72.6 23.8 41.7 59.1 78.2 58.0 70.6 24.2 69.3 46.2 109.4 50.1 72.3 62.5 14.6 64.0 37.6 135.5 13.7 98.8 151.6 53.0 67.1 69.3 55.7 82.7 10.8 135.3 74.8 64.5 75.4 85.6 48.0 163.8 43.5 152.8 66.8 21.9 12.9 97.2 50.8 40.8 39.9 202.7 73.0 48.9 33.8 14.0 53.0 23.2 30.9 4.0 10.1 149.0 69.0 56.1 112.9 96.8 77.0 45.4 51.4 23.2 78.9 81.6 78.9 24.8 41.4 120.7 91.8 79.6 46.0 94.8 108.4 95.6 EIF5AL1 "bA342M3.3, EIF5AP1" ENSG00000253626 "Eukaryotic translation initiation factor 5A like 1" Q6IS14 10 79512533-79516440 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 10.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.2;Intestinal goblet cells: 96.7;Spermatocytes: 76.5;Undifferentiated cells: 121.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "U-251 MG: 2.2" HPA074052 Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Plasma membrane" "HPA074052: " "unprognostic (2.16e-2)" "prognostic favorable (4.23e-4)" "unprognostic (2.55e-1)" "unprognostic (4.14e-3)" "unprognostic (1.50e-1)" "unprognostic (3.48e-2)" "unprognostic (4.25e-2)" "unprognostic (2.50e-3)" "unprognostic (2.04e-2)" "unprognostic (3.57e-1)" "unprognostic (1.01e-1)" "unprognostic (8.79e-3)" "unprognostic (1.56e-1)" "unprognostic (8.63e-2)" "unprognostic (1.87e-1)" "unprognostic (6.68e-2)" "unprognostic (1.81e-1)" 0.8 0.8 0.1 0.2 0.1 0.2 0.6 0.5 0.3 0.4 0.0 0.6 0.2 0.5 0.2 1.4 0.4 0.0 0.9 0.1 0.0 0.5 1.3 0.6 0.3 0.0 0.0 0.3 0.7 0.2 0.4 0.0 0.0 0.5 0.2 0.8 0.5 0.0 1.5 1.0 0.5 0.0 0.0 0.5 0.5 10.6 0.0 0.0 0.5 0.0 0.3 0.5 0.7 0.1 0.4 0.8 0.3 1.7 0.0 0.2 0.3 0.3 0.1 0.3 0.2 0.6 0.3 0.9 0.3 0.0 0.2 0.5 0.1 0.0 0.2 0.2 0.7 0.2 1.0 0.4 0.1 0.3 0.6 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.3 0.1 0.6 1.0 0.9 1.2 0.1 0.1 0.3 0.7 0.6 0.5 0.8 0.2 0.5 0.5 0.4 0.6 0.1 0.8 0.7 0.2 0.4 1.0 1.1 2.2 0.4 0.5 0.8 0.7 0.2 0.6 1.1 0.8 0.6 1.2 2.0 1.4 1.3 1.2 1.3 1.6 1.3 0.9 1.3 0.7 1.7 1.3 2.5 1.0 0.8 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 16.0 30.0 1.3 10.4 33.8 3.0 7.8 0.0 0.6 5.1 2.4 43.1 2.8 16.1 0.0 0.0 20.8 2.4 79.2 11.7 64.5 14.7 2.9 4.4 12.9 60.0 10.7 0.6 47.8 35.1 15.5 0.0 3.2 48.2 0.9 4.2 5.1 17.5 1.7 0.6 96.7 8.2 8.7 27.9 8.7 5.0 7.2 19.6 0.0 41.9 1.2 13.4 0.0 1.0 65.6 61.2 3.0 0.5 10.3 66.5 11.1 6.1 0.5 0.0 6.9 25.9 76.5 4.3 0.0 34.5 27.6 8.9 3.3 121.3 5.0 ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Paneth cells: 50.3;Proximal enterocytes: 100.3;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.1;CAPAN-2: 49.3;HaCaT: 46.9;T-47d: 45.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "HPA021484: AB_1848129" "unprognostic (4.49e-3)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.16e-3)" "unprognostic (3.14e-1)" "unprognostic (8.17e-3)" "unprognostic (1.73e-1)" "unprognostic (8.06e-2)" "unprognostic (3.40e-2)" "unprognostic (6.95e-3)" "prognostic favorable (2.77e-5)" "unprognostic (3.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (1.97e-2)" 2.8 1.8 1.5 4.3 1.4 5.6 8.8 2.4 2.6 6.4 0.3 24.3 33.1 2.0 4.1 25.8 8.5 8.6 1.9 1.1 1.7 21.4 8.1 8.3 2.9 2.1 1.0 1.8 41.0 8.5 29.8 7.1 2.8 19.3 9.1 0.7 20.3 9.6 1.2 33.5 26.3 0.8 0.4 5.6 26.0 13.0 1.3 2.1 19.3 0.3 2.6 8.5 13.2 1.5 22.1 2.5 2.4 3.0 0.4 0.6 33.1 1.3 0.7 1.6 1.4 14.2 49.3 3.0 1.5 0.7 0.7 46.9 2.2 21.6 0.3 1.4 2.9 3.2 4.8 4.7 1.0 1.9 7.5 0.5 15.6 1.2 1.1 1.6 1.7 2.6 3.1 1.5 0.9 18.4 2.0 9.3 3.2 20.7 1.9 4.6 2.3 4.9 2.0 2.9 16.2 3.6 3.2 14.4 1.5 1.3 45.8 3.4 2.8 3.7 4.5 2.3 2.3 4.9 1.7 5.8 1.9 4.4 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 1.5 1.4 2.4 2.6 1.1 1.7 2.1 1.0 2.8 0.4 1.3 1.5 1.8 0.0 13.1 0.0 2.0 8.8 11.9 21.9 13.1 0.9 20.6 16.3 1.2 15.7 12.6 20.2 0.0 33.8 1.0 63.9 17.6 20.1 22.9 8.8 1.7 1.6 13.1 6.9 0.4 24.0 15.0 1.7 47.4 12.2 4.5 1.3 1.4 3.6 3.6 0.0 0.3 33.8 22.4 1.6 3.1 36.3 0.9 2.6 3.6 1.9 2.8 0.4 0.0 0.0 1.0 24.8 50.3 0.7 1.4 7.9 100.3 28.6 12.3 1.5 0.0 0.4 1.6 14.5 5.9 14.4 13.5 16.8 2.3 5.0 52.3 13.0 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase Q8NFI3 17 79074824-79088599 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021551 Enhanced Approved Centrosome,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Centrosome "HPA021551: AB_1848156" "unprognostic (7.49e-2)" "unprognostic (1.42e-1)" "unprognostic (5.65e-2)" "unprognostic (6.16e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-3)" "unprognostic (9.62e-2)" "unprognostic (4.09e-2)" "unprognostic (9.07e-2)" "unprognostic (7.00e-3)" "prognostic favorable (2.60e-4)" "unprognostic (4.79e-2)" "prognostic unfavorable (8.97e-6)" "unprognostic (8.38e-3)" "unprognostic (6.03e-1)" "unprognostic (2.06e-2)" "prognostic favorable (8.73e-5)" 9.3 8.4 8.4 8.2 9.4 7.2 9.1 8.6 11.5 11.9 10.2 14.5 14.3 9.6 2.0 5.4 10.7 5.9 9.1 8.3 9.9 7.6 8.8 9.4 9.2 10.0 10.7 13.7 7.9 6.7 7.1 5.6 10.1 10.8 9.2 6.1 9.1 4.3 24.0 9.6 14.9 5.2 8.4 20.0 11.0 3.4 11.0 7.2 11.8 10.4 5.8 11.6 9.5 12.3 6.3 12.8 5.7 10.0 4.4 2.5 9.6 5.6 3.5 4.6 3.9 7.2 6.4 0.0 5.9 5.1 6.2 9.7 7.2 5.4 2.3 4.3 12.5 5.9 14.8 4.2 4.2 6.7 11.2 5.8 7.9 3.4 3.3 7.8 4.9 14.7 9.1 3.6 2.5 5.1 0.6 7.3 2.7 15.4 12.1 12.7 16.8 5.3 2.4 16.4 4.2 9.2 7.3 33.5 4.2 6.8 10.8 7.8 6.4 6.8 6.1 6.4 4.4 10.9 1.9 2.9 4.0 13.6 5.1 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.2 0.5 0.1 0.0 0.4 0.1 0.0 0.7 0.1 8.4 9.4 8.6 11.5 8.3 9.9 10.0 10.7 10.1 8.4 11.0 12.3 6.9 0.0 16.0 18.3 6.1 4.5 5.6 3.4 3.4 11.1 7.5 7.4 6.3 5.7 5.7 11.0 35.5 5.3 7.1 23.3 0.0 4.2 1.8 3.9 6.3 7.6 26.2 3.8 5.4 4.3 5.4 6.7 18.8 4.8 5.1 11.5 8.2 11.5 8.6 8.4 10.1 18.6 0.0 13.2 9.8 1.3 3.4 15.5 0.0 14.0 8.8 5.3 6.2 3.5 11.0 2.5 10.7 1.9 5.7 5.3 16.5 2.9 2.9 24.5 13.1 7.9 8.3 1.9 1.6 4.1 5.8 6.7 7.4 7.5 27.5 4.4 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 107.2;kidney: 95.2;liver: 263.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 209.3;Hepatocytes: 134.8;Intestinal goblet cells: 77.1;Proximal enterocytes: 87.0" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.3" "Cell line enhanced" "Detected in all" "RT4: 57.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" NA NA 5900000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 8.2 7.7 5.0 11.4 7.3 8.0 12.4 7.1 6.7 7.3 7.1 94.6 72.1 6.3 7.7 11.3 5.7 12.1 7.7 5.1 6.3 95.2 263.7 6.5 5.5 7.6 7.3 6.7 4.9 7.7 5.0 5.6 7.8 37.7 107.2 9.4 10.7 4.4 15.0 8.1 68.4 9.7 6.5 6.0 42.3 8.6 7.3 4.6 6.1 9.1 5.6 16.9 7.2 9.0 9.5 7.8 8.2 15.1 16.5 15.5 9.4 9.6 7.9 6.4 7.1 5.6 10.9 10.6 4.7 12.8 6.0 10.8 8.5 14.1 7.2 8.8 4.0 7.9 5.7 30.9 15.5 4.7 8.8 12.9 14.0 8.7 18.2 8.8 13.1 17.1 8.8 15.4 9.7 13.6 5.4 5.6 2.5 8.5 15.7 6.0 8.0 5.2 11.4 57.1 5.8 6.0 16.6 12.9 9.2 6.4 18.7 4.1 10.8 12.6 12.7 7.5 7.2 10.1 16.9 8.3 8.0 8.8 11.5 18.3 1.2 9.4 2.5 2.3 1.3 1.4 1.3 1.8 1.7 1.5 2.1 2.1 0.1 0.5 1.4 0.9 1.6 1.3 5.0 7.3 7.1 6.7 5.1 6.3 7.6 7.3 7.8 6.5 7.3 9.0 8.0 16.0 6.7 8.1 4.9 3.7 6.2 8.9 5.2 6.6 15.0 7.9 5.2 10.0 11.3 7.3 4.2 8.2 4.3 209.3 25.4 6.9 19.5 10.0 13.6 7.0 16.2 36.6 5.9 12.9 6.7 7.9 23.0 25.8 1.3 9.6 9.7 134.8 6.2 10.1 8.2 77.1 14.2 9.7 1.9 12.7 2.8 5.2 5.4 11.2 5.4 4.9 8.2 2.0 11.3 9.1 58.4 5.7 3.6 28.5 87.0 63.1 6.4 12.2 13.1 6.0 5.9 27.2 19.1 8.5 3.4 3.3 4.9 10.3 60.9 39.0 ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6" O75354 20 25195693-25228075 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 289.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 41000 "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA015491: AB_2669200, HPA069555: AB_2686152" "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" 24.8 55.4 54.3 22.8 64.0 15.2 27.7 39.7 65.9 22.9 26.5 61.0 60.0 21.8 18.4 25.3 23.2 26.5 75.9 56.0 49.8 40.4 38.9 25.4 16.1 29.6 32.2 36.2 49.6 23.5 60.0 25.2 45.2 55.7 44.9 15.7 71.2 17.2 38.7 19.4 63.0 18.6 25.7 19.8 47.2 36.3 48.5 29.8 28.8 21.9 13.0 24.5 21.8 38.9 78.8 122.8 32.9 64.0 41.0 50.8 70.8 63.0 45.0 54.0 48.3 65.5 60.0 47.6 91.4 60.9 104.7 100.3 40.1 96.2 35.5 29.2 36.2 38.3 18.2 150.4 60.7 52.7 57.3 47.4 53.1 67.7 51.4 39.4 43.7 46.1 51.5 78.8 40.0 75.6 49.2 32.6 20.8 63.9 96.0 27.1 102.9 108.4 67.8 46.3 52.0 26.7 17.7 105.1 289.4 29.6 75.3 43.4 48.6 61.9 63.7 51.6 75.7 50.5 43.8 21.0 44.5 34.1 116.3 0.1 25.2 4.9 18.8 17.0 25.6 8.7 16.5 15.0 26.4 11.0 16.9 15.5 1.1 14.1 7.6 18.5 17.2 22.1 54.3 64.0 39.7 65.9 56.0 49.8 29.6 32.2 45.2 25.7 48.5 38.9 6.4 19.2 28.5 12.4 9.9 9.8 16.2 23.6 6.2 19.2 25.8 21.8 5.8 25.8 14.8 18.4 10.4 63.2 11.0 81.4 9.8 42.5 22.1 10.5 7.6 7.6 34.0 4.2 18.6 40.1 21.7 12.8 52.5 15.4 3.8 65.2 14.3 15.0 26.7 25.2 19.4 57.5 26.4 17.7 17.4 65.2 20.5 17.6 10.6 11.2 16.0 4.2 10.3 13.0 9.2 33.8 59.8 42.2 16.5 27.9 68.4 13.5 10.7 9.1 6.6 6.3 9.6 3.0 8.8 8.6 6.0 59.8 12.0 25.8 72.6 12.1 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 27.6;liver: 14.5" "Group enriched" "Detected in some" 5 "Distal enterocytes: 194.5;Intestinal goblet cells: 181.0;Paneth cells: 174.3;Proximal enterocytes: 167.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.0;OE19: 1.7;RPMI-8226: 5.3;T-47d: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favorable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 1.4 0.0 0.4 0.4 0.2 0.2 0.6 0.0 21.3 27.6 0.1 0.0 0.3 0.7 3.7 0.0 0.0 0.0 3.1 14.5 0.1 0.1 0.2 0.1 0.1 3.1 0.1 5.1 0.1 0.0 0.4 11.2 0.0 6.3 0.2 0.0 0.1 27.2 0.1 0.0 0.2 8.9 0.5 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 5.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 1.7 0.2 0.0 0.0 5.3 0.7 0.0 0.2 0.5 0.1 0.0 0.1 0.4 2.8 0.1 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 1.7 1.5 0.4 11.5 0.3 20.2 0.0 0.0 0.1 194.5 0.0 1.3 0.0 3.0 0.4 0.1 3.6 0.0 0.0 7.5 0.2 0.1 31.6 4.7 0.0 0.1 0.4 10.1 0.1 0.0 0.0 181.0 8.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 174.3 0.0 0.2 0.6 167.3 5.9 1.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.3 0.1 15.6 1.7 EPB41L4B "EHM2, LULU2" ENSG00000095203 "Erythrocyte membrane protein band 4.1 like 4B" Q9H329 9 109171974-109321059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.9;pancreas: 149.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 134.8;Excitatory neurons: 79.7;Hepatocytes: 125.2;Proximal enterocytes: 79.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 31.7;hTCEpi: 49.8;OE19: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042862 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA042862: AB_10794534" "prognostic unfavorable (1.02e-4)" "unprognostic (6.58e-2)" "unprognostic (2.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" "unprognostic (6.19e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (3.60e-1)" "unprognostic (6.20e-2)" "unprognostic (8.82e-4)" "unprognostic (1.46e-3)" "unprognostic (1.43e-1)" "unprognostic (4.65e-2)" "unprognostic (1.29e-1)" 21.0 9.7 6.0 4.5 8.7 0.0 15.3 2.0 12.2 4.1 11.8 57.6 47.6 1.2 17.9 1.5 10.8 4.2 8.8 10.7 6.4 6.4 88.9 6.3 0.2 2.7 5.3 13.8 149.1 11.1 1.6 2.5 3.7 7.6 56.7 3.0 26.9 9.1 6.1 15.5 51.9 1.9 7.2 0.1 30.6 7.5 10.9 0.6 44.7 0.7 1.6 2.2 3.4 4.3 8.7 10.8 0.7 0.8 0.8 0.0 31.7 1.1 0.4 3.7 1.9 18.5 8.5 0.0 2.3 1.0 8.9 13.9 21.5 11.5 3.9 9.2 5.1 0.0 3.4 26.5 2.2 0.4 0.0 0.3 49.8 1.5 17.0 1.1 0.2 8.0 0.3 0.0 5.2 22.3 0.4 0.2 13.8 62.8 15.7 0.0 0.0 0.6 12.9 13.1 13.1 1.4 3.4 22.2 0.0 6.3 5.2 0.1 0.5 7.5 7.6 2.5 3.1 0.1 0.1 0.0 5.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 8.7 2.0 12.2 10.7 6.4 2.7 5.3 3.7 7.2 10.9 4.3 0.2 6.4 5.1 2.6 0.4 11.5 5.4 6.0 1.2 7.5 22.7 10.4 18.5 20.0 9.6 7.3 0.0 4.1 0.0 134.8 0.0 3.5 11.7 23.8 2.3 0.8 51.6 0.0 79.7 20.8 2.1 2.5 26.0 20.7 0.0 6.2 5.0 125.2 0.6 38.7 58.9 51.4 12.2 1.6 1.5 1.9 13.4 0.4 1.8 3.7 0.0 1.9 0.0 12.1 3.8 10.2 54.4 2.6 0.0 7.2 79.2 0.8 39.2 1.1 0.0 0.8 1.0 1.4 17.2 0.9 24.0 1.9 0.5 6.8 46.5 6.5 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561785-184582408 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 38.1;Breast myoepithelial cells: 50.8;Enteroendocrine cells: 71.5;Intestinal goblet cells: 43.3;Squamous epithelial cells: 44.3;Undifferentiated cells: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 28.8;HaCaT: 40.2;OE19: 28.3;SK-BR-3: 30.9;T-47d: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.7 0.7 3.0 3.7 2.7 0.1 10.4 5.8 4.1 22.7 1.0 10.3 6.4 10.1 1.8 30.6 4.0 2.8 1.9 2.9 2.4 5.8 0.9 3.4 0.9 5.7 3.4 8.3 14.9 1.1 2.0 5.7 6.1 10.0 10.9 0.5 31.7 3.5 0.5 51.5 6.3 3.8 2.3 1.0 22.8 0.9 4.0 0.7 0.9 0.4 2.4 4.0 20.9 2.7 6.6 2.3 14.8 1.6 4.5 0.3 28.8 1.1 1.9 2.2 1.2 2.0 0.2 0.0 2.8 6.3 1.0 40.2 5.4 1.9 0.6 0.2 1.1 0.0 0.3 0.0 0.3 0.0 0.2 1.2 13.0 1.8 0.2 0.7 0.0 0.0 0.0 0.0 1.0 17.6 0.0 6.4 1.4 28.3 2.5 1.5 9.0 0.0 0.0 5.8 1.9 2.2 1.2 30.9 1.3 7.8 20.5 0.1 0.0 3.6 5.1 1.8 2.5 0.0 0.0 0.1 0.3 0.0 14.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 5.8 4.1 2.9 2.4 5.7 3.4 6.1 2.3 4.0 2.7 0.9 3.2 2.7 11.1 0.2 24.1 7.6 5.3 17.1 0.9 38.1 50.8 1.8 2.8 4.6 0.0 0.0 10.1 1.1 21.5 1.9 0.5 0.6 3.7 4.0 1.4 71.5 0.0 4.6 1.6 18.7 6.9 27.0 7.5 4.5 2.1 1.8 0.0 23.5 15.2 5.8 43.3 10.2 0.3 9.8 0.4 2.8 2.4 0.0 1.0 0.8 0.1 0.0 5.0 0.3 3.2 7.2 6.0 0.0 6.0 1.7 0.2 1.4 1.0 0.0 4.5 2.9 0.4 0.6 44.3 35.8 16.3 0.8 1.6 55.0 20.7 EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620134-15882329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 317.0;Sertoli cells: 401.0;Smooth muscle cells: 313.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 22.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 253.0;HHSteC: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003897 Approved Approved "Golgi apparatus" NA NA 17000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA003897: AB_1848224" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-2)" "unprognostic (5.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (3.33e-7)" "unprognostic (2.68e-1)" "prognostic favorable (1.45e-7)" "unprognostic (7.47e-3)" "unprognostic (7.20e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.79e-2)" 62.3 13.0 12.9 16.1 17.4 0.6 33.7 15.3 14.0 53.9 14.1 49.7 37.6 46.2 47.1 20.5 20.1 56.0 26.4 11.1 17.2 55.8 37.8 29.0 9.4 18.5 20.1 49.2 15.1 21.6 3.5 53.1 19.7 16.4 53.7 39.8 13.4 39.8 13.8 11.9 42.7 53.7 15.5 11.9 32.0 15.6 16.1 4.8 22.8 24.3 5.2 51.7 21.4 20.8 65.0 38.8 37.7 1.4 253.0 177.6 53.1 73.6 59.8 34.5 46.1 33.3 97.3 0.0 2.4 140.4 114.4 16.4 11.3 9.5 52.4 0.2 12.6 5.7 11.2 34.7 218.1 4.4 0.2 159.8 42.8 91.7 115.7 44.6 17.7 0.2 0.1 0.2 169.0 17.5 0.2 2.8 5.2 50.3 30.8 0.0 109.5 0.8 97.7 92.5 3.1 4.9 21.4 12.4 91.5 6.2 34.2 4.3 28.7 54.7 14.3 32.4 30.7 3.6 0.4 0.1 32.1 10.7 160.0 0.0 2.7 0.2 0.2 10.8 0.1 1.3 0.9 0.4 5.5 0.3 1.1 0.5 4.4 1.0 22.2 0.4 0.1 1.7 12.9 17.4 15.3 14.0 11.1 17.2 18.5 20.1 19.7 15.5 16.1 20.8 121.4 12.8 175.9 91.1 11.6 17.0 39.6 32.0 13.6 9.7 28.7 42.8 27.6 87.2 58.3 23.9 66.7 33.0 15.2 317.0 60.7 69.4 67.6 87.4 72.0 61.4 38.3 0.4 2.2 68.9 7.3 73.4 81.1 152.2 6.3 139.4 36.0 36.0 65.8 6.7 31.1 54.5 67.1 54.1 35.6 49.4 134.8 46.2 35.6 148.0 8.6 15.4 0.0 121.2 96.9 97.0 217.8 43.6 5.2 26.9 69.0 114.6 104.8 153.7 401.0 18.1 313.1 10.9 4.2 22.8 13.1 21.1 11.8 40.0 80.0 97.6 EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 188.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 211.4;Paneth cells: 175.3;Proximal enterocytes: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 234.3;BEWO: 220.8;CAPAN-2: 206.6;SK-BR-3: 257.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 9.2" HPA041143 Approved Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041143: AB_10794985" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.87e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (3.25e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-1)" "unprognostic (2.79e-1)" "unprognostic (5.03e-2)" 7.8 11.2 5.2 5.7 4.8 0.0 27.0 8.9 5.5 49.4 4.9 42.7 100.8 11.4 3.5 188.5 19.2 13.3 4.3 4.5 6.8 98.4 101.7 32.4 0.7 10.9 9.2 11.8 43.7 3.8 11.5 17.7 6.2 29.3 15.5 1.0 94.6 15.2 1.3 76.3 105.0 2.9 7.1 1.4 48.1 3.2 7.1 2.0 70.2 0.4 10.9 17.5 80.1 6.5 234.3 68.6 0.2 1.6 2.7 14.4 220.8 20.1 20.3 29.2 12.5 51.4 206.6 0.4 81.6 21.4 5.4 122.4 0.6 117.8 6.4 0.6 5.4 0.0 27.7 94.7 16.3 0.3 0.4 8.1 77.8 8.0 18.7 12.3 0.2 0.1 1.8 1.1 3.2 72.1 0.5 1.3 2.7 71.5 24.0 0.5 0.8 1.8 103.8 55.2 0.8 0.8 75.9 257.5 0.5 14.3 94.9 0.2 1.5 11.2 27.3 7.2 1.6 0.9 1.0 0.8 6.1 0.6 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.1 5.2 4.8 8.9 5.5 4.5 6.8 10.9 9.2 6.2 7.1 7.1 6.5 1.8 141.1 51.8 3.9 11.2 19.8 26.2 48.8 51.8 0.6 39.1 37.0 4.5 57.2 62.4 90.1 0.0 47.9 21.6 211.4 27.4 55.2 1.0 47.3 7.1 4.7 43.8 1.3 3.1 80.0 33.4 11.5 131.0 60.8 7.0 0.4 0.7 59.4 4.7 0.0 3.8 76.8 32.6 2.1 7.8 2.3 18.0 2.7 14.2 2.8 3.1 10.0 16.5 2.0 0.7 83.2 175.3 11.7 7.6 33.6 235.9 108.2 60.9 1.5 0.0 0.9 7.5 1.1 4.8 74.9 24.4 92.5 18.6 0.9 77.2 32.1 EPS8L3 "FLJ21522, MGC16817" ENSG00000198758 "EPS8 like 3" Q8TE67 1 109750080-109764027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 35.7;intestine: 142.1;stomach 1: 50.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 254.4;Gastric mucus-secreting cells: 80.5;Intestinal goblet cells: 103.4;Late spermatids: 144.6;Paneth cells: 257.8;Proximal enterocytes: 285.3;Undifferentiated cells: 112.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 52.5;pancreatic cancer: 29.7;stomach cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 15.6;CAPAN-2: 14.4;Hep G2: 36.2;OE19: 67.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030998 Approved Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA030998: AB_2673691" "unprognostic (1.73e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.13e-5)" "unprognostic (5.55e-3)" "unprognostic (3.71e-2)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.87e-3)" "unprognostic (3.89e-1)" "prognostic favorable (1.82e-4)" 0.0 0.0 0.1 10.8 0.0 0.0 0.2 0.0 0.0 1.3 0.0 77.1 141.8 0.2 0.9 0.1 0.1 35.7 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 77.1 0.0 0.0 0.2 0.0 0.0 142.1 2.9 0.0 0.0 50.7 2.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.6 14.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 67.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 14.3 0.3 0.0 0.0 0.0 0.0 254.4 0.0 11.6 28.0 0.7 0.1 0.3 51.4 0.0 0.0 23.9 0.0 0.0 80.5 1.0 4.5 0.0 0.0 0.2 0.0 0.0 0.0 103.4 0.0 0.0 0.0 144.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.5 257.8 0.4 0.3 0.0 285.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.4 0.6 112.6 1.8 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 136.1;Distal enterocytes: 111.0;Proximal enterocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 5.0" "Lineage enriched" "Detected in many" 4 "T-cells: 5.0" "Group enriched" "Detected in many" 41 "OE19: 6565.0;SK-BR-3: 3115.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 980000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavorable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favorable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 13.0 5.4 16.1 12.1 20.5 1.6 56.0 14.3 13.1 37.6 23.3 68.2 63.6 25.2 26.6 102.4 64.2 31.0 57.0 13.3 16.0 73.5 31.1 36.2 4.8 22.4 22.7 23.9 37.6 81.7 17.3 27.0 17.1 55.6 48.5 8.1 68.7 50.5 20.7 91.0 67.3 25.0 18.5 6.9 49.7 11.7 15.4 7.4 56.5 15.0 28.0 40.0 52.9 16.4 38.7 45.7 50.4 31.7 59.3 41.2 67.7 27.2 44.9 58.6 48.9 34.4 102.7 2.9 54.6 62.7 31.5 117.6 2.8 61.2 26.9 5.2 38.6 1.8 36.0 56.3 35.3 0.9 1.0 41.0 56.6 36.2 21.9 56.2 24.4 1.9 6.2 2.4 43.3 59.4 7.1 3.0 90.7 6565.0 11.7 3.9 20.5 5.4 58.9 118.9 9.4 2.6 51.5 3115.9 16.9 62.2 88.1 2.2 2.9 30.2 37.7 37.7 17.6 5.3 3.3 3.6 3.0 0.9 98.5 1.1 0.2 0.4 5.0 0.1 0.3 0.6 0.2 1.4 0.2 0.6 0.5 1.4 1.2 0.4 0.1 0.1 0.2 1.7 16.1 20.5 14.3 13.1 13.3 16.0 22.4 22.7 17.1 18.5 15.4 16.4 3.9 41.7 40.1 12.7 2.2 14.0 19.0 37.1 17.6 4.6 62.7 34.9 20.7 32.9 43.8 136.1 12.5 12.0 5.1 111.0 7.9 30.9 0.3 48.7 13.9 6.1 15.6 1.3 0.9 25.5 84.8 15.7 53.5 61.3 0.0 20.3 11.7 10.7 4.0 6.7 1.0 47.5 42.7 2.2 3.1 1.0 18.3 1.7 10.6 1.0 1.2 24.1 26.8 2.0 1.0 32.5 54.8 23.0 1.1 34.9 121.7 19.5 42.0 5.8 0.0 13.1 12.7 6.8 5.7 43.5 18.9 22.7 2.8 4.4 75.4 31.3 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ETHE1 "HSCO, YF13H12" ENSG00000105755 "ETHE1 persulfide dioxygenase" O95571 19 43506719-43527230 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 256.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1037.7;Paneth cells: 788.4;Proximal enterocytes: 376.3;Undifferentiated cells: 447.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 222.6;OE19: 360.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028360, HPA029028, HPA029029" Enhanced Enhanced Mitochondria No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA028360: AB_10599297, HPA029028: AB_10602092, HPA029029: AB_10601998" "unprognostic (8.04e-2)" "unprognostic (3.33e-1)" "unprognostic (1.50e-2)" "unprognostic (2.45e-1)" "unprognostic (8.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.58e-4)" "unprognostic (7.75e-2)" "unprognostic (2.28e-1)" "unprognostic (5.47e-2)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.27e-2)" "unprognostic (1.75e-1)" "unprognostic (9.72e-3)" "unprognostic (2.73e-2)" 24.4 27.9 16.1 34.8 17.0 45.8 26.7 16.5 17.3 28.7 15.8 256.1 85.5 18.3 29.8 81.0 20.6 21.0 18.8 15.6 17.4 40.4 52.7 30.5 23.4 17.3 17.2 13.5 28.9 16.1 19.1 26.3 16.6 27.1 226.6 3.2 40.1 18.5 22.8 27.2 77.0 35.6 17.1 27.8 37.8 3.0 18.2 19.8 24.1 21.9 41.7 34.4 39.1 17.2 54.1 68.9 14.1 49.6 75.1 50.9 5.5 82.1 222.6 69.8 71.1 21.1 54.3 0.2 60.0 79.8 22.2 42.9 20.6 123.4 19.6 26.2 6.2 13.8 29.7 59.2 34.0 19.3 18.4 52.2 95.1 26.9 76.0 92.2 52.0 49.8 9.0 87.6 35.1 35.7 22.2 18.9 3.8 360.5 32.9 26.6 6.1 12.0 153.0 110.9 0.2 16.6 20.8 74.8 50.6 23.6 22.4 34.3 41.6 10.9 46.9 13.1 15.3 23.1 20.2 1.4 48.4 83.8 57.7 24.2 63.3 1.6 41.1 34.5 48.3 20.5 47.6 39.4 95.8 7.5 36.4 35.0 2.1 29.3 22.8 17.9 50.4 40.2 16.1 17.0 16.5 17.3 15.6 17.4 17.3 17.2 16.6 17.1 18.2 17.2 32.0 22.4 23.4 3.9 25.5 34.5 82.2 242.5 57.5 9.8 85.8 95.2 9.8 47.1 84.5 55.2 0.0 191.6 38.0 1037.7 54.8 71.7 0.9 31.0 41.2 44.9 63.7 17.4 6.2 63.6 95.7 42.1 53.5 68.2 38.0 12.6 42.1 89.2 115.1 5.0 6.8 324.2 79.3 105.0 78.5 2.1 17.7 74.6 80.0 3.7 78.5 11.7 63.8 4.0 5.6 102.7 788.4 16.1 34.9 75.0 376.3 136.4 23.1 5.8 19.7 32.0 45.1 2.1 6.2 82.8 23.2 92.5 50.4 15.8 447.5 146.5 EXD3 "FLJ20433, LOC54932, mut-7, Nbr" ENSG00000187609 "Exonuclease 3'-5' domain containing 3" Q8N9H8 9 137306896-137423211 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 73.2;Paneth cells: 178.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.4" "Low region specificity" "Detected in all" HPA047395 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Focal adhesion sites" "Actin filaments" "HPA047395: AB_10962864" "unprognostic (2.91e-1)" "unprognostic (5.67e-2)" "unprognostic (1.75e-3)" "prognostic favorable (4.30e-4)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (1.37e-1)" "unprognostic (2.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-3)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "unprognostic (7.99e-3)" "unprognostic (2.05e-1)" "unprognostic (8.67e-2)" "unprognostic (5.05e-2)" 9.4 10.1 6.2 3.5 6.8 3.5 10.8 5.9 11.0 11.5 6.6 16.0 9.4 9.9 1.5 11.6 12.3 4.2 11.2 6.5 5.8 12.2 8.1 10.2 3.8 7.2 6.1 10.7 9.8 3.7 13.5 3.4 6.4 14.5 3.6 0.8 10.1 3.7 9.5 10.2 11.3 1.4 5.5 14.8 12.3 4.8 6.1 1.1 11.4 2.6 2.3 10.9 11.2 6.3 8.3 7.0 3.3 9.5 2.8 4.0 7.8 4.0 4.5 3.5 5.3 4.8 17.5 3.5 9.1 3.1 8.7 14.5 1.0 4.4 1.1 8.2 8.1 2.6 13.0 7.9 8.5 1.9 29.4 4.8 6.0 3.1 2.8 10.2 11.9 0.0 7.0 6.4 3.0 22.3 0.1 6.9 3.8 18.1 4.7 6.3 2.6 25.3 7.1 4.7 4.5 7.7 4.0 8.4 3.8 3.8 13.6 9.3 15.0 4.8 4.4 7.5 6.2 8.1 4.1 3.0 8.7 6.4 7.4 10.7 3.4 7.8 2.2 4.5 2.7 2.6 4.0 2.1 3.9 2.4 3.1 2.5 0.8 4.1 4.4 2.5 6.1 2.3 6.2 6.8 5.9 11.0 6.5 5.8 7.2 6.1 6.4 5.5 6.1 6.3 17.6 0.0 6.3 24.2 5.3 5.9 10.0 8.9 13.6 14.6 13.5 17.0 5.2 10.0 11.2 7.3 14.6 9.9 8.1 46.4 9.8 6.8 17.9 11.5 6.5 14.1 7.3 5.0 21.6 11.3 3.3 7.3 19.4 13.1 61.7 10.5 17.2 7.2 9.2 21.9 24.1 27.6 16.2 5.4 7.3 73.2 5.9 6.9 3.6 13.1 6.2 10.0 12.3 26.2 14.6 6.4 178.2 7.9 6.6 10.0 31.3 11.9 9.3 10.4 13.1 5.5 9.9 2.3 8.9 9.9 8.9 4.0 6.4 19.5 39.0 9.2 F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.4;stomach 1: 44.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.9;Distal enterocytes: 124.7;Gastric mucus-secreting cells: 74.5;Glandular and luminal cells: 74.7;Paneth cells: 86.1;Suprabasal keratinocytes: 168.4;Urothelial cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 42.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.0" "Cell line enhanced" "Detected in many" "PC-3: 126.0;RPTEC TERT1: 205.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" 1.0 1.3 0.8 6.2 0.9 1.7 8.0 0.5 0.8 3.6 8.9 59.4 45.8 2.9 4.8 8.2 8.2 29.9 4.6 0.5 0.8 31.8 7.1 4.1 1.4 1.7 2.2 0.5 23.6 5.2 1.5 3.9 1.4 5.0 53.0 2.6 8.9 11.5 0.3 37.5 41.0 2.7 1.0 3.8 44.0 0.6 0.9 1.1 8.3 0.2 1.6 27.5 5.8 0.8 32.7 52.1 4.3 0.2 1.5 4.0 33.1 1.6 17.1 0.9 2.7 45.0 81.8 0.0 69.5 3.7 78.1 54.4 27.1 24.0 1.5 0.1 26.8 0.8 1.0 32.8 10.6 0.0 0.3 5.5 67.3 8.0 49.8 8.0 84.9 7.8 0.4 0.0 0.1 17.6 3.8 0.1 5.7 17.9 126.0 0.1 0.0 0.8 205.9 58.5 2.1 0.4 12.3 12.6 0.3 48.5 5.3 0.3 57.1 0.1 31.8 0.1 0.3 4.8 1.0 0.1 18.7 0.0 1.4 11.9 10.0 1.8 0.4 3.2 2.1 0.5 3.8 1.9 4.7 0.1 3.4 2.1 42.0 0.7 0.5 0.5 1.0 4.0 0.8 0.9 0.5 0.8 0.5 0.8 1.7 2.2 1.4 1.0 0.9 0.8 0.3 9.6 3.7 0.0 0.9 109.9 17.8 4.5 10.8 0.5 10.5 6.3 0.3 32.9 12.7 31.3 0.0 5.4 0.2 124.7 1.9 28.0 0.0 40.9 5.1 1.2 13.1 2.5 0.2 15.0 7.9 2.9 74.5 74.7 2.5 1.0 1.1 9.6 0.9 0.0 1.4 50.8 4.1 1.9 3.8 0.0 0.0 2.1 1.8 1.0 2.6 0.0 0.0 0.0 0.0 44.7 86.1 0.0 0.1 34.1 62.9 19.3 25.0 2.0 0.0 0.4 2.8 0.9 1.3 37.0 168.4 2.1 2.1 0.1 50.7 116.0 FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394317-46413848 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 128.5;Proximal enterocytes: 87.4;Spermatocytes: 89.0" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 29.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 37.5;OE19: 18.8;RT4: 42.4;SK-BR-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favorable (4.25e-5)" "prognostic favorable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" 7.5 14.2 23.5 2.9 28.4 10.4 9.5 25.6 29.6 7.5 29.3 18.9 22.0 3.9 9.1 8.7 12.0 5.2 5.0 24.6 23.3 20.0 32.8 7.8 2.5 32.1 25.4 3.9 22.4 24.6 19.0 3.4 28.7 44.1 15.2 5.5 17.4 7.1 9.5 12.1 22.0 2.3 27.9 3.3 17.1 46.8 26.4 7.1 38.6 5.6 2.7 6.9 8.2 45.8 5.0 1.2 0.8 1.0 1.2 0.8 37.5 1.0 0.5 0.5 0.8 7.3 11.4 0.3 3.9 0.7 0.4 16.2 0.7 2.3 0.2 2.2 5.4 0.1 0.2 3.5 0.8 1.4 2.8 0.6 10.7 0.4 1.3 0.4 0.0 0.9 0.1 0.8 0.0 10.7 0.8 2.2 3.2 18.8 0.4 0.9 0.4 0.2 9.0 42.4 4.8 3.6 5.6 21.2 0.2 0.9 14.6 14.5 0.0 0.1 0.6 1.1 0.7 2.1 1.0 0.6 0.1 13.4 0.4 0.0 6.9 29.1 0.4 1.9 0.2 0.1 0.4 0.2 8.2 0.1 0.6 0.6 0.4 0.5 1.0 8.8 0.2 1.4 23.5 28.4 25.6 29.6 24.6 23.3 32.1 25.4 28.7 27.9 26.4 45.8 1.2 22.4 13.2 6.5 2.4 5.2 29.0 6.8 10.2 15.5 15.4 9.0 2.9 27.1 11.0 22.0 43.8 16.3 7.3 51.6 0.0 12.4 50.7 9.5 1.9 1.8 15.5 6.6 15.7 6.4 8.7 3.7 37.8 6.0 0.0 6.3 0.4 37.1 2.8 1.7 11.4 38.2 10.2 2.5 4.2 128.5 7.5 3.3 5.4 1.9 2.5 7.3 0.0 7.5 45.1 4.2 41.3 4.5 0.7 20.1 87.4 22.6 5.2 14.5 0.0 2.9 3.2 89.0 23.0 6.4 6.0 12.4 1.2 1.3 55.2 18.9 FAM120A "C9orf10, KIAA0183, OSSA" ENSG00000048828 "Family with sequence similarity 120A" Q9NZB2 9 93451685-93566112 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019734, HPA055800" Approved Enhanced Cytosol NA NA 12000 "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA019734: AB_1848369, HPA055800: AB_2682925" "unprognostic (5.92e-2)" "unprognostic (2.15e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.03e-4)" "unprognostic (3.36e-1)" "unprognostic (2.33e-2)" "unprognostic (8.93e-2)" "unprognostic (5.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.27e-2)" "unprognostic (3.71e-3)" "prognostic favorable (1.08e-7)" "unprognostic (8.16e-2)" "unprognostic (1.60e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" 48.1 47.8 26.7 59.7 30.8 49.9 37.8 25.8 27.0 45.0 55.0 74.4 59.0 39.2 36.0 46.6 50.8 42.3 60.9 26.0 24.2 47.7 55.7 42.0 56.5 32.6 29.3 39.1 57.9 87.3 26.8 60.3 28.8 42.7 69.1 30.6 56.2 40.8 81.7 41.9 58.4 50.9 25.3 49.0 69.3 17.4 30.3 45.5 49.0 71.4 45.6 53.4 33.0 28.7 179.7 145.4 32.0 92.8 93.7 116.6 100.3 123.2 107.8 92.9 68.0 47.5 108.2 116.1 68.9 156.2 73.7 188.8 86.5 144.3 71.1 117.0 62.8 63.8 126.1 75.3 104.6 109.0 83.5 114.3 87.2 105.7 166.3 90.9 133.7 81.0 74.4 94.9 101.3 202.8 108.2 61.4 41.2 212.7 134.3 62.1 85.6 97.4 112.3 107.2 85.8 52.5 139.5 166.4 86.0 31.4 91.0 70.6 140.6 99.6 71.6 123.8 136.4 74.2 78.6 44.8 107.9 96.6 90.9 3.1 6.6 5.2 4.9 7.5 4.1 4.4 4.3 4.8 6.1 3.5 3.0 4.4 13.1 4.3 9.3 3.9 8.3 4.1 26.7 30.8 25.8 27.0 26.0 24.2 32.6 29.3 28.8 25.3 30.3 28.7 64.0 44.8 93.9 67.9 42.7 102.2 49.6 56.6 70.6 30.0 86.5 49.0 112.3 77.2 75.2 75.4 50.1 73.8 49.2 164.3 21.5 50.1 26.1 77.5 76.2 64.9 91.8 60.2 92.1 74.7 104.9 60.5 123.8 92.3 48.8 66.1 63.1 186.6 71.0 40.4 62.5 176.8 36.7 146.4 78.6 9.8 66.8 103.4 53.4 80.6 111.0 35.7 35.0 64.3 80.9 86.4 92.0 65.5 60.8 125.8 81.0 75.7 87.8 33.7 39.5 63.5 68.6 12.3 12.4 91.1 114.2 103.4 49.3 94.4 177.2 109.0 FAM160A2 "C11orf56, DKFZP566M1046, FHIP, FLJ22665, KIAA1759" ENSG00000051009 "Family with sequence similarity 160 member A2" Q8N612 11 6211345-6234711 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055994, HPA063987" Approved Approved Mitochondria NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA055994: AB_2682999, HPA063987: AB_2685166" "unprognostic (1.40e-1)" "unprognostic (1.58e-1)" "unprognostic (3.44e-2)" "unprognostic (9.59e-3)" "unprognostic (2.20e-2)" "unprognostic (1.51e-1)" "unprognostic (4.16e-2)" "unprognostic (2.64e-1)" "unprognostic (2.19e-1)" "unprognostic (5.02e-2)" "unprognostic (2.16e-1)" "unprognostic (8.04e-2)" "unprognostic (6.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.64e-1)" "unprognostic (9.58e-2)" "unprognostic (1.85e-1)" 16.5 14.5 6.2 14.2 6.5 42.3 18.1 6.8 7.2 20.1 9.5 29.8 34.1 21.6 9.5 13.2 20.2 17.8 12.4 6.4 3.8 13.8 20.8 16.0 13.3 4.0 4.4 21.3 24.7 16.3 14.9 12.1 3.5 15.7 27.7 9.6 18.6 14.7 14.0 23.5 33.8 15.8 2.9 14.2 18.9 27.2 4.4 11.3 22.7 10.5 8.9 16.5 16.5 4.4 13.5 13.1 9.0 13.4 11.9 12.8 19.5 7.6 9.1 11.1 10.6 11.2 24.4 10.5 8.2 8.9 18.3 17.4 9.2 13.8 6.7 11.6 13.1 3.6 24.1 6.0 9.8 8.9 11.6 11.7 17.0 10.0 17.7 14.5 11.4 16.2 11.5 12.7 7.0 10.7 8.5 17.0 13.4 17.5 12.2 9.3 4.7 8.6 10.4 9.6 12.0 7.9 10.9 12.7 6.9 9.3 8.7 12.4 9.8 13.6 10.4 20.4 8.1 17.0 15.7 8.1 15.0 7.0 12.3 1.3 3.1 3.4 3.0 1.3 1.8 1.3 1.2 2.2 2.0 1.3 0.9 1.6 3.3 1.1 1.0 0.6 0.2 2.0 6.2 6.5 6.8 7.2 6.4 3.8 4.0 4.4 3.5 2.9 4.4 4.4 19.0 19.2 16.2 28.1 10.1 12.5 11.1 12.5 10.8 12.6 17.8 12.3 4.5 14.3 12.2 12.9 16.7 13.5 15.9 76.8 7.9 11.4 24.2 15.6 10.1 15.2 25.0 18.5 21.3 11.3 10.1 12.9 33.6 11.2 7.0 27.6 9.3 23.7 9.6 6.7 15.8 37.9 16.2 17.6 28.5 6.5 9.9 12.3 14.2 11.2 16.9 7.6 37.0 14.1 15.6 17.6 47.8 7.5 8.3 10.8 65.0 8.8 18.6 24.4 13.1 10.6 11.6 38.5 21.7 8.5 14.9 11.5 14.7 21.9 39.5 10.4 FAM168B "KIAA0280L, MANI" ENSG00000152102 "Family with sequence similarity 168 member B" A1KXE4 2 131047876-131093460 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043778, HPA061659" Enhanced NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA043778: AB_10964889, HPA061659: AB_2684577" "unprognostic (8.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.61e-1)" "unprognostic (3.26e-2)" "unprognostic (4.58e-2)" "unprognostic (6.90e-3)" "unprognostic (1.60e-2)" "unprognostic (2.10e-1)" "unprognostic (5.91e-2)" "unprognostic (1.88e-1)" "unprognostic (4.84e-2)" "unprognostic (1.88e-1)" "prognostic favorable (5.30e-5)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (3.35e-3)" 41.5 33.7 55.5 26.8 67.7 46.2 32.1 49.8 60.1 35.4 32.6 54.2 26.3 51.4 26.5 34.4 37.9 23.7 43.4 57.5 52.1 38.4 30.9 27.6 27.8 51.4 53.6 46.9 30.1 46.7 20.3 29.4 54.0 37.5 31.9 48.6 28.1 46.8 69.9 29.9 34.3 40.8 54.7 24.2 36.3 26.8 60.1 38.5 36.2 52.9 31.3 47.6 28.0 55.8 74.1 47.6 98.2 67.7 82.2 62.4 74.0 75.2 54.9 46.3 39.7 88.1 40.0 78.6 61.1 79.8 31.8 57.1 83.8 83.8 66.2 64.8 62.3 72.1 49.8 67.4 83.0 84.8 58.6 63.6 82.4 94.5 81.0 62.3 65.5 72.3 70.3 28.9 72.2 53.4 68.0 55.3 61.6 60.2 57.5 85.0 82.5 70.2 63.7 84.0 71.3 100.0 58.2 58.8 80.1 46.0 52.4 79.2 70.8 77.3 78.9 58.0 73.9 67.9 81.2 98.1 65.9 49.3 70.7 2.5 2.2 4.3 4.4 1.5 4.0 3.0 3.6 3.7 2.0 3.0 4.7 3.4 2.1 2.5 3.4 3.3 3.2 2.8 55.5 67.7 49.8 60.1 57.5 52.1 51.4 53.6 54.0 54.7 60.1 55.8 24.4 35.3 27.4 25.1 19.0 22.8 18.3 24.5 16.5 32.2 28.6 23.6 51.4 24.3 21.6 35.0 37.5 27.0 22.5 38.8 5.9 24.8 12.3 28.0 21.6 22.8 31.8 13.3 47.9 30.8 24.8 23.8 19.4 29.0 19.0 34.7 22.1 39.8 20.1 30.3 52.2 29.8 14.2 25.1 16.0 11.1 29.2 19.2 24.9 28.1 20.9 27.0 14.4 18.6 38.8 38.0 25.3 49.7 25.1 33.3 27.3 26.8 19.5 42.3 13.1 27.5 27.4 18.2 22.8 20.0 25.1 38.3 19.0 23.2 36.7 31.0 FAM32A "DKFZP586O0120, OTAG-12" ENSG00000105058 "Family with sequence similarity 32 member A" Q9Y421 19 16185380-16192046 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051712 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA051712: AB_2681582" "unprognostic (3.20e-2)" "unprognostic (1.44e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-3)" "unprognostic (1.23e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (1.37e-2)" "unprognostic (3.86e-3)" "unprognostic (1.18e-3)" "unprognostic (1.56e-1)" "unprognostic (9.31e-2)" "unprognostic (3.23e-2)" "unprognostic (4.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" "unprognostic (6.49e-3)" 64.5 69.9 64.9 48.2 66.4 94.6 57.1 60.5 69.3 44.6 57.3 68.8 78.2 57.2 49.5 69.6 45.3 53.8 54.8 66.2 62.1 60.7 95.3 51.4 60.9 62.9 63.1 43.3 52.8 54.0 37.8 61.4 63.5 50.0 57.8 28.1 56.3 47.4 50.8 73.3 74.9 52.9 60.1 67.7 68.9 30.6 65.8 64.1 48.6 49.1 59.5 63.4 49.8 64.3 102.8 76.7 118.3 76.8 137.1 104.7 111.8 97.1 109.8 117.5 128.3 106.1 120.4 67.6 165.2 126.4 84.4 76.8 122.4 106.2 102.6 89.6 134.2 125.5 66.2 95.6 110.4 159.4 141.0 121.6 109.4 94.5 86.2 103.8 128.4 137.2 100.2 96.6 117.6 136.0 124.4 165.9 170.6 168.9 187.7 129.3 81.9 111.6 129.6 100.6 101.6 154.3 82.3 77.2 107.8 84.5 65.5 179.5 120.5 90.8 53.9 167.4 123.5 114.5 204.5 107.8 132.0 191.7 80.2 278.1 266.5 547.9 127.5 339.2 136.3 152.9 122.0 140.3 228.8 159.1 146.2 160.5 220.6 161.5 390.0 157.5 185.6 343.3 64.9 66.4 60.5 69.3 66.2 62.1 62.9 63.1 63.5 60.1 65.8 64.3 59.2 44.8 46.2 3.3 54.7 46.7 32.4 61.7 40.9 26.8 56.5 51.9 36.8 55.8 45.6 36.8 20.9 100.9 65.3 119.8 92.0 102.1 17.9 39.5 56.5 58.7 67.8 49.6 6.2 103.5 108.2 52.5 40.2 53.3 62.7 55.0 45.7 99.8 86.5 42.1 6.9 63.8 34.6 75.5 45.8 40.7 38.8 57.2 58.7 6.5 93.4 56.4 84.5 7.1 7.1 136.4 157.3 52.3 49.1 49.6 120.1 85.5 37.8 24.5 26.3 27.9 61.0 26.5 44.3 47.7 53.3 105.8 53.5 56.0 59.6 54.8 FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 264.8;intestine: 488.7;salivary gland: 468.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 794.8;Intestinal goblet cells: 1150.1;Paneth cells: 776.7;Proximal enterocytes: 353.1;Undifferentiated cells: 760.0" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 151.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Cell line enriched" "Detected in some" 65 "OE19: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" NA NA 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA013844: AB_2668897" "prognostic favorable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" 0.9 0.1 0.2 29.6 0.1 0.0 18.5 0.0 0.5 31.3 0.1 362.0 89.2 0.6 0.2 264.8 0.8 81.6 0.2 0.2 0.1 1.1 0.2 4.8 0.6 0.1 0.2 0.1 1.7 0.0 0.4 1.0 0.1 14.8 488.7 0.0 468.4 68.4 0.1 2.6 90.4 8.3 0.1 0.2 78.2 0.3 0.3 0.4 1.5 0.0 41.1 12.7 59.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.1 0.4 0.2 68.5 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.2 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.7 0.0 0.3 0.0 0.0 0.4 0.2 0.1 0.0 0.5 0.2 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.6 0.0 1.1 0.3 3.4 0.0 9.9 223.1 0.0 0.0 29.5 53.8 0.2 47.1 133.4 14.7 0.0 0.0 1.3 794.8 0.0 1.3 0.5 0.0 0.0 2.5 152.1 0.0 0.1 0.0 0.0 0.8 114.2 0.2 8.9 0.0 0.4 0.2 0.3 0.0 0.1 1150.1 18.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 776.7 0.0 0.2 68.2 353.1 1.2 43.1 0.0 0.0 0.0 4.9 0.1 0.6 7.9 0.1 0.4 2.0 0.0 760.0 245.0 FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Paneth cells: 153.6;Peritubular cells: 191.5;Proximal enterocytes: 145.9;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 255.9;TIME: 420.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 32.4 17.9 2.7 21.5 3.3 0.8 28.1 3.2 4.8 43.2 5.2 75.6 82.2 75.7 15.6 24.1 43.5 69.8 45.6 2.5 2.4 26.7 7.1 39.3 9.6 2.6 3.2 39.1 27.5 36.2 11.0 29.4 2.9 47.0 53.2 1.8 31.7 63.1 5.4 16.8 86.1 47.1 2.5 27.6 64.0 12.8 3.8 2.8 17.6 5.6 6.8 44.6 29.3 2.6 34.2 17.2 15.9 0.6 3.7 8.1 21.6 55.2 84.3 38.4 30.4 6.0 48.8 0.3 114.5 87.8 67.3 62.5 11.3 121.0 19.2 0.3 6.6 0.2 4.7 31.7 98.5 0.2 0.6 39.7 81.7 31.9 75.1 82.7 255.9 2.0 1.2 7.6 13.2 0.8 0.6 1.1 16.5 50.9 25.0 0.1 0.4 1.0 51.4 22.1 0.2 38.9 29.0 3.4 6.0 33.9 6.8 0.6 420.4 50.7 7.1 0.8 25.7 0.4 1.0 0.5 8.0 0.2 0.5 1.7 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.2 0.4 0.1 0.1 2.7 3.3 3.2 4.8 2.5 2.4 2.6 3.2 2.9 2.5 3.8 2.6 10.8 12.8 18.1 0.0 3.1 86.3 82.7 41.4 20.5 3.7 28.6 23.9 37.1 47.1 30.6 16.5 6.2 8.9 4.8 207.3 0.0 99.1 3.4 13.6 75.9 19.2 46.0 0.0 0.7 53.5 114.2 29.3 133.5 20.5 18.9 9.4 55.0 2.5 5.6 1.7 5.5 54.8 26.4 1.9 23.5 4.0 80.2 5.8 14.2 2.8 2.7 9.1 1.0 1.0 1.2 113.0 153.6 191.5 1.2 29.8 145.9 2.5 11.6 6.4 144.7 11.9 64.8 2.8 1.9 17.4 62.8 19.4 6.0 6.6 53.8 62.6 FBXL19 "CXXC11, DKFZp434K0410, Fbl19, JHDM1C" ENSG00000099364 "F-box and leucine rich repeat protein 19" Q6PCT2 16 30923055-30948783 "Predicted intracellular proteins" "Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074250 Approved Nucleoplasm NA No "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA074250: " "unprognostic (1.37e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.03e-1)" "unprognostic (3.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (3.61e-2)" "unprognostic (2.52e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (6.95e-3)" "unprognostic (1.37e-3)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" 5.4 7.7 16.5 9.8 14.8 8.3 5.5 4.4 27.9 8.7 1.9 8.6 10.4 8.5 4.0 16.5 7.3 8.5 5.6 16.8 10.1 11.5 4.3 5.8 9.7 9.4 8.6 8.4 6.7 7.2 11.4 10.1 9.1 9.9 3.8 8.5 8.9 5.4 4.8 12.7 8.8 4.6 3.1 9.9 8.7 30.0 12.4 10.0 7.9 4.0 5.1 8.5 9.6 14.4 17.5 46.0 44.7 35.6 8.0 8.1 38.6 24.2 12.3 18.3 17.2 24.8 23.9 27.1 27.4 14.4 14.2 24.3 35.9 25.8 14.0 76.3 110.0 30.0 84.0 36.5 9.9 33.5 69.9 8.3 20.4 22.6 16.0 15.9 30.0 37.7 80.0 26.3 10.3 46.9 36.4 46.2 44.4 13.0 15.5 73.1 14.2 27.0 17.7 23.6 29.6 56.3 8.5 53.0 13.7 25.1 32.5 34.8 30.0 20.2 26.1 13.5 17.1 23.1 20.4 16.9 24.7 49.0 29.9 0.0 0.4 0.5 0.3 0.2 0.3 0.5 0.1 0.1 0.2 0.2 0.0 0.3 0.5 0.9 0.0 0.7 0.2 0.1 16.5 14.8 4.4 27.9 16.8 10.1 9.4 8.6 9.1 3.1 12.4 14.4 3.4 0.0 1.1 4.9 1.5 8.3 2.4 2.5 2.8 6.1 6.8 4.1 1.5 4.3 2.9 3.7 12.5 5.7 4.0 8.9 0.0 6.1 5.6 3.8 4.7 5.0 2.4 1.3 4.5 7.1 5.4 3.1 3.6 6.0 0.0 8.9 3.6 2.3 5.2 1.7 5.0 6.5 2.0 2.8 3.9 6.5 1.5 3.4 0.0 3.7 3.3 2.8 4.1 3.0 2.1 8.6 4.1 2.6 1.7 6.4 3.3 5.1 1.8 6.0 6.6 2.2 3.5 4.7 2.9 5.4 8.9 9.3 2.0 4.9 8.5 6.5 FBXL8 Fbl8 ENSG00000135722 "F-box and leucine rich repeat protein 8" Q96CD0 16 67159932-67164570 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035587, HPA035588" Uncertain Approved "Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA035587: AB_2674690, HPA035588: AB_10670023" "unprognostic (1.31e-1)" "unprognostic (1.95e-1)" "unprognostic (3.57e-2)" "prognostic favorable (5.39e-4)" "unprognostic (3.79e-1)" "unprognostic (3.27e-2)" "unprognostic (2.94e-2)" "unprognostic (9.14e-2)" "unprognostic (1.21e-1)" "unprognostic (4.67e-1)" "unprognostic (1.06e-2)" "unprognostic (2.22e-2)" "unprognostic (1.13e-3)" "unprognostic (2.68e-1)" "unprognostic (3.88e-2)" "unprognostic (1.47e-1)" "unprognostic (7.17e-3)" 12.2 24.0 3.1 5.4 4.2 3.4 18.4 5.3 5.7 17.7 1.7 16.6 9.8 17.0 2.5 15.6 20.3 2.3 10.9 3.7 1.7 14.6 16.7 14.6 4.3 5.2 3.2 16.2 53.5 4.9 24.9 5.7 4.3 35.5 6.4 2.2 35.8 2.6 11.2 30.1 12.2 2.5 2.2 13.5 22.6 4.3 3.9 2.0 20.9 1.2 2.7 12.7 14.9 8.6 5.9 7.2 1.1 9.7 5.2 9.2 25.0 4.9 4.0 4.0 4.0 6.8 16.0 4.6 7.4 4.6 4.0 19.9 2.9 4.8 1.1 11.9 11.7 4.7 17.2 7.5 3.7 2.7 18.1 6.9 5.2 4.2 3.4 11.6 2.6 12.6 9.3 10.1 2.8 16.8 3.9 10.4 0.6 5.4 17.6 12.7 3.3 22.4 6.1 8.1 10.2 9.5 12.4 6.4 3.3 2.9 31.7 6.2 6.3 10.0 11.5 23.4 4.4 43.4 10.4 6.0 11.0 8.7 6.1 5.1 4.7 4.9 3.8 2.2 3.4 1.6 10.7 5.0 2.4 1.7 2.3 2.4 6.4 5.8 2.0 4.3 4.0 3.1 3.1 4.2 5.3 5.7 3.7 1.7 5.2 3.2 4.3 2.2 3.9 8.6 3.4 0.0 3.1 0.0 2.8 3.2 4.4 3.4 17.1 1.7 5.0 4.3 0.9 7.2 5.1 5.5 8.4 2.8 6.0 7.6 1.9 6.9 0.1 3.3 3.4 3.2 6.7 0.4 0.2 8.0 3.1 4.6 18.8 3.7 0.0 4.7 1.8 4.4 2.8 5.0 0.1 10.4 2.0 1.9 2.9 0.5 9.3 2.9 10.6 0.0 7.7 1.9 8.2 0.0 1.1 9.3 5.2 5.7 4.6 5.4 10.6 6.2 4.1 4.7 6.6 2.4 4.2 0.1 1.0 7.2 4.4 1.5 4.2 8.4 9.0 5.6 FBXO32 "ATROGIN1, Fbx32, MAFbx" ENSG00000156804 "F-box protein 32" Q969P5 8 123497889-123541206 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 649.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 247.5;Cardiomyocytes: 286.5;Prostatic glandular cells: 225.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 2.9;gdT-cell: 2.5;MAIT T-cell: 2.5;memory CD4 T-cell: 3.6;memory CD8 T-cell: 3.8;naive CD4 T-cell: 4.2;naive CD8 T-cell: 5.4;NK-cell: 3.2;T-reg: 3.8" "Group enriched" "Detected in many" 8 "granulocytes: 2.9;NK-cells: 3.2;T-cells: 5.4" "Cell line enhanced" "Detected in many" "GAMG: 49.3;HDLM-2: 176.1;hTERT-RPE1: 58.3;U-251 MG: 51.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058955, HPA065209" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA058955: , HPA065209: AB_2685433" "unprognostic (2.55e-1)" "unprognostic (3.62e-1)" "unprognostic (1.80e-1)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.31e-1)" "unprognostic (1.10e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (8.58e-3)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (7.97e-3)" 10.9 2.7 13.2 13.9 19.6 2.2 29.2 20.0 15.5 15.0 41.4 136.6 6.7 86.9 14.9 16.2 59.5 32.5 77.9 10.6 15.1 2.7 1.1 3.8 6.0 27.4 20.3 24.9 4.6 11.7 8.9 7.7 28.8 25.8 20.7 17.9 23.0 43.8 649.5 12.9 23.5 94.9 21.5 3.9 31.8 1.7 15.9 9.2 24.3 105.6 5.1 73.3 13.8 28.6 5.3 0.9 0.2 0.0 10.6 2.5 1.9 1.0 11.4 0.6 1.1 0.0 2.9 0.0 3.1 8.5 49.3 0.3 0.2 1.0 0.9 176.1 4.0 0.0 6.3 0.0 14.5 0.1 0.7 21.1 7.4 2.6 3.2 58.3 0.8 2.5 0.3 1.5 0.8 1.3 0.7 0.1 0.1 2.1 0.9 0.0 0.2 1.1 1.9 1.7 0.3 1.1 1.2 19.2 21.5 1.1 18.9 0.4 0.7 3.1 0.8 1.1 51.9 17.4 2.6 0.4 12.7 0.2 2.5 2.9 0.2 0.0 2.5 0.1 2.5 0.4 3.6 3.8 0.2 0.4 4.2 5.4 0.1 3.2 0.2 0.1 3.8 1.1 13.2 19.6 20.0 15.5 10.6 15.1 27.4 20.3 28.8 21.5 15.9 28.6 6.8 0.0 3.7 7.5 6.1 11.5 184.8 113.3 64.9 17.7 44.9 247.5 286.5 4.3 63.6 7.3 35.5 17.8 27.9 153.0 9.8 14.4 4.7 22.2 88.2 13.0 102.4 8.0 52.2 30.7 17.5 28.9 14.8 76.0 0.0 30.3 2.2 2.9 5.3 21.9 30.9 63.6 111.9 5.9 3.4 3.5 39.7 5.6 44.4 14.0 2.4 58.6 25.7 9.5 117.2 51.7 189.5 61.3 38.3 225.2 36.9 5.2 19.9 100.1 19.7 75.2 61.3 15.9 2.9 49.9 6.3 109.2 32.5 3.7 21.1 90.8 FEM1C "EUROIMAGE686608, EUROIMAGE783647, FEM1A, KIAA1785" ENSG00000145780 "Fem-1 homolog C" Q96JP0 5 115520908-115544775 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059919, HPA060977" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA059919: AB_2684161, HPA060977: AB_2684402" "unprognostic (1.14e-2)" "unprognostic (3.02e-1)" "prognostic favorable (1.83e-4)" "unprognostic (1.28e-1)" "unprognostic (3.31e-1)" "unprognostic (7.56e-2)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (4.67e-2)" "unprognostic (5.52e-3)" "unprognostic (1.99e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (1.37e-2)" "unprognostic (1.05e-2)" 13.6 5.6 6.1 7.9 9.5 63.2 10.6 13.4 10.7 12.5 1.1 13.3 11.1 9.8 6.1 14.7 6.1 12.3 15.7 5.3 4.4 7.4 15.7 11.1 6.9 6.3 7.2 7.6 11.0 5.5 4.2 6.2 5.4 9.7 12.2 17.1 5.8 6.9 20.6 10.1 12.1 10.3 4.8 8.5 10.6 13.6 9.5 6.6 8.2 21.3 6.6 9.8 7.7 7.9 11.8 7.0 9.8 15.3 17.3 24.1 7.9 18.3 14.5 13.5 15.6 7.7 10.2 12.0 12.2 13.5 15.5 9.0 8.0 15.2 19.7 18.6 7.6 6.3 9.7 5.9 11.5 4.2 8.2 15.9 12.6 16.8 15.1 12.5 13.4 9.8 4.0 15.3 20.5 5.1 11.0 7.1 6.9 7.5 8.7 9.3 17.9 13.1 14.9 22.1 8.0 6.5 11.8 8.1 20.1 7.8 10.5 8.4 23.7 23.0 12.0 21.3 16.4 12.0 9.4 9.4 13.4 11.6 9.5 2.5 4.7 5.0 2.7 6.9 3.9 2.3 2.8 2.0 4.6 1.3 3.1 2.6 4.8 2.2 8.8 1.2 3.4 2.8 6.1 9.5 13.4 10.7 5.3 4.4 6.3 7.2 5.4 4.8 9.5 7.9 35.4 22.4 13.6 28.4 15.3 26.5 15.8 7.8 18.8 17.2 17.6 13.0 31.5 20.0 14.8 11.0 20.9 4.4 15.8 64.7 5.9 11.6 48.1 31.1 33.0 18.8 16.7 12.2 13.3 8.4 8.6 27.5 23.0 36.9 13.3 29.6 17.9 47.0 7.6 5.0 7.2 27.5 8.2 15.8 52.9 80.7 8.7 22.5 30.2 5.6 9.7 23.1 5.2 15.1 18.2 17.1 53.2 6.8 19.4 18.9 31.7 12.3 18.3 28.2 0.0 24.0 22.8 16.5 6.3 25.4 24.7 5.1 16.7 8.0 21.5 40.2 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FOXD2 "FKHL17, FREAC9" ENSG00000186564 "Forkhead box D2" O60548 1 47438044-47440691 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.8" "Group enriched" "Detected in some" 4 "Distal enterocytes: 22.2;Enteroendocrine cells: 9.1;Intestinal goblet cells: 12.6;Paneth cells: 11.1;Sertoli cells: 6.6;Undifferentiated cells: 18.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 3.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AN3-CA: 14.4;WM-115: 23.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "spinal cord: 4.0" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.10e-2)" "unprognostic (4.55e-2)" "unprognostic (4.17e-2)" "unprognostic (1.49e-1)" "unprognostic (6.39e-2)" "unprognostic (9.85e-3)" "unprognostic (2.81e-3)" "unprognostic (1.92e-1)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (4.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.79e-12)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "unprognostic (9.58e-2)" "unprognostic (5.91e-2)" 0.4 0.8 0.3 0.6 0.4 0.0 0.3 0.3 1.0 1.1 2.1 5.8 0.3 0.3 0.2 0.1 0.3 0.0 0.1 0.2 0.6 1.9 0.6 0.3 0.1 0.1 1.4 0.1 0.1 0.1 1.1 0.2 0.2 1.3 4.6 0.2 0.3 0.2 0.2 0.2 0.4 0.1 0.2 0.6 0.7 0.4 0.3 0.1 0.2 1.0 0.0 0.2 0.4 0.2 0.8 0.4 0.0 14.4 0.1 0.1 0.4 0.4 0.1 0.0 0.1 1.0 0.2 0.2 0.6 0.0 1.2 0.2 0.6 0.0 0.0 1.8 2.3 0.5 0.3 0.1 0.0 0.2 1.3 0.0 0.8 0.0 0.0 0.3 0.0 0.8 0.4 0.1 0.1 0.4 0.2 0.6 0.0 0.4 0.5 1.9 1.1 0.7 0.0 0.9 2.0 0.0 0.6 0.8 2.0 0.4 4.0 1.1 0.3 0.5 1.5 0.1 0.7 0.4 0.2 0.3 0.6 0.9 23.2 0.2 0.1 0.4 0.5 0.1 0.4 0.2 0.2 0.4 0.0 0.2 0.1 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.3 0.4 0.3 1.0 0.2 0.6 0.1 1.4 0.2 0.2 0.3 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.3 0.1 1.3 0.0 0.2 0.0 0.0 0.0 1.4 22.2 0.0 0.2 0.4 0.1 1.1 0.3 9.1 0.0 0.0 0.7 0.0 0.8 1.1 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.0 12.6 0.0 1.4 0.8 1.1 0.0 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 11.1 0.7 0.0 0.0 1.3 0.2 0.4 0.2 6.6 0.2 2.0 0.7 1.5 0.0 0.1 0.0 1.0 0.0 18.1 0.0 FOXH1 FAST1 ENSG00000160973 "Forkhead box H1" O75593 8 144473412-144475849 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 2.1;skin 1: 1.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 3.4;Spermatogonia: 1.7" "Cancer enriched" "Detected in some" 26 "testis cancer: 23.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NTERA-2: 26.6;SuSa: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.62e-1)" "unprognostic (8.26e-2)" "unprognostic (4.70e-2)" "unprognostic (2.23e-2)" "unprognostic (2.10e-1)" "unprognostic (1.65e-1)" "unprognostic (1.09e-2)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (6.20e-2)" "unprognostic (3.99e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-8)" "unprognostic (1.03e-1)" "unprognostic (3.39e-2)" "unprognostic (3.99e-1)" "unprognostic (9.35e-3)" 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.0 0.0 1.1 0.4 0.0 0.0 0.4 0.0 0.2 0.3 0.1 0.2 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.4 0.2 2.1 0.2 0.0 0.0 1.4 0.7 0.0 0.0 0.2 0.5 1.1 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.3 0.4 0.0 0.0 0.7 0.0 0.3 26.6 0.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 6.9 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.4 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.3 1.7 0.0 0.1 0.0 0.1 0.4 0.7 0.1 FP565260.2 ENSG00000276612 "Novel protein" 21 5116343-5133805 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 11.1;Enteroendocrine cells: 3.5;granulocytes: 11.4;Intestinal goblet cells: 9.0;Paneth cells: 6.6;Undifferentiated cells: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 2.6;RH-30: 3.4;SK-MEL-30: 2.9;U-937: 2.7" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" 0.4 0.7 1.0 0.0 1.1 0.0 0.0 1.3 2.5 0.2 0.5 0.1 0.7 0.1 0.0 0.1 0.2 0.0 0.2 1.3 0.6 0.2 0.2 0.1 0.0 0.9 0.8 0.1 0.0 0.1 0.1 0.0 0.9 0.1 0.0 1.1 0.0 0.0 0.4 0.1 0.1 0.3 0.6 0.3 0.1 0.2 0.8 0.1 0.1 0.0 0.1 0.2 0.1 1.0 0.0 0.8 0.2 1.1 2.4 0.5 0.3 0.3 0.0 0.3 0.1 0.8 0.0 0.0 0.0 0.0 1.0 0.0 1.6 1.4 0.3 1.0 0.3 2.6 0.4 0.6 1.4 0.0 0.2 0.5 0.0 1.6 1.6 1.2 0.6 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 3.4 1.1 0.0 0.0 2.1 0.1 0.5 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.3 0.0 0.7 0.2 2.7 0.8 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.8 0.1 0.0 0.0 1.0 1.1 1.3 2.5 1.3 0.6 0.9 0.8 0.9 0.6 0.8 1.0 0.0 0.0 3.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.7 3.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 12.5 0.0 FRMD1 "bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260" ENSG00000153303 "FERM domain containing 1" Q8N878 6 168053166-168101511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;lymphoid tissue: 13.1;stomach 1: 5.7;testis: 5.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 68.9;Paneth cells: 167.2" "Cancer enriched" "Detected in single" 6 "colorectal cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 1.9;RPMI-8226: 3.0" "Low region specificity" "Detected in many" HPA030347 Enhanced Approved "Actin filaments" NA NA "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "HPA030347: AB_10600207" "unprognostic (2.43e-2)" "unprognostic (2.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.58e-4)" "unprognostic (8.63e-2)" "unprognostic (2.62e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.01e-1)" "unprognostic (9.11e-3)" 3.6 0.0 0.0 0.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 3.1 0.1 0.0 2.1 5.7 5.1 0.0 13.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 1.8 0.0 0.0 0.0 68.9 0.0 0.0 15.3 0.0 0.0 0.2 7.8 0.0 0.0 1.8 0.0 0.4 4.6 0.1 0.0 0.3 0.4 0.6 0.0 0.0 0.0 16.0 0.0 0.0 0.0 20.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 1.5 0.0 0.0 19.6 23.8 0.0 0.0 0.0 0.3 0.7 13.4 8.2 0.0 0.0 0.1 0.1 15.2 12.6 0.2 FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851474 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.7;intestine: 72.3;retina: 79.3;salivary gland: 84.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.7;Intestinal goblet cells: 78.7;Pancreatic endocrine cells: 49.0;Paneth cells: 88.9;Proximal enterocytes: 85.2;Undifferentiated cells: 65.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 46.3;hTCEpi: 6.9;OE19: 20.6;RH-30: 14.8;SK-BR-3: 7.1" HPA046966 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046966: AB_2679879" "prognostic unfavorable (6.86e-4)" "unprognostic (2.59e-1)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (8.58e-3)" "unprognostic (1.63e-3)" "unprognostic (3.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "prognostic favorable (8.22e-7)" "unprognostic (5.66e-3)" "unprognostic (9.56e-2)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" 0.5 0.0 0.4 12.6 0.6 0.7 1.2 0.5 0.7 25.9 0.5 72.3 47.7 0.3 0.0 158.7 1.3 22.4 0.2 0.4 1.2 9.8 2.3 5.2 0.1 0.8 0.5 0.1 9.1 0.0 0.6 0.1 0.7 2.2 44.5 79.3 84.2 8.5 0.1 3.2 56.3 2.8 0.2 0.2 20.8 4.0 0.6 0.2 0.0 0.0 15.9 3.0 53.2 0.7 46.3 0.0 0.2 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 5.2 0.0 0.6 0.0 0.0 2.0 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 6.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 20.6 0.0 0.0 14.8 1.6 0.0 0.6 0.0 0.2 0.0 7.1 0.2 0.1 0.1 0.4 0.0 0.2 0.1 0.1 0.3 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.6 0.5 0.7 0.4 1.2 0.8 0.5 0.7 0.2 0.6 0.7 0.1 0.0 4.8 0.3 1.1 0.0 3.0 23.6 0.0 1.8 1.7 0.3 0.3 11.5 36.4 0.0 0.0 0.1 0.0 154.7 0.0 43.2 4.9 1.1 0.1 0.5 13.8 0.0 0.1 14.2 0.4 0.0 18.3 0.6 8.9 0.1 0.0 0.4 0.0 0.0 0.0 78.7 14.2 0.0 0.0 8.7 0.0 0.2 0.0 1.0 0.0 1.9 0.0 0.0 0.1 49.0 88.9 0.0 0.1 0.9 85.2 16.5 22.8 34.9 0.0 0.0 1.5 0.5 0.2 6.5 0.0 0.3 0.5 0.0 65.6 27.3 FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115879-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1800.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1870.8;Distal enterocytes: 5605.4;Intestinal goblet cells: 2165.8;Paneth cells: 3324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 896.3;hTCEpi: 1603.2;OE19: 3112.0;RT4: 860.2;SK-BR-3: 830.8;WM-115: 589.7" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" 5.1 1.1 7.3 59.5 7.4 1.3 225.2 7.1 7.9 168.0 7.5 1466.2 102.7 13.2 15.2 685.3 104.3 100.5 5.8 7.1 6.5 12.0 2.0 150.2 0.8 8.0 7.3 1.8 64.3 0.1 24.7 84.9 6.8 512.1 1800.0 45.4 569.1 33.3 2.1 568.3 308.9 35.7 6.7 0.6 572.4 0.6 7.0 18.7 1.5 0.1 163.3 295.6 395.8 7.4 166.3 0.0 0.0 0.4 0.6 0.4 150.5 0.0 0.0 0.0 0.0 6.0 235.3 0.3 0.5 0.0 1.3 896.3 0.1 339.5 0.0 0.1 0.3 1.0 7.7 0.6 0.1 0.1 0.6 0.0 1603.2 0.0 0.7 0.1 0.1 0.1 0.1 1.1 0.0 304.5 0.8 2.2 0.8 3112.0 1.4 0.8 0.4 1.2 0.0 860.2 190.2 2.1 1.0 830.8 61.8 2.3 155.9 0.2 0.0 0.3 0.6 0.9 0.7 0.1 0.4 0.7 1.0 0.3 589.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 7.3 7.4 7.1 7.9 7.1 6.5 8.0 7.3 6.8 6.7 7.0 7.4 3.1 762.8 262.6 0.3 11.1 576.9 792.9 1870.8 340.4 2.9 557.5 515.7 1.3 201.6 1026.4 134.3 0.0 883.5 8.3 5605.4 1.9 35.6 0.4 180.1 29.5 19.7 974.3 2.7 0.1 708.4 138.1 20.3 356.8 194.1 22.3 0.0 0.0 0.9 81.4 1.7 0.0 2165.8 587.9 0.0 68.3 0.0 0.0 15.6 412.6 0.0 1.6 422.1 0.0 0.0 0.6 556.5 3324.0 0.0 6.5 1041.7 1693.0 0.5 1627.1 13.3 0.0 0.5 66.5 0.2 0.2 541.1 865.5 1512.1 17.9 0.0 1499.3 1509.9 FZD5 "C2orf31, DKFZP434E2135, HFZ5" ENSG00000163251 "Frizzled class receptor 5" Q13467 2 207762598-207769906 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 23.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 117.4;Hepatocytes: 59.8;Intestinal goblet cells: 50.1;Muller glia cells: 50.7;Undifferentiated cells: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 104.7;CACO-2: 26.2;Hep G2: 36.5;NTERA-2: 31.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052361 Approved NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052361: AB_2681799" "unprognostic (4.97e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" "unprognostic (1.53e-1)" "unprognostic (2.82e-1)" "unprognostic (4.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-3)" "unprognostic (1.29e-1)" "unprognostic (8.00e-2)" "unprognostic (7.72e-2)" "unprognostic (2.51e-1)" "unprognostic (9.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.15e-3)" 6.0 5.0 1.8 2.5 3.5 4.2 2.4 1.8 3.6 3.0 3.5 18.3 18.6 2.3 0.6 3.3 1.2 1.4 1.6 1.7 3.6 5.1 23.5 6.7 1.1 3.2 4.9 4.2 10.4 1.0 4.7 4.4 2.5 6.3 14.7 10.9 3.1 2.7 2.6 1.0 15.3 2.6 1.8 2.0 11.2 0.4 2.7 1.5 8.7 2.0 1.4 1.7 2.3 6.2 3.3 5.8 0.3 3.1 2.6 0.1 104.7 0.5 0.7 0.8 0.7 26.2 6.0 0.6 7.0 0.3 2.0 4.8 9.0 3.9 0.7 0.4 6.9 7.6 2.8 36.5 2.0 1.5 2.0 0.2 3.7 1.2 3.0 2.0 1.0 1.1 15.5 1.2 0.7 2.3 0.8 1.9 31.0 14.2 2.0 1.9 3.3 1.4 7.3 11.4 5.0 0.7 1.4 0.6 1.5 14.1 1.7 1.5 0.4 1.6 3.0 3.2 2.5 1.7 4.1 1.3 2.1 1.7 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.5 1.8 3.6 1.7 3.6 3.2 4.9 2.5 1.8 2.7 6.2 6.5 32.1 32.6 4.6 2.0 5.1 5.4 5.4 6.2 2.2 8.7 3.7 7.8 25.8 4.8 1.8 33.3 18.9 1.6 117.4 0.0 14.9 0.7 9.0 2.2 4.1 12.6 15.1 0.5 24.7 6.0 3.2 17.3 18.8 0.0 16.8 2.9 59.8 10.5 6.7 0.9 50.1 6.1 8.4 9.8 0.1 1.8 3.3 1.8 1.0 0.7 50.7 0.0 0.0 6.0 18.2 38.6 0.4 0.5 12.5 43.2 12.2 3.4 7.0 0.0 8.1 4.5 1.5 2.1 4.0 4.1 4.0 1.4 8.1 57.6 5.9 GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA027405: AB_10611111, HPA027459: AB_10599948, HPA027463: AB_10601959" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-3)" "unprognostic (1.07e-1)" "unprognostic (3.50e-3)" "unprognostic (1.68e-1)" "unprognostic (7.07e-2)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.70e-6)" "unprognostic (1.09e-3)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "prognostic favorable (7.41e-4)" 31.9 40.7 21.1 25.9 22.5 35.5 34.0 20.1 29.7 42.7 20.1 56.3 51.2 41.9 8.0 49.7 43.0 17.7 25.4 21.5 17.8 55.0 47.7 46.0 25.6 28.7 19.8 40.5 53.1 22.7 37.1 15.6 22.1 41.8 14.8 9.4 71.0 13.3 31.4 40.4 57.4 9.8 17.7 61.5 54.2 45.8 20.6 21.6 38.5 6.6 12.9 38.7 39.3 20.5 36.0 28.3 16.9 29.0 16.6 14.2 43.6 33.0 19.7 22.3 18.5 35.9 49.8 30.4 20.9 20.1 40.3 29.7 17.7 27.4 10.5 30.7 27.9 35.3 29.5 27.5 31.1 36.2 53.0 20.5 23.2 22.7 11.0 14.2 24.7 35.3 38.4 37.4 15.2 34.7 61.6 92.1 30.4 38.2 46.3 50.2 19.4 27.4 18.2 28.8 29.0 31.3 19.3 24.2 23.3 14.1 39.2 30.7 40.8 30.9 18.0 31.8 45.1 59.5 41.3 33.8 34.9 43.7 29.0 3.0 10.3 12.8 8.8 9.8 7.6 4.9 5.8 6.1 6.5 3.9 3.3 4.8 7.4 4.8 24.6 7.6 5.6 9.4 21.1 22.5 20.1 29.7 21.5 17.8 28.7 19.8 22.1 17.7 20.6 20.5 24.7 25.6 33.2 34.0 33.9 17.0 15.3 17.9 14.8 27.2 25.3 17.7 12.2 18.6 28.2 25.8 64.6 19.0 46.2 131.3 9.8 18.8 99.1 32.2 21.6 26.7 29.4 26.1 25.7 28.0 17.5 19.5 93.8 52.5 18.3 31.2 18.5 31.6 36.6 11.8 23.5 66.5 26.4 35.9 18.4 134.7 25.1 35.5 16.0 59.0 28.8 16.3 35.0 9.0 24.4 37.6 71.1 18.8 26.1 28.4 65.8 31.0 33.8 26.9 19.7 17.9 18.0 32.9 27.4 19.9 22.3 31.1 34.6 41.6 65.0 44.6 GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 331.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" 28.9 20.6 11.9 27.4 12.1 26.0 37.2 12.3 14.2 26.5 15.1 42.8 42.9 19.4 19.7 57.6 15.9 28.9 23.8 10.9 14.4 17.4 45.9 23.3 33.5 13.1 13.2 16.9 24.6 12.2 13.5 52.0 13.5 25.4 41.1 17.1 46.8 18.0 29.0 52.4 49.3 22.7 13.1 25.4 27.1 16.9 13.1 18.6 30.0 37.3 40.8 70.5 27.0 13.9 32.5 34.9 40.5 37.6 78.5 74.0 53.4 33.2 35.4 30.3 27.4 21.0 61.9 38.3 34.9 36.0 28.7 24.4 20.2 63.8 48.1 45.0 18.5 48.7 62.8 48.8 39.2 106.6 62.1 50.7 59.7 47.6 52.1 90.1 331.4 30.8 14.8 49.3 118.9 26.1 31.6 40.5 41.6 33.5 16.4 38.9 53.0 18.5 124.8 148.9 21.8 42.9 59.4 43.0 36.2 77.1 32.9 82.8 116.3 55.7 22.5 37.0 37.1 70.1 35.7 72.5 39.1 72.1 29.5 7.2 3.4 7.6 3.2 4.5 3.6 4.1 2.2 2.9 4.0 2.4 2.0 3.0 4.3 4.6 6.6 4.4 2.5 1.4 11.9 12.1 12.3 14.2 10.9 14.4 13.1 13.2 13.5 13.1 13.1 13.9 85.6 80.1 44.1 35.9 33.4 29.8 28.4 28.8 22.2 31.3 77.2 43.8 43.3 48.6 39.9 16.5 12.5 31.0 44.8 109.1 7.9 42.6 1.4 77.6 44.7 41.7 38.9 30.9 57.5 39.9 92.7 49.8 26.0 73.0 20.3 51.7 35.7 71.3 77.9 85.8 56.3 59.0 16.2 58.8 37.1 2.9 19.0 56.7 19.6 57.1 41.3 105.9 28.8 54.3 56.8 58.5 51.4 18.0 36.7 54.4 76.8 22.0 33.5 28.5 13.1 55.2 28.7 6.5 12.2 26.3 82.1 33.2 33.7 50.3 85.3 52.8 GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.8;ovary: 73.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.6;Gastric mucus-secreting cells: 100.9;Granulosa cells: 52.9" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Cell line enhanced" "Detected in many" "BEWO: 54.8;CACO-2: 69.7;hTERT-RPE1: 25.5;OE19: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB011581: AB_732529, HPA066629: AB_2685695" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (2.16e-1)" "unprognostic (9.43e-2)" "unprognostic (4.36e-2)" "unprognostic (3.47e-1)" "unprognostic (2.61e-1)" "unprognostic (8.45e-3)" "prognostic unfavorable (1.92e-9)" "unprognostic (8.75e-3)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-2)" 22.2 57.8 0.0 2.5 0.2 0.0 3.8 0.0 0.3 4.9 2.8 11.4 22.8 19.8 1.2 0.8 28.9 11.1 43.9 0.1 0.0 3.0 12.6 14.8 1.9 0.1 0.0 73.0 22.7 0.3 0.6 6.5 0.0 5.5 11.0 0.1 0.8 0.7 0.8 1.5 20.7 9.5 0.2 15.0 49.6 6.3 0.1 0.4 5.3 0.6 0.2 23.0 3.2 0.0 10.1 1.4 0.0 0.0 2.1 1.0 54.8 0.3 0.4 0.8 1.0 69.7 3.8 0.0 3.2 1.2 3.4 10.8 0.4 4.5 1.4 0.0 13.6 0.0 4.3 6.1 14.3 0.6 0.6 0.4 8.9 12.1 9.1 25.5 9.5 0.0 0.5 0.0 0.0 1.5 0.0 0.2 0.1 37.6 9.8 0.0 1.1 0.2 0.4 2.8 0.9 0.1 10.7 6.1 3.0 2.7 1.7 0.0 0.7 1.4 1.6 11.4 1.7 0.0 0.0 0.0 6.2 0.3 9.9 4.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 7.3 44.8 30.2 0.0 0.0 0.9 4.0 4.6 1.8 0.0 3.4 2.7 97.6 30.0 6.1 0.0 0.0 0.9 0.9 50.0 0.0 28.4 44.7 6.3 6.3 11.5 26.0 2.7 0.1 19.6 11.2 24.4 100.9 16.6 5.1 52.9 28.5 11.1 1.6 0.0 0.1 45.8 2.0 0.6 0.9 8.8 3.4 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.2 36.8 27.7 10.1 0.2 4.1 43.3 0.0 3.9 0.0 32.9 0.4 8.6 1.4 1.4 0.9 0.9 1.9 1.3 11.4 47.2 2.9 GBP3 FLJ10961 ENSG00000117226 "Guanylate binding protein 3" Q9H0R5 1 89006679-89022894 "Predicted intracellular proteins" "Antiviral defense, Immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 78.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.2;Pancreatic endocrine cells: 106.7;Proximal enterocytes: 133.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 80.9;BJ hTERT+ SV40 Large T+ RasG12V: 56.3;LHCN-M2: 71.3" HPA045657 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA045657: AB_10961631" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (6.30e-2)" "unprognostic (1.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" "unprognostic (4.39e-2)" "unprognostic (3.47e-1)" "unprognostic (7.44e-2)" "unprognostic (4.42e-2)" "unprognostic (1.98e-1)" "unprognostic (1.86e-2)" "unprognostic (1.66e-2)" "unprognostic (9.70e-3)" "unprognostic (3.06e-2)" "unprognostic (5.06e-3)" 8.4 9.2 3.5 10.9 3.8 1.6 12.8 3.3 6.3 7.2 2.9 39.1 78.3 8.9 10.0 6.1 15.3 10.8 5.1 3.3 4.7 13.9 14.9 22.8 14.5 5.4 4.2 8.2 5.9 4.1 4.2 13.8 4.4 10.3 27.4 0.6 11.8 20.2 1.8 7.2 59.8 9.3 4.1 16.1 31.7 2.3 4.1 10.0 9.7 4.2 8.6 27.4 7.7 5.0 26.4 1.6 0.0 0.0 24.5 28.6 4.3 44.4 80.9 41.5 56.3 0.0 2.0 1.9 8.5 40.4 24.0 10.9 0.0 29.5 40.2 0.6 0.0 2.5 4.0 0.5 20.8 9.0 0.1 22.3 5.7 31.1 11.0 28.3 13.9 4.2 0.0 5.8 71.3 0.0 6.5 1.1 0.2 14.3 20.0 2.0 4.8 3.1 41.6 49.1 0.0 0.2 14.0 7.9 0.0 0.8 0.1 2.6 17.2 44.6 3.1 0.4 4.8 7.6 2.6 0.1 0.4 0.2 11.4 0.1 6.0 0.3 11.8 7.0 10.5 3.6 10.5 9.8 6.5 2.8 6.5 9.7 3.1 6.9 13.3 0.4 8.6 5.6 3.5 3.8 3.3 6.3 3.3 4.7 5.4 4.2 4.4 4.1 4.1 5.0 20.7 6.4 18.1 2.9 7.3 6.9 25.7 19.4 6.8 0.1 11.5 7.4 1.4 35.8 24.8 22.0 0.0 7.6 12.4 127.2 13.7 59.4 0.1 46.7 15.0 21.2 9.1 5.7 0.3 61.6 8.2 12.5 27.0 35.0 4.5 5.6 22.5 10.6 5.0 0.0 0.2 34.8 14.2 12.0 5.8 1.5 9.9 18.0 0.0 2.8 21.1 0.7 28.8 0.5 0.1 106.7 71.4 15.4 13.6 17.5 133.3 32.8 69.3 0.2 19.7 3.9 8.0 0.5 0.2 5.9 4.8 2.2 21.8 10.9 28.8 37.2 GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 75.5;intestine: 142.9;salivary gland: 55.8" "Cell type enhanced" "Detected in many" "Collecting duct cells: 104.8;Distal enterocytes: 360.1;Ductal cells: 92.6;Glandular and luminal cells: 75.6;Paneth cells: 163.2;Proximal enterocytes: 85.5" "Group enriched" "Detected in many" 4 "colorectal cancer: 16.4;pancreatic cancer: 29.8;stomach cancer: 20.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 147.4;EFO-21: 24.6;Hep G2: 30.3;OE19: 75.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA011154: AB_1078961" "unprognostic (5.09e-2)" "unprognostic (2.39e-1)" "unprognostic (5.92e-2)" "prognostic favorable (1.78e-4)" "unprognostic (3.99e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (6.49e-5)" "unprognostic (1.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.34e-1)" "unprognostic (1.64e-2)" "unprognostic (1.63e-1)" "unprognostic (4.02e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (2.43e-1)" 0.2 0.7 0.2 11.9 0.2 0.5 0.4 0.6 0.4 19.2 0.2 142.9 97.5 2.0 0.0 15.8 4.2 75.5 0.1 0.2 0.1 17.9 0.4 0.7 0.9 0.1 0.4 0.1 2.1 0.9 0.1 0.1 0.2 1.2 123.2 0.1 55.8 0.3 0.2 0.3 123.3 4.6 0.0 0.1 25.8 4.3 0.2 1.3 2.1 0.0 10.6 9.1 29.9 0.4 0.1 147.4 0.0 0.2 0.0 1.0 0.2 0.1 7.7 0.0 0.0 6.3 6.0 0.6 24.6 0.0 9.5 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.5 30.3 0.0 0.2 0.2 0.3 3.5 0.7 0.0 0.1 0.0 0.2 0.0 0.4 1.4 0.6 0.1 0.2 0.2 75.9 0.3 0.4 0.0 0.6 10.2 1.2 0.2 0.2 0.0 0.2 0.4 0.1 0.1 0.0 0.1 0.2 0.4 7.3 0.1 0.2 0.5 0.8 8.9 0.3 0.1 0.9 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.7 0.2 0.1 0.3 0.1 0.0 0.2 0.2 0.6 0.4 0.2 0.1 0.1 0.4 0.2 0.0 0.2 0.4 0.0 0.0 2.2 0.0 1.0 0.0 18.3 8.9 0.0 0.0 0.5 0.0 0.7 11.5 40.5 104.8 0.0 0.0 0.1 360.1 0.0 92.6 9.8 23.3 8.6 0.3 7.8 0.0 0.0 14.9 0.0 0.2 27.5 75.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 26.9 8.2 0.6 0.0 19.2 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 58.4 163.2 0.0 0.1 8.0 85.5 4.4 9.8 0.0 6.6 0.6 1.5 3.0 0.3 1.4 0.0 0.0 0.8 0.0 48.5 52.4 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.8;intestine: 53.4;salivary gland: 55.8;skin 1: 56.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 208.5;Intestinal goblet cells: 69.4;Paneth cells: 135.8;Proximal enterocytes: 130.9;Undifferentiated cells: 86.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "RT4: 58.5;SK-BR-3: 19.4;T-47d: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved NA NA 72000 "Cluster 6: Non-specific - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favorable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favorable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.6 0.4 5.0 0.5 0.2 9.0 0.7 0.7 7.9 0.4 53.4 44.5 0.4 41.1 53.8 8.5 5.3 0.0 0.5 0.3 39.2 0.4 3.5 0.0 0.5 0.4 0.5 46.8 0.0 0.5 0.0 0.5 6.5 34.0 0.1 55.8 6.4 0.4 56.2 38.4 0.8 0.2 0.1 23.7 0.7 0.4 0.7 0.2 0.0 9.0 18.4 18.8 0.9 3.6 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 6.3 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 58.5 0.2 0.2 0.0 19.4 0.0 0.0 60.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.7 0.7 0.5 0.3 0.5 0.4 0.5 0.2 0.4 0.9 0.1 35.3 6.9 0.0 1.1 4.1 14.7 12.5 5.2 0.0 17.9 11.0 0.2 20.0 38.0 23.9 2.1 0.0 0.3 208.5 21.5 23.8 0.1 7.4 0.3 0.5 6.0 0.0 0.0 38.2 0.0 0.9 24.5 2.6 0.0 0.1 0.4 0.0 0.1 0.0 0.0 69.4 12.2 0.0 1.8 0.2 0.6 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.0 10.6 135.8 0.0 0.0 5.5 130.9 39.5 45.9 0.3 0.0 0.4 2.3 0.0 0.1 30.6 20.9 0.0 1.0 0.0 86.1 26.7 GIPC1 "C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2" ENSG00000123159 "GIPC PDZ domain containing family member 1" O14908 19 14477760-14496149 "Human disease related genes, Predicted intracellular proteins" "Congenital muscular dystrophy, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 345.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 501.1;Pancreatic endocrine cells: 296.7;Paneth cells: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043958, HPA061786" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 11000 "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA043958: AB_10963436, HPA061786: AB_2756319" "unprognostic (2.80e-1)" "unprognostic (1.16e-1)" "unprognostic (8.21e-2)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.18e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (4.82e-2)" "unprognostic (3.53e-2)" "unprognostic (7.72e-2)" "unprognostic (1.04e-2)" "unprognostic (7.17e-3)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" 51.0 54.8 80.0 22.4 91.5 3.3 54.3 88.7 94.4 99.8 64.7 120.2 24.7 53.7 17.6 345.8 48.9 23.4 66.1 74.5 82.1 104.1 58.4 76.3 15.9 89.4 91.4 34.4 43.5 20.8 56.0 28.7 88.1 63.6 41.1 17.9 100.9 31.0 65.1 150.2 45.5 17.5 82.0 37.7 78.7 24.9 91.1 18.6 55.8 23.3 21.0 74.1 140.1 92.3 328.1 148.6 44.7 70.6 40.6 40.7 35.2 119.7 59.8 96.7 87.3 80.3 120.6 4.7 220.3 85.2 64.6 183.8 38.7 100.6 32.6 33.8 69.0 63.9 100.7 79.7 123.7 6.9 75.3 46.7 98.5 58.8 51.3 57.4 66.0 47.2 30.1 54.4 49.9 243.8 21.3 13.3 48.6 182.1 147.8 21.7 37.4 43.7 121.6 281.6 41.8 46.2 67.1 163.2 157.0 23.1 102.5 35.1 115.4 135.7 74.6 191.7 130.1 50.5 70.5 17.3 113.9 51.9 146.2 3.0 0.7 0.1 5.1 1.1 4.7 1.9 5.1 5.1 1.1 0.8 4.2 3.3 0.3 1.5 0.5 3.6 12.0 1.7 80.0 91.5 88.7 94.4 74.5 82.1 89.4 91.4 88.1 82.0 91.1 92.3 30.6 28.9 15.2 22.9 8.3 113.9 77.4 52.1 35.9 69.8 73.6 31.6 14.8 37.1 62.8 82.8 35.5 36.3 19.3 501.1 52.8 167.9 1.1 92.2 30.5 32.4 43.1 1.7 28.8 164.3 77.1 32.6 69.3 76.8 10.2 37.3 23.2 18.0 55.9 75.7 32.2 87.8 42.7 10.8 29.8 2.4 20.5 16.1 58.7 10.3 23.4 73.3 18.6 17.1 71.6 296.7 285.4 25.2 6.8 120.4 36.0 52.7 38.0 46.0 19.7 18.1 44.5 6.4 20.4 107.0 169.8 25.7 22.9 47.7 138.1 199.7 GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 550000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA057790: AB_2683527, HPA062208: AB_2684711" "unprognostic (5.18e-2)" "unprognostic (1.76e-3)" "unprognostic (4.46e-3)" "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (5.29e-2)" "unprognostic (5.84e-3)" "unprognostic (5.50e-2)" "unprognostic (3.41e-2)" "unprognostic (4.46e-3)" "unprognostic (8.13e-2)" "unprognostic (4.12e-3)" "unprognostic (2.33e-2)" "unprognostic (9.33e-2)" "unprognostic (7.78e-2)" "unprognostic (2.14e-3)" 63.4 57.0 14.4 28.5 12.3 0.3 50.1 10.4 14.0 59.3 13.5 68.4 122.0 59.7 27.7 82.0 43.4 59.3 34.5 13.7 19.5 79.2 44.8 34.3 12.0 21.9 29.1 47.9 25.2 54.7 13.1 60.2 16.9 38.3 65.7 6.6 26.6 47.6 12.9 80.4 110.8 73.9 18.6 56.2 42.7 17.7 16.4 15.9 59.8 19.7 22.7 56.5 46.5 18.7 60.5 55.5 58.0 31.5 241.2 207.9 59.5 182.9 237.2 157.9 141.0 26.5 58.2 0.1 75.9 258.0 98.8 44.2 36.6 150.0 275.7 0.5 28.1 1.0 46.0 0.1 96.0 0.1 3.0 125.7 87.8 168.7 221.8 221.1 251.9 0.0 3.6 0.3 175.6 10.2 0.1 0.5 44.1 65.7 68.3 0.3 119.6 0.9 151.8 53.5 13.2 26.8 126.8 52.1 248.4 48.8 26.9 1.1 326.7 182.5 118.8 332.0 114.5 3.0 0.3 0.5 115.3 7.1 252.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 12.3 10.4 14.0 13.7 19.5 21.9 29.1 16.9 18.6 16.4 18.7 49.7 54.5 32.2 54.5 2.1 201.3 78.8 53.3 78.6 2.1 52.4 37.1 26.7 35.8 42.8 58.8 6.2 61.8 0.9 243.1 74.3 96.2 14.6 51.8 20.6 67.0 34.7 5.3 0.5 138.5 105.6 82.6 45.3 49.3 3.8 21.3 76.1 45.6 27.9 3.3 15.3 56.3 30.5 18.2 32.4 16.6 71.4 6.2 78.2 21.5 3.6 3.0 0.0 63.3 1.3 143.7 99.9 75.6 0.2 119.9 227.3 177.9 79.2 18.9 52.6 54.8 71.7 1.8 18.8 83.1 216.8 175.9 4.5 107.1 61.8 109.1 GOLIM4 "GIMPC, GOLPH4, GPP130, P138" ENSG00000173905 "Golgi integral membrane protein 4" O00461 3 168008689-168095924 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 370.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001677, HPA002315" Enhanced Enhanced "Golgi apparatus" NA NA 1000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA001677: AB_1079017, HPA002315: AB_1079018" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (6.27e-2)" "unprognostic (2.11e-1)" "unprognostic (4.76e-2)" "unprognostic (2.44e-1)" "unprognostic (5.17e-2)" "unprognostic (1.39e-1)" "unprognostic (6.46e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.84e-3)" "unprognostic (9.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-3)" 24.8 12.6 25.4 21.4 23.0 9.0 12.9 24.7 32.1 16.8 13.9 53.4 65.8 21.9 8.9 15.7 15.7 28.5 54.6 27.7 34.8 31.3 59.2 29.1 11.3 39.5 29.5 19.9 11.9 12.8 9.6 22.4 40.1 15.2 51.1 53.0 17.3 13.6 32.4 9.3 85.2 26.6 35.1 23.0 24.3 9.0 27.5 6.5 19.0 30.7 9.5 16.8 10.7 33.6 23.7 34.5 47.8 30.4 79.7 58.6 14.5 135.8 72.4 36.3 33.2 38.7 28.4 51.6 159.1 82.4 58.4 42.5 44.4 39.9 54.9 81.3 57.0 83.8 100.2 48.1 32.1 80.5 45.8 61.5 20.9 33.4 32.8 32.2 42.1 0.0 43.7 146.2 41.9 39.2 0.1 21.8 46.9 44.2 36.6 0.1 48.1 72.2 20.6 8.5 42.9 55.5 83.5 25.1 28.4 31.7 30.9 36.1 79.0 114.9 44.2 81.3 110.1 56.4 43.4 109.4 57.1 47.4 52.4 3.2 2.5 10.8 0.6 2.8 0.2 1.2 0.1 0.5 3.3 2.0 0.0 0.2 0.0 5.5 2.3 4.0 0.0 0.7 25.4 23.0 24.7 32.1 27.7 34.8 39.5 29.5 40.1 35.1 27.5 33.6 74.9 48.1 124.8 141.0 11.1 41.4 24.4 18.3 41.5 16.2 21.3 20.6 157.3 67.2 23.3 36.8 37.5 11.4 33.5 184.5 17.6 21.8 1.7 20.6 51.5 70.9 63.3 33.9 18.1 29.6 17.2 119.2 34.1 30.9 58.3 23.3 45.3 178.8 39.1 16.8 84.2 136.5 12.2 50.7 57.5 3.3 39.7 42.2 37.4 38.4 22.0 370.3 14.4 145.8 44.7 23.6 181.2 51.1 28.9 26.0 195.2 31.6 9.2 62.8 46.0 108.2 82.5 5.5 37.6 20.1 35.9 5.5 16.5 20.4 167.6 8.4 GPA33 A33 ENSG00000143167 "Glycoprotein A33" Q99795 1 167052836-167166479 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 215.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 775.5;Intestinal goblet cells: 211.6;Paneth cells: 420.3;Proximal enterocytes: 266.1;Undifferentiated cells: 147.2" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 84.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 24.2;T-reg: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 24.2" "Cell line enriched" "Detected in some" 8 "OE19: 14.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018858, CAB025943" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB025943: , HPA018858: AB_1849909" "unprognostic (2.41e-2)" "unprognostic (1.71e-3)" "unprognostic (1.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (8.39e-4)" "unprognostic (1.55e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-2)" "unprognostic (9.63e-2)" "unprognostic (2.10e-2)" "unprognostic (9.44e-2)" "unprognostic (6.75e-2)" "unprognostic (5.22e-3)" "unprognostic (3.13e-1)" "unprognostic (9.68e-3)" "unprognostic (2.96e-3)" 0.4 0.0 0.0 18.5 0.0 0.7 0.2 0.0 0.2 0.0 0.4 215.9 150.0 0.3 0.0 0.1 0.0 0.2 0.7 0.1 0.1 0.1 0.0 7.1 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 196.2 0.0 0.0 0.4 0.3 0.0 136.9 7.2 0.0 0.9 1.5 0.2 0.2 2.3 0.0 0.1 1.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.3 1.8 14.4 0.0 0.0 0.8 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.8 3.8 1.6 0.2 10.9 5.7 2.7 2.2 24.2 3.5 0.2 0.2 2.6 0.0 19.5 6.8 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.3 775.5 0.0 0.0 3.9 0.0 0.0 0.1 26.1 0.8 0.4 0.0 0.0 0.0 0.5 0.0 4.5 0.0 0.0 0.0 0.5 0.0 0.3 211.6 0.0 1.9 1.3 2.3 0.3 1.8 0.0 0.0 0.3 0.4 0.0 0.0 0.1 0.1 420.3 0.0 0.0 0.0 266.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.1 0.0 3.1 0.0 147.2 0.2 GPATCH1 "ECGP, FLJ10206, FLJ38686, GPATC1" ENSG00000076650 "G-patch domain containing 1" Q9BRR8 19 33080899-33130542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043430, HPA043604, HPA074327" Approved Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Cell Junctions" "HPA043430: AB_10960493, HPA043604: AB_10960499, HPA074327: " "unprognostic (2.38e-2)" "unprognostic (1.71e-2)" "unprognostic (9.95e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.41e-1)" "unprognostic (1.28e-2)" "unprognostic (4.60e-3)" "unprognostic (3.54e-2)" "unprognostic (5.17e-2)" "unprognostic (3.56e-2)" "unprognostic (6.53e-2)" "unprognostic (5.37e-3)" "unprognostic (8.10e-2)" "unprognostic (4.57e-2)" "unprognostic (1.25e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-3)" 3.5 3.1 3.0 3.5 3.2 3.7 4.4 5.1 4.0 4.0 2.0 4.8 5.4 4.5 4.4 4.3 3.9 2.8 3.8 3.1 2.9 4.4 3.4 3.4 4.9 2.8 3.0 7.2 3.8 6.3 2.6 4.2 3.0 4.2 4.5 3.9 4.6 3.4 4.2 5.6 4.6 4.4 2.7 4.3 4.9 4.4 3.3 5.9 4.7 3.2 5.0 3.6 3.6 3.4 8.8 18.2 8.4 9.1 5.5 6.2 7.1 7.8 5.4 11.6 9.7 12.9 7.9 12.3 9.7 6.2 5.5 7.7 10.6 6.4 10.1 21.4 6.6 11.7 6.8 9.8 7.2 20.3 7.6 5.3 7.4 7.9 7.2 5.6 6.6 9.6 12.5 7.7 5.8 11.2 11.8 7.1 5.9 11.5 7.5 11.9 10.6 5.5 5.4 5.4 9.3 6.2 12.3 7.6 4.6 7.2 6.4 14.5 7.5 10.2 7.6 5.6 11.3 6.4 11.1 10.6 6.3 10.3 9.5 23.1 6.4 7.4 6.0 6.6 4.1 6.2 5.6 7.7 6.0 7.0 9.6 6.0 4.7 3.5 3.7 5.3 9.2 5.0 3.0 3.2 5.1 4.0 3.1 2.9 2.8 3.0 3.0 2.7 3.3 3.4 6.5 9.6 7.9 5.9 9.1 6.1 5.0 6.0 10.8 9.7 5.2 4.6 11.8 1.5 9.8 7.3 14.6 10.5 10.7 12.0 15.6 6.8 3.2 5.2 9.4 6.4 4.2 4.2 7.2 4.5 5.2 7.5 10.2 6.8 16.5 10.1 7.9 4.6 4.1 3.3 7.0 7.7 8.2 6.0 5.2 2.1 10.2 5.8 8.8 2.8 5.8 7.1 16.5 5.5 7.0 9.0 8.7 8.2 5.5 3.3 6.8 6.6 10.3 11.9 0.0 8.0 7.3 19.5 14.8 6.5 3.7 5.5 9.1 7.0 6.5 3.4 GPD1L KIAA0089 ENSG00000152642 "Glycerol-3-phosphate dehydrogenase 1 like" Q8N335 3 32105689-32168709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.4;tongue: 253.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 154.1;Distal enterocytes: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 136.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.23e-1)" "unprognostic (3.12e-2)" "prognostic favorable (7.05e-4)" "unprognostic (2.63e-1)" "unprognostic (9.67e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (1.35e-5)" "prognostic favorable (5.71e-5)" "unprognostic (2.49e-2)" "unprognostic (1.74e-1)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.33e-15)" "unprognostic (1.50e-1)" "unprognostic (1.99e-1)" "unprognostic (2.31e-3)" "unprognostic (5.51e-3)" 39.0 44.7 18.2 8.3 20.1 6.9 30.6 17.2 21.2 22.8 27.1 40.1 26.5 11.6 9.8 40.9 19.1 9.2 124.8 21.2 20.5 34.2 2.8 31.3 9.0 19.2 18.6 16.6 21.6 32.8 5.9 20.8 19.3 59.9 36.7 9.8 22.0 41.2 158.4 10.3 29.0 16.6 20.5 12.8 29.7 6.1 18.3 6.8 40.3 253.1 10.2 31.0 12.9 21.9 11.1 10.0 3.5 15.3 49.3 11.9 136.1 8.8 3.1 9.2 7.1 10.7 5.2 19.4 13.2 6.2 11.3 12.6 23.4 9.3 11.6 8.3 21.4 11.3 13.2 16.8 12.4 29.4 39.3 35.5 12.1 8.9 12.5 9.4 16.3 15.7 8.0 6.1 7.3 15.1 12.6 11.0 2.1 27.6 44.8 23.1 15.7 40.0 14.6 66.8 15.1 15.0 6.7 61.1 25.0 4.8 38.7 14.1 8.6 10.5 4.9 16.3 23.6 4.3 2.0 19.3 24.0 22.3 6.0 0.5 2.8 5.7 3.3 3.2 8.0 1.5 4.1 4.0 5.6 1.2 2.5 3.7 1.4 7.4 2.1 4.4 8.8 2.8 18.2 20.1 17.2 21.2 21.2 20.5 19.2 18.6 19.3 20.5 18.3 21.9 10.2 28.9 41.8 1.3 4.1 4.6 5.3 3.5 8.6 4.1 20.3 10.7 154.1 2.8 18.6 9.2 2.1 36.4 10.8 75.2 39.2 2.0 8.0 5.3 4.4 10.5 7.8 6.9 23.1 3.7 6.1 10.5 17.3 9.2 39.3 9.8 13.2 0.7 10.0 1.7 23.7 21.3 26.4 6.3 5.7 20.7 5.9 4.4 8.8 24.4 2.3 32.9 7.2 3.0 11.1 4.3 21.6 12.8 8.7 13.8 33.9 18.4 15.0 3.9 0.0 8.0 8.7 0.8 2.1 32.3 7.0 27.1 10.4 3.3 26.9 8.5 GPN2 "ATPBD1B, FLJ10349" ENSG00000142751 "GPN-loop GTPase 2" Q9H9Y4 1 26876132-26890283 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028059 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA028059: AB_10612113" "unprognostic (2.14e-1)" "unprognostic (4.44e-2)" "unprognostic (5.44e-2)" "unprognostic (1.19e-2)" "unprognostic (1.71e-2)" "unprognostic (9.09e-3)" "prognostic unfavorable (3.56e-8)" "unprognostic (1.17e-1)" "unprognostic (9.68e-3)" "unprognostic (1.75e-2)" "unprognostic (2.75e-3)" "unprognostic (1.18e-2)" "unprognostic (9.99e-2)" "unprognostic (1.29e-1)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (1.63e-2)" 15.2 22.2 10.9 11.9 10.3 21.6 14.5 11.9 12.1 13.6 9.3 16.3 15.4 14.4 16.0 21.1 12.0 12.0 19.3 10.1 10.7 15.9 19.7 13.1 15.7 11.3 9.9 12.4 14.9 17.4 13.8 13.1 10.4 16.6 17.2 11.9 14.0 12.3 23.2 19.1 15.5 15.4 9.7 17.2 15.4 13.0 11.0 15.3 12.7 13.3 19.9 16.7 14.9 11.6 35.6 16.7 20.2 19.4 21.2 20.3 15.7 26.1 35.0 40.3 41.9 27.4 38.4 17.0 33.7 37.5 32.0 34.3 43.7 60.9 51.9 20.1 28.7 29.6 30.7 29.8 36.3 39.6 30.8 25.4 23.3 65.3 46.1 23.1 40.1 20.7 30.1 19.3 34.9 29.6 19.8 35.0 36.8 38.2 35.2 26.6 29.9 28.6 30.3 19.8 27.2 18.5 34.9 23.0 43.0 21.5 27.5 16.1 24.3 29.8 31.0 25.6 27.3 39.6 21.9 25.6 23.1 36.1 26.9 7.5 29.1 31.3 23.6 33.5 26.5 30.0 22.9 22.7 27.2 31.0 17.2 16.6 9.2 21.4 35.0 28.0 29.8 16.5 10.9 10.3 11.9 12.1 10.1 10.7 11.3 9.9 10.4 9.7 11.0 11.6 9.4 16.0 11.8 1.6 12.6 18.7 15.7 20.1 9.1 9.6 9.3 6.5 4.1 24.3 16.4 16.5 8.4 35.4 9.8 26.5 13.7 22.1 13.8 12.1 10.0 12.2 18.5 11.1 3.8 19.1 26.3 12.6 14.8 14.6 17.7 13.2 12.1 14.6 22.3 13.5 3.3 17.2 4.1 13.9 9.5 6.1 9.6 11.6 8.8 2.8 23.2 7.5 5.2 3.5 4.0 19.0 20.4 11.7 9.1 20.4 25.9 17.2 8.5 9.6 6.6 10.9 11.1 19.8 12.6 11.7 22.4 43.2 11.4 12.2 17.8 27.4 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GPR35 ENSG00000178623 "G protein-coupled receptor 35" Q9HC97 2 240605430-240631259 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 82.8;granulocytes: 38.1;Intestinal goblet cells: 32.2;Langerhans cells: 35.7;Paneth cells: 38.6;Proximal enterocytes: 99.3;Undifferentiated cells: 31.1" "Group enriched" "Detected in many" 4 "colorectal cancer: 20.7;pancreatic cancer: 6.9;stomach cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 36.3;eosinophil: 40.1;intermediate monocyte: 51.7;myeloid DC: 32.5;non-classical monocyte: 14.5" "Group enriched" "Detected in many" 16 "dendritic cells: 32.5;granulocytes: 40.1;monocytes: 51.7" "Cell line enhanced" "Detected in some" "CACO-2: 20.7;CAPAN-2: 51.2;HDLM-2: 17.6;Hep G2: 33.6;HMC-1: 31.5;NB-4: 16.4;OE19: 38.7;U-937: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.53e-1)" "unprognostic (5.99e-2)" "unprognostic (3.94e-3)" "unprognostic (2.71e-2)" "prognostic unfavorable (5.86e-4)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.98e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (7.03e-3)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-3)" 2.1 0.8 5.5 4.3 4.8 4.5 2.4 4.4 5.8 4.7 2.9 28.3 41.0 3.8 1.2 2.5 7.3 5.9 3.3 5.4 4.6 5.4 1.6 3.4 1.7 5.5 4.6 5.4 1.8 0.2 6.6 0.5 5.6 4.5 16.6 2.0 1.6 1.0 7.0 2.6 38.2 1.9 4.4 10.3 15.8 5.4 5.4 1.8 3.0 0.3 1.0 2.9 2.7 4.6 0.1 0.5 0.3 1.1 0.9 0.0 0.4 0.1 0.3 0.1 0.3 20.7 51.2 0.3 0.2 0.2 0.7 0.5 0.0 0.0 0.1 17.6 0.7 8.7 0.5 33.6 0.4 0.4 31.5 0.2 0.1 0.6 0.3 0.4 0.1 1.3 0.3 2.9 0.0 0.7 0.4 16.4 0.8 38.7 0.2 1.9 0.1 0.5 0.2 0.2 2.0 0.8 0.0 0.1 0.4 0.5 0.2 5.9 0.7 0.2 0.2 1.4 0.1 3.5 1.6 0.2 0.1 18.2 0.4 0.1 36.3 40.1 1.5 51.7 2.6 0.0 0.8 0.8 32.5 0.1 0.5 1.2 0.4 0.8 14.5 0.6 0.3 13.6 5.5 4.8 4.4 5.8 5.4 4.6 5.5 4.6 5.6 4.4 5.4 4.6 0.6 0.0 4.4 7.8 1.6 2.0 0.1 0.2 0.0 1.4 0.4 0.4 1.2 2.8 0.3 1.8 0.0 0.1 5.1 82.8 0.0 0.9 0.1 3.1 0.6 0.4 6.7 0.0 1.9 3.3 0.0 0.3 25.0 3.1 38.1 0.8 0.4 0.3 10.7 1.7 2.1 32.2 0.0 8.5 35.7 0.0 0.3 22.3 0.0 1.9 9.7 0.2 1.0 0.5 1.5 14.1 38.6 1.2 1.2 0.0 99.3 3.7 0.9 2.5 0.0 0.2 0.9 1.2 0.6 0.1 1.1 0.3 8.0 0.1 31.1 0.3 GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 179.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.9;Hepatocytes: 237.3;Paneth cells: 88.4;Proximal enterocytes: 139.7;Proximal tubular cells: 164.9" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;Karpas-707: 2.8;U-266/70: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favorable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" 22.6 2.4 2.2 4.6 1.9 2.3 12.5 3.3 4.7 0.7 3.5 36.0 18.3 0.5 0.4 2.4 1.3 2.4 40.3 2.1 0.4 13.9 179.6 0.4 0.3 0.8 0.5 1.1 10.3 1.4 2.9 0.1 0.6 1.8 5.8 0.6 14.6 1.2 50.1 17.1 18.0 0.4 0.2 0.6 15.0 2.6 0.9 0.0 0.9 24.3 0.2 0.6 1.3 0.9 0.2 0.8 0.2 0.5 0.4 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.9 0.4 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.7 1.3 0.3 1.5 2.5 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.2 2.8 0.0 1.3 0.4 0.4 0.3 0.6 0.5 0.5 0.1 1.5 0.0 0.9 0.5 0.8 0.2 0.7 0.1 0.1 1.9 0.1 0.2 0.1 0.6 0.7 0.1 2.9 0.2 0.2 0.4 0.9 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.2 1.9 3.3 4.7 2.1 0.4 0.8 0.5 0.6 0.2 0.9 0.9 0.2 0.0 0.0 14.4 5.3 1.7 1.3 1.2 0.6 0.9 14.1 4.6 8.5 34.3 1.8 7.3 0.0 0.0 0.4 176.9 21.5 1.1 16.5 0.5 0.4 1.1 2.4 43.2 0.8 2.4 3.3 0.3 51.0 0.7 8.9 0.3 14.3 237.3 0.1 3.3 0.5 30.4 0.0 14.4 2.1 48.1 0.6 1.2 1.8 1.0 0.1 15.6 0.0 2.0 0.0 1.3 88.4 0.4 0.1 1.2 139.7 164.9 0.5 2.0 0.0 2.0 0.4 1.0 0.6 2.4 4.5 0.0 1.8 0.4 62.1 1.6 GPX2 GSHPX-GI ENSG00000176153 "Glutathione peroxidase 2" P18283 14 64939152-64942905 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 497.7;intestine: 453.8;liver: 634.0;stomach 1: 374.6;urinary bladder: 350.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 386.1;Distal enterocytes: 436.6;Gastric mucus-secreting cells: 912.3;Hepatocytes: 753.4;Intestinal goblet cells: 438.6;Paneth cells: 463.0;Undifferentiated cells: 776.8;Urothelial cells: 1062.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 493.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 4748.8" "Region enhanced" "Detected in single" "pons and medulla: 1.2" "Low region specificity" "Detected in some" HPA003545 Enhanced Approved Nucleoplasm,Cytosol NA NA 82000 "Cluster 48: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA003545: AB_10962695" "unprognostic (3.54e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-3)" "unprognostic (4.75e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.96e-2)" "unprognostic (2.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (4.39e-2)" "unprognostic (3.39e-2)" "unprognostic (6.66e-4)" "unprognostic (1.73e-2)" 1.9 0.2 0.1 53.8 0.3 0.3 5.3 0.5 0.3 23.5 0.1 333.5 96.7 0.7 1.7 187.7 4.9 497.7 0.3 0.2 0.5 30.6 634.0 2.6 0.1 0.4 0.2 0.2 24.5 0.0 1.2 0.2 0.4 43.3 453.8 0.0 71.8 24.9 0.3 25.4 175.7 9.7 0.1 0.6 374.6 2.5 0.3 3.3 0.5 0.0 1.2 350.5 108.2 0.7 0.0 1152.6 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 36.9 9.6 0.0 6.0 0.0 1.9 303.7 0.6 4.8 0.0 0.2 0.1 0.1 1.1 1048.6 0.0 0.1 0.4 0.0 9.7 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 5.6 0.6 0.3 1.3 4748.8 0.2 0.5 0.2 0.2 0.1 727.5 324.2 0.2 0.1 13.4 0.0 0.6 0.5 0.0 0.0 0.0 0.8 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.3 0.2 0.5 0.4 0.2 0.4 0.1 0.3 0.7 0.1 0.0 0.0 0.3 6.9 9.9 169.4 104.5 42.1 0.2 0.6 4.1 0.4 386.1 17.1 23.9 0.0 0.1 0.0 436.6 11.7 272.8 13.8 3.8 0.5 3.5 115.2 50.8 0.2 260.6 0.1 2.1 912.3 2.8 13.4 0.1 17.5 753.4 0.0 0.0 0.2 438.6 36.7 26.1 0.8 66.6 0.9 3.5 0.0 1.9 3.2 0.0 0.0 0.0 0.4 163.7 463.0 0.0 2.4 100.7 68.1 31.4 9.0 0.7 0.0 0.0 3.6 0.4 0.0 315.5 9.7 0.0 5.9 0.1 776.8 1062.0 GSDMD "DF5L, FLJ12150, GSDMDC1" ENSG00000104518 "Gasdermin D" P57764 8 143553207-143563062 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 226.7;Proximal enterocytes: 297.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004656, HPA044487" Uncertain Supported Nucleoplasm "Intracellular and membrane" NA NA 11000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB004656: AB_426076, HPA044487: AB_2678957" "unprognostic (1.11e-2)" "unprognostic (8.44e-2)" "unprognostic (6.72e-2)" "unprognostic (4.00e-2)" "unprognostic (4.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (7.20e-2)" "unprognostic (6.36e-2)" "unprognostic (4.66e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (8.51e-3)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (6.77e-3)" 43.1 36.0 6.5 34.1 6.7 39.4 41.5 6.5 9.0 42.9 11.1 48.4 51.3 36.7 9.1 22.5 41.5 15.7 24.6 6.2 6.4 50.6 88.8 54.8 42.3 7.7 7.2 39.5 35.1 19.2 18.3 16.5 7.2 39.0 13.6 1.0 32.5 15.1 11.0 16.8 60.3 12.4 7.1 120.1 37.9 7.3 7.0 24.4 46.4 6.1 16.1 35.8 31.7 7.1 40.8 18.4 0.3 0.1 13.4 14.7 23.8 13.8 36.4 44.0 47.4 3.1 54.6 14.5 21.9 21.1 19.6 12.5 0.7 31.1 11.1 43.8 2.8 23.2 5.4 22.6 17.8 4.2 1.0 35.5 2.6 16.1 9.4 14.5 34.1 34.2 1.4 49.1 2.3 0.8 87.5 7.1 0.3 27.3 67.6 30.2 1.5 48.7 22.5 39.9 0.5 0.6 44.2 39.8 43.4 5.6 69.7 24.8 13.3 0.2 44.6 3.2 22.1 16.5 22.4 0.4 26.5 19.6 21.8 65.4 44.7 45.9 55.0 73.2 44.8 39.9 48.6 53.7 40.7 31.1 33.8 40.4 46.2 41.1 69.1 29.1 71.1 46.8 6.5 6.7 6.5 9.0 6.2 6.4 7.7 7.2 7.2 7.1 7.0 7.1 91.1 12.8 29.1 6.8 39.8 10.8 47.1 55.7 23.9 0.2 31.6 30.5 12.2 47.1 37.5 31.3 0.0 62.0 54.6 226.7 60.7 68.3 2.2 33.8 20.0 57.0 39.6 14.9 0.1 92.7 98.1 34.0 68.8 27.2 27.3 171.1 75.3 72.3 63.1 0.0 0.1 114.8 30.5 50.1 18.4 7.0 23.6 52.5 17.8 7.5 74.4 28.9 81.4 0.5 0.1 50.2 181.1 22.6 41.1 34.6 297.7 121.8 43.1 1.7 59.2 24.0 34.4 1.4 12.3 13.8 8.9 41.7 61.5 24.2 131.8 45.9 HDAC1 "GON-10, HD1, KDAC1, RPD3L1" ENSG00000116478 "Histone deacetylase 1" Q13547 1 32292083-32333635 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005017, HPA029693, CAB068191" Enhanced Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB005017: AB_2248344, CAB068191: AB_2665664, HPA029693: AB_10601659" "unprognostic (2.51e-2)" "unprognostic (9.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.57e-2)" "unprognostic (5.02e-2)" "unprognostic (3.47e-2)" "unprognostic (7.06e-2)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (6.86e-2)" "unprognostic (3.78e-1)" "unprognostic (7.16e-2)" "unprognostic (1.72e-1)" 31.4 42.8 20.8 76.7 22.1 59.3 56.0 21.9 28.0 56.6 20.3 119.5 74.5 48.1 51.4 81.3 56.8 55.4 29.0 20.4 21.9 47.9 41.7 41.2 119.7 23.3 21.8 65.7 40.0 62.3 31.6 53.0 23.1 57.6 108.3 18.9 52.1 57.2 15.3 38.0 80.8 46.8 21.8 61.7 84.1 36.2 22.0 103.9 78.4 17.5 123.9 63.7 51.7 23.4 152.5 90.6 57.4 114.7 32.9 39.0 118.7 105.1 117.1 138.0 126.6 168.0 266.3 233.4 190.3 116.9 140.2 173.1 178.1 143.1 151.5 219.3 176.8 161.3 105.7 130.1 77.4 288.1 223.4 70.7 77.0 107.1 70.3 107.7 106.1 298.5 215.2 90.1 61.6 115.7 331.6 161.4 133.2 180.2 229.6 225.0 136.0 104.0 149.5 216.1 44.7 56.6 176.0 117.0 227.9 224.0 137.9 220.6 123.8 91.3 106.2 28.5 261.1 54.4 124.9 319.2 75.3 235.8 121.4 147.5 87.7 200.1 130.0 115.9 107.5 151.6 126.2 140.6 103.0 142.0 143.7 133.6 63.7 144.2 156.4 64.9 142.0 204.6 20.8 22.1 21.9 28.0 20.4 21.9 23.3 21.8 23.1 21.8 22.0 23.4 45.3 25.6 45.4 25.5 82.7 24.9 57.4 99.1 38.7 15.1 35.1 29.1 22.1 61.5 73.4 68.0 16.7 93.1 64.0 142.4 95.9 75.7 20.2 33.7 39.8 56.2 86.3 60.8 1.9 73.6 110.9 25.8 65.2 39.5 30.4 23.6 63.5 28.1 43.6 11.8 8.8 122.8 52.9 38.2 19.0 8.7 41.0 35.0 28.4 16.9 52.7 34.2 69.0 14.6 19.4 92.5 141.5 44.4 38.4 28.5 57.0 30.0 67.3 14.6 59.2 22.8 38.1 72.5 69.8 60.2 25.4 93.4 73.6 102.6 136.0 55.8 HDHD3 "C9orf158, MGC12904" ENSG00000119431 "Haloacid dehalogenase like hydrolase domain containing 3" Q9BSH5 9 113373419-113376999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 214.0;Exocrine glandular cells: 156.4;Paneth cells: 208.6;Proximal enterocytes: 254.0;Proximal tubular cells: 275.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020427, HPA024158, HPA024585" Enhanced Enhanced Nucleoli,Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli Vesicles "HPA020427: AB_1850561, HPA024158: AB_1850563, HPA024585: AB_1850565" "unprognostic (1.30e-1)" "prognostic favorable (2.72e-4)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (8.24e-3)" "unprognostic (1.57e-2)" "unprognostic (6.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (5.87e-2)" "prognostic favorable (3.54e-7)" "unprognostic (2.16e-2)" "unprognostic (1.84e-1)" "unprognostic (4.68e-1)" "unprognostic (1.19e-3)" 12.2 156.4 16.8 11.1 18.0 8.4 19.5 16.2 19.3 19.9 14.5 59.7 82.9 13.4 14.9 42.1 16.5 17.8 22.4 15.8 17.7 56.3 122.8 10.2 10.2 15.7 17.0 19.9 53.0 68.4 23.1 5.0 16.2 30.4 35.9 8.0 52.2 16.1 8.8 28.3 68.5 7.7 15.7 17.6 50.1 7.0 18.5 6.7 38.7 5.7 7.6 17.6 21.1 15.5 7.4 20.8 4.4 12.3 10.7 4.7 37.0 5.4 10.1 8.6 9.3 38.3 36.1 16.2 6.6 3.0 17.0 28.3 7.0 8.3 2.9 22.9 16.1 22.4 12.5 24.1 12.5 1.4 16.6 7.4 17.4 7.0 19.7 9.9 4.5 14.9 18.0 4.0 4.1 48.3 10.4 6.5 9.9 73.7 16.1 8.5 0.0 13.2 11.0 15.4 11.1 7.0 9.3 39.4 14.0 9.5 24.8 4.7 4.5 1.7 0.1 1.4 1.9 9.7 20.2 6.8 2.1 0.1 1.3 0.2 3.7 8.2 12.4 2.1 14.0 14.8 14.2 11.5 6.1 16.6 14.5 11.1 2.4 8.2 0.2 14.1 17.1 8.5 16.8 18.0 16.2 19.3 15.8 17.7 15.7 17.0 16.2 15.7 18.5 15.5 4.1 9.6 10.1 24.5 19.7 9.9 20.6 26.6 10.8 10.3 38.6 31.2 15.8 80.1 32.6 23.9 10.4 29.4 11.7 214.0 86.1 84.8 0.2 20.9 6.4 9.4 40.3 15.4 9.2 156.4 16.5 8.6 112.7 22.3 7.6 122.4 9.7 85.4 20.6 1.7 10.4 80.4 28.5 6.5 3.7 2.0 14.3 6.9 10.6 6.5 13.7 12.1 15.5 5.5 4.9 104.8 208.6 9.1 9.3 23.7 254.0 275.1 33.3 13.8 6.6 5.5 11.1 0.3 6.0 42.9 14.6 31.6 14.0 26.0 94.6 51.4 HEATR5A "C14orf125, DKFZP434I1735" ENSG00000129493 "HEAT repeat containing 5A" Q86XA9 14 31291788-31420550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 67.8;Oligodendrocytes: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 120.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 120.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049539 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA049539: AB_2680809" "unprognostic (2.63e-1)" "unprognostic (2.24e-1)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (5.47e-3)" "unprognostic (3.97e-2)" "unprognostic (9.37e-2)" "unprognostic (8.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "prognostic favorable (1.11e-6)" "unprognostic (1.00e-1)" "unprognostic (5.93e-2)" "unprognostic (2.83e-2)" "unprognostic (6.00e-2)" 8.6 11.1 8.9 8.9 12.5 7.0 8.0 11.0 8.8 9.6 9.7 14.1 10.3 7.3 5.8 10.0 8.9 7.4 16.3 8.2 12.9 10.2 8.7 8.9 5.7 13.8 11.6 6.2 4.8 9.1 7.5 12.1 15.5 5.8 11.4 7.4 8.0 5.7 12.1 4.2 12.0 10.3 10.1 8.0 7.5 8.2 10.5 3.5 7.6 20.3 6.7 10.9 6.6 18.5 28.3 43.3 12.2 15.7 29.0 27.3 25.3 33.6 28.3 18.0 18.3 17.4 21.1 15.1 31.4 50.7 10.8 18.6 23.2 10.3 25.5 11.5 21.4 11.4 56.5 73.8 16.9 21.9 15.8 12.8 5.5 15.4 14.6 14.1 22.8 6.9 23.4 15.2 21.0 25.2 8.2 9.4 9.3 17.8 25.2 4.7 24.1 8.6 11.9 17.5 5.1 15.3 77.2 35.3 78.4 17.0 20.0 6.2 35.4 13.1 19.6 22.5 13.6 14.9 42.3 23.8 3.9 12.0 19.5 120.4 11.8 47.3 2.7 11.7 1.6 4.7 1.9 2.4 8.2 3.6 1.6 2.9 38.4 3.7 18.1 3.7 2.0 4.6 8.9 12.5 11.0 8.8 8.2 12.9 13.8 11.6 15.5 10.1 10.5 18.5 7.8 28.9 20.2 58.4 7.5 5.9 2.4 6.3 5.2 12.1 9.9 5.5 17.0 5.7 15.5 18.4 14.6 13.1 2.7 33.5 1.9 11.7 3.5 16.3 9.0 8.7 6.7 2.5 27.1 11.7 10.8 13.1 9.7 7.4 11.4 6.9 10.4 14.8 10.6 1.7 38.8 13.5 10.2 14.8 10.8 1.3 12.2 13.6 10.6 42.2 15.1 19.2 1.0 67.8 96.6 17.6 22.4 11.7 10.1 6.3 17.3 8.9 21.8 9.3 0.0 18.1 9.6 21.7 13.2 10.0 7.2 18.1 5.9 11.4 13.1 4.9 HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162549-66268867 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.9;smooth muscle: 82.7" "Cell type enhanced" "Detected in many" "Astrocytes: 78.0;Distal enterocytes: 211.0;Intestinal goblet cells: 95.6;Paneth cells: 96.9;Proximal enterocytes: 156.2;Undifferentiated cells: 72.