Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122064583-122144308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 145.9;Hepatocytes: 113.9;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 132.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 41.5;NTERA-2: 55.3;SuSa: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020637, HPA020728, HPA020734" Enhanced Approved Nucleoplasm,Vesicles,Mitochondria Yes No 19000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020637: AB_1844415, HPA020728: AB_1844416, HPA020734: AB_1844417" "unprognostic (4.84e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-4)" "unprognostic (6.08e-2)" "unprognostic (1.49e-2)" "unprognostic (8.00e-2)" "prognostic favorable (9.81e-4)" "unprognostic (4.48e-3)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.99e-1)" "unprognostic (7.76e-3)" "unprognostic (8.56e-3)" "unprognostic (1.55e-1)" "unprognostic (6.50e-2)" "unprognostic (2.67e-1)" 9.7 5.9 10.0 1.8 12.2 0.2 8.4 10.3 14.4 8.2 15.5 5.2 0.9 9.5 7.5 3.2 11.7 2.1 9.2 9.4 10.6 13.9 44.3 6.3 1.4 11.6 11.0 25.2 4.8 7.1 3.5 3.2 11.4 5.4 1.4 3.7 3.5 4.8 8.6 2.8 3.6 4.4 10.1 2.9 5.5 2.2 11.0 1.5 4.7 6.2 1.4 6.9 6.2 11.8 0.1 0.0 21.9 41.5 27.3 13.5 9.4 5.4 8.0 7.3 9.1 12.6 0.1 0.0 0.2 6.6 8.3 4.1 33.5 16.8 9.6 0.0 12.2 9.4 4.3 12.5 22.0 0.0 2.9 12.2 0.5 9.2 7.1 18.9 19.8 12.1 2.7 15.5 5.1 0.1 0.9 0.0 55.3 0.1 1.7 11.8 16.3 0.3 5.3 2.4 2.7 0.7 1.5 0.0 5.3 37.8 0.5 0.0 8.1 13.6 3.4 7.0 8.3 3.5 3.0 0.0 4.9 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.0 12.2 10.3 14.4 9.4 10.6 11.6 11.0 11.4 10.1 11.0 11.8 16.0 9.6 37.8 145.9 2.1 6.2 9.0 2.8 14.8 7.0 8.7 6.3 9.7 14.3 5.6 14.7 16.7 11.6 1.5 0.6 0.0 2.7 12.2 4.1 24.0 11.7 3.0 5.2 5.0 1.8 3.3 14.4 5.6 7.7 3.8 18.1 24.7 113.9 1.5 11.8 4.4 2.6 2.0 2.2 2.5 7.4 19.0 1.4 12.4 35.6 0.0 8.9 0.0 106.1 132.5 2.3 2.5 24.5 1.6 4.7 5.4 8.6 0.9 3.3 19.7 38.9 15.8 12.4 2.4 7.8 4.7 5.1 2.1 8.0 1.9 4.8 ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Hepatocytes: 175.5;Kupffer cells: 169.1;Langerhans cells: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HSkMC: 34.1;U-87 MG: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057283, CAB069889" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Vesicles" "CAB069889: AB_10002789, HPA057283: AB_2683396" "unprognostic (1.58e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (2.80e-1)" "unprognostic (7.47e-3)" "unprognostic (1.85e-1)" "unprognostic (9.22e-2)" "unprognostic (9.80e-2)" "unprognostic (2.04e-1)" "unprognostic (7.28e-3)" "unprognostic (2.14e-1)" "unprognostic (4.78e-2)" "unprognostic (1.04e-2)" "unprognostic (2.00e-3)" "unprognostic (2.51e-2)" "unprognostic (6.71e-2)" "unprognostic (2.57e-1)" 24.7 36.5 12.0 11.0 29.1 20.7 13.3 14.4 12.5 7.4 4.1 16.3 4.5 5.6 8.2 4.9 8.0 15.0 4.6 10.4 13.7 7.2 38.7 12.3 8.9 19.5 26.2 8.9 4.0 1.8 2.5 22.7 19.0 4.1 9.9 3.7 5.7 5.0 10.9 13.4 8.1 7.6 16.4 7.1 6.7 3.6 27.3 11.0 5.1 3.4 5.4 19.7 7.6 20.7 0.0 5.6 4.6 0.0 13.1 4.9 4.1 5.9 22.6 1.9 2.1 0.8 0.8 8.2 6.4 5.9 21.7 0.0 2.5 0.3 1.7 0.0 0.0 0.9 1.9 20.3 23.5 0.0 13.8 34.1 1.5 22.7 0.4 21.6 2.2 0.7 0.0 20.2 0.5 0.8 5.2 11.1 6.5 1.2 1.7 0.1 0.0 0.4 3.7 3.9 0.7 0.2 6.2 1.0 1.2 8.7 0.1 4.1 2.1 6.0 0.4 8.0 6.5 7.9 4.0 4.8 79.0 0.0 0.1 2.4 0.8 13.1 0.1 1.0 0.2 1.2 0.3 0.0 0.2 1.5 0.6 0.0 10.6 0.1 1.7 0.1 0.1 0.2 12.0 29.1 14.4 12.5 10.4 13.7 19.5 26.2 19.0 16.4 27.3 20.7 35.8 105.8 9.3 71.5 21.1 29.7 5.9 6.3 61.5 18.4 4.6 7.0 8.9 22.8 11.7 11.0 47.9 31.1 2.4 8.4 0.0 4.5 1.9 17.1 76.0 18.7 9.1 1.3 8.1 1.5 6.9 44.0 14.3 29.4 46.9 3.6 31.4 175.5 75.0 0.0 22.5 2.2 8.2 169.1 109.5 2.5 31.1 74.8 26.6 38.4 6.4 0.5 0.0 57.8 7.7 4.9 5.0 28.2 2.2 2.6 0.1 18.0 8.4 6.7 46.0 24.3 23.4 1.0 1.8 17.1 19.5 8.9 6.5 39.5 3.2 13.3 ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 231.5;Granulosa cells: 117.3;Leydig cells: 502.6;Microglial cells: 162.1;Oligodendrocytes: 406.6;Skeletal myocytes: 216.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 31.9;ASC TERT1: 69.6;HSkMC: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" 39.1 30.5 12.6 2.8 28.1 0.0 21.3 21.0 18.3 10.0 9.6 16.4 6.2 11.9 15.6 7.6 23.7 16.9 42.1 13.6 16.1 9.5 33.7 18.2 1.1 28.2 19.8 51.5 5.7 3.8 11.1 9.0 29.0 9.5 16.9 9.2 14.8 8.6 12.3 6.2 11.8 6.6 20.7 12.4 14.3 19.5 18.4 4.5 17.0 26.7 3.0 16.3 14.6 58.1 0.0 0.0 3.9 0.0 31.9 69.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 12.0 0.0 0.0 53.5 0.0 0.8 0.0 0.4 6.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 28.1 21.0 18.3 13.6 16.1 28.2 19.8 29.0 20.7 18.4 58.1 22.6 51.3 1.1 0.7 0.0 6.0 1.8 0.0 2.8 5.0 0.7 1.0 18.8 0.0 4.3 0.0 2.1 0.2 0.3 0.0 0.0 0.0 4.8 0.4 14.0 6.8 0.0 0.0 0.5 0.0 0.1 231.5 3.1 0.3 1.3 117.3 5.7 48.1 1.1 5.0 0.6 0.0 0.0 1.9 9.4 19.4 502.6 2.6 1.8 162.1 0.0 100.3 0.0 0.5 406.6 0.0 0.0 70.3 1.9 0.4 0.0 0.1 0.0 3.3 39.5 216.6 44.5 5.1 1.7 2.5 4.7 0.3 2.1 60.9 0.0 0.4 AC092718.2 ENSG00000260643 "Novel protein" 16 81053587-81096296 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 13.4" HPA041368 Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 14: REH - Unknown function" Vesicles "HPA041368: AB_10804001" "unprognostic (3.87e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (2.12e-2)" "unprognostic (8.06e-2)" "unprognostic (1.08e-1)" "unprognostic (3.95e-2)" "unprognostic (8.11e-2)" "unprognostic (2.85e-1)" "unprognostic (2.42e-1)" "unprognostic (3.94e-2)" "unprognostic (3.19e-1)" "unprognostic (2.69e-2)" "unprognostic (2.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.56e-3)" "unprognostic (3.03e-1)" 4.4 2.9 12.8 1.1 14.6 0.5 3.5 12.7 15.5 3.1 12.8 2.5 0.3 2.5 5.0 1.7 4.8 1.3 4.8 13.5 13.6 6.5 9.6 2.6 0.9 13.8 14.4 3.2 2.9 3.2 8.1 2.8 13.8 4.5 0.8 5.7 2.6 1.7 6.4 1.2 1.4 1.6 12.1 1.3 2.2 6.2 14.0 1.3 14.2 2.9 0.6 3.6 2.7 14.1 4.1 3.1 4.8 3.4 11.1 3.9 5.0 2.1 0.9 1.8 0.3 0.3 4.7 0.6 4.1 0.9 4.1 3.3 3.0 1.3 2.7 1.4 5.3 0.7 1.5 3.1 3.9 3.0 2.6 4.7 5.9 2.8 2.6 5.3 1.9 5.9 3.6 0.3 2.5 4.5 4.1 13.4 2.3 3.2 1.7 11.7 1.0 1.9 7.3 1.6 3.8 3.7 2.4 1.0 4.1 5.1 1.1 4.7 2.1 0.8 1.7 2.2 1.7 2.6 3.3 5.4 2.4 2.1 2.0 0.9 0.4 0.3 1.2 0.3 1.3 1.6 0.8 0.4 1.1 1.5 1.2 0.7 0.3 1.7 0.4 1.8 0.2 1.0 12.8 14.6 12.7 15.5 13.5 13.6 13.8 14.4 13.8 12.1 14.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Early spermatids: 19.3;Excitatory neurons: 12.4;Inhibitory neurons: 12.4;Late spermatids: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 120000000 "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 2.5 2.8 6.9 0.5 7.3 0.6 2.8 7.6 10.0 5.0 5.3 4.3 3.2 4.2 2.9 2.4 5.7 1.2 6.0 7.1 6.2 9.6 63.8 2.8 0.9 7.0 6.7 6.7 6.2 1.5 12.5 0.8 7.1 6.4 0.9 1.1 2.5 1.4 4.3 2.6 4.4 0.6 6.3 2.6 9.8 13.5 7.2 0.8 6.1 1.4 0.5 4.4 3.1 7.1 0.0 0.8 1.9 2.6 1.5 1.3 0.8 0.7 0.5 0.2 0.3 0.3 2.1 0.2 0.9 0.4 0.6 0.3 0.1 0.4 0.1 1.2 1.7 0.2 0.9 0.4 1.1 0.0 0.7 3.6 0.9 0.2 0.7 1.2 0.1 1.3 0.0 0.8 0.3 3.3 0.0 0.9 2.0 1.1 1.1 0.2 0.2 0.9 0.8 0.8 1.3 4.0 1.4 0.6 1.2 3.9 3.7 0.4 0.5 1.5 0.8 0.9 0.0 1.7 0.3 0.3 1.1 0.2 1.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.3 7.6 10.0 7.1 6.2 7.0 6.7 7.1 6.3 7.2 7.1 0.9 0.0 2.0 16.0 1.2 0.3 0.3 0.9 0.0 1.7 1.4 1.9 4.2 4.3 2.4 0.0 0.0 0.2 0.2 1.0 1.9 0.6 19.3 3.6 1.6 0.9 1.2 0.0 12.4 0.4 0.3 1.5 4.6 3.3 0.0 3.0 5.0 1.6 0.2 3.3 12.4 1.3 0.0 0.6 0.0 13.6 0.9 0.3 0.0 7.5 0.0 1.7 0.0 2.0 5.5 0.3 3.0 1.5 0.4 0.4 1.5 0.9 0.7 1.8 0.0 0.4 0.7 6.0 3.9 0.3 0.4 0.1 0.5 1.7 0.9 0.3 ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516066 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.3" "Cell type enhanced" "Detected in many" "Astrocytes: 221.7;Hepatocytes: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" NA NA 280000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA008904: AB_1849258" "unprognostic (3.70e-1)" "unprognostic (9.01e-2)" "unprognostic (5.32e-3)" "unprognostic (8.27e-3)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (8.15e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-2)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-3)" 8.1 9.5 22.9 3.7 21.5 1.9 10.9 21.6 19.2 10.9 43.8 17.1 7.2 15.1 9.6 5.2 21.6 7.6 10.8 21.8 27.2 10.4 58.3 5.0 1.2 24.5 34.7 8.9 12.5 12.2 7.3 9.2 24.2 12.0 17.1 5.9 8.2 11.5 17.6 4.4 7.0 14.0 26.8 2.7 9.6 6.8 25.6 5.1 25.1 11.4 2.6 5.7 4.9 24.1 19.6 14.4 36.5 30.6 29.0 13.0 32.7 23.5 25.7 15.5 8.4 16.5 38.1 3.0 11.7 11.2 21.5 21.1 23.2 33.4 22.1 0.0 16.3 1.7 11.3 37.0 9.7 17.1 0.0 12.3 40.9 10.1 17.5 29.5 23.7 12.2 17.9 0.6 26.1 8.7 15.3 0.5 40.3 18.3 14.6 70.7 74.6 4.9 18.8 19.9 27.1 31.3 9.8 0.8 16.7 25.1 10.1 14.8 0.5 23.2 16.6 10.6 22.4 2.7 0.0 0.1 12.7 12.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 22.9 21.5 21.6 19.2 21.8 27.2 24.5 34.7 24.2 26.8 25.6 24.1 2.4 3.2 4.1 221.7 1.1 0.0 13.4 0.0 11.4 11.8 12.0 14.6 14.5 21.5 5.0 16.5 20.9 21.8 2.3 18.8 0.0 18.4 7.9 50.1 23.2 3.1 12.2 9.1 12.3 11.8 7.9 10.2 10.2 41.4 0.0 28.5 6.1 120.4 3.4 0.0 18.9 18.8 0.0 5.4 0.0 7.4 9.6 1.8 0.0 9.4 0.4 6.2 0.0 54.3 3.5 20.3 12.2 9.8 0.2 21.0 10.6 5.4 2.2 13.5 0.0 25.7 8.0 1.3 7.2 2.5 0.0 7.3 1.3 11.7 22.2 11.1 ADIPOR2 "ACDCR2, PAQR2" ENSG00000006831 "Adiponectin receptor 2" Q86V24 12 1688574-1788674 "Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 321.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043737 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA043737: AB_10964205" "unprognostic (1.52e-1)" "unprognostic (2.11e-1)" "unprognostic (2.44e-1)" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (1.34e-1)" "unprognostic (5.33e-2)" "unprognostic (7.66e-3)" "unprognostic (4.86e-2)" "unprognostic (1.61e-1)" "unprognostic (5.34e-3)" "unprognostic (2.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.15e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (5.85e-2)" 55.1 72.3 36.6 10.6 49.8 9.6 44.2 46.4 48.7 25.8 28.3 32.2 22.2 24.4 8.1 45.2 23.3 9.7 33.3 35.3 40.6 22.4 79.6 44.6 9.8 50.9 46.9 25.1 31.1 16.9 26.1 13.0 49.5 20.7 17.7 13.1 22.2 11.9 42.9 31.9 32.7 12.0 41.6 19.9 44.7 27.7 44.5 12.8 28.0 19.9 12.6 21.4 29.3 67.0 34.3 28.0 23.1 21.4 21.4 25.6 30.9 24.6 28.4 31.5 44.5 42.1 51.6 24.1 7.8 23.0 56.7 26.1 34.7 35.8 44.9 62.7 28.7 47.3 22.7 30.3 21.2 36.1 29.3 22.6 35.5 39.8 45.6 28.7 23.1 25.8 31.7 50.9 23.7 48.8 23.6 32.8 46.3 28.4 14.8 19.5 43.7 18.3 31.4 19.9 6.9 16.4 22.7 43.8 51.5 39.7 24.6 46.5 23.2 17.8 37.5 28.6 36.2 12.3 16.5 39.5 21.7 32.3 24.7 0.7 0.7 1.8 0.9 0.7 0.7 0.5 0.5 0.8 0.5 0.5 0.6 0.7 0.9 0.6 0.6 0.9 0.7 0.3 36.6 49.8 46.4 48.7 35.3 40.6 50.9 46.9 49.5 41.6 44.5 67.0 81.5 12.8 32.4 39.2 21.8 23.7 25.0 26.6 22.8 11.3 29.9 20.3 22.3 31.5 36.6 14.7 18.8 13.9 32.4 91.4 11.7 22.6 56.3 17.8 15.4 41.1 37.5 38.1 35.7 31.4 42.2 21.1 61.7 30.2 36.3 28.8 28.9 113.4 18.2 18.5 41.3 49.0 32.6 27.3 18.9 77.0 15.8 32.6 26.6 124.6 27.0 32.5 27.8 32.2 321.0 39.6 49.4 22.6 30.2 27.8 41.5 10.8 21.7 16.0 6.6 21.3 25.7 45.0 42.2 29.7 34.4 29.3 26.1 39.6 33.5 29.8 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187317-78207701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 173.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 118.3;Proximal tubular cells: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.4;intermediate monocyte: 16.7;memory B-cell: 5.4;myeloid DC: 7.6;non-classical monocyte: 11.0;plasmacytoid DC: 5.1" "Group enriched" "Detected in all" 5 "B-cells: 5.4;dendritic cells: 7.6;monocytes: 16.7" "Cell line enhanced" "Detected in all" "Hep G2: 186.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA023861: AB_1844636, HPA026536: AB_1844637" "unprognostic (3.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-2)" "unprognostic (5.78e-2)" "unprognostic (9.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.79e-2)" 14.6 7.6 52.8 11.7 76.1 10.8 65.5 67.3 66.2 15.2 35.5 15.8 17.9 15.3 13.9 18.7 22.9 19.0 22.5 52.6 60.5 88.8 173.2 27.1 12.0 74.4 71.3 31.9 59.3 9.1 9.1 26.7 66.8 28.3 18.8 4.0 38.7 18.4 19.2 32.9 15.5 13.4 56.6 14.6 22.1 13.2 68.6 8.9 15.0 14.4 13.4 13.2 19.0 114.8 21.3 29.4 25.4 23.3 27.9 32.5 13.7 29.8 16.8 20.4 24.5 31.5 17.2 65.8 19.2 22.8 11.9 17.8 43.5 26.0 28.5 41.9 34.6 53.2 35.2 186.5 24.4 44.4 26.2 43.8 26.9 23.9 31.0 33.5 38.8 19.6 54.7 22.4 16.0 20.9 34.0 67.2 20.9 51.1 49.8 38.3 25.9 79.2 27.9 19.3 56.2 41.5 25.5 75.5 24.4 25.1 22.8 42.3 19.3 31.2 20.5 19.9 21.4 33.8 24.2 68.0 25.7 21.5 8.2 1.7 6.4 0.8 0.7 16.7 1.2 5.4 1.1 1.2 7.6 2.1 0.6 0.6 1.8 1.9 11.0 5.1 1.1 1.8 52.8 76.1 67.3 66.2 52.6 60.5 74.4 71.3 66.8 56.6 68.6 114.8 17.9 16.0 16.0 0.7 9.7 26.4 19.8 11.5 79.6 1.2 44.7 34.3 13.2 58.6 12.1 64.4 4.2 12.9 2.1 15.1 17.6 11.5 0.2 21.3 14.5 16.7 13.1 11.3 7.7 8.5 11.2 18.6 23.9 23.8 2.5 9.5 17.9 118.3 10.1 1.7 4.0 26.8 10.2 20.9 20.7 2.7 22.4 21.9 30.2 6.5 8.8 1.6 2.1 3.0 74.2 7.8 27.6 21.8 25.4 15.7 17.8 105.8 14.7 1.7 0.0 15.2 18.1 1.5 13.3 52.1 41.1 11.5 4.3 21.6 30.6 14.5 AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1603.7" "Group enriched" "Detected in many" 9 "Cholangiocytes: 985.1;Hepatocytes: 2244.9" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 646.2;THP-1: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" NA NA 5940000 65000000000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" 11.7 14.6 252.9 2.6 259.8 0.4 4.4 267.5 243.6 9.7 138.2 5.6 2.5 3.2 1.9 2.6 6.0 92.7 154.7 236.0 242.1 52.5 1603.7 5.1 1.0 352.4 314.4 3.5 7.9 6.0 25.8 0.7 304.9 16.3 3.6 26.4 4.9 2.2 43.6 2.0 9.7 5.8 340.5 1.3 4.9 4.1 273.5 1.7 13.2 25.8 0.1 7.0 4.5 322.4 0.2 0.4 0.2 0.2 15.6 0.0 0.9 0.6 0.2 0.0 0.0 80.6 0.1 0.3 0.7 0.2 0.7 0.7 0.0 0.0 0.0 11.4 0.2 0.2 0.3 646.2 1.9 1.0 0.5 26.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 5.5 0.7 0.0 0.2 0.6 0.6 0.1 0.2 0.3 2.4 0.1 0.1 0.3 0.9 0.6 0.4 0.1 5.5 0.1 0.0 243.6 0.1 0.4 1.3 0.4 1.2 3.5 47.0 0.4 0.4 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.9 259.8 267.5 243.6 236.0 242.1 352.4 314.4 304.9 340.5 273.5 322.4 0.8 0.0 1.7 140.0 11.3 0.6 1.1 0.0 0.0 4.7 0.8 0.3 60.0 985.1 0.6 3.7 35.5 0.1 0.0 0.0 25.4 169.8 62.2 0.3 0.4 5.5 0.0 50.8 0.3 10.0 0.2 27.2 0.5 0.1 0.0 0.0 39.3 2244.9 2.1 3.3 1.5 1.1 0.0 56.9 0.4 48.5 4.1 0.9 8.8 5.6 0.6 75.1 0.0 3.5 6.8 13.7 1.2 3.4 0.0 26.2 24.2 146.9 0.1 49.8 13.1 7.2 94.1 0.4 0.4 0.0 0.0 0.7 3.9 0.0 0.4 1.9 AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 235.8" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 245.4;Proximal tubular cells: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060766 Approved Approved "Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA060766: AB_2684356" "unprognostic (2.70e-2)" "prognostic unfavorable (3.26e-6)" "unprognostic (4.27e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.34e-2)" "prognostic unfavorable (3.25e-7)" "unprognostic (1.91e-2)" "unprognostic (8.75e-3)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.74e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (9.11e-2)" "unprognostic (2.75e-1)" 42.0 29.8 43.7 10.4 44.6 31.6 30.0 43.3 46.1 17.6 48.2 23.0 46.6 14.4 33.0 34.1 34.4 24.5 54.1 44.1 49.1 102.0 235.8 19.9 10.7 45.0 43.4 34.7 31.0 31.0 36.6 11.9 46.4 22.7 18.8 33.9 19.8 24.1 23.7 16.8 45.9 15.2 47.1 20.1 20.8 15.7 51.0 6.8 42.9 32.5 14.8 29.4 26.1 52.5 32.6 25.2 20.6 56.9 29.7 22.3 7.6 28.3 57.1 26.8 61.9 37.5 81.5 20.0 40.5 66.1 41.7 42.0 26.5 79.2 64.2 67.2 63.0 5.6 35.6 157.3 40.8 46.0 2.7 32.9 76.7 35.7 129.6 88.2 10.9 30.8 4.0 67.6 59.3 45.6 14.2 9.8 40.8 37.4 27.6 20.2 61.6 36.6 100.6 77.6 75.5 42.4 35.5 33.2 17.2 36.0 31.7 96.0 3.0 25.2 27.8 22.7 33.4 99.6 95.1 2.1 59.7 9.5 26.9 12.0 6.2 9.6 6.6 29.3 15.1 9.6 12.4 10.6 33.0 5.6 13.1 10.0 11.3 11.8 35.4 2.9 9.7 9.2 43.7 44.6 43.3 46.1 44.1 49.1 45.0 43.4 46.4 47.1 51.0 52.5 40.8 16.0 27.7 114.9 22.0 25.0 51.8 82.5 27.9 68.3 69.9 65.4 73.7 72.9 66.9 51.5 25.0 79.6 8.6 12.6 52.8 60.3 22.4 99.8 25.9 32.8 39.5 29.3 204.3 31.5 10.5 42.2 26.0 83.1 36.8 90.9 36.8 229.6 32.7 53.8 245.4 33.3 59.0 40.1 42.3 7.0 32.0 37.2 55.2 100.2 18.2 74.3 8.2 105.1 172.9 25.8 65.2 38.4 47.7 35.3 232.9 261.5 69.1 36.9 32.9 41.7 50.8 5.6 17.3 53.1 45.7 108.1 18.5 61.5 42.4 53.2 ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 369.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 633.3;Proximal tubular cells: 197.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.5;Hep G2: 78.1;Karpas-707: 82.0;RPMI-8226: 45.0;RT4: 219.1;U-266/70: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 3000000 "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favorable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" 76.4 37.2 53.4 2.0 63.2 0.4 28.8 55.9 63.6 15.6 37.7 10.1 0.2 7.2 2.5 6.6 16.0 2.3 26.5 47.5 56.2 116.6 369.7 3.1 0.3 56.7 52.9 45.3 44.3 15.1 4.5 0.0 53.0 14.6 5.4 8.7 88.6 6.9 90.7 3.5 5.6 2.0 48.4 0.4 9.5 15.0 53.9 3.7 2.6 59.9 4.6 28.3 6.4 46.0 1.3 0.0 0.0 0.0 36.5 0.0 0.4 0.3 1.5 0.4 0.6 0.0 3.2 2.6 10.2 0.0 2.1 0.4 0.6 1.5 0.7 0.0 0.2 0.1 0.3 78.1 10.6 10.6 0.2 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 82.0 1.6 0.0 0.0 0.2 0.3 1.1 0.0 0.1 0.2 45.0 0.7 219.1 0.4 0.3 1.3 10.6 0.0 0.6 0.1 0.0 0.3 1.4 6.2 0.0 0.1 44.8 14.8 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 63.2 55.9 63.6 47.5 56.2 56.7 52.9 53.0 48.4 53.9 46.0 0.8 0.0 6.0 92.7 4.6 0.1 53.5 9.1 1.8 0.2 14.4 2.2 16.1 38.6 44.0 12.9 0.0 0.0 0.1 7.2 72.4 2.9 22.3 57.2 5.2 4.6 1.2 34.7 0.6 5.6 0.2 9.1 0.0 3.6 27.8 12.4 17.2 633.3 0.1 0.0 3.0 17.6 2.0 24.5 1.9 35.0 26.4 9.3 3.6 3.7 0.0 40.0 0.0 11.1 0.2 2.2 0.4 22.6 0.0 12.2 0.8 197.4 32.2 1.4 6.6 10.5 5.3 1.6 4.3 1.7 0.0 0.1 2.8 0.9 5.6 61.7 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Cell line enhanced" "Detected in many" "ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 303.8 102.4 139.7 39.8 146.1 29.2 77.2 136.5 163.5 25.0 123.3 73.3 73.7 30.1 21.3 73.6 32.3 37.4 111.3 132.2 139.7 177.7 857.7 111.6 18.7 140.7 144.9 42.0 23.3 2.6 23.3 7.0 141.1 34.6 72.3 29.2 32.4 29.5 130.8 127.9 74.8 30.2 143.0 20.6 101.5 13.0 151.8 27.1 30.8 165.7 52.9 50.0 29.0 144.5 8.8 13.1 18.7 31.9 86.8 13.0 60.9 9.3 16.8 4.3 3.1 23.5 12.1 0.5 45.3 20.8 11.9 16.2 0.1 4.6 2.7 0.6 6.1 0.7 8.4 64.7 97.0 0.9 0.9 23.9 22.6 14.8 0.3 17.7 26.9 0.9 17.9 3.0 4.1 0.5 1.0 23.4 24.8 152.2 2.1 0.6 0.4 1.9 31.4 0.6 7.5 23.1 22.8 201.0 0.2 33.7 20.3 92.1 1.1 0.4 16.5 0.6 0.4 5.5 3.0 25.7 22.0 0.8 0.4 6.5 212.0 51.1 0.7 93.0 0.9 6.2 0.3 0.7 213.2 5.2 0.7 0.5 10.7 3.4 25.4 70.6 0.5 123.5 139.7 146.1 136.5 163.5 132.2 139.7 140.7 144.9 141.1 143.0 151.8 144.5 27.7 147.4 242.7 51.2 22.6 60.0 205.2 311.1 80.8 78.7 35.0 23.7 378.9 165.8 243.1 66.2 18.8 62.4 48.6 260.3 399.2 127.5 4.3 27.8 24.5 66.2 55.2 42.1 11.7 218.0 127.5 103.1 200.3 47.7 30.9 29.0 139.6 857.0 129.2 35.3 18.2 231.0 101.7 278.5 124.1 10.6 79.9 189.3 35.6 26.2 940.8 130.2 8.2 14.1 6.8 130.2 366.5 149.0 12.5 84.4 384.3 882.0 89.4 42.6 46.0 46.0 67.6 3.0 3.9 105.1 124.7 42.1 13.1 81.0 272.6 150.4 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 200.4;liver: 436.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 83.7;SK-BR-3: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 58000 "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: " "unprognostic (1.17e-1)" "prognostic favorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 70.8 16.1 73.9 3.9 88.9 11.7 21.6 73.8 95.9 12.6 106.5 6.8 1.6 9.8 4.7 36.3 8.3 5.5 33.0 68.2 73.8 200.4 436.6 6.2 3.4 72.9 82.8 7.3 4.6 23.0 9.7 13.2 70.0 29.5 2.7 6.5 9.1 27.1 74.2 19.2 4.7 7.1 65.6 7.5 12.5 3.2 92.4 11.7 7.1 74.8 4.2 19.3 16.8 66.1 12.7 17.8 9.5 29.2 40.0 5.7 25.2 13.1 7.1 11.8 9.5 13.7 8.9 8.8 16.6 15.6 5.7 34.0 16.7 35.4 4.5 4.8 15.9 5.9 5.0 83.7 12.6 4.4 15.1 15.6 19.2 6.5 6.6 9.0 13.5 14.0 21.0 5.7 8.1 32.3 4.3 20.2 4.7 26.0 10.1 27.9 8.4 10.0 12.1 32.0 19.6 7.6 21.9 85.0 16.1 14.7 38.7 6.3 11.3 10.2 14.0 12.2 4.5 7.1 17.9 2.5 3.4 33.7 13.5 0.0 2.7 1.5 0.6 3.6 0.5 0.8 0.3 0.8 4.4 0.7 0.2 0.5 0.3 0.1 2.0 1.5 0.6 1.5 73.9 88.9 73.8 95.9 68.2 73.8 72.9 82.8 70.0 65.6 92.4 66.1 2.6 0.0 2.8 27.1 4.3 7.5 17.9 12.5 17.6 3.7 9.8 8.5 20.9 34.3 2.9 46.0 10.4 78.0 2.0 2.0 46.9 6.5 0.5 1.1 1.7 3.1 2.4 32.2 1.2 0.9 12.6 3.2 7.7 3.9 4.5 2.1 15.4 385.1 13.8 20.2 1.6 3.6 6.1 17.2 1.4 0.6 1.2 4.7 3.6 1.9 10.9 14.0 1.0 5.5 1.3 2.5 1.8 2.6 4.4 12.0 0.3 279.4 1.7 4.8 6.6 2.6 4.7 2.2 3.9 21.7 5.4 86.6 2.6 4.5 4.0 9.5 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 162.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 414.1;Proximal tubular cells: 302.1;Syncytiotrophoblasts: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 256.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 23.7 38.3 46.6 9.1 47.6 1.8 47.1 43.7 45.8 32.7 40.7 29.5 23.7 25.1 8.8 35.9 28.8 19.1 27.9 44.7 43.2 115.1 162.2 15.7 8.6 43.1 43.5 65.3 27.0 34.0 8.8 44.9 42.6 42.0 27.4 19.7 40.6 27.9 12.2 29.4 21.0 23.6 44.8 7.0 23.6 12.3 44.0 18.3 47.6 26.5 17.1 18.1 20.9 45.2 64.9 41.9 116.6 193.4 95.5 56.4 147.8 76.1 93.4 86.5 110.5 118.6 60.7 0.0 75.5 60.0 36.1 47.1 36.5 256.2 78.8 0.1 44.6 12.3 63.1 102.1 46.3 0.2 0.0 69.0 59.2 67.3 47.7 64.2 70.0 0.0 0.0 0.1 77.1 42.1 2.6 0.3 79.4 47.5 35.2 38.9 131.8 0.0 81.2 48.4 39.4 47.2 0.0 41.1 44.7 89.0 75.2 2.7 86.1 24.8 75.6 28.8 53.1 0.1 0.1 0.4 13.4 0.2 40.6 0.7 0.2 0.1 0.1 0.0 0.2 0.8 0.2 0.1 1.8 0.6 1.2 0.6 0.1 0.1 0.0 6.4 0.0 0.4 46.6 47.6 43.7 45.8 44.7 43.2 43.1 43.5 42.6 44.8 44.0 45.2 17.6 16.0 29.3 99.3 5.0 25.9 59.5 110.0 87.0 23.6 40.6 91.1 39.9 27.1 43.5 42.3 22.9 414.1 3.7 15.2 76.3 43.5 31.4 18.7 44.3 19.1 21.7 5.2 16.0 13.8 107.8 34.0 27.0 21.4 7.0 50.4 18.9 74.6 51.1 25.2 21.5 25.9 20.3 9.4 7.6 41.7 25.4 9.1 55.2 12.2 7.5 102.1 0.0 41.7 30.0 12.6 15.6 37.2 2.0 27.5 23.4 302.1 23.4 13.6 19.7 19.4 25.8 1.0 5.1 59.2 16.1 222.3 4.6 39.3 46.4 50.4 ALKBH2 "ABH2, MGC90512" ENSG00000189046 "AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase" Q6NS38 12 109088188-109093631 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011198, HPA045392, HPA051976" Approved Enhanced Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB011198: AB_261971, HPA045392: AB_2679309, HPA051976: AB_2681680" "prognostic favorable (6.67e-5)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (4.64e-2)" "unprognostic (4.55e-2)" "unprognostic (4.71e-2)" "unprognostic (1.69e-1)" "unprognostic (9.60e-2)" "unprognostic (3.63e-1)" "unprognostic (1.85e-1)" "unprognostic (6.39e-2)" "unprognostic (6.43e-3)" "prognostic unfavorable (1.41e-5)" "unprognostic (1.01e-2)" "unprognostic (7.88e-2)" "unprognostic (6.24e-2)" "prognostic favorable (8.67e-4)" 22.1 14.7 17.0 13.1 18.8 8.5 22.3 17.9 18.5 19.9 15.0 16.7 7.9 21.6 9.3 18.0 20.4 8.2 14.6 17.1 18.1 15.2 31.8 12.3 16.8 18.5 18.3 21.8 19.1 6.1 9.8 7.2 18.6 15.4 9.1 4.5 15.6 11.3 25.3 27.7 15.0 13.8 17.7 15.1 16.8 11.3 18.1 11.3 15.1 12.1 14.0 19.1 18.6 20.8 35.1 58.6 33.0 74.1 22.7 30.3 52.2 22.9 15.2 23.7 26.7 62.3 24.6 53.5 22.1 13.3 11.1 25.1 55.9 23.0 13.8 48.0 50.0 26.8 35.3 57.9 30.1 37.2 23.9 31.4 48.9 22.2 56.5 28.7 9.1 50.5 40.3 31.0 16.3 61.6 34.8 74.5 45.6 36.6 59.1 30.4 32.0 57.7 31.5 48.1 33.8 58.0 24.2 77.4 50.9 12.3 47.5 22.1 9.6 26.0 28.5 25.0 34.1 43.1 54.6 119.2 22.4 31.8 42.7 2.9 8.1 1.4 12.4 11.2 21.8 27.4 18.4 17.5 8.5 27.6 27.1 16.2 1.5 16.7 7.6 21.6 15.8 10.4 17.0 18.8 17.9 18.5 17.1 18.1 18.5 18.3 18.6 17.7 18.1 20.8 23.7 9.6 6.3 4.2 15.9 50.9 52.2 19.4 42.1 3.6 25.2 44.3 6.2 12.8 16.3 9.2 2.1 17.5 12.5 3.1 15.6 26.5 12.2 7.2 27.9 17.3 8.4 10.9 3.5 24.0 25.0 20.6 14.3 8.6 6.3 9.5 6.1 21.4 9.8 5.0 3.6 11.6 18.3 8.2 11.7 5.4 26.8 6.8 26.6 3.7 4.9 11.2 7.2 6.0 7.6 24.1 5.1 17.3 13.1 46.7 7.4 20.2 10.0 7.4 0.0 44.5 26.0 7.9 32.0 35.9 60.0 5.1 12.6 24.5 14.8 25.3 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 ARMC6 MGC19595 ENSG00000105676 "Armadillo repeat containing 6" Q6NXE6 19 19033575-19060311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 110.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041420, HPA041681" Supported Enhanced Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA041420: AB_2677469, HPA041681: AB_10793928" "unprognostic (2.01e-2)" "unprognostic (3.34e-2)" "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (3.55e-2)" "unprognostic (2.43e-1)" "unprognostic (8.98e-2)" "unprognostic (2.36e-1)" "unprognostic (7.04e-3)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-2)" "unprognostic (1.70e-1)" "unprognostic (3.73e-2)" "unprognostic (1.40e-1)" 11.9 16.6 20.4 11.4 20.4 16.7 11.7 21.6 27.8 13.9 19.8 12.4 10.0 14.7 6.1 18.7 11.7 6.9 17.9 21.2 21.7 16.9 110.5 11.9 15.8 22.9 21.2 12.0 11.2 11.9 17.8 8.8 22.7 15.6 8.9 7.7 13.3 8.0 21.3 12.7 12.3 9.1 19.5 17.8 12.3 24.0 20.3 23.2 19.4 18.2 12.4 14.4 12.6 20.8 64.1 42.8 30.7 38.0 14.5 24.7 39.7 40.3 23.5 64.5 47.7 59.8 56.0 96.3 63.8 34.1 23.8 31.8 73.7 47.8 35.5 20.4 104.0 48.5 39.0 49.0 32.0 87.1 54.3 31.2 44.9 44.0 30.7 14.5 41.6 56.3 86.4 36.0 36.0 78.0 93.2 70.5 71.5 71.9 86.8 76.3 27.7 68.9 31.9 42.6 70.5 30.6 32.4 41.1 33.9 20.7 35.0 54.1 27.2 33.0 28.8 47.3 83.8 27.5 53.2 93.2 27.3 117.1 44.0 10.6 19.0 5.3 22.1 20.3 16.6 13.4 12.0 19.3 28.3 15.1 15.7 18.0 3.8 30.6 16.7 18.2 23.4 18.3 20.4 20.4 21.6 27.8 21.2 21.7 22.9 21.2 22.7 19.5 20.3 20.8 7.1 0.0 5.9 4.6 10.7 6.6 6.8 9.2 9.1 14.1 11.5 11.4 5.9 17.2 8.9 12.9 12.5 20.5 21.3 12.3 7.9 16.0 25.5 6.3 11.8 10.2 15.0 13.7 4.0 10.7 20.3 10.7 12.2 9.6 1.3 11.1 8.2 52.4 20.7 5.0 5.0 10.9 6.1 15.6 6.0 47.9 10.2 9.2 5.4 0.0 14.9 16.4 20.6 5.0 5.5 10.8 10.8 8.2 10.3 12.4 10.4 12.3 4.5 17.9 13.1 7.4 9.1 22.0 31.0 10.0 10.1 13.0 10.3 16.5 17.3 5.5 ASPDH ENSG00000204653 "Aspartate dehydrogenase domain containing" A6ND91 19 50511600-50514690 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.1;kidney: 39.0;liver: 132.4" "Group enriched" "Detected in some" 6 "Hepatocytes: 135.8;Proximal tubular cells: 487.2" "Cancer enriched" "Detected in some" 13 "liver cancer: 24.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 13.6;MOLT-4: 16.5;SH-SY5Y: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042631, HPA042654" Approved Approved Nucleoplasm,Cytosol NA NA 200000 "Cluster 15: Liver - Metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA042631: AB_10794530, HPA042654: AB_10794383" "unprognostic (5.79e-2)" "unprognostic (9.47e-2)" "unprognostic (8.97e-3)" "unprognostic (6.13e-3)" "unprognostic (5.13e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-3)" "unprognostic (3.32e-2)" "unprognostic (2.87e-2)" "unprognostic (2.09e-2)" "unprognostic (2.87e-3)" "unprognostic (6.70e-3)" "unprognostic (9.65e-3)" "unprognostic (3.36e-2)" "unprognostic (1.07e-1)" "unprognostic (5.31e-4)" "unprognostic (1.99e-3)" 0.5 2.5 18.1 0.9 20.9 0.5 0.0 23.7 40.1 0.0 7.3 0.2 6.6 0.2 0.0 0.3 0.0 1.7 0.3 19.8 17.3 39.0 132.4 0.2 0.9 17.0 17.5 0.0 0.8 0.0 19.6 0.0 16.8 0.3 0.0 5.4 1.6 0.0 0.3 1.1 2.5 0.0 13.4 0.6 0.3 0.2 22.9 2.4 0.9 0.0 0.0 0.1 0.1 21.9 0.1 2.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 13.6 0.0 0.7 3.8 0.0 1.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 1.7 0.0 1.6 16.5 0.1 0.0 0.6 0.2 0.4 0.3 1.1 0.0 0.2 1.7 9.2 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 3.6 0.8 1.8 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 20.9 23.7 40.1 19.8 17.3 17.0 17.5 16.8 13.4 22.9 21.9 0.0 0.0 0.0 3.3 2.0 0.0 0.0 0.0 0.0 29.8 0.0 0.0 0.4 1.5 0.0 9.2 4.2 0.0 0.0 0.1 45.0 0.0 0.7 0.0 0.0 0.1 7.1 10.7 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 135.8 0.0 0.0 4.4 0.1 0.0 1.9 0.0 2.5 0.0 3.4 0.0 2.8 0.0 0.7 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 8.8 487.2 0.0 4.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 ATG12 "APG12, APG12L" ENSG00000145782 "Autophagy related 12" O94817 5 115828200-115841837 "Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013272, HPA068989" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB013272: AB_2533272, HPA068989: " "unprognostic (2.48e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-1)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.72e-2)" "unprognostic (2.87e-2)" "unprognostic (5.51e-2)" "unprognostic (9.36e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.54e-7)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (5.11e-2)" 15.5 10.5 12.3 10.7 12.7 11.3 10.2 12.9 16.9 12.0 10.5 10.4 11.6 10.8 11.9 11.3 9.8 11.6 9.7 12.6 13.3 7.1 18.4 10.4 13.6 13.2 13.2 12.0 9.5 7.4 8.7 13.6 13.7 10.8 11.1 9.6 7.9 10.9 11.1 9.0 11.9 12.7 12.7 11.2 8.8 9.4 12.8 14.0 8.6 12.6 11.6 11.8 8.8 15.0 20.7 10.9 26.3 24.1 42.9 57.4 20.0 34.9 38.3 22.6 36.5 15.8 16.5 17.8 14.5 32.1 35.3 11.3 20.5 29.4 36.4 93.2 20.2 11.5 13.0 14.8 33.7 12.8 22.0 43.0 31.5 25.1 29.6 26.3 27.6 19.0 16.8 24.4 43.5 13.5 27.2 20.2 17.9 15.7 23.6 19.8 25.4 25.7 15.7 13.7 25.8 27.6 37.3 14.7 36.6 20.0 20.3 19.2 28.3 41.3 18.9 38.2 36.0 18.7 31.5 28.9 37.7 27.2 39.6 15.4 11.5 19.3 11.8 13.6 16.5 12.3 14.3 11.7 10.3 12.2 14.6 14.1 20.9 14.4 17.4 13.8 12.3 11.0 12.3 12.7 12.9 16.9 12.6 13.3 13.2 13.2 13.7 12.7 12.8 15.0 52.5 44.8 41.0 17.0 82.8 85.8 65.4 81.6 44.3 42.3 46.8 36.1 45.2 38.6 56.9 25.8 77.2 61.8 92.3 50.3 37.2 60.6 28.7 49.0 60.7 55.1 41.8 23.8 28.5 81.6 134.1 75.2 36.2 55.8 96.9 48.8 47.5 57.9 68.2 30.3 26.5 54.5 59.0 72.1 69.8 14.9 64.0 53.7 53.4 19.7 76.8 34.1 99.9 26.7 35.5 105.5 45.8 53.8 50.1 68.4 56.3 44.3 49.7 59.2 26.3 39.5 50.5 50.0 45.1 40.0 84.7 88.7 78.8 45.1 46.0 78.1 ATOH7 "bHLHa13, Math5" ENSG00000179774 "Atonal bHLH transcription factor 7" Q8N100 10 68230595-68232113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;liver: 3.