Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACAP2 "CENTB2, CNT-B2, KIAA0041" ENSG00000114331 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 2" Q15057 3 195274745-195443044 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 215.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034807, HPA034808" Supported Approved Endosomes NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Endosomes "HPA034807: AB_10669896, HPA034808: AB_10673103" "unprognostic (9.13e-2)" "unprognostic (1.75e-3)" "unprognostic (7.05e-2)" "unprognostic (2.16e-2)" "unprognostic (2.90e-2)" "unprognostic (5.64e-2)" "unprognostic (3.08e-3)" "unprognostic (7.17e-2)" "unprognostic (3.18e-2)" "unprognostic (1.57e-1)" "unprognostic (5.49e-2)" "unprognostic (2.36e-2)" "unprognostic (1.01e-2)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (3.77e-2)" "unprognostic (8.54e-2)" 15.9 10.2 10.7 22.2 10.3 39.6 13.5 21.4 14.5 14.3 1.8 17.0 14.0 14.4 10.9 21.7 12.2 14.2 8.3 14.1 6.4 10.3 11.8 15.7 26.9 2.5 4.2 19.0 9.0 13.2 8.5 15.5 6.1 10.7 17.3 29.4 9.5 10.4 5.3 15.5 15.3 14.5 3.3 23.6 14.0 15.1 5.0 21.0 21.7 9.7 27.9 13.5 11.5 7.7 34.6 13.5 21.5 21.1 34.3 41.9 31.6 28.0 37.2 20.5 21.4 18.5 19.8 38.7 65.7 25.8 20.0 21.6 16.5 14.0 29.4 43.4 9.7 38.5 14.2 7.6 33.5 52.5 26.7 32.3 24.0 20.4 46.1 17.6 22.7 21.4 19.1 37.0 30.3 20.3 33.7 19.1 13.0 19.8 18.1 39.7 24.8 27.8 14.1 32.2 23.8 11.5 30.7 27.4 32.9 18.2 51.7 30.6 40.3 25.9 14.7 34.6 32.7 21.8 50.2 84.0 19.1 56.2 27.5 62.8 55.2 55.3 27.5 49.0 21.2 39.3 26.1 21.3 32.9 45.6 22.0 22.4 215.8 17.6 59.0 34.4 26.2 25.4 10.7 10.3 21.4 14.5 14.1 6.4 2.5 4.2 6.1 3.3 5.0 7.7 110.7 44.8 40.9 103.8 103.1 44.5 28.8 45.1 88.2 58.7 43.1 50.3 17.9 22.8 43.4 31.3 77.2 20.2 101.9 75.8 19.6 24.1 11.1 49.7 60.4 74.1 51.6 50.1 141.2 24.3 22.2 62.2 44.4 49.7 39.9 33.5 57.5 32.5 65.4 121.1 143.1 44.4 22.4 115.7 67.5 9.7 46.6 110.8 35.6 143.4 122.3 29.1 68.0 132.7 130.1 31.7 70.7 37.6 67.6 41.5 39.3 28.6 45.1 92.6 59.2 43.8 61.4 39.6 26.7 143.7 51.7 29.0 85.1 43.0 37.6 38.6 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 AIM2 PYHIN4 ENSG00000163568 "Absent in melanoma 2" O14862 1 159062484-159147096 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" DNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.5;lymphoid tissue: 50.3" "Group enriched" "Detected in some" 4 "B-cells: 64.2;Early spermatids: 24.0;Late spermatids: 33.3;Plasma cells: 40.1" "Cancer enhanced" "Detected in many" "cervical cancer: 15.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "memory B-cell: 143.8;naive B-cell: 63.7" "Lineage enriched" "Detected in many" 7 "B-cells: 143.8" "Cell line enhanced" "Detected in some" "Daudi: 94.6;HDLM-2: 132.5;Karpas-707: 50.4;U-266/70: 41.7;U-266/84: 34.2;U-87 MG: 38.6" "Low region specificity" "Detected in many" "HPA031365, HPA040309" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nucleoplasm, Cytosol" "HPA031365: AB_10601332, HPA040309: AB_2676925" "unprognostic (6.05e-2)" "unprognostic (7.68e-2)" "unprognostic (4.24e-3)" "unprognostic (2.08e-2)" "unprognostic (6.94e-2)" "unprognostic (3.44e-1)" "unprognostic (3.20e-1)" "unprognostic (1.35e-1)" "unprognostic (4.27e-2)" "unprognostic (1.28e-3)" "unprognostic (7.10e-3)" "unprognostic (1.13e-1)" "unprognostic (1.23e-12)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (2.28e-1)" "unprognostic (2.32e-3)" 1.2 0.6 0.9 21.6 0.6 1.2 0.9 0.9 0.9 0.6 8.1 2.4 1.8 0.4 0.3 1.6 0.4 2.3 0.3 0.8 0.6 0.5 1.7 1.7 50.3 1.3 0.9 0.2 0.4 0.0 9.8 0.9 1.1 0.9 2.2 0.4 1.3 0.1 0.3 0.6 15.5 0.8 0.8 24.9 3.2 2.5 0.8 4.1 0.7 1.0 49.4 14.0 0.5 0.7 15.8 0.0 0.9 0.0 0.0 12.5 0.0 0.0 1.6 1.1 1.0 0.0 0.0 94.6 0.1 0.0 0.1 0.1 0.0 0.0 1.0 132.5 0.0 3.3 0.1 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 50.4 0.0 0.0 0.0 0.3 0.9 0.0 0.4 0.0 0.0 8.9 0.0 8.3 8.6 0.0 0.2 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.1 17.9 0.3 41.7 34.2 0.8 38.6 3.4 6.7 20.7 8.2 0.0 2.0 7.0 5.4 143.8 5.3 3.5 4.2 63.7 0.5 1.3 16.3 0.0 8.2 0.0 11.9 5.0 0.9 0.6 0.9 0.9 0.8 0.6 1.3 0.9 1.1 0.8 0.8 0.7 0.4 0.0 0.0 0.0 64.2 0.0 0.1 0.2 0.0 0.7 0.1 0.3 0.3 0.0 0.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 24.0 0.0 0.0 0.9 0.0 0.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.4 0.0 0.0 3.2 1.9 33.3 0.3 3.2 3.6 0.0 4.0 0.3 0.0 0.5 0.0 0.1 0.1 0.7 40.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 1.7 0.4 1.4 0.0 0.0 10.0 0.0 0.0 0.4 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 72.8;lymphoid tissue: 93.9" "Cell type enhanced" "Detected in many" "B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA071285: AB_2686379" "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favorable (7.18e-4)" 16.8 8.4 1.4 8.4 1.1 31.1 12.7 2.8 2.9 6.1 1.0 11.0 3.0 6.9 0.3 10.7 11.1 3.4 6.7 1.2 1.8 8.3 5.5 72.8 6.7 4.1 2.5 2.6 23.2 0.9 3.2 3.6 2.7 11.8 2.3 0.1 14.1 1.5 2.1 5.6 35.8 4.9 2.5 93.9 9.3 2.1 2.2 2.6 4.7 3.7 8.9 40.0 7.9 4.2 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 7.4 40.9 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 8.6 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 2.7 0.0 5.2 0.7 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.0 0.0 2.2 0.0 0.0 30.8 2.8 11.0 0.0 0.1 0.0 462.5 225.6 317.6 0.3 198.4 0.6 133.9 5.3 1.7 119.7 98.5 0.7 0.5 457.8 0.2 210.5 2.4 1.2 136.1 1.4 1.1 2.8 2.9 1.2 1.8 4.1 2.5 2.7 2.5 2.2 4.2 0.7 16.0 38.4 1.3 63.7 1.1 7.3 0.2 1.2 1.3 7.3 4.3 2.2 12.8 9.5 9.2 2.1 0.7 1.7 1.7 0.0 20.9 0.5 0.7 0.5 3.0 7.1 1.7 2.8 21.6 2.0 1.7 13.7 4.4 201.3 2.2 3.6 1.1 85.0 0.0 1.1 2.0 14.2 78.5 17.8 1.1 0.3 86.5 0.0 47.8 59.5 0.7 4.1 4.0 1.4 18.4 0.6 0.0 13.8 4.0 9.4 0.2 2.6 0.3 13.1 0.3 1.1 0.3 1.1 9.2 1.4 4.1 5.9 0.7 3.2 45.3 ANKRD13A "ANKRD13, NY-REN-25" ENSG00000076513 "Ankyrin repeat domain 13A" Q8IZ07 12 109999186-110039763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 205.4;HBF TERT88: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039488, HPA043218" Enhanced Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA039488: AB_10673612, HPA043218: AB_2678367" "unprognostic (1.54e-1)" "unprognostic (3.94e-3)" "unprognostic (5.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "prognostic favorable (7.70e-6)" "unprognostic (5.68e-2)" "unprognostic (1.31e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (9.71e-3)" "unprognostic (1.67e-1)" "unprognostic (2.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.13e-2)" "unprognostic (1.08e-1)" "unprognostic (5.29e-2)" 13.2 10.9 6.3 36.5 10.0 36.0 16.4 8.8 8.1 14.1 6.1 21.8 14.3 11.9 6.6 31.7 12.3 22.9 10.7 7.1 7.4 17.6 15.3 26.9 54.0 8.4 8.7 16.3 12.3 17.4 4.6 24.4 9.0 17.9 22.4 8.7 27.5 24.6 6.9 22.6 17.6 24.4 7.5 32.8 17.1 60.9 8.4 27.9 28.2 8.7 66.7 25.9 13.2 15.0 163.7 7.3 16.9 15.6 25.4 25.1 20.8 160.9 150.5 149.8 79.3 21.2 10.3 107.8 12.4 205.4 18.7 19.0 21.7 24.0 200.3 122.3 19.2 39.9 15.6 17.4 22.2 46.8 46.2 21.9 24.9 63.8 36.5 37.3 23.0 24.9 31.6 17.2 66.5 5.8 41.3 19.5 9.3 11.7 34.1 35.8 47.3 42.7 21.2 20.7 34.7 16.5 29.6 57.0 19.5 11.4 26.0 38.5 29.2 111.6 20.0 62.2 87.4 36.8 23.3 144.1 54.3 31.7 16.5 1.5 1.2 5.6 0.5 2.5 1.5 2.0 1.3 0.6 1.5 1.2 0.7 1.0 3.5 0.9 1.1 1.0 0.6 0.7 6.3 10.0 8.8 8.1 7.1 7.4 8.4 8.7 9.0 7.5 8.4 15.0 15.7 48.1 32.5 13.4 75.5 29.3 18.7 11.0 15.4 24.4 23.1 16.9 13.0 28.6 30.5 57.0 14.6 16.9 31.2 30.3 21.5 29.2 104.7 22.0 12.3 14.9 18.7 19.4 15.9 17.6 21.0 15.5 16.3 29.5 13.3 18.5 15.7 17.3 15.4 25.2 26.9 9.4 4.1 37.1 26.9 160.4 11.8 33.7 14.2 16.9 34.2 9.7 21.6 17.6 46.0 20.8 12.5 21.8 33.0 16.2 16.0 9.8 37.6 14.2 32.9 50.3 18.0 71.1 15.0 23.9 37.8 37.6 31.8 16.9 17.0 25.7 ANKRD44 PP6-ARS-B ENSG00000065413 "Ankyrin repeat domain 44" Q8N8A2 2 196967017-197311173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.5" "Cell type enhanced" "Detected in many" "B-cells: 153.3;Microglial cells: 390.7;NK-cells: 146.2;Oligodendrocyte precursor cells: 174.9;Oligodendrocytes: 199.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.4;HMC-1: 33.8;Karpas-707: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030122, HPA056549" Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nuclear speckles" "HPA030122: AB_10600980, HPA056549: AB_2683170" "unprognostic (3.64e-1)" "unprognostic (1.70e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-1)" "unprognostic (7.04e-5)" "unprognostic (1.97e-2)" "unprognostic (1.58e-3)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (8.25e-3)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-2)" 5.8 6.4 8.0 24.6 10.8 17.4 4.1 8.9 9.3 8.1 5.7 5.8 3.8 4.9 2.8 3.2 3.8 8.4 4.2 6.8 10.4 3.3 4.9 11.6 36.5 12.7 10.8 3.2 3.7 4.1 3.9 7.6 13.2 4.4 5.5 3.3 4.0 5.0 2.2 3.6 11.5 6.1 10.0 23.0 6.8 5.7 11.7 28.3 3.2 2.2 33.2 6.8 6.2 14.6 1.9 1.1 2.8 2.9 6.2 2.5 0.6 4.1 1.8 2.1 1.9 0.7 1.0 15.4 1.9 3.5 3.9 0.2 1.0 0.8 1.7 46.4 3.7 0.5 5.6 0.3 0.4 11.4 33.8 1.3 0.5 2.1 0.1 3.1 2.9 3.8 2.6 25.1 3.2 2.6 5.4 9.7 0.4 0.6 2.8 9.7 3.1 20.3 5.4 1.4 2.8 12.2 1.4 1.0 12.0 2.1 1.5 11.0 15.0 7.1 4.2 2.2 3.0 6.2 8.0 19.6 5.0 14.0 4.5 55.0 19.6 45.3 24.5 19.5 23.3 23.5 18.2 21.3 19.2 28.6 20.9 25.2 68.7 25.0 25.2 12.6 19.0 15.1 8.0 10.8 8.9 9.3 6.8 10.4 12.7 10.8 13.2 10.0 11.7 14.6 8.4 16.0 23.9 79.7 153.3 3.4 4.5 0.4 2.2 9.9 4.4 3.9 9.3 20.0 8.0 11.0 4.2 5.9 90.6 0.6 1.9 4.0 14.0 10.7 6.7 10.2 2.4 12.8 32.6 4.6 0.8 9.7 8.2 15.5 53.8 4.8 49.2 8.9 18.5 3.3 126.4 1.9 0.0 64.2 34.9 17.5 15.5 72.5 37.4 390.7 84.1 8.0 146.2 174.9 199.5 5.0 2.6 17.7 70.4 3.9 2.9 1.5 10.6 10.4 19.7 15.5 16.4 2.9 3.4 5.2 3.7 1.4 123.0 4.3 1.8 4.9 APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227726-57278105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 28.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011138 Approved Approved "Vesicles,Plasma membrane,Actin filaments,Cytosol" NA No 10000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Plasma membrane" "Actin filaments, Cytosol" "HPA011138: AB_1844959" "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (3.68e-2)" "unprognostic (2.31e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (5.55e-2)" "prognostic favorable (7.26e-5)" "unprognostic (3.99e-2)" "unprognostic (8.76e-2)" "unprognostic (1.12e-2)" "unprognostic (1.55e-1)" 15.6 11.6 9.5 14.8 9.7 15.1 18.9 12.9 11.3 17.1 6.8 14.2 12.6 17.1 10.6 16.9 11.7 13.0 24.7 9.7 11.3 16.5 12.9 13.6 16.7 9.8 10.1 22.7 29.6 25.1 7.8 14.3 10.1 15.0 14.0 13.5 15.2 14.4 44.2 20.1 14.6 15.3 10.4 15.8 15.2 8.0 10.2 18.9 19.8 26.6 19.6 13.4 11.9 10.7 30.2 12.9 12.2 45.4 21.2 29.7 26.2 15.5 9.5 15.4 17.8 14.9 17.5 47.3 6.2 24.6 24.7 5.9 33.7 27.3 26.6 36.1 15.0 27.6 19.5 16.1 22.7 59.6 19.1 21.8 24.3 19.3 21.3 31.3 25.3 30.2 9.0 30.0 17.8 10.4 48.7 15.4 19.5 21.6 21.7 1.7 49.1 26.1 27.7 16.7 12.5 26.5 21.1 32.3 21.0 16.7 15.7 39.6 23.4 25.1 17.5 37.4 29.9 27.0 41.8 33.2 27.4 29.1 17.1 2.0 5.3 3.8 3.7 4.5 4.9 17.9 3.8 3.3 10.9 28.3 3.3 2.5 1.4 7.4 3.6 18.0 1.9 2.7 9.5 9.7 12.9 11.3 9.7 11.3 9.8 10.1 10.1 10.4 10.2 10.7 82.9 51.3 45.5 19.6 106.6 52.9 47.3 46.9 83.6 40.5 67.2 92.8 100.1 47.1 47.4 42.3 31.3 46.9 70.9 29.0 58.7 58.6 42.5 35.4 92.8 66.2 45.6 20.0 49.7 60.3 44.7 68.6 40.2 59.4 23.4 60.8 40.0 44.1 52.2 52.2 50.4 36.2 42.7 68.6 50.6 22.1 73.0 71.0 19.6 33.7 87.8 56.6 56.7 43.2 62.2 51.7 25.5 76.0 62.8 38.7 41.0 58.8 18.1 55.4 52.6 94.3 61.2 64.9 44.2 105.7 69.6 28.0 45.4 73.7 49.1 25.8 ARHGAP4 "C1, KIAA0131, p115, RhoGAP4, SrGAP4" ENSG00000089820 "Rho GTPase activating protein 4" P98171 X 153907367-153934999 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 119.1;lymphoid tissue: 120.9" "Cell type enhanced" "Detected in many" "B-cells: 65.3;dendritic cells: 70.0;Hofbauer cells: 86.6;Kupffer cells: 77.2;Macrophages: 76.0;NK-cells: 70.0;T-cells: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 103.0;HL-60: 76.7;Karpas-707: 90.8;MOLT-4: 93.0;RPMI-8226: 180.7;THP-1: 83.7;U-698: 90.4;U-937: 79.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA000301, HPA001012, HPA001083" Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA000301: , HPA001012: AB_1078201, HPA001083: AB_1078199" "unprognostic (3.54e-2)" "prognostic favorable (3.94e-5)" "prognostic unfavorable (1.97e-5)" "unprognostic (5.79e-2)" "unprognostic (9.42e-2)" "prognostic favorable (3.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.39e-1)" "unprognostic (3.27e-1)" "unprognostic (1.37e-1)" "unprognostic (7.81e-3)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (8.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" 20.0 12.5 5.2 52.2 5.4 119.1 13.4 6.9 6.5 9.9 15.0 18.6 14.2 9.7 3.1 7.0 12.9 14.4 10.3 5.7 6.3 22.6 8.6 36.2 73.8 10.9 8.3 5.4 5.9 1.7 8.6 21.2 9.3 11.1 6.9 1.2 9.2 3.8 4.3 5.0 49.7 6.5 8.2 120.9 12.6 7.2 8.5 42.7 10.9 1.5 33.7 11.6 9.2 10.0 1.5 0.6 1.0 5.9 0.2 0.0 2.5 1.0 0.4 0.1 0.2 0.4 42.8 103.0 5.9 0.1 0.8 1.2 4.6 0.2 0.0 27.8 3.4 44.4 0.5 1.7 3.6 76.7 59.7 0.2 0.4 0.0 0.3 0.5 9.1 22.4 0.5 90.8 0.5 4.6 93.0 1.5 3.7 0.4 0.3 44.6 12.0 180.7 0.4 0.7 8.4 12.1 0.9 2.1 0.9 1.2 19.0 83.7 1.9 0.3 1.3 0.9 0.5 60.1 55.8 90.4 0.7 79.9 0.2 10.9 26.1 35.4 26.2 42.4 18.6 18.0 18.8 21.1 25.5 16.9 17.4 17.4 22.4 16.0 59.4 31.6 23.5 26.1 5.2 5.4 6.9 6.5 5.7 6.3 10.9 8.3 9.3 8.2 8.5 10.0 16.0 9.6 22.7 2.6 65.3 3.4 0.6 0.2 0.0 13.7 2.4 6.1 48.3 1.5 2.7 18.4 4.2 1.9 70.0 9.5 5.9 0.9 0.1 2.4 1.4 13.0 4.8 11.3 2.1 0.6 1.9 3.5 7.1 1.5 34.2 7.7 4.2 0.5 86.6 3.3 1.4 6.6 0.0 77.2 31.5 0.2 0.9 76.0 10.6 19.7 42.5 1.9 70.0 2.0 0.7 0.2 0.5 0.0 32.9 0.5 3.0 0.8 8.7 4.6 0.0 7.1 2.6 0.7 5.2 1.6 1.7 1.4 69.5 1.1 5.0 0.4 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 ARPC3 "ARC21, p21-Arc" ENSG00000111229 "Actin related protein 2/3 complex subunit 3" O15145 12 110434823-110450422 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006550 Approved Uncertain Nucleoplasm NA NA 3800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA006550: AB_1854869" "unprognostic (1.83e-1)" "unprognostic (4.21e-3)" "unprognostic (4.15e-1)" "unprognostic (4.26e-3)" "unprognostic (2.89e-1)" "unprognostic (1.11e-3)" "unprognostic (1.10e-2)" "unprognostic (6.71e-2)" "unprognostic (2.89e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (9.96e-2)" "prognostic unfavorable (2.22e-11)" "unprognostic (3.00e-1)" "unprognostic (5.83e-2)" "unprognostic (2.05e-2)" "unprognostic (1.79e-3)" 196.5 205.3 160.2 365.7 167.7 774.3 213.5 160.2 228.2 205.5 165.9 324.0 259.5 151.6 298.3 367.1 162.2 253.1 153.0 167.3 171.5 241.6 262.4 264.7 578.8 172.9 166.9 107.2 171.6 174.8 163.6 276.6 170.8 166.9 344.1 60.4 205.0 152.1 106.7 156.5 258.2 206.6 169.4 366.3 263.3 106.9 165.1 343.3 184.2 102.5 573.7 355.8 206.5 180.5 452.0 360.8 307.0 196.4 318.3 600.2 411.5 476.0 550.1 594.6 578.6 392.9 350.1 654.7 359.3 559.7 354.4 340.1 343.9 520.7 647.7 377.7 415.6 562.1 146.6 385.1 519.7 565.6 842.4 422.6 555.3 375.3 347.8 736.2 756.3 434.5 366.2 170.3 746.3 365.6 661.6 1390.3 302.7 525.8 428.6 510.9 181.5 559.4 1050.5 581.0 346.6 342.2 334.0 464.7 427.1 453.8 757.8 933.8 630.0 350.5 195.7 312.9 349.9 332.7 507.0 914.8 458.0 568.1 425.1 1313.6 1022.6 1660.3 352.4 1182.3 322.2 692.3 361.1 398.7 987.2 604.5 267.0 349.5 1607.5 418.3 1417.4 632.7 619.8 1547.5 160.2 167.7 160.2 228.2 167.3 171.5 172.9 166.9 170.8 169.4 165.1 180.5 316.2 189.1 239.5 16.6 619.4 159.5 315.8 810.1 145.1 36.1 222.3 252.2 52.2 208.8 555.8 268.5 12.5 538.2 582.4 473.2 579.2 636.3 131.2 373.6 241.1 269.0 274.1 244.0 32.4 535.1 824.0 199.0 190.6 459.6 491.8 245.8 227.7 165.5 1432.0 53.8 25.1 538.9 537.1 918.9 781.2 45.3 172.4 935.9 240.1 45.9 1221.8 184.1 545.8 23.6 41.6 630.2 665.2 157.6 352.5 313.5 422.2 777.0 407.3 35.6 249.8 108.4 329.6 209.8 200.1 365.5 171.9 721.6 462.6 323.3 401.1 629.3 ATG16L2 "ATG16B, FLJ00012, WDR80" ENSG00000168010 "Autophagy related 16 like 2" Q8NAA4 11 72814406-72843674 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 136.8;lymphoid tissue: 129.0" "Cell type enhanced" "Detected in many" "Paneth cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 45.4;neutrophil: 59.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045444, HPA050312" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA045444: AB_2679324, HPA050312: AB_2681082" "unprognostic (7.20e-3)" "unprognostic (1.16e-1)" "unprognostic (1.54e-1)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (1.31e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" "prognostic favorable (7.06e-4)" "unprognostic (2.49e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (1.74e-1)" "unprognostic (4.38e-2)" "unprognostic (1.08e-1)" "unprognostic (4.83e-2)" 20.2 18.1 18.1 33.0 19.2 136.8 14.9 20.2 24.1 21.6 16.2 20.4 10.8 14.6 7.5 26.1 22.1 18.9 20.8 18.0 16.0 20.1 18.5 41.2 34.3 18.9 17.7 23.4 15.1 6.3 13.7 10.2 18.0 14.4 17.0 2.9 13.6 8.2 7.7 72.9 34.0 15.0 15.3 129.0 17.7 6.5 21.1 9.7 15.9 7.4 25.2 18.9 22.2 20.9 2.7 2.5 7.5 5.9 8.7 7.2 4.6 6.1 5.9 2.9 4.4 3.1 6.4 18.3 4.0 7.7 5.3 5.2 0.9 20.1 5.0 14.2 3.0 14.5 14.4 5.1 6.4 18.8 58.2 6.9 2.7 6.6 8.0 32.2 9.0 32.7 1.9 24.1 3.4 9.1 22.5 32.0 1.1 12.0 2.9 10.6 5.5 8.6 9.7 9.2 5.5 4.4 2.6 13.2 5.8 5.9 6.6 25.5 12.6 7.9 2.9 14.4 5.0 11.0 2.9 8.1 3.5 16.4 4.5 5.9 16.3 45.4 2.7 9.3 2.7 2.6 3.9 5.4 10.9 4.6 2.2 2.6 59.6 5.2 11.8 1.7 4.0 4.0 18.1 19.2 20.2 24.1 18.0 16.0 18.9 17.7 18.0 15.3 21.1 20.9 19.5 6.4 14.4 11.4 37.6 16.7 5.1 6.1 10.2 3.6 8.7 9.0 5.0 4.3 6.2 5.5 2.1 9.6 29.0 13.0 0.0 5.0 0.8 8.9 12.0 12.7 13.1 9.9 14.0 1.0 3.7 7.1 17.9 7.9 22.9 10.6 18.9 3.8 16.2 5.0 11.1 9.1 8.2 48.5 18.1 2.1 10.2 45.7 3.6 23.4 39.2 4.4 30.9 18.1 9.7 2.7 59.1 7.9 17.3 2.5 8.3 2.5 8.1 3.5 0.0 8.8 11.4 4.9 13.4 15.7 17.3 12.3 21.3 7.2 14.0 6.0 BANK1 "BANK, FLJ20706" ENSG00000153064 "B cell scaffold protein with ankyrin repeats 1" Q8NDB2 4 101411286-102074812 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.2;lymphoid tissue: 96.4" "Cell type enriched" "Detected in many" 10 "B-cells: 455.9" "Cancer enhanced" "Detected in many" "prostate cancer: 6.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 14 "memory B-cell: 310.4;naive B-cell: 253.0" "Lineage enriched" "Detected in many" 16 "B-cells: 310.4" "Cell line enhanced" "Detected in some" "Daudi: 13.6;HEL: 10.6;HL-60: 9.6;U-266/70: 31.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037002 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 19000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA037002: AB_10672383" "unprognostic (1.59e-2)" "unprognostic (2.08e-2)" "unprognostic (6.43e-2)" "unprognostic (1.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.73e-2)" "unprognostic (4.89e-2)" "unprognostic (1.62e-2)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (4.25e-2)" "unprognostic (7.89e-2)" "unprognostic (2.80e-1)" "unprognostic (2.18e-1)" "unprognostic (2.75e-2)" "unprognostic (6.09e-3)" "unprognostic (1.75e-1)" 8.5 3.6 0.6 35.1 0.6 6.2 2.2 1.5 0.9 2.3 0.2 2.8 2.4 0.8 3.2 0.8 2.3 3.0 0.7 0.5 0.7 3.2 0.3 8.1 82.2 0.8 0.8 0.1 0.5 0.4 1.5 0.8 0.9 5.8 3.3 0.2 2.4 4.7 0.1 0.7 24.2 1.0 0.9 56.1 7.4 3.0 1.0 9.7 12.9 0.2 96.4 7.6 0.7 0.6 0.0 3.0 0.0 0.0 3.4 1.4 0.1 0.1 0.1 0.4 0.6 0.1 4.6 13.6 1.2 0.0 0.0 0.2 0.1 1.5 0.4 0.0 0.0 10.6 2.6 0.0 0.1 9.6 0.0 0.6 0.4 0.0 0.0 1.2 0.1 0.0 0.1 4.0 0.6 0.5 0.0 0.6 0.0 0.4 5.7 0.2 0.6 0.0 0.4 6.1 2.6 0.0 0.3 0.2 0.0 0.1 0.5 2.5 1.3 0.0 0.6 0.0 0.0 31.0 0.0 2.2 0.1 5.3 0.0 10.8 1.7 19.7 0.4 0.5 0.1 310.4 0.1 0.2 10.5 253.0 0.1 0.1 0.9 1.5 0.2 5.2 0.2 11.3 0.6 0.6 1.5 0.9 0.5 0.7 0.8 0.8 0.9 0.9 1.0 0.6 3.5 44.8 27.1 6.8 455.9 0.1 2.2 0.5 0.0 0.2 1.7 0.4 0.5 0.0 10.0 3.7 0.0 2.1 5.8 0.0 0.0 0.2 2.8 13.1 1.0 1.3 0.0 6.1 7.3 0.2 0.6 1.4 6.1 15.2 1.3 0.1 0.0 0.1 1.5 0.0 1.6 0.4 2.0 2.9 25.1 2.0 0.0 13.0 5.4 4.7 2.8 1.8 1.0 1.0 1.3 4.1 1.3 0.4 13.7 4.4 0.2 4.2 2.2 0.1 0.0 0.1 0.8 1.9 5.6 0.8 1.1 0.3 12.9 2.1 1.1 4.3 BEND5 "C1orf165, FLJ11588" ENSG00000162373 "BEN domain containing 5" Q7L4P6 1 48727519-48776969 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Proximal tubular cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 6.5;naive B-cell: 8.0" "Lineage enriched" "Detected in many" 5 "B-cells: 8.0" "Cell line enhanced" "Detected in some" "AF22: 3.4;HDLM-2: 11.7;JURKAT: 4.5;MOLT-4: 4.8;REH: 6.5;SH-SY5Y: 2.9" "Low region specificity" "Detected in many" "HPA054347, HPA058007" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" Cytosol "HPA054347: AB_2682456, HPA058007: AB_2683577" "prognostic favorable (2.50e-5)" "unprognostic (1.36e-2)" "unprognostic (7.19e-3)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (4.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.41e-1)" "unprognostic (6.02e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.32e-2)" "unprognostic (4.28e-2)" "unprognostic (2.37e-3)" "unprognostic (3.35e-2)" "unprognostic (9.68e-2)" "prognostic favorable (8.30e-6)" 1.7 1.9 5.1 0.7 5.1 1.0 1.8 4.1 7.4 2.8 4.1 3.4 0.4 2.0 1.5 0.6 2.5 2.0 1.6 5.1 4.3 3.4 0.1 0.9 2.1 6.3 5.0 4.4 1.7 1.8 3.4 0.3 6.4 1.5 0.4 3.7 1.0 1.2 2.6 0.8 1.6 0.7 4.1 2.7 1.7 1.0 4.8 4.8 1.8 1.7 1.4 2.2 1.7 5.3 0.0 0.0 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 4.8 0.2 2.6 0.0 0.0 6.5 1.1 0.0 0.0 1.2 1.1 2.9 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.2 1.7 8.0 1.6 1.0 0.2 1.2 0.0 1.7 0.0 0.4 5.1 5.1 4.1 7.4 5.1 4.3 6.3 5.0 6.4 4.1 4.8 5.3 8.7 6.4 3.1 0.0 17.2 1.9 4.6 4.6 1.8 13.3 4.0 16.9 8.6 8.6 6.1 5.5 16.7 0.3 0.6 0.5 54.8 6.4 8.9 2.7 1.9 6.9 12.1 0.8 0.0 1.8 0.5 8.4 2.6 1.3 1.3 10.2 4.6 0.2 0.3 8.4 0.0 0.8 2.0 0.6 4.4 7.1 13.1 1.5 3.6 0.0 0.5 22.7 0.0 0.0 0.0 2.6 4.5 21.4 7.6 1.1 0.2 30.2 6.4 17.8 6.6 6.8 5.6 3.7 9.1 0.3 2.3 0.1 2.8 11.4 1.6 1.9 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564599 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 39.1;lymphoid tissue: 46.7" "Cell type enriched" "Detected in some" 11 "B-cells: 116.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 183.4;naive B-cell: 131.5" "Lineage enriched" "Detected in many" 5 "B-cells: 183.4" "Cell line enhanced" "Detected in some" "Daudi: 106.6;REH: 29.9;RPMI-8226: 38.5;U-698: 48.6;U-87 MG: 22.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB005093, HPA069571" Approved Uncertain Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "CAB005093: AB_2274756, HPA069571: AB_2732137" "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.1 0.0 9.1 0.0 2.6 0.2 0.0 0.0 0.0 0.0 2.6 0.5 0.1 0.0 1.2 0.2 0.5 0.1 0.0 0.0 1.2 0.7 0.8 29.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.0 0.7 0.0 0.3 0.0 39.1 0.1 0.0 46.7 2.1 0.1 0.0 2.5 1.2 0.0 27.9 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 29.9 0.0 38.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 5.4 10.2 48.6 22.7 0.0 0.0 0.2 0.1 0.2 2.0 0.0 37.9 183.4 1.4 4.6 0.1 131.5 0.9 0.4 0.7 0.1 0.1 17.5 1.8 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 116.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.1 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 4.0 0.1 0.1 0.0 BLNK "BASH, bca, BLNK-s, Ly57, SLP-65, SLP65" ENSG00000095585 "B cell linker" Q8WV28 10 96189171-96271587 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 70.5" "Cell type enhanced" "Detected in many" "B-cells: 94.2;dendritic cells: 64.0;Microglial cells: 157.4;Plasma cells: 80.4;Proximal enterocytes: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "memory B-cell: 161.2;naive B-cell: 140.5;plasmacytoid DC: 231.5" "Group enriched" "Detected in many" 101 "B-cells: 161.2;dendritic cells: 231.5" "Group enriched" "Detected in some" 6 "Daudi: 68.7;REH: 168.4;RPMI-8226: 94.4;U-698: 251.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009333, CAB016291, HPA038309, HPA038310" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "CAB009333: AB_2290422, CAB016291: AB_626752, HPA038309: AB_2675945, HPA038310: AB_2675946" "unprognostic (4.86e-2)" "unprognostic (6.05e-3)" "unprognostic (1.00e-2)" "unprognostic (2.73e-2)" "unprognostic (2.29e-1)" "unprognostic (1.63e-3)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (8.94e-2)" "unprognostic (3.73e-1)" "unprognostic (1.84e-2)" "unprognostic (5.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.46e-3)" "prognostic favorable (2.67e-6)" 2.2 3.2 3.8 27.5 3.4 10.1 6.3 2.4 4.1 7.1 13.9 16.9 38.9 2.4 30.1 39.9 6.1 10.8 1.0 3.5 5.1 28.5 39.2 6.6 57.6 4.7 4.0 1.5 12.1 17.4 1.8 6.4 5.0 7.3 18.2 1.4 10.9 13.2 0.5 8.0 34.0 3.0 3.8 54.0 29.2 1.3 4.9 10.6 11.6 1.1 70.5 9.9 15.8 5.2 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.2 68.7 0.4 0.0 0.3 0.6 0.1 0.8 0.1 5.5 0.2 0.3 0.3 0.1 0.0 0.1 1.4 0.1 8.7 0.0 0.0 0.1 0.0 0.8 0.3 6.4 0.0 0.7 0.4 0.2 0.2 0.2 0.0 168.4 0.3 94.4 0.9 13.0 0.3 0.3 0.2 15.1 0.1 0.2 23.7 1.1 0.2 0.2 0.8 0.1 0.2 5.4 0.4 251.4 0.1 0.5 0.1 0.3 1.6 0.2 0.3 1.3 0.1 161.2 0.3 0.2 20.6 140.5 0.1 0.1 1.1 1.9 0.1 231.5 0.6 8.1 3.8 3.4 2.4 4.1 3.5 5.1 4.7 4.0 5.0 3.8 4.9 5.2 0.4 6.4 7.7 0.7 94.2 1.1 21.0 13.1 21.1 0.0 4.1 3.4 1.2 30.0 7.3 40.5 0.0 23.0 64.0 9.2 27.4 14.6 3.1 14.4 1.9 0.3 4.9 5.3 1.0 13.8 17.5 0.7 35.7 22.9 1.3 0.0 2.9 27.8 22.8 0.0 1.3 19.4 30.5 9.0 13.8 1.1 0.3 18.2 1.8 157.4 4.8 0.0 0.0 2.5 0.9 4.4 22.4 0.0 80.4 5.1 64.6 2.3 3.4 0.0 6.6 0.3 0.7 1.6 0.1 34.7 1.4 41.5 3.6 0.5 22.5 23.8 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 BTLA "BTLA1, CD272" ENSG00000186265 "B and T lymphocyte associated" Q7Z6A9 3 112463966-112499472 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 28.6" "Cell type enriched" "Detected in some" 4 "B-cells: 66.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 65.0;naive B-cell: 96.5;plasmacytoid DC: 24.9" "Group enriched" "Detected in many" 4 "B-cells: 96.5;dendritic cells: 24.9" "Cell line enhanced" "Detected in single" "U-698: 2.0" "Not detected" "Not detected" "HPA047211, HPA062029" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA047211: AB_2679983, HPA062029: AB_2684665" "unprognostic (1.13e-3)" "unprognostic (2.13e-3)" "unprognostic (5.79e-4)" "unprognostic (1.01e-4)" "unprognostic (7.08e-2)" "unprognostic (7.74e-6)" "unprognostic (6.20e-3)" "unprognostic (7.59e-3)" "unprognostic (5.98e-2)" "unprognostic (1.53e-5)" "unprognostic (2.33e-2)" "unprognostic (1.23e-1)" "unprognostic (1.57e-5)" "unprognostic (2.57e-1)" "unprognostic (2.46e-2)" "unprognostic (1.65e-1)" "unprognostic (1.42e-2)" 0.4 0.3 0.0 11.2 0.0 2.1 1.9 0.1 0.4 0.5 0.0 1.7 1.6 0.3 0.1 0.6 0.3 1.1 0.2 0.0 0.0 0.3 0.6 0.9 26.4 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.1 0.4 1.6 0.2 1.3 0.1 0.1 0.1 3.1 0.4 0.0 10.8 3.0 0.1 0.0 7.7 0.3 0.1 28.6 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 0.1 0.0 11.2 0.0 8.3 65.0 13.6 6.5 4.6 96.5 12.7 12.6 0.5 0.3 0.1 24.9 3.4 6.5 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 66.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.3 0.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.5 1.3 0.0 0.4 0.2 0.1 0.0 0.4 0.0 0.0 1.3 4.7 3.6 0.0 1.6 7.2 0.0 1.9 0.0 0.0 1.0 0.3 0.0 0.0 0.0 15.9 0.0 0.0 0.2 0.7 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.3 0.1 8.6 0.0 0.0 0.1 BTN2A2 "BT2.2, BTF2, BTN2.2" ENSG00000124508 "Butyrophilin subfamily 2 member A2" Q8WVV5 6 26383096-26394874 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 30.3;Plasma cells: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 72.8;U-266/70: 58.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051504 Uncertain Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA051504: AB_2681510" "prognostic favorable (1.01e-4)" "unprognostic (4.93e-3)" "unprognostic (1.37e-2)" "unprognostic (6.78e-2)" "unprognostic (9.26e-2)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.04e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (1.93e-1)" "unprognostic (1.73e-2)" "unprognostic (3.45e-1)" "unprognostic (6.54e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" 7.2 13.5 5.4 21.9 6.9 4.3 8.7 14.4 6.0 7.9 21.2 8.0 7.2 10.2 7.5 5.1 8.4 8.5 4.9 6.8 5.9 7.5 6.1 16.2 32.1 7.5 6.9 10.4 5.2 17.5 5.7 4.0 7.8 8.3 10.5 2.9 12.1 6.8 2.8 11.0 11.3 10.9 6.5 21.8 10.4 6.1 6.2 15.2 7.5 4.2 36.6 8.2 6.9 6.9 10.6 6.6 13.2 14.2 4.4 6.8 0.9 11.4 29.7 17.4 30.0 4.2 4.1 9.6 12.1 20.5 14.1 9.5 10.7 8.7 23.1 29.9 17.9 15.0 13.2 8.4 9.1 3.4 5.1 14.5 2.7 33.5 11.3 20.7 16.3 18.5 12.3 72.8 7.9 4.6 12.1 4.4 5.0 0.4 6.6 28.1 18.7 29.8 12.7 5.9 12.6 17.6 7.4 2.8 31.1 7.5 13.5 6.6 19.5 6.4 7.3 5.6 17.7 58.9 38.8 16.9 6.4 13.4 16.3 2.1 13.7 2.4 6.1 14.6 5.8 24.1 5.0 5.7 23.9 29.4 4.1 5.1 12.4 8.7 6.3 9.7 10.3 7.9 5.4 6.9 14.4 6.0 6.8 5.9 7.5 6.9 7.8 6.5 6.2 6.9 8.1 9.6 12.6 0.0 30.3 3.8 7.3 6.5 6.2 0.6 5.2 5.1 2.5 2.8 8.5 3.7 0.0 2.3 15.0 0.6 0.0 8.6 0.4 8.8 4.5 13.1 1.8 3.6 0.0 5.6 0.8 5.0 3.6 7.5 19.6 9.6 6.1 3.8 8.4 0.0 0.0 7.8 12.2 16.0 24.2 0.6 6.5 17.1 7.2 0.0 15.4 14.3 7.2 0.0 0.0 8.3 0.8 4.9 30.7 6.4 2.6 2.3 10.2 0.7 0.0 5.0 4.4 0.3 1.5 4.5 4.5 1.0 10.0 10.6 2.1 4.2 C12orf66 FLJ32549 ENSG00000174206 "Chromosome 12 open reading frame 66" Q96MD2 12 64186316-64222296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046743, HPA052855" Uncertain Supported "Lysosomes,Cytokinetic bridge" Yes No "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Lysosomes "Cytokinetic bridge" "HPA046743: AB_2679782, HPA052855: AB_2681973" "unprognostic (7.44e-3)" "unprognostic (2.38e-1)" "unprognostic (6.20e-2)" "unprognostic (2.70e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "unprognostic (3.45e-2)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (7.46e-2)" "unprognostic (4.07e-2)" 2.9 4.2 3.6 3.4 5.3 1.7 5.4 4.0 4.8 2.8 1.9 2.8 3.1 2.6 4.8 4.2 3.9 2.5 2.3 3.5 4.3 5.5 8.6 2.8 4.9 4.0 4.4 3.9 5.2 5.7 2.6 2.1 4.5 2.3 3.1 1.6 2.9 2.3 4.4 5.6 2.5 2.3 3.7 5.0 3.0 3.4 4.3 3.3 5.6 3.2 4.8 2.6 3.0 6.8 5.5 8.7 1.6 4.7 4.3 7.2 4.5 3.0 3.7 4.4 2.7 2.7 4.3 17.4 4.1 2.4 7.1 6.3 6.9 5.3 4.7 13.3 4.6 6.3 2.1 2.5 5.6 6.9 3.6 5.6 9.0 5.7 10.3 5.0 3.2 12.0 8.8 11.3 4.4 10.6 7.9 6.0 7.7 6.5 6.8 4.0 4.9 13.4 6.6 6.4 3.8 3.8 4.9 6.7 4.8 4.2 10.8 4.4 2.5 4.4 2.9 4.4 2.9 14.9 13.2 9.7 6.6 5.9 5.0 0.5 2.6 0.2 3.3 2.6 5.7 8.5 6.4 5.0 4.3 7.2 8.7 8.4 0.2 4.0 1.8 3.1 10.8 4.2 3.6 5.3 4.0 4.8 3.5 4.3 4.0 4.4 4.5 3.7 4.3 6.8 3.4 3.2 2.7 5.5 9.3 2.4 8.8 3.4 7.4 2.1 5.9 4.1 2.7 7.2 5.5 9.2 2.1 6.3 4.0 1.9 9.8 4.1 9.2 3.3 4.0 3.9 4.2 3.4 7.1 5.2 3.9 3.5 7.1 3.6 1.3 3.6 1.8 10.8 4.9 0.0 5.5 2.7 4.1 6.3 2.6 7.3 4.7 4.3 1.8 1.0 2.1 2.5 1.0 3.5 17.4 2.6 2.6 1.9 2.8 4.7 2.1 12.9 2.4 1.6 0.0 7.4 2.8 4.4 8.8 6.9 4.3 1.8 5.8 4.3 3.7 4.3 C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA002569: AB_1078334" "prognostic favorable (5.05e-4)" "unprognostic (1.31e-2)" "unprognostic (2.97e-2)" "unprognostic (2.23e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (4.86e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (7.11e-2)" 8.3 4.8 6.5 5.7 7.7 12.6 8.2 6.7 7.0 11.2 8.5 8.8 7.4 8.7 11.4 7.4 9.5 9.2 5.6 6.2 7.3 11.1 8.9 6.7 10.1 7.7 7.2 10.3 9.6 8.3 6.5 5.0 7.5 9.6 9.6 4.4 8.0 5.7 6.7 18.3 8.1 6.8 6.7 10.6 8.3 4.0 7.2 15.7 11.5 7.9 10.5 8.6 8.3 9.5 5.7 10.5 8.8 12.3 13.9 30.8 12.2 6.6 10.2 5.1 6.7 6.6 16.5 16.0 6.1 6.0 7.2 11.8 5.4 16.6 4.7 6.3 3.8 10.1 14.0 15.3 12.1 7.4 8.3 22.4 12.8 7.6 9.6 18.5 9.6 10.1 11.1 3.4 5.3 16.3 9.5 13.6 3.0 12.3 7.3 15.1 8.4 9.8 6.7 8.6 31.8 13.8 8.8 8.4 9.0 9.4 13.0 12.8 5.5 9.6 12.7 4.3 6.7 11.9 3.6 11.0 6.6 9.1 10.0 12.2 7.7 22.9 8.1 7.4 7.2 10.4 6.5 8.5 9.1 10.0 9.8 9.4 11.2 10.4 13.0 6.3 13.4 7.1 6.5 7.7 6.7 7.0 6.2 7.3 7.7 7.2 7.5 6.7 7.2 9.5 3.1 9.6 1.1 14.7 8.7 3.1 4.1 4.6 10.2 1.4 4.0 4.1 3.3 1.5 2.6 0.0 4.2 4.3 7.8 3.7 7.9 3.9 0.8 3.3 2.6 3.3 15.7 6.5 3.4 3.0 5.7 3.9 7.7 3.0 7.0 4.7 1.4 1.5 3.8 0.0 3.4 6.3 4.1 5.5 2.5 1.5 4.4 3.4 5.4 9.4 1.9 4.1 7.2 7.1 9.9 3.1 7.3 4.1 5.2 1.9 4.6 3.6 4.6 2.0 6.6 3.8 3.7 2.9 8.2 5.3 1.6 3.0 5.2 4.1 5.1 2.5 C16orf74 MGC17624 ENSG00000154102 "Chromosome 16 open reading frame 74" Q96GX8 16 85690084-85751129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.7" "Cell type enhanced" "Detected in many" "B-cells: 47.4;Basal prostatic cells: 56.7;Bipolar cells: 55.8;Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 87.8;Syncytiotrophoblasts: 74.3;Urothelial cells: 55.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 96.1;hTCEpi: 80.8;T-47d: 84.5" HPA049367 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Plasma membrane" Centrosome "HPA049367: AB_2680730" "unprognostic (1.16e-1)" "unprognostic (2.21e-2)" "unprognostic (6.74e-3)" "unprognostic (2.15e-3)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.08e-3)" "unprognostic (4.22e-3)" "prognostic unfavorable (4.08e-4)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (3.40e-1)" "unprognostic (1.76e-3)" "unprognostic (2.51e-1)" "unprognostic (3.55e-1)" "unprognostic (2.15e-2)" "unprognostic (9.07e-3)" 3.6 0.7 8.4 4.3 8.5 8.9 6.5 6.8 12.0 9.5 7.8 3.1 1.4 1.5 2.0 9.4 1.5 2.2 2.2 12.2 7.4 2.5 1.1 2.2 8.4 7.5 7.4 0.8 1.8 7.5 1.3 6.7 7.0 9.2 1.1 27.7 4.2 7.3 0.5 9.0 5.6 0.9 6.7 16.0 2.9 2.1 7.6 1.4 5.0 0.3 6.4 17.2 14.5 7.4 35.3 11.5 0.4 4.7 5.1 5.6 14.1 4.2 5.6 13.1 3.7 8.9 32.1 0.3 47.2 3.3 5.5 49.4 2.0 96.1 7.4 0.0 7.6 0.0 5.3 0.9 13.9 1.0 0.0 12.2 80.8 12.6 54.7 9.8 43.4 5.8 0.0 0.2 0.4 29.6 0.0 54.0 2.9 37.7 32.6 1.4 0.0 2.8 0.1 39.5 10.7 2.8 17.5 8.9 9.1 3.6 84.5 14.9 44.8 8.4 22.0 3.8 12.7 11.7 9.3 40.0 0.0 12.6 1.7 0.1 16.8 21.8 1.3 6.3 4.4 46.7 8.8 7.0 18.3 49.4 14.5 9.3 6.6 7.8 2.0 0.3 18.0 10.8 8.4 8.5 6.8 12.0 12.2 7.4 7.5 7.4 7.0 6.7 7.6 7.4 10.1 3.2 1.1 6.5 47.4 9.3 56.7 23.8 8.0 55.8 19.0 20.3 1.8 1.5 9.8 1.8 58.4 45.8 3.4 0.1 3.9 3.0 1.7 4.4 4.6 7.2 0.0 0.8 0.4 1.1 19.7 5.7 1.5 4.1 0.0 0.5 2.5 0.0 5.0 15.2 0.4 0.0 8.2 1.2 2.9 0.4 3.4 2.5 19.6 1.0 5.2 18.8 4.1 1.5 0.8 3.2 0.0 3.4 44.2 36.5 0.0 2.4 3.9 87.8 0.0 0.3 2.5 0.9 8.4 8.5 7.0 74.3 3.7 1.5 0.2 55.7 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD19 ENSG00000177455 "CD19 molecule" P15391 16 28931965-28939342 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 33.0;lymphoid tissue: 75.3" "Cell type enhanced" "Detected in some" "B-cells: 135.3;Early spermatids: 38.2;Plasma cells: 30.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 80 "memory B-cell: 138.2;naive B-cell: 172.1" "Lineage enriched" "Detected in many" 89 "B-cells: 172.1" "Cell line enhanced" "Detected in some" "Daudi: 143.3;REH: 77.1;U-698: 33.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB016110 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB016110: AB_626952" "unprognostic (3.27e-3)" "unprognostic (1.19e-3)" "unprognostic (6.63e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-3)" "unprognostic (3.11e-5)" "unprognostic (2.61e-1)" "unprognostic (6.96e-3)" "unprognostic (1.29e-2)" "unprognostic (4.29e-3)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.41e-6)" "unprognostic (2.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (2.07e-1)" 0.6 0.1 0.0 28.5 0.1 6.2 0.1 0.9 0.4 0.1 0.0 2.0 0.9 0.2 0.1 0.9 0.2 0.9 0.1 0.0 0.0 0.7 0.3 0.5 72.1 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 1.6 0.1 1.2 0.1 0.0 0.0 33.0 0.2 0.0 72.7 3.9 3.8 0.2 5.7 1.2 0.0 75.3 2.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 77.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 33.0 0.0 0.1 0.0 1.9 0.2 0.2 0.0 0.3 0.0 138.2 0.1 0.0 0.3 172.1 0.4 0.1 1.3 0.3 0.4 0.2 0.0 7.2 0.0 0.1 0.9 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.3 0.2 0.0 0.6 0.0 135.3 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 1.5 0.2 0.0 0.0 38.2 1.5 0.0 1.0 0.0 0.8 0.0 0.0 0.8 0.8 0.5 0.1 0.0 0.4 1.4 0.3 1.7 0.0 0.0 0.1 0.0 0.8 0.6 7.9 0.3 1.1 3.6 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.1 0.7 30.5 0.2 0.3 0.1 0.5 0.1 0.0 0.1 0.1 7.4 4.2 0.0 0.0 0.7 2.4 0.6 0.5 0.1 CD1D ENSG00000158473 "CD1d molecule" P15813 1 158178030-158186427 "Cancer-related genes, CD markers, Predicted membrane proteins" "Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 18.2;liver: 15.3;lymphoid tissue: 23.9" "Cell type enhanced" "Detected in many" "B-cells: 22.2;Kupffer cells: 54.6;Macrophages: 40.8;monocytes: 45.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 139.0;intermediate monocyte: 63.8;myeloid DC: 139.3" "Group enriched" "Detected in many" 8 "dendritic cells: 139.3;monocytes: 139.0" "Cell line enhanced" "Detected in some" "HHSteC: 10.2;JURKAT: 49.4;MOLT-4: 13.6;THP-1: 8.8" "Low region specificity" "Detected in all" "CAB016107, HPA072662" Enhanced Supported "Endoplasmic reticulum" NA NA 880000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "CAB016107: AB_626960, HPA072662: AB_2686545" "unprognostic (8.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (3.85e-1)" "unprognostic (9.67e-3)" "unprognostic (2.37e-1)" "unprognostic (3.52e-1)" "unprognostic (2.23e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (9.31e-3)" "unprognostic (2.35e-1)" "unprognostic (2.32e-2)" "unprognostic (3.38e-1)" 2.7 2.0 0.1 7.5 0.2 3.1 2.0 0.1 0.4 1.5 0.7 4.4 7.4 2.2 0.5 0.8 2.1 1.8 3.3 0.1 0.2 2.2 15.3 3.4 4.7 0.3 0.2 0.6 1.9 0.3 1.0 0.4 0.3 2.2 2.9 0.3 1.1 0.7 1.1 0.3 18.2 2.3 0.1 23.9 2.3 2.5 0.2 9.4 2.7 0.6 3.0 1.8 1.0 0.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.0 0.0 3.5 0.0 6.0 0.0 0.0 0.1 0.2 0.0 0.0 10.2 0.1 0.0 3.9 0.6 0.0 0.7 0.0 0.0 49.4 0.0 0.0 0.0 0.0 13.6 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 8.8 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.3 0.0 3.7 0.4 0.2 139.0 0.4 0.2 63.8 0.5 17.6 0.1 0.1 139.3 13.4 0.1 0.0 7.2 0.3 11.0 1.4 0.2 80.7 0.1 0.2 0.1 0.4 0.1 0.2 0.3 0.2 0.3 0.1 0.2 0.4 9.4 0.0 3.6 0.0 22.2 0.3 0.5 0.8 0.6 0.7 0.1 0.9 0.7 2.8 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.4 5.6 0.4 2.0 2.4 2.4 1.7 0.0 0.0 0.2 0.5 0.0 0.3 1.3 0.1 3.3 6.3 11.3 1.7 0.2 2.0 0.0 54.6 0.8 2.1 0.0 40.8 0.0 0.0 45.4 0.6 1.0 0.0 0.0 0.0 6.4 0.0 3.7 0.1 7.3 0.1 0.0 0.3 0.0 1.2 0.4 1.0 2.1 0.0 0.1 0.1 0.6 0.1 4.5 0.1 CD22 "SIGLEC-2, SIGLEC2" ENSG00000012124 "CD22 molecule" P20273 19 35319261-35347361 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 141.3;lymphoid tissue: 230.2;ovary: 132.8" "Group enriched" "Detected in many" 7 "B-cells: 143.6;granulocytes: 95.8;Granulosa cells: 51.3;Oligodendrocytes: 91.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 24 "memory B-cell: 97.6;naive B-cell: 120.3" "Lineage enriched" "Detected in many" 26 "B-cells: 120.3" "Cell line enhanced" "Detected in some" "Daudi: 280.6;REH: 83.8;U-698: 219.9;WM-115: 50.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002418, HPA024353, HPA066523" Enhanced NA NA 13000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB002418: AB_563529, HPA024353: AB_10600695, HPA066523: " "unprognostic (2.80e-3)" "unprognostic (3.99e-2)" "unprognostic (6.79e-3)" "unprognostic (9.17e-2)" "unprognostic (3.07e-1)" "unprognostic (6.45e-3)" "unprognostic (3.79e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.47e-1)" "unprognostic (1.75e-3)" "unprognostic (1.98e-2)" "unprognostic (1.48e-2)" "unprognostic (9.05e-2)" "unprognostic (3.04e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" 2.7 5.5 39.2 75.3 66.8 13.6 1.7 42.8 58.4 2.7 17.8 4.9 2.3 3.7 2.5 2.2 30.9 4.1 1.3 42.7 53.2 2.1 1.5 7.4 219.2 63.3 53.8 132.8 0.6 0.7 2.1 1.8 60.3 2.9 6.4 0.0 3.5 1.1 0.2 0.3 53.4 2.1 37.8 161.6 7.0 3.8 55.8 11.4 6.3 0.4 230.2 5.7 1.6 141.3 0.9 1.6 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.1 0.4 0.0 5.1 280.6 5.6 0.3 15.0 0.5 0.0 0.0 0.1 1.5 0.0 0.0 0.2 2.2 0.1 0.3 12.4 0.0 0.0 0.2 4.1 0.1 0.0 0.0 1.5 0.1 2.6 0.5 0.1 0.0 0.1 0.4 0.4 83.8 0.3 0.2 0.0 0.0 0.0 0.0 0.3 1.4 6.6 0.2 0.5 0.1 0.3 2.6 1.5 0.0 0.0 0.0 0.1 219.9 2.2 0.9 50.1 0.1 0.1 0.1 0.0 1.1 0.0 97.6 0.0 0.0 4.6 120.3 0.0 0.0 1.0 0.2 0.7 3.8 0.0 4.9 39.2 66.8 42.8 58.4 42.7 53.2 63.3 53.8 60.3 37.8 55.8 141.3 1.7 3.2 3.0 0.0 143.6 0.3 0.4 0.0 0.0 0.0 1.0 3.3 0.7 0.0 0.6 0.0 0.0 0.2 4.1 0.1 0.0 0.0 0.6 0.2 0.4 2.1 0.0 2.7 0.3 0.2 1.3 2.8 0.5 0.5 95.8 51.3 3.3 0.2 6.8 0.0 0.3 0.0 0.0 5.6 2.0 0.2 3.7 6.9 1.8 0.0 0.9 0.0 1.0 0.0 91.5 0.2 0.1 0.7 2.3 0.4 0.0 0.2 0.1 0.0 0.0 0.2 0.8 0.4 1.1 0.0 0.4 0.1 4.1 12.2 0.0 0.1 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD52 "CDW52, EDDM5, HE5" ENSG00000169442 "CD52 molecule" P31358 1 26317958-26320523 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "epididymis: 36173.0" "Cell type enhanced" "Detected in many" "B-cells: 1861.9;granulocytes: 568.6;Hofbauer cells: 562.6;Langerhans cells: 674.3;Macrophages: 690.5;monocytes: 814.2;NK-cells: 602.5;T-cells: 1300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Daudi: 708.6;REH: 1042.2;U-266/84: 1087.0;U-698: 1159.2" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "prognostic favorable (1.85e-5)" "unprognostic (3.28e-3)" "unprognostic (1.93e-2)" "prognostic favorable (2.06e-4)" "unprognostic (4.18e-2)" "prognostic favorable (4.45e-4)" "unprognostic (9.11e-2)" "unprognostic (2.98e-2)" "unprognostic (7.73e-3)" "unprognostic (6.27e-2)" "unprognostic (4.58e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.64e-1)" "unprognostic (6.14e-2)" "unprognostic (7.95e-2)" "unprognostic (1.26e-1)" 62.1 10.2 10.2 297.8 13.5 266.9 59.5 9.6 38.5 26.1 12.6 68.6 41.7 21.3 36173.0 35.0 18.4 89.2 18.0 10.3 10.0 18.7 55.0 449.2 1082.0 11.3 10.0 9.6 8.2 5.4 6.1 16.9 10.5 19.2 96.9 0.2 37.6 104.2 9.4 27.9 294.7 47.4 10.1 646.5 87.2 4.7 16.5 1051.6 24.9 13.8 1256.4 134.9 13.1 10.5 2.0 0.0 0.3 0.0 0.0 1.4 14.3 0.1 1.0 0.1 0.0 0.3 0.6 708.6 1.4 0.0 0.3 0.1 0.0 0.2 0.0 0.5 0.2 34.8 0.0 1.4 0.0 7.5 106.4 0.0 0.0 0.2 0.0 0.7 0.0 44.9 23.7 1.0 0.0 4.6 8.5 62.9 3.0 0.5 0.0 1042.2 0.9 16.6 0.0 0.0 2.1 9.3 0.4 1.1 1.3 9.2 0.3 12.5 1.6 0.0 2.7 0.7 1.2 2.9 1087.0 1159.2 0.1 17.8 0.1 599.3 4558.9 9769.3 6605.8 7389.3 5319.0 10570.4 8177.1 6530.7 3180.2 10064.7 5495.2 5664.3 334.5 3732.1 6667.9 1034.9 11684.0 22571.2 10.2 13.5 9.6 38.5 10.3 10.0 11.3 10.0 10.5 10.1 16.5 10.5 9.5 67.3 194.6 0.0 1861.9 45.4 0.8 0.2 3.4 0.0 8.4 5.8 6.2 14.3 50.1 49.7 0.0 4.7 415.9 1.9 0.0 1.3 0.8 3.9 2.6 29.5 0.0 60.6 0.3 0.2 5.8 18.1 29.6 7.1 568.6 0.0 17.5 3.6 562.6 0.0 0.1 2.3 0.0 262.6 674.3 1.4 0.0 690.5 106.7 1.9 814.2 0.0 602.5 0.0 0.1 0.2 2.8 0.0 133.7 3.1 0.7 11.5 17.5 0.0 0.0 7.3 9.1 0.3 0.5 3.2 31.4 5.6 1300.0 0.0 2.7 1.1 CD69 CLEC2C ENSG00000110848 "CD69 molecule" Q07108 12 9752486-9760901 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 169.1;lymphoid tissue: 94.4" "Cell type enhanced" "Detected in many" "B-cells: 1017.1;dendritic cells: 694.0;granulocytes: 1455.3;Plasma cells: 308.8;T-cells: 1185.