Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ADGRE1 "EMR1, TM7LN3" ENSG00000174837 "Adhesion G protein-coupled receptor E1" Q14246 19 6887566-6940459 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.8;lymphoid tissue: 14.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 31.5;Macrophages: 13.2;monocytes: 13.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 166.4;eosinophil: 324.9" "Group enriched" "Detected in many" 18 "granulocytes: 324.9;monocytes: 105.0" "Cell line enhanced" "Detected in some" "A549: 7.9;BJ hTERT+: 10.5;GAMG: 10.9;HDLM-2: 26.5;HMC-1: 18.1;Karpas-707: 22.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA052809 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA052809: AB_2681959" "unprognostic (2.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.32e-1)" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (6.93e-5)" "unprognostic (6.77e-2)" "unprognostic (1.18e-1)" "unprognostic (5.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-7)" "unprognostic (6.69e-2)" "unprognostic (3.33e-4)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" 1.9 0.1 0.3 7.3 0.3 6.8 0.2 0.2 0.7 0.1 0.4 0.9 2.9 0.2 1.1 0.1 0.2 1.0 0.2 0.2 0.7 0.3 2.6 4.6 1.5 1.3 0.9 0.0 0.1 0.2 0.1 1.3 0.7 0.2 0.7 0.0 0.2 0.1 0.1 0.0 2.9 1.9 0.5 14.8 1.0 0.9 0.3 3.4 0.1 0.1 1.5 4.0 0.0 0.9 2.8 7.9 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.2 0.2 0.0 0.0 10.9 0.0 0.0 0.0 0.0 26.5 0.0 0.1 0.0 0.0 0.0 0.6 18.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 22.3 0.0 0.2 0.7 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 0.3 0.4 0.2 1.1 4.2 0.1 5.1 5.2 0.0 166.4 21.1 324.9 0.1 58.6 0.3 0.1 7.2 0.9 12.0 0.1 8.9 0.6 7.9 0.9 105.0 0.5 2.2 10.0 0.3 0.3 0.2 0.7 0.2 0.7 1.3 0.9 0.7 0.5 0.3 0.9 0.0 3.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.8 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.3 1.8 0.0 0.6 0.0 0.0 31.5 0.0 0.4 0.0 13.2 0.0 0.0 13.2 0.0 1.0 0.5 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 1.3 0.0 0.0 0.1 0.8 0.1 0.0 0.1 ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732392-14778560 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.4" "Group enriched" "Detected in many" 4 "granulocytes: 47.9;Kupffer cells: 69.4;Macrophages: 73.2;monocytes: 49.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 70.0;eosinophil: 74.7;intermediate monocyte: 46.9;neutrophil: 55.7;non-classical monocyte: 89.9" "Group enriched" "Detected in many" 9 "granulocytes: 74.7;monocytes: 89.9" "Cell line enhanced" "Detected in many" "HEL: 11.8;HMC-1: 18.3;NB-4: 11.5;RPMI-8226: 8.4;U-937: 14.9" "Low region specificity" "Detected in many" HPA055200 Uncertain Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles Cytosol "HPA055200: " "unprognostic (2.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (9.10e-2)" "unprognostic (3.58e-2)" "unprognostic (2.77e-2)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.32e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.35e-6)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.01e-1)" 4.9 1.5 1.0 19.4 1.3 6.9 1.8 1.2 2.1 0.9 1.3 1.4 1.9 0.7 0.7 0.9 0.9 2.5 0.5 1.0 1.5 2.1 2.0 4.2 3.0 2.5 1.6 0.1 0.8 1.1 0.5 1.6 2.2 1.1 1.9 0.6 1.0 2.8 0.6 2.0 2.3 1.6 1.1 15.6 1.5 0.4 1.8 2.4 0.6 0.9 2.2 5.4 0.9 2.4 0.3 1.2 0.1 0.2 0.0 0.3 1.2 0.9 1.3 0.0 0.0 0.2 0.2 0.1 0.1 0.7 2.3 1.9 0.3 0.1 0.0 0.2 0.2 11.8 3.8 0.2 0.5 4.3 18.3 0.9 1.6 4.1 0.6 0.1 0.1 1.0 2.7 0.4 1.3 0.5 1.5 11.5 0.4 0.8 0.2 0.1 1.5 8.4 0.0 0.3 0.0 0.2 2.4 2.0 0.4 0.2 0.3 5.4 0.3 0.3 0.2 0.2 0.1 0.2 0.1 0.2 1.1 14.9 0.6 70.0 13.9 74.7 0.2 46.9 0.2 0.2 0.2 0.1 9.3 0.3 0.1 0.2 55.7 3.3 89.9 1.9 0.1 7.3 1.0 1.3 1.2 2.1 1.0 1.5 2.5 1.6 2.2 1.1 1.8 2.4 0.6 3.2 7.7 0.7 1.9 0.0 4.8 0.0 0.6 0.8 1.6 1.5 0.8 0.0 2.5 0.0 0.0 0.2 12.8 0.0 0.0 0.0 2.0 0.7 3.5 1.8 1.2 3.8 0.9 0.0 0.5 1.9 1.1 0.9 47.9 0.1 0.7 0.5 12.8 0.0 1.2 0.1 0.0 69.4 0.0 2.5 0.0 73.2 0.0 0.0 49.2 0.0 2.1 0.5 12.0 0.0 0.2 0.4 2.1 2.4 0.1 0.1 2.2 0.9 0.0 2.0 1.5 0.3 0.5 0.6 0.0 0.4 3.0 0.1 0.1 3.0 ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.1;lymphoid tissue: 6.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.4;Astrocytes: 2.0;Excitatory neurons: 1.9;granulocytes: 2.5;Inhibitory neurons: 2.4;Macrophages: 8.0;Microglial cells: 3.7;monocytes: 3.2;Oligodendrocytes: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 281.6;eosinophil: 509.0;neutrophil: 489.4" "Lineage enriched" "Detected in many" 8 "granulocytes: 509.0" "Cell line enriched" "Detected in some" 36 "HMC-1: 43.3" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA015638: AB_1848039" "unprognostic (2.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (9.61e-2)" "unprognostic (9.11e-4)" "unprognostic (4.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" 1.2 0.1 0.0 6.1 0.0 3.1 0.0 0.0 0.5 0.2 0.0 0.4 1.6 0.1 0.0 0.3 0.3 1.0 0.1 0.0 0.0 0.1 0.6 2.5 0.3 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.2 0.2 0.5 0.0 1.8 0.0 0.0 0.0 2.3 0.7 0.0 5.9 0.5 0.1 0.1 0.4 0.1 1.0 2.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 281.6 21.8 509.0 0.0 52.9 0.1 0.6 0.2 0.0 5.3 0.1 0.1 0.1 489.4 0.0 61.3 0.3 0.1 7.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 2.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.5 0.0 2.5 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.6 0.0 0.0 0.0 8.0 0.0 3.7 3.2 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 22 "Hofbauer cells: 1777.1;Kupffer cells: 2140.2;Langerhans cells: 1359.1;Macrophages: 1494.0;monocytes: 1022.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Group enriched" "Detected in some" 4 "HEL: 204.6;HMC-1: 329.6;NB-4: 264.7;THP-1: 184.2;U-937: 114.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" 79.6 46.6 24.9 182.3 25.5 235.0 47.2 26.6 33.0 29.3 32.2 48.3 36.4 17.1 12.1 18.7 19.7 61.3 21.1 25.0 31.3 74.3 81.2 99.3 116.8 45.1 36.4 14.4 12.4 12.9 17.3 109.5 36.8 22.3 57.2 3.9 20.3 24.0 6.1 11.7 44.5 74.7 34.3 346.6 22.2 8.7 32.1 69.1 13.8 16.6 57.1 95.3 13.5 42.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 204.6 0.0 0.0 0.0 30.0 329.6 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.9 0.2 0.0 0.0 2.3 264.7 0.4 0.0 0.0 35.9 0.4 8.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 184.2 0.1 0.0 0.2 0.1 0.3 0.2 0.0 1.3 0.2 114.6 0.0 33.1 3823.3 177.9 10.2 6550.1 12.7 57.5 10.8 9.3 2043.3 6.3 33.1 26.2 2943.0 14.5 7744.5 144.2 10.7 4449.8 24.9 25.5 26.6 33.0 25.0 31.3 45.1 36.4 36.8 34.3 32.1 42.7 12.0 25.6 59.6 0.0 39.2 32.5 0.7 0.0 0.6 0.1 5.3 24.3 7.5 18.6 19.2 42.3 0.0 11.1 31.2 1.0 0.0 0.3 1.9 0.6 0.7 28.7 1.2 65.0 0.0 0.4 15.4 20.6 0.5 0.4 68.3 0.4 35.3 13.4 1777.1 0.0 0.0 0.1 0.0 2140.2 1359.1 4.9 7.5 1494.0 39.2 10.3 1022.6 0.0 32.0 0.5 0.1 0.2 11.1 0.7 7.2 0.4 0.3 4.2 10.2 0.1 52.6 4.7 6.5 0.5 1.5 2.1 28.3 22.7 46.1 1.9 0.6 0.3 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 APOBR "APOB100R, APOB48R" ENSG00000184730 "Apolipoprotein B receptor" Q0VD83 16 28494643-28498970 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 34.9;intestine: 26.3;lung: 11.6;lymphoid tissue: 36.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 149.9;granulocytes: 39.3;Intestinal goblet cells: 47.5;NK-cells: 65.9;Paneth cells: 84.8;Undifferentiated cells: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 41.6;HMC-1: 124.8;NB-4: 35.7;THP-1: 25.8;U-937: 30.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041667, HPA042093" Enhanced NA NA 700000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041667: AB_10793972, HPA042093: AB_10795393" "unprognostic (3.16e-1)" "unprognostic (8.01e-3)" "unprognostic (6.19e-3)" "prognostic favorable (3.26e-4)" "unprognostic (5.48e-2)" "unprognostic (4.79e-3)" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-2)" "unprognostic (7.60e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.25e-2)" 3.3 2.0 0.9 20.0 0.9 34.9 1.6 1.1 2.0 1.3 0.9 26.3 6.1 1.1 1.4 1.6 2.4 2.8 1.3 0.9 1.7 1.1 2.7 11.6 6.7 2.3 1.3 0.4 1.3 0.6 0.7 2.7 1.8 1.8 16.1 0.1 2.1 3.5 1.1 3.1 9.4 2.7 1.5 36.6 4.1 1.3 2.6 3.7 1.2 1.1 3.8 4.8 1.1 2.2 0.1 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.2 2.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 41.6 0.3 0.5 0.0 15.4 124.8 0.0 0.1 0.0 0.0 0.1 0.0 0.4 1.3 0.7 0.0 1.2 1.5 35.7 0.0 0.0 0.0 0.9 0.1 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.1 0.1 1.4 25.8 0.1 0.0 0.0 0.1 0.0 0.7 0.3 1.5 0.1 30.8 0.1 10.5 5.8 16.5 2.4 2.9 2.3 0.0 1.3 2.4 5.0 0.1 0.3 1.2 17.1 7.3 2.6 0.9 0.4 2.3 0.9 0.9 1.1 2.0 0.9 1.7 2.3 1.3 1.8 1.5 2.6 2.2 0.3 3.2 7.7 0.0 2.2 0.8 0.2 0.1 0.0 0.0 2.2 0.6 0.6 0.0 2.7 3.7 0.0 2.1 21.9 149.9 0.0 0.0 0.1 0.2 0.2 0.7 9.1 6.5 0.0 0.2 14.6 1.0 1.1 0.2 39.3 0.1 0.7 0.6 32.3 0.0 0.0 47.5 0.0 30.1 32.5 0.4 0.3 33.9 1.8 1.9 34.8 0.0 65.9 0.0 0.1 0.0 84.8 0.0 5.7 0.1 6.5 0.1 0.8 0.0 6.6 0.0 0.4 0.4 0.3 0.0 0.3 5.9 16.0 0.0 49.3 0.4 ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 36000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: AB_2686262" "unprognostic (3.60e-2)" "unprognostic (7.68e-2)" "unprognostic (6.19e-2)" "unprognostic (5.98e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (4.01e-2)" "unprognostic (4.07e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-5)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "prognostic favorable (6.41e-4)" "unprognostic (7.56e-3)" 41.5 63.5 40.0 58.6 48.6 97.5 33.4 37.9 50.4 44.1 62.9 35.5 29.6 38.9 14.0 37.7 48.3 44.2 42.9 42.2 38.5 47.8 40.2 71.8 53.4 50.6 42.3 49.4 37.1 20.4 48.9 35.5 45.9 44.9 18.2 8.6 33.3 25.7 20.1 47.1 43.3 28.7 40.1 117.5 31.3 16.4 50.8 32.2 46.6 20.1 25.2 39.7 37.5 56.8 19.7 41.9 15.2 18.5 63.4 42.9 23.1 26.2 46.5 29.8 29.3 56.0 50.8 42.9 51.3 44.4 40.7 64.5 23.2 64.4 12.5 50.9 28.4 36.6 40.3 81.9 43.7 25.1 98.7 47.5 65.4 48.7 23.4 36.2 33.2 31.3 31.5 17.4 13.9 40.3 38.9 89.3 9.5 35.1 25.9 36.8 23.2 21.3 27.5 61.1 15.7 32.0 19.1 27.9 84.8 19.5 25.1 56.8 37.5 41.0 28.5 42.8 16.4 27.4 14.3 23.0 21.8 37.4 22.3 19.3 24.8 30.7 8.9 39.4 5.2 6.6 5.9 6.8 15.9 4.7 4.5 5.4 50.8 13.4 51.3 5.3 6.7 17.6 40.0 48.6 37.9 50.4 42.2 38.5 50.6 42.3 45.9 40.1 50.8 56.8 8.9 28.9 32.3 33.6 16.1 7.4 7.5 14.3 15.4 4.3 8.7 7.9 2.6 7.2 9.0 16.5 33.3 9.2 18.3 16.5 9.8 13.5 50.1 14.1 11.7 7.8 23.3 9.9 7.7 7.5 8.9 22.4 16.3 9.1 10.8 36.9 9.7 10.8 43.0 0.0 7.0 12.8 12.2 45.6 25.1 6.4 20.8 57.3 8.8 30.0 29.0 7.4 21.6 17.6 31.5 12.1 10.9 15.1 12.3 4.8 20.9 5.3 20.2 2.8 0.0 8.6 8.8 0.4 2.8 10.8 5.4 4.9 12.4 10.5 15.1 7.4 ARHGAP4 "C1, KIAA0131, p115, RhoGAP4, SrGAP4" ENSG00000089820 "Rho GTPase activating protein 4" P98171 X 153907367-153934999 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 119.1;lymphoid tissue: 120.9" "Cell type enhanced" "Detected in many" "B-cells: 65.3;dendritic cells: 70.0;Hofbauer cells: 86.6;Kupffer cells: 77.2;Macrophages: 76.0;NK-cells: 70.0;T-cells: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 103.0;HL-60: 76.7;Karpas-707: 90.8;MOLT-4: 93.0;RPMI-8226: 180.7;THP-1: 83.7;U-698: 90.4;U-937: 79.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA000301, HPA001012, HPA001083" Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA000301: , HPA001012: AB_1078201, HPA001083: AB_1078199" "unprognostic (3.54e-2)" "prognostic favorable (3.94e-5)" "prognostic unfavorable (1.97e-5)" "unprognostic (5.79e-2)" "unprognostic (9.42e-2)" "prognostic favorable (3.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.39e-1)" "unprognostic (3.27e-1)" "unprognostic (1.37e-1)" "unprognostic (7.81e-3)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (8.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" 20.0 12.5 5.2 52.2 5.4 119.1 13.4 6.9 6.5 9.9 15.0 18.6 14.2 9.7 3.1 7.0 12.9 14.4 10.3 5.7 6.3 22.6 8.6 36.2 73.8 10.9 8.3 5.4 5.9 1.7 8.6 21.2 9.3 11.1 6.9 1.2 9.2 3.8 4.3 5.0 49.7 6.5 8.2 120.9 12.6 7.2 8.5 42.7 10.9 1.5 33.7 11.6 9.2 10.0 1.5 0.6 1.0 5.9 0.2 0.0 2.5 1.0 0.4 0.1 0.2 0.4 42.8 103.0 5.9 0.1 0.8 1.2 4.6 0.2 0.0 27.8 3.4 44.4 0.5 1.7 3.6 76.7 59.7 0.2 0.4 0.0 0.3 0.5 9.1 22.4 0.5 90.8 0.5 4.6 93.0 1.5 3.7 0.4 0.3 44.6 12.0 180.7 0.4 0.7 8.4 12.1 0.9 2.1 0.9 1.2 19.0 83.7 1.9 0.3 1.3 0.9 0.5 60.1 55.8 90.4 0.7 79.9 0.2 10.9 26.1 35.4 26.2 42.4 18.6 18.0 18.8 21.1 25.5 16.9 17.4 17.4 22.4 16.0 59.4 31.6 23.5 26.1 5.2 5.4 6.9 6.5 5.7 6.3 10.9 8.3 9.3 8.2 8.5 10.0 16.0 9.6 22.7 2.6 65.3 3.4 0.6 0.2 0.0 13.7 2.4 6.1 48.3 1.5 2.7 18.4 4.2 1.9 70.0 9.5 5.9 0.9 0.1 2.4 1.4 13.0 4.8 11.3 2.1 0.6 1.9 3.5 7.1 1.5 34.2 7.7 4.2 0.5 86.6 3.3 1.4 6.6 0.0 77.2 31.5 0.2 0.9 76.0 10.6 19.7 42.5 1.9 70.0 2.0 0.7 0.2 0.5 0.0 32.9 0.5 3.0 0.8 8.7 4.6 0.0 7.1 2.6 0.7 5.2 1.6 1.7 1.4 69.5 1.1 5.0 0.4 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "dendritic cells: 171.0;Early spermatids: 96.8;NK-cells: 123.6;Spermatocytes: 89.0;T-cells: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 388.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 27.6;HMC-1: 116.2;MOLT-4: 22.5;NB-4: 22.1;THP-1: 34.9;U-937: 27.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (1.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.91e-2)" "prognostic favorable (6.61e-5)" "unprognostic (1.24e-1)" "unprognostic (2.38e-3)" "unprognostic (4.79e-2)" "unprognostic (5.56e-3)" "unprognostic (1.28e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.90e-9)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" 10.8 4.2 4.2 34.3 6.1 119.7 4.1 8.1 11.1 2.6 4.7 7.7 8.2 3.4 1.6 4.6 7.4 10.5 3.9 4.4 5.3 5.1 7.5 22.0 56.9 7.8 5.8 1.6 3.5 0.6 2.2 5.2 8.8 4.3 10.7 0.5 4.7 1.8 1.3 2.2 37.6 5.9 5.6 100.7 8.8 19.3 6.1 34.9 4.5 6.4 60.7 9.5 3.6 6.4 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.4 0.5 0.1 0.2 0.1 0.0 14.3 0.3 0.3 0.0 0.2 0.4 0.0 0.0 0.7 0.0 27.6 0.1 0.0 1.1 16.4 116.2 0.7 0.0 0.0 0.3 0.2 0.0 14.3 0.5 7.9 0.0 0.0 22.5 22.1 1.0 0.0 0.0 9.1 10.2 4.6 0.0 0.1 3.9 3.0 0.0 0.0 0.4 0.5 0.0 34.9 0.9 0.2 0.3 0.1 0.1 9.2 7.2 13.3 0.3 27.3 0.5 51.9 86.1 243.4 43.3 89.2 30.0 35.9 47.3 39.6 72.1 44.0 61.9 46.0 388.9 68.2 71.0 97.4 63.6 70.8 4.2 6.1 8.1 11.1 4.4 5.3 7.8 5.8 8.8 5.6 6.1 6.4 2.2 0.0 14.2 1.0 49.1 1.5 0.2 0.0 1.8 0.2 1.6 2.9 2.1 1.5 1.3 0.0 2.1 0.4 171.0 0.6 0.0 0.2 96.8 0.6 0.8 1.5 0.0 11.6 3.7 0.0 0.6 2.4 4.6 0.8 12.0 0.0 3.6 1.2 43.5 0.0 1.9 0.5 0.0 39.0 19.7 44.8 1.8 35.1 0.0 8.4 34.8 0.0 123.6 0.0 0.2 0.2 0.1 0.0 50.8 0.2 0.0 0.3 2.2 0.7 0.0 0.6 1.2 89.0 17.5 0.4 1.4 0.3 108.2 0.3 0.4 0.1 ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.4" "Cell type enhanced" "Detected in all" "dendritic cells: 156.2;NK-cells: 187.4;T-cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB009502: AB_667785, HPA012924: AB_1845000, HPA060784: AB_2684363" "prognostic favorable (5.92e-4)" "unprognostic (2.09e-1)" "unprognostic (8.29e-3)" "unprognostic (8.10e-3)" "unprognostic (7.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.29e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (3.54e-1)" "unprognostic (1.95e-1)" "unprognostic (8.00e-2)" "unprognostic (4.65e-2)" 50.2 20.9 17.1 79.1 21.8 113.5 39.9 19.1 21.9 37.2 17.8 37.5 26.8 33.4 3.6 34.1 36.4 23.5 26.2 16.1 18.2 31.9 30.0 67.7 127.5 24.1 20.2 32.9 27.4 12.6 25.9 18.3 22.0 32.1 10.4 5.6 28.8 11.8 15.4 37.6 87.1 13.4 19.0 168.4 34.9 10.9 21.4 96.5 36.7 8.9 48.9 33.9 33.2 27.9 58.8 69.9 15.8 19.9 21.9 22.9 18.4 30.1 45.7 37.4 32.8 21.5 49.2 77.9 54.6 27.8 19.8 33.8 20.3 46.9 11.8 74.1 23.6 63.1 30.6 28.4 31.9 68.4 100.8 27.8 30.5 36.3 23.5 19.9 36.2 68.2 25.5 46.7 21.8 40.4 48.0 52.9 17.9 46.4 54.0 71.8 29.7 46.3 23.2 31.8 10.3 43.8 42.3 18.7 36.0 8.1 21.9 114.4 49.6 49.7 33.2 26.8 47.7 63.0 43.2 68.4 40.5 107.6 80.2 10.4 20.5 29.2 47.0 39.5 37.2 20.1 35.6 49.4 21.5 19.5 36.1 39.4 27.4 32.1 57.5 11.3 38.7 36.4 17.1 21.8 19.1 21.9 16.1 18.2 24.1 20.2 22.0 19.0 21.4 27.9 46.6 6.4 22.0 35.3 97.3 14.5 13.9 15.0 20.5 18.7 13.1 12.4 4.2 8.6 8.8 7.3 27.1 13.3 156.2 21.7 3.9 23.6 1.4 12.2 16.7 29.0 21.7 23.8 8.0 24.9 22.8 17.7 56.6 16.8 31.7 19.3 26.7 9.3 38.2 11.8 7.9 29.2 16.2 52.5 31.9 1.8 19.3 58.9 19.6 18.7 39.0 8.8 187.4 13.6 27.6 55.9 22.7 16.6 66.4 15.7 10.1 7.3 6.3 19.1 26.3 17.6 17.3 7.3 10.1 17.3 14.8 10.1 159.0 20.4 26.4 11.1 ATG16L2 "ATG16B, FLJ00012, WDR80" ENSG00000168010 "Autophagy related 16 like 2" Q8NAA4 11 72814406-72843674 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 136.8;lymphoid tissue: 129.0" "Cell type enhanced" "Detected in many" "Paneth cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 45.4;neutrophil: 59.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045444, HPA050312" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA045444: AB_2679324, HPA050312: AB_2681082" "unprognostic (7.20e-3)" "unprognostic (1.16e-1)" "unprognostic (1.54e-1)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (1.31e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" "prognostic favorable (7.06e-4)" "unprognostic (2.49e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (1.74e-1)" "unprognostic (4.38e-2)" "unprognostic (1.08e-1)" "unprognostic (4.83e-2)" 20.2 18.1 18.1 33.0 19.2 136.8 14.9 20.2 24.1 21.6 16.2 20.4 10.8 14.6 7.5 26.1 22.1 18.9 20.8 18.0 16.0 20.1 18.5 41.2 34.3 18.9 17.7 23.4 15.1 6.3 13.7 10.2 18.0 14.4 17.0 2.9 13.6 8.2 7.7 72.9 34.0 15.0 15.3 129.0 17.7 6.5 21.1 9.7 15.9 7.4 25.2 18.9 22.2 20.9 2.7 2.5 7.5 5.9 8.7 7.2 4.6 6.1 5.9 2.9 4.4 3.1 6.4 18.3 4.0 7.7 5.3 5.2 0.9 20.1 5.0 14.2 3.0 14.5 14.4 5.1 6.4 18.8 58.2 6.9 2.7 6.6 8.0 32.2 9.0 32.7 1.9 24.1 3.4 9.1 22.5 32.0 1.1 12.0 2.9 10.6 5.5 8.6 9.7 9.2 5.5 4.4 2.6 13.2 5.8 5.9 6.6 25.5 12.6 7.9 2.9 14.4 5.0 11.0 2.9 8.1 3.5 16.4 4.5 5.9 16.3 45.4 2.7 9.3 2.7 2.6 3.9 5.4 10.9 4.6 2.2 2.6 59.6 5.2 11.8 1.7 4.0 4.0 18.1 19.2 20.2 24.1 18.0 16.0 18.9 17.7 18.0 15.3 21.1 20.9 19.5 6.4 14.4 11.4 37.6 16.7 5.1 6.1 10.2 3.6 8.7 9.0 5.0 4.3 6.2 5.5 2.1 9.6 29.0 13.0 0.0 5.0 0.8 8.9 12.0 12.7 13.1 9.9 14.0 1.0 3.7 7.1 17.9 7.9 22.9 10.6 18.9 3.8 16.2 5.0 11.1 9.1 8.2 48.5 18.1 2.1 10.2 45.7 3.6 23.4 39.2 4.4 30.9 18.1 9.7 2.7 59.1 7.9 17.3 2.5 8.3 2.5 8.1 3.5 0.0 8.8 11.4 4.9 13.4 15.7 17.3 12.3 21.3 7.2 14.0 6.0 C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "granulocytes: 182.3;Hofbauer cells: 195.3;Kupffer cells: 797.4;Langerhans cells: 226.7;Macrophages: 413.5;monocytes: 278.6;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "HDLM-2: 141.3;HL-60: 70.4;NB-4: 40.3;THP-1: 55.2;U-937: 117.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" 45.4 23.6 16.3 70.8 16.2 115.0 22.3 17.2 29.0 13.2 19.6 15.8 7.3 11.5 6.3 9.8 22.5 31.2 18.1 16.3 18.4 12.5 41.9 85.7 70.4 20.6 17.3 9.4 9.4 4.8 9.1 15.2 19.7 11.7 17.9 9.5 11.2 6.6 10.1 7.8 21.2 37.6 16.7 134.5 12.5 7.6 23.3 27.7 10.0 7.4 55.9 25.1 10.8 21.4 0.3 0.1 0.5 1.1 0.4 0.6 0.6 0.9 0.1 0.3 0.3 0.2 0.4 0.5 0.5 0.2 0.1 0.2 0.8 0.5 0.6 141.3 0.4 0.4 0.5 0.0 0.4 70.4 11.1 0.0 2.6 0.8 0.9 1.0 2.0 0.7 0.5 0.4 0.5 0.5 0.6 40.3 0.2 0.7 0.8 0.1 0.7 0.1 0.3 0.1 0.5 0.2 0.5 0.6 0.8 0.6 0.3 55.2 0.0 0.8 1.0 0.7 0.6 0.6 0.1 0.6 0.3 117.9 1.2 1114.1 1026.8 1294.8 166.6 1529.2 47.6 231.0 206.5 97.3 1021.6 296.4 318.0 193.6 143.3 536.7 1173.4 302.8 66.7 1189.5 16.3 16.2 17.2 29.0 16.3 18.4 20.6 17.3 19.7 16.7 23.3 21.4 4.4 22.4 43.9 8.1 84.1 7.9 0.7 0.4 0.6 4.0 2.2 5.2 3.8 10.0 4.5 7.3 2.1 1.0 103.4 0.6 0.0 0.2 36.7 0.8 0.9 8.1 1.8 23.5 9.2 0.2 2.0 3.2 0.5 1.0 182.3 0.9 15.7 8.9 195.3 0.0 13.0 0.0 0.0 797.4 226.7 90.7 2.8 413.5 12.4 12.2 278.6 0.2 355.3 6.0 7.7 0.2 0.0 0.7 4.2 0.8 0.9 1.0 0.9 4.2 32.9 2.4 2.9 2.4 2.0 0.2 6.5 1.6 59.8 0.3 0.7 0.3 C5AR2 "C5L2, GPR77" ENSG00000134830 "Complement component 5a receptor 2" Q9P296 19 47332175-47347329 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.1" "Cell type enhanced" "Detected in many" "Early spermatids: 14.4;Hepatic stellate cells: 23.9;Kupffer cells: 48.6;Macrophages: 34.5" "Cancer enhanced" "Detected in many" "breast cancer: 3.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 17.8;eosinophil: 11.9;neutrophil: 33.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 33.0" "Group enriched" "Detected in some" 4 "MCF7: 20.7;T-47d: 24.