Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2ML1 "CPAMD9, FLJ25179, p170" ENSG00000166535 "Alpha-2-macroglobulin like 1" A8K2U0 12 8822621-8887001 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 556.3;vagina: 204.8" "Cell type enriched" "Detected in some" 6 "Squamous epithelial cells: 127.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 39.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 10.9;hTCEpi: 5.5;SK-BR-3: 13.9" "Low region specificity" "Detected in many" "HPA038847, HPA038848" Enhanced "Secreted in other tissues" NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038847: AB_2676236, HPA038848: AB_10672654" "unprognostic (1.13e-2)" "unprognostic (7.64e-2)" "unprognostic (1.04e-2)" "unprognostic (9.46e-3)" "unprognostic (2.14e-1)" "unprognostic (5.54e-3)" "unprognostic (4.59e-2)" "unprognostic (7.58e-3)" "unprognostic (2.63e-1)" "unprognostic (1.57e-1)" "unprognostic (1.15e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-9)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (5.88e-2)" "unprognostic (2.42e-2)" 0.2 0.1 2.1 0.0 2.1 0.2 4.1 0.8 2.4 116.5 0.6 0.1 0.0 0.5 0.4 556.3 0.7 0.2 0.4 2.0 2.2 0.1 0.3 0.1 0.2 1.8 3.1 0.4 0.2 0.8 1.4 0.7 1.3 0.6 0.0 0.7 99.0 0.0 0.3 72.0 0.1 0.1 1.7 0.1 0.7 5.0 4.3 3.0 0.1 0.0 51.5 1.1 204.8 1.5 0.1 0.0 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.2 0.0 2.5 10.9 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 13.9 0.0 1.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 2.1 2.1 0.8 2.4 2.0 2.2 1.8 3.1 1.3 1.7 4.3 1.5 0.0 0.0 0.0 20.2 0.0 0.4 0.5 1.0 1.8 0.7 0.3 0.1 0.7 0.0 2.2 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.4 4.4 0.9 0.3 0.0 0.0 4.9 0.0 0.5 0.4 0.0 11.9 0.0 0.8 0.0 0.0 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.0 0.0 0.0 1.2 0.0 2.0 0.5 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.3 0.0 0.4 0.3 1.0 0.4 127.6 12.6 0.1 0.1 1.9 0.0 8.2 ABLIM1 "ABLIM, LIMAB1, limatin" ENSG00000099204 "Actin binding LIM protein 1" O14639 10 114431113-114768061 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 875.6;Cardiomyocytes: 592.5;Peritubular cells: 413.0;Squamous epithelial cells: 481.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 139.1" "Group enriched" "Detected in many" 7 "B-cells: 52.2;NK-cells: 63.6;T-cells: 139.1" "Cell line enhanced" "Detected in many" "hTCEpi: 164.1;OE19: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038951, HPA038952" Approved Supported Cytosol NA NA 6000 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA038951: AB_10673017, HPA038952: AB_10670915" "unprognostic (2.25e-2)" "unprognostic (3.96e-2)" "unprognostic (2.91e-1)" "unprognostic (1.26e-1)" "unprognostic (5.89e-3)" "unprognostic (1.07e-2)" "unprognostic (3.19e-2)" "unprognostic (5.07e-2)" "unprognostic (4.39e-2)" "unprognostic (1.05e-1)" "unprognostic (3.20e-2)" "unprognostic (3.23e-1)" "prognostic favorable (2.72e-5)" "unprognostic (2.77e-2)" "unprognostic (1.92e-1)" "unprognostic (3.22e-1)" "unprognostic (5.87e-2)" 73.3 93.4 71.0 35.7 67.6 13.6 54.8 277.3 59.4 44.4 76.2 46.7 37.3 37.3 26.7 205.6 51.3 33.5 268.6 58.5 78.3 54.7 28.3 54.5 50.0 90.5 65.1 233.6 32.1 42.3 22.0 31.5 74.9 24.0 57.8 110.1 98.2 26.5 75.1 97.5 34.2 29.3 85.2 20.1 120.7 41.3 67.0 56.8 112.9 111.6 89.1 42.0 89.4 73.2 48.2 34.7 120.2 27.2 1.1 0.4 1.5 9.6 3.2 2.4 6.7 49.0 76.7 61.8 128.7 11.1 18.1 101.4 41.1 66.2 3.1 21.2 35.5 0.5 96.0 128.8 0.5 24.6 0.4 1.5 164.1 18.1 52.1 50.3 47.5 21.4 0.2 93.3 0.5 17.5 5.0 10.8 47.0 159.5 38.4 2.1 29.3 80.3 38.4 105.6 41.7 51.4 40.4 59.2 21.0 60.0 30.7 0.3 32.1 0.1 43.1 1.1 18.3 0.5 0.3 140.0 2.3 54.0 0.9 11.9 0.2 0.8 28.6 0.2 55.5 40.9 53.9 32.8 0.4 52.2 139.1 91.0 2.4 63.6 0.3 0.4 33.7 48.1 71.0 67.6 277.3 59.4 58.5 78.3 90.5 65.1 74.9 85.2 67.0 73.2 218.9 317.3 36.0 875.6 47.1 86.8 42.2 35.7 306.2 54.5 27.6 29.5 592.5 51.5 97.1 53.3 18.8 1.5 43.2 59.8 35.2 37.8 110.7 88.4 32.7 107.3 16.8 7.4 236.0 54.5 0.8 126.1 225.3 30.9 1.3 119.6 55.6 51.4 0.6 58.9 326.0 101.7 16.2 1.3 18.4 133.7 227.7 9.4 21.4 213.6 4.3 54.7 27.8 50.3 9.2 59.6 34.7 413.0 22.7 49.8 46.7 42.1 79.3 96.7 0.0 155.8 22.0 3.9 4.7 481.0 189.4 0.7 62.8 53.6 51.4 164.0 ADAT3 TAD3 ENSG00000213638 "Adenosine deaminase tRNA specific 3" 19 1905399-1913447 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 9.1;Gastric mucus-secreting cells: 8.2;Squamous epithelial cells: 13.7;Suprabasal keratinocytes: 11.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 13.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA058899 Uncertain Approved Nucleoplasm No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA058899: AB_2683847" "unprognostic (1.79e-1)" "unprognostic (7.99e-2)" "unprognostic (1.57e-1)" "unprognostic (3.61e-3)" "unprognostic (4.43e-2)" "prognostic favorable (6.13e-4)" "unprognostic (1.48e-4)" "unprognostic (2.18e-1)" "unprognostic (1.63e-1)" "unprognostic (1.38e-1)" "unprognostic (4.78e-3)" "unprognostic (5.27e-2)" "unprognostic (2.21e-2)" "prognostic favorable (6.98e-4)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "unprognostic (9.55e-3)" 3.3 4.6 1.6 0.8 3.1 0.7 3.1 2.8 2.6 4.2 1.2 7.7 7.5 3.5 0.2 10.6 3.7 0.2 2.8 1.1 1.4 7.9 5.4 3.7 0.5 5.6 3.1 3.1 6.3 0.1 3.3 0.2 4.0 6.4 0.7 0.0 8.1 0.4 1.9 13.9 6.6 0.1 3.1 6.1 4.7 2.9 3.3 0.1 4.5 0.2 0.3 2.8 5.3 6.1 4.9 1.2 0.7 1.0 0.4 0.0 5.9 1.7 0.3 0.6 0.9 1.9 1.5 2.8 0.7 0.2 0.3 3.1 0.2 0.2 0.0 6.9 12.5 0.7 3.7 2.5 0.2 1.3 8.8 0.0 0.2 0.8 0.0 0.1 0.6 0.8 8.1 1.5 0.4 1.0 2.3 4.2 6.5 0.2 8.4 7.6 1.1 4.8 0.7 1.2 2.6 6.4 2.1 5.0 2.5 0.3 3.9 1.0 1.6 0.6 2.8 2.4 3.7 2.7 2.6 2.5 0.5 1.3 1.6 0.2 1.2 0.0 1.3 0.7 1.4 0.9 2.0 2.3 1.7 2.5 1.4 2.3 0.3 4.1 1.1 13.2 2.6 0.8 1.6 3.1 2.8 2.6 1.1 1.4 5.6 3.1 4.0 3.1 3.3 6.1 1.1 0.0 1.5 0.0 2.9 6.1 1.0 1.0 9.1 0.0 4.0 1.8 0.6 1.5 0.5 0.0 0.0 1.8 5.5 4.1 1.9 1.5 0.1 6.3 1.2 1.4 1.2 0.4 0.0 0.7 2.4 1.6 8.2 3.1 0.0 0.5 2.2 0.8 1.8 0.0 0.0 1.1 0.0 1.4 3.1 0.6 0.0 2.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 4.3 0.7 6.4 0.3 4.2 4.0 2.3 0.0 0.0 0.8 1.2 0.8 3.1 13.7 11.1 4.5 3.6 0.8 1.7 1.2 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 89.0;Club cells: 64.1;Squamous epithelial cells: 209.1" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC TERT1: 1.0;HaCaT: 1.2" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 196.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.2 0.0 0.0 38.1 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 89.0 21.1 0.0 0.0 0.0 0.2 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 18.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.6 0.0 0.0 26.2 0.0 0.0 0.0 2.3 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 1.0 ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 196.1;Basal keratinocytes: 387.5;Basal respiratory cells: 146.6;Squamous epithelial cells: 276.0;Suprabasal keratinocytes: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 72.4;hTERT-HME1: 74.1;PC-3: 31.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003431, HPA075322" Uncertain Uncertain Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA003431: AB_1845333, HPA075322: " "unprognostic (2.28e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-3)" "unprognostic (5.54e-2)" "unprognostic (2.34e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (3.15e-9)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" 19.5 1.6 4.5 3.2 4.7 12.5 18.7 5.1 4.4 13.5 1.8 2.3 1.9 2.3 1.7 15.1 4.1 3.8 6.7 5.3 4.2 1.1 14.2 19.5 4.1 6.0 5.6 0.9 1.2 2.2 0.3 9.9 6.2 9.0 2.8 0.6 4.2 1.5 11.7 21.8 2.1 3.7 6.2 7.9 7.5 0.5 7.1 2.7 1.0 8.6 6.0 6.8 7.2 7.6 23.3 0.1 0.1 0.0 0.8 0.2 0.0 4.3 13.2 6.0 6.7 0.0 9.7 0.1 6.1 1.3 21.5 20.0 0.0 27.9 6.9 0.0 0.6 0.0 5.1 0.0 0.6 0.1 11.0 0.1 72.4 2.0 74.1 5.0 2.8 0.0 0.1 8.3 16.0 0.0 0.0 12.9 0.4 0.2 31.2 6.7 4.1 13.0 3.2 5.8 0.1 0.1 5.4 0.4 2.0 2.5 0.0 7.0 12.3 0.0 5.0 7.2 3.5 1.9 0.0 0.2 0.0 15.1 2.6 16.5 21.8 67.8 151.4 37.1 112.3 21.5 34.3 93.0 24.7 15.6 5.8 53.3 35.4 37.2 53.3 28.4 2.3 53.4 4.5 4.7 5.1 4.4 5.3 4.2 6.0 5.6 6.2 6.2 7.1 7.6 196.1 112.2 31.6 1.6 16.5 387.5 36.6 146.6 127.5 0.5 23.3 15.2 18.6 0.0 67.4 0.0 0.0 0.4 59.2 3.7 0.0 2.4 0.5 3.2 0.5 40.3 3.0 1.3 0.0 0.2 0.3 6.2 35.7 3.0 118.6 0.1 6.8 14.1 17.7 0.0 0.0 3.1 16.2 20.8 54.9 0.7 0.0 21.1 30.2 15.9 4.0 4.1 90.6 0.0 0.1 8.6 0.1 0.0 23.2 23.5 0.1 0.1 27.8 5.0 0.0 19.8 9.6 0.7 0.1 276.0 245.4 0.5 40.1 0.1 3.5 61.5 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 285.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 75.2 203.0 23.1 15.2 32.5 9.3 34.9 24.8 27.7 49.4 71.7 49.6 68.1 29.4 41.7 131.3 38.3 70.5 44.6 29.0 27.9 173.0 288.6 59.1 14.9 23.3 26.3 32.3 52.3 40.6 21.9 11.8 23.5 75.0 36.5 40.8 61.7 41.5 53.0 207.6 71.8 30.2 25.1 19.4 81.5 26.9 24.8 23.0 75.1 100.9 36.4 24.2 40.5 33.6 27.7 147.0 29.2 58.5 88.7 89.4 19.1 12.3 29.9 24.4 27.6 63.2 52.5 12.3 35.9 50.5 29.3 99.0 59.8 125.2 19.9 36.2 42.5 5.3 120.9 142.8 12.2 30.6 5.4 42.9 137.6 22.9 12.2 49.7 49.2 25.5 2.2 0.6 37.3 45.3 0.7 25.2 32.3 285.4 78.5 38.6 64.1 25.3 17.5 132.3 46.3 30.4 98.9 38.4 35.3 152.2 78.1 35.0 46.7 10.1 28.7 68.8 45.6 11.3 28.6 15.5 47.4 0.3 48.3 0.8 21.1 17.5 6.3 18.3 9.9 5.2 6.0 6.1 20.7 4.9 6.8 6.3 2.2 15.0 20.6 1.3 11.3 11.0 23.1 32.5 24.8 27.7 29.0 27.9 23.3 26.3 23.5 25.1 24.8 33.6 22.1 176.3 86.5 14.7 13.3 57.1 143.9 85.1 287.4 15.3 13.6 24.0 54.1 105.8 86.5 33.1 12.5 12.5 8.2 48.9 43.0 97.5 79.6 47.5 13.4 19.5 16.2 8.2 30.5 52.0 4.6 39.9 87.7 36.9 29.7 34.6 13.6 116.7 24.6 6.7 20.1 27.7 26.4 21.7 15.1 19.5 55.9 23.5 7.2 13.1 25.7 105.9 8.2 19.6 29.1 43.9 28.7 80.5 28.6 104.2 90.6 119.2 59.2 21.4 13.1 70.1 22.1 15.5 24.0 232.6 90.2 1.4 13.2 29.1 46.0 51.4 ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662160-67681224 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 73.0;esophagus: 152.2;skin 1: 123.0;vagina: 41.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 26.2;Endometrial ciliated cells: 12.6;Glandular and luminal cells: 28.1;Squamous epithelial cells: 53.3;Suprabasal keratinocytes: 14.8;Syncytiotrophoblasts: 14.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 71.9;SK-BR-3: 70.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045132 Approved NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA045132: AB_10795993" "unprognostic (2.25e-1)" "unprognostic (2.41e-1)" "unprognostic (1.65e-1)" "unprognostic (8.65e-2)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (5.92e-2)" 0.3 0.0 0.1 0.1 0.0 0.2 73.0 0.0 0.0 14.4 0.0 0.1 0.1 0.8 6.8 152.2 4.6 0.3 0.1 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.3 5.2 0.1 3.2 0.0 3.3 0.1 0.5 17.3 4.8 0.3 123.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 2.4 0.0 0.0 21.1 8.3 41.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 7.9 0.0 0.0 0.1 0.0 1.3 3.5 3.3 0.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.9 6.8 0.0 0.1 9.0 0.0 0.0 0.0 1.9 0.0 13.0 0.0 0.1 0.0 70.7 0.1 0.4 15.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 1.7 1.2 4.9 1.2 0.0 26.2 7.2 0.4 0.0 7.3 5.5 0.0 10.6 0.2 0.0 1.9 1.1 0.0 12.6 2.6 0.2 0.0 0.0 0.1 0.2 10.6 0.2 0.0 28.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.0 0.0 0.8 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 53.3 14.8 14.6 0.2 0.0 0.0 7.6 ANXA8 ANX8 ENSG00000265190 "Annexin A8" P13928 10 47460162-47484158 "Predicted intracellular proteins" "Blood coagulation, Hemostasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 217.6;skin 1: 266.2;vagina: 110.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.3;Astrocytes: 38.8;Club cells: 40.7;Excitatory neurons: 47.8;Fibroblasts: 34.5;Inhibitory neurons: 41.0;Microglial cells: 35.6;Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 48.1;Squamous epithelial cells: 63.6" "Group enriched" "Detected in many" 4 "cervical cancer: 14.3;head and neck cancer: 16.1;lung cancer: 4.3;urothelial cancer: 11.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 394.3;HBEC3-KT: 622.3;hTCEpi: 357.6;hTERT-HME1: 134.2;RT4: 159.6" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (8.32e-4)" "unprognostic (2.52e-1)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (5.94e-2)" "unprognostic (2.88e-2)" "unprognostic (2.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.19e-1)" "unprognostic (7.55e-15)" "unprognostic (1.04e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.39e-1)" 73.3 0.7 0.5 0.1 0.5 0.7 11.7 0.7 1.1 49.6 0.6 0.5 0.0 0.1 1.0 217.6 3.7 0.4 4.4 0.6 0.3 0.0 1.8 13.1 0.0 1.0 0.8 1.3 0.3 0.0 0.3 30.9 0.8 12.4 0.1 0.0 47.3 9.8 0.4 266.2 0.2 0.0 0.6 0.2 0.4 0.8 1.5 4.8 0.2 0.2 46.6 66.4 110.7 0.9 123.4 16.2 0.0 0.0 0.0 0.0 33.7 2.3 0.3 0.0 0.0 8.7 35.0 0.0 2.5 1.0 1.8 394.3 0.0 622.3 0.0 27.9 0.0 0.0 39.6 0.0 26.2 0.0 1.3 0.2 357.6 0.2 134.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 37.2 0.1 4.0 0.0 0.0 0.5 0.0 0.0 159.6 0.0 0.0 56.4 16.4 0.3 8.7 0.1 3.5 0.0 0.0 39.5 0.7 2.4 0.2 0.1 0.2 4.4 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.5 0.7 1.1 0.6 0.3 1.0 0.8 0.8 0.6 1.5 0.9 0.1 99.3 7.3 38.8 0.0 1.1 10.3 1.6 2.8 0.0 4.9 3.4 2.6 7.2 40.7 3.7 0.0 14.7 0.1 1.0 0.0 3.1 0.6 2.1 0.0 0.5 0.0 0.0 47.8 0.4 6.7 34.5 0.0 0.2 1.3 0.1 0.0 0.0 0.6 0.0 41.0 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.0 35.6 0.1 0.0 0.0 50.8 48.1 17.3 0.0 0.0 0.0 8.5 1.5 0.0 14.2 0.0 0.0 0.0 0.6 0.2 1.4 63.6 2.0 6.2 0.3 0.1 0.2 17.2 ANXA8L1 "ANXA8L2, bA145E20.2, bA301J7.3" ENSG00000264230 "Annexin A8 like 1" Q5VT79 10 46375627-46391784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 195.2;skin 1: 325.4;vagina: 100.5" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 118.7" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2;head and neck cancer: 5.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 374.5;HBEC3-KT: 485.0;hTCEpi: 140.1;SiHa: 116.6" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (3.67e-3)" "unprognostic (4.56e-3)" "unprognostic (9.14e-3)" "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-2)" "unprognostic (8.05e-2)" "unprognostic (6.94e-3)" "unprognostic (8.33e-5)" "unprognostic (3.43e-1)" "unprognostic (8.26e-10)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" 39.8 0.2 0.0 0.0 0.0 1.2 21.9 0.0 0.1 45.2 0.0 0.3 0.0 0.1 0.0 195.2 6.1 0.1 2.9 0.0 0.0 0.0 1.1 16.5 0.0 0.0 0.0 0.9 0.3 0.0 0.2 24.1 0.0 6.8 0.0 0.0 40.8 4.5 1.1 325.4 0.1 0.0 0.0 0.1 0.3 0.8 0.0 4.3 0.1 0.0 35.1 37.4 100.5 0.0 70.1 18.2 0.0 0.0 0.0 0.0 24.8 0.9 0.1 0.0 0.0 1.9 12.6 0.0 0.6 0.3 0.5 374.5 0.0 485.0 0.0 28.9 0.0 0.0 33.3 0.0 9.3 0.0 0.7 0.0 140.1 0.2 58.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 70.2 0.2 0.7 0.0 0.0 0.8 0.0 0.0 76.0 0.1 0.0 116.6 12.0 0.0 7.2 0.0 0.7 0.0 0.1 12.2 0.1 0.3 0.0 0.1 0.0 2.8 0.1 0.2 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.9 1.1 0.0 0.0 0.0 3.0 0.2 11.4 1.6 2.3 2.4 3.7 18.6 19.9 0.0 0.0 14.8 0.0 3.0 0.0 0.7 0.4 1.0 0.0 0.9 0.0 0.0 0.0 0.2 11.4 12.8 5.6 0.1 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.7 1.4 0.0 1.2 2.5 5.2 0.0 10.9 0.2 13.1 0.0 1.5 0.3 2.4 118.7 1.1 6.3 0.6 0.0 0.2 5.9 ARF5 ENSG00000004059 "ADP ribosylation factor 5" P84085 7 127588386-127591700 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 3900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (6.72e-3)" "unprognostic (2.34e-2)" "unprognostic (1.67e-2)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (5.81e-3)" "unprognostic (9.41e-2)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (7.02e-2)" "unprognostic (1.02e-1)" "unprognostic (9.69e-2)" "unprognostic (1.50e-1)" "unprognostic (1.26e-2)" "unprognostic (3.95e-1)" "unprognostic (2.46e-2)" 100.2 93.7 139.3 72.6 147.7 143.0 99.8 128.4 200.6 100.7 124.4 108.3 92.3 104.8 114.1 227.5 97.5 81.7 118.6 152.0 137.2 125.8 139.0 90.8 102.7 133.8 132.0 72.1 168.1 104.0 100.2 69.3 135.1 98.7 61.3 22.9 103.1 71.1 131.9 199.8 98.5 66.3 131.9 105.8 117.8 82.9 135.2 95.8 80.5 101.4 74.6 92.5 122.1 133.4 157.4 148.9 120.1 386.5 101.6 159.1 163.3 43.9 129.6 118.7 135.8 232.0 211.4 114.7 64.4 132.6 135.9 117.5 92.4 198.0 38.4 104.9 222.8 44.9 137.5 160.2 150.1 69.7 100.1 163.1 196.2 77.7 75.8 94.5 173.2 164.1 105.1 124.1 116.9 531.2 249.0 303.7 179.9 157.1 191.7 148.3 73.9 245.6 198.2 158.7 349.1 226.2 142.8 461.8 116.1 77.6 123.9 108.0 103.7 177.3 75.3 128.0 101.9 115.2 77.5 153.9 181.1 142.0 154.6 289.0 321.4 279.7 144.3 270.3 146.7 129.5 151.1 148.4 409.6 117.2 112.0 122.2 447.5 156.5 216.2 259.6 181.8 381.8 139.3 147.7 128.4 200.6 152.0 137.2 133.8 132.0 135.1 131.9 135.2 133.4 110.3 3.2 12.1 28.4 81.3 105.7 72.9 217.1 130.9 14.8 111.8 180.7 2.0 91.5 83.0 112.2 0.0 151.6 89.7 89.4 201.5 107.8 39.3 90.3 95.7 73.9 119.9 102.2 46.5 90.7 125.0 82.2 135.5 88.2 21.0 91.1 75.7 51.6 102.7 20.2 42.5 108.8 140.4 129.6 221.9 40.7 93.2 123.9 149.4 28.1 118.6 27.6 82.4 27.2 36.2 86.4 134.0 94.8 75.1 57.2 147.5 160.0 58.4 11.9 72.3 58.7 85.4 99.2 116.7 248.3 153.4 146.3 100.2 69.1 125.4 93.4 ARL4D ARF4L ENSG00000175906 "ADP ribosylation factor like GTPase 4D" P49703 17 43398993-43401137 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.3;Early spermatids: 220.8;Rod photoreceptor cells: 259.6;Squamous epithelial cells: 223.4;Suprabasal keratinocytes: 254.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 32.3;naive B-cell: 36.1" "Lineage enriched" "Detected in all" 4 "B-cells: 36.1" "Cell line enhanced" "Detected in many" "HHSteC: 57.1;hTCEpi: 76.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 8.7;cerebral cortex: 8.8;hippocampal formation: 5.7;olfactory bulb: 4.2;spinal cord: 5.4" HPA060379 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "Golgi apparatus" "HPA060379: AB_2684269" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (2.34e-2)" "prognostic favorable (1.16e-5)" "unprognostic (7.71e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.47e-1)" "unprognostic (4.59e-2)" "unprognostic (4.45e-1)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (7.87e-2)" "unprognostic (2.00e-3)" "unprognostic (3.49e-2)" "unprognostic (6.48e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (9.25e-4)" 21.0 4.3 7.9 2.2 8.7 0.9 7.2 9.1 11.6 29.3 12.6 27.9 2.0 20.2 4.7 82.2 22.1 7.3 12.7 8.1 7.1 30.5 56.4 16.2 1.6 5.6 5.7 9.7 2.2 8.1 21.6 7.7 5.7 11.0 3.5 85.1 16.9 15.2 1.9 44.9 6.0 14.8 5.4 16.7 7.6 32.1 5.7 1.6 38.3 3.4 3.0 28.5 39.5 9.3 8.7 10.9 6.7 5.2 12.5 17.2 3.1 21.0 21.5 14.6 18.8 9.7 37.7 0.1 10.3 22.6 10.0 23.4 4.5 32.0 10.0 1.9 7.5 0.7 8.7 22.5 57.1 2.4 2.1 19.2 76.1 21.3 45.8 13.2 6.3 2.3 1.4 0.4 14.3 0.5 5.4 5.0 7.1 0.8 10.1 9.1 1.5 1.0 24.9 18.8 7.9 5.6 16.5 0.4 15.8 14.4 30.6 8.5 1.3 21.0 6.7 27.2 6.4 2.1 1.1 0.0 25.8 1.9 7.1 0.1 2.8 2.1 5.1 4.3 3.2 32.3 4.2 4.7 8.4 36.1 4.6 5.2 0.0 2.1 1.4 2.5 1.0 4.6 7.9 8.7 9.1 11.6 8.1 7.1 5.6 5.7 5.7 5.4 5.7 9.3 28.8 0.0 1.7 0.7 37.9 224.3 41.4 142.2 132.1 155.5 35.3 60.6 12.7 5.7 49.5 132.4 116.7 39.9 37.4 1.5 76.3 2.3 220.8 55.5 33.3 32.2 11.9 4.0 9.1 1.8 24.1 52.3 5.6 69.6 0.0 20.7 22.9 29.7 8.1 16.8 9.3 5.4 26.4 4.1 77.9 55.3 15.8 16.6 26.6 1.0 1.4 70.1 2.1 2.5 1.3 3.7 0.9 22.6 1.4 9.5 0.3 17.6 7.6 259.6 13.1 11.1 45.1 25.0 9.2 223.4 254.6 105.5 31.7 19.3 4.6 78.1 BARX2 ENSG00000043039 "BARX homeobox 2" Q9UMQ3 11 129375848-129452279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.0;salivary gland: 131.4;vagina: 72.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 128.5;Breast glandular cells: 50.4;Squamous epithelial cells: 136.4;Suprabasal keratinocytes: 82.5;Urothelial cells: 84.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HDLM-2: 163.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.8;hippocampal formation: 1.7" "CAB033311, HPA064966, HPA068414" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB033311: AB_781574, HPA064966: , HPA068414: AB_2685984" "unprognostic (4.25e-2)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.22e-5)" "unprognostic (3.85e-2)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (1.43e-3)" "unprognostic (4.80e-1)" "unprognostic (1.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.15e-1)" "unprognostic (8.39e-2)" "unprognostic (3.48e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.06e-4)" 0.3 0.0 0.1 1.3 0.3 0.0 14.9 1.1 0.3 24.2 5.5 7.0 17.9 0.1 0.2 158.0 16.7 4.7 0.2 0.3 0.4 5.4 0.0 0.3 0.7 3.0 1.6 0.0 10.3 0.3 1.7 3.6 3.2 4.8 4.9 0.2 131.4 0.6 2.2 34.8 13.0 0.2 1.8 0.0 6.4 2.4 0.4 0.4 0.3 39.3 8.8 0.4 72.2 2.9 23.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.3 0.0 1.0 20.9 0.0 5.1 0.0 163.7 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.1 0.0 3.9 0.0 6.2 0.0 0.0 0.0 20.6 0.9 0.0 0.0 39.8 0.0 0.3 0.2 0.0 0.0 19.4 0.1 0.4 3.8 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.1 0.3 0.3 0.4 3.0 1.6 3.2 1.8 0.4 2.9 0.2 0.0 1.1 0.3 0.5 43.1 128.5 8.7 3.4 0.6 50.4 16.9 0.5 4.3 8.0 0.0 0.0 13.4 0.8 29.4 7.9 23.7 7.2 11.3 0.6 1.2 1.8 0.0 1.8 0.7 5.8 2.7 6.6 4.6 0.0 0.0 0.0 0.2 1.9 0.0 0.3 13.4 0.0 0.3 2.2 1.6 0.0 0.7 10.6 0.0 0.1 0.7 0.0 0.0 0.3 6.2 29.8 0.4 0.9 25.6 34.0 3.4 11.8 0.3 0.0 0.6 1.7 0.1 5.3 136.4 82.5 4.2 1.7 0.0 19.4 84.8 BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 23.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 40.8;Basal squamous epithelial cells: 41.5;Fibroblasts: 17.0;Squamous epithelial cells: 22.5;Suprabasal keratinocytes: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.0;fHDF/TERT166: 18.8;HHSteC: 29.2;hTEC/SVTERT24-B: 29.2;U-2197: 27.9;U-87 MG: 90.1" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" 10.7 0.2 0.4 5.2 0.7 0.0 1.2 1.3 0.9 6.9 0.3 4.2 1.8 0.9 0.6 13.4 5.1 14.1 1.6 0.5 0.3 8.3 0.2 1.3 0.1 0.5 0.4 0.4 6.5 0.0 0.2 0.7 0.5 1.5 2.7 0.2 1.9 0.2 0.1 3.3 3.6 6.0 0.3 0.1 4.5 2.3 0.4 0.1 1.1 0.5 0.4 23.4 7.4 0.6 0.5 1.4 0.0 1.2 2.9 9.9 0.1 2.3 32.0 3.1 0.5 0.0 0.6 0.0 0.1 18.8 1.4 2.4 0.0 0.4 5.0 0.3 0.1 0.0 2.7 0.0 29.2 0.0 0.1 1.0 2.4 29.2 0.6 0.2 0.0 0.0 0.0 0.1 4.2 0.4 0.0 0.0 0.0 1.7 0.2 0.0 7.2 0.2 0.2 0.1 0.7 0.0 8.2 2.4 0.0 0.3 0.0 0.0 0.0 9.5 0.6 27.9 1.8 4.6 9.3 0.0 90.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 1.3 0.9 0.5 0.3 0.5 0.4 0.5 0.3 0.4 0.6 1.4 0.0 0.5 0.0 0.0 40.8 2.9 9.0 41.5 1.7 0.0 0.3 0.8 0.0 3.2 0.0 0.0 0.3 0.0 5.5 7.9 2.3 1.1 0.9 3.7 5.0 0.0 0.0 0.4 1.2 1.4 17.0 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 6.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.3 4.9 0.4 0.0 1.6 2.3 0.1 3.3 0.1 0.0 1.6 2.5 0.9 1.3 22.5 17.2 1.5 0.2 0.0 0.4 2.8 BHLHE40 "BHLHB2, Clast5, DEC1, SHARP2, STRA13" ENSG00000134107 "Basic helix-loop-helix family member e40" O14503 3 4979437-4985323 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 386.7;granulocytes: 439.2;Squamous epithelial cells: 517.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 101.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 488.2;Karpas-707: 228.4;U-87 MG: 218.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028922 Uncertain Supported "Nuclear bodies" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA028922: AB_2672828" "unprognostic (8.64e-3)" "unprognostic (5.21e-2)" "unprognostic (1.03e-2)" "unprognostic (1.39e-1)" "unprognostic (8.58e-3)" "unprognostic (7.95e-2)" "unprognostic (2.90e-1)" "unprognostic (2.88e-3)" "unprognostic (1.31e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (8.74e-4)" "unprognostic (5.45e-2)" "unprognostic (3.36e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (5.95e-2)" "unprognostic (7.03e-3)" 154.1 99.0 38.5 52.9 38.4 188.2 200.0 36.1 48.7 141.6 41.4 67.9 30.8 67.6 34.6 353.2 61.5 100.4 153.4 38.1 32.8 151.4 187.9 112.1 52.4 52.0 47.5 76.0 79.8 67.5 92.6 72.2 39.3 98.1 47.4 118.3 117.3 32.5 251.7 207.2 42.6 65.2 40.5 26.9 43.5 14.1 49.6 40.6 82.7 46.8 50.7 172.1 272.3 37.0 40.4 53.4 0.1 14.7 30.8 23.8 78.6 7.5 19.7 7.7 30.2 3.4 39.7 0.2 19.6 14.2 118.9 31.5 6.6 108.0 13.2 488.2 4.7 9.8 39.6 11.9 29.7 25.5 192.8 55.1 63.3 88.9 25.4 53.4 30.0 1.7 53.9 228.4 20.3 28.4 3.9 10.8 2.9 45.6 87.1 0.7 17.6 23.0 74.4 7.9 0.8 1.7 132.6 34.2 40.0 45.9 78.6 38.8 39.7 30.4 29.3 28.9 50.0 175.9 82.8 1.6 218.0 19.8 15.3 101.4 9.7 54.5 24.7 4.9 24.9 7.7 13.1 16.6 15.2 4.5 2.9 10.1 14.3 54.9 0.5 19.9 0.9 11.9 38.5 38.4 36.1 48.7 38.1 32.8 52.0 47.5 39.3 40.5 49.6 37.0 172.5 67.3 191.3 32.3 24.9 165.4 112.8 330.5 373.3 15.4 136.6 74.7 65.0 40.0 297.7 46.0 0.0 32.0 159.8 52.9 11.7 75.2 0.3 210.2 69.6 161.6 10.7 2.5 36.6 72.5 89.3 102.6 68.3 386.7 439.2 0.5 75.0 56.5 38.3 10.1 4.5 32.6 136.3 52.1 354.0 1.7 7.2 117.9 108.5 27.2 42.9 95.1 44.3 11.1 3.3 138.8 37.9 3.8 38.0 61.1 8.8 23.1 102.1 11.5 6.6 55.3 94.4 0.2 0.4 517.2 262.0 158.4 97.8 0.3 24.4 129.4 BICD2 KIAA0699 ENSG00000185963 "BICD cargo adaptor 2" Q8TD16 9 92711363-92764833 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Squamous epithelial cells: 103.2;Suprabasal keratinocytes: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023013, HPA024452" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane, Cytosol" "HPA023013: AB_1845352, HPA024452: AB_1845353" "unprognostic (9.99e-3)" "unprognostic (1.98e-1)" "unprognostic (7.84e-3)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "unprognostic (2.86e-1)" "unprognostic (2.37e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (6.54e-3)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" 15.4 10.6 11.4 13.5 10.0 12.0 10.9 10.9 10.5 20.8 7.8 18.5 4.6 15.5 6.0 47.0 12.8 9.4 19.8 11.1 8.6 9.1 8.5 16.0 14.7 11.0 9.8 12.5 8.9 17.7 6.0 10.4 10.3 11.3 5.0 6.5 14.6 13.1 22.3 63.4 10.4 13.7 10.5 17.3 9.5 9.4 10.0 13.8 10.0 15.3 16.8 15.2 30.9 12.3 32.6 26.5 19.2 19.8 36.6 25.1 27.1 30.8 22.2 17.2 13.6 15.6 14.4 36.3 19.5 34.4 22.0 99.4 21.8 49.1 19.4 17.4 23.5 19.2 25.6 21.7 21.8 26.9 30.0 25.8 67.1 28.8 22.0 20.4 26.0 15.4 19.3 27.5 38.1 21.4 25.6 16.7 13.3 23.8 32.0 27.8 41.8 19.3 27.8 27.0 13.4 20.7 21.7 19.9 14.3 19.2 8.2 12.3 34.9 31.8 21.1 53.9 33.9 22.5 17.5 31.9 26.9 16.3 28.4 1.6 3.4 4.4 1.2 3.6 1.2 1.8 1.4 1.6 3.8 2.0 1.3 1.2 7.5 1.1 5.9 3.2 0.9 1.7 11.4 10.0 10.9 10.5 11.1 8.6 11.0 9.8 10.3 10.5 10.0 12.3 21.7 28.9 12.7 14.7 27.6 73.7 17.1 19.2 83.6 12.8 11.4 10.2 54.5 8.6 16.2 7.3 6.2 8.5 26.1 3.4 3.9 10.1 6.5 21.3 26.7 26.4 10.8 16.0 16.2 5.1 6.5 26.0 5.6 21.1 24.1 13.0 19.2 7.5 14.2 15.2 14.0 1.9 12.2 32.4 30.2 7.6 21.1 40.7 16.0 19.7 38.9 22.0 7.2 9.5 18.5 8.5 3.6 33.4 22.1 18.7 0.8 6.7 14.0 6.4 19.7 23.0 33.1 9.7 8.4 103.2 130.8 7.3 17.2 13.8 3.6 20.3 BNIPL "BNIP-S, BNIP-Salpha, BNIP-Sbeta, BNIPl-1, BNIPL-2, PP753" ENSG00000163141 "BCL2 interacting protein like" Q7Z465 1 151036321-151047720 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 128.5;skin 1: 181.4;vagina: 69.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 17.2;Squamous epithelial cells: 42.7;Suprabasal keratinocytes: 57.1;Urothelial cells: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "T-47d: 46.1" "Group enriched" "Detected in some" 9 "basal ganglia: 1.6;cerebellum: 2.4" "Not detected" "Not detected" HPA019946 Uncertain Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA019946: AB_2732424" "unprognostic (2.62e-1)" "unprognostic (7.59e-3)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.50e-4)" "unprognostic (6.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.32e-3)" "unprognostic (3.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.88e-4)" "unprognostic (1.91e-1)" "unprognostic (8.43e-11)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" "prognostic favorable (4.32e-4)" "unprognostic (6.81e-2)" 0.4 0.3 0.9 0.4 1.0 0.6 15.6 3.0 1.3 25.1 0.7 0.4 0.3 0.3 0.2 128.5 2.7 0.3 0.7 0.9 1.0 2.9 1.2 9.4 0.6 1.5 1.0 0.6 0.4 1.1 0.6 0.5 1.1 12.5 0.2 0.8 22.9 4.7 1.6 181.4 0.5 0.1 0.7 1.1 1.4 4.3 1.0 0.7 7.4 0.1 10.1 9.7 69.7 1.1 0.4 0.4 0.6 0.6 0.4 0.4 0.7 0.3 0.0 0.3 0.2 1.5 0.4 0.7 0.7 0.0 0.1 1.5 0.9 0.2 0.6 1.1 1.0 1.2 0.8 0.2 0.1 0.6 0.6 0.0 3.1 0.2 0.3 1.0 0.0 1.1 0.6 0.5 0.3 2.0 0.7 1.2 0.5 1.0 0.4 0.3 0.3 0.4 0.6 0.4 1.3 0.6 0.5 0.9 0.3 2.2 46.1 0.4 1.1 0.7 0.5 0.2 0.1 1.7 1.3 3.9 0.1 0.3 0.8 0.5 0.1 0.1 0.3 0.1 0.2 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.1 0.1 0.1 0.0 0.1 0.9 1.0 3.0 1.3 0.9 1.0 1.5 1.0 1.1 0.7 1.0 1.1 0.4 16.0 17.2 0.0 0.3 15.3 6.1 3.9 12.5 0.4 14.2 6.1 0.3 0.0 11.0 11.0 0.0 1.6 1.2 0.3 0.0 0.0 7.6 1.1 1.3 0.8 0.0 0.0 1.1 0.0 0.4 0.9 0.0 1.1 0.0 0.4 2.5 0.1 0.3 0.0 1.2 0.3 2.0 0.6 5.5 1.3 0.9 1.9 3.6 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.1 0.0 0.6 5.5 0.8 0.3 12.8 1.5 0.0 0.9 1.2 0.9 0.3 42.7 57.1 2.6 1.3 0.2 0.4 24.4 CALML3 CLP ENSG00000178363 "Calmodulin like 3" P27482 10 5524961-5526771 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 507.1;skin 1: 179.0;vagina: 200.8" "Cell type enriched" "Detected in some" 8 "Squamous epithelial cells: 1257.1" "Cancer enhanced" "Detected in many" "cervical cancer: 150.9;head and neck cancer: 196.3" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 21.5;hTCEpi: 8.6;RPMI-8226: 6.0" "Not detected" "Not detected" "CAB010070, HPA044999" Approved NA NA 1200000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB010070: , HPA044999: AB_2679177" "unprognostic (1.02e-3)" "unprognostic (1.18e-2)" "unprognostic (4.33e-2)" "unprognostic (1.37e-1)" "unprognostic (1.29e-2)" "unprognostic (2.16e-1)" "unprognostic (2.93e-1)" "unprognostic (3.11e-1)" "unprognostic (1.02e-2)" "unprognostic (9.64e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.71e-1)" "unprognostic (2.56e-1)" "unprognostic (1.65e-1)" "unprognostic (4.43e-3)" 0.5 0.1 0.2 0.0 0.2 0.0 5.4 1.5 0.1 107.9 0.0 0.1 0.0 0.1 0.1 507.1 1.2 0.0 0.1 0.0 0.3 17.3 1.6 0.0 0.0 0.5 0.3 0.1 0.2 0.0 0.3 0.0 0.2 2.9 0.0 0.0 121.0 0.1 1.0 179.0 0.2 0.0 0.0 0.1 0.3 1.7 0.7 79.5 0.1 0.0 39.8 0.2 200.8 0.0 21.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.5 0.1 0.0 0.3 0.5 0.3 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 28.4 29.8 6.3 157.1 2.2 13.3 22.4 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 5.9 0.0 4.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 28.5 0.0 1.4 8.3 0.3 0.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 6.5 0.0 59.6 0.7 0.3 0.0 0.0 0.9 6.7 0.1 1257.1 55.0 0.0 0.7 0.0 0.2 30.6 CAPNS2 "MGC12536, MGC14804" ENSG00000256812 "Calpain small subunit 2" Q96L46 16 55566684-55567687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 85.7;skin 1: 102.4" "Group enriched" "Detected in some" 7 "Basal keratinocytes: 87.8;Basal squamous epithelial cells: 117.3;Squamous epithelial cells: 108.6;Suprabasal keratinocytes: 149.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.3;urothelial cancer: 21.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.8;intermediate monocyte: 1.0" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 1.0" "Cell line enriched" "Detected in some" 10 "hTCEpi: 223.0" "Not detected" "Not detected" "HPA059749, HPA076768" Enhanced Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA059749: AB_2732639, HPA076768: AB_2732322" "unprognostic (3.26e-2)" "unprognostic (6.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.77e-3)" "unprognostic (4.14e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (7.21e-2)" "unprognostic (3.38e-2)" "unprognostic (3.62e-1)" "unprognostic (2.42e-2)" "unprognostic (4.48e-1)" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" 0.4 0.0 0.4 0.1 0.7 0.6 6.6 0.9 0.5 14.3 0.4 0.0 0.0 0.1 0.2 85.7 0.8 0.0 0.1 0.5 0.6 0.0 0.1 0.2 0.0 1.5 0.9 0.1 0.1 0.0 0.1 0.3 1.6 4.2 0.0 0.1 16.8 0.1 0.7 102.4 0.1 0.0 1.1 0.1 0.1 0.0 1.1 0.2 0.3 0.0 18.6 18.1 33.5 1.5 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 23.0 0.0 1.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.7 0.8 0.0 223.0 0.0 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 1.1 0.1 7.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 1.2 0.0 0.1 3.8 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.7 0.9 0.5 0.5 0.6 1.5 0.9 1.6 1.1 1.1 1.5 0.6 0.0 0.5 0.0 0.0 87.8 10.0 13.7 117.3 0.0 0.2 0.3 0.0 0.0 11.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.8 7.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.5 0.7 0.0 0.0 108.6 149.3 2.3 0.2 0.1 0.0 15.4 CBR3 SDR21C2 ENSG00000159231 "Carbonyl reductase 3" O75828 21 36135079-36146562 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.3;salivary gland: 41.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 102.5;Basal squamous epithelial cells: 107.0;Peritubular cells: 75.6;Squamous epithelial cells: 230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "B-cells: 23.9;NK-cells: 11.5;T-cells: 33.7" "Cell line enhanced" "Detected in many" "RPMI-8226: 64.9" "Region enhanced" "Detected in all" "basal ganglia: 48.6" "Low region specificity" "Detected in many" HPA018434 Uncertain Supported Nucleoplasm,Cytosol Yes NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA018434: AB_1846110" "unprognostic (3.64e-3)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.22e-2)" "unprognostic (6.12e-2)" "unprognostic (2.98e-2)" "unprognostic (3.75e-1)" "unprognostic (9.10e-2)" "prognostic unfavorable (5.95e-6)" "unprognostic (3.13e-1)" "unprognostic (1.80e-1)" "unprognostic (3.99e-3)" "unprognostic (1.94e-1)" 17.3 2.3 12.8 4.0 14.7 1.4 15.3 13.9 19.8 12.4 11.2 7.8 3.0 7.5 11.0 56.3 8.8 6.5 6.1 13.2 12.4 2.7 0.8 4.6 2.9 12.8 12.1 11.2 1.6 0.6 2.4 2.9 12.3 9.9 3.6 0.6 41.4 5.1 3.1 21.6 5.4 6.1 12.0 3.1 5.2 3.1 12.2 2.0 4.6 7.8 7.6 11.6 16.8 12.4 33.5 9.5 4.0 8.2 31.0 47.8 5.9 35.4 42.4 40.6 32.1 0.4 6.9 0.0 10.2 37.2 13.7 15.0 5.5 7.2 16.2 45.3 17.2 1.4 10.0 0.3 2.6 0.1 0.1 6.8 0.8 28.1 3.6 19.1 24.9 3.7 0.0 0.3 12.1 25.4 3.1 14.7 3.2 10.3 41.5 6.7 7.6 64.9 13.7 14.2 2.1 2.9 27.3 32.6 53.3 2.2 9.8 3.9 17.1 25.7 2.2 28.8 35.0 1.5 0.6 0.0 26.9 0.9 47.3 0.0 0.6 0.1 2.2 0.5 3.0 23.6 25.1 7.7 2.4 23.9 33.7 23.5 0.9 11.5 1.0 0.7 10.9 11.5 12.8 14.7 13.9 19.8 13.2 12.4 12.8 12.1 12.3 12.0 12.2 12.4 41.7 0.0 3.2 6.8 5.2 71.0 22.1 102.5 107.0 0.8 23.1 38.6 0.2 2.8 23.0 0.0 0.0 1.2 2.9 1.9 9.8 4.7 0.7 13.1 7.5 26.5 0.0 1.7 3.9 0.7 0.3 53.4 7.7 14.7 5.7 1.1 14.3 0.3 8.4 0.0 5.5 12.6 69.2 3.8 41.3 4.0 67.7 5.8 65.8 2.8 20.9 1.9 0.0 1.5 0.5 2.6 1.7 75.6 1.4 43.4 1.3 0.2 13.1 0.6 0.0 21.4 19.7 0.4 0.2 230.4 46.7 0.3 7.0 1.0 8.1 21.1 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823052-64844653 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 14.8;Gastric mucus-secreting cells: 23.0;Paneth cells: 18.3;Squamous epithelial cells: 19.