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Excitatory neurons: 1.7;Hepatocytes: 1.1;Spermatogonia: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SCLC-21H: 7.5" "Region enriched" "Detected in some" 9 "cerebellum: 28.7" "Low region specificity" "Detected in some" HPA027008 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027008: AB_10600783" "unprognostic (7.17e-2)" "unprognostic (2.81e-1)" "unprognostic (7.66e-2)" "unprognostic (1.86e-2)" "unprognostic (2.20e-3)" "unprognostic (7.40e-2)" "unprognostic (7.76e-2)" "unprognostic (6.16e-2)" "unprognostic (2.46e-1)" "unprognostic (9.28e-4)" "unprognostic (4.96e-3)" "unprognostic (1.17e-1)" "unprognostic (5.06e-4)" "unprognostic (1.72e-1)" "unprognostic (2.52e-2)" "unprognostic (1.36e-1)" "unprognostic (7.18e-2)" 0.1 0.2 1.4 0.0 1.5 0.0 0.1 3.0 2.0 0.1 0.7 0.2 0.2 0.2 0.1 0.0 0.1 0.0 0.0 2.0 1.0 1.2 3.0 0.0 0.0 0.8 0.8 0.1 0.4 0.0 0.2 0.0 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 7.5 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 3.0 2.0 2.0 1.0 0.8 0.8 0.8 0.8 0.8 1.2 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.9 0.1 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.0 1.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.3 0.5 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 BOK "BCL2L9, BOKL, MGC4631" ENSG00000176720 "BCL2 family apoptosis regulator BOK" Q9UMX3 2 241551424-241574131 "Plasma proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 218.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 100.8;Oligodendrocytes: 47.0;Proximal tubular cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Cell line enhanced" "Detected in many" "TIME: 65.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (6.16e-2)" "unprognostic (3.01e-2)" "unprognostic (1.24e-3)" "unprognostic (6.30e-2)" "unprognostic (8.63e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-3)" "unprognostic (1.16e-2)" "unprognostic (8.45e-2)" "unprognostic (2.33e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "prognostic favorable (1.09e-9)" "unprognostic (9.48e-3)" "unprognostic (6.81e-2)" "unprognostic (2.46e-1)" "unprognostic (1.09e-1)" 90.6 7.1 88.4 6.2 138.6 0.4 37.7 110.4 110.3 15.6 51.0 38.0 8.1 34.2 16.3 29.5 18.1 22.7 6.3 77.0 87.8 20.5 97.0 20.1 3.7 146.6 120.6 9.9 16.3 3.8 4.7 5.7 127.1 28.5 5.0 1.2 11.8 25.5 2.6 20.0 9.4 20.4 98.5 6.5 21.5 7.7 115.4 1.1 11.0 3.2 3.4 34.9 18.6 218.8 36.0 8.8 15.7 36.2 26.3 15.6 4.4 28.6 11.3 36.9 37.9 16.2 14.6 0.1 9.7 51.0 9.0 32.9 1.7 28.9 13.8 0.1 0.3 0.1 9.3 42.2 21.8 0.2 1.3 15.9 29.2 15.5 4.4 27.8 44.6 2.4 6.4 0.1 36.7 46.0 0.2 0.2 9.9 40.0 26.8 0.4 25.9 0.2 24.2 0.9 14.0 5.4 13.2 8.5 23.3 18.3 24.4 1.3 65.0 0.1 52.8 0.7 3.2 0.1 0.1 0.1 0.1 0.0 2.1 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.7 1.0 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.6 88.4 138.6 110.4 110.3 77.0 87.8 146.6 120.6 127.1 98.5 115.4 218.8 22.5 6.4 32.1 0.3 0.5 7.1 11.5 8.6 5.2 0.2 19.4 10.5 10.2 32.9 6.3 11.0 0.0 2.0 2.5 5.8 15.6 23.2 0.2 6.6 17.6 15.6 11.4 5.3 0.8 11.1 10.5 10.9 5.6 14.4 0.0 2.6 12.5 100.8 0.7 0.0 1.5 3.7 2.0 4.7 1.2 1.5 6.2 0.7 1.8 4.7 0.0 3.9 6.2 7.5 47.0 27.7 2.8 10.5 0.9 26.3 7.1 41.9 1.5 1.3 0.0 11.7 11.2 0.3 8.2 19.8 12.8 6.2 1.6 3.4 6.1 15.1 C2orf72 LOC257407 ENSG00000204128 "Chromosome 2 open reading frame 72" A6NCS6 2 231037523-231049719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.6;liver: 18.7" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Cholangiocytes: 47.1;Hepatocytes: 129.1;Oligodendrocyte precursor cells: 45.8;Paneth cells: 51.3" "Cancer enhanced" "Detected in many" "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;CACO-2: 2.2;EFO-21: 3.3;OE19: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044962 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "HPA044962: AB_10960863" "unprognostic (4.90e-2)" "unprognostic (7.03e-2)" "unprognostic (2.15e-1)" "unprognostic (7.44e-3)" "unprognostic (2.88e-2)" "unprognostic (6.41e-2)" "unprognostic (3.38e-1)" "unprognostic (6.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.84e-1)" "prognostic favorable (5.27e-4)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (2.78e-1)" "unprognostic (7.23e-3)" "unprognostic (2.70e-2)" "unprognostic (5.19e-2)" 0.0 0.0 6.7 0.0 8.2 0.0 0.3 4.3 8.8 0.0 0.0 3.0 0.6 0.0 0.1 0.0 0.0 0.4 0.0 8.7 6.2 0.2 18.7 0.1 0.0 8.4 12.1 0.0 1.4 0.2 1.1 0.9 6.0 0.5 0.7 0.0 0.1 0.0 0.0 0.1 1.1 0.0 5.8 0.0 1.5 0.1 14.6 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.5 0.4 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 1.0 0.5 0.5 0.6 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 8.2 4.3 8.8 8.7 6.2 8.4 12.1 6.0 5.8 14.6 6.1 0.0 0.0 0.0 163.2 0.5 0.1 0.1 0.0 0.0 1.9 5.9 6.0 0.5 47.1 0.0 0.0 0.0 1.8 0.2 32.8 1.9 3.9 13.6 0.1 0.2 0.2 4.9 10.7 33.4 2.0 11.9 0.2 4.6 0.1 0.0 0.1 3.6 129.1 0.6 0.0 15.0 14.8 0.0 2.9 0.0 30.8 0.3 0.2 1.8 6.5 0.0 15.7 0.0 45.8 20.1 0.8 51.3 4.1 0.2 0.7 10.7 1.8 0.0 0.3 0.0 0.0 0.1 0.5 0.9 0.0 0.0 5.2 0.3 0.0 28.8 0.3 CERS2 "FLJ10243, LASS2, SP260" ENSG00000143418 "Ceramide synthase 2" Q96G23 1 150960583-150975003 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 732.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027262, HPA078737" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "Nuclear membrane, Endoplasmic reticulum" "HPA027262: AB_1852717, HPA078737: " "unprognostic (1.01e-1)" "unprognostic (2.70e-3)" "unprognostic (3.72e-2)" "unprognostic (1.29e-2)" "unprognostic (8.23e-2)" "unprognostic (2.03e-2)" "unprognostic (7.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-1)" "unprognostic (4.05e-2)" "unprognostic (8.17e-3)" "unprognostic (1.11e-1)" "unprognostic (2.63e-2)" "unprognostic (1.56e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" 95.0 307.2 126.3 53.1 171.3 80.1 100.1 170.2 165.7 96.8 141.7 81.5 94.5 79.9 89.6 46.2 94.1 97.1 71.8 125.5 144.8 261.4 732.2 135.0 56.4 201.5 168.5 104.4 129.3 159.4 84.7 113.8 192.1 83.2 88.6 38.1 61.5 82.7 37.5 46.9 102.8 99.2 158.7 65.1 128.0 49.8 157.2 67.5 161.4 57.3 69.9 91.0 70.7 223.7 154.3 175.8 138.1 277.9 395.1 237.1 100.8 153.1 217.9 278.1 189.1 188.4 248.5 137.7 244.3 242.4 174.6 165.5 195.5 160.7 247.6 194.0 157.7 193.4 107.5 219.3 277.6 216.4 218.5 214.0 197.9 254.3 315.6 341.4 174.3 189.8 210.4 281.0 363.4 255.6 134.2 135.7 200.9 499.4 299.6 160.0 95.4 208.4 311.5 127.2 121.7 185.8 169.6 278.7 183.8 172.1 335.6 296.5 145.4 196.4 93.6 180.1 267.9 189.5 229.0 841.7 222.4 91.0 200.7 212.1 80.2 136.0 76.9 43.7 93.6 34.6 70.3 78.8 69.5 31.9 60.6 60.1 86.5 63.4 32.8 70.1 86.7 88.5 126.3 171.3 170.2 165.7 125.5 144.8 201.5 168.5 192.1 158.7 157.2 223.7 46.3 67.3 67.9 8.8 23.1 24.1 38.2 37.0 18.2 7.5 52.8 27.6 2.8 120.1 23.2 53.3 4.2 77.8 40.2 60.7 13.7 104.6 7.5 24.9 39.9 47.9 24.6 24.8 5.5 92.8 42.4 44.2 16.3 29.7 36.8 33.0 38.9 200.5 55.9 3.3 5.9 29.3 30.5 45.2 35.2 7.9 56.2 54.5 37.4 5.6 39.4 26.5 26.8 7.5 51.3 103.7 32.4 40.3 29.2 52.4 98.8 81.7 21.2 9.9 39.5 37.2 33.8 13.8 6.8 13.9 15.6 54.2 34.3 39.0 29.1 34.2 CGNL1 "FLJ14957, JACOP, KIAA1749, PCING" ENSG00000128849 "Cingulin like 1" Q0VF96 15 57375967-57550717 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 87.2;Astrocytes: 79.7;Hepatic stellate cells: 58.5;Hepatocytes: 65.5;Microglial cells: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 52.7;SuSa: 37.6;TIME: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013500, HPA056911, HPA069214" Enhanced Supported "Nuclear bodies,Cell Junctions" No No "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" "Nuclear bodies" "CAB013500: , HPA056911: AB_2683274, HPA069214: AB_2686102" "unprognostic (1.04e-2)" "unprognostic (2.42e-1)" "unprognostic (1.52e-2)" "prognostic favorable (3.55e-4)" "unprognostic (3.22e-1)" "unprognostic (1.51e-3)" "prognostic favorable (5.58e-4)" "unprognostic (4.32e-2)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (4.05e-2)" "unprognostic (1.91e-2)" "prognostic favorable (1.37e-6)" "unprognostic (2.26e-2)" "unprognostic (3.39e-1)" "unprognostic (1.88e-3)" "unprognostic (1.18e-2)" 5.0 11.5 23.6 1.5 23.0 0.0 19.8 19.8 18.5 32.0 47.2 3.2 1.2 17.8 4.4 11.0 8.9 2.8 20.1 18.6 24.2 68.3 36.0 21.0 1.1 28.9 28.2 5.8 18.6 9.6 4.1 28.8 27.7 28.7 2.3 12.3 32.3 16.2 0.7 11.5 2.5 10.8 20.0 0.4 15.5 6.6 29.9 4.6 19.8 1.9 3.2 8.9 20.2 15.7 0.0 1.3 13.1 0.0 0.0 0.0 0.2 0.2 2.9 1.1 2.4 8.4 0.1 0.0 11.4 1.7 1.9 0.0 6.2 0.1 1.8 0.1 1.0 0.1 0.1 5.7 0.2 0.1 0.0 0.4 0.4 1.3 0.0 4.4 52.7 0.5 0.0 0.0 2.1 2.4 0.0 0.2 6.5 3.7 0.6 0.1 6.6 0.3 4.4 0.0 0.3 0.7 0.0 5.1 0.0 37.6 0.5 0.6 32.5 0.0 3.3 0.1 1.9 0.0 0.0 0.0 0.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 23.0 19.8 18.5 18.6 24.2 28.9 28.2 27.7 20.0 29.9 15.7 3.9 51.3 87.2 79.7 0.2 4.6 13.4 5.1 4.6 0.4 27.4 27.1 21.0 10.0 11.7 22.0 0.0 1.0 1.6 0.9 41.1 9.9 3.0 11.0 9.4 21.8 13.1 2.7 0.7 13.2 1.0 17.1 11.2 11.8 1.3 3.5 58.5 65.5 0.3 0.0 1.9 3.7 18.3 1.6 4.9 18.1 19.9 0.9 7.2 156.4 0.6 43.7 0.0 11.1 1.5 4.3 1.2 27.8 0.0 18.6 0.2 39.4 2.2 1.4 0.0 6.6 2.3 0.6 0.6 0.8 2.4 1.4 1.2 0.6 2.2 7.0 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHRNA4 "BFNC, EBN, EBN1" ENSG00000101204 "Cholinergic receptor nicotinic alpha 4 subunit" P43681 20 63343223-63378401 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.8;liver: 58.0" "Group enriched" "Detected in some" 4 "Hepatocytes: 42.0;Horizontal cells: 139.7" "Cancer enhanced" "Detected in some" "liver cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-2 OS: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "midbrain: 21.8;pons: 20.5;thalamus: 33.5" CAB034064 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 9: U-2 OS - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "CAB034064: AB_2080535" "unprognostic (3.40e-1)" "unprognostic (1.71e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-1)" "unprognostic (8.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.74e-1)" "unprognostic (2.10e-3)" "unprognostic (5.72e-4)" "unprognostic (9.02e-3)" "unprognostic (9.79e-4)" "unprognostic (6.77e-2)" "unprognostic (1.08e-1)" "unprognostic (3.81e-2)" 0.0 0.2 6.7 0.0 6.5 0.0 0.0 0.6 6.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.7 8.7 3.4 58.0 0.0 0.0 5.7 15.7 0.1 0.0 12.7 0.8 0.0 6.2 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.6 28.8 0.0 0.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 6.5 0.6 6.2 6.7 8.7 5.7 15.7 6.2 0.5 28.8 4.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 4.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 42.0 0.0 139.7 8.8 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.9 0.0 7.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 2.7 0.0 1.7 0.1 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941371-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 885.9;Syncytiotrophoblasts: 648.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 818.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" NA NA 43000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favorable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favorable (5.67e-4)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" 78.1 180.7 99.3 39.6 108.9 71.8 85.5 114.4 140.4 105.3 119.6 80.1 55.0 76.9 47.7 198.0 65.2 60.3 81.7 96.6 107.4 94.2 292.3 93.3 49.7 117.4 107.9 107.4 74.0 61.5 48.7 116.9 117.3 87.2 20.7 17.2 133.7 70.5 98.6 119.7 64.1 38.3 109.2 63.6 99.8 51.7 102.7 26.9 59.1 49.9 26.0 86.9 124.1 124.3 131.3 131.7 15.0 128.3 141.2 122.5 6.0 143.9 178.8 120.3 133.6 112.1 148.6 51.7 62.7 208.9 48.6 172.9 23.6 152.0 26.2 115.1 163.4 92.5 65.1 267.1 265.1 155.0 35.3 159.2 180.7 104.3 101.3 116.6 113.2 82.0 383.2 109.4 100.6 818.5 63.4 267.9 32.4 361.1 42.9 88.2 127.9 72.8 129.0 404.5 60.4 53.8 47.7 405.7 125.7 7.6 84.0 436.6 137.5 212.7 82.2 71.0 109.6 37.5 18.0 41.2 236.0 211.3 152.5 62.2 312.2 59.6 77.9 218.1 64.0 56.8 52.6 62.6 251.5 57.8 45.5 51.7 12.0 73.5 151.5 291.4 72.6 178.6 99.3 108.9 114.4 140.4 96.6 107.4 117.4 107.9 117.3 109.2 102.7 124.3 99.1 125.0 88.1 22.9 33.1 102.1 231.9 248.1 188.4 73.4 174.9 218.4 41.9 104.4 162.7 152.6 10.4 885.9 80.1 53.0 320.8 201.0 4.6 59.1 72.2 86.7 84.5 70.0 16.8 193.0 113.5 103.1 46.4 46.9 71.7 95.7 77.1 262.0 311.4 25.2 17.2 97.7 191.2 177.0 107.7 13.3 134.2 137.0 240.1 20.6 137.0 158.7 41.2 25.1 45.7 170.2 108.8 179.8 45.5 132.4 179.9 73.8 135.8 43.2 138.1 143.3 113.1 8.4 5.7 236.4 123.5 648.5 41.8 222.0 122.3 206.6 CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" 1.2 0.4 18.3 1.2 22.1 0.1 9.3 23.6 19.1 2.3 8.4 19.0 34.1 1.0 0.8 13.1 0.9 2.0 89.7 14.7 19.4 3.0 146.2 1.4 0.2 20.7 20.7 0.0 2.2 0.0 0.9 22.3 18.9 3.3 21.3 3.5 14.5 0.7 25.3 8.9 83.4 1.8 20.2 0.1 4.7 0.6 28.0 0.5 0.1 6.4 0.7 5.8 3.6 21.8 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.7 0.1 1.2 0.3 2.8 0.0 0.8 0.0 3.5 0.9 0.0 0.9 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 3.2 0.0 0.0 1.5 16.9 2.6 0.0 6.3 0.0 3.4 62.3 0.9 3.8 0.1 16.4 0.6 0.1 4.1 0.0 0.0 2.2 2.5 0.0 0.9 1.9 0.1 0.0 0.5 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.3 0.2 0.0 0.4 2.9 2.6 0.0 0.4 0.0 0.6 0.0 0.4 18.3 22.1 23.6 19.1 14.7 19.4 20.7 20.7 18.9 20.2 28.0 21.8 0.0 3.2 4.1 35.6 0.7 0.4 1.7 5.5 7.4 0.0 5.1 3.0 91.4 11.5 28.9 0.0 0.0 116.2 0.1 26.4 0.0 9.5 22.7 3.1 1.7 1.3 9.0 0.0 0.1 0.9 9.3 2.3 4.1 7.7 0.0 1.5 0.0 58.3 7.0 0.0 0.4 18.7 6.1 0.8 0.3 23.3 0.0 0.2 0.0 1.9 0.6 12.5 0.0 29.7 68.5 2.0 18.1 0.0 0.3 1.5 134.6 2.5 20.1 0.9 0.0 0.7 1.0 0.3 0.2 7.3 2.3 240.9 0.2 0.4 24.1 2.1 DAO "DAAO, DAMOX" ENSG00000110887 "D-amino acid oxidase" P14920 12 108858932-108901043 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 71.4;kidney: 90.3;liver: 149.9" "Group enriched" "Detected in some" 8 "Hepatocytes: 46.1;Proximal tubular cells: 86.8" "Cancer enriched" "Detected in some" 9 "liver cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.1" "Group enriched" "Detected in some" 10 "cerebellum: 66.4;pons and medulla: 20.2" "Low region specificity" "Detected in all" "HPA038653, HPA038654" Enhanced "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038653: AB_10673016, HPA038654: AB_10673285" "unprognostic (1.50e-1)" "unprognostic (5.61e-2)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "unprognostic (2.18e-1)" "unprognostic (2.99e-2)" "unprognostic (2.31e-3)" "unprognostic (8.02e-2)" "unprognostic (2.88e-2)" "unprognostic (9.59e-2)" "unprognostic (9.07e-2)" "unprognostic (7.13e-2)" "prognostic favorable (4.11e-4)" "unprognostic (3.44e-3)" "unprognostic (8.96e-2)" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" 0.1 0.0 0.9 0.0 6.9 0.0 0.0 71.4 1.6 0.0 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.3 90.3 149.9 0.2 0.0 41.9 14.8 0.0 0.2 0.0 0.0 0.0 29.5 0.0 2.0 12.0 0.0 0.0 0.0 0.0 0.0 0.1 44.0 0.1 0.1 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 59.1 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 6.9 71.4 1.6 0.8 3.3 41.9 14.8 29.5 44.0 4.3 59.1 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.7 0.0 4.6 3.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 46.1 0.2 0.0 1.2 0.0 0.0 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.7 0.0 0.5 0.1 0.0 1.2 0.0 0.0 0.0 0.0 86.8 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 0.4 0.0 0.2 0.0 DCUN1D4 KIAA0276 ENSG00000109184 "Defective in cullin neddylation 1 domain containing 4" Q92564 4 51843000-51916837 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 111.9;Oligodendrocytes: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036483, HPA036484" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles Nucleoplasm "HPA036483: AB_10670719, HPA036484: AB_10671843" "unprognostic (3.16e-2)" "unprognostic (2.65e-1)" "unprognostic (2.77e-3)" "unprognostic (1.41e-1)" "unprognostic (5.61e-2)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (1.37e-1)" "unprognostic (8.47e-3)" "unprognostic (1.61e-3)" "unprognostic (3.88e-3)" "unprognostic (1.83e-2)" "unprognostic (2.93e-3)" "unprognostic (2.14e-1)" "unprognostic (5.25e-2)" "unprognostic (1.10e-3)" "unprognostic (1.40e-1)" 14.0 17.8 14.5 7.3 14.1 2.8 9.8 14.4 20.3 13.3 8.1 15.0 5.9 13.6 11.5 10.4 12.7 11.4 12.1 13.4 17.3 14.9 28.9 9.1 7.5 16.0 16.2 16.0 9.1 9.5 15.7 6.9 17.2 12.0 8.5 15.7 13.4 16.9 11.8 7.7 9.7 17.3 14.2 9.4 13.3 17.0 18.9 6.5 13.2 11.4 6.1 16.9 10.9 16.4 10.6 18.9 25.5 36.7 25.6 27.5 9.8 31.1 23.2 18.0 15.9 11.8 12.1 8.1 20.1 35.2 23.5 11.2 31.0 19.8 27.8 4.9 9.5 13.8 14.9 28.7 54.9 20.4 17.9 25.1 23.7 19.6 17.9 27.0 19.2 7.4 15.6 5.9 35.3 15.2 24.1 13.6 14.5 21.1 15.1 11.4 12.2 4.4 23.1 12.4 14.4 15.6 13.1 17.8 28.9 13.9 18.4 12.3 28.8 24.0 19.7 19.7 25.7 11.1 18.1 7.3 16.6 18.8 14.4 6.8 3.6 8.8 5.7 3.3 8.5 3.6 6.4 6.5 2.5 2.4 6.0 6.8 1.4 3.7 2.4 1.5 3.2 4.4 14.5 14.1 14.4 20.3 13.4 17.3 16.0 16.2 17.2 14.2 18.9 16.4 13.1 6.4 14.1 86.2 9.7 37.2 19.2 16.5 16.5 23.3 18.1 11.7 40.6 14.3 13.2 16.5 16.7 5.0 9.8 14.9 13.7 10.6 76.3 10.7 16.1 17.9 6.7 11.8 90.9 12.2 8.5 23.1 21.9 10.0 13.3 18.9 17.2 35.8 8.2 30.3 88.6 7.2 12.2 7.3 18.4 111.9 14.9 7.2 32.0 51.5 5.3 14.9 15.5 69.4 131.4 13.3 10.9 25.9 6.3 17.2 8.9 24.1 18.1 17.8 0.0 13.4 20.8 24.6 25.5 17.3 33.2 3.4 11.1 12.4 8.9 15.0 DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 77.9;Granulosa cells: 81.3;Hepatocytes: 156.1;Theca cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favorable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (5.67e-4)" 23.7 97.2 28.1 13.0 35.4 46.7 36.3 42.4 37.0 16.2 15.6 21.1 48.1 10.6 59.2 42.2 12.5 8.9 28.8 28.8 35.8 16.3 161.1 21.8 6.0 55.3 38.8 54.4 16.6 24.4 18.4 8.3 55.8 21.6 14.4 8.7 27.8 7.1 13.6 68.2 19.3 9.9 34.4 9.6 19.1 31.0 38.0 4.7 11.9 13.2 9.4 7.9 22.7 58.9 126.4 112.3 106.7 118.9 49.0 75.8 33.7 50.9 134.1 43.1 114.5 419.8 401.5 87.1 79.0 48.6 376.2 235.9 128.8 276.7 44.5 33.5 98.7 33.4 89.3 183.1 127.8 63.7 15.6 89.2 122.1 159.3 108.4 34.6 63.8 112.7 159.6 180.7 43.2 341.1 52.4 72.6 154.1 124.9 67.4 46.9 150.6 377.3 162.3 187.3 144.7 53.9 48.4 157.6 113.9 51.4 153.2 34.5 60.4 11.5 62.4 3.7 61.5 59.3 78.7 95.8 33.8 110.9 48.9 5.6 2.1 1.9 10.5 1.4 12.6 6.5 8.9 9.8 2.8 5.4 11.0 13.0 1.1 5.8 1.5 7.1 6.0 6.9 28.1 35.4 42.4 37.0 28.8 35.8 55.3 38.8 55.8 34.4 38.0 58.9 7.1 3.2 19.1 7.2 7.1 0.8 10.1 77.9 3.4 8.4 21.8 14.9 13.1 15.7 39.2 22.0 12.5 15.5 11.9 9.9 7.9 36.9 0.1 3.9 1.5 11.8 9.5 5.2 3.2 49.9 27.6 12.8 11.7 9.3 0.0 81.3 7.9 156.1 11.9 0.0 4.5 12.3 54.9 3.8 3.3 1.7 8.4 5.6 5.4 1.0 5.8 21.2 4.1 5.0 14.7 26.7 11.5 4.9 10.0 16.5 8.9 3.8 7.6 8.7 13.1 3.9 9.0 0.5 7.0 11.9 1.1 54.2 13.8 103.6 15.0 9.5 DIPK1A "FAM69A, FLJ23493" ENSG00000154511 "Divergent protein kinase domain 1A" Q5T7M9 1 92832737-92961522 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 30.6;Syncytiotrophoblasts: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015718, HPA017281" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "HPA015718: AB_1848405, HPA017281: AB_1848406" "prognostic favorable (8.96e-4)" "unprognostic (1.00e-1)" "unprognostic (6.17e-2)" "unprognostic (1.50e-3)" "unprognostic (1.43e-1)" "unprognostic (3.77e-3)" "unprognostic (3.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.19e-1)" "unprognostic (5.04e-2)" "prognostic unfavorable (1.45e-7)" "unprognostic (1.26e-2)" "unprognostic (5.99e-2)" "unprognostic (2.57e-1)" "unprognostic (1.66e-2)" 18.8 4.2 20.2 14.5 23.3 10.0 9.9 22.3 29.5 7.8 14.6 15.2 11.7 15.7 4.7 12.0 9.5 14.6 6.7 20.4 21.2 7.9 32.8 6.0 14.9 21.7 20.6 7.5 4.5 15.1 3.9 16.9 22.3 11.8 15.9 8.3 7.5 13.8 11.3 7.4 11.0 25.5 23.1 10.6 11.9 8.6 20.9 16.1 8.0 7.5 12.2 14.8 6.2 31.0 11.2 12.6 4.6 11.5 17.6 33.5 5.9 33.9 69.0 18.6 37.8 6.7 2.3 38.3 6.0 62.1 38.0 13.6 0.9 25.3 30.5 15.7 12.2 1.2 9.2 17.1 6.3 3.4 2.1 19.6 19.8 40.8 9.7 31.8 0.3 22.7 13.4 37.7 24.1 4.0 12.4 3.1 8.6 18.4 4.6 11.4 36.2 11.5 2.6 11.2 11.8 9.5 9.7 9.2 12.7 10.6 4.3 1.1 1.3 22.1 17.0 43.0 12.0 57.7 60.2 44.0 10.4 2.2 2.0 0.1 1.8 0.1 19.3 0.9 15.5 43.4 22.3 15.5 8.6 26.9 25.6 22.2 0.5 24.2 0.6 14.1 21.9 12.3 20.2 23.3 22.3 29.5 20.4 21.2 21.7 20.6 22.3 23.1 20.9 31.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 30.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 25.3 0.7 0.0 0.0 0.0 DNMT3L MGC1090 ENSG00000142182 "DNA methyltransferase 3 like" Q9UJW3 21 44246339-44262216 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.9" "Group enriched" "Detected in some" 6 "Hepatocytes: 20.8;Proximal tubular cells: 29.1" "Cancer enriched" "Detected in some" 90 "testis cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BEWO: 24.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055234, HPA066780" Approved Approved "Nuclear speckles" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA055234: AB_2682750, HPA066780: AB_2685719" "unprognostic (1.05e-4)" "unprognostic (1.91e-1)" "unprognostic (2.73e-9)" "unprognostic (2.77e-1)" "unprognostic (5.28e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 20.8 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934115-40035591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 66.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011811 Approved Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA011811: AB_2668543" "unprognostic (3.10e-1)" "unprognostic (4.78e-3)" "unprognostic (5.97e-2)" "unprognostic (7.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-2)" "unprognostic (6.47e-2)" "unprognostic (2.31e-2)" "unprognostic (5.11e-3)" 20.1 14.6 21.5 12.2 22.4 18.7 17.6 27.2 23.7 14.6 16.8 15.5 11.3 30.5 15.4 16.0 16.1 17.0 17.7 21.2 22.0 13.4 21.3 16.9 16.9 20.3 20.2 17.1 14.1 17.7 24.1 19.0 20.5 19.8 12.9 13.1 13.9 11.5 18.9 19.0 11.3 15.6 18.9 15.7 15.2 8.9 22.1 13.1 21.8 11.0 11.6 17.2 12.4 28.9 37.1 17.5 30.3 46.3 49.0 81.7 28.9 51.0 58.1 40.8 40.0 25.2 15.6 19.6 25.9 69.3 54.7 38.6 41.1 61.4 56.6 92.8 20.4 41.6 30.8 30.7 42.1 25.6 27.8 65.3 41.2 39.0 69.8 57.3 58.0 40.5 31.3 18.1 81.7 12.3 21.7 34.6 18.8 32.8 38.2 25.4 42.2 33.1 51.4 24.7 16.1 24.4 36.4 22.2 32.3 29.5 30.7 43.4 61.6 54.3 40.9 27.3 33.6 24.6 47.8 6.0 38.1 34.4 77.4 11.6 10.8 8.6 6.8 14.1 5.7 7.1 7.6 7.9 17.6 9.2 8.3 8.2 3.3 8.5 20.5 66.5 5.8 4.9 21.5 22.4 27.2 23.7 21.2 22.0 20.3 20.2 20.5 18.9 22.1 28.9 47.9 16.0 31.1 28.7 29.3 12.0 27.5 17.8 43.3 29.9 45.0 45.2 32.3 32.9 21.4 16.5 12.5 37.5 32.2 21.1 13.7 23.7 1.5 19.3 52.7 35.3 14.4 37.4 42.7 25.4 34.8 36.5 23.4 27.0 24.1 35.0 22.9 27.8 30.7 28.6 53.9 25.9 12.2 33.7 55.4 4.3 42.3 52.1 32.0 29.0 41.1 30.4 16.5 30.2 26.3 47.6 16.2 39.9 115.6 30.7 6.4 18.2 12.9 23.9 46.0 43.6 35.6 8.6 29.8 47.0 14.5 15.2 18.2 64.0 29.6 18.4 ELFN1 PPP1R28 ENSG00000225968 "Extracellular leucine rich repeat and fibronectin type III domain containing 1" P0C7U0 7 1688119-1747954 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2;liver: 14.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Endothelial cells: 5.7;Hepatic stellate cells: 7.1;Hepatocytes: 13.5;Inhibitory neurons: 19.2;Rod photoreceptor cells: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 31.2;U-138 MG: 18.5;U-2 OS: 27.0;U-2197: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066382 Approved "Nucleoplasm,Cell Junctions" NA NA 43000 "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "HPA066382: AB_2732744" "unprognostic (8.45e-2)" "unprognostic (3.39e-3)" "unprognostic (6.54e-4)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "prognostic favorable (9.68e-4)" "unprognostic (4.60e-3)" "unprognostic (1.63e-3)" "unprognostic (6.60e-2)" "unprognostic (4.14e-3)" "unprognostic (1.11e-2)" "unprognostic (2.31e-2)" "unprognostic (7.47e-3)" "unprognostic (8.63e-2)" "unprognostic (2.78e-1)" "unprognostic (4.07e-1)" 3.1 0.4 1.5 0.3 2.5 0.0 1.5 1.0 3.4 4.2 0.0 0.6 0.1 2.9 0.1 0.5 1.5 0.4 4.6 1.0 4.4 3.9 14.5 0.6 0.1 3.2 4.6 0.4 0.6 0.1 0.8 0.4 3.2 1.0 0.0 3.0 0.4 0.1 0.7 1.0 0.8 0.2 7.2 1.1 0.6 0.8 2.6 0.7 0.8 0.4 0.0 0.6 1.7 0.8 0.3 0.0 4.6 9.7 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.1 0.5 0.0 4.6 2.1 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 5.7 0.0 4.7 1.9 0.0 1.1 31.2 0.0 3.1 0.0 0.0 4.3 2.0 0.3 0.2 0.0 0.5 0.1 0.3 0.1 18.5 27.0 32.1 0.0 0.0 0.4 8.3 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.5 1.0 3.4 1.0 4.4 3.2 4.6 3.2 7.2 2.6 0.8 4.8 0.0 0.6 0.0 0.0 0.1 0.3 0.3 2.8 1.3 0.1 0.3 1.8 0.0 0.0 0.0 6.2 0.0 0.0 0.0 3.9 0.1 0.1 0.3 2.0 5.7 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.1 0.0 0.0 7.1 13.5 0.1 0.0 19.2 0.0 0.0 0.6 0.7 0.1 0.9 0.1 1.8 1.0 0.0 0.9 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.8 0.0 0.0 0.9 0.0 2.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 ELOVL2 Ssc2 ENSG00000197977 "ELOVL fatty acid elongase 2" Q9NXB9 6 10980759-11044305 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 52.5;placenta: 35.3;retina: 27.9" "Cell type enhanced" "Detected in many" "Astrocytes: 95.0;Cone photoreceptor cells: 29.2;Extravillous trophoblasts: 19.7;Sertoli cells: 19.7;Spermatocytes: 23.0" "Group enriched" "Detected in many" 8 "breast cancer: 11.9;glioma: 25.8;liver cancer: 24.0;melanoma: 14.2;prostate cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 31.2;HBF TERT88: 29.0;Hep G2: 23.4;RH-30: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 33: Fibroblasts - ECM organization" "prognostic favorable (6.73e-5)" "unprognostic (4.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.28e-5)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.89e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (6.92e-3)" "unprognostic (1.78e-2)" "unprognostic (1.04e-12)" "unprognostic (9.98e-4)" "unprognostic (8.86e-2)" "unprognostic (3.41e-1)" "unprognostic (9.47e-2)" 1.2 0.9 8.6 1.5 10.7 0.0 4.8 10.0 13.9 0.2 4.0 0.5 0.2 0.5 2.3 0.4 0.2 0.6 3.2 9.0 8.8 0.2 52.5 0.2 0.5 10.6 9.3 0.2 2.6 9.7 2.9 35.3 9.8 5.3 0.1 27.9 0.7 0.4 1.0 0.2 0.3 0.7 9.6 0.0 0.1 11.5 8.8 1.1 1.8 0.9 0.9 2.0 0.1 14.1 0.0 5.3 20.1 0.0 0.0 0.0 11.5 0.4 1.0 17.7 29.9 0.0 0.0 0.0 0.0 1.1 31.2 0.0 21.3 0.0 29.0 0.0 18.2 0.1 0.4 23.4 0.9 0.4 4.8 0.2 0.0 13.7 0.0 1.0 0.0 0.9 1.2 0.0 0.4 0.1 12.1 0.2 3.8 0.0 17.4 16.6 31.8 0.0 0.0 0.3 8.0 9.1 0.0 0.0 7.5 16.1 3.7 9.3 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 10.7 10.0 13.9 9.0 8.8 10.6 9.3 9.8 9.6 8.8 14.1 0.5 0.0 0.0 95.0 0.1 0.1 0.0 0.0 0.0 2.2 7.8 1.3 1.2 8.6 0.0 0.0 29.2 2.3 0.0 0.0 0.0 7.2 10.1 0.0 0.5 1.9 0.0 0.0 2.5 1.0 19.7 8.0 0.0 0.0 0.0 0.3 0.0 17.5 1.2 0.0 5.9 0.0 0.0 0.0 0.0 14.9 0.9 0.1 0.0 6.5 0.0 4.9 0.0 4.5 16.8 1.0 0.0 0.4 0.0 1.9 0.0 0.1 0.0 11.8 19.7 0.1 3.9 23.0 8.9 0.2 0.0 1.6 0.1 0.0 0.0 0.1 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810124-225845563 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1178.6;liver: 1705.1" "Cell type enhanced" "Detected in many" "Granulosa cells: 349.9;Hepatocytes: 757.6;Theca cells: 1042.6" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 1161.8;SiHa: 413.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favorable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 245.8 1178.6 233.5 23.6 252.5 22.7 163.7 239.0 249.3 188.3 345.8 82.0 102.2 108.1 97.6 159.6 153.8 96.5 94.0 221.3 233.7 110.7 1705.1 146.8 39.1 225.3 234.9 329.1 536.1 147.7 105.8 32.9 223.6 113.2 52.5 30.7 143.6 128.1 142.5 71.5 52.8 109.6 210.1 55.7 99.9 74.3 258.4 25.9 171.1 95.6 33.4 135.4 140.4 227.2 32.1 202.3 12.3 108.5 1161.8 120.2 24.3 29.7 49.2 28.1 35.1 38.8 293.6 1.3 128.7 147.3 30.6 38.1 32.7 16.8 12.1 7.8 46.5 21.8 83.5 282.7 129.8 12.9 15.1 109.2 40.0 74.6 6.3 116.5 22.1 13.4 14.5 27.3 50.4 30.3 13.5 31.0 61.6 178.1 79.4 27.8 15.2 92.9 91.1 132.5 98.3 13.0 413.0 192.1 51.3 32.1 131.7 43.5 46.8 41.9 35.4 54.5 59.0 9.1 38.9 4.1 63.5 14.2 59.5 0.0 2.6 0.1 0.2 0.7 0.4 0.1 0.3 0.2 0.6 0.2 0.5 0.3 0.2 0.7 0.3 0.9 0.3 0.8 233.5 252.5 239.0 249.3 221.3 233.7 225.3 234.9 223.6 210.1 258.4 227.2 196.9 0.0 14.0 41.1 5.7 19.6 121.8 244.2 74.0 8.8 29.7 27.4 1.2 102.9 255.5 51.5 29.2 46.6 3.4 34.5 17.6 95.3 10.2 142.9 32.2 82.7 10.8 7.0 3.1 73.0 7.6 175.6 30.5 93.4 5.7 349.9 88.2 757.6 149.1 1.7 5.0 17.5 103.7 30.9 28.7 28.4 311.3 25.8 42.7 23.4 9.6 99.2 0.0 7.1 19.4 45.5 27.2 159.1 9.5 40.4 63.4 128.9 174.3 10.1 223.5 29.3 146.9 4.4 5.1 129.0 17.6 22.8 4.7 1042.6 31.5 108.5 ETNPPL AGXT2L1 ENSG00000164089 "Ethanolamine-phosphate phospho-lyase" Q8TBG4 4 108742048-108763054 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.6;liver: 191.1" "Cell type enriched" "Detected in some" 8 "Astrocytes: 219.4" "Group enriched" "Detected in some" 23 "glioma: 7.9;liver cancer: 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 5.7;Hep G2: 2.3;NTERA-2: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044546, HPA072938" Supported Approved Nucleoplasm Yes NA "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA044546: AB_10962867, HPA072938: AB_2686560" "unprognostic (5.20e-3)" "unprognostic (1.33e-1)" "unprognostic (3.93e-1)" "prognostic favorable (9.52e-5)" "unprognostic (5.93e-3)" "unprognostic (3.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.32e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (1.93e-1)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (9.48e-2)" 0.3 5.5 155.6 0.1 155.6 0.0 0.1 98.4 144.3 0.1 47.4 0.0 0.2 0.3 0.0 0.1 0.0 0.2 10.6 124.4 145.8 9.1 191.1 0.1 0.0 100.7 118.1 0.1 0.0 2.9 1.9 0.0 110.3 0.0 0.0 1.7 34.4 0.1 2.4 0.0 0.0 0.0 101.2 0.7 18.3 0.5 119.8 0.1 1.1 1.5 0.0 0.0 0.0 101.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 5.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.6 155.6 98.4 144.3 124.4 145.8 100.7 118.1 110.3 101.2 119.8 101.3 0.0 0.0 0.0 219.4 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 14.