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016629 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 41: Macrophages - Immune response" "HPA016629: AB_1849312" "unprognostic (5.00e-2)" "unprognostic (2.31e-2)" "unprognostic (4.33e-2)" "unprognostic (2.00e-6)" "unprognostic (2.88e-1)" "unprognostic (1.13e-2)" "unprognostic (1.02e-2)" "unprognostic (2.13e-1)" "unprognostic (2.25e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (6.05e-2)" "unprognostic (3.73e-5)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (1.34e-1)" "unprognostic (6.88e-3)" 4.2 1.2 1.1 4.1 0.8 5.8 2.2 1.2 2.9 1.2 1.8 1.3 0.4 0.7 0.4 0.6 2.3 0.7 2.1 2.4 0.5 1.2 1.9 6.5 0.9 1.3 0.7 0.6 0.8 0.1 0.9 2.2 0.7 0.4 0.4 0.4 1.2 0.3 0.3 1.4 1.5 1.0 0.5 14.1 1.1 3.1 0.8 0.3 0.9 0.4 3.2 1.2 1.3 1.3 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.7 0.4 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.1 5.2 0.1 0.0 0.8 1.5 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.4 0.0 20.7 0.1 2.4 0.2 0.0 0.1 0.3 0.1 2.7 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.1 24.8 0.3 0.2 0.8 0.2 0.5 0.1 0.3 0.3 0.9 0.8 1.4 0.1 17.8 2.7 11.9 0.3 2.3 0.4 0.3 0.2 0.2 0.6 0.4 0.2 0.2 33.0 0.3 4.4 0.3 0.6 0.7 1.1 0.8 1.2 2.9 2.4 0.5 1.3 0.7 0.7 0.5 0.8 1.3 0.6 3.2 1.9 0.3 1.1 0.4 2.8 0.1 0.0 1.3 4.7 2.8 1.6 2.8 2.6 1.8 2.1 0.1 1.7 0.0 0.0 0.0 14.4 0.5 0.5 1.7 0.0 3.2 0.6 0.0 0.2 2.1 0.0 1.1 1.3 6.1 23.9 1.2 8.3 0.0 0.1 0.0 0.0 48.6 4.6 3.0 0.0 34.5 0.0 1.0 8.3 0.3 1.0 0.0 0.1 0.0 0.0 0.4 1.3 2.0 0.0 0.3 0.8 4.2 0.0 4.0 1.0 0.2 0.4 0.1 0.9 0.1 1.3 4.1 0.0 1.9 CALHM6 "C6orf187, dJ93H18.5, FAM26F, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5" ENSG00000188820 "Calcium homeostasis modulator family member 6" Q5R3K3 6 116461370-116463771 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 136.6" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 724.6;non-classical monocyte: 861.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 28.0;Karpas-707: 45.1;RPMI-8226: 159.8;U-937: 59.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.14e-2)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (7.15e-3)" "unprognostic (9.53e-3)" "unprognostic (4.10e-2)" "unprognostic (2.69e-1)" "unprognostic (1.68e-1)" "unprognostic (8.19e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (9.31e-10)" "unprognostic (1.69e-1)" "unprognostic (2.12e-2)" "unprognostic (3.85e-3)" "unprognostic (9.25e-3)" 7.4 7.3 4.9 60.2 5.2 41.4 10.0 4.5 6.6 4.3 5.0 10.4 12.2 2.4 3.6 4.1 4.1 7.2 4.3 4.7 5.2 4.1 24.7 10.8 73.0 8.1 4.7 4.5 1.8 1.7 4.8 12.5 5.3 5.4 7.0 1.1 5.7 3.0 1.6 1.9 20.9 11.8 5.6 136.6 7.9 8.2 5.3 14.0 2.4 2.6 23.1 11.4 3.0 5.4 6.4 0.0 0.6 0.4 0.5 2.0 11.7 0.2 1.3 2.0 1.3 0.0 1.0 0.2 3.5 1.5 0.0 0.0 0.3 0.2 4.2 0.7 0.4 28.0 0.0 0.0 2.8 0.1 0.1 2.2 0.0 0.2 0.2 0.5 0.7 0.0 0.0 45.1 5.5 0.0 2.7 4.8 3.6 0.0 0.0 2.4 0.0 159.8 2.2 0.3 2.7 0.1 14.9 0.1 11.7 1.6 0.2 7.3 0.1 0.0 0.2 0.1 0.9 11.4 0.2 0.0 0.3 59.7 3.9 22.0 205.7 50.1 16.6 724.6 16.6 231.8 23.0 15.5 193.8 308.9 28.9 15.2 115.8 27.4 861.9 86.5 2.7 175.6 4.9 5.2 4.5 6.6 4.7 5.2 8.1 4.7 5.3 5.6 5.3 5.4 0.6 0.0 1.7 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 0.0 0.2 0.3 0.8 0.0 0.0 0.0 10.0 9.0 0.7 0.0 0.1 0.0 1.4 0.0 0.0 138.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.2 1.2 1.8 0.0 0.0 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 66.6" "Cell type enhanced" "Detected in many" "dendritic cells: 107.4;NK-cells: 132.8;Plasma cells: 73.4;T-cells: 86.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol No No "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: AB_2667535" "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favorable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 11.5 10.2 1.7 28.6 2.0 66.6 13.9 1.3 2.1 9.6 4.2 16.1 20.5 8.5 13.2 12.9 14.1 13.2 5.2 2.1 1.8 10.7 14.1 19.6 37.7 3.4 3.0 7.7 7.8 2.9 3.4 9.9 2.7 6.9 17.6 4.6 8.4 7.3 3.3 12.1 26.0 9.9 2.4 37.1 15.9 4.3 2.6 24.4 7.9 3.0 29.7 18.0 8.6 2.4 33.6 26.6 7.7 22.2 20.7 29.7 12.0 13.8 13.2 16.0 26.2 36.1 54.9 3.7 29.6 10.7 28.7 16.2 17.2 16.1 31.3 21.1 15.4 31.0 21.9 35.1 17.1 25.6 33.8 25.9 38.0 30.1 23.9 13.4 15.1 26.9 28.6 69.1 14.7 13.1 32.1 25.9 12.6 17.5 23.7 24.7 15.9 55.4 30.8 35.3 2.3 1.1 17.9 29.8 18.0 7.0 8.0 19.1 19.6 17.3 18.0 9.0 10.9 63.1 30.2 21.2 25.3 33.1 16.6 76.1 39.5 77.1 70.7 51.2 66.0 40.9 57.8 75.9 41.6 24.0 37.0 47.2 153.6 70.6 51.5 18.6 75.0 40.6 1.7 2.0 1.3 2.1 2.1 1.8 3.4 3.0 2.7 2.4 2.6 2.4 8.5 25.6 26.7 0.7 50.0 7.5 13.0 6.1 10.2 2.1 12.9 9.3 2.5 10.0 13.0 5.5 10.4 8.5 107.4 37.0 15.6 12.3 5.9 25.6 8.1 10.1 4.2 10.5 2.5 8.4 12.1 9.5 19.4 27.2 24.6 10.4 5.3 11.7 11.9 0.0 1.3 15.2 4.1 25.3 15.7 1.9 2.5 25.0 7.2 10.3 35.6 0.2 132.8 1.0 0.5 11.2 30.1 0.7 73.4 9.7 22.3 23.6 14.2 0.4 0.0 4.5 3.7 0.8 0.4 13.1 7.7 3.4 86.9 10.6 17.4 12.7 CASS4 "C20orf32, HEFL, HEPL" ENSG00000087589 "Cas scaffold protein family member 4" Q9NQ75 20 56412112-56460387 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.2;lymphoid tissue: 9.6" "Cell type enhanced" "Detected in some" "granulocytes: 14.0;Kupffer cells: 8.2;Langerhans cells: 7.1;Macrophages: 12.1;Microglial cells: 29.0;T-cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 23.1;neutrophil: 68.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 68.9" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 7.5;HEL: 13.7;HMC-1: 38.9;K-562: 16.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB034217 Approved NA NA 680000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB034217: AB_2071598" "unprognostic (9.55e-3)" "unprognostic (2.53e-2)" "unprognostic (2.44e-2)" "unprognostic (8.51e-2)" "unprognostic (3.04e-1)" "unprognostic (1.56e-3)" "unprognostic (2.06e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-1)" "unprognostic (4.10e-2)" "unprognostic (5.28e-2)" "unprognostic (6.19e-2)" "unprognostic (7.27e-4)" "unprognostic (5.33e-2)" "unprognostic (3.65e-2)" "unprognostic (6.50e-2)" "unprognostic (8.16e-2)" 1.7 0.9 1.9 9.6 1.9 2.8 0.9 1.6 1.9 1.0 1.7 1.0 1.4 0.5 0.2 0.9 0.6 2.3 0.6 1.6 2.0 0.7 1.7 12.2 3.9 2.6 1.9 1.4 0.4 0.4 0.3 4.5 2.0 0.5 1.0 0.4 0.6 0.4 0.3 0.7 2.1 1.3 1.7 5.6 1.0 0.3 2.0 1.9 0.3 0.5 2.4 2.0 0.4 1.8 0.1 0.1 0.2 0.2 0.0 0.2 0.1 0.7 0.2 0.1 0.3 0.2 2.5 0.2 0.1 7.5 0.2 0.2 0.1 0.0 0.5 0.2 0.2 13.7 0.1 0.9 0.2 0.5 38.9 0.8 0.3 0.2 0.0 0.4 0.0 0.2 16.1 0.2 0.5 0.2 0.3 5.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.1 0.1 0.1 0.1 0.2 0.0 1.7 0.3 0.1 0.2 0.2 0.0 0.3 0.3 0.2 0.1 1.5 0.2 0.7 4.0 23.1 1.3 0.9 2.0 0.1 2.2 2.4 6.9 0.1 4.2 3.8 68.9 2.8 0.1 2.4 1.4 2.6 1.9 1.9 1.6 1.9 1.6 2.0 2.6 1.9 2.0 1.7 2.0 1.8 0.4 0.0 1.1 1.6 0.9 0.1 0.0 0.0 0.6 0.0 0.3 0.3 0.5 0.0 1.8 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.4 1.8 0.0 0.0 1.8 1.5 0.0 14.0 0.0 0.4 1.1 2.2 0.0 1.4 0.0 0.0 8.2 7.1 0.1 0.0 12.1 0.0 29.0 6.5 0.0 5.2 1.5 1.0 0.0 0.0 0.0 4.3 0.1 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.1 0.3 13.1 0.1 0.0 0.0 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CD244 "2B4, NAIL, NKR2B4, Nmrk, SLAMF4" ENSG00000122223 "CD244 molecule" Q9BZW8 1 160830160-160862887 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 16.8" "Cell type enhanced" "Detected in some" "dendritic cells: 28.4;Kupffer cells: 17.7;NK-cells: 66.9;T-cells: 21.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 472.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 472.1" "Cell line enhanced" "Detected in some" "HEL: 20.6;HMC-1: 69.4;NB-4: 14.4;U-937: 28.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 280000 "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.11e-3)" "unprognostic (1.54e-2)" "unprognostic (1.85e-2)" "unprognostic (6.95e-6)" "unprognostic (5.79e-2)" "unprognostic (1.43e-4)" "unprognostic (1.93e-2)" "unprognostic (7.36e-2)" "unprognostic (3.36e-1)" "unprognostic (2.85e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-1)" "unprognostic (5.40e-4)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (1.87e-1)" "unprognostic (1.79e-1)" 2.1 0.4 0.3 3.7 0.4 10.0 0.4 0.3 0.5 0.3 0.3 1.1 3.0 0.3 0.3 0.4 0.5 1.0 0.6 0.4 0.3 0.3 4.2 3.3 3.4 0.4 0.3 1.0 0.1 0.1 0.1 0.4 0.3 0.4 1.4 0.0 1.1 0.4 0.3 0.3 2.8 1.1 0.3 16.8 1.0 2.7 0.3 2.8 0.2 0.2 2.0 1.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.4 6.8 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 2.1 14.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 2.6 1.1 0.1 0.0 28.7 0.0 472.1 43.3 107.9 71.3 59.1 35.2 0.3 3.7 39.7 41.0 0.2 5.3 36.0 3.1 78.5 73.6 2.4 0.2 70.7 0.3 0.4 0.3 0.5 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.4 0.1 3.2 6.1 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.0 5.2 0.0 0.1 0.2 0.0 2.1 0.7 1.7 0.0 0.3 0.5 0.1 3.8 0.0 0.7 0.2 0.6 0.0 0.1 0.0 0.0 17.7 3.1 2.4 1.8 8.3 0.0 0.0 8.5 0.0 66.9 0.0 0.2 0.0 0.0 2.2 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.0 0.1 0.0 21.9 0.5 0.0 0.0 CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 95.2" "Cell type enhanced" "Detected in some" "dendritic cells: 103.5;granulocytes: 59.5;Hofbauer cells: 114.0;Kupffer cells: 97.6;Macrophages: 90.9;NK-cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 104.4;NB-4: 45.9;RPMI-8226: 88.7" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" 10.6 7.5 6.7 31.1 7.1 24.4 4.6 7.1 31.1 2.8 7.5 9.2 11.3 3.5 1.8 3.5 3.1 14.2 4.7 6.9 7.8 3.5 14.6 18.1 27.0 11.4 8.6 1.5 3.2 1.4 3.6 13.9 13.2 4.0 8.6 1.0 4.0 2.5 1.6 4.5 13.5 11.7 9.2 95.2 4.9 1.2 12.1 14.1 2.3 2.7 11.7 9.5 2.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 5.5 104.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.5 45.9 0.0 0.0 0.0 0.2 0.0 88.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 17.1 0.0 845.6 170.3 481.9 226.4 374.2 48.3 18.9 45.5 67.5 159.2 6.4 16.7 52.5 560.5 456.5 387.6 149.7 3.1 197.0 6.7 7.1 7.1 31.1 6.9 7.8 11.4 8.6 13.2 9.2 12.1 12.5 1.0 0.0 7.4 0.3 7.8 0.9 0.1 0.2 0.0 0.0 0.6 1.8 0.6 1.5 0.7 0.0 0.0 0.7 103.5 0.1 0.0 0.1 0.0 0.6 0.2 2.5 0.0 5.7 0.1 0.0 1.2 0.8 0.5 0.7 59.5 0.0 2.2 1.3 114.0 0.0 0.3 0.2 0.0 97.6 24.0 0.4 0.0 90.9 3.6 5.6 36.6 0.0 225.6 1.0 0.0 0.0 0.1 0.0 14.5 0.1 0.0 0.4 0.6 0.1 6.6 0.6 0.5 0.0 0.4 0.2 0.6 1.5 33.2 0.0 0.2 0.2 CD300LF "CD300f, CLM1, IGSF13, IREM1, NKIR" ENSG00000186074 "CD300 molecule like family member f" Q8TDQ1 17 74694311-74712978 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.0;lung: 17.7;lymphoid tissue: 28.9" "Group enriched" "Detected in some" 5 "granulocytes: 22.8;Hofbauer cells: 20.6;Kupffer cells: 33.2;Macrophages: 47.0;monocytes: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 234.2" "Group enriched" "Detected in many" 43 "dendritic cells: 63.8;granulocytes: 234.2;monocytes: 193.0" "Group enriched" "Detected in some" 6 "THP-1: 25.6;U-937: 48.6" "Low region specificity" "Detected in some" HPA013712 Supported NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA013712: AB_2668874" "unprognostic (6.51e-2)" "unprognostic (1.49e-3)" "unprognostic (3.81e-2)" "unprognostic (4.00e-2)" "unprognostic (8.51e-2)" "unprognostic (6.74e-2)" "unprognostic (1.79e-1)" "unprognostic (3.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-1)" "unprognostic (9.60e-2)" "unprognostic (4.14e-2)" "unprognostic (7.75e-2)" "unprognostic (4.79e-2)" 1.9 0.6 0.9 13.5 1.1 27.0 0.8 6.2 4.2 1.3 0.7 3.4 3.8 0.6 0.2 0.5 0.7 2.7 0.5 1.0 1.3 0.6 2.2 17.7 8.8 2.6 1.8 0.2 0.5 0.4 0.4 1.7 2.4 0.7 3.5 0.2 0.8 0.5 0.3 0.1 3.6 3.3 1.7 28.9 1.6 0.4 2.8 2.0 0.4 0.8 5.4 3.0 0.4 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 2.2 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 48.6 0.0 48.4 96.3 234.2 0.3 165.3 0.5 0.2 0.1 0.2 63.8 0.2 0.2 0.1 74.7 3.7 193.0 6.7 0.4 44.8 0.9 1.1 6.2 4.2 1.0 1.3 2.6 1.8 2.4 1.7 2.8 3.2 0.1 0.0 6.4 0.0 1.3 0.1 0.0 0.1 0.0 0.4 0.1 0.4 0.2 1.5 3.3 0.0 2.1 0.1 2.7 0.1 0.0 0.0 0.3 0.0 0.0 0.8 0.0 1.7 2.7 0.0 0.2 0.3 0.0 0.0 22.8 0.0 1.1 0.3 20.6 0.0 2.1 0.1 0.0 33.2 0.7 0.2 0.0 47.0 0.0 3.7 39.9 0.0 1.0 0.5 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702379-1724357 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 85.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" Cytosol "CAB010467: AB_631212, HPA025061: AB_1846407, HPA073626: AB_2686619" "unprognostic (6.25e-2)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (9.32e-3)" "unprognostic (3.54e-2)" "unprognostic (2.25e-3)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.28e-1)" "unprognostic (5.58e-3)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.15e-6)" "unprognostic (1.97e-1)" "unprognostic (5.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" 17.7 17.0 14.9 24.8 15.3 41.7 17.7 18.7 16.2 22.2 14.9 25.0 29.3 19.4 8.8 15.7 20.6 9.4 13.5 14.3 15.8 15.5 18.6 27.4 23.3 15.9 14.6 20.3 17.2 9.3 18.5 12.5 15.4 20.3 14.7 13.1 16.8 7.8 26.0 19.8 36.7 8.8 12.9 36.7 20.3 21.6 15.1 17.0 20.0 7.6 13.8 17.8 19.1 16.4 26.6 16.3 18.7 16.9 20.5 14.5 13.4 25.4 14.3 18.7 20.1 21.9 30.1 31.8 15.2 10.0 19.8 27.1 14.3 15.0 14.3 25.4 19.4 28.8 42.6 20.4 13.3 29.6 45.9 17.1 10.7 13.5 12.2 20.3 22.2 21.4 35.7 27.4 11.1 15.5 19.0 33.4 18.1 18.4 16.0 27.7 19.0 18.9 12.3 13.0 17.7 22.6 25.0 36.3 37.9 7.6 20.4 19.4 22.7 24.3 18.5 10.9 17.2 38.0 31.1 35.3 9.8 33.1 7.2 64.1 16.7 22.0 14.5 9.0 12.1 19.3 12.4 10.7 5.6 19.5 12.0 9.9 85.3 12.0 11.6 33.3 10.9 3.5 14.9 15.3 18.7 16.2 14.3 15.8 15.9 14.6 15.4 12.9 15.1 16.4 27.7 51.3 59.0 5.9 33.9 14.0 16.0 12.5 22.2 33.0 11.3 10.4 1.0 14.3 38.3 14.7 27.1 16.2 54.1 28.8 9.8 19.7 37.6 18.0 24.2 26.4 9.1 29.0 5.3 15.3 22.6 16.6 52.5 21.8 84.6 18.9 18.5 15.6 12.2 40.4 5.0 29.1 12.2 12.2 26.9 16.3 35.4 28.5 10.6 2.8 25.6 16.1 44.3 4.5 8.7 25.9 51.0 21.4 42.7 16.3 62.0 11.7 34.5 42.4 13.1 21.3 19.1 124.0 93.7 15.3 14.6 30.5 48.1 16.5 23.0 14.3 CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 41.1;Macrophages: 20.9;monocytes: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cell line enriched" "Detected in single" 6 "U-937: 4.1" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" 2.1 0.5 0.1 4.8 0.1 21.3 0.5 0.1 0.2 0.4 0.2 0.7 0.3 0.3 0.8 1.0 1.0 1.0 0.8 0.1 0.1 0.8 1.0 5.7 0.9 0.2 0.2 0.2 1.2 0.0 0.3 0.3 0.2 1.1 0.2 0.0 0.8 0.0 0.2 0.3 1.8 1.0 0.1 32.6 0.8 0.1 0.2 0.3 0.4 0.6 0.6 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 30.1 5.6 0.0 23.1 0.1 0.7 1.2 0.0 23.3 0.0 0.7 0.0 122.7 0.0 9.9 0.2 11.3 12.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 3.9 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.1 0.0 0.0 0.0 0.0 41.1 1.6 0.2 0.0 20.9 1.8 1.9 9.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 CORO7 FLJ22021 ENSG00000262246 "Coronin 7" P57737 16 4354542-4425705 "Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 75.3;RPMI-8226: 142.8" "HPA041657, HPA053586" Uncertain NA NA 50000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA041657: AB_10796351, HPA053586: AB_2682201" "unprognostic (4.75e-3)" "prognostic favorable (8.68e-4)" "unprognostic (2.18e-1)" "prognostic favorable (4.25e-4)" "unprognostic (3.80e-2)" "unprognostic (1.05e-1)" "unprognostic (7.54e-4)" "unprognostic (3.32e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-1)" "unprognostic (3.05e-3)" "unprognostic (1.20e-2)" "unprognostic (6.76e-3)" "unprognostic (8.99e-2)" "unprognostic (1.04e-1)" "unprognostic (9.55e-2)" "unprognostic (4.06e-3)" 15.5 15.8 10.8 16.8 16.4 69.5 13.4 12.1 15.5 12.7 5.0 20.4 15.3 13.8 1.8 10.9 16.7 9.0 11.6 12.6 10.9 15.5 8.8 27.5 24.2 16.5 13.5 8.1 10.8 4.5 13.5 9.7 15.5 17.0 4.7 1.4 13.4 5.6 6.5 11.6 31.0 5.5 10.3 56.5 15.3 27.4 15.2 10.9 14.4 1.6 7.9 14.6 11.6 24.1 8.8 12.0 8.0 8.7 1.6 1.1 13.3 5.0 4.4 7.5 6.8 6.8 20.3 18.0 5.0 5.2 5.9 12.2 6.1 9.1 2.5 6.1 29.9 6.1 15.0 6.2 7.0 20.6 48.3 6.3 2.3 4.5 1.9 2.3 13.6 15.0 18.7 75.3 3.8 30.8 15.2 58.1 10.0 6.5 3.1 47.2 24.9 142.8 4.7 13.3 14.9 5.5 6.4 5.7 14.6 3.3 4.8 32.9 16.9 6.5 10.3 16.7 6.7 35.9 20.3 48.7 4.9 29.2 6.6 17.1 16.8 30.8 14.5 23.5 16.4 8.6 13.1 16.8 14.0 3.6 6.5 9.7 17.3 9.1 20.3 7.3 15.5 15.9 10.8 16.4 12.1 15.5 12.6 10.9 16.5 13.5 15.5 10.3 15.2 24.1 10.3 3.2 10.8 0.0 21.2 9.4 6.4 4.8 2.2 13.6 6.4 3.8 2.7 7.2 6.2 5.5 43.8 11.3 41.2 16.6 3.9 12.1 6.6 9.5 4.0 11.9 7.8 2.1 0.0 16.3 12.3 6.3 8.6 8.0 12.0 3.8 21.0 2.4 37.9 28.6 0.0 9.5 28.5 42.8 19.3 5.8 5.0 31.4 17.8 0.0 26.6 7.4 33.0 0.0 0.0 17.3 16.4 3.4 32.1 7.3 16.0 3.0 14.6 19.1 6.6 11.6 5.9 11.5 7.9 4.4 11.9 9.2 34.4 6.0 13.9 8.2 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.1;dendritic cells: 5.2;granulocytes: 2.5;NK-cells: 11.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1472.7" "Lineage enriched" "Detected in many" 62 "granulocytes: 1472.7" "Cell line enriched" "Detected in single" 26 "HMC-1: 5.8" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" 13.2 0.5 0.3 25.1 0.5 9.5 0.4 0.3 1.7 0.7 0.5 0.4 0.2 0.2 0.0 1.6 2.9 4.1 1.8 0.3 0.3 0.5 2.0 9.7 0.3 0.4 0.4 0.1 1.5 0.3 0.2 2.6 1.2 0.3 0.2 0.0 0.5 0.1 0.4 0.3 0.6 1.8 0.3 40.5 0.9 0.2 0.5 1.8 0.4 12.0 0.6 5.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 2.3 2.9 23.7 0.8 0.3 0.2 2.1 6.1 0.7 0.1 0.4 8.7 1472.7 1.5 3.2 0.9 0.3 8.3 0.3 0.5 0.3 1.7 0.3 0.3 0.4 0.4 1.2 0.3 0.5 0.3 0.0 0.0 5.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.7 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 1632.1;Hofbauer cells: 2171.9;Kupffer cells: 1734.2;Macrophages: 1682.8;monocytes: 1688.5;NK-cells: 1805.4;Plasma cells: 1990.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 1058.3;RPMI-8226: 1631.2;THP-1: 1231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009492 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009492: AB_2090309" "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" 149.9 68.0 40.3 344.4 41.8 742.0 93.3 46.0 58.0 81.9 62.4 200.9 196.6 60.8 38.5 80.9 95.4 122.5 93.2 38.6 55.0 187.7 71.5 234.6 333.8 73.8 49.3 40.0 108.6 13.4 40.6 54.9 64.1 75.2 79.9 1.8 116.7 26.6 41.8 39.4 245.3 51.3 65.4 693.1 236.0 10.4 62.4 87.1 136.5 19.9 192.8 144.6 74.1 92.2 2.5 663.0 2.6 1.5 1.3 0.4 329.5 155.7 77.3 39.3 24.1 447.2 819.6 510.5 420.7 56.4 0.0 250.5 21.4 0.9 5.8 146.1 564.1 99.0 217.7 694.9 75.7 156.3 397.6 80.7 0.0 1.6 0.3 1.9 23.9 103.6 278.5 567.5 3.2 1058.3 147.9 822.3 106.2 248.7 1.5 437.9 1.6 1631.2 324.9 490.9 84.2 76.5 482.7 78.8 138.5 60.8 1.4 1231.3 129.8 1.5 6.1 1.8 2.2 362.9 459.9 543.6 195.5 464.9 53.4 120.2 103.8 733.7 76.7 150.1 55.8 109.8 36.7 70.4 107.0 110.7 28.9 36.7 192.3 36.4 143.3 196.3 41.2 47.3 40.3 41.8 46.0 58.0 38.6 55.0 73.8 49.3 64.1 65.4 62.4 92.2 157.8 16.0 12.4 0.0 1290.9 119.4 233.4 420.8 53.5 0.4 131.7 133.2 12.8 368.9 487.1 285.1 2.1 45.3 1632.1 807.2 127.2 636.8 4.2 219.5 137.5 137.1 230.5 162.7 0.2 155.3 299.0 184.8 285.4 312.5 279.0 104.3 317.0 23.9 2171.9 0.0 0.2 540.3 233.9 1734.2 1370.8 14.0 50.1 1682.8 1152.6 32.8 1688.5 1.6 1805.4 1.0 0.2 682.8 1045.8 21.4 1990.6 191.8 390.4 1057.4 529.7 2.7 59.2 44.0 164.3 0.9 15.6 75.2 85.7 118.2 838.6 20.5 805.2 436.9 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 DENND4B KIAA0476 ENSG00000198837 "DENN domain containing 4B" O75064 1 153929501-153946718 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040188, HPA071133" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Golgi apparatus" "HPA040188: AB_10671168, HPA071133: AB_2732173" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (1.59e-2)" "unprognostic (9.42e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-3)" "prognostic unfavorable (4.14e-4)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.18e-5)" "unprognostic (2.21e-1)" "prognostic unfavorable (9.27e-9)" "unprognostic (4.24e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.56e-3)" 18.2 13.4 10.9 24.3 11.1 37.1 15.7 2.3 19.1 17.1 0.0 15.6 9.5 16.3 3.4 10.2 16.2 10.0 21.3 10.2 6.5 13.8 11.4 24.2 30.1 12.0 7.8 19.6 15.5 7.7 13.1 10.3 13.0 13.0 6.0 9.5 11.7 7.0 49.2 11.0 22.0 8.9 3.1 41.0 12.9 7.6 9.8 14.6 15.2 29.5 17.3 15.1 12.9 10.0 12.0 22.7 17.1 17.3 10.0 9.7 17.8 11.5 12.4 17.8 16.6 13.8 13.4 29.9 19.1 7.8 13.5 20.9 15.5 10.6 8.0 27.5 14.0 26.5 26.1 13.3 13.9 28.0 51.5 8.8 18.3 16.6 17.8 14.8 12.8 32.3 28.7 16.4 10.3 24.6 34.2 25.7 23.8 14.1 21.8 36.2 11.5 17.3 8.5 17.6 20.3 24.9 12.1 28.4 16.7 17.0 20.6 68.0 13.5 19.2 18.5 16.1 18.7 49.3 37.7 39.5 13.2 21.7 23.5 1.5 1.6 0.4 1.1 2.4 1.4 1.0 0.9 0.7 1.4 0.9 0.4 1.0 1.5 0.7 1.9 1.9 0.7 1.5 10.9 11.1 2.3 19.1 10.2 6.5 12.0 7.8 13.0 3.1 9.8 10.0 14.7 9.6 10.3 18.6 20.3 4.7 3.7 4.6 1.2 22.3 7.1 6.9 22.9 8.6 5.7 7.3 6.2 4.6 31.9 4.8 5.9 5.2 1.2 4.0 8.0 11.8 4.9 9.5 21.8 6.5 4.7 7.2 13.7 7.4 17.2 12.5 10.8 9.2 18.0 35.3 23.6 4.6 2.0 30.2 11.7 1.9 7.5 31.1 5.4 18.7 22.5 5.8 30.9 19.1 27.9 6.1 4.8 7.9 7.1 6.8 7.6 2.7 4.4 17.8 6.6 7.9 6.0 6.4 8.1 5.7 3.4 3.4 17.0 9.2 7.1 5.2 DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "dendritic cells: 130.6;Hofbauer cells: 131.8;Kupffer cells: 171.8;Langerhans cells: 288.4;Macrophages: 181.5;NK-cells: 344.0;T-cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 25.3;HEL: 54.3;HMC-1: 119.8;JURKAT: 22.3;THP-1: 43.1;U-937: 42.