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.3;HaCaT: 22.5;MCF7: 30.7;RT4: 18.4;SK-BR-3: 18.4;T-47d: 18.1" "Region enriched" "Detected in all" 4 "cerebellum: 10.5" "Low region specificity" "Detected in some" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 4.9 0.2 1.4 0.3 2.1 4.8 9.7 1.2 5.4 5.5 8.8 10.6 0.4 2.0 26.5 3.8 2.8 0.4 0.4 0.3 7.7 0.9 7.8 1.3 0.4 0.7 2.2 14.1 6.4 11.0 4.2 1.0 8.5 4.5 0.3 17.7 3.7 0.2 33.7 9.3 0.2 0.3 1.8 12.2 3.3 0.3 2.4 6.0 0.0 2.0 5.8 13.0 0.3 8.9 1.2 0.8 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 11.7 7.5 0.1 4.3 0.0 0.4 22.5 1.3 8.8 0.0 0.4 3.6 0.7 5.3 3.8 0.0 0.3 2.2 0.0 10.9 0.1 0.1 0.1 0.1 3.5 6.1 0.1 0.0 30.7 0.2 1.7 2.7 8.3 1.3 1.3 0.5 4.3 5.5 18.4 15.6 0.7 2.8 18.4 0.5 4.3 18.1 0.4 0.1 0.0 3.1 0.1 0.1 2.1 2.2 2.2 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 9.7 1.2 0.4 0.3 0.4 0.7 1.0 0.3 0.3 0.3 1.0 9.6 7.9 0.0 1.2 6.5 2.3 3.6 9.6 0.0 5.1 5.8 1.8 2.8 9.6 1.8 0.0 6.4 1.7 14.8 0.0 2.4 0.6 13.2 0.7 0.4 3.6 0.8 0.1 6.2 4.9 0.7 23.0 7.9 1.3 0.4 0.0 0.0 1.0 0.0 0.1 4.8 2.0 0.0 0.4 0.8 0.0 1.3 0.0 0.0 1.2 0.8 1.0 0.0 0.1 2.9 18.3 0.0 0.1 1.6 12.4 0.5 9.5 0.0 0.0 2.2 0.8 1.7 1.3 19.3 8.1 6.7 1.4 0.6 5.7 3.4 CERS3 "LASS3, MGC27091" ENSG00000154227 "Ceramide synthase 3" Q8IU89 15 100400395-100544995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 55.1;skin 1: 64.0;vagina: 30.3" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 18.9;Basal squamous epithelial cells: 39.3;Early spermatids: 23.5;Late spermatids: 17.5;Spermatocytes: 28.2;Squamous epithelial cells: 48.3;Suprabasal keratinocytes: 50.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 14.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTCEpi: 65.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006092, HPA024356" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA006092: AB_1079236, HPA024356: AB_1852721" "unprognostic (5.01e-3)" "unprognostic (3.43e-2)" "unprognostic (6.47e-4)" "unprognostic (2.35e-2)" "unprognostic (5.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.84e-3)" "unprognostic (3.23e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-5)" "unprognostic (2.65e-1)" "unprognostic (4.74e-4)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" 0.1 0.0 0.1 0.0 0.2 0.2 3.3 0.3 0.2 15.1 0.0 0.0 0.0 0.0 0.5 55.1 0.7 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.6 0.0 0.1 8.4 0.1 0.6 64.0 0.1 0.0 0.0 0.1 0.1 18.3 0.2 0.4 0.1 0.0 16.0 0.3 30.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 1.3 0.0 18.9 5.0 3.9 39.3 0.4 0.1 0.3 0.5 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.5 0.2 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.1 17.5 0.6 0.1 0.0 0.0 0.0 0.2 0.0 2.0 1.4 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 28.2 0.7 48.3 50.2 0.0 0.1 0.0 0.0 6.0 CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 117.5;skin 1: 88.7;vagina: 53.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 47.4;Basal respiratory cells: 57.5;Basal squamous epithelial cells: 39.9;Club cells: 37.1;Early spermatids: 30.2;Squamous epithelial cells: 167.1;Suprabasal keratinocytes: 54.8;Urothelial cells: 52.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "hTCEpi: 210.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 96000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" 0.8 0.1 0.2 0.1 0.6 0.0 4.6 0.4 0.5 22.8 0.1 0.6 0.2 0.0 0.5 117.5 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.7 0.4 2.4 0.7 0.0 13.2 0.2 0.2 88.7 0.8 0.0 0.4 0.0 0.1 0.6 0.3 1.0 0.0 0.0 26.0 21.2 53.1 1.0 0.0 0.0 0.0 0.0 0.6 3.0 38.9 1.7 2.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 0.0 33.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 210.8 1.0 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.9 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.5 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.7 0.0 47.4 13.1 57.5 39.9 0.0 7.7 2.8 0.4 0.0 37.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.3 4.1 0.0 3.1 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 2.5 2.1 0.3 0.0 8.0 0.0 0.0 0.0 0.6 0.2 0.0 167.1 54.8 0.1 0.5 0.0 0.1 52.9 CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 952.0;esophagus: 3093.3;vagina: 1442.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 57.9;Breast myoepithelial cells: 51.6;Squamous epithelial cells: 71.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 367.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 61.2;naive B-cell: 70.2" "Lineage enriched" "Detected in many" 12 "B-cells: 70.2" "Cell line enhanced" "Detected in many" "A549: 18.1;HEK 293: 25.7;MCF7: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge" "HPA049073: AB_2680620, HPA053997: AB_2682337" "unprognostic (5.08e-2)" "unprognostic (4.21e-3)" "unprognostic (2.52e-1)" "unprognostic (7.22e-2)" "unprognostic (3.15e-2)" "unprognostic (8.35e-3)" "unprognostic (6.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.52e-1)" "unprognostic (9.44e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (7.77e-3)" "prognostic favorable (4.02e-5)" "unprognostic (2.45e-1)" 4.3 5.3 1.8 0.4 4.2 0.6 12.9 1.9 2.2 952.0 1.3 3.2 0.4 1.5 7.3 3093.3 1.6 0.1 1.9 1.9 2.8 2.3 1.4 0.9 0.7 2.1 1.9 1.0 3.3 1.6 2.2 0.1 1.7 8.6 1.3 0.1 661.6 1.1 1.7 555.6 3.5 0.5 1.7 3.3 3.3 2.4 2.9 2.8 1.8 0.0 276.8 2.4 1442.7 1.6 6.0 18.1 0.4 1.6 0.8 0.9 0.2 1.0 0.3 0.4 0.4 1.0 1.6 5.1 8.0 0.2 1.2 2.4 1.5 2.3 0.1 0.0 25.7 0.4 6.9 1.9 0.0 0.0 0.1 1.8 4.0 1.0 0.0 0.1 0.0 4.7 1.1 0.2 0.0 12.6 0.1 0.1 6.6 8.1 5.4 2.2 0.3 2.9 1.6 2.3 2.7 7.7 3.4 5.1 2.5 2.7 6.2 2.6 0.0 0.0 5.3 0.2 0.1 5.8 7.6 3.6 0.1 2.2 0.3 0.1 4.6 0.1 1.7 3.9 0.4 61.2 1.3 1.2 5.9 70.2 0.6 0.9 1.3 0.0 0.9 1.3 0.1 2.2 1.8 4.2 1.9 2.2 1.9 2.8 2.1 1.9 1.7 1.7 2.9 1.6 32.7 3.2 2.2 0.0 24.6 4.6 16.8 28.5 14.8 0.1 57.9 51.6 0.8 2.8 20.2 33.1 0.0 0.2 2.1 24.5 7.9 13.1 1.5 20.6 3.9 9.3 32.5 3.6 0.1 2.5 0.3 2.3 4.6 23.9 4.5 7.2 3.9 0.7 5.7 0.0 0.2 33.4 14.2 3.8 7.7 3.9 5.3 6.3 3.6 0.0 6.4 0.3 7.2 0.0 0.1 2.4 39.4 4.5 0.5 11.5 43.8 12.3 10.5 0.1 0.0 0.9 8.0 0.4 17.4 71.8 12.9 0.3 1.3 1.1 41.8 27.0 CRABP2 CRABP-II ENSG00000143320 "Cellular retinoic acid binding protein 2" P29373 1 156699606-156705816 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1189.7;vagina: 604.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 485.4;Breast glandular cells: 224.2;Club cells: 266.7;Squamous epithelial cells: 714.0;Urothelial cells: 506.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1592.5;MCF7: 625.9;T-47d: 1201.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 36.0" HPA004135 Supported Supported Nucleoplasm,Cytosol NA NA 76000 "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA004135: AB_1846516" "unprognostic (1.17e-2)" "unprognostic (9.30e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (1.75e-2)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" "unprognostic (6.45e-2)" "unprognostic (7.79e-2)" "unprognostic (7.23e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.19e-13)" "unprognostic (3.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" 22.2 8.0 9.6 4.8 11.5 5.7 104.5 10.5 18.8 273.7 29.4 13.3 0.9 76.3 4.7 1189.7 83.1 18.2 5.5 10.7 12.8 12.0 2.3 6.4 3.9 8.0 8.2 6.2 3.4 55.1 43.5 40.5 7.8 34.8 4.8 4.5 93.5 57.1 5.0 179.0 3.9 57.0 7.4 7.9 5.6 5.3 12.0 15.5 14.5 1.8 76.2 81.2 604.9 10.1 103.4 5.4 115.3 1.6 147.1 218.0 0.4 215.4 1592.5 17.3 21.3 184.9 369.8 1.6 103.1 234.0 2.2 131.2 28.1 0.8 5.1 2.9 8.1 0.1 13.5 1.6 29.0 0.3 2.5 69.3 10.6 25.4 0.5 13.8 0.7 2.0 1.0 2.2 1.9 625.9 1.7 1.9 136.5 12.3 57.3 1.7 0.8 3.4 2.3 4.0 280.7 20.2 3.0 366.2 1.5 214.9 1201.3 0.7 0.2 4.2 63.1 35.5 13.4 9.8 23.8 1.3 28.6 1.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.5 10.5 18.8 10.7 12.8 8.0 8.2 7.8 7.4 12.0 10.1 7.0 0.0 2.6 1.3 1.8 65.0 131.2 485.4 104.2 1.8 224.2 96.8 0.7 1.5 266.7 16.5 2.1 53.9 4.9 0.9 0.0 12.6 2.2 18.0 51.9 10.3 0.0 0.0 3.1 5.2 6.2 168.4 1.1 29.3 0.0 0.5 6.4 0.2 10.0 0.0 1.8 0.9 40.7 0.0 55.4 1.0 19.9 3.9 62.2 0.0 0.0 1.0 0.0 1.5 0.3 18.1 0.2 37.6 0.2 194.9 0.1 0.3 28.2 0.6 0.0 4.3 40.0 2.0 6.1 714.0 190.7 18.1 7.6 4.8 1.7 506.4 CRNN "C1orf10, SEP53" ENSG00000143536 Cornulin Q9UBG3 1 152409243-152414263 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5346.2;vagina: 1691.7" "Cell type enriched" "Detected in some" 24 "Squamous epithelial cells: 79.9" "Group enriched" "Detected in many" 18 "cervical cancer: 19.3;head and neck cancer: 74.0;stomach cancer: 22.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024343, CAB026182" Enhanced NA NA 100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB026182: , HPA024343: AB_1847162" "unprognostic (1.96e-2)" "unprognostic (1.74e-6)" "unprognostic (4.20e-2)" "unprognostic (3.43e-1)" "unprognostic (6.43e-3)" 1.0 0.9 0.1 0.0 0.1 0.0 0.7 0.0 0.2 865.3 0.0 0.6 0.0 0.8 0.0 5346.2 0.7 1.1 1.8 0.1 0.1 0.6 1.4 0.4 0.0 0.1 0.1 1.2 3.0 0.0 3.5 0.0 0.1 0.8 0.0 0.0 906.9 0.0 1.4 8.2 1.2 0.1 0.1 0.9 5.0 0.8 0.1 0.0 0.6 0.0 249.8 1.2 1691.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 79.9 0.0 0.0 0.0 0.0 0.0 0.0 CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5912.9;vagina: 1853.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2493.8;Club cells: 768.0;Kupffer cells: 579.4;monocytes: 1298.6;Squamous epithelial cells: 3020.6" "Cancer enhanced" "Detected in all" "cervical cancer: 227.7;head and neck cancer: 405.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "classical monocyte: 514.7;intermediate monocyte: 269.1;myeloid DC: 382.9;neutrophil: 245.6;non-classical monocyte: 161.7" "Group enriched" "Detected in all" 193 "dendritic cells: 382.9;granulocytes: 245.6;monocytes: 514.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 282.0;hTCEpi: 1218.6;THP-1: 789.0;U-698: 504.5;U-937: 250.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 28000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: AB_1078610" "unprognostic (5.22e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.07e-2)" "unprognostic (7.79e-3)" "prognostic favorable (5.86e-4)" "unprognostic (4.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (8.89e-2)" "unprognostic (3.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.99e-1)" 30.7 4.7 0.8 27.1 0.9 297.8 56.3 1.0 3.7 961.0 1.4 3.8 1.1 2.2 10.3 5912.9 4.6 7.2 5.9 0.8 1.0 2.4 38.9 26.0 25.1 1.5 0.9 21.1 3.7 0.8 5.0 19.0 1.3 19.7 3.6 0.3 996.1 9.6 4.6 369.1 5.8 6.3 1.1 20.4 30.3 1.3 1.4 46.5 2.7 2.8 941.0 39.1 1853.3 1.6 14.6 1.3 0.2 3.2 31.5 58.0 2.9 0.6 0.8 0.0 0.0 0.0 0.0 3.2 7.6 5.9 0.5 86.9 0.0 282.0 0.0 0.3 0.2 0.7 0.0 6.8 6.8 117.6 1.9 30.5 1218.6 2.9 119.1 0.0 0.0 1.5 0.8 29.9 0.5 0.8 0.2 108.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 141.3 0.0 0.0 14.1 7.5 10.4 0.1 1.6 789.0 0.5 1.7 19.7 0.2 0.9 0.0 1.7 504.5 26.4 250.3 0.3 8.8 514.7 16.4 0.6 269.1 1.5 1.5 0.7 0.6 382.9 0.5 0.5 0.7 245.6 1.9 161.7 6.9 1.0 283.2 0.8 0.9 1.0 3.7 0.8 1.0 1.5 0.9 1.3 1.1 1.4 1.6 1.1 6.4 19.8 0.0 5.0 83.5 136.5 2493.8 117.8 0.0 7.1 119.8 0.2 2.8 768.0 0.0 0.0 230.6 7.4 3.9 0.0 2.1 0.4 0.3 0.4 3.0 0.0 3.8 0.1 22.1 17.8 13.6 12.8 0.3 13.9 0.1 6.1 96.0 134.5 0.0 0.1 0.5 179.0 579.4 90.6 2.4 10.2 243.7 8.8 0.0 1298.6 0.0 20.6 0.5 0.2 46.2 1.5 3.8 2.8 30.2 0.0 0.7 115.7 0.0 32.9 8.8 24.3 0.1 0.5 3020.6 205.0 334.2 4.9 26.1 2.0 134.1 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 DAPL1 ENSG00000163331 "Death associated protein like 1" A0PJW8 2 158795317-158862781 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 196.9;esophagus: 242.0;skin 1: 301.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 212.9;Muller glia cells: 913.0;Squamous epithelial cells: 736.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 4.0;hTCEpi: 23.2;SCLC-21H: 5.9;U-87 MG: 8.4" "HPA046937, HPA058635" Enhanced Approved "Nucleoplasm,Nuclear bodies,Microtubules" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies, Microtubules" "HPA046937: AB_2679870, HPA058635: AB_2732625" "unprognostic (3.95e-5)" "prognostic favorable (8.43e-4)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (4.63e-2)" "unprognostic (8.59e-2)" "unprognostic (5.24e-2)" "unprognostic (4.59e-2)" "unprognostic (2.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-3)" "unprognostic (4.09e-2)" "unprognostic (6.68e-2)" "unprognostic (3.00e-2)" "unprognostic (2.30e-3)" 1.9 56.0 1.6 0.1 1.8 0.8 28.7 1.6 6.6 47.6 1.2 2.9 0.5 0.6 196.9 242.0 80.5 0.6 0.5 1.3 9.3 3.6 0.2 1.6 0.6 1.5 5.3 1.0 22.8 0.0 24.4 0.1 2.4 9.2 0.7 115.6 30.2 1.1 1.0 301.0 1.0 0.5 1.3 0.3 1.5 1.5 4.3 4.8 34.3 0.0 25.0 8.6 108.1 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.0 0.1 0.2 23.2 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.4 5.9 0.0 0.0 0.0 0.6 0.0 0.7 1.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 8.4 0.0 0.0 1.2 0.8 0.5 0.1 0.6 0.2 0.4 0.2 0.1 0.3 0.4 0.1 0.1 0.5 0.7 0.1 1.2 0.4 0.1 1.6 1.8 1.6 6.6 1.3 9.3 1.5 5.3 2.4 1.3 4.3 1.2 0.6 0.0 0.0 0.0 4.1 106.9 51.8 74.8 212.9 7.2 15.0 19.6 0.1 2.8 29.8 9.2 6.2 6.0 4.9 2.0 3.9 7.6 13.8 5.6 2.2 2.0 3.0 0.0 0.2 6.0 12.8 2.4 0.0 5.4 4.5 148.1 0.7 14.3 14.7 3.3 0.4 2.0 14.2 9.1 9.3 56.1 4.1 5.0 12.4 0.0 5.4 913.0 2.1 1.0 0.1 5.8 7.1 2.2 3.4 11.8 5.9 13.3 4.8 23.8 0.0 1.9 10.9 10.8 4.2 736.5 126.6 4.5 3.1 1.7 2.3 67.4 DMRTA1 ENSG00000176399 "DMRT like family A1" Q5VZB9 9 22446824-22455740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 8.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.4;Distal tubular cells: 15.6;Glandular and luminal cells: 14.5;Hepatocytes: 30.8;Proximal tubular cells: 29.2;Squamous epithelial cells: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.3;hTERT-RPE1: 7.4;LHCN-M2: 2.9;RPTEC TERT1: 3.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.2" "HPA044764, HPA062253" Uncertain Approved Vesicles NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA044764: AB_10959788, HPA062253: AB_2684726" "unprognostic (1.47e-1)" "unprognostic (2.48e-2)" "unprognostic (2.86e-1)" "unprognostic (7.74e-4)" "unprognostic (3.81e-2)" "unprognostic (2.67e-3)" "unprognostic (4.36e-2)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (9.64e-2)" "unprognostic (3.65e-3)" "unprognostic (2.92e-1)" "prognostic favorable (1.14e-6)" "unprognostic (8.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (8.53e-3)" 1.8 0.0 0.4 0.2 0.4 0.0 0.4 0.3 0.3 1.6 2.4 0.4 0.6 0.3 1.2 1.7 0.3 0.9 0.3 0.6 0.3 3.4 8.4 0.9 0.4 0.4 1.6 0.2 1.4 2.2 0.7 0.0 0.4 1.4 0.3 0.1 3.5 0.4 0.7 0.2 0.5 0.1 0.4 0.2 2.0 0.1 0.7 0.5 1.8 1.1 0.8 0.4 0.1 0.4 0.2 0.3 0.0 0.0 0.2 0.1 0.1 0.0 6.3 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.2 1.2 1.7 0.2 0.0 0.4 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.1 7.4 0.4 0.0 0.0 2.3 2.9 0.6 0.0 0.0 1.2 0.3 2.1 0.0 0.1 0.9 3.0 0.0 0.1 0.0 0.8 0.5 1.4 1.4 0.0 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.3 0.6 0.3 0.4 1.6 0.4 0.4 0.7 0.4 0.1 0.0 2.7 2.0 0.1 0.0 4.8 7.2 19.4 0.5 1.9 1.0 1.9 5.7 5.6 5.5 0.0 0.0 0.0 1.1 15.6 6.9 0.1 10.7 1.4 0.3 2.4 0.0 0.0 6.7 0.0 0.8 10.2 14.5 0.0 0.6 0.0 30.8 0.3 0.0 0.0 0.7 8.2 0.3 0.3 0.1 0.3 0.4 0.0 1.0 0.0 5.4 0.0 0.0 0.0 7.8 0.2 0.0 0.1 6.3 4.1 29.2 5.9 0.1 0.0 2.9 0.6 0.2 1.2 26.5 0.4 0.1 0.3 0.0 1.9 8.2 DMRTA2 ENSG00000142700 "DMRT like family A2" Q96SC8 1 50417550-50423443 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.6;esophagus: 1.5;pituitary gland: 2.0;testis: 1.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.9;Basal squamous epithelial cells: 17.6;Early spermatids: 10.8;Squamous epithelial cells: 5.9" "Cancer enhanced" "Detected in many" "glioma: 5.3" "Region enhanced" "Detected in single" "white matter: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;HBEC3-KT: 3.3;RH-30: 11.7;SH-SY5Y: 2.4;SiHa: 2.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA043098, HPA062958" Uncertain Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria Nucleoplasm "HPA043098: AB_10796684, HPA062958: AB_2684911" "unprognostic (1.60e-1)" "unprognostic (4.56e-3)" "unprognostic (2.62e-1)" "unprognostic (3.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.75e-2)" "unprognostic (1.15e-2)" "unprognostic (3.29e-1)" "unprognostic (6.89e-2)" "unprognostic (4.79e-1)" "unprognostic (7.47e-2)" "unprognostic (1.21e-3)" "unprognostic (7.08e-3)" "unprognostic (4.16e-2)" "unprognostic (7.85e-2)" "unprognostic (2.68e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.4 0.4 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 1.4 0.0 0.9 3.3 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 2.4 2.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.4 0.3 0.2 0.6 0.5 0.3 0.2 0.8 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 17.6 0.0 0.1 0.0 1.3 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 10.8 0.1 0.1 0.1 1.2 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.2 1.3 1.0 5.9 0.0 0.0 0.0 0.0 0.1 0.0 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 99.2;skin 1: 372.6" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 500.7;Basal squamous epithelial cells: 214.5;Squamous epithelial cells: 419.6;Suprabasal keratinocytes: 688.8" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 246.2;HBEC3-KT: 54.6;hTCEpi: 156.7;hTERT-HME1: 103.6;REH: 44.8" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" 4.8 0.1 0.1 0.5 0.0 0.2 12.5 0.1 0.0 23.8 0.0 0.3 0.4 0.1 1.2 99.2 1.3 0.0 0.4 0.1 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.4 0.2 3.4 0.2 12.5 0.0 6.0 0.1 0.1 19.6 1.3 1.0 372.6 0.3 0.5 0.0 0.0 0.1 0.1 0.0 7.7 0.1 0.0 24.7 3.5 48.5 0.0 17.2 1.8 0.2 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 246.2 0.0 54.6 0.0 0.1 14.6 0.9 4.7 0.4 9.7 0.1 0.2 10.2 156.7 0.0 103.6 19.6 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.9 0.1 21.8 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.1 0.3 0.0 500.7 62.0 49.5 214.5 0.0 3.1 8.0 1.3 0.0 30.3 0.0 0.0 73.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.3 2.4 0.0 0.3 0.0 14.2 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.3 0.0 0.3 0.2 12.2 0.0 34.8 0.0 0.0 0.6 39.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.2 32.1 0.0 0.1 10.2 0.0 0.0 0.0 3.4 0.1 0.1 419.6 688.8 25.0 2.3 0.0 0.1 89.1 DSG3 CDHF6 ENSG00000134757 "Desmoglein 3" P32926 18 31447741-31478702 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 313.9;vagina: 119.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 197.6;Basal squamous epithelial cells: 101.9;Squamous epithelial cells: 470.6;Suprabasal keratinocytes: 206.4;Urothelial cells: 87.2" "Cancer enhanced" "Detected in many" "cervical cancer: 104.0;head and neck cancer: 183.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 53 "basophil: 8.2" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.2" "Group enriched" "Detected in some" 7 "HaCaT: 204.4;hTCEpi: 494.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046864, HPA056863, CAB069880" Enhanced NA NA 190000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB069880: AB_2093604, HPA046864: AB_2679846, HPA056863: AB_2683260" "unprognostic (5.76e-3)" "unprognostic (6.99e-2)" "unprognostic (7.67e-2)" "unprognostic (7.79e-2)" "unprognostic (1.00e-2)" "unprognostic (4.08e-3)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (1.43e-5)" "unprognostic (8.26e-2)" "unprognostic (8.35e-7)" "unprognostic (8.85e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.90e-4)" 0.3 0.0 0.1 0.2 0.1 0.2 3.9 0.1 0.2 71.1 0.1 0.0 5.4 0.0 0.0 313.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.2 0.4 0.1 0.0 43.6 0.0 0.1 39.9 3.9 0.0 0.0 0.0 0.2 0.1 0.2 14.8 0.0 0.0 72.7 1.2 119.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 204.4 0.0 46.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 494.7 0.0 49.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.2 28.9 18.5 0.0 0.2 197.6 17.4 32.2 101.9 0.3 0.5 5.0 0.3 0.0 21.1 0.0 0.0 0.4 1.5 0.2 0.0 0.2 0.6 0.1 0.3 2.7 0.0 0.0 2.7 0.4 0.4 2.2 0.0 0.1 12.6 0.0 0.4 0.3 0.4 0.0 0.1 1.3 2.0 0.3 7.7 0.5 0.0 3.2 7.2 0.0 0.7 0.1 0.0 0.0 0.1 1.3 2.5 0.7 1.2 12.3 7.1 0.1 15.9 0.8 6.6 0.0 1.8 3.3 2.8 470.6 206.4 0.3 1.3 0.0 6.5 87.2 DSG4 "CDHF13, LAH" ENSG00000175065 "Desmoglein 4" Q86SJ6 18 31376777-31414912 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skin 1: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Squamous epithelial cells: 1.0;Urothelial cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 133 "HaCaT: 37.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059456, HPA079244" Enhanced NA NA 320000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA059456: AB_2684025, HPA079244: " "unprognostic (9.86e-2)" "unprognostic (8.61e-2)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "unprognostic (5.55e-2)" "unprognostic (5.61e-2)" "unprognostic (2.11e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-1)" "unprognostic (2.58e-1)" "unprognostic (2.14e-1)" "unprognostic (1.79e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.0 0.0 0.0 0.0 0.0 0.2 1.3 DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 902.0;Cardiomyocytes: 729.7;Squamous epithelial cells: 1657.5;Suprabasal keratinocytes: 2018.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 278.0;HaCaT: 302.6;HBEC3-KT: 217.5;hTCEpi: 666.3;SuSa: 204.1" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" 5.2 11.6 4.2 7.0 1.8 0.6 65.8 2.5 3.5 151.0 19.3 46.0 52.0 5.4 27.5 460.7 16.3 7.8 84.9 3.4 0.9 22.4 41.9 6.1 3.7 1.6 2.0 2.0 111.5 54.9 9.0 63.3 1.5 29.9 43.5 21.2 125.1 11.7 3.4 854.8 42.3 2.9 2.4 3.2 48.1 1.5 2.2 37.1 41.5 0.6 78.7 13.1 286.1 0.9 132.2 38.9 0.0 0.1 5.6 8.2 278.0 25.5 21.8 12.4 12.0 110.8 33.5 0.1 35.8 40.9 10.0 302.6 46.1 217.5 2.2 0.1 54.1 0.0 21.5 149.5 0.0 0.6 0.9 1.9 666.3 11.0 121.7 30.0 0.0 0.6 0.2 0.2 22.0 61.4 0.1 1.0 5.6 62.6 19.6 0.1 0.1 32.9 45.3 34.8 12.6 0.3 28.5 59.9 0.2 204.1 71.0 0.3 0.0 4.8 1.2 0.3 0.3 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.8 2.5 3.5 3.4 0.9 1.6 2.0 1.5 2.4 2.2 0.9 7.6 51.3 17.0 0.0 7.5 902.0 164.5 157.3 278.3 4.4 184.5 126.4 729.7 97.2 197.5 60.7 14.6 273.0 1.2 357.1 1.9 160.6 1.8 306.5 42.4 46.9 174.6 0.0 0.1 111.9 273.1 51.2 237.0 560.1 3.8 532.2 4.6 186.6 27.5 0.0 0.9 204.7 111.9 1.9 77.8 1.3 0.9 5.9 101.4 3.7 2.6 14.7 0.0 0.0 0.1 167.4 284.2 0.0 5.7 204.0 180.7 12.0 176.6 28.6 0.0 0.4 67.4 1.3 2.7 1657.5 2018.0 385.7 8.1 0.3 247.8 269.9 DYNAP "C18orf26, FLJ39106" ENSG00000178690 "Dynactin associated protein" Q8N1N2 18 54587757-54599493 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "esophagus: 29.3" "Cell type enriched" "Detected in single" 4 "Squamous epithelial cells: 1.7" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA011148 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA011148: AB_1845609" "unprognostic (9.88e-2)" "unprognostic (2.51e-2)" "unprognostic (1.75e-3)" "unprognostic (1.45e-1)" "unprognostic (8.09e-3)" 0.8 0.4 1.7 0.6 1.3 2.2 0.6 2.2 2.4 0.6 0.0 0.6 0.6 1.0 2.1 29.3 0.5 0.6 1.0 1.4 1.8 0.9 0.8 0.5 1.1 0.9 0.4 0.8 0.4 0.3 0.0 0.4 1.2 0.3 0.7 2.6 1.9 0.5 0.8 1.1 0.5 0.8 0.1 2.4 0.4 1.0 1.5 0.3 0.5 0.4 1.9 0.3 0.2 2.4 0.5 0.2 1.3 0.6 0.6 1.4 1.3 0.3 0.5 1.0 1.0 0.7 0.5 0.7 0.5 0.6 1.1 0.5 0.9 0.0 0.5 0.2 0.2 0.2 0.9 0.4 0.5 0.7 0.6 0.6 0.1 0.9 0.3 0.3 0.2 0.6 1.0 12.9 0.1 0.2 0.5 0.4 2.0 0.2 0.3 0.5 1.5 0.6 0.3 0.7 0.5 0.7 0.2 0.3 2.4 0.9 0.4 0.8 2.2 0.4 2.4 0.5 0.4 0.5 0.4 1.0 0.6 0.3 0.3 0.3 0.3 0.6 0.2 0.3 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.8 0.2 0.8 0.2 0.0 0.0 1.7 1.3 2.2 2.4 1.4 1.8 0.9 0.4 1.2 0.1 1.5 2.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.7;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.2;Gastric mucus-secreting cells: 4.6;Proximal enterocytes: 6.5;Squamous epithelial cells: 21.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 10.5;naive B-cell: 15.9" "Lineage enriched" "Detected in many" 7 "B-cells: 15.9" "Cell line enhanced" "Detected in many" "Daudi: 73.8;OE19: 28.5;T-47d: 39.0;U-698: 149.9" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" 0.5 0.9 1.0 9.7 1.0 0.2 5.2 1.0 1.1 1.6 4.7 8.0 14.1 0.6 1.1 4.5 3.9 0.7 0.5 1.0 1.1 1.4 0.7 1.5 49.7 1.0 1.1 1.7 0.4 1.6 0.5 3.7 1.1 2.0 12.3 0.1 2.2 1.0 0.4 25.0 12.9 1.0 1.0 1.0 1.8 16.2 1.4 1.5 0.7 1.9 57.7 0.7 0.8 1.1 2.1 0.2 0.6 1.1 4.9 1.2 0.4 0.2 1.3 2.8 3.1 0.0 1.3 73.8 0.1 1.2 0.1 13.7 1.3 0.7 1.4 1.6 7.3 0.4 2.6 4.6 1.0 0.1 0.0 1.4 12.3 0.7 0.2 0.2 1.1 0.4 0.2 0.0 0.7 4.0 1.5 1.4 0.1 28.5 2.4 0.8 0.0 0.0 1.8 0.0 9.5 0.0 1.7 21.5 0.0 0.3 39.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 149.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 10.5 0.6 0.1 0.0 15.9 1.1 0.2 0.0 0.1 0.0 2.2 0.6 0.6 1.0 1.0 1.0 1.1 1.0 1.1 1.0 1.1 1.1 1.0 1.4 1.1 0.1 0.0 0.0 0.0 2.2 0.4 0.1 0.2 5.2 0.0 0.7 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.3 1.2 0.0 0.1 1.8 0.4 0.1 0.2 0.0 0.4 0.1 0.7 0.0 0.5 4.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.5 0.0 0.0 0.5 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 6.5 0.1 3.1 0.0 0.0 0.2 0.4 0.2 0.2 21.0 1.0 0.3 0.1 0.1 2.3 0.2 EML3 "ELP95, FLJ35827" ENSG00000149499 "EMAP like 3" Q32P44 11 62602218-62612775 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.08e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-1)" "unprognostic (1.02e-3)" "unprognostic (2.11e-1)" "unprognostic (4.56e-2)" "unprognostic (2.12e-2)" "unprognostic (1.34e-2)" "unprognostic (1.07e-1)" "unprognostic (5.36e-2)" "unprognostic (9.46e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.13e-8)" "unprognostic (1.42e-1)" "unprognostic (2.68e-2)" "unprognostic (3.80e-1)" "unprognostic (2.52e-1)" 38.6 21.6 15.3 28.3 15.4 21.5 35.3 13.5 15.1 36.7 13.5 21.0 10.5 29.4 7.8 49.6 31.5 14.5 20.6 14.5 14.9 32.0 31.2 29.0 26.9 19.6 15.8 36.4 22.2 13.4 15.6 12.3 17.5 28.1 9.3 17.4 24.3 13.2 10.1 32.4 26.4 14.7 14.8 44.1 24.5 12.8 18.7 18.7 27.1 4.3 22.6 27.1 32.0 18.9 18.8 13.3 13.9 12.7 19.8 33.8 12.5 17.4 18.7 18.6 11.4 11.3 29.8 33.2 43.3 24.4 14.0 29.8 12.3 31.9 9.6 43.5 12.1 31.1 36.9 9.5 27.4 22.8 26.1 46.5 13.3 15.3 22.9 36.0 37.9 14.5 23.7 32.6 24.9 52.1 16.0 28.2 3.4 22.4 18.5 21.1 12.8 71.2 21.5 21.0 5.4 18.7 12.9 44.0 22.1 12.8 43.9 15.5 42.6 24.3 20.0 19.2 19.6 45.3 27.9 20.8 26.4 15.4 17.8 8.7 4.5 5.7 4.6 4.9 4.6 3.1 4.4 4.8 3.4 3.8 3.9 4.8 2.7 5.6 4.6 2.4 5.5 4.4 15.3 15.4 13.5 15.1 14.5 14.9 19.6 15.8 17.5 14.8 18.7 18.9 29.8 6.4 14.5 15.3 18.5 14.3 12.1 14.5 30.1 7.7 13.9 18.3 4.8 15.7 11.6 11.0 8.4 19.6 14.0 12.5 5.9 9.3 7.4 5.9 8.3 27.0 10.2 11.6 0.3 13.6 15.2 12.8 19.9 7.6 3.8 8.1 37.5 18.5 15.1 1.7 1.1 11.0 12.2 23.2 8.5 26.8 22.4 16.7 5.4 6.5 16.1 6.6 23.7 5.0 4.5 20.1 11.5 18.0 15.9 10.3 9.5 5.5 7.6 22.6 19.7 8.0 12.8 7.3 12.3 74.1 21.6 16.8 23.5 10.2 10.3 14.1 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 57.2;parathyroid gland: 206.5" "Cell type enhanced" "Detected in many" "Early spermatids: 23.3;Gastric mucus-secreting cells: 13.3;Proximal enterocytes: 13.2;Squamous epithelial cells: 28.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "CACO-2: 17.9;HaCaT: 16.6;HBEC3-KT: 13.5;MCF7: 15.0;NTERA-2: 54.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" CAB026144 Uncertain NA NA 32000000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 5: NTERA-2 - Transcription" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.1 0.0 0.0 1.3 0.0 0.3 2.2 0.4 0.1 11.2 1.2 3.7 8.4 0.3 1.2 57.2 3.4 1.5 0.0 0.0 0.0 5.8 15.6 2.3 2.0 0.0 0.0 0.0 5.7 206.5 2.5 0.6 0.0 4.0 1.6 0.0 11.0 1.2 0.0 19.7 6.2 0.1 0.0 0.9 4.2 1.9 0.0 3.4 5.4 0.0 3.5 1.9 25.8 0.1 8.7 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 17.9 7.1 0.0 0.1 0.0 0.0 16.6 0.0 13.5 0.0 0.0 0.0 1.8 0.0 1.7 0.0 0.8 0.1 0.0 4.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 15.0 0.0 1.9 54.4 8.8 0.0 0.0 0.0 0.0 1.1 6.7 0.3 0.0 0.0 8.2 0.0 3.2 3.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.2 0.0 3.8 2.9 0.1 0.1 0.0 0.4 0.1 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.2 0.3 0.1 2.0 6.3 6.5 6.8 0.0 3.3 5.0 1.0 2.8 9.9 7.3 0.0 2.0 0.2 4.2 0.0 4.4 23.3 4.0 1.0 0.2 1.2 0.0 0.6 4.3 2.6 0.5 13.3 6.6 0.0 0.0 0.4 8.8 0.4 0.0 0.3 4.7 2.0 0.3 0.3 9.9 0.6 0.3 0.0 1.0 0.0 0.3 0.0 0.5 0.2 6.3 8.8 0.0 0.6 2.0 13.2 1.5 2.1 0.2 0.0 0.4 0.4 0.5 1.9 28.7 3.7 1.0 4.4 0.0 7.6 5.5 EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 68.9;skin 1: 76.5;vagina: 36.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.5;Club cells: 19.3;Squamous epithelial cells: 30.7;Suprabasal keratinocytes: 43.3;Urothelial cells: 23.3" "Cancer enhanced" "Detected in many" "cervical cancer: 30.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 19 "dendritic cells: 1.3;monocytes: 2.4" "Cell line enhanced" "Detected in some" "EFO-21: 2.5;NTERA-2: 2.3;OE19: 8.4;SuSa: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA012842: AB_10601648" "unprognostic (1.39e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "prognostic favorable (2.27e-5)" "unprognostic (8.83e-3)" "unprognostic (1.50e-1)" "unprognostic (3.90e-1)" "unprognostic (4.36e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" 0.5 0.3 0.8 0.2 0.8 0.2 1.5 0.6 0.9 14.7 0.7 0.2 0.2 0.4 0.3 68.9 1.7 1.3 0.5 0.7 0.9 3.3 0.3 1.7 0.1 0.9 0.8 0.7 0.2 3.0 1.8 0.4 0.8 1.5 0.2 0.2 7.6 0.9 0.4 76.5 0.3 0.4 0.8 2.6 0.8 2.1 0.9 1.7 0.4 0.1 26.7 8.6 36.6 0.8 0.1 0.2 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 2.5 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.3 2.3 8.4 0.3 0.0 0.0 0.0 0.0 0.5 1.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 1.3 0.0 0.2 0.8 0.8 0.6 0.9 0.7 0.9 0.9 0.8 0.8 0.8 0.9 0.8 0.2 0.0 1.1 0.0 0.2 7.0 2.6 15.5 0.0 0.4 0.9 0.6 0.5 5.7 19.3 5.5 0.0 1.6 0.0 0.1 1.9 0.5 0.2 0.7 0.4 0.6 0.0 0.0 0.1 0.0 3.4 0.6 0.0 1.7 0.0 0.4 1.1 0.0 0.6 0.0 0.1 0.1 2.0 3.2 1.4 0.0 0.0 1.5 0.0 0.0 0.6 2.5 0.0 0.0 0.1 0.6 0.0 0.0 0.0 2.6 0.2 0.0 3.3 0.0 0.0 0.8 2.5 4.6 2.1 30.7 43.3 2.6 0.2 0.2 0.1 23.3 EVPL EVPK ENSG00000167880 Envoplakin Q92817 17 76004502-76027306 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 281.2;skin 1: 147.4;vagina: 101.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.7;Squamous epithelial cells: 94.1;Suprabasal keratinocytes: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 59.8;MCF7: 40.4;RT4: 87.8;SK-BR-3: 43.2;T-47d: 54.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002220, HPA053969" Enhanced Supported "Intermediate filaments,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Cytosol "CAB002220: AB_563701, HPA053969: AB_2682326" "unprognostic (2.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (4.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-2)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-1)" "unprognostic (7.40e-3)" "unprognostic (2.64e-1)" "unprognostic (2.40e-2)" "unprognostic (2.31e-1)" "unprognostic (3.47e-1)" "unprognostic (7.93e-2)" "unprognostic (3.09e-2)" 1.3 0.3 0.6 1.0 0.6 2.5 2.6 1.1 1.0 47.5 0.8 8.9 11.0 1.5 1.7 281.2 2.1 1.7 0.2 0.6 0.3 17.0 0.3 9.4 0.6 2.8 1.3 0.3 4.0 3.4 1.5 0.3 2.8 8.0 1.5 0.6 42.3 1.8 1.4 147.4 9.1 1.0 0.5 0.3 5.2 0.8 0.6 0.4 10.7 0.1 7.9 12.7 101.9 1.5 28.1 23.4 0.0 0.3 0.2 0.0 9.6 0.2 0.0 0.0 0.0 2.6 16.7 0.0 0.1 0.0 0.0 59.8 0.1 7.8 0.1 0.1 0.2 0.7 19.4 17.4 0.0 0.2 4.2 0.2 12.3 0.2 0.0 0.0 0.0 3.7 0.1 1.1 0.0 40.4 1.0 3.6 0.1 11.9 10.5 11.5 0.1 0.4 16.7 87.8 1.1 0.0 11.4 43.2 0.0 0.2 54.1 0.8 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.1 0.0 0.6 0.6 1.1 1.0 0.6 0.3 2.8 1.3 2.8 0.5 0.6 1.5 0.2 19.2 19.5 0.0 0.0 11.7 4.7 10.5 26.7 0.3 5.1 2.9 3.7 4.3 16.5 5.5 0.0 0.2 0.2 10.8 1.9 4.4 0.0 4.3 0.6 0.3 20.4 1.3 0.3 0.5 0.2 0.5 12.8 8.9 12.6 0.2 0.0 0.0 0.0 0.0 0.1 5.7 2.0 0.6 2.1 0.1 0.9 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.1 8.4 7.4 1.9 1.2 4.6 19.3 3.4 13.1 0.1 0.0 0.7 0.7 0.1 1.2 94.1 25.9 0.0 0.4 0.4 15.5 12.9 EVPLL ENSG00000214860 "Envoplakin like" A8MZ36 17 18377778-18389647 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 16.9;skin 1: 6.0;vagina: 8.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.1;Basal squamous epithelial cells: 8.0;Spermatogonia: 5.8;Squamous epithelial cells: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.2;HaCaT: 1.1;HeLa: 2.4;hTCEpi: 7.1;RT4: 2.5;SiHa: 1.3;T-47d: 2.1" HPA045728 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "HPA045728: AB_10960394" "unprognostic (1.34e-1)" "unprognostic (4.88e-2)" "unprognostic (2.06e-5)" "unprognostic (1.58e-1)" "unprognostic (2.08e-2)" "unprognostic (1.64e-2)" "unprognostic (3.07e-1)" "unprognostic (3.62e-1)" "unprognostic (4.60e-4)" "unprognostic (5.28e-2)" "unprognostic (2.58e-1)" "unprognostic (1.43e-2)" "unprognostic (5.06e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.1 0.1 0.0 0.2 16.9 0.1 0.0 0.0 0.0 0.0 1.2 2.