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 28.5;HEL: 25.4;HSkMC: 36.0;K-562: 72.5;LHCN-M2: 28.5;SuSa: 68.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" 8.2 19.1 18.2 14.7 25.0 0.0 8.3 20.8 19.2 23.8 8.7 81.9 79.0 34.7 14.4 11.9 14.2 38.7 36.0 16.7 21.2 8.1 3.5 12.3 3.6 22.3 24.4 22.1 2.3 1.4 3.7 1.3 20.4 24.3 77.6 15.0 7.6 31.8 0.8 4.8 81.6 82.7 18.8 11.1 12.4 3.5 21.7 1.3 5.1 3.2 2.6 19.5 10.1 21.0 0.0 0.0 28.5 2.3 0.0 0.1 0.8 7.3 0.4 0.0 0.0 17.4 0.0 0.0 0.1 15.1 0.0 0.0 0.0 0.0 0.0 8.3 0.0 25.4 0.0 0.0 0.3 0.2 0.1 36.0 0.0 0.0 0.0 9.9 0.0 0.0 72.5 0.6 28.5 0.0 0.0 0.6 14.1 4.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 68.6 0.0 0.0 0.7 16.2 1.2 0.1 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 25.0 20.8 19.2 16.7 21.2 22.3 24.4 20.4 18.8 21.7 21.0 2.5 0.0 0.0 78.0 0.5 0.9 0.0 0.0 0.0 1.0 0.9 6.0 24.1 0.0 0.0 0.0 0.0 0.0 0.1 211.0 0.0 0.3 0.6 1.3 15.1 4.1 40.8 0.0 0.3 1.1 0.0 12.6 0.0 1.2 0.0 1.1 6.4 0.0 0.2 0.0 2.9 95.6 0.0 0.0 1.9 1.5 11.5 0.3 0.0 6.5 0.0 26.1 0.0 3.5 36.2 5.0 96.9 29.7 0.0 0.3 156.2 0.0 0.7 1.3 6.6 4.4 9.8 0.0 0.3 0.3 0.6 0.0 0.5 6.9 72.4 0.2 HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 174.9;Oligodendrocytes: 209.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 201.4;fHDF/TERT166: 226.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045453, HPA070301" Uncertain Supported "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoli fibrillar center" "HPA045453: AB_10961917, HPA070301: AB_2686247" "unprognostic (3.66e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (4.23e-2)" "unprognostic (3.51e-2)" "unprognostic (1.01e-3)" "unprognostic (3.54e-1)" "unprognostic (8.57e-2)" "unprognostic (4.94e-3)" "unprognostic (2.25e-2)" "prognostic unfavorable (3.86e-5)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.98e-1)" "unprognostic (2.31e-2)" 13.9 19.6 18.2 14.4 18.9 10.9 14.3 19.5 23.5 15.2 15.3 14.1 13.8 14.9 14.0 14.5 13.4 13.3 13.6 20.6 22.4 13.7 16.6 13.9 21.0 19.4 19.7 15.3 11.1 12.0 14.1 16.5 19.4 12.2 15.9 13.9 11.5 11.4 13.5 13.4 14.6 15.6 18.1 18.2 11.6 14.2 21.1 15.2 13.1 12.3 19.4 16.2 14.3 26.7 75.4 30.4 16.7 28.5 47.5 63.9 15.5 201.4 125.5 75.5 47.6 17.5 35.3 29.7 14.3 226.7 40.6 40.9 21.1 28.9 102.0 17.6 9.2 13.7 51.3 12.2 22.6 17.3 21.3 30.2 33.8 39.3 34.4 89.1 47.5 15.0 14.9 14.3 117.4 35.2 11.3 19.9 9.9 15.8 49.0 15.3 7.6 8.2 32.3 23.7 8.7 9.4 66.1 26.4 26.5 37.6 15.4 20.1 65.0 38.2 17.5 94.7 31.9 8.7 11.2 17.8 67.7 32.3 13.6 10.8 5.0 6.6 3.9 4.1 5.0 3.4 4.1 4.5 5.7 3.4 4.1 4.2 6.7 5.2 4.1 1.6 5.6 3.7 18.2 18.9 19.5 23.5 20.6 22.4 19.4 19.7 19.4 18.1 21.1 26.7 29.8 48.1 29.3 127.0 41.0 50.3 33.7 27.2 26.2 50.1 29.1 16.6 23.0 14.3 24.1 18.4 43.8 29.3 38.7 78.7 7.9 19.5 66.4 44.3 45.4 30.9 22.1 32.4 170.2 12.2 40.8 30.3 34.1 70.9 30.4 31.3 28.5 24.5 23.6 53.8 148.8 29.9 26.4 42.9 23.3 47.4 26.8 30.9 17.8 149.9 36.0 18.9 40.2 174.9 209.2 38.6 52.3 19.2 17.4 42.6 37.8 24.9 25.5 45.8 6.6 33.2 28.1 25.2 12.4 23.4 60.9 15.6 40.9 38.5 21.9 48.5 HES1 "bHLHb39, FLJ20408, HES-1, HRY" ENSG00000114315 "Hes family bHLH transcription factor 1" Q14469 3 194136148-194138732 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 850.6;Muller glia cells: 1146.0;Paneth cells: 1137.2;Undifferentiated cells: 882.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "eosinophil: 15.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.6" "Cell line enhanced" "Detected in many" "hTCEpi: 94.1;OE19: 95.8;SK-BR-3: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066929 Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA066929: AB_2732753" "unprognostic (1.79e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-2)" "unprognostic (4.44e-2)" "unprognostic (1.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.01e-2)" "unprognostic (1.05e-1)" "unprognostic (4.64e-1)" "unprognostic (2.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.40e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.74e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.04e-5)" 64.2 32.2 13.6 7.9 14.9 0.9 87.0 12.5 15.0 66.0 11.8 44.1 31.2 22.5 9.0 127.8 22.4 17.7 65.6 14.7 16.8 87.3 68.7 47.1 7.0 15.3 17.4 25.3 34.8 22.6 42.7 27.5 13.5 90.1 35.7 66.5 79.9 31.5 69.9 184.5 23.9 9.8 13.5 23.4 42.1 12.8 14.5 11.9 93.2 22.4 11.8 59.8 136.6 11.6 9.3 2.6 20.8 27.1 6.1 0.0 5.2 4.3 12.2 0.9 0.5 36.4 26.1 1.3 74.6 1.6 12.6 51.4 3.9 24.2 0.3 7.7 44.0 33.1 3.5 9.4 0.1 0.2 30.1 2.2 94.1 0.8 10.9 14.3 28.6 1.7 16.1 1.2 0.0 43.9 47.5 45.7 19.4 95.8 17.8 0.1 1.5 1.0 28.0 71.2 1.2 1.6 21.0 78.9 38.9 23.6 22.2 2.6 22.3 2.3 21.8 0.3 31.3 0.2 0.1 0.2 1.6 0.1 43.7 0.0 0.0 15.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 13.6 14.9 12.5 15.0 14.7 16.8 15.3 17.4 13.5 13.5 14.5 11.6 684.0 25.6 96.0 70.2 54.2 122.9 498.5 736.7 159.4 15.9 352.0 164.1 128.8 517.6 355.1 196.8 16.7 41.1 4.7 696.8 189.8 268.9 2.2 231.9 37.6 401.8 160.1 19.2 1.2 199.1 6.0 274.1 105.0 257.4 303.4 16.1 850.6 163.1 24.4 10.1 0.4 579.7 213.6 95.3 76.2 8.7 58.7 74.6 80.0 5.6 22.8 1146.0 0.0 4.5 0.1 227.1 1137.2 18.8 5.0 231.1 297.5 126.6 190.2 54.9 164.3 76.8 291.7 1.2 13.2 367.8 296.5 209.2 24.1 31.4 882.7 358.1 HHLA2 "B7-H5, B7-H7, B7H7, B7y" ENSG00000114455 "HERV-H LTR-associating 2" Q9UM44 3 108296490-108378285 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 129.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 274.7;Paneth cells: 64.2;Proximal enterocytes: 186.8" "Group enriched" "Detected in many" 12 "colorectal cancer: 9.2;lung cancer: 5.0;pancreatic cancer: 5.1;renal cancer: 16.6;stomach cancer: 6.2" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 1.7;HDLM-2: 4.0;Karpas-707: 2.8" "Low region specificity" "Detected in all" HPA055478 Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055478: AB_2682830" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (1.59e-2)" "unprognostic (8.14e-5)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-1)" "unprognostic (2.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.66e-2)" 0.4 0.2 0.5 5.6 0.4 1.1 0.2 0.7 1.3 0.0 0.0 87.9 86.8 0.3 0.8 0.5 3.7 29.2 0.2 0.6 0.7 7.6 0.1 5.7 0.6 0.7 0.3 0.1 2.9 0.1 0.2 0.1 0.6 0.2 83.0 1.2 0.2 0.3 0.5 0.3 129.9 2.0 0.2 0.3 9.4 3.3 0.6 0.4 0.2 0.0 0.3 0.0 0.0 0.8 0.2 0.3 0.2 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 1.7 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.0 0.0 4.0 0.1 0.1 1.4 0.2 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.8 0.0 0.2 0.4 1.5 0.5 0.2 0.3 0.3 0.1 0.8 0.0 0.1 0.7 0.7 0.7 0.0 0.1 0.5 0.1 0.2 0.1 0.1 0.7 0.2 0.2 1.3 0.7 0.3 0.0 0.4 0.1 0.5 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.1 1.8 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.2 0.5 0.4 0.7 1.3 0.6 0.7 0.7 0.3 0.6 0.2 0.6 0.8 0.0 0.0 2.0 0.7 0.4 0.0 0.1 0.7 0.0 0.0 0.7 0.3 0.2 27.1 1.6 0.0 0.0 0.0 0.0 274.7 0.0 8.5 3.3 3.2 0.0 0.3 1.8 0.0 1.3 37.6 0.1 0.3 2.6 0.1 2.5 0.0 0.0 0.0 0.1 0.0 0.5 12.5 2.0 0.0 0.7 4.2 0.3 0.3 0.0 0.0 1.1 0.0 0.0 0.5 0.9 35.7 64.2 0.0 0.0 0.1 186.8 20.4 19.4 0.0 0.0 0.1 0.1 0.7 0.3 0.0 0.0 0.1 0.5 0.0 17.7 0.1 HIGD1A "DKFZP564K247, HIG1, RCF1A" ENSG00000181061 "HIG1 hypoxia inducible domain family member 1A" Q9Y241 3 42782908-42804490 "Predicted membrane proteins" "Electron transport, Respiratory chain, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 638.8;Distal tubular cells: 632.0;Paneth cells: 610.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 509.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043336 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA043336: AB_10795039" "unprognostic (6.46e-2)" "unprognostic (3.72e-3)" "prognostic favorable (2.12e-4)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (3.53e-1)" "unprognostic (3.70e-1)" "unprognostic (8.45e-2)" "unprognostic (6.14e-2)" "unprognostic (2.94e-1)" "unprognostic (1.24e-1)" "unprognostic (8.94e-2)" "prognostic favorable (3.99e-8)" "unprognostic (7.37e-2)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" 121.3 130.0 134.6 75.3 140.6 53.8 81.4 151.4 198.8 90.2 135.4 295.2 162.2 65.9 95.2 162.8 62.6 79.3 323.1 139.4 155.1 198.9 343.5 66.5 50.9 148.1 148.8 39.4 60.8 111.4 90.5 64.6 153.5 101.5 300.1 152.7 75.1 96.3 174.2 68.8 134.8 96.2 156.1 48.9 145.9 63.7 145.6 52.8 115.5 316.7 80.0 99.5 120.1 174.0 159.9 67.0 182.9 165.2 420.3 244.3 195.2 205.1 151.0 168.4 165.8 132.8 166.7 95.8 120.5 161.8 114.0 92.9 143.0 203.0 225.6 135.5 145.9 301.0 127.6 257.4 191.8 180.4 131.4 274.0 233.7 129.0 181.4 94.7 159.8 135.1 299.7 110.3 247.3 51.1 96.1 61.1 162.7 133.7 176.5 80.9 138.0 72.1 454.1 361.1 82.7 108.2 187.6 142.0 207.0 182.9 145.0 130.0 166.1 127.4 105.2 341.1 219.1 89.7 184.1 207.2 165.2 185.7 100.6 115.7 66.2 130.5 72.9 115.4 65.8 56.6 71.5 73.6 77.2 43.6 60.3 70.5 70.0 65.6 143.2 509.4 99.4 171.5 134.6 140.6 151.4 198.8 139.4 155.1 148.1 148.8 153.5 156.1 145.6 174.0 50.1 54.5 82.4 32.3 39.7 131.2 153.1 244.8 59.2 35.7 86.4 62.0 351.5 80.1 133.0 138.0 10.4 114.1 99.5 638.8 632.0 113.3 8.4 87.3 41.2 50.8 82.0 126.8 32.8 145.0 202.7 98.1 100.9 63.6 93.3 49.7 59.6 197.9 77.1 28.6 27.3 193.5 343.8 46.9 113.3 13.0 30.7 63.4 176.1 21.5 82.7 232.5 43.3 14.1 32.9 279.4 610.7 52.3 65.5 193.5 122.4 296.4 106.0 41.2 78.9 28.8 119.8 186.1 78.7 94.2 204.6 299.9 50.7 101.5 168.0 254.2 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74834127-74893359 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 144.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 216.4;Early spermatids: 89.5;Paneth cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 172.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028587, HPA061711" Enhanced Supported Vesicles,Centrosome,Mitochondria,Cytosol NA NA 100000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Mitochondria, Cytosol" "Vesicles, Centrosome" "HPA028587: AB_10602605, HPA061711: " "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 58.2 2.7 2.7 14.6 3.9 45.7 16.0 4.8 5.6 7.8 2.7 46.6 2.8 5.1 66.1 19.9 9.7 9.5 7.9 3.5 3.6 1.9 2.7 15.2 5.8 11.1 6.3 14.9 2.9 2.5 1.9 13.1 8.5 4.9 37.3 144.0 14.7 1.1 45.6 14.6 13.0 3.3 5.9 6.9 18.7 32.8 6.0 3.7 14.1 83.7 7.8 27.1 15.9 8.6 55.9 0.4 12.5 45.4 103.3 10.8 46.5 21.3 30.6 23.4 33.4 44.0 9.8 40.7 20.1 9.9 30.2 19.0 57.0 44.7 67.0 11.6 12.5 55.1 12.4 61.0 32.5 80.8 86.3 18.2 47.3 44.5 77.1 26.3 11.3 23.0 49.2 0.2 6.9 39.6 19.8 82.0 45.3 52.4 38.2 31.8 26.2 31.7 14.2 77.2 9.2 44.6 13.5 67.4 27.4 17.8 3.6 12.8 9.4 74.0 13.4 31.2 39.2 27.1 8.2 20.2 172.5 57.9 19.9 16.8 14.0 51.7 0.2 11.0 0.6 1.2 0.8 0.1 11.8 1.3 1.2 1.2 11.2 0.0 7.7 0.3 1.5 4.7 2.7 3.9 4.8 5.6 3.5 3.6 11.1 6.3 8.5 5.9 6.0 8.6 1.6 16.0 45.3 4.9 5.7 51.6 9.5 26.7 5.7 14.8 16.0 5.6 7.2 4.3 24.2 5.5 83.4 2.3 0.6 216.4 0.0 4.6 89.5 5.8 4.1 4.4 39.0 4.2 0.2 4.5 33.5 6.4 14.8 15.0 22.2 27.2 1.4 0.3 15.8 21.9 0.1 37.7 6.1 20.8 35.1 46.0 14.6 22.8 23.2 25.3 18.9 6.3 2.1 0.5 0.7 25.6 108.3 7.9 4.7 34.3 5.4 0.2 15.2 42.1 13.1 19.9 3.3 3.9 4.2 10.7 57.0 8.2 3.6 5.8 51.7 70.0 HNF4A "HNF4, MODY, MODY1, NR2A1, TCF14" ENSG00000101076 "Hepatocyte nuclear factor 4 alpha" P41235 20 44355700-44434596 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.4;kidney: 43.3;liver: 117.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 232.6;Hepatocytes: 186.8;Intestinal goblet cells: 69.8;Paneth cells: 120.0;Proximal enterocytes: 153.9;Proximal tubular cells: 170.1;Undifferentiated cells: 136.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 48.2;liver cancer: 38.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 154.4;Hep G2: 114.8;OE19: 42.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004712, CAB019417" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB019417: AB_2295208, HPA004712: AB_1079075" "unprognostic (2.47e-1)" "unprognostic (3.08e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-2)" "unprognostic (4.79e-3)" "unprognostic (2.59e-2)" "unprognostic (3.77e-2)" "unprognostic (2.45e-2)" "unprognostic (1.05e-1)" "unprognostic (2.75e-2)" "unprognostic (8.40e-3)" "unprognostic (2.12e-1)" "unprognostic (2.70e-2)" 0.2 0.1 0.1 5.9 0.2 0.1 0.1 0.2 0.2 0.0 8.4 58.6 102.4 0.1 0.0 0.1 1.0 5.9 0.0 0.4 0.0 43.3 117.1 0.1 0.1 0.0 0.0 0.0 25.2 0.0 0.0 0.0 0.0 0.0 44.1 0.1 0.0 0.1 0.2 0.0 82.6 1.8 0.0 0.0 22.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 154.4 6.0 0.1 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 114.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 42.2 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 1.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 35.8 0.0 12.9 0.0 0.0 0.0 232.6 15.6 7.8 4.0 2.5 0.1 0.4 35.9 2.7 0.5 22.1 0.0 0.1 38.2 0.1 4.5 0.0 3.6 186.8 0.0 0.0 0.3 69.8 0.0 5.3 0.0 18.7 0.3 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 21.0 120.0 0.4 0.1 0.3 153.9 170.1 0.0 0.0 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.0 0.7 0.8 136.1 0.2 HNRNPUL2 "DKFZp762N1910, HNRPUL2" ENSG00000214753 "Heterogeneous nuclear ribonucleoprotein U like 2" Q1KMD3 11 62712630-62727457 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA041632, HPA056696, HPA067699" Supported Enhanced Nucleoplasm NA NA 88000 "Cluster 6: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA041632: AB_10960896, HPA056696: AB_2683211, HPA067699: AB_2685891" "unprognostic (3.06e-3)" "unprognostic (2.31e-1)" "unprognostic (7.48e-2)" "unprognostic (9.27e-3)" "unprognostic (4.38e-2)" "unprognostic (1.95e-1)" "unprognostic (1.91e-2)" "unprognostic (2.21e-1)" "unprognostic (2.83e-1)" "unprognostic (4.99e-3)" "unprognostic (2.35e-1)" "unprognostic (6.43e-2)" "unprognostic (2.50e-1)" "unprognostic (3.92e-2)" "unprognostic (2.17e-1)" "unprognostic (2.33e-2)" "unprognostic (6.45e-2)" 30.4 20.9 44.3 28.6 45.4 27.3 26.2 47.3 52.3 28.7 37.2 40.5 29.0 32.5 36.3 37.2 29.1 17.1 33.1 45.0 43.1 26.8 21.1 25.8 35.1 42.3 43.8 26.5 32.5 24.7 20.9 25.1 43.0 26.6 28.0 37.5 30.6 30.2 48.6 39.8 35.2 28.3 42.4 34.1 31.3 16.7 45.5 47.4 24.3 35.9 37.6 34.2 28.2 44.2 110.9 49.8 83.5 50.3 45.1 55.3 14.4 70.2 41.5 52.1 40.2 34.4 37.5 129.1 36.5 57.9 45.0 62.2 51.2 66.3 69.1 59.1 27.8 123.0 64.9 39.1 41.2 127.8 78.1 43.8 50.7 50.2 61.4 41.0 64.8 33.5 46.6 47.8 61.0 63.5 128.1 114.1 39.8 41.4 42.9 88.6 77.0 62.3 65.4 65.2 48.4 56.3 71.7 57.8 75.3 39.3 43.5 55.6 72.8 61.0 28.2 77.4 74.4 60.8 54.3 124.6 55.3 62.1 57.5 1.1 0.8 1.3 1.4 0.6 1.0 1.0 1.0 1.2 0.5 1.3 0.8 0.9 1.0 0.8 1.4 1.4 1.0 0.5 44.3 45.4 47.3 52.3 45.0 43.1 42.3 43.8 43.0 42.4 45.5 44.2 21.1 28.9 12.1 0.0 19.0 29.4 15.0 20.2 13.6 31.3 25.0 18.7 43.8 30.0 17.5 53.3 10.4 27.9 32.4 68.8 5.9 27.4 9.9 20.8 26.3 30.6 38.4 23.5 0.0 36.0 26.9 23.0 19.4 29.7 15.2 28.0 37.5 40.7 37.9 42.1 0.0 48.3 22.4 54.1 29.4 6.9 42.0 27.6 14.2 0.0 38.0 18.2 24.7 0.0 0.0 35.0 42.7 45.9 12.5 24.1 59.6 25.6 16.1 19.7 32.9 22.8 27.5 15.6 20.1 19.6 32.1 25.2 19.8 20.6 58.6 17.4 HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 41.3" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 26.9;HEK 293: 37.3;PC-3: 18.4;RT4: 42.1;THP-1: 18.2;U-937: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.0 9.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 22.3 11.9 0.0 0.0 23.3 2.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 14.1 0.0 2.2 1.6 0.0 2.5 0.2 0.0 0.1 13.2 14.4 5.1 3.3 2.8 0.2 0.0 1.6 6.2 0.7 0.0 26.9 0.0 4.3 0.0 37.3 1.9 6.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 8.7 0.0 11.8 18.4 2.7 0.6 0.0 0.1 42.1 0.7 0.0 3.3 0.0 0.3 2.0 0.0 18.2 0.0 0.5 4.5 0.3 0.1 0.0 0.0 0.0 0.0 20.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.0 0.0 0.6 0.1 4.0 1.1 8.4 0.0 0.0 0.0 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.1 2.8 0.5 0.0 0.0 0.1 0.1 0.1 0.0 10.3 3.1 HOXB13 ENSG00000159184 "Homeobox B13" Q92826 17 48724763-48728750 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 41.1;prostate: 82.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 144.7;Enteroendocrine cells: 195.2;Intestinal goblet cells: 77.0;Paneth cells: 71.3;Prostatic glandular cells: 61.9;Undifferentiated cells: 81.6" "Cancer enriched" "Detected in many" 17 "prostate cancer: 187.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "PC-3: 173.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004438, HPA062852, HPA065019" Enhanced Enhanced Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB004438: AB_627744, HPA062852: AB_2684880, HPA065019: AB_2685406" "unprognostic (4.81e-2)" "unprognostic (2.57e-2)" "unprognostic (4.40e-2)" "unprognostic (1.33e-2)" "unprognostic (5.85e-3)" "unprognostic (1.88e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (1.17e-2)" "unprognostic (6.65e-2)" "unprognostic (1.74e-1)" "unprognostic (4.27e-2)" "unprognostic (4.73e-11)" "unprognostic (1.39e-2)" "unprognostic (4.50e-2)" "unprognostic (1.12e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 24.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 82.3 41.1 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.5 4.6 0.0 1.9 6.0 0.0 13.2 0.0 0.0 0.5 0.6 0.0 0.2 0.0 2.5 3.0 0.0 3.0 0.0 1.4 0.0 8.7 0.0 0.1 1.0 4.2 2.5 1.5 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.7 0.0 0.0 0.3 0.0 2.2 173.0 0.0 1.4 0.1 0.0 0.4 0.0 0.0 2.7 0.0 4.4 0.5 0.0 0.5 0.0 0.5 4.7 4.7 1.3 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 144.7 0.0 0.0 0.6 0.0 0.0 0.2 195.2 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 77.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.3 0.0 0.0 61.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.1 0.2 0.1 81.6 14.6 HOXB7 "HOX2, HOX2C" ENSG00000260027 "Homeobox B7" P09629 17 48607232-48633572 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "epididymis: 135.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Distal enterocytes: 131.3;Distal tubular cells: 148.7;Endometrial ciliated cells: 82.9;Glandular and luminal cells: 73.1;Intestinal goblet cells: 77.6;Paneth cells: 67.8;Proximal enterocytes: 140.3;Undifferentiated cells: 63.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 5.6;spinal cord: 13.3;white matter: 7.5" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 81.9;OE19: 74.7;RPTEC TERT1: 66.5;SK-MEL-30: 84.3" "Region enriched" "Detected in single" 58 "pons and medulla: 5.7" "Region enriched" "Detected in some" 7 "spinal cord: 22.2" HPA049940 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA049940: AB_2616461" "unprognostic (6.76e-2)" "unprognostic (6.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" "unprognostic (1.39e-3)" "unprognostic (1.42e-2)" "unprognostic (1.69e-2)" "unprognostic (8.05e-3)" "unprognostic (9.16e-2)" "unprognostic (9.91e-2)" "unprognostic (7.01e-3)" "unprognostic (7.81e-3)" "unprognostic (1.17e-2)" "unprognostic (1.56e-2)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" "prognostic favorable (2.39e-4)" 13.2 11.0 0.1 3.9 0.1 0.2 12.4 0.0 0.3 21.8 0.1 16.9 1.1 5.2 135.1 0.4 8.7 0.7 0.3 0.1 0.1 30.4 0.4 2.2 2.7 5.6 0.1 0.5 0.8 5.5 0.1 5.8 1.1 2.4 15.9 0.0 0.2 16.9 1.7 3.3 18.1 6.7 13.3 3.0 5.9 1.9 0.3 0.2 0.4 0.2 0.9 7.7 5.5 7.5 48.1 20.6 0.0 0.5 14.2 21.1 0.0 0.0 0.0 0.2 0.8 31.9 0.9 0.9 81.9 19.9 23.9 6.9 0.1 0.0 0.0 22.3 15.1 7.4 15.4 0.0 11.7 0.0 14.8 13.8 6.3 14.2 0.0 3.5 43.8 14.7 8.0 0.3 46.0 12.5 1.0 0.4 0.0 74.7 0.1 0.0 39.2 5.5 66.5 15.8 0.0 0.1 16.0 0.0 84.3 1.1 3.8 4.7 38.1 0.0 24.8 20.5 36.9 2.6 6.3 0.1 0.4 0.0 58.6 0.0 0.0 0.0 1.5 0.0 0.8 0.7 0.2 0.8 0.0 1.4 0.0 0.5 0.0 1.0 0.0 0.7 2.1 0.2 0.1 0.1 0.0 0.3 0.1 0.1 5.6 0.1 1.1 13.3 0.3 7.5 55.4 0.0 0.0 0.0 2.0 5.5 0.9 0.0 0.6 0.0 0.9 1.0 0.3 0.0 0.0 86.5 0.0 6.8 1.6 131.3 148.7 0.1 0.3 82.9 6.3 20.3 36.5 1.3 0.0 1.3 19.3 6.4 0.0 73.1 5.1 0.0 1.4 0.2 11.5 0.0 0.0 77.6 0.0 10.6 5.4 0.2 0.6 2.8 24.9 0.0 1.7 0.0 2.1 0.0 0.0 0.3 67.8 0.0 5.1 0.6 140.3 31.6 0.0 0.0 0.0 3.5 8.9 1.7 20.9 0.2 2.0 1.8 2.6 0.1 63.1 3.5 HOXD1 "HOX4, HOX4G" ENSG00000128645 "Homeobox D1" Q9GZZ0 2 176188668-176190907 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.9;epididymis: 7.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 18.5;Distal enterocytes: 20.3;Distal tubular cells: 25.4;Endothelial cells: 18.8;Intestinal goblet cells: 20.6;Oligodendrocytes: 28.0;Proximal enterocytes: 22.0;Undifferentiated cells: 28.6" "Cancer enriched" "Detected in many" 5 "ovarian cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.6;Hep G2: 7.2;RPTEC TERT1: 21.3;RT4: 16.9;SCLC-21H: 5.7" "Region enriched" "Detected in single" 5 "pons and medulla: 1.1" "Low region specificity" "Detected in many" "HPA040062, HPA056900" Enhanced Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA040062: AB_2676826, HPA056900: AB_2683270" "unprognostic (8.78e-2)" "unprognostic (9.97e-2)" "unprognostic (7.11e-3)" "unprognostic (1.06e-3)" "unprognostic (2.70e-1)" "unprognostic (3.19e-2)" "unprognostic (7.33e-2)" "unprognostic (4.10e-2)" "unprognostic (2.85e-1)" "unprognostic (2.44e-1)" "unprognostic (9.64e-2)" "unprognostic (4.02e-1)" "unprognostic (1.54e-5)" "unprognostic (4.33e-3)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" 2.0 0.2 1.7 0.5 5.2 0.0 1.6 6.1 5.0 0.3 0.8 2.9 0.3 0.4 7.5 0.5 4.8 0.7 0.1 1.6 3.3 6.5 0.0 3.2 0.4 19.9 5.8 0.4 0.2 0.0 0.0 0.0 8.2 1.0 2.0 0.0 0.2 2.6 0.1 0.6 3.3 0.3 6.5 1.1 0.4 1.7 5.3 0.1 0.1 0.3 0.1 2.2 0.4 10.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 6.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 7.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 21.3 16.9 5.7 1.0 0.0 0.0 1.2 0.8 0.0 0.0 3.9 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 5.2 6.1 5.0 1.6 3.3 19.9 5.8 8.2 6.5 5.3 10.1 14.2 3.2 18.5 0.0 0.1 4.2 0.2 0.0 0.0 0.0 0.9 1.3 0.1 0.0 2.5 7.3 0.0 0.0 0.1 20.3 25.4 0.0 0.1 0.2 0.2 18.8 6.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 5.6 0.4 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 28.0 0.1 13.2 0.4 0.9 0.7 22.0 3.2 0.0 0.0 0.0 0.6 1.1 3.4 9.5 0.3 2.6 0.0 0.5 0.5 28.6 2.7 HOXD11 "HOX4, HOX4F" ENSG00000128713 "Homeobox D11" P31277 2 176104216-176109754 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.1;intestine: 3.8;kidney: 4.7;prostate: 3.3;vagina: 4.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 26.7;Collecting duct cells: 22.0;Distal enterocytes: 22.8;Endometrial stromal cells: 29.0;Enteroendocrine cells: 20.6;Urothelial cells: 14.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 21.9;RPTEC TERT1: 2.6;SCLC-21H: 6.1;U-251 MG: 4.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 40 "spinal cord: 3.9" HPA055155 Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA055155: AB_2682719" "unprognostic (1.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.05e-2)" "unprognostic (1.85e-3)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (2.13e-2)" "unprognostic (6.73e-2)" "unprognostic (5.00e-2)" "unprognostic (2.11e-8)" "unprognostic (2.09e-3)" "unprognostic (2.49e-2)" "unprognostic (2.27e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 3.8 0.0 7.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.0 0.0 0.9 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 1.4 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 6.1 0.3 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.4 26.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.0 0.0 0.1 0.0 22.8 9.8 0.0 0.0 1.1 29.0 1.7 20.6 0.0 0.0 0.0 0.1 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 8.6 0.0 0.0 1.2 0.2 0.9 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.8 1.2 0.0 8.8 0.0 0.3 0.0 0.0 0.0 0.1 2.3 0.1 0.4 0.0 0.9 0.0 0.1 0.0 9.2 14.0 HOXD13 "HOX4I, SPD" ENSG00000128714 "Homeobox D13" P35453 2 176092721-176095944 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "cervix: 14.2;intestine: 18.2;prostate: 9.7;seminal vesicle: 16.3;vagina: 17.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 12.4;Distal enterocytes: 5.5;Enteroendocrine cells: 29.0;Intestinal goblet cells: 9.1;Paneth cells: 5.5;Prostatic glandular cells: 6.3;Undifferentiated cells: 9.9;Urothelial cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.4;HEK 293: 53.3;HL-60: 61.7;JURKAT: 16.7;NB-4: 36.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064064 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA064064: AB_2685186" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (2.52e-3)" "unprognostic (7.25e-2)" "unprognostic (2.08e-2)" "unprognostic (4.62e-2)" "unprognostic (1.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.82e-4)" "unprognostic (4.95e-2)" "unprognostic (3.70e-2)" "unprognostic (9.98e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.2 0.0 18.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 9.7 7.6 0.0 0.0 16.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 2.2 4.7 0.0 0.0 0.0 0.0 0.0 5.1 0.0 18.4 0.0 2.8 0.0 53.3 8.3 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 3.9 0.0 0.0 0.0 0.0 36.3 1.9 0.0 3.0 0.0 0.2 0.0 0.0 0.4 15.2 3.7 3.8 0.0 8.9 0.2 0.0 0.0 0.0 1.8 0.0 0.8 5.1 0.0 0.0 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.9 0.0 0.1 0.1 29.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.4 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 9.9 6.7 HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 235.0;urinary bladder: 376.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 457.8;Extravillous trophoblasts: 701.7;granulocytes: 864.5;Proximal enterocytes: 500.6;Urothelial cells: 922.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 123.7;T-reg: 45.0" "Group enriched" "Detected in many" 73 "granulocytes: 123.7;T-cells: 45.0" "Cell line enhanced" "Detected in many" "A549: 157.8;ASC diff: 110.6;HEL: 355.0;OE19: 102.1;RT4: 565.7;SuSa: 121.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" 9.2 16.5 1.0 11.4 0.7 2.7 159.9 0.5 1.2 32.2 8.7 60.9 152.2 45.5 36.5 81.6 13.4 24.9 1.6 1.2 2.8 60.2 210.8 91.0 5.5 1.4 2.0 1.1 2.6 85.3 2.1 99.1 1.0 10.2 57.4 1.0 7.7 4.0 2.5 39.8 117.3 63.7 0.8 10.3 235.0 1.6 2.2 12.2 1.7 3.0 26.6 376.0 83.0 0.7 0.0 157.8 0.0 0.0 110.6 5.4 0.4 0.0 0.0 0.0 0.4 45.1 0.2 0.1 0.0 0.0 0.2 14.2 16.0 0.0 0.0 0.3 2.9 355.0 10.8 0.3 0.0 2.1 0.9 5.6 2.6 0.0 0.1 0.1 0.0 22.6 0.2 0.0 0.0 0.3 1.2 0.3 1.4 102.1 7.4 16.3 0.3 1.3 36.2 565.7 0.9 0.4 0.0 1.3 3.5 121.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 28.4 0.0 0.1 0.3 0.2 0.0 123.7 0.3 16.6 9.9 0.0 15.6 0.4 5.2 4.5 0.7 0.2 1.6 4.0 1.3 1.1 0.0 0.0 45.0 3.0 1.0 0.7 0.5 1.2 1.2 2.8 1.4 2.0 1.0 0.8 2.2 0.7 3.4 16.0 33.0 0.0 4.3 17.3 80.8 6.9 45.5 3.3 14.5 6.7 0.8 35.8 23.6 22.0 0.0 48.5 38.5 457.8 21.5 7.4 1.4 5.7 5.4 18.2 8.4 17.2 0.8 94.5 701.7 25.3 196.7 36.4 864.5 1.5 13.9 245.7 21.4 0.0 9.7 60.7 0.0 14.8 19.5 0.5 19.9 29.2 76.5 5.6 2.9 0.0 10.3 0.0 4.1 42.4 254.7 0.0 50.2 76.8 500.6 131.1 4.4 0.8 0.0 2.4 3.7 0.5 1.0 53.4 22.4 56.6 42.7 65.0 58.9 922.8 HPS1 "BLOC3S1, HPS" ENSG00000107521 "HPS1 biogenesis of lysosomal organelles complex 3 subunit 1" Q92902 10 98416198-98446935 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061260 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA061260: AB_2684459" "unprognostic (1.31e-1)" "prognostic favorable (3.37e-5)" "unprognostic (8.95e-2)" "prognostic favorable (2.93e-5)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.19e-1)" "unprognostic (9.38e-3)" "prognostic favorable (1.26e-4)" "unprognostic (2.39e-1)" "unprognostic (2.44e-3)" "unprognostic (5.64e-3)" "unprognostic (2.24e-1)" "unprognostic (1.76e-1)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "unprognostic (3.06e-2)" "unprognostic (8.30e-3)" 16.8 22.2 12.9 13.4 12.7 37.2 15.3 12.0 15.2 15.6 14.5 18.7 18.4 14.1 6.2 14.1 13.9 13.9 13.2 13.4 12.7 16.3 19.9 16.4 21.3 13.5 12.9 12.3 21.8 6.2 13.4 8.9 13.3 16.1 9.1 2.1 20.4 10.4 7.3 16.2 24.4 7.9 12.6 25.2 18.4 12.8 14.2 10.7 12.7 3.3 12.1 16.3 14.1 12.4 16.9 15.3 1.2 20.6 16.6 19.6 9.4 13.4 43.4 14.3 22.0 10.5 14.7 17.4 16.6 16.3 19.8 20.1 7.7 7.6 6.5 31.4 17.4 27.1 10.0 20.5 37.7 22.0 50.6 21.9 21.1 15.3 19.5 16.7 18.1 11.3 12.0 29.5 15.1 24.0 8.0 18.4 4.2 11.8 9.4 12.8 0.0 12.7 16.6 19.0 3.2 12.3 9.7 7.2 27.6 7.9 16.9 23.5 28.9 10.8 13.8 23.8 14.5 17.3 12.3 12.9 33.0 35.4 12.6 20.2 19.3 36.5 11.3 27.5 11.4 12.4 8.9 10.3 22.6 12.4 6.1 7.4 13.5 16.9 27.4 16.0 14.6 13.6 12.9 12.7 12.0 15.2 13.4 12.7 13.5 12.9 13.3 12.6 14.2 12.4 16.8 19.2 23.8 17.6 49.9 22.3 48.2 40.8 46.1 3.7 40.5 43.9 24.2 28.6 30.2 23.9 2.1 28.3 33.7 72.0 19.6 50.7 33.5 12.4 18.3 18.5 27.1 83.9 11.4 50.3 29.7 27.9 43.8 14.1 29.8 11.6 28.9 26.6 80.6 0.0 14.1 37.5 22.4 62.6 48.7 56.8 27.7 57.4 35.6 12.2 78.6 17.8 60.8 5.5 18.1 60.5 83.0 26.7 43.7 47.7 80.7 59.3 14.7 3.1 13.1 22.3 22.4 28.6 9.5 33.3 18.0 24.6 39.7 41.3 33.1 69.2 HRCT1 "LGLL338, PRO537, UNQ338" ENSG00000196196 "Histidine rich carboxyl terminus 1" Q6UXD1 9 35906202-35907136 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.4;breast: 24.9" "Cell type enhanced" "Detected in many" "Adipocytes: 72.4;Distal enterocytes: 232.3;Intestinal goblet cells: 57.8;Paneth cells: 316.5;Proximal enterocytes: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 18.0;HBEC3-KT: 10.3;HeLa: 15.9;Hep G2: 11.7;U-2197: 27.0;U-251 MG: 13.1" "Low region specificity" "Detected in some" HPA067038 Approved Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA067038: AB_2685767" "unprognostic (2.48e-2)" "unprognostic (4.88e-2)" "unprognostic (2.43e-2)" "unprognostic (2.49e-1)" "unprognostic (5.69e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.63e-2)" "unprognostic (2.53e-2)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-1)" "unprognostic (2.00e-1)" "unprognostic (9.41e-2)" "unprognostic (2.80e-1)" "unprognostic (9.43e-2)" 29.4 1.8 3.9 1.8 4.0 0.0 24.9 3.3 4.9 4.1 2.7 20.6 8.9 6.0 1.0 1.8 5.5 0.3 9.7 3.7 3.3 7.4 1.6 4.8 0.6 3.9 3.6 2.7 1.3 0.5 1.1 2.9 3.9 4.6 11.8 1.1 6.7 2.7 5.4 6.4 11.0 1.8 3.6 0.8 3.6 2.4 3.8 0.1 4.9 3.8 0.2 7.4 4.4 3.2 0.4 0.2 0.0 0.2 0.8 5.9 0.0 0.2 0.5 0.1 0.0 0.2 1.7 0.0 18.0 0.4 3.4 0.0 0.0 10.3 0.0 0.0 0.0 0.0 15.9 11.7 2.3 0.0 0.0 5.8 5.2 2.0 1.2 0.8 6.3 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 4.8 2.4 0.0 0.3 0.1 3.4 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.2 5.3 0.2 5.3 27.0 13.1 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 3.3 4.9 3.7 3.3 3.9 3.6 3.9 3.6 3.8 3.2 72.4 6.4 1.5 0.3 0.3 2.2 0.4 0.4 0.6 2.0 2.4 11.0 1.2 4.3 2.1 0.0 0.0 23.3 0.5 232.3 1.9 1.9 0.1 2.1 0.4 40.8 1.2 0.0 0.4 0.2 6.2 7.4 0.0 0.8 0.0 1.0 50.7 0.6 1.8 0.0 0.2 57.8 0.0 0.9 2.0 0.5 10.8 0.4 1.8 0.0 0.0 10.8 0.0 0.0 0.1 4.6 316.5 9.4 0.0 0.8 64.6 13.0 0.9 2.5 13.1 3.5 4.7 0.1 0.2 0.1 1.8 2.6 0.6 0.3 24.0 0.4 HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 249.9;kidney: 335.2;salivary gland: 260.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 191.3;Distal enterocytes: 476.1;Intestinal goblet cells: 288.8;Paneth cells: 226.2;Proximal enterocytes: 270.2;Syncytiotrophoblasts: 114.5;Undifferentiated cells: 170.9" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 11.4;OE19: 29.0;RPMI-8226: 13.9;RT4: 13.9;SCLC-21H: 14.9;SK-BR-3: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB032443, HPA042186, HPA056385" Enhanced Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" 2.1 5.4 1.6 13.4 4.6 0.1 14.0 2.8 2.8 15.5 0.7 249.9 40.0 11.8 4.0 10.9 10.4 6.8 1.9 1.6 1.3 335.2 5.5 3.2 1.0 2.7 1.3 9.3 7.4 3.6 0.5 13.0 3.3 12.9 102.2 0.0 260.2 6.2 0.9 66.1 141.8 18.3 1.5 7.0 9.8 2.5 2.0 0.4 11.1 0.2 0.9 5.3 23.6 2.4 3.6 1.1 0.4 1.4 0.1 1.7 3.6 0.0 0.0 0.1 0.1 6.1 1.3 0.0 2.7 0.1 0.1 7.8 5.1 0.5 0.0 0.0 1.8 0.0 0.7 6.6 0.6 0.7 0.0 1.7 3.0 0.3 0.1 0.0 0.0 4.6 0.4 0.0 0.0 3.8 0.2 0.2 11.4 29.0 1.0 0.0 0.2 13.9 0.5 13.9 14.9 1.0 0.8 13.4 0.6 1.3 6.5 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.6 2.8 2.8 1.6 1.3 2.7 1.3 3.3 1.5 2.0 2.4 0.7 0.0 0.5 0.0 1.1 1.5 7.2 1.3 1.2 0.0 4.8 2.2 0.5 30.0 2.3 191.3 0.0 1.2 0.3 476.1 45.0 2.1 0.2 17.4 25.2 0.5 26.9 0.0 1.1 3.0 0.7 7.1 7.1 43.5 8.9 43.4 1.1 1.2 1.4 0.0 0.8 288.8 4.1 0.3 0.5 0.5 25.4 0.7 1.8 0.0 0.0 0.0 0.0 0.5 0.3 0.6 226.2 6.8 0.2 13.5 270.2 16.3 0.4 0.0 13.1 0.3 3.9 0.2 1.6 3.5 3.4 114.5 1.2 16.7 170.9 10.5 HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 269.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 283.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" 30.0 57.5 29.6 32.3 35.9 18.6 29.6 33.2 46.1 24.2 34.7 88.4 135.9 13.8 31.4 50.0 13.5 44.8 21.2 29.2 31.3 32.6 97.8 39.1 28.5 34.1 31.7 16.2 26.7 27.8 39.9 28.5 34.6 22.4 80.7 1.9 35.0 20.6 46.2 36.0 121.4 14.4 32.3 38.6 75.4 21.4 32.3 20.2 51.3 21.3 27.4 37.7 35.4 45.8 109.6 177.5 3.9 0.2 52.5 39.4 38.7 46.4 45.8 35.3 41.8 103.2 93.8 24.8 93.1 58.3 136.6 149.7 0.0 28.2 33.9 283.9 21.4 30.8 170.1 0.2 125.3 11.3 139.6 57.3 196.0 28.7 44.5 0.0 102.2 0.0 76.8 31.6 66.3 102.0 0.4 7.0 56.5 193.2 87.1 23.2 0.3 89.8 48.1 60.1 47.2 0.5 150.9 59.1 73.6 18.0 123.7 57.0 125.4 25.1 54.8 51.0 1.2 33.5 44.7 0.6 0.4 76.9 111.4 233.4 133.3 171.1 64.3 126.4 73.4 65.9 74.1 69.2 76.9 76.4 63.9 62.7 304.1 64.5 135.2 23.2 140.9 116.7 29.6 35.9 33.2 46.1 29.2 31.3 34.1 31.7 34.6 32.3 32.3 45.8 49.2 25.6 9.6 3.9 28.0 36.3 60.0 74.2 67.2 1.0 32.9 26.7 11.6 102.9 43.7 47.8 0.0 53.7 16.7 175.6 31.3 91.4 51.1 19.3 6.1 29.5 24.1 28.8 12.9 72.3 118.0 23.8 49.5 34.5 22.9 22.7 33.2 77.5 82.8 3.3 9.1 100.3 105.8 54.0 27.6 59.5 19.9 61.3 44.4 8.4 114.6 9.5 39.1 3.5 40.2 94.7 157.3 9.4 21.4 65.2 269.7 69.0 37.4 1.7 13.1 19.2 28.5 45.5 21.5 87.2 42.1 61.6 33.4 13.2 87.8 62.7 IGSF3 "EWI-3, MGC117164, V8" ENSG00000143061 "Immunoglobulin superfamily member 3" O75054 1 116574399-116667755 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 256.5;WM-115: 239.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036305, HPA036306" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA036305: AB_2675050, HPA036306: AB_10671245" "unprognostic (9.87e-2)" "unprognostic (3.64e-1)" "unprognostic (9.51e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.97e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (4.03e-6)" "unprognostic (9.40e-2)" "unprognostic (4.41e-1)" "unprognostic (2.42e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.18e-1)" "prognostic favorable (2.87e-6)" "unprognostic (5.29e-2)" "unprognostic (4.23e-2)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" 1.5 1.8 0.9 1.3 1.8 0.3 8.5 1.8 3.9 6.1 1.4 6.5 7.7 2.9 5.7 23.2 2.0 3.2 9.1 1.1 3.0 11.4 0.5 8.4 0.5 2.0 3.5 0.4 2.6 2.1 2.4 11.1 2.3 5.6 5.8 7.5 9.1 5.7 1.6 18.2 8.8 2.9 4.7 0.4 8.7 4.1 4.9 10.9 8.3 1.5 5.3 5.0 10.9 2.9 22.3 36.9 28.2 7.2 6.4 13.4 75.5 0.1 1.0 2.9 1.0 21.5 12.4 0.0 11.4 0.3 15.8 60.7 12.6 30.4 1.3 256.5 9.3 12.1 13.7 0.6 0.0 1.2 22.2 1.7 23.1 0.2 5.2 5.3 0.2 4.1 3.7 0.2 0.6 78.0 0.9 0.8 17.8 13.4 0.9 9.1 34.6 0.1 21.6 27.5 16.4 50.0 8.9 84.7 55.1 53.9 28.7 1.5 0.1 4.9 16.4 0.2 23.0 0.3 1.3 0.1 2.2 0.7 239.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.8 1.8 3.9 1.1 3.0 2.0 3.5 2.3 4.7 4.9 2.9 3.5 16.0 36.0 1.0 0.0 19.6 8.6 23.2 23.9 29.3 17.1 10.8 16.1 7.2 9.1 14.7 0.0 13.7 0.1 29.3 3.9 14.0 2.1 8.3 2.1 3.3 3.0 0.0 11.8 1.9 27.3 7.8 16.8 14.4 1.3 7.3 1.8 0.6 2.1 6.7 18.8 5.0 2.0 1.3 11.1 2.2 1.2 0.5 8.8 0.0 3.1 11.3 0.0 1.5 0.4 16.4 7.3 0.0 0.0 10.2 15.4 11.4 11.3 0.8 0.0 26.4 2.8 0.5 3.8 30.6 27.7 13.3 0.4 3.5 9.3 11.4 IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.8;skin 1: 31.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.6;Gastric mucus-secreting cells: 58.1;Intestinal goblet cells: 52.1;Paneth cells: 37.7;Proximal enterocytes: 74.4;Undifferentiated cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 38.5;hTCEpi: 16.5;T-47d: 19.4" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019011: AB_1851667" "unprognostic (1.08e-2)" "unprognostic (7.58e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.81e-2)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (6.69e-2)" "unprognostic (6.31e-2)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-2)" 6.1 0.4 0.5 1.4 1.6 0.0 5.9 2.2 1.0 4.5 0.3 16.6 20.8 1.8 2.7 7.5 2.5 6.8 1.2 0.4 0.9 2.8 0.8 8.1 0.4 1.5 0.4 0.6 9.7 4.2 1.6 1.1 2.3 4.8 13.8 0.1 6.3 3.3 0.4 31.0 20.4 1.4 0.4 1.0 16.7 0.2 0.3 2.8 3.2 0.2 1.7 1.7 6.6 0.4 2.6 0.3 0.0 0.1 15.5 38.5 11.3 1.0 1.4 0.3 0.9 2.9 2.3 0.0 0.6 2.7 0.0 7.1 0.0 6.2 0.1 0.1 0.1 0.8 0.2 6.8 0.4 0.0 3.2 2.4 16.5 0.0 0.1 0.0 0.1 2.5 0.1 0.0 0.7 3.1 0.4 11.3 0.1 8.1 0.8 0.0 0.0 0.1 2.8 3.2 0.6 0.2 0.0 6.5 0.0 0.3 19.4 0.3 1.5 0.1 0.0 0.3 0.2 0.2 0.1 0.0 0.4 6.5 0.2 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 2.2 1.0 0.4 0.9 1.5 0.4 2.3 0.4 0.3 0.4 3.4 6.4 1.1 3.3 1.0 14.5 11.9 2.3 14.2 3.0 8.4 8.3 0.9 15.7 2.0 16.5 0.0 4.3 0.8 92.6 7.9 2.7 0.2 1.4 2.0 1.3 33.6 9.0 2.4 4.8 1.8 4.9 58.1 1.3 0.0 1.2 1.8 15.4 2.6 1.7 1.9 52.1 2.0 2.2 3.5 0.4 2.1 1.6 5.4 0.0 1.0 4.7 2.1 2.0 0.6 2.5 37.7 3.4 0.8 6.1 74.4 8.0 1.0 1.0 19.7 1.8 7.2 1.6 2.3 11.8 14.8 0.8 2.8 1.0 40.8 4.6 IL22RA1 "CRF2-9, IL22R" ENSG00000142677 "Interleukin 22 receptor subunit alpha 1" Q8N6P7 1 24119771-24143140 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 199.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 34.8;Exocrine glandular cells: 12.0;Pancreatic endocrine cells: 11.3;Paneth cells: 33.4;Proximal enterocytes: 44.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 11.3;Hep G2: 8.1;OE19: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.68e-3)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-3)" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-3)" "unprognostic (1.12e-1)" "unprognostic (7.63e-2)" "unprognostic (1.72e-3)" "unprognostic (2.28e-1)" "unprognostic (4.78e-3)" "unprognostic (1.05e-2)" "unprognostic (2.57e-1)" "unprognostic (2.63e-1)" "unprognostic (1.64e-2)" 0.7 0.4 0.0 1.2 0.0 0.0 2.0 0.3 0.3 4.0 0.0 11.4 20.0 0.2 0.1 17.8 1.5 2.6 0.3 0.5 0.1 2.1 7.0 0.8 0.0 0.1 0.0 0.3 199.3 0.0 2.1 0.1 0.1 0.7 10.0 0.2 2.9 0.4 0.4 40.1 28.3 0.4 0.1 0.0 3.5 0.4 0.0 0.0 2.3 0.0 2.4 0.3 7.0 0.1 2.9 2.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 1.3 1.5 11.3 4.8 0.0 0.9 0.3 4.7 5.0 0.6 3.0 0.4 3.7 0.0 0.0 1.4 8.1 0.0 0.0 0.0 0.0 1.8 0.4 0.1 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.1 0.1 18.7 1.0 0.0 0.0 0.1 0.0 0.6 0.1 0.1 1.4 0.0 1.6 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 4.2 0.8 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.9 0.4 0.7 2.8 0.0 0.1 0.3 0.3 1.5 0.2 0.0 0.0 0.0 0.0 34.8 0.0 1.1 0.3 0.5 0.1 0.0 0.0 0.0 0.2 12.0 0.0 0.3 3.6 0.5 0.0 0.5 0.0 5.8 0.0 0.0 0.1 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.4 0.0 0.0 0.1 11.3 33.4 0.0 0.0 0.2 44.0 1.4 0.4 0.0 0.0 0.0 0.1 0.0 0.0 2.3 1.1 0.0 0.0 0.0 7.0 0.2 ILDR1 "DFNB42, MGC50831" ENSG00000145103 "Immunoglobulin like domain containing receptor 1" Q86SU0 3 121987323-122022247 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Club cells: 14.7;Collecting duct cells: 20.2;Cytotrophoblasts: 16.6;Distal enterocytes: 17.5;Glandular and luminal cells: 13.5;Respiratory ciliated cells: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 4 "B-cells: 1.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 6.3;HDLM-2: 8.2;MCF7: 5.1;RT4: 7.5;T-47d: 5.3;U-266/70: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA018207 Approved "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018207: AB_1851742" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (9.24e-2)" "unprognostic (4.46e-3)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (2.04e-1)" "unprognostic (7.78e-2)" "unprognostic (2.37e-1)" "prognostic favorable (5.79e-9)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (3.25e-3)" "unprognostic (2.21e-2)" 0.0 0.7 0.2 1.3 0.1 0.3 2.9 0.2 0.3 11.7 0.1 8.2 3.3 1.0 12.8 3.8 5.1 3.3 0.0 0.1 0.0 6.5 0.2 2.9 1.1 0.1 0.1 0.0 6.7 15.7 2.4 1.8 0.1 6.9 7.2 0.2 8.0 10.6 0.1 1.2 2.4 0.3 0.0 0.6 0.8 0.6 0.1 0.8 7.3 0.0 2.2 2.2 1.1 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 6.3 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 8.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 5.1 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.4 2.8 7.5 0.2 0.0 0.0 0.7 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 6.1 1.4 1.1 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.2 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 12.8 7.4 0.3 1.3 0.0 0.8 7.5 0.0 0.0 4.2 2.4 0.7 4.3 14.7 20.2 0.0 16.6 0.1 17.5 1.9 7.5 0.2 6.3 1.6 0.1 3.5 0.0 0.5 3.7 0.5 0.1 1.1 13.5 0.0 0.2 0.0 0.1 1.2 0.0 0.5 7.9 8.2 0.6 0.0 0.0 0.0 0.3 1.8 1.9 0.0 0.0 0.0 0.0 0.2 2.6 8.9 0.0 2.1 2.2 2.5 2.1 13.7 0.0 0.0 0.0 0.6 0.0 0.1 5.9 0.6 5.1 0.1 0.0 7.8 3.5 IMPA1 IMPA ENSG00000133731 "Inositol monophosphatase 1" P29218 8 81656914-81686331 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037489 Approved NA No 310000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA037489: AB_10671757" "unprognostic (1.78e-1)" "unprognostic (3.59e-2)" "unprognostic (6.95e-3)" "unprognostic (2.15e-3)" "unprognostic (1.31e-1)" "unprognostic (6.27e-2)" "unprognostic (3.80e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-1)" "unprognostic (4.68e-2)" "unprognostic (7.78e-2)" "unprognostic (6.26e-2)" "unprognostic (2.52e-2)" "unprognostic (5.87e-2)" "unprognostic (1.84e-1)" "unprognostic (2.42e-1)" "unprognostic (5.41e-3)" 12.8 11.3 12.7 12.7 13.3 27.0 10.2 11.8 15.8 8.9 14.8 26.9 23.5 10.4 11.7 20.7 11.8 11.8 25.8 14.6 12.6 16.4 31.3 10.2 17.6 10.9 13.4 13.5 8.6 15.5 10.1 8.2 13.0 11.0 28.4 18.2 8.3 8.1 14.1 5.1 23.2 18.0 12.4 11.2 14.7 38.2 12.1 19.6 21.8 29.0 16.3 14.0 10.5 15.1 12.5 34.6 23.3 17.2 14.0 21.9 9.8 35.7 26.5 31.3 36.7 16.3 20.1 47.2 27.5 26.2 45.6 9.4 27.1 12.0 41.3 50.7 26.5 35.7 19.2 20.8 23.8 36.7 35.0 20.3 17.6 24.9 48.2 30.2 35.2 35.6 32.8 38.7 30.6 8.7 46.1 18.4 10.1 32.2 37.2 21.2 16.9 19.2 31.7 43.5 9.3 38.7 23.9 6.2 41.3 39.6 20.4 27.4 26.4 24.9 32.8 19.8 44.1 45.2 58.5 67.4 29.4 20.7 35.9 50.5 6.6 29.4 13.6 10.3 16.8 20.3 13.5 14.9 7.5 13.7 14.0 16.8 11.2 20.5 11.8 12.0 19.6 9.5 12.7 13.3 11.8 15.8 14.6 12.6 10.9 13.4 13.0 12.4 12.1 15.1 22.2 16.0 12.7 15.3 25.7 13.8 16.9 16.8 28.5 15.8 8.5 6.9 38.3 21.5 17.3 9.2 14.6 9.7 29.4 54.4 31.3 16.2 4.0 23.2 19.7 16.5 21.5 11.6 19.4 20.3 11.0 16.1 12.2 17.3 33.0 11.5 13.9 32.9 14.3 25.2 12.5 19.8 18.3 16.2 13.1 8.2 15.5 16.4 12.4 12.2 21.9 23.4 13.4 14.1 14.0 19.0 62.3 15.1 18.1 14.4 30.4 30.7 25.1 15.9 13.1 15.5 17.0 78.4 19.2 26.9 8.7 3.0 26.2 18.7 22.3 21.3 INF2 "C14orf151, C14orf173, MGC13251" ENSG00000203485 "Inverted formin 2" Q27J81 14 104681146-104722535 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.3;Gastric mucus-secreting cells: 183.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 100.8" "Region enhanced" "Detected in all" "basal ganglia: 224.1" "Low region specificity" "Detected in all" HPA000724 Approved Approved "Nuclear bodies,Endoplasmic reticulum" NA NA 3000000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Nuclear bodies" "HPA000724: AB_1078325" "unprognostic (1.42e-1)" "unprognostic (9.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.00e-2)" "unprognostic (1.49e-2)" "unprognostic (5.90e-3)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.13e-2)" "unprognostic (9.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-2)" "unprognostic (1.36e-3)" "unprognostic (7.24e-2)" "unprognostic (4.01e-1)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.70e-2)" 42.8 21.4 14.0 8.4 29.6 7.5 35.2 18.3 29.5 28.7 1.4 40.4 21.2 24.3 2.3 20.4 20.9 8.9 24.1 14.7 14.7 27.3 30.2 34.3 6.9 30.7 25.5 13.6 15.7 2.0 8.3 11.7 27.5 23.2 4.7 3.3 17.9 7.5 13.7 26.9 31.7 4.4 12.2 31.4 34.7 32.2 26.3 2.1 20.8 1.5 3.4 30.2 28.5 71.2 26.3 92.1 9.9 16.0 7.6 12.2 84.2 49.0 14.5 21.9 14.0 35.5 40.2 3.7 46.6 17.9 17.0 43.3 9.4 22.7 9.5 18.5 26.6 22.0 59.9 23.9 16.5 6.8 21.0 11.4 14.5 15.8 6.8 15.0 24.1 9.1 10.7 10.5 18.0 30.0 10.2 17.9 17.1 18.3 100.8 29.8 19.2 9.4 12.6 38.0 20.5 12.8 26.4 36.7 11.7 8.0 8.0 4.9 49.9 29.4 22.1 45.7 22.5 6.9 3.7 3.7 41.2 12.1 25.1 0.5 2.1 0.1 0.9 0.7 0.7 1.6 3.2 0.6 2.4 1.5 2.5 1.6 1.6 1.2 0.1 5.1 4.0 3.2 14.0 29.6 18.3 29.5 14.7 14.7 30.7 25.5 27.5 12.2 26.3 71.2 48.8 64.1 13.4 10.1 22.5 22.7 17.5 19.0 17.1 0.3 16.5 14.6 14.3 28.6 15.0 3.7 0.0 54.8 5.2 229.3 5.9 24.1 1.2 7.8 8.6 29.8 17.4 17.2 16.7 25.5 87.8 17.9 183.0 18.2 14.7 8.4 25.4 29.8 32.6 0.0 1.9 86.2 12.2 21.8 35.6 2.1 5.6 25.5 8.8 20.6 14.0 55.3 1.0 11.1 89.6 58.1 110.7 4.5 7.8 26.6 90.4 7.3 9.4 2.0 32.9 5.7 36.1 1.1 4.5 8.5 18.8 31.6 9.3 12.9 66.9 38.2 INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239147 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 344.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Golgi apparatus" "HPA037601: AB_10672281" "unprognostic (2.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.68e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" 45.2 56.4 39.0 34.4 43.4 51.3 44.7 41.3 40.5 63.8 47.3 87.5 35.9 56.1 18.2 34.6 61.3 33.7 73.6 33.2 42.5 60.0 36.6 61.8 36.8 53.9 43.2 68.6 55.7 36.4 60.5 39.7 45.8 68.7 23.3 14.9 53.8 39.5 116.6 31.4 57.1 33.4 45.0 66.1 60.8 24.2 48.8 19.3 67.7 43.0 23.2 59.9 43.4 41.2 28.7 62.1 71.5 49.8 35.4 41.1 122.5 118.9 61.2 80.6 49.6 84.3 72.2 79.5 125.6 101.7 57.8 106.7 60.4 37.6 28.0 101.9 59.1 84.8 344.5 31.9 68.1 56.1 176.7 58.2 39.1 78.0 31.4 100.5 44.2 29.3 59.7 34.7 45.1 78.8 42.1 224.9 67.7 20.7 93.7 185.0 161.0 18.2 94.8 48.6 33.8 48.6 133.9 85.1 182.8 36.6 88.8 106.0 74.5 86.4 96.7 129.9 43.1 94.5 17.5 80.1 24.7 51.7 47.2 2.5 3.5 3.3 1.9 2.0 1.7 0.9 1.6 1.3 2.4 1.0 1.1 1.6 2.3 2.2 3.6 1.8 1.5 1.8 39.0 43.4 41.3 40.5 33.2 42.5 53.9 43.2 45.8 45.0 48.8 41.2 13.9 3.2 12.8 47.0 8.1 7.1 4.9 10.8 14.2 1.7 20.3 17.3 13.6 11.5 11.7 12.9 27.1 27.9 9.1 28.3 1.9 11.6 1.5 14.6 16.3 11.2 22.7 5.7 2.6 12.5 15.4 10.8 24.5 25.5 7.6 21.0 8.9 12.5 21.7 10.1 2.2 16.4 18.3 27.6 16.2 2.1 9.9 29.8 10.6 18.7 17.6 16.8 14.4 15.1 6.1 14.9 17.5 13.9 7.8 7.8 15.2 16.2 10.2 17.2 6.6 12.9 14.5 1.4 4.9 6.7 4.8 32.4 11.6 10.1 21.8 5.4 INTS1 "DKFZp586J0619, INT1, KIAA1440, NET28" ENSG00000164880 "Integrator complex subunit 1" Q8N201 7 1470277-1504389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021658, HPA053009" Approved Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA021658: AB_1852402, HPA053009: AB_2682016" "unprognostic (3.20e-2)" "unprognostic (2.85e-2)" "unprognostic (2.47e-2)" "unprognostic (2.08e-1)" "unprognostic (1.97e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (7.72e-3)" "unprognostic (3.11e-1)" "unprognostic (1.90e-2)" "prognostic favorable (4.83e-4)" "unprognostic (4.30e-1)" "unprognostic (5.10e-3)" "unprognostic (1.81e-1)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (1.81e-3)" 19.4 20.3 11.1 13.2 9.2 25.7 20.2 3.2 16.8 23.8 2.2 24.5 14.9 23.4 2.0 21.6 23.9 8.0 23.6 10.5 2.9 23.0 23.5 19.9 15.6 11.2 6.5 28.0 31.2 9.0 25.1 9.5 6.2 24.9 4.1 4.7 21.3 10.0 56.0 23.8 24.0 5.4 2.9 26.6 22.8 47.9 8.2 22.4 25.8 11.6 6.3 22.3 19.5 8.8 63.9 54.4 20.8 54.2 15.0 11.5 72.3 26.5 14.6 20.1 17.6 60.3 48.3 34.1 27.2 19.1 40.4 64.6 11.8 31.5 5.6 16.7 64.8 24.3 80.3 40.5 17.4 42.6 35.0 15.5 14.6 20.7 14.5 12.0 22.1 47.5 68.8 26.5 12.4 77.1 24.2 115.9 114.0 23.3 48.2 60.4 23.6 34.9 9.6 47.7 39.2 96.4 38.1 68.8 24.1 11.9 54.7 42.2 41.3 32.8 92.8 27.6 44.1 55.0 31.6 33.6 36.8 36.2 68.7 2.0 0.9 1.0 1.4 0.6 0.9 0.8 1.1 1.2 1.2 2.7 0.6 0.9 0.7 1.0 0.6 0.6 1.5 0.8 11.1 9.2 3.2 16.8 10.5 2.9 11.2 6.5 6.2 2.9 8.2 8.8 16.5 12.8 25.8 19.9 14.0 5.9 4.9 11.1 9.6 34.7 20.7 17.4 52.0 14.3 11.5 11.0 25.0 12.9 14.6 44.6 0.0 16.3 23.2 21.4 15.2 18.3 18.0 5.9 22.4 23.6 13.3 15.8 30.1 27.4 1.3 43.6 15.4 26.3 15.0 48.8 14.5 23.4 12.2 19.8 8.1 41.4 13.4 12.8 5.4 12.2 12.6 14.9 7.2 12.5 11.0 19.9 21.7 15.4 17.9 9.1 28.8 12.9 13.7 36.1 26.3 16.6 15.7 20.8 11.6 13.3 8.0 15.2 12.2 23.5 29.3 6.1 ISG15 "G1P2, IFI15, UCRP" ENSG00000187608 "ISG15 ubiquitin like modifier" P05161 1 1001138-1014540 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 320.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 497.1;Paneth cells: 403.1;Proximal enterocytes: 461.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 1460.2;BJ hTERT+ SV40 Large T+ RasG12V: 1466.7;HeLa: 501.4;SK-MEL-30: 487.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004627 Approved "Secreted to blood" NA NA 5000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA004627: AB_1079152" "unprognostic (3.65e-1)" "unprognostic (1.06e-1)" "unprognostic (1.12e-2)" "unprognostic (4.62e-2)" "unprognostic (3.96e-3)" "unprognostic (1.38e-1)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (3.78e-3)" "unprognostic (2.07e-3)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.11e-10)" "unprognostic (4.55e-2)" "unprognostic (4.13e-2)" "unprognostic (1.12e-2)" "unprognostic (7.46e-2)" 46.8 24.3 42.9 36.9 39.8 136.1 39.0 42.0 49.9 79.0 32.6 47.0 42.5 29.6 3.9 24.0 19.9 31.3 55.4 38.3 36.8 73.2 113.5 59.9 29.7 63.2 42.7 17.6 18.9 8.8 40.3 44.8 63.8 28.1 6.9 1.1 320.4 14.1 15.9 13.4 34.8 18.2 134.8 75.3 31.3 10.5 48.7 48.5 34.7 8.1 11.6 29.2 25.7 38.3 58.1 8.5 4.4 38.2 6.0 11.8 33.2 39.5 95.7 1460.2 1466.7 95.6 91.7 51.4 282.0 33.4 248.2 36.1 4.5 17.3 22.7 58.2 23.7 24.3 501.4 65.2 53.8 15.4 94.5 24.6 5.6 92.7 1.8 4.8 46.1 67.7 14.1 27.4 12.0 282.3 50.0 253.5 4.7 36.3 315.3 85.7 11.0 26.1 19.2 18.0 2.0 1.8 77.1 12.6 487.0 1.9 2.9 29.8 25.8 28.5 27.4 13.2 8.7 35.5 19.6 39.6 27.9 60.2 2.7 508.7 278.6 871.3 228.3 425.4 295.5 259.1 258.6 251.7 174.8 215.7 165.2 191.1 663.3 276.7 381.1 59.4 509.7 217.6 42.9 39.8 42.0 49.9 38.3 36.8 63.2 42.7 63.8 134.8 48.7 38.3 240.1 38.5 17.5 1.6 71.8 44.6 47.9 83.7 9.1 2.0 29.3 21.5 24.3 25.8 61.8 46.0 0.0 24.2 213.7 289.1 5.9 134.1 3.5 65.5 66.1 200.5 35.2 8.0 0.6 280.4 497.1 84.5 25.0 95.4 60.9 113.8 70.6 58.2 273.6 0.0 2.2 104.9 63.1 62.0 273.8 14.0 32.9 170.4 88.9 13.1 132.5 21.2 134.9 2.5 0.3 192.0 403.1 41.3 48.7 39.3 461.3 32.1 50.7 3.2 98.6 15.4 179.1 6.2 7.3 7.9 36.9 32.3 169.4 63.0 39.5 55.4 IST1 "CHMP8, KIAA0174" ENSG00000182149 "IST1 factor associated with ESCRT-III" P53990 16 71845996-71931199 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041802, HPA054532" Approved Supported Vesicles NA NA 270000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041802: AB_10794491, HPA054532: AB_2682517" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-3)" "unprognostic (2.04e-2)" "unprognostic (3.13e-3)" "unprognostic (2.11e-2)" "unprognostic (4.49e-2)" "unprognostic (3.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "prognostic favorable (4.55e-4)" "unprognostic (1.64e-2)" "unprognostic (7.88e-3)" "unprognostic (8.43e-3)" "prognostic favorable (8.88e-4)" 47.7 44.1 43.2 38.8 49.7 81.0 50.5 46.2 50.6 49.0 43.9 68.3 52.4 55.9 42.4 50.5 61.4 46.8 50.4 42.9 45.3 68.7 37.9 50.0 64.3 47.2 47.6 60.0 46.9 90.4 57.2 60.1 47.1 45.7 62.9 32.4 52.0 45.8 64.1 52.5 52.0 60.8 45.5 50.6 52.5 47.4 46.1 62.2 59.4 80.8 81.6 53.0 44.3 53.8 57.0 81.9 113.3 73.2 110.7 77.9 95.7 70.0 87.1 95.2 98.9 90.1 77.1 80.5 84.2 81.2 67.7 83.8 112.0 74.2 120.4 53.7 54.1 68.1 46.8 146.9 83.8 66.9 91.9 92.7 100.8 85.5 81.6 94.8 120.6 74.8 94.5 28.7 99.5 94.9 87.4 55.6 129.7 92.7 50.6 135.7 62.0 99.1 78.5 81.8 85.0 63.3 77.2 40.3 63.9 138.2 73.7 82.2 60.7 71.8 70.9 44.5 55.9 75.0 145.5 226.7 60.7 59.2 88.6 234.9 195.1 243.5 158.7 185.4 172.6 179.1 150.6 166.9 180.1 178.5 159.6 150.1 300.0 193.7 185.1 124.9 244.9 293.9 43.2 49.7 46.2 50.6 42.9 45.3 47.2 47.6 47.1 45.5 46.1 53.8 59.7 48.1 51.8 39.8 57.1 70.1 41.2 49.8 39.9 29.2 69.1 50.0 43.9 60.1 48.1 46.0 25.0 56.7 68.4 130.6 35.2 47.1 18.4 50.0 52.8 55.4 75.4 30.7 35.5 41.7 44.3 48.1 42.3 70.1 61.4 55.1 61.1 40.8 53.4 21.9 41.6 76.3 46.8 81.1 73.8 22.5 41.0 57.2 42.7 38.4 75.9 22.2 51.5 34.2 59.7 58.1 88.4 47.8 45.2 51.5 82.2 52.4 56.2 30.3 59.2 45.3 44.4 52.4 57.3 34.4 70.0 65.7 51.8 31.3 57.6 66.4 ISX RAXLX ENSG00000175329 "Intestine specific homeobox" Q2M1V0 22 35066136-35087387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "intestine: 37.5" "Group enriched" "Detected in some" 32 "Distal enterocytes: 24.2;Enteroendocrine cells: 19.4;Intestinal goblet cells: 16.0;Paneth cells: 19.4;Proximal enterocytes: 32.7;Undifferentiated cells: 23.8" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "CACO-2: 1.6;Hep G2: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA060328 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA060328: AB_2684254" "unprognostic (5.02e-2)" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "unprognostic (3.33e-1)" "unprognostic (3.86e-1)" "unprognostic (2.55e-1)" 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.6 37.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 26.0 0.0 0.0 0.0 0.0 0.0 27.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.2 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.1 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 23.8 0.0 ITM2C "BRI3, BRICD2C, E25, hRPC.1050_D_4, ITM3" ENSG00000135916 "Integral membrane protein 2C" Q9NQX7 2 230864639-230879248 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.2;intestine: 707.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2610.8;Intestinal goblet cells: 884.1;Paneth cells: 2076.6;Plasma cells: 1010.4;Undifferentiated cells: 843.5" "Cancer enhanced" "Detected in all" "glioma: 496.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 2464.2" "Lineage enriched" "Detected in all" 8 "dendritic cells: 2464.2" "Cell line enhanced" "Detected in many" "EFO-21: 517.7;NB-4: 599.8;RPMI-8226: 482.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 29000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.50e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (3.74e-1)" "unprognostic (6.03e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (4.44e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-2)" "unprognostic (1.04e-1)" "unprognostic (2.08e-1)" "unprognostic (4.92e-2)" "unprognostic (1.93e-1)" "unprognostic (2.70e-2)" "unprognostic (2.52e-2)" 42.5 89.0 861.0 116.0 900.6 109.6 31.4 710.8 1106.2 116.8 553.9 707.6 80.2 103.5 40.0 84.4 58.6 54.0 57.4 854.3 996.3 177.3 36.7 45.3 78.2 928.0 960.3 78.1 80.3 105.5 288.4 108.8 800.9 103.4 539.0 118.3 72.3 110.2 22.4 20.4 329.3 95.3 909.4 117.5 87.5 22.1 1082.7 178.6 52.9 33.8 72.1 124.2 74.9 840.3 34.1 67.0 215.6 170.6 27.2 15.3 68.8 176.0 191.6 92.5 144.2 89.7 46.8 0.4 517.7 126.3 94.9 16.8 127.2 25.6 58.1 328.3 109.0 44.7 33.6 119.1 96.0 81.1 180.9 131.4 24.7 83.6 8.2 33.8 3.5 76.8 43.6 108.3 35.5 53.0 59.3 599.8 263.5 184.0 58.8 85.2 37.0 482.9 123.5 200.8 11.8 329.4 85.8 10.3 207.4 220.7 17.0 455.6 2.9 39.6 114.4 70.5 50.0 0.7 9.1 4.6 124.6 70.1 336.5 76.5 3.6 291.0 12.5 1.8 33.2 185.2 39.7 33.1 68.9 94.7 38.1 31.6 6.9 52.0 0.6 2464.2 64.2 50.0 861.0 900.6 710.8 1106.2 854.3 996.3 928.0 960.3 800.9 909.4 1082.7 840.3 26.3 6.4 10.8 155.7 167.8 24.1 49.7 9.3 29.0 428.1 24.4 40.0 20.5 61.5 16.5 138.0 252.3 95.7 483.6 2610.8 27.4 123.0 0.8 43.0 34.0 36.2 408.3 8.4 49.3 39.5 63.4 94.9 21.4 45.6 183.9 41.6 16.4 14.8 80.1 101.0 63.3 884.1 12.2 7.5 108.9 3.4 54.3 26.0 202.7 27.2 70.9 225.9 3.1 107.5 17.8 46.2 2076.6 69.2 1010.4 52.9 666.0 23.7 16.5 101.1 138.1 30.9 108.6 4.8 20.5 3.8 14.9 57.6 75.3 37.9 843.5 97.7 JOSD2 SBBI54 ENSG00000161677 "Josephin domain containing 2" Q8TAC2 19 50505998-50511220 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (8.77e-2)" "unprognostic (3.09e-2)" "unprognostic (2.59e-1)" "unprognostic (1.57e-2)" "unprognostic (7.25e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (3.63e-2)" "unprognostic (2.41e-1)" "unprognostic (5.68e-2)" "unprognostic (1.75e-2)" "unprognostic (6.49e-2)" "unprognostic (2.42e-3)" "unprognostic (8.05e-2)" "unprognostic (2.04e-1)" "unprognostic (6.05e-2)" "unprognostic (9.34e-2)" 39.7 33.4 30.1 10.6 37.4 13.2 34.1 37.7 48.1 38.3 20.5 40.5 16.7 37.9 2.5 49.1 31.8 5.8 44.3 27.3 32.0 37.6 48.1 29.0 6.7 41.0 34.8 29.6 26.8 11.3 28.2 8.0 38.2 32.5 2.8 1.5 26.5 8.2 50.2 37.0 29.5 5.8 35.0 32.8 37.4 18.6 35.0 5.5 40.5 7.9 4.0 37.9 38.9 44.8 38.5 65.7 0.3 18.2 20.4 23.6 12.5 46.8 15.9 12.1 12.9 11.4 26.8 12.2 26.7 16.6 14.6 24.8 1.9 20.2 3.2 54.0 31.3 11.7 12.2 5.8 25.5 3.2 39.1 26.1 17.7 7.8 6.2 15.5 11.4 12.8 15.7 27.2 12.6 27.9 13.3 15.6 4.6 23.9 67.4 3.7 31.1 21.6 11.8 36.8 11.0 29.4 14.0 32.8 40.8 1.5 27.1 19.7 27.5 21.0 25.9 27.6 27.0 30.2 26.1 4.2 59.5 15.7 41.4 55.4 95.3 95.0 45.0 93.8 38.6 24.1 41.9 46.1 70.1 25.1 29.9 33.3 16.2 31.9 70.0 50.6 51.6 48.9 30.1 37.4 37.7 48.1 27.3 32.0 41.0 34.8 38.2 35.0 35.0 44.8 42.8 6.4 1.7 6.2 18.4 31.0 45.4 83.2 38.1 11.1 45.3 48.0 3.1 47.1 30.1 33.1 0.0 39.5 30.0 153.4 66.5 88.3 12.3 25.4 61.4 30.7 16.8 21.0 3.1 86.3 92.8 47.3 57.6 36.2 5.7 52.5 47.5 56.3 93.5 16.8 2.8 67.8 50.8 70.6 48.8 34.6 89.2 59.4 78.2 3.7 94.1 32.9 30.9 3.0 21.7 120.8 103.2 97.8 21.4 26.3 157.8 106.6 63.0 10.0 52.6 26.2 52.7 32.0 18.4 58.5 45.9 41.3 33.6 48.9 51.8 57.0 KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 197.1;stomach 1: 98.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 47.6;Microglial cells: 71.2;Undifferentiated cells: 57.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 33.4;OE19: 41.4;RPMI-8226: 23.2;U-266/70: 11.5;U-937: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018656, HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Plasma membrane" "CAB018656: AB_2131551, HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" 5.4 197.1 2.1 9.0 2.4 14.2 3.0 2.4 2.6 16.5 5.7 22.6 47.8 2.9 14.1 2.9 8.9 19.5 28.4 2.6 2.6 25.3 1.8 15.9 5.0 4.1 3.1 1.4 61.2 21.4 5.5 7.6 3.9 6.1 15.2 0.7 20.0 50.2 1.0 1.2 39.7 3.1 4.0 8.2 98.9 1.6 4.2 3.6 71.6 1.6 2.9 14.7 1.6 4.4 0.0 0.1 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 2.6 1.9 5.2 0.0 0.4 0.1 0.7 0.0 0.0 0.4 1.3 0.0 3.7 0.4 0.3 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.7 1.3 41.4 0.2 0.1 0.0 23.2 8.0 2.7 0.7 5.6 0.7 0.0 0.0 0.5 0.2 10.3 0.0 0.0 0.3 0.2 0.0 11.5 0.0 0.0 0.0 13.4 0.0 0.7 3.1 3.1 0.0 1.8 0.0 0.8 0.4 0.1 3.8 0.3 1.0 1.2 3.3 0.0 2.8 1.3 0.3 1.0 2.1 2.4 2.4 2.6 2.6 2.6 4.1 3.1 3.9 4.0 4.2 4.4 7.1 3.2 12.9 0.3 8.4 0.6 8.0 4.2 0.0 1.7 6.1 1.8 18.6 14.3 7.1 29.5 0.0 1.1 0.3 34.0 15.6 23.2 2.0 3.3 0.4 6.3 6.6 0.4 13.7 21.7 1.4 1.0 23.4 4.9 19.7 47.6 9.3 1.1 17.3 0.0 20.0 26.1 8.2 25.4 15.9 0.9 0.3 19.6 1.8 71.2 11.0 0.5 1.0 43.7 34.9 15.3 20.2 0.0 6.4 5.2 30.9 2.0 4.4 0.5 6.6 0.4 1.7 0.2 0.2 0.1 1.0 2.1 4.0 16.6 57.8 20.4 KCTD5 FLJ20040 ENSG00000167977 "Potassium channel tetramerization domain containing 5" Q9NXV2 16 2682523-2709030 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 62.6" "Group enriched" "Detected in all" 5 "dendritic cells: 62.6;granulocytes: 16.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.48e-2)" "unprognostic (1.87e-1)" "unprognostic (6.72e-2)" "unprognostic (5.15e-3)" "unprognostic (1.60e-1)" "unprognostic (9.95e-3)" "unprognostic (1.47e-3)" "unprognostic (1.45e-3)" "unprognostic (3.74e-1)" "unprognostic (1.52e-1)" "unprognostic (2.43e-3)" "unprognostic (8.21e-2)" "unprognostic (4.06e-3)" "unprognostic (2.15e-2)" "unprognostic (5.52e-3)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" 11.8 12.0 14.0 15.4 14.9 14.8 10.4 14.5 15.8 14.5 11.2 23.3 16.8 10.7 6.5 34.4 9.8 11.0 11.3 13.4 13.5 10.3 17.8 12.0 21.1 15.8 14.8 9.8 9.8 8.2 10.8 11.8 15.0 10.6 15.5 6.4 15.1 6.7 16.1 19.0 17.6 8.3 15.6 18.1 16.5 13.0 15.2 15.7 8.8 10.5 16.6 14.9 16.8 16.0 46.9 27.2 23.0 33.6 17.0 20.1 25.9 37.3 21.2 48.1 37.6 32.2 61.9 39.4 26.8 36.3 27.7 40.2 32.5 37.3 24.4 32.0 27.2 41.1 16.0 40.7 33.1 41.1 53.9 21.5 37.6 43.1 38.2 24.6 22.4 40.1 41.2 44.3 29.5 54.6 49.5 41.2 36.2 30.5 48.4 64.7 30.3 73.8 24.2 15.8 38.3 35.2 47.6 48.3 43.8 14.7 40.6 40.1 27.1 60.2 33.0 38.0 44.6 39.9 27.5 58.7 24.3 36.9 47.5 1.1 7.2 16.5 5.1 7.0 4.6 5.4 4.4 6.0 11.5 7.4 4.3 4.8 3.8 6.3 7.0 62.6 4.3 4.3 14.0 14.9 14.5 15.8 13.4 13.5 15.8 14.8 15.0 15.6 15.2 16.0 13.3 9.6 5.9 2.9 19.5 26.9 13.3 7.3 12.5 10.3 14.8 14.4 8.6 5.7 5.6 3.7 2.1 21.5 55.6 46.3 7.9 17.8 1.2 10.0 11.7 10.1 9.0 16.6 5.2 11.8 27.2 9.7 31.6 17.4 4.5 6.4 4.6 8.3 21.1 18.5 4.7 22.3 8.2 27.7 15.4 2.8 7.5 24.0 17.8 8.4 22.1 16.3 12.3 9.0 9.7 30.5 29.6 8.2 13.0 11.3 18.3 7.7 5.6 8.5 13.1 11.0 12.9 5.8 16.6 17.9 31.3 39.4 17.0 9.4 22.7 18.4 KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.7;hTCEpi: 103.0;RT4: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" 7.9 93.0 14.6 7.0 10.7 1.2 24.3 1.8 15.6 14.5 27.1 42.5 51.7 10.1 12.2 76.7 23.5 16.0 5.1 12.4 6.5 43.9 12.0 18.2 1.2 5.2 5.5 22.3 70.7 37.8 9.1 8.4 4.3 40.9 30.9 1.2 68.3 20.2 3.1 74.1 45.9 6.7 4.2 1.4 61.8 5.1 7.7 8.2 39.4 3.2 12.1 22.2 28.1 8.8 65.7 33.6 5.4 9.3 2.4 4.6 24.6 7.9 15.3 8.9 8.7 37.0 125.7 0.2 32.3 11.6 26.5 95.1 10.3 67.8 4.6 0.2 13.4 13.6 49.4 30.4 4.0 0.2 33.3 1.7 103.0 23.6 28.2 40.1 18.6 2.7 20.1 0.4 4.3 54.3 0.3 0.6 11.0 56.3 20.9 8.7 6.7 16.7 85.8 117.5 4.6 4.7 49.5 70.1 9.7 33.7 74.7 4.3 17.6 14.9 39.3 13.7 17.3 0.8 0.3 0.3 15.2 2.3 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 10.7 1.8 15.6 12.4 6.5 5.2 5.5 4.3 4.2 7.7 8.8 5.7 12.8 56.9 5.5 0.6 73.9 37.0 52.7 59.2 0.6 69.8 42.3 3.8 72.9 52.0 27.6 2.1 15.6 1.5 154.4 9.8 47.3 4.2 54.7 5.6 8.7 28.9 1.3 10.2 66.7 5.2 6.7 51.0 50.2 27.8 10.2 4.6 10.6 2.9 0.0 5.2 54.0 48.8 0.8 6.5 5.1 8.7 2.2 7.2 3.7 2.4 0.8 0.0 2.0 0.4 60.7 64.6 4.9 0.3 80.9 84.7 14.8 60.7 0.1 6.6 3.1 7.5 3.8 2.7 59.7 83.1 7.9 2.1 59.9 65.4 99.6 KIF16B "C20orf23, dJ971B4.1, FLJ20135, SNX23" ENSG00000089177 "Kinesin family member 16B" Q96L93 20 16272104-16573448 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 38.1" "Low region specificity" "Detected in all" HPA051198 Approved Uncertain Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA051198: AB_2681385" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-1)" "unprognostic (3.92e-2)" "unprognostic (2.44e-1)" "unprognostic (6.32e-3)" "unprognostic (7.85e-2)" "unprognostic (2.38e-1)" "unprognostic (5.34e-2)" "unprognostic (3.95e-2)" "unprognostic (5.52e-1)" "prognostic favorable (7.61e-6)" "unprognostic (4.04e-2)" "unprognostic (2.78e-1)" "unprognostic (4.74e-2)" "unprognostic (1.61e-2)" 10.1 27.4 5.4 6.4 6.1 5.9 15.8 4.9 8.6 6.3 3.6 24.5 16.7 6.1 12.5 9.4 5.1 8.3 11.5 4.3 6.4 18.1 11.7 8.8 5.3 6.4 5.4 12.8 6.5 31.5 5.2 4.8 6.0 7.3 19.1 9.7 7.3 10.8 17.1 11.9 20.8 7.4 3.9 8.2 12.8 5.1 6.3 5.9 11.1 13.1 4.7 7.9 6.2 7.9 7.7 19.3 9.1 8.3 6.8 5.0 8.8 7.4 4.5 4.6 5.0 9.5 18.5 10.7 4.7 8.0 12.7 6.9 10.8 11.0 6.8 5.7 6.2 4.8 4.7 17.6 4.2 0.0 10.5 8.0 21.4 5.5 10.6 7.0 1.8 8.1 8.7 0.0 7.5 12.2 0.1 2.0 2.6 24.9 8.7 8.1 7.2 18.9 7.2 12.2 4.0 7.9 8.0 38.1 23.9 10.7 11.3 6.3 3.7 7.0 5.9 11.4 3.4 0.0 4.9 3.2 6.6 3.2 14.3 0.0 2.1 0.5 2.0 1.7 2.7 2.7 2.2 1.5 3.4 2.6 2.3 1.7 0.2 4.5 1.8 1.6 1.6 1.7 5.4 6.1 4.9 8.6 4.3 6.4 6.4 5.4 6.0 3.9 6.3 7.9 13.1 19.2 31.7 54.9 9.8 19.1 16.1 11.0 37.5 8.7 30.5 16.0 29.2 4.3 14.8 5.5 18.8 15.7 7.7 60.6 3.9 6.5 12.6 13.2 14.2 13.6 23.4 5.0 67.6 12.3 5.5 15.1 18.3 20.8 9.5 13.6 12.5 15.9 19.1 37.0 84.2 38.9 4.1 12.2 35.7 9.8 11.5 19.8 10.6 59.0 4.9 8.6 10.3 60.3 94.1 13.3 40.9 14.7 6.9 11.1 36.8 21.1 11.6 11.5 6.6 22.7 13.4 12.9 15.0 26.3 22.4 37.5 9.4 12.9 24.8 19.3 KIFC2 ENSG00000167702 "Kinesin family member C2" Q96AC6 8 144466043-144474202 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 113.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 59.8;Gastric mucus-secreting cells: 38.7;Inhibitory neurons: 39.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029264 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA029264: AB_10609999" "unprognostic (2.03e-1)" "unprognostic (1.28e-3)" "unprognostic (3.87e-3)" "unprognostic (4.12e-3)" "unprognostic (4.28e-2)" "unprognostic (1.48e-1)" "unprognostic (2.20e-2)" "unprognostic (3.41e-2)" "unprognostic (2.12e-1)" "unprognostic (9.95e-2)" "unprognostic (2.39e-2)" "unprognostic (4.48e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" "unprognostic (8.13e-2)" "unprognostic (2.71e-2)" 12.3 17.2 68.7 6.2 78.3 7.2 14.0 58.3 113.7 24.5 33.2 26.5 11.9 11.4 6.7 45.0 15.3 6.1 10.1 74.7 42.9 32.9 20.6 17.2 7.3 54.9 41.1 13.0 24.9 9.6 45.0 3.2 54.6 31.5 6.3 3.8 19.1 8.0 4.2 75.0 24.4 2.5 35.7 27.6 19.7 25.8 46.4 5.4 24.2 1.7 4.8 22.2 31.8 63.9 13.5 12.7 6.1 13.2 8.7 5.2 13.2 5.3 6.4 4.7 4.6 4.9 18.1 11.6 3.6 5.0 7.9 24.2 6.1 8.1 2.0 10.2 3.7 8.6 34.5 6.6 11.1 2.6 23.4 6.7 28.3 4.7 6.1 21.8 3.0 14.7 7.0 15.9 3.6 25.4 10.3 7.1 0.9 16.5 15.2 24.1 0.3 8.8 19.9 23.1 18.4 16.4 6.2 19.3 6.9 4.3 50.4 5.0 7.6 9.0 22.9 9.4 7.7 6.3 2.9 3.9 17.6 12.3 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.7 78.3 58.3 113.7 74.7 42.9 54.9 41.1 54.6 35.7 46.4 63.9 3.7 9.6 11.3 35.3 4.9 6.0 3.0 2.1 6.2 16.2 7.9 5.8 0.8 7.2 5.2 14.7 6.2 2.0 12.1 29.1 1.9 3.5 13.2 6.8 4.4 2.0 23.4 3.2 59.8 1.4 2.0 2.0 38.7 13.8 8.2 3.3 2.5 8.7 2.7 15.2 39.7 12.2 0.0 5.3 9.1 8.0 7.8 6.4 3.6 12.2 3.5 7.5 3.1 8.5 6.9 2.2 18.5 3.0 7.0 3.4 11.3 5.1 4.5 4.6 0.0 1.8 2.9 7.3 7.5 10.6 11.4 3.0 8.0 6.6 18.0 3.3 KLLN killin ENSG00000227268 "Killin, p53 regulated DNA replication inhibitor" B2CW77 10 87859158-87863533 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 4.5" "Cell type enhanced" "Detected in many" "granulocytes: 5.7;Sertoli cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "JURKAT: 5.0;Karpas-707: 5.1" HPA074502 Supported Nucleoplasm,Nucleoli No No "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Nucleoli "HPA074502: AB_2686695" "unprognostic (4.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (3.71e-1)" "unprognostic (6.53e-2)" "unprognostic (1.37e-1)" "unprognostic (3.59e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.57e-2)" "unprognostic (4.79e-4)" "unprognostic (1.38e-2)" "unprognostic (1.00e-1)" "unprognostic (9.02e-4)" "unprognostic (1.60e-1)" 1.0 0.7 1.0 0.6 0.7 0.5 0.6 1.5 1.6 0.7 0.6 0.9 0.4 0.5 1.0 0.4 1.4 0.4 0.5 0.7 0.9 0.9 0.9 0.4 0.8 0.5 0.6 0.4 0.2 0.5 0.5 0.6 0.6 0.4 0.8 1.0 0.3 0.5 4.5 0.4 0.4 0.5 0.3 0.8 0.6 1.0 0.6 1.0 0.7 0.5 0.8 0.3 0.3 1.5 0.8 1.0 1.1 0.7 0.5 0.3 0.8 0.7 0.9 0.5 0.7 0.6 2.6 2.0 0.3 0.2 0.5 0.9 0.7 0.8 0.4 0.5 0.3 0.7 1.5 0.6 0.6 1.4 0.5 0.6 0.8 0.7 0.8 0.9 0.3 5.0 0.4 5.1 0.5 1.8 4.1 1.6 0.4 0.6 0.5 2.6 0.1 2.6 0.4 0.8 0.4 1.0 0.9 0.6 0.1 0.7 1.6 1.2 0.3 0.5 0.3 0.9 0.3 2.9 3.3 2.9 0.9 2.9 0.6 1.6 0.3 0.6 0.2 0.5 0.4 0.4 0.3 0.3 0.3 0.5 0.4 0.3 2.5 0.6 0.8 0.5 0.2 0.2 1.0 0.7 1.5 1.6 0.7 0.9 0.5 0.6 0.6 0.3 0.6 1.5 0.6 0.0 0.0 0.3 0.5 0.1 0.3 0.2 0.6 1.7 1.0 1.3 2.7 1.5 1.3 0.0 0.0 0.7 2.0 3.0 0.0 0.2 3.9 0.8 0.9 0.6 0.0 0.8 0.4 0.2 0.4 1.1 3.6 0.4 5.7 0.3 0.7 0.4 0.3 3.3 0.5 1.8 0.0 1.3 0.0 2.0 0.0 0.6 0.0 0.0 0.3 1.6 0.0 0.0 0.1 0.3 2.5 0.0 0.2 0.3 1.8 1.9 2.3 1.0 6.6 1.1 2.9 0.3 1.2 0.6 0.4 0.5 0.7 0.3 1.3 0.2 KRCC1 FLJ22333 ENSG00000172086 "Lysine rich coiled-coil 1" Q9NPI7 2 88027205-88064252 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045618, HPA052666" Approved Approved Nucleoli,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoli "HPA045618: AB_10960406, HPA052666: AB_2681907" "unprognostic (7.37e-3)" "unprognostic (1.30e-1)" "unprognostic (2.09e-1)" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (2.59e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "unprognostic (4.83e-2)" "unprognostic (2.22e-1)" "unprognostic (6.04e-2)" "unprognostic (1.99e-2)" "unprognostic (2.60e-1)" "unprognostic (1.91e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-3)" 28.2 21.0 20.1 28.7 22.8 10.1 38.4 21.7 28.0 33.0 20.7 45.9 32.0 23.9 41.7 32.2 27.1 22.2 31.7 19.9 21.6 31.9 43.6 21.9 38.0 23.2 22.0 24.6 28.6 34.1 15.7 21.9 23.7 25.2 43.8 14.5 24.8 26.0 29.1 25.8 35.7 22.9 21.8 30.7 27.2 15.2 21.7 31.5 33.2 34.6 32.4 24.4 24.9 24.9 29.4 17.8 27.4 20.1 64.1 75.3 20.2 45.5 50.3 23.7 23.1 1.6 38.5 41.4 16.0 28.9 36.1 14.8 6.3 9.4 26.7 43.7 8.7 8.0 4.4 2.8 46.7 12.2 5.5 38.0 46.3 15.9 33.7 61.9 27.1 32.9 11.5 20.2 51.7 25.0 14.1 16.9 20.9 42.3 11.8 28.3 5.0 4.5 36.0 15.8 21.1 21.3 17.3 23.7 54.8 20.1 16.7 49.2 38.2 28.0 2.1 46.5 14.5 45.3 33.6 32.5 30.1 32.0 67.5 59.4 21.6 77.7 18.8 23.8 21.7 36.6 23.0 23.2 25.7 32.5 25.8 21.0 35.8 31.6 21.5 22.5 34.3 16.8 20.1 22.8 21.7 28.0 19.9 21.6 23.2 22.0 23.7 21.8 21.7 24.9 24.2 35.3 41.7 29.4 61.8 33.0 32.6 49.9 53.5 11.9 50.9 50.9 41.3 40.0 49.0 35.0 2.1 46.1 24.8 109.1 60.7 50.5 16.7 34.4 37.8 31.6 41.6 28.2 14.5 70.9 16.3 42.5 17.3 30.9 43.1 28.4 37.9 59.5 48.6 10.1 13.9 56.8 26.4 40.3 39.8 5.3 47.8 38.8 28.4 44.0 53.6 35.9 58.7 34.7 53.5 51.4 79.6 43.2 29.6 62.6 60.4 76.0 62.6 5.4 19.7 40.3 29.7 41.0 20.7 45.4 42.6 41.9 37.2 32.2 72.4 26.4 KRT12 K12 ENSG00000187242 "Keratin 12" Q99456 17 40861303-40867223 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 1.0" "Group enriched" "Detected in some" 5 "Distal enterocytes: 3.9;Paneth cells: 12.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055217, HPA055835" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055217: AB_2682742, HPA055835: AB_2682935" "unprognostic (1.89e-1)" "unprognostic (2.40e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-1)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.74e-2)" "unprognostic (5.52e-2)" "unprognostic (9.41e-3)" "unprognostic (3.49e-1)" "unprognostic (1.73e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-4)" "unprognostic (6.31e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 KRT20 "CK20, K20, MGC35423" ENSG00000171431 "Keratin 20" P35900 17 40875889-40885242 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 646.9" "Group enriched" "Detected in some" 6 "Distal enterocytes: 1328.5;Intestinal goblet cells: 421.7;Paneth cells: 1606.6;Proximal enterocytes: 1107.3" "Group enriched" "Detected in many" 6 "colorectal cancer: 159.5;stomach cancer: 52.7;urothelial cancer: 99.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000032, HPA024309, HPA024684, HPA027236" Enhanced Supported Cytosol NA NA 30000000 "Cluster 9: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB000032: AB_2133718, HPA024309: AB_1852220, HPA024684: AB_1852222, HPA027236: AB_1852224" "unprognostic (3.49e-1)" "unprognostic (3.13e-1)" "unprognostic (1.71e-1)" "unprognostic (6.38e-3)" "unprognostic (5.12e-2)" "unprognostic (2.66e-3)" "prognostic unfavorable (7.05e-4)" "unprognostic (2.63e-2)" "unprognostic (4.87e-3)" "unprognostic (2.37e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (5.71e-2)" "unprognostic (6.30e-2)" "unprognostic (7.27e-2)" 1.3 0.0 0.0 49.9 0.0 0.0 1.6 0.0 0.0 0.1 0.0 597.7 295.9 2.1 0.0 0.3 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 480.1 0.0 0.0 1.2 0.0 0.1 646.9 27.0 0.0 0.0 124.9 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1328.5 0.0 0.1 0.0 0.0 0.0 0.0 43.9 0.0 0.1 0.0 0.0 0.0 115.7 0.1 13.4 0.0 0.0 0.0 0.1 0.0 0.0 421.7 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1606.6 0.0 0.6 1.9 1107.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.6 0.0 160.4 1.4 KRTAP13-2 KAP13-2 ENSG00000182816 "Keratin associated protein 13-2" Q52LG2 21 30371390-30372271 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 12.8" "Group enriched" "Detected in some" 4 "Distal enterocytes: 31.1;Paneth cells: 27.0;Prostatic glandular cells: 11.0" "Cancer enhanced" "Detected in single" "prostate cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 1000000 "Cluster 61: Skin - Cornification" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.44e-2)" "unprognostic (5.68e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.8 0.0 0.0 0.0 0.0 12.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.1 0.0 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 5.4 KRTAP4-1 "KAP4.1, KAP4.10, KRTAP4-10" ENSG00000198443 "Keratin associated protein 4-1" Q9BYQ7 17 41184102-41185342 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 68 "skin 1: 26.6" "Cell type enhanced" "Detected in single" "Enteroendocrine cells: 1.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.1;A549: 1.7;CAPAN-2: 1.2;HDLM-2: 4.9;SCLC-21H: 1.2;SK-BR-3: 1.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.21e-1)" "unprognostic (3.57e-1)" "unprognostic (1.64e-2)" "unprognostic (2.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.49e-2)" "unprognostic (2.42e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 KRTAP5-2 "KRTAP5-8, KRTAP5.2" ENSG00000205867 "Keratin associated protein 5-2" Q701N4 11 1597177-1598294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.6;SCLC-21H: 2.8;SH-SY5Y: 1.2" NA NA "Cluster 61: Skin - Cornification" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.31e-2)" 0.0 0.3 0.2 0.1 0.1 0.0 0.0 1.9 0.8 0.0 0.0 0.2 0.5 0.1 0.3 0.0 0.1 0.5 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.1 0.0 0.6 0.6 0.0 0.1 9.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.2 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.1 KRTCAP3 KCP3 ENSG00000157992 "Keratinocyte associated protein 3" Q53RY4 2 27442366-27446481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 182.0;Proximal enterocytes: 168.7;Undifferentiated cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "MAIT T-cell: 6.8;memory B-cell: 4.5;memory CD4 T-cell: 5.6;memory CD8 T-cell: 2.6;naive B-cell: 6.4;naive CD4 T-cell: 6.6;naive CD8 T-cell: 2.7;T-reg: 4.4" "Group enriched" "Detected in many" 13 "B-cells: 6.4;T-cells: 6.8" "Cell line enhanced" "Detected in many" "A-431: 84.6;CAPAN-2: 122.5;OE19: 46.6;SCLC-21H: 60.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA047136, HPA060203" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA047136: AB_2679949, HPA060203: AB_2684221" "prognostic favorable (2.67e-5)" "unprognostic (5.93e-2)" "unprognostic (5.03e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" "unprognostic (7.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (9.43e-2)" "unprognostic (1.60e-2)" "unprognostic (1.44e-2)" "unprognostic (4.63e-2)" "unprognostic (1.04e-1)" "unprognostic (3.73e-3)" "unprognostic (3.79e-2)" "unprognostic (8.21e-2)" "unprognostic (9.42e-3)" 2.2 2.7 3.0 6.3 3.5 3.0 16.0 5.3 5.6 11.8 3.7 39.6 44.3 5.8 1.8 18.3 24.9 9.5 0.7 2.9 3.5 7.9 9.8 11.3 3.3 3.9 3.5 2.4 44.6 18.6 14.1 2.9 3.7 20.9 27.8 7.3 38.5 12.7 3.2 14.1 45.5 1.7 3.0 3.1 42.4 2.2 3.3 3.7 11.5 0.0 5.2 10.0 11.2 4.6 84.6 1.2 6.1 2.7 0.3 0.6 17.4 0.9 0.3 1.0 0.9 32.7 122.5 1.0 1.1 0.2 0.5 28.4 0.9 25.0 0.3 1.0 0.6 2.2 1.9 2.7 0.0 0.3 3.9 1.1 2.7 0.6 1.5 1.2 1.0 2.8 1.8 1.5 0.9 27.2 0.9 7.8 27.7 46.6 1.1 0.8 1.8 2.5 1.7 2.4 60.2 2.2 2.3 25.4 3.6 2.0 2.5 1.4 2.4 3.4 5.4 1.2 1.1 7.0 5.9 1.1 2.3 1.1 0.8 0.0 0.0 0.0 0.6 0.0 6.8 4.5 5.6 2.6 0.0 6.4 6.6 2.7 0.0 0.5 0.0 0.0 4.4 1.5 3.0 3.5 5.3 5.6 2.9 3.5 3.9 3.5 3.7 3.0 3.3 4.6 1.1 22.4 27.9 2.6 2.9 23.3 125.1 135.4 71.7 4.9 100.9 105.2 0.5 88.6 92.5 42.3 8.4 17.0 1.9 74.2 5.9 105.4 6.4 50.9 3.8 2.7 62.0 3.6 1.2 182.0 27.6 3.4 68.3 47.9 4.5 0.9 1.4 15.2 2.1 1.7 1.1 123.6 105.8 1.0 2.5 4.7 0.3 2.0 7.2 1.9 2.9 1.9 2.1 1.5 1.3 108.7 112.9 0.0 0.7 123.7 168.7 7.7 85.2 5.9 0.0 0.9 6.9 3.8 29.4 48.0 15.5 7.9 3.0 0.7 190.2 144.2 LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Distal enterocytes: 173.6;Granulosa cells: 77.3;Intestinal goblet cells: 44.2;Paneth cells: 35.8;Proximal enterocytes: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 56.0;ASC diff: 41.0;BEWO: 199.6;hTEC/SVTERT24-B: 41.7;SK-MEL-30: 38.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB010179 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" 0.7 0.0 2.0 0.2 1.5 0.0 1.6 1.9 1.1 0.8 0.5 0.1 0.0 0.9 1.4 0.1 0.2 0.0 0.2 2.0 2.0 2.9 0.1 0.3 0.0 2.0 2.8 1.4 1.1 0.0 1.0 0.1 2.1 0.2 0.0 0.4 1.3 0.6 0.0 0.2 0.0 0.3 2.2 0.1 0.0 5.9 3.0 0.1 2.5 0.0 0.0 0.3 0.2 2.9 0.0 0.0 56.0 0.0 41.0 36.5 199.6 2.0 9.8 9.9 21.5 24.4 0.0 0.0 0.5 3.4 8.0 0.1 0.0 7.3 4.1 0.0 3.2 0.0 11.8 0.0 4.8 0.0 0.0 31.1 1.1 41.7 23.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 2.8 0.0 0.0 38.4 11.6 0.0 0.0 0.0 7.5 20.5 4.2 0.1 0.0 0.0 0.0 3.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 1.9 1.1 2.0 2.0 2.0 2.8 2.1 2.2 3.0 2.9 2.6 6.4 0.0 90.8 0.0 0.0 0.8 0.8 0.6 0.5 2.3 7.2 1.9 4.3 0.0 0.0 0.0 4.1 0.0 173.6 0.0 0.0 1.6 4.1 0.6 0.2 1.2 0.0 1.4 0.5 3.1 4.2 0.0 4.3 0.0 77.3 0.0 0.1 0.9 0.0 1.7 44.2 0.0 0.0 0.0 3.7 0.0 0.2 0.0 15.0 0.0 3.4 0.0 4.0 1.8 0.0 35.8 0.0 0.0 1.0 47.5 1.4 0.1 0.3 0.0 0.6 3.4 0.4 2.5 0.3 0.0 4.8 0.2 4.6 16.5 0.3 LAMTOR4 C7orf59 ENSG00000188186 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4" Q0VGL1 7 100148907-100155944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 3294.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020998 Enhanced Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA020998: AB_1845762" "prognostic favorable (2.48e-4)" "prognostic favorable (6.08e-4)" "unprognostic (1.29e-2)" "unprognostic (1.14e-1)" "unprognostic (8.21e-3)" "unprognostic (6.11e-2)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (6.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.42e-3)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.45e-1)" "unprognostic (1.68e-2)" 145.5 144.7 207.2 92.8 215.4 194.6 143.4 221.1 260.4 148.0 204.4 180.6 89.4 116.7 65.9 117.5 123.1 97.7 167.4 205.7 212.3 188.5 139.1 128.0 159.0 222.1 211.3 142.7 124.2 126.7 162.7 68.1 213.3 160.8 105.8 39.9 116.8 76.2 137.5 478.7 151.0 69.0 217.6 251.9 162.2 86.6 215.8 104.8 133.8 106.0 85.5 145.8 126.7 224.1 105.9 250.9 130.2 165.4 135.2 154.9 105.7 62.1 151.0 113.1 138.9 116.9 165.7 169.1 204.7 94.2 205.7 108.9 124.0 160.0 48.1 172.4 353.2 135.2 245.0 205.4 127.4 106.4 187.1 187.3 155.4 118.5 145.6 125.7 174.9 155.3 129.9 264.4 156.1 501.0 104.0 424.7 138.7 291.1 199.9 107.4 107.1 302.8 129.1 126.9 91.6 169.0 114.3 265.8 211.3 99.0 107.1 207.0 118.3 107.1 158.6 223.7 101.7 159.1 231.2 324.2 171.0 293.5 155.9 1033.3 843.2 3121.0 299.6 795.1 251.1 541.8 377.5 312.8 570.0 475.4 381.8 307.2 3294.2 310.1 756.2 482.6 453.0 893.6 207.2 215.4 221.1 260.4 205.7 212.3 222.1 211.3 213.3 217.6 215.8 224.1 181.8 93.0 150.7 18.9 195.8 274.9 194.0 282.0 167.9 65.3 240.8 277.2 176.6 143.0 172.9 218.8 12.5 258.4 199.9 819.7 534.1 167.3 40.0 152.9 125.8 186.7 299.3 99.3 12.0 326.2 196.5 175.6 146.3 131.4 183.2 120.9 239.1 246.3 531.1 58.9 13.6 423.9 252.3 497.4 351.7 46.6 146.3 365.2 434.0 13.1 411.0 229.9 298.6 11.6 26.2 204.2 867.4 120.4 133.0 169.5 511.6 557.5 194.8 67.0 144.7 142.1 196.9 88.1 101.2 151.3 662.9 201.4 195.9 150.8 511.8 219.0 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;liver: 135.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1" "Cancer enhanced" "Detected in all" "liver cancer: 32.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.1" "Group enriched" "Detected in many" 45 "granulocytes: 11.1;monocytes: 4.8" "Cell line enhanced" "Detected in many" "Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol No NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626" "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favorable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 24.9 14.4 17.7 2.1 19.7 0.7 11.7 20.5 22.6 5.4 34.1 27.2 8.8 3.5 1.1 10.8 5.5 3.0 85.6 16.1 18.9 36.1 135.5 4.9 0.8 20.8 20.2 16.4 18.7 17.0 11.8 0.7 22.4 8.1 9.7 1.3 21.3 3.2 68.7 5.8 5.7 1.2 17.0 1.1 23.1 1.7 19.3 0.5 10.6 52.7 0.6 2.6 3.7 17.5 0.7 2.1 0.0 0.2 1.6 1.4 6.1 0.2 0.1 0.2 0.2 2.8 2.6 0.1 2.1 0.9 1.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.8 11.4 2.6 0.0 14.4 2.0 0.3 0.0 0.0 0.6 0.1 0.4 0.7 2.5 0.0 5.3 0.1 0.8 1.4 2.7 1.3 0.0 0.0 7.8 1.4 0.1 0.0 0.0 0.2 5.2 0.3 0.7 29.1 3.3 0.0 0.0 0.2 0.0 0.0 11.5 0.6 0.0 1.9 0.1 0.0 11.1 2.2 0.6 0.0 3.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 17.7 19.7 20.5 22.6 16.1 18.9 20.8 20.2 22.4 17.0 19.3 17.5 1.6 0.0 6.7 7.8 1.0 0.6 1.8 2.2 0.6 0.5 6.5 2.4 37.3 11.5 2.3 11.0 0.0 2.1 0.1 80.2 37.2 2.3 0.4 2.2 0.3 1.7 3.0 2.7 1.0 6.2 1.2 2.3 32.6 3.8 10.2 2.1 4.2 88.6 7.2 1.7 1.4 11.0 0.0 6.0 1.0 0.6 0.0 3.0 5.4 1.9 2.0 12.0 0.0 1.0 3.2 3.0 28.3 0.0 0.8 2.1 2.4 118.1 2.0 1.4 0.0 4.1 1.3 0.0 0.7 3.6 0.3 3.1 1.0 1.8 15.7 1.5 LEFTY1 "LEFTB, LEFTYB" ENSG00000243709 "Left-right determination factor 1" O75610 1 225886282-225911382 "Metabolic proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "intestine: 68.3;pancreas: 96.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 201.5;Glandular and luminal cells: 175.0;Intestinal goblet cells: 86.1;Paneth cells: 228.9;Undifferentiated cells: 301.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 44.8;endometrial cancer: 36.2;pancreatic cancer: 13.8;testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 51 "basophil: 17.0" "Lineage enriched" "Detected in single" 51 "granulocytes: 17.0" "Cell line enriched" "Detected in some" 6 "NTERA-2: 50.2" "HPA047883, HPA056210" Approved "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (2.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.26e-2)" "unprognostic (1.18e-2)" "unprognostic (1.83e-2)" "unprognostic (3.50e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (7.76e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (2.48e-6)" "unprognostic (2.78e-2)" "unprognostic (1.12e-1)" "unprognostic (2.01e-1)" "unprognostic (2.61e-2)" 0.3 0.2 2.1 7.8 2.1 0.0 0.4 1.8 2.7 1.4 1.3 68.3 0.2 0.5 6.9 0.1 0.6 0.0 0.4 2.1 1.9 1.7 0.9 0.3 0.0 1.6 1.7 4.1 96.9 0.0 1.0 0.2 1.7 0.9 32.4 0.8 1.5 3.3 0.4 0.2 2.9 0.8 1.6 0.3 1.4 0.8 1.9 0.0 0.1 0.1 0.1 1.5 0.2 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.3 0.0 0.0 0.0 4.5 0.1 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.2 0.0 0.0 0.0 5.4 0.6 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 2.1 2.1 1.8 2.7 2.1 1.9 1.6 1.7 1.7 1.6 1.9 1.9 0.2 0.0 0.0 0.7 1.0 0.4 1.6 0.0 0.0 1.8 0.2 0.3 0.1 14.3 0.0 0.0 0.0 0.0 0.0 51.7 1.9 20.1 1.8 201.5 9.9 0.3 31.5 0.0 2.3 29.6 0.1 1.6 0.0 175.0 0.0 1.6 0.0 0.2 0.0 0.0 2.3 86.1 0.0 0.0 0.0 3.9 1.5 2.1 0.0 0.0 0.0 0.9 0.0 1.5 0.2 0.5 228.9 1.9 0.0 0.8 0.7 6.0 0.0 1.4 0.0 0.0 0.6 2.5 4.2 0.0 0.0 0.0 1.0 1.3 301.0 1.3 LETM1 SLC55A1 ENSG00000168924 "Leucine zipper and EF-hand containing transmembrane protein 1" O95202 4 1811479-1856156 "Human disease related genes, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011029, HPA011100" Supported Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA011029: AB_1852804, HPA011100: AB_1852802" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (3.85e-2)" "unprognostic (5.04e-2)" "unprognostic (5.48e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.37e-3)" "unprognostic (1.87e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.77e-4)" "prognostic favorable (8.90e-4)" "unprognostic (8.06e-3)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (2.42e-1)" 13.6 16.3 14.3 7.9 13.7 7.7 10.8 11.7 14.6 8.2 10.8 20.3 13.9 8.4 3.2 23.8 8.0 4.5 19.6 13.4 13.2 13.3 16.4 8.9 7.0 12.7 13.5 9.2 12.5 11.4 8.8 4.9 11.9 8.4 10.7 4.5 9.6 4.2 18.7 15.9 11.7 5.1 12.2 10.7 13.8 14.5 15.0 25.7 10.7 10.9 7.9 8.4 10.6 11.6 22.9 38.1 11.6 36.1 17.4 12.2 20.7 22.1 10.7 21.8 16.9 35.5 24.7 37.5 15.4 23.3 34.0 22.7 29.8 31.2 13.2 25.1 31.1 38.4 30.9 25.6 22.6 39.3 30.3 19.9 22.0 24.9 21.8 10.1 19.0 22.6 51.5 22.9 15.3 25.1 57.3 44.7 30.5 24.7 43.2 32.4 16.2 21.9 17.0 31.3 29.5 26.0 25.2 31.5 13.3 10.0 29.7 20.3 28.8 24.8 14.8 21.1 37.3 19.8 32.7 29.3 22.0 33.8 20.2 3.9 3.7 2.0 5.8 5.0 5.7 4.2 4.9 4.9 4.1 3.6 3.2 4.6 0.5 5.9 5.1 12.9 4.2 2.1 14.3 13.7 11.7 14.6 13.4 13.2 12.7 13.5 11.9 12.2 15.0 11.6 12.2 16.0 11.5 15.0 19.2 40.0 40.7 13.4 8.0 19.4 19.7 10.5 23.3 11.5 14.0 27.6 33.3 17.5 24.9 116.1 31.3 25.5 32.2 9.1 19.4 16.7 15.6 20.4 14.3 31.3 22.6 17.0 32.1 14.7 10.2 17.9 16.1 33.3 21.5 15.2 12.4 29.5 12.2 18.4 19.8 45.1 20.2 13.0 19.6 4.7 13.9 12.7 28.8 9.5 13.2 42.4 52.7 16.6 17.8 58.8 48.8 46.1 5.6 28.4 13.1 23.8 16.1 54.2 44.4 25.2 51.1 15.2 16.7 21.9 53.2 48.4 LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1194.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4097.0;Paneth cells: 3445.9;Proximal enterocytes: 4397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 651.4;intermediate monocyte: 544.6;myeloid DC: 397.8;non-classical monocyte: 441.2;T-reg: 251.9" "Group enriched" "Detected in all" 13 "dendritic cells: 397.8;monocytes: 651.4;T-cells: 251.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 1169.3;CAPAN-2: 968.0;OE19: 1613.0;SK-MEL-30: 2329.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1900000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" 404.5 72.0 111.4 219.8 111.8 346.9 323.1 110.7 148.1 331.4 104.3 1194.1 691.9 162.3 53.8 437.8 223.1 273.0 246.2 110.3 109.4 120.0 27.3 356.1 84.5 118.6 111.9 251.4 79.9 19.8 60.6 141.2 108.6 143.1 875.4 68.3 358.6 177.4 78.6 473.1 853.4 158.8 110.4 61.9 340.7 63.5 125.2 53.0 72.3 105.6 114.1 300.8 273.5 114.0 298.6 96.5 3.3 2.5 581.2 1169.3 344.9 226.7 496.2 64.0 113.2 225.4 968.0 0.7 121.3 272.8 114.6 289.0 6.1 245.4 37.5 357.1 4.4 1.0 104.7 103.8 446.8 1.0 1.1 363.4 375.2 73.9 152.8 145.1 101.5 0.7 1.4 283.1 148.8 218.5 1.3 74.4 5.6 1613.0 271.1 0.7 11.3 22.4 604.8 434.2 7.8 22.6 529.0 0.9 2329.1 16.2 242.8 31.4 180.5 297.8 41.5 112.0 4.4 154.0 535.6 2.8 426.8 18.6 31.8 18.5 651.4 32.4 15.7 544.6 99.7 11.5 58.4 44.2 397.8 4.7 2.5 8.3 28.7 24.2 441.2 9.6 251.9 449.6 111.4 111.8 110.7 148.1 110.3 109.4 118.6 111.9 108.6 110.4 125.2 114.0 1157.4 721.1 359.8 33.3 42.0 631.3 624.1 1278.9 241.9 2.9 307.3 478.7 218.2 258.7 1463.3 119.5 0.0 766.1 38.8 4097.0 673.1 605.9 21.7 636.2 742.7 397.8 173.4 578.1 0.2 1057.8 1051.7 666.3 281.4 846.8 580.5 6.3 64.6 2.3 1137.4 1.7 0.5 1733.8 1778.1 287.8 844.6 44.4 555.7 651.2 848.4 14.0 639.1 300.1 9.2 2.0 0.3 1289.6 3445.9 384.0 77.4 708.4 4397.2 81.3 1506.5 14.7 144.7 220.2 521.0 11.5 6.6 524.8 797.6 483.8 119.5 2.9 1880.1 1139.7 LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 629.8;Paneth cells: 584.1;Proximal enterocytes: 931.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 862.9;SK-BR-3: 2270.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" NA NA 7100000000 "Cluster 32: T-cells - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000410: , HPA000554: AB_1079246" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.63e-3)" "unprognostic (1.62e-2)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (1.57e-2)" "unprognostic (4.55e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (1.58e-1)" "unprognostic (1.65e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" 192.8 218.6 51.2 75.0 91.4 48.6 109.5 95.6 62.3 188.8 159.8 210.8 312.9 121.4 45.2 114.2 155.6 240.8 311.4 46.6 81.4 103.1 68.5 182.8 52.7 145.6 88.3 155.6 79.1 107.8 134.9 147.0 116.8 114.3 92.6 10.0 498.7 154.2 20.0 54.0 260.9 80.2 104.3 76.8 315.6 70.1 89.8 48.8 102.0 20.4 25.3 125.0 119.0 152.5 499.0 255.3 7.2 11.2 157.3 181.4 147.9 55.7 49.0 371.3 725.7 107.5 862.9 2.8 372.7 33.5 361.7 200.1 53.6 203.7 11.5 1.2 319.0 33.8 206.0 481.0 387.7 0.4 31.6 305.8 111.5 197.5 12.6 83.8 9.9 68.7 3.4 1.5 87.7 62.8 151.2 6.0 13.0 163.7 170.7 100.1 209.9 4.8 155.5 352.6 235.1 267.4 52.7 2270.3 754.5 14.0 57.5 16.1 16.3 245.5 169.8 7.1 225.8 0.8 2.2 3.7 332.1 96.8 263.7 0.8 17.7 4.9 12.0 27.2 25.0 4.7 43.3 17.9 7.6 2.4 68.4 33.0 1.2 9.4 14.7 0.6 26.0 25.1 51.2 91.4 95.6 62.3 46.6 81.4 145.6 88.3 116.8 104.3 89.8 152.5 88.0 189.1 144.3 9.8 5.6 31.1 146.8 462.5 60.3 37.2 60.5 43.1 180.7 127.2 306.2 139.8 6.2 179.1 3.4 629.8 17.6 275.0 7.2 77.4 118.7 26.8 168.2 4.4 0.3 136.5 336.0 284.6 257.9 126.9 13.3 316.5 46.8 45.8 88.3 74.0 5.3 328.7 309.3 36.8 23.7 37.1 282.7 36.0 81.8 8.4 27.9 80.8 2.1 11.6 33.9 132.4 584.1 266.3 3.5 72.4 931.4 49.2 123.9 24.3 177.5 80.5 119.6 4.5 2.1 83.8 27.3 108.9 15.4 228.3 400.5 128.2 LGALS4 GAL4 ENSG00000171747 "Galectin 4" P56470 19 38801671-38812945 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "intestine: 1307.1" "Group enriched" "Detected in many" 4 "Distal enterocytes: 4349.4;Intestinal goblet cells: 3767.6;Paneth cells: 3353.0;Proximal enterocytes: 4572.2;Undifferentiated cells: 2684.6" "Group enriched" "Detected in many" 21 "colorectal cancer: 450.7;liver cancer: 133.6;pancreatic cancer: 213.7;stomach cancer: 190.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 205 "OE19: 987.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB025653, HPA031184, HPA031185, HPA031186" Enhanced Uncertain "Plasma membrane" NA NA 200000 "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB025653: , HPA031184: AB_2673776, HPA031185: AB_2673777, HPA031186: AB_2673778" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (2.57e-3)" "unprognostic (7.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (1.54e-1)" "unprognostic (7.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.69e-1)" "unprognostic (3.38e-1)" "unprognostic (9.71e-2)" "prognostic favorable (3.21e-4)" 1.6 0.5 0.3 86.1 0.4 0.5 5.5 0.5 0.6 1.4 0.2 1307.1 812.2 3.2 0.2 1.4 2.4 137.1 0.9 0.3 0.3 2.9 79.5 1.2 1.1 0.3 0.3 1.6 31.5 0.0 0.8 0.2 0.3 2.3 933.0 0.2 1.1 2.3 1.6 1.6 691.9 55.2 0.2 4.0 135.2 0.9 0.3 0.3 1.7 0.2 0.4 11.2 1.5 0.4 0.0 0.4 0.1 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 1.3 0.1 0.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 2.2 0.0 987.1 0.0 0.1 0.0 2.5 0.1 4.8 0.2 1.4 0.1 0.1 0.0 0.0 0.1 1.0 0.0 0.0 0.2 1.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.6 0.3 0.3 0.3 0.3 0.3 0.2 0.3 0.4 1.7 3.2 6.5 0.7 10.3 1.1 3.0 0.6 3.4 1.1 3.6 3.0 1.3 770.7 1.0 0.0 0.0 0.8 0.9 4349.4 0.0 267.1 0.2 1.9 1.8 1.2 649.7 0.0 0.3 103.3 0.5 0.8 310.4 5.7 49.0 0.8 1.8 69.0 0.1 1.7 0.3 3767.6 0.0 1.9 0.3 0.0 0.0 1.2 0.0 1.0 3.0 0.8 1.0 0.0 0.7 492.7 3353.0 0.4 0.7 1.8 4572.2 9.3 0.4 2.3 0.0 3.9 1.1 0.3 0.9 0.9 2.7 0.5 11.1 1.1 2684.6 42.4 LGALS9 LGALS9A ENSG00000168961 "Galectin 9" O00182 17 27629798-27649560 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 99.1;stomach 1: 87.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 181.1;Gastric mucus-secreting cells: 174.8;Hofbauer cells: 298.2;Intestinal goblet cells: 183.5;Kupffer cells: 254.2;Paneth cells: 181.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 40.2;HMC-1: 124.9;MOLT-4: 44.8;REH: 48.4;THP-1: 83.2;U-937: 92.1" "HPA046876, HPA047218" Approved Approved Cytosol "Secreted to blood" NA NA 448000 "Cluster 7: Monocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (2.62e-2)" "prognostic favorable (2.35e-5)" "unprognostic (1.16e-2)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (2.46e-3)" "unprognostic (1.58e-2)" "unprognostic (8.60e-2)" "unprognostic (4.79e-1)" "unprognostic (1.80e-1)" "unprognostic (8.13e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (4.76e-2)" "unprognostic (3.02e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-3)" 20.7 6.4 12.6 46.0 13.0 68.5 9.5 13.8 20.8 25.6 14.3 99.1 46.3 12.8 3.0 14.5 28.4 38.2 8.7 12.8 13.4 2.4 11.6 34.2 60.9 21.7 15.2 5.3 5.2 2.8 1.2 16.8 16.5 3.7 89.2 1.0 21.2 7.9 3.8 4.2 41.8 19.4 17.3 50.7 87.5 3.8 17.0 29.1 4.1 4.1 38.9 39.6 1.9 20.1 2.0 0.7 0.6 0.3 0.1 0.2 1.6 0.4 1.3 8.9 29.6 0.1 12.6 1.5 14.2 1.1 1.5 4.1 0.3 0.1 0.5 9.4 0.9 14.9 0.9 0.0 1.0 40.2 124.9 0.3 0.0 0.4 0.0 0.5 16.5 13.6 0.6 0.5 0.0 0.1 44.8 15.0 0.4 28.4 0.0 48.4 0.0 3.6 5.9 1.0 0.3 0.8 0.0 4.4 0.2 0.9 0.2 83.2 3.1 0.0 0.3 0.1 0.2 0.1 0.1 0.3 0.2 92.1 0.2 32.6 116.2 78.2 5.6 214.9 2.6 32.3 15.6 5.9 165.5 41.7 9.6 4.0 41.7 22.0 217.4 28.5 40.3 75.1 12.6 13.0 13.8 20.8 12.8 13.4 21.7 15.2 16.5 17.3 17.0 20.1 32.2 9.6 6.3 2.0 42.2 3.2 7.7 32.9 18.8 0.2 10.5 13.2 1.7 20.0 40.5 7.3 0.0 2.3 19.0 181.1 3.9 124.1 1.5 11.4 11.6 43.5 40.5 64.3 0.4 126.9 3.1 7.4 174.8 12.9 31.1 11.2 26.0 2.2 298.2 0.0 0.6 183.5 26.4 254.2 85.4 2.2 4.4 154.1 1.8 25.3 150.7 0.2 41.2 3.5 0.9 146.0 181.6 3.0 3.5 4.4 20.6 1.4 15.4 0.6 19.7 1.6 6.2 0.1 0.7 8.8 1.7 3.7 19.6 86.2 126.7 31.1 LLGL2 "HGL, Hugl-2" ENSG00000073350 "LLGL scribble cell polarity complex component 2" Q6P1M3 17 75525080-75575209 "Predicted intracellular proteins" "Cell cycle, Cell division, Exocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 297.5;Pancreatic endocrine cells: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.1" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;NK-cells: 2.1;T-cells: 3.1" "Cell line enhanced" "Detected in many" "CACO-2: 92.6;CAPAN-2: 134.2;MCF7: 132.1;OE19: 101.6;RT4: 92.9;SK-BR-3: 127.5;T-47d: 96.