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" 9.5 5.0 1.1 26.5 1.2 19.5 5.0 1.2 2.3 1.9 2.5 5.5 7.0 2.2 0.5 2.3 3.5 6.5 3.5 1.3 1.3 3.0 6.1 25.6 26.3 1.4 1.5 1.4 1.9 0.5 1.1 7.9 1.5 2.3 3.6 0.0 3.4 1.5 2.0 2.3 9.5 6.9 1.2 40.9 6.8 1.6 4.5 16.4 2.4 1.6 7.8 8.4 2.3 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 54.3 0.0 0.1 0.0 0.4 119.8 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.8 5.0 0.0 0.0 0.9 8.7 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.3 1.4 42.0 0.2 577.6 484.3 1565.6 398.3 624.0 184.5 14.5 274.3 304.8 421.9 6.6 151.0 185.9 37.2 307.6 580.7 7.6 597.2 810.3 1.1 1.2 1.2 2.3 1.3 1.3 1.4 1.5 1.5 1.2 4.5 1.5 2.0 3.2 18.1 0.0 13.2 11.5 0.6 0.0 0.0 0.0 1.2 1.8 2.1 0.0 1.3 3.7 0.0 0.7 130.6 0.3 0.0 0.1 0.2 0.2 0.5 2.8 0.0 10.5 0.1 0.0 1.0 2.6 3.1 0.4 36.3 0.1 5.7 1.1 131.8 0.0 0.0 0.2 0.0 171.8 288.4 0.6 0.3 181.5 19.6 0.0 74.8 0.0 344.0 0.0 0.0 0.0 0.0 0.0 15.4 0.2 0.0 0.7 1.5 0.0 0.0 0.6 2.5 0.2 4.3 0.7 8.5 1.0 147.4 0.0 0.2 0.8 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.3;lymphoid tissue: 28.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 29.9;Kupffer cells: 55.0;Macrophages: 34.6;monocytes: 28.6;NK-cells: 25.7;Syncytiotrophoblasts: 54.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 410.0;eosinophil: 841.1;neutrophil: 358.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 841.1" "Cell line enhanced" "Detected in some" "HEL: 4.1;HMC-1: 18.1;NB-4: 4.1;U-937: 6.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 12.3" HPA035644 Approved NA NA 330000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA035644: AB_10670164" "unprognostic (8.81e-2)" "unprognostic (7.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (6.66e-3)" "unprognostic (1.03e-1)" "unprognostic (5.47e-2)" "unprognostic (3.69e-2)" "unprognostic (1.68e-1)" "unprognostic (6.01e-2)" "unprognostic (1.46e-1)" "unprognostic (3.91e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (7.78e-3)" "unprognostic (3.91e-2)" 6.0 0.9 4.3 12.6 4.4 23.3 2.8 4.3 9.3 2.3 4.1 4.1 3.3 1.4 0.6 1.8 2.8 6.2 2.4 4.1 4.8 1.8 3.8 18.5 18.8 6.3 4.9 0.6 1.0 0.9 0.7 13.4 5.1 1.5 4.1 0.2 1.7 1.2 1.4 1.2 11.9 4.0 5.1 28.6 3.2 2.8 5.6 9.0 2.5 3.3 18.3 8.1 1.3 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 4.1 0.0 0.1 0.0 0.1 18.1 0.0 0.1 0.0 0.0 0.1 0.1 1.3 0.3 0.1 0.0 0.0 0.1 4.1 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.5 0.0 0.0 0.0 0.0 1.0 0.5 0.3 0.0 6.3 0.0 410.0 82.6 841.1 17.0 101.9 19.8 30.3 29.5 13.7 33.0 35.9 34.7 17.8 358.8 44.7 126.7 5.3 31.8 48.9 4.3 4.4 4.3 9.3 4.1 4.8 6.3 4.9 5.1 5.1 5.6 6.6 0.9 0.0 7.9 0.0 20.4 2.0 0.0 0.3 1.2 0.0 0.2 0.3 1.8 0.0 1.7 0.0 0.0 10.0 8.7 0.1 0.0 0.1 0.2 0.1 0.1 4.8 0.0 2.1 0.1 0.0 0.7 1.0 0.5 0.1 2.5 0.0 18.9 0.1 29.9 0.0 0.2 0.0 2.0 55.0 21.0 1.1 0.0 34.6 3.6 10.3 28.6 0.0 25.7 0.0 0.1 0.0 0.0 0.4 3.4 0.0 0.0 0.3 8.6 0.0 0.0 0.3 0.8 12.0 9.4 0.1 1.3 54.0 13.1 0.0 0.0 0.1 ERICH1 ENSG00000104714 "Glutamate rich 1" Q86X53 8 614746-738106 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003725 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA003725: AB_1853023" "unprognostic (7.19e-2)" "unprognostic (1.38e-2)" "unprognostic (7.73e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-2)" "unprognostic (1.02e-1)" "unprognostic (7.51e-3)" "unprognostic (1.55e-1)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (8.45e-2)" "unprognostic (5.11e-2)" "unprognostic (1.27e-1)" "unprognostic (8.63e-2)" "unprognostic (3.07e-1)" "unprognostic (1.42e-1)" 15.9 8.7 7.3 17.2 6.5 23.0 13.7 6.4 8.2 10.7 8.3 11.0 8.4 10.1 6.6 10.4 10.5 9.1 10.7 6.9 7.1 22.5 11.6 14.6 21.1 9.0 7.1 11.6 9.0 7.9 11.5 10.1 8.4 9.1 7.2 5.1 9.8 5.8 10.8 13.0 12.4 7.9 6.0 15.3 10.5 8.0 8.4 11.8 13.2 5.5 10.7 12.7 11.6 7.1 15.8 22.2 11.7 14.0 12.4 15.0 24.3 14.9 7.9 13.3 14.6 14.4 9.9 36.0 6.9 12.5 25.3 26.0 21.7 22.9 9.4 15.7 28.1 25.1 15.1 20.8 13.9 15.5 22.6 17.4 14.5 10.1 13.0 13.7 14.7 31.2 26.3 20.2 13.5 13.2 30.0 27.5 18.6 17.6 9.9 27.0 7.6 25.0 14.9 28.7 5.4 15.0 10.9 13.8 20.2 19.2 5.8 18.4 23.7 9.7 4.6 0.6 16.2 13.1 36.7 38.9 19.9 24.6 10.5 24.7 33.0 12.5 8.4 32.3 7.5 17.9 9.7 8.4 17.1 20.1 8.1 7.1 30.0 12.3 29.8 12.7 7.5 10.4 7.3 6.5 6.4 8.2 6.9 7.1 9.0 7.1 8.4 6.0 8.4 7.1 71.0 44.8 36.1 17.9 75.3 36.6 47.0 47.9 32.5 23.3 32.6 32.5 23.0 27.1 31.2 33.1 12.5 62.0 55.4 49.2 109.5 38.4 16.1 35.9 52.2 65.8 19.7 43.9 24.4 36.6 60.4 40.7 66.8 57.4 41.1 48.3 62.4 31.9 41.9 48.8 21.0 50.4 32.6 70.9 68.0 9.2 60.3 69.9 35.6 23.4 126.9 18.2 78.2 11.1 22.5 55.4 54.3 40.6 34.6 51.5 33.3 58.9 26.9 22.1 39.5 33.6 35.6 48.5 58.4 23.2 40.9 54.0 68.3 27.0 39.8 37.0 EVI2B "CD361, D17S376, EVDB" ENSG00000185862 "Ecotropic viral integration site 2B" P34910 17 31303770-31314105 "CD markers, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.0;lymphoid tissue: 169.8" "Cell type enhanced" "Detected in many" "B-cells: 233.2;Kupffer cells: 522.3;Langerhans cells: 169.8;Macrophages: 271.9;monocytes: 426.4;T-cells: 170.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1366.0" "Group enriched" "Detected in all" 5 "granulocytes: 1366.0;monocytes: 381.9" "Cell line enhanced" "Detected in many" "Daudi: 87.9;HL-60: 99.9;HMC-1: 133.3;Karpas-707: 96.4;NB-4: 79.4;RPMI-8226: 147.7;THP-1: 124.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007346, HPA053383" Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA007346: , HPA053383: " "unprognostic (1.07e-2)" "unprognostic (1.20e-2)" "unprognostic (5.97e-2)" "unprognostic (4.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.56e-2)" "unprognostic (3.32e-2)" "unprognostic (8.64e-2)" "unprognostic (2.73e-2)" 24.6 11.0 6.4 100.9 7.3 189.0 13.8 7.3 11.6 13.1 8.7 27.9 23.7 7.4 4.3 11.8 7.8 30.5 6.7 6.3 8.4 5.1 24.9 61.1 159.5 13.3 10.3 5.5 3.0 3.8 1.8 15.4 10.8 7.4 30.5 1.2 11.8 6.1 2.0 5.1 39.2 17.0 7.7 158.8 33.7 3.7 8.5 76.4 5.3 12.2 169.8 38.5 4.1 11.1 0.6 0.7 0.0 0.0 6.5 8.3 0.1 0.8 5.8 6.7 12.4 0.0 3.4 87.9 0.1 5.5 26.4 0.6 0.0 1.2 7.5 0.1 0.0 2.1 0.0 0.0 66.0 99.9 133.3 15.3 0.0 3.9 5.3 2.2 6.9 7.3 1.4 96.4 19.8 0.0 29.4 79.4 0.1 0.0 0.0 51.0 0.4 147.7 0.3 0.2 0.0 0.1 0.4 0.2 0.5 0.0 0.0 124.8 7.2 1.9 0.2 0.7 7.0 18.4 0.9 18.9 8.6 34.0 2.2 1005.3 328.9 798.7 79.2 240.1 76.8 183.6 120.8 102.8 149.9 146.2 91.9 87.5 1366.0 44.2 381.9 86.3 173.6 251.4 6.4 7.3 7.3 11.6 6.3 8.4 13.3 10.3 10.8 7.7 8.5 11.1 2.1 0.0 14.8 0.7 233.2 5.4 0.7 0.7 1.8 0.2 1.5 1.7 1.0 2.8 6.7 1.8 0.0 0.6 129.0 1.3 0.0 0.3 8.3 0.1 0.3 5.6 0.0 6.5 2.7 0.0 0.8 4.0 1.5 0.4 82.2 0.0 7.5 2.3 89.1 0.0 3.1 0.1 2.0 522.3 169.8 9.0 0.0 271.9 37.4 11.2 426.4 0.0 117.4 4.0 31.7 1.0 0.0 0.4 110.4 0.4 0.1 1.1 2.4 0.8 19.7 1.2 1.9 0.4 0.4 0.4 3.7 0.3 170.9 0.0 1.3 1.1 FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 14 "dendritic cells: 43.4;NK-cells: 79.3;T-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" 0.3 0.8 0.1 1.0 0.2 2.8 0.6 0.1 0.2 0.4 0.1 0.8 1.9 0.5 0.7 0.3 0.3 1.1 0.3 0.2 0.1 0.3 1.1 2.0 5.7 0.3 0.2 0.3 0.1 0.0 0.1 0.2 0.2 0.5 0.9 0.0 0.9 0.3 0.1 0.4 1.4 0.3 0.0 4.1 1.5 0.2 0.1 0.6 0.2 0.0 1.8 0.8 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 58.1 0.2 35.5 0.0 11.5 31.4 0.1 0.0 2.2 25.0 1.9 41.5 0.1 0.0 0.2 14.9 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.4 0.4 0.0 2.5 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 43.4 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.6 1.8 0.0 0.9 0.0 79.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 28.8 0.0 0.0 0.1 FCGR3B "CD16, CD16b, FCG3, FCGR3" ENSG00000162747 "Fc fragment of IgG receptor IIIb" O75015 1 161623196-161631963 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.6;lymphoid tissue: 82.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Club cells: 3.1;dendritic cells: 2.2;Fibroblasts: 2.2;Kupffer cells: 2.2;Macrophages: 4.3;NK-cells: 2.1;Respiratory ciliated cells: 2.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.7" "Immune cell enriched" "Detected in many" 79 "neutrophil: 7208.7" "Lineage enriched" "Detected in many" 79 "granulocytes: 7208.7" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (1.60e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-3)" "unprognostic (4.16e-2)" "unprognostic (1.15e-1)" "unprognostic (6.52e-2)" "unprognostic (3.97e-2)" "unprognostic (6.96e-3)" "unprognostic (2.53e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (8.67e-2)" "unprognostic (5.16e-2)" "unprognostic (1.35e-1)" "unprognostic (8.37e-3)" "unprognostic (2.28e-1)" "unprognostic (9.24e-2)" 23.0 2.8 0.6 76.4 1.2 36.6 1.3 0.7 6.7 2.8 1.1 2.1 0.5 0.9 0.0 5.0 5.2 16.4 3.5 0.6 0.7 1.9 7.9 22.0 1.3 1.0 0.8 0.4 4.0 1.4 0.7 9.1 2.7 0.8 0.9 0.0 1.3 0.4 0.8 4.0 2.4 5.6 0.7 82.0 1.8 0.2 1.1 6.1 1.3 23.0 1.5 18.3 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.1 12.5 17.2 30.4 0.6 0.3 0.9 6.9 3.0 0.6 0.5 6.2 7208.7 3.6 90.8 0.4 0.6 18.5 0.6 1.2 0.7 6.7 0.6 0.7 1.0 0.8 2.7 0.7 1.1 1.1 0.0 3.2 7.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 1.5 3.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.3 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 2.2 0.0 0.9 0.0 4.3 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 FCRL6 "FcRH6, FLJ16056, IFGP6" ENSG00000181036 "Fc receptor like 6" Q6DN72 1 159800511-159816257 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;lymphoid tissue: 12.8" "Cell type enhanced" "Detected in some" "dendritic cells: 60.6;NK-cells: 150.4;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 142.9;memory CD8 T-cell: 134.3;naive CD8 T-cell: 102.8;NK-cell: 51.3" "Group enriched" "Detected in many" 26 "NK-cells: 51.3;T-cells: 142.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.64e-3)" "unprognostic (1.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.62e-3)" "unprognostic (1.85e-1)" "unprognostic (1.84e-3)" "unprognostic (5.79e-3)" "unprognostic (6.65e-3)" "unprognostic (2.76e-2)" "unprognostic (3.91e-1)" "unprognostic (1.98e-1)" "unprognostic (1.61e-1)" "unprognostic (1.52e-5)" "unprognostic (3.98e-1)" "unprognostic (1.13e-1)" "unprognostic (8.78e-2)" "unprognostic (9.18e-2)" 0.8 1.5 0.3 1.9 0.4 7.9 1.1 0.7 0.4 0.6 0.3 0.7 1.0 1.3 2.3 0.6 1.0 2.2 0.8 0.4 0.5 0.6 3.3 5.7 5.8 0.9 0.5 1.4 0.3 0.3 0.3 0.5 0.6 0.7 0.5 0.0 2.3 0.4 0.5 0.3 1.4 0.9 0.5 12.8 0.8 0.4 0.6 1.3 0.6 0.1 1.9 1.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.1 142.9 0.3 3.0 0.1 25.5 134.3 3.7 0.1 10.9 102.8 1.5 51.3 1.4 0.2 0.1 53.6 0.3 0.4 0.7 0.4 0.4 0.5 0.9 0.5 0.6 0.5 0.6 0.9 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.0 60.6 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.7 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 1.0 1.1 0.0 150.4 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 FERMT3 "KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2" ENSG00000149781 "Fermitin family member 3" Q86UX7 11 64206678-64223891 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.6;lymphoid tissue: 130.1" "Cell type enhanced" "Detected in many" "dendritic cells: 118.3;granulocytes: 96.4;Hofbauer cells: 193.1;Kupffer cells: 95.8;Langerhans cells: 88.0;Macrophages: 232.9;monocytes: 142.9;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 306.9;HL-60: 135.9;HMC-1: 314.2;Karpas-707: 127.6;MOLT-4: 121.8;NB-4: 174.1;U-937: 138.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065231 Approved Vesicles NA NA 160000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA065231: AB_2685439" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.38e-3)" "prognostic favorable (9.89e-4)" "unprognostic (8.77e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (2.46e-1)" "unprognostic (4.20e-1)" "unprognostic (3.98e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.12e-5)" "unprognostic (3.08e-3)" "unprognostic (5.25e-2)" "unprognostic (4.97e-2)" "unprognostic (1.75e-1)" 25.1 14.5 9.4 63.3 11.6 180.6 13.0 11.2 18.1 8.5 12.2 17.3 22.0 8.4 0.7 6.4 13.6 15.6 12.0 9.8 11.6 11.1 12.5 46.2 89.2 17.9 12.2 5.1 7.0 1.3 5.9 15.0 13.2 8.2 8.1 0.6 10.7 4.4 6.0 7.1 34.1 9.4 13.3 130.1 29.6 4.5 17.1 48.7 10.0 4.6 41.8 19.8 7.3 15.3 1.2 1.6 0.5 0.9 0.3 0.8 2.0 1.4 0.2 0.4 0.3 2.6 2.3 32.6 3.2 6.3 0.7 2.4 1.0 0.5 0.5 83.9 0.6 306.9 1.6 0.1 10.8 135.9 314.2 1.2 1.1 5.2 0.0 0.5 81.2 77.0 7.3 127.6 8.6 3.5 121.8 174.1 1.2 1.0 2.3 72.4 8.8 0.7 0.3 0.7 1.9 0.5 0.7 4.5 1.7 0.7 2.0 92.6 7.8 1.1 2.5 1.9 0.9 1.5 3.3 59.4 19.5 138.9 86.6 204.1 207.0 236.5 120.0 192.6 114.9 54.5 94.1 112.0 162.0 53.1 60.9 80.6 184.6 102.4 151.2 195.7 120.9 292.6 9.4 11.6 11.2 18.1 9.8 11.6 17.9 12.2 13.2 13.3 17.1 15.3 3.8 9.6 14.7 0.7 52.1 4.7 0.9 0.3 3.4 0.5 3.3 5.2 2.4 4.3 3.9 0.0 0.0 1.2 118.3 6.1 0.0 0.8 0.4 4.3 5.6 7.9 0.0 62.5 1.2 2.4 1.4 5.4 19.9 7.3 96.4 0.4 19.6 1.4 193.1 0.0 1.5 32.1 0.0 95.8 88.0 0.9 0.9 232.9 17.8 5.6 142.9 0.3 93.7 1.0 1.5 4.3 10.9 2.6 35.2 0.9 8.2 0.4 1.0 0.3 6.6 13.7 6.6 1.2 0.8 1.9 4.5 2.6 78.5 1.4 15.0 0.7 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 83.4;lymphoid tissue: 110.9" "Cell type enhanced" "Detected in many" "Adipocytes: 46.8;Hofbauer cells: 48.7;Kupffer cells: 92.3;Macrophages: 51.9;monocytes: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 315.8" "Group enriched" "Detected in many" 4 "dendritic cells: 162.6;granulocytes: 315.8;monocytes: 151.7" "Cell line enhanced" "Detected in many" "HEL: 63.5;HL-60: 56.9;HMC-1: 116.6;NB-4: 76.1;THP-1: 110.8;U-937: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 30.8 8.0 9.4 20.2 8.8 83.4 21.3 9.6 10.8 18.1 9.6 12.5 5.8 15.7 2.4 5.9 19.0 14.0 19.6 8.3 8.7 18.9 25.2 30.9 13.8 11.1 9.2 13.5 7.8 2.3 5.6 16.3 10.1 17.9 4.6 1.5 58.3 8.0 6.1 8.0 12.5 10.7 10.4 110.9 9.6 4.5 10.9 4.2 16.0 7.0 5.7 15.1 13.5 9.8 0.4 0.8 0.8 10.3 3.1 8.8 17.9 2.9 0.1 5.1 2.9 2.6 0.1 6.8 0.5 6.0 0.2 1.5 1.7 0.3 1.6 3.3 1.1 63.5 0.0 11.9 6.8 56.9 116.6 8.8 0.1 7.6 0.0 0.0 31.2 9.4 1.8 0.2 0.0 21.3 1.8 76.1 3.2 2.5 0.0 8.6 0.1 0.1 0.0 0.2 0.4 0.1 0.0 2.8 2.3 2.9 0.1 110.8 24.9 0.2 10.4 0.2 0.2 0.1 8.0 2.5 0.3 48.0 2.4 64.4 151.7 315.8 0.5 88.6 0.4 5.2 0.3 0.4 162.6 4.1 0.2 0.3 100.5 51.4 39.8 65.0 0.2 81.5 9.4 8.8 9.6 10.8 8.3 8.7 11.1 9.2 10.1 10.4 10.9 9.8 46.8 3.2 5.8 3.6 5.0 3.8 5.4 0.5 0.6 0.2 4.1 3.8 3.4 8.6 0.5 1.8 0.0 5.3 25.6 0.6 3.9 7.3 1.7 2.0 4.2 29.1 3.0 8.0 2.8 4.3 4.2 9.0 2.0 4.2 29.2 10.7 20.0 15.0 48.7 0.0 0.2 2.0 2.0 92.3 27.9 8.4 9.0 51.9 7.2 5.6 57.8 2.5 26.8 2.0 0.3 2.1 2.0 10.1 4.0 3.1 0.7 1.5 0.2 1.9 13.1 4.6 12.9 4.4 15.9 1.0 2.8 4.5 6.7 3.3 3.7 5.2 FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.3;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 24.1;Intestinal goblet cells: 8.9;Kupffer cells: 11.9;Macrophages: 15.4;Prostatic glandular cells: 7.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.7" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.7" "Cell line enhanced" "Detected in some" "HMC-1: 3.9;OE19: 1.8;SK-BR-3: 1.1;THP-1: 1.2;U-937: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA023985 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" 4.9 0.3 0.2 17.8 0.4 20.3 2.3 0.2 0.4 0.2 0.6 0.8 3.3 0.1 0.0 1.3 1.0 1.4 1.0 0.2 0.2 0.3 1.5 7.5 0.1 0.4 0.4 0.0 0.6 0.3 0.1 1.6 0.5 1.1 0.7 0.1 0.7 0.0 0.2 1.1 4.6 1.3 0.2 22.2 1.2 0.0 0.4 0.7 0.4 3.7 0.7 6.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 3.1 2.1 85.0 0.0 5.6 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 249.7 0.0 6.5 0.1 0.0 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.4 0.4 0.5 0.2 0.4 0.8 5.6 0.0 3.2 0.0 0.6 0.1 0.4 0.3 0.0 0.0 0.2 0.3 0.4 0.0 2.7 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.2 0.0 0.1 0.8 24.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 5.1 0.0 0.4 0.0 5.0 0.0 0.0 8.9 2.0 11.9 2.6 0.1 0.0 15.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 7.7 1.1 0.0 2.2 0.0 0.0 0.4 2.4 0.1 0.2 0.0 0.6 0.1 1.3 0.1 0.6 1.5 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FP565260.1 ENSG00000275464 "Periodic tryptophan protein 2 homolog" 21 5130871-5154658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 9.1;Ductal cells: 9.3;Exocrine glandular cells: 8.0;granulocytes: 5.1;Hofbauer cells: 6.3;Pancreatic endocrine cells: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 102.4" HPA024573 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 1: Pancreatic cells - Digestion" Nucleoli Cytosol "HPA024573: AB_1855963" "unprognostic (3.37e-3)" "unprognostic (4.09e-2)" "unprognostic (4.43e-1)" "unprognostic (9.66e-3)" "unprognostic (2.58e-1)" "unprognostic (1.08e-1)" "unprognostic (1.16e-3)" "unprognostic (1.34e-1)" "unprognostic (2.30e-3)" "unprognostic (8.40e-3)" "unprognostic (5.16e-2)" "unprognostic (1.07e-2)" "unprognostic (9.34e-3)" "unprognostic (1.74e-2)" "unprognostic (5.76e-2)" "unprognostic (5.96e-2)" "unprognostic (1.11e-1)" 9.2 9.2 6.4 9.9 8.8 12.1 7.4 7.2 8.0 5.9 4.9 8.5 9.1 6.8 1.7 8.3 7.8 7.3 7.5 7.1 6.8 9.0 6.8 7.1 13.4 7.6 7.2 6.7 7.7 6.5 6.0 7.9 9.1 6.5 8.4 3.5 6.7 4.7 10.1 8.6 8.2 7.3 6.8 11.5 7.6 7.1 7.2 6.7 6.6 3.2 5.3 11.4 7.1 13.7 32.0 24.0 15.4 24.2 6.6 5.0 9.1 0.2 0.0 0.1 0.1 0.4 20.1 0.3 14.1 10.5 20.8 21.0 42.9 19.0 0.0 7.4 15.1 102.4 12.4 11.9 10.4 47.6 29.1 17.8 22.5 25.5 20.1 5.0 20.1 16.5 56.8 11.6 6.6 28.4 34.4 33.1 60.4 36.5 29.3 54.0 14.2 28.8 13.5 25.3 16.6 27.3 25.5 38.4 14.9 4.2 31.5 24.9 10.2 12.0 29.7 0.3 32.9 13.9 16.0 63.5 20.4 62.3 16.7 3.3 7.3 6.9 18.5 12.6 21.2 11.0 11.3 13.5 8.7 11.2 11.1 15.2 4.1 9.9 18.2 5.5 8.5 11.6 6.4 8.8 7.2 8.0 7.1 6.8 7.6 7.2 9.1 6.8 7.2 13.7 0.9 0.0 9.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 1.9 0.0 0.0 2.5 0.0 0.0 2.7 1.1 0.8 0.0 9.3 0.0 0.8 1.1 0.9 0.0 0.0 0.0 8.0 1.4 0.9 0.0 0.9 5.1 0.6 0.0 0.0 6.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.1 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.3 1.2 0.4 0.9 0.0 FRAT1 ENSG00000165879 "FRAT regulator of WNT signaling pathway 1" Q92837 10 97319271-97321915 "Predicted intracellular proteins" "Wnt signaling pathway" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.2;Early spermatids: 31.3;Kupffer cells: 26.1;Late spermatids: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 8.7;neutrophil: 10.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB046472, HPA055258" Approved Approved Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB046472: AB_1849131, HPA055258: AB_2682763" "unprognostic (1.48e-2)" "prognostic favorable (5.92e-4)" "unprognostic (3.54e-1)" "unprognostic (1.13e-2)" "unprognostic (1.45e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.11e-2)" "unprognostic (4.44e-3)" "unprognostic (5.73e-2)" "unprognostic (2.50e-2)" "unprognostic (6.36e-3)" "unprognostic (1.89e-1)" "prognostic favorable (6.36e-5)" "unprognostic (6.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.31e-2)" "unprognostic (1.43e-2)" 3.2 2.9 2.6 5.0 2.6 10.6 2.4 3.8 3.5 2.5 1.8 3.2 4.4 2.6 1.0 2.4 3.0 1.2 3.1 2.8 3.1 2.1 11.8 3.3 3.8 3.6 3.4 2.4 3.9 2.0 2.1 1.2 3.1 4.0 1.9 1.9 3.7 1.6 3.8 4.2 4.5 1.5 2.9 12.6 4.8 10.9 3.9 4.1 2.0 2.6 2.4 2.3 2.1 2.6 0.7 1.3 1.4 6.7 1.8 0.9 1.5 0.8 2.9 0.5 0.6 0.2 0.8 4.5 1.5 0.5 1.0 2.0 1.1 1.4 0.1 4.0 2.0 3.8 0.8 1.8 0.6 1.4 4.0 0.8 2.0 0.2 0.9 2.7 1.2 6.1 1.6 3.1 0.4 4.2 4.0 7.9 1.9 4.8 5.5 3.3 0.3 2.9 0.5 1.0 0.7 2.2 1.0 2.1 1.5 1.4 7.7 5.4 1.1 0.3 0.4 1.0 0.3 2.9 1.7 1.5 0.5 7.0 0.0 0.9 2.0 8.7 0.5 1.3 0.4 0.5 0.4 0.7 1.0 0.5 0.7 0.5 10.1 0.2 1.5 0.6 0.3 0.5 2.6 2.6 3.8 3.5 2.8 3.1 3.6 3.4 3.1 2.9 3.9 2.6 4.1 3.2 5.8 1.0 5.8 1.1 1.1 0.9 1.2 25.2 2.9 1.9 3.3 5.7 0.9 1.8 0.0 0.6 16.8 6.0 0.0 1.4 31.3 5.8 1.6 4.0 4.2 4.2 0.7 2.0 1.7 1.5 2.0 4.1 0.0 5.0 3.3 15.6 3.9 3.3 1.6 4.9 4.1 26.1 1.8 85.2 1.2 15.5 3.6 0.0 12.5 4.9 13.4 0.5 0.7 1.1 2.3 1.9 1.1 2.5 3.8 1.0 3.3 8.4 0.0 3.4 1.7 1.2 0.6 1.6 1.6 2.3 9.0 4.7 2.8 2.2 FUT7 ENSG00000180549 "Fucosyltransferase 7" Q11130 9 137030174-137032088 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 3.9;brain: 2.5;lymphoid tissue: 6.1" "Group enriched" "Detected in some" 8 "dendritic cells: 66.9;Langerhans cells: 38.7;monocytes: 20.7;NK-cells: 28.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 210.0" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "NB-4: 23.7;THP-1: 24.0;U-937: 14.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA042780 Approved "Golgi apparatus" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus" "HPA042780: AB_2678162" "unprognostic (1.33e-2)" "unprognostic (4.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (5.42e-2)" "unprognostic (5.01e-6)" "unprognostic (2.50e-1)" "unprognostic (2.35e-2)" "unprognostic (6.75e-4)" "unprognostic (4.68e-1)" "unprognostic (1.72e-2)" "unprognostic (3.20e-1)" "unprognostic (6.69e-6)" "unprognostic (3.99e-2)" "unprognostic (4.14e-2)" "unprognostic (1.03e-1)" "unprognostic (8.75e-2)" 0.3 0.1 0.6 1.7 1.7 3.9 0.1 1.0 1.