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.4 0.0 0.0 0.4 0.0 0.0 0.5 1.5 0.4 0.0 0.0 0.7 26.8 0.0 0.0 0.6 0.0 0.0 1.6 0.0 1.7 0.0 0.0 0.0 7.5 0.0 8.5 0.0 1.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 7.9 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 EVI5 NB4S ENSG00000067208 "Ecotropic viral integration site 5" O60447 1 92508696-92792404 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027339 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" Vesicles "HPA027339: AB_1848308" "unprognostic (1.23e-1)" "unprognostic (2.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.65e-1)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "unprognostic (5.13e-3)" "unprognostic (7.43e-2)" "unprognostic (1.12e-1)" "unprognostic (9.11e-2)" "unprognostic (9.04e-3)" "unprognostic (2.25e-1)" "unprognostic (6.15e-2)" "unprognostic (8.30e-2)" "unprognostic (5.40e-1)" "unprognostic (6.38e-2)" "unprognostic (2.35e-2)" 5.7 8.1 5.9 4.5 8.3 2.7 4.4 8.5 5.8 5.9 8.2 4.8 4.3 6.4 4.6 4.0 5.1 5.8 7.1 4.2 7.7 5.0 16.4 7.1 3.2 8.1 6.2 3.8 3.8 7.9 3.9 12.1 6.8 5.3 5.5 4.9 4.5 5.6 2.9 5.0 4.0 7.1 8.6 4.5 6.4 9.6 6.3 1.3 6.6 3.6 3.3 5.5 3.8 10.9 5.4 5.9 9.1 8.9 14.5 18.2 8.6 12.2 18.5 8.2 9.4 10.4 1.4 2.4 16.8 14.0 15.2 6.1 8.6 9.0 14.6 0.2 3.3 4.3 5.6 6.2 14.2 3.1 4.8 11.5 7.2 14.2 8.5 23.9 17.9 0.2 7.7 3.8 13.9 2.7 0.3 3.6 2.6 3.5 4.8 2.2 21.7 3.2 6.3 15.5 3.4 7.0 14.4 7.4 16.6 9.8 3.6 7.1 11.8 9.1 6.6 12.2 8.1 5.5 3.4 3.8 6.0 5.0 7.6 0.9 2.7 2.8 0.1 1.9 0.0 1.2 0.1 0.0 1.3 1.2 0.0 0.0 3.4 0.1 2.9 0.8 0.0 0.4 5.9 8.3 8.5 5.8 4.2 7.7 8.1 6.2 6.8 8.6 6.3 10.9 27.2 60.9 29.9 91.4 18.7 43.5 29.3 23.0 18.2 24.5 20.5 17.7 51.8 22.8 32.3 16.5 25.0 48.4 7.5 22.9 17.6 27.9 3.0 67.8 39.4 31.2 22.1 11.4 158.4 29.9 26.0 42.5 42.3 26.2 13.3 21.9 43.2 52.4 32.2 30.3 149.3 27.0 14.2 54.0 27.0 5.8 28.3 45.1 26.6 114.3 48.9 28.5 5.2 112.6 199.6 68.4 19.3 54.2 28.8 28.1 21.8 20.1 46.9 25.4 13.1 51.4 56.4 37.4 42.4 21.2 50.0 65.5 5.5 60.9 20.0 32.1 FAM149A "DKFZP564J102, MST119, MSTP119" ENSG00000109794 "Family with sequence similarity 149 member A" A5PLN7 4 186104419-186172667 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 50.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.9;Microglial cells: 41.2;Muller glia cells: 29.1;Rod photoreceptor cells: 35.5" "Cancer enhanced" "Detected in many" "renal cancer: 9.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enriched" "Detected in single" 5 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 11.1;JURKAT: 8.3;MOLT-4: 8.5;RT4: 9.6;SCLC-21H: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044019, HPA055004" Uncertain Approved "Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA044019: AB_2732513, HPA055004: AB_2682667" "unprognostic (1.80e-2)" "unprognostic (8.44e-2)" "unprognostic (4.64e-2)" "prognostic favorable (2.67e-6)" "unprognostic (7.08e-2)" "unprognostic (9.12e-2)" "unprognostic (1.41e-3)" "unprognostic (1.06e-1)" "unprognostic (2.52e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-1)" "unprognostic (3.81e-2)" "unprognostic (9.92e-2)" "unprognostic (1.17e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" 11.8 5.1 22.7 1.6 25.5 0.1 6.0 20.1 26.5 7.4 25.9 13.0 5.7 7.4 11.9 11.2 13.7 14.8 7.2 28.7 22.0 35.7 50.4 5.4 1.4 23.4 22.7 7.5 25.7 9.4 5.7 2.2 23.2 9.5 7.6 26.6 9.9 16.0 10.0 2.7 5.2 7.2 23.0 2.3 14.8 5.2 24.7 2.1 3.4 11.4 1.7 11.1 5.4 23.2 0.0 3.3 2.9 0.1 11.1 4.5 0.1 0.0 0.0 0.3 0.3 0.0 1.9 0.0 1.6 1.5 2.9 0.0 5.3 0.0 0.0 0.1 0.7 0.0 0.2 0.0 0.7 0.1 0.2 2.0 0.3 0.2 0.0 1.1 0.0 8.3 0.0 2.5 1.3 1.7 8.5 0.4 5.1 0.0 0.0 0.3 0.0 2.1 1.7 9.6 14.2 3.9 0.1 0.0 4.7 0.9 1.0 0.0 0.9 0.2 1.6 0.0 1.7 0.0 0.1 0.0 0.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 1.2 0.0 22.7 25.5 20.1 26.5 28.7 22.0 23.4 22.7 23.2 23.0 24.7 23.2 1.8 0.0 1.5 8.1 0.5 0.5 2.4 0.4 1.2 11.8 0.6 1.0 8.5 22.8 4.4 5.5 45.9 0.7 0.0 1.6 5.9 9.5 15.3 17.4 3.7 1.8 9.5 2.7 8.8 5.4 0.9 5.0 4.1 16.7 0.0 0.4 1.4 13.8 0.2 1.7 12.4 3.7 2.0 1.3 1.8 5.6 3.4 2.6 3.6 41.2 0.0 29.1 0.0 7.5 0.5 5.0 4.0 4.1 2.9 2.3 0.8 8.5 11.1 35.5 6.6 2.5 3.3 1.0 4.7 1.6 0.3 0.8 1.1 0.1 3.3 2.8 FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 124.2;liver: 126.9" "Cell type enhanced" "Detected in many" "Early spermatids: 255.2;Hepatocytes: 130.9;Late spermatids: 557.6;Pancreatic endocrine cells: 89.2" "Cancer enhanced" "Detected in all" "glioma: 39.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 35.3;ASC diff: 34.7;HUVEC TERT2: 43.3;SH-SY5Y: 33.2;TIME: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Aggresome, Cytosol" "HPA051804: AB_2681617, HPA063581: AB_2685048" "unprognostic (2.57e-1)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.46e-3)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (8.28e-3)" "unprognostic (4.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (5.74e-3)" "unprognostic (2.40e-3)" "prognostic unfavorable (6.11e-4)" 34.5 124.2 55.4 2.9 54.6 0.0 26.2 59.8 69.0 7.5 40.3 5.9 1.1 4.2 2.7 24.9 3.8 12.2 11.7 58.9 56.0 11.4 126.9 4.6 1.1 64.6 57.5 38.3 11.9 36.5 11.2 2.5 63.6 11.8 1.8 10.4 9.0 3.2 4.1 4.9 3.4 5.4 56.2 5.4 5.6 27.3 59.2 0.4 5.9 4.0 2.8 6.0 8.0 56.1 0.0 0.3 19.9 35.3 34.7 21.2 0.3 8.1 16.3 5.8 5.0 1.6 0.6 0.0 0.9 25.9 7.5 0.0 13.3 4.9 5.0 0.0 2.2 1.7 0.1 18.7 12.9 0.0 0.2 18.2 2.3 10.0 2.0 26.0 43.3 0.0 1.9 0.0 21.3 0.0 0.0 0.1 12.4 0.0 0.7 0.0 0.0 0.0 3.4 0.0 0.3 33.2 0.2 0.0 0.3 2.6 0.1 0.0 39.7 5.4 2.4 2.1 6.3 0.0 0.0 0.0 29.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 54.6 59.8 69.0 58.9 56.0 64.6 57.5 63.6 56.2 59.2 56.1 14.8 0.0 0.5 5.2 0.8 3.4 3.2 0.4 5.7 9.1 8.3 12.8 2.4 14.3 0.2 0.0 4.2 0.2 0.4 0.0 3.9 72.9 255.2 1.6 18.8 10.9 0.0 2.7 20.1 48.3 0.2 17.3 6.1 2.0 5.7 5.9 10.0 130.9 0.5 0.0 18.7 0.5 0.0 3.2 5.3 557.6 15.5 1.0 3.6 5.6 1.0 23.7 0.0 10.6 2.1 89.2 0.0 11.7 0.7 11.9 0.0 0.4 0.2 12.9 0.0 34.4 15.6 5.0 8.4 1.4 2.4 0.0 1.5 1.0 0.1 1.7 GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.4;Extravillous trophoblasts: 2.6;Fibroblasts: 1.8;Hofbauer cells: 3.9;Syncytiotrophoblasts: 2.7" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;RPMI-8226: 3.4;SK-BR-3: 2.6;T-47d: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" 5.5 2.1 4.9 2.5 6.4 0.0 4.2 6.3 3.8 10.6 4.9 3.4 0.7 9.8 2.2 1.8 11.3 5.3 1.7 4.1 5.9 1.0 13.1 3.1 0.7 8.8 7.7 6.8 2.0 0.1 3.0 2.0 7.6 2.6 1.0 3.9 2.6 2.2 1.4 1.7 2.1 6.0 6.3 0.9 3.4 2.9 10.0 0.6 2.1 0.8 0.3 3.2 3.9 5.2 0.0 0.0 0.0 3.1 0.1 0.0 1.1 0.2 0.3 0.0 0.0 0.1 0.9 0.0 1.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.6 0.4 1.2 0.8 0.0 0.4 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 0.0 3.4 0.0 0.5 0.1 0.3 0.0 2.6 0.0 0.1 6.7 0.9 0.0 0.4 0.6 1.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 6.4 6.3 3.8 4.1 5.9 8.8 7.7 7.6 6.3 10.0 5.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 GCDH ACAD5 ENSG00000105607 "Glutaryl-CoA dehydrogenase" Q92947 19 12891160-12914207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 115.5;Proximal tubular cells: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043252, HPA048492" Enhanced Supported Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA043252: AB_2678390, HPA048492: AB_2680418" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" "unprognostic (6.79e-3)" "unprognostic (8.07e-3)" "unprognostic (8.20e-3)" "unprognostic (3.14e-2)" "prognostic favorable (7.28e-5)" "prognostic favorable (3.35e-4)" "unprognostic (1.62e-1)" "unprognostic (3.03e-2)" "unprognostic (7.50e-3)" "unprognostic (7.46e-2)" "prognostic favorable (6.79e-8)" "unprognostic (7.09e-3)" "unprognostic (3.42e-1)" "unprognostic (5.32e-2)" "unprognostic (1.59e-1)" 16.8 17.8 20.2 11.2 22.4 13.0 15.6 22.1 23.3 10.2 21.8 13.2 11.8 12.6 8.6 14.0 15.2 8.4 29.3 19.2 19.4 24.5 89.1 9.3 16.8 20.7 20.9 16.8 15.5 11.5 10.6 5.4 21.0 13.6 8.5 5.5 20.0 11.5 30.5 10.1 13.0 8.2 19.9 12.8 18.6 4.5 20.9 17.8 11.9 27.1 11.9 14.9 9.9 22.7 22.9 14.1 15.0 27.5 21.4 9.8 13.8 17.2 11.1 21.6 15.7 26.9 10.8 33.0 31.9 10.5 10.8 15.6 20.8 16.4 10.6 28.6 22.8 21.0 24.6 33.1 24.8 43.7 18.8 13.8 19.9 15.3 16.1 8.8 18.1 44.4 51.8 11.4 10.7 28.9 51.7 41.7 16.7 22.0 36.1 48.2 15.3 68.9 12.6 12.1 32.3 18.9 22.8 22.6 16.7 9.6 17.8 29.3 13.3 18.0 12.9 29.9 18.2 59.5 32.2 34.6 11.0 50.7 15.4 13.9 13.9 8.5 18.8 12.1 18.8 18.1 23.2 21.0 24.0 19.5 30.9 23.8 3.1 38.8 9.8 14.7 21.4 20.0 20.2 22.4 22.1 23.3 19.2 19.4 20.7 20.9 21.0 19.9 20.9 22.7 6.0 3.2 5.3 25.5 21.2 7.9 14.5 13.3 11.4 14.2 17.3 10.8 10.0 22.8 8.6 11.0 25.0 16.2 17.2 11.6 52.8 14.0 2.6 7.7 10.0 7.3 15.6 60.4 7.1 11.2 21.5 10.2 12.8 10.9 7.0 19.5 13.6 115.5 21.5 8.4 7.4 13.8 16.2 14.4 5.0 1.8 13.1 9.9 17.8 5.6 20.7 18.6 18.6 14.6 15.1 10.2 9.7 12.8 25.4 11.3 17.4 147.8 7.2 12.3 0.0 13.7 9.8 8.3 7.4 13.4 5.3 16.3 20.9 33.0 20.6 12.1 GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44143213-44198170 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 12.6;choroid plexus: 7.4;heart muscle: 8.8;liver: 21.5;pituitary gland: 23.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.0;Cardiomyocytes: 4.9;Fibroblasts: 5.2;Horizontal cells: 5.0;Smooth muscle cells: 3.7" "Cancer enhanced" "Detected in some" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.3;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 6.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007034, HPA007093" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "HPA007034: AB_1079050, HPA007093: AB_1079051" "unprognostic (3.09e-1)" "unprognostic (2.99e-2)" "unprognostic (3.32e-2)" "unprognostic (6.64e-7)" "unprognostic (8.00e-2)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (5.48e-2)" "unprognostic (8.11e-3)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (2.01e-2)" "unprognostic (3.24e-1)" "unprognostic (4.36e-2)" "unprognostic (1.53e-1)" 0.8 0.3 8.9 0.3 8.3 0.2 0.7 8.1 9.5 2.8 7.4 0.5 0.1 1.2 0.8 0.4 1.2 0.5 8.8 8.2 11.0 1.2 21.5 0.4 0.2 9.0 9.9 1.4 1.8 0.1 23.9 1.6 9.1 1.2 0.2 1.0 0.3 0.7 0.2 0.7 0.5 0.3 8.3 0.6 0.6 0.4 12.6 0.1 0.5 0.1 0.2 1.1 2.0 7.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.5 0.0 0.7 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 1.2 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.3 2.3 0.7 0.1 0.1 0.3 2.0 0.4 0.8 0.1 0.0 0.1 0.0 0.3 8.9 8.3 8.1 9.5 8.2 11.0 9.0 9.9 9.1 8.3 12.6 7.9 0.3 0.0 0.0 0.7 0.3 1.1 0.7 0.0 1.2 5.0 0.1 0.8 4.9 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.5 2.4 0.0 1.8 0.0 0.2 5.2 0.0 0.0 0.0 2.4 0.0 0.4 0.7 5.0 2.4 0.0 0.0 0.0 0.7 0.3 0.9 0.1 0.0 1.0 0.0 2.8 0.0 0.5 1.0 0.1 0.1 2.2 0.2 1.7 0.0 0.1 0.0 0.8 0.0 0.6 3.7 0.5 1.1 0.0 0.1 0.8 0.3 0.5 0.0 0.7 GJB1 "CMTX, CMTX1, CX32" ENSG00000169562 "Gap junction protein beta 1" P08034 X 71212811-71225516 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 100.9;liver: 335.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 114.4;Hepatocytes: 286.4;Proximal enterocytes: 118.8;Proximal tubular cells: 68.9;Undifferentiated cells: 66.1" "Cancer enhanced" "Detected in many" "liver cancer: 163.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 143.2;SK-MEL-30: 155.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012994 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB012994: AB_2533228" "unprognostic (2.09e-2)" "unprognostic (1.39e-1)" "unprognostic (8.78e-2)" "unprognostic (2.71e-3)" "unprognostic (2.70e-1)" "unprognostic (4.11e-1)" "unprognostic (2.92e-1)" "unprognostic (3.68e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (7.36e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.85e-6)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (7.79e-2)" "unprognostic (4.97e-2)" 0.1 0.0 27.1 3.7 63.2 0.0 6.4 76.5 37.6 8.8 12.7 33.9 44.0 1.7 22.5 0.3 27.4 41.5 0.0 27.3 40.9 42.9 335.7 2.4 0.0 90.6 64.4 0.1 83.0 0.0 0.1 0.0 76.0 11.6 23.8 0.0 37.7 7.5 0.0 0.9 34.4 1.8 50.0 0.1 16.4 10.2 56.9 0.0 0.1 0.1 0.0 0.4 0.1 100.9 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 25.5 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.3 0.0 5.1 0.2 0.0 0.2 0.0 0.0 155.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.1 63.2 76.5 37.6 27.3 40.9 90.6 64.4 76.0 50.0 56.9 100.9 0.0 0.0 4.8 0.3 0.8 0.6 0.7 0.5 0.0 0.0 7.7 2.4 0.1 114.4 2.7 9.2 0.0 0.0 0.1 50.2 9.8 34.1 0.3 8.2 3.4 0.6 9.6 8.0 0.2 58.9 0.0 0.1 15.8 29.0 4.5 0.0 3.3 286.4 0.0 0.0 0.2 29.4 2.0 4.8 0.4 0.4 0.3 0.8 23.2 0.0 0.6 0.0 0.0 1.0 51.3 32.3 53.4 0.4 0.0 2.6 118.8 68.9 0.1 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 0.0 1.0 0.0 66.1 2.8 GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532467-6645729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 173.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 31.3;Cytotrophoblasts: 79.0;Extravillous trophoblasts: 41.6;Hepatocytes: 120.5;Oligodendrocyte precursor cells: 52.3;Proximal tubular cells: 31.6;Syncytiotrophoblasts: 46.0" "Cancer enhanced" "Detected in many" "testis cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 235.7;CACO-2: 58.2;HMC-1: 45.6;RPTEC TERT1: 95.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria NA NA 740000 "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA002318: AB_1849700, HPA052887: AB_2681980" "unprognostic (6.73e-2)" "unprognostic (1.19e-1)" "unprognostic (6.50e-2)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-3)" "unprognostic (1.17e-2)" 0.3 0.3 15.3 1.4 15.5 0.5 0.8 14.7 23.7 0.4 12.9 1.0 0.8 0.4 5.2 3.2 0.7 0.8 0.1 14.8 14.4 38.2 173.5 1.0 1.6 14.0 13.6 0.3 0.1 0.0 4.9 15.2 13.4 0.5 0.4 1.6 1.1 1.0 1.3 4.5 0.8 0.0 13.1 1.2 1.0 3.5 15.8 0.0 5.1 0.1 1.2 1.1 0.1 15.3 0.6 4.9 2.1 25.6 0.2 0.4 235.7 0.1 0.0 0.0 0.1 58.2 0.5 0.3 5.6 0.1 0.7 0.4 0.0 0.7 0.2 1.2 13.4 0.2 0.3 38.3 0.0 0.1 45.6 0.0 0.1 1.8 0.3 1.0 9.0 4.3 0.0 0.5 1.2 1.5 0.9 0.2 27.5 4.6 3.8 1.3 0.0 0.5 95.4 1.0 22.6 11.7 0.0 21.4 0.3 13.9 5.3 0.1 3.0 0.6 0.6 2.6 1.3 1.1 34.4 0.1 0.8 2.4 5.1 0.4 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.0 0.3 15.3 15.5 14.7 23.7 14.8 14.4 14.0 13.6 13.4 13.1 15.8 15.3 0.2 0.0 0.0 17.6 1.9 0.0 0.0 0.2 1.2 0.4 1.5 0.6 0.7 11.5 0.1 31.3 0.0 79.0 0.2 0.0 5.9 0.0 12.6 5.4 0.5 0.6 0.0 0.0 21.6 0.2 41.6 0.3 0.0 10.7 0.0 1.1 2.2 120.5 7.0 0.0 15.9 0.0 0.0 2.8 0.3 10.8 0.3 0.4 0.0 1.9 0.0 9.6 0.0 52.3 1.8 0.1 0.0 0.0 15.1 0.0 0.0 31.6 0.0 0.4 0.0 1.7 0.8 4.5 5.1 0.4 0.0 46.0 0.8 0.0 0.0 0.1 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 294.1;Hepatocytes: 402.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 555.0" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 70.1 93.0 217.2 44.8 219.0 29.2 96.4 180.4 216.8 50.2 135.8 63.4 80.9 48.1 30.0 77.0 47.4 53.3 75.6 193.3 223.2 249.2 816.4 57.7 42.9 220.9 222.9 71.6 66.2 39.0 37.1 58.8 202.3 110.5 61.5 90.2 55.6 53.2 51.1 84.2 88.6 53.3 223.2 46.4 57.0 22.3 254.6 44.8 68.1 64.4 59.2 68.1 55.6 202.3 127.1 100.3 77.1 131.5 143.0 174.5 84.0 97.7 167.8 92.4 100.5 233.0 120.6 141.5 77.8 143.4 53.0 194.7 101.4 98.5 98.0 102.7 79.8 69.0 55.9 555.0 318.1 163.2 95.5 121.3 181.5 103.2 304.9 140.3 112.0 109.3 70.7 124.0 101.0 92.1 148.1 145.7 88.2 136.9 79.8 110.4 98.3 93.1 267.4 101.8 39.7 73.9 87.8 68.8 126.1 73.9 94.3 112.8 112.4 47.8 42.5 98.2 101.0 73.6 81.4 167.5 115.3 182.8 29.3 9.1 14.2 9.7 8.3 11.1 10.3 9.8 11.2 10.1 15.9 11.3 9.9 8.0 1.2 13.6 16.0 5.9 12.6 6.5 217.2 219.0 180.4 216.8 193.3 223.2 220.9 222.9 202.3 223.2 254.6 202.3 49.3 22.4 23.9 294.1 56.6 106.0 57.5 32.2 105.3 22.5 83.3 38.2 60.2 57.2 47.3 60.7 37.5 95.7 45.6 56.1 156.5 32.5 14.2 37.3 44.0 54.1 39.4 52.6 35.8 33.8 63.8 89.0 86.2 59.7 43.2 33.6 50.7 402.3 69.1 15.2 38.0 49.5 36.7 74.1 184.5 26.0 88.0 81.4 104.9 42.2 50.6 140.0 39.1 48.7 42.9 50.2 38.3 90.7 75.7 103.4 124.2 175.5 21.6 68.9 65.7 41.3 55.9 11.4 8.6 189.5 122.3 47.6 84.6 70.9 49.6 107.3 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.4" "Group enriched" "Detected in many" 4 "Astrocytes: 493.0;Excitatory neurons: 686.5;Inhibitory neurons: 866.7;Oligodendrocyte precursor cells: 576.1;Oligodendrocytes: 597.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Approved Vesicles,Cytosol NA NA 6900 "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favorable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (4.61e-5)" 13.8 11.1 35.5 3.5 36.0 2.6 13.4 48.4 54.1 9.7 20.9 11.8 7.4 9.9 11.6 12.2 11.1 6.2 17.1 36.1 37.6 25.3 62.4 9.3 3.8 32.7 35.3 8.9 23.9 11.7 13.6 3.6 32.3 11.3 10.1 23.1 9.4 6.6 24.5 15.2 9.0 6.2 32.4 6.7 14.7 6.2 34.6 5.8 11.9 13.8 4.3 11.4 10.7 39.5 39.9 8.8 13.7 15.9 14.2 17.5 9.5 11.1 5.7 12.7 12.2 2.8 17.9 0.0 1.8 7.7 5.5 13.1 17.0 19.9 18.9 15.0 14.9 15.8 9.4 22.3 7.8 9.1 15.8 13.3 13.8 2.9 16.0 4.8 11.8 13.8 9.3 14.2 7.1 19.2 11.9 22.2 5.0 28.3 17.0 0.0 32.5 13.2 16.7 7.5 25.8 10.3 10.2 31.6 12.4 3.3 18.5 11.5 6.7 14.1 24.8 11.3 13.0 22.8 9.1 0.3 10.5 0.8 11.2 0.0 0.7 0.3 2.0 1.2 3.2 1.2 2.5 1.7 1.1 1.9 1.7 1.6 0.0 1.3 1.0 1.5 3.0 0.7 35.5 36.0 48.4 54.1 36.1 37.6 32.7 35.3 32.3 32.4 34.6 39.5 11.5 6.4 13.1 493.0 11.8 4.7 9.2 5.8 27.9 34.3 12.4 6.7 12.7 8.6 10.8 1.8 52.1 3.9 3.5 8.6 13.7 4.0 3.8 7.2 13.5 10.7 6.0 7.6 686.5 5.3 2.3 8.7 19.9 13.6 0.0 3.9 15.7 47.6 3.7 43.7 866.7 15.0 8.2 5.8 1.7 5.0 11.1 4.5 1.8 148.0 1.3 8.9 1.0 576.1 597.5 3.1 7.8 5.7 15.1 11.5 7.1 20.1 2.4 34.9 0.0 12.5 11.8 11.8 8.9 26.7 5.8 2.1 7.9 9.0 10.4 6.5 GPR180 ITR ENSG00000152749 "G protein-coupled receptor 180" Q86V85 13 94601857-94634661 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047250 Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047250: AB_2679998" "unprognostic (3.91e-3)" "unprognostic (3.28e-1)" "unprognostic (4.16e-3)" "unprognostic (2.95e-1)" "unprognostic (1.17e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (6.71e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (2.49e-2)" "unprognostic (1.10e-1)" "unprognostic (8.47e-2)" "unprognostic (2.80e-2)" 5.8 2.3 3.0 2.4 3.6 0.9 2.6 4.5 4.5 2.7 4.1 2.1 2.0 2.4 1.8 1.7 2.5 1.8 1.8 3.4 3.2 2.5 6.9 2.4 2.4 2.8 3.0 2.4 3.1 2.5 3.5 3.6 3.1 2.5 2.5 7.0 2.8 2.3 1.8 1.9 1.6 2.8 3.6 2.2 2.7 1.1 3.2 2.6 3.6 1.8 2.6 2.3 1.5 3.6 14.6 3.6 5.1 5.4 10.5 11.4 2.1 9.7 7.7 9.3 12.3 4.4 9.8 4.8 4.1 8.4 6.4 9.0 7.3 6.9 12.7 12.7 4.6 9.4 4.9 0.0 8.3 13.6 7.3 6.5 5.8 5.7 7.7 8.3 9.6 6.8 2.7 2.3 9.3 2.1 6.9 3.0 3.3 10.4 4.0 7.8 6.8 2.0 10.4 4.3 7.4 5.3 4.5 9.9 12.2 6.4 7.0 5.5 8.7 5.7 4.6 6.8 8.2 3.8 4.2 2.2 9.5 10.9 7.9 0.1 0.5 0.1 0.8 0.3 1.4 0.5 0.9 0.6 0.9 0.5 1.1 0.9 0.0 0.5 0.4 0.6 1.2 0.4 3.0 3.6 4.5 4.5 3.4 3.2 2.8 3.0 3.1 3.6 3.2 3.6 9.0 3.2 4.1 20.2 6.1 6.0 5.4 11.2 7.4 12.5 7.4 5.5 6.8 7.2 7.8 12.9 31.3 8.7 9.3 3.8 5.9 8.3 1.0 11.1 8.9 8.3 10.3 3.6 47.6 10.2 27.8 11.8 9.7 9.0 5.1 9.2 9.7 30.8 10.5 18.5 30.5 9.8 6.1 4.4 4.9 0.7 9.6 5.3 7.2 18.7 4.1 15.4 9.2 40.7 26.3 9.6 3.7 5.7 16.0 10.6 3.0 7.5 16.8 22.0 6.6 6.3 10.6 3.5 10.6 6.4 4.7 4.1 6.6 3.6 5.5 5.0 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 HBE1 HBE ENSG00000213931 "Hemoglobin subunit epsilon 1" P02100 11 5268345-5505652 "Plasma proteins, Predicted intracellular proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 174.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "K-562: 10059.8" "Not detected" "Not detected" HPA043234 Approved NA NA 510000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA043234: AB_2678378" "unprognostic (7.59e-2)" "unprognostic (6.70e-2)" "unprognostic (3.76e-2)" "unprognostic (4.25e-1)" "unprognostic (1.64e-1)" "unprognostic (9.03e-2)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (7.32e-2)" "unprognostic (1.02e-3)" "unprognostic (2.14e-1)" "unprognostic (5.80e-2)" "unprognostic (7.34e-2)" 0.5 0.3 0.4 0.0 0.7 0.3 0.2 0.0 1.1 0.5 0.0 0.2 0.0 0.3 0.4 0.1 0.4 0.0 0.3 0.5 0.8 0.3 1.3 0.3 0.0 0.7 0.2 0.6 0.2 0.0 0.3 0.8 0.5 0.4 0.0 0.2 0.1 0.1 0.4 0.2 0.2 0.2 0.0 0.4 0.2 0.5 0.4 0.2 0.3 0.0 0.0 0.2 0.3 1.1 1.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 649.4 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10059.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.4 0.7 0.7 0.0 0.0 31.9 0.1 0.9 19.4 0.1 0.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.7 0.0 1.1 0.5 0.8 0.7 0.2 0.5 0.0 0.4 1.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.9 0.0 0.3 4.3 0.0 16.0 0.5 0.0 31.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 174.7 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.3 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.6 0.2 0.0 0.0 14.8 0.1 0.0 0.9 0.1 HEPN1 ENSG00000221932 "Hepatocellular carcinoma, down-regulated 1" Q6WQI6 11 124919244-124920677 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 11.4;brain: 37.3;liver: 20.9" "Group enriched" "Detected in some" 23 "Astrocytes: 94.3;Muller glia cells: 29.1;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 114.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 287 "Hep G2: 55.5" "HPA043768, HPA063054" Uncertain Approved "Golgi apparatus" Yes NA "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Golgi apparatus" "HPA043768: AB_2678662, HPA063054: AB_2684932" 11.4 0.2 6.1 0.1 23.1 0.0 8.3 0.3 9.4 0.4 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.6 5.0 6.1 0.2 20.9 0.1 0.1 37.3 10.3 0.1 0.2 0.0 2.4 0.0 13.5 0.8 0.0 2.2 0.4 0.0 0.2 0.3 0.7 0.0 5.1 0.1 0.5 0.5 19.0 0.0 0.2 0.0 0.0 0.2 0.5 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 23.1 0.3 9.4 5.0 6.1 37.3 10.3 13.5 5.1 19.0 17.9 0.2 0.0 0.0 94.3 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 3.1 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.5 0.6 0.0 0.0 1.9 0.0 29.1 0.0 49.3 114.6 0.0 0.0 1.2 0.0 0.1 0.0 2.2 0.0 1.9 0.0 0.1 0.1 1.8 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 HS1BP3 HS1-BP3,FLJ14249 ENSG00000118960 "HCLS1 binding protein 3" Q53T59 2 20560448-20651130 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035050 Approved Approved Nucleoli,Cytosol No No 54000 "Cluster 18: Basophils - Vesicular transport" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoli Cytosol "HPA035050: AB_10601816" "unprognostic (4.52e-2)" "unprognostic (5.93e-2)" "unprognostic (2.67e-1)" "unprognostic (4.39e-1)" "unprognostic (4.61e-2)" "unprognostic (1.45e-3)" "prognostic unfavorable (2.97e-5)" "unprognostic (2.06e-3)" "unprognostic (1.88e-2)" "unprognostic (2.16e-1)" "unprognostic (9.53e-2)" "unprognostic (8.00e-2)" "prognostic favorable (2.30e-4)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-1)" 18.5 31.0 16.4 10.0 20.6 13.7 15.9 17.9 19.6 21.5 19.4 33.6 13.1 22.2 13.3 18.6 19.4 16.4 23.3 16.9 17.5 24.8 57.4 18.5 9.2 20.4 19.3 17.5 14.5 13.1 16.3 15.5 19.4 26.7 12.6 3.7 16.7 17.5 13.0 23.3 17.7 21.1 15.8 18.4 22.0 13.8 21.3 7.4 17.8 10.1 7.6 29.2 17.8 23.3 20.3 23.1 11.5 14.1 58.8 39.2 22.7 7.6 34.9 17.7 23.0 18.2 24.0 13.5 5.9 11.1 80.1 12.5 23.1 24.0 8.6 17.4 19.1 7.2 11.3 61.2 54.8 5.5 30.5 42.1 53.8 20.0 36.5 20.7 34.1 11.9 4.7 28.3 20.5 17.4 2.5 9.3 9.6 29.9 16.4 13.3 23.3 13.4 39.0 24.4 10.9 16.7 5.4 23.4 45.0 23.2 14.6 11.2 21.7 17.3 18.5 27.0 11.7 19.9 24.5 12.9 37.3 25.8 18.7 17.9 14.7 14.5 6.0 13.9 4.2 6.8 3.6 4.7 9.9 4.3 3.0 3.3 17.7 3.8 18.3 3.6 3.4 8.6 16.4 20.6 17.9 19.6 16.9 17.5 20.4 19.3 19.4 15.8 21.3 23.3 17.6 6.4 17.9 3.3 8.2 4.5 7.4 5.6 2.2 4.0 6.2 8.0 6.2 8.6 10.9 7.3 0.0 9.8 6.5 12.5 17.6 21.4 20.8 9.3 9.4 8.4 6.7 7.0 2.6 14.9 17.8 9.7 8.2 12.5 2.5 8.5 11.0 9.2 30.7 15.2 2.5 7.3 12.2 20.1 5.5 42.7 8.4 13.9 14.2 4.7 13.1 8.9 15.5 3.0 5.4 9.7 11.9 10.5 4.9 5.2 21.6 28.2 10.4 5.3 0.0 7.1 17.1 16.7 10.5 5.8 5.3 17.5 6.3 7.8 7.7 4.5 ITPR2 "CFAP48, IP3R2" ENSG00000123104 "Inositol 1,4,5-trisphosphate receptor type 2" Q14571 12 26335352-26833194 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 551.4;Excitatory neurons: 287.2;Microglial cells: 802.9;Oligodendrocyte precursor cells: 441.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059144, HPA062260" Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" Nucleoplasm "HPA059144: AB_2683925, HPA062260: AB_2684728" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.37e-2)" "unprognostic (3.59e-3)" "unprognostic (8.70e-2)" "unprognostic (1.66e-1)" "unprognostic (8.61e-2)" "unprognostic (2.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.82e-1)" "unprognostic (9.13e-2)" "unprognostic (3.99e-2)" "unprognostic (3.76e-1)" 8.3 10.4 10.5 8.1 7.3 6.0 17.3 6.3 9.7 4.8 3.4 6.2 5.3 5.2 5.7 7.4 5.5 5.5 3.7 7.7 8.7 12.6 44.3 5.6 7.9 19.1 13.2 5.9 7.7 11.4 2.2 10.9 14.9 5.5 6.6 8.8 16.9 2.9 1.8 10.2 4.9 4.5 13.1 6.7 5.2 2.5 16.1 20.1 4.3 4.1 6.8 4.9 4.7 15.6 4.9 2.0 2.9 4.6 8.5 8.6 3.0 4.4 6.1 3.0 3.1 0.2 2.4 16.5 2.7 5.9 3.3 5.2 15.1 9.3 4.0 3.9 5.1 13.5 4.4 27.1 7.9 12.0 5.8 8.1 1.2 6.3 11.6 6.2 28.5 6.5 6.4 5.1 3.9 4.0 8.6 17.8 12.2 4.4 1.5 2.9 7.0 10.7 7.3 7.4 0.9 4.5 19.8 3.5 11.4 11.3 7.7 6.0 62.6 6.0 2.3 5.9 5.7 4.9 4.2 31.2 5.7 5.6 3.9 32.4 6.4 9.9 2.9 2.7 2.5 5.4 2.6 2.4 1.4 5.0 3.0 2.7 17.3 4.8 4.3 11.9 4.4 1.0 10.5 7.3 6.3 9.7 7.7 8.7 19.1 13.2 14.9 13.1 16.1 15.6 27.1 48.1 52.9 551.4 45.7 20.9 17.8 3.3 31.3 3.2 87.0 57.1 24.5 34.3 8.6 23.9 146.0 21.0 39.1 7.7 7.9 20.8 3.1 13.3 64.9 38.5 78.5 33.4 287.2 23.4 9.5 20.3 16.8 22.7 44.4 60.0 25.0 123.7 39.5 0.0 99.1 46.1 32.6 46.3 8.2 6.7 18.0 68.7 33.8 802.9 28.2 13.0 41.2 441.8 22.3 17.6 37.0 17.7 83.6 25.9 14.5 14.6 5.0 64.7 0.0 22.7 17.6 3.6 6.3 54.3 26.7 27.9 29.2 43.4 11.7 15.8 KANK1 "ANKRD15, KANK, KIAA0172" ENSG00000107104 "KN motif and ankyrin repeat domains 1" Q14678 9 470291-746106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 355.5;Late spermatids: 228.7;Oligodendrocyte precursor cells: 322.7;Oligodendrocytes: 191.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.0" "Group enriched" "Detected in many" 15 "B-cells: 1.1;dendritic cells: 4.0;T-cells: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005539, HPA056090" Approved Supported "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA005539: AB_1078164, HPA056090: AB_2683034" "unprognostic (6.59e-2)" "unprognostic (3.33e-2)" "unprognostic (1.06e-3)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" "unprognostic (7.53e-2)" "unprognostic (3.33e-1)" "unprognostic (1.23e-2)" "unprognostic (4.91e-2)" "unprognostic (3.05e-2)" "unprognostic (2.84e-2)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.72e-1)" "unprognostic (3.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" 42.6 9.6 49.0 9.5 52.7 1.5 31.2 42.3 47.5 40.9 61.8 49.2 12.1 62.2 13.0 64.6 31.7 15.2 88.2 45.1 44.9 31.6 101.9 13.6 7.6 51.6 44.9 22.1 28.3 9.4 27.9 25.8 48.3 42.5 14.9 11.0 29.9 31.8 66.4 51.8 23.6 37.4 47.6 6.9 25.9 15.4 48.4 9.4 30.8 39.9 11.8 70.1 52.3 48.9 5.9 12.2 4.0 72.0 57.8 21.9 19.9 37.1 25.8 3.1 3.7 30.2 2.5 46.2 8.9 46.0 7.0 12.3 15.7 30.4 5.3 22.7 8.3 0.1 17.0 96.0 8.1 11.2 0.0 12.6 41.6 3.2 35.6 13.2 31.2 1.6 2.4 56.4 23.1 14.4 4.5 46.9 5.3 8.9 9.0 1.7 7.9 8.6 24.5 36.1 1.8 0.0 3.6 10.9 50.9 33.3 7.1 8.7 46.1 8.4 3.2 10.8 17.1 9.8 61.9 0.2 5.6 21.1 15.8 0.0 0.1 0.0 0.1 0.1 0.0 0.8 1.3 0.4 0.4 1.1 2.4 0.8 0.0 0.1 0.0 4.0 1.7 0.5 49.0 52.7 42.3 47.5 45.1 44.9 51.6 44.9 48.3 47.6 48.4 48.9 18.3 12.8 34.2 355.5 4.9 23.1 102.1 11.4 37.0 22.2 16.8 18.0 94.1 24.3 8.1 18.4 41.7 89.2 15.7 8.3 7.9 11.6 102.3 14.2 15.4 21.9 18.0 9.1 12.1 7.9 6.8 21.8 7.7 13.1 1.3 38.5 23.6 70.0 13.3 0.0 29.0 12.8 4.1 6.9 6.5 228.7 32.3 3.3 23.2 60.9 1.2 6.5 0.0 322.7 191.4 9.6 7.5 20.7 10.7 50.5 17.6 13.6 7.0 20.2 26.3 129.9 24.0 28.4 25.6 36.2 25.7 66.2 4.7 6.9 26.0 63.6 KCND3 "KSHIVB, Kv4.3, SCA19, SCA22" ENSG00000171385 "Potassium voltage-gated channel subfamily D member 3" Q9UK17 1 111770662-111989668 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 46.8;Cardiomyocytes: 38.1;Excitatory neurons: 105.7;Hepatocytes: 37.8;Inhibitory neurons: 88.4;Oligodendrocyte precursor cells: 45.8" "Cancer enhanced" "Detected in many" "prostate cancer: 8.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 4.8;SCLC-21H: 10.1;U-2 OS: 1.6;WM-115: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029452 Approved NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA029452: AB_10602239" "unprognostic (1.11e-2)" "unprognostic (1.73e-3)" "unprognostic (1.71e-1)" "unprognostic (2.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (1.41e-1)" "unprognostic (9.48e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-2)" "unprognostic (1.40e-1)" "unprognostic (7.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-3)" "unprognostic (6.64e-3)" 4.5 1.5 17.0 4.7 13.8 0.2 3.0 18.1 17.9 2.3 0.0 5.9 0.9 5.3 12.6 4.1 5.1 5.5 8.4 16.2 6.4 1.3 15.4 1.7 0.5 1.0 35.6 0.5 4.5 3.9 3.4 0.5 3.4 11.3 2.4 12.7 1.6 12.0 2.6 7.1 2.2 9.8 0.9 3.2 3.3 2.0 9.2 0.3 1.1 1.7 0.5 5.9 3.2 10.8 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.4 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.2 10.