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA022913 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA022913: AB_1852930" "unprognostic (1.18e-1)" "unprognostic (4.18e-2)" "unprognostic (2.89e-2)" "unprognostic (1.34e-1)" "unprognostic (3.43e-1)" "prognostic favorable (9.25e-4)" "unprognostic (2.60e-2)" "unprognostic (2.40e-1)" "unprognostic (7.97e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.00e-5)" "unprognostic (6.22e-3)" "prognostic favorable (6.14e-9)" "unprognostic (1.14e-2)" "unprognostic (2.77e-2)" "unprognostic (4.15e-3)" "unprognostic (1.56e-2)" 3.9 7.8 2.7 14.2 6.0 4.6 9.0 6.2 3.6 16.3 9.5 64.5 54.5 4.1 24.0 55.5 14.9 21.3 3.4 2.1 4.1 56.7 26.9 27.6 5.1 6.0 5.9 4.9 74.5 17.3 11.2 6.3 6.2 14.7 28.4 10.4 43.4 12.5 1.3 34.1 55.4 1.9 4.0 24.5 64.2 6.9 4.5 2.3 17.8 0.9 5.7 9.6 25.9 9.8 60.1 54.7 0.3 10.4 0.0 0.0 22.7 0.4 0.6 1.1 0.6 92.6 134.2 4.0 13.6 0.2 5.0 73.7 10.1 10.1 0.2 5.1 18.1 4.0 16.1 35.1 0.6 0.6 8.5 0.0 13.6 0.2 2.1 1.3 2.0 5.8 7.9 5.4 0.0 132.1 3.5 7.1 7.4 101.6 21.2 6.9 0.2 14.9 28.4 92.9 22.1 4.5 11.8 127.5 4.0 12.2 96.6 9.4 0.5 0.2 0.6 0.2 1.0 6.4 9.3 1.8 0.4 0.3 2.7 0.0 0.1 0.1 3.1 0.3 0.7 0.3 0.7 2.1 0.1 0.3 0.1 1.2 0.1 2.1 0.1 1.1 0.5 0.4 2.7 6.0 6.2 3.6 2.1 4.1 6.0 5.9 6.2 4.0 4.5 9.8 7.7 89.8 51.6 3.6 9.0 10.6 34.7 17.3 12.0 15.5 28.8 20.1 3.8 74.4 40.5 90.1 166.8 3.7 44.7 297.5 31.3 84.1 0.6 88.7 7.2 9.0 95.1 0.8 1.1 138.9 8.5 3.5 158.5 87.7 22.2 7.2 4.6 25.0 6.0 8.4 0.8 113.0 32.6 3.8 6.0 1.0 4.7 4.7 3.6 5.6 5.5 28.1 50.4 0.5 49.9 249.4 159.8 4.1 16.1 37.6 84.5 47.0 53.9 117.5 6.6 1.3 6.4 1.5 18.9 27.5 21.7 4.4 21.8 7.5 136.1 89.7 LRFN4 "FIGLER6, MGC3103, SALM3." ENSG00000173621 "Leucine rich repeat and fibronectin type III domain containing 4" Q6PJG9 11 66856647-66860475 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077570 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA077570: " "unprognostic (2.25e-2)" "unprognostic (5.90e-3)" "unprognostic (7.51e-2)" "unprognostic (2.01e-2)" "unprognostic (4.35e-2)" "unprognostic (6.73e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-3)" "unprognostic (6.56e-2)" "unprognostic (6.93e-2)" "unprognostic (5.69e-2)" "unprognostic (9.45e-2)" "unprognostic (1.93e-1)" "unprognostic (6.80e-3)" "unprognostic (1.81e-1)" "unprognostic (2.85e-1)" "unprognostic (3.53e-1)" 15.3 13.4 10.8 2.2 9.2 3.9 12.7 10.6 14.1 11.5 0.0 14.8 1.5 13.4 0.1 8.0 11.6 0.7 12.3 10.6 4.5 12.0 2.6 8.4 1.6 3.8 5.2 6.3 3.0 1.2 7.9 0.9 2.3 8.8 1.3 0.5 9.2 2.3 9.6 9.4 5.9 1.0 2.1 7.7 8.3 22.9 6.0 1.2 5.8 2.0 0.6 9.2 10.7 6.3 22.5 18.9 3.0 8.7 2.3 4.5 0.2 14.5 4.7 8.7 4.7 12.0 10.8 10.6 17.1 5.4 9.6 13.2 5.2 5.0 1.0 5.2 16.7 7.8 51.3 4.6 14.6 16.5 19.8 6.6 7.8 4.0 4.0 5.3 6.4 14.4 21.0 0.4 1.3 47.2 30.5 55.0 25.0 10.2 32.4 22.0 11.8 35.0 3.8 0.1 16.6 16.0 21.1 17.5 51.1 0.6 24.0 12.7 15.1 12.1 23.0 35.0 14.0 10.2 10.1 2.3 7.6 18.2 9.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.1 10.8 9.2 10.6 14.1 10.6 4.5 3.8 5.2 2.3 2.1 6.0 6.3 4.8 0.0 1.1 10.7 1.1 2.2 2.5 7.1 0.0 18.7 3.6 5.7 0.7 0.0 2.9 3.7 4.2 0.2 1.9 15.9 0.0 1.6 17.1 7.6 18.4 4.0 1.8 1.3 9.1 0.8 1.2 4.9 4.1 10.2 1.3 9.5 2.2 0.2 5.3 13.5 9.5 12.3 6.1 3.1 2.2 29.6 3.7 4.3 5.4 1.9 7.6 2.0 3.1 5.0 6.8 4.3 9.6 1.5 1.9 5.9 0.3 0.5 2.6 8.6 0.0 3.8 6.0 5.5 2.2 2.1 1.7 0.3 2.1 11.8 16.2 1.8 LRP10 "DKFZP564C1940, LRP9, MGC8675, MST087, MSTP087" ENSG00000197324 "LDL receptor related protein 10" Q7Z4F1 14 22871740-22881713 "Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 367.2;Pancreatic endocrine cells: 314.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 59.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 59.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000932 Approved Nucleoplasm,Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Nucleoli "HPA000932: AB_2281523" "unprognostic (1.08e-1)" "unprognostic (1.52e-2)" "unprognostic (3.72e-2)" "unprognostic (4.59e-2)" "unprognostic (1.72e-1)" "unprognostic (5.01e-2)" "prognostic unfavorable (3.54e-7)" "prognostic unfavorable (9.17e-4)" "unprognostic (8.32e-2)" "unprognostic (1.48e-2)" "unprognostic (1.97e-2)" "unprognostic (4.55e-2)" "prognostic favorable (6.31e-5)" "unprognostic (3.06e-2)" "unprognostic (8.81e-2)" "unprognostic (2.27e-1)" "unprognostic (4.14e-2)" 81.8 48.7 27.3 67.4 34.1 80.3 74.9 30.6 25.4 87.1 53.5 111.1 94.8 100.3 26.5 173.4 76.0 108.7 68.1 24.1 33.2 79.2 45.1 79.9 49.7 53.8 33.0 76.8 74.6 87.7 28.8 57.0 35.2 70.0 55.9 10.4 95.2 95.1 45.7 94.6 91.3 76.1 36.9 62.5 99.8 15.5 35.1 38.9 63.3 36.0 53.8 104.7 100.0 38.8 78.9 94.3 20.4 53.4 269.9 155.4 68.6 121.6 228.6 75.1 103.4 29.1 272.4 41.2 59.5 275.8 85.9 109.8 13.3 139.2 29.5 67.5 14.3 14.4 48.4 20.5 120.0 33.0 125.4 170.8 159.4 112.7 57.9 207.3 138.8 18.7 17.9 153.8 102.8 90.3 9.3 10.0 4.4 75.8 125.6 20.8 20.6 41.5 79.1 137.8 1.8 22.1 67.3 127.5 52.4 15.2 67.1 23.5 146.3 114.9 32.5 60.4 51.1 71.6 45.6 18.7 59.6 13.2 50.2 15.3 4.7 34.6 9.7 4.7 9.5 7.3 11.9 11.3 4.6 4.9 10.1 5.8 59.1 5.4 5.5 3.8 12.4 7.3 27.3 34.1 30.6 25.4 24.1 33.2 53.8 33.0 35.2 36.9 35.1 38.8 78.4 105.8 60.9 13.1 60.5 38.5 95.8 69.1 40.9 2.3 68.0 51.7 30.4 115.8 100.4 82.8 0.0 67.9 60.7 367.2 9.8 173.3 14.1 45.5 35.3 64.2 66.5 69.7 0.2 238.5 96.5 71.8 86.6 80.6 34.9 40.2 81.4 43.2 58.7 0.0 0.2 125.4 57.0 55.0 46.8 16.5 56.8 44.1 55.2 10.3 82.2 91.4 127.7 3.5 7.3 314.0 289.6 73.0 89.8 127.3 259.8 47.6 85.8 8.8 65.7 38.8 70.4 5.4 7.9 74.6 47.5 132.4 58.2 24.6 109.1 154.1 LRRC1 "dJ523E19.1, FLJ10775, FLJ11834, LANO" ENSG00000137269 "Leucine rich repeat containing 1" Q9BTT6 6 53794497-53924125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 115.1;Late spermatids: 117.0;Oligodendrocytes: 138.8;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031603, HPA031604" Enhanced Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031603: AB_10601753, HPA031604: AB_10601224" "unprognostic (2.90e-1)" "unprognostic (8.01e-2)" "unprognostic (9.59e-3)" "unprognostic (2.46e-2)" "unprognostic (7.04e-3)" "unprognostic (1.55e-2)" "unprognostic (2.19e-3)" "unprognostic (6.37e-2)" "unprognostic (7.02e-2)" "unprognostic (7.12e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.97e-1)" "prognostic favorable (2.21e-7)" "unprognostic (1.74e-1)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-3)" 14.0 2.2 8.7 5.1 13.8 2.9 13.3 10.1 11.2 13.2 13.7 25.5 17.3 5.1 7.5 18.2 8.5 7.8 4.2 9.2 10.4 7.7 0.8 7.6 2.7 13.9 10.8 4.8 8.8 22.6 7.9 11.1 14.2 8.7 25.4 7.1 16.7 6.7 1.5 22.5 18.1 5.1 10.9 1.5 14.8 14.5 11.1 13.9 15.3 1.4 10.7 14.5 18.0 24.1 45.2 5.7 6.1 10.9 1.6 0.8 42.8 6.1 12.3 5.2 7.1 49.4 21.7 6.4 4.9 3.9 9.7 21.7 47.9 19.4 6.6 7.9 13.8 3.9 4.5 33.5 15.2 4.9 2.9 1.6 15.8 0.4 11.5 8.1 9.4 23.1 0.9 5.8 2.9 19.7 33.6 0.6 4.8 33.5 4.2 6.8 10.2 3.3 14.1 57.4 15.7 1.5 7.3 31.7 9.9 15.2 20.6 5.0 4.3 3.9 12.6 0.2 5.6 5.8 4.9 4.6 4.4 6.7 4.8 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.3 0.5 0.1 0.1 0.0 0.7 0.0 0.3 0.0 0.0 8.7 13.8 10.1 11.2 9.2 10.4 13.9 10.8 14.2 10.9 11.1 24.1 19.8 41.7 3.9 53.2 2.9 52.6 25.5 16.3 12.0 43.0 16.0 8.1 3.5 11.5 20.6 16.5 4.2 54.5 2.3 115.1 7.9 20.5 88.5 38.8 9.4 18.8 18.0 1.7 11.9 15.6 62.0 5.9 26.0 74.3 5.7 10.5 8.6 0.3 5.1 8.4 21.9 23.6 12.2 0.6 7.1 117.0 9.3 1.3 10.6 26.2 2.5 32.7 6.2 35.2 138.8 29.5 62.5 10.1 4.2 18.5 32.5 12.3 14.1 3.0 6.6 3.5 3.7 27.3 7.3 19.9 52.7 107.4 3.1 1.6 24.5 32.5 LRRC19 FLJ21302 ENSG00000184434 "Leucine rich repeat containing 19" Q9H756 9 26993136-27005672 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 36.2;kidney: 42.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 152.3;Paneth cells: 36.0;Proximal enterocytes: 82.1;Proximal tubular cells: 57.0;Undifferentiated cells: 36.0" "Group enriched" "Detected in some" 5 "colorectal cancer: 6.0;renal cancer: 5.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA 190000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.27e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (6.30e-2)" "unprognostic (5.20e-2)" "unprognostic (2.30e-1)" "unprognostic (4.05e-2)" "unprognostic (1.85e-2)" "unprognostic (4.16e-2)" "unprognostic (9.21e-5)" "unprognostic (1.87e-2)" "unprognostic (4.48e-2)" "prognostic favorable (7.08e-8)" "unprognostic (2.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" 0.0 0.1 0.1 2.7 0.1 0.3 0.0 0.4 0.1 0.0 1.0 36.2 23.4 0.1 0.0 0.0 0.0 5.9 0.0 0.1 0.1 42.8 1.4 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 32.6 0.2 0.0 0.1 0.2 0.2 31.4 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.3 0.0 0.2 0.0 0.0 0.1 0.9 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.2 0.3 0.1 0.0 0.2 0.4 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 18.6 0.0 23.9 0.0 0.0 0.1 152.3 9.8 0.1 0.1 0.4 0.4 0.2 6.0 0.0 0.7 0.4 0.0 0.1 0.0 0.3 0.0 0.1 0.0 3.7 0.0 0.0 0.7 20.3 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.1 36.0 0.4 0.0 0.0 82.1 57.0 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.2 36.0 0.0 LRRC45 MGC20806 ENSG00000169683 "Leucine rich repeat containing 45" Q96CN5 17 82023305-82031151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023372, HPA023382, HPA024768" Enhanced Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centrosome, Cytosol" "Nucleoplasm, Plasma membrane" "HPA023372: AB_1853317, HPA023382: AB_1853318, HPA024768: AB_10602348" "unprognostic (6.69e-2)" "unprognostic (6.10e-2)" "unprognostic (6.86e-2)" "unprognostic (1.38e-2)" "unprognostic (6.92e-2)" "unprognostic (4.41e-3)" "unprognostic (4.70e-3)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (1.78e-3)" "unprognostic (6.17e-3)" "unprognostic (7.46e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (4.79e-2)" "unprognostic (3.58e-1)" 5.0 6.1 2.3 3.8 2.2 7.0 5.8 7.5 5.4 6.1 2.2 8.7 5.7 5.4 0.9 10.3 9.0 1.6 5.0 2.5 1.9 7.5 18.0 6.4 3.2 3.0 2.8 4.5 10.1 2.0 5.9 2.4 3.0 8.4 1.7 0.6 9.6 2.2 2.5 8.7 8.6 1.2 2.1 9.5 10.5 4.0 2.2 3.1 8.9 0.5 1.5 6.1 6.9 2.3 18.6 20.7 6.2 12.7 2.5 3.3 24.0 12.7 5.2 7.5 6.3 18.6 12.4 13.9 11.2 2.5 7.8 21.3 6.0 7.6 1.7 8.5 38.6 8.8 43.1 25.5 2.1 10.4 21.2 3.3 3.1 4.5 1.2 3.1 11.1 13.0 6.3 6.0 2.0 31.6 23.5 34.5 6.4 15.0 27.4 19.0 12.2 7.8 4.8 16.9 19.1 18.6 5.8 29.9 11.2 3.0 24.4 12.0 6.5 13.1 16.3 20.8 21.9 11.5 3.1 2.1 7.0 8.9 13.9 2.3 1.2 1.5 1.4 0.9 1.4 0.6 1.6 1.6 0.8 0.7 0.8 1.1 0.0 1.1 0.4 1.3 1.4 1.4 2.3 2.2 7.5 5.4 2.5 1.9 3.0 2.8 3.0 2.1 2.2 2.3 3.9 6.4 2.2 4.2 4.1 4.5 5.0 2.9 1.8 5.2 8.5 8.6 2.7 14.3 7.0 3.7 0.0 12.7 7.8 18.1 5.9 7.3 1.5 19.0 3.4 3.7 4.8 10.3 2.5 4.7 27.9 4.8 13.3 5.0 4.5 13.3 7.1 12.6 8.7 5.0 2.9 12.2 4.1 6.3 3.2 4.4 7.2 4.2 8.8 0.0 4.3 5.6 7.2 1.0 1.8 5.8 9.4 6.4 8.5 2.4 10.9 10.2 24.4 4.1 0.0 2.8 5.2 2.3 11.9 6.3 2.4 3.0 7.0 4.9 18.4 3.7 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503637-41513887 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.2;lung: 15.1;salivary gland: 11.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 25.3;Gastric mucus-secreting cells: 18.8;Hepatic stellate cells: 11.4;Intestinal goblet cells: 7.9;Proximal enterocytes: 15.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MAIT T-cell: 5.7;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 10 "dendritic cells: 5.0;T-cells: 5.7" "Cell line enhanced" "Detected in some" "HEL: 5.0;NB-4: 9.7;RH-30: 4.6;THP-1: 14.7" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA059545: AB_2684057" "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 0.8 0.6 1.0 1.4 1.6 4.6 0.5 1.2 1.8 0.9 0.6 5.2 12.5 0.2 0.0 0.3 0.4 2.4 1.7 1.3 0.7 4.0 2.9 15.1 1.2 0.6 0.6 0.1 0.3 0.6 0.7 10.4 0.7 0.4 5.7 0.1 11.8 0.3 1.8 1.4 13.2 0.3 0.6 5.5 9.9 2.5 0.8 0.4 0.7 0.0 2.1 0.7 0.7 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.6 0.8 1.2 2.2 0.0 0.0 0.0 0.6 0.0 0.0 2.6 0.0 0.4 0.2 1.3 5.0 0.1 0.0 2.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 1.9 0.0 1.8 0.0 0.0 9.7 0.4 1.8 0.2 0.2 4.6 0.1 0.0 0.0 0.4 2.9 0.1 0.2 0.0 2.6 0.2 14.7 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.8 0.0 0.0 0.0 0.4 0.0 5.7 0.5 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 1.0 1.6 1.2 1.8 1.3 0.7 0.6 0.6 0.7 0.6 0.8 0.9 0.3 0.0 0.0 0.3 1.6 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.8 2.8 0.9 0.0 0.0 0.3 5.5 25.3 0.0 0.0 2.8 0.1 0.4 1.8 1.8 3.2 2.9 0.2 1.5 0.2 18.8 0.2 0.0 0.3 11.4 0.5 0.1 0.0 0.2 7.9 0.0 1.9 0.6 2.1 0.0 0.4 3.6 0.0 0.4 0.0 1.0 0.5 0.4 0.7 5.5 0.0 2.7 0.0 15.3 0.0 5.6 0.0 0.0 0.3 0.5 2.2 1.2 0.0 0.1 0.4 4.0 0.0 3.8 0.0 LYPD8 ENSG00000259823 "LY6/PLAUR domain containing 8" Q6UX82 1 248739415-248755759 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 215.9" "Group enriched" "Detected in some" 5 "Distal enterocytes: 710.5;Paneth cells: 1098.0" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 15.2" "Group enriched" "Detected in many" 10 "amygdala: 1.1;basal ganglia: 1.6;cerebral cortex: 1.9;hippocampal formation: 1.1;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.69e-3)" "unprognostic (3.53e-2)" "unprognostic (1.08e-5)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-4)" "unprognostic (8.62e-2)" "unprognostic (7.28e-2)" "unprognostic (3.22e-1)" "unprognostic (9.73e-2)" "unprognostic (1.87e-1)" "unprognostic (1.19e-4)" "unprognostic (2.57e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" 0.1 0.0 1.1 11.4 1.6 0.5 0.6 0.0 1.9 0.0 0.0 215.9 0.7 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 126.8 0.0 0.0 0.4 0.0 0.0 26.4 3.5 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 1.1 1.6 0.0 1.9 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 710.5 1.9 0.0 4.7 0.0 0.0 0.0 31.5 0.0 15.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 166.9 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 1098.0 0.0 0.0 0.1 38.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.3 0.3 0.0 16.6 0.0 LYPLA2 APT-2 ENSG00000011009 "Lysophospholipase 2" O95372 1 23791145-23795539 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063151 Uncertain Nucleoplasm,Cytosol NA NA 110000 "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA063151: " "unprognostic (8.84e-2)" "unprognostic (6.87e-2)" "unprognostic (2.65e-1)" "unprognostic (7.81e-3)" "unprognostic (2.12e-2)" "unprognostic (2.22e-2)" "prognostic unfavorable (5.84e-5)" "unprognostic (3.06e-1)" "unprognostic (1.80e-1)" "unprognostic (5.18e-2)" "unprognostic (2.52e-1)" "unprognostic (2.40e-1)" "prognostic favorable (4.99e-4)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-3)" "unprognostic (1.24e-1)" 32.6 41.1 31.3 33.3 33.2 55.2 33.4 31.1 43.9 33.1 82.4 48.9 49.6 28.2 13.7 76.2 43.2 32.3 40.9 40.4 31.3 79.5 82.2 40.8 43.5 31.1 32.3 28.4 43.7 77.2 35.0 37.1 30.2 45.2 29.4 15.7 51.2 24.7 43.4 51.3 51.3 20.1 30.6 61.1 47.7 23.4 33.0 42.8 39.0 25.2 33.2 46.3 40.3 28.2 80.3 54.2 61.0 70.6 30.4 37.0 83.7 50.8 49.4 50.0 42.6 75.2 130.1 45.8 67.7 49.4 34.9 78.2 45.7 141.2 19.8 88.4 67.9 58.1 87.1 127.5 49.8 54.0 72.5 48.1 85.3 74.9 27.5 61.9 118.8 52.6 84.2 45.4 55.0 89.4 67.3 90.0 120.3 72.6 76.6 78.9 35.0 79.1 122.6 64.6 87.2 149.4 57.7 87.0 88.5 43.5 71.7 58.6 98.6 46.5 61.2 56.7 43.2 116.4 104.1 62.6 74.3 125.1 58.5 82.7 95.3 125.0 105.8 96.0 87.1 62.9 89.1 93.9 77.9 67.9 75.6 80.0 113.2 83.5 80.2 58.8 88.7 113.6 31.3 33.2 31.1 43.9 40.4 31.3 31.1 32.3 30.2 30.6 33.0 28.2 21.3 9.6 27.3 6.2 27.7 38.9 31.0 80.0 23.3 34.1 36.9 35.4 16.1 35.8 36.5 36.8 18.8 118.7 29.9 105.0 68.4 105.8 15.5 44.9 13.7 33.8 44.3 26.9 5.1 112.8 108.8 19.1 40.8 27.5 36.8 23.1 21.0 35.0 69.3 23.5 5.7 53.5 52.9 17.2 23.3 13.4 10.5 27.6 19.6 4.7 62.1 30.2 46.4 7.5 5.2 130.2 71.9 6.4 20.8 33.3 77.1 92.2 57.6 26.0 26.3 8.6 23.3 8.0 19.1 33.1 41.5 115.9 36.2 64.0 56.6 42.4 MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 368.5;intestine: 235.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 857.8;Ductal cells: 299.2;Pancreatic endocrine cells: 354.9;Paneth cells: 374.4;Proximal enterocytes: 742.2;Urothelial cells: 426.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.4;neutrophil: 2.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "A-431: 267.4;A549: 269.9;CAPAN-2: 347.7;fHDF/TERT166: 380.9;HaCaT: 276.4;PC-3: 158.3" "Not detected" "Not detected" HPA051410 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" 17.2 2.9 3.9 17.2 3.7 2.4 13.4 3.6 3.8 58.2 4.7 114.1 235.4 6.3 5.7 368.5 8.4 20.3 18.6 3.6 4.9 7.0 3.1 79.9 6.1 4.1 4.2 2.0 4.4 97.8 2.6 9.3 4.6 18.9 95.1 0.4 40.8 4.2 6.3 43.7 218.8 14.4 4.9 5.0 9.2 9.7 6.9 3.1 28.6 10.8 55.0 98.6 148.1 4.2 267.4 269.9 0.2 0.9 0.1 0.1 0.8 48.5 2.1 0.2 0.2 44.3 347.7 0.6 127.6 380.9 0.1 276.4 0.0 12.6 0.1 0.7 0.2 1.8 7.3 0.1 1.9 0.1 0.6 4.8 13.9 1.2 0.0 0.0 111.9 0.0 0.1 0.4 0.0 10.0 0.0 1.0 0.2 117.8 158.3 0.1 0.1 1.2 30.4 15.3 0.7 0.2 0.2 9.3 0.7 0.4 0.3 1.4 130.9 0.4 0.9 0.7 0.8 0.3 0.4 31.7 0.4 0.4 0.2 8.4 0.4 0.6 0.2 0.2 0.2 0.5 0.5 0.4 0.2 0.5 0.3 0.5 2.5 1.2 0.1 0.4 0.3 0.3 3.9 3.7 3.6 3.8 3.6 4.9 4.1 4.2 4.6 4.9 6.9 4.2 45.1 41.7 185.9 0.3 2.0 16.4 107.2 38.6 3.4 0.0 10.9 6.1 3.2 2.8 64.6 1.8 0.0 0.3 0.4 857.8 0.0 299.2 26.3 3.2 1.8 50.6 17.5 0.0 0.8 66.1 0.1 8.2 2.6 7.6 7.0 0.4 33.9 0.5 8.2 0.0 0.1 51.2 30.5 0.9 3.8 9.7 2.5 2.9 14.2 2.8 1.0 0.1 0.0 0.0 0.0 354.9 374.4 1.2 0.0 187.4 742.2 14.6 19.4 0.1 0.0 1.1 5.6 27.2 1.3 57.9 13.2 0.5 2.4 0.6 97.4 426.0 MAMDC4 "AEGP, DKFZp434M1411, EDTB" ENSG00000177943 "MAM domain containing 4" Q6UXC1 9 136850943-136860799 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 30.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 22.9;Hepatocytes: 26.6;Horizontal cells: 16.8;Intestinal goblet cells: 21.8;Proximal enterocytes: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 16.9" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Low region specificity" "Detected in all" "CAB026377, HPA059977" Approved Nucleoplasm,Cytosol NA Yes "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB026377: , HPA059977: AB_2684186" "unprognostic (2.79e-1)" "unprognostic (7.90e-2)" "unprognostic (4.09e-3)" "unprognostic (6.86e-2)" "unprognostic (8.33e-2)" "unprognostic (2.66e-4)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (7.37e-2)" "prognostic favorable (1.88e-6)" "unprognostic (8.22e-3)" "unprognostic (1.58e-2)" "unprognostic (1.22e-3)" "unprognostic (9.22e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" 2.7 3.2 1.6 1.6 2.0 1.4 2.4 7.2 3.1 3.9 1.5 7.3 3.9 2.5 0.3 2.8 4.5 0.7 6.1 1.4 1.3 8.3 30.7 3.6 0.9 2.1 1.9 3.1 7.4 0.6 15.0 1.0 2.2 7.7 0.8 0.7 3.3 1.0 2.5 2.0 5.8 0.5 1.1 9.7 3.9 4.3 1.7 0.6 11.4 0.9 0.2 2.6 3.1 3.3 1.5 2.5 1.3 2.6 0.5 0.1 16.9 2.5 0.3 0.3 0.5 1.9 1.4 1.3 0.6 0.6 0.7 2.1 0.3 1.2 0.0 1.9 0.9 0.8 6.1 2.2 1.0 0.1 4.6 0.8 1.5 1.2 0.5 1.3 0.7 2.3 2.6 1.1 0.2 4.0 0.9 3.5 1.3 1.0 0.7 1.5 0.4 2.3 0.8 1.3 1.5 1.9 0.5 1.2 1.1 0.8 4.0 0.8 0.7 6.8 4.2 1.4 0.4 2.8 1.6 0.4 1.5 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.0 7.2 3.1 1.4 1.3 2.1 1.9 2.2 1.1 1.7 3.3 1.0 0.0 3.4 6.8 2.0 0.8 1.0 3.9 1.2 5.9 2.4 3.6 7.9 11.5 1.8 1.8 0.0 2.5 2.6 22.9 1.9 0.8 2.2 0.6 1.1 1.5 0.0 3.2 1.1 4.8 3.9 2.4 4.1 1.4 0.0 6.7 2.5 26.6 2.6 16.8 2.1 21.8 6.1 1.9 1.2 2.7 1.8 1.6 0.0 0.0 1.7 2.9 1.0 2.5 1.9 0.9 11.3 1.5 3.0 1.4 23.4 2.5 2.9 7.6 0.0 1.0 2.4 1.6 2.1 0.9 0.4 2.3 1.8 1.8 12.4 0.6 MAP1LC3B2 ATG8G ENSG00000258102 "Microtubule associated protein 1 light chain 3 beta 2" A6NCE7 12 116548105-116576606 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.5;Langerhans cells: 33.4;Paneth cells: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 7.2" "HPA042824, HPA052474, HPA052484, HPA053767" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Nucleoplasm "HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846, HPA053767: AB_2682253" "unprognostic (1.50e-1)" "unprognostic (6.94e-2)" "unprognostic (9.14e-2)" "unprognostic (3.89e-3)" "unprognostic (1.62e-1)" "unprognostic (1.22e-1)" "unprognostic (2.43e-3)" "unprognostic (3.15e-1)" "unprognostic (2.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (1.11e-3)" "unprognostic (6.66e-3)" "unprognostic (1.65e-1)" "unprognostic (1.53e-2)" "unprognostic (3.42e-1)" 1.8 2.2 0.3 0.7 0.4 3.9 1.5 2.0 0.6 0.7 0.8 0.9 1.2 1.3 1.2 1.8 1.0 1.6 2.4 0.3 0.8 1.3 1.1 1.2 1.1 0.5 0.6 1.4 0.8 0.1 0.9 0.7 0.7 0.8 1.5 0.9 1.2 0.0 4.2 1.6 1.4 1.5 0.5 0.8 0.8 1.1 0.4 0.7 0.9 0.5 1.5 0.8 0.9 0.7 1.4 0.7 1.5 1.8 0.4 0.5 1.6 2.8 0.2 0.0 0.1 2.7 2.0 1.1 1.8 0.2 3.4 1.0 0.4 0.3 0.5 1.0 1.9 0.6 2.7 4.9 0.9 0.9 1.0 0.1 0.4 0.9 0.7 3.9 1.9 1.2 3.3 3.0 0.3 2.7 1.0 1.9 0.8 1.2 2.6 1.4 0.2 3.6 0.2 1.5 1.5 2.3 1.9 0.6 7.2 2.8 1.0 0.4 0.7 2.6 0.9 2.2 1.4 2.2 3.3 3.6 3.9 1.4 1.3 38.6 11.6 34.2 7.8 11.8 7.2 9.0 8.8 7.9 9.4 7.7 6.1 7.0 43.5 9.8 14.2 9.6 15.9 13.6 0.3 0.4 2.0 0.6 0.3 0.8 0.5 0.6 0.7 0.5 0.4 0.7 1.9 0.0 1.7 10.7 4.0 24.2 17.3 6.1 0.0 1.5 1.1 2.5 40.5 1.5 4.6 0.0 0.0 2.5 2.8 22.7 7.9 0.2 12.3 2.8 2.2 8.0 1.8 24.0 4.4 0.0 2.4 8.3 0.0 5.9 7.0 0.9 2.5 2.0 4.5 13.5 8.6 7.5 12.2 7.2 33.4 14.2 4.7 5.5 10.6 1.0 2.4 0.5 7.2 4.0 1.7 0.4 63.1 3.8 0.1 12.5 2.5 8.1 3.1 1.1 0.0 9.0 8.0 20.8 11.5 0.0 21.5 11.4 8.2 0.8 5.9 21.8 MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597756-65615382 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010165 Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite, Cytosol" "CAB010165: AB_631936" "unprognostic (8.36e-2)" "unprognostic (1.17e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-2)" "unprognostic (4.50e-2)" "unprognostic (4.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.77e-2)" "unprognostic (3.13e-2)" "unprognostic (2.01e-2)" "unprognostic (7.62e-2)" "unprognostic (1.95e-1)" "unprognostic (8.27e-3)" 47.6 32.6 39.9 36.9 51.7 24.4 42.9 45.1 48.4 27.2 27.2 40.0 48.3 29.7 7.4 35.6 31.3 13.5 53.2 36.1 38.8 48.5 95.3 62.7 23.7 48.8 50.3 21.0 35.8 12.1 27.8 21.6 44.6 39.2 11.7 2.8 29.1 12.6 20.1 35.9 51.0 10.0 41.5 78.3 36.3 21.3 50.5 19.3 37.3 10.4 11.3 29.2 28.3 60.1 48.0 43.4 23.1 22.6 7.0 8.0 21.7 19.3 11.9 19.9 14.9 43.4 43.9 16.4 65.5 13.0 33.0 40.9 12.2 19.5 7.1 40.2 15.5 50.0 28.2 50.9 18.6 28.9 71.2 12.4 19.1 14.5 13.3 21.6 57.4 21.5 21.6 32.7 10.9 58.2 34.0 50.9 24.2 31.0 48.1 56.1 13.3 36.2 19.2 43.1 19.6 22.9 22.0 58.1 107.7 10.4 46.6 45.8 68.8 31.3 35.8 48.1 32.4 23.3 27.5 15.8 35.3 33.1 75.1 7.5 10.5 13.1 3.1 15.3 3.0 2.7 3.2 4.5 10.1 3.0 2.4 1.8 17.3 2.4 15.4 3.0 1.8 9.5 39.9 51.7 45.1 48.4 36.1 38.8 48.8 50.3 44.6 41.5 50.5 60.1 70.0 22.4 21.1 4.2 22.1 21.0 25.3 18.4 20.5 24.4 28.9 23.4 8.7 31.5 14.1 11.0 25.0 24.7 26.4 123.5 19.6 21.9 13.5 15.4 11.3 78.9 41.9 13.0 4.1 27.5 17.7 11.4 44.4 26.1 26.0 19.6 58.5 56.2 53.3 18.5 3.5 54.9 20.3 50.6 65.5 68.5 9.6 48.3 21.4 21.5 50.2 16.1 23.7 3.0 29.5 33.7 99.0 6.4 15.5 28.1 113.1 27.6 10.3 54.7 32.9 10.5 12.8 12.2 18.3 24.8 30.0 34.3 24.0 28.9 55.2 34.6 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 336.9;Early spermatids: 267.2;Proximal enterocytes: 235.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 49.1;neutrophil: 21.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 49.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported Nucleoplasm NA NA 46000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 99.5 64.3 178.7 42.4 162.3 45.2 86.3 113.0 200.9 93.3 86.0 117.2 103.1 74.9 27.4 129.6 71.6 65.3 65.4 168.6 132.7 49.4 21.2 71.3 37.8 135.6 148.7 78.7 33.7 61.2 55.8 70.2 142.3 49.2 91.9 71.5 61.0 43.3 51.7 77.6 113.2 58.7 127.4 57.4 86.4 31.6 129.5 31.4 58.0 57.0 49.3 64.8 89.0 130.9 56.3 30.0 62.2 35.7 153.7 202.4 35.1 40.7 101.1 63.4 75.3 36.4 110.0 56.3 39.7 115.5 73.2 20.6 53.3 47.8 61.0 106.9 61.8 17.3 31.6 61.8 154.2 13.0 46.2 125.8 27.3 72.5 32.2 96.1 163.7 60.3 24.3 70.0 85.2 147.1 59.2 21.5 16.9 113.6 26.1 68.9 37.3 127.4 58.0 35.0 55.2 39.3 23.2 81.8 24.1 50.5 53.5 30.7 117.2 41.7 35.4 48.4 14.5 79.1 39.3 29.6 83.3 27.1 30.0 6.2 5.1 49.1 1.6 3.7 2.6 2.3 3.7 3.0 2.8 2.5 2.6 2.9 21.5 2.2 2.0 2.8 6.6 2.8 178.7 162.3 113.0 200.9 168.6 132.7 135.6 148.7 142.3 127.4 129.5 130.9 95.5 22.4 17.5 7.5 10.7 9.8 22.2 11.4 5.7 30.4 23.3 19.9 15.4 20.0 13.0 9.2 22.9 77.6 15.2 336.9 23.5 39.8 267.2 24.8 25.1 68.1 54.7 6.1 7.7 61.2 134.2 34.7 79.0 15.7 2.5 19.1 71.7 7.0 45.2 8.4 10.3 159.3 22.4 26.4 12.3 176.0 32.3 20.6 23.2 7.5 24.5 67.0 13.4 7.1 9.8 118.8 167.2 27.4 6.2 13.5 235.6 23.9 24.7 41.5 19.7 18.8 29.3 10.9 19.8 15.8 13.2 33.8 14.5 40.0 94.9 22.4 MAPKAPK5 "MK5, PRAK" ENSG00000089022 "MAPK activated protein kinase 5" Q8IW41 12 111842228-111902222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" 18.1 20.8 12.6 17.9 14.4 27.1 20.4 14.9 15.0 15.2 15.7 28.2 25.5 15.7 20.7 17.2 16.1 12.2 16.7 15.3 14.3 20.3 19.4 17.5 20.7 12.3 12.4 18.1 20.4 21.4 11.6 20.3 11.8 17.0 30.7 27.2 17.4 15.6 30.4 20.1 28.2 18.9 11.3 15.6 18.0 15.9 12.9 23.2 19.3 25.3 19.3 18.5 14.4 13.8 32.4 42.1 40.0 33.7 28.2 28.4 60.6 31.7 38.1 47.7 32.7 54.8 25.9 48.6 22.9 37.7 28.4 31.6 53.1 33.2 44.4 32.6 29.0 43.4 29.5 44.2 34.1 55.1 29.4 30.2 46.7 45.6 53.7 36.0 35.6 43.4 61.0 18.7 35.3 36.4 55.2 86.6 56.9 79.1 29.4 53.7 29.1 46.9 37.9 46.2 49.0 41.4 36.1 60.5 46.3 36.2 49.1 62.0 31.2 26.8 27.2 27.9 40.4 37.8 50.1 57.4 32.7 39.4 38.9 1.1 3.3 2.3 4.2 2.4 2.2 3.5 2.7 3.0 2.2 3.1 4.2 3.1 1.6 2.9 8.8 2.6 4.8 1.8 12.6 14.4 14.9 15.0 15.3 14.3 12.3 12.4 11.8 11.3 12.9 13.8 16.9 3.2 23.1 12.1 22.3 20.5 22.3 12.5 21.1 47.0 18.3 14.0 20.1 22.8 15.4 3.7 41.7 29.9 32.4 34.1 13.7 28.2 17.2 14.2 17.3 16.0 36.6 15.8 24.6 29.6 33.3 19.4 20.9 15.2 2.5 22.3 14.6 13.4 19.9 23.5 22.3 47.3 14.2 21.2 17.7 7.3 15.5 15.0 8.8 14.0 27.8 19.6 25.7 15.6 21.8 36.3 27.4 17.7 21.6 37.5 63.6 21.8 12.0 36.4 19.7 22.6 19.8 30.7 40.3 23.6 21.3 30.1 22.2 22.5 32.3 32.3 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 11.3 13.8 12.6 21.1 16.1 24.0 16.8 8.1 16.3 18.5 10.8 25.9 26.1 14.6 7.7 51.8 16.6 14.1 20.9 14.9 9.3 13.9 13.1 17.0 21.5 11.8 9.3 12.0 22.4 19.4 19.8 14.9 11.5 20.5 22.4 8.8 27.0 13.1 20.8 40.9 25.1 16.3 7.3 24.1 20.9 10.6 9.5 23.2 19.5 13.7 24.0 19.3 25.0 17.9 52.0 34.1 26.6 28.6 14.6 18.6 35.2 20.8 20.0 29.5 22.3 34.1 49.5 37.8 35.6 20.8 32.0 57.5 26.9 28.7 24.6 26.7 20.9 40.7 23.9 20.3 17.0 45.9 51.4 10.9 36.8 27.0 21.4 13.5 24.7 33.6 35.7 36.5 19.5 64.4 49.3 29.9 31.7 36.0 24.2 39.9 20.4 39.7 19.1 39.8 37.9 25.4 34.7 90.2 24.3 28.9 65.1 26.4 22.7 30.3 19.1 39.6 23.4 24.5 28.8 36.7 20.1 23.2 25.3 1.4 0.7 2.1 1.3 0.7 2.1 0.9 1.0 1.3 1.0 1.6 0.8 0.9 3.6 1.6 1.1 0.9 0.6 0.7 12.6 16.1 8.1 16.3 14.9 9.3 11.8 9.3 11.5 7.3 9.5 17.9 17.3 6.4 6.8 29.7 18.5 25.2 21.1 9.1 19.4 26.8 30.0 18.2 12.8 27.1 11.9 20.2 8.4 26.0 33.4 90.3 1.9 20.2 0.6 29.5 15.8 14.7 29.9 14.7 43.6 21.4 20.6 11.7 27.0 41.0 17.2 21.1 13.6 13.0 17.9 20.2 30.3 39.9 10.2 26.7 18.5 0.9 12.8 25.0 3.6 29.0 17.0 18.8 36.0 31.7 51.8 27.3 39.4 10.9 15.6 30.4 33.4 8.1 14.5 18.1 19.7 19.6 13.1 9.1 18.4 39.9 34.4 65.0 23.6 16.0 33.6 44.3 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036122 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 170.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.9;Inhibitory neurons: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 18.3 11.8 16.2 11.0 15.5 8.0 18.7 15.4 17.5 57.4 7.3 39.1 21.9 43.5 12.8 14.7 31.2 19.0 65.3 15.2 19.4 12.2 18.9 17.8 8.9 19.7 27.7 51.9 9.2 13.9 27.0 8.6 26.4 40.0 25.3 24.0 18.4 15.4 170.6 14.6 30.7 26.3 14.6 7.2 24.0 56.3 18.3 5.8 13.2 73.1 11.1 46.9 28.8 15.7 31.7 25.1 24.7 19.2 30.7 41.4 27.6 32.2 22.8 29.4 32.6 29.4 10.1 48.8 15.2 38.6 59.9 15.7 30.1 18.8 30.4 23.7 16.4 22.2 29.2 27.4 28.4 12.0 27.3 34.1 23.7 49.8 37.0 35.2 27.5 12.5 17.3 14.6 34.2 21.9 17.7 12.5 20.4 21.2 28.2 25.6 40.7 9.4 16.1 16.8 34.0 20.6 38.0 50.4 16.3 26.9 22.8 11.9 27.9 55.7 36.8 30.1 33.0 19.5 18.9 17.5 38.0 16.0 24.2 0.0 0.3 0.4 0.3 0.2 0.4 0.0 0.2 0.4 0.6 0.1 0.1 0.2 0.0 0.5 1.5 0.0 0.0 0.2 16.2 15.5 15.4 17.5 15.2 19.4 19.7 27.7 26.4 14.6 18.3 15.7 5.5 0.0 2.0 32.0 2.3 4.2 4.1 3.0 8.0 15.8 8.2 6.7 46.5 4.3 5.5 3.7 54.2 6.1 2.4 66.9 1.9 4.6 38.0 4.4 17.0 7.3 12.1 6.5 45.4 6.3 4.8 12.0 12.8 7.8 0.0 13.0 3.6 6.6 6.2 5.0 86.6 24.6 0.0 2.8 7.8 57.7 9.0 5.3 7.2 30.9 2.5 3.7 7.2 52.3 52.5 8.3 33.9 10.1 5.5 10.7 50.2 5.7 3.1 12.8 6.6 11.7 9.0 28.0 13.2 6.3 2.7 5.5 3.5 12.4 22.4 7.4 MAVS "Cardif, IPS-1, KIAA1271, VISA" ENSG00000088888 "Mitochondrial antiviral signaling protein" Q7Z434 20 3846799-3876123 "Predicted membrane proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009187, HPA049850, HPA053524" Enhanced Enhanced Mitochondria NA NA 600000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009187: , HPA049850: AB_2680912, HPA053524: AB_2682177" "unprognostic (1.30e-2)" "unprognostic (4.51e-2)" "unprognostic (2.17e-1)" "unprognostic (6.67e-2)" "unprognostic (1.42e-1)" "unprognostic (1.75e-1)" "unprognostic (1.18e-3)" "unprognostic (2.23e-2)" "unprognostic (2.30e-2)" "unprognostic (5.95e-2)" "prognostic favorable (3.81e-4)" "unprognostic (1.92e-1)" "prognostic favorable (4.13e-5)" "unprognostic (4.97e-2)" "unprognostic (3.03e-1)" "unprognostic (3.12e-2)" "unprognostic (7.39e-2)" 14.2 12.5 13.0 11.5 16.0 10.3 13.0 13.9 13.6 11.6 14.1 19.4 14.8 12.0 8.4 14.9 13.2 6.7 21.3 12.1 11.5 15.8 15.5 13.3 9.9 18.6 15.7 16.8 17.6 15.4 12.1 9.4 15.9 14.2 15.4 8.1 13.0 10.3 37.5 18.9 16.9 9.6 14.0 14.3 15.4 4.9 16.1 10.4 14.0 29.2 10.8 14.3 11.0 16.6 31.6 36.0 14.3 17.9 38.8 26.2 11.2 18.7 23.8 19.5 14.2 28.4 19.9 13.6 11.1 26.4 55.6 38.7 17.3 28.0 19.9 8.4 8.4 26.3 14.6 45.5 21.4 16.6 10.6 26.7 23.4 33.2 19.6 19.4 20.1 17.6 30.2 10.1 19.3 28.5 25.3 14.1 9.2 15.7 19.6 18.8 19.9 13.7 20.8 31.2 10.7 11.2 21.3 41.0 18.1 20.3 21.9 15.3 30.5 26.5 9.7 31.7 22.1 20.7 26.6 9.4 10.5 20.1 13.7 1.7 2.1 2.0 1.4 1.6 1.0 1.1 1.1 1.1 1.4 1.3 1.2 1.2 1.9 1.8 1.9 1.7 0.9 1.6 13.0 16.0 13.9 13.6 12.1 11.5 18.6 15.7 15.9 14.0 16.1 16.6 16.6 57.7 48.5 24.8 17.3 2.2 13.9 3.7 19.4 34.0 19.9 13.2 61.0 58.6 21.7 29.5 16.7 33.6 22.5 100.0 13.7 25.9 1.1 16.1 27.5 26.8 34.7 17.1 13.6 30.5 27.5 22.8 25.0 16.6 8.8 36.5 44.3 45.7 25.5 45.4 15.9 32.6 2.0 37.7 2.9 3.2 30.7 20.7 1.8 15.9 32.4 20.7 20.6 12.5 19.9 32.7 29.5 28.2 14.2 18.1 42.8 19.6 16.2 33.7 32.9 26.2 17.5 6.2 4.1 15.6 2.0 18.1 16.7 27.5 57.9 16.6 MAZ "Pur-1, ZF87, Zif87, ZNF801" ENSG00000103495 "MYC associated zinc finger protein" P56270 16 29806106-29811164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048315, HPA059495, HPA065930" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA048315: AB_2680353, HPA059495: AB_2684039, HPA065930: AB_2685579" "unprognostic (1.05e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (3.83e-1)" "unprognostic (3.25e-3)" "unprognostic (6.16e-2)" "unprognostic (1.27e-1)" "unprognostic (5.12e-2)" "unprognostic (2.00e-1)" "unprognostic (6.39e-3)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.20e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (7.08e-2)" 71.0 91.7 156.7 92.1 153.0 270.3 65.5 147.4 179.9 87.4 125.2 139.4 92.7 90.1 51.4 92.6 88.6 73.6 74.4 158.9 134.8 63.6 101.2 73.2 123.9 140.4 144.6 96.7 105.4 113.3 83.0 61.8 136.6 122.9 101.0 50.8 86.2 75.4 126.2 96.3 87.7 75.8 134.8 97.8 85.5 89.9 143.9 256.0 79.5 93.1 111.2 94.4 68.4 145.2 227.2 294.8 298.8 326.9 158.4 149.6 268.4 161.0 130.6 246.0 177.4 378.5 316.5 402.4 205.2 316.9 121.6 201.3 494.2 210.9 87.5 329.9 792.4 267.7 641.3 526.2 222.1 668.7 318.8 160.7 292.1 207.2 232.5 228.7 249.4 556.7 398.5 343.3 118.3 927.1 644.8 566.3 303.7 246.1 227.6 627.9 281.3 468.5 202.3 242.2 456.1 355.1 153.8 330.1 204.6 190.5 284.3 633.7 172.8 269.8 215.4 103.6 256.1 249.3 344.4 448.5 131.9 435.4 227.9 18.1 14.7 23.9 58.8 24.0 63.6 13.5 39.1 56.5 19.4 10.2 31.6 47.3 11.9 40.1 16.4 19.9 45.8 21.3 156.7 153.0 147.4 179.9 158.9 134.8 140.4 144.6 136.6 134.8 143.9 145.2 52.1 6.4 5.4 9.4 35.3 32.9 14.7 26.7 35.3 61.6 77.8 66.9 0.3 31.5 14.5 11.0 12.5 26.8 106.7 111.5 29.4 31.6 2.5 58.5 59.0 41.0 133.3 90.3 12.8 41.9 55.6 46.3 34.7 39.6 33.0 103.1 30.7 37.7 57.5 47.1 13.0 103.6 32.6 47.8 47.8 6.6 28.0 47.6 46.2 8.4 26.4 35.6 50.4 9.5 14.2 36.3 68.5 36.9 41.6 32.8 37.8 21.9 25.6 35.1 32.9 30.1 49.1 22.2 24.5 38.6 35.5 16.7 67.5 70.9 126.8 14.9 MBD3 ENSG00000071655 "Methyl-CpG binding domain protein 3" O95983 19 1573596-1592865 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013265 Supported Supported Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB013265: " "unprognostic (1.41e-1)" "unprognostic (2.12e-2)" "unprognostic (3.44e-2)" "prognostic favorable (5.08e-4)" "unprognostic (1.85e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.99e-4)" "unprognostic (2.50e-1)" "unprognostic (3.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.76e-5)" "unprognostic (1.59e-1)" "unprognostic (1.19e-1)" "unprognostic (4.42e-2)" "unprognostic (5.89e-2)" "unprognostic (3.17e-1)" "unprognostic (4.24e-2)" 40.1 46.1 12.7 7.0 11.3 12.8 36.2 18.2 16.5 41.5 7.2 45.8 7.6 46.2 7.6 42.4 40.6 6.6 60.3 13.7 9.0 45.3 59.3 38.3 9.6 12.9 11.7 48.9 32.8 7.4 50.0 9.0 10.7 54.8 6.4 4.1 30.4 7.0 74.0 40.2 34.6 7.4 10.1 49.8 39.0 43.4 12.2 9.0 45.3 4.7 9.1 41.1 33.8 13.0 26.4 56.3 22.5 34.9 21.6 15.0 20.8 20.9 13.5 21.5 19.5 44.9 15.6 49.9 12.1 26.7 7.5 35.8 37.8 23.7 13.0 41.2 36.8 24.6 77.4 27.9 17.6 28.2 24.5 20.3 23.1 35.6 17.4 14.2 25.2 25.7 55.8 34.2 17.6 56.6 32.7 30.5 29.4 12.6 25.5 31.1 23.3 21.2 14.1 50.0 64.5 36.8 25.2 18.3 12.6 12.2 23.5 21.1 20.0 28.9 15.5 65.5 42.1 31.8 39.8 38.6 21.2 37.0 27.7 0.7 0.4 0.1 0.3 0.4 0.3 0.2 0.2 0.2 0.3 0.4 0.3 0.3 0.5 0.3 0.2 0.5 0.1 0.2 12.7 11.3 18.2 16.5 13.7 9.0 12.9 11.7 10.7 10.1 12.2 13.0 21.6 12.8 24.3 14.4 10.6 10.8 8.9 9.4 5.2 22.6 23.8 20.6 20.8 12.8 11.0 11.0 14.6 46.4 17.4 48.1 5.9 15.0 3.1 9.8 20.5 19.8 14.9 14.9 8.4 26.2 42.7 20.0 18.3 16.1 3.8 48.4 24.7 42.6 27.2 18.5 9.2 26.4 14.2 32.0 10.3 8.1 22.4 16.9 5.4 15.9 17.5 40.5 14.4 10.6 12.3 19.3 16.8 25.6 9.7 14.9 20.8 19.1 4.8 11.3 39.5 21.6 18.7 9.2 10.3 11.0 12.8 121.5 10.8 36.0 40.6 8.8 MCRS1 "ICP22BP, INO80Q, MCRS2, MSP58, P78" ENSG00000187778 "Microspherule protein 1" Q96EZ8 12 49556544-49568145 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039057 Supported Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA039057: AB_10794085" "unprognostic (2.60e-3)" "unprognostic (5.23e-2)" "unprognostic (1.46e-1)" "unprognostic (1.89e-2)" "unprognostic (1.68e-1)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (2.26e-2)" "unprognostic (2.83e-3)" "unprognostic (6.11e-2)" "unprognostic (9.94e-3)" "unprognostic (1.23e-1)" "prognostic favorable (2.70e-4)" "unprognostic (2.28e-1)" "unprognostic (1.69e-1)" "unprognostic (4.35e-2)" "unprognostic (3.26e-2)" 22.3 29.7 29.2 27.3 29.9 32.1 23.4 28.3 33.4 26.4 27.8 30.3 27.3 31.3 23.7 34.9 30.1 22.9 68.2 29.6 27.2 34.5 24.6 24.3 33.2 29.9 28.1 23.6 32.7 35.7 24.0 24.5 28.5 31.3 25.9 17.2 27.0 26.9 53.2 26.9 29.2 26.1 28.2 32.8 31.8 35.2 29.4 39.4 35.5 61.4 31.1 29.3 26.2 31.4 43.8 81.5 62.9 54.5 33.2 40.9 69.3 37.5 40.4 95.7 53.2 127.3 69.7 72.6 76.4 66.0 43.7 48.5 97.8 89.0 38.3 57.6 120.3 72.4 53.4 46.9 59.6 85.0 76.0 47.7 68.3 63.8 51.3 56.0 71.0 66.0 90.9 48.0 55.4 77.8 59.1 51.1 87.4 40.7 60.1 69.1 50.7 84.0 59.4 40.3 60.6 63.5 40.8 51.7 36.5 42.8 84.4 101.7 51.6 45.8 58.4 44.7 56.7 47.3 50.9 69.2 60.1 49.8 27.8 96.2 63.7 76.4 63.2 82.7 49.1 44.5 53.6 68.1 79.1 46.1 46.8 51.0 31.8 90.7 64.7 53.5 60.4 76.3 29.2 29.9 28.3 33.4 29.6 27.2 29.9 28.1 28.5 28.2 29.4 31.4 17.0 35.3 13.8 6.2 23.3 10.7 25.1 38.5 10.8 15.6 19.8 19.7 24.2 28.6 22.4 23.9 8.4 52.1 22.1 34.3 52.8 37.7 32.1 16.3 15.3 17.4 27.5 35.1 12.8 36.1 51.8 20.2 39.8 15.7 27.3 24.3 15.0 10.5 40.6 23.5 12.6 27.2 28.5 22.0 12.5 37.8 27.4 20.9 28.4 9.4 38.0 28.1 40.2 7.1 12.3 39.7 37.1 27.1 24.3 26.7 34.1 45.4 22.8 20.5 6.6 14.7 26.9 41.6 64.0 27.4 12.6 59.2 25.6 23.7 33.8 27.0 MED16 "DRIP92, THRAP5, TRAP95" ENSG00000175221 "Mediator complex subunit 16" Q9Y2X0 19 867630-893218 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030685, HPA046495" Uncertain Approved Nucleoli NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA030685: AB_10601872, HPA046495: AB_2679674" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (2.91e-1)" "prognostic favorable (5.46e-4)" "unprognostic (1.90e-1)" "unprognostic (5.25e-3)" "unprognostic (1.68e-1)" "unprognostic (1.61e-1)" "unprognostic (2.80e-1)" "unprognostic (3.15e-2)" "unprognostic (4.93e-3)" "unprognostic (3.28e-1)" "prognostic favorable (1.11e-5)" "unprognostic (4.83e-2)" "unprognostic (5.52e-1)" "unprognostic (1.57e-1)" "unprognostic (5.17e-2)" 49.7 38.2 33.8 19.4 32.9 13.9 41.1 27.0 57.4 46.9 24.3 38.2 15.4 34.6 1.9 44.3 35.0 11.8 34.9 33.4 29.5 44.2 68.6 32.7 16.2 32.9 31.3 44.3 55.3 12.8 39.3 13.5 29.0 54.1 5.8 5.0 36.1 10.1 44.5 43.0 35.7 8.6 28.5 46.0 39.7 36.4 32.8 10.5 38.2 10.0 7.5 45.0 41.3 29.6 29.4 25.1 24.7 17.0 10.2 10.8 27.5 20.3 19.1 29.7 22.4 32.6 27.3 29.8 23.6 18.1 9.9 23.4 9.3 24.3 5.0 37.8 29.6 29.9 18.5 30.4 20.3 29.0 26.6 18.9 12.1 18.2 11.7 17.4 23.1 31.5 36.3 69.8 17.9 44.5 47.3 34.1 38.3 11.0 33.5 48.1 17.9 38.3 20.5 45.3 30.6 29.5 27.2 18.3 22.5 9.2 21.4 22.3 22.4 30.1 30.2 46.3 23.6 50.6 19.8 28.4 39.2 27.2 22.7 53.0 31.5 40.7 50.2 34.2 45.4 53.7 56.0 57.8 40.7 44.0 46.2 43.8 44.1 40.4 36.6 27.3 82.3 52.7 33.8 32.9 27.0 57.4 33.4 29.5 32.9 31.3 29.0 28.5 32.8 29.6 15.5 35.3 24.8 6.5 19.0 11.6 11.3 15.6 12.0 15.9 16.9 17.7 7.1 15.7 15.2 22.0 6.2 62.6 11.9 57.5 17.6 24.4 3.6 15.5 16.9 15.2 25.7 14.1 3.2 24.3 32.3 19.4 44.9 27.3 14.5 32.4 14.6 24.0 25.3 15.2 2.6 34.8 18.3 16.1 5.7 6.5 13.7 14.6 10.6 4.7 23.8 15.8 12.3 3.0 4.7 23.0 29.4 14.7 23.2 11.3 34.6 17.4 12.9 20.4 6.6 12.3 16.4 13.9 28.8 12.0 16.1 63.8 19.7 30.4 34.1 15.0 MEF2D ENSG00000116604 "Myocyte enhancer factor 2D" Q14814 1 156463727-156500779 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 170.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 211.3;U-266/70: 193.0;U-266/84: 214.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004807, HPA007114" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA004807: AB_1079354, HPA007114: AB_1079353" "unprognostic (3.17e-2)" "unprognostic (7.31e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-2)" "unprognostic (1.95e-1)" "unprognostic (8.99e-2)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (9.96e-2)" "unprognostic (1.96e-2)" "unprognostic (1.97e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (7.53e-4)" "unprognostic (9.27e-2)" "unprognostic (1.66e-1)" "unprognostic (8.09e-3)" "unprognostic (1.45e-1)" 33.3 32.6 15.7 24.4 22.6 79.8 27.5 21.8 24.9 43.5 0.0 43.6 16.0 48.9 14.3 19.2 39.1 20.2 54.9 24.1 4.8 17.8 19.6 37.0 21.1 1.3 3.2 44.5 31.6 27.9 26.1 22.9 1.0 31.1 13.9 50.0 21.6 24.1 170.9 32.8 27.0 25.6 1.5 29.4 28.2 14.7 2.7 27.5 25.2 69.2 14.8 33.8 32.8 14.0 19.7 32.2 7.2 10.7 15.6 22.2 12.4 26.1 29.6 12.0 12.5 10.4 24.1 42.5 30.3 31.4 12.7 18.8 8.2 13.2 7.1 65.7 11.6 10.8 42.1 6.2 19.2 25.6 32.8 24.5 21.6 21.0 27.9 24.8 22.5 13.5 8.6 72.7 19.1 16.6 18.6 56.4 10.6 10.2 20.5 80.6 16.5 48.3 10.4 8.7 12.0 19.2 24.1 48.2 39.6 13.4 13.7 211.3 40.2 29.1 29.3 22.1 19.7 193.0 214.3 81.3 24.5 19.2 15.9 1.1 1.4 1.7 1.3 0.7 1.5 1.1 0.9 1.2 1.0 1.0 0.5 0.8 5.3 1.1 1.4 5.8 1.3 0.7 15.7 22.6 21.8 24.9 24.1 4.8 1.3 3.2 1.0 1.5 2.7 14.0 21.8 6.4 18.6 21.9 29.8 37.2 10.9 10.6 25.6 82.3 25.2 19.7 42.0 17.2 16.2 1.8 173.0 5.0 72.5 60.6 0.0 7.7 2.5 26.4 26.0 24.0 21.5 11.0 28.7 11.1 4.9 25.1 25.0 43.1 3.8 9.0 22.9 13.2 18.0 70.7 18.8 32.2 8.2 25.4 64.1 4.4 31.4 35.5 14.2 20.6 17.7 19.0 33.0 13.0 20.2 25.8 46.3 32.4 44.6 19.7 17.2 3.4 9.1 85.3 98.6 48.8 46.1 5.1 10.7 16.6 38.1 15.3 33.1 11.0 14.0 19.3 MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 565.4;Distal enterocytes: 398.7;Pancreatic endocrine cells: 535.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Cell line enhanced" "Detected in many" "BJ: 209.1;BJ hTERT+: 238.6;LHCN-M2: 191.3;RPTEC TERT1: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 174.8 16.1 100.8 22.9 91.0 18.9 92.0 87.2 123.4 26.8 48.0 81.9 36.9 17.7 9.9 139.9 34.3 44.8 101.9 96.9 75.9 71.0 106.9 72.0 13.5 72.5 86.6 6.1 7.8 3.6 12.5 41.6 70.9 25.8 60.4 6.2 102.1 27.5 66.0 38.1 50.3 27.8 63.0 44.9 38.2 6.2 107.2 10.0 18.9 64.9 21.3 42.5 39.4 88.6 52.4 46.2 0.1 0.5 76.8 90.0 6.2 209.1 238.6 45.3 72.2 1.2 21.0 14.0 56.9 71.3 13.7 2.1 0.4 27.9 25.2 23.5 0.9 1.6 31.4 0.4 27.7 0.3 1.7 34.2 16.1 85.0 92.4 25.6 97.5 1.0 0.3 3.0 191.3 5.6 0.5 0.9 0.5 33.6 71.5 0.2 24.6 109.4 170.4 5.9 26.5 2.1 36.3 70.4 12.6 2.0 3.5 2.1 125.9 49.5 14.8 121.0 29.1 0.5 0.4 43.4 102.4 3.4 156.6 20.6 8.3 36.0 0.5 84.7 2.8 4.9 0.5 1.1 9.2 0.5 0.2 0.2 1.5 2.0 57.2 89.8 0.0 17.1 100.8 91.0 87.2 123.4 96.9 75.9 72.5 86.6 70.9 63.0 107.2 88.6 565.4 195.5 108.6 83.2 8.5 22.8 11.9 14.1 5.7 22.8 25.2 19.9 53.7 118.7 32.2 42.3 0.0 84.6 16.1 398.7 168.3 99.4 4.1 100.0 36.4 207.7 88.6 30.7 39.0 160.7 154.6 71.5 47.9 132.1 8.8 0.1 17.2 148.7 123.9 0.0 48.9 239.1 63.1 32.8 86.3 5.8 32.6 77.8 21.4 52.5 235.2 54.5 2.1 43.2 5.8 535.2 201.0 69.6 36.2 18.5 134.2 102.0 48.0 7.8 85.5 22.3 141.4 0.7 1.7 64.7 22.3 72.7 9.3 1.1 74.0 6.0 MICALL2 "FLJ23471, JRAB, MGC46023, MICAL-L2" ENSG00000164877 "MICAL like 2" Q8IY33 7 1428465-1459470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 103.2;Distal enterocytes: 85.4;Gastric mucus-secreting cells: 171.8;Proximal enterocytes: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 27.7;OE19: 30.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA025695 Enhanced NA NA "Cluster 64: Macrophages - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA025695: AB_10610140" "unprognostic (2.46e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-2)" "unprognostic (6.01e-3)" "unprognostic (2.23e-3)" "unprognostic (3.51e-2)" "unprognostic (9.02e-3)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (6.40e-2)" "unprognostic (1.03e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (6.53e-9)" "unprognostic (1.95e-1)" "unprognostic (4.63e-2)" "unprognostic (1.46e-1)" "unprognostic (3.84e-2)" 4.9 18.4 1.0 4.9 0.2 7.6 4.7 0.5 2.4 6.8 0.0 13.9 12.4 5.2 0.2 8.2 5.5 3.4 4.9 0.8 0.3 8.1 5.4 7.9 2.2 0.3 1.5 1.4 4.6 0.7 6.6 0.7 0.4 9.5 1.8 0.0 8.3 2.1 1.5 6.8 18.6 2.2 0.0 15.4 12.8 2.7 1.2 1.7 6.7 0.0 1.0 9.8 6.2 0.9 16.6 1.8 0.5 2.2 1.7 4.2 4.5 7.6 2.9 3.4 1.2 2.2 6.3 0.3 4.6 2.4 6.9 9.4 0.0 8.8 0.2 1.2 2.0 11.0 3.0 1.3 2.1 0.5 27.7 5.5 2.0 2.4 0.3 2.1 3.9 1.5 18.3 0.5 1.6 17.4 0.4 17.6 1.5 30.2 5.3 2.9 3.1 11.7 2.3 4.5 0.4 1.5 6.3 11.5 6.0 0.7 9.6 6.3 13.4 2.5 19.6 9.3 7.7 0.8 0.2 0.0 8.1 6.0 16.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.5 2.4 0.8 0.3 0.3 1.5 0.4 0.0 1.2 0.9 5.3 3.2 10.8 103.2 2.0 8.7 7.0 39.0 16.5 1.9 13.2 10.9 7.7 18.6 22.5 14.7 2.1 0.5 1.9 85.4 1.9 11.4 5.9 13.5 7.7 10.0 6.0 7.8 13.0 15.4 6.6 9.9 171.8 14.3 5.7 5.4 10.4 3.2 3.3 3.3 10.0 49.0 18.3 3.5 6.2 5.3 4.1 3.3 3.6 4.7 2.3 1.2 0.0 29.1 5.7 18.4 51.9 0.4 1.5 12.8 70.2 1.5 25.3 1.6 6.6 4.1 11.4 5.3 6.2 14.6 6.1 1.2 1.7 3.3 36.9 8.0 MIER1 "hMI-ER1, KIAA1610, MI-ER1" ENSG00000198160 "MIER1 transcriptional regulator" Q8N108 1 66924895-66988619 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 97.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019589, HPA050306" Enhanced Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA019589: AB_1853953, HPA050306: AB_2681080" "unprognostic (3.38e-3)" "unprognostic (1.34e-1)" "prognostic favorable (4.96e-4)" "unprognostic (1.63e-1)" "prognostic favorable (3.44e-8)" "unprognostic (1.61e-1)" "unprognostic (3.15e-3)" "unprognostic (1.32e-1)" "unprognostic (1.05e-1)" "unprognostic (3.92e-3)" "unprognostic (4.48e-3)" "unprognostic (2.57e-2)" "unprognostic (2.81e-2)" "unprognostic (2.25e-2)" "unprognostic (2.73e-1)" "unprognostic (5.15e-2)" "unprognostic (2.45e-2)" 18.6 20.8 10.7 18.4 12.4 97.9 16.5 12.8 13.8 19.7 10.4 27.5 15.5 18.7 13.5 16.6 13.1 18.8 11.4 8.9 11.6 16.2 24.6 16.3 20.7 11.4 10.8 20.7 9.1 12.3 7.8 20.2 12.1 14.4 23.5 18.9 11.3 17.1 8.2 12.6 16.1 17.9 11.0 20.0 18.8 18.2 10.9 24.4 14.1 13.1 19.6 18.5 11.8 14.8 29.7 16.8 20.4 36.8 41.9 27.2 22.7 30.3 33.5 29.7 32.1 13.7 17.7 29.8 11.1 34.3 26.7 19.2 24.9 33.1 42.5 34.6 19.3 65.2 44.0 21.8 33.2 52.5 36.9 28.2 24.5 33.3 34.3 34.5 32.9 35.6 34.6 25.6 35.6 9.4 76.0 18.8 29.2 13.4 10.8 32.7 49.1 20.4 25.5 32.6 12.0 23.7 45.5 27.9 29.8 19.3 14.4 34.2 39.7 34.5 24.2 33.7 28.4 31.8 31.6 42.5 28.1 22.5 21.2 43.7 10.9 26.8 18.5 12.4 21.5 11.2 16.4 16.5 8.6 13.1 16.6 16.3 37.1 15.8 20.8 11.7 15.1 8.7 10.7 12.4 12.8 13.8 8.9 11.6 11.4 10.8 12.1 11.0 10.9 14.8 77.4 16.0 45.7 40.8 65.7 48.3 40.5 37.3 51.2 37.7 45.9 44.7 32.9 35.8 35.0 27.6 25.0 41.6 92.1 125.7 45.0 36.8 55.3 54.3 56.8 54.7 42.1 50.1 50.6 40.6 26.8 62.8 34.1 70.6 92.4 48.9 40.4 50.3 22.2 40.4 48.6 54.6 34.6 45.6 38.3 49.3 81.4 56.1 14.2 46.9 69.8 68.7 86.5 40.7 83.8 54.1 77.7 93.3 48.1 52.4 41.3 34.1 35.2 48.5 78.9 64.7 77.5 53.0 62.9 42.0 34.7 34.3 97.1 35.7 53.5 60.4 MIER3 "DKFZp686L09111, DKFZp781I1119, FLJ35954" ENSG00000155545 "MIER family member 3" Q7Z3K6 5 56919602-56971675 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Distal enterocytes: 128.8;Paneth cells: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058349, HPA065946" Uncertain Enhanced Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA058349: AB_2683688, HPA065946: AB_2685583" "unprognostic (1.01e-1)" "unprognostic (2.71e-1)" "unprognostic (4.07e-3)" "unprognostic (1.81e-1)" "unprognostic (2.22e-2)" "unprognostic (1.29e-1)" "unprognostic (2.82e-2)" "unprognostic (2.47e-1)" "unprognostic (1.61e-2)" "unprognostic (3.36e-1)" "unprognostic (1.88e-2)" "unprognostic (5.66e-2)" "unprognostic (9.31e-3)" "unprognostic (5.53e-2)" "unprognostic (3.76e-1)" "unprognostic (2.63e-2)" "unprognostic (4.84e-3)" 6.8 6.8 4.5 7.4 5.7 11.0 8.8 12.7 6.4 8.0 4.4 30.6 22.8 10.1 8.8 6.3 7.4 6.3 5.1 3.7 5.2 7.5 11.1 5.2 8.5 4.9 4.9 11.7 8.2 12.5 4.7 6.9 5.2 8.1 22.0 16.9 5.9 6.6 6.3 6.5 15.5 9.1 4.7 6.8 7.2 15.8 4.6 10.0 9.1 10.7 7.9 7.5 6.0 8.1 10.0 14.2 19.5 36.9 12.8 10.0 26.9 9.2 11.9 17.1 19.0 22.9 8.3 10.7 10.8 10.8 15.6 12.3 24.9 9.8 18.3 5.7 11.4 9.2 17.6 11.0 9.6 12.6 18.3 11.7 12.2 12.7 10.6 10.5 11.3 13.0 12.2 17.9 10.0 11.0 19.3 14.5 15.5 4.5 8.3 31.9 18.4 11.1 8.2 19.7 16.2 25.8 28.0 10.2 14.2 15.5 14.8 12.0 10.9 4.9 15.2 8.8 16.8 11.1 16.0 26.7 9.3 9.6 10.9 0.2 0.9 1.6 1.1 1.6 1.6 1.3 0.9 2.0 1.3 1.3 1.5 1.1 0.8 1.5 1.2 1.6 0.9 1.3 4.5 5.7 12.7 6.4 3.7 5.2 4.9 4.9 5.2 4.7 4.6 8.1 7.7 16.0 5.4 14.0 7.8 13.5 4.7 4.6 13.1 8.0 11.1 5.8 8.2 11.5 6.7 3.7 14.6 3.9 8.5 128.8 5.9 4.0 15.4 12.0 13.6 7.5 12.0 1.7 11.5 5.9 3.6 8.8 5.1 15.5 4.5 8.3 7.5 9.1 4.1 10.1 12.1 17.4 10.2 5.5 10.7 8.5 5.9 6.2 1.8 14.0 8.6 7.1 5.2 17.6 18.1 7.1 78.7 8.6 9.0 9.4 18.1 6.1 5.9 13.9 13.1 10.8 10.7 11.3 6.0 6.6 9.8 6.8 8.4 4.8 14.0 8.0 MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 793.4;Intestinal goblet cells: 230.9;Paneth cells: 646.7;Proximal enterocytes: 1115.2;Undifferentiated cells: 220.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 121.4;HaCaT: 90.2;hTCEpi: 82.6;MCF7: 63.2;OE19: 76.9;SK-BR-3: 134.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" 1.3 0.0 0.3 12.1 0.3 0.0 0.9 0.5 0.4 4.4 0.1 95.5 171.0 0.7 0.0 0.3 9.8 11.3 0.0 0.4 0.3 8.8 0.1 9.3 0.1 0.5 0.5 0.3 1.7 0.0 8.1 1.2 0.5 5.6 48.4 0.0 1.0 0.5 0.0 0.6 196.6 3.3 0.2 0.0 22.9 0.5 0.3 0.3 0.1 0.0 0.0 9.0 0.6 0.2 30.4 121.4 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 42.1 44.2 10.8 11.5 0.0 0.1 90.2 0.0 37.7 0.0 0.0 0.1 0.0 47.0 13.3 0.0 0.0 1.9 0.0 82.6 0.3 4.5 0.0 0.0 0.0 0.0 0.4 0.2 63.2 0.1 0.7 0.1 76.9 24.6 0.2 0.4 1.0 30.1 33.7 1.4 0.4 42.9 134.3 0.1 0.1 29.3 0.0 0.0 0.0 14.8 1.8 0.2 0.6 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.4 0.3 0.5 0.5 0.5 0.2 0.3 0.2 0.1 38.5 8.0 0.3 2.9 0.1 4.5 22.5 0.0 0.0 4.7 2.3 0.5 10.0 39.7 11.0 0.0 0.6 0.0 793.4 1.9 39.9 0.6 40.5 1.5 0.8 58.0 0.0 0.2 46.0 6.0 2.4 56.6 14.3 8.9 0.0 0.0 0.0 0.1 0.0 0.3 230.9 28.5 0.0 0.0 0.9 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.2 157.7 646.7 0.0 0.1 41.6 1115.2 27.5 41.3 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.3 2.1 1.6 0.0 220.7 62.1 MLEC KIAA0152 ENSG00000110917 Malectin Q14165 12 120687149-120701859 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Undifferentiated cells: 397.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 880000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.60e-6)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (5.41e-2)" "unprognostic (3.94e-1)" "unprognostic (3.39e-1)" "unprognostic (9.77e-2)" "unprognostic (5.90e-2)" "unprognostic (1.76e-1)" "unprognostic (1.15e-2)" "prognostic favorable (8.77e-4)" "unprognostic (1.98e-1)" "unprognostic (7.88e-2)" "unprognostic (1.05e-1)" 51.7 93.1 35.4 51.8 36.7 34.6 44.3 33.0 34.5 52.8 40.3 127.0 78.3 37.2 138.1 24.5 48.5 48.5 65.9 34.7 40.0 73.5 78.2 34.9 30.3 42.3 39.4 49.2 62.7 101.2 36.7 45.7 37.8 62.4 117.3 25.3 50.7 64.9 79.8 27.8 86.0 50.0 40.0 30.1 45.3 69.1 42.9 33.3 101.0 82.9 37.3 34.1 17.4 37.6 122.7 177.9 113.6 151.8 196.3 107.4 127.9 144.5 126.3 108.9 80.1 127.5 75.1 100.3 129.0 142.2 85.4 101.9 140.4 87.4 138.7 86.5 76.9 142.4 79.4 100.6 72.1 199.3 123.1 82.2 82.7 116.0 91.4 174.1 97.2 93.9 85.9 112.2 116.3 127.8 106.4 122.2 158.1 156.6 91.7 115.7 82.0 109.1 132.2 204.0 58.2 69.2 166.5 85.9 86.0 143.0 127.0 144.6 79.2 115.8 108.5 112.8 100.3 83.3 165.0 76.8 147.6 147.9 120.1 0.5 6.0 8.0 3.8 7.5 4.1 4.7 2.3 3.4 5.0 6.9 4.0 3.4 1.6 3.9 6.5 18.6 2.4 2.2 35.4 36.7 33.0 34.5 34.7 40.0 42.3 39.4 37.8 40.0 42.9 37.6 151.4 25.6 62.2 23.2 65.7 72.8 70.6 32.0 55.2 40.9 99.7 76.3 145.3 97.2 40.0 86.5 45.9 88.4 105.7 155.3 37.2 134.2 243.3 78.3 127.6 94.1 80.3 68.5 21.4 183.7 176.9 90.5 69.3 80.2 49.5 99.8 27.1 206.1 126.8 84.1 24.7 199.2 30.5 61.7 73.2 228.0 82.6 70.1 193.9 34.7 56.4 81.8 74.2 32.2 23.0 95.8 86.0 108.0 217.4 152.6 135.4 121.7 41.9 45.3 85.5 61.4 78.5 165.6 153.4 52.8 58.7 115.6 51.2 142.5 397.0 82.2 MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.8;Distal enterocytes: 109.3;Proximal enterocytes: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 93.6;Hep G2: 51.1;OE19: 44.6;SK-BR-3: 47.3;WM-115: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" 11.9 3.8 8.9 4.4 6.0 0.4 7.6 7.3 11.2 5.7 5.8 28.0 40.2 3.5 1.1 4.6 6.1 14.3 41.2 6.9 8.7 14.9 50.1 9.9 2.1 15.8 10.6 1.1 18.5 12.7 8.8 28.4 16.8 4.4 14.3 1.5 8.4 9.5 7.0 4.3 33.0 3.7 5.8 9.3 29.6 34.9 18.7 1.0 46.7 5.6 1.3 5.1 2.8 8.6 15.3 11.4 5.8 30.4 6.0 0.3 93.6 1.4 0.8 5.4 1.2 9.1 38.3 0.2 17.7 1.6 4.2 21.0 5.1 4.4 1.6 0.1 10.0 0.1 4.9 51.1 7.7 0.3 19.5 3.1 7.8 0.9 2.3 8.4 3.7 8.5 12.9 0.1 1.8 7.6 0.7 2.6 17.2 44.6 3.2 7.6 0.7 8.3 16.6 5.4 1.6 10.4 20.0 47.3 9.5 13.2 5.2 8.2 3.4 0.4 9.1 3.5 1.3 0.2 0.1 0.3 1.9 2.3 78.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.9 6.0 7.3 11.2 6.9 8.7 15.8 10.6 16.8 5.8 18.7 8.6 14.3 19.2 14.4 9.1 0.7 2.5 1.0 4.9 2.8 3.4 5.0 3.0 24.7 55.8 12.6 18.4 16.7 48.2 1.6 109.3 1.9 35.7 5.0 3.6 1.1 17.2 11.4 2.7 1.4 12.0 49.2 4.5 35.2 6.4 0.0 18.6 13.6 39.2 12.9 1.7 1.2 33.3 10.2 3.0 0.3 6.9 0.9 0.9 1.8 1.0 0.0 2.1 0.0 4.5 1.4 13.3 38.5 3.4 0.3 1.3 67.3 7.3 6.0 1.9 0.0 0.7 2.4 0.9 4.6 3.3 2.3 48.4 0.7 23.2 45.0 1.7 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MNX1 "HB9, HLXB9, HOXHB9, SCRA1" ENSG00000130675 "Motor neuron and pancreas homeobox 1" P50219 7 156994051-157010663 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 7.2;pancreas: 16.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 6.6;Enteroendocrine cells: 25.1;Intestinal goblet cells: 19.7;Paneth cells: 7.0;Proximal enterocytes: 7.3;Undifferentiated cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 17.2;BEWO: 12.7;EFO-21: 16.2;HEK 293: 13.2;RPMI-8226: 37.6;SCLC-21H: 19.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 39 "spinal cord: 3.9" HPA071717 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Cytosol" "HPA071717: AB_2686437" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.87e-2)" "unprognostic (3.72e-3)" "unprognostic (8.85e-2)" "unprognostic (1.08e-2)" "unprognostic (2.07e-1)" "unprognostic (4.07e-2)" "unprognostic (5.06e-2)" "unprognostic (8.62e-4)" "unprognostic (1.00e-2)" "unprognostic (3.35e-2)" "unprognostic (2.23e-5)" "unprognostic (1.67e-3)" "unprognostic (5.80e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" 0.1 0.0 0.5 0.3 0.5 0.1 0.0 0.3 0.6 0.0 0.0 3.7 7.2 0.0 0.0 0.2 0.0 0.8 0.0 0.5 0.2 0.1 0.0 0.0 0.0 1.3 0.3 0.0 16.3 0.0 2.6 0.0 0.9 0.3 3.0 0.0 1.1 0.0 0.0 0.1 6.1 0.0 0.8 0.0 2.2 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.4 5.8 0.0 17.2 0.0 0.0 12.7 0.0 0.0 0.1 0.0 7.6 2.5 1.4 16.2 0.0 0.5 0.3 3.0 2.3 1.3 2.2 13.2 0.0 1.5 3.6 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 6.1 5.7 2.9 0.0 10.1 0.9 0.2 0.0 1.7 1.1 0.0 2.5 37.6 6.5 0.6 19.3 0.0 2.5 2.2 0.4 0.1 5.4 4.4 0.0 0.0 0.0 0.0 0.0 5.3 2.9 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 0.6 0.5 0.2 1.3 0.3 0.9 0.8 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.0 4.4 1.3 0.1 0.0 0.1 25.1 0.0 0.0 3.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 19.7 0.0 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 3.1 7.0 0.0 0.4 0.0 7.3 0.1 0.0 0.0 0.0 0.0 0.2 1.8 0.8 0.0 0.0 0.0 0.2 0.0 13.6 0.0 MOGAT3 "DC7, DGAT2L2, MGAT3" ENSG00000106384 "Monoacylglycerol O-acyltransferase 3" Q86VF5 7 101195007-101201038 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 24.4;liver: 18.9" "Group enriched" "Detected in some" 4 "Distal enterocytes: 81.9;Paneth cells: 56.3;Proximal enterocytes: 88.9;Undifferentiated cells: 26.3" "Group enriched" "Detected in many" 5 "colorectal cancer: 11.0;liver cancer: 11.1;stomach cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "CACO-2: 2.9;Hep G2: 10.7" HPA011940 Approved Approved Centrosome NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "HPA011940: AB_1854057" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (7.14e-2)" "unprognostic (6.11e-2)" "unprognostic (3.20e-1)" "unprognostic (9.54e-3)" "unprognostic (9.36e-2)" "unprognostic (3.08e-1)" "unprognostic (1.05e-3)" "unprognostic (1.87e-1)" "unprognostic (1.23e-1)" "unprognostic (9.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.59e-2)" 0.1 0.1 0.5 1.7 0.4 0.9 0.1 1.4 0.7 0.0 0.2 13.4 24.4 0.2 0.2 0.2 0.1 0.2 0.1 0.5 0.2 1.2 18.9 0.1 0.2 0.3 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.1 7.2 0.4 0.1 0.1 0.5 0.4 23.8 0.8 0.0 0.2 0.2 0.1 0.4 0.1 0.1 0.0 0.0 0.1 0.0 1.1 0.4 0.1 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 2.9 0.8 0.1 0.4 0.0 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.3 0.4 10.7 0.1 0.2 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.3 0.0 0.1 0.2 0.3 0.1 0.3 0.4 0.1 0.0 0.3 0.4 0.4 0.1 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.6 0.6 0.1 0.6 0.3 0.2 0.1 0.0 0.6 0.3 0.8 0.8 0.2 0.3 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.4 0.2 0.3 1.6 0.5 0.2 0.3 0.1 0.1 0.5 0.4 1.4 0.7 0.5 0.2 0.3 0.1 0.4 0.0 0.4 1.1 0.3 0.0 0.5 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 81.9 0.0 0.1 0.0 0.1 0.2 0.1 1.8 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 1.1 7.4 0.0 0.0 0.0 14.7 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 56.3 0.0 0.0 0.2 88.9 5.0 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.1 0.1 0.5 0.1 26.3 0.4 MPDU1 "CDGIf, Lec35, PQLC5, SL15, SLC66A5" ENSG00000129255 "Mannose-P-dolichol utilization defect 1" O75352 17 7583529-7592789 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 157.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014845 Uncertain Supported "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" Mitochondria "HPA014845: AB_1854072" "unprognostic (1.96e-1)" "unprognostic (8.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.36e-2)" "unprognostic (5.00e-2)" "unprognostic (5.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" "unprognostic (4.70e-2)" "unprognostic (3.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (2.34e-3)" "unprognostic (9.00e-2)" "unprognostic (2.60e-1)" "unprognostic (2.48e-3)" "unprognostic (2.93e-1)" 31.9 41.1 33.0 32.8 34.1 63.3 39.2 35.5 34.5 33.3 41.9 65.5 53.3 17.4 33.5 37.7 32.0 35.7 20.4 31.7 34.2 72.2 107.0 33.3 30.7 34.3 33.9 10.9 39.7 57.4 15.6 37.1 33.7 33.7 69.6 25.4 33.6 18.4 21.3 29.0 48.5 28.7 34.2 28.4 54.5 14.5 36.2 25.9 35.7 21.3 38.0 43.2 21.9 34.9 51.0 111.8 75.9 54.1 83.8 74.4 50.5 81.1 104.6 142.4 98.6 58.0 85.0 28.8 54.8 128.1 65.0 98.4 102.2 134.3 116.6 63.8 118.8 55.7 65.8 98.7 101.0 49.3 89.8 77.9 105.2 133.4 76.4 64.7 105.8 84.9 87.1 38.6 151.6 70.1 35.9 48.4 85.2 107.4 55.8 81.6 56.4 60.7 145.1 52.1 45.8 90.1 104.4 75.9 34.4 59.5 83.8 50.1 76.5 67.5 36.9 36.8 111.2 20.3 34.6 27.0 97.1 62.3 103.5 16.8 44.2 14.0 16.9 73.1 12.8 18.1 16.1 22.1 52.4 16.5 15.4 18.3 6.5 17.4 69.1 48.5 26.4 24.9 33.0 34.1 35.5 34.5 31.7 34.2 34.3 33.9 33.7 34.2 36.2 34.9 30.1 9.6 23.0 5.5 30.4 10.7 34.9 51.0 22.2 18.1 34.7 22.7 5.1 34.3 31.0 23.9 12.5 111.5 26.5 106.8 35.2 62.7 3.2 22.2 23.3 28.2 37.2 96.8 4.5 76.1 93.8 27.5 53.5 28.1 14.5 28.6 25.0 49.7 79.7 16.8 5.6 68.9 40.7 30.5 23.6 5.7 17.1 46.1 24.9 4.7 35.9 28.5 21.6 6.6 9.3 69.7 76.8 6.4 38.5 37.1 78.0 48.0 20.3 23.3 26.3 30.6 24.7 22.9 26.4 20.7 12.6 157.6 26.0 37.1 77.1 40.9 MPND FLJ14981 ENSG00000008382 "MPN domain containing" Q8N594 19 4343527-4360086 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 84.7;Paneth cells: 42.7;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043274, HPA045475" Approved Approved "Nucleoplasm,Nucleoli rim" No No "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli rim" Nucleoplasm "HPA043274: AB_2678403, HPA045475: AB_2679339" "unprognostic (3.16e-2)" "prognostic favorable (2.99e-4)" "unprognostic (4.85e-2)" "prognostic favorable (6.12e-4)" "unprognostic (8.60e-2)" "unprognostic (5.37e-3)" "unprognostic (3.16e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.23e-1)" "unprognostic (2.87e-2)" "unprognostic (3.94e-3)" "unprognostic (5.18e-2)" "prognostic favorable (7.04e-4)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (5.44e-2)" "unprognostic (9.04e-2)" 10.5 21.9 22.6 9.3 22.4 15.8 10.7 27.1 35.0 13.2 20.8 25.4 30.6 11.9 8.6 18.1 11.5 9.5 22.4 23.1 20.5 22.7 46.5 12.6 11.7 22.7 20.7 13.0 24.4 15.4 11.0 6.9 23.3 19.0 16.2 4.0 17.2 9.6 23.2 15.6 19.8 6.5 19.4 15.2 20.1 6.6 20.6 10.2 13.3 14.4 7.1 15.2 12.7 25.0 16.0 13.2 21.3 24.6 13.1 6.1 21.7 7.6 7.2 6.2 7.6 25.6 8.1 14.4 23.3 9.9 18.2 16.1 9.8 13.2 3.4 16.4 21.5 11.0 18.4 37.4 10.0 14.9 19.1 9.4 9.4 6.8 7.1 9.3 18.9 37.4 6.0 36.4 7.8 41.8 35.4 12.6 9.8 26.5 18.2 28.8 6.5 21.0 15.5 25.4 23.7 24.3 13.5 19.4 9.9 12.1 13.0 18.1 7.3 9.8 10.4 60.4 15.4 30.1 20.1 9.7 10.9 8.3 11.5 9.3 3.1 1.5 1.3 3.7 2.1 1.0 1.6 1.9 2.9 1.6 1.0 1.1 0.8 1.7 1.8 2.9 3.7 1.3 22.6 22.4 27.1 35.0 23.1 20.5 22.7 20.7 23.3 19.4 20.6 25.0 6.1 0.0 3.7 1.6 5.1 5.4 8.4 1.4 3.4 8.2 9.5 8.5 13.9 11.5 2.7 11.0 2.1 13.6 9.8 84.7 0.0 4.1 0.8 8.0 6.1 6.0 16.7 2.5 2.6 5.1 11.9 5.2 9.2 8.9 4.5 7.8 5.7 23.5 14.8 6.7 2.4 31.2 2.0 26.0 9.6 3.9 6.2 14.4 3.6 1.9 8.8 8.6 21.6 3.5 2.1 4.3 42.7 3.8 7.7 6.9 50.7 15.0 2.3 5.6 6.6 6.1 11.7 0.2 7.6 7.8 8.4 10.4 6.3 9.1 34.6 9.6 MROH6 C8orf73 ENSG00000204839 "Maestro heat like repeat family member 6" A6NGR9 8 143566192-143572772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 23.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.8;Hepatocytes: 13.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 11.6;HaCaT: 13.6;OE19: 14.8;SK-BR-3: 30.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA068049 Uncertain Approved Nucleoplasm NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA068049: AB_2685945" "unprognostic (2.10e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-3)" "unprognostic (2.26e-3)" "unprognostic (8.04e-2)" "unprognostic (8.96e-2)" "unprognostic (2.28e-1)" "unprognostic (1.73e-1)" "unprognostic (5.97e-2)" "unprognostic (2.81e-2)" "unprognostic (1.09e-2)" "unprognostic (9.04e-2)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (1.44e-1)" "unprognostic (9.16e-3)" "unprognostic (1.18e-1)" 2.5 3.1 1.1 0.5 1.2 1.7 2.1 1.2 1.4 6.5 1.0 4.5 2.0 2.4 0.1 23.4 2.4 0.7 1.4 1.2 0.9 3.7 7.4 4.0 0.3 1.2 1.2 3.2 1.1 0.2 1.9 0.2 1.1 2.8 0.0 0.1 4.2 0.4 0.9 13.9 5.0 0.1 1.0 4.6 2.9 5.8 1.2 0.3 1.7 0.1 0.7 3.3 8.5 1.0 11.6 2.0 0.2 0.4 0.7 0.7 0.5 0.5 0.4 0.5 0.2 0.4 6.0 1.1 0.6 0.2 0.0 13.6 0.0 2.7 0.0 1.2 1.2 1.3 4.3 0.3 0.6 0.5 1.1 0.7 0.7 0.0 0.0 0.0 0.2 0.4 0.6 0.7 0.0 2.8 0.6 0.3 0.0 14.8 1.1 0.7 0.4 1.1 0.7 1.1 0.2 0.3 0.6 30.0 0.7 0.0 1.3 0.9 0.0 0.4 3.9 0.7 1.2 0.5 0.4 0.3 0.5 6.8 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 1.2 1.2 1.4 1.2 0.9 1.2 1.2 1.1 1.0 1.2 1.0 4.0 0.0 4.7 3.9 1.6 2.8 2.2 1.4 4.0 1.4 7.2 4.3 1.5 7.2 2.7 9.2 0.0 1.0 3.7 13.8 1.9 1.3 0.0 1.5 2.9 2.4 1.8 6.1 1.4 0.7 3.4 3.0 6.6 3.0 1.3 3.6 1.1 13.4 5.2 1.7 1.3 4.5 0.0 8.1 3.7 1.3 4.7 6.0 3.6 0.0 3.3 3.5 4.1 0.5 0.3 7.2 6.0 2.6 3.1 2.1 7.3 2.3 0.9 0.3 0.0 2.8 2.3 0.7 7.6 3.2 2.6 1.0 2.6 2.3 8.2 2.8 MRPL12 "MRPL7, MRPL7/L12, RPML12" ENSG00000262814 "Mitochondrial ribosomal protein L12" P52815 17 81703367-81707517 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 303.2;Undifferentiated cells: 364.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022853, HPA023043" Supported Supported Mitochondria NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA022853: AB_1854099, HPA023043: AB_1854100" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (6.59e-2)" "unprognostic (1.66e-2)" "unprognostic (9.52e-2)" "unprognostic (5.97e-2)" "unprognostic (5.97e-3)" "prognostic unfavorable (2.35e-4)" "unprognostic (1.78e-1)" "unprognostic (6.47e-3)" "unprognostic (8.17e-2)" "unprognostic (3.07e-1)" "unprognostic (8.77e-3)" "unprognostic (3.41e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (9.26e-2)" 57.8 73.7 39.4 28.4 39.9 31.0 44.0 46.8 51.9 34.4 50.4 79.7 47.3 39.1 11.0 96.8 35.1 10.9 209.9 39.0 42.2 86.9 184.9 34.9 25.5 40.7 43.1 26.7 60.6 45.9 39.1 19.5 41.0 44.9 37.3 7.3 48.1 21.5 169.7 51.1 51.3 20.6 38.8 53.8 57.9 32.3 46.2 20.1 34.0 148.1 27.7 45.4 46.5 39.4 153.6 256.8 67.5 78.2 50.2 55.0 124.3 117.0 71.3 173.2 128.3 216.5 71.6 236.5 69.2 77.5 116.7 127.1 87.6 150.7 87.6 55.9 438.3 181.1 140.2 246.5 74.0 200.5 90.9 63.4 108.5 119.4 132.4 55.4 146.1 115.6 179.4 75.6 87.1 194.2 171.6 295.9 106.0 165.9 330.6 160.7 109.5 176.4 129.8 126.1 171.4 220.7 86.1 366.1 199.8 69.1 186.2 180.5 76.7 131.0 155.8 103.4 241.2 146.2 54.3 137.0 89.3 143.0 100.6 17.7 63.1 9.0 37.9 84.8 52.6 66.2 37.8 42.6 93.7 62.1 39.2 36.0 6.9 43.5 49.8 77.0 35.8 48.9 39.4 39.9 46.8 51.9 39.0 42.2 40.7 43.1 41.0 38.8 46.2 39.4 43.0 19.2 12.8 4.9 42.2 53.3 83.7 101.7 8.6 17.1 67.2 85.0 88.7 84.4 47.6 46.0 4.2 172.4 29.1 303.2 219.2 113.0 38.9 40.6 39.8 47.8 104.0 40.4 4.5 118.5 187.2 38.9 28.5 33.6 30.5 75.7 39.7 223.4 167.0 23.5 6.0 257.7 44.7 62.2 34.5 127.2 39.4 36.8 58.7 1.9 59.7 29.7 45.3 3.0 4.6 126.5 126.9 32.7 24.4 137.1 196.2 258.5 35.0 17.3 32.9 30.8 65.1 46.5 56.9 30.1 60.5 112.5 25.2 126.0 364.0 109.8 MRPL23 "L23MRP, RPL23L" ENSG00000214026 "Mitochondrial ribosomal protein L23" Q16540 11 1947278-1984522 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 342.1" HPA050406 Approved Supported "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Nucleoli fibrillar center" "HPA050406: AB_2681116" "unprognostic (5.74e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-2)" "unprognostic (2.08e-1)" "unprognostic (2.40e-1)" "unprognostic (2.56e-1)" "unprognostic (2.34e-2)" "unprognostic (8.32e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (1.82e-1)" "unprognostic (6.33e-2)" "unprognostic (7.23e-3)" "unprognostic (4.08e-2)" 67.5 123.1 18.3 16.4 19.2 42.4 66.3 19.4 26.0 64.2 20.3 74.8 27.1 54.0 14.3 125.9 57.8 10.9 128.4 18.8 20.1 96.6 140.1 67.4 26.7 19.7 18.7 90.8 118.0 23.5 92.3 8.5 19.6 71.8 19.1 7.0 90.4 14.6 159.5 124.0 67.1 13.1 19.3 81.7 94.3 27.1 19.0 17.7 71.5 39.6 23.9 59.7 70.9 20.5 69.3 74.9 39.7 49.2 15.9 44.0 67.4 20.9 28.0 31.8 23.4 4.8 79.2 72.9 43.6 44.4 44.5 70.6 64.5 88.8 15.0 75.4 342.1 28.1 24.5 98.2 41.7 65.2 40.8 34.9 34.0 22.0 6.4 37.3 23.0 38.3 24.9 34.6 46.5 71.4 57.9 55.8 64.1 58.5 71.9 77.7 27.2 92.0 28.4 25.0 86.5 81.6 25.0 56.2 45.6 22.0 1.4 78.1 30.8 43.6 32.4 11.0 44.0 58.4 47.7 68.7 68.2 56.0 0.1 2.7 18.5 16.8 8.0 14.5 6.4 36.4 11.8 9.4 23.9 34.6 25.7 8.1 1.0 8.3 10.4 10.6 20.0 5.2 18.3 19.2 19.4 26.0 18.8 20.1 19.7 18.7 19.6 19.3 19.0 20.5 33.9 12.8 6.3 17.0 79.1 186.3 69.9 154.6 19.4 7.0 105.4 111.6 69.7 95.8 88.7 38.6 0.0 125.3 43.6 298.1 123.3 126.6 10.2 57.9 29.1 37.5 136.2 117.8 9.4 232.6 224.4 43.3 54.6 40.2 96.6 54.7 57.8 178.9 178.5 5.0 9.9 258.7 99.7 163.9 214.3 18.5 23.0 78.4 200.9 3.7 133.6 30.6 63.8 7.5 12.2 171.1 273.6 36.5 76.8 61.9 175.4 245.0 98.7 11.7 39.5 33.5 69.2 24.4 39.8 47.5 258.7 90.6 50.2 67.0 256.1 82.8 MRPS18A "FLJ10548, MRPS18-3" ENSG00000096080 "Mitochondrial ribosomal protein S18A" Q9NVS2 6 43671202-43687791 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 370.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035450, HPA035451" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA035450: AB_10670701, HPA035451: AB_10602029" "unprognostic (9.85e-2)" "unprognostic (3.08e-1)" "unprognostic (2.04e-1)" "unprognostic (7.35e-3)" "unprognostic (2.00e-1)" "unprognostic (1.15e-2)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (5.16e-2)" "unprognostic (1.41e-2)" "unprognostic (3.86e-2)" "unprognostic (9.15e-2)" "unprognostic (2.14e-2)" "unprognostic (2.42e-1)" "unprognostic (1.96e-1)" "prognostic favorable (4.03e-5)" "unprognostic (9.35e-2)" 34.5 44.1 37.0 21.0 37.9 21.5 33.3 37.8 43.4 31.5 53.8 42.6 36.3 32.4 20.9 58.3 30.1 20.4 66.7 39.2 37.7 46.9 63.3 25.6 22.7 38.8 38.1 21.9 32.3 39.1 19.5 22.7 37.7 39.5 45.4 15.0 35.1 26.8 149.4 41.7 31.3 27.1 38.2 32.1 56.1 17.5 39.4 26.4 28.4 103.4 33.1 34.8 33.9 38.1 71.0 57.7 45.2 63.9 45.2 30.4 51.4 32.9 50.2 78.6 77.3 118.7 28.4 29.6 55.4 46.0 64.1 56.6 64.3 92.5 40.9 45.6 76.5 55.7 44.3 104.5 78.1 76.1 32.4 41.4 73.5 66.6 100.6 40.2 59.9 73.0 97.9 61.4 47.0 115.2 58.3 63.4 33.6 370.3 46.2 48.8 35.9 95.9 59.1 79.9 72.5 38.9 34.7 64.5 121.8 32.1 65.5 106.7 32.6 49.4 56.4 40.2 60.2 67.1 60.2 110.3 66.2 52.8 134.8 106.6 69.8 76.8 79.1 60.9 74.8 135.4 73.6 76.0 82.3 98.3 73.0 67.9 32.5 93.3 45.2 91.2 86.9 84.1 37.0 37.9 37.8 43.4 39.2 37.7 38.8 38.1 37.7 38.2 39.4 38.1 27.1 32.1 24.5 5.2 31.8 33.4 44.6 97.7 12.0 13.6 29.1 26.4 1.3 30.0 61.2 33.1 2.1 72.7 15.6 96.0 99.7 78.2 16.5 26.2 26.2 25.3 32.3 23.5 5.1 67.4 64.0 24.6 56.6 43.7 26.6 28.8 30.4 51.8 51.1 8.4 4.5 73.4 73.2 17.5 19.8 35.2 22.7 16.5 40.9 7.5 51.7 23.4 29.9 9.0 5.2 69.3 94.2 21.1 42.9 45.0 73.4 115.4 34.7 15.5 32.9 24.7 25.8 27.3 36.2 31.0 27.3 67.5 19.5 61.7 97.2 77.9 MS4A12 "FLJ20217, Ms4a10" ENSG00000071203 "Membrane spanning 4-domains A12" Q9NXJ0 11 60492778-60507430 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 254.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 1139.3" "Cancer enriched" "Detected in some" 8 "colorectal cancer: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048616, HPA057657" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli, Endoplasmic reticulum, Golgi apparatus" "HPA048616: , HPA057657: AB_2683491" "unprognostic (2.64e-2)" "unprognostic (2.33e-1)" "unprognostic (1.49e-1)" "unprognostic (3.26e-1)" "unprognostic (2.83e-1)" "unprognostic (9.20e-3)" 0.2 0.0 0.0 10.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 234.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 254.3 0.0 0.0 0.5 0.0 0.0 0.3 4.8 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1139.3 0.0 0.0 0.4 0.1 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 255.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.6 0.1 27.8 0.0 MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.3;stomach 1: 42.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Distal enterocytes: 53.9;Gastric mucus-secreting cells: 108.6;Intestinal goblet cells: 25.7;Pancreatic endocrine cells: 31.2;Paneth cells: 30.3;Proximal enterocytes: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 39.3;CAPAN-2: 98.8;HaCaT: 56.3;HBEC3-KT: 59.4;hTCEpi: 83.4;RT4: 67.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" 5.1 0.3 1.1 5.1 1.1 0.2 3.8 1.1 1.7 5.7 1.3 26.5 25.2 1.3 1.2 17.5 1.7 11.4 3.2 1.1 0.9 3.4 1.1 9.5 2.5 0.9 0.8 1.0 5.8 0.1 2.7 0.8 0.9 4.7 20.1 0.2 5.4 1.0 1.3 62.3 23.9 2.0 0.8 1.6 42.6 8.4 0.9 8.8 3.4 0.7 5.6 9.2 11.5 1.0 39.3 14.4 0.1 0.6 0.0 0.0 2.2 0.5 0.1 0.0 0.0 4.1 98.8 1.7 8.8 0.5 0.1 56.3 0.0 59.4 0.0 0.9 1.0 0.1 25.9 0.9 0.9 0.0 1.2 0.3 83.4 0.2 11.7 0.2 0.1 0.2 0.8 0.3 0.0 5.1 0.1 0.1 0.3 33.1 34.6 2.9 0.0 1.1 35.8 67.9 1.0 0.1 11.5 22.6 0.2 0.1 17.7 0.9 0.3 0.0 0.3 0.3 0.1 0.5 0.2 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 1.1 1.1 1.7 1.1 0.9 0.9 0.8 0.9 0.8 0.9 1.0 1.6 25.6 10.3 0.7 1.0 8.8 2.2 14.2 6.8 0.0 2.8 2.5 1.0 0.0 10.6 0.0 0.0 0.1 0.2 53.9 0.0 6.4 15.4 2.9 0.8 0.6 4.2 0.0 1.1 10.0 0.4 0.8 108.6 5.3 0.0 0.1 0.0 0.0 0.1 0.0 1.1 25.7 2.0 0.0 1.4 10.5 0.3 0.5 0.0 1.0 0.6 0.0 1.0 2.0 0.1 31.2 30.3 0.0 0.5 2.2 27.6 0.1 7.6 0.0 0.0 0.5 0.9 1.3 1.5 3.2 4.7 0.0 0.5 0.0 20.1 6.2 MTMR11 CRA ENSG00000014914 "Myotubularin related protein 11" A4FU01 1 149928651-149936879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 139.2;Intestinal goblet cells: 79.2;Paneth cells: 98.9;Proximal enterocytes: 133.2;Undifferentiated cells: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.7;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 16 "dendritic cells: 1.7;monocytes: 1.3" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 17.0;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030351, HPA072906" Enhanced Approved Centrosome NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "HPA030351: AB_10602185, HPA072906: " "unprognostic (1.14e-1)" "unprognostic (3.01e-3)" "unprognostic (1.42e-1)" "unprognostic (1.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.37e-2)" "unprognostic (5.81e-2)" "unprognostic (7.94e-2)" "unprognostic (2.98e-1)" "unprognostic (2.88e-2)" "unprognostic (1.22e-1)" "unprognostic (5.83e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (1.80e-2)" "unprognostic (9.12e-2)" 3.6 12.3 3.5 2.9 3.6 0.1 4.1 3.2 4.0 11.0 7.3 22.2 20.3 9.5 6.9 4.3 8.4 12.9 3.2 3.1 3.9 6.9 1.4 3.8 0.7 5.1 4.3 15.2 2.1 5.1 5.3 4.2 3.9 4.7 26.7 1.0 2.2 7.7 1.0 9.4 23.4 13.8 4.5 1.8 3.9 4.9 3.8 0.7 1.6 2.7 0.9 6.9 6.9 4.4 3.1 7.3 3.1 2.6 8.6 10.1 6.6 3.1 10.0 4.0 4.9 0.2 12.9 0.0 6.7 10.6 4.9 4.3 0.3 5.2 2.4 0.2 0.1 0.0 2.3 0.9 2.2 0.0 0.2 6.3 1.7 4.1 6.8 17.0 4.8 0.1 0.2 0.3 7.8 9.9 0.0 0.1 0.7 20.5 2.9 0.0 1.0 0.1 5.8 0.9 0.2 0.2 1.7 2.9 1.1 2.0 3.0 0.0 3.3 4.5 5.4 4.0 2.7 0.6 1.5 0.0 3.9 0.0 0.5 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 3.5 3.6 3.2 4.0 3.1 3.9 5.1 4.3 3.9 4.5 3.8 4.4 2.2 0.0 0.6 2.6 0.5 4.1 3.8 8.9 5.2 0.0 3.0 4.1 6.4 5.7 3.6 14.7 0.0 14.1 0.4 139.2 1.9 15.0 0.6 1.7 3.1 4.5 15.7 0.0 4.0 17.0 10.7 7.0 19.4 2.2 0.0 3.0 3.9 1.5 4.8 0.0 4.9 79.2 0.0 11.3 6.1 0.3 5.6 15.7 1.8 1.0 43.8 0.0 0.0 0.0 3.6 45.1 98.9 12.0 0.3 4.9 133.2 18.5 4.5 0.0 6.6 0.5 7.3 0.4 0.6 3.4 6.5 28.5 0.9 6.4 56.5 4.1 MUC12 MUC11 ENSG00000205277 "Mucin 12, cell surface associated" Q9UKN1 7 100969623-101018949 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 67.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1187.9;Intestinal goblet cells: 132.3;Paneth cells: 550.8;Undifferentiated cells: 265.8" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 13.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA023835 Enhanced NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023835: AB_1854199" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (2.80e-2)" "unprognostic (1.60e-1)" "unprognostic (3.84e-4)" "unprognostic (4.40e-2)" "unprognostic (1.30e-3)" "unprognostic (1.84e-2)" "unprognostic (1.40e-1)" "unprognostic (6.52e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-1)" "unprognostic (3.33e-7)" "unprognostic (8.42e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 49.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 67.9 0.0 0.0 0.1 0.0 0.0 2.6 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 8.2 3.8 13.1 2.2 0.0 0.0 0.1 0.0 2.7 0.0 2.7 1.8 0.0 0.4 1.4 1187.9 0.0 7.9 13.0 17.2 16.6 1.2 47.5 0.0 3.0 2.8 2.2 15.6 9.2 0.6 8.9 1.6 0.7 0.1 1.9 0.0 0.7 132.3 4.1 1.6 16.0 5.7 0.9 4.0 3.6 1.0 0.0 0.0 0.0 0.0 0.3 8.3 550.8 3.4 2.8 9.5 53.1 0.2 15.7 0.0 0.0 2.2 4.4 11.5 3.8 0.1 3.0 0.5 5.7 5.3 265.8 5.3 MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 614.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 853.2;Intestinal goblet cells: 418.5;Paneth cells: 641.9;Proximal enterocytes: 422.5;Undifferentiated cells: 207.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "OE19: 220.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" 0.8 0.8 0.0 62.0 0.0 0.1 0.5 0.0 0.1 0.8 0.0 304.6 614.6 1.5 0.0 0.8 2.8 47.9 0.1 0.0 0.0 17.5 3.7 0.3 0.4 0.2 0.0 0.0 4.5 0.0 0.1 0.0 0.3 2.1 301.3 0.0 0.0 0.8 0.0 0.1 503.8 10.9 0.0 0.1 35.3 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.1 0.0 0.0 7.4 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.1 6.4 13.6 0.0 0.8 0.2 0.1 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.9 0.1 0.0 0.0 1.0 0.0 220.9 1.1 0.0 0.1 2.7 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 3.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.3 25.8 0.8 0.0 0.0 0.0 0.0 853.2 0.0 24.7 0.9 120.0 1.5 0.4 153.8 0.0 0.1 31.4 0.0 0.0 36.7 6.1 8.9 0.0 0.0 0.0 0.0 0.0 0.2 418.5 0.0 0.3 0.0 4.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.8 641.9 0.7 0.0 1.5 422.5 7.7 10.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 1.5 0.0 207.9 1.4 MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "salivary gland: 2621.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 443.2;Distal enterocytes: 158.4;Intestinal goblet cells: 210.1;Undifferentiated cells: 183.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "OE19: 113.9;PC-3: 120.0" "Not detected" "Not detected" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" NA NA 1300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" 0.1 0.7 0.2 2.0 0.1 0.0 1.3 0.0 0.4 229.4 0.0 58.0 0.1 0.3 0.0 101.0 1.1 221.3 0.1 0.0 0.0 0.1 2.4 7.5 0.0 0.1 0.0 0.1 9.8 0.0 0.4 0.0 0.0 0.6 17.1 0.0 2621.9 0.0 0.3 0.4 2.6 0.6 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.2 0.0 113.9 120.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 2.3 0.0 0.0 6.7 0.6 0.0 6.4 4.3 12.4 443.2 64.0 0.0 0.0 0.1 0.0 158.4 0.0 0.9 0.0 1.4 0.8 0.9 24.5 0.0 0.1 0.0 0.1 1.1 12.8 7.2 4.5 0.0 0.0 1.2 0.2 0.0 0.0 210.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 53.4 0.0 1.4 1.3 0.1 0.2 24.5 0.0 0.0 0.0 3.0 0.0 0.5 1.6 0.0 0.1 0.7 0.1 183.1 1.1 MVB12A "FAM125A, FLJ32495" ENSG00000141971 "Multivesicular body subunit 12A" Q96EY5 19 17405722-17433724 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041885, HPA042231" Approved Supported Vesicles NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041885: AB_10964218, HPA042231: AB_10961043" "unprognostic (1.34e-2)" "prognostic favorable (3.26e-4)" "unprognostic (1.48e-1)" "unprognostic (2.35e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (5.96e-3)" "unprognostic (8.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.77e-1)" "unprognostic (9.93e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.33e-2)" 21.3 28.4 10.5 17.3 11.5 18.2 21.4 11.4 12.3 18.6 11.8 16.7 29.1 17.3 7.4 29.5 22.0 18.7 13.1 10.0 10.3 20.2 19.9 15.5 21.7 14.0 11.0 34.0 20.0 22.2 7.4 19.2 11.6 13.7 11.6 1.2 24.2 17.5 14.4 24.7 22.0 11.6 12.3 22.3 20.9 5.2 11.4 24.0 21.2 12.4 19.3 17.0 18.0 13.5 51.2 23.4 12.1 33.9 15.7 28.8 71.1 18.3 28.4 33.8 40.8 20.1 60.5 32.7 52.7 28.2 28.8 25.5 19.5 35.5 9.0 37.6 60.7 9.5 41.8 44.0 50.3 13.0 29.1 28.2 28.5 29.1 18.0 25.5 40.7 29.9 26.8 65.2 15.6 32.2 24.6 26.2 17.0 40.8 63.9 34.7 14.8 53.1 32.4 21.2 25.3 40.7 19.6 30.2 77.6 10.9 40.1 30.9 21.7 31.5 18.4 35.1 20.5 59.3 72.9 35.0 34.1 49.3 38.9 57.4 61.7 42.9 33.0 66.9 31.0 23.3 34.0 32.0 60.5 29.8 28.0 27.5 36.0 38.2 53.4 53.3 57.2 36.2 10.5 11.5 11.4 12.3 10.0 10.3 14.0 11.0 11.6 12.3 11.4 13.5 67.5 9.6 8.2 5.9 16.4 39.0 41.4 65.1 42.1 5.3 53.6 61.8 5.6 48.6 33.5 46.0 6.2 60.7 18.1 85.0 54.8 78.7 13.5 30.1 26.8 47.7 26.5 8.4 2.2 48.4 99.0 38.6 43.3 30.2 21.6 45.7 62.4 28.0 72.3 3.3 3.2 48.5 50.8 44.9 30.8 16.3 43.5 31.2 32.0 11.2 46.7 32.7 19.6 4.0 7.3 63.4 84.1 47.0 23.5 19.0 104.4 61.3 36.4 13.8 6.6 22.8 40.9 11.8 12.3 58.3 43.9 40.6 21.2 44.3 57.1 45.0 MVP "LRP, VAULT1" ENSG00000013364 "Major vault protein" Q14764 16 29820394-29848039 "Cancer-related genes, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" Ribonucleoprotein "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 504.7;Exocrine glandular cells: 310.8;Paneth cells: 338.3;Proximal enterocytes: 514.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 429.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002321, CAB002752, CAB022717, HPA064740" Enhanced Supported Cytosol NA NA 110000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB002752: , CAB022717: , HPA002321: AB_1079277, HPA064740: AB_2685342" "prognostic favorable (4.51e-4)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (8.17e-2)" "unprognostic (3.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.22e-2)" "unprognostic (6.03e-3)" "unprognostic (2.19e-1)" "unprognostic (6.85e-3)" "unprognostic (2.86e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.22e-1)" "unprognostic (5.19e-2)" "unprognostic (5.69e-3)" "unprognostic (2.65e-2)" 84.4 181.7 26.2 96.0 35.7 46.4 71.0 29.9 33.7 76.6 32.5 165.6 154.7 73.1 14.3 75.4 73.3 74.3 64.4 26.0 31.9 113.4 66.9 121.9 71.1 43.1 36.4 103.3 101.9 18.9 47.5 38.0 35.5 59.7 96.5 6.3 77.1 38.9 50.6 61.1 158.9 69.0 32.6 114.0 107.8 39.4 42.3 31.3 60.6 32.4 47.6 80.0 72.9 38.3 64.8 191.8 0.8 1.7 212.0 275.0 25.9 163.4 258.5 88.0 121.4 24.7 216.8 3.1 134.9 231.0 108.9 78.1 0.8 129.5 42.2 166.4 1.8 3.0 81.6 87.6 190.1 2.3 60.2 366.9 96.1 207.0 58.3 170.5 274.5 6.2 0.5 92.1 167.7 18.3 0.8 4.3 2.4 93.4 11.6 2.1 0.7 32.5 229.1 114.6 10.5 7.6 41.8 53.8 31.8 6.5 9.5 18.7 429.3 124.2 59.4 119.9 62.0 66.6 45.1 2.7 294.6 4.8 24.9 50.4 140.8 56.3 70.9 214.3 55.1 36.6 80.7 73.6 113.1 27.2 59.4 54.0 160.0 73.7 204.0 69.2 90.7 164.4 26.2 35.7 29.9 33.7 26.0 31.9 43.1 36.4 35.5 32.6 42.3 38.3 34.2 48.1 115.5 9.8 31.2 19.6 39.3 120.3 16.5 4.8 17.9 10.0 12.9 82.9 112.0 69.9 2.1 113.6 31.2 504.7 45.0 272.7 4.9 43.9 25.9 40.9 56.5 8.6 3.2 310.8 71.4 52.8 120.8 65.9 33.7 14.8 36.4 23.8 78.0 8.4 3.4 177.1 95.6 41.0 27.1 21.1 57.5 55.0 32.0 9.4 223.3 3.0 59.8 0.0 23.1 278.5 338.3 47.8 36.4 25.0 514.8 194.8 110.3 4.9 19.7 23.8 51.3 2.7 1.8 20.7 21.9 264.5 45.1 24.7 206.8 56.7 MXD1 "bHLHc58, MAD, MAD1" ENSG00000059728 "MAX dimerization protein 1" Q05195 2 69897688-69942945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 173.4;esophagus: 130.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 507.0;Langerhans cells: 224.8;Paneth cells: 369.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 496.3" "Lineage enriched" "Detected in all" 49 "granulocytes: 496.3" "Cell line enhanced" "Detected in many" "hTERT-HME1: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001599 Enhanced Uncertain Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" Cytosol "HPA001599: AB_1079434" "unprognostic (1.59e-1)" "unprognostic (5.11e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (8.14e-6)" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-3)" "unprognostic (3.39e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (8.50e-4)" "unprognostic (8.72e-2)" "unprognostic (3.24e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (1.56e-3)" "unprognostic (1.77e-2)" 13.5 3.6 6.2 40.4 6.9 173.4 7.0 10.0 15.8 35.2 6.4 30.3 28.8 5.4 1.9 130.0 8.1 9.4 8.3 6.5 7.8 6.8 11.3 36.5 3.9 7.1 6.3 6.1 4.6 6.8 6.7 10.9 8.1 5.5 28.9 15.6 17.4 2.0 6.0 12.8 43.7 9.1 5.4 32.8 16.9 6.3 10.7 13.9 7.5 6.5 15.1 17.4 50.6 10.5 5.0 2.1 3.0 2.2 6.5 3.2 11.2 5.5 3.1 2.6 1.9 6.8 3.8 2.8 2.8 2.1 2.5 17.3 5.8 10.7 2.7 1.6 6.9 5.9 6.6 7.0 21.9 7.3 5.7 3.7 17.8 5.9 27.0 3.2 3.4 2.8 10.4 10.9 1.6 4.0 3.4 14.1 0.8 7.3 3.5 1.6 3.1 7.1 3.4 5.8 9.8 4.1 7.3 9.3 3.9 3.4 1.4 4.1 13.2 3.7 1.0 4.1 5.2 7.5 13.7 1.1 3.8 12.5 1.4 124.0 10.2 105.7 2.3 6.4 2.5 1.1 1.6 1.7 5.2 1.3 1.8 1.9 496.3 2.8 5.5 1.6 1.5 4.5 6.2 6.9 10.0 15.8 6.5 7.8 7.1 6.3 8.1 5.4 10.7 10.5 18.0 38.5 23.7 16.0 25.4 25.7 31.6 61.8 21.6 29.8 51.6 29.3 6.9 10.0 44.7 1.8 54.2 10.1 46.2 507.0 7.9 12.9 17.0 34.3 17.5 12.0 97.5 17.7 23.6 16.5 8.0 17.9 110.1 81.6 27.3 3.0 5.7 6.8 28.6 10.1 20.2 155.5 71.2 56.5 224.8 17.8 4.7 190.8 16.0 11.2 40.7 62.1 18.6 20.1 21.7 70.1 369.6 2.6 33.1 43.3 178.8 6.9 24.2 21.7 0.0 14.7 18.3 19.9 2.7 88.2 56.4 105.9 30.3 5.2 65.9 126.7 MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 264.7;Oligodendrocytes: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 108.2;SK-MEL-30: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: AB_10670588, HPA035320: , HPA056762: AB_2683229" "unprognostic (1.77e-2)" "unprognostic (2.02e-1)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.26e-3)" "prognostic unfavorable (9.17e-4)" "prognostic unfavorable (1.02e-5)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" 34.0 32.7 86.8 13.2 98.0 68.0 45.1 92.9 106.1 38.8 67.0 55.9 24.4 45.6 36.2 52.3 42.4 32.8 63.2 84.9 91.1 39.2 51.1 26.4 13.8 93.9 91.8 81.4 44.7 50.6 22.1 28.5 94.7 41.0 35.0 80.2 80.1 52.1 47.3 47.6 29.6 29.8 89.3 14.8 28.0 23.3 94.9 31.2 54.5 53.2 12.3 34.6 41.2 110.8 18.2 8.3 18.0 39.6 30.7 21.4 7.4 11.1 39.2 7.1 23.1 3.2 33.5 24.6 17.6 20.0 11.3 24.3 23.5 27.8 20.0 13.5 30.9 7.3 15.7 14.5 19.5 14.3 14.4 21.7 96.0 12.4 55.2 108.2 7.1 17.5 26.9 54.9 11.3 12.3 10.1 26.1 7.7 31.0 21.2 6.1 26.0 39.9 22.8 1.6 34.3 52.4 11.1 7.3 167.1 23.3 9.9 42.2 7.7 13.5 21.0 13.6 5.6 44.6 26.1 10.0 34.3 46.1 12.7 1.8 2.7 9.7 2.7 2.3 5.1 3.9 5.1 2.8 1.6 3.6 7.7 1.9 5.6 1.4 5.0 1.7 4.8 2.0 86.8 98.0 92.9 106.1 84.9 91.1 93.9 91.8 94.7 89.3 94.9 110.8 28.9 16.0 16.8 139.1 27.9 58.0 57.9 22.8 51.2 49.9 67.2 66.8 80.2 41.5 27.6 33.1 47.9 5.4 23.0 160.7 46.9 19.3 5.1 29.1 36.4 34.1 16.9 264.7 60.8 14.8 20.1 36.0 15.8 37.3 3.8 19.1 27.8 56.6 11.1 52.2 102.5 20.1 18.3 24.1 20.5 8.8 45.1 22.6 104.9 30.9 29.9 144.2 9.2 131.7 214.9 10.4 52.5 55.7 22.5 73.4 57.0 67.1 25.3 46.0 46.0 69.6 63.0 23.8 28.2 37.4 67.3 9.7 36.9 27.4 16.6 36.9 MYB c-myb ENSG00000118513 "MYB proto-oncogene, transcription factor" P10242 6 135181308-135219173 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 35.2;breast: 20.1;intestine: 26.5;lymphoid tissue: 66.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 47.8;Erythroid cells: 83.2;granulocytes: 26.0;Intestinal goblet cells: 32.7;Ionocytes: 26.4;Respiratory ciliated cells: 37.2;Undifferentiated cells: 52.0" "Group enriched" "Detected in many" 5 "breast cancer: 17.7;colorectal cancer: 16.4;stomach cancer: 5.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 4.6;eosinophil: 5.4;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 5.4" "Cell line enhanced" "Detected in many" "HL-60: 219.8;MOLT-4: 403.1;NB-4: 208.5;REH: 244.9;THP-1: 343.8;U-937: 186.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017704, HPA071605" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB017704: , HPA071605: " "unprognostic (1.69e-1)" "unprognostic (5.82e-2)" "unprognostic (1.82e-3)" "unprognostic (1.37e-2)" "unprognostic (4.06e-1)" "unprognostic (8.35e-3)" "unprognostic (1.13e-3)" "unprognostic (2.48e-2)" "unprognostic (6.44e-2)" "unprognostic (1.00e-1)" "unprognostic (3.71e-2)" "prognostic favorable (9.65e-4)" "unprognostic (2.41e-11)" "prognostic favorable (9.87e-4)" "unprognostic (8.35e-2)" "unprognostic (3.04e-2)" "unprognostic (9.40e-2)" 0.3 0.5 1.6 5.3 1.7 35.2 20.1 0.0 0.7 1.6 0.4 25.3 10.9 1.0 0.1 3.0 8.4 0.9 0.1 0.3 0.2 0.1 0.4 2.0 6.3 0.9 1.0 0.0 0.3 3.6 0.0 0.4 0.6 1.4 26.5 0.3 0.6 0.9 0.1 3.0 9.4 1.4 0.2 1.2 2.0 0.7 0.3 66.1 0.1 0.0 7.0 1.1 1.3 0.1 1.8 0.3 1.9 3.0 0.0 0.1 0.3 1.0 0.6 1.1 1.1 0.3 1.4 10.9 0.4 0.3 0.4 0.9 5.6 0.0 0.7 18.0 2.5 138.8 1.0 0.5 0.1 219.8 105.1 0.0 0.1 0.6 0.0 0.5 0.3 133.4 114.6 20.1 1.1 11.6 403.1 208.5 1.5 19.2 1.7 244.9 5.9 33.2 0.3 1.5 10.5 6.9 0.5 10.4 0.6 0.5 7.9 343.8 0.4 0.3 1.6 7.9 2.4 27.7 7.7 66.0 0.1 186.1 2.3 4.6 0.7 5.4 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.4 0.2 1.6 1.7 0.0 0.7 0.3 0.2 0.9 1.0 0.6 0.2 0.3 0.1 0.2 0.0 1.3 0.0 2.3 2.7 1.3 1.3 0.6 0.9 47.8 12.6 0.4 2.8 7.1 0.0 0.0 1.4 9.1 18.1 0.0 0.0 0.1 24.3 0.3 0.3 17.6 83.2 0.6 0.8 0.4 0.5 4.6 2.2 26.0 0.4 0.0 0.0 1.1 0.0 2.7 32.7 26.4 1.2 1.7 0.2 0.0 2.1 8.8 0.0 2.8 0.9 0.0 0.0 0.2 0.1 10.2 0.0 4.6 2.1 2.3 0.0 37.2 0.0 0.0 0.6 0.9 0.0 1.8 10.2 7.0 0.3 3.6 0.1 52.0 2.2 MYH14 "DFNA4, FLJ13881, KIAA2034, MHC16, MYH17" ENSG00000105357 "Myosin heavy chain 14" Q7Z406 19 50188186-50310542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 191.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 487.2;Paneth cells: 306.4;Proximal enterocytes: 376.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 48.6;CAPAN-2: 59.4;HaCaT: 119.0;MCF7: 59.0;OE19: 61.7;RT4: 147.8;SK-BR-3: 51.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062391, HPA067889, HPA070260" Enhanced Approved Nucleoplasm NA NA 9600000 "Cluster 80: Striated muscle - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA062391: AB_2684748, HPA067889: AB_2685917, HPA070260: AB_2686243" "unprognostic (2.52e-1)" "unprognostic (5.81e-2)" "unprognostic (9.63e-2)" "unprognostic (3.73e-3)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.71e-1)" "unprognostic (3.48e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "prognostic favorable (3.97e-8)" "prognostic favorable (7.83e-4)" "unprognostic (8.50e-2)" "unprognostic (3.12e-1)" "unprognostic (2.77e-1)" 12.6 1.0 24.1 7.0 35.0 0.0 8.8 38.2 23.3 13.3 22.0 64.5 83.8 1.5 0.2 63.7 15.4 3.6 41.3 20.0 30.9 10.2 25.4 24.4 0.1 38.7 35.6 0.4 17.3 16.7 18.5 0.4 35.7 8.8 19.5 5.1 44.0 5.7 191.3 87.7 76.7 1.3 29.5 0.1 45.5 2.6 34.4 1.5 33.2 35.1 6.1 11.0 31.8 37.4 48.6 5.0 0.0 25.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 33.1 59.4 0.2 30.1 0.0 3.7 119.0 0.1 0.0 0.0 0.1 8.7 0.0 0.0 25.7 0.0 0.0 17.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 59.0 0.0 0.3 0.8 61.7 0.7 0.1 29.4 0.7 0.0 147.8 0.1 0.2 2.9 51.8 0.0 0.2 9.7 1.9 0.0 0.1 11.7 0.2 0.1 0.9 11.2 0.3 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 35.0 38.2 23.3 20.0 30.9 38.7 35.6 35.7 29.5 34.4 37.4 0.1 80.1 36.5 23.5 2.8 3.3 18.7 29.3 0.0 3.7 17.9 9.3 21.8 44.3 50.9 57.0 2.1 0.1 0.3 487.2 0.0 53.2 0.9 58.1 6.0 1.2 51.6 0.0 10.9 27.2 0.1 1.1 85.1 70.7 14.7 0.0 2.9 45.8 0.1 16.8 21.7 109.4 22.4 0.8 1.6 0.8 0.3 1.3 5.4 2.8 0.0 19.7 0.0 23.6 27.5 67.5 306.4 0.0 0.3 30.8 376.1 7.6 80.6 11.5 0.0 17.7 3.5 0.5 4.6 30.8 21.0 0.0 2.0 0.0 122.8 86.2 MYO15B MYO15BP ENSG00000266714 "Myosin XVB" Q96JP2 17 75588058-75626849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 179.2" "Group enriched" "Detected in many" 4 "Distal enterocytes: 275.4;Paneth cells: 294.2;Proximal enterocytes: 127.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 46.4;HEL: 17.7;HMC-1: 24.9;THP-1: 37.7" "Not detected" "Not detected" "HPA022857, HPA023105" Approved Cytosol No No "Cluster 34: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA022857: AB_1848813, HPA023105: AB_1859526" "prognostic favorable (9.34e-4)" "unprognostic (7.55e-2)" "unprognostic (6.99e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (5.59e-4)" "unprognostic (7.29e-3)" "unprognostic (1.48e-1)" "unprognostic (4.97e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-3)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "unprognostic (3.35e-1)" "prognostic favorable (6.90e-5)" 40.0 17.3 34.7 17.3 39.2 57.0 38.1 33.7 45.1 74.7 29.6 53.6 179.2 46.1 7.5 18.6 65.6 25.8 44.4 32.0 34.0 76.0 29.8 55.1 19.2 39.9 36.8 87.1 20.5 4.7 28.9 15.0 40.1 56.5 21.5 9.9 23.6 14.0 13.2 15.9 149.0 9.8 35.5 108.2 25.7 20.9 36.7 17.7 65.8 8.0 7.2 29.0 44.0 46.1 0.6 46.4 0.3 1.2 0.3 0.1 0.7 0.0 0.0 0.0 0.0 5.8 13.6 0.1 1.5 0.0 0.6 0.5 0.0 0.0 0.0 0.6 2.8 17.7 9.5 11.6 1.3 0.0 24.9 0.8 0.8 0.0 0.1 0.8 0.3 7.3 1.2 5.1 0.0 5.0 0.4 7.8 0.7 12.3 11.2 12.7 0.3 2.1 0.3 1.0 1.3 3.2 0.3 0.5 1.5 1.4 3.5 37.7 0.1 0.3 1.2 0.2 0.0 1.7 0.2 0.2 0.7 8.9 0.6 1.3 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.3 0.0 0.4 0.2 0.0 0.1 34.7 39.2 33.7 45.1 32.0 34.0 39.9 36.8 40.1 35.5 36.7 46.1 13.7 0.0 3.3 44.7 8.4 2.4 2.4 2.0 8.0 4.5 4.0 2.7 7.5 11.5 2.4 9.2 16.7 0.1 11.9 275.4 1.9 1.6 0.7 11.6 8.9 14.6 31.7 9.2 1.1 1.5 0.1 7.1 52.0 8.1 14.0 13.6 21.0 2.1 5.5 1.7 1.4 40.3 12.2 10.0 12.6 2.7 5.6 17.5 3.6 42.2 6.9 4.9 12.3 32.6 46.6 8.8 294.2 4.9 1.4 1.9 127.5 14.4 8.0 13.5 6.6 7.1 8.4 3.3 6.8 2.2 3.0 0.1 6.2 4.7 20.1 1.8 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 3800000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: AB_2667469" "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 169.3 27.0 12.4 34.4 11.8 4.9 115.9 13.3 12.7 77.4 17.1 104.9 47.4 97.1 21.5 64.7 66.4 46.1 97.5 10.2 14.7 56.8 39.5 87.2 24.1 14.8 11.2 43.6 69.3 34.3 22.9 56.9 14.6 69.9 41.7 2.1 91.7 58.2 49.5 57.7 65.6 65.7 11.9 30.8 76.3 17.1 13.7 21.3 60.6 35.8 25.1 86.3 67.8 10.8 169.8 182.1 19.3 79.5 88.8 87.6 74.2 168.6 138.9 108.7 91.0 122.3 90.7 16.9 118.7 261.1 72.7 139.9 29.2 117.2 56.3 75.2 74.5 16.2 96.4 46.2 131.7 1.6 81.5 68.7 57.3 100.2 57.3 99.5 141.7 10.5 13.1 13.7 93.5 129.5 1.9 1.4 12.4 105.8 34.0 6.9 26.4 30.7 100.5 86.9 7.8 43.0 105.9 152.6 67.4 47.5 125.3 8.7 187.9 156.6 119.1 77.7 147.8 10.7 9.1 7.2 124.7 4.1 138.8 0.1 0.9 0.0 0.9 2.0 0.4 4.8 2.1 0.9 1.1 3.8 0.7 0.4 0.5 0.0 1.7 1.0 1.9 1.5 12.4 11.8 13.3 12.7 10.2 14.7 14.8 11.2 14.6 11.9 13.7 10.8 133.7 125.0 35.9 5.5 20.8 39.8 38.2 27.8 31.9 4.1 44.0 33.0 75.4 48.6 36.3 86.5 0.0 57.8 2.5 159.0 21.5 62.3 17.4 26.3 44.4 78.0 39.5 13.5 2.5 52.0 28.4 51.8 66.3 75.5 12.0 25.4 83.6 38.5 20.0 5.0 3.8 111.8 14.2 14.5 43.4 11.4 42.3 16.7 64.0 15.0 20.3 5.6 0.0 2.5 1.0 92.8 88.7 48.5 12.8 64.7 92.8 15.4 12.9 2.1 118.3 37.7 90.6 9.4 7.5 39.5 42.6 47.6 10.0 10.6 88.1 39.2 NANS SAS ENSG00000095380 "N-acetylneuraminate synthase" Q9NR45 9 98056732-98083077 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 362.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019223 Approved Enhanced Nucleoplasm No No 410000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA019223: AB_1854298" "unprognostic (2.95e-1)" "unprognostic (5.10e-3)" "unprognostic (2.24e-2)" "prognostic favorable (1.71e-4)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.42e-4)" "unprognostic (2.08e-1)" "unprognostic (7.