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.1 0.7 1.2 0.1 0.1 0.9 4.6 1.9 1.2 0.0 0.0 0.0 0.2 0.1 1.1 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.4 0.1 0.7 6.1 0.3 0.2 1.2 1.0 0.2 0.4 3.2 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 23.7 0.0 0.2 0.0 1.2 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 2.0 7.5 1.5 10.4 1.6 52.5 20.1 52.1 28.9 21.7 5.5 0.9 4.3 91.6 127.1 0.2 210.0 90.2 15.4 0.6 1.7 1.0 1.3 0.7 1.2 1.9 1.2 1.1 0.7 1.2 2.5 0.1 0.0 0.0 0.0 3.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 66.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 3.7 38.7 0.0 0.0 2.7 0.0 0.0 20.7 0.0 28.8 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 4.6 0.0 0.7 0.0 GAB3 ENSG00000160219 "GRB2 associated binding protein 3" Q8WWW8 X 154675249-154751583 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 20.4;dendritic cells: 32.0;Erythroid cells: 20.4;granulocytes: 20.8;Kupffer cells: 24.7;Microglial cells: 30.9;NK-cells: 39.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 23.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA010090 Approved Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA010090: AB_1849362" "unprognostic (2.67e-2)" "unprognostic (1.04e-2)" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (3.63e-3)" "unprognostic (1.20e-1)" "unprognostic (5.90e-3)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (2.04e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.22e-1)" "unprognostic (2.84e-2)" "unprognostic (5.87e-2)" "unprognostic (2.19e-1)" 3.7 2.1 1.8 7.0 3.5 12.5 2.3 2.6 3.4 1.8 2.2 2.6 3.4 2.0 3.8 1.7 1.9 3.7 7.4 2.0 2.6 1.0 1.9 6.0 7.6 4.7 2.2 1.3 1.0 2.7 0.4 3.7 5.0 1.3 3.4 1.2 2.1 1.9 1.3 3.6 4.2 3.5 2.1 13.9 2.6 4.9 3.6 5.2 3.6 1.6 6.6 3.1 1.1 8.6 0.8 0.0 0.7 1.0 0.9 2.3 0.5 0.3 0.6 0.2 0.3 0.0 0.5 2.5 0.7 0.0 1.5 0.4 0.6 0.4 0.0 2.9 1.0 21.3 2.9 2.4 1.6 6.5 23.3 0.9 0.2 2.0 0.8 0.8 5.2 2.0 4.8 7.3 1.0 0.3 2.4 6.6 0.2 0.0 0.1 3.5 0.0 0.3 1.3 0.0 3.0 0.4 0.3 0.3 0.4 0.5 0.9 3.7 4.8 1.2 1.9 0.8 0.6 8.0 7.0 2.5 2.0 8.4 0.6 26.4 5.9 8.7 13.3 5.7 10.2 1.0 3.5 9.7 5.8 1.3 1.2 6.8 9.0 2.5 3.6 3.3 0.8 5.0 1.8 3.5 2.6 3.4 2.0 2.6 4.7 2.2 5.0 2.1 3.6 8.6 9.9 0.0 6.7 0.7 6.0 0.6 0.0 0.3 0.0 0.1 0.2 0.6 20.4 0.0 1.3 0.0 0.0 0.1 32.0 0.0 0.0 0.8 0.3 0.5 1.2 8.3 0.0 20.4 0.3 0.5 0.6 2.3 0.0 0.1 20.8 2.2 6.1 0.3 13.8 0.0 0.3 0.0 0.0 24.7 5.8 1.7 1.8 18.8 0.0 30.9 16.1 2.6 39.1 8.5 0.3 0.4 0.0 4.5 7.5 0.1 0.0 0.2 1.7 0.4 6.6 0.7 6.6 0.1 1.0 0.2 1.0 0.1 18.6 0.5 0.0 0.1 GMIP ARHGAP46 ENSG00000089639 "GEM interacting protein" Q9P107 19 19629476-19643657 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.9;lymphoid tissue: 54.3" "Cell type enhanced" "Detected in many" "B-cells: 26.6;Gastric mucus-secreting cells: 24.5;Hofbauer cells: 22.7;Kupffer cells: 33.3;Macrophages: 26.7;monocytes: 27.6;T-cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 92.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042484, HPA045481" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042484: AB_2678018, HPA045481: AB_2679343" "unprognostic (7.54e-2)" "unprognostic (5.35e-3)" "unprognostic (3.10e-3)" "unprognostic (4.54e-3)" "unprognostic (1.44e-1)" "unprognostic (1.24e-3)" "unprognostic (1.23e-2)" "unprognostic (4.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (6.85e-2)" "unprognostic (6.75e-3)" "prognostic unfavorable (3.97e-5)" "prognostic favorable (3.03e-4)" "unprognostic (4.92e-2)" "unprognostic (2.54e-1)" "prognostic favorable (5.15e-4)" 7.5 3.3 2.9 32.0 2.4 50.9 5.4 2.5 6.1 3.7 2.5 9.6 10.4 3.3 1.4 8.6 5.4 6.0 2.9 3.8 4.0 4.3 4.7 16.9 29.4 6.5 4.4 2.6 6.0 8.9 3.6 4.6 5.7 5.4 6.5 0.4 6.9 2.8 1.1 6.9 22.6 4.3 4.5 54.3 16.7 2.9 6.6 19.1 8.5 1.9 22.9 8.3 5.3 7.4 9.9 4.5 5.9 6.5 6.4 3.3 23.5 6.1 5.2 3.6 3.4 3.6 13.0 24.1 12.1 4.3 4.7 11.5 3.9 6.7 2.3 8.3 6.1 7.6 7.1 4.0 1.9 21.7 92.0 4.2 4.5 3.9 2.0 4.2 8.2 21.1 5.3 8.5 3.9 14.6 13.7 35.8 3.5 12.7 8.1 23.3 2.6 14.0 6.9 23.3 5.1 15.2 8.4 8.7 3.7 4.5 8.0 30.7 15.0 6.6 3.8 7.6 4.6 4.3 1.9 19.8 4.2 28.0 4.6 7.0 19.5 51.9 13.2 23.7 12.3 12.6 8.4 11.9 15.1 12.8 8.9 9.7 71.8 9.7 33.1 13.5 10.0 12.5 2.9 2.4 2.5 6.1 3.8 4.0 6.5 4.4 5.7 4.5 6.6 7.4 1.7 0.0 10.2 0.3 26.6 1.1 1.7 2.5 1.2 0.0 1.9 1.3 0.9 2.8 3.1 0.0 0.0 0.6 14.9 21.2 0.0 4.1 0.1 1.4 0.9 1.8 0.0 1.3 2.1 4.7 5.3 0.9 24.5 4.0 7.0 3.5 2.5 1.6 22.7 0.0 2.1 6.6 0.0 33.3 6.6 0.4 0.6 26.7 1.8 6.5 27.6 0.4 20.6 0.5 0.2 12.9 20.2 0.7 13.9 2.0 9.3 0.7 1.5 0.1 0.0 0.4 1.6 0.6 1.3 3.5 1.1 0.8 25.8 0.9 6.0 4.1 GP9 "CD42a, GPIX" ENSG00000169704 "Glycoprotein IX platelet" P14770 3 129060779-129062406 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.1;lung: 3.2;lymphoid tissue: 8.9" "Cell type enriched" "Detected in some" 8 "Macrophages: 151.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "basophil: 29.5;neutrophil: 13.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 29.5" "Cell line enriched" "Detected in some" 14 "HEL: 85.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063182 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2600000 "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" Nucleoplasm "HPA063182: AB_2684956" "unprognostic (1.70e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (3.80e-2)" "unprognostic (2.50e-2)" "unprognostic (3.24e-1)" "unprognostic (2.53e-2)" "unprognostic (8.47e-2)" "unprognostic (8.70e-2)" 0.1 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.1 1.8 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 1.2 0.2 0.2 0.7 0.3 0.0 0.0 0.3 0.6 0.1 0.1 0.0 13.9 0.0 0.2 3.0 0.0 51.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.0 14.4 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 2.9 0.1 1.7 0.0 0.0 0.6 0.0 1.3 0.0 18.3 0.0 151.9 0.0 0.0 4.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.7 0.3 0.0 GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049395-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.0;lymphoid tissue: 7.8" "Cell type enhanced" "Detected in some" "B-cells: 23.6;Langerhans cells: 45.5;Macrophages: 30.2;monocytes: 19.1;NK-cells: 15.5;T-cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "HDLM-2: 26.9;Karpas-707: 26.6;THP-1: 8.2" "HPA029694, HPA029695" Supported NA NA "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA029694: AB_10600213, HPA029695: AB_10601984" "unprognostic (2.71e-3)" "prognostic favorable (3.21e-4)" "unprognostic (1.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.16e-1)" "prognostic favorable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (3.35e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (4.18e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (6.71e-2)" "unprognostic (4.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.72e-1)" 2.1 0.7 0.9 7.0 0.7 8.0 0.9 0.7 0.9 0.9 1.0 1.3 1.0 0.6 0.4 0.8 1.6 1.4 0.8 0.8 1.0 5.4 0.5 2.7 7.7 1.6 1.1 0.3 0.7 0.3 0.5 1.5 1.2 0.8 0.9 0.3 0.9 0.3 0.5 2.6 4.3 0.8 1.0 7.8 1.7 0.3 1.2 1.9 4.6 0.6 4.5 2.4 1.1 1.3 0.0 0.1 0.1 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.5 3.5 0.6 0.0 0.0 0.7 0.0 0.0 0.0 26.9 0.3 0.6 0.1 0.0 0.1 2.1 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 26.6 0.0 0.8 0.0 2.7 0.1 0.0 0.0 2.1 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 8.2 0.4 0.1 0.1 0.0 0.3 0.7 2.6 0.3 0.0 2.4 0.0 9.6 6.0 5.5 6.1 7.7 5.9 4.2 4.8 5.5 5.7 4.5 4.8 5.3 4.7 5.8 9.1 3.1 3.6 5.0 0.9 0.7 0.7 0.9 0.8 1.0 1.6 1.1 1.2 1.0 1.2 1.3 0.6 0.0 1.9 0.7 23.6 1.7 0.1 1.0 0.0 0.0 0.3 0.3 0.8 0.0 0.7 1.8 0.0 0.1 12.2 0.0 1.9 0.4 0.0 2.2 0.8 0.9 0.0 4.0 0.7 0.6 0.3 0.4 1.1 5.2 12.7 0.0 0.0 0.0 3.9 0.0 0.6 0.0 0.0 7.1 45.5 0.2 0.0 30.2 5.4 7.5 19.1 0.0 15.5 0.0 0.1 1.2 0.0 0.0 11.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 1.6 0.0 20.7 0.0 0.0 0.9 GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005135-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.6;lymphoid tissue: 9.6" "Cell type enhanced" "Detected in many" "dendritic cells: 256.1;granulocytes: 317.8;Kupffer cells: 112.5;monocytes: 90.9;NK-cells: 319.3;T-cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 5.7;HEL: 6.2;HL-60: 7.5;HMC-1: 9.0;RH-30: 11.5" "Not detected" "Not detected" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (8.56e-2)" "unprognostic (8.65e-3)" "unprognostic (1.98e-3)" "unprognostic (3.59e-3)" "unprognostic (3.10e-1)" "unprognostic (3.55e-3)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (3.79e-1)" "unprognostic (4.46e-3)" "unprognostic (9.03e-2)" "unprognostic (3.80e-1)" 2.0 1.1 0.5 9.1 0.6 12.6 0.9 0.5 0.8 1.1 0.6 1.2 1.6 0.7 0.4 0.9 0.7 2.8 0.6 0.4 1.0 0.8 2.7 4.3 8.8 1.9 1.0 0.3 0.4 0.4 0.4 1.7 1.6 0.8 1.5 0.1 0.7 0.5 0.2 0.3 2.4 2.3 1.0 9.6 1.6 0.6 1.2 4.2 0.4 0.5 6.6 3.4 0.5 2.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.2 0.0 0.0 0.2 7.5 9.0 0.3 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 39.0 19.8 43.6 33.8 28.4 62.4 9.3 16.9 26.2 13.0 8.1 8.6 19.4 15.2 49.1 32.1 5.9 9.0 24.5 0.5 0.6 0.5 0.8 0.4 1.0 1.9 1.0 1.6 1.0 1.2 2.3 2.9 3.2 21.6 0.3 77.8 4.2 0.5 0.0 0.0 0.2 1.9 3.2 0.4 7.2 1.3 0.0 0.0 0.2 256.1 0.5 0.0 0.0 9.1 0.2 0.4 2.1 0.0 6.6 0.0 0.0 0.3 2.3 6.6 0.5 317.8 0.0 3.9 1.4 62.8 0.0 0.0 0.6 0.0 112.5 73.1 1.4 0.6 88.6 3.6 4.7 90.9 0.0 319.3 0.0 0.1 0.0 0.0 0.0 25.6 0.2 0.1 0.3 0.7 0.2 0.0 0.9 2.0 0.1 0.1 0.7 5.3 0.4 192.8 0.9 0.4 0.2 GPSM3 "AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1" ENSG00000213654 "G protein signaling modulator 3" Q9Y4H4 6 32190766-32195523 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 160.8;lymphoid tissue: 229.3" "Cell type enhanced" "Detected in many" "B-cells: 261.0;dendritic cells: 238.9;Hofbauer cells: 278.3;Kupffer cells: 397.2;Langerhans cells: 209.3;Macrophages: 268.2;monocytes: 375.1;NK-cells: 352.2;T-cells: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 226.9;NB-4: 115.8;THP-1: 107.1;U-937: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 73000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.93e-2)" "unprognostic (2.51e-2)" "unprognostic (2.02e-2)" "prognostic favorable (5.98e-4)" "unprognostic (3.55e-1)" "unprognostic (3.07e-2)" "unprognostic (3.66e-1)" "unprognostic (6.61e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (6.92e-9)" "unprognostic (2.01e-2)" "unprognostic (1.69e-2)" "unprognostic (5.47e-2)" "unprognostic (5.87e-2)" 28.7 11.8 11.1 96.8 10.3 160.8 15.5 10.8 14.1 8.9 10.5 17.9 14.4 6.8 9.1 9.4 13.9 24.8 14.9 10.5 13.4 15.9 14.5 62.9 139.9 15.6 13.6 5.3 6.1 1.8 7.6 22.2 13.9 13.8 15.8 0.3 11.8 5.5 3.7 9.1 67.7 10.0 12.3 229.3 17.5 5.6 14.6 83.0 11.6 5.6 100.8 32.8 9.1 14.4 1.0 0.0 1.6 0.6 0.1 0.2 1.5 1.3 17.0 5.6 8.8 0.2 5.2 41.1 7.8 6.7 0.5 0.9 0.1 7.2 3.1 53.8 0.1 59.5 0.0 1.2 9.6 0.0 226.9 2.0 0.0 1.9 5.9 1.2 25.8 25.7 11.4 47.9 1.6 0.0 23.6 115.8 0.0 0.0 0.5 24.5 0.0 38.4 1.4 0.0 0.6 0.1 0.0 0.6 8.7 2.1 1.1 107.1 22.6 3.0 3.1 0.0 1.5 1.1 0.9 25.9 0.9 76.3 15.5 44.1 55.8 194.3 35.5 73.3 35.7 52.8 45.5 44.7 57.9 41.9 38.5 42.7 244.9 27.1 71.5 24.3 34.7 53.2 11.1 10.3 10.8 14.1 10.5 13.4 15.6 13.6 13.9 12.3 14.6 14.4 12.8 0.0 2.2 1.0 261.0 11.2 12.9 11.5 4.0 0.2 7.7 9.1 0.5 2.8 7.3 3.7 0.0 3.4 238.9 2.2 0.0 7.9 6.5 1.1 1.0 19.5 1.2 46.3 0.1 5.2 5.1 7.1 8.6 0.9 57.8 0.5 28.2 4.4 278.3 0.0 0.3 6.5 30.5 397.2 209.3 12.1 1.2 268.2 44.4 4.7 375.1 0.5 352.2 0.0 0.3 20.5 34.2 0.0 76.4 5.8 0.5 2.4 5.5 0.5 6.6 1.3 9.4 0.8 3.9 1.4 8.5 6.3 256.1 7.8 3.7 24.6 GRK2 "ADRBK1, BARK1" ENSG00000173020 "G protein-coupled receptor kinase 2" P25098 11 67266473-67286556 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 197.1" "Cell type enhanced" "Detected in many" "Adipocytes: 33.4;dendritic cells: 80.2;Hofbauer cells: 35.8;Macrophages: 37.6;Pancreatic endocrine cells: 32.4;T-cells: 31.0;Theca cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 318.0;REH: 417.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005021, CAB037248, HPA060707" Enhanced Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB005021: AB_562360, CAB037248: AB_1078280, HPA060707: " "unprognostic (5.58e-2)" "unprognostic (1.75e-1)" "unprognostic (2.01e-2)" "unprognostic (5.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-3)" "unprognostic (3.31e-2)" "unprognostic (6.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (3.66e-1)" "unprognostic (2.40e-1)" "unprognostic (4.04e-2)" "unprognostic (5.19e-3)" 41.2 35.6 42.4 73.0 42.7 197.1 38.0 31.6 63.8 41.3 16.9 54.3 38.2 34.7 10.4 68.1 41.6 28.8 49.1 44.4 32.5 38.6 47.4 64.1 102.4 36.4 31.6 30.1 33.1 16.2 37.5 25.5 36.5 59.1 33.3 7.9 47.1 22.8 55.6 68.3 88.7 25.1 29.1 186.8 45.4 24.1 36.9 74.7 32.2 40.9 77.8 41.3 47.4 41.8 43.1 29.8 28.1 48.0 22.2 19.9 28.7 24.7 23.4 33.0 27.4 67.1 69.0 215.3 39.5 23.0 44.0 56.7 41.3 33.5 17.2 264.4 26.3 122.5 35.4 30.8 27.9 259.5 238.3 18.0 38.2 26.5 34.8 24.4 42.8 87.7 45.3 107.7 29.0 80.7 147.5 318.0 35.3 125.8 44.4 417.0 55.3 65.2 34.0 54.6 57.0 30.8 36.9 52.9 90.5 16.9 49.7 283.0 24.5 26.7 34.8 33.6 28.4 69.2 67.5 195.3 34.0 153.6 24.6 12.6 17.8 19.2 8.4 27.6 6.3 6.1 6.3 7.0 10.2 6.4 5.0 4.9 35.7 6.9 33.7 9.0 4.4 15.9 42.4 42.7 31.6 63.8 44.4 32.5 36.4 31.6 36.5 29.1 36.9 41.8 33.4 3.2 17.9 0.0 16.7 0.0 0.0 0.0 0.0 0.0 24.5 19.7 0.0 0.0 4.3 5.5 0.0 8.9 80.2 0.0 1.9 10.3 0.0 16.6 14.7 9.0 0.0 0.0 0.0 12.6 5.9 6.1 0.0 18.9 21.5 22.3 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.6 0.0 0.0 8.8 0.0 0.0 0.0 0.0 32.4 0.0 0.0 17.7 0.0 0.0 5.6 0.7 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 9.6 31.0 36.3 0.0 0.0 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.9;lymphoid tissue: 25.2" "Group enriched" "Detected in many" 10 "dendritic cells: 575.2;NK-cells: 492.3;T-cells: 302.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 1678.5;memory CD4 T-cell: 490.7;memory CD8 T-cell: 1389.6;naive CD8 T-cell: 1214.0" "Lineage enriched" "Detected in all" 7 "T-cells: 1678.5" "Cell line enhanced" "Detected in single" "U-266/70: 1.0" "Low region specificity" "Detected in many" HPA029200 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favorable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" 3.4 5.2 1.2 3.1 1.3 33.9 4.6 1.3 2.4 2.6 1.6 2.7 2.4 2.0 5.0 3.6 3.5 7.0 2.5 1.1 1.3 1.2 6.7 15.9 25.2 2.0 1.2 2.8 0.8 0.7 2.4 1.6 1.5 1.4 2.5 0.0 7.9 2.1 1.9 0.6 2.8 3.4 1.3 24.4 4.7 0.8 1.4 3.8 1.5 0.6 4.5 7.5 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.2 31.6 3.4 1.7 1678.5 3.6 30.2 7.6 490.7 1389.6 3.3 4.6 155.1 1214.0 18.6 250.8 5.4 44.6 4.5 1436.5 1.2 1.3 1.3 2.4 1.1 1.3 2.0 1.2 1.5 1.3 1.4 1.3 2.9 0.0 4.6 0.0 3.3 1.1 0.1 0.0 0.0 0.0 1.7 1.5 1.4 8.6 0.0 0.0 0.0 0.1 575.2 0.0 0.0 0.1 0.1 0.3 0.3 1.5 0.0 8.6 0.0 0.0 0.0 1.2 1.1 0.4 1.3 0.0 7.5 1.2 0.1 0.0 0.0 0.0 0.0 9.3 3.4 0.2 0.0 4.5 3.6 1.9 3.1 0.0 492.3 0.0 0.1 0.0 0.0 0.0 43.7 0.2 0.0 2.6 0.7 0.0 0.0 1.9 1.3 0.1 0.0 0.4 1.8 0.0 302.2 0.0 0.1 0.1 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 13 "dendritic cells: 385.8;NK-cells: 810.5;T-cells: 243.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.7;HMC-1: 2.1;JURKAT: 3.5;MOLT-4: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 2.2 1.1 0.9 10.0 0.9 21.6 1.1 3.6 2.0 1.4 0.3 1.5 2.1 0.8 0.2 0.8 1.3 1.8 0.8 0.9 0.9 1.0 3.3 5.3 19.2 1.0 0.8 0.7 0.4 0.0 0.9 0.4 1.0 1.3 0.3 0.2 2.8 0.4 0.7 0.8 6.2 0.2 0.7 22.7 3.7 1.8 0.9 8.7 1.6 0.1 3.8 1.5 1.4 1.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.1 0.0 0.4 1.3 0.6 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.1 0.5 0.1 0.3 0.1 9.1 1.4 1.3 583.9 1.7 366.5 0.9 189.2 471.3 1.5 4.0 182.8 379.2 11.9 194.9 2.3 3.6 99.1 227.5 0.9 0.9 3.6 2.0 0.9 0.9 1.0 0.8 1.0 0.7 0.9 1.0 3.4 0.0 0.0 0.3 5.7 3.1 0.1 0.0 0.6 0.5 2.4 2.2 0.1 1.5 0.0 0.0 0.0 0.2 385.8 0.1 0.0 0.4 0.9 0.6 1.5 1.4 0.0 12.0 0.3 0.4 0.4 2.2 13.3 1.1 0.0 0.1 3.6 1.4 0.2 0.0 0.2 0.4 0.0 3.7 4.7 1.6 0.0 5.9 1.8 1.0 8.6 1.6 810.5 0.5 0.3 0.3 0.0 0.0 35.8 0.1 0.0 1.2 0.0 1.4 0.0 1.5 1.2 0.5 1.1 0.9 1.4 0.5 243.6 0.2 0.1 0.1 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HNRNPH1 "hnRNPH, HNRPH1" ENSG00000169045 "Heterogeneous nuclear ribonucleoprotein H1" P31943 5 179614178-179634784 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000914, HPA001359, HPA016884, CAB032820" Supported Enhanced Nucleoplasm NA NA 2800000 "Cluster 49: Eosinophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB032820: AB_2248257, HPA000914: AB_2666143, HPA001359: AB_1079076, HPA016884: AB_1856444" "unprognostic (9.01e-2)" "unprognostic (3.83e-1)" "unprognostic (3.45e-3)" "unprognostic (8.82e-2)" "unprognostic (1.01e-1)" "prognostic favorable (7.85e-4)" "prognostic unfavorable (3.29e-7)" "unprognostic (7.99e-2)" "unprognostic (6.22e-3)" "unprognostic (1.56e-1)" "unprognostic (8.65e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (3.46e-4)" "unprognostic (1.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.40e-3)" "unprognostic (1.72e-3)" 115.8 108.5 83.6 103.2 88.9 242.9 90.4 100.4 99.6 134.4 95.6 109.5 73.3 120.3 67.9 112.7 109.5 71.4 93.0 84.6 88.2 159.3 137.1 102.5 175.0 86.2 86.0 148.4 123.5 99.2 95.5 91.3 86.1 117.5 79.2 162.9 92.5 84.1 142.1 110.5 137.4 102.9 82.8 209.3 105.0 121.2 88.1 210.8 130.8 84.3 166.6 115.6 112.0 88.6 425.0 432.1 496.0 291.0 155.8 135.0 391.5 227.3 188.7 472.0 271.1 519.4 222.0 618.0 205.4 235.2 297.1 227.0 517.8 345.3 552.9 582.8 322.2 335.5 497.3 528.4 196.1 426.0 295.5 104.7 249.1 379.8 230.0 182.6 247.1 293.8 494.4 281.7 279.8 338.5 724.8 371.1 534.9 249.0 226.8 660.7 507.2 368.3 180.4 485.0 431.5 364.3 410.7 232.7 421.8 344.6 275.7 567.1 250.5 415.3 304.2 184.8 556.0 252.0 674.2 723.6 213.0 405.1 501.6 55.7 44.8 46.5 61.4 73.2 82.6 63.4 65.8 66.4 67.9 52.1 81.5 86.8 9.1 62.9 57.6 87.3 83.1 38.9 83.6 88.9 100.4 99.6 84.6 88.2 86.2 86.0 86.1 82.8 88.1 88.6 374.3 115.4 238.0 80.6 263.0 775.3 182.3 89.2 202.1 118.0 332.7 242.1 136.4 165.8 125.5 156.3 131.3 158.3 419.8 183.0 78.2 97.1 151.3 178.7 246.3 237.8 255.2 189.8 81.8 124.1 181.8 241.7 128.0 258.9 247.3 178.6 189.5 225.3 108.2 70.7 85.8 213.7 81.4 186.2 621.4 86.6 111.6 224.0 334.4 104.9 148.3 93.4 110.2 148.8 121.8 105.2 153.0 117.4 269.3 200.4 142.7 75.4 95.9 166.0 184.1 306.3 253.2 189.1 120.6 181.0 718.0 192.5 311.9 87.4 266.4 191.5 HSH2D "ALX, FLJ14886, HSH2" ENSG00000196684 "Hematopoietic SH2 domain containing" Q96JZ2 19 16134028-16158575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.0;lymphoid tissue: 37.7" "Cell type enhanced" "Detected in many" "B-cells: 78.5;dendritic cells: 101.3;Gastric mucus-secreting cells: 40.2;NK-cells: 82.4;Plasma cells: 134.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 232.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 41.0;HL-60: 43.5;HMC-1: 56.4;NB-4: 140.1;RPMI-8226: 63.2;U-266/84: 41.9;U-937: 137.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036616 Approved "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA036616: AB_10671962" "unprognostic (1.69e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (9.46e-6)" "unprognostic (1.06e-1)" "unprognostic (5.50e-3)" "unprognostic (5.21e-3)" "unprognostic (9.35e-2)" "unprognostic (4.78e-2)" "unprognostic (4.21e-3)" "unprognostic (9.96e-2)" "unprognostic (1.57e-2)" "unprognostic (2.22e-2)" "prognostic unfavorable (6.49e-6)" "unprognostic (9.17e-3)" "unprognostic (6.18e-2)" "unprognostic (3.21e-2)" "prognostic favorable (3.47e-5)" 1.6 0.7 0.5 16.8 1.1 47.0 3.3 1.1 1.1 3.0 1.2 9.8 12.7 1.3 1.8 1.7 3.2 5.4 0.4 0.5 0.4 1.5 2.2 5.6 27.2 1.5 0.7 0.5 4.3 2.3 4.0 1.5 1.1 5.1 9.3 0.3 9.5 2.9 0.4 0.4 20.5 1.0 0.7 37.7 12.7 0.4 1.0 8.7 2.6 1.2 35.7 7.5 0.7 2.8 15.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 2.2 21.3 41.0 0.6 0.0 0.8 0.7 0.0 0.6 0.0 2.3 0.1 0.6 0.5 2.6 0.0 43.5 56.4 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 37.4 0.0 9.0 0.1 140.1 0.0 5.5 0.0 3.0 0.0 63.2 0.4 5.6 0.1 0.1 0.0 1.3 0.3 0.0 0.3 15.9 0.2 0.1 0.1 0.2 0.2 5.7 41.9 23.6 0.2 137.3 0.0 232.1 15.5 100.9 17.1 22.0 15.8 56.4 7.6 11.2 25.5 35.8 6.9 9.2 182.6 85.2 38.8 7.6 13.0 16.7 0.5 1.1 1.1 1.1 0.5 0.4 1.5 0.7 1.1 0.7 1.0 2.8 1.0 3.2 8.9 0.0 78.5 0.3 1.2 3.0 0.6 0.0 3.6 1.9 0.6 5.7 11.3 5.5 0.0 2.6 101.3 18.9 0.0 6.7 0.0 4.5 1.5 0.8 8.4 32.2 0.5 5.1 4.1 0.7 40.2 7.9 6.3 0.1 1.4 0.6 1.1 0.0 0.4 19.1 2.0 3.4 2.4 0.1 0.0 7.3 10.6 1.0 10.7 0.0 82.4 1.0 0.3 9.7 18.0 0.0 134.0 2.6 17.9 0.3 7.9 0.0 0.0 1.1 0.7 0.1 0.5 0.1 0.1 3.4 31.0 0.2 9.3 4.1 IFNGR1 "CD119, IFNGR" ENSG00000027697 "Interferon gamma receptor 1" P15260 6 137197485-137219449 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 867.1;Club cells: 405.