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.0 1.9 0.2 0.0 6.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.4 1.1 0.0 0.1 2.2 8.6 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 1.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.5 1.6 1.3 8.0 0.0 0.1 0.6 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 5.8 10.9 1.3 0.0 0.0 0.0 0.2 1.0 FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 3691.0;vagina: 2600.3" "Cell type enhanced" "Detected in all" "Adipocytes: 2511.2;Alveolar cells type 2: 1891.0;Hofbauer cells: 2385.2;Squamous epithelial cells: 9211.0" "Group enriched" "Detected in all" 4 "cervical cancer: 268.3;head and neck cancer: 288.8;urothelial cancer: 73.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 1167.2;MOLT-4: 1213.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 14000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: AB_2681654" "unprognostic (8.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.54e-2)" "unprognostic (9.04e-2)" "unprognostic (1.33e-3)" "unprognostic (1.37e-1)" "unprognostic (1.95e-3)" "unprognostic (4.03e-3)" "unprognostic (2.71e-1)" "unprognostic (3.13e-1)" "unprognostic (6.16e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (4.69e-10)" "unprognostic (1.99e-1)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" 379.8 15.5 107.9 137.8 112.9 111.8 241.8 112.3 146.5 1340.4 307.4 256.7 83.3 62.7 4.8 3691.0 22.4 87.7 343.4 116.6 130.7 34.0 27.5 272.5 191.4 162.8 120.5 12.1 73.1 443.0 32.7 338.8 155.7 22.9 210.6 33.3 514.9 17.1 119.1 692.7 122.3 52.4 133.1 127.4 181.2 45.1 118.2 137.6 74.9 306.1 292.9 362.3 2600.3 138.9 76.9 215.9 133.1 0.3 615.7 59.0 0.3 158.0 8.9 123.2 153.3 2.2 100.3 1167.2 86.7 38.3 1.1 69.2 328.9 254.8 103.7 597.6 603.2 449.0 136.2 345.0 54.2 421.6 107.9 45.0 507.0 146.8 306.1 121.3 708.9 328.6 125.9 124.1 73.7 69.3 1213.7 199.9 170.5 785.1 732.1 526.0 0.4 127.7 198.9 951.4 514.4 190.7 74.1 24.7 61.0 230.2 1.2 201.6 97.0 0.1 331.3 1.6 1.4 155.6 70.1 902.2 52.2 396.8 184.9 8.1 14.3 0.9 6.1 16.6 9.3 17.2 6.9 13.7 55.9 10.4 3.1 11.9 5.2 22.3 5.5 54.8 9.8 13.4 107.9 112.9 112.3 146.5 116.6 130.7 162.8 120.5 155.7 133.1 118.2 138.9 2511.2 288.4 1891.0 30.7 93.0 121.0 90.0 881.2 727.3 23.7 22.3 48.6 5.7 2.8 649.8 22.0 45.9 28.0 97.5 420.3 3.9 35.4 29.5 55.7 579.5 662.2 197.2 74.4 7.7 23.8 272.4 140.6 278.8 29.6 55.8 70.1 35.3 1.4 2385.2 21.9 10.9 216.3 175.0 182.2 764.3 46.0 6.2 405.5 206.3 4.7 697.1 273.0 15.5 6.0 16.3 43.3 561.0 5.3 132.9 71.3 10.4 2.3 115.7 43.5 361.6 140.0 336.8 179.4 182.5 9211.0 168.6 27.0 102.3 68.8 419.2 232.6 FAM83D "C20orf129, CHICA, dJ616B8.3" ENSG00000101447 "Family with sequence similarity 83 member D" Q9H4H8 20 38926312-38953106 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 84.7;intestine: 83.1;smooth muscle: 95.3" "Group enriched" "Detected in many" 4 "Basal squamous epithelial cells: 44.9;Erythroid cells: 72.6;Extravillous trophoblasts: 67.5;Squamous epithelial cells: 71.7;Syncytiotrophoblasts: 152.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 1.1;NK-cells: 1.1;T-cells: 2.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049333, HPA060854" Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitotic spindle" "Microtubules, Cytokinetic bridge, Cytosol" "HPA049333: AB_2680717, HPA060854: " "unprognostic (7.90e-3)" "unprognostic (4.34e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (5.44e-6)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.73e-5)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.81e-14)" "unprognostic (2.57e-3)" "unprognostic (5.74e-2)" "unprognostic (2.82e-1)" "unprognostic (4.87e-2)" 1.6 1.8 0.8 7.2 1.6 23.3 1.1 0.9 1.4 4.1 0.2 83.1 8.4 1.0 1.6 84.7 1.0 13.6 1.0 0.9 0.5 5.7 3.7 5.2 4.5 0.5 0.4 0.5 0.4 0.2 0.4 3.4 0.5 16.2 8.6 0.2 7.8 1.7 0.2 10.2 34.7 95.3 0.5 1.9 44.9 5.0 0.5 6.6 1.0 0.2 12.2 27.0 17.1 0.9 112.2 67.3 52.0 44.0 5.8 6.5 93.6 49.3 30.2 94.7 57.4 103.4 49.7 28.3 47.6 32.1 73.4 93.1 71.8 83.9 87.9 9.4 28.6 32.6 50.7 75.2 4.7 14.6 16.5 3.3 4.2 54.6 31.4 11.4 52.7 12.3 29.6 39.5 54.4 59.7 22.7 21.3 43.2 64.4 85.1 21.8 96.0 15.6 27.6 28.0 24.3 40.2 143.0 117.4 20.6 48.1 73.6 14.9 25.4 62.4 76.4 71.6 110.1 12.0 19.6 29.0 28.1 21.2 46.7 0.0 0.0 0.0 0.2 0.1 0.9 0.6 1.0 1.1 0.0 1.1 1.1 1.4 0.0 1.1 0.1 0.0 2.0 0.5 0.8 1.6 0.9 1.4 0.9 0.5 0.5 0.4 0.5 0.5 0.5 0.9 3.9 0.0 1.3 0.3 2.3 2.3 5.8 7.0 44.9 0.0 2.8 9.0 0.8 1.5 18.0 0.0 0.0 17.3 6.3 6.5 0.0 0.1 0.5 1.1 1.6 2.2 1.8 72.6 3.7 0.0 67.5 2.7 18.3 2.1 0.0 8.2 1.8 5.7 4.8 0.0 1.2 6.0 4.1 1.6 0.5 0.6 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.1 6.0 0.0 12.5 1.6 1.7 8.3 4.5 0.0 19.7 0.3 4.0 15.7 18.3 71.7 1.8 152.6 5.2 0.3 10.2 4.1 FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.3;skin 1: 67.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 77.8;Basal squamous epithelial cells: 39.3;Distal enterocytes: 46.5;Squamous epithelial cells: 55.3;Suprabasal keratinocytes: 68.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA023369: AB_1848415, HPA023940: AB_1848416" "unprognostic (2.12e-2)" "unprognostic (5.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-3)" "unprognostic (2.04e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.58e-6)" "unprognostic (9.68e-2)" "unprognostic (5.13e-2)" "unprognostic (3.74e-2)" 2.3 2.2 0.8 2.9 0.8 1.4 2.8 0.8 1.2 10.8 2.1 8.2 10.8 2.5 0.9 51.3 1.6 6.4 17.2 0.8 1.9 7.1 21.7 3.2 3.0 1.6 1.4 1.4 9.5 6.4 4.3 0.7 2.7 3.5 5.3 0.2 10.9 2.2 6.9 67.3 11.3 1.5 0.9 2.0 9.8 1.0 1.4 3.7 5.6 0.8 5.7 2.5 17.0 0.7 24.7 22.4 0.2 0.0 0.7 2.0 35.9 25.2 11.0 21.0 15.7 28.7 8.8 16.1 15.1 16.7 17.1 28.6 3.6 21.1 9.6 13.2 8.1 0.4 11.2 15.9 15.3 2.9 7.9 2.8 38.9 13.6 22.3 7.9 7.6 2.5 7.7 0.5 6.0 15.0 0.7 6.0 11.0 34.1 0.1 0.1 0.0 7.8 10.1 6.2 11.2 0.0 8.7 5.3 1.5 29.1 9.2 3.6 14.2 12.9 21.6 6.1 29.8 2.2 4.0 4.1 10.1 0.1 8.6 1.1 0.0 0.0 0.7 0.0 0.3 0.3 0.4 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.8 0.8 0.8 1.2 0.8 1.9 1.6 1.4 2.7 0.9 1.4 0.7 0.6 3.2 2.2 0.0 2.5 77.8 12.2 9.9 39.3 0.2 7.1 2.9 5.1 11.5 6.3 7.3 0.0 0.4 0.7 46.5 0.0 15.8 0.1 2.4 1.0 1.9 7.1 2.7 0.1 10.0 9.7 2.6 17.3 5.0 8.9 3.5 1.1 20.9 1.2 0.0 0.1 17.7 8.2 0.3 7.8 1.9 0.0 1.0 5.4 0.0 1.0 0.2 3.1 0.5 0.0 24.3 22.8 0.0 3.0 13.2 15.3 4.4 2.5 0.4 0.0 1.3 2.0 0.1 1.0 55.3 68.5 1.9 2.6 0.0 17.1 9.1 FAM83H FLJ46072 ENSG00000180921 "Family with sequence similarity 83 member H" Q6ZRV2 8 143723933-143738234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 70.5;skin 1: 34.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 58.7;hTCEpi: 59.8;MCF7: 118.2;OE19: 62.4;RT4: 70.1;T-47d: 58.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024505, HPA024604" Enhanced Approved Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA024505: AB_1848417, HPA024604: AB_1848418" "unprognostic (3.80e-2)" "unprognostic (3.75e-3)" "unprognostic (6.87e-2)" "unprognostic (1.63e-2)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.93e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (3.95e-2)" "unprognostic (9.69e-3)" "prognostic favorable (4.42e-4)" "unprognostic (5.54e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" 2.1 4.0 1.9 2.1 1.7 0.5 4.4 1.2 2.2 11.5 2.6 9.8 8.4 0.8 3.3 70.5 4.7 3.3 0.8 2.0 1.1 11.8 13.5 6.3 0.9 1.6 2.4 0.3 13.9 7.9 5.9 3.5 1.5 7.2 4.3 1.1 17.1 3.8 0.1 34.9 9.1 0.3 1.3 1.7 11.0 2.8 1.5 1.5 14.1 0.0 4.0 8.3 23.2 2.2 47.0 28.3 0.3 0.1 0.1 0.0 16.6 4.0 0.0 2.0 0.7 25.8 53.4 0.0 6.1 1.0 0.0 56.1 3.5 51.9 0.9 0.0 0.2 1.5 58.7 18.3 4.3 0.6 1.7 2.9 59.8 0.2 15.0 0.8 0.0 4.2 22.2 0.1 0.0 118.2 0.8 0.4 4.8 62.4 15.3 0.1 0.1 6.0 16.5 70.1 7.1 0.2 38.3 53.8 7.8 7.5 58.2 8.2 0.3 0.1 7.2 3.9 0.2 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 1.2 2.2 2.0 1.1 1.6 2.4 1.5 1.3 1.5 2.2 0.1 32.1 16.5 0.7 0.6 22.8 17.7 21.9 6.8 2.0 18.2 14.0 4.6 14.3 18.9 29.5 2.1 12.8 0.5 38.5 3.9 22.0 1.2 11.4 2.9 1.0 14.4 0.0 1.3 25.9 17.8 1.6 25.0 25.9 0.0 5.4 0.7 25.5 4.7 10.1 0.5 24.3 16.2 2.8 0.8 0.7 0.0 1.3 1.8 0.0 2.8 6.6 2.1 0.5 0.1 42.7 27.2 0.4 0.4 26.4 23.6 7.0 17.4 2.0 0.0 0.2 1.9 1.7 1.0 38.9 26.9 14.6 0.9 1.2 27.8 33.9 FAT2 "CDHF8, CDHR9, HFAT2, MEGF1" ENSG00000086570 "FAT atypical cadherin 2" Q9NYQ8 5 151504093-151568944 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 113.4;esophagus: 50.9;skin 1: 56.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.0;Basal respiratory cells: 31.6;Basal squamous epithelial cells: 27.9;Early spermatids: 16.0;Extravillous trophoblasts: 20.6;Squamous epithelial cells: 53.2;Suprabasal keratinocytes: 19.6" "Group enriched" "Detected in many" 6 "cervical cancer: 13.9;head and neck cancer: 21.4;lung cancer: 6.1;urothelial cancer: 5.6" "Region enriched" "Detected in many" 7 "cerebellum: 113.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BEWO: 35.1;EFO-21: 21.0;HaCaT: 51.7;HBEC3-KT: 23.6;hTCEpi: 70.5" "Region enriched" "Detected in some" 18 "cerebellum: 32.0" "Region enriched" "Detected in many" 56 "cerebellum: 224.4" CAB033680 Enhanced NA NA 300000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB033680: AB_2100956" "unprognostic (8.06e-3)" "unprognostic (6.01e-2)" "unprognostic (3.47e-1)" "unprognostic (4.80e-3)" "unprognostic (1.33e-1)" "unprognostic (4.43e-1)" "unprognostic (9.78e-3)" "unprognostic (2.28e-1)" "unprognostic (8.25e-2)" "unprognostic (2.65e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-7)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (6.77e-2)" "unprognostic (3.64e-3)" 0.4 0.2 0.4 0.0 3.8 0.1 3.6 113.4 4.8 11.5 0.0 0.1 0.1 0.1 1.7 50.9 1.0 0.0 0.1 0.5 0.4 0.6 0.1 0.2 0.0 15.1 2.8 0.1 0.2 0.2 0.5 0.9 17.2 5.3 0.0 0.1 8.9 4.8 0.2 56.0 0.2 0.0 0.4 0.1 0.1 13.2 0.5 2.2 0.1 0.0 3.4 2.9 24.4 2.2 1.7 0.0 0.0 0.1 0.0 0.0 35.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 21.0 0.0 0.2 51.7 0.0 23.6 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 70.5 0.0 3.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.7 0.1 0.0 0.1 1.1 0.2 0.5 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.8 113.4 4.8 0.5 0.4 15.1 2.8 17.2 0.4 0.5 2.2 0.1 0.0 0.0 0.7 0.0 18.0 5.8 31.6 27.9 0.0 3.4 12.8 1.9 0.0 11.1 1.8 0.0 0.4 0.0 0.0 0.0 0.0 16.0 0.1 0.0 0.3 0.0 0.0 5.0 0.0 20.6 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 2.9 0.0 0.0 0.0 1.5 7.8 0.0 0.0 7.2 0.0 0.0 0.0 0.0 4.0 0.9 0.0 0.0 0.0 0.0 1.2 0.0 0.1 3.0 0.0 0.0 0.0 0.4 0.5 0.1 53.2 19.6 1.0 0.1 0.0 0.0 13.0 FGFBP1 "FGFBP, HBP17" ENSG00000137440 "Fibroblast growth factor binding protein 1" Q14512 4 15935577-15938740 "Cancer-related genes, Predicted secreted proteins" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 117.1;esophagus: 421.8;vagina: 172.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1044.3;Basal respiratory cells: 596.2;Squamous epithelial cells: 528.5;Suprabasal keratinocytes: 786.2;Urothelial cells: 303.6" "Group enriched" "Detected in many" 5 "cervical cancer: 117.5;head and neck cancer: 246.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 556.3;HBEC3-KT: 968.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004332 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA004332: AB_1078856" "unprognostic (2.87e-3)" "unprognostic (3.55e-1)" "unprognostic (5.03e-2)" "unprognostic (6.99e-2)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (5.03e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-2)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (3.31e-3)" 0.6 0.1 0.0 1.7 0.0 0.1 13.5 0.0 0.0 117.1 0.0 22.1 1.8 0.5 0.1 421.8 1.2 0.3 0.2 0.0 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.1 0.4 0.0 0.2 1.1 0.0 1.7 15.6 0.0 59.7 0.1 0.1 91.2 7.0 1.1 0.0 0.1 2.0 0.0 0.0 0.3 0.7 0.0 38.4 14.9 172.3 0.0 150.7 10.5 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 189.0 0.0 10.9 0.0 0.2 556.3 0.0 968.2 0.0 0.0 1.2 0.0 2.0 0.0 0.2 0.0 0.4 0.1 141.0 0.0 17.7 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 7.9 75.2 0.0 0.0 0.0 93.4 6.7 0.0 0.0 0.2 0.0 0.2 0.0 0.9 0.5 0.1 0.2 0.3 0.0 0.3 0.0 0.1 0.2 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 8.4 0.0 0.3 1044.3 182.5 596.2 217.4 0.0 11.8 3.2 0.1 0.0 223.2 0.0 0.0 0.2 0.2 49.6 0.0 49.7 0.0 52.8 3.3 6.3 0.0 0.0 0.0 7.5 2.4 6.2 0.0 65.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.1 42.7 0.0 60.6 0.0 0.0 0.9 74.7 0.0 0.6 0.0 1.0 0.0 0.0 139.1 50.8 0.0 0.0 90.8 0.7 0.0 56.8 0.0 0.0 0.0 10.4 0.0 0.0 528.5 786.2 2.3 2.1 0.0 26.1 303.6 FOXN1 "FKHL20, RONU, WHN" ENSG00000109101 "Forkhead box N1" O15353 17 28506243-28538900 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 18.4;lymphoid tissue: 10.7;skin 1: 41.1;vagina: 10.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.0;Prostatic glandular cells: 5.9;Squamous epithelial cells: 15.9;Suprabasal keratinocytes: 12.4;Urothelial cells: 15.4" "Cancer enhanced" "Detected in many" "cervical cancer: 7.0;head and neck cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HaCaT: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.60e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.68e-3)" "unprognostic (5.98e-6)" "prognostic favorable (5.00e-4)" "unprognostic (2.85e-1)" "unprognostic (2.56e-1)" "unprognostic (3.89e-2)" "unprognostic (7.08e-3)" "unprognostic (1.26e-2)" "unprognostic (1.90e-3)" "unprognostic (4.68e-2)" "unprognostic (3.96e-1)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.0 18.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 2.4 0.1 0.1 41.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 10.7 0.1 0.0 5.6 0.8 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.9 1.8 1.2 0.0 0.4 0.6 0.4 0.0 0.3 0.0 0.0 0.8 0.0 2.2 0.0 0.0 0.8 0.3 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.9 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 15.9 12.4 1.1 0.1 0.0 0.4 15.4 FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 107.2;urinary bladder: 53.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.4;Basal respiratory cells: 24.9;Collecting duct cells: 40.5;Gastric mucus-secreting cells: 67.2;Suprabasal keratinocytes: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 39.0;HaCaT: 44.7;Hep G2: 93.8;OE19: 117.1;RT4: 38.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059700 Supported Nucleoplasm Yes NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059700: AB_2684107" "unprognostic (2.04e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.18e-2)" "unprognostic (1.50e-3)" "unprognostic (2.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.68e-4)" "unprognostic (1.49e-2)" "unprognostic (3.16e-3)" "unprognostic (2.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 0.3 0.0 6.9 0.2 5.2 0.0 1.4 7.1 7.1 6.7 3.8 0.8 10.4 0.9 0.3 11.3 3.9 5.4 0.0 4.7 5.1 9.8 6.4 4.0 0.0 5.6 6.0 0.0 6.5 0.1 2.5 1.1 6.0 8.9 0.4 0.1 30.4 1.1 0.2 25.7 0.6 0.0 5.3 0.0 107.2 0.2 7.5 0.6 3.6 0.6 8.0 53.5 16.9 4.7 16.0 1.4 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.1 0.1 39.0 22.6 0.0 0.7 0.0 0.1 44.7 0.0 1.7 0.0 0.0 1.1 0.0 8.2 93.8 0.0 0.0 2.4 0.0 16.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 117.1 0.8 0.0 0.0 0.0 0.4 38.2 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 5.2 7.1 7.1 4.7 5.1 5.6 6.0 6.0 5.3 7.5 4.7 0.3 16.0 10.6 0.0 0.0 60.4 3.2 24.9 6.8 0.0 5.3 5.1 0.8 0.0 16.8 40.5 0.0 0.0 0.0 0.0 1.9 3.0 0.0 5.2 3.0 0.4 0.0 0.0 1.2 13.4 0.0 1.4 67.2 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 2.9 0.0 0.0 0.7 1.8 15.9 0.0 0.0 0.0 0.0 0.5 11.8 0.0 0.0 0.2 0.6 0.0 6.2 5.0 0.0 0.0 0.0 1.6 0.0 0.0 22.2 45.5 0.0 0.3 0.0 0.0 3.9 GBP6 DKFZp686G0786 ENSG00000183347 "Guanylate binding protein family member 6" Q6ZN66 1 89364059-89388160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 327.3" "Cell type enriched" "Detected in some" 25 "Squamous epithelial cells: 325.0" "Group enriched" "Detected in many" 7 "cervical cancer: 21.7;head and neck cancer: 38.1;lung cancer: 14.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "A-431: 5.4;HaCaT: 11.3" "Low region specificity" "Detected in all" HPA027744 Enhanced NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA027744: AB_10602809" "unprognostic (7.60e-3)" "unprognostic (6.83e-2)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (7.05e-3)" "unprognostic (5.85e-2)" "unprognostic (5.66e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "unprognostic (7.99e-4)" "unprognostic (1.63e-1)" "unprognostic (2.04e-6)" "unprognostic (1.43e-1)" "unprognostic (1.03e-1)" "unprognostic (3.41e-1)" "unprognostic (3.91e-3)" 0.0 0.0 0.3 0.2 0.3 0.2 0.2 0.3 0.4 25.9 0.1 0.0 0.0 0.1 0.1 327.3 0.3 0.2 0.1 0.3 0.2 0.0 0.1 0.3 0.1 0.5 0.2 0.4 0.1 0.0 0.8 0.0 0.5 0.1 0.0 0.1 62.8 0.1 0.2 0.9 0.0 0.0 0.3 0.2 0.3 0.0 0.3 1.1 0.2 0.2 55.0 0.1 32.0 0.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 11.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.0 0.1 0.3 0.3 0.7 0.2 0.1 0.1 0.6 0.1 0.3 0.3 0.3 0.4 0.3 0.2 0.5 0.2 0.5 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 5.2 12.5 0.1 0.0 0.0 0.2 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.5 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.4 0.0 0.0 12.8 0.0 0.0 0.0 1.2 0.0 0.1 325.0 0.0 0.0 0.2 1.2 0.0 1.2 GJB5 CX31.1 ENSG00000189280 "Gap junction protein beta 5" O95377 1 34755047-34758512 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "esophagus: 101.0;skin 1: 95.1;vagina: 35.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 48.6;Basal prostatic cells: 38.0;Basal respiratory cells: 49.6;Squamous epithelial cells: 63.8;Suprabasal keratinocytes: 83.5;Urothelial cells: 66.2" "Cancer enhanced" "Detected in many" "cervical cancer: 36.7;head and neck cancer: 57.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 29.1;HaCaT: 90.8;HBEC3-KT: 40.7;hTCEpi: 147.4;RT4: 50.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038146 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038146: AB_10697242" "unprognostic (2.62e-1)" "unprognostic (1.63e-1)" "unprognostic (3.48e-1)" "unprognostic (5.71e-2)" "unprognostic (8.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.89e-2)" "unprognostic (2.76e-2)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.30e-2)" "unprognostic (1.09e-3)" "unprognostic (2.36e-1)" "unprognostic (2.41e-3)" "unprognostic (5.59e-2)" "unprognostic (5.67e-3)" 0.2 0.1 1.0 0.0 1.0 0.0 3.9 0.6 1.3 12.8 0.0 0.1 0.0 0.1 3.4 101.0 0.6 3.4 0.1 1.4 0.3 0.1 0.4 0.3 0.0 0.4 0.4 0.1 1.1 0.0 0.8 0.6 0.5 5.2 0.1 0.0 13.9 3.1 0.3 95.1 0.2 0.0 0.6 0.1 0.1 2.3 0.7 1.4 0.9 0.1 12.6 7.1 35.0 0.9 29.1 0.3 0.1 0.5 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 2.2 0.0 1.2 0.0 0.3 90.8 0.0 40.7 0.0 0.1 0.0 7.0 0.9 0.0 0.0 0.0 0.0 0.1 147.4 0.0 23.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 50.9 0.1 0.0 3.6 1.5 0.0 0.4 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.6 1.3 1.4 0.3 0.4 0.4 0.5 0.6 0.7 0.9 0.0 0.0 1.1 0.3 0.0 48.6 38.0 49.6 12.5 0.0 2.8 1.9 0.5 0.0 17.2 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 4.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.5 0.0 0.0 12.4 0.0 0.0 0.0 1.4 0.0 0.0 63.8 83.5 0.4 0.2 0.0 0.3 66.2 GJB6 "CX30, DFNA3, ED2, EDH, HED" ENSG00000121742 "Gap junction protein beta 6" O95452 13 20221962-20232365 "Disease related genes, Human disease related genes, Predicted membrane proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.6;esophagus: 195.4;vagina: 139.3" "Cell type enhanced" "Detected in some" "Astrocytes: 58.8;Basal keratinocytes: 12.2;Basal respiratory cells: 15.6;Ionocytes: 12.2;Squamous epithelial cells: 31.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 145.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.6" "Lineage enriched" "Detected in single" 5 "T-cells: 2.6" "Cell line enriched" "Detected in some" 10 "RT4: 186.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014846 Supported "Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA014846: AB_1847135" "unprognostic (5.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "unprognostic (7.90e-2)" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.83e-1)" "unprognostic (8.96e-2)" "unprognostic (9.64e-2)" "unprognostic (2.82e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-2)" "unprognostic (1.14e-11)" "unprognostic (8.99e-2)" "unprognostic (1.16e-1)" "unprognostic (6.35e-3)" "unprognostic (5.04e-2)" 0.5 0.2 55.8 0.3 59.4 95.6 3.8 73.0 80.9 65.9 36.0 0.0 0.0 0.9 0.2 195.4 0.4 1.3 0.1 50.2 63.5 0.0 0.1 0.3 0.8 60.0 71.8 0.0 0.1 0.0 4.4 0.0 57.5 0.2 0.1 0.0 34.5 0.0 0.1 56.8 0.2 0.0 47.7 0.2 0.3 1.4 76.3 37.6 5.3 0.0 15.4 10.3 139.3 42.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 4.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 186.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 1.1 0.6 0.5 0.0 0.0 0.0 2.6 0.2 55.8 59.4 73.0 80.9 50.2 63.5 60.0 71.8 57.5 47.7 76.3 42.7 0.0 0.0 0.0 58.8 0.0 12.2 1.7 15.6 4.0 0.0 0.0 0.1 0.6 0.0 4.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 6.9 5.8 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 12.2 0.0 0.4 4.6 0.0 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.1 0.3 31.0 3.8 0.0 0.3 0.0 0.0 2.4 GLTP ENSG00000139433 "Glycolipid transfer protein" Q9NZD2 12 109850945-109880541 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 334.1;skin 1: 276.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 266.5;Suprabasal keratinocytes: 479.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056461, HPA065503" Approved Supported Cytosol NA NA 25000 "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA056461: AB_2683138, HPA065503: " "unprognostic (1.18e-1)" "prognostic favorable (2.01e-5)" "unprognostic (7.46e-2)" "unprognostic (6.22e-3)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (6.63e-2)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (2.47e-1)" "unprognostic (3.03e-1)" "unprognostic (4.83e-2)" "unprognostic (4.46e-2)" "unprognostic (2.20e-1)" "prognostic favorable (4.17e-6)" "unprognostic (3.28e-2)" 19.0 21.7 59.1 17.5 98.8 19.3 27.1 93.6 75.1 94.4 43.1 38.4 14.6 15.9 34.8 334.1 13.6 14.2 21.0 62.3 69.9 53.2 15.1 24.4 19.3 110.3 89.5 18.2 23.8 31.4 12.5 17.8 102.5 29.4 31.8 7.0 84.7 19.1 18.6 276.6 32.1 18.8 84.0 21.5 21.6 16.3 87.3 18.0 23.5 18.1 108.2 33.6 178.0 138.5 39.3 27.9 15.5 16.7 36.2 41.4 11.0 47.4 58.2 36.0 29.7 11.3 14.9 34.5 25.3 57.8 17.5 47.3 24.2 54.9 50.7 35.0 21.5 22.6 15.9 16.5 31.6 24.6 25.5 30.1 68.8 64.6 45.3 53.9 61.3 34.8 10.1 22.5 53.2 52.9 33.6 19.8 28.1 32.0 36.8 29.3 36.4 36.3 20.5 116.1 20.0 19.8 30.1 77.1 26.0 14.1 36.1 8.6 83.2 41.4 21.9 61.5 36.5 30.1 27.7 23.8 83.0 25.1 25.9 42.6 65.7 37.3 51.5 66.0 32.4 23.9 31.0 46.5 48.8 21.5 20.1 35.8 32.9 42.4 57.0 8.0 37.6 40.6 59.1 98.8 93.6 75.1 62.3 69.9 110.3 89.5 102.5 84.0 87.3 138.5 48.1 25.6 60.9 10.4 37.5 145.4 109.1 72.1 88.2 11.4 55.6 44.4 14.6 18.6 62.7 44.1 14.6 86.5 48.3 95.6 199.6 39.0 20.5 30.1 33.3 47.9 32.4 10.1 9.9 56.5 20.0 35.0 28.5 59.1 20.8 19.0 34.2 15.3 34.5 13.5 11.4 39.2 50.8 61.6 84.6 11.7 23.0 55.3 60.5 13.1 61.8 23.4 64.9 21.6 140.1 53.5 40.0 18.0 26.2 80.6 102.3 38.2 25.2 12.3 39.5 23.5 37.3 22.9 20.8 266.5 479.2 210.6 46.3 31.4 59.1 129.0 GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.2;kidney: 61.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.1;Basal squamous epithelial cells: 104.7;Prostatic glandular cells: 79.0;Squamous epithelial cells: 124.7;Syncytiotrophoblasts: 98.6;Urothelial cells: 79.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "OE19: 1706.0" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in many" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" 5.9 0.1 0.0 0.7 0.4 0.0 14.2 5.6 0.4 13.5 4.5 8.1 11.8 3.3 3.8 60.2 22.3 9.5 1.2 0.2 0.0 61.5 11.1 10.6 0.1 0.0 0.4 1.0 32.7 11.4 6.9 11.9 0.5 14.5 10.0 0.1 25.2 11.6 0.3 39.9 10.8 1.0 0.0 0.5 16.9 1.2 0.1 1.1 6.6 0.1 8.7 7.5 26.2 0.3 12.6 14.4 0.0 0.0 0.0 0.0 19.1 0.0 0.8 0.1 0.5 44.7 24.3 0.0 4.2 0.4 0.9 24.1 0.0 16.1 0.0 0.0 2.1 0.0 6.4 38.5 0.0 0.0 0.0 0.0 15.1 0.2 3.7 2.5 0.1 0.0 0.0 0.0 0.0 11.5 0.2 0.1 4.9 1706.0 3.4 0.1 0.0 18.6 18.5 14.0 9.5 0.1 18.4 370.7 0.1 17.3 14.0 0.0 0.0 0.0 1.1 0.2 0.0 0.2 0.1 1.0 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.6 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.3 0.5 22.4 15.1 0.0 0.9 38.2 77.1 20.0 104.7 0.2 48.2 30.5 2.5 17.2 18.2 22.0 0.0 35.7 0.7 25.6 9.8 35.6 0.0 30.2 5.3 2.6 14.4 0.0 0.3 19.4 27.4 3.1 27.0 41.8 1.3 0.5 0.4 5.1 2.8 0.0 0.0 19.7 40.7 0.0 2.3 0.0 2.8 1.3 5.4 0.0 1.6 0.4 0.0 0.0 0.0 26.7 26.0 1.2 0.3 79.0 28.3 13.8 20.9 0.1 0.0 0.9 2.1 0.4 0.3 124.7 41.9 98.6 1.4 0.0 21.1 79.7 GRHL3 "SOM, TFCP2L4" ENSG00000158055 "Grainyhead like transcription factor 3" Q8TE85 1 24319357-24364482 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 120.8;skin 1: 53.5;vagina: 47.7" "Group enriched" "Detected in some" 5 "Squamous epithelial cells: 113.5;Suprabasal keratinocytes: 99.3;Urothelial cells: 78.4" "Group enriched" "Detected in many" 4 "cervical cancer: 13.3;head and neck cancer: 16.1;urothelial cancer: 28.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 46.1;HaCaT: 36.6;MCF7: 58.5;OE19: 21.2;RT4: 64.8;SuSa: 33.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA059960 Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059960: AB_2684180" "unprognostic (8.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.95e-2)" "unprognostic (7.83e-3)" "unprognostic (7.58e-3)" "unprognostic (6.28e-3)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (9.01e-3)" "unprognostic (4.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.36e-2)" "unprognostic (8.59e-4)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (7.42e-2)" 0.2 0.1 0.4 0.3 0.4 0.1 1.9 1.4 0.6 23.3 0.1 0.1 0.6 0.1 1.6 120.8 0.6 0.7 0.0 0.3 1.3 0.2 0.3 0.1 0.0 3.8 4.6 0.0 0.2 0.9 0.2 1.4 3.4 1.5 0.2 0.1 16.7 1.6 0.1 53.5 0.3 0.0 2.3 0.0 0.5 2.3 0.8 1.0 0.0 0.0 25.1 34.7 47.7 1.9 1.2 2.7 1.0 0.0 0.0 0.0 46.1 0.0 0.0 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 36.6 0.1 3.3 0.0 1.2 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 14.2 0.2 2.7 0.0 0.0 0.0 0.2 0.1 0.0 58.5 0.0 0.2 2.4 21.2 0.0 0.0 0.0 0.2 4.6 64.8 0.3 0.0 0.2 6.3 0.0 33.3 4.2 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.4 0.6 0.3 1.3 3.8 4.6 3.4 2.3 0.8 1.9 0.0 0.0 0.6 0.0 0.0 14.4 13.2 5.2 8.6 0.0 1.1 0.3 0.5 0.0 6.4 1.8 0.0 4.1 0.0 0.9 0.0 0.4 0.5 3.8 0.1 0.3 0.0 0.0 0.1 0.0 0.8 0.3 0.0 1.3 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.1 2.0 0.3 2.1 0.3 0.0 0.3 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.1 0.2 0.0 3.3 0.0 0.0 0.0 0.3 2.6 0.0 113.5 99.3 18.5 0.0 0.0 0.1 78.4 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583742-67586656 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2087.9" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 4033.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 4998.3;OE19: 7810.3" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol No No 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitochondria, Cytosol" "HPA019779: AB_1849799, HPA019869: AB_1849801" "unprognostic (9.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.24e-2)" "unprognostic (2.72e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-3)" "unprognostic (3.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (2.14e-3)" "unprognostic (9.37e-2)" "unprognostic (5.72e-2)" "unprognostic (7.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" 290.5 276.2 346.8 232.1 370.3 601.3 288.7 358.9 425.7 641.9 695.8 329.6 394.6 331.9 280.3 2087.9 647.5 435.8 367.2 341.4 381.9 567.7 45.1 468.3 321.8 375.7 379.2 306.9 340.9 737.4 320.2 326.9 378.5 291.7 197.1 137.9 541.2 780.4 355.0 731.4 321.7 214.2 367.0 257.2 535.5 45.8 378.1 296.9 579.0 312.5 380.8 526.5 946.2 377.7 1202.5 1599.4 763.7 1198.9 577.8 645.2 705.3 511.3 678.1 761.2 589.3 2956.3 1225.0 3.3 1144.7 813.5 683.7 1707.8 2073.9 2248.5 214.4 848.0 765.3 59.9 1107.6 0.5 852.2 400.3 667.6 807.2 4998.3 609.9 583.3 560.9 1160.2 847.2 1318.2 321.8 605.7 4.3 918.2 1100.6 1475.2 7810.3 681.3 844.8 129.6 3.8 1236.8 3.6 260.6 754.3 719.1 230.9 2394.0 598.2 3.6 656.3 634.5 351.6 883.8 740.6 378.6 200.0 1353.9 447.1 400.0 652.4 747.8 56.0 3145.4 246.6 720.0 2470.8 271.9 509.2 322.4 597.7 3582.7 476.3 267.8 466.5 130.5 1443.8 1608.5 1435.1 363.3 3948.4 346.8 370.3 358.9 425.7 341.4 381.9 375.7 379.2 378.5 367.0 378.1 377.7 466.7 1153.8 872.3 25.5 296.8 865.6 1914.8 3813.8 767.2 170.0 628.7 838.3 297.3 987.9 2763.5 1230.4 33.3 2116.8 372.4 655.0 1805.9 1811.9 4.9 1381.0 589.0 431.4 368.2 166.3 6.8 1444.4 1703.9 710.5 781.9 1020.9 269.9 795.0 382.3 10.5 861.2 70.7 10.1 992.4 1930.7 597.9 1090.3 25.5 572.3 703.5 1531.5 27.2 2166.5 558.5 459.3 17.6 38.4 1412.1 948.9 400.2 591.6 2266.2 844.4 3495.5 3715.4 274.4 361.6 401.3 941.7 4.8 54.9 4033.7 1061.7 1645.5 342.5 527.8 1118.5 3418.6 HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;skin 1: 30.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 84.7;Basal respiratory cells: 52.0;Basal squamous epithelial cells: 120.1;Ionocytes: 87.5;Langerhans cells: 124.0;Suprabasal keratinocytes: 106.1" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 5.9" "Immune cell enriched" "Detected in many" 5 "neutrophil: 176.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 176.7" "Cell line enriched" "Detected in some" 6 "HaCaT: 118.4" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" 22.2 0.3 0.1 9.8 0.2 22.1 7.6 0.1 5.9 8.9 0.2 0.7 0.9 0.2 0.3 40.8 0.7 0.8 0.9 0.3 0.1 3.9 2.9 11.9 0.6 0.1 0.1 0.1 0.2 5.5 0.3 4.5 1.2 3.4 0.3 0.2 14.2 14.7 0.2 30.2 1.0 0.3 0.1 25.9 1.5 2.7 0.2 10.5 0.5 1.9 10.2 6.9 14.0 0.1 4.5 0.4 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 118.4 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.1 3.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 19.5 0.2 0.0 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 38.7 2.5 2.6 0.0 5.3 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 176.7 0.0 23.9 0.0 0.0 1.4 0.1 0.2 0.1 5.9 0.3 0.1 0.1 0.1 1.2 0.1 0.2 0.1 0.4 0.0 4.3 0.0 0.5 94.4 84.7 52.0 120.1 0.5 3.4 1.1 0.1 0.0 40.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 24.9 0.4 0.2 1.2 0.0 0.0 0.0 0.0 26.3 2.4 0.0 0.3 2.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 87.5 4.1 124.0 2.7 0.0 17.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 8.5 0.1 0.0 0.1 1.4 0.0 0.1 47.2 106.1 2.6 1.5 0.0 0.0 32.5 HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;esophagus: 16.8;lymphoid tissue: 19.6;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 81.1;Basal respiratory cells: 57.3;Basal squamous epithelial cells: 159.4;Langerhans cells: 57.4;Squamous epithelial cells: 66.9;Suprabasal keratinocytes: 106.3;Urothelial cells: 66.1" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.7" "Group enriched" "Detected in many" 6 "basophil: 58.6;neutrophil: 177.2;non-classical monocyte: 84.4" "Group enriched" "Detected in many" 50 "granulocytes: 177.2;monocytes: 84.4" "Cell line enriched" "Detected in some" 4 "RT4: 37.1" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" 5.6 0.1 0.0 9.2 0.1 27.4 2.3 0.0 4.7 2.5 0.2 0.5 0.2 0.0 0.5 16.8 0.7 0.6 0.7 0.1 0.0 0.9 1.8 8.2 0.4 0.0 0.0 0.1 0.0 3.4 0.2 1.9 0.9 1.5 0.1 0.1 3.4 2.7 0.1 17.4 0.2 0.2 0.0 19.6 0.4 0.1 0.1 4.0 0.4 1.1 7.8 7.1 4.3 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 9.2 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 37.1 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 58.6 2.2 0.8 0.0 16.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 177.2 0.0 84.4 0.0 0.0 2.9 0.0 0.1 0.0 4.7 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 3.2 6.7 0.0 0.7 94.4 81.1 57.3 159.4 0.2 0.7 0.3 0.0 0.0 24.6 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 21.5 1.4 0.0 0.1 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 12.2 10.6 57.4 0.2 0.0 20.1 8.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 14.7 0.0 0.1 2.2 0.2 0.0 0.0 1.4 0.1 0.0 66.9 106.3 13.8 1.0 0.0 0.0 66.1 HES2 bHLHb40 ENSG00000069812 "Hes family bHLH transcription factor 2" Q9Y543 1 6412418-6424670 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 33.7;skin 1: 16.9;vagina: 18.8" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 48.9;Late spermatids: 45.3;Paneth cells: 33.0;Squamous epithelial cells: 58.5;Syncytiotrophoblasts: 99.3" "Cancer enhanced" "Detected in many" "cervical cancer: 17.0;head and neck cancer: 16.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 3.0;neutrophil: 1.3" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "BEWO: 19.7;HaCaT: 37.6;HBEC3-KT: 32.3;hTCEpi: 18.3;PC-3: 13.4;TIME: 55.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039462 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA039462: AB_10673533" "unprognostic (1.96e-1)" "unprognostic (7.00e-2)" "unprognostic (1.66e-1)" "unprognostic (6.82e-3)" "unprognostic (1.13e-2)" "unprognostic (1.89e-1)" "unprognostic (2.56e-4)" "unprognostic (4.74e-2)" "unprognostic (7.41e-2)" "unprognostic (3.20e-2)" "unprognostic (5.63e-3)" "unprognostic (1.38e-1)" "unprognostic (7.67e-2)" "unprognostic (5.