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (7.36e-2)" "unprognostic (3.62e-3)" "unprognostic (1.79e-1)" 39.4 28.9 16.2 49.3 15.0 67.8 36.5 13.8 18.2 49.9 29.8 133.5 52.2 28.5 33.5 51.4 29.4 34.2 46.3 15.1 17.0 32.8 67.0 45.9 59.5 16.2 17.2 26.2 67.6 20.4 42.5 31.7 18.4 106.4 129.2 8.3 120.0 19.7 34.2 29.2 47.8 29.0 15.1 53.3 76.1 27.2 17.2 18.8 27.3 17.4 60.5 47.5 41.5 17.2 387.9 111.8 32.5 94.5 64.0 68.8 70.5 120.9 93.7 96.3 78.3 134.8 53.6 118.1 57.2 133.3 101.9 134.1 61.0 103.6 80.0 95.7 91.0 70.3 128.4 271.9 176.3 80.3 55.3 58.4 69.1 102.9 116.4 111.8 104.3 57.9 129.9 119.8 71.2 265.0 54.1 114.9 56.2 277.5 143.3 103.4 89.0 121.5 78.2 116.6 65.7 34.4 77.8 414.4 107.2 35.8 137.6 85.3 274.2 74.8 72.5 193.4 125.8 110.7 99.3 45.7 88.4 95.9 59.6 30.9 190.9 29.5 34.9 237.6 53.4 55.6 45.5 36.8 194.7 54.9 48.8 33.7 77.4 38.9 217.0 178.8 58.3 91.4 16.2 15.0 13.8 18.2 15.1 17.0 16.2 17.2 18.4 15.1 17.2 17.2 46.7 28.9 54.9 3.6 57.0 70.1 134.0 183.0 30.7 11.4 61.6 45.5 25.3 42.9 206.3 22.0 18.8 86.7 50.2 234.3 70.5 49.4 42.8 63.4 37.9 63.4 64.9 18.7 6.7 100.7 159.2 50.6 99.4 55.8 43.8 29.5 34.2 33.6 160.0 10.1 7.2 362.7 95.6 67.7 107.6 71.5 32.3 89.8 129.9 6.5 53.1 14.1 14.4 2.0 3.1 70.9 181.0 26.4 141.1 213.6 66.5 68.3 204.5 8.0 13.1 32.9 91.3 10.5 21.9 42.0 61.7 150.8 50.6 44.6 260.1 223.3 NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 24.2;Paneth cells: 32.7;Respiratory ciliated cells: 32.0" "Cancer enriched" "Detected in all" 14 "breast cancer: 47.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB017782, HPA043704" Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB017782: , HPA043704: AB_2678625" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.07e-4)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (8.25e-2)" "unprognostic (5.20e-2)" "unprognostic (6.53e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (9.51e-2)" "unprognostic (6.60e-2)" "unprognostic (7.44e-2)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (8.15e-2)" 3.6 1.5 0.5 5.4 0.7 3.2 5.9 0.8 0.9 6.5 0.8 14.2 11.7 2.4 15.2 2.5 4.4 3.6 1.8 0.5 0.7 5.7 10.4 3.5 6.0 1.2 0.7 2.9 1.8 1.1 1.0 4.1 0.8 7.3 12.8 0.3 1.9 2.9 0.4 2.4 8.9 3.6 0.8 4.1 4.9 1.8 0.8 4.6 2.1 1.5 6.7 4.5 1.3 1.0 22.6 2.7 2.5 3.3 6.3 6.3 5.3 8.0 8.5 8.8 10.2 4.0 4.7 11.0 6.2 5.2 8.1 3.6 4.5 5.4 8.9 10.3 2.3 7.6 3.0 3.0 6.0 3.3 9.7 5.2 6.5 6.0 0.5 2.2 7.9 9.3 6.6 2.9 10.0 4.0 9.8 10.3 2.4 17.8 3.4 4.9 2.5 4.3 9.3 12.6 1.3 1.7 0.3 9.5 5.5 5.2 7.7 9.7 8.5 5.3 3.1 8.0 1.3 2.0 4.0 9.3 4.6 7.5 2.4 5.4 4.6 9.4 3.3 5.3 2.4 4.4 3.4 3.4 6.1 3.9 3.2 3.9 8.2 6.3 5.4 3.5 6.3 2.7 0.5 0.7 0.8 0.9 0.5 0.7 1.2 0.7 0.8 0.8 0.8 1.0 4.6 0.0 3.6 0.7 4.7 0.4 0.8 9.1 1.2 0.0 3.5 1.9 1.6 0.0 11.3 5.5 0.0 5.9 2.3 24.2 1.9 5.7 10.8 3.9 3.2 3.0 3.6 0.8 0.8 6.9 7.7 2.1 3.6 2.8 2.5 1.1 2.2 12.7 7.2 0.0 0.2 10.7 8.2 6.3 2.6 2.2 4.1 5.3 3.6 1.9 4.9 2.5 4.1 0.0 0.5 5.8 32.7 5.7 2.6 2.3 12.7 16.6 32.0 0.0 0.0 0.7 3.4 4.2 0.6 2.2 0.6 10.9 4.1 3.2 8.4 2.5 NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 676.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.1;Leydig cells: 386.8;Paneth cells: 313.2;Peritubular cells: 356.9;Prostatic glandular cells: 293.3;Proximal enterocytes: 413.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 431.7;HSkMC: 305.6;SK-MEL-30: 473.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" NA NA 8100000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" 166.3 27.7 116.1 61.4 115.2 5.7 183.3 90.6 156.0 676.6 125.7 259.3 195.0 253.9 48.3 206.8 281.5 202.6 119.1 147.1 117.1 67.2 5.8 312.0 57.3 101.7 140.7 635.9 27.1 48.3 125.3 21.6 117.0 376.0 109.3 14.5 65.4 113.5 26.6 199.1 314.1 113.0 95.0 25.8 139.9 44.5 109.5 25.3 85.9 28.4 22.4 246.5 373.8 97.3 138.8 42.9 7.2 38.5 431.7 222.7 19.7 195.5 238.6 64.1 64.7 11.8 242.6 0.2 122.2 245.7 44.8 153.4 40.8 180.1 19.6 132.9 23.0 6.8 40.5 72.4 69.4 0.5 3.1 305.6 162.0 94.6 57.6 19.1 48.7 8.0 1.4 0.4 20.6 20.4 0.4 11.7 2.9 142.3 65.2 6.4 0.1 4.7 122.5 16.6 3.1 102.2 31.2 1.2 473.8 7.1 160.2 24.3 68.9 62.4 49.7 180.0 30.3 0.9 1.1 0.8 45.4 0.6 19.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.4 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.1 116.1 115.2 90.6 156.0 147.1 117.1 101.7 140.7 117.0 95.0 109.5 97.3 150.4 3.2 2.3 0.0 2.9 174.6 237.3 22.6 107.0 35.5 41.5 32.8 43.5 55.8 11.9 36.8 6.2 1.0 5.1 395.1 3.9 43.0 2.0 15.6 55.7 84.3 54.5 3.4 0.0 7.7 2.6 241.4 39.8 10.1 13.4 80.9 47.8 1.5 54.6 6.7 0.0 244.6 12.2 2.2 76.6 13.1 386.8 6.6 60.5 0.0 5.8 13.4 0.0 0.0 0.0 97.5 313.2 356.9 1.1 293.3 413.8 19.7 24.5 10.2 131.5 14.0 142.9 1.4 7.6 61.4 202.4 1.4 29.6 15.1 220.4 206.5 NBPF1 "FLJ20719, KIAA1693" ENSG00000219481 "NBPF member 1" Q3BBV0 1 16562319-16613562 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 73.8;Distal enterocytes: 66.4;Oligodendrocyte precursor cells: 68.3;Oligodendrocytes: 87.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Microtubules,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Microtubules "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (8.16e-3)" "unprognostic (6.96e-2)" "unprognostic (1.33e-2)" "unprognostic (6.09e-2)" "unprognostic (3.49e-1)" "unprognostic (4.76e-2)" "unprognostic (1.15e-5)" "unprognostic (2.16e-2)" "unprognostic (5.40e-2)" "unprognostic (2.99e-1)" "unprognostic (4.90e-2)" "unprognostic (2.14e-2)" "prognostic favorable (1.06e-4)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.68e-1)" 8.8 32.6 4.0 2.5 5.1 2.0 9.5 5.0 4.3 16.4 2.7 14.9 3.5 10.6 2.5 6.4 10.7 3.3 6.1 3.2 4.5 9.0 8.2 6.2 1.3 5.3 4.8 18.1 7.4 6.0 9.0 4.6 5.1 9.9 5.3 2.9 9.3 4.2 5.5 7.2 13.6 5.7 4.6 8.2 8.8 23.0 5.0 1.7 7.2 2.6 1.8 13.6 11.0 6.0 6.1 8.6 8.4 5.1 2.3 2.7 1.5 4.1 5.4 7.7 6.8 3.1 2.4 4.8 1.2 11.7 3.0 5.5 3.9 2.5 8.9 3.0 4.5 1.5 3.0 3.0 3.7 2.4 3.6 2.9 3.1 11.1 3.2 4.0 3.5 10.9 5.2 2.6 3.0 4.7 10.5 1.8 1.6 1.1 16.3 8.9 4.6 0.5 2.2 1.2 10.4 10.3 10.6 4.3 5.8 2.4 6.6 1.7 4.1 6.7 3.6 9.2 3.6 1.3 6.7 2.7 1.5 3.5 2.8 0.1 0.1 1.3 0.3 0.2 0.4 0.3 0.3 0.4 0.1 0.5 0.3 0.4 0.0 0.1 0.3 0.2 0.0 0.1 4.0 5.1 5.0 4.3 3.2 4.5 5.3 4.8 5.1 4.6 5.0 6.0 5.2 16.0 14.8 73.8 5.7 8.2 3.0 10.9 29.0 7.5 8.4 8.6 14.5 8.6 11.6 11.0 8.4 6.3 3.5 66.4 3.9 5.5 10.4 4.4 8.2 10.2 3.0 5.9 33.6 3.5 7.9 19.7 12.2 3.1 6.3 17.1 3.6 6.1 12.8 10.1 52.1 25.4 12.2 6.6 15.9 6.9 6.8 7.1 8.8 47.8 4.4 5.0 9.2 68.3 87.9 6.1 19.3 7.2 5.3 3.8 24.0 10.8 15.5 6.5 6.6 7.9 10.0 52.5 24.3 14.7 7.7 3.1 4.0 43.2 15.2 3.1 NCLN "NET59, NICALIN" ENSG00000125912 Nicalin Q969V3 19 3185563-3209575 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006625 Approved Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "HPA006625: AB_1079453" "unprognostic (4.32e-2)" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "prognostic favorable (1.19e-4)" "unprognostic (8.55e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (9.38e-2)" "unprognostic (2.02e-2)" "unprognostic (1.26e-3)" "prognostic unfavorable (8.37e-5)" "prognostic favorable (8.82e-5)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" 25.8 62.4 19.7 16.2 18.5 33.3 22.3 18.6 25.2 23.1 13.9 36.5 31.1 25.9 4.3 31.0 23.4 6.9 28.0 22.2 15.7 29.5 59.8 33.1 12.7 20.4 18.8 22.0 53.6 11.0 23.5 7.5 18.6 28.9 8.7 3.5 22.9 8.0 29.2 25.8 35.8 8.6 17.4 42.8 29.7 21.8 21.1 8.6 24.4 10.5 6.6 26.3 21.7 17.5 70.8 74.2 21.6 60.3 20.3 15.4 55.4 84.5 33.2 57.5 45.5 103.6 36.8 43.3 67.0 49.4 37.8 87.2 24.7 57.1 12.7 57.4 61.3 31.7 46.2 73.2 41.1 56.8 51.3 29.0 36.2 46.4 24.7 15.2 31.7 41.7 84.1 41.4 25.6 59.3 48.9 64.1 59.3 43.2 63.6 77.8 23.2 71.9 36.5 42.6 45.3 47.1 31.1 56.2 50.3 10.3 38.3 61.9 47.6 45.4 45.8 77.3 100.4 59.0 58.1 36.0 51.1 71.5 72.7 1.4 13.4 9.8 7.1 13.1 5.8 5.4 4.3 7.9 9.2 4.5 4.6 6.2 7.6 4.8 5.6 18.8 4.2 9.6 19.7 18.5 18.6 25.2 22.2 15.7 20.4 18.8 18.6 17.4 21.1 17.5 15.3 16.0 14.7 12.1 19.8 8.3 9.4 18.2 5.7 15.1 15.6 11.9 10.2 15.7 14.8 11.0 10.4 20.4 26.0 71.0 3.9 31.0 15.0 11.3 15.6 14.3 12.6 12.4 13.6 37.4 49.3 14.9 30.5 17.4 15.9 31.1 12.8 43.8 39.3 23.5 14.6 41.2 14.2 18.8 9.2 49.1 9.3 18.1 14.2 8.4 19.2 5.8 14.4 9.0 10.3 35.8 45.3 9.1 51.7 22.0 75.7 11.7 10.5 13.2 13.1 11.8 16.9 13.6 20.1 12.4 12.5 17.0 12.0 115.1 72.7 14.2 NDUFB7 "B18, CI-B18, MGC2480" ENSG00000099795 "NADH:ubiquinone oxidoreductase subunit B7" P17568 19 14566078-14572066 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002817 Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002817: AB_1079462" "unprognostic (2.80e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.03e-1)" "unprognostic (4.09e-2)" "unprognostic (4.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.95e-1)" "unprognostic (1.45e-3)" "unprognostic (2.07e-1)" "unprognostic (1.87e-2)" "unprognostic (2.02e-2)" "unprognostic (4.14e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.40e-1)" "unprognostic (1.69e-1)" "unprognostic (1.59e-1)" "unprognostic (9.25e-3)" 203.1 216.1 209.9 66.1 218.4 103.7 188.8 232.4 325.4 153.6 216.5 256.3 124.6 169.4 51.1 230.7 152.3 57.7 695.8 204.8 222.5 291.7 335.7 127.8 70.4 222.2 221.3 137.3 213.5 143.2 182.8 61.6 218.9 171.0 55.9 28.6 198.7 93.2 709.4 189.4 163.2 50.6 213.2 150.0 231.9 132.8 230.2 50.6 189.7 266.9 39.5 167.3 161.2 222.6 242.1 237.4 95.0 203.1 80.4 80.5 167.4 110.1 120.6 200.0 189.2 317.9 130.2 109.4 322.0 102.9 87.5 185.0 62.6 241.1 26.7 170.1 320.8 212.2 380.9 334.6 142.1 138.7 141.5 131.7 196.6 105.7 49.6 56.1 161.7 194.9 132.9 194.8 94.2 452.7 227.0 308.0 242.4 228.1 773.2 174.3 112.8 264.6 143.0 253.3 204.4 217.6 114.9 265.6 303.4 24.6 175.0 245.1 122.0 253.5 123.2 324.4 207.0 264.4 295.5 144.1 243.7 267.8 174.5 355.6 414.5 140.4 432.9 395.5 403.8 368.6 291.4 368.9 415.4 327.7 241.3 315.5 119.4 422.4 389.5 460.4 373.3 562.3 209.9 218.4 232.4 325.4 204.8 222.5 222.2 221.3 218.9 213.2 230.2 222.6 196.4 76.9 95.9 19.9 155.6 133.4 177.9 358.5 126.9 117.4 285.4 363.9 670.4 245.9 214.2 259.3 56.3 359.7 155.5 937.3 1154.3 324.9 81.8 162.8 133.9 163.5 332.1 152.9 7.4 455.3 330.5 185.2 194.7 152.1 102.2 197.4 203.1 589.1 377.5 72.3 11.4 639.3 299.1 237.9 158.0 252.0 207.5 173.9 378.8 10.3 327.3 236.4 365.6 8.5 25.5 367.9 720.8 200.1 197.5 175.4 916.4 1041.9 193.1 152.4 236.7 193.6 330.8 133.7 252.1 235.7 161.2 225.6 138.6 197.5 631.6 220.1 NET1 "ARHGEF8, NET1A" ENSG00000173848 "Neuroepithelial cell transforming 1" Q7Z628 10 5412557-5459056 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 252.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020068 Uncertain Approved Nucleoplasm,Vesicles Yes Yes "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA020068: AB_2670348" "unprognostic (1.77e-2)" "unprognostic (1.87e-1)" "unprognostic (3.40e-1)" "unprognostic (4.05e-2)" "unprognostic (3.37e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (6.31e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (8.27e-4)" "unprognostic (2.26e-1)" "unprognostic (5.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.46e-1)" 48.8 10.8 35.5 23.4 34.2 40.5 52.8 38.5 57.6 43.7 52.8 92.2 56.2 41.8 56.2 68.4 46.2 35.9 13.2 30.2 32.4 49.3 45.1 22.2 26.7 41.8 37.2 28.5 37.9 5.4 10.6 65.7 43.8 41.3 88.2 6.5 93.1 24.3 25.0 39.8 74.7 36.9 37.5 8.1 77.8 14.4 41.1 30.4 26.2 28.0 33.0 60.8 59.3 40.1 115.9 67.7 45.2 51.0 26.8 11.9 252.9 69.1 37.6 53.4 50.4 36.4 215.2 40.6 27.7 42.4 11.4 185.5 54.9 104.3 63.9 38.1 38.5 77.5 22.9 84.0 7.2 21.5 31.1 18.2 61.0 54.0 12.3 47.6 31.1 42.6 138.5 64.4 30.0 54.3 74.3 30.6 61.5 158.6 51.0 45.0 85.0 32.4 33.4 57.6 38.5 20.6 60.7 110.9 20.3 76.2 36.7 65.3 29.5 20.3 30.9 30.7 56.0 39.3 23.1 53.4 18.1 33.1 43.4 2.0 0.6 1.4 0.6 1.0 0.0 1.4 1.2 0.4 4.9 0.6 8.7 1.7 0.1 0.8 0.4 2.0 4.0 2.2 35.5 34.2 38.5 57.6 30.2 32.4 41.8 37.2 43.8 37.5 41.1 40.1 18.4 32.1 55.8 2.6 12.7 40.3 127.2 49.0 103.0 11.0 52.6 28.3 12.1 41.5 84.3 12.9 4.2 110.2 8.4 242.2 5.9 13.1 2.4 97.7 30.6 42.7 80.8 54.1 5.1 24.4 109.1 33.2 107.0 131.4 15.2 16.9 12.5 55.7 14.5 3.3 7.7 145.3 34.6 10.5 59.8 2.4 21.8 31.2 35.6 44.0 48.7 3.8 0.0 8.5 5.7 62.1 148.3 87.6 39.2 67.8 123.6 29.2 85.7 3.5 111.7 183.0 185.0 26.3 16.0 158.1 32.4 117.5 9.3 2.9 145.0 186.5 NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241809065-241817413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 75.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 74.6;Enteroendocrine cells: 34.4;Hepatocytes: 124.4;Intestinal goblet cells: 38.5;Oligodendrocyte precursor cells: 50.3;Paneth cells: 58.0;Proximal enterocytes: 76.0;Undifferentiated cells: 38.4" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "Hep G2: 57.7;HMC-1: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037394 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA037394: AB_2675455" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" 0.9 0.2 2.3 0.1 2.5 3.5 0.2 2.2 4.4 0.5 0.6 15.5 10.7 0.2 0.0 0.0 0.7 0.4 0.3 2.1 2.5 1.8 75.8 0.4 0.0 5.0 2.8 0.3 0.1 0.0 1.1 0.0 2.7 0.4 2.2 0.1 0.8 0.0 9.0 0.1 9.2 0.0 2.6 0.3 0.1 0.7 2.7 0.0 0.3 0.8 0.0 0.1 0.1 2.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 57.7 0.0 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.5 2.2 4.4 2.1 2.5 5.0 2.8 2.7 2.6 2.7 2.9 0.2 0.0 0.0 1.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.1 0.6 1.5 0.7 1.8 0.0 0.0 1.1 74.6 3.9 0.0 0.1 0.0 0.1 0.3 34.4 0.0 0.4 0.0 0.0 0.2 0.5 0.0 1.3 0.1 1.1 124.4 1.5 0.0 0.4 38.5 2.0 4.2 0.7 0.2 0.6 4.0 0.0 0.0 0.0 26.2 0.0 50.3 0.1 0.0 58.0 0.7 0.4 0.0 76.0 23.6 0.2 1.3 0.0 3.6 0.4 0.5 0.5 0.0 0.0 0.0 1.3 0.0 38.4 0.1 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 82.8;Distal enterocytes: 82.5;Endothelial cells: 53.8;Leydig cells: 54.7;Paneth cells: 42.1;Proximal enterocytes: 53.4;Smooth muscle cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 43.7;T-47d: 20.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 46: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 25.0 16.0 8.4 5.2 10.3 2.0 21.1 2.3 24.1 18.3 3.4 28.4 6.9 24.7 24.1 13.5 22.0 11.7 32.2 17.1 6.9 11.0 6.0 12.6 3.7 3.5 4.6 14.7 5.3 3.2 8.2 6.1 3.8 17.6 13.7 0.3 6.6 32.1 14.0 18.1 17.6 20.4 3.6 0.7 7.7 4.3 6.3 5.9 10.3 16.0 3.9 25.7 17.3 6.5 7.2 3.7 2.0 8.9 0.6 0.3 0.1 8.0 3.5 4.1 6.0 13.7 3.2 0.0 2.1 5.2 5.0 2.1 0.7 3.6 2.8 13.2 0.5 9.8 13.3 0.1 0.6 0.0 2.9 0.0 15.1 0.9 4.1 1.2 0.6 1.4 0.0 3.0 8.9 8.0 2.3 0.2 1.3 3.1 0.3 43.7 9.4 1.4 0.1 1.6 1.6 8.9 7.6 11.9 0.3 3.5 20.0 1.5 1.3 3.1 18.1 2.2 5.1 1.2 0.4 0.0 9.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.3 2.3 24.1 17.1 6.9 3.5 4.6 3.8 3.6 6.3 6.5 82.8 0.0 1.9 0.3 0.6 4.8 0.7 3.0 0.6 0.6 1.5 1.3 9.3 1.5 4.8 0.0 0.0 0.3 0.4 82.5 0.0 0.7 2.6 1.9 2.5 53.8 13.9 11.4 5.2 0.7 0.2 10.3 2.0 0.6 0.0 4.9 30.4 0.3 0.3 0.0 1.0 10.2 2.0 1.9 2.6 6.6 54.7 2.2 7.2 4.7 0.7 0.7 0.0 5.0 13.0 4.5 42.1 12.4 0.1 1.9 53.4 0.8 12.8 0.3 26.3 11.6 58.8 2.5 3.4 7.7 5.4 0.1 0.7 2.5 20.0 1.2 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722205-65871725 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.8;Excitatory neurons: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.6;intermediate monocyte: 3.4;myeloid DC: 2.2;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.2;monocytes: 3.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 64000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favorable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 2.2 1.0 3.8 2.4 3.9 1.5 3.7 2.9 5.3 1.8 1.6 3.6 1.1 2.7 2.4 2.5 1.5 1.2 2.6 3.8 3.6 3.9 9.9 1.7 1.7 3.9 3.4 1.8 2.5 1.5 0.9 2.4 4.0 2.6 3.2 2.5 1.9 1.1 8.9 2.8 2.7 2.7 3.3 1.3 4.0 1.1 3.9 0.9 2.7 6.5 2.0 2.7 1.5 4.8 13.3 12.5 7.2 12.0 9.0 15.3 14.5 13.1 5.5 7.6 8.2 7.2 7.7 18.8 16.1 15.8 15.1 10.3 9.5 20.2 13.1 5.6 6.4 5.2 8.7 18.5 7.7 12.0 3.0 11.7 10.8 10.5 12.4 6.3 21.7 8.3 11.4 3.9 16.5 10.2 8.3 10.8 22.2 6.7 3.6 9.6 15.3 29.9 12.6 5.9 22.3 11.5 10.6 10.7 11.0 19.4 12.9 14.1 12.5 5.0 5.9 7.4 10.0 3.3 7.1 8.2 7.7 23.2 7.7 0.1 2.6 0.1 0.1 3.4 0.1 0.4 0.2 0.1 2.2 0.4 0.3 0.2 0.3 0.5 2.3 0.1 0.0 1.0 3.8 3.9 2.9 5.3 3.8 3.6 3.9 3.4 4.0 3.3 3.9 4.8 5.9 6.4 2.8 19.6 4.0 5.7 9.0 6.2 8.6 2.4 10.1 8.9 14.5 7.2 8.5 12.9 4.2 5.3 0.6 52.8 5.9 17.8 0.3 7.4 12.9 8.3 1.8 9.0 58.9 14.5 14.0 7.1 20.4 20.9 15.2 16.2 4.6 32.4 28.8 5.0 32.2 5.8 6.1 22.9 8.9 0.4 4.4 13.5 1.8 5.6 17.9 13.1 2.1 22.6 44.5 30.2 35.9 2.2 4.9 16.5 32.3 22.4 3.1 4.7 0.0 19.7 8.1 2.1 5.2 15.3 5.3 2.9 2.3 15.8 8.2 6.1 NMNAT1 "LCA9, NMNAT, PNAT1" ENSG00000173614 "Nicotinamide nucleotide adenylyltransferase 1" Q9HAN9 1 9943428-9985501 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059447 Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA059447: AB_2684022" "unprognostic (1.94e-1)" "unprognostic (3.81e-3)" "unprognostic (7.54e-3)" "unprognostic (1.01e-1)" "unprognostic (3.50e-1)" "unprognostic (1.73e-1)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (4.45e-3)" "unprognostic (4.55e-2)" "unprognostic (1.12e-1)" "unprognostic (3.57e-1)" "prognostic favorable (3.85e-14)" "unprognostic (3.11e-3)" "unprognostic (1.17e-1)" "unprognostic (1.47e-3)" "unprognostic (5.16e-2)" 5.2 7.4 5.4 4.4 6.0 2.5 5.7 4.8 7.7 5.4 9.2 9.0 6.0 3.8 5.8 5.2 4.8 3.4 10.7 5.1 5.2 8.2 7.8 3.2 4.3 5.6 5.4 2.9 4.9 8.2 3.8 3.7 5.5 4.5 9.0 5.3 5.2 5.4 23.3 5.7 6.1 5.0 4.7 5.0 4.4 4.3 5.9 4.2 7.3 16.9 4.6 4.0 3.6 7.2 4.6 5.4 7.5 7.1 13.4 12.2 1.8 9.1 7.2 10.3 6.7 2.4 7.7 4.8 5.7 12.9 4.5 4.6 9.4 12.4 11.0 10.4 4.8 7.6 3.0 7.6 11.4 6.7 7.7 13.3 14.2 12.1 17.4 9.5 10.2 10.4 9.7 3.1 10.9 8.0 3.8 4.4 0.9 10.2 10.2 4.2 4.7 2.7 11.9 2.5 5.4 2.8 11.8 9.7 10.4 3.8 3.5 7.2 10.2 4.1 3.3 8.7 4.2 4.5 4.3 4.5 7.1 13.8 8.6 7.5 3.7 3.2 1.6 2.6 0.8 4.9 1.6 1.9 3.3 2.3 1.4 1.8 9.1 2.5 3.9 3.2 1.5 1.8 5.4 6.0 4.8 7.7 5.1 5.2 5.6 5.4 5.5 4.7 5.9 7.2 5.6 3.2 4.4 10.1 3.7 2.3 5.6 14.3 2.2 7.7 6.1 5.1 14.4 4.3 7.3 7.3 6.2 10.1 3.7 18.8 23.5 9.1 7.8 5.5 8.1 7.9 3.0 2.1 13.0 6.9 4.7 5.7 4.1 6.1 4.5 9.2 7.5 9.0 12.9 10.1 14.3 7.6 12.2 10.3 2.7 3.7 6.5 7.2 5.4 4.7 13.5 9.6 12.3 6.0 13.2 6.0 6.2 6.4 0.9 5.9 19.0 14.3 8.6 7.1 6.6 5.9 5.1 17.3 8.3 3.6 1.8 9.0 3.6 13.1 14.5 4.8 NOP9 C14orf21 ENSG00000196943 "NOP9 nucleolar protein" Q86U38 14 24299850-24309124 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000850 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Cytosol" "HPA000850: AB_1078287" "unprognostic (1.39e-1)" "unprognostic (4.64e-2)" "unprognostic (4.57e-3)" "unprognostic (1.85e-1)" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.69e-2)" "unprognostic (9.37e-2)" "unprognostic (7.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (6.77e-2)" "prognostic favorable (9.39e-6)" "unprognostic (7.03e-3)" "unprognostic (3.80e-1)" "unprognostic (1.95e-1)" "unprognostic (1.59e-2)" 9.9 13.0 6.3 5.5 6.7 7.0 9.3 6.2 6.1 8.6 4.6 11.1 7.8 9.9 3.5 16.1 9.5 3.3 13.2 5.8 6.3 8.6 13.8 8.7 6.2 6.7 6.5 11.7 12.6 6.7 7.9 4.1 6.4 9.0 5.5 7.4 10.6 4.4 27.2 12.6 11.4 4.9 6.9 17.3 10.6 7.7 6.8 5.9 8.6 11.2 6.7 9.8 9.3 6.3 6.5 12.8 10.2 12.8 8.7 7.3 9.8 11.4 8.5 13.2 10.2 9.7 11.3 16.7 6.3 10.5 10.7 16.6 20.4 14.2 13.7 10.6 7.8 12.3 18.3 22.4 7.0 28.4 13.5 7.4 10.9 9.7 8.9 7.0 12.4 9.3 10.6 8.0 9.3 11.3 13.2 10.7 4.6 22.9 16.2 16.0 6.1 10.6 8.1 14.8 10.2 7.8 16.1 18.4 3.5 7.3 6.9 7.4 12.8 8.7 7.2 6.9 10.9 11.1 10.6 12.2 4.8 12.7 7.1 0.3 0.6 0.5 0.4 0.7 0.4 0.3 0.3 0.2 0.5 0.4 0.2 0.2 0.1 0.1 1.2 0.3 0.3 0.4 6.3 6.7 6.2 6.1 5.8 6.3 6.7 6.5 6.4 6.9 6.8 6.3 4.0 3.2 3.3 2.6 6.2 12.5 3.2 4.9 6.2 8.1 5.3 3.9 1.2 7.2 8.5 9.2 8.4 6.3 6.7 15.2 0.0 7.3 3.1 5.2 4.8 5.6 10.7 9.9 3.6 10.3 5.8 4.5 6.1 5.0 1.3 9.6 6.1 18.1 7.3 6.7 4.3 7.6 0.0 10.7 6.3 1.3 6.5 5.8 0.0 1.0 7.6 5.5 2.1 3.0 5.0 11.6 8.5 4.5 5.5 5.2 12.5 6.6 7.7 8.0 6.6 5.4 5.4 4.6 5.7 8.1 13.5 6.4 4.9 5.5 14.3 4.6 NOS2 "HEP-NOS, iNOS, NOS, NOS2A" ENSG00000007171 "Nitric oxide synthase 2" P35228 17 27756766-27800529 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 21.1;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 40.3;Extravillous trophoblasts: 27.7;Granulosa cells: 57.3;Proximal enterocytes: 10.7;Undifferentiated cells: 10.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "CACO-2: 16.5;SCLC-21H: 13.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002014 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB002014: " "unprognostic (1.95e-3)" "unprognostic (3.08e-3)" "unprognostic (4.75e-3)" "unprognostic (4.42e-3)" "unprognostic (3.49e-1)" "unprognostic (2.13e-2)" "unprognostic (5.61e-2)" "unprognostic (5.09e-2)" "unprognostic (9.91e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "unprognostic (1.34e-1)" "unprognostic (6.04e-2)" "unprognostic (8.02e-2)" "unprognostic (3.68e-1)" "unprognostic (8.69e-2)" "unprognostic (4.03e-2)" 0.9 0.5 0.2 14.4 0.5 0.0 0.3 0.1 2.1 0.3 0.0 6.8 12.1 0.2 0.0 0.7 0.4 0.4 0.4 0.7 0.2 1.6 0.1 1.8 0.8 0.3 0.1 0.6 0.3 0.1 1.3 0.6 0.5 0.6 8.9 0.2 0.1 0.2 0.8 0.2 21.1 1.8 0.1 0.1 0.1 0.3 1.0 0.1 0.4 0.7 0.1 3.6 0.2 0.9 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.9 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 2.1 0.7 0.2 0.3 0.1 0.5 0.1 1.0 0.9 1.2 0.0 0.0 1.3 0.6 0.0 0.2 3.6 0.0 0.5 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.2 0.0 40.3 0.0 0.0 0.2 0.0 0.0 0.7 2.4 0.0 4.1 0.0 27.7 0.2 0.0 0.1 0.0 57.3 0.0 0.0 0.7 0.0 2.2 3.8 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 4.9 0.4 0.0 1.4 10.7 0.1 0.5 0.1 0.0 0.3 1.2 0.0 1.5 0.0 0.0 0.5 0.3 0.1 10.2 1.0 NOX1 "GP91-2, MOX1, NOH-1, NOH1" ENSG00000007952 "NADPH oxidase 1" Q9Y5S8 X 100843324-100874359 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "intestine: 71.7" "Group enriched" "Detected in some" 8 "Distal enterocytes: 45.8;Intestinal goblet cells: 21.4;Paneth cells: 29.1;Undifferentiated cells: 64.8" "Cancer enriched" "Detected in many" 18 "colorectal cancer: 82.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "CACO-2: 30.9;OE19: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (8.31e-2)" "unprognostic (2.07e-3)" "prognostic favorable (9.71e-4)" "unprognostic (1.67e-2)" "unprognostic (3.37e-1)" "unprognostic (6.55e-3)" "unprognostic (5.48e-3)" "unprognostic (8.68e-3)" "unprognostic (1.32e-1)" "unprognostic (5.23e-2)" "unprognostic (1.18e-1)" "unprognostic (3.86e-3)" "unprognostic (2.56e-3)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (5.28e-2)" "unprognostic (1.81e-3)" 0.3 0.5 0.0 2.9 0.0 0.0 0.1 0.1 0.1 0.1 0.0 58.9 0.5 0.3 0.0 0.5 0.2 0.7 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.3 71.7 0.3 0.2 2.4 0.1 0.7 1.6 1.6 0.0 0.1 0.1 0.2 0.1 0.3 0.4 0.0 0.0 1.3 0.0 0.0 0.4 1.1 0.4 0.4 0.2 0.0 0.3 0.3 0.0 0.0 0.0 30.9 0.4 0.4 0.7 0.0 0.2 0.7 0.0 0.0 0.0 0.4 1.4 0.5 0.6 0.9 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.3 0.0 0.3 1.3 1.2 0.8 11.6 1.1 0.7 0.7 0.5 0.0 1.1 0.5 0.6 0.7 0.3 0.7 0.3 0.2 1.0 0.3 0.4 0.3 0.5 0.8 0.3 0.7 0.3 0.8 1.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 29.1 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 64.8 0.6 NOXA1 "FLJ25475, NY-CO-31, SDCCAG31" ENSG00000188747 "NADPH oxidase activator 1" Q86UR1 9 137423350-137434406 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 37.5;Gastric mucus-secreting cells: 54.6;Paneth cells: 34.7;Proximal enterocytes: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 12.6;EFO-21: 11.3;MCF7: 19.8;T-47d: 18.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044781 Uncertain Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA044781: AB_10960532" "unprognostic (2.15e-1)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.42e-3)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.79e-1)" "unprognostic (3.99e-3)" "unprognostic (2.72e-1)" "unprognostic (1.69e-1)" "unprognostic (5.45e-3)" "unprognostic (1.97e-3)" "prognostic favorable (2.65e-4)" "unprognostic (4.97e-3)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-2)" 3.7 6.6 11.4 3.5 11.9 3.0 6.9 7.4 24.4 7.5 5.1 12.6 19.3 6.1 1.2 9.6 9.3 6.9 3.9 11.2 10.8 14.7 12.5 4.6 2.5 13.0 11.7 10.1 17.2 6.1 15.4 1.2 9.6 10.4 3.8 2.6 19.9 7.1 10.3 18.4 13.2 1.3 7.7 7.1 17.6 3.9 11.5 2.7 12.9 1.4 1.4 5.6 8.7 8.5 2.0 5.0 0.1 3.8 0.4 0.0 2.6 0.4 0.6 0.2 0.3 0.8 12.6 0.0 11.3 0.1 0.8 8.6 0.2 0.2 0.0 5.5 4.2 0.0 3.6 1.9 1.2 0.1 2.4 0.4 2.7 0.0 0.1 2.2 0.3 0.0 0.7 0.8 0.0 19.8 0.0 1.1 0.2 5.2 1.7 0.1 0.0 7.8 3.3 4.3 1.0 0.3 0.3 2.0 2.0 0.2 18.8 1.6 1.3 0.2 2.6 2.9 0.4 0.8 0.0 0.1 0.3 0.7 0.6 0.0 0.4 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.7 0.1 0.1 0.4 0.0 0.6 2.5 0.0 0.0 0.2 11.4 11.9 7.4 24.4 11.2 10.8 13.0 11.7 9.6 7.7 11.5 8.5 4.0 0.0 5.4 6.5 4.0 3.4 6.1 2.8 3.4 9.8 16.2 11.2 1.3 14.3 7.2 12.9 8.4 0.4 2.3 37.5 7.9 7.4 0.3 11.2 2.1 2.4 6.7 2.7 22.4 11.0 0.4 1.7 54.6 20.0 2.5 3.8 0.7 6.5 5.4 3.3 17.0 20.5 4.1 3.8 9.0 0.5 1.2 6.1 8.8 6.5 3.8 10.7 4.1 8.0 3.8 7.0 34.7 0.7 2.1 4.4 39.5 19.9 5.9 8.2 6.6 3.2 3.8 5.1 5.0 12.8 4.1 0.3 3.5 1.0 24.6 7.4 NOXO1 "P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28" ENSG00000196408 "NADPH oxidase organizer 1" Q8NFA2 16 1978917-1984192 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.6;lymphoid tissue: 4.7;testis: 4.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.1;Intestinal goblet cells: 34.7;Paneth cells: 20.5;Undifferentiated cells: 42.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;HaCaT: 1.6;OE19: 4.3" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA071540 Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA071540: AB_2686415" "unprognostic (3.74e-1)" "unprognostic (1.10e-1)" "unprognostic (1.73e-2)" 0.1 0.2 0.6 4.7 0.8 0.3 0.4 0.5 1.6 0.6 1.0 8.6 3.1 0.3 1.1 0.9 0.2 0.3 0.1 0.6 0.4 0.6 2.3 0.3 0.4 1.1 0.2 0.3 0.4 0.1 0.9 0.0 1.3 0.6 5.9 0.3 2.4 0.2 0.5 0.5 3.4 0.5 0.1 0.3 0.3 4.8 0.5 1.0 0.2 0.0 1.6 0.4 0.3 0.8 0.1 0.4 0.4 0.1 0.2 0.0 0.0 0.0 0.1 0.4 0.2 0.3 2.7 0.2 0.1 0.0 0.0 1.6 0.0 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.4 0.1 0.4 0.1 0.4 0.0 0.6 0.1 0.0 0.0 0.1 1.4 0.0 0.0 4.3 0.0 0.2 0.4 0.0 0.3 0.0 1.4 0.0 0.6 0.5 0.1 0.1 1.0 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.3 0.6 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.5 1.6 0.6 0.4 1.1 0.2 1.3 0.1 0.5 0.8 0.1 0.0 0.0 0.3 0.4 0.3 1.3 9.0 2.8 0.1 7.1 1.8 0.0 1.5 10.6 5.5 0.0 0.8 0.1 52.1 0.0 1.0 6.2 2.9 0.3 0.1 6.6 0.0 1.1 1.9 2.9 0.1 4.6 2.0 0.0 0.2 0.4 0.4 0.3 0.0 0.9 34.7 6.1 0.3 0.3 1.5 0.6 0.1 0.0 0.0 0.6 0.6 0.0 0.0 0.2 1.0 20.5 0.4 0.0 3.3 14.4 1.0 10.6 0.0 0.0 0.0 0.6 3.2 3.3 1.5 0.4 1.5 0.2 0.2 42.4 5.7 NPIPB11 ENSG00000254206 "Nuclear pore complex interacting protein family member B11" E5RHQ5 16 29381354-29404029 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Early spermatids: 17.5;Intestinal goblet cells: 9.4;Undifferentiated cells: 9.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (6.82e-2)" "unprognostic (2.99e-1)" "unprognostic (1.93e-3)" "unprognostic (1.42e-1)" "unprognostic (1.14e-1)" "unprognostic (6.92e-3)" "unprognostic (3.06e-1)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (5.57e-4)" "unprognostic (7.41e-2)" "unprognostic (2.94e-6)" "unprognostic (2.79e-1)" "unprognostic (1.98e-1)" "unprognostic (5.96e-3)" "unprognostic (4.79e-5)" 2.8 1.6 6.0 2.8 5.4 4.7 2.5 7.2 8.4 2.9 6.3 2.7 2.0 2.1 3.2 2.1 3.1 1.8 2.3 5.6 6.7 3.3 4.2 2.5 6.0 5.5 4.6 3.3 2.0 0.9 2.6 1.2 5.4 2.8 1.7 5.8 2.2 0.6 4.4 6.7 3.7 0.9 3.4 4.4 2.7 4.9 5.8 2.0 3.2 0.9 1.1 2.3 2.5 6.6 1.5 1.2 2.2 3.2 1.6 1.2 2.9 1.4 0.6 1.2 0.5 1.7 2.9 9.0 2.1 0.7 0.5 2.6 1.8 2.1 1.2 2.2 2.4 2.1 4.4 2.8 0.8 2.6 4.9 0.7 1.6 1.3 1.8 2.5 0.6 2.4 2.7 2.6 1.1 3.5 2.2 8.3 3.8 0.9 2.7 3.3 0.9 3.0 1.3 1.1 2.9 1.4 0.4 2.0 1.1 6.8 1.1 3.3 3.0 3.0 1.3 2.1 1.9 2.5 1.7 7.3 1.7 3.3 2.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.5 0.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 6.0 5.4 7.2 8.4 5.6 6.7 5.5 4.6 5.4 3.4 5.8 6.6 1.4 9.6 5.6 3.6 4.2 0.0 0.1 0.3 0.6 0.2 1.5 0.9 2.5 1.5 2.6 0.0 0.0 0.3 3.7 8.8 0.0 1.2 17.5 0.6 0.5 2.6 7.2 1.3 4.6 0.8 0.2 1.8 3.6 0.6 5.1 0.4 0.4 0.2 0.3 5.0 5.4 9.4 0.0 0.0 0.0 5.9 0.3 1.6 0.0 1.0 1.5 0.1 5.2 2.5 4.2 1.9 5.9 0.7 2.7 0.1 3.7 0.3 2.3 0.3 0.0 0.5 1.0 0.8 0.1 0.5 0.0 0.4 4.4 0.3 9.8 0.0 NR2F6 "EAR-2, EAR2, ERBAL2" ENSG00000160113 "Nuclear receptor subfamily 2 group F member 6" P10588 19 17231883-17245919 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 206.0;Hepatocytes: 148.4;Horizontal cells: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079917 Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB079917: AB_2635238" "unprognostic (1.48e-1)" "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.07e-1)" "unprognostic (3.67e-1)" "unprognostic (7.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (6.62e-2)" "unprognostic (9.68e-2)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (7.28e-3)" "unprognostic (1.37e-3)" 17.0 21.8 19.3 5.0 16.9 1.2 17.7 15.8 22.8 18.8 23.8 39.4 31.2 19.8 14.3 47.4 19.1 2.9 39.0 16.8 20.2 32.8 104.0 17.5 1.7 23.9 21.4 12.1 44.6 10.4 22.0 13.1 18.6 25.3 9.3 6.6 28.0 9.8 27.9 23.9 25.4 4.5 17.5 9.9 38.6 14.3 20.4 1.8 21.6 9.9 2.7 25.5 22.2 15.6 65.0 38.1 20.3 37.2 7.9 8.8 187.2 35.7 12.9 15.2 13.1 26.1 55.5 15.2 108.8 16.0 8.9 31.9 15.6 20.5 6.7 20.4 90.0 13.9 24.4 47.3 17.3 6.7 18.8 11.6 23.2 7.0 11.3 15.9 9.5 6.8 33.3 3.7 6.7 34.7 5.9 24.7 55.8 48.1 58.5 11.6 12.7 13.2 21.2 41.3 16.3 46.7 19.9 68.7 43.1 19.6 38.2 21.1 15.8 10.7 26.1 20.6 28.8 21.0 7.9 10.9 13.1 9.9 13.4 0.0 0.6 1.1 1.7 0.0 1.4 0.3 2.3 1.5 1.1 2.3 3.8 1.3 0.1 4.6 0.1 0.5 2.4 0.8 19.3 16.9 15.8 22.8 16.8 20.2 23.9 21.4 18.6 17.5 20.4 15.6 21.2 9.6 22.9 6.8 4.7 10.6 14.1 12.8 11.4 71.9 65.9 54.7 36.4 34.3 20.8 25.8 77.2 65.4 3.7 206.0 29.4 23.2 13.3 51.7 32.5 20.8 46.0 4.4 7.2 47.8 65.3 17.6 47.4 60.0 1.3 26.1 15.0 148.4 16.3 151.4 7.6 80.2 24.4 4.7 4.6 6.0 17.7 5.2 10.6 8.4 2.4 45.7 1.0 6.6 5.8 50.4 78.5 18.8 1.2 23.2 72.3 30.2 25.9 54.3 6.6 17.3 24.5 1.6 9.0 24.3 10.5 79.8 4.2 44.3 75.3 18.2 NSMF NELF ENSG00000165802 "NMDA receptor synaptonuclear signaling and neuronal migration factor" Q6X4W1 9 137447570-137459334 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 361.3" "Cell type enhanced" "Detected in many" "Astrocytes: 71.5;Peritubular cells: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 3.5;intermediate monocyte: 13.8;myeloid DC: 6.3;non-classical monocyte: 12.1" "Group enriched" "Detected in many" 5 "dendritic cells: 6.3;granulocytes: 3.5;monocytes: 13.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044316 Supported Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA044316: AB_10964877" "unprognostic (1.48e-1)" "unprognostic (4.03e-2)" "unprognostic (5.40e-2)" "unprognostic (3.92e-2)" "unprognostic (8.54e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (7.96e-2)" "unprognostic (3.26e-2)" "unprognostic (2.38e-3)" "unprognostic (2.34e-3)" "prognostic favorable (1.85e-6)" "unprognostic (1.97e-2)" "unprognostic (4.14e-2)" "unprognostic (4.61e-2)" "unprognostic (3.97e-2)" 23.1 14.5 167.1 12.6 154.3 12.2 20.3 66.6 361.3 24.2 73.4 22.7 29.9 32.8 10.7 16.3 28.7 9.7 16.1 360.8 115.1 30.8 23.5 19.8 13.0 99.7 153.1 22.5 31.6 17.9 70.6 7.1 75.1 31.2 10.4 12.1 20.2 13.8 8.9 20.6 24.9 13.9 109.9 17.0 23.5 18.9 210.5 8.4 23.9 3.9 10.3 22.2 17.5 105.4 24.4 19.3 33.7 50.4 77.1 36.4 28.9 23.0 30.2 21.5 16.5 51.7 14.3 30.2 30.3 34.0 48.1 72.7 50.0 30.9 12.9 39.7 53.8 23.5 46.7 69.5 41.7 16.2 51.5 41.7 57.9 25.1 58.3 48.5 23.1 0.8 55.0 4.9 29.2 56.4 0.7 69.8 42.9 97.6 51.4 14.6 53.3 68.0 14.9 12.1 135.7 112.8 55.0 30.3 35.7 13.9 21.5 33.0 58.6 37.9 30.9 92.9 39.6 10.3 17.0 45.8 21.6 21.2 35.6 1.6 2.1 3.5 1.5 13.8 0.3 0.2 0.5 0.9 6.3 0.1 0.5 0.7 0.3 0.0 12.1 0.2 0.8 1.8 167.1 154.3 66.6 361.3 360.8 115.1 99.7 153.1 75.1 109.9 210.5 105.4 9.9 0.0 3.9 71.5 5.9 13.6 9.4 3.6 7.4 9.6 14.3 12.4 6.1 11.5 2.3 11.0 8.4 0.4 17.7 40.7 5.9 8.2 7.1 7.6 18.3 9.5 19.2 1.7 24.2 21.4 1.3 11.0 10.2 11.1 2.5 12.0 9.7 26.3 6.7 28.6 14.9 21.3 8.2 8.6 21.2 15.3 23.9 10.5 16.0 15.9 9.8 10.3 6.2 16.1 5.3 21.4 34.3 71.5 8.5 32.6 43.4 29.7 2.9 12.9 13.1 8.3 10.9 3.0 5.9 6.3 14.6 1.5 8.0 11.0 20.5 16.7 NT5C "cdN, DNT-1, DNT1, PN-I, UMPH2" ENSG00000125458 "5', 3'-nucleotidase, cytosolic" Q8TCD5 17 75130225-75131757 "Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021581, HPA023632" Approved Supported Cytosol NA NA 760000 "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA021581: AB_1854663, HPA023632: AB_1854662" "unprognostic (3.83e-2)" "unprognostic (4.45e-2)" "unprognostic (2.39e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (9.21e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.26e-1)" "unprognostic (7.25e-2)" "unprognostic (8.26e-3)" "unprognostic (7.15e-2)" "unprognostic (2.22e-1)" "unprognostic (6.57e-2)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "prognostic favorable (7.66e-4)" 31.6 31.4 14.5 17.9 15.9 16.3 31.8 16.5 17.4 37.0 14.8 43.0 24.5 34.7 5.2 45.9 32.1 8.4 32.6 14.1 16.7 47.8 29.1 29.2 18.3 17.1 15.5 37.5 33.7 11.7 18.9 10.2 15.6 35.7 13.1 8.7 25.8 15.3 41.1 33.8 43.7 7.6 16.6 40.7 36.8 15.2 15.5 16.0 37.7 16.1 15.2 37.9 35.9 18.4 52.5 77.7 25.3 26.5 7.5 15.4 33.7 29.5 26.2 29.7 18.8 29.5 58.3 35.5 21.5 21.0 5.2 33.7 18.1 37.7 16.5 16.1 51.3 40.5 68.7 50.0 38.0 38.8 17.2 23.1 17.4 21.3 57.0 11.9 33.0 27.6 38.4 16.8 30.2 51.2 28.0 39.0 26.5 43.6 50.6 24.9 32.9 50.9 39.3 26.7 30.0 60.1 28.3 34.8 43.9 14.0 49.8 27.2 20.4 25.0 62.1 9.8 40.3 33.3 5.6 41.1 23.8 23.3 40.4 183.7 29.7 48.9 39.2 49.6 27.7 94.9 25.5 33.6 37.9 87.4 21.6 33.5 14.4 72.6 50.7 50.4 45.2 30.2 14.5 15.9 16.5 17.4 14.1 16.7 17.1 15.5 15.6 16.6 15.5 18.4 23.0 32.1 19.5 22.2 132.9 47.4 86.1 108.8 90.5 66.0 58.8 101.9 16.4 77.2 35.2 58.8 20.9 64.9 85.8 272.8 78.2 102.2 2.1 53.2 53.5 26.6 64.1 59.5 7.7 121.4 100.4 59.8 181.5 43.2 46.3 59.0 11.7 41.9 74.5 42.1 8.0 133.4 52.9 55.7 64.4 6.8 59.4 56.2 58.7 18.7 108.4 55.9 98.9 19.6 19.2 127.5 221.6 47.4 51.2 115.8 231.6 144.2 31.1 65.5 32.9 39.0 107.6 19.0 49.6 89.4 44.3 31.2 67.4 98.4 152.8 85.9 NUTM2A FAM22A ENSG00000184923 "NUT family member 2A" Q8IVF1 10 87225448-87236908 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 10.2" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies" "HPA064635: " "unprognostic (1.75e-2)" "unprognostic (1.33e-2)" "unprognostic (1.03e-1)" "unprognostic (8.29e-2)" "unprognostic (5.67e-2)" "unprognostic (8.08e-2)" "unprognostic (1.75e-2)" "unprognostic (6.84e-2)" "unprognostic (2.46e-3)" "unprognostic (1.75e-2)" "unprognostic (7.24e-2)" "unprognostic (1.40e-1)" "unprognostic (4.24e-3)" "unprognostic (1.35e-1)" "unprognostic (1.11e-1)" "unprognostic (1.96e-2)" "unprognostic (2.65e-1)" 1.4 1.1 1.8 0.5 2.6 0.9 1.1 0.8 2.8 0.9 0.0 1.3 0.7 1.4 0.9 0.9 1.0 0.5 2.2 1.2 1.7 1.3 1.3 1.1 0.6 3.2 2.2 1.3 1.7 1.4 1.5 0.7 2.5 1.6 0.5 0.6 2.4 0.4 1.3 1.8 1.2 0.4 1.1 1.3 1.5 2.0 2.9 1.0 1.5 1.6 0.3 1.1 1.2 4.4 1.4 0.1 0.8 0.0 1.3 0.6 0.7 0.6 1.3 0.6 0.4 0.3 0.6 1.2 0.1 0.0 0.2 1.1 0.0 0.9 0.1 0.4 1.0 2.0 0.3 0.3 0.6 0.8 10.2 0.4 3.2 1.0 1.0 1.2 0.0 1.9 1.9 0.3 0.1 1.0 1.0 2.0 2.3 0.0 0.3 1.5 0.1 0.0 0.4 0.1 1.2 2.0 0.6 0.5 0.5 0.1 0.6 0.8 1.4 0.0 0.3 0.6 0.2 0.0 0.2 0.6 0.6 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.6 0.8 2.8 1.2 1.7 3.2 2.2 2.5 1.1 2.9 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 NVL NVL2 ENSG00000143748 "Nuclear VCP like" O15381 1 224227334-224330189 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028207, HPA028219, HPA028224, HPA028654" Supported Enhanced Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA028207: AB_10601382, HPA028219: AB_2672526, HPA028224: AB_2672529, HPA028654: AB_2672714" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (5.77e-5)" "prognostic favorable (2.95e-4)" "unprognostic (4.43e-2)" "unprognostic (7.14e-2)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "prognostic unfavorable (4.10e-11)" "unprognostic (1.67e-1)" "unprognostic (2.01e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" 7.0 7.7 5.5 8.7 5.7 9.8 10.7 7.8 7.5 9.5 6.5 9.1 6.3 9.0 7.7 7.2 8.8 5.6 5.9 5.3 6.4 8.7 6.1 8.0 12.5 5.4 5.3 10.6 8.8 9.5 10.3 13.0 5.6 9.0 10.6 12.8 7.4 7.9 6.5 15.7 8.2 8.1 4.7 10.4 7.2 6.6 5.6 13.0 10.2 5.2 12.1 8.8 8.9 7.5 28.8 15.8 31.2 25.2 11.5 16.6 31.6 22.0 16.5 30.6 27.0 23.4 23.4 39.6 22.5 14.7 11.7 26.1 37.3 22.2 31.5 30.5 47.0 16.4 25.5 11.3 20.3 39.1 28.8 13.5 16.9 26.8 28.5 14.3 19.2 23.0 48.9 23.8 19.1 21.3 30.6 18.3 47.5 20.0 26.1 34.2 37.3 24.8 17.8 19.2 27.5 22.9 34.2 53.1 31.9 25.6 24.3 32.1 19.8 23.2 14.9 27.1 42.9 15.6 33.3 39.3 15.1 30.2 24.8 13.9 7.8 8.4 11.5 11.8 11.7 13.5 11.8 9.1 8.7 9.0 9.9 10.0 0.8 11.9 16.4 9.0 9.3 7.8 5.5 5.7 7.8 7.5 5.3 6.4 5.4 5.3 5.6 4.7 5.6 7.5 10.2 22.4 23.1 21.2 14.3 5.2 4.6 7.8 4.0 14.5 7.9 8.3 10.5 7.2 12.2 1.8 10.4 21.5 12.6 26.9 13.7 9.5 10.1 10.0 11.6 9.3 4.2 7.2 32.1 8.4 14.0 9.3 5.6 7.3 16.4 13.4 4.6 4.5 10.7 10.1 31.0 12.6 10.2 6.5 5.7 3.1 9.6 8.1 5.4 26.2 8.7 9.7 15.5 24.6 43.0 7.0 23.4 10.9 12.3 3.7 7.0 8.1 16.7 20.4 0.0 8.5 10.1 17.5 11.3 7.3 4.5 18.3 12.9 11.4 14.7 3.7 NXPE1 "FAM55A, MGC34290" ENSG00000095110 "Neurexophilin and PC-esterase domain family member 1" Q8N323 11 114521645-114559895 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "intestine: 79.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 27.0;Early spermatids: 73.6;Intestinal goblet cells: 35.1;Late spermatids: 53.5;Paneth cells: 18.1;Undifferentiated cells: 36.2" "Cancer enriched" "Detected in single" 23 "colorectal cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049133 Enhanced "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA049133: AB_2680647" "unprognostic (2.81e-1)" "unprognostic (2.19e-3)" "unprognostic (3.40e-3)" "unprognostic (4.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 4.9 0.1 0.0 0.1 0.0 0.2 0.0 0.0 64.9 1.2 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.3 79.7 0.0 1.2 0.0 0.0 0.0 3.5 2.3 0.1 0.0 0.1 4.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.3 0.3 0.1 0.4 0.1 0.2 0.3 0.0 0.0 0.0 2.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 73.6 0.0 0.0 0.0 3.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 35.1 0.0 0.0 0.0 53.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.0 18.1 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 36.2 0.1 NXPE4 "C11orf33, FAM55D, FLJ20127" ENSG00000137634 "Neurexophilin and PC-esterase domain family member 4" Q6UWF7 11 114570591-114595786 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 119.6;salivary gland: 77.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 95.5;Intestinal goblet cells: 88.1;Paneth cells: 41.8;Undifferentiated cells: 115.8" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 13.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042801 Approved "Secreted to digestive system" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA042801: AB_10793986" "unprognostic (1.35e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-3)" "unprognostic (1.27e-1)" "unprognostic (3.51e-3)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (7.47e-3)" "unprognostic (4.36e-2)" "unprognostic (2.05e-1)" 0.1 0.0 0.1 7.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 114.2 0.6 0.2 6.8 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 5.3 119.6 0.0 77.2 0.2 0.0 0.0 0.7 5.2 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 0.0 0.0 0.5 0.0 0.0 0.0 17.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 41.8 0.0 0.1 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 115.8 0.2 OAS1 "IFI-4, OIAS, OIASI" ENSG00000089127 "2'-5'-oligoadenylate synthetase 1" P00973 12 112905856-112933219 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 91.0;urinary bladder: 111.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 151.0;Hofbauer cells: 105.6;Paneth cells: 127.9;Urothelial cells: 171.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 572.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 247.1;BJ hTERT+ SV40 Large T+ RasG12V: 336.6;OE19: 307.6;U-266/70: 272.9;U-266/84: 210.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003657, CAB021104" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "CAB021104: AB_10057722, HPA003657: AB_1854747" "unprognostic (1.03e-1)" "unprognostic (6.59e-2)" "unprognostic (8.56e-3)" "unprognostic (2.20e-3)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.20e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (5.37e-2)" "unprognostic (1.63e-2)" "unprognostic (6.91e-2)" "unprognostic (3.68e-2)" "unprognostic (5.67e-2)" "prognostic favorable (6.12e-6)" 17.0 11.5 6.8 27.3 7.3 14.3 13.1 6.5 9.7 29.6 6.1 49.0 51.7 8.0 8.1 57.1 10.0 22.5 9.5 6.6 6.9 22.3 38.6 23.1 27.2 15.4 8.0 8.1 4.4 9.0 8.3 20.4 11.5 9.1 45.1 1.5 91.0 7.3 2.4 10.3 39.8 14.6 21.2 50.5 43.6 4.8 8.4 28.1 7.7 7.4 25.6 111.1 22.7 9.9 4.7 24.4 0.0 0.1 9.4 6.6 1.5 0.1 38.8 247.1 336.6 18.5 34.1 42.3 12.2 0.3 121.8 10.8 0.2 4.2 2.2 21.0 0.0 0.7 35.2 4.6 2.9 0.6 1.4 0.5 7.2 8.0 0.0 3.1 13.5 0.7 0.0 17.4 0.2 0.4 0.6 17.0 0.7 307.6 22.5 5.8 0.2 20.5 11.6 89.4 0.2 0.9 3.7 4.2 85.2 0.4 0.9 5.1 50.4 0.0 0.5 3.2 0.4 272.9 210.3 23.9 2.9 6.6 1.4 6.3 253.6 3.2 26.5 403.9 25.3 108.8 36.3 34.3 153.9 93.1 14.3 18.8 24.4 24.9 572.0 144.5 108.7 217.8 6.8 7.3 6.5 9.7 6.6 6.9 15.4 8.0 11.5 21.2 8.4 9.9 23.0 3.2 2.2 0.0 21.1 3.4 16.6 24.0 10.8 0.2 6.0 8.1 3.1 14.3 35.4 5.5 0.0 12.6 31.5 151.0 5.9 19.5 0.4 1.9 3.6 17.2 4.2 3.6 0.6 12.0 36.4 11.1 28.5 4.1 5.1 15.4 14.3 11.9 105.6 0.0 1.0 59.3 26.4 36.9 11.4 1.2 7.2 52.9 5.4 13.1 36.2 15.0 18.6 3.5 0.1 19.5 127.9 10.5 24.1 7.4 50.9 25.4 17.5 0.4 6.6 3.0 7.5 0.0 0.5 18.3 2.3 5.7 9.1 12.7 14.6 171.9 OASL "OASL1, p59OASL, TRIP14" ENSG00000135114 "2'-5'-oligoadenylate synthetase like" Q15646 12 121017763-121039242 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.7;stomach 1: 22.3" "Cell type enhanced" "Detected in many" "dendritic cells: 54.1;Distal enterocytes: 82.3;Gastric mucus-secreting cells: 97.9;Paneth cells: 71.4;T-cells: 43.9;Urothelial cells: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 132.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 126.9;BJ hTERT+ SV40 Large T+ RasG12V: 66.2;GAMG: 35.3;hTEC/SVTERT24-B: 50.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA001474 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA001474: AB_1079518" "unprognostic (2.39e-2)" "unprognostic (7.50e-2)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (1.62e-2)" "unprognostic (6.22e-2)" "unprognostic (5.93e-3)" "prognostic unfavorable (9.20e-4)" "unprognostic (4.61e-1)" "prognostic unfavorable (3.70e-9)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (3.17e-2)" 2.3 0.8 0.7 4.2 0.8 35.7 2.4 0.7 0.8 3.3 0.6 7.5 2.7 0.5 0.5 4.0 0.7 3.6 1.1 0.6 0.5 2.3 11.8 11.9 3.6 1.4 0.7 0.4 0.7 0.1 0.6 1.4 1.4 0.5 3.4 0.2 4.1 0.4 0.4 0.9 2.0 1.3 3.3 5.3 22.3 2.1 1.1 3.3 1.1 0.6 1.7 7.8 1.4 0.9 2.6 0.6 0.2 0.9 1.0 1.6 0.1 0.2 0.9 126.9 66.2 0.3 13.0 0.6 4.0 0.1 35.3 6.4 0.1 0.9 7.2 25.2 0.1 0.1 13.8 0.0 0.7 0.2 1.8 0.8 0.6 50.7 0.1 0.3 0.3 1.0 0.1 5.3 1.1 1.7 0.1 3.1 0.1 4.5 3.7 0.1 0.2 1.4 0.1 13.7 0.1 0.2 1.1 0.6 18.5 0.1 0.4 1.7 0.1 0.7 1.2 2.1 0.2 4.9 10.1 0.3 19.9 1.3 0.4 12.3 29.6 65.8 53.1 32.5 14.3 2.5 36.2 62.1 8.9 0.8 9.9 38.5 132.8 20.3 23.5 0.5 27.8 33.2 0.7 0.8 0.7 0.8 0.6 0.5 1.4 0.7 1.4 3.3 1.1 0.9 28.6 0.0 4.2 0.7 4.6 2.2 5.0 2.7 1.8 0.0 3.3 4.7 0.6 1.5 3.9 0.0 0.0 0.2 54.1 82.3 0.0 2.5 6.6 2.0 0.6 4.5 1.8 0.8 0.2 3.8 1.3 2.4 97.9 2.8 11.4 1.0 2.2 4.5 12.6 0.0 0.2 30.7 4.1 3.1 7.2 3.4 0.3 16.7 0.0 1.0 6.0 0.0 9.2 0.0 0.0 12.7 71.4 0.0 14.3 2.2 2.4 0.3 3.8 0.0 0.0 0.7 2.8 2.4 0.1 14.6 1.0 0.1 43.9 0.2 5.1 96.3 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OR2B2 "hs6M1-10, OR2B2Q, OR2B9, OR6-1" ENSG00000168131 "Olfactory receptor family 2 subfamily B member 2" Q9GZK3 6 27911185-27912396 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR2F1 "OLF3, OR14-60, OR2F3, OR2F3P, OR2F4, OR2F5, OR7-139, OR7-140" ENSG00000213215 "Olfactory receptor family 2 subfamily F member 1" Q13607 7 143954844-143997312 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Intestinal epithelial cells - Unknown function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OTOP2 ENSG00000183034 "Otopetrin 2" Q7RTS6 17 74922950-74933912 "Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 20.1" "Cell type enriched" "Detected in some" 20 "Paneth cells: 627.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 41 "HDLM-2: 10.1" "Region enriched" "Detected in some" 12 "olfactory bulb: 12.7" "Low region specificity" "Detected in many" "HPA024524, HPA053090" Uncertain Approved "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA024524: AB_2671592, HPA053090: AB_2682041" "unprognostic (1.62e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (3.21e-2)" "unprognostic (3.62e-1)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.81e-1)" "unprognostic (9.04e-2)" "unprognostic (2.04e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.3 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.1 0.0 0.2 1.4 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 30.0 0.0 0.0 9.3 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 19.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 627.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 4.1 0.0 OTUB1 "FLJ20113, FLJ40710" ENSG00000167770 "OTU deubiquitinase, ubiquitin aldehyde binding 1" Q96FW1 11 63985853-64001811 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, DNA damage, DNA repair, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039176, CAB072836" Approved Supported Approved Nucleoplasm,Cytosol NA NA 500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "CAB072836: , HPA039176: AB_10674980" "unprognostic (2.50e-1)" "unprognostic (5.70e-3)" "unprognostic (3.93e-2)" "unprognostic (1.63e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.45e-1)" "unprognostic (1.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (6.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.84e-2)" "unprognostic (1.82e-1)" 44.8 57.0 69.9 43.0 78.0 63.5 47.3 53.0 93.4 54.1 39.7 51.9 42.0 49.0 37.4 85.4 55.8 35.9 62.4 79.3 62.5 61.3 47.0 47.1 59.8 65.0 58.0 44.5 43.9 47.1 48.6 49.3 66.1 53.5 39.3 25.6 54.3 42.6 70.2 78.1 51.9 38.0 51.2 58.6 54.0 57.1 65.0 56.0 51.9 48.4 57.1 52.5 56.7 67.7 113.4 198.9 107.2 95.7 70.7 77.8 83.0 66.0 97.1 143.6 105.1 138.1 104.5 59.3 122.0 106.6 124.4 138.1 140.4 165.4 88.1 69.9 111.7 99.3 114.1 172.9 98.8 99.2 104.3 83.4 106.4 110.2 69.8 74.4 137.2 54.6 71.2 65.3 97.9 237.2 109.2 133.0 126.5 95.4 94.1 88.3 41.8 102.5 151.1 162.1 81.5 117.5 74.6 114.1 123.3 72.9 178.2 86.3 100.1 75.8 74.2 103.3 88.4 76.2 51.7 86.4 98.4 64.0 74.5 228.8 186.8 189.9 165.5 244.2 131.2 149.6 152.1 153.6 203.1 139.3 117.1 130.4 184.6 161.8 218.9 140.7 224.7 313.4 69.9 78.0 53.0 93.4 79.3 62.5 65.0 58.0 66.1 51.2 65.0 67.7 37.0 19.2 56.5 15.0 67.2 48.3 70.9 137.8 83.6 44.4 42.5 48.8 31.9 37.1 82.5 46.0 39.6 146.2 56.5 104.7 74.3 80.7 72.6 55.4 36.2 43.4 87.8 35.5 17.8 85.5 109.2 50.0 71.9 44.3 48.7 54.6 35.7 33.2 90.4 30.3 16.9 70.8 101.7 57.4 65.9 87.1 34.2 61.0 51.6 8.4 98.0 43.2 78.2 12.5 18.8 90.1 92.0 25.6 80.8 51.8 90.8 85.2 89.2 55.7 26.3 28.1 62.0 48.0 71.4 77.7 52.6 194.8 73.7 51.7 62.7 71.6 P2RX4 P2X4 ENSG00000135124 "Purinergic receptor P2X 4" Q99571 12 121209861-121234106 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 135.3;Distal enterocytes: 133.7;Hofbauer cells: 129.5;Syncytiotrophoblasts: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039494 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA039494: AB_10969132" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" "unprognostic (5.43e-2)" "prognostic favorable (6.30e-10)" "unprognostic (2.98e-2)" "unprognostic (2.52e-1)" "unprognostic (2.06e-3)" "unprognostic (1.68e-1)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (7.71e-2)" "unprognostic (2.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.13e-1)" "unprognostic (6.06e-2)" "unprognostic (1.42e-2)" "unprognostic (4.76e-3)" 10.1 9.9 4.8 15.1 5.0 14.1 12.7 8.3 5.6 18.8 4.6 33.5 28.9 8.5 3.7 5.0 15.3 16.8 7.2 5.1 5.3 13.0 11.5 20.4 15.9 6.7 5.4 18.1 37.4 33.1 5.1 32.7 6.0 12.1 30.2 2.0 30.1 12.0 1.0 4.5 32.8 10.7 6.3 12.6 20.2 6.0 6.3 7.8 12.9 2.3 8.9 12.1 4.1 7.6 6.6 15.4 1.1 21.7 10.3 8.3 40.6 4.9 26.1 6.7 13.3 10.9 23.1 6.4 18.5 17.4 48.2 2.3 4.7 3.2 4.1 17.5 11.8 3.1 0.9 12.5 25.3 7.6 42.5 11.9 6.8 11.0 14.5 20.4 24.2 7.7 6.1 16.2 5.0 31.8 4.7 10.7 5.5 31.8 10.5 6.6 29.5 34.6 3.1 18.0 6.1 9.0 16.0 8.8 55.0 5.7 38.5 21.2 2.1 10.0 11.2 1.2 5.2 28.0 26.1 3.7 19.6 10.2 9.1 72.3 59.1 10.7 13.6 63.1 15.1 11.3 21.9 13.3 32.5 7.1 16.4 9.6 0.8 29.6 54.6 4.4 17.1 32.6 4.8 5.0 8.3 5.6 5.1 5.3 6.7 5.4 6.0 6.3 6.3 7.6 8.4 6.4 19.2 6.5 14.0 3.8 8.9 11.9 6.8 11.1 17.7 11.9 3.8 21.5 11.2 20.2 2.1 135.3 13.7 133.7 0.0 69.7 15.2 9.8 8.9 9.2 21.5 2.1 6.4 35.4 73.8 14.3 19.4 15.1 13.9 14.3 23.6 9.4 129.5 15.2 5.3 90.3 20.3 43.7 20.8 25.1 8.7 53.7 10.6 18.7 57.9 6.5 19.6 4.5 8.0 33.1 80.6 9.8 21.9 10.2 98.7 23.2 6.4 8.6 19.7 7.4 12.0 8.1 6.6 3.4 4.0 155.7 17.8 15.4 24.7 9.7 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119451 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 240.6;skeletal muscle: 311.8;tongue: 492.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.9;Distal enterocytes: 178.7;Intestinal goblet cells: 77.3;Oligodendrocytes: 117.1;Paneth cells: 72.3" "Cancer enhanced" "Detected in many" "glioma: 24.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 43.3;neutrophil: 100.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 100.6" "Cell line enhanced" "Detected in some" "A549: 11.6;RPTEC TERT1: 33.1;SK-BR-3: 50.7;T-47d: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047735: AB_2680139" "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 0.9 85.9 9.3 161.5 23.7 41.1 164.3 103.9 3.3 33.5 89.8 1.4 0.8 0.6 6.1 2.7 1.6 0.6 82.2 165.1 12.7 0.7 4.4 1.0 205.8 167.0 0.2 1.5 2.1 3.7 1.4 212.0 2.6 92.3 50.5 44.4 1.6 311.8 9.6 8.4 5.8 189.3 13.4 2.2 0.8 144.3 2.1 0.6 492.3 1.3 2.5 1.0 240.6 0.0 11.6 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.1 0.1 0.1 4.9 0.2 1.5 0.5 0.1 1.6 0.4 0.1 0.3 0.0 0.8 0.5 0.0 0.0 0.0 0.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 3.8 0.6 1.4 1.6 3.9 0.0 0.0 0.0 0.4 33.1 0.0 2.1 0.2 0.0 50.7 0.0 2.7 13.9 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.9 0.0 1.3 16.2 43.3 0.0 0.9 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 100.6 0.0 0.2 0.4 0.0 6.4 85.9 161.5 164.3 103.9 82.2 165.1 205.8 167.0 212.0 189.3 144.3 240.6 0.2 0.0 1.3 28.4 1.0 0.3 0.4 0.6 0.0 2.2 31.2 32.5 0.4 0.0 3.3 1.8 95.9 0.2 0.7 178.7 11.7 0.6 6.1 0.0 0.0 8.2 3.6 0.0 1.5 0.0 0.5 0.6 0.0 0.1 17.1 0.5 0.7 0.0 7.2 0.0 1.4 77.3 2.0 4.8 25.8 10.3 0.3 9.2 28.4 15.9 33.8 33.6 0.0 13.6 117.1 0.0 72.3 0.7 0.4 0.5 15.0 0.3 0.2 29.6 0.0 5.6 1.3 0.2 0.4 0.0 0.4 0.1 0.4 0.0 51.8 0.2 PANK3 FLJ12899 ENSG00000120137 "Pantothenate kinase 3" Q9H999 5 168548495-168579368 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078669 Approved Approved "Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA078669: " "unprognostic (1.24e-2)" "unprognostic (5.71e-2)" "prognostic favorable (3.94e-4)" "unprognostic (7.65e-3)" "unprognostic (2.47e-2)" "unprognostic (2.42e-2)" "unprognostic (1.20e-2)" "unprognostic (8.43e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (9.48e-2)" "unprognostic (2.30e-1)" "unprognostic (3.71e-2)" "unprognostic (1.05e-1)" "unprognostic (1.43e-1)" "unprognostic (1.97e-3)" "unprognostic (2.01e-1)" 12.5 20.1 6.8 13.5 8.3 17.9 25.5 20.4 10.0 10.5 2.6 27.0 41.5 13.2 9.3 13.1 7.9 10.0 10.3 8.5 7.9 15.0 43.2 10.3 13.1 8.8 8.7 11.3 10.5 21.8 6.3 14.1 8.5 12.8 25.7 18.0 10.5 7.8 7.7 14.9 30.5 11.7 7.6 12.7 16.1 12.5 9.4 14.2 15.2 12.1 12.5 11.5 11.2 10.4 29.0 16.1 65.2 34.9 23.8 27.5 27.5 17.1 18.0 22.3 32.5 26.9 26.1 44.9 27.3 24.3 35.6 20.3 44.2 34.2 40.1 42.1 21.6 23.4 15.2 20.1 27.7 31.1 29.4 22.1 45.4 28.1 31.4 15.8 26.5 33.1 21.5 43.4 31.0 16.0 31.3 14.1 27.7 22.2 12.1 22.3 44.8 18.2 28.1 42.2 30.2 64.4 19.6 31.5 48.9 32.6 41.2 38.8 27.8 29.9 41.3 17.9 36.8 30.0 45.1 32.5 17.8 31.3 23.8 1.1 1.0 0.5 0.5 1.2 0.7 1.4 0.6 0.6 0.6 0.5 0.4 0.7 0.4 0.3 1.7 0.9 0.7 0.3 6.8 8.3 20.4 10.0 8.5 7.9 8.8 8.7 8.5 7.6 9.4 10.4 26.3 25.6 19.3 6.2 18.3 34.3 23.6 27.4 4.6 28.7 59.1 29.0 16.4 17.2 26.4 25.8 27.1 17.6 29.9 114.8 9.8 17.9 12.8 20.4 28.7 24.8 34.2 36.4 23.3 20.1 14.2 22.0 36.7 32.4 15.2 31.4 14.3 94.2 23.0 28.6 22.6 37.5 26.4 33.6 30.5 17.0 16.8 25.0 23.2 10.3 23.1 12.6 14.4 12.5 17.5 23.0 40.4 17.7 17.0 40.1 98.3 27.2 22.7 26.4 26.3 30.7 28.0 42.1 25.1 26.7 56.1 41.9 18.0 42.4 50.6 52.3 PAQR8 "C6orf33, LMPB1, MPRB" ENSG00000170915 "Progestin and adipoQ receptor family member 8" Q8TEZ7 6 52361421-52407777 "Predicted membrane proteins, Transporters" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 144.9" "Cell type enhanced" "Detected in many" "Astrocytes: 168.5;Distal enterocytes: 154.3;Microglial cells: 74.0;Oligodendrocytes: 298.2;Paneth cells: 80.7;Proximal enterocytes: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 41.8;OE19: 87.9;SuSa: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064625 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA064625: AB_2685304" "prognostic favorable (4.61e-4)" "unprognostic (7.39e-3)" "unprognostic (2.77e-3)" "unprognostic (8.23e-2)" "unprognostic (4.33e-1)" "unprognostic (4.08e-3)" "unprognostic (2.66e-2)" "unprognostic (5.67e-2)" "unprognostic (6.37e-2)" "unprognostic (4.30e-3)" "unprognostic (2.10e-1)" "unprognostic (5.55e-2)" "unprognostic (8.82e-3)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (3.14e-2)" "prognostic favorable (6.40e-4)" 2.7 4.0 83.7 9.2 113.9 1.2 2.3 122.9 86.7 4.7 42.0 38.9 19.3 5.1 8.0 17.6 6.3 6.0 3.5 74.4 89.7 8.0 1.5 7.3 10.3 133.8 110.7 24.3 2.8 5.2 2.2 7.0 123.1 4.3 36.7 2.9 2.2 23.3 0.9 3.1 33.7 6.3 102.8 6.2 32.3 3.7 106.4 9.2 2.8 1.5 7.6 9.7 5.5 144.9 0.9 1.0 10.7 4.6 6.3 10.2 7.3 3.2 12.1 2.0 4.4 4.1 3.8 1.1 1.2 2.2 4.7 0.4 1.4 5.3 3.2 14.8 1.7 6.6 1.0 41.8 1.7 1.8 0.9 2.9 0.7 1.4 7.5 7.4 11.5 12.9 1.5 6.4 8.3 1.5 4.4 6.1 5.4 87.9 0.5 11.5 1.7 2.8 12.4 3.1 4.0 8.7 0.8 0.3 12.4 34.4 0.3 14.7 4.8 4.0 1.6 1.2 1.9 1.9 2.6 1.6 3.7 16.9 21.5 3.0 3.2 1.4 2.8 0.6 4.2 1.1 8.3 5.7 7.0 1.0 17.8 8.3 0.6 8.5 0.6 3.5 6.2 4.2 83.7 113.9 122.9 86.7 74.4 89.7 133.8 110.7 123.1 102.8 106.4 144.9 4.9 3.2 10.6 168.5 3.6 2.0 3.7 3.1 0.6 2.1 0.7 1.3 4.4 14.3 3.5 3.7 8.4 1.7 7.6 154.3 0.0 4.4 0.5 12.2 3.9 7.4 22.9 4.2 21.1 1.1 3.1 6.8 18.8 7.5 4.5 23.7 4.2 0.2 8.8 0.0 19.4 45.5 6.1 19.8 3.5 1.6 5.6 7.3 14.2 74.0 11.4 4.2 3.1 19.1 298.2 4.9 80.7 10.1 0.6 6.6 100.5 0.1 8.9 3.3 0.0 1.0 3.6 12.1 3.3 5.3 1.0 0.8 9.2 10.0 42.5 7.3 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Distal enterocytes: 66.4;Exocrine glandular cells: 46.3;Pancreatic endocrine cells: 65.2;Urothelial cells: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 86.1;HaCaT: 108.0;HUVEC TERT2: 56.2;OE19: 77.8;RT4: 74.2;TIME: 74.5;WM-115: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" 24.0 4.0 11.7 7.7 15.9 1.2 22.8 3.3 15.1 11.6 0.0 23.1 21.4 9.2 6.4 41.7 9.1 6.6 19.3 17.0 2.3 21.3 19.3 27.7 2.0 0.0 0.8 2.5 13.8 3.8 6.5 19.2 0.0 10.8 14.3 3.4 28.8 11.2 8.2 27.4 17.1 7.2 1.1 1.8 23.6 1.1 2.7 1.0 12.6 11.1 9.1 9.8 19.2 5.7 18.9 1.0 7.7 8.5 0.3 0.0 5.5 0.2 0.2 0.1 0.0 4.5 86.1 0.1 43.7 0.6 1.0 108.0 9.9 7.9 0.0 0.1 0.3 0.0 0.4 0.1 6.9 0.0 0.3 0.0 17.8 0.1 1.2 18.1 56.2 0.0 0.1 9.2 0.0 15.1 0.3 0.0 32.5 77.8 14.6 0.3 0.1 13.2 6.3 74.2 0.9 1.8 0.5 23.3 20.0 21.6 18.8 0.4 74.5 0.1 0.7 0.1 6.9 0.0 0.1 0.2 0.5 0.0 52.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 11.7 15.9 3.3 15.1 17.0 2.3 0.0 0.8 0.0 1.1 2.7 5.7 61.5 0.0 5.3 3.6 0.2 1.0 12.0 4.6 0.0 9.6 9.5 4.7 4.4 20.0 8.6 12.9 0.0 0.7 2.0 66.4 3.9 15.3 1.3 10.1 2.1 34.2 7.7 2.7 12.3 46.3 0.3 2.6 21.9 21.3 0.0 0.0 7.5 30.1 0.2 26.9 6.1 21.3 12.2 1.4 2.3 2.5 0.6 0.5 0.0 6.5 0.0 4.8 7.2 5.5 7.2 65.2 30.3 0.4 1.4 25.8 36.4 5.2 7.1 0.5 13.1 0.9 18.5 0.3 0.2 7.4 2.6 20.1 0.9 0.5 18.9 54.5 PDCD6IP "AIP1, Alix, Hp95" ENSG00000170248 "Programmed cell death 6 interacting protein" Q8WUM4 3 33798571-33869707 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 299.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA011905, CAB016212, HPA051604" Approved Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 4100000 "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Centrosome "CAB016212: AB_673819, HPA011905: AB_1855111, HPA051604: " "unprognostic (1.53e-1)" "unprognostic (2.63e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.17e-1)" "unprognostic (2.75e-1)" "unprognostic (5.12e-2)" "unprognostic (7.76e-3)" "unprognostic (1.23e-2)" "unprognostic (3.29e-1)" "unprognostic (2.86e-1)" "unprognostic (3.88e-3)" "unprognostic (4.49e-2)" "prognostic favorable (3.90e-9)" "unprognostic (9.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.78e-1)" "unprognostic (1.11e-1)" 33.1 27.6 16.3 24.5 17.9 21.2 32.9 18.4 23.3 35.0 23.0 46.4 36.2 35.1 26.4 46.0 30.9 25.9 30.5 17.6 19.7 35.0 33.2 35.2 26.1 25.2 18.1 34.3 25.0 40.6 22.8 31.2 26.4 30.0 41.5 30.5 29.7 23.7 33.9 39.8 38.8 31.8 18.6 27.5 37.2 23.8 18.8 24.4 34.2 22.1 30.1 26.9 35.9 21.4 47.2 46.4 30.2 25.1 78.5 80.6 34.3 67.2 56.2 50.9 52.2 33.3 43.8 75.9 33.8 77.7 32.2 45.5 47.8 61.4 57.8 27.4 39.5 56.7 37.4 28.2 50.8 56.5 57.6 62.2 69.5 57.6 67.8 60.5 77.1 32.4 50.3 26.2 74.4 27.0 36.3 31.8 29.9 43.5 57.8 32.8 36.5 43.8 64.6 39.2 14.7 26.8 61.6 67.8 30.7 48.9 62.0 51.4 101.1 59.5 28.2 50.1 46.9 26.6 37.6 55.6 56.7 62.6 28.8 6.8 13.5 11.0 8.0 18.1 8.7 12.0 8.9 8.1 12.4 10.8 7.7 7.5 6.8 12.1 18.0 5.0 9.4 10.0 16.3 17.9 18.4 23.3 17.6 19.7 25.2 18.1 26.4 18.6 18.8 21.4 78.5 86.6 84.8 85.8 76.1 41.7 62.6 62.7 51.8 28.6 42.5 34.0 53.4 62.9 80.6 64.4 52.1 53.0 58.5 299.9 37.2 67.2 85.3 121.6 84.0 68.8 36.1 40.6 83.5 78.3 52.8 54.3 96.8 77.8 53.7 53.0 54.3 57.3 60.6 25.2 69.2 97.1 63.1 93.0 44.7 50.4 74.0 85.0 28.4 75.9 71.0 23.1 42.2 96.0 161.7 122.5 127.1 80.5 46.9 56.5 130.2 61.0 130.9 49.9 46.0 42.3 50.4 93.0 48.4 61.5 43.2 96.6 55.2 47.7 86.7 70.3 PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18208652-18248200 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 21.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 255.9;Gastric mucus-secreting cells: 141.2;Paneth cells: 251.4;Proximal enterocytes: 73.0;Skeletal myocytes: 106.5;Undifferentiated cells: 103.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 1.2;cerebral cortex: 1.1" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Cell line enhanced" "Detected in some" "BEWO: 2.9;Hep G2: 2.0;U-87 MG: 4.4" "HPA048975, HPA054218" Approved Approved "Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centrosome, Cytosol" "Midbody ring" "HPA048975: AB_2680581, HPA054218: " "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (5.22e-4)" "unprognostic (1.44e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (4.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-3)" "unprognostic (2.21e-1)" "unprognostic (7.25e-10)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (9.21e-2)" "unprognostic (2.45e-2)" 1.4 0.6 0.2 0.1 1.2 0.5 0.7 0.0 1.1 3.2 0.0 4.3 0.7 3.4 3.4 0.7 3.0 1.1 4.4 0.2 0.0 4.8 1.3 3.4 0.2 0.0 0.0 1.8 0.7 0.2 2.8 3.7 0.0 2.3 0.6 0.2 0.5 2.7 8.3 0.3 2.4 1.8 0.0 2.1 3.8 2.5 0.0 0.0 1.1 21.3 0.1 1.0 1.7 0.0 0.0 0.1 0.0 0.1 0.0 0.1 2.9 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.0 0.1 0.0 0.2 0.3 0.0 1.2 0.0 0.2 0.0 0.1 0.4 0.9 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.4 0.1 0.2 0.0 0.7 0.2 0.2 0.0 0.1 0.0 0.3 0.0 0.6 0.3 0.1 4.4 0.1 0.0 1.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.0 0.0 0.2 1.2 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.2 10.6 2.0 0.8 5.5 5.8 8.6 5.2 3.9 0.2 0.4 35.3 4.3 22.4 0.0 6.2 2.1 0.0 255.9 0.0 0.0 32.9 0.1 0.1 4.6 7.2 0.0 8.2 0.0 4.3 6.3 141.2 0.1 4.5 0.0 1.1 0.3 0.5 0.0 2.1 55.2 4.1 1.4 4.5 38.4 0.6 2.1 1.8 0.0 0.4 1.9 1.0 0.5 0.9 0.0 251.4 4.1 1.6 1.8 73.0 0.0 9.4 3.0 46.0 106.5 17.2 1.9 2.2 28.6 3.8 1.1 1.2 0.0 103.3 17.3 PDLIM1 "CLIM1, CLP-36, CLP36, hCLIM1" ENSG00000107438 "PDZ and LIM domain 1" O00151 10 95237572-95291012 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 675.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 805.9;Basal respiratory cells: 763.8;Paneth cells: 769.2;Proximal enterocytes: 1059.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 189.7;memory B-cell: 223.8;naive B-cell: 213.0" "Group enriched" "Detected in all" 7 "B-cells: 223.8;granulocytes: 189.7" "Cell line enhanced" "Detected in many" "HaCaT: 766.3;Hep G2: 635.3;HHSteC: 731.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017010, CAB072838, CAB072840" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 93000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane, Cell Junctions" "CAB072838: , CAB072840: , HPA017010: AB_1855147" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.58e-2)" "prognostic favorable (1.14e-5)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (2.07e-1)" "unprognostic (8.99e-2)" "unprognostic (2.26e-1)" "unprognostic (2.82e-3)" "unprognostic (5.77e-2)" "unprognostic (6.56e-2)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-1)" "unprognostic (4.21e-3)" "unprognostic (1.11e-1)" 301.7 32.4 10.7 91.5 10.8 25.0 236.0 10.2 18.5 133.1 30.2 220.0 179.4 115.0 91.8 182.3 155.3 114.9 393.2 11.7 10.9 82.8 160.3 337.2 104.5 20.4 12.7 35.6 98.3 65.9 29.5 141.1 14.1 116.9 218.5 36.9 166.1 114.7 675.1 136.8 249.0 146.0 14.0 148.3 148.3 13.7 13.8 105.9 194.7 290.0 123.7 276.3 165.3 11.2 274.4 181.8 12.4 0.4 64.1 43.3 277.1 82.6 266.4 218.8 356.5 387.0 429.8 0.3 21.9 233.8 110.4 766.3 91.5 498.1 220.6 0.2 132.0 277.9 50.1 635.3 731.0 0.1 13.2 125.5 257.0 111.9 400.6 233.2 396.8 24.2 60.0 70.3 52.7 51.4 0.8 4.9 24.6 137.7 137.2 234.1 10.0 98.4 114.4 268.9 48.3 18.9 91.2 84.6 0.9 293.8 68.2 125.7 345.1 84.5 19.7 0.7 0.7 31.2 0.1 91.6 92.5 0.2 41.0 0.4 2.4 189.7 11.9 0.8 0.1 223.8 2.3 14.1 31.0 213.0 0.5 8.1 7.5 8.9 1.5 3.2 2.2 44.5 10.7 10.8 10.2 18.5 11.7 10.9 20.4 12.7 14.1 14.0 13.8 11.2 435.0 76.9 123.5 0.0 145.6 366.3 805.9 763.8 244.7 10.1 100.6 131.4 266.2 223.1 250.2 51.5 29.2 538.2 20.5 657.0 15.6 420.1 8.4 218.6 319.3 359.3 101.3 41.6 0.9 172.5 116.7 149.2 100.9 113.0 12.6 47.2 459.7 100.4 50.0 1.7 0.4 488.9 152.5 19.4 105.2 8.0 5.0 88.8 40.9 2.8 8.8 11.6 32.0 0.0 0.0 227.0 769.2 0.7 103.5 256.5 1059.7 109.0 316.4 59.5 315.5 21.0 213.1 4.3 35.7 170.4 197.9 117.0 25.8 1.9 419.2 554.3 PDZD3 "FLJ22756, IKEPP, PDZK2" ENSG00000172367 "PDZ domain containing 3" Q86UT5 11 119185457-119190223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 19.3;kidney: 17.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 93.4;Gastric mucus-secreting cells: 30.5;Paneth cells: 74.8;Proximal enterocytes: 79.1;Proximal tubular cells: 29.5;Undifferentiated cells: 21.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.3;renal cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA077887 Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA077887: " "unprognostic (2.42e-2)" "unprognostic (1.51e-1)" "unprognostic (2.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-2)" "unprognostic (6.07e-2)" "unprognostic (3.22e-1)" "unprognostic (1.86e-2)" "unprognostic (6.58e-3)" "unprognostic (9.00e-2)" "unprognostic (6.08e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (3.41e-3)" 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 17.1 0.0 0.0 0.0 1.0 2.8 0.1 0.0 0.0 17.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 19.3 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.3 8.6 0.0 0.0 6.2 0.0 0.0 93.4 3.9 0.1 0.0 0.2 0.1 0.2 1.2 0.0 0.0 0.2 0.0 0.4 30.5 0.1 0.0 0.1 1.1 0.1 0.2 0.0 0.0 8.5 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 74.8 0.0 0.2 0.1 79.1 29.5 0.7 0.7 0.0 0.5 0.1 0.0 0.0 0.3 0.1 0.0 0.2 0.1 21.0 0.1 PEX11A "MGC119947, MGC138534, PEX11-ALPHA" ENSG00000166821 "Peroxisomal biogenesis factor 11 alpha" O75192 15 89677764-89690783 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 38.7;Late spermatids: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (1.40e-1)" "unprognostic (6.17e-2)" "unprognostic (6.80e-3)" "unprognostic (2.82e-2)" "unprognostic (2.38e-1)" "unprognostic (3.24e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-2)" "unprognostic (5.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.32e-2)" 25.6 10.4 7.9 3.4 8.3 0.8 20.0 6.9 8.5 7.2 12.8 14.5 16.3 6.0 10.5 6.5 9.6 5.4 8.1 7.9 8.7 11.7 39.1 6.1 2.5 7.1 7.8 13.1 11.8 10.0 5.5 3.6 7.2 18.3 12.0 12.7 11.3 10.1 17.9 5.4 12.2 5.5 7.2 4.1 11.3 11.4 9.0 2.3 10.9 12.0 3.7 9.2 6.1 7.9 10.2 6.1 4.6 0.3 23.4 8.4 3.7 5.0 8.5 7.4 12.0 4.3 11.9 4.7 5.5 5.8 10.6 13.3 0.0 7.6 8.5 7.5 16.8 7.1 7.2 6.0 16.8 4.7 2.4 10.4 9.2 4.3 7.1 5.8 5.2 4.6 0.1 1.8 5.6 10.2 0.0 0.6 2.6 20.6 11.1 0.0 0.0 4.2 6.1 6.8 3.4 8.7 16.0 54.4 15.5 8.3 14.4 4.4 4.7 4.9 4.8 13.2 4.0 5.3 9.5 0.2 11.9 0.7 4.3 1.2 0.7 2.3 3.6 1.0 2.0 1.6 1.8 2.0 1.8 0.9 2.2 2.5 0.8 3.1 0.7 0.4 1.7 1.5 7.9 8.3 6.9 8.5 7.9 8.7 7.1 7.8 7.2 7.2 9.0 7.9 1.5 6.4 8.4 12.4 2.0 1.8 9.3 5.2 7.4 8.6 15.3 10.9 8.7 10.0 11.4 5.5 2.1 10.8 1.3 22.1 5.9 7.6 24.8 7.1 5.5 3.1 3.6 0.8 3.0 4.6 7.1 4.6 3.1 5.2 1.3 6.2 4.6 38.7 4.0 18.5 3.5 8.9 6.1 3.5 0.8 39.0 5.3 1.6 3.6 2.8 1.9 14.5 1.0 3.5 3.5 5.5 11.6 2.6 0.6 11.5 20.7 12.6 16.2 9.7 0.0 6.4 4.6 22.6 8.7 5.0 2.0 2.7 1.5 11.0 11.8 11.9 PEX26 FLJ20695 ENSG00000215193 "Peroxisomal biogenesis factor 26" Q7Z412 22 18077923-18105396 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.7;Proximal enterocytes: 91.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB070429 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB070429: AB_11154363" "unprognostic (2.25e-1)" "unprognostic (5.75e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.77e-3)" "unprognostic (5.46e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.10e-4)" "unprognostic (1.59e-2)" "unprognostic (5.34e-2)" "unprognostic (8.19e-2)" "unprognostic (1.88e-2)" "unprognostic (1.96e-1)" "prognostic favorable (1.38e-4)" "unprognostic (3.17e-3)" "unprognostic (4.53e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" 7.5 5.8 7.3 7.8 6.2 12.1 6.7 3.7 6.8 4.9 5.8 16.9 19.2 5.5 5.3 7.5 6.0 5.3 5.8 7.9 5.3 7.5 7.3 5.0 7.3 8.4 7.8 5.4 8.0 9.2 4.2 5.0 7.0 5.3 13.1 3.1 6.4 5.6 6.3 5.6 19.9 5.4 6.3 8.1 9.3 3.1 8.3 7.3 6.9 4.1 6.7 6.0 3.9 5.5 18.3 8.7 10.2 9.2 10.5 6.6 18.8 11.8 12.2 12.8 10.5 15.2 15.1 11.3 10.8 17.5 11.2 18.7 15.9 16.5 10.9 19.0 12.4 19.4 12.3 12.8 10.0 26.0 23.6 8.2 12.7 17.3 16.2 6.1 15.2 11.1 21.2 8.1 12.7 22.0 22.8 8.8 13.2 24.9 15.7 17.6 8.6 4.1 14.8 20.6 17.7 15.5 17.1 12.0 16.3 8.2 19.3 9.7 20.4 23.6 10.2 12.8 12.4 21.4 15.8 16.6 10.9 12.3 17.1 1.2 1.7 1.4 2.0 1.1 1.9 1.4 1.8 2.6 1.5 2.0 2.0 1.3 1.2 2.7 2.6 3.1 0.8 1.0 7.3 6.2 3.7 6.8 7.9 5.3 8.4 7.8 7.0 6.3 8.3 5.5 10.5 6.4 10.3 1.3 14.7 13.5 14.8 9.3 8.6 24.5 12.4 7.2 29.3 25.8 13.8 7.3 43.8 11.9 18.0 198.7 5.9 24.7 1.0 16.3 16.2 17.6 24.5 11.1 4.9 23.6 9.8 13.0 20.9 18.6 12.0 19.8 18.9 33.0 15.2 30.3 5.6 22.9 6.1 20.4 10.7 2.8 12.5 11.0 0.0 2.8 20.4 9.2 22.6 4.5 4.3 31.6 51.8 11.7 11.8 20.4 91.7 21.7 11.5 25.5 13.1 18.8 9.6 9.4 10.1 13.7 17.6 9.3 13.9 21.4 29.4 18.7 PFKL ENSG00000141959 "Phosphofructokinase, liver type" P17858 21 44300051-44327376 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 273.7;Proximal enterocytes: 331.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030047 Approved Uncertain Nucleoli,Mitochondria NA NA 1100000 "Cluster 39: Non-specific - mRNA processing" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Mitochondria" "HPA030047: AB_10602815" "unprognostic (6.21e-3)" "unprognostic (2.93e-1)" "unprognostic (4.46e-2)" "unprognostic (1.23e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "unprognostic (6.98e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (4.41e-4)" "unprognostic (5.69e-2)" "unprognostic (5.40e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-1)" "unprognostic (2.49e-1)" "unprognostic (8.06e-2)" "unprognostic (3.01e-2)" 62.7 36.1 36.5 41.6 40.3 45.2 57.3 43.8 40.7 60.0 36.0 79.5 99.9 47.9 12.9 79.7 42.9 40.9 41.5 35.6 29.7 95.4 60.6 51.0 42.1 54.0 45.6 42.6 40.0 21.1 38.8 41.7 50.3 47.6 24.9 23.8 58.5 38.1 18.8 68.7 92.2 18.6 48.4 59.6 64.6 44.7 54.3 26.0 47.7 17.8 23.1 57.5 58.2 57.7 127.9 54.8 38.4 111.2 58.0 43.2 167.6 93.9 60.2 53.3 51.9 74.5 27.5 74.9 108.8 62.5 50.3 67.6 30.3 84.4 12.3 62.9 67.7 152.5 47.2 123.4 45.1 116.1 93.1 57.0 51.0 54.5 27.0 80.6 79.2 53.9 95.9 83.7 36.9 161.3 50.8 89.9 60.2 114.0 60.2 122.1 35.7 206.6 23.9 139.0 67.0 49.7 137.3 114.9 60.7 15.4 90.9 101.6 116.7 80.4 50.9 53.0 37.1 159.7 45.6 31.1 132.9 89.7 65.4 17.7 71.5 17.2 37.8 119.0 31.2 41.0 48.9 34.4 83.4 54.5 28.3 22.9 14.0 26.1 126.8 52.4 78.5 84.2 36.5 40.3 43.8 40.7 35.6 29.7 54.0 45.6 50.3 48.4 54.3 57.7 56.2 22.4 27.9 53.2 45.3 35.7 40.3 95.2 37.0 74.6 41.3 36.6 14.4 27.1 51.6 92.0 66.7 119.6 38.7 273.7 99.7 85.5 2.3 40.7 29.6 49.0 46.3 45.6 15.7 51.4 174.8 44.6 126.4 83.1 41.9 61.2 40.7 70.0 108.6 30.3 9.3 131.4 57.0 64.7 44.5 8.2 39.1 60.0 69.4 29.0 129.4 67.6 33.0 10.1 41.7 52.7 174.2 55.7 39.2 54.9 331.6 142.4 33.7 53.6 26.3 21.3 47.8 1.8 12.2 42.3 36.1 160.8 31.8 31.2 178.6 54.2 PGAP3 "CAB2, MGC9753, PER1, PERLD1, PP1498" ENSG00000161395 "Post-GPI attachment to proteins phospholipase 3" Q96FM1 17 39671122-39696797 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "OE19: 800.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016591 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA016591: AB_1855203" "unprognostic (1.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-3)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.61e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.57e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (9.05e-2)" "unprognostic (1.94e-2)" 10.5 11.9 17.0 5.6 17.2 5.0 12.9 14.0 19.6 14.6 16.2 18.6 14.9 11.3 18.3 25.8 15.9 13.4 14.8 17.5 16.7 20.6 35.6 12.1 7.4 14.9 15.4 13.5 27.1 22.7 14.9 11.8 14.6 18.5 13.7 7.1 25.1 11.7 8.3 21.0 17.1 6.1 14.7 12.3 16.6 9.1 16.5 4.8 27.1 4.5 7.5 12.2 13.7 15.5 3.7 9.6 7.7 7.0 7.9 8.1 7.9 4.3 10.1 6.7 6.1 5.4 23.8 4.2 19.7 8.3 2.2 12.6 2.4 2.9 3.1 8.6 7.7 5.2 6.0 9.3 10.6 12.9 12.8 14.9 15.0 3.1 6.8 7.6 2.2 1.9 4.9 9.6 6.1 8.7 2.9 11.7 7.6 800.4 2.1 3.2 4.7 12.1 10.7 12.0 7.1 4.7 11.9 134.0 6.9 0.8 11.4 12.4 3.4 7.2 7.6 3.5 3.3 8.5 2.0 1.4 8.1 4.9 8.1 2.6 7.2 4.6 15.2 11.6 8.3 8.1 10.6 12.5 5.7 7.7 10.1 10.1 2.0 10.4 4.3 3.9 5.4 7.3 17.0 17.2 14.0 19.6 17.5 16.7 14.9 15.4 14.6 14.7 16.5 15.5 6.5 3.2 14.9 7.8 3.7 3.8 3.3 5.6 3.4 12.6 9.1 7.0 7.7 14.3 10.1 14.7 8.4 8.1 5.3 20.3 1.9 7.6 0.1 3.5 4.5 5.0 8.4 3.0 9.0 11.1 6.5 5.1 9.2 5.7 8.9 6.8 4.6 9.0 4.4 13.5 6.3 15.3 8.2 5.1 2.8 0.1 3.1 3.7 1.8 2.8 1.9 7.5 4.1 9.0 6.1 6.3 13.9 1.5 2.8 3.7 22.9 3.4 4.9 22.1 0.0 5.0 3.3 0.7 2.4 8.1 2.8 10.4 4.9 5.8 13.3 3.1 PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2641.0;salivary gland: 1645.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7090.1;Intestinal goblet cells: 2361.1;Paneth cells: 3208.3;Proximal enterocytes: 1558.6;Undifferentiated cells: 4954.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "EFO-21: 36.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" NA NA 1300000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" 2.4 0.5 0.4 187.3 0.2 0.3 131.0 0.5 0.4 547.0 0.2 1693.4 2641.0 20.5 0.2 12.4 3.6 455.0 0.5 0.4 0.2 108.9 34.5 101.6 1.7 0.2 0.2 0.6 13.3 0.1 1.3 0.3 0.4 13.6 1222.6 0.1 1645.1 5.3 0.3 0.6 809.8 39.1 0.1 0.8 414.6 0.3 0.6 0.4 0.2 0.0 0.6 80.3 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 36.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 1.9 0.3 0.0 0.0 0.2 0.0 6.9 0.2 1.7 0.8 2.5 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.3 0.6 0.3 0.4 1.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.3 0.8 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.4 0.2 0.5 0.4 0.4 0.2 0.2 0.2 0.4 0.1 0.6 0.6 2.1 93.0 604.3 0.0 22.1 0.3 4.0 106.6 0.0 0.0 392.4 192.0 1.4 876.4 638.4 108.5 0.0 0.1 2.5 7090.1 17.6 92.5 0.0 65.9 14.6 5.4 426.4 2.7 0.0 64.5 0.0 4.7 482.1 120.1 52.0 0.0 1.8 28.0 0.4 0.0 0.0 2361.1 59.0 2.2 1.1 0.0 0.0 5.7 1.8 0.0 0.6 0.0 0.0 0.0 0.0 221.5 3208.3 0.0 0.7 53.9 1558.6 328.4 415.4 0.0 0.0 0.0 21.0 0.0 0.0 6.9 0.0 0.0 15.6 0.1 4954.6 761.3 PIGT ENSG00000124155 "Phosphatidylinositol glycan anchor biosynthesis class T" Q969N2 20 45416084-45456934 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.06e-2)" "unprognostic (4.60e-3)" "unprognostic (7.63e-2)" "unprognostic (6.00e-2)" "unprognostic (6.18e-3)" "unprognostic (6.68e-2)" "unprognostic (7.34e-3)" "unprognostic (1.17e-1)" "unprognostic (2.70e-2)" "unprognostic (3.32e-1)" "prognostic favorable (2.51e-4)" "unprognostic (5.48e-2)" "unprognostic (7.60e-2)" "unprognostic (9.21e-2)" "unprognostic (5.66e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-2)" 57.4 51.9 30.7 39.4 38.9 70.8 52.7 41.2 37.5 65.5 44.6 75.8 49.9 69.6 89.5 37.7 61.2 48.3 113.5 29.9 37.2 47.1 48.9 45.3 26.6 41.0 38.1 46.1 65.0 105.4 48.9 48.5 38.9 39.5 77.2 13.0 48.2 55.6 61.2 46.0 54.3 69.7 37.6 36.5 62.1 38.1 38.8 25.8 57.0 51.8 27.4 57.0 42.8 47.6 79.0 95.3 35.8 138.7 218.0 152.9 68.5 90.4 172.8 126.8 99.7 179.9 123.6 47.1 122.0 142.9 108.4 152.4 43.6 124.8 67.8 25.2 53.5 49.0 80.8 100.9 99.9 93.5 203.1 117.3 117.0 99.9 108.6 179.4 109.3 39.2 65.0 163.8 107.4 165.3 44.8 74.7 29.4 227.5 162.1 38.0 107.6 168.0 102.5 51.1 60.2 77.0 177.7 173.2 88.7 61.4 150.6 169.8 96.5 301.4 138.1 57.1 128.8 93.9 144.0 30.0 190.7 74.7 140.9 58.9 77.9 66.3 57.4 83.2 43.6 27.2 41.0 53.8 92.2 28.1 35.7 41.8 30.7 57.6 79.2 71.4 61.6 83.1 30.7 38.9 41.2 37.5 29.9 37.2 41.0 38.1 38.9 37.6 38.8 47.6 41.9 41.7 29.5 9.1 43.9 30.0 46.4 86.8 13.6 21.0 43.7 31.4 169.2 41.5 63.7 44.1 14.6 62.1 58.9 106.1 13.7 107.5 31.8 45.2 32.3 46.0 65.5 24.2 7.6 114.5 73.9 94.2 44.9 59.2 33.6 58.5 39.7 41.5 76.8 38.7 9.8 145.3 85.5 49.6 42.6 81.4 60.6 44.3 88.9 4.7 39.8 25.8 37.0 6.0 27.1 79.5 61.8 56.1 69.2 40.7 103.8 26.1 46.2 15.6 65.7 39.4 47.2 88.4 96.9 23.5 27.8 52.1 43.4 47.9 111.6 57.7 PIGZ "FLJ12768, MGC52163, SMP3" ENSG00000119227 "Phosphatidylinositol glycan anchor biosynthesis class Z" Q86VD9 3 196946356-196969060 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 39.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 205.1;Intestinal goblet cells: 61.3;Paneth cells: 129.7;Proximal enterocytes: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA058599, HPA059920" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA058599: AB_2683771, HPA059920: AB_2684162" "unprognostic (1.46e-1)" "unprognostic (3.18e-3)" "unprognostic (1.06e-2)" "unprognostic (3.31e-2)" "unprognostic (3.90e-2)" "unprognostic (8.16e-2)" "unprognostic (4.25e-3)" "unprognostic (4.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (5.44e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (1.02e-1)" "unprognostic (3.93e-2)" "unprognostic (8.38e-5)" "unprognostic (5.02e-3)" 6.7 1.6 8.2 2.0 8.5 1.0 5.4 8.6 9.6 4.3 4.4 39.1 1.6 3.4 0.7 4.2 3.4 2.0 6.9 8.1 9.2 2.1 2.6 3.7 1.1 7.6 8.6 0.8 2.7 3.0 4.1 1.0 10.0 6.1 16.7 3.1 4.7 2.6 7.4 4.7 11.7 2.7 5.3 1.9 4.6 1.6 8.6 1.2 1.9 3.2 0.5 10.4 4.6 7.7 1.8 1.2 0.7 2.8 7.7 3.7 0.7 2.6 7.3 2.0 1.6 1.7 1.5 0.3 5.1 5.9 1.3 3.0 0.1 0.4 0.5 0.5 0.3 0.8 0.6 6.5 3.6 0.0 2.9 3.7 5.6 0.3 0.9 2.2 2.4 4.7 0.2 2.2 1.9 3.2 0.3 1.5 0.1 2.2 0.9 0.4 0.1 0.6 3.0 3.3 1.1 1.2 3.7 0.3 1.5 0.3 7.2 2.6 6.0 1.6 0.4 4.7 0.9 1.0 0.1 0.1 0.4 1.1 0.6 0.0 0.3 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 8.2 8.5 8.6 9.6 8.1 9.2 7.6 8.6 10.0 5.3 8.6 7.7 8.9 0.0 1.1 20.5 1.7 7.8 9.1 3.8 6.8 7.1 22.6 33.9 8.0 1.5 2.8 9.2 2.1 0.0 2.8 205.1 5.9 2.3 2.1 5.1 3.0 5.5 13.8 3.0 31.3 3.6 0.0 5.0 1.5 6.5 5.7 0.3 12.1 10.3 1.8 15.2 21.9 61.3 10.2 4.4 3.4 5.0 4.1 2.2 8.8 5.6 4.1 4.6 2.1 12.5 2.7 3.2 129.7 6.4 1.9 7.4 50.0 5.4 2.7 7.0 0.0 7.7 6.5 1.2 0.2 11.5 5.1 0.1 1.7 0.0 44.4 14.7 PIK3C2B "C2-PI3K, PI3K-C2beta" ENSG00000133056 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta" O00750 1 204422628-204494724 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 70.3;RT4: 75.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030515, HPA050360" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA030515: AB_10670043, HPA050360: AB_2681104" "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-2)" "unprognostic (3.45e-1)" "unprognostic (2.19e-3)" "prognostic unfavorable (5.42e-4)" "unprognostic (3.35e-3)" "unprognostic (3.57e-3)" "unprognostic (2.72e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (5.36e-2)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "prognostic favorable (1.16e-4)" 12.0 3.6 10.4 15.2 23.6 5.0 9.7 8.5 23.3 7.4 0.0 15.8 14.4 8.4 4.8 12.9 6.5 8.0 10.6 11.2 18.8 10.2 4.9 17.2 23.4 19.2 20.4 3.0 5.2 3.2 3.3 12.8 17.1 6.2 12.9 2.9 7.2 5.4 20.9 21.2 14.9 9.9 7.3 13.6 18.9 1.9 28.0 22.3 8.1 10.8 22.1 10.9 10.7 44.2 7.5 14.8 12.9 11.9 7.4 0.6 70.3 0.9 2.9 2.8 2.1 8.8 19.2 12.7 2.7 1.7 2.5 18.3 7.7 5.2 1.1 7.7 2.1 0.3 30.1 3.3 0.4 4.5 9.3 0.9 5.4 0.7 0.4 1.1 19.1 12.6 4.7 8.3 0.2 16.7 15.4 12.8 11.8 29.3 9.3 16.6 3.3 2.4 3.5 75.6 14.1 7.8 26.0 35.9 8.4 4.7 16.1 2.4 0.7 0.4 4.5 1.3 0.2 8.9 2.6 16.4 0.5 6.7 1.9 0.0 0.1 0.0 0.5 0.0 0.5 1.5 0.6 0.4 0.1 3.2 0.3 0.3 0.2 0.8 0.0 0.0 1.2 0.2 10.4 23.6 8.5 23.3 11.2 18.8 19.2 20.4 17.1 7.3 28.0 44.2 26.7 0.0 12.2 16.0 15.3 3.8 2.1 7.9 1.2 16.6 5.3 4.4 6.9 5.7 6.9 3.7 0.0 4.4 3.3 29.2 0.0 1.8 0.6 2.0 2.5 26.1 9.6 0.0 14.3 3.4 4.4 4.5 28.5 2.4 32.4 8.5 31.1 5.5 4.2 15.2 22.8 23.8 2.0 1.6 5.1 0.7 1.2 2.9 3.6 27.2 2.3 2.7 4.1 23.6 111.5 4.7 14.5 7.5 4.9 2.4 14.6 2.1 9.1 1.0 0.0 7.7 3.3 0.1 1.5 8.1 8.0 2.2 5.0 9.4 15.5 13.8 PIK3R2 "p85, P85B" ENSG00000105647 "Phosphoinositide-3-kinase regulatory subunit 2" O00459 19 18153163-18170532 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 14.4;Undifferentiated cells: 16.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" HPA069291 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA069291: AB_2686109" "unprognostic (2.50e-1)" "unprognostic (1.90e-3)" "unprognostic (1.68e-2)" "unprognostic (1.87e-1)" "unprognostic (2.00e-2)" "unprognostic (9.65e-3)" "unprognostic (1.69e-3)" "unprognostic (2.36e-3)" "unprognostic (9.24e-2)" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (3.36e-1)" "unprognostic (1.69e-2)" "unprognostic (2.02e-1)" "unprognostic (6.35e-3)" "unprognostic (8.63e-2)" "unprognostic (2.00e-2)" 7.2 25.6 26.2 6.9 22.9 9.7 7.6 1.1 41.5 17.6 2.0 13.4 20.5 17.5 12.0 26.0 16.7 12.3 12.8 41.0 6.7 9.5 10.5 9.1 5.2 4.4 7.1 21.5 11.0 20.8 21.5 8.7 4.9 15.5 9.6 7.9 15.0 10.4 12.4 26.3 16.7 9.8 4.7 8.7 15.1 11.5 9.4 11.6 10.5 9.9 6.2 15.3 15.3 16.4 39.1 18.0 25.4 36.8 35.3 36.6 40.5 29.4 38.3 21.6 16.6 18.3 20.4 28.0 48.8 41.9 17.5 28.7 15.6 33.2 11.3 25.0 65.5 10.8 21.3 44.0 29.7 24.6 13.4 45.7 36.4 15.0 21.5 36.8 6.6 11.9 33.6 10.8 30.3 57.0 21.5 17.0 32.9 35.8 48.5 19.6 33.4 23.5 37.7 22.8 63.0 68.0 27.1 28.5 28.9 16.0 19.1 15.8 11.4 40.9 20.8 49.2 27.5 22.9 26.4 10.9 33.9 39.4 26.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 26.2 22.9 1.1 41.5 41.0 6.7 4.4 7.1 4.9 4.7 9.4 16.4 1.0 6.4 1.1 7.2 0.8 1.9 1.3 1.0 1.8 6.3 3.6 3.2 1.5 2.8 1.0 3.7 4.2 1.7 0.8 6.9 0.0 6.0 0.3 1.3 1.7 0.8 6.1 7.4 11.7 6.2 2.9 1.7 1.1 0.8 2.5 1.4 1.4 1.3 2.2 10.1 11.2 10.5 0.0 4.7 1.0 0.0 1.8 1.7 0.0 3.7 1.6 5.7 0.0 10.6 9.2 6.4 7.0 1.9 0.9 1.1 14.4 1.1 0.5 4.3 0.0 1.4 1.4 0.5 2.1 1.3 2.3 1.2 0.9 3.2 16.4 0.6 PINK1 "BRPK, PARK6" ENSG00000158828 "PTEN induced kinase 1" Q9BXM7 1 20633458-20651511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 384.4;tongue: 392.3" "Cell type enhanced" "Detected in many" "Late spermatids: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001931, CAB026191" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026191: , HPA001931: AB_1079620" "unprognostic (3.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-2)" "unprognostic (3.36e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-3)" "unprognostic (3.34e-2)" "unprognostic (2.54e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" 50.7 127.2 119.3 13.7 103.4 13.0 41.9 104.6 110.9 37.9 73.0 62.3 32.3 43.9 18.8 48.8 34.4 23.5 153.4 106.6 107.0 56.8 76.8 30.1 10.8 118.5 127.8 30.1 52.7 66.5 33.4 21.3 118.3 37.1 15.0 29.4 55.0 29.7 384.4 55.3 35.2 20.0 124.9 27.9 46.7 94.8 132.1 12.3 41.6 392.3 8.3 47.4 42.7 95.0 49.9 22.2 10.3 29.6 34.6 32.8 10.7 68.2 67.9 32.4 56.1 7.7 39.3 11.7 52.6 69.9 75.4 22.5 15.0 36.2 16.0 14.0 56.8 5.9 60.3 12.1 26.8 6.3 17.7 30.8 38.5 40.6 13.9 36.2 21.3 10.7 14.5 14.5 23.6 21.2 9.2 14.1 4.6 12.9 72.2 7.9 18.0 9.4 20.1 11.5 37.8 14.8 74.4 24.2 20.8 12.3 8.0 21.6 32.6 29.1 14.9 49.2 9.7 16.7 3.6 5.4 63.1 17.9 14.0 3.6 1.6 3.7 0.8 1.1 1.0 0.2 0.7 1.1 0.5 1.4 0.5 0.8 8.1 0.6 3.9 1.0 1.5 0.6 119.3 103.4 104.6 110.9 106.6 107.0 118.5 127.8 118.3 124.9 132.1 95.0 38.7 22.4 19.2 16.3 9.1 15.7 36.0 7.9 10.8 50.1 31.5 24.4 1.1 37.1 9.2 44.1 37.5 26.3 9.2 107.4 80.3 24.0 77.7 22.3 16.1 48.5 20.0 56.0 27.2 28.0 31.8 27.4 12.2 26.4 0.0 36.7 84.3 110.5 23.7 28.6 24.4 30.2 12.2 27.1 16.3 151.4 35.4 22.7 21.4 25.3 10.1 69.7 12.3 8.5 14.3 56.6 67.9 56.8 27.0 67.5 66.9 109.2 7.6 69.0 85.5 30.9 32.2 120.8 24.6 19.3 24.0 34.2 10.6 34.2 24.4 47.9 PITPNM1 "DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1" ENSG00000110697 "Phosphatidylinositol transfer protein membrane associated 1" O00562 11 67491768-67506263 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Distal enterocytes: 69.9;Endometrial ciliated cells: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 91.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060227 Approved Supported Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA060227: AB_2684226" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" "unprognostic (1.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.83e-2)" "unprognostic (8.68e-2)" "unprognostic (8.16e-2)" "unprognostic (4.55e-2)" "unprognostic (1.77e-1)" "unprognostic (2.26e-2)" "unprognostic (4.61e-1)" "unprognostic (3.27e-2)" "unprognostic (2.32e-2)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (4.62e-2)" "unprognostic (5.69e-2)" 10.6 24.5 19.6 24.3 12.6 26.8 6.4 6.1 23.2 10.7 13.9 14.4 18.7 9.3 2.4 19.5 23.1 9.0 22.3 13.3 23.8 37.8 11.0 16.3 27.6 14.2 31.0 4.0 9.8 10.3 26.7 8.0 13.5 10.4 7.5 40.7 8.7 10.3 6.9 5.0 21.1 5.9 2.3 21.6 16.0 8.8 51.5 17.4 15.7 18.4 17.2 16.2 9.3 5.5 12.7 31.2 18.8 13.9 20.3 12.1 30.5 12.2 21.5 14.8 8.4 28.5 22.6 12.5 28.7 17.5 28.4 32.4 14.5 27.0 4.8 91.0 6.0 17.0 55.8 10.8 16.0 19.4 35.3 15.0 17.0 22.4 14.7 27.4 17.9 18.7 13.2 11.0 12.5 19.1 33.2 45.6 19.3 35.9 13.5 23.7 6.0 17.3 24.4 25.1 18.1 11.5 27.3 37.6 29.6 9.0 7.4 16.9 17.7 26.5 20.1 16.9 8.9 16.0 8.3 11.2 37.1 22.7 10.6 0.0 1.4 0.9 1.1 3.3 1.0 0.7 0.8 1.0 1.0 0.5 0.3 0.8 1.4 0.1 2.7 0.4 0.7 1.1 19.6 12.6 6.1 23.2 13.3 23.8 14.2 31.0 13.5 2.3 51.5 5.5 7.5 3.2 5.8 2.0 10.8 8.2 6.3 9.3 13.6 45.7 5.4 5.2 8.4 5.7 9.7 20.2 64.6 4.6 10.6 69.9 3.9 11.3 6.1 63.3 16.5 4.9 11.4 0.4 5.1 9.3 8.9 4.2 34.7 24.6 2.5 7.1 3.3 3.4 8.4 38.7 6.6 16.8 10.2 13.2 14.0 17.0 2.1 15.2 3.6 10.3 13.5 20.7 3.1 0.5 0.5 15.9 32.7 1.2 7.5 9.8 39.0 18.9 37.8 53.7 0.0 6.3 9.8 1.4 5.5 11.2 3.3 15.2 14.9 1.4 24.0 19.4 PKIB PRKACN2 ENSG00000135549 "CAMP-dependent protein kinase inhibitor beta" Q9C010 6 122471917-122726373 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.4;intestine: 90.8;parathyroid gland: 63.7;placenta: 60.4" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 542.7;Distal enterocytes: 750.2;Extravillous trophoblasts: 420.5;Langerhans cells: 251.9;Late spermatids: 251.1;Paneth cells: 355.4;Proximal enterocytes: 255.0;Syncytiotrophoblasts: 959.8" "Cancer enhanced" "Detected in all" "breast cancer: 16.3" "Region enriched" "Detected in all" 5 "cerebellum: 70.4" "Immune cell enriched" "Detected in some" 11 "myeloid DC: 34.8" "Lineage enriched" "Detected in many" 11 "dendritic cells: 34.8" "Cell line enhanced" "Detected in many" "AF22: 71.8;MCF7: 84.9;OE19: 91.2;PC-3: 112.5;RPTEC TERT1: 187.1;SCLC-21H: 157.7" "Region enhanced" "Detected in all" "cerebellum: 63.0" "Region enhanced" "Detected in all" "cerebellum: 45.0" HPA030156 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA030156: AB_10602816" "unprognostic (1.59e-2)" "unprognostic (1.82e-1)" "unprognostic (1.99e-2)" "unprognostic (1.57e-3)" "unprognostic (1.39e-1)" "unprognostic (9.45e-2)" "prognostic unfavorable (4.72e-7)" "unprognostic (1.94e-2)" "unprognostic (5.88e-2)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "unprognostic (3.58e-2)" "prognostic favorable (2.47e-7)" "unprognostic (1.82e-1)" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" 2.2 5.8 4.4 9.0 3.9 0.2 23.3 70.4 5.2 4.9 3.4 90.8 15.5 3.4 3.4 5.2 5.5 5.7 0.5 5.9 6.9 2.8 8.2 4.1 2.2 13.9 7.4 0.8 6.3 63.7 22.1 60.4 14.6 6.2 62.4 56.1 8.5 2.4 0.7 9.1 28.3 3.9 3.9 3.2 34.4 4.2 6.8 3.7 1.1 0.6 4.1 5.4 1.2 5.0 0.1 2.8 71.8 0.3 0.6 0.3 62.4 0.0 0.8 0.3 1.2 0.4 3.0 0.0 0.4 0.0 3.8 0.3 0.0 1.5 0.8 0.4 3.7 1.2 3.9 1.7 0.2 0.0 12.3 0.3 1.2 1.2 15.3 34.0 0.3 0.5 22.3 0.4 0.2 84.9 0.3 0.4 29.6 91.2 112.5 0.6 10.8 0.4 187.1 10.6 157.7 0.2 0.0 17.1 2.0 39.4 12.0 1.8 5.7 0.2 47.3 0.2 6.2 0.2 0.3 0.2 46.7 1.5 0.4 0.0 0.6 0.0 0.0 3.2 0.7 0.0 0.0 0.0 34.8 0.1 0.4 0.1 0.1 1.9 0.3 0.5 0.4 0.7 4.4 3.9 70.4 5.2 5.9 6.9 13.9 7.4 14.6 3.9 6.8 5.0 3.0 3.2 3.9 17.0 4.6 19.8 2.3 2.5 2.8 23.6 94.8 53.3 0.3 2.8 10.2 1.8 4.2 542.7 0.9 750.2 19.6 22.6 106.0 5.3 1.6 3.9 98.0 4.0 5.5 35.8 420.5 6.9 52.0 5.5 38.7 0.3 1.1 3.8 53.1 6.7 15.5 94.9 14.2 75.5 251.9 251.1 1.2 51.2 44.4 9.4 25.5 15.2 0.0 6.0 8.5 50.4 355.4 0.4 1.2 13.8 255.0 26.9 58.3 54.8 6.6 0.3 2.7 3.3 5.8 12.4 17.0 959.8 3.5 0.2 92.9 8.3 PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 345.0;Extravillous trophoblasts: 176.8;Paneth cells: 248.9;Proximal enterocytes: 195.6;Undifferentiated cells: 142.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 151.3;CAPAN-2: 102.6;HaCaT: 199.1;hTCEpi: 126.9;MCF7: 94.9;SK-BR-3: 148.0" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" 1.1 0.1 0.3 3.7 0.2 0.0 9.1 0.2 0.6 50.2 0.1 34.3 31.1 1.4 4.7 294.4 7.5 4.9 0.8 0.3 0.3 4.2 0.8 9.7 0.1 0.6 0.2 0.3 27.4 9.1 15.8 10.9 0.6 19.8 10.2 0.0 52.8 5.0 1.0 223.0 28.6 0.5 0.2 0.2 29.1 0.7 0.3 2.5 12.8 0.1 8.8 9.2 104.3 0.3 151.3 28.8 0.0 0.6 0.1 0.2 60.3 1.2 1.0 3.1 1.6 59.2 102.6 0.1 6.0 1.1 6.4 199.1 0.0 75.1 0.5 0.1 36.9 0.1 18.0 41.7 0.6 0.0 0.3 0.5 126.9 0.5 30.8 0.5 0.5 0.0 45.3 0.9 0.4 94.9 0.5 0.2 0.3 75.6 49.1 0.8 0.3 0.6 1.6 29.9 41.1 0.7 42.7 148.0 0.2 1.8 53.8 0.4 5.4 1.0 5.2 2.7 0.8 0.2 0.4 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.6 0.3 0.3 0.6 0.2 0.6 0.2 0.3 0.3 0.2 16.0 13.0 0.0 1.1 72.1 52.0 56.1 54.7 0.2 27.7 26.5 1.1 11.5 36.8 12.9 0.0 133.8 0.4 345.0 0.0 83.8 0.0 16.1 1.8 1.8 21.7 0.0 0.2 62.9 176.8 2.3 91.3 27.4 13.4 0.4 0.0 0.3 13.2 0.0 0.0 95.1 36.7 0.3 6.5 0.4 0.9 0.9 1.8 0.0 2.0 0.6 0.0 0.0 0.0 140.2 248.9 0.0 0.2 63.5 195.6 0.9 17.9 0.2 0.0 0.0 2.8 0.2 1.7 114.1 88.7 109.7 1.6 0.0 142.9 60.4 PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672548-14694308 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 27.3;pancreas: 10.5;stomach 1: 41.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 280.1;Exocrine glandular cells: 116.3;Gastric mucus-secreting cells: 116.2;Intestinal goblet cells: 137.7;Paneth cells: 225.3" "Cancer enhanced" "Detected in many" "stomach cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.6;CAPAN-2: 6.4;HaCaT: 2.2;MCF7: 2.3;OE19: 5.9;SK-BR-3: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041893 Uncertain "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041893: AB_10794495" "unprognostic (8.44e-3)" "unprognostic (2.37e-1)" "unprognostic (6.72e-2)" "prognostic favorable (5.74e-5)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (5.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-2)" "unprognostic (9.97e-3)" 0.0 0.2 0.1 2.4 0.1 0.1 0.1 0.1 0.2 1.3 0.1 27.3 7.6 0.1 0.0 0.2 4.5 3.4 0.0 0.1 0.1 0.1 0.0 4.7 0.2 0.1 0.1 0.0 10.5 0.0 0.0 0.3 0.1 0.4 23.6 0.0 0.1 0.0 0.0 0.0 7.0 0.6 0.1 0.0 41.9 2.2 0.1 0.0 0.0 0.0 0.3 4.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.5 6.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 5.9 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 3.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 35.3 23.1 0.7 0.3 0.0 0.9 3.7 0.6 0.0 0.7 0.5 0.1 5.7 17.9 1.8 0.0 0.6 0.1 280.1 0.0 2.6 0.3 25.1 3.5 0.2 12.7 0.0 0.5 116.3 56.7 0.1 116.2 45.7 0.0 0.4 0.0 0.0 0.9 0.0 0.3 137.7 24.4 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 20.5 225.3 0.0 0.7 1.3 16.1 0.0 60.1 0.0 0.0 0.0 2.0 1.1 1.2 1.7 0.0 0.5 0.5 0.0 57.3 14.6 PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 365.9;esophagus: 92.0;intestine: 236.0;lymphoid tissue: 155.1;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1118.2;Distal enterocytes: 1514.4;Extravillous trophoblasts: 572.2;NK-cells: 1103.0;Paneth cells: 865.7;Respiratory ciliated cells: 549.6" "Cancer enhanced" "Detected in many" "stomach cancer: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2310.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 183.2;CAPAN-2: 510.7;HL-60: 329.1;NB-4: 160.1;RPMI-8226: 238.2;THP-1: 187.8;U-937: 149.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA040465: AB_10794875, HPA077912: AB_2686870" "unprognostic (6.82e-5)" "prognostic favorable (3.03e-4)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.14e-1)" "unprognostic (1.94e-3)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (7.44e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-7)" "unprognostic (3.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" 9.2 2.0 1.8 81.3 2.0 365.9 3.8 2.8 2.4 32.8 1.4 236.0 78.9 2.7 1.2 92.0 18.7 6.5 2.8 1.5 1.7 2.6 35.4 41.2 93.8 7.8 2.7 1.0 1.6 0.5 2.0 33.7 5.5 3.7 163.3 1.1 6.6 2.3 2.0 1.0 88.5 18.5 2.3 155.1 117.5 0.8 2.4 40.5 2.6 0.8 137.5 11.0 5.8 3.7 183.2 1.3 0.5 1.1 0.0 0.2 28.6 4.6 1.1 11.1 13.7 3.5 510.7 30.7 1.5 52.3 17.0 18.7 3.2 1.4 41.6 0.2 0.6 0.8 33.4 15.2 1.8 329.1 1.7 0.9 3.6 1.8 2.4 0.3 0.8 16.0 0.4 2.6 29.5 0.8 62.6 160.1 1.0 14.4 0.9 8.0 10.6 238.2 0.9 5.4 25.8 0.5 1.2 29.1 0.6 9.0 1.6 187.8 1.3 1.1 31.7 0.9 0.9 1.8 0.4 81.7 2.3 149.7 0.2 49.2 139.2 95.9 392.1 635.8 299.4 523.8 185.1 229.2 129.5 481.1 225.9 263.4 29.7 1053.3 358.9 2310.7 13.8 577.1 1.8 2.0 2.8 2.4 1.5 1.7 7.8 2.7 5.5 2.3 2.4 3.7 4.3 195.5 39.2 0.3 247.4 0.4 1.7 77.3 0.0 0.3 0.9 1.4 0.5 2.8 119.1 0.0 0.0 18.5 1118.2 1514.4 0.0 0.3 0.5 45.6 1.1 95.0 86.8 58.4 0.1 3.6 572.2 3.1 119.8 2.9 26.6 0.6 141.0 8.4 21.7 1.7 0.1 231.2 67.1 384.5 7.4 0.6 0.0 213.3 7.2 1.0 157.3 1.2 1103.0 0.0 0.2 99.0 865.7 0.0 35.7 1.1 374.4 1.4 549.6 0.3 6.6 0.7 8.0 0.2 0.8 10.1 0.1 14.2 150.6 0.1 104.2 9.0 PLCD1 ENSG00000187091 "Phospholipase C delta 1" P51178 3 38007496-38029642 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 89.5;Theca cells: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 25.3;fHDF/TERT166: 26.3;hTCEpi: 31.