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025889, HPA029213, HPA063871" Approved Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB025889: , HPA029213: AB_10601023, HPA063871: AB_2685138" "unprognostic (1.73e-1)" "unprognostic (8.86e-2)" "unprognostic (9.85e-3)" "unprognostic (1.71e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-1)" "unprognostic (6.97e-2)" "unprognostic (9.86e-2)" "unprognostic (1.57e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (5.38e-3)" 155.5 59.3 54.6 131.5 57.8 146.2 121.4 64.5 72.1 74.1 56.8 74.7 97.9 58.1 67.4 65.0 55.7 88.4 103.7 53.1 59.9 44.4 104.0 153.8 140.2 71.9 60.3 43.3 44.5 47.4 26.3 86.1 75.9 53.2 74.4 40.4 57.7 57.4 58.3 66.2 101.2 75.9 69.2 165.9 51.3 27.9 59.9 69.2 58.3 75.5 135.2 112.6 58.0 85.0 23.2 23.4 25.1 33.4 166.8 86.7 23.0 67.0 90.0 38.0 53.3 148.7 39.8 24.5 99.2 36.1 55.1 130.0 24.1 62.6 51.5 49.4 37.4 36.1 23.3 192.9 97.3 112.9 46.6 195.9 232.6 33.3 51.4 36.1 48.7 29.1 32.0 34.9 29.2 27.7 17.7 47.0 22.0 191.9 18.6 51.3 28.4 32.1 65.5 104.4 27.4 39.5 77.3 41.9 57.5 47.8 15.5 68.7 71.1 36.2 27.7 48.5 31.8 25.3 25.5 23.8 19.4 69.2 36.5 158.6 518.4 356.3 106.9 502.6 224.7 91.3 60.0 90.0 309.4 98.3 39.2 43.1 736.0 48.4 375.6 85.1 48.0 519.3 54.6 57.8 64.5 72.1 53.1 59.9 71.9 60.3 75.9 69.2 59.9 85.0 298.7 80.1 59.9 21.5 76.4 127.6 177.6 867.1 84.2 15.4 49.8 37.3 49.6 37.1 405.7 27.6 12.5 78.5 240.8 111.0 7.9 74.2 11.6 91.4 52.7 110.7 13.1 25.7 21.4 101.4 67.1 94.7 33.6 112.8 63.3 10.3 62.8 56.5 149.8 10.1 24.2 25.5 270.6 326.2 220.0 6.1 44.1 261.7 49.8 147.1 138.4 23.5 52.5 25.1 44.9 76.0 57.6 49.2 74.5 129.6 82.0 17.2 150.6 28.1 13.1 45.7 75.7 14.6 22.4 47.3 113.2 209.9 121.5 48.3 33.9 140.2 IGHD2-2 IGHD22 ENSG00000211931 "Immunoglobulin heavy diversity 2-2" 14 105916826-105916856 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 14 "bone marrow: 2.9;intestine: 2.5;lymphoid tissue: 2.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 3.0" "Lineage enriched" "Detected in single" 31 "B-cells: 3.0" "Cell line enriched" "Detected in single" 23 "NB-4: 2.3" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "unprognostic (3.23e-3)" "unprognostic (1.40e-1)" 0.0 0.0 0.0 0.9 0.0 2.9 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD3-16 IGHD316 ENSG00000211917 "Immunoglobulin heavy diversity 3-16" 14 105895634-105895670 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "bone marrow: 4.0;intestine: 2.6;lymphoid tissue: 4.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 27.0" "Lineage enriched" "Detected in many" 12 "B-cells: 27.0" "Group enriched" "Detected in some" 16 "HEL: 2.4;HMC-1: 1.3;NB-4: 1.0" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" 0.0 0.0 0.0 1.7 0.0 4.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.8 0.0 0.0 0.0 2.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 27.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Cell type enhanced" "Detected in many" "dendritic cells: 130.1;Extravillous trophoblasts: 85.5;NK-cells: 388.3;T-cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cell line enriched" "Detected in some" 8 "HDLM-2: 525.8" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" 3.2 1.3 2.0 22.4 1.6 36.8 1.9 0.8 2.3 2.2 1.5 5.1 5.5 7.6 2.9 3.5 2.9 6.8 1.9 2.2 1.0 1.0 8.5 12.4 35.7 2.4 2.2 1.6 0.8 0.4 0.6 36.3 1.9 2.3 5.2 0.0 4.3 3.2 0.7 8.9 8.3 2.5 1.7 50.2 6.4 1.5 3.3 14.9 1.8 0.7 24.0 8.0 1.0 1.8 0.4 0.0 1.0 0.0 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 525.8 0.6 1.0 0.0 0.1 0.0 0.0 24.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.7 0.1 4.2 3.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.6 2.3 0.0 0.9 0.0 0.0 13.2 0.0 0.6 36.2 66.0 0.1 0.4 0.4 0.5 5.4 0.1 0.5 50.8 0.6 27.4 0.4 11.4 28.6 0.1 1.9 3.6 15.0 1.2 186.4 0.5 0.3 24.4 37.3 2.0 1.6 0.8 2.3 2.2 1.0 2.4 2.2 1.9 1.7 3.3 1.8 1.5 3.2 6.8 0.0 3.6 3.2 0.7 0.1 5.7 0.0 1.0 0.8 1.7 0.0 0.6 1.8 0.0 0.6 130.1 0.2 0.0 0.3 2.2 0.5 1.2 1.0 0.0 16.8 0.1 0.2 85.5 1.4 5.6 1.2 10.1 0.1 7.1 1.8 2.3 0.0 0.1 0.1 0.0 5.3 1.7 1.6 0.3 3.7 5.4 0.0 2.0 0.0 388.3 0.0 0.1 0.0 0.0 0.0 18.6 0.2 0.1 0.2 0.7 0.0 0.0 0.2 0.9 0.0 0.3 0.5 1.6 1.2 103.6 0.0 0.3 0.1 IRF1 MAR ENSG00000125347 "Interferon regulatory factor 1" P10914 5 132440440-132508719 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 142.1" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 138.1;REH: 114.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011662, HPA063131" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB011662: AB_775784, HPA063131: AB_2684945" "unprognostic (1.30e-3)" "unprognostic (2.00e-2)" "unprognostic (2.47e-3)" "unprognostic (1.21e-1)" "unprognostic (2.27e-1)" "unprognostic (4.48e-2)" "unprognostic (3.67e-1)" "unprognostic (1.64e-1)" "unprognostic (1.52e-2)" "unprognostic (2.24e-2)" "unprognostic (6.93e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.09e-7)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (9.53e-3)" 53.7 19.1 8.2 88.0 7.6 142.1 29.5 8.1 9.4 21.3 7.7 46.3 84.8 21.3 11.7 24.3 24.4 32.6 25.8 7.3 7.5 32.9 54.4 119.0 86.3 17.2 8.1 18.4 15.6 7.4 17.3 22.2 15.8 36.4 38.1 2.8 28.7 16.2 16.7 19.7 68.8 33.1 8.8 117.4 47.4 13.5 10.5 66.4 25.8 13.3 45.3 63.9 24.1 8.0 26.7 22.8 2.3 8.1 22.1 18.9 42.5 14.7 58.8 41.6 52.2 11.3 79.4 26.7 15.8 18.4 64.8 35.7 7.4 33.7 14.3 54.2 7.1 33.2 8.1 6.9 138.1 14.6 34.3 36.9 9.4 31.7 32.2 26.5 22.4 19.1 6.9 97.5 13.1 15.9 87.6 32.7 3.4 9.3 14.6 114.5 23.2 31.7 22.5 27.8 6.4 3.6 14.6 30.8 13.4 10.1 4.7 24.2 13.0 20.5 8.1 12.8 19.8 74.8 27.0 19.3 24.9 27.2 15.5 175.3 167.1 257.0 157.2 244.1 106.9 68.4 104.2 129.9 95.7 62.5 63.5 91.7 621.0 136.9 272.4 52.4 122.1 160.0 8.2 7.6 8.1 9.4 7.3 7.5 17.2 8.1 15.8 8.8 10.5 8.0 369.9 102.5 114.3 1.0 216.5 88.1 129.4 66.3 306.7 14.7 216.5 186.6 17.0 47.1 58.0 22.0 33.3 24.0 396.3 183.6 19.6 112.1 92.5 242.3 170.8 223.1 87.1 36.6 1.1 114.3 42.6 224.4 212.0 288.1 105.2 32.0 58.2 14.6 49.7 1.7 1.2 137.4 57.0 73.9 228.7 9.1 27.4 134.1 72.9 7.5 257.2 16.7 399.6 2.5 1.1 88.6 140.6 7.9 248.6 270.9 155.5 22.4 110.9 46.5 13.1 516.2 225.0 1.3 6.8 118.8 82.7 11.2 301.4 20.5 94.6 95.0 IRF4 "LSIRF, MUM1" ENSG00000137265 "Interferon regulatory factor 4" Q15306 6 391752-411443 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.2;cervix: 19.0;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in some" "B-cells: 57.2;dendritic cells: 66.8;Langerhans cells: 109.7;Melanocytes: 44.4;monocytes: 56.1;Plasma cells: 235.6" "Cancer enriched" "Detected in many" 9 "melanoma: 27.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 10.4;myeloid DC: 10.6;naive B-cell: 10.8;plasmacytoid DC: 12.1;T-reg: 5.8" "Group enriched" "Detected in many" 5 "B-cells: 10.8;dendritic cells: 12.1;T-cells: 5.8" "Cell line enhanced" "Detected in some" "HDLM-2: 221.4;Karpas-707: 197.8;RPMI-8226: 200.0;U-266/70: 177.2;U-266/84: 141.3;WM-115: 109.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA002038, HPA002698, CAB013508" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB013508: , HPA002038: AB_1079148, HPA002698: AB_1851893" "prognostic favorable (6.44e-4)" "unprognostic (1.88e-3)" "unprognostic (1.00e-3)" "unprognostic (1.72e-4)" "unprognostic (2.74e-1)" "prognostic favorable (1.64e-6)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (5.74e-4)" "unprognostic (8.51e-2)" "unprognostic (1.12e-1)" "unprognostic (9.18e-7)" "unprognostic (2.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.90e-1)" "unprognostic (3.65e-2)" 3.1 0.4 0.1 15.9 0.1 29.2 3.2 0.1 0.2 19.0 0.2 6.9 7.6 1.5 0.3 0.9 0.7 2.5 1.0 0.1 0.1 0.4 2.4 2.2 23.2 0.3 0.1 0.6 0.1 0.0 0.3 0.1 0.2 0.5 6.8 0.0 4.5 0.4 0.2 6.8 10.2 0.7 0.2 17.4 7.2 1.1 0.1 7.0 1.1 0.1 26.1 6.3 2.4 0.2 0.4 0.0 0.0 0.0 22.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 221.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.8 0.0 0.0 0.1 0.1 1.2 0.0 0.0 26.1 0.0 200.0 0.0 0.0 0.4 0.0 0.0 0.2 32.0 0.6 0.1 0.3 0.0 0.0 0.1 0.0 0.3 177.2 141.3 58.4 0.2 0.0 109.0 0.1 1.8 0.0 0.6 1.5 0.0 10.4 1.0 1.0 10.6 10.8 1.7 0.7 0.0 0.3 1.5 12.1 5.8 1.5 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.8 0.0 5.3 0.0 57.2 8.3 0.1 0.0 0.0 0.0 0.6 1.5 1.2 1.5 0.0 0.0 0.0 0.0 66.8 0.2 0.0 0.1 0.0 0.3 0.9 0.6 0.0 0.0 0.1 0.7 0.0 1.8 1.5 0.4 0.0 0.0 1.1 0.5 0.3 0.0 0.1 0.1 0.0 0.6 109.7 0.2 3.4 21.7 44.4 0.0 56.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 235.6 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 1.0 0.4 4.3 0.1 29.8 0.0 0.1 0.1 ITGAD "ADB2, CD11d" ENSG00000156886 "Integrin subunit alpha D" Q13349 16 31393335-31426505 "CD markers, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 20.5" "Cell type enhanced" "Detected in some" "dendritic cells: 1.1;Kupffer cells: 4.2;Late spermatids: 1.0;Macrophages: 1.6;T-cells: 2.3" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026786 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026786: AB_10603773" "unprognostic (2.79e-2)" "unprognostic (2.39e-4)" "unprognostic (2.88e-2)" "unprognostic (3.24e-2)" "unprognostic (6.17e-2)" "unprognostic (1.79e-2)" "unprognostic (7.44e-4)" "unprognostic (6.99e-3)" "unprognostic (6.89e-3)" "unprognostic (5.02e-4)" "unprognostic (5.50e-2)" "unprognostic (1.67e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (3.17e-1)" "unprognostic (8.10e-2)" "unprognostic (5.51e-2)" 0.2 0.0 0.0 0.8 0.0 3.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.1 0.4 0.2 0.1 0.0 0.0 1.3 0.3 4.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 20.5 0.1 0.2 0.1 1.2 0.0 0.0 1.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.4 0.4 0.0 0.8 0.0 0.2 0.0 0.0 4.2 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 ITGAX CD11C ENSG00000140678 "Integrin subunit alpha X" P20702 16 31355134-31382999 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 48.1;brain: 33.7;lung: 58.1;lymphoid tissue: 67.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 51.1;granulocytes: 74.0;Hofbauer cells: 45.1;Kupffer cells: 51.5;Langerhans cells: 77.3;Macrophages: 141.7;Microglial cells: 56.2;NK-cells: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 87.5" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 6 "HMC-1: 106.1" "Not detected" "Not detected" "CAB004458, HPA004723, CAB072871" Enhanced NA NA 50000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB004458: AB_626859, CAB072871: AB_2665723, HPA004723: AB_1846231" "unprognostic (9.75e-3)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (1.89e-1)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (9.59e-2)" "unprognostic (8.06e-3)" "unprognostic (3.20e-1)" "unprognostic (7.75e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.82e-1)" "unprognostic (2.95e-2)" 12.9 2.3 6.0 42.7 8.1 48.1 4.3 8.8 33.7 2.2 8.4 2.9 2.3 2.8 0.8 2.0 5.9 10.8 3.5 6.2 9.3 2.9 6.3 58.1 23.2 14.6 11.8 1.0 2.9 1.4 2.9 4.6 14.3 3.2 4.3 0.6 4.5 1.5 1.3 2.1 5.5 4.7 13.0 67.5 4.8 0.6 18.4 4.0 2.8 3.2 12.3 9.2 2.1 24.8 0.1 0.6 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.4 0.0 9.0 0.0 0.3 0.1 0.0 0.3 0.1 18.6 0.1 0.1 0.3 0.4 0.0 1.1 106.1 0.1 0.1 1.7 0.2 0.7 1.0 0.0 0.1 0.4 0.0 0.0 0.1 8.8 0.4 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.1 0.0 3.3 0.8 0.0 1.6 0.0 0.1 0.1 0.0 0.2 4.9 1.8 0.3 12.8 29.1 27.1 4.8 50.3 0.4 2.1 0.1 0.7 34.7 1.0 0.1 0.7 87.5 41.4 61.0 0.6 0.1 11.5 6.0 8.1 8.8 33.7 6.2 9.3 14.6 11.8 14.3 13.0 18.4 24.8 0.8 12.8 51.1 0.0 9.8 2.8 0.3 0.0 0.0 0.1 0.6 1.3 1.5 0.0 10.5 0.0 0.0 0.4 33.6 0.0 0.0 0.3 0.0 0.4 0.5 4.8 0.0 3.4 0.2 0.0 0.6 4.4 0.0 0.5 74.0 0.0 1.1 0.1 45.1 0.0 0.3 0.0 0.0 51.5 77.3 0.0 0.0 141.7 1.8 56.2 35.3 0.1 68.0 0.5 0.3 0.2 0.0 0.0 5.5 0.2 0.0 0.3 1.5 0.1 0.0 0.6 1.0 0.0 0.2 0.0 1.1 0.4 16.5 0.1 0.0 0.1 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 36.4" "Group enriched" "Detected in many" 9 "dendritic cells: 642.3;NK-cells: 1855.8;T-cells: 790.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2177.1" "Group enriched" "Detected in all" 140 "NK-cells: 756.7;T-cells: 2177.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA039113: AB_10674979" "prognostic favorable (3.51e-5)" "unprognostic (1.23e-3)" "unprognostic (7.03e-3)" "prognostic favorable (1.42e-5)" "unprognostic (1.69e-1)" "prognostic favorable (6.99e-5)" "unprognostic (1.54e-3)" "unprognostic (7.15e-3)" "unprognostic (4.12e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.61e-4)" "unprognostic (1.17e-2)" 3.1 1.7 0.7 17.8 0.8 47.4 5.1 0.3 0.8 4.2 0.2 7.7 10.7 1.6 1.4 3.2 1.5 10.7 0.7 0.6 0.7 1.4 11.3 6.7 20.1 0.6 0.6 1.0 0.4 0.2 0.3 1.4 0.6 2.1 8.1 0.1 0.8 1.0 0.7 0.8 20.1 1.6 0.6 28.9 10.1 0.6 0.6 5.7 1.3 0.9 36.4 10.6 1.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.4 0.2 9.5 2.2 1.1 519.7 2.1 2177.1 1.6 307.4 346.1 1.9 1.5 17.1 98.0 10.5 756.7 3.6 3.9 77.9 285.3 0.7 0.8 0.3 0.8 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.8 6.1 0.0 8.9 0.0 19.0 9.7 0.9 0.0 1.2 0.0 5.2 2.5 1.0 4.3 1.3 0.0 0.0 0.4 642.3 1.7 0.0 0.6 0.0 1.9 1.5 6.2 0.0 118.1 0.4 0.0 0.1 7.9 12.2 2.4 0.0 0.0 45.3 10.1 0.9 0.0 0.6 1.0 0.0 36.2 15.8 0.0 0.0 13.2 24.9 0.0 28.1 0.0 1855.8 2.5 0.1 0.0 3.3 0.0 23.0 1.1 0.9 2.0 0.0 0.0 0.0 1.6 4.1 0.0 0.1 1.2 8.8 1.0 790.5 0.0 2.0 1.3 KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.7" "Group enriched" "Detected in some" 8 "dendritic cells: 104.2;NK-cells: 254.3;T-cells: 100.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 229.2;NK-cell: 367.6" "Group enriched" "Detected in many" 46 "NK-cells: 367.6;T-cells: 229.2" "Cell line enhanced" "Detected in some" "HeLa: 5.6;Karpas-707: 1.9" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" 0.7 0.5 0.8 2.2 0.8 5.3 2.0 0.6 1.4 0.7 0.4 1.8 1.4 3.1 1.5 1.4 0.9 2.0 0.7 1.0 1.6 0.3 1.8 3.3 3.1 1.4 1.4 0.7 0.8 0.3 0.3 2.2 1.0 0.7 2.0 1.2 1.2 0.4 0.4 1.0 2.6 0.9 1.2 6.7 4.3 0.9 1.8 1.1 0.7 0.0 2.5 1.0 0.6 2.0 0.2 0.8 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.4 0.8 0.0 0.6 0.1 0.0 0.2 1.6 0.1 0.3 1.4 0.5 0.4 0.2 1.0 5.6 0.0 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 0.4 0.3 0.6 1.9 0.4 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.1 1.7 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 1.0 0.4 0.0 1.9 0.3 0.2 229.2 0.3 29.1 0.6 0.1 40.1 0.3 0.2 0.3 33.2 6.4 367.6 0.6 0.4 0.1 28.6 0.8 0.8 0.6 1.4 1.0 1.6 1.4 1.4 1.0 1.2 1.8 2.0 1.2 0.0 0.6 0.0 1.3 0.1 0.3 0.0 0.0 0.0 0.9 1.3 0.5 1.5 0.0 0.0 0.0 0.1 104.2 0.8 0.0 0.1 1.3 0.3 0.4 0.4 1.8 11.2 0.2 0.0 0.0 0.6 3.1 0.4 0.0 0.0 3.9 0.9 0.1 1.7 0.1 2.8 0.0 4.0 0.4 0.4 0.6 2.0 5.4 0.0 1.4 0.0 254.3 1.0 0.0 0.0 1.2 1.2 17.6 0.1 0.6 0.6 0.0 2.0 0.0 0.1 0.8 1.1 0.6 0.5 0.1 0.1 100.2 0.0 0.5 0.4 KLRD1 CD94 ENSG00000134539 "Killer cell lectin like receptor D1" Q13241 12 10226058-10329608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "dendritic cells: 740.2;NK-cells: 1316.2;T-cells: 324.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 512.6;memory CD8 T-cell: 217.7;naive CD8 T-cell: 218.7;NK-cell: 737.5" "Group enriched" "Detected in many" 68 "NK-cells: 737.5;T-cells: 512.6" "Low cell line specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA069688 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "HPA069688: AB_2686170" "unprognostic (3.75e-2)" "unprognostic (2.15e-3)" "unprognostic (4.95e-2)" "unprognostic (2.48e-3)" "unprognostic (2.13e-2)" "unprognostic (2.60e-3)" "unprognostic (2.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.94e-3)" "unprognostic (4.53e-3)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.47e-3)" "unprognostic (1.78e-1)" "unprognostic (3.07e-1)" "unprognostic (3.06e-1)" "unprognostic (1.37e-2)" 1.6 1.4 1.5 2.8 1.1 8.4 1.8 2.1 2.1 1.2 0.0 1.6 1.8 1.2 1.5 1.3 1.1 1.6 1.1 1.6 0.7 0.8 4.1 4.7 6.8 0.4 0.2 1.1 2.2 0.5 4.6 1.3 0.4 0.6 0.9 1.3 1.3 0.6 1.2 0.9 3.4 0.7 0.1 17.0 2.1 1.2 1.0 0.5 1.2 0.2 4.0 2.1 0.8 3.0 0.2 0.1 0.2 0.4 0.4 0.2 0.2 0.7 0.0 0.0 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.3 0.0 0.2 0.0 0.5 0.5 0.4 0.7 0.1 0.5 0.3 0.2 0.1 0.5 0.1 0.3 0.3 0.1 0.3 0.3 1.2 0.0 0.5 0.3 0.3 0.3 0.2 0.4 0.1 0.4 0.3 0.2 0.3 0.6 0.2 0.2 0.6 0.1 0.9 0.2 0.6 0.3 0.5 0.9 0.4 0.1 0.5 0.5 0.3 0.7 0.2 0.4 1.7 0.8 1.1 512.6 2.0 58.1 0.8 3.5 217.7 1.6 0.8 1.3 218.7 9.2 737.5 1.5 2.1 1.3 163.0 1.5 1.1 2.1 2.1 1.6 0.7 0.4 0.2 0.4 0.1 1.0 3.0 7.4 0.0 10.5 1.3 5.8 0.5 1.2 0.2 0.6 0.7 1.7 1.0 2.7 7.2 1.9 0.0 6.2 1.8 740.2 0.4 0.0 0.6 9.0 1.1 1.2 7.7 0.0 24.0 3.1 0.0 1.0 4.5 10.7 1.8 2.5 0.4 15.0 4.3 0.7 1.7 2.0 0.2 0.0 18.3 1.2 12.6 0.3 7.0 5.4 4.7 5.1 0.3 1316.2 1.5 1.8 0.0 0.0 0.7 91.0 1.3 0.2 1.1 1.5 1.0 0.0 2.2 1.7 1.9 3.5 0.3 0.6 0.8 324.9 0.0 0.3 1.4 KLRF1 "CLEC5C, NKp80" ENSG00000150045 "Killer cell lectin like receptor F1" Q9NZS2 12 9827481-9845007 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.8;lymphoid tissue: 18.0" "Group enriched" "Detected in many" 7 "dendritic cells: 302.0;NK-cells: 963.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 7 "NK-cell: 664.4" "Lineage enriched" "Detected in all" 7 "NK-cells: 664.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.5;HAP1: 1.5;U-937: 4.4" HPA054038 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA054038: " "unprognostic (2.96e-1)" "unprognostic (8.59e-2)" "unprognostic (3.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-4)" "unprognostic (6.06e-2)" "unprognostic (3.68e-2)" "unprognostic (9.95e-3)" "unprognostic (3.00e-1)" "unprognostic (2.90e-1)" "unprognostic (4.43e-2)" "unprognostic (6.53e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.89e-3)" 1.5 0.1 0.6 1.4 0.6 12.8 0.8 0.6 1.4 0.7 0.6 0.7 0.3 0.9 3.8 0.6 1.5 1.4 0.6 0.6 0.6 1.2 4.5 4.4 3.4 0.8 0.6 0.1 1.3 0.3 0.5 1.0 0.6 0.5 1.0 0.1 1.4 1.1 1.2 0.5 0.8 0.8 0.6 18.0 1.2 0.6 0.6 0.4 0.8 0.4 3.5 0.9 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.4 0.6 0.4 0.8 0.9 71.5 1.5 94.4 3.4 3.6 35.2 1.5 1.5 1.4 35.4 5.8 664.4 1.1 2.3 1.2 83.0 0.6 0.6 0.6 1.4 0.6 0.6 0.8 0.6 0.6 0.6 0.6 0.6 3.2 0.0 2.2 0.0 2.3 1.5 1.1 0.2 0.6 0.0 1.3 0.1 0.3 5.7 1.3 0.0 0.0 0.9 302.0 0.1 9.8 0.5 0.5 0.5 0.5 2.2 0.0 24.0 0.1 0.2 0.7 1.2 0.0 1.0 1.3 0.1 8.9 1.8 1.4 0.0 0.2 0.1 0.0 9.1 6.6 1.1 0.0 2.1 12.4 2.8 3.9 0.4 963.0 0.0 0.3 0.4 0.0 0.0 12.7 0.9 0.0 0.8 0.2 0.0 0.0 0.1 0.2 0.2 2.0 0.2 1.1 0.5 80.6 0.0 0.3 3.1 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 LAIR2 CD306 ENSG00000167618 "Leukocyte associated immunoglobulin like receptor 2" Q6ISS4 19 54497879-54510687 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.6;pituitary gland: 2.6" "Cell type enriched" "Detected in some" 7 "Extravillous trophoblasts: 696.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "gdT-cell: 14.0;memory CD4 T-cell: 13.8;memory CD8 T-cell: 19.5;naive CD8 T-cell: 13.2;T-reg: 49.5" "Lineage enriched" "Detected in many" 40 "T-cells: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Hep G2: 1.0" "Low region specificity" "Detected in some" "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.99e-3)" "unprognostic (7.49e-2)" "unprognostic (4.19e-2)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (4.86e-4)" "unprognostic (1.06e-2)" "unprognostic (8.37e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" "unprognostic (3.68e-9)" "unprognostic (1.21e-2)" "unprognostic (3.15e-3)" "unprognostic (3.40e-5)" "unprognostic (6.71e-2)" 0.2 0.0 0.1 0.4 0.3 0.8 0.1 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.1 0.7 1.6 0.2 0.2 0.0 0.1 0.0 2.6 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.1 0.3 0.3 0.4 0.6 0.1 0.2 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 14.0 0.1 0.4 0.0 13.8 19.5 0.1 0.1 2.4 13.2 0.2 1.2 0.3 0.1 49.5 7.8 0.1 0.3 0.1 0.7 0.3 0.3 0.2 0.2 0.4 0.1 0.4 0.5 0.8 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 10.7 95.4 0.9 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.2 696.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.8 1.8 0.0 0.5 0.0 46.4 0.0 0.1 0.6 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 32.2 23.2 0.0 0.0 0.0 LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.6;granulocytes: 171.6;Hofbauer cells: 82.7;Kupffer cells: 71.1;Langerhans cells: 81.9;Macrophages: 89.1;monocytes: 89.6;NK-cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 192.2;REH: 205.7;RPMI-8226: 73.3;THP-1: 186.5;U-937: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" 6.8 5.4 9.7 37.7 11.1 61.3 3.8 11.8 12.8 3.7 9.1 6.5 6.3 2.9 2.5 3.6 4.2 9.1 2.3 10.3 12.2 3.3 4.8 19.2 51.6 18.4 13.6 1.7 3.0 2.2 3.0 7.4 17.7 7.1 7.7 1.2 4.5 3.5 3.3 3.0 13.6 8.8 16.5 47.0 6.5 2.0 15.3 12.2 2.8 2.4 56.6 10.1 2.5 20.1 1.7 1.1 1.1 3.1 0.3 0.0 1.1 1.4 1.2 0.6 0.7 2.3 28.9 19.6 0.4 0.5 6.1 1.2 0.4 1.1 0.6 31.4 1.2 8.6 1.8 1.8 0.1 56.1 55.6 0.4 0.8 2.1 0.6 1.2 0.3 1.1 1.6 9.3 0.5 1.7 1.3 192.2 0.9 5.5 2.0 205.7 1.1 73.3 0.2 1.7 0.9 0.8 0.6 1.2 1.2 0.9 1.1 186.5 2.1 2.1 19.9 0.8 1.8 0.9 6.2 32.2 9.4 177.6 1.5 871.6 276.6 46.0 8.8 159.0 0.9 169.3 2.3 1.4 225.2 191.1 1.0 2.9 491.0 73.9 93.9 8.9 4.9 214.7 9.7 11.1 11.8 12.8 10.3 12.2 18.4 13.6 17.7 16.5 15.3 20.1 1.3 3.2 16.2 0.7 90.6 3.4 0.7 0.0 0.6 0.3 1.0 1.9 1.1 5.7 3.1 3.7 0.0 0.6 47.8 0.2 0.0 0.3 2.4 1.3 0.6 3.9 7.8 16.6 1.7 0.2 1.1 1.7 1.1 2.1 171.6 0.4 3.9 4.5 82.7 0.0 1.4 0.8 0.0 71.1 81.9 3.4 0.0 89.1 1.8 20.6 89.6 0.2 70.0 0.5 0.9 0.6 0.1 0.7 18.7 1.2 0.1 0.2 5.9 1.3 0.0 1.9 0.9 0.4 1.4 0.1 2.6 1.2 27.7 0.3 0.8 0.4 LILRA1 "CD85i, LIR-6, LIR6" ENSG00000104974 "Leukocyte immunoglobulin like receptor A1" O75019 19 54593582-54602381 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 11.9" "Group enriched" "Detected in some" 8 "Kupffer cells: 42.3;Macrophages: 38.7;monocytes: 39.