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.14e-1)" "unprognostic (1.00e-2)" 0.1 0.0 0.2 0.8 0.2 0.4 0.8 0.4 0.4 9.8 0.2 6.1 0.3 0.3 0.6 33.7 2.6 0.1 0.1 0.3 0.2 1.1 0.1 1.1 0.1 0.3 0.2 0.1 0.0 0.3 0.2 6.7 0.4 1.6 4.6 1.2 3.7 0.1 0.1 16.9 1.3 0.3 0.1 0.1 0.1 2.9 0.2 0.3 0.0 0.1 1.7 0.3 18.8 0.7 1.8 0.6 0.0 0.2 0.3 0.1 19.7 0.0 0.0 0.1 0.0 0.5 0.3 0.1 3.5 0.2 0.2 37.6 1.0 32.3 0.0 0.0 0.4 0.3 0.4 0.3 0.3 0.0 0.2 0.1 18.3 0.1 0.7 0.0 9.8 0.0 0.3 0.3 0.1 2.9 0.1 1.6 0.0 2.0 13.4 0.1 0.0 0.2 0.3 0.5 0.2 0.0 1.9 10.3 0.3 1.9 1.4 0.7 55.1 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.1 3.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 1.3 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.4 0.4 0.3 0.2 0.3 0.2 0.4 0.1 0.2 0.7 0.4 9.6 3.9 0.0 0.4 6.5 8.7 10.5 8.0 1.8 2.0 1.5 9.1 0.0 12.7 1.8 4.2 3.6 0.4 17.3 0.0 1.1 19.4 10.3 1.2 1.5 3.0 0.0 0.0 0.0 4.6 1.1 0.0 9.9 1.3 0.2 1.4 0.2 0.9 0.0 0.0 48.9 6.1 0.6 4.8 45.3 0.3 1.2 1.8 0.0 0.1 1.0 1.0 0.0 0.0 0.5 33.0 0.7 0.3 10.9 9.2 6.6 16.8 6.1 0.0 1.4 0.9 5.8 4.8 58.5 19.6 99.3 0.8 0.1 13.1 23.2 HOXA1 "HOX1, HOX1F" ENSG00000105991 "Homeobox A1" 7 27092993-27096000 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "urinary bladder: 5.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 7.4;Enteroendocrine cells: 3.0;Kupffer cells: 3.2;Squamous epithelial cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "intermediate monocyte: 4.5;NK-cell: 4.8;non-classical monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;NK-cells: 4.8" "Cell line enhanced" "Detected in many" "HMC-1: 14.1" "Region enriched" "Detected in single" 7 "pons and medulla: 1.0" "Region enhanced" "Detected in some" "spinal cord: 2.6" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (7.39e-2)" "unprognostic (1.26e-3)" "unprognostic (1.05e-1)" "unprognostic (2.17e-4)" "unprognostic (2.79e-2)" "prognostic unfavorable (6.73e-5)" "unprognostic (4.70e-2)" "unprognostic (2.72e-2)" "unprognostic (6.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.11e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-4)" "unprognostic (2.03e-1)" "unprognostic (2.82e-1)" "unprognostic (5.77e-3)" "unprognostic (1.17e-1)" 0.6 0.5 0.0 0.7 0.0 0.3 0.6 0.0 0.0 0.4 0.0 1.1 0.3 0.4 1.9 2.9 0.8 0.3 0.0 0.0 0.0 0.9 0.2 0.3 1.3 1.1 0.0 1.6 0.0 1.1 0.0 0.1 0.5 0.5 1.0 0.0 0.0 0.4 0.2 2.2 1.1 0.3 0.7 1.2 0.7 0.1 0.0 0.7 0.1 0.0 1.1 5.3 0.5 0.7 6.3 2.6 0.2 3.4 0.0 0.0 5.6 0.8 3.5 2.2 2.6 13.8 3.8 4.2 7.9 2.1 8.5 13.2 4.6 3.7 1.6 0.3 13.9 5.5 0.2 0.1 0.7 4.8 14.1 2.4 3.8 2.6 5.5 0.0 3.5 4.2 6.1 0.0 4.7 0.1 0.0 7.7 0.0 2.4 0.6 5.2 1.6 0.0 7.6 6.0 0.4 0.0 3.0 0.0 3.8 4.4 0.0 2.2 2.7 0.5 5.4 4.1 1.1 0.0 0.0 2.0 2.1 8.1 5.8 0.7 0.2 0.5 0.8 4.5 0.8 0.3 0.9 0.8 0.8 0.0 0.3 0.8 0.2 4.8 7.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.7 0.0 0.7 0.9 0.0 0.0 0.0 0.2 2.3 1.4 0.3 7.4 0.0 0.6 1.8 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.2 0.4 0.8 3.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 2.5 0.1 2.2 0.0 0.1 0.0 0.0 2.1 0.0 3.2 0.4 0.0 0.0 1.1 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.1 0.3 0.0 1.3 0.2 1.2 0.9 1.2 0.0 0.0 0.3 1.5 0.1 0.8 5.8 1.1 0.0 1.4 0.3 0.9 2.1 HOXA5 "HOX1, HOX1C" ENSG00000106004 "Homeobox A5" P20719 7 27141052-27143681 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 80.9;epididymis: 49.0;fallopian tube: 49.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 99.6;Breast myoepithelial cells: 27.2;Proximal tubular cells: 27.1;Squamous epithelial cells: 46.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 51 "medulla oblongata: 38.3;pons: 10.5;spinal cord: 24.6;white matter: 16.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 94.2;HEK 293: 160.4;RPTEC TERT1: 36.2" "Region enriched" "Detected in single" 220 "pons and medulla: 22.0" "Group enriched" "Detected in some" 33 "medulla oblongata: 4.4;spinal cord: 16.3" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (2.43e-1)" "unprognostic (3.98e-3)" "unprognostic (2.99e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.87e-1)" "unprognostic (7.80e-2)" "unprognostic (4.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.02e-2)" "unprognostic (5.54e-2)" "unprognostic (2.31e-1)" "unprognostic (5.47e-2)" "unprognostic (3.00e-2)" "unprognostic (4.37e-2)" "unprognostic (3.26e-2)" "unprognostic (3.47e-3)" "unprognostic (2.00e-1)" 16.8 80.9 0.2 3.0 0.1 3.1 11.6 0.2 0.4 7.1 0.0 18.7 2.7 12.3 49.0 5.2 49.4 0.9 0.2 0.1 0.1 25.5 0.8 19.9 1.8 38.3 0.4 2.9 1.4 3.3 0.0 0.2 10.5 8.6 6.9 0.0 0.0 9.8 6.7 7.8 13.7 6.2 24.6 3.3 11.7 0.6 0.0 0.5 1.1 0.3 0.1 11.8 4.6 16.6 5.7 2.8 0.0 94.2 0.1 0.0 0.4 1.6 1.2 1.7 1.5 1.7 9.7 3.1 13.5 3.0 2.0 7.6 5.3 0.4 1.7 1.4 160.4 2.2 1.2 5.7 0.9 3.6 2.5 10.3 0.5 3.1 5.4 0.0 20.8 5.5 0.4 0.0 3.2 1.7 0.0 1.1 0.0 2.1 2.9 13.4 0.4 0.0 36.2 7.6 10.9 0.1 7.2 0.0 3.6 0.3 1.1 1.3 8.3 0.3 1.2 5.6 3.9 0.0 0.1 3.3 0.7 10.8 10.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.6 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.1 0.1 38.3 0.4 10.5 24.6 0.0 16.6 9.3 0.0 1.1 0.0 0.9 3.4 6.4 0.1 99.6 0.0 17.3 27.2 8.0 0.0 0.0 0.0 0.0 0.0 2.8 17.0 7.9 0.1 0.0 0.9 19.7 8.4 9.0 2.5 0.0 0.0 0.0 11.5 2.6 0.4 0.0 0.0 21.0 0.0 0.6 0.0 0.0 10.8 0.0 2.5 1.5 0.3 0.3 9.2 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 15.5 0.0 1.0 2.2 9.6 27.1 0.1 0.0 0.0 4.5 14.3 0.9 0.7 46.7 2.8 0.1 1.7 0.2 18.8 6.3 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613183-92670131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 31.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020603 Uncertain Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA020603: AB_1851853" "unprognostic (3.51e-2)" "unprognostic (4.66e-2)" "unprognostic (6.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.63e-2)" "unprognostic (2.08e-1)" "unprognostic (4.88e-2)" "unprognostic (3.13e-2)" "unprognostic (4.40e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.26e-9)" "unprognostic (1.28e-2)" "unprognostic (4.23e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.28e-4)" 5.4 6.9 5.2 4.5 5.7 8.5 6.4 7.5 6.4 9.1 3.9 4.1 3.2 5.2 4.8 31.6 5.4 4.6 7.8 6.9 4.7 4.4 5.3 4.7 5.7 5.5 5.1 5.4 3.6 8.5 8.1 5.5 5.7 4.2 4.4 5.7 8.8 2.8 7.6 29.8 4.2 5.4 5.0 5.4 4.6 11.6 5.6 5.9 4.6 6.1 8.7 5.7 15.5 5.6 19.3 10.1 9.2 8.0 11.1 8.2 30.4 13.5 8.5 13.6 7.8 6.3 7.4 11.9 6.6 18.9 12.0 27.1 16.4 18.9 11.3 14.9 10.4 9.8 21.9 9.9 7.8 16.7 11.2 8.1 18.4 16.3 12.7 12.4 10.3 9.8 13.5 14.1 13.6 26.3 9.6 7.7 15.8 21.2 14.9 8.5 9.8 4.9 8.0 11.5 19.1 11.2 10.9 44.9 7.8 8.9 10.6 4.2 19.7 10.0 11.3 28.2 14.4 13.0 16.2 6.5 13.0 7.5 9.9 0.0 1.4 3.4 3.6 1.8 4.1 2.4 3.0 3.1 2.1 2.2 2.3 2.6 2.1 0.8 1.9 2.3 4.6 1.9 5.2 5.7 7.5 6.4 6.9 4.7 5.5 5.1 5.7 5.0 5.6 5.6 6.8 3.2 3.4 10.1 4.8 25.4 6.4 7.6 16.5 7.5 6.0 4.7 0.4 1.5 5.1 1.8 6.2 10.8 4.6 5.0 5.9 6.2 11.0 8.3 5.3 6.8 6.7 6.1 23.8 8.0 13.8 4.1 7.1 10.2 0.0 3.6 10.0 3.1 5.1 15.2 23.7 3.5 6.1 7.5 4.6 33.7 3.1 5.3 3.6 7.5 2.8 4.9 8.2 20.6 23.3 9.1 1.4 3.0 6.0 6.4 2.6 3.6 2.6 4.6 6.6 3.9 3.5 20.0 19.4 25.5 29.5 22.8 6.0 4.4 3.7 10.5 IRX4 ENSG00000113430 "Iroquois homeobox 4" P78413 5 1877413-1887236 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 15.8;heart muscle: 14.3;skin 1: 22.5;vagina: 12.2" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 48.6;Basal squamous epithelial cells: 50.7;Breast myoepithelial cells: 15.6;Prostatic glandular cells: 13.3;Squamous epithelial cells: 26.5;Suprabasal keratinocytes: 20.2" "Group enriched" "Detected in many" 5 "cervical cancer: 5.4;head and neck cancer: 7.3;lung cancer: 1.8;prostate cancer: 6.9;testis cancer: 7.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 41.8;HaCaT: 16.3;HBEC3-KT: 8.1;MCF7: 8.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "medulla oblongata: 1.2;pons: 1.5" HPA064094 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Vesicles" "HPA064094: " "unprognostic (1.00e-2)" "unprognostic (1.00e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (1.35e-2)" "unprognostic (2.77e-1)" "unprognostic (1.53e-1)" "unprognostic (1.35e-1)" "unprognostic (7.52e-2)" "unprognostic (7.54e-2)" "unprognostic (4.26e-1)" "unprognostic (1.70e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 3.2 0.7 0.0 3.7 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 14.3 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.9 0.0 1.2 9.9 0.0 0.0 9.5 0.0 0.6 22.5 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 16.3 0.0 8.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 8.3 1.1 0.1 0.1 4.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 3.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.8 0.7 1.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 48.6 2.8 0.1 50.7 0.0 1.4 15.6 6.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 1.1 26.5 20.2 3.7 0.0 0.0 0.0 1.7 ITPRIP "bA127L20.2, DANGER, KIAA1754" ENSG00000148841 "Inositol 1,4,5-trisphosphate receptor interacting protein" Q8IWB1 10 104309698-104338465 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 203.2" "Cell type enhanced" "Detected in many" "Adipocytes: 98.0;Hepatic stellate cells: 82.1;Squamous epithelial cells: 108.4;Suprabasal keratinocytes: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 103.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043626 Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA043626: AB_10963078" "unprognostic (2.45e-2)" "unprognostic (3.06e-1)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-1)" "unprognostic (7.87e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (9.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (4.00e-2)" "unprognostic (5.37e-3)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-3)" 36.3 13.7 5.7 16.9 5.9 203.2 25.4 5.3 10.5 31.6 15.5 13.6 3.1 16.3 3.7 52.9 15.1 21.2 72.5 5.5 6.6 18.0 13.3 38.5 10.4 8.0 6.3 29.1 9.4 8.0 15.9 26.8 6.4 14.0 5.0 1.7 14.1 9.0 10.1 66.3 8.8 18.2 7.0 12.6 12.3 7.4 8.0 12.8 21.1 10.4 11.9 23.7 43.5 7.7 6.4 16.1 19.2 8.6 32.8 31.4 10.9 35.0 75.9 25.8 32.0 1.2 2.8 11.2 7.7 22.5 51.2 20.7 6.5 17.4 26.6 9.6 7.6 6.6 24.6 4.9 64.3 15.9 12.3 29.2 103.5 53.8 42.8 29.9 48.7 11.4 28.4 21.5 32.0 2.7 3.1 17.0 14.3 2.2 17.9 14.3 9.9 6.8 10.6 2.8 10.7 7.0 6.7 7.8 16.0 11.6 0.6 11.8 82.7 51.9 13.6 34.5 34.5 7.8 9.8 7.3 38.0 27.9 24.8 4.4 9.5 14.0 4.5 5.8 4.5 2.5 2.7 2.6 6.2 2.8 3.2 2.9 30.6 5.0 5.8 4.2 2.3 21.3 5.7 5.9 5.3 10.5 5.5 6.6 8.0 6.3 6.4 7.0 8.0 7.7 98.0 3.2 8.3 1.3 9.0 37.9 15.3 13.2 44.3 0.0 3.0 2.4 7.8 1.5 9.0 3.7 0.0 7.3 37.0 1.7 0.0 3.7 6.3 11.7 10.0 42.5 0.0 8.8 0.6 2.4 22.6 15.5 3.6 46.7 20.3 3.6 82.1 2.3 10.8 0.0 0.4 2.6 2.0 17.2 20.6 1.6 5.0 28.1 8.8 6.5 7.0 3.8 10.3 0.5 0.9 3.0 0.5 5.7 13.6 5.8 0.2 0.5 5.2 0.6 13.1 6.3 14.7 8.1 1.8 108.4 72.7 5.1 23.8 4.4 1.1 20.5 IVL ENSG00000163207 Involucrin P07476 1 152908546-152911886 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 162.3;esophagus: 298.3;salivary gland: 94.5;skin 1: 160.9;vagina: 235.2" "Cell type enhanced" "Detected in some" "Club cells: 10.4;Squamous epithelial cells: 30.8;Suprabasal keratinocytes: 71.0;Urothelial cells: 13.3" "Group enriched" "Detected in many" 5 "cervical cancer: 44.0;head and neck cancer: 145.4;melanoma: 50.9;urothelial cancer: 47.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "HaCaT: 292.9;RT4: 76.9;SK-BR-3: 86.3" "Not detected" "Not detected" "CAB002243, HPA055211" Enhanced Supported "Nuclear bodies,Centrosome,Cytosol" NA NA 4700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Nuclear bodies, Centrosome" "CAB002243: AB_563785, HPA055211: AB_2682739" "unprognostic (3.29e-4)" "unprognostic (1.91e-1)" "unprognostic (2.92e-2)" "unprognostic (2.31e-2)" "unprognostic (7.60e-2)" "unprognostic (2.22e-1)" "unprognostic (4.82e-2)" "unprognostic (3.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.22e-2)" "unprognostic (1.32e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.0 162.3 0.0 0.0 0.0 0.0 18.2 298.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.0 94.5 0.1 0.4 160.9 0.1 0.0 0.0 0.1 0.2 0.1 0.0 3.5 0.1 0.0 36.9 17.4 235.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 6.0 0.0 0.0 0.2 0.0 292.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.9 0.0 0.0 0.0 86.3 0.0 0.2 3.6 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 3.1 3.5 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 1.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.6 0.0 0.0 30.8 71.0 0.0 0.1 0.0 0.0 13.3 JAG1 "AGS, AHD, AWS, CD339, HJ1, JAGL1" ENSG00000101384 "Jagged canonical Notch ligand 1" P78504 20 10637684-10673999 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 211.1;Endometrial ciliated cells: 197.4;Smooth muscle cells: 190.1;Squamous epithelial cells: 343.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 219.2;hTERT-HME1: 131.1;U-251 MG: 187.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010343, HPA021555" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 25000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane" "CAB010343: AB_649685, HPA021555: AB_1851969" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (4.15e-2)" "unprognostic (1.21e-1)" "unprognostic (6.42e-2)" "unprognostic (4.21e-2)" "unprognostic (8.94e-3)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (4.10e-6)" "unprognostic (5.48e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.10e-1)" "unprognostic (1.41e-3)" 44.2 10.1 10.3 13.0 9.5 21.8 30.3 8.4 12.0 44.0 8.9 23.7 13.8 27.3 19.5 52.4 27.0 21.6 20.7 12.8 9.8 21.7 6.2 23.9 8.4 12.4 14.2 20.3 22.0 20.9 8.2 67.9 10.0 25.9 23.0 22.1 15.8 26.7 9.8 57.2 13.6 23.6 9.7 23.3 25.1 4.5 12.1 9.3 19.9 22.8 15.6 28.5 50.0 8.5 4.1 20.6 63.1 78.1 11.8 11.3 2.3 2.4 11.9 3.3 1.8 18.5 11.2 0.7 59.0 2.4 17.7 85.8 9.4 219.2 2.7 0.2 4.5 7.0 2.2 87.9 5.8 28.4 0.5 4.6 63.7 10.6 131.1 12.5 21.1 0.3 0.1 8.8 6.0 0.2 0.0 20.2 18.2 68.7 20.3 5.3 3.9 13.1 29.9 25.6 2.8 2.1 6.3 4.4 26.2 49.8 0.3 3.3 80.5 14.2 9.9 11.8 187.9 3.6 0.6 0.9 9.1 10.3 11.3 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 10.3 9.5 8.4 12.0 12.8 9.8 12.4 14.2 10.0 9.7 12.1 8.5 73.0 41.7 15.4 5.9 1.1 104.6 54.9 76.3 211.1 9.7 13.2 29.1 20.6 30.0 34.4 16.5 43.8 16.9 6.8 64.3 1.9 31.6 5.0 197.4 22.2 102.5 5.3 0.0 6.9 30.4 1.0 41.9 76.0 96.4 7.0 2.7 60.0 1.8 4.2 21.9 9.2 12.8 20.3 5.9 33.9 9.6 21.5 9.1 14.2 22.5 2.8 11.9 2.1 24.6 1.3 97.3 18.3 33.8 4.3 24.5 7.8 2.3 30.2 69.1 85.5 46.7 190.1 0.9 3.2 343.9 106.8 2.2 4.3 107.2 39.1 33.7 KLHL21 KIAA0469 ENSG00000162413 "Kelch like family member 21" Q9UJP4 1 6590724-6614607 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 169.9" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 104.8;Suprabasal keratinocytes: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 21.4;neutrophil: 63.0" "Lineage enriched" "Detected in all" 8 "granulocytes: 63.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051364, HPA059307" Uncertain Supported Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" Centrosome "HPA051364: AB_2681455, HPA059307: " "unprognostic (6.13e-3)" "unprognostic (5.26e-2)" "unprognostic (2.30e-2)" "unprognostic (9.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.39e-2)" "unprognostic (5.77e-3)" "unprognostic (2.28e-1)" "unprognostic (8.52e-2)" "unprognostic (4.85e-2)" "unprognostic (4.02e-1)" "unprognostic (6.33e-3)" "prognostic favorable (1.71e-4)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (9.74e-2)" "unprognostic (4.19e-2)" 30.5 29.5 31.3 12.6 37.3 25.5 24.6 33.6 35.9 27.2 73.1 44.7 6.9 35.3 8.7 36.4 24.2 14.4 53.3 32.1 31.5 28.2 22.2 16.4 9.2 41.0 44.0 28.6 33.3 21.5 30.1 6.9 37.4 31.7 5.0 7.6 33.3 28.3 169.9 37.0 15.9 16.4 30.7 17.2 30.0 15.2 35.5 9.7 18.7 101.3 7.6 46.5 25.0 44.3 25.8 15.1 7.5 24.3 41.5 25.8 19.5 35.5 28.1 23.0 13.7 44.1 16.1 0.9 30.8 21.9 20.7 41.7 16.6 39.2 12.8 54.8 26.8 29.7 27.8 40.3 34.4 17.8 17.5 28.9 13.0 52.3 17.6 21.6 9.9 14.8 33.3 23.1 19.0 8.9 18.4 15.7 13.8 13.1 55.5 28.0 31.3 32.3 13.5 7.8 30.2 7.5 27.8 22.0 62.8 6.5 14.5 21.0 33.3 74.4 9.1 68.9 86.1 26.2 35.2 18.0 72.2 33.1 28.4 8.4 6.2 21.4 7.1 2.6 6.2 4.5 6.6 7.0 3.8 2.6 5.3 5.3 63.0 2.9 2.3 3.4 8.2 6.1 31.3 37.3 33.6 35.9 32.1 31.5 41.0 44.0 37.4 30.7 35.5 44.3 11.6 3.2 5.1 19.6 8.9 71.2 46.9 22.3 63.2 4.1 47.1 44.4 68.3 7.2 10.7 9.2 4.2 5.1 15.6 10.1 7.9 12.0 2.7 19.6 14.9 15.6 3.0 2.1 8.2 12.9 7.0 24.7 31.1 35.3 0.0 6.4 7.1 23.6 5.6 5.0 8.9 5.6 14.2 10.4 30.1 7.6 10.8 17.1 26.6 8.4 7.6 12.2 4.1 6.6 14.1 20.0 7.3 15.1 12.6 43.1 5.3 7.6 14.0 5.9 13.1 32.2 25.2 2.0 10.9 104.8 72.0 6.4 15.3 9.2 5.5 31.3 KLRG2 "CLEC15B, FLJ44186" ENSG00000188883 "Killer cell lectin like receptor G2" A4D1S0 7 139452690-139483673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.0;salivary gland: 4.3;thyroid gland: 4.1" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 5.2;Collecting duct cells: 7.3;Squamous epithelial cells: 14.2;Syncytiotrophoblasts: 7.7" "Cancer enriched" "Detected in many" 11 "testis cancer: 42.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.7;HAP1: 15.7;NTERA-2: 8.2;SCLC-21H: 7.4;SK-BR-3: 31.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018199 Uncertain Uncertain Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA018199: AB_2133260" "unprognostic (2.50e-2)" "unprognostic (3.05e-2)" "unprognostic (9.82e-2)" "unprognostic (5.38e-8)" "unprognostic (2.41e-1)" "unprognostic (1.97e-2)" "unprognostic (3.13e-2)" "prognostic favorable (8.61e-4)" "unprognostic (2.14e-2)" "unprognostic (2.92e-1)" "unprognostic (5.19e-2)" "unprognostic (8.83e-2)" "unprognostic (1.10e-3)" "unprognostic (5.66e-2)" "unprognostic (1.71e-1)" "unprognostic (1.14e-2)" "unprognostic (2.34e-2)" 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.0 0.4 2.5 0.0 2.9 0.0 0.1 0.0 0.0 0.1 2.8 0.3 0.4 0.1 0.1 0.1 0.0 4.3 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.9 4.1 0.1 0.7 0.1 1.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.0 2.0 0.0 0.0 4.3 0.0 0.0 2.2 15.7 0.0 0.0 0.0 3.9 0.0 0.6 0.0 0.1 0.0 0.3 0.0 6.6 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 2.8 2.5 0.0 8.2 0.0 0.1 0.0 0.0 0.0 0.5 0.1 7.4 0.4 2.3 31.9 0.0 6.1 7.1 1.5 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.5 0.8 0.3 5.2 0.0 1.3 1.4 0.5 0.0 0.1 7.3 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.6 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 1.6 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 14.2 1.0 7.7 0.0 0.0 0.3 0.5 KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40925.1;vagina: 13409.3" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 16844.0" "Group enriched" "Detected in many" 5 "cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 93 "A-431: 2462.5;HaCaT: 1626.2" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 680000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141" "unprognostic (1.45e-1)" "unprognostic (6.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (9.30e-5)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.45e-6)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (3.04e-2)" "unprognostic (4.33e-1)" 7.7 7.5 0.0 0.0 0.1 6.8 5.1 0.0 0.0 6884.6 0.0 5.6 0.1 10.2 0.0 40925.1 7.0 8.8 9.2 0.0 0.1 5.6 12.8 6.0 0.3 0.0 0.0 9.9 17.2 0.0 26.9 0.0 0.0 115.2 0.0 0.0 6881.1 3.8 9.8 20.5 8.5 14.2 0.0 7.7 31.3 6.9 0.0 13.6 6.1 0.0 1855.2 924.7 13409.3 0.0 2462.5 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.6 0.8 7.1 0.6 0.0 0.0 1626.2 0.0 0.4 0.0 1.4 0.0 4.5 21.8 0.0 0.0 1.7 1.3 0.0 0.8 0.0 0.0 0.3 0.0 0.0 5.4 1.2 0.0 1.3 0.1 0.1 0.1 14.8 0.3 0.2 1.2 0.3 0.0 10.7 0.0 0.0 1.9 2.0 7.7 0.0 2.3 6.4 5.1 0.0 0.4 0.0 6.6 0.3 6.3 5.8 1.9 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.0 1.1 0.0 0.9 2.8 545.6 17.1 146.8 0.0 2.3 4.6 0.6 1.5 94.5 0.0 0.0 0.1 0.2 0.6 0.0 0.0 1.2 2.7 0.2 11.4 1.2 5.5 0.0 0.0 0.5 12.6 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 8.2 0.0 0.0 3.2 55.9 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.7 286.6 27.1 227.9 0.1 0.1 3.3 0.0 0.0 0.0 16.9 0.2 0.6 16844.0 1.6 0.4 8.8 0.0 0.4 3645.4 KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 419.1;esophagus: 1156.7;skin 1: 1319.5;vagina: 423.3" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 2789.9;Basal squamous epithelial cells: 8290.4;Squamous epithelial cells: 4637.9" "Cancer enhanced" "Detected in many" "cervical cancer: 178.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "HaCaT: 1156.8;hTCEpi: 1001.5" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 480000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Nucleoplasm "HPA023910: AB_1852205, HPA024554: AB_1852207" "prognostic favorable (4.50e-4)" "unprognostic (9.14e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-3)" "unprognostic (3.57e-2)" "unprognostic (8.84e-2)" "unprognostic (6.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (8.65e-3)" "unprognostic (9.91e-3)" "unprognostic (2.09e-1)" "unprognostic (2.24e-11)" "unprognostic (6.91e-3)" "unprognostic (2.62e-1)" "unprognostic (1.33e-5)" "unprognostic (5.35e-2)" 4.7 0.3 0.1 0.2 0.0 0.7 419.1 0.0 0.1 148.2 0.2 1.1 1.5 0.3 2.2 1156.7 32.4 2.8 0.7 0.1 0.0 0.3 0.6 4.3 0.0 0.1 0.1 0.4 1.4 0.0 1.2 0.3 0.1 182.8 1.6 0.0 140.0 4.1 0.7 1319.5 2.3 0.1 0.0 0.3 1.6 8.0 0.1 93.7 0.5 0.0 77.6 9.5 423.3 0.1 56.4 7.4 0.0 0.0 0.0 0.0 0.7 5.3 1.3 0.3 0.2 5.9 20.2 0.0 1.8 0.6 14.0 1156.8 0.0 41.8 0.2 0.6 0.0 0.0 7.7 1.9 0.0 0.1 4.7 0.0 1001.5 2.2 6.9 2.7 3.4 0.0 0.3 0.5 0.2 3.5 0.1 0.5 0.0 3.9 6.2 0.0 0.0 104.9 3.3 5.9 2.6 0.1 1.1 15.0 1.2 0.3 20.3 0.0 18.6 0.3 2.8 0.3 2.2 0.1 0.1 0.0 8.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 6.1 12.8 10.3 0.0 2.7 1309.8 2789.9 1190.9 8290.4 0.6 577.7 670.3 0.8 5.7 287.5 1.8 0.0 0.7 16.9 18.3 1.9 8.5 117.6 4.1 0.7 22.9 4.8 0.0 0.1 7.5 7.7 21.7 4.6 8.2 2.5 0.0 0.0 0.0 0.4 0.0 0.1 10.3 189.2 0.0 61.7 44.4 1.5 17.2 320.2 0.0 0.0 0.2 0.0 0.0 0.1 14.1 10.5 0.4 88.7 872.9 8.6 0.1 57.7 0.6 0.0 0.4 32.1 0.6 0.8 4637.9 193.6 1.2 21.6 0.1 7.2 906.0 KRT3 "CK3, K3" ENSG00000186442 "Keratin 3" P12035 12 52789685-52796117 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 3.0;salivary gland: 10.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.7;head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 9.4;HMC-1: 5.6" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" NA NA 280000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (2.42e-2)" "unprognostic (2.75e-1)" "unprognostic (9.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (3.89e-2)" "unprognostic (2.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.73e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.3 0.8 0.0 0.0 0.0 0.0 KRT31 "Ha-1, KRTHA1" ENSG00000094796 "Keratin 31" Q15323 17 41393721-41397608 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 284.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 39.1;Basal squamous epithelial cells: 21.6;Endometrial ciliated cells: 7.2;Glandular and luminal cells: 10.9;Squamous epithelial cells: 16.5;Suprabasal keratinocytes: 7.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049550, HPA055194" Enhanced NA NA 440000000 "Cluster 61: Skin - Cornification" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA049550: AB_2680813, HPA055194: AB_2682733" "unprognostic (3.92e-2)" "unprognostic (3.50e-1)" "unprognostic (3.30e-1)" "unprognostic (5.51e-2)" "unprognostic (7.71e-2)" "unprognostic (4.60e-1)" "unprognostic (6.98e-2)" "unprognostic (1.84e-1)" "unprognostic (4.07e-1)" "unprognostic (4.26e-2)" "unprognostic (1.65e-1)" 3.8 0.0 0.4 0.0 0.1 0.0 0.5 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 4.7 284.4 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 39.1 0.3 2.9 21.6 0.0 0.2 0.6 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.0 10.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.4 16.5 7.7 0.0 0.1 0.2 0.0 0.0 KRT32 "Ha-2, KRTHA2" ENSG00000108759 "Keratin 32" Q14532 17 41459513-41467386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.9;skin 1: 19.5" "Group enriched" "Detected in some" 6 "Basal squamous epithelial cells: 21.6;Squamous epithelial cells: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-RPE1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 210000000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.39e-2)" "unprognostic (3.29e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "unprognostic (2.32e-2)" "unprognostic (2.67e-3)" "unprognostic (2.72e-9)" "unprognostic (1.31e-2)" "unprognostic (1.77e-1)" 0.6 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.8 21.6 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.4 0.0 0.4 KRT33A "Ha-3I, Krt1-3, KRTHA3A" ENSG00000006059 "Keratin 33A" O76009 17 41346092-41350828 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 47.5" "Group enriched" "Detected in some" 8 "Basal squamous epithelial cells: 1.8;Early spermatids: 2.2;Late spermatids: 2.1;Squamous epithelial cells: 4.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055194 Supported NA NA 160000000 "Cluster 61: Skin - Cornification" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA055194: AB_2682733" "unprognostic (1.93e-1)" "unprognostic (1.30e-2)" "unprognostic (4.58e-2)" "unprognostic (4.34e-1)" "unprognostic (2.16e-1)" 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 47.5 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 KRT36 KRTHA6 ENSG00000126337 "Keratin 36" O76013 17 41486136-41492546 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 3.5;skin 1: 1.7" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;Late spermatids: 2.1;Prostatic glandular cells: 1.0;Spermatogonia: 2.4;Squamous epithelial cells: 2.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "Karpas-707: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA 180000000 "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (4.39e-2)" "unprognostic (2.24e-3)" "unprognostic (9.85e-2)" "unprognostic (4.66e-1)" "unprognostic (1.70e-2)" "unprognostic (3.19e-2)" "unprognostic (1.34e-1)" "unprognostic (5.36e-2)" "unprognostic (2.25e-1)" "unprognostic (1.81e-1)" "unprognostic (7.19e-2)" "unprognostic (8.24e-2)" "unprognostic (8.50e-2)" "unprognostic (3.74e-1)" "unprognostic (6.66e-2)" "unprognostic (1.49e-1)" "unprognostic (7.11e-2)" 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.0 0.4 0.0 0.2 0.1 3.5 0.0 0.0 1.7 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.3 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.3 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.8 0.0 2.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.4 2.0 0.0 0.0 0.0 0.1 0.2 0.9 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT5 "EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 5865.0;skin 1: 5885.4;vagina: 2150.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5870.1;Basal prostatic cells: 1037.6;Basal squamous epithelial cells: 1571.3;Squamous epithelial cells: 4370.9;Suprabasal keratinocytes: 2020.2" "Group enriched" "Detected in many" 4 "cervical cancer: 1863.2;head and neck cancer: 3340.4" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 326 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 326 "dendritic cells: 32.6" "Group enriched" "Detected in some" 7 "HaCaT: 3368.0;HBEC3-KT: 5990.5;hTCEpi: 13326.8" "Region enriched" "Detected in many" 8 "spinal cord: 36.4" "CAB000027, CAB000129, HPA059479" Enhanced Approved "Intermediate filaments" NA NA 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000027: AB_2281083, CAB000129: , HPA059479: AB_2684034" "prognostic favorable (1.27e-4)" "unprognostic (9.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (1.73e-1)" "unprognostic (6.01e-7)" "unprognostic (3.46e-2)" "unprognostic (5.56e-2)" "unprognostic (7.96e-2)" "unprognostic (2.81e-3)" 10.0 1.7 0.2 1.8 0.8 4.6 252.5 0.7 0.5 826.2 58.9 1.9 0.0 2.0 97.2 5865.0 12.5 2.0 3.8 1.7 0.0 1.3 3.5 6.4 3.0 0.1 0.0 2.2 4.7 0.1 8.2 2.0 0.1 125.8 0.0 0.0 880.3 100.0 9.9 5885.4 1.8 0.6 0.1 1.7 5.0 2.1 0.6 527.1 3.0 0.3 648.6 93.2 2150.9 0.4 50.6 0.0 0.0 0.0 2.3 0.2 0.8 0.0 0.0 0.0 0.0 1.0 0.3 2.4 0.5 0.2 0.0 3368.0 0.2 5990.5 0.2 0.0 0.0 0.2 0.1 0.0 0.6 1.4 2.8 0.3 13326.8 0.6 1049.7 0.0 0.8 0.0 1.8 4.0 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.2 1.0 1.2 0.8 0.9 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.5 0.2 10.1 1.0 0.9 4.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.1 0.2 0.8 0.7 0.5 1.7 0.0 0.1 0.0 0.1 0.1 0.6 0.4 1.7 0.0 1.1 0.0 0.4 5870.1 1037.6 627.1 1571.3 0.0 43.6 226.2 0.5 0.0 180.7 0.0 0.0 0.0 39.8 0.0 0.0 0.5 0.8 31.3 1.2 26.4 0.0 0.0 0.5 0.0 0.0 29.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 273.6 0.1 0.6 7.3 286.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 22.2 789.7 0.0 0.1 34.8 0.0 0.0 0.2 33.4 0.0 0.0 4370.9 2020.2 0.0 17.8 0.0 0.1 459.8 KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 674.0;Club cells: 200.5;Squamous epithelial cells: 876.0;Suprabasal keratinocytes: 151.4;Urothelial cells: 306.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "hTCEpi: 9761.7" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" 3.1 1.5 0.0 1.9 0.0 0.1 6.9 0.0 0.0 2523.3 0.0 1.2 0.0 1.3 0.0 7338.5 9.1 0.9 1.8 0.0 0.0 1.1 2.6 3.4 0.0 0.0 0.0 2.3 3.3 0.0 3.1 8.8 0.0 5.0 0.0 0.0 1025.5 0.0 1.9 480.0 1.3 0.4 0.0 1.4 4.9 1.0 0.0 33.6 1.5 0.0 628.6 19.7 4945.4 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 3.9 0.0 0.0 1143.8 0.0 2414.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.5 0.6 0.3 9761.7 0.2 306.7 0.0 0.3 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 14.0 0.3 0.1 0.5 0.0 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.2 0.2 0.4 0.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.5 79.0 674.0 12.0 0.0 0.6 1.7 0.0 0.0 200.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 2.6 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 5.5 0.0 0.0 0.7 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 100.4 0.0 0.0 24.5 0.0 0.0 0.0 11.8 0.0 0.0 876.0 151.4 0.0 1.7 0.0 0.1 306.8 KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 228.2;esophagus: 934.5;skin 1: 285.1;vagina: 229.6" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 217.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 1424.3;melanoma: 472.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 148.7" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000130: , HPA045697: AB_2679422, HPA061168: AB_2684440" "prognostic favorable (9.44e-4)" "unprognostic (3.27e-2)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (2.07e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (5.77e-2)" "unprognostic (9.63e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (9.52e-4)" 0.9 0.2 0.0 2.0 0.0 0.1 16.2 0.0 0.0 228.2 0.0 0.5 0.0 0.1 0.0 934.5 0.2 0.2 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 168.6 0.0 0.3 285.1 0.2 0.0 0.0 0.1 0.7 0.2 0.0 2.1 0.1 0.0 74.3 0.2 229.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 27.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.7 1.1 0.0 0.1 13.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 20.6 1.8 40.4 0.0 0.0 28.7 16.8 0.1 0.0 16.3 0.0 0.0 0.0 0.9 0.3 0.0 46.2 1.8 0.0 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 1.7 1.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.6 0.0 0.0 2.8 0.0 0.0 0.0 1.4 0.0 0.2 217.5 32.7 0.0 0.3 0.0 0.6 5.9 KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 211.7;esophagus: 799.4;vagina: 333.5" "Cell type enriched" "Detected in some" 60 "Squamous epithelial cells: 234.3" "Group enriched" "Detected in many" 5 "head and neck cancer: 564.7;melanoma: 242.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 94.1" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (3.18e-2)" "unprognostic (6.26e-3)" "unprognostic (6.63e-2)" "unprognostic (1.54e-3)" "unprognostic (6.97e-2)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (3.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "unprognostic (4.50e-2)" 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 211.7 0.0 0.1 0.0 0.1 0.0 799.4 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 144.3 0.0 0.1 24.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.0 0.1 0.0 9.5 0.1 333.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 94.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.2 1.3 2.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 234.3 2.4 0.0 0.0 0.0 0.2 3.9 KRT78 K5B ENSG00000170423 "Keratin 78" Q8N1N4 12 52837804-52849092 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "esophagus: 972.7" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.4;Glandular and luminal cells: 1.9;Spermatocytes: 2.1;Spermatogonia: 8.0;Squamous epithelial cells: 6.7;Suprabasal keratinocytes: 4.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "EFO-21: 5.5;RT4: 1.6;SK-BR-3: 3.6;U-87 MG: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA039724 Enhanced NA NA 70000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA039724: AB_10795255" "unprognostic (5.36e-2)" "unprognostic (5.89e-2)" "unprognostic (2.95e-2)" "unprognostic (3.25e-2)" "unprognostic (1.88e-1)" "unprognostic (2.18e-2)" "unprognostic (3.01e-3)" "unprognostic (8.88e-16)" "unprognostic (3.50e-2)" "unprognostic (6.92e-1)" "unprognostic (7.55e-2)" "unprognostic (1.25e-1)" 0.4 0.2 0.0 0.0 0.0 0.1 3.4 0.0 0.5 227.1 0.0 0.1 0.0 0.1 0.0 972.7 0.1 0.9 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.6 0.0 0.7 0.0 0.0 0.1 0.0 0.0 141.7 0.0 0.3 126.7 0.2 0.0 0.0 0.1 1.0 1.5 0.3 0.4 0.3 0.0 134.2 0.4 221.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 5.