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009913, HPA020107, HPA021677" Approved Approved Microtubules NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "CAB009913: AB_2163388, HPA020107: AB_1855318, HPA021677: AB_1855319" "unprognostic (1.75e-3)" "unprognostic (1.01e-2)" "unprognostic (4.29e-2)" "unprognostic (1.45e-2)" "unprognostic (3.44e-1)" "unprognostic (9.67e-3)" "unprognostic (1.55e-1)" "unprognostic (7.25e-3)" "unprognostic (3.95e-1)" "unprognostic (1.45e-1)" "unprognostic (2.80e-1)" "unprognostic (2.24e-1)" "prognostic favorable (9.25e-11)" "unprognostic (1.50e-1)" "unprognostic (7.71e-2)" "unprognostic (2.93e-1)" "unprognostic (7.88e-2)" 14.8 12.9 14.3 4.6 16.1 4.3 10.6 15.4 15.6 15.9 9.7 15.7 4.9 11.5 4.2 26.2 9.8 5.6 7.2 12.8 19.0 10.1 5.4 11.3 6.6 20.3 18.5 12.7 6.0 3.9 9.3 3.8 19.6 9.1 10.1 2.8 13.0 8.8 2.9 18.5 8.3 5.6 19.4 7.2 8.3 32.6 16.9 9.1 8.3 4.1 6.6 15.7 19.0 21.9 1.0 2.7 9.4 2.6 25.3 22.2 2.8 2.8 11.1 4.2 6.4 1.0 2.3 0.6 1.4 26.3 2.9 15.0 4.8 3.0 1.3 3.9 1.2 0.5 1.7 4.7 14.7 0.0 1.6 18.0 31.6 12.9 1.7 9.4 8.2 2.2 16.3 1.3 9.6 1.2 2.2 1.1 2.4 5.5 2.7 0.9 1.3 3.6 5.1 5.0 0.1 2.6 0.8 12.4 3.2 3.1 2.7 1.2 4.4 2.5 6.3 6.7 0.1 5.2 2.2 0.6 6.4 0.1 1.3 14.6 2.7 0.2 13.0 3.7 15.2 1.3 16.9 12.8 3.8 0.6 10.1 7.9 9.9 5.9 2.2 2.0 16.6 7.4 14.3 16.1 15.4 15.6 12.8 19.0 20.3 18.5 19.6 19.4 16.9 21.9 5.2 3.2 7.5 22.9 3.6 2.8 12.4 9.6 8.0 0.9 5.4 6.1 4.7 8.6 7.3 9.2 2.1 1.8 4.2 89.5 3.9 11.4 1.7 3.3 11.3 8.1 4.9 3.6 1.9 3.0 5.1 10.2 6.6 3.8 4.5 3.6 20.0 4.1 4.0 3.3 2.3 28.3 10.2 3.8 14.5 3.6 12.8 4.3 1.8 3.7 3.4 13.3 1.0 7.1 2.2 4.1 34.7 14.3 5.9 13.2 10.0 5.8 6.2 1.7 6.6 5.4 7.2 3.1 3.7 12.6 5.8 0.8 7.4 53.4 11.3 14.7 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108959-45133354 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 195.8;Paneth cells: 104.7;Urothelial cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA025711: AB_1855320, HPA053665: AB_2732580" "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favorable (4.28e-4)" "unprognostic (3.34e-3)" 13.5 34.3 42.2 5.1 49.7 2.0 11.7 50.5 36.0 12.4 27.9 34.2 2.5 13.2 1.5 14.7 10.1 6.4 34.1 33.8 42.5 9.6 1.4 7.7 1.0 69.8 50.5 18.9 2.7 1.3 7.6 5.8 46.4 13.0 15.3 14.4 10.8 5.4 85.7 20.6 6.5 5.1 62.8 2.0 21.0 10.8 59.4 0.9 5.3 56.5 1.5 30.4 11.9 54.0 23.1 56.2 4.1 8.1 5.9 12.8 28.0 12.3 27.3 11.2 10.5 13.7 40.9 0.8 43.5 29.0 9.2 51.9 6.3 53.1 4.4 11.6 21.0 0.9 62.6 18.1 30.3 1.3 3.2 13.7 21.0 10.4 13.7 28.5 7.0 2.5 5.0 1.7 12.1 36.2 3.7 5.4 4.9 109.9 55.0 8.1 9.2 1.5 35.8 45.1 1.1 7.2 13.3 22.1 12.5 8.5 47.0 2.5 14.3 6.9 37.9 9.3 14.8 2.1 2.6 1.8 11.4 1.5 5.7 0.7 0.3 0.5 0.1 0.3 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.2 0.0 0.1 0.1 0.1 42.2 49.7 50.5 36.0 33.8 42.5 69.8 50.5 46.4 62.8 59.4 54.0 8.7 12.8 1.3 22.9 1.0 7.6 16.3 12.2 21.1 29.8 6.8 9.3 26.9 14.3 4.9 7.3 25.0 3.9 0.9 195.8 1.9 6.7 15.8 3.3 12.7 9.0 4.9 0.0 1.3 3.5 13.1 10.6 29.6 9.6 1.3 6.5 10.4 0.7 1.6 6.7 3.7 15.1 4.1 1.4 1.9 5.5 19.9 1.6 3.6 1.0 1.2 8.9 0.0 0.0 0.1 30.0 104.7 33.1 1.1 28.7 4.2 2.0 2.7 40.0 6.6 16.8 4.9 2.3 7.6 3.8 5.7 7.3 1.1 7.0 46.2 88.6 PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 34.7;Distal enterocytes: 34.2;Gastric mucus-secreting cells: 33.1;Paneth cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 110.4;HEL: 172.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007721: AB_1079630" "unprognostic (2.73e-2)" "unprognostic (5.67e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.80e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (4.80e-2)" "unprognostic (7.25e-2)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.82e-14)" "unprognostic (6.01e-2)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" 14.7 4.1 4.6 9.4 8.8 32.9 9.7 13.0 19.2 10.0 0.0 8.2 8.6 5.6 1.4 17.5 9.1 8.8 5.6 4.4 0.0 5.7 10.1 7.4 17.3 3.4 1.5 12.8 7.5 3.2 7.7 7.8 4.4 7.5 5.7 6.0 11.4 3.7 8.4 18.7 12.5 2.7 0.5 17.5 26.9 6.7 4.0 8.9 10.4 2.7 9.0 6.1 9.7 13.4 28.4 110.4 25.7 38.8 5.0 3.9 20.4 24.4 2.9 12.8 12.4 40.6 29.1 34.8 17.9 10.7 19.0 8.5 6.3 15.9 6.7 21.2 46.2 172.6 36.1 59.7 15.6 17.4 63.1 20.1 1.9 47.0 4.9 8.6 9.7 57.2 44.0 18.7 9.2 8.2 52.3 24.2 57.8 7.1 19.2 29.1 13.3 53.9 3.9 12.9 25.9 15.0 24.6 14.4 21.1 17.5 27.6 22.0 7.2 17.1 28.2 18.5 26.9 6.3 17.9 86.4 11.0 44.4 18.2 3.7 2.7 5.4 1.9 6.0 2.7 1.6 1.4 2.4 2.0 5.6 1.8 1.9 3.3 1.2 9.0 2.1 3.2 2.3 4.6 8.8 13.0 19.2 4.4 0.0 3.4 1.5 4.4 0.5 4.0 13.4 15.8 9.6 34.7 5.5 4.1 6.9 13.6 3.9 2.2 7.4 4.7 3.6 6.5 10.0 2.8 0.0 2.1 10.1 4.9 34.2 0.0 6.3 0.9 1.6 3.4 6.1 3.0 9.9 5.3 1.8 11.3 6.1 33.1 3.2 3.8 32.1 4.6 6.9 5.5 8.4 6.1 11.2 0.0 7.3 9.8 0.9 2.5 11.9 0.0 5.6 3.7 2.3 9.2 0.5 5.7 18.8 40.9 3.8 2.7 5.3 3.0 1.7 1.3 7.1 13.1 6.5 7.9 8.4 15.9 4.2 8.7 27.0 3.8 2.8 9.4 8.0 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 256.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 384.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 41.8 30.9 44.2 22.6 25.4 43.2 37.9 20.4 39.7 57.4 6.7 58.0 21.1 55.2 8.5 59.7 47.9 22.8 78.9 42.2 31.0 30.0 31.3 49.2 22.1 48.5 28.6 47.1 27.6 8.1 33.0 18.3 30.8 49.5 13.0 3.9 42.9 19.8 256.5 83.1 53.8 27.7 28.8 46.1 49.1 15.3 43.2 14.4 25.7 74.7 15.8 56.5 55.7 25.9 92.6 247.3 15.1 20.3 31.6 66.9 62.8 125.9 49.3 32.3 18.7 39.2 88.5 8.9 82.9 179.7 54.6 98.9 10.3 162.6 13.3 58.7 10.0 24.9 268.0 34.0 54.0 9.6 26.1 71.8 40.7 84.6 164.2 28.3 43.0 7.6 16.2 25.9 39.7 175.3 5.1 19.8 12.2 29.4 384.8 1.8 46.2 24.6 67.7 147.7 16.6 16.8 217.4 50.0 21.1 21.7 55.7 12.4 125.7 117.8 217.3 110.6 155.1 4.7 3.7 6.3 106.9 15.2 176.2 0.0 2.0 0.1 0.6 1.7 1.3 0.6 1.2 0.9 1.6 0.6 0.8 0.5 0.4 0.3 1.2 1.3 1.4 2.0 44.2 25.4 20.4 39.7 42.2 31.0 48.5 28.6 30.8 28.8 43.2 25.9 83.8 28.9 15.6 78.0 27.0 108.0 53.1 62.9 50.7 15.8 29.4 27.9 39.3 31.5 42.9 40.5 25.0 34.4 27.1 257.8 0.0 39.3 1.4 39.4 52.6 68.2 32.2 11.8 47.3 20.2 32.1 45.7 170.2 57.3 8.2 14.4 63.1 69.0 35.2 30.3 36.5 79.9 10.2 67.5 100.4 5.0 44.4 61.2 33.8 27.2 54.9 11.2 15.5 14.6 3.4 157.8 194.1 74.9 39.3 144.9 124.9 4.6 50.3 10.8 6.6 42.1 61.5 1.2 7.1 72.2 76.7 69.0 35.0 18.8 61.6 121.0 PLEKHA6 "KIAA0969, PEPP3" ENSG00000143850 "Pleckstrin homology domain containing A6" Q9Y2H5 1 204218853-204377665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Distal enterocytes: 66.6;Excitatory neurons: 102.6;Inhibitory neurons: 62.5;Oligodendrocyte precursor cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 60.3;BEWO: 94.6;CAPAN-2: 79.2;OE19: 80.9;RT4: 66.4;SK-BR-3: 58.4;T-47d: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028152, HPA028157, HPA054311" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Vesicles "HPA028152: AB_10601048, HPA028157: , HPA054311: AB_2682446" "unprognostic (9.81e-3)" "unprognostic (3.05e-1)" "unprognostic (1.59e-2)" "unprognostic (3.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (1.38e-2)" "unprognostic (9.01e-2)" "unprognostic (3.32e-1)" "unprognostic (9.60e-3)" "unprognostic (1.53e-1)" "unprognostic (5.02e-3)" "unprognostic (1.23e-1)" "unprognostic (8.22e-2)" "unprognostic (5.17e-2)" "prognostic favorable (3.57e-4)" 5.1 6.6 20.4 6.0 21.6 0.4 13.7 20.9 34.4 4.1 9.1 32.2 25.5 4.8 12.9 17.2 9.3 13.2 20.8 19.6 18.7 27.4 27.5 3.2 0.6 23.1 24.3 4.6 10.2 5.7 31.1 8.8 23.3 13.8 29.3 11.4 9.0 13.9 6.0 4.0 29.5 3.8 17.9 3.1 39.7 5.4 34.6 1.0 4.0 2.4 2.4 12.7 7.5 24.1 60.3 36.8 23.7 0.1 0.3 0.6 94.6 2.1 6.6 0.2 0.3 17.8 79.2 0.3 17.3 1.4 0.3 6.7 0.3 6.5 0.3 0.2 3.8 0.2 15.2 25.7 3.5 0.0 0.1 1.0 19.6 0.0 5.0 7.2 10.4 0.8 0.1 0.2 23.9 26.7 0.1 0.1 7.4 80.9 44.6 0.0 0.2 0.1 23.0 66.4 4.8 48.4 26.6 58.4 0.4 4.9 55.3 0.3 0.7 0.0 1.0 0.3 0.5 0.2 0.0 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.6 20.9 34.4 19.6 18.7 23.1 24.3 23.3 17.9 34.6 24.1 0.2 0.0 10.9 111.0 0.3 0.1 4.2 1.9 0.6 41.6 15.7 8.1 16.6 37.1 4.5 9.2 20.9 6.6 0.5 66.6 3.9 8.4 10.4 4.0 1.3 1.2 16.8 2.7 102.6 5.1 2.4 9.0 40.8 6.2 0.0 0.3 5.0 21.4 0.8 18.5 62.5 32.7 4.1 0.6 0.7 4.0 5.3 0.7 0.0 15.0 0.1 1.2 0.0 85.5 41.8 13.3 33.2 3.8 0.1 6.9 15.2 11.7 7.2 7.1 0.0 26.4 1.1 0.6 0.2 1.4 0.6 21.6 0.6 0.1 34.5 13.7 PLEKHG3 "ARHGEF43, KIAA0599" ENSG00000126822 "Pleckstrin homology and RhoGEF domain containing G3" A1L390 14 64704102-64750249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 179.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 24.0;NK-cells: 9.4;T-cells: 16.2" "Cell line enhanced" "Detected in many" "A-431: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063455, HPA065323, HPA073702, HPA074734" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Centrosome,Cytosol" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Cytokinetic bridge, Centrosome" "HPA063455: AB_2685015, HPA065323: AB_2685467, HPA073702: AB_2732238, HPA074734: AB_2732265" "unprognostic (8.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.38e-2)" "unprognostic (4.04e-2)" "unprognostic (2.18e-1)" "unprognostic (7.22e-2)" "unprognostic (7.21e-2)" "unprognostic (5.53e-3)" "unprognostic (1.49e-1)" "unprognostic (3.34e-3)" "unprognostic (3.63e-1)" "unprognostic (3.54e-2)" "prognostic favorable (7.39e-8)" "unprognostic (2.29e-1)" "unprognostic (2.67e-1)" "unprognostic (4.24e-2)" "unprognostic (2.67e-3)" 25.2 3.5 44.0 10.7 92.5 16.3 23.4 47.2 74.1 33.9 53.0 39.0 13.0 67.5 5.0 45.8 38.1 22.6 17.2 44.5 46.7 36.0 36.3 14.3 5.6 65.8 66.3 33.8 33.0 17.0 6.8 29.3 60.9 24.2 15.5 2.9 29.2 37.5 9.7 44.9 13.2 26.4 37.9 26.6 22.3 5.7 74.1 4.6 23.7 7.4 4.9 32.2 39.1 179.2 78.4 36.5 29.8 45.3 3.1 0.0 49.0 8.7 10.4 13.8 11.0 38.9 34.3 0.0 15.3 8.6 4.8 74.6 20.3 69.7 4.7 0.2 16.7 35.1 48.3 9.2 4.0 1.3 16.1 3.9 39.6 2.9 24.4 22.9 9.1 0.3 0.0 0.4 4.6 37.5 0.1 32.0 10.0 21.2 37.0 0.4 14.7 5.5 37.0 58.0 9.9 18.0 17.7 26.7 25.1 27.5 29.0 8.0 16.6 6.0 59.8 0.3 12.3 0.1 0.2 0.1 0.6 3.7 10.7 9.0 3.0 18.2 16.2 1.5 11.1 0.0 5.0 7.3 1.0 0.0 0.5 3.6 24.0 9.4 1.0 0.0 1.7 5.3 44.0 92.5 47.2 74.1 44.5 46.7 65.8 66.3 60.9 37.9 74.1 179.2 3.1 3.2 6.2 15.0 0.7 19.4 19.4 15.1 21.6 5.5 16.0 9.8 7.8 12.8 6.0 47.8 0.0 7.9 14.5 24.7 11.7 26.7 0.9 18.6 18.5 4.0 34.7 0.4 1.0 20.6 9.5 7.4 14.3 23.6 1.3 1.9 3.6 10.1 5.5 0.0 3.2 26.9 18.3 6.5 8.0 1.5 7.5 2.7 5.4 6.5 4.6 9.1 45.3 10.6 90.9 35.3 16.7 25.6 2.8 16.1 2.3 9.5 4.0 0.8 26.3 5.1 25.3 0.2 1.6 25.6 21.5 2.6 9.0 10.5 13.2 32.2 PLEKHG6 "FLJ10665, MYOGEF" ENSG00000008323 "Pleckstrin homology and RhoGEF domain containing G6" Q3KR16 12 6310436-6328506 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.9;intestine: 43.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 117.9;Extravillous trophoblasts: 56.2;Paneth cells: 67.5;Proximal enterocytes: 62.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 153.2;CACO-2: 50.1;CAPAN-2: 27.3;OE19: 48.0;RT4: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041459, HPA058230" Uncertain Supported "Cell Junctions,Centrosome" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Centrosome "HPA041459: AB_10794518, HPA058230: AB_2683645" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" "unprognostic (1.44e-1)" "unprognostic (8.03e-3)" "unprognostic (5.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.20e-2)" "unprognostic (1.22e-1)" "unprognostic (3.13e-1)" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (6.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (4.18e-2)" "unprognostic (5.73e-2)" 15.1 0.3 1.3 4.3 1.2 2.7 12.8 1.5 2.0 7.5 2.1 31.0 36.5 0.5 0.5 33.9 1.0 5.0 0.3 1.0 0.9 2.7 4.5 1.3 0.6 1.4 1.4 0.2 5.6 7.9 5.2 8.5 1.0 3.0 17.9 0.2 13.3 1.3 0.4 12.1 43.4 1.1 0.7 0.5 11.0 0.8 1.3 0.7 3.9 0.2 2.5 15.7 15.0 1.5 0.7 6.0 0.8 0.1 2.9 0.2 153.2 0.3 0.0 0.4 0.3 50.1 27.3 0.3 0.4 0.0 0.2 13.0 0.0 0.4 0.2 0.1 0.1 0.2 1.5 10.2 0.5 0.5 0.4 0.0 0.7 0.2 0.0 0.5 0.1 0.2 0.4 0.3 0.0 7.9 0.0 0.7 12.7 48.0 1.0 0.2 0.2 0.3 0.1 53.2 0.3 0.2 1.2 23.1 0.3 10.9 7.5 0.0 1.2 0.2 0.5 0.6 0.2 0.0 0.1 0.1 0.8 0.7 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 1.3 1.2 1.5 2.0 1.0 0.9 1.4 1.4 1.0 0.7 1.3 1.5 0.6 0.0 0.0 0.0 0.2 5.0 7.0 2.8 20.5 0.0 4.6 2.9 0.4 8.6 2.5 1.8 0.0 17.6 0.4 117.9 0.0 12.1 1.4 2.9 1.1 0.8 8.4 0.0 0.2 1.8 56.2 1.5 16.3 4.2 0.0 0.5 0.4 2.3 2.7 0.0 0.2 19.3 0.0 0.0 0.7 2.0 2.5 0.3 0.0 0.0 0.2 0.8 2.1 0.0 0.1 2.2 67.5 0.7 0.2 8.4 62.6 0.8 3.0 0.1 0.0 4.7 3.1 0.2 0.5 14.2 7.0 23.9 0.3 0.0 27.9 21.6 PLEKHJ1 FLJ10297 ENSG00000104886 "Pleckstrin homology domain containing J1" Q9NW61 19 2230084-2237704 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.3;Proximal enterocytes: 372.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048989 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA048989: AB_2680590" "unprognostic (5.11e-1)" "unprognostic (4.84e-3)" "unprognostic (2.33e-1)" "unprognostic (9.82e-2)" "unprognostic (1.38e-1)" "unprognostic (7.83e-2)" "unprognostic (2.03e-3)" "unprognostic (2.89e-3)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (9.03e-3)" "unprognostic (3.49e-2)" "prognostic favorable (1.10e-5)" "prognostic favorable (6.99e-4)" "unprognostic (5.67e-2)" "unprognostic (1.15e-1)" "unprognostic (6.26e-3)" 43.4 64.1 41.8 26.4 39.0 38.3 40.5 40.4 51.3 38.8 40.6 109.2 105.2 33.6 18.0 61.3 30.0 19.5 77.6 40.2 39.8 101.1 78.7 42.0 39.3 41.6 41.7 44.1 94.1 14.7 36.4 19.7 43.6 43.4 34.0 4.7 52.2 14.3 88.9 51.7 101.5 12.2 40.2 61.4 99.7 68.0 45.3 27.8 69.2 33.2 24.0 40.8 39.7 38.8 93.9 38.2 68.2 83.0 21.8 28.3 40.3 51.6 24.1 54.1 48.9 98.1 43.1 88.4 42.1 35.6 34.7 71.6 65.4 34.0 16.1 90.8 83.7 46.3 44.5 129.0 34.7 98.6 68.9 41.6 34.2 25.8 23.1 21.5 34.9 75.4 99.5 101.0 39.8 61.3 97.0 88.0 122.6 55.6 52.1 114.7 47.5 108.8 55.7 92.0 170.2 94.1 32.6 58.7 104.5 27.3 78.6 98.2 36.6 23.0 68.7 69.7 56.7 147.3 97.2 101.3 67.4 94.8 30.1 88.2 76.4 129.6 86.9 98.2 77.1 118.8 85.9 91.8 80.8 143.2 69.0 67.2 66.1 53.8 108.3 159.0 112.6 97.2 41.8 39.0 40.4 51.3 40.2 39.8 41.6 41.7 43.6 40.2 45.3 38.8 25.9 38.5 21.1 9.8 67.0 34.8 54.6 61.5 20.5 22.0 60.0 68.1 40.0 87.2 37.8 46.0 16.7 89.8 65.8 356.3 164.4 121.1 68.5 33.2 33.4 26.7 54.0 39.8 12.1 179.5 99.3 46.0 121.8 35.2 18.4 117.1 25.7 49.2 95.4 25.2 11.7 228.5 95.6 43.9 33.3 115.6 47.2 48.1 30.2 9.4 74.7 31.9 65.9 12.1 7.6 146.6 233.3 35.3 49.0 82.2 372.5 148.4 29.1 22.7 32.9 18.9 47.5 93.7 100.7 47.2 42.6 47.7 52.6 81.4 254.1 58.4 PLGRKT "AD025, C9orf46, FLJ14688, MDS030, Plg-RKT" ENSG00000107020 "Plasminogen receptor with a C-terminal lysine" Q9HBL7 9 5357971-5437925 "Predicted intracellular proteins" "Chemotaxis, Inflammatory response, Plasminogen activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 191.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 244.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 247.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008214, HPA011144" Supported Uncertain Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA008214: AB_1078363, HPA011144: AB_1078364" "prognostic favorable (5.56e-4)" "unprognostic (5.31e-2)" "unprognostic (2.96e-2)" "unprognostic (9.67e-2)" "unprognostic (1.05e-1)" "unprognostic (2.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.45e-3)" "unprognostic (2.19e-2)" "unprognostic (1.84e-1)" "prognostic favorable (5.09e-5)" "unprognostic (1.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" 18.9 17.9 9.6 20.2 10.5 13.6 25.4 10.3 13.8 18.1 15.3 41.2 44.1 12.3 27.7 20.3 19.8 15.6 33.6 9.5 10.1 33.4 21.6 14.6 23.9 10.3 9.8 10.0 12.5 19.9 10.4 15.0 10.7 17.4 46.8 15.8 16.7 13.5 58.6 16.4 36.3 17.3 10.6 14.5 20.0 4.8 9.8 35.3 24.8 37.1 22.7 17.6 12.8 11.1 54.8 15.4 31.8 23.0 20.0 27.7 0.1 26.2 29.0 22.1 25.5 0.2 24.2 12.4 13.7 19.8 32.7 12.6 21.9 72.0 46.1 247.5 14.0 97.6 12.5 17.4 43.3 29.8 22.4 30.6 25.8 20.6 42.0 18.9 32.2 41.0 5.5 86.2 54.3 12.0 32.1 33.6 20.6 44.5 8.9 20.1 15.6 39.6 50.6 11.4 25.1 32.7 26.0 40.6 50.6 22.5 32.8 41.4 23.1 28.0 34.8 24.7 51.7 16.4 25.3 25.6 48.6 18.6 16.1 244.3 18.8 38.3 43.0 25.5 54.0 48.9 53.7 56.7 27.6 42.9 51.1 51.2 22.8 52.7 17.9 44.3 74.9 44.0 9.6 10.5 10.3 13.8 9.5 10.1 10.3 9.8 10.7 10.6 9.8 11.1 27.8 12.8 25.5 25.5 22.0 26.4 23.4 144.2 27.3 11.8 56.9 58.7 58.7 22.8 49.7 22.0 0.0 88.6 23.1 139.2 109.5 82.5 0.8 39.6 28.1 21.2 26.5 25.2 18.8 51.1 108.7 25.3 20.9 22.0 90.7 14.6 15.0 27.5 82.8 10.1 26.7 124.2 83.4 21.7 35.6 1.9 16.4 33.0 33.8 21.5 84.3 24.4 24.7 20.1 40.5 82.7 157.2 19.9 23.0 27.3 191.3 76.8 52.6 15.1 0.0 26.0 33.2 21.2 13.7 41.1 30.3 65.8 33.0 23.1 106.1 24.0 PLIN3 "M6PRBP1, PP17, TIP47" ENSG00000105355 "Perilipin 3" O60664 19 4838341-4867694 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 268.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006427, HPA066538" Uncertain Supported "Lipid droplets" NA Yes 11000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" "HPA006427: AB_1079289, HPA066538: AB_2685687" "unprognostic (1.18e-1)" "unprognostic (4.86e-2)" "unprognostic (1.55e-2)" "prognostic favorable (2.62e-4)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.27e-5)" "prognostic unfavorable (7.67e-6)" "unprognostic (2.27e-1)" "unprognostic (1.28e-1)" "unprognostic (4.34e-2)" "unprognostic (8.24e-2)" "prognostic unfavorable (9.15e-7)" "unprognostic (2.62e-1)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (2.39e-2)" 30.8 69.9 23.3 41.4 39.6 70.8 29.5 44.2 27.5 50.4 25.9 37.6 70.8 22.6 14.4 124.7 22.9 34.5 25.3 22.1 28.6 38.0 26.5 25.7 29.1 51.1 36.1 40.0 20.3 9.8 9.3 33.3 48.9 28.0 20.9 1.7 45.9 21.0 112.0 87.5 73.9 23.9 36.2 32.3 28.5 34.3 39.1 28.0 24.8 36.4 33.0 37.5 55.4 66.0 138.2 79.1 53.6 50.5 59.8 189.8 24.1 196.8 178.9 152.0 142.9 52.6 124.9 72.5 43.3 242.2 82.1 61.3 25.1 108.2 88.2 82.7 35.4 79.1 43.0 97.8 41.4 56.7 112.9 147.1 46.2 107.4 23.6 90.5 81.2 23.5 122.4 31.3 192.1 57.1 78.3 72.9 42.5 63.3 127.7 136.2 74.9 40.2 133.8 31.7 2.3 26.3 62.5 55.5 49.5 43.2 70.4 125.9 125.1 83.3 80.5 333.8 102.9 44.1 58.9 50.8 250.7 79.6 97.3 128.3 141.7 64.8 13.8 100.4 14.6 46.3 24.7 15.9 109.1 36.3 19.4 12.4 173.9 39.5 76.7 82.8 34.1 86.4 23.3 39.6 44.2 27.5 22.1 28.6 51.1 36.1 48.9 36.2 39.1 66.0 19.2 19.2 25.6 5.5 28.5 142.2 62.9 58.8 90.0 0.4 108.0 43.1 2.3 14.3 51.3 11.0 2.1 152.2 34.4 169.7 37.2 114.7 9.7 65.2 50.9 27.7 40.7 18.5 0.8 86.8 77.3 62.9 33.1 78.4 55.8 112.9 26.0 18.2 101.2 0.0 1.1 67.0 28.5 57.8 103.4 14.0 35.8 74.7 55.2 2.8 62.3 23.9 15.5 5.0 17.1 243.4 223.0 53.0 37.1 39.3 268.8 38.8 65.2 0.7 52.6 37.8 66.2 75.1 14.6 109.0 229.3 194.8 20.3 193.4 54.8 69.2 PLS1 "I-plastin, Plastin-1" ENSG00000120756 "Plastin 1" Q14651 3 142596393-142713664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 315.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 471.4;Intestinal goblet cells: 147.9;Paneth cells: 200.5;Proximal enterocytes: 335.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 36.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.6;NK-cells: 3.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "A-431: 90.0;BEWO: 112.3;OE19: 166.4;RPTEC TERT1: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055744, HPA061936" Enhanced NA NA 56000000 "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055744: AB_2682903, HPA061936: " "unprognostic (1.29e-1)" "unprognostic (2.61e-1)" "unprognostic (3.15e-3)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.33e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (4.84e-4)" "unprognostic (3.14e-2)" "prognostic favorable (8.76e-6)" "unprognostic (1.99e-2)" "unprognostic (8.64e-2)" "unprognostic (7.22e-2)" "unprognostic (3.82e-2)" 1.6 3.9 0.8 18.8 1.3 7.4 5.7 2.7 2.2 10.1 11.7 144.2 191.6 3.3 3.1 9.6 7.7 27.7 1.2 1.1 1.4 26.7 27.5 14.8 1.7 3.3 0.3 0.9 12.2 15.7 6.2 1.5 3.2 3.1 139.1 24.9 9.1 1.9 0.9 3.6 315.6 4.3 0.3 0.9 45.8 7.5 0.4 5.9 7.7 0.9 2.9 19.6 3.7 1.4 90.0 69.2 4.8 10.4 0.7 0.0 112.3 1.7 2.3 9.4 20.1 31.7 68.8 15.2 35.8 0.1 31.9 18.9 18.8 28.7 20.0 5.5 27.0 27.2 10.2 11.4 0.9 13.0 1.7 0.1 4.7 17.8 11.4 14.8 4.5 16.4 11.8 1.7 1.1 21.0 21.4 7.0 18.9 166.4 25.9 8.7 20.3 12.7 143.6 81.7 24.1 9.7 10.0 7.0 7.8 13.3 55.6 2.2 1.2 1.1 11.3 3.5 21.3 12.7 12.6 18.1 3.2 12.8 3.5 1.9 0.2 2.6 1.5 0.2 2.0 0.3 1.8 2.0 0.4 0.3 2.2 2.6 1.8 3.2 0.2 0.5 1.3 1.0 0.8 1.3 2.7 2.2 1.1 1.4 3.3 0.3 3.2 0.3 0.4 1.4 0.6 54.5 38.0 1.3 1.6 2.9 4.1 23.2 2.8 3.4 9.7 4.2 3.1 54.3 46.8 44.1 16.7 5.8 0.7 471.4 21.5 21.8 64.3 22.2 1.8 0.7 53.9 5.9 18.7 34.0 1.9 1.1 50.0 26.8 8.9 32.3 1.1 31.5 0.6 5.0 25.2 147.9 24.4 1.6 1.0 20.5 1.2 1.4 1.8 5.6 0.8 2.8 0.0 4.0 3.1 70.2 200.5 0.0 2.8 6.8 335.1 40.6 42.2 13.4 0.0 1.2 1.9 4.6 4.1 7.6 3.3 1.4 1.8 1.3 85.2 20.7 PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818914-825573 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 508.1;breast: 361.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "HPA055173: AB_2682725, HPA062602: AB_2684804, HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" 508.1 75.3 11.9 9.2 14.0 43.1 361.4 13.6 18.8 42.2 13.4 58.1 19.3 49.2 2.8 39.9 50.8 9.5 171.3 11.9 14.0 61.9 58.4 57.3 8.1 17.5 11.8 50.5 75.4 9.6 46.3 8.4 16.8 46.6 4.8 1.3 81.1 16.7 194.6 71.8 74.7 6.4 12.6 51.2 71.3 32.1 12.8 10.9 55.3 64.3 4.1 64.8 44.5 15.3 33.9 26.0 5.3 14.0 194.4 17.2 34.1 35.3 28.1 21.6 19.1 22.3 33.3 19.9 20.4 26.7 13.6 30.0 8.1 14.6 6.6 25.9 71.5 27.6 11.2 36.3 63.3 19.2 33.4 33.9 18.7 14.5 16.7 22.3 17.7 14.5 23.8 19.9 19.5 20.0 25.8 42.3 15.2 34.3 55.1 24.6 11.5 45.7 21.4 7.7 19.6 26.0 65.3 55.0 21.9 3.4 23.7 22.0 32.5 19.3 15.0 12.7 16.3 75.2 49.8 16.7 48.4 27.0 13.8 11.5 9.5 22.1 3.7 6.1 3.6 4.7 4.8 5.4 6.1 4.1 5.4 4.4 8.2 4.0 7.1 7.0 4.2 4.7 11.9 14.0 13.6 18.8 11.9 14.0 17.5 11.8 16.8 12.6 12.8 15.3 78.1 6.4 11.8 12.7 63.5 44.2 69.2 34.2 42.1 14.0 79.5 67.1 45.5 61.5 65.2 51.5 8.4 70.2 50.8 151.8 33.2 65.1 22.1 58.0 31.8 51.8 51.5 52.6 8.9 65.3 32.0 37.4 204.4 114.3 11.4 42.2 100.6 50.6 29.2 11.8 7.5 96.1 20.3 27.6 29.0 6.2 48.4 46.6 42.7 16.9 29.6 32.2 21.6 5.5 13.8 142.2 170.7 39.1 92.0 78.5 166.8 45.0 31.3 9.0 65.7 64.4 50.7 33.5 23.9 53.7 41.2 169.4 53.3 182.2 43.6 195.5 POF1B "FLJ22792, POF" ENSG00000124429 "POF1B actin binding protein" Q8WVV4 X 85277396-85379717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.2;skin 1: 123.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 129.8;Gastric mucus-secreting cells: 48.9;Intestinal goblet cells: 61.1;Paneth cells: 62.5;Proximal enterocytes: 73.6;Squamous epithelial cells: 39.2;Undifferentiated cells: 51.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 44.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory B-cell: 2.9;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Group enriched" "Detected in some" 5 "OE19: 179.0;RT4: 78.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002033, HPA050027" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 200000 "Cluster 19: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA002033: AB_1079650, HPA050027: " "unprognostic (2.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.54e-3)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.97e-1)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (1.86e-1)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (1.17e-2)" "unprognostic (2.50e-1)" "unprognostic (4.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.81e-1)" "unprognostic (5.57e-4)" "unprognostic (1.01e-2)" 0.7 0.3 0.1 6.1 0.1 0.2 11.0 0.8 0.3 6.4 0.0 54.2 34.4 0.2 0.5 33.1 6.2 9.0 10.6 0.1 0.0 1.4 0.4 1.8 0.5 0.0 0.0 0.1 6.9 0.0 0.3 1.0 0.0 2.9 50.9 0.4 8.5 1.3 0.8 123.9 43.4 2.0 0.0 3.5 23.7 0.2 0.0 0.5 0.5 0.0 12.0 14.3 14.7 0.0 3.7 22.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.5 23.9 12.0 3.3 0.0 0.1 23.7 5.1 0.4 0.0 2.4 0.1 4.4 0.1 0.1 0.0 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.3 0.7 3.9 0.0 9.6 0.1 0.2 0.0 179.0 0.0 0.2 1.0 0.1 0.0 78.2 0.1 0.1 0.0 6.0 0.0 1.8 2.4 1.0 0.2 0.1 0.1 0.2 0.3 2.0 4.8 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.7 1.2 9.1 4.9 7.9 12.0 0.0 2.5 0.8 24.2 8.6 10.2 5.5 0.0 3.2 0.0 129.8 0.0 13.8 0.0 0.3 0.0 1.7 22.8 0.0 0.4 15.6 0.6 3.4 48.9 0.2 0.0 0.0 0.4 0.2 0.3 0.0 0.4 61.1 6.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.4 24.8 62.5 0.0 0.2 3.9 73.6 0.1 9.5 0.0 0.0 0.1 0.9 0.0 0.1 39.2 28.6 5.3 0.3 0.0 51.1 17.1 POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207880-32238658 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 20.9" "Lineage enriched" "Detected in all" 5 "monocytes: 20.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" NA NA 60000 "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "HPA054519: AB_2682515, HPA059935: AB_2684171" "unprognostic (6.61e-2)" "unprognostic (4.10e-3)" "unprognostic (8.83e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (1.62e-1)" "unprognostic (4.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (5.86e-3)" 17.6 10.8 7.9 11.7 8.4 10.5 16.5 7.2 7.7 15.2 9.1 20.0 20.4 14.9 14.4 12.4 20.4 11.4 17.5 7.7 7.3 16.1 30.9 12.2 9.1 9.3 8.3 20.0 13.8 23.8 9.1 16.4 8.0 14.5 19.1 5.9 13.0 18.1 12.8 13.7 24.0 18.1 8.0 9.4 11.1 9.5 8.1 10.5 18.9 14.0 10.0 14.0 10.9 8.2 47.1 37.2 31.5 34.7 52.9 51.4 58.8 47.8 56.2 78.8 51.3 111.9 62.1 31.7 69.8 53.5 87.2 51.2 30.5 59.0 68.0 16.5 19.2 47.1 32.1 51.2 41.2 41.0 28.9 45.4 45.7 59.7 38.8 33.5 44.6 30.0 36.3 17.6 55.6 23.1 28.4 31.4 16.2 45.2 59.4 23.3 83.6 29.5 24.2 30.7 20.6 26.5 109.5 30.0 41.0 24.0 44.7 48.5 38.8 113.4 42.2 71.8 82.4 21.4 29.3 28.7 68.5 139.9 73.0 4.3 5.4 2.6 3.2 15.1 3.6 3.2 2.8 3.0 4.6 2.6 3.6 2.5 1.0 2.0 20.9 3.4 3.3 4.2 7.9 8.4 7.2 7.7 7.7 7.3 9.3 8.3 8.0 8.0 8.1 8.2 7.8 9.6 9.5 11.1 5.2 2.9 4.7 8.6 5.2 3.1 7.2 7.1 13.4 8.6 7.9 7.3 2.1 15.2 5.7 17.5 1.9 10.0 0.9 7.1 10.8 9.3 12.0 9.2 9.0 10.4 28.2 12.0 9.2 13.6 5.1 13.1 13.9 39.8 10.7 8.4 9.0 13.4 2.0 8.1 3.8 1.7 10.5 6.5 5.4 6.5 9.3 5.2 3.1 11.1 9.6 9.6 11.9 14.3 8.2 6.7 31.7 5.3 7.2 4.3 13.1 11.1 9.4 2.9 7.3 9.7 1.7 7.7 5.0 26.0 19.0 4.1 POLD4 "p12, POLDS" ENSG00000175482 "DNA polymerase delta 4, accessory subunit" Q9HCU8 11 67350772-67356972 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 538.2;Paneth cells: 572.5;Proximal enterocytes: 403.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 177.0" "Low region specificity" "Detected in all" HPA078008 Approved "Centriolar satellite" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite" "HPA078008: " "unprognostic (7.55e-3)" "unprognostic (2.71e-1)" "unprognostic (3.93e-2)" "unprognostic (2.75e-1)" "unprognostic (1.19e-2)" "unprognostic (1.03e-1)" "unprognostic (8.25e-2)" "unprognostic (1.43e-2)" "unprognostic (4.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.19e-2)" "unprognostic (2.53e-1)" "unprognostic (2.39e-3)" "unprognostic (1.70e-1)" "unprognostic (4.11e-2)" "unprognostic (1.95e-1)" "unprognostic (9.36e-2)" 80.6 78.1 9.5 60.4 9.8 37.1 66.5 8.3 19.6 60.6 9.7 110.1 86.0 53.1 5.6 118.3 47.3 19.1 98.4 8.9 8.5 106.9 272.0 73.5 83.1 12.0 11.1 48.3 104.8 4.0 39.7 17.2 11.2 87.1 14.7 3.0 72.7 9.5 91.7 56.2 118.8 9.8 8.9 111.5 81.7 27.9 11.4 8.7 49.3 9.3 25.3 82.1 75.4 10.0 48.0 125.5 2.0 13.6 14.4 27.8 7.6 58.3 12.1 8.5 6.0 21.9 147.7 126.4 177.0 16.9 31.1 64.2 0.4 39.5 1.1 53.4 7.2 29.1 29.6 29.2 31.9 10.3 142.1 31.4 19.7 15.4 13.1 42.6 25.4 19.5 27.1 42.2 14.3 79.4 13.2 22.7 10.1 94.7 83.7 21.6 23.4 34.7 19.9 33.1 1.0 13.2 29.7 21.9 95.8 6.9 51.8 37.5 82.5 28.7 20.2 75.2 19.8 52.9 19.1 72.4 95.8 24.3 34.3 129.3 147.8 258.6 63.2 192.4 59.1 333.3 72.5 65.6 143.8 354.7 78.9 71.0 143.4 50.7 376.9 101.1 115.6 128.9 9.5 9.8 8.3 19.6 8.9 8.5 12.0 11.1 11.2 8.9 11.4 10.0 8.0 19.2 44.9 12.4 115.3 43.3 3.1 152.6 47.8 2.6 14.8 8.6 2.3 12.8 86.1 7.3 6.2 8.6 15.5 538.2 15.6 144.7 7.8 4.8 7.8 19.1 83.1 26.1 6.5 188.5 10.5 25.3 180.4 11.9 68.5 5.6 22.1 40.7 31.3 3.3 4.9 226.0 105.8 31.3 92.5 18.7 6.8 66.9 60.5 34.7 114.1 4.2 36.0 5.5 12.6 220.3 572.5 3.8 66.8 4.5 403.3 30.2 18.7 4.2 6.6 5.8 26.8 4.7 3.0 96.4 68.9 12.4 49.4 2.2 130.8 4.5 POLR2H RPB8 ENSG00000163882 "RNA polymerase II, I and III subunit H" P52434 3 184361718-184368596 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037745, HPA055813" Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA037745: AB_10672914, HPA055813: AB_2797254" "unprognostic (3.21e-1)" "unprognostic (4.96e-3)" "unprognostic (3.61e-3)" "unprognostic (7.15e-2)" "unprognostic (1.17e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (8.82e-3)" "unprognostic (2.84e-1)" "unprognostic (4.02e-3)" "unprognostic (4.24e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.34e-1)" "unprognostic (4.01e-1)" "unprognostic (1.71e-1)" "unprognostic (2.93e-3)" 41.6 60.6 50.4 32.5 51.0 31.1 42.2 53.5 60.1 48.8 51.8 54.4 57.6 36.3 39.7 52.1 39.8 30.0 34.8 50.7 49.9 77.5 63.8 37.6 41.1 50.8 50.6 40.2 52.1 35.5 32.9 34.9 50.9 42.9 57.8 14.6 44.2 26.3 37.3 37.8 55.5 35.0 49.8 41.9 51.2 32.3 51.3 39.8 48.3 30.0 40.8 43.4 41.5 52.9 225.2 77.3 81.7 121.4 89.0 62.8 101.2 82.8 86.3 110.8 141.6 199.6 104.6 126.0 201.7 65.0 168.4 88.8 147.4 148.7 98.1 124.4 194.7 121.4 89.8 126.2 80.1 129.3 67.9 81.6 83.3 72.6 129.8 99.4 116.3 124.6 95.3 81.0 89.0 265.6 128.7 172.3 89.0 279.0 159.3 74.3 74.9 171.2 133.9 100.3 122.8 87.3 69.7 214.0 126.9 78.6 267.9 102.4 61.5 52.5 82.9 70.9 224.3 161.7 181.3 237.3 83.4 136.2 71.5 8.3 17.6 15.9 26.8 30.7 32.9 32.9 31.6 29.1 34.0 33.9 45.8 34.8 1.3 29.8 19.2 34.7 36.7 21.6 50.4 51.0 53.5 60.1 50.7 49.9 50.8 50.6 50.9 49.8 51.3 52.9 45.1 38.5 43.8 23.8 39.4 113.4 74.1 113.7 61.5 22.0 70.1 77.0 17.4 47.1 70.2 44.1 16.7 103.2 45.8 132.8 140.8 73.0 21.0 62.3 62.3 57.9 55.7 53.8 12.9 91.2 146.0 52.8 53.5 83.7 31.1 50.4 43.2 58.5 61.4 25.2 15.8 80.2 93.6 21.4 57.5 14.3 46.0 29.9 51.6 9.4 29.0 26.7 32.0 8.5 11.5 97.6 90.9 27.8 52.1 139.7 94.5 150.5 55.1 24.9 39.5 48.0 69.6 92.9 111.0 66.0 74.2 122.3 38.0 71.6 83.1 92.5 POLR2J "hRPB14, POLR2J1, RPB11, RPB11A, RPB11m" ENSG00000005075 "RNA polymerase II subunit J" P52435 7 102473118-102478907 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA046970 Approved Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA046970: AB_2679882" "unprognostic (1.11e-1)" "unprognostic (1.24e-2)" "unprognostic (1.46e-2)" "unprognostic (1.62e-1)" "unprognostic (1.90e-2)" "unprognostic (4.80e-2)" "unprognostic (6.47e-2)" "unprognostic (4.26e-2)" "unprognostic (3.46e-1)" "unprognostic (1.53e-3)" "unprognostic (4.46e-2)" "unprognostic (7.32e-2)" "unprognostic (7.13e-2)" "unprognostic (2.45e-1)" "unprognostic (4.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" 54.8 87.0 85.3 36.5 87.4 90.0 51.7 88.2 108.0 48.3 83.2 59.1 46.4 48.1 54.7 60.0 46.5 32.7 125.8 85.3 89.6 71.2 99.4 43.3 46.1 89.2 87.2 59.3 58.6 62.9 66.4 32.5 87.4 59.7 33.9 17.8 58.6 38.2 195.7 56.5 51.1 28.3 88.3 59.1 63.6 43.6 90.2 53.2 56.0 127.7 40.1 51.1 48.1 88.4 143.4 143.0 96.2 127.5 89.2 68.5 70.4 77.4 82.3 111.2 94.2 131.1 108.4 65.7 145.9 108.7 160.2 74.8 89.8 95.6 67.8 123.3 160.4 65.9 101.2 129.1 108.9 128.5 94.6 89.6 117.4 100.1 55.8 72.5 100.8 138.3 156.8 190.0 92.5 439.6 212.9 228.5 89.5 141.4 182.2 100.1 94.4 194.0 91.2 93.6 81.4 135.6 93.5 176.1 113.9 97.3 79.1 155.3 82.3 125.0 160.0 198.4 154.5 116.5 183.6 171.0 111.3 157.8 149.1 180.3 116.5 199.5 90.5 122.5 86.2 137.6 96.0 101.0 93.8 122.9 81.4 81.8 174.6 84.7 115.5 127.5 140.8 128.9 85.3 87.4 88.2 108.0 85.3 89.6 89.2 87.2 87.4 88.3 90.2 88.4 87.9 35.3 46.7 17.9 91.1 95.0 113.5 190.7 79.1 37.0 149.6 195.2 193.2 81.5 107.4 125.0 12.5 197.7 93.0 241.7 273.9 139.0 53.1 84.1 64.4 86.8 103.0 128.2 5.6 199.6 195.5 94.4 78.0 73.2 43.7 90.7 86.0 203.5 202.5 35.3 6.2 164.0 146.5 111.0 107.6 43.2 127.1 99.5 142.3 4.7 154.0 171.3 127.7 8.5 10.8 191.8 281.6 110.6 111.4 128.9 236.3 242.0 107.0 46.7 52.6 76.9 113.2 117.1 229.3 114.3 116.1 182.1 91.4 114.5 131.2 153.9 PPARD "FAAR, NR1C2, NUC1, NUCII" ENSG00000112033 "Peroxisome proliferator activated receptor delta" Q03181 6 35342558-35428191 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 67.7;Pancreatic endocrine cells: 102.5;Syncytiotrophoblasts: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017635 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB017635: AB_1128605" "unprognostic (3.70e-2)" "unprognostic (8.75e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (8.68e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (4.59e-3)" "unprognostic (4.34e-1)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.51e-3)" "unprognostic (7.27e-3)" "unprognostic (1.43e-1)" "unprognostic (9.42e-2)" "unprognostic (5.95e-2)" "unprognostic (2.00e-2)" 21.0 20.6 31.9 18.7 30.2 9.1 18.4 27.4 35.3 25.3 22.2 24.2 11.6 19.1 18.4 45.9 19.7 14.9 23.0 35.9 26.5 29.9 31.8 31.5 15.5 31.3 31.5 32.0 12.2 14.2 24.6 28.3 31.2 28.2 12.3 10.9 20.5 17.2 29.4 28.9 27.4 11.3 29.1 30.7 29.8 14.1 36.1 7.6 40.9 13.4 13.8 23.5 33.7 27.8 51.0 8.9 13.7 29.3 20.0 34.9 74.3 40.6 36.1 34.2 28.4 12.0 9.4 8.1 11.6 29.1 19.4 17.8 13.0 39.4 23.8 11.8 11.8 7.7 12.2 17.9 35.0 1.9 8.3 59.7 13.0 50.7 25.9 39.0 16.2 9.9 8.1 8.9 29.1 16.1 5.6 8.2 6.7 19.1 23.9 7.9 23.5 8.2 8.5 44.7 7.7 21.4 16.3 27.9 34.5 9.4 10.4 28.1 35.1 46.3 17.5 28.1 49.1 7.5 11.2 8.7 15.2 16.3 21.2 0.5 1.5 3.3 1.2 1.3 0.9 1.3 1.3 1.2 1.3 1.7 2.2 2.1 2.3 1.0 0.9 0.8 1.4 1.1 31.9 30.2 27.4 35.3 35.9 26.5 31.3 31.5 31.2 29.1 36.1 27.8 14.8 9.6 7.8 11.8 8.8 18.7 19.5 7.5 5.7 7.6 6.6 6.2 11.0 10.0 11.6 1.8 2.1 35.6 3.2 67.7 3.9 30.9 3.0 9.7 8.5 11.9 6.6 1.7 24.4 24.1 32.1 8.0 31.6 18.3 22.9 5.5 6.1 5.6 14.9 5.0 18.7 9.2 10.2 6.6 18.3 3.6 5.9 17.0 12.4 59.0 4.3 8.0 6.2 23.1 42.8 102.5 38.6 8.2 6.1 18.5 22.6 6.3 5.1 7.5 13.1 9.6 10.2 6.2 7.7 7.2 12.8 98.1 7.1 18.8 8.1 51.4 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398181-67421183 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: AB_2679829" "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favorable (1.17e-4)" "unprognostic (7.60e-2)" 70.0 102.4 61.2 102.6 70.8 127.8 63.5 64.0 70.7 62.1 61.2 110.8 95.9 50.5 66.8 184.0 61.1 51.2 122.0 63.5 63.6 121.8 128.2 78.9 147.8 68.3 62.4 33.1 105.1 64.2 59.8 83.5 63.8 81.1 89.6 21.6 100.4 51.0 123.2 105.8 107.1 56.1 63.9 148.7 102.7 34.6 65.8 113.7 88.7 81.3 155.6 74.9 80.6 68.2 283.1 305.6 181.1 270.3 88.4 108.9 185.6 136.1 158.4 267.4 202.3 445.8 328.5 237.2 227.3 208.1 198.4 238.7 213.9 280.2 169.6 256.3 139.9 227.5 129.3 232.7 195.2 295.2 281.1 123.3 181.1 225.7 130.7 125.4 272.2 226.0 217.4 191.1 220.5 619.4 378.2 562.2 303.5 526.7 241.1 262.7 254.0 209.8 262.2 220.7 142.5 236.7 159.2 283.0 439.8 135.3 338.5 201.2 196.4 208.5 208.9 245.3 179.0 190.1 193.2 271.8 244.6 199.9 224.3 921.6 735.9 1234.1 779.2 962.9 604.3 733.4 679.9 792.5 705.3 779.6 412.6 584.2 853.8 688.8 1186.1 500.4 1098.7 2042.5 61.2 70.8 64.0 70.7 63.5 63.6 68.3 62.4 63.8 63.9 65.8 68.2 49.2 76.9 92.2 8.8 165.8 99.9 143.5 305.9 64.3 35.5 81.7 79.1 8.4 102.9 157.8 86.5 10.4 360.4 151.2 377.5 213.2 265.6 2.5 63.1 67.2 101.6 96.9 108.8 8.8 311.1 507.0 68.8 132.0 107.1 109.6 87.1 89.3 113.9 377.1 43.7 7.7 241.3 181.0 219.8 138.5 7.7 49.0 186.5 136.9 9.4 353.0 53.8 408.8 6.0 13.1 318.4 308.4 28.6 206.5 139.0 341.3 297.4 70.5 30.5 98.6 67.1 100.7 13.6 94.6 142.0 121.6 427.3 176.3 100.1 231.7 205.4 PPP1R14D "CPI17-like, FLJ20251, GBPI-1, MGC119014, MGC119016" ENSG00000166143 "Protein phosphatase 1 regulatory inhibitor subunit 14D" Q9NXH3 15 40815451-40828709 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 111.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 334.5;Paneth cells: 338.1;Proximal enterocytes: 412.4;Undifferentiated cells: 108.9" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.6;RPMI-8226: 3.1;RT4: 1.9;SK-BR-3: 1.2;T-47d: 1.1;U-266/84: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA041846 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041846: AB_10794307" "unprognostic (1.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (5.91e-3)" "unprognostic (1.17e-2)" "unprognostic (4.68e-2)" "unprognostic (1.89e-1)" "unprognostic (7.74e-2)" "unprognostic (2.86e-1)" "unprognostic (5.26e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.55e-1)" "unprognostic (1.43e-2)" "unprognostic (3.74e-3)" "unprognostic (3.11e-2)" 0.1 0.0 0.1 9.6 0.1 0.0 0.5 0.5 0.1 0.3 0.1 107.1 111.1 0.2 1.9 0.2 0.3 15.6 0.1 0.1 0.0 3.8 0.1 0.2 0.2 0.1 0.2 0.0 0.3 0.4 0.1 0.1 0.1 0.7 92.5 0.2 0.7 0.4 0.0 1.0 82.3 3.6 0.1 0.0 1.7 0.2 0.1 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.9 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 1.0 0.0 0.0 0.0 3.1 0.0 1.9 0.4 0.3 0.0 1.2 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.3 0.0 0.0 0.5 0.9 0.0 5.7 0.3 1.8 0.0 0.4 0.1 334.5 0.0 1.3 0.0 0.1 0.0 0.0 61.3 0.0 0.1 5.3 0.0 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.1 0.0 0.2 58.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 338.1 0.0 0.0 0.1 412.4 52.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.4 0.9 0.0 108.9 0.2 PPP1R1B "DARPP-32, FLJ20940" ENSG00000131771 "Protein phosphatase 1 regulatory inhibitor subunit 1B" Q9UD71 17 39626740-39636626 "Metabolic proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 711.8;choroid plexus: 506.6;intestine: 211.4;salivary gland: 366.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 144.6;Distal tubular cells: 121.3;Intestinal goblet cells: 305.7;Melanocytes: 135.2;Paneth cells: 132.3;Undifferentiated cells: 423.7;Urothelial cells: 171.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 94.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 1.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.0" "Cell line enhanced" "Detected in some" "ASC diff: 7.6;CAPAN-2: 12.6;HSkMC: 31.7;OE19: 15.6;SCLC-21H: 27.4" "Region enriched" "Detected in all" 8 "basal ganglia: 1243.8" "Region enriched" "Detected in all" 26 "basal ganglia: 1534.8" "CAB004026, HPA048630, HPA061142" Approved Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB004026: AB_2169007, HPA048630: AB_2680468, HPA061142: AB_2684438" "unprognostic (2.71e-1)" "unprognostic (4.09e-2)" "unprognostic (6.91e-3)" "unprognostic (2.42e-1)" "unprognostic (3.01e-1)" "unprognostic (7.69e-2)" "unprognostic (6.00e-3)" "unprognostic (2.76e-2)" "unprognostic (1.75e-2)" "unprognostic (6.13e-2)" "unprognostic (6.07e-2)" "unprognostic (2.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.52e-3)" "unprognostic (1.55e-1)" 93.8 30.2 280.9 19.8 711.8 0.4 74.0 262.7 312.7 20.0 506.6 211.4 83.4 4.4 5.5 4.8 28.4 2.0 3.5 251.7 244.0 29.1 0.5 15.3 0.1 319.6 275.5 11.3 75.7 0.5 15.0 0.0 232.4 62.7 203.4 6.2 366.9 89.7 0.9 56.3 68.7 10.8 243.3 0.1 39.9 15.8 317.9 0.2 0.6 0.0 0.3 18.9 11.4 249.6 0.0 0.0 0.0 0.0 7.6 4.4 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.9 15.6 0.9 0.0 0.0 0.6 0.0 0.0 27.4 0.6 0.0 1.5 0.0 2.4 0.6 1.1 0.0 0.0 1.8 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 280.9 711.8 262.7 312.7 251.7 244.0 319.6 275.5 232.4 243.3 317.9 249.6 1.0 0.0 34.7 33.3 1.3 1.3 117.1 0.4 0.6 0.6 93.5 84.3 1.1 0.0 0.2 1.8 0.0 0.0 2.4 144.6 121.3 28.7 0.8 46.6 0.9 1.6 96.7 0.0 5.3 3.3 0.0 2.8 13.3 3.2 4.5 0.0 4.2 0.0 0.2 0.0 1.6 305.7 2.0 0.0 0.8 3.2 34.5 1.2 135.2 0.0 0.0 29.8 0.0 1.0 0.5 0.8 132.3 5.7 0.0 84.3 40.4 0.7 0.1 1.3 0.0 1.2 1.7 0.9 3.7 1.2 0.4 0.0 1.9 0.0 423.7 171.5 PPP2CB PP2Abeta ENSG00000104695 "Protein phosphatase 2 catalytic subunit beta" P62714 8 30774457-30814314 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Peritubular cells: 264.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018600, HPA043236" Approved Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB018600: AB_675841, HPA043236: AB_2678379" "unprognostic (9.77e-2)" "unprognostic (1.30e-1)" "unprognostic (2.51e-2)" "unprognostic (3.82e-1)" "unprognostic (6.70e-2)" "unprognostic (7.79e-2)" "unprognostic (1.13e-2)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-2)" "prognostic favorable (5.82e-7)" "unprognostic (9.24e-2)" "unprognostic (2.04e-1)" "unprognostic (1.39e-1)" "unprognostic (2.65e-3)" 89.9 66.6 190.2 42.2 196.1 10.5 68.4 189.1 220.1 84.0 147.9 79.3 72.9 112.1 117.1 95.1 87.8 74.2 94.7 191.6 190.7 131.9 118.6 90.6 32.5 199.7 184.1 147.4 75.7 93.3 52.5 91.0 190.4 74.9 76.2 77.9 68.6 87.1 105.7 63.7 87.0 122.3 195.1 52.9 71.2 64.7 204.4 41.4 126.7 122.7 47.4 76.8 70.0 200.1 96.5 82.7 136.4 54.4 134.6 120.0 78.0 124.0 114.0 123.1 129.5 86.6 68.3 45.6 118.7 165.4 117.9 56.5 84.4 142.1 167.3 28.5 44.2 61.8 52.7 86.9 157.3 28.1 34.2 108.6 157.4 105.2 115.9 124.2 152.5 73.6 97.7 47.6 212.4 48.4 77.1 34.9 102.6 139.3 47.0 53.9 55.7 34.5 168.5 73.6 134.3 55.0 57.8 61.1 127.0 150.5 34.1 47.8 164.0 109.1 81.7 36.1 105.5 24.0 33.6 53.7 93.4 26.0 141.4 3.4 2.5 1.7 1.8 3.1 2.3 2.9 1.7 1.9 1.7 1.1 1.7 2.1 2.3 3.8 1.5 3.8 1.3 0.8 190.2 196.1 189.1 220.1 191.6 190.7 199.7 184.1 190.4 195.1 204.4 200.1 81.0 70.5 60.7 68.6 13.0 104.1 115.9 44.4 44.9 36.6 64.9 51.8 80.2 45.8 54.3 86.5 31.3 41.1 23.6 186.1 46.9 40.6 21.8 98.5 109.8 60.9 32.3 16.6 41.0 48.9 52.8 79.0 34.7 89.2 17.7 95.4 87.8 95.5 58.4 47.1 59.1 65.3 28.5 55.4 60.4 20.3 73.3 36.0 40.9 52.5 27.4 127.2 17.5 37.7 60.4 81.1 78.9 264.0 15.8 125.4 115.6 95.9 68.2 26.5 46.0 93.1 73.0 37.2 40.4 50.3 95.6 70.6 17.4 75.3 41.2 149.9 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085376 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: AB_2678695" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 44.3 57.9 34.8 43.2 34.7 63.2 42.5 35.9 38.7 42.8 41.0 49.8 47.0 39.6 47.1 88.3 35.9 32.5 45.6 34.0 35.7 49.9 83.2 46.2 58.6 35.5 34.9 29.4 41.0 46.4 33.5 49.6 35.3 37.8 35.2 18.1 44.0 28.5 60.8 60.8 49.0 32.8 35.6 62.5 49.2 65.4 38.4 61.2 35.4 30.2 63.7 56.3 48.9 36.4 132.7 145.9 95.5 134.0 88.4 73.8 148.5 115.8 127.7 148.7 163.8 129.5 167.9 102.7 145.2 137.0 95.5 105.9 119.3 143.2 87.0 130.1 213.0 70.5 86.0 290.4 133.5 100.1 126.8 107.9 124.7 135.9 85.5 88.4 174.9 130.5 139.6 91.0 115.1 382.2 174.4 180.7 182.2 104.7 77.1 190.9 99.4 180.4 142.5 134.5 91.9 136.8 57.1 169.1 101.8 79.4 156.0 166.0 113.3 86.4 90.4 70.6 90.8 155.4 183.8 122.4 123.1 126.9 107.0 100.6 103.5 236.1 66.5 113.2 47.7 68.5 69.6 74.2 115.8 88.3 62.0 54.1 215.2 51.7 100.1 90.6 95.1 48.3 34.8 34.7 35.9 38.7 34.0 35.7 35.5 34.9 35.3 35.6 38.4 36.4 87.8 51.3 33.4 10.7 85.8 147.2 121.7 206.9 71.2 23.3 94.2 82.8 11.1 82.9 133.5 77.3 29.2 313.7 106.0 217.0 158.5 226.9 156.9 80.5 55.5 91.7 125.6 89.2 8.0 193.3 335.3 66.7 106.0 85.2 69.2 66.7 74.6 94.2 239.3 35.3 8.6 159.3 193.3 105.4 138.4 143.8 62.7 124.4 80.0 9.4 221.1 61.1 118.4 8.0 12.9 345.5 220.8 52.3 97.6 161.3 191.0 198.6 119.7 29.5 72.3 43.4 85.9 228.5 157.8 113.2 172.5 421.0 93.0 61.7 175.9 227.2 PQBP1 "MRX2, MRX55, MRXS3, MRXS8, RENS1, SHS" ENSG00000102103 "Polyglutamine binding protein 1" O60828 X 48890197-48903143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001880 Supported Enhanced "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA001880: AB_1079671" "unprognostic (7.25e-2)" "prognostic favorable (1.48e-4)" "unprognostic (5.98e-2)" "unprognostic (2.09e-2)" "unprognostic (2.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.78e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-1)" "unprognostic (7.48e-2)" "unprognostic (4.33e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.68e-7)" "unprognostic (2.68e-1)" "unprognostic (2.52e-3)" "unprognostic (3.97e-2)" "unprognostic (5.70e-3)" 38.8 50.6 35.5 25.6 36.9 46.0 39.3 38.1 44.2 47.9 31.1 50.0 39.2 42.5 22.7 48.6 41.0 24.2 43.0 36.7 40.2 41.7 61.0 35.6 31.1 38.8 37.3 58.4 62.8 28.1 50.5 18.2 38.6 42.2 20.4 21.5 43.2 28.3 65.0 52.0 42.2 25.3 38.4 45.2 52.1 13.8 39.0 38.6 38.6 32.3 29.0 39.2 43.2 40.0 100.6 124.3 64.5 63.2 58.2 40.8 48.8 57.3 67.1 116.8 70.7 146.3 45.0 91.8 46.2 40.0 88.1 79.9 110.6 42.6 43.5 80.8 95.2 78.1 94.6 109.5 55.9 95.5 69.8 50.7 81.4 96.8 95.5 46.5 67.0 35.9 75.7 169.0 50.1 167.5 41.5 94.3 60.3 69.3 139.6 66.7 63.0 209.4 75.5 66.2 95.7 49.4 75.3 82.6 66.5 48.0 103.5 68.9 58.6 51.1 92.2 65.6 77.4 99.9 106.5 69.5 29.0 88.0 53.8 41.8 81.9 53.1 56.4 79.1 74.7 83.9 78.2 56.2 96.9 70.4 81.5 74.9 23.4 76.1 73.0 86.9 114.3 84.5 35.5 36.9 38.1 44.2 36.7 40.2 38.8 37.3 38.6 38.4 39.0 40.0 37.0 41.7 65.9 6.2 65.4 111.8 86.1 99.5 85.4 36.7 76.9 97.2 39.0 54.3 68.6 31.3 12.5 58.5 53.4 85.1 49.0 59.9 6.2 37.5 38.6 54.5 70.1 38.7 4.4 95.8 56.1 53.9 39.8 54.3 70.5 36.6 43.5 45.0 70.2 18.5 3.9 68.2 77.3 72.2 113.5 4.9 69.9 56.2 88.9 3.7 96.6 47.4 55.6 3.5 4.8 73.7 123.6 43.6 105.9 54.2 151.1 108.5 51.6 27.7 39.5 64.4 69.8 2.7 17.7 69.5 117.3 54.6 62.9 67.0 67.9 69.3 PRAC1 "C17orf92, PRAC" ENSG00000159182 "PRAC1 small nuclear protein" Q96KF2 17 48721719-48722518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "intestine: 206.4;prostate: 109.0" "Group enriched" "Detected in some" 5 "Distal enterocytes: 326.1;Enteroendocrine cells: 908.1;Intestinal goblet cells: 717.3;Paneth cells: 328.7;Undifferentiated cells: 624.3" "Cancer enriched" "Detected in many" 5 "prostate cancer: 291.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 32 "PC-3: 379.0" HPA047871 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA047871: AB_2680195" "unprognostic (7.59e-2)" "unprognostic (2.43e-2)" "unprognostic (2.04e-1)" 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.2 0.3 4.4 0.1 106.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 109.0 206.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 12.4 12.8 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 379.0 11.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.1 0.4 0.1 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 1.0 0.0 110.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 326.1 0.0 0.0 0.7 0.0 0.0 0.4 908.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 328.7 0.0 0.0 101.9 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.9 0.0 624.3 63.1 PRAC2 "C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253" ENSG00000229637 "PRAC2 small nuclear protein" D3DTV9 17 48723185-48724758 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 9.7;prostate: 13.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.2;Distal enterocytes: 17.5;Early spermatids: 32.9;Enteroendocrine cells: 31.9;Intestinal goblet cells: 15.5;Late spermatids: 60.5;Prostatic glandular cells: 20.2;Undifferentiated cells: 22.7;Urothelial cells: 30.1" "Cancer enriched" "Detected in many" 8 "prostate cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 49.3;REH: 20.0" "Intracellular and membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.26e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-2)" "unprognostic (9.98e-2)" "unprognostic (3.27e-2)" "unprognostic (9.77e-2)" "unprognostic (8.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.3 9.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.4 2.5 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.5 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.2 49.3 20.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.2 0.0 2.8 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 32.9 0.0 0.0 0.1 31.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.3 60.5 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.4 0.0 20.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 22.7 30.1 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477330-173488815 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1315.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 340.7 157.5 169.5 68.3 181.3 100.1 211.2 197.6 210.1 112.3 164.8 189.1 46.4 108.8 206.3 127.9 149.8 71.9 261.8 184.1 196.6 184.4 482.5 116.7 72.2 181.0 198.3 115.5 114.4 217.5 67.4 70.7 187.5 152.1 221.6 53.9 85.6 99.0 563.5 106.6 59.8 160.2 175.8 70.7 135.2 119.1 176.7 70.7 106.0 382.4 79.0 99.5 109.8 185.5 420.3 127.7 204.7 230.9 778.5 372.7 169.5 843.9 284.3 342.7 241.8 243.9 276.4 272.4 256.4 694.2 120.4 239.8 272.0 259.9 279.0 234.0 243.6 179.5 200.0 277.7 425.7 191.3 56.1 301.0 262.6 181.3 256.6 210.8 339.5 106.7 405.4 52.8 392.9 86.3 131.7 249.1 456.2 219.8 760.5 154.5 236.6 277.0 518.1 95.4 94.9 173.4 285.0 334.0 199.2 296.3 283.8 262.9 228.2 132.5 149.9 201.8 229.5 76.4 123.2 220.7 159.4 162.3 124.3 36.2 42.5 24.8 29.8 39.8 32.8 32.6 29.8 38.4 53.5 24.4 39.8 47.9 25.2 25.7 36.5 79.7 36.1 58.1 169.5 181.3 197.6 210.1 184.1 196.6 181.0 198.3 187.5 175.8 176.7 185.5 278.1 176.3 170.8 127.3 127.4 235.4 404.1 382.8 209.5 31.9 186.1 250.7 528.6 301.7 228.6 277.7 29.2 714.3 158.6 1315.9 860.8 178.6 237.5 206.9 226.8 191.8 142.1 449.5 13.8 202.3 939.1 307.0 111.6 200.0 348.6 216.6 214.2 1120.2 345.0 45.4 13.2 257.4 205.4 164.3 161.0 667.5 340.5 227.1 183.2 17.8 212.9 462.5 83.4 12.5 15.4 147.2 663.4 416.8 176.4 427.1 264.4 827.3 209.1 52.0 184.1 185.7 253.8 123.5 76.8 305.9 264.1 963.5 157.7 512.5 303.6 308.9 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 57.0;granulocytes: 52.9;monocytes: 73.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 267.7;THP-1: 194.0" "Group enriched" "Detected in all" 5 "basal ganglia: 121.4;thalamus: 334.6" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 30000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 46.1 59.7 10.4 45.4 11.1 90.3 28.9 4.4 11.7 25.9 7.3 43.5 54.8 9.1 39.1 32.7 42.3 32.8 19.6 12.8 11.0 25.6 8.8 44.3 46.8 9.9 8.5 13.6 33.2 20.7 8.2 20.5 7.5 39.3 41.5 2.2 25.9 31.9 6.8 34.0 55.7 16.2 9.5 54.2 65.1 20.8 9.0 16.3 41.8 9.2 62.1 44.2 23.2 12.3 33.5 14.4 5.2 8.7 35.9 21.6 46.2 20.4 25.7 24.5 23.7 34.4 31.9 86.5 8.3 45.6 42.9 14.5 34.1 49.8 20.6 75.2 23.6 50.1 18.3 32.0 23.6 64.8 103.4 17.1 35.8 25.6 23.2 21.8 22.4 9.3 9.7 11.8 36.1 85.0 7.0 81.0 13.0 51.5 23.0 7.6 13.6 20.6 25.5 72.8 8.3 6.5 15.4 267.7 39.6 24.0 22.6 194.0 31.5 11.7 14.4 15.4 19.2 18.1 33.6 45.9 27.6 116.4 22.6 51.8 73.7 50.1 3.6 71.3 2.2 6.2 2.1 2.5 57.0 8.2 2.2 2.0 52.9 6.9 47.7 16.3 2.6 24.1 10.4 11.1 4.4 11.7 12.8 11.0 9.9 8.5 7.5 9.5 9.0 12.3 4.3 3.2 23.5 2.0 25.7 29.2 26.3 8.0 23.9 0.3 11.8 4.3 6.4 14.3 16.1 14.7 0.0 3.1 24.7 61.8 3.9 8.9 34.5 18.5 4.4 2.7 26.5 5.2 3.4 10.7 16.0 6.7 54.0 17.8 5.7 8.9 3.3 2.3 44.8 1.7 4.2 37.1 4.1 47.4 43.0 75.6 9.0 41.5 10.6 20.6 44.9 2.0 8.2 1.0 0.5 13.2 55.4 6.8 25.8 19.7 64.5 13.1 16.5 0.2 6.6 6.5 12.1 23.1 3.7 23.9 27.8 8.8 10.0 10.4 23.0 34.6 PRMT7 "FLJ10640, KIAA1933" ENSG00000132600 "Protein arginine methyltransferase 7" Q9NVM4 16 68310974-68358584 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044241 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "HPA044241: AB_2678869" "unprognostic (9.33e-2)" "unprognostic (5.33e-2)" "unprognostic (1.52e-1)" "prognostic favorable (2.31e-5)" "unprognostic (2.92e-2)" "unprognostic (1.95e-1)" "unprognostic (4.12e-2)" "unprognostic (1.22e-1)" "unprognostic (3.74e-1)" "unprognostic (1.19e-1)" "unprognostic (4.74e-3)" "unprognostic (3.09e-2)" "unprognostic (7.72e-2)" "unprognostic (1.75e-1)" "unprognostic (9.23e-2)" "unprognostic (3.57e-1)" "unprognostic (1.31e-1)" 9.7 11.9 8.1 6.2 8.3 4.7 10.5 8.4 10.2 9.8 12.0 10.8 3.2 9.4 3.3 7.5 10.7 4.3 13.2 8.3 8.3 8.6 10.2 5.9 9.4 8.9 8.4 12.1 9.7 4.8 11.1 6.3 8.8 10.5 3.0 4.6 10.0 7.0 21.8 9.8 8.8 4.5 8.3 9.7 8.8 9.8 8.4 14.4 8.6 13.5 5.8 9.7 8.3 8.4 18.1 24.7 13.2 36.1 7.1 7.0 50.8 13.8 6.8 19.5 15.6 79.4 16.1 42.4 29.8 14.0 8.4 22.6 20.4 13.8 12.6 12.7 24.5 8.6 30.8 36.8 7.8 24.3 15.8 11.3 4.9 15.2 14.0 9.3 11.8 18.7 28.1 0.8 10.3 28.2 25.8 36.3 25.3 16.5 18.8 43.7 19.3 25.7 10.7 17.7 19.8 13.2 53.5 16.2 15.7 11.9 25.2 22.2 16.0 14.7 12.9 19.9 17.6 9.6 22.5 41.6 17.1 23.4 16.8 12.3 8.2 7.1 17.4 10.6 20.2 10.9 11.6 14.9 11.8 12.8 16.7 15.4 0.8 21.4 9.5 32.9 14.7 14.3 8.1 8.3 8.4 10.2 8.3 8.3 8.9 8.4 8.8 8.3 8.4 8.4 7.1 19.2 10.6 16.6 12.1 6.9 8.9 12.8 9.1 21.2 10.8 8.8 13.3 8.6 10.0 9.2 54.2 25.4 12.6 28.3 5.9 12.3 4.4 12.9 8.7 7.6 13.2 7.8 25.0 16.1 8.4 10.5 23.4 5.9 7.0 24.9 6.8 8.4 12.2 30.3 25.9 32.4 10.2 7.7 20.6 4.3 11.8 6.2 8.8 12.2 9.1 9.7 13.4 18.6 20.4 23.6 29.8 13.2 6.9 6.7 24.7 7.7 14.5 18.2 13.1 9.9 8.6 6.9 19.3 6.1 6.0 11.6 16.5 10.0 24.1 12.7 PRR15 ENSG00000176532 "Proline rich 15" Q8IV56 7 29563835-29567293 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 62.6;intestine: 81.4;stomach 1: 49.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 263.0;Granulosa cells: 194.2;Proximal enterocytes: 122.4;Respiratory ciliated cells: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.7;HaCaT: 45.1;OE19: 97.7;RT4: 34.5;SK-BR-3: 74.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA040996, HPA048121" Enhanced Uncertain "Vesicles,Cell Junctions" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "HPA040996: AB_2677241, HPA048121: AB_2680271" "unprognostic (5.46e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "prognostic favorable (6.37e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (3.69e-3)" "unprognostic (1.25e-1)" "prognostic favorable (1.83e-6)" "unprognostic (1.30e-2)" "unprognostic (5.71e-2)" "unprognostic (2.33e-3)" "unprognostic (1.58e-2)" 6.5 0.7 0.6 4.8 0.4 1.1 9.2 0.1 0.7 62.6 0.0 81.4 72.3 18.1 21.6 1.0 9.0 7.8 1.3 0.4 1.0 16.9 0.3 2.3 0.4 0.6 0.4 5.9 3.0 1.4 3.0 4.8 0.5 2.5 52.6 0.0 7.5 3.1 0.2 0.3 72.4 2.3 0.6 0.2 49.3 0.9 1.3 0.1 1.1 0.0 0.7 16.6 0.5 0.6 16.8 23.3 0.0 0.0 8.7 10.7 29.3 0.7 1.1 0.4 0.2 20.5 38.7 0.0 4.1 5.5 0.6 45.1 4.9 0.0 0.0 0.0 3.3 1.3 4.5 22.7 2.8 0.0 0.1 0.1 7.3 0.0 1.7 0.0 0.1 1.5 0.0 0.0 0.0 3.9 0.6 3.2 3.5 97.7 18.5 0.1 0.0 21.4 26.5 34.5 0.5 0.3 2.3 74.9 0.0 12.8 5.4 0.0 19.9 0.5 0.0 0.1 0.9 1.8 3.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.4 0.1 0.7 0.4 1.0 0.6 0.4 0.5 0.6 1.3 0.6 1.8 0.0 0.5 0.0 0.4 0.1 1.2 11.0 0.0 0.0 10.0 7.1 0.5 12.8 16.4 38.6 0.0 14.2 0.2 263.0 29.4 6.9 0.8 31.3 2.3 1.2 8.4 0.0 0.1 21.8 9.9 1.3 16.8 34.7 0.0 194.2 0.4 0.2 2.7 0.0 0.0 45.3 26.4 0.0 0.3 0.1 1.5 2.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 14.4 58.5 2.2 0.1 3.0 122.4 14.4 63.1 0.0 0.0 0.0 7.8 0.0 0.4 1.2 0.0 6.3 0.6 0.4 56.9 23.3 PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 28.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 47.2;Proximal enterocytes: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.9;OE19: 18.0;RT4: 11.7;SK-BR-3: 13.3;T-47d: 14.4;U-266/84: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA010702: AB_1079693" "unprognostic (2.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (5.60e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "prognostic favorable (3.82e-9)" "unprognostic (4.89e-2)" "unprognostic (1.46e-1)" "unprognostic (6.58e-3)" "unprognostic (3.68e-2)" 1.2 0.4 0.9 1.2 0.9 0.1 7.0 1.3 2.6 4.9 0.6 8.4 12.0 1.5 12.9 13.5 4.9 4.3 1.2 0.9 1.0 11.8 6.4 3.9 0.9 1.2 0.9 0.3 13.1 28.4 15.6 2.1 1.1 6.2 7.7 0.1 11.3 9.0 0.9 12.9 11.0 1.1 0.9 1.0 9.8 0.9 1.1 2.3 13.4 0.1 3.9 6.7 5.5 1.0 11.1 0.4 0.3 0.9 1.3 0.0 4.6 0.2 0.0 0.4 0.4 2.2 14.9 0.7 1.6 0.1 0.3 8.5 0.3 8.5 0.4 1.1 1.2 0.5 0.8 0.7 0.9 0.4 1.1 0.9 7.4 0.3 0.3 0.7 3.4 0.9 0.2 0.8 0.0 2.4 0.2 0.7 0.6 18.0 1.4 0.2 0.3 8.7 6.5 11.7 2.4 0.3 1.3 13.3 0.1 1.0 14.4 0.2 0.6 0.8 0.7 0.4 0.1 5.1 18.7 0.5 0.2 0.3 0.4 0.0 0.2 0.1 0.4 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.2 0.2 0.5 0.0 0.2 1.2 0.2 0.1 0.9 0.9 1.3 2.6 0.9 1.0 1.2 0.9 1.1 0.9 1.1 1.0 6.4 6.4 13.4 0.7 3.4 4.1 11.6 20.2 29.6 2.2 21.5 22.6 0.9 8.6 14.2 12.9 2.1 13.0 4.1 47.2 3.9 31.9 0.7 10.8 4.1 6.4 16.2 1.3 0.5 33.2 6.5 1.6 16.8 16.1 2.5 2.3 1.1 6.8 2.3 5.0 0.4 18.0 8.2 1.9 1.2 0.4 0.3 3.3 1.8 1.9 8.2 0.9 2.1 2.0 0.4 27.4 29.4 0.0 4.4 14.5 46.3 15.5 8.8 4.1 0.0 0.8 3.9 1.9 2.1 23.3 4.7 12.7 4.1 4.6 20.7 14.6 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 268 "pancreas: 31113.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1022.9;Exocrine glandular cells: 2040.4;Pancreatic endocrine cells: 478.8;Paneth cells: 969.9;Proximal enterocytes: 1127.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 158.7" "Lineage enriched" "Detected in many" 104 "granulocytes: 158.7" "Group enriched" "Detected in many" 5 "OE19: 316.6;PC-3: 852.5" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 700000000 "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 3.8 4.6 23.5 7.2 29.3 0.6 1.7 25.8 35.4 30.8 16.9 87.0 92.6 0.4 0.0 116.2 0.3 22.8 6.3 28.2 25.6 3.7 12.4 0.6 0.7 25.0 24.5 12.9 31113.6 0.0 0.7 1.7 25.7 1.1 77.8 0.3 20.9 0.3 0.5 79.7 105.4 3.1 19.4 0.7 22.8 5.1 25.6 0.8 0.4 0.0 15.2 4.2 56.9 24.7 12.0 13.7 0.7 0.0 0.2 5.9 0.1 33.6 7.7 4.1 1.6 34.3 3.0 0.0 0.2 14.9 0.2 15.0 0.0 31.7 10.1 0.4 0.2 0.0 1.1 0.0 2.7 0.0 0.0 0.2 0.0 10.8 110.2 0.3 68.8 0.2 0.0 0.0 0.0 0.2 0.7 0.4 0.2 316.6 852.5 0.0 0.0 0.0 0.0 1.7 0.3 81.2 0.2 0.0 0.0 0.5 0.0 0.0 78.3 0.0 0.0 12.8 0.0 0.0 0.0 0.1 18.1 0.0 0.1 158.7 0.0 0.0 0.2 1.5 1.2 0.0 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.3 23.5 29.3 25.8 35.4 28.2 25.6 25.0 24.5 25.7 19.4 25.6 24.7 0.1 0.0 0.0 0.7 1.9 57.1 0.6 1.3 0.0 0.2 0.1 2.8 1.0 47.1 1.2 1.8 0.0 0.0 0.1 1022.9 3.9 43.2 31.4 0.0 0.0 3.2 192.6 0.0 32.8 2040.4 0.0 0.8 39.3 0.0 8.9 0.0 0.7 4.2 0.0 0.0 4.7 146.4 0.0 0.3 12.1 79.7 1.5 1.2 7.2 3.7 5.7 0.0 0.0 3.5 1.2 478.8 969.9 0.7 0.3 12.1 1127.1 14.7 0.1 0.2 0.0 0.0 1.7 0.5 0.9 1.1 134.1 0.1 2.1 0.0 329.0 56.2 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 259.9;Extravillous trophoblasts: 290.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 314.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" NA NA 160000000 "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favorable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" 91.7 11.9 47.1 14.0 48.4 1.8 57.4 22.3 45.6 36.3 4.7 79.5 70.5 28.0 71.9 101.7 70.5 30.4 7.6 45.3 39.9 27.7 107.2 35.4 4.7 33.1 43.6 22.1 56.8 31.1 23.5 55.7 33.1 67.3 51.4 24.7 101.7 43.1 2.7 107.9 78.5 35.0 30.4 4.0 49.7 9.4 45.6 29.6 23.8 3.4 26.2 40.0 51.2 37.4 165.6 76.5 49.0 58.0 11.2 0.6 274.3 92.1 36.1 73.9 62.6 82.0 214.9 0.4 25.6 40.2 59.2 124.7 57.5 200.7 89.1 2.0 72.1 1.0 48.7 75.3 33.8 1.2 1.3 11.3 113.2 106.4 174.9 92.6 111.5 7.7 25.4 7.1 27.5 94.0 1.2 1.3 75.9 89.8 21.0 57.2 86.9 3.7 28.3 241.5 73.3 28.0 90.8 314.0 11.8 128.8 91.5 17.3 88.2 1.6 116.5 7.5 126.1 3.1 2.7 0.4 7.4 3.9 233.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.1 48.4 22.3 45.6 45.3 39.9 33.1 43.6 33.1 30.4 45.6 37.4 2.3 157.0 101.1 39.2 2.3 62.8 51.3 67.4 52.9 33.5 146.3 102.9 7.6 130.1 74.9 86.5 43.8 64.3 1.4 259.9 0.0 147.4 4.9 80.6 17.2 7.7 100.9 8.0 40.6 120.8 290.1 19.8 93.8 70.6 5.1 72.8 10.4 159.6 14.1 185.1 16.1 171.7 50.8 4.9 5.8 8.5 6.8 3.4 12.4 7.5 2.9 27.2 2.1 16.6 68.1 165.0 124.7 7.2 1.8 68.0 208.1 13.9 128.3 31.0 0.0 15.8 18.5 9.0 37.5 107.5 91.4 66.2 3.9 9.6 142.5 78.7 PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase receptor type H" Q9HD43 19 55181247-55209506 "Enzymes, Metabolic proteins, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 24.2;intestine: 68.6;stomach 1: 23.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 123.6;Gastric mucus-secreting cells: 60.1;Paneth cells: 94.9;Proximal enterocytes: 113.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 11.8;K-562: 15.0;OE19: 30.9;SK-MEL-30: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042300 Approved Mitochondria NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA042300: AB_10796900" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" 1.3 16.9 1.7 3.6 4.4 0.0 0.6 5.2 3.0 0.8 0.9 27.9 67.7 0.7 0.1 0.3 0.5 24.2 1.1 1.7 3.4 0.2 13.3 0.1 0.1 7.1 4.9 0.3 4.6 0.1 5.1 0.1 5.7 0.2 21.2 1.3 0.1 0.0 0.0 0.1 68.6 2.1 3.8 22.2 23.6 0.8 4.8 0.0 0.1 0.0 0.1 5.7 0.6 7.2 6.9 4.2 0.0 1.6 1.3 3.6 0.1 0.1 3.6 0.7 1.4 1.8 9.5 0.0 0.3 0.6 8.2 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.1 4.9 11.8 0.0 4.8 1.0 2.9 2.3 3.6 0.4 0.2 0.0 15.0 0.6 0.0 0.0 0.0 0.3 0.0 30.9 9.8 0.0 0.0 0.5 0.0 0.0 0.4 1.0 0.0 4.2 22.4 0.0 0.0 1.9 0.0 1.0 1.4 0.5 0.1 0.0 3.7 0.0 1.1 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 4.4 5.2 3.0 1.7 3.4 7.1 4.9 5.7 3.8 4.8 7.2 0.3 0.0 0.0 0.0 0.4 1.8 2.8 1.9 0.0 0.1 0.2 0.3 0.6 21.5 3.8 1.8 0.0 0.0 0.0 123.6 0.0 15.5 0.0 1.2 1.0 0.5 4.8 0.0 0.8 25.8 0.1 1.1 60.1 0.5 0.0 4.1 0.7 5.7 0.2 16.8 0.7 20.8 0.0 0.0 1.1 0.3 0.0 0.4 0.0 1.0 0.6 0.2 1.0 0.0 5.8 26.9 94.9 0.0 0.4 3.4 113.1 0.0 4.5 0.5 0.0 3.1 1.8 0.3 0.2 0.0 1.1 0.1 0.5 3.6 18.7 19.7 PTTG1IP "C21orf1, C21orf3, PBF" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB034146: AB_1568894, HPA061827: AB_2684620" "unprognostic (1.78e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (5.24e-3)" "unprognostic (3.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (9.30e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.40e-4)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.90e-1)" 127.8 131.8 147.6 98.4 158.9 92.0 114.0 150.8 146.8 131.1 131.1 132.7 123.2 132.4 118.5 89.1 109.4 141.8 164.3 138.1 168.7 157.6 130.5 160.5 75.3 178.8 152.9 110.7 85.6 84.1 68.8 180.1 169.9 108.5 111.5 29.7 118.3 151.4 70.7 88.9 127.3 145.0 152.0 97.7 169.9 66.9 175.3 57.9 127.4 63.2 62.0 139.6 93.3 157.5 245.3 134.6 155.3 148.2 300.6 174.8 127.0 212.9 309.8 174.1 166.6 290.0 323.9 32.9 789.8 344.4 417.0 109.8 73.0 140.2 161.1 56.3 81.0 254.3 80.0 260.1 293.8 97.6 83.5 269.9 225.1 189.1 130.8 346.3 376.6 88.6 131.7 83.1 539.5 106.0 71.0 99.5 166.8 352.9 169.8 70.4 158.4 162.0 735.6 82.7 117.2 182.0 240.0 262.5 482.0 188.7 203.7 163.7 511.8 216.9 126.5 170.6 340.0 78.5 79.4 42.2 146.7 220.6 199.8 336.2 181.2 109.1 48.4 146.7 79.5 25.5 62.7 51.3 203.3 23.6 59.7 41.0 248.8 67.3 167.0 92.5 87.3 223.7 147.6 158.9 150.8 146.8 138.1 168.7 178.8 152.9 169.9 152.0 175.3 157.5 140.9 394.2 169.6 39.8 28.0 50.7 84.1 181.3 61.5 14.6 102.0 96.8 173.0 75.8 248.9 145.3 6.2 218.6 56.8 321.4 49.0 323.0 51.5 115.0 115.0 191.6 79.3 37.8 8.5 120.6 72.7 117.1 140.6 187.7 81.5 181.3 124.2 102.2 109.3 11.8 10.7 89.1 130.2 88.0 69.6 98.7 72.1 136.3 87.2 22.5 91.1 78.8 51.5 20.1 31.9 294.3 255.2 98.9 36.4 112.8 268.1 71.2 192.3 15.2 65.7 61.1 127.9 73.7 43.4 92.4 42.9 366.7 45.6 54.6 100.3 169.9 PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.8;Distal enterocytes: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 407.8;SK-MEL-30: 528.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 14000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031067: AB_2673722" "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.37e-4)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.43e-4)" 50.8 36.4 78.2 27.7 77.9 14.1 61.1 84.1 82.4 37.0 35.4 140.9 27.0 51.9 21.4 106.6 37.8 39.1 163.9 77.3 74.9 43.7 14.6 32.1 19.1 85.4 80.8 25.9 25.4 18.1 61.5 11.5 81.2 107.9 72.6 25.4 125.1 106.3 18.7 85.3 44.8 59.8 84.7 22.6 51.3 25.2 80.3 18.4 45.2 10.5 17.3 154.2 53.0 84.8 31.5 220.1 39.1 38.3 97.9 182.7 28.7 62.2 80.9 51.4 43.0 50.1 38.0 37.1 71.8 83.6 96.1 123.9 44.5 165.8 27.9 21.1 27.5 29.5 18.6 86.9 115.7 44.7 40.0 107.1 152.4 130.5 191.3 63.5 66.6 23.0 16.5 91.4 73.0 87.1 45.1 34.6 35.2 38.2 407.8 33.7 71.0 49.8 280.5 56.8 58.4 36.5 42.7 74.0 528.7 31.0 51.9 28.4 147.4 60.3 36.5 65.1 128.7 35.2 58.8 14.4 67.9 34.8 335.3 4.6 14.1 7.1 10.2 19.4 9.9 5.4 8.1 9.2 14.5 4.6 10.3 12.9 3.3 11.2 23.4 7.1 9.6 23.4 78.2 77.9 84.1 82.4 77.3 74.9 85.4 80.8 81.2 84.7 80.3 84.8 10.0 9.6 34.6 43.1 8.7 11.9 23.1 20.7 22.2 35.8 31.6 43.6 122.8 11.5 14.6 25.8 37.5 7.1 10.7 185.2 11.7 17.6 3.5 12.7 17.2 13.5 28.2 8.6 22.9 16.5 7.2 15.3 40.2 21.6 6.3 16.2 8.9 5.8 10.8 18.5 26.9 47.3 57.0 13.8 10.7 9.2 27.4 18.5 35.6 15.0 16.6 21.3 15.5 11.6 19.1 27.0 68.5 86.5 22.9 17.6 20.9 11.1 11.9 9.3 0.0 13.5 23.1 2.0 8.5 15.3 10.1 4.4 12.9 20.3 72.0 9.7 QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 260.9;Paneth cells: 224.5;Proximal enterocytes: 261.8;Undifferentiated cells: 280.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA042695: AB_2678119, HPA048651: AB_2680477, HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favorable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favorable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favorable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavorable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" 17.2 27.1 11.2 11.8 11.4 13.4 18.1 10.0 15.9 18.4 9.4 20.0 10.3 22.7 2.7 20.5 20.9 7.3 21.4 11.8 11.3 18.3 30.2 12.5 12.2 10.8 10.6 24.4 51.9 9.6 17.6 7.7 11.1 16.9 5.0 6.1 22.3 9.2 20.5 18.3 15.2 6.1 10.8 14.8 20.7 6.4 11.3 7.0 20.7 10.2 5.1 17.6 16.4 11.6 41.5 32.3 14.6 44.1 15.3 18.2 19.7 20.8 18.3 23.8 22.9 25.6 15.0 47.1 50.1 11.5 14.4 26.6 13.8 24.9 7.7 28.1 20.8 30.4 13.3 55.7 26.6 46.4 25.7 27.8 20.3 15.3 22.1 10.5 24.2 25.5 35.0 50.2 11.8 64.2 39.7 56.5 40.3 25.3 53.5 41.2 19.9 72.2 18.8 26.1 48.4 21.6 33.0 33.4 27.8 6.2 21.5 19.0 19.5 35.0 20.3 58.2 49.7 56.7 48.3 23.3 19.3 55.0 44.4 1.9 16.6 0.4 29.6 31.4 37.4 42.0 31.7 26.4 34.0 40.8 33.3 27.5 1.3 43.9 16.6 39.8 37.9 21.3 11.2 11.4 10.0 15.9 11.8 11.3 10.8 10.6 11.1 10.8 11.3 11.6 23.2 0.0 4.5 47.3 36.6 63.7 63.5 59.0 65.4 36.7 42.6 48.6 7.3 30.0 24.5 57.0 50.1 47.8 27.3 157.0 64.6 25.8 1.6 19.8 28.8 24.7 192.5 30.3 32.8 27.6 39.7 33.5 23.9 18.8 16.5 43.7 18.2 33.9 28.8 90.9 31.4 260.9 42.7 15.8 30.9 2.6 50.7 12.8 49.8 8.4 10.5 22.0 7.2 21.6 30.0 13.9 224.5 37.6 53.2 43.6 261.8 80.3 22.6 57.9 19.7 40.7 31.1 12.9 24.6 36.9 41.9 28.0 27.0 67.4 280.7 37.2 RAB1B ENSG00000174903 "RAB1B, member RAS oncogene family" Q9H0U4 11 66268590-66277492 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010225, HPA056141" Approved Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Endoplasmic reticulum" "CAB010225: AB_2284660, HPA056141: AB_2683051" "unprognostic (6.07e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-1)" "unprognostic (2.90e-1)" "unprognostic (9.91e-2)" "unprognostic (2.61e-2)" "unprognostic (2.04e-3)" "unprognostic (2.10e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-2)" "unprognostic (2.00e-1)" "prognostic favorable (1.09e-5)" "unprognostic (2.41e-2)" "unprognostic (9.45e-2)" "unprognostic (9.42e-2)" "unprognostic (5.85e-2)" 127.1 129.7 121.7 84.0 117.4 91.1 120.9 117.7 137.7 113.7 106.2 129.3 112.5 111.2 82.3 180.9 105.7 83.0 146.7 117.5 116.8 127.2 126.4 116.5 90.3 122.7 121.0 103.5 96.1 132.9 112.6 88.4 119.3 140.6 90.3 46.5 128.0 105.1 233.2 147.6 112.9 86.9 119.3 125.3 125.5 79.9 124.2 105.5 111.5 152.8 86.1 113.6 119.2 118.9 226.5 248.0 126.2 166.1 205.6 150.9 113.8 182.7 212.8 232.2 163.4 141.4 223.7 91.7 235.7 263.1 172.1 209.0 140.7 253.9 125.9 190.3 128.0 144.7 156.0 124.2 135.0 124.3 258.2 158.7 212.4 199.6 102.4 163.2 221.1 144.9 153.1 158.8 223.6 434.5 219.1 197.1 131.5 196.1 230.8 133.0 101.8 237.2 234.7 204.5 122.9 137.1 132.7 319.2 133.7 91.4 487.5 141.6 228.1 221.4 152.9 267.9 164.9 89.9 77.9 121.5 251.2 104.3 207.8 173.1 199.8 329.3 227.5 211.9 171.7 109.8 135.5 188.1 163.0 130.2 115.3 140.6 420.5 203.5 243.9 188.3 165.5 375.6 121.7 117.4 117.7 137.7 117.5 116.8 122.7 121.0 119.3 119.3 124.2 118.9 56.3 38.5 59.6 7.8 41.7 33.6 31.4 42.4 53.5 22.0 55.0 53.1 1.1 40.0 47.9 36.8 29.2 56.2 50.8 137.1 50.9 49.3 13.4 41.3 38.6 50.6 54.0 27.1 7.2 71.3 84.2 36.5 58.1 44.9 53.8 24.6 48.9 47.8 54.2 16.8 8.0 85.0 36.7 55.2 26.4 27.2 35.8 51.4 24.9 5.6 47.7 37.8 43.3 5.5 13.1 71.6 80.6 42.2 61.0 41.4 79.6 49.5 36.0 18.2 39.5 36.2 39.7 23.8 17.4 64.5 42.1 80.2 57.4 28.1 64.9 43.5 RAB4B "FLJ78649, MGC52123" ENSG00000167578 "RAB4B, member RAS oncogene family" P61018 19 40778216-40796942 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 80.4;Syncytiotrophoblasts: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (9.11e-3)" "unprognostic (2.67e-3)" "unprognostic (4.23e-3)" "unprognostic (4.02e-2)" "unprognostic (1.62e-1)" "unprognostic (4.73e-3)" "unprognostic (5.74e-2)" "unprognostic (7.93e-2)" "unprognostic (5.32e-1)" "unprognostic (2.46e-2)" "prognostic favorable (2.08e-4)" "unprognostic (7.73e-2)" "prognostic unfavorable (1.28e-4)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "prognostic favorable (1.99e-5)" 26.1 51.2 65.0 20.7 74.3 18.1 23.6 78.8 81.6 26.4 53.6 28.8 17.5 21.5 5.3 30.4 19.3 13.7 25.0 64.8 72.3 34.8 24.9 30.9 31.8 82.4 73.5 15.0 19.0 11.0 47.8 16.4 78.8 26.4 9.4 15.3 20.2 13.9 17.0 19.6 30.2 8.8 74.3 50.7 27.0 22.5 76.3 24.3 28.7 8.1 18.0 23.1 24.0 84.0 11.8 37.5 9.1 14.9 19.7 14.3 12.6 15.0 14.1 6.5 17.5 21.1 12.5 19.3 25.6 12.8 21.2 10.6 4.0 13.6 3.2 45.7 17.1 15.4 7.2 12.7 30.4 13.7 54.6 24.3 13.6 14.2 3.5 11.2 25.5 38.3 8.6 33.6 13.8 18.8 20.8 22.1 7.0 20.7 17.8 18.4 7.4 18.9 18.9 23.0 7.9 14.1 34.4 10.5 16.3 8.9 10.6 29.4 18.8 16.2 11.6 14.5 6.3 19.9 13.0 20.1 31.3 17.5 17.3 86.5 65.7 116.9 61.3 83.9 33.8 71.6 39.7 53.4 82.9 89.2 36.2 44.5 113.6 38.9 62.5 151.2 59.6 70.0 65.0 74.3 78.8 81.6 64.8 72.3 82.4 73.5 78.8 74.3 76.3 84.0 2.6 9.6 18.8 0.0 19.8 7.8 15.0 47.0 3.4 22.2 2.0 2.2 5.6 12.8 33.6 1.8 6.2 52.8 23.3 80.4 0.0 1.1 3.2 3.0 2.2 16.5 26.3 4.4 0.0 1.0 19.1 8.7 25.0 7.3 21.5 1.4 23.9 15.2 40.9 32.0 0.0 17.7 40.7 29.0 34.8 3.3 8.7 16.6 32.0 0.0 14.6 26.3 42.2 0.0 0.0 0.7 68.2 10.5 3.0 17.6 49.9 0.8 33.8 15.0 26.3 7.7 15.7 16.6 21.6 7.7 9.9 102.7 17.2 1.4 16.5 26.2 RABL6 "bA216L13.9, C9orf86, FLJ10101, FLJ13045, Parf, pp8875, RBEL1" ENSG00000196642 "RAB, member RAS oncogene family like 6" Q3YEC7 9 136807943-136841187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044037 Uncertain Approved Centrosome,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Centrosome "HPA044037: AB_10966437" "unprognostic (3.10e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "prognostic favorable (4.00e-4)" "unprognostic (9.23e-2)" "unprognostic (2.44e-2)" "unprognostic (1.90e-3)" "unprognostic (7.55e-3)" "unprognostic (1.65e-1)" "unprognostic (4.92e-2)" "prognostic favorable (1.46e-4)" "unprognostic (5.23e-2)" "unprognostic (1.03e-3)" "prognostic favorable (9.14e-4)" "unprognostic (4.08e-1)" "unprognostic (3.03e-2)" "unprognostic (2.15e-1)" 37.5 45.5 49.9 29.8 67.2 51.9 35.9 43.7 69.2 33.5 30.2 59.9 39.8 38.5 10.7 57.4 36.4 15.3 86.3 47.6 35.6 55.3 24.3 41.7 26.9 47.8 41.0 39.5 101.5 22.7 69.9 21.0 41.8 67.4 21.2 15.3 42.8 20.1 154.5 45.7 51.6 16.2 35.6 50.3 61.7 50.0 47.2 28.2 42.1 60.9 18.2 43.7 35.0 45.9 75.2 97.9 68.4 80.3 27.5 30.7 178.5 65.8 42.2 63.1 45.9 109.7 77.2 104.7 40.5 52.0 66.4 159.9 76.8 58.6 21.5 110.1 97.5 64.5 127.2 129.9 49.4 120.6 79.4 34.2 59.6 39.0 42.8 38.3 66.4 88.8 142.0 50.0 43.9 149.5 130.2 82.9 128.0 91.3 82.4 167.4 81.6 103.1 41.5 65.7 223.5 92.5 117.2 135.6 83.5 36.1 116.8 120.1 81.1 80.9 69.8 86.5 109.1 42.3 51.8 85.5 68.2 57.8 77.5 0.5 1.8 1.2 1.4 2.4 1.5 2.2 1.5 1.4 1.3 2.0 1.2 1.5 0.9 2.3 0.8 1.7 2.3 0.6 49.9 67.2 43.7 69.2 47.6 35.6 47.8 41.0 41.8 35.6 47.2 45.9 36.2 28.9 41.2 24.5 25.5 18.0 17.7 12.6 38.7 39.5 38.7 33.4 35.3 0.0 13.8 25.8 20.9 25.2 35.3 172.7 31.3 34.9 13.4 42.6 40.6 25.7 52.0 25.6 37.7 58.2 33.2 28.1 43.3 43.8 15.2 85.2 0.0 0.0 31.0 38.7 34.3 78.5 20.3 0.0 26.5 18.5 19.6 37.0 40.9 8.4 27.5 22.2 24.7 18.1 26.9 62.5 80.9 26.7 67.7 36.6 59.4 55.8 18.3 38.3 0.0 19.0 33.3 18.1 28.0 55.3 19.5 28.3 29.6 41.0 94.9 26.5 RAD9A RAD9 ENSG00000172613 "RAD9 checkpoint clamp component A" Q99638 11 67317871-67398410 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006725, HPA048155, CAB079979" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies" "CAB079979: , HPA006725: AB_1856041, HPA048155: AB_2680290" "unprognostic (7.64e-2)" "prognostic favorable (6.95e-4)" "unprognostic (8.83e-3)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (2.12e-3)" "unprognostic (9.64e-3)" "unprognostic (1.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (9.19e-2)" "unprognostic (2.50e-2)" "prognostic unfavorable (2.82e-5)" "unprognostic (6.16e-2)" "unprognostic (3.72e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.52e-6)" 5.8 5.0 3.3 6.9 3.6 10.2 6.9 2.1 6.0 9.2 2.9 7.3 10.9 7.4 2.1 9.0 10.9 5.7 4.2 3.8 2.4 7.1 6.6 6.7 8.3 2.9 3.6 8.0 8.0 3.4 10.1 4.4 2.2 10.8 3.0 1.8 9.8 6.1 5.2 11.4 11.1 2.4 2.2 9.4 8.4 8.6 2.5 6.1 9.7 2.1 3.7 6.5 8.5 2.2 10.8 15.8 9.5 13.8 2.8 1.1 12.0 5.7 4.9 8.0 7.1 23.2 20.9 11.1 12.4 1.8 13.0 18.7 6.0 5.5 0.9 13.0 16.3 16.8 8.5 10.4 3.8 12.3 20.3 3.2 5.3 7.2 3.5 6.1 5.5 23.2 14.7 15.6 2.3 33.2 21.9 21.8 13.2 15.9 12.1 18.8 12.5 13.6 2.2 9.0 9.8 10.6 9.9 27.2 21.1 2.4 19.1 10.9 4.2 11.7 14.3 23.3 8.7 14.6 14.2 11.5 7.5 11.6 9.6 5.3 1.8 6.0 5.2 2.3 3.8 4.3 4.1 4.3 1.2 3.1 2.9 3.2 2.8 3.1 2.5 3.4 2.4 1.5 3.3 3.6 2.1 6.0 3.8 2.4 2.9 3.6 2.2 2.2 2.5 2.2 16.0 22.4 17.1 10.1 31.0 17.1 17.7 17.9 23.3 19.6 19.7 18.4 1.1 12.8 22.2 20.2 70.9 27.9 31.3 54.2 13.7 11.3 27.3 32.1 13.4 16.3 14.3 17.7 8.5 13.1 22.4 13.8 27.0 14.9 20.3 26.0 11.0 6.6 15.1 21.9 6.0 48.9 10.2 10.3 31.4 13.2 10.5 14.0 19.6 11.2 8.9 15.0 56.7 2.5 5.3 11.6 31.6 12.4 38.5 16.6 61.8 10.9 44.0 32.1 13.1 10.5 14.5 32.0 17.6 18.3 17.3 40.6 30.3 15.3 38.7 18.0 RALB ENSG00000144118 "RAS like proto-oncogene B" P11234 2 120240064-120294710 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Cell division" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 335.7" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 378.4" "Group enriched" "Detected in all" 4 "granulocytes: 378.4;monocytes: 176.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026010, HPA065232" Enhanced NA NA 440000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026010: , HPA065232: AB_2685440" "unprognostic (5.16e-2)" "unprognostic (9.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.38e-2)" "unprognostic (3.89e-2)" "unprognostic (5.92e-3)" "unprognostic (1.77e-2)" "unprognostic (4.15e-2)" "unprognostic (4.91e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (2.29e-2)" "unprognostic (8.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" 53.8 35.9 30.6 57.2 30.8 60.0 39.9 32.8 38.7 44.3 33.1 59.2 50.5 37.5 15.8 73.3 45.7 44.8 51.0 32.3 37.7 56.5 34.2 50.7 35.8 30.8 33.6 28.7 25.6 335.7 16.6 63.1 30.6 51.0 51.8 25.8 36.2 31.7 30.1 25.7 44.8 46.5 31.3 54.2 39.3 29.9 37.9 27.5 30.8 43.9 35.0 51.0 49.1 32.8 179.8 47.7 46.8 29.5 71.2 115.5 66.7 121.4 105.8 93.3 70.5 99.4 118.0 7.1 63.9 131.6 88.2 64.1 22.5 93.1 85.7 293.3 25.8 84.4 36.3 71.3 46.0 45.1 144.9 60.3 99.0 97.2 74.0 77.1 272.9 6.3 66.5 28.1 108.2 91.9 5.9 100.0 31.7 71.6 101.9 1.2 59.3 38.1 97.5 45.6 13.3 32.1 50.4 137.9 85.1 39.3 43.3 66.3 168.4 91.1 69.8 93.9 48.8 16.2 9.1 12.8 72.7 57.5 95.6 101.8 80.9 230.5 19.0 117.7 18.5 45.0 18.0 19.0 65.4 59.6 11.9 13.7 378.4 25.5 176.1 6.9 24.6 59.5 30.6 30.8 32.8 38.7 32.3 37.7 30.8 33.6 30.6 31.3 37.9 32.8 69.3 9.6 27.0 6.5 23.8 19.4 30.1 22.4 7.4 4.1 23.2 7.9 55.8 18.6 21.9 11.0 12.5 6.0 11.8 95.3 66.5 84.9 18.8 28.4 22.8 77.8 18.6 8.4 12.9 55.0 128.5 32.7 17.9 26.7 106.1 90.6 78.5 9.8 53.6 13.5 9.7 19.1 18.3 54.3 59.4 23.0 19.9 66.7 35.6 16.9 62.6 26.3 21.6 10.1 5.4 138.1 62.1 31.2 6.7 28.5 44.6 104.4 46.3 7.5 19.7 18.3 33.4 13.1 16.2 16.4 18.9 36.7 19.5 12.9 31.3 32.2 RALY "HNRPCL2, P542" ENSG00000125970 "RALY heterogeneous nuclear ribonucleoprotein" Q9UKM9 20 33993646-34108308 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040971, HPA043614" Enhanced Enhanced Nucleoplasm,Vesicles NA NA 9400 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA040971: AB_2677230, HPA043614: AB_2678581" "unprognostic (2.06e-1)" "unprognostic (9.54e-3)" "unprognostic (3.72e-2)" "unprognostic (2.28e-1)" "unprognostic (4.68e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (3.06e-1)" "unprognostic (1.27e-1)" "unprognostic (3.66e-1)" "unprognostic (4.20e-2)" "unprognostic (8.59e-2)" "unprognostic (3.29e-2)" "unprognostic (2.88e-2)" "unprognostic (8.61e-3)" "unprognostic (1.64e-2)" "unprognostic (8.80e-2)" 109.7 65.4 72.1 90.4 83.2 189.2 98.2 82.6 79.3 108.9 81.8 127.2 109.8 96.9 41.6 119.6 84.8 70.7 143.2 67.6 77.4 104.4 68.3 117.4 116.9 87.8 81.9 101.2 78.2 62.1 55.6 77.6 84.2 88.3 87.6 55.0 105.3 64.3 178.4 114.6 117.7 70.1 83.7 109.6 101.9 116.5 80.9 161.7 125.5 106.0 99.9 99.3 98.4 100.7 250.4 138.1 247.6 193.9 115.3 110.3 210.1 172.9 136.0 215.1 183.0 375.8 204.0 204.3 238.7 140.6 290.9 259.4 135.8 252.7 119.2 132.2 119.3 468.3 81.4 375.4 147.8 236.2 215.0 122.4 141.6 161.9 175.4 160.7 203.0 245.6 201.7 300.9 135.8 185.9 589.3 266.6 137.5 306.0 277.2 344.4 360.6 250.7 126.7 135.4 235.8 266.6 271.8 248.4 376.6 125.8 256.2 234.4 167.5 414.4 270.7 212.3 206.6 310.7 308.3 353.5 213.0 169.9 201.3 139.3 110.7 221.3 138.8 137.1 100.2 96.5 122.2 150.4 135.3 99.6 107.8 104.0 173.3 186.1 195.5 110.0 141.4 165.3 72.1 83.2 82.6 79.3 67.6 77.4 87.8 81.9 84.2 83.7 80.9 100.7 91.8 54.5 61.3 23.2 98.3 79.2 126.9 102.3 74.6 24.2 74.9 67.8 63.4 58.6 61.7 55.2 18.8 161.3 118.3 287.4 127.2 149.1 48.1 36.4 48.5 92.1 93.0 87.9 19.3 160.5 227.7 78.2 70.8 66.9 59.7 69.7 76.8 39.8 159.6 8.4 14.6 143.2 95.6 112.2 118.1 46.7 65.6 96.9 115.6 50.6 151.3 62.6 163.7 15.6 57.1 190.3 270.7 62.1 206.4 157.5 220.7 107.3 38.8 36.3 111.7 47.7 97.7 106.6 121.1 103.7 80.7 171.4 117.2 51.6 178.6 176.2 RASSF6 ENSG00000169435 "Ras association domain family member 6" Q6ZTQ3 4 73571550-73620631 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.6;stomach 1: 34.9" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 120.3;Gastric mucus-secreting cells: 171.8;Ionocytes: 103.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 2.7" "Lineage enriched" "Detected in single" 13 "B-cells: 2.7" "Cell line enhanced" "Detected in some" "Daudi: 76.0;hTERT-HME1: 21.5;RPTEC TERT1: 23.5;RT4: 70.2;U-266/70: 20.2;U-698: 61.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA037712 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA037712: AB_2675625" "unprognostic (9.08e-3)" "unprognostic (1.23e-1)" "unprognostic (4.82e-2)" "unprognostic (3.09e-3)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (8.47e-2)" "unprognostic (2.05e-1)" "unprognostic (1.01e-1)" "unprognostic (3.11e-2)" "unprognostic (6.76e-2)" "unprognostic (3.89e-2)" "unprognostic (5.86e-2)" "unprognostic (2.95e-1)" "unprognostic (8.97e-3)" "unprognostic (5.03e-2)" 0.2 0.1 0.0 4.9 0.0 0.1 8.4 0.0 0.2 2.3 5.0 11.9 9.8 0.5 2.8 1.9 2.7 4.4 0.0 0.1 0.2 6.0 2.2 1.3 5.7 0.0 0.8 1.3 16.6 0.7 0.4 7.4 0.0 5.7 12.7 1.6 3.5 3.7 0.0 5.3 12.3 0.3 0.0 0.2 34.9 0.1 0.7 30.6 5.7 0.4 6.9 9.2 1.8 0.1 0.3 1.9 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 2.2 12.0 76.0 1.1 0.0 0.3 3.8 0.0 6.0 0.0 1.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 5.8 0.0 21.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 11.1 0.2 0.0 0.1 0.5 23.5 70.2 2.8 0.0 0.2 1.8 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 20.2 0.1 61.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.0 0.7 0.1 0.3 12.8 5.1 0.0 25.0 9.8 38.5 70.5 18.8 0.1 25.1 42.2 1.2 21.5 37.7 7.3 0.0 55.7 0.1 81.1 17.6 18.2 0.3 45.4 2.0 0.8 120.3 0.4 0.3 80.9 23.0 1.7 171.8 22.8 1.3 2.2 0.4 4.0 4.4 0.0 0.1 57.9 103.7 0.3 1.0 0.0 0.0 1.2 1.8 0.0 0.6 18.7 0.0 0.0 0.3 67.1 65.8 0.0 21.3 24.6 30.1 37.8 29.8 0.5 0.0 0.0 1.6 0.0 0.2 11.9 1.4 47.2 3.5 0.7 23.2 60.5 RASSF7 "C11orf13, CFAP88, FAP88, HRAS1, HRC1" ENSG00000099849 "Ras association domain family member 7" Q02833 11 560404-564025 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 127.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 224.6;Intestinal goblet cells: 179.2;Paneth cells: 194.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.5;HaCaT: 86.4;SK-BR-3: 75.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA078015 Supported "Centriolar satellite" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite" "HPA078015: AB_2686875" "unprognostic (1.11e-2)" "unprognostic (5.10e-2)" "unprognostic (1.75e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (1.13e-1)" "unprognostic (2.46e-3)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.60e-1)" "unprognostic (2.55e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.99e-1)" "unprognostic (2.83e-1)" "unprognostic (3.58e-3)" 15.6 5.0 7.1 8.5 9.4 6.5 13.8 10.1 10.4 23.4 6.8 50.5 33.6 6.3 15.8 49.2 50.9 10.8 4.9 7.3 7.1 127.5 92.8 44.6 10.7 9.3 6.5 6.6 67.5 6.4 27.4 5.0 9.9 42.6 8.5 1.6 42.5 11.5 1.6 53.5 43.5 1.0 6.4 17.7 63.5 13.2 7.1 8.7 23.3 0.6 5.6 18.6 23.7 6.3 51.7 49.9 2.3 12.8 0.0 0.0 35.2 7.7 5.9 8.0 5.9 52.6 85.5 6.6 34.6 4.2 14.0 86.4 7.3 26.5 1.2 8.9 25.6 4.6 28.0 25.9 5.3 10.8 7.4 0.1 25.5 2.7 2.4 11.0 4.8 13.4 11.7 2.5 0.7 51.7 12.2 23.1 7.1 58.2 28.1 19.2 3.7 14.8 39.2 24.8 10.9 8.4 5.4 75.7 6.6 4.0 34.0 6.9 6.6 1.6 23.5 3.1 15.0 8.6 9.9 5.3 12.8 15.1 6.9 5.2 6.0 23.0 17.7 5.2 16.1 13.6 18.3 15.9 10.5 14.8 14.8 13.2 7.3 8.3 5.7 18.7 21.9 8.9 7.1 9.4 10.1 10.4 7.3 7.1 9.3 6.5 9.9 6.4 7.1 6.3 6.5 86.6 70.0 3.3 19.1 25.4 23.4 118.1 14.2 2.7 39.2 30.6 4.7 92.9 90.4 86.5 0.0 38.9 20.9 224.6 52.8 90.7 17.2 28.8 3.9 8.5 51.0 14.5 5.5 90.5 111.7 5.9 124.4 35.2 15.2 15.5 7.9 73.3 19.9 11.8 2.6 179.2 46.8 11.2 15.7 23.0 2.5 11.5 5.4 1.0 28.7 7.9 21.6 1.5 0.6 148.1 194.4 0.4 12.3 61.8 110.0 44.7 73.4 3.2 0.0 0.3 6.7 4.6 9.7 21.2 25.7 40.5 29.7 4.3 113.1 60.3 RAVER2 "FLJ10770, KIAA1579" ENSG00000162437 "Ribonucleoprotein, PTB binding 2" Q9HCJ3 1 64745095-64833232 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Distal enterocytes: 60.1;Inhibitory neurons: 40.4;Oligodendrocyte precursor cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "basophil: 6.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045785 Approved Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA045785: AB_10964058" "unprognostic (8.02e-2)" "unprognostic (5.23e-2)" "unprognostic (4.23e-3)" "unprognostic (2.73e-1)" "unprognostic (2.32e-1)" "unprognostic (2.89e-2)" "unprognostic (2.22e-3)" "unprognostic (1.23e-2)" "unprognostic (3.14e-1)" "unprognostic (1.47e-1)" "unprognostic (6.56e-2)" "unprognostic (1.09e-1)" "prognostic favorable (5.14e-6)" "unprognostic (1.74e-1)" "unprognostic (3.50e-2)" "unprognostic (1.41e-1)" "unprognostic (5.09e-2)" 4.7 8.2 12.8 4.2 12.1 9.5 8.2 15.0 12.4 7.7 12.6 23.6 24.2 7.8 5.7 9.4 7.5 11.3 12.6 13.3 10.9 7.7 1.6 8.3 2.0 9.7 12.2 6.4 7.3 16.2 12.3 7.3 10.3 12.0 26.8 15.1 15.5 10.3 22.2 6.7 26.1 9.3 10.4 4.3 12.5 2.7 13.3 8.3 6.1 17.7 4.1 6.5 7.4 9.3 16.7 5.1 15.2 16.7 2.7 2.3 4.1 3.6 6.5 7.3 8.2 13.6 7.3 0.1 8.2 3.8 16.6 12.4 15.7 10.9 8.9 0.1 17.3 20.2 13.7 12.2 5.1 27.5 0.2 6.8 9.8 0.5 7.5 16.9 12.2 16.6 4.5 16.3 0.6 6.2 9.2 5.6 18.8 13.1 13.3 31.1 23.9 6.7 8.0 12.3 11.5 25.6 16.4 0.0 16.0 14.3 12.6 4.3 4.6 6.8 10.9 6.8 13.1 12.3 14.9 7.0 4.1 0.1 6.4 6.2 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 12.8 12.1 15.0 12.4 13.3 10.9 9.7 12.2 10.3 10.4 13.3 9.3 9.2 6.4 13.5 72.8 0.6 8.0 7.0 3.9 8.0 7.1 7.2 6.0 24.4 11.5 8.3 1.8 14.6 0.2 1.1 60.1 0.0 3.4 9.8 5.7 2.5 10.6 18.0 4.2 29.0 5.2 0.3 6.3 11.2 6.5 1.3 7.1 6.8 0.3 0.6 0.0 40.4 30.7 4.1 4.8 3.3 16.8 6.5 2.0 3.6 22.5 0.3 26.1 0.0 40.2 1.8 2.7 20.5 8.2 2.3 6.6 26.9 2.1 6.1 3.7 0.0 6.2 5.5 3.1 3.2 8.5 5.8 0.3 1.5 1.7 27.8 7.3 RBCK1 "C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4" ENSG00000125826 "RANBP2-type and C3HC4-type zinc finger containing 1" Q9BYM8 20 407498-432139 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 255.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.94e-2)" "unprognostic (2.50e-1)" "unprognostic (1.62e-2)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.92e-1)" "unprognostic (1.54e-3)" "unprognostic (1.15e-2)" "unprognostic (7.89e-2)" "unprognostic (3.44e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-2)" "prognostic unfavorable (7.41e-9)" "unprognostic (5.87e-2)" "unprognostic (3.64e-2)" "unprognostic (3.33e-2)" "unprognostic (2.39e-3)" 41.3 68.6 20.4 28.8 23.3 25.7 38.6 26.6 32.3 48.5 16.9 50.2 34.6 47.0 13.9 55.0 44.7 19.4 41.3 20.2 20.8 52.5 108.9 47.7 28.1 27.9 22.1 53.5 55.3 30.1 64.1 22.8 23.9 56.0 17.7 12.2 41.9 26.3 38.6 43.0 56.8 19.2 20.3 66.2 50.3 34.8 22.0 43.7 46.7 18.2 18.0 45.6 46.8 27.6 64.0 88.4 21.9 37.2 44.3 54.7 44.9 34.2 55.0 56.2 73.4 53.7 74.1 29.2 51.3 70.7 103.5 62.7 29.4 151.0 19.0 21.7 29.8 30.2 23.9 140.9 185.3 28.4 21.5 83.1 255.7 43.0 173.2 68.2 50.8 109.8 29.6 55.0 40.7 33.2 61.5 69.9 18.4 77.4 73.0 40.3 21.8 37.3 72.7 57.5 41.3 35.9 24.1 122.4 140.7 25.0 73.3 64.2 31.0 54.5 27.0 33.2 46.5 44.4 61.6 35.6 24.5 61.4 39.0 56.5 48.8 85.4 61.9 71.3 43.5 48.1 48.0 63.1 43.6 46.8 38.7 45.2 135.6 52.4 83.9 72.1 55.7 52.7 20.4 23.3 26.6 32.3 20.2 20.8 27.9 22.1 23.9 20.3 22.0 27.6 69.4 32.1 39.8 40.8 54.4 44.5 77.1 96.2 49.5 15.3 65.4 66.7 19.9 64.3 48.2 57.0 16.7 88.7 72.6 111.4 62.6 111.7 58.9 40.4 45.3 59.3 61.7 43.8 15.8 116.2 102.4 52.3 50.0 54.3 43.8 62.9 57.1 139.3 66.8 16.8 17.8 122.8 46.8 69.8 44.2 163.3 65.9 57.2 42.7 23.4 69.1 45.1 106.1 22.1 24.3 108.5 161.0 47.8 30.5 98.8 185.2 74.5 39.0 29.0 46.0 56.9 51.9 32.6 29.3 69.0 40.2 94.7 71.0 110.6 74.2 120.3 RBM10 "DXS8237E, GPATC9, GPATCH9, KIAA0122, S1-1, ZRANB5" ENSG00000182872 "RNA binding motif protein 10" P98175 X 47145221-47186813 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034972, HPA057372" Approved Enhanced "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA034972: AB_10602919, HPA057372: AB_2683421" "unprognostic (9.07e-2)" "prognostic favorable (6.71e-4)" "unprognostic (7.83e-2)" "unprognostic (1.61e-2)" "unprognostic (1.86e-1)" "unprognostic (3.04e-2)" "unprognostic (4.47e-3)" "unprognostic (8.11e-2)" "unprognostic (9.86e-3)" "unprognostic (1.76e-1)" "prognostic favorable (2.86e-6)" "unprognostic (1.18e-1)" "unprognostic (6.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.40e-2)" "unprognostic (1.20e-3)" 23.7 31.1 28.5 19.9 28.8 32.5 23.9 32.6 36.4 33.3 26.6 28.8 18.1 29.5 12.4 34.2 31.5 12.1 30.8 28.5 28.4 30.0 32.2 23.9 25.1 28.2 27.9 40.6 32.2 15.9 38.0 17.3 28.3 33.8 11.3 14.8 23.6 15.6 26.5 27.1 27.8 12.5 26.6 33.9 26.4 12.8 29.3 23.6 33.1 12.4 15.9 28.3 29.9 31.9 50.1 52.5 48.9 58.8 25.7 21.0 57.3 36.8 21.4 37.2 35.8 46.4 39.8 60.1 22.0 25.6 47.5 47.7 64.9 46.1 20.4 61.6 59.0 45.1 65.1 48.8 37.5 46.0 52.1 27.7 22.0 61.2 49.8 26.5 40.4 56.5 38.3 47.0 23.0 74.9 84.8 78.2 81.9 37.1 58.0 74.0 41.0 62.2 27.7 42.9 58.6 44.5 56.0 41.6 35.6 29.3 50.9 45.7 35.8 43.7 54.9 47.8 39.5 48.4 42.9 49.5 38.8 32.8 62.3 13.5 8.1 11.4 12.7 10.7 12.0 11.2 10.2 10.8 9.2 11.1 10.0 9.7 7.5 9.9 15.8 10.7 12.7 9.3 28.5 28.8 32.6 36.4 28.5 28.4 28.2 27.9 28.3 26.6 29.3 31.9 17.4 41.7 36.9 22.5 21.6 11.1 22.4 15.0 22.8 26.7 16.5 16.8 36.6 21.5 28.8 9.2 14.6 34.2 21.3 32.2 11.7 20.5 1.3 23.6 20.1 19.6 35.8 14.9 14.8 17.7 28.5 20.2 31.6 31.5 24.1 29.1 16.8 23.3 19.7 21.9 15.4 31.5 10.2 14.2 10.0 2.7 18.0 15.4 16.0 8.4 19.9 14.7 20.6 15.1 18.1 19.8 20.8 25.6 22.5 18.7 23.1 14.3 28.8 27.0 0.0 21.4 21.8 10.7 8.7 23.4 10.5 46.1 23.8 19.7 34.2 18.1 RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 442.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 136.2" "Group enriched" "Detected in many" 12 "dendritic cells: 34.4;granulocytes: 136.2;monocytes: 45.5" "Cell line enhanced" "Detected in many" "BEWO: 134.0;CAPAN-2: 63.5;OE19: 56.7;SK-BR-3: 58.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" 9.3 49.7 2.2 20.3 1.9 9.6 24.7 1.8 3.0 15.3 44.9 61.0 68.4 3.5 23.1 42.2 17.7 17.9 1.3 2.8 2.3 67.6 34.5 21.0 8.2 6.0 3.2 2.2 25.9 27.8 3.2 20.1 4.9 33.2 50.5 0.4 59.4 13.4 0.5 9.0 64.1 4.7 4.1 14.7 64.6 6.7 5.7 4.4 49.5 1.1 11.4 22.6 15.5 6.8 31.9 47.8 0.0 1.8 0.2 0.0 134.0 0.8 1.6 0.1 0.6 28.3 63.5 0.2 23.0 1.2 3.8 14.2 0.9 11.8 0.3 0.2 7.6 0.0 3.1 7.9 0.6 0.3 0.3 0.8 6.0 0.1 0.1 1.8 0.0 0.0 1.8 7.0 0.1 18.1 0.2 1.1 13.5 56.7 2.4 0.2 0.0 34.7 46.8 41.6 1.6 0.3 17.3 58.4 0.3 14.8 23.9 9.0 0.0 0.5 1.9 0.3 1.0 23.5 37.7 4.1 5.0 3.9 0.2 0.5 45.5 0.5 0.2 33.1 0.3 5.9 0.2 0.1 34.4 5.4 0.4 0.1 136.2 0.5 26.2 14.1 0.2 16.9 2.2 1.9 1.8 3.0 2.8 2.3 6.0 3.2 4.9 4.1 5.7 6.8 1.1 80.1 116.6 0.7 21.2 58.9 75.2 42.9 95.0 0.1 145.7 63.5 1.9 75.8 92.2 112.2 0.0 99.6 16.3 442.8 64.6 90.6 1.3 132.6 9.5 6.0 121.9 2.5 2.5 115.4 84.3 7.7 174.8 143.7 7.0 8.7 23.6 140.4 92.6 1.7 1.9 234.2 59.0 138.8 92.8 2.6 2.5 119.9 37.4 82.4 80.6 0.3 1.0 2.5 0.8 108.0 228.1 1.2 40.1 164.7 218.1 143.6 118.3 0.1 0.0 1.4 5.1 2.6 10.4 178.1 75.4 262.6 4.8 16.9 203.8 295.4 REPIN1 "AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464" ENSG00000214022 "Replication initiator 1" Q9BWE0 7 150368189-150374044 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 7.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 246.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036022 Approved Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA036022: AB_10610417" "unprognostic (2.73e-1)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "unprognostic (7.50e-3)" "unprognostic (5.42e-2)" "unprognostic (7.00e-3)" "unprognostic (1.52e-2)" "unprognostic (6.88e-3)" "unprognostic (6.68e-2)" "unprognostic (6.59e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.40e-2)" "prognostic favorable (5.56e-4)" "prognostic favorable (1.61e-4)" "unprognostic (1.79e-1)" "unprognostic (2.02e-3)" "prognostic favorable (6.41e-4)" 28.7 77.2 45.1 25.2 43.6 44.1 35.1 43.1 46.4 31.7 54.6 68.4 42.2 37.5 31.8 37.4 40.9 14.6 65.3 37.9 40.0 51.5 86.6 31.7 35.7 52.3 46.7 37.3 67.7 35.5 69.7 12.1 45.5 49.2 28.3 23.7 41.7 23.9 134.5 31.8 56.5 15.4 41.1 56.2 53.1 18.2 49.5 41.0 45.0 66.2 24.8 42.5 25.0 42.1 59.4 71.3 66.1 81.5 15.8 11.3 40.2 28.7 35.2 27.6 23.8 55.5 37.6 65.5 70.9 20.6 48.0 43.4 36.4 11.4 13.9 72.0 54.8 38.4 40.3 70.4 52.3 68.4 60.1 14.7 34.1 15.2 3.5 26.1 39.4 39.1 93.5 39.9 23.1 76.7 95.1 77.4 69.5 39.7 69.9 51.8 76.4 246.3 29.4 103.7 96.9 123.7 43.3 107.5 75.8 27.2 52.8 54.2 42.1 21.2 17.4 23.6 58.7 115.4 46.1 59.8 37.1 59.9 53.3 0.0 1.4 2.7 0.8 0.7 1.3 2.5 1.8 1.5 2.2 2.4 2.3 1.1 1.4 1.8 0.3 7.8 0.8 0.9 45.1 43.6 43.1 46.4 37.9 40.0 52.3 46.7 45.5 41.1 49.5 42.1 21.1 35.3 18.6 17.9 26.9 9.4 18.3 11.5 14.8 57.9 39.3 33.1 46.5 45.8 15.0 14.7 41.7 28.0 49.5 53.7 62.6 37.3 7.8 53.4 14.3 24.3 68.1 14.5 13.0 50.3 12.9 16.1 23.4 35.8 24.7 56.3 26.0 69.7 32.0 80.8 15.8 68.6 32.6 14.8 23.9 9.8 22.1 21.8 16.0 9.4 88.4 101.3 40.2 17.6 16.6 34.3 37.1 19.9 26.4 31.6 47.0 32.8 36.2 55.8 6.6 28.0 20.1 10.2 3.1 17.6 17.8 25.6 16.0 33.5 109.7 19.9 RFK "FLJ11149, RIFK" ENSG00000135002 "Riboflavin kinase" Q969G6 9 76385526-76394517 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.0;Pancreatic endocrine cells: 220.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023259, CAB033887, HPA057163" Approved Approved "Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB033887: AB_2178617, HPA023259: AB_2671127, HPA057163: AB_2683357" "unprognostic (1.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-3)" "unprognostic (8.61e-3)" "unprognostic (3.11e-1)" "unprognostic (1.39e-1)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (4.61e-2)" "unprognostic (1.22e-3)" "unprognostic (3.22e-2)" "unprognostic (1.83e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" 11.6 20.6 18.0 14.6 18.4 25.0 11.7 12.6 21.1 11.7 12.5 30.8 33.1 12.8 18.2 12.9 13.6 19.9 16.3 20.6 27.2 27.0 29.2 12.4 11.6 16.9 18.4 11.7 16.4 23.8 12.0 13.2 27.0 13.0 22.9 14.7 11.0 9.9 14.9 5.1 28.2 11.9 14.2 10.2 29.0 16.7 21.6 12.0 19.7 18.7 11.2 13.9 5.9 13.5 21.9 23.2 13.9 18.1 20.5 20.3 41.8 25.2 18.6 17.8 13.9 8.2 13.3 35.3 28.7 18.2 32.3 22.9 19.3 16.5 35.3 10.4 18.0 11.2 30.4 26.2 36.7 37.9 25.6 13.5 29.3 21.4 23.2 19.9 58.3 30.4 30.6 28.7 36.1 20.8 49.3 13.3 18.1 51.2 22.7 26.7 18.3 8.9 82.0 10.6 35.0 12.7 26.9 37.2 22.9 18.1 9.4 20.2 35.9 18.5 33.3 40.1 35.6 30.7 32.3 12.4 30.7 33.3 25.9 5.2 9.8 3.6 5.0 19.9 7.5 5.8 7.3 6.0 11.8 4.4 7.0 6.7 1.4 8.5 21.1 4.3 7.4 9.8 18.0 18.4 12.6 21.1 20.6 27.2 16.9 18.4 27.0 14.2 21.6 13.5 27.3 16.0 9.2 5.9 22.9 45.4 23.8 15.3 22.2 50.4 24.5 20.6 37.9 34.3 20.1 42.3 20.9 54.1 18.4 158.8 60.7 64.9 191.7 37.8 18.5 46.2 28.2 48.8 18.0 189.3 352.0 33.5 33.1 42.3 12.0 18.0 124.2 40.9 33.2 11.8 19.3 23.1 40.7 57.6 26.6 118.1 22.1 29.9 30.2 10.3 25.2 44.7 9.2 7.1 6.5 220.6 68.3 65.1 12.7 33.6 79.9 142.8 27.7 28.7 0.0 23.0 21.7 91.8 64.1 18.8 40.5 123.5 23.1 18.8 33.7 22.6 RGMB "DRAGON, FLJ90406" ENSG00000174136 "Repulsive guidance molecule BMP co-receptor b" Q6NW40 5 98768650-98798643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.9;Undifferentiated cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 3.3" "Group enriched" "Detected in many" 12 "B-cells: 1.6;T-cells: 3.3" "Cell line enhanced" "Detected in many" "BJ: 285.8;BJ hTERT+: 142.9;fHDF/TERT166: 178.0;HBF TERT88: 222.5;LHCN-M2: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016993 Approved Nucleoplasm NA NA 560000 "Cluster 32: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA016993: AB_1856216" "unprognostic (1.50e-2)" "unprognostic (3.77e-2)" "unprognostic (9.03e-2)" "unprognostic (8.92e-2)" "unprognostic (2.88e-1)" "unprognostic (5.27e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (8.24e-2)" "unprognostic (2.19e-1)" "unprognostic (3.60e-3)" "unprognostic (9.00e-2)" "unprognostic (3.88e-2)" "unprognostic (3.90e-2)" "unprognostic (6.40e-2)" "unprognostic (4.20e-2)" "unprognostic (3.78e-3)" 8.8 7.7 14.8 7.2 18.4 0.3 9.1 11.4 17.4 9.3 5.7 20.5 21.4 9.2 6.0 11.8 11.1 7.5 10.2 17.4 15.1 4.7 6.0 8.1 3.7 12.9 16.0 21.8 11.2 9.3 11.4 5.5 27.1 20.7 33.3 3.8 21.8 13.9 24.8 33.8 26.2 10.9 12.2 6.0 41.7 10.5 22.3 2.6 11.5 16.1 4.5 10.8 9.5 14.9 7.3 5.2 87.8 8.1 26.2 44.5 9.1 285.8 142.9 138.5 97.6 4.4 3.5 4.2 10.2 178.0 9.7 7.5 10.4 26.0 222.5 12.5 10.2 0.0 7.1 4.9 12.6 0.9 0.1 37.1 9.4 71.1 28.2 37.6 26.3 13.6 0.0 3.5 167.1 8.1 0.1 0.1 6.0 3.3 14.0 11.4 50.7 7.9 5.4 8.4 35.6 18.0 3.9 9.4 14.1 4.4 7.5 0.4 57.4 86.7 14.2 54.1 133.5 6.0 9.1 5.8 31.9 0.1 19.1 0.0 0.0 0.2 0.1 0.0 0.7 1.1 1.5 0.6 0.0 1.6 3.3 1.5 0.1 0.1 0.0 0.0 2.4 0.8 14.8 18.4 11.4 17.4 17.4 15.1 12.9 16.0 27.1 12.2 22.3 14.9 8.6 16.0 4.1 7.5 12.7 31.0 15.3 6.0 44.3 5.7 17.8 12.4 14.3 7.2 5.3 9.2 16.7 4.5 0.4 12.8 1.9 5.0 63.9 10.2 12.7 10.3 21.8 0.0 20.8 5.3 6.2 19.1 18.8 18.0 0.0 4.0 9.3 8.2 2.1 0.0 23.6 44.6 4.1 1.0 7.2 16.9 9.0 2.4 12.4 5.6 0.7 1.7 0.0 35.2 6.6 8.4 16.3 7.2 1.7 16.1 11.9 1.6 6.1 4.0 0.0 20.3 13.1 7.4 17.5 27.0 24.4 1.8 2.9 5.4 88.9 17.4 RHOF "ARHF, FLJ20247, RIF" ENSG00000139725 "Ras homolog family member F, filopodia associated" Q9HBH0 12 121777754-121803403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 273.9;Langerhans cells: 224.9;monocytes: 241.2;Pancreatic endocrine cells: 191.7;Paneth cells: 279.