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 26.7;T-cells: 30.8" "Cell line enhanced" "Detected in some" "HL-60: 30.0;JURKAT: 19.5;K-562: 58.4;MOLT-4: 20.9;U-266/70: 22.5;U-698: 25.6;U-937: 97.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002503, HPA050525" Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB002503: AB_563625, HPA050525: AB_2681157" "prognostic favorable (3.31e-5)" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "unprognostic (7.10e-3)" "unprognostic (4.76e-3)" "unprognostic (9.53e-3)" "unprognostic (9.73e-3)" "unprognostic (1.64e-2)" "unprognostic (1.96e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.88e-2)" "unprognostic (3.32e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" 14.0 6.2 0.9 48.1 0.7 169.1 18.9 1.2 1.0 9.3 2.2 8.9 8.2 6.0 2.9 11.9 7.7 27.3 3.5 0.7 1.7 4.9 12.9 22.6 94.4 1.7 1.1 2.6 1.7 2.0 4.0 2.6 1.6 10.4 21.3 0.2 5.1 2.9 0.7 4.3 19.5 14.3 2.2 43.6 11.8 1.3 1.0 57.0 6.9 4.6 60.1 18.0 7.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 1.1 0.0 1.5 0.0 0.0 0.0 0.0 12.1 0.0 0.0 1.5 30.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 19.5 58.4 0.0 0.0 0.0 20.9 5.9 0.0 0.0 0.0 0.1 0.0 0.0 0.9 8.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 22.5 2.7 25.6 0.0 97.8 0.0 1.3 0.1 5.9 22.9 0.1 30.8 6.0 14.5 16.9 0.1 6.2 20.6 15.6 0.3 26.7 0.0 0.0 7.9 7.3 0.9 0.7 1.2 1.0 0.7 1.7 1.7 1.1 1.6 2.2 1.0 2.4 13.5 41.7 116.7 0.0 1017.1 18.5 3.8 0.0 10.8 0.1 11.8 14.7 2.0 7.2 5.0 1.8 0.0 0.9 694.0 1.1 0.0 1.1 0.4 5.7 3.6 14.3 0.0 33.7 0.0 0.0 0.3 15.4 63.7 16.7 1455.3 0.0 14.6 2.4 16.6 0.0 0.0 0.2 0.0 15.4 77.1 0.3 0.0 80.1 33.8 10.3 3.2 0.1 57.7 0.0 0.1 0.0 0.1 0.0 308.8 2.2 0.4 2.1 1.5 0.6 0.0 4.3 9.2 0.1 0.3 4.2 18.2 1.9 1185.9 0.0 0.9 3.3 CD72 "CD72b, LYB2" ENSG00000137101 "CD72 molecule" P21854 9 35609979-35646810 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 65.0" "Cell type enhanced" "Detected in many" "B-cells: 95.6;dendritic cells: 18.3;Hofbauer cells: 18.7;Kupffer cells: 25.6;Macrophages: 21.1;NK-cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 232.9;naive B-cell: 413.5" "Lineage enriched" "Detected in all" 20 "B-cells: 413.5" "Cell line enhanced" "Detected in some" "Daudi: 21.4;Karpas-707: 14.5;REH: 7.8;U-698: 44.4" "Region enriched" "Detected in single" 7 "basal ganglia: 4.1" "Low region specificity" "Detected in single" "CAB002505, HPA044658" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Mitochondria" "CAB002505: AB_563629, HPA044658: AB_2679039" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.21e-2)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (7.81e-2)" "unprognostic (7.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.29e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (2.49e-8)" "unprognostic (1.42e-1)" "unprognostic (2.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.59e-2)" 4.5 2.3 1.9 20.6 2.0 6.7 1.7 2.0 3.3 1.4 4.2 1.9 1.3 1.0 4.8 0.6 1.2 4.1 0.7 1.8 1.8 2.2 6.0 2.8 65.0 2.8 1.8 0.8 2.2 1.1 2.5 3.3 2.4 1.5 1.3 0.4 1.6 0.7 0.6 2.0 8.4 1.6 1.9 53.6 2.6 0.8 3.3 6.9 2.4 0.0 50.2 4.2 0.9 2.3 0.1 0.0 0.6 0.5 0.9 5.2 0.1 0.3 0.1 0.4 0.7 0.0 0.2 21.4 0.1 0.3 0.1 0.0 0.0 0.1 0.5 1.8 0.4 0.6 0.2 0.0 0.5 0.3 4.1 1.5 0.0 0.2 0.4 0.9 0.0 4.9 0.0 14.5 1.1 0.0 0.3 2.7 0.2 0.0 0.1 7.8 0.0 5.5 0.0 0.0 0.3 0.5 0.0 0.1 0.1 0.3 0.2 0.2 0.1 0.7 0.2 0.2 0.0 0.3 0.3 44.4 0.8 0.5 0.0 0.6 2.0 0.3 3.1 3.5 4.3 232.9 1.5 2.2 20.2 413.5 0.7 2.4 1.4 10.6 0.5 11.0 1.7 14.8 1.9 2.0 2.0 3.3 1.8 1.8 2.8 1.8 2.4 1.9 3.3 2.3 0.7 0.0 0.6 5.9 95.6 1.0 0.5 0.9 0.6 0.0 1.3 1.3 1.1 1.5 0.4 3.7 0.0 0.2 18.3 0.7 0.0 0.8 0.2 0.4 0.6 0.9 1.8 2.7 1.0 0.7 0.3 0.9 1.1 0.4 0.0 0.8 0.7 0.2 18.7 0.0 1.2 0.2 0.0 25.6 14.6 0.3 0.9 21.1 0.0 0.0 3.0 0.6 19.6 2.0 4.4 1.1 0.0 0.4 2.7 0.5 0.6 0.7 1.3 0.7 0.0 0.5 0.9 1.1 1.7 0.2 1.1 0.3 5.9 0.5 0.4 0.4 CD79A "IGA, MB-1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 152.3;lymphoid tissue: 545.2" "Group enriched" "Detected in some" 5 "B-cells: 1186.4;Plasma cells: 956.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "memory B-cell: 1273.8;naive B-cell: 1457.5" "Lineage enriched" "Detected in all" 40 "B-cells: 1457.5" "Group enriched" "Detected in some" 22 "Daudi: 1598.7;REH: 491.0;U-698: 1366.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000019, HPA056444" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB000019: AB_2244527, HPA056444: " "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" 4.8 4.9 0.2 213.4 0.2 47.2 9.5 0.2 0.4 3.6 0.1 47.3 37.9 2.4 1.4 9.9 1.8 13.0 2.9 0.1 0.1 3.4 2.6 8.9 482.4 0.3 0.2 3.7 0.6 0.1 0.3 1.2 0.2 4.3 28.9 0.0 28.5 2.2 0.7 0.4 152.3 2.2 0.6 286.5 76.9 2.4 0.2 93.7 8.1 0.4 545.2 32.3 1.9 0.3 1.1 0.8 0.3 0.1 0.2 0.7 0.2 0.2 0.0 0.3 0.0 0.0 0.1 1598.7 1.2 0.0 0.1 0.0 0.2 0.2 0.0 0.5 0.7 2.7 0.0 1.7 0.2 2.6 1.8 0.5 0.6 0.2 0.0 0.0 0.0 8.0 3.1 0.4 0.1 1.1 1.6 9.9 0.1 0.1 0.4 491.0 0.8 2.5 0.1 0.0 0.5 0.5 0.8 0.5 1.3 0.0 0.0 4.8 1.6 0.1 4.3 0.3 0.8 7.8 1.4 1366.7 0.0 52.1 0.1 12.4 1.5 6.9 1.7 1.8 0.7 1273.8 4.1 2.1 2.5 1457.5 4.9 26.3 4.6 2.6 4.3 36.3 10.4 62.7 0.2 0.2 0.2 0.4 0.1 0.1 0.3 0.2 0.2 0.6 0.2 0.3 0.2 0.0 2.4 0.0 1186.4 1.8 0.5 0.5 0.6 0.0 0.7 0.9 0.2 1.5 0.2 0.0 0.0 0.2 18.2 0.7 0.0 1.8 0.2 0.1 0.3 0.5 0.0 10.5 0.0 25.6 0.4 2.2 6.6 0.2 0.0 0.4 2.2 1.0 0.8 0.0 0.0 0.4 0.0 4.1 1.4 0.0 0.3 5.3 138.7 0.0 6.3 0.0 15.5 0.0 0.0 181.7 0.4 0.4 956.7 0.3 0.2 0.9 0.0 0.0 0.0 0.2 0.7 0.3 0.6 0.9 1.4 0.1 23.5 0.2 5.3 0.2 CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 266.7" "Cell type enriched" "Detected in many" 4 "B-cells: 491.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "memory B-cell: 1132.1;naive B-cell: 1505.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1505.8" "Cell line enhanced" "Detected in some" "Daudi: 1060.0;REH: 350.2;U-698: 1475.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" 5.0 1.7 0.9 70.5 0.9 54.6 3.4 0.9 1.4 1.9 1.7 7.7 4.7 1.4 1.6 2.6 1.5 6.8 12.3 0.9 0.9 4.7 3.4 4.9 266.7 1.0 0.9 0.6 0.7 0.7 25.3 3.8 0.9 2.5 7.2 0.0 7.8 0.8 3.4 2.4 66.2 2.6 0.9 147.7 10.7 1.0 1.0 27.1 4.1 5.8 208.4 13.4 2.2 1.0 1.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.4 0.0 0.0 1060.0 7.8 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.4 0.6 0.6 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.4 1.2 56.9 0.0 0.0 0.6 23.0 0.3 0.0 0.0 350.2 0.9 4.4 0.0 0.0 0.5 0.0 1.7 0.0 0.7 5.8 0.0 16.2 1.7 0.1 3.7 0.3 0.6 51.3 54.4 1475.5 0.0 2.2 0.0 6.2 13.0 1.1 44.9 192.2 51.3 1132.1 57.1 30.1 47.0 1505.8 38.4 23.2 5.8 42.4 304.3 6.7 107.9 112.1 0.9 0.9 0.9 1.4 0.9 0.9 1.0 0.9 0.9 0.9 1.0 1.0 24.9 0.0 1.3 0.0 491.9 4.5 0.4 0.0 1.8 0.0 1.1 4.4 1.4 1.5 0.0 0.0 0.0 0.2 24.2 0.3 0.0 0.1 0.6 0.3 1.0 25.2 1.2 8.6 0.0 0.0 0.4 3.3 0.5 0.3 15.2 0.0 51.4 1.3 5.8 0.0 0.0 0.4 0.0 14.8 5.1 1.4 1.2 13.4 21.4 0.0 14.3 0.0 36.0 0.0 0.0 0.0 0.1 1.9 99.6 0.4 0.0 1.0 0.0 0.0 0.0 4.4 5.4 1.2 0.3 0.7 3.1 0.4 27.0 0.5 0.8 0.2 CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 51.0;Spermatogonia: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.0;naive B-cell: 124.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 10.1" "HPA027169, HPA074623" Approved Supported Nucleoplasm,Nucleoli,Cytosol No Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA027169: AB_1856058, HPA074623: " "unprognostic (5.13e-3)" "unprognostic (5.94e-2)" "unprognostic (1.91e-1)" "unprognostic (4.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.36e-6)" "unprognostic (4.09e-2)" "unprognostic (2.86e-1)" "unprognostic (3.87e-2)" "unprognostic (3.22e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-3)" 5.9 1.4 3.9 15.0 9.1 51.7 15.7 5.7 5.2 8.7 17.8 17.0 10.7 13.8 5.5 11.2 11.5 8.1 25.3 3.9 3.5 2.8 4.8 14.0 37.1 6.9 4.8 21.8 13.0 1.8 1.1 4.7 3.8 7.3 19.0 5.1 9.0 7.6 6.2 18.5 13.6 11.9 5.0 13.3 17.8 18.5 7.8 49.0 29.8 3.4 31.8 6.3 8.1 9.8 84.5 27.6 26.0 0.6 14.5 17.9 0.0 65.9 58.2 51.8 73.5 11.3 75.4 173.6 21.8 59.3 102.4 51.1 41.4 69.4 103.6 0.3 28.6 42.3 83.8 7.4 21.1 111.1 0.4 35.2 12.7 40.0 116.9 54.9 104.8 133.5 58.3 0.1 41.4 34.5 146.1 46.1 153.2 17.4 36.2 141.0 94.0 119.8 15.4 14.8 96.9 79.7 30.3 19.9 29.9 34.4 45.6 54.6 43.0 57.1 68.5 101.3 83.8 90.6 63.6 223.0 55.7 154.6 54.5 1.1 2.3 43.2 2.2 3.8 0.3 101.0 6.4 3.2 14.9 124.5 30.9 12.8 3.8 3.4 4.9 75.9 9.9 12.2 3.9 9.1 5.7 5.2 3.9 3.5 6.9 4.8 3.8 5.0 7.8 9.8 1.0 19.2 31.5 7.5 51.0 27.1 23.7 6.9 17.1 1.5 12.5 20.7 38.7 11.5 19.0 0.0 2.1 0.5 30.7 8.4 3.9 8.9 7.3 5.4 2.7 4.8 10.7 21.9 0.5 6.2 0.3 13.4 18.3 5.3 8.8 14.9 1.4 4.0 10.8 13.5 1.0 26.1 8.2 15.2 3.5 5.2 4.1 7.0 8.8 1.9 1.6 2.4 1.0 15.1 8.7 3.9 7.4 2.6 20.2 14.2 1.5 0.1 4.2 2.7 13.1 6.8 12.4 4.6 63.5 9.6 7.7 0.3 5.4 8.3 23.0 6.2 CEPT1 ENSG00000134255 "Choline/ethanolamine phosphotransferase 1" Q9Y6K0 1 111139627-111185104 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "unprognostic (1.16e-1)" "unprognostic (2.42e-1)" "unprognostic (1.47e-3)" "unprognostic (1.83e-2)" "prognostic favorable (4.96e-4)" "unprognostic (5.52e-2)" "unprognostic (1.10e-1)" "unprognostic (5.61e-2)" "unprognostic (1.54e-3)" "unprognostic (1.84e-1)" "unprognostic (9.20e-3)" "unprognostic (1.03e-1)" "unprognostic (4.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "unprognostic (5.88e-2)" "unprognostic (1.27e-2)" 20.7 17.9 14.9 20.2 15.1 5.4 12.0 15.7 19.5 11.0 15.4 12.0 17.0 12.5 15.9 13.2 14.0 13.3 6.7 14.3 16.5 19.9 36.2 13.3 31.7 15.8 14.8 19.2 10.6 18.7 6.1 17.0 15.8 10.8 15.4 8.1 17.5 9.5 9.2 15.1 18.3 12.7 16.5 27.6 14.6 8.9 15.2 20.2 16.8 10.8 22.9 16.8 9.9 18.4 27.3 10.0 11.6 11.3 44.8 22.0 28.1 29.5 16.5 13.4 16.0 8.7 30.0 32.1 31.7 15.2 17.0 32.6 16.7 22.9 18.9 24.1 26.4 14.0 16.3 19.6 29.9 33.4 19.3 18.1 42.8 9.8 46.1 25.4 18.0 32.8 30.9 20.5 17.6 19.8 34.6 32.9 18.0 43.2 20.3 18.4 36.8 26.3 22.0 17.0 15.2 8.2 27.1 40.2 33.2 22.4 21.8 35.5 15.8 21.7 13.6 47.4 20.0 18.5 21.6 24.9 29.2 29.6 42.0 4.4 10.0 5.8 7.9 18.3 10.3 17.9 8.7 8.2 12.1 17.8 10.0 11.0 2.5 8.7 27.5 9.3 8.3 7.4 14.9 15.1 15.7 19.5 14.3 16.5 15.8 14.8 15.8 16.5 15.2 18.4 11.5 35.3 14.9 20.9 45.5 13.0 16.5 30.8 13.6 25.1 11.1 6.2 3.6 17.2 26.9 36.8 35.5 30.1 16.7 20.7 5.9 13.4 1.9 15.8 16.9 12.3 10.2 21.4 42.4 8.1 19.7 15.2 12.2 11.1 19.0 15.2 19.6 37.8 28.3 28.6 49.2 15.0 20.3 52.1 13.9 3.7 14.6 26.0 16.0 42.2 24.7 10.0 34.0 47.3 59.5 8.5 19.9 17.0 18.5 16.0 26.1 15.2 29.2 29.3 13.1 9.9 10.1 17.1 14.7 13.0 15.3 19.0 17.2 19.1 14.4 15.4 CHI3L2 "YKL-39, YKL39" ENSG00000064886 "Chitinase 3 like 2" Q15782 1 111200771-111243440 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 200.6;salivary gland: 142.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 118.1;B-cells: 76.4;Breast glandular cells: 32.2;Breast myoepithelial cells: 30.4;Leydig cells: 74.9" "Cancer enriched" "Detected in many" 8 "glioma: 104.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 91.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "JURKAT: 634.6;MOLT-4: 346.8" "Low region specificity" "Detected in all" HPA005443 Approved "Secreted to blood" NA NA 420000 "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA005443: AB_1078510" "unprognostic (1.02e-2)" "unprognostic (4.34e-2)" "unprognostic (1.37e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (9.10e-5)" "prognostic favorable (2.19e-4)" "unprognostic (7.12e-2)" "unprognostic (1.39e-1)" "unprognostic (1.49e-3)" "unprognostic (1.26e-2)" "unprognostic (1.32e-2)" "unprognostic (2.44e-2)" "prognostic unfavorable (8.59e-7)" "unprognostic (7.15e-3)" "unprognostic (7.68e-2)" "unprognostic (1.39e-3)" "unprognostic (1.20e-1)" 22.1 3.0 12.4 112.7 12.0 2.4 44.6 9.2 41.6 1.0 10.9 3.2 1.2 1.7 0.2 5.1 2.2 11.8 23.0 12.3 13.6 3.1 0.9 66.1 59.8 63.7 34.7 2.1 0.8 36.6 4.5 13.7 27.1 7.4 2.6 1.7 142.1 0.7 2.0 11.3 10.0 3.7 18.6 21.5 5.9 11.7 34.5 200.6 11.8 7.5 119.0 53.5 4.5 26.4 0.3 0.0 0.4 0.5 100.3 19.1 0.2 0.1 1.3 0.2 0.2 0.0 0.3 0.8 0.2 0.1 8.8 0.6 3.5 0.2 0.1 29.0 0.1 0.2 0.5 1.6 1.5 0.2 1.7 27.9 0.3 0.4 0.5 5.5 0.0 634.6 0.2 1.2 0.3 0.2 346.8 0.5 0.0 0.1 0.1 1.8 0.9 0.6 0.0 0.7 0.1 0.3 0.4 0.9 0.3 2.1 0.3 0.3 0.5 7.5 1.4 0.2 0.7 5.2 0.6 76.8 23.4 0.5 2.3 1.0 3.6 0.2 22.4 0.8 5.5 45.0 16.0 37.5 0.8 43.2 91.6 34.4 2.2 17.2 0.3 1.4 10.8 27.3 12.4 12.0 9.2 41.6 12.3 13.6 63.7 34.7 27.1 18.6 34.5 26.4 0.5 9.6 118.1 1.0 76.4 2.3 1.6 8.3 0.0 0.1 32.2 30.4 0.5 0.0 3.1 0.0 0.0 0.2 7.8 0.1 0.0 20.1 3.8 0.3 7.0 0.9 1.2 0.0 0.2 0.4 0.9 10.8 0.0 0.7 2.5 0.0 0.4 0.0 1.1 0.0 0.1 0.0 0.0 2.2 0.7 12.0 74.9 2.2 16.0 0.0 0.8 0.0 23.7 0.0 0.3 0.9 0.0 1.5 2.6 3.5 0.0 0.5 0.2 0.0 0.0 1.8 0.7 0.5 0.6 0.3 1.3 3.1 12.8 1.5 0.0 1.3 CHMP7 MGC29816 ENSG00000147457 "Charged multivesicular body protein 7" Q8WUX9 8 23243637-23262000 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 10 "B-cells: 35.7;T-cells: 76.3" "Cell line enhanced" "Detected in all" "Daudi: 39.7;U-698: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036119 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA036119: AB_10673000" "unprognostic (2.94e-3)" "unprognostic (1.64e-1)" "unprognostic (7.59e-3)" "unprognostic (4.51e-2)" "unprognostic (2.47e-1)" "unprognostic (2.83e-3)" "unprognostic (9.00e-2)" "unprognostic (1.84e-1)" "unprognostic (6.44e-2)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (8.98e-3)" "unprognostic (1.88e-2)" "unprognostic (6.80e-3)" "unprognostic (2.06e-1)" "unprognostic (7.54e-2)" "unprognostic (2.30e-1)" 4.6 5.9 2.3 19.5 2.4 9.8 4.5 3.6 3.2 5.1 1.4 6.0 4.0 6.2 1.4 4.8 4.9 3.4 3.9 2.3 2.9 3.4 3.5 4.7 32.8 3.4 2.0 4.4 2.7 2.7 3.6 2.1 3.5 4.1 3.4 2.2 5.2 3.6 7.0 4.6 14.7 2.6 1.9 16.9 5.8 4.8 2.9 31.0 4.4 3.9 27.7 5.6 4.7 4.8 6.2 8.6 4.6 7.8 4.2 4.0 5.2 5.0 3.6 7.2 6.1 9.6 4.8 39.7 6.0 3.7 6.9 5.9 4.3 6.3 2.9 10.6 7.4 8.4 11.5 4.9 3.6 2.4 11.4 3.4 4.2 7.0 1.9 4.1 6.0 16.7 9.3 5.6 4.2 6.0 7.3 9.3 7.1 5.9 6.5 2.8 3.7 5.5 3.7 8.0 5.6 5.5 3.9 5.9 2.3 2.5 6.2 4.5 6.7 8.9 5.7 6.7 4.0 15.1 8.5 47.2 6.6 6.6 6.6 1.2 4.8 5.0 6.3 4.8 12.7 35.7 41.3 19.0 3.7 35.6 76.3 45.2 4.3 5.4 3.5 3.0 46.8 32.7 2.3 2.4 3.6 3.2 2.3 2.9 3.4 2.0 3.5 1.9 2.9 4.8 8.6 6.4 7.9 7.2 48.6 13.6 15.8 12.1 12.5 11.9 11.3 10.9 13.2 11.5 11.8 14.7 4.2 15.8 12.7 16.9 19.6 19.7 43.5 5.5 11.3 12.1 13.8 8.6 9.3 15.8 18.8 11.1 11.7 10.2 12.0 13.1 6.4 7.0 15.9 13.5 11.4 13.1 14.2 7.5 7.7 13.7 9.9 13.1 16.0 1.9 17.3 20.6 21.6 3.5 9.5 20.5 12.4 10.5 24.0 15.9 16.0 18.8 7.1 10.6 6.6 10.1 13.1 15.7 16.8 9.2 10.7 20.7 25.7 10.1 10.8 19.6 CLEC17A FLJ45910 ENSG00000187912 "C-type lectin domain containing 17A" Q6ZS10 19 14583084-14612035 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 6.6;lymphoid tissue: 18.2" "Group enriched" "Detected in some" 4 "B-cells: 20.7;Early spermatids: 5.3;Late spermatids: 12.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 11 "memory B-cell: 21.5;naive B-cell: 43.1" "Lineage enriched" "Detected in many" 14 "B-cells: 43.1" "Group enriched" "Detected in some" 5 "Daudi: 5.7;U-698: 9.9" "Not detected" "Not detected" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.71e-5)" "unprognostic (1.34e-2)" "unprognostic (9.64e-4)" "unprognostic (5.02e-3)" "unprognostic (3.90e-1)" "unprognostic (9.00e-4)" "unprognostic (3.18e-3)" "unprognostic (1.60e-3)" "unprognostic (1.32e-2)" "unprognostic (7.11e-2)" "unprognostic (3.78e-2)" "unprognostic (4.43e-2)" "unprognostic (9.13e-3)" "unprognostic (1.65e-1)" "unprognostic (5.91e-2)" "unprognostic (2.07e-1)" "unprognostic (1.23e-1)" 0.3 0.2 0.7 8.2 0.7 2.2 0.1 1.6 0.9 0.0 0.9 0.5 0.5 0.3 0.2 0.2 0.2 0.6 0.2 0.7 0.9 0.2 0.2 0.2 16.1 1.3 0.9 0.2 0.0 0.1 0.1 0.2 1.2 0.3 0.6 0.4 0.6 0.1 0.3 0.5 6.6 0.1 0.9 11.4 0.7 0.9 0.8 1.4 0.2 0.1 18.2 0.9 0.0 1.5 0.1 0.0 0.1 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.3 0.1 0.1 0.4 0.1 0.0 0.2 1.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.4 0.0 0.2 0.1 1.4 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.3 0.1 9.9 0.3 0.1 0.1 0.7 0.7 0.3 0.2 0.4 0.2 21.5 0.1 0.1 3.0 43.1 0.2 0.2 2.7 0.4 0.3 0.5 0.1 2.2 0.7 0.7 1.6 0.9 0.7 0.9 1.3 0.9 1.2 0.9 0.8 1.5 0.0 0.0 0.0 1.3 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 12.7 0.0 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLECL1 DCAL1 ENSG00000184293 "C-type lectin like 1" Q8IZS7 12 9715860-9733299 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 9.9;lymphoid tissue: 31.1" "Group enriched" "Detected in some" 4 "B-cells: 87.0;dendritic cells: 24.0;Hofbauer cells: 22.2;Kupffer cells: 82.3;Langerhans cells: 64.6;Macrophages: 23.9;monocytes: 55.9;Plasma cells: 42.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 120.9" "Lineage enriched" "Detected in many" 5 "B-cells: 120.9" "Group enriched" "Detected in some" 5 "HEL: 49.7;Karpas-707: 66.2;U-698: 173.0;U-937: 95.6" "Low region specificity" "Detected in many" HPA063928 Supported "Plasma membrane,Centriolar satellite" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Centriolar satellite" "HPA063928: " "unprognostic (2.18e-2)" "unprognostic (2.35e-3)" "unprognostic (2.20e-3)" "unprognostic (1.90e-3)" "unprognostic (3.66e-1)" "unprognostic (1.90e-3)" "unprognostic (2.83e-1)" "unprognostic (7.55e-4)" "unprognostic (5.10e-2)" "unprognostic (2.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-5)" "unprognostic (3.31e-1)" "unprognostic (2.45e-1)" "unprognostic (6.10e-2)" "unprognostic (7.39e-2)" 1.0 1.6 0.6 9.9 0.9 1.9 2.0 1.4 0.9 0.9 1.3 3.0 2.7 0.9 0.0 0.7 0.8 2.5 0.4 0.6 0.9 0.7 2.1 2.1 24.8 1.8 1.1 0.5 0.2 0.3 0.3 0.7 1.4 0.7 4.3 0.1 1.3 0.5 0.1 0.4 9.9 1.8 1.2 16.2 4.5 0.9 1.1 5.2 0.6 0.2 31.1 3.0 0.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.7 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.2 0.0 0.1 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.1 0.2 1.2 173.0 0.0 95.6 0.0 2.4 7.9 0.4 4.5 14.4 0.1 120.9 3.9 9.7 18.7 54.3 0.2 1.4 0.3 0.3 15.5 25.4 0.2 5.2 0.6 0.9 1.4 0.9 0.6 0.9 1.8 1.1 1.4 1.2 1.1 1.6 0.3 0.0 0.0 0.0 87.0 2.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.0 1.8 0.0 0.0 0.1 24.0 0.1 0.0 0.0 1.0 0.1 0.1 0.3 0.0 4.4 0.0 0.2 0.1 0.6 0.0 0.1 5.1 0.0 0.4 0.4 22.2 0.0 0.0 0.2 0.0 82.3 64.6 1.4 0.3 23.9 12.4 1.0 55.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.4 0.0 0.0 6.6 0.1 0.1 0.0 0.2 0.1 1.8 0.3 11.2 0.0 0.0 0.1 CNPY3 "CAG4A, TNRC5" ENSG00000137161 "Canopy FGF signaling regulator 3" Q9BT09 6 42929192-42939294 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" Chaperone "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 248.5;Kupffer cells: 233.3;monocytes: 207.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016560 Uncertain "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 57: B-cells - Immune response" "HPA016560: AB_1858173" "unprognostic (5.26e-3)" "unprognostic (6.63e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (8.15e-2)" "unprognostic (3.12e-1)" "unprognostic (1.79e-1)" "unprognostic (5.70e-3)" "unprognostic (5.11e-2)" "unprognostic (4.77e-2)" "unprognostic (1.94e-2)" "unprognostic (2.26e-3)" "unprognostic (4.54e-2)" "prognostic unfavorable (9.85e-6)" "unprognostic (2.34e-1)" "unprognostic (1.93e-2)" "unprognostic (2.21e-2)" "unprognostic (2.98e-3)" 35.3 31.4 58.2 64.3 59.1 144.6 32.7 59.0 72.8 40.0 70.0 30.9 30.9 37.5 32.3 23.4 49.8 37.8 28.8 59.7 64.2 31.8 64.7 45.4 78.6 70.0 63.1 48.5 90.0 29.0 41.7 47.6 67.0 45.1 29.7 23.9 32.5 33.8 10.9 22.2 50.1 42.0 62.8 105.2 36.7 46.7 65.8 115.8 34.1 16.7 69.2 43.3 30.0 75.8 78.2 75.6 72.8 157.0 118.4 44.8 73.5 60.3 78.9 79.1 91.0 85.2 57.0 82.1 91.0 102.9 170.8 63.7 54.7 68.7 48.2 82.7 61.6 88.6 65.2 134.0 70.0 155.7 173.3 54.3 41.7 61.2 67.4 113.9 72.4 77.6 73.3 157.3 51.9 147.9 141.4 188.8 59.1 367.3 42.1 97.2 50.6 123.2 79.6 58.6 78.5 68.9 37.7 38.6 134.4 93.4 49.8 334.6 54.6 82.7 82.9 30.9 66.0 107.0 78.9 115.0 34.2 178.6 70.9 212.7 483.3 249.0 115.2 336.3 110.9 267.3 101.1 126.1 407.0 258.7 112.6 115.1 852.8 132.3 327.2 696.4 102.2 404.5 58.2 59.1 59.0 72.8 59.7 64.2 70.0 63.1 67.0 62.8 65.8 75.8 32.3 12.8 11.1 4.2 132.1 22.8 32.1 41.1 31.9 41.6 25.6 29.7 16.9 22.8 26.2 23.9 14.6 51.1 176.5 16.7 7.9 47.4 61.0 25.9 24.2 36.7 55.3 47.9 5.1 34.1 180.8 33.9 20.9 31.8 46.3 81.5 42.1 58.9 248.5 1.7 6.7 31.1 34.6 233.3 61.7 81.7 33.5 184.3 30.2 18.7 207.0 20.8 62.8 4.5 6.6 27.9 34.9 30.1 70.7 50.8 38.4 18.1 32.8 11.1 19.7 12.6 28.0 72.3 39.9 23.9 17.0 36.1 64.1 39.8 36.5 37.9 CNR2 CB2 ENSG00000188822 "Cannabinoid receptor 2" P34972 1 23870515-23913362 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.4;lymphoid tissue: 8.8" "Cell type enriched" "Detected in some" 5 "B-cells: 27.8" "Cancer enriched" "Detected in single" 6 "testis cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "basophil: 49.3;eosinophil: 35.1;memory B-cell: 29.6;naive B-cell: 27.9;NK-cell: 19.4" "Group enriched" "Detected in many" 9 "B-cells: 29.6;granulocytes: 49.3;NK-cells: 19.4" "Cell line enhanced" "Detected in some" "Daudi: 5.3;HEL: 4.4;HMC-1: 19.7;U-698: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" CAB009719 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB009719: AB_2082784" "unprognostic (9.45e-4)" "unprognostic (5.40e-3)" "unprognostic (8.50e-3)" "unprognostic (8.19e-3)" "unprognostic (3.55e-3)" "unprognostic (9.34e-6)" "unprognostic (5.58e-3)" "unprognostic (6.96e-3)" "unprognostic (1.74e-1)" "unprognostic (7.87e-2)" "unprognostic (1.53e-1)" "unprognostic (4.93e-2)" "unprognostic (1.04e-3)" "unprognostic (3.67e-1)" "unprognostic (1.80e-1)" "unprognostic (3.75e-2)" "unprognostic (4.91e-2)" 0.1 0.0 0.2 2.4 0.1 1.5 0.0 0.5 0.2 0.0 0.2 0.3 0.2 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 7.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.0 1.6 0.2 3.4 0.1 0.0 8.8 0.4 0.1 0.2 1.0 0.2 0.0 7.5 0.4 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.4 0.2 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 13.4 0.0 0.1 0.0 49.3 0.1 35.1 3.2 0.1 3.8 29.6 0.1 3.0 0.4 27.9 0.2 1.8 1.2 19.4 0.2 1.7 0.2 2.0 0.2 0.1 0.5 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.1 3.2 3.9 0.3 27.8 0.6 0.8 0.0 0.0 0.8 0.2 0.0 0.3 0.0 1.8 0.0 0.0 0.1 2.1 0.5 0.0 0.0 0.2 0.1 0.3 0.3 0.0 3.2 0.4 0.0 0.0 0.9 0.0 0.2 3.8 0.1 0.4 0.3 0.2 0.0 0.4 0.0 0.0 0.6 0.9 0.0 0.0 0.8 0.0 0.0 0.5 0.2 5.2 0.0 0.5 0.1 2.0 0.0 0.5 0.5 0.0 0.1 0.7 0.7 0.0 0.9 0.4 0.3 0.2 0.0 0.3 0.3 2.4 0.2 0.0 0.8 COBLL1 KIAA0977 ENSG00000082438 "Cordon-bleu WH2 repeat protein like 1" Q53SF7 2 164653624-164843679 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 218.8;Cone photoreceptor cells: 250.2;Microglial cells: 351.3;Syncytiotrophoblasts: 331.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 15.0;naive B-cell: 9.4;plasmacytoid DC: 8.1" "Group enriched" "Detected in many" 13 "B-cells: 15.0;dendritic cells: 8.1" "Cell line enhanced" "Detected in many" "Karpas-707: 62.6;RPTEC TERT1: 63.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044933, HPA053344" Enhanced Approved "Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Cell Junctions" "HPA044933: AB_2679148, HPA053344: AB_2682123" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.38e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-1)" "unprognostic (4.49e-3)" "unprognostic (1.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.27e-13)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "unprognostic (2.47e-1)" "unprognostic (1.42e-1)" 35.1 51.4 9.5 7.4 8.5 4.1 13.8 6.4 9.2 10.1 28.7 8.0 10.7 4.6 15.6 32.6 4.8 12.3 7.2 6.6 7.1 68.8 107.6 18.2 12.8 8.9 7.9 12.5 43.7 10.9 5.0 50.9 9.4 27.4 7.8 56.8 17.9 28.0 3.3 16.9 7.8 7.4 6.8 9.9 30.0 2.0 12.8 4.8 18.4 7.2 16.2 22.6 16.4 6.3 10.7 2.2 5.9 0.0 7.1 1.3 11.9 34.0 13.3 4.7 5.6 8.9 4.3 1.0 6.9 3.2 5.0 38.4 26.2 21.3 5.6 2.9 10.7 10.5 9.5 36.3 10.2 0.0 0.0 1.8 19.8 1.0 27.6 5.8 21.1 1.3 0.0 62.6 7.5 12.5 0.3 0.1 2.9 25.9 12.8 1.3 22.4 10.4 63.1 36.0 14.4 5.8 16.1 14.7 4.6 11.4 10.7 0.0 9.5 11.3 9.7 3.8 8.3 24.3 10.0 3.6 4.7 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.8 0.0 8.1 0.0 0.4 9.5 8.5 6.4 9.2 6.6 7.1 8.9 7.9 9.4 6.8 12.8 6.3 56.4 70.5 66.5 7.5 102.5 97.3 54.3 14.5 30.7 21.6 22.4 22.4 9.3 30.0 26.0 218.8 250.2 52.1 40.8 11.3 62.6 25.5 0.1 24.6 12.2 47.1 22.2 22.5 23.7 33.8 71.3 35.0 53.5 19.5 34.1 9.0 6.1 127.9 8.7 3.3 30.9 11.0 24.4 3.9 9.0 1.3 14.6 3.7 19.6 351.3 0.7 144.5 0.0 5.0 1.6 29.8 4.9 7.9 154.8 46.0 12.6 28.6 12.4 190.2 46.0 8.6 71.2 0.6 2.7 69.0 70.3 331.4 8.3 8.0 10.0 75.6 CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.2;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in some" "B-cells: 32.6;Erythroid cells: 20.4;Kupffer cells: 59.1;Macrophages: 24.9;monocytes: 13.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 53.7;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.7" "Group enriched" "Detected in some" 9 "HL-60: 9.9;HMC-1: 21.8;NB-4: 9.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" 13.2 0.8 0.1 27.2 0.5 10.5 0.6 0.1 2.9 1.2 1.3 1.5 1.3 0.5 0.2 0.9 1.4 2.1 0.6 0.2 0.2 2.5 2.6 3.2 20.1 0.7 0.5 0.2 0.3 0.1 0.2 9.1 1.6 0.2 1.5 0.0 0.4 0.4 0.2 0.1 4.4 6.3 0.1 24.4 1.7 0.6 2.1 1.6 0.3 1.0 17.9 6.7 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 9.9 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.7 4.2 17.2 0.0 2.4 0.7 4.5 0.9 0.4 0.3 2.2 0.2 0.1 15.6 0.0 2.3 0.0 0.0 1.3 0.1 0.5 0.1 2.9 0.2 0.2 0.7 0.5 1.6 0.1 2.1 1.8 0.3 0.0 4.2 0.3 32.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.2 0.2 0.0 20.4 0.3 0.0 0.1 0.6 0.0 0.2 1.3 0.3 0.0 0.4 9.7 0.0 0.4 0.0 0.0 59.1 1.4 0.0 0.0 24.9 0.0 1.9 13.3 0.0 0.0 1.5 4.4 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.3 0.5 0.0 0.0 CR2 "C3DR, CD21" ENSG00000117322 "Complement C3d receptor 2" P20023 1 207454230-207489895 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 174.0" "Group enriched" "Detected in some" 17 "B-cells: 54.9;Plasma cells: 14.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.1;stomach cancer: 5.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "memory B-cell: 17.5;naive B-cell: 20.3" "Lineage enriched" "Detected in many" 8 "B-cells: 20.3" "Cell line enhanced" "Detected in some" "Daudi: 24.0;JURKAT: 4.0;MOLT-4: 13.4;RPMI-8226: 4.7" "Not detected" "Not detected" "CAB002659, HPA052942, HPA060715" Enhanced NA NA 220000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB002659: , HPA052942: AB_2681994, HPA060715: AB_2684349" "prognostic favorable (6.90e-4)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (3.64e-2)" "unprognostic (2.65e-1)" "unprognostic (1.27e-3)" "unprognostic (1.18e-1)" "unprognostic (6.62e-3)" "unprognostic (1.91e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (7.95e-2)" "unprognostic (2.14e-1)" "unprognostic (1.12e-1)" "unprognostic (2.19e-1)" "unprognostic (2.09e-2)" "unprognostic (3.35e-2)" 2.0 0.0 0.1 53.1 0.1 0.8 0.6 0.0 0.2 0.0 0.0 5.1 0.9 0.4 0.0 0.7 0.1 2.0 0.1 0.2 0.0 6.2 0.4 1.1 174.0 0.1 0.2 0.0 0.2 0.1 0.0 0.2 0.1 1.1 4.0 0.0 4.3 0.0 0.2 0.0 16.7 0.4 0.0 73.2 6.9 0.5 0.1 15.2 0.8 0.0 171.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.1 13.4 0.0 2.1 0.0 0.3 0.0 0.2 4.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 17.5 1.0 0.6 0.0 20.3 2.4 2.2 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 54.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.2 1.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 14.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 1.0 0.1 0.0 0.0 CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782057-74803198 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 169.3" "Cell type enhanced" "Detected in all" "B-cells: 130.9;dendritic cells: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Enhanced Vesicles,Cytosol No No 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favorable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favorable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.74e-4)" "prognostic favorable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" 21.4 19.9 23.4 89.1 26.2 50.6 19.4 26.5 26.7 26.8 18.2 33.6 36.7 22.4 8.0 98.5 20.0 22.9 29.3 22.5 23.9 21.3 48.8 32.0 169.3 31.0 29.8 19.0 17.2 15.8 21.1 17.6 31.6 24.8 19.5 6.9 31.6 14.1 14.8 36.7 59.9 18.7 29.1 127.9 30.0 19.2 28.2 68.5 19.5 15.8 106.3 33.0 32.8 28.4 62.2 85.6 41.2 68.1 38.5 29.2 35.3 40.7 38.8 75.7 53.6 78.9 56.0 275.7 52.6 37.0 70.2 62.9 87.2 82.1 21.2 134.7 107.8 233.8 29.5 80.2 53.3 123.6 285.1 41.7 39.6 54.0 48.1 37.9 58.1 127.5 68.7 93.1 45.7 104.6 89.7 72.7 51.2 55.7 60.6 98.0 35.4 201.9 34.9 135.6 68.1 47.2 52.8 109.5 72.3 26.2 75.5 179.5 50.7 91.1 47.8 72.5 71.7 49.6 108.7 283.8 47.1 232.5 63.1 88.7 68.0 176.1 74.3 146.8 63.4 95.6 63.6 73.9 76.6 113.6 48.3 57.0 130.8 58.6 169.8 44.3 106.2 79.5 23.4 26.2 26.5 26.7 22.5 23.9 31.0 29.8 31.6 29.1 28.2 28.4 21.3 3.2 9.2 8.5 130.9 9.3 8.2 7.6 13.1 16.6 16.7 17.1 11.5 12.8 9.3 9.2 6.2 7.5 99.1 40.6 1.9 9.3 15.8 10.0 15.1 15.3 9.5 29.2 5.3 14.0 13.7 11.3 27.0 15.3 26.6 19.0 12.5 34.3 50.7 28.6 10.0 23.2 6.1 91.2 44.9 3.3 9.0 85.1 8.8 23.4 86.9 6.4 90.6 3.5 4.7 21.2 18.4 8.2 56.7 13.9 27.5 8.0 9.3 5.1 6.6 6.9 18.1 5.7 12.5 49.4 9.1 5.6 90.3 21.5 27.5 14.9 CXCR5 "BLR1, CD185, MDR15" ENSG00000160683 "C-X-C motif chemokine receptor 5" P32302 11 118883892-118897787 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "B-cell activation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 10.6;intestine: 10.2;lymphoid tissue: 28.9" "Cell type enriched" "Detected in some" 13 "B-cells: 83.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "memory B-cell: 67.7;naive B-cell: 92.4" "Lineage enriched" "Detected in many" 8 "B-cells: 92.4" "Group enriched" "Detected in some" 11 "Daudi: 18.9;U-698: 65.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026149, HPA042432" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB026149: , HPA042432: AB_2677995" "unprognostic (8.51e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-1)" "unprognostic (4.02e-5)" "unprognostic (2.08e-2)" "unprognostic (3.23e-3)" "unprognostic (1.19e-2)" "unprognostic (3.66e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-5)" "unprognostic (4.21e-1)" "unprognostic (2.03e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" 0.5 1.9 0.4 11.2 0.3 10.6 0.2 0.7 0.5 2.7 0.0 4.4 0.4 0.3 0.1 2.5 0.1 1.0 0.9 0.4 0.2 2.1 1.5 1.4 28.9 0.3 0.4 0.7 0.9 0.0 1.0 0.2 0.3 3.7 0.4 0.6 1.3 0.0 2.1 1.9 10.2 0.0 0.1 21.1 2.0 0.3 0.5 1.9 0.8 0.0 15.9 2.3 1.4 0.0 0.1 0.0 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 18.9 0.5 0.0 0.7 2.1 0.0 0.0 0.0 0.4 0.3 3.9 0.0 0.0 0.0 0.5 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.9 0.0 0.6 0.0 1.1 0.8 1.6 0.0 0.7 0.0 0.8 0.1 0.3 0.0 0.0 0.6 0.5 0.0 0.1 0.9 0.2 0.4 0.8 0.0 0.6 0.9 0.0 0.2 0.3 0.0 65.2 0.1 0.7 0.0 0.1 0.1 0.0 1.0 0.0 0.9 67.7 10.9 3.0 0.1 92.4 1.1 1.0 0.1 0.2 0.1 0.1 1.7 6.2 0.4 0.3 0.7 0.5 0.4 0.2 0.3 0.4 0.3 0.1 0.5 0.0 0.1 0.0 1.8 0.0 83.0 0.1 0.0 0.0 1.2 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.5 1.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.2 1.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.9 0.6 0.3 6.1 0.1 0.1 0.1 CXorf38 MGC39350 ENSG00000185753 "Chromosome X open reading frame 38" Q8TB03 X 40626921-40647561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050120 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA050120: AB_2681024" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.91e-1)" "unprognostic (6.98e-2)" "unprognostic (1.37e-1)" "unprognostic (3.15e-1)" "unprognostic (1.48e-3)" "unprognostic (7.59e-2)" "unprognostic (1.46e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (7.30e-4)" "unprognostic (1.23e-1)" "unprognostic (1.71e-3)" "unprognostic (2.87e-2)" "unprognostic (1.23e-1)" "unprognostic (4.73e-2)" "prognostic favorable (1.44e-8)" 9.0 8.2 5.1 11.5 5.9 10.5 8.2 5.8 5.3 8.0 4.5 7.6 8.3 7.3 4.6 6.1 10.0 6.4 4.8 4.9 5.3 8.1 8.0 10.2 16.1 6.2 5.6 9.5 6.0 9.5 4.8 6.8 6.3 6.3 7.7 5.7 6.5 6.1 5.0 7.9 9.7 5.8 5.8 14.4 6.6 2.1 5.9 13.2 11.1 4.1 13.4 7.2 7.0 7.0 11.3 5.9 6.2 4.9 6.5 10.8 3.3 7.5 10.5 9.1 9.1 7.7 15.8 18.5 6.4 11.2 15.2 7.4 7.6 12.5 8.3 25.7 11.4 12.5 7.1 4.6 10.8 22.0 18.6 9.6 9.0 12.7 12.5 8.7 10.4 15.8 5.3 13.7 17.0 10.5 15.4 16.7 5.6 8.2 12.8 12.7 13.2 14.4 10.7 17.0 7.0 9.6 15.1 7.5 8.9 11.6 11.4 10.1 13.0 11.9 6.8 8.7 6.5 14.7 5.5 7.9 15.4 11.4 8.0 9.3 16.0 22.1 9.2 15.8 9.7 6.9 8.7 7.4 14.2 9.6 7.6 7.8 19.7 7.3 25.1 5.9 10.9 10.3 5.1 5.9 5.8 5.3 4.9 5.3 6.2 5.6 6.3 5.8 5.9 7.0 19.8 9.6 9.1 10.1 26.9 3.6 11.3 6.3 10.8 12.6 10.5 8.0 6.4 18.6 7.6 16.5 18.8 9.2 48.3 15.1 7.9 27.7 1.0 25.2 15.0 14.0 7.3 6.3 11.9 30.1 9.7 8.9 9.7 21.6 17.1 16.5 10.4 10.8 36.6 15.2 13.1 12.7 8.2 30.7 9.8 1.3 9.6 29.5 3.6 8.4 61.9 10.2 41.2 12.1 17.8 40.5 17.2 5.3 16.4 14.7 15.8 14.4 7.8 7.6 6.6 13.5 9.2 6.5 7.4 9.7 5.4 8.2 31.2 20.6 13.3 28.3 CYSLTR1 "CysLT(1), CysLT1, CYSLT1R" ENSG00000173198 "Cysteinyl leukotriene receptor 1" Q9Y271 X 78271468-78327691 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.3;Alveolar cells type 2: 68.4;B-cells: 64.1;dendritic cells: 44.7;granulocytes: 78.6;Plasma cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 85.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 19.8;Karpas-707: 12.4;NB-4: 27.1;RPMI-8226: 41.9;THP-1: 25.2;U-937: 28.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010546 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "HPA010546: AB_1078268" "unprognostic (9.48e-2)" "unprognostic (6.01e-5)" "unprognostic (4.72e-3)" "unprognostic (3.04e-1)" "unprognostic (6.30e-2)" "unprognostic (2.80e-3)" "unprognostic (2.52e-1)" "unprognostic (8.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.53e-2)" "unprognostic (4.55e-1)" "unprognostic (2.43e-1)" "unprognostic (4.41e-4)" "unprognostic (5.82e-2)" "unprognostic (3.56e-2)" "unprognostic (9.87e-2)" "unprognostic (8.94e-2)" 4.7 1.7 0.6 7.6 0.6 3.5 2.3 0.7 0.8 2.6 0.8 3.6 2.4 1.7 0.7 7.3 1.7 5.6 1.7 0.6 0.8 1.0 1.6 7.3 9.5 1.0 0.7 0.4 0.6 1.4 0.3 3.5 1.0 2.3 4.9 0.3 1.9 1.0 0.5 3.3 3.9 4.5 1.0 10.6 2.9 0.2 0.7 4.1 2.0 1.8 11.6 6.9 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 19.8 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 27.1 0.1 0.0 0.0 5.7 0.0 41.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 25.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.1 28.1 0.0 19.5 15.1 85.8 0.0 26.5 0.1 19.1 5.5 0.2 11.7 15.2 8.3 0.1 45.2 10.6 31.2 18.0 1.4 6.9 0.6 0.6 0.7 0.8 0.6 0.8 1.0 0.7 1.0 1.0 0.7 0.9 20.4 67.3 68.4 0.7 64.1 3.7 3.7 0.6 5.2 3.7 1.6 0.9 1.4 0.0 36.7 0.0 6.2 0.3 44.7 1.1 0.0 0.2 0.0 0.3 0.3 21.5 0.0 3.8 0.5 0.2 0.3 7.6 0.0 0.3 78.6 1.3 5.7 0.3 29.8 0.0 0.3 0.3 2.0 39.3 14.7 0.0 0.6 37.5 7.2 16.9 21.4 0.5 23.7 0.0 0.0 0.2 0.0 0.0 44.9 1.4 1.7 0.5 35.9 0.7 0.0 0.7 3.2 0.1 0.3 1.4 3.7 0.8 20.6 0.2 0.5 3.4 DENND4B KIAA0476 ENSG00000198837 "DENN domain containing 4B" O75064 1 153929501-153946718 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040188, HPA071133" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Golgi apparatus" "HPA040188: AB_10671168, HPA071133: AB_2732173" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (1.59e-2)" "unprognostic (9.42e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-3)" "prognostic unfavorable (4.14e-4)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.18e-5)" "unprognostic (2.21e-1)" "prognostic unfavorable (9.27e-9)" "unprognostic (4.24e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.56e-3)" 18.2 13.4 10.9 24.3 11.1 37.1 15.7 2.3 19.1 17.1 0.0 15.6 9.5 16.3 3.4 10.2 16.2 10.0 21.3 10.2 6.5 13.8 11.4 24.2 30.1 12.0 7.8 19.6 15.5 7.7 13.1 10.3 13.0 13.0 6.0 9.5 11.7 7.0 49.2 11.0 22.0 8.9 3.1 41.0 12.9 7.6 9.8 14.6 15.2 29.5 17.3 15.1 12.9 10.0 12.0 22.7 17.1 17.3 10.0 9.7 17.8 11.5 12.4 17.8 16.6 13.8 13.4 29.9 19.1 7.8 13.5 20.9 15.5 10.6 8.0 27.5 14.0 26.5 26.1 13.3 13.9 28.0 51.5 8.8 18.3 16.6 17.8 14.8 12.8 32.3 28.7 16.4 10.3 24.6 34.2 25.7 23.8 14.1 21.8 36.2 11.5 17.3 8.5 17.6 20.3 24.9 12.1 28.4 16.7 17.0 20.6 68.0 13.5 19.2 18.5 16.1 18.7 49.3 37.7 39.5 13.2 21.7 23.5 1.5 1.6 0.4 1.1 2.4 1.4 1.0 0.9 0.7 1.4 0.9 0.4 1.0 1.5 0.7 1.9 1.9 0.7 1.5 10.9 11.1 2.3 19.1 10.2 6.5 12.0 7.8 13.0 3.1 9.8 10.0 14.7 9.6 10.3 18.6 20.3 4.7 3.7 4.6 1.2 22.3 7.1 6.9 22.9 8.6 5.7 7.3 6.2 4.6 31.9 4.8 5.9 5.2 1.2 4.0 8.0 11.8 4.9 9.5 21.8 6.5 4.7 7.2 13.7 7.4 17.2 12.5 10.8 9.2 18.0 35.3 23.6 4.6 2.0 30.2 11.7 1.9 7.5 31.1 5.4 18.7 22.5 5.8 30.9 19.1 27.9 6.1 4.8 7.9 7.1 6.8 7.6 2.7 4.4 17.8 6.6 7.9 6.0 6.4 8.1 5.7 3.4 3.4 17.0 9.2 7.1 5.2 DNAAF2 "C14orf104, CILD10, FLJ10563, KTU, PF13" ENSG00000165506 "Dynein axonemal assembly factor 2" Q9NVR5 14 49625174-49635244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002894, HPA004113" Enhanced Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 57: B-cells - Immune response" Cytosol "HPA002894: AB_1078316, HPA004113: AB_1078315" "unprognostic (3.88e-2)" "unprognostic (2.11e-1)" "unprognostic (7.57e-2)" "unprognostic (5.85e-2)" "unprognostic (1.19e-2)" "unprognostic (1.65e-1)" "unprognostic (9.50e-2)" "unprognostic (1.75e-2)" "unprognostic (2.53e-2)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "unprognostic (2.25e-2)" "prognostic favorable (6.74e-7)" "unprognostic (6.72e-2)" "unprognostic (2.54e-1)" "unprognostic (5.04e-2)" "unprognostic (3.44e-2)" 3.8 4.6 3.2 4.4 3.1 3.4 5.7 3.8 3.3 4.3 6.0 5.4 7.6 4.0 4.1 4.4 8.6 3.7 4.3 3.0 3.5 6.8 9.3 3.7 5.5 3.5 4.3 3.5 6.9 3.9 3.4 3.4 3.5 4.0 4.7 4.8 5.5 3.0 5.0 3.2 6.2 3.3 3.6 4.1 5.1 6.3 3.4 4.7 5.3 5.3 4.6 4.6 3.3 3.6 14.2 8.3 18.0 14.1 8.6 9.9 17.1 7.5 8.3 8.2 9.0 8.1 13.4 20.7 11.6 5.0 6.7 15.3 15.0 10.6 10.2 14.6 8.9 10.6 6.2 14.1 6.7 17.3 8.6 6.6 11.3 7.0 9.5 8.4 8.5 11.3 16.0 13.8 8.2 17.7 11.4 17.8 19.6 14.7 15.1 14.0 13.9 7.0 11.7 11.8 27.4 20.4 11.2 12.0 13.8 11.3 13.7 6.9 7.0 7.6 21.7 7.9 9.5 27.5 18.4 17.1 2.9 10.5 8.5 7.8 4.9 6.8 7.4 4.5 8.9 11.6 8.2 9.9 5.7 9.3 7.9 7.8 1.8 12.4 5.8 5.1 8.5 4.8 3.2 3.1 3.8 3.3 3.0 3.5 3.5 4.3 3.5 3.6 3.4 3.6 9.8 3.2 5.6 5.9 38.5 41.0 25.0 38.9 41.5 7.0 21.4 20.3 10.6 15.7 14.6 12.9 0.0 21.6 16.2 13.0 31.3 28.4 25.9 30.3 22.9 17.1 9.6 13.9 6.8 24.0 29.4 17.6 19.4 13.8 12.0 12.2 19.2 26.6 14.0 3.3 8.0 15.3 48.8 9.2 21.1 7.5 18.3 10.2 19.6 2.8 10.5 11.3 19.6 6.6 6.2 25.7 13.0 16.6 43.7 36.2 30.8 37.9 27.2 11.9 6.6 16.0 15.4 22.4 17.9 38.6 44.0 12.4 28.0 30.2 22.8 20.0 DRAM2 "MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154" ENSG00000156171 "DNA damage regulated autophagy modulator 2" Q6UX65 1 111117163-111140203 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018036, HPA061701" Supported Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Vesicles" "HPA018036: AB_1858134, HPA061701: AB_2684590" "unprognostic (9.38e-3)" "unprognostic (1.58e-2)" "unprognostic (2.16e-3)" "unprognostic (5.22e-2)" "unprognostic (1.12e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.57e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.69e-1)" "unprognostic (4.37e-3)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (1.77e-3)" 38.0 23.1 13.9 33.1 14.5 17.9 26.8 17.7 19.9 23.1 22.7 26.7 28.6 17.7 17.6 15.0 30.1 36.4 23.7 13.5 15.2 26.5 24.9 25.0 55.3 15.6 14.9 24.3 25.6 28.3 4.6 41.2 16.2 17.8 30.7 16.9 25.8 16.7 16.6 17.9 26.3 17.0 15.5 45.3 23.4 10.3 15.0 27.8 22.0 23.6 50.3 29.4 4.2 17.8 38.0 12.9 24.0 10.8 57.3 56.2 23.4 28.7 29.9 24.7 24.9 12.5 38.2 28.7 17.2 25.6 12.1 37.4 30.5 24.0 31.9 26.8 25.6 16.8 18.4 16.4 41.4 19.4 15.4 38.5 41.4 18.3 38.4 53.6 29.9 29.1 34.1 19.6 30.1 19.6 16.6 28.8 14.5 43.3 13.2 11.1 40.0 14.0 42.5 25.8 19.1 18.2 16.8 52.4 80.1 33.1 16.7 84.6 24.8 20.6 13.8 16.2 18.9 25.7 9.6 29.8 33.4 34.7 29.6 41.7 47.3 11.5 14.2 61.0 19.4 65.7 17.5 15.3 45.1 54.1 22.3 19.0 7.2 25.0 49.8 28.6 17.7 35.5 13.9 14.5 17.7 19.9 13.5 15.2 15.6 14.9 16.2 15.5 15.0 17.8 34.5 12.8 12.0 17.3 146.2 47.0 54.4 82.5 34.1 11.6 53.6 43.9 29.7 32.9 53.1 44.1 2.1 98.1 38.9 41.2 43.0 59.2 8.5 51.7 19.5 36.4 13.2 28.6 20.6 46.6 102.3 39.2 24.5 17.6 23.6 18.5 42.8 26.0 183.1 20.2 31.7 45.7 77.3 189.4 97.8 7.8 33.5 110.3 81.8 39.4 89.0 27.1 56.7 31.7 42.6 41.9 64.3 24.8 54.7 46.3 88.4 80.4 95.8 10.1 39.5 26.4 32.5 4.7 14.6 40.8 53.0 73.3 38.6 26.3 43.7 70.1 E2F5 ENSG00000133740 "E2F transcription factor 5" Q15329 8 85177154-85217158 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.6" "Cell type enhanced" "Detected in many" "B-cells: 23.7;Plasma cells: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 13.4;naive B-cell: 8.9" "Lineage enriched" "Detected in many" 9 "B-cells: 13.4" "Cell line enhanced" "Detected in many" "AF22: 82.6;Daudi: 158.0;U-698: 77.