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 126.8;non-classical monocyte: 169.2" "Lineage enriched" "Detected in many" 5 "monocytes: 169.2" "Group enriched" "Detected in some" 8 "THP-1: 1.0;U-937: 1.5" NA NA 94000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (4.52e-2)" "unprognostic (1.12e-1)" "unprognostic (6.30e-2)" "unprognostic (1.59e-1)" "unprognostic (2.34e-1)" "unprognostic (9.46e-3)" "unprognostic (1.17e-1)" "unprognostic (4.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.90e-2)" "unprognostic (8.72e-2)" "unprognostic (1.13e-1)" "unprognostic (8.28e-3)" "unprognostic (8.82e-2)" "unprognostic (3.79e-4)" "unprognostic (2.53e-1)" "unprognostic (9.83e-2)" 0.7 0.5 0.3 8.2 0.3 2.6 0.2 0.4 0.3 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.3 0.8 0.3 0.2 0.4 0.3 0.9 1.8 1.1 0.9 0.6 0.1 0.2 0.1 0.2 0.4 0.7 0.3 0.6 0.0 0.2 0.2 0.1 0.0 0.5 0.7 0.8 11.9 0.2 0.0 0.7 0.3 0.2 0.6 1.1 2.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 47.0 36.0 0.0 126.8 0.0 0.0 0.0 0.1 32.6 0.1 0.1 0.1 35.8 0.4 169.2 4.2 0.1 22.7 0.3 0.3 0.4 0.3 0.2 0.4 0.9 0.6 0.7 0.8 0.7 1.1 0.1 0.0 1.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 4.9 0.0 0.0 0.0 0.0 42.3 0.7 0.0 0.0 38.7 0.0 2.8 39.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.5;lymphoid tissue: 76.3" "Group enriched" "Detected in some" 5 "Kupffer cells: 64.1;Macrophages: 136.1;monocytes: 53.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.7;neutrophil: 137.2;non-classical monocyte: 311.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.2;monocytes: 311.7" "Cell line enriched" "Detected in single" 31 "RPMI-8226: 4.1" "Secreted to blood" NA NA 670000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (8.52e-2)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (6.56e-2)" "unprognostic (2.90e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (6.61e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (3.61e-2)" "unprognostic (6.51e-3)" "unprognostic (4.68e-2)" "unprognostic (6.21e-2)" 7.9 1.3 0.2 36.9 0.2 43.5 1.9 0.2 0.9 0.7 0.6 1.8 0.0 1.0 0.0 0.9 4.1 1.7 2.5 0.3 0.2 1.8 3.8 22.2 0.5 0.6 0.3 0.6 0.9 0.0 0.9 1.6 0.5 1.4 1.2 0.0 1.2 0.0 0.7 0.3 2.8 6.9 0.3 76.3 2.1 0.3 0.4 0.4 1.0 0.0 0.4 15.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 128.6 0.5 0.0 252.7 0.3 0.0 0.0 0.0 39.2 0.1 0.0 0.0 137.2 0.3 311.7 20.3 0.1 65.0 0.2 0.2 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.3 0.4 0.4 0.1 0.0 8.5 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 3.1 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 1.0 0.0 0.0 11.4 0.0 0.4 0.7 6.5 0.0 0.1 0.0 0.0 64.1 14.3 0.0 0.0 136.1 0.0 0.0 53.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.4 2.2 0.0 0.0 0.8 0.2 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 LILRB2 "CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10" ENSG00000131042 "Leukocyte immunoglobulin like receptor B2" Q8N423 19 54273812-54281184 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 35.0;lung: 15.0;lymphoid tissue: 51.2" "Cell type enhanced" "Detected in some" "Kupffer cells: 150.7;Langerhans cells: 61.8;Macrophages: 147.3;monocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "classical monocyte: 61.6;intermediate monocyte: 132.3;neutrophil: 62.9;non-classical monocyte: 153.4" "Group enriched" "Detected in many" 6 "granulocytes: 62.9;monocytes: 153.4" "Not detected" "Not detected" NA NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.23e-1)" "unprognostic (1.12e-2)" "unprognostic (3.21e-2)" "unprognostic (3.51e-2)" "unprognostic (6.21e-3)" "unprognostic (1.70e-2)" "unprognostic (1.44e-2)" "unprognostic (2.94e-1)" "unprognostic (1.08e-2)" "unprognostic (2.98e-2)" "unprognostic (2.64e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.45e-7)" "unprognostic (1.90e-2)" "unprognostic (4.68e-3)" "unprognostic (3.72e-1)" "unprognostic (9.73e-2)" 6.5 2.6 0.0 12.2 0.0 35.0 2.2 0.0 0.5 1.1 0.6 2.3 3.2 1.2 0.1 1.0 3.7 0.0 2.5 0.1 0.1 2.2 3.9 15.0 0.8 0.9 0.5 0.8 1.3 0.0 1.3 0.5 0.6 1.7 0.8 0.0 1.6 0.4 0.6 0.6 3.0 0.4 0.0 51.2 1.8 0.3 1.0 0.2 1.1 0.1 0.0 2.3 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.0 61.6 16.2 0.1 132.3 0.3 0.0 0.0 0.0 18.8 0.1 0.1 0.0 62.9 0.0 153.4 8.0 0.3 29.7 0.0 0.0 0.0 0.5 0.1 0.1 0.9 0.5 0.6 0.0 1.0 0.2 0.5 3.2 10.9 0.0 5.5 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 1.5 3.1 0.0 0.0 0.1 10.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.8 0.0 0.0 0.3 1.0 1.1 0.0 5.1 0.0 2.2 1.5 27.2 0.0 0.0 0.0 0.0 150.7 61.8 0.1 0.0 147.3 3.6 1.0 75.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.3 2.2 0.0 6.6 0.4 0.2 0.0 0.0 0.0 0.6 0.1 2.9 0.0 0.0 0.1 LPAR2 "EDG-4, EDG4, LPA2" ENSG00000064547 "Lysophosphatidic acid receptor 2" Q9HBW0 19 19623655-19628930 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 73.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA019616 Approved NA NA "Cluster 13: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA019616: AB_1847988" "unprognostic (1.60e-2)" "unprognostic (1.83e-3)" "unprognostic (6.39e-2)" "unprognostic (1.19e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-3)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (2.32e-1)" "unprognostic (1.05e-3)" "unprognostic (8.07e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (1.61e-7)" "prognostic favorable (1.43e-4)" "unprognostic (2.40e-1)" "unprognostic (5.87e-2)" "unprognostic (2.29e-2)" 10.3 3.3 6.6 18.7 6.5 51.9 8.2 5.5 9.2 9.4 7.9 12.9 9.6 4.3 2.5 15.9 10.6 13.0 3.7 7.1 8.5 11.0 6.5 28.5 17.1 8.2 8.0 10.4 27.6 7.8 10.0 4.2 8.1 17.8 7.8 1.7 17.2 4.3 1.4 18.2 23.7 1.9 6.8 76.0 33.6 49.5 9.4 10.0 18.4 1.5 14.7 10.8 11.3 8.5 31.4 3.4 35.7 8.0 9.1 4.4 30.2 2.0 2.9 1.4 2.6 22.0 29.6 19.8 19.5 2.9 1.8 32.1 5.6 11.0 1.4 8.5 9.2 4.4 6.9 1.7 1.2 7.4 73.3 4.9 26.9 1.4 2.0 5.0 0.8 9.7 4.4 7.7 1.2 51.4 4.5 12.3 35.3 42.0 14.2 19.6 2.9 9.1 22.1 45.5 12.6 23.0 8.2 6.6 4.9 19.6 16.9 47.0 9.1 6.8 5.7 12.0 3.0 3.4 10.7 6.8 1.5 53.3 3.4 0.2 1.0 3.8 9.2 1.1 16.2 5.5 20.7 11.8 0.7 2.7 18.2 13.5 10.1 2.8 1.7 1.8 25.7 6.3 6.6 6.5 5.5 9.2 7.1 8.5 8.2 8.0 8.1 6.8 9.4 8.5 0.9 3.2 7.2 0.7 7.1 6.2 11.7 12.4 9.1 0.3 9.7 10.8 2.2 5.7 9.9 7.3 2.1 1.0 6.6 12.2 3.9 14.3 0.4 10.2 2.4 1.0 2.4 3.2 1.9 20.1 6.0 1.9 39.3 18.3 3.8 6.9 1.1 0.6 2.5 1.7 2.2 11.5 6.1 5.6 4.0 2.1 0.6 8.3 0.0 5.6 6.4 4.7 2.1 1.0 0.1 16.9 7.1 0.4 8.7 14.9 10.1 0.7 6.0 1.4 0.0 0.4 2.1 1.3 4.2 7.2 5.1 0.1 20.4 0.2 7.6 11.2 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LSM8 YJR022W ENSG00000128534 "LSM8 homolog, U6 small nuclear RNA associated" O95777 7 118184144-118204035 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020116 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Vesicles" "HPA020116: AB_1853385" "unprognostic (1.02e-2)" "unprognostic (6.58e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.85e-4)" "unprognostic (3.33e-2)" "unprognostic (7.34e-2)" "unprognostic (1.13e-3)" "unprognostic (1.87e-2)" "unprognostic (1.79e-2)" "unprognostic (9.90e-2)" "unprognostic (5.14e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.46e-6)" "unprognostic (4.82e-2)" "unprognostic (1.42e-1)" "unprognostic (7.80e-2)" "unprognostic (3.00e-3)" 26.8 19.1 6.2 22.3 8.3 44.8 25.6 16.5 7.7 20.5 6.2 22.0 15.5 19.9 16.5 24.4 18.7 9.2 19.2 6.3 7.5 23.7 18.5 21.2 28.9 7.5 7.4 19.8 24.9 8.4 16.3 10.1 7.7 20.8 14.2 16.7 22.7 7.8 21.7 21.6 26.0 8.3 6.8 30.9 21.3 17.3 7.2 18.2 22.1 7.8 27.5 20.0 20.6 10.5 37.2 21.2 53.7 43.6 11.3 19.4 25.3 36.1 26.4 19.2 21.5 16.8 35.6 70.0 78.9 13.4 51.5 28.2 23.1 16.3 18.6 35.9 27.7 49.5 63.3 48.6 29.2 63.9 59.1 20.8 19.6 24.6 25.8 17.7 19.6 55.8 45.8 71.2 26.1 13.2 142.9 155.6 43.6 28.9 26.0 40.8 32.0 53.3 20.3 27.8 28.2 41.6 29.2 83.0 89.1 36.9 17.3 72.7 17.4 36.9 27.7 56.3 51.2 69.9 52.0 101.1 29.1 66.9 61.5 65.3 46.5 45.5 61.8 66.7 59.8 68.0 67.8 75.6 51.5 58.0 64.6 67.5 15.4 43.9 65.7 93.2 74.2 39.5 6.2 8.3 16.5 7.7 6.3 7.5 7.5 7.4 7.7 6.8 7.2 10.5 108.5 25.6 58.6 15.0 130.3 0.0 93.6 0.0 82.6 41.5 71.8 92.1 43.5 74.4 35.3 62.5 47.9 133.2 141.2 76.8 90.1 101.2 54.6 76.1 92.8 79.6 86.4 83.1 19.5 172.0 193.6 69.0 66.3 76.4 101.4 87.1 88.5 75.3 139.8 42.1 22.4 99.1 0.0 148.9 0.0 19.1 97.3 102.2 0.0 36.5 184.9 52.6 158.6 23.6 39.1 144.8 109.0 76.0 95.6 108.6 83.6 106.8 36.5 42.0 85.5 65.3 66.2 135.3 117.8 106.7 0.0 120.8 121.1 76.1 100.7 121.2 LSP1 WP34 ENSG00000130592 "Lymphocyte specific protein 1" P33241 11 1850904-1892267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 224.7;lymphoid tissue: 245.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 492.2;Langerhans cells: 553.6;monocytes: 1505.6;NK-cells: 352.2;Plasma cells: 338.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 278.5;HDLM-2: 978.9;Karpas-707: 215.4;RPMI-8226: 500.2;U-937: 173.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017781, HPA019693" Enhanced NA NA 1600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB017781: , HPA019693: AB_1853387" "unprognostic (7.53e-3)" "prognostic favorable (3.56e-4)" "unprognostic (4.35e-2)" "prognostic favorable (2.54e-4)" "prognostic unfavorable (5.35e-4)" "unprognostic (1.43e-3)" "unprognostic (3.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.72e-1)" "unprognostic (1.03e-3)" "unprognostic (3.29e-1)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.20e-2)" 75.6 224.7 2.1 148.8 2.6 167.3 51.2 2.4 6.4 63.8 5.3 39.2 33.6 36.8 3.8 42.5 41.7 32.6 48.2 3.8 3.4 6.4 12.1 49.8 154.8 6.0 2.6 5.3 10.7 3.8 7.4 21.8 4.5 13.4 22.3 1.0 52.8 8.1 28.4 98.0 76.6 12.5 4.3 245.0 52.1 8.1 6.0 65.5 24.7 29.4 85.0 83.7 51.4 11.6 0.3 1.2 0.0 0.0 41.0 125.2 0.4 0.0 0.0 0.0 0.0 0.1 0.2 278.5 1.5 0.2 0.3 0.4 0.0 0.0 0.0 978.9 0.0 0.5 0.2 0.4 7.9 1.0 0.9 32.0 0.5 0.1 1.3 0.4 0.1 2.2 0.9 215.4 24.7 0.1 19.6 28.2 0.5 0.0 0.0 1.1 13.6 500.2 0.0 0.0 0.4 3.3 0.2 0.0 0.3 0.0 0.3 0.9 0.5 0.7 4.6 0.3 0.8 1.0 0.7 38.4 0.4 173.0 0.3 365.1 803.6 785.5 384.3 863.3 222.6 452.1 249.1 346.8 896.6 298.8 161.3 260.8 1574.3 279.6 888.2 669.7 491.4 1293.0 2.1 2.6 2.4 6.4 3.8 3.4 6.0 2.6 4.5 4.3 6.0 11.6 18.3 16.0 7.9 0.0 312.8 118.3 14.0 43.0 76.8 0.8 3.9 4.3 2.7 8.6 37.6 3.7 0.0 3.6 295.4 0.4 1.9 1.3 3.4 1.2 13.3 11.4 1.2 40.6 0.2 8.9 4.4 160.4 15.3 1.4 12.6 0.9 11.0 2.3 492.2 1.7 0.2 0.8 16.2 118.4 553.6 7.8 89.8 310.9 65.8 0.0 1505.6 0.2 352.2 0.5 0.1 1.4 1.4 30.1 338.4 1.1 1.2 12.9 36.6 1.0 0.0 182.1 15.9 0.4 1.3 16.7 114.7 6.4 310.1 92.7 3.2 67.3 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LYL1 bHLHa18 ENSG00000104903 "LYL1 basic helix-loop-helix family member" P12980 19 13099033-13103161 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.9;lymphoid tissue: 36.7" "Cell type enhanced" "Detected in many" "Early spermatids: 335.4;Erythroid cells: 298.9;Late spermatids: 763.9;Spermatocytes: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.4" "Group enriched" "Detected in many" 4 "B-cells: 3.7;granulocytes: 6.4;monocytes: 2.8" "Cell line enhanced" "Detected in many" "HEL: 127.7;HL-60: 90.5;HMC-1: 206.6;K-562: 102.1;NB-4: 131.9;REH: 96.5;THP-1: 86.1;U-937: 86.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA072177 Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA072177: " "unprognostic (8.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.27e-2)" "unprognostic (3.29e-3)" "unprognostic (2.76e-1)" "unprognostic (3.64e-3)" "unprognostic (2.46e-1)" "unprognostic (1.05e-2)" "unprognostic (1.90e-2)" "unprognostic (5.87e-2)" "unprognostic (1.78e-3)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.18e-1)" "unprognostic (6.54e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-1)" 9.7 4.1 6.3 10.9 6.0 35.9 7.3 7.1 7.5 6.7 4.9 6.4 2.0 7.7 0.3 3.2 5.8 1.4 10.1 6.4 6.4 5.7 2.6 12.3 12.3 8.9 6.8 2.8 2.0 0.5 2.5 5.6 8.1 5.7 0.6 0.0 3.7 1.3 2.8 3.2 14.1 1.8 9.1 36.7 4.1 20.8 9.0 2.3 5.3 1.9 6.2 7.8 5.6 9.6 0.1 0.3 0.2 0.0 0.0 0.3 0.0 1.4 0.2 0.4 0.1 0.5 0.0 24.8 8.4 0.2 0.0 0.1 0.4 0.0 0.0 14.7 0.0 127.7 0.1 1.2 1.4 90.5 206.6 0.4 0.0 0.1 0.0 0.0 31.9 0.0 102.1 4.4 0.0 0.0 0.5 131.9 0.0 0.4 3.2 96.5 0.3 11.2 0.0 0.0 0.1 9.1 2.8 0.0 6.0 0.0 0.0 86.1 51.8 0.0 0.1 3.6 0.1 0.0 0.0 20.3 0.1 86.1 0.1 2.4 1.4 6.4 0.0 1.9 0.1 2.1 0.2 0.1 1.0 3.7 0.1 0.1 2.4 0.0 2.8 0.3 0.4 0.4 6.3 6.0 7.1 7.5 6.4 6.4 8.9 6.8 8.1 9.1 9.0 9.6 33.7 0.0 0.5 0.0 80.1 2.5 0.5 0.1 0.6 0.0 1.0 1.4 2.3 2.8 0.2 1.8 0.0 0.7 6.6 1.6 0.0 0.4 335.4 0.4 1.9 40.1 1.8 298.9 0.4 0.0 1.3 3.2 1.1 0.2 45.1 0.8 32.9 1.1 113.2 0.0 0.3 1.2 0.0 60.3 35.1 763.9 8.1 68.3 7.2 13.1 36.4 1.5 4.1 0.5 1.3 2.0 1.6 12.0 6.3 0.4 1.7 0.5 1.7 0.2 13.1 1.8 2.2 120.6 5.8 1.4 1.8 1.5 9.0 0.5 1.0 0.6 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 MAD1L1 "HsMAD1, MAD1, PIG9, TP53I9, TXBP181" ENSG00000002822 "Mitotic arrest deficient 1 like 1" Q9Y6D9 7 1815793-2233243 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 316.9;Late spermatids: 685.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003635, CAB015338" Supported Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "CAB015338: AB_627901, HPA003635: AB_1853472" "unprognostic (1.85e-1)" "unprognostic (3.76e-2)" "unprognostic (4.26e-3)" "unprognostic (8.32e-2)" "unprognostic (1.42e-2)" "unprognostic (3.83e-2)" "unprognostic (2.70e-2)" "unprognostic (1.18e-2)" "unprognostic (4.78e-2)" "unprognostic (5.76e-2)" "unprognostic (1.89e-1)" "unprognostic (2.48e-1)" "unprognostic (2.33e-3)" "unprognostic (5.18e-2)" "unprognostic (1.33e-1)" "unprognostic (2.36e-1)" "unprognostic (4.57e-1)" 9.4 6.0 6.2 11.1 8.3 14.9 9.0 4.6 8.4 11.4 5.1 7.7 6.0 9.3 2.5 9.2 7.4 4.8 8.8 5.6 6.7 6.5 6.4 10.2 17.8 7.8 6.6 7.4 5.6 4.1 7.1 5.0 7.6 8.2 3.4 4.0 7.3 5.6 13.6 14.5 9.7 5.3 5.5 18.2 6.6 10.7 7.0 15.3 8.6 5.0 10.7 8.3 10.1 9.4 37.2 15.5 16.5 30.1 11.1 11.2 26.5 25.6 13.0 26.0 20.7 28.5 21.5 23.4 10.4 14.7 39.9 28.5 12.4 18.3 15.7 11.1 17.8 30.1 19.4 45.0 15.7 21.1 55.1 13.9 13.3 28.8 14.0 6.3 14.9 13.7 30.3 17.4 10.3 45.4 8.7 61.0 30.7 5.8 20.5 38.5 16.7 17.5 12.7 18.7 10.7 33.4 20.0 24.9 65.2 11.2 17.1 48.9 17.6 21.8 60.0 62.3 26.0 30.3 31.4 27.3 18.1 60.6 80.3 60.4 36.2 25.4 71.3 62.4 66.6 54.6 69.2 72.3 63.4 63.0 92.0 66.0 8.6 22.7 60.1 26.0 131.5 53.6 6.2 8.3 4.6 8.4 5.6 6.7 7.8 6.6 7.6 5.5 7.0 9.4 9.3 3.2 10.4 12.1 33.8 17.6 13.9 14.0 15.4 8.3 6.2 6.5 7.4 14.3 11.9 7.3 10.4 16.2 35.7 12.4 15.6 12.3 316.9 5.5 6.7 10.7 32.4 19.1 20.9 11.4 16.3 11.4 11.7 6.9 41.8 15.5 6.4 36.4 39.6 23.5 24.4 9.4 16.2 31.4 84.1 685.9 12.5 28.2 37.4 21.5 25.7 24.3 47.4 16.1 32.4 16.5 7.9 10.5 14.9 9.4 5.4 15.2 6.6 13.9 19.7 11.2 10.2 60.3 33.8 9.3 21.5 24.5 43.1 17.5 8.8 9.7 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 32.8;Plasma cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 35.8 21.4 5.3 54.6 6.4 83.6 24.8 6.6 5.9 19.6 18.5 30.3 31.0 21.8 9.0 19.8 19.9 28.4 16.0 4.9 7.4 17.3 23.7 46.8 52.1 10.3 6.7 16.7 39.7 16.6 9.9 24.6 9.5 20.5 22.6 1.6 35.2 14.9 12.1 28.9 33.6 20.2 8.9 70.1 32.7 6.4 9.7 23.1 16.3 9.4 39.3 35.6 16.7 12.4 52.4 26.3 26.4 31.3 85.8 57.3 74.0 37.9 79.2 33.1 32.4 21.3 21.4 56.9 44.9 30.4 9.4 40.1 13.6 25.6 15.7 28.5 41.6 19.8 13.6 34.9 43.5 131.6 130.2 68.5 49.2 18.5 23.3 35.6 31.7 21.1 25.6 41.9 17.8 40.9 17.9 74.2 21.9 26.2 32.8 40.8 36.1 28.8 38.9 59.8 8.2 25.5 37.7 32.0 63.0 15.8 49.4 80.0 42.0 44.8 18.4 44.0 36.2 55.4 65.5 28.0 30.4 127.5 51.2 12.2 201.8 29.7 31.9 178.8 35.4 32.9 28.9 29.0 158.8 26.4 15.4 15.9 29.4 13.2 138.4 187.5 30.7 150.3 5.3 6.4 6.6 5.9 4.9 7.4 10.3 6.7 9.5 8.9 9.7 12.4 1.6 6.4 7.5 8.5 25.1 3.6 2.0 2.7 14.2 2.6 1.9 1.0 0.9 2.8 2.0 1.8 0.0 2.5 20.5 2.0 1.9 1.7 3.7 1.4 2.5 3.1 1.8 9.4 7.8 2.3 2.8 7.2 20.9 1.3 1.3 3.4 1.8 0.8 8.4 0.0 6.4 0.9 0.0 15.4 24.7 11.1 3.7 32.8 1.8 17.8 11.0 1.5 9.2 3.5 13.4 1.5 2.5 4.5 78.1 2.5 3.8 1.5 3.9 4.0 13.1 2.3 2.0 0.6 1.6 11.5 3.3 2.7 9.4 2.7 2.0 2.0 MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 7.6;Kupffer cells: 15.1;Macrophages: 15.5;monocytes: 26.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Group enriched" "Detected in many" 4 "granulocytes: 8.3;monocytes: 5.7" "Cell line enriched" "Detected in some" 6 "THP-1: 6.6" "Not detected" "Not detected" HPA077497 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA077497: " "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-2)" "unprognostic (2.01e-1)" "unprognostic (2.49e-2)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" "unprognostic (8.89e-2)" "unprognostic (3.27e-1)" "unprognostic (7.58e-7)" "unprognostic (1.08e-1)" "unprognostic (7.16e-4)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" 2.4 0.6 0.1 6.5 0.2 6.1 0.3 0.4 1.0 0.2 0.3 0.4 0.5 0.2 0.2 0.3 0.6 1.0 0.5 0.3 0.1 0.4 0.7 4.0 0.4 0.3 0.2 0.1 0.2 0.0 0.2 0.8 0.5 0.2 0.3 0.2 0.3 0.0 0.7 0.2 0.6 1.0 0.0 8.9 0.4 1.3 0.3 0.4 0.3 0.3 0.3 1.8 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 1.1 0.0 2.4 3.2 0.1 0.0 3.4 0.0 0.1 0.1 0.0 1.7 0.2 0.0 0.1 8.3 0.3 5.7 0.1 0.0 1.2 0.1 0.2 0.4 1.0 0.3 0.1 0.3 0.2 0.5 0.0 0.3 0.4 0.2 0.0 1.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 7.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.4 0.2 1.0 0.0 0.1 0.0 0.0 15.1 2.4 0.3 0.0 15.5 0.0 0.0 26.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.3 0.7 0.0 0.1 0.0 0.6 0.0 0.0 0.1 MEI1 "MGC40042, SPATA38" ENSG00000167077 "Meiotic double-stranded break formation protein 1" Q5TIA1 22 41699503-41799456 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.4;testis: 39.5" "Cell type enhanced" "Detected in many" "B-cells: 32.8;Early spermatids: 61.3;Late spermatids: 50.8;NK-cells: 29.9;Plasma cells: 94.7;Spermatocytes: 38.1;T-cells: 28.4" "Cancer enhanced" "Detected in many" "cervical cancer: 5.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HeLa: 11.6;HMC-1: 8.5;Karpas-707: 26.8;U-266/70: 29.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 7 "olfactory bulb: 1.4" HPA049240 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA049240: AB_2680689" "unprognostic (1.95e-3)" "prognostic favorable (1.59e-6)" "unprognostic (6.13e-3)" "unprognostic (1.86e-2)" "unprognostic (9.70e-2)" "unprognostic (2.97e-3)" "unprognostic (9.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" "unprognostic (5.96e-2)" "unprognostic (9.65e-2)" "unprognostic (2.62e-1)" "unprognostic (2.45e-10)" "unprognostic (2.82e-1)" "unprognostic (3.02e-1)" "unprognostic (1.85e-1)" "unprognostic (7.39e-2)" 1.3 1.0 2.3 6.7 4.0 12.1 3.0 2.1 2.9 1.5 1.7 6.4 2.6 0.7 0.3 1.6 1.8 1.3 1.0 2.1 2.2 2.8 1.4 4.5 6.6 2.5 3.5 0.8 0.6 0.1 0.9 0.8 2.3 1.5 3.0 1.3 7.0 0.5 0.5 1.2 8.5 0.8 2.1 22.4 4.4 39.5 4.9 2.5 2.3 0.1 8.1 2.7 1.3 2.6 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 2.3 0.0 0.3 0.6 0.2 0.5 0.5 0.2 0.2 0.2 0.0 0.0 0.0 6.7 0.0 2.0 11.6 1.3 1.8 1.4 8.5 0.1 0.1 0.0 0.0 0.3 0.5 0.8 0.4 26.8 0.1 0.0 0.0 6.5 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 3.7 1.0 0.5 0.0 0.0 0.1 29.9 5.1 1.2 0.4 2.8 0.1 18.5 7.2 15.7 29.9 5.6 29.1 21.7 30.1 25.8 6.5 15.4 21.7 24.0 1.3 16.9 2.3 2.3 57.2 18.1 2.3 4.0 2.1 2.9 2.1 2.2 2.5 3.5 2.3 2.1 4.9 2.6 0.7 0.0 3.2 0.0 32.8 0.9 0.3 0.3 0.0 0.6 0.3 0.3 0.9 0.0 0.1 0.0 0.0 0.1 19.9 0.0 0.0 0.1 61.3 0.3 1.0 1.4 0.0 0.4 2.1 0.0 0.2 2.0 2.0 0.1 14.0 0.5 3.3 0.5 7.0 0.0 1.1 2.9 0.0 1.2 3.5 50.8 0.6 11.1 17.8 3.7 15.5 0.1 29.9 1.0 1.1 5.3 0.0 1.2 94.7 0.3 0.1 0.4 0.1 1.1 0.0 0.7 1.7 38.1 26.1 0.0 1.0 0.0 28.4 0.1 0.4 0.3 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 NAIF1 "bA379C10.2, C9orf90, DKFZp762G199" ENSG00000171169 "Nuclear apoptosis inducing factor 1" Q69YI7 9 128061233-128068206 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054898, HPA064931" Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA054898: AB_2682633, HPA064931: AB_2732725" "unprognostic (7.09e-2)" "unprognostic (5.92e-2)" "unprognostic (1.20e-2)" "unprognostic (5.56e-3)" "unprognostic (1.58e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.60e-1)" "unprognostic (6.15e-2)" "unprognostic (9.41e-2)" "prognostic favorable (1.02e-5)" "unprognostic (3.08e-1)" "prognostic favorable (8.30e-5)" "unprognostic (8.48e-2)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (3.92e-2)" 2.0 2.4 1.2 1.8 1.4 4.3 1.8 1.2 1.6 2.1 1.3 2.0 2.0 2.2 0.7 2.6 1.8 1.0 2.0 1.2 1.2 1.7 2.6 1.6 2.6 1.4 1.2 1.7 2.4 1.8 1.5 1.6 1.3 1.5 1.2 0.7 2.2 1.4 2.7 2.3 2.3 1.4 1.1 3.2 2.1 3.4 1.6 2.4 1.7 1.9 2.2 1.6 1.8 1.2 5.1 4.4 2.7 7.0 2.5 2.2 6.1 3.8 2.3 3.2 2.6 3.5 4.0 6.2 3.3 2.4 4.5 3.8 2.8 2.9 2.6 19.1 3.8 4.6 5.4 2.0 4.1 6.4 12.5 2.0 3.4 2.5 4.0 2.6 2.9 6.9 11.0 3.9 3.0 5.9 6.2 7.7 3.0 6.9 7.4 5.9 4.3 5.7 2.5 3.1 3.9 4.5 3.8 5.2 4.0 2.0 4.0 6.3 2.0 3.8 11.8 3.2 4.5 6.3 14.0 4.1 3.6 4.1 5.1 0.0 0.7 1.2 0.5 0.6 0.4 0.3 1.1 0.7 0.7 0.9 0.7 0.6 1.5 0.5 1.0 0.5 0.3 0.5 1.2 1.4 1.2 1.6 1.2 1.2 1.4 1.2 1.3 1.1 1.6 1.2 5.6 0.0 3.0 2.0 5.4 4.8 4.6 3.9 4.6 4.0 3.9 2.8 4.2 4.3 3.4 5.5 0.0 5.8 6.6 6.3 3.9 3.5 8.7 2.6 3.5 6.4 5.4 0.8 1.0 6.6 5.7 3.1 1.5 3.2 8.2 3.7 7.1 2.4 5.7 10.1 0.9 4.0 0.0 7.0 3.6 10.9 6.2 3.1 0.0 0.0 5.1 4.6 7.2 2.0 0.7 3.7 5.1 3.0 3.4 3.3 7.3 4.2 1.8 5.0 0.0 4.2 3.5 15.1 7.8 5.0 3.8 4.7 4.0 4.4 3.6 2.9 NCF1 "NCF1A, NOXO2, p47phox, SH3PXD1A" ENSG00000158517 "Neutrophil cytosolic factor 1" P14598 7 74773962-74789376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.4;lymphoid tissue: 97.5" "Cell type enhanced" "Detected in many" "B-cells: 293.0;dendritic cells: 157.3;Kupffer cells: 119.9;Macrophages: 153.4;monocytes: 329.9;Plasma cells: 205.