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.0 13.8 18.1 17.9 16.2 6.4 1.0 35.6 3.4 0.9 9.2 10.8 1.1 0.0 9.3 18.3 0.3 7.5 11.9 2.9 0.0 46.8 7.8 1.5 38.1 0.0 1.5 0.0 4.2 0.1 0.4 1.5 0.0 0.8 35.7 0.5 14.5 1.6 0.0 2.7 105.7 23.8 0.2 3.7 0.0 0.7 0.0 0.0 1.8 37.8 0.2 30.3 88.4 0.4 4.1 0.8 1.9 32.3 18.0 0.5 3.6 1.0 0.0 6.2 0.0 45.8 8.7 4.8 1.2 1.9 0.0 21.9 0.1 0.3 0.1 4.8 0.0 0.8 1.7 1.5 1.0 2.0 6.7 0.0 0.5 0.1 2.4 13.4 KCNN2 "hSK2, KCa2.2" ENSG00000080709 "Potassium calcium-activated channel subfamily N member 2" Q9H2S1 5 114055926-114496500 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 27.8;brain: 20.8;liver: 31.3" "Cell type enhanced" "Detected in some" "Astrocytes: 36.2;Excitatory neurons: 149.9;Inhibitory neurons: 97.0;Oligodendrocyte precursor cells: 63.3" "Group enriched" "Detected in some" 7 "glioma: 3.5;melanoma: 3.2;prostate cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 17.5;NTERA-2: 6.4;SK-MEL-30: 12.9;THP-1: 21.8;U-937: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038221 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA038221: AB_10673044" "unprognostic (9.22e-3)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (4.61e-1)" "unprognostic (3.16e-1)" "unprognostic (4.25e-1)" 0.4 27.8 7.8 0.2 10.8 0.0 0.5 11.3 14.0 2.0 2.2 1.4 0.3 2.9 0.3 0.2 0.4 0.4 6.8 20.8 7.5 3.9 31.3 2.3 0.4 11.1 4.7 0.7 4.5 0.4 7.6 0.0 6.7 9.6 0.7 2.5 0.5 4.3 9.5 1.3 0.3 2.0 9.0 0.5 0.7 3.0 8.2 0.2 0.3 6.7 0.2 2.3 1.0 11.1 0.1 0.0 0.0 0.0 0.0 0.0 2.1 17.5 2.7 0.3 0.0 0.0 0.2 0.0 0.5 0.0 2.3 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.2 0.0 0.3 0.0 1.4 6.4 0.0 0.0 0.0 0.0 0.8 0.2 0.1 2.1 0.0 0.0 0.2 12.9 0.4 0.3 21.8 0.3 0.0 0.5 1.8 0.0 0.1 0.0 0.1 2.0 7.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 10.8 11.3 14.0 20.8 7.5 11.1 4.7 6.7 9.0 8.2 11.1 1.4 0.0 1.1 36.2 0.0 0.3 0.3 0.0 0.0 7.9 0.6 1.3 15.1 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.6 0.6 0.5 0.0 8.2 0.0 0.0 149.9 0.9 0.0 0.8 0.0 1.3 0.0 0.8 5.0 18.3 0.0 0.0 97.0 1.0 0.0 1.0 0.3 0.5 0.0 0.1 21.4 6.5 0.0 0.4 0.0 63.3 9.2 1.0 0.1 0.0 1.2 4.7 0.0 0.7 0.0 7.8 0.0 0.1 0.3 0.3 6.5 0.3 0.3 0.0 0.0 0.2 0.5 0.6 KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.2;Inhibitory neurons: 240.5;Oligodendrocyte precursor cells: 310.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;hTERT-RPE1: 9.0;SCLC-21H: 7.5;SH-SY5Y: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" 1.0 0.6 0.9 0.1 2.0 0.0 0.4 0.0 2.0 0.4 0.3 0.5 0.2 0.3 0.4 1.0 0.5 1.4 1.8 2.5 3.3 0.3 2.8 1.8 0.1 0.0 0.2 3.8 0.1 0.0 0.9 0.2 0.0 1.0 0.5 0.1 0.5 0.6 0.1 0.3 0.4 0.5 0.6 0.2 0.5 1.1 1.0 0.1 1.1 0.8 0.1 0.8 0.4 0.5 0.0 0.1 1.8 0.0 0.2 0.2 0.0 0.0 1.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.9 0.0 3.2 0.0 0.0 1.2 0.0 0.4 0.1 9.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 2.4 0.0 0.1 0.0 0.1 0.0 0.0 0.5 7.5 5.6 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 2.0 2.5 3.3 0.0 0.2 0.0 0.6 1.0 0.5 0.8 41.7 1.1 6.8 0.0 0.4 0.2 0.0 0.6 0.0 0.0 0.1 1.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.2 0.8 0.0 0.0 220.2 0.0 0.0 9.3 0.0 0.0 0.0 6.1 2.5 6.2 0.0 0.0 240.5 0.0 0.0 0.0 0.7 3.3 6.5 0.0 1.8 58.1 0.0 0.0 0.0 310.7 6.1 0.0 0.0 4.9 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.4 4.0 0.6 0.2 0.0 0.0 0.0 0.0 3.9 0.0 0.2 KCTD21 KCASH2 ENSG00000188997 "Potassium channel tetramerization domain containing 21" Q4G0X4 11 78171249-78188626 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041964 Uncertain Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041964: AB_10795647" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (3.74e-3)" "unprognostic (6.40e-3)" "unprognostic (8.06e-2)" "unprognostic (2.48e-2)" "unprognostic (1.52e-1)" "unprognostic (6.82e-2)" "unprognostic (8.85e-2)" "unprognostic (1.37e-3)" "unprognostic (2.49e-1)" "unprognostic (1.31e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "unprognostic (4.70e-1)" "prognostic favorable (9.57e-5)" "unprognostic (3.43e-2)" 7.3 13.4 14.4 6.2 13.6 3.5 4.4 13.1 14.3 5.8 8.7 6.5 5.0 5.0 9.2 9.6 6.2 7.9 6.3 13.7 14.3 5.5 15.9 6.7 5.4 14.7 16.3 13.7 3.5 5.7 5.9 7.7 15.0 4.2 4.8 4.3 5.8 5.2 8.5 4.9 4.5 7.1 12.4 4.6 4.5 4.0 14.6 5.9 11.2 7.0 6.2 7.1 5.9 14.7 5.2 11.8 6.7 5.0 23.8 16.9 4.1 10.1 9.6 7.1 7.1 11.1 7.8 5.0 9.9 11.4 9.5 10.1 6.5 8.4 7.3 6.9 3.9 3.8 15.4 9.8 13.2 2.4 4.7 16.4 15.4 15.5 8.8 14.8 11.0 6.1 8.1 4.5 9.7 7.3 3.8 7.3 3.0 19.0 8.9 5.0 5.1 3.1 8.3 9.3 4.6 7.1 6.4 4.6 4.9 12.1 10.6 2.6 12.9 11.3 11.0 30.0 3.9 8.6 9.2 4.8 5.9 3.9 6.4 2.0 5.4 7.5 0.9 6.0 1.4 0.6 1.4 1.7 3.7 1.4 1.3 1.0 8.3 1.4 5.1 0.8 1.1 2.2 14.4 13.6 13.1 14.3 13.7 14.3 14.7 16.3 15.0 12.4 14.6 14.7 1.9 0.0 2.7 4.6 0.7 1.8 1.2 1.5 0.6 1.7 2.4 2.2 3.5 5.7 2.0 0.0 0.0 1.2 0.6 2.8 1.9 1.5 0.3 1.4 2.5 2.3 0.0 0.0 4.1 2.2 1.1 2.8 1.1 1.9 5.7 7.0 3.6 7.4 2.3 6.7 3.4 1.3 0.0 3.1 1.1 0.5 4.4 1.3 1.8 4.7 2.8 1.0 0.0 4.0 4.2 2.5 1.7 9.1 1.0 1.9 2.3 2.7 1.1 0.9 0.0 1.2 2.9 1.5 2.7 3.6 1.4 1.9 1.8 3.8 1.7 2.1 KLHL25 "ENC-2, ENC2, FLJ12587" ENSG00000183655 "Kelch like family member 25" Q9H0H3 15 85759326-85794925 "Predicted intracellular proteins" "Translation regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 3.8" "Group enriched" "Detected in many" 4 "monocytes: 3.8;NK-cells: 2.5;T-cells: 1.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 29.1;hippocampal formation: 16.3" HPA023450 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA023450: AB_1852583" "unprognostic (1.18e-1)" "unprognostic (1.06e-2)" "unprognostic (2.78e-2)" "unprognostic (1.99e-2)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (8.98e-2)" "unprognostic (6.60e-2)" "unprognostic (9.29e-3)" "unprognostic (4.25e-2)" "unprognostic (5.18e-2)" "unprognostic (2.22e-2)" "unprognostic (3.57e-2)" "unprognostic (1.80e-1)" "unprognostic (2.08e-1)" "unprognostic (2.66e-2)" 6.5 2.4 5.6 2.6 7.6 0.5 5.4 5.8 7.5 4.3 4.3 3.8 4.7 6.6 3.1 5.7 4.0 2.2 3.9 6.0 7.6 3.7 15.1 4.3 1.9 5.4 8.2 3.3 1.6 2.2 3.6 1.1 6.9 4.6 1.1 0.8 3.6 3.1 6.5 9.3 3.4 2.8 4.7 1.6 5.0 10.5 7.6 2.0 2.4 3.0 1.3 3.7 5.0 6.7 2.7 8.1 11.6 5.7 2.3 1.2 6.0 3.4 1.6 4.6 3.5 10.9 4.4 1.7 1.7 2.8 2.9 6.6 12.5 6.4 1.0 1.7 5.8 0.5 3.5 8.4 2.7 0.5 2.0 2.4 2.1 4.5 1.5 2.0 2.5 5.8 0.7 1.5 2.0 5.0 4.3 2.6 10.5 4.6 4.2 8.7 6.9 2.8 1.7 5.6 16.1 11.1 4.9 5.6 2.2 4.7 10.2 0.6 2.1 4.9 8.9 3.2 6.2 1.6 3.7 1.7 2.2 3.0 2.8 0.0 0.1 0.2 1.0 1.2 0.5 0.0 1.0 0.7 0.2 0.2 1.7 1.1 0.0 2.5 3.8 0.6 0.9 0.5 5.6 7.6 5.8 7.5 6.0 7.6 5.4 8.2 6.9 4.7 7.6 6.7 0.8 0.0 1.9 3.6 1.2 2.7 4.0 2.1 0.0 3.3 4.0 2.8 4.3 1.5 1.5 0.0 0.0 1.0 3.6 6.3 1.9 2.3 13.0 3.0 3.6 1.8 10.7 0.0 7.7 2.7 1.5 2.4 8.6 3.2 0.0 2.0 2.2 12.4 0.8 13.5 4.1 7.6 4.1 1.3 2.7 4.6 0.9 1.4 7.2 1.0 0.6 2.7 2.1 6.0 0.9 5.3 3.1 1.5 1.3 2.7 2.7 2.1 2.1 1.1 6.6 2.9 2.9 3.3 4.1 4.4 4.7 1.8 4.0 1.4 5.2 4.3 KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 186.3;Microglial cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 323.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" 41.4 22.4 53.9 32.3 53.8 9.0 18.7 44.8 56.5 17.0 29.4 44.4 12.7 19.1 13.5 32.0 9.4 23.1 14.4 49.8 50.0 25.0 42.3 20.2 33.7 53.5 50.2 18.4 11.3 12.9 7.5 28.0 53.0 35.9 16.1 11.8 10.2 66.0 10.7 6.1 13.2 46.1 56.7 21.0 13.1 11.0 55.2 14.6 21.5 18.9 38.9 34.8 9.5 52.6 56.7 78.2 40.9 30.2 22.9 58.5 59.1 44.2 323.1 36.6 35.4 64.6 40.4 86.4 52.4 45.5 192.7 3.3 50.7 112.3 46.6 8.8 10.1 36.8 71.4 46.5 195.6 10.9 11.9 74.5 61.9 55.5 137.7 134.1 73.7 13.8 28.2 17.0 87.1 23.8 11.5 19.6 12.6 14.3 75.5 20.9 53.7 2.1 31.3 23.0 2.8 29.7 25.0 8.0 21.8 49.0 19.3 22.9 94.2 96.8 65.4 25.5 53.8 19.3 18.7 79.0 78.6 28.3 22.9 5.4 2.2 0.4 0.7 3.2 1.1 5.1 1.4 0.8 2.5 3.7 1.1 0.5 2.3 1.0 1.4 0.9 0.2 0.8 53.9 53.8 44.8 56.5 49.8 50.0 53.5 50.2 53.0 56.7 55.2 52.6 74.9 16.0 1.1 45.7 38.0 3.7 9.4 22.9 7.4 18.8 16.5 11.2 4.5 17.2 33.7 11.0 4.2 1.0 6.3 0.3 17.6 39.3 2.8 4.0 11.1 43.6 1.2 10.9 46.1 21.0 57.9 12.6 3.1 5.3 2.5 9.5 22.9 35.6 13.3 70.7 186.3 0.4 12.2 25.4 25.8 6.6 8.1 28.6 17.8 190.2 27.5 12.1 7.2 69.9 79.0 24.3 0.1 13.9 43.0 31.5 2.0 21.8 32.7 3.4 0.0 14.2 17.3 9.8 5.6 3.3 3.4 5.7 10.7 32.4 0.7 14.1 LCAT ENSG00000213398 "Lecithin-cholesterol acyltransferase" P04180 16 67939750-67944131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Hydrolase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 283.0" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 219.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 76.5;Hep G2: 62.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 29.2" HPA044767 Approved Nucleoplasm "Secreted to blood" NA NA 6470000000 6400000000 "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA044767: AB_2756312" "unprognostic (3.34e-2)" "unprognostic (3.56e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.43e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-1)" "prognostic favorable (4.21e-8)" "unprognostic (6.42e-2)" "unprognostic (4.26e-1)" "unprognostic (4.12e-1)" "unprognostic (1.50e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (9.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.90e-3)" 29.5 20.8 29.3 8.3 29.8 4.2 27.2 56.7 37.5 41.4 37.8 30.6 5.0 28.7 9.1 13.4 26.1 11.5 42.0 28.5 32.3 33.2 283.0 36.1 7.5 41.9 32.7 28.5 17.7 8.0 17.5 17.8 31.6 40.0 4.8 2.8 16.9 18.6 13.2 32.0 17.8 12.3 31.9 23.3 16.5 11.3 33.4 9.4 43.2 8.9 4.4 27.5 27.3 32.0 5.7 9.0 13.0 14.8 11.1 15.6 76.5 21.9 9.3 14.5 10.2 29.5 6.8 3.1 4.0 31.9 5.3 19.4 3.1 30.0 8.9 1.5 7.9 3.9 22.8 62.9 15.2 0.7 10.3 27.1 27.9 30.0 10.4 19.5 10.8 8.7 8.7 1.2 10.5 9.1 3.7 9.5 8.6 1.1 5.0 4.0 14.1 3.3 4.1 9.6 0.5 6.7 33.1 1.6 3.9 26.5 18.6 6.0 20.6 18.5 28.8 20.7 8.1 17.7 5.2 8.3 8.9 2.5 16.5 0.9 0.4 1.9 0.3 0.0 0.4 0.4 0.2 0.3 0.1 0.6 0.4 0.1 1.0 0.4 0.1 0.3 0.0 0.0 29.3 29.8 56.7 37.5 28.5 32.3 41.9 32.7 31.6 31.9 33.4 32.0 16.5 9.6 4.8 27.4 1.1 9.4 4.1 4.6 6.8 0.4 1.9 5.5 7.9 5.7 3.3 3.7 2.1 7.7 1.3 0.1 0.0 1.7 0.2 2.1 6.0 8.0 1.2 14.3 0.1 1.0 3.4 7.3 1.1 1.6 1.3 5.4 10.8 219.5 2.4 0.0 0.1 0.0 4.1 6.6 3.8 1.3 8.7 2.4 7.2 6.5 3.0 7.7 1.0 4.5 1.4 2.1 0.0 8.6 1.9 4.3 0.0 0.4 4.4 0.6 13.1 7.6 10.4 0.9 1.4 0.9 2.6 12.2 1.6 4.1 0.1 1.7 LMAN2L "DKFZp564L2423, VIPL" ENSG00000114988 "Lectin, mannose binding 2 like" Q9H0V9 2 96705929-96740064 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026600 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA026600: AB_1852939" "unprognostic (3.02e-1)" "unprognostic (2.34e-1)" "unprognostic (2.17e-3)" "unprognostic (1.83e-2)" "unprognostic (2.19e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-2)" "unprognostic (4.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.80e-1)" "unprognostic (6.91e-3)" "unprognostic (1.16e-1)" "unprognostic (5.30e-2)" "unprognostic (8.14e-2)" "unprognostic (2.17e-1)" "unprognostic (1.52e-1)" "unprognostic (3.29e-1)" 10.1 11.0 16.5 4.9 17.4 1.3 12.2 16.6 20.0 15.8 15.9 14.4 5.6 13.8 17.2 9.5 17.1 6.7 19.2 16.6 21.9 17.9 18.1 9.8 5.9 18.1 17.7 21.1 11.9 13.7 17.3 11.6 17.9 15.0 10.6 7.7 10.9 13.6 16.7 11.0 8.2 15.6 16.7 8.6 10.8 11.2 22.9 9.1 15.5 19.1 7.1 13.2 12.5 17.2 21.1 33.3 25.6 26.6 31.9 15.1 23.4 19.3 23.9 39.9 43.5 57.4 15.7 10.2 71.4 47.8 99.2 25.1 36.9 30.2 50.2 27.1 20.4 8.9 21.4 49.0 20.1 15.3 14.3 17.4 28.2 30.5 9.6 34.7 23.7 17.2 20.3 20.5 25.5 14.5 11.0 14.5 13.9 14.9 36.0 23.1 21.1 11.6 32.9 10.9 16.2 8.5 21.8 16.6 20.1 46.8 19.8 26.4 17.3 31.8 22.7 25.1 25.9 13.3 46.1 8.6 18.8 18.1 26.3 37.8 17.5 22.4 14.0 10.6 32.0 20.0 16.2 18.9 14.5 16.9 19.6 16.6 9.5 15.9 16.0 20.8 14.8 18.5 16.5 17.4 16.6 20.0 16.6 21.9 18.1 17.7 17.9 16.7 22.9 17.2 4.7 12.8 6.8 12.4 3.2 3.4 5.4 11.1 2.2 3.1 10.5 7.6 12.2 5.7 6.3 12.9 6.2 17.9 5.2 5.4 9.8 13.7 20.6 4.6 6.9 6.1 9.5 6.5 13.4 7.8 10.4 11.8 2.0 5.6 5.1 16.8 9.3 10.7 9.9 1.7 13.4 5.0 0.0 5.6 1.4 18.0 6.8 2.7 3.6 7.5 12.3 12.2 6.2 11.1 11.0 7.5 3.8 8.6 3.1 4.5 4.6 10.1 6.3 5.1 13.1 4.4 8.1 13.3 14.0 2.5 2.7 13.4 4.0 8.6 6.5 2.1 LSS OSC ENSG00000160285 "Lanosterol synthase" P48449 21 46188141-46228824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Isomerase "Cataract, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 132.0;Oligodendrocytes: 158.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 234.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032060, HPA032062, CAB034116" Supported NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB034116: AB_2138611, HPA032060: AB_10671085, HPA032062: AB_2674134" "unprognostic (2.78e-3)" "unprognostic (8.53e-3)" "unprognostic (6.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.92e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.07e-4)" 29.3 38.9 20.0 10.8 30.8 5.7 22.3 38.9 33.5 20.8 7.1 22.9 28.5 26.6 12.1 39.7 18.0 9.0 25.1 15.7 26.2 10.7 54.8 24.1 9.4 62.3 40.7 30.3 19.4 12.2 25.9 8.0 65.7 24.0 10.7 6.8 16.1 12.4 29.0 27.6 17.4 12.2 28.4 7.6 23.3 17.5 40.4 12.3 10.2 19.5 8.0 20.2 19.6 58.7 70.4 22.2 70.9 30.6 94.1 90.6 20.3 26.8 186.4 32.1 62.7 73.9 54.4 15.4 22.3 51.7 234.6 32.7 63.2 110.9 12.9 14.9 34.5 37.7 38.6 48.3 85.5 13.7 25.1 89.0 41.4 59.7 25.6 22.2 26.9 72.1 37.4 87.3 27.8 23.8 29.9 19.7 115.4 11.3 20.1 34.9 21.9 92.2 82.8 38.1 41.4 36.7 31.4 24.0 27.5 30.6 38.0 33.7 40.8 37.9 30.2 33.8 21.1 31.8 29.5 30.6 39.7 59.4 16.6 4.6 2.1 2.2 4.0 1.8 2.8 3.1 2.9 4.9 2.4 1.5 2.4 3.6 0.0 1.7 1.5 5.0 1.4 3.6 20.0 30.8 38.9 33.5 15.7 26.2 62.3 40.7 65.7 28.4 40.4 58.7 13.8 12.8 36.8 66.6 7.2 37.0 3.8 30.2 8.0 16.0 15.3 8.0 13.7 14.3 18.7 11.0 4.2 3.7 11.8 10.4 0.0 10.5 6.5 6.6 16.4 10.3 19.7 16.8 21.2 17.2 6.7 19.7 13.3 14.6 3.8 20.6 11.4 132.0 9.7 23.5 24.2 11.6 16.2 7.5 13.7 6.6 21.1 4.9 21.4 21.5 12.0 7.5 5.2 22.1 158.8 14.0 2.7 13.5 6.3 16.2 5.0 4.1 11.0 16.4 0.0 9.8 8.5 20.3 18.1 12.6 54.0 6.3 7.9 18.0 10.9 4.6 MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 317.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 120.6;granulocytes: 137.8;Hepatocytes: 221.1;Peritubular cells: 95.2;Proximal enterocytes: 178.8;Proximal tubular cells: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 41.4;SiHa: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 110000 "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" 78.0 51.1 99.3 6.5 102.8 0.1 45.7 89.1 117.7 32.3 83.5 46.5 73.5 119.4 55.0 31.4 98.0 17.3 97.8 93.9 149.1 124.2 317.6 33.0 6.1 143.8 134.2 155.4 10.9 15.6 25.9 11.2 125.9 82.9 16.5 13.9 78.5 155.5 114.6 9.9 79.0 103.3 115.8 2.4 23.7 9.0 145.2 3.8 5.6 65.1 7.1 28.3 25.4 115.8 0.0 1.0 0.1 0.0 0.6 0.1 0.3 0.0 0.0 0.0 0.0 5.4 4.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 8.1 41.4 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.3 3.5 0.0 0.0 0.0 0.0 0.4 4.0 0.0 0.1 1.1 78.2 0.0 0.5 0.6 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 99.3 102.8 89.1 117.7 93.9 149.1 143.8 134.2 125.9 115.8 145.2 115.8 5.9 0.0 4.1 53.5 0.4 5.5 0.4 1.2 1.8 1.4 3.5 22.4 120.6 52.9 1.9 5.5 4.2 0.4 0.0 10.2 62.6 20.1 0.4 26.4 81.6 10.3 0.0 2.7 36.9 2.8 0.5 17.0 16.3 6.0 137.8 69.6 7.5 221.1 1.5 15.2 7.6 6.4 12.2 4.3 3.6 2.1 46.0 1.8 7.2 9.4 0.0 27.2 0.0 11.6 1.3 7.9 7.8 95.2 0.3 0.6 178.8 182.6 11.8 1.0 13.1 2.6 18.4 0.3 0.4 2.3 4.0 0.4 5.5 0.5 10.5 0.5 MBNL2 "MBLL, MBLL39" ENSG00000139793 "Muscleblind like splicing regulator 2" Q5VZF2 13 97221434-97394120 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 325.5;Oligodendrocytes: 702.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062685 Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA062685: AB_2684834" "unprognostic (8.02e-2)" "unprognostic (7.78e-2)" "unprognostic (6.37e-2)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.58e-1)" "unprognostic (3.54e-1)" "unprognostic (1.44e-3)" "unprognostic (1.08e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.00e-1)" "unprognostic (5.26e-3)" "unprognostic (1.01e-2)" "unprognostic (1.48e-1)" "unprognostic (2.73e-1)" "unprognostic (9.17e-2)" 64.4 64.6 34.6 20.7 52.0 8.5 35.1 51.4 58.5 38.7 18.3 31.8 21.1 35.0 16.0 38.2 21.7 44.8 36.8 32.9 38.6 36.9 94.9 29.6 20.8 47.5 46.6 59.3 46.4 25.8 23.8 52.6 49.0 31.9 24.5 50.1 41.4 38.4 41.6 18.9 19.1 41.5 45.2 19.8 30.5 14.4 42.2 24.2 36.6 87.9 24.2 34.9 24.5 80.6 34.7 12.1 13.5 13.7 68.9 36.1 1.3 77.8 38.4 34.8 35.3 14.8 49.8 11.7 31.4 106.3 39.5 48.6 6.1 34.1 44.6 31.2 5.9 14.2 26.4 34.7 101.7 1.6 12.4 37.9 56.7 28.6 54.7 39.5 67.4 15.5 18.1 6.0 17.6 9.2 8.2 4.9 0.4 4.2 20.2 3.8 27.9 9.8 46.2 41.1 17.3 28.7 45.0 44.6 76.2 30.3 18.9 2.0 21.1 5.2 16.1 9.7 16.2 16.0 4.3 3.1 33.1 4.0 93.2 15.0 5.4 8.0 8.1 7.1 10.3 7.6 7.3 7.4 5.7 6.2 6.3 8.6 0.8 4.9 5.4 4.7 8.3 6.2 34.6 52.0 51.4 58.5 32.9 38.6 47.5 46.6 49.0 45.2 42.2 80.6 153.8 83.3 45.1 148.9 52.3 70.2 27.4 15.7 129.1 23.7 50.7 49.9 69.8 50.1 40.1 29.5 47.9 25.3 31.6 22.6 19.6 26.6 3.1 59.1 113.8 66.6 48.6 24.8 325.5 42.7 78.0 75.7 83.6 50.0 17.7 40.5 45.3 78.8 14.4 47.1 108.3 29.0 8.2 32.1 30.6 9.1 70.5 31.2 56.9 144.3 19.5 84.8 18.6 144.3 702.4 54.0 14.5 44.8 169.1 22.3 16.3 40.1 54.5 112.6 46.0 29.9 80.8 1.1 1.0 54.2 48.6 25.0 40.8 28.2 17.9 30.3 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MOCS1 MOCOD ENSG00000124615 "Molybdenum cofactor synthesis 1" Q9NZB8 6 39899578-39934551 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.7;Hepatocytes: 36.2;Sertoli cells: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.4;JURKAT: 51.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045783, HPA058177, HPA075505" Uncertain Enhanced Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA045783: AB_10960058, HPA058177: AB_2683629, HPA075505: AB_2686751" "unprognostic (1.22e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (3.26e-2)" "unprognostic (1.44e-1)" "unprognostic (9.03e-2)" "unprognostic (1.99e-1)" "unprognostic (2.61e-2)" "unprognostic (4.85e-2)" "unprognostic (3.14e-2)" "unprognostic (1.08e-1)" "prognostic favorable (6.07e-5)" "unprognostic (5.34e-3)" "unprognostic (1.21e-1)" "unprognostic (3.97e-3)" "unprognostic (2.78e-1)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" 33.7 9.5 14.6 3.2 17.9 0.0 26.8 16.8 14.7 8.8 11.2 11.7 16.2 10.0 10.1 6.7 10.3 5.5 22.0 12.7 16.0 20.4 40.3 22.9 4.5 17.4 18.8 9.0 11.9 9.6 5.3 35.6 16.2 5.3 5.6 3.0 6.1 7.5 25.7 7.3 12.7 9.2 15.6 2.6 7.6 3.2 17.3 3.3 16.0 45.0 3.4 10.0 6.6 16.4 0.0 2.1 7.0 11.4 19.3 7.2 15.2 8.7 15.0 12.1 10.0 40.4 0.1 0.0 8.4 7.4 7.0 0.4 8.2 9.8 8.7 0.0 8.6 0.0 0.0 13.7 12.2 0.0 3.1 12.0 3.7 7.9 4.2 7.2 10.1 51.1 8.4 0.7 11.7 5.0 16.0 0.0 7.9 0.1 4.6 0.0 6.3 1.1 7.6 8.2 6.1 8.5 0.0 4.2 7.0 6.3 5.2 1.4 16.2 12.2 9.8 7.7 4.1 0.0 1.7 0.0 1.3 0.0 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.5 0.0 0.3 0.0 0.0 0.0 0.2 14.6 17.9 16.8 14.7 12.7 16.0 17.4 18.8 16.2 15.6 17.3 16.4 5.7 6.4 1.5 6.2 0.1 0.6 0.6 0.7 1.2 1.6 9.3 6.5 11.6 8.6 0.3 9.2 12.5 33.7 0.5 3.6 5.9 4.4 0.8 0.9 1.6 3.3 0.0 0.0 3.2 4.1 2.3 4.3 1.1 1.4 1.3 6.3 3.3 36.2 2.9 3.3 2.6 3.5 0.0 2.8 1.0 1.8 3.7 0.4 1.8 2.8 0.0 4.6 0.0 1.0 4.4 1.0 9.1 3.0 1.3 0.2 13.2 17.8 0.0 2.2 78.9 3.9 20.3 1.6 1.9 1.2 1.1 6.2 0.3 0.8 5.5 0.6 MPDZ MUPP1 ENSG00000107186 "Multiple PDZ domain crumbs cell polarity complex component" O75970 9 13105706-13279692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 85.7" "Cell type enhanced" "Detected in many" "Astrocytes: 121.5;Excitatory neurons: 213.6;Inhibitory neurons: 271.3;Oligodendrocyte precursor cells: 158.8;Oligodendrocytes: 279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 58.1;HUVEC TERT2: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013512, HPA020255, HPA026686" Enhanced NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB013512: AB_2533517, HPA020255: AB_1854073, HPA026686: AB_1854074" "unprognostic (1.55e-1)" "unprognostic (4.21e-3)" "unprognostic (4.09e-3)" "unprognostic (1.68e-1)" "unprognostic (4.28e-2)" "unprognostic (1.03e-1)" "prognostic favorable (8.68e-4)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.50e-1)" "prognostic favorable (7.40e-4)" "unprognostic (1.54e-1)" "unprognostic (2.59e-3)" "unprognostic (1.32e-3)" "unprognostic (2.50e-1)" "unprognostic (1.58e-1)" "unprognostic (9.74e-2)" 22.7 9.9 18.0 5.3 23.2 0.2 13.2 20.3 20.6 14.3 21.7 16.1 2.8 17.8 15.3 7.6 17.5 11.7 29.8 18.0 20.4 18.8 85.7 11.1 3.9 19.8 22.4 25.6 4.6 11.3 10.7 24.7 20.3 19.2 5.3 33.0 6.3 23.2 19.9 3.8 6.4 18.6 21.4 11.1 7.6 11.5 17.7 4.3 11.7 31.3 1.8 12.6 9.9 35.3 16.1 21.2 58.1 26.0 39.2 35.4 11.8 15.9 16.4 13.8 13.1 0.0 0.0 0.0 4.5 39.6 14.2 0.3 17.3 8.8 22.3 0.0 10.2 10.5 21.9 3.9 20.8 0.1 5.4 26.5 3.6 9.7 6.6 35.3 53.5 0.0 0.3 0.1 12.5 4.2 0.0 0.2 24.9 0.0 9.0 0.0 14.2 0.0 13.7 8.5 7.2 26.9 12.6 2.8 15.5 39.7 8.1 0.1 42.8 14.1 2.7 4.7 12.4 0.0 0.0 0.0 6.8 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 23.2 20.3 20.6 18.0 20.4 19.8 22.4 20.3 21.4 17.7 35.3 70.9 32.1 7.9 121.5 0.2 5.1 10.1 4.8 3.4 30.9 8.6 15.6 109.7 1.5 14.7 7.3 39.6 16.1 0.4 0.1 1.9 4.2 4.2 27.0 12.4 44.6 1.8 2.1 213.6 2.0 22.9 27.4 1.5 6.3 1.3 39.5 42.5 74.4 5.8 26.9 271.3 0.2 6.1 0.6 6.8 3.7 24.2 0.9 17.8 60.9 0.6 40.2 0.0 158.8 279.6 1.8 0.0 33.8 0.1 12.9 0.0 16.4 36.6 25.4 39.5 35.1 40.8 6.7 13.9 0.1 4.0 10.8 0.8 7.6 0.0 4.7 MT1E "MT1, MTD" ENSG00000169715 "Metallothionein 1E" P04732 16 56625475-56627112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1787.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 4001.6;Paneth cells: 4625.0;Proximal enterocytes: 5720.1;Proximal tubular cells: 8933.3;Undifferentiated cells: 2966.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 5.8;T-cells: 20.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 1095.1;LHCN-M2: 827.5;RPTEC TERT1: 946.2;U-2 OS: 527.7" HPA041152 Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA041152: AB_2732490" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.77e-2)" "unprognostic (1.19e-2)" "unprognostic (3.63e-1)" "unprognostic (9.80e-2)" "unprognostic (7.85e-2)" "unprognostic (3.45e-2)" "unprognostic (2.78e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (5.06e-5)" "unprognostic (1.86e-1)" "unprognostic (9.53e-2)" "unprognostic (1.97e-1)" "unprognostic (3.78e-2)" 927.5 339.2 364.4 52.2 378.0 2.8 264.0 393.5 510.1 109.2 317.9 261.4 105.1 60.3 12.6 135.4 299.6 40.9 128.8 354.1 378.2 497.9 1787.5 230.3 11.7 376.7 390.6 72.4 537.3 16.3 53.3 19.1 394.6 240.3 189.3 36.8 94.7 20.6 323.0 192.4 357.7 85.5 366.2 30.3 584.7 11.5 400.8 4.0 382.6 92.5 8.0 89.1 140.9 355.9 102.2 0.0 0.0 0.0 154.5 177.0 1.6 263.8 278.6 70.7 82.1 0.9 133.0 0.0 20.3 91.6 10.7 216.7 241.2 1095.1 96.8 102.7 0.0 4.1 139.4 17.5 69.2 0.6 0.6 122.7 362.4 185.5 211.6 426.7 43.5 0.1 0.2 0.7 827.5 0.2 0.4 67.3 94.3 0.0 1.1 0.3 0.0 2.9 946.2 0.0 14.2 0.7 0.7 0.2 1.0 17.4 0.5 124.1 108.6 0.4 527.7 82.5 51.5 0.5 1.9 2.8 296.9 170.2 0.9 0.0 2.9 0.0 14.7 2.1 5.0 0.5 8.2 20.3 5.8 0.0 3.7 14.7 0.1 0.2 1.8 0.3 20.6 3.8 364.4 378.0 393.5 510.1 354.1 378.2 376.7 390.6 394.6 366.2 400.8 355.9 1237.9 394.2 158.2 83.9 59.6 178.6 240.1 86.9 306.2 0.0 214.2 311.0 106.8 589.0 168.4 496.6 0.0 18.4 32.7 2403.7 1402.9 392.8 1.8 710.8 161.7 210.0 241.9 186.9 0.2 193.7 908.6 522.8 880.2 1646.2 28.5 184.3 222.8 4001.6 34.9 0.0 0.2 2467.0 22.4 110.6 29.0 4.6 149.5 121.0 110.3 8.4 61.9 0.0 1.0 7.5 2.0 314.3 4625.0 51.1 20.6 998.6 5720.1 8933.3 137.6 0.0 216.9 818.8 513.7 3.2 3.7 286.4 148.0 79.8 96.0 14.7 2966.9 84.3 MT1M "MT1, MT1K" ENSG00000205364 "Metallothionein 1M" Q8N339 16 56632659-56633981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 398.9;liver: 562.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1333.5;Distal enterocytes: 906.4;Glandular and luminal cells: 1180.5;Hepatocytes: 1549.5;Paneth cells: 1204.8;Proximal enterocytes: 933.2;Smooth muscle cells: 680.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 181.8" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.83e-2)" "unprognostic (2.49e-1)" "unprognostic (2.10e-2)" "unprognostic (3.10e-2)" "unprognostic (4.19e-3)" "unprognostic (7.73e-2)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.13e-4)" "unprognostic (4.67e-2)" "unprognostic (3.10e-1)" "unprognostic (3.55e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-2)" "unprognostic (4.71e-2)" 398.9 27.7 214.3 32.8 233.5 0.1 145.6 240.4 316.0 31.2 183.0 134.0 21.2 14.8 4.1 83.4 95.4 42.6 36.6 207.3 219.5 47.6 562.4 116.5 4.5 225.3 226.8 16.1 145.8 2.6 10.4 2.7 232.6 57.5 140.9 24.7 31.5 6.7 48.2 44.6 113.6 37.3 217.6 7.7 98.5 3.9 246.4 5.2 64.3 4.0 2.5 33.4 26.1 213.6 0.0 0.0 0.0 0.0 39.1 27.3 0.5 1.2 9.9 1.2 2.4 0.4 0.6 0.0 7.9 6.3 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.2 0.1 3.1 0.0 14.8 0.0 23.7 0.0 0.0 0.0 0.0 19.6 0.0 0.1 0.2 13.4 0.0 1.3 0.0 0.1 0.2 181.8 0.0 0.2 0.5 0.0 0.0 0.0 1.7 0.0 2.7 5.5 0.1 0.0 1.8 0.0 0.1 0.0 0.2 4.7 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 214.3 233.5 240.4 316.0 207.3 219.5 225.3 226.8 232.6 217.6 246.4 213.6 1333.5 12.8 7.2 49.6 9.3 27.5 19.0 3.1 27.9 0.0 13.7 52.7 7.9 121.5 6.0 14.7 0.0 0.3 4.9 906.4 37.2 58.9 0.1 413.6 114.7 141.3 32.7 131.0 0.1 117.0 70.5 308.1 25.5 1180.5 15.9 11.9 82.8 1549.5 1.7 0.0 0.1 397.5 0.0 65.9 39.9 1.5 47.8 35.2 88.9 5.6 24.3 0.0 0.0 6.0 0.3 64.1 1204.8 12.0 29.4 152.4 933.2 258.6 5.2 0.0 78.9 587.1 680.1 0.0 0.5 4.7 20.2 1.0 15.5 1.2 559.6 7.9 MT2A MT2 ENSG00000125148 "Metallothionein 2A" P02795 16 56608584-56609497 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 5788.9" "Cell type enhanced" "Detected in many" "Adipocytes: 8010.7;Hepatocytes: 20955.4;Proximal enterocytes: 9666.9;Proximal tubular cells: 18370.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 30056.8;LHCN-M2: 13670.8;RPTEC TERT1: 8267.0;U-87 MG: 8331.2" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.14e-1)" "unprognostic (8.90e-2)" "unprognostic (2.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.76e-1)" "unprognostic (4.89e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (5.74e-5)" "unprognostic (5.69e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (9.52e-4)" "unprognostic (8.59e-2)" "prognostic unfavorable (2.92e-9)" "unprognostic (4.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.42e-1)" "unprognostic (1.03e-2)" 2473.0 2348.4 1352.9 558.0 1442.3 242.3 886.1 1442.7 2196.5 408.6 1146.9 678.6 272.3 156.4 87.5 584.0 574.5 785.3 400.2 1280.6 1429.1 1149.5 5788.9 1104.0 185.9 1546.3 1538.3 288.9 1625.7 63.7 210.3 278.3 1498.0 618.3 302.3 56.9 330.7 125.7 2332.2 561.1 702.8 321.4 1388.5 134.6 675.0 69.0 1615.7 96.2 869.7 475.8 71.8 975.0 395.6 1323.0 813.8 474.4 10.3 313.8 2919.3 4441.2 47.3 6998.3 4553.1 1693.0 1546.9 2.9 1499.9 137.5 941.0 709.0 502.6 874.6 394.4 30056.8 856.7 1324.8 255.2 164.3 499.3 217.2 1297.5 1020.9 99.3 2558.0 1541.9 3695.4 1569.0 1744.1 2273.5 55.6 10.6 12.4 13670.8 853.9 132.6 1393.5 677.8 0.5 3925.4 123.8 402.4 13.6 8267.0 9.8 173.8 40.0 1688.2 613.6 492.6 38.6 100.3 127.7 2200.6 7229.9 2617.8 1165.3 1973.0 8.4 20.7 14.3 8331.2 1530.1 451.2 251.3 135.0 177.0 250.2 210.3 166.7 29.3 149.8 274.6 108.7 19.1 105.0 203.1 75.8 90.3 237.8 18.2 261.4 180.8 1352.9 1442.3 1442.7 2196.5 1280.6 1429.1 1546.3 1538.3 1498.0 1388.5 1615.7 1323.0 8010.7 298.1 186.5 254.0 227.0 1833.4 1766.0 3977.6 2360.7 0.0 748.4 1639.4 110.5 762.0 642.7 1116.4 0.0 642.4 860.3 3180.2 2807.6 863.8 56.4 1744.2 565.0 2039.5 242.1 890.0 0.9 358.8 888.1 3744.8 792.0 4445.9 257.0 335.0 1201.1 20955.4 280.3 0.0 0.6 2411.2 480.1 1616.0 972.8 16.5 340.8 1565.2 626.1 47.8 387.6 0.0 224.6 25.6 15.0 702.2 6836.2 74.1 405.1 4471.7 9666.9 18370.1 434.3 0.0 1091.3 5048.3 6135.5 4.1 11.7 974.0 729.8 449.4 629.8 394.2 2478.5 439.7 MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 208.2;Oligodendrocyte precursor cells: 360.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 168.3" "Group enriched" "Detected in all" 5 "B-cells: 50.3;monocytes: 168.3" "Cell line enhanced" "Detected in many" "ASC diff: 81.4;HDLM-2: 98.7;HEL: 337.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: AB_2686756" "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (2.11e-7)" "unprognostic (6.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-1)" "unprognostic (8.92e-3)" 24.5 36.2 16.8 13.2 23.2 12.5 14.0 46.1 23.4 12.5 22.3 11.0 6.4 8.4 9.9 45.2 12.5 9.2 17.1 16.3 27.7 24.2 72.9 16.5 16.0 27.5 20.6 10.4 28.5 3.7 11.0 35.7 25.3 10.1 9.1 15.0 13.9 6.3 32.3 30.8 7.9 9.6 20.5 34.5 12.0 22.3 26.4 18.4 6.0 24.4 17.2 15.5 24.3 39.5 3.6 1.1 51.6 1.0 81.4 41.7 0.1 2.1 14.2 1.1 0.5 4.8 0.4 1.6 4.9 0.2 0.4 0.8 0.4 29.2 1.1 98.7 1.2 337.8 0.9 27.0 18.4 0.0 34.5 66.4 65.4 15.9 41.0 2.1 31.5 0.3 0.5 0.3 5.6 2.7 0.8 4.0 1.8 54.8 0.4 0.4 0.1 0.5 11.6 11.3 36.3 2.8 7.9 6.3 26.6 2.5 1.3 1.1 16.7 2.7 1.0 0.2 0.7 0.5 0.3 5.4 29.1 0.4 10.7 3.1 13.1 0.1 22.7 88.1 2.6 44.9 4.8 8.7 11.8 50.3 2.2 6.8 2.2 2.2 168.3 0.2 0.5 29.2 16.8 23.2 46.1 23.4 16.3 27.7 27.5 20.6 25.3 20.5 26.4 39.5 33.0 0.0 26.9 15.7 92.0 35.8 81.4 41.2 9.6 0.0 8.0 19.9 34.9 22.8 30.9 66.2 0.0 36.0 51.4 10.7 21.5 17.6 54.2 25.5 0.9 32.2 44.2 17.2 40.4 5.2 2.3 30.5 26.5 9.7 46.3 0.9 70.3 78.1 74.2 0.0 208.2 17.1 61.1 167.1 116.2 62.1 3.7 96.7 26.6 114.3 90.2 0.0 78.2 360.4 178.4 32.6 15.9 4.5 12.6 71.9 1.2 19.9 42.0 0.0 39.5 25.2 17.3 2.5 10.7 86.1 63.4 94.4 22.7 1.8 15.8 59.2 N4BP2L1 CG018 ENSG00000139597 "NEDD4 binding protein 2 like 1" Q5TBK1 13 32400723-32428311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 23.8;JURKAT: 22.2;NB-4: 61.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038971, HPA057219" Approved Approved Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA038971: AB_10673408, HPA057219: " "unprognostic (2.66e-3)" "unprognostic (2.38e-3)" "unprognostic (3.63e-2)" "unprognostic (5.32e-2)" "unprognostic (5.09e-2)" "unprognostic (3.40e-2)" "prognostic favorable (3.11e-4)" "unprognostic (6.91e-3)" "unprognostic (2.30e-1)" "unprognostic (9.37e-2)" "unprognostic (2.30e-2)" "unprognostic (1.20e-3)" "unprognostic (4.56e-2)" "unprognostic (1.04e-1)" "unprognostic (2.30e-1)" "unprognostic (3.29e-2)" "unprognostic (2.57e-3)" 24.8 11.9 34.0 14.9 33.8 49.5 26.9 32.9 41.1 23.7 32.3 20.3 15.6 19.5 16.1 11.2 26.3 12.6 12.4 34.2 36.2 15.4 85.6 30.2 26.6 29.0 31.1 45.2 20.3 8.6 37.1 13.5 28.4 21.7 14.6 7.9 12.4 11.6 13.8 27.5 21.1 13.0 28.9 30.1 13.8 4.4 37.2 32.0 17.0 9.7 17.9 16.6 20.5 32.7 0.9 0.3 1.3 0.5 5.0 4.0 0.4 0.6 2.2 1.2 2.0 3.8 5.1 10.3 1.4 1.1 3.7 0.1 3.7 0.3 1.6 15.5 2.3 23.8 1.4 11.4 7.8 9.0 1.4 2.8 0.8 1.0 1.0 9.0 0.8 22.2 0.0 18.3 1.0 0.8 18.6 61.4 1.9 0.0 0.5 17.5 0.6 8.8 4.9 1.8 3.4 4.2 3.7 0.1 1.7 2.4 0.5 16.8 0.4 0.5 0.3 0.3 0.1 10.4 6.6 0.5 0.6 3.4 0.7 59.0 49.3 13.9 18.0 47.2 15.9 28.6 17.5 22.4 43.7 33.0 23.9 20.8 12.5 32.1 34.4 56.0 27.9 36.7 34.0 33.8 32.9 41.1 34.2 36.2 29.0 31.1 28.4 28.9 37.2 32.7 46.1 44.8 27.6 53.2 51.4 30.1 29.6 8.7 23.9 10.6 26.6 22.6 4.3 17.2 16.5 5.5 0.0 22.3 74.8 5.5 9.8 15.0 22.5 23.0 5.7 36.1 37.9 25.5 71.7 8.5 1.1 26.2 6.1 4.8 8.8 16.0 21.0 67.2 22.5 0.0 60.4 9.2 24.4 46.6 102.7 22.7 27.4 54.6 30.2 40.3 110.2 7.2 47.4 72.9 43.4 4.4 12.5 22.2 38.4 24.5 25.8 9.8 8.1 2.2 78.9 48.9 40.4 1.4 2.8 15.2 35.4 10.4 44.0 2.5 12.9 16.5 NDST1 "HSST, NST1" ENSG00000070614 "N-deacetylase and N-sulfotransferase 1" P52848 5 150485818-150558211 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 1.4;classical monocyte: 5.5;eosinophil: 3.6;intermediate monocyte: 1.7;myeloid DC: 4.2;neutrophil: 5.