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055723, HPA065441" Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli, Vesicles" "HPA055723: AB_2682897, HPA065441: " "unprognostic (8.73e-2)" "unprognostic (3.45e-1)" "unprognostic (3.15e-2)" "unprognostic (1.02e-3)" "unprognostic (6.73e-3)" "unprognostic (1.62e-1)" "unprognostic (3.36e-5)" "unprognostic (1.23e-1)" "unprognostic (9.53e-2)" "unprognostic (1.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (1.89e-6)" "unprognostic (2.88e-2)" "unprognostic (3.25e-2)" "unprognostic (3.64e-1)" "unprognostic (2.95e-3)" 1.8 3.9 4.8 8.0 5.2 1.7 6.7 4.6 6.5 5.2 5.1 6.6 4.9 4.5 8.1 2.2 8.0 4.3 1.9 5.1 5.8 8.1 3.0 4.1 25.9 5.5 5.2 4.9 4.3 13.2 3.7 5.0 5.0 3.6 7.8 0.9 2.3 3.3 0.4 0.8 3.8 4.1 5.1 6.9 5.5 8.5 5.3 10.7 8.7 0.9 29.6 6.9 0.9 5.5 14.2 15.9 82.6 29.7 1.5 2.2 25.0 2.7 6.9 2.4 7.4 9.6 17.4 158.0 10.3 3.5 28.4 2.6 51.0 4.3 3.0 16.0 20.1 16.4 8.3 22.4 13.4 4.8 0.1 3.3 6.9 3.5 12.0 15.7 2.7 16.5 34.7 1.2 4.6 10.0 15.8 10.8 26.1 28.0 12.9 12.9 3.4 17.9 27.5 10.7 9.8 29.8 1.8 5.8 23.8 32.6 33.5 5.2 0.1 3.7 2.5 4.6 10.5 27.6 20.6 77.1 4.3 4.1 8.0 0.0 0.0 0.0 0.1 0.0 0.0 13.4 0.0 0.0 0.1 8.9 0.2 0.4 0.0 1.4 0.0 1.5 0.6 0.6 4.8 5.2 4.6 6.5 5.1 5.8 5.5 5.2 5.0 5.1 5.3 5.5 1.1 0.0 6.5 3.6 23.7 2.3 3.3 1.3 1.2 0.9 5.6 6.0 1.0 5.7 2.9 5.5 10.4 4.1 5.1 3.3 0.0 3.3 7.6 7.3 5.2 1.5 7.8 1.3 7.7 2.6 1.1 3.0 4.1 7.5 1.3 5.5 0.4 2.4 0.5 0.0 4.6 2.7 2.0 0.8 1.0 3.8 1.5 1.9 3.6 4.7 0.3 5.2 4.1 11.6 4.2 3.0 1.7 1.9 29.6 6.9 0.8 5.8 8.6 1.6 0.0 5.0 4.5 8.1 4.6 2.3 2.8 1.1 2.5 4.6 3.7 2.1 FAM167A "C8orf13, DIORA-1" ENSG00000154319 "Family with sequence similarity 167 member A" Q96KS9 8 11421476-11475908 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.1;thyroid gland: 53.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 28.4;Distal tubular cells: 13.7;Early spermatids: 24.8;Enteroendocrine cells: 19.1;Late spermatids: 41.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 16.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 57.6;RPMI-8226: 61.5;SH-SY5Y: 44.4;U-698: 44.8;U-87 MG: 36.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023915, HPA030426" Approved Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA023915: AB_1845768, HPA030426: AB_10601318" "unprognostic (8.51e-3)" "unprognostic (2.43e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (5.96e-4)" "unprognostic (3.08e-2)" "unprognostic (4.62e-3)" "unprognostic (1.79e-1)" "unprognostic (1.45e-1)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (4.06e-2)" "unprognostic (7.17e-2)" "unprognostic (1.77e-2)" "unprognostic (7.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.30e-2)" "unprognostic (2.21e-2)" 0.6 0.8 25.8 1.2 25.1 0.7 1.3 23.9 25.3 0.8 17.0 0.7 0.3 0.1 0.5 0.9 1.3 1.0 0.2 26.6 26.7 6.4 0.3 10.2 2.4 29.8 27.6 0.0 2.1 1.7 17.4 0.9 27.9 1.5 0.7 5.2 2.6 4.6 0.0 11.8 1.3 0.0 26.6 1.2 2.0 3.8 31.1 3.0 53.2 0.1 3.0 0.3 1.6 25.1 4.8 3.0 6.1 0.6 0.4 2.5 0.2 16.8 16.0 10.1 4.4 0.2 1.5 57.6 0.9 18.3 4.7 1.6 0.1 4.0 11.9 24.8 0.8 0.0 0.1 0.0 20.8 0.0 0.1 2.9 2.6 5.3 32.2 32.3 0.0 0.0 0.2 2.2 6.0 1.8 0.1 0.0 1.6 0.1 0.1 0.3 0.0 61.5 5.1 0.5 26.3 44.4 0.8 4.7 2.2 0.8 1.8 0.1 28.5 1.0 1.6 25.8 0.2 17.7 14.0 44.8 36.3 0.1 1.6 0.0 0.0 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.5 0.4 0.0 0.0 25.8 25.1 23.9 25.3 26.6 26.7 29.8 27.6 27.9 26.6 31.1 25.1 0.0 16.0 1.8 28.4 5.4 5.9 0.6 0.5 0.0 0.1 1.2 1.3 0.7 1.5 0.5 5.5 10.4 0.0 1.1 0.2 13.7 2.1 24.8 2.1 0.2 0.2 19.1 0.0 0.6 1.8 0.0 0.3 2.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.4 1.3 0.0 0.3 0.3 41.1 0.3 0.3 0.0 3.7 0.3 1.7 0.0 0.0 1.3 1.1 2.4 0.4 0.9 0.8 0.1 0.2 1.9 1.8 0.0 0.3 0.2 3.9 2.2 0.0 3.4 0.0 1.0 0.1 0.1 0.2 FCER2 "CD23, CD23A, CLEC4J, FCE2" ENSG00000104921 "Fc fragment of IgE receptor II" P06734 19 7688758-7702146 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgE-binding protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 42.2" "Cell type enriched" "Detected in some" 16 "B-cells: 157.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in many" 24 "memory B-cell: 200.9;naive B-cell: 496.2" "Lineage enriched" "Detected in many" 34 "B-cells: 496.2" "Cell line enriched" "Detected in some" 14 "HDLM-2: 449.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002624, HPA008928, HPA067430" Enhanced "Secreted to blood" NA NA 240000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "CAB002624: , HPA008928: AB_1846285, HPA067430: " "unprognostic (3.20e-4)" "unprognostic (1.87e-3)" "unprognostic (1.95e-2)" "unprognostic (2.44e-2)" "unprognostic (4.77e-2)" "unprognostic (1.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.89e-3)" "unprognostic (2.71e-1)" "unprognostic (1.88e-1)" "unprognostic (2.04e-2)" "unprognostic (8.55e-2)" "unprognostic (2.46e-4)" "unprognostic (2.99e-1)" "unprognostic (1.80e-1)" "unprognostic (4.89e-2)" "unprognostic (5.17e-2)" 4.8 0.1 0.0 17.4 0.0 5.2 1.2 0.2 1.3 0.4 0.0 1.8 2.8 0.1 0.1 0.4 0.3 1.1 0.5 0.3 0.0 0.3 0.5 0.6 39.5 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.1 1.9 0.0 1.8 0.1 0.3 0.4 9.7 0.2 0.0 38.4 2.2 0.4 0.0 6.3 0.6 0.1 42.2 1.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 449.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 0.1 32.7 0.0 0.5 4.2 0.3 0.0 14.7 0.1 200.9 0.2 0.0 4.4 496.2 0.3 0.1 1.5 0.3 4.4 0.6 0.2 21.6 0.0 0.0 0.2 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 157.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.1 0.0 1.2 0.0 0.1 0.0 0.0 1.3 1.7 0.0 0.0 9.4 1.8 1.0 0.9 0.0 2.1 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 1.2 1.2 0.0 0.0 FCHO1 KIAA0290 ENSG00000130475 "FCH and mu domain containing endocytic adaptor 1" O14526 19 17747718-17788568 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;lymphoid tissue: 24.3;skin 1: 22.2" "Cell type enhanced" "Detected in many" "B-cells: 16.8;dendritic cells: 19.1;Oligodendrocytes: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 62.4;RPMI-8226: 43.3;U-937: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041653, HPA062981" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA041653: AB_10795641, HPA062981: AB_2684915" "unprognostic (3.02e-1)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (4.54e-3)" "unprognostic (3.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (5.48e-3)" "unprognostic (1.72e-9)" "unprognostic (3.76e-3)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (9.77e-3)" 2.2 1.8 24.9 14.7 33.7 20.2 1.5 21.7 32.6 1.0 8.6 2.5 3.2 1.3 1.4 1.1 1.5 4.2 0.8 24.1 25.6 1.4 2.2 3.7 24.3 27.5 28.6 1.7 0.7 1.1 3.9 1.1 29.7 1.0 2.2 3.4 1.3 0.8 0.6 22.2 8.1 1.7 19.9 15.5 3.4 4.4 29.2 17.6 1.0 0.8 17.4 3.0 1.0 59.5 0.9 11.9 7.5 5.2 0.2 0.2 7.5 1.1 0.3 0.3 0.5 1.5 1.4 62.4 17.1 0.5 1.4 2.3 3.7 2.3 0.2 27.6 2.1 4.9 1.4 6.4 0.6 15.7 10.2 0.1 0.3 0.0 0.4 0.4 1.6 30.2 24.9 28.9 0.0 17.4 36.2 27.8 3.6 14.7 28.7 30.2 0.2 43.3 0.2 1.2 1.3 2.5 0.3 5.9 0.9 0.9 6.0 15.4 1.3 0.1 4.1 0.9 0.4 18.2 9.0 33.4 0.9 38.5 0.5 13.2 9.6 10.1 7.0 14.3 6.0 12.4 7.9 6.3 14.5 12.3 7.4 6.1 37.8 6.4 11.5 15.3 7.6 7.4 24.9 33.7 21.7 32.6 24.1 25.6 27.5 28.6 29.7 19.9 29.2 59.5 0.4 0.0 1.5 0.7 16.8 0.0 0.4 0.2 0.6 7.8 2.0 4.3 0.9 2.8 0.4 1.8 0.0 2.9 19.1 2.0 0.0 0.5 1.5 0.8 0.2 2.4 1.2 2.5 15.0 0.0 4.6 2.5 1.5 1.0 9.5 2.9 2.5 0.0 6.8 0.0 13.0 1.7 0.0 8.7 14.3 0.7 2.5 11.0 1.8 6.5 12.3 0.1 13.4 3.0 46.9 2.1 0.5 8.6 4.5 0.3 0.1 0.1 0.7 0.8 0.0 0.2 0.6 0.9 5.5 0.2 0.6 0.8 9.8 12.2 1.8 0.3 FCMR "FAIM3, TOSO" ENSG00000162894 "Fc fragment of IgM receptor" O60667 1 206903317-206923247 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 65.5;lymphoid tissue: 180.6" "Cell type enhanced" "Detected in many" "B-cells: 262.3;dendritic cells: 43.5;NK-cells: 108.1;T-cells: 74.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "RPMI-8226: 171.4;U-266/70: 73.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003910 Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 5500000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA003910: AB_1078798" "prognostic favorable (4.23e-4)" "unprognostic (1.16e-3)" "unprognostic (7.48e-2)" "unprognostic (3.06e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-3)" "unprognostic (1.15e-1)" "unprognostic (4.85e-3)" "unprognostic (1.03e-1)" "unprognostic (3.97e-1)" "unprognostic (3.23e-2)" "unprognostic (2.01e-1)" "unprognostic (8.15e-3)" "unprognostic (8.06e-2)" "unprognostic (2.12e-2)" "unprognostic (3.74e-2)" "unprognostic (5.05e-3)" 4.9 1.5 0.3 74.8 0.3 12.6 2.4 0.3 0.8 1.5 0.4 8.0 6.1 2.4 2.6 3.0 1.9 11.3 2.6 0.1 0.4 2.3 5.9 6.0 152.1 0.4 0.1 0.8 1.1 0.5 1.0 1.8 0.2 3.4 9.9 0.2 3.5 1.2 3.6 0.4 65.5 2.3 0.0 115.0 14.2 0.5 0.5 77.2 3.3 1.4 180.6 19.1 1.6 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 3.4 0.3 0.3 0.0 0.0 11.6 0.0 0.4 0.7 0.3 0.0 0.6 0.5 0.0 0.2 0.2 0.9 0.0 1.6 0.1 0.0 0.1 0.7 0.3 1.2 0.0 0.0 7.0 0.2 23.5 0.0 0.2 3.5 0.3 0.1 0.0 0.2 4.9 0.6 171.4 0.1 0.3 0.1 0.0 2.8 0.6 13.0 0.0 0.3 0.0 0.5 0.0 0.5 0.2 0.1 73.8 5.9 23.2 0.8 0.1 0.6 7.9 2.8 3.6 209.3 4.3 276.9 882.3 280.1 266.3 3.2 1057.5 483.2 336.0 56.0 218.8 4.3 13.7 687.7 416.6 0.3 0.3 0.3 0.8 0.1 0.4 0.4 0.1 0.2 0.0 0.5 0.6 1.3 0.0 3.9 0.0 262.3 0.0 4.9 0.0 1.2 0.0 3.5 3.0 3.6 5.7 1.3 0.0 0.0 0.1 43.5 0.9 0.0 1.7 0.2 0.8 0.7 1.7 0.0 8.4 0.0 2.9 0.1 3.4 4.1 0.9 0.0 0.6 4.6 1.4 4.4 0.0 0.0 0.6 0.0 5.7 0.0 0.4 0.3 8.1 0.0 0.0 3.6 0.0 108.1 0.0 0.0 1.2 0.3 0.0 30.5 2.9 0.1 1.0 0.7 0.0 0.0 0.2 2.9 0.1 2.3 1.7 0.0 0.0 74.9 0.0 1.9 6.8 FCRL1 "CD307a, FCRH1, IFGP1, IRTA5" ENSG00000163534 "Fc receptor like 1" Q96LA6 1 157794403-157820120 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "bone marrow: 8.0;intestine: 8.6;lymphoid tissue: 27.3" "Cell type enriched" "Detected in some" 26 "B-cells: 88.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 39.3;naive B-cell: 68.1" "Lineage enriched" "Detected in many" 62 "B-cells: 68.1" "Group enriched" "Detected in some" 26 "Daudi: 5.4;U-698: 17.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013323 Enhanced NA NA 290000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA013323: AB_1848480" "unprognostic (6.52e-4)" "unprognostic (3.49e-3)" "unprognostic (8.68e-3)" "unprognostic (8.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.01e-5)" "unprognostic (1.47e-2)" "unprognostic (5.48e-3)" "unprognostic (1.40e-2)" "unprognostic (4.30e-2)" "unprognostic (1.81e-1)" "unprognostic (2.85e-2)" "unprognostic (1.44e-3)" "unprognostic (1.96e-1)" "unprognostic (1.65e-2)" "unprognostic (4.80e-2)" "unprognostic (6.74e-2)" 0.2 0.0 0.0 10.1 0.0 8.0 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.2 0.2 0.6 27.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.0 0.6 0.0 0.0 0.0 8.6 0.0 0.0 17.8 0.8 0.0 0.0 3.0 0.4 0.0 22.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 39.3 0.0 0.0 0.0 68.1 0.0 0.1 1.1 0.2 0.5 0.0 0.3 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.7 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.5 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 FCRL2 "CD307b, FCRH2, IRTA4, SPAP1" ENSG00000132704 "Fc receptor like 2" Q96LA5 1 157745733-157777132 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "intestine: 20.9;lymphoid tissue: 34.3" "Group enriched" "Detected in some" 17 "B-cells: 84.7;Plasma cells: 40.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 29.7;naive B-cell: 18.4" "Lineage enriched" "Detected in single" 42 "B-cells: 29.7" "Group enriched" "Detected in some" 4 "Daudi: 12.9;U-698: 10.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (3.94e-3)" "unprognostic (1.47e-3)" "unprognostic (3.49e-2)" "unprognostic (3.69e-3)" "unprognostic (5.11e-5)" "unprognostic (1.67e-2)" "unprognostic (4.77e-3)" "unprognostic (8.19e-2)" "unprognostic (8.66e-3)" "unprognostic (1.20e-2)" "unprognostic (4.19e-2)" "unprognostic (4.60e-7)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (7.92e-2)" "unprognostic (2.48e-1)" 0.4 0.0 0.1 12.3 0.1 2.6 0.4 0.0 0.4 0.2 0.0 2.2 2.2 0.1 0.1 0.4 0.1 1.0 0.4 0.1 0.2 0.4 0.4 0.7 24.1 0.4 0.1 0.4 0.0 0.0 0.0 0.1 0.2 0.3 2.7 0.2 1.0 0.0 0.0 0.2 20.9 0.1 0.1 34.3 1.7 0.3 0.2 1.7 0.5 0.0 25.8 1.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.7 0.0 10.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 29.7 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.4 0.1 0.2 0.4 0.1 0.2 0.1 0.2 0.8 0.0 0.0 1.1 0.0 84.7 0.3 0.5 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.3 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.3 1.3 0.0 0.7 0.6 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 1.0 3.6 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.1 0.0 40.4 0.3 0.0 0.1 0.1 0.0 0.0 1.2 0.6 0.0 0.2 0.0 0.4 0.1 1.9 0.0 0.1 0.4 FCRL3 "CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e" ENSG00000160856 "Fc receptor like 3" Q96P31 1 157674321-157700769 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 49.5" "Cell type enhanced" "Detected in some" "B-cells: 54.3;dendritic cells: 21.2;Early spermatids: 8.0;Late spermatids: 9.1;NK-cells: 30.9;T-cells: 12.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive B-cell: 35.3" "Group enriched" "Detected in many" 54 "B-cells: 35.3;NK-cells: 20.4;T-cells: 19.0" "Cell line enriched" "Detected in some" 7 "Daudi: 9.9" "Low region specificity" "Detected in some" HPA048022 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA048022: AB_2732541" "unprognostic (6.73e-3)" "unprognostic (5.06e-4)" "unprognostic (1.13e-2)" "unprognostic (2.08e-4)" "unprognostic (3.86e-1)" "unprognostic (1.74e-5)" "unprognostic (1.09e-2)" "unprognostic (4.29e-3)" "unprognostic (3.69e-3)" "unprognostic (2.46e-4)" "unprognostic (1.13e-1)" "unprognostic (2.55e-2)" "unprognostic (2.01e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (6.69e-2)" 0.4 0.0 0.0 14.1 0.0 1.1 0.1 0.0 0.0 0.1 0.0 1.1 0.3 0.2 0.1 0.1 0.1 1.0 0.2 0.0 0.0 0.2 0.8 0.9 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.8 0.0 0.1 0.0 8.7 0.1 0.0 27.5 1.5 0.2 0.0 4.6 0.4 0.1 36.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 19.0 0.0 1.8 30.3 2.6 13.2 0.0 35.3 0.2 8.3 0.4 20.4 0.0 0.0 11.3 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 54.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.0 1.2 0.0 9.1 0.0 0.4 0.0 1.0 0.9 0.0 30.9 0.5 0.0 0.0 1.1 0.0 3.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 FCRL4 "CD307d, FCRH4, IGFP2, IRTA1" ENSG00000163518 "Fc receptor like 4" Q96PJ5 1 157573747-157598085 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.5" "Cell type enhanced" "Detected in single" "B-cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 47 "U-266/70: 4.6" "Not detected" "Not detected" HPA054030 Approved NA NA "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA054030: " "unprognostic (6.06e-2)" "unprognostic (3.41e-3)" "unprognostic (2.57e-1)" "unprognostic (5.08e-2)" "unprognostic (4.69e-4)" "unprognostic (2.06e-2)" "unprognostic (6.38e-2)" "unprognostic (1.99e-1)" "unprognostic (2.14e-1)" "unprognostic (3.37e-1)" "unprognostic (6.77e-2)" 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.3 0.0 0.0 0.2 0.0 0.0 10.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 FCRLA "FCRL, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595" ENSG00000132185 "Fc receptor like A" Q7L513 1 161706972-161714352 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 98.4" "Group enriched" "Detected in some" 6 "B-cells: 124.2;Melanocytes: 67.6" "Cancer enriched" "Detected in many" 21 "melanoma: 38.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "memory B-cell: 368.0;naive B-cell: 341.5" "Lineage enriched" "Detected in many" 10 "B-cells: 368.0" "Group enriched" "Detected in some" 6 "Daudi: 484.1;SK-MEL-30: 197.8;U-698: 260.5" "Not detected" "Not detected" "Not detected" "Not detected" CAB016545 Enhanced "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB016545: AB_2247037" "unprognostic (5.46e-4)" "unprognostic (7.19e-2)" "unprognostic (3.69e-3)" "unprognostic (4.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.48e-4)" "unprognostic (1.45e-2)" "unprognostic (4.15e-3)" "unprognostic (8.66e-2)" "unprognostic (3.58e-4)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (6.84e-5)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (2.08e-2)" 0.8 0.2 0.5 23.5 0.3 4.1 0.5 1.1 0.7 0.3 0.3 2.6 0.9 0.4 0.6 0.5 0.1 1.1 0.6 0.4 0.2 0.3 0.4 0.6 68.5 0.3 0.3 0.2 0.0 0.0 0.0 0.3 0.3 0.8 2.8 0.3 2.3 0.1 0.3 1.2 19.1 0.4 0.1 38.5 4.1 0.2 0.5 7.7 0.5 0.3 98.4 3.4 0.1 0.4 0.7 0.0 0.0 0.0 0.4 0.4 0.0 2.7 7.4 0.2 0.5 0.0 0.0 484.1 0.2 7.0 0.0 0.1 0.0 0.7 0.8 1.8 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.4 0.5 2.4 0.4 0.1 0.0 0.0 0.9 26.7 0.1 0.0 0.1 0.3 0.1 0.0 0.1 4.0 8.3 52.4 0.0 0.1 0.0 0.0 0.3 0.1 197.8 0.0 0.0 0.2 0.5 0.6 0.7 0.5 0.5 0.7 0.3 260.5 2.9 0.3 44.3 0.4 0.3 0.2 0.8 0.0 0.1 368.0 0.2 0.4 0.4 341.5 0.2 0.1 0.6 0.2 0.2 38.4 0.2 17.0 0.5 0.3 1.1 0.7 0.4 0.2 0.3 0.3 0.3 0.1 0.5 0.4 0.0 0.0 0.6 0.0 124.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.7 67.6 0.0 0.4 0.0 1.0 0.5 0.1 0.3 0.1 0.0 14.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.4 0.0 1.6 0.0 0.1 0.0 FFAR1 "FFA1R, GPR40" ENSG00000126266 "Free fatty acid receptor 1" O14842 19 35351552-35353862 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 2.8;brain: 4.8;ovary: 2.5;pancreas: 4.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;granulocytes: 1.3;Granulosa cells: 1.4" "Cancer enriched" "Detected in single" 13 "pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-698: 1.6" "Not detected" "Not detected" HPA048933 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA048933: " "unprognostic (9.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" "unprognostic (4.46e-2)" "unprognostic (6.19e-2)" "unprognostic (9.56e-3)" 0.0 0.0 1.5 0.1 2.1 2.8 0.0 1.4 1.9 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.3 1.5 0.0 0.0 0.1 0.4 2.1 1.6 2.5 4.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.3 0.6 0.2 1.9 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 2.1 1.4 1.9 1.3 1.5 2.1 1.6 2.1 1.3 1.9 4.8 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.3 1.4 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;dendritic cells: 29.7;Kupffer cells: 118.2;Langerhans cells: 49.3;Macrophages: 52.0;Microglial cells: 43.1;monocytes: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;Daudi: 11.5;HDLM-2: 11.3;U-698: 9.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" 6.1 3.3 1.0 14.8 1.3 6.0 2.6 1.2 1.3 1.5 2.3 3.4 3.7 1.3 1.5 2.4 2.8 4.1 1.6 1.0 1.6 1.4 2.5 8.0 22.5 3.2 1.7 1.0 1.3 0.3 1.1 2.7 1.9 1.5 2.7 0.1 2.3 1.8 0.6 2.1 11.1 4.7 2.1 39.7 3.8 0.6 2.1 5.5 2.7 0.9 9.8 4.5 1.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 11.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 22.3 2.3 0.1 64.8 0.1 23.2 0.0 0.0 35.0 18.6 0.0 0.0 0.3 0.4 70.5 27.4 0.1 7.5 1.0 1.3 1.2 1.3 1.0 1.6 3.2 1.7 1.9 2.1 2.1 2.0 0.3 6.4 7.4 0.0 53.7 2.0 3.0 1.0 0.6 0.3 0.7 0.6 3.2 2.8 0.5 0.0 0.0 0.3 29.7 0.3 0.0 2.8 11.9 0.5 0.2 1.2 0.0 1.3 0.1 0.9 0.4 1.0 1.5 1.2 7.6 0.0 2.5 0.6 17.7 0.0 0.2 0.1 4.1 118.2 49.3 2.1 1.5 52.0 1.8 43.1 51.8 0.4 2.1 0.5 0.2 1.0 3.9 0.0 14.2 1.6 0.1 0.2 3.2 0.2 0.0 2.3 0.5 0.0 0.1 3.3 2.3 0.4 3.0 0.1 0.4 5.6 GGA2 "KIAA1080, VEAR" ENSG00000103365 "Golgi associated, gamma adaptin ear containing, ARF binding protein 2" Q9UJY4 16 23463542-23521995 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 159.9;U-698: 170.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034422, HPA043313, HPA063634" Approved Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "CAB034422: AB_2110748, HPA043313: AB_2678421, HPA063634: AB_2685067" "unprognostic (1.27e-1)" "prognostic favorable (1.71e-5)" "unprognostic (8.53e-2)" "unprognostic (2.22e-2)" "unprognostic (4.91e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.68e-1)" "prognostic favorable (1.68e-4)" "unprognostic (7.82e-3)" "unprognostic (3.88e-2)" "unprognostic (2.15e-3)" "unprognostic (8.55e-2)" "prognostic favorable (3.91e-5)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (3.89e-2)" "unprognostic (2.08e-1)" 15.1 36.3 13.0 32.0 13.1 37.6 19.9 18.6 14.8 20.7 25.2 16.5 10.0 16.1 19.6 17.9 18.4 13.4 18.5 13.8 15.3 26.9 16.4 34.1 72.9 11.7 12.9 34.0 54.3 29.2 26.0 17.6 11.9 27.4 15.8 79.3 37.6 21.3 25.5 21.1 33.6 14.9 10.8 44.2 25.7 12.4 17.8 37.2 36.2 19.0 87.3 16.3 18.7 12.3 18.8 22.9 29.6 26.1 16.5 17.9 25.3 19.7 20.0 15.2 19.3 32.1 18.9 159.9 31.4 21.1 4.3 28.7 49.1 25.8 19.4 25.1 45.6 28.8 29.5 51.2 16.2 48.0 18.2 18.7 22.7 20.8 9.7 22.1 22.0 12.8 50.3 23.0 19.8 29.8 17.0 31.9 39.6 18.3 20.2 108.3 38.4 41.2 24.8 25.6 21.1 25.3 18.3 27.0 27.1 31.5 23.7 59.7 24.5 18.1 19.6 20.3 18.5 42.0 41.8 170.8 16.5 32.2 20.6 0.2 4.2 7.0 3.1 4.3 3.2 16.2 3.9 3.7 4.9 21.6 4.0 4.0 0.5 3.1 4.0 15.9 4.5 3.1 13.0 13.1 18.6 14.8 13.8 15.3 11.7 12.9 11.9 10.8 17.8 12.3 11.7 48.1 41.4 28.7 102.3 34.2 33.6 16.5 39.3 73.2 25.0 26.0 27.3 21.5 17.6 22.0 114.7 23.0 80.6 7.3 25.4 19.3 22.0 25.4 17.6 19.0 17.6 9.9 44.2 18.9 40.7 17.3 15.3 37.3 9.5 88.5 12.5 16.1 69.1 6.7 61.5 12.6 12.2 26.1 19.7 30.8 24.5 37.7 26.6 36.5 87.9 23.8 23.7 26.2 8.3 16.2 6.1 26.4 36.1 20.7 8.7 21.5 16.2 153.3 19.7 16.0 16.3 30.5 60.5 25.4 14.6 22.7 34.8 56.8 11.9 18.6 GH1 "GH, GH-N, GHN, hGH-N" ENSG00000259384 "Growth hormone 1" P01241 17 63917200-63918839 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 868 "pituitary gland: 59365.3" "Cell type enhanced" "Detected in single" "Adipocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043715 Supported "Secreted to blood" NA NA 2690000 6400000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 57: B-cells - Immune response" "HPA043715: AB_2678632" "unprognostic (1.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-1)" "unprognostic (9.45e-4)" "unprognostic (2.48e-1)" "unprognostic (2.09e-4)" "unprognostic (2.03e-2)" "unprognostic (6.57e-2)" "unprognostic (2.33e-1)" 14.8 68.3 0.1 0.0 0.1 0.1 2.1 0.1 0.6 1.9 0.1 3.7 0.5 4.1 0.0 9.5 2.8 0.0 7.8 0.1 0.4 4.1 18.4 3.5 0.0 0.1 0.1 6.1 7.7 0.0 59365.3 0.8 0.1 5.5 0.0 0.0 4.8 0.0 3.5 36.2 3.9 0.0 0.1 7.7 11.8 7.2 0.1 0.3 5.4 0.1 0.0 1.5 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 GNG7 FLJ00058 ENSG00000176533 "G protein subunit gamma 7" O60262 19 2511219-2702694 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "brain: 360.9" "Cell type enhanced" "Detected in many" "B-cells: 145.4;Distal tubular cells: 123.3;Horizontal cells: 169.9;Oligodendrocyte precursor cells: 102.5;Oligodendrocytes: 206.1;Plasma cells: 169.7" "Cancer enhanced" "Detected in all" "glioma: 21.9;melanoma: 20.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 57.2;naive B-cell: 50.1;plasmacytoid DC: 48.0" "Group enriched" "Detected in many" 4 "B-cells: 57.2;dendritic cells: 48.0" "Cell line enhanced" "Detected in many" "Daudi: 22.3;REH: 66.5;SK-MEL-30: 31.2;U-266/70: 61.0;U-266/84: 30.0" "Region enriched" "Detected in all" 6 "basal ganglia: 1277.2" HPA057790 Supported Supported NA NA 72000 "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA057790: AB_2683527" "unprognostic (3.97e-3)" "unprognostic (1.16e-4)" "unprognostic (4.92e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-1)" "unprognostic (8.42e-4)" "prognostic favorable (3.05e-4)" "prognostic favorable (1.35e-5)" "unprognostic (1.27e-2)" "unprognostic (4.95e-2)" "prognostic favorable (3.71e-4)" "unprognostic (1.27e-1)" "prognostic favorable (0.00e+0)" "unprognostic (6.96e-2)" "unprognostic (1.46e-1)" "unprognostic (6.36e-2)" "unprognostic (4.96e-2)" 3.5 5.7 70.8 5.3 360.9 6.6 4.4 83.9 127.9 5.5 14.0 6.7 5.2 7.2 5.1 12.0 8.2 3.5 26.4 70.1 66.0 10.5 4.2 4.0 9.9 97.2 87.9 12.2 8.0 6.2 17.4 1.4 76.8 9.5 3.1 15.1 26.0 5.7 3.4 2.6 14.2 3.5 76.0 19.4 6.8 8.9 154.1 2.7 5.8 8.1 9.4 7.9 3.3 81.4 0.2 0.0 3.2 7.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.7 22.3 1.0 0.3 0.3 0.2 3.5 0.0 0.1 0.0 3.1 0.6 0.1 2.7 1.6 0.0 12.9 0.4 0.5 0.0 0.2 0.2 0.0 2.7 0.3 14.2 0.0 2.2 0.6 1.4 2.6 0.4 1.4 66.5 0.0 6.2 0.3 0.0 0.1 9.2 0.1 0.1 31.2 2.1 0.4 5.6 0.1 0.1 3.0 0.2 0.2 61.0 30.0 4.7 0.2 7.0 16.5 3.5 1.5 8.0 0.4 0.5 1.1 57.2 0.5 0.4 6.0 50.1 1.2 0.7 11.8 0.2 0.1 48.0 0.0 3.0 70.8 360.9 83.9 127.9 70.1 66.0 97.2 87.9 76.8 76.0 154.1 81.4 14.5 6.4 4.2 40.8 145.4 2.5 13.0 0.3 5.2 10.5 22.9 30.1 55.1 15.7 3.3 9.2 8.4 0.6 56.1 0.9 123.3 17.0 5.4 2.1 2.3 11.7 6.1 8.6 26.5 4.8 1.1 6.6 5.6 3.5 12.7 8.6 19.2 11.4 63.2 169.9 38.8 2.0 0.0 8.5 15.0 11.4 2.5 12.3 51.6 45.9 11.2 84.7 3.1 102.5 206.1 2.7 1.8 2.6 169.7 7.5 0.7 22.6 2.9 11.1 6.6 7.1 5.4 2.7 2.6 1.5 2.0 3.4 6.9 2.1 2.2 7.2 GRB2 NCKAP2 ENSG00000177885 "Growth factor receptor bound protein 2" P62993 17 75318076-75405709 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 340.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002589, HPA030749, HPA030750" Approved Supported Nucleoplasm,Nucleoli NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Nucleoli "CAB002589: AB_10693935, HPA030749: AB_2673590, HPA030750: AB_2673591" "unprognostic (4.83e-3)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (3.42e-3)" "unprognostic (1.70e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.04e-7)" "unprognostic (1.01e-2)" "unprognostic (2.73e-1)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-2)" "unprognostic (1.08e-2)" "unprognostic (8.13e-2)" "unprognostic (3.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.58e-1)" 55.7 58.0 66.1 98.3 64.8 127.1 40.3 56.6 66.1 35.9 49.9 54.7 57.3 46.4 31.5 51.0 39.5 43.2 53.3 71.0 68.7 50.5 54.0 65.5 116.9 64.1 64.8 39.3 35.0 39.8 42.6 64.5 61.5 41.8 52.6 24.1 40.6 45.8 48.8 36.3 60.6 58.9 67.5 92.2 44.6 18.5 68.5 83.1 37.6 39.1 107.3 67.5 36.1 72.3 98.6 87.7 58.9 71.1 64.1 54.5 129.5 91.2 70.5 89.3 87.3 75.8 66.7 128.9 57.9 97.0 77.5 58.5 84.0 76.1 89.8 63.4 76.5 137.2 55.7 111.8 57.3 162.8 259.0 55.2 78.0 112.9 55.8 62.3 128.3 125.3 95.5 88.8 64.9 127.4 160.3 160.5 40.5 98.9 81.3 113.7 123.8 94.9 82.7 75.0 66.6 101.1 83.7 85.4 114.7 102.8 94.4 264.9 83.4 100.0 71.0 81.8 104.9 161.1 127.3 205.5 79.1 125.8 75.3 134.5 136.1 164.9 52.3 160.9 45.0 94.5 48.0 52.2 101.2 96.5 46.8 47.8 273.8 51.5 185.1 71.9 56.5 102.9 66.1 64.8 56.6 66.1 71.0 68.7 64.1 64.8 61.5 67.5 68.5 72.3 73.5 60.9 62.2 18.3 210.5 47.0 45.7 31.0 67.7 35.7 45.6 37.5 59.7 41.5 46.9 16.5 31.3 71.9 137.6 74.4 52.8 64.8 3.0 52.9 56.4 60.9 41.9 55.5 41.5 63.4 340.9 47.2 47.9 57.6 124.4 30.0 41.7 42.3 260.3 35.3 41.1 46.4 22.4 182.0 243.8 5.6 25.1 259.9 46.2 81.5 237.0 47.1 73.2 31.7 41.5 77.2 69.6 41.8 236.3 63.3 60.1 69.9 55.1 46.4 6.6 34.6 50.5 27.4 49.9 76.3 44.8 87.2 109.0 59.7 44.9 92.7 HLA-DOB ENSG00000241106 "Major histocompatibility complex, class II, DO beta" P13765 6 32812763-32820466 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 19.5;lymphoid tissue: 41.0" "Cell type enhanced" "Detected in many" "B-cells: 84.4;Langerhans cells: 35.6;monocytes: 44.7;Plasma cells: 35.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "memory B-cell: 213.8;naive B-cell: 258.1" "Lineage enriched" "Detected in many" 20 "B-cells: 258.1" "Cell line enhanced" "Detected in some" "Daudi: 38.1;U-698: 14.9;U-937: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013846 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA013846: AB_1853928" "prognostic favorable (4.29e-4)" "unprognostic (3.84e-2)" "unprognostic (7.12e-3)" "unprognostic (6.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.00e-2)" "unprognostic (4.48e-2)" "unprognostic (4.26e-3)" "unprognostic (6.95e-2)" "prognostic favorable (4.17e-5)" "unprognostic (2.37e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.15e-5)" "unprognostic (1.37e-1)" "unprognostic (1.64e-1)" "unprognostic (7.18e-2)" "unprognostic (2.46e-1)" 1.0 0.6 0.1 0.8 0.2 3.3 1.5 0.1 0.5 0.9 0.0 2.7 1.9 0.7 0.0 2.0 0.7 1.2 0.5 0.1 0.2 2.1 0.9 2.9 21.6 0.3 0.1 0.6 0.3 0.0 2.7 0.0 0.2 1.1 1.9 1.1 4.2 0.8 0.2 1.7 19.5 0.4 0.2 41.0 2.0 1.2 0.2 8.3 1.9 1.3 28.2 3.7 1.3 0.2 0.2 0.0 0.0 0.1 0.4 1.3 0.1 0.1 0.0 0.0 0.8 0.4 2.2 38.1 0.3 0.5 0.0 0.5 2.6 2.3 0.0 1.0 0.6 0.1 1.1 0.0 0.0 0.1 0.3 0.6 0.7 0.0 1.0 0.0 0.0 0.4 2.0 1.4 0.0 0.0 0.3 2.4 0.0 0.0 0.0 0.7 0.2 2.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 1.1 0.2 0.0 0.0 0.3 0.9 0.5 14.9 0.0 7.0 0.0 0.1 0.2 0.1 0.1 0.0 0.1 213.8 0.3 0.1 13.2 258.1 0.0 0.2 0.5 0.2 0.3 0.6 0.8 6.8 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.1 0.2 0.2 0.2 0.2 1.7 0.0 4.8 5.9 84.4 1.0 0.3 2.2 1.2 0.9 1.2 0.9 0.0 0.0 1.0 0.0 0.0 0.0 4.7 0.1 0.0 0.9 1.3 4.3 2.4 0.9 0.0 2.7 1.0 0.2 0.4 0.3 0.0 14.8 1.3 0.2 0.0 0.0 0.6 0.0 1.8 0.1 0.0 1.0 35.6 0.9 0.0 4.6 14.2 1.9 44.7 0.7 2.1 2.0 1.3 0.4 0.0 0.0 35.0 0.3 0.4 0.3 0.4 0.6 6.6 0.4 1.2 0.1 0.3 0.7 1.6 0.0 2.3 0.1 0.3 0.4 HPS3 "BLOC2S1, SUTAL" ENSG00000163755 "HPS3 biogenesis of lysosomal organelles complex 2 subunit 1" Q969F9 3 149129638-149173732 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 115.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046281, HPA052778" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" "HPA046281: AB_10961641, HPA052778: AB_2681943" "unprognostic (1.47e-2)" "unprognostic (7.83e-2)" "unprognostic (1.04e-1)" "unprognostic (1.11e-3)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (6.04e-4)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.82e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (2.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.03e-1)" "unprognostic (3.06e-2)" 7.6 9.2 4.2 11.4 4.7 5.6 7.9 4.8 4.2 7.5 8.3 7.5 11.0 9.9 4.9 5.6 8.6 9.0 5.0 3.7 6.0 12.0 8.0 9.7 17.6 6.7 5.6 14.0 6.7 5.7 3.7 10.6 6.8 9.3 9.1 9.6 6.6 8.5 2.8 4.7 10.8 10.3 5.6 16.0 9.2 6.9 5.2 16.8 8.8 3.9 16.4 8.4 5.2 8.5 49.1 26.5 15.7 16.3 21.4 27.4 11.7 19.7 38.4 25.3 32.4 9.1 31.8 12.4 23.8 23.7 115.3 16.5 17.4 13.4 32.4 30.6 13.9 5.8 11.8 9.9 19.1 15.7 9.1 18.0 13.5 24.4 10.0 51.6 26.2 20.2 6.5 29.4 32.5 30.3 11.3 22.1 37.7 26.3 21.1 13.4 10.3 33.7 13.9 24.1 4.7 12.4 16.8 17.7 35.9 33.4 19.2 20.5 13.2 25.2 4.5 26.0 29.0 24.0 10.0 30.6 37.7 30.1 6.3 20.7 12.5 12.1 12.0 15.2 14.5 15.4 10.9 12.9 19.5 12.2 8.4 10.9 5.7 9.8 10.3 11.0 10.7 10.9 4.2 4.7 4.8 4.2 3.7 6.0 6.7 5.6 6.8 5.6 5.2 8.5 9.9 12.8 19.5 17.6 28.6 3.7 3.9 11.5 6.8 6.7 9.1 7.4 2.5 5.7 22.9 7.3 2.1 21.0 24.3 8.0 5.9 10.7 3.0 10.6 11.6 9.9 9.0 7.4 13.3 18.1 14.6 10.8 16.8 10.4 15.2 18.0 17.5 6.9 19.8 3.3 16.5 8.8 14.2 29.3 23.8 4.8 11.5 33.1 14.2 38.4 14.4 25.1 19.6 19.1 27.3 12.9 4.9 30.1 15.4 6.8 13.6 22.8 20.7 5.2 0.0 7.4 8.4 4.4 8.4 8.7 5.3 14.1 18.9 5.4 7.5 5.1 HVCN1 "Hv1, MGC15619, VSOP" ENSG00000122986 "Hydrogen voltage gated channel 1" Q96D96 12 110627841-110704950 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 162.1;lymphoid tissue: 72.9" "Cell type enhanced" "Detected in many" "B-cells: 178.4;Early spermatids: 87.3;Hofbauer cells: 57.0;Late spermatids: 76.4;Spermatocytes: 117.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "NB-4: 286.4;U-698: 90.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039329 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "HPA039329: AB_10674284" "unprognostic (3.43e-2)" "unprognostic (6.32e-3)" "unprognostic (7.05e-2)" "unprognostic (1.54e-2)" "unprognostic (4.62e-3)" "unprognostic (3.89e-2)" "unprognostic (1.96e-1)" "unprognostic (5.85e-3)" "unprognostic (2.40e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-2)" "unprognostic (5.67e-2)" "unprognostic (3.35e-3)" "unprognostic (4.82e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" 8.2 5.1 23.4 32.0 34.7 6.9 5.2 24.3 21.1 9.3 162.1 6.5 4.8 10.1 11.5 4.6 9.2 8.3 17.5 26.2 29.5 3.3 4.4 13.7 65.0 25.7 32.8 13.5 1.7 2.2 3.0 8.1 27.8 6.4 6.7 2.7 3.9 8.7 7.9 3.0 17.8 10.3 20.2 42.7 7.6 44.7 27.6 16.2 3.9 9.8 72.9 9.7 5.2 25.0 0.1 0.5 2.8 0.2 4.5 4.7 1.4 0.9 1.1 2.6 1.4 0.5 0.0 2.9 2.4 5.1 0.0 0.4 3.3 0.2 3.7 0.2 0.6 0.1 0.3 0.7 4.0 44.1 3.1 6.2 0.4 2.4 0.0 0.4 6.4 13.4 1.9 2.4 4.7 0.2 6.4 286.4 3.2 0.0 2.7 5.4 0.2 0.3 0.0 0.1 0.3 0.4 0.1 0.0 0.2 2.9 0.0 42.8 1.9 0.0 0.2 0.4 0.1 27.4 3.7 90.5 0.3 2.2 0.2 378.0 208.3 675.7 14.0 197.8 7.7 550.4 13.2 22.7 88.7 799.8 25.2 17.2 327.4 182.6 185.0 131.7 31.0 193.2 23.4 34.7 24.3 21.1 26.2 29.5 25.7 32.8 27.8 20.2 27.6 25.0 18.4 3.2 5.3 9.4 178.4 0.8 1.9 2.0 1.2 0.5 1.2 2.8 6.6 0.0 3.6 1.8 0.0 0.4 25.8 0.0 0.0 0.5 87.3 0.5 5.8 13.1 0.0 0.8 0.6 0.2 1.4 5.4 1.5 0.3 8.2 3.9 12.1 0.3 57.0 0.0 0.5 0.2 0.0 41.7 17.2 76.4 13.4 42.2 12.4 15.0 31.6 15.2 23.7 2.0 0.1 0.5 0.1 13.9 9.9 0.6 0.0 0.5 1.7 1.8 13.1 4.7 15.1 117.5 2.8 0.7 0.4 1.2 7.6 0.5 0.2 1.2 IFNA6 IFN-alphaK ENSG00000120235 "Interferon alpha 6" P05013 9 21349835-21351378 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "Cluster 57: B-cells - Immune response" "HPA047557: AB_2680087" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "urinary bladder: 204.7" "Group enriched" "Detected in some" 17 "B-cells: 2.4;Plasma cells: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.7" "Lineage enriched" "Detected in single" 58 "B-cells: 12.7" "Cell line enhanced" "Detected in single" "MOLT-4: 1.5" "Immunoglobulin genes" NA NA 120000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (9.63e-3)" "unprognostic (6.78e-2)" "unprognostic (5.64e-2)" "unprognostic (4.04e-2)" "prognostic favorable (7.25e-4)" "unprognostic (4.56e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-1)" "unprognostic (1.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "unprognostic (6.79e-2)" "unprognostic (1.36e-1)" 8.1 3.4 0.0 13.8 0.0 5.9 3.8 0.0 0.0 0.8 0.0 19.5 15.7 0.4 0.0 8.3 1.1 4.7 1.0 0.0 0.0 1.5 1.4 5.4 41.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 27.8 0.0 23.5 1.9 0.0 0.2 9.8 0.1 0.0 26.2 13.1 0.5 0.0 10.3 1.1 0.0 51.1 204.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 128.8;lymphoid tissue: 98.5;urinary bladder: 227.1" "Group enriched" "Detected in some" 39 "B-cells: 8.3;Plasma cells: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 13.9" "Lineage enriched" "Detected in single" 140 "B-cells: 13.9" "Cell line enhanced" "Detected in some" "HL-60: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 190000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 57: B-cells - Immune response" "unprognostic (9.39e-3)" "unprognostic (4.50e-2)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (4.99e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "unprognostic (2.24e-1)" "unprognostic (8.09e-2)" 6.2 7.7 0.0 59.0 0.0 21.6 14.0 0.0 0.3 15.5 0.2 35.0 61.5 4.2 0.0 31.5 3.8 128.8 5.6 0.0 0.4 2.3 6.0 20.7 3.5 0.2 0.6 0.5 1.6 0.0 0.3 0.0 0.1 6.3 86.5 0.0 44.2 0.9 0.1 0.5 55.1 4.4 0.2 98.5 65.1 0.0 1.1 0.0 6.8 0.0 21.8 227.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.2 1.1 0.2 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.5;lymphoid tissue: 137.3;urinary bladder: 90.5" "Group enriched" "Detected in some" 6 "B-cells: 6.7;Plasma cells: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 193 "memory B-cell: 18.8;naive B-cell: 19.6" "Lineage enriched" "Detected in single" 197 "B-cells: 19.6" "Cell line enhanced" "Detected in some" "MOLT-4: 1.8;U-266/70: 1.0" "Immunoglobulin genes" NA NA 33000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (3.24e-4)" "unprognostic (7.42e-2)" "unprognostic (1.96e-2)" "unprognostic (5.03e-2)" "prognostic favorable (6.67e-6)" "unprognostic (5.44e-2)" "unprognostic (1.23e-2)" "unprognostic (1.53e-1)" "unprognostic (5.31e-2)" "unprognostic (8.27e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.21e-5)" "unprognostic (6.79e-2)" "unprognostic (3.21e-1)" "unprognostic (4.45e-1)" "unprognostic (7.87e-2)" 1.3 36.6 0.0 24.1 0.0 6.9 17.2 0.0 0.1 1.9 0.0 67.5 49.5 1.5 0.0 15.4 4.3 9.7 1.8 0.0 0.0 1.1 1.5 7.2 39.5 0.0 0.1 1.5 0.7 0.0 0.1 0.0 0.0 1.1 36.1 0.0 30.9 1.4 0.0 0.1 22.8 5.6 0.1 56.5 42.9 0.9 0.0 9.3 2.8 0.0 137.3 90.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Cholangiocytes: 1.5;Erythroid cells: 5.3;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cell line enhanced" "Detected in some" "Daudi: 1.4;HEL: 1.1;HL-60: 1.1;K-562: 1.7" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" 4.4 13.3 0.0 9.4 0.0 15.8 10.5 0.0 0.5 4.7 0.3 76.9 141.8 5.1 0.0 4.0 3.9 19.1 10.4 0.0 0.0 3.0 9.8 12.3 0.0 0.1 0.0 1.5 5.9 0.0 0.5 0.1 0.2 4.3 58.0 0.0 30.6 3.9 0.4 0.2 23.6 0.4 0.1 83.0 47.5 0.4 0.0 0.0 4.1 0.0 0.2 81.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 69.9 0.1 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 IGHV7-81 ENSG00000211979 "Immunoglobulin heavy variable 7-81 (non-functional)" A0A0B4J1V7 14 106874583-106875071 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;lymphoid tissue: 18.3;stomach 1: 12.3" "Group enriched" "Detected in some" 12 "B-cells: 1.5;Plasma cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 5.5;naive B-cell: 3.9" "Lineage enriched" "Detected in single" 14 "B-cells: 5.5" "Cell line enhanced" "Detected in some" "A549: 1.1;Daudi: 6.1;OE19: 1.2;U-698: 2.0" "Immunoglobulin genes" NA NA 270000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (5.71e-4)" "unprognostic (3.87e-1)" "unprognostic (1.06e-1)" "unprognostic (6.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.24e-1)" "unprognostic (2.07e-1)" "unprognostic (1.14e-2)" "unprognostic (6.16e-5)" "unprognostic (1.69e-3)" "unprognostic (1.78e-2)" "unprognostic (1.08e-1)" "unprognostic (5.63e-2)" "unprognostic (3.44e-1)" "unprognostic (3.63e-2)" 0.1 0.1 0.0 8.4 0.0 4.6 3.6 0.0 0.0 0.3 0.0 7.6 6.4 0.4 0.0 0.6 0.3 7.9 0.2 0.0 0.0 0.3 0.2 1.8 4.2 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 2.3 12.7 0.0 5.0 0.1 0.0 0.2 6.2 0.4 0.0 2.3 12.3 0.1 0.0 1.4 0.0 0.0 18.3 1.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.5 0.3 0.1 0.0 3.9 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Cell type enriched" "Detected in single" 13 "B-cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Cell line enriched" "Detected in some" 24 "U-698: 3392.4" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" 25.2 42.2 0.5 1365.8 0.7 164.5 236.5 0.6 4.5 73.7 0.3 1194.4 1221.3 13.4 5.8 130.7 8.8 78.5 26.1 0.9 0.7 18.0 30.8 157.6 529.7 1.6 0.6 63.3 29.2 6.6 0.0 4.1 1.2 22.8 1171.9 0.0 643.7 17.1 0.0 5.8 1078.7 40.6 4.9 672.7 1066.6 12.4 0.7 61.5 4.3 0.0 1213.5 436.6 0.0 0.9 17.7 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 142.3 0.0 0.0 0.0 0.0 0.0 7.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 58.5 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.3 3.5 11.4 3.2 1.9 3392.4 0.0 8.1 0.0 3.3 10.1 10.2 3.8 1.3 2.2 9254.1 18.4 3.5 7.4 8737.5 9.5 3.4 9.4 7.6 3.4 373.6 8.8 1167.3 0.5 0.7 0.6 4.5 0.9 0.7 1.6 0.6 1.2 4.9 0.7 0.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-26 ENSG00000211623 "Immunoglobulin kappa variable 2D-26" A0A0A0MRZ7 2 89985922-89986702 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 245 "memory B-cell: 21.8;naive B-cell: 27.1" "Lineage enriched" "Detected in single" 272 "B-cells: 27.1" "Cell line enriched" "Detected in single" 10 "U-698: 1.0" "Immunoglobulin genes" NA NA 1000000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.11e-1)" "unprognostic (6.09e-2)" 0.0 0.4 0.0 1.5 0.1 0.5 1.0 0.0 0.2 0.1 0.0 4.6 3.5 0.0 0.0 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 0.0 0.0 2.8 0.0 0.0 2.3 1.3 0.0 0.0 0.5 0.0 0.0 6.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.2;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.7;NK-cell: 5.6" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.6;T-cells: 4.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" 0.8 1.2 0.0 3.9 0.0 2.7 1.9 0.0 0.3 0.3 0.1 7.3 5.5 0.5 0.0 1.0 0.6 3.3 0.0 0.0 0.0 0.1 0.5 2.7 15.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 5.1 1.7 0.0 0.2 2.7 0.1 0.0 4.6 8.2 0.9 0.0 3.9 0.2 0.0 30.1 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 1.1 9.2 1.0 4.0 0.0 6.7 0.0 0.2 0.0 5.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 80.3;urinary bladder: 42.9" "Group enriched" "Detected in some" 49 "B-cells: 6.2;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 393 "memory B-cell: 107.2;naive B-cell: 121.2" "Lineage enriched" "Detected in single" 417 "B-cells: 121.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 350000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" 1.5 0.0 0.0 6.9 0.0 6.3 4.9 0.0 0.0 0.7 0.0 10.7 9.9 0.2 0.0 2.5 1.9 1.2 0.6 0.0 0.0 0.7 1.3 4.7 13.