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 1.6 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.5 0.6 0.0 0.8 2.4 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 8.0 6.7 4.4 0.3 0.0 0.0 0.2 0.5 KRTAP3-2 KAP3.2 ENSG00000212900 "Keratin associated protein 3-2" Q9BYR7 17 40999193-40999906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 107.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.2;Squamous epithelial cells: 4.8;Suprabasal keratinocytes: 1.1;Urothelial cells: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042992 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA042992: AB_2678258" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 107.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.1 0.0 0.0 0.0 0.0 2.6 LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 362.1;skin 1: 215.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 174.7;Ductal cells: 178.0;monocytes: 248.6;Pancreatic endocrine cells: 227.0;Proximal enterocytes: 214.7;Squamous epithelial cells: 265.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 159.9;CAPAN-2: 158.5;HaCaT: 220.4;HBEC3-KT: 190.3;hTCEpi: 181.5;MCF7: 218.3;OE19: 246.5;RT4: 164.7;SK-BR-3: 250.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" 0.5 0.1 0.0 15.9 0.1 0.1 15.8 0.0 0.2 65.4 0.0 67.6 75.6 5.0 11.0 362.1 14.7 50.2 8.4 0.2 0.6 38.6 21.6 10.6 2.9 0.0 0.0 0.4 50.7 2.4 0.7 4.1 0.0 15.7 51.0 0.0 51.9 22.6 5.1 215.4 74.5 2.9 0.0 1.4 66.9 0.3 0.0 6.2 3.5 0.2 47.7 71.4 135.2 0.0 159.9 1.3 0.0 0.3 0.0 0.0 57.0 0.0 0.0 0.1 0.1 127.3 158.5 0.0 8.9 0.0 0.0 220.4 0.0 190.3 0.1 0.2 0.0 0.0 0.1 79.3 0.0 0.1 0.2 0.1 181.5 0.1 36.8 0.0 0.1 0.0 0.1 0.7 0.1 218.3 0.2 0.4 3.7 246.5 2.6 0.2 7.4 2.3 126.0 164.7 9.1 0.2 0.1 250.6 3.1 5.4 37.6 0.4 0.0 0.1 0.5 0.5 0.6 0.1 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 35.4 0.0 0.9 88.5 112.1 47.2 46.7 0.0 15.4 14.1 2.1 110.1 31.3 31.3 0.0 3.8 0.5 174.7 45.0 178.0 1.1 26.2 2.6 1.6 18.1 0.0 0.0 121.9 5.9 2.6 85.1 34.5 0.0 0.0 0.4 9.0 0.5 0.0 0.0 53.8 18.3 0.6 16.0 3.6 0.0 2.6 10.6 0.0 248.6 0.0 0.0 0.0 0.0 227.0 109.6 0.4 2.9 77.1 214.7 71.8 4.8 0.0 0.0 0.0 3.2 0.0 0.3 265.6 152.7 10.4 1.5 0.0 136.2 150.2 LGALS7 "GAL7, LGALS7A, PIG1, TP53I1" ENSG00000205076 "Galectin 7" P47929 19 38770971-38773492 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 393.1;skin 1: 877.2" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 275.1;Squamous epithelial cells: 639.7;Suprabasal keratinocytes: 725.7" "Group enriched" "Detected in many" 7 "cervical cancer: 32.0;head and neck cancer: 64.8;melanoma: 27.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 7.1;OE19: 2.2" "Low region specificity" "Detected in single" "HPA001549, CAB032606" Enhanced "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB032606: AB_640852, HPA001549: AB_1078938" "unprognostic (1.56e-2)" "unprognostic (1.30e-2)" "unprognostic (1.18e-2)" "unprognostic (4.86e-2)" "unprognostic (2.39e-1)" "unprognostic (2.38e-1)" "unprognostic (2.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.01e-2)" "unprognostic (3.37e-1)" "unprognostic (1.93e-1)" "unprognostic (3.31e-2)" "unprognostic (3.09e-2)" 1.0 0.2 0.0 0.0 0.0 0.0 13.6 0.0 0.0 63.2 0.0 0.3 0.0 0.4 0.0 393.1 0.4 0.2 0.5 0.0 0.1 0.7 0.3 0.4 0.0 0.1 0.1 0.3 0.4 0.0 0.4 0.0 0.1 2.0 0.0 0.0 25.5 0.2 10.7 877.2 0.2 0.0 0.0 2.3 0.5 1.5 0.0 0.5 0.7 0.4 2.2 0.3 155.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 275.1 0.9 124.3 89.4 0.0 0.3 2.8 0.2 0.0 57.6 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 7.5 1.1 0.0 0.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 1.6 0.0 0.4 10.7 0.0 0.0 1.7 3.8 1.5 0.8 639.7 725.7 0.0 0.5 0.1 0.0 1.5 LONRF1 "FLJ23749, RNF191" ENSG00000154359 "LON peptidase N-terminal domain and ring finger 1" Q17RB8 8 12721906-12756073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023584, HPA024814" Uncertain Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Centrosome "HPA023584: AB_1853233, HPA024814: AB_1853235" "unprognostic (2.59e-1)" "unprognostic (2.17e-3)" "unprognostic (1.35e-2)" "unprognostic (3.56e-1)" "unprognostic (9.09e-2)" "unprognostic (3.96e-3)" "unprognostic (3.13e-1)" "unprognostic (5.78e-2)" "unprognostic (2.74e-3)" "unprognostic (1.18e-1)" "unprognostic (5.83e-2)" "unprognostic (3.39e-1)" "unprognostic (5.46e-3)" "unprognostic (8.97e-2)" "unprognostic (8.90e-2)" "unprognostic (3.08e-3)" "unprognostic (1.15e-1)" 16.2 5.8 2.8 4.5 2.7 5.9 10.5 3.4 3.7 11.4 1.3 7.7 2.3 11.3 9.6 13.0 10.5 9.5 4.9 3.0 2.3 6.3 9.9 7.3 7.1 2.2 2.1 15.2 7.5 8.0 3.8 10.1 1.9 10.7 4.3 7.9 8.0 10.6 17.2 28.7 4.5 9.2 2.3 8.4 5.4 15.8 2.6 6.8 8.7 11.3 8.1 7.9 8.3 3.0 1.2 3.0 15.0 4.6 15.6 7.4 10.0 3.8 6.3 4.1 5.7 0.9 3.9 24.0 0.9 6.7 12.9 1.8 12.0 4.7 4.6 3.7 6.8 7.9 0.5 6.2 14.4 2.1 3.0 7.0 8.2 2.6 8.9 3.8 6.4 9.7 1.1 56.6 2.7 4.2 10.4 7.0 15.5 4.8 0.9 5.8 10.2 4.3 3.5 10.2 31.2 3.6 2.2 5.1 29.8 10.7 1.0 10.4 2.9 2.2 3.7 8.9 3.0 4.3 20.7 12.4 12.0 7.2 7.0 0.0 0.1 0.6 0.1 0.5 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 2.8 2.7 3.4 3.7 3.0 2.3 2.2 2.1 1.9 2.3 2.6 3.0 18.9 9.6 16.3 23.2 25.2 60.8 32.8 7.8 52.3 25.1 15.1 10.3 9.7 10.0 13.1 11.0 16.7 3.6 6.3 4.3 7.9 5.3 57.4 12.1 27.9 15.1 2.4 4.6 67.0 4.0 8.2 24.2 5.6 28.3 6.3 27.8 6.1 14.7 5.6 8.4 43.6 6.4 4.1 9.5 27.6 53.5 29.2 17.2 44.4 21.5 3.6 8.3 0.0 42.7 14.9 4.3 6.4 19.9 16.3 26.4 3.8 6.0 8.7 13.0 19.7 36.7 32.7 8.2 19.7 26.4 73.6 7.3 9.7 3.4 5.8 30.1 LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.3;intermediate monocyte: 66.3;myeloid DC: 49.8;neutrophil: 45.0;non-classical monocyte: 50.1" "Group enriched" "Detected in many" 36 "dendritic cells: 49.8;granulocytes: 45.0;monocytes: 71.3" "Cell line enhanced" "Detected in many" "HHSteC: 393.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus" "CAB026202: , HPA061617: AB_2732666" "unprognostic (2.60e-2)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" "unprognostic (3.24e-3)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (3.66e-2)" "unprognostic (9.84e-3)" "unprognostic (6.91e-2)" "unprognostic (2.86e-1)" 67.6 64.4 13.9 36.4 14.6 11.7 60.3 14.7 15.9 65.8 18.0 72.7 48.6 68.1 20.7 81.3 49.6 48.3 37.2 13.3 15.8 55.1 135.8 66.0 14.6 19.6 17.3 46.3 78.7 54.9 26.3 48.6 18.8 61.9 34.3 1.9 61.5 44.0 26.3 75.1 51.1 62.6 17.4 44.8 67.7 13.3 18.1 11.7 57.2 23.5 18.0 65.8 65.1 17.0 98.2 130.3 0.0 41.1 245.9 183.7 89.9 67.9 153.1 98.8 101.1 62.0 148.7 0.1 39.5 145.7 0.5 112.2 0.5 140.5 38.9 0.0 0.2 58.1 53.2 36.6 393.1 4.1 94.6 270.8 255.2 70.7 197.1 102.6 91.2 0.0 55.5 0.5 115.0 93.5 0.4 29.3 1.2 155.7 74.4 0.0 6.6 0.2 149.2 112.2 0.7 0.5 63.6 122.9 143.6 5.0 20.5 105.3 58.0 34.6 39.6 129.0 72.1 0.0 0.4 0.1 14.6 35.9 129.5 5.4 71.3 0.5 0.2 66.3 0.0 0.1 0.1 0.1 49.8 0.1 0.3 0.2 45.0 1.5 50.1 11.8 0.1 27.2 13.9 14.6 14.7 15.9 13.3 15.8 19.6 17.3 18.8 17.4 18.1 17.0 47.0 60.9 68.9 2.9 3.6 39.0 87.2 46.4 72.3 4.1 33.9 35.9 15.5 45.8 60.7 31.3 0.0 31.3 12.4 78.3 9.8 52.2 0.7 23.8 48.6 49.3 52.0 15.8 0.5 99.8 43.6 50.5 89.7 45.2 29.7 30.1 50.7 66.5 48.7 0.0 0.5 57.1 34.6 77.3 34.6 5.1 52.8 50.8 23.2 14.0 43.1 9.6 11.3 5.5 1.1 69.5 82.3 39.9 3.3 110.7 136.9 30.1 42.8 1.6 26.3 33.1 42.0 1.6 0.9 78.9 61.7 37.5 4.9 28.0 63.4 97.6 LY6D E48 ENSG00000167656 "Lymphocyte antigen 6 family member D" Q14210 8 142784882-142786539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2074.3;skin 1: 850.4;vagina: 491.2" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 1171.6;Squamous epithelial cells: 1913.0;Suprabasal keratinocytes: 3866.1" "Group enriched" "Detected in many" 7 "cervical cancer: 409.8;head and neck cancer: 444.6;urothelial cancer: 242.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "A-431: 162.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024755, HPA064317" Enhanced NA NA 210000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA024755: AB_1853410, HPA064317: AB_2685244" "unprognostic (2.13e-2)" "unprognostic (7.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-2)" "unprognostic (8.97e-2)" "unprognostic (1.51e-2)" "unprognostic (3.84e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (8.68e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.50e-1)" "unprognostic (3.97e-1)" "unprognostic (5.40e-4)" "unprognostic (1.06e-1)" 1.7 47.6 0.6 0.2 0.6 0.0 20.4 0.5 1.4 297.4 0.5 0.9 0.0 0.3 0.0 2074.3 1.0 1.4 0.8 0.6 0.5 0.3 0.8 0.5 0.0 0.5 0.5 0.5 1.0 0.0 1.0 2.5 0.5 15.3 0.2 0.0 235.4 0.3 2.6 850.4 0.5 0.0 0.5 0.5 12.4 0.4 0.5 4.6 0.4 0.0 75.6 65.2 491.2 0.7 162.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 6.0 0.0 1.3 0.0 0.2 0.0 0.0 4.0 11.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 1.2 4.0 0.2 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.4 0.6 0.5 0.5 0.5 0.5 0.5 0.5 0.7 0.1 3.2 0.0 0.0 0.0 1171.6 9.4 244.9 138.3 0.0 14.8 14.1 0.2 0.0 154.0 1.8 0.0 0.9 0.1 0.4 1.9 1.1 0.0 0.4 0.1 10.7 0.0 0.0 0.3 0.2 5.7 9.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 22.4 0.0 137.3 0.0 0.0 0.8 163.7 0.0 0.0 0.0 0.0 0.0 0.1 7.0 0.0 0.0 2.5 18.9 0.0 1.2 12.2 0.0 0.0 0.6 16.1 0.0 0.0 1913.0 3866.1 8.2 4.0 0.0 0.4 164.6 LY6G6D "C6orf23, G6D, Ly6-D, MEGT1, NG25" ENSG00000244355 "Lymphocyte antigen 6 family member G6D" O95868 6 31715356-31717804 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 24.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "colorectal cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEL: 1.7" "Region enhanced" "Detected in many" "cerebellum: 6.1" HPA054412 Uncertain "Intracellular and membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 36: HEL - Hemostasis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA054412: AB_2682480" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (2.13e-1)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 3.9 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.1 0.0 0.0 1.4 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1066.8;skin 1: 669.3;vagina: 487.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 504.7;Squamous epithelial cells: 811.7;Suprabasal keratinocytes: 2306.1;Syncytiotrophoblasts: 715.8;Urothelial cells: 642.9" "Cancer enhanced" "Detected in many" "cervical cancer: 158.5;head and neck cancer: 235.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5;HaCaT: 99.5;MCF7: 114.2;RT4: 108.2;SK-BR-3: 158.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 7600000 "Cluster 32: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Vesicles" "HPA041529: AB_2677534, HPA041797: AB_2677679, HPA077859: " "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (1.07e-3)" "unprognostic (5.13e-2)" "unprognostic (8.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-3)" 1.7 3.5 0.7 1.7 0.8 6.6 32.1 0.6 1.0 259.1 1.4 1.1 0.5 7.6 1.8 1066.8 3.5 1.3 1.3 0.7 0.9 2.9 1.2 1.6 2.6 0.7 0.8 8.9 1.3 1.8 2.3 12.3 0.7 11.9 0.7 1.0 183.3 1.3 2.8 669.3 1.6 0.8 0.7 2.1 3.3 1.1 0.8 12.2 1.2 0.2 131.9 55.0 487.0 0.7 38.6 0.6 0.2 0.6 0.3 0.0 15.3 1.5 3.9 1.4 1.9 0.5 42.5 0.4 1.7 1.1 5.6 99.5 0.2 4.4 0.7 0.0 0.3 0.7 4.5 0.8 0.4 0.0 0.9 1.7 37.2 0.2 0.3 1.7 0.0 3.1 0.2 0.1 0.1 114.2 0.9 0.0 0.2 24.3 8.3 0.5 0.0 0.2 1.0 108.2 0.1 0.3 0.5 158.9 1.8 4.7 17.7 0.1 0.0 0.0 0.7 0.5 0.7 0.6 3.0 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.8 0.0 1.1 0.1 2.9 1.1 2.6 0.0 5.5 4.7 2.1 0.0 0.0 0.3 0.9 1.2 0.7 0.8 0.6 1.0 0.7 0.9 0.7 0.8 0.7 0.7 0.8 0.7 0.9 0.0 1.1 0.0 1.3 504.7 102.5 161.2 111.0 0.7 66.6 38.0 0.6 2.8 72.6 14.7 0.0 96.5 2.1 0.9 1.9 1.6 0.1 4.5 4.4 7.5 0.0 0.4 0.0 0.2 87.2 18.1 3.6 24.5 5.7 0.5 0.0 0.3 14.0 3.3 0.1 2.2 24.4 0.3 139.8 0.0 0.6 23.2 147.7 0.0 0.7 4.5 0.0 0.0 0.2 4.7 0.2 0.4 0.0 40.4 0.3 0.7 5.7 0.5 0.0 1.5 10.5 0.1 0.9 811.7 2306.1 715.8 9.6 0.5 1.1 642.9 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 17 "Squamous epithelial cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-138 MG: 1.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 MINK1 "B55, MAP4K6, MINK, YSK2, ZC3" ENSG00000141503 "Misshapen like kinase 1" Q8N4C8 17 4833340-4898061 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056296 Approved NA NA 26000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA056296: AB_2683090" "unprognostic (2.80e-1)" "unprognostic (3.83e-2)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.88e-1)" "unprognostic (3.26e-3)" "prognostic unfavorable (3.00e-4)" "unprognostic (4.64e-3)" "unprognostic (3.21e-1)" "unprognostic (2.78e-2)" "prognostic favorable (2.77e-4)" "prognostic unfavorable (9.27e-4)" "unprognostic (8.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.47e-2)" "unprognostic (1.62e-1)" 22.8 21.5 32.4 24.9 29.8 22.7 24.7 13.0 34.4 32.0 0.0 36.9 43.0 19.1 5.7 72.1 21.3 18.6 15.4 50.7 15.1 23.0 17.5 35.6 23.9 17.7 16.2 36.9 29.4 23.2 25.7 23.2 15.3 25.5 28.1 18.2 32.4 12.2 12.5 76.9 41.7 14.6 13.4 27.6 29.0 14.2 26.4 16.8 21.9 9.9 18.8 21.8 46.6 20.2 46.9 83.6 20.2 31.2 29.7 21.8 56.0 37.4 34.2 27.6 24.7 32.3 31.3 34.5 41.5 38.2 30.0 91.8 15.5 64.2 20.2 49.0 41.2 23.9 62.8 25.3 18.8 9.1 45.2 22.4 44.1 27.1 25.2 24.9 30.8 10.8 25.6 27.4 22.9 27.8 14.8 20.2 15.6 30.4 28.4 17.9 16.9 20.4 42.2 53.9 20.9 16.6 40.1 30.7 23.9 24.2 27.7 12.2 45.0 29.6 13.7 52.8 35.6 16.8 14.6 7.3 26.7 19.2 20.5 0.0 0.7 2.9 1.0 0.6 1.2 1.1 1.1 0.8 0.5 0.7 0.7 0.3 0.6 0.1 0.3 0.3 1.3 1.2 32.4 29.8 13.0 34.4 50.7 15.1 17.7 16.2 15.3 13.4 26.4 20.2 18.1 0.0 2.0 51.9 12.7 41.0 14.7 22.0 37.5 7.2 17.3 18.8 1.4 22.8 9.9 5.5 39.6 18.9 10.2 47.3 5.9 9.5 3.6 10.6 8.6 15.4 18.7 13.0 25.5 10.5 13.3 8.5 51.0 12.7 8.2 21.1 16.1 9.8 18.3 13.5 24.7 30.3 16.2 12.3 16.7 6.8 16.1 13.9 16.0 37.5 29.5 6.9 9.2 13.0 48.1 14.8 46.7 14.7 9.7 19.9 29.3 13.0 12.8 16.9 13.1 6.9 7.6 5.8 13.8 40.9 60.5 19.6 15.9 28.3 27.4 20.1 MSGN1 pMesogenin1 ENSG00000151379 "Mesogenin 1" A6NI15 2 17816460-17817798 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 26 "Basal squamous epithelial cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (3.63e-2)" "unprognostic (3.25e-2)" "unprognostic (1.66e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 MUC21 "bCX31G15.2, C6orf205" ENSG00000204544 "Mucin 21, cell surface associated" Q5SSG8 6 30983718-30989903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 135.8;esophagus: 696.3;vagina: 244.5" "Group enriched" "Detected in some" 5 "Club cells: 11.8;Squamous epithelial cells: 37.7;Urothelial cells: 32.0" "Group enriched" "Detected in many" 9 "cervical cancer: 6.8;head and neck cancer: 6.6;lung cancer: 13.9;stomach cancer: 7.0;thyroid cancer: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052028 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA052028: AB_2681700" "unprognostic (2.27e-2)" "unprognostic (4.85e-3)" "unprognostic (5.24e-3)" "unprognostic (1.68e-2)" "unprognostic (2.68e-2)" "unprognostic (2.98e-3)" "unprognostic (1.32e-4)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" "unprognostic (3.24e-2)" "unprognostic (7.81e-2)" 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 135.8 0.0 0.1 0.0 0.1 0.0 696.3 0.2 0.0 0.1 0.0 0.0 0.1 0.3 1.3 0.0 0.0 0.0 0.2 0.4 0.0 0.6 0.0 0.0 0.3 0.0 0.0 106.8 0.0 0.3 0.2 0.1 0.0 0.0 0.1 1.7 0.1 0.1 0.0 0.1 0.0 13.4 0.2 244.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.2 1.6 0.0 0.0 0.0 0.0 0.2 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.3 0.1 0.0 32.0 MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 254.6;skin 1: 289.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1013.3;Basal prostatic cells: 1080.5;Basal squamous epithelial cells: 1270.8;Squamous epithelial cells: 768.8;Suprabasal keratinocytes: 1070.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 1069.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" 254.6 59.8 2.6 62.3 2.2 53.7 115.8 3.7 3.3 54.4 3.0 57.9 30.6 53.8 3.8 99.5 167.5 83.3 45.5 2.3 6.3 20.0 64.9 47.0 49.4 9.2 5.0 100.0 103.1 7.0 12.3 33.4 6.0 32.7 36.8 0.7 42.2 14.1 50.6 289.1 48.6 54.8 4.5 60.1 70.6 12.5 5.5 47.2 27.0 15.7 39.2 63.2 96.3 4.4 56.8 89.3 9.3 100.9 166.6 209.8 28.4 72.2 31.6 87.5 72.7 137.0 150.2 587.3 86.4 43.0 82.4 122.2 383.8 226.5 67.8 128.9 167.0 370.7 189.5 203.6 150.0 282.0 52.0 138.8 560.4 55.5 490.8 74.8 104.3 217.3 549.8 315.5 49.7 151.9 394.4 616.9 27.4 273.2 204.0 203.7 46.1 1069.6 79.2 61.9 660.7 64.9 32.6 270.7 195.9 17.5 106.4 172.2 120.5 63.4 71.6 49.7 87.2 5.5 8.7 275.9 55.3 286.2 30.8 3.0 39.5 0.7 31.5 36.0 161.5 92.0 114.3 67.4 33.5 71.4 195.2 128.0 4.1 85.5 26.9 1.4 95.6 88.9 2.6 2.2 3.7 3.3 2.3 6.3 9.2 5.0 6.0 4.5 5.5 4.4 218.0 57.7 70.4 0.7 108.0 1013.3 1080.5 278.9 1270.8 0.6 251.3 207.3 10.9 44.3 98.4 12.9 0.0 20.6 20.9 23.0 1.9 78.3 1.0 43.9 224.5 158.0 12.5 189.1 1.6 43.6 61.2 337.9 46.4 72.0 57.0 47.6 141.0 25.8 26.9 0.0 1.1 67.8 97.6 43.7 133.1 3.9 98.8 23.3 168.9 1.0 17.0 1.4 5.2 0.0 0.2 66.5 40.4 67.4 45.7 364.8 4.8 13.3 21.5 0.3 46.0 458.5 349.1 0.6 0.6 768.8 1070.1 5.9 75.0 56.0 117.7 409.4 MYCL "bHLHe38, LMYC, MYCL1" ENSG00000116990 "MYCL proto-oncogene, bHLH transcription factor" P12524 1 39895426-39902256 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 67.8;skin 1: 41.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.9;Hepatocytes: 24.3;Intestinal goblet cells: 25.0;monocytes: 27.4;Squamous epithelial cells: 34.2;Urothelial cells: 27.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 28.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8" "Group enriched" "Detected in many" 72 "dendritic cells: 22.8;monocytes: 17.3" "Group enriched" "Detected in many" 7 "U-266/70: 444.0;U-266/84: 364.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA063132, HPA074515" Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Mitotic chromosome" "HPA063132: AB_2684946, HPA074515: " "unprognostic (7.45e-2)" "unprognostic (6.91e-2)" "unprognostic (7.36e-2)" "unprognostic (1.83e-3)" "unprognostic (1.61e-2)" "unprognostic (2.92e-3)" "unprognostic (6.72e-3)" "prognostic favorable (4.49e-4)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-3)" "unprognostic (2.75e-2)" "unprognostic (5.21e-2)" "unprognostic (1.53e-2)" "unprognostic (5.80e-2)" 0.8 0.3 1.8 4.7 2.0 0.6 3.3 1.2 2.0 5.2 1.8 6.1 4.8 0.9 7.2 22.1 3.1 1.5 0.5 2.2 1.7 1.5 11.4 3.3 6.4 1.5 1.5 0.3 67.8 0.3 2.9 6.7 1.6 4.2 6.7 0.2 6.4 7.5 0.5 41.5 5.7 1.1 1.9 7.6 6.2 1.3 2.0 6.5 5.3 0.5 9.5 15.9 12.8 1.6 1.2 0.4 14.4 3.5 0.2 0.1 31.8 0.5 0.2 1.0 0.7 0.4 0.8 2.2 1.4 0.1 0.4 3.3 10.4 2.7 0.8 2.0 4.9 0.5 0.3 0.5 0.4 0.3 7.5 1.0 12.1 0.4 1.3 0.2 1.2 5.4 3.2 0.4 0.6 1.2 0.2 0.3 13.4 2.2 0.4 1.3 15.5 2.9 1.1 58.0 2.5 3.1 1.4 2.1 0.8 5.5 3.7 18.7 0.0 0.0 4.6 6.2 0.5 444.0 364.6 1.0 0.1 2.3 0.3 0.0 17.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.2 0.0 3.4 22.8 0.0 6.7 1.8 2.0 1.2 2.0 2.2 1.7 1.5 1.5 1.6 1.9 2.0 1.6 0.4 0.0 1.1 0.0 0.8 6.6 10.0 2.1 13.1 0.4 3.8 6.0 3.7 0.0 5.5 9.2 0.0 34.9 20.1 13.4 0.0 1.5 0.1 5.1 0.6 0.5 17.3 0.0 0.2 5.8 15.4 0.9 5.1 6.3 0.0 0.0 1.4 24.3 5.1 0.0 0.3 25.0 8.2 8.3 13.1 0.4 0.0 10.6 1.8 0.0 27.4 0.8 0.0 1.0 0.0 2.9 6.5 0.0 3.6 5.3 6.4 0.1 4.9 0.1 0.0 1.4 0.7 0.0 1.2 34.2 11.8 17.5 0.3 0.0 10.8 27.1 NCOA7 "dJ187J11.3, ERAP140, TLDC4" ENSG00000111912 "Nuclear receptor coactivator 7" Q8NI08 6 125781161-125932034 "Predicted intracellular proteins, Transporters" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 709.7;Squamous epithelial cells: 515.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030289, HPA030290, HPA030291, HPA030292" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA030289: AB_10670031, HPA030290: AB_10601971, HPA030291: AB_10669597, HPA030292: AB_10670834" "unprognostic (1.01e-2)" "unprognostic (3.21e-2)" "unprognostic (7.32e-3)" "unprognostic (7.27e-3)" "unprognostic (1.54e-1)" "unprognostic (4.67e-2)" "unprognostic (1.26e-1)" "unprognostic (6.27e-2)" "unprognostic (2.73e-1)" "unprognostic (2.14e-1)" "unprognostic (6.08e-2)" "unprognostic (4.37e-2)" "prognostic favorable (1.78e-6)" "unprognostic (2.10e-1)" "unprognostic (2.58e-1)" "unprognostic (1.14e-1)" "unprognostic (8.10e-2)" 53.9 60.4 19.5 45.8 30.6 42.7 27.4 21.4 50.2 29.0 0.0 30.1 33.0 22.3 5.2 30.4 15.9 46.6 16.0 28.2 23.9 56.6 32.9 52.1 30.1 47.5 12.3 14.8 19.9 8.8 29.7 12.9 45.0 18.6 29.2 18.2 38.2 12.9 6.9 11.1 39.2 28.3 10.6 24.4 30.8 7.8 19.0 21.7 25.1 9.2 28.5 101.8 19.7 48.3 13.7 36.6 2.2 16.0 78.2 46.3 23.7 18.2 71.9 22.1 30.1 34.3 12.7 55.2 96.5 10.0 108.0 78.7 12.6 12.4 13.3 120.2 16.5 28.0 43.7 12.3 44.5 16.4 25.4 33.3 29.4 21.1 16.3 39.1 46.7 18.0 38.7 30.6 13.9 13.7 16.1 16.2 2.7 33.8 7.6 12.3 5.7 10.3 39.1 90.4 36.9 33.5 93.7 22.6 42.1 6.5 3.8 19.3 27.7 5.1 10.9 26.3 14.1 39.9 34.1 28.8 11.5 21.2 18.7 17.0 11.4 4.0 19.2 9.1 24.1 17.7 18.1 15.6 10.0 11.1 9.6 9.4 6.4 13.6 14.2 34.1 8.1 5.1 19.5 30.6 21.4 50.2 28.2 23.9 47.5 12.3 45.0 10.6 19.0 48.3 144.6 314.1 371.9 27.7 33.7 98.1 270.8 311.2 709.7 50.2 94.2 47.9 11.4 98.7 324.1 62.5 43.8 9.3 84.6 113.2 80.3 241.7 0.9 160.1 90.2 130.2 35.8 29.8 144.9 139.2 8.9 94.8 142.8 298.2 37.3 18.5 106.7 23.2 13.6 37.0 89.5 119.3 288.9 33.8 57.4 6.8 42.3 41.9 51.6 75.9 33.4 76.8 59.8 34.2 303.9 108.7 160.1 29.3 44.1 129.5 24.3 103.2 335.8 53.3 13.1 33.8 49.3 11.2 33.9 515.9 59.2 3.8 63.5 36.5 130.6 294.4 NKX2-8 "Nkx2-9, NKX2.8, NKX2H" ENSG00000136327 "NK2 homeobox 8" O15522 14 36580004-36582614 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;esophagus: 2.6;testis: 7.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.3;Basal squamous epithelial cells: 6.8;Late spermatids: 2.1;Oligodendrocytes: 2.6;Prostatic glandular cells: 2.1;Squamous epithelial cells: 3.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.6;PC-3: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062879 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Plasma membrane" "HPA062879: AB_2684892" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.37e-3)" "unprognostic (2.27e-1)" "unprognostic (3.45e-4)" "unprognostic (2.36e-1)" "unprognostic (8.34e-2)" "unprognostic (7.80e-2)" "unprognostic (3.66e-1)" "unprognostic (3.11e-1)" "unprognostic (8.39e-3)" "unprognostic (4.60e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" 0.0 0.0 0.4 0.0 1.1 0.0 0.0 1.2 0.5 0.1 0.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.3 0.0 2.3 1.3 0.0 0.0 0.1 1.1 0.0 2.4 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 7.9 2.1 0.0 1.4 0.0 0.0 0.0 0.0 4.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 3.6 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 1.2 0.5 0.2 2.1 2.3 1.3 2.4 2.0 2.1 4.4 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.9 6.8 0.0 1.0 1.1 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 2.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.2 3.4 0.4 0.0 0.0 0.0 0.0 0.4 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 918.0;Gastric mucus-secreting cells: 438.3;Plasma cells: 778.5;Squamous epithelial cells: 1490.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported "Plasma membrane,Midbody ring,Cytosol" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane, Midbody ring" "CAB036213: , CAB036214: , CAB036215: , HPA041113: AB_2677305" "unprognostic (7.21e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 503.5 428.3 308.0 259.5 319.0 329.4 489.1 328.0 379.9 439.2 431.1 409.2 335.1 383.4 236.1 610.6 350.6 187.0 403.9 313.7 338.6 478.1 428.4 339.6 288.9 326.6 320.7 500.1 632.0 201.8 234.9 204.8 321.3 367.7 330.4 63.3 432.4 247.5 545.7 540.3 307.6 286.2 326.8 336.0 403.5 77.8 333.3 190.0 305.3 353.7 289.1 463.5 464.2 333.4 1638.6 2233.9 466.1 913.7 969.3 1399.2 1449.2 1091.7 954.0 1404.8 1053.5 1789.7 792.3 1314.3 1662.9 913.0 706.6 956.2 947.3 1273.3 1035.7 1604.8 3283.2 1120.3 1345.8 2513.4 1116.1 1736.0 760.5 1324.1 1420.0 901.9 1466.4 914.6 860.9 856.5 1541.7 773.7 956.1 2741.9 931.3 2144.8 831.4 2974.6 3364.2 875.9 1731.8 2157.2 1417.9 1800.2 1160.6 641.9 674.1 1472.7 1583.0 806.1 1201.7 1268.5 1013.5 1462.8 1158.2 1135.2 1774.8 1520.9 2176.6 1558.1 815.1 919.1 819.2 66.8 243.4 14.0 166.7 325.5 235.6 338.9 211.9 183.3 439.5 259.2 153.5 170.0 13.8 251.6 282.5 478.1 211.2 298.2 308.0 319.0 328.0 379.9 313.7 338.6 326.6 320.7 321.3 326.8 333.3 333.4 9.7 28.9 67.2 0.0 146.8 14.5 8.3 10.8 918.0 0.9 41.6 35.9 0.0 22.8 85.7 5.5 0.0 10.0 10.1 7.1 37.2 47.4 0.6 16.4 34.3 60.9 14.6 298.2 0.0 34.5 27.8 99.0 438.3 21.3 42.9 6.8 22.9 37.6 16.4 0.0 0.0 19.3 8.2 34.8 17.4 2.1 25.7 136.7 10.6 0.0 55.5 0.4 2.1 0.0 0.0 40.7 15.6 12.8 778.5 7.6 11.7 33.8 63.6 0.8 6.6 10.2 43.3 0.6 5.6 1490.1 14.9 8.8 87.0 6.8 25.0 11.0 NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 38.5;vagina: 30.7" "Group enriched" "Detected in many" 4 "Squamous epithelial cells: 212.4;Suprabasal keratinocytes: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Cell line enhanced" "Detected in many" "Daudi: 90.2;HaCaT: 382.6;K-562: 311.3;Karpas-707: 135.7" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA025926: AB_1854539" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (5.83e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.19e-2)" "unprognostic (7.12e-2)" "unprognostic (7.29e-3)" "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.07e-10)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (2.54e-2)" "unprognostic (5.55e-2)" 0.1 0.3 0.4 0.7 0.5 9.7 1.5 0.6 1.1 12.3 0.0 1.4 0.8 0.1 0.0 100.2 0.2 0.0 0.2 0.3 2.8 0.2 0.0 0.8 0.5 1.1 2.6 0.1 0.1 0.0 2.3 0.8 0.8 0.2 0.8 0.1 14.3 0.2 0.1 38.5 1.4 0.2 3.0 0.1 4.0 2.2 6.8 1.7 2.5 0.0 7.7 0.1 30.7 0.4 41.3 0.3 22.1 5.6 0.0 0.0 0.0 0.0 0.0 2.9 7.8 0.3 61.5 90.2 8.6 0.0 8.5 382.6 46.1 3.3 2.3 5.6 25.1 0.6 36.0 0.0 0.0 0.0 0.3 0.0 4.2 0.0 3.0 10.0 0.4 6.4 311.3 135.7 0.3 9.9 1.2 0.2 11.7 7.5 11.4 0.2 0.0 0.5 1.9 0.4 19.5 49.0 30.9 0.8 0.1 4.2 20.9 0.1 2.7 0.2 27.5 0.3 54.5 39.1 0.3 0.0 18.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.6 1.1 0.3 2.8 1.1 2.6 0.8 3.0 6.8 0.4 0.0 0.0 2.3 0.0 0.6 16.3 0.6 16.2 4.0 0.2 0.9 1.3 0.1 0.0 8.0 0.0 0.0 2.0 0.0 0.6 0.0 0.1 0.4 3.9 0.3 0.7 0.0 14.5 0.2 0.2 0.1 4.4 29.6 5.8 1.3 0.9 0.0 0.1 0.3 0.0 17.2 0.8 20.3 0.0 1.6 0.3 0.0 0.2 3.6 0.0 0.1 2.0 0.0 1.0 0.2 2.4 0.2 0.0 1.2 0.4 0.0 0.0 7.0 0.0 0.0 0.0 1.2 5.8 10.0 212.4 73.6 0.1 0.7 0.2 2.6 12.0 NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 325.5" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 95.5;Suprabasal keratinocytes: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.5;T-cells: 18.5" "Cell line enhanced" "Detected in all" "Karpas-707: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 72.3 53.7 23.5 6.3 27.0 5.4 63.1 52.9 49.7 109.6 10.6 53.3 14.3 35.8 4.5 42.5 27.7 7.1 60.8 24.9 17.2 38.0 43.2 49.2 9.3 18.1 20.9 71.3 24.3 9.0 32.0 6.0 15.9 40.5 4.0 50.4 52.9 16.3 99.0 325.5 23.0 7.5 12.9 11.6 31.5 12.5 34.0 6.3 32.1 38.1 5.4 42.5 96.5 25.2 5.5 7.8 1.6 6.2 9.0 6.2 2.2 11.9 19.5 3.9 4.9 5.1 19.5 6.7 6.9 13.8 12.9 15.4 4.1 18.0 2.9 5.6 4.1 4.8 7.9 13.5 14.6 7.2 6.9 13.5 12.8 13.3 28.2 12.6 4.9 7.7 7.2 60.6 3.8 3.8 10.7 6.1 3.0 10.8 12.3 7.5 2.2 20.7 5.4 4.9 5.1 2.9 7.6 9.7 12.4 2.7 4.6 5.8 4.7 17.2 16.7 14.1 9.5 21.5 35.7 2.6 23.4 4.0 13.6 0.0 0.5 0.0 4.4 2.0 18.5 1.7 5.5 6.4 1.1 2.1 4.8 3.5 0.2 1.0 5.5 1.4 8.0 1.8 23.5 27.0 52.9 49.7 24.9 17.2 18.1 20.9 15.9 12.9 34.0 25.2 16.4 3.2 2.0 17.3 5.7 64.5 47.5 20.5 67.2 71.4 9.4 15.1 5.7 8.6 11.9 1.8 4.2 2.6 4.9 26.0 7.9 16.1 2.3 25.4 30.6 18.6 8.3 3.6 7.1 11.8 1.2 26.5 31.1 64.2 2.5 2.7 6.8 31.8 2.5 42.1 6.2 7.2 8.2 3.4 19.4 1.5 21.8 7.7 19.6 8.4 1.2 39.0 5.2 5.0 1.2 26.0 14.7 38.7 10.5 35.4 58.8 7.9 5.0 29.7 6.6 9.6 19.4 2.0 11.1 95.5 81.1 2.3 11.9 13.7 6.0 28.7 OR13A1 ENSG00000256574 "Olfactory receptor family 13 subfamily A member 1" Q8NGR1 10 45302298-45315608 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "Daudi: 10.4;U-698: 9.3" "Not detected" "Not detected" HPA057237 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA057237: AB_2683378" "unprognostic (7.88e-2)" "unprognostic (1.90e-1)" "unprognostic (5.52e-2)" "unprognostic (2.33e-5)" "unprognostic (6.43e-3)" "unprognostic (6.04e-2)" "unprognostic (8.65e-2)" "unprognostic (3.59e-1)" "unprognostic (2.45e-1)" "unprognostic (2.54e-2)" "unprognostic (1.31e-1)" "unprognostic (1.67e-15)" "unprognostic (6.54e-2)" "unprognostic (2.87e-1)" "unprognostic (8.55e-2)" "unprognostic (4.09e-3)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.2 0.1 0.7 0.0 0.0 0.3 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 PABPN1 "OPMD, PAB2, PABP2" ENSG00000100836 "Poly(A) binding protein nuclear 1" Q86U42 14 23321289-23326185 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA000637 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nuclear speckles" "HPA000637: AB_1079553" "unprognostic (5.11e-3)" "unprognostic (2.65e-2)" "unprognostic (7.20e-2)" "unprognostic (2.95e-2)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.88e-2)" "unprognostic (1.47e-1)" "unprognostic (1.95e-3)" "prognostic favorable (9.66e-4)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.41e-7)" "unprognostic (1.52e-2)" "unprognostic (1.31e-2)" "unprognostic (1.07e-1)" "unprognostic (8.25e-3)" 133.2 178.7 187.0 86.4 183.9 136.9 127.7 193.4 249.3 165.6 184.5 184.1 107.6 176.0 130.3 151.0 175.6 63.4 138.1 185.8 196.6 187.7 194.8 130.0 103.9 186.0 182.2 176.3 138.8 101.0 199.0 79.7 181.6 179.4 101.5 126.6 130.4 85.8 131.5 136.9 167.8 97.4 175.6 174.3 159.3 230.1 186.3 147.6 189.8 94.1 116.5 146.3 144.0 190.4 127.2 133.9 298.3 216.6 125.5 143.1 191.4 120.4 121.6 168.4 157.4 168.0 223.0 229.7 67.0 157.0 180.6 186.4 337.7 169.7 230.7 195.2 116.7 173.5 208.1 435.5 145.2 273.5 220.2 157.1 164.7 125.0 149.1 240.9 188.1 196.0 164.5 174.6 159.8 239.6 296.1 334.5 328.6 151.2 149.3 289.1 114.8 136.2 196.1 256.2 205.6 159.9 161.4 143.2 129.6 196.9 114.2 196.3 153.2 112.1 153.8 110.4 161.8 207.3 153.0 276.5 51.4 221.4 138.7 15.7 7.6 8.5 6.0 5.8 4.9 7.4 6.1 5.5 6.1 9.3 7.5 7.0 10.0 10.1 7.2 13.8 7.6 2.5 187.0 183.9 193.4 249.3 185.8 196.6 186.0 182.2 181.6 175.6 186.3 190.4 66.3 35.3 49.4 0.0 83.3 157.8 84.4 74.0 158.2 120.1 110.2 89.5 14.3 77.2 51.2 126.9 146.0 70.0 102.5 85.5 13.7 52.6 55.6 71.8 80.8 75.0 161.4 94.2 0.0 57.2 67.4 72.4 68.8 78.6 24.1 169.3 66.0 121.6 63.2 77.4 0.0 107.2 54.9 84.7 119.0 45.9 81.1 85.5 53.4 0.0 104.4 55.8 65.9 0.0 0.0 59.2 91.6 59.8 102.2 88.7 88.9 40.3 49.8 80.2 72.3 57.5 85.0 41.8 33.3 187.4 179.9 62.8 67.3 107.6 108.1 114.6 PAX9 ENSG00000198807 "Paired box 9" P55771 14 36657568-36679362 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 81.0;lymphoid tissue: 20.5;parathyroid gland: 43.0;salivary gland: 51.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 45.3;Basal squamous epithelial cells: 174.8;Ionocytes: 40.7;Squamous epithelial cells: 172.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 12.3;HDLM-2: 58.3;PC-3: 18.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001572, CAB016239" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli Nucleoplasm "CAB016239: AB_2159984, HPA001572: " "unprognostic (3.09e-1)" "prognostic favorable (5.38e-4)" "unprognostic (1.56e-2)" "unprognostic (2.80e-2)" "unprognostic (1.40e-2)" "unprognostic (1.43e-2)" "unprognostic (5.93e-3)" "unprognostic (2.71e-3)" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (2.41e-2)" "unprognostic (9.44e-2)" "unprognostic (2.31e-4)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" 0.1 0.1 0.0 0.1 0.0 0.3 0.6 0.0 0.0 7.3 0.1 0.7 0.0 0.2 0.3 81.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.1 43.0 2.2 0.0 0.0 3.7 0.1 0.0 51.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 20.5 0.7 0.0 8.5 0.7 7.1 0.0 5.3 2.3 0.0 2.5 2.1 3.8 2.0 0.0 0.3 0.0 0.0 1.6 1.8 1.6 0.8 0.0 0.5 11.4 2.1 12.3 0.0 58.3 7.3 0.9 1.2 0.0 0.0 0.0 4.2 0.7 6.0 0.0 1.9 0.0 0.0 5.3 2.3 0.3 0.2 7.3 0.9 0.0 0.1 1.9 18.9 0.0 0.0 0.0 0.0 6.9 3.4 0.0 1.3 7.0 1.4 0.9 5.1 0.0 0.0 0.0 0.6 2.2 1.0 0.0 0.1 4.4 0.7 0.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 8.4 45.3 174.8 0.0 1.6 1.3 0.4 0.0 25.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.2 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 40.7 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 20.9 0.0 0.0 26.8 0.0 0.0 0.1 2.0 2.4 0.9 172.0 0.3 0.1 0.1 0.0 0.6 12.1 PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Predicted membrane proteins" "Apoptosis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 782.9;skin 1: 1115.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3312.8;Squamous epithelial cells: 3451.4;Suprabasal keratinocytes: 5828.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 555.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 39.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 39.8" "Cell line enhanced" "Detected in many" "hTCEpi: 1024.