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 10 "dendritic cells: 4.2;granulocytes: 5.4;monocytes: 5.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060532 Approved NA NA 1400000 "Cluster 14: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA060532: AB_2684310" "unprognostic (1.36e-1)" "unprognostic (5.54e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.77e-1)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.97e-3)" "unprognostic (6.92e-2)" "unprognostic (7.45e-2)" "unprognostic (2.46e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.08e-2)" 37.2 22.7 39.4 14.0 45.1 7.6 28.6 43.8 38.9 16.0 3.9 17.6 12.5 17.3 7.9 38.8 14.7 15.2 26.8 30.8 30.7 15.4 42.6 34.3 7.3 62.6 48.8 23.0 39.7 20.5 6.7 12.2 50.3 14.5 9.5 13.9 37.4 16.8 23.6 34.2 17.4 19.2 47.8 43.4 16.0 14.5 51.5 4.2 22.9 13.0 9.9 14.1 18.7 60.0 32.4 28.3 46.1 56.4 45.3 44.9 46.3 58.1 75.9 56.8 84.8 84.1 33.3 22.0 57.6 116.8 91.0 54.4 25.1 118.0 37.6 2.6 38.9 26.0 18.5 13.2 33.5 19.5 45.5 61.6 48.1 68.7 31.0 56.9 78.3 12.9 25.3 7.8 56.3 27.5 2.3 6.2 21.6 9.1 33.0 37.6 38.4 9.8 33.4 32.5 13.8 48.3 35.2 108.5 46.3 32.7 58.3 4.8 38.8 96.4 86.2 42.3 48.3 17.1 4.7 8.1 79.2 30.1 38.0 1.4 5.5 3.6 0.1 1.7 0.0 0.4 0.0 0.4 4.2 0.1 0.0 0.2 5.4 0.0 4.7 0.3 0.0 2.8 39.4 45.1 43.8 38.9 30.8 30.7 62.6 48.8 50.3 47.8 51.5 60.0 29.8 38.5 8.7 23.8 1.9 5.7 3.5 14.4 6.2 11.6 29.9 15.4 11.5 17.2 9.6 16.5 8.4 8.6 0.5 20.9 1.9 10.4 0.7 5.5 7.7 35.5 1.2 3.2 12.0 10.5 11.3 11.0 2.0 6.8 1.3 20.4 31.8 47.5 7.7 13.5 11.7 5.3 8.2 14.4 7.6 1.9 12.5 8.7 10.6 16.9 7.4 12.1 0.0 12.1 39.7 18.8 6.6 32.0 3.7 7.9 17.8 8.8 3.8 11.3 0.0 8.7 11.5 0.7 1.6 17.4 12.4 4.5 1.2 11.8 5.8 5.3 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 121.0;Hofbauer cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: AB_2150651, HPA056828: AB_2683250" "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 18.0 6.1 33.5 32.6 34.3 19.6 14.7 28.1 32.4 26.1 26.5 22.3 17.5 12.2 3.4 8.5 11.2 25.4 7.4 31.8 37.0 17.2 68.2 24.3 27.4 49.8 41.2 9.0 16.7 1.9 6.1 30.2 33.9 19.6 22.5 11.3 20.6 16.7 8.2 5.4 25.8 18.7 34.4 16.6 27.1 7.8 44.2 10.2 7.3 3.1 31.7 24.3 6.4 30.4 31.8 50.0 47.8 18.8 88.3 113.9 59.3 38.8 61.1 58.4 48.4 47.7 57.0 38.2 61.0 74.6 133.2 5.9 24.7 111.7 39.4 43.7 21.8 104.4 42.1 85.4 105.2 19.4 250.0 152.8 17.8 55.4 56.9 152.3 64.3 17.6 19.5 1.7 105.6 32.6 0.9 20.8 12.2 163.7 45.5 40.6 35.6 19.6 62.6 11.4 21.4 7.5 12.6 23.6 54.5 48.3 51.4 76.4 127.5 42.2 42.8 29.5 26.7 8.4 11.4 21.6 53.5 42.3 57.5 28.1 47.6 76.4 9.2 32.1 5.9 52.5 5.5 7.8 29.0 30.2 0.9 3.8 58.8 23.3 41.4 26.9 7.6 21.6 33.5 34.3 28.1 32.4 31.8 37.0 49.8 41.2 33.9 34.4 44.2 30.4 8.4 9.6 4.7 37.9 24.5 2.4 13.8 18.9 4.6 1.0 9.4 6.5 3.3 18.6 8.8 3.7 0.0 47.1 11.3 8.5 1.9 41.3 18.2 9.4 17.7 8.4 6.0 4.0 8.3 23.3 121.0 11.1 19.4 22.2 22.2 1.1 5.0 43.5 112.0 0.0 5.3 18.2 18.3 10.4 22.5 20.0 5.0 31.2 7.2 12.2 57.7 34.6 8.2 15.1 2.4 30.6 11.9 3.8 5.5 17.1 17.2 38.0 3.3 2.1 0.0 4.9 6.4 1.3 17.1 2.4 1.1 36.1 4.5 2.1 18.7 10.2 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122677 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 5.0;Exocrine glandular cells: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 6.8;K-562: 6.1;SCLC-21H: 6.1" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favorable (5.30e-4)" 1.2 1.4 2.0 0.8 2.3 1.1 2.0 1.5 2.6 0.8 0.8 1.5 1.4 0.8 2.6 1.1 1.4 0.6 1.8 2.4 1.9 0.8 4.1 1.2 0.6 2.5 1.8 1.4 1.8 1.2 1.2 0.5 2.7 1.2 1.3 2.0 2.3 1.0 2.6 3.8 1.9 0.8 1.6 1.1 1.3 0.7 2.0 1.0 1.6 1.5 0.8 0.9 0.8 3.6 2.6 1.5 0.6 0.0 1.3 1.2 0.0 2.6 0.8 0.9 0.5 0.1 2.1 0.0 6.8 1.9 0.2 3.0 0.0 1.7 0.7 0.1 0.9 0.4 1.0 0.1 2.0 0.0 1.7 2.1 2.5 1.0 0.9 0.6 2.1 0.0 6.1 0.1 2.1 2.8 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.1 1.4 2.8 6.1 0.1 5.3 4.3 1.6 0.6 3.1 1.7 0.4 0.2 1.3 1.8 0.1 0.1 0.0 0.1 0.1 0.0 2.6 0.5 4.4 0.4 0.6 4.9 0.8 2.3 1.1 0.5 4.7 1.3 1.5 1.0 0.3 1.6 2.3 0.6 1.3 1.8 2.0 2.3 1.5 2.6 2.4 1.9 2.5 1.8 2.7 1.6 2.0 3.6 0.8 0.0 2.2 0.3 0.2 1.9 1.4 1.4 1.8 0.4 1.5 2.0 0.9 1.5 2.3 0.0 0.0 0.4 0.0 0.2 0.0 2.9 0.0 0.6 1.3 0.3 3.5 5.0 1.0 3.7 0.0 0.8 1.5 0.5 1.3 0.8 0.4 1.1 1.2 0.0 0.7 0.3 0.0 0.8 0.6 0.0 0.6 1.5 1.8 1.0 0.5 1.1 0.0 1.5 1.2 2.0 0.3 0.0 0.0 0.2 0.6 1.2 0.8 1.0 0.0 0.3 0.8 0.2 0.2 1.3 1.8 0.4 0.1 1.1 0.5 0.5 NME4 "NDPKD, nm23-H4, NM23H4" ENSG00000103202 "NME/NM23 nucleoside diphosphate kinase 4" O00746 16 396725-410367 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid transport, Nucleotide metabolism, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 250.5;Erythroid cells: 311.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045997, HPA072588" Approved Supported Mitochondria Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "CAB045997: AB_11126630, HPA072588: AB_2686538" "unprognostic (3.27e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (3.70e-2)" "unprognostic (7.16e-3)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (4.46e-3)" "unprognostic (1.98e-1)" "unprognostic (3.12e-1)" "unprognostic (3.74e-2)" "unprognostic (7.79e-3)" "prognostic unfavorable (1.61e-7)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "unprognostic (3.08e-1)" 89.3 136.1 78.3 26.2 75.6 127.7 72.9 73.5 101.5 88.1 77.3 192.9 21.9 79.5 55.7 50.1 89.1 41.2 101.2 76.4 81.7 60.4 175.2 48.3 21.1 88.6 77.9 86.8 43.7 56.7 64.3 30.8 79.8 143.7 23.5 11.1 70.4 81.9 34.7 31.4 59.7 51.9 78.6 43.8 97.7 44.7 80.3 29.3 51.6 27.2 15.8 145.6 64.3 73.6 1.0 305.4 265.6 366.7 104.0 181.0 59.5 143.6 170.4 211.8 180.6 205.4 176.2 3.0 105.8 230.2 76.9 3.9 145.0 153.9 62.0 126.5 218.7 151.9 40.2 279.9 195.7 111.0 53.1 234.7 79.8 130.5 12.8 152.2 137.6 210.7 159.6 25.8 160.4 255.4 98.5 139.2 271.8 76.1 67.8 485.8 59.3 79.0 150.6 1.2 77.7 419.2 36.8 2.7 139.9 97.2 178.3 257.5 174.0 149.7 216.8 101.8 36.8 2.7 2.0 83.1 65.8 19.8 177.2 12.9 13.3 39.8 14.9 11.9 12.7 27.6 14.4 16.3 17.6 29.9 26.0 13.4 4.2 2.5 10.6 58.3 0.9 10.7 78.3 75.6 73.5 101.5 76.4 81.7 88.6 77.9 79.8 78.6 80.3 73.6 52.2 0.0 13.9 18.6 40.6 32.2 56.3 49.0 40.9 15.2 116.6 135.8 44.5 52.9 25.1 58.8 2.1 71.7 45.7 19.3 250.5 116.5 5.0 30.8 113.3 55.3 45.1 311.8 16.8 40.3 26.1 87.3 29.6 59.8 29.9 199.9 55.6 132.2 131.2 8.4 21.1 38.6 26.4 46.5 68.6 21.6 89.2 35.4 62.2 10.3 46.5 45.9 19.6 10.1 3.6 58.3 23.8 94.8 34.5 121.8 9.0 75.5 7.9 5.6 52.6 40.1 105.8 1.7 32.7 38.6 24.6 21.8 26.2 89.4 54.9 60.9 NPW PPL8 ENSG00000183971 "Neuropeptide W" Q8N729 16 2009926-2020755 "Predicted intracellular proteins, Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 10.6" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 188.1;Enteroendocrine cells: 158.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 6 "NB-4: 43.5;PC-3: 35.6;RPMI-8226: 74.7;SCLC-21H: 118.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.2" HPA064874 Approved "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "HPA064874: AB_2685378" "unprognostic (7.54e-2)" "unprognostic (4.45e-3)" "unprognostic (3.20e-1)" "unprognostic (4.31e-3)" "unprognostic (8.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.20e-2)" "unprognostic (6.26e-3)" "unprognostic (2.37e-1)" "unprognostic (1.81e-5)" "unprognostic (6.53e-3)" "unprognostic (1.26e-1)" "unprognostic (4.41e-1)" "unprognostic (3.43e-2)" 0.4 0.1 1.0 0.4 0.7 1.2 0.1 0.6 3.6 1.1 1.1 0.5 0.6 1.1 1.3 0.4 0.6 0.0 0.1 0.7 1.9 0.4 10.6 0.1 0.2 0.7 0.9 0.4 0.4 0.0 2.7 0.1 0.7 0.3 0.1 0.0 0.1 0.2 0.0 1.7 0.2 0.2 0.5 0.7 2.4 1.2 2.5 0.0 0.2 0.0 0.4 0.2 0.6 1.0 0.4 1.7 0.2 2.5 0.4 0.0 0.7 0.9 0.2 0.5 1.0 3.8 1.5 0.4 0.1 0.8 0.6 0.8 1.1 0.3 0.5 1.8 2.9 0.1 3.0 1.7 2.3 0.4 0.1 1.0 1.3 0.9 1.9 0.1 0.0 2.5 10.8 1.7 0.1 0.9 0.4 43.5 1.9 1.5 35.6 10.5 0.0 74.7 0.4 0.0 118.8 9.9 1.3 2.2 0.3 0.6 5.6 4.4 1.7 0.3 0.6 0.5 0.1 3.6 1.1 1.1 0.6 0.9 0.4 1.2 0.7 0.7 0.2 0.4 0.6 0.4 0.1 0.0 0.7 0.4 0.2 0.1 1.5 0.6 0.2 0.4 0.4 0.2 1.0 0.7 0.6 3.6 0.7 1.9 0.7 0.9 0.7 0.5 2.5 1.0 2.5 0.0 0.0 0.0 2.9 2.0 3.2 1.9 4.0 1.5 2.7 7.1 0.3 0.0 2.0 0.0 0.0 1.2 0.1 6.0 0.0 0.5 0.9 9.9 188.1 4.4 158.5 12.2 0.4 0.2 0.9 14.0 15.8 8.5 8.9 0.5 0.7 35.9 2.3 0.0 0.7 35.8 0.0 0.3 0.3 2.1 2.1 1.6 3.6 0.0 0.1 0.0 0.0 0.0 0.1 2.1 12.4 2.2 1.5 11.9 3.2 0.8 0.3 0.3 0.0 0.5 2.7 8.8 35.4 4.1 2.3 1.6 2.3 1.6 3.9 4.6 NSUN6 "ARL5B-AS1, FLJ23743, NOPD1" ENSG00000241058 "NOP2/Sun RNA methyltransferase 6" Q8TEA1 10 18545561-18659285 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 61.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045902 Approved Approved "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "HPA045902: AB_10962354" "unprognostic (7.34e-2)" "unprognostic (1.69e-2)" "unprognostic (3.10e-3)" "unprognostic (9.50e-2)" "unprognostic (4.92e-2)" "unprognostic (8.33e-3)" "unprognostic (1.63e-2)" "prognostic favorable (8.42e-4)" "unprognostic (1.60e-1)" "unprognostic (2.45e-1)" "unprognostic (9.96e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (2.23e-1)" "unprognostic (7.53e-3)" "unprognostic (3.18e-2)" "unprognostic (2.00e-3)" 6.4 12.2 13.6 7.5 14.3 12.4 9.3 16.0 15.9 9.0 13.5 6.1 8.6 9.6 12.2 5.7 8.7 6.0 8.6 14.0 14.1 10.6 61.1 6.5 11.3 13.8 14.8 12.7 12.0 7.8 17.2 6.5 14.7 10.5 8.4 12.9 8.4 5.6 4.5 9.1 8.7 6.1 13.9 9.8 8.5 17.5 13.8 11.8 12.0 4.8 10.9 9.1 7.6 17.6 7.5 6.3 16.6 12.3 8.1 11.1 7.2 10.3 2.5 8.4 11.3 12.0 11.2 17.0 4.3 4.0 5.9 11.0 17.1 10.8 10.8 16.6 13.9 17.8 8.8 14.5 8.3 8.1 11.6 8.6 10.3 8.0 5.5 8.3 3.9 20.0 25.1 16.1 8.2 4.2 18.6 9.3 8.5 14.8 4.8 13.1 8.6 17.4 6.3 9.1 8.9 11.0 8.7 9.0 7.3 11.3 5.8 6.4 6.7 7.0 8.1 12.8 7.6 9.9 11.0 18.8 5.0 14.5 4.3 1.5 3.5 2.8 4.4 4.7 7.0 8.0 6.3 5.6 2.9 6.1 7.8 6.7 1.6 5.3 8.2 4.0 10.5 2.5 13.6 14.3 16.0 15.9 14.0 14.1 13.8 14.8 14.7 13.9 13.8 17.6 75.4 9.6 15.1 57.8 34.9 28.7 17.1 11.0 30.1 33.2 32.4 34.7 8.1 18.6 13.6 9.2 22.9 10.1 39.6 19.5 5.9 10.0 19.7 23.6 38.9 37.5 14.5 20.8 43.5 12.7 8.0 19.2 40.2 49.0 17.7 32.0 26.7 86.6 7.4 25.2 45.0 24.5 18.3 24.2 52.4 12.7 25.7 28.5 12.4 23.4 15.3 15.3 17.5 43.7 57.6 11.1 20.0 17.0 31.0 10.1 40.2 10.9 14.5 28.9 13.1 20.1 19.1 49.5 21.8 21.3 26.7 6.7 31.0 26.7 18.7 14.2 OR2V1 "OR2V1P, OST265" ENSG00000185372 "Olfactory receptor family 2 subfamily V member 1" Q8NHB1 5 181123122-181131169 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 1.6;retina: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049953 Uncertain NA NA "Cluster 15: Liver - Metabolism" "HPA049953: AB_2680971" 0.1 0.0 0.4 0.1 0.4 0.3 0.4 0.8 0.8 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.4 0.0 0.0 0.7 0.6 0.1 1.6 0.1 0.2 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.6 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.0 0.0 0.7 0.2 0.1 0.3 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.8 0.8 0.7 0.6 0.4 0.2 0.3 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCBD1 "DCOH, PCBD, PCD" ENSG00000166228 "Pterin-4 alpha-carbinolamine dehydratase 1" P61457 10 70882280-70888565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation" "Activator, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 429.5" "Cell type enhanced" "Detected in all" "Distal tubular cells: 453.9;Hepatocytes: 603.7;Proximal tubular cells: 877.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 527.8;Hep G2: 527.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037575, HPA061723" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA037575: AB_10671761, HPA061723: AB_2684594" "unprognostic (1.02e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (3.69e-1)" "unprognostic (5.39e-2)" "unprognostic (4.80e-3)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (2.40e-2)" "unprognostic (2.95e-1)" "unprognostic (5.63e-2)" "unprognostic (3.38e-2)" "unprognostic (9.26e-2)" "unprognostic (1.74e-1)" "unprognostic (5.76e-2)" "unprognostic (7.43e-3)" 77.3 102.9 115.0 31.0 111.8 21.8 67.9 111.9 140.7 58.0 114.1 83.9 54.4 48.2 91.2 54.3 111.5 47.4 152.3 109.3 136.9 165.1 429.5 57.9 31.1 125.4 138.5 64.2 174.9 135.1 61.5 33.4 139.4 73.8 88.3 48.6 49.9 78.4 109.7 25.7 64.0 75.6 119.7 25.6 84.8 20.0 131.8 25.8 86.3 109.1 35.8 69.3 39.2 118.9 158.3 374.3 21.4 223.8 80.9 76.0 29.4 50.0 84.5 77.7 61.6 527.8 270.3 32.2 141.4 56.3 57.9 101.7 138.9 81.3 53.2 86.2 251.9 28.6 57.5 527.1 84.9 28.5 99.2 74.1 88.5 76.5 35.8 114.1 212.3 19.9 57.1 2.8 55.2 270.2 3.5 94.7 30.1 420.5 346.0 15.1 29.7 103.6 328.6 164.7 94.0 158.8 41.5 277.1 111.5 59.9 81.1 53.8 86.2 12.7 102.9 18.9 123.8 1.1 6.7 1.1 68.3 93.1 19.5 0.2 24.8 8.7 19.6 47.1 15.3 25.7 25.8 28.3 49.6 10.9 8.4 17.1 1.6 19.6 34.4 35.8 41.1 18.7 115.0 111.8 111.9 140.7 109.3 136.9 125.4 138.5 139.4 119.7 131.8 118.9 25.5 41.7 91.5 8.5 25.9 49.8 169.1 88.2 103.0 39.0 197.9 249.6 151.5 138.7 86.0 187.6 6.2 124.6 18.5 113.8 453.9 185.0 2.3 138.7 49.3 40.8 176.4 36.2 4.9 169.9 81.6 82.2 86.6 175.3 31.1 64.6 37.9 603.7 180.3 35.3 8.5 313.3 65.1 79.9 55.7 11.2 67.4 73.1 78.2 5.6 68.0 153.0 22.6 9.0 4.6 154.8 164.7 95.5 35.1 212.7 232.1 877.7 78.4 33.2 85.5 57.2 63.3 4.4 12.3 147.8 45.7 77.6 32.6 95.9 230.2 187.5 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 153.6;liver: 160.0;lymphoid tissue: 81.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 231.6;Horizontal cells: 196.9;Oligodendrocytes: 561.9;Theca cells: 106.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.2;CACO-2: 35.7;HEK 293: 60.3;Hep G2: 53.8;OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" NA NA 480000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 5.3 2.2 17.5 3.0 67.3 1.1 11.2 57.8 37.0 2.2 4.2 16.5 6.8 2.0 3.3 9.0 2.8 3.1 20.0 19.3 34.1 3.2 160.0 3.6 2.5 113.0 64.5 6.1 2.6 0.6 5.1 32.0 95.6 3.1 14.8 7.6 2.8 0.6 11.4 10.1 10.1 3.6 42.9 81.4 9.8 13.0 54.0 20.9 2.2 16.3 1.8 3.7 2.6 153.6 19.7 14.6 2.6 0.9 0.2 0.4 47.2 0.7 2.5 0.0 0.1 35.7 8.3 0.4 2.4 0.6 1.1 11.4 12.5 1.5 0.0 2.8 60.3 33.5 8.4 53.8 1.6 4.5 0.4 0.3 7.5 0.2 0.2 0.2 0.1 4.3 24.5 0.2 0.0 8.8 0.1 4.7 9.3 65.9 6.5 0.2 0.4 4.4 4.4 25.4 7.3 8.6 26.2 1.5 9.1 6.6 2.2 21.9 0.2 0.3 1.2 0.3 0.2 0.5 0.6 0.7 0.2 0.6 7.3 0.8 0.2 0.9 0.2 0.4 0.3 0.5 0.4 0.2 0.1 1.0 0.6 0.5 0.4 3.3 1.3 0.4 0.1 1.2 17.5 67.3 57.8 37.0 19.3 34.1 113.0 64.5 95.6 42.9 54.0 153.6 1.7 3.2 0.6 2.9 1.3 0.4 0.3 0.9 0.6 1.7 15.4 6.6 2.0 8.6 1.4 1.8 20.9 6.7 0.6 22.6 0.0 0.6 1.6 4.7 21.6 4.9 0.0 3.2 19.4 0.8 24.3 15.5 1.5 6.9 0.0 4.2 12.5 231.6 1.4 196.9 30.8 3.7 0.0 5.2 1.1 2.4 10.5 1.7 0.0 5.6 1.0 1.7 3.1 25.6 561.9 7.3 8.2 0.0 0.0 1.7 2.3 0.1 1.2 1.6 0.0 2.0 1.0 4.7 2.4 0.9 0.1 3.3 1.0 106.5 8.5 0.2 PHYHD1 MGC16638 ENSG00000175287 "Phytanoyl-CoA dioxygenase domain containing 1" Q5SRE7 9 128920966-128942041 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Muller glia cells: 139.3;Proximal tubular cells: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 13.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 13.0" "Cell line enhanced" "Detected in many" "ASC diff: 46.5;ASC TERT1: 32.7;BEWO: 50.6;HSkMC: 28.3;RPTEC TERT1: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012115 Approved "Nuclear speckles" NA NA 36000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA012115: AB_1859448" "unprognostic (1.18e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.09e-3)" "unprognostic (2.16e-1)" "unprognostic (1.17e-2)" "unprognostic (4.49e-2)" "unprognostic (5.37e-3)" "unprognostic (1.35e-1)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (3.70e-2)" "prognostic favorable (6.38e-10)" "unprognostic (1.10e-2)" "unprognostic (3.09e-1)" "unprognostic (2.14e-1)" "unprognostic (9.83e-3)" 28.2 25.7 41.9 3.2 39.9 8.4 34.6 37.9 40.8 39.8 41.7 24.4 2.3 33.8 38.3 25.6 28.5 13.2 35.1 36.3 46.9 49.9 78.7 23.1 4.5 48.1 51.9 39.1 70.2 15.6 15.5 9.6 46.5 36.8 3.8 41.8 40.0 30.0 29.3 43.7 12.4 15.4 48.1 14.7 33.4 7.2 47.9 6.8 43.0 12.8 4.6 25.9 25.6 48.7 0.2 0.5 0.4 0.8 46.5 32.7 50.6 3.7 0.0 3.4 6.0 1.8 0.5 0.7 0.4 3.0 0.3 0.7 0.4 0.3 2.9 0.5 5.4 0.1 6.7 18.0 15.1 0.8 0.6 28.3 1.0 0.4 0.2 0.2 0.3 0.3 0.3 1.2 24.3 0.4 0.5 0.7 17.0 0.2 0.2 20.5 9.7 0.3 78.9 0.7 1.1 0.4 0.5 0.3 0.3 11.4 4.7 0.6 1.3 0.7 2.1 0.7 0.5 0.4 0.9 20.7 0.3 0.4 0.7 1.3 0.2 0.2 1.3 0.3 0.3 2.8 0.4 0.5 1.7 0.7 1.8 1.9 0.8 2.2 0.4 13.0 0.3 0.5 41.9 39.9 37.9 40.8 36.3 46.9 48.1 51.9 46.5 48.1 47.9 48.7 8.5 32.1 34.3 51.6 3.7 22.0 63.2 26.8 57.5 9.4 40.0 46.9 19.8 10.0 31.0 33.1 29.2 58.8 3.4 0.7 119.3 11.4 0.4 27.0 26.0 9.5 1.2 12.0 1.2 15.8 30.0 34.5 7.7 53.8 0.0 42.8 31.8 82.2 10.7 3.3 0.8 2.4 4.1 3.2 5.5 4.2 68.6 3.1 12.4 5.6 0.1 139.3 4.1 1.0 0.7 14.2 0.5 66.2 2.6 19.3 0.0 161.5 14.6 67.5 52.6 48.1 17.8 0.9 3.9 32.7 24.3 30.9 2.7 44.6 1.4 35.0 PIGL ENSG00000108474 "Phosphatidylinositol glycan anchor biosynthesis class L" Q9Y2B2 17 16217191-16351797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "GPI-anchor biosynthesis" Hydrolase "Deafness, Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.7;Inhibitory neurons: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012739 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" No No "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA012739: AB_1855367" "unprognostic (3.07e-2)" "unprognostic (2.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" "unprognostic (7.70e-2)" "unprognostic (6.14e-2)" "unprognostic (9.39e-5)" "unprognostic (1.11e-2)" "unprognostic (1.15e-2)" "unprognostic (1.63e-2)" "unprognostic (6.37e-3)" "prognostic unfavorable (2.57e-4)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.19e-2)" "unprognostic (2.13e-1)" "unprognostic (3.38e-1)" "unprognostic (2.75e-3)" 9.6 8.6 8.0 6.3 8.4 5.6 10.1 9.7 10.4 8.6 8.5 8.8 10.6 8.3 11.8 8.1 8.9 6.1 5.6 7.8 8.5 9.0 14.3 7.7 7.8 7.8 7.8 10.4 10.2 6.1 10.4 6.3 8.2 9.8 8.4 6.3 8.2 6.1 5.3 11.4 10.1 5.9 7.6 7.8 10.5 8.7 8.2 6.4 10.1 3.3 8.3 7.8 8.1 9.4 12.5 16.3 11.4 9.3 16.0 15.2 4.6 6.3 8.0 10.8 19.5 17.2 15.4 6.6 13.7 6.7 6.9 17.4 14.7 8.2 15.0 13.1 38.3 12.3 13.6 21.9 17.3 5.0 7.4 12.5 20.3 19.1 22.0 10.9 13.0 20.1 14.6 7.3 8.6 11.1 9.3 11.6 4.5 25.2 8.3 9.0 9.7 15.6 12.3 6.6 6.0 8.5 6.7 4.9 14.6 29.9 5.4 4.5 7.6 9.1 6.0 6.6 19.8 5.5 0.2 10.3 12.2 12.5 6.2 0.0 2.7 4.7 4.6 2.6 4.1 3.7 6.3 3.7 2.0 2.8 6.4 5.5 0.0 4.8 1.8 5.3 5.4 2.5 8.0 8.4 9.7 10.4 7.8 8.5 7.8 7.8 8.2 7.6 8.2 9.4 8.5 9.6 21.0 19.2 10.0 4.5 9.2 9.1 11.4 11.5 9.8 9.8 2.4 7.2 13.0 12.9 10.4 15.6 9.3 7.3 5.9 6.3 3.0 7.7 11.4 6.6 7.8 11.6 46.7 7.5 8.0 8.8 11.7 6.9 5.1 14.0 5.0 10.5 5.2 6.7 45.3 11.2 10.2 3.5 4.3 2.9 7.8 5.9 3.6 26.2 3.6 5.2 9.2 24.6 34.9 9.4 9.7 11.3 12.2 8.3 9.8 5.9 10.6 12.2 0.0 9.1 7.3 16.1 8.3 7.5 6.0 9.6 11.8 9.4 12.6 10.4 PLGLB1 "PLGL, PRP-B" ENSG00000183281 "Plasminogen like B1" Q02325 2 87002559-87021852 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in all" 6 "liver: 234.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 95.9" "Cancer enriched" "Detected in single" 7 "liver cancer: 0.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.25e-2)" "unprognostic (7.25e-2)" "unprognostic (2.35e-1)" "unprognostic (1.15e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-5)" "unprognostic (7.04e-3)" "unprognostic (1.15e-1)" "unprognostic (8.53e-4)" "unprognostic (1.60e-1)" "unprognostic (4.56e-4)" "unprognostic (9.90e-3)" "unprognostic (2.96e-5)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (4.32e-2)" "unprognostic (3.98e-5)" 3.6 5.5 19.9 4.5 19.9 8.5 3.6 33.4 26.5 6.9 21.3 4.9 3.9 5.9 8.2 4.0 4.3 4.7 5.9 20.0 20.3 8.5 234.9 3.3 7.9 16.7 17.4 6.7 4.1 2.2 9.5 2.3 16.0 6.6 2.7 42.5 4.8 3.2 8.8 14.2 5.3 2.4 15.0 9.5 4.0 4.3 20.0 7.2 5.6 4.4 4.3 4.9 4.9 19.6 2.7 3.7 4.6 2.6 3.6 5.2 4.5 3.2 2.3 1.7 2.6 2.9 6.9 7.3 3.3 1.3 1.3 2.4 1.2 0.5 1.8 8.2 3.1 5.8 6.6 3.1 2.5 3.5 1.5 4.0 4.2 4.7 4.8 7.9 0.8 8.0 3.0 5.9 2.2 3.9 13.3 11.5 5.9 2.4 2.4 3.1 1.7 3.9 4.5 2.9 3.6 4.0 2.9 2.5 2.7 4.6 1.3 7.6 5.0 3.3 2.3 2.3 2.0 6.7 5.1 2.9 1.9 4.7 1.9 1.9 0.3 0.4 0.7 0.1 0.6 1.2 0.7 0.5 0.1 0.8 0.9 0.5 1.0 0.4 0.3 0.6 1.1 0.1 19.9 19.9 33.4 26.5 20.0 20.3 16.7 17.4 16.0 15.0 20.0 19.6 1.3 0.0 3.4 0.7 1.0 1.1 0.3 0.4 1.2 10.3 1.1 1.0 2.6 1.5 1.5 0.0 6.2 0.2 1.5 0.7 0.0 1.1 0.8 1.0 1.0 1.6 1.2 4.0 0.9 0.2 0.2 1.6 0.5 0.9 0.0 1.0 1.8 95.9 0.2 5.0 1.1 2.5 0.0 1.3 0.4 0.3 1.2 1.1 3.6 0.0 1.6 2.7 1.0 0.0 0.8 0.3 0.3 1.9 0.9 0.5 0.7 1.8 2.3 18.2 0.0 2.5 1.0 0.7 0.5 1.5 1.3 0.0 1.4 0.9 0.9 0.3 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 236.8;Sertoli cells: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" 58.1 34.6 46.3 35.2 51.2 16.1 41.2 48.6 56.6 65.4 46.4 47.3 37.7 65.0 30.5 21.3 51.1 42.0 71.2 44.5 47.4 45.5 78.1 44.4 15.4 49.6 50.8 54.4 39.0 36.9 29.6 83.8 52.4 34.7 23.2 10.6 75.9 40.6 40.5 27.2 35.6 78.4 44.8 31.5 35.5 11.6 52.2 7.9 34.9 41.6 12.9 42.4 36.0 53.1 112.5 91.4 51.3 239.7 343.4 190.6 39.0 330.4 436.1 170.4 287.1 105.2 71.5 63.1 339.5 367.3 125.9 93.4 75.6 115.6 115.6 66.2 78.3 34.0 136.6 137.3 212.5 21.9 162.7 234.0 59.7 206.2 81.9 573.3 305.0 14.8 97.6 30.9 180.2 71.1 5.7 58.6 22.9 115.4 131.6 25.8 100.0 141.0 98.7 24.3 19.2 77.7 137.3 97.4 164.8 80.4 48.3 55.9 298.7 190.1 141.6 236.3 161.9 71.4 123.7 38.7 425.1 75.5 316.8 0.0 40.3 2.0 17.3 34.4 3.1 1.7 3.0 8.4 32.7 3.4 1.2 6.4 35.5 5.4 32.3 4.9 2.0 22.6 46.3 51.2 48.6 56.6 44.5 47.4 49.6 50.8 52.4 44.8 52.2 53.1 19.4 0.0 7.9 9.4 3.7 7.0 8.0 22.8 8.0 5.7 17.9 17.5 18.3 8.6 8.6 11.0 2.1 39.7 8.7 14.8 3.9 30.3 1.0 11.0 62.2 33.9 8.4 3.0 4.2 9.8 236.8 47.5 17.3 24.8 0.0 20.4 36.8 37.1 46.3 6.7 5.8 12.5 4.1 26.5 8.3 2.4 44.4 16.3 10.6 15.9 17.9 7.9 15.5 3.0 9.8 22.4 15.4 24.5 19.4 8.0 41.5 16.7 4.5 3.1 105.2 77.2 47.3 0.5 3.3 7.4 5.1 33.7 5.5 37.1 16.6 3.9 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 115.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 20.3;monocytes: 22.5;T-cells: 12.6" "Cell line enhanced" "Detected in all" "Karpas-707: 695.6;WM-115: 680.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted to extracellular matrix" NA NA 1600000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 41.9 27.3 43.6 22.9 53.2 19.6 32.8 54.9 58.5 33.3 46.8 37.8 25.7 38.9 11.7 12.2 32.5 18.8 42.6 43.6 46.3 36.3 54.1 37.5 14.6 61.1 52.3 26.3 41.8 21.5 27.1 35.0 58.9 24.2 15.3 3.9 19.4 18.6 15.3 19.1 35.9 26.0 49.4 35.3 30.0 12.9 51.7 8.0 25.3 11.8 7.5 35.2 25.2 71.9 71.7 62.4 27.1 168.2 116.2 83.9 51.4 125.5 135.9 122.7 88.6 98.0 89.0 5.6 140.2 211.4 100.7 83.0 50.0 72.0 31.2 37.8 23.8 7.2 70.7 97.3 157.6 31.5 57.4 90.8 67.6 71.6 55.4 120.2 110.9 4.6 68.4 695.6 84.2 194.5 3.4 72.1 53.5 120.5 94.9 21.8 35.1 108.3 42.0 19.1 21.2 116.0 81.1 116.2 288.1 66.8 21.9 105.2 100.5 188.1 94.9 228.1 155.0 38.5 75.9 5.2 112.4 74.2 680.2 0.0 18.1 4.4 12.6 21.8 10.9 3.7 9.3 8.3 16.5 2.2 4.1 4.5 1.8 3.6 22.5 20.3 6.7 9.5 43.6 53.2 54.9 58.5 43.6 46.3 61.1 52.3 58.9 49.4 51.7 71.9 34.1 22.4 8.7 11.1 9.7 8.9 10.8 18.9 8.0 5.7 8.1 9.1 16.1 21.5 8.7 25.8 14.6 20.4 22.0 37.6 1.9 40.2 0.6 10.8 29.9 28.5 16.2 19.1 11.9 31.6 71.6 34.2 17.9 20.5 19.7 25.9 26.7 18.3 50.1 8.4 10.8 18.0 4.1 23.3 18.3 2.1 26.1 23.2 62.2 4.7 18.9 7.7 12.3 10.1 33.4 36.1 37.8 14.7 19.7 8.0 45.8 8.8 9.3 7.3 19.7 14.3 29.8 8.9 12.4 1.9 4.8 18.9 12.5 18.4 27.3 5.2 PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 77.3;Astrocytes: 151.1;Endothelial cells: 63.4;Hepatic stellate cells: 110.3;Oligodendrocyte precursor cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.5;ASC TERT1: 48.2;hTERT-RPE1: 62.1;HUVEC TERT2: 50.8;TIME: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA002276: AB_1855479" "unprognostic (3.73e-3)" "unprognostic (4.03e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.62e-1)" "unprognostic (6.77e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-4)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.97e-3)" 60.2 43.8 30.2 9.4 28.2 2.3 41.9 30.9 32.5 28.9 11.6 27.4 6.8 30.1 15.7 23.2 41.2 45.6 28.0 28.7 38.5 25.3 69.0 37.4 10.5 39.3 44.0 36.4 20.5 4.3 11.2 56.4 32.6 13.8 25.2 13.7 23.6 25.8 7.4 16.1 13.6 33.7 36.9 30.1 14.4 21.6 41.8 6.6 31.2 18.8 6.7 19.8 25.5 32.2 0.0 9.9 1.7 0.0 60.5 48.2 0.3 11.5 15.7 5.0 10.9 1.0 12.6 0.0 12.3 21.0 5.0 1.4 2.4 1.1 2.8 0.1 0.1 5.0 7.9 1.3 28.1 0.1 1.3 29.6 1.6 10.4 3.0 62.1 50.8 0.0 0.2 0.9 7.4 0.3 0.0 0.1 2.1 5.1 3.4 0.0 0.8 0.0 0.1 0.0 0.6 0.0 20.1 0.1 3.9 2.5 0.7 0.6 106.4 10.4 2.6 23.6 2.1 0.3 0.0 0.0 2.6 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 28.2 30.9 32.5 28.7 38.5 39.3 44.0 32.6 36.9 41.8 32.2 77.3 3.2 10.3 151.1 1.0 10.8 5.6 0.8 12.0 0.6 10.2 8.6 4.1 25.8 6.0 3.7 0.0 0.7 0.3 27.4 0.0 8.2 1.1 3.6 11.6 63.4 10.3 15.6 1.7 11.6 0.5 57.1 2.0 1.5 1.3 7.0 110.3 44.1 0.8 0.0 0.6 11.7 0.0 7.1 11.8 3.8 42.9 1.1 3.6 40.3 0.1 51.4 0.0 61.3 0.6 4.7 13.3 32.4 2.8 2.6 6.4 28.3 6.4 1.5 0.0 18.9 23.6 1.2 0.9 4.8 8.7 0.8 1.8 20.0 8.1 2.7 PNPO PDXPO ENSG00000108439 "Pyridoxamine 5'-phosphate oxidase" Q9NVS9 17 47941506-47949308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridoxine biosynthesis" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 88.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 62.6;Hepatocytes: 53.4;Proximal tubular cells: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023204, HPA027776" Enhanced Approved Nucleoplasm,Cytosol NA NA 450000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA023204: AB_1855506, HPA027776: AB_10601246" "unprognostic (1.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (2.62e-1)" "unprognostic (1.97e-2)" "unprognostic (6.65e-2)" "unprognostic (8.34e-2)" "unprognostic (2.02e-3)" "unprognostic (7.47e-3)" "unprognostic (8.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.74e-1)" 7.3 15.8 16.5 6.2 15.9 3.5 10.6 16.7 22.0 7.0 12.9 8.8 10.2 5.0 11.6 10.7 10.1 6.6 13.2 16.0 21.9 35.1 88.8 6.4 6.9 19.1 21.2 5.8 10.9 26.6 9.2 7.0 20.6 8.0 8.6 5.4 10.4 7.8 21.1 6.7 9.6 6.1 16.5 7.2 8.6 6.6 20.6 5.8 17.8 19.6 7.7 6.7 7.3 14.3 37.9 30.9 2.4 5.8 15.3 11.7 0.0 12.2 7.7 14.0 11.9 51.1 27.6 35.2 57.4 12.7 5.5 22.0 19.4 34.7 20.3 43.4 16.4 24.6 13.9 53.6 16.3 22.6 16.6 15.4 26.9 25.8 32.7 13.1 18.0 26.1 24.4 12.2 16.5 28.3 25.3 7.8 4.5 37.4 37.1 18.8 10.4 26.2 40.2 19.5 12.1 9.5 11.2 18.6 10.7 8.5 32.4 9.1 19.1 22.6 12.8 22.2 26.2 27.8 34.0 19.0 18.4 19.2 11.7 2.5 12.3 2.8 7.2 17.7 8.2 6.7 6.3 7.6 13.5 5.3 8.2 8.1 1.1 7.9 11.9 9.8 7.0 10.3 16.5 15.9 16.7 22.0 16.0 21.9 19.1 21.2 20.6 16.5 20.6 14.3 7.6 12.8 13.9 7.5 3.9 1.5 6.7 5.0 5.7 1.1 16.2 14.4 1.9 18.6 6.8 12.9 4.2 8.4 7.8 7.3 62.6 18.2 0.8 11.2 6.4 5.9 3.6 7.4 4.2 15.6 1.9 5.3 4.6 13.3 12.7 8.8 6.4 53.4 17.2 3.3 6.2 11.6 2.0 11.4 2.4 0.9 9.9 10.6 1.8 2.8 8.6 7.1 3.1 2.5 3.2 15.0 8.9 6.0 4.9 9.0 20.2 86.3 5.9 1.9 0.0 4.1 3.8 0.7 1.3 7.2 2.3 6.3 4.7 19.5 15.4 5.0 PON2 ENSG00000105854 "Paraoxonase 2" Q15165 7 95404862-95435329 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 258.9" "Cell type enhanced" "Detected in many" "Astrocytes: 341.5;Extravillous trophoblasts: 300.9;Skeletal myocytes: 284.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 33.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025430, HPA029193" Enhanced "Secreted to blood" NA NA 160000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025430: , HPA029193: AB_10602148" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-5)" "unprognostic (3.80e-1)" "unprognostic (4.14e-1)" "unprognostic (3.89e-2)" "unprognostic (3.77e-3)" "unprognostic (1.19e-3)" "unprognostic (9.87e-3)" "unprognostic (9.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (1.40e-1)" "unprognostic (6.43e-2)" "unprognostic (7.99e-3)" "unprognostic (2.56e-1)" 50.6 129.9 196.0 22.7 206.2 10.9 62.6 184.9 258.9 43.3 150.1 69.0 81.6 45.9 61.2 28.6 41.3 53.3 45.5 192.1 209.8 56.5 183.7 105.4 14.3 183.6 197.1 31.6 26.8 28.4 49.8 98.3 186.0 39.5 86.0 30.2 29.9 45.6 15.4 56.6 51.0 51.5 182.0 22.3 27.6 28.3 197.9 13.9 37.7 17.5 33.0 37.6 30.3 205.7 51.1 313.4 250.6 137.2 34.2 74.5 69.6 101.5 118.7 77.3 83.7 72.1 113.8 0.0 138.4 100.9 148.2 33.3 46.2 78.3 87.4 0.8 59.8 25.9 186.3 238.1 53.9 0.1 34.1 108.6 88.7 41.7 56.5 157.8 162.7 0.0 16.9 1.0 231.1 46.6 0.1 29.2 49.2 135.4 71.4 0.0 117.5 12.5 239.4 39.4 17.2 53.5 144.7 159.8 102.9 142.7 47.3 17.0 178.3 115.7 83.7 39.6 100.2 26.2 32.5 0.4 108.1 23.9 154.3 0.0 7.8 0.8 5.0 4.3 4.5 1.6 1.9 4.5 33.8 0.5 2.5 3.5 0.0 8.9 2.3 8.1 1.1 4.4 196.0 206.2 184.9 258.9 192.1 209.8 183.6 197.1 186.0 182.0 197.9 205.7 65.7 128.2 104.3 341.5 4.6 16.8 42.8 201.4 25.6 5.6 51.0 37.6 39.4 67.2 178.5 84.6 0.0 75.6 13.9 121.4 9.8 149.9 5.5 29.9 32.0 86.5 12.6 26.1 0.7 50.6 300.9 36.3 20.4 57.0 14.5 55.2 44.3 151.7 40.5 38.7 1.8 36.3 173.0 20.8 63.7 2.6 16.1 27.4 112.1 72.1 17.4 185.0 10.3 126.2 149.2 75.7 102.2 21.8 4.9 25.7 85.7 55.8 64.6 8.2 19.7 284.5 49.2 2.6 7.5 25.4 16.1 50.3 8.1 44.5 81.0 23.4 PPP1R3G ENSG00000219607 "Protein phosphatase 1 regulatory subunit 3G" B7ZBB8 6 5085341-5089487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.9;liver: 6.