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.6 10.8 0.0 10.8 0.0 0.0 0.1 5.2 0.6 0.0 12.8 13.0 0.3 0.0 3.5 0.2 0.0 80.3 42.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 107.2 0.0 0.1 0.1 121.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV5-37 ENSG00000211654 "Immunoglobulin lambda variable 5-37" A0A075B6J1 22 22427540-22428035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 24.7;intestine: 10.5;lymphoid tissue: 41.5;salivary gland: 11.5;stomach 1: 16.5" "Group enriched" "Detected in some" 4 "B-cells: 2.5;Late spermatids: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "memory B-cell: 6.1;naive B-cell: 7.0" "Lineage enriched" "Detected in single" 58 "B-cells: 7.0" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 14000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (4.69e-4)" "unprognostic (2.44e-2)" "unprognostic (5.68e-3)" "unprognostic (4.26e-1)" "prognostic favorable (4.71e-4)" "unprognostic (4.97e-2)" "unprognostic (3.56e-2)" "unprognostic (3.15e-1)" "unprognostic (5.34e-6)" "unprognostic (1.66e-1)" "unprognostic (4.32e-1)" "unprognostic (1.25e-1)" 0.7 0.0 0.0 9.5 0.0 1.0 3.2 0.0 0.0 1.8 0.0 10.5 10.1 0.2 0.0 4.2 0.9 24.7 1.1 0.0 0.0 0.9 0.7 3.6 4.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.6 8.0 0.1 11.5 0.0 0.0 0.0 8.8 0.2 0.0 22.7 16.5 1.2 0.0 8.4 0.6 0.0 41.5 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV5-52 ENSG00000211643 "Immunoglobulin lambda variable 5-52" A0A0A0MRZ9 22 22318727-22319226 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "B-cells: 1.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 11.7;naive B-cell: 10.3" "Lineage enriched" "Detected in many" 6 "B-cells: 11.7" "Low cell line specificity" "Detected in all" "Immunoglobulin genes" NA NA 1200000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "unprognostic (7.26e-2)" "unprognostic (7.05e-2)" "unprognostic (1.86e-2)" "unprognostic (4.66e-1)" "unprognostic (1.29e-1)" "unprognostic (7.61e-5)" "unprognostic (1.22e-1)" "unprognostic (1.89e-1)" "unprognostic (8.45e-2)" "unprognostic (1.51e-1)" "unprognostic (3.93e-2)" "unprognostic (2.25e-3)" "unprognostic (7.75e-2)" "unprognostic (3.51e-2)" "unprognostic (1.57e-1)" "unprognostic (5.46e-2)" 11.5 10.4 10.7 18.0 11.7 14.6 23.8 16.4 14.1 16.5 13.2 26.6 20.1 28.4 44.2 22.5 22.7 22.5 16.6 11.9 11.1 11.5 9.5 14.9 44.1 9.4 9.4 21.6 8.0 13.9 8.6 11.2 11.0 15.9 23.5 22.5 17.9 15.0 10.1 37.7 15.3 22.3 9.2 21.8 29.2 12.9 10.8 17.7 21.4 15.6 53.5 31.1 6.3 13.9 12.1 7.7 18.8 29.2 22.3 25.1 14.4 7.7 19.0 17.3 22.0 15.6 5.0 38.4 8.5 22.5 10.1 16.9 36.0 25.6 24.0 9.4 27.3 13.4 21.4 14.8 8.7 20.8 22.9 24.0 24.0 19.5 34.5 14.2 35.2 13.9 40.7 3.3 32.3 14.5 7.0 13.9 10.5 22.5 5.7 9.4 9.4 6.4 22.6 16.1 21.2 13.2 9.9 10.6 10.9 15.7 21.0 4.8 21.0 40.9 25.7 4.2 9.0 6.7 21.9 18.2 14.0 15.4 12.2 0.0 1.3 1.9 1.1 0.7 1.3 11.7 1.2 1.3 1.5 10.3 0.8 0.8 0.7 0.7 0.8 1.4 0.6 3.1 10.7 11.7 16.4 14.1 11.9 11.1 9.4 9.4 11.0 9.2 10.8 13.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 KMO ENSG00000117009 "Kynurenine 3-monooxygenase" O15229 1 241532134-241595642 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Pyridine nucleotide biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 31.5;liver: 91.7" "Cell type enhanced" "Detected in many" "B-cells: 33.8;Hepatocytes: 46.9;Langerhans cells: 49.4;Macrophages: 33.0;Proximal tubular cells: 63.2;Syncytiotrophoblasts: 180.1" "Group enriched" "Detected in many" 4 "breast cancer: 1.6;liver cancer: 3.3;renal cancer: 3.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 79 "classical monocyte: 11.0;intermediate monocyte: 32.3;memory B-cell: 36.1;myeloid DC: 11.3;naive B-cell: 42.0;non-classical monocyte: 33.8;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 97 "B-cells: 42.0;dendritic cells: 24.3;monocytes: 33.8" "Cell line enhanced" "Detected in some" "Daudi: 6.2;RPMI-8226: 9.1;RPTEC TERT1: 21.9;SK-BR-3: 10.9;U-698: 9.4" "Region enriched" "Detected in single" 4 "thalamus: 1.1" "Low region specificity" "Detected in many" "HPA031115, HPA056942" Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 57: B-cells - Immune response" "HPA031115: AB_10601924, HPA056942: AB_2683281" "unprognostic (4.27e-2)" "unprognostic (3.35e-2)" "unprognostic (3.95e-2)" "unprognostic (7.48e-3)" "unprognostic (8.37e-3)" "unprognostic (2.63e-1)" "unprognostic (9.79e-2)" "unprognostic (3.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.75e-3)" "unprognostic (8.07e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (6.49e-8)" "unprognostic (1.60e-2)" "unprognostic (3.65e-2)" "unprognostic (3.36e-2)" "unprognostic (6.81e-2)" 1.4 0.8 0.1 5.1 0.2 1.4 5.3 0.1 1.0 0.6 0.5 0.9 0.6 5.4 0.2 0.2 0.2 1.6 0.4 0.3 0.0 31.5 91.7 5.0 8.8 0.0 0.0 0.2 0.1 0.1 0.2 6.8 0.1 0.3 1.1 0.2 0.3 0.2 0.1 0.2 1.2 0.7 0.0 8.4 1.2 1.3 0.8 1.6 0.2 0.0 11.2 5.6 0.1 0.3 0.2 1.8 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.2 0.4 0.0 0.2 6.2 0.4 0.0 0.2 2.5 0.0 0.2 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.6 0.2 0.2 0.7 0.1 0.2 0.5 0.0 0.4 0.1 0.9 0.0 0.2 0.0 2.4 1.0 0.9 0.4 1.6 0.1 9.1 21.9 4.5 0.3 0.1 0.0 10.9 0.1 2.1 4.3 2.1 0.0 0.0 0.1 0.1 1.6 0.4 0.6 9.4 0.2 2.7 1.8 0.1 11.0 0.2 0.0 32.3 0.0 36.1 0.0 0.0 11.3 42.0 0.0 0.1 0.3 0.0 33.8 24.3 0.0 6.1 0.1 0.2 0.1 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.1 0.0 0.5 0.0 33.8 1.0 0.1 13.3 2.2 0.0 1.8 0.8 0.4 2.8 11.1 0.0 0.0 3.6 5.5 0.1 5.9 4.8 4.9 9.5 1.5 0.3 0.0 5.2 6.6 0.2 2.3 0.4 2.0 26.6 0.0 0.1 0.7 46.9 7.0 0.0 30.0 0.0 4.1 22.7 49.4 1.8 0.0 33.0 0.0 0.0 5.5 0.0 1.0 1.0 0.6 1.5 0.0 0.0 11.7 0.2 0.2 63.2 2.3 0.0 0.0 0.1 1.3 1.6 0.3 3.1 1.4 180.1 1.6 0.1 0.0 0.1 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.6;granulocytes: 171.6;Hofbauer cells: 82.7;Kupffer cells: 71.1;Langerhans cells: 81.9;Macrophages: 89.1;monocytes: 89.6;NK-cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 192.2;REH: 205.7;RPMI-8226: 73.3;THP-1: 186.5;U-937: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" 6.8 5.4 9.7 37.7 11.1 61.3 3.8 11.8 12.8 3.7 9.1 6.5 6.3 2.9 2.5 3.6 4.2 9.1 2.3 10.3 12.2 3.3 4.8 19.2 51.6 18.4 13.6 1.7 3.0 2.2 3.0 7.4 17.7 7.1 7.7 1.2 4.5 3.5 3.3 3.0 13.6 8.8 16.5 47.0 6.5 2.0 15.3 12.2 2.8 2.4 56.6 10.1 2.5 20.1 1.7 1.1 1.1 3.1 0.3 0.0 1.1 1.4 1.2 0.6 0.7 2.3 28.9 19.6 0.4 0.5 6.1 1.2 0.4 1.1 0.6 31.4 1.2 8.6 1.8 1.8 0.1 56.1 55.6 0.4 0.8 2.1 0.6 1.2 0.3 1.1 1.6 9.3 0.5 1.7 1.3 192.2 0.9 5.5 2.0 205.7 1.1 73.3 0.2 1.7 0.9 0.8 0.6 1.2 1.2 0.9 1.1 186.5 2.1 2.1 19.9 0.8 1.8 0.9 6.2 32.2 9.4 177.6 1.5 871.6 276.6 46.0 8.8 159.0 0.9 169.3 2.3 1.4 225.2 191.1 1.0 2.9 491.0 73.9 93.9 8.9 4.9 214.7 9.7 11.1 11.8 12.8 10.3 12.2 18.4 13.6 17.7 16.5 15.3 20.1 1.3 3.2 16.2 0.7 90.6 3.4 0.7 0.0 0.6 0.3 1.0 1.9 1.1 5.7 3.1 3.7 0.0 0.6 47.8 0.2 0.0 0.3 2.4 1.3 0.6 3.9 7.8 16.6 1.7 0.2 1.1 1.7 1.1 2.1 171.6 0.4 3.9 4.5 82.7 0.0 1.4 0.8 0.0 71.1 81.9 3.4 0.0 89.1 1.8 20.6 89.6 0.2 70.0 0.5 0.9 0.6 0.1 0.7 18.7 1.2 0.1 0.2 5.9 1.3 0.0 1.9 0.9 0.4 1.4 0.1 2.6 1.2 27.7 0.3 0.8 0.4 LCN10 ENSG00000187922 "Lipocalin 10" Q6JVE6 9 136738167-136743356 "Predicted secreted proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 32.3" "Cell type enriched" "Detected in single" 32 "B-cells: 6.4" "Cancer enriched" "Detected in single" 8 "thyroid cancer: 1.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "memory B-cell: 6.5;naive B-cell: 6.4" "Lineage enriched" "Detected in single" 18 "B-cells: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055919 Approved "Secreted in male reproductive system" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 57: B-cells - Immune response" "HPA055919: AB_2682969" "unprognostic (2.02e-1)" "unprognostic (1.35e-2)" "unprognostic (2.62e-1)" "unprognostic (1.89e-1)" "unprognostic (5.85e-2)" "unprognostic (6.54e-3)" "unprognostic (2.22e-4)" "unprognostic (4.54e-2)" "unprognostic (3.97e-1)" "unprognostic (1.31e-1)" "unprognostic (4.14e-3)" "unprognostic (2.96e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (2.52e-1)" "unprognostic (8.32e-2)" "unprognostic (3.86e-1)" 3.5 0.1 1.4 1.0 1.3 0.8 2.8 1.2 2.3 6.1 1.2 1.7 0.1 7.7 32.3 1.2 7.8 0.4 8.2 1.3 1.2 0.1 0.1 0.9 1.3 1.3 1.3 2.1 1.0 0.3 0.1 0.0 1.3 2.7 0.7 0.0 1.6 1.0 0.8 0.7 2.7 3.1 1.2 1.6 2.2 1.2 1.6 0.3 2.1 2.0 1.1 3.2 2.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.4 1.3 1.2 2.3 1.3 1.2 1.3 1.3 1.3 1.2 1.6 1.3 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 LCN8 LCN5 ENSG00000204001 "Lipocalin 8" Q6JVE9 9 136754386-136758543 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 99 "epididymis: 83.7" "Group enriched" "Detected in some" 11 "B-cells: 17.9;Plasma cells: 5.6" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 60 "memory B-cell: 4.1;naive B-cell: 8.1" "Lineage enriched" "Detected in single" 79 "B-cells: 8.1" "Cell line enriched" "Detected in single" 6 "REH: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (6.71e-2)" "unprognostic (2.11e-2)" "unprognostic (2.92e-1)" "unprognostic (2.89e-1)" "unprognostic (2.00e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LRIF1 "C1orf103, FLJ11269, RIF1" ENSG00000121931 "Ligand dependent nuclear receptor interacting factor 1" Q5T3J3 1 110947190-110963965 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044515 Uncertain Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Centriolar satellite" "HPA044515: AB_10796800" "unprognostic (5.06e-2)" "unprognostic (4.82e-2)" "unprognostic (4.74e-1)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-3)" "unprognostic (1.85e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.73e-4)" "unprognostic (5.14e-2)" "unprognostic (9.23e-3)" "unprognostic (3.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.48e-1)" "unprognostic (3.88e-2)" "unprognostic (2.70e-1)" 6.6 9.4 8.7 10.3 9.1 5.5 11.4 10.7 18.5 6.2 8.5 6.5 6.0 6.8 19.8 5.6 8.1 5.0 14.5 9.2 10.3 7.9 13.2 6.8 16.0 8.4 8.7 15.5 6.1 6.5 7.7 10.0 8.7 8.2 6.4 21.5 7.2 5.4 18.2 9.3 6.0 4.7 8.7 13.0 7.1 25.7 9.5 13.3 10.9 17.3 17.4 7.6 4.5 10.0 33.2 14.4 26.8 18.4 12.3 19.8 30.2 19.9 22.7 33.8 27.2 36.4 40.4 25.2 27.5 15.1 36.5 21.0 12.9 12.0 40.6 45.9 15.2 27.9 14.3 37.4 35.8 52.7 32.5 12.5 32.3 23.5 41.0 14.4 18.6 26.4 88.3 111.5 23.2 11.1 5.4 41.4 40.0 20.1 32.6 35.0 43.4 30.5 8.8 17.0 22.3 24.4 0.1 33.8 59.1 16.3 28.0 83.6 13.5 30.0 1.0 35.4 16.3 51.7 19.4 46.9 17.1 59.2 53.6 24.8 8.3 18.6 21.0 9.4 26.6 29.9 16.6 22.1 16.8 22.7 18.1 24.8 31.4 28.2 13.0 15.0 16.9 12.8 8.7 9.1 10.7 18.5 9.2 10.3 8.4 8.7 8.7 8.7 9.5 10.0 22.5 12.8 8.4 11.8 39.4 14.4 48.4 21.0 19.9 22.4 27.9 35.1 27.8 8.6 17.0 9.2 18.8 19.5 21.9 15.5 15.6 18.8 15.3 15.9 15.2 21.5 11.3 24.8 17.9 19.9 32.3 16.5 23.0 18.5 8.2 11.2 17.5 31.8 13.9 15.2 16.5 13.2 18.3 10.7 53.1 11.4 15.8 23.2 32.0 3.7 20.1 28.6 49.4 4.0 16.1 23.4 12.9 13.9 28.4 56.8 10.0 11.8 22.3 35.1 13.1 20.0 19.0 49.9 54.8 25.1 17.6 37.8 31.5 21.4 11.3 50.9 LSM10 MGC15749 ENSG00000181817 "LSM10, U7 small nuclear RNA associated" Q969L4 1 36391238-36397908 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048469 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nuclear bodies" "HPA048469: AB_2756307" "unprognostic (2.15e-2)" "unprognostic (4.10e-2)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (6.21e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (1.90e-2)" "prognostic favorable (4.89e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.40e-6)" "unprognostic (1.84e-1)" "unprognostic (2.80e-1)" "unprognostic (3.59e-2)" "unprognostic (8.54e-2)" 39.2 32.7 53.1 32.0 54.2 23.9 32.8 54.5 67.5 31.9 55.0 62.3 20.1 36.3 30.4 26.8 31.6 22.7 72.9 53.4 58.7 42.3 51.7 30.6 52.3 54.4 55.2 31.7 30.5 36.9 41.8 18.0 55.3 40.8 17.7 9.7 29.1 30.5 165.0 30.1 36.7 27.9 55.2 55.3 38.7 28.9 57.8 27.2 31.0 110.3 47.6 42.8 28.2 54.3 54.6 81.2 29.9 80.7 68.9 67.2 31.0 47.9 69.4 75.1 57.1 36.4 50.6 127.4 64.5 65.0 55.6 29.3 51.2 62.1 49.5 87.1 61.2 64.1 47.1 87.1 83.8 49.0 90.3 56.8 54.4 67.6 47.6 40.7 77.8 71.7 60.2 60.5 53.4 96.3 54.8 55.5 77.5 67.0 83.3 40.9 28.8 86.3 73.6 32.6 38.1 28.7 38.7 49.4 120.6 47.9 25.5 41.3 52.2 34.0 47.3 90.0 76.0 79.5 115.7 102.4 68.4 73.9 78.7 240.2 264.1 340.1 125.3 266.4 139.0 386.4 125.1 132.0 189.4 388.0 112.1 120.7 346.4 111.6 256.4 243.9 172.3 301.8 53.1 54.2 54.5 67.5 53.4 58.7 54.4 55.2 55.3 55.2 57.8 54.3 27.8 12.8 14.4 3.9 82.2 32.2 37.2 53.3 13.1 17.4 40.9 44.4 55.9 21.5 30.4 46.0 6.2 56.1 58.5 23.4 140.8 40.7 9.7 18.6 32.7 31.7 28.2 40.2 8.6 47.1 58.8 36.8 19.4 23.3 41.2 25.7 32.2 66.8 105.7 18.5 9.1 23.4 63.1 77.0 89.3 32.9 38.8 67.6 51.6 7.5 72.0 41.0 66.9 3.5 6.7 47.4 35.3 47.0 67.0 40.3 47.7 106.4 12.4 14.3 13.1 28.4 38.8 7.8 23.4 27.7 40.1 40.0 51.0 43.3 28.5 27.3 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.5;intestine: 12.0;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in some" "B-cells: 244.0;dendritic cells: 36.2;Melanocytes: 71.2;Plasma cells: 102.5;T-cells: 44.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 112.9;MAIT T-cell: 113.5;memory B-cell: 56.1;memory CD4 T-cell: 97.6;memory CD8 T-cell: 109.8;naive B-cell: 52.8;naive CD4 T-cell: 109.6;naive CD8 T-cell: 112.3;plasmacytoid DC: 72.8;T-reg: 80.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 14.3;JURKAT: 14.1;Karpas-707: 28.0;U-266/70: 70.7;U-266/84: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" 2.4 0.9 0.1 13.7 0.2 11.5 2.0 0.1 0.2 0.8 0.2 3.9 4.0 0.6 0.4 0.9 0.9 2.5 0.5 0.1 0.2 1.1 2.3 3.8 30.2 0.3 0.2 0.6 0.2 0.0 0.2 0.3 0.2 1.1 3.8 0.0 7.1 0.4 0.3 0.8 12.0 0.5 0.3 26.7 6.0 0.2 0.2 25.5 1.4 0.2 31.1 3.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 28.0 0.0 0.0 2.3 0.5 0.1 0.8 0.0 1.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 70.7 29.3 0.3 0.0 4.0 0.0 1.2 0.8 0.4 112.9 1.1 113.5 56.1 97.6 109.8 5.2 52.8 109.6 112.3 2.4 22.2 0.8 72.8 80.3 53.5 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.2 0.4 0.0 1.8 0.3 244.0 1.0 0.5 0.1 0.0 0.0 0.4 0.8 0.9 0.0 0.0 0.0 0.0 0.1 36.2 0.1 0.0 0.0 0.1 0.1 0.1 0.7 1.2 28.0 0.1 0.2 0.0 1.4 0.5 0.1 0.0 0.0 1.8 0.4 1.9 0.0 0.1 0.0 0.0 3.2 31.9 0.0 0.0 6.3 71.2 1.9 2.1 0.0 22.6 0.0 0.1 0.1 0.0 0.0 102.5 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.6 0.0 0.1 0.5 1.0 0.1 44.8 0.0 0.3 0.3 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 LYSMD2 MGC35274 ENSG00000140280 "LysM domain containing 2" Q8IV50 15 51723011-51751585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 164.4;monocytes: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 77.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040460 Approved Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nuclear bodies" "HPA040460: AB_10794874" "unprognostic (7.71e-3)" "unprognostic (2.69e-1)" "unprognostic (3.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.11e-2)" "unprognostic (1.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.60e-1)" "unprognostic (1.85e-1)" "unprognostic (3.98e-1)" "unprognostic (4.17e-3)" "unprognostic (6.86e-2)" "unprognostic (1.58e-2)" "unprognostic (5.03e-1)" "unprognostic (4.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" 11.6 19.7 33.0 22.2 34.0 15.1 8.7 30.9 42.0 10.4 22.3 12.7 15.8 10.7 11.1 8.7 10.9 11.4 7.1 33.8 39.6 11.5 21.1 14.4 29.0 34.1 33.2 8.5 12.9 10.7 22.8 9.5 39.3 9.4 9.7 7.6 7.3 13.8 18.3 5.6 13.6 11.7 32.4 21.3 12.0 11.0 35.0 17.9 8.1 13.1 25.7 12.8 8.8 29.4 14.6 10.6 1.7 13.2 4.4 8.4 0.1 16.8 9.2 20.0 25.8 1.3 13.0 56.9 2.4 9.0 23.1 21.0 11.0 11.1 14.0 55.1 5.4 15.9 8.9 0.2 9.3 38.2 6.9 8.4 22.0 8.2 8.6 9.0 12.1 20.5 0.7 0.0 6.5 21.0 14.8 47.6 4.6 0.6 14.5 23.1 0.2 20.6 19.9 11.5 45.3 11.5 16.2 0.4 29.8 2.5 11.7 28.5 7.8 19.8 11.1 20.9 23.7 0.0 0.0 0.2 10.1 77.4 15.1 0.3 39.5 76.6 29.8 48.8 42.3 47.0 29.1 36.3 33.4 49.7 35.6 29.4 112.5 34.9 62.0 54.4 19.4 40.4 33.0 34.0 30.9 42.0 33.8 39.6 34.1 33.2 39.3 32.4 35.0 29.4 45.7 3.2 4.8 18.3 70.8 19.4 31.2 8.0 20.5 16.7 17.5 23.4 3.3 22.8 6.4 14.7 0.0 1.2 89.1 4.1 25.4 16.7 164.4 2.6 2.8 32.3 79.8 17.2 25.4 18.3 0.8 15.6 15.3 0.9 12.7 4.3 27.8 14.6 38.0 32.0 28.7 16.2 8.2 46.4 24.7 71.2 16.1 49.0 7.2 23.4 97.4 7.0 45.3 15.1 7.3 10.8 17.1 15.8 5.1 38.5 32.6 29.0 9.9 4.1 26.3 14.1 24.0 5.0 8.3 31.7 16.2 0.8 51.3 12.4 21.2 24.6 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 74.0;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;hTCEpi: 13.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 57: B-cells - Immune response" Vesicles "HPA053478: AB_2682165" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 7.1 12.4 1.9 1.5 2.4 7.0 6.4 4.7 2.2 6.5 2.2 6.7 1.6 6.1 0.2 3.8 6.3 1.3 6.6 1.1 2.1 4.8 4.7 10.5 2.1 3.8 2.9 8.8 8.3 3.0 5.0 3.7 4.7 4.3 1.1 2.7 8.9 2.0 3.0 4.5 8.5 2.4 3.0 12.0 9.1 1.6 3.5 1.2 7.1 0.1 2.0 8.1 5.8 3.7 2.9 1.4 0.6 1.6 15.5 12.1 0.9 1.1 6.9 1.8 4.1 1.7 1.0 3.6 1.4 2.7 3.9 1.0 3.0 2.2 1.1 2.2 0.7 3.0 1.1 0.7 2.7 2.8 8.2 3.7 13.7 7.6 3.4 8.9 3.0 1.2 3.6 2.0 3.4 1.4 2.0 2.3 1.3 1.9 1.1 1.9 1.6 0.6 3.4 2.3 1.4 0.5 1.4 1.9 1.5 5.4 4.5 1.8 0.2 2.0 1.3 9.3 1.2 1.3 5.8 0.5 3.1 1.5 1.6 4.0 6.8 16.6 0.4 6.1 0.7 1.7 0.0 0.7 5.3 2.1 0.4 0.6 6.1 1.8 9.1 1.2 0.5 3.1 1.9 2.4 4.7 2.2 1.1 2.1 3.8 2.9 4.7 3.0 3.5 3.7 6.4 32.1 35.6 24.5 45.4 5.9 8.4 13.2 12.0 6.2 11.6 8.1 14.6 14.3 13.5 9.2 6.2 42.3 14.3 5.1 1.9 8.1 2.8 6.9 6.9 8.1 1.8 19.7 36.4 2.7 7.3 13.8 25.5 12.8 34.8 5.5 10.4 17.7 43.6 6.7 66.5 10.5 2.0 58.5 29.6 1.6 9.0 74.0 0.0 111.5 52.8 5.2 17.5 31.2 66.8 5.5 17.3 19.9 17.5 7.5 5.2 9.8 5.8 7.5 0.0 10.8 6.7 0.2 1.4 12.6 4.5 22.6 16.9 12.6 11.2 9.7 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.5;THP-1: 51.0" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 57: B-cells - Immune response" Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 5.5 3.8 3.0 13.3 2.6 24.0 20.1 4.0 2.1 7.0 6.2 5.4 6.3 7.5 6.6 10.0 9.7 5.7 3.7 2.1 2.7 9.9 6.0 7.5 18.1 3.9 3.2 7.2 9.8 7.1 1.3 11.4 3.7 5.4 6.3 26.9 18.5 8.3 1.7 19.7 6.5 5.7 3.8 20.5 8.1 8.3 3.5 9.9 16.2 4.4 24.0 6.7 6.4 3.9 13.3 7.9 12.1 8.1 1.9 1.5 20.3 2.5 3.3 7.6 10.6 37.1 9.7 11.9 0.9 3.0 6.5 6.7 10.1 4.6 10.5 4.0 4.4 6.6 3.4 17.5 4.7 10.6 17.6 1.9 4.8 2.4 3.8 2.1 3.3 4.0 5.8 20.7 2.0 5.8 7.4 14.2 5.6 6.8 1.0 11.5 8.6 41.1 13.2 13.6 5.1 52.5 7.6 9.5 21.5 10.7 26.0 51.0 9.8 0.7 6.4 2.9 4.7 15.0 8.2 22.1 1.2 6.1 13.2 6.3 3.1 0.7 0.8 4.5 0.7 4.0 2.4 1.1 1.8 3.3 1.5 0.5 1.7 1.7 4.9 1.0 3.8 1.7 3.0 2.6 4.0 2.1 2.1 2.7 3.9 3.2 3.7 3.8 3.5 3.9 20.8 6.4 9.8 17.9 102.5 52.4 15.1 17.1 43.9 14.9 73.2 30.6 3.5 48.6 15.9 36.8 47.9 15.1 31.9 7.3 7.9 18.9 2.0 25.0 20.6 24.0 10.2 14.5 11.7 14.8 8.6 10.7 14.3 43.7 7.6 20.0 21.8 15.0 32.3 28.6 31.8 11.4 6.1 76.0 48.4 3.6 5.3 66.5 37.4 69.3 99.1 11.6 9.2 210.1 12.5 12.9 7.7 1.9 41.5 14.8 10.6 20.7 11.0 38.5 6.6 9.3 11.9 8.6 17.9 69.1 54.7 6.7 31.6 15.4 9.7 12.0 MAPK8IP3 "JIP3, JSAP1, KIAA1066, syd" ENSG00000138834 "Mitogen-activated protein kinase 8 interacting protein 3" Q9UPT6 16 1706183-1770351 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.1;Horizontal cells: 87.5;Inhibitory neurons: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005580, HPA041785, HPA069311" Approved Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 57: B-cells - Immune response" Vesicles "CAB005580: AB_627840, HPA041785: AB_2677671, HPA069311: AB_2686116" "unprognostic (1.49e-1)" "unprognostic (2.22e-1)" "unprognostic (8.28e-3)" "unprognostic (8.32e-2)" "unprognostic (3.90e-1)" "unprognostic (6.83e-3)" "unprognostic (3.66e-2)" "unprognostic (2.41e-2)" "unprognostic (1.55e-1)" "unprognostic (8.67e-2)" "unprognostic (1.57e-2)" "unprognostic (6.91e-3)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (2.45e-1)" "prognostic favorable (3.95e-4)" 25.1 32.2 29.3 13.5 36.5 26.4 26.1 16.2 64.9 38.6 0.0 26.9 13.5 25.9 4.0 20.2 31.7 7.9 39.3 39.7 18.5 34.1 30.8 31.7 16.3 39.5 17.4 46.8 39.3 7.0 78.6 8.5 34.9 43.6 3.8 11.3 28.8 7.4 22.1 37.0 39.4 4.4 7.9 49.8 25.9 32.0 18.4 11.8 38.3 4.3 6.5 35.2 30.5 44.9 6.5 12.2 12.7 11.4 6.1 10.3 9.9 10.7 4.0 5.2 4.6 17.3 21.0 7.5 6.6 6.7 3.7 12.1 3.1 7.0 1.7 11.9 14.1 10.0 33.6 13.4 8.4 6.5 16.9 20.7 9.2 7.6 3.7 22.9 6.9 14.1 8.6 14.1 5.5 16.6 10.2 28.5 8.5 3.2 6.9 44.1 6.3 12.9 6.4 8.4 26.4 21.0 12.8 11.8 5.3 5.8 6.4 9.1 21.9 21.8 12.2 9.4 8.6 31.4 5.8 9.7 5.7 6.7 11.1 0.0 0.2 0.5 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.1 29.3 36.5 16.2 64.9 39.7 18.5 39.5 17.4 34.9 7.9 18.4 44.9 9.1 3.2 7.8 46.7 30.5 9.8 4.3 10.0 13.1 40.8 7.9 7.5 6.6 10.0 10.5 3.7 37.5 5.6 10.4 16.8 1.9 4.9 24.9 13.2 13.0 7.8 10.2 8.6 62.1 3.8 5.7 7.5 34.7 21.9 1.3 23.4 6.4 9.7 7.2 87.5 65.2 11.1 10.2 10.3 12.5 23.4 7.8 13.5 7.2 31.9 8.7 11.9 9.2 32.6 52.8 7.7 9.5 9.1 17.6 4.7 10.3 1.2 15.9 19.2 6.6 7.3 8.2 19.8 5.1 10.8 9.7 5.6 11.8 5.9 11.7 6.0 MATN1 "CMP, CRTM" ENSG00000162510 "Matrilin 1" P21941 1 30711277-30723585 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.3;retina: 5.2" "Cell type enhanced" "Detected in some" "B-cells: 4.1;Paneth cells: 1.1" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 1.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028580 Supported "Secreted to extracellular matrix" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 57: B-cells - Immune response" "HPA028580: AB_10601913" "unprognostic (4.71e-2)" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (3.75e-6)" "unprognostic (9.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.31e-3)" "unprognostic (2.63e-1)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (7.31e-2)" "unprognostic (5.22e-2)" "unprognostic (4.01e-13)" "unprognostic (8.23e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (3.42e-2)" 0.0 0.1 0.4 0.3 0.5 0.7 0.0 0.4 0.4 0.5 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.5 0.6 0.4 0.7 0.2 0.0 0.2 0.3 0.7 0.1 0.0 5.2 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.4 0.1 0.2 0.4 0.0 0.3 0.0 0.0 0.1 0.2 1.3 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.3 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.0 0.7 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.5 0.4 0.4 0.2 0.4 0.6 0.4 0.7 0.3 0.4 1.3 0.3 0.0 0.5 0.0 4.1 0.1 0.6 0.1 0.0 0.0 0.4 1.0 0.5 0.0 0.6 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.4 0.2 0.3 0.2 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 1.1 0.4 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.5 0.2 0.8 0.5 0.5 0.1 0.3 0.5 0.3 0.0 0.1 MBD4 MED1 ENSG00000129071 "Methyl-CpG binding domain 4, DNA glycosylase" O95243 3 129430947-129440179 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002031 Supported Supported "Nuclear speckles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" "HPA002031: AB_1079319" "unprognostic (2.70e-2)" "unprognostic (3.48e-3)" "unprognostic (1.18e-2)" "unprognostic (6.37e-2)" "unprognostic (4.31e-2)" "unprognostic (7.11e-2)" "unprognostic (4.70e-2)" "unprognostic (3.25e-2)" "unprognostic (2.02e-2)" "unprognostic (5.73e-2)" "prognostic unfavorable (2.18e-4)" "prognostic unfavorable (4.75e-4)" "prognostic unfavorable (2.73e-6)" "unprognostic (9.27e-2)" "unprognostic (1.59e-2)" "unprognostic (8.58e-2)" "unprognostic (3.35e-2)" 18.6 18.4 16.8 34.0 18.4 44.2 21.6 19.6 20.7 33.2 16.8 19.3 23.7 23.3 24.8 16.4 19.3 21.3 25.3 17.0 17.4 25.4 38.0 22.9 66.5 17.5 17.2 30.3 22.9 18.1 19.3 19.7 17.7 18.7 22.9 19.6 19.5 17.8 25.8 23.7 27.5 19.7 17.3 39.2 27.8 17.3 18.4 30.0 19.3 22.3 74.0 18.5 17.5 20.6 46.2 27.4 32.5 36.5 36.8 32.8 37.5 39.0 36.9 36.7 43.3 33.8 30.1 64.6 31.1 24.5 33.7 40.7 25.2 24.1 44.2 37.0 16.6 38.9 32.0 24.6 58.7 71.2 49.2 39.1 33.8 31.2 27.4 36.5 35.1 37.2 43.9 47.1 27.5 43.3 41.4 50.0 28.7 38.8 23.5 38.7 19.2 44.7 40.9 22.7 36.5 20.3 49.3 25.3 42.5 28.0 32.3 62.5 23.6 34.5 26.3 37.6 26.2 31.9 20.9 111.9 29.4 40.1 29.2 80.3 25.0 35.2 31.1 23.1 24.0 116.5 33.2 30.9 21.0 110.8 40.6 33.3 43.0 28.9 30.0 25.2 31.5 25.6 16.8 18.4 19.6 20.7 17.0 17.4 17.5 17.2 17.7 17.3 18.4 20.6 36.5 19.2 52.9 15.3 111.2 17.3 32.5 38.4 29.6 37.0 26.7 29.6 35.9 27.1 36.4 44.1 18.8 49.2 61.4 22.4 45.0 32.1 19.8 49.6 41.2 33.5 33.6 46.3 18.1 69.0 46.2 35.6 55.0 45.0 58.9 33.1 31.4 32.1 71.8 21.9 12.8 27.5 40.7 41.8 24.7 10.6 32.9 48.0 21.4 24.4 62.9 21.2 54.6 14.1 22.0 39.3 23.4 36.5 75.5 31.1 29.4 55.5 39.5 46.3 39.5 39.6 30.9 49.5 71.6 30.4 19.6 37.1 54.2 33.2 26.3 35.6 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 METTL8 "FLJ13984, TIP" ENSG00000123600 "Methyltransferase like 8" 2 171317405-171434802 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035421 Uncertain Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Cytosol "HPA035421: AB_10670116" "unprognostic (3.13e-1)" "unprognostic (2.72e-1)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.76e-1)" "unprognostic (3.76e-1)" "unprognostic (1.43e-4)" "unprognostic (2.94e-3)" "unprognostic (7.29e-2)" "unprognostic (6.52e-3)" "unprognostic (4.83e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.45e-1)" "unprognostic (2.04e-1)" "unprognostic (2.10e-3)" "unprognostic (2.59e-3)" 3.6 2.8 2.8 3.2 4.7 3.6 3.7 2.5 3.9 3.4 1.8 5.3 2.2 3.0 2.1 8.6 2.4 2.8 2.5 2.6 1.9 3.1 3.6 2.0 3.5 2.7 2.4 2.2 1.7 2.1 1.2 2.6 2.9 3.9 5.2 1.6 2.1 4.0 3.6 6.8 3.6 6.4 2.0 3.3 2.1 4.2 2.8 2.1 1.8 2.3 3.9 5.2 3.8 4.0 10.3 7.4 5.0 13.0 11.7 14.1 19.1 12.8 9.8 11.1 10.0 13.8 13.5 25.1 9.5 8.1 8.2 10.0 17.7 19.4 13.9 10.8 9.9 15.0 6.5 25.0 11.1 17.0 9.1 12.5 24.7 16.0 28.1 2.6 18.6 10.9 26.7 4.1 9.7 13.5 14.3 4.8 16.9 8.3 8.8 7.0 15.4 21.9 9.1 6.8 12.2 5.1 14.5 11.4 9.2 6.6 9.4 7.0 13.8 11.4 6.1 7.6 7.5 3.6 13.0 15.0 7.2 15.9 11.2 0.5 2.1 0.5 3.4 2.7 4.4 3.4 4.4 3.3 2.1 5.1 1.9 2.1 0.7 3.7 1.6 6.7 4.8 2.5 2.8 4.7 2.5 3.9 2.6 1.9 2.7 2.4 2.9 2.0 2.8 4.0 8.1 6.4 6.1 25.1 72.3 25.5 10.7 18.3 27.9 8.4 10.6 9.1 8.2 14.3 14.1 3.7 2.1 15.5 13.1 8.4 11.7 7.6 13.3 4.0 19.2 8.2 6.7 16.2 28.7 6.2 21.2 14.9 6.1 6.1 6.3 18.5 7.5 10.6 11.8 11.8 33.0 5.7 12.2 9.8 10.2 4.1 14.0 11.9 10.6 17.8 11.4 6.3 7.2 29.1 48.2 8.8 5.3 16.1 24.2 20.4 9.8 18.3 6.4 9.2 6.6 10.8 10.8 11.8 21.3 32.8 26.7 12.9 18.3 23.0 13.7 10.0 MIOS "FLJ20323, MIO, Sea4, Yulink" ENSG00000164654 "Meiosis regulator for oocyte development" Q9NXC5 7 7566875-7608932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042928, HPA052223" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA042928: AB_10795610, HPA052223: AB_2681768" "unprognostic (8.09e-3)" "unprognostic (1.25e-2)" "unprognostic (6.93e-2)" "prognostic favorable (6.51e-4)" "unprognostic (3.42e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (1.44e-2)" "unprognostic (2.27e-1)" "unprognostic (2.09e-1)" "prognostic favorable (3.28e-6)" "unprognostic (1.03e-1)" "unprognostic (1.10e-2)" "unprognostic (7.67e-3)" "unprognostic (2.72e-1)" 10.0 9.5 7.0 15.2 6.6 18.8 14.5 12.1 8.7 12.3 26.8 11.3 8.8 9.9 10.4 22.9 10.8 9.9 11.9 5.7 9.3 12.6 17.3 11.7 22.4 6.7 7.4 13.3 17.3 28.1 8.9 11.6 6.1 21.7 13.0 18.8 13.5 11.2 85.5 18.1 9.3 12.2 6.7 15.3 13.4 19.2 7.2 16.2 9.3 51.1 29.9 13.9 14.3 8.2 42.4 18.8 21.8 26.4 17.1 35.9 18.3 32.9 26.8 20.6 20.6 23.2 16.5 37.1 9.9 19.7 55.3 37.6 23.1 24.2 27.0 14.8 19.5 9.5 22.5 16.1 24.3 40.1 10.2 30.9 29.0 18.3 46.2 20.1 18.2 12.4 47.2 29.4 88.0 29.1 9.2 17.0 45.3 21.3 19.8 27.4 33.4 36.3 19.0 21.3 23.0 37.2 17.7 49.1 19.3 40.5 26.7 35.1 15.7 31.3 33.2 17.4 27.7 25.9 30.9 33.2 27.6 23.0 37.2 0.0 5.4 8.8 4.3 9.9 3.6 10.1 4.6 4.2 7.6 8.8 6.0 4.9 0.6 5.4 5.0 4.5 5.1 4.0 7.0 6.6 12.1 8.7 5.7 9.3 6.7 7.4 6.1 6.7 7.2 8.2 8.2 9.6 11.9 18.6 30.3 12.1 14.8 6.6 15.4 8.2 13.2 10.8 18.2 12.8 9.2 7.3 12.5 16.8 12.2 9.0 17.6 11.7 38.5 22.7 11.4 7.5 4.2 15.6 22.9 17.5 8.7 9.3 16.3 18.6 9.5 15.4 6.8 17.0 15.5 11.8 21.0 7.2 4.1 22.7 12.2 57.9 5.9 18.4 7.2 27.2 10.1 9.4 13.4 23.1 18.2 14.1 11.3 7.5 19.4 24.9 6.7 11.3 11.0 17.0 13.1 13.1 9.3 36.0 30.4 24.8 18.9 21.2 15.3 15.3 11.1 19.7 MS4A1 "B1, Bp35, CD20, MS4A2" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 673.3" "Cell type enriched" "Detected in some" 35 "B-cells: 970.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 625.4;naive B-cell: 627.0" "Lineage enriched" "Detected in many" 96 "B-cells: 627.0" "Group enriched" "Detected in some" 26 "Daudi: 731.3;U-698: 364.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "CAB000015: AB_2282030, HPA014341: AB_1846265, HPA014391: AB_1846264" "prognostic favorable (4.34e-5)" "unprognostic (4.45e-4)" "unprognostic (1.19e-4)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (5.53e-7)" "unprognostic (2.46e-3)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.89e-4)" "unprognostic (6.96e-2)" "unprognostic (2.84e-2)" "unprognostic (3.96e-5)" "unprognostic (2.23e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" 3.6 0.4 0.0 149.7 0.0 19.1 0.8 0.0 0.1 0.5 0.1 9.0 3.0 2.2 1.0 4.2 0.5 8.4 1.8 0.0 0.1 3.4 2.1 4.0 500.4 0.2 0.0 0.3 0.2 7.3 0.3 0.9 0.1 5.1 10.6 0.0 8.9 0.3 0.8 0.1 123.5 1.2 0.1 253.8 18.4 1.2 0.1 50.6 6.7 0.1 673.3 16.3 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 731.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.5 0.2 0.0 0.1 0.0 364.1 0.0 0.2 0.0 0.8 0.5 0.3 2.4 0.1 3.7 625.4 2.8 5.5 0.5 627.0 0.5 2.1 2.0 6.5 0.6 0.5 0.8 32.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 3.8 0.0 970.5 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 4.5 0.7 0.1 0.3 0.0 7.0 0.0 0.0 0.1 1.8 2.0 0.1 2.5 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.0 0.6 0.3 2.0 0.0 4.6 7.2 0.0 2.5 0.0 2.1 0.0 0.0 0.0 0.3 0.0 9.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.8 0.1 0.0 27.3 0.7 0.2 0.0 NCF1 "NCF1A, NOXO2, p47phox, SH3PXD1A" ENSG00000158517 "Neutrophil cytosolic factor 1" P14598 7 74773962-74789376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.4;lymphoid tissue: 97.5" "Cell type enhanced" "Detected in many" "B-cells: 293.0;dendritic cells: 157.3;Kupffer cells: 119.9;Macrophages: 153.4;monocytes: 329.9;Plasma cells: 205.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1165.0;classical monocyte: 673.5;eosinophil: 1467.3;neutrophil: 2128.0" "Group enriched" "Detected in all" 5 "granulocytes: 2128.0;monocytes: 673.5" "Group enriched" "Detected in some" 5 "Daudi: 96.2;HMC-1: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004524, HPA047836, HPA052095" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB004524: AB_627987, HPA047836: AB_2680173, HPA052095: AB_2681721" "unprognostic (4.93e-2)" "unprognostic (8.34e-3)" "unprognostic (1.23e-1)" "unprognostic (1.25e-2)" "unprognostic (8.67e-2)" "unprognostic (3.55e-3)" "unprognostic (7.60e-2)" "unprognostic (4.75e-2)" "unprognostic (6.23e-3)" "unprognostic (9.99e-2)" "unprognostic (6.61e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-3)" "unprognostic (3.16e-1)" "unprognostic (4.17e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-1)" 7.5 3.8 1.9 38.7 2.2 86.4 2.7 4.6 2.9 1.7 0.9 7.2 7.6 1.3 0.5 3.3 3.2 5.5 3.0 2.8 2.0 2.9 5.0 17.7 56.8 5.0 3.4 1.1 1.5 0.7 1.2 5.0 4.5 2.1 4.5 1.6 4.2 1.4 1.5 1.8 26.6 4.0 2.4 97.5 6.6 0.8 2.3 7.5 2.6 4.8 37.5 7.6 1.8 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.1 96.2 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.5 0.6 2.9 1.4 0.9 0.0 0.8 130.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.1 16.8 0.3 0.0 0.0 1.6 0.0 3.4 0.2 0.4 0.0 0.1 0.0 0.1 0.1 0.1 0.0 20.6 0.2 0.1 0.3 0.2 0.0 0.6 0.3 16.5 0.2 8.1 0.2 1165.0 673.5 1467.3 4.2 242.3 9.8 257.0 10.0 6.7 77.7 276.6 15.4 9.4 2128.0 10.7 60.2 280.9 11.1 514.1 1.9 2.2 4.6 2.9 2.8 2.0 5.0 3.4 4.5 2.4 2.3 6.6 5.0 0.0 2.8 0.0 293.0 3.1 1.1 29.6 5.2 0.2 3.1 3.2 0.6 4.3 10.9 3.7 0.0 0.6 157.3 0.0 0.0 1.3 8.7 0.8 1.0 3.6 0.0 6.1 0.0 0.6 12.2 1.5 10.2 2.5 14.5 0.1 3.9 3.6 39.3 3.3 0.1 0.3 2.0 119.9 23.4 6.4 0.0 153.4 10.6 1.0 329.9 0.3 10.3 0.0 0.1 1.2 4.2 0.4 205.7 1.0 0.4 1.9 17.6 0.5 0.0 1.4 1.5 0.2 0.7 5.0 1.7 4.5 63.6 0.1 0.3 2.2 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 NCOA3 "ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1" ENSG00000124151 "Nuclear receptor coactivator 3" Q9Y6Q9 20 47501887-47656877 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 155.8;Plasma cells: 168.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 187.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009800, HPA024210" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "CAB009800: AB_2251314, HPA024210: AB_10602011" "unprognostic (7.26e-3)" "unprognostic (1.00e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-2)" "unprognostic (5.78e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (8.09e-4)" "unprognostic (2.83e-2)" "unprognostic (1.47e-1)" "unprognostic (5.22e-3)" "unprognostic (2.09e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-2)" "unprognostic (4.18e-1)" "unprognostic (1.63e-1)" 14.7 8.2 4.7 22.9 4.7 13.4 11.5 5.7 9.0 11.1 3.8 9.9 8.8 11.8 7.1 14.3 10.7 10.3 13.3 4.0 5.5 9.4 10.5 14.8 35.0 6.5 5.3 14.1 11.1 11.2 6.0 28.1 6.9 9.6 11.2 11.6 11.3 8.8 25.2 14.0 14.8 11.5 5.3 27.5 14.8 7.5 5.9 17.9 12.9 16.5 39.2 15.3 12.5 6.4 17.6 50.1 16.1 21.5 37.5 41.9 105.2 16.4 24.2 27.3 14.1 25.2 19.0 61.8 11.0 28.5 36.1 43.2 12.2 20.7 20.9 31.3 6.4 8.1 15.3 39.3 22.6 6.8 43.3 19.9 61.2 24.4 30.3 23.5 20.0 10.0 18.7 14.0 16.2 187.0 9.9 12.8 5.8 14.2 20.6 17.8 11.0 27.4 16.8 38.2 3.1 5.7 41.0 53.7 18.8 18.0 24.3 17.8 35.8 16.4 12.9 20.5 7.4 38.5 35.9 60.6 19.4 7.0 10.8 2.8 3.9 3.0 2.5 5.2 2.2 9.3 2.3 2.2 5.0 6.8 2.6 2.9 4.5 2.1 5.0 4.2 3.1 2.6 4.7 4.7 5.7 9.0 4.0 5.5 6.5 5.3 6.9 5.3 5.9 6.4 86.7 12.8 23.7 27.7 155.8 34.5 15.7 25.0 52.9 18.1 23.8 13.8 26.1 20.0 29.0 14.7 8.4 69.5 39.9 12.5 5.9 12.9 12.1 36.4 29.1 49.8 14.9 14.9 48.5 19.6 26.2 26.4 26.5 78.8 8.8 15.3 68.2 20.0 22.8 13.5 64.3 10.7 36.7 46.8 62.2 6.0 24.8 58.2 33.8 109.6 46.1 9.3 28.8 49.3 54.1 21.0 16.9 27.4 168.8 28.1 9.0 6.5 39.8 23.8 19.7 19.7 30.3 43.2 30.0 63.3 51.7 89.2 47.6 14.2 11.7 59.2 NIPA2 SLC57A2 ENSG00000140157 "NIPA magnesium transporter 2" Q8N8Q9 15 22838644-22869362 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067160, HPA071342" Approved Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "HPA067160: AB_2685794, HPA071342: AB_2686391" "unprognostic (2.88e-3)" "unprognostic (1.82e-1)" "unprognostic (9.34e-3)" "unprognostic (1.17e-1)" "unprognostic (4.49e-1)" "unprognostic (2.34e-1)" "unprognostic (3.02e-2)" "unprognostic (1.22e-2)" "unprognostic (2.80e-1)" "unprognostic (1.38e-1)" "unprognostic (2.46e-3)" "unprognostic (2.94e-1)" "unprognostic (7.75e-3)" "unprognostic (3.53e-2)" "unprognostic (1.59e-1)" "unprognostic (3.22e-2)" "unprognostic (2.93e-2)" 24.0 26.9 15.5 35.0 15.4 30.6 20.7 14.8 16.3 21.2 19.1 40.5 39.7 21.1 18.5 25.5 17.1 24.7 18.9 15.5 17.3 31.0 27.3 23.0 36.3 15.3 17.4 15.0 24.2 25.5 18.5 28.7 17.1 26.4 38.9 15.9 26.6 17.1 27.5 15.3 35.7 24.4 16.3 27.1 28.5 16.9 16.5 28.7 26.8 27.2 42.9 34.8 15.3 16.6 103.6 103.7 51.7 61.7 55.9 58.1 57.3 117.3 99.1 78.4 90.4 76.5 64.3 101.0 70.6 71.7 88.6 82.6 99.9 58.3 77.3 109.7 61.0 89.9 66.4 61.2 72.3 127.0 81.8 54.9 61.2 64.2 65.5 51.6 87.7 79.2 137.4 117.1 99.8 39.2 40.1 56.0 60.2 109.9 99.9 88.3 87.0 74.9 71.6 120.9 69.4 71.7 95.6 84.8 98.9 48.4 74.4 114.3 91.4 104.0 65.6 73.2 237.5 90.0 153.3 107.4 76.3 129.9 88.2 72.1 44.5 38.9 41.1 55.4 46.9 76.3 36.9 45.4 54.9 67.1 34.2 34.6 32.7 48.6 55.7 82.0 52.8 49.2 15.5 15.4 14.8 16.3 15.5 17.3 15.3 17.4 17.1 16.3 16.5 16.6 26.0 16.0 23.1 10.7 62.9 45.0 41.3 26.1 20.5 9.4 25.2 16.5 3.8 22.8 25.0 12.9 12.5 39.9 45.0 53.7 21.5 39.6 10.7 21.7 24.5 28.5 24.4 29.2 14.7 43.8 65.4 23.4 26.0 27.6 10.1 26.2 22.9 22.1 48.3 21.9 15.4 30.2 38.7 30.3 41.3 3.3 13.4 35.5 23.2 14.0 31.4 27.3 35.0 9.5 13.3 57.8 31.1 21.1 60.8 56.5 31.8 23.3 20.6 13.0 13.1 17.6 28.6 32.8 35.2 28.8 57.8 84.4 37.3 38.7 38.1 89.7 NKX6-3 FLJ25169 ENSG00000165066 "NK6 homeobox 3" A6NJ46 8 41645177-41650817 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 10.8;stomach 1: 28.0" "Cell type enriched" "Detected in single" 5 "Gastric mucus-secreting cells: 2.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.1;stomach cancer: 3.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Daudi: 4.9;THP-1: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.87e-1)" "unprognostic (9.91e-3)" "unprognostic (4.04e-1)" "unprognostic (5.73e-2)" "unprognostic (1.98e-1)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "unprognostic (1.13e-1)" "unprognostic (2.17e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.3 0.1 0.5 0.1 0.0 2.5 1.0 0.0 0.3 0.1 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 1.5 0.5 0.9 0.0 0.9 1.8 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.3 28.0 0.1 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 2.5 1.0 0.4 0.4 0.5 0.9 0.6 0.4 0.4 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NRROS "ELLP3030, GARPL1, LRRC33, MGC50789, UNQ3030" ENSG00000174004 "Negative regulator of reactive oxygen species" Q86YC3 3 196639694-196662004 "Disease related genes, Predicted membrane proteins" "Growth factor binding" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.7" "Cell type enhanced" "Detected in many" "B-cells: 40.2;Erythroid cells: 27.5;Hofbauer cells: 76.9;Kupffer cells: 35.5;Langerhans cells: 59.9;Macrophages: 33.3;Microglial cells: 31.9;NK-cells: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 4.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.3;granulocytes: 4.2;monocytes: 1.1" "Cell line enhanced" "Detected in many" "HEL: 53.1;HMC-1: 106.4;Karpas-707: 66.7;MOLT-4: 59.8;NB-4: 138.5;RPMI-8226: 68.9;THP-1: 60.5;U-937: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031586 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "HPA031586: AB_10601543" "unprognostic (5.28e-2)" "unprognostic (8.92e-3)" "unprognostic (1.02e-1)" "unprognostic (3.05e-2)" "unprognostic (2.23e-1)" "unprognostic (1.41e-3)" "unprognostic (1.05e-1)" "unprognostic (9.67e-2)" "unprognostic (3.20e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (2.32e-2)" "unprognostic (2.81e-1)" "unprognostic (6.73e-3)" "unprognostic (1.47e-1)" "unprognostic (7.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" 7.8 2.6 1.9 8.6 1.5 32.7 5.1 1.5 1.6 2.5 1.6 2.7 2.4 2.9 0.5 2.0 2.8 4.2 2.9 1.8 3.0 2.8 2.5 7.7 10.5 2.7 1.9 1.2 1.1 0.9 1.2 9.9 2.7 2.0 1.6 0.3 2.4 1.6 1.3 2.0 5.1 4.1 2.7 15.7 2.3 1.3 3.4 7.7 2.2 2.5 3.6 4.5 2.1 4.4 0.1 0.0 0.3 0.0 0.4 1.0 0.1 0.4 2.1 0.4 0.3 0.1 0.2 0.0 6.7 0.4 0.3 0.1 1.1 0.0 0.1 4.0 0.1 53.1 0.0 0.0 0.5 43.7 106.4 0.4 0.0 1.7 0.7 2.1 4.3 48.6 5.5 66.7 1.2 0.1 59.8 138.5 4.4 0.0 0.1 15.7 0.1 68.9 0.1 0.4 0.3 0.0 0.1 0.1 28.0 0.9 0.1 60.5 0.5 0.5 0.2 1.9 0.1 26.5 43.1 12.1 3.4 76.1 0.7 4.2 1.0 1.8 0.3 1.0 0.1 0.3 0.2 0.2 1.3 0.2 0.1 0.2 0.0 0.3 1.1 0.2 0.3 0.7 1.9 1.5 1.5 1.6 1.8 3.0 2.7 1.9 2.7 2.7 3.4 4.4 5.6 0.0 0.5 0.0 40.2 1.5 0.1 0.0 2.2 0.4 0.4 0.3 0.3 0.0 0.6 0.0 4.2 0.3 15.5 0.0 0.0 0.0 1.4 0.0 0.4 10.1 0.0 27.5 1.8 0.0 0.7 0.7 0.5 0.1 14.5 0.1 15.4 0.2 76.9 0.0 2.7 0.0 0.0 35.5 59.9 0.4 0.6 33.3 8.8 31.9 24.1 0.1 33.0 1.0 0.3 0.0 0.0 0.7 25.7 0.0 0.0 0.1 0.0 0.4 6.6 0.3 0.3 2.7 0.4 0.2 0.9 0.5 10.8 0.5 0.0 0.0 OGFR 7-60 ENSG00000060491 "Opioid growth factor receptor" Q9NZT2 20 62804835-62814000 "Predicted intracellular proteins" "Growth regulation" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 12.5;neutrophil: 3.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 12.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017899 Supported Approved Nucleoplasm NA NA 20000 "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA017899: AB_1854774" "unprognostic (1.33e-2)" "unprognostic (3.28e-2)" "unprognostic (2.32e-2)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-1)" "unprognostic (1.23e-2)" "unprognostic (5.87e-2)" "unprognostic (5.39e-3)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.46e-3)" "unprognostic (1.60e-2)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "prognostic favorable (5.19e-4)" 33.4 25.7 25.9 26.8 28.1 34.5 31.7 21.0 45.4 37.1 21.7 38.4 28.5 30.7 5.3 27.3 34.6 11.5 29.1 28.4 22.8 38.5 79.4 54.5 26.6 25.4 22.7 41.4 33.4 13.1 36.8 13.4 22.9 42.3 8.6 17.2 30.9 14.1 29.5 32.5 42.9 10.5 21.8 68.3 34.3 21.1 23.9 15.2 39.3 9.9 15.2 35.1 34.1 27.7 51.5 34.2 19.8 26.5 16.4 16.5 56.1 30.9 25.3 91.3 41.0 77.3 36.9 58.6 57.2 21.5 56.8 58.8 20.2 32.8 25.9 19.3 37.5 29.4 42.9 71.1 28.7 36.9 69.6 23.4 23.6 24.9 10.4 30.9 20.4 37.9 29.0 30.6 13.5 76.4 78.9 69.8 13.3 24.5 65.1 62.1 34.5 27.5 14.2 25.5 19.8 30.2 42.5 59.5 49.6 17.9 29.7 56.5 34.8 61.1 54.1 48.1 45.6 38.8 11.5 30.9 47.9 39.6 24.5 1.8 1.5 12.5 0.7 1.4 0.4 1.0 0.9 0.8 1.0 1.5 0.9 0.5 3.1 0.6 1.4 0.7 0.6 0.4 25.9 28.1 21.0 45.4 28.4 22.8 25.4 22.7 22.9 21.8 23.9 27.7 25.2 9.6 15.0 19.6 52.8 27.0 35.7 20.2 35.3 59.5 18.6 16.8 5.9 40.0 12.6 16.5 93.8 27.8 47.0 35.5 11.7 35.7 1.9 19.9 24.4 25.1 18.0 26.1 29.1 32.9 52.1 25.3 28.5 20.2 0.0 24.5 28.9 49.2 57.5 43.7 23.5 30.4 12.2 79.5 37.6 3.5 32.6 51.7 16.0 11.2 70.3 35.7 74.2 19.1 10.2 31.4 39.7 18.8 44.2 36.5 60.4 27.4 19.4 42.3 19.7 18.2 22.1 5.7 8.9 19.2 23.3 27.9 44.7 20.5 24.2 32.3 ORAI2 "C7orf19, CBCIP2, FLJ12474, FLJ14733, H_NH0514P08.8, TMEM142B" ENSG00000160991 "ORAI calcium release-activated calcium modulator 2" Q96SN7 7 102433106-102456825 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 140.4;Endometrial ciliated cells: 77.2;Glandular and luminal cells: 76.9;Plasma cells: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 75.