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA022269: AB_1855219" "prognostic unfavorable (5.46e-4)" "unprognostic (2.90e-1)" "unprognostic (1.94e-1)" "unprognostic (5.18e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.28e-3)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (4.02e-2)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" 27.1 9.3 7.0 9.9 7.1 1.5 131.0 7.8 8.6 201.6 13.7 40.9 50.2 23.2 47.9 782.9 61.2 37.9 53.9 6.8 8.1 21.9 93.7 27.0 3.3 9.2 7.8 6.4 33.1 40.6 13.1 38.7 8.6 60.7 38.4 8.7 295.9 46.8 5.7 1115.1 52.0 19.8 7.8 1.4 65.1 3.1 9.3 23.3 24.6 16.3 149.4 60.2 426.4 6.3 81.5 80.3 3.7 11.3 60.0 63.1 172.7 115.5 129.8 17.6 12.9 64.8 143.1 1.5 45.5 37.5 144.0 268.4 15.6 207.6 4.5 126.9 64.6 1.5 70.7 69.8 42.6 1.7 1.0 44.3 1024.8 2.2 111.8 91.7 71.3 5.8 2.4 31.3 3.0 53.4 1.5 4.6 34.4 174.6 47.1 1.5 28.6 0.9 108.2 94.0 29.3 3.7 141.2 68.7 59.6 90.7 36.4 18.4 82.6 29.4 12.1 31.7 2.1 11.1 17.4 1.3 23.0 1.5 65.5 39.8 0.0 0.0 4.3 0.0 7.6 2.0 5.3 3.8 0.0 1.0 0.6 2.3 0.3 0.1 0.0 0.0 8.9 1.3 7.0 7.1 7.8 8.6 6.8 8.1 9.2 7.8 8.6 7.8 9.3 6.3 13.9 211.5 84.2 0.7 8.1 3312.8 1415.8 1383.2 1110.4 3.3 371.4 305.0 137.7 260.2 728.5 154.5 16.7 994.5 17.6 374.8 62.6 588.0 2.1 1013.4 78.1 71.8 147.2 13.9 1.2 305.1 990.1 83.8 197.2 777.1 10.8 0.5 21.4 171.3 82.0 3.3 2.1 185.0 736.5 3.8 259.2 2.7 10.5 12.8 350.4 12.2 10.3 29.1 3.1 2.0 0.5 655.0 316.7 2.6 43.2 789.2 355.0 10.6 743.5 28.3 6.6 15.4 82.6 2.4 1.4 3451.4 5828.3 824.0 67.2 73.5 218.6 1546.6 PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "monocytes: 214.9;Squamous epithelial cells: 496.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Cell line enhanced" "Detected in all" "A549: 1445.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" 115.8 51.0 49.5 59.8 49.2 400.2 89.0 52.9 49.3 75.9 52.5 52.9 91.6 23.1 41.9 572.4 30.0 94.2 34.3 47.4 54.3 53.2 81.3 88.5 38.1 57.0 54.6 35.7 32.0 52.7 43.8 47.4 55.4 30.4 46.3 49.1 133.7 22.9 34.7 50.0 70.7 35.0 49.7 110.4 61.4 68.3 59.2 53.6 71.8 28.2 73.8 61.8 126.9 52.0 191.5 1445.2 319.3 340.6 445.4 274.0 71.8 124.8 185.9 144.4 195.3 219.2 190.4 163.5 151.0 109.2 202.4 148.0 225.6 192.1 96.4 127.5 199.9 227.8 264.3 452.1 136.3 390.9 249.7 196.5 92.2 229.4 55.5 186.9 344.0 223.0 305.3 145.7 183.5 202.5 321.4 179.4 194.7 221.0 109.1 252.7 298.1 312.2 199.6 105.5 178.0 154.1 99.1 153.5 137.5 196.7 173.3 308.5 369.3 81.1 149.6 98.3 134.5 111.6 256.0 323.5 175.1 393.9 73.6 1060.2 321.0 1074.7 23.2 137.7 26.5 33.1 21.4 20.8 144.6 23.3 21.1 22.3 332.6 19.7 105.6 98.7 23.1 225.0 49.5 49.2 52.9 49.3 47.4 54.3 57.0 54.6 55.4 49.7 59.2 52.0 7.4 19.2 35.0 11.8 24.9 13.0 30.8 78.0 70.6 7.8 30.4 18.5 11.0 50.1 73.2 20.2 18.8 134.6 29.8 24.3 52.8 52.1 10.9 17.8 18.6 22.6 23.4 55.7 8.6 40.3 40.7 37.5 41.8 24.5 25.9 53.9 16.1 66.2 134.6 1.7 12.6 30.2 59.0 163.8 30.9 13.4 17.1 150.9 17.8 4.7 214.9 16.5 10.3 13.6 9.0 38.7 26.7 10.5 41.9 43.5 66.6 55.1 46.2 20.2 19.7 23.4 21.5 41.5 38.4 496.0 16.6 81.3 19.4 27.3 51.7 76.1 PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 38.9;skin 1: 73.7;vagina: 21.4" "Cell type enriched" "Detected in single" 12 "Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;head and neck cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "HaCaT: 3.8;HDLM-2: 1.6;hTCEpi: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 73.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 7.6 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 PHF13 MGC43399 ENSG00000116273 "PHD finger protein 13" Q86YI8 1 6613731-6624030 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026830 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA026830: AB_1855288" "unprognostic (6.59e-3)" "unprognostic (7.71e-2)" "unprognostic (2.62e-2)" "unprognostic (9.17e-2)" "unprognostic (1.65e-1)" "unprognostic (8.41e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (9.84e-3)" "unprognostic (2.62e-1)" "unprognostic (1.59e-1)" "unprognostic (8.73e-3)" "unprognostic (1.40e-2)" "unprognostic (1.68e-3)" "unprognostic (1.58e-1)" "unprognostic (3.86e-2)" "unprognostic (6.68e-2)" "unprognostic (1.05e-1)" 11.5 8.9 7.9 4.7 7.6 9.5 11.4 7.0 8.5 18.5 7.2 16.5 5.2 17.1 10.1 15.1 15.2 10.5 8.3 8.0 8.6 7.7 12.3 10.0 6.2 8.4 8.0 14.1 10.0 9.8 9.9 7.9 7.4 11.4 3.4 6.2 9.6 10.5 10.0 14.4 7.7 8.0 7.4 7.0 9.6 34.0 9.4 8.7 8.8 6.9 5.8 12.3 14.4 8.8 19.2 8.9 25.8 31.8 13.0 17.7 15.1 29.0 21.2 22.5 20.4 17.7 18.2 17.2 11.1 22.2 13.9 15.9 17.1 18.6 22.1 22.9 22.3 26.3 14.3 15.1 13.6 7.0 16.9 19.8 7.9 21.6 10.1 24.9 14.0 16.0 31.7 12.1 19.4 21.3 16.4 19.8 19.1 10.1 15.3 27.7 20.3 9.3 12.2 9.8 18.3 22.7 12.4 21.5 19.1 17.7 17.2 13.4 14.9 39.1 19.1 16.3 14.3 25.2 26.1 29.0 21.6 18.0 8.5 2.3 1.3 4.6 2.4 1.2 3.6 1.5 3.0 2.3 1.3 1.4 2.0 2.4 4.1 2.8 2.0 1.2 2.5 2.3 7.9 7.6 7.0 8.5 8.0 8.6 8.4 8.0 7.4 7.4 9.4 8.8 11.8 3.2 5.0 8.5 8.9 37.5 18.0 7.8 62.0 7.2 23.9 14.7 5.6 5.7 4.5 3.7 0.0 11.4 8.1 4.3 9.8 6.2 7.9 11.5 17.6 10.2 7.8 12.0 3.0 3.7 12.2 15.1 4.6 14.3 5.1 9.6 8.2 9.5 4.3 18.5 3.9 4.2 2.0 4.1 19.1 7.4 10.5 5.0 16.0 1.9 4.5 10.6 1.0 3.0 5.0 5.8 2.2 7.9 8.0 17.5 3.6 4.6 5.4 6.0 26.3 12.1 15.1 14.7 33.2 41.1 40.2 21.2 9.5 8.4 2.8 12.0 PITX1 "BFT, POTX, PTX1" ENSG00000069011 "Paired like homeodomain 1" P78337 5 135027734-135034813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 711.6;vagina: 199.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 121.0;Basal squamous epithelial cells: 409.2;Squamous epithelial cells: 1069.0;Urothelial cells: 257.3" "Cancer enhanced" "Detected in many" "cervical cancer: 73.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 141.4;HeLa: 108.9;K-562: 112.1;T-47d: 157.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA008743 Approved Approved Nucleoli Yes No "Cluster 84: Esophagus - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli "HPA008743: AB_1855413" "unprognostic (1.84e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (4.62e-2)" "unprognostic (5.08e-2)" "unprognostic (5.26e-3)" "unprognostic (1.03e-2)" "unprognostic (1.66e-2)" "unprognostic (5.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.27e-1)" "unprognostic (5.80e-14)" "unprognostic (6.22e-2)" "unprognostic (1.33e-1)" "unprognostic (5.98e-3)" "unprognostic (4.97e-3)" 1.5 1.9 0.7 7.7 0.6 0.3 0.6 0.9 0.7 83.5 4.7 11.4 12.1 0.8 0.0 711.6 0.5 1.1 0.2 0.9 1.1 0.1 0.3 0.4 0.1 0.8 0.9 0.6 0.4 0.0 164.7 2.7 0.7 20.1 2.0 0.1 137.5 0.0 14.1 2.0 7.9 0.4 0.5 0.2 41.9 2.2 0.7 0.0 0.2 20.1 12.6 85.0 199.0 0.8 57.5 36.9 0.0 44.7 1.4 0.9 13.4 9.6 14.6 5.1 2.3 141.4 32.5 59.9 17.6 0.9 12.6 17.6 6.4 25.5 0.3 0.7 48.2 13.4 108.9 38.4 15.6 5.8 0.1 1.4 18.4 0.0 4.9 0.3 0.1 10.1 112.1 0.2 1.9 18.4 0.6 12.3 0.1 4.8 31.8 18.5 1.1 1.2 0.6 17.9 20.2 0.1 48.4 24.1 0.0 0.5 157.5 4.2 1.5 6.1 13.4 3.5 17.0 0.1 0.2 40.7 8.1 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.7 0.9 1.1 0.8 0.9 0.7 0.5 0.7 0.8 0.1 0.0 0.0 0.0 0.2 1.3 121.0 12.8 409.2 1.0 2.5 2.7 2.3 1.5 8.6 0.0 0.0 0.8 0.0 4.2 0.0 0.2 4.2 0.3 0.6 1.2 0.0 50.8 0.0 0.4 2.1 28.8 0.5 0.2 0.0 2.7 0.0 0.0 0.9 0.0 0.0 2.4 6.1 0.0 0.3 5.7 0.3 1.0 0.0 0.0 0.0 0.4 1.0 0.0 0.1 16.9 3.4 0.0 3.1 101.6 0.3 0.2 6.1 1.8 0.0 2.1 4.5 2.2 5.6 1069.0 6.8 7.7 0.9 0.7 2.5 257.3 PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 416.7;skin 1: 699.9;vagina: 200.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 139.7;Squamous epithelial cells: 234.5;Suprabasal keratinocytes: 409.0" "Group enriched" "Detected in many" 4 "cervical cancer: 125.5;head and neck cancer: 295.4;lung cancer: 79.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 234.6;HBEC3-KT: 144.2;hTCEpi: 501.4;hTERT-HME1: 132.5;PC-3: 192.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2500000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "CAB033130: AB_2164139, HPA027221: AB_10599737" "unprognostic (3.55e-3)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.49e-1)" "unprognostic (5.02e-2)" "unprognostic (2.20e-3)" "unprognostic (2.67e-1)" "unprognostic (9.17e-3)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-3)" 9.7 0.2 0.3 0.2 0.2 0.2 31.7 0.0 1.1 102.9 0.0 0.4 0.2 0.2 3.3 416.7 1.0 0.1 0.6 0.2 0.0 0.4 0.3 5.0 0.2 0.0 1.1 0.2 0.5 0.0 0.6 5.5 0.5 32.3 0.2 32.4 60.5 9.1 6.6 699.9 0.6 0.0 0.0 0.1 0.4 0.2 0.0 23.7 0.5 2.9 48.0 3.2 200.4 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 1.1 0.0 0.2 0.1 0.0 234.6 0.0 144.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 501.4 5.6 132.5 0.0 0.0 0.1 0.0 0.2 0.0 38.4 0.0 0.1 0.0 0.0 192.6 0.0 0.4 0.0 0.0 1.1 0.0 0.0 18.3 4.4 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 1.1 0.2 0.0 0.0 1.1 0.5 0.0 0.0 0.0 39.9 0.0 0.0 0.3 0.0 139.7 58.2 57.1 63.7 34.7 7.7 17.9 1.9 0.0 20.0 0.0 2.1 0.1 0.1 0.1 0.0 2.5 0.1 0.2 0.1 4.1 0.0 0.0 0.6 1.1 0.1 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.0 0.1 1.6 4.1 0.0 16.5 0.8 0.0 0.4 16.0 0.0 0.0 5.2 0.0 0.0 0.1 16.1 0.1 0.0 0.0 25.7 0.2 0.1 2.8 37.4 0.0 6.1 2.0 0.0 0.1 234.5 409.0 0.1 1.1 0.0 0.1 47.5 PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 728.1;vagina: 288.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Squamous epithelial cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.5;HaCaT: 191.1;MCF7: 71.5;SiHa: 102.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042550, HPA059859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 80000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA042550: AB_2678048, HPA059859: AB_2684145" "unprognostic (2.12e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-2)" "unprognostic (2.84e-2)" "unprognostic (1.40e-1)" "unprognostic (3.70e-3)" "unprognostic (5.58e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.41e-2)" "unprognostic (1.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" 56.3 4.9 2.5 1.0 3.2 0.2 39.8 0.3 4.2 163.0 3.3 10.4 6.5 5.7 7.3 728.1 11.5 7.1 5.7 3.6 0.0 13.2 13.3 18.6 0.4 0.0 2.8 5.9 10.6 4.1 14.3 6.4 1.1 17.3 3.4 2.4 149.5 11.5 12.0 188.4 12.3 1.7 0.0 0.3 11.1 1.9 0.0 3.5 22.1 5.3 57.0 22.0 288.6 0.5 24.0 8.6 0.1 0.1 60.0 86.5 29.6 0.1 1.6 0.2 0.6 39.5 59.5 0.4 13.5 1.2 3.4 191.1 1.3 23.0 0.0 0.0 1.3 0.1 46.3 7.1 3.8 0.1 0.1 4.2 20.7 0.2 7.1 4.6 0.1 0.2 0.2 0.2 0.1 71.5 0.1 0.2 6.0 31.3 18.1 0.1 0.1 30.0 44.6 37.5 30.9 0.3 102.5 33.8 0.3 8.9 17.4 0.5 0.3 0.2 0.3 0.3 0.1 0.4 1.1 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.2 0.3 4.2 3.6 0.0 0.0 2.8 1.1 0.0 0.0 0.5 4.1 73.7 29.1 1.6 1.2 35.1 32.5 30.5 35.9 8.4 18.8 13.8 5.1 35.8 42.6 57.0 6.2 2.1 2.0 3.6 1.9 18.4 0.7 31.6 4.1 8.0 39.4 0.0 6.6 4.5 1.6 38.0 9.2 28.0 0.0 0.8 2.9 12.7 0.7 1.7 2.5 3.8 18.3 0.9 9.0 1.3 55.3 1.4 17.8 1.0 1.2 3.7 2.1 1.0 1.7 23.4 8.3 4.1 0.2 35.1 13.5 1.2 32.5 12.5 0.0 28.7 4.3 3.9 3.1 138.0 51.3 1.4 2.7 0.4 4.8 53.2 PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.5;esophagus: 388.6;vagina: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Horizontal cells: 11.8;Squamous epithelial cells: 9.6;Urothelial cells: 11.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.1;SK-BR-3: 24.4;T-47d: 14.6;U-266/70: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" NA NA 8700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" 1.0 0.4 0.9 0.2 0.9 0.3 1.3 1.0 2.0 83.5 0.6 1.0 0.0 1.0 0.0 388.6 0.7 0.2 0.4 0.8 1.4 1.1 0.6 0.6 0.3 1.2 1.5 0.5 0.8 0.7 1.5 0.1 1.0 1.0 0.0 0.2 52.5 0.4 0.3 3.3 0.6 0.0 1.0 0.6 0.8 2.6 1.2 0.6 0.8 0.0 29.9 0.8 134.2 0.9 0.1 0.3 0.4 2.1 0.3 0.7 6.1 0.0 0.2 0.2 0.2 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.5 0.1 0.1 0.0 1.0 0.0 0.3 1.2 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.6 0.0 2.0 0.0 1.1 1.4 0.2 0.0 1.0 0.2 0.1 0.2 0.3 0.7 2.8 0.0 24.4 0.6 0.1 14.6 1.8 0.0 0.4 0.0 0.1 0.0 5.2 3.7 0.5 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.9 1.0 2.0 0.8 1.4 1.2 1.5 1.0 1.0 1.2 0.9 1.5 9.6 5.8 0.0 0.5 1.8 2.5 1.3 0.6 5.2 5.1 6.2 1.2 1.5 5.6 1.8 4.2 0.7 0.5 1.2 0.0 1.5 3.3 0.6 1.4 1.8 0.0 0.0 0.4 1.4 0.6 1.4 1.1 1.6 3.8 1.1 0.4 0.7 0.3 11.8 0.8 0.5 0.0 0.3 3.1 1.0 0.3 0.8 1.8 1.9 0.9 2.6 0.0 0.0 0.3 1.1 1.2 0.0 0.2 1.7 0.1 0.7 3.4 6.6 0.0 2.7 1.5 3.0 3.9 9.6 2.4 3.3 1.3 0.6 1.4 11.1 RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Paneth cells: 249.6;Squamous epithelial cells: 300.6;Undifferentiated cells: 244.6;Urothelial cells: 232.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "BEWO: 120.9;CAPAN-2: 119.9;MCF7: 171.5;OE19: 392.3;RT4: 153.4;SK-BR-3: 243.3;T-47d: 227.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010872, CAB033645" Enhanced Uncertain "Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions, Cytosol" "CAB033645: AB_1128883, HPA010872: AB_1079729" "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" 0.6 0.1 0.1 10.2 0.1 0.1 52.0 0.3 0.3 76.2 0.0 86.2 72.9 7.3 37.5 423.3 47.5 26.4 0.1 0.0 0.0 41.6 1.7 39.2 0.4 0.1 0.1 0.4 57.1 68.9 27.5 12.4 0.1 36.3 78.1 0.0 105.3 28.4 0.9 210.0 65.6 3.7 0.2 0.2 80.9 0.3 0.1 10.1 50.6 0.0 44.0 69.9 148.2 0.3 93.3 0.0 0.0 0.0 0.0 0.0 120.9 0.0 0.0 0.0 0.0 90.4 119.9 0.0 0.1 0.0 0.0 109.5 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 105.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 171.5 0.0 0.4 4.8 392.3 0.0 0.1 0.0 0.3 0.0 153.4 13.3 0.0 0.0 243.3 0.3 21.1 227.9 0.4 0.0 0.2 0.2 0.0 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 1.2 28.9 41.0 0.0 1.5 55.1 102.9 113.9 74.0 0.0 121.4 137.7 0.1 94.4 98.7 86.5 0.0 102.1 2.3 197.8 166.3 170.4 0.0 58.6 6.4 2.6 85.4 0.0 0.1 150.3 30.0 2.3 96.4 66.2 5.7 0.0 0.0 0.4 7.3 0.0 0.1 208.5 89.5 0.0 5.8 0.0 0.3 2.1 21.4 0.0 3.6 0.0 0.0 0.0 0.1 197.3 249.6 0.0 0.3 114.0 195.9 35.5 66.3 0.0 0.0 0.0 6.8 0.2 1.1 300.6 154.7 80.3 2.7 0.0 244.6 232.3 RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883375-149898102 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 21.9;esophagus: 62.8;skin 1: 21.6;vagina: 27.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 12.4;Early spermatids: 10.0;Late spermatids: 5.6;Respiratory ciliated cells: 14.6;Squamous epithelial cells: 17.2;Suprabasal keratinocytes: 6.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 19.6;HeLa: 24.4;hTCEpi: 19.1;SiHa: 9.9;U-87 MG: 7.7" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" 3.7 0.8 0.6 0.1 0.4 0.1 1.9 1.0 0.7 21.9 0.8 0.2 0.1 0.3 0.0 62.8 0.8 0.1 0.5 0.5 0.5 2.2 0.1 0.3 0.1 0.4 0.3 0.1 0.1 0.0 0.2 0.5 0.5 0.3 0.3 0.1 12.9 0.3 1.6 21.6 0.1 0.5 0.1 0.9 0.3 0.4 0.4 0.1 0.3 0.2 11.6 1.9 27.5 0.5 1.8 1.0 0.0 0.0 0.2 1.3 0.0 0.1 0.9 0.1 0.3 0.0 4.3 0.0 2.6 4.4 1.4 1.7 0.0 19.6 0.2 0.3 0.0 0.1 24.4 0.0 0.0 0.0 0.0 0.4 19.1 1.0 3.9 0.4 0.1 0.1 0.0 1.3 0.8 0.0 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.3 0.4 0.9 0.2 0.0 9.9 1.5 0.0 0.0 1.2 0.0 1.8 0.8 0.3 0.2 0.9 0.0 0.0 0.0 7.7 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 1.0 0.7 0.5 0.5 0.4 0.3 0.5 0.1 0.4 0.5 1.0 0.0 0.0 0.3 0.0 2.2 1.1 12.4 1.8 0.6 0.3 0.6 0.3 1.5 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 2.5 0.1 1.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.1 0.0 0.0 0.3 5.6 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.5 1.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 14.6 0.4 0.0 0.3 0.4 0.0 0.2 17.2 6.5 0.0 0.2 0.1 0.2 1.6 RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.7;Excitatory neurons: 47.8;Proximal enterocytes: 55.3;Squamous epithelial cells: 95.4;Suprabasal keratinocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HaCaT: 92.4;hTCEpi: 45.8;T-47d: 80.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" 6.3 4.4 38.4 6.8 36.1 4.4 9.1 12.1 58.3 48.7 1.8 53.8 48.3 4.6 9.9 199.1 6.6 8.8 6.8 55.1 12.9 3.8 10.5 8.0 2.2 12.0 11.4 3.7 7.9 1.1 14.2 2.3 10.9 17.7 44.5 6.1 27.4 6.9 12.6 237.7 40.6 4.0 8.3 7.3 31.8 10.2 15.2 3.3 4.5 2.8 20.7 21.9 113.2 30.6 5.3 2.6 13.7 10.2 1.5 3.3 6.6 1.9 1.4 2.7 3.2 6.0 7.6 4.2 1.9 2.7 2.4 92.4 2.7 3.3 3.8 7.7 6.9 2.5 3.6 6.0 1.7 5.2 8.5 3.9 45.8 2.8 1.3 4.0 4.1 13.9 1.9 2.8 2.1 14.6 4.9 6.3 4.3 26.1 2.6 8.8 1.6 2.6 1.7 27.6 26.2 5.3 3.3 31.2 1.3 11.5 80.7 3.9 7.9 3.3 6.8 3.5 3.2 4.6 4.7 3.4 7.8 3.2 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 38.4 36.1 12.1 58.3 55.1 12.9 12.0 11.4 10.9 8.3 15.2 30.6 1.9 0.0 1.1 7.5 1.0 45.5 9.7 14.0 13.1 5.7 2.6 3.7 2.4 11.5 10.9 1.8 6.2 0.2 0.7 87.7 0.0 0.9 2.7 5.9 2.1 2.2 4.9 2.7 47.8 0.8 0.3 1.4 32.6 9.4 5.7 1.7 3.9 4.4 0.5 1.7 32.1 31.9 6.1 1.2 5.2 2.2 3.4 1.9 5.4 1.0 2.4 2.9 1.0 8.0 5.0 1.6 44.6 3.8 0.1 10.9 55.3 0.1 6.5 4.4 0.0 2.1 1.9 12.0 15.0 95.4 97.0 0.7 1.1 1.8 44.1 39.2 RARG "NR1B3, RARC" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.6;skin 1: 121.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 42.7;Squamous epithelial cells: 69.9;Suprabasal keratinocytes: 55.8;Urothelial cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.8" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 101.0;MCF7: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA053883: AB_2682292" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (6.11e-2)" "prognostic unfavorable (3.68e-6)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (1.08e-2)" "unprognostic (3.54e-3)" "unprognostic (7.21e-3)" "unprognostic (3.78e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (5.41e-3)" "unprognostic (1.98e-2)" "unprognostic (5.94e-3)" "unprognostic (7.41e-2)" 17.4 16.2 10.2 5.7 9.7 3.7 19.4 13.0 10.9 55.0 10.8 22.7 2.5 23.3 6.0 141.6 27.2 15.7 17.3 9.7 9.5 12.5 3.2 15.2 5.9 10.3 10.0 20.5 8.5 7.2 8.7 9.5 9.3 26.9 7.8 3.9 30.6 16.2 6.9 121.4 10.4 13.0 10.0 10.2 14.5 4.8 9.5 5.1 22.6 10.6 22.5 26.2 69.3 10.0 22.8 24.7 5.5 50.9 55.0 46.8 1.7 23.2 50.0 29.7 23.3 8.3 101.0 0.5 12.5 93.6 16.2 74.3 18.4 44.6 7.4 5.7 9.4 3.3 18.6 7.4 23.2 0.0 9.1 34.8 63.9 28.5 6.4 74.7 12.7 4.6 0.8 9.8 11.9 110.3 1.3 1.1 16.3 30.4 42.7 7.3 1.9 18.1 8.9 37.1 4.4 22.9 47.0 50.6 32.1 6.8 43.9 1.4 13.8 35.4 16.5 23.6 1.5 4.2 2.6 1.8 43.4 3.8 51.3 1.8 3.1 0.9 7.4 0.9 18.8 2.0 6.5 5.4 6.7 0.6 5.2 4.7 0.0 2.3 0.0 0.6 1.8 4.0 10.2 9.7 13.0 10.9 9.7 9.5 10.3 10.0 9.3 10.0 9.5 10.0 10.7 3.2 7.0 21.2 2.5 34.2 24.1 21.6 42.7 0.5 18.0 15.6 3.7 11.5 11.1 3.7 2.1 7.5 6.2 3.2 0.0 10.5 0.1 3.6 14.4 11.0 1.8 0.8 2.5 5.1 1.2 19.6 13.7 3.4 1.3 0.3 20.3 0.1 2.7 0.0 3.0 2.1 12.2 4.1 13.3 0.5 5.3 4.9 8.8 6.5 1.8 3.6 5.2 7.1 0.7 14.3 4.4 5.3 3.0 19.2 0.2 0.5 3.9 5.2 6.6 9.5 22.0 0.8 5.6 69.9 55.8 1.8 7.2 0.4 5.5 45.7 RASSF10 ENSG00000189431 "Ras association domain family member 10" A6NK89 11 13009316-13012119 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.0;skin 1: 6.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Distal tubular cells: 25.4;Gastric mucus-secreting cells: 17.9;Squamous epithelial cells: 60.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 8.9;CAPAN-2: 7.8;HaCaT: 12.6;HMC-1: 6.2;RPTEC TERT1: 11.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040406 Approved Vesicles,Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles Cytosol "HPA040406: AB_2732485" "unprognostic (6.71e-2)" "unprognostic (5.12e-2)" "unprognostic (5.06e-2)" "unprognostic (2.41e-3)" "unprognostic (6.25e-3)" "prognostic favorable (2.76e-4)" "unprognostic (3.43e-3)" "unprognostic (8.04e-2)" "unprognostic (5.89e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (4.12e-5)" "unprognostic (4.45e-2)" "unprognostic (1.73e-1)" "unprognostic (2.88e-1)" "unprognostic (1.65e-2)" 0.3 0.0 0.4 0.0 0.8 0.0 1.3 0.2 0.5 0.6 0.3 0.4 1.2 0.1 0.1 6.0 3.0 0.3 0.3 0.2 0.3 3.4 0.0 1.2 0.0 0.7 1.0 0.0 0.0 2.1 0.1 0.0 0.7 0.6 0.4 0.0 4.6 0.2 0.7 6.6 0.5 0.0 1.0 0.0 3.6 0.5 0.1 0.5 0.1 0.2 0.5 1.1 1.5 0.5 0.4 8.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.8 0.0 0.5 0.0 0.3 12.6 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 2.2 0.0 1.3 0.0 0.0 11.9 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.2 0.5 0.2 0.3 0.7 1.0 0.7 1.0 0.1 0.5 2.0 0.0 5.1 0.7 0.1 0.0 6.3 0.0 64.3 0.0 5.8 8.0 0.9 0.0 2.5 1.8 0.0 0.2 0.0 0.9 25.4 0.6 0.0 6.0 1.1 1.4 2.4 0.0 0.0 0.2 0.0 0.2 17.9 11.1 1.3 0.0 3.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.3 0.5 0.0 1.9 0.0 0.9 0.0 0.0 0.0 11.5 1.2 0.0 0.0 1.9 0.0 4.5 7.3 0.0 0.0 0.5 0.3 0.0 0.8 60.0 0.0 0.0 0.2 0.0 5.5 3.5 RGS14 ENSG00000169220 "Regulator of G protein signaling 14" O43566 5 177357924-177372596 "Predicted intracellular proteins" "Cell cycle, Cell division" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 72.8;Proximal tubular cells: 113.7;Squamous epithelial cells: 95.8;Suprabasal keratinocytes: 115.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 110.4;cerebral cortex: 67.9;hippocampal formation: 56.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 112.5;HMC-1: 95.4;NB-4: 44.8;RPMI-8226: 57.9" "Group enriched" "Detected in many" 10 "amygdala: 66.0;basal ganglia: 57.9;cerebral cortex: 46.8;hippocampal formation: 93.6;white matter: 23.8" "Region enhanced" "Detected in many" "basal ganglia: 102.1" "HPA046847, HPA061819" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Intermediate filaments" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Vesicles, Plasma membrane, Intermediate filaments" "HPA046847: AB_2679836, HPA061819: " "unprognostic (6.05e-3)" "unprognostic (1.65e-2)" "unprognostic (8.57e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.97e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.95e-2)" "unprognostic (4.34e-2)" "unprognostic (2.04e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-2)" "unprognostic (2.78e-2)" 3.5 2.8 16.0 13.9 110.4 22.4 2.9 0.0 67.9 3.1 1.8 3.7 6.3 2.3 0.4 10.0 7.7 4.3 1.3 56.4 4.5 8.5 28.7 5.5 18.1 0.0 0.4 1.1 3.7 1.5 2.4 1.4 0.1 3.5 0.9 0.0 6.2 2.1 2.6 6.1 11.0 1.8 0.1 27.7 4.9 1.9 15.2 16.3 6.1 0.9 6.6 4.1 5.0 3.2 5.4 1.1 2.3 1.4 0.1 0.0 3.7 0.2 0.0 0.5 0.6 3.7 10.4 13.3 7.3 0.4 1.3 10.6 0.2 3.8 0.0 112.5 0.5 20.7 1.0 4.7 0.9 16.3 95.4 1.8 1.1 0.6 0.7 1.4 0.6 14.9 3.5 26.5 0.2 0.4 21.7 44.8 1.7 5.4 2.8 10.2 0.3 57.9 1.5 1.6 0.4 1.9 0.4 0.4 8.8 0.0 3.5 25.2 1.1 0.2 1.9 0.0 9.7 13.9 7.1 5.8 1.6 30.3 2.4 70.6 39.9 148.8 62.4 37.9 63.0 27.7 57.9 57.8 39.8 26.6 47.4 43.1 140.0 23.6 41.2 17.6 60.9 43.9 16.0 110.4 0.0 67.9 56.4 4.5 0.0 0.4 0.1 0.1 15.2 3.2 5.3 6.4 4.4 2.6 27.3 68.8 23.9 15.4 72.8 0.7 8.9 11.8 2.3 37.1 5.6 11.0 2.1 3.9 41.4 4.2 31.3 11.4 0.6 19.5 2.0 6.5 4.8 7.4 4.6 16.7 10.4 5.4 12.2 8.1 24.7 2.8 8.2 64.0 26.1 0.0 1.5 10.0 10.2 17.0 23.3 1.5 2.8 18.2 21.4 6.5 18.1 9.9 48.4 0.5 0.3 12.8 17.2 2.2 18.0 14.1 16.8 113.7 11.7 2.0 0.0 1.6 4.6 0.1 20.3 95.8 115.1 3.3 51.2 1.1 4.4 20.0 RHCG "C15orf6, PDRC2, RHGK, SLC42A3" ENSG00000140519 "Rh family C glycoprotein" Q9UBD6 15 89471398-89496589 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 4022.4;vagina: 1728.8" "Cell type enriched" "Detected in many" 21 "Squamous epithelial cells: 1544.7" "Cancer enhanced" "Detected in many" "cervical cancer: 152.9;head and neck cancer: 154.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.8;hTCEpi: 2.0;RT4: 1.2" "Region enriched" "Detected in many" 5 "olfactory bulb: 8.4" "Low region specificity" "Detected in some" "HPA041874, HPA043317" Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA041874: AB_2677719, HPA043317: AB_2678424" "unprognostic (1.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-3)" "unprognostic (1.98e-2)" "unprognostic (9.39e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (9.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (2.55e-3)" "unprognostic (2.68e-1)" "unprognostic (2.80e-2)" "unprognostic (2.27e-1)" "unprognostic (9.45e-3)" 1.3 2.1 5.3 0.0 5.4 0.0 0.8 4.9 6.9 823.5 3.9 0.5 0.0 0.6 0.0 4022.4 0.7 0.7 1.4 5.1 4.9 117.4 3.4 0.3 0.0 4.8 4.9 0.8 3.2 0.0 4.3 0.0 4.8 3.4 0.0 2.5 593.6 0.8 1.0 14.6 0.9 0.3 5.1 0.6 3.5 1.3 5.0 0.8 0.5 0.0 461.7 3.7 1728.8 5.2 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.3 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.4 4.9 6.9 5.1 4.9 4.8 4.9 4.8 5.1 5.0 5.2 0.0 0.0 0.0 2.0 0.3 1.3 28.9 22.9 6.2 1.0 0.9 0.5 0.7 0.0 47.6 14.7 0.0 0.0 0.0 0.6 15.6 1.5 2.0 0.0 0.1 0.7 0.0 0.0 6.0 0.4 0.0 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 2.0 0.0 0.7 1.4 0.0 1.5 0.0 0.0 0.0 64.4 0.0 4.0 0.3 0.7 4.8 0.0 0.0 34.8 0.0 0.0 1.6 2.8 0.0 0.0 5.4 1.5 0.1 1544.7 17.8 0.0 0.3 0.0 0.2 70.5 RHOV "ARHV, Chp, WRCH2" ENSG00000104140 "Ras homolog family member V" Q96L33 15 40872214-40874234 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 211.8;skin 1: 129.8;vagina: 92.2" "Cell type enhanced" "Detected in many" "Paneth cells: 142.3;Squamous epithelial cells: 375.0;Suprabasal keratinocytes: 283.0;Urothelial cells: 275.1" "Cancer enhanced" "Detected in many" "cervical cancer: 91.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SK-BR-3: 328.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053343 Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA053343: AB_2682122" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (8.29e-3)" "unprognostic (4.34e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.19e-4)" "unprognostic (3.29e-3)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (8.43e-3)" "unprognostic (5.63e-3)" 0.5 0.1 0.9 0.2 0.9 0.2 16.0 1.1 1.8 26.3 0.5 2.8 0.6 0.7 9.5 211.8 2.7 0.5 0.1 1.0 1.1 5.5 0.2 2.3 0.2 2.1 0.8 0.3 16.3 2.2 3.0 3.2 2.4 16.6 2.6 0.0 44.3 2.4 0.2 129.8 0.6 0.1 0.8 0.1 1.2 0.3 1.9 2.6 0.5 0.0 23.3 20.7 92.2 0.9 1.6 9.7 0.1 2.7 0.2 0.0 5.2 0.1 0.8 0.4 0.2 4.0 4.4 0.0 2.4 0.0 0.3 77.9 4.5 0.6 0.2 10.5 12.5 0.5 11.3 0.6 0.0 0.5 0.0 0.3 6.0 0.3 0.1 0.4 0.1 2.3 2.1 0.5 0.0 27.2 0.6 2.3 1.7 19.3 3.7 4.0 0.4 1.8 5.1 34.3 4.0 0.8 8.0 328.9 0.2 0.5 40.9 0.3 0.1 0.0 1.1 0.2 0.3 0.0 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.1 1.8 1.0 1.1 2.1 0.8 2.4 0.8 1.9 0.9 0.6 0.0 3.2 0.3 0.5 84.1 42.5 80.9 19.9 0.0 75.2 48.5 0.9 2.8 103.0 29.5 0.0 60.7 1.9 43.1 13.7 107.5 0.0 18.5 1.9 2.5 22.7 0.0 1.5 56.2 6.0 2.0 7.1 25.5 1.3 0.4 0.0 0.0 4.6 0.0 0.5 54.7 67.1 0.0 13.3 0.0 0.0 0.8 32.0 0.0 3.6 0.0 0.0 0.0 0.3 13.8 142.3 0.7 0.1 89.8 1.0 0.9 26.2 0.0 0.0 0.2 7.3 0.0 0.9 375.0 283.0 42.4 1.9 0.0 66.3 275.1 S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2340.8;Paneth cells: 1098.9;Proximal enterocytes: 1549.1;Squamous epithelial cells: 3205.8;Suprabasal keratinocytes: 3612.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 798.6;HaCaT: 1072.9;HBEC3-KT: 1527.6;hTCEpi: 2232.0;OE19: 1675.1;SK-BR-3: 1579.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" 2.2 0.8 1.5 24.9 1.6 0.2 78.3 1.5 2.0 530.8 1.3 241.0 265.4 5.4 14.7 3719.5 20.4 18.5 4.2 1.5 1.5 70.1 16.3 82.7 0.6 1.5 1.5 1.4 17.7 125.2 5.1 1.1 1.5 19.6 240.0 0.0 550.3 39.0 2.2 608.0 209.0 13.1 1.4 1.3 119.2 0.7 1.7 149.0 98.6 0.0 449.7 32.9 1174.2 1.5 798.6 0.2 0.1 0.2 0.2 0.3 7.4 0.2 0.1 0.2 0.1 97.6 140.1 0.6 2.3 0.2 0.5 1072.9 0.0 1527.6 0.1 0.5 0.3 0.1 10.8 7.3 0.0 0.0 0.9 0.6 2232.0 0.5 20.7 0.3 0.3 0.1 0.6 1.1 0.2 140.0 0.7 1.1 0.4 1675.1 1.9 0.6 0.6 2.8 8.1 51.2 0.7 0.7 2.2 1579.1 2.1 36.5 3.9 1.7 0.0 0.7 0.8 1.1 2.0 0.4 0.8 0.9 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.6 1.5 2.0 1.5 1.5 1.5 1.5 1.5 1.4 1.7 1.5 2.7 60.9 162.6 2.3 4.2 2340.8 448.6 770.5 657.9 0.0 256.2 178.3 5.3 270.2 387.7 35.0 0.0 2.7 2.2 1058.2 49.0 197.5 0.0 37.3 6.4 21.5 153.4 0.0 0.0 65.8 1.5 22.8 85.6 80.3 28.0 0.2 1.1 9.5 0.3 0.0 0.0 660.1 126.1 0.3 213.7 0.0 0.0 3.0 241.9 0.0 2.0 0.0 0.0 0.0 0.1 343.0 1098.9 0.0 7.5 619.3 1549.1 4.9 56.2 0.0 0.0 1.3 27.1 0.0 0.0 3205.8 3612.0 0.3 8.7 13.6 580.9 824.9 SERPINB11 EPIPIN ENSG00000206072 "Serpin family B member 11" Q96P15 18 63647579-63726432 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 27.4;prostate: 32.5" "Cell type enhanced" "Detected in some" "Club cells: 6.8;Prostatic glandular cells: 3.3;Respiratory ciliated cells: 4.4;Squamous epithelial cells: 13.7;Urothelial cells: 21.9" "Cancer enriched" "Detected in some" 5 "prostate cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (5.04e-3)" "unprognostic (4.76e-2)" "unprognostic (4.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 32.5 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 9.0 2.9 6.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.2 0.0 0.0 21.9 SERPINB13 "headpin, HUR7, hurpin, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 56.6;esophagus: 180.4;vagina: 135.0" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 58.8;Club cells: 54.8;Squamous epithelial cells: 148.6" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 129 "HaCaT: 198.9;hTCEpi: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 56.6 0.0 0.0 0.0 0.0 0.0 180.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 35.7 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 22.9 3.3 135.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 1.7 1.9 58.8 13.1 0.0 0.0 0.1 0.1 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 8.5 0.0 0.0 0.0 1.0 0.0 0.0 148.6 1.3 0.5 0.0 0.0 0.0 19.9 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SIM2 "bHLHe15, MGC119447, SIM" ENSG00000159263 "SIM bHLH transcription factor 2" Q14190 21 36699115-36749917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 31.1;kidney: 61.3" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 100.7;Squamous epithelial cells: 68.3" "Cancer enhanced" "Detected in many" "prostate cancer: 11.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 24.9;PC-3: 43.0;RPTEC TERT1: 54.3;RT4: 33.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.2" HPA029295 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "HPA029295: AB_10610425" "unprognostic (1.17e-3)" "unprognostic (6.46e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (8.62e-2)" "unprognostic (1.43e-2)" "unprognostic (8.30e-2)" "unprognostic (5.46e-3)" "unprognostic (1.65e-2)" "unprognostic (1.09e-1)" "unprognostic (5.16e-3)" "unprognostic (9.18e-2)" "unprognostic (9.18e-7)" "unprognostic (2.98e-2)" "unprognostic (3.79e-2)" "unprognostic (1.07e-2)" "prognostic favorable (2.88e-4)" 0.3 0.3 1.8 0.0 1.1 0.0 0.4 0.7 1.4 2.3 0.4 0.5 0.0 0.5 0.8 31.1 0.6 0.0 0.2 1.5 2.5 61.3 0.4 0.2 0.0 0.7 1.4 0.2 0.3 1.8 1.6 0.0 0.5 6.6 0.0 0.0 0.6 0.0 10.6 0.5 0.3 0.0 0.5 0.3 9.5 0.4 2.4 0.0 0.4 0.0 3.5 0.7 0.7 0.7 6.4 9.6 0.0 0.3 0.0 0.0 9.4 0.0 0.0 0.9 0.0 5.0 14.7 0.0 8.6 0.2 17.0 3.2 4.8 0.0 0.5 7.8 15.0 0.0 14.3 0.3 0.0 0.0 0.0 1.6 1.4 0.0 2.6 24.9 0.0 0.0 0.0 0.0 16.0 3.7 0.0 0.0 0.0 6.4 43.0 0.0 0.0 0.0 54.3 33.5 0.4 0.0 15.7 0.0 0.9 1.6 4.1 0.0 0.6 0.0 2.5 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.1 0.7 1.4 1.5 2.5 0.7 1.4 0.5 0.5 2.4 0.7 0.2 0.0 0.0 0.0 0.0 0.3 19.1 0.0 100.7 0.2 0.1 0.1 2.0 0.0 0.0 9.2 0.0 0.0 0.0 0.2 9.8 0.1 2.2 0.3 0.3 0.4 0.0 0.0 0.3 0.0 0.0 0.8 12.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 5.8 0.3 0.3 0.0 0.0 0.0 0.0 0.0 7.1 1.1 0.0 0.0 0.0 1.3 9.5 0.1 0.2 0.0 0.5 0.0 1.5 0.9 0.5 0.2 68.3 0.4 0.0 0.4 0.0 0.2 4.0 SLC1A5 "AAAT, ASCT2, M7V1, RDRC" ENSG00000105281 "Solute carrier family 1 member 5" Q15758 19 46774883-46788594 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Host-virus interaction, Symport, Transport" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 148.6;Erythroid cells: 143.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 95.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035239, HPA035240" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA035239: AB_10670587, HPA035240: AB_10604092" "unprognostic (8.26e-3)" "unprognostic (6.38e-2)" "unprognostic (7.24e-2)" "unprognostic (7.94e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.66e-8)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (9.82e-2)" "unprognostic (9.40e-3)" "unprognostic (9.57e-3)" "prognostic unfavorable (1.18e-7)" "unprognostic (1.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.06e-2)" "unprognostic (9.83e-2)" 97.2 15.9 5.8 29.6 6.5 60.9 77.7 6.6 6.1 57.4 6.1 50.1 16.2 39.1 98.0 98.0 48.9 36.5 26.4 5.9 8.5 45.6 8.1 65.3 27.9 15.8 11.1 45.8 73.2 2.9 24.5 46.9 13.3 98.6 42.4 1.4 120.5 77.0 8.5 55.7 36.2 33.0 9.5 40.4 55.5 40.3 9.8 19.9 14.1 10.7 30.3 109.6 83.0 11.5 179.6 323.6 76.3 116.1 194.7 164.3 180.0 249.6 283.0 183.2 264.1 296.1 197.1 194.8 118.9 624.2 105.2 281.1 224.9 296.9 135.5 130.1 203.7 324.3 115.1 281.9 501.3 228.2 182.9 268.6 727.3 215.5 541.1 61.3 98.9 255.0 348.9 500.1 99.5 304.5 105.4 611.1 134.0 636.5 140.9 117.8 86.5 282.7 104.2 384.8 117.3 86.0 123.4 331.8 275.4 58.8 191.6 296.6 74.1 109.4 174.1 86.4 205.7 308.0 325.3 164.0 206.3 281.0 274.3 0.1 36.1 2.9 14.1 55.0 11.4 17.8 8.0 9.9 50.2 8.1 1.9 6.0 1.0 21.0 66.3 95.8 15.5 27.8 5.8 6.5 6.6 6.1 5.9 8.5 15.8 11.1 13.3 9.5 9.8 11.5 63.6 0.0 17.3 0.0 31.1 57.7 148.6 95.9 64.9 0.2 52.0 43.1 20.3 21.5 41.2 0.0 0.0 80.8 86.3 44.6 3.9 38.5 27.0 2.6 32.9 29.0 10.7 143.3 0.6 65.7 129.3 48.0 21.9 2.7 29.2 20.9 29.6 0.7 38.4 0.0 0.8 111.3 40.7 21.6 34.7 14.0 19.0 39.8 19.6 3.7 26.0 0.6 12.3 0.0 0.6 43.4 74.8 19.5 68.6 59.0 6.5 23.1 13.0 0.8 6.6 15.8 44.0 35.9 4.0 69.0 28.3 24.4 38.7 6.1 62.9 100.0 SLC7A1 "ATRC1, CAT-1, ERR, HCAT1, REC1L" ENSG00000139514 "Solute carrier family 7 member 1" P30825 13 29509414-29595688 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 55.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 235.6;Microglial cells: 162.1;Squamous epithelial cells: 175.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039721, HPA077838" Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA039721: AB_10672893, HPA077838: " "unprognostic (1.85e-1)" "unprognostic (1.04e-3)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (3.95e-3)" "unprognostic (2.43e-2)" "unprognostic (1.36e-3)" "unprognostic (2.02e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.20e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (7.37e-3)" 6.2 6.0 34.8 10.7 21.9 11.3 7.7 28.6 31.1 8.5 24.4 10.1 10.2 8.4 10.2 55.1 7.4 4.5 7.5 31.0 25.9 6.6 2.0 4.9 8.6 40.5 27.6 2.8 30.5 4.5 7.5 3.0 41.4 7.7 7.4 9.0 16.1 9.2 2.1 17.7 14.8 9.1 33.9 5.9 11.3 6.9 39.5 7.8 9.6 1.7 10.4 11.0 11.1 27.6 42.2 33.2 28.7 58.0 14.5 28.6 32.6 87.8 58.3 74.2 55.0 68.0 72.1 82.9 23.3 134.5 82.8 188.0 50.4 62.2 97.1 78.3 30.1 62.1 36.3 37.0 75.0 91.6 39.4 36.6 129.4 82.6 96.9 17.4 37.1 92.8 40.5 37.6 31.5 56.5 67.2 24.6 27.5 74.2 22.1 45.7 59.1 48.3 47.2 27.5 97.3 46.3 50.0 48.3 79.4 17.9 21.3 76.6 35.1 58.2 40.6 51.6 63.6 42.1 33.1 93.8 46.4 36.3 60.1 0.0 0.4 0.1 1.0 0.4 0.8 0.6 0.7 0.8 0.6 0.4 0.5 0.9 0.0 0.2 1.0 1.2 0.6 0.7 34.8 21.9 28.6 31.1 31.0 25.9 40.5 27.6 41.4 33.9 39.5 27.6 12.1 0.0 5.0 7.2 14.4 49.8 53.9 33.0 235.6 15.6 21.4 12.8 10.2 12.8 16.2 71.7 16.7 1.1 10.3 14.7 1.9 19.9 0.2 32.5 10.0 29.2 31.1 54.7 28.9 56.9 40.0 10.3 26.5 69.2 7.0 8.0 5.7 0.4 6.1 25.2 27.0 34.5 26.4 5.7 18.2 0.8 6.2 8.6 8.8 162.1 5.7 3.1 3.1 23.6 13.1 56.5 21.1 3.8 36.8 55.2 20.7 0.3 10.1 18.6 6.6 28.1 9.0 4.5 2.1 175.1 34.9 4.0 11.3 10.8 33.5 41.6 SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1039.2;skin 1: 858.5" "Group enriched" "Detected in some" 16 "Squamous epithelial cells: 20.8;Suprabasal keratinocytes: 65.