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 129.0;HDLM-2: 177.1;PC-3: 147.3;RPTEC TERT1: 127.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045912, HPA076019" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA045912: , HPA076019: AB_2732299" "unprognostic (1.26e-1)" "unprognostic (8.73e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-5)" "unprognostic (1.38e-3)" "unprognostic (2.37e-4)" "unprognostic (1.34e-1)" "unprognostic (5.51e-2)" "unprognostic (1.10e-4)" "unprognostic (1.10e-1)" "unprognostic (5.01e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-2)" "unprognostic (7.51e-4)" "unprognostic (1.14e-1)" 6.5 13.3 11.5 26.6 9.9 47.4 5.5 21.6 12.0 14.3 10.6 24.3 31.8 13.2 21.8 11.7 10.0 9.8 15.0 10.4 11.0 16.2 3.9 20.6 41.0 13.0 12.2 8.9 6.1 7.7 5.1 5.7 13.4 9.2 19.3 9.9 11.5 9.8 11.8 9.2 32.3 11.5 8.7 33.3 28.2 9.0 10.6 25.6 14.6 2.8 31.4 9.1 7.3 11.7 58.3 69.2 12.4 15.3 4.4 6.4 5.6 5.3 5.2 2.5 4.4 28.8 129.0 6.3 42.6 6.0 1.4 8.6 23.2 33.7 2.2 177.1 8.0 37.9 47.5 27.7 10.1 38.6 25.8 9.0 7.5 5.4 2.9 23.8 17.6 44.7 5.6 9.9 1.4 41.7 50.7 56.7 10.4 13.6 147.3 26.5 0.7 10.8 127.9 4.9 9.9 9.4 38.5 4.5 2.6 5.6 19.9 15.0 21.4 4.0 40.1 12.5 1.5 12.3 7.6 20.0 5.0 42.9 2.6 23.8 10.9 41.5 97.0 36.5 92.7 55.5 77.2 82.5 31.0 45.2 59.5 73.2 24.4 61.4 69.8 74.3 90.2 43.3 11.5 9.9 21.6 12.0 10.4 11.0 13.0 12.2 13.4 8.7 10.6 11.7 3.1 38.5 10.7 1.0 54.1 8.7 1.9 5.5 3.4 8.1 9.3 3.8 1.5 15.7 11.3 23.9 0.0 2.7 111.8 273.9 41.1 34.0 20.2 16.5 5.6 3.5 6.7 12.2 5.3 55.3 3.9 5.3 50.4 37.1 20.8 13.1 10.0 4.0 14.4 0.0 3.9 28.6 2.0 10.9 224.9 53.8 4.1 40.3 21.4 3.7 241.2 4.7 103.0 1.0 1.2 191.7 279.6 2.2 39.4 3.8 121.6 15.1 13.5 9.7 6.6 2.6 4.5 17.7 2.9 2.5 13.2 5.5 99.2 23.4 17.3 44.3 RILP FLJ31193 ENSG00000167705 "Rab interacting lysosomal protein" Q96NA2 17 1646145-1649866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.5;skeletal muscle: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.4;Proximal enterocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.5;eosinophil: 1.0;intermediate monocyte: 1.2;myeloid DC: 2.4;neutrophil: 3.3;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.3;monocytes: 3.5" "Cell line enhanced" "Detected in many" "HEL: 40.6;HMC-1: 19.5;K-562: 15.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 18000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" "prognostic favorable (7.97e-4)" "unprognostic (7.93e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-2)" "unprognostic (8.84e-3)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "prognostic favorable (8.51e-5)" "unprognostic (2.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.00e-1)" "prognostic favorable (7.12e-4)" 17.4 18.0 3.4 0.8 3.3 8.1 15.6 3.2 5.1 5.0 10.7 15.5 10.5 5.9 0.6 5.4 6.9 1.1 60.5 3.1 3.3 15.3 29.1 13.1 1.0 3.7 3.4 3.2 10.4 1.8 4.5 0.8 3.4 6.0 1.4 0.4 11.5 1.2 48.1 6.3 13.0 0.9 2.9 15.1 13.5 3.2 3.8 0.3 29.6 8.3 0.4 11.3 5.1 3.2 2.3 1.6 0.2 1.7 1.1 2.7 7.7 1.5 1.0 1.6 0.9 3.6 0.5 0.4 5.2 1.2 0.5 5.5 0.2 0.2 0.3 0.2 3.6 40.6 0.5 4.6 1.7 0.3 19.5 2.2 0.7 0.4 0.0 0.8 1.4 0.3 15.8 0.4 0.5 2.2 1.4 3.1 0.4 0.4 8.1 5.8 0.0 1.1 0.0 1.3 0.1 0.6 0.8 1.0 2.0 0.2 1.0 0.3 7.8 0.5 1.0 1.9 1.5 0.3 0.5 0.0 3.0 1.8 0.3 0.3 3.5 1.0 0.1 1.2 0.1 0.3 0.2 0.1 2.4 0.0 0.2 0.0 3.3 0.5 0.2 1.3 0.1 0.7 3.4 3.3 3.2 5.1 3.1 3.3 3.7 3.4 3.4 2.9 3.8 3.2 42.6 19.2 17.7 3.3 3.2 8.8 13.3 7.5 2.8 1.6 11.1 13.1 59.9 17.2 8.9 7.3 0.0 15.8 12.1 101.4 50.9 29.2 0.1 3.2 5.1 21.9 3.0 65.9 3.1 25.4 9.4 12.9 24.5 5.1 0.0 2.1 26.0 30.6 57.1 3.3 2.4 27.6 8.2 35.2 34.3 2.6 6.8 34.1 14.2 5.6 28.1 9.9 5.2 2.0 1.3 20.2 59.7 8.2 10.3 8.4 84.9 20.8 3.1 1.3 13.1 8.3 9.2 0.6 12.2 7.4 8.2 34.6 5.2 9.4 28.7 21.0 RIMKLA "FAM80A, MGC47816, NAAGS-II, RP11-157D18.1" ENSG00000177181 "Ribosomal modification protein rimK like family member A" Q8IXN7 1 42380792-42424232 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.0;retina: 11.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.9;Cone photoreceptor cells: 43.8;Distal enterocytes: 46.3;Excitatory neurons: 39.1;Horizontal cells: 35.3;Inhibitory neurons: 35.9;Rod photoreceptor cells: 24.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.4;JURKAT: 5.8;Karpas-707: 8.3;SCLC-21H: 9.9;U-266/70: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027826 Uncertain Uncertain "Nucleoli fibrillar center" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" "HPA027826: AB_10603992" "unprognostic (4.04e-2)" "unprognostic (1.61e-1)" "unprognostic (3.68e-3)" "unprognostic (9.84e-2)" "unprognostic (2.49e-2)" "unprognostic (1.06e-1)" "unprognostic (2.63e-3)" "prognostic favorable (1.43e-4)" "unprognostic (8.89e-2)" "unprognostic (3.76e-1)" "unprognostic (9.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" "unprognostic (7.07e-2)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" 0.2 0.2 2.9 0.4 3.6 0.0 0.2 3.7 15.0 0.1 0.0 3.0 0.3 0.1 0.0 0.1 0.2 0.5 3.2 4.5 2.3 0.8 0.1 1.9 0.1 5.7 2.2 0.0 1.0 2.2 1.2 0.2 6.2 0.5 3.2 11.2 0.5 0.2 0.7 0.2 0.4 0.6 1.2 0.2 1.0 0.7 6.2 0.0 0.6 1.0 0.0 0.4 0.2 6.3 0.0 0.7 0.1 6.4 0.1 0.0 1.3 0.0 0.0 0.2 0.5 0.3 0.2 0.0 1.4 0.0 1.2 0.0 4.2 0.0 0.3 3.7 2.5 0.3 0.1 1.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 8.3 0.0 0.3 2.0 0.0 3.5 0.5 5.1 0.0 0.2 0.3 0.6 1.7 9.9 4.2 0.3 0.3 0.1 0.7 0.3 1.9 0.0 0.0 0.4 0.0 0.7 7.4 4.4 5.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 2.9 3.6 3.7 15.0 4.5 2.3 5.7 2.2 6.2 1.2 6.2 6.3 0.9 16.0 3.9 1.3 0.2 0.6 1.1 1.0 0.0 25.9 0.9 1.0 14.4 1.5 1.1 1.8 43.8 1.4 0.3 46.3 1.9 3.3 5.3 0.4 0.0 2.2 11.4 0.0 39.1 4.8 20.1 0.5 0.5 0.1 0.0 0.3 0.7 0.0 1.0 35.3 35.9 8.0 2.0 0.3 1.4 10.5 0.3 0.3 5.4 2.8 0.0 5.1 0.0 7.1 3.9 9.4 14.2 0.0 0.1 1.7 0.3 3.7 0.2 24.6 0.0 0.8 0.6 1.1 4.8 0.0 0.1 1.6 0.7 0.3 5.2 1.0 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23453287-23486603 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 174.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 338.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavorable (4.10e-4)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 23.1 18.5 5.5 20.4 7.1 174.3 19.2 7.9 10.2 17.4 8.3 47.5 51.6 16.7 12.4 65.5 14.8 24.3 32.7 5.9 6.7 29.6 55.6 22.7 22.8 9.3 7.3 15.7 27.6 22.8 5.4 34.9 8.9 20.1 43.5 19.6 23.2 14.5 52.9 33.3 62.5 19.7 7.5 21.5 38.5 36.6 6.9 21.5 22.2 48.8 30.2 25.8 27.0 10.6 41.9 15.7 17.8 25.0 31.8 37.7 28.5 38.9 29.8 27.6 28.4 17.3 47.5 27.6 52.3 43.7 26.9 57.6 25.9 45.4 38.9 29.5 12.0 25.9 26.9 22.2 71.7 74.7 25.8 39.0 91.2 44.1 66.7 36.7 38.4 19.2 39.8 34.7 45.0 19.4 25.8 15.6 17.6 59.0 31.3 31.3 33.2 41.2 39.3 50.0 39.5 28.9 50.1 28.4 37.4 41.0 21.9 45.0 63.7 48.4 10.9 21.2 28.9 66.1 56.0 38.2 31.0 36.7 38.2 50.1 24.5 14.8 15.0 34.6 10.8 14.0 12.3 12.6 19.1 18.5 9.8 11.2 17.2 15.0 39.0 8.6 19.4 20.7 5.5 7.1 7.9 10.2 5.9 6.7 9.3 7.3 8.9 7.5 6.9 10.6 49.7 80.1 57.7 23.2 46.4 120.4 92.4 78.6 113.8 44.1 49.3 35.6 69.1 51.5 81.5 25.8 56.3 43.0 74.6 338.1 25.4 51.0 271.5 130.1 85.5 44.1 62.8 259.8 35.5 52.7 64.6 48.8 93.8 267.2 63.3 40.0 29.6 88.5 41.1 28.6 34.2 119.9 50.8 59.9 51.2 305.8 22.4 85.7 42.7 15.9 80.6 18.3 53.5 34.2 49.5 148.4 210.7 30.1 63.4 118.5 199.5 52.5 72.3 46.4 6.6 43.9 51.6 28.4 10.1 164.2 143.6 88.4 57.3 71.1 77.2 244.4 RIPK3 RIP3 ENSG00000129465 "Receptor interacting serine/threonine kinase 3" Q9Y572 14 24336025-24340022 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.5;Exocrine glandular cells: 35.2;Gastric mucus-secreting cells: 22.4;Paneth cells: 21.4;Proximal enterocytes: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.0;HDLM-2: 4.1;OE19: 10.1;SK-BR-3: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-2)" "unprognostic (1.11e-1)" "unprognostic (5.26e-3)" "unprognostic (9.58e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" 8.6 1.7 0.7 5.6 0.7 4.9 8.0 0.7 1.4 6.4 0.8 15.2 10.2 3.2 1.4 11.9 3.8 5.4 4.1 0.7 0.7 6.2 1.7 8.1 7.7 1.2 0.8 0.7 7.9 0.8 1.2 3.2 1.1 3.4 11.0 0.0 8.9 1.5 1.5 6.5 18.3 2.1 0.8 18.6 10.6 1.1 1.1 3.5 10.7 1.3 7.6 5.4 7.5 1.1 0.0 0.0 0.0 0.0 2.4 2.7 0.0 0.6 3.4 0.0 0.0 0.1 7.0 0.1 1.7 0.3 0.0 1.6 0.0 0.1 0.0 4.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.2 1.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 10.1 0.0 0.0 0.0 1.2 1.2 0.0 0.0 0.0 0.0 11.1 0.0 0.0 1.9 2.9 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.6 0.0 1.7 3.3 4.2 3.7 5.1 3.9 2.1 3.1 3.7 3.3 2.4 1.6 2.3 1.9 2.7 6.0 1.6 6.1 2.9 0.7 0.7 0.7 1.4 0.7 0.7 1.2 0.8 1.1 0.8 1.1 1.1 5.5 3.2 9.1 0.0 5.7 1.5 1.4 5.8 1.8 0.0 2.0 0.9 0.7 2.8 4.7 3.7 0.0 0.3 9.6 38.5 3.9 8.1 0.1 3.2 0.8 4.2 6.1 1.3 0.0 35.2 0.4 1.9 22.4 5.4 12.6 0.0 0.7 0.0 12.7 0.0 0.0 14.4 4.1 9.5 1.6 0.3 0.0 7.7 3.6 1.9 11.6 0.0 10.3 0.0 0.0 17.8 21.4 0.0 5.5 0.5 22.5 0.1 3.7 0.0 0.0 0.2 1.0 0.0 0.3 3.9 1.4 0.3 8.3 0.1 8.0 3.3 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.7;Intestinal goblet cells: 41.6;Undifferentiated cells: 63.6" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 41.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.0;CACO-2: 24.7;Hep G2: 49.4;OE19: 54.7" HPA008079 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.2 10.9 1.7 2.0 3.1 0.7 5.5 9.6 2.7 2.6 1.5 13.4 22.7 1.7 4.4 10.4 4.8 2.7 2.7 2.0 1.3 6.1 9.1 3.6 0.4 1.8 3.4 0.9 8.2 5.2 4.3 4.8 1.9 9.4 19.3 1.2 9.3 4.8 0.3 11.3 16.9 0.6 1.4 0.5 5.8 3.4 2.3 3.7 1.9 0.0 1.5 2.1 5.2 1.4 1.1 17.0 2.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 24.7 8.2 0.0 8.5 0.0 1.9 4.6 0.6 6.8 0.0 8.6 11.3 1.9 0.8 49.4 0.0 0.2 0.1 0.0 13.4 0.0 2.1 0.0 0.0 0.2 0.2 0.4 0.0 0.2 0.1 0.2 0.4 54.7 1.0 0.3 0.0 2.2 5.9 9.0 1.6 0.1 1.6 0.7 0.5 5.4 2.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.4 0.1 0.3 0.0 3.8 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.2 0.0 1.7 3.1 9.6 2.7 2.0 1.3 1.8 3.4 1.9 1.4 2.3 1.4 0.3 3.2 8.9 29.0 2.5 9.6 17.5 14.1 67.7 2.5 17.3 13.6 4.0 17.2 5.8 18.4 2.1 26.0 2.2 33.0 15.6 5.3 1.2 14.6 1.1 1.8 15.5 0.8 1.8 2.7 3.1 0.7 9.7 12.7 0.0 7.2 0.7 11.9 2.6 5.0 1.3 41.6 12.2 0.8 0.9 1.5 0.3 1.3 14.2 4.7 2.8 12.0 10.3 0.0 0.7 6.2 21.1 0.4 1.0 9.9 28.7 2.9 5.6 2.8 0.0 0.5 1.1 1.0 0.8 28.4 6.1 5.9 3.1 0.4 63.6 6.3 RNPEPL1 ENSG00000142327 "Arginyl aminopeptidase like 1" Q9HAU8 2 240565804-240581372 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036772, HPA036773" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA036772: AB_10670848, HPA036773: " "unprognostic (3.92e-2)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.39e-1)" "unprognostic (5.24e-3)" "prognostic favorable (7.43e-4)" "prognostic unfavorable (5.06e-4)" "unprognostic (3.72e-3)" "unprognostic (9.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (5.31e-2)" "unprognostic (9.86e-2)" 40.3 31.4 29.1 14.1 29.6 21.7 32.0 29.0 38.7 15.6 27.0 39.6 20.2 16.8 5.6 52.4 17.0 12.1 79.4 27.9 27.8 42.7 50.6 35.9 23.8 31.5 30.0 12.0 64.2 10.9 9.1 10.6 30.3 34.7 9.5 0.8 28.9 13.1 63.7 35.3 39.8 9.4 31.0 56.4 48.4 9.9 31.4 15.9 19.2 17.1 12.1 34.1 23.2 31.1 13.7 22.4 4.9 13.2 17.6 18.1 16.6 8.6 21.1 9.5 11.6 6.3 39.3 3.9 4.3 21.8 13.3 14.6 5.5 16.1 0.9 23.9 7.7 9.0 7.3 37.2 44.1 5.9 15.5 21.6 25.5 4.9 9.6 15.1 32.8 15.2 6.8 25.7 6.5 19.3 7.5 22.4 6.5 26.5 9.0 15.5 7.4 33.3 39.3 18.5 4.6 9.8 5.8 19.7 39.9 5.6 13.9 26.8 22.7 10.2 10.4 14.4 10.0 24.1 3.9 4.8 20.9 16.6 15.7 9.2 11.2 30.5 14.8 9.9 12.7 8.2 11.3 13.4 8.2 8.7 6.4 9.5 20.0 10.7 10.1 9.5 14.7 7.9 29.1 29.6 29.0 38.7 27.9 27.8 31.5 30.0 30.3 31.0 31.4 31.1 27.9 22.4 25.7 10.4 27.8 7.8 15.0 8.4 2.8 6.4 18.8 9.1 35.6 24.3 12.9 12.9 0.0 7.1 80.4 138.9 17.6 24.6 3.1 12.1 11.0 22.7 26.4 22.3 9.5 49.6 6.8 12.3 104.5 27.4 34.2 31.8 30.0 42.2 43.8 3.3 8.6 58.7 8.2 74.3 21.0 5.9 8.7 47.1 23.2 9.4 52.0 15.9 79.3 5.5 10.3 65.0 70.0 13.5 20.5 20.2 77.1 35.6 7.2 6.9 13.1 14.8 16.4 1.3 8.2 13.0 9.2 5.1 47.9 17.4 60.5 23.0 RRBP1 "ES/130, hES" ENSG00000125844 "Ribosome binding protein 1" Q9P2E9 20 17613678-17682295 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 497.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 588.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.8;plasmacytoid DC: 44.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009026, HPA011924" Enhanced Enhanced "Endoplasmic reticulum" NA NA 320000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA009026: AB_1079852, HPA011924: AB_1856476" "unprognostic (1.56e-3)" "unprognostic (2.26e-3)" "unprognostic (8.46e-2)" "prognostic favorable (1.41e-4)" "unprognostic (1.04e-1)" "unprognostic (1.05e-1)" "unprognostic (2.92e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-2)" "unprognostic (3.03e-1)" "unprognostic (5.09e-2)" "unprognostic (6.63e-2)" "unprognostic (9.21e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.38e-4)" 64.2 72.3 27.0 62.8 41.9 28.1 54.6 41.1 32.2 69.1 52.3 98.3 76.1 59.5 55.0 67.8 45.1 71.5 59.1 27.5 35.3 77.4 219.0 80.2 28.2 49.3 42.2 48.3 497.7 72.4 63.4 107.9 45.5 66.5 65.9 17.7 228.2 63.4 21.9 43.6 82.7 46.0 37.7 57.7 123.1 48.4 40.9 14.4 130.4 14.7 27.0 57.6 55.2 49.2 173.5 121.0 35.7 80.4 160.3 172.2 186.2 264.3 221.3 110.0 148.2 271.2 159.3 66.5 87.3 252.2 113.4 170.4 38.7 215.4 89.1 30.9 29.7 76.2 34.9 283.6 229.4 29.0 93.0 228.9 63.8 178.7 104.3 161.7 109.7 23.4 32.6 62.9 167.6 78.8 11.4 65.5 41.6 383.3 115.8 20.1 94.2 231.3 93.0 58.4 18.2 13.7 151.1 353.2 108.4 75.0 62.0 43.5 198.7 232.7 85.9 122.1 88.5 114.6 93.6 21.6 88.1 30.7 121.1 11.7 8.4 37.8 4.3 5.5 3.2 1.0 1.4 2.6 4.6 1.4 1.4 1.6 7.8 10.7 8.4 44.4 1.5 3.1 27.0 41.9 41.1 32.2 27.5 35.3 49.3 42.2 45.5 37.7 40.9 49.2 146.8 96.1 197.1 15.0 72.5 59.1 92.3 90.3 55.2 21.9 127.0 76.3 46.4 144.4 158.2 95.6 31.3 262.0 180.6 588.9 45.0 199.7 47.2 117.5 228.4 155.8 97.0 31.6 3.0 414.6 235.8 219.7 294.6 322.8 118.9 78.1 118.9 279.9 117.4 25.2 4.9 507.9 50.8 62.0 85.7 44.3 127.1 91.6 71.2 17.8 75.1 144.3 79.3 23.1 27.6 357.7 452.3 83.1 570.6 145.6 221.6 57.2 121.8 35.5 32.9 165.1 169.8 77.5 139.9 73.2 55.8 532.9 56.9 114.6 329.3 218.5 RSAD2 "cig5, vig1, Viperin" ENSG00000134321 "Radical S-adenosyl methionine domain containing 2" Q8WXG1 2 6865557-6898239 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Lyase Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 21.0" "Cell type enhanced" "Detected in many" "Adipocytes: 35.6;Alveolar cells type 1: 35.3;Distal enterocytes: 72.3;Erythroid cells: 44.2;Paneth cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 30.7;eosinophil: 43.3;neutrophil: 25.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 43.3" "Group enriched" "Detected in some" 5 "BJ hTERT+ SV40 Large T+: 75.7;BJ hTERT+ SV40 Large T+ RasG12V: 117.6;HMC-1: 55.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA041160, HPA049409" Approved Supported "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA041160: AB_10795489, HPA049409: AB_2680751" "unprognostic (8.91e-2)" "unprognostic (3.85e-2)" "unprognostic (7.89e-2)" "prognostic unfavorable (4.60e-4)" "unprognostic (3.27e-1)" "unprognostic (3.25e-1)" "unprognostic (1.95e-1)" "unprognostic (2.29e-1)" "unprognostic (3.32e-2)" "unprognostic (3.66e-3)" "unprognostic (9.47e-3)" "unprognostic (4.06e-2)" "unprognostic (1.27e-2)" "unprognostic (3.98e-2)" "unprognostic (4.54e-3)" "unprognostic (4.47e-2)" "unprognostic (1.79e-1)" 4.2 2.3 2.9 4.0 3.7 13.7 3.0 2.1 3.7 6.5 4.6 5.2 3.6 2.1 2.1 1.5 2.8 5.5 5.7 2.7 2.7 2.7 3.5 8.3 2.9 5.1 3.1 2.1 1.5 1.1 3.9 6.6 4.7 1.7 3.0 1.1 21.0 1.9 5.7 0.8 2.9 4.5 11.8 10.1 6.3 2.0 3.0 7.4 1.8 7.6 1.8 2.5 1.4 3.3 0.2 0.0 0.2 0.1 0.0 0.5 0.9 0.0 1.2 75.7 117.6 0.0 2.5 1.1 0.1 0.0 11.6 1.2 0.0 0.0 0.2 0.2 0.0 17.8 0.1 0.0 0.1 0.0 55.7 0.1 0.0 5.7 0.0 0.0 0.0 2.6 1.6 1.0 0.0 0.1 7.0 1.5 0.2 0.0 0.4 0.3 0.0 0.1 0.1 1.1 0.1 0.3 0.1 0.1 3.6 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 1.4 1.5 0.0 0.1 1.2 0.4 30.7 4.9 43.3 2.3 7.5 2.8 0.3 2.6 2.2 2.7 0.4 3.7 3.0 25.2 2.5 7.0 0.3 1.3 2.7 2.9 3.7 2.1 3.7 2.7 2.7 5.1 3.1 4.7 11.8 3.0 3.3 35.6 35.3 3.9 3.9 1.5 0.5 3.3 2.4 1.2 0.8 1.0 0.6 5.2 2.8 3.2 0.0 2.1 0.6 1.9 72.3 0.0 3.8 1.3 19.2 3.1 21.7 9.0 44.2 12.6 6.2 0.8 3.8 34.7 16.1 23.5 8.3 8.9 0.6 9.5 0.0 13.2 2.6 6.1 1.6 2.2 1.1 1.5 8.5 0.0 21.5 7.0 6.3 6.2 17.1 0.9 7.7 107.7 2.2 1.7 4.1 1.7 0.1 13.4 0.7 0.0 2.5 2.8 0.4 0.5 1.2 0.3 2.9 3.6 1.7 1.0 7.4 RTKN B5 ENSG00000114993 Rhotekin Q9BST9 2 74425835-74442422 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 149.6;liver: 124.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 2.3;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 4 "dendritic cells: 6.6;NK-cells: 2.3" "Cell line enhanced" "Detected in many" "Hep G2: 96.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030259 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA030259: AB_10601484" "unprognostic (4.09e-1)" "unprognostic (1.28e-1)" "unprognostic (1.20e-2)" "unprognostic (2.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-3)" "unprognostic (5.32e-2)" "unprognostic (1.95e-2)" "unprognostic (2.57e-2)" "unprognostic (9.43e-3)" "unprognostic (4.99e-2)" "unprognostic (2.48e-2)" "unprognostic (2.96e-2)" "unprognostic (7.15e-2)" "unprognostic (1.85e-1)" "unprognostic (5.81e-2)" "unprognostic (1.23e-3)" 9.8 8.3 69.5 5.0 104.1 0.6 11.3 85.4 84.6 13.5 51.9 20.3 31.8 8.7 3.5 20.8 12.7 14.2 17.3 72.0 84.3 54.4 124.7 10.3 3.1 100.4 95.5 7.7 30.8 20.7 14.7 11.8 95.7 19.1 12.6 1.9 26.0 9.5 12.8 32.0 25.3 6.3 73.4 5.2 15.3 3.3 93.5 6.3 19.5 7.5 5.3 8.3 16.6 149.6 50.4 15.5 19.5 56.3 11.8 13.7 82.1 7.6 9.9 11.0 8.0 76.3 26.8 0.3 21.2 7.4 13.6 67.2 7.3 48.6 5.3 9.9 31.3 12.0 2.8 96.7 7.2 0.0 0.1 8.4 37.7 9.5 30.0 20.2 5.5 0.7 6.2 0.3 16.5 35.8 1.9 10.1 20.9 70.9 30.3 11.1 60.6 7.6 52.4 0.3 19.0 18.8 20.7 79.3 45.2 17.5 44.6 4.4 0.6 20.5 14.0 9.3 10.6 4.8 3.7 1.8 19.6 0.1 19.5 0.0 0.0 0.0 0.2 0.0 0.2 0.7 0.1 0.2 0.6 1.0 0.0 0.1 0.0 2.3 0.0 6.6 0.0 0.4 69.5 104.1 85.4 84.6 72.0 84.3 100.4 95.5 95.7 73.4 93.5 149.6 4.3 9.6 11.8 4.9 2.0 20.0 22.1 37.2 19.4 0.1 14.4 12.2 3.1 28.6 18.3 11.0 2.1 46.7 4.5 21.7 21.5 43.0 0.7 12.6 6.1 8.8 30.7 1.3 0.5 20.1 8.3 8.9 15.8 26.0 1.3 4.9 5.3 40.1 10.1 0.0 0.9 20.1 18.3 2.2 3.8 1.5 12.8 1.1 28.4 3.7 0.7 6.9 5.2 34.7 48.2 30.5 31.0 8.6 1.4 35.4 44.7 54.7 5.8 0.4 6.6 36.9 3.9 1.1 5.6 12.9 21.6 33.4 2.5 3.1 30.5 15.6 RUSC1 NESCA ENSG00000160753 "RUN and SH3 domain containing 1" Q9BVN2 1 155320894-155331114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028510, HPA029922, HPA029923" Approved Enhanced Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA028510: AB_10599847, HPA029922: AB_10611390, HPA029923: AB_10602288" "unprognostic (1.98e-1)" "unprognostic (2.82e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-1)" "unprognostic (5.25e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.78e-6)" "unprognostic (1.42e-1)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (9.24e-6)" "unprognostic (7.59e-2)" "unprognostic (4.25e-2)" "unprognostic (2.05e-2)" "unprognostic (1.40e-1)" 27.0 26.6 42.0 11.6 40.7 12.8 23.2 39.9 66.0 38.0 11.3 39.2 21.6 28.8 8.7 49.5 24.8 16.8 28.8 38.9 41.1 32.1 12.6 23.7 10.7 55.2 34.0 27.5 22.5 11.7 45.0 18.2 53.2 32.1 22.9 11.9 32.0 20.3 14.1 37.3 29.9 18.6 28.3 18.0 27.3 6.6 41.4 18.6 19.3 13.3 11.3 26.6 39.2 41.0 70.4 43.5 24.5 36.4 29.6 32.1 47.2 32.7 20.8 42.2 47.1 50.1 45.2 13.7 24.4 33.2 24.2 95.1 38.3 47.4 18.2 18.8 48.8 19.8 44.7 26.6 24.5 19.9 32.9 33.0 29.3 42.5 14.6 20.4 43.9 29.7 30.5 9.4 36.9 133.4 25.0 25.3 48.4 128.4 68.3 33.6 17.1 24.3 40.3 52.7 25.2 40.5 27.6 76.9 16.8 39.8 114.8 33.6 20.2 54.0 44.4 51.4 65.8 7.4 18.0 8.6 38.2 26.5 15.0 5.8 8.0 4.0 6.3 9.8 7.2 3.6 5.1 6.4 8.8 1.5 2.8 6.0 1.1 3.3 25.2 8.4 5.5 5.4 42.0 40.7 39.9 66.0 38.9 41.1 55.2 34.0 53.2 28.3 41.4 41.0 18.2 9.6 12.7 4.9 8.0 28.0 20.1 29.5 22.8 16.9 21.3 19.3 10.2 15.7 27.9 18.4 6.2 30.8 14.8 82.2 23.5 22.4 0.4 9.9 14.7 20.0 15.6 14.5 23.8 17.7 76.6 19.1 25.5 23.6 8.2 9.8 16.4 7.8 21.0 37.0 30.5 51.7 18.3 12.8 20.3 0.5 18.3 11.9 19.6 6.5 11.7 13.4 15.5 7.1 8.2 25.6 43.7 18.0 8.4 29.4 51.8 27.9 10.4 7.0 19.7 12.7 22.2 2.3 8.9 41.4 34.9 38.0 15.2 6.7 40.1 26.0 SAMD13 ENSG00000203943 "Sterile alpha motif domain containing 13" Q5VXD3 1 84298366-84389957 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;choroid plexus: 26.9;intestine: 22.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 20.3;Intestinal goblet cells: 18.0;Oligodendrocytes: 16.4;Paneth cells: 33.2;Spermatocytes: 22.5;Undifferentiated cells: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "basophil: 12.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 12.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA058929 Enhanced Approved Mitochondria NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA058929: AB_2683855" "unprognostic (3.78e-2)" "unprognostic (4.93e-2)" "unprognostic (8.51e-3)" "unprognostic (7.55e-2)" "prognostic favorable (1.14e-8)" "unprognostic (1.78e-1)" "unprognostic (1.65e-6)" "unprognostic (2.05e-1)" "unprognostic (5.50e-2)" "unprognostic (2.80e-3)" "unprognostic (9.42e-2)" "unprognostic (3.29e-1)" "unprognostic (1.98e-7)" "unprognostic (3.99e-2)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.56e-3)" 0.9 3.4 22.3 1.5 30.7 2.8 2.4 11.3 25.7 1.6 26.9 19.5 3.4 1.7 4.1 0.8 4.1 1.8 2.4 19.6 29.0 1.4 0.4 0.9 1.2 29.0 29.4 0.3 1.8 1.2 1.0 0.8 27.7 4.0 22.0 0.8 17.6 2.1 6.2 1.2 3.8 2.5 29.9 1.1 6.1 13.1 35.5 2.8 9.8 3.0 0.6 1.8 0.4 32.5 0.5 2.3 1.1 3.5 3.6 3.3 2.3 0.3 0.2 0.3 0.2 0.0 3.4 3.6 6.3 0.1 0.7 0.4 0.4 1.2 0.5 2.0 1.7 1.3 1.7 0.3 0.8 4.4 0.0 1.3 1.6 0.1 1.0 2.5 8.2 7.8 0.5 1.1 1.0 1.1 5.1 0.5 3.5 2.9 2.3 0.5 2.5 1.5 6.5 2.1 1.4 5.1 0.1 0.1 8.1 1.4 1.0 4.1 1.4 1.4 0.3 0.3 1.0 2.4 0.5 6.3 0.3 3.8 1.1 12.5 0.3 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.7 0.7 0.3 0.4 0.1 0.5 0.3 0.8 0.0 0.3 22.3 30.7 11.3 25.7 19.6 29.0 29.0 29.4 27.7 29.9 35.5 32.5 1.7 0.0 0.6 2.0 0.3 0.4 0.7 0.7 0.6 1.2 3.8 2.9 1.0 2.8 1.1 1.8 0.0 4.5 0.1 20.3 5.9 2.1 5.6 5.4 1.6 1.6 11.4 6.1 5.2 0.6 0.6 1.4 3.6 4.7 5.7 2.0 3.3 0.1 1.5 0.0 5.8 18.0 0.0 2.4 1.6 5.8 1.8 1.4 8.8 6.5 0.4 2.7 0.0 7.1 16.4 1.1 33.2 2.6 0.1 2.0 3.8 2.9 1.1 0.1 0.0 1.8 0.7 22.5 5.5 2.2 0.3 0.8 0.7 4.1 21.3 1.2 SAMD9 "C7orf5, FLJ20073, KIAA2004" ENSG00000205413 "Sterile alpha motif domain containing 9" Q5K651 7 93099513-93118023 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.1" "Cell type enhanced" "Detected in many" "dendritic cells: 92.7;Distal enterocytes: 104.6;NK-cells: 109.2;Paneth cells: 171.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 28.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 66.7;GAMG: 66.0" "Low region specificity" "Detected in all" "HPA021318, HPA021319" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA021318: AB_2183383, HPA021319: AB_1856554" "unprognostic (3.66e-2)" "unprognostic (5.35e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (8.96e-2)" "unprognostic (1.38e-1)" "unprognostic (7.48e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (4.76e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (8.31e-5)" "unprognostic (6.00e-2)" "prognostic unfavorable (8.40e-7)" "unprognostic (5.91e-2)" "unprognostic (1.37e-2)" "unprognostic (2.18e-2)" "unprognostic (3.64e-1)" 4.1 3.6 1.1 13.2 1.0 9.9 3.5 1.1 1.0 8.0 1.4 11.0 7.5 3.5 2.9 39.1 3.0 7.2 2.4 1.1 1.6 3.2 3.7 7.7 15.8 2.8 1.5 5.8 1.6 1.0 0.9 7.0 2.0 2.0 11.3 0.3 4.3 2.4 0.6 1.9 7.7 4.0 2.9 17.7 10.7 1.0 2.1 20.7 2.0 2.3 15.9 7.0 8.3 2.5 28.5 3.6 1.0 0.2 12.0 15.2 0.3 10.9 45.2 51.0 66.7 0.2 30.9 11.9 16.8 27.1 66.0 32.6 0.1 10.0 17.1 40.5 1.3 17.3 18.0 0.0 5.4 19.5 23.1 6.8 14.1 16.8 4.6 2.8 7.7 13.1 1.2 28.6 10.9 0.1 29.2 15.9 0.1 0.0 7.9 9.5 9.2 13.5 0.3 3.6 4.4 0.4 8.4 3.3 9.1 0.1 1.0 9.5 33.8 11.8 4.2 36.0 6.0 16.9 3.4 10.8 12.3 11.2 12.1 21.8 4.2 15.7 8.3 8.1 7.7 5.6 6.4 7.3 3.6 5.9 6.7 6.1 17.8 8.8 12.8 2.5 8.8 3.2 1.1 1.0 1.1 1.0 1.1 1.6 2.8 1.5 2.0 2.9 2.1 2.5 43.9 9.6 3.7 0.7 53.4 2.3 8.2 40.2 4.0 1.4 4.4 5.1 1.2 5.7 33.7 14.7 0.0 1.9 92.7 104.6 0.0 23.5 0.1 21.1 18.5 29.0 3.0 19.4 0.4 12.3 7.1 14.6 37.8 7.0 43.6 21.8 12.1 1.2 11.5 6.7 1.5 34.9 20.3 29.9 9.6 0.7 15.2 32.7 3.6 21.5 41.6 2.2 109.2 2.0 2.4 50.4 171.0 12.4 35.9 7.0 12.6 2.3 37.5 0.1 13.1 14.4 12.6 0.2 0.0 21.1 1.8 0.4 69.4 25.4 5.6 34.3 SAP30BP "HCNGP, HTRG, HTRP" ENSG00000161526 "SAP30 binding protein" Q9UHR5 17 75667251-75708062 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042382, HPA052943" Supported Enhanced Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA042382: AB_10793881, HPA052943: AB_2681995" "unprognostic (6.92e-2)" "unprognostic (8.56e-3)" "unprognostic (1.20e-1)" "unprognostic (5.34e-3)" "unprognostic (2.95e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.71e-5)" "unprognostic (1.53e-2)" "unprognostic (2.15e-1)" "unprognostic (8.32e-3)" "unprognostic (1.03e-2)" "unprognostic (3.31e-3)" "prognostic unfavorable (1.98e-4)" "unprognostic (1.31e-1)" "unprognostic (1.88e-1)" "unprognostic (6.06e-2)" "unprognostic (6.58e-2)" 17.7 13.1 30.7 14.5 31.9 23.2 17.3 31.1 33.5 20.6 37.9 22.1 11.9 17.0 17.1 20.0 17.0 15.3 19.6 30.8 30.8 20.3 19.0 15.1 19.6 34.6 32.6 17.3 16.2 18.6 17.7 18.0 31.8 19.8 15.1 14.7 23.0 17.1 17.8 17.8 16.0 17.0 31.8 21.1 18.2 14.7 31.6 22.7 15.8 22.2 22.9 19.6 19.0 36.5 28.2 36.9 27.8 26.7 25.6 26.9 31.5 29.2 31.4 53.2 54.8 31.8 23.2 30.2 15.1 27.8 48.8 23.5 33.5 32.0 53.1 10.7 40.1 23.7 26.2 33.2 25.4 25.4 21.5 25.5 28.7 39.9 43.2 30.6 73.5 30.8 29.2 23.0 41.9 29.9 42.0 24.4 23.7 41.7 41.0 27.4 40.4 22.7 44.7 24.7 19.3 31.8 26.4 28.2 33.7 40.7 42.8 22.9 28.7 47.0 30.9 20.9 40.5 17.1 7.1 35.9 31.4 18.8 38.4 18.0 23.1 24.6 24.3 19.8 26.8 21.6 22.0 25.2 19.4 21.7 22.0 22.7 22.8 27.7 23.7 32.0 25.6 22.9 30.7 31.9 31.1 33.5 30.8 30.8 34.6 32.6 31.8 31.8 31.6 36.5 72.4 54.5 62.7 25.5 54.1 49.5 117.7 65.5 34.1 19.6 34.0 43.2 53.5 30.0 71.1 22.0 12.5 59.5 68.3 71.2 68.4 71.3 47.5 32.8 48.4 63.5 35.9 26.9 15.9 73.2 67.0 55.9 45.9 56.3 77.2 38.9 52.8 34.2 57.5 10.1 14.2 43.8 59.0 35.5 48.1 93.6 44.4 48.0 56.9 10.3 59.7 72.6 55.6 22.6 30.5 103.3 109.2 34.6 57.4 52.0 43.3 47.2 58.0 17.3 65.7 50.9 64.3 34.8 34.3 36.1 45.5 96.0 59.8 31.7 37.2 94.0 SCAMP4 FLJ33847 ENSG00000227500 "Secretory carrier membrane protein 4" Q969E2 19 1905372-1926013 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043284 Approved Approved "Golgi apparatus,Vesicles,Lipid droplets,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles" "Lipid droplets, Plasma membrane" "HPA043284: AB_10806501" "unprognostic (1.60e-1)" "unprognostic (3.62e-1)" "unprognostic (5.04e-2)" "prognostic favorable (4.40e-6)" "unprognostic (2.58e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.92e-5)" "unprognostic (2.04e-1)" "unprognostic (1.58e-1)" "unprognostic (2.55e-1)" "unprognostic (3.01e-3)" "unprognostic (5.66e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.16e-2)" "unprognostic (1.58e-1)" "unprognostic (3.93e-2)" "unprognostic (1.03e-1)" 23.2 27.4 31.1 15.5 39.9 11.4 25.4 41.3 33.3 28.1 33.6 23.3 19.8 26.0 17.5 39.9 38.3 19.5 15.5 28.9 33.1 34.4 28.3 25.5 15.6 51.5 42.9 27.1 36.5 15.8 31.8 18.8 47.7 31.7 9.8 7.4 43.9 20.4 13.9 36.3 20.3 12.3 39.7 25.1 26.4 22.0 40.6 8.3 32.7 5.8 9.4 22.0 25.0 53.5 53.6 53.9 25.7 56.8 50.7 31.7 29.6 35.5 33.1 39.3 46.7 44.9 51.1 22.5 32.1 30.7 23.1 63.7 24.7 38.2 14.5 34.8 21.7 15.8 19.0 44.3 65.6 16.9 23.2 48.8 24.2 34.8 21.2 32.9 27.2 25.2 35.7 25.3 23.3 67.8 21.5 31.6 38.8 31.1 18.6 25.9 18.1 34.6 49.8 47.5 33.8 45.0 23.9 49.9 31.4 18.1 50.6 41.5 29.6 44.8 30.5 81.1 35.7 57.8 62.6 21.0 59.1 26.9 30.1 1.7 4.4 1.9 3.9 4.9 2.0 5.1 2.7 2.6 4.8 3.4 1.5 2.9 2.1 5.8 4.5 12.0 2.3 3.7 31.1 39.9 41.3 33.3 28.9 33.1 51.5 42.9 47.7 39.7 40.6 53.5 16.9 9.6 7.3 12.1 22.9 17.1 25.0 20.8 33.0 19.7 40.0 23.5 3.0 21.5 14.1 49.7 75.0 40.0 59.6 53.0 7.9 20.8 0.8 63.2 23.2 17.8 18.7 11.6 8.3 12.5 38.1 18.2 43.3 42.1 17.2 27.8 15.7 13.4 38.0 21.9 8.0 36.1 20.3 20.1 24.9 1.9 21.8 24.2 21.4 5.6 21.0 29.6 33.0 16.6 18.9 16.1 25.3 17.3 16.0 30.0 47.6 10.1 33.2 52.2 0.0 15.8 15.7 19.0 26.1 30.8 20.2 59.0 20.4 26.9 31.1 28.1 SCAND1 "RAZ1, SDP1" ENSG00000171222 "SCAN domain containing 1" P57086 20 35953617-35959472 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 241.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071335 Approved "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA071335: " "unprognostic (3.88e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-1)" "unprognostic (1.21e-2)" "unprognostic (4.09e-3)" "unprognostic (2.67e-2)" "unprognostic (1.56e-2)" "unprognostic (7.15e-3)" "unprognostic (3.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.48e-2)" 67.4 92.4 25.8 20.2 24.5 44.3 66.2 30.2 51.7 54.9 34.4 61.5 35.4 62.4 4.7 63.1 58.1 5.3 72.6 27.5 31.9 96.0 117.9 51.7 13.8 39.8 29.6 61.1 76.8 9.7 69.6 9.5 28.7 83.7 3.9 2.7 61.0 11.1 85.0 69.4 61.8 5.5 26.8 78.5 66.4 56.7 28.2 10.3 65.7 6.3 4.9 55.5 49.5 26.4 57.0 41.6 14.6 30.1 8.0 9.0 102.2 38.1 14.5 16.0 18.3 37.2 41.0 44.2 96.8 5.7 20.4 52.3 3.3 17.3 1.8 15.8 93.3 105.9 23.5 86.2 28.1 33.7 41.8 16.9 14.3 13.0 2.9 8.9 26.3 42.9 47.7 34.4 9.9 58.6 95.5 241.1 52.9 20.3 162.5 70.8 48.6 73.6 16.4 22.7 78.8 114.4 63.7 100.4 89.2 2.0 67.8 62.7 52.2 54.5 49.7 53.3 37.5 99.6 55.0 64.2 63.8 35.7 42.3 401.5 267.5 274.6 149.3 191.8 120.8 172.0 149.7 134.2 208.6 192.2 124.2 120.8 241.8 149.4 196.2 278.5 224.0 213.7 25.8 24.5 30.2 51.7 27.5 31.9 39.8 29.6 28.7 26.8 28.2 26.4 114.4 32.1 61.9 11.1 115.7 60.0 164.0 188.6 96.2 67.6 118.8 112.0 43.1 133.0 126.9 165.5 43.8 158.3 123.3 410.8 311.0 241.4 336.3 159.6 98.0 123.0 281.3 131.1 5.5 337.3 159.7 105.6 159.0 127.2 69.7 122.4 185.6 292.4 205.9 52.2 7.1 269.8 201.4 197.4 91.5 79.8 118.7 134.5 104.9 6.5 202.2 154.6 148.3 7.1 14.3 283.0 418.6 100.1 137.2 162.4 378.8 596.9 149.1 88.0 111.7 83.9 117.4 96.0 38.2 110.3 75.0 163.8 131.0 153.8 200.8 217.3 SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.8;intestine: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.3;Club cells: 64.8;Collecting duct cells: 57.0;Distal enterocytes: 262.8;Ionocytes: 107.8;Paneth cells: 73.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 26.4" "Region enriched" "Detected in single" 9 "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 33.3;RPMI-8226: 9.2;RT4: 18.5;U-266/70: 55.4;U-266/84: 20.2" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA015612: AB_1856629" "unprognostic (7.45e-2)" "unprognostic (1.76e-3)" "unprognostic (1.39e-1)" "unprognostic (6.74e-3)" "unprognostic (1.74e-2)" "unprognostic (5.11e-3)" "unprognostic (7.74e-2)" "unprognostic (5.49e-3)" "unprognostic (2.60e-1)" "unprognostic (2.40e-1)" "unprognostic (3.68e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.32e-1)" "unprognostic (4.66e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" 18.5 0.4 0.0 1.1 0.0 0.2 17.7 1.0 0.0 48.5 0.0 94.2 2.5 2.8 0.1 82.8 3.7 0.5 0.3 0.0 0.0 31.7 0.2 23.9 0.8 0.0 0.0 0.7 2.1 0.3 1.0 3.6 0.1 10.5 35.6 0.0 39.5 2.4 1.4 36.0 4.3 0.8 0.0 3.7 24.1 0.3 0.0 0.7 9.2 0.8 5.4 8.3 56.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 7.0 0.0 0.0 9.2 0.0 18.5 0.2 0.0 0.0 0.5 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 55.4 20.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 25.7 99.3 28.3 0.0 7.1 3.1 15.4 27.8 5.7 0.0 4.4 3.0 0.7 0.0 64.8 57.0 0.0 0.7 0.1 262.8 0.0 0.0 0.1 11.9 1.6 6.2 7.7 0.0 0.3 0.4 0.3 1.0 36.7 23.4 8.2 0.0 1.1 0.1 0.1 0.0 0.3 21.4 107.8 0.0 0.0 0.2 0.0 1.0 10.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 73.7 0.0 38.7 6.1 0.0 0.1 9.2 0.0 0.0 0.1 0.7 0.1 0.4 29.8 5.4 2.2 1.4 0.0 15.2 19.7 SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 112.2;Paneth cells: 131.5;Proximal enterocytes: 110.7;Suprabasal keratinocytes: 98.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA046943: AB_2732536, HPA056254: AB_2683080" 16.8 10.3 14.0 13.4 13.8 36.5 7.8 14.4 16.8 6.8 18.2 22.0 25.6 3.6 4.7 12.3 15.8 7.7 10.3 14.3 14.4 8.1 18.4 14.4 9.1 18.8 19.1 1.8 11.5 7.2 1.5 8.3 17.5 5.1 10.5 0.1 21.3 6.7 10.2 11.0 19.7 12.7 16.4 11.4 10.2 4.1 17.4 11.2 2.3 10.1 10.3 13.0 2.5 17.4 37.4 29.9 1.3 12.5 17.7 24.2 18.7 19.5 24.1 38.0 32.8 35.3 17.8 42.7 19.7 22.6 9.6 36.0 19.3 31.5 6.1 7.6 82.5 13.8 20.2 46.7 44.6 43.8 18.3 38.4 48.6 19.4 15.8 10.6 24.4 5.8 15.6 32.9 16.8 55.7 13.3 76.5 11.0 15.5 54.8 26.1 7.5 65.0 29.6 21.3 16.6 23.7 24.4 70.7 63.5 1.3 26.1 24.7 25.8 16.3 22.6 30.2 22.2 26.1 15.6 29.2 35.7 28.7 14.5 19.1 21.8 12.2 43.9 19.9 42.2 40.1 38.9 44.1 34.9 33.4 29.2 32.6 21.6 27.7 21.1 56.2 37.0 37.7 14.0 13.8 14.4 16.8 14.3 14.4 18.8 19.1 17.5 16.4 17.4 17.4 0.0 3.2 2.7 2.9 20.0 85.7 21.6 75.5 44.3 7.3 0.1 0.0 16.8 21.5 31.4 0.0 2.1 0.0 5.3 112.2 0.0 0.0 15.1 0.1 0.2 13.8 25.8 14.1 2.7 0.0 0.0 14.1 24.5 0.1 15.9 0.0 18.2 53.5 0.0 11.8 2.7 63.2 48.8 28.2 63.6 25.6 16.4 29.2 42.7 5.6 47.3 5.5 25.7 5.5 1.4 0.1 131.5 10.9 32.1 40.0 110.7 0.1 42.6 7.1 0.0 30.4 29.5 17.3 35.7 56.1 98.9 0.0 14.9 0.1 90.7 22.3 SCRIB "KIAA0147, SCRB1, Vartul" ENSG00000180900 "Scribble planar cell polarity protein" Q14160 8 143790920-143815773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host interferon signaling pathway by virus, Inhibition of host STAT1 by virus, Inhibition of host STAT2 by virus, Viral immunoevasion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015463, CAB022081, HPA023557, HPA064312" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions,Rods & Rings" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Nucleoplasm, Rods & Rings" "CAB015463: AB_2238926, CAB022081: , HPA023557: AB_2671238, HPA064312: AB_2685242" "unprognostic (1.24e-1)" "unprognostic (1.94e-2)" "unprognostic (7.78e-2)" "unprognostic (8.95e-2)" "unprognostic (3.77e-1)" "unprognostic (3.96e-2)" "unprognostic (1.14e-3)" "unprognostic (1.86e-2)" "unprognostic (2.46e-1)" "unprognostic (2.56e-1)" "unprognostic (8.22e-2)" "unprognostic (1.87e-1)" "unprognostic (2.16e-3)" "unprognostic (3.46e-3)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" 18.7 17.1 11.5 7.2 10.8 5.6 23.6 6.0 10.4 45.6 0.0 32.3 9.1 24.7 0.9 100.5 26.0 3.4 24.6 8.7 2.7 27.7 25.4 21.3 4.0 10.7 8.1 23.0 38.8 5.2 24.8 5.0 5.9 28.4 3.4 1.0 40.2 5.2 54.3 68.3 26.5 2.0 4.9 22.9 30.0 26.4 9.0 3.0 24.6 1.7 3.9 27.8 52.6 15.3 55.7 33.1 12.7 20.5 5.1 6.9 33.0 30.9 5.3 11.2 9.1 15.3 29.8 24.2 39.7 7.2 4.6 52.4 7.9 32.9 1.7 30.8 58.5 24.6 30.5 26.1 10.8 13.0 14.8 5.1 29.9 9.4 5.5 5.1 11.5 19.8 42.2 6.4 7.5 93.0 38.1 26.9 15.7 25.0 55.1 44.5 10.6 25.0 5.6 45.5 29.6 27.1 31.4 30.5 33.6 4.5 41.5 28.2 25.7 10.1 64.1 25.2 44.7 31.6 31.0 23.8 13.1 9.5 19.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.5 10.8 6.0 10.4 8.7 2.7 10.7 8.1 5.9 4.9 9.0 15.3 12.3 0.0 9.9 33.0 4.4 8.5 5.0 10.2 13.6 11.3 16.8 17.0 11.1 11.5 8.3 14.7 14.6 11.0 9.7 28.7 3.9 8.6 1.5 14.0 7.7 7.8 13.8 13.7 5.0 9.4 6.3 7.3 29.6 27.3 0.0 17.9 3.6 8.8 6.5 5.0 6.2 17.8 18.3 6.0 4.1 0.7 9.0 6.6 8.8 6.5 5.0 10.0 5.2 12.1 15.2 11.5 22.8 9.8 5.6 9.3 16.9 4.5 9.9 16.0 13.1 12.0 8.7 9.4 10.0 19.9 10.7 5.1 7.3 8.0 23.2 7.1 SEC23A ENSG00000100934 "Sec23 homolog A, COPII coat complex component" Q15436 14 39031919-39109646 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 347.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043806, HPA069974" Uncertain Approved Nucleoplasm,Vesicles NA NA 83000 "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA043806: , HPA069974: AB_2686223" "unprognostic (2.40e-1)" "prognostic unfavorable (5.75e-4)" "prognostic favorable (3.56e-4)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (5.85e-2)" "unprognostic (1.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.69e-4)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.16e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-3)" 45.9 32.0 11.4 31.8 14.2 13.1 20.9 18.3 16.8 36.2 31.4 40.0 57.7 42.7 19.9 34.1 21.5 32.1 46.9 13.3 18.9 23.1 80.8 20.2 21.0 13.8 14.0 33.9 12.0 8.1 10.5 27.1 15.3 34.0 34.2 38.5 10.5 52.6 54.2 12.8 52.6 90.5 7.6 20.5 16.8 23.5 12.7 18.9 17.9 58.5 22.0 40.7 17.9 15.4 52.1 90.8 76.9 74.7 161.3 173.0 25.9 195.1 176.4 135.2 166.8 93.2 44.2 12.6 46.9 279.6 54.9 41.2 99.6 86.3 208.6 39.6 36.9 21.8 67.7 347.3 122.4 35.9 31.3 134.0 48.8 91.6 73.7 114.6 130.8 26.9 15.6 30.1 125.8 47.5 32.9 16.9 18.4 81.7 91.3 44.0 111.8 19.1 84.7 75.6 8.5 20.5 132.8 43.0 51.8 68.6 51.5 12.4 138.4 75.0 57.8 110.8 52.0 27.0 36.6 56.0 50.3 31.4 70.2 70.5 34.3 38.6 26.6 29.3 38.4 23.6 33.1 34.9 31.1 21.1 34.9 28.0 29.5 42.1 27.3 26.7 38.1 31.4 11.4 14.2 18.3 16.8 13.3 18.9 13.8 14.0 15.3 7.6 12.7 15.4 35.4 16.0 26.9 34.9 30.5 25.9 33.5 15.5 15.4 39.7 11.8 10.3 54.6 15.7 18.8 31.3 68.8 16.0 36.0 87.0 7.9 9.8 13.4 11.3 42.8 41.1 24.5 6.1 48.3 5.6 43.7 55.0 26.5 18.8 27.9 56.9 118.9 133.6 25.6 30.3 51.1 31.6 12.2 36.4 32.3 18.6 74.9 24.3 24.9 48.7 25.6 19.4 32.0 34.2 44.3 17.8 34.1 71.5 38.5 37.5 88.6 32.8 10.1 58.7 39.5 27.6 51.4 18.0 15.5 15.7 24.0 24.8 32.3 31.0 30.2 56.5 SEC61A1 ENSG00000058262 "SEC61 translocon subunit alpha 1" P61619 3 128051641-128071683 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022076 Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "CAB022076: " "unprognostic (1.84e-1)" "unprognostic (8.00e-2)" "unprognostic (8.21e-2)" "prognostic favorable (7.82e-4)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (2.84e-2)" "unprognostic (4.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.84e-9)" "unprognostic (2.73e-2)" "unprognostic (3.18e-2)" "unprognostic (8.33e-2)" "unprognostic (2.51e-2)" 82.1 100.7 31.3 88.3 33.4 79.5 75.3 33.5 34.7 144.5 52.4 90.7 81.9 88.9 128.9 88.7 78.1 81.7 74.2 32.3 39.6 64.6 134.8 93.3 60.2 40.9 37.6 67.3 272.1 111.7 93.5 112.8 36.0 90.0 90.0 37.0 176.3 97.0 70.5 66.9 75.8 110.7 36.6 73.7 105.5 38.8 46.6 61.4 104.8 59.3 80.6 97.0 68.7 35.8 272.8 136.5 132.0 240.3 367.9 317.3 256.9 426.9 470.8 349.0 371.2 259.1 186.9 184.7 259.5 534.8 266.2 232.6 209.0 291.3 334.2 168.1 126.2 213.5 143.5 273.6 542.9 264.1 225.9 348.1 345.4 329.3 422.4 265.0 314.3 122.2 136.9 415.3 412.8 237.7 135.1 87.5 184.6 231.6 202.8 144.2 125.5 349.8 181.4 229.3 155.8 162.4 216.0 193.5 270.7 152.0 184.2 215.1 327.3 278.3 164.7 333.7 201.4 386.6 210.6 265.8 456.3 166.2 369.1 160.3 88.6 67.0 89.0 79.6 120.0 43.8 62.9 78.2 82.6 26.1 38.8 46.2 22.5 65.0 84.2 114.0 45.1 116.9 31.3 33.4 33.5 34.7 32.3 39.6 40.9 37.6 36.0 36.6 46.6 35.8 31.9 32.1 33.1 18.6 46.6 37.0 25.7 44.4 30.7 17.0 63.5 41.3 15.0 37.1 43.3 49.7 35.5 64.3 59.2 107.2 3.9 81.0 42.2 28.2 72.9 45.9 73.6 19.5 12.6 154.5 136.3 57.4 77.5 68.6 26.0 55.6 49.6 118.2 75.9 26.9 18.5 150.8 38.7 34.8 32.1 25.7 41.0 38.2 33.8 26.2 32.1 22.4 28.8 19.1 17.2 104.9 50.2 43.6 192.8 69.6 63.5 26.8 31.0 15.5 32.9 25.6 47.2 12.3 18.4 42.5 29.5 127.9 32.4 52.6 100.4 44.6 SECTM1 K12 ENSG00000141574 "Secreted and transmembrane 1" Q8WVN6 17 82321024-82334074 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 90.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.4;Kupffer cells: 52.7;Macrophages: 36.8;Paneth cells: 48.2;Proximal enterocytes: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 154.2" "Group enriched" "Detected in many" 13 "granulocytes: 154.2;monocytes: 58.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 83.3;BJ hTERT+: 86.7;BJ hTERT+ SV40 Large T+: 66.1;BJ hTERT+ SV40 Large T+ RasG12V: 64.4;PC-3: 70.2;SiHa: 122.5;SK-BR-3: 66.9;U-2197: 92.8" "Low region specificity" "Detected in some" HPA051214 Approved "Secreted to blood" NA NA 16000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA051214: AB_2732565" "unprognostic (2.42e-1)" "unprognostic (2.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.15e-2)" "unprognostic (4.55e-2)" "unprognostic (9.39e-2)" "unprognostic (3.17e-3)" "unprognostic (7.75e-3)" "unprognostic (2.10e-2)" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.43e-1)" "unprognostic (4.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" 20.7 4.0 1.4 40.5 1.3 11.7 13.0 1.1 2.9 15.0 2.4 36.7 66.8 11.0 1.7 12.8 14.3 12.4 5.9 1.3 2.0 35.9 5.9 28.7 17.4 3.4 1.9 5.8 4.1 1.9 2.4 13.1 2.7 13.9 23.6 0.1 34.6 5.7 2.4 15.9 90.4 14.6 1.8 42.4 24.4 1.6 2.1 5.8 3.8 2.5 8.5 17.8 13.4 1.9 20.4 4.5 0.0 1.4 33.3 83.3 1.7 9.9 86.7 66.1 64.4 2.1 40.9 0.0 0.4 29.1 1.0 60.4 0.0 4.0 2.5 6.5 0.2 8.3 28.2 5.5 25.4 0.0 0.0 35.8 8.6 3.6 1.5 4.9 1.9 0.2 0.3 0.1 42.7 0.8 0.1 0.1 0.2 5.3 70.2 0.0 0.5 1.0 19.0 0.1 4.5 0.5 122.5 66.9 1.5 0.2 5.6 1.8 0.7 7.5 0.6 92.8 0.1 0.3 0.0 0.1 1.7 0.0 0.4 0.1 30.9 0.0 0.4 58.2 0.3 0.0 0.6 0.2 8.3 0.0 0.1 0.1 154.2 0.0 56.3 3.5 0.0 4.5 1.4 1.3 1.1 2.9 1.3 2.0 3.4 1.9 2.7 1.8 2.1 1.9 8.2 12.8 2.4 0.0 1.0 9.4 4.6 0.8 5.2 0.0 4.4 1.5 0.9 0.0 3.0 1.8 0.0 0.3 1.8 63.4 0.0 9.5 0.1 3.0 4.4 6.0 0.0 0.0 0.0 9.9 0.9 6.1 8.6 7.3 1.3 0.0 3.6 1.3 7.1 0.0 0.0 8.7 2.0 52.7 10.7 0.4 5.3 36.8 1.8 0.0 19.5 0.0 1.0 0.0 0.0 5.4 48.2 0.0 1.1 19.5 62.5 3.2 3.6 0.0 0.0 0.6 1.8 0.1 0.2 0.9 3.4 0.3 1.1 0.0 1.3 21.3 SELENBP1 "hSBP, hSP56, LPSB" ENSG00000143416 "Selenium binding protein 1" Q13228 1 151364304-151372707 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 509.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 525.6;Distal enterocytes: 1056.9;Erythroid cells: 590.9;Hepatocytes: 501.5;Paneth cells: 451.4;Undifferentiated cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.4" "Lineage enhanced" "Detected in single" "dendritic cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 144.9;HEL: 120.5;HSkMC: 75.9;OE19: 92.8;SK-BR-3: 274.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005741, CAB008366, HPA011731" Enhanced Supported Nucleoli NA NA 59000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "CAB008366: AB_592677, HPA005741: AB_1856662, HPA011731: AB_1856663" "unprognostic (1.51e-1)" "unprognostic (7.01e-2)" "unprognostic (8.52e-3)" "unprognostic (6.25e-3)" "unprognostic (6.28e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.08e-2)" "unprognostic (1.21e-2)" "unprognostic (3.78e-3)" "unprognostic (2.86e-1)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (2.67e-2)" "unprognostic (6.98e-2)" "unprognostic (1.95e-1)" "unprognostic (1.86e-2)" "unprognostic (6.86e-3)" 128.3 18.7 49.8 24.9 53.0 95.9 76.3 45.5 54.8 57.0 47.4 509.3 74.7 31.3 43.4 31.8 132.7 52.2 69.1 47.1 48.2 77.2 261.7 181.0 10.9 47.8 51.0 49.4 29.0 11.9 15.0 20.4 46.5 44.2 471.7 3.9 61.6 48.8 72.9 25.2 94.2 49.5 46.9 51.1 126.4 6.1 51.0 7.1 115.1 138.1 6.8 58.3 29.3 45.7 0.0 17.2 31.9 1.8 144.9 59.1 8.4 5.9 2.6 3.1 6.5 18.1 5.4 0.0 30.7 10.7 0.0 0.4 0.0 0.4 2.8 0.1 14.8 120.5 53.1 28.9 30.5 0.2 0.0 75.9 1.0 5.3 0.1 0.4 19.0 0.0 12.4 0.0 8.0 13.2 0.0 0.0 26.6 92.8 32.2 0.1 1.7 0.7 7.1 0.0 0.4 0.7 0.5 274.4 0.0 25.1 49.4 1.8 1.8 0.0 1.1 16.8 0.1 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 49.8 53.0 45.5 54.8 47.1 48.2 47.8 51.0 46.5 46.9 51.0 45.7 36.6 294.9 525.6 38.2 4.0 10.8 27.7 56.4 30.7 0.3 73.0 59.9 135.7 75.8 123.9 5.5 0.0 2.4 1.9 1056.9 115.4 17.1 0.7 30.9 14.9 27.5 155.0 590.9 0.1 9.1 2.1 85.2 163.6 14.1 27.3 10.9 26.0 501.5 15.3 0.0 0.1 137.2 79.3 39.6 12.4 4.2 66.5 3.9 33.8 13.1 0.2 37.4 0.0 0.0 2.0 6.5 451.4 80.9 0.8 25.6 251.0 148.3 101.5 1.4 52.6 15.6 102.3 0.1 0.3 22.7 9.9 4.0 5.7 30.5 452.4 71.0 SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969518-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.6;liver: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.4;Gastric mucus-secreting cells: 27.0;Hepatocytes: 60.5;Intestinal goblet cells: 34.6;Paneth cells: 38.5;Proximal enterocytes: 47.6;Undifferentiated cells: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 31.7;CACO-2: 30.5;Hep G2: 113.8;OE19: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" NA NA 1300000 "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" 2.4 12.7 13.1 5.9 10.9 0.4 3.6 18.9 12.3 6.9 12.8 53.6 53.4 3.5 32.1 3.6 5.9 9.0 3.0 10.0 11.6 19.1 102.4 5.8 2.5 11.2 14.4 18.9 31.3 7.3 9.9 3.9 11.5 20.2 84.6 7.3 8.5 3.0 2.6 18.3 41.2 4.6 9.6 3.1 20.9 3.7 17.0 0.8 15.3 0.8 0.9 4.0 5.0 9.9 0.2 31.7 8.0 3.4 5.0 1.6 6.8 1.2 3.4 1.7 1.7 30.5 5.2 0.5 4.2 1.5 0.6 2.1 8.0 1.4 1.4 0.7 4.9 1.7 3.0 113.8 12.5 1.2 1.0 8.3 1.8 1.6 0.9 22.2 4.4 3.5 3.3 0.4 2.5 2.0 0.5 1.2 1.3 69.1 1.8 3.1 0.7 1.5 7.4 1.0 2.5 12.5 1.1 2.1 3.2 8.7 8.7 1.5 3.0 1.0 3.7 0.8 0.3 1.1 0.6 0.5 0.9 1.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 10.9 18.9 12.3 10.0 11.6 11.2 14.4 11.5 9.6 17.0 9.9 0.3 3.2 1.1 3.9 1.2 0.0 0.6 0.7 0.6 3.5 2.5 2.0 1.2 20.0 0.2 0.0 0.0 8.8 0.0 66.4 0.0 2.7 0.2 1.6 0.7 0.6 8.5 0.8 3.0 2.6 1.9 2.0 27.0 0.3 0.0 3.4 2.2 60.5 0.9 11.8 14.1 34.6 2.0 3.3 0.0 0.2 2.1 0.2 1.8 0.0 0.0 0.9 0.0 3.5 5.5 2.4 38.5 1.2 0.2 3.0 47.6 6.4 2.4 1.6 0.0 0.1 0.4 1.1 1.9 0.5 0.1 2.9 0.2 12.7 45.9 0.9 SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 235.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.3;Distal enterocytes: 530.1;Ductal cells: 735.4;Pancreatic endocrine cells: 457.4;Paneth cells: 465.1;Proximal enterocytes: 422.0;Syncytiotrophoblasts: 446.6;Urothelial cells: 432.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 305.6;HaCaT: 349.2;HBEC3-KT: 553.0;hTCEpi: 307.8;RT4: 381.9;SK-BR-3: 311.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA005974: AB_10603239" "unprognostic (1.41e-1)" "unprognostic (3.70e-3)" "unprognostic (8.78e-3)" "prognostic favorable (1.69e-7)" "unprognostic (6.78e-2)" "unprognostic (5.31e-2)" "prognostic unfavorable (2.11e-4)" "prognostic unfavorable (5.70e-4)" "unprognostic (3.12e-2)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (4.63e-3)" "unprognostic (2.67e-2)" 6.5 23.8 1.2 15.0 1.4 8.1 33.8 1.5 1.2 68.9 2.9 111.0 118.7 15.3 21.4 120.7 18.9 59.1 3.2 1.0 1.7 114.1 235.5 20.9 3.5 1.8 2.2 0.9 37.7 45.8 9.7 44.5 1.9 56.6 56.2 0.1 151.0 62.1 76.8 53.5 105.6 2.6 1.6 3.4 90.7 4.9 5.8 8.8 28.4 24.5 9.5 116.5 39.3 1.8 87.3 20.5 17.7 57.0 37.3 50.4 48.2 162.8 119.5 10.6 13.1 31.1 305.6 57.0 209.5 154.6 12.9 349.2 2.3 553.0 2.1 5.5 13.2 0.0 17.2 16.6 42.0 0.5 64.1 46.0 307.8 66.5 144.2 45.5 6.7 6.9 2.6 0.5 18.2 14.2 2.1 2.0 18.3 172.1 42.4 0.4 34.8 19.5 57.9 381.9 7.6 42.4 41.7 311.0 6.5 8.5 182.8 9.9 40.7 2.8 13.0 1.8 3.4 2.9 2.1 2.6 1.4 1.6 13.7 0.0 2.4 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 10.4 0.0 0.6 1.2 1.4 1.5 1.2 1.0 1.7 1.8 2.2 1.9 1.6 5.8 1.8 2.2 16.0 8.9 0.0 2.7 12.4 108.7 374.7 37.0 0.0 162.9 72.9 0.7 138.7 173.3 117.7 0.0 466.3 4.2 530.1 72.4 735.4 6.4 61.6 18.2 8.8 116.6 3.6 0.4 326.3 91.2 5.4 80.0 140.7 0.0 1.6 5.7 54.5 47.5 0.0 0.4 195.0 183.1 5.1 5.0 12.9 2.1 13.1 40.9 1.0 48.4 0.6 0.0 0.0 0.2 457.4 465.1 0.0 0.1 192.2 422.0 71.0 54.3 0.0 0.0 23.5 19.3 0.7 9.5 30.8 21.2 446.6 3.5 0.1 145.7 432.5 SGK2 ENSG00000101049 "Serum/glucocorticoid regulated kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.5;kidney: 53.6;liver: 63.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.5;Distal tubular cells: 76.3;Hepatocytes: 32.8;Paneth cells: 21.7;Proximal enterocytes: 23.8;Proximal tubular cells: 25.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 20.5;CAPAN-2: 14.2;Hep G2: 18.7;OE19: 61.7;RPTEC TERT1: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA008859: AB_2668159, HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favorable (5.65e-4)" 23.5 1.4 4.9 1.5 14.8 0.5 6.1 12.6 10.5 3.5 0.7 37.7 31.6 1.8 33.8 1.0 3.7 10.0 1.2 6.0 7.7 53.6 63.2 1.0 0.2 18.1 13.3 6.6 16.2 0.5 3.0 0.8 14.3 2.6 40.5 5.6 1.8 2.9 0.4 6.2 20.1 1.6 11.8 1.1 22.8 1.8 13.3 0.3 1.7 0.4 0.3 4.2 3.0 24.5 0.0 20.5 0.3 0.1 0.3 0.0 0.1 0.2 0.0 0.2 0.0 0.6 14.2 0.1 8.7 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.4 0.0 18.7 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.1 0.1 0.5 0.1 61.7 0.0 0.1 0.1 0.0 25.4 4.2 0.2 1.0 0.0 1.2 0.1 0.4 0.0 0.1 0.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 14.8 12.6 10.5 6.0 7.7 18.1 13.3 14.3 11.8 13.3 24.5 0.3 0.0 0.0 4.9 0.2 0.1 0.1 0.2 0.0 0.8 0.3 0.8 4.9 8.6 0.0 11.0 0.0 5.1 0.0 76.5 76.3 6.8 0.3 0.9 0.5 0.6 1.8 0.0 0.7 6.3 1.3 0.4 11.2 2.4 0.0 0.7 0.7 32.8 0.7 6.7 1.3 4.1 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 3.5 20.7 2.5 21.7 0.4 0.0 0.1 23.8 25.5 0.2 0.8 0.0 0.2 0.4 0.1 0.1 0.0 0.1 17.1 0.2 0.0 7.7 0.3 SGTA SGT ENSG00000104969 "Small glutamine rich tetratricopeptide repeat containing alpha" O43765 19 2754715-2783362 "Predicted intracellular proteins" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056309 Approved Approved Nucleoplasm NA NA 81000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA056309: AB_2683096" "unprognostic (2.31e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.13e-1)" "prognostic favorable (1.04e-4)" "unprognostic (7.99e-2)" "unprognostic (1.06e-1)" "unprognostic (2.52e-3)" "unprognostic (1.47e-1)" "unprognostic (7.23e-2)" "unprognostic (1.97e-1)" "unprognostic (7.58e-3)" "unprognostic (2.89e-2)" "prognostic favorable (2.35e-4)" "unprognostic (1.87e-2)" "unprognostic (1.23e-1)" "unprognostic (4.04e-1)" "unprognostic (3.04e-1)" 38.4 46.4 60.2 16.8 61.7 29.0 39.8 61.4 76.0 40.8 45.4 53.4 27.3 44.2 18.6 53.3 42.0 13.8 91.0 60.1 57.6 54.7 72.3 37.5 19.9 64.9 62.9 52.8 57.8 22.1 56.5 22.0 60.4 51.1 9.3 17.2 36.2 18.6 110.8 40.2 37.6 14.9 61.7 49.2 47.7 54.1 61.3 31.6 47.9 43.4 13.2 43.7 38.1 66.5 67.9 58.8 57.4 56.5 21.7 23.9 45.9 46.8 35.7 71.3 60.8 95.4 31.4 61.5 37.7 39.4 44.4 53.3 70.2 79.5 24.6 0.0 59.3 37.8 25.0 81.8 56.0 49.0 46.5 39.1 39.2 58.5 45.6 27.5 51.5 60.5 95.6 57.6 38.3 46.4 87.8 70.8 98.2 51.6 57.3 113.8 43.7 80.8 48.0 43.0 104.2 85.6 31.6 61.0 73.4 21.5 66.8 76.0 41.0 50.7 53.2 91.3 86.8 101.1 88.1 82.6 65.6 122.2 81.1 17.3 21.4 20.9 17.4 28.1 20.4 15.4 19.0 19.1 23.6 13.9 14.4 14.4 20.7 21.2 27.8 20.5 25.4 21.8 60.2 61.7 61.4 76.0 60.1 57.6 64.9 62.9 60.4 61.7 61.3 66.5 31.6 9.6 15.7 15.3 26.3 23.7 24.0 21.2 17.1 42.3 32.5 30.4 46.8 12.8 14.9 18.4 25.0 52.2 19.3 54.1 35.2 40.0 65.4 26.1 21.9 26.9 32.2 16.6 9.8 45.1 56.5 25.8 30.5 31.0 28.5 34.4 17.5 24.8 37.4 38.7 9.6 36.3 26.4 22.0 23.6 49.8 22.1 26.2 19.6 4.7 30.3 42.9 17.5 10.6 34.2 40.5 38.2 27.4 24.9 27.4 36.1 27.5 10.6 48.8 13.1 26.6 25.9 39.3 21.6 23.2 24.6 92.8 19.9 31.5 46.2 29.7 SH2B1 "FLJ30542, SH2B" ENSG00000178188 "SH2B adaptor protein 1" Q9NRF2 16 28846600-28874212 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060663, HPA076175" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Centriolar satellite, Cytosol" "HPA060663: , HPA076175: AB_2686782" "unprognostic (3.60e-2)" "unprognostic (1.94e-2)" "unprognostic (8.94e-2)" "unprognostic (2.27e-1)" "unprognostic (3.27e-1)" "unprognostic (3.27e-3)" "unprognostic (6.10e-2)" "prognostic favorable (9.40e-4)" "unprognostic (3.94e-2)" "unprognostic (1.18e-1)" "prognostic favorable (4.38e-4)" "unprognostic (1.39e-2)" "prognostic favorable (2.81e-6)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.60e-4)" 36.7 57.4 53.8 32.8 54.8 38.6 39.5 58.6 75.2 58.5 42.8 59.7 46.4 54.9 20.9 39.4 54.3 30.0 52.9 53.6 47.0 62.1 44.6 35.6 39.2 49.0 47.8 69.4 53.4 55.2 70.1 20.9 48.8 57.7 28.5 29.1 49.2 36.8 58.2 40.6 57.1 24.8 38.1 63.4 51.9 48.8 51.4 36.5 71.6 50.6 25.2 47.1 44.9 58.4 29.9 43.2 32.3 41.7 33.3 28.2 26.9 30.4 17.1 23.4 25.3 29.0 49.2 27.4 41.7 24.5 20.2 46.4 21.3 33.9 13.2 35.9 27.6 24.4 111.3 45.0 25.2 24.8 22.4 39.4 27.2 32.9 13.3 40.0 27.4 27.8 39.8 39.1 31.3 40.3 37.2 36.4 41.9 15.6 17.3 62.3 19.4 46.1 27.2 22.2 36.9 49.7 14.7 42.4 22.3 19.1 33.4 26.5 38.8 26.9 22.5 23.8 23.6 74.0 40.2 30.9 41.8 43.0 27.5 3.3 1.4 0.6 2.0 1.1 1.9 1.6 1.6 1.4 1.1 1.7 1.2 1.1 2.1 0.6 1.1 1.9 1.8 0.9 53.8 54.8 58.6 75.2 53.6 47.0 49.0 47.8 48.8 38.1 51.4 58.4 14.1 6.4 13.7 37.5 13.9 10.8 15.9 15.4 22.8 26.7 17.4 13.8 18.4 17.2 15.7 22.0 33.3 16.6 12.8 31.1 15.6 9.5 2.2 11.0 11.0 12.7 27.6 7.8 25.6 12.9 8.2 15.0 19.4 11.4 6.3 20.1 13.9 8.9 12.2 28.6 26.8 24.7 14.2 8.7 7.2 5.4 22.1 10.8 3.6 13.1 10.7 18.1 22.6 21.6 19.0 12.8 24.9 23.7 10.5 10.4 26.3 10.2 12.5 28.9 26.3 12.9 15.7 9.9 12.8 17.4 11.1 13.7 15.3 20.4 28.4 12.3 SH3BGRL2 ENSG00000198478 "SH3 domain binding glutamate rich protein like 2" Q9UJC5 6 79631329-79703655 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 161.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.3;Excitatory neurons: 86.5;Intestinal goblet cells: 87.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 50.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 11.1" "Lineage enriched" "Detected in many" 10 "granulocytes: 11.1" "Cell line enhanced" "Detected in many" "CACO-2: 81.6;HEL: 41.8;OE19: 99.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047486 Approved Supported Nucleoplasm NA NA 2000000 "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA047486: AB_2680065" "unprognostic (3.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (2.28e-2)" "unprognostic (4.21e-1)" "unprognostic (7.77e-2)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (6.92e-2)" "unprognostic (6.53e-3)" "unprognostic (2.78e-1)" "unprognostic (7.94e-2)" "prognostic favorable (2.24e-4)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.33e-1)" 26.4 6.9 18.8 7.5 18.6 1.7 21.6 15.6 27.5 22.3 15.1 50.5 35.2 9.9 24.7 55.1 17.8 23.2 6.8 21.4 21.8 15.7 53.1 12.7 5.5 26.7 22.0 4.1 23.3 31.5 16.6 24.0 28.1 26.2 47.9 26.0 161.7 11.4 4.8 11.3 35.6 15.8 24.1 6.6 68.9 2.1 24.2 4.8 59.1 10.1 10.7 12.7 19.7 22.5 8.5 1.5 7.6 1.6 6.7 5.6 18.0 0.5 5.6 1.9 4.0 81.6 16.3 0.1 11.4 0.5 1.6 3.9 7.0 9.2 6.7 0.0 10.2 41.8 1.8 15.8 2.8 1.7 1.1 3.1 7.3 5.8 3.3 2.7 23.8 0.0 16.8 0.0 0.7 1.3 0.0 0.2 6.5 99.7 2.8 0.0 2.2 0.2 2.0 27.3 20.3 22.3 0.5 2.4 0.6 10.3 0.4 3.5 13.6 5.2 3.4 0.1 4.9 12.0 6.0 0.0 0.9 0.0 1.6 11.1 0.2 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1.0 2.2 0.0 0.0 0.1 0.0 8.8 18.8 18.6 15.6 27.5 21.4 21.8 26.7 22.0 28.1 24.1 24.2 22.5 83.2 6.4 24.8 20.9 0.9 2.2 4.6 3.3 2.2 13.5 14.8 9.9 6.1 52.9 21.4 22.0 8.4 40.4 1.7 156.3 0.0 14.8 18.1 14.3 3.7 33.8 12.6 7.4 86.5 13.0 3.7 4.6 81.1 21.0 0.0 2.0 44.6 69.6 4.1 13.5 38.1 87.8 4.1 2.9 2.1 20.3 0.6 21.6 16.0 11.2 4.6 8.6 0.0 33.7 24.9 15.0 76.0 4.5 1.3 19.7 48.7 11.3 24.6 12.2 0.0 3.7 4.7 2.5 1.2 21.5 0.9 52.7 1.0 1.8 67.2 29.9 SH3BP5L KIAA1720 ENSG00000175137 "SH3 binding domain protein 5 like" Q7L8J4 1 248810446-248825915 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.7;eosinophil: 4.1;neutrophil: 4.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038067, HPA038068" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA038067: AB_2675814, HPA038068: AB_10670651" "unprognostic (2.48e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (4.41e-1)" "unprognostic (2.78e-1)" "unprognostic (2.27e-3)" "unprognostic (1.99e-3)" "unprognostic (5.84e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-3)" "unprognostic (1.50e-2)" "unprognostic (1.13e-1)" "unprognostic (2.05e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-2)" "unprognostic (4.66e-2)" 9.6 10.5 18.0 10.1 18.7 9.0 7.7 17.3 21.0 8.8 13.9 12.2 13.5 10.5 7.8 15.8 10.0 8.0 14.1 19.4 15.8 9.5 10.5 9.2 11.3 17.0 16.7 8.6 10.0 12.0 5.9 11.4 16.9 9.1 7.3 5.3 11.9 11.6 30.6 18.4 12.4 9.9 15.8 12.3 9.9 9.5 17.1 13.8 8.1 17.8 10.2 9.0 9.1 18.3 23.2 14.7 18.5 21.2 25.7 17.1 24.6 51.1 17.4 29.2 21.8 14.3 20.0 11.6 29.7 44.1 7.3 24.6 17.9 22.1 15.0 25.4 6.3 18.6 16.4 11.9 15.8 20.4 21.9 14.4 23.4 33.0 12.9 20.7 19.6 21.4 33.0 12.0 20.2 7.9 19.7 16.5 32.4 25.5 36.9 21.9 13.0 23.5 20.5 10.6 21.1 29.2 15.6 19.3 17.9 14.0 21.0 42.4 27.5 36.9 15.7 14.7 80.2 30.5 34.3 10.5 26.8 23.5 15.4 7.7 1.2 4.1 0.7 0.8 0.7 0.6 1.0 0.6 1.1 0.6 0.3 0.3 4.6 0.3 0.3 0.4 0.2 0.8 18.0 18.7 17.3 21.0 19.4 15.8 17.0 16.7 16.9 15.8 17.1 18.3 5.2 0.0 2.0 5.9 4.3 4.6 2.1 2.9 4.0 8.3 6.1 5.0 9.4 1.5 2.3 11.0 0.0 9.6 4.7 15.1 1.9 8.8 1.3 10.5 5.4 6.0 7.7 6.9 6.5 6.0 5.2 4.9 7.7 6.1 0.0 9.0 6.1 10.0 6.0 8.4 5.7 8.4 2.0 5.3 4.5 1.0 4.4 5.6 3.6 3.7 7.1 4.7 6.2 6.0 6.4 10.6 8.1 5.7 5.4 3.0 13.8 9.2 5.1 3.5 0.0 3.7 5.8 8.8 7.0 7.0 4.7 11.4 6.3 5.4 7.3 3.3 SHD ENSG00000105251 "Src homology 2 domain containing transforming protein D" Q96IW2 19 4279266-4290722 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 10.0;heart muscle: 17.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 137.5;Hepatocytes: 57.3;Intestinal goblet cells: 54.6;Paneth cells: 78.8;Proximal enterocytes: 43.1;Undifferentiated cells: 49.4" "Cancer enhanced" "Detected in some" "glioma: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 178 "plasmacytoid DC: 17.8" "Lineage enriched" "Detected in single" 178 "dendritic cells: 17.8" "Group enriched" "Detected in some" 45 "RH-30: 58.4;SH-SY5Y: 193.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017955 Uncertain Uncertain "Centriolar satellite,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite, Cytosol" "HPA017955: AB_1856828" "unprognostic (2.41e-3)" "unprognostic (7.68e-3)" "unprognostic (4.77e-3)" "unprognostic (3.67e-2)" "unprognostic (3.48e-2)" "unprognostic (3.42e-1)" "unprognostic (6.53e-2)" "unprognostic (1.43e-1)" "unprognostic (5.93e-2)" "unprognostic (3.73e-1)" "unprognostic (2.47e-2)" "unprognostic (3.76e-1)" "unprognostic (3.48e-1)" "unprognostic (1.21e-1)" "unprognostic (5.21e-2)" "unprognostic (9.69e-2)" "unprognostic (8.16e-4)" 0.0 0.1 4.2 0.6 3.6 0.7 0.0 7.0 8.6 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.1 17.8 2.4 9.6 0.0 1.5 0.0 0.6 7.4 6.4 0.0 0.0 0.1 0.2 0.0 5.6 0.0 0.3 0.6 0.1 0.0 0.4 0.0 0.2 0.0 4.6 0.1 0.0 0.1 10.0 0.1 0.0 1.7 0.3 0.1 0.0 6.0 0.0 0.0 0.7 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.4 0.0 0.0 0.2 58.4 0.1 0.0 0.0 0.5 193.2 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 4.2 3.6 7.0 8.6 2.4 9.6 7.4 6.4 5.6 4.6 10.0 6.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 0.0 0.0 6.9 0.0 0.0 0.0 0.0 1.8 21.7 137.5 1.9 0.0 0.1 0.1 0.0 0.2 13.2 5.3 2.8 0.0 0.6 0.4 0.0 0.1 8.9 0.0 0.7 57.3 0.4 10.1 4.2 54.6 0.0 0.6 0.0 0.4 0.0 0.6 0.0 1.0 0.2 0.9 0.0 9.0 0.3 0.0 78.8 0.0 0.0 0.0 43.1 0.0 0.0 0.4 0.0 2.5 0.1 0.0 2.9 0.0 0.0 4.4 0.8 0.0 49.4 0.0 SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 116.9;prostate: 73.9;urinary bladder: 62.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.0;Hepatocytes: 79.2;Proximal enterocytes: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA037690: AB_2675613, HPA037691: AB_2675614" "unprognostic (2.50e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.45e-2)" "unprognostic (3.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.33e-2)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.22e-2)" "unprognostic (2.91e-2)" "unprognostic (2.88e-2)" "unprognostic (2.26e-3)" 9.3 2.4 25.2 2.6 32.0 0.2 8.2 28.9 26.9 12.6 10.4 20.5 6.1 11.3 2.1 5.1 8.4 6.7 7.6 20.2 23.6 10.7 116.9 10.5 0.6 42.1 30.9 5.6 16.2 4.9 6.8 11.8 33.3 73.9 11.1 3.4 7.0 15.2 1.7 1.5 16.6 3.9 26.1 2.3 10.9 1.7 31.2 0.6 6.9 1.3 0.5 62.4 9.3 55.7 8.6 5.1 0.9 0.8 1.4 4.0 9.0 9.1 7.7 7.0 7.8 11.2 5.7 1.5 12.5 4.9 3.8 0.8 3.1 5.7 4.3 9.5 11.0 0.3 8.7 10.5 4.1 0.7 3.1 1.7 3.0 4.9 3.0 4.8 4.8 0.1 7.3 8.1 6.1 4.8 0.2 4.0 1.4 6.7 8.1 0.5 0.0 0.8 1.2 24.4 5.7 1.5 8.8 0.7 4.9 4.5 5.2 2.9 4.5 8.1 11.7 1.1 11.5 9.2 6.8 0.1 7.9 0.0 2.5 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 25.2 32.0 28.9 26.9 20.2 23.6 42.1 30.9 33.3 26.1 31.2 55.7 18.3 25.6 22.3 18.9 1.8 1.3 15.4 2.3 3.4 3.7 9.3 5.5 2.2 30.0 11.3 9.2 10.4 6.8 1.0 135.0 1.9 6.0 0.9 7.1 17.3 18.1 22.8 2.7 3.0 10.7 4.8 6.1 33.6 15.1 8.2 9.0 25.0 79.2 6.6 16.8 1.0 28.6 0.0 8.7 5.5 1.1 4.7 4.6 0.0 23.4 8.1 19.9 3.1 6.6 37.5 7.1 53.6 4.9 3.6 31.6 65.5 3.5 9.1 13.3 26.3 2.8 5.1 7.6 5.1 1.8 2.0 2.9 2.5 1.4 35.5 17.3 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 104.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 58.0;Cardiomyocytes: 59.5;Distal enterocytes: 102.4;Paneth cells: 53.0;Proximal enterocytes: 51.6;Undifferentiated cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 88.6;ASC TERT1: 91.3;HSkMC: 98.9;OE19: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" NA NA 2200000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 18.7 17.3 16.8 11.8 21.6 3.7 15.9 26.9 19.8 13.0 38.9 97.8 34.3 7.1 34.3 13.6 19.3 16.7 43.8 16.1 27.1 62.1 43.4 20.6 5.8 25.3 23.7 5.7 17.3 45.3 14.4 11.8 24.7 20.4 104.4 6.2 18.4 15.3 26.7 13.0 35.8 10.4 23.0 9.1 19.0 10.3 24.9 3.7 54.0 33.3 6.7 16.8 7.8 26.3 8.9 14.0 8.0 34.6 88.6 91.3 20.9 16.8 24.0 4.3 2.6 10.9 61.4 5.5 24.2 21.5 9.4 17.3 12.8 18.7 4.2 26.0 3.9 8.6 3.7 11.1 41.8 0.7 7.2 98.9 24.9 11.4 17.3 58.5 30.6 11.0 7.1 37.5 14.8 16.5 0.2 0.6 5.0 97.7 28.5 3.2 0.2 8.4 51.4 12.1 2.4 5.1 46.5 18.6 8.0 24.0 36.8 3.2 34.1 23.6 4.3 26.5 4.0 9.4 7.5 0.7 8.3 4.6 9.8 7.6 2.9 0.1 0.4 2.1 0.3 0.5 1.3 0.6 1.9 0.7 1.7 1.1 0.5 0.2 3.7 0.5 0.6 1.8 16.8 21.6 26.9 19.8 16.1 27.1 25.3 23.7 24.7 23.0 24.9 26.3 4.2 19.2 58.0 11.8 2.4 3.2 6.3 6.7 7.4 6.5 10.1 4.3 59.5 12.8 9.4 36.8 0.0 7.6 0.6 102.4 9.8 15.2 14.0 9.1 9.3 6.9 14.5 5.2 15.0 3.8 8.8 7.5 12.8 14.0 1.3 3.9 8.9 30.0 4.5 5.0 9.1 31.0 4.1 3.5 1.6 12.0 3.1 4.3 3.6 6.5 4.5 1.9 1.0 8.0 6.7 5.2 53.0 1.2 3.9 7.4 51.6 26.2 11.9 1.8 0.0 4.9 7.9 14.8 9.6 12.2 5.3 6.7 2.0 8.9 63.6 7.1 SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.7;Inhibitory neurons: 87.3;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 59.6" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: AB_2677832, HPA045480: AB_2679342, HPA074988: " "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (5.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.31e-2)" "unprognostic (5.48e-2)" "unprognostic (3.11e-1)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (5.43e-2)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (4.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-2)" 2.2 3.0 6.0 6.6 3.0 2.9 5.1 10.4 16.2 4.8 2.6 10.6 18.4 3.3 1.3 4.9 4.8 3.9 6.2 28.9 2.0 6.4 3.4 5.7 6.8 4.2 4.1 2.9 9.7 3.3 3.2 1.4 3.5 5.3 7.0 5.0 8.4 3.5 6.5 11.1 18.1 1.8 1.6 7.3 9.1 4.3 5.6 3.8 10.0 7.3 5.5 4.3 3.6 5.5 34.4 59.6 7.3 9.3 4.3 4.3 4.9 14.5 12.2 9.4 8.8 20.6 19.5 19.5 12.2 12.4 7.9 7.6 6.7 27.1 10.4 6.7 3.3 5.3 5.5 6.5 8.3 3.7 5.5 3.3 14.1 17.5 37.3 13.9 10.8 5.6 3.9 4.1 16.6 10.6 5.0 5.1 6.0 27.2 15.8 10.8 5.9 2.9 20.7 29.1 17.3 9.3 16.0 27.1 2.2 3.9 18.0 3.5 23.2 15.6 5.5 48.4 22.6 5.4 10.0 6.6 20.1 4.9 20.6 0.1 0.1 0.4 0.1 0.2 0.0 1.1 0.1 0.2 0.1 1.5 0.1 0.5 0.1 0.3 1.5 0.3 0.1 0.1 6.0 3.0 10.4 16.2 28.9 2.0 4.2 4.1 3.5 1.6 5.6 5.5 4.8 6.4 10.1 41.4 24.5 12.0 5.2 10.4 6.2 21.9 22.6 12.1 5.2 22.8 10.8 23.9 14.6 2.1 9.3 93.7 3.9 7.2 4.5 19.8 4.8 5.4 25.2 10.8 61.1 15.3 1.4 3.7 40.2 16.5 2.5 4.8 6.4 23.5 3.5 33.7 87.3 46.3 20.3 5.1 13.9 9.2 2.1 8.3 5.4 50.6 7.1 3.0 5.2 99.5 58.7 13.4 38.7 1.9 12.8 6.6 50.0 21.1 19.1 5.7 6.6 4.5 3.6 1.7 5.1 8.9 16.1 0.8 5.1 1.7 30.4 5.6 SIRT6 ENSG00000077463 "Sirtuin 6" Q8N6T7 19 4174109-4182566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Distal enterocytes: 199.2;Paneth cells: 129.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049729, HPA071776" Supported Supported Nucleoplasm,Vesicles No No "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA049729: AB_2680865, HPA071776: AB_2686445" "unprognostic (4.58e-1)" "unprognostic (3.41e-3)" "unprognostic (1.36e-1)" "prognostic favorable (2.85e-4)" "unprognostic (2.28e-1)" "unprognostic (4.14e-2)" "unprognostic (2.93e-3)" "unprognostic (8.32e-2)" "unprognostic (1.86e-1)" "unprognostic (6.13e-2)" "unprognostic (7.27e-3)" "unprognostic (4.42e-2)" "unprognostic (5.84e-2)" "prognostic favorable (9.13e-4)" "unprognostic (5.17e-2)" "unprognostic (1.63e-1)" "prognostic favorable (2.58e-4)" 8.2 12.0 10.4 7.8 10.6 10.4 8.6 10.3 15.1 10.5 8.7 23.6 10.0 10.6 2.4 12.3 9.2 3.5 10.0 10.7 10.2 13.7 11.0 8.9 7.1 11.2 10.3 7.5 14.1 5.2 13.3 4.3 10.5 12.7 7.5 1.9 9.3 5.0 8.0 11.8 14.2 2.6 9.8 15.3 9.8 6.0 12.1 4.9 10.1 2.7 3.9 9.9 9.7 10.6 25.7 16.8 8.3 10.4 6.5 6.2 12.9 12.0 8.9 10.1 8.8 11.2 9.5 16.0 12.9 8.1 9.1 15.9 4.6 12.9 1.6 30.8 10.0 6.8 9.7 10.3 14.3 17.4 25.2 7.9 10.4 10.3 6.4 7.7 8.7 15.0 15.2 35.3 5.4 19.2 23.9 18.3 14.5 9.3 15.2 18.9 7.7 18.8 9.7 11.4 11.0 18.1 11.0 10.2 24.1 3.2 10.2 23.0 12.2 10.4 10.5 36.9 17.4 45.6 25.7 18.4 20.8 28.1 12.7 5.3 13.1 12.2 10.8 16.3 6.4 9.6 7.5 8.7 14.3 10.1 6.4 6.1 11.8 5.6 13.5 11.9 12.6 8.5 10.4 10.6 10.3 15.1 10.7 10.2 11.2 10.3 10.5 9.8 12.1 10.6 9.2 12.8 7.3 5.9 13.8 10.3 10.3 32.3 9.6 12.6 6.6 6.3 3.2 7.2 18.4 5.5 18.8 24.1 7.1 199.2 13.7 32.2 1.9 6.2 7.9 11.8 26.4 9.5 8.9 26.7 24.2 9.3 19.9 9.2 5.7 5.6 13.6 6.8 24.0 13.5 10.4 29.1 18.3 11.7 10.1 2.6 11.5 15.0 5.4 1.9 27.0 15.2 14.4 3.5 6.3 32.5 129.7 8.2 10.3 9.7 28.2 14.3 11.0 13.8 0.0 7.2 11.3 7.4 9.6 13.3 12.6 25.6 10.6 7.9 30.9 11.9 SIRT7 ENSG00000187531 "Sirtuin 7" Q9NRC8 17 81911939-81921323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027284, HPA028246, CAB037261, HPA053669" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear speckles" "CAB037261: AB_1079989, HPA027284: , HPA028246: , HPA053669: AB_2682224" "unprognostic (8.15e-3)" "unprognostic (3.24e-2)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.46e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (1.97e-5)" "unprognostic (3.03e-1)" "unprognostic (2.10e-1)" "unprognostic (2.46e-2)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (4.34e-3)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (2.16e-2)" 8.8 8.0 6.8 7.4 7.3 23.2 8.6 7.5 8.6 12.5 7.4 17.3 12.9 7.0 1.9 42.1 8.0 5.4 6.4 6.9 6.7 11.5 14.2 9.6 11.8 7.6 7.0 6.0 12.8 5.4 6.9 4.2 7.4 9.8 5.8 0.6 14.1 3.7 6.2 22.4 17.1 3.6 7.0 18.7 17.9 13.3 7.6 9.4 7.9 3.7 7.2 10.8 18.0 7.6 26.5 21.7 2.8 9.5 6.9 6.4 17.0 13.1 10.8 15.1 14.1 18.7 20.7 11.8 9.9 7.3 9.6 18.8 10.5 8.1 4.9 10.2 22.9 10.4 10.7 29.7 20.4 13.6 20.5 6.5 25.0 14.5 11.9 6.4 11.3 6.5 11.3 5.8 7.2 20.9 14.6 19.5 6.8 40.6 22.3 9.7 5.5 11.1 14.7 17.4 11.1 14.6 15.0 35.9 17.7 5.0 15.1 32.1 9.0 6.8 14.9 12.9 24.2 9.5 3.2 9.0 16.6 18.4 11.3 4.5 2.6 22.2 2.8 3.8 0.9 4.5 2.1 2.3 1.4 7.0 2.0 0.7 4.4 1.8 3.3 2.1 1.2 1.5 6.8 7.3 7.5 8.6 6.9 6.7 7.6 7.0 7.4 7.0 7.6 7.6 15.2 12.8 12.2 12.4 41.4 38.0 25.8 21.1 28.5 23.4 27.4 19.0 4.4 18.6 18.7 18.4 56.3 31.1 62.8 99.0 9.8 22.4 21.8 28.8 14.0 15.4 20.4 16.0 14.3 13.6 33.2 12.4 152.9 37.0 11.4 20.1 15.0 16.0 26.1 30.3 10.6 34.6 28.5 26.4 33.5 14.1 14.3 29.4 24.9 5.6 47.3 14.7 71.1 6.6 13.8 52.7 74.5 10.1 33.2 29.1 74.7 16.0 29.6 39.1 0.0 12.5 15.5 41.3 37.4 52.4 55.5 49.3 50.8 17.9 44.6 53.9 SLC17A4 KIAA2138 ENSG00000146039 "Solute carrier family 17 member 4" Q9Y2C5 6 25754699-25781199 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "gallbladder: 16.3;intestine: 31.9;liver: 47.3;pancreas: 22.7" "Group enriched" "Detected in some" 5 "Cholangiocytes: 94.4;Distal enterocytes: 133.5;Hepatocytes: 41.8;Paneth cells: 44.1;Proximal enterocytes: 51.2" "Group enriched" "Detected in some" 6 "liver cancer: 11.0;renal cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "RPTEC TERT1: 1.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "cerebellum: 1.5" HPA055564 Approved NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055564: AB_2682852" "unprognostic (6.52e-2)" "unprognostic (5.64e-3)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (1.19e-3)" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (7.27e-3)" 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 20.6 28.7 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 3.7 47.3 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.1 0.2 0.0 26.7 0.0 0.0 0.0 0.0 0.0 31.9 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 94.4 0.0 0.0 0.0 0.0 0.0 133.5 0.0 8.3 0.8 0.0 0.0 0.0 13.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 41.8 0.1 0.0 0.0 11.7 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 44.1 0.0 0.0 0.0 51.2 1.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 11.5 0.0 SLC20A1 "Glvr-1, GLVR1, PiT-1" ENSG00000144136 "Solute carrier family 20 member 1" Q8WUM9 2 112645939-112663825 "Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Phosphate transport, Symport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 353.3;Paneth cells: 261.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 522.4;U-87 MG: 507.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019279, HPA035834" Approved Approved "Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB019279: , HPA035834: AB_2674809" "unprognostic (1.81e-1)" "unprognostic (2.18e-1)" "unprognostic (5.38e-2)" "unprognostic (4.03e-3)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.56e-5)" "unprognostic (1.50e-2)" "unprognostic (3.38e-2)" "unprognostic (2.32e-2)" "unprognostic (1.39e-1)" "unprognostic (7.43e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.44e-5)" "unprognostic (6.85e-2)" "unprognostic (1.09e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-3)" 36.1 11.7 16.2 33.2 24.3 74.6 15.6 27.8 26.3 11.8 25.0 53.6 14.4 13.7 8.4 15.0 14.5 26.4 21.8 20.7 19.8 22.1 49.0 29.2 37.1 25.5 20.7 9.2 30.7 10.4 15.9 29.7 25.2 13.3 21.9 52.3 12.8 9.3 19.7 14.5 28.4 15.0 18.6 29.5 20.2 15.7 24.5 27.2 15.9 7.5 27.5 40.8 13.3 21.2 69.0 55.5 71.1 57.8 52.9 128.8 54.4 181.6 215.3 79.1 102.2 85.0 164.9 124.0 97.5 67.7 305.0 70.5 78.8 138.0 114.8 68.5 80.4 105.5 57.1 81.3 78.2 61.2 178.9 66.0 53.8 279.1 193.9 522.4 102.2 52.9 199.5 126.3 346.7 26.8 83.9 235.9 119.3 31.8 147.6 77.8 63.5 34.9 114.5 312.8 64.4 60.8 91.7 54.9 127.9 31.4 56.0 42.9 223.6 143.5 94.7 50.8 142.4 52.1 143.7 102.2 507.2 57.9 178.3 13.4 33.5 30.1 52.8 59.8 59.4 8.3 22.2 38.4 25.4 5.0 17.5 27.6 14.7 50.2 37.2 41.8 14.6 33.9 16.2 24.3 27.8 26.3 20.7 19.8 25.5 20.7 25.2 18.6 24.5 21.2 61.7 12.8 25.9 42.4 40.3 112.8 59.1 38.7 104.7 60.0 41.9 31.6 49.6 32.9 35.3 9.2 210.6 44.7 119.1 353.3 13.7 18.1 1.5 86.0 34.3 48.2 35.7 53.2 47.3 14.0 13.5 61.5 96.4 167.8 25.3 20.6 41.0 58.1 28.2 20.2 27.2 85.8 32.6 58.5 86.2 3.3 3.7 80.5 26.6 19.7 42.8 31.8 66.9 18.6 26.1 26.9 261.6 4.9 59.8 34.0 156.3 5.2 59.6 84.6 0.0 36.9 25.9 8.5 18.7 119.5 61.8 74.3 70.4 19.0 96.5 90.3 SLC22A18AS "BWR1B, BWSCR1B, ORCTL2S, p27-BWR1B, SLC22A1LS" ENSG00000254827 "Solute carrier family 22 member 18 antisense" Q8N1D0 11 2887344-2903575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 17.7;kidney: 11.1;liver: 14.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 163.3;Paneth cells: 124.4;Proximal enterocytes: 75.7;Proximal tubular cells: 104.0;Syncytiotrophoblasts: 80.7;Undifferentiated cells: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 7.0" "Group enriched" "Detected in many" 8 "dendritic cells: 3.9;granulocytes: 4.0;monocytes: 7.0" "Cell line enhanced" "Detected in some" "A549: 9.4;CAPAN-2: 9.4;MCF7: 18.8;OE19: 8.4;SK-MEL-30: 35.8;WM-115: 14.8" HPA068288 Enhanced Approved Nucleoplasm No NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA068288: AB_2685969" "unprognostic (1.43e-1)" "unprognostic (9.21e-2)" "unprognostic (3.36e-1)" "unprognostic (8.05e-2)" "unprognostic (1.33e-3)" "unprognostic (3.16e-2)" "unprognostic (5.14e-3)" "unprognostic (9.76e-2)" "unprognostic (1.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.10e-2)" "unprognostic (1.48e-2)" "unprognostic (9.52e-2)" "unprognostic (1.77e-1)" "unprognostic (2.39e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" 3.2 0.6 0.5 2.2 0.6 0.2 0.7 0.5 1.7 0.7 0.5 17.7 13.4 0.8 0.4 1.2 0.4 1.7 0.3 0.6 1.0 11.1 14.9 0.6 0.4 0.9 0.9 0.4 0.3 0.0 0.3 2.3 1.1 0.8 10.2 0.3 1.8 0.1 0.1 1.1 9.7 0.7 0.8 0.7 1.6 0.5 0.8 0.1 0.3 0.0 0.1 0.7 0.9 1.1 1.2 9.4 0.3 0.5 0.0 0.0 0.9 0.5 0.4 0.0 0.2 2.2 9.4 0.0 0.8 0.0 0.6 0.5 0.0 0.3 0.0 0.4 0.1 0.0 0.8 5.8 0.7 0.0 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.5 0.0 0.9 0.0 18.8 0.0 0.4 0.2 8.4 0.3 0.3 0.0 1.0 0.8 0.0 0.1 0.3 0.9 0.4 35.8 0.2 0.0 0.9 1.9 0.0 0.7 0.3 0.2 0.0 0.0 0.2 0.2 2.6 14.8 4.0 7.0 1.2 0.2 3.9 0.1 0.0 0.1 0.2 3.9 0.0 0.0 0.1 1.6 0.4 2.9 0.0 0.6 2.4 0.5 0.6 0.5 1.7 0.6 1.0 0.9 0.9 1.1 0.8 0.8 1.1 0.6 0.0 0.5 0.0 1.3 0.5 1.1 6.3 1.2 0.0 1.2 0.9 0.4 1.5 2.7 7.3 0.0 19.5 0.4 163.3 9.8 1.7 0.1 0.1 0.3 0.7 9.1 3.2 0.4 0.8 9.8 1.4 2.6 0.5 1.3 0.0 2.9 22.7 17.7 0.0 0.1 26.2 6.1 6.3 5.5 0.2 0.3 6.4 3.6 0.0 4.6 0.0 0.0 0.0 0.1 2.4 124.4 0.0 0.0 1.0 75.7 104.0 1.0 0.0 0.0 0.0 0.6 0.1 0.4 2.1 1.1 80.7 0.9 0.8 48.5 2.5 SLC22A5 "CDSP, OCTN2, SCD" ENSG00000197375 "Solute carrier family 22 member 5" O76082 5 132369710-132395613 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 56.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Proximal enterocytes: 56.2" "Cancer enhanced" "Detected in all" "renal cancer: 8.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 34.7;SiHa: 37.8" "Low region specificity" "Detected in some" HPA063062 Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA063062: AB_2684934" "unprognostic (3.88e-1)" "unprognostic (1.69e-1)" "unprognostic (2.19e-2)" "prognostic favorable (2.87e-5)" "unprognostic (5.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.50e-2)" "unprognostic (9.24e-2)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (7.36e-4)" "unprognostic (3.53e-2)" "prognostic favorable (8.36e-4)" "unprognostic (1.12e-2)" "unprognostic (2.98e-2)" "unprognostic (2.17e-2)" "unprognostic (1.17e-2)" 5.3 6.6 7.5 2.0 7.9 0.9 4.9 7.8 7.8 5.0 14.4 12.4 13.7 4.0 11.1 3.9 8.4 4.1 14.2 7.3 8.0 26.7 7.8 3.2 1.2 7.8 7.8 5.6 8.2 17.9 11.0 4.2 7.4 9.1 9.4 3.7 6.4 11.2 56.1 6.0 16.9 2.5 7.5 2.5 6.0 3.8 8.0 2.1 5.4 22.3 1.8 5.0 5.0 7.8 6.1 14.4 0.9 11.3 4.4 2.1 19.3 2.7 2.9 4.5 6.2 10.7 12.2 2.9 6.0 2.6 13.1 14.3 9.4 7.0 5.3 3.6 11.6 1.5 34.7 4.9 7.3 2.4 2.4 2.0 12.9 3.1 15.8 7.6 1.2 5.2 6.8 1.8 4.4 10.4 3.6 2.4 1.0 10.5 6.2 1.3 0.0 15.9 13.5 15.2 4.8 3.3 37.8 28.9 7.6 2.9 13.5 3.1 0.7 0.7 3.9 9.5 3.3 6.0 12.8 0.1 2.9 5.9 2.7 0.0 2.0 0.0 1.1 1.0 1.2 0.6 1.1 1.4 3.1 0.6 1.1 1.4 0.2 0.8 0.3 0.2 2.1 1.0 7.5 7.9 7.8 7.8 7.3 8.0 7.8 7.8 7.4 7.5 8.0 7.8 3.0 9.6 8.2 23.5 3.8 7.6 7.5 4.7 13.1 6.7 16.9 5.3 5.6 21.5 5.5 16.5 12.5 23.6 3.2 63.9 1.9 9.8 2.0 13.7 10.3 2.6 7.2 1.7 11.9 5.2 5.5 5.6 16.3 26.6 0.0 6.1 2.9 8.6 4.2 10.1 11.1 14.3 8.2 6.7 1.6 2.8 6.5 5.9 5.4 17.8 1.3 9.4 0.0 7.1 4.2 6.4 26.3 4.1 4.8 14.2 56.2 22.2 9.4 7.1 0.0 17.7 3.8 8.4 2.8 9.6 6.3 8.2 4.0 0.3 18.0 9.0 SLC25A23 "APC2, FLJ30339, MGC2615" ENSG00000125648 "Solute carrier family 25 member 23" Q9BV35 19 6436079-6465203 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 238.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.2;Proximal enterocytes: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009675, HPA050883" Approved Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA009675: AB_2668252, HPA050883: AB_2681260" "unprognostic (3.51e-1)" "unprognostic (1.53e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.05e-2)" "unprognostic (3.65e-3)" "unprognostic (3.43e-2)" "unprognostic (1.31e-3)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (1.30e-1)" "unprognostic (3.25e-1)" "prognostic favorable (1.10e-12)" "unprognostic (8.95e-2)" "unprognostic (3.20e-1)" "unprognostic (5.44e-2)" "unprognostic (4.22e-1)" 28.8 38.0 144.8 12.0 238.7 0.8 18.0 77.5 200.1 32.1 72.0 94.4 39.3 41.8 24.0 64.7 36.6 21.4 79.0 206.5 95.1 45.0 38.5 24.0 9.2 108.8 98.2 33.6 24.2 58.8 22.2 4.7 109.5 35.0 49.1 41.2 68.9 40.0 90.8 33.5 40.5 65.5 82.7 11.9 41.3 9.5 101.4 7.2 60.7 78.2 31.2 55.8 31.1 115.8 58.2 22.9 32.2 101.9 42.3 18.6 14.9 17.0 26.4 31.0 37.2 58.2 37.1 32.2 40.0 41.3 34.1 48.0 66.3 39.0 24.3 0.1 58.6 23.2 46.7 46.2 39.2 1.6 52.5 53.3 33.4 27.6 12.0 62.9 32.8 34.7 68.8 39.4 6.2 41.6 20.7 32.8 23.6 61.0 71.1 10.0 8.8 49.4 83.3 10.2 2.4 31.9 11.7 70.8 30.0 34.8 37.1 50.1 11.7 9.8 41.8 2.6 11.2 7.3 10.7 28.3 4.5 54.2 15.6 0.5 0.0 0.0 2.0 0.0 0.4 1.0 1.1 0.9 0.2 0.4 1.5 1.4 0.0 0.3 0.0 0.4 1.3 0.4 144.8 238.7 77.5 200.1 206.5 95.1 108.8 98.2 109.5 82.7 101.4 115.8 6.2 9.6 20.9 11.8 7.0 10.5 8.8 11.5 12.0 13.1 18.9 15.6 39.5 47.1 10.0 46.0 8.4 1.4 4.5 164.2 19.6 54.7 15.9 8.2 6.4 8.0 13.8 1.3 24.7 28.5 1.8 10.2 12.8 17.5 7.0 17.9 16.1 38.0 2.7 8.4 17.9 34.5 10.2 3.0 2.6 71.2 19.0 1.4 17.8 12.2 1.0 28.7 4.1 17.1 12.6 55.5 57.9 29.3 17.6 13.6 106.8 28.7 6.4 22.0 13.1 12.1 12.7 0.5 4.6 34.1 23.3 0.8 5.2 39.5 34.2 30.3 SLC25A24 "APC1, DKFZp586G0123" ENSG00000085491 "Solute carrier family 25 member 24" Q6NUK1 1 108134043-108200849 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal enterocytes: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028519, HPA063636" Enhanced Enhanced Mitochondria NA NA 19000 "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA028519: AB_10603890, HPA063636: AB_2685068" "unprognostic (1.94e-2)" "unprognostic (7.30e-3)" "prognostic favorable (1.01e-4)" "unprognostic (7.11e-2)" "unprognostic (1.64e-2)" "unprognostic (2.91e-1)" "unprognostic (8.54e-4)" "unprognostic (1.51e-2)" "unprognostic (7.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-3)" "unprognostic (6.18e-2)" "unprognostic (6.76e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 10.0 6.2 0.8 5.3 0.7 3.8 8.2 0.6 1.3 12.5 0.8 13.5 11.4 6.6 3.2 6.0 6.7 6.8 4.9 0.7 0.8 6.3 1.6 9.1 5.1 0.8 0.7 5.9 4.2 8.2 2.8 9.4 0.9 4.0 16.0 6.7 6.7 4.6 3.7 4.3 12.3 8.7 0.6 5.7 6.9 3.2 1.0 5.0 7.1 4.5 4.9 10.1 7.0 0.7 38.2 8.9 28.8 8.6 17.9 23.4 11.4 13.0 17.0 25.1 27.4 11.3 12.9 0.0 10.3 28.7 10.9 14.1 7.9 24.0 35.1 7.9 4.4 2.4 13.4 5.2 14.9 6.1 4.9 17.6 17.0 15.0 18.5 16.8 19.6 5.7 6.2 13.0 32.2 28.7 3.7 1.4 14.3 17.3 8.1 5.7 33.9 12.6 16.9 22.8 5.0 8.7 17.4 14.9 17.5 27.5 13.3 10.7 10.5 13.8 6.2 23.2 15.0 3.0 2.3 0.0 5.0 11.8 8.2 0.4 0.5 0.4 0.3 0.5 0.3 0.1 0.2 0.2 0.4 0.4 0.1 0.3 0.1 0.2 0.7 0.3 0.4 0.1 0.8 0.7 0.6 1.3 0.7 0.8 0.8 0.7 0.9 0.6 1.0 0.7 33.9 54.5 27.8 5.5 24.2 15.6 20.4 20.6 17.1 14.7 25.5 16.8 15.5 17.2 33.5 18.4 8.4 7.1 16.3 126.7 21.5 31.2 3.2 62.0 46.7 28.6 18.1 6.7 18.0 36.9 60.2 23.2 40.2 61.7 22.2 20.9 29.6 1.2 54.1 10.1 14.9 43.2 18.3 51.8 32.8 2.9 19.6 50.0 23.2 16.9 44.7 12.7 11.3 14.6 20.8 67.6 51.2 18.0 9.7 14.3 54.4 24.9 55.2 33.9 52.6 27.2 26.5 6.2 2.4 24.8 14.9 6.2 23.9 41.8 59.1 33.8 SLC25A43 ENSG00000077713 "Solute carrier family 25 member 43" Q8WUT9 X 119399336-119454478 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 30.7;Oligodendrocyte precursor cells: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035188, HPA078530" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA035188: AB_10602400, HPA078530: " "unprognostic (6.05e-3)" "unprognostic (1.48e-1)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (4.99e-3)" "unprognostic (1.59e-2)" "unprognostic (3.26e-2)" "unprognostic (2.74e-2)" "unprognostic (7.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.80e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.06e-8)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "unprognostic (1.96e-2)" "unprognostic (4.92e-2)" 10.6 2.6 3.1 7.3 3.4 1.8 9.3 3.3 4.1 8.2 5.4 14.0 14.2 5.0 3.4 21.4 5.3 4.3 5.0 3.2 3.6 7.7 10.6 10.2 5.5 4.3 3.5 6.0 5.9 6.9 1.9 8.3 3.9 4.6 15.5 0.5 10.8 4.6 1.6 16.3 12.8 8.8 3.5 4.9 8.9 2.1 3.6 3.6 4.2 4.5 11.3 7.9 11.3 3.8 32.4 23.3 1.9 9.2 30.0 44.5 12.2 17.9 21.7 13.8 13.2 12.4 16.0 4.0 10.2 47.4 41.1 23.2 18.2 16.0 12.4 28.5 5.4 11.3 7.4 16.4 19.3 10.6 11.7 18.8 28.3 22.5 19.8 18.9 16.6 6.1 2.3 17.1 15.7 58.9 0.1 15.9 10.3 16.6 35.1 3.2 0.0 4.6 22.3 10.9 1.5 0.0 23.0 47.8 29.1 7.3 8.5 11.0 24.2 22.2 7.1 25.0 28.0 0.4 14.2 8.3 22.3 17.8 19.7 0.0 3.5 0.2 0.9 4.9 1.7 4.4 1.8 2.9 6.0 3.7 0.9 1.8 0.1 6.4 11.2 1.6 1.5 1.6 3.1 3.4 3.3 4.1 3.2 3.6 4.3 3.5 3.9 3.5 3.6 3.8 8.3 6.4 9.7 30.7 8.0 7.8 7.3 8.9 9.6 0.2 6.1 6.6 1.6 2.8 5.6 3.7 0.0 11.9 9.1 21.8 9.8 4.5 0.0 0.9 7.6 6.9 7.3 3.4 10.3 8.9 7.1 11.8 9.7 1.8 8.2 2.1 6.4 5.8 10.3 0.0 6.2 9.6 4.1 7.1 13.6 0.4 8.1 7.5 10.6 1.0 11.9 0.2 9.2 36.7 1.4 13.9 11.4 5.7 2.8 5.4 19.8 9.6 2.0 0.4 0.0 7.8 9.2 0.5 2.3 19.8 13.9 6.8 6.8 1.0 12.2 5.8 SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 212.0" "Group enriched" "Detected in many" 4 "Distal enterocytes: 2026.2;Glandular and luminal cells: 684.5;Syncytiotrophoblasts: 808.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 66.1;RPTEC TERT1: 151.7;TIME: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041957: AB_10795646, HPA058090: AB_2683602" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-2)" "prognostic favorable (7.29e-4)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (1.19e-1)" "unprognostic (7.43e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" 5.2 30.7 2.2 7.8 2.3 2.5 9.2 9.5 3.8 6.3 4.0 212.0 12.9 9.3 22.8 10.7 5.0 5.5 2.8 2.2 3.5 4.9 1.7 7.3 4.0 3.8 3.4 4.8 3.4 37.7 7.1 34.0 3.5 12.2 189.6 20.8 35.8 18.4 3.9 7.8 16.1 9.3 3.8 3.7 3.3 4.2 3.9 4.2 4.5 3.7 5.9 4.7 3.0 3.4 9.5 8.6 10.5 17.3 12.6 8.8 2.5 8.9 8.0 7.0 8.5 44.7 5.1 7.4 66.1 9.5 16.8 6.8 10.0 20.5 12.4 6.0 6.4 9.3 6.7 5.2 9.4 17.3 15.2 9.8 11.8 11.7 15.2 17.3 16.8 9.0 2.4 7.1 29.6 3.0 6.6 9.1 3.2 3.2 13.5 9.5 16.3 3.9 151.7 41.6 3.2 8.1 15.6 3.6 27.2 8.1 7.3 10.0 80.4 16.0 11.8 14.2 10.7 5.2 7.3 4.3 14.7 20.6 23.5 4.9 0.5 0.3 0.9 0.3 1.1 0.5 0.5 0.8 0.7 0.5 0.8 0.9 0.3 1.1 1.6 0.7 1.1 0.5 2.2 2.3 9.5 3.8 2.2 3.5 3.8 3.4 3.5 3.8 3.9 3.4 47.4 44.8 11.3 3.3 8.5 4.6 13.2 22.9 7.4 17.1 23.8 14.6 7.8 7.2 24.2 33.1 16.7 219.2 11.5 2026.2 1.9 6.1 32.7 237.0 92.3 29.8 21.1 16.6 5.4 9.9 7.7 21.5 5.1 684.5 90.0 29.6 17.2 2.0 30.4 6.7 7.9 52.5 20.3 15.3 11.8 15.7 17.4 17.4 90.7 17.8 19.6 15.2 15.5 16.6 6.0 12.1 177.4 12.4 15.2 15.1 91.7 5.1 26.6 84.5 0.0 18.7 13.9 8.7 11.4 73.9 5.1 808.9 14.0 26.3 208.9 5.5 SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1120.4" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 2328.4" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036055 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" 1.1 0.0 0.0 19.7 0.0 0.0 59.5 0.2 0.1 0.3 0.0 1120.4 576.9 0.9 15.3 0.5 0.8 17.8 0.0 0.0 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.1 878.8 0.1 0.0 129.9 0.0 0.1 118.5 15.0 0.0 0.0 1.3 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 165.9 4.2 0.0 0.3 0.0 0.0 0.0 51.4 41.7 0.3 34.3 0.0 0.0 0.0 0.0 0.0 2328.4 0.0 0.0 6.4 1.8 0.1 0.3 14.3 0.0 110.2 0.0 0.0 0.1 0.0 0.2 26.7 0.2 0.0 0.1 0.0 0.0 114.3 32.5 0.0 0.0 0.0 0.6 0.3 0.1 0.0 89.9 0.0 0.0 0.0 101.6 182.1 0.0 503.4 0.0 0.0 0.3 388.9 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 0.0 86.0 0.1 SLC26A6 DKFZp586E1422 ENSG00000225697 "Solute carrier family 26 member 6" Q9BXS9 3 48625723-48635493 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.7;Intestinal goblet cells: 34.0;Paneth cells: 40.9;Proximal enterocytes: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048363 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA048363: AB_2680371" "unprognostic (1.54e-1)" "unprognostic (4.94e-2)" "unprognostic (3.34e-1)" "unprognostic (3.15e-2)" "unprognostic (2.15e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.92e-4)" "unprognostic (2.39e-1)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (4.09e-1)" "unprognostic (9.66e-3)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.58e-2)" 5.6 6.8 4.8 5.2 5.2 18.1 5.5 5.1 6.5 9.3 5.4 28.0 8.2 7.4 3.6 5.2 6.6 3.7 8.1 4.7 5.0 19.6 7.6 9.5 3.9 5.6 5.1 7.3 11.4 3.6 5.5 5.5 5.9 12.4 21.6 4.1 5.8 4.2 9.5 6.7 22.4 5.6 5.2 12.5 26.8 5.6 5.6 3.8 6.3 6.1 3.2 6.6 7.9 6.2 8.5 8.9 13.2 15.0 39.9 19.8 11.2 13.7 17.7 25.8 27.4 17.6 7.6 12.0 4.6 11.6 28.7 11.2 12.1 12.5 7.2 9.3 12.0 10.8 29.6 34.3 29.4 5.2 16.5 27.4 44.0 17.7 12.4 22.1 8.0 12.4 8.6 13.2 6.2 9.8 10.4 27.0 18.5 23.0 17.9 5.2 4.8 14.5 18.8 7.9 3.3 6.2 17.7 21.3 25.2 17.9 11.2 19.2 6.9 11.6 9.2 15.0 31.7 15.7 17.8 5.6 9.7 20.5 28.4 6.8 11.1 2.3 3.0 10.8 2.7 0.9 1.8 1.9 9.0 0.2 1.0 1.5 1.5 0.6 10.1 5.1 3.4 5.0 4.8 5.2 5.1 6.5 4.7 5.0 5.6 5.1 5.9 5.2 5.6 6.2 4.3 3.2 5.9 10.7 2.1 3.2 2.6 8.0 5.7 2.1 3.8 2.7 6.6 1.5 3.8 1.8 14.6 9.3 2.4 69.7 0.0 2.9 1.2 1.3 3.2 5.1 20.4 4.0 2.0 6.3 15.0 4.0 13.3 2.7 0.0 3.1 4.2 6.3 7.0 5.0 2.1 34.0 10.2 5.3 7.4 0.9 3.7 6.3 5.4 1.9 5.8 1.6 6.2 2.5 2.5 5.8 40.9 9.4 5.8 2.0 43.6 6.2 3.7 6.9 0.0 1.3 4.5 2.9 6.9 2.4 3.4 10.5 3.8 13.5 26.8 1.0 SLC28A2 "CNT2, HCNT2, HsT17153, SPNT1" ENSG00000137860 "Solute carrier family 28 member 2" O43868 15 45252234-45277846 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 92.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.6;Paneth cells: 35.7;Proximal enterocytes: 43.4;Undifferentiated cells: 48.9" "Cancer enhanced" "Detected in many" "stomach cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046068, HPA055623" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA046068: AB_2679523, HPA055623: AB_2682866" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-3)" "unprognostic (5.46e-2)" "unprognostic (1.13e-1)" "unprognostic (6.85e-2)" "unprognostic (6.31e-2)" "unprognostic (1.59e-2)" "unprognostic (1.61e-1)" "unprognostic (6.40e-4)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (1.28e-2)" "unprognostic (2.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-2)" "unprognostic (8.95e-2)" 0.1 0.3 0.4 0.7 0.4 0.1 0.0 0.3 0.4 2.6 0.0 9.5 68.0 0.5 0.4 0.1 0.1 9.8 0.3 0.3 0.1 3.5 0.8 0.1 0.3 0.4 0.0 0.3 0.3 0.0 0.0 0.6 0.4 0.1 34.6 0.7 0.2 0.0 0.3 0.3 92.3 0.0 0.1 0.2 22.8 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.4 0.3 0.1 0.4 0.0 0.4 0.1 0.2 0.6 0.5 0.0 8.1 1.6 0.9 0.1 0.4 0.4 0.0 2.9 0.3 0.0 0.7 8.6 4.5 0.0 2.1 12.3 0.3 19.6 0.0 0.1 0.7 1.0 0.4 1.0 13.9 2.7 1.8 0.0 2.7 1.0 4.6 1.2 8.8 0.7 0.7 0.3 0.9 1.7 1.5 14.5 0.0 0.3 0.4 0.4 0.0 1.3 0.0 0.0 0.2 1.0 2.1 2.0 2.0 0.0 35.7 0.7 0.4 0.2 43.4 1.2 4.6 6.6 0.0 0.3 0.2 2.4 2.1 0.0 0.3 4.7 1.3 0.2 48.9 0.2 SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219958647 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 23.9;liver: 33.5" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Distal enterocytes: 44.3;Early spermatids: 38.3;Hepatocytes: 21.1;Late spermatids: 36.1;Paneth cells: 14.4;Proximal enterocytes: 13.6" "Cancer enriched" "Detected in some" 14 "liver cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.0;HEL: 1.5;K-562: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 42: Non-specific - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA064547: AB_2732715" "unprognostic (7.88e-2)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-3)" "unprognostic (6.96e-2)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-2)" "unprognostic (5.10e-2)" "unprognostic (3.10e-3)" "unprognostic (4.47e-7)" "unprognostic (3.16e-1)" "unprognostic (6.11e-2)" "unprognostic (6.19e-3)" "unprognostic (5.72e-2)" 0.0 0.0 6.0 0.0 6.1 0.3 0.0 4.4 7.6 0.0 7.4 3.8 23.9 0.0 0.0 0.0 0.0 0.4 0.0 5.9 5.7 0.0 33.5 0.0 0.0 5.4 5.9 0.2 0.0 0.0 0.0 0.0 5.6 0.1 5.0 0.4 0.0 0.0 0.7 0.1 8.9 0.0 4.5 0.0 0.0 0.7 6.5 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.2 0.2 0.3 0.3 0.3 0.2 0.1 0.1 6.0 6.1 4.4 7.6 5.9 5.7 5.4 5.9 5.6 4.5 6.5 4.7 0.0 0.0 0.0 20.2 0.2 0.3 0.0 0.2 0.0 0.3 0.2 0.0 1.2 1.5 0.1 0.0 0.0 0.1 0.0 44.3 0.0 0.2 38.3 0.0 0.0 1.0 0.0 2.7 4.3 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.4 21.1 0.1 0.0 4.3 0.6 0.0 0.6 0.3 36.1 1.2 0.0 1.8 9.4 0.0 3.1 0.0 3.0 3.3 0.0 14.4 1.5 0.0 0.0 13.6 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.9 0.0 0.1 0.3 0.0 1.3 0.8 0.0 SLC35A3 ENSG00000117620 "Solute carrier family 35 member A3" Q9Y2D2 1 99969351-100035634 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015253 Uncertain NA NA "Cluster 6: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA015253: AB_1857106" "unprognostic (1.05e-1)" "unprognostic (2.69e-1)" "unprognostic (1.57e-3)" "unprognostic (5.89e-2)" "unprognostic (9.64e-2)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (4.02e-2)" "unprognostic (2.59e-2)" "unprognostic (1.47e-1)" "unprognostic (1.76e-3)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-3)" "unprognostic (2.32e-1)" "unprognostic (2.73e-2)" "unprognostic (9.34e-2)" 11.6 7.3 4.3 10.4 5.1 11.4 18.3 6.6 5.8 19.1 10.0 53.3 49.7 9.6 11.4 14.4 13.1 13.5 5.5 4.1 4.7 21.3 37.3 11.5 8.0 4.7 4.6 8.1 11.5 19.8 4.8 10.2 5.1 23.0 53.8 6.9 22.0 11.6 4.9 10.8 41.4 8.8 4.5 7.9 33.4 2.8 4.9 18.9 24.9 6.1 8.9 10.5 10.2 6.3 28.3 7.6 6.7 7.1 14.8 12.9 26.7 24.5 14.8 9.4 13.6 4.9 15.1 15.1 30.0 14.3 13.3 16.0 12.7 11.0 21.6 18.7 9.4 13.7 10.7 11.8 9.2 22.1 1.6 6.8 12.1 11.5 22.2 11.3 11.1 11.9 23.0 21.9 19.3 7.1 14.6 11.4 8.2 16.0 24.9 4.5 20.4 9.4 17.1 16.0 8.6 4.8 17.0 32.3 13.7 6.2 19.7 16.6 13.0 14.3 13.0 32.0 13.3 12.9 16.2 11.2 23.0 13.5 6.1 4.4 2.1 1.1 2.2 2.1 2.5 2.5 2.2 2.6 1.7 1.8 2.7 2.3 0.6 4.3 1.7 5.0 2.8 1.9 4.3 5.1 6.6 5.8 4.1 4.7 4.7 4.6 5.1 4.5 4.9 6.3 23.5 80.1 28.6 12.4 17.8 25.0 21.6 30.5 18.8 15.7 33.9 15.4 8.8 27.1 50.5 55.2 20.9 19.4 51.4 211.0 7.9 18.1 4.4 49.4 22.4 20.5 19.8 9.7 24.4 15.3 30.5 17.0 43.3 46.3 17.1 19.5 20.7 49.3 14.2 10.1 26.6 110.6 22.4 17.8 17.1 2.1 13.4 14.2 8.8 23.4 18.0 19.0 14.4 30.2 46.7 21.7 82.8 13.2 25.6 43.3 112.4 25.3 92.6 25.1 6.6 14.4 17.7 16.2 8.3 21.2 29.7 23.3 23.8 12.8 116.4 48.4 SLC35D1 "KIAA0260, UGTREL7" ENSG00000116704 "Solute carrier family 35 member D1" Q9NTN3 1 66999350-67054148 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.6;Early spermatids: 73.5;Hepatocytes: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.91e-2)" "unprognostic (3.69e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.63e-1)" "unprognostic (6.53e-2)" "unprognostic (2.49e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (2.12e-3)" "unprognostic (6.39e-2)" "unprognostic (6.75e-2)" "unprognostic (2.07e-1)" "unprognostic (7.65e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-1)" "unprognostic (4.08e-3)" "unprognostic (3.20e-1)" 4.9 6.6 4.0 7.8 4.6 8.9 5.2 4.1 4.2 7.6 9.9 26.0 15.9 5.7 4.9 5.3 5.0 6.4 3.7 3.8 4.2 12.5 74.7 3.7 7.5 4.7 6.1 7.8 7.5 8.1 5.6 9.5 4.8 7.2 26.8 12.3 4.4 5.7 7.5 9.8 16.3 6.9 4.0 4.2 12.9 6.2 5.8 10.1 6.4 5.0 8.6 7.3 6.8 7.0 8.3 4.7 14.2 12.0 14.4 16.6 16.8 18.4 24.1 13.1 9.1 10.2 2.0 25.7 7.9 14.6 15.4 12.5 9.9 11.6 16.4 25.8 4.6 19.2 9.8 20.2 12.1 22.0 12.2 16.3 25.4 15.4 10.9 21.0 5.1 10.6 11.8 13.3 32.0 2.8 13.6 6.8 5.9 22.5 6.4 10.4 29.3 2.9 6.0 15.6 1.7 6.3 27.8 8.5 11.9 7.9 7.0 16.2 5.6 24.2 5.7 15.0 17.9 27.6 15.4 14.1 17.2 3.3 10.4 8.5 0.9 2.6 2.0 0.7 2.4 1.3 1.5 1.6 1.1 0.9 2.1 2.0 0.2 3.5 1.7 0.6 2.8 0.9 4.0 4.6 4.1 4.2 3.8 4.2 4.7 6.1 4.8 4.0 5.8 7.0 4.9 6.4 2.2 34.6 12.8 5.5 5.9 9.4 13.1 6.9 7.5 4.8 3.1 20.0 4.6 5.5 12.5 40.5 18.3 75.6 0.0 3.1 73.5 6.3 10.9 4.3 15.0 9.1 22.8 9.6 5.7 8.3 14.8 8.7 4.5 13.2 7.5 114.3 6.9 6.7 28.2 18.9 2.0 8.8 4.6 13.7 6.2 5.5 1.8 23.4 3.1 17.8 9.2 37.7 51.2 8.3 20.8 4.5 9.3 5.8 24.9 10.6 7.5 9.4 0.0 8.6 7.5 7.7 6.4 8.2 7.7 16.3 12.8 11.3 21.7 8.8 SLC35D2 "SQV7L, UGTrel8" ENSG00000130958 "Solute carrier family 35 member D2" Q76EJ3 9 96313444-96383711 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 117.2;Proximal enterocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 103.8;Hep G2: 132.3" HPA064047 Approved Supported "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA064047: AB_2685182" "unprognostic (3.