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 149.0;RPMI-8226: 160.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055137, HPA065937" Uncertain Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA055137: AB_2682712, HPA065937: AB_2685581" "unprognostic (5.09e-3)" "unprognostic (1.23e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (5.07e-3)" "unprognostic (8.56e-2)" "unprognostic (3.82e-2)" "unprognostic (7.07e-2)" "unprognostic (7.61e-2)" "unprognostic (1.47e-1)" "prognostic favorable (8.49e-5)" "unprognostic (7.16e-2)" "unprognostic (1.57e-3)" "unprognostic (7.97e-2)" "unprognostic (1.88e-1)" "prognostic favorable (6.65e-4)" "unprognostic (2.46e-1)" 8.8 10.7 18.7 30.9 13.7 39.4 7.2 16.5 21.2 8.0 25.3 7.1 7.9 11.9 6.9 3.3 10.6 9.4 4.4 24.4 26.2 13.5 2.1 9.9 31.0 21.0 20.0 6.0 7.1 39.6 38.9 5.5 24.5 6.8 3.9 3.3 7.3 9.4 1.4 2.5 17.8 6.4 13.7 27.7 11.3 3.0 27.5 12.0 16.0 1.6 22.1 10.7 3.8 12.2 22.1 52.2 20.0 38.3 17.2 17.2 1.3 21.4 24.3 24.6 20.7 28.9 24.1 149.0 59.7 38.9 47.9 8.8 7.6 6.2 8.6 17.1 11.7 23.0 24.2 9.1 26.1 56.6 29.2 16.2 3.6 39.4 5.8 24.4 39.6 21.3 27.8 130.7 18.1 44.9 77.4 25.1 23.8 8.1 18.6 33.0 15.3 160.8 14.4 18.0 32.1 78.5 20.5 9.4 11.8 10.2 13.3 22.7 36.3 57.0 55.5 39.3 29.9 115.9 94.8 116.4 40.6 30.8 28.5 13.2 6.8 75.9 4.9 5.8 5.1 29.2 4.1 3.6 3.9 29.4 2.6 3.2 58.9 18.3 3.3 6.4 2.4 7.0 18.7 13.7 16.5 21.2 24.4 26.2 21.0 20.0 24.5 13.7 27.5 12.2 29.0 3.2 9.6 5.2 140.4 4.0 9.7 5.3 5.2 33.5 10.0 6.7 4.2 8.6 11.1 16.5 66.7 1.3 55.4 1.0 5.9 20.9 3.6 77.2 39.8 27.0 17.3 27.1 13.2 11.6 1.6 13.9 1.5 76.9 26.0 14.9 23.9 0.7 14.9 43.7 14.7 2.4 2.0 19.1 12.5 7.4 8.1 33.0 10.6 7.5 37.6 12.1 39.1 7.1 1.2 10.7 0.3 10.1 76.3 10.3 0.2 8.9 31.2 19.1 0.0 17.9 15.2 5.3 9.1 1.2 3.1 3.0 28.8 12.8 2.0 7.0 OSGEP "GCPL1, KAE1, OSGEP1, PRSMG1, TCS3" ENSG00000092094 "O-sialoglycoprotein endopeptidase" Q9NPF4 14 20446401-20455089 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039751 Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" Nucleoplasm "Plasma membrane" "HPA039751: AB_10794754" "prognostic favorable (1.48e-4)" "unprognostic (4.15e-3)" "unprognostic (1.29e-1)" "unprognostic (4.33e-3)" "unprognostic (1.54e-2)" "unprognostic (3.95e-2)" "unprognostic (5.54e-3)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.35e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (4.64e-6)" "unprognostic (4.83e-2)" "unprognostic (1.86e-2)" "unprognostic (2.53e-2)" "unprognostic (9.91e-2)" 5.7 6.3 6.1 3.8 6.2 6.1 7.0 6.4 7.3 6.8 6.8 7.6 3.8 6.4 8.5 6.0 6.1 6.6 8.1 6.0 6.3 5.8 11.1 6.2 9.3 6.4 6.1 5.3 5.6 7.4 5.2 6.7 6.4 4.9 7.0 4.1 5.3 8.3 10.5 4.7 6.2 5.6 6.5 8.4 6.4 2.4 6.3 9.9 7.6 9.9 10.1 8.2 4.9 6.9 10.3 17.2 5.6 16.2 9.9 6.6 17.6 8.0 11.3 21.1 20.1 21.5 12.3 21.1 10.3 11.0 9.0 8.6 17.9 17.6 14.1 16.8 19.1 14.8 12.2 32.1 7.4 24.3 19.7 5.3 5.2 26.1 14.0 4.6 14.3 18.8 14.0 12.1 17.6 21.0 25.0 11.8 9.1 31.5 31.8 35.3 10.3 12.4 12.8 11.7 21.3 4.2 15.4 16.0 11.9 3.3 9.7 23.7 6.1 8.7 21.2 11.3 10.7 3.4 18.0 31.7 5.0 36.1 11.0 9.3 29.2 38.5 18.8 27.9 17.4 28.7 19.7 17.2 44.5 38.1 15.9 17.4 13.8 20.9 23.3 16.9 19.2 24.6 6.1 6.2 6.4 7.3 6.0 6.3 6.4 6.1 6.4 6.5 6.3 6.9 27.1 35.3 34.9 16.3 46.0 11.5 20.9 26.2 14.2 37.8 24.0 25.1 17.2 15.7 29.1 23.9 37.5 66.3 31.8 22.5 35.2 24.7 3.1 19.2 18.3 24.1 26.9 19.6 23.0 29.8 47.0 23.4 28.1 16.3 25.9 24.6 25.7 19.3 65.8 10.1 24.1 24.2 22.4 30.7 32.8 3.0 19.3 34.2 21.4 7.5 28.4 31.0 32.0 16.6 17.0 20.0 30.6 21.4 26.2 10.9 42.2 39.7 25.5 51.5 13.1 24.6 23.9 7.8 16.9 22.0 11.5 46.1 26.8 37.3 31.6 17.4 P2RX5 "LRH-1, P2X5" ENSG00000083454 "Purinergic receptor P2X 5" Q93086 17 3672199-3696240 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.7;lymphoid tissue: 78.2" "Group enriched" "Detected in some" 4 "B-cells: 94.6;Plasma cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "memory B-cell: 76.4;naive B-cell: 84.8" "Lineage enriched" "Detected in many" 20 "B-cells: 84.8" "Cell line enhanced" "Detected in many" "Daudi: 53.2;Karpas-707: 32.7;RPMI-8226: 59.5;U-698: 47.1" "HPA021948, HPA067827" Supported Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA021948: AB_1854878, HPA067827: AB_2685908" "unprognostic (1.08e-3)" "unprognostic (9.16e-2)" "unprognostic (1.40e-2)" "unprognostic (5.81e-2)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (8.33e-2)" "unprognostic (4.34e-1)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.99e-8)" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (3.50e-2)" "unprognostic (3.63e-2)" 0.8 0.3 1.8 30.4 2.2 9.4 0.8 0.2 2.7 0.3 0.0 2.4 1.5 0.1 0.0 0.7 0.3 1.3 8.0 2.1 0.9 0.7 0.5 1.4 78.2 0.6 0.5 0.0 0.2 0.2 1.2 0.2 0.7 0.5 1.9 0.4 1.8 0.0 17.5 0.0 24.7 0.5 0.1 54.4 3.4 0.7 1.1 12.1 0.9 4.0 53.9 2.7 0.3 1.4 8.3 6.7 0.0 0.0 0.2 1.3 0.0 8.4 3.9 0.9 2.6 5.5 9.8 53.2 4.9 4.2 2.9 4.3 18.8 0.0 1.7 0.9 3.2 2.7 17.5 6.3 1.2 3.6 4.2 2.1 1.8 0.2 12.4 6.5 0.0 12.2 0.5 32.7 18.2 0.0 23.4 8.1 4.9 4.4 20.5 0.8 0.0 59.5 0.2 6.3 4.3 0.0 7.5 2.5 3.9 0.0 2.0 3.3 0.1 0.0 4.5 0.2 1.5 11.0 25.2 47.1 0.0 5.1 0.5 0.0 0.1 2.0 3.1 0.0 4.2 76.4 2.8 2.2 0.4 84.8 0.3 0.3 0.0 0.0 0.0 0.1 1.9 4.5 1.8 2.2 0.2 2.7 2.1 0.9 0.6 0.5 0.7 0.1 1.1 1.4 0.1 0.0 0.6 0.0 94.6 0.4 0.1 0.0 0.0 0.8 0.1 0.1 2.7 0.0 0.0 1.8 0.0 0.0 13.4 0.0 0.0 0.2 4.8 0.2 0.2 0.7 0.0 11.1 0.0 0.2 0.0 0.3 0.5 0.3 4.5 0.0 1.4 0.4 0.2 0.0 0.0 0.1 0.0 1.2 0.0 3.1 1.5 1.6 3.6 0.0 1.1 0.0 2.1 0.0 0.0 1.5 0.0 0.0 29.7 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.9 1.0 0.8 0.0 0.0 0.0 11.0 0.0 0.1 0.1 PARP15 "ARTD7, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 23.1;intestine: 42.1;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 19.2;B-cells: 88.4;dendritic cells: 38.6;granulocytes: 19.6;NK-cells: 21.6;Plasma cells: 18.6;T-cells: 31.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.6;JURKAT: 5.1;REH: 3.5;THP-1: 3.7;TIME: 8.9" "Low region specificity" "Detected in single" HPA035757 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 3.7 1.2 3.1 25.7 2.7 23.1 1.8 4.2 3.8 1.7 1.2 3.8 2.6 1.9 1.3 2.0 2.0 4.4 1.7 2.1 1.2 1.7 3.2 9.0 44.4 1.8 2.3 0.7 0.8 0.2 0.7 2.5 1.7 1.8 4.8 2.2 2.2 1.1 6.0 1.2 42.1 1.9 0.7 67.2 4.1 2.5 2.0 8.3 3.0 1.9 50.3 4.5 1.6 3.6 0.3 0.2 0.3 0.3 0.1 0.2 0.3 0.2 0.1 0.0 0.0 0.2 0.7 0.3 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.7 0.1 7.6 0.5 0.3 0.1 0.5 0.3 1.5 0.1 0.3 0.1 0.2 1.7 5.1 0.2 1.3 0.0 0.3 2.3 0.4 0.4 0.1 0.1 3.5 0.2 0.3 0.0 0.6 0.5 0.3 0.1 0.1 0.1 0.3 0.5 3.7 8.9 0.2 0.6 0.3 0.2 0.6 0.4 1.6 0.4 0.2 0.1 1.8 0.2 0.1 7.2 0.3 5.8 9.4 4.4 5.4 0.8 9.3 3.8 4.8 0.5 3.9 0.7 1.0 4.2 2.2 3.1 2.7 4.2 3.8 2.1 1.2 1.8 2.3 1.7 0.7 2.0 3.6 0.8 19.2 15.9 0.0 88.4 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 2.1 0.0 0.0 0.1 38.6 0.1 0.0 0.0 0.2 0.3 0.1 1.2 0.0 7.4 0.1 0.0 0.1 2.7 2.6 0.3 19.6 0.0 2.2 0.6 8.3 0.0 0.2 0.0 0.0 5.1 1.4 0.2 0.0 6.4 1.8 6.5 4.7 0.0 21.6 0.0 0.1 0.1 0.0 0.0 18.6 0.0 0.0 0.1 10.5 0.0 0.0 0.7 0.4 0.1 1.6 0.4 0.0 0.3 31.1 0.0 0.0 0.0 PARVG ENSG00000138964 "Parvin gamma" Q9HBI0 22 44172956-44219533 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.7;lymphoid tissue: 30.1" "Cell type enhanced" "Detected in many" "B-cells: 56.9;dendritic cells: 51.7;granulocytes: 60.1;Hofbauer cells: 66.7;Kupffer cells: 87.3;Langerhans cells: 53.4;Macrophages: 91.9;monocytes: 62.0;T-cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HL-60: 116.4;NB-4: 44.9;THP-1: 64.7;U-937: 53.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031833, HPA031834" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "HPA031833: AB_2674063, HPA031834: AB_10601242" "unprognostic (9.83e-3)" "unprognostic (2.30e-2)" "unprognostic (2.06e-1)" "prognostic favorable (4.44e-6)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (3.19e-2)" "unprognostic (7.02e-2)" "unprognostic (2.17e-1)" "unprognostic (3.87e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (3.73e-1)" "unprognostic (1.35e-2)" "unprognostic (1.09e-1)" "unprognostic (9.89e-2)" 3.5 2.9 3.7 26.7 3.5 49.7 1.8 4.4 7.1 2.6 4.0 3.1 3.6 2.4 0.6 2.5 2.2 6.2 1.3 3.8 4.7 1.8 3.1 10.4 30.1 8.2 4.9 0.8 1.4 0.5 1.3 3.0 6.9 2.1 3.4 0.2 2.6 1.1 1.2 1.7 12.7 2.9 5.9 28.9 4.4 1.7 7.9 18.4 1.9 0.4 26.8 4.7 1.5 9.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.8 0.0 0.0 0.0 116.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 16.8 44.9 0.1 0.0 0.0 9.2 0.2 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 64.7 0.0 0.0 11.5 0.2 0.0 0.3 0.0 0.3 0.0 53.9 1.9 12.5 62.0 71.3 13.9 57.6 13.9 21.4 8.0 15.2 49.2 20.4 8.9 10.3 72.2 13.1 65.9 33.3 12.1 44.6 3.7 3.5 4.4 7.1 3.8 4.7 8.2 4.9 6.9 5.9 7.9 9.4 1.3 6.4 14.0 1.0 56.9 2.4 0.1 0.0 0.6 0.2 0.7 1.5 1.1 0.0 3.1 0.0 0.0 0.6 51.7 0.1 0.0 0.0 4.2 3.7 0.4 2.9 0.0 10.1 3.9 0.2 0.7 2.3 3.6 2.5 60.1 0.0 3.9 1.3 66.7 0.0 2.9 0.0 0.0 87.3 53.4 2.7 0.0 91.9 5.4 10.3 62.0 0.0 26.8 0.0 1.4 0.0 0.0 0.0 15.9 0.0 0.0 0.5 1.5 0.2 0.0 0.5 0.4 1.1 0.8 0.4 1.8 1.0 48.3 0.0 0.1 0.1 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 29 "B-cells: 91.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 9 "Daudi: 66.6;REH: 194.1;U-698: 87.1" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.3 0.1 0.4 14.9 0.3 9.4 0.1 0.5 0.5 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.8 0.2 0.3 0.6 0.1 0.2 0.3 39.7 1.1 6.5 0.0 0.0 0.0 0.2 0.1 4.1 0.3 0.8 0.5 1.0 0.0 3.1 0.0 6.6 0.0 0.8 18.7 1.6 0.6 1.9 2.8 0.2 0.0 36.2 1.1 0.0 0.3 0.1 0.3 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 66.6 0.1 0.0 0.1 0.2 0.1 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.1 0.3 1.9 0.3 0.4 194.1 0.4 0.3 0.0 0.0 13.2 2.9 0.1 0.7 0.0 0.0 0.0 7.5 0.2 0.0 0.2 0.1 0.0 0.2 0.1 87.1 0.0 1.5 0.1 0.7 0.0 0.1 0.0 0.1 0.1 39.0 0.0 0.0 0.1 26.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.7 0.4 0.3 0.5 0.5 0.3 0.6 1.1 6.5 4.1 0.8 1.9 0.3 0.0 0.0 0.0 0.7 91.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.3 0.0 3.1 0.0 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.0 0.1 0.0 2.7 0.4 0.0 0.1 0.0 0.1 0.0 0.8 0.1 0.6 0.2 0.2 0.0 0.0 2.0 0.0 0.0 0.3 PIGB ENSG00000069943 "Phosphatidylinositol glycan anchor biosynthesis class B" Q92521 15 55318960-55355648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039929 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "HPA039929: AB_10673539" "unprognostic (1.91e-2)" "unprognostic (7.45e-2)" "unprognostic (3.00e-1)" "unprognostic (2.03e-2)" "unprognostic (2.96e-2)" "unprognostic (4.65e-2)" "unprognostic (2.04e-1)" "unprognostic (3.37e-3)" "unprognostic (7.52e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (4.24e-2)" 6.4 4.8 2.3 5.8 2.6 9.1 9.0 2.8 2.6 5.5 3.1 7.0 7.5 6.4 11.0 5.7 7.8 6.3 2.8 2.5 3.3 10.3 9.4 6.3 8.2 2.8 2.7 4.7 5.7 10.6 3.9 4.8 2.6 7.7 7.8 7.9 4.3 6.8 1.5 6.1 5.8 5.6 2.7 6.1 7.6 6.5 2.7 6.3 13.3 1.8 8.6 7.5 3.7 3.1 10.5 12.2 5.8 4.1 6.6 13.2 7.8 9.0 19.9 10.4 17.8 5.1 10.3 10.9 10.4 12.9 15.6 18.3 3.3 9.5 8.6 10.4 6.4 10.9 13.6 6.7 11.9 30.8 8.7 12.5 11.4 7.9 10.7 13.8 13.6 9.2 12.2 6.9 15.0 9.1 3.4 12.8 3.1 7.9 4.8 4.9 5.6 24.1 18.4 12.4 2.5 6.2 8.1 12.2 17.3 5.4 11.7 22.2 9.5 13.6 4.3 3.7 18.6 8.1 15.9 8.6 12.4 34.5 10.2 13.6 7.7 3.3 6.2 9.7 7.0 6.0 6.1 6.9 7.0 3.9 4.8 5.5 14.5 5.3 11.4 5.4 6.5 5.5 2.3 2.6 2.8 2.6 2.5 3.3 2.8 2.7 2.6 2.7 2.7 3.1 3.5 9.6 9.5 17.6 27.5 4.6 9.5 14.9 4.6 3.3 5.6 4.2 3.4 1.5 14.9 0.0 12.5 12.4 11.2 4.8 1.9 7.4 26.8 4.3 3.2 4.7 6.6 8.2 18.3 10.9 12.0 6.0 6.1 6.4 8.2 4.6 6.8 4.4 8.6 1.7 17.7 4.1 4.1 7.5 6.7 5.1 1.5 8.8 3.6 12.2 8.4 2.7 11.3 17.1 14.6 6.9 4.0 1.5 3.8 3.4 6.4 9.7 7.9 9.4 6.6 4.8 4.2 5.9 3.8 5.7 4.0 6.6 12.5 4.2 4.0 7.4 PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 83.2;lymphoid tissue: 62.3;salivary gland: 73.6" "Cell type enhanced" "Detected in many" "B-cells: 53.7;Hepatocytes: 70.7;Kupffer cells: 127.0;Macrophages: 89.8;Microglial cells: 60.9;monocytes: 57.4;NK-cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.7;memory B-cell: 48.3;naive B-cell: 44.5;non-classical monocyte: 123.0" "Group enriched" "Detected in all" 6 "B-cells: 48.3;monocytes: 123.0" "Cell line enhanced" "Detected in many" "Daudi: 85.3;NB-4: 62.1;REH: 183.5;THP-1: 92.9;U-698: 114.7;U-937: 95.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" Cytosol "Nucleoplasm, Plasma membrane" "CAB026136: , HPA038452: AB_2676019" "unprognostic (2.83e-2)" "unprognostic (4.61e-3)" "unprognostic (7.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (4.69e-2)" "unprognostic (5.45e-1)" "unprognostic (1.13e-1)" 8.1 4.5 2.1 51.1 2.0 47.5 4.7 2.4 3.2 2.8 2.7 7.3 6.8 2.1 1.7 2.4 2.2 24.8 2.5 1.9 2.9 11.8 83.2 16.7 61.2 6.5 4.6 6.0 22.8 2.0 1.4 14.1 5.3 2.8 8.6 3.1 73.6 2.4 0.7 1.0 7.7 8.3 4.7 62.3 6.9 3.0 5.7 8.7 4.1 3.1 57.8 15.2 0.6 7.6 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.9 1.2 2.8 1.5 85.3 8.5 0.0 1.3 0.1 17.7 0.0 0.6 48.0 3.0 13.0 0.0 1.7 0.1 36.1 6.7 0.0 0.0 0.1 0.0 0.1 0.0 3.1 0.9 0.1 0.1 0.4 1.1 62.1 0.8 24.3 1.0 183.5 4.3 20.0 0.2 0.1 3.6 2.0 0.2 0.2 1.1 0.3 0.2 92.9 0.0 0.0 2.8 0.1 0.7 0.7 0.2 114.7 0.0 95.2 0.0 6.1 16.0 10.5 13.3 44.7 4.7 48.3 0.3 4.1 12.9 44.5 0.1 3.3 13.5 14.0 123.0 11.3 0.5 14.4 2.1 2.0 2.4 3.2 1.9 2.9 6.5 4.6 5.3 4.7 5.7 7.6 0.5 3.2 3.9 1.3 53.7 1.5 0.1 0.1 0.6 0.6 2.2 2.3 2.6 32.9 2.2 1.8 2.1 0.5 41.5 8.1 1.9 40.0 4.3 0.3 0.1 1.8 1.8 10.3 0.8 29.1 0.9 0.7 0.0 0.2 14.0 0.2 5.7 70.7 47.7 0.0 0.8 2.8 4.1 127.0 32.5 1.0 1.2 89.8 5.4 60.9 57.4 0.2 58.7 1.0 0.3 16.4 21.2 2.2 9.4 0.4 1.6 18.3 1.1 3.4 0.0 0.6 0.8 0.8 0.2 0.3 1.1 2.3 18.3 0.4 3.8 0.3 PIKFYVE "FAB1, KIAA0981, MGC40423, p235, PIP5K, PIP5K3, ZFYVE29" ENSG00000115020 "Phosphoinositide kinase, FYVE-type zinc finger containing" Q9Y2I7 2 208266255-208358746 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 82.0;Oligodendrocyte precursor cells: 80.9;Oligodendrocytes: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042604 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "HPA042604: AB_10796580" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.88e-1)" "unprognostic (3.03e-1)" "unprognostic (2.04e-2)" "prognostic favorable (6.81e-4)" "unprognostic (6.82e-3)" "unprognostic (6.45e-2)" "unprognostic (1.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" 10.4 7.9 7.6 12.0 7.6 28.8 8.1 14.3 9.3 9.1 10.5 6.1 6.0 9.3 11.9 6.3 6.4 7.2 7.4 7.7 7.3 10.6 10.5 7.8 17.4 8.0 7.4 10.0 22.2 11.1 6.0 9.7 6.9 11.5 7.4 17.3 6.5 8.0 6.5 8.2 7.3 8.9 7.4 15.1 8.0 14.0 8.9 19.3 12.2 9.0 16.1 8.2 5.8 11.1 8.0 7.9 18.3 14.3 18.1 21.4 8.5 9.6 19.5 11.1 15.0 11.3 6.6 9.2 9.8 16.6 21.7 8.0 16.1 10.8 18.8 7.9 10.1 33.0 15.6 10.2 13.7 29.5 28.5 16.0 11.5 13.0 24.1 18.5 18.3 24.1 22.7 16.1 14.0 3.4 26.9 22.1 15.2 6.1 5.9 9.9 14.2 12.7 14.2 11.5 5.8 13.8 10.6 6.8 19.2 21.4 4.3 31.3 21.2 13.8 9.2 9.4 9.0 11.2 14.2 19.2 11.1 25.2 13.9 0.9 0.5 0.4 0.9 0.4 0.5 4.4 1.2 1.4 0.5 3.2 0.9 1.1 0.7 3.2 0.7 1.2 0.9 0.3 7.6 7.6 14.3 9.3 7.7 7.3 8.0 7.4 6.9 7.4 8.9 11.1 18.8 25.6 16.2 58.8 82.0 15.3 6.7 7.8 25.6 21.9 10.5 6.6 17.5 11.5 10.6 11.0 16.7 8.1 14.4 8.1 5.9 5.4 10.4 11.3 19.4 18.8 18.6 25.5 72.6 4.3 5.7 15.7 16.3 21.7 36.1 18.0 18.2 19.4 14.4 10.1 67.9 9.6 4.1 29.9 32.5 8.3 18.6 28.5 10.6 48.7 19.1 13.5 16.5 80.9 81.7 8.5 5.9 13.5 10.3 18.1 14.3 9.9 9.2 19.7 13.1 15.4 18.9 30.5 23.0 14.8 15.3 7.3 21.5 13.3 8.8 11.4 PLEKHF2 "FLJ13187, PHAFIN2, ZFYVE18" ENSG00000175895 "Pleckstrin homology and FYVE domain containing 2" Q9H8W4 8 95133785-95156685 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 102.6;U-698: 109.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024829 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA024829: AB_10603127" "unprognostic (4.08e-2)" "unprognostic (2.98e-2)" "unprognostic (5.72e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.67e-2)" "unprognostic (4.83e-2)" "unprognostic (1.19e-1)" "unprognostic (2.67e-1)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (5.94e-2)" "prognostic favorable (1.49e-4)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (4.61e-3)" 12.4 6.1 5.5 21.3 5.5 84.8 21.6 6.1 6.7 9.2 6.9 16.0 12.6 7.4 14.6 15.4 8.9 11.2 8.9 5.2 5.7 22.2 14.7 17.5 53.1 6.3 5.8 7.3 11.8 6.9 3.6 15.1 6.2 9.3 13.9 14.8 11.8 7.4 10.7 19.5 13.7 7.1 6.6 22.6 21.9 12.3 5.4 23.8 9.7 9.3 56.1 12.7 7.5 8.3 27.5 4.5 7.0 4.2 10.0 11.1 37.6 14.9 20.0 12.7 13.6 11.3 29.7 102.6 12.6 10.5 6.6 33.1 10.9 18.1 18.3 19.2 7.4 49.4 10.0 8.8 9.9 9.9 68.7 7.1 25.0 10.0 18.8 14.9 14.1 32.9 32.6 13.0 13.6 16.8 29.0 12.8 4.2 50.1 20.6 11.5 7.1 14.0 10.4 24.2 9.3 5.4 11.3 13.5 27.8 9.7 36.2 16.0 9.0 9.8 6.7 8.6 8.7 17.2 14.9 109.4 7.5 22.8 14.1 107.2 21.6 43.0 9.0 18.6 10.8 69.7 11.2 13.9 24.3 78.6 12.9 12.7 29.8 12.4 16.0 10.1 13.7 19.4 5.5 5.5 6.1 6.7 5.2 5.7 6.3 5.8 6.2 6.6 5.4 8.3 29.3 12.8 14.1 7.2 88.8 61.4 73.4 29.7 56.3 17.0 49.0 22.7 7.0 31.5 26.1 5.5 14.6 51.6 17.8 46.7 29.4 13.6 59.5 47.1 12.0 18.5 33.6 34.5 5.0 22.0 36.1 11.9 31.1 59.5 60.4 14.4 25.0 11.0 29.6 6.7 2.4 14.6 57.0 22.6 54.0 19.8 8.7 34.7 21.4 14.0 31.9 19.1 13.4 10.6 4.7 14.6 39.0 3.8 21.3 42.4 20.7 95.9 26.2 31.7 13.1 10.8 14.5 55.2 16.0 47.2 57.7 50.9 27.4 6.0 17.7 75.4 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;fallopian tube: 18.2;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 61.5;dendritic cells: 12.6;Inhibitory neurons: 23.3;Melanocytes: 14.2;Plasma cells: 80.4" "Cancer enriched" "Detected in many" 8 "ovarian cancer: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 231.2;naive B-cell: 260.3;plasmacytoid DC: 194.0" "Group enriched" "Detected in many" 20 "B-cells: 260.3;dendritic cells: 194.0" "Group enriched" "Detected in some" 6 "Daudi: 38.3;Karpas-707: 29.2;RPMI-8226: 11.2;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced "Secreted to blood" NA NA 12300 "Cluster 19: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA044507: AB_10795043, HPA056724: AB_2683216" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.94e-6)" "unprognostic (3.71e-2)" "unprognostic (5.16e-5)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (7.81e-4)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" "unprognostic (7.57e-9)" "unprognostic (2.19e-2)" "unprognostic (5.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-1)" 0.2 0.8 5.4 9.9 5.1 2.7 0.6 1.3 10.8 0.2 1.3 2.9 4.3 0.1 0.0 0.6 18.2 1.1 0.1 2.9 9.9 0.7 0.2 1.0 25.1 10.4 6.3 0.4 0.0 0.0 0.0 0.0 9.9 0.2 1.5 0.0 1.6 0.1 0.0 0.1 5.8 0.5 14.3 14.4 3.2 0.6 4.3 2.7 0.4 0.0 23.6 3.7 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 4.0 4.4 23.0 0.1 0.1 0.0 0.2 11.5 2.3 0.2 7.7 0.1 231.2 0.2 0.1 1.1 260.3 0.1 0.1 1.3 1.2 3.2 194.0 0.5 11.1 5.4 5.1 1.3 10.8 2.9 9.9 10.4 6.3 9.9 14.3 4.3 3.0 0.1 0.0 1.9 1.3 61.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.4 0.4 0.2 0.0 23.3 0.1 0.0 0.0 0.3 2.8 0.3 1.7 14.2 1.0 3.0 0.0 1.0 0.0 0.9 0.1 0.0 0.0 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 1.1 0.0 0.3 0.5 POLH "RAD30A, XP-V" ENSG00000170734 "DNA polymerase eta" Q9Y253 6 43576185-43620523 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 91.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006721, HPA026762" Approved Enhanced Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA006721: AB_1847785, HPA026762: AB_10601248" "unprognostic (1.79e-1)" "unprognostic (7.29e-2)" "unprognostic (2.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.61e-1)" "unprognostic (5.11e-3)" "unprognostic (9.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (7.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.24e-1)" "unprognostic (9.50e-2)" "unprognostic (6.73e-2)" "unprognostic (8.77e-2)" "unprognostic (7.91e-2)" "unprognostic (6.02e-2)" 5.0 3.8 2.3 6.9 2.7 4.2 4.8 5.1 2.9 5.9 5.3 7.0 4.6 4.2 3.6 5.5 5.5 4.3 3.7 2.2 2.2 4.7 5.6 5.7 12.9 2.7 2.2 4.7 5.4 3.7 3.2 4.0 2.7 4.7 7.2 7.4 4.0 3.8 8.5 8.5 4.4 6.3 1.8 5.6 4.6 10.6 2.5 12.9 6.8 4.7 14.2 4.8 4.3 3.6 46.7 9.7 13.5 19.9 17.6 29.1 33.0 48.6 13.9 26.2 29.2 12.0 7.9 48.9 12.0 17.6 7.6 11.4 13.1 28.6 31.5 25.9 10.0 15.3 31.6 35.5 13.4 26.8 19.2 19.5 33.4 21.5 11.3 10.6 24.3 14.5 24.0 29.6 33.0 15.0 23.9 6.4 4.2 33.2 7.2 25.1 14.3 11.8 9.9 34.6 15.1 5.4 14.5 12.9 7.3 15.4 17.9 10.8 36.2 23.6 24.4 12.2 25.2 28.0 21.3 91.1 11.8 14.5 27.3 4.1 1.7 2.7 4.2 1.6 3.8 5.0 3.5 3.1 1.3 4.9 2.8 3.0 1.7 4.2 1.6 2.6 4.6 2.0 2.3 2.7 5.1 2.9 2.2 2.2 2.7 2.2 2.7 1.8 2.5 3.6 3.1 12.8 8.2 12.1 15.1 4.7 3.2 4.8 19.4 6.3 3.4 3.3 2.3 5.7 6.5 3.7 10.4 2.4 5.2 6.3 5.9 2.1 11.4 10.2 4.8 2.8 5.4 5.7 14.8 0.9 2.8 5.3 8.2 9.0 0.0 6.1 1.4 2.4 1.7 0.0 15.3 2.2 4.1 2.2 2.2 7.3 3.4 3.0 1.8 6.5 3.2 2.6 2.1 10.1 13.4 1.9 4.5 3.0 12.7 2.2 3.1 2.3 5.4 9.4 0.0 7.0 5.0 25.9 6.7 13.0 3.0 1.9 8.8 5.6 3.0 2.3 POU2F2 "OCT2, OTF2" ENSG00000028277 "POU class 2 homeobox 2" P09086 19 42086110-42196585 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.1" "Cell type enhanced" "Detected in many" "B-cells: 225.5;Kupffer cells: 119.6;Langerhans cells: 104.4;Macrophages: 105.0;monocytes: 137.6;Plasma cells: 96.7;Spermatocytes: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 94.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 52.3;Daudi: 113.0;hTEC/SVTERT24-B: 42.7;U-266/70: 75.5;U-266/84: 80.2;U-698: 88.4;U-87 MG: 41.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002513, HPA049056, HPA062096, HPA064404, HPA073998" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB002513: AB_442118, HPA049056: AB_2732550, HPA062096: AB_2684681, HPA064404: AB_2685259, HPA073998: " "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-2)" "unprognostic (8.89e-2)" "unprognostic (6.77e-2)" "unprognostic (1.44e-2)" "unprognostic (1.62e-2)" "unprognostic (3.34e-1)" "unprognostic (8.39e-2)" "unprognostic (2.09e-1)" "unprognostic (1.52e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (7.57e-11)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (2.61e-2)" "unprognostic (1.54e-1)" 2.6 2.8 6.1 28.0 5.9 8.4 1.7 15.5 10.6 1.1 3.8 4.3 3.1 1.2 1.5 2.0 1.6 3.4 0.8 5.8 15.4 1.4 2.0 3.8 52.1 8.0 9.1 0.8 1.7 0.3 2.0 3.8 9.4 3.0 3.0 1.9 2.6 3.1 1.1 1.4 14.0 2.9 5.8 27.5 5.0 9.2 14.0 6.5 1.5 0.5 48.3 7.1 1.2 6.7 0.9 1.5 1.8 0.1 0.0 2.9 0.5 8.2 52.3 5.1 10.0 0.5 1.4 113.0 2.8 2.9 0.9 1.0 0.6 8.6 23.2 0.3 0.5 2.7 0.3 0.1 0.6 1.1 2.2 2.2 1.6 42.7 2.8 0.4 3.2 2.4 1.3 25.4 1.1 0.8 0.3 6.1 0.4 0.2 0.6 1.3 0.2 0.4 0.2 0.5 1.8 0.8 0.4 0.7 0.8 0.7 0.1 14.1 3.9 22.0 2.3 0.2 1.1 75.5 80.2 88.4 41.3 2.8 3.1 2.6 28.3 0.5 3.1 51.5 2.7 29.3 4.4 4.0 20.9 33.0 2.3 3.3 4.3 1.7 94.9 3.4 7.2 14.4 6.1 5.9 15.5 10.6 5.8 15.4 8.0 9.1 9.4 5.8 14.0 6.7 2.7 0.0 7.0 0.7 225.5 7.8 8.3 14.1 4.6 63.5 7.2 7.6 3.7 2.8 3.2 0.0 6.2 0.9 29.3 2.8 0.0 1.4 15.2 4.0 1.1 7.3 9.5 10.7 19.7 2.8 0.8 2.7 1.5 8.5 6.3 0.5 4.2 1.1 49.5 1.7 10.0 1.6 4.1 119.6 104.4 9.8 0.9 105.0 8.8 32.8 137.6 1.9 37.0 4.5 1.0 3.5 0.1 0.4 96.7 3.8 2.8 0.4 2.4 6.6 0.0 1.7 5.0 75.1 28.8 13.3 8.8 3.7 31.7 0.6 1.0 5.0 PPP1R9B "PPP1R6, PPP1R9, SPINO, Spn" ENSG00000108819 "Protein phosphatase 1 regulatory subunit 9B" Q96SB3 17 50133737-50150677 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 96.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022461 Approved NA NA 420000000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "CAB022461: " "unprognostic (4.71e-1)" "unprognostic (3.77e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.74e-3)" "unprognostic (1.99e-1)" "unprognostic (4.09e-2)" "unprognostic (2.80e-1)" "prognostic favorable (3.11e-4)" "unprognostic (8.50e-2)" "unprognostic (1.57e-2)" "unprognostic (1.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "unprognostic (4.29e-1)" 23.5 30.0 61.4 28.6 58.6 33.7 20.2 39.3 96.7 25.4 4.6 17.6 14.9 22.0 8.4 28.9 19.6 15.5 24.3 90.2 30.3 23.3 11.9 39.9 36.8 25.7 40.1 27.8 18.3 15.2 20.6 14.6 24.0 21.5 8.9 7.9 17.6 10.6 11.8 24.2 30.2 11.8 22.2 52.4 17.8 24.0 47.7 22.5 22.0 14.8 28.0 20.4 22.6 48.9 25.9 45.2 24.0 60.5 31.2 19.8 56.9 36.4 33.1 31.5 22.9 38.3 19.9 48.6 57.8 42.2 30.7 25.2 24.9 25.8 19.6 125.7 37.2 79.9 35.4 26.2 30.3 35.1 121.2 22.2 44.4 34.6 21.7 60.5 31.2 15.4 43.0 35.7 21.0 47.7 13.0 50.2 9.4 33.0 40.9 26.5 32.5 34.6 21.6 15.0 15.1 44.5 23.0 35.6 29.5 19.3 47.7 68.8 25.5 66.4 48.7 46.0 48.8 65.4 16.2 35.2 30.5 34.8 32.4 4.2 1.8 2.9 1.3 1.6 1.1 1.6 1.0 0.9 1.4 2.0 0.4 0.9 4.1 2.2 2.0 2.0 0.5 0.8 61.4 58.6 39.3 96.7 90.2 30.3 25.7 40.1 24.0 22.2 47.7 48.9 18.1 0.0 2.2 6.2 23.6 23.6 3.6 5.8 13.6 18.8 7.8 5.3 7.7 4.3 3.2 16.5 2.1 2.3 29.0 10.9 5.9 9.7 2.6 4.0 9.5 20.9 12.0 20.2 6.6 9.1 3.5 10.5 5.6 6.3 2.5 9.6 18.2 8.7 27.7 16.8 6.5 10.8 10.2 48.6 34.6 5.1 20.2 30.2 12.4 2.8 42.1 3.2 34.0 2.5 2.7 9.1 10.2 15.4 15.4 7.8 18.1 9.8 3.4 2.6 13.1 7.0 9.1 5.5 5.7 16.9 22.4 1.0 14.9 10.0 10.7 5.4 PRDM2 "HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2" ENSG00000116731 "PR/SET domain 2" Q13029 1 13700198-13825079 "Enzymes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005809 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Golgi apparatus" "HPA005809: AB_1079673" "unprognostic (2.22e-1)" "unprognostic (3.28e-1)" "unprognostic (5.34e-2)" "unprognostic (1.28e-2)" "unprognostic (6.70e-2)" "unprognostic (2.72e-3)" "unprognostic (1.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.20e-2)" "unprognostic (2.53e-2)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (9.63e-3)" "unprognostic (3.81e-1)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (5.85e-3)" 21.7 15.2 19.4 19.3 21.2 79.4 21.9 27.5 38.7 27.8 7.6 27.1 13.0 24.2 16.4 21.9 20.9 17.0 19.9 21.5 18.2 14.2 13.1 21.4 27.3 18.5 16.6 34.3 14.9 14.7 16.3 16.7 18.7 24.3 13.8 18.1 21.2 17.6 43.8 27.2 23.6 15.0 12.9 20.2 19.2 18.7 16.9 22.6 24.3 30.0 25.0 27.0 26.8 34.7 15.3 8.5 30.3 11.8 23.5 18.0 14.6 19.5 11.8 13.0 14.5 13.5 16.9 46.4 16.7 18.9 11.0 18.5 22.8 11.4 14.4 28.9 16.3 31.2 10.6 6.4 12.9 10.5 25.8 19.1 19.7 13.8 11.4 12.4 13.0 18.0 28.2 52.0 16.5 7.7 16.9 16.6 9.0 12.1 11.4 23.3 16.4 13.9 7.4 17.0 26.3 17.0 15.7 9.8 21.4 18.0 13.9 16.8 23.2 16.7 18.1 15.3 10.9 75.8 55.4 65.5 14.8 24.1 21.9 4.7 4.9 7.5 5.5 3.2 3.5 18.5 4.4 5.2 3.0 13.4 4.9 4.4 9.9 6.2 6.0 5.6 4.4 2.8 19.4 21.2 27.5 38.7 21.5 18.2 18.5 16.6 18.7 12.9 16.9 34.7 41.3 38.5 39.7 34.3 182.9 62.1 54.8 17.1 61.5 49.5 43.8 33.8 41.3 27.1 33.0 23.9 45.9 25.6 77.7 26.9 17.6 17.3 21.7 84.5 62.5 35.1 37.8 21.7 114.5 13.8 16.2 47.6 25.5 121.2 40.5 50.0 26.0 18.8 16.6 70.7 97.0 24.1 14.2 45.6 39.9 15.6 44.1 42.1 30.2 75.9 41.5 21.2 59.8 70.4 122.5 15.5 25.7 45.1 71.7 54.5 34.2 9.0 43.8 39.7 26.3 86.3 34.4 52.7 49.4 65.4 52.1 18.3 74.4 25.8 19.6 64.5 PRDM4 PFM1 ENSG00000110851 "PR/SET domain 4" Q9UKN5 12 107732871-107761272 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024322, HPA067437" Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA024322: AB_1855691, HPA067437: AB_2685839" "unprognostic (4.64e-2)" "unprognostic (3.16e-3)" "unprognostic (1.73e-3)" "unprognostic (2.35e-1)" "unprognostic (1.94e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.86e-4)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.66e-4)" "unprognostic (9.64e-2)" "unprognostic (9.06e-3)" "unprognostic (5.31e-2)" "prognostic favorable (3.15e-7)" "unprognostic (9.24e-2)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (2.62e-3)" 12.8 8.6 12.8 11.9 13.3 16.9 11.7 14.5 13.5 12.0 13.1 15.0 13.2 15.2 13.4 15.6 11.8 11.2 8.9 12.3 12.8 21.0 7.0 12.9 12.4 13.2 12.8 15.0 10.2 44.5 8.1 12.5 13.5 11.5 16.4 20.9 11.5 12.1 12.5 12.3 13.8 13.9 11.1 12.3 12.7 11.6 14.7 11.4 12.6 12.8 14.0 11.5 13.2 14.3 19.2 20.9 22.4 23.4 23.7 24.3 17.1 25.6 33.2 25.4 19.2 14.7 8.1 24.6 10.6 27.2 23.7 13.4 23.5 18.7 27.4 18.1 24.1 19.5 15.5 15.8 30.5 28.1 19.3 29.8 35.3 28.7 49.1 27.6 33.5 22.7 24.0 29.0 30.6 20.1 15.9 24.9 11.7 12.4 28.2 12.8 22.4 24.2 26.2 29.0 27.6 25.8 19.3 13.5 23.5 15.2 16.5 14.1 34.1 19.4 14.0 26.1 21.7 20.3 21.5 17.2 14.2 13.1 14.7 1.1 0.8 1.4 1.9 3.0 1.3 2.6 1.0 1.7 2.3 2.1 1.6 2.0 0.3 1.2 4.2 1.2 2.2 0.8 12.8 13.3 14.5 13.5 12.3 12.8 13.2 12.8 13.5 11.1 14.7 14.3 10.6 9.6 6.4 4.9 38.3 14.5 9.0 4.2 8.0 13.6 7.6 6.7 7.3 4.3 6.3 12.9 14.6 6.3 9.8 13.3 9.8 14.8 23.4 12.3 19.8 11.2 12.6 6.9 12.0 11.4 7.5 9.7 10.2 21.8 3.8 11.0 11.0 4.6 11.4 33.7 12.2 10.3 2.0 10.3 7.2 28.4 6.2 9.0 8.8 15.0 12.1 7.5 12.3 9.5 12.9 16.6 8.1 4.9 8.2 12.4 14.6 9.7 7.2 11.7 6.6 12.4 10.6 6.3 12.5 12.5 16.9 4.8 11.1 6.4 12.0 10.2 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 29.0 11.5 7.2 23.6 7.3 29.4 29.3 5.4 7.7 26.6 12.5 20.3 17.1 21.8 4.7 27.5 24.1 11.2 13.8 6.1 6.0 19.2 13.8 34.3 31.1 10.0 6.3 21.8 19.1 8.3 24.0 11.1 6.8 23.9 7.1 4.4 24.7 10.0 8.0 46.8 29.9 6.0 6.0 54.3 20.3 6.6 7.7 25.6 28.9 4.8 21.2 19.5 26.9 6.6 19.6 34.5 12.8 16.6 7.3 6.4 15.1 11.5 13.2 19.6 19.7 19.7 21.0 22.3 16.3 13.2 13.2 27.5 9.5 26.0 5.9 19.8 17.5 25.9 11.5 10.2 12.8 21.2 34.7 11.0 15.8 12.7 9.8 12.8 30.1 21.5 14.6 35.4 7.0 23.8 32.7 53.1 9.7 27.4 17.4 25.8 5.8 37.5 11.4 32.7 7.7 22.4 18.8 18.8 4.6 10.6 11.6 7.5 17.6 8.7 18.8 7.1 10.0 31.8 149.1 13.5 8.5 17.7 11.0 0.6 0.7 2.6 3.9 0.7 3.3 4.3 3.9 4.3 0.3 4.1 3.3 3.3 5.3 2.2 0.5 0.0 2.9 1.5 7.2 7.3 5.4 7.7 6.1 6.0 10.0 6.3 6.8 6.0 7.7 6.6 37.8 9.6 9.9 5.9 46.5 22.0 32.0 13.2 22.8 6.4 13.9 11.3 17.2 12.8 13.0 9.2 0.0 13.8 17.5 43.6 7.9 18.6 1.2 15.3 6.7 37.2 21.6 4.0 6.5 28.2 13.8 9.6 23.4 15.0 14.5 14.1 37.1 8.5 9.0 1.7 2.8 21.7 4.1 12.3 11.4 3.1 11.8 8.3 12.4 11.2 9.3 6.5 42.2 4.0 3.1 29.5 35.1 6.8 47.0 22.9 34.1 9.3 15.6 4.4 13.1 6.1 7.6 2.9 17.9 21.2 26.7 29.7 31.9 6.6 15.3 30.2 PRR3 "CAT56, Em:AB014077.1, Em:AB023052.2" ENSG00000204576 "Proline rich 3" P79522 6 30557280-30563723 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 16.6;HAP1: 20.1;HEL: 15.1;JURKAT: 14.7;U-266/84: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064061 Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA064061: AB_2685185" "unprognostic (3.76e-2)" "unprognostic (6.72e-3)" "unprognostic (8.90e-2)" "unprognostic (2.10e-3)" "unprognostic (1.92e-3)" "unprognostic (1.39e-1)" "unprognostic (1.65e-3)" "unprognostic (1.25e-2)" "unprognostic (3.73e-2)" "prognostic favorable (6.49e-6)" "prognostic favorable (5.61e-5)" "unprognostic (4.71e-2)" "prognostic unfavorable (7.84e-7)" "unprognostic (2.80e-1)" "unprognostic (2.82e-1)" "unprognostic (3.66e-1)" "unprognostic (1.21e-3)" 3.9 5.3 0.7 0.1 0.7 0.0 3.5 0.7 3.0 6.5 0.6 3.4 0.0 6.9 1.1 2.5 5.9 0.0 3.6 0.7 0.7 3.5 3.1 3.3 0.3 0.7 0.9 10.6 3.2 0.1 5.8 0.0 0.8 4.3 0.2 0.6 2.6 0.2 1.5 3.1 3.6 0.0 0.6 5.0 3.1 4.8 0.7 0.8 3.9 0.0 0.6 4.5 4.1 0.7 0.1 3.9 7.7 16.6 5.2 1.3 0.0 0.0 0.0 0.0 0.0 6.6 0.1 7.0 8.6 2.1 4.4 0.6 20.1 1.5 0.0 4.1 3.7 15.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 5.6 0.0 0.0 0.0 14.7 7.8 0.0 3.6 0.0 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.0 1.7 0.3 0.1 10.6 4.8 0.5 0.0 0.0 0.0 4.3 0.5 6.4 0.1 0.0 0.0 9.2 13.1 8.8 0.0 5.8 3.6 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.2 0.5 0.0 0.1 0.0 0.2 0.0 1.2 0.0 0.1 0.7 0.7 0.7 3.0 0.7 0.7 0.7 0.9 0.8 0.6 0.7 0.7 10.6 9.6 19.1 11.4 18.2 5.7 6.4 8.6 12.5 11.3 11.0 22.9 3.6 11.5 10.7 3.7 14.6 14.2 11.2 14.0 7.9 5.8 0.6 8.7 14.2 8.0 7.8 7.6 18.8 9.5 8.7 10.9 24.5 8.4 12.0 16.3 9.3 5.9 7.9 6.7 16.4 10.2 14.2 6.0 7.9 2.6 10.2 8.8 10.6 9.4 12.7 6.4 12.3 17.1 12.2 5.7 5.7 10.1 14.5 5.7 9.9 9.4 11.3 19.2 6.6 11.9 9.8 10.3 6.6 9.1 5.7 9.9 12.0 15.9 8.3 3.9 PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261902-96336995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 10.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" Nucleoplasm "HPA016852: AB_1855878" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (7.48e-2)" "unprognostic (5.68e-3)" "prognostic unfavorable (1.08e-5)" "prognostic unfavorable (9.83e-4)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-3)" "unprognostic (4.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.55e-2)" 1.6 2.2 1.6 3.4 2.0 4.9 3.1 1.2 2.6 3.5 0.8 3.4 4.1 2.1 2.8 3.7 2.5 3.1 7.2 1.8 1.0 3.7 4.6 2.6 5.6 0.5 0.6 3.6 2.7 8.0 0.6 4.6 1.3 1.9 2.9 0.9 2.0 3.5 2.9 3.2 3.2 3.6 0.2 2.6 1.4 1.9 2.0 3.6 4.5 3.0 5.2 2.6 1.1 1.4 14.9 11.6 2.0 5.5 4.2 8.5 3.4 10.6 15.5 10.6 7.5 4.6 4.2 24.9 9.5 10.5 2.1 6.0 14.1 11.1 16.1 12.5 10.3 24.5 19.8 2.5 4.3 17.8 8.1 7.2 10.9 14.4 10.2 2.7 7.0 7.6 12.5 12.3 9.7 4.4 14.0 3.0 3.1 5.1 11.1 10.9 10.1 18.8 5.7 12.5 8.6 3.5 3.9 3.4 1.4 2.3 8.2 6.3 11.8 9.1 5.5 6.3 12.3 2.5 13.3 11.8 5.7 19.3 7.5 10.5 2.6 1.5 1.7 1.6 2.5 1.7 2.8 2.2 4.0 2.2 2.5 1.8 0.9 3.2 1.7 1.2 1.7 6.7 1.6 2.0 1.2 2.6 1.8 1.0 0.5 0.6 1.3 0.2 2.0 1.4 12.4 19.2 9.1 8.8 50.5 31.6 18.9 22.6 42.7 10.2 22.9 18.4 94.5 14.3 15.6 11.0 10.4 78.4 23.6 11.9 1.9 20.5 60.1 6.6 9.1 22.9 5.4 38.3 29.3 44.9 54.1 18.0 14.8 9.3 32.4 17.6 34.2 32.1 45.9 5.0 29.2 17.1 10.2 45.3 31.5 52.2 23.3 36.0 19.6 15.9 39.3 4.7 29.9 21.1 8.7 23.9 11.9 25.9 45.5 21.4 16.6 19.0 5.2 4.7 0.0 13.8 15.8 12.1 18.8 33.1 33.5 80.9 34.3 14.6 34.8 16.3 PTPN6 "HCP, HCPH, PTP-1C, SHP-1, SHP1" ENSG00000111679 "Protein tyrosine phosphatase non-receptor type 6" P29350 12 6946468-6961316 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 131.8;lymphoid tissue: 153.5" "Cell type enhanced" "Detected in many" "B-cells: 214.6;granulocytes: 137.3;Hofbauer cells: 191.6;Kupffer cells: 146.5;Langerhans cells: 118.2;Macrophages: 152.1;NK-cells: 154.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 170.9;HL-60: 154.3;HMC-1: 648.7;THP-1: 259.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001466, CAB004572, CAB072845" Enhanced Supported Nucleoplasm,Nucleoli NA NA 6000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Nucleoli "CAB004572: AB_628251, CAB072845: , HPA001466: AB_1855930" "unprognostic (4.28e-3)" "prognostic favorable (1.87e-4)" "prognostic unfavorable (5.42e-4)" "prognostic favorable (6.65e-4)" "unprognostic (6.54e-2)" "unprognostic (7.92e-2)" "unprognostic (2.36e-1)" "unprognostic (1.44e-2)" "unprognostic (6.93e-3)" "unprognostic (3.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.60e-3)" "unprognostic (1.98e-3)" "unprognostic (2.60e-2)" "unprognostic (5.91e-2)" "prognostic favorable (2.64e-8)" 14.4 15.6 3.7 102.5 3.9 131.8 11.0 4.3 4.2 11.1 6.0 21.9 30.4 6.2 10.2 12.8 13.9 20.3 4.9 3.6 5.2 12.2 19.3 49.7 153.5 7.0 4.6 2.9 11.9 13.7 10.0 19.8 6.3 11.7 21.3 0.7 17.0 9.0 2.0 18.8 42.0 12.3 5.9 128.0 28.0 3.1 6.3 71.3 12.6 4.5 127.3 27.0 7.5 10.6 16.4 30.8 0.2 0.1 0.1 0.0 28.5 0.0 0.0 0.0 0.0 16.5 36.0 11.9 8.4 0.0 0.0 18.3 0.3 21.6 0.0 7.3 6.5 170.9 3.4 13.9 0.0 154.3 648.7 0.1 15.4 0.0 6.5 0.0 0.0 60.0 0.3 1.3 0.0 34.5 55.4 92.2 8.3 38.0 5.1 50.4 0.2 86.5 16.7 30.2 2.7 0.0 5.2 24.9 0.2 20.9 7.7 259.8 0.4 0.0 0.2 0.1 0.2 0.4 0.2 5.5 0.4 66.3 0.5 676.7 368.3 1112.5 263.4 728.6 169.3 595.0 125.3 195.9 377.0 650.0 142.7 182.6 674.8 238.6 1117.7 98.7 146.8 789.3 3.7 3.9 4.3 4.2 3.6 5.2 7.0 4.6 6.3 5.9 6.3 10.6 10.5 6.4 13.8 0.7 214.6 9.1 8.2 18.8 29.6 0.0 8.6 10.0 2.1 11.5 15.3 5.5 0.0 25.6 77.7 16.0 15.6 15.8 50.4 12.1 1.5 7.5 24.7 22.9 0.9 15.4 18.3 3.0 25.0 11.8 137.3 10.9 8.9 11.6 191.6 0.0 0.9 13.2 18.3 146.5 118.2 10.5 0.9 152.1 14.2 3.7 99.7 0.5 154.5 2.0 0.1 12.6 16.9 0.0 53.5 3.9 22.8 14.3 17.2 0.5 6.6 1.6 4.0 0.3 1.3 14.6 8.7 18.5 86.2 24.5 15.6 7.8 QRSL1 "DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA" ENSG00000130348 "Glutaminyl-tRNA amidotransferase subunit QRSL1" Q9H0R6 6 106629578-106668417 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "memory B-cell: 86.4;naive B-cell: 71.0" "Lineage enriched" "Detected in all" 7 "B-cells: 86.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029585, HPA029587" Approved Approved Vesicles,Centrosome NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Vesicles Centrosome "HPA029585: AB_10599823, HPA029587: AB_10602311" "unprognostic (1.86e-3)" "unprognostic (5.58e-2)" "unprognostic (6.19e-3)" "unprognostic (3.45e-1)" "unprognostic (2.11e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (8.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.03e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.06e-1)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "unprognostic (3.46e-1)" 5.0 5.7 4.0 8.6 5.2 6.4 7.4 4.7 5.0 4.8 5.8 8.2 7.8 6.3 6.1 5.7 5.4 4.8 10.1 4.1 4.5 9.3 7.8 4.6 15.9 4.6 4.5 5.6 6.0 9.4 4.3 5.7 5.0 5.3 9.1 8.4 6.1 5.6 19.4 5.9 8.9 5.8 4.1 10.5 6.7 6.6 4.5 8.2 9.2 21.3 15.5 5.7 4.9 7.4 9.0 9.1 12.3 17.8 7.8 9.7 17.3 10.0 10.2 13.1 13.0 10.7 7.1 29.7 8.9 11.2 13.5 15.5 18.6 12.1 16.4 14.2 14.1 14.5 9.7 11.1 12.2 33.2 12.5 9.6 18.6 14.0 20.6 9.9 9.5 18.4 26.8 9.4 11.0 10.1 10.7 16.1 12.9 15.6 10.5 28.9 15.8 7.5 14.3 10.2 10.7 11.0 8.0 18.4 15.3 10.7 12.1 25.3 9.3 9.2 7.6 10.0 15.7 5.4 8.3 17.2 12.6 22.1 14.0 5.0 6.4 1.0 6.4 9.6 6.3 86.4 7.1 5.6 10.7 71.0 6.6 6.4 1.6 7.0 13.0 8.5 8.5 5.7 4.0 5.2 4.7 5.0 4.1 4.5 4.6 4.5 5.0 4.1 4.5 7.4 9.0 19.2 12.5 20.2 64.6 4.0 8.4 12.8 6.2 14.9 10.3 6.1 24.8 7.2 9.3 11.0 16.7 21.5 12.3 11.0 17.6 15.4 15.5 28.2 12.0 10.8 17.4 13.7 14.6 18.4 23.0 9.9 15.3 14.8 18.9 15.3 8.2 14.6 12.9 3.3 18.9 11.2 14.2 12.4 6.1 8.4 8.4 10.0 8.8 12.2 18.3 9.9 19.6 22.6 26.5 14.2 8.3 9.1 13.2 9.3 12.2 19.5 19.9 19.1 0.0 10.0 10.0 25.6 14.2 12.2 5.4 12.3 14.3 21.1 18.7 8.9 RABEP2 "FLJ23282, FRA" ENSG00000177548 "Rabaptin, RAB GTPase binding effector protein 2" Q9H5N1 16 28904421-28936526 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047641 Approved Supported Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA047641: AB_2680111" "unprognostic (4.93e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-2)" "unprognostic (7.06e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.84e-4)" "unprognostic (2.46e-1)" "unprognostic (1.42e-1)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (1.26e-3)" "unprognostic (5.86e-2)" "prognostic favorable (1.24e-6)" "unprognostic (7.50e-2)" "unprognostic (8.20e-2)" "unprognostic (1.08e-1)" "unprognostic (5.92e-3)" 7.3 21.5 7.3 25.1 8.8 11.5 9.3 8.2 9.2 11.0 10.7 15.0 16.8 8.4 2.7 18.7 7.0 6.6 16.8 6.5 7.9 19.2 10.6 10.1 46.7 10.7 8.5 6.3 17.9 11.5 16.4 5.3 8.4 28.6 4.6 3.5 17.5 7.0 6.5 23.6 28.3 3.4 7.9 47.9 14.4 6.2 8.2 5.3 13.9 3.2 9.4 12.5 12.3 8.5 13.5 21.1 5.6 10.5 3.3 4.7 10.1 15.5 9.2 10.9 10.7 15.9 12.0 27.7 23.7 6.5 4.4 17.8 2.2 9.9 2.1 9.5 9.9 10.5 17.0 21.7 6.5 7.7 32.1 7.9 8.0 13.5 2.4 6.3 15.5 7.4 4.9 9.7 8.5 31.9 9.5 17.8 7.3 5.4 11.4 33.6 5.1 17.4 7.5 17.5 8.6 11.1 7.6 34.8 7.0 1.2 27.6 15.9 27.5 16.4 8.4 12.1 15.6 15.3 5.0 20.7 17.3 18.2 12.6 0.9 2.8 2.4 3.5 2.9 2.4 12.1 2.5 3.2 3.7 15.0 2.2 2.1 0.7 5.5 3.3 2.2 2.2 2.8 7.3 8.8 8.2 9.2 6.5 7.9 10.7 8.5 8.4 7.9 8.2 8.5 11.5 3.2 10.0 4.9 42.4 5.1 14.7 14.6 17.6 11.1 13.3 11.0 1.9 11.5 12.9 20.2 35.5 26.1 21.0 35.0 17.6 16.0 0.7 9.2 8.2 14.2 17.3 6.5 4.8 20.9 7.1 9.0 23.0 10.0 18.4 12.1 7.9 4.2 12.4 15.2 6.5 33.7 18.3 8.4 11.3 1.3 4.1 10.5 10.6 9.4 11.6 8.6 22.6 5.0 8.4 20.0 44.1 6.4 21.4 15.4 32.3 11.6 8.0 43.4 13.1 7.9 9.6 4.3 6.0 16.6 8.4 22.0 14.5 22.6 26.7 19.0 RALGPS2 "FLJ10244, FLJ25604, KIAA0351" ENSG00000116191 "Ral GEF with PH domain and SH3 binding motif 2" Q86X27 1 178725147-178921841 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Alzheimer disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 56.2;testis: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 263.1;Cone photoreceptor cells: 206.4;Late spermatids: 185.9;Rod photoreceptor cells: 397.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 26.7;naive B-cell: 21.0" "Lineage enriched" "Detected in many" 11 "B-cells: 26.7" "Cell line enhanced" "Detected in many" "U-266/84: 250.4;U-698: 194.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027143, HPA028328" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Cytosol" "HPA027143: AB_10602071, HPA028328: AB_10601889" "unprognostic (8.13e-2)" "unprognostic (1.46e-2)" "unprognostic (4.06e-3)" "unprognostic (2.71e-1)" "unprognostic (1.23e-1)" "unprognostic (1.50e-1)" "unprognostic (5.72e-2)" "unprognostic (6.63e-3)" "unprognostic (4.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.82e-2)" "unprognostic (7.77e-2)" "unprognostic (1.55e-1)" "unprognostic (3.45e-1)" "unprognostic (6.35e-2)" "unprognostic (4.37e-2)" "unprognostic (8.97e-2)" 5.5 8.5 3.5 24.0 5.0 13.2 8.1 4.9 4.6 6.5 3.3 13.4 11.5 9.4 5.4 16.3 8.0 8.1 4.6 7.1 5.8 6.7 32.0 2.8 52.4 3.0 2.4 18.3 5.7 7.8 2.9 9.2 2.6 7.3 12.1 52.5 5.4 5.5 1.4 19.6 16.4 11.8 3.4 28.3 13.7 77.0 5.5 15.2 6.8 4.8 56.2 12.6 7.6 2.1 39.9 12.7 38.7 0.4 42.3 61.6 15.2 34.0 74.8 27.1 24.3 15.1 38.3 83.7 11.2 100.8 13.5 32.2 17.2 8.6 35.4 0.1 10.3 0.0 8.7 14.6 7.1 11.1 0.4 27.5 7.5 35.1 24.6 18.8 23.7 15.3 20.6 3.1 17.8 6.3 17.0 3.5 26.5 15.3 13.4 23.5 39.9 0.7 9.3 24.9 6.0 17.2 22.2 24.5 48.4 26.3 29.3 5.6 17.9 12.4 11.8 45.4 16.4 91.8 250.4 194.3 7.2 5.7 14.2 0.8 0.1 2.4 0.3 0.1 0.3 26.7 0.2 0.1 0.4 21.0 0.7 0.2 1.3 0.4 0.1 0.8 0.0 1.1 3.5 5.0 4.9 4.6 7.1 5.8 3.0 2.4 2.6 3.4 5.5 2.1 5.4 12.8 6.9 29.4 263.1 14.8 16.3 5.4 14.8 97.4 27.9 15.1 17.5 15.7 8.7 14.7 206.4 7.5 11.6 39.5 21.5 15.2 123.0 23.3 25.6 4.9 35.9 22.7 84.0 12.0 10.1 18.7 48.9 33.0 8.8 60.3 2.9 55.2 6.3 13.5 92.3 22.5 0.0 8.5 4.8 185.9 50.1 7.3 8.8 41.2 5.1 27.8 10.3 107.5 4.0 31.0 52.4 46.6 105.2 26.0 22.7 9.7 23.9 397.3 19.7 41.5 18.6 146.6 34.8 29.1 34.1 3.3 10.3 20.7 15.6 72.0 RASGRP2 CALDAG-GEFI ENSG00000068831 "RAS guanyl releasing protein 2" Q7LDG7 11 64726911-64745456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 147.3;lymphoid tissue: 140.5" "Cell type enhanced" "Detected in many" "B-cells: 125.5;dendritic cells: 86.1;Kupffer cells: 77.3;Macrophages: 72.2;NK-cells: 98.9;Sertoli cells: 131.