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 18.5;Glandular and luminal cells: 7.2" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.3;PC-3: 3.9;THP-1: 14.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056393 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA056393: AB_2683115" "unprognostic (1.99e-2)" "unprognostic (5.50e-3)" "unprognostic (2.10e-1)" "unprognostic (5.29e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (6.56e-3)" "unprognostic (8.64e-3)" "unprognostic (1.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.04e-2)" "unprognostic (3.71e-1)" "unprognostic (7.60e-2)" "unprognostic (1.33e-2)" "unprognostic (5.56e-2)" "unprognostic (3.17e-3)" "unprognostic (1.27e-1)" 2.3 3.0 2.3 0.3 2.1 0.1 1.4 1.5 2.7 2.1 0.9 2.0 0.2 1.2 1.0 1.8 1.0 0.3 5.9 2.0 1.8 0.6 6.2 0.3 0.5 2.3 2.3 0.8 0.1 0.3 0.2 0.7 1.9 1.2 0.5 0.2 0.6 1.4 0.5 1.2 0.5 0.5 1.6 2.8 0.6 0.2 2.2 0.2 0.3 0.2 0.4 2.8 2.1 1.7 0.0 0.2 0.1 0.0 1.6 1.0 0.0 0.3 0.4 0.2 0.3 0.0 0.3 0.0 3.3 0.6 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.3 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 3.9 0.1 0.0 0.0 0.4 0.4 0.0 0.0 0.5 0.0 0.0 0.3 0.0 14.6 0.0 0.0 0.0 0.8 0.5 2.0 1.7 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 2.3 2.1 1.5 2.7 2.0 1.8 2.3 2.3 1.9 1.6 2.2 1.7 4.2 0.0 0.0 0.0 0.4 0.5 0.5 0.4 0.0 0.5 0.2 0.1 18.5 0.0 0.1 3.7 0.0 0.8 0.0 1.3 0.0 0.3 0.0 1.2 2.0 1.9 1.2 0.0 0.0 0.0 0.4 3.7 0.0 7.2 0.0 1.4 2.9 0.0 4.5 0.0 0.0 0.9 0.0 4.0 4.7 0.2 0.9 1.8 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.6 1.8 3.0 1.8 0.4 0.0 2.1 0.2 0.2 0.0 2.0 2.5 0.1 0.9 0.2 0.3 0.8 0.2 0.5 1.4 1.2 PPP4R4 "CFAP14, KIAA1622, PP4R4" ENSG00000119698 "Protein phosphatase 4 regulatory subunit 4" Q6NUP7 14 94146128-94279734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 44.4;Cone photoreceptor cells: 75.0;Excitatory neurons: 63.1;Inhibitory neurons: 63.0;Spermatocytes: 33.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 6.7;RH-30: 19.4;T-47d: 23.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041866, HPA050321" Approved Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA041866: AB_10804120, HPA050321: AB_2681086" "unprognostic (2.65e-3)" "unprognostic (3.06e-1)" "unprognostic (9.07e-2)" "unprognostic (9.49e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (2.45e-1)" "unprognostic (1.25e-1)" "unprognostic (8.85e-2)" "unprognostic (6.91e-3)" "unprognostic (1.72e-2)" "unprognostic (8.95e-2)" "unprognostic (7.53e-2)" "unprognostic (3.35e-2)" "unprognostic (1.77e-1)" "unprognostic (6.24e-2)" 0.2 0.4 2.7 0.3 3.0 0.1 0.5 2.2 4.0 4.3 1.0 0.1 0.0 0.8 0.0 0.3 1.6 0.3 0.2 3.3 3.6 0.3 3.0 1.5 0.2 2.8 2.7 5.1 0.4 0.9 2.6 0.5 2.4 0.4 0.1 5.4 0.3 0.6 0.1 0.6 0.1 0.3 1.8 0.0 0.7 7.9 3.4 0.1 0.2 0.0 0.6 0.2 1.2 4.2 0.8 0.1 3.5 0.9 0.8 0.0 0.9 0.4 3.1 1.0 0.9 0.2 0.9 0.0 0.0 0.0 2.5 0.1 4.5 4.7 0.6 0.3 0.7 0.0 0.0 1.9 0.3 0.0 0.6 0.0 0.9 0.1 6.7 0.0 0.0 2.1 0.0 0.3 0.6 1.0 0.0 0.1 1.8 0.0 0.1 0.2 19.4 0.1 0.2 0.9 0.4 0.1 0.1 0.1 0.1 1.3 23.6 0.0 0.0 3.0 2.9 0.2 0.3 0.9 0.1 0.6 1.8 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 3.0 2.2 4.0 3.3 3.6 2.8 2.7 2.4 1.8 3.4 4.2 0.1 3.2 9.5 44.4 0.1 4.8 4.9 4.9 5.7 1.4 3.6 0.8 0.4 0.0 2.9 0.0 75.0 0.0 0.0 0.0 0.0 2.4 17.9 3.5 0.2 0.6 0.0 0.0 63.1 0.4 0.2 0.5 2.0 3.1 0.0 19.5 6.4 1.0 0.1 1.7 63.0 0.0 2.0 1.3 0.7 18.0 5.9 0.2 0.0 1.9 0.0 6.0 0.0 17.6 3.7 0.2 0.0 5.7 0.1 17.8 0.0 0.2 14.5 0.8 0.0 0.6 1.6 33.7 9.2 1.6 2.6 0.0 0.4 1.2 0.0 7.2 PROX1 ENSG00000117707 "Prospero homeobox 1" Q92786 1 213983181-214041510 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2;liver: 86.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 196.4;Hepatocytes: 285.9;Horizontal cells: 523.3;Paneth cells: 130.6" "Cancer enhanced" "Detected in many" "liver cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 31.4;RH-30: 15.9;SH-SY5Y: 77.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000842, HPA001030, HPA027298" Enhanced Nucleoplasm,Cytosol No No "Cluster 43: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Cytosol "HPA000842: AB_2666112, HPA001030: AB_2666177, HPA027298: " "unprognostic (3.07e-1)" "unprognostic (5.98e-2)" "unprognostic (1.06e-3)" "unprognostic (3.42e-1)" "unprognostic (7.71e-2)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (6.59e-2)" "unprognostic (1.85e-2)" "unprognostic (2.31e-1)" "unprognostic (3.29e-3)" "unprognostic (6.64e-2)" "unprognostic (4.56e-6)" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.71e-4)" "unprognostic (1.05e-1)" 1.6 10.0 11.0 1.4 21.4 0.0 1.8 24.6 18.2 1.0 0.0 2.6 2.1 1.1 1.2 0.6 2.2 1.9 15.7 23.1 12.4 4.7 86.8 1.2 2.8 18.7 17.3 7.4 15.5 0.1 4.0 0.4 13.9 0.5 2.7 21.2 0.3 0.4 3.6 0.7 2.6 0.8 10.6 7.1 2.1 5.4 30.0 0.2 7.6 2.1 0.7 1.0 0.7 38.2 0.0 0.0 0.6 0.0 0.3 0.3 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.7 0.0 0.0 0.3 0.2 2.3 0.0 0.1 0.0 1.0 0.6 0.0 31.4 0.0 0.0 0.2 0.3 0.1 0.0 0.2 0.1 3.5 2.3 5.7 0.0 0.4 0.0 0.4 0.0 1.7 2.0 1.3 0.0 15.9 2.5 0.2 0.5 2.3 77.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.2 0.7 0.2 0.9 0.0 0.0 0.0 0.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 21.4 24.6 18.2 23.1 12.4 18.7 17.3 13.9 10.6 30.0 38.2 14.3 0.0 2.3 1.3 1.9 5.9 1.1 0.3 5.7 196.4 4.8 4.7 105.9 102.9 1.3 9.2 2.1 0.0 0.1 3.2 15.6 34.7 52.7 0.1 1.0 36.5 66.9 5.3 2.9 2.7 0.1 8.7 8.6 0.3 0.0 9.3 11.0 285.9 0.9 523.3 66.8 16.5 12.2 4.4 6.6 10.4 1.2 2.2 10.6 8.4 0.0 36.0 0.0 27.2 114.0 3.4 130.6 1.2 0.1 3.9 3.3 0.4 0.9 11.7 0.0 113.6 3.7 2.9 0.4 0.4 4.5 0.0 1.9 29.6 10.5 0.9 PRSS53 POL3S ENSG00000151006 "Serine protease 53" Q2L4Q9 16 31083425-31089628 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2;liver: 9.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.3;Inhibitory neurons: 4.3;Oligodendrocytes: 4.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 4.8;U-87 MG: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034955, HPA034956" Uncertain "Secreted in other tissues" NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA034955: AB_2674380, HPA034956: AB_10696365" "unprognostic (3.13e-1)" "unprognostic (4.15e-1)" "unprognostic (3.88e-3)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.63e-2)" "unprognostic (1.04e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.63e-4)" "unprognostic (2.53e-12)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" 0.2 0.1 1.7 0.4 1.9 0.0 0.2 1.9 3.2 0.5 1.5 0.4 0.3 0.3 0.1 0.3 0.1 0.3 0.2 1.8 1.9 0.6 9.9 0.4 0.4 1.8 1.8 0.3 0.6 0.0 0.8 0.1 1.8 0.9 0.1 0.1 0.4 0.2 0.1 2.8 0.4 0.4 1.7 0.5 0.5 0.0 1.8 0.1 0.4 0.0 0.0 0.4 0.5 2.2 0.3 0.4 0.1 0.3 0.0 0.5 0.8 0.4 0.8 0.5 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.7 0.8 0.0 0.4 0.3 1.0 0.0 0.4 0.1 0.9 0.2 1.1 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 4.8 0.3 0.4 0.0 0.4 0.0 0.5 0.2 0.3 0.8 0.5 1.6 0.1 0.7 0.2 0.1 2.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.9 3.2 1.8 1.9 1.8 1.8 1.8 1.7 1.8 2.2 0.2 0.0 0.0 1.6 0.2 0.4 0.2 0.2 0.0 0.4 0.1 0.1 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.4 6.3 0.2 0.2 0.2 1.1 0.3 0.0 0.3 0.4 0.7 0.1 0.0 4.3 0.1 0.0 0.0 0.4 0.2 1.8 0.4 0.0 0.0 0.0 0.1 0.0 0.5 4.4 0.4 0.0 1.2 0.2 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.2 0.1 0.1 0.5 1.4 0.0 1.0 0.1 0.1 0.3 PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 405.6" "Group enriched" "Detected in some" 7 "Adipocytes: 161.4;Cardiomyocytes: 161.5;Hofbauer cells: 75.1;Smooth muscle cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 166.0" "Lineage enriched" "Detected in all" 11 "dendritic cells: 166.0" "Cell line enhanced" "Detected in many" "ASC diff: 947.9;HaCaT: 276.4;HUVEC TERT2: 436.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" 405.6 25.1 112.4 15.9 110.4 3.6 210.2 97.4 119.8 92.0 122.6 51.8 84.0 52.5 212.8 83.9 30.9 30.8 76.3 121.8 104.3 110.9 197.3 20.9 18.0 108.2 111.3 30.7 66.0 69.0 59.1 45.2 108.5 70.4 43.2 42.9 50.6 44.3 49.7 81.1 59.8 19.9 103.1 12.3 24.8 51.5 131.1 34.7 55.1 75.8 26.9 71.4 51.9 101.5 26.0 62.9 105.3 0.4 947.9 0.1 7.2 4.0 22.0 2.0 0.5 60.1 76.3 16.6 82.1 0.3 47.1 276.4 9.5 10.9 0.5 1.1 17.6 32.5 23.8 89.0 91.9 0.3 9.0 71.1 20.2 6.7 0.3 250.1 436.7 95.1 26.9 0.6 0.0 89.6 41.9 4.7 51.2 39.1 0.3 117.5 48.5 0.8 223.1 106.2 107.6 76.6 11.0 147.7 168.4 78.9 66.2 46.2 119.1 0.6 1.0 0.5 0.6 9.3 22.0 0.4 66.0 0.6 7.6 1.3 3.5 11.6 6.6 0.8 5.1 15.8 3.7 5.5 3.3 11.1 13.4 13.9 2.2 6.2 0.2 166.0 0.2 4.8 112.4 110.4 97.4 119.8 121.8 104.3 108.2 111.3 108.5 103.1 131.1 101.5 161.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.5 0.0 0.0 0.0 0.0 13.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 7.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.0 RABEPK "bA65N13.1, RAB9P40" ENSG00000136933 "Rab9 effector protein with kelch motifs" Q7Z6M1 9 125200542-125234161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023920, HPA067106" Supported Uncertain "Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA023920: AB_1856023, HPA067106: " "unprognostic (8.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.76e-2)" "unprognostic (1.58e-1)" "unprognostic (3.24e-2)" "unprognostic (2.70e-2)" "unprognostic (3.47e-2)" "unprognostic (3.47e-2)" "unprognostic (9.74e-2)" "unprognostic (4.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (8.25e-2)" "unprognostic (2.69e-1)" 17.4 15.0 27.9 14.6 30.0 11.6 16.4 27.3 32.5 16.4 25.5 17.7 11.5 15.1 16.9 16.1 15.4 10.6 14.5 27.2 28.9 14.7 58.7 12.2 13.9 28.5 28.6 13.1 14.3 14.9 19.7 11.9 28.6 14.0 14.8 15.7 10.7 13.0 15.0 16.6 11.4 16.4 27.9 12.8 13.5 16.1 29.7 14.8 11.7 13.6 13.8 17.3 15.3 29.2 24.6 57.2 21.3 39.2 34.0 41.0 39.4 33.3 32.5 38.7 30.6 68.6 24.0 73.5 29.1 45.5 38.2 64.8 54.2 41.3 38.0 42.6 45.1 32.6 52.7 105.2 30.4 62.3 21.7 30.0 49.0 55.3 59.1 23.5 41.8 45.3 71.8 20.6 37.5 66.8 44.5 42.2 43.0 96.7 51.2 62.0 41.2 81.5 31.4 18.8 50.3 25.5 34.3 23.8 39.2 21.1 48.3 26.5 36.1 26.7 26.3 61.8 58.8 27.4 65.5 51.2 34.3 40.1 40.7 27.8 19.6 23.2 24.0 16.6 22.1 23.8 34.4 23.6 21.6 20.6 38.2 28.2 27.9 23.0 17.3 20.6 38.8 23.8 27.9 30.0 27.3 32.5 27.2 28.9 28.5 28.6 28.6 27.9 29.7 29.2 9.9 0.0 11.3 13.1 9.9 14.5 17.2 23.4 28.5 12.1 9.1 11.2 9.5 10.0 8.5 5.5 8.4 36.1 7.8 8.7 25.4 13.9 85.2 8.6 11.9 13.1 2.4 13.5 25.2 13.3 32.2 17.4 10.2 8.5 5.1 10.4 10.0 54.8 20.9 13.5 24.0 11.9 10.2 7.7 10.8 19.2 16.1 7.4 8.8 6.5 31.6 12.0 14.4 9.0 17.2 10.0 4.9 18.8 16.8 24.9 9.2 23.2 8.0 17.1 0.0 13.5 13.5 7.0 11.2 20.0 12.9 12.7 13.0 13.1 15.9 15.6 RASGEF1B "FLJ31695, GPIG4" ENSG00000138670 "RasGEF domain family member 1B" Q0VAM2 4 81426393-82044244 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 118.7;granulocytes: 107.0;Langerhans cells: 282.6;Macrophages: 141.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 11.9;memory B-cell: 9.7;naive B-cell: 12.4;non-classical monocyte: 20.6;plasmacytoid DC: 28.0" "Group enriched" "Detected in all" 5 "B-cells: 12.4;dendritic cells: 28.0;monocytes: 20.6" "Cell line enhanced" "Detected in some" "CACO-2: 13.4;Daudi: 16.1;Karpas-707: 11.1;NTERA-2: 7.9;OE19: 9.2;SCLC-21H: 7.3;SuSa: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044574 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA044574: AB_10794292" "unprognostic (3.24e-1)" "prognostic favorable (6.40e-4)" "unprognostic (1.32e-1)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "prognostic favorable (1.49e-5)" "unprognostic (4.42e-2)" "unprognostic (6.31e-2)" "unprognostic (4.43e-1)" "unprognostic (4.85e-2)" "unprognostic (1.13e-2)" "unprognostic (3.88e-2)" "prognostic favorable (4.21e-6)" "unprognostic (4.19e-3)" "unprognostic (1.44e-2)" "unprognostic (3.19e-2)" "unprognostic (6.04e-2)" 13.8 6.4 8.9 11.0 20.1 32.5 8.3 12.8 9.4 8.8 17.0 6.5 13.6 3.5 12.3 11.3 8.0 12.0 4.3 8.0 9.3 9.4 41.8 19.8 10.7 37.6 12.5 2.5 2.8 5.4 7.5 13.0 39.0 4.2 7.1 12.5 9.9 2.1 2.9 24.3 13.9 5.9 10.0 11.2 14.7 2.4 18.4 14.2 3.4 2.3 9.8 6.0 5.3 20.2 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.1 0.0 0.0 0.0 13.4 0.3 16.1 0.0 0.0 0.1 0.3 1.1 0.1 0.0 0.1 2.5 1.4 1.0 0.6 0.5 0.3 0.7 0.2 0.6 0.0 0.5 0.1 0.0 2.8 0.2 11.1 0.0 0.6 5.5 0.5 7.9 9.2 3.6 1.6 0.1 6.4 0.5 0.2 7.3 0.1 0.0 2.3 0.1 7.3 1.1 0.0 0.0 0.0 0.5 0.5 0.1 0.1 0.0 5.1 1.2 0.2 0.2 0.8 3.0 0.4 1.9 11.9 2.1 9.7 1.6 1.6 2.7 12.4 2.8 2.7 1.1 3.8 20.6 28.0 0.5 1.2 8.9 20.1 12.8 9.4 8.0 9.3 37.6 12.5 39.0 10.0 18.4 20.2 9.6 28.9 15.9 1.3 118.7 58.9 7.9 4.4 23.9 11.7 22.7 13.2 9.1 15.7 11.1 14.7 37.5 33.2 71.2 13.2 13.7 3.1 0.5 44.5 4.8 10.8 26.8 0.0 3.6 4.0 2.4 9.1 30.1 38.0 107.0 0.6 102.1 45.9 39.5 3.3 2.8 12.8 16.2 64.2 282.6 1.5 0.9 141.4 62.2 10.3 2.9 1.0 2.1 26.7 25.5 3.0 9.6 1.9 33.5 10.2 9.2 12.9 34.0 4.9 0.0 5.9 17.7 0.8 3.2 10.4 56.7 11.2 56.3 0.5 8.1 11.5 RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 131.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 205.5;Ductal cells: 220.6;Exocrine glandular cells: 147.1;Pancreatic endocrine cells: 350.9" "Cancer enhanced" "Detected in many" "liver cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SK-BR-3: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Vesicles, Plasma membrane, Actin filaments" "HPA077800: AB_2686854" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "unprognostic (6.90e-2)" "unprognostic (1.32e-3)" "unprognostic (3.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.89e-1)" "unprognostic (8.38e-3)" "unprognostic (6.18e-2)" "unprognostic (6.60e-2)" "unprognostic (3.35e-3)" 9.6 0.8 24.4 2.6 26.9 1.8 5.6 18.9 40.6 1.6 15.4 4.8 2.4 3.9 1.0 3.1 2.7 14.5 7.3 26.8 20.4 4.4 131.8 37.9 1.0 21.4 23.6 1.2 2.8 2.4 8.0 1.2 21.9 6.5 1.9 1.7 3.9 0.8 1.0 1.6 2.6 2.4 19.9 0.8 23.4 0.9 22.1 2.4 15.4 0.6 2.3 14.0 2.7 23.2 1.1 7.9 3.8 2.0 0.8 0.0 0.6 0.0 0.4 1.2 1.3 4.9 1.7 6.0 1.4 0.0 0.4 0.1 3.1 0.3 0.7 1.8 1.9 0.8 0.0 3.0 0.4 1.8 1.1 0.0 0.2 0.6 0.8 0.0 2.0 3.9 0.2 6.0 0.0 10.2 0.9 0.5 8.9 13.6 0.5 1.9 0.4 2.6 1.1 1.5 0.0 1.0 0.2 67.7 0.3 9.1 6.9 0.4 0.2 0.0 0.7 0.0 0.9 2.9 5.4 10.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.4 26.9 18.9 40.6 26.8 20.4 21.4 23.6 21.9 19.9 22.1 23.2 28.9 28.9 205.5 5.9 8.5 11.5 8.4 14.1 9.1 2.5 37.5 25.4 3.8 18.6 27.5 1.8 8.4 1.1 9.0 21.7 0.0 220.6 0.4 4.5 2.0 87.3 31.5 2.7 10.6 147.1 0.7 10.5 55.5 12.6 15.2 0.8 6.1 10.9 1.2 0.0 2.7 11.4 18.3 0.8 24.1 0.0 0.0 6.6 14.2 1.0 6.4 3.0 0.0 7.1 1.0 350.9 42.2 0.4 6.5 19.5 11.1 1.7 7.7 3.6 0.0 5.8 16.7 0.8 1.6 4.3 10.5 1.5 9.9 0.6 5.4 8.6 RNF103 "hkf-1, KF1, ZFP103" ENSG00000239305 "Ring finger protein 103" O00237 2 86603398-86623866 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057922 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA057922: AB_2683555" "unprognostic (4.41e-1)" "unprognostic (1.56e-1)" "unprognostic (6.04e-2)" "unprognostic (3.26e-1)" "unprognostic (3.20e-2)" "unprognostic (1.79e-1)" "unprognostic (7.42e-2)" "unprognostic (8.37e-2)" "unprognostic (4.06e-1)" "unprognostic (1.13e-2)" "unprognostic (6.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.54e-3)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (3.67e-2)" "prognostic favorable (6.77e-5)" 14.6 15.3 25.7 9.0 28.8 13.6 20.9 35.8 31.6 15.9 22.6 21.9 18.7 23.7 45.4 14.0 16.9 19.4 37.7 24.8 25.1 15.3 54.5 11.3 8.1 26.8 27.2 16.0 24.7 25.2 15.6 15.6 25.7 23.3 16.5 10.3 18.7 17.7 21.4 14.3 23.0 21.0 27.2 10.5 22.6 15.4 26.7 8.1 10.2 19.1 10.0 14.4 13.9 30.6 9.6 12.9 6.4 9.9 28.6 18.3 10.3 13.6 20.6 6.8 9.2 7.5 16.1 15.9 15.9 20.4 24.8 11.5 8.7 10.7 10.2 13.4 11.7 9.1 5.4 16.7 27.1 3.0 13.0 26.9 21.8 10.1 12.6 24.3 20.7 7.4 3.3 9.3 19.0 11.9 7.0 8.0 2.9 19.0 9.0 4.3 27.5 9.4 25.1 14.9 10.2 10.4 16.0 35.2 14.0 8.0 13.5 7.4 23.6 13.2 6.3 13.4 8.2 32.3 11.5 10.7 10.5 5.1 6.5 4.5 0.5 7.2 0.7 0.7 1.0 0.9 1.1 1.6 1.1 1.0 1.2 0.9 1.0 2.3 0.4 0.8 2.5 0.6 25.7 28.8 35.8 31.6 24.8 25.1 26.8 27.2 25.7 27.2 26.7 30.6 22.6 9.6 14.5 0.0 16.6 48.3 35.5 13.9 33.6 15.8 45.9 31.1 40.0 31.5 22.1 20.2 4.2 13.6 15.7 72.4 1.9 17.6 16.8 20.4 17.9 22.4 31.8 16.4 0.0 28.4 7.8 27.6 44.4 30.0 18.4 19.9 22.9 68.9 9.6 18.5 0.0 45.9 12.2 14.1 29.5 9.3 25.4 19.8 10.6 0.0 8.0 17.2 2.1 0.0 0.0 33.9 41.5 23.0 41.1 45.0 56.1 12.9 33.6 9.5 6.6 40.3 25.7 27.5 12.6 32.6 44.2 40.9 19.5 9.0 24.3 48.6 RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072113 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 295.7;Kupffer cells: 393.7;Macrophages: 283.0;monocytes: 276.4;Oligodendrocytes: 514.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 261.6;classical monocyte: 513.2;eosinophil: 331.3;intermediate monocyte: 355.0;myeloid DC: 407.4;neutrophil: 890.5;non-classical monocyte: 328.7;plasmacytoid DC: 317.2" "Group enriched" "Detected in all" 11 "dendritic cells: 407.4;granulocytes: 890.5;monocytes: 513.2" "Cell line enhanced" "Detected in many" "HMC-1: 179.3" "Low region specificity" "Detected in all" HPA014499 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favorable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" 94.2 43.4 79.7 47.7 103.2 94.0 50.2 102.3 114.1 55.5 75.5 40.1 28.1 42.1 35.6 26.4 46.8 55.9 36.2 81.4 85.8 49.4 167.1 62.6 39.2 112.8 94.6 52.2 64.2 28.0 16.6 48.4 110.6 35.1 41.9 14.3 84.6 60.2 33.2 14.6 32.6 52.6 98.4 51.8 34.7 17.5 92.3 17.7 32.3 53.7 25.8 51.6 19.3 138.2 32.7 26.8 125.5 110.9 117.4 54.5 21.9 20.9 29.1 24.1 25.3 8.4 31.8 0.1 69.6 47.5 47.7 3.0 81.5 49.7 26.0 0.3 54.6 57.7 11.8 25.4 27.3 14.9 179.3 52.2 25.9 2.3 15.3 65.6 42.3 57.3 9.7 0.4 27.0 71.0 28.7 68.8 32.7 6.7 33.8 65.9 27.9 0.1 38.7 7.4 68.4 28.8 43.2 34.4 126.5 45.7 40.8 38.6 36.6 50.6 18.9 38.8 27.1 0.4 24.1 6.2 7.7 132.0 41.2 261.6 513.2 331.3 25.4 355.0 21.7 15.8 10.9 12.3 407.4 15.8 12.4 13.6 890.5 53.6 328.7 317.2 1.6 323.8 79.7 103.2 102.3 114.1 81.4 85.8 112.8 94.6 110.6 98.4 92.3 138.2 75.0 19.2 21.4 119.1 22.4 14.1 22.6 27.0 12.5 26.9 55.0 45.5 35.1 81.5 34.7 42.3 52.1 11.2 123.7 26.9 23.5 56.8 11.8 49.0 38.8 48.3 16.3 69.2 119.0 76.5 16.6 57.9 25.5 38.3 82.9 28.9 47.5 147.0 295.7 6.7 144.0 36.1 36.7 393.7 170.7 24.2 36.7 283.0 32.0 141.5 276.4 21.8 28.8 242.8 514.2 41.6 32.1 48.2 11.7 27.2 32.6 52.0 56.3 20.3 46.0 32.4 48.5 13.2 32.9 10.9 12.9 8.8 26.2 33.7 52.9 23.3 RTL4 "FLJ46608, Mar4, Mart4, SIRH11, ZCCHC16" ENSG00000187823 "Retrotransposon Gag like 4" Q6ZR62 X 112454500-112457112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "testis cancer: 1.4;thyroid cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003272 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane, Cytosol" "HPA003272: AB_2257414" "unprognostic (9.86e-2)" "unprognostic (2.04e-4)" "unprognostic (6.35e-2)" "unprognostic (5.33e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.8 1.1 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCARB2 "CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII" ENSG00000138760 "Scavenger receptor class B member 2" Q14108 4 76158737-76234536 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 12.5;classical monocyte: 14.1;intermediate monocyte: 26.0;myeloid DC: 8.2;non-classical monocyte: 24.9;plasmacytoid DC: 28.9" "Group enriched" "Detected in all" 5 "dendritic cells: 28.9;granulocytes: 12.5;monocytes: 26.0" "Cell line enhanced" "Detected in many" "ASC diff: 499.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015415, HPA018014" Supported Approved Cytosol NA NA 9200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB015415: AB_831511, HPA018014: AB_1852881" "prognostic unfavorable (2.82e-5)" "unprognostic (2.73e-2)" "unprognostic (4.09e-2)" "unprognostic (4.96e-2)" "unprognostic (4.17e-3)" "unprognostic (1.12e-3)" "unprognostic (2.08e-1)" "unprognostic (5.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.25e-2)" "unprognostic (4.11e-2)" "unprognostic (1.67e-1)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (6.88e-2)" "unprognostic (5.06e-2)" "unprognostic (3.89e-2)" 60.6 24.0 33.5 27.7 63.5 7.3 56.7 58.9 38.9 60.8 18.9 61.6 39.2 44.1 58.4 33.9 45.4 60.0 61.6 29.6 48.6 46.8 89.9 77.1 20.2 62.2 49.6 58.9 58.9 63.6 11.1 80.2 62.5 72.3 64.0 53.2 80.5 55.4 89.8 26.0 49.1 57.8 60.1 47.0 60.7 19.4 50.7 21.3 65.9 81.3 20.6 65.3 25.1 92.9 39.8 38.4 48.9 97.1 499.7 242.0 35.8 131.5 250.2 114.0 178.2 72.5 112.3 0.0 85.1 262.3 109.6 28.3 28.3 78.9 96.0 138.8 30.1 3.2 32.9 25.3 129.9 19.0 12.1 186.9 72.3 117.3 54.5 268.9 200.6 10.0 15.6 188.6 159.2 58.2 1.6 4.0 9.7 120.3 23.6 23.3 82.7 42.0 64.4 43.6 101.3 110.2 104.7 61.3 115.5 49.3 34.6 17.1 131.3 125.9 48.5 104.7 47.5 167.6 98.8 0.2 158.1 22.2 170.9 12.5 14.1 3.1 2.8 26.0 2.6 3.8 1.9 1.5 8.2 3.0 2.6 4.3 1.9 1.1 24.9 28.9 3.0 6.1 33.5 63.5 58.9 38.9 29.6 48.6 62.2 49.6 62.5 60.1 50.7 92.9 89.0 176.3 52.4 47.3 20.1 24.0 90.5 64.8 34.1 109.6 69.7 36.4 53.0 87.2 52.1 99.3 60.5 35.3 43.6 109.0 7.9 119.9 7.1 50.3 74.0 69.9 102.4 28.6 57.4 72.9 47.5 108.3 40.8 88.8 3.8 84.8 79.6 108.7 143.4 60.6 55.4 77.1 44.7 165.7 27.5 5.6 45.4 76.2 67.6 38.4 43.5 87.2 6.2 106.1 201.1 78.0 68.3 66.5 82.2 133.5 103.2 27.6 54.4 81.7 92.1 91.0 68.1 18.2 16.5 34.8 33.8 59.4 16.3 56.5 55.3 93.4 SCD "FADS5, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1233.7;brain: 839.9;liver: 583.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 389.6;Granulosa cells: 187.3;Hepatocytes: 840.3;Oligodendrocytes: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 2534.2;CAPAN-2: 1824.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: AB_2685154" "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (7.79e-5)" 1233.7 131.2 408.7 25.7 525.8 23.0 261.5 535.7 522.1 43.2 156.6 42.9 93.1 15.4 25.5 107.8 5.0 28.7 47.1 349.1 457.5 18.5 583.8 142.8 17.2 775.0 508.9 49.6 22.6 79.5 10.3 19.9 637.8 100.1 39.7 17.9 112.6 11.2 6.1 27.0 36.0 15.9 574.4 15.3 25.2 51.8 538.7 18.4 13.0 7.2 21.0 22.5 41.9 839.9 411.2 373.3 777.6 536.4 2534.2 1449.4 158.2 43.4 948.3 101.6 536.6 323.8 1824.4 173.3 33.7 102.2 461.8 716.4 433.7 1549.5 88.9 59.4 179.6 97.5 219.3 653.4 488.4 136.9 100.9 795.5 459.4 395.0 688.9 273.1 196.2 375.3 275.4 513.3 41.7 646.8 155.9 163.3 270.7 120.7 106.3 72.6 287.4 550.4 443.8 455.3 48.9 185.3 85.8 399.7 834.9 224.2 447.7 291.3 79.0 10.0 115.9 9.1 89.8 141.4 81.5 262.9 184.4 416.0 65.9 0.0 0.8 0.0 1.4 1.6 2.3 0.6 0.5 0.7 2.7 0.9 0.4 1.3 0.1 1.4 0.0 1.5 0.0 1.2 408.7 525.8 535.7 522.1 349.1 457.5 775.0 508.9 637.8 574.4 538.7 839.9 3.8 54.5 389.6 34.0 15.7 3.7 4.5 121.8 0.6 6.5 16.1 6.2 11.2 28.6 66.2 0.0 6.2 3.0 4.7 21.5 0.0 14.6 52.6 13.9 9.0 12.5 25.8 15.8 4.8 67.9 71.7 15.9 25.0 26.9 6.3 187.3 32.9 840.3 34.1 26.9 5.2 16.4 52.9 113.5 4.2 93.0 3.7 21.2 58.7 8.4 10.2 11.9 2.1 18.6 451.5 29.6 2.7 1.5 3.7 31.4 16.2 4.9 31.0 6.2 0.0 3.6 25.7 2.0 1.2 26.7 2.3 17.4 6.6 97.8 38.9 8.2 SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 515.9;Pancreatic endocrine cells: 476.4;Suprabasal keratinocytes: 472.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 512.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 320000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" 68.0 73.1 90.3 26.3 116.8 10.1 113.1 90.2 120.7 53.0 68.5 102.6 37.8 53.0 11.8 124.3 76.6 72.2 65.9 66.4 90.2 166.9 410.9 168.3 9.8 120.5 127.8 26.3 90.3 34.7 43.2 27.3 95.4 53.0 62.6 35.1 103.7 45.9 101.5 190.4 42.4 53.8 89.9 32.3 140.1 47.1 151.9 8.2 51.1 35.4 35.2 124.7 68.7 71.4 162.1 20.7 11.1 0.8 269.2 164.3 474.4 201.5 273.0 222.9 158.6 242.7 400.0 0.2 88.1 255.4 224.5 203.1 8.2 512.2 269.0 46.7 7.4 4.9 15.8 95.8 292.4 1.0 8.2 223.1 336.5 92.4 223.2 123.3 29.9 3.7 8.2 0.5 130.5 159.9 0.2 14.2 20.4 139.9 63.1 0.3 99.7 0.6 367.7 211.7 4.3 15.6 277.2 169.4 51.4 125.2 123.1 9.7 56.4 169.4 141.4 17.3 131.8 8.5 6.7 0.7 266.2 16.4 103.2 1.5 1.6 0.4 0.7 0.6 2.1 0.3 2.0 0.8 1.5 0.3 0.4 0.5 0.8 0.7 0.6 1.4 4.4 0.7 90.3 116.8 90.2 120.7 66.4 90.2 120.5 127.8 95.4 89.9 151.9 71.4 21.9 291.7 391.2 106.7 3.8 373.7 322.2 352.8 75.1 14.5 208.8 90.6 59.3 245.9 218.4 189.4 12.5 38.9 7.8 174.3 64.6 296.0 1.2 116.6 20.8 16.0 55.1 7.4 0.2 515.9 230.0 43.0 170.7 179.0 13.9 10.8 11.4 260.6 18.8 0.0 0.3 131.9 160.7 19.3 106.0 3.8 4.1 39.5 76.5 5.6 33.0 10.0 0.0 3.5 1.8 476.4 121.7 5.3 2.1 284.2 59.0 153.8 178.6 23.6 0.0 34.9 33.5 1.8 2.5 170.9 472.8 67.5 16.8 3.2 90.7 423.9 SDSL "cSDH, SDS-RS1" ENSG00000139410 "Serine dehydratase like" Q96GA7 12 113422380-113438276 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2;Hepatocytes: 116.7;Hofbauer cells: 95.7;monocytes: 103.1;Proximal tubular cells: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 8.7;intermediate monocyte: 10.0;myeloid DC: 18.5;plasmacytoid DC: 17.8" "Group enriched" "Detected in many" 6 "dendritic cells: 18.5;monocytes: 10.0" "Cell line enhanced" "Detected in many" "HMC-1: 51.4;MCF7: 90.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005740 Approved Approved Cytosol NA NA 48000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA005740: AB_10601486" "unprognostic (1.34e-1)" "unprognostic (8.33e-2)" "unprognostic (3.62e-2)" "unprognostic (3.54e-2)" "unprognostic (2.24e-2)" "unprognostic (6.17e-3)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (8.22e-2)" "unprognostic (2.00e-2)" "prognostic favorable (8.58e-4)" "unprognostic (2.93e-1)" "prognostic favorable (3.09e-5)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (7.33e-2)" 4.5 33.1 12.7 7.1 14.2 3.2 4.9 16.4 15.2 4.6 10.8 12.2 16.8 4.8 9.9 2.5 7.9 7.7 12.8 11.8 16.1 34.9 104.6 5.7 3.4 18.7 16.2 4.6 18.7 12.4 15.5 4.4 16.0 8.5 8.5 2.4 4.8 6.6 3.0 1.3 12.2 5.2 15.8 5.8 9.1 10.6 16.4 1.5 23.9 1.3 1.7 6.2 1.4 17.4 8.5 33.3 4.7 14.1 0.9 1.9 3.2 4.8 1.2 5.2 4.4 14.1 8.7 0.4 24.2 8.1 14.4 8.6 2.2 11.4 1.7 20.5 8.4 22.1 8.5 6.3 27.5 2.8 51.4 4.4 16.0 12.8 18.8 5.9 8.0 0.0 17.3 6.6 6.5 90.2 0.1 10.2 4.6 9.6 14.6 0.0 7.0 16.5 13.6 10.6 1.5 0.5 20.6 23.6 18.4 4.2 28.6 24.8 7.2 6.2 11.9 26.9 4.2 1.4 1.4 0.3 26.3 8.4 7.8 0.2 8.7 0.0 0.0 10.0 0.0 2.2 0.0 0.0 18.5 0.1 0.0 0.0 0.4 1.8 1.3 17.8 0.3 2.5 12.7 14.2 16.4 15.2 11.8 16.1 18.7 16.2 16.0 15.8 16.4 17.4 1.2 0.0 5.1 2.0 3.1 0.9 2.2 7.0 0.0 0.5 15.3 10.2 18.2 27.1 6.3 29.5 2.1 16.3 4.9 43.7 78.2 36.1 0.5 14.8 7.7 4.0 31.8 10.1 1.3 20.1 3.0 4.5 12.8 10.1 43.8 15.3 6.4 116.7 95.7 3.3 0.6 36.4 4.1 18.1 8.4 1.5 2.8 36.9 3.6 1.9 103.1 33.5 0.0 1.5 2.0 16.2 63.2 5.7 0.0 6.1 63.2 115.7 3.8 2.6 0.0 0.2 7.3 0.2 0.4 1.1 0.6 7.3 1.9 29.5 31.0 5.9 SEC14L2 "C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1" ENSG00000100003 "SEC14 like lipid binding 2" O76054 22 30396941-30425303 "Predicted intracellular proteins" "Transcription, Transcription regulation, Transport" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 86.0;liver: 243.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 146.3;Muller glia cells: 112.6;Pancreatic endocrine cells: 115.2;Proximal enterocytes: 52.8;Rod photoreceptor cells: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.7;naive CD8 T-cell: 2.7" "Lineage enriched" "Detected in single" 7 "T-cells: 3.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 93.9;hTCEpi: 47.3;hTERT-RPE1: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064466 Approved Supported Nucleoplasm,Cytosol NA NA 580000 "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA064466: AB_2685270" "prognostic favorable (3.05e-4)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (5.59e-3)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.63e-6)" "unprognostic (1.25e-3)" "unprognostic (3.76e-3)" "unprognostic (2.23e-1)" "unprognostic (2.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.63e-3)" "unprognostic (1.17e-3)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-3)" "unprognostic (2.01e-1)" 2.8 1.4 33.1 2.6 43.3 4.1 44.4 35.8 37.1 6.0 35.4 3.4 21.6 3.4 86.0 20.6 3.1 7.4 2.4 34.3 39.7 8.0 243.8 2.7 3.1 45.4 39.5 2.6 2.6 11.0 11.1 1.5 33.2 52.3 1.3 64.2 9.3 13.7 0.7 7.0 24.3 3.4 30.4 1.1 5.9 1.3 41.4 4.2 9.0 0.5 4.5 3.2 7.7 32.2 24.8 5.5 5.0 6.4 6.5 16.8 0.4 18.0 15.5 12.0 13.1 1.6 15.9 0.5 5.6 22.7 20.5 20.0 3.0 93.9 13.8 2.2 4.1 0.4 5.4 8.0 9.2 0.0 7.1 11.5 47.3 11.5 20.8 55.5 29.7 4.2 0.1 0.5 22.2 4.0 3.0 0.5 0.1 13.9 7.6 1.2 8.0 0.6 20.7 7.8 2.8 3.1 13.3 3.2 11.2 0.6 14.7 0.5 41.2 15.8 10.4 6.8 12.7 0.3 0.2 0.8 32.4 0.1 12.6 0.0 0.1 0.2 0.5 0.1 0.2 0.4 1.4 0.3 0.0 0.3 3.7 2.7 0.3 0.0 0.0 0.5 0.7 0.8 33.1 43.3 35.8 37.1 34.3 39.7 45.4 39.5 33.2 30.4 41.4 32.2 1.1 3.2 5.8 33.6 1.1 4.1 18.0 25.2 6.8 9.2 36.5 21.7 1.2 12.8 10.3 0.0 16.7 4.2 3.2 0.6 5.9 22.9 8.3 2.9 2.3 2.4 1.2 17.2 9.8 18.7 0.3 5.1 5.6 5.8 5.7 0.7 7.1 146.3 0.5 13.5 6.7 2.0 4.1 4.4 0.4 10.7 1.2 2.6 7.2 1.9 0.2 112.6 0.0 21.6 13.2 115.2 0.0 0.7 2.5 15.3 52.8 8.7 3.9 56.0 0.0 2.8 4.0 0.6 1.2 5.6 2.0 3.0 7.4 0.1 2.1 7.8 SERINC5 "C5orf12, TPO1" ENSG00000164300 "Serine incorporator 5" Q86VE9 5 80111651-80256048 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 223.2;Oligodendrocytes: 222.5;Urothelial cells: 254.