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.16e-2)" "unprognostic (3.17e-1)" "unprognostic (8.86e-3)" "unprognostic (4.25e-3)" "unprognostic (2.24e-2)" "unprognostic (4.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-2)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (1.44e-1)" 14.7 8.8 13.5 14.4 20.6 11.4 16.4 17.8 20.6 16.5 12.3 49.1 65.1 14.9 12.1 13.7 14.6 20.6 12.2 14.3 16.0 32.1 56.4 19.2 12.4 25.5 19.7 17.3 31.4 16.4 7.2 25.5 22.1 14.2 46.4 4.3 13.0 11.0 3.9 9.4 65.8 13.9 16.6 10.0 43.1 7.2 20.1 7.5 29.5 6.9 11.7 17.2 13.1 27.8 33.2 27.6 15.8 30.2 20.3 37.3 27.9 14.7 30.2 21.6 17.5 60.4 103.8 0.6 24.5 13.5 49.9 47.6 22.2 21.8 18.7 16.4 16.8 11.3 9.8 132.3 32.5 0.1 0.0 32.2 27.6 16.3 48.7 51.0 46.7 0.0 22.3 0.4 23.7 27.2 0.3 0.1 13.2 67.5 28.5 0.1 0.0 0.0 54.4 21.3 5.5 35.9 11.9 24.8 68.5 53.3 16.4 24.7 41.3 14.5 16.2 21.2 13.8 0.0 0.9 0.1 30.2 0.1 20.4 1.2 0.9 0.6 1.3 1.1 1.6 0.7 2.1 2.9 1.2 0.9 0.7 1.4 0.1 1.8 2.1 0.2 3.9 0.5 13.5 20.6 17.8 20.6 14.3 16.0 25.5 19.7 22.1 16.6 20.1 27.8 14.5 9.6 11.0 12.1 4.3 5.2 8.9 2.1 1.8 1.1 15.1 13.1 7.2 27.1 4.6 12.9 2.1 28.1 12.9 61.7 11.7 8.1 0.2 21.0 14.0 12.6 9.6 1.3 0.8 24.5 45.1 9.5 20.4 31.6 4.5 20.0 13.2 43.2 20.5 1.7 1.1 42.0 4.1 23.0 9.7 0.6 10.8 17.7 17.8 20.6 8.9 10.2 7.2 11.1 117.2 25.4 43.5 6.0 6.3 15.5 67.0 23.6 6.7 3.6 13.1 6.8 11.2 1.4 4.4 8.6 5.4 26.5 14.6 7.0 34.9 17.9 SLC44A3 "CTL3, MGC45474" ENSG00000143036 "Solute carrier family 44 member 3" Q8N4M1 1 94820342-94895246 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 18 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "OE19: 35.9;RPTEC TERT1: 101.4;RT4: 69.5" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in all" HPA047433 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047433: AB_2680046" "unprognostic (8.06e-2)" "unprognostic (7.65e-2)" "unprognostic (4.63e-3)" "unprognostic (3.57e-2)" "unprognostic (1.53e-2)" "unprognostic (2.37e-1)" "unprognostic (1.14e-1)" "unprognostic (4.03e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-1)" "unprognostic (5.78e-2)" "unprognostic (2.44e-2)" "prognostic favorable (7.63e-5)" "unprognostic (9.09e-2)" "unprognostic (8.28e-2)" "unprognostic (5.95e-2)" "unprognostic (3.31e-3)" 2.2 8.8 15.7 6.2 15.3 0.1 8.1 17.9 16.9 8.8 14.0 31.5 26.1 7.2 6.6 9.4 8.0 10.9 3.9 14.8 17.0 29.3 6.3 10.3 0.8 20.7 16.4 1.7 27.0 5.2 15.0 3.4 16.4 10.8 35.4 4.3 23.4 7.7 0.2 6.0 28.0 2.8 17.6 0.9 29.3 2.5 15.7 4.9 5.2 0.6 2.2 22.1 6.5 18.3 23.4 3.2 0.8 0.0 2.5 3.2 15.9 0.4 3.4 0.8 3.7 21.4 5.8 0.0 15.4 0.4 6.9 7.7 3.5 5.5 1.4 0.0 4.1 0.0 1.2 1.7 1.1 0.0 0.0 9.9 5.1 1.6 0.0 6.3 0.4 0.0 0.0 0.0 1.4 3.4 0.0 0.3 1.0 35.9 0.8 1.8 0.7 1.3 101.4 69.5 10.4 17.0 1.0 10.8 7.8 7.3 6.2 0.7 0.0 0.5 3.5 1.5 0.2 0.0 0.0 0.0 2.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 15.3 17.9 16.9 14.8 17.0 20.7 16.4 16.4 17.6 15.7 18.3 0.4 25.6 6.7 26.1 0.6 3.1 27.8 14.6 4.0 0.7 15.6 8.3 5.7 37.1 22.7 12.9 0.0 15.9 0.1 18.2 15.6 33.4 32.5 12.8 3.2 1.3 16.3 0.0 1.4 27.8 0.8 3.8 16.3 22.5 1.3 5.3 0.7 2.1 1.3 0.0 4.6 32.2 20.3 0.3 0.4 5.3 5.0 0.8 5.4 2.8 1.0 17.0 0.0 5.5 2.0 38.3 36.5 10.9 0.0 12.9 22.8 38.6 11.4 0.2 0.0 9.6 3.4 0.1 0.2 10.2 3.8 6.7 0.8 4.1 42.8 30.3 SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.0;prostate: 83.0;stomach 1: 83.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 546.0;Exocrine glandular cells: 213.4;Intestinal goblet cells: 327.8;Paneth cells: 299.3;Proximal enterocytes: 267.7;Respiratory ciliated cells: 406.7;Undifferentiated cells: 259.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" 0.8 8.2 0.0 2.5 0.0 1.0 5.3 0.0 0.0 22.4 0.0 132.0 100.8 5.9 2.5 2.0 46.9 18.8 0.0 0.0 0.0 32.1 0.4 14.9 0.1 0.3 0.1 1.6 8.9 0.0 16.1 3.5 0.1 83.0 30.3 0.0 42.6 3.9 0.0 1.1 86.8 2.9 0.0 1.6 83.4 0.7 0.0 0.2 1.9 0.0 0.7 11.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 3.7 22.4 36.0 0.0 3.8 0.5 23.0 71.4 0.6 0.3 14.6 6.1 0.4 38.6 180.2 66.2 0.0 0.3 0.5 546.0 3.9 111.2 2.3 127.4 8.9 6.2 46.7 0.0 0.1 213.4 0.5 2.4 208.5 67.5 2.5 1.1 0.4 0.0 0.5 0.0 0.1 327.8 91.6 0.0 0.0 3.2 1.5 2.5 0.0 0.0 1.6 0.7 0.0 0.0 0.0 184.0 299.3 0.4 0.3 142.0 267.7 61.5 406.7 0.6 0.0 0.8 11.9 0.2 0.2 0.5 0.4 0.7 2.3 5.5 259.6 139.4 SLC52A2 "D15Ertd747e, FLJ11856, GPCR41, GPR172A, hRFT3, PAR1, RFVT2" ENSG00000185803 "Solute carrier family 52 member 2" Q9HAB3 8 144333957-144361286 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Host cell receptor for virus entry, Receptor" "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 149.0;PC-3: 167.6" "Low region specificity" "Detected in all" HPA063036 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA063036: AB_2684928" "unprognostic (7.80e-3)" "prognostic unfavorable (7.55e-4)" "unprognostic (2.15e-1)" "unprognostic (2.94e-1)" "unprognostic (3.09e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (7.74e-3)" "unprognostic (9.20e-2)" "unprognostic (2.24e-2)" "unprognostic (4.85e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.12e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" 29.7 31.6 13.7 5.4 13.4 5.6 27.8 15.3 18.5 21.7 14.5 35.7 9.4 23.0 8.0 33.3 17.3 3.2 26.4 13.5 14.5 29.2 16.9 24.6 5.6 15.0 14.9 15.6 41.6 5.3 24.5 7.7 14.6 22.2 5.7 1.3 29.8 6.3 13.5 30.4 29.6 4.3 14.0 34.8 31.4 31.5 15.1 4.0 21.7 2.7 4.1 24.9 21.2 14.1 38.7 65.0 7.5 17.9 19.3 12.3 37.3 28.1 18.9 26.5 24.6 57.9 42.3 16.3 42.3 27.5 20.7 42.6 18.4 25.3 9.8 18.3 34.5 26.3 31.3 50.1 51.7 9.4 29.4 14.8 34.7 27.4 24.4 19.2 15.8 16.2 40.9 23.7 18.7 149.0 15.6 38.0 17.9 51.5 167.6 29.8 8.9 44.9 30.6 34.4 25.9 29.4 31.1 44.1 35.7 9.9 27.8 18.7 20.2 20.9 46.9 48.2 37.9 9.4 13.8 12.4 37.8 26.6 25.7 0.5 4.2 9.2 5.6 5.9 3.8 3.3 3.9 5.6 4.5 9.8 3.6 2.6 1.1 5.2 7.5 7.6 5.7 1.5 13.7 13.4 15.3 18.5 13.5 14.5 15.0 14.9 14.6 14.0 15.1 14.1 31.9 6.4 8.7 5.5 24.3 31.2 27.0 41.5 12.0 11.1 30.6 17.0 3.1 12.8 34.4 12.9 2.1 85.0 36.3 81.8 0.0 62.3 3.3 11.6 16.6 24.3 17.4 7.8 3.2 66.9 92.1 22.2 42.3 21.5 10.2 16.6 18.9 5.5 52.4 11.8 3.7 56.3 36.7 13.5 27.8 5.8 12.8 21.4 30.2 2.8 40.7 14.3 19.6 7.1 2.4 85.1 46.7 19.9 43.3 54.7 52.4 14.5 11.7 10.8 19.7 12.1 31.1 34.0 40.2 20.2 36.1 52.5 24.8 23.4 65.6 36.7 SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.0;Distal enterocytes: 382.0;Proximal enterocytes: 235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 155.8;AN3-CA: 151.3;SK-BR-3: 156.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" 31.6 66.6 77.2 9.0 99.4 34.5 23.9 77.8 80.0 17.5 39.9 73.5 51.3 32.4 13.0 54.6 17.3 31.3 130.4 76.8 82.1 81.4 4.5 9.2 1.9 89.0 90.5 12.4 20.0 45.6 21.4 36.2 76.9 31.3 30.5 34.7 52.3 35.9 166.6 45.9 75.9 20.7 71.3 13.1 30.8 38.5 87.6 11.9 8.2 75.5 3.0 41.2 36.5 116.6 155.8 6.7 39.5 151.3 14.7 9.9 10.2 22.2 37.7 28.7 35.5 20.1 2.1 0.2 17.0 27.9 33.6 54.3 85.3 78.0 17.0 2.7 83.3 0.6 50.6 59.7 50.0 1.2 10.1 20.9 16.5 27.3 103.3 50.7 14.9 0.9 37.3 2.4 15.7 9.3 0.8 3.6 47.0 30.9 67.0 7.6 5.2 2.1 30.8 29.5 56.0 64.2 33.8 156.8 107.9 9.8 30.9 23.9 14.1 45.2 73.1 58.2 66.5 5.2 3.0 1.8 105.5 4.5 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 77.2 99.4 77.8 80.0 76.8 82.1 89.0 90.5 76.9 71.3 87.6 116.6 5.9 0.0 1.9 14.0 2.7 23.2 14.3 91.1 13.1 142.0 19.6 18.4 106.9 21.5 55.6 5.5 110.5 15.3 2.8 382.0 3.9 4.6 1.5 21.4 38.9 6.5 25.9 23.4 8.2 22.2 37.7 8.8 6.1 16.1 4.5 14.4 3.9 0.9 4.9 119.5 9.9 44.2 38.7 1.9 5.7 3.7 9.0 4.1 24.9 2.8 3.2 19.0 0.0 9.0 23.7 47.5 101.1 8.2 0.8 28.3 235.8 53.3 31.3 49.3 32.9 15.6 19.0 2.9 3.9 16.9 15.6 90.8 2.9 1.5 20.7 18.6 SLC6A9 GLYT1 ENSG00000196517 "Solute carrier family 6 member 9" P48067 1 43991500-44031467 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.4;skin 1: 46.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.7;Distal enterocytes: 17.8;Erythroid cells: 33.1;Ionocytes: 20.3" "Cancer enhanced" "Detected in all" "glioma: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.3;hTCEpi: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013977 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA013977: AB_1849835" "unprognostic (2.73e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (5.98e-2)" "unprognostic (6.83e-3)" "unprognostic (3.06e-2)" "unprognostic (9.72e-2)" "unprognostic (1.85e-2)" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (5.36e-3)" "unprognostic (1.59e-1)" "unprognostic (2.53e-1)" "unprognostic (1.20e-2)" 3.9 31.0 21.7 4.9 45.5 10.8 4.6 53.2 24.2 12.1 6.3 11.0 2.3 7.4 1.1 23.1 9.5 4.8 2.1 16.1 31.3 4.3 2.3 11.6 1.1 66.3 43.5 2.9 8.2 2.8 1.7 1.4 63.6 3.9 6.3 17.2 11.5 5.5 1.1 46.6 6.0 9.1 45.6 1.9 7.4 1.1 45.9 1.4 5.3 0.6 4.3 12.3 25.1 72.4 19.7 13.7 7.1 18.0 11.2 3.7 15.6 14.7 41.0 24.3 30.1 4.8 7.5 0.3 1.6 42.9 0.0 62.3 11.0 12.5 5.0 0.1 1.8 17.1 33.9 5.8 50.3 3.8 0.7 11.3 106.6 11.9 28.5 15.3 0.6 12.3 13.0 48.5 1.0 10.4 2.9 0.1 5.4 7.4 19.1 2.2 0.0 22.9 2.3 2.2 4.4 4.2 7.4 35.3 7.0 1.7 9.1 10.3 0.2 2.8 11.0 2.4 8.0 53.1 39.2 4.4 9.2 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 45.5 53.2 24.2 16.1 31.3 66.3 43.5 63.6 45.6 45.9 72.4 1.5 0.0 2.0 5.9 1.1 7.5 0.9 3.2 8.0 30.7 2.2 0.9 0.7 4.3 2.2 1.8 16.7 0.5 0.5 17.8 0.0 3.7 5.9 4.8 0.4 0.7 0.0 33.1 2.2 8.9 1.0 0.9 1.5 2.7 0.0 0.0 0.0 0.3 0.3 1.7 1.5 2.7 20.3 0.0 1.0 0.8 1.5 0.1 3.6 0.0 1.0 1.2 0.0 3.0 16.4 4.2 3.0 1.5 1.3 2.0 9.1 1.1 12.5 11.1 6.6 0.1 10.0 0.1 0.4 8.9 12.9 0.5 0.3 1.2 2.6 3.2 SLC9A1 "APNH, NHE1, PPP1R143" ENSG00000090020 "Solute carrier family 9 member A1" P19634 1 27098809-27166981 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 76.5;stomach 1: 65.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.5;Gastric mucus-secreting cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022371, HPA048532, HPA052891" Enhanced Supported "Plasma membrane" NA NA 21000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB022371: , HPA048532: AB_2680431, HPA052891: AB_2681981" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.70e-2)" "unprognostic (4.33e-3)" "unprognostic (3.18e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (3.44e-2)" "unprognostic (6.95e-2)" "unprognostic (2.05e-2)" "unprognostic (1.27e-2)" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-2)" 9.6 10.7 6.1 10.4 14.7 11.5 9.0 2.8 10.8 10.9 0.2 18.6 29.3 10.9 8.0 11.0 7.6 16.9 13.7 2.3 5.3 5.8 2.4 13.2 7.0 13.8 4.7 7.0 8.6 20.7 8.2 21.9 11.2 9.0 13.6 4.5 76.5 19.4 4.6 10.5 19.0 10.7 0.5 11.6 65.9 10.1 10.4 6.3 9.5 4.9 6.7 15.1 9.2 2.4 32.3 10.7 9.9 10.1 21.8 15.7 60.8 25.9 38.5 21.7 23.5 13.0 20.0 14.4 21.9 33.4 10.5 38.9 9.8 62.4 13.4 17.4 9.4 21.9 7.1 5.5 66.1 13.1 16.0 19.7 29.5 36.5 50.7 15.8 36.3 9.8 6.3 13.4 32.3 18.7 6.8 6.4 14.0 38.2 21.9 11.8 9.0 6.7 10.9 46.3 11.4 3.7 21.5 28.4 12.6 10.0 13.3 7.9 39.9 23.0 9.4 21.7 14.5 12.6 8.6 4.3 24.6 14.1 13.5 0.0 0.6 0.6 0.7 0.3 1.5 0.1 0.8 0.7 0.2 0.3 0.5 0.6 2.0 0.1 0.6 0.0 0.3 0.8 6.1 14.7 2.8 10.8 2.3 5.3 13.8 4.7 11.2 0.5 10.4 2.4 13.5 6.4 14.8 6.5 7.9 31.2 17.9 14.6 13.1 7.4 21.7 23.2 13.5 7.2 8.3 11.0 0.0 40.3 11.9 81.5 0.0 9.1 26.5 13.8 15.9 9.7 12.5 0.4 14.1 12.5 19.4 12.7 160.0 26.5 27.3 7.5 6.8 1.2 12.9 20.2 14.1 15.0 4.1 5.7 5.1 14.4 9.3 12.7 7.2 8.4 4.3 8.2 12.3 4.0 4.6 28.1 43.1 13.2 4.8 9.6 38.9 1.2 5.9 3.8 6.6 20.8 9.8 3.6 4.4 15.0 25.1 52.9 9.8 4.8 18.3 18.3 SLC9A2 NHE2 ENSG00000115616 "Solute carrier family 9 member A2" Q9UBY0 2 102619553-102711355 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;stomach 1: 26.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 41.3;Early spermatids: 46.5;Gastric mucus-secreting cells: 41.8;Intestinal goblet cells: 23.4;Late spermatids: 31.4;Paneth cells: 38.7;Undifferentiated cells: 29.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 10.0;OE19: 37.3;RT4: 16.9;SK-BR-3: 14.7;T-47d: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035121, HPA035122" Approved Supported "Cell Junctions" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA035121: AB_10602894, HPA035122: AB_2674477" "unprognostic (1.53e-2)" "unprognostic (8.05e-3)" "unprognostic (6.00e-2)" "unprognostic (3.00e-3)" "unprognostic (3.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.97e-1)" "unprognostic (1.40e-3)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "unprognostic (1.39e-2)" "unprognostic (1.70e-1)" 0.0 0.1 1.4 2.1 0.7 0.0 1.4 0.8 1.5 1.4 0.2 20.0 6.3 0.1 3.9 0.3 0.3 1.1 0.0 1.9 0.9 5.4 0.0 0.1 0.1 1.4 0.7 0.0 0.0 5.8 1.0 0.0 1.5 5.8 20.7 0.1 4.9 2.1 6.4 0.8 3.4 0.7 0.8 0.0 26.4 5.7 1.2 0.4 1.0 6.2 4.5 1.0 0.0 0.5 10.0 6.1 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 0.2 0.0 3.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 3.4 2.9 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 7.7 0.0 0.1 0.2 37.3 5.0 0.0 0.1 0.0 1.1 16.9 0.1 0.0 0.0 14.7 0.0 0.0 18.5 0.0 0.0 0.0 0.7 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.8 1.5 1.9 0.9 1.4 0.7 1.5 0.8 1.2 0.5 0.0 0.0 0.0 2.0 0.3 0.4 0.2 0.1 0.0 0.0 1.1 0.1 0.8 0.0 0.3 9.2 0.0 0.5 0.0 41.3 0.0 0.2 46.5 0.5 0.2 0.3 9.7 0.0 3.0 0.0 0.0 0.0 41.8 3.1 0.0 0.0 0.0 0.0 0.1 0.0 14.6 23.4 6.1 0.0 0.4 31.4 0.6 0.0 0.0 5.6 0.0 0.5 0.0 1.0 1.0 8.5 38.7 0.0 0.2 4.1 3.2 1.4 0.1 0.1 0.0 0.5 0.1 4.5 0.2 0.0 0.6 0.3 0.2 0.0 29.6 0.8 SMG5 "EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5" ENSG00000198952 "SMG5 nonsense mediated mRNA decay factor" Q9UPR3 1 156249224-156282825 "Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072651 Uncertain "Cytoplasmic bodies" No No "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cytoplasmic bodies" "HPA072651: AB_2686544" "unprognostic (2.09e-2)" "unprognostic (3.45e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (3.20e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.70e-9)" "unprognostic (1.28e-1)" "unprognostic (3.21e-3)" "unprognostic (6.90e-2)" "unprognostic (1.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (4.28e-1)" "unprognostic (8.77e-2)" "unprognostic (4.26e-2)" 25.2 43.2 44.5 22.0 46.5 46.7 23.7 43.6 46.0 25.6 42.1 35.4 27.3 27.5 24.6 37.3 27.1 18.8 58.8 42.0 42.8 43.4 47.5 32.7 25.8 49.9 48.3 25.7 28.3 46.3 39.0 26.5 46.9 35.2 22.0 35.3 26.8 23.8 62.8 36.4 32.3 28.0 44.4 33.8 33.4 27.7 50.3 29.4 29.9 43.3 24.8 31.2 25.9 53.3 53.4 45.8 54.8 40.9 52.2 29.5 79.0 54.0 48.2 80.0 67.7 116.2 67.4 48.1 61.6 64.8 63.7 62.8 97.3 68.3 51.4 54.5 80.9 55.6 45.8 64.2 67.6 58.8 54.5 37.4 66.7 76.9 81.5 41.2 52.1 70.4 77.0 47.1 56.9 54.5 48.3 47.5 110.9 97.0 94.6 77.2 41.8 51.1 52.1 63.4 73.4 61.1 68.5 100.6 61.8 71.9 86.8 124.3 44.0 55.4 61.6 59.1 79.6 71.7 17.9 89.1 48.8 57.8 71.7 1.6 3.7 5.2 3.8 3.9 3.1 2.9 2.9 2.8 2.4 2.5 2.5 2.7 4.1 3.0 4.2 2.4 2.0 3.6 44.5 46.5 43.6 46.0 42.0 42.8 49.9 48.3 46.9 44.4 50.3 53.3 9.1 16.0 13.4 21.9 16.8 14.7 7.8 7.3 17.6 12.8 14.7 9.8 39.5 18.6 9.6 20.2 33.3 17.8 10.4 44.8 7.9 12.3 2.8 14.1 9.1 12.9 22.7 9.9 23.9 14.5 10.7 9.4 35.2 16.1 12.7 18.4 9.7 21.6 12.4 18.5 21.4 20.3 8.2 14.4 8.6 5.5 8.4 11.1 5.4 19.7 13.5 11.2 7.2 12.1 24.2 17.9 24.2 7.2 17.9 14.3 23.7 15.5 12.8 12.6 6.6 9.2 10.5 8.5 7.8 16.9 12.1 17.1 14.0 11.4 23.6 15.4 SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.6;pancreas: 154.3;salivary gland: 147.2;stomach 1: 201.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2005.0;Intestinal goblet cells: 1223.5;Paneth cells: 1462.9;Proximal enterocytes: 1685.8;Respiratory ciliated cells: 686.7;Undifferentiated cells: 775.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 261.7;OE19: 247.3;RT4: 89.8;SCLC-21H: 70.7;SK-BR-3: 201.2" "Low region specificity" "Detected in many" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA077331: AB_2686834" "unprognostic (6.55e-2)" "unprognostic (4.12e-2)" "unprognostic (4.84e-2)" "unprognostic (3.69e-3)" "unprognostic (7.82e-2)" "unprognostic (3.84e-2)" "unprognostic (4.63e-2)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (3.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (1.73e-3)" 1.2 0.3 0.1 14.6 1.2 3.5 48.2 4.6 2.0 45.4 0.0 193.6 129.6 8.9 50.4 10.3 77.3 33.3 0.5 0.5 0.4 42.0 1.4 24.1 0.6 2.6 0.9 0.5 154.3 0.1 48.9 2.0 2.1 42.6 122.7 1.5 147.2 36.3 0.2 10.4 128.4 6.3 0.8 0.2 201.7 33.8 2.6 0.2 1.1 0.0 2.7 46.1 6.5 3.1 0.2 0.0 0.1 0.6 0.0 0.0 1.9 0.3 0.1 0.1 0.1 0.6 261.7 0.3 7.3 0.0 0.3 1.3 0.1 0.0 0.1 0.4 1.9 0.1 5.8 0.9 0.1 0.7 0.3 0.2 1.4 0.0 0.0 0.2 0.1 0.4 0.0 0.6 0.0 1.9 0.1 0.6 0.8 247.3 0.0 0.8 0.3 23.6 1.5 89.8 70.7 0.8 0.5 201.2 0.0 0.5 15.2 0.0 0.0 0.6 0.8 1.1 0.1 0.2 0.6 0.9 0.0 0.7 0.6 1.2 0.3 0.4 0.3 0.1 0.1 0.1 0.3 0.1 0.0 0.4 0.3 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.1 1.2 4.6 2.0 0.5 0.4 2.6 0.9 2.1 0.8 2.6 3.1 1.4 48.1 117.7 0.0 5.8 2.2 22.7 92.7 0.0 4.2 363.3 267.5 0.5 183.0 154.9 250.1 0.0 3.9 3.0 2005.0 25.4 259.8 40.1 430.4 26.5 4.4 470.3 0.0 0.5 381.9 0.4 4.7 438.8 258.3 18.4 0.1 0.4 0.2 0.4 1.7 0.3 1223.5 152.5 0.0 0.8 107.3 0.6 4.2 23.2 0.0 5.3 0.6 0.0 0.0 1.3 539.9 1462.9 1.2 1.0 29.5 1685.8 99.4 686.7 4.2 0.0 0.0 15.9 38.6 0.6 2.3 2.3 3.7 6.6 0.2 775.6 148.6 SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 131.3;Late spermatids: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 139.1;fHDF/TERT166: 144.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" 21.8 36.5 38.8 13.9 44.7 7.3 20.1 45.1 43.0 21.2 33.9 25.3 16.8 20.9 14.4 20.6 14.6 21.5 55.8 39.1 43.0 73.7 95.3 31.3 14.6 42.7 42.6 17.9 32.8 34.2 41.9 21.6 43.3 29.4 14.9 8.5 29.0 20.0 37.9 37.9 23.8 17.6 40.9 21.1 25.4 14.0 47.5 17.8 34.0 29.4 11.0 23.6 21.0 46.8 16.4 13.1 10.1 26.5 139.1 72.2 17.1 60.4 95.0 27.7 33.0 22.0 11.9 4.7 27.4 144.0 59.3 7.4 8.4 12.7 13.0 21.0 9.6 5.1 19.5 6.0 62.3 3.7 37.4 96.0 23.4 25.9 17.7 100.9 61.6 1.7 9.1 30.5 58.9 17.0 0.1 6.5 3.9 23.2 22.3 1.2 5.5 7.0 23.9 6.2 17.0 9.7 27.6 19.5 38.5 12.9 7.3 7.0 53.9 103.0 10.9 59.1 15.4 37.6 44.0 3.5 93.7 10.8 47.1 1.9 2.5 3.4 6.4 2.1 5.0 1.5 5.5 5.0 1.3 3.1 10.0 10.1 2.5 6.6 0.6 1.7 4.7 3.2 38.8 44.7 45.1 43.0 39.1 43.0 42.7 42.6 43.3 40.9 47.5 46.8 14.1 25.6 14.4 10.7 12.2 7.9 22.8 15.3 6.8 12.6 13.7 9.0 37.7 24.3 12.8 25.8 25.0 38.8 11.5 131.3 11.7 53.4 50.0 6.2 13.0 18.6 23.8 9.9 5.8 38.2 14.4 31.4 15.8 21.0 10.8 9.4 26.7 88.5 34.1 20.2 5.5 20.3 24.4 15.5 6.2 200.7 11.5 15.8 55.2 4.7 7.8 16.4 36.0 6.6 15.5 24.7 83.1 13.5 23.1 26.0 51.7 75.1 2.4 5.2 0.0 8.9 17.1 1.4 3.1 7.5 8.0 34.3 23.3 10.2 18.0 15.4 SMPDL3B ASML3B ENSG00000130768 "Sphingomyelin phosphodiesterase acid like 3B" Q92485 1 27935000-27959157 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.1;pancreas: 49.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.1;Ductal cells: 31.5;Paneth cells: 47.5;Proximal enterocytes: 37.4;Undifferentiated cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "eosinophil: 3.3;myeloid DC: 1.3;neutrophil: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.3;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "BEWO: 46.0;CAPAN-2: 35.3;NTERA-2: 27.6;RPMI-8226: 30.1;SK-BR-3: 45.9;T-47d: 33.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA030561 Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 400000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Golgi apparatus" "HPA030561: AB_10604095" "unprognostic (1.22e-2)" "unprognostic (4.45e-1)" "unprognostic (4.58e-3)" "unprognostic (3.83e-2)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.50e-1)" "unprognostic (2.68e-1)" "unprognostic (3.95e-1)" "unprognostic (6.02e-2)" "unprognostic (1.64e-1)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.48e-1)" "unprognostic (4.40e-2)" "unprognostic (3.09e-3)" 1.5 0.3 0.5 2.2 0.6 2.0 5.7 2.5 0.6 2.8 2.0 22.2 24.1 1.9 15.8 1.1 7.0 2.2 0.3 1.1 0.7 5.2 0.4 6.6 1.2 0.4 0.4 0.2 49.4 7.9 1.0 0.3 0.5 3.6 23.6 0.1 12.5 0.5 0.0 0.9 14.2 1.0 0.6 1.7 16.5 0.7 0.8 0.5 13.9 0.0 3.1 2.2 0.4 0.6 5.4 2.5 0.0 0.3 0.0 0.0 46.0 0.0 1.1 0.6 3.4 12.1 35.3 1.7 8.3 0.0 0.7 5.9 3.8 3.2 0.5 0.0 23.6 7.9 0.5 3.0 0.0 2.6 0.0 0.2 2.9 7.0 0.4 1.0 1.0 0.3 1.0 0.4 0.0 19.5 0.1 0.8 27.6 4.1 4.3 0.5 0.2 30.1 24.6 9.5 23.4 0.5 0.0 45.9 1.3 4.7 33.3 1.4 0.0 0.0 7.6 0.1 0.0 0.3 12.9 0.6 0.8 0.0 0.1 0.1 0.1 3.3 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.2 0.1 0.0 1.8 0.3 0.0 0.0 0.0 0.1 0.5 0.6 2.5 0.6 1.1 0.7 0.4 0.4 0.5 0.6 0.8 0.6 0.1 9.6 17.9 0.0 2.3 0.1 2.7 4.0 0.0 0.0 15.0 6.5 0.4 1.5 13.8 9.2 0.0 2.5 0.5 38.1 0.0 31.5 0.4 2.2 0.3 1.1 20.4 1.3 0.8 23.3 0.2 0.2 18.3 5.6 0.0 2.0 0.4 0.0 0.3 0.0 0.1 21.6 10.2 0.0 0.4 0.2 0.0 0.9 0.0 1.0 0.0 0.0 0.0 1.0 0.0 21.7 47.5 0.0 16.6 3.7 37.4 8.7 2.7 0.0 0.0 0.0 0.8 0.0 0.2 0.6 0.1 7.7 0.8 0.1 31.2 3.0 SNX15 ENSG00000110025 "Sorting nexin 15" Q9NRS6 11 65027439-65040572 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal enterocytes: 5.6;Enteroendocrine cells: 7.8;granulocytes: 8.2;monocytes: 7.9;Paneth cells: 8.0;Proximal enterocytes: 6.5;Undifferentiated cells: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038955 Approved Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Cytosol" "Vesicles, Plasma membrane" "HPA038955: AB_10672834" "unprognostic (2.00e-2)" "unprognostic (4.90e-2)" "unprognostic (3.93e-1)" "unprognostic (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (4.06e-3)" "unprognostic (4.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.09e-1)" "unprognostic (9.55e-2)" "unprognostic (8.93e-3)" "unprognostic (1.79e-2)" "unprognostic (8.84e-2)" "unprognostic (7.86e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.68e-4)" 17.1 13.3 17.3 10.2 18.5 10.5 15.3 19.4 19.2 16.6 9.0 22.5 15.3 15.8 6.4 14.9 12.9 7.4 15.0 18.4 17.1 17.0 10.1 11.9 9.3 19.3 18.2 14.8 12.7 10.7 9.4 7.3 16.1 12.9 8.8 5.8 12.3 10.9 25.7 17.5 16.8 8.9 16.1 10.8 16.4 5.3 17.8 9.4 10.6 15.5 7.4 18.0 14.9 18.5 31.1 22.3 14.7 14.2 17.3 12.4 7.9 10.0 13.6 23.3 21.3 17.6 23.7 30.7 16.7 17.4 29.3 16.8 16.8 15.2 9.8 47.0 14.0 15.8 18.2 30.2 18.3 10.7 24.5 10.6 22.2 24.7 14.5 13.0 14.1 22.6 27.0 19.6 12.5 18.8 29.2 36.8 15.5 12.0 21.9 23.7 8.4 34.0 17.6 6.7 25.6 19.2 25.3 23.0 23.2 9.7 23.4 18.6 27.5 23.5 22.9 24.1 14.7 20.9 38.3 30.3 23.2 14.5 8.4 9.2 13.6 13.6 7.6 16.2 6.2 8.9 7.8 6.8 9.4 8.7 5.6 5.1 2.1 4.3 23.6 6.4 8.3 7.3 17.3 18.5 19.4 19.2 18.4 17.1 19.3 18.2 16.1 16.1 17.8 18.5 0.3 0.0 3.3 0.0 0.8 1.0 0.1 0.4 4.0 0.0 0.5 0.3 0.4 0.0 0.2 0.0 0.0 0.4 0.1 5.6 0.0 4.8 0.0 0.1 0.2 0.9 7.8 1.3 0.0 3.1 0.6 0.4 1.1 0.1 8.2 0.4 0.7 0.1 1.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 7.9 0.2 0.0 0.0 0.0 3.9 8.0 0.4 1.1 0.0 6.5 0.6 0.7 0.4 0.0 0.7 1.0 0.0 0.0 1.5 0.4 0.4 1.1 0.2 5.6 0.1 SOCS6 "CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4" ENSG00000170677 "Suppressor of cytokine signaling 6" O14544 18 70289045-70330199 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;myeloid DC: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010189 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB010189: AB_661195" "unprognostic (1.76e-3)" "unprognostic (6.83e-3)" "unprognostic (8.90e-3)" "unprognostic (4.52e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-1)" "unprognostic (2.07e-1)" "unprognostic (7.93e-2)" "unprognostic (5.83e-2)" "unprognostic (1.75e-1)" "unprognostic (6.90e-2)" "unprognostic (8.19e-2)" "prognostic favorable (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (4.11e-2)" "unprognostic (1.80e-2)" 7.9 8.0 8.3 6.0 10.2 13.1 14.0 11.7 8.1 15.2 5.8 16.2 15.6 11.8 6.9 15.0 12.3 13.5 11.0 7.8 7.6 9.3 28.3 9.7 3.4 14.8 10.2 10.9 13.0 14.1 4.1 13.9 14.4 8.4 14.4 5.6 11.3 7.9 12.8 7.1 22.8 10.9 13.2 4.1 14.0 5.7 17.5 3.2 11.6 13.4 5.6 8.3 8.0 19.3 19.2 41.6 17.4 12.0 16.1 18.9 19.4 40.3 24.5 24.0 18.0 15.6 31.7 2.1 3.6 37.7 29.0 22.2 12.8 13.2 23.3 0.0 7.8 14.4 14.3 24.1 19.1 7.9 15.6 15.3 15.4 20.9 17.4 23.9 12.2 1.7 8.7 9.6 16.5 9.3 6.8 5.8 11.2 12.2 17.7 8.0 16.8 3.5 14.9 15.6 8.0 20.0 20.9 22.8 18.9 12.4 6.8 13.6 15.1 26.3 13.3 5.5 16.5 0.0 0.0 5.2 29.3 0.6 18.1 0.0 3.6 2.9 0.2 0.7 0.1 0.3 0.4 0.0 3.9 0.0 0.6 0.3 0.0 1.0 0.0 0.3 0.0 1.2 8.3 10.2 11.7 8.1 7.8 7.6 14.8 10.2 14.4 13.2 17.5 19.3 15.0 25.6 17.0 8.1 1.2 11.7 13.7 13.3 12.0 12.9 26.6 14.7 22.4 21.5 30.1 11.0 6.2 28.0 2.1 61.0 11.7 18.4 1.3 23.5 23.5 13.9 29.4 3.8 17.0 18.5 15.6 13.7 21.4 34.6 31.0 9.1 13.6 32.4 25.7 37.0 17.5 31.0 10.2 7.7 11.1 2.8 11.5 19.2 26.6 86.2 10.1 7.8 5.2 28.6 32.1 30.5 30.5 12.8 0.9 17.4 36.8 25.6 21.8 4.7 0.0 14.9 12.5 1.3 11.0 20.5 11.9 68.4 2.1 4.4 26.7 34.6 SPATA2 "KIAA0757, PD1, PPP1R145, tamo" ENSG00000158480 "Spermatogenesis associated 2" Q9UM82 20 49903391-49915529 "Predicted intracellular proteins" Necrosis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 45.2;Late spermatids: 62.5;Spermatocytes: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048581, HPA052224" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA048581: AB_2680449, HPA052224: AB_2681769" "unprognostic (4.02e-2)" "unprognostic (5.98e-2)" "unprognostic (8.26e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.76e-1)" "unprognostic (2.90e-2)" "unprognostic (3.25e-3)" "unprognostic (8.77e-2)" "prognostic favorable (9.08e-4)" "unprognostic (8.33e-2)" "unprognostic (6.45e-3)" "unprognostic (5.99e-2)" "unprognostic (4.89e-2)" "unprognostic (9.57e-2)" "unprognostic (4.38e-1)" "prognostic unfavorable (4.53e-4)" "unprognostic (2.52e-1)" 3.9 5.8 19.9 3.7 21.6 12.2 3.7 17.5 20.9 3.9 8.1 7.8 7.8 5.3 3.6 5.6 4.7 3.4 6.9 21.0 16.7 5.0 5.8 4.0 3.6 17.2 19.0 4.5 8.0 5.6 7.9 3.5 16.7 5.8 6.3 6.5 5.9 3.9 13.1 5.0 7.5 3.1 17.0 11.4 5.7 14.3 21.1 3.8 8.0 7.8 3.6 4.1 3.7 21.5 7.8 9.4 6.3 5.7 7.0 5.0 10.3 4.9 7.2 16.7 7.0 29.7 6.1 5.9 10.1 4.9 8.6 14.1 4.7 8.1 8.8 8.3 4.5 3.1 5.6 19.5 6.6 8.5 12.2 5.0 9.6 8.6 5.4 5.5 3.6 8.2 10.8 6.6 4.0 16.5 8.7 21.5 9.5 10.5 11.3 6.5 6.8 6.2 5.4 6.1 6.0 6.4 9.8 29.6 7.8 4.9 7.2 7.3 5.1 11.9 9.8 9.9 7.0 16.2 13.4 6.3 9.3 4.4 5.4 0.1 1.5 1.4 1.4 1.1 1.3 1.3 1.3 1.7 1.3 2.1 1.6 1.9 2.5 1.5 0.5 0.6 1.5 1.0 19.9 21.6 17.5 20.9 21.0 16.7 17.2 19.0 16.7 17.0 21.1 21.5 5.4 9.6 2.2 2.9 7.8 7.4 6.6 4.3 12.5 7.4 11.9 8.6 4.9 10.0 2.8 0.0 8.4 11.0 8.3 34.7 3.9 6.0 45.2 11.4 4.7 6.3 26.4 1.7 6.8 8.0 13.4 5.4 9.7 9.0 4.5 5.4 10.4 7.1 4.8 6.7 5.0 22.2 2.0 4.4 5.4 62.5 5.0 3.6 5.4 1.9 7.0 5.4 4.1 2.0 8.5 8.3 16.1 5.7 6.4 7.4 20.7 4.8 6.7 7.6 6.6 5.8 6.6 41.3 16.9 7.8 7.2 30.1 6.8 10.3 18.4 8.5 SPATA2L "C16orf76, MGC26885, tamo" ENSG00000158792 "Spermatogenesis associated 2 like" Q8IUW3 16 89696357-89701705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041182, HPA042453" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" Cytosol "HPA041182: AB_2677352, HPA042453: AB_2678005" "unprognostic (1.22e-1)" "unprognostic (9.04e-2)" "unprognostic (5.23e-2)" "unprognostic (9.13e-3)" "unprognostic (2.21e-1)" "unprognostic (6.62e-2)" "unprognostic (2.72e-2)" "unprognostic (2.13e-1)" "unprognostic (4.86e-2)" "unprognostic (9.25e-2)" "unprognostic (1.40e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-3)" "unprognostic (8.86e-2)" "unprognostic (4.19e-2)" "unprognostic (5.84e-2)" "unprognostic (2.55e-1)" 6.7 5.1 5.7 2.3 6.6 5.0 4.9 4.8 8.7 3.9 5.2 6.2 5.9 6.1 0.7 5.8 6.2 2.2 4.9 8.0 4.9 10.3 13.6 7.1 1.5 4.9 3.8 5.4 14.2 2.2 16.7 1.8 3.1 5.9 0.8 0.6 5.7 1.3 1.3 7.7 7.1 1.4 2.6 6.0 6.9 4.9 4.2 1.7 7.0 0.3 0.8 3.8 3.5 6.3 7.4 5.8 2.0 9.6 1.5 1.6 10.7 4.9 2.3 2.3 1.5 11.1 6.2 2.5 6.6 1.6 3.1 12.5 1.8 2.8 0.5 2.5 19.9 1.7 2.2 15.3 5.1 1.3 5.0 1.6 3.5 3.6 1.1 2.6 2.6 2.9 7.7 1.7 1.6 34.0 4.3 8.0 5.4 7.6 7.5 9.4 1.0 7.4 3.4 2.6 11.0 7.0 5.3 5.4 6.5 0.9 14.0 5.7 6.7 2.3 8.5 0.4 2.3 4.2 2.8 2.3 6.9 4.1 4.4 2.8 4.0 5.3 5.5 6.5 3.9 3.7 3.9 4.2 4.4 4.1 3.5 3.9 13.7 2.1 4.9 4.6 3.7 4.1 5.7 6.6 4.8 8.7 8.0 4.9 4.9 3.8 3.1 2.6 4.2 6.3 5.9 3.2 0.5 2.3 10.8 15.7 18.7 7.7 5.2 9.5 11.0 6.6 0.4 7.2 3.1 11.0 0.0 8.7 18.4 27.8 1.9 13.7 7.4 7.6 3.2 6.3 23.8 0.0 13.6 13.8 5.7 6.4 9.2 9.3 4.5 2.1 6.1 5.7 7.4 3.3 7.1 7.6 14.2 6.1 13.2 1.5 2.8 9.1 8.8 2.8 4.3 6.6 8.2 2.5 1.3 12.7 21.8 2.2 8.6 12.7 32.3 10.3 1.5 8.0 0.0 9.3 7.0 2.7 2.5 2.6 19.9 24.9 10.5 4.7 9.3 11.7 SPATS2L "DNAPTP6, SGNP" ENSG00000196141 "Spermatogenesis associated serine rich 2 like" Q9NUQ6 2 200305881-200482264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 478.4;Paneth cells: 467.4;Proximal tubular cells: 568.2;Skeletal myocytes: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.0" "Group enriched" "Detected in all" 5 "dendritic cells: 16.8;granulocytes: 48.0;T-cells: 31.6" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 475.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055427, HPA066310" Uncertain Enhanced Nucleoli,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Cytosol" "HPA055427: AB_2682813, HPA066310: AB_2685655" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (9.35e-2)" "unprognostic (1.78e-2)" "unprognostic (4.39e-3)" "unprognostic (3.58e-2)" "unprognostic (2.17e-3)" "unprognostic (3.44e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (3.95e-1)" "unprognostic (7.84e-3)" "unprognostic (3.71e-2)" "unprognostic (5.67e-2)" "unprognostic (6.01e-2)" "unprognostic (2.99e-1)" 47.1 27.0 36.9 37.2 38.4 10.4 31.7 35.2 48.6 77.5 44.2 85.5 82.1 37.5 26.6 65.3 81.6 114.8 117.3 41.4 41.0 70.0 110.3 47.6 24.1 42.1 45.0 66.0 60.6 41.9 40.4 68.8 44.0 50.7 83.2 16.5 166.1 67.8 70.6 33.6 82.8 51.3 43.6 39.1 101.4 28.9 39.9 40.8 42.9 36.3 22.9 81.2 45.7 46.7 174.8 94.6 113.0 13.8 74.0 96.4 43.4 299.6 100.1 193.2 143.8 262.6 190.0 1.0 69.1 197.4 108.5 167.5 35.2 186.9 130.4 109.5 47.2 1.4 80.0 315.2 138.8 28.9 12.3 121.4 182.5 134.3 128.3 138.0 75.4 21.6 41.1 119.0 280.0 55.4 4.4 8.3 28.2 303.4 226.7 0.6 388.2 11.1 475.5 134.2 3.1 31.9 77.0 45.5 127.0 165.3 23.9 39.5 120.9 131.3 129.3 41.4 170.9 34.9 36.3 2.2 104.1 14.1 179.5 48.0 5.2 7.6 5.8 5.9 14.0 2.8 6.3 6.0 16.8 3.3 2.6 3.1 4.2 6.8 4.7 12.8 31.6 2.8 36.9 38.4 35.2 48.6 41.4 41.0 42.1 45.0 44.0 43.6 39.9 46.7 83.4 86.6 26.2 104.5 11.2 91.1 262.5 123.6 67.7 21.4 63.2 51.4 127.8 403.2 70.3 172.9 12.5 19.4 9.5 478.4 111.6 157.7 75.9 129.8 59.4 64.2 55.1 15.1 116.4 147.0 38.2 101.8 151.9 56.9 56.5 51.4 94.2 230.0 82.5 60.6 202.9 246.6 54.9 139.6 98.1 22.4 165.6 56.1 128.1 68.4 18.0 8.7 2.1 79.9 106.5 210.8 467.4 142.1 9.4 284.9 153.2 568.2 167.1 56.4 78.9 470.9 89.3 38.0 82.6 68.4 77.9 9.9 28.2 6.6 78.4 198.8 SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765709 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA036062: AB_10611670, HPA067304: AB_2685820" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" 41.1 34.7 8.3 57.6 10.9 54.5 32.0 11.1 8.5 36.6 48.6 93.4 79.6 27.9 21.5 26.5 26.8 39.4 37.1 6.8 12.3 57.9 107.0 43.4 40.2 15.3 12.8 13.6 63.7 158.5 13.0 54.1 12.5 29.5 82.8 12.5 44.5 32.6 109.3 25.2 67.6 41.0 11.2 37.3 41.7 18.5 12.1 39.5 35.2 81.8 41.7 51.7 20.9 14.5 57.3 96.9 37.0 49.2 142.3 84.3 58.2 89.1 149.1 80.5 114.1 113.1 64.3 35.1 65.0 176.3 120.7 83.5 45.2 54.3 89.5 72.2 27.5 67.0 61.5 58.9 117.4 42.0 104.5 73.9 98.3 66.8 106.7 59.4 80.2 37.7 51.3 134.2 107.6 131.5 20.1 16.2 15.8 90.8 22.0 24.2 57.3 77.6 109.7 130.4 29.7 33.4 54.0 102.7 63.4 74.0 73.2 81.6 98.9 128.7 51.7 83.7 106.7 54.0 100.2 38.8 58.1 69.4 90.3 48.7 52.3 48.9 27.9 48.6 17.4 18.3 22.3 25.5 37.4 19.2 12.4 20.5 37.7 23.5 56.6 33.1 30.4 50.2 8.3 10.9 11.1 8.5 6.8 12.3 15.3 12.8 12.5 11.2 12.1 14.5 66.2 48.1 35.9 20.5 51.9 43.1 79.1 76.3 37.5 14.8 36.4 21.3 77.5 52.9 44.3 68.0 20.9 136.5 72.7 215.5 23.5 87.1 18.8 107.2 56.6 59.6 38.4 30.3 32.0 167.1 88.3 74.3 52.0 57.3 45.7 20.5 46.8 124.1 85.9 8.4 31.4 86.5 36.7 68.7 55.7 7.0 44.7 83.0 32.0 23.4 134.5 27.5 64.9 25.6 26.2 131.9 127.3 36.5 49.9 92.2 143.0 46.8 41.8 17.2 26.3 88.0 51.6 31.7 15.3 39.3 38.8 204.5 60.6 30.8 76.0 94.1 SPPL2B "IMP4, KIAA1532, PSL1" ENSG00000005206 "Signal peptide peptidase like 2B" Q8TCT7 19 2328615-2355095 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 109.1;Late spermatids: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005592, HPA039292" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Centrosome "CAB005592: AB_325074, HPA039292: AB_2676429" "unprognostic (4.16e-2)" "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "prognostic favorable (5.00e-5)" "unprognostic (2.34e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-1)" "unprognostic (7.93e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-3)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.26e-2)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (3.40e-2)" 23.1 23.2 13.7 16.7 13.6 29.1 27.4 15.5 18.6 28.4 17.4 43.4 41.6 26.4 4.4 22.5 34.0 10.7 21.6 11.8 12.1 35.9 33.0 22.2 20.7 19.2 15.6 27.2 50.7 11.0 63.8 10.4 15.5 32.5 9.2 7.1 27.2 9.8 25.3 28.9 52.6 5.9 13.2 39.1 33.9 63.5 15.1 12.0 40.5 3.1 9.9 21.9 20.9 16.4 16.6 25.9 10.9 19.5 8.8 8.9 27.8 21.1 6.1 7.6 8.1 18.2 18.4 15.7 19.4 9.9 7.1 21.7 3.6 7.3 2.3 18.4 16.0 10.4 44.7 24.9 16.5 18.6 13.1 13.1 8.2 7.2 5.2 11.9 10.7 32.2 17.3 39.0 4.7 18.4 20.2 23.6 20.4 14.7 10.5 33.4 5.8 43.9 8.3 41.0 19.4 18.3 21.2 12.8 16.7 7.1 21.3 30.8 24.3 13.8 9.7 35.3 16.9 51.0 20.1 16.7 17.3 21.4 24.5 11.5 7.7 7.4 6.2 7.7 4.4 8.2 5.6 6.0 9.4 12.5 6.9 7.7 3.3 6.4 5.4 17.0 6.0 6.4 13.7 13.6 15.5 18.6 11.8 12.1 19.2 15.6 15.5 13.2 15.1 16.4 23.6 3.2 17.2 57.1 30.8 0.0 6.5 0.0 8.0 26.1 21.6 21.5 6.0 20.0 5.0 25.8 47.9 50.6 18.8 79.5 1.9 16.6 51.4 39.3 22.2 14.4 40.7 14.5 25.3 11.5 20.8 14.2 109.1 25.5 7.0 39.9 13.2 15.1 11.8 32.0 30.3 63.2 0.0 9.4 0.0 107.7 14.9 10.8 0.0 9.4 8.0 13.2 19.6 39.7 35.2 10.4 49.9 15.8 11.5 7.3 57.8 7.9 10.9 39.4 0.0 15.0 11.7 57.0 13.5 10.8 0.0 42.8 11.0 36.4 49.8 6.0 SREK1IP1 "FLJ36754, P18SRP, SFRS12IP1" ENSG00000153006 "SREK1 interacting protein 1" Q8N9Q2 5 64718148-64768691 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 300.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045677, HPA062853" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA045677: AB_10964635, HPA062853: AB_2684881" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.17e-2)" "unprognostic (1.06e-1)" "unprognostic (1.51e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (8.60e-3)" "unprognostic (8.67e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.67e-1)" "unprognostic (8.39e-2)" "unprognostic (3.85e-2)" "unprognostic (1.99e-1)" 6.2 5.5 5.1 4.2 5.3 4.6 6.4 6.0 7.2 5.0 5.3 4.9 4.1 5.0 5.6 6.9 4.6 4.3 4.0 5.0 5.4 5.7 5.8 5.6 5.7 5.4 5.2 6.6 4.3 5.8 2.8 8.6 5.6 5.6 4.8 6.4 5.1 5.3 3.6 9.0 4.4 5.5 5.3 5.5 5.2 3.2 5.3 6.9 5.9 4.7 6.0 5.3 4.3 5.8 8.3 4.2 10.5 7.9 9.2 15.1 6.2 12.3 9.9 8.3 11.0 7.8 8.9 8.6 12.4 9.9 7.9 5.3 9.6 18.7 14.5 10.3 11.6 9.4 7.6 7.0 9.5 10.2 9.1 9.9 17.3 11.5 14.8 8.8 12.4 10.6 8.4 5.2 9.9 3.0 18.2 10.3 5.4 2.2 5.6 8.6 8.5 13.8 14.3 6.6 4.5 6.7 7.8 5.5 12.1 7.3 7.0 19.5 12.5 6.0 3.6 7.3 13.0 7.5 13.8 7.7 11.5 15.7 8.3 2.0 1.6 0.7 1.8 1.2 1.8 1.6 1.7 1.7 1.4 1.5 1.7 1.7 0.6 1.5 0.8 3.3 1.6 0.9 5.1 5.3 6.0 7.2 5.0 5.4 5.4 5.2 5.6 5.3 5.3 5.8 69.3 48.1 44.1 20.2 43.8 81.8 62.5 117.8 43.3 51.8 49.0 59.2 31.2 75.8 63.2 86.5 31.3 72.6 54.8 87.3 90.1 72.2 300.6 69.3 66.0 63.1 61.0 79.8 30.8 75.2 84.6 55.8 35.2 86.6 53.8 33.9 91.1 100.3 64.5 97.6 23.4 71.4 89.5 79.7 62.4 179.2 95.7 54.8 39.2 15.9 65.1 59.2 71.1 19.1 25.4 196.8 136.3 72.6 39.1 76.2 66.8 114.8 58.4 43.5 65.7 57.7 56.9 44.3 46.2 47.0 104.0 48.7 50.4 30.5 54.2 83.2 SRI ENSG00000075142 Sorcin P30626 7 88205115-88226993 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 566.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1172.0;Extravillous trophoblasts: 1475.3;Paneth cells: 1606.5;Proximal enterocytes: 1342.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019004, HPA073666" Enhanced Approved Nucleoplasm,Cytosol No No 1100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA019004: AB_2670006, HPA073666: AB_2686623" "unprognostic (1.86e-2)" "unprognostic (2.31e-3)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-3)" "unprognostic (1.24e-3)" "prognostic favorable (3.08e-4)" "unprognostic (9.87e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.36e-1)" "unprognostic (2.10e-2)" "unprognostic (1.29e-2)" "unprognostic (9.87e-2)" "unprognostic (8.44e-2)" "unprognostic (3.14e-3)" 98.7 89.5 139.1 95.9 147.8 85.2 95.9 148.0 177.1 87.0 115.0 566.0 178.0 70.4 122.4 68.3 147.8 52.3 81.3 135.9 159.7 104.6 42.3 84.2 69.3 146.6 150.6 83.2 75.8 56.7 75.3 64.5 158.3 69.9 447.2 50.3 74.4 64.6 37.6 49.2 252.2 94.2 155.5 60.3 66.3 38.9 147.3 54.6 70.5 53.0 78.2 136.8 81.3 165.7 181.7 59.5 188.5 193.8 295.0 247.0 89.3 106.5 177.5 121.5 143.3 56.2 414.0 198.9 108.3 168.0 296.6 182.8 237.6 244.5 160.2 155.9 92.2 103.4 177.6 0.1 173.8 139.0 108.5 250.5 221.2 127.0 185.1 218.2 365.4 123.7 87.8 175.8 170.4 106.3 211.7 94.5 159.4 261.2 119.3 86.1 256.8 110.9 229.2 179.0 131.5 151.5 323.0 188.0 154.7 179.7 88.0 61.4 218.1 223.4 185.6 201.5 192.9 159.6 79.2 222.4 220.7 130.5 387.8 620.5 151.3 580.6 169.8 217.3 202.4 173.0 185.9 194.9 201.0 151.9 137.7 158.5 93.3 224.3 262.2 161.1 210.4 216.7 139.1 147.8 148.0 177.1 135.9 159.7 146.6 150.6 158.3 155.5 147.3 165.7 258.8 86.6 123.7 63.6 84.4 95.1 389.6 494.2 75.1 34.9 117.2 129.5 107.1 35.8 402.0 156.3 12.5 166.0 104.7 1172.0 442.2 223.0 89.7 307.3 148.6 135.6 94.3 198.6 29.4 418.5 1475.3 175.7 80.0 172.7 135.6 131.3 106.7 40.5 147.6 47.1 22.9 471.7 276.7 79.5 117.9 34.0 172.1 103.2 104.9 15.9 172.5 195.6 113.3 40.2 34.9 380.9 1606.5 141.4 75.2 422.9 1342.4 182.2 660.4 25.9 111.7 111.9 183.9 80.8 106.3 86.9 108.3 197.4 117.9 126.8 536.9 488.1 SSNA1 "N14, NA14" ENSG00000176101 "SS nuclear autoantigen 1" O43805 9 137188660-137190370 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.70e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-2)" "prognostic favorable (8.94e-4)" "unprognostic (1.73e-1)" "unprognostic (4.44e-1)" "unprognostic (1.12e-3)" "unprognostic (2.15e-1)" "unprognostic (2.10e-2)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (9.07e-2)" "unprognostic (8.35e-2)" "unprognostic (2.68e-2)" "unprognostic (1.67e-2)" "unprognostic (7.72e-2)" "unprognostic (1.66e-1)" 46.3 48.2 64.5 41.7 67.8 61.6 45.3 66.5 89.0 38.8 62.4 52.7 42.1 39.5 18.4 77.6 38.8 24.4 81.5 64.2 66.4 60.8 66.5 38.7 54.6 67.0 66.8 30.3 75.9 30.2 27.9 29.1 66.8 48.6 19.2 10.1 61.5 27.8 78.7 62.0 45.9 26.0 65.4 52.2 68.3 124.8 67.4 48.5 37.4 41.9 34.9 48.8 43.8 72.3 79.1 167.4 54.9 86.6 52.0 45.8 56.8 71.8 63.9 96.9 53.5 82.6 108.2 77.0 89.3 60.8 84.2 128.2 65.6 99.2 14.7 140.7 44.9 62.7 128.8 89.0 70.8 104.6 64.5 46.2 86.2 64.5 56.3 45.7 87.8 112.5 69.4 141.9 66.7 225.2 138.8 107.0 86.5 167.7 73.6 91.6 75.2 223.0 83.1 67.5 96.7 54.8 56.9 156.0 82.3 21.3 167.2 122.3 63.8 94.3 53.5 141.6 98.2 34.9 140.3 76.7 103.6 103.3 79.0 117.4 96.7 161.1 99.6 143.8 90.3 118.0 91.6 100.9 90.6 117.9 84.0 85.1 85.0 107.7 136.9 146.1 140.6 93.7 64.5 67.8 66.5 89.0 64.2 66.4 67.0 66.8 66.8 65.4 67.4 72.3 72.4 41.7 44.2 7.5 83.7 63.7 58.0 78.3 63.2 39.1 96.1 115.6 49.9 94.4 59.4 62.5 16.7 150.7 109.9 200.5 113.5 144.6 76.3 80.3 54.4 64.8 77.7 97.4 14.2 233.1 170.5 51.5 65.2 75.0 57.2 57.8 49.6 84.0 156.3 40.4 13.6 131.0 71.2 78.0 82.8 56.6 60.3 82.6 119.2 7.5 186.1 86.7 107.1 8.0 39.7 207.0 166.2 50.8 83.4 88.6 210.2 194.3 52.7 40.3 32.9 27.8 67.1 320.6 114.2 113.5 84.0 111.1 89.9 67.0 130.2 72.7 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 489.4;Paneth cells: 327.2;Proximal enterocytes: 251.9;Undifferentiated cells: 216.9;Urothelial cells: 286.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.0" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.0" "Cell line enhanced" "Detected in many" "CACO-2: 224.2;CAPAN-2: 443.0;HaCaT: 311.4;OE19: 240.4;RPMI-8226: 301.2;SK-BR-3: 203.1;T-47d: 308.3;U-698: 218.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 4.3 3.9 0.8 26.7 1.2 4.3 17.7 1.8 2.9 18.6 1.2 124.7 130.7 5.7 21.8 104.5 37.1 32.6 0.9 0.9 1.1 43.2 6.3 18.5 11.9 1.8 1.7 0.6 59.2 36.5 19.1 15.1 3.1 23.1 60.1 0.0 58.7 23.6 0.3 50.2 144.8 5.4 1.1 9.1 64.9 1.0 10.0 10.5 28.6 0.0 20.9 34.8 42.5 2.7 167.2 0.2 0.0 0.6 0.0 0.0 86.4 0.0 0.0 0.0 0.0 224.2 443.0 163.6 16.7 0.0 0.1 311.4 0.0 99.3 0.0 0.1 0.2 0.1 0.1 0.9 0.0 22.0 0.8 0.0 49.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 128.5 0.3 1.1 1.7 240.4 0.9 0.2 0.0 301.2 28.8 134.2 17.8 0.4 1.5 203.1 0.4 1.6 308.3 32.0 0.1 0.4 2.7 0.7 0.7 0.2 0.3 218.5 0.3 50.4 0.5 0.0 3.6 3.4 0.0 2.2 0.1 5.0 0.0 0.0 6.2 3.6 0.0 0.0 0.5 0.0 0.3 25.0 0.0 1.2 0.8 1.2 1.8 2.9 0.9 1.1 1.8 1.7 3.1 1.1 10.0 2.7 0.2 32.1 28.6 0.0 18.2 40.9 51.5 45.2 26.2 0.0 36.5 21.5 1.2 77.2 61.6 62.5 0.0 45.6 26.1 489.4 3.9 115.8 37.8 43.9 5.7 1.7 123.4 0.8 1.0 91.8 14.6 3.2 112.1 79.6 11.4 0.2 0.4 2.1 58.1 0.0 0.4 201.0 148.5 22.7 13.2 13.9 1.8 28.0 7.2 0.0 13.6 0.0 1.0 0.0 0.1 153.4 327.2 0.7 5.9 108.7 251.9 10.0 76.4 0.0 6.6 0.0 4.9 0.2 0.3 61.3 43.9 39.7 2.9 0.0 216.9 286.8 ST6GALNAC6 "SIAT7F, ST6GALNACVI" ENSG00000160408 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" Q969X2 9 127885321-127905408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 258.8;Intestinal goblet cells: 100.6;Paneth cells: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "NK-cells: 23.7;T-cells: 25.6" "Cell line enhanced" "Detected in all" "ASC diff: 157.1" "Low region specificity" "Detected in all" HPA018890 Approved "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018890: AB_1857531" "unprognostic (2.27e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (5.71e-2)" "unprognostic (1.36e-1)" "unprognostic (4.84e-2)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.24e-3)" "unprognostic (3.31e-2)" "unprognostic (3.29e-1)" "unprognostic (1.10e-2)" "unprognostic (9.85e-2)" "unprognostic (3.46e-2)" "unprognostic (2.67e-2)" 95.8 37.4 155.5 21.4 156.0 17.7 68.7 129.5 177.8 48.7 120.2 75.5 9.5 48.6 50.0 35.0 67.2 28.4 61.3 165.6 130.9 50.1 63.5 66.7 27.5 133.4 137.2 83.0 52.8 32.4 26.0 22.0 128.3 40.2 126.4 16.0 28.3 41.5 46.0 37.4 35.2 38.0 128.3 64.1 43.9 17.6 140.6 14.9 32.5 40.2 23.1 56.6 42.6 134.6 12.0 9.2 18.9 36.9 157.1 91.9 7.4 29.7 69.6 43.7 35.9 16.3 10.0 13.8 13.4 68.1 28.4 21.9 25.6 23.7 19.0 50.9 14.0 13.4 19.0 16.7 48.1 3.3 18.9 94.9 27.5 34.0 15.1 61.6 40.9 11.9 12.2 14.6 54.9 9.9 8.4 19.3 9.1 12.3 17.5 24.6 27.0 14.3 32.2 2.4 13.1 21.3 21.4 8.8 7.6 12.3 9.3 29.0 26.7 27.6 16.3 30.5 15.8 18.4 9.8 21.5 24.5 4.1 8.7 3.3 1.2 0.1 25.3 1.9 18.5 5.3 16.5 18.8 1.8 3.9 10.0 13.7 0.6 23.7 5.0 2.1 25.6 12.4 155.5 156.0 129.5 177.8 165.6 130.9 133.4 137.2 128.3 128.3 140.6 134.6 1.3 3.2 4.3 13.1 10.5 23.2 17.2 15.7 9.1 22.0 0.9 0.6 8.7 8.6 9.5 0.0 6.2 4.3 11.7 258.8 0.0 0.3 2.5 0.8 1.7 20.6 38.5 26.1 11.5 0.4 7.7 26.6 3.6 1.4 7.0 0.2 46.8 28.5 11.6 25.2 10.7 100.6 18.3 10.0 35.6 9.4 66.5 4.1 24.9 8.4 3.2 58.7 46.4 5.5 3.8 0.3 178.3 60.9 8.9 20.5 0.3 0.0 16.1 8.5 85.5 41.2 31.9 1.4 4.8 10.3 26.9 3.6 17.7 0.5 84.7 18.6 STARD5 MGC10327 ENSG00000172345 "StAR related lipid transfer domain containing 5" Q9NSY2 15 81309053-81324183 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 28.0;Plasma cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 5.8;RPMI-8226: 6.2;U-266/70: 7.1;U-937: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040662 Approved Approved Vesicles,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Cytosol "HPA040662: AB_10959593" "unprognostic (5.35e-4)" "unprognostic (1.55e-1)" "unprognostic (2.58e-2)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (2.22e-4)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.08e-2)" "unprognostic (8.08e-2)" "unprognostic (6.81e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (4.84e-3)" "unprognostic (7.55e-3)" 1.0 0.6 0.6 6.0 0.8 4.3 0.7 3.4 1.3 7.2 1.9 2.8 2.2 4.6 5.0 3.4 1.8 1.3 0.8 0.6 0.7 0.7 5.1 1.1 7.7 0.9 1.0 1.2 0.6 0.6 0.4 1.6 1.2 3.6 3.7 0.4 1.6 2.1 0.6 7.9 4.2 1.8 0.9 6.2 2.1 0.7 0.7 0.5 0.8 0.3 1.5 2.5 5.5 1.4 0.3 0.0 0.0 0.9 2.3 2.3 0.1 0.3 0.3 0.8 1.2 0.1 0.1 4.8 0.0 1.5 0.2 4.0 1.1 1.0 0.6 0.1 0.4 1.8 0.3 0.4 0.5 2.8 5.8 2.0 2.0 0.3 0.6 1.5 0.1 1.9 0.6 1.3 0.5 0.1 0.5 4.0 0.3 0.2 0.0 0.1 0.7 6.2 0.3 1.4 0.3 0.1 0.1 0.5 0.6 0.3 0.6 0.6 0.2 1.3 0.6 1.3 0.1 7.1 1.5 1.8 0.9 6.8 0.4 5.0 1.8 2.3 3.0 2.4 2.5 1.0 2.7 3.2 2.6 0.7 3.9 3.9 1.3 2.6 2.3 1.4 3.6 3.7 0.6 0.8 3.4 1.3 0.6 0.7 0.9 1.0 1.2 0.9 0.7 1.4 3.8 0.0 1.1 0.0 11.4 13.3 12.0 28.0 10.8 1.8 2.7 4.2 0.3 0.0 4.9 0.0 6.2 2.5 4.2 22.1 3.9 1.3 15.2 2.5 14.4 2.5 11.4 2.5 2.2 1.4 4.0 8.5 15.8 2.3 10.2 1.0 3.6 25.4 5.2 1.7 2.0 24.3 2.0 7.9 10.9 1.5 5.0 8.0 1.8 1.9 0.7 1.2 2.1 0.0 0.4 1.8 14.4 9.8 31.5 3.3 23.9 0.7 4.0 0.9 0.0 3.8 2.8 0.9 0.7 19.6 16.3 4.9 4.2 6.3 19.9 9.6 STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol No No 1100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Cytosol" "HPA026435: AB_1854151, HPA026502: AB_1854152" "unprognostic (3.49e-2)" "unprognostic (2.39e-2)" "unprognostic (1.78e-1)" "unprognostic (3.44e-2)" "unprognostic (2.86e-1)" "unprognostic (3.25e-2)" "unprognostic (9.67e-3)" "prognostic unfavorable (6.23e-6)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.81e-4)" "unprognostic (9.62e-2)" "prognostic favorable (6.91e-5)" "unprognostic (3.10e-2)" "unprognostic (4.49e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-2)" 71.4 32.4 30.9 49.0 32.6 58.0 60.9 34.3 34.4 99.1 49.4 75.1 83.0 53.9 58.4 167.9 50.7 55.8 49.1 34.2 29.0 77.0 32.4 54.1 67.0 29.0 35.5 44.2 48.0 42.4 31.1 57.5 27.2 49.6 72.3 31.7 70.4 51.2 47.1 154.4 94.4 48.2 28.5 51.5 78.3 36.9 41.3 68.2 55.0 38.8 74.1 86.6 113.9 29.2 161.8 49.4 85.6 79.8 128.6 76.4 121.3 73.8 103.0 100.9 97.7 145.7 212.6 114.1 36.6 92.8 63.1 142.1 80.2 162.3 95.5 286.3 41.2 122.0 59.8 84.2 181.0 124.4 82.8 49.8 253.7 79.3 231.6 106.2 88.2 88.0 45.2 76.6 67.0 70.3 93.5 51.1 76.9 217.3 36.6 116.5 52.5 62.3 98.1 143.2 49.8 71.4 46.7 74.2 103.0 129.7 89.6 119.1 120.0 63.8 46.3 52.8 86.5 74.1 41.7 42.5 99.3 74.0 107.4 5.7 12.7 6.3 5.5 10.9 6.6 6.1 10.2 8.0 10.9 7.9 6.9 5.6 10.9 1.5 13.5 7.1 13.7 6.7 30.9 32.6 34.3 34.4 34.2 29.0 29.0 35.5 27.2 28.5 41.3 29.2 36.2 12.8 27.4 27.7 37.4 70.9 83.6 51.2 20.5 20.3 41.5 33.5 3.0 55.8 55.8 68.0 56.3 39.2 36.9 203.8 25.4 35.8 3.5 74.2 48.7 32.5 42.6 41.4 39.2 55.0 45.9 43.2 65.7 99.6 18.4 49.1 25.0 26.6 28.0 10.1 34.2 86.0 24.4 82.2 57.9 5.9 26.8 58.4 56.9 49.6 47.6 25.5 20.6 35.7 11.1 84.4 96.5 30.5 25.5 60.4 111.8 39.2 51.6 11.0 39.5 47.7 41.0 2.9 21.2 61.9 82.1 20.0 45.5 20.4 59.1 153.3 STX12 "STX13, STX14" ENSG00000117758 "Syntaxin 12" Q86Y82 1 27773219-27824443 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041038, HPA055300" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA041038: AB_10794261, HPA055300: AB_2682778" "unprognostic (3.47e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-1)" "unprognostic (8.16e-3)" "unprognostic (2.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.26e-2)" "unprognostic (3.52e-1)" "unprognostic (1.14e-2)" "unprognostic (2.78e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-1)" "unprognostic (1.91e-2)" "unprognostic (8.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" 64.2 30.1 38.1 26.6 39.0 10.8 37.0 40.8 45.6 28.8 25.4 30.7 36.3 30.9 62.9 39.2 23.9 39.8 20.9 37.3 41.7 35.2 29.1 50.0 25.6 42.0 45.3 22.1 30.3 46.5 26.6 33.3 43.6 30.7 32.5 43.2 26.9 32.1 21.4 27.0 32.8 35.9 42.2 30.5 65.5 13.4 38.4 17.3 94.7 27.1 22.2 39.1 23.4 44.6 23.2 10.9 28.8 19.0 53.9 65.0 14.8 47.9 70.3 43.1 48.5 13.5 29.5 25.2 49.6 64.6 18.5 19.0 19.2 23.9 42.9 22.2 22.8 14.4 12.0 13.7 42.2 16.1 29.0 61.3 28.7 60.6 34.5 35.3 70.3 14.3 19.1 24.6 47.7 8.5 13.7 12.3 12.1 34.3 15.3 8.7 23.1 15.5 38.1 37.5 32.3 17.6 22.4 19.3 35.2 23.3 13.1 14.0 76.2 21.9 12.5 50.0 16.6 14.5 11.2 14.3 35.1 24.1 31.2 24.6 35.7 13.7 6.1 39.4 10.6 13.6 7.3 9.7 25.2 10.8 8.1 6.8 16.5 9.2 40.6 12.4 7.9 17.4 38.1 39.0 40.8 45.6 37.3 41.7 42.0 45.3 43.6 42.2 38.4 44.6 93.0 54.5 36.3 25.1 43.6 109.4 97.2 30.7 51.2 46.2 42.0 25.7 18.9 30.0 40.8 57.0 31.3 30.0 28.3 82.8 37.2 51.9 2.0 34.7 33.1 71.1 41.3 17.7 70.9 58.4 33.5 53.2 108.6 49.4 22.8 26.7 47.8 20.4 50.6 26.9 65.7 29.5 14.2 91.4 77.7 4.2 36.1 62.3 53.4 56.2 41.3 67.9 36.0 34.7 59.1 68.4 58.6 47.4 33.9 74.9 51.3 69.7 27.4 51.2 39.5 45.7 57.5 20.0 20.1 69.9 99.2 78.0 31.6 54.0 29.9 99.9 SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming subunit beta" Q96I99 3 67360460-67654612 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 278.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 402.3;Proximal tubular cells: 354.4;Undifferentiated cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 300000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Plasma membrane" "HPA046705: AB_2679762, HPA051998: AB_2681687" "unprognostic (1.69e-1)" "unprognostic (2.31e-1)" "prognostic favorable (1.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (5.32e-2)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.88e-1)" "unprognostic (3.26e-2)" "unprognostic (4.61e-3)" "unprognostic (5.59e-2)" "prognostic favorable (2.79e-10)" "unprognostic (3.08e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" 66.7 44.9 16.1 36.7 17.9 18.6 48.7 17.1 19.6 42.1 22.4 169.7 136.6 32.6 32.2 50.5 39.1 48.4 85.5 14.2 17.6 147.3 278.0 34.0 39.3 19.0 17.3 39.0 47.8 34.6 10.2 28.1 19.5 49.3 146.1 7.3 46.8 42.3 154.0 26.1 132.2 40.0 17.7 44.8 110.6 10.4 18.1 24.7 49.3 130.6 35.5 39.3 24.0 18.8 43.8 37.4 36.3 44.6 59.7 102.5 44.2 51.3 74.4 58.9 65.4 41.7 95.1 55.7 16.3 72.5 38.8 22.0 28.5 70.8 75.9 23.8 19.5 50.5 31.2 65.5 76.8 67.2 33.9 77.3 60.3 46.2 105.2 73.0 63.6 41.8 39.1 49.5 129.9 30.6 25.5 21.2 34.1 199.2 23.0 17.6 56.1 83.8 100.0 66.9 7.1 24.5 81.5 92.7 68.8 24.3 71.6 42.5 55.9 58.2 38.2 64.5 61.8 33.4 52.2 39.0 85.5 51.6 70.0 17.3 36.3 13.0 30.8 44.3 37.6 45.5 44.6 39.5 24.6 42.5 68.4 53.1 1.6 68.0 37.4 9.8 45.4 48.5 16.1 17.9 17.1 19.6 14.2 17.6 19.0 17.3 19.5 17.7 18.1 18.8 40.2 35.3 50.8 66.6 48.5 37.1 44.7 38.9 21.1 2.9 54.1 29.1 172.0 84.4 51.7 80.9 8.4 55.4 31.7 223.5 244.6 85.1 3.2 49.6 43.4 40.1 58.2 17.2 6.2 80.9 44.9 47.5 90.7 46.8 30.4 31.4 45.0 402.3 56.5 5.0 5.3 212.1 40.7 68.6 49.2 5.4 41.3 36.3 42.7 90.9 35.5 29.2 36.0 72.4 60.0 59.2 164.0 47.4 30.3 41.2 222.2 354.4 58.7 4.5 32.9 41.6 50.5 1.6 6.3 55.6 49.3 38.0 48.6 78.5 306.6 50.9 SULT1B1 ST1B2 ENSG00000173597 "Sulfotransferase family 1B member 1" O43704 4 69721167-69787961 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.4;stomach 1: 44.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 298.2;Gastric mucus-secreting cells: 61.7;Paneth cells: 153.4;Proximal enterocytes: 234.3;Undifferentiated cells: 76.4" "Group enriched" "Detected in some" 11 "colorectal cancer: 7.6;liver cancer: 2.6;pancreatic cancer: 5.5;stomach cancer: 5.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 10.7;neutrophil: 32.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 32.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 110.9;OE19: 26.3;TIME: 36.2;U-2197: 31.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002107 Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA002107: AB_2666542" "unprognostic (9.58e-2)" "unprognostic (4.05e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "unprognostic (4.77e-2)" "unprognostic (5.14e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-1)" "unprognostic (1.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.06e-2)" "unprognostic (6.93e-2)" "unprognostic (5.46e-2)" 3.0 0.7 2.3 10.7 4.3 5.5 2.1 8.0 6.8 1.5 2.5 69.9 99.4 2.0 2.4 2.0 1.5 1.5 1.9 3.2 1.8 1.9 23.8 2.5 4.2 0.9 0.9 3.0 0.8 0.9 0.1 1.3 2.0 2.5 62.2 3.9 0.8 1.4 1.2 1.3 95.3 5.1 0.3 9.7 44.9 1.2 2.0 3.0 2.7 2.3 7.5 1.6 0.9 5.6 0.7 0.6 0.8 0.8 1.8 1.9 1.2 0.8 0.4 0.3 0.3 0.7 0.7 1.3 0.7 0.8 1.0 1.1 0.1 0.2 0.7 1.5 1.0 1.0 1.2 0.5 2.7 1.3 1.3 12.3 0.2 0.3 0.5 1.1 110.9 1.6 0.6 2.5 1.0 0.7 0.6 1.0 0.8 26.3 0.4 0.6 3.7 0.8 0.2 1.8 1.3 0.8 0.5 0.3 0.5 0.7 1.6 0.6 36.2 1.0 1.7 31.5 0.6 1.9 1.0 0.6 0.4 3.3 1.3 10.7 4.8 1.4 1.0 2.7 0.3 0.1 1.5 0.4 2.7 0.2 4.9 2.5 32.0 2.9 3.4 0.2 0.9 2.6 2.3 4.3 8.0 6.8 3.2 1.8 0.9 0.9 2.0 0.3 2.0 5.6 1.3 19.2 20.8 0.3 0.9 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 8.4 0.0 0.0 0.0 4.9 298.2 0.0 0.3 0.1 1.2 0.1 2.2 33.7 2.7 0.1 4.4 0.2 1.8 61.7 0.2 16.4 0.2 2.9 45.1 0.3 0.0 0.1 42.6 0.0 24.9 1.8 0.0 0.0 9.4 0.0 3.7 15.4 0.0 11.3 0.0 0.1 18.2 153.4 0.0 1.0 0.2 234.3 1.5 12.8 0.0 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.3 6.7 0.1 76.4 0.1 SURF6 "FLJ30322, RRP14" ENSG00000148296 "Surfeit 6" O75683 9 133328776-133336188 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 91.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023608, HPA074622" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA023608: AB_1857671, HPA074622: AB_2686703" "unprognostic (5.27e-3)" "unprognostic (8.67e-3)" "unprognostic (5.41e-3)" "unprognostic (3.69e-2)" "unprognostic (2.61e-1)" "unprognostic (3.20e-1)" "unprognostic (1.26e-3)" "unprognostic (3.60e-2)" "unprognostic (1.18e-1)" "unprognostic (9.37e-2)" "unprognostic (6.18e-3)" "unprognostic (9.32e-3)" "prognostic favorable (7.31e-5)" "unprognostic (1.50e-2)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (2.66e-1)" 10.4 11.7 8.1 4.1 7.8 4.9 10.3 8.7 7.5 12.4 5.9 13.6 6.2 11.9 2.6 12.5 11.2 2.5 10.5 7.2 7.5 11.7 12.3 8.5 5.5 7.7 7.8 13.1 11.2 3.9 8.1 3.3 7.8 11.5 3.4 3.3 9.7 4.0 17.9 13.2 12.1 2.7 7.5 11.4 9.9 7.9 7.9 4.6 10.6 3.9 3.7 12.2 11.1 8.1 5.6 8.7 6.5 9.8 4.0 3.7 10.8 8.8 5.1 7.7 4.8 13.8 9.2 16.2 6.7 4.9 5.6 16.7 8.4 9.3 2.8 10.8 9.6 11.2 10.5 8.3 7.2 19.1 9.3 5.3 8.0 8.0 7.4 6.8 4.0 15.6 25.1 8.4 6.8 14.7 15.5 15.7 19.1 22.7 15.6 16.1 9.1 16.7 6.7 5.3 13.7 11.6 8.6 13.7 7.8 3.9 12.2 10.6 8.4 17.3 9.3 8.9 12.0 6.2 9.6 21.0 6.5 12.9 10.4 3.3 3.0 1.4 4.3 2.9 4.5 4.6 3.9 3.9 3.3 5.1 5.2 4.4 0.8 3.2 2.7 6.0 3.6 2.5 8.1 7.8 8.7 7.5 7.2 7.5 7.7 7.8 7.8 7.5 7.9 8.1 25.7 44.8 27.3 4.6 20.9 23.7 15.7 11.0 24.5 26.5 33.4 32.3 30.0 28.6 24.5 22.0 6.2 32.2 20.3 36.8 21.5 29.2 1.3 21.1 42.2 23.6 33.6 14.1 4.3 19.6 25.2 21.2 18.8 25.1 25.3 25.4 16.4 35.2 21.2 21.9 4.8 40.3 6.1 14.7 10.2 4.1 27.7 13.7 7.2 5.6 18.6 15.2 29.9 5.0 4.1 29.0 33.3 27.8 14.4 24.8 50.6 26.1 13.2 19.6 0.0 15.8 20.3 19.2 23.6 26.3 27.6 19.0 18.1 91.1 57.7 13.3 SYMPK "SPK, SYM" ENSG00000125755 Symplekin Q92797 19 45815410-45863194 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.6;Late spermatids: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041756, HPA042449" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA041756: AB_10963544, HPA042449: AB_2678003" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (2.59e-1)" "unprognostic (1.59e-2)" "unprognostic (3.11e-2)" "unprognostic (2.33e-3)" "unprognostic (9.93e-2)" "unprognostic (9.78e-2)" "unprognostic (1.23e-1)" "unprognostic (9.16e-3)" "unprognostic (1.67e-2)" "unprognostic (1.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (2.58e-1)" "unprognostic (6.38e-2)" 18.0 17.3 15.5 29.3 17.0 27.4 18.0 12.5 19.8 24.1 11.9 22.5 22.2 25.3 20.1 19.7 23.5 18.0 17.5 14.9 14.1 19.1 21.4 20.6 34.8 18.9 15.6 23.6 19.1 20.7 32.6 25.0 17.1 23.8 14.1 15.7 24.7 16.4 38.5 25.3 22.8 16.1 11.4 28.5 22.9 41.0 16.6 30.0 24.0 18.9 22.8 20.7 19.9 22.7 57.7 101.0 40.4 29.9 39.0 46.8 67.7 44.5 32.0 45.8 51.0 45.8 51.1 101.6 30.2 51.0 25.7 46.2 55.1 49.9 40.0 79.4 62.2 58.7 68.9 47.5 43.7 64.9 65.6 36.1 29.2 49.3 55.4 31.2 47.6 52.6 79.3 64.4 39.4 54.8 61.0 70.3 34.0 50.0 23.9 64.6 46.4 62.6 31.8 102.7 46.0 57.7 55.1 35.5 36.7 40.3 48.4 89.4 53.5 37.1 58.5 28.8 66.9 84.1 173.1 81.5 42.4 42.8 61.8 1.7 3.0 1.5 2.0 2.5 1.9 2.9 1.8 3.2 2.8 4.8 1.5 1.4 3.4 2.7 5.0 5.8 1.4 2.1 15.5 17.0 12.5 19.8 14.9 14.1 18.9 15.6 17.1 11.4 16.6 22.7 14.7 0.0 7.7 34.9 30.2 20.9 18.7 15.6 18.2 21.6 17.4 15.4 7.0 22.8 12.0 25.8 35.5 35.5 20.9 32.7 54.8 21.6 141.6 24.9 29.9 23.4 36.3 26.5 24.6 17.5 34.5 17.5 41.8 27.7 12.7 35.1 26.0 31.8 18.2 21.9 27.1 38.7 10.2 27.0 25.6 146.4 19.3 24.4 14.2 19.7 47.3 11.3 32.0 29.1 28.4 20.4 25.5 21.1 19.8 21.5 30.8 14.9 15.6 27.4 19.7 17.4 20.4 35.3 34.1 14.4 21.3 57.3 21.2 21.9 38.6 20.6 TAX1BP3 TIP-1 ENSG00000213977 "Tax1 binding protein 3" O14907 17 3662895-3668679 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.9;Ductal cells: 351.0;Exocrine glandular cells: 385.9;Pancreatic endocrine cells: 505.8;Paneth cells: 362.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 164.3;granulocytes: 217.8;monocytes: 78.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046410, HPA063078" Approved Approved "Nucleoli fibrillar center,Vesicles,Actin filaments" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" "Vesicles, Actin filaments" "HPA046410: AB_2679656, HPA063078: AB_2684937" "unprognostic (6.15e-2)" "unprognostic (6.46e-3)" "unprognostic (3.37e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.80e-2)" "unprognostic (5.45e-3)" "unprognostic (5.19e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (5.12e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-3)" "unprognostic (1.92e-1)" 107.3 131.8 62.7 49.2 78.5 16.5 94.4 67.9 67.3 192.9 48.2 108.5 108.8 128.1 33.6 258.5 84.4 90.9 194.8 57.3 58.8 115.0 39.7 94.9 39.3 72.5 73.3 95.9 80.4 23.5 30.9 53.2 69.9 91.7 77.4 3.7 109.7 105.6 28.7 120.4 119.6 70.3 66.2 52.3 136.5 51.2 65.2 44.6 63.6 33.4 49.0 102.8 160.1 80.6 183.1 319.1 68.4 38.5 219.2 175.6 81.3 223.6 184.5 234.0 136.7 135.9 144.5 19.1 159.1 290.8 77.2 282.6 39.1 205.3 90.8 50.7 64.4 25.9 75.8 106.6 191.1 4.3 37.7 267.6 322.5 145.1 68.9 165.3 266.0 50.1 9.6 14.4 280.1 169.4 52.2 15.1 65.9 116.7 112.6 50.0 41.8 16.3 248.6 141.2 14.7 43.2 276.2 116.2 39.4 67.5 125.3 23.2 269.6 195.3 75.2 154.9 230.2 5.7 2.6 5.5 117.4 30.0 190.3 217.8 65.4 120.4 26.9 78.9 22.2 29.2 25.0 26.6 58.7 25.3 17.3 22.7 73.8 20.0 73.6 164.3 36.7 53.3 62.7 78.5 67.9 67.3 57.3 58.8 72.5 73.3 69.9 66.2 65.2 80.6 51.5 60.9 25.8 0.0 19.0 95.3 79.7 229.3 99.6 1.6 51.0 28.2 41.5 92.9 107.6 99.3 0.0 124.7 68.5 395.9 88.0 351.0 16.2 12.8 27.3 77.0 24.6 21.4 0.0 385.9 145.3 72.6 43.8 16.1 26.6 21.2 75.3 11.1 69.8 5.0 0.0 120.0 71.2 35.2 73.2 10.5 174.6 64.0 113.8 0.0 85.5 19.8 26.8 0.0 0.0 505.8 362.8 209.9 5.8 89.0 279.2 185.3 26.8 2.6 39.5 44.1 78.6 8.6 12.8 94.5 76.0 155.6 16.1 92.0 103.0 107.9 TCEA3 TFIIS.H ENSG00000204219 "Transcription elongation factor A3" O75764 1 23380909-23424748 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 513.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 214.8;Hepatocytes: 205.9;Intestinal goblet cells: 376.2;Proximal tubular cells: 260.9;Undifferentiated cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 8.4;naive CD4 T-cell: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 13.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 15.3;Hep G2: 55.1;OE19: 28.7;SiHa: 18.2;T-47d: 28.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044960, HPA055811" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA044960: AB_10964053, HPA055811: AB_2682932" "unprognostic (1.58e-1)" "unprognostic (1.75e-3)" "unprognostic (9.18e-2)" "unprognostic (3.82e-2)" "unprognostic (2.77e-3)" "prognostic favorable (2.56e-4)" "unprognostic (2.86e-2)" "unprognostic (4.70e-3)" "unprognostic (7.37e-3)" "unprognostic (2.85e-1)" "unprognostic (2.22e-2)" "unprognostic (3.27e-1)" "unprognostic (2.23e-1)" "unprognostic (4.01e-1)" "unprognostic (5.20e-2)" "unprognostic (3.15e-1)" "unprognostic (5.58e-2)" 17.5 95.6 4.7 4.6 4.3 0.6 19.6 4.1 4.7 35.7 7.8 87.1 15.8 17.0 7.3 40.5 28.3 11.6 71.6 4.0 4.4 64.9 160.7 20.4 2.4 6.0 4.9 81.9 229.4 16.3 14.9 3.9 5.4 59.9 39.8 3.2 100.3 14.5 513.3 53.4 35.2 9.2 5.2 10.6 75.9 4.7 4.1 1.8 41.2 173.1 4.5 36.2 38.7 5.1 0.0 0.1 0.5 0.5 2.5 15.3 9.0 6.4 4.1 3.2 1.9 4.1 0.5 0.2 0.7 7.9 1.0 9.1 0.5 0.1 2.8 0.0 0.1 0.0 6.9 55.1 1.9 0.8 0.0 10.1 2.8 2.9 0.0 7.1 0.4 0.1 0.0 0.0 1.1 1.5 0.4 6.1 0.0 28.7 1.8 0.1 0.0 0.2 0.0 0.1 0.5 0.1 18.2 0.8 0.8 1.5 28.4 2.8 0.4 0.0 0.2 0.7 0.0 0.5 5.3 0.0 0.5 0.5 0.6 0.0 0.2 0.0 0.4 0.7 0.4 0.0 8.4 1.1 2.9 0.0 13.6 6.1 0.0 0.2 0.2 0.9 0.8 2.3 4.7 4.3 4.1 4.7 4.0 4.4 6.0 4.9 5.4 5.2 4.1 5.1 10.5 125.0 109.5 4.2 1.9 27.4 53.4 30.9 30.7 2.3 46.3 42.4 109.8 100.1 57.2 42.3 2.1 3.3 1.9 158.0 199.6 37.7 6.1 7.7 6.6 13.4 55.9 5.7 2.8 97.9 33.9 45.2 69.3 20.8 9.5 214.8 8.2 205.9 1.5 25.2 4.5 376.2 6.1 7.6 65.4 17.9 17.1 8.4 24.9 3.7 3.2 6.8 3.1 2.0 1.3 25.5 143.0 15.4 0.5 38.8 154.3 260.9 29.4 1.4 19.7 90.1 24.0 0.7 2.6 61.1 54.8 2.2 8.4 52.0 223.5 73.9 TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 244.9" "Cell type enhanced" "Detected in many" "Astrocytes: 264.8;Distal enterocytes: 260.0;Extravillous trophoblasts: 231.4;Paneth cells: 211.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 244.9" "Group enriched" "Detected in many" 10 "intermediate monocyte: 28.9;non-classical monocyte: 86.6" "Lineage enriched" "Detected in many" 14 "monocytes: 86.6" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 5 "midbrain: 146.8;pons: 97.8;thalamus: 164.3" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" 28.1 9.4 47.4 8.6 6.3 7.6 25.0 0.2 12.1 18.9 1.0 22.9 20.4 25.1 6.7 9.9 18.1 9.4 11.3 4.3 46.9 9.9 22.4 13.9 5.4 5.1 98.0 22.9 12.4 11.1 9.6 17.7 1.7 12.3 21.3 4.6 14.5 13.1 8.4 17.2 19.3 16.4 1.6 22.2 23.3 7.6 244.9 5.8 12.9 6.9 3.7 13.8 14.3 3.2 15.0 37.8 40.7 39.6 20.8 13.7 48.5 10.3 20.0 7.1 8.5 24.9 45.3 0.1 11.3 19.4 9.6 10.5 14.0 17.6 9.1 1.7 13.1 10.4 25.2 23.6 22.0 4.2 3.7 24.4 6.3 11.0 18.2 29.7 12.0 8.8 11.0 0.7 8.2 28.0 6.7 2.5 29.2 16.6 21.6 19.0 29.8 6.9 15.2 20.4 0.8 12.4 15.7 15.4 17.0 31.5 10.0 2.2 27.9 6.8 18.7 16.9 21.3 2.6 0.3 0.4 6.5 8.7 14.9 0.4 4.5 0.4 1.5 28.9 0.9 0.0 0.4 1.2 4.1 0.0 0.4 0.6 6.0 0.0 86.6 0.2 0.0 3.5 47.4 6.3 0.2 12.1 4.3 46.9 5.1 98.0 1.7 1.6 244.9 3.2 62.0 22.4 26.5 264.8 3.3 42.6 27.3 35.8 64.9 2.8 53.0 54.9 13.6 52.9 35.5 40.5 6.2 44.2 9.1 260.0 11.7 39.3 8.8 40.1 140.6 46.1 19.8 4.8 35.1 43.6 231.4 90.8 90.2 64.2 0.0 37.6 52.8 74.2 17.5 5.0 16.6 87.7 16.2 99.9 20.6 5.0 59.0 54.6 32.0 107.7 22.4 34.4 5.2 192.5 34.9 59.0 211.1 48.5 6.0 38.4 75.3 16.2 26.8 6.1 92.1 37.3 51.3 9.4 28.9 61.1 39.8 28.5 6.7 13.1 73.9 49.0 TELO2 "hCLK2, KIAA0683, TEL2" ENSG00000100726 "Telomere maintenance 2" Q9Y4R8 16 1493344-1510457 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041348, HPA041473" Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Cytosol" "HPA041348: AB_10794514, HPA041473: AB_10795593" "unprognostic (1.27e-1)" "unprognostic (2.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-2)" "unprognostic (2.94e-2)" "unprognostic (5.99e-3)" "unprognostic (1.47e-3)" "unprognostic (2.21e-1)" "unprognostic (6.75e-2)" "unprognostic (3.15e-3)" 12.3 13.2 7.3 7.6 7.2 11.3 13.4 8.8 11.0 15.2 5.7 12.6 8.9 14.1 1.1 14.4 15.1 3.7 13.2 6.9 6.4 13.6 14.8 11.6 8.1 10.2 7.6 14.4 12.2 4.3 12.5 4.8 7.6 15.8 1.4 1.8 11.4 4.8 17.0 14.4 14.4 2.4 6.4 18.6 11.9 10.0 7.6 5.8 13.2 4.9 3.1 13.6 13.9 8.3 19.7 28.8 8.8 16.8 3.4 3.6 33.9 30.5 5.7 14.4 10.4 37.0 18.3 28.8 25.8 4.9 7.1 20.5 6.3 11.6 2.7 16.9 55.1 16.5 36.7 21.8 5.7 21.0 23.9 7.0 4.3 13.4 2.8 4.9 8.6 24.6 43.2 10.1 5.8 66.3 24.9 56.1 28.2 6.9 23.9 73.5 12.3 29.4 5.4 18.3 36.8 20.6 26.5 24.8 9.8 3.3 23.2 25.3 13.8 31.2 21.7 30.5 25.8 18.2 12.6 53.3 9.9 29.3 26.7 0.0 5.7 2.9 4.1 7.2 3.9 4.1 2.9 3.4 6.9 6.0 3.1 2.5 0.5 3.4 10.7 4.3 2.7 4.7 7.3 7.2 8.8 11.0 6.9 6.4 10.2 7.6 7.6 6.4 7.6 8.3 15.8 0.0 2.7 18.9 15.2 6.9 7.8 10.4 10.2 13.7 12.7 9.8 1.6 11.5 6.3 9.2 12.5 25.5 9.1 19.4 5.9 8.2 2.0 8.4 11.0 9.6 2.4 10.8 5.3 7.2 20.2 11.4 15.8 9.2 2.5 21.2 8.9 12.3 19.6 18.5 6.4 17.2 8.2 11.8 7.0 1.9 7.5 8.6 8.8 10.3 13.3 17.3 8.2 8.5 7.0 6.9 5.5 14.7 8.7 8.8 13.7 6.3 5.1 20.1 13.1 9.9 11.4 9.8 8.2 10.3 6.5 22.0 9.6 19.0 23.5 5.1 TGOLN2 "TGN38, TGN46, TGN48, TGN51, TTGN2" ENSG00000152291 "Trans-golgi network protein 2" O43493 2 85318020-85328296 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011489, HPA012609, HPA012723" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA 12000000 "Cluster 14: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "CAB011489: AB_443302, HPA012609: AB_1857976, HPA012723: AB_1857975" "unprognostic (3.03e-2)" "unprognostic (1.82e-2)" "unprognostic (2.35e-1)" "unprognostic (4.39e-2)" "unprognostic (3.90e-2)" "unprognostic (2.66e-1)" "unprognostic (5.50e-3)" "unprognostic (2.49e-1)" "unprognostic (2.98e-1)" "unprognostic (1.52e-2)" "unprognostic (5.19e-2)" "unprognostic (2.72e-2)" "unprognostic (6.30e-2)" "unprognostic (2.83e-2)" "unprognostic (3.22e-2)" "unprognostic (2.04e-2)" "unprognostic (5.37e-2)" 70.0 67.5 37.5 82.6 42.1 129.9 58.3 38.5 44.0 63.5 32.2 85.8 110.6 62.0 60.9 41.1 65.1 75.7 63.5 39.6 45.3 120.8 136.5 86.8 73.9 45.5 43.4 61.3 56.0 67.1 26.9 76.6 44.9 66.9 102.3 31.8 59.8 62.5 34.7 40.1 111.9 74.0 40.4 83.2 74.8 37.1 45.1 65.2 91.3 46.2 66.1 61.4 41.0 50.0 46.5 116.4 51.8 68.6 124.0 129.0 120.7 144.1 172.2 98.5 78.5 100.6 142.2 60.6 108.3 207.1 132.9 76.4 37.8 71.9 161.8 96.5 36.7 87.2 41.3 113.3 67.1 173.0 189.5 96.2 45.2 125.5 76.1 152.1 144.4 49.5 50.9 94.1 147.1 43.9 54.0 86.3 46.0 109.3 47.5 55.4 193.1 45.6 104.8 73.2 47.4 40.5 127.2 95.5 83.6 61.7 50.7 77.0 155.7 205.5 73.9 158.6 173.5 58.7 81.9 58.1 152.3 131.1 137.3 62.6 78.0 68.5 32.4 73.3 25.0 25.0 23.8 22.4 41.5 24.4 24.3 23.6 96.3 25.1 103.5 15.9 20.9 75.6 37.5 42.1 38.5 44.0 39.6 45.3 45.5 43.4 44.9 40.4 45.1 50.0 104.4 102.5 96.4 22.5 89.7 38.2 57.1 72.5 43.9 53.3 89.2 56.4 64.3 150.2 84.2 180.3 39.6 59.4 116.9 216.1 9.8 92.7 6.0 86.3 89.5 91.7 89.5 39.5 29.5 93.2 80.9 87.5 64.7 105.7 158.8 70.5 86.7 245.0 113.0 208.6 37.9 99.0 52.9 187.1 85.3 7.8 49.4 145.6 60.5 33.7 126.9 47.8 95.8 25.1 50.6 101.6 121.8 69.2 74.0 62.8 211.2 82.8 111.4 36.5 65.7 85.0 65.8 36.1 37.1 32.6 34.9 44.6 91.1 61.9 100.3 70.8 TICAM1 "MGC35334, PRVTIRB, TICAM-1, TRIF" ENSG00000127666 "Toll like receptor adaptor molecule 1" Q8IUC6 19 4815932-4831712 "Disease related genes, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.9;Paneth cells: 146.3;Urothelial cells: 134.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042460, HPA055421" Approved Uncertain "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA042460: AB_10806240, HPA055421: " "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.81e-4)" "unprognostic (3.52e-2)" "unprognostic (2.88e-2)" "unprognostic (7.60e-3)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.86e-2)" "unprognostic (1.59e-1)" "unprognostic (6.16e-2)" "unprognostic (2.82e-1)" "unprognostic (4.43e-2)" "unprognostic (2.30e-2)" "unprognostic (5.02e-2)" "unprognostic (3.53e-2)" "unprognostic (6.48e-2)" 12.8 6.4 4.5 6.7 5.0 15.0 11.2 3.1 7.5 14.0 2.3 13.1 14.4 9.3 1.1 45.6 9.4 7.0 10.3 4.7 4.9 13.9 20.1 16.5 6.9 5.1 5.1 7.3 10.3 2.9 6.1 4.4 4.7 9.4 3.2 0.4 13.5 3.3 19.7 21.5 14.5 3.3 4.6 11.9 15.7 1.8 5.1 2.6 8.2 4.1 4.4 10.1 17.4 4.5 34.9 6.7 0.1 5.8 4.9 6.2 3.1 11.2 11.4 8.8 9.8 6.9 12.2 23.5 6.2 12.9 8.8 23.1 3.2 11.8 3.4 25.4 6.2 5.9 13.7 6.7 13.5 2.1 14.7 10.1 14.4 11.0 8.0 6.8 9.2 8.1 12.9 4.9 4.8 13.0 6.0 1.2 1.0 6.2 26.5 13.2 1.4 15.4 8.0 10.7 4.6 8.5 6.9 20.4 11.4 0.0 9.2 4.9 18.5 10.7 7.3 27.4 17.1 19.6 18.5 16.7 12.5 8.1 8.4 6.8 4.1 1.8 1.7 5.4 1.5 3.4 1.7 2.0 3.6 2.8 1.1 0.7 1.2 1.2 7.1 2.5 2.1 5.1 4.5 5.0 3.1 7.5 4.7 4.9 5.1 5.1 4.7 4.6 5.1 4.5 10.5 6.4 9.6 3.9 12.4 69.3 67.0 20.0 23.9 0.9 19.4 13.6 2.5 21.5 18.5 5.5 0.0 6.3 3.7 156.9 7.9 29.9 0.1 27.0 7.6 14.4 29.2 4.2 3.9 17.5 11.7 11.0 42.3 56.2 10.8 4.6 11.7 13.4 12.8 1.7 3.2 39.2 10.2 14.0 52.6 0.3 3.7 22.1 14.2 1.9 17.7 0.8 7.2 3.0 1.4 51.8 146.3 5.3 18.6 57.5 55.8 9.2 16.3 0.2 6.6 4.6 5.8 0.3 1.4 27.3 71.2 3.4 9.8 3.4 26.2 134.3 TJP3 ZO-3 ENSG00000105289 "Tight junction protein 3" O95049 19 3708362-3750813 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.0;stomach 1: 27.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 238.7;Early spermatids: 405.1;Paneth cells: 140.4;Proximal enterocytes: 130.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 1.2;MAIT T-cell: 3.9;memory CD4 T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD4 T-cell: 3.3;naive CD8 T-cell: 1.2;T-reg: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.9" "Cell line enhanced" "Detected in some" "BEWO: 44.0;CAPAN-2: 41.1;MCF7: 20.3;OE19: 37.4;SK-BR-3: 25.7;T-47d: 52.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB013244, HPA046863, HPA053337" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" "CAB013244: AB_2533257, HPA046863: AB_2679845, HPA053337: AB_2682118" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.83e-6)" "unprognostic (2.78e-1)" "prognostic favorable (9.52e-4)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-1)" "unprognostic (6.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.78e-1)" "prognostic favorable (9.36e-8)" "unprognostic (8.58e-3)" "unprognostic (5.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.62e-3)" 0.2 0.0 0.2 4.7 0.1 0.1 4.0 0.1 0.4 6.3 7.4 34.1 43.0 1.5 2.4 25.5 13.7 6.2 0.0 0.4 0.1 5.8 7.1 5.2 0.4 0.2 0.4 0.1 6.4 7.5 1.7 1.6 0.2 4.0 13.2 0.1 20.8 5.3 0.7 7.3 37.4 0.5 0.0 0.5 27.0 2.5 0.0 0.2 6.9 0.0 2.6 4.1 6.0 0.3 0.3 8.3 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.0 13.0 41.1 8.2 1.3 0.0 0.1 10.4 0.6 0.0 0.0 0.5 0.2 0.0 0.7 2.9 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.3 0.0 20.3 0.0 0.3 0.9 37.4 0.2 0.1 0.0 6.2 1.4 6.8 0.2 0.2 1.6 25.7 0.0 3.3 52.2 0.2 0.0 0.1 1.0 0.1 0.0 1.7 2.5 0.1 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.0 3.9 0.4 3.1 2.4 0.0 0.6 3.3 1.2 0.0 0.0 0.0 0.0 3.8 1.2 0.2 0.1 0.1 0.4 0.4 0.1 0.2 0.4 0.2 0.0 0.0 0.3 0.1 9.6 13.7 0.3 1.9 0.0 7.0 21.0 0.0 0.0 20.3 6.3 0.9 34.3 42.1 31.3 0.0 32.1 0.8 238.7 19.6 21.1 405.1 31.2 1.1 0.5 12.5 0.0 0.9 23.6 4.2 0.6 52.5 13.2 4.5 0.1 0.0 7.3 2.7 0.0 0.9 50.9 24.4 0.3 0.3 36.5 1.8 0.8 3.6 0.0 0.1 0.0 0.0 0.5 1.4 21.8 140.4 1.2 0.2 6.5 130.4 8.0 86.1 0.0 0.0 0.0 3.4 4.3 4.8 8.0 0.1 40.2 4.3 0.0 62.1 25.6 TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 281.2;Pancreatic endocrine cells: 294.3;Syncytiotrophoblasts: 282.1;Urothelial cells: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 573.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" 231.0 120.9 118.0 84.1 135.0 96.1 165.5 124.8 123.6 146.8 112.1 143.1 152.6 119.7 92.9 333.4 97.3 135.5 123.3 109.4 131.2 123.5 170.8 175.1 55.4 194.5 144.0 93.5 240.3 125.6 50.2 172.7 150.7 97.6 140.7 15.2 155.1 89.5 219.1 185.3 174.6 127.1 139.8 65.9 212.3 25.4 134.1 41.9 158.0 185.2 106.8 172.9 215.1 144.2 183.9 66.4 3.5 47.1 404.3 170.6 188.7 175.5 217.9 103.4 117.7 169.8 449.0 40.6 123.3 263.0 194.6 305.3 59.8 399.9 100.4 151.0 23.5 264.6 41.8 205.6 183.3 2.4 252.4 161.1 370.7 210.4 265.6 108.4 111.8 6.7 169.0 75.0 182.9 6.1 2.8 46.5 2.5 382.3 60.4 5.7 28.3 33.1 142.1 573.4 2.2 3.1 58.0 214.7 122.8 36.6 56.3 39.8 168.4 182.4 50.1 84.9 64.8 35.9 45.2 17.7 179.9 41.0 105.5 352.9 136.4 298.5 107.9 172.7 91.8 77.1 98.0 89.1 93.3 61.9 64.3 70.2 167.1 66.7 221.9 25.9 116.1 190.1 118.0 135.0 124.8 123.6 109.4 131.2 194.5 144.0 150.7 139.8 134.1 144.2 47.6 73.7 25.6 20.9 37.2 81.7 96.9 85.0 51.2 2.0 28.8 26.0 26.4 78.6 66.9 69.9 0.0 139.1 51.8 266.8 13.7 175.5 0.6 45.6 42.6 50.8 22.7 66.3 2.4 281.2 146.8 61.9 110.6 78.4 50.0 16.1 28.9 50.4 104.9 0.0 2.5 67.9 52.9 45.1 50.2 2.8 54.0 69.6 46.2 14.0 22.0 22.9 48.4 5.0 35.2 294.3 177.3 59.5 30.3 151.8 204.4 37.7 34.8 1.9 13.1 35.7 45.0 1.4 12.5 86.5 101.2 282.1 41.3 9.9 69.1 299.8 TMCC3 KIAA1145 ENSG00000057704 "Transmembrane and coiled-coil domain family 3" Q9ULS5 12 94567122-94650557 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.3" "Cell type enhanced" "Detected in many" "Adipocytes: 81.2;Distal enterocytes: 98.3;Microglial cells: 70.3;Oligodendrocytes: 119.8;Paneth cells: 70.1;Urothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 46.9;neutrophil: 69.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 69.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 31.3;Karpas-707: 41.9;U-266/84: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014272 Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA014272: AB_1858059" "unprognostic (1.03e-1)" "unprognostic (2.54e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (5.87e-2)" "unprognostic (1.17e-2)" "unprognostic (9.12e-2)" "unprognostic (3.45e-3)" "unprognostic (1.24e-1)" "unprognostic (7.73e-2)" "unprognostic (1.80e-3)" "unprognostic (9.11e-2)" "unprognostic (2.32e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" 11.7 4.5 13.6 9.4 25.8 10.0 9.6 23.1 16.5 11.6 3.9 22.5 14.9 7.7 3.1 6.1 5.7 5.3 2.3 13.2 19.6 8.1 4.1 5.3 4.4 26.9 25.9 4.7 3.2 4.6 3.4 17.8 26.7 8.3 16.4 0.9 2.8 5.4 18.4 6.1 21.0 7.9 20.8 12.2 7.3 2.0 24.8 4.0 13.3 7.0 6.3 7.5 4.8 36.3 7.8 0.4 1.9 0.0 0.7 2.7 13.6 0.0 0.0 0.5 1.9 0.0 1.7 0.2 0.1 0.0 6.8 19.1 10.7 12.9 2.6 3.5 2.6 5.1 0.8 0.0 0.5 0.0 10.2 1.7 1.7 7.2 10.1 11.3 31.3 0.0 0.2 41.9 1.0 0.4 0.0 0.4 1.0 2.7 6.5 0.0 0.6 5.1 2.0 16.4 0.2 0.8 0.2 8.0 0.4 8.8 0.0 0.4 19.0 0.0 0.2 0.1 3.4 19.4 30.1 0.3 3.9 1.6 1.7 16.4 4.3 46.9 3.3 6.0 0.3 5.4 1.2 1.9 2.5 3.1 0.0 2.2 69.7 3.3 7.8 2.8 0.0 3.1 13.6 25.8 23.1 16.5 13.2 19.6 26.9 25.9 26.7 20.8 24.8 36.3 81.2 0.0 2.7 2.9 5.7 20.6 32.7 3.2 9.6 4.4 2.1 1.3 2.0 4.3 3.2 7.3 0.0 16.0 16.3 98.3 0.0 1.9 5.8 24.5 3.6 31.9 12.0 0.0 0.6 3.8 3.2 4.8 10.2 39.8 0.0 17.1 31.8 0.6 4.1 0.0 15.0 13.0 0.0 15.0 9.2 8.3 1.8 20.3 3.6 70.3 19.0 0.1 11.3 11.6 119.8 12.9 70.1 1.2 7.8 16.8 48.1 8.9 3.0 0.3 6.6 19.7 6.1 0.0 2.2 30.4 16.2 7.1 7.7 2.5 8.2 83.3 TMCO1 "HP10122, TMCC4" ENSG00000143183 "Transmembrane and coiled-coil domains 1" Q9UM00 1 165724293-165827755 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Glaucoma, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054768, HPA078775" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA054768: AB_2682597, HPA078775: " "unprognostic (1.22e-2)" "unprognostic (3.28e-3)" "unprognostic (2.36e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (5.17e-7)" "prognostic unfavorable (3.21e-4)" "unprognostic (5.92e-2)" "unprognostic (4.16e-2)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.85e-1)" "unprognostic (1.94e-1)" "unprognostic (2.14e-2)" "unprognostic (9.80e-2)" 67.5 92.5 46.4 51.6 50.2 48.4 91.1 53.8 63.5 74.0 72.2 127.0 115.7 55.9 111.5 58.5 65.9 80.1 56.4 46.4 55.6 110.3 162.5 55.0 62.4 54.1 55.5 59.5 73.5 143.6 33.8 57.4 55.0 79.6 128.7 74.3 77.8 69.9 48.7 39.3 108.9 61.4 56.6 46.5 80.7 75.4 49.8 89.3 103.8 48.0 70.8 97.7 29.1 60.6 158.4 172.1 132.2 77.9 243.9 120.7 126.9 259.4 191.7 156.0 162.1 249.9 229.2 99.1 267.4 195.9 67.1 214.7 171.8 140.3 175.1 252.0 164.2 121.1 180.3 158.7 195.1 216.6 154.1 159.0 173.9 179.5 142.6 148.4 117.1 122.6 329.7 186.0 227.3 123.1 172.1 160.6 169.4 527.6 197.3 125.0 143.4 256.1 204.7 198.4 133.5 235.4 201.3 209.2 170.9 195.0 277.1 275.7 121.5 138.9 116.5 123.8 248.3 357.4 521.1 346.5 111.4 139.7 187.4 213.3 172.2 172.9 159.7 169.4 170.4 151.8 168.7 173.1 135.5 132.6 134.3 156.5 132.1 156.6 201.7 243.8 207.1 290.3 46.4 50.2 53.8 63.5 46.4 55.6 54.1 55.5 55.0 56.6 49.8 60.6 124.0 96.1 70.7 23.8 95.6 84.8 89.8 264.5 75.1 79.1 142.9 135.9 62.6 224.4 181.1 213.3 68.8 136.1 138.9 371.5 43.0 202.3 82.2 131.4 147.9 92.7 88.6 75.5 20.7 191.7 148.4 113.1 64.2 154.7 76.5 71.9 106.7 326.0 140.9 75.7 24.9 137.0 227.9 106.4 76.0 151.6 123.6 92.7 99.6 16.9 78.9 236.7 152.4 25.6 23.3 227.0 215.7 129.4 153.5 73.6 290.0 151.5 175.2 75.9 124.9 67.7 101.7 232.1 87.7 89.4 92.9 111.4 109.2 117.6 143.6 94.5 TMCO4 DKFZp686C23231 ENSG00000162542 "Transmembrane and coiled-coil domains 4" Q5TGY1 1 19682240-19799945 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA014601, HPA014620" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA014601: AB_2204302, HPA014620: AB_2669051" "unprognostic (3.31e-3)" "unprognostic (8.94e-2)" "unprognostic (9.71e-2)" "prognostic favorable (3.71e-4)" "unprognostic (6.99e-3)" "unprognostic (5.46e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (9.21e-2)" "unprognostic (2.60e-2)" "unprognostic (2.30e-1)" "unprognostic (1.84e-1)" "unprognostic (2.71e-2)" "prognostic favorable (4.12e-11)" "unprognostic (1.67e-1)" "unprognostic (2.22e-1)" "unprognostic (9.81e-2)" "prognostic favorable (3.64e-4)" 7.9 8.9 1.4 5.3 2.4 4.7 9.5 1.3 1.4 8.7 6.5 7.9 17.3 9.8 21.0 8.4 10.3 6.4 4.8 1.6 1.7 9.2 5.4 6.1 6.9 1.9 2.2 7.2 10.8 34.6 3.6 3.1 1.7 13.2 6.1 0.3 17.0 10.6 2.3 5.7 9.6 5.6 1.7 9.5 11.7 1.7 2.0 3.7 11.5 2.4 5.0 9.4 7.9 1.5 9.3 5.6 0.0 0.3 7.5 5.2 6.2 6.8 20.9 13.1 7.3 4.6 42.5 16.2 9.9 19.7 5.8 6.9 1.7 6.8 2.7 13.8 1.7 6.1 6.6 2.3 6.1 0.0 8.1 5.4 7.6 4.4 2.5 4.8 6.3 0.3 1.2 10.7 5.8 7.9 0.0 3.6 0.6 12.6 7.9 3.1 17.5 10.0 11.2 7.2 0.0 0.7 9.0 12.3 13.9 0.9 10.6 10.4 4.0 10.0 4.6 7.2 4.7 1.2 0.6 4.6 11.4 13.8 6.5 0.1 3.8 2.1 4.7 6.7 4.7 4.2 5.0 5.0 7.4 4.9 3.7 3.2 0.3 4.2 4.1 0.2 3.9 3.6 1.4 2.4 1.3 1.4 1.6 1.7 1.9 2.2 1.7 1.7 2.0 1.5 5.8 12.8 11.0 8.8 9.9 2.8 9.6 6.3 4.6 0.2 17.0 15.4 8.0 2.8 12.0 11.0 0.0 9.3 6.0 12.3 9.8 13.2 0.3 10.6 8.1 5.2 6.0 6.5 2.4 16.9 18.6 7.7 15.8 16.5 3.8 7.7 5.3 5.1 9.1 0.0 5.0 15.9 12.2 7.1 3.3 0.5 6.2 6.7 10.6 11.2 9.5 3.0 5.2 3.0 0.4 11.0 7.5 5.7 6.9 11.4 4.5 7.9 18.8 0.5 0.0 6.1 7.7 0.3 2.1 7.9 2.6 7.3 8.2 5.7 14.2 7.9 TMEM120B ENSG00000188735 "Transmembrane protein 120B" A0PK00 12 121712752-121783001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 93.1;NK-cells: 76.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014066 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" Cytosol "HPA014066: AB_1845296" "unprognostic (8.80e-3)" "unprognostic (3.31e-2)" "unprognostic (1.95e-2)" "unprognostic (1.40e-2)" "unprognostic (3.10e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.66e-5)" "unprognostic (3.62e-1)" "unprognostic (3.29e-1)" "unprognostic (5.54e-2)" "unprognostic (2.10e-2)" "unprognostic (1.25e-1)" "unprognostic (5.86e-2)" "unprognostic (8.02e-3)" "unprognostic (2.31e-1)" "unprognostic (2.13e-3)" "unprognostic (4.72e-2)" 7.6 10.9 6.7 2.6 17.1 7.7 6.9 18.2 8.9 27.1 4.3 6.9 3.5 13.7 2.3 4.4 18.6 2.1 7.7 9.8 3.3 11.4 7.9 6.5 3.0 5.2 1.5 8.6 16.7 4.4 19.9 1.7 5.5 9.0 2.0 4.2 11.0 2.7 13.9 5.5 5.3 5.5 1.0 6.7 8.8 5.6 5.1 1.3 13.8 4.9 1.7 6.7 11.7 3.0 5.4 17.3 4.1 11.7 5.0 6.6 8.5 7.0 7.8 6.4 5.2 11.0 5.6 5.6 4.3 7.0 6.3 8.9 9.6 8.1 3.4 3.4 9.7 7.9 6.1 7.1 6.8 5.5 5.9 6.1 7.2 7.3 5.2 11.0 4.0 12.2 7.2 3.8 3.9 8.1 9.6 7.6 7.7 3.4 10.9 11.4 16.9 7.4 3.4 5.7 15.6 11.1 7.2 5.4 6.1 7.4 12.8 4.4 5.3 8.7 10.0 5.5 6.1 9.5 3.8 3.9 10.9 7.0 8.8 1.0 0.3 0.3 0.7 0.3 0.5 0.6 0.7 0.5 0.4 1.1 0.5 0.5 0.7 0.6 0.3 0.9 0.6 0.3 6.7 17.1 18.2 8.9 9.8 3.3 5.2 1.5 5.5 1.0 5.1 3.0 3.3 25.6 12.2 12.1 14.0 6.5 5.3 6.5 4.6 35.4 9.2 5.5 5.9 8.6 9.9 11.0 22.9 6.4 45.9 36.7 7.9 7.8 19.7 30.6 12.6 4.8 6.6 16.6 29.8 12.3 6.9 9.1 8.2 42.9 4.5 29.8 1.8 4.6 5.7 13.5 40.7 4.9 4.1 4.7 93.1 39.9 6.5 17.6 1.8 10.3 32.1 3.6 76.2 7.1 6.6 30.3 33.6 6.4 19.8 7.2 29.4 7.0 15.7 20.6 6.6 10.3 8.6 8.4 7.5 2.9 7.0 11.4 28.0 16.8 5.4 10.0 TMEM127 "FLJ20507, FLJ22257" ENSG00000135956 "Transmembrane protein 127" O75204 2 96248514-96265997 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.15e-3)" "unprognostic (2.67e-1)" "unprognostic (1.72e-2)" "unprognostic (6.51e-2)" "unprognostic (5.82e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (6.59e-4)" "unprognostic (6.73e-2)" "unprognostic (4.25e-1)" "unprognostic (1.06e-2)" "unprognostic (7.50e-2)" "unprognostic (2.17e-1)" "prognostic favorable (6.69e-5)" "unprognostic (3.59e-1)" "unprognostic (1.52e-1)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" 29.3 34.6 25.9 28.5 24.6 53.0 25.6 20.1 30.6 30.7 15.7 34.4 32.6 30.0 21.4 40.0 25.2 32.3 67.8 26.7 23.6 29.5 35.4 31.6 21.4 24.5 26.3 31.9 28.5 73.1 29.4 26.8 24.5 26.1 30.5 27.6 39.7 42.4 25.9 33.0 34.7 35.1 21.1 34.7 27.8 10.2 29.7 19.1 26.2 30.6 25.4 38.6 27.8 21.9 28.8 38.0 19.9 30.7 86.0 43.3 36.7 36.9 65.9 38.6 35.2 37.9 40.0 17.9 52.8 73.3 67.8 45.1 23.1 34.2 26.8 36.1 17.8 31.2 17.6 37.5 55.4 26.7 54.0 52.7 48.0 48.0 35.3 51.4 44.5 12.1 19.5 37.6 39.8 32.8 17.6 16.8 27.3 33.9 40.4 16.4 25.0 26.9 42.9 48.7 22.3 23.4 27.1 63.8 31.3 40.2 23.6 28.2 52.5 63.9 36.2 55.9 25.8 28.2 29.6 14.1 42.6 30.9 34.7 3.9 6.3 8.2 2.8 6.6 3.0 1.8 2.1 3.0 4.3 1.9 1.6 2.2 14.3 1.5 5.3 2.5 1.6 3.2 25.9 24.6 20.1 30.6 26.7 23.6 24.5 26.3 24.5 21.1 29.7 21.9 24.8 19.2 15.3 7.2 13.4 17.2 16.6 14.5 12.0 22.1 20.0 12.8 39.6 22.8 20.2 27.6 27.1 11.4 19.3 88.2 15.6 29.7 5.2 16.4 15.1 23.1 16.3 9.0 12.9 34.8 13.1 16.7 14.8 28.8 13.9 13.6 29.6 35.7 37.7 21.9 15.7 26.7 12.2 59.8 33.2 5.8 13.7 34.0 16.0 5.6 41.9 7.8 15.5 8.0 6.6 41.0 35.1 17.0 13.0 23.1 43.9 13.3 15.7 16.9 6.6 18.5 19.4 9.1 2.9 12.6 23.3 24.2 14.3 15.9 18.6 34.1 TMEM129 D4S2561E ENSG00000168936 "Transmembrane protein 129, E3 ubiquitin ligase" A0AVI4 4 1715952-1721358 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.07e-2)" "unprognostic (1.54e-1)" "unprognostic (2.12e-1)" "unprognostic (2.85e-1)" "unprognostic (4.04e-2)" "unprognostic (1.22e-3)" "unprognostic (7.35e-3)" "unprognostic (4.82e-2)" "unprognostic (2.27e-1)" "unprognostic (2.94e-2)" "unprognostic (2.51e-3)" "unprognostic (2.81e-1)" "prognostic favorable (9.64e-8)" "unprognostic (1.47e-1)" "unprognostic (6.49e-2)" "unprognostic (3.08e-1)" "unprognostic (2.36e-3)" 20.8 33.7 30.2 11.0 31.2 6.1 20.6 30.2 30.7 23.7 37.1 34.4 22.0 27.8 10.1 25.0 26.7 11.8 38.6 27.9 28.1 41.2 46.9 21.7 13.0 35.0 32.6 25.8 36.9 33.2 43.0 10.2 29.5 29.6 8.5 6.4 32.9 19.1 30.9 20.3 26.1 9.5 33.2 25.9 31.6 15.4 32.2 8.1 35.5 18.7 8.2 27.0 19.8 30.1 16.1 18.4 15.0 22.4 27.0 15.7 17.3 12.7 20.4 13.0 13.9 13.6 38.8 20.9 14.9 13.7 23.1 15.8 7.7 16.2 2.2 14.5 23.1 11.9 13.9 17.5 22.0 16.4 19.9 26.1 34.2 7.1 6.5 30.1 20.3 19.4 13.2 15.1 12.4 12.6 22.4 26.5 23.3 17.6 22.4 14.3 7.9 26.0 32.6 17.6 34.7 21.4 10.9 19.0 17.3 5.3 39.3 7.5 14.0 15.0 11.3 13.3 12.5 37.7 12.1 10.0 17.3 22.2 16.4 0.1 1.7 0.0 1.6 1.1 1.4 0.7 1.4 1.2 1.6 0.9 1.0 0.7 0.3 1.0 1.2 3.7 0.7 1.1 30.2 31.2 30.2 30.7 27.9 28.1 35.0 32.6 29.5 33.2 32.2 30.1 13.2 22.4 9.3 17.0 11.4 5.1 15.2 9.6 13.6 27.2 15.4 13.0 12.9 18.6 6.6 23.9 6.2 20.9 26.8 28.8 25.4 20.4 1.1 7.9 8.2 12.4 13.1 8.6 7.3 19.6 7.8 17.4 12.8 8.4 10.2 14.7 15.4 19.9 17.9 25.2 9.0 26.5 14.2 11.7 4.9 3.1 30.4 8.7 10.6 13.1 7.2 39.6 25.7 8.0 11.9 14.1 14.9 36.1 13.1 16.8 24.0 18.4 7.9 19.7 13.1 21.9 17.1 7.1 5.6 13.7 9.5 5.5 12.1 22.7 33.8 11.3 TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 580.8;Distal tubular cells: 626.1;Intestinal goblet cells: 547.5;Paneth cells: 682.0;Proximal enterocytes: 633.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 228.2;T-47d: 221.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Cell Junctions" "HPA014615: AB_2204756, HPA050244: AB_2681061" "unprognostic (2.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.53e-3)" "unprognostic (1.52e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.24e-1)" "unprognostic (8.45e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" 32.7 44.1 37.9 23.3 40.1 40.2 48.7 43.8 42.6 36.4 39.7 120.5 48.4 25.2 63.6 109.6 48.2 27.9 74.0 36.8 41.3 116.8 134.7 39.3 21.1 42.1 40.2 33.4 74.0 83.0 62.2 41.9 44.4 132.3 112.2 12.2 61.5 28.5 38.1 68.7 60.6 22.4 40.0 38.7 76.2 33.1 41.1 29.8 66.3 35.8 26.4 39.2 49.5 44.1 55.0 35.9 34.9 21.1 42.2 34.1 69.9 30.8 47.4 35.9 29.0 47.9 47.5 53.4 44.1 32.5 32.0 78.2 14.0 87.8 11.6 38.7 27.5 30.4 18.0 52.3 60.8 31.1 35.5 33.1 146.4 26.7 79.0 42.3 54.6 67.4 28.9 26.7 48.2 102.0 42.0 21.2 16.7 228.2 43.8 34.6 37.6 156.1 82.1 28.4 55.3 25.7 32.9 125.7 35.1 27.1 221.4 28.9 38.5 24.6 19.9 46.3 19.5 17.0 29.7 28.2 39.9 44.2 37.2 19.5 29.5 20.4 23.1 44.2 20.6 18.2 15.1 16.0 24.1 23.0 20.6 19.5 7.3 29.9 37.4 90.6 16.4 29.1 37.9 40.1 43.8 42.6 36.8 41.3 42.1 40.2 44.4 40.0 41.1 44.1 62.0 57.7 79.0 6.5 39.6 40.7 99.3 120.5 55.2 13.8 128.7 152.9 42.3 124.4 100.9 117.7 8.4 182.4 64.0 580.8 626.1 179.2 48.4 80.1 50.4 48.5 206.9 53.6 8.2 78.5 141.7 59.1 76.5 148.2 41.8 67.5 56.0 171.7 148.5 5.0 6.4 547.5 109.9 61.6 29.8 134.9 37.6 53.7 85.4 2.8 85.7 61.1 78.2 2.5 11.7 90.1 682.0 29.7 34.8 193.7 633.0 459.2 60.9 30.0 46.0 32.4 46.9 57.2 53.5 156.7 62.8 274.3 42.7 65.1 460.1 125.9 TMEM168 DKFZp564C012,FLJ13576 ENSG00000146802 "Transmembrane protein 168" Q9H0V1 7 112762377-112790423 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020389, HPA077143" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Cytosol "HPA020389: AB_1858101, HPA077143: " "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (2.55e-1)" "unprognostic (4.92e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-2)" "unprognostic (2.30e-3)" "prognostic favorable (4.07e-6)" "unprognostic (1.60e-3)" "unprognostic (8.73e-2)" "unprognostic (3.07e-3)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.47e-1)" "unprognostic (1.84e-1)" "unprognostic (4.89e-3)" "unprognostic (3.30e-2)" 12.9 10.6 6.0 12.5 7.6 6.7 15.6 7.5 7.1 11.6 9.5 22.4 13.7 13.2 17.9 14.1 10.7 12.2 13.9 5.8 6.8 12.8 8.4 12.1 11.3 8.1 6.6 12.1 6.7 28.6 8.3 14.4 8.2 16.3 24.6 20.2 20.6 13.4 9.4 26.7 14.8 15.3 7.8 12.3 12.6 10.2 6.7 13.5 17.7 9.4 11.2 10.9 12.9 10.1 16.0 13.2 12.2 10.9 20.4 41.5 17.2 17.3 16.2 6.4 5.6 17.0 16.4 16.9 11.4 17.2 14.6 16.8 12.5 15.1 16.5 26.8 12.9 14.7 16.8 9.7 13.7 16.4 17.9 20.3 38.6 7.3 10.9 6.0 18.9 13.6 19.9 15.0 23.3 25.2 14.2 10.3 9.9 16.7 10.2 9.5 6.1 24.9 16.0 29.9 9.2 18.2 23.3 30.6 14.0 14.9 17.5 14.4 27.0 30.5 15.5 14.5 22.6 25.4 23.1 18.9 19.7 14.7 40.0 21.2 14.9 11.6 12.1 12.6 14.4 10.9 12.9 11.8 16.0 13.2 18.6 13.0 8.4 13.5 13.2 11.1 13.0 9.5 6.0 7.6 7.5 7.1 5.8 6.8 8.1 6.6 8.2 7.8 6.7 10.1 17.4 12.8 22.3 43.1 18.6 31.1 19.1 12.0 27.3 31.5 16.4 14.4 18.1 10.0 18.9 33.1 27.1 35.5 14.3 16.9 0.0 5.9 2.9 9.2 22.1 17.3 20.5 14.1 29.9 9.1 8.9 17.6 18.3 11.8 12.0 19.2 18.5 12.6 8.9 16.8 32.6 34.8 16.2 13.5 9.3 1.9 18.3 10.9 24.9 41.2 10.8 16.3 15.5 70.9 71.5 6.1 17.0 14.7 10.2 21.6 15.5 6.0 7.1 29.6 6.6 19.4 16.7 18.1 13.3 24.8 26.0 14.2 13.8 21.1 30.5 14.5 TMEM170A "FLJ37611, TMEM170" ENSG00000166822 "Transmembrane protein 170A" Q8WVE7 16 75443054-75465497 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.49e-1)" "unprognostic (1.18e-1)" "unprognostic (2.95e-2)" "unprognostic (1.52e-3)" "unprognostic (1.08e-1)" "unprognostic (3.33e-2)" "unprognostic (1.02e-2)" "unprognostic (8.62e-2)" "unprognostic (7.97e-2)" "unprognostic (3.19e-2)" "unprognostic (1.53e-1)" "unprognostic (7.15e-2)" "prognostic favorable (2.36e-9)" "unprognostic (4.37e-2)" "unprognostic (3.41e-1)" "unprognostic (7.80e-2)" "unprognostic (1.53e-3)" 8.2 9.8 7.7 10.6 10.6 36.6 6.0 9.2 9.0 7.7 7.9 12.1 14.5 8.0 6.0 8.4 7.6 7.8 7.2 7.4 9.3 9.2 12.7 8.0 11.9 11.3 10.2 10.2 10.2 3.9 8.7 10.2 9.9 7.6 10.1 14.9 6.5 3.2 3.7 7.8 13.7 6.3 9.3 9.2 7.3 17.4 8.5 6.8 9.7 4.9 9.7 8.1 7.8 16.9 14.2 17.1 21.8 22.3 9.5 7.7 38.9 9.2 5.2 7.4 11.3 35.3 30.7 19.6 17.0 4.4 16.4 25.9 18.3 8.9 13.0 12.0 11.4 10.6 16.4 22.4 6.3 25.3 27.3 6.7 6.8 12.5 9.4 8.7 6.5 22.7 21.8 15.2 3.9 28.8 22.3 16.8 26.1 17.2 9.2 43.5 8.5 15.7 5.1 18.3 12.8 14.9 22.4 7.0 12.6 25.6 9.4 11.6 9.6 12.6 21.4 10.1 10.2 13.7 17.3 60.3 9.8 14.7 14.4 14.5 26.6 38.2 27.9 29.1 36.6 28.9 29.1 31.8 24.0 28.8 30.9 27.3 33.3 25.4 26.9 26.8 23.1 21.6 7.7 10.6 9.2 9.0 7.4 9.3 11.3 10.2 9.9 9.3 8.5 16.9 39.7 19.2 15.0 20.5 49.0 19.9 45.7 37.8 26.7 25.6 37.7 27.1 9.3 40.0 25.3 20.2 37.5 73.0 65.0 86.2 25.4 26.8 40.5 62.5 23.6 37.2 34.1 17.1 17.6 19.3 51.5 24.3 16.8 67.7 28.6 57.3 35.3 24.2 37.2 37.0 15.9 37.6 22.4 31.8 29.7 8.7 24.2 38.3 21.4 11.2 41.2 43.7 42.2 24.1 29.8 23.3 67.6 21.4 29.2 57.5 53.5 30.2 32.4 38.3 32.9 19.9 20.1 88.5 61.8 19.7 20.0 53.4 49.0 36.7 56.0 67.8 TMEM171 PRP2 ENSG00000157111 "Transmembrane protein 171" Q8WVE6 5 73120569-73131809 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 35.6;kidney: 10.8;lymphoid tissue: 14.3;stomach 1: 25.4;thyroid gland: 31.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 28.6;Distal enterocytes: 106.0;Gastric mucus-secreting cells: 29.6;Ionocytes: 40.7;Paneth cells: 63.4;Proximal enterocytes: 41.9;Undifferentiated cells: 51.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "MAIT T-cell: 24.1;memory CD8 T-cell: 8.2" "Lineage enriched" "Detected in single" 89 "T-cells: 24.1" "Cell line enhanced" "Detected in many" "BJ hTERT+: 35.0;LHCN-M2: 66.1;RPTEC TERT1: 51.5;WM-115: 177.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 3.7" HPA042308 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA042308: AB_10796901" "unprognostic (7.34e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (7.74e-3)" "unprognostic (2.81e-5)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.44e-3)" "unprognostic (1.77e-1)" "unprognostic (1.85e-1)" "unprognostic (4.20e-2)" "unprognostic (1.22e-1)" "prognostic favorable (3.93e-10)" "unprognostic (6.13e-3)" "unprognostic (2.43e-1)" "unprognostic (9.10e-3)" "unprognostic (1.57e-1)" 0.1 0.1 2.0 3.1 3.5 0.0 1.6 1.8 2.8 0.3 1.3 35.6 27.7 0.0 0.7 4.8 0.4 0.8 0.0 2.1 2.5 10.8 2.1 0.2 0.4 1.9 2.9 0.1 0.8 0.9 0.1 0.5 2.2 0.1 33.1 0.1 0.5 3.8 0.7 1.0 19.8 1.2 1.5 14.3 25.4 0.6 2.9 0.5 31.1 0.6 3.0 0.7 0.2 3.7 23.4 1.0 0.0 0.2 7.3 10.3 0.0 7.1 35.0 13.6 23.1 0.7 10.7 0.0 15.0 9.4 2.7 17.3 0.3 1.1 11.2 0.0 3.7 0.0 0.2 0.0 2.7 0.0 1.1 2.2 0.9 18.9 1.6 5.3 8.7 0.0 0.0 0.3 66.1 2.3 0.0 0.1 1.9 0.3 1.4 0.0 0.0 12.5 51.5 0.3 0.1 0.0 5.4 0.2 0.1 3.9 1.2 0.1 0.0 0.2 1.2 19.8 0.4 0.0 0.0 0.0 18.1 0.0 177.2 0.0 0.0 0.0 1.6 0.0 24.1 0.0 0.9 8.2 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.8 2.0 3.5 1.8 2.8 2.1 2.5 1.9 2.9 2.2 1.5 2.9 3.7 0.2 0.0 0.0 0.0 0.6 1.8 0.6 25.4 1.2 0.0 6.8 0.4 0.3 28.6 9.2 7.3 0.0 0.2 0.0 106.0 15.6 6.9 0.0 0.2 0.1 0.9 2.4 0.0 0.3 9.9 0.4 1.4 29.6 0.5 0.0 0.0 0.7 1.5 1.3 0.0 0.3 21.2 40.7 0.0 0.4 0.0 0.0 0.1 1.8 1.9 0.0 0.0 5.2 1.0 9.7 10.4 63.4 0.0 0.1 0.8 41.9 8.9 4.4 0.0 0.0 0.0 0.4 0.2 1.7 6.5 1.7 0.5 1.0 0.0 51.4 1.0 TMEM184A "MGC9712, SDMG1" ENSG00000164855 "Transmembrane protein 184A" Q6ZMB5 7 1542235-1560821 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 94.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 65.9;Intestinal goblet cells: 40.4;Paneth cells: 41.7;Proximal enterocytes: 60.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 34.2;RT4: 37.9;SCLC-21H: 40.8;SK-BR-3: 58.4;T-47d: 53.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053790, HPA071312" Uncertain Uncertain Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA053790: AB_2682263, HPA071312: AB_2686387" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.38e-1)" "unprognostic (4.41e-3)" "unprognostic (1.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (5.47e-2)" 0.4 0.3 0.1 1.4 0.1 0.7 3.0 0.1 1.0 20.6 0.2 12.1 24.4 1.1 0.3 94.6 7.0 3.6 0.4 0.0 0.2 6.2 24.4 2.2 0.2 0.2 0.0 0.2 22.9 5.2 11.4 1.7 0.1 11.3 6.6 0.1 22.5 4.5 4.9 37.0 23.6 0.3 0.0 0.1 12.6 3.7 0.2 0.6 0.6 0.6 4.3 12.8 41.0 0.1 23.7 15.0 0.1 0.0 0.0 0.1 5.0 0.8 0.3 0.9 0.1 20.9 25.4 0.5 7.6 0.3 7.5 17.0 0.0 9.7 0.3 0.2 0.9 0.1 15.3 9.7 0.2 0.0 0.0 0.0 8.9 0.3 8.0 0.4 0.1 6.3 0.2 0.1 0.0 34.2 0.2 0.1 0.7 13.5 19.3 0.5 0.0 10.9 7.3 37.9 40.8 0.1 6.4 58.4 0.1 0.5 53.7 0.1 0.0 0.0 8.2 9.7 1.1 0.1 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 1.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.1 2.9 3.2 4.4 0.0 1.6 4.0 5.8 7.2 2.2 1.1 12.1 5.5 7.5 11.5 18.2 9.2 0.0 7.1 1.4 65.9 1.9 13.2 0.0 19.3 3.4 1.4 7.2 0.0 0.3 11.0 8.7 1.7 23.4 31.7 1.3 0.5 0.0 14.2 0.8 0.0 0.1 40.4 14.2 0.6 2.6 0.0 0.0 1.4 0.0 0.0 0.6 0.5 0.0 0.0 0.0 13.1 41.7 0.0 4.6 10.4 60.5 5.1 28.0 0.6 0.0 1.8 3.0 0.0 0.1 15.4 9.2 16.8 1.2 0.1 19.4 16.0 TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.2;Hepatic stellate cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.7;NK-cell: 8.1" "Group enriched" "Detected in many" 10 "granulocytes: 3.7;NK-cells: 8.