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 103.4;HL-60: 192.8;NB-4: 347.1;REH: 105.0;THP-1: 108.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015635, HPA015667" Approved Supported "Plasma membrane" NA NA 1900000 "Cluster 37: B-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA015635: , HPA015667: AB_1856090" "unprognostic (5.96e-2)" "unprognostic (3.24e-3)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (3.52e-2)" "unprognostic (4.74e-5)" "unprognostic (1.11e-2)" "unprognostic (7.36e-3)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.91e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" 23.8 10.1 16.1 52.9 35.5 147.3 16.8 9.6 22.4 20.1 7.1 37.5 6.6 28.3 4.6 9.1 29.2 8.7 51.7 13.4 13.4 15.8 10.1 29.5 106.0 12.4 16.3 9.1 4.1 1.0 5.5 10.9 11.9 23.2 5.3 1.3 4.6 18.6 12.2 6.1 86.4 15.0 9.5 140.5 17.5 11.9 20.7 34.6 10.6 10.2 62.0 26.7 15.5 9.8 0.1 0.1 3.0 0.1 0.0 0.3 8.7 1.3 0.2 1.2 0.8 1.5 0.2 62.8 2.7 0.2 0.8 0.7 5.4 0.9 0.3 0.3 1.7 103.4 0.0 0.4 0.3 192.8 35.9 0.0 0.0 0.5 0.0 0.0 0.1 25.9 4.1 1.1 0.0 1.4 45.4 347.1 2.5 0.4 0.0 105.0 0.2 4.4 0.0 0.0 0.5 2.3 0.1 0.1 0.0 2.2 0.6 108.5 0.6 0.0 2.0 1.5 0.1 0.5 0.1 58.9 0.0 58.2 0.0 64.4 34.1 59.9 70.4 88.0 37.3 170.7 72.9 57.2 34.5 100.2 92.7 83.1 70.9 55.3 105.8 85.9 93.8 67.5 16.1 35.5 9.6 22.4 13.4 13.4 12.4 16.3 11.9 9.5 20.7 9.8 27.4 3.2 1.8 2.6 125.5 2.3 0.1 0.0 0.0 2.6 1.6 3.7 53.1 2.8 0.0 0.0 0.0 1.7 86.1 0.1 0.0 0.0 6.6 1.9 27.1 13.5 0.0 24.2 6.0 0.0 1.3 6.6 2.6 1.2 3.8 5.7 31.4 1.7 6.1 0.0 12.2 0.1 0.0 77.3 19.7 19.5 18.0 72.2 0.0 6.5 55.8 0.7 98.9 2.5 0.9 0.0 0.0 47.8 28.6 0.1 0.4 0.9 0.7 2.5 131.5 5.4 56.8 18.0 43.9 0.9 1.3 11.8 61.0 0.8 0.3 0.2 RBBP5 "RBQ3, SWD1" ENSG00000117222 "RB binding protein 5, histone lysine methyltransferase complex subunit" Q15291 1 205086142-205122015 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049042, HPA058085" Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" "HPA049042: AB_2680610, HPA058085: AB_2683600" "unprognostic (8.72e-2)" "unprognostic (6.35e-2)" "unprognostic (2.14e-2)" "unprognostic (1.36e-2)" "unprognostic (1.60e-1)" "unprognostic (1.17e-1)" "unprognostic (4.61e-3)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.88e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-2)" "unprognostic (6.90e-2)" "unprognostic (3.78e-3)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "unprognostic (4.88e-2)" 6.3 8.2 4.7 7.2 5.3 9.5 7.9 6.4 6.4 7.8 2.7 7.0 7.1 8.1 7.5 7.0 7.5 6.1 6.4 5.7 5.3 12.4 11.0 6.6 11.3 3.4 3.8 9.5 8.2 9.4 6.1 6.5 3.8 6.9 8.0 9.8 7.6 6.9 8.7 8.5 6.7 7.1 4.3 9.3 6.7 6.1 4.5 13.2 9.8 9.9 12.8 7.5 5.2 6.4 16.3 16.9 16.0 19.0 21.8 12.5 17.3 15.2 12.9 19.0 18.8 17.9 19.1 25.3 11.3 11.1 15.5 18.2 26.9 10.1 22.4 21.6 14.5 21.2 16.4 14.6 14.1 26.9 16.6 10.1 12.9 17.6 15.0 12.7 15.4 17.9 41.6 25.2 16.0 15.0 26.1 11.3 26.1 14.2 27.9 22.9 33.9 31.6 13.2 11.7 25.0 20.1 21.3 22.3 19.2 19.0 24.2 14.9 11.8 15.6 16.6 23.1 20.2 12.2 18.3 30.6 13.9 16.5 24.5 22.0 4.9 7.9 8.0 6.4 8.5 7.8 7.4 8.1 5.4 6.2 7.1 8.7 11.6 8.2 8.3 6.0 8.1 3.5 4.7 5.3 6.4 6.4 5.7 5.3 3.4 3.8 3.8 4.3 4.5 6.4 14.7 19.2 12.2 11.4 31.0 26.9 9.7 5.9 15.9 14.5 18.9 14.6 7.1 8.6 13.4 22.0 29.2 9.1 25.2 15.8 9.8 12.1 7.3 13.1 14.0 13.2 12.1 23.1 19.9 11.6 10.7 13.5 9.7 21.0 13.9 25.6 17.2 21.8 10.9 16.8 15.7 14.0 10.2 15.6 25.9 3.2 12.8 17.9 19.6 8.4 15.6 12.6 15.5 14.6 21.2 13.6 9.8 16.1 25.9 13.5 14.7 28.8 13.2 18.3 19.7 21.9 14.1 10.2 20.4 14.6 33.8 10.8 27.9 12.6 15.8 13.4 RCSD1 "CapZIP, MGC21854, MK2S4" ENSG00000198771 "RCSD domain containing 1" Q6JBY9 1 167630093-167708696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 115.5;skeletal muscle: 147.9" "Cell type enhanced" "Detected in many" "B-cells: 258.0;Kupffer cells: 137.5;Macrophages: 80.7;Microglial cells: 78.7;monocytes: 121.6;NK-cells: 142.2;Sertoli cells: 78.9;T-cells: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 195.2;HDLM-2: 91.0;REH: 224.0;RPMI-8226: 139.7;THP-1: 103.4;U-266/70: 132.0;U-698: 132.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016597, HPA073490" Enhanced Approved "Plasma membrane" NA NA 200000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA016597: AB_2669397, HPA073490: " "unprognostic (2.13e-2)" "unprognostic (7.38e-3)" "unprognostic (6.50e-3)" "unprognostic (1.37e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.97e-4)" "unprognostic (5.51e-2)" "unprognostic (8.90e-3)" "unprognostic (3.65e-1)" "unprognostic (8.48e-2)" "unprognostic (1.01e-1)" "unprognostic (6.33e-2)" "unprognostic (2.53e-3)" "unprognostic (3.19e-1)" "unprognostic (3.58e-2)" "unprognostic (6.94e-2)" "unprognostic (3.97e-2)" 14.2 5.8 5.5 42.9 6.1 55.7 11.6 5.8 6.3 5.6 5.9 12.0 8.8 4.6 2.5 8.6 4.0 11.7 25.6 5.2 6.3 5.2 8.0 16.8 88.7 9.9 7.3 2.8 1.5 2.4 2.0 17.5 8.4 3.7 11.9 0.6 4.7 3.9 147.9 2.8 29.3 8.6 6.8 52.4 12.4 3.7 7.7 115.5 6.1 50.6 73.7 14.0 3.4 10.0 0.3 0.0 0.2 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 195.2 0.6 0.2 0.0 0.2 0.0 0.0 0.0 91.0 0.3 1.6 0.1 0.1 0.2 34.4 3.7 0.5 0.3 0.4 0.0 0.0 0.0 76.0 67.8 56.7 25.4 0.0 69.3 49.8 1.7 0.0 0.0 224.0 0.8 139.7 0.0 0.1 0.1 0.1 0.2 0.6 0.1 2.7 0.1 103.4 0.5 0.2 0.6 0.2 0.4 132.0 42.5 132.0 0.1 64.6 0.0 249.3 170.3 271.3 63.5 119.8 76.9 216.4 81.7 80.0 103.4 201.7 68.1 64.7 165.7 130.0 122.7 54.3 129.4 148.9 5.5 6.1 5.8 6.3 5.2 6.3 9.9 7.3 8.4 6.8 7.7 10.0 18.7 3.2 6.7 0.3 258.0 1.1 1.2 0.0 3.4 0.7 6.2 10.7 46.8 0.0 3.1 1.8 0.0 0.5 73.9 0.1 0.0 0.2 0.8 0.4 2.1 18.8 0.0 30.1 4.2 0.0 0.5 12.4 4.1 0.3 13.9 0.2 19.2 1.5 44.2 0.0 0.7 0.0 0.0 137.5 26.9 1.7 0.9 80.7 5.4 78.7 121.6 0.2 142.2 2.0 0.6 0.1 0.0 0.4 55.1 0.8 0.0 0.5 0.0 0.8 78.9 5.8 39.7 0.0 0.3 1.0 1.7 1.2 97.2 0.6 0.1 0.3 RFX5 ENSG00000143390 "Regulatory factor X5" P48382 1 151340640-151347326 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018519, HPA079241" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Vesicles "HPA018519: AB_1856209, HPA079241: " "unprognostic (1.17e-3)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" "unprognostic (3.21e-2)" "unprognostic (2.68e-2)" "unprognostic (2.49e-2)" "unprognostic (3.73e-2)" "unprognostic (2.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.96e-1)" "unprognostic (8.29e-2)" "unprognostic (4.42e-2)" "unprognostic (5.66e-3)" "unprognostic (2.00e-3)" "unprognostic (3.43e-2)" "unprognostic (4.03e-2)" "unprognostic (3.05e-2)" 18.4 25.6 13.3 43.3 13.7 24.0 14.9 17.8 13.2 18.2 11.7 22.7 31.6 22.0 13.1 18.3 18.4 23.4 18.3 12.3 16.8 18.3 13.1 27.9 67.7 17.1 17.6 10.1 9.6 22.1 18.1 12.4 18.5 20.4 28.1 14.6 16.0 25.1 17.0 13.1 26.1 31.8 15.4 50.7 19.6 15.5 15.7 50.5 23.7 23.8 71.8 26.5 11.4 13.3 37.7 41.8 57.6 32.8 27.6 24.0 12.6 17.8 30.0 43.6 57.7 13.7 50.9 145.2 63.9 21.5 42.6 59.5 24.9 34.4 31.9 177.4 39.7 54.8 89.4 23.0 17.7 48.9 59.4 25.2 18.8 28.8 13.2 35.7 39.9 92.0 26.8 88.3 33.8 34.2 78.7 36.2 41.9 30.5 21.2 97.1 32.3 80.1 42.0 49.1 20.4 60.0 35.7 55.0 52.8 69.2 51.6 114.3 39.9 23.8 25.1 11.8 33.7 110.9 118.2 168.6 37.8 26.4 31.3 5.6 22.6 11.5 17.4 28.2 15.3 47.9 13.9 17.4 47.4 53.3 10.9 12.2 3.1 31.4 30.8 25.1 28.5 21.5 13.3 13.7 17.8 13.2 12.3 16.8 17.1 17.6 18.5 15.4 15.7 13.3 8.4 9.6 7.5 4.9 32.0 6.6 12.5 11.4 14.2 7.6 9.4 6.5 5.1 8.6 12.1 7.3 0.0 8.8 16.9 3.8 9.8 15.7 8.4 7.5 6.3 9.9 4.2 16.6 3.2 9.2 3.4 6.1 5.6 12.8 24.1 9.4 10.8 7.3 12.4 1.7 7.0 5.1 10.2 18.5 15.7 17.9 5.0 13.3 5.4 8.4 40.8 7.2 21.6 3.0 2.4 8.6 2.7 9.8 9.5 14.1 11.2 10.7 7.4 2.7 6.6 5.3 5.7 15.5 7.5 14.2 6.1 3.4 13.7 15.7 7.3 14.6 RGS19 "GAIP, RGSGAIP" ENSG00000171700 "Regulator of G protein signaling 19" P49795 20 64073181-64079988 "Predicted intracellular proteins" Autophagy "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.2;lymphoid tissue: 77.5" "Cell type enhanced" "Detected in many" "B-cells: 97.8;dendritic cells: 82.0;Hofbauer cells: 135.0;Kupffer cells: 104.6;Macrophages: 101.6;monocytes: 86.3;NK-cells: 140.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 154.2;NB-4: 128.1;THP-1: 107.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056384, HPA069984" Enhanced Supported "Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Cell Junctions" "Nucleoli fibrillar center" "HPA056384: AB_2732602, HPA069984: AB_2732145" "unprognostic (3.98e-2)" "unprognostic (2.32e-1)" "unprognostic (4.26e-3)" "unprognostic (8.42e-2)" "unprognostic (2.03e-1)" "unprognostic (9.94e-2)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.25e-2)" "unprognostic (2.41e-2)" "unprognostic (3.91e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "prognostic unfavorable (2.06e-9)" "unprognostic (1.35e-1)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (4.66e-3)" 12.5 8.8 7.1 28.5 6.8 57.2 9.0 7.3 7.8 5.9 6.3 6.7 7.5 5.1 2.0 8.1 6.9 6.0 6.4 6.7 7.3 7.6 5.9 19.6 35.2 12.3 8.8 2.3 7.0 2.7 4.3 7.2 10.0 7.3 2.2 0.3 8.5 2.5 2.5 8.4 21.1 4.3 11.4 77.5 8.2 1.8 11.8 13.9 6.8 2.2 17.3 8.3 6.9 12.2 16.1 24.1 6.8 12.2 3.0 4.9 11.5 10.0 6.9 20.2 8.4 36.0 21.8 28.1 27.0 6.2 21.6 15.4 7.0 12.8 4.8 14.0 13.2 40.3 12.3 14.8 4.0 83.0 154.2 3.3 7.7 8.6 3.0 4.0 13.3 18.4 15.5 14.5 6.2 28.6 61.6 128.1 7.0 13.8 30.3 51.1 4.0 20.4 5.7 7.8 12.9 12.1 10.3 6.3 13.6 3.4 8.3 107.3 14.0 18.9 9.5 3.3 9.8 9.1 7.6 34.7 10.5 62.6 12.8 289.5 273.2 760.9 96.6 396.0 99.2 125.7 91.1 92.6 228.8 125.7 62.4 64.9 606.5 75.1 458.3 130.8 107.1 204.7 7.1 6.8 7.3 7.8 6.7 7.3 12.3 8.8 10.0 11.4 11.8 12.2 19.0 3.2 4.1 2.0 97.8 9.7 6.4 8.0 4.0 0.1 10.4 13.3 3.9 2.8 5.7 1.8 0.0 3.0 82.0 0.5 0.0 12.0 0.5 2.8 8.3 17.2 0.0 14.7 1.4 14.3 8.1 6.5 4.6 2.2 48.8 4.5 15.0 0.8 135.0 0.0 1.0 0.5 4.1 104.6 50.0 1.1 4.4 101.6 5.4 17.8 86.3 0.3 140.1 2.5 0.2 16.9 3.8 1.2 25.0 14.5 0.1 2.4 3.3 0.2 13.1 2.4 8.8 0.3 7.0 5.2 8.9 1.8 57.1 3.7 0.9 8.8 RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Microglial cells: 57.1;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 73.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: AB_2683343" "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" 10.3 8.9 11.2 13.6 20.9 11.9 11.5 12.2 13.6 11.6 1.8 11.5 10.3 13.6 12.5 11.5 12.9 10.9 10.3 8.8 15.2 12.0 15.1 9.9 16.1 15.6 15.0 13.6 13.9 16.5 4.4 9.9 17.1 13.1 11.2 7.4 9.6 13.3 8.9 8.8 11.8 14.3 15.7 14.2 11.4 17.4 16.8 37.5 15.6 8.6 16.9 11.5 7.0 22.8 10.7 9.3 9.9 15.1 28.6 28.8 0.0 24.1 20.9 12.6 14.6 8.3 18.7 10.1 19.8 25.2 18.0 11.9 0.1 26.8 23.9 25.1 9.9 15.3 5.9 6.7 31.5 15.2 8.0 25.6 38.2 23.8 51.4 14.3 9.8 26.7 41.7 25.6 13.4 18.9 27.8 8.5 0.0 12.2 10.3 12.0 0.1 14.9 10.3 13.3 9.7 7.3 13.6 5.1 18.8 17.6 14.1 18.9 13.1 5.6 12.2 22.0 7.5 28.8 14.9 73.9 17.8 19.6 16.2 10.4 13.7 12.8 7.3 20.0 11.8 22.1 11.0 8.9 17.2 24.5 12.6 10.6 3.3 11.8 13.8 21.1 16.2 10.8 11.2 20.9 12.2 13.6 8.8 15.2 15.6 15.0 17.1 15.7 16.8 22.8 6.6 12.8 6.4 66.9 28.4 5.2 8.5 7.2 8.0 8.0 7.6 4.2 16.6 4.3 8.1 11.0 16.7 7.6 9.3 6.6 3.9 7.0 16.7 8.3 8.6 6.8 1.8 15.2 28.4 9.3 4.1 9.3 8.2 7.8 8.2 22.7 3.3 14.0 5.2 11.8 41.5 6.1 6.1 8.2 4.4 24.4 5.6 7.6 12.4 57.1 6.2 6.3 9.2 55.8 109.0 8.3 1.9 6.8 48.8 13.2 6.8 3.4 7.1 6.3 0.0 5.6 6.6 15.2 9.5 7.3 5.5 5.6 8.6 25.7 5.7 8.9 RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 58.4;Kupffer cells: 57.3;NK-cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 75.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "HPA018080: AB_2178634" "unprognostic (1.19e-1)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (5.11e-3)" "unprognostic (4.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (9.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.96e-11)" "unprognostic (5.24e-2)" "unprognostic (2.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" 18.3 10.1 9.4 31.2 8.6 29.7 13.6 11.7 11.0 8.8 11.6 9.0 6.5 7.4 1.6 23.9 10.1 10.3 10.3 9.7 12.1 10.9 6.3 24.8 27.6 26.6 17.2 8.0 19.5 3.1 5.3 9.7 22.4 9.1 4.4 2.9 11.6 2.6 13.5 29.1 26.6 6.4 20.9 42.2 10.5 3.0 30.0 6.5 12.3 3.1 21.3 11.0 15.7 28.8 38.3 43.3 1.3 10.7 0.4 1.1 30.1 8.6 26.9 6.7 9.1 13.3 45.0 41.5 28.6 10.9 39.0 29.9 7.3 40.8 6.2 7.1 13.6 2.8 3.5 21.8 25.6 1.8 5.9 4.5 20.2 18.1 20.7 15.4 20.3 5.9 4.3 18.3 4.6 30.7 4.3 4.7 6.7 25.7 26.1 10.3 0.4 75.3 17.8 14.0 9.2 12.6 9.9 28.7 38.7 8.5 24.7 11.4 32.4 0.6 14.4 0.7 11.0 44.3 22.6 33.7 24.3 11.2 27.1 6.3 13.4 4.3 8.0 13.1 5.5 12.7 2.1 5.8 6.5 7.4 1.5 3.6 10.2 4.9 12.2 10.0 1.1 8.8 9.4 8.6 11.7 11.0 9.7 12.1 26.6 17.2 22.4 20.9 30.0 28.8 22.3 6.4 6.9 2.3 58.4 17.6 15.3 35.0 8.0 4.2 4.7 5.5 3.3 18.6 19.2 3.7 2.1 1.0 47.1 2.0 0.0 21.3 0.5 4.2 0.8 15.3 1.8 1.3 0.6 9.8 2.2 4.7 7.7 6.6 0.0 15.4 7.9 3.4 37.6 0.0 0.5 4.1 6.1 57.3 42.7 0.7 0.9 48.8 10.6 38.4 40.1 1.1 64.9 1.0 0.1 14.2 4.8 0.4 36.5 20.4 1.9 1.8 16.2 1.4 6.6 3.6 3.2 0.7 7.1 9.9 29.3 1.6 22.3 2.8 7.8 20.4 RIC1 "bA207C16.1, KIAA1432" ENSG00000107036 "RIC1 homolog, RAB6A GEF complex partner 1" Q4ADV7 9 5629025-5776557 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 62.3;Excitatory neurons: 84.5;Inhibitory neurons: 79.6;Microglial cells: 98.4;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 70.6;Plasma cells: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 73.3;HEL: 91.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051578 Supported NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "HPA051578: AB_2681541" "unprognostic (1.78e-1)" "unprognostic (4.08e-2)" "unprognostic (3.13e-2)" "unprognostic (2.47e-2)" "unprognostic (4.51e-2)" "unprognostic (8.87e-2)" "unprognostic (8.59e-2)" "unprognostic (1.90e-1)" "unprognostic (3.87e-2)" "unprognostic (7.16e-2)" "unprognostic (8.96e-2)" "unprognostic (3.92e-2)" "unprognostic (3.74e-1)" "unprognostic (3.50e-2)" "unprognostic (4.67e-2)" "unprognostic (1.28e-1)" "unprognostic (5.77e-2)" 11.8 7.2 3.2 12.7 7.3 13.2 9.8 10.2 5.2 11.6 11.1 8.4 10.0 11.6 8.7 11.4 8.8 11.4 6.9 4.2 5.6 7.5 9.9 10.1 17.3 7.3 5.5 10.3 10.5 8.9 4.9 14.3 7.4 8.2 9.4 7.4 11.3 10.5 17.6 13.5 9.3 13.3 4.3 11.8 7.9 11.6 6.3 14.8 11.3 15.7 16.5 11.0 10.0 10.1 18.5 10.7 18.3 12.6 20.8 24.1 15.3 26.1 24.0 17.6 22.8 9.8 3.9 41.8 3.1 27.1 7.0 8.8 13.9 14.4 24.4 73.3 9.2 91.5 23.3 10.6 17.2 14.4 15.7 22.7 9.7 12.1 18.7 20.1 21.2 13.0 5.5 48.5 14.7 4.6 11.9 26.0 9.2 7.0 5.3 22.8 12.0 16.9 9.2 7.1 5.0 12.4 14.2 8.8 7.3 29.1 7.9 24.1 20.5 14.2 17.7 8.0 12.4 13.4 18.0 51.8 5.8 5.5 4.9 0.3 0.6 0.5 0.3 1.0 0.4 0.7 0.4 0.5 0.5 0.2 0.2 0.3 0.3 1.0 0.5 0.7 0.5 0.5 3.2 7.3 10.2 5.2 4.2 5.6 7.3 5.5 7.4 4.3 6.3 10.1 11.7 9.6 4.8 62.3 45.9 0.0 5.8 0.0 42.1 7.1 6.9 5.5 4.4 10.0 0.0 0.0 4.2 7.4 12.1 5.6 1.9 3.9 9.6 8.1 12.8 8.7 3.6 17.9 84.5 5.4 4.6 13.5 25.0 10.1 5.1 7.6 9.7 10.7 7.8 21.9 79.6 2.7 0.0 25.7 0.0 9.5 8.7 19.8 0.0 98.4 20.8 2.5 7.2 69.9 70.6 5.6 2.7 6.4 80.1 6.1 7.0 3.3 0.7 5.9 13.1 10.1 11.1 8.0 4.1 32.0 0.0 7.3 15.3 6.4 2.8 8.1 RNASEH2B "AGS2, DLEU8, FLJ11712" ENSG00000136104 "Ribonuclease H2 subunit B" Q5TBB1 13 50909747-51024120 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 132.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 351.0;NB-4: 259.8;REH: 286.0;THP-1: 258.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040084, HPA041469" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA040084: AB_10697714, HPA041469: AB_2677496" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (2.80e-2)" "unprognostic (3.20e-1)" "unprognostic (2.59e-1)" "unprognostic (1.16e-1)" "unprognostic (8.33e-2)" "unprognostic (2.79e-2)" "unprognostic (2.50e-2)" "unprognostic (9.63e-3)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (2.54e-8)" "unprognostic (1.05e-1)" "unprognostic (3.13e-1)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" 17.7 14.8 13.2 28.6 13.5 58.4 19.5 14.5 15.2 16.0 8.7 22.3 16.7 18.8 14.1 17.6 24.9 17.1 25.2 11.9 11.5 14.8 15.0 20.5 45.7 12.2 12.1 21.2 25.7 17.1 8.3 19.6 12.0 19.2 22.0 4.7 20.2 21.6 23.8 13.5 19.8 26.8 12.4 26.3 19.2 17.3 13.7 132.6 27.4 6.0 38.4 22.9 9.4 15.4 41.1 33.1 17.6 37.5 22.9 45.9 41.7 28.6 32.4 40.6 34.0 43.1 61.2 114.4 17.8 29.4 38.4 38.2 55.8 26.1 48.4 42.2 47.1 102.7 22.4 25.4 31.2 191.2 66.0 17.9 33.4 35.9 31.8 36.8 36.3 238.0 58.7 52.7 55.4 19.2 351.0 259.8 57.9 87.2 25.7 286.0 51.4 77.7 30.6 23.6 38.8 56.8 34.4 12.6 38.0 22.8 19.7 258.7 25.6 36.0 30.1 42.7 64.3 69.8 50.3 135.6 9.5 140.6 43.1 3.5 37.5 17.8 31.6 43.3 35.7 104.2 61.9 51.4 55.1 86.4 54.4 51.9 6.1 38.0 38.3 94.0 107.5 54.1 13.2 13.5 14.5 15.2 11.9 11.5 12.2 12.1 12.0 12.4 13.7 15.4 21.2 38.5 23.8 17.6 85.8 18.7 30.5 43.7 22.2 14.1 31.1 35.8 47.4 18.6 27.4 16.5 6.2 40.7 92.3 9.7 29.4 41.7 74.0 30.1 33.2 14.9 12.1 107.7 31.1 50.5 55.7 26.7 13.7 18.2 52.6 62.0 16.4 15.1 97.3 1.7 35.4 21.8 24.4 59.0 22.0 38.2 27.7 50.4 16.0 45.0 86.4 11.7 45.3 44.2 59.5 24.7 9.9 29.7 75.6 34.5 12.1 28.4 37.3 6.2 13.1 21.8 28.9 91.4 44.3 26.9 21.0 17.9 56.5 36.9 35.4 29.3 RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202179-56221933 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: AB_1856370" "unprognostic (1.14e-2)" "unprognostic (6.30e-2)" "unprognostic (4.04e-2)" "unprognostic (6.86e-2)" "unprognostic (9.59e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (6.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" 32.2 24.6 22.5 18.0 23.3 19.6 21.4 15.7 23.8 21.2 13.0 23.8 12.4 22.3 13.2 23.1 24.3 25.5 32.7 24.6 24.8 19.7 15.1 23.8 23.4 16.8 19.1 22.9 23.0 27.4 22.8 21.3 21.2 33.9 19.0 23.8 15.0 20.7 34.0 15.0 16.1 28.5 15.3 20.6 17.0 15.9 23.5 26.5 28.6 40.8 25.1 28.2 17.0 19.2 21.6 32.6 34.7 55.2 71.0 51.3 25.8 70.8 69.5 62.2 50.2 40.0 27.6 41.6 36.7 60.2 20.6 24.3 47.4 34.1 44.9 43.8 25.7 55.8 22.3 23.2 148.3 61.6 58.3 66.0 78.6 52.0 91.0 81.7 61.3 34.5 40.4 41.3 35.1 34.9 35.6 27.6 41.9 21.6 37.8 38.2 24.9 25.3 33.3 31.3 62.9 38.1 61.9 35.0 55.4 34.3 49.2 71.3 37.3 31.3 32.9 40.6 27.8 29.6 36.6 37.5 37.2 36.4 38.0 59.1 27.2 99.9 27.6 26.7 24.9 50.3 23.0 24.3 30.6 55.1 23.4 24.0 36.2 33.1 28.3 23.7 29.4 31.0 22.5 23.3 15.7 23.8 24.6 24.8 16.8 19.1 21.2 15.3 23.5 19.2 18.9 44.8 22.6 11.1 42.2 12.0 19.9 8.6 19.9 30.7 22.2 21.1 24.6 24.3 18.8 16.5 22.9 15.2 17.0 10.2 17.6 15.3 92.8 13.9 14.2 20.7 20.4 11.1 15.0 21.3 18.5 22.7 9.7 14.2 25.9 16.8 30.0 16.7 19.3 28.6 15.7 13.9 8.2 34.9 22.7 58.0 23.0 25.0 7.2 9.4 33.5 26.2 15.5 14.6 12.3 20.8 20.3 25.9 14.6 33.5 12.3 19.6 18.0 18.3 26.3 23.2 27.4 10.4 14.2 14.4 16.6 16.8 16.6 17.1 14.3 23.1 RNGTT "hCAP, HCE, HCE1" ENSG00000111880 "RNA guanylyltransferase and 5'-phosphatase" O60942 6 88609897-88963618 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA capping, mRNA processing" "Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Protein phosphatase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 108.6;Inhibitory neurons: 110.2;Oligodendrocyte precursor cells: 96.5;Oligodendrocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003750 Approved Approved Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA003750: AB_1856383" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (2.82e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.48e-3)" "unprognostic (1.28e-1)" "unprognostic (4.05e-3)" "unprognostic (3.76e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-3)" "unprognostic (9.83e-2)" "unprognostic (6.55e-2)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" 5.3 6.7 4.9 8.2 4.9 9.5 5.6 9.1 5.7 5.2 2.6 4.6 4.2 5.2 3.6 7.2 4.1 3.7 5.3 5.1 7.0 5.3 6.9 4.4 17.2 4.6 5.2 4.8 2.9 6.4 4.9 5.0 5.1 5.3 5.4 10.6 3.5 4.9 5.2 4.4 5.2 6.1 4.6 7.6 4.2 9.3 7.3 14.7 5.6 6.4 17.3 6.2 4.8 5.3 9.2 14.0 21.1 26.2 12.0 12.6 12.4 20.2 13.4 16.4 20.4 15.9 6.8 23.1 16.2 14.9 21.5 11.1 24.7 16.5 29.7 31.8 19.0 30.5 11.4 12.2 9.5 33.2 16.6 7.7 13.8 16.8 15.9 13.6 14.7 12.7 30.9 18.1 23.8 12.0 14.6 22.8 12.5 15.0 11.7 28.6 32.0 13.3 14.0 14.2 12.3 17.3 16.8 9.8 11.1 19.7 10.8 31.8 11.5 13.0 12.0 14.7 27.9 16.1 31.6 13.2 18.9 23.8 24.1 5.2 4.1 7.6 7.8 5.9 7.8 22.9 8.6 9.7 5.8 22.8 9.7 10.1 3.4 10.9 5.5 4.0 9.0 5.4 4.9 4.9 9.1 5.7 5.1 7.0 4.6 5.2 5.1 4.6 7.3 5.3 8.9 0.0 16.2 54.5 60.4 8.3 10.7 6.0 10.8 22.4 6.5 6.1 10.7 7.2 12.9 12.9 39.6 10.4 19.7 8.0 0.0 6.3 17.9 7.9 12.1 7.0 9.1 7.6 108.6 4.9 9.9 9.7 15.8 12.4 8.8 11.0 7.5 10.3 7.8 15.2 110.2 7.0 4.1 9.1 7.3 5.2 5.9 13.6 3.6 69.3 9.8 7.2 18.6 96.5 94.3 7.2 5.1 7.9 42.3 8.6 4.6 6.3 10.1 43.4 6.6 15.8 9.5 23.3 20.1 10.7 8.7 11.8 24.6 8.0 6.7 7.4 RP9 PAP-1 ENSG00000164610 "RP9 pre-mRNA splicing factor" Q8TA86 7 33094797-33109404 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031523, HPA050778" Uncertain Enhanced Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Vesicles, Cytosol" "HPA031523: AB_10603235, HPA050778: AB_2681233" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (1.07e-2)" "unprognostic (1.82e-1)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.58e-4)" "unprognostic (6.71e-2)" "unprognostic (6.22e-2)" "unprognostic (7.53e-2)" "unprognostic (7.03e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.65e-5)" "unprognostic (4.19e-2)" "unprognostic (2.63e-2)" "unprognostic (2.70e-1)" "unprognostic (1.61e-1)" 12.6 15.0 26.3 8.7 26.1 21.6 12.6 28.0 51.2 17.0 26.7 16.7 9.0 14.4 15.5 10.1 14.0 6.2 29.2 25.8 26.3 17.2 13.8 12.0 15.6 26.6 26.3 16.2 20.2 10.5 10.3 10.2 26.7 14.4 9.8 16.7 11.5 11.7 36.3 13.8 15.9 8.4 25.8 20.8 13.5 18.1 26.9 13.8 16.0 34.3 16.7 14.3 13.1 27.4 20.9 28.8 29.7 34.1 18.5 17.2 14.3 26.4 21.6 28.9 23.0 25.6 14.6 26.2 17.0 21.1 35.4 20.4 36.4 22.0 36.8 11.9 25.1 19.2 22.8 24.4 32.4 26.0 13.0 17.5 20.2 32.8 64.5 23.3 24.0 27.1 35.2 23.0 29.1 42.6 27.7 69.6 25.4 27.2 21.9 28.2 26.4 17.1 21.1 19.3 28.7 39.5 18.7 39.6 46.2 35.1 20.8 35.0 19.4 28.4 40.9 25.6 42.8 38.1 37.2 51.7 20.0 36.3 56.1 21.9 12.0 21.6 15.2 9.8 14.1 57.8 16.3 17.4 13.2 77.3 19.1 18.0 2.0 15.7 12.5 28.4 15.8 8.8 26.3 26.1 28.0 51.2 25.8 26.3 26.6 26.3 26.7 25.8 26.9 27.4 21.3 12.8 10.1 4.9 35.6 21.0 15.1 11.3 29.0 15.8 17.7 27.9 41.7 17.2 10.9 14.7 14.6 20.2 16.8 12.6 21.5 16.0 5.6 14.6 28.2 24.1 10.2 19.4 6.5 15.8 20.0 20.4 20.4 16.6 3.8 26.8 15.4 16.4 18.4 8.4 7.5 19.3 24.4 10.1 14.9 3.2 18.0 12.0 23.2 5.6 10.1 21.9 21.6 3.0 8.7 14.6 8.0 16.1 24.4 22.9 16.1 18.6 8.5 16.4 26.3 19.4 30.3 31.6 54.3 24.4 18.0 10.4 19.9 22.9 18.4 12.0 RPS4Y2 RPS4Y2P ENSG00000280969 "Ribosomal protein S4 Y-linked 2" Q8TD47 Y 20756108-20781032 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "prostate: 1.9;testis: 1.1" "Cell type enhanced" "Detected in some" "B-cells: 3.5;Basal keratinocytes: 3.2;Basal prostatic cells: 3.5;Langerhans cells: 3.4;Prostatic glandular cells: 2.1;Spermatogonia: 2.6;Suprabasal keratinocytes: 5.8" "Cancer enriched" "Detected in single" 9 "prostate cancer: 1.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.4" "Cell line enriched" "Detected in single" 5 "U-266/84: 2.0" HPA000857 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "HPA000857: AB_1079849" "unprognostic (1.50e-2)" "unprognostic (3.63e-1)" "unprognostic (6.39e-6)" "unprognostic (5.92e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.2 0.1 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.2 3.5 0.6 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 3.4 0.0 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.7 0.6 1.1 2.6 0.0 5.8 0.3 0.4 0.0 0.0 1.3 SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "B-cells: 66.4;Hofbauer cells: 26.2;Kupffer cells: 120.3;Macrophages: 66.3;monocytes: 60.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cell line enhanced" "Detected in many" "HeLa: 6.8;U-698: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" 5.9 4.1 0.0 30.4 0.1 5.1 1.4 2.7 1.3 1.5 3.6 4.5 5.4 2.9 1.1 1.9 3.1 7.3 1.7 0.3 0.0 2.3 10.6 16.2 39.4 0.6 0.1 3.6 3.9 0.8 0.7 3.9 0.1 3.1 4.6 7.5 4.0 1.4 4.3 3.2 10.2 6.1 0.0 49.2 5.0 2.8 0.0 5.1 3.4 0.8 44.9 6.0 0.6 0.4 1.0 1.5 2.5 3.3 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.7 2.1 4.8 0.9 0.0 1.8 1.0 0.0 0.0 0.0 0.8 2.1 2.0 6.8 0.7 0.0 0.2 0.7 0.0 0.1 0.0 0.2 1.2 0.0 4.2 0.1 1.2 0.0 1.6 2.4 0.7 1.1 0.3 1.4 2.2 0.5 0.5 0.0 0.6 1.8 0.8 1.8 0.6 1.3 0.7 2.6 2.4 0.3 0.3 1.1 1.4 0.6 0.7 0.3 10.8 1.2 0.3 0.7 16.8 110.6 3.0 1.3 239.0 1.5 145.8 0.8 1.2 84.2 124.5 1.7 1.2 19.0 5.3 265.5 3.2 1.4 68.0 0.0 0.1 2.7 1.3 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.4 0.5 0.0 4.4 2.6 66.4 0.4 0.4 0.0 0.0 2.5 0.4 0.5 0.4 1.5 0.6 0.0 12.5 0.3 1.5 0.0 0.0 0.7 1.4 0.4 0.3 2.0 0.0 0.4 6.5 0.9 0.3 0.6 0.0 0.1 1.3 0.4 3.3 1.9 26.2 1.7 4.9 0.0 0.0 120.3 4.2 0.7 0.3 66.3 0.0 8.4 60.3 0.4 10.3 4.0 2.3 0.4 0.0 0.4 1.7 0.3 0.0 1.0 1.6 4.1 0.0 0.7 0.3 0.5 0.8 0.0 0.4 0.1 3.2 0.2 0.0 0.4 SF1 "ZCCHC25, ZFM1, ZNF162" ENSG00000168066 "Splicing factor 1" Q15637 11 64764606-64778786 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018883 Supported Supported Nucleoplasm NA NA 130000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA018883: AB_1856763" "unprognostic (1.24e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.01e-2)" "unprognostic (1.50e-1)" "unprognostic (4.35e-1)" "prognostic unfavorable (4.85e-5)" "unprognostic (3.72e-1)" "unprognostic (4.51e-3)" "unprognostic (1.39e-1)" "unprognostic (4.62e-3)" "unprognostic (6.20e-2)" "unprognostic (8.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.78e-1)" 111.7 89.1 47.2 73.1 47.9 230.4 100.8 70.8 73.7 106.8 39.7 112.6 62.3 110.5 46.3 98.2 118.7 53.8 93.0 44.2 64.4 97.9 100.4 85.0 95.8 51.5 40.2 142.4 103.3 52.0 97.7 53.4 42.2 105.7 42.5 46.3 87.4 58.4 149.2 96.3 110.5 63.4 27.7 133.6 104.5 110.2 53.3 91.2 99.6 73.3 80.4 98.4 92.3 57.9 141.2 165.4 151.1 131.0 82.4 65.5 178.8 98.9 83.6 130.3 100.3 142.0 154.8 223.6 120.2 111.4 119.4 163.8 172.2 171.0 110.3 167.1 115.0 144.6 107.6 107.0 130.7 155.0 143.7 86.0 87.1 165.2 172.3 77.0 118.9 145.0 216.4 141.5 100.8 145.1 294.2 217.9 206.5 126.2 117.5 253.2 104.7 177.7 87.5 151.8 119.6 157.4 138.1 118.8 138.3 95.6 182.7 163.6 104.6 145.1 131.7 134.5 158.2 163.6 139.4 205.6 129.1 132.2 180.2 3.4 9.7 10.7 12.9 10.8 12.9 9.3 9.6 12.7 9.6 7.3 11.2 11.9 13.7 9.2 9.7 10.9 10.5 9.4 47.2 47.9 70.8 73.7 44.2 64.4 51.5 40.2 42.2 27.7 53.3 57.9 131.9 60.9 88.7 82.3 326.5 184.2 205.1 121.4 350.0 267.2 158.4 127.8 63.5 107.2 87.2 55.2 225.2 118.6 194.5 133.6 37.2 80.4 156.9 156.6 180.5 134.3 209.8 115.7 60.6 73.8 116.8 126.1 138.6 170.1 107.8 212.6 164.2 120.7 98.2 175.0 52.1 115.6 109.9 137.2 167.6 67.1 157.5 122.0 96.0 72.1 146.4 121.9 166.9 62.4 141.0 88.3 106.3 113.2 188.1 192.8 118.5 56.0 83.1 325.8 78.9 145.3 132.0 116.8 84.3 246.9 183.8 148.7 250.2 249.6 129.6 194.3 SGPP1 ENSG00000126821 "Sphingosine-1-phosphate phosphatase 1" Q9BX95 14 63684216-63728065 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 61.8;Oligodendrocytes: 60.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 43.8;U-698: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053149, HPA064908" Approved Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA053149: AB_2682057, HPA064908: AB_2797270" "unprognostic (1.57e-2)" "unprognostic (1.04e-2)" "unprognostic (5.40e-3)" "unprognostic (7.82e-2)" "unprognostic (9.09e-2)" "unprognostic (4.30e-2)" "unprognostic (6.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.64e-1)" "unprognostic (7.41e-2)" "unprognostic (1.51e-1)" "unprognostic (3.27e-1)" "unprognostic (8.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-3)" 7.9 10.6 5.3 6.0 6.0 3.0 6.4 5.8 7.9 6.4 3.6 7.0 3.8 7.4 6.2 4.9 5.7 5.5 4.9 5.3 5.9 15.9 19.5 6.9 13.3 6.6 6.2 5.8 12.7 10.2 5.6 12.0 6.6 7.4 5.3 4.1 4.8 4.0 4.2 3.8 8.8 4.8 7.3 9.3 5.5 5.4 5.8 5.8 5.8 2.6 12.9 5.8 6.8 8.0 19.7 6.2 3.0 8.6 10.7 9.9 35.9 15.7 10.9 9.6 10.7 2.7 10.9 43.8 4.5 8.0 8.0 20.3 4.8 9.3 15.3 17.3 5.7 4.0 3.4 4.4 13.1 7.3 12.2 7.3 14.7 8.4 13.2 9.7 4.6 8.2 2.3 1.2 14.1 7.3 8.6 0.1 2.1 3.2 13.1 2.1 8.4 3.5 15.2 9.7 1.8 5.0 11.0 10.2 8.4 9.2 13.3 2.6 5.2 13.2 9.1 9.5 7.9 10.1 6.5 57.4 9.7 0.0 5.8 6.9 0.2 1.7 0.5 1.4 0.5 1.8 0.5 0.3 0.3 0.4 0.8 0.6 0.2 0.3 2.1 0.1 1.3 0.3 5.3 6.0 5.8 7.9 5.3 5.9 6.6 6.2 6.6 7.3 5.8 8.0 5.3 12.8 16.2 22.2 22.6 9.7 6.1 4.1 8.0 4.0 9.4 5.2 3.8 24.3 3.2 51.5 0.0 23.4 10.9 11.9 0.0 6.0 2.4 6.3 12.1 6.5 18.6 9.7 32.6 9.1 27.0 12.8 3.1 10.1 11.4 5.0 6.1 43.6 23.7 10.1 38.5 10.2 2.0 61.8 20.1 1.2 6.2 18.6 17.8 21.5 6.8 8.2 2.1 31.7 60.0 13.2 13.5 17.0 5.7 8.1 3.2 22.7 2.6 5.4 6.6 8.1 11.3 7.4 3.5 4.6 13.5 33.0 10.4 10.3 10.3 5.6 SH2B2 APS ENSG00000160999 "SH2B adaptor protein 2" 7 102285091-102321711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 37.3" "Cell type enhanced" "Detected in many" "B-cells: 31.4;Extravillous trophoblasts: 67.0;Plasma cells: 30.0;Syncytiotrophoblasts: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4" "Group enriched" "Detected in many" 6 "B-cells: 3.4;granulocytes: 1.8;monocytes: 1.6" "Cell line enhanced" "Detected in many" "Daudi: 64.2;Karpas-707: 60.7;RPMI-8226: 46.7;U-266/70: 56.1;U-266/84: 106.7;U-698: 88.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051131 Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Cytosol "HPA051131: AB_2681354" "unprognostic (2.01e-2)" "unprognostic (4.00e-1)" "unprognostic (2.43e-2)" "unprognostic (7.32e-3)" "unprognostic (4.65e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-3)" "unprognostic (2.42e-1)" "unprognostic (3.65e-1)" "unprognostic (1.29e-1)" "unprognostic (8.29e-2)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.99e-7)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "unprognostic (2.02e-3)" "unprognostic (3.42e-2)" 5.4 1.8 6.3 5.8 4.9 3.6 3.6 4.3 5.3 4.6 1.3 2.6 2.2 4.5 0.3 1.9 4.6 1.5 2.2 3.9 9.3 6.0 1.8 5.7 10.7 10.6 11.2 1.9 1.9 1.0 3.0 1.8 7.0 4.4 0.5 0.8 2.8 0.7 37.3 3.6 5.5 0.9 7.1 14.5 2.4 3.4 10.4 0.8 4.5 13.8 5.5 4.0 3.4 3.5 3.7 2.8 3.0 6.6 0.7 0.3 27.6 1.3 0.5 0.8 0.6 0.8 0.6 64.2 6.4 0.5 2.8 3.7 0.7 0.9 0.3 8.1 2.8 0.0 1.7 0.6 0.6 0.5 2.2 0.6 0.9 0.5 0.2 1.1 0.2 1.6 0.4 60.7 1.3 6.9 0.3 11.5 7.0 2.3 11.5 8.1 3.3 46.7 2.1 1.0 3.2 11.4 2.3 5.6 1.6 2.3 1.0 8.4 0.2 1.0 6.2 11.0 1.3 56.1 106.7 88.3 3.9 2.3 1.5 0.0 0.3 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.3 3.4 0.0 0.0 1.8 0.0 0.6 0.0 0.0 0.0 6.3 4.9 4.3 5.3 3.9 9.3 10.6 11.2 7.0 7.1 10.4 3.5 5.6 0.0 0.0 6.2 31.4 2.5 2.5 0.0 1.8 6.8 3.4 2.9 1.1 1.5 0.0 0.0 0.0 9.3 2.9 0.8 0.0 0.2 0.4 3.8 2.4 7.3 1.8 0.4 2.2 0.0 67.0 2.0 1.1 5.4 0.0 1.0 2.2 0.8 7.8 5.0 4.8 0.6 0.0 14.1 17.6 2.0 0.6 15.1 7.2 2.8 6.0 9.2 1.0 1.0 0.5 0.1 0.5 0.4 30.0 5.7 0.1 13.0 0.0 1.4 0.0 6.6 2.0 1.1 15.8 0.6 1.6 58.1 1.3 0.4 1.3 2.2 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SKAP2 "RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R" ENSG00000005020 "Src kinase associated phosphoprotein 2" O75563 7 26667068-26995239 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 313.5;Kupffer cells: 192.2;Late spermatids: 354.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 149.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005560, HPA024045" Enhanced Supported Nucleoplasm,Cytosol NA NA 1000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA005560: AB_2667360, HPA024045: AB_2671416" "unprognostic (8.52e-2)" "unprognostic (5.57e-2)" "unprognostic (3.76e-1)" "unprognostic (5.62e-2)" "unprognostic (7.91e-3)" "unprognostic (1.30e-1)" "unprognostic (1.07e-3)" "unprognostic (4.15e-3)" "unprognostic (1.82e-1)" "unprognostic (1.41e-2)" "unprognostic (1.26e-2)" "unprognostic (3.80e-2)" "unprognostic (1.94e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.12e-1)" "unprognostic (3.51e-2)" 32.1 24.0 6.6 30.1 7.3 21.2 16.3 5.9 7.6 9.8 4.3 23.2 15.9 5.1 17.7 13.7 13.6 14.1 4.5 7.3 8.4 27.9 11.9 25.5 32.0 16.0 8.3 18.8 6.0 26.9 4.0 8.0 15.3 9.0 21.9 4.0 5.4 11.9 6.6 10.9 21.0 13.0 19.4 36.3 12.5 15.7 9.3 11.4 7.2 3.2 30.0 25.5 9.2 26.0 38.1 19.8 2.0 48.5 9.0 7.4 12.0 15.2 22.5 7.4 18.4 15.8 149.4 29.2 65.2 28.9 54.1 20.2 26.9 15.5 15.6 16.8 43.0 32.3 5.3 20.9 11.9 60.2 109.0 32.3 14.2 21.6 29.2 1.3 45.4 0.0 17.5 14.8 29.6 7.0 0.1 30.2 1.7 33.9 19.3 38.8 4.7 2.3 90.2 29.4 23.7 0.9 27.6 14.8 20.9 10.9 20.4 31.2 67.0 12.2 0.4 41.2 15.9 23.1 31.7 50.8 29.3 76.3 48.0 28.7 33.9 55.8 9.6 42.1 13.2 26.3 5.2 7.8 26.4 21.5 1.2 7.0 100.9 23.5 53.7 33.8 10.1 20.0 6.6 7.3 5.9 7.6 7.3 8.4 16.0 8.3 15.3 19.4 9.3 26.0 93.0 19.2 28.3 9.4 98.9 26.5 38.7 9.9 42.7 12.5 29.5 27.2 5.3 2.8 12.4 23.9 12.5 13.4 101.2 51.4 64.6 8.3 313.5 20.1 1.8 50.5 43.1 54.7 76.1 23.1 22.7 34.5 9.7 19.9 53.2 11.1 110.7 10.8 91.4 5.0 36.0 65.2 34.6 192.2 58.9 354.2 9.0 149.4 19.6 119.0 115.4 12.3 63.8 3.0 15.9 19.4 37.6 10.9 29.9 18.3 54.4 103.1 20.2 12.8 0.0 11.5 33.5 26.7 45.0 38.1 43.3 18.6 36.4 41.8 48.8 35.1 SLC12A6 "ACCPN, KCC3" ENSG00000140199 "Solute carrier family 12 member 6" Q9UHW9 15 34229784-34338060 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" Neuropathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 15.2;neutrophil: 23.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 23.4" "Cell line enhanced" "Detected in many" "HaCaT: 44.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034563 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA034563: AB_10603887" "unprognostic (3.53e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (3.60e-1)" "unprognostic (3.55e-2)" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (2.88e-1)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (6.58e-2)" "unprognostic (1.83e-1)" "prognostic favorable (3.33e-6)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (3.87e-2)" "unprognostic (1.41e-1)" 6.4 4.0 5.9 11.5 7.4 26.8 5.5 7.2 7.9 11.9 2.5 5.5 7.3 5.2 7.0 18.8 4.6 5.2 7.3 6.5 7.3 15.9 3.9 9.1 10.1 8.9 7.3 4.2 3.5 3.1 5.6 4.3 9.3 3.5 6.1 31.1 6.4 3.8 10.6 7.6 9.1 4.9 6.6 12.9 6.7 25.9 7.7 15.5 9.0 10.9 11.6 8.3 17.6 8.4 4.4 5.2 3.1 4.7 10.0 11.4 2.4 5.9 15.1 4.9 7.1 3.1 7.2 3.1 5.9 7.2 4.3 44.0 7.9 5.3 5.8 1.2 5.1 24.6 14.0 7.0 6.4 14.5 24.6 6.9 9.1 14.1 29.1 10.9 14.9 6.8 5.4 6.8 6.7 1.6 1.6 11.0 2.4 3.8 5.7 7.1 5.5 3.3 5.5 11.2 7.2 5.0 7.1 0.2 1.5 7.1 2.8 4.8 9.4 5.9 4.2 21.0 1.4 6.4 6.8 1.9 6.6 10.5 2.2 15.2 1.4 2.6 0.6 1.8 0.4 1.4 0.9 0.9 0.9 2.4 1.6 1.4 23.4 0.7 0.8 1.0 3.2 1.0 5.9 7.4 7.2 7.9 6.5 7.3 8.9 7.3 9.3 6.6 7.7 8.4 16.4 22.4 21.0 30.0 32.0 1.1 4.5 1.5 7.4 15.3 5.2 4.3 8.7 5.7 4.2 5.5 85.5 3.2 11.5 8.6 0.0 5.6 15.6 9.8 7.4 17.7 6.7 35.9 47.7 4.7 1.6 7.0 17.9 22.4 5.1 8.4 16.1 7.5 13.2 8.4 52.0 7.0 2.0 37.1 3.8 8.3 8.1 25.6 0.0 50.6 34.5 8.7 15.5 40.7 58.4 13.1 9.7 8.6 29.9 6.5 18.3 16.4 4.2 56.6 19.7 7.0 4.0 39.9 21.2 14.8 0.9 1.1 18.0 4.1 7.4 43.6 SMARCB1 "BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838009 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165" "unprognostic (2.15e-1)" "unprognostic (5.62e-2)" "unprognostic (6.60e-3)" "unprognostic (1.63e-2)" "unprognostic (4.01e-3)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.52e-4)" "unprognostic (4.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.10e-2)" "unprognostic (4.43e-3)" "prognostic favorable (1.14e-6)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (7.04e-2)" 35.9 46.4 2.3 6.9 2.5 3.3 40.3 4.1 10.0 51.5 2.7 40.9 8.1 51.4 0.4 51.0 40.4 2.2 44.0 2.3 2.3 47.0 36.9 32.3 5.8 4.3 2.7 63.1 43.9 1.2 48.0 1.2 2.7 36.6 1.1 25.3 44.1 0.6 48.1 50.1 51.7 0.6 2.2 51.7 40.4 68.3 2.3 3.5 41.3 1.8 1.5 37.5 40.9 2.9 2.4 1.6 28.2 2.6 2.7 0.7 5.8 9.2 2.7 2.7 4.3 3.4 2.6 24.2 7.9 1.2 2.9 4.4 6.9 4.6 4.5 4.1 10.5 20.1 3.2 2.1 3.0 21.7 5.6 1.6 3.4 3.2 6.9 1.4 1.4 3.0 5.6 12.9 1.7 6.1 17.6 5.0 8.6 7.2 5.7 11.0 23.1 10.8 2.3 4.5 13.4 10.1 2.2 0.6 17.9 14.8 2.2 3.3 2.2 2.4 9.8 3.8 2.7 13.8 14.3 17.7 1.8 11.3 6.8 7.1 12.8 6.4 4.4 13.4 6.4 24.4 5.5 5.7 12.0 9.2 4.5 3.0 1.1 9.8 16.8 13.3 10.4 8.1 2.3 2.5 4.1 10.0 2.3 2.3 4.3 2.7 2.7 2.2 2.3 2.9 33.6 6.4 8.6 17.0 120.2 50.2 73.3 85.1 51.2 55.4 42.9 49.1 6.1 47.1 37.4 47.8 20.9 120.6 61.8 36.6 84.1 94.6 42.6 40.9 54.9 37.4 71.8 57.8 14.1 77.1 228.1 46.2 41.8 41.1 34.8 112.2 41.0 20.3 76.1 67.3 18.4 54.6 99.7 23.0 41.7 18.9 35.8 36.5 56.9 15.9 51.2 92.4 45.3 17.1 18.1 74.7 53.1 32.0 139.6 74.4 41.9 86.4 28.5 49.6 19.7 47.7 62.8 138.9 163.3 64.5 53.0 160.1 42.0 96.8 65.4 65.1 SNX10 ENSG00000086300 "Sorting nexin 10" Q9Y5X0 7 26291862-26374383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 285.7;Hofbauer cells: 148.7;Kupffer cells: 215.5;Macrophages: 166.5;monocytes: 152.3;Muller glia cells: 310.5;Proximal tubular cells: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 336.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 103.1;U-937: 87.3;WM-115: 297.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015605, HPA064782" Approved Supported Nucleoplasm,Nucleoli,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Microtubules" Nucleoli "HPA015605: AB_1857342, HPA064782: AB_2685349" "unprognostic (6.42e-2)" "unprognostic (2.72e-3)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.92e-2)" "unprognostic (2.48e-3)" "unprognostic (4.51e-2)" "unprognostic (4.87e-1)" "unprognostic (9.36e-2)" "unprognostic (1.59e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (8.06e-5)" "unprognostic (1.12e-2)" "unprognostic (3.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.50e-1)" 23.7 14.5 26.4 34.7 27.8 42.1 11.0 17.6 45.9 4.5 6.1 5.6 4.1 9.0 1.1 2.9 3.0 8.8 1.8 30.2 42.2 37.8 69.1 41.2 36.9 29.1 28.2 1.1 7.8 1.3 4.7 10.9 40.3 3.5 6.4 47.1 1.7 2.1 1.0 1.4 6.2 9.5 18.6 42.1 3.9 5.1 32.0 15.8 2.9 2.7 24.8 10.9 1.6 26.8 55.8 5.0 0.2 10.1 0.1 0.0 57.8 0.0 3.9 0.1 0.0 0.5 18.4 24.0 41.4 0.0 36.2 1.7 13.5 3.6 0.0 33.3 12.4 2.5 0.4 36.3 0.1 52.2 8.9 0.6 5.4 0.0 4.2 0.1 0.8 30.7 1.5 0.3 0.0 9.7 22.2 54.3 15.3 0.9 5.1 0.1 0.1 1.3 103.1 12.0 22.5 7.1 11.7 8.5 62.7 18.1 15.2 72.6 0.3 0.1 12.2 0.2 13.7 17.9 15.5 16.4 0.5 87.3 297.4 55.9 144.7 3.7 18.6 158.5 18.2 82.3 13.2 16.4 101.2 71.7 6.9 12.0 336.7 47.7 162.5 37.0 29.6 70.0 26.4 27.8 17.6 45.9 30.2 42.2 29.1 28.2 40.3 18.6 32.0 26.8 3.3 3.2 14.7 6.8 63.4 5.4 1.2 0.7 1.8 20.3 17.6 9.5 1.8 34.3 4.4 23.9 2.1 14.9 18.6 2.5 285.7 66.0 1.3 2.1 40.7 7.6 9.5 19.1 63.1 27.1 111.8 3.4 0.0 2.3 31.1 2.9 2.2 109.8 148.7 35.3 53.4 3.3 0.0 215.5 130.3 2.1 1.2 166.5 8.8 19.7 152.3 310.5 33.0 7.1 8.5 14.1 1.5 0.0 8.0 4.4 4.5 204.9 0.8 23.2 0.0 0.7 4.7 7.1 29.5 0.8 3.0 28.7 31.6 0.9 8.7 1.3 SP100 ENSG00000067066 "SP100 nuclear antigen" P23497 2 230415942-230545606 "Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 255.0" "Low region specificity" "Detected in all" "HPA016707, HPA017384" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" "Nuclear bodies" Nucleoplasm "HPA016707: AB_1857398, HPA017384: AB_1857399" "unprognostic (8.04e-3)" "unprognostic (1.08e-2)" "unprognostic (3.34e-2)" "unprognostic (1.86e-3)" "unprognostic (5.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (6.25e-3)" "unprognostic (5.32e-3)" "unprognostic (1.11e-2)" "unprognostic (3.17e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.96e-2)" "unprognostic (1.48e-2)" "unprognostic (2.33e-2)" "unprognostic (3.25e-2)" 66.3 53.1 11.0 65.5 12.3 189.2 53.8 11.3 17.9 42.4 20.7 46.1 46.1 35.1 30.8 29.4 34.9 55.9 52.9 10.9 14.0 46.0 60.9 72.4 94.3 19.6 14.3 44.3 41.1 10.5 18.3 54.5 16.7 34.9 36.1 2.5 72.7 33.0 24.3 35.7 60.4 38.7 16.2 78.8 47.9 9.2 16.5 54.2 41.0 32.1 81.6 56.1 37.1 17.1 56.9 16.9 0.8 7.5 80.8 123.2 13.3 70.3 151.0 162.4 255.0 10.6 67.9 22.9 57.0 77.0 103.0 25.9 0.8 66.6 120.7 55.2 1.9 41.8 27.9 24.0 120.0 47.3 51.4 105.6 38.8 79.8 71.4 120.2 125.1 18.9 23.9 37.9 61.7 15.9 32.0 57.6 2.4 25.6 25.6 24.4 40.7 18.2 45.9 45.3 0.4 0.7 30.0 9.5 130.3 2.8 9.1 48.3 140.3 78.7 21.4 49.4 41.8 50.3 16.0 59.8 71.6 54.8 38.1 149.7 84.4 115.8 116.3 74.9 93.9 152.0 113.0 102.4 64.6 160.5 107.5 95.3 284.6 119.8 106.0 67.0 116.0 110.1 11.0 12.3 11.3 17.9 10.9 14.0 19.6 14.3 16.7 16.2 16.5 17.1 171.9 153.8 56.6 0.3 236.6 70.7 71.2 96.5 49.5 0.6 31.2 36.7 72.3 42.9 74.4 33.1 2.1 32.9 150.6 50.5 43.0 102.9 4.7 61.6 58.3 122.7 9.0 66.9 0.6 105.5 69.4 77.9 46.4 58.9 56.8 39.3 73.5 34.5 81.0 0.0 0.7 32.5 63.1 72.9 70.9 4.8 46.6 104.1 71.2 140.5 114.3 0.2 128.8 4.5 4.8 89.7 56.9 52.6 95.6 74.2 72.8 45.4 68.4 0.8 39.5 61.2 65.9 0.8 1.1 28.4 68.2 16.1 151.5 74.0 25.2 73.7 SP110 "IFI41, IFI75" ENSG00000135899 "SP110 nuclear body protein" Q9HB58 2 230165186-230225729 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.7" "Cell type enhanced" "Detected in many" "B-cells: 141.