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1165.0;classical monocyte: 673.5;eosinophil: 1467.3;neutrophil: 2128.0" "Group enriched" "Detected in all" 5 "granulocytes: 2128.0;monocytes: 673.5" "Group enriched" "Detected in some" 5 "Daudi: 96.2;HMC-1: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004524, HPA047836, HPA052095" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB004524: AB_627987, HPA047836: AB_2680173, HPA052095: AB_2681721" "unprognostic (4.93e-2)" "unprognostic (8.34e-3)" "unprognostic (1.23e-1)" "unprognostic (1.25e-2)" "unprognostic (8.67e-2)" "unprognostic (3.55e-3)" "unprognostic (7.60e-2)" "unprognostic (4.75e-2)" "unprognostic (6.23e-3)" "unprognostic (9.99e-2)" "unprognostic (6.61e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-3)" "unprognostic (3.16e-1)" "unprognostic (4.17e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-1)" 7.5 3.8 1.9 38.7 2.2 86.4 2.7 4.6 2.9 1.7 0.9 7.2 7.6 1.3 0.5 3.3 3.2 5.5 3.0 2.8 2.0 2.9 5.0 17.7 56.8 5.0 3.4 1.1 1.5 0.7 1.2 5.0 4.5 2.1 4.5 1.6 4.2 1.4 1.5 1.8 26.6 4.0 2.4 97.5 6.6 0.8 2.3 7.5 2.6 4.8 37.5 7.6 1.8 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.1 96.2 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.5 0.6 2.9 1.4 0.9 0.0 0.8 130.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.1 16.8 0.3 0.0 0.0 1.6 0.0 3.4 0.2 0.4 0.0 0.1 0.0 0.1 0.1 0.1 0.0 20.6 0.2 0.1 0.3 0.2 0.0 0.6 0.3 16.5 0.2 8.1 0.2 1165.0 673.5 1467.3 4.2 242.3 9.8 257.0 10.0 6.7 77.7 276.6 15.4 9.4 2128.0 10.7 60.2 280.9 11.1 514.1 1.9 2.2 4.6 2.9 2.8 2.0 5.0 3.4 4.5 2.4 2.3 6.6 5.0 0.0 2.8 0.0 293.0 3.1 1.1 29.6 5.2 0.2 3.1 3.2 0.6 4.3 10.9 3.7 0.0 0.6 157.3 0.0 0.0 1.3 8.7 0.8 1.0 3.6 0.0 6.1 0.0 0.6 12.2 1.5 10.2 2.5 14.5 0.1 3.9 3.6 39.3 3.3 0.1 0.3 2.0 119.9 23.4 6.4 0.0 153.4 10.6 1.0 329.9 0.3 10.3 0.0 0.1 1.2 4.2 0.4 205.7 1.0 0.4 1.9 17.6 0.5 0.0 1.4 1.5 0.2 0.7 5.0 1.7 4.5 63.6 0.1 0.3 2.2 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 NCR3 "1C7, CD337, LY117, NKp30" ENSG00000204475 "Natural cytotoxicity triggering receptor 3" O14931 6 31588895-31593006 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 4.0;intestine: 5.6;lymphoid tissue: 16.1" "Group enriched" "Detected in some" 10 "B-cells: 43.6;dendritic cells: 110.4;NK-cells: 166.9;T-cells: 55.5" "Cancer enhanced" "Detected in many" "testis cancer: 2.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 274.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 2.0;HEL: 2.7;NB-4: 10.9;U-698: 1.7" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.99e-3)" "unprognostic (9.23e-4)" "unprognostic (1.23e-3)" "unprognostic (2.49e-4)" "unprognostic (2.15e-1)" "unprognostic (2.57e-4)" "unprognostic (5.99e-2)" "unprognostic (1.15e-2)" "unprognostic (1.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-1)" "unprognostic (1.81e-1)" "unprognostic (2.21e-4)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (8.17e-2)" "unprognostic (1.43e-1)" 0.5 0.0 0.0 2.9 0.0 4.0 0.2 0.0 0.1 0.1 0.0 0.4 0.3 0.2 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 1.0 1.8 5.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.2 5.6 0.0 0.0 16.1 0.4 0.7 0.1 2.0 0.3 0.0 4.9 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.2 0.5 0.0 98.8 0.1 274.3 65.2 12.1 53.9 0.3 51.8 5.7 30.1 0.9 76.6 0.6 0.6 20.3 31.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.7 0.0 1.9 0.0 43.6 3.4 0.0 0.0 0.6 0.0 0.3 0.4 0.1 0.0 1.3 0.0 0.0 0.1 110.4 0.1 0.0 0.0 0.5 0.1 0.2 0.5 0.0 2.7 0.0 0.0 0.2 0.3 0.5 0.1 8.9 0.0 1.4 0.4 0.4 0.0 0.0 0.0 0.0 2.5 2.9 0.2 0.3 1.2 3.6 0.0 1.6 0.0 166.9 0.0 0.1 0.0 0.1 0.0 2.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.6 0.7 0.1 1.7 0.1 55.5 0.0 0.1 0.0 NFATC2IP "ESC2, FLJ14639, NIP45, RAD60" ENSG00000176953 "Nuclear factor of activated T cells 2 interacting protein" Q8NCF5 16 28950807-28967097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053587 Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053587: AB_2682202" "unprognostic (6.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.48e-2)" "unprognostic (1.33e-1)" "unprognostic (4.90e-1)" "unprognostic (7.09e-2)" "unprognostic (8.82e-3)" "unprognostic (1.15e-2)" "unprognostic (8.95e-2)" "unprognostic (5.80e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (5.23e-4)" "prognostic unfavorable (1.03e-5)" "unprognostic (8.00e-2)" "unprognostic (3.85e-2)" "unprognostic (3.25e-1)" "unprognostic (5.94e-2)" 20.9 16.6 10.4 27.6 10.5 48.6 21.7 15.6 11.0 25.2 9.9 30.6 21.1 23.3 14.4 29.0 24.5 14.3 20.9 11.0 9.1 26.0 27.9 25.8 36.6 11.1 10.6 24.1 22.7 20.0 15.0 15.5 11.1 23.9 32.2 26.6 24.3 15.5 25.7 32.5 36.9 22.8 9.8 45.4 25.9 30.3 12.1 34.3 22.0 15.8 38.5 26.0 23.5 11.7 38.6 27.2 36.5 36.7 21.7 22.8 46.0 36.7 27.6 42.1 53.7 32.0 47.0 41.1 27.0 26.4 25.6 44.8 44.3 40.3 56.9 35.0 32.4 37.5 81.2 39.8 13.9 34.1 55.0 16.1 32.1 45.9 27.6 20.8 34.3 40.9 34.4 49.5 37.8 47.9 44.9 60.2 35.9 30.9 32.0 77.0 32.4 37.5 30.2 34.2 28.0 20.0 24.7 37.7 14.4 29.6 39.1 25.2 38.1 46.3 26.1 36.5 28.1 36.5 51.5 49.7 25.6 55.5 27.8 5.0 1.5 1.8 1.9 2.0 1.8 1.5 1.4 2.3 0.9 1.5 2.3 2.0 1.1 2.8 1.2 3.2 2.4 0.7 10.4 10.5 15.6 11.0 11.0 9.1 11.1 10.6 11.1 9.8 12.1 11.7 40.9 35.3 52.2 15.7 43.1 31.7 23.0 19.1 33.0 63.1 29.4 25.7 17.4 21.5 29.8 29.5 100.1 30.1 69.8 51.3 19.6 21.9 6.3 28.3 43.6 35.1 40.9 77.2 21.3 22.9 30.5 23.3 50.0 37.6 36.7 69.5 38.9 26.0 23.2 43.7 27.0 63.1 18.3 38.8 32.2 7.6 29.5 37.8 23.2 26.2 56.7 15.3 57.7 19.6 18.2 44.6 31.6 20.3 55.4 40.4 40.7 17.8 21.7 84.5 39.5 26.7 26.6 95.0 92.2 35.7 30.3 26.1 51.4 38.3 53.0 42.1 NFKB2 "LYT-10, NF-kB2, p105, p49/p100, p52" ENSG00000077150 "Nuclear factor kappa B subunit 2" Q00653 10 102394110-102402524 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 122.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 168.0;Karpas-707: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008422, CAB022098, HPA023900" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoplasm "CAB022098: , HPA008422: AB_1854434, HPA023900: AB_1854435" "unprognostic (1.10e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (1.53e-2)" "unprognostic (8.08e-3)" "unprognostic (2.15e-1)" "unprognostic (2.38e-3)" "unprognostic (3.98e-2)" "prognostic favorable (8.45e-5)" "unprognostic (4.04e-1)" "unprognostic (8.34e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.69e-12)" "unprognostic (2.37e-3)" "unprognostic (1.63e-1)" "unprognostic (4.90e-2)" "unprognostic (1.56e-1)" 26.5 21.0 7.6 44.4 7.4 69.3 19.6 7.1 9.2 22.9 8.5 39.1 15.5 21.6 2.3 17.7 20.4 18.5 20.6 7.2 7.2 34.6 28.2 41.0 40.7 8.5 7.5 21.4 24.1 6.1 10.8 14.7 8.0 29.0 6.8 1.1 21.3 9.1 18.4 20.0 26.5 12.2 7.5 50.6 22.7 10.0 8.4 16.9 20.1 7.6 25.7 37.0 19.1 8.0 67.9 48.6 7.7 31.7 11.1 16.6 19.3 18.5 61.0 19.6 25.9 28.6 55.2 32.9 43.5 11.9 48.8 40.9 20.5 28.2 6.8 168.0 11.2 7.0 11.7 15.9 30.1 5.1 45.5 22.0 14.6 34.1 32.3 26.5 7.8 16.1 7.6 157.8 7.4 26.4 7.1 22.7 10.3 15.7 16.6 16.8 24.5 27.0 34.3 22.1 1.7 8.2 16.2 36.7 26.3 7.2 29.3 16.4 21.2 19.0 28.9 25.4 47.0 113.1 105.0 32.6 31.1 14.8 10.9 0.0 1.3 0.0 0.7 0.9 0.7 2.6 0.8 0.7 0.7 2.1 0.8 0.8 5.6 0.8 2.1 0.6 1.1 0.5 7.6 7.4 7.1 9.2 7.2 7.2 8.5 7.5 8.0 7.5 8.4 8.0 20.8 9.6 8.8 3.3 88.3 43.5 59.3 41.2 34.7 2.2 17.1 14.5 3.1 25.8 29.9 18.4 16.7 6.3 39.0 33.3 5.9 33.2 1.1 33.7 14.4 26.1 16.3 0.4 0.1 21.0 15.8 26.0 80.0 52.0 71.8 5.5 11.7 3.7 20.9 0.0 0.1 30.4 22.4 19.4 122.9 1.7 7.5 52.5 30.2 1.9 75.1 3.9 12.3 1.5 0.7 44.9 37.4 4.9 49.1 49.3 33.2 8.6 19.9 5.3 0.0 36.4 43.6 4.7 11.1 17.5 44.6 23.1 54.6 8.8 17.9 45.6 NFKBIE IKBE ENSG00000146232 "NFKB inhibitor epsilon" O00221 6 44258166-44265788 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002692, HPA005941, CAB010272" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010272: AB_2235977, HPA002692: AB_1079479, HPA005941: AB_1079478" "prognostic favorable (1.72e-5)" "unprognostic (1.43e-1)" "unprognostic (1.39e-2)" "unprognostic (2.37e-2)" "unprognostic (6.32e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (4.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.43e-2)" "unprognostic (3.36e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (1.37e-6)" "unprognostic (2.61e-2)" "unprognostic (8.83e-2)" "unprognostic (1.37e-2)" "prognostic favorable (8.07e-4)" 6.8 5.8 10.9 19.1 10.8 31.5 5.9 12.1 17.6 4.1 10.7 7.2 7.4 3.7 4.7 5.9 3.3 8.3 5.3 11.3 10.6 16.1 10.5 13.6 19.9 11.5 11.4 2.7 8.3 5.3 4.5 5.5 11.2 8.3 5.9 3.7 7.4 3.3 3.5 9.9 12.1 3.6 11.7 35.0 7.0 10.7 11.8 9.9 5.3 3.9 25.1 16.3 5.0 12.3 28.4 7.9 9.5 15.1 3.7 2.8 5.3 4.9 23.8 14.9 15.4 15.0 12.9 15.7 17.0 5.1 39.7 6.2 10.3 15.4 16.6 26.1 6.0 7.9 3.0 17.0 11.4 26.1 23.0 7.1 6.7 13.8 8.8 12.5 10.7 7.2 7.7 39.2 3.9 14.4 5.2 52.7 5.0 44.1 4.0 9.9 8.5 14.0 34.7 30.3 6.1 7.8 3.4 12.5 20.9 8.0 8.6 29.9 18.1 8.4 9.8 5.3 15.4 25.0 11.4 28.7 7.4 28.4 16.1 8.8 7.5 4.0 1.6 9.4 3.2 8.6 2.2 1.5 6.6 6.5 1.0 1.6 3.0 0.8 11.1 8.1 3.1 1.7 10.9 10.8 12.1 17.6 11.3 10.6 11.5 11.4 11.2 11.7 11.8 12.3 7.5 0.0 9.7 1.0 26.0 38.2 28.7 11.6 14.8 3.4 15.3 9.9 5.4 22.8 9.2 3.7 2.1 5.2 12.5 12.2 17.6 49.5 17.3 10.0 6.2 15.9 14.9 1.7 1.1 21.0 8.0 17.3 10.7 12.8 32.5 2.5 6.1 2.0 57.2 3.3 2.0 11.9 6.1 22.6 151.2 34.1 1.8 48.6 48.0 3.7 55.2 3.3 1.0 0.5 0.9 58.9 33.3 2.6 18.7 32.6 14.3 14.4 6.1 4.1 6.6 11.8 11.0 25.9 12.3 11.6 39.2 5.3 13.8 7.0 8.5 34.7 NIBAN3 "BCNP1, FAM129C, FLJ39802" ENSG00000167483 "Niban apoptosis regulator 3" Q86XR2 19 17523301-17553839 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "bone marrow: 15.4;intestine: 16.6;lymphoid tissue: 34.7" "Cell type enriched" "Detected in some" 8 "B-cells: 11.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 31.9;naive B-cell: 52.1;plasmacytoid DC: 110.7" "Group enriched" "Detected in many" 476 "B-cells: 52.1;dendritic cells: 110.7" "Group enriched" "Detected in some" 19 "Daudi: 50.1;REH: 23.8;U-698: 33.2" "Not detected" "Not detected" HPA043277 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA043277: AB_10794391" "unprognostic (6.55e-5)" "unprognostic (3.03e-7)" "unprognostic (3.40e-1)" "unprognostic (1.62e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-4)" "unprognostic (3.79e-3)" "unprognostic (1.69e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-1)" "unprognostic (9.47e-4)" "unprognostic (8.42e-2)" "unprognostic (5.51e-5)" "unprognostic (3.39e-1)" "unprognostic (9.03e-3)" "unprognostic (6.08e-2)" "unprognostic (7.56e-3)" 0.4 0.0 0.0 10.7 0.1 15.4 0.1 0.0 0.2 0.1 0.0 0.8 0.0 0.1 0.0 0.4 0.1 1.0 0.1 0.0 0.0 0.5 0.3 0.4 26.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.0 16.6 0.0 0.0 34.7 0.7 0.5 0.0 1.8 0.6 0.0 12.2 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 0.0 0.0 0.0 52.1 0.0 0.1 0.0 0.0 0.0 110.7 0.0 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;lung: 6.2;lymphoid tissue: 11.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 11.9;Kupffer cells: 21.0;Macrophages: 14.5;Microglial cells: 10.3;monocytes: 18.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "classical monocyte: 49.3;intermediate monocyte: 56.9;myeloid DC: 32.2;neutrophil: 24.6;non-classical monocyte: 44.2" "Group enriched" "Detected in many" 32 "dendritic cells: 32.2;granulocytes: 24.6;monocytes: 56.9" "Cell line enhanced" "Detected in some" "HL-60: 3.1" "Not detected" "Not detected" "HPA006592, HPA075894" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA006592: AB_2667620, HPA075894: " "unprognostic (7.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.88e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-2)" "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (6.33e-2)" "unprognostic (6.33e-2)" "unprognostic (6.03e-6)" "unprognostic (7.42e-2)" "unprognostic (2.06e-3)" "unprognostic (2.02e-2)" "unprognostic (1.63e-1)" 3.4 1.4 0.4 8.7 0.5 8.3 0.7 0.4 0.8 0.6 0.6 0.9 0.9 0.4 0.0 0.6 0.8 1.4 1.2 0.4 0.4 0.5 1.6 6.2 2.3 0.6 0.5 0.3 0.8 0.1 0.6 2.1 0.6 0.4 0.8 0.6 0.5 0.2 1.0 0.3 1.3 2.3 0.5 11.4 0.6 0.4 0.9 0.7 0.4 0.3 1.2 2.0 0.3 0.8 0.1 0.2 0.3 0.7 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.3 0.5 0.1 0.4 0.0 3.1 0.5 0.0 0.3 0.0 1.4 0.4 0.0 0.1 0.3 0.2 0.0 0.0 0.2 1.4 0.1 0.2 0.2 0.1 0.4 0.5 0.0 0.3 0.3 0.7 0.2 0.2 1.2 0.5 0.1 1.4 0.1 0.3 0.3 0.2 0.4 0.3 0.8 1.2 0.4 1.3 0.4 0.5 49.3 5.8 0.1 56.9 0.4 0.6 0.0 0.0 32.2 1.1 0.0 0.1 24.6 0.3 44.2 0.4 0.2 18.6 0.4 0.5 0.4 0.8 0.4 0.4 0.6 0.5 0.6 0.5 0.9 0.8 0.2 0.0 1.8 1.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.7 4.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 1.1 0.0 11.9 0.0 3.3 0.0 0.0 21.0 1.0 0.0 0.0 14.5 0.0 10.3 18.4 0.0 1.0 1.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 NLRC5 "CLR16.1, FLJ21709, NOD27" ENSG00000140853 "NLR family CARD domain containing 5" Q86WI3 16 56989485-57083531 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.6;lymphoid tissue: 32.8" "Cell type enhanced" "Detected in many" "dendritic cells: 35.8;Distal enterocytes: 43.2;Gastric mucus-secreting cells: 41.8;NK-cells: 39.1;T-cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 94.2;NB-4: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060405, HPA074724" Supported Centrosome,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol Centrosome "HPA060405: AB_2684277, HPA074724: " "unprognostic (9.66e-2)" "prognostic favorable (9.69e-4)" "unprognostic (1.64e-2)" "unprognostic (1.23e-2)" "unprognostic (3.12e-1)" "unprognostic (9.27e-3)" "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "unprognostic (2.24e-2)" "prognostic favorable (2.30e-4)" "unprognostic (2.69e-1)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.99e-2)" "unprognostic (3.91e-2)" "unprognostic (5.06e-2)" "unprognostic (2.75e-3)" 5.8 3.6 2.4 24.1 2.9 34.6 2.9 2.1 2.6 2.7 1.2 8.5 6.0 4.2 1.5 5.5 2.7 8.4 4.1 1.8 2.5 2.4 2.6 11.3 28.9 7.4 3.1 2.8 2.6 3.0 4.8 2.7 5.5 2.9 6.8 0.7 8.6 2.5 3.1 13.6 8.8 6.0 3.3 32.8 9.2 1.2 4.1 10.6 2.8 4.8 17.3 7.0 2.7 3.7 11.3 2.1 0.3 0.8 0.7 3.6 0.1 6.1 9.4 19.1 18.4 0.0 19.0 22.9 4.5 10.0 7.5 7.3 2.4 0.6 2.1 1.0 0.7 94.2 21.8 2.3 6.5 3.3 5.4 7.0 0.2 15.6 1.7 6.1 7.5 3.2 0.1 4.5 4.0 0.4 5.2 51.8 0.1 0.3 2.0 24.5 6.9 9.4 2.1 0.9 0.7 0.8 12.4 1.1 2.6 0.0 1.3 12.3 9.7 9.1 3.2 33.7 5.1 9.0 5.0 23.9 16.3 6.9 1.7 7.2 3.8 12.6 5.8 1.9 3.5 4.6 3.4 5.7 1.5 2.7 2.1 2.3 8.5 2.3 2.3 1.1 4.1 3.0 2.4 2.9 2.1 2.6 1.8 2.5 7.4 3.1 5.5 3.3 4.1 3.7 29.8 0.0 11.2 6.2 28.0 6.8 0.9 1.1 2.2 0.9 3.1 2.8 5.3 0.0 3.6 5.5 0.0 0.1 35.8 43.2 0.0 5.6 0.5 5.1 8.5 16.9 8.4 4.8 0.5 8.4 0.2 3.4 41.8 16.7 9.5 2.2 7.9 5.5 4.5 0.0 0.8 20.7 4.1 16.2 5.4 0.5 0.9 14.2 0.0 26.2 17.8 0.2 39.1 1.5 4.5 9.4 14.1 0.4 14.7 2.3 3.0 0.9 2.5 1.3 0.0 3.7 6.4 0.1 0.1 3.3 9.9 0.1 42.2 7.8 15.9 3.5 NOL9 "FLJ23323, Grc3, NET6" ENSG00000162408 "Nucleolar protein 9" Q5SY16 1 6521347-6554513 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Kinase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036347 Supported "Nucleoli,Intermediate filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoli "Intermediate filaments" "HPA036347: AB_2675076" "unprognostic (3.03e-1)" "unprognostic (4.93e-2)" "unprognostic (4.99e-2)" "unprognostic (3.14e-3)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (2.48e-1)" "unprognostic (1.31e-1)" "unprognostic (8.90e-2)" "unprognostic (1.44e-3)" "unprognostic (2.32e-1)" "unprognostic (3.80e-2)" "unprognostic (3.32e-2)" "unprognostic (3.40e-1)" "unprognostic (3.54e-2)" "unprognostic (4.65e-2)" 3.8 4.6 4.5 3.5 5.0 7.5 3.7 4.9 5.6 4.7 1.9 5.0 2.4 5.0 3.6 4.7 4.3 2.3 4.5 6.2 4.2 4.4 5.3 3.2 5.2 3.3 3.8 4.8 6.0 3.4 4.0 3.0 3.8 4.1 3.1 4.3 3.6 3.1 7.0 6.0 4.8 3.9 2.7 8.8 4.5 3.7 4.6 3.8 3.4 4.5 5.1 4.5 3.8 4.0 6.4 9.1 5.0 15.2 6.6 4.0 5.4 6.3 4.1 6.4 6.8 12.6 8.6 17.9 7.3 7.1 5.5 8.3 10.2 8.6 10.9 7.3 5.5 12.2 14.7 9.9 6.6 10.4 6.4 5.8 2.6 13.6 11.8 3.7 7.6 7.8 14.3 7.3 6.6 11.2 10.2 9.2 6.9 5.0 8.7 12.7 11.7 8.3 5.1 5.8 9.7 4.4 9.7 12.1 8.1 5.1 7.9 4.8 10.0 10.1 8.1 7.2 10.6 6.1 6.2 31.9 9.4 11.4 4.9 3.5 1.9 1.6 3.1 1.9 3.2 2.9 4.5 2.9 1.3 3.7 4.6 3.8 1.2 1.7 3.2 3.5 3.2 1.2 4.5 5.0 4.9 5.6 6.2 4.2 3.3 3.8 3.8 2.7 4.6 4.0 15.0 19.2 19.5 9.4 16.2 15.4 6.9 6.9 10.8 17.1 9.8 13.2 15.0 11.5 7.4 7.3 14.6 14.8 17.3 6.7 15.6 8.9 6.0 13.7 19.7 15.2 6.7 11.6 18.9 8.6 12.6 15.3 11.7 15.6 5.1 18.3 14.3 13.2 9.1 10.1 18.5 10.9 4.1 13.8 7.3 17.0 9.6 8.6 1.8 10.3 13.4 8.1 12.3 13.0 20.1 9.0 6.2 12.8 17.9 7.3 7.6 10.7 9.0 18.2 0.0 22.6 12.7 11.7 21.5 16.0 14.8 12.7 17.3 19.1 13.2 7.3 OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 13.6;lung: 28.4;lymphoid tissue: 29.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 35.6;Kupffer cells: 27.8;Macrophages: 42.9;monocytes: 66.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 36 "classical monocyte: 43.0;eosinophil: 26.6;intermediate monocyte: 28.8;myeloid DC: 20.3;neutrophil: 40.0;non-classical monocyte: 27.0" "Group enriched" "Detected in many" 79 "dendritic cells: 20.3;granulocytes: 40.0;monocytes: 43.0" "Cell line enhanced" "Detected in some" "EFO-21: 13.9;HHSteC: 9.4;hTERT-HME1: 5.0;NB-4: 5.9;U-937: 17.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 84000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (9.09e-2)" "unprognostic (6.79e-3)" "unprognostic (8.47e-3)" "unprognostic (2.14e-1)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "unprognostic (9.69e-2)" "unprognostic (4.28e-2)" 3.7 1.8 0.9 2.3 0.7 13.6 1.8 0.1 1.6 2.2 0.0 1.5 0.0 1.3 0.0 1.5 3.2 1.3 1.9 0.1 0.7 1.5 2.4 28.4 0.3 1.3 0.7 1.1 1.3 0.1 1.0 0.6 0.9 1.7 0.3 0.0 2.2 0.3 0.5 2.1 1.6 1.7 0.7 29.8 1.2 0.9 0.8 0.2 1.1 0.6 0.6 2.2 2.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 13.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 9.4 0.6 0.0 0.0 0.2 0.6 5.0 0.8 0.0 0.0 0.0 0.4 0.1 0.1 0.0 5.9 0.3 0.1 1.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.8 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.6 0.5 17.9 0.0 0.0 43.0 26.6 0.3 28.8 0.1 0.0 0.2 0.4 20.3 0.0 0.1 0.0 40.0 0.0 27.0 0.8 0.2 16.8 0.9 0.7 0.1 1.6 0.1 0.7 1.3 0.7 0.9 0.7 0.8 1.7 0.2 3.2 5.9 0.3 0.3 0.8 0.6 0.7 0.6 0.0 0.7 0.4 0.3 1.5 2.1 0.0 0.0 0.3 0.6 0.1 0.0 0.3 0.0 0.1 0.3 0.9 0.0 1.7 1.9 0.0 0.4 0.6 0.0 0.1 1.3 0.3 0.0 0.0 35.6 0.0 1.0 0.3 0.0 27.8 11.6 0.2 0.0 42.9 0.0 1.0 66.4 0.0 1.0 0.0 0.3 0.4 0.0 0.0 0.4 0.3 0.1 0.2 3.7 0.4 0.0 0.2 0.1 0.6 0.5 0.4 0.1 0.3 0.7 0.4 0.1 0.3 P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1;lymphoid tissue: 36.9" "Group enriched" "Detected in some" 9 "Kupffer cells: 124.4;Macrophages: 53.2;Microglial cells: 66.5;monocytes: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 581.5" "Group enriched" "Detected in many" 6 "granulocytes: 581.5;monocytes: 185.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA049047: AB_2680611" "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" 4.8 3.8 1.6 20.6 1.6 25.1 4.2 1.6 2.2 2.6 2.7 4.5 4.6 1.9 0.8 3.2 3.1 3.9 1.4 1.9 2.0 1.6 8.2 7.6 18.2 3.1 2.4 1.6 1.2 1.6 0.5 3.3 2.8 1.4 6.2 0.1 2.9 3.2 0.7 2.1 11.0 5.3 3.7 36.9 3.1 0.7 4.2 4.5 1.3 3.8 8.4 4.1 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 152.5 137.2 0.3 155.4 0.3 1.5 0.2 0.2 66.4 0.6 0.2 0.3 581.5 0.1 185.6 1.1 0.2 77.6 1.6 1.6 1.6 2.2 1.9 2.0 3.1 2.4 2.8 3.7 4.2 4.0 0.9 0.0 6.1 0.0 1.3 0.0 0.1 0.0 0.0 0.8 0.6 0.6 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 3.6 0.3 0.0 0.2 0.6 0.5 0.0 2.5 0.0 0.7 0.4 7.7 1.7 0.2 0.0 0.0 124.4 4.5 0.0 0.0 53.2 0.0 66.5 63.3 1.1 2.