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;MCF7: 1.5;RT4: 1.1;T-47d: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" NA NA 7700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" 0.9 0.6 0.1 0.0 0.0 0.0 11.3 0.7 0.5 105.0 0.0 0.3 0.0 0.2 0.0 1039.2 0.2 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 70.1 0.0 1.4 858.5 0.3 0.0 0.0 0.2 0.8 0.3 0.1 0.9 0.2 0.0 17.4 0.3 206.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.6 0.0 0.0 1.8 1.5 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.8 65.8 0.0 0.0 0.0 0.0 0.8 SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.2;Basal squamous epithelial cells: 447.3;Squamous epithelial cells: 388.1;Suprabasal keratinocytes: 169.9" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Group enriched" "Detected in many" 8 "A-431: 130.6;HaCaT: 142.1;HBEC3-KT: 57.8;hTCEpi: 56.6" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" 2.2 0.9 15.0 0.8 14.6 2.7 3.4 17.4 23.3 21.1 11.8 12.4 0.7 8.2 1.7 87.4 11.0 1.0 8.6 14.5 15.3 1.7 1.3 1.5 0.5 14.3 15.0 15.3 1.0 0.2 7.9 0.3 14.1 12.1 0.5 5.0 14.6 7.1 2.3 48.2 3.5 1.3 14.5 1.1 4.7 2.6 14.7 1.0 2.3 1.8 2.8 10.4 32.7 15.0 130.6 3.2 1.8 1.0 0.1 0.3 9.6 1.4 0.5 1.1 1.7 2.5 0.8 0.4 1.2 0.1 0.4 142.1 0.1 57.8 0.4 3.3 3.9 0.5 1.7 0.5 0.2 0.3 2.6 0.0 56.6 0.7 11.9 3.6 0.0 2.6 2.9 0.8 0.2 0.9 0.6 1.5 3.6 0.3 0.7 1.6 1.8 1.0 2.7 0.7 0.8 2.2 1.5 0.5 0.7 5.5 1.1 1.0 1.6 1.3 2.3 1.6 4.4 0.9 1.5 1.6 4.4 1.7 3.2 0.1 2.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.6 1.0 0.0 0.4 15.0 14.6 17.4 23.3 14.5 15.3 14.3 15.0 14.1 14.5 14.7 15.0 0.8 0.0 0.0 2.6 0.1 209.2 51.8 72.7 447.3 13.6 6.3 13.0 4.7 0.0 20.6 1.8 14.6 1.7 0.7 0.5 1.9 0.1 0.2 0.4 4.9 3.1 1.2 0.0 8.1 0.5 2.0 10.4 0.0 0.4 0.0 1.3 1.4 0.0 0.4 10.1 7.7 0.4 10.2 1.2 19.3 1.1 31.4 0.9 26.6 1.0 1.2 50.0 0.0 4.0 2.4 0.5 0.1 36.9 4.9 21.2 0.3 0.2 16.2 9.4 32.9 7.8 7.1 0.7 10.9 388.1 169.9 1.1 1.1 0.6 0.8 73.8 SOX21 SOX25 ENSG00000125285 "SRY-box transcription factor 21" Q9Y651 13 94709622-94712545 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.8;esophagus: 10.3;skin 1: 15.9;stomach 1: 35.1" "Cell type enhanced" "Detected in some" "Astrocytes: 24.5;Basal squamous epithelial cells: 11.4;Gastric mucus-secreting cells: 55.5;Oligodendrocyte precursor cells: 17.1;Squamous epithelial cells: 57.1" "Cancer enhanced" "Detected in many" "glioma: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 79.7;NTERA-2: 21.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048337, HPA064084" Approved Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA048337: AB_2732547, HPA064084: AB_2685187" "unprognostic (3.33e-1)" "prognostic favorable (7.60e-4)" "unprognostic (7.96e-2)" "prognostic favorable (8.79e-5)" "unprognostic (1.54e-2)" "unprognostic (3.87e-1)" "unprognostic (9.02e-2)" "unprognostic (2.11e-1)" "unprognostic (1.50e-1)" "unprognostic (2.90e-2)" "unprognostic (1.93e-1)" "unprognostic (6.05e-2)" "unprognostic (1.11e-1)" "unprognostic (3.51e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" 0.0 0.0 9.6 0.0 9.7 0.0 0.6 7.3 9.4 0.9 2.7 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 8.6 8.7 0.0 0.0 0.1 0.0 8.1 9.8 0.0 0.0 0.0 0.2 0.0 6.8 0.5 0.0 0.0 1.4 0.0 0.0 15.9 0.0 0.0 8.7 0.0 35.1 0.1 9.8 0.0 0.0 0.0 3.3 0.3 2.2 7.8 0.0 2.4 79.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 6.4 12.3 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 9.7 7.3 9.4 8.6 8.7 8.1 9.8 6.8 8.7 9.8 7.8 0.0 0.0 0.0 24.5 0.0 5.4 1.1 6.6 11.4 0.0 0.0 0.0 1.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 55.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.4 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 17.1 0.3 0.0 0.0 0.0 0.1 1.6 0.0 0.0 2.7 0.0 0.0 0.0 0.3 0.1 0.4 57.1 9.1 0.0 0.0 0.0 0.0 0.9 SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.7;salivary gland: 80.1" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Basal squamous epithelial cells: 166.8;Breast glandular cells: 141.0;Cholangiocytes: 190.1;Gastric mucus-secreting cells: 144.8;Muller glia cells: 141.3;Squamous epithelial cells: 273.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 78.1;Hep G2: 97.0;OE19: 74.3;U-251 MG: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB022456: , CAB068240: AB_2665670, HPA001758: AB_1080067" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (4.47e-3)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (7.96e-3)" "unprognostic (4.32e-3)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.92e-3)" "unprognostic (1.21e-1)" "unprognostic (3.26e-3)" "unprognostic (2.77e-3)" "unprognostic (1.15e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-2)" 3.1 2.2 54.7 4.4 50.4 0.1 28.0 42.3 58.5 7.4 46.8 17.1 19.7 2.9 0.9 13.7 7.5 13.0 15.8 50.6 49.3 12.7 3.5 3.1 1.1 73.7 72.2 0.3 38.4 0.1 10.3 0.3 48.8 24.8 17.8 15.0 80.1 10.9 2.7 23.3 15.1 1.2 56.9 0.2 40.5 30.7 51.4 0.5 20.2 1.2 4.4 1.9 6.4 49.0 31.1 19.2 38.9 78.1 3.9 1.1 0.1 4.8 4.2 8.2 4.4 27.0 40.8 0.0 2.9 1.1 43.8 31.3 0.0 18.6 7.5 0.0 2.5 0.0 4.2 97.0 0.3 0.0 0.1 0.7 1.6 9.5 9.0 47.0 0.0 0.0 0.0 0.1 11.7 0.4 0.0 0.1 1.5 74.3 29.1 0.0 31.4 0.4 35.2 2.0 1.9 1.9 4.0 4.7 0.1 21.0 16.7 0.2 0.0 15.8 42.0 8.5 66.5 0.0 0.0 0.1 11.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.4 42.3 58.5 50.6 49.3 73.7 72.2 48.8 56.9 51.4 49.0 1.1 12.8 5.6 160.0 1.9 55.4 88.2 28.9 166.8 3.0 141.0 108.2 13.6 190.1 21.1 36.8 0.0 0.3 2.8 52.1 7.9 55.3 5.1 18.4 0.9 3.2 59.7 0.0 3.1 46.7 0.0 26.0 144.8 21.7 4.5 1.9 0.0 3.4 0.2 0.0 1.5 99.0 24.4 0.0 3.4 14.5 4.4 2.3 12.4 9.4 1.0 141.3 0.0 4.5 11.1 40.8 39.1 0.4 2.8 81.1 17.7 61.0 36.4 6.8 6.6 59.9 14.5 10.2 3.1 273.5 17.8 0.1 2.8 0.1 103.8 77.2 SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 338.5;esophagus: 1015.0;skin 1: 318.2;vagina: 582.6" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 1622.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 14.7;HeLa: 22.7;Karpas-707: 19.3;SuSa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" NA NA 43000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" 1.1 0.3 0.0 0.5 0.1 0.0 17.5 0.0 0.2 338.5 0.0 4.8 0.3 0.6 0.3 1015.0 0.4 1.8 1.7 0.1 0.0 0.8 0.4 2.0 0.1 0.1 0.1 0.3 0.8 1.0 2.0 2.4 0.2 1.3 10.6 0.0 145.0 0.5 1.8 318.2 0.6 0.4 0.0 0.3 5.0 1.6 0.1 9.1 2.2 1.1 292.9 0.7 582.6 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 1.8 0.0 0.0 14.7 0.0 1.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.3 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.0 0.9 19.3 0.0 2.1 0.0 0.0 2.6 2.0 0.3 0.0 0.0 0.0 0.0 5.7 2.8 0.0 0.6 0.0 0.0 6.6 4.6 0.0 0.0 0.0 0.1 0.0 0.0 5.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 5.7 9.6 45.4 0.3 0.2 53.7 1.5 331.1 102.4 0.0 4.2 3.4 1.2 34.3 115.6 0.0 0.0 1.9 0.0 177.9 0.0 0.2 11.0 2.5 0.7 12.9 4.2 0.0 0.7 1.3 2.1 2.6 17.9 4.8 1.3 0.0 7.9 0.2 0.1 0.0 0.8 33.8 16.2 0.8 2.1 3.8 0.6 0.7 3.6 2.8 0.0 0.0 0.0 2.0 1.2 7.6 60.3 0.0 3.7 0.7 0.0 0.0 9.4 0.0 0.0 0.2 2.4 1.3 4.6 1622.6 64.4 1.5 1.1 1.0 97.9 2.7 SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 256.8;esophagus: 620.4;vagina: 614.0" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 49.2" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" NA NA 230000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.3 256.8 0.1 0.1 0.0 0.1 0.1 620.4 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.7 0.0 0.3 0.1 0.0 0.0 140.1 0.0 0.2 9.3 0.1 0.1 0.1 0.1 4.2 0.1 0.2 4.7 0.1 0.1 115.9 0.6 614.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 0.0 0.0 0.0 0.0 0.0 4.5 SPRR2A ENSG00000241794 "Small proline rich protein 2A" P35326 1 153056120-153057512 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 5262.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 37.6;Club cells: 23.0;Ductal cells: 20.6;Exocrine glandular cells: 57.1;Squamous epithelial cells: 82.3" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 743.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 6.4;hTCEpi: 7.8;hTERT-HME1: 10.3;Karpas-707: 12.6" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (3.15e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-3)" "unprognostic (1.64e-2)" "unprognostic (6.80e-3)" "unprognostic (3.51e-1)" "unprognostic (3.36e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.37e-5)" 1.6 0.9 0.0 0.0 0.0 0.1 0.9 0.0 0.1 1144.4 0.0 0.6 0.0 0.8 0.0 5262.1 0.8 7.8 1.7 0.0 0.0 1.4 1.8 0.6 0.0 0.0 0.0 1.6 2.1 0.0 1.2 0.0 0.0 0.6 0.0 0.0 1135.0 0.0 1.7 28.2 0.8 0.6 0.0 0.9 2.9 0.8 0.0 0.8 0.5 0.0 763.9 1.0 1226.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 7.8 0.0 10.3 0.0 0.0 0.0 0.8 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 2.5 0.3 0.6 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.5 0.1 37.6 0.6 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 57.1 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.6 0.0 0.0 82.3 11.8 0.0 0.0 0.4 0.0 2.1 SPRR2E ENSG00000203785 "Small proline rich protein 2E" P22531 1 153093135-153106184 "Predicted intracellular proteins" Keratinization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 1773.2;skin 1: 1179.2" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 26.2;Granulosa cells: 21.2;Squamous epithelial cells: 18.4;Suprabasal keratinocytes: 43.8" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 612.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "hTCEpi: 16.5" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (2.27e-1)" "unprognostic (3.86e-2)" "unprognostic (5.04e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (9.47e-4)" 2.7 0.5 0.0 0.0 0.0 0.3 46.0 0.0 0.0 337.6 0.0 0.4 0.0 0.4 0.0 1773.2 0.3 0.4 0.8 0.0 0.0 0.4 1.0 0.4 0.0 0.0 0.0 2.3 1.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 338.7 0.0 1.2 1179.2 0.4 0.4 0.0 0.3 1.0 0.6 0.0 1.9 0.3 0.0 503.5 0.3 482.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 16.5 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.2 18.4 43.8 0.0 0.1 0.1 0.0 0.0 SPRR3 ENSG00000163209 "Small proline rich protein 3" Q9UBC9 1 153001747-153003856 "Cancer-related genes, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 4257.2;esophagus: 19480.4;vagina: 6062.0" "Cell type enriched" "Detected in some" 11 "Squamous epithelial cells: 987.1" "Group enriched" "Detected in many" 4 "cervical cancer: 206.3;head and neck cancer: 423.4;stomach cancer: 113.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.5;CAPAN-2: 5.8;hTCEpi: 9.7;OE19: 4.4;RT4: 12.6;TIME: 3.4" "Not detected" "Not detected" HPA044467 Enhanced NA NA 5200 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA044467: AB_2678952" "unprognostic (2.78e-2)" "unprognostic (3.54e-1)" "unprognostic (8.77e-2)" "unprognostic (7.50e-3)" "unprognostic (9.67e-3)" "unprognostic (2.36e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (9.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.58e-2)" 4.0 3.5 0.0 0.1 0.0 0.0 3.0 0.0 0.0 4257.2 0.0 2.6 0.1 3.5 0.0 19480.4 3.4 38.1 7.4 0.0 0.0 2.6 5.8 1.7 0.0 0.0 0.0 4.4 8.8 0.0 11.0 0.7 0.0 3.4 0.1 0.0 3157.9 0.0 5.0 7.5 4.2 1.7 0.0 3.4 15.2 2.1 0.0 1.4 2.3 0.0 2399.3 65.1 6062.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 3.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.3 0.0 0.0 0.0 4.4 0.0 0.0 1.1 0.0 0.0 12.6 0.0 0.0 0.3 2.7 0.0 0.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 1.5 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 4.0 7.4 0.0 0.0 0.0 0.1 0.0 41.3 0.0 0.0 5.9 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 4.2 1.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.3 0.0 0.0 0.0 0.4 0.0 0.1 2.1 0.0 0.0 0.0 1.0 0.0 0.0 987.1 0.0 7.5 0.4 0.1 0.0 89.6 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 1.5 2.0 4.7 1.9 5.3 2.2 11.0 7.4 8.8 3.9 0.1 2.4 4.1 1.7 3.0 11.0 1.7 1.7 1.0 5.5 3.2 4.6 29.0 1.9 2.3 6.0 3.3 2.5 2.3 1.4 1.1 1.0 6.3 1.5 2.3 3.8 2.7 1.1 1.3 13.6 4.1 1.6 1.8 1.4 2.5 1.5 6.9 1.6 1.3 0.7 4.1 1.1 6.6 8.3 5.2 6.1 8.0 6.7 7.6 7.3 3.5 5.7 4.5 5.7 3.5 6.0 5.3 7.1 8.1 8.7 9.1 9.8 6.6 4.0 6.0 4.3 2.6 2.2 15.3 3.7 3.4 3.3 1.8 5.4 11.3 4.1 3.2 4.2 2.9 2.7 3.7 6.2 7.5 7.1 1.4 3.6 4.5 4.1 4.7 5.1 5.8 2.0 7.6 5.4 14.0 6.4 18.2 7.6 5.8 6.1 2.6 0.9 5.8 8.6 3.4 14.2 7.6 2.3 3.6 2.6 7.2 3.6 8.0 3.5 1.3 0.5 0.3 1.0 0.2 0.5 0.3 0.5 1.6 0.6 0.2 0.3 0.7 0.5 1.1 0.7 0.4 0.5 4.7 5.3 7.4 8.8 5.5 3.2 6.0 3.3 6.3 1.8 6.9 8.3 3.7 3.2 2.7 7.8 11.9 18.5 6.7 19.0 67.2 5.0 14.5 9.1 2.6 11.5 12.8 5.5 4.2 0.9 5.0 8.3 7.9 9.8 8.1 2.6 4.3 3.2 2.4 4.4 15.5 4.7 7.4 4.7 16.3 3.2 1.3 6.0 4.6 103.4 13.0 6.7 14.9 7.2 52.9 19.4 11.6 2.6 3.4 11.6 7.2 6.5 50.7 5.1 10.3 9.0 7.6 6.7 10.4 7.9 7.2 9.4 24.9 23.4 10.4 3.8 0.0 3.7 6.1 3.4 4.4 139.2 30.4 0.8 5.9 5.2 12.0 10.2 SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.2;skin 1: 65.5;urinary bladder: 40.5" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 184.7;Basal squamous epithelial cells: 520.2;Breast myoepithelial cells: 192.9;Cholangiocytes: 183.0;Extravillous trophoblasts: 201.8;Respiratory ciliated cells: 163.8;Squamous epithelial cells: 132.5" "Group enriched" "Detected in many" 5 "cervical cancer: 10.5;pancreatic cancer: 21.7;urothelial cancer: 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 32.2;hTCEpi: 50.2;T-47d: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047239, HPA052700" Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA047239: , HPA052700: AB_2681920" "unprognostic (1.66e-3)" "unprognostic (2.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "unprognostic (6.31e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (1.36e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (7.09e-2)" "unprognostic (2.48e-1)" "unprognostic (2.33e-6)" "unprognostic (2.87e-2)" "unprognostic (1.75e-1)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" 0.1 0.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 1.3 0.1 0.4 0.5 0.0 0.5 29.2 1.0 8.6 0.0 0.0 0.0 0.3 0.6 4.7 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.6 0.0 2.5 0.0 0.0 20.9 2.9 0.0 65.5 2.5 0.0 0.0 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.1 40.5 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 32.2 0.0 0.0 0.0 0.6 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 50.2 0.0 5.8 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.7 0.0 0.0 0.3 0.0 0.1 1.0 0.0 0.3 0.0 2.7 0.0 0.0 13.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 16.0 3.9 0.0 0.3 184.7 5.6 24.9 520.2 0.0 3.2 192.9 0.6 183.0 39.1 5.5 0.0 28.7 0.7 3.4 0.0 31.1 0.0 15.6 0.1 1.7 0.0 0.0 0.0 9.7 201.8 1.6 12.2 0.6 1.3 0.0 0.0 0.1 7.1 0.0 0.0 1.3 16.2 0.0 14.7 0.0 0.0 1.3 10.6 0.0 0.0 0.0 0.0 0.0 0.0 28.3 3.5 0.0 6.2 1.3 18.3 0.0 163.8 0.0 0.0 0.0 7.0 0.0 0.0 132.5 47.2 36.8 0.6 0.1 1.7 31.5 SYTL1 "exophilin-7, FLJ14996, JFC1, SLP1" ENSG00000142765 "Synaptotagmin like 1" Q8IYJ3 1 27342020-27353937 "Plasma proteins, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.9;pancreas: 106.3;skin 1: 87.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 158.8;NK-cells: 208.1;Squamous epithelial cells: 179.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 4.3;cerebellum: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 47.8;CAPAN-2: 55.8;NB-4: 81.8;U-266/70: 44.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA037825 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA037825: AB_10671635" "unprognostic (4.23e-2)" "unprognostic (8.23e-2)" "unprognostic (2.40e-1)" "prognostic favorable (6.83e-7)" "unprognostic (7.81e-3)" "unprognostic (5.81e-2)" "unprognostic (1.05e-1)" "unprognostic (7.18e-3)" "unprognostic (4.41e-1)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.45e-1)" "unprognostic (3.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-3)" 2.0 0.6 4.3 19.1 0.7 46.7 7.7 8.8 1.4 22.6 6.1 6.7 7.8 1.3 1.2 103.9 15.5 8.6 0.9 1.0 1.0 2.8 2.1 13.1 32.9 0.7 0.8 0.6 106.3 4.2 15.6 2.9 0.8 63.6 3.3 0.0 47.6 12.7 0.5 87.2 17.6 0.4 0.5 42.0 41.8 0.9 1.2 21.4 9.8 0.5 20.0 21.6 50.9 0.6 11.3 0.2 0.0 0.4 0.0 0.0 47.8 0.0 0.0 0.0 0.0 1.2 55.8 8.5 10.9 0.0 0.3 34.7 0.0 21.0 0.0 0.0 2.1 1.0 0.9 15.3 0.8 21.9 0.0 0.0 37.8 0.0 7.8 0.2 0.0 28.2 0.7 9.5 0.0 15.5 12.9 81.8 0.5 19.1 5.7 14.9 0.1 40.2 8.6 9.6 15.9 0.9 0.0 15.9 0.6 0.5 40.4 23.3 0.2 0.1 5.1 0.0 0.0 44.3 11.7 8.0 1.6 27.7 0.0 47.0 18.9 176.5 65.0 49.1 58.4 42.8 51.5 53.2 51.0 32.3 30.6 37.3 34.1 49.0 100.8 3.0 63.4 40.0 4.3 0.7 8.8 1.4 1.0 1.0 0.7 0.8 0.8 0.5 1.2 0.6 1.9 22.4 13.6 0.0 68.6 41.2 78.2 84.4 158.8 0.6 33.6 49.8 3.9 8.6 69.2 0.0 0.0 37.4 92.3 4.8 7.9 3.7 0.8 67.8 2.4 2.3 11.4 15.8 0.3 25.5 10.1 3.1 100.9 18.3 1.3 0.2 2.2 1.1 3.2 0.0 0.3 47.6 32.6 6.7 12.7 0.7 0.3 15.7 10.6 0.0 18.8 2.0 208.1 0.0 0.1 12.1 3.7 0.7 52.3 46.8 3.1 6.4 62.8 0.8 0.0 1.3 5.6 30.3 23.1 179.1 55.3 14.1 74.9 0.2 9.4 95.3 TBX6 ENSG00000149922 "T-box transcription factor 6" O95947 16 30085793-30091924 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 8.4;Urothelial cells: 9.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "OE19: 4.1;RT4: 6.9;U-266/70: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062498 Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA062498: AB_2732686" "unprognostic (2.47e-1)" "unprognostic (1.32e-3)" "unprognostic (5.62e-5)" "unprognostic (1.49e-1)" "unprognostic (4.76e-2)" "unprognostic (2.35e-2)" "unprognostic (3.35e-1)" "unprognostic (5.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (3.87e-1)" "unprognostic (2.76e-2)" "unprognostic (2.95e-1)" "unprognostic (4.21e-2)" "unprognostic (5.05e-3)" "unprognostic (4.26e-2)" 1.1 1.9 3.3 0.7 3.9 0.5 1.4 3.1 4.1 3.6 2.4 1.8 1.2 1.1 0.7 13.8 1.7 0.8 1.3 3.1 3.3 3.2 1.9 1.4 0.8 3.7 3.7 1.8 4.3 1.0 1.9 0.3 3.9 3.3 0.3 1.7 2.8 1.2 2.0 3.5 1.7 0.4 3.4 2.4 4.7 1.8 4.0 0.9 2.8 0.5 1.5 4.4 7.3 4.5 0.6 0.7 0.4 0.7 1.0 0.5 0.5 0.2 0.1 0.0 0.1 0.9 2.9 1.2 1.5 0.1 0.1 0.8 0.3 0.5 0.0 0.9 0.5 0.8 1.4 0.7 0.7 0.1 1.7 0.2 0.8 0.1 0.3 0.6 0.4 2.7 0.1 2.9 0.0 2.6 0.5 0.3 0.6 4.1 0.6 2.0 0.0 2.1 0.0 6.9 0.9 1.3 0.1 0.5 0.8 0.3 1.2 1.2 0.3 0.8 0.4 0.4 0.0 6.9 1.7 0.2 0.8 1.2 0.2 1.2 0.6 0.2 0.4 0.6 0.3 0.3 0.2 0.3 0.3 1.2 0.4 0.4 0.8 0.3 0.2 0.2 0.5 0.3 3.3 3.9 3.1 4.1 3.1 3.3 3.7 3.7 3.9 3.4 4.0 4.5 1.0 0.0 0.6 2.6 2.7 1.1 3.4 4.2 4.0 1.9 1.2 1.4 0.5 0.0 3.7 1.8 8.4 1.7 0.5 0.7 0.0 0.8 0.1 0.9 0.8 1.9 0.0 3.2 0.2 1.2 0.8 1.1 3.6 1.0 0.0 1.1 0.4 0.4 0.5 0.0 0.4 1.2 4.1 0.8 1.7 0.2 0.9 1.2 0.0 1.9 0.6 1.9 2.1 0.0 2.7 3.5 1.6 1.2 0.2 3.2 2.6 0.7 3.0 3.4 6.6 2.7 1.4 2.6 3.9 6.2 1.0 2.3 0.8 0.5 1.6 9.4 TGM3 TGE ENSG00000125780 "Transglutaminase 3" Q08188 20 2296001-2341079 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "esophagus: 1838.1" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 46.2;Squamous epithelial cells: 22.5" "Cancer enriched" "Detected in many" 9 "head and neck cancer: 81.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 295 "neutrophil: 30.3" "Lineage enriched" "Detected in single" 303 "granulocytes: 30.3" "Cell line enriched" "Detected in single" 14 "EFO-21: 5.2" HPA004728 Approved NA NA 14000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA004728: AB_1080360" "unprognostic (7.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.18e-2)" "unprognostic (3.23e-3)" "unprognostic (4.27e-2)" "unprognostic (4.20e-2)" "unprognostic (8.62e-2)" "unprognostic (4.21e-2)" "unprognostic (1.50e-1)" "unprognostic (8.00e-2)" "unprognostic (4.88e-3)" "unprognostic (1.35e-1)" "unprognostic (7.78e-8)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (9.67e-2)" 0.6 0.3 0.2 0.2 0.0 1.4 3.9 0.0 0.1 54.3 0.0 0.3 0.0 0.2 0.8 1838.1 1.4 2.2 0.4 0.2 0.0 0.2 0.8 0.5 0.0 0.1 0.3 0.3 1.1 0.0 1.6 0.1 0.1 0.6 0.8 0.0 229.3 0.0 0.4 83.1 0.4 0.0 0.1 0.4 2.2 2.0 0.0 0.1 0.1 0.0 142.9 0.3 31.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 1.9 4.0 0.1 0.1 46.2 0.0 0.4 0.0 0.0 0.3 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.2 3.7 0.0 0.0 0.3 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.2 0.0 0.0 0.0 0.1 1.2 0.5 22.5 8.2 0.0 0.0 0.1 0.3 0.2 THOC3 "MGC5469, TEX1" ENSG00000051596 "THO complex 3" Q96J01 5 175917873-176034680 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 132.1;Early spermatids: 187.0;Squamous epithelial cells: 226.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042764, HPA044009, HPA045071" Approved Enhanced Nucleoplasm,Vesicles No No "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm Vesicles "HPA042764: AB_10965055, HPA044009: AB_10959603, HPA045071: AB_10959461" "unprognostic (1.13e-1)" "unprognostic (1.44e-1)" "unprognostic (1.85e-3)" "unprognostic (6.48e-3)" "unprognostic (8.60e-2)" "unprognostic (3.57e-2)" "unprognostic (3.06e-3)" "unprognostic (2.02e-2)" "unprognostic (3.41e-2)" "unprognostic (1.11e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-2)" "unprognostic (8.80e-3)" "unprognostic (3.20e-1)" "unprognostic (2.86e-1)" "unprognostic (3.16e-2)" "unprognostic (2.91e-1)" 12.0 14.5 22.0 11.4 15.9 35.1 21.4 23.0 40.6 23.1 19.1 27.0 12.5 13.4 63.2 82.9 15.1 8.0 9.3 40.2 14.9 16.3 22.2 11.9 29.1 15.5 13.3 18.8 15.3 10.0 15.9 17.4 15.9 14.6 21.1 12.1 22.5 14.9 12.6 26.5 16.2 12.2 13.2 17.7 17.5 51.3 15.4 39.2 20.5 17.6 45.5 17.4 33.5 15.9 82.1 44.7 47.0 102.7 44.1 39.3 168.0 48.4 44.6 104.5 120.4 63.5 65.2 105.6 68.3 27.9 112.6 69.2 71.6 206.0 109.7 73.5 103.3 57.3 46.2 70.7 14.6 94.6 49.2 33.3 85.9 90.0 45.2 23.3 58.3 98.0 88.1 46.5 66.9 98.7 64.0 57.9 40.1 82.3 160.3 110.7 59.3 110.4 75.2 60.7 89.5 51.4 100.0 48.5 52.5 67.4 55.3 86.1 45.1 35.9 40.8 55.6 88.2 23.2 44.1 64.4 26.7 90.1 28.5 16.5 26.9 15.1 39.3 33.5 48.4 49.6 81.7 48.9 43.1 70.6 99.7 62.4 3.9 42.3 31.5 39.8 133.6 59.1 22.0 15.9 23.0 40.6 40.2 14.9 15.5 13.3 15.9 13.2 15.4 15.9 14.9 12.8 8.6 2.0 35.8 44.5 34.1 64.5 132.1 12.3 17.7 18.0 4.0 10.0 24.4 25.8 10.4 40.8 25.1 8.1 41.1 25.1 187.0 50.2 18.4 16.1 16.8 63.9 5.2 19.2 84.3 15.2 26.5 44.9 12.0 18.8 13.9 20.3 24.6 6.7 3.7 16.3 26.4 13.2 14.9 122.0 14.6 14.3 8.8 1.9 15.4 8.9 27.8 4.5 2.0 21.9 11.6 19.2 55.9 18.4 10.4 46.8 15.8 12.0 19.7 10.6 22.8 107.9 48.3 226.5 40.9 20.0 33.3 25.0 27.7 31.1 THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 103.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 106.4;Basal squamous epithelial cells: 449.0;Microglial cells: 247.3;Squamous epithelial cells: 141.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 45.3;BJ hTERT+: 53.0;T-47d: 43.3;TIME: 66.6;U-2197: 44.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.0" "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" 4.8 8.4 9.8 1.6 7.8 0.0 14.7 6.1 8.6 103.7 9.5 7.0 7.9 22.2 7.8 60.3 37.0 10.9 41.6 8.5 7.2 14.2 7.0 10.3 0.9 7.8 9.1 3.1 6.4 0.7 9.7 3.6 7.6 34.0 6.9 1.2 11.4 15.0 3.0 8.5 8.7 10.3 7.0 1.9 12.0 3.1 15.9 1.6 8.8 2.5 2.5 13.3 38.5 5.9 6.0 45.3 0.8 13.0 6.7 40.2 0.2 22.0 53.0 11.2 5.8 0.3 8.7 0.0 17.7 7.8 38.5 17.0 1.8 9.1 6.8 2.0 2.0 0.0 4.4 0.0 4.3 0.0 0.0 3.0 6.7 6.7 26.6 30.5 20.7 0.0 0.0 0.5 9.2 9.1 0.0 0.1 3.9 0.1 7.8 0.0 0.7 0.8 29.5 6.0 0.7 5.5 8.8 10.9 0.0 5.0 43.3 0.1 66.6 0.2 1.0 44.4 11.8 0.0 0.3 0.0 10.4 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 7.8 6.1 8.6 8.5 7.2 7.8 9.1 7.6 7.0 15.9 5.9 1.1 19.2 9.0 6.5 0.0 13.9 106.4 11.3 449.0 3.0 48.7 43.9 60.1 58.6 7.5 5.5 6.2 0.4 0.8 16.2 1.9 18.3 7.5 19.3 13.2 9.8 3.0 0.0 17.1 1.8 0.4 12.5 2.6 31.8 0.0 0.3 6.1 12.3 0.2 0.0 19.1 6.1 0.0 0.0 2.1 16.9 17.4 1.6 8.8 247.3 0.0 0.3 0.0 8.5 6.7 13.6 11.0 74.4 1.2 94.6 29.3 0.5 11.0 0.9 0.0 16.8 6.6 0.9 1.7 141.5 10.9 0.8 3.1 42.2 13.2 29.7 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM69 "C1orf154, FLJ21029" ENSG00000159596 "Transmembrane protein 69" Q5SWH9 1 45688181-45694436 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026993 Approved Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA026993: AB_10601824" "prognostic favorable (2.24e-4)" "unprognostic (2.47e-1)" "unprognostic (5.25e-2)" "unprognostic (1.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.66e-8)" "unprognostic (4.05e-2)" "unprognostic (1.59e-3)" "unprognostic (5.17e-2)" "unprognostic (3.98e-3)" "unprognostic (1.98e-1)" "unprognostic (1.14e-3)" "unprognostic (1.49e-2)" "unprognostic (1.96e-1)" "unprognostic (4.41e-3)" "unprognostic (3.65e-2)" 17.4 19.5 12.0 17.2 12.4 9.4 21.0 13.2 14.4 14.6 15.6 19.0 22.7 15.6 26.7 21.5 17.1 15.8 31.8 12.4 12.9 16.3 19.4 12.1 26.9 12.6 13.0 23.5 14.0 31.9 5.9 19.7 13.0 19.1 22.9 16.6 21.2 15.4 23.9 21.2 17.0 13.9 12.4 16.2 15.2 13.3 13.0 21.2 21.1 25.4 27.7 26.0 8.7 13.3 50.1 13.2 33.9 25.9 25.1 32.6 81.6 31.6 37.1 52.5 50.7 34.2 24.8 59.8 20.4 30.9 38.1 64.9 26.5 77.2 56.3 40.1 31.6 126.2 30.6 38.2 45.3 59.6 58.2 38.8 75.5 50.7 32.6 34.3 44.7 57.8 75.5 37.4 32.4 17.9 32.9 41.3 77.8 30.0 33.4 51.1 29.2 59.9 56.7 57.2 36.8 34.6 32.8 88.8 56.2 61.2 47.0 59.1 32.5 23.9 40.0 49.8 38.9 29.9 41.6 44.8 32.5 43.0 36.5 12.2 25.0 10.2 9.0 25.8 11.7 16.6 12.8 10.5 22.1 15.5 14.5 11.4 9.6 9.2 34.6 12.5 12.8 13.6 12.0 12.4 13.2 14.4 12.4 12.9 12.6 13.0 13.0 12.4 13.0 13.3 10.8 0.0 14.9 9.8 22.4 20.1 22.8 49.2 37.5 11.0 19.1 21.7 9.1 12.8 26.8 18.4 0.0 61.4 7.7 16.7 43.0 22.7 1.9 13.4 12.6 14.3 24.0 32.4 9.1 17.8 36.1 17.1 35.7 11.6 6.3 12.1 14.6 14.4 37.7 6.7 9.7 21.3 34.6 38.9 11.9 4.4 18.6 21.8 17.8 2.8 23.9 14.5 14.4 9.5 14.6 14.8 16.1 12.8 16.3 22.7 31.0 39.0 18.8 9.8 13.1 10.8 13.0 21.7 16.9 53.5 26.0 59.7 13.7 16.3 25.0 22.4 TMEM79 "FLJ16057, FLJ32254, MATT, MGC13102" ENSG00000163472 "Transmembrane protein 79" Q9BSE2 1 156282935-156293185 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 132.4;skin 1: 89.9;vagina: 59.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 24.1;Squamous epithelial cells: 59.9;Suprabasal keratinocytes: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 30.2;SK-BR-3: 26.7;T-47d: 28.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA055214 Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center" "HPA055214: AB_2682741" "unprognostic (3.12e-1)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (8.17e-2)" "unprognostic (5.51e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (6.37e-2)" "unprognostic (2.44e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.98e-2)" "unprognostic (2.37e-1)" 2.1 2.8 5.5 1.5 6.3 2.9 4.5 6.2 7.5 34.5 5.1 2.4 2.6 2.4 2.6 132.4 2.5 1.8 1.8 5.2 5.7 2.4 3.6 1.9 2.9 6.2 6.2 2.4 2.1 6.0 3.7 1.6 6.0 28.4 1.3 1.7 23.5 2.6 2.9 89.9 2.7 1.2 5.8 3.8 2.9 2.0 6.1 3.6 2.2 0.7 10.9 6.9 59.4 7.8 12.5 7.2 2.4 4.7 1.8 1.8 5.9 3.5 1.4 6.2 2.4 8.5 3.4 2.2 7.6 0.9 2.2 10.8 2.8 5.1 2.7 8.3 3.9 2.3 3.3 2.5 3.3 2.6 3.3 1.7 30.2 4.6 4.7 4.4 1.4 8.2 10.5 14.8 2.9 14.1 7.3 4.0 3.6 9.0 5.7 8.5 2.3 5.0 1.3 3.0 4.3 4.7 4.3 26.7 7.0 2.9 28.3 7.4 3.4 11.5 3.8 4.2 9.5 11.3 13.0 5.2 8.0 6.0 8.8 0.0 2.0 3.0 1.7 0.7 1.8 1.7 1.5 1.8 1.6 2.2 2.0 2.4 3.7 1.7 1.3 2.0 2.1 1.7 5.5 6.3 6.2 7.5 5.2 5.7 6.2 6.2 6.0 5.8 6.1 7.8 1.8 3.2 1.5 8.8 3.9 13.3 1.4 24.1 9.1 3.0 10.0 6.5 1.2 2.8 14.3 1.8 2.1 7.7 3.6 2.4 1.9 2.5 0.1 3.7 2.4 2.0 3.0 0.8 1.8 3.3 1.8 2.1 1.5 6.7 0.0 3.1 2.2 2.4 3.4 8.4 2.2 2.9 10.2 2.5 1.8 0.3 1.5 1.4 5.4 3.7 4.4 1.5 1.0 2.5 5.8 4.5 2.1 0.7 1.6 10.7 4.3 1.6 4.2 2.2 0.0 1.0 1.9 1.3 2.1 59.9 33.1 7.4 3.2 2.9 3.1 6.4 TMPRSS11A "ECRG1, HATL1, HESP" ENSG00000187054 "Transmembrane serine protease 11A" Q6ZMR5 4 67909395-67964140 "Enzymes, Predicted membrane proteins, Transporters" "Cell cycle" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 86.1;lymphoid tissue: 28.4;vagina: 41.7" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 50.7" "Group enriched" "Detected in some" 9 "cervical cancer: 14.4;head and neck cancer: 11.6;lung cancer: 4.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078316 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA078316: " "unprognostic (1.63e-1)" "unprognostic (4.60e-2)" "unprognostic (1.76e-2)" "unprognostic (6.98e-2)" "unprognostic (1.98e-1)" "unprognostic (2.66e-1)" "unprognostic (4.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (3.50e-1)" "unprognostic (2.33e-2)" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.3 19.9 0.0 0.0 0.0 0.0 0.0 86.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.4 12.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.0 0.0 28.4 0.3 41.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.3 0.2 0.3 0.9 0.4 1.1 0.1 0.3 0.7 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.5 1.2 0.6 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.7 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.9 0.0 0.3 0.1 0.1 0.2 50.7 0.0 0.0 0.0 0.0 0.0 7.2 TMPRSS11B HATL5 ENSG00000185873 "Transmembrane serine protease 11B" Q86T26 4 68226653-68245694 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 390.7;lymphoid tissue: 82.2;vagina: 118.3" "Group enriched" "Detected in some" 22 "Early spermatids: 10.4;Late spermatids: 14.5;Squamous epithelial cells: 8.2" "Group enriched" "Detected in some" 12 "cervical cancer: 2.6;head and neck cancer: 2.6;stomach cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (4.24e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.92e-1)" "unprognostic (3.96e-1)" 0.1 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.2 56.8 0.1 0.0 0.0 0.0 0.0 390.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 58.6 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.2 0.0 0.0 0.0 82.2 0.0 118.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 8.2 0.0 0.0 0.1 0.0 0.0 0.2 TMPRSS11F "FLJ16046, HATL4" ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129869 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 15.2;skin 1: 9.3;vagina: 4.8" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 6.9" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "K-562: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026911 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.5 0.1 0.0 0.1 1.0 0.0 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 4.1 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.3 0.1 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 6.9 0.0 0.3 0.0 0.1 0.0 0.5 TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" 5.9 4.4 3.6 3.8 3.8 1.7 6.7 5.8 4.7 5.6 2.1 4.5 5.4 6.4 5.2 9.1 3.9 5.7 3.8 3.9 4.6 8.1 9.0 5.2 2.9 3.4 3.9 5.3 3.2 6.2 2.8 10.2 4.1 7.4 4.7 7.9 3.8 6.3 1.7 12.5 4.4 9.2 3.2 3.9 3.8 4.1 3.6 4.0 6.3 4.3 4.5 6.8 4.7 4.1 13.2 14.0 12.6 11.9 28.8 25.4 22.5 28.1 26.6 15.8 16.9 20.3 9.2 4.1 5.0 25.8 9.6 28.9 13.5 22.4 26.5 2.4 10.2 4.0 9.5 9.3 15.0 4.3 2.5 21.7 12.0 30.5 12.0 16.2 24.9 3.4 8.9 1.4 17.8 7.9 3.0 5.5 9.7 5.0 7.3 2.6 27.4 4.1 13.7 21.3 10.7 10.6 22.8 16.1 7.3 13.3 25.9 4.3 26.4 21.8 12.0 19.4 13.7 4.5 6.3 4.7 6.8 5.0 16.5 7.4 1.3 2.3 1.8 1.1 2.2 2.3 2.0 1.4 0.9 1.8 2.4 2.0 1.3 1.2 1.6 0.9 1.7 0.7 3.6 3.8 5.8 4.7 3.9 4.6 3.4 3.9 4.1 3.2 3.6 4.1 15.9 12.8 8.2 19.6 6.9 34.2 24.4 29.1 24.5 12.5 11.4 8.1 11.1 5.7 20.0 7.3 27.1 29.6 3.5 6.7 3.9 14.5 26.8 23.7 22.2 16.9 3.6 9.5 51.6 10.8 18.2 23.8 8.6 21.9 9.5 12.4 15.7 19.2 8.2 13.5 46.8 5.9 75.3 5.9 6.0 18.2 20.2 3.7 8.8 20.6 2.8 8.3 2.1 28.1 42.4 12.4 4.9 19.5 4.6 18.0 7.3 13.9 34.9 23.4 19.7 17.1 22.3 12.0 8.7 32.6 40.5 17.8 5.2 14.1 7.1 14.4 TNFSF18 "AITRL, hGITRL, TL6" ENSG00000120337 "TNF superfamily member 18" Q9UNG2 1 173039960-173050963 "Predicted intracellular proteins" "Adaptive immunity, Immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "gallbladder: 1.8" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 13.6;Hofbauer cells: 6.4;Squamous epithelial cells: 6.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "EFO-21: 51.4;HUVEC TERT2: 78.8;TIME: 110.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (2.78e-1)" "unprognostic (7.40e-2)" "unprognostic (3.08e-3)" "unprognostic (1.32e-2)" "unprognostic (3.39e-2)" "unprognostic (5.72e-2)" "unprognostic (2.16e-3)" "unprognostic (7.03e-2)" "unprognostic (2.22e-2)" "unprognostic (3.53e-2)" "unprognostic (1.13e-1)" "unprognostic (6.34e-2)" "unprognostic (2.71e-4)" "unprognostic (8.42e-3)" "unprognostic (6.21e-2)" "unprognostic (1.99e-1)" "unprognostic (8.74e-2)" 0.1 0.2 0.2 0.2 0.3 0.0 0.2 0.4 0.8 0.2 0.0 0.2 0.5 0.0 0.0 0.8 0.0 1.8 0.0 0.4 0.2 0.3 0.8 0.2 0.2 0.4 0.3 0.0 0.2 0.5 0.1 0.4 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.3 0.2 0.1 0.3 0.7 0.3 0.0 0.1 0.3 0.0 0.4 0.2 0.0 0.0 0.2 0.1 0.3 0.0 1.1 2.5 0.5 0.0 0.0 0.0 0.0 51.4 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 6.8 0.0 78.8 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 110.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.4 0.8 0.4 0.2 0.4 0.3 0.4 0.2 0.3 0.4 0.1 0.0 0.0 0.7 0.0 0.6 0.5 0.3 13.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.6 0.0 0.0 0.0 2.