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 99.3" "Low region specificity" "Detected in all" HPA058554 Supported Nucleoplasm No No "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA058554: AB_2683754" "unprognostic (9.72e-2)" "unprognostic (1.15e-2)" "unprognostic (5.02e-2)" "unprognostic (8.33e-4)" "unprognostic (2.93e-1)" "unprognostic (1.80e-1)" "unprognostic (6.65e-2)" "unprognostic (9.44e-2)" "unprognostic (9.68e-2)" "unprognostic (1.46e-2)" "unprognostic (4.11e-3)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.38e-1)" "unprognostic (2.66e-2)" "unprognostic (2.99e-3)" "unprognostic (9.50e-3)" 14.0 7.3 8.4 38.5 10.3 29.8 11.8 9.4 10.8 11.6 11.5 12.6 11.9 10.5 7.9 9.2 9.6 18.0 8.1 8.1 10.3 11.9 14.8 21.0 53.7 15.3 10.9 16.5 7.9 9.7 5.3 17.5 11.6 9.6 14.0 2.0 17.0 7.6 5.7 7.8 17.6 13.4 12.1 49.8 12.9 3.1 10.9 35.7 7.4 8.4 50.1 18.9 9.3 12.3 8.3 4.4 2.7 4.7 14.2 23.6 8.3 14.8 30.8 70.3 99.3 0.2 12.7 34.5 13.8 15.8 67.0 5.1 9.0 23.0 25.7 30.5 6.0 14.9 6.2 8.9 14.5 22.1 17.1 32.7 11.8 20.8 27.4 13.2 25.3 23.6 5.3 12.1 20.6 4.9 33.0 43.5 8.6 4.2 5.1 20.1 25.4 12.8 56.2 11.1 0.5 5.7 5.7 12.7 32.7 0.9 9.6 18.5 18.8 12.9 7.9 3.2 7.5 12.9 4.6 16.2 14.4 20.6 10.7 92.2 49.7 124.4 55.2 85.8 47.8 142.8 53.5 50.5 44.1 135.8 54.1 58.7 268.6 56.9 143.4 84.4 70.7 48.5 8.4 10.3 9.4 10.8 8.1 10.3 15.3 10.9 11.6 12.1 10.9 12.3 77.8 44.8 23.8 17.3 141.7 9.9 5.2 25.7 16.5 0.4 21.6 19.3 3.7 7.2 19.6 11.0 0.0 3.8 84.0 17.0 13.7 19.9 5.2 17.2 21.3 28.6 6.7 9.7 1.1 28.5 12.7 22.8 9.2 20.1 38.0 21.2 26.4 6.2 26.9 0.0 2.1 11.4 73.2 47.4 25.8 4.2 11.8 62.3 19.6 42.2 56.7 9.7 59.8 19.6 18.2 26.0 11.6 10.1 35.7 3.5 10.7 14.4 21.0 4.9 6.6 8.6 16.2 4.8 2.3 9.8 10.1 4.7 68.8 23.5 6.1 3.0 SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.6;lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" "B-cells: 149.9;dendritic cells: 37.4;NK-cells: 50.4;Plasma cells: 77.2;T-cells: 62.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 31.1;HDLM-2: 52.4;Karpas-707: 25.2;RPMI-8226: 16.3" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Mitochondria "HPA006162: AB_1857403, HPA067493: AB_2685851" "unprognostic (8.15e-3)" "unprognostic (2.25e-3)" "unprognostic (3.90e-3)" "unprognostic (5.72e-4)" "unprognostic (5.66e-2)" "unprognostic (3.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-2)" "unprognostic (2.88e-1)" "unprognostic (1.20e-9)" "unprognostic (9.12e-2)" "unprognostic (8.50e-2)" "unprognostic (3.66e-1)" "unprognostic (9.30e-3)" 1.7 0.8 0.7 25.0 0.8 6.6 1.2 0.8 1.6 0.6 1.0 3.5 2.9 0.9 0.8 0.9 0.7 2.9 0.6 0.8 1.1 0.9 1.6 4.4 54.6 1.8 1.2 0.4 0.3 0.2 0.6 1.2 1.5 0.9 3.9 1.0 2.6 0.5 0.2 1.6 15.6 1.0 1.3 27.8 5.1 1.5 2.1 6.8 1.3 0.1 55.8 4.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 2.4 0.0 0.3 31.1 0.0 0.0 5.2 0.0 0.0 0.1 1.8 52.4 0.0 0.0 0.0 0.6 0.2 4.4 0.1 0.5 0.0 0.5 0.6 0.4 0.0 0.3 0.0 25.2 0.6 0.0 0.0 1.5 1.3 0.0 0.0 0.1 2.8 16.3 8.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.1 0.3 1.3 0.0 0.0 9.2 4.0 1.1 2.2 0.7 0.0 0.1 3.5 12.0 23.1 7.3 25.6 97.5 22.8 25.3 8.3 71.0 11.5 15.0 33.4 15.1 10.6 0.5 22.5 10.6 0.7 0.8 0.8 1.6 0.8 1.1 1.8 1.2 1.5 1.3 2.1 1.5 1.6 0.0 2.3 3.9 149.9 0.9 0.0 0.2 0.0 0.7 0.3 0.5 0.5 0.0 0.8 0.0 8.4 0.1 37.4 0.1 0.0 0.0 17.2 0.5 0.2 1.1 0.0 9.7 5.0 0.0 0.2 0.8 1.5 0.1 0.0 0.2 2.2 0.9 11.4 0.0 5.0 0.1 0.0 8.4 8.6 4.8 0.0 13.2 7.2 26.2 13.7 0.5 50.4 2.5 2.8 0.1 0.1 1.2 77.2 0.1 0.0 0.4 2.4 1.7 0.0 0.2 1.0 1.2 0.4 0.7 1.1 0.3 62.1 0.3 0.2 0.2 STAP1 "BRDG1, STAP-1" ENSG00000035720 "Signal transducing adaptor family member 1" Q9ULZ2 4 67558727-67607337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 51.0" "Group enriched" "Detected in some" 5 "B-cells: 60.8;granulocytes: 80.8;Ionocytes: 65.1;Plasma cells: 147.2" "Cancer enriched" "Detected in many" 7 "renal cancer: 13.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 88.1;naive B-cell: 107.8" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Daudi: 185.4;U-698: 83.2" "Region enriched" "Detected in single" 5 "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA038529 Enhanced Uncertain Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "HPA038529: AB_10673011" "unprognostic (1.14e-4)" "unprognostic (1.49e-3)" "unprognostic (2.30e-2)" "unprognostic (2.17e-1)" "unprognostic (1.63e-3)" "unprognostic (6.30e-4)" "unprognostic (1.95e-3)" "unprognostic (6.95e-3)" "unprognostic (5.18e-2)" "unprognostic (6.38e-3)" "unprognostic (1.47e-1)" "unprognostic (8.43e-3)" "unprognostic (3.11e-2)" "unprognostic (1.49e-2)" "unprognostic (4.69e-2)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" 0.4 0.1 0.0 15.5 0.0 5.8 0.8 0.0 0.0 0.3 0.0 2.3 1.8 0.6 1.9 0.7 0.1 1.4 0.2 0.5 0.0 9.2 0.4 1.4 40.8 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.9 2.3 0.0 1.3 2.8 0.1 0.1 8.1 0.4 0.0 16.0 2.3 2.7 0.0 6.4 0.4 0.0 51.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 185.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 24.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 83.2 0.0 24.7 0.0 5.3 0.1 24.3 0.9 0.1 1.9 88.1 2.0 0.8 1.2 107.8 7.9 0.2 1.0 38.9 0.1 5.2 0.4 4.7 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.7 0.0 60.8 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.7 5.5 0.0 0.0 5.8 0.0 9.8 0.0 13.0 0.1 0.0 0.6 0.0 2.5 0.3 0.0 0.0 0.1 0.0 0.0 80.8 0.0 0.4 0.0 0.8 0.0 0.2 0.1 65.1 0.3 0.7 7.1 0.3 1.2 16.0 0.0 0.2 0.0 6.2 0.0 0.3 0.0 0.0 0.4 147.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 3.7 0.2 0.1 0.1 0.0 4.3 0.1 0.0 0.2 STX7 ENSG00000079950 "Syntaxin 7" O15400 6 132445867-132513198 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 53.6;classical monocyte: 51.6;eosinophil: 49.1;intermediate monocyte: 58.1;memory B-cell: 85.9;myeloid DC: 61.6;naive B-cell: 106.8;neutrophil: 83.2;non-classical monocyte: 61.6;plasmacytoid DC: 73.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001467, CAB062564" Enhanced Supported Lysosomes NA NA 380000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 57: B-cells - Immune response" Lysosomes "CAB062564: AB_2665605, HPA001467: AB_1857623" "unprognostic (1.91e-3)" "unprognostic (1.06e-3)" "unprognostic (2.67e-2)" "unprognostic (7.95e-3)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (4.52e-2)" "unprognostic (4.46e-1)" "unprognostic (4.19e-2)" "unprognostic (2.84e-1)" "unprognostic (2.79e-1)" "unprognostic (1.65e-3)" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "unprognostic (1.67e-1)" "unprognostic (8.42e-2)" 35.1 17.7 17.6 41.5 20.4 21.6 21.2 20.8 21.1 22.5 11.5 25.1 37.2 27.2 12.1 33.7 22.1 33.5 36.0 19.8 21.0 51.1 18.3 31.5 76.3 23.2 22.2 30.9 14.3 20.5 7.4 42.9 22.4 19.5 29.1 15.9 20.6 25.9 23.1 20.4 37.9 29.2 21.2 45.5 28.3 8.2 18.0 17.7 30.8 22.7 71.8 26.2 16.6 29.3 17.5 17.5 28.7 20.6 56.4 49.9 22.6 33.9 34.7 34.4 49.3 30.9 28.9 87.6 32.7 41.1 51.0 22.8 25.5 31.2 46.6 30.2 30.4 33.1 14.6 33.0 44.6 22.8 24.2 28.6 28.5 35.3 31.6 46.5 37.8 19.2 36.1 30.7 39.8 24.8 10.4 18.2 11.0 25.4 20.2 24.6 22.5 25.5 57.9 20.4 23.5 7.1 15.3 24.9 91.9 42.2 17.0 21.2 66.4 20.1 20.5 44.1 36.6 29.1 18.2 37.2 28.3 17.9 23.2 53.6 51.6 49.1 10.8 58.1 4.4 85.9 8.0 7.7 61.6 106.8 5.7 6.8 83.2 9.5 61.6 73.9 12.8 31.3 17.6 20.4 20.8 21.1 19.8 21.0 23.2 22.2 22.4 21.2 18.0 29.3 37.7 70.5 36.5 34.0 151.6 42.1 23.5 33.8 26.7 26.8 26.7 22.2 51.0 85.8 33.1 42.3 2.1 85.7 111.5 50.8 64.6 56.9 1.2 27.9 33.4 38.3 13.2 57.9 61.3 30.9 54.5 34.1 42.3 28.0 40.6 25.9 43.5 19.4 177.6 37.0 60.6 39.8 38.7 99.4 78.7 2.1 30.7 109.6 133.4 109.6 110.7 25.7 54.6 44.2 77.9 57.6 63.1 46.3 37.3 24.7 113.5 155.0 43.9 16.5 39.5 30.2 38.6 2.7 17.6 36.2 41.2 55.4 24.4 17.9 28.4 24.9 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.3;Hofbauer cells: 73.1;Kupffer cells: 96.7;Macrophages: 95.2;Microglial cells: 114.3;monocytes: 92.5;Plasma cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 125.8;HEL: 72.8;HL-60: 101.6;HMC-1: 64.1;REH: 84.4;THP-1: 76.8;U-698: 58.8;U-937: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.4 4.6 4.1 42.5 4.1 50.9 6.8 4.5 4.9 7.7 4.2 20.1 30.8 4.1 16.1 17.5 17.0 12.9 2.9 3.8 5.0 11.2 4.5 20.6 61.8 7.1 5.8 1.7 9.1 87.6 2.4 12.0 7.0 3.8 20.5 0.7 8.4 4.2 1.0 9.9 36.3 9.3 6.6 40.3 19.1 6.9 7.1 49.7 25.6 2.4 73.8 17.5 8.3 9.8 22.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 14.3 125.8 3.5 0.0 4.2 19.1 2.7 10.2 0.0 0.0 17.0 72.8 0.0 0.0 0.0 101.6 64.1 0.0 14.0 0.0 1.4 0.0 0.0 15.5 2.0 9.9 0.0 15.4 0.1 44.4 0.7 47.0 0.0 84.4 0.1 34.6 2.6 18.6 6.4 5.7 0.1 8.7 0.1 0.3 7.9 76.8 0.2 0.0 0.4 0.1 0.1 0.2 0.0 58.8 0.0 70.3 0.0 5.3 77.3 83.5 0.3 64.0 0.3 74.5 0.2 0.2 85.1 58.4 0.2 0.1 112.1 30.0 60.2 63.2 0.1 44.6 4.1 4.1 4.5 4.9 3.8 5.0 7.1 5.8 7.0 6.6 7.1 9.8 0.5 12.8 20.2 0.0 91.3 3.4 3.7 8.7 12.0 1.4 6.3 2.8 1.6 14.3 12.8 14.7 0.0 1.3 70.4 16.5 15.6 15.0 7.1 10.7 1.0 2.1 10.3 37.9 0.4 12.5 2.6 2.1 22.4 12.6 43.6 0.0 3.3 1.0 73.1 0.0 0.7 24.4 0.0 96.7 28.8 6.2 0.6 95.2 12.4 114.3 92.5 0.0 62.8 1.5 0.5 18.2 25.1 0.0 83.1 2.5 31.4 0.4 10.4 0.2 6.6 0.7 2.3 0.8 0.7 30.4 5.7 1.4 8.3 0.0 31.1 8.0 SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134532 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 72.9;Plasma cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 205.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favorable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" 29.2 40.3 19.3 37.1 25.6 31.0 27.6 23.2 21.4 30.7 26.7 29.2 26.1 29.1 38.8 28.4 30.6 19.7 25.3 18.6 21.2 24.5 117.5 27.0 60.9 27.9 25.6 30.9 90.9 35.0 38.2 26.2 24.6 28.5 29.0 18.7 55.9 30.3 34.2 29.3 39.4 25.9 22.8 51.2 39.4 24.3 23.4 18.3 43.4 19.0 81.1 25.8 24.8 25.9 32.4 40.6 24.0 32.5 59.8 33.8 23.8 32.8 33.5 40.9 28.8 22.2 55.0 181.0 43.8 42.4 53.8 48.8 26.4 33.3 33.6 28.4 20.0 28.6 46.8 50.2 72.3 43.3 49.6 43.3 59.0 36.1 81.0 36.4 27.0 19.0 36.4 90.1 24.3 47.9 19.1 31.2 26.1 33.6 28.0 31.9 20.3 74.0 25.7 31.5 15.6 32.0 30.4 74.1 53.3 21.0 55.4 28.2 25.9 28.3 18.6 51.2 22.4 178.1 134.2 205.9 38.1 21.8 32.3 16.8 7.4 14.0 7.4 4.7 6.5 21.9 5.2 6.9 4.4 22.6 3.7 3.9 7.0 3.5 4.7 18.4 5.3 6.6 19.3 25.6 23.2 21.4 18.6 21.2 27.9 25.6 24.6 22.8 23.4 25.9 11.5 16.0 21.4 11.1 43.5 17.6 6.9 13.8 12.0 10.7 21.0 15.5 4.0 22.8 20.8 11.0 33.3 14.5 16.4 23.1 1.9 13.6 6.6 14.2 16.2 11.3 8.4 13.2 9.6 18.9 16.5 14.2 17.9 22.1 1.3 10.1 15.0 72.9 15.1 13.5 9.5 33.6 16.2 15.3 13.2 4.1 20.5 10.8 12.4 9.4 10.5 11.0 13.4 13.0 15.8 18.2 11.7 13.2 90.5 14.9 14.0 7.7 15.1 18.7 13.1 11.9 10.7 19.3 13.2 9.7 16.1 42.8 11.7 13.6 18.6 13.8 TAF1A "SL1, TAFI48" ENSG00000143498 "TATA-box binding protein associated factor, RNA polymerase I subunit A" Q15573 1 222557902-222589933 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054334 Approved Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA054334: AB_2682453" "unprognostic (3.01e-1)" "prognostic unfavorable (9.26e-6)" "unprognostic (7.98e-2)" "unprognostic (9.59e-3)" "unprognostic (1.22e-1)" "unprognostic (8.98e-3)" "unprognostic (3.88e-3)" "unprognostic (3.10e-3)" "unprognostic (4.79e-2)" "unprognostic (2.93e-1)" "unprognostic (3.86e-3)" "unprognostic (2.25e-1)" "unprognostic (2.41e-4)" "unprognostic (8.43e-2)" "unprognostic (1.76e-1)" "unprognostic (2.35e-3)" "unprognostic (9.06e-2)" 3.0 3.4 2.0 4.8 2.1 2.7 3.2 2.3 2.3 3.0 1.6 2.0 2.5 4.1 3.0 2.6 2.8 2.7 1.9 1.7 2.8 2.1 1.8 2.8 6.5 2.4 2.0 6.8 1.9 1.9 2.5 4.4 2.3 3.2 2.6 4.0 2.0 2.7 1.2 2.1 2.4 2.5 2.1 4.4 3.4 6.4 2.1 4.4 5.1 1.3 5.6 5.3 2.5 3.0 13.8 7.3 19.5 6.8 6.6 5.8 17.2 9.1 7.0 10.8 13.2 7.8 14.8 12.6 17.4 3.2 8.6 13.7 13.1 5.6 15.2 8.3 9.9 7.5 6.3 7.5 7.4 18.2 3.3 3.0 6.0 12.1 15.4 5.1 4.5 8.7 23.4 5.6 14.9 5.0 21.6 13.0 39.5 15.8 21.0 13.2 39.1 12.2 4.5 7.3 11.1 23.1 14.0 8.1 10.1 9.9 4.6 9.1 6.1 10.9 10.9 19.4 23.2 6.8 6.6 16.5 9.7 11.7 14.7 1.8 1.5 2.1 3.2 2.5 4.7 5.2 2.8 2.9 1.5 7.4 3.3 4.1 0.3 3.0 2.5 5.3 2.5 1.7 2.0 2.1 2.3 2.3 1.7 2.8 2.4 2.0 2.3 2.1 2.1 3.0 3.1 0.0 1.1 6.5 8.6 8.5 6.4 3.9 6.8 10.2 3.1 3.6 1.5 2.8 1.9 3.7 6.2 7.2 4.6 2.4 1.9 2.9 2.5 3.0 6.1 2.7 1.2 3.8 5.2 0.7 6.7 6.0 4.1 3.0 1.3 7.7 1.1 2.0 4.4 6.7 7.1 3.0 0.0 3.8 1.0 1.3 5.6 4.7 0.0 3.7 2.7 3.8 2.1 8.0 8.0 1.3 1.8 2.2 4.4 8.0 0.9 1.3 2.6 8.5 6.6 4.5 4.3 11.5 12.1 4.9 2.8 5.9 4.7 4.2 3.2 8.8 TBC1D22A C22orf4 ENSG00000054611 "TBC1 domain family member 22A" Q8WUA7 22 46762617-47175699 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 252.9;Oligodendrocytes: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001173 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA001173: AB_1080212" "unprognostic (1.62e-1)" "unprognostic (5.90e-3)" "unprognostic (1.10e-1)" "unprognostic (4.79e-3)" "unprognostic (3.65e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (5.95e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.69e-1)" "unprognostic (9.17e-2)" "unprognostic (4.68e-2)" "unprognostic (4.93e-2)" "unprognostic (4.14e-1)" "unprognostic (1.09e-1)" "unprognostic (2.39e-1)" 13.4 12.3 10.5 14.4 9.9 10.4 11.8 9.0 10.5 11.8 7.9 12.5 14.9 10.5 6.8 18.1 12.1 9.3 12.9 10.4 9.2 13.3 11.0 12.7 19.4 11.3 11.5 9.8 14.7 12.0 11.2 12.0 10.7 9.3 9.5 4.9 14.1 7.8 17.9 17.6 15.0 7.6 9.8 19.1 14.8 7.3 11.0 14.7 12.3 11.3 18.4 11.0 12.3 11.4 19.1 13.0 8.1 9.9 11.6 16.1 9.9 12.8 17.2 14.3 15.3 14.8 14.5 16.6 13.9 19.5 8.9 20.7 7.0 20.0 9.9 7.2 19.6 9.5 11.1 28.6 17.7 20.9 7.4 18.9 23.0 9.8 13.6 17.2 23.7 10.4 6.2 17.4 13.1 9.8 9.3 10.7 8.0 17.9 14.6 11.8 9.5 17.9 16.7 9.7 6.6 12.3 11.8 4.5 20.1 10.0 10.5 13.7 19.5 10.9 15.3 11.5 8.2 11.5 3.9 10.5 27.0 10.6 6.9 2.5 10.7 6.3 6.4 15.5 6.0 11.6 5.9 6.1 12.5 13.0 3.9 4.3 15.5 5.5 18.6 6.1 10.2 6.6 10.5 9.9 9.0 10.5 10.4 9.2 11.3 11.5 10.7 9.8 11.0 11.4 20.3 25.6 18.3 81.0 47.0 6.4 12.1 21.1 21.6 18.6 9.9 7.9 8.6 14.3 20.2 7.3 18.8 24.4 22.7 27.9 11.7 25.8 13.9 20.1 14.2 19.0 3.6 13.5 82.0 23.5 19.6 12.2 39.3 14.5 17.1 13.3 23.2 7.9 33.1 21.9 94.2 16.2 18.3 23.0 16.7 3.5 9.9 32.7 10.6 252.9 39.4 13.7 29.9 76.9 113.2 30.2 25.2 11.7 28.8 10.5 39.4 19.8 15.0 27.3 13.1 12.3 11.8 7.9 10.5 18.5 8.0 29.0 22.7 12.7 18.4 11.8 TCL1A TCL1 ENSG00000100721 "TCL1 family AKT coactivator A" P56279 14 95709947-95714196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 267.6" "Group enriched" "Detected in some" 4 "B-cells: 282.5;dendritic cells: 210.3" "Cancer enriched" "Detected in many" 18 "testis cancer: 64.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 296 "memory B-cell: 874.7;naive B-cell: 2160.3;plasmacytoid DC: 1099.9" "Group enriched" "Detected in all" 350 "B-cells: 2160.3;dendritic cells: 1099.9" "Group enriched" "Detected in some" 142 "Daudi: 459.4;REH: 599.4;U-698: 616.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004045, HPA016604" Enhanced Enhanced "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB004045: AB_2179419, HPA016604: AB_1857859" "unprognostic (1.27e-3)" "unprognostic (3.12e-4)" "unprognostic (2.61e-4)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (4.75e-4)" "unprognostic (7.70e-2)" "unprognostic (9.67e-3)" "unprognostic (1.03e-1)" "unprognostic (3.35e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-2)" "unprognostic (2.64e-2)" "unprognostic (1.87e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (4.55e-1)" 1.0 0.1 0.1 34.4 0.1 20.3 0.2 0.1 0.1 0.1 0.0 2.4 0.8 0.8 0.6 0.5 0.1 3.6 0.6 0.1 0.1 0.4 0.4 1.0 267.6 0.1 0.1 0.1 0.3 0.0 0.0 0.8 0.2 0.3 2.0 0.0 4.0 0.0 0.1 0.4 14.2 0.3 0.0 56.7 3.4 7.7 0.1 19.1 1.1 0.0 216.0 2.7 0.1 0.3 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 459.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.6 0.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 599.4 0.3 0.8 0.0 0.0 0.2 0.2 0.4 0.7 0.1 0.3 0.1 1.0 1.0 0.2 2.8 0.6 0.2 0.5 3.9 616.2 0.2 0.1 0.1 4.6 1.4 1.8 0.5 0.5 1.3 874.7 0.9 0.4 2.2 2160.3 1.5 0.5 3.3 1.3 1.6 1099.9 1.2 92.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 1.3 0.0 282.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 210.3 0.6 0.0 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.2 0.0 0.3 0.0 0.9 0.6 2.8 0.0 0.0 2.7 0.0 3.1 0.0 0.0 0.0 0.2 0.4 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 28.7 60.2 0.0 0.0 0.0 2.7 0.0 0.3 0.0 TFEB "bHLHe35, TCFEB" ENSG00000112561 "Transcription factor EB" P19484 6 41683978-41736259 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Autophagy, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 97.4;Syncytiotrophoblasts: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 16.1;eosinophil: 16.9;intermediate monocyte: 16.3;memory B-cell: 34.2;myeloid DC: 14.7;naive B-cell: 22.6;neutrophil: 47.4;non-classical monocyte: 14.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 60.3;Daudi: 35.8;OE19: 53.1;U-698: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067082 Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Cytosol "HPA067082: " "unprognostic (3.63e-3)" "unprognostic (1.51e-3)" "unprognostic (1.75e-2)" "unprognostic (4.48e-3)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (4.22e-3)" "unprognostic (1.39e-2)" "unprognostic (4.13e-2)" "prognostic favorable (4.77e-4)" "unprognostic (2.12e-2)" "prognostic favorable (1.06e-5)" "unprognostic (1.44e-1)" "unprognostic (3.51e-2)" "unprognostic (2.46e-1)" "unprognostic (1.31e-2)" 14.3 10.7 18.3 16.7 29.9 8.3 15.0 24.0 23.5 13.4 9.6 25.7 5.8 11.1 1.5 14.8 12.8 7.7 37.1 18.1 19.7 26.7 11.6 18.2 26.1 30.9 27.7 6.5 12.9 17.8 31.3 14.5 25.8 23.4 4.3 2.2 21.2 7.0 89.9 17.9 34.6 5.7 22.5 57.2 14.4 2.6 25.4 5.0 22.9 41.5 17.2 19.6 15.6 39.9 3.5 3.2 0.6 12.3 3.8 2.5 60.3 5.3 6.9 3.4 2.7 6.9 2.7 35.8 6.8 3.5 2.9 8.7 2.4 4.9 1.0 28.3 4.1 0.1 8.8 12.8 6.8 1.0 4.3 0.7 9.8 4.9 2.6 6.9 4.1 3.3 4.1 7.4 1.0 1.8 2.3 1.2 0.1 53.1 1.6 24.3 0.1 5.0 7.5 2.6 12.8 4.3 4.7 10.5 1.0 3.4 2.3 19.5 7.1 1.5 3.1 0.1 3.0 15.7 2.3 42.1 2.6 15.3 0.9 0.3 16.1 16.9 3.8 16.3 0.9 34.2 1.5 1.8 14.7 22.6 0.4 1.5 47.4 1.7 14.1 2.9 0.6 8.7 18.3 29.9 24.0 23.5 18.1 19.7 30.9 27.7 25.8 22.5 25.4 39.9 14.5 9.6 9.3 10.1 36.7 14.1 8.2 14.8 5.2 6.1 5.7 5.6 19.2 10.0 6.0 12.9 12.5 50.7 13.8 16.3 21.5 3.7 1.1 11.4 2.6 12.2 13.2 3.2 6.3 6.9 8.3 6.9 6.1 8.0 1.3 0.5 6.4 4.2 26.8 26.9 7.9 10.2 26.4 22.8 13.3 4.2 3.4 19.6 0.0 17.8 20.0 18.4 22.6 11.1 97.4 10.6 18.0 10.9 16.0 7.1 14.1 3.7 7.4 5.2 6.6 13.1 7.8 0.9 1.0 6.4 14.5 120.4 9.1 0.8 8.8 6.3 TGIF2 ENSG00000118707 "TGFB induced factor homeobox 2" Q9GZN2 20 36573488-36593950 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053786, HPA064522" Enhanced Nucleoplasm,Centrosome NA NA "Cluster 38: Basophils - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: NES - Nervous system development" "Cluster 57: B-cells - Immune response" Nucleoplasm Centrosome "HPA053786: AB_2682261, HPA064522: " "unprognostic (1.42e-2)" "unprognostic (8.27e-2)" "unprognostic (2.80e-1)" "unprognostic (2.10e-3)" "unprognostic (4.50e-2)" "unprognostic (2.10e-1)" "unprognostic (7.19e-2)" "unprognostic (4.88e-2)" "unprognostic (2.70e-2)" "unprognostic (1.77e-1)" "unprognostic (6.73e-2)" "unprognostic (1.51e-1)" "unprognostic (3.75e-2)" "unprognostic (8.53e-2)" "unprognostic (1.22e-1)" "unprognostic (8.79e-3)" "unprognostic (1.14e-2)" 7.5 5.9 3.9 12.4 4.0 7.6 10.2 3.6 3.8 10.5 8.6 8.6 4.8 22.0 4.4 5.7 24.2 8.6 6.3 3.7 3.9 9.2 9.3 8.6 16.9 5.7 4.6 13.7 15.1 13.2 3.0 11.6 4.6 9.0 5.5 5.2 10.2 7.8 2.1 5.8 8.3 18.6 4.8 14.6 7.0 11.4 4.9 17.8 8.5 3.7 18.7 9.5 6.6 4.5 16.1 4.2 45.0 52.3 6.2 5.6 16.1 8.9 10.3 21.3 15.5 22.9 20.5 42.5 23.2 9.2 9.7 16.4 36.1 23.6 20.8 20.0 13.2 53.5 10.6 30.5 9.6 23.6 12.7 9.1 15.0 4.8 16.4 19.1 20.9 20.6 26.1 27.3 10.4 22.8 38.8 43.6 37.1 23.0 11.1 33.2 52.7 24.0 13.8 10.7 13.5 40.0 3.1 23.3 23.1 34.8 28.7 51.2 15.6 3.7 13.7 0.3 17.2 29.6 11.9 40.3 0.3 27.2 16.6 16.0 5.0 1.6 4.0 4.3 4.4 7.2 3.6 4.1 6.7 4.9 6.0 5.1 2.0 3.8 3.0 6.7 3.8 3.8 3.9 4.0 3.6 3.8 3.7 3.9 5.7 4.6 4.6 4.8 4.9 4.5 11.5 9.6 8.8 0.0 41.7 44.6 31.4 10.5 50.7 0.2 25.5 16.6 17.3 14.3 9.4 7.3 2.1 6.6 26.5 1.3 7.9 19.7 2.8 11.4 13.4 17.9 6.6 13.5 0.0 7.7 1.7 12.9 8.6 13.7 16.5 35.7 10.8 5.8 10.4 0.0 0.0 3.7 10.2 10.0 25.8 3.2 6.2 13.2 14.2 0.0 12.7 7.4 3.1 0.0 0.0 15.9 4.8 7.5 35.3 27.5 0.3 7.0 5.3 2.0 6.6 10.0 13.9 3.0 19.8 11.6 25.4 9.0 27.0 11.0 4.2 16.4 TLR1 "CD281, KIAA0012, rsc786" ENSG00000174125 "Toll like receptor 1" Q15399 4 38790677-38856817 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3;lymphoid tissue: 26.9" "Cell type enhanced" "Detected in many" "B-cells: 15.4;Hofbauer cells: 14.9;Kupffer cells: 34.9;Macrophages: 32.7;Microglial cells: 29.0;monocytes: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 128.5" "Group enriched" "Detected in all" 6 "granulocytes: 128.5;monocytes: 42.7" "Cell line enhanced" "Detected in many" "Daudi: 11.3;HUVEC TERT2: 12.6;RPMI-8226: 14.4;U-698: 20.6;U-937: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (7.82e-2)" "unprognostic (3.35e-3)" "unprognostic (4.02e-2)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (3.88e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-2)" "unprognostic (1.76e-1)" "unprognostic (7.25e-3)" "unprognostic (4.08e-2)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (3.97e-2)" 8.8 4.1 1.9 26.9 2.1 34.3 7.3 2.3 1.8 4.6 2.8 4.9 6.5 6.0 2.1 3.3 6.0 9.6 2.3 1.8 2.4 4.4 8.8 10.8 16.2 4.9 3.2 10.2 5.1 1.6 1.0 10.0 5.2 3.5 6.8 1.4 9.0 3.7 0.5 1.8 6.2 9.8 3.9 24.9 6.4 1.3 4.1 8.1 1.6 3.4 19.7 8.0 1.1 6.7 0.2 2.0 0.1 0.0 0.3 1.5 0.0 0.0 0.5 0.1 1.1 0.2 5.4 11.3 1.1 0.0 5.3 0.3 0.1 1.4 0.3 1.3 0.5 1.4 0.5 0.0 0.1 2.1 0.6 0.4 0.3 0.5 0.0 0.4 12.6 0.2 1.6 3.3 1.7 0.0 0.5 4.6 0.0 0.0 0.0 7.7 0.1 14.4 1.3 0.0 0.0 1.5 0.0 0.1 0.5 0.1 0.1 2.7 3.3 1.1 0.5 0.1 0.7 1.2 0.2 20.6 2.8 7.7 0.3 0.1 22.0 8.3 3.0 30.8 2.3 6.5 3.2 2.5 13.8 5.6 3.1 1.8 128.5 5.6 42.7 4.5 1.3 9.0 1.9 2.1 2.3 1.8 1.8 2.4 4.9 3.2 5.2 3.9 4.1 6.7 1.0 0.0 1.5 1.0 15.4 0.3 0.6 3.0 1.8 0.3 2.9 1.1 0.2 0.0 4.4 1.8 0.0 0.1 8.6 0.6 1.9 5.5 0.0 6.1 0.7 2.6 0.0 0.8 0.7 4.4 0.2 3.1 2.0 4.7 3.8 0.1 0.4 2.5 14.9 0.0 1.6 0.4 2.0 34.9 14.6 0.2 0.0 32.7 0.0 29.0 19.2 1.9 6.2 3.5 2.2 2.0 0.3 2.6 2.1 1.1 0.6 1.1 7.8 0.2 0.0 3.9 0.5 0.1 0.3 0.8 0.6 0.1 6.1 2.6 1.4 1.4 TLR10 CD290 ENSG00000174123 "Toll like receptor 10" Q9BXR5 4 38772238-38782990 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 47.9" "Cell type enhanced" "Detected in some" "B-cells: 57.2;dendritic cells: 9.4;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory B-cell: 39.0;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 5 "B-cells: 39.0" "Group enriched" "Detected in some" 53 "Daudi: 68.6;REH: 22.9;U-698: 24.7" "Low region specificity" "Detected in many" HPA066755 Approved Centrosome,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol Centrosome "HPA066755: " "unprognostic (5.41e-5)" "unprognostic (2.41e-4)" "unprognostic (1.91e-3)" "unprognostic (8.22e-4)" "unprognostic (6.48e-2)" "unprognostic (9.98e-4)" "unprognostic (9.31e-2)" "unprognostic (8.76e-3)" "unprognostic (4.08e-3)" "unprognostic (7.26e-2)" "unprognostic (8.76e-2)" "unprognostic (6.90e-2)" "unprognostic (2.98e-3)" "unprognostic (3.90e-1)" "unprognostic (1.81e-2)" "unprognostic (3.14e-3)" "unprognostic (1.88e-2)" 0.9 0.3 1.0 15.8 0.9 1.4 0.8 1.0 1.2 0.2 0.5 1.4 1.2 0.4 0.4 0.5 0.5 1.3 0.1 0.9 1.2 0.2 0.4 0.8 42.3 1.9 1.5 0.0 0.1 0.1 0.2 0.2 2.0 1.0 1.9 0.1 1.4 0.4 0.2 0.5 10.0 0.3 2.0 24.3 2.9 0.1 1.4 5.1 0.4 0.1 47.9 2.7 0.1 2.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 68.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 22.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.4 0.0 0.1 0.0 24.7 0.0 0.1 0.0 0.3 0.4 0.9 0.0 2.8 0.0 39.0 0.0 0.0 6.4 24.0 0.1 0.1 1.3 0.1 3.6 7.2 0.0 1.8 1.0 0.9 1.0 1.2 0.9 1.2 1.9 1.5 2.0 2.0 1.4 2.2 0.2 0.0 1.1 0.0 57.2 0.4 0.2 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.1 0.6 1.2 2.7 0.3 0.0 0.0 0.9 0.0 0.2 1.3 0.0 0.4 0.3 0.8 0.0 0.3 0.2 0.0 1.9 0.8 0.0 0.0 4.5 0.0 16.9 1.0 0.2 0.0 4.5 0.1 0.0 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 TLR6 CD286 ENSG00000174130 "Toll like receptor 6" Q9Y2C9 4 38823715-38856817 "CD markers, Enzymes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.8" "Cell type enhanced" "Detected in some" "B-cells: 13.6;Hofbauer cells: 7.2;Kupffer cells: 12.2;Langerhans cells: 6.6;Macrophages: 11.6;Microglial cells: 20.6;monocytes: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 13.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.3;GAMG: 13.5;RPMI-8226: 10.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062733 Approved "Endoplasmic reticulum" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "HPA062733: AB_2684853" "unprognostic (9.82e-2)" "unprognostic (4.76e-2)" "unprognostic (3.30e-2)" "unprognostic (3.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.87e-2)" "unprognostic (1.83e-1)" "unprognostic (4.45e-2)" "unprognostic (9.26e-2)" "unprognostic (1.30e-1)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (7.62e-7)" "unprognostic (4.89e-2)" "unprognostic (1.02e-2)" "unprognostic (7.78e-2)" "unprognostic (2.12e-2)" 1.6 1.6 1.2 10.3 1.1 6.6 1.4 1.4 1.1 1.0 1.4 1.6 1.6 1.0 0.5 1.4 1.2 3.5 0.6 1.1 1.9 0.5 2.0 2.6 10.8 2.6 1.9 1.3 0.4 0.5 0.4 2.6 3.0 0.9 2.1 0.1 2.0 0.5 0.3 0.7 4.4 2.0 2.7 9.7 2.2 0.3 2.8 2.0 0.6 1.3 13.8 3.2 0.8 4.4 1.6 6.1 0.2 0.1 0.3 6.8 0.0 1.7 7.3 0.7 2.4 0.0 13.3 7.5 2.8 0.3 13.5 0.7 0.1 1.3 1.1 0.0 0.5 3.4 7.3 0.2 0.4 3.9 5.5 2.9 1.4 2.9 1.6 0.2 1.5 1.1 3.9 2.3 3.3 0.0 0.0 6.7 0.2 0.0 1.0 3.7 3.2 10.8 0.4 0.1 0.0 0.1 0.2 0.0 1.0 0.3 0.3 2.0 2.1 2.3 7.8 0.9 2.7 0.1 0.0 6.1 5.3 4.4 1.7 0.0 2.6 0.8 0.2 2.5 0.0 1.7 0.1 0.1 1.8 1.0 0.2 0.1 13.4 0.3 1.3 1.2 0.3 0.7 1.2 1.1 1.4 1.1 1.1 1.9 2.6 1.9 3.0 2.7 2.8 4.4 0.6 0.0 0.0 0.3 13.6 0.6 1.2 0.3 0.0 0.6 1.2 0.8 1.2 0.0 0.2 0.0 0.0 0.0 2.2 0.2 0.0 0.5 0.0 0.5 0.7 1.1 0.0 0.4 0.2 0.2 0.2 0.9 0.0 1.2 2.5 0.3 0.4 0.2 7.2 0.0 0.9 0.1 0.0 12.2 6.6 0.0 0.6 11.6 0.0 20.6 14.0 0.2 1.0 0.5 0.3 0.3 0.1 0.7 3.7 0.9 0.2 0.0 1.3 0.8 0.0 0.9 0.5 0.2 0.0 0.2 0.9 0.3 1.7 1.4 0.1 0.8 TLR7 ENSG00000196664 "Toll like receptor 7" Q9NYK1 X 12867072-12890361 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 6.4" "Cell type enhanced" "Detected in some" "B-cells: 10.1;dendritic cells: 24.1;Hofbauer cells: 24.6;Macrophages: 20.2;Microglial cells: 14.0;monocytes: 11.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 20.7" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Daudi: 16.3;U-266/70: 16.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059613 Supported NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA059613: AB_2684083" "unprognostic (1.22e-1)" "unprognostic (1.09e-2)" "unprognostic (2.36e-3)" "unprognostic (9.29e-2)" "unprognostic (2.06e-1)" "unprognostic (1.06e-2)" "unprognostic (8.27e-2)" "unprognostic (6.20e-3)" "unprognostic (3.75e-1)" "unprognostic (6.91e-2)" "unprognostic (3.55e-1)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (4.17e-3)" "unprognostic (1.19e-3)" "unprognostic (1.53e-3)" "unprognostic (1.34e-1)" 1.1 1.6 1.3 4.3 1.2 0.6 4.1 1.6 1.3 1.3 1.0 1.9 1.8 0.9 0.5 0.6 0.8 2.9 0.7 1.1 1.5 0.6 0.6 4.6 4.3 3.5 2.5 0.7 0.3 0.9 0.2 6.4 3.5 0.8 2.3 0.1 1.4 1.0 0.1 0.1 1.8 2.0 3.4 3.8 1.7 0.5 2.7 3.8 0.4 0.3 5.6 2.5 0.1 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 16.3 0.0 3.1 0.0 0.3 0.0 0.4 10.0 4.5 0.0 11.6 0.0 8.7 0.0 0.0 4.9 7.2 0.0 0.0 0.5 0.1 9.7 20.7 0.0 3.3 1.3 1.2 1.6 1.3 1.1 1.5 3.5 2.5 3.5 3.4 2.7 6.1 0.2 0.0 3.9 0.0 10.1 1.3 1.3 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.6 0.0 2.1 0.3 24.1 0.0 0.0 0.0 0.0 0.3 0.2 1.3 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.5 1.3 0.0 0.7 0.2 24.6 0.0 0.1 0.0 0.0 6.2 8.1 0.7 0.6 20.2 1.8 14.0 11.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 5.7 0.9 0.0 0.0 2.2 0.7 0.0 4.5 0.5 0.0 0.1 0.1 1.0 0.3 2.5 0.1 0.0 1.6 TLR9 CD289 ENSG00000239732 "Toll like receptor 9" Q9NR96 3 52221080-52225645 "CD markers, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.1;lymphoid tissue: 6.0" "Group enriched" "Detected in some" 5 "B-cells: 3.3;Microglial cells: 1.0;Paneth cells: 1.1;Plasma cells: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "plasmacytoid DC: 166.9" "Lineage enriched" "Detected in many" 7 "dendritic cells: 166.9" "Group enriched" "Detected in some" 8 "Daudi: 53.5;RPMI-8226: 52.4;U-698: 27.6" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (6.03e-2)" "unprognostic (5.08e-2)" "unprognostic (3.58e-3)" "unprognostic (6.69e-7)" "unprognostic (1.16e-1)" "unprognostic (1.89e-2)" "unprognostic (2.69e-1)" "unprognostic (1.58e-1)" "unprognostic (7.02e-2)" "unprognostic (1.89e-1)" "unprognostic (4.40e-2)" "unprognostic (7.60e-2)" "unprognostic (2.65e-3)" "unprognostic (2.44e-2)" "unprognostic (3.70e-1)" "unprognostic (2.27e-1)" "unprognostic (7.91e-3)" 0.5 0.2 0.9 2.6 1.0 1.3 0.4 2.2 6.1 1.2 0.7 0.9 0.4 0.7 0.0 0.3 0.9 0.6 0.3 1.1 0.8 0.3 0.3 0.6 6.0 1.1 1.0 1.5 0.1 0.0 0.3 0.2 1.7 0.7 0.1 0.0 0.7 0.2 1.2 0.3 1.3 0.1 0.9 3.0 0.5 0.4 0.9 1.5 0.6 0.4 4.1 0.7 0.8 1.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.7 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 5.4 1.1 0.0 0.0 0.0 1.0 0.0 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.0 0.1 0.0 0.0 3.6 1.7 27.6 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.2 2.7 23.5 0.9 0.6 0.3 12.8 0.2 0.2 0.5 0.0 0.0 166.9 2.5 1.8 0.9 1.0 2.2 6.1 1.1 0.8 1.1 1.0 1.7 0.9 0.9 1.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TMED8 FAM15B ENSG00000100580 "Transmembrane p24 trafficking protein family member 8" Q6PL24 14 77335029-77377094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 62.7;Cone photoreceptor cells: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001205 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "HPA001205: AB_2204460" "unprognostic (1.07e-1)" "unprognostic (4.70e-2)" "unprognostic (4.85e-2)" "unprognostic (2.39e-1)" "unprognostic (1.13e-1)" "unprognostic (7.82e-2)" "unprognostic (1.68e-2)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (2.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.23e-3)" "unprognostic (1.12e-1)" "unprognostic (5.88e-2)" "unprognostic (2.77e-1)" 5.5 8.3 8.2 8.6 9.6 7.7 5.7 4.7 8.4 5.9 4.1 4.4 3.3 6.7 5.1 3.6 5.4 4.1 3.4 7.5 16.6 10.4 3.4 4.6 17.5 7.9 10.5 7.3 5.6 11.1 9.2 4.4 11.2 5.9 4.8 24.2 4.4 5.9 2.3 4.9 5.5 5.6 6.9 8.0 6.2 6.8 12.8 9.8 10.9 2.4 19.5 4.7 3.5 5.9 14.7 12.0 13.9 12.4 8.5 7.6 11.8 9.2 6.0 9.4 10.1 7.5 8.1 58.7 7.5 7.5 7.7 10.0 10.4 10.5 14.6 18.6 6.3 19.6 9.5 7.9 5.9 9.6 51.8 8.0 7.4 12.3 11.0 9.5 13.5 47.7 10.1 15.4 9.5 14.4 15.2 14.2 6.9 10.7 12.0 12.2 12.7 4.7 9.9 9.0 17.2 10.4 15.9 9.4 11.8 10.6 15.2 15.9 9.7 9.7 6.2 17.5 10.7 12.3 25.2 28.9 11.1 17.7 14.3 2.3 0.7 2.2 0.3 0.9 0.4 2.1 0.5 0.4 0.6 2.1 0.3 0.5 1.0 0.5 0.8 1.0 0.7 0.5 8.2 9.6 4.7 8.4 7.5 16.6 7.9 10.5 11.2 6.9 12.8 5.9 6.6 3.2 7.8 62.7 33.9 6.6 4.9 7.7 2.8 33.4 12.5 8.3 16.8 8.6 5.3 22.0 108.4 10.5 7.9 6.5 5.9 6.4 4.8 9.8 15.5 10.4 44.3 15.4 44.7 4.7 10.0 8.4 7.1 9.0 0.0 9.1 8.9 9.8 7.8 28.6 40.7 6.3 10.2 24.8 7.7 6.9 14.6 19.8 5.4 21.5 16.8 14.9 6.2 39.7 24.2 6.8 3.3 14.3 19.9 7.5 3.2 22.2 20.9 39.3 13.1 7.1 8.4 6.8 15.7 8.2 8.9 4.1 10.3 19.8 6.7 4.3 TMEM154 FLJ32028 ENSG00000170006 "Transmembrane protein 154" Q6P9G4 4 152618628-152680012 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.3;skin 1: 58.5" "Cell type enhanced" "Detected in many" "B-cells: 108.6;Basal keratinocytes: 74.2;Glandular and luminal cells: 75.0;granulocytes: 101.2;monocytes: 82.1;Squamous epithelial cells: 119.2;Suprabasal keratinocytes: 194.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 6.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 403.7;eosinophil: 305.7;neutrophil: 477.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 477.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 63.0;HMC-1: 71.1;Karpas-707: 55.6;U-266/70: 69.7;U-937: 56.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019184, HPA055411" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Nuclear membrane" Nucleoplasm "HPA019184: AB_2670088, HPA055411: " "unprognostic (1.09e-1)" "unprognostic (3.56e-1)" "unprognostic (5.17e-2)" "unprognostic (3.09e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-1)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (2.64e-1)" "unprognostic (1.65e-1)" "unprognostic (5.00e-3)" "unprognostic (7.67e-2)" "unprognostic (2.23e-3)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" 3.1 0.5 0.3 17.2 0.7 18.6 4.3 0.6 1.7 5.7 0.5 3.1 2.6 1.6 0.7 58.3 1.4 5.1 0.8 0.4 0.7 0.6 5.9 5.1 14.3 0.8 0.6 0.2 1.0 0.3 0.8 3.8 1.1 2.0 2.6 0.2 6.9 2.3 0.4 58.5 3.6 1.8 0.7 12.4 5.9 0.2 1.0 6.2 3.6 1.9 26.4 11.6 7.9 1.0 32.1 0.1 0.3 0.1 0.5 8.7 14.1 8.0 29.1 8.5 16.2 0.4 4.2 32.5 3.3 7.6 9.3 22.8 0.0 63.0 15.5 0.1 0.1 1.8 0.5 0.0 8.9 25.7 71.1 8.3 29.7 27.1 23.4 0.0 21.4 19.7 0.1 55.6 0.7 2.3 10.1 8.0 1.6 0.1 7.8 1.2 0.1 0.2 47.5 19.4 0.1 1.2 2.2 6.2 1.0 8.4 1.0 17.8 8.6 1.2 5.1 0.7 11.1 69.7 26.0 18.1 11.7 56.6 6.6 403.7 37.8 305.7 4.9 38.2 9.2 51.6 10.9 7.9 19.6 45.1 10.7 7.4 477.5 0.8 43.7 2.5 22.5 17.2 0.3 0.7 0.6 1.7 0.4 0.7 0.8 0.6 1.1 0.7 1.0 1.0 6.5 12.8 19.3 0.0 108.6 74.2 9.0 23.6 20.5 0.1 8.8 4.8 1.7 0.0 20.9 22.0 2.1 25.0 9.8 0.9 0.0 6.4 0.1 31.9 13.4 6.7 1.2 6.6 0.5 3.7 14.5 5.2 8.2 75.0 101.2 0.1 0.7 4.6 4.5 3.3 0.3 0.7 14.2 9.8 15.7 0.2 0.6 28.2 5.4 15.9 82.1 0.1 5.2 3.5 0.1 21.5 7.1 0.0 45.7 5.4 0.0 0.3 60.5 0.7 0.0 3.0 3.6 0.1 0.5 119.2 194.4 25.9 28.6 0.5 2.6 27.2 TMEM156 FLJ23235 ENSG00000121895 "Transmembrane protein 156" Q8N614 4 38966744-39032922 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 26.8" "Cell type enhanced" "Detected in many" "B-cells: 99.8;Microglial cells: 68.4;NK-cells: 28.8;Plasma cells: 123.1;T-cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 74.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 39.6;GAMG: 29.6;HBEC3-KT: 84.8;hTERT-HME1: 64.0;NB-4: 35.2;PC-3: 37.3;U-698: 45.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "prognostic favorable (4.09e-4)" "unprognostic (7.36e-3)" "unprognostic (3.31e-3)" "unprognostic (4.17e-3)" "unprognostic (1.82e-1)" "unprognostic (1.01e-3)" "unprognostic (4.10e-2)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (1.43e-1)" "unprognostic (9.45e-3)" "unprognostic (5.17e-2)" "unprognostic (8.73e-4)" "unprognostic (3.89e-1)" "unprognostic (1.74e-2)" "unprognostic (3.92e-4)" "unprognostic (9.06e-2)" 0.4 1.7 1.7 9.0 1.6 1.9 1.1 2.0 1.8 0.5 1.7 1.7 1.8 0.5 0.2 0.5 0.5 1.9 0.3 1.9 1.9 0.5 2.8 0.9 23.6 2.7 2.2 0.4 0.3 0.2 0.1 0.1 2.8 0.6 1.9 0.5 0.9 0.5 0.5 0.4 5.1 0.4 2.3 11.1 2.6 0.2 1.9 5.1 0.4 0.0 26.8 3.0 0.2 3.4 2.4 23.9 0.2 0.2 0.0 0.6 0.2 0.1 6.4 0.0 0.0 0.2 0.3 39.6 0.3 0.0 29.6 0.2 0.2 84.8 0.3 0.4 0.0 2.1 7.7 0.5 13.3 16.8 0.3 0.1 4.2 1.7 64.0 4.9 7.3 6.5 5.8 0.2 2.8 0.2 3.1 35.2 0.1 0.9 37.3 0.8 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.1 1.2 17.9 2.9 0.5 0.2 0.7 0.2 0.1 45.3 5.0 15.2 0.1 16.8 0.8 48.6 12.2 0.3 14.3 74.8 20.7 12.2 8.4 59.9 8.0 10.4 1.8 12.5 0.3 12.4 15.4 8.3 1.7 1.6 2.0 1.8 1.9 1.9 2.7 2.2 2.8 2.3 1.9 3.4 0.6 0.0 1.8 0.7 99.8 0.5 0.8 0.5 0.0 0.6 2.3 2.4 0.3 17.2 1.9 0.0 0.0 0.1 22.1 0.0 0.0 0.5 1.3 0.3 1.1 3.3 0.0 4.2 0.6 0.0 1.2 0.8 1.5 0.2 0.0 0.0 2.9 0.4 1.6 1.7 0.7 0.2 2.0 22.8 2.7 2.8 0.0 8.4 10.6 68.4 2.7 0.1 28.8 0.5 2.5 1.1 0.0 0.0 123.1 0.8 0.0 0.4 1.5 0.5 0.0 1.4 0.6 0.8 0.1 0.0 0.6 0.3 30.2 0.1 0.3 0.8 TMEM19 FLJ10936 ENSG00000139291 "Transmembrane protein 19" Q96HH6 12 71686082-71705047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016830 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "HPA016830: AB_1858107" "unprognostic (8.22e-2)" "unprognostic (3.47e-2)" "unprognostic (6.76e-2)" "unprognostic (1.44e-1)" "unprognostic (4.45e-1)" "unprognostic (3.43e-2)" "unprognostic (7.60e-2)" "unprognostic (5.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-2)" "unprognostic (4.27e-2)" "unprognostic (1.49e-2)" "unprognostic (4.42e-1)" "unprognostic (5.32e-3)" "unprognostic (1.00e-1)" 11.4 10.9 8.0 16.9 9.5 8.1 20.6 9.9 8.8 13.3 12.4 27.2 34.4 8.1 9.8 31.1 12.2 11.0 15.7 8.3 10.5 38.3 24.7 16.2 18.7 10.5 9.8 4.2 16.2 15.2 6.9 9.4 10.4 7.5 20.3 13.8 12.5 13.0 25.2 21.7 30.1 14.8 10.8 18.2 14.7 7.1 9.1 20.1 13.6 21.9 30.9 19.4 16.6 12.3 35.9 45.5 30.8 18.2 47.7 22.0 18.6 28.4 33.8 32.7 28.5 22.2 32.3 66.2 38.0 54.4 27.2 45.9 27.1 30.6 43.8 48.5 32.4 38.4 29.4 25.1 13.1 40.9 37.1 20.0 33.7 41.8 13.6 26.1 35.6 58.4 23.0 37.9 49.9 17.4 39.7 11.9 17.3 22.3 30.1 29.8 45.4 37.8 30.0 82.1 33.7 26.8 49.6 25.5 12.9 23.5 38.2 12.1 35.1 45.8 22.2 20.1 25.9 73.9 101.4 47.7 19.4 11.7 50.0 26.0 27.1 10.4 33.2 34.3 25.7 102.3 26.1 28.2 47.6 118.6 25.2 30.3 2.3 28.8 31.3 134.5 29.8 33.7 8.0 9.5 9.9 8.8 8.3 10.5 10.5 9.8 10.4 10.8 9.1 12.3 12.8 22.4 16.3 9.8 44.7 19.1 18.8 32.7 14.8 12.9 11.7 5.8 22.4 12.8 20.1 25.8 12.5 13.6 37.9 21.9 11.7 15.8 16.4 7.4 6.0 14.9 19.9 9.9 7.2 21.6 25.1 11.8 6.6 7.5 15.8 7.4 16.4 31.1 25.9 15.2 9.2 14.5 34.6 32.1 33.7 75.3 7.5 24.2 23.2 5.6 21.4 11.0 22.6 9.5 12.2 22.1 20.2 13.5 54.8 6.9 51.2 46.1 30.6 8.8 6.6 7.5 9.0 4.4 8.4 43.8 46.5 4.8 12.4 7.7 27.4 16.6 TMEM243 "C7orf23, MGC4175, MM-TRAG" ENSG00000135185 "Transmembrane protein 243" Q9BU79 7 87196160-87220587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 192.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 150.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014918 Uncertain NA Yes "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA014918: AB_2067447" "unprognostic (5.14e-3)" "unprognostic (7.27e-2)" "unprognostic (1.36e-1)" "unprognostic (3.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (3.39e-2)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (6.84e-4)" "unprognostic (4.58e-2)" "unprognostic (2.69e-1)" "unprognostic (6.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (2.32e-2)" "prognostic favorable (9.13e-4)" 28.6 16.4 16.3 31.0 17.0 28.5 26.7 16.8 20.1 31.9 20.2 19.3 24.8 21.9 38.7 18.2 27.9 22.6 16.2 16.2 16.5 36.6 8.6 52.6 68.1 16.9 16.8 35.4 35.1 20.3 22.4 32.6 16.7 24.9 17.3 5.8 32.0 24.1 5.2 21.0 38.8 16.0 17.8 44.2 27.4 10.9 17.3 27.4 69.8 8.1 80.3 23.0 27.1 18.1 35.7 21.1 20.7 25.8 48.5 54.0 49.7 28.5 42.9 20.9 38.2 29.7 42.1 76.1 61.1 28.7 37.9 33.4 19.8 28.6 27.7 32.5 52.7 1.2 38.5 63.2 38.0 27.7 5.7 36.0 28.3 16.1 32.2 40.0 31.6 39.3 3.6 39.8 28.7 58.7 34.9 4.5 23.4 4.1 28.9 68.0 62.0 105.1 61.0 27.3 22.7 20.4 21.2 43.4 33.0 35.7 16.2 4.9 17.0 35.2 30.9 90.2 25.1 56.1 52.2 150.0 32.2 25.3 21.0 53.3 34.8 23.9 45.3 38.3 65.6 181.9 81.6 57.4 61.5 170.8 135.6 95.5 15.7 67.7 25.6 129.4 79.7 38.8 16.3 17.0 16.8 20.1 16.2 16.5 16.9 16.8 16.7 17.8 17.3 18.1 45.0 25.6 109.4 6.5 192.9 42.7 44.0 55.7 31.9 6.1 40.0 42.4 1.0 34.3 32.9 22.0 39.6 111.8 102.2 8.1 52.8 26.2 139.6 41.6 21.3 41.6 7.3 13.9 14.8 42.5 43.8 44.7 21.9 18.9 2.5 25.6 32.9 3.4 48.9 11.8 13.9 23.5 14.2 66.5 62.4 23.0 83.0 45.6 51.6 22.5 43.7 8.8 50.4 6.6 6.1 24.3 24.5 59.0 144.9 51.4 34.6 70.0 34.6 12.2 46.0 24.6 19.8 16.8 43.2 23.6 38.1 33.5 85.1 29.3 39.7 43.7 TNF "DIF, TNF-alpha, TNFA, TNFSF2" ENSG00000232810 "Tumor necrosis factor" P01375 6 31575565-31578336 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in many" "B-cells: 90.7;dendritic cells: 60.8;Langerhans cells: 72.7;Macrophages: 108.3;T-cells: 100.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 68.0" "Group enriched" "Detected in all" 5 "granulocytes: 20.8;monocytes: 68.0;T-cells: 36.6" "Group enriched" "Detected in some" 8 "HDLM-2: 103.7;NB-4: 214.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB078469 Supported "Secreted to blood" NA NA 10100 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "CAB078469: AB_908070" "unprognostic (1.93e-1)" "unprognostic (1.07e-2)" "unprognostic (3.85e-2)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-2)" "unprognostic (1.67e-1)" "unprognostic (3.46e-1)" "unprognostic (1.19e-2)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-2)" "unprognostic (1.82e-1)" "unprognostic (9.85e-3)" "unprognostic (1.09e-1)" "unprognostic (2.04e-1)" 1.4 0.5 0.0 3.3 0.0 12.7 0.5 0.0 0.1 0.1 0.0 0.9 0.0 1.5 0.0 0.7 0.3 0.6 2.6 0.1 0.0 1.2 0.6 3.6 1.6 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 1.5 2.4 0.2 0.1 6.5 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.8 0.0 0.0 0.0 0.0 103.7 0.0 19.4 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 214.4 0.0 0.0 0.0 9.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 10.1 0.0 23.2 39.5 36.6 7.2 17.2 13.9 7.6 7.0 5.0 5.2 20.8 2.0 68.0 4.3 13.6 14.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 3.0 0.0 90.7 8.4 1.2 12.1 4.6 0.2 17.4 20.4 2.0 2.8 4.0 0.0 2.1 0.9 60.8 0.5 0.0 7.4 0.1 15.5 5.9 10.7 0.0 0.0 0.0 3.3 1.7 2.0 1.5 30.5 12.6 0.0 1.8 0.1 36.5 0.0 0.0 0.4 10.2 14.1 72.7 0.0 0.3 108.3 5.4 1.9 3.4 0.1 2.1 0.0 0.1 14.3 0.0 0.0 10.4 1.7 0.0 0.1 3.0 0.2 0.0 0.6 4.0 0.0 0.0 1.3 4.1 1.1 100.0 0.0 0.4 0.3 TNFRSF13B "CD267, IGAD2, TACI" ENSG00000240505 "TNF receptor superfamily member 13B" O14836 17 16929816-16972118 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 18.9;lymphoid tissue: 33.0;skeletal muscle: 62.9" "Group enriched" "Detected in some" 4 "B-cells: 117.3;Plasma cells: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 41 "memory B-cell: 130.9;naive B-cell: 51.8" "Lineage enriched" "Detected in many" 59 "B-cells: 130.9" "Group enriched" "Detected in some" 9 "Karpas-707: 167.2;RPMI-8226: 106.7;U-266/70: 72.