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" 10.3 2.9 9.8 2.3 11.7 5.2 8.9 7.8 12.4 6.9 7.1 11.0 2.7 5.6 13.7 5.6 5.4 4.5 9.6 10.3 10.1 6.0 3.4 11.3 3.0 9.9 9.7 4.9 3.5 0.9 2.6 7.4 10.0 5.2 7.2 0.6 7.7 2.2 3.2 3.6 6.8 3.2 8.8 9.3 4.9 2.2 10.5 2.0 5.6 2.3 1.6 5.3 5.9 9.2 11.1 9.1 13.4 14.2 4.8 16.2 11.8 8.2 15.3 6.8 10.8 5.0 21.8 2.0 38.9 10.0 20.3 12.6 4.5 6.4 4.6 18.1 6.3 12.4 10.6 3.8 8.7 3.9 18.9 10.0 6.8 15.4 6.8 32.8 28.2 12.1 3.4 0.5 22.9 10.1 5.9 9.9 6.9 11.1 14.8 11.5 8.4 0.3 7.2 6.3 3.7 7.7 6.1 1.9 12.6 5.6 9.0 8.5 33.7 20.8 7.6 6.4 11.2 1.5 1.2 4.0 31.4 15.0 10.4 3.7 0.2 0.2 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.2 0.0 0.2 0.4 8.1 0.3 0.4 0.0 0.0 9.8 11.7 7.8 12.4 10.3 10.1 9.9 9.7 10.0 8.8 10.5 9.2 22.0 0.0 2.3 3.3 2.1 0.5 3.3 4.9 1.8 0.9 2.8 2.3 1.7 1.5 6.0 5.5 2.1 9.5 1.7 31.2 0.0 5.7 0.6 2.3 3.7 23.8 6.0 4.0 12.7 4.9 4.0 6.0 22.4 2.0 17.7 10.6 53.2 0.6 3.5 0.0 5.4 25.2 6.1 1.3 3.4 0.3 3.1 1.5 1.8 12.2 0.1 0.5 2.1 2.5 1.5 14.9 21.0 1.9 1.3 6.0 3.9 0.4 7.5 0.6 6.6 1.8 3.6 0.5 6.5 2.4 0.6 8.8 1.9 6.0 21.0 6.3 TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.5;intestine: 136.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 325.6;Paneth cells: 221.6;Proximal enterocytes: 288.7;Respiratory ciliated cells: 133.9;Undifferentiated cells: 122.2;Urothelial cells: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.0;naive CD4 T-cell: 3.6;neutrophil: 11.7" "Group enriched" "Detected in many" 14 "granulocytes: 11.7;T-cells: 3.6" "Group enriched" "Detected in some" 5 "OE19: 333.1;RT4: 133.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA015474: , HPA015878: AB_2205046" "unprognostic (4.92e-3)" "unprognostic (7.94e-2)" "unprognostic (5.98e-2)" "unprognostic (1.81e-1)" "unprognostic (5.44e-3)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (6.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-3)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-2)" "unprognostic (2.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" 0.7 0.6 1.5 8.3 1.6 1.1 13.2 1.9 1.8 14.9 7.6 95.1 136.4 1.1 13.6 66.5 21.7 24.1 0.1 2.1 2.0 20.6 24.7 6.0 0.9 1.5 2.8 0.2 1.2 12.4 4.2 1.4 1.5 3.6 94.6 0.4 15.4 8.2 0.3 25.4 127.4 2.8 0.9 0.8 24.3 0.3 2.0 0.4 6.5 0.0 15.0 30.8 27.3 1.4 0.1 0.1 0.1 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 39.1 16.8 0.2 7.0 0.0 0.2 22.3 0.0 0.0 0.0 0.1 0.5 0.3 2.1 40.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.4 0.2 0.2 0.1 0.0 13.3 0.2 1.5 0.2 333.1 49.2 0.3 0.1 2.6 21.0 133.1 4.1 0.6 0.2 10.8 0.1 0.1 37.1 0.2 0.3 0.2 0.3 0.4 0.1 0.2 0.1 0.4 0.1 0.3 0.1 1.2 0.5 0.1 0.2 0.1 0.2 0.2 3.0 0.8 0.0 0.4 3.6 0.6 11.7 0.5 0.1 0.3 0.5 0.9 1.5 1.6 1.9 1.8 2.1 2.0 1.5 2.8 1.5 0.9 2.0 1.4 0.1 19.2 12.5 0.3 1.1 3.3 16.4 29.1 0.0 0.1 6.7 2.5 0.8 18.6 68.8 46.0 0.0 3.8 0.0 325.6 13.7 26.9 0.4 27.7 2.9 1.0 55.4 0.0 0.8 8.6 0.8 0.8 17.9 29.5 2.5 0.3 0.4 8.4 0.5 0.0 0.4 49.3 20.3 0.6 0.4 0.3 0.3 2.9 3.6 2.8 0.1 0.1 0.0 0.0 0.3 50.2 221.6 0.0 0.0 23.8 288.7 1.4 133.9 0.2 0.0 0.7 3.6 0.1 0.2 4.4 20.9 0.4 1.8 0.1 122.2 162.0 TMEM54 CAC-1 ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1231.3;Intestinal goblet cells: 357.2;Paneth cells: 800.1;Proximal enterocytes: 418.6;Undifferentiated cells: 355.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 198.9;OE19: 242.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA060864: , HPA061992: AB_2684652" "unprognostic (2.67e-1)" "unprognostic (2.57e-2)" "unprognostic (2.55e-1)" "unprognostic (4.98e-2)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (3.48e-2)" "unprognostic (9.43e-2)" "unprognostic (6.82e-3)" "unprognostic (2.13e-2)" "unprognostic (9.06e-2)" "unprognostic (3.12e-2)" "unprognostic (3.40e-2)" 19.2 15.6 68.2 39.9 64.2 0.0 24.6 61.3 98.4 59.0 52.8 268.0 116.0 40.4 26.6 145.3 25.5 62.0 18.7 64.1 70.0 44.3 14.9 26.8 4.6 70.5 68.8 20.3 31.8 49.5 22.6 18.4 64.8 58.2 113.2 4.2 54.0 22.9 6.9 116.0 123.1 21.3 67.8 13.2 108.0 11.9 65.5 2.4 47.8 4.9 13.0 51.1 78.6 66.4 133.3 33.9 0.0 32.0 59.1 35.4 119.9 20.0 29.2 43.1 55.2 84.7 198.9 0.0 57.1 24.8 55.2 80.0 28.6 107.4 12.8 158.3 6.4 0.2 11.3 4.5 42.9 0.4 2.0 30.5 96.2 66.1 18.1 29.1 19.3 13.0 18.7 0.1 22.7 135.6 0.1 2.6 10.3 242.7 60.8 17.7 52.2 0.6 16.2 159.8 1.8 17.1 14.4 82.1 44.0 19.3 89.3 24.2 39.9 42.3 47.5 95.9 40.8 5.2 12.4 15.8 30.1 3.3 61.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.2 64.2 61.3 98.4 64.1 70.0 70.5 68.8 64.8 67.8 65.5 66.4 6.4 19.2 27.6 3.9 6.6 20.4 92.3 36.9 20.5 8.2 82.0 61.0 4.7 97.2 36.9 47.8 4.2 42.8 1.3 1231.3 27.4 150.2 43.4 7.5 16.1 12.3 60.7 0.0 3.3 202.4 149.1 22.9 160.0 14.3 5.7 11.8 18.9 3.7 8.4 0.0 2.9 357.2 12.2 1.0 6.5 32.3 19.9 3.7 14.2 0.0 3.1 33.7 0.0 3.5 2.6 166.3 800.1 24.5 1.6 160.9 418.6 84.9 14.0 10.3 6.6 8.5 20.6 10.9 8.8 65.0 63.6 64.3 3.3 2.4 355.8 193.3 TMEM72 "bA285G1.3, C10orf127, KSP37" ENSG00000187783 "Transmembrane protein 72" A0PK05 10 44911316-44937010 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 51.2;kidney: 74.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 27.6;Distal enterocytes: 21.1;Distal tubular cells: 33.2;Late spermatids: 15.9;Paneth cells: 8.9" "Cancer enriched" "Detected in some" 8 "renal cancer: 8.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 123 "RPMI-8226: 44.0;U-937: 26.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039894, HPA062907" Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA039894: AB_10795261, HPA062907: AB_2684900" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.57e-2)" "unprognostic (3.24e-2)" "unprognostic (8.58e-2)" "unprognostic (5.45e-2)" "prognostic favorable (1.01e-4)" "unprognostic (4.99e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" 0.0 0.0 0.6 0.0 0.4 0.4 0.0 0.7 0.5 0.0 51.2 6.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 3.5 1.5 74.4 0.1 0.0 0.0 1.7 1.5 0.0 9.1 0.5 0.2 0.0 1.4 0.0 7.7 0.2 2.4 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.2 2.8 2.2 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.7 0.5 3.5 1.5 1.7 1.5 1.4 0.2 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 27.6 0.0 0.0 0.0 21.1 33.2 0.1 5.5 0.7 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 250.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 11 "dendritic cells: 4.1" "Cell line enhanced" "Detected in many" "CACO-2: 277.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA040473: AB_10794876, HPA053385: AB_2682134" "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.36e-3)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.14e-4)" "prognostic favorable (7.10e-4)" "unprognostic (6.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.41e-1)" "unprognostic (9.18e-3)" "prognostic favorable (3.85e-4)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" 56.3 50.6 48.9 17.3 84.1 4.7 44.5 75.3 64.1 68.6 161.9 90.0 102.5 100.4 74.2 27.9 96.5 93.9 44.3 51.2 56.9 36.5 27.5 58.1 5.7 72.8 77.4 191.9 88.5 53.7 23.9 28.2 69.7 80.7 96.3 15.7 50.1 23.9 5.3 24.6 118.4 62.3 51.9 19.6 101.6 20.7 75.0 4.4 47.7 14.6 7.7 50.7 42.6 109.3 7.4 27.2 115.5 0.2 154.7 138.0 1.1 114.2 153.2 59.2 126.5 277.6 8.1 1.6 1.7 144.0 2.1 0.9 74.2 30.1 34.5 24.7 92.0 4.6 0.1 124.5 71.5 0.3 1.7 116.3 29.7 74.7 12.1 31.6 154.8 40.7 78.1 0.3 162.9 0.2 0.1 0.7 77.0 83.1 42.0 0.2 108.4 0.5 13.6 49.0 9.8 158.3 2.7 0.0 89.8 72.6 36.5 0.2 128.2 83.8 78.1 1.0 0.2 9.2 3.8 0.1 42.9 0.1 46.2 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 4.1 0.0 0.1 48.9 84.1 75.3 64.1 51.2 56.9 72.8 77.4 69.7 51.9 75.0 109.3 7.6 41.7 24.8 6.2 0.6 25.1 76.1 111.5 27.3 1.4 32.4 104.5 14.1 72.9 61.0 46.0 0.0 8.1 0.7 109.2 5.9 81.0 18.2 14.7 48.5 7.8 97.9 2.7 0.6 66.4 7.3 127.2 40.8 12.1 3.8 87.8 29.6 13.0 5.7 0.0 0.3 145.7 40.7 0.6 15.9 14.9 120.5 2.0 44.4 1.9 0.0 106.3 0.0 3.0 173.0 88.2 97.9 151.6 0.2 68.1 250.9 37.2 54.6 4.8 65.7 22.1 55.5 40.7 27.7 17.1 12.6 7.1 2.4 132.6 166.6 68.6 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TMUB1 "C7orf21, HOPS, SB144" ENSG00000164897 "Transmembrane and ubiquitin like domain containing 1" Q9BVT8 7 151081085-151083493 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 191.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029429 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA029429: AB_10601825" "unprognostic (8.14e-2)" "unprognostic (2.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-3)" "unprognostic (7.73e-2)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "unprognostic (1.74e-2)" "unprognostic (2.24e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-3)" "unprognostic (2.74e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" 33.1 53.3 26.8 25.6 24.7 23.0 34.3 25.6 38.6 34.0 19.4 52.7 47.2 33.6 8.6 54.2 32.8 14.9 50.4 24.9 24.6 56.3 131.3 41.6 26.3 29.6 25.9 37.0 93.5 20.3 68.8 20.4 27.0 51.2 8.3 5.2 44.1 14.9 84.5 47.0 56.7 9.0 24.2 53.6 66.8 25.9 29.4 17.9 51.3 20.0 12.1 40.8 38.9 23.7 88.3 77.5 18.0 93.2 11.6 14.2 67.2 35.3 29.3 30.8 34.3 67.5 104.6 58.6 73.9 17.4 39.9 58.6 20.0 31.2 6.8 108.0 74.4 24.8 74.8 104.7 29.5 31.3 84.8 22.0 25.4 25.8 6.9 23.4 22.9 59.3 159.4 77.4 14.0 141.2 104.5 134.5 77.2 51.7 48.3 64.8 22.7 108.5 32.2 67.4 65.6 73.2 28.6 43.6 47.9 10.6 34.0 42.9 28.3 39.0 28.5 49.3 59.1 121.2 72.5 41.4 89.8 58.2 50.4 4.2 3.1 23.8 5.7 4.3 5.0 5.3 8.7 6.4 3.2 11.2 8.7 4.8 5.3 3.7 2.6 4.8 12.1 2.4 26.8 24.7 25.6 38.6 24.9 24.6 29.6 25.9 27.0 24.2 29.4 23.7 24.0 6.4 3.2 7.5 51.2 26.4 25.9 26.0 31.9 15.2 45.7 34.8 9.9 28.6 15.9 22.0 14.6 93.1 50.2 136.7 35.2 73.1 11.9 15.8 11.7 21.5 41.3 23.2 4.5 109.6 60.2 18.3 52.0 29.3 15.9 23.3 25.4 51.4 44.2 20.2 5.3 85.9 46.8 30.4 61.2 5.1 12.5 32.4 32.0 6.5 44.8 28.9 70.0 2.5 7.2 96.3 109.7 16.6 67.8 39.3 191.0 37.9 6.4 16.0 39.5 9.3 21.8 22.3 15.6 39.5 36.9 94.5 52.8 25.4 84.0 37.9 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 507.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" NA NA 17700 570000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010309: AB_2206639, HPA004102: AB_1846232" "unprognostic (2.19e-2)" "unprognostic (3.76e-2)" "unprognostic (8.14e-2)" "prognostic favorable (8.22e-4)" "unprognostic (3.07e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.50e-1)" "unprognostic (1.41e-3)" "unprognostic (1.00e-1)" "unprognostic (8.05e-2)" "unprognostic (4.78e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (5.14e-3)" "unprognostic (1.74e-1)" 166.5 133.3 33.7 76.7 34.4 42.4 120.0 35.3 38.6 105.0 47.8 114.1 101.5 111.8 23.0 105.6 106.7 88.8 80.6 32.4 40.3 94.5 176.5 130.7 38.1 45.7 40.4 90.6 57.3 53.7 57.3 82.4 39.6 86.9 56.4 3.5 76.0 46.3 91.0 103.7 109.5 97.5 40.4 111.3 84.4 22.6 39.7 39.2 97.4 63.1 36.1 113.2 113.2 37.4 40.2 296.4 40.9 60.2 277.7 282.0 75.7 82.2 143.0 108.2 93.9 34.7 153.6 3.7 28.9 179.3 85.6 107.1 12.9 96.4 74.1 0.8 25.3 20.3 79.2 82.2 245.5 104.4 66.9 291.8 94.4 90.2 131.4 250.4 134.1 42.0 33.7 29.8 126.3 57.1 34.0 100.0 102.1 146.1 87.6 27.9 66.6 32.4 83.7 70.7 0.1 2.1 117.8 60.9 62.5 103.6 16.4 111.4 146.0 84.6 71.7 64.7 78.4 0.1 10.6 12.8 100.5 95.9 107.0 17.1 165.8 93.5 62.2 130.4 60.0 0.5 25.1 51.0 123.7 0.4 22.3 34.0 507.2 9.7 111.5 31.6 26.2 117.3 33.7 34.4 35.3 38.6 32.4 40.3 45.7 40.4 39.6 40.4 39.7 37.4 102.0 51.3 37.1 15.3 4.8 123.0 115.8 127.3 81.4 0.4 50.1 35.9 9.3 67.2 70.8 27.6 0.0 62.0 35.5 204.0 15.6 98.7 1.2 25.5 66.5 111.8 33.6 30.1 4.6 119.4 120.2 109.3 43.8 42.3 7.6 27.6 159.2 145.0 176.4 0.0 1.3 56.8 32.6 146.7 113.4 5.4 102.2 102.4 71.2 32.8 127.1 15.9 104.0 11.1 0.9 116.6 239.4 65.8 4.2 141.2 227.5 96.9 30.8 0.7 124.9 64.1 89.4 1.3 1.1 57.0 134.7 148.6 31.2 21.5 57.4 140.1 TNIP1 "ABIN-1, KIAA0113, NAF1, VAN" ENSG00000145901 "TNFAIP3 interacting protein 1" Q15025 5 151029945-151093577 "Human disease related genes, Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 265.5;Proximal enterocytes: 257.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 406.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037893, HPA037894, HPA071950" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA037893: AB_10672468, HPA037894: AB_2675723, HPA071950: AB_2686476" "prognostic favorable (5.69e-4)" "unprognostic (1.08e-1)" "unprognostic (1.10e-1)" "prognostic favorable (6.86e-5)" "unprognostic (7.45e-3)" "unprognostic (2.94e-1)" "unprognostic (5.35e-3)" "unprognostic (1.45e-2)" "unprognostic (2.82e-1)" "unprognostic (3.42e-1)" "unprognostic (2.25e-2)" "unprognostic (1.96e-1)" "unprognostic (7.68e-3)" "unprognostic (1.47e-1)" "unprognostic (4.69e-2)" "unprognostic (2.29e-1)" "unprognostic (9.84e-2)" 120.0 49.7 34.1 79.6 33.4 128.0 90.7 35.3 40.8 60.1 33.3 72.7 73.2 37.6 22.4 89.3 37.9 54.3 96.3 31.5 36.5 83.3 107.9 91.7 69.4 40.5 37.4 41.8 71.6 42.8 27.2 28.7 39.0 47.9 52.4 17.4 53.1 39.2 211.2 60.4 90.8 32.6 37.6 101.2 63.5 14.6 37.1 43.4 45.9 130.7 83.3 84.4 69.3 35.3 117.7 81.3 15.4 55.7 58.4 58.6 39.4 54.7 174.5 48.6 91.1 78.4 155.5 95.8 182.3 74.2 285.3 68.3 25.2 406.4 59.4 167.8 34.6 37.8 44.4 51.1 111.4 43.6 168.3 84.3 74.5 80.3 166.2 134.1 69.1 37.2 24.6 94.2 122.7 43.7 48.2 60.0 13.9 41.1 43.4 39.0 118.4 131.4 152.3 85.0 21.7 49.9 42.4 131.5 57.2 41.6 67.5 54.5 107.8 162.7 53.0 28.7 79.2 184.6 102.2 43.4 177.0 63.7 39.6 18.2 12.1 36.0 11.9 11.1 14.0 12.7 13.9 12.0 9.2 16.8 7.1 7.9 41.3 12.4 10.8 12.8 21.2 10.4 34.1 33.4 35.3 40.8 31.5 36.5 40.5 37.4 39.0 37.6 37.1 35.3 31.1 57.7 45.4 4.9 73.1 29.7 50.4 119.9 27.3 14.3 33.3 24.9 48.8 54.3 72.2 27.6 4.2 18.3 53.7 233.7 72.4 218.0 3.3 39.8 18.0 75.1 37.3 52.4 6.5 139.1 31.3 38.9 92.8 64.8 48.2 105.2 42.1 62.7 39.0 18.5 6.4 69.0 46.8 49.6 113.1 6.9 27.1 64.9 26.6 8.4 238.3 20.3 68.0 5.5 9.4 265.5 173.9 23.7 63.6 179.1 257.5 56.4 49.1 15.0 32.9 69.2 45.7 2.2 13.9 30.2 28.6 48.2 60.7 12.2 77.1 158.6 TOR4A "C9orf167, FLJ20245" ENSG00000198113 "Torsin family 4 member A" Q9NXH8 9 137277726-137282641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 45.6;Undifferentiated cells: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 45.4;TIME: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044913 Enhanced Approved Nucleoplasm NA NA 260000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA044913: AB_10965030" "unprognostic (1.95e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.99e-1)" "unprognostic (3.56e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (5.42e-3)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (1.11e-2)" "unprognostic (2.24e-1)" "unprognostic (5.20e-2)" "unprognostic (2.00e-3)" "unprognostic (4.39e-3)" "unprognostic (7.93e-3)" "unprognostic (2.56e-1)" 4.4 2.9 2.2 4.9 1.9 2.8 2.4 1.9 1.9 4.8 2.0 12.4 9.6 3.6 0.8 7.5 4.2 5.2 13.0 1.6 1.8 11.7 2.9 10.9 4.1 2.8 2.3 5.1 3.8 1.9 1.9 1.9 2.5 2.3 4.3 0.0 1.6 2.5 1.4 1.7 11.0 1.3 2.6 15.4 12.5 0.6 3.2 0.8 4.2 0.7 3.0 3.8 3.8 2.3 16.7 21.6 0.2 0.6 0.2 1.7 1.7 27.0 18.5 12.3 6.5 2.7 30.8 1.6 37.4 9.7 0.9 34.0 0.1 9.0 4.2 1.4 1.4 18.2 15.4 14.8 25.9 8.0 45.4 0.9 9.3 2.5 4.8 13.9 16.8 0.1 27.8 2.1 2.1 1.8 0.0 22.0 2.6 18.0 23.9 4.4 5.8 11.3 14.7 0.1 0.8 0.2 19.7 0.1 0.5 0.5 1.6 24.7 41.7 0.6 14.6 2.9 4.6 0.2 1.2 10.5 4.6 7.3 6.0 0.5 0.7 1.3 0.1 0.7 0.2 0.2 0.1 0.0 0.5 0.4 0.0 0.0 0.4 0.2 1.2 0.0 0.2 0.3 2.2 1.9 1.9 1.9 1.6 1.8 2.8 2.3 2.5 2.6 3.2 2.3 10.5 0.0 5.9 0.0 6.2 2.7 3.0 4.9 2.2 0.1 1.9 4.6 8.1 22.8 6.3 12.9 0.0 0.2 4.1 45.6 0.0 10.4 0.1 4.6 2.4 8.4 7.2 5.2 0.0 2.2 0.2 1.9 21.4 9.6 10.2 0.0 27.8 1.0 15.0 0.0 0.0 24.7 2.0 22.0 17.7 0.1 2.5 16.2 0.0 2.8 16.1 0.7 15.5 0.0 0.0 22.9 29.4 4.1 2.4 1.7 17.9 0.6 7.5 0.6 19.7 1.5 3.1 0.0 0.7 2.2 2.4 0.0 2.9 4.3 34.7 15.4 TP53I3 PIG3 ENSG00000115129 "Tumor protein p53 inducible protein 3" Q53FA7 2 24077433-24085861 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 119.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.8;Late spermatids: 213.9;Proximal enterocytes: 200.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "T-47d: 599.7" "Low region specificity" "Detected in all" "CAB017479, HPA022012, HPA028742" Enhanced Supported Vesicles NA NA 250000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB017479: AB_2303667, HPA022012: AB_1858202, HPA028742: AB_10603456" "unprognostic (3.66e-2)" "unprognostic (1.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-3)" "unprognostic (4.47e-1)" "unprognostic (1.09e-2)" "unprognostic (1.53e-3)" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (9.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-1)" "unprognostic (3.67e-2)" "unprognostic (8.57e-3)" 20.2 24.6 8.6 16.1 9.8 20.0 17.2 8.4 9.6 29.6 11.2 54.4 51.5 17.3 4.5 119.2 16.5 26.3 15.4 7.5 9.0 46.8 15.2 29.9 7.2 9.4 11.1 8.2 40.1 7.0 11.7 10.6 8.5 15.0 40.8 2.0 25.3 11.2 6.2 8.0 69.1 16.9 7.7 11.9 25.3 38.4 13.0 14.2 23.6 5.9 10.1 22.3 63.8 9.7 27.5 86.8 50.6 21.1 38.8 85.3 37.2 27.3 32.3 22.6 31.1 22.1 48.4 3.5 15.0 44.0 6.1 8.0 13.1 46.5 13.8 21.6 2.0 8.7 33.3 57.5 25.2 4.1 15.3 92.3 72.3 60.2 14.7 46.1 102.0 16.3 7.3 23.4 95.5 18.1 5.0 0.6 39.2 30.8 36.0 10.1 45.7 0.9 38.1 41.4 7.2 32.9 35.1 7.8 6.1 40.5 599.7 5.6 80.6 26.9 63.8 18.5 13.7 10.6 7.4 3.0 8.9 0.4 7.0 11.8 19.1 16.9 0.2 12.6 0.2 4.9 0.2 0.6 16.0 5.5 0.1 0.4 4.1 0.3 5.6 7.1 0.5 6.1 8.6 9.8 8.4 9.6 7.5 9.0 9.4 11.1 8.5 7.7 13.0 9.7 19.2 28.9 38.4 3.9 6.8 4.7 24.7 69.7 6.8 0.8 25.8 33.0 9.0 50.1 51.9 42.3 0.0 41.9 1.1 175.8 109.5 93.5 127.8 50.4 47.4 20.3 79.4 7.2 0.4 134.7 31.9 30.6 83.6 68.2 12.7 85.8 23.9 12.9 45.0 0.0 0.4 63.9 57.0 22.9 11.1 213.9 7.8 20.9 14.2 4.7 23.9 9.5 0.0 5.0 0.3 91.1 138.5 9.1 8.0 11.4 200.9 104.7 19.2 1.9 19.7 14.1 36.8 56.6 14.3 38.8 7.0 28.9 3.4 16.2 75.2 49.9 TP53INP2 "C20orf110, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH" ENSG00000078804 "Tumor protein p53 inducible nuclear protein 2" Q8IXH6 20 34704339-34713439 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 517.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 143.5;Early spermatids: 208.6;Late spermatids: 353.7;Paneth cells: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 13 "granulocytes: 2.7" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 219.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.33e-2)" "unprognostic (2.57e-3)" "unprognostic (1.26e-1)" "unprognostic (3.08e-2)" "unprognostic (2.07e-1)" "unprognostic (1.86e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-1)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (1.52e-2)" "unprognostic (2.57e-2)" "prognostic favorable (1.26e-8)" "unprognostic (8.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.93e-2)" "unprognostic (6.17e-2)" 19.7 28.0 315.7 11.1 439.0 89.7 13.8 343.9 403.1 19.6 159.7 42.2 19.9 26.4 15.7 64.8 19.3 23.8 85.5 233.8 348.8 31.8 45.6 19.6 5.6 517.3 444.7 15.5 16.6 35.1 22.0 10.5 464.6 36.9 38.4 45.9 27.6 31.2 53.1 12.3 23.5 34.7 418.6 6.6 24.4 39.9 376.8 2.9 31.6 94.0 17.2 33.0 23.8 485.7 2.5 3.0 9.8 12.6 22.1 18.1 4.2 9.8 30.9 12.8 10.6 17.3 1.2 7.7 6.6 19.6 25.1 1.9 20.8 4.7 14.0 2.3 2.6 14.0 8.2 16.9 28.6 2.2 10.9 52.3 7.0 10.1 1.4 16.0 20.2 6.9 5.8 24.8 14.5 3.4 1.6 4.8 1.3 2.1 7.4 7.4 6.4 12.4 16.1 8.8 21.4 24.1 8.7 219.0 15.2 11.6 15.8 10.3 15.3 35.0 12.0 4.6 4.1 9.8 12.5 6.2 22.2 31.2 12.5 0.5 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 315.7 439.0 343.9 403.1 233.8 348.8 517.3 444.7 464.6 418.6 376.8 485.7 9.5 3.2 10.6 5.5 8.1 3.7 17.0 11.7 5.7 20.4 17.4 12.3 75.4 15.7 16.7 3.7 52.1 1.7 12.8 143.5 5.9 16.5 208.6 19.6 10.1 10.4 52.4 0.4 4.3 23.9 1.1 9.6 46.9 24.2 7.0 7.5 11.0 28.7 5.3 32.0 6.1 59.5 32.6 10.2 3.6 353.7 7.5 15.5 5.4 2.8 2.6 10.9 0.0 1.0 17.7 24.3 116.1 13.2 7.4 15.3 34.0 8.9 25.1 55.8 19.7 35.9 27.4 4.0 2.7 4.5 3.0 28.5 8.4 9.1 23.9 24.4 TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;pancreas: 91.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 177.7;Proximal enterocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 61.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 23.6" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA020899: AB_1845835, HPA076667: " "unprognostic (5.41e-2)" "prognostic favorable (2.13e-4)" "unprognostic (2.94e-1)" "unprognostic (9.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (3.59e-3)" "unprognostic (8.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.89e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.16e-9)" "unprognostic (1.96e-3)" "unprognostic (6.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" 3.7 5.1 24.3 4.4 37.8 2.7 4.8 29.9 33.1 5.2 15.1 25.4 22.0 4.7 0.9 20.5 5.1 3.2 10.7 23.5 23.7 19.1 24.3 8.1 2.4 33.1 32.4 6.4 91.4 2.5 6.0 3.3 28.2 8.0 6.9 1.7 11.8 3.4 6.2 15.6 26.0 1.5 20.8 5.0 29.3 9.3 31.9 2.0 5.5 3.1 1.5 7.8 6.9 56.4 10.2 11.4 3.8 17.0 5.2 5.5 30.1 7.0 4.3 7.0 3.9 38.5 12.1 18.6 10.1 3.6 9.2 30.4 7.9 3.9 0.9 11.9 11.1 8.7 17.5 25.5 7.9 13.5 10.8 4.7 7.5 6.2 4.3 4.6 4.5 8.2 16.1 6.4 2.1 61.9 8.9 29.0 13.5 55.5 14.8 26.3 9.1 28.4 15.9 21.0 24.4 8.9 10.8 49.6 13.0 2.9 57.8 21.0 5.0 12.7 6.0 20.1 15.1 5.3 11.0 9.7 9.1 12.1 7.2 0.0 0.8 0.0 0.3 0.8 0.1 0.3 0.3 0.5 0.6 0.3 0.1 0.3 0.0 0.8 0.4 0.6 0.6 0.2 24.3 37.8 29.9 33.1 23.5 23.7 33.1 32.4 28.2 20.8 31.9 56.4 4.6 19.2 5.5 6.2 3.5 1.8 1.3 2.6 2.2 19.3 13.2 9.5 7.6 15.7 2.6 16.5 6.2 5.4 8.4 177.7 7.9 8.0 3.1 7.6 4.1 2.9 9.0 7.4 3.3 45.4 1.3 3.0 15.3 9.6 1.3 8.7 3.9 19.5 3.6 11.8 3.8 46.0 6.1 2.8 1.6 5.3 3.4 5.2 5.4 1.0 2.8 12.4 1.0 2.5 30.4 15.3 39.7 4.5 1.9 3.3 95.9 20.0 2.3 7.3 6.6 3.2 4.5 2.7 4.4 5.8 2.8 1.9 4.5 10.3 36.7 1.7 TRIM15 "RNF93, ZNF178, ZNFB7" ENSG00000204610 "Tripartite motif containing 15" Q9C019 6 30163206-30172693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 17.1;kidney: 6.0;liver: 14.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 139.1;Intestinal goblet cells: 41.5;Paneth cells: 332.0;Proximal enterocytes: 80.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 14.4;liver cancer: 5.6;pancreatic cancer: 7.7;renal cancer: 4.4;stomach cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HEL: 16.5;Hep G2: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047527 Approved "Centriolar satellite,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Centriolar satellite" "HPA047527: " "unprognostic (2.61e-1)" "unprognostic (1.54e-1)" "unprognostic (1.85e-1)" "unprognostic (1.71e-1)" "unprognostic (5.36e-2)" "unprognostic (1.92e-2)" "unprognostic (7.57e-4)" "unprognostic (5.27e-2)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (3.83e-1)" "unprognostic (1.63e-1)" "unprognostic (2.41e-1)" 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.8 17.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 6.0 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.7 12.2 0.3 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 11.5 0.0 0.0 0.0 0.0 0.0 139.1 1.9 1.8 0.0 0.0 0.1 0.0 0.0 2.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 41.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 332.0 0.0 0.0 0.0 80.0 21.5 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.5 0.0 29.1 0.0 TRIM31 "C6orf13, HCG1, HCGI, RNF" ENSG00000204616 "Tripartite motif containing 31" Q9BZY9 6 30102897-30113090 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 22.1;stomach 1: 6.0;urinary bladder: 8.6" "Group enriched" "Detected in some" 4 "Distal enterocytes: 409.1;Paneth cells: 404.9;Proximal enterocytes: 193.3;Urothelial cells: 227.9" "Group enriched" "Detected in many" 5 "cervical cancer: 6.7;colorectal cancer: 25.8;pancreatic cancer: 11.4;stomach cancer: 19.8;urothelial cancer: 12.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 726 "RT4: 294.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA074175 Enhanced NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA074175: " "unprognostic (1.37e-1)" "unprognostic (7.78e-3)" "unprognostic (1.83e-1)" "unprognostic (7.05e-3)" "unprognostic (1.75e-1)" "unprognostic (9.37e-2)" "unprognostic (6.13e-2)" "unprognostic (1.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.11e-2)" "unprognostic (1.97e-2)" "unprognostic (1.92e-1)" "unprognostic (1.43e-3)" "unprognostic (5.84e-3)" "unprognostic (6.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 22.1 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.4 12.1 0.1 0.0 0.0 6.0 3.3 0.0 0.0 0.0 0.0 0.0 8.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 294.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.6 0.1 12.3 2.5 0.0 0.0 0.4 0.3 5.7 4.3 3.0 0.0 0.0 0.0 0.2 409.1 0.0 2.7 0.2 25.7 0.2 0.4 5.4 2.7 0.0 1.7 0.0 0.3 73.9 1.1 4.5 0.0 0.0 0.0 0.1 0.0 0.0 52.3 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 404.9 0.0 0.2 2.7 193.3 0.6 14.2 0.0 0.0 0.2 0.5 1.8 0.2 0.0 0.0 0.0 0.8 0.0 25.6 227.9 TRIM40 RNF35 ENSG00000204614 "Tripartite motif containing 40" Q6P9F5 6 30136124-30148735 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 3.0;liver: 1.6;testis: 1.4" "Group enriched" "Detected in some" 5 "Distal enterocytes: 20.1;Paneth cells: 24.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.7;stomach cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HEL: 1.1" "Region enriched" "Detected in single" 18 "thalamus: 3.1" "Low region specificity" "Detected in many" HPA043818 Uncertain Approved Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043818: AB_10963090" "unprognostic (2.88e-1)" "unprognostic (5.20e-2)" "unprognostic (4.11e-1)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (4.84e-2)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 24.7 0.0 0.0 0.0 3.8 0.5 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.6;intestine: 16.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 128.9;Glandular and luminal cells: 36.5;Microglial cells: 39.4;Oligodendrocytes: 81.1;Proximal enterocytes: 23.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 23.1;neutrophil: 7.5" "Lineage enriched" "Detected in single" 41 "granulocytes: 23.1" "Cell line enhanced" "Detected in some" "BEWO: 3.8;HeLa: 2.4;Karpas-707: 1.3;RT4: 3.8;U-266/70: 1.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" 0.6 0.0 2.1 0.6 3.5 2.6 0.6 3.0 2.4 0.3 0.2 13.2 7.0 0.3 0.2 0.3 0.2 0.3 0.2 1.6 2.8 1.9 0.1 0.3 0.3 4.2 3.4 0.0 0.1 1.4 0.5 0.3 4.1 0.5 16.6 0.4 0.3 0.1 0.1 0.7 7.9 0.5 2.7 0.5 0.2 1.4 3.1 0.4 0.2 0.1 0.3 0.4 0.3 6.6 0.0 0.8 0.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 0.1 2.4 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.1 0.0 1.4 0.0 0.1 0.0 0.1 0.1 23.1 0.1 2.4 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 7.5 0.5 0.2 0.3 0.0 0.1 2.1 3.5 3.0 2.4 1.6 2.8 4.2 3.4 4.1 2.7 3.1 6.6 3.3 0.0 1.7 1.0 0.3 0.1 1.9 0.3 2.2 0.3 0.2 0.4 0.9 0.0 1.3 3.7 0.0 0.2 0.2 128.9 0.0 0.0 4.0 11.3 3.4 3.2 3.6 0.0 1.3 0.0 0.1 0.3 0.0 36.5 0.0 0.1 3.3 0.1 0.0 0.0 0.5 3.0 0.0 0.3 0.6 0.9 0.0 0.4 0.0 39.4 0.0 0.3 0.0 0.5 81.1 0.0 13.8 0.4 0.1 1.3 23.3 0.0 0.8 2.7 0.0 0.7 0.4 1.6 2.4 0.5 1.0 0.1 0.5 0.2 7.5 0.8 TSPAN1 "NET-1, TSPAN-1" ENSG00000117472 "Tetraspanin 1" O60635 1 46175073-46185962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 593.8;kidney: 244.3" "Cell type enhanced" "Detected in many" "Club cells: 723.5;Distal enterocytes: 1983.8;Late spermatids: 838.1;Paneth cells: 1127.7;Respiratory ciliated cells: 1817.6" "Cancer enhanced" "Detected in all" "prostate cancer: 455.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 57 "plasmacytoid DC: 5.6" "Lineage enriched" "Detected in single" 57 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "A-431: 129.6;CAPAN-2: 216.7;HaCaT: 151.4;hTCEpi: 173.6;OE19: 257.9;RPTEC TERT1: 628.4;RT4: 308.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA011909 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA011909: AB_2668565" "unprognostic (1.21e-1)" "unprognostic (3.11e-1)" "unprognostic (3.67e-2)" "unprognostic (4.12e-1)" "unprognostic (2.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.28e-6)" "unprognostic (5.90e-2)" "unprognostic (2.61e-1)" "unprognostic (4.90e-2)" "unprognostic (4.30e-2)" 1.9 4.3 0.5 53.2 0.7 0.0 6.2 1.7 1.1 78.2 1.4 523.3 25.4 17.7 34.7 5.5 122.4 28.9 0.9 0.5 0.5 244.3 3.9 32.1 0.4 1.2 0.6 0.4 3.1 72.0 17.3 1.1 1.1 194.7 593.8 0.0 101.0 65.9 0.8 2.5 96.7 20.8 1.0 0.7 213.1 27.3 0.6 1.9 121.9 0.1 4.9 104.9 9.9 1.8 129.6 2.0 0.0 0.0 0.2 0.0 1.8 0.1 2.7 0.1 0.0 0.0 216.7 0.0 40.2 0.3 0.2 151.4 0.0 111.2 0.1 0.0 0.0 0.0 1.1 7.6 0.0 0.0 0.2 0.0 173.6 0.7 60.9 3.6 0.3 1.3 0.0 0.0 1.6 4.9 0.0 0.5 0.1 257.9 8.1 0.1 0.1 1.6 628.4 308.2 1.9 0.0 0.3 13.0 0.5 0.5 9.0 0.1 1.4 0.0 0.7 0.4 0.7 1.5 0.1 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.5 0.7 1.7 1.1 0.5 0.5 1.2 0.6 1.1 1.0 0.6 1.8 2.5 25.6 29.5 0.3 7.4 1.0 194.4 499.9 4.0 0.0 14.5 11.0 0.7 11.5 723.5 579.4 0.0 0.3 0.2 1983.8 46.9 61.3 141.3 268.3 14.1 4.5 201.8 0.0 1.2 525.1 0.1 6.0 223.3 144.3 11.4 0.0 1.4 3.6 0.3 0.0 1.3 648.1 242.1 0.3 0.3 838.1 5.0 5.3 5.4 1.0 1.6 0.0 0.0 0.5 1.6 484.4 1127.7 1.9 0.7 211.7 505.4 477.8 1817.6 0.0 0.0 0.4 54.1 4.7 2.6 2.9 1.3 0.0 7.4 0.0 275.9 517.0 TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 705.9;Muller glia cells: 508.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 481.0;naive B-cell: 488.1;plasmacytoid DC: 313.2" "Group enriched" "Detected in all" 5 "B-cells: 488.1;dendritic cells: 313.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" 333.8 143.9 257.2 87.3 248.9 33.3 143.3 253.4 292.4 138.2 288.7 364.2 342.1 130.9 432.8 78.4 249.8 186.2 108.8 247.8 296.3 211.3 87.4 202.1 88.0 250.0 267.7 148.1 140.2 283.4 189.7 111.6 260.2 96.2 386.3 418.6 152.2 187.3 429.1 78.3 349.2 128.3 266.7 84.8 221.2 84.8 282.5 71.6 200.3 374.4 106.9 170.1 67.4 281.3 130.6 347.6 282.8 179.3 484.7 295.8 93.3 203.7 220.2 245.1 265.7 213.5 264.7 126.9 294.8 211.6 234.0 289.0 271.2 139.5 182.9 143.4 410.4 91.0 252.5 204.4 234.5 118.4 64.3 280.9 165.5 135.8 120.1 372.6 304.8 83.1 98.0 109.2 243.3 49.5 105.7 112.1 200.5 414.7 152.4 130.8 351.0 135.3 408.0 73.0 255.0 282.1 139.8 116.9 393.7 269.3 125.0 220.8 292.1 225.7 88.4 138.0 290.7 237.4 346.6 67.1 200.1 173.5 131.9 8.8 51.3 10.4 32.6 69.6 34.1 481.0 16.5 23.9 99.2 488.1 42.6 39.3 4.8 60.3 77.1 313.2 4.6 95.2 257.2 248.9 253.4 292.4 247.8 296.3 250.0 267.7 260.2 266.7 282.5 281.3 76.1 112.2 213.4 69.5 83.8 34.7 77.5 114.6 36.5 247.7 43.6 32.3 98.2 108.7 169.0 68.0 183.5 89.9 41.3 705.9 25.4 250.2 28.5 86.1 63.4 57.6 91.3 19.4 47.8 354.0 35.6 90.8 85.1 41.7 23.4 88.6 53.6 29.5 65.4 127.9 54.3 290.4 97.6 58.0 27.5 57.9 64.3 38.2 72.9 29.0 35.1 508.9 36.0 116.6 32.7 245.1 410.7 51.6 81.2 220.1 364.3 65.5 201.7 185.1 26.3 44.8 189.0 108.0 64.6 34.2 34.2 75.9 19.4 149.5 205.2 381.4 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TSTD1 KAT ENSG00000215845 "Thiosulfate sulfurtransferase like domain containing 1" Q8NFU3 1 161037631-161038977 "Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 684.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 205.3;OE19: 215.1;SK-BR-3: 284.0;T-47d: 274.9;U-266/70: 315.4;U-266/84: 243.2" "Region enriched" "Detected in some" 4 "olfactory bulb: 6.6" "Low region specificity" "Detected in all" "HPA006518, HPA006655" Approved Approved "Cytosol,Cytoplasmic bodies" NA NA 57000 "Cluster 37: B-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cytosol, Cytoplasmic bodies" "HPA006518: AB_2667608, HPA006655: AB_10600919" "unprognostic (6.10e-2)" "unprognostic (4.70e-2)" "unprognostic (1.93e-1)" "unprognostic (4.43e-2)" "unprognostic (5.77e-2)" "unprognostic (1.63e-1)" "unprognostic (6.56e-2)" "unprognostic (2.51e-3)" "unprognostic (2.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-2)" "unprognostic (1.13e-1)" "unprognostic (4.64e-2)" "unprognostic (2.38e-2)" "unprognostic (2.83e-2)" "unprognostic (8.57e-3)" "unprognostic (8.88e-3)" 33.8 72.1 28.3 25.8 31.4 48.3 73.6 19.8 40.3 31.4 34.6 60.3 40.4 10.4 101.5 91.3 69.2 18.9 55.4 28.2 28.0 125.3 74.7 47.4 52.8 21.2 23.4 55.1 93.5 167.2 119.2 13.2 23.2 98.6 40.8 11.4 175.7 43.5 38.7 79.6 50.5 8.5 20.8 39.7 61.3 35.6 27.3 59.5 140.0 18.6 51.2 29.9 46.4 24.9 119.8 1.6 0.3 0.6 0.0 0.0 2.1 0.2 0.0 0.2 0.0 11.1 112.5 25.0 67.9 0.0 0.0 107.2 0.1 46.4 0.0 98.4 84.9 13.3 43.2 0.0 12.2 43.7 0.9 0.6 28.2 0.0 4.8 0.1 15.6 100.8 0.4 130.8 12.8 205.3 118.6 0.6 0.7 215.1 0.3 38.7 0.0 184.8 98.0 32.8 67.5 37.2 0.0 284.0 0.9 54.0 274.9 0.6 0.5 0.0 41.5 0.6 4.8 315.4 243.2 26.3 0.3 0.2 0.4 438.2 24.2 357.7 226.5 72.0 218.8 530.9 296.2 252.0 72.6 506.1 333.3 282.1 337.5 306.5 104.8 203.9 410.8 220.6 28.3 31.4 19.8 40.3 28.2 28.0 21.2 23.4 23.2 20.8 27.3 24.9 6.5 253.2 228.8 1.0 170.3 86.3 307.5 331.1 160.5 16.2 443.9 457.1 68.4 223.1 259.0 367.8 27.1 271.5 101.2 478.1 684.8 169.7 16.3 336.9 29.2 14.0 218.5 29.0 5.8 151.5 112.7 35.8 59.1 201.2 124.7 88.7 10.8 149.3 72.3 3.3 1.9 418.1 402.8 18.7 116.2 25.1 8.4 40.7 151.2 1.9 178.3 73.0 206.0 1.0 0.7 131.5 383.6 9.8 110.5 386.2 426.6 665.8 615.1 31.8 19.7 99.5 37.7 73.3 44.4 199.6 135.8 151.0 149.3 31.7 267.0 384.9 TTC22 FLJ20619 ENSG00000006555 "Tetratricopeptide repeat domain 22" Q5TAA0 1 54779712-54801323 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.6;vagina: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 72.4;Gastric mucus-secreting cells: 23.0;Intestinal goblet cells: 27.1;Paneth cells: 36.9;Proximal enterocytes: 51.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 9.0;CAPAN-2: 10.7;HaCaT: 12.3;hTCEpi: 6.9;OE19: 14.7;RPMI-8226: 8.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035072 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA035072: AB_10602252" "prognostic favorable (2.06e-4)" "unprognostic (8.52e-2)" "unprognostic (4.84e-2)" "unprognostic (4.98e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.07e-2)" "unprognostic (4.57e-2)" "unprognostic (7.27e-2)" "unprognostic (1.51e-3)" "unprognostic (5.08e-3)" "unprognostic (1.00e-1)" "unprognostic (3.16e-2)" "unprognostic (2.21e-1)" 0.4 0.9 1.0 2.4 3.2 1.4 2.6 0.7 1.9 21.7 2.6 14.5 15.7 1.5 2.7 109.6 3.4 2.7 0.2 1.0 2.4 9.3 6.1 2.1 1.6 0.7 0.7 0.4 9.4 16.5 6.1 0.2 0.7 6.3 11.2 0.2 17.5 1.7 0.6 25.0 17.4 0.7 0.5 2.0 13.1 0.7 2.2 2.3 4.1 0.0 7.2 3.7 48.1 0.7 9.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.9 10.7 0.1 0.4 0.0 0.0 12.3 0.0 3.6 0.0 4.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.1 14.7 1.1 0.1 0.1 8.1 0.5 2.2 0.3 0.2 0.7 0.1 0.0 0.2 0.4 0.2 0.1 0.1 0.0 0.2 0.1 0.8 2.2 0.1 0.1 0.1 0.0 1.0 0.0 2.5 3.4 0.0 2.0 0.7 1.6 3.7 0.0 0.5 1.4 1.7 1.3 1.6 0.0 0.0 2.7 0.5 1.0 3.2 0.7 1.9 1.0 2.4 0.7 0.7 0.7 0.5 2.2 0.7 0.0 0.0 3.1 0.0 1.8 1.3 5.9 3.2 3.4 0.0 3.9 3.6 2.7 15.7 4.5 3.7 0.0 0.3 5.9 72.4 7.9 5.0 2.7 3.3 0.4 0.3 2.4 2.7 0.3 9.1 0.4 0.5 23.0 3.2 0.0 0.0 0.4 2.2 0.0 0.0 0.1 27.1 4.1 0.0 0.3 1.1 0.3 0.4 1.8 0.0 0.0 0.0 7.2 0.0 0.1 10.5 36.9 0.0 1.0 6.0 51.7 8.9 5.7 0.0 0.0 0.0 0.4 0.4 0.9 19.7 4.5 0.0 4.1 0.1 15.4 13.9 TUBA1C "bcm948, MGC10851, MGC14580, TUBA6" ENSG00000167553 "Tubulin alpha 1c" Q9BQE3 12 49188736-49274600 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 479.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 98.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 4114.3" "Low region specificity" "Detected in all" "HPA039247, HPA043684, HPA063394" Supported Supported Microtubules NA Yes 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic unfavorable (2.90e-4)" "unprognostic (1.15e-2)" "prognostic favorable (7.37e-5)" "unprognostic (3.25e-2)" "unprognostic (4.60e-2)" "unprognostic (2.88e-2)" "prognostic unfavorable (8.48e-8)" "prognostic unfavorable (6.85e-4)" "unprognostic (2.11e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (5.64e-6)" "unprognostic (1.49e-1)" "prognostic unfavorable (6.26e-7)" "unprognostic (2.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.49e-1)" "unprognostic (5.45e-3)" 92.6 57.8 12.4 110.5 12.1 148.8 54.7 13.9 18.0 101.0 41.9 158.2 106.9 59.6 62.7 479.4 50.8 92.1 55.3 12.8 16.4 113.5 69.3 74.1 78.6 15.7 14.1 38.3 52.6 22.5 28.0 109.9 15.5 43.7 156.5 2.5 139.0 46.4 45.3 166.1 117.6 129.8 15.7 42.1 115.2 26.3 22.6 103.3 56.3 42.5 170.7 222.5 168.8 15.4 1295.3 987.5 211.7 363.9 220.5 368.4 816.3 1010.1 1126.1 1742.1 927.3 966.9 947.0 578.9 1053.2 1194.2 1047.3 580.5 1246.0 1412.1 1150.2 564.1 449.7 703.4 406.7 943.7 165.2 550.9 498.4 269.8 663.0 1485.6 619.9 550.6 1139.5 320.6 1026.8 308.3 1521.8 811.1 306.5 535.8 639.6 4114.3 1928.6 344.0 414.5 319.7 770.3 602.8 169.8 9.1 875.5 574.4 386.0 828.3 559.4 426.0 835.1 819.3 911.5 821.9 1717.4 101.6 306.5 565.2 431.6 536.1 725.9 98.8 14.6 29.9 12.3 17.3 19.7 10.5 13.1 11.7 27.0 7.4 7.0 7.9 12.2 13.6 13.1 21.6 17.6 20.8 12.4 12.1 13.9 18.0 12.8 16.4 15.7 14.1 15.5 15.7 22.6 15.4 94.3 118.6 136.1 2.6 54.9 194.5 354.2 317.7 306.7 1.3 61.3 75.8 0.9 45.8 150.9 58.8 0.0 291.9 50.1 432.7 70.5 285.8 7.9 107.7 65.8 83.0 77.5 155.5 2.1 559.2 1118.2 109.7 153.4 204.4 67.2 110.8 39.3 55.9 276.8 0.0 1.9 190.5 101.7 65.6 121.7 8.4 68.0 163.3 46.2 2.8 265.5 2.8 6.2 1.0 1.4 465.6 330.2 40.6 71.0 206.3 234.1 137.1 51.9 0.6 39.5 84.3 258.2 9.0 65.5 530.8 183.1 161.6 77.6 46.1 187.9 293.4 UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm NA NA 14000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.21e-2)" 98.4 157.9 102.9 98.3 113.2 94.3 98.6 103.4 115.5 127.9 133.9 101.1 71.3 127.1 64.3 155.3 119.3 64.9 117.4 106.2 102.0 131.2 114.7 109.5 105.0 106.9 104.2 136.5 89.0 107.5 135.2 67.4 109.3 103.2 68.5 95.6 119.5 78.9 201.1 119.5 100.4 117.4 94.4 131.9 98.6 98.7 110.0 119.7 160.1 114.1 110.8 101.1 124.8 121.3 269.1 273.2 307.7 471.9 207.4 186.8 135.0 175.1 187.1 248.6 200.5 219.3 201.3 201.6 111.8 357.0 361.5 254.9 392.9 375.7 180.9 163.4 391.7 126.1 295.2 180.0 145.1 215.2 258.8 177.4 193.2 362.7 279.4 176.7 330.2 236.1 138.9 173.7 250.4 343.4 203.3 188.5 329.6 163.2 417.1 233.1 215.3 343.7 198.7 287.0 197.4 148.1 520.8 250.9 116.9 329.9 349.5 130.3 241.6 183.1 210.7 266.4 166.1 117.6 132.8 286.3 189.4 150.8 224.9 31.0 39.7 40.7 39.4 51.1 34.0 39.8 31.8 35.0 43.2 29.9 24.7 31.1 44.8 38.1 49.7 29.3 40.3 39.9 102.9 113.2 103.4 115.5 106.2 102.0 106.9 104.2 109.3 94.4 110.0 121.3 37.2 51.3 34.7 45.1 37.1 33.6 38.6 55.7 26.2 24.9 48.3 39.6 51.4 51.5 50.0 82.8 16.7 46.3 34.2 133.1 35.2 77.5 29.6 84.9 56.3 40.9 57.5 33.2 27.1 90.8 68.7 45.0 74.9 97.5 18.3 60.3 43.5 51.2 60.0 11.8 35.5 78.6 30.5 49.0 37.8 61.6 42.3 51.4 19.6 31.9 57.7 20.7 13.4 32.2 46.5 147.9 74.7 65.8 44.0 55.2 82.2 61.6 56.4 25.1 39.5 38.8 56.6 10.5 34.0 51.3 42.1 71.1 34.6 56.8 68.2 55.4 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138916-157269370 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favorable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 25.7 17.4 12.0 21.5 13.2 16.2 21.7 17.5 14.1 18.4 18.8 22.3 20.0 19.4 13.4 28.3 18.5 19.1 28.5 13.2 14.1 20.3 22.9 19.0 20.9 14.6 13.4 20.0 22.4 36.2 11.1 17.5 14.9 19.9 23.2 20.2 22.7 22.7 65.6 20.8 20.8 29.2 12.7 18.0 20.9 26.2 14.8 18.6 17.3 58.5 22.8 28.1 17.0 15.0 68.8 53.3 33.5 67.3 58.8 61.3 37.1 74.0 63.4 61.1 61.3 48.3 55.7 36.8 64.0 82.1 79.6 42.4 52.6 68.3 72.0 67.6 48.3 37.6 35.6 35.0 58.4 56.9 52.8 54.8 61.6 68.0 55.9 46.4 72.2 30.3 55.7 39.9 87.6 59.8 56.2 35.9 53.3 61.1 63.6 31.9 37.7 75.9 63.2 74.1 53.5 55.2 72.8 61.9 54.5 37.2 32.0 39.3 65.3 76.6 16.5 190.0 93.3 39.7 42.9 37.0 87.7 83.0 89.5 0.3 1.8 1.1 2.2 2.3 3.0 1.1 2.4 2.4 2.0 1.2 2.2 2.7 0.6 2.1 2.5 1.8 2.8 1.5 12.0 13.2 17.5 14.1 13.2 14.1 14.6 13.4 14.9 12.7 14.8 15.0 23.8 22.4 19.7 52.2 14.2 27.5 17.3 19.0 17.6 34.7 22.4 16.9 33.7 22.8 14.2 25.8 66.7 14.9 25.3 27.3 9.8 20.3 11.6 21.6 27.4 23.4 24.5 14.9 98.9 17.7 17.4 19.6 27.0 24.5 9.5 23.0 23.6 48.3 15.4 32.0 100.7 21.8 12.2 27.6 15.2 10.1 15.5 20.6 5.4 52.5 22.0 9.9 26.8 81.4 96.2 27.5 13.4 25.6 17.5 31.5 20.6 19.1 19.8 39.9 0.0 23.1 21.4 26.6 27.3 37.5 33.2 15.1 20.9 22.3 26.2 28.1 UBQLN4 "A1U, C1orf6, UBIN" ENSG00000160803 "Ubiquilin 4" Q9NRR5 1 156035299-156053798 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061797 Approved Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA061797: AB_2684613" "unprognostic (3.91e-2)" "unprognostic (2.01e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-3)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.48e-2)" "unprognostic (1.53e-1)" "unprognostic (1.32e-2)" "unprognostic (1.91e-2)" "unprognostic (1.01e-2)" "unprognostic (2.54e-2)" "unprognostic (7.25e-3)" "unprognostic (7.65e-2)" "unprognostic (4.73e-1)" "unprognostic (1.57e-1)" 18.9 19.4 39.9 14.6 47.9 9.1 19.1 34.3 52.5 31.6 27.3 24.5 13.6 24.3 15.3 33.7 26.7 11.5 26.7 40.8 40.2 25.7 31.7 20.8 15.0 38.1 38.3 21.1 32.2 25.6 11.3 15.5 37.7 25.4 15.5 18.3 23.3 19.6 59.7 27.0 18.8 22.9 37.1 20.2 28.2 19.8 40.0 14.1 17.7 39.5 17.0 26.1 26.0 39.8 45.9 54.1 50.8 50.1 34.1 21.0 50.0 37.8 20.7 37.2 27.8 49.0 40.5 77.7 33.9 34.7 20.1 50.2 51.8 40.8 35.2 65.9 54.9 42.8 31.5 47.7 21.9 46.4 77.3 15.9 51.6 51.3 41.5 32.6 44.8 24.4 81.4 42.1 34.0 56.3 51.4 46.5 69.8 117.2 49.8 64.8 37.4 76.9 30.2 45.7 37.3 108.0 38.0 93.2 38.7 49.0 90.1 50.4 43.7 34.3 44.9 35.3 41.4 92.7 79.4 83.2 21.0 45.9 49.1 9.7 0.7 0.4 1.5 0.7 1.9 1.1 1.1 1.6 0.5 0.8 0.8 1.2 0.0 1.2 0.1 1.2 1.0 0.7 39.9 47.9 34.3 52.5 40.8 40.2 38.1 38.3 37.7 37.1 40.0 39.8 8.6 6.4 5.3 9.8 8.4 13.4 9.4 9.1 18.2 6.8 17.2 9.9 4.3 17.2 8.5 23.9 6.2 8.1 8.1 9.6 3.9 11.6 0.8 5.0 10.2 9.3 10.7 6.3 5.9 10.9 9.1 7.4 7.1 8.9 1.3 13.4 11.7 22.7 9.9 6.7 6.6 10.8 8.2 8.4 7.2 4.9 6.5 8.3 17.8 9.4 15.6 7.3 5.2 4.5 9.2 13.1 6.9 9.1 13.0 25.3 8.2 12.1 5.4 6.0 0.0 10.7 7.8 4.9 5.6 21.0 14.6 8.2 7.7 4.8 15.0 14.3 UEVLD "Attp, UEV3" ENSG00000151116 "UEV and lactate/malate dehyrogenase domains" Q8IX04 11 18529609-18588747 "Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047134 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA047134: AB_10960698" "unprognostic (1.05e-1)" "unprognostic (6.76e-2)" "prognostic favorable (7.07e-4)" "unprognostic (5.94e-3)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.38e-3)" "unprognostic (9.08e-3)" "unprognostic (9.81e-2)" "unprognostic (2.87e-2)" "unprognostic (1.26e-3)" "unprognostic (1.71e-2)" "unprognostic (1.61e-3)" "unprognostic (2.65e-1)" "unprognostic (3.22e-1)" "unprognostic (8.23e-2)" "unprognostic (3.39e-1)" 10.1 8.4 5.3 8.8 7.9 4.5 11.8 6.5 6.7 11.5 6.3 13.4 11.1 8.8 8.7 10.7 8.8 9.4 9.2 5.7 6.4 12.3 9.0 9.0 7.0 8.1 7.1 8.0 7.2 9.9 4.2 9.4 8.5 10.4 14.1 9.7 7.5 9.5 11.0 14.8 10.0 11.0 6.6 6.9 9.8 5.3 7.0 7.6 10.9 10.5 8.6 10.2 6.9 11.1 16.2 19.6 8.9 8.6 28.2 25.1 8.3 17.5 24.3 22.7 21.6 8.1 4.6 5.0 9.4 20.7 19.8 24.8 8.2 18.1 25.8 14.6 10.7 7.5 8.8 9.1 12.7 11.5 10.4 17.4 18.3 11.2 15.5 15.9 21.2 0.4 5.7 4.7 29.3 12.3 0.3 3.7 2.4 24.9 19.8 1.8 20.7 6.2 26.9 25.4 3.7 7.9 19.1 23.8 15.1 11.0 19.1 6.8 16.2 20.7 11.1 34.0 17.2 0.9 11.3 1.1 17.7 8.7 21.3 4.6 4.9 3.1 4.2 5.1 4.0 2.6 3.1 3.5 3.4 2.7 1.8 2.6 6.5 5.2 4.2 4.2 2.3 2.4 5.3 7.9 6.5 6.7 5.7 6.4 8.1 7.1 8.5 6.6 7.0 11.1 10.3 16.0 19.3 18.9 4.5 6.2 6.3 9.9 8.6 9.3 11.2 6.3 10.1 5.7 12.4 23.9 10.4 8.4 9.4 27.3 3.9 10.8 3.3 13.6 12.4 11.6 9.1 4.8 14.7 13.3 7.4 8.7 10.7 12.9 6.3 11.6 13.6 13.5 12.5 15.2 14.4 15.4 18.3 18.6 10.3 2.0 8.1 11.0 7.2 20.6 11.9 13.3 11.3 25.1 34.3 14.5 10.3 18.4 3.4 8.3 12.8 12.8 23.9 11.1 13.1 10.2 8.7 7.1 7.2 10.1 9.2 7.7 6.6 11.7 15.7 7.6 UGT2B17 ENSG00000197888 "UDP glucuronosyltransferase family 2 member B17" O75795 4 68537184-68568527 "Enzymes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 460.0;liver: 136.2" "Group enriched" "Detected in some" 6 "Distal enterocytes: 130.1;Paneth cells: 35.1;Undifferentiated cells: 100.6" "Group enriched" "Detected in many" 7 "colorectal cancer: 16.3;liver cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 2.8;naive B-cell: 8.8" "Lineage enriched" "Detected in single" 61 "B-cells: 8.8" "Cell line enhanced" "Detected in some" "BEWO: 1.0;NB-4: 1.1;RPMI-8226: 1.7" HPA045108 Supported NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA045108: AB_2679218" "unprognostic (1.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-2)" "unprognostic (2.41e-1)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.44e-3)" "unprognostic (9.67e-2)" "unprognostic (4.80e-3)" "unprognostic (8.52e-2)" "unprognostic (2.45e-1)" "unprognostic (6.44e-2)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" 0.3 0.0 0.0 38.8 0.0 0.0 0.7 0.0 0.0 1.5 0.0 365.7 364.3 1.4 1.5 0.1 0.2 0.6 0.0 0.0 0.0 0.2 136.2 0.2 1.5 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 125.8 0.0 0.2 0.7 0.0 0.0 460.0 9.1 0.1 0.6 0.8 0.0 0.1 0.4 0.0 0.0 2.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.1 0.0 0.0 1.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.0 130.1 0.0 0.0 0.0 11.1 0.1 0.0 1.8 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.4 2.8 0.0 0.0 0.1 13.8 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.3 0.1 35.1 0.0 1.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 100.6 0.2 UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108736 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 250.1;Extravillous trophoblasts: 260.3;Macrophages: 199.5;Paneth cells: 260.8" "Cancer enhanced" "Detected in all" "testis cancer: 62.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "hTERT-HME1: 362.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm No No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA054040: AB_2682352, HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" 16.4 9.4 3.8 7.5 4.4 12.5 10.0 3.0 5.8 16.8 2.0 9.8 4.3 3.9 0.8 66.9 5.7 5.9 8.9 3.1 3.9 39.8 11.9 18.8 3.7 4.2 2.8 1.9 4.6 5.0 7.4 3.8 3.7 4.9 5.3 0.5 14.2 1.1 3.7 3.1 6.5 3.4 1.3 20.3 4.1 2.2 4.4 1.2 8.0 0.9 6.6 9.1 31.2 3.7 19.5 26.0 2.4 5.2 8.9 4.0 29.7 7.9 15.5 14.5 17.5 10.8 9.9 0.0 2.5 9.7 89.9 13.9 5.2 46.1 9.4 4.1 4.5 0.8 4.8 4.6 7.4 0.9 1.3 5.0 21.8 6.4 362.8 5.9 9.1 0.4 1.5 13.5 7.6 2.3 0.0 2.9 9.4 4.2 20.7 0.0 4.8 6.0 33.7 11.5 2.3 1.6 10.2 3.0 63.4 29.3 2.4 0.9 12.4 29.6 22.9 7.3 22.6 21.4 34.7 3.7 29.6 3.0 77.8 11.5 16.0 12.2 11.8 12.1 8.9 0.2 7.8 8.7 6.5 0.6 8.1 8.1 6.2 5.4 14.8 0.5 8.4 10.9 3.8 4.4 3.0 5.8 3.1 3.9 4.2 2.8 3.7 1.3 4.4 3.7 107.4 19.2 58.5 5.2 19.1 46.8 26.3 104.4 19.4 27.6 9.0 16.1 11.6 24.3 51.0 11.0 33.3 15.1 122.9 250.1 70.5 50.5 1.0 42.1 22.4 108.1 13.1 4.4 16.5 40.5 260.3 34.1 5.1 91.1 25.9 3.8 72.5 17.5 110.0 16.8 29.4 35.0 85.5 130.5 118.1 2.4 5.3 199.5 87.2 1.0 61.4 13.3 71.1 4.0 3.6 117.9 260.8 2.2 30.3 30.4 42.8 23.3 11.9 29.2 6.6 21.1 32.2 0.3 9.5 42.9 29.8 78.7 71.0 1.5 29.1 34.9 URGCP "DKFZp666G166, DKFZp686O0457, FLJ20654, KIAA1507, URG4" ENSG00000106608 "Upregulator of cell proliferation" Q8TCY9 7 43875894-43926411 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019879, HPA020134, HPA029468" Approved Supported Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA019879: AB_1858651, HPA020134: AB_1858652, HPA029468: AB_10601831" "unprognostic (5.66e-2)" "unprognostic (1.10e-3)" "unprognostic (1.18e-1)" "unprognostic (2.75e-1)" "unprognostic (2.21e-3)" "unprognostic (2.42e-2)" "unprognostic (3.74e-2)" "unprognostic (1.26e-1)" "unprognostic (3.79e-1)" "unprognostic (2.21e-1)" "unprognostic (3.23e-3)" "unprognostic (3.71e-1)" "prognostic favorable (1.90e-4)" "unprognostic (1.56e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (1.69e-3)" 15.9 35.6 25.1 9.9 24.6 10.3 15.0 24.5 25.9 19.7 24.1 22.6 24.3 17.7 14.7 17.8 19.5 11.1 25.2 24.5 22.5 24.3 29.6 14.2 10.8 20.7 20.0 20.7 19.1 22.1 27.4 11.9 21.3 21.6 19.0 20.1 15.6 16.1 34.9 18.6 22.8 18.7 19.2 18.5 17.4 9.7 23.4 10.4 18.7 31.6 10.6 20.4 16.6 23.8 28.2 25.1 10.1 32.1 26.3 24.0 9.6 33.2 58.4 35.2 35.6 21.1 21.8 16.5 16.9 31.7 53.5 44.3 28.0 23.8 34.3 31.6 17.3 11.5 25.2 19.0 28.0 17.7 20.3 18.5 28.5 27.8 27.0 23.1 17.7 18.9 28.6 13.1 23.7 21.0 18.6 14.6 19.1 33.1 25.8 24.9 14.6 22.2 33.7 27.7 25.8 44.4 34.4 49.6 15.4 16.5 25.0 21.0 19.5 20.3 9.4 22.8 26.1 34.1 53.6 20.7 23.2 26.7 38.6 4.5 4.7 6.2 8.8 7.4 9.4 5.8 9.2 11.7 10.2 4.9 9.9 8.8 0.5 2.8 8.3 1.6 10.6 6.6 25.1 24.6 24.5 25.9 24.5 22.5 20.7 20.0 21.3 19.2 23.4 23.8 10.1 3.2 9.2 14.7 12.2 11.1 13.4 7.9 9.1 25.9 17.7 17.8 23.8 12.8 7.3 12.9 8.4 6.3 8.9 41.0 17.6 13.0 1.2 16.3 14.3 10.2 8.4 6.3 28.6 13.2 11.8 13.5 23.9 23.2 7.0 21.1 12.5 27.3 6.5 16.8 25.1 12.5 10.2 5.0 10.2 3.4 18.3 7.5 12.4 6.5 4.8 12.2 7.2 7.5 17.6 15.7 23.4 18.8 4.2 14.1 37.9 26.4 8.7 20.4 6.6 13.8 12.6 8.8 8.3 9.1 14.8 3.4 10.8 15.2 16.2 15.0 VARS2 "DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL" ENSG00000137411 "Valyl-tRNA synthetase 2, mitochondrial" Q5ST30 6 30914205-30926459 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062449, HPA070267" Approved Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA062449: AB_2684766, HPA070267: AB_2686245" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "unprognostic (1.96e-3)" "unprognostic (2.50e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-2)" "unprognostic (3.14e-1)" "unprognostic (8.98e-2)" "unprognostic (4.23e-2)" "unprognostic (2.60e-2)" "unprognostic (2.15e-3)" "unprognostic (1.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.19e-2)" "unprognostic (2.43e-2)" 10.2 14.4 1.3 2.1 1.5 1.9 9.7 1.5 1.6 12.5 0.4 10.5 1.2 10.4 1.5 22.5 10.1 0.2 11.1 1.4 1.3 12.5 18.9 10.5 3.1 1.3 1.6 15.3 14.0 2.3 17.1 0.9 1.4 10.2 2.2 1.4 10.9 1.1 20.9 10.1 12.8 0.7 1.2 13.4 11.7 11.8 1.3 4.1 15.0 0.2 2.3 10.5 13.2 1.3 13.8 9.6 5.5 23.1 4.9 4.4 0.7 2.2 1.9 2.5 1.6 12.6 8.9 11.9 7.5 3.0 9.4 0.0 21.3 0.0 2.4 4.6 15.7 13.2 10.2 0.9 6.7 2.3 0.3 6.2 8.1 5.9 1.3 0.9 1.3 19.5 0.1 10.5 5.4 0.0 4.6 0.0 1.7 0.0 1.2 9.1 0.0 10.3 18.3 0.0 8.5 0.2 0.2 6.6 5.4 5.0 16.3 7.4 2.2 14.2 1.4 1.0 0.1 10.0 17.1 18.8 0.0 0.6 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.3 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.3 0.2 0.1 1.3 1.5 1.5 1.6 1.4 1.3 1.3 1.6 1.4 1.2 1.3 1.3 3.0 6.4 12.5 14.7 8.0 4.0 4.9 4.7 4.0 6.6 6.4 3.7 11.6 8.6 5.5 9.2 0.0 8.7 4.1 10.1 1.9 6.7 1.5 7.7 5.2 3.9 13.1 3.4 8.3 7.1 9.6 4.8 11.7 8.6 12.7 12.9 7.5 22.5 9.2 8.4 9.1 8.4 2.0 6.9 3.5 1.6 4.1 5.1 1.8 3.7 7.9 2.8 4.1 8.0 7.2 8.9 4.7 4.1 12.3 2.3 12.4 12.5 8.9 6.0 0.0 2.9 3.7 10.4 8.0 9.0 4.1 3.4 4.8 6.9 10.9 3.8 VDR "NR1I1, PPP1R163" ENSG00000111424 "Vitamin D receptor" P11473 12 47841537-47943048 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 235.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 141.7;Proximal enterocytes: 88.7;Undifferentiated cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "classical monocyte: 3.5;eosinophil: 1.9;intermediate monocyte: 6.5;myeloid DC: 5.1;neutrophil: 6.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 8 "dendritic cells: 5.1;granulocytes: 6.5;monocytes: 6.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 55.5;HDLM-2: 80.0;U-937: 85.3" "Region enhanced" "Detected in single" "olfactory bulb: 2.1" "Region enhanced" "Detected in some" "spinal cord: 4.3" "CAB004617, HPA047740, HPA072102" Supported "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments, Cytosol" "CAB004617: AB_628040, HPA047740: AB_2680142, HPA072102: " "unprognostic (1.11e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (7.59e-3)" "unprognostic (3.33e-3)" "unprognostic (2.74e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (6.72e-2)" "prognostic favorable (4.89e-6)" "unprognostic (1.46e-1)" "unprognostic (8.76e-2)" "unprognostic (3.28e-1)" "unprognostic (3.82e-2)" 3.6 13.7 0.2 13.3 0.2 8.2 11.3 0.2 0.4 5.0 0.9 40.4 56.0 1.6 0.4 13.6 1.8 8.5 1.2 0.2 0.7 21.0 1.1 7.7 5.3 0.7 0.4 0.5 2.1 235.9 11.1 2.9 0.6 1.9 35.3 0.2 6.1 1.8 2.8 22.1 55.0 3.8 0.1 2.6 7.4 1.0 1.4 1.5 2.2 0.6 7.2 10.4 7.6 0.3 15.0 2.6 0.1 0.1 12.0 16.4 0.2 17.7 8.6 15.0 12.9 10.6 12.1 3.5 17.4 13.6 10.7 27.1 0.5 55.5 6.4 80.0 4.0 6.3 3.1 0.9 8.1 12.2 20.3 23.6 30.5 16.4 26.0 22.3 1.2 1.3 1.8 3.9 7.0 9.2 0.3 6.0 0.2 34.8 19.1 0.3 0.0 9.9 13.3 13.5 6.2 0.2 14.7 42.6 5.9 0.1 47.6 6.7 1.0 28.8 7.3 8.2 10.2 2.2 0.1 3.0 8.6 85.3 7.7 0.1 3.5 1.9 0.0 6.5 0.1 0.5 0.3 0.0 5.1 0.0 0.1 0.0 6.5 0.2 6.7 0.4 0.7 1.5 0.2 0.2 0.2 0.4 0.2 0.7 0.7 0.4 0.6 0.1 1.4 0.3 0.4 12.8 20.1 0.3 1.4 36.1 9.0 8.5 24.5 0.5 21.2 13.7 1.7 0.0 9.2 7.3 0.0 0.2 0.9 141.7 7.9 3.5 0.2 11.9 0.5 1.3 21.7 0.0 0.4 10.9 0.1 5.3 14.3 4.7 7.0 0.2 0.0 0.3 3.4 0.0 0.3 32.8 2.0 7.3 43.4 0.0 0.0 21.2 8.8 1.0 10.4 0.2 0.0 0.5 0.1 22.4 43.3 0.4 10.9 8.3 88.7 32.0 9.0 0.2 0.0 1.1 2.2 0.7 0.3 23.4 40.6 0.3 2.8 0.0 72.4 11.6 VILL ENSG00000136059 "Villin like" O15195 3 37988059-38007188 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 61.9;stomach 1: 97.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 221.7;Gastric mucus-secreting cells: 192.7;Paneth cells: 139.0;Proximal enterocytes: 165.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.0;OE19: 78.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA035675, HPA035676" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA035675: AB_10671223, HPA035676: " "unprognostic (7.86e-3)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (1.35e-4)" "prognostic favorable (1.75e-4)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.95e-2)" "unprognostic (3.66e-3)" "unprognostic (5.55e-2)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (7.43e-3)" 5.4 3.7 8.7 11.0 9.0 12.6 6.4 6.6 10.6 9.5 6.4 46.8 61.9 5.7 1.5 7.2 6.7 15.7 6.4 8.6 7.8 5.3 1.4 7.7 9.8 8.3 8.4 6.8 3.4 1.2 5.1 4.1 8.0 16.0 26.6 1.2 5.7 4.0 1.2 9.1 61.7 4.1 8.0 11.8 97.5 5.4 8.2 10.2 7.4 1.4 6.3 17.5 7.4 7.2 8.2 0.1 0.2 0.4 2.8 2.2 0.8 2.3 1.9 2.3 2.2 6.1 25.0 3.9 3.5 1.6 0.0 1.9 1.8 0.2 0.5 0.8 0.0 7.3 0.1 0.6 3.4 7.7 9.5 3.3 2.2 2.2 0.0 0.0 4.5 16.1 7.3 2.3 2.6 0.1 12.4 8.7 0.2 78.4 0.0 4.8 0.0 2.0 0.8 9.8 0.1 0.3 0.0 0.5 1.8 0.0 0.7 12.4 2.8 1.0 0.3 3.0 0.0 1.4 3.1 1.2 0.6 10.9 5.0 0.0 3.2 0.0 6.8 2.0 7.4 3.5 4.4 3.9 2.1 4.6 5.6 4.2 0.1 3.4 1.4 3.8 5.8 4.1 8.7 9.0 6.6 10.6 8.6 7.8 8.3 8.4 8.0 8.0 8.2 7.2 4.9 9.6 7.4 10.4 7.2 2.3 5.7 25.5 6.8 0.9 3.3 2.9 1.9 8.6 46.1 0.0 0.0 3.0 13.3 221.7 0.0 3.4 6.2 1.5 2.7 4.5 9.6 6.1 5.5 16.9 3.4 6.7 192.7 1.5 8.2 6.1 5.3 0.3 2.4 1.7 3.0 64.4 14.2 1.9 2.4 19.9 3.7 4.0 1.8 3.7 4.2 28.1 7.2 2.5 1.2 38.7 139.0 2.6 4.4 6.2 165.6 1.6 40.5 0.8 0.0 4.3 7.1 5.4 3.4 3.1 1.4 1.0 8.1 5.6 50.5 33.4 VIPR1 "HVR1, RDC1, VPAC1, VPAC1R" ENSG00000114812 "Vasoactive intestinal peptide receptor 1" P32241 3 42489299-42537573 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 132.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 71.8;Intestinal goblet cells: 48.6;Paneth cells: 96.2;Proximal enterocytes: 58.6" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "dendritic cells: 2.1;monocytes: 1.8;T-cells: 2.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 60.8;OE19: 36.2;RT4: 44.0;SK-BR-3: 24.7;WM-115: 79.0" "Group enriched" "Detected in many" 4 "amygdala: 6.3;basal ganglia: 4.5;cerebral cortex: 9.6;hippocampal formation: 7.7;white matter: 2.5" "Low region specificity" "Detected in all" HPA026777 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA026777: AB_10604003" "unprognostic (9.02e-2)" "unprognostic (9.34e-3)" "unprognostic (3.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (8.89e-4)" "unprognostic (4.00e-3)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.28e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-3)" "unprognostic (7.70e-2)" "unprognostic (1.69e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-2)" 17.5 2.6 10.1 3.4 12.7 2.3 16.9 13.5 15.2 2.9 5.1 28.0 34.5 1.2 6.6 5.3 1.3 6.0 6.5 13.0 5.5 2.7 32.4 132.1 4.6 5.3 4.8 0.6 2.5 4.2 1.9 2.8 6.3 25.0 27.7 4.2 22.7 8.9 1.2 29.8 30.0 1.3 4.4 5.7 6.1 1.4 4.7 1.9 15.1 4.9 2.4 8.7 5.0 12.1 0.1 2.4 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.4 2.2 60.8 0.2 3.1 0.0 0.0 2.4 0.0 1.6 0.1 0.0 5.2 3.8 1.8 0.0 0.3 0.0 0.5 0.0 3.8 0.2 1.2 0.0 0.7 0.6 0.0 0.0 0.0 5.2 0.0 0.3 3.8 36.2 0.2 0.5 0.0 2.8 0.0 44.0 1.3 0.0 0.0 24.7 0.0 7.1 15.2 0.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 79.0 0.0 1.8 0.0 0.2 1.5 1.0 0.0 2.4 1.0 2.1 0.0 2.7 0.8 0.0 0.0 1.3 0.0 0.4 0.9 10.1 12.7 13.5 15.2 13.0 5.5 5.3 4.8 6.3 4.4 4.7 12.1 16.0 3.2 6.0 3.3 1.3 7.6 4.5 2.2 22.2 0.2 19.2 21.5 2.6 5.7 2.1 1.8 8.4 0.1 0.4 71.8 0.0 0.3 3.0 0.2 0.1 2.8 4.8 0.0 26.9 0.9 1.0 1.0 16.3 0.6 0.0 0.3 19.6 0.4 0.7 0.0 1.5 48.6 0.0 8.7 4.0 0.6 0.0 5.9 0.0 3.7 8.9 1.4 0.0 3.0 1.7 1.2 96.2 0.0 1.5 6.3 58.6 0.1 1.0 5.4 32.9 0.2 20.8 0.1 0.1 4.1 7.7 0.3 2.9 0.1 24.0 3.9 VPS28 ENSG00000160948 "VPS28 subunit of ESCRT-I" Q9UK41 8 144423601-144428563 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;SH-SY5Y: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024688, HPA024745" Supported NA NA 63000 "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA024688: AB_1858766, HPA024745: AB_1858765" "unprognostic (2.87e-2)" "unprognostic (1.87e-1)" "unprognostic (1.27e-1)" "prognostic favorable (9.93e-4)" "unprognostic (3.18e-1)" "unprognostic (2.03e-1)" "unprognostic (9.29e-2)" "unprognostic (7.94e-3)" "unprognostic (1.54e-2)" "unprognostic (2.00e-2)" "unprognostic (7.92e-2)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (2.93e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (2.37e-2)" 132.8 137.6 0.1 0.0 0.1 0.0 132.9 0.0 0.3 147.7 0.0 150.5 0.0 133.7 0.0 138.0 127.3 0.1 177.5 0.1 0.2 173.8 162.7 123.1 0.1 0.1 0.2 159.6 146.5 0.0 129.3 0.1 0.5 136.3 0.0 0.7 119.7 0.2 197.7 150.4 140.0 0.0 0.0 144.9 154.1 151.8 0.1 0.0 144.5 1.1 0.0 128.7 135.4 0.2 0.2 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.2 0.1 0.2 0.5 0.0 0.1 0.2 189.6 112.2 128.6 32.3 126.9 103.2 138.6 180.0 105.9 91.9 139.0 171.2 70.1 131.5 133.9 169.2 60.5 166.4 126.6 387.2 273.9 264.5 208.6 130.4 131.5 149.7 172.7 139.3 20.1 251.1 160.9 142.9 154.9 164.9 185.5 191.5 142.1 141.4 250.7 57.2 25.9 256.8 128.1 178.9 155.9 183.1 198.8 172.1 188.5 22.5 285.8 168.6 144.1 20.1 32.3 287.3 462.2 156.1 112.8 128.9 561.9 526.5 134.6 121.8 157.8 140.0 206.5 232.1 127.2 142.7 133.5 112.7 160.9 275.7 206.0 168.8 VSIG10 ENSG00000176834 "V-set and immunoglobulin domain containing 10" Q8N0Z9 12 118063593-118136026 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.3;Proximal enterocytes: 106.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 33.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062022 Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Centriolar satellite" "HPA062022: AB_2732675" "unprognostic (1.32e-1)" "unprognostic (7.76e-2)" "unprognostic (2.05e-1)" "unprognostic (4.62e-3)" "unprognostic (1.09e-1)" "unprognostic (6.42e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.53e-4)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (1.75e-1)" "unprognostic (2.85e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.48e-2)" 6.1 11.3 4.5 2.3 5.5 0.8 6.0 5.4 4.6 6.8 4.8 13.3 13.9 4.3 3.1 8.7 4.7 3.8 3.8 3.9 4.5 6.2 5.7 8.4 1.5 6.0 4.9 6.4 7.1 8.1 4.4 8.6 4.9 5.9 15.8 1.9 7.0 5.2 17.0 5.6 24.5 3.2 5.4 3.9 6.5 2.6 5.3 0.9 12.1 10.8 2.1 5.9 6.9 4.8 7.9 11.4 4.8 16.1 19.4 8.8 12.4 13.3 8.5 6.4 5.3 3.3 18.2 1.1 5.3 9.8 12.0 18.9 33.8 3.4 7.6 4.0 5.1 1.8 11.0 5.0 3.9 1.1 2.7 4.0 9.8 4.9 3.1 18.6 14.2 3.8 2.3 0.1 6.1 8.3 0.0 1.1 14.9 22.8 7.5 2.8 13.2 0.0 9.4 25.1 4.1 5.3 13.0 5.4 3.4 10.2 11.9 5.3 16.8 7.4 4.7 9.2 6.8 0.1 0.1 0.1 10.7 5.5 15.0 0.2 0.5 0.6 0.1 0.1 0.1 0.0 0.1 0.0 0.6 0.1 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.1 4.5 5.5 5.4 4.6 3.9 4.5 6.0 4.9 4.9 5.4 5.3 4.8 23.6 19.2 28.6 14.0 3.3 2.4 13.0 1.8 6.8 9.9 15.1 11.7 11.4 31.5 5.0 29.5 12.5 38.0 2.2 69.3 19.6 26.2 6.1 10.3 13.0 19.1 50.4 9.9 4.7 20.3 41.0 11.9 16.8 13.6 2.5 33.3 21.0 27.5 11.2 5.0 5.1 40.4 2.0 6.7 9.4 9.9 18.0 5.6 3.6 3.7 7.4 18.9 2.1 9.0 3.1 26.7 45.3 14.7 3.1 10.4 106.6 13.7 2.7 7.9 0.0 12.9 8.6 4.0 6.1 12.4 3.1 14.0 4.0 24.7 48.2 15.3 VSIG2 "CTH, CTXL" ENSG00000019102 "V-set and immunoglobulin domain containing 2" Q96IQ7 11 124747474-124752255 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "stomach 1: 619.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 514.3;Gastric mucus-secreting cells: 623.4;Intestinal goblet cells: 285.6;Pancreatic endocrine cells: 260.2;Paneth cells: 509.9;Undifferentiated cells: 207.0;Urothelial cells: 285.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 87.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 6 "OE19: 429.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035919, HPA050147" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 39: Non-specific - mRNA processing" "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA035919: AB_10669981, HPA050147: AB_2681032" "unprognostic (1.64e-3)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-1)" "unprognostic (2.18e-3)" "unprognostic (2.16e-1)" "unprognostic (2.22e-2)" "unprognostic (3.47e-3)" "unprognostic (2.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-2)" "unprognostic (2.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-2)" 6.5 0.8 3.1 7.0 6.4 3.4 9.5 0.8 7.1 29.7 0.2 136.2 6.2 4.9 0.4 26.4 17.5 26.5 5.3 2.8 1.5 6.3 3.0 45.7 0.9 1.7 3.6 1.1 2.0 1.9 1.7 6.0 2.0 58.2 137.8 0.6 31.8 4.3 2.3 1.5 2.8 4.7 1.1 1.6 619.2 0.9 3.1 0.2 43.7 2.5 2.5 84.5 9.3 3.6 0.4 0.1 4.8 3.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.9 1.5 2.4 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.3 16.6 0.0 7.9 0.7 0.5 3.0 0.1 0.0 0.0 0.0 0.3 2.8 0.3 0.3 0.6 0.0 1.6 0.1 0.1 0.6 429.0 3.7 0.4 3.6 0.1 0.1 69.2 0.3 0.9 0.1 4.6 0.0 0.7 0.4 2.4 4.1 1.8 1.1 0.3 0.8 0.3 0.0 0.0 0.6 1.7 0.9 0.0 1.2 0.0 0.0 0.1 0.5 0.0 0.5 0.1 0.4 0.0 0.6 0.4 0.1 0.3 0.2 0.0 0.7 0.9 3.1 6.4 0.8 7.1 2.8 1.5 1.7 3.6 2.0 1.1 3.1 3.6 4.6 125.0 51.6 0.0 1.5 0.8 19.2 25.3 2.8 1.5 31.5 18.4 0.7 82.9 99.3 3.7 0.0 0.0 0.6 514.3 1.9 14.6 0.0 12.1 1.8 5.0 66.8 0.0 0.2 90.9 0.1 0.9 623.4 18.3 1.3 0.1 3.9 0.2 0.1 0.0 0.1 285.6 20.3 0.3 2.7 0.0 1.5 2.4 3.6 1.0 0.0 0.0 0.0 0.0 0.1 260.2 509.9 0.0 0.7 61.6 1.3 0.1 36.7 0.0 0.0 0.3 6.2 0.2 0.7 0.7 0.4 0.0 2.2 0.3 207.0 285.3 WASL "N-WASP, NWASP, WASPB" ENSG00000106299 "WASP like actin nucleation promoting factor" O00401 7 123681943-123749003 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 282.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 138.3;U-2197: 128.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005399, HPA005750" Supported Approved Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoli "CAB005399: AB_2288632, HPA005750: AB_1854729" "unprognostic (1.91e-1)" "unprognostic (3.60e-2)" "unprognostic (8.19e-2)" "unprognostic (1.83e-1)" "unprognostic (3.20e-1)" "unprognostic (4.61e-2)" "unprognostic (4.08e-2)" "unprognostic (1.95e-1)" "unprognostic (1.30e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.30e-5)" "unprognostic (7.32e-2)" "prognostic favorable (4.51e-8)" "unprognostic (9.49e-2)" "unprognostic (2.30e-1)" "unprognostic (3.81e-1)" "unprognostic (5.14e-1)" 20.4 24.7 19.2 12.8 22.2 5.6 21.7 13.5 42.4 29.1 13.6 42.4 37.2 27.1 18.3 29.5 18.7 28.4 18.2 43.0 20.4 44.1 46.8 19.9 7.8 18.0 19.1 35.1 29.5 40.0 13.0 34.6 17.4 25.3 37.9 24.9 22.3 24.0 24.7 18.0 41.5 23.6 13.5 17.0 30.1 22.5 20.9 10.3 35.2 28.7 11.0 38.7 22.5 18.4 34.4 24.8 26.7 23.0 41.2 42.4 34.7 23.3 38.7 16.9 21.7 20.5 42.2 3.5 18.1 35.3 36.0 25.1 50.1 25.7 25.9 6.0 19.9 3.0 19.6 22.2 44.7 4.6 2.9 34.2 47.0 25.0 42.2 37.9 29.5 3.6 15.5 6.6 40.6 20.7 6.0 6.1 50.1 36.5 22.4 3.6 21.6 7.7 35.6 138.3 32.9 48.1 32.1 95.0 63.0 41.4 18.6 4.5 33.8 44.9 12.6 128.1 23.2 7.2 2.7 7.5 38.8 3.8 36.7 2.4 1.7 0.8 1.7 1.7 1.4 2.0 1.1 1.0 1.5 1.3 1.4 1.5 0.7 2.5 3.0 1.9 0.6 0.6 19.2 22.2 13.5 42.4 43.0 20.4 18.0 19.1 17.4 13.5 20.9 18.4 71.2 86.6 61.1 36.9 11.5 60.4 48.9 44.4 46.1 32.9 67.6 57.1 69.8 52.9 53.7 53.3 20.9 41.6 12.6 200.2 52.8 52.6 26.2 58.0 53.1 43.9 67.9 5.9 55.9 54.1 52.4 62.6 50.0 68.8 3.8 35.0 56.4 61.9 12.7 26.9 51.2 105.1 40.7 13.8 25.1 9.3 48.1 15.6 30.2 34.7 14.0 60.9 6.2 42.7 48.7 70.6 113.4 64.7 14.0 104.4 108.0 96.0 49.5 32.4 19.7 54.1 75.3 17.2 21.3 54.9 68.3 81.3 13.1 76.0 74.8 282.3 WDR55 "FLJ20195, FLJ21702" ENSG00000120314 "WD repeat domain 55" Q9H6Y2 5 140664676-140674124 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043470, HPA048143, HPA075133" Uncertain Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Nucleoli "HPA043470: AB_2678495, HPA048143: AB_2680282, HPA075133: " "prognostic unfavorable (1.51e-4)" "unprognostic (1.35e-1)" "unprognostic (7.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.88e-6)" "unprognostic (9.96e-2)" "unprognostic (2.78e-1)" "unprognostic (3.05e-1)" "unprognostic (4.00e-2)" "unprognostic (1.02e-2)" "unprognostic (1.19e-3)" "unprognostic (1.37e-1)" "unprognostic (2.14e-1)" "unprognostic (3.70e-1)" "unprognostic (2.51e-2)" 9.9 9.2 5.2 9.5 5.4 12.9 9.2 6.2 5.6 7.6 6.8 10.6 9.3 7.8 4.3 13.4 7.4 6.1 7.7 5.4 5.8 9.4 12.3 8.8 10.1 6.4 5.6 7.5 11.1 6.1 9.0 7.6 6.0 8.8 10.3 4.0 10.5 5.4 9.1 11.0 11.0 6.4 5.4 12.6 10.5 4.9 5.7 7.8 7.4 6.0 10.6 8.9 7.9 5.9 13.2 18.0 8.5 34.4 12.8 10.1 23.7 12.9 15.5 13.3 15.2 31.1 17.7 12.3 16.8 16.6 24.3 16.1 11.5 22.4 10.2 11.6 9.6 14.1 15.9 12.7 12.2 14.8 25.5 12.2 12.7 18.3 9.6 9.2 14.4 13.7 9.9 9.3 14.9 19.2 14.0 13.3 8.9 18.9 15.2 11.6 12.2 11.6 15.9 19.7 8.3 11.1 17.7 51.3 20.2 10.4 36.3 15.8 13.0 17.5 9.0 20.3 17.6 15.6 12.9 9.6 22.7 19.5 10.6 6.4 10.2 7.8 11.3 16.6 11.7 8.5 10.5 9.8 9.9 7.3 8.3 8.5 9.0 10.3 14.2 7.2 12.6 10.0 5.2 5.4 6.2 5.6 5.4 5.8 6.4 5.6 6.0 5.4 5.7 5.9 17.1 9.6 16.7 5.9 16.9 14.5 10.9 9.1 9.6 13.5 15.5 10.3 5.3 5.7 16.2 18.4 12.5 21.6 28.9 31.9 21.5 20.2 29.3 20.6 13.1 12.9 14.9 13.9 7.2 28.2 42.8 12.6 25.0 13.9 19.7 16.4 12.5 14.9 20.8 23.5 7.0 22.6 8.2 16.1 13.9 9.7 9.6 18.3 8.8 1.0 20.5 5.7 23.7 4.5 6.5 27.2 39.3 7.5 23.0 15.6 24.9 20.8 17.2 8.3 13.1 13.0 14.1 7.9 9.8 15.1 13.4 23.3 21.0 14.2 26.0 16.4 WIPF2 "WICH, WIRE" ENSG00000171475 "WAS/WASL interacting protein family member 2" Q8TF74 17 40219304-40284136 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 99.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024000, HPA024001, HPA024467" Enhanced NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA024000: AB_1858840, HPA024001: AB_1858841, HPA024467: AB_1858842" "unprognostic (1.90e-1)" "unprognostic (1.02e-1)" "unprognostic (2.59e-1)" "unprognostic (6.07e-2)" "unprognostic (2.63e-2)" "unprognostic (1.83e-1)" "unprognostic (5.18e-3)" "unprognostic (1.92e-1)" "unprognostic (2.05e-1)" "unprognostic (8.51e-3)" "unprognostic (2.05e-2)" "unprognostic (4.34e-2)" "unprognostic (1.32e-3)" "unprognostic (4.12e-1)" "unprognostic (7.51e-2)" "unprognostic (5.28e-2)" "unprognostic (9.23e-2)" 10.9 7.1 10.4 10.0 9.9 17.4 8.4 11.1 18.8 9.6 2.2 14.3 12.0 10.3 9.3 14.9 9.3 10.0 6.4 11.4 12.0 12.2 7.5 12.7 8.5 8.0 8.3 7.8 10.3 12.4 7.4 12.0 6.2 8.5 13.5 9.4 9.0 10.3 6.9 15.4 13.3 11.8 3.7 11.9 12.8 6.6 10.9 7.8 9.0 6.8 11.3 9.3 10.2 9.1 23.4 36.0 15.3 14.5 15.6 16.4 15.1 20.5 14.1 18.5 19.8 17.7 20.1 13.7 22.8 24.8 23.0 39.4 13.1 15.7 24.3 24.7 15.9 14.8 17.6 21.3 15.9 19.7 16.1 13.2 19.3 19.3 21.8 19.9 18.2 14.6 14.3 12.5 18.0 15.3 19.5 9.9 9.2 17.5 11.1 12.5 18.6 13.6 19.8 38.2 18.8 13.1 37.3 99.2 13.6 26.0 33.5 12.1 26.5 12.5 18.7 24.0 23.8 13.9 23.3 13.9 27.5 10.3 18.9 5.2 2.0 2.4 3.3 1.8 2.7 3.0 1.9 2.0 1.5 2.2 2.2 1.9 7.1 2.6 2.1 2.5 2.4 1.0 10.4 9.9 11.1 18.8 11.4 12.0 8.0 8.3 6.2 3.7 10.9 9.1 28.4 67.3 39.5 71.2 32.5 43.1 33.8 28.7 29.6 38.0 35.7 23.6 11.8 41.5 25.2 46.0 45.9 50.7 29.4 102.5 13.7 29.0 3.9 31.8 27.8 35.5 47.3 17.2 71.8 36.6 31.5 24.5 35.2 54.9 38.1 23.6 43.2 25.3 30.3 42.1 52.7 33.9 26.4 48.3 31.7 3.4 20.2 27.9 16.0 37.5 32.2 20.8 33.0 36.2 36.5 52.0 57.5 25.9 15.9 44.6 60.3 26.4 22.3 17.2 39.5 26.9 23.3 20.6 34.2 54.9 69.0 67.5 31.1 15.9 36.4 70.7 WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184916-93320572 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 83.1;skeletal muscle: 62.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cone photoreceptor cells: 160.6;Excitatory neurons: 128.5;Inhibitory neurons: 98.8;Intestinal goblet cells: 77.3;Rod photoreceptor cells: 106.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.8;Hep G2: 31.0;SCLC-21H: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB017813: , HPA015555: AB_2669218, HPA016519: AB_2669380" "unprognostic (5.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.79e-3)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (4.48e-3)" "unprognostic (6.51e-2)" "unprognostic (1.44e-1)" "unprognostic (4.38e-4)" "unprognostic (1.62e-1)" 2.0 3.0 14.9 3.3 14.8 0.0 4.9 4.6 39.1 4.7 0.3 36.0 17.9 5.8 4.2 5.7 15.4 1.3 83.1 18.3 7.7 0.8 1.3 0.9 0.5 13.8 6.0 1.1 42.8 2.3 29.6 3.0 8.8 16.7 11.9 28.8 47.3 12.3 62.3 15.8 21.5 4.5 1.9 2.7 14.7 6.6 14.2 7.1 1.8 31.0 1.0 5.5 3.4 10.5 7.4 6.6 4.6 13.2 0.0 0.0 8.8 0.0 0.0 0.1 0.0 2.7 0.2 18.8 2.4 0.0 1.3 0.3 10.4 0.0 0.0 0.0 12.1 0.0 5.8 31.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 12.2 0.0 0.0 9.8 0.2 0.2 11.5 7.2 0.4 0.0 0.0 15.3 0.0 1.1 37.6 14.8 2.4 10.2 0.9 1.3 1.3 2.2 0.1 0.0 4.8 0.2 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 14.9 14.8 4.6 39.1 18.3 7.7 13.8 6.0 8.8 1.9 14.2 10.5 0.3 0.0 0.0 76.4 0.3 1.3 8.5 3.1 0.0 62.0 19.4 18.7 58.1 31.5 14.1 0.0 160.6 15.5 0.2 34.3 0.0 17.1 1.2 7.7 9.2 1.3 32.4 0.0 128.5 9.1 6.7 2.7 3.6 15.8 0.0 8.6 0.4 0.2 3.4 1.7 98.8 77.3 6.1 1.3 2.2 2.6 0.9 0.1 1.8 29.0 0.6 60.3 0.0 9.0 3.2 3.2 57.0 6.0 0.2 11.1 47.7 1.1 6.6 106.8 13.1 3.5 5.0 0.7 7.7 1.1 5.5 15.6 0.4 0.1 59.0 8.9 WSB2 "MGC10210, SBA2" ENSG00000176871 "WD repeat and SOCS box containing 2" Q9NYS7 12 118032687-118062430 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052606 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052606: AB_2681882" "unprognostic (5.02e-3)" "unprognostic (4.57e-2)" "unprognostic (4.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.42e-3)" "unprognostic (4.66e-3)" "unprognostic (7.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.93e-1)" "unprognostic (4.05e-1)" "unprognostic (2.92e-1)" "unprognostic (2.66e-1)" "unprognostic (2.79e-1)" "unprognostic (2.42e-2)" 33.8 46.8 94.4 29.8 102.1 17.6 20.2 85.2 117.5 19.6 53.2 44.7 35.3 18.7 23.8 53.0 17.9 25.3 55.8 103.0 83.8 35.5 36.6 31.5 24.1 100.3 106.3 13.8 36.7 43.0 36.1 19.2 96.4 26.6 45.3 38.9 20.9 26.4 102.7 23.0 39.0 35.7 95.2 17.7 33.0 18.6 99.4 20.8 46.5 163.3 28.3 45.6 21.1 95.4 49.3 78.2 55.2 93.5 81.1 46.7 39.1 129.3 95.9 138.6 82.8 41.5 66.4 7.1 42.6 168.7 77.4 25.8 46.6 78.6 98.7 90.7 29.6 27.5 36.7 39.0 85.7 16.2 71.5 62.7 77.7 75.0 51.6 148.7 72.3 48.5 83.2 12.5 143.8 73.2 10.3 9.9 32.2 110.7 48.2 29.3 57.5 2.2 81.9 211.5 58.5 87.3 100.1 21.8 69.9 54.7 75.0 37.3 113.7 164.6 68.7 53.1 158.8 21.6 14.6 13.4 148.8 20.3 266.9 9.7 5.0 11.5 4.5 7.5 4.0 0.7 4.4 4.7 3.5 1.8 1.9 3.4 5.4 3.4 5.2 4.1 5.1 1.8 94.4 102.1 85.2 117.5 103.0 83.8 100.3 106.3 96.4 95.2 99.4 95.4 17.1 25.6 15.7 14.7 5.9 16.6 39.4 16.4 5.2 21.0 20.2 10.3 33.7 24.3 14.1 20.2 4.2 10.0 11.8 75.1 21.5 37.4 2.0 19.5 23.6 16.7 72.7 7.4 45.9 85.1 24.3 19.6 23.0 31.5 7.0 13.1 17.2 36.4 34.7 57.2 31.9 40.7 22.4 51.8 18.4 4.7 7.5 23.5 28.4 18.7 34.8 34.1 11.3 18.1 30.7 89.6 44.5 17.3 6.2 53.4 47.7 35.6 7.2 14.1 13.1 21.8 26.0 3.2 5.1 17.8 18.6 17.2 13.1 44.8 25.8 86.9 XIAP "API3, BIRC4, hILP, ILP-1" ENSG00000101966 "X-linked inhibitor of apoptosis" P98170 X 123859724-123913976 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway, Wnt signaling pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009203, HPA042428" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009203: AB_2257167, HPA042428: AB_2677993" "prognostic unfavorable (9.21e-4)" "unprognostic (8.43e-2)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (9.41e-2)" "unprognostic (1.95e-2)" "unprognostic (8.51e-2)" "unprognostic (9.17e-2)" "unprognostic (3.90e-2)" "unprognostic (7.50e-2)" "unprognostic (4.41e-2)" "unprognostic (3.15e-3)" "unprognostic (8.21e-3)" "unprognostic (2.26e-1)" "unprognostic (4.99e-2)" "unprognostic (4.65e-2)" 9.2 7.7 6.5 9.2 7.5 8.3 9.7 6.8 7.0 9.6 12.9 12.4 10.1 8.4 10.0 11.5 7.4 8.6 7.8 5.8 8.2 11.8 12.1 8.5 10.4 7.6 8.1 7.5 8.3 18.4 6.3 8.6 7.3 8.5 10.1 21.4 8.6 7.4 10.3 8.8 10.1 7.4 8.5 10.4 10.2 4.2 8.1 8.9 14.9 11.9 8.6 9.6 6.1 10.3 15.8 13.2 10.2 8.8 11.8 15.0 13.3 16.9 12.4 8.9 7.7 5.9 17.9 14.7 24.3 14.4 17.1 5.6 15.3 10.5 16.3 15.5 8.3 9.9 11.1 9.2 14.9 18.1 19.7 10.4 16.0 14.9 19.0 10.2 12.7 10.8 15.9 16.4 17.6 16.5 10.2 8.8 8.4 15.6 10.3 10.8 11.9 15.6 13.4 22.6 6.8 10.0 22.9 13.0 13.5 9.0 8.0 8.7 15.7 0.5 6.0 27.0 18.9 13.8 14.9 15.8 18.3 12.7 11.5 9.3 1.8 2.6 3.3 1.5 3.0 3.1 2.4 3.6 1.0 4.0 2.7 1.9 5.6 2.4 2.9 2.9 1.8 1.5 6.5 7.5 6.8 7.0 5.8 8.2 7.6 8.1 7.3 8.5 8.1 10.3 50.0 80.1 91.6 26.4 42.1 26.6 36.3 35.0 28.5 72.1 29.7 19.9 44.5 44.3 55.2 53.3 95.9 17.9 41.7 122.9 27.4 36.0 2.7 38.4 44.9 55.0 47.4 23.5 30.0 54.0 30.0 38.4 39.8 50.4 60.7 30.9 64.2 85.8 29.0 75.7 34.9 62.2 26.4 43.6 33.0 4.1 42.6 44.2 8.8 29.0 45.8 45.8 55.6 32.6 41.9 65.4 53.5 51.6 39.5 53.0 59.2 59.8 50.6 133.7 65.7 43.6 34.9 15.2 21.0 30.8 35.5 38.0 40.8 30.0 48.0 68.1 ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments" "HPA059339: AB_2683985" "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" 18.8 23.9 7.8 15.5 7.7 41.3 19.3 7.5 9.9 16.8 8.4 40.5 26.3 12.9 7.1 67.8 12.0 14.1 13.7 7.4 8.8 30.6 52.3 23.3 20.0 9.6 7.8 7.4 67.1 9.8 11.3 16.3 8.4 26.6 13.7 0.5 43.2 12.5 15.6 42.4 36.8 6.3 8.4 31.7 49.2 24.7 10.5 12.4 16.2 4.1 13.7 18.7 30.5 9.7 53.5 127.6 6.0 31.3 17.6 12.1 59.4 32.8 28.8 34.5 22.9 109.6 61.5 37.3 29.6 25.5 62.9 139.8 13.0 65.0 3.8 65.0 31.7 20.1 92.7 49.1 34.7 33.1 87.1 19.9 44.7 29.6 11.0 17.7 25.6 65.6 18.8 93.6 7.1 187.3 45.9 66.2 26.8 118.8 107.6 21.0 21.0 108.4 28.7 43.4 42.1 30.4 46.2 64.1 18.3 9.6 98.9 35.6 27.5 0.1 36.9 25.9 45.8 58.1 106.8 17.3 61.3 38.4 41.4 231.1 122.3 385.6 105.1 123.9 91.2 94.6 95.9 101.5 100.1 111.0 99.2 91.4 269.5 90.5 150.0 244.7 130.9 101.0 7.8 7.7 7.5 9.9 7.4 8.8 9.6 7.8 8.4 8.4 10.5 9.7 10.0 16.0 12.0 1.3 31.8 16.2 43.3 94.0 10.8 1.2 55.5 30.4 14.8 77.2 59.0 46.0 0.0 183.9 39.1 171.0 13.7 106.8 73.2 20.7 11.5 21.1 51.2 51.1 0.6 200.0 224.0 14.2 38.7 52.5 18.4 13.7 35.7 55.3 137.0 0.0 0.5 108.5 67.1 62.2 20.9 30.0 9.6 46.5 42.7 6.5 115.3 18.4 81.4 0.5 2.0 133.8 167.7 7.2 43.3 56.5 186.0 48.5 20.1 2.0 6.6 5.4 16.3 36.0 18.6 55.2 28.1 134.1 34.1 22.0 110.0 77.5 ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type palmitoyltransferase 18" Q9NUE0 1 26826688-26857604 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 48.8" "Cell line enhanced" "Detected in all" "HDLM-2: 132.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040234 Approved Approved Microtubules NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 23.4 8.1 26.0 27.4 24.6 113.9 17.0 25.7 29.0 12.9 16.9 14.6 12.9 13.6 4.6 24.3 11.3 14.8 15.0 25.4 30.0 8.8 18.6 16.2 22.1 29.1 28.7 9.6 10.5 8.6 11.7 23.3 33.5 11.4 15.0 19.3 16.9 9.1 10.8 18.5 13.9 18.4 22.2 31.3 12.4 7.4 28.5 14.7 15.3 16.1 20.9 22.7 14.4 25.1 45.3 19.8 31.5 21.8 25.6 17.8 30.9 26.7 31.5 45.9 33.9 18.3 28.4 20.9 16.7 35.5 24.0 31.3 33.8 15.9 39.2 132.6 28.7 20.3 15.3 25.7 22.0 18.1 16.9 15.5 21.3 42.3 27.9 16.5 25.9 31.6 21.4 41.8 18.4 22.1 34.5 14.6 30.4 28.1 18.8 28.3 27.2 22.2 19.2 11.3 14.6 17.7 17.9 13.4 19.3 23.9 12.1 17.6 22.2 31.5 24.2 52.3 31.0 49.7 38.8 18.1 17.9 32.5 21.9 0.0 0.5 10.0 1.6 1.1 1.1 0.4 1.2 1.2 0.8 0.3 0.7 0.8 48.8 1.0 0.8 0.4 2.7 0.5 26.0 24.6 25.7 29.0 25.4 30.0 29.1 28.7 33.5 22.2 28.5 25.1 12.9 9.6 7.9 6.5 7.5 25.6 8.6 4.4 6.8 39.8 8.4 6.6 6.0 10.0 6.8 1.8 27.1 10.6 21.2 27.0 0.0 4.1 3.8 6.1 7.0 9.1 3.0 9.3 10.2 2.8 7.1 7.1 4.6 12.7 1.3 5.9 7.9 12.0 7.3 18.5 10.2 3.9 2.0 8.5 17.0 2.1 6.2 11.0 10.6 5.6 26.6 5.7 12.3 4.0 6.3 8.0 25.6 3.8 8.3 19.3 10.4 2.2 4.6 35.3 0.0 7.1 6.2 3.5 11.4 14.6 36.2 6.2 17.4 8.0 7.0 34.7 ZER1 "C9orf60, Hzyg, ZYG, ZYG11BL" ENSG00000160445 "Zyg-11 related cell cycle regulator" Q7Z7L7 9 128729786-128772414 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 67.7;Inhibitory neurons: 61.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048464 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA048464: AB_2756306" "unprognostic (1.37e-1)" "prognostic favorable (1.18e-6)" "unprognostic (9.11e-3)" "unprognostic (2.36e-2)" "unprognostic (7.46e-2)" "unprognostic (9.35e-2)" "unprognostic (2.18e-1)" "unprognostic (4.81e-3)" "unprognostic (3.65e-1)" "unprognostic (4.90e-3)" "unprognostic (6.65e-3)" "unprognostic (1.69e-1)" "prognostic favorable (5.15e-11)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.14e-1)" 24.3 31.0 57.4 12.4 56.4 17.1 23.8 28.3 72.8 26.7 23.2 38.9 33.3 29.8 13.1 28.6 25.9 17.4 44.1 59.7 48.2 26.5 22.9 19.9 13.9 44.6 40.1 28.1 26.6 31.9 33.5 15.9 44.8 31.7 13.0 17.3 27.4 24.7 72.0 33.8 31.5 16.4 28.5 19.6 26.9 36.6 43.8 19.2 26.5 43.6 11.3 31.0 24.7 46.1 17.3 19.1 12.4 17.0 36.4 24.9 34.3 16.7 28.4 22.6 18.1 17.3 19.6 10.6 18.1 29.3 16.9 37.1 13.8 24.8 9.5 21.2 17.7 7.0 34.2 12.4 28.3 11.1 20.1 31.1 36.6 22.9 16.1 30.6 19.5 21.2 13.7 22.9 15.5 65.9 20.9 12.5 12.3 24.6 24.4 18.6 15.6 41.4 16.8 23.4 23.7 17.9 26.7 35.4 18.9 14.4 52.0 12.7 22.2 18.4 7.8 23.5 10.2 28.7 29.3 8.6 27.2 6.6 13.5 11.5 3.2 8.8 4.4 4.7 6.0 3.0 4.7 5.7 3.3 3.8 4.9 4.7 13.6 5.1 5.2 4.9 4.7 5.0 57.4 56.4 28.3 72.8 59.7 48.2 44.6 40.1 44.8 28.5 43.8 46.1 10.7 12.8 16.8 33.0 8.0 2.8 2.9 5.2 6.2 20.2 13.0 12.6 22.6 4.3 4.7 5.5 14.6 4.8 4.8 41.7 1.9 5.8 7.1 15.2 8.6 9.0 7.2 17.9 67.7 9.6 2.5 8.6 13.7 11.8 10.2 12.0 7.1 13.0 6.2 21.9 61.2 15.0 2.0 4.4 1.0 2.4 11.1 5.7 8.8 16.9 9.5 9.8 6.2 23.1 48.9 7.1 23.2 10.5 8.7 6.4 25.4 13.8 13.5 13.4 13.1 9.2 9.1 10.6 3.5 8.0 5.8 8.5 7.1 16.0 9.6 3.4 ZFAND2B AIRAPL ENSG00000158552 "Zinc finger AN1-type containing 2B" Q8WV99 2 219195237-219209651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 144.0;Proximal enterocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035159, HPA035160" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA035159: AB_2674499, HPA035160: AB_10670697" "unprognostic (3.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.77e-3)" "unprognostic (2.59e-1)" "unprognostic (2.97e-1)" "unprognostic (6.85e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (7.36e-2)" "unprognostic (1.20e-1)" "prognostic favorable (9.38e-4)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-3)" "unprognostic (1.32e-1)" "unprognostic (6.21e-2)" "unprognostic (7.02e-2)" 28.5 26.6 33.2 20.7 34.3 38.2 28.3 34.4 43.7 38.2 27.4 41.6 41.5 29.7 18.1 48.8 28.5 20.0 28.1 33.3 34.0 44.1 64.5 32.3 28.4 37.2 33.3 29.0 40.7 26.8 36.2 17.4 34.3 31.3 25.0 10.8 27.7 17.6 34.3 42.5 45.4 15.9 33.1 45.9 37.4 15.6 34.3 37.9 49.8 15.5 23.3 33.0 35.5 37.5 23.0 14.4 17.2 23.7 17.6 18.5 23.5 22.8 26.3 32.1 31.7 34.8 18.9 16.5 23.0 39.2 26.0 15.5 15.4 28.9 25.5 27.8 25.2 41.8 25.6 30.3 36.3 22.9 45.3 15.3 62.2 31.9 75.0 17.7 21.2 40.0 25.0 38.9 31.9 40.0 37.9 47.9 8.9 31.7 17.5 22.4 8.3 31.6 29.6 17.7 33.7 16.3 10.9 17.3 24.8 19.3 15.4 47.3 22.5 32.2 29.5 37.2 33.3 20.2 6.6 34.1 31.5 44.2 25.6 30.8 34.8 48.6 49.1 46.0 42.5 43.6 44.2 48.0 26.7 53.0 39.9 48.9 58.3 53.5 38.3 33.5 51.6 44.3 33.2 34.3 34.4 43.7 33.3 34.0 37.2 33.3 34.3 33.1 34.3 37.5 30.4 22.4 21.2 17.6 43.5 27.1 26.3 34.0 19.9 14.9 37.1 33.7 12.7 44.3 24.5 20.2 14.6 26.9 52.4 144.0 56.7 44.1 4.9 14.6 17.7 26.4 40.2 15.2 17.8 66.0 24.3 19.6 42.3 20.7 32.4 11.6 23.6 39.4 34.9 8.4 16.1 67.5 36.7 32.4 31.3 7.8 32.0 35.6 35.6 5.6 24.4 21.5 44.3 6.0 15.3 60.3 101.1 29.7 39.5 25.1 170.6 79.5 13.8 17.2 26.3 15.9 28.7 6.2 22.9 27.6 36.1 51.3 46.7 27.8 54.4 28.8 ZNF165 "CT53, ZSCAN7" ENSG00000197279 "Zinc finger protein 165" P49910 6 28080568-28089563 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 94.6;Early spermatids: 152.7;Glandular and luminal cells: 75.8;Paneth cells: 120.3;Syncytiotrophoblasts: 79.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 14.4;BEWO: 22.9;GAMG: 16.9" "Low region specificity" "Detected in all" HPA007247 Approved "Nuclear speckles,Microtubules" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Microtubules" "HPA007247: AB_2797217" "unprognostic (1.85e-1)" "unprognostic (2.01e-3)" "unprognostic (1.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.45e-1)" "unprognostic (4.32e-3)" "unprognostic (3.42e-1)" "unprognostic (2.09e-1)" "unprognostic (1.93e-2)" "prognostic favorable (2.10e-4)" "unprognostic (1.18e-3)" "unprognostic (1.29e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.10e-1)" "unprognostic (2.40e-1)" "unprognostic (2.18e-1)" "prognostic favorable (9.82e-5)" 0.4 0.8 0.4 1.0 0.5 1.4 2.1 0.6 0.8 1.4 2.1 2.4 2.2 1.1 5.1 2.2 1.8 0.9 0.5 0.5 0.5 4.5 2.4 1.9 1.3 0.9 0.7 0.7 4.6 4.8 3.8 3.1 1.0 1.0 3.3 1.7 2.0 1.2 0.7 1.0 1.8 0.5 0.4 0.9 2.5 17.2 0.4 0.5 2.9 0.1 1.7 2.5 1.1 0.7 14.4 0.9 0.8 1.1 0.3 0.5 22.9 0.5 0.5 0.9 0.8 9.0 10.3 1.2 3.9 0.2 16.9 5.4 2.0 6.2 0.6 0.4 3.6 0.7 1.5 9.7 0.3 2.3 2.0 0.3 3.2 0.7 8.8 0.6 0.3 0.8 2.3 1.1 0.5 3.9 0.6 2.7 1.9 12.2 1.4 1.9 0.8 7.7 4.7 6.5 9.6 0.7 1.2 11.1 1.3 2.5 5.5 0.5 0.4 0.8 1.1 0.4 1.0 3.4 9.6 3.6 0.5 2.6 0.4 5.8 1.7 3.4 1.3 1.4 1.6 7.0 1.5 1.0 1.8 8.6 2.5 2.0 2.5 1.4 1.7 5.5 0.7 0.9 0.4 0.5 0.6 0.8 0.5 0.5 0.9 0.7 1.0 0.4 0.4 0.7 0.8 6.4 7.0 0.0 23.2 8.5 16.5 2.3 2.8 0.8 24.5 9.4 0.4 4.3 5.0 3.7 0.0 9.4 4.2 94.6 3.9 18.2 152.7 55.4 5.9 1.3 53.9 0.0 1.2 12.3 9.0 0.6 13.7 75.8 0.0 0.6 0.0 0.4 1.5 0.0 0.9 53.7 6.1 0.6 3.2 19.5 0.9 2.8 5.4 0.0 1.6 1.5 0.0 0.0 0.1 17.5 120.3 2.2 12.4 6.5 9.0 2.0 12.0 2.6 0.0 0.6 1.5 33.6 4.4 8.5 11.8 79.6 8.5 0.3 34.9 40.8 ZNF341 dJ553F4.3 ENSG00000131061 "Zinc finger protein 341" Q9BYN7 20 33731657-33792269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023240, HPA024607, HPA067108" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA023240: AB_1859207, HPA024607: AB_1859208, HPA067108: AB_2685780" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (3.73e-1)" "unprognostic (2.10e-1)" "unprognostic (9.31e-2)" "prognostic favorable (3.93e-4)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.44e-1)" "unprognostic (1.70e-1)" "unprognostic (1.80e-1)" "unprognostic (7.38e-2)" "unprognostic (9.31e-2)" "unprognostic (8.17e-5)" "unprognostic (4.84e-2)" "unprognostic (2.90e-1)" "unprognostic (8.67e-3)" "unprognostic (3.68e-2)" 1.2 0.9 1.0 1.9 1.1 2.4 0.9 0.8 2.2 1.1 0.0 1.5 1.4 1.3 1.0 1.3 1.3 0.9 1.0 1.6 0.2 0.6 0.6 1.1 1.9 0.3 0.1 1.3 1.6 0.9 0.6 1.4 0.4 1.3 1.1 0.7 1.5 1.0 3.3 2.1 1.0 1.2 0.2 1.9 1.4 1.5 0.5 1.8 0.9 3.3 1.2 1.2 1.1 1.3 2.4 6.4 2.2 4.7 2.1 1.7 9.5 2.3 1.2 1.9 1.2 4.6 5.4 3.7 3.8 1.7 2.2 3.7 2.4 4.1 0.8 3.3 2.2 3.6 3.6 3.7 1.2 2.1 4.3 1.4 3.0 1.6 1.0 1.7 2.3 3.4 1.9 1.7 2.0 2.9 1.9 1.6 3.0 3.5 3.1 2.4 1.4 2.1 1.3 5.2 1.9 2.1 6.1 5.6 1.4 1.7 5.0 1.7 2.9 3.4 1.4 2.5 2.2 1.3 1.9 3.4 3.3 1.7 2.4 2.6 1.3 2.9 1.1 1.8 1.0 2.2 0.8 0.7 1.0 1.2 0.5 1.5 2.5 1.3 1.2 0.7 0.6 0.9 1.0 1.1 0.8 2.2 1.6 0.2 0.3 0.1 0.4 0.2 0.5 1.3 1.8 3.2 5.1 5.5 2.9 0.4 1.0 1.5 0.6 2.2 1.9 1.4 2.7 2.8 4.7 1.8 2.1 2.6 0.9 7.0 0.0 1.5 0.6 1.6 1.4 1.4 1.2 0.8 11.3 1.4 3.3 1.6 6.6 2.1 2.5 1.8 1.4 1.0 1.4 1.7 8.0 2.0 2.0 1.6 2.0 0.1 0.6 2.4 0.0 3.7 1.2 0.6 2.1 6.0 7.7 1.7 2.5 0.4 2.6 2.5 4.2 0.4 4.6 2.3 0.0 1.9 1.1 1.6 2.4 1.6 1.0 2.1 1.9 1.5 2.4 2.5 ZNF524 MGC23143 ENSG00000171443 "Zinc finger protein 524" Q96C55 19 55600022-55603138 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 96.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050981 Uncertain Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA050981: AB_2681298" "unprognostic (6.69e-2)" "unprognostic (1.23e-2)" "unprognostic (5.70e-2)" "unprognostic (4.27e-3)" "unprognostic (2.88e-2)" "unprognostic (3.63e-2)" "unprognostic (1.30e-2)" "unprognostic (5.13e-2)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (2.13e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (3.84e-1)" "unprognostic (1.59e-2)" "prognostic favorable (4.98e-8)" 22.5 19.4 14.0 7.7 14.4 9.9 22.2 14.0 18.9 18.8 13.1 22.5 14.9 18.2 3.4 26.7 17.6 6.1 23.5 12.2 12.2 20.9 28.6 18.0 9.6 15.9 14.4 16.4 67.9 7.2 18.5 4.4 14.7 21.8 3.8 1.7 24.6 5.4 45.5 37.2 19.4 2.7 14.0 27.7 34.5 6.9 13.9 6.1 20.4 10.9 3.7 19.9 19.6 16.2 12.1 11.3 1.7 7.5 5.3 10.6 12.4 7.4 4.3 4.6 4.7 3.4 13.1 6.1 4.4 4.0 2.6 9.2 1.1 5.6 0.6 18.9 29.2 7.5 6.7 5.9 12.3 4.7 9.2 8.7 13.4 3.8 3.9 4.7 8.8 7.3 7.4 11.4 2.6 6.7 4.7 10.1 2.0 11.1 13.3 6.2 3.9 18.5 5.9 6.4 8.0 5.4 7.6 10.1 8.6 1.2 4.8 15.3 7.9 4.0 6.9 7.6 9.5 5.2 6.9 2.8 10.3 12.0 5.3 15.0 23.9 20.1 13.4 21.2 12.4 11.9 13.7 12.9 18.6 14.4 16.0 8.9 14.6 12.4 14.1 5.6 22.1 15.2 14.0 14.4 14.0 18.9 12.2 12.2 15.9 14.4 14.7 14.0 13.9 16.2 38.5 6.4 14.1 1.6 19.4 25.2 17.2 25.5 23.9 8.5 36.3 42.4 10.1 20.0 16.1 7.3 6.2 22.0 17.8 73.0 17.6 25.0 2.4 16.9 13.4 27.1 23.4 9.4 1.8 53.6 19.5 14.8 34.7 14.5 10.2 12.0 40.4 22.9 38.1 6.7 1.7 62.9 6.1 75.8 27.8 7.5 18.0 37.7 30.2 4.7 46.6 10.1 34.0 1.5 5.8 33.4 56.9 21.8 14.5 18.2 96.1 38.1 8.8 8.4 19.7 14.4 17.6 1.1 6.1 30.9 35.7 25.6 23.4 18.5 46.1 20.5 ZNF575 FLJ32567 ENSG00000176472 "Zinc finger protein 575" Q86XF7 19 43525497-43536130 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 18.9;Paneth cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MOLT-4: 7.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051865 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA051865: AB_2681643" "unprognostic (1.77e-3)" "unprognostic (2.73e-2)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "unprognostic (8.56e-2)" "unprognostic (6.53e-4)" "unprognostic (1.23e-1)" "unprognostic (2.37e-1)" "unprognostic (2.36e-2)" "unprognostic (2.21e-1)" "unprognostic (3.87e-5)" "unprognostic (1.10e-1)" "unprognostic (4.64e-2)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (7.83e-2)" "unprognostic (2.75e-1)" 2.8 1.6 1.5 1.1 2.2 0.6 2.1 2.5 4.4 3.0 0.0 4.5 1.6 2.9 1.0 1.6 2.3 0.7 2.3 2.1 0.0 2.1 2.1 1.6 1.1 0.9 0.2 3.1 1.5 0.5 3.2 0.4 0.9 2.1 2.0 0.6 1.7 1.0 4.6 2.0 2.2 0.8 0.0 2.1 1.5 0.8 1.1 1.1 2.1 0.5 0.6 2.2 2.3 1.5 1.9 1.7 0.4 0.5 2.4 2.0 0.1 1.2 0.8 0.4 0.6 0.4 0.7 0.4 0.8 0.9 0.2 1.0 0.0 0.2 0.2 2.7 0.3 1.4 0.7 0.3 0.5 0.6 1.7 1.2 0.7 0.6 0.1 1.3 0.3 2.6 0.5 2.6 0.7 1.3 7.7 0.2 0.1 1.3 0.8 4.1 0.0 1.0 0.4 1.1 0.3 0.6 0.9 1.2 1.3 0.3 0.3 0.7 1.3 2.3 1.5 0.5 0.9 1.3 2.2 1.2 1.4 1.7 2.4 0.0 0.4 0.3 1.4 0.2 0.5 0.7 1.3 1.4 0.6 1.8 2.1 1.5 0.4 3.3 0.2 0.9 1.4 0.7 1.5 2.2 2.5 4.4 2.1 0.0 0.9 0.2 0.9 0.0 1.1 1.5 1.5 6.4 1.1 1.6 1.3 0.1 0.6 1.2 1.8 1.2 1.1 1.9 2.0 0.0 0.9 0.0 4.2 1.3 1.9 18.9 3.9 0.4 0.1 0.5 1.6 1.8 1.2 1.3 0.9 0.6 0.9 3.5 1.1 1.1 0.0 1.5 2.5 2.3 1.6 0.0 1.1 2.3 0.0 2.7 1.0 0.4 2.5 1.8 1.8 0.0 0.8 0.8 4.1 0.0 1.3 0.2 8.7 3.4 2.6 0.3 2.0 2.5 0.2 0.1 0.0 2.0 2.6 0.1 1.1 2.6 1.7 0.3 3.1 0.7 2.7 0.5 ZNF622 "MGC17552, MGC2485, ZPR9" ENSG00000173545 "Zinc finger protein 622" Q969S3 5 16451519-16465800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036514, HPA036515" Uncertain Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA036514: AB_2675167, HPA036515: AB_10672224" "unprognostic (6.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.00e-2)" "unprognostic (6.53e-2)" "unprognostic (8.24e-3)" "unprognostic (4.71e-3)" "unprognostic (1.06e-1)" "unprognostic (1.71e-1)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" "unprognostic (8.69e-2)" "unprognostic (5.93e-2)" "unprognostic (2.19e-1)" "unprognostic (7.42e-2)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" 19.5 13.5 20.3 13.8 21.4 36.0 18.4 17.2 21.8 16.7 14.4 21.5 16.9 17.8 17.2 17.9 15.3 12.1 56.9 18.1 19.6 14.6 22.0 16.6 17.8 18.7 20.7 15.6 54.3 15.6 15.1 16.9 20.3 15.5 20.7 10.8 18.3 12.7 41.7 25.6 20.3 12.5 19.1 15.5 22.4 20.5 19.4 16.0 15.5 25.2 15.7 17.5 17.0 22.1 25.7 55.2 16.9 35.2 40.4 34.3 61.4 45.2 33.9 36.0 45.6 66.0 23.2 30.0 59.6 36.0 48.4 33.3 27.5 35.3 28.9 40.6 37.3 27.4 92.8 47.7 58.1 53.8 31.5 53.3 43.7 33.6 31.5 28.0 25.6 17.6 37.6 28.9 40.1 43.2 28.4 52.3 30.0 24.2 53.8 22.1 20.6 25.8 33.6 38.0 23.4 26.2 63.1 46.8 78.2 29.4 26.0 41.1 35.3 40.0 30.5 39.3 29.1 41.3 39.7 41.9 34.9 45.8 28.5 89.3 65.6 88.6 73.8 71.3 77.8 85.4 73.7 82.0 73.3 81.9 84.2 70.3 87.9 67.9 79.6 59.2 85.0 82.6 20.3 21.4 17.2 21.8 18.1 19.6 18.7 20.7 20.3 19.1 19.4 22.1 14.8 22.4 24.2 2.9 33.2 60.7 43.1 48.6 34.1 22.8 19.8 16.4 73.8 24.3 34.4 14.7 10.4 64.0 39.5 77.5 27.4 55.2 111.5 35.0 36.8 22.3 98.7 20.0 7.6 66.7 57.2 34.1 31.1 71.3 52.0 13.3 15.0 25.1 50.0 16.8 7.9 60.6 48.8 19.3 35.1 62.8 18.0 29.7 33.8 4.7 43.3 22.6 37.0 6.6 9.0 51.2 127.1 19.9 26.6 28.3 84.5 39.2 29.7 19.3 19.7 31.7 46.9 63.2 37.8 21.8 43.2 40.6 41.6 20.5 55.5 33.5 ZNF768 FLJ23436 ENSG00000169957 "Zinc finger protein 768" Q9H5H4 16 30524004-30526821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024630, HPA066512" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA024630: AB_1859446, HPA066512: AB_2685683" "unprognostic (2.33e-1)" "unprognostic (6.16e-2)" "unprognostic (2.28e-2)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" "unprognostic (1.73e-1)" "unprognostic (7.94e-3)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (3.26e-2)" "unprognostic (2.74e-1)" "prognostic favorable (9.30e-6)" "unprognostic (4.49e-2)" "unprognostic (1.94e-1)" "unprognostic (3.13e-1)" "prognostic favorable (6.46e-4)" 22.3 23.2 31.4 9.9 32.9 13.3 22.6 30.6 35.0 28.7 28.3 42.6 29.8 30.8 9.9 22.8 27.5 10.1 49.3 27.8 27.7 34.8 38.5 19.0 7.3 32.3 31.9 28.9 25.7 30.2 27.2 11.3 30.3 30.3 17.0 13.7 25.6 21.1 93.8 28.2 31.1 13.4 28.5 22.1 30.9 39.3 33.0 6.0 23.7 53.1 7.4 34.9 23.0 29.9 27.1 33.3 37.0 36.1 17.6 20.3 29.1 20.2 22.5 32.7 28.4 21.3 36.8 17.1 30.1 14.2 26.3 35.4 24.8 24.1 19.4 38.5 52.6 40.0 24.0 30.0 44.1 26.8 121.3 17.9 52.5 25.1 32.4 30.2 21.9 6.7 47.4 28.0 17.1 74.9 10.0 64.7 34.8 22.0 27.1 50.7 24.7 42.5 23.9 14.0 43.6 48.4 11.5 59.9 77.3 15.9 59.3 66.5 14.9 34.2 25.9 19.4 22.8 41.3 32.4 21.1 28.5 41.4 35.2 0.0 0.4 1.0 0.0 0.6 0.1 1.1 0.1 0.0 0.6 0.4 0.1 0.0 0.5 0.6 0.1 0.5 0.0 0.2 31.4 32.9 30.6 35.0 27.8 27.7 32.3 31.9 30.3 28.5 33.0 29.9 9.7 9.6 1.9 8.8 4.1 5.5 6.7 9.5 6.8 13.3 15.4 12.6 7.6 14.3 5.5 16.5 2.1 7.2 2.0 50.4 11.7 12.2 18.4 10.9 9.9 9.2 18.0 3.8 2.6 16.2 8.0 6.5 10.7 13.3 3.8 15.5 14.6 17.9 12.7 21.9 3.4 29.1 8.2 8.1 7.7 7.4 10.8 6.1 5.4 4.7 6.8 16.5 0.0 4.0 4.5 11.6 38.2 13.2 2.2 7.9 38.9 17.0 7.4 12.7 6.6 11.8 10.5 15.2 5.1 10.0 5.7 3.6 2.1 14.1 31.3 5.3 ZNF784 MGC75238 ENSG00000179922 "Zinc finger protein 784" Q8NCA9 19 55620741-55624566 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059676 Uncertain Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA059676: AB_2684102" "unprognostic (4.67e-2)" "unprognostic (8.13e-2)" "unprognostic (4.03e-1)" "unprognostic (6.46e-3)" "unprognostic (1.17e-1)" "unprognostic (2.63e-2)" "unprognostic (2.28e-1)" "unprognostic (9.44e-2)" "unprognostic (4.74e-1)" "unprognostic (1.26e-1)" "unprognostic (9.11e-3)" "unprognostic (4.86e-2)" "unprognostic (3.48e-3)" "unprognostic (3.87e-1)" "unprognostic (7.93e-2)" "unprognostic (5.10e-2)" "prognostic favorable (1.02e-4)" 4.5 8.5 3.0 3.0 2.9 6.2 5.3 4.3 3.9 8.6 2.2 12.8 8.3 10.7 3.8 7.2 9.2 2.7 13.9 2.8 2.2 7.8 11.5 4.8 3.5 3.6 2.7 11.8 11.3 4.2 7.7 2.6 2.5 11.2 3.3 4.4 6.7 3.7 42.8 6.7 10.2 3.6 2.3 9.1 8.9 5.4 2.9 2.0 7.4 16.0 2.8 10.6 6.6 3.6 4.6 6.4 5.8 3.1 2.2 2.9 5.5 4.7 2.9 2.6 3.5 3.2 5.0 5.5 4.0 3.3 2.0 2.5 1.7 4.1 1.8 3.0 16.7 5.1 5.1 4.1 4.4 4.2 5.3 4.0 4.4 2.2 2.8 4.2 1.7 7.7 6.1 5.5 4.0 4.4 3.3 4.8 5.7 3.5 13.7 6.2 3.9 6.2 4.8 11.5 6.5 8.7 7.7 3.6 2.2 3.8 3.9 7.4 5.4 3.0 2.9 1.9 3.9 6.3 2.8 3.2 4.6 3.1 2.6 0.0 0.4 0.6 0.1 0.4 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.2 0.2 0.3 0.3 0.2 0.0 0.1 3.0 2.9 4.3 3.9 2.8 2.2 3.6 2.7 2.5 2.3 2.9 3.6 1.9 0.0 7.4 1.6 3.4 0.9 4.7 1.5 2.8 4.7 2.2 3.2 12.3 8.6 1.9 0.0 2.1 5.5 1.3 10.9 3.9 4.0 2.1 2.7 2.5 2.3 5.4 4.4 0.5 4.1 2.4 3.2 1.5 3.2 2.5 5.5 3.9 6.8 3.5 8.4 0.6 6.2 6.1 3.5 1.0 0.1 4.1 2.4 0.0 1.0 4.5 4.2 0.0 1.5 1.1 4.5 7.4 2.6 2.3 2.1 11.2 5.2 2.2 11.0 13.1 2.9 2.7 0.6 2.3 1.8 1.3 10.1 2.0 7.7 5.5 3.7