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.0 0.0 0.1 TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Uncertain "Plasma membrane" NA NA 180000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA037929: AB_10672613, HPA037930: AB_2675745" "unprognostic (7.31e-2)" "unprognostic (1.66e-2)" "unprognostic (5.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.13e-1)" "unprognostic (9.17e-2)" "unprognostic (2.47e-2)" "unprognostic (7.90e-2)" "unprognostic (4.27e-1)" "unprognostic (2.67e-2)" "unprognostic (4.22e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (2.46e-1)" "unprognostic (2.31e-2)" "unprognostic (2.41e-1)" "unprognostic (3.07e-1)" 62.7 27.3 11.8 17.3 10.2 3.3 41.9 4.6 9.4 43.3 18.0 23.6 28.8 40.3 30.3 55.4 35.3 28.1 23.3 11.3 9.2 14.7 31.6 40.3 6.6 9.6 8.8 32.2 30.9 18.9 17.1 29.5 7.2 33.6 16.2 3.3 44.2 40.2 67.2 83.0 26.6 29.4 4.9 18.1 52.8 10.1 11.0 22.3 25.0 29.9 14.3 38.5 45.6 6.7 89.5 58.7 41.2 33.6 127.8 97.1 31.0 61.5 113.8 46.3 42.5 26.1 59.5 2.0 38.5 101.2 49.6 151.7 31.4 105.3 30.1 34.2 10.4 11.5 38.2 12.2 86.6 14.4 4.3 96.8 123.5 70.9 54.6 57.5 60.0 12.4 13.2 9.3 65.3 45.4 11.0 14.7 45.8 46.5 45.9 16.9 57.2 25.9 53.5 116.6 14.6 22.6 81.5 121.5 44.3 29.0 182.2 11.9 115.1 47.3 45.8 56.6 35.2 15.0 4.1 11.3 107.0 4.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.8 10.2 4.6 9.4 11.3 9.2 9.6 8.8 7.2 4.9 11.0 6.7 38.1 12.8 35.4 12.7 1.9 83.6 28.0 61.9 40.9 4.8 24.8 23.9 7.9 38.6 39.0 44.1 2.1 16.8 1.3 27.3 0.0 31.8 1.8 18.5 25.4 25.9 18.0 7.4 7.2 22.3 3.2 31.2 49.5 38.4 2.5 3.7 19.6 46.0 3.9 8.4 4.8 25.8 18.3 1.5 25.4 2.9 48.1 3.8 17.8 1.9 0.7 4.0 0.0 4.5 2.4 38.8 14.3 49.2 0.6 41.2 18.2 2.4 15.4 1.3 32.9 41.2 26.9 1.5 3.0 68.9 88.2 24.5 2.3 23.4 14.5 36.8 TNS4 CTEN ENSG00000131746 "Tensin 4" Q8IZW8 17 40475828-40501623 "Predicted intracellular proteins" Apoptosis Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 205.0;vagina: 74.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 133.4;Basal prostatic cells: 117.7;Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 77.4;Suprabasal keratinocytes: 65.5;Urothelial cells: 50.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 77.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 136.2;HBEC3-KT: 613.4;hTCEpi: 435.3;hTERT-HME1: 138.8;OE19: 125.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (4.16e-2)" "unprognostic (9.83e-2)" "unprognostic (1.01e-1)" "unprognostic (3.40e-2)" "unprognostic (3.68e-4)" "unprognostic (7.88e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.89e-1)" "unprognostic (8.02e-3)" "unprognostic (2.01e-3)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (3.72e-1)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (7.08e-2)" 0.9 0.1 0.0 1.1 0.0 0.1 16.5 0.0 0.0 28.6 0.1 3.2 0.8 0.7 3.5 46.1 0.9 0.3 0.1 0.0 0.0 1.0 0.1 0.5 0.2 0.0 0.0 0.1 0.1 0.0 0.9 9.7 0.0 35.6 5.9 0.0 58.8 19.6 0.2 205.0 0.8 0.1 0.0 0.0 1.8 0.0 0.0 1.4 14.3 0.0 6.9 14.8 74.7 0.2 7.7 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 18.6 0.1 3.9 0.0 0.0 136.2 0.0 613.4 0.0 0.0 0.0 0.0 57.5 9.3 0.0 0.0 0.4 0.0 435.3 0.0 138.8 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.2 0.2 0.0 125.9 70.2 0.0 0.0 0.0 0.0 32.3 0.0 0.0 79.4 14.4 0.0 0.7 16.0 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.0 0.0 133.4 117.7 39.8 287.4 0.0 1.6 25.5 0.9 0.0 18.2 0.0 0.0 4.7 0.5 7.5 1.9 0.2 0.0 4.6 0.7 1.3 0.0 0.0 0.1 0.2 0.5 1.0 2.0 3.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 3.5 2.0 0.0 8.8 0.0 0.0 1.1 5.4 0.0 0.6 0.0 0.0 0.0 0.1 25.2 0.3 0.0 0.0 18.9 0.1 0.0 7.3 0.0 0.0 0.1 1.6 0.0 0.0 77.4 65.5 4.4 2.1 0.0 2.6 50.2 TP53AIP1 p53AIP1 ENSG00000120471 "Tumor protein p53 regulated apoptosis inducing protein 1" Q9HCN2 11 128934731-128943399 "Predicted intracellular proteins" Apoptosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;lymphoid tissue: 29.5;skin 1: 20.4;vagina: 13.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 45.5;Basal respiratory cells: 42.4;Basal squamous epithelial cells: 179.2;Endometrial ciliated cells: 38.7;Respiratory ciliated cells: 27.3;Squamous epithelial cells: 72.1;Suprabasal keratinocytes: 32.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044300, HPA048797" Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA044300: AB_2678888, HPA048797: AB_2680524" "unprognostic (4.12e-7)" "unprognostic (3.00e-2)" "unprognostic (1.48e-1)" "unprognostic (1.64e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-2)" "unprognostic (1.18e-1)" "unprognostic (4.66e-2)" "unprognostic (1.22e-1)" "unprognostic (6.62e-2)" "unprognostic (1.03e-1)" "unprognostic (2.94e-1)" "unprognostic (6.57e-6)" "unprognostic (1.10e-2)" "unprognostic (3.71e-1)" "unprognostic (7.75e-2)" "unprognostic (1.78e-2)" 0.0 0.6 0.9 0.0 0.8 0.0 1.3 1.1 1.3 5.6 0.6 0.1 0.0 0.1 2.5 24.5 2.7 0.0 0.0 0.8 0.6 0.8 0.1 0.2 0.0 1.0 1.0 0.0 0.2 0.0 1.8 0.0 0.9 2.0 0.0 0.5 3.9 0.8 0.1 20.4 0.1 0.0 0.5 0.0 0.0 1.6 1.0 29.5 0.0 0.0 1.1 0.0 13.6 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.8 1.1 1.3 0.8 0.6 1.0 1.0 0.9 0.5 1.0 0.8 0.2 0.0 0.5 1.0 0.0 45.5 11.4 42.4 179.2 0.7 1.5 23.9 0.3 0.0 5.3 0.0 0.0 0.1 0.0 0.3 7.9 0.0 0.9 38.7 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 1.8 1.1 0.0 0.4 1.8 1.0 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.2 27.3 0.4 0.0 0.6 1.6 0.2 0.3 72.1 32.7 0.3 0.3 0.0 0.3 2.6 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TRIM16 EBBP ENSG00000221926 "Tripartite motif containing 16" O95361 17 15627960-15684311 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 145.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 153.4;Squamous epithelial cells: 95.5;Urothelial cells: 111.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "T-reg: 45.1" "Lineage enriched" "Detected in many" 12 "T-cells: 45.1" "Cell line enhanced" "Detected in all" "A549: 283.8;HaCaT: 229.0;HeLa: 203.8;OE19: 364.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023623, HPA066431" Uncertain Supported "Plasma membrane,Cytosol" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (9.61e-2)" "unprognostic (1.31e-2)" "unprognostic (6.19e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.94e-3)" "unprognostic (3.75e-2)" "unprognostic (4.65e-1)" "unprognostic (3.31e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.08e-1)" "unprognostic (8.48e-2)" "unprognostic (9.21e-3)" "prognostic unfavorable (6.71e-4)" 18.3 32.7 14.1 7.8 16.2 17.4 13.4 17.7 21.5 44.9 10.3 14.1 22.8 6.1 4.9 145.9 8.8 16.3 23.1 13.5 15.8 8.5 5.9 14.5 9.7 16.9 16.0 7.3 6.0 3.6 4.4 34.5 17.2 10.2 11.2 3.6 38.0 11.7 28.1 44.9 12.5 9.0 15.8 6.0 31.7 12.7 17.2 10.1 18.7 27.2 37.3 35.7 70.2 22.1 91.5 283.8 8.6 19.4 40.4 46.1 9.6 14.8 51.9 17.9 25.0 17.2 115.6 9.8 54.7 64.7 106.9 229.0 25.6 65.7 12.0 120.0 16.4 4.5 203.8 9.5 67.1 5.4 9.6 25.7 40.9 39.3 22.3 49.6 38.8 11.4 5.7 45.8 49.2 32.2 20.2 11.7 13.1 364.2 17.0 8.7 71.8 6.9 92.4 116.0 6.4 17.7 64.7 72.2 22.1 49.7 10.9 12.6 61.0 22.5 26.3 10.9 51.3 11.1 12.9 1.0 34.6 12.6 58.3 0.4 3.8 1.0 1.2 1.1 0.8 0.5 4.9 1.5 2.6 0.6 1.3 2.6 0.6 0.9 0.5 0.4 45.1 2.3 14.1 16.2 17.7 21.5 13.5 15.8 16.9 16.0 17.2 15.8 17.2 22.1 34.9 38.5 2.6 14.0 5.3 30.8 59.0 55.6 10.2 7.2 11.8 5.7 12.5 10.0 73.5 11.0 18.8 13.6 2.8 9.9 0.0 49.1 1.1 16.5 9.9 28.7 4.2 9.0 9.6 17.3 8.4 9.6 34.7 25.7 4.5 12.4 3.6 3.2 4.0 3.3 14.0 21.7 28.5 2.9 8.6 3.9 7.2 2.9 7.2 11.2 13.0 6.6 4.1 18.6 19.2 153.4 26.9 4.5 3.7 29.5 4.3 6.2 33.5 8.4 6.6 5.8 14.0 10.3 12.1 95.5 77.6 4.7 5.9 60.9 18.4 111.9 TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 600.1;skin 1: 551.2;vagina: 269.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.0;Basal squamous epithelial cells: 250.4;Late spermatids: 150.3;Squamous epithelial cells: 552.9;Suprabasal keratinocytes: 460.6;Urothelial cells: 159.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 399.9;HBEC3-KT: 107.5;hTCEpi: 476.0;RT4: 190.5;SiHa: 268.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 4.0" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" 2.5 1.0 0.1 0.4 0.2 0.4 41.7 0.0 0.4 133.8 1.6 3.0 1.7 2.6 4.8 600.1 17.4 3.5 0.4 0.3 0.0 1.7 1.8 3.7 0.0 1.8 0.6 0.4 1.0 0.0 8.1 30.7 1.8 31.4 2.6 0.3 131.5 23.7 2.2 551.2 1.0 1.5 2.6 0.3 1.4 2.7 0.0 19.9 0.4 0.2 107.2 55.8 269.1 0.6 34.4 2.5 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.2 0.1 0.8 25.6 0.2 3.9 0.2 0.5 399.9 0.0 107.5 0.0 0.1 0.0 0.2 25.4 0.4 0.0 0.2 0.5 0.0 476.0 0.0 2.6 0.0 0.0 0.0 0.2 0.7 0.0 4.4 0.0 0.0 0.1 11.4 0.1 0.0 0.3 0.0 0.3 190.5 1.3 5.9 268.3 35.2 0.1 0.2 1.9 0.0 0.4 0.1 2.1 0.2 0.1 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.3 0.0 1.8 0.6 1.8 2.6 0.0 0.6 0.5 0.0 1.5 3.3 0.2 272.0 106.1 76.4 250.4 0.0 9.5 58.8 1.2 1.5 39.2 0.0 0.0 41.0 0.2 11.3 0.0 5.0 28.1 8.7 0.8 3.4 2.4 0.0 0.5 4.3 7.1 5.6 1.1 3.6 1.3 0.0 0.0 0.4 5.0 0.0 0.1 2.1 12.2 0.0 30.3 150.3 0.6 1.4 23.2 1.0 0.0 0.0 0.0 0.0 0.1 57.1 11.3 0.0 0.0 66.0 0.2 0.6 64.6 0.0 0.0 0.1 4.9 0.8 2.6 552.9 460.6 24.8 2.4 0.1 3.7 159.3 TTLL12 KIAA0153 ENSG00000100304 "Tubulin tyrosine ligase like 12" Q14166 22 43166622-43187134 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 104.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 56.3;Paneth cells: 56.9;Squamous epithelial cells: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003054, CAB046029" Approved Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB046029: AB_11128395, HPA003054: AB_2666770" "unprognostic (2.45e-2)" "unprognostic (3.47e-2)" "unprognostic (7.37e-3)" "unprognostic (5.40e-2)" "unprognostic (2.65e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (5.81e-3)" "unprognostic (2.24e-1)" "unprognostic (6.08e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-3)" "unprognostic (1.40e-1)" "unprognostic (6.66e-2)" "unprognostic (2.81e-2)" 13.9 28.1 8.7 16.6 8.5 26.2 13.0 10.0 15.1 25.8 1.8 35.6 24.4 13.9 3.6 104.5 13.9 18.5 10.2 9.5 9.7 9.0 21.0 9.3 11.2 16.2 8.7 23.7 19.2 9.4 14.7 7.2 15.8 15.2 19.5 4.7 21.9 6.8 12.6 36.8 22.9 7.1 6.5 10.7 33.4 25.7 8.1 8.0 9.1 7.9 12.9 15.5 37.0 9.1 113.2 46.7 18.5 45.9 27.8 19.0 59.7 36.3 12.8 34.1 17.8 76.2 62.7 107.9 43.0 30.3 16.7 78.8 77.3 66.5 8.7 13.6 123.3 26.5 73.6 66.4 43.5 120.2 26.4 30.2 79.3 40.8 43.4 18.3 36.5 52.1 166.1 24.8 16.1 104.4 84.1 65.2 67.4 78.9 46.1 84.4 63.5 155.6 28.7 36.6 56.2 23.2 77.1 111.2 41.6 8.4 44.0 52.9 35.2 22.7 31.7 44.1 51.4 41.6 55.4 81.0 25.7 60.8 31.4 0.0 2.3 0.3 2.6 1.2 2.5 1.8 2.5 1.9 1.8 1.1 2.4 1.7 0.6 2.3 1.7 1.6 1.8 1.9 8.7 8.5 10.0 15.1 9.5 9.7 16.2 8.7 15.8 6.5 8.1 9.1 3.7 6.4 6.7 3.6 6.4 11.2 11.4 11.0 17.1 8.5 13.5 9.9 4.5 17.2 7.6 7.3 4.2 8.8 3.2 56.3 5.9 14.2 1.0 5.0 9.5 5.8 9.1 39.1 8.0 8.6 19.0 6.0 34.1 14.7 0.0 14.3 8.2 35.0 9.8 0.0 8.5 30.6 10.2 14.2 2.9 2.6 8.7 7.5 10.6 1.9 7.7 4.2 4.1 3.0 2.2 25.8 56.9 17.0 9.4 28.7 32.1 8.3 5.0 5.6 0.0 5.2 7.2 2.0 12.2 60.2 18.2 4.1 5.9 13.4 39.9 13.7 TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 364.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 516.5;Suprabasal keratinocytes: 368.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cell line enhanced" "Detected in all" "AF22: 241.1;CACO-2: 247.6;SuSa: 365.5;WM-115: 280.1" "Low region specificity" "Detected in all" "CAB015339, HPA043640, HPA046280" Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB015339: AB_2210539, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.57e-1)" "unprognostic (9.86e-3)" "unprognostic (5.90e-3)" "unprognostic (7.98e-3)" "unprognostic (4.02e-3)" "unprognostic (1.67e-1)" "unprognostic (1.82e-3)" "unprognostic (7.53e-2)" "unprognostic (1.48e-3)" "unprognostic (9.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.42e-2)" "prognostic favorable (4.65e-4)" "unprognostic (2.39e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (1.61e-4)" 58.8 17.8 266.1 19.3 251.1 67.5 47.8 130.1 287.5 32.7 10.0 78.0 24.2 50.8 28.0 90.6 23.5 21.5 29.4 248.3 364.3 31.1 67.0 16.4 11.0 292.6 212.2 15.5 39.4 2.2 56.3 23.9 334.3 17.5 8.2 49.9 52.2 15.6 22.3 151.4 34.9 41.7 131.6 7.7 41.0 9.5 204.4 6.4 10.0 11.8 9.6 23.6 51.2 169.4 55.9 45.3 241.1 53.6 30.6 34.0 14.5 119.8 44.7 80.6 115.7 247.6 18.4 27.4 72.9 115.5 80.2 26.0 86.6 26.8 28.0 134.1 57.7 9.4 11.4 77.0 31.6 1.5 8.4 35.1 31.1 85.1 5.3 28.9 37.3 10.6 33.7 8.8 74.2 25.1 14.9 2.8 207.2 16.0 58.3 12.4 22.6 18.9 28.0 27.4 57.6 52.9 30.5 8.5 179.7 365.5 19.1 2.0 76.0 53.9 56.7 117.3 65.8 3.2 4.6 18.8 19.7 7.0 280.1 0.0 1.1 0.0 2.2 1.6 2.4 3.2 2.1 3.1 0.5 0.6 1.0 2.0 0.3 0.4 1.3 0.2 3.2 1.2 266.1 251.1 130.1 287.5 248.3 364.3 292.6 212.2 334.3 131.6 204.4 169.4 125.3 16.0 13.1 43.1 31.6 311.4 63.3 87.0 132.6 105.6 32.0 134.6 20.4 42.9 62.7 12.9 16.7 6.0 53.4 87.0 217.2 54.0 60.9 46.7 29.6 40.6 73.1 322.3 59.9 182.4 50.4 96.2 185.0 57.9 34.9 10.1 12.5 55.6 50.8 516.5 73.0 103.9 73.2 6.3 164.4 32.9 20.8 36.7 129.9 24.4 72.7 261.0 0.0 18.1 23.0 103.4 181.8 15.4 15.8 34.9 126.3 40.4 50.3 86.2 6.6 95.6 87.9 32.4 14.9 140.6 368.5 6.2 58.9 6.4 60.0 54.7 UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "esophagus: 83.8" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 40.7" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "SiHa: 112.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" 0.1 1.3 0.2 0.0 0.2 0.0 0.4 0.5 0.8 1.2 0.4 0.3 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.3 0.2 0.7 4.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 5.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 5.2 0.4 7.1 1.0 0.0 1.8 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 112.2 7.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.8 0.3 0.2 0.2 0.5 0.2 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 1.3 4.6 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 40.7 1.7 0.0 0.0 0.0 0.5 8.5 VSIG10L ENSG00000186806 "V-set and immunoglobulin domain containing 10 like" Q86VR7 19 51331536-51342124 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 20.3;esophagus: 62.3;salivary gland: 23.5;vagina: 22.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 10.1;Melanocytes: 5.4;Sertoli cells: 6.6;Squamous epithelial cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 4.7;OE19: 11.0;T-47d: 8.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA060453, HPA066745" Uncertain Approved Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA060453: AB_2684280, HPA066745: AB_2685712" "unprognostic (1.70e-2)" "unprognostic (1.95e-2)" "unprognostic (1.30e-2)" "unprognostic (2.98e-3)" "unprognostic (1.08e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.75e-4)" "unprognostic (2.40e-3)" "unprognostic (2.78e-1)" "unprognostic (9.87e-2)" "unprognostic (2.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.90e-4)" "unprognostic (1.42e-2)" "unprognostic (8.51e-2)" "unprognostic (7.74e-2)" "unprognostic (5.19e-3)" 0.2 0.1 0.1 0.0 0.4 0.1 0.8 0.8 0.5 20.3 0.0 0.1 0.0 0.0 0.0 62.3 0.1 0.3 0.1 0.1 0.7 0.1 0.7 0.1 0.1 0.5 1.0 0.2 0.0 0.0 0.1 0.0 0.8 1.2 0.0 0.0 23.5 0.1 0.1 10.6 0.2 0.0 0.1 0.1 0.1 0.3 0.6 0.1 0.1 0.0 6.3 0.2 22.3 0.7 0.0 0.9 0.0 0.3 0.4 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.7 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.1 0.2 4.7 0.0 0.0 0.8 0.0 0.5 0.1 0.0 0.0 0.0 0.2 0.4 1.3 0.0 0.4 0.0 0.1 0.6 11.0 0.4 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 8.4 0.0 0.0 0.0 0.1 0.7 0.0 1.1 0.7 0.1 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.8 0.5 0.1 0.7 0.5 1.0 0.8 0.1 0.6 0.7 1.2 0.0 0.5 1.3 0.8 0.6 1.1 0.6 1.8 1.6 2.2 1.8 0.9 0.0 0.1 0.0 0.0 0.4 0.2 0.9 0.0 1.1 0.2 0.0 0.3 0.5 1.2 0.0 0.6 0.0 0.9 1.6 1.1 0.2 1.3 1.0 1.4 1.2 4.5 10.1 1.0 0.5 0.0 3.2 0.9 0.7 2.1 2.4 5.4 1.0 1.1 1.4 0.0 0.0 0.9 0.4 1.3 4.1 0.1 1.0 1.6 0.9 0.0 0.6 6.6 1.5 1.2 0.5 2.6 6.1 0.4 0.5 0.4 2.2 0.7 0.7 ZBTB5 KIAA0354 ENSG00000168795 "Zinc finger and BTB domain containing 5" O15062 9 37438102-37465450 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021521 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA021521: AB_2670736" "unprognostic (2.36e-2)" "unprognostic (2.78e-2)" "unprognostic (5.22e-2)" "unprognostic (6.35e-2)" "unprognostic (1.55e-2)" "unprognostic (2.08e-2)" "unprognostic (4.96e-3)" "unprognostic (5.81e-2)" "unprognostic (3.95e-2)" "unprognostic (1.43e-1)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" "unprognostic (1.27e-3)" "unprognostic (5.73e-3)" "unprognostic (2.30e-1)" "unprognostic (2.77e-3)" "unprognostic (1.80e-1)" 4.9 6.2 4.9 5.6 5.8 13.6 7.4 5.9 5.0 6.3 5.0 6.1 6.3 6.3 7.7 17.8 5.9 5.4 5.5 4.7 5.0 7.4 12.9 7.9 9.0 5.7 5.3 8.4 8.4 7.6 4.7 6.2 5.5 7.2 5.8 9.2 7.8 6.7 5.2 11.9 7.2 5.3 5.0 7.2 7.2 8.8 5.2 9.5 10.3 7.2 12.1 5.6 9.3 7.8 9.3 10.5 26.6 16.6 6.7 4.7 11.4 7.5 5.8 9.0 7.4 7.8 6.7 18.8 7.9 5.6 6.6 11.1 17.5 6.2 6.9 13.9 9.1 6.9 28.7 9.1 6.5 8.6 5.8 4.5 15.5 4.5 9.5 10.2 10.2 14.8 16.6 15.6 6.8 5.9 18.2 6.3 6.8 10.0 5.3 16.3 12.8 7.2 8.7 8.2 12.2 21.9 7.3 11.7 5.8 13.3 18.7 8.3 7.0 6.3 17.3 3.7 7.2 8.3 9.8 16.3 5.8 7.3 6.8 0.1 0.4 0.0 0.6 0.2 0.7 0.9 0.5 0.5 0.8 0.7 0.8 0.9 0.0 0.3 0.0 0.2 0.5 0.3 4.9 5.8 5.9 5.0 4.7 5.0 5.7 5.3 5.5 5.0 5.2 7.8 4.0 16.0 6.5 12.7 5.1 14.3 8.8 5.0 11.4 2.0 8.4 6.6 3.2 7.2 9.3 1.8 6.2 3.9 3.7 6.5 0.0 4.0 2.2 7.3 4.2 5.6 8.4 2.1 8.9 3.2 2.2 4.2 5.1 7.3 1.3 6.6 3.6 8.6 2.4 13.5 9.1 5.2 4.1 1.9 4.8 5.3 4.1 3.4 3.6 10.3 3.7 3.3 1.0 13.6 15.5 4.1 3.7 3.8 4.2 12.6 3.1 3.5 6.0 5.1 0.0 5.4 4.0 7.5 7.9 17.9 18.2 5.7 2.7 4.4 5.1 8.2 ZBTB7C "ZBTB36, ZNF857C" ENSG00000184828 "Zinc finger and BTB domain containing 7C" A1YPR0 18 48026672-48410752 "Predicted intracellular proteins, Transcription factors" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8" "Cell type enhanced" "Detected in many" "Astrocytes: 47.0;Basal squamous epithelial cells: 45.5;Distal enterocytes: 52.5;Excitatory neurons: 48.8;Gastric mucus-secreting cells: 49.5;Oligodendrocyte precursor cells: 51.3;Squamous epithelial cells: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 4 "RT4: 42.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "prognostic favorable (1.59e-4)" "unprognostic (2.83e-3)" "unprognostic (6.60e-2)" "unprognostic (2.91e-3)" "unprognostic (8.57e-2)" "unprognostic (2.63e-2)" "unprognostic (1.58e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" "unprognostic (2.71e-1)" "unprognostic (5.52e-3)" "unprognostic (3.85e-3)" "unprognostic (2.89e-2)" 5.3 11.2 7.8 2.0 3.9 0.4 6.1 3.6 5.4 8.4 0.0 14.5 1.8 1.7 17.2 40.8 14.0 3.4 1.6 4.6 8.1 1.9 0.9 4.5 0.6 7.6 6.6 6.5 1.0 5.2 1.8 3.7 4.3 3.2 13.4 6.3 14.7 3.9 1.7 22.4 2.9 2.1 5.0 9.2 13.8 9.2 14.7 0.3 16.7 1.6 3.8 11.0 19.5 4.8 0.0 0.0 1.5 1.2 0.2 0.4 0.8 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.5 0.0 1.7 2.7 0.1 0.4 0.2 0.3 1.3 0.2 3.2 0.1 0.0 0.0 0.4 0.1 0.7 0.2 0.4 0.0 0.0 1.2 0.0 0.1 0.6 0.7 1.7 0.5 0.5 8.6 0.0 0.1 0.0 9.7 1.3 42.7 5.4 6.9 0.6 0.3 0.0 1.4 0.9 0.0 0.0 0.1 0.6 0.5 0.0 0.1 0.2 0.0 2.7 0.1 0.2 1.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.2 0.0 0.0 7.8 3.9 3.6 5.4 4.6 8.1 7.6 6.6 4.3 5.0 14.7 4.8 0.5 6.4 1.5 47.0 0.1 6.1 5.3 11.6 45.5 1.2 6.0 8.4 3.1 12.8 9.5 1.8 0.0 13.7 0.1 52.5 0.0 1.0 9.6 4.8 1.8 2.9 4.8 0.0 48.8 4.0 0.8 3.4 49.5 6.7 0.0 1.0 0.0 0.6 1.5 1.7 7.0 30.8 6.1 2.1 0.8 4.4 3.7 0.4 3.6 22.5 0.1 1.0 0.0 51.3 2.1 1.2 14.6 12.0 0.0 7.5 3.5 0.0 7.6 2.5 13.1 8.8 11.9 0.9 0.9 96.9 8.8 12.6 0.2 6.6 18.3 13.7 ZFP36L1 "Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B" ENSG00000185650 "ZFP36 ring finger protein like 1" Q07352 14 68787660-68796253 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA transport, Transport" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1973.2;Squamous epithelial cells: 2019.8;Suprabasal keratinocytes: 3223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 2901.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 2901.2" "Cell line enhanced" "Detected in all" "hTERT-HME1: 462.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001301 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA001301: AB_1080644" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (3.81e-3)" "unprognostic (1.13e-3)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (6.45e-3)" "unprognostic (5.77e-2)" "unprognostic (2.97e-1)" "unprognostic (5.68e-2)" 342.7 107.9 108.1 218.2 108.3 84.0 305.6 118.0 96.1 466.4 91.7 335.1 127.5 423.1 107.7 293.0 303.3 174.9 178.8 98.7 184.1 157.8 260.1 242.7 199.5 207.8 187.5 453.5 225.4 161.7 67.3 315.8 145.0 222.3 104.2 57.5 319.3 201.7 93.1 511.3 151.5 316.0 162.7 178.5 196.9 49.3 142.6 130.1 190.6 89.6 150.4 335.8 467.0 166.8 235.6 211.8 94.7 139.0 234.4 187.2 203.9 96.4 169.6 59.1 72.9 93.9 159.5 58.4 59.5 177.4 85.5 108.4 8.8 313.8 70.0 27.9 13.2 21.5 115.0 68.2 133.8 3.3 24.3 157.6 396.4 69.1 462.1 195.2 119.2 17.1 61.5 113.7 314.4 54.1 9.3 11.1 78.7 105.1 31.7 150.5 127.1 17.8 213.4 155.3 1.0 2.5 113.7 163.4 87.8 131.9 148.3 3.0 254.4 167.3 122.8 139.0 101.0 62.9 32.9 39.9 213.5 1.4 66.9 230.8 240.9 3.9 211.1 244.7 197.2 266.0 168.8 150.3 123.8 461.4 179.3 162.2 2901.2 154.3 176.1 16.2 174.5 257.5 108.1 108.3 118.0 96.1 98.7 184.1 207.8 187.5 145.0 162.7 142.6 166.8 830.2 477.5 415.6 172.7 513.8 1333.5 761.2 830.2 1973.2 4.6 750.7 504.4 84.2 420.4 523.9 364.1 0.0 442.1 276.5 164.4 84.1 575.8 97.0 434.6 479.6 571.0 20.4 87.7 1.5 573.1 476.6 894.3 218.6 656.2 200.8 21.1 292.7 595.6 548.3 0.0 0.7 225.3 215.7 613.9 1272.8 72.2 502.0 670.0 528.3 142.4 499.0 211.9 131.8 63.8 0.9 544.8 138.3 397.2 191.7 657.7 138.4 143.7 314.5 9.2 269.5 562.0 714.4 12.2 13.3 2019.8 3223.6 898.7 405.2 157.1 191.1 817.8 ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 32.2;Pancreatic endocrine cells: 72.0;Squamous epithelial cells: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Cell line enhanced" "Detected in many" "A-431: 124.4;EFO-21: 139.9;HBEC3-KT: 100.0;PC-3: 87.7;TIME: 236.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" 5.2 11.6 4.0 5.6 4.2 8.7 12.2 4.8 3.7 69.5 10.9 4.5 1.8 21.8 328.7 326.7 16.4 6.7 1.8 3.2 3.9 11.0 2.1 12.1 4.5 3.5 3.8 6.1 4.3 3.7 8.4 24.9 3.5 24.5 4.2 3.4 44.8 144.1 2.9 53.7 2.6 10.3 4.2 4.5 7.4 3.4 4.3 3.6 21.3 2.9 41.0 11.6 117.5 3.9 124.4 25.9 2.4 1.6 3.0 4.0 5.5 6.0 0.4 14.8 2.2 0.9 36.7 1.6 139.9 9.0 1.4 17.3 3.7 100.0 60.1 1.5 2.4 7.9 9.8 4.1 7.0 0.5 0.6 2.9 70.2 1.6 57.0 14.6 76.5 1.6 0.5 1.1 0.4 29.1 0.5 0.7 1.9 31.4 87.7 0.5 0.4 0.9 7.7 11.5 1.0 8.2 0.2 22.7 3.6 23.3 23.3 2.7 236.2 0.8 50.5 3.0 4.5 1.2 1.0 1.1 1.6 8.9 1.7 51.8 27.4 11.4 1.0 24.4 0.6 0.7 0.7 1.2 7.4 0.6 1.1 0.7 18.5 0.5 21.1 4.9 1.0 20.7 4.0 4.2 4.8 3.7 3.2 3.9 3.5 3.8 3.5 4.2 4.3 3.9 1.1 12.8 2.6 1.3 0.7 9.2 6.2 5.7 4.6 0.5 5.7 7.6 0.9 1.5 9.4 9.2 2.1 3.8 1.7 1.0 0.0 8.6 0.6 14.1 4.2 1.1 0.0 0.0 1.0 3.0 5.0 2.2 2.6 32.2 1.3 3.9 1.4 0.1 9.4 0.0 1.7 2.5 2.0 11.3 4.0 0.3 1.2 9.5 3.6 0.0 14.4 4.0 0.0 1.0 1.4 72.0 0.3 1.2 0.1 7.6 0.3 1.2 6.9 0.3 0.0 0.5 1.9 4.2 5.8 69.7 21.2 0.7 0.8 0.4 2.4 21.3 ZNF436 "KIAA1710, Zfp46" ENSG00000125945 "Zinc finger protein 436" Q9C0F3 1 23359448-23369836 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 22.2;Squamous epithelial cells: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 18.8;HSkMC: 34.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043817 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA043817: AB_10794774" "unprognostic (1.50e-1)" "unprognostic (2.91e-1)" "unprognostic (1.44e-1)" "unprognostic (1.93e-1)" "unprognostic (8.10e-2)" "unprognostic (2.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.86e-1)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.92e-1)" "unprognostic (9.51e-3)" "unprognostic (5.04e-2)" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (7.75e-3)" 10.0 14.8 4.8 2.3 5.2 1.4 9.8 5.5 5.4 9.8 4.5 8.5 3.1 9.9 8.0 16.5 6.9 5.5 8.3 5.5 5.3 4.0 3.7 4.2 2.7 6.3 5.2 15.4 6.9 5.3 4.4 4.2 5.6 9.5 3.1 4.6 14.6 5.1 6.5 12.6 5.6 6.2 5.6 7.0 6.1 7.9 5.4 3.5 9.0 6.2 3.6 10.4 10.2 5.9 3.8 2.4 8.6 4.5 9.1 18.8 4.1 3.4 4.6 4.3 5.0 1.4 3.3 2.6 3.8 4.9 2.8 4.8 15.0 5.7 4.6 3.2 3.3 2.8 5.3 2.2 3.6 1.2 1.9 34.9 8.0 3.6 4.1 7.8 6.2 3.1 3.4 1.8 4.5 1.8 2.9 2.1 0.3 1.7 3.8 3.8 3.6 2.5 3.4 9.5 3.9 4.9 9.6 4.7 3.7 2.9 2.6 1.4 5.0 3.7 2.7 2.9 1.9 2.8 3.6 2.1 2.9 2.3 2.9 0.0 0.7 0.7 0.7 0.8 0.7 0.4 0.5 0.8 1.1 0.5 0.8 0.7 0.5 2.6 0.8 0.1 0.9 0.6 4.8 5.2 5.5 5.4 5.5 5.3 6.3 5.2 5.6 5.6 5.4 5.9 7.8 0.0 0.5 2.6 2.0 5.2 1.6 1.9 22.2 4.1 6.9 5.0 6.4 1.5 1.6 5.5 6.2 3.8 2.6 3.5 0.0 2.9 2.3 5.0 8.5 14.0 3.6 1.7 4.2 4.9 1.8 9.6 2.0 7.8 0.0 9.4 3.3 3.1 2.1 10.1 3.3 4.6 2.0 1.9 3.8 1.5 9.9 2.1 5.4 0.0 4.5 9.3 2.1 2.5 3.1 3.6 5.9 11.7 2.1 3.3 4.0 2.8 2.4 2.4 0.0 4.5 4.5 5.5 6.9 22.1 9.7 2.9 2.4 7.9 3.1 2.0 ZNF503 "FLJ45745, MGC2555, Nlz2" ENSG00000165655 "Zinc finger protein 503" Q96F45 10 75397830-75401764 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 255.0;Squamous epithelial cells: 189.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 115.1;PC-3: 149.2;U-87 MG: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026848 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Nucleoplasm "HPA026848: AB_10610704" "unprognostic (1.18e-1)" "unprognostic (8.56e-2)" "unprognostic (8.63e-3)" "unprognostic (7.41e-2)" "unprognostic (2.82e-1)" "unprognostic (3.57e-2)" "unprognostic (9.63e-2)" "unprognostic (7.42e-2)" "unprognostic (3.42e-2)" "unprognostic (3.22e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.97e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" 14.5 39.9 6.1 3.1 10.1 2.0 9.2 3.8 5.2 34.5 1.0 17.7 8.1 44.1 10.3 20.1 23.8 2.4 9.0 7.4 5.5 25.6 7.1 14.2 1.5 12.0 9.2 46.3 25.4 4.6 4.8 3.3 7.6 17.5 1.8 1.4 9.5 17.6 3.6 5.3 8.5 7.7 10.0 8.0 16.3 2.4 8.1 1.1 7.8 2.1 1.0 13.8 18.2 6.5 5.2 4.9 1.1 6.3 10.6 7.1 1.6 4.6 2.8 1.9 1.7 7.5 20.4 0.0 13.4 4.6 1.1 9.4 0.7 4.9 1.4 0.0 115.1 0.0 12.4 24.8 8.5 6.1 12.9 19.1 4.8 3.5 2.0 16.6 0.5 0.5 0.1 0.2 2.6 2.7 0.2 18.8 0.1 3.8 149.2 0.0 5.6 0.1 2.8 4.1 4.1 5.2 8.5 0.6 27.1 1.0 1.0 4.2 3.9 14.6 16.3 30.7 13.0 0.0 0.0 0.0 44.9 27.2 11.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 10.1 3.8 5.2 7.4 5.5 12.0 9.2 7.6 10.0 8.1 6.5 27.2 38.5 11.6 2.3 1.7 27.1 35.6 15.0 255.0 23.7 7.7 42.3 20.4 10.0 10.1 40.5 20.9 0.5 2.1 0.8 58.7 45.9 0.1 53.2 72.2 41.0 3.6 5.3 12.6 34.7 0.3 60.1 18.3 48.1 6.3 2.7 44.6 10.3 13.5 6.7 3.2 6.7 10.2 27.4 30.5 2.0 59.7 30.7 24.9 13.1 8.2 7.7 0.0 4.0 0.7 33.2 1.5 49.2 3.9 19.7 13.4 32.5 1.7 26.3 39.5 10.2 78.1 0.2 6.0 189.3 13.9 0.3 4.0 24.5 9.7 14.3 ZNF561 MGC45408 ENSG00000171469 "Zinc finger protein 561" Q8N587 19 9604680-9621236 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA055332, HPA062397" Uncertain Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA055332: AB_2682786, HPA062397: AB_2684751" "unprognostic (6.68e-2)" "unprognostic (1.26e-1)" "unprognostic (6.86e-3)" "unprognostic (3.43e-2)" "unprognostic (1.18e-2)" "unprognostic (3.63e-3)" "unprognostic (9.92e-2)" "unprognostic (2.53e-2)" "unprognostic (9.54e-2)" "prognostic favorable (1.31e-4)" "unprognostic (9.21e-2)" "unprognostic (3.34e-2)" "prognostic favorable (1.16e-4)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (3.27e-3)" "unprognostic (2.85e-3)" 8.9 8.8 4.6 8.4 5.5 10.2 17.2 7.2 7.6 13.5 5.3 10.3 8.0 17.9 12.0 16.3 18.5 12.9 9.8 5.7 5.6 12.5 11.2 11.2 10.8 6.2 5.8 20.1 10.4 13.6 7.6 10.5 6.2 17.4 12.8 7.3 9.7 17.6 9.1 14.3 8.5 26.0 4.9 9.7 10.6 6.3 5.8 14.5 15.4 14.6 12.5 18.6 12.1 6.1 14.4 5.7 31.8 24.3 26.2 30.9 28.0 18.9 25.2 23.2 26.1 10.7 6.1 13.2 13.5 19.1 13.3 8.2 21.6 36.1 24.2 18.5 23.3 16.9 12.2 18.9 15.7 20.9 16.0 20.5 55.4 17.4 22.4 36.3 29.7 9.6 19.3 17.4 29.0 6.9 9.4 23.3 25.6 12.3 18.1 11.1 15.8 13.5 20.3 51.7 19.7 19.6 0.4 10.9 14.7 30.1 14.6 14.6 9.3 24.8 8.8 17.2 17.9 20.2 30.2 17.7 12.2 5.6 16.8 4.0 5.1 5.8 4.9 5.1 6.2 2.8 3.9 4.4 4.1 3.9 5.4 4.0 3.4 1.7 2.7 3.6 4.0 3.4 4.6 5.5 7.2 7.6 5.7 5.6 6.2 5.8 6.2 4.9 5.8 6.1 8.2 0.0 7.0 5.9 7.9 13.8 25.2 31.9 16.5 9.4 11.5 16.5 9.8 11.5 17.9 14.7 6.2 8.0 11.0 7.3 3.9 11.1 6.9 11.1 12.1 8.9 11.4 11.6 10.0 6.5 8.5 7.7 12.2 9.0 7.6 25.5 10.8 8.2 10.9 10.1 10.5 7.7 16.2 12.8 5.8 9.7 11.5 8.3 3.6 6.5 12.2 6.3 17.5 17.6 12.0 8.6 6.8 13.2 6.2 10.9 9.8 8.5 30.3 11.9 6.6 9.1 10.4 8.2 10.6 23.6 22.4 6.4 10.2 16.2 7.7 25.9 ZNF749 FLJ16360 ENSG00000186230 "Zinc finger protein 749" O43361 19 57435325-57447101 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 27.9;Excitatory neurons: 24.2;Inhibitory neurons: 21.1;Melanocytes: 23.2;Oligodendrocyte precursor cells: 18.1;Squamous epithelial cells: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 24.0" "HPA042082, HPA042091, HPA056001" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear membrane" "HPA042082: AB_10796572, HPA042091: AB_10793874, HPA056001: AB_2683005" "unprognostic (2.54e-1)" "unprognostic (1.55e-1)" "unprognostic (6.67e-2)" "unprognostic (9.92e-2)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.87e-1)" "unprognostic (8.23e-2)" "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (9.27e-3)" "unprognostic (2.76e-2)" "unprognostic (3.05e-5)" "unprognostic (1.35e-1)" "unprognostic (4.19e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-1)" 1.3 1.2 1.6 1.8 1.4 1.4 1.7 3.6 1.5 1.1 1.0 1.0 1.5 1.3 0.9 1.4 1.6 0.9 1.0 1.6 1.2 1.1 1.6 1.0 1.8 0.8 1.1 1.7 1.1 1.5 1.1 1.3 1.1 1.2 0.9 4.0 1.5 0.9 1.3 2.2 1.2 1.1 0.3 1.6 1.2 1.3 1.2 1.9 1.3 0.4 1.6 1.3 1.3 1.7 2.8 6.2 5.5 5.9 1.3 1.3 2.3 1.6 1.1 2.6 4.6 2.5 2.0 5.4 1.5 1.6 1.9 2.1 4.9 4.2 3.8 2.3 24.0 4.6 6.5 3.0 1.9 5.6 3.0 1.9 4.6 3.1 7.7 2.5 1.3 5.6 4.7 6.4 2.0 1.3 6.6 2.4 5.6 1.8 8.8 6.9 7.8 4.2 1.4 6.5 5.7 4.7 3.2 2.0 1.5 4.2 2.9 1.8 1.5 5.0 3.7 1.7 4.8 5.0 6.8 5.8 2.8 2.4 3.2 0.2 0.4 0.1 0.6 0.9 0.9 0.9 1.1 0.8 1.1 0.8 1.2 0.8 0.2 0.6 0.4 0.5 0.8 0.8 1.6 1.4 3.6 1.5 1.6 1.2 0.8 1.1 1.1 0.3 1.2 1.7 1.1 3.2 1.1 7.2 6.7 2.4 1.3 2.9 27.9 1.2 4.0 2.9 0.5 7.2 3.2 0.0 0.0 0.9 2.3 0.4 3.9 1.1 1.0 7.1 1.4 2.3 3.0 8.8 24.2 0.4 0.6 2.5 10.7 3.5 0.0 1.2 1.1 4.0 0.8 3.3 21.1 1.7 2.0 0.8 1.6 0.1 0.6 1.9 23.2 5.6 0.7 0.2 0.0 18.1 10.6 0.8 0.3 0.0 11.6 0.9 3.8 8.1 3.4 0.8 6.6 1.8 2.0 1.2 1.8 35.9 3.1 0.8 4.3 0.3 1.1 1.1 ZNF750 "FLJ13841, Zfp750" ENSG00000141579 "Zinc finger protein 750" Q32MQ0 17 82829434-82840022 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 139.0;vagina: 51.7" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 33.3;Squamous epithelial cells: 156.8;Suprabasal keratinocytes: 41.1;Syncytiotrophoblasts: 68.1;Urothelial cells: 51.3" "Cancer enhanced" "Detected in many" "cervical cancer: 20.5;head and neck cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.3;hTCEpi: 7.2;MCF7: 5.4;SK-BR-3: 14.0" "Not detected" "Not detected" "HPA021573, HPA023012" Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA021573: AB_1859438, HPA023012: AB_1859439" "unprognostic (3.46e-3)" "unprognostic (1.94e-2)" "unprognostic (7.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (9.73e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-3)" "unprognostic (1.34e-1)" "unprognostic (4.33e-2)" "unprognostic (6.30e-3)" "unprognostic (1.23e-2)" "unprognostic (5.30e-3)" "unprognostic (3.04e-2)" "unprognostic (5.94e-2)" "unprognostic (2.04e-1)" "unprognostic (4.25e-2)" 0.5 0.1 0.8 0.0 1.2 0.1 5.1 0.5 0.9 25.0 0.0 0.1 0.1 0.2 4.1 96.1 0.6 0.2 0.6 0.6 0.2 0.4 0.1 2.0 0.0 1.0 0.3 0.1 0.2 2.2 2.9 3.9 1.0 3.3 0.0 0.0 33.6 2.7 12.0 139.0 0.1 0.0 0.2 0.1 0.2 0.4 0.6 5.1 3.5 0.0 14.7 4.9 51.7 2.3 0.1 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.3 1.2 1.0 0.0 14.0 0.0 1.7 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.5 0.9 0.6 0.2 1.0 0.3 1.0 0.2 0.6 2.3 0.6 0.0 8.2 0.0 0.0 5.2 14.3 19.6 9.1 0.0 7.4 5.0 0.4 0.0 21.2 0.0 0.0 23.1 0.0 0.0 0.0 0.0 2.4 27.1 3.3 0.9 0.0 0.0 0.4 0.0 1.9 0.3 0.0 33.3 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.0 10.2 0.0 0.3 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 7.6 0.0 0.1 14.2 0.0 0.0 0.1 1.5 0.0 0.2 156.8 41.1 68.1 0.2 0.0 0.0 51.3 ZNF77 pT1 ENSG00000175691 "Zinc finger protein 77" Q15935 19 2933218-2944971 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 14.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023397 Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli Nucleoplasm "HPA023397: AB_1859447" "unprognostic (1.17e-2)" "prognostic favorable (8.49e-4)" "unprognostic (2.18e-1)" "prognostic favorable (6.65e-5)" "unprognostic (2.01e-3)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "prognostic favorable (6.79e-6)" "unprognostic (2.06e-1)" "unprognostic (5.03e-2)" "unprognostic (3.93e-3)" "unprognostic (2.65e-3)" "unprognostic (3.20e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.84e-2)" "unprognostic (1.79e-3)" 2.7 2.7 2.3 1.2 2.3 2.2 4.6 4.6 2.6 3.5 2.0 2.5 1.4 3.0 2.8 3.1 2.9 1.4 2.6 2.1 2.2 3.4 2.7 2.8 2.5 2.2 2.2 3.4 3.0 3.3 3.1 2.9 2.3 2.8 2.1 4.0 2.6 2.1 2.6 3.2 2.1 2.9 2.1 2.6 3.2 3.6 2.2 3.4 3.0 4.1 3.4 2.6 2.9 2.7 4.3 2.1 9.4 5.5 1.9 2.5 4.2 2.5 3.8 5.0 5.9 6.5 1.7 4.8 2.1 2.8 2.7 3.4 6.1 4.1 8.3 0.7 4.7 5.9 3.4 7.3 4.8 0.2 4.6 3.9 5.6 3.9 5.7 6.2 7.0 9.2 7.7 0.0 3.4 4.7 7.2 4.2 2.1 3.7 2.8 8.1 7.3 3.3 4.1 6.5 3.8 7.2 3.9 3.6 4.6 4.5 3.5 10.0 3.5 2.1 2.7 6.0 4.7 4.8 4.9 2.2 5.4 0.1 3.9 0.0 1.6 0.8 3.0 1.7 3.5 3.7 3.1 3.2 2.2 3.5 2.3 3.4 0.1 2.4 1.8 1.7 1.6 1.9 2.3 2.3 4.6 2.6 2.1 2.2 2.2 2.2 2.3 2.1 2.2 2.7 4.2 3.2 3.9 3.6 2.2 11.6 4.7 3.3 14.2 2.8 4.6 5.3 2.2 1.5 3.4 1.8 2.1 3.6 5.7 1.9 0.0 2.1 2.1 3.3 3.6 3.7 7.2 1.3 2.9 1.8 3.0 2.9 4.6 4.0 2.5 4.0 4.2 2.2 1.7 0.0 3.2 2.5 2.0 1.6 2.8 0.3 2.8 1.7 1.8 0.0 0.7 3.3 4.1 1.0 2.6 2.4 1.9 1.5 2.0 2.8 1.5 1.4 2.0 5.6 0.0 2.5 2.3 9.7 8.1 6.8 10.9 6.2 3.3 5.4 3.4 1.8