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030453 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "HPA030453: AB_10601700" "unprognostic (3.94e-5)" "unprognostic (1.11e-3)" "unprognostic (4.88e-2)" "unprognostic (4.30e-3)" "unprognostic (1.23e-4)" "unprognostic (2.16e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-2)" "unprognostic (1.61e-4)" "unprognostic (2.22e-1)" "unprognostic (9.78e-2)" "unprognostic (1.59e-5)" "unprognostic (1.20e-1)" "unprognostic (4.49e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" 0.4 0.1 0.3 8.9 0.4 1.1 0.7 0.0 0.5 0.3 0.0 3.4 4.1 0.1 0.0 1.3 0.4 0.5 5.3 0.1 0.3 0.3 0.3 0.8 17.3 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.9 0.4 2.5 0.3 2.1 0.3 62.9 0.0 18.9 0.1 0.2 33.0 5.2 0.1 0.4 2.0 0.5 0.0 21.6 2.6 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.2 106.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.6 0.0 13.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 130.9 0.0 0.0 0.0 51.8 0.0 0.1 0.5 0.0 0.0 0.0 2.2 2.7 0.3 0.4 0.0 0.5 0.1 0.3 0.4 0.3 0.9 0.2 0.4 1.2 0.0 0.0 0.0 0.0 117.3 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.1 0.0 0.0 0.4 1.1 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.5 32.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 143.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.6 0.0 6.2 0.0 0.0 0.0 TNFRSF13C "BAFFR, CD268" ENSG00000159958 "TNF receptor superfamily member 13C" Q96RJ3 22 41922032-41926806 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 33.8;lymphoid tissue: 58.1" "Cell type enriched" "Detected in some" 10 "B-cells: 194.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 36 "memory B-cell: 22.5;naive B-cell: 29.1" "Lineage enriched" "Detected in single" 40 "B-cells: 29.1" "Group enriched" "Detected in some" 6 "REH: 21.0;U-698: 10.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA003246, CAB008380" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "CAB008380: AB_590602, HPA003246: AB_1078264" "unprognostic (3.43e-4)" "prognostic favorable (4.44e-7)" "unprognostic (6.52e-2)" "unprognostic (9.10e-2)" "unprognostic (7.64e-3)" "unprognostic (4.83e-3)" "unprognostic (2.89e-2)" "unprognostic (3.78e-3)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (2.51e-2)" "unprognostic (1.66e-1)" "unprognostic (4.79e-8)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" "unprognostic (1.77e-1)" "unprognostic (9.44e-2)" 0.8 0.8 2.1 17.7 1.3 6.0 0.5 1.6 1.9 0.2 0.6 2.1 1.2 0.3 0.3 1.5 0.4 1.0 0.4 1.9 2.0 0.8 0.3 1.0 39.0 3.6 2.1 0.1 0.1 0.1 0.2 0.3 2.2 0.5 1.1 0.4 1.7 0.1 2.3 3.3 33.8 0.1 2.7 58.1 2.5 0.7 2.1 3.4 1.1 0.5 54.6 1.8 0.5 2.0 0.3 0.2 1.1 2.3 0.0 0.0 0.4 0.2 0.1 0.2 0.8 0.9 0.5 1.9 0.4 0.2 0.2 0.4 0.7 0.0 0.3 0.4 2.3 0.2 0.4 0.2 0.1 1.7 0.4 0.1 0.0 0.4 0.1 0.1 0.0 0.7 0.4 1.9 0.2 0.7 1.6 1.8 0.7 0.1 0.1 21.0 2.4 1.6 0.0 0.2 1.3 0.3 0.1 0.4 0.3 0.2 0.4 2.2 0.2 0.5 2.5 0.9 0.3 2.0 1.1 10.9 0.1 1.8 0.5 0.7 0.1 0.2 0.2 0.2 0.3 22.5 0.3 0.2 0.1 29.1 0.4 0.4 0.3 0.3 0.3 0.4 0.2 1.1 2.1 1.3 1.6 1.9 1.9 2.0 3.6 2.1 2.2 2.7 2.1 2.0 0.1 0.0 1.1 0.0 194.5 0.1 0.4 0.0 1.2 1.0 1.6 1.3 1.4 0.0 0.0 0.0 0.0 0.2 2.6 0.3 0.0 0.0 0.1 2.6 0.5 0.3 1.2 0.4 0.0 0.0 0.2 0.7 0.5 4.3 0.0 1.5 0.0 0.2 0.1 8.4 0.1 0.1 0.0 0.6 0.0 0.0 0.0 1.3 0.0 6.5 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 18.0 0.3 0.1 0.2 0.0 0.4 0.0 0.5 0.4 1.5 1.4 0.3 0.0 0.1 3.4 0.2 0.4 0.2 TRAF5 RNF84 ENSG00000082512 "TNF receptor associated factor 5" O00463 1 211326615-211374946 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 75.9;Early spermatids: 55.0;Late spermatids: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 36.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008052, CAB010277" Enhanced Supported Centrosome,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Cytosol Centrosome "CAB010277: AB_2287961, HPA008052: AB_1858230" "unprognostic (6.44e-2)" "unprognostic (1.05e-1)" "unprognostic (8.15e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.39e-2)" "unprognostic (6.44e-3)" "unprognostic (7.94e-3)" "unprognostic (1.39e-1)" "unprognostic (1.75e-1)" "unprognostic (5.92e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (2.94e-10)" "unprognostic (3.72e-1)" "unprognostic (1.34e-1)" "unprognostic (1.71e-2)" "prognostic favorable (7.29e-5)" 8.6 3.3 3.6 17.0 4.6 4.1 6.0 1.5 3.2 10.8 26.3 14.0 5.0 17.3 7.4 5.6 17.8 8.1 3.5 3.6 2.2 5.0 1.8 5.7 29.7 2.7 2.7 6.2 21.3 1.6 2.9 5.4 2.8 9.0 9.5 0.7 7.5 10.8 1.5 2.8 17.4 20.0 2.2 16.7 9.3 6.9 3.1 13.5 3.0 2.6 27.2 13.5 6.5 2.4 6.2 4.5 7.9 7.1 6.8 4.9 2.8 8.6 10.3 12.2 10.8 2.2 11.9 18.8 4.8 13.6 6.2 1.2 15.1 1.4 6.1 36.3 5.4 0.9 7.1 0.0 9.9 3.0 13.3 5.8 2.7 6.6 2.0 18.4 8.6 16.3 7.6 8.7 3.4 4.8 8.3 3.4 9.5 9.7 3.8 12.6 11.0 17.6 9.3 4.3 14.0 14.6 6.4 0.3 18.3 29.2 4.4 0.3 5.4 7.9 6.1 2.7 9.8 2.4 3.8 20.0 2.1 0.0 3.0 13.8 0.3 0.4 9.2 0.3 17.3 22.2 11.6 12.5 1.5 19.6 10.2 10.2 0.7 21.3 0.5 1.1 17.7 7.4 3.6 4.6 1.5 3.2 3.6 2.2 2.7 2.7 2.8 2.2 3.1 2.4 15.2 12.8 7.2 3.3 75.9 3.7 4.0 2.7 9.6 2.5 13.9 13.7 2.5 0.0 6.8 11.0 0.0 9.5 31.0 3.6 0.0 0.9 55.0 5.3 23.6 9.0 14.8 4.6 13.4 9.8 2.2 16.9 16.8 8.1 15.2 5.3 6.1 0.3 10.0 0.0 14.1 11.4 4.1 4.8 12.6 47.9 14.3 17.3 8.8 20.6 16.3 1.0 32.0 7.5 2.8 7.1 11.4 27.4 11.3 3.4 1.8 0.8 8.6 0.7 13.1 7.3 29.1 3.8 2.7 4.4 4.0 1.4 41.6 5.0 14.3 2.6 TRIM22 "GPSTAF50, RNF94, STAF50" ENSG00000132274 "Tripartite motif containing 22" Q8IYM9 11 5689697-5737089 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 135.9;dendritic cells: 113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 174.6;BJ hTERT+ SV40 Large T+ RasG12V: 209.9;HSkMC: 190.6;TIME: 153.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003307, HPA003575" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA003307: AB_1080381, HPA003575: AB_1080378" "unprognostic (1.47e-2)" "unprognostic (5.27e-3)" "unprognostic (4.00e-2)" "unprognostic (4.21e-3)" "unprognostic (2.21e-1)" "unprognostic (1.21e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (1.86e-3)" "unprognostic (2.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-2)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" "unprognostic (1.15e-1)" "unprognostic (9.16e-2)" 54.0 21.3 13.1 101.3 18.8 90.3 50.7 16.3 23.7 42.7 25.5 36.0 25.2 50.6 70.2 37.1 49.3 78.6 22.6 14.7 16.5 21.2 72.5 83.4 139.0 17.9 16.7 60.3 17.2 8.0 12.6 21.5 16.7 43.3 53.4 11.0 65.4 52.6 13.4 18.1 53.4 52.1 17.7 143.1 39.5 15.4 12.8 101.2 21.7 40.6 120.7 61.6 22.6 29.3 2.8 1.2 13.9 2.4 88.6 174.6 5.0 53.3 93.9 89.8 209.9 1.7 8.6 111.9 13.0 80.2 20.6 10.5 34.0 56.4 10.7 2.0 0.0 6.4 5.6 1.4 107.8 18.2 11.4 190.6 54.3 18.7 9.6 124.5 128.7 1.0 2.3 4.7 111.6 1.5 54.1 16.9 40.3 0.5 4.9 62.6 3.4 2.3 51.1 14.9 1.4 2.7 4.5 4.5 2.1 56.8 4.5 17.9 153.6 56.4 29.8 2.5 2.4 4.9 4.4 11.2 67.7 28.9 7.2 108.7 118.5 79.6 109.0 143.3 145.9 149.4 118.4 117.2 138.7 158.2 106.5 102.7 103.1 61.3 181.1 177.0 197.9 181.9 13.1 18.8 16.3 23.7 14.7 16.5 17.9 16.7 16.7 17.7 12.8 29.3 54.4 67.3 57.7 2.0 135.9 12.6 17.0 42.5 56.3 0.5 17.7 14.0 6.0 7.2 60.5 29.5 0.0 1.5 113.9 4.7 5.9 11.2 0.3 16.1 27.0 40.5 4.2 16.8 4.9 8.0 4.7 36.2 20.9 23.8 17.7 5.4 33.5 4.3 18.7 1.7 0.3 9.0 30.5 87.1 46.6 2.0 36.1 67.8 5.4 52.5 59.0 6.4 83.4 1.0 0.5 5.4 6.3 30.1 18.8 9.9 4.4 3.3 52.5 1.0 13.1 35.1 24.4 0.6 0.3 14.1 8.7 2.3 89.3 13.0 5.0 18.8 TRIM38 "RNF15, RORET" ENSG00000112343 "Tripartite motif containing 38" O00635 6 25962802-25991231 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031685 Approved Approved "Plasma membrane,Cell Junctions,Centrosome" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" Centrosome "Plasma membrane, Cell Junctions" "HPA031685: AB_10603218" "unprognostic (6.62e-2)" "unprognostic (1.65e-3)" "unprognostic (3.34e-1)" "unprognostic (2.72e-2)" "unprognostic (1.25e-1)" "unprognostic (6.51e-2)" "unprognostic (7.79e-2)" "unprognostic (3.27e-2)" "unprognostic (2.78e-2)" "prognostic favorable (8.95e-5)" "unprognostic (2.81e-2)" "unprognostic (6.28e-2)" "unprognostic (2.73e-1)" "unprognostic (3.36e-1)" "unprognostic (4.49e-2)" "prognostic favorable (8.20e-5)" "prognostic favorable (4.94e-9)" 7.1 6.0 1.8 10.8 1.8 13.0 6.1 1.6 2.4 7.3 3.4 5.8 6.6 7.3 9.6 7.8 7.4 6.6 3.7 1.7 1.9 9.9 5.6 9.3 13.6 3.0 2.1 4.6 3.2 2.9 2.0 6.3 2.7 7.0 7.3 0.4 6.1 6.2 7.6 5.2 8.9 6.1 2.4 14.3 5.8 2.1 2.7 7.7 5.5 3.0 14.6 7.0 7.0 2.7 4.8 2.6 0.4 5.6 13.0 17.3 4.6 5.9 11.7 11.2 18.5 2.0 5.0 10.5 9.4 7.3 10.8 7.3 3.6 5.8 6.6 10.7 2.3 4.8 4.6 2.0 17.2 5.7 9.4 17.4 4.2 6.9 2.5 9.2 9.8 5.0 3.2 5.7 13.5 2.3 5.5 6.4 1.8 0.0 3.5 8.3 5.4 11.2 13.3 9.3 0.1 0.1 4.4 9.1 16.2 0.6 1.3 7.3 10.1 2.0 3.4 3.5 4.0 6.5 5.1 11.7 5.4 6.9 12.6 12.1 10.2 4.7 6.9 12.5 6.6 13.1 5.8 6.2 9.8 15.1 5.4 6.0 11.4 6.5 11.7 9.0 7.9 7.1 1.8 1.8 1.6 2.4 1.7 1.9 3.0 2.1 2.7 2.4 2.7 2.7 37.6 25.6 47.1 0.3 120.2 14.9 56.9 16.1 24.5 0.6 20.1 12.8 6.0 18.6 32.4 46.0 0.0 23.5 88.5 48.3 17.6 28.5 1.1 48.4 28.1 39.9 18.1 10.3 0.1 14.9 23.5 25.5 24.5 69.4 35.5 52.4 35.0 17.5 32.6 0.0 0.1 33.3 16.2 94.0 32.7 2.8 19.9 81.3 10.6 34.7 113.2 0.2 107.1 0.0 0.2 20.4 47.4 18.8 34.3 39.7 48.3 69.5 22.7 1.1 6.6 23.1 28.2 0.3 0.5 42.7 9.2 21.2 53.1 23.0 25.6 94.7 TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: AB_10803995, HPA041380: AB_10793873" "unprognostic (2.10e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.54e-2)" "unprognostic (1.08e-3)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (7.62e-2)" "unprognostic (1.91e-2)" "unprognostic (8.74e-3)" "prognostic unfavorable (9.87e-7)" "unprognostic (1.19e-3)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" 22.0 19.8 16.5 16.2 15.3 21.1 21.0 14.7 22.1 24.3 14.8 20.0 11.8 22.9 6.3 22.3 23.6 8.9 17.3 15.5 14.7 18.0 22.1 17.3 23.2 16.0 14.8 28.7 25.4 10.0 17.2 11.3 16.8 23.0 10.9 6.5 17.0 11.4 28.8 23.4 21.7 12.5 14.2 30.6 18.9 16.8 16.2 11.6 19.2 10.5 15.9 22.3 22.2 17.6 38.6 25.3 26.9 46.0 26.7 34.1 38.7 42.1 20.9 45.3 39.1 27.4 30.8 47.7 53.6 22.9 23.7 34.8 45.2 37.3 20.9 31.3 62.8 38.0 68.7 46.5 48.7 77.2 43.1 48.4 48.4 47.3 44.1 28.9 33.8 35.2 83.7 14.9 28.6 42.6 31.7 83.3 64.0 24.2 57.5 52.5 34.6 65.8 28.3 38.2 63.5 28.9 26.2 53.7 44.8 19.4 21.0 42.8 38.2 65.1 25.5 39.8 75.1 25.6 53.4 44.1 30.3 80.7 34.7 1.8 18.9 0.6 8.9 15.0 8.6 12.4 9.6 8.6 18.2 12.9 11.1 8.5 3.7 5.6 9.9 10.6 6.9 10.7 16.5 15.3 14.7 22.1 15.5 14.7 16.0 14.8 16.8 14.2 16.2 17.6 15.5 12.8 13.1 8.5 47.5 24.0 27.0 16.8 22.8 8.9 16.6 20.2 8.3 11.5 9.6 12.9 2.1 21.7 19.6 16.6 5.9 17.3 22.4 7.9 11.7 17.6 7.2 13.0 12.0 14.9 22.6 14.3 17.9 9.8 29.8 19.7 6.1 10.8 47.7 8.4 9.1 14.1 4.1 80.0 51.0 47.9 14.0 57.4 17.8 10.3 64.8 6.1 12.3 2.5 7.5 12.8 6.8 12.8 24.2 29.0 7.8 14.2 9.2 12.6 13.1 17.5 16.1 21.1 20.0 20.7 20.6 15.5 24.4 14.6 22.5 20.3 USF1 "bHLHb11, MLTFI, UEF" ENSG00000158773 "Upstream transcription factor 1" P22415 1 161039251-161045977 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001480, HPA036233, HPA036535" Supported Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "CAB001480: AB_2213986, HPA036233: AB_2675012, HPA036535: AB_2675178" "unprognostic (3.66e-2)" "unprognostic (2.79e-2)" "unprognostic (9.12e-3)" "unprognostic (2.17e-1)" "unprognostic (9.40e-2)" "prognostic favorable (8.70e-4)" "unprognostic (1.59e-3)" "unprognostic (2.94e-2)" "unprognostic (3.57e-1)" "unprognostic (1.03e-3)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "prognostic unfavorable (6.01e-12)" "unprognostic (1.24e-3)" "unprognostic (3.29e-1)" "unprognostic (4.08e-1)" "prognostic favorable (1.95e-5)" 15.3 18.2 26.3 18.9 26.2 17.5 13.9 26.2 27.2 14.8 25.7 18.4 18.5 14.3 14.2 13.8 16.8 14.6 18.4 26.5 26.6 15.7 21.0 18.4 27.8 26.0 25.5 16.7 11.4 20.5 11.4 18.1 26.4 15.1 18.3 17.0 14.0 18.2 32.7 15.3 19.6 18.1 26.0 30.5 14.9 7.6 28.2 36.0 12.9 29.4 32.7 20.7 13.7 26.9 17.2 25.5 29.9 35.0 39.4 22.3 39.9 14.0 30.3 42.9 33.3 17.9 21.2 22.1 29.0 23.5 18.6 21.0 35.6 22.3 24.0 20.6 21.2 19.1 20.9 18.9 23.0 26.7 25.4 18.3 22.0 31.1 25.1 27.3 40.7 36.8 31.7 23.1 27.2 20.1 41.5 29.2 61.8 37.0 32.9 35.6 23.3 26.9 21.0 26.8 16.9 32.3 25.5 32.8 18.1 42.9 27.5 85.5 24.0 21.5 13.5 13.2 23.1 19.5 26.6 34.3 18.3 25.9 16.7 2.5 2.6 1.4 1.9 2.1 1.1 1.5 1.1 1.3 2.6 1.7 1.2 1.2 4.1 0.9 2.1 2.7 1.3 1.3 26.3 26.2 26.2 27.2 26.5 26.6 26.0 25.5 26.4 26.0 28.2 26.9 13.1 6.4 6.9 3.6 18.0 2.3 0.6 3.1 9.1 3.3 2.7 3.9 1.0 0.0 3.2 3.7 2.1 2.2 14.5 7.1 1.9 2.1 0.4 5.5 8.1 6.0 3.0 5.0 6.3 1.3 4.4 4.6 14.8 5.6 11.4 4.0 1.1 0.4 3.1 5.0 5.4 3.4 6.1 2.1 3.5 0.2 0.3 12.4 5.4 4.7 4.7 1.6 4.1 4.0 5.8 2.3 7.1 0.0 20.0 1.6 7.3 3.1 7.9 3.5 6.6 3.3 4.9 0.5 0.4 8.5 1.8 3.4 9.3 7.7 4.9 1.9 UVRAG VPS38 ENSG00000198382 "UV radiation resistance associated" Q9P2Y5 11 75815210-76144232 "Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 144.6;Microglial cells: 178.9;Oligodendrocytes: 361.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016932 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "HPA016932: AB_1858707" "unprognostic (3.92e-2)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (4.22e-3)" "unprognostic (2.29e-1)" "unprognostic (1.02e-1)" "unprognostic (1.15e-2)" "unprognostic (2.89e-1)" "unprognostic (2.96e-1)" "unprognostic (3.01e-1)" "unprognostic (7.89e-2)" "unprognostic (2.18e-2)" "unprognostic (6.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (6.94e-2)" "unprognostic (3.03e-1)" 32.1 12.8 11.4 17.9 16.9 33.9 20.7 12.1 15.4 13.7 35.9 14.5 10.6 13.3 14.3 10.1 13.3 15.3 10.7 11.4 12.8 11.6 15.3 15.4 26.5 15.0 15.9 12.4 8.2 21.3 7.3 18.2 16.9 10.5 12.4 19.2 8.0 11.4 14.5 11.8 10.6 14.9 16.0 21.4 12.7 7.9 13.9 25.2 12.9 14.7 25.4 13.1 8.9 25.2 10.3 14.4 11.2 9.7 27.2 20.2 16.3 15.0 27.5 17.4 13.8 19.7 18.9 49.5 30.5 20.5 30.7 10.8 19.5 17.5 19.9 27.2 7.8 18.3 12.2 16.8 24.2 30.6 19.1 17.4 14.6 23.8 42.6 13.1 51.0 22.0 19.6 29.7 16.5 24.1 20.9 19.6 11.1 32.1 15.7 17.3 28.5 40.9 14.8 35.0 15.3 10.8 16.6 16.7 13.2 17.1 20.9 27.4 45.3 16.8 12.7 62.4 10.3 18.4 23.3 51.0 7.6 16.0 21.3 5.8 9.9 8.4 7.0 8.8 6.4 23.4 6.1 6.9 16.8 26.6 8.2 6.6 13.9 8.1 11.4 24.0 6.3 4.7 11.4 16.9 12.1 15.4 11.4 12.8 15.0 15.9 16.9 16.0 13.9 25.2 97.3 12.8 21.3 53.8 97.0 9.2 9.4 9.8 26.7 52.2 17.5 19.4 16.1 10.0 11.3 7.3 68.8 37.6 41.6 9.5 7.9 11.5 6.2 13.6 28.1 36.5 5.4 24.6 144.6 8.7 10.3 24.7 34.1 18.5 10.8 16.0 20.0 9.2 17.3 53.8 124.6 10.0 8.2 22.0 50.8 2.6 21.5 46.3 8.8 178.9 45.8 19.0 34.0 89.0 361.8 10.5 11.4 16.1 40.4 12.1 10.8 11.0 6.5 53.1 13.1 27.2 28.6 13.5 19.1 19.4 12.6 32.8 28.1 25.1 10.1 9.1 VAV1 VAV ENSG00000141968 "Vav guanine nucleotide exchange factor 1" P15498 19 6772708-6857366 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.1;lymphoid tissue: 46.4" "Cell type enhanced" "Detected in many" "B-cells: 30.7;dendritic cells: 31.3;granulocytes: 34.9;Hofbauer cells: 50.6;Kupffer cells: 29.4;Macrophages: 33.9;Microglial cells: 30.9;T-cells: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 100.7;Karpas-707: 114.7;MOLT-4: 115.8;REH: 76.1;THP-1: 88.9;U-266/84: 89.5;U-937: 95.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001864, HPA005925" Enhanced Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA001864: AB_1858722, HPA005925: " "unprognostic (2.93e-1)" "unprognostic (1.96e-1)" "unprognostic (1.80e-1)" "unprognostic (1.01e-1)" "unprognostic (6.82e-2)" "unprognostic (1.13e-2)" "unprognostic (5.62e-1)" "unprognostic (1.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-2)" "unprognostic (3.56e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (9.55e-2)" "unprognostic (1.78e-1)" "unprognostic (6.57e-2)" "unprognostic (3.28e-1)" 6.6 3.8 3.3 36.3 3.3 54.1 2.7 3.6 4.6 2.6 4.5 6.5 5.8 1.8 1.4 3.7 2.4 6.3 1.9 3.3 4.4 2.1 5.0 11.5 46.4 6.2 4.9 1.1 1.3 4.2 1.6 8.7 5.6 2.8 7.1 0.2 6.1 2.3 1.0 1.7 14.1 5.3 5.0 44.9 5.5 1.8 5.7 45.7 2.0 2.1 39.1 13.0 1.7 7.6 1.6 2.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 12.7 51.0 16.5 0.0 0.0 0.2 0.0 0.0 0.0 22.0 1.8 61.8 0.0 0.0 0.0 60.7 100.7 0.0 0.0 0.0 0.0 0.0 0.0 63.9 2.3 114.7 0.0 9.6 115.8 36.6 0.0 0.0 0.0 76.1 0.0 41.0 2.2 0.0 0.0 0.0 0.0 18.3 0.1 0.0 8.0 88.9 0.2 0.0 1.6 0.1 0.1 69.9 89.5 57.9 0.1 95.3 0.0 1.6 18.3 20.0 22.0 30.3 15.7 14.3 16.1 19.3 16.6 13.6 17.2 15.6 40.6 19.2 39.8 14.4 14.5 18.2 3.3 3.3 3.6 4.6 3.3 4.4 6.2 4.9 5.6 5.0 5.7 7.6 0.5 3.2 3.0 0.0 30.7 1.3 0.8 3.7 0.0 0.5 0.4 0.4 1.1 0.0 6.9 0.0 0.0 0.8 31.3 1.5 0.0 4.2 5.4 5.3 0.3 1.5 1.2 9.9 1.9 0.4 0.7 1.2 1.1 1.1 34.9 0.0 1.8 0.3 50.6 0.0 1.5 1.0 8.2 29.4 19.6 2.2 0.0 33.9 1.8 30.9 18.8 0.0 22.6 0.5 1.2 9.9 6.1 0.0 21.6 0.3 0.0 0.2 11.9 0.0 0.0 0.3 1.2 1.7 1.4 0.3 0.9 1.4 26.5 0.3 2.4 0.6 VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141778-10153667 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 146.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031631, HPA031632, HPA068954" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: " "prognostic unfavorable (9.02e-5)" "unprognostic (1.10e-1)" "unprognostic (4.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.55e-1)" "unprognostic (3.03e-2)" "unprognostic (4.36e-2)" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (2.51e-1)" "prognostic favorable (7.84e-4)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (1.28e-3)" 14.0 13.7 11.5 21.1 11.0 27.9 14.7 13.6 12.1 11.8 6.7 14.8 15.7 14.1 9.8 12.3 13.4 11.5 7.9 11.8 14.9 12.6 14.1 11.8 29.6 9.4 9.4 12.6 12.7 11.7 9.0 14.1 9.3 14.0 15.7 8.9 14.5 10.2 11.4 14.2 17.2 12.8 9.6 22.5 16.0 13.4 16.6 23.4 15.8 7.7 29.7 12.5 10.9 12.5 19.5 18.2 39.9 24.6 36.0 27.7 146.5 16.8 24.0 21.1 24.5 21.5 23.7 67.9 22.2 23.0 29.9 16.4 37.2 23.6 25.7 33.0 33.7 52.7 30.5 30.6 34.3 47.3 41.3 28.1 26.3 28.0 35.1 28.4 24.6 42.5 48.3 50.3 21.1 35.0 45.5 40.9 26.7 21.1 23.4 57.3 34.6 34.6 25.5 48.7 15.0 49.4 35.0 18.7 21.0 23.9 37.0 59.1 21.3 20.8 27.7 19.6 26.8 35.7 78.1 105.6 23.2 55.3 19.4 4.6 3.2 2.3 2.6 2.2 1.9 2.5 1.8 2.2 2.0 3.3 1.7 1.8 5.6 3.0 2.0 2.3 1.7 1.2 11.5 11.0 13.6 12.1 11.8 14.9 9.4 9.4 9.3 9.6 16.6 12.5 12.4 12.8 12.5 9.1 38.7 14.7 17.8 14.3 24.5 14.7 10.7 6.1 6.1 20.0 9.6 16.5 18.8 16.8 21.9 10.7 7.9 11.8 9.6 13.1 26.1 14.8 14.4 30.5 15.9 5.1 18.7 12.8 20.9 19.9 5.1 18.4 18.9 14.3 14.9 18.5 14.2 11.3 16.2 27.1 45.8 7.3 14.0 32.3 12.4 7.5 31.9 9.1 28.8 12.1 14.9 10.7 11.7 11.3 33.3 23.8 12.3 9.5 9.7 15.3 6.6 17.4 11.9 15.4 24.0 26.7 20.5 17.2 23.5 21.4 10.2 25.9 VPREB3 8HS20 ENSG00000128218 "V-set pre-B cell surrogate light chain 3" Q9UKI3 22 23752743-23754425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;intestine: 72.5;lymphoid tissue: 118.5" "Cell type enriched" "Detected in some" 12 "B-cells: 287.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 709 "memory B-cell: 753.3;naive B-cell: 803.7" "Lineage enriched" "Detected in many" 732 "B-cells: 803.7" "Group enriched" "Detected in some" 46 "Daudi: 263.3;REH: 309.9;U-698: 85.2" "Low region specificity" "Detected in single" HPA003041 Supported "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA003041: AB_1080577" "unprognostic (2.06e-3)" "unprognostic (4.75e-3)" "unprognostic (2.35e-1)" "unprognostic (2.39e-2)" "unprognostic (1.21e-2)" "unprognostic (2.75e-2)" "unprognostic (4.79e-2)" "unprognostic (6.63e-3)" "unprognostic (9.15e-2)" "unprognostic (1.38e-2)" "unprognostic (4.93e-2)" "unprognostic (4.84e-2)" "unprognostic (8.44e-2)" "unprognostic (4.19e-2)" "unprognostic (1.18e-1)" "unprognostic (2.87e-1)" "unprognostic (4.12e-1)" 1.7 21.1 2.0 41.3 2.0 25.8 0.4 2.6 3.8 0.3 2.6 3.9 1.7 1.1 51.5 1.2 0.3 2.7 1.1 1.7 2.0 1.6 1.9 0.8 112.4 2.1 2.1 0.1 0.5 0.6 2.5 0.2 2.1 1.6 3.7 2.2 2.5 0.3 1.6 0.6 72.5 0.3 1.9 60.3 6.1 0.6 2.9 7.9 1.7 0.5 118.5 6.2 0.3 1.8 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.6 263.3 0.3 0.2 0.0 0.1 0.5 0.2 0.1 0.6 2.8 0.1 0.0 0.2 0.2 0.3 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.4 0.4 1.1 0.0 1.3 0.5 1.0 0.3 0.3 1.1 309.9 0.5 4.7 0.1 0.1 0.7 1.0 0.3 0.7 3.5 0.2 0.6 0.4 1.2 0.0 0.5 0.9 0.0 1.3 0.3 85.2 0.0 0.5 0.3 0.9 0.7 0.6 0.4 0.3 0.4 753.3 0.4 0.5 0.7 803.7 0.5 0.5 1.0 0.4 0.7 0.6 1.0 17.5 2.0 2.0 2.6 3.8 1.7 2.0 2.1 2.1 2.1 1.9 2.9 1.8 0.1 0.0 0.5 0.3 287.8 0.4 0.8 0.6 0.6 4.5 0.3 0.5 0.9 1.5 0.8 0.0 2.1 0.0 5.4 1.1 1.9 0.1 0.3 0.1 0.8 0.1 5.4 2.7 0.2 0.0 0.0 1.5 1.5 0.3 0.0 0.7 1.1 1.0 0.3 0.0 0.2 0.6 2.0 0.3 0.8 0.2 0.0 1.2 5.4 0.0 0.7 0.8 2.1 0.5 0.1 0.1 0.3 0.0 22.6 0.2 1.5 2.4 0.0 2.1 0.0 0.5 0.4 0.1 0.2 0.4 0.1 0.0 3.5 0.1 0.7 0.3 ZBED5 Buster1 ENSG00000236287 "Zinc finger BED-type containing 5" Q49AG3 11 10812074-10858796 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048472, HPA050994" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center" "HPA048472: AB_2680408, HPA050994: AB_2681300" "unprognostic (7.74e-2)" "unprognostic (1.36e-1)" "unprognostic (2.37e-1)" "unprognostic (4.72e-2)" "unprognostic (3.40e-1)" "unprognostic (9.05e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (5.69e-2)" "unprognostic (4.61e-2)" "unprognostic (2.23e-2)" "unprognostic (2.25e-2)" "unprognostic (3.27e-2)" "unprognostic (8.77e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic favorable (3.87e-4)" 26.4 22.0 16.9 36.6 22.5 34.1 32.7 35.3 20.0 39.4 23.3 33.1 25.6 45.6 35.7 26.4 38.5 25.8 32.5 16.8 18.0 33.1 15.7 31.5 57.1 20.1 18.5 45.1 28.8 35.0 30.5 27.9 21.1 36.3 29.9 50.8 29.6 21.9 33.3 51.4 36.5 28.9 19.5 42.9 28.5 21.3 18.7 49.7 40.1 29.1 45.4 30.7 31.7 32.7 46.8 36.7 63.1 41.2 33.8 52.0 32.7 37.4 38.2 24.8 24.5 27.0 99.6 50.7 27.5 28.0 34.5 56.8 39.8 39.3 33.1 49.8 35.5 13.4 89.3 15.6 27.5 42.3 17.1 36.0 55.3 18.8 41.0 44.3 31.0 25.3 35.0 56.0 36.0 23.6 41.9 46.2 34.1 33.3 47.8 62.8 34.3 27.4 29.2 64.6 30.9 54.4 38.4 49.1 30.6 35.3 46.8 23.1 31.1 53.2 38.4 35.9 26.6 27.9 36.8 39.8 46.0 29.5 41.2 1.1 8.7 8.0 11.0 9.6 14.3 20.6 13.1 14.1 12.2 21.2 17.0 17.2 7.3 17.8 11.6 15.8 12.3 8.5 16.9 22.5 35.3 20.0 16.8 18.0 20.1 18.5 21.1 19.5 18.7 32.7 17.1 57.7 33.0 32.0 44.6 34.7 46.1 25.0 34.7 32.8 15.9 11.8 38.8 20.0 39.4 22.0 29.2 17.1 13.6 12.3 23.5 22.2 6.9 13.9 29.4 22.7 27.6 8.8 18.1 16.2 8.5 27.3 15.3 14.0 8.8 25.8 20.7 6.2 12.1 28.6 22.3 15.6 26.4 15.7 19.8 7.9 27.4 19.3 16.0 16.9 18.1 21.6 14.4 25.6 40.9 18.3 13.1 27.4 26.6 25.3 12.5 14.5 42.7 35.8 19.7 41.2 25.2 43.4 22.2 25.9 35.7 12.4 22.6 18.7 16.7 28.5 ZCCHC7 "AIR1, FLJ22611" ENSG00000147905 "Zinc finger CCHC-type containing 7" Q8N3Z6 9 37120574-37358149 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 225.6;Inhibitory neurons: 229.6;Oligodendrocyte precursor cells: 196.1;Oligodendrocytes: 250.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 124.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020600, HPA021088, HPA029522" Uncertain Enhanced Nucleoli,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoli, Cytosol" "HPA020600: AB_1858985, HPA021088: AB_1858986, HPA029522: AB_10601029" "unprognostic (1.19e-3)" "unprognostic (1.21e-1)" "unprognostic (2.60e-2)" "unprognostic (2.36e-1)" "unprognostic (7.21e-3)" "unprognostic (2.78e-1)" "unprognostic (4.27e-3)" "unprognostic (3.18e-2)" "unprognostic (8.00e-3)" "unprognostic (1.29e-2)" "unprognostic (7.87e-2)" "unprognostic (1.83e-1)" "unprognostic (4.58e-2)" "unprognostic (8.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.04e-2)" "unprognostic (5.49e-2)" 8.3 7.4 5.8 12.7 5.5 13.7 13.2 18.7 8.8 9.3 5.1 8.2 7.9 11.6 11.3 7.5 9.6 7.9 6.4 5.3 5.4 7.4 8.1 6.5 23.2 5.6 6.2 16.6 11.2 7.1 9.4 7.9 6.6 7.0 10.9 9.9 7.8 7.1 5.9 8.2 8.2 9.5 4.4 10.6 7.7 12.1 7.4 12.9 12.3 6.0 24.8 9.5 7.5 9.2 17.2 9.4 17.5 18.4 17.4 27.0 15.5 17.4 21.3 14.0 19.2 11.8 8.6 54.8 8.1 14.0 15.9 7.2 16.6 17.1 19.9 26.3 8.8 19.1 19.3 10.7 27.3 32.5 17.5 18.6 26.3 14.2 56.7 26.0 16.0 24.4 53.3 21.8 12.7 8.2 24.9 18.2 18.3 20.3 17.3 124.7 11.0 16.2 17.6 7.1 17.5 12.9 12.6 15.3 17.1 16.9 10.2 21.4 12.7 9.9 11.8 14.1 10.3 5.0 13.2 76.4 14.9 20.8 18.7 8.4 7.6 20.6 12.9 9.0 12.8 32.6 14.9 15.0 7.2 48.9 18.6 17.3 15.3 18.4 17.2 13.2 13.4 9.3 5.8 5.5 18.7 8.8 5.3 5.4 5.6 6.2 6.6 4.4 7.4 9.2 27.7 35.3 18.5 126.3 110.3 28.3 29.5 28.2 32.5 15.5 21.7 23.7 10.7 15.7 21.7 5.5 10.4 15.3 32.8 7.7 27.4 16.3 52.2 17.6 37.6 18.7 19.1 38.5 225.6 15.8 25.4 31.0 30.1 24.2 23.5 18.0 16.4 11.6 15.2 11.8 229.6 22.5 40.7 17.9 22.8 20.8 27.1 20.3 16.0 121.8 19.8 18.2 28.8 196.1 250.0 12.8 13.6 19.5 44.7 34.9 17.7 22.5 19.1 24.9 6.6 33.9 25.4 60.1 44.8 29.3 32.7 18.6 42.2 32.4 20.3 26.0 ZNF107 "smap-7, ZFD25, ZNF588" ENSG00000196247 "Zinc finger protein 107" Q9UII5 7 64666083-64711582 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.2" "Cell type enhanced" "Detected in many" "B-cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 47.0;REH: 49.5;U-698: 51.2" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.25e-1)" "unprognostic (1.70e-1)" "unprognostic (3.50e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-1)" "unprognostic (9.11e-2)" "unprognostic (1.67e-2)" "unprognostic (2.51e-2)" "unprognostic (4.13e-3)" "unprognostic (1.62e-2)" "unprognostic (2.34e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (3.32e-1)" "unprognostic (1.66e-1)" "unprognostic (5.49e-2)" "unprognostic (7.15e-3)" 2.3 5.9 1.5 8.8 2.5 8.6 8.3 2.9 1.9 6.8 0.7 2.7 2.7 2.9 2.3 2.7 2.7 2.5 1.3 1.8 2.0 2.1 1.6 2.3 16.2 2.8 2.1 4.4 1.6 2.1 1.8 3.1 2.7 3.3 3.5 3.3 4.8 2.6 0.8 7.5 7.7 2.1 2.1 8.5 3.7 2.8 2.1 13.4 5.0 1.8 14.2 3.2 3.6 3.7 6.8 4.1 11.3 19.8 2.6 2.7 8.3 5.0 3.3 7.4 9.8 6.3 6.3 39.6 8.9 3.3 10.0 5.2 12.6 5.1 11.1 9.7 8.5 7.8 6.6 3.5 1.1 14.9 13.3 4.6 3.5 6.4 3.7 3.7 3.7 36.1 13.8 20.2 6.6 5.7 47.0 15.9 22.0 4.2 4.5 49.5 9.1 8.8 3.7 13.3 12.6 10.1 7.8 8.0 5.1 15.6 12.6 9.7 3.2 12.3 5.0 4.7 7.4 9.4 9.1 51.2 2.8 10.0 8.1 12.0 0.7 1.5 3.4 1.7 3.6 9.0 4.6 4.8 1.1 10.1 6.0 5.8 13.7 2.6 1.3 2.8 4.3 1.8 1.5 2.5 2.9 1.9 1.8 2.0 2.8 2.1 2.7 2.1 2.1 3.7 7.9 12.8 4.2 10.4 45.2 2.2 3.2 3.2 8.6 6.2 13.9 5.8 3.8 5.7 5.4 7.3 2.1 2.7 9.0 1.3 1.9 2.6 8.2 5.1 5.7 6.9 6.6 5.9 6.2 3.1 2.4 6.7 5.1 5.9 0.0 15.0 4.2 0.6 1.9 3.3 9.7 2.9 2.0 3.8 1.5 7.8 4.4 4.8 0.0 10.3 1.7 4.1 10.3 22.6 22.1 3.9 2.4 3.4 22.8 3.5 2.0 1.9 3.3 5.7 6.6 4.0 3.9 4.3 4.7 5.5 4.1 2.5 17.9 17.5 3.6 3.8 ZNF141 "D4S90, pHZ-44" ENSG00000131127 "Zinc finger protein 141" Q15928 4 337814-384868 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "unprognostic (6.88e-3)" "unprognostic (4.64e-2)" "unprognostic (2.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.47e-1)" "unprognostic (3.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.11e-1)" "unprognostic (5.02e-2)" "unprognostic (1.47e-3)" "unprognostic (2.71e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.76e-4)" 4.7 13.9 8.6 3.3 9.1 1.3 4.8 12.5 12.1 8.8 9.1 5.3 2.4 5.1 4.2 4.2 6.9 1.5 5.1 8.9 8.6 6.1 6.1 6.5 5.1 8.1 8.2 15.6 5.5 3.2 8.5 2.3 8.3 7.6 2.5 13.7 5.9 2.5 2.5 4.8 6.2 1.2 7.6 7.1 4.4 5.6 8.5 3.3 7.5 1.1 4.3 5.5 6.7 9.2 0.1 1.3 5.0 2.0 1.4 1.9 1.3 1.5 0.9 2.1 3.0 4.4 2.6 0.3 1.2 1.2 2.5 2.1 0.0 1.2 2.8 0.0 1.2 0.1 2.3 0.2 1.0 0.1 4.8 2.2 1.3 2.1 0.9 1.1 0.5 1.0 0.1 0.2 2.1 1.4 4.3 6.3 5.4 0.5 2.3 0.1 0.0 0.5 1.5 2.7 5.0 2.5 1.8 0.7 1.3 2.6 2.2 4.8 0.4 0.3 1.6 1.2 1.5 0.1 0.2 0.2 0.0 0.0 0.9 0.5 0.5 1.0 1.3 0.6 1.3 1.2 1.1 1.1 1.0 1.8 1.6 1.3 0.9 1.4 0.9 0.7 0.9 0.5 8.6 9.1 12.5 12.1 8.9 8.6 8.1 8.2 8.3 7.6 8.5 9.2 9.5 6.4 7.7 14.7 28.3 3.7 3.3 2.0 6.2 24.0 5.2 5.8 5.3 8.6 4.2 14.7 14.6 3.5 11.2 2.6 5.9 3.5 7.9 4.5 9.3 9.6 6.0 8.4 9.9 2.9 3.0 9.7 4.6 5.6 5.7 22.8 3.9 2.0 2.3 33.7 11.6 2.7 2.0 2.2 6.0 6.1 11.1 12.2 3.6 15.0 5.5 7.9 16.5 15.1 16.3 2.9 1.0 6.0 7.2 2.8 3.3 1.7 4.8 18.1 26.3 9.8 21.3 10.6 9.7 3.3 4.1 4.1 13.5 15.3 4.5 2.2 ZNF296 ZNF342 ENSG00000170684 "Zinc finger protein 296" Q8WUU4 19 45071500-45076587 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.2" "Cell type enhanced" "Detected in many" "B-cells: 53.3;Basal squamous epithelial cells: 94.4;Plasma cells: 48.2;Squamous epithelial cells: 107.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 24.0;SK-BR-3: 15.6;U-698: 28.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA046940, HPA049576" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Centrosome "HPA046940: AB_2679871, HPA049576: AB_2680821" "unprognostic (1.32e-1)" "unprognostic (5.37e-3)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.24e-4)" "unprognostic (3.83e-3)" "unprognostic (1.67e-2)" "unprognostic (9.70e-2)" "unprognostic (9.55e-2)" "unprognostic (3.20e-3)" "unprognostic (1.12e-1)" "unprognostic (2.67e-5)" "unprognostic (7.14e-3)" "unprognostic (1.52e-1)" "unprognostic (1.74e-1)" "unprognostic (1.39e-3)" 0.6 1.1 1.4 2.2 1.2 5.3 1.7 3.3 1.9 1.3 0.4 2.5 3.0 0.5 0.1 9.2 1.4 0.2 0.4 1.4 1.0 1.5 0.7 1.3 2.8 1.2 1.1 0.7 0.7 0.1 3.3 0.1 1.2 2.4 0.3 0.5 5.1 0.4 0.5 6.0 4.2 0.1 1.1 5.9 2.7 2.3 1.0 0.4 1.2 0.1 1.4 1.5 3.2 0.9 4.6 2.9 0.1 0.6 0.0 0.2 2.5 0.6 0.0 0.3 0.2 4.7 1.6 24.0 2.7 0.1 0.0 8.3 1.2 1.8 0.0 5.2 6.3 7.2 1.4 4.8 1.2 3.9 7.2 0.9 0.9 0.9 0.0 0.1 0.7 0.4 5.2 8.0 0.0 6.5 0.3 6.8 2.7 2.8 6.3 13.5 0.0 14.8 0.5 1.6 4.4 0.4 3.0 15.6 0.1 0.4 3.4 8.1 1.5 0.0 2.4 0.1 0.0 8.6 9.3 28.7 0.2 5.0 0.1 59.7 10.7 17.2 8.3 18.3 9.7 82.6 4.3 9.3 26.0 62.8 1.8 4.7 5.1 45.9 18.5 78.5 4.4 8.7 1.4 1.2 3.3 1.9 1.4 1.0 1.2 1.1 1.2 1.1 1.0 0.9 2.4 0.0 0.6 2.3 53.3 12.1 13.9 1.5 94.4 1.4 20.5 13.3 1.2 0.0 2.6 3.7 4.2 0.4 31.9 18.5 0.0 1.8 0.5 6.1 1.0 2.0 5.3 3.0 0.4 0.9 3.6 1.3 21.9 4.5 8.9 0.5 1.4 0.2 3.5 0.0 0.3 32.1 6.1 2.9 19.1 0.5 0.0 7.6 3.6 0.0 24.9 0.4 12.3 0.0 0.5 1.2 36.1 1.2 48.2 6.4 23.4 0.2 3.9 1.6 0.0 0.8 3.2 1.1 14.2 107.3 10.1 0.8 18.5 0.2 28.9 6.2 ZNF45 ZNF13 ENSG00000124459 "Zinc finger protein 45" Q02386 19 43912624-43935282 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038611, HPA075124" Uncertain Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA038611: AB_10669544, HPA075124: AB_2686735" "unprognostic (1.67e-2)" "unprognostic (4.84e-1)" "unprognostic (1.07e-2)" "unprognostic (1.84e-3)" "unprognostic (1.23e-1)" "unprognostic (9.31e-2)" "unprognostic (5.34e-2)" "unprognostic (1.04e-1)" "unprognostic (1.60e-3)" "unprognostic (1.91e-1)" "unprognostic (7.68e-3)" "unprognostic (5.17e-3)" "unprognostic (5.17e-3)" "unprognostic (1.67e-1)" "unprognostic (1.66e-1)" "unprognostic (4.43e-2)" "unprognostic (5.82e-2)" 4.8 5.5 3.0 5.1 3.7 6.3 7.1 6.3 3.4 6.7 3.7 5.2 5.6 7.1 5.5 4.6 6.5 5.1 4.6 3.1 4.9 5.8 5.8 5.9 7.3 3.7 3.4 9.0 4.0 9.7 5.0 5.3 3.2 6.7 6.1 8.5 4.9 5.8 6.5 5.9 5.3 6.0 3.2 7.3 5.0 3.6 3.8 10.7 7.4 5.8 7.1 5.1 3.9 4.5 9.2 12.1 16.9 15.1 8.0 7.0 5.9 11.7 12.7 12.0 18.2 5.9 3.7 13.3 7.0 7.3 9.2 5.2 12.9 8.5 15.0 11.2 13.7 19.7 10.6 5.3 7.4 19.5 12.8 7.1 8.4 8.8 7.7 11.9 9.7 4.5 6.3 5.2 13.0 4.2 11.6 4.9 19.8 8.6 5.1 9.4 16.8 4.8 7.3 20.1 11.6 19.0 16.4 6.6 5.8 10.8 6.9 12.7 10.1 13.3 19.4 5.6 10.8 21.1 37.1 14.5 5.6 7.5 15.7 3.4 3.7 5.7 5.6 3.4 8.4 5.8 5.4 6.0 4.9 4.1 7.4 5.0 1.1 6.3 4.7 3.2 6.1 4.2 3.0 3.7 6.3 3.4 3.1 4.9 3.7 3.4 3.2 3.2 3.8 4.5 2.9 3.2 1.7 7.5 4.2 1.5 0.8 2.2 3.4 1.8 3.1 2.0 3.3 1.5 3.6 0.0 6.2 2.0 5.1 2.4 0.0 2.3 0.2 2.4 1.9 2.4 2.4 3.4 5.0 1.5 1.1 2.3 3.6 2.6 0.0 3.2 1.8 2.1 2.9 3.3 4.9 3.2 2.0 2.8 1.6 0.6 1.8 2.5 1.8 10.3 2.4 1.6 1.0 8.0 9.0 1.2 0.7 4.9 1.5 1.7 2.6 1.9 4.1 2.4 19.7 2.4 1.9 1.1 2.1 3.9 1.6 1.2 3.7 2.4 2.1 1.5 ZNF586 FLJ20070 ENSG00000083828 "Zinc finger protein 586" Q9NXT0 19 57769655-57819939 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 18.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA030306, HPA060782" Approved Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Vesicles "HPA030306: AB_2673423, HPA060782: AB_2684362" "prognostic favorable (9.83e-5)" "unprognostic (1.60e-2)" "unprognostic (2.93e-1)" "unprognostic (1.72e-3)" "unprognostic (2.52e-2)" "unprognostic (2.60e-1)" "unprognostic (1.10e-2)" "unprognostic (1.02e-3)" "unprognostic (3.22e-3)" "unprognostic (2.06e-2)" "unprognostic (1.88e-1)" "unprognostic (2.99e-2)" "unprognostic (1.72e-2)" "unprognostic (6.01e-2)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "prognostic favorable (5.36e-4)" 5.2 4.3 3.6 6.3 4.0 25.4 6.9 18.9 4.1 6.1 5.9 5.6 5.9 5.9 5.0 6.6 5.9 4.9 6.0 3.6 4.6 5.3 4.8 5.8 11.8 2.4 2.2 9.0 6.5 4.2 4.8 6.9 2.0 8.4 5.9 9.3 8.9 4.1 9.7 8.3 6.5 5.8 0.3 10.4 7.2 5.0 3.0 13.4 6.2 7.2 9.8 6.5 7.2 4.3 7.2 6.0 8.6 9.6 4.1 3.7 14.4 5.0 5.3 7.0 3.8 2.8 7.2 16.1 0.4 4.6 6.6 4.7 1.6 7.2 13.1 2.4 30.9 12.2 15.1 1.6 7.5 12.0 10.4 6.4 7.5 5.2 7.6 7.9 8.5 15.6 8.0 0.7 8.3 1.7 12.3 8.2 12.8 4.8 17.3 11.9 3.2 20.2 8.3 17.8 11.9 5.9 2.3 7.4 5.8 7.4 7.1 7.6 4.6 9.2 5.1 0.3 8.8 15.4 23.0 17.1 5.0 1.3 6.6 8.0 9.6 31.5 8.4 8.0 8.2 7.0 10.8 8.9 8.9 9.7 13.3 12.2 29.5 10.1 5.4 6.6 15.1 7.3 3.6 4.0 18.9 4.1 3.6 4.6 2.4 2.2 2.0 0.3 3.0 4.3 3.9 0.0 1.5 3.6 13.6 12.1 7.9 6.6 9.6 3.6 4.9 4.2 4.8 0.0 3.3 3.7 0.0 7.1 8.5 2.1 9.8 3.4 0.9 4.3 2.8 4.5 3.0 4.4 4.0 2.0 6.9 3.4 2.6 5.7 3.8 8.6 5.0 3.5 5.5 6.7 4.7 4.0 8.2 8.2 6.8 1.1 0.9 5.6 3.6 1.9 7.1 3.1 6.2 3.0 3.4 2.1 1.7 2.6 9.2 3.6 4.4 5.9 2.2 5.2 6.6 2.6 3.8 10.4 8.7 7.0 11.4 10.0 9.2 4.5 4.0 8.5 ZNF595 FLJ31740 ENSG00000272602 "Zinc finger protein 595" Q8IYB9 4 53286-88208 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 60.5" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 106.0;K-562: 249.2;SH-SY5Y: 159.9" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" "unprognostic (6.33e-2)" "unprognostic (2.95e-1)" "unprognostic (6.98e-2)" "unprognostic (1.03e-2)" "unprognostic (2.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-1)" "unprognostic (6.63e-3)" "unprognostic (2.52e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" "unprognostic (2.31e-1)" "unprognostic (2.68e-1)" "unprognostic (6.46e-2)" 8.0 8.4 4.3 7.1 4.3 8.9 9.9 12.1 6.9 8.7 1.6 6.5 4.3 10.7 6.0 5.2 7.7 5.1 4.8 4.2 5.4 4.9 6.3 7.2 10.2 6.5 5.0 14.7 10.1 5.4 4.2 60.5 7.1 7.4 6.1 10.1 5.6 4.3 5.3 7.4 6.1 10.9 3.7 9.5 6.3 8.7 4.5 10.6 10.3 6.6 10.1 5.9 7.3 6.2 4.0 13.8 8.9 8.3 50.4 61.9 68.3 4.8 4.4 5.3 6.9 6.6 5.7 106.0 7.9 4.0 9.0 3.0 50.3 4.7 7.8 8.5 7.2 0.4 0.1 0.0 3.2 0.1 26.8 6.8 6.1 5.2 5.5 5.7 4.4 47.9 249.2 1.1 4.3 30.5 0.3 29.6 15.6 0.0 6.2 0.1 2.0 0.1 7.7 4.5 7.3 159.9 6.1 7.0 2.8 35.3 50.3 17.1 29.3 5.4 39.3 3.2 6.1 0.4 53.4 12.6 0.2 0.1 18.0 5.9 2.7 16.0 8.5 3.5 3.9 16.3 4.7 5.8 4.3 17.3 6.4 6.3 4.5 23.3 3.2 15.7 4.0 4.9 4.3 4.3 12.1 6.9 4.2 5.4 6.5 5.0 7.1 3.7 4.5 6.2 9.1 6.4 11.7 10.7 11.3 4.6 10.1 4.3 6.8 8.7 5.0 6.5 5.6 8.6 12.5 3.7 2.1 10.5 10.8 2.9 15.6 8.1 5.4 2.0 7.6 9.9 0.0 1.7 21.9 4.4 9.8 8.2 3.1 2.6 7.6 18.8 10.8 3.8 4.0 3.3 24.0 3.4 2.0 1.8 4.2 6.1 11.1 2.7 5.4 22.5 1.6 11.8 33.0 24.1 34.9 3.1 2.9 9.1 13.2 6.4 3.0 4.6 2.3 6.8 0.0 9.7 5.7 16.0 16.8 2.6 4.5 8.5 5.0 9.3 3.4 6.6 ZNF627 FLJ90365 ENSG00000198551 "Zinc finger protein 627" Q7L945 19 11559374-11619161 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA049770, HPA073463" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 57: B-cells - Immune response" Nucleoplasm Nucleoli "HPA049770: AB_2680871, HPA073463: AB_2686606" "unprognostic (1.81e-1)" "unprognostic (9.89e-2)" "unprognostic (1.64e-2)" "unprognostic (3.14e-2)" "unprognostic (7.89e-3)" "prognostic favorable (8.12e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (1.83e-3)" "unprognostic (3.17e-2)" "unprognostic (2.03e-1)" "unprognostic (1.67e-2)" "prognostic favorable (6.93e-7)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-1)" "unprognostic (6.39e-3)" 5.6 4.1 5.7 4.3 5.9 7.6 11.1 7.4 6.8 8.3 6.0 5.9 5.7 10.6 8.7 4.6 12.2 5.0 5.2 5.6 5.9 9.6 7.1 6.1 6.8 6.1 6.0 13.1 7.5 8.9 5.8 6.3 5.9 8.0 6.8 8.3 5.9 6.5 4.0 5.5 5.0 6.2 6.2 6.6 6.0 8.0 6.3 9.3 13.1 5.6 5.6 6.4 5.6 7.9 6.0 5.2 15.0 18.8 6.7 6.9 8.5 8.4 10.0 9.5 9.5 3.9 4.0 4.6 8.4 6.6 4.8 5.1 6.0 8.2 10.5 8.3 2.8 12.8 2.8 7.6 12.5 6.9 6.9 8.4 11.6 6.2 14.3 14.5 10.6 10.9 11.9 6.0 12.5 12.3 11.3 6.9 11.3 4.0 10.4 12.6 11.3 6.3 10.8 9.2 20.8 15.5 11.5 6.1 12.6 12.7 11.1 19.6 9.2 10.0 4.8 6.2 5.9 8.6 9.0 4.8 4.6 11.3 8.4 14.2 4.5 7.4 4.6 4.9 5.3 9.0 5.6 5.8 7.2 5.8 7.4 6.7 2.4 7.3 4.8 2.7 3.2 4.2 5.7 5.9 7.4 6.8 5.6 5.9 6.1 6.0 5.9 6.2 6.3 7.9 2.9 12.8 5.9 6.2 11.2 1.3 3.4 4.0 6.2 4.5 6.2 5.8 15.0 7.2 3.1 9.2 4.2 5.2 5.4 3.7 17.6 5.4 7.9 7.0 4.9 4.3 5.3 8.0 4.5 2.6 4.3 4.3 10.2 3.7 1.3 6.1 6.1 6.1 3.2 6.7 4.8 3.2 10.2 4.4 4.4 4.0 5.3 3.1 0.0 3.7 3.2 4.9 3.1 6.6 7.3 4.1 3.1 5.3 6.7 4.9 3.5 7.3 11.6 5.8 0.0 3.1 4.7 15.5 4.4 3.6 2.7 4.7 4.8 3.1 4.3 3.3 ZNF860 ENSG00000197385 "Zinc finger protein 860" A6NHJ4 3 31981750-31991723 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.2" "Cell type enhanced" "Detected in some" "B-cells: 14.0;Extravillous trophoblasts: 3.8;Respiratory ciliated cells: 4.3;Syncytiotrophoblasts: 4.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 7.0;naive B-cell: 5.2" "Lineage enriched" "Detected in single" 56 "B-cells: 7.0" "Cell line enriched" "Detected in many" 4 "BEWO: 44.8" HPA063386 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA063386: AB_2684999" "unprognostic (1.19e-1)" "unprognostic (2.46e-2)" "unprognostic (2.88e-1)" "unprognostic (1.64e-2)" "unprognostic (1.51e-1)" "unprognostic (8.01e-2)" "unprognostic (1.23e-2)" "unprognostic (1.94e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (1.51e-2)" "unprognostic (6.38e-2)" "unprognostic (1.30e-4)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (8.74e-2)" "unprognostic (3.75e-3)" 0.3 0.2 0.2 1.4 0.2 0.1 1.4 0.0 0.2 1.5 0.5 0.6 0.2 0.9 2.3 1.7 1.0 0.6 0.2 0.4 0.3 1.0 0.0 0.7 3.1 0.1 0.6 0.6 0.1 0.0 1.4 1.3 0.3 2.8 0.8 0.7 1.4 1.2 0.1 1.2 1.2 0.7 0.0 1.6 0.6 1.0 0.3 0.4 0.9 0.2 4.2 1.1 0.8 0.1 3.0 0.9 0.0 2.3 0.0 0.1 44.8 0.2 0.1 0.2 0.3 3.0 3.5 3.3 3.3 0.0 1.4 2.8 1.0 4.5 0.3 0.0 0.4 0.0 4.4 1.5 0.0 0.0 0.0 0.2 2.0 0.3 8.6 0.3 0.8 0.0 0.0 0.0 0.4 2.6 0.0 0.0 1.2 8.1 4.7 0.0 0.0 0.1 10.2 1.2 0.2 0.0 0.6 5.3 0.0 2.1 4.0 0.0 1.7 0.3 3.5 0.0 0.3 0.0 0.0 5.2 0.4 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.2 0.4 0.3 0.1 0.6 0.3 0.0 0.3 0.1 0.5 0.0 0.0 0.0 14.0 0.9 0.5 0.7 0.6 0.6 1.9 0.8 0.6 0.0 3.1 0.0 0.0 1.7 0.1 0.2 0.0 0.1 0.1 1.2 0.7 1.1 3.5 0.0 1.6 0.5 3.8 0.7 1.5 1.6 0.0 0.0 0.4 0.0 0.3 0.0 1.7 0.5 2.0 0.0 0.5 0.3 0.6 0.3 0.0 1.0 0.0 3.0 0.0 0.0 0.0 0.3 0.2 0.4 0.7 0.8 0.5 1.2 4.3 0.0 0.0 0.2 0.7 0.1 0.2 2.4 0.3 4.2 0.4 0.0 0.5 0.6 ZNF92 "HPF12, TF12" ENSG00000146757 "Zinc finger protein 92" Q03936 7 65373799-65401136 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003173 Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA003173: AB_1080744" "unprognostic (1.07e-1)" "unprognostic (1.36e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "unprognostic (8.53e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (5.48e-3)" "unprognostic (1.30e-2)" "unprognostic (3.86e-2)" "unprognostic (5.83e-2)" "unprognostic (1.40e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-3)" 2.7 4.5 2.9 5.5 3.5 16.5 10.4 5.8 4.9 5.1 1.4 4.1 4.0 3.5 4.5 5.5 3.3 4.0 2.9 2.8 3.4 3.5 3.2 3.2 10.9 3.6 3.5 5.5 3.6 4.9 2.0 3.7 3.8 3.6 4.5 3.0 2.7 3.3 2.7 3.1 4.5 2.4 4.2 6.7 5.1 5.2 3.5 10.2 6.0 4.2 9.6 3.8 2.4 4.9 7.6 5.0 21.7 21.6 5.4 6.6 10.4 6.1 4.6 6.6 9.6 9.3 10.9 29.3 11.6 3.4 10.0 7.3 17.2 4.2 10.7 11.1 11.4 13.1 2.7 9.3 2.0 16.2 12.1 5.6 3.6 6.1 4.7 8.9 8.3 15.4 17.3 11.7 9.7 2.2 23.7 17.6 29.3 7.9 6.9 21.3 12.8 9.9 7.3 15.1 18.5 14.0 9.4 14.6 7.0 20.7 10.3 21.5 6.1 7.7 6.9 4.6 8.8 7.4 6.9 41.8 5.1 12.6 6.9 4.7 1.3 3.5 2.1 1.8 4.4 8.5 3.2 3.2 1.9 7.1 3.8 4.1 1.1 7.7 2.5 1.9 5.0 1.7 2.9 3.5 5.8 4.9 2.8 3.4 3.6 3.5 3.8 4.2 3.5 4.9 13.9 9.6 1.1 3.9 44.9 5.6 7.2 3.1 8.6 8.2 15.9 11.6 5.2 5.7 6.2 5.5 0.0 6.5 35.4 4.6 11.7 7.9 1.3 5.8 11.2 9.3 7.2 13.5 7.7 4.7 5.4 9.6 6.6 11.9 11.4 17.0 9.3 2.2 4.5 5.0 11.1 8.2 6.1 6.3 3.8 2.2 7.2 11.7 5.4 3.7 10.8 11.8 14.4 12.1 12.3 6.4 7.4 6.4 17.6 6.7 2.4 5.0 2.1 5.0 0.0 11.1 10.2 25.1 24.8 5.1 3.8 4.9 23.2 16.4 6.2 7.1 ZXDA ZNF896 ENSG00000198205 "Zinc finger X-linked duplicated A" P98168 X 57905430-57910458 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA043789 Approved Approved Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA043789: AB_2678673" "unprognostic (1.53e-1)" "unprognostic (3.71e-1)" "unprognostic (1.01e-1)" "unprognostic (3.61e-3)" "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (4.22e-3)" "unprognostic (1.05e-1)" "unprognostic (3.87e-1)" "unprognostic (6.85e-3)" "unprognostic (6.50e-2)" "prognostic favorable (8.55e-4)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (1.15e-1)" "unprognostic (3.27e-2)" 2.2 2.0 1.7 1.7 2.6 2.9 2.5 4.4 2.0 2.5 0.1 1.7 1.4 2.8 2.1 1.4 3.1 1.9 2.1 1.6 1.8 2.1 1.8 1.9 2.9 2.3 2.0 4.5 2.4 2.7 1.1 1.0 2.3 2.8 1.5 1.8 1.7 2.4 3.1 1.6 1.4 2.1 1.9 3.2 2.5 0.9 2.1 2.2 3.0 3.0 2.5 1.7 1.2 3.9 1.8 1.6 0.5 2.0 2.1 2.9 1.2 1.1 2.0 1.3 1.5 0.3 1.3 4.2 2.5 2.7 1.5 1.7 1.9 2.2 1.3 3.0 3.0 0.5 1.4 0.0 3.1 0.0 0.2 2.4 4.6 2.0 4.3 2.5 2.5 2.4 0.6 0.1 3.0 1.5 1.9 1.0 2.1 0.3 1.3 2.0 1.5 1.1 1.4 1.6 0.2 1.7 2.3 1.6 1.8 2.6 2.1 1.5 1.7 2.2 4.7 0.6 1.1 0.0 0.0 2.2 1.6 1.8 1.4 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.1 0.2 0.0 1.7 2.6 4.4 2.0 1.6 1.8 2.3 2.0 2.3 1.9 2.1 3.9 4.1 0.0 0.5 1.0 5.6 9.3 4.2 1.5 8.0 2.8 1.6 1.4 2.3 2.8 1.4 1.8 4.2 0.9 1.7 0.6 0.0 1.6 0.0 1.5 1.6 3.3 1.2 0.0 2.6 0.8 0.7 2.8 3.6 1.9 1.3 1.5 0.7 0.7 1.1 3.3 3.7 1.4 2.0 1.9 2.9 0.0 2.5 1.3 3.6 3.7 0.7 1.9 0.0 2.5 5.8 0.9 0.8 1.2 4.7 2.2 0.5 1.6 1.2 2.4 0.0 2.9 2.4 0.0 0.4 1.4 6.5 0.8 3.2 1.4 1.1 2.8