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037898, HPA037899" Supported Supported "Vesicles,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "Vesicles, Centrosome" "HPA037898: AB_10673649, HPA037899: AB_2675727" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.98e-3)" "unprognostic (1.08e-2)" "unprognostic (5.05e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-2)" "unprognostic (8.00e-2)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" "unprognostic (7.71e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-2)" "unprognostic (4.81e-2)" "unprognostic (8.09e-2)" "unprognostic (4.93e-2)" "unprognostic (9.17e-2)" 12.9 34.8 19.2 9.8 31.0 6.3 11.8 27.2 20.7 16.4 17.4 28.3 9.2 9.2 21.1 17.6 16.2 14.2 5.3 18.0 22.7 6.2 45.4 14.1 8.2 26.5 27.6 15.1 7.6 7.1 4.1 16.5 26.8 33.7 29.4 16.3 13.3 7.0 2.7 19.1 9.7 7.6 22.2 4.8 16.6 29.2 28.0 7.9 5.8 2.9 11.4 17.8 11.3 44.4 11.3 19.7 6.6 4.2 8.9 9.5 19.6 9.0 6.0 3.9 4.0 40.0 56.7 1.7 9.0 11.7 9.2 31.7 8.9 23.9 5.6 1.6 4.8 1.4 2.2 21.7 3.3 1.3 4.1 10.8 13.1 10.2 26.0 11.0 7.3 54.0 3.6 9.4 10.4 19.4 22.8 5.5 9.3 15.8 6.8 26.9 5.8 3.0 11.5 54.4 0.4 6.3 8.0 18.5 35.4 33.5 8.2 6.9 8.0 11.3 3.2 11.6 11.3 7.1 3.5 28.1 21.0 3.9 46.9 10.4 9.1 6.7 2.1 4.9 1.6 0.8 18.7 5.7 5.8 1.1 23.3 14.1 5.2 0.6 1.5 1.4 6.6 7.5 19.2 31.0 27.2 20.7 18.0 22.7 26.5 27.6 26.8 22.2 28.0 44.4 48.5 60.9 30.2 46.0 10.5 6.4 56.8 5.6 19.9 3.6 27.7 14.1 8.2 31.5 18.3 16.5 0.0 16.1 12.9 127.4 9.8 26.5 1.7 82.0 29.6 24.5 60.1 24.8 20.9 19.5 25.7 24.9 40.2 157.0 8.2 27.6 35.3 82.7 21.8 3.3 78.3 60.0 4.1 29.2 27.8 7.6 18.3 38.4 5.4 66.5 44.8 65.1 1.0 223.2 222.5 35.4 56.4 39.9 8.7 148.2 27.7 5.1 4.3 5.3 32.9 7.5 17.4 3.1 12.8 44.4 9.8 129.2 37.7 15.2 85.9 254.2 SHFL "C19orf66, FLJ11286, IRAV, RyDEN, SFL" ENSG00000130813 "Shiftless antiviral inhibitor of ribosomal frameshifting" Q9NUL5 19 10086122-10093252 "Predicted intracellular proteins" "Antiviral defense" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 75.7" "Cell type enhanced" "Detected in some" "Adipocytes: 23.3;dendritic cells: 21.7;Fibroblasts: 6.8;Hofbauer cells: 32.6;Plasma cells: 9.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 71.8;BJ hTERT+ SV40 Large T+ RasG12V: 81.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042001 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA042001: AB_10794167" "prognostic favorable (4.04e-4)" "unprognostic (1.21e-2)" "unprognostic (2.39e-3)" "unprognostic (2.03e-1)" "unprognostic (2.19e-2)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (6.57e-2)" "unprognostic (4.22e-3)" "unprognostic (2.34e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (8.96e-11)" "unprognostic (5.92e-2)" "unprognostic (1.81e-1)" "unprognostic (4.41e-3)" "prognostic favorable (1.35e-4)" 12.8 18.5 27.1 14.2 27.4 15.7 12.2 26.3 30.1 17.0 24.4 12.8 14.8 15.8 16.5 8.6 17.6 18.1 8.2 27.2 28.5 14.0 75.7 16.8 22.8 27.3 27.0 18.9 9.9 16.7 14.1 12.7 27.2 11.9 9.9 15.0 16.3 19.1 4.4 9.5 18.4 15.4 28.8 19.9 11.0 4.3 29.5 20.4 12.2 6.9 16.6 14.7 12.3 28.1 9.4 3.8 5.0 3.9 20.3 23.6 1.4 7.6 46.3 71.8 81.2 0.4 7.4 4.8 2.1 24.0 25.7 3.9 3.9 20.7 12.0 30.4 0.4 15.5 3.0 10.6 32.6 4.7 9.7 34.3 11.7 11.5 4.1 27.1 22.9 20.6 1.8 20.2 15.0 6.5 20.1 13.3 1.1 7.0 5.5 16.2 0.0 8.0 14.8 13.0 0.7 3.5 12.9 1.3 42.2 0.9 1.2 12.9 14.8 6.0 3.0 9.6 1.6 24.1 7.2 1.2 16.8 6.0 12.1 16.4 12.8 18.2 23.3 11.7 31.1 13.0 19.5 25.4 10.2 10.1 16.3 17.7 16.4 32.7 20.3 2.0 21.7 15.5 27.1 27.4 26.3 30.1 27.2 28.5 27.3 27.0 27.2 28.8 29.5 28.1 23.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 5.4 21.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 6.8 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 2.6 3.3 0.0 0.0 0.0 SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 116.9;prostate: 73.9;urinary bladder: 62.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.0;Hepatocytes: 79.2;Proximal enterocytes: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA037690: AB_2675613, HPA037691: AB_2675614" "unprognostic (2.50e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.45e-2)" "unprognostic (3.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.33e-2)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.22e-2)" "unprognostic (2.91e-2)" "unprognostic (2.88e-2)" "unprognostic (2.26e-3)" 9.3 2.4 25.2 2.6 32.0 0.2 8.2 28.9 26.9 12.6 10.4 20.5 6.1 11.3 2.1 5.1 8.4 6.7 7.6 20.2 23.6 10.7 116.9 10.5 0.6 42.1 30.9 5.6 16.2 4.9 6.8 11.8 33.3 73.9 11.1 3.4 7.0 15.2 1.7 1.5 16.6 3.9 26.1 2.3 10.9 1.7 31.2 0.6 6.9 1.3 0.5 62.4 9.3 55.7 8.6 5.1 0.9 0.8 1.4 4.0 9.0 9.1 7.7 7.0 7.8 11.2 5.7 1.5 12.5 4.9 3.8 0.8 3.1 5.7 4.3 9.5 11.0 0.3 8.7 10.5 4.1 0.7 3.1 1.7 3.0 4.9 3.0 4.8 4.8 0.1 7.3 8.1 6.1 4.8 0.2 4.0 1.4 6.7 8.1 0.5 0.0 0.8 1.2 24.4 5.7 1.5 8.8 0.7 4.9 4.5 5.2 2.9 4.5 8.1 11.7 1.1 11.5 9.2 6.8 0.1 7.9 0.0 2.5 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 25.2 32.0 28.9 26.9 20.2 23.6 42.1 30.9 33.3 26.1 31.2 55.7 18.3 25.6 22.3 18.9 1.8 1.3 15.4 2.3 3.4 3.7 9.3 5.5 2.2 30.0 11.3 9.2 10.4 6.8 1.0 135.0 1.9 6.0 0.9 7.1 17.3 18.1 22.8 2.7 3.0 10.7 4.8 6.1 33.6 15.1 8.2 9.0 25.0 79.2 6.6 16.8 1.0 28.6 0.0 8.7 5.5 1.1 4.7 4.6 0.0 23.4 8.1 19.9 3.1 6.6 37.5 7.1 53.6 4.9 3.6 31.6 65.5 3.5 9.1 13.3 26.3 2.8 5.1 7.6 5.1 1.8 2.0 2.9 2.5 1.4 35.5 17.3 SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA036243: AB_2675019, HPA044580: AB_10962723" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.23e-2)" "unprognostic (9.13e-3)" "unprognostic (1.92e-1)" "unprognostic (4.13e-2)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (8.37e-3)" "unprognostic (2.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.06e-2)" "unprognostic (1.44e-3)" 10.3 3.6 5.1 2.1 5.3 3.7 4.1 7.1 7.9 2.1 0.0 3.2 3.8 3.5 3.2 2.6 2.1 2.3 2.8 5.0 5.6 5.8 11.4 3.1 2.7 2.7 3.5 2.3 5.1 3.5 2.6 2.8 3.4 8.2 2.8 4.7 4.5 2.8 4.9 3.0 3.8 2.6 2.2 2.4 4.5 1.5 7.0 2.0 3.5 2.3 2.0 2.7 2.1 6.1 2.8 1.1 3.2 4.4 4.2 5.0 3.4 3.8 4.2 2.4 2.6 6.6 1.9 3.0 2.7 7.6 1.3 1.6 10.2 1.9 6.1 2.2 6.3 1.6 3.5 2.9 5.1 5.2 3.4 4.3 4.9 4.6 6.4 3.6 2.0 2.6 1.8 4.8 5.2 2.6 2.9 3.7 0.7 0.8 14.8 1.6 2.3 1.0 6.8 9.2 2.2 1.8 5.4 5.2 4.4 2.2 2.9 2.1 8.9 3.6 4.8 6.1 4.5 4.9 2.8 4.9 3.5 4.2 1.6 1.4 0.7 0.7 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.8 0.4 0.6 1.3 0.6 0.4 0.8 0.4 0.3 5.1 5.3 7.1 7.9 5.0 5.6 2.7 3.5 3.4 2.2 7.0 6.1 9.6 44.8 20.7 23.5 9.9 6.4 6.3 4.9 4.6 19.2 11.0 6.7 10.4 12.8 7.4 12.9 39.6 19.0 12.4 12.9 11.7 8.1 9.9 9.6 9.3 7.8 15.0 9.9 44.0 19.2 32.3 8.8 20.9 14.1 8.2 6.1 13.9 37.7 10.6 20.2 53.7 9.4 8.2 10.3 6.5 13.0 3.1 7.9 1.8 13.1 8.2 9.5 15.5 29.7 48.0 14.4 7.8 7.9 16.4 13.5 17.7 21.4 9.9 31.2 0.0 13.4 11.3 4.5 2.5 10.5 6.8 59.8 9.4 9.4 9.0 10.6 SLC38A3 "G17, SN1" ENSG00000188338 "Solute carrier family 38 member 3" Q99624 3 50205246-50221486 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "liver: 331.6;retina: 172.9" "Group enriched" "Detected in many" 6 "Bipolar cells: 88.3;Cone photoreceptor cells: 187.7;Hepatocytes: 114.6;Muller glia cells: 80.1;Rod photoreceptor cells: 124.0" "Cancer enriched" "Detected in many" 9 "liver cancer: 140.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.9" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.9" "Group enriched" "Detected in some" 5 "Hep G2: 49.8;SCLC-21H: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031871 Approved Microtubules,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol Microtubules "HPA031871: AB_2674080" "unprognostic (2.14e-1)" "unprognostic (2.10e-1)" "unprognostic (8.60e-2)" "unprognostic (6.19e-4)" "unprognostic (7.37e-2)" "unprognostic (9.61e-2)" "unprognostic (2.34e-2)" "unprognostic (2.30e-2)" "unprognostic (4.68e-3)" "unprognostic (1.46e-1)" "unprognostic (2.06e-1)" "unprognostic (5.71e-2)" "unprognostic (1.23e-3)" "unprognostic (1.90e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.96e-1)" 1.4 0.1 30.8 0.1 33.8 1.0 1.4 38.7 42.1 0.5 27.4 0.2 1.3 0.3 0.4 1.1 0.6 0.4 5.6 29.8 30.8 5.1 331.6 0.2 0.5 35.8 40.5 6.3 37.2 7.9 4.6 1.2 34.9 0.5 0.1 172.9 1.8 0.1 35.8 0.8 0.6 0.2 32.4 0.2 1.9 1.9 36.4 0.0 1.3 35.8 0.3 0.1 0.4 35.0 0.0 0.0 1.2 7.0 0.1 0.0 1.7 0.0 0.0 1.3 0.6 4.1 0.0 0.1 1.1 0.0 0.3 0.0 1.9 0.0 0.9 0.1 0.6 0.0 1.0 49.8 0.1 0.5 0.0 0.1 0.0 0.1 0.0 5.6 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.5 0.5 0.0 0.2 0.2 15.4 1.3 0.7 0.2 0.0 2.1 2.0 0.3 0.0 0.2 1.2 0.0 1.0 0.3 0.0 0.1 0.2 0.3 0.1 2.9 0.2 0.3 0.2 0.0 0.1 0.3 0.1 0.1 0.0 0.2 0.2 0.2 0.8 0.4 0.0 0.2 0.1 0.1 30.8 33.8 38.7 42.1 29.8 30.8 35.8 40.5 34.9 32.4 36.4 35.0 0.3 0.0 0.0 17.6 0.4 0.0 0.1 0.0 0.6 88.3 3.2 1.7 3.3 17.2 0.0 0.0 187.7 0.2 0.0 0.0 0.0 1.8 0.3 0.4 0.0 3.9 3.5 2.7 0.2 2.2 0.1 0.2 0.0 0.5 0.0 0.1 2.2 114.6 0.1 8.4 0.6 0.2 0.0 2.6 0.0 0.0 2.1 0.1 0.0 7.5 0.6 80.1 0.0 4.5 3.7 0.6 0.0 0.4 0.0 0.0 0.0 4.2 0.0 124.0 0.0 0.6 0.3 2.9 3.3 0.9 0.0 1.4 0.2 0.0 0.2 0.0 SLC5A6 SMVT ENSG00000138074 "Solute carrier family 5 member 6" Q9Y289 2 27199587-27212958 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 119.1;Extravillous trophoblasts: 111.7;Hepatocytes: 67.7;Syncytiotrophoblasts: 227.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 310.9;SK-BR-3: 337.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036958 Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA036958: AB_10672343" "unprognostic (5.85e-2)" "unprognostic (8.32e-3)" "unprognostic (1.38e-1)" "unprognostic (2.61e-3)" "unprognostic (9.38e-2)" "unprognostic (7.14e-2)" "unprognostic (3.20e-3)" "unprognostic (7.92e-2)" "unprognostic (6.96e-2)" "unprognostic (9.80e-2)" "unprognostic (2.05e-2)" "unprognostic (7.46e-2)" "prognostic unfavorable (3.60e-7)" "unprognostic (2.40e-3)" "unprognostic (1.20e-2)" "unprognostic (4.56e-3)" "unprognostic (4.18e-2)" 42.4 8.6 27.5 14.2 25.2 18.1 31.5 24.0 30.6 9.4 46.2 13.0 20.9 14.3 67.4 10.9 11.5 7.5 7.7 23.4 23.9 8.5 104.0 7.9 13.8 24.0 24.4 10.2 11.6 9.8 8.0 39.1 25.9 9.3 12.7 6.4 12.5 11.1 17.0 10.0 15.3 9.7 23.9 9.1 10.1 23.4 30.6 11.6 8.0 8.8 26.5 11.3 8.8 21.9 78.9 79.6 49.9 66.1 45.4 16.5 310.9 28.1 19.1 41.8 28.7 118.8 27.0 54.2 41.3 15.4 44.7 42.8 108.3 32.4 29.1 42.2 63.5 96.6 34.9 184.4 53.8 125.1 47.8 57.1 27.1 51.4 39.7 11.1 38.2 43.3 143.6 21.1 27.0 161.0 42.7 60.4 144.8 90.1 29.0 70.7 58.7 78.2 24.0 74.5 42.0 61.7 30.3 337.1 40.1 48.6 74.9 26.0 17.5 45.3 62.5 27.9 76.1 35.7 88.6 84.7 24.5 86.1 65.2 0.1 5.9 1.8 7.4 6.6 8.9 5.8 7.0 7.0 8.7 5.3 7.1 8.6 0.3 6.3 8.9 8.9 7.6 5.8 27.5 25.2 24.0 30.6 23.4 23.9 24.0 24.4 25.9 23.9 30.6 21.9 2.5 0.0 4.4 7.8 13.4 8.0 8.6 3.8 7.4 5.3 41.9 31.9 6.8 8.6 3.1 7.3 4.2 119.1 12.5 6.7 1.9 9.8 15.1 3.9 7.4 6.2 5.4 12.6 7.2 8.2 111.7 6.0 5.6 6.9 0.0 18.1 7.1 67.7 21.8 11.8 9.0 9.2 4.1 9.1 6.0 32.0 7.2 6.6 0.0 29.0 47.9 2.5 6.2 6.6 5.0 7.0 4.3 13.9 10.0 14.1 11.7 3.9 2.9 3.1 13.1 5.5 5.2 35.1 21.5 7.6 6.3 227.9 8.6 9.4 15.2 7.8 SLC6A1 "GABATHG, GABATR, GAT1" ENSG00000157103 "Solute carrier family 6 member 1" P30531 3 10992186-11039247 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.3;liver: 87.3;retina: 37.0" "Group enriched" "Detected in some" 4 "Astrocytes: 221.0;Inhibitory neurons: 332.3;Microglial cells: 108.7;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 107.9" "Group enriched" "Detected in some" 16 "glioma: 16.1;liver cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013341, CAB022293" Enhanced NA NA "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022293: , HPA013341: AB_1849509" "unprognostic (1.66e-3)" "unprognostic (1.30e-3)" "unprognostic (4.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.53e-1)" "unprognostic (2.53e-1)" "prognostic favorable (3.20e-4)" "unprognostic (1.05e-1)" "unprognostic (4.27e-2)" "unprognostic (8.26e-2)" "unprognostic (2.90e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (5.05e-6)" "unprognostic (7.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.35e-1)" "unprognostic (5.34e-2)" 1.9 0.8 51.5 0.4 56.0 2.2 1.0 45.4 67.1 3.3 0.0 1.1 0.4 1.2 2.9 9.1 1.2 1.2 4.1 35.8 53.6 2.9 87.3 2.0 0.5 39.4 63.5 2.1 0.3 15.9 3.6 0.8 34.8 2.4 0.5 37.0 0.4 4.0 2.7 1.7 0.9 0.5 43.0 0.7 0.5 4.1 71.3 17.6 0.7 0.8 0.4 0.9 2.6 39.4 0.2 0.2 0.5 0.3 0.4 0.1 0.3 0.2 0.0 0.2 0.3 0.4 0.3 0.4 0.1 0.1 0.5 0.4 0.6 0.2 0.2 0.0 0.5 0.4 1.6 0.8 0.2 0.6 0.6 0.3 0.0 0.0 0.3 0.1 0.1 0.5 0.3 1.0 0.0 0.3 0.2 0.5 0.2 0.3 0.4 0.3 0.0 0.0 0.1 0.5 0.2 0.0 0.2 0.2 0.0 0.3 0.3 0.3 0.1 0.2 0.1 0.2 0.2 0.3 0.1 0.3 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 51.5 56.0 45.4 67.1 35.8 53.6 39.4 63.5 34.8 43.0 71.3 39.4 0.3 0.0 0.5 221.0 0.0 0.3 0.0 0.0 6.2 26.6 0.1 0.0 2.1 14.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.1 2.6 0.0 0.0 3.7 0.0 0.0 1.4 0.0 0.0 2.5 0.2 0.0 25.2 0.0 0.0 332.3 0.0 0.0 0.8 0.0 1.6 5.6 0.2 0.0 108.7 0.0 36.6 0.0 130.2 107.9 0.0 0.0 10.1 0.0 0.0 0.0 0.2 0.0 3.7 13.1 9.4 6.8 3.8 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 SLC6A12 BGT-1 ENSG00000111181 "Solute carrier family 6 member 12" P48065 12 190077-214570 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 35.2;kidney: 36.0;liver: 81.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 46.0;Hepatocytes: 22.7;monocytes: 10.7" "Cancer enhanced" "Detected in many" "liver cancer: 8.8;renal cancer: 11.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 50 "classical monocyte: 5.7;intermediate monocyte: 5.7;myeloid DC: 2.4;neutrophil: 3.0;non-classical monocyte: 7.9" "Group enriched" "Detected in many" 45 "dendritic cells: 2.4;granulocytes: 3.0;monocytes: 7.9" "Cell line enhanced" "Detected in some" "Hep G2: 7.2;RPTEC TERT1: 13.8;SuSa: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034973 Approved Approved Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034973: AB_10610427" "unprognostic (3.48e-1)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.70e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-2)" "unprognostic (8.30e-2)" "unprognostic (6.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.85e-2)" "unprognostic (3.68e-1)" "prognostic favorable (2.70e-6)" "unprognostic (2.30e-1)" "unprognostic (4.92e-4)" "unprognostic (3.35e-1)" "unprognostic (4.31e-4)" 0.2 0.4 22.6 1.1 23.3 0.1 0.4 18.0 35.2 0.8 12.4 0.7 4.5 1.1 6.8 0.0 3.4 1.0 0.3 18.5 21.5 36.0 81.5 2.4 0.5 19.8 25.2 0.3 1.6 0.4 0.8 0.5 20.9 0.1 1.8 0.5 0.1 0.0 0.1 0.2 0.8 0.9 16.5 0.5 2.4 1.6 22.4 0.3 6.3 0.0 0.3 0.4 0.3 17.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.8 0.1 0.0 0.4 0.0 0.0 0.1 2.9 0.2 0.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 3.0 0.0 7.9 0.0 0.0 1.9 22.6 23.3 18.0 35.2 18.5 21.5 19.8 25.2 20.9 16.5 22.4 17.7 0.1 0.0 0.5 4.2 0.6 0.1 0.0 0.0 0.0 0.5 0.9 0.6 0.7 0.0 0.1 46.0 0.0 0.0 0.0 1.6 1.9 0.0 4.6 3.5 1.7 0.2 0.0 0.0 0.4 0.4 0.0 0.6 2.0 8.8 0.0 0.1 0.7 22.7 2.4 0.0 0.3 1.7 0.0 1.9 2.5 6.2 0.6 1.6 0.0 8.4 10.7 5.2 0.0 0.5 9.2 0.0 1.2 0.0 0.0 0.0 0.0 8.0 0.0 0.4 6.6 0.6 0.4 2.3 4.5 0.0 0.4 0.8 0.1 0.1 1.0 0.1 SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 57.9;Exocrine glandular cells: 68.5;Inhibitory neurons: 57.2;Pancreatic endocrine cells: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.8" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.8;T-cells: 6.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cell Junctions" "HPA047008: AB_2679901" "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" 7.8 6.0 11.2 5.2 11.7 4.6 5.7 10.9 12.8 6.2 3.2 6.2 1.1 6.8 2.3 3.4 5.6 7.6 6.2 12.5 11.1 2.5 38.7 3.6 5.9 11.4 9.1 6.7 2.4 0.3 8.5 3.9 12.7 4.1 2.7 12.8 2.4 5.0 3.0 3.0 3.7 7.7 7.0 3.6 4.9 3.6 10.0 3.6 2.9 3.5 5.6 6.5 4.9 11.2 4.9 2.1 5.2 10.5 26.0 20.7 0.0 22.0 7.8 3.2 3.0 2.5 3.0 29.3 3.7 24.3 5.1 1.4 12.2 9.3 4.8 24.7 7.5 30.2 7.5 21.8 13.5 22.5 8.8 18.7 10.8 7.7 27.3 11.1 15.3 8.3 10.1 22.1 10.7 1.7 15.3 10.8 4.4 0.1 6.4 0.0 6.0 12.2 9.0 2.4 17.5 14.9 10.0 2.3 6.0 1.4 2.6 13.4 17.6 7.5 4.3 11.6 6.9 16.8 14.2 21.7 8.7 17.5 3.0 0.0 0.1 0.0 4.9 0.0 6.4 5.1 5.1 4.1 0.9 3.0 3.1 3.8 0.0 11.8 0.1 1.6 2.4 1.8 11.2 11.7 10.9 12.8 12.5 11.1 11.4 9.1 12.7 7.0 10.0 11.2 13.9 0.0 0.5 15.0 15.6 4.8 3.4 2.0 6.2 9.7 3.1 2.8 2.5 8.6 1.1 0.0 27.1 0.5 6.5 0.2 0.0 14.1 12.1 1.1 8.6 17.8 3.0 17.2 57.9 68.5 2.3 13.2 22.4 0.9 1.3 10.3 6.1 39.5 1.4 8.4 57.2 1.1 4.1 1.3 5.3 6.9 5.6 3.4 10.6 5.6 3.9 0.7 0.0 32.6 17.6 94.7 0.3 5.3 12.0 4.9 0.0 1.4 1.1 2.3 6.6 16.5 11.5 5.8 4.2 5.6 3.8 0.3 7.9 4.8 0.3 1.3 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SLITRK3 KIAA0848 ENSG00000121871 "SLIT and NTRK like family member 3" O94933 3 165186720-165197109 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0;fallopian tube: 9.6;liver: 7.9" "Group enriched" "Detected in some" 6 "Bipolar cells: 8.4;Excitatory neurons: 11.0;Inhibitory neurons: 15.9;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in single" 22 "glioma: 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.6;HAP1: 2.2;SCLC-21H: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017636, HPA048042" Enhanced Approved Mitochondria No NA 2600000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA017636: AB_1857232, HPA048042: AB_2732542" "unprognostic (8.91e-2)" "unprognostic (1.44e-1)" "unprognostic (4.08e-2)" "unprognostic (1.96e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-1)" "unprognostic (9.59e-2)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-1)" "unprognostic (6.74e-3)" "unprognostic (5.03e-1)" "unprognostic (2.38e-1)" "unprognostic (8.03e-4)" 0.1 0.1 3.4 1.0 3.1 0.0 0.1 4.1 8.4 5.4 0.0 2.6 0.4 7.3 0.9 4.4 9.6 0.2 0.4 9.0 2.8 0.1 7.9 0.3 0.0 0.2 0.1 0.9 0.0 0.0 0.1 0.0 0.5 1.7 1.6 3.1 0.2 5.4 0.3 0.0 1.1 3.7 0.9 0.0 0.4 0.4 0.7 0.0 0.1 0.0 0.0 0.5 0.9 1.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.1 4.1 8.4 9.0 2.8 0.2 0.1 0.5 0.9 0.7 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 2.2 0.0 0.0 15.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 21.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMIM13 C6orf228 ENSG00000224531 "Small integral membrane protein 13" P0DJ93 6 11093834-11138733 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 75.1;Syncytiotrophoblasts: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065706 Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Nuclear membrane, Golgi apparatus" "HPA065706: AB_2685539" "unprognostic (6.89e-2)" "unprognostic (1.22e-1)" "unprognostic (1.58e-1)" "unprognostic (7.11e-3)" "unprognostic (4.01e-1)" "unprognostic (2.57e-1)" "unprognostic (3.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (6.66e-2)" "unprognostic (1.30e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.04e-2)" "unprognostic (2.76e-1)" "unprognostic (9.22e-2)" "unprognostic (3.45e-2)" 4.7 4.6 15.4 3.4 16.1 2.9 3.4 21.4 23.8 4.3 5.6 4.1 3.6 5.0 3.4 4.8 2.9 4.1 6.6 16.7 18.0 4.3 9.7 3.5 3.0 17.6 16.7 4.1 3.0 6.4 4.1 12.7 19.3 4.6 3.6 17.1 3.7 4.8 11.5 4.9 3.1 5.2 15.8 2.9 3.1 3.4 20.0 3.4 3.0 14.2 3.0 4.9 3.7 19.4 9.9 8.3 12.6 10.6 12.7 14.4 13.2 26.7 11.3 13.4 14.9 11.1 3.1 12.1 35.9 8.6 13.3 8.6 26.3 9.3 24.0 7.1 19.1 12.7 9.1 8.8 16.9 23.8 2.9 17.4 25.5 13.7 18.0 10.6 14.4 11.0 18.3 5.0 25.7 5.4 10.1 14.0 5.9 6.5 7.1 13.5 23.1 17.2 8.2 7.6 29.4 16.3 5.6 18.2 32.4 17.2 4.6 9.9 20.7 20.3 15.0 8.6 18.1 9.5 33.0 17.1 4.8 9.9 31.8 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.0 15.4 16.1 21.4 23.8 16.7 18.0 17.6 16.7 19.3 15.8 20.0 19.4 14.3 12.8 1.5 12.4 9.1 75.1 17.1 13.7 10.8 16.4 10.6 10.3 12.7 12.8 5.2 11.0 20.9 29.3 14.4 5.7 3.9 5.2 10.3 11.8 15.6 11.4 3.6 11.8 26.8 7.4 36.6 11.9 6.1 12.0 10.8 4.2 7.9 25.6 13.5 30.3 31.4 8.1 10.2 8.1 29.4 4.3 2.8 12.0 16.0 10.3 6.3 7.6 7.2 18.6 28.0 10.5 3.1 4.1 14.6 18.8 5.8 7.8 4.6 15.2 0.0 7.7 9.8 16.8 24.8 12.7 39.5 65.1 12.9 10.4 8.7 16.2 SMO "FZD11, SMOH" ENSG00000128602 "Smoothened, frizzled class receptor" Q99835 7 129188633-129213545 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 27.4;Granulosa cells: 13.0;Leydig cells: 20.8;Muller glia cells: 16.6;Peritubular cells: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 45.3;AN3-CA: 84.9;NTERA-2: 64.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011446 Approved NA NA "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "CAB011446: " "unprognostic (2.48e-2)" "unprognostic (2.69e-2)" "unprognostic (7.09e-2)" "unprognostic (1.10e-1)" "unprognostic (8.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.38e-3)" "unprognostic (1.59e-1)" "unprognostic (1.17e-2)" "unprognostic (8.74e-3)" "unprognostic (1.62e-1)" "unprognostic (5.15e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-1)" "unprognostic (2.61e-2)" 5.2 6.0 9.4 2.6 10.8 0.4 5.5 9.9 9.6 27.4 18.4 9.6 2.5 19.2 18.6 12.0 14.5 8.4 8.0 8.9 10.0 19.0 23.9 3.6 2.2 12.4 12.4 28.3 6.3 16.1 19.2 2.6 9.9 20.0 2.1 2.0 11.5 12.3 3.7 17.1 5.7 8.1 11.8 2.8 6.3 5.6 11.4 4.4 9.1 3.7 2.0 9.0 16.7 9.7 1.6 18.2 45.3 84.9 1.1 0.2 14.3 5.2 6.7 10.1 5.8 13.8 0.1 0.0 13.9 10.4 22.8 28.3 27.4 1.5 3.9 0.0 23.0 9.4 0.0 22.5 5.5 0.4 0.0 16.2 11.0 3.3 0.0 19.9 5.8 24.9 1.5 0.0 3.1 0.0 24.4 0.1 64.2 0.0 5.3 35.1 19.7 0.0 5.2 0.0 1.3 30.2 0.0 0.0 12.3 16.8 11.1 5.8 0.0 0.7 14.1 17.6 10.1 0.6 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 10.8 9.9 9.6 8.9 10.0 12.4 12.4 9.9 11.8 11.4 9.7 0.4 0.0 0.0 27.4 0.2 1.9 2.3 3.9 2.8 0.7 3.3 5.2 1.4 2.8 3.8 11.0 0.0 0.3 0.4 0.0 1.9 3.4 0.4 1.0 8.6 0.6 0.0 0.0 1.4 1.1 0.3 7.6 0.0 1.3 0.0 13.0 1.4 8.4 4.2 0.0 0.8 0.1 2.0 1.6 1.8 1.3 20.8 1.0 0.0 3.7 0.6 16.6 0.0 4.5 0.5 1.3 0.1 21.8 0.0 2.7 0.0 3.9 0.7 0.4 6.6 3.5 3.9 0.0 2.0 3.3 2.8 0.5 0.1 6.9 0.6 0.7 SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;liver: 67.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.4;Oligodendrocyte precursor cells: 372.4;Oligodendrocytes: 81.1;Peritubular cells: 133.2" "Cancer enhanced" "Detected in many" "glioma: 27.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 50.3;HeLa: 122.6;HSkMC: 38.3;SiHa: 72.1;SK-BR-3: 30.6;U-266/70: 42.3;U-87 MG: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 140000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "CAB034427: AB_2193382, HPA004153: AB_1080035" "unprognostic (3.31e-1)" "unprognostic (2.17e-3)" "unprognostic (8.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.09e-3)" "unprognostic (4.76e-2)" "unprognostic (2.80e-2)" "unprognostic (5.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.09e-2)" "unprognostic (3.92e-1)" "unprognostic (2.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" 15.9 10.3 29.2 0.5 30.3 0.1 6.2 53.2 29.1 9.4 17.5 1.3 1.9 2.2 7.7 0.3 6.6 0.5 8.3 27.9 31.6 3.0 67.9 0.6 0.9 38.4 38.8 1.4 10.3 0.3 4.4 8.0 36.8 33.4 1.0 2.4 5.8 38.8 12.7 2.4 1.4 1.0 41.2 27.2 3.8 35.7 29.6 0.4 4.2 2.7 0.5 1.3 6.3 52.8 0.0 3.3 50.3 0.0 9.8 6.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 2.9 0.0 0.0 20.4 0.0 122.6 17.4 0.1 0.0 0.0 38.3 11.9 1.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.0 0.2 72.1 30.6 0.0 0.3 0.0 0.0 0.4 0.3 2.9 0.0 0.0 42.3 0.0 0.0 51.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.2 30.3 53.2 29.1 27.9 31.6 38.4 38.8 36.8 41.2 29.6 52.8 0.3 0.0 0.0 12.1 2.5 0.3 0.0 0.7 0.0 2.1 1.3 3.8 2.0 7.2 0.1 0.0 16.7 24.2 4.0 0.0 0.0 0.3 4.7 11.9 0.6 2.9 15.6 0.0 1.0 2.3 0.8 6.0 3.6 1.5 0.0 1.4 3.3 104.4 2.8 0.0 13.5 0.1 14.2 2.5 0.4 19.0 7.8 0.3 0.0 1.0 0.1 0.3 0.0 372.4 81.1 3.7 0.1 133.2 12.4 0.0 0.0 0.0 1.1 0.3 0.0 0.7 2.3 2.1 3.9 0.0 0.4 40.2 0.4 0.4 0.0 0.1 SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659666-31668931 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1645.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 3357.9;Proximal tubular cells: 3285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 44900000 50000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Plasma membrane, Cytosol" "CAB008670: AB_1623312, HPA001401: AB_1080132" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (4.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.39e-1)" "unprognostic (9.59e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (5.28e-2)" "unprognostic (9.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (3.26e-2)" 257.6 597.1 558.0 118.4 577.4 166.4 233.5 605.2 805.1 206.6 586.6 251.0 360.3 179.5 228.4 221.1 197.1 206.0 477.3 575.1 619.9 483.2 1645.6 153.9 169.6 619.8 604.6 302.1 117.1 210.6 236.7 155.8 653.1 203.9 180.5 248.6 160.5 204.2 428.0 152.1 266.7 136.6 588.1 147.5 210.4 132.1 585.8 165.7 197.4 355.9 151.7 232.1 220.6 634.7 526.8 451.4 309.2 312.8 407.3 282.1 257.8 430.2 258.0 291.3 217.4 593.6 326.0 628.2 441.2 405.8 517.7 186.1 453.3 320.6 239.9 463.3 540.0 1008.2 579.5 866.3 267.4 451.7 363.1 294.8 240.6 406.5 225.2 327.9 331.2 469.0 704.4 773.2 357.4 860.0 489.0 454.5 466.1 830.0 475.4 413.0 622.0 981.4 579.4 320.5 335.9 281.4 805.1 419.4 438.3 279.2 484.3 393.4 387.4 222.9 489.2 304.7 322.0 583.4 1374.2 741.8 455.7 654.3 301.9 204.2 159.7 194.0 313.4 234.0 365.3 427.1 509.2 402.4 212.8 310.1 521.8 412.1 37.8 241.4 465.4 240.6 746.0 474.5 558.0 577.4 605.2 805.1 575.1 619.9 619.8 604.6 653.1 588.1 585.8 634.7 319.8 294.9 175.1 38.2 248.1 491.4 672.7 479.2 319.8 226.6 264.1 352.9 721.0 527.6 294.7 391.8 47.9 703.4 250.2 703.5 1631.7 426.3 277.0 410.7 241.2 261.0 288.4 898.8 39.7 807.3 574.9 365.8 198.8 216.3 220.0 278.9 318.1 3357.9 363.3 282.7 45.5 402.7 366.2 220.0 318.5 952.2 521.9 224.2 419.8 29.0 313.1 598.5 239.0 28.6 68.7 322.8 600.9 528.1 178.2 567.0 1158.3 3285.9 638.3 216.5 440.4 313.6 404.5 211.7 506.3 379.9 349.8 725.9 423.1 470.3 593.6 497.7 SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 79.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 387.8;Excitatory neurons: 247.4;Microglial cells: 404.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 125.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 125.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 142.8;Daudi: 68.7;OE19: 93.5;RT4: 102.1;U-698: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" NA NA 79000 "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB011500: AB_443414, HPA031321: AB_2673826" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (9.53e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-3)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.80e-7)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-2)" 7.0 6.1 29.1 24.4 39.1 47.4 13.9 49.5 35.5 44.4 0.0 17.3 11.6 5.4 8.9 5.4 40.1 7.3 2.4 33.8 39.7 19.0 58.2 10.4 21.1 40.3 46.8 9.0 8.0 10.4 16.8 2.3 47.0 20.8 16.9 20.3 21.8 25.4 1.7 3.4 18.1 4.5 45.3 21.8 10.3 5.1 38.8 17.0 13.5 4.0 23.0 15.7 6.6 79.1 1.3 8.1 7.3 1.1 0.0 0.0 7.4 0.4 2.4 0.3 0.0 11.9 142.8 68.7 8.5 1.8 10.5 47.4 9.1 7.0 0.1 0.0 2.6 0.0 10.3 16.8 0.1 29.6 0.1 0.0 7.6 0.0 25.8 4.0 0.0 8.7 0.0 0.7 0.0 9.7 7.1 15.3 8.8 93.5 10.8 7.7 0.4 1.6 15.8 102.1 5.1 1.5 15.2 21.5 0.0 16.0 21.0 9.5 0.3 0.1 4.9 1.0 0.0 0.0 0.0 139.8 0.1 38.6 0.4 44.3 15.9 59.1 22.1 6.9 29.3 1.9 24.6 20.0 6.6 5.1 23.1 20.8 125.7 20.9 9.4 16.4 19.3 21.2 29.1 39.1 49.5 35.5 33.8 39.7 40.3 46.8 47.0 45.3 38.8 79.1 1.6 6.4 23.3 160.9 20.7 4.5 42.3 23.3 18.2 68.8 44.5 22.0 12.3 18.6 36.8 79.1 387.8 0.4 130.1 132.1 0.0 10.3 1.2 21.6 2.9 10.3 6.1 8.8 247.4 0.7 0.7 5.8 14.3 24.7 12.0 20.6 34.6 114.5 39.1 50.5 80.1 54.6 40.7 62.4 16.9 5.0 77.9 67.0 3.6 404.7 97.5 28.0 146.2 74.9 86.0 6.4 81.1 57.9 28.6 36.1 168.6 1.0 15.6 31.2 0.0 19.5 10.3 2.9 18.8 20.8 2.4 0.4 60.2 32.7 42.2 33.4 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 1.5 2.0 4.7 1.9 5.3 2.2 11.0 7.4 8.8 3.9 0.1 2.4 4.1 1.7 3.0 11.0 1.7 1.7 1.0 5.5 3.2 4.6 29.0 1.9 2.3 6.0 3.3 2.5 2.3 1.4 1.1 1.0 6.3 1.5 2.3 3.8 2.7 1.1 1.3 13.6 4.1 1.6 1.8 1.4 2.5 1.5 6.9 1.6 1.3 0.7 4.1 1.1 6.6 8.3 5.2 6.1 8.0 6.7 7.6 7.3 3.5 5.7 4.5 5.7 3.5 6.0 5.3 7.1 8.1 8.7 9.1 9.8 6.6 4.0 6.0 4.3 2.6 2.2 15.3 3.7 3.4 3.3 1.8 5.4 11.3 4.1 3.2 4.2 2.9 2.7 3.7 6.2 7.5 7.1 1.4 3.6 4.5 4.1 4.7 5.1 5.8 2.0 7.6 5.4 14.0 6.4 18.2 7.6 5.8 6.1 2.6 0.9 5.8 8.6 3.4 14.2 7.6 2.3 3.6 2.6 7.2 3.6 8.0 3.5 1.3 0.5 0.3 1.0 0.2 0.5 0.3 0.5 1.6 0.6 0.2 0.3 0.7 0.5 1.1 0.7 0.4 0.5 4.7 5.3 7.4 8.8 5.5 3.2 6.0 3.3 6.3 1.8 6.9 8.3 3.7 3.2 2.7 7.8 11.9 18.5 6.7 19.0 67.2 5.0 14.5 9.1 2.6 11.5 12.8 5.5 4.2 0.9 5.0 8.3 7.9 9.8 8.1 2.6 4.3 3.2 2.4 4.4 15.5 4.7 7.4 4.7 16.3 3.2 1.3 6.0 4.6 103.4 13.0 6.7 14.9 7.2 52.9 19.4 11.6 2.6 3.4 11.6 7.2 6.5 50.7 5.1 10.3 9.0 7.6 6.7 10.4 7.9 7.2 9.4 24.9 23.4 10.4 3.8 0.0 3.7 6.1 3.4 4.4 139.2 30.4 0.8 5.9 5.2 12.0 10.2 SS18L1 "CREST, KIAA0693" ENSG00000184402 "SS18L1 subunit of BAF chromatin remodeling complex" O75177 20 62143769-62182514 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011827, HPA059046" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "CAB011827: AB_778216, HPA059046: AB_2683888" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "unprognostic (1.54e-1)" "unprognostic (3.03e-2)" "unprognostic (6.57e-2)" "prognostic favorable (8.00e-5)" "unprognostic (1.39e-1)" "prognostic favorable (3.74e-4)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" "unprognostic (2.47e-3)" "unprognostic (6.43e-2)" "unprognostic (2.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (9.94e-3)" 7.7 8.8 11.3 6.6 10.1 6.6 7.8 26.1 13.9 10.3 7.5 8.2 7.7 8.0 8.4 10.9 9.2 5.0 8.3 9.7 9.7 10.5 37.8 9.7 6.4 12.2 9.5 10.6 12.1 6.4 11.9 7.1 11.6 9.0 6.1 10.7 8.5 5.4 13.3 19.8 8.4 5.6 6.7 10.1 9.2 8.9 11.1 6.5 9.1 9.4 5.8 8.5 10.1 18.9 11.1 12.5 17.7 16.3 7.6 8.8 12.9 10.3 3.9 16.6 8.0 44.1 10.2 6.6 13.3 5.8 8.6 27.9 10.5 9.8 15.2 4.5 6.9 29.6 30.9 23.5 5.7 11.2 25.6 5.5 20.5 8.4 7.0 9.7 7.5 11.3 20.3 12.8 9.6 13.2 16.7 17.2 7.3 11.0 13.7 18.5 23.1 7.8 12.5 13.9 33.4 18.6 17.7 22.4 15.6 11.3 20.8 17.6 9.3 31.8 19.0 12.0 14.6 13.8 13.2 5.6 15.9 10.6 10.9 0.0 0.4 0.1 0.3 0.3 0.2 0.1 0.2 0.3 0.3 1.2 0.6 0.2 0.6 0.4 0.7 0.2 0.2 0.1 11.3 10.1 26.1 13.9 9.7 9.7 12.2 9.5 11.6 6.7 11.1 18.9 9.7 9.6 7.0 19.6 5.2 16.4 4.8 8.9 17.1 17.9 10.8 8.8 10.3 2.8 11.4 7.3 22.9 5.6 6.7 7.1 3.9 5.0 10.8 11.9 8.1 9.7 14.3 4.8 29.5 2.7 3.3 8.9 7.7 12.8 1.3 10.8 8.6 40.4 4.8 15.2 32.8 6.6 14.2 10.4 12.7 20.8 7.5 7.4 12.4 20.6 10.0 4.4 4.1 8.5 25.5 8.2 7.3 3.4 7.4 9.5 8.3 9.1 9.0 16.5 6.6 11.1 7.7 4.6 10.2 10.6 17.5 7.7 6.0 10.6 7.1 6.9 ST3GAL6 "SIAT10, ST3GALVI" ENSG00000064225 "ST3 beta-galactoside alpha-2,3-sialyltransferase 6" Q9Y274 3 98732236-98821201 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 128.8;Hepatocytes: 86.8;Microglial cells: 134.0;Oligodendrocyte precursor cells: 171.4" "Cancer enriched" "Detected in many" 5 "melanoma: 17.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.6;neutrophil: 57.6" "Group enriched" "Detected in many" 143 "dendritic cells: 24.2;granulocytes: 57.6;monocytes: 17.4" "Group enriched" "Detected in many" 4 "RPMI-8226: 96.5;SK-MEL-30: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018792 Approved NA NA 5800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA018792: AB_10964349" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (4.17e-2)" "unprognostic (5.20e-3)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (2.30e-3)" "unprognostic (2.40e-1)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "unprognostic (4.32e-1)" "unprognostic (3.91e-3)" "unprognostic (6.15e-3)" "unprognostic (9.44e-2)" "unprognostic (9.47e-3)" "unprognostic (6.79e-4)" 14.6 7.9 8.2 3.8 8.9 2.4 6.3 14.0 9.9 4.8 3.0 3.8 2.0 2.2 12.0 1.9 6.3 2.2 26.5 9.3 8.5 14.0 56.0 7.8 1.6 19.5 10.1 1.2 3.5 1.1 4.1 8.5 14.3 3.3 2.7 1.5 19.5 2.0 7.9 16.7 1.9 2.0 14.8 3.2 4.5 1.6 9.2 10.6 2.9 6.4 2.8 1.6 1.4 13.1 0.3 1.3 1.8 2.7 3.3 1.1 12.5 0.4 1.5 1.2 2.2 8.7 0.5 6.4 3.3 0.0 4.6 2.1 3.9 2.0 1.1 0.0 2.7 0.2 0.6 15.1 14.0 13.2 23.7 1.5 0.1 3.5 6.6 22.4 14.2 2.6 0.0 6.3 1.3 0.0 2.1 22.6 3.5 0.0 3.5 1.3 1.5 96.5 3.4 0.0 3.8 19.2 5.1 0.5 114.2 3.6 0.4 23.1 10.8 2.9 2.4 0.8 1.3 24.1 2.0 0.0 4.6 18.6 10.3 18.5 17.4 49.6 0.0 9.6 0.0 0.1 0.0 0.0 24.2 0.0 0.2 0.0 57.6 0.1 4.9 5.5 0.0 4.7 8.2 8.9 14.0 9.9 9.3 8.5 19.5 10.1 14.3 14.8 9.2 13.1 10.1 12.8 35.2 2.3 2.3 11.5 2.6 7.0 2.2 1.2 6.4 5.7 40.4 2.8 2.8 3.7 8.4 45.2 0.0 0.0 13.7 6.8 0.3 128.8 4.2 20.2 16.1 6.6 78.5 2.0 69.5 3.8 9.2 41.0 39.1 1.8 32.5 86.8 34.4 0.0 64.2 0.1 30.5 29.5 64.2 1.0 2.8 38.4 65.8 134.0 38.0 0.9 0.0 171.4 51.6 6.2 0.1 6.8 18.0 5.2 0.0 10.0 27.5 3.5 6.6 1.7 2.2 0.1 1.0 2.1 12.8 27.0 2.0 0.3 0.3 1.8 SUMO4 "dJ281H8.4, IDDM5, SMT3H4" ENSG00000177688 "Small ubiquitin like modifier 4" Q6EEV6 6 149400262-149401278 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.1;Glandular and luminal cells: 8.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "HeLa: 1.0" "HPA042123, HPA048064" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Nuclear bodies" "HPA042123: AB_2677860, HPA048064: AB_2680244" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (2.16e-2)" "unprognostic (3.24e-3)" "unprognostic (8.61e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-1)" "unprognostic (7.75e-2)" "unprognostic (4.32e-2)" "unprognostic (1.35e-1)" "unprognostic (4.72e-2)" "unprognostic (5.36e-2)" "unprognostic (2.44e-11)" "unprognostic (4.94e-3)" "unprognostic (5.88e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-2)" 0.5 0.3 1.0 0.3 0.7 0.7 0.3 1.7 1.2 1.1 1.2 0.4 0.2 0.2 0.1 0.6 0.5 0.2 0.8 0.5 0.7 0.8 1.3 1.0 0.5 1.9 0.9 0.9 0.4 0.0 0.8 0.3 1.2 1.0 0.2 0.7 0.4 0.1 0.2 0.4 0.3 0.1 1.0 0.6 0.3 0.6 1.5 0.1 0.6 0.0 0.2 0.6 1.1 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.3 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.4 0.5 0.2 0.2 0.4 1.0 0.7 0.2 0.6 0.6 0.9 2.2 1.0 0.5 0.2 1.1 0.2 1.0 0.7 1.7 1.2 0.5 0.7 1.9 0.9 1.2 1.0 1.5 1.6 2.0 3.2 1.5 0.0 3.1 2.9 1.8 0.9 0.0 4.3 2.5 1.8 11.1 1.5 0.9 1.8 4.2 0.7 6.4 1.3 0.0 0.7 0.1 4.5 4.0 2.7 1.8 0.8 0.0 0.9 0.4 2.9 2.0 8.4 1.3 7.2 1.4 1.6 1.1 0.0 0.0 0.5 0.0 1.3 4.7 0.9 2.1 5.1 0.0 0.0 3.9 1.7 1.0 0.0 0.0 1.1 1.2 1.2 3.5 3.5 1.0 0.4 1.0 3.9 6.6 1.8 3.6 1.9 0.8 0.5 0.9 0.3 4.3 2.7 0.4 3.9 TBC1D9B "GRAMD9B, KIAA0676" ENSG00000197226 "TBC1 domain family member 9B" Q66K14 5 179862066-179907897 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038350 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Nucleoli fibrillar center" "HPA038350: AB_10673170" "unprognostic (5.06e-2)" "unprognostic (1.37e-1)" "unprognostic (1.60e-2)" "unprognostic (9.53e-2)" "unprognostic (9.45e-3)" "unprognostic (4.25e-1)" "unprognostic (1.06e-1)" "unprognostic (2.84e-1)" "unprognostic (1.10e-1)" "unprognostic (5.08e-2)" "unprognostic (2.01e-1)" "unprognostic (2.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (8.22e-2)" 54.9 61.8 53.9 20.8 62.2 22.8 46.3 58.1 51.1 39.3 38.6 34.1 22.8 38.9 12.0 43.9 34.2 23.8 30.9 51.4 50.1 44.8 55.0 31.7 23.9 60.5 59.8 39.0 46.4 27.0 29.2 17.2 61.6 33.6 12.1 9.1 37.0 25.0 45.9 44.4 34.4 21.1 63.4 39.5 35.5 20.5 57.2 13.1 36.3 18.7 15.3 35.1 35.7 65.9 42.7 64.0 27.4 62.4 69.9 49.0 66.8 51.0 47.2 50.1 48.4 43.8 41.9 29.3 60.2 57.8 56.6 39.6 28.3 115.9 9.8 98.0 39.1 26.0 47.3 27.9 41.5 35.1 85.0 50.6 42.6 39.2 18.9 22.6 48.4 55.3 17.7 28.1 39.5 104.2 22.7 24.5 20.3 17.4 36.5 38.7 22.1 27.8 35.1 66.8 40.1 30.4 48.2 54.5 54.9 11.0 45.0 48.8 57.2 71.2 31.9 34.8 45.2 16.8 23.3 22.7 68.0 41.7 51.7 5.0 7.8 5.5 6.1 9.2 4.8 6.3 4.2 4.9 9.3 5.1 3.9 3.5 0.9 4.2 9.2 9.5 4.0 7.1 53.9 62.2 58.1 51.1 51.4 50.1 60.5 59.8 61.6 63.4 57.2 65.9 24.9 22.4 19.2 20.2 19.7 16.6 10.2 14.6 15.4 27.8 23.9 21.6 9.5 12.8 14.0 27.6 8.4 19.8 20.4 28.4 13.7 21.1 2.4 18.2 20.2 21.0 18.0 17.5 32.1 18.0 23.6 21.1 21.9 27.0 11.4 30.0 24.3 35.2 30.7 62.2 23.6 23.9 10.2 33.5 15.7 8.2 32.3 28.6 16.0 15.9 21.4 17.8 24.7 14.6 27.0 25.2 24.3 28.6 16.4 15.3 24.4 22.6 13.3 18.0 26.3 26.7 16.4 11.1 18.5 25.0 15.6 14.1 17.9 57.1 20.5 13.7 TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "liver: 7525.8;retina: 2433.0" "Group enriched" "Detected in many" 9 "Hepatocytes: 7205.2;Muller glia cells: 12965.3" "Cancer enriched" "Detected in many" 42 "liver cancer: 783.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 48 "Hep G2: 780.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" NA NA 19800000000000 98000000000 "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "CAB009538: AB_793365, HPA001527: AB_1080357, HPA005692: AB_1080354" "prognostic favorable (4.05e-4)" "unprognostic (2.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.50e-1)" "unprognostic (8.99e-2)" "unprognostic (5.18e-2)" "unprognostic (6.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (2.35e-13)" "unprognostic (2.17e-3)" "unprognostic (5.49e-2)" "unprognostic (3.47e-3)" "unprognostic (9.70e-2)" 80.9 1.2 186.3 1.0 412.5 2.4 13.3 591.8 274.2 2.0 58.9 2.3 0.9 1.7 1.4 11.0 1.4 1.9 12.1 173.7 287.7 3.4 7525.8 1.9 1.3 786.9 385.4 2.1 4.6 2.2 4.4 1.3 628.2 5.4 1.2 2433.0 55.8 1.8 2.1 4.2 1.6 1.5 484.9 2.9 1.9 14.3 398.1 1.2 2.2 2.7 3.0 1.2 2.8 862.1 1.9 1.4 1.8 1.2 5.5 3.4 0.9 1.9 2.0 1.0 0.8 3.4 1.5 1.7 1.6 1.8 1.2 2.1 1.3 1.8 1.5 1.1 0.7 16.3 2.7 780.9 1.3 4.6 2.7 2.4 3.8 1.0 1.7 1.8 2.2 0.9 6.4 2.1 2.6 1.3 1.1 1.2 1.2 1.2 1.8 1.5 2.9 1.2 1.1 3.1 1.9 1.4 2.4 2.6 7.0 1.3 1.9 1.3 2.9 2.4 1.5 1.6 1.1 1.7 3.0 1.4 2.0 1.5 1.6 0.6 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 186.3 412.5 591.8 274.2 173.7 287.7 786.9 385.4 628.2 484.9 398.1 862.1 0.7 16.0 32.4 36.2 11.4 1.0 5.6 0.6 0.0 101.3 5.3 4.3 2.7 117.2 22.9 0.0 91.8 0.2 0.2 0.1 1.9 0.7 5.4 0.8 1.0 16.7 0.0 56.2 34.2 1.1 0.3 3.9 0.0 0.6 17.7 1.3 87.4 7205.2 0.1 47.1 34.7 0.0 0.0 124.7 0.3 3.8 0.3 4.7 0.0 9.4 0.6 12965.3 0.0 45.2 1077.2 1.1 0.0 0.4 0.0 18.7 0.0 0.5 22.1 400.4 0.0 11.6 0.4 0.5 0.4 3.6 0.0 0.3 7.8 0.5 0.0 3.0 THNSL1 "FLJ22002, TSH1" ENSG00000185875 "Threonine synthase like 1" Q8IYQ7 10 25016612-25026664 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 21.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.6;Early spermatids: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037585 Uncertain Approved "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies, Cytosol" Mitochondria "HPA037585: AB_10696940" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (4.31e-2)" "unprognostic (5.26e-2)" "unprognostic (6.11e-2)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (9.75e-2)" "unprognostic (2.63e-2)" "unprognostic (1.52e-1)" "unprognostic (1.71e-3)" "unprognostic (2.08e-1)" "unprognostic (3.21e-2)" "unprognostic (9.84e-3)" "unprognostic (3.06e-2)" 1.7 6.0 4.0 1.8 4.2 0.6 3.6 3.2 4.5 4.1 2.9 2.7 2.6 3.6 4.9 1.9 5.6 2.0 3.7 4.1 4.2 9.7 21.4 1.5 2.8 3.9 3.5 7.3 3.0 5.3 3.7 1.7 4.2 2.9 3.0 4.1 3.4 2.6 4.6 2.2 2.4 2.2 3.9 2.2 2.7 5.9 4.1 3.3 8.3 5.9 2.7 1.8 1.5 4.3 7.1 8.1 5.0 10.0 5.0 6.2 1.3 3.4 1.3 3.7 2.4 5.3 8.8 32.7 10.6 1.6 4.0 3.8 7.2 6.4 3.8 4.5 3.9 12.0 2.2 3.4 5.6 0.0 2.0 3.9 11.6 2.7 5.7 6.4 2.5 13.3 10.4 3.8 8.0 11.1 6.6 2.3 9.2 12.3 3.9 3.5 1.3 14.2 10.6 1.6 8.3 4.7 6.8 6.0 12.3 2.6 6.0 0.6 2.5 4.4 3.9 5.9 3.2 2.7 3.8 0.0 7.3 6.6 3.5 0.1 0.4 0.0 2.9 0.5 5.1 5.0 4.1 3.8 2.2 3.8 9.5 6.3 0.6 10.8 0.7 3.7 2.0 3.1 4.0 4.2 3.2 4.5 4.1 4.2 3.9 3.5 4.2 3.9 4.1 4.3 1.3 3.2 3.2 2.6 3.4 0.6 3.1 5.6 2.8 4.2 2.1 2.9 8.5 1.5 6.1 3.7 0.0 6.1 0.8 0.6 15.6 3.3 29.9 5.1 3.9 1.8 1.2 2.5 4.0 1.3 3.9 2.7 1.5 2.5 0.0 7.8 2.2 9.8 2.1 3.3 5.1 1.8 2.0 0.9 0.8 5.5 2.1 0.6 0.0 4.7 1.5 6.8 0.0 2.0 5.4 1.1 1.0 1.5 0.9 1.8 2.3 11.0 8.7 4.5 0.0 4.3 1.9 8.2 13.6 2.6 1.0 1.0 2.8 11.8 3.5 1.1 THPO "MGDF, MPLLG, TPO" ENSG00000090534 Thrombopoietin P40225 3 184371935-184381968 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 35.4" "Cell type enhanced" "Detected in some" "Early spermatids: 2.3;Hepatocytes: 12.7;Late spermatids: 4.0;Proximal tubular cells: 9.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.0;Hep G2: 15.6;K-562: 2.8;RPMI-8226: 4.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1070000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (5.57e-2)" "unprognostic (3.15e-2)" "unprognostic (1.75e-1)" "unprognostic (2.21e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (1.40e-3)" "unprognostic (4.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.25e-2)" 1.8 2.5 5.2 0.5 3.9 0.0 1.4 4.7 4.8 3.9 2.4 0.7 0.2 3.8 1.3 0.4 2.0 0.4 1.2 4.5 2.8 4.5 35.4 0.8 0.2 3.3 2.9 2.8 1.7 0.1 0.7 0.5 3.0 1.3 0.3 0.0 0.5 0.5 1.9 0.6 0.7 1.5 3.0 1.3 0.9 3.9 2.8 0.0 0.8 0.9 0.1 0.9 1.9 3.6 0.0 0.0 0.0 0.0 0.5 0.0 2.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 15.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.3 0.6 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 3.9 4.7 4.8 4.5 2.8 3.3 2.9 3.0 3.0 2.8 3.6 0.1 0.0 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 1.6 0.1 0.0 0.0 2.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 12.7 0.6 0.0 1.3 0.0 0.0 0.8 0.0 4.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 1.1 0.8 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 TMEM14A "C6orf73, PTD011" ENSG00000096092 "Transmembrane protein 14A" Q9Y6G1 6 52671113-52686588 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A-431: 253.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072536 Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Endoplasmic reticulum" "HPA072536: AB_2686531" "unprognostic (6.75e-2)" "unprognostic (3.65e-2)" "unprognostic (2.04e-1)" "unprognostic (8.10e-3)" "unprognostic (3.55e-2)" "unprognostic (1.06e-1)" "unprognostic (8.05e-2)" "unprognostic (4.10e-2)" "unprognostic (1.45e-1)" "unprognostic (2.56e-3)" "unprognostic (8.88e-2)" "unprognostic (1.17e-1)" "unprognostic (3.52e-2)" "unprognostic (9.60e-2)" "unprognostic (5.44e-2)" "unprognostic (3.37e-1)" "unprognostic (2.64e-1)" 20.7 46.8 51.9 13.6 52.7 10.3 24.9 52.7 78.4 25.8 72.6 25.3 38.3 27.7 36.4 36.2 31.3 25.0 16.5 53.3 62.6 51.5 106.4 18.0 19.7 55.1 50.5 39.8 36.2 22.2 24.2 16.1 55.8 36.4 25.9 31.4 21.7 21.6 4.4 13.9 35.4 26.4 52.5 13.7 40.8 17.2 55.0 15.5 28.6 8.5 23.9 24.4 26.2 55.4 253.4 37.5 27.3 77.6 73.1 56.0 23.1 50.0 68.0 45.2 69.5 57.8 63.5 30.8 54.2 63.1 94.9 93.9 61.3 83.7 75.3 125.0 50.1 45.6 57.4 95.7 24.0 23.6 54.7 50.5 57.8 49.5 11.1 59.5 61.7 38.9 9.8 85.4 54.1 51.3 46.4 26.9 16.2 165.9 64.7 36.0 38.8 24.5 88.5 48.1 141.4 68.5 55.6 44.2 97.1 33.9 68.0 44.8 45.8 62.0 83.3 24.5 81.3 40.9 37.1 46.6 87.4 14.8 50.7 23.3 0.5 16.4 38.4 0.1 24.8 54.6 48.7 40.4 19.4 36.0 36.9 39.4 2.1 11.0 0.1 35.2 66.5 30.3 51.9 52.7 52.7 78.4 53.3 62.6 55.1 50.5 55.8 52.5 55.0 55.4 28.6 25.6 17.6 13.1 23.4 48.4 61.9 183.5 56.9 20.4 71.3 72.4 17.4 54.3 90.1 51.5 8.4 56.1 27.5 22.6 64.6 108.1 1.4 31.2 33.3 37.3 33.5 32.8 50.3 140.9 150.8 62.4 50.0 26.3 25.4 46.5 38.6 138.7 47.0 5.0 45.7 53.1 77.3 7.0 56.6 2.5 43.5 10.9 88.9 16.9 4.9 27.1 16.5 15.1 15.5 74.7 25.2 50.0 18.6 48.5 77.4 152.7 85.5 13.2 6.6 38.6 60.7 4.3 41.2 139.5 38.2 15.5 30.9 22.0 51.7 69.3 TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 502.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA009078: AB_1078345, HPA061421: AB_2684513" "unprognostic (1.39e-1)" "unprognostic (3.61e-1)" "unprognostic (3.73e-1)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (9.67e-3)" "unprognostic (5.85e-3)" "unprognostic (4.34e-3)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-2)" "unprognostic (9.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.55e-2)" 140.5 120.1 89.7 60.4 98.6 60.4 88.4 101.9 110.7 108.3 113.6 83.9 62.3 88.9 120.4 57.3 87.1 97.7 101.4 88.2 100.2 145.7 197.8 75.8 81.0 98.9 95.1 97.4 95.1 99.3 89.5 72.5 99.1 105.5 88.7 107.4 78.9 83.1 107.1 34.4 70.2 88.9 95.3 71.8 87.6 49.7 96.0 85.6 135.5 148.3 76.6 93.3 56.6 111.8 157.2 108.1 139.1 105.2 307.1 271.6 105.6 124.0 185.4 119.9 131.4 86.0 152.4 74.8 99.5 180.7 136.6 127.1 104.5 185.2 172.3 83.6 119.6 132.6 31.5 266.3 196.3 154.9 52.8 189.3 202.4 92.2 183.3 167.0 160.1 163.6 126.1 200.3 199.2 44.7 156.9 143.8 106.3 298.8 152.4 100.4 93.2 161.5 182.5 79.4 116.8 141.7 74.6 154.8 270.0 149.0 123.9 145.6 135.7 154.7 90.5 150.1 135.2 133.2 284.3 147.5 62.5 132.2 166.3 128.9 175.4 116.7 136.5 187.1 166.3 170.7 145.8 145.3 163.8 153.1 150.8 148.6 55.7 153.9 180.6 161.2 147.6 349.2 89.7 98.6 101.9 110.7 88.2 100.2 98.9 95.1 99.1 95.3 96.0 111.8 126.6 57.7 64.6 15.3 123.4 70.4 126.7 148.7 65.4 89.6 151.7 133.7 51.3 111.5 95.1 154.5 64.6 173.4 127.8 55.0 502.9 146.6 200.3 77.1 103.2 109.5 95.8 103.7 20.2 111.2 208.8 141.6 59.1 64.1 114.1 82.8 126.7 147.5 212.8 62.2 27.7 123.1 126.1 162.9 172.9 89.5 212.2 121.9 199.3 14.0 215.6 113.9 151.4 13.0 49.6 100.2 130.0 220.4 161.7 129.6 102.0 363.2 81.9 113.3 85.5 100.4 128.0 99.4 97.5 68.1 60.5 148.0 118.2 184.2 125.6 152.1 TOLLIP IL-1RAcPIP ENSG00000078902 "Toll interacting protein" Q9H0E2 11 1274371-1309654 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 498.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038621, HPA038622" Enhanced Approved Cytosol NA NA 140000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA038621: AB_10673177, HPA038622: AB_10675946" "unprognostic (8.39e-2)" "unprognostic (1.89e-1)" "unprognostic (2.18e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (8.89e-2)" "unprognostic (2.51e-1)" "unprognostic (8.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.72e-1)" "unprognostic (1.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-2)" 26.8 35.4 58.2 12.4 73.5 13.6 25.8 27.5 80.9 35.9 17.6 26.3 25.5 23.5 11.5 93.4 22.4 18.4 31.3 85.0 39.4 43.1 113.3 26.6 14.2 39.9 39.1 24.6 58.2 18.9 54.2 12.1 39.8 31.4 8.2 11.4 31.6 20.5 76.2 75.9 23.4 11.1 32.9 28.8 31.9 73.4 42.7 13.2 24.7 22.7 14.2 33.5 48.8 56.5 31.4 32.6 16.3 18.6 34.0 21.2 14.2 27.2 24.5 31.3 27.7 35.4 19.5 14.6 25.6 25.3 47.9 27.7 14.7 33.4 8.5 30.1 30.1 11.9 6.9 54.2 48.4 22.8 29.0 32.1 38.5 18.6 17.9 17.1 19.7 21.7 19.9 38.5 26.1 26.3 29.1 27.9 20.0 33.9 42.1 21.8 16.6 14.6 20.9 41.3 43.5 25.5 24.4 29.4 30.7 8.3 23.3 25.7 36.0 33.8 14.4 14.4 16.0 38.8 37.8 18.3 53.2 14.9 27.0 45.4 126.6 139.6 33.4 114.0 27.8 38.8 35.3 31.5 99.9 50.0 27.4 26.1 179.1 44.5 108.8 52.4 48.8 77.3 58.2 73.5 27.5 80.9 85.0 39.4 39.9 39.1 39.8 32.9 42.7 56.5 19.5 9.6 19.3 15.0 27.8 66.9 43.9 71.7 23.3 42.6 30.3 24.6 22.8 58.6 30.9 23.9 8.4 49.2 28.0 50.8 70.5 66.3 173.6 11.7 14.8 24.9 51.6 45.0 35.1 69.2 41.1 27.6 19.4 15.8 38.1 20.7 37.9 112.2 92.1 74.0 17.0 30.8 48.8 38.4 33.1 498.2 21.8 48.3 71.2 16.9 50.6 38.1 19.6 10.6 15.0 76.3 53.7 30.9 33.4 55.7 66.6 110.1 15.4 20.6 6.6 18.5 24.5 100.7 39.6 76.3 98.9 104.4 22.0 27.4 29.3 74.0 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.5;Excitatory neurons: 101.9;Inhibitory neurons: 107.1;Spermatocytes: 97.1" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" 16.9 15.8 22.1 10.8 20.5 6.0 13.4 18.4 21.6 35.4 12.3 11.1 3.2 21.8 14.3 10.8 11.2 38.1 8.5 19.4 36.7 23.1 46.0 11.5 5.9 37.2 25.0 13.5 7.8 11.0 19.5 26.4 24.7 15.1 8.0 5.2 6.8 16.4 2.7 8.2 8.7 16.2 22.9 12.0 10.9 23.0 33.8 2.1 11.3 5.6 5.3 36.8 22.1 22.5 12.1 6.5 16.5 22.4 52.7 42.0 5.7 22.3 49.8 25.7 37.1 21.9 6.6 1.4 17.7 45.1 38.9 8.9 16.2 24.8 33.3 3.5 9.3 2.3 15.1 16.5 62.3 1.8 1.9 59.5 19.0 50.2 22.1 27.8 32.7 2.9 1.0 10.2 40.2 6.2 0.1 3.1 15.5 0.4 9.6 7.8 14.6 11.4 27.3 11.5 10.4 44.5 27.8 2.1 62.2 32.4 8.6 4.7 62.3 33.1 21.3 24.2 40.6 9.2 13.3 4.7 29.6 6.8 48.2 52.2 2.3 23.9 0.8 0.1 0.8 6.1 0.5 0.6 0.3 14.0 2.2 4.1 35.2 8.8 0.0 0.0 0.0 1.9 22.1 20.5 18.4 21.6 19.4 36.7 37.2 25.0 24.7 22.9 33.8 22.5 33.8 0.0 8.9 38.8 11.5 10.8 7.7 24.4 33.6 8.5 4.0 13.3 1.6 5.7 9.6 31.3 2.1 1.8 3.8 0.2 9.8 23.0 11.2 13.3 76.5 17.9 7.7 1.3 101.9 47.6 4.3 58.5 12.2 9.7 4.5 12.2 10.0 34.1 16.2 6.7 107.1 0.8 8.2 8.9 8.9 11.6 48.1 6.2 14.2 32.8 15.8 5.0 1.0 61.3 38.8 23.7 0.1 37.2 7.1 5.3 0.0 3.2 19.5 3.6 6.6 16.4 21.6 97.1 41.3 15.1 7.5 3.8 2.8 12.6 0.7 7.7 TRPV1 VR1 ENSG00000196689 "Transient receptor potential cation channel subfamily V member 1" Q8NER1 17 3565444-3609411 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 24.6" "Cell type enhanced" "Detected in many" "Astrocytes: 20.2;Cone photoreceptor cells: 16.7;Oligodendrocytes: 18.8;Rod photoreceptor cells: 26.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (3.96e-2)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "unprognostic (6.83e-2)" "unprognostic (3.21e-4)" "unprognostic (9.90e-2)" "unprognostic (2.95e-1)" "unprognostic (2.03e-1)" "unprognostic (2.56e-2)" "unprognostic (3.43e-3)" "unprognostic (6.17e-3)" "unprognostic (6.97e-4)" "unprognostic (4.25e-1)" "unprognostic (4.78e-1)" "unprognostic (3.81e-2)" "unprognostic (5.12e-3)" 5.9 4.9 6.6 1.6 7.8 1.0 6.0 7.6 8.4 9.9 5.1 5.7 7.3 4.7 2.2 3.3 6.8 1.8 7.6 6.6 6.5 8.1 24.6 3.2 2.4 7.2 8.0 10.2 7.8 1.2 5.8 2.0 7.2 6.0 2.4 12.9 4.3 1.6 6.6 5.5 8.6 1.6 6.3 4.3 5.9 5.0 7.3 2.0 4.7 1.7 1.7 5.0 6.9 10.5 2.3 4.1 3.1 3.7 3.5 3.4 2.9 1.1 1.8 2.0 1.8 0.8 1.1 0.9 1.6 1.4 1.3 9.8 2.0 0.5 1.3 5.6 4.7 0.5 2.1 4.3 1.6 0.3 3.8 4.2 2.0 2.7 1.2 1.8 0.4 2.1 0.3 1.6 1.2 2.2 1.6 0.7 2.3 0.4 2.1 4.6 2.1 0.7 1.6 1.6 1.4 3.0 1.7 3.2 1.7 2.3 6.0 1.6 1.3 0.7 1.8 2.8 1.6 1.3 0.8 0.3 1.2 1.6 1.5 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.2 0.0 0.0 6.6 7.8 7.6 8.4 6.6 6.5 7.2 8.0 7.2 6.3 7.3 10.5 1.8 0.0 2.6 20.2 0.7 0.0 0.5 0.0 2.8 9.5 3.2 2.3 0.3 4.3 1.3 5.5 16.7 1.2 0.6 2.3 0.0 0.5 2.5 3.3 1.7 1.3 1.2 0.4 10.5 0.7 0.3 1.7 11.2 2.9 0.0 5.4 2.5 7.9 0.8 6.7 10.3 1.9 0.0 0.6 0.0 0.5 4.7 1.4 0.0 4.7 0.9 2.3 4.1 8.5 18.8 0.5 0.5 3.8 0.5 0.6 6.6 2.2 2.2 26.0 0.0 5.9 1.9 0.8 1.2 1.8 0.0 0.8 0.6 9.5 2.1 0.4 TUBE1 "dJ142L7.2, FLJ22589, TUBE" ENSG00000074935 "Tubulin epsilon 1" Q9UJT0 6 112070663-112087529 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 199.6;Spermatocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-2197: 48.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA032073, HPA032074" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA032073: AB_10601773, HPA032074: AB_10601216" "unprognostic (4.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-2)" "unprognostic (7.36e-2)" "unprognostic (1.22e-1)" "unprognostic (8.36e-3)" "unprognostic (2.18e-1)" "unprognostic (1.04e-1)" "unprognostic (4.99e-3)" "unprognostic (1.70e-1)" "unprognostic (5.15e-3)" "unprognostic (1.64e-1)" "unprognostic (7.68e-2)" "unprognostic (2.50e-1)" "unprognostic (1.59e-3)" 12.3 9.0 9.8 5.0 10.1 4.1 11.0 11.7 16.8 15.6 9.9 11.8 5.0 17.0 8.3 6.8 16.4 8.8 17.5 9.7 10.0 12.3 40.1 7.9 7.3 10.4 10.2 15.2 10.9 7.5 14.4 9.1 10.4 11.0 6.2 10.1 6.7 8.4 5.8 11.3 7.6 10.3 10.2 6.9 11.7 27.1 10.1 4.8 10.6 4.8 5.4 12.6 10.4 11.4 2.1 2.8 7.6 24.0 17.5 9.2 6.3 8.6 13.7 5.9 11.6 4.2 4.2 8.0 5.4 3.6 9.2 6.4 8.7 3.8 12.2 4.1 7.8 2.8 2.0 6.1 25.0 15.4 10.1 10.0 25.1 8.1 20.9 8.5 7.4 22.8 15.6 10.8 4.8 1.7 8.8 20.5 7.6 12.1 5.2 10.3 4.7 5.2 9.0 2.0 11.5 10.1 7.0 6.0 26.4 6.6 4.8 36.5 4.3 5.3 4.9 48.2 9.2 3.2 1.1 8.7 7.7 18.2 13.8 0.0 0.4 1.1 1.1 0.5 3.3 1.5 2.4 1.5 0.8 1.1 3.2 2.7 0.3 1.8 0.8 0.6 2.5 0.9 9.8 10.1 11.7 16.8 9.7 10.0 10.4 10.2 10.4 10.2 10.1 11.4 27.6 6.4 16.7 25.8 13.4 24.6 17.8 12.3 15.4 23.0 15.0 13.3 17.5 11.5 13.5 22.0 35.5 4.1 9.8 6.8 15.6 12.5 199.6 12.1 12.0 16.7 6.1 19.1 58.2 18.0 12.3 18.8 7.7 7.7 16.5 11.5 18.5 71.9 7.2 13.5 68.3 11.4 4.1 6.7 10.2 49.8 15.5 6.2 7.2 21.5 4.6 11.8 9.2 31.7 82.0 12.6 9.0 19.9 10.9 13.2 12.7 25.6 14.6 28.0 19.7 13.3 13.4 97.0 27.0 12.7 12.5 3.3 14.8 35.0 8.0 14.8 VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.1;Endothelial cells: 142.7;Syncytiotrophoblasts: 290.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 47.2;CACO-2: 46.7;CAPAN-2: 136.6;Hep G2: 84.4;SCLC-21H: 47.6;T-47d: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 250000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (2.78e-1)" "unprognostic (4.85e-2)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (9.52e-3)" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" "unprognostic (3.08e-2)" "unprognostic (6.71e-2)" 36.2 15.2 55.3 31.5 91.7 0.2 38.4 79.4 76.7 51.0 24.4 114.3 15.3 70.4 11.5 41.3 50.4 22.4 38.0 59.4 58.9 58.6 133.3 29.6 13.7 103.4 81.6 22.5 55.3 12.5 20.0 38.4 87.9 131.3 5.3 2.3 64.0 203.6 10.1 26.2 37.6 20.4 74.2 11.7 52.6 27.1 88.3 3.0 67.4 3.4 5.1 118.5 50.6 151.2 47.2 15.4 2.2 15.7 0.4 1.4 24.5 3.1 0.1 2.2 0.1 46.7 136.6 0.0 43.0 1.3 5.0 12.1 15.9 8.1 0.3 3.0 11.3 1.5 0.1 84.4 3.5 0.0 5.5 2.7 0.4 1.0 0.0 0.4 0.6 0.0 1.6 0.0 0.1 11.7 0.1 0.9 6.1 16.5 4.3 0.6 0.8 2.2 2.7 7.9 47.6 7.4 0.0 41.7 5.8 3.7 61.1 0.6 1.4 0.1 0.6 0.4 15.2 0.3 0.2 0.2 2.3 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 91.7 79.4 76.7 59.4 58.9 103.4 81.6 87.9 74.2 88.3 151.2 103.4 19.2 36.1 5.9 2.8 6.5 19.1 5.2 12.0 7.6 40.4 59.4 3.6 44.3 14.2 53.3 4.2 275.1 1.4 24.2 7.9 82.0 0.6 16.0 46.2 142.7 12.5 2.7 0.5 65.0 99.2 28.3 16.8 17.7 1.3 2.0 8.2 49.4 22.8 15.2 1.5 8.9 6.1 1.0 4.3 4.0 34.2 1.1 24.9 18.7 2.6 52.1 0.0 13.0 48.7 48.0 11.0 59.0 2.6 21.5 0.8 5.4 10.7 4.3 6.6 62.4 17.2 0.8 2.1 11.9 8.5 290.3 1.3 6.3 10.4 14.9 ZC3H13 "DKFZp434D1812, KIAA0853, Xio" ENSG00000123200 "Zinc finger CCCH-type containing 13" Q5T200 13 45954465-46052759 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 166.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039340, HPA040140, HPA047806" Uncertain Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane, Actin filaments" "HPA039340: AB_2676454, HPA040140: AB_2676858, HPA047806: AB_2680161" "unprognostic (1.50e-1)" "unprognostic (6.28e-3)" "unprognostic (1.25e-1)" "unprognostic (2.22e-2)" "unprognostic (7.53e-2)" "unprognostic (1.24e-1)" "unprognostic (2.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.77e-1)" "unprognostic (1.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.69e-4)" "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (3.45e-1)" "unprognostic (9.21e-3)" 15.4 10.1 21.9 13.4 26.9 15.0 15.9 16.9 22.0 14.8 6.7 15.0 9.3 18.5 15.3 10.7 12.0 11.4 11.7 17.4 24.9 12.7 58.6 12.6 15.9 18.4 24.2 17.7 9.4 17.7 9.1 15.5 20.4 15.6 12.3 15.7 12.5 14.3 16.0 13.8 11.7 14.6 17.9 16.4 12.0 11.4 25.2 22.5 17.5 15.8 13.1 12.9 11.0 27.3 16.6 20.9 51.1 19.9 36.0 36.6 21.4 29.9 24.5 24.1 15.9 32.3 28.9 46.4 18.8 31.9 16.6 29.0 32.1 25.0 38.4 41.4 32.5 53.3 21.0 28.2 21.2 68.5 28.3 28.2 20.4 25.5 30.0 22.9 26.6 26.5 29.1 13.8 25.6 21.6 34.8 34.7 46.2 31.7 13.4 34.9 33.1 14.2 19.9 25.4 13.4 30.4 29.6 19.0 166.2 33.6 14.7 32.0 44.7 21.5 19.3 19.6 26.3 13.8 17.2 45.5 24.5 35.9 27.8 15.3 4.6 10.5 7.4 5.7 7.4 5.4 5.2 5.8 4.6 5.1 5.1 4.6 7.7 8.8 6.9 7.9 6.3 3.9 21.9 26.9 16.9 22.0 17.4 24.9 18.4 24.2 20.4 17.9 25.2 27.3 79.1 214.7 186.1 37.5 70.9 40.7 65.6 44.2 34.7 84.6 47.3 63.5 164.0 90.1 89.0 55.2 43.8 88.3 75.8 43.6 27.4 64.5 4.2 67.0 114.7 82.7 55.6 117.6 69.4 48.6 78.6 76.2 29.6 79.8 129.3 64.1 75.7 269.2 63.5 85.8 71.2 42.4 40.7 82.5 31.4 11.8 76.7 66.0 28.4 48.7 90.2 87.1 112.3 55.3 149.5 54.7 38.7 81.6 44.0 60.9 34.4 19.5 83.9 69.2 52.6 120.2 99.4 183.6 106.0 37.7 50.6 80.3 80.8 66.9 49.7 54.5 ZHX1 ENSG00000165156 "Zinc fingers and homeoboxes 1" Q9UKY1 8 123248451-123275541 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055357 Supported Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA055357: AB_2682793" "unprognostic (4.36e-3)" "unprognostic (6.73e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (6.09e-4)" "unprognostic (8.73e-3)" "unprognostic (5.61e-2)" "unprognostic (9.22e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (6.00e-2)" "unprognostic (7.97e-2)" "unprognostic (1.44e-1)" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (1.76e-2)" 28.2 14.8 24.5 12.1 24.3 13.5 18.7 27.0 28.1 20.8 21.3 15.6 18.4 17.4 15.2 37.0 18.5 15.1 15.2 23.3 31.9 22.9 39.5 14.4 12.6 25.4 27.7 20.8 17.2 22.8 12.7 14.3 26.5 17.9 14.8 35.0 17.4 18.6 15.5 27.8 19.3 19.2 23.1 15.8 14.8 10.1 24.1 19.8 37.7 19.4 15.0 19.8 17.9 29.4 29.7 13.2 18.0 21.3 34.3 28.3 11.6 35.3 19.6 25.6 29.6 23.5 12.4 44.7 46.1 42.8 11.4 19.6 51.3 32.5 32.4 89.5 26.5 72.6 29.1 14.2 23.3 26.9 33.3 21.4 36.9 35.1 30.0 21.9 20.5 21.2 86.0 34.1 38.3 89.7 62.0 12.1 4.8 62.1 27.7 31.3 16.2 32.0 22.9 66.0 86.3 32.1 40.3 113.6 14.1 10.5 45.4 30.6 19.3 40.1 53.4 32.6 23.8 32.1 95.1 49.6 27.2 49.7 11.2 1.5 3.6 3.6 3.8 6.4 4.8 3.3 4.8 3.5 4.9 3.9 4.5 4.8 1.3 6.5 14.0 2.7 5.7 2.9 24.5 24.3 27.0 28.1 23.3 31.9 25.4 27.7 26.5 23.1 24.1 29.4 35.0 25.6 25.7 0.0 15.7 37.1 28.0 19.7 47.3 46.3 28.8 27.1 30.7 25.8 26.8 20.2 47.9 10.4 22.8 33.5 31.3 16.6 10.9 13.0 52.5 30.8 43.3 19.8 0.0 22.3 6.6 33.0 19.4 13.8 28.5 19.1 28.9 71.5 15.0 146.4 0.0 23.1 14.2 24.2 19.0 21.7 46.6 19.4 26.6 0.0 20.5 46.3 27.8 0.0 0.0 16.7 25.8 64.3 15.3 21.2 35.8 33.2 21.4 34.3 39.5 34.4 38.0 38.5 27.6 84.4 62.5 9.6 20.0 27.0 22.8 29.2 ZKSCAN1 "KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33" ENSG00000106261 "Zinc finger with KRAB and SCAN domains 1" P17029 7 100015572-100041689 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 272.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006672 Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 15: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear bodies" "Nucleoplasm, Mitochondria" "HPA006672: AB_1080707" "unprognostic (2.58e-1)" "unprognostic (1.59e-2)" "unprognostic (3.57e-2)" "unprognostic (4.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.24e-2)" "unprognostic (1.47e-2)" "unprognostic (4.76e-3)" "unprognostic (3.24e-2)" "unprognostic (1.86e-2)" "unprognostic (6.34e-3)" "unprognostic (8.59e-2)" "unprognostic (1.27e-3)" "unprognostic (7.75e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "unprognostic (9.09e-3)" 12.0 18.4 20.2 11.6 29.1 8.7 22.7 17.2 22.1 16.4 7.4 21.5 18.2 15.5 17.1 18.8 21.7 13.9 10.1 14.4 23.8 13.3 52.8 10.9 11.7 21.3 23.2 19.0 26.1 16.5 10.9 11.0 23.4 23.0 23.5 15.8 25.3 10.8 10.4 32.6 16.9 13.7 13.9 13.5 32.6 11.1 24.1 14.2 11.9 8.8 11.9 12.2 17.4 37.5 17.0 12.3 31.8 34.6 32.0 38.7 12.0 18.6 22.5 10.9 11.0 7.4 15.7 19.1 23.0 20.9 19.1 13.7 18.4 16.1 20.6 18.4 11.3 15.5 15.8 19.3 18.0 29.9 17.7 26.1 25.1 14.7 49.0 29.5 24.4 22.2 36.2 16.3 21.7 22.4 28.4 17.6 12.8 31.6 15.2 16.7 16.2 17.3 18.2 26.4 36.8 44.0 28.9 37.4 32.4 17.8 19.1 19.6 36.8 23.7 23.0 27.9 18.9 18.7 35.3 19.5 16.2 20.8 31.7 16.0 4.0 4.1 5.0 3.1 4.9 3.8 3.9 4.9 5.8 4.8 5.3 3.9 4.2 8.8 9.0 3.9 3.5 3.8 20.2 29.1 17.2 22.1 14.4 23.8 21.3 23.2 23.4 13.9 24.1 37.5 45.3 25.6 55.4 57.5 37.0 15.0 45.7 43.4 71.7 93.9 77.6 38.7 42.8 140.2 61.4 46.0 150.1 41.1 40.1 84.8 15.6 55.9 46.5 89.2 90.9 52.2 220.9 24.6 70.1 43.8 15.3 47.9 103.5 68.0 35.4 120.5 44.6 140.8 19.8 89.2 77.7 99.2 77.3 32.7 18.6 18.4 51.3 31.2 40.9 62.8 45.8 61.2 34.0 102.1 272.5 46.6 81.3 53.4 27.1 93.1 70.4 32.4 153.6 70.1 19.7 87.4 43.9 32.8 16.7 62.9 21.5 65.9 32.3 74.0 114.4 62.0 ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 14.7" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: AB_2221026" "unprognostic (5.55e-3)" "unprognostic (2.24e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (3.82e-2)" "unprognostic (2.47e-3)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-3)" "unprognostic (5.00e-2)" "unprognostic (7.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-3)" "unprognostic (1.07e-1)" 1.2 1.5 1.4 1.3 1.7 0.7 1.1 2.9 1.6 1.7 1.0 1.5 1.2 1.5 0.8 1.8 1.3 0.7 1.2 1.3 1.4 1.3 2.4 1.1 1.2 1.4 1.2 1.5 1.4 1.6 2.6 1.2 1.4 1.4 0.9 0.8 1.2 1.0 1.1 2.3 1.3 1.2 0.8 1.4 1.4 1.2 1.2 1.1 1.3 1.0 1.4 1.5 1.5 2.8 2.4 4.2 2.3 3.5 2.6 1.6 2.4 2.0 1.0 1.2 1.1 2.3 1.7 1.9 1.3 1.6 1.5 1.8 3.3 2.2 1.3 3.0 14.7 4.1 4.2 2.1 2.1 3.3 4.2 1.8 2.2 2.6 2.7 2.2 1.8 1.9 4.1 3.6 2.1 1.9 1.6 1.5 2.0 3.0 4.8 2.2 3.6 3.3 1.2 3.1 3.6 2.6 3.0 4.0 2.0 1.8 1.9 2.3 1.8 6.5 1.9 1.6 3.5 3.6 5.3 1.4 2.6 2.2 2.3 0.0 0.8 1.0 2.0 0.7 1.3 0.8 1.1 1.6 1.1 1.0 0.9 1.0 0.2 1.2 0.9 0.5 0.9 1.0 1.4 1.7 2.9 1.6 1.3 1.4 1.4 1.2 1.4 0.8 1.2 2.8 1.1 0.0 4.1 1.6 1.5 1.8 0.6 1.0 0.0 0.7 1.3 0.9 0.6 1.5 1.6 1.8 0.0 0.9 0.8 0.4 1.9 0.9 0.3 1.1 1.2 0.9 0.0 1.7 2.1 0.6 0.9 1.1 1.1 1.6 0.0 1.1 0.0 1.3 0.5 1.7 2.1 0.5 0.0 0.8 0.8 0.0 2.1 2.3 1.8 0.0 1.3 0.5 0.0 1.0 2.2 1.1 1.6 0.4 1.1 0.9 0.8 0.6 1.1 0.7 0.0 1.7 0.8 4.3 1.9 1.1 3.7 0.7 1.2 0.9 1.0 0.4