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.0 PARVG ENSG00000138964 "Parvin gamma" Q9HBI0 22 44172956-44219533 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.7;lymphoid tissue: 30.1" "Cell type enhanced" "Detected in many" "B-cells: 56.9;dendritic cells: 51.7;granulocytes: 60.1;Hofbauer cells: 66.7;Kupffer cells: 87.3;Langerhans cells: 53.4;Macrophages: 91.9;monocytes: 62.0;T-cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HL-60: 116.4;NB-4: 44.9;THP-1: 64.7;U-937: 53.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031833, HPA031834" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "HPA031833: AB_2674063, HPA031834: AB_10601242" "unprognostic (9.83e-3)" "unprognostic (2.30e-2)" "unprognostic (2.06e-1)" "prognostic favorable (4.44e-6)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (3.19e-2)" "unprognostic (7.02e-2)" "unprognostic (2.17e-1)" "unprognostic (3.87e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (3.73e-1)" "unprognostic (1.35e-2)" "unprognostic (1.09e-1)" "unprognostic (9.89e-2)" 3.5 2.9 3.7 26.7 3.5 49.7 1.8 4.4 7.1 2.6 4.0 3.1 3.6 2.4 0.6 2.5 2.2 6.2 1.3 3.8 4.7 1.8 3.1 10.4 30.1 8.2 4.9 0.8 1.4 0.5 1.3 3.0 6.9 2.1 3.4 0.2 2.6 1.1 1.2 1.7 12.7 2.9 5.9 28.9 4.4 1.7 7.9 18.4 1.9 0.4 26.8 4.7 1.5 9.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.8 0.0 0.0 0.0 116.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 16.8 44.9 0.1 0.0 0.0 9.2 0.2 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 64.7 0.0 0.0 11.5 0.2 0.0 0.3 0.0 0.3 0.0 53.9 1.9 12.5 62.0 71.3 13.9 57.6 13.9 21.4 8.0 15.2 49.2 20.4 8.9 10.3 72.2 13.1 65.9 33.3 12.1 44.6 3.7 3.5 4.4 7.1 3.8 4.7 8.2 4.9 6.9 5.9 7.9 9.4 1.3 6.4 14.0 1.0 56.9 2.4 0.1 0.0 0.6 0.2 0.7 1.5 1.1 0.0 3.1 0.0 0.0 0.6 51.7 0.1 0.0 0.0 4.2 3.7 0.4 2.9 0.0 10.1 3.9 0.2 0.7 2.3 3.6 2.5 60.1 0.0 3.9 1.3 66.7 0.0 2.9 0.0 0.0 87.3 53.4 2.7 0.0 91.9 5.4 10.3 62.0 0.0 26.8 0.0 1.4 0.0 0.0 0.0 15.9 0.0 0.0 0.5 1.5 0.2 0.0 0.5 0.4 1.1 0.8 0.4 1.8 1.0 48.3 0.0 0.1 0.1 PCED1B "FAM113B, MGC16044" ENSG00000179715 "PC-esterase domain containing 1B" Q96HM7 12 47079603-47236662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 40.1;lymphoid tissue: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 30.3;Excitatory neurons: 32.4;Granulosa cells: 47.8;Hofbauer cells: 37.6;Microglial cells: 60.0;T-cells: 36.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 63.3;K-562: 48.9;SK-BR-3: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043901 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus" Vesicles "HPA043901: AB_10959888" "unprognostic (1.71e-1)" "unprognostic (1.15e-1)" "unprognostic (3.29e-3)" "unprognostic (1.47e-3)" "unprognostic (2.72e-1)" "unprognostic (2.23e-1)" "unprognostic (3.32e-2)" "unprognostic (5.13e-2)" "unprognostic (2.36e-3)" "unprognostic (7.74e-2)" "unprognostic (3.39e-1)" "unprognostic (8.74e-2)" "prognostic unfavorable (4.55e-6)" "unprognostic (4.79e-2)" "unprognostic (3.74e-1)" "unprognostic (3.74e-2)" "prognostic favorable (5.36e-5)" 6.5 40.1 3.4 17.9 3.2 10.6 6.1 2.7 3.3 6.7 2.3 10.1 2.2 8.7 2.0 3.1 9.3 5.9 3.3 2.4 3.7 6.0 3.9 9.1 36.0 4.8 5.3 23.4 2.7 1.2 2.3 3.6 4.4 5.8 2.7 0.8 3.3 2.3 1.3 2.7 12.2 4.5 3.6 29.5 3.8 13.7 4.8 7.1 3.4 1.2 24.1 9.6 5.4 5.0 3.4 63.3 1.5 0.0 0.5 0.0 3.0 2.0 3.5 0.7 0.3 3.2 12.3 11.5 3.4 6.5 1.2 9.2 0.0 9.4 0.0 13.5 0.0 0.4 0.6 1.3 1.3 2.7 0.5 0.2 4.1 1.1 7.1 8.8 2.7 0.8 48.9 10.6 4.4 1.5 0.7 2.3 10.6 7.9 0.9 0.2 1.6 8.2 9.7 5.2 0.4 0.0 5.7 31.0 0.0 3.2 5.7 4.0 0.8 0.2 0.9 0.1 2.2 11.4 8.6 20.3 3.0 8.7 0.3 1.7 1.1 2.8 42.5 2.3 48.3 50.1 50.7 54.1 6.4 35.6 88.8 83.5 4.5 30.1 2.6 38.1 59.1 35.4 3.4 3.2 2.7 3.3 2.4 3.7 4.8 5.3 4.4 3.6 4.8 5.0 3.4 3.2 5.6 30.3 23.6 1.1 0.9 4.2 9.1 2.5 4.4 6.2 0.5 0.0 1.5 1.8 0.0 0.5 21.1 0.2 0.0 3.2 0.9 5.1 1.4 3.4 10.2 0.4 32.4 12.8 9.1 3.1 1.5 10.3 1.3 47.8 9.7 0.3 37.6 0.0 2.2 1.4 0.0 4.3 1.8 2.5 3.7 10.7 1.8 60.0 5.3 0.9 23.7 17.6 0.6 11.7 0.8 0.7 28.1 1.4 0.1 0.4 0.8 0.1 0.0 1.3 4.4 0.7 0.2 2.8 0.6 2.1 36.2 22.4 0.3 4.2 PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Excitatory neurons: 162.1;Oligodendrocyte precursor cells: 513.2;Oligodendrocytes: 338.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.8" "Cell line enhanced" "Detected in all" "TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" 13.8 4.4 8.9 5.8 13.3 9.1 9.5 5.5 8.8 11.3 1.0 7.8 5.9 7.4 6.4 5.2 5.7 10.0 16.2 8.2 8.4 5.0 3.8 18.0 6.8 6.4 7.8 7.5 4.8 5.4 2.9 16.7 5.8 6.0 8.1 13.7 5.5 7.3 6.7 6.7 7.3 9.9 4.9 29.4 4.9 9.9 11.8 4.7 6.3 8.5 4.7 9.0 7.5 11.7 5.4 7.8 18.1 4.3 33.4 35.7 6.3 28.6 19.7 14.9 14.9 6.3 4.7 4.1 5.0 41.4 5.7 2.6 14.6 4.5 16.9 4.2 7.6 7.7 12.2 3.8 12.2 4.6 3.9 27.6 4.3 28.8 4.8 16.3 42.3 6.6 10.0 4.0 16.1 2.2 2.6 4.9 8.4 3.7 2.1 5.3 10.8 3.0 4.4 9.6 4.0 4.9 11.2 2.3 18.6 19.7 1.7 3.2 52.1 31.5 15.2 13.2 12.2 6.3 9.5 5.9 5.5 10.5 17.3 0.1 0.2 0.4 0.2 0.0 0.4 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.1 1.8 0.1 0.2 0.0 0.2 8.9 13.3 5.5 8.8 8.2 8.4 6.4 7.8 5.8 4.9 11.8 11.7 48.3 147.4 46.8 101.9 12.6 21.9 7.5 5.6 2.2 18.4 6.1 5.8 46.9 10.0 29.2 1.8 12.5 3.1 12.3 23.9 0.0 6.9 15.1 22.9 19.5 41.2 3.0 10.8 162.1 5.4 2.0 35.6 15.8 10.1 17.7 6.3 31.8 6.0 18.9 20.2 84.4 11.9 2.0 21.3 34.7 13.6 19.9 20.2 12.4 124.6 8.5 28.1 10.3 513.2 338.1 9.8 10.7 16.1 7.0 8.3 15.7 3.7 41.6 20.1 13.1 23.0 37.7 13.6 13.7 5.8 18.0 6.3 8.2 22.6 12.3 7.2 PEAK3 "C19orf35, FLJ45778" ENSG00000188305 "PEAK family member 3" Q6ZS72 19 2274631-2282175 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 4.1" "Cell type enhanced" "Detected in some" "dendritic cells: 1.5;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 41.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 41.0" "Cell line enriched" "Detected in some" 9 "HMC-1: 12.2" "Group enriched" "Detected in some" 5 "basal ganglia: 6.7;cerebellum: 3.1" HPA057806 Uncertain Uncertain Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA057806: AB_2683534" "unprognostic (9.42e-2)" "unprognostic (3.26e-2)" "unprognostic (7.27e-2)" "unprognostic (6.23e-2)" "unprognostic (2.65e-2)" "unprognostic (8.40e-3)" "unprognostic (3.67e-1)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (2.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (1.90e-1)" 0.5 0.4 0.5 1.3 0.9 2.3 0.3 0.5 1.6 0.2 0.1 0.4 0.2 0.2 0.0 0.2 0.5 0.2 0.7 0.4 0.5 0.3 0.2 1.1 0.4 1.4 1.0 0.1 0.2 0.0 0.2 0.1 1.0 0.3 0.2 0.0 0.2 0.0 0.3 0.3 0.8 0.1 0.9 4.1 0.3 0.1 0.8 0.1 0.2 0.0 0.3 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.4 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 10.5 4.4 11.7 1.6 5.7 0.2 0.2 0.1 0.2 1.8 0.4 0.1 0.3 41.0 4.5 1.9 0.2 0.0 1.1 0.5 0.9 0.5 1.6 0.4 0.5 1.4 1.0 1.0 0.9 0.8 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651731-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.9;lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "dendritic cells: 44.0;granulocytes: 25.3;Kupffer cells: 35.2;Microglial cells: 29.0;NK-cells: 29.9;T-cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 153.3;NB-4: 65.9;REH: 68.9;THP-1: 65.4;U-937: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: AB_2679153" "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" 7.2 3.1 6.8 33.4 6.3 60.9 3.9 6.1 7.5 6.2 6.4 5.4 5.2 4.9 1.7 4.9 6.1 7.0 3.3 7.0 5.3 6.4 3.5 12.0 46.9 7.3 6.6 7.0 3.0 2.9 2.8 4.2 7.8 4.6 3.4 0.6 5.1 2.7 1.2 3.0 17.2 4.7 6.6 50.4 5.7 4.0 9.3 24.3 5.5 3.5 32.0 7.4 5.1 8.5 8.1 5.2 0.4 1.4 1.3 1.1 0.7 12.1 24.5 26.0 21.1 0.3 3.3 21.5 4.9 9.8 12.4 2.4 2.0 11.0 16.2 153.3 0.4 2.4 1.3 9.0 5.1 56.0 18.7 4.3 4.5 29.2 9.8 11.4 3.8 14.9 8.0 0.1 15.0 0.6 5.4 65.9 2.2 0.3 1.4 68.9 13.0 0.7 10.9 0.0 1.7 1.5 2.7 4.9 11.9 6.8 0.8 65.4 9.8 7.7 7.9 0.2 11.5 4.9 4.9 30.1 16.7 78.6 4.4 18.0 23.5 40.2 21.6 23.0 22.6 12.8 16.3 19.9 22.5 13.6 20.9 23.1 63.2 25.9 29.2 25.7 13.3 38.3 6.8 6.3 6.1 7.5 7.0 5.3 7.3 6.6 7.8 6.6 9.3 8.5 1.7 9.6 13.4 2.0 22.2 1.5 2.2 1.8 4.0 0.7 2.0 1.7 3.1 0.0 1.1 0.0 2.1 0.3 44.0 0.1 1.9 3.9 3.0 2.0 1.7 2.7 0.0 10.3 6.7 2.0 0.5 2.9 0.0 1.0 25.3 4.2 3.6 0.0 14.7 0.0 13.4 0.1 0.0 35.2 6.0 2.8 1.2 23.1 3.6 29.0 19.3 2.5 29.9 1.0 1.1 11.3 0.0 1.5 8.2 4.1 0.2 3.8 3.3 1.3 6.6 2.0 4.7 1.5 3.4 2.9 1.1 0.3 37.1 1.5 0.2 2.1 PILRA FDF03 ENSG00000085514 "Paired immunoglobin like type 2 receptor alpha" Q9UKJ1 7 100367530-100400096 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 80.8;Kupffer cells: 100.7;Langerhans cells: 65.9;Leydig cells: 52.5;Macrophages: 144.7;monocytes: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1659.8;non-classical monocyte: 1146.1" "Group enriched" "Detected in all" 5 "granulocytes: 1659.8;monocytes: 1146.1" "Cell line enhanced" "Detected in some" "ASC diff: 27.9;HMC-1: 25.5;NB-4: 20.4" HPA056132 Approved "Secreted to blood" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056132: AB_2683048" "unprognostic (5.53e-2)" "prognostic favorable (2.99e-4)" "unprognostic (7.61e-2)" "unprognostic (2.88e-1)" "unprognostic (2.20e-1)" "unprognostic (5.88e-2)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (3.01e-3)" "unprognostic (9.95e-2)" "unprognostic (8.57e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.47e-2)" "unprognostic (3.17e-2)" "unprognostic (1.99e-1)" "unprognostic (4.80e-2)" 14.6 9.3 7.2 38.5 7.5 26.0 8.9 13.7 9.6 10.7 7.7 7.6 4.1 8.2 4.7 3.7 14.2 9.3 5.7 6.9 9.3 12.6 9.7 30.4 9.2 12.1 9.4 9.5 5.3 3.6 15.5 11.3 11.7 11.3 5.3 3.8 5.7 4.0 5.3 5.3 8.0 9.8 9.0 31.1 5.9 10.8 9.3 5.0 9.4 2.9 3.5 17.7 6.7 15.5 0.3 0.4 0.6 0.7 27.9 1.8 0.2 0.2 1.4 0.1 0.5 0.0 0.5 0.6 1.7 0.4 0.3 0.8 0.2 0.1 0.0 1.4 1.0 0.6 1.3 0.1 0.3 1.1 25.5 2.0 0.4 0.2 0.6 0.1 0.3 2.5 0.2 1.8 0.2 0.9 2.0 20.4 0.6 0.4 0.3 0.5 0.0 0.4 1.1 0.6 0.8 0.3 0.0 6.9 0.7 0.1 0.1 6.0 0.6 1.2 1.2 0.8 0.2 2.5 2.0 0.6 0.3 2.3 0.4 316.9 584.3 18.5 2.5 863.0 2.1 2.3 0.9 1.0 288.0 1.1 1.0 1.8 1659.8 6.4 1146.1 5.4 2.2 354.1 7.2 7.5 13.7 9.6 6.9 9.3 12.1 9.4 11.7 9.0 9.3 15.5 1.0 3.2 12.4 8.8 2.7 1.8 0.3 0.9 0.0 3.6 2.1 3.0 0.6 2.8 3.9 1.8 4.2 0.6 2.1 0.6 27.4 0.2 0.7 3.9 13.1 4.1 0.0 2.7 15.9 0.4 0.6 2.8 0.5 5.8 10.1 0.8 1.8 1.8 80.8 1.7 14.8 1.3 0.0 100.7 65.9 1.9 52.5 144.7 1.8 28.1 72.3 1.4 3.1 2.0 10.3 0.3 0.1 21.4 0.4 0.5 0.1 0.7 3.1 2.4 0.0 1.0 0.7 1.6 2.6 0.2 0.9 0.8 2.0 0.4 0.9 0.3 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "dendritic cells: 22.6;granulocytes: 26.6;Hofbauer cells: 30.3;Kupffer cells: 46.6;Macrophages: 41.7;Microglial cells: 39.4;monocytes: 20.9;NK-cells: 26.8;T-cells: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 78.6;HMC-1: 93.4;THP-1: 28.1;U-937: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 5.9 4.0 3.8 29.2 3.9 52.4 2.5 3.8 5.4 3.3 3.4 5.1 6.1 2.7 1.4 3.0 4.5 9.7 3.0 4.0 5.6 1.9 6.3 16.8 28.7 8.4 7.1 1.5 1.3 1.3 2.1 7.0 7.3 2.6 8.0 0.5 5.4 4.0 1.2 1.9 10.4 7.3 6.2 40.7 5.5 1.3 7.7 20.5 2.2 1.7 22.2 7.3 1.8 9.6 0.4 0.0 0.6 0.0 0.0 0.0 10.5 0.0 0.1 0.0 0.0 0.1 19.1 1.5 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 78.6 0.0 0.0 0.0 16.9 93.4 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.7 4.3 0.0 0.0 4.7 9.2 0.9 0.0 0.2 13.7 2.0 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.2 5.1 0.0 28.1 10.1 0.0 9.1 0.0 0.0 0.0 0.0 3.7 0.0 53.2 0.0 1.7 2.6 5.3 1.8 2.7 1.2 0.4 0.9 0.9 2.7 0.5 0.9 1.0 4.2 1.2 2.7 1.0 1.9 1.5 3.8 3.9 3.8 5.4 4.0 5.6 8.4 7.1 7.3 6.2 7.7 9.6 0.9 6.4 16.8 0.3 9.6 0.9 0.1 0.1 0.6 0.1 1.9 2.5 3.3 1.5 3.2 1.8 0.0 0.5 22.6 0.2 0.0 0.1 2.2 0.2 0.5 1.7 0.0 8.0 1.8 0.0 0.5 1.9 0.0 0.2 26.6 0.1 1.1 0.4 30.3 0.0 0.8 1.7 0.0 46.6 15.5 0.6 0.3 41.7 3.6 39.4 20.9 0.0 26.8 0.5 0.2 0.4 0.3 0.0 5.7 0.0 0.0 0.9 4.4 0.2 0.0 0.4 0.7 0.5 2.3 0.3 0.6 0.4 20.8 0.3 2.0 0.0 PLEKHO2 "DKFZp761K2312, PLEKHQ1, PP1628, pp9099" ENSG00000241839 "Pleckstrin homology domain containing O2" Q8TD55 15 64841883-64868002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 103.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 63.2;Kupffer cells: 52.3;Macrophages: 46.5;Muller glia cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 27.1;granulocytes: 77.3;monocytes: 73.0" "Cell line enhanced" "Detected in many" "ASC diff: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040055 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 200000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA040055: AB_10793954" "unprognostic (4.32e-2)" "unprognostic (7.32e-3)" "unprognostic (8.60e-2)" "unprognostic (9.10e-2)" "unprognostic (1.11e-1)" "unprognostic (2.90e-2)" "unprognostic (3.05e-2)" "unprognostic (2.80e-1)" "unprognostic (7.70e-2)" "unprognostic (2.05e-2)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.08e-3)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (1.78e-1)" "unprognostic (5.85e-3)" 37.9 31.8 23.1 30.5 26.9 52.0 22.7 25.0 25.0 17.0 16.7 23.6 10.0 19.8 5.7 13.9 22.4 26.0 16.5 21.7 24.4 14.2 11.8 42.2 34.3 31.8 26.2 14.9 8.2 7.4 10.3 25.4 26.6 17.4 7.8 14.4 9.9 13.9 5.8 10.6 17.8 22.9 27.6 103.2 16.3 8.3 28.0 16.0 29.9 8.2 21.1 25.8 16.7 25.5 6.5 4.2 7.9 7.8 68.0 38.8 18.4 18.5 27.4 19.2 19.6 5.1 4.0 17.1 9.5 37.7 19.5 2.2 9.0 7.4 11.2 26.6 2.7 17.2 1.9 6.0 52.2 19.4 24.7 28.3 6.5 24.0 7.8 16.6 27.0 3.5 5.2 59.5 25.9 1.9 4.1 20.9 15.0 3.2 3.7 14.9 19.0 12.2 3.1 4.4 0.6 6.7 7.7 2.6 25.4 12.9 2.7 26.1 35.3 14.8 13.4 14.1 7.8 22.0 37.1 5.8 16.0 24.8 8.8 22.2 43.2 25.6 13.2 52.3 11.9 9.8 7.4 12.2 27.1 6.8 3.1 6.5 77.3 7.0 73.0 3.1 10.7 36.0 23.1 26.9 25.0 25.0 21.7 24.4 31.8 26.2 26.6 27.6 28.0 25.5 24.9 0.0 5.6 17.3 9.1 5.6 2.3 2.3 0.6 0.6 6.4 8.3 3.6 2.8 2.4 9.2 0.0 4.2 15.9 0.5 3.9 2.4 5.0 1.4 5.9 26.1 0.0 2.1 0.2 1.5 5.9 8.6 0.5 2.3 18.4 2.5 34.2 2.1 63.2 0.0 0.2 0.3 4.1 52.3 24.3 2.9 18.3 46.5 14.2 8.4 18.9 56.8 16.5 2.5 2.7 2.0 0.0 25.6 2.7 3.5 0.0 2.2 2.1 3.8 13.1 10.2 5.9 0.9 2.3 1.9 4.4 6.0 10.5 4.6 0.4 3.4 PLXNC1 "CD232, VESPR" ENSG00000136040 "Plexin C1" O60486 12 94148577-94307675 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 57.0;Macrophages: 62.5;Melanocytes: 96.0;monocytes: 53.8" "Cancer enhanced" "Detected in all" "melanoma: 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.4" "Group enriched" "Detected in all" 4 "granulocytes: 16.4;monocytes: 8.6" "Cell line enhanced" "Detected in many" "HAP1: 33.3;Karpas-707: 25.8;SK-MEL-30: 41.4;U-266/70: 64.3;U-266/84: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066899 Approved Mitochondria NA NA 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA066899: AB_2685743" "unprognostic (1.49e-1)" "unprognostic (4.01e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (3.24e-2)" "unprognostic (4.67e-3)" "unprognostic (2.80e-2)" "unprognostic (3.49e-1)" "unprognostic (4.64e-2)" "unprognostic (1.78e-2)" "unprognostic (2.38e-1)" "unprognostic (4.02e-2)" "unprognostic (5.33e-3)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (5.48e-2)" 6.1 8.8 6.4 20.5 7.1 17.4 4.7 8.9 7.5 8.5 1.9 5.7 4.1 7.0 2.7 3.8 4.8 10.2 1.9 7.1 15.9 4.0 2.5 11.4 16.2 5.3 12.7 14.8 2.4 0.9 4.1 9.4 4.7 2.3 6.5 2.2 2.3 4.5 4.0 8.3 5.5 6.9 4.2 19.8 4.5 15.2 18.6 5.7 3.4 4.1 13.0 9.5 3.8 8.7 1.1 0.4 2.7 0.5 1.5 1.2 0.4 1.3 1.8 1.7 5.1 9.1 0.1 21.8 0.1 2.0 1.6 0.1 33.3 1.4 1.2 15.3 0.7 1.2 0.6 6.1 17.7 4.5 7.2 17.7 0.0 1.9 0.8 2.3 0.0 2.0 0.6 25.8 0.5 0.3 1.0 2.4 5.5 0.2 1.2 3.6 1.0 12.1 0.1 1.7 2.2 1.6 0.3 0.2 41.4 6.3 0.1 3.7 0.7 0.6 2.3 0.2 0.8 64.3 73.3 1.4 0.4 11.7 1.4 0.0 3.6 15.1 1.6 6.1 1.7 2.6 1.7 1.9 2.9 1.7 1.6 1.6 16.4 1.1 8.6 1.1 1.3 2.0 6.4 7.1 8.9 7.5 7.1 15.9 5.3 12.7 4.7 4.2 18.6 8.7 4.9 3.2 2.4 9.8 17.9 6.1 0.3 0.3 1.2 3.6 3.2 2.5 8.1 1.5 0.2 0.0 0.0 0.2 5.6 1.2 1.9 0.2 9.4 3.2 14.9 4.3 19.8 26.1 36.1 0.5 0.2 16.0 1.1 1.6 16.5 29.8 6.1 1.6 18.8 0.0 57.0 1.8 0.0 39.4 13.8 6.2 1.5 62.5 96.0 40.3 53.8 0.3 3.1 34.2 12.6 0.3 1.8 3.4 24.4 0.2 0.1 3.4 2.3 0.5 6.6 2.8 2.5 3.0 1.1 0.7 1.6 0.1 9.4 4.8 1.9 0.3 PPP1R18 "KIAA1949, phostensin" ENSG00000146112 "Protein phosphatase 1 regulatory subunit 18" Q6NYC8 6 30676389-30687895 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 208.4;Kupffer cells: 164.4;Langerhans cells: 179.3;monocytes: 212.8;NK-cells: 332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 215.8;neutrophil: 169.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 215.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044745, HPA051000" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 11000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Nucleoplasm "HPA044745: AB_2679070, HPA051000: AB_2681304" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.71e-4)" "unprognostic (1.01e-1)" "unprognostic (2.11e-2)" "unprognostic (1.59e-2)" "unprognostic (2.90e-2)" "unprognostic (3.37e-2)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (3.61e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (9.33e-2)" "unprognostic (4.76e-2)" 35.4 16.7 9.5 42.5 9.1 56.0 25.9 9.9 12.8 30.2 7.0 38.0 8.8 36.8 3.5 18.1 28.6 25.6 23.2 9.4 12.1 14.2 16.8 51.5 75.5 17.8 12.6 26.8 10.1 2.7 7.0 21.4 15.5 19.7 7.7 2.6 15.4 11.5 10.8 21.6 33.7 17.3 13.7 80.4 19.5 5.9 15.6 53.5 17.6 9.0 38.2 36.1 24.4 13.9 63.2 9.4 34.4 37.3 28.0 80.4 1.7 48.4 63.6 43.3 29.9 6.6 11.2 64.7 25.0 77.3 73.7 35.8 21.6 44.7 29.6 74.8 2.2 79.3 20.7 6.6 59.1 28.6 116.3 44.0 44.0 97.9 89.8 64.5 60.0 53.3 27.2 58.2 57.8 6.9 40.8 43.5 3.2 1.6 13.8 162.8 28.8 33.9 18.0 3.4 3.8 19.2 30.1 10.9 65.9 18.8 9.4 26.8 90.8 139.4 29.2 29.4 103.3 11.6 57.3 77.3 40.7 131.9 155.9 43.0 16.4 215.8 43.4 21.8 31.8 20.9 23.1 42.5 9.5 22.0 16.7 32.5 169.6 37.8 25.2 14.9 39.7 22.6 9.5 9.1 9.9 12.8 9.4 12.1 17.8 12.6 15.5 13.7 15.6 13.9 39.1 3.2 15.7 1.6 89.7 109.0 29.6 15.7 79.6 2.3 14.2 14.6 3.1 8.6 4.6 9.2 0.0 3.1 116.5 0.8 0.0 25.1 24.2 4.4 24.4 67.8 1.8 35.4 0.8 8.2 20.4 34.1 7.1 6.7 53.2 5.9 32.9 8.2 208.4 3.3 1.3 0.8 8.2 164.4 179.3 19.9 27.7 123.3 39.2 19.7 212.8 1.0 332.7 11.1 0.1 20.8 0.0 23.3 52.9 23.8 0.4 2.5 4.4 3.1 26.3 28.6 53.5 1.2 1.3 38.3 59.7 4.0 141.6 6.8 0.7 22.5 PPP6R1 "KIAA1115, SAP190, SAPS1" ENSG00000105063 "Protein phosphatase 6 regulatory subunit 1" Q9UPN7 19 55229779-55259017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 28.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043989, HPA063681" Approved Enhanced Cytosol No No 19000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA043989: AB_10987309, HPA063681: AB_2685087" "unprognostic (1.15e-1)" "unprognostic (2.34e-1)" "unprognostic (1.20e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.82e-6)" "unprognostic (2.22e-2)" "unprognostic (5.44e-2)" "unprognostic (5.41e-2)" "unprognostic (3.35e-3)" "unprognostic (1.63e-3)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" "unprognostic (3.65e-2)" "unprognostic (3.30e-2)" "unprognostic (2.20e-1)" 21.8 36.8 31.6 52.7 35.4 96.4 20.3 8.0 35.7 22.0 19.4 28.3 38.1 25.7 5.1 35.2 26.6 23.8 28.3 41.7 12.8 23.8 25.5 28.3 82.4 15.0 13.2 21.1 20.3 22.6 29.7 21.2 15.6 23.5 12.2 8.8 24.1 21.4 38.7 28.5 42.4 18.4 8.3 61.5 42.6 89.7 20.6 62.2 27.3 20.2 49.3 33.4 23.4 18.1 101.2 143.4 28.7 46.1 33.5 30.8 73.1 63.1 54.7 64.8 55.2 95.4 67.9 261.0 33.7 56.6 48.2 48.2 10.3 65.9 25.1 98.2 241.8 198.5 71.8 71.0 57.5 295.9 187.6 45.4 37.4 64.5 43.4 34.7 42.2 178.7 105.5 112.1 42.5 64.5 218.1 105.5 39.3 82.2 116.5 131.8 56.4 216.0 45.9 126.6 81.8 45.5 58.7 69.7 62.2 24.6 38.3 219.7 55.3 101.3 49.7 39.4 96.4 55.4 108.7 184.1 92.4 240.5 79.1 0.0 2.8 6.5 11.7 3.9 6.6 3.3 4.8 9.3 4.0 2.7 4.9 7.5 3.1 7.8 3.4 28.6 3.6 6.8 31.6 35.4 8.0 35.7 41.7 12.8 15.0 13.2 15.6 8.3 20.6 18.1 14.7 12.8 19.8 11.1 27.2 2.8 8.9 1.0 11.4 16.3 14.2 10.4 2.6 18.6 6.2 18.4 10.4 11.1 66.2 21.7 0.0 21.2 237.3 36.3 13.6 15.8 15.1 41.4 14.4 28.7 9.3 9.7 50.4 19.7 7.6 19.7 16.1 22.3 32.4 30.3 10.6 15.7 2.0 31.2 4.8 55.3 18.6 34.0 0.0 9.4 21.9 14.7 51.5 6.0 11.3 47.3 18.8 19.5 27.0 22.1 34.2 12.3 12.6 15.3 19.7 12.5 10.7 38.5 41.0 13.9 3.4 11.4 39.6 31.3 14.2 50.7 PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in some" "dendritic cells: 542.1;NK-cells: 1231.7;T-cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8" "Group enriched" "Detected in all" 50 "NK-cells: 656.8;T-cells: 900.4" "Cell line enriched" "Detected in some" 11 "HDLM-2: 240.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" NA NA 2100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" 5.0 2.0 0.7 7.6 0.7 28.6 2.7 0.7 1.3 1.3 1.3 2.2 2.3 3.5 1.1 1.9 1.9 4.2 2.2 0.6 0.6 1.7 6.3 16.5 20.3 1.4 0.7 1.0 1.0 0.5 0.9 2.7 1.0 1.5 1.4 0.0 2.3 1.2 2.6 0.9 5.2 2.0 1.3 49.4 4.7 0.6 1.0 5.8 2.6 1.5 4.9 3.8 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 240.1 0.0 1.4 0.0 7.4 0.0 0.3 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 5.2 1.9 0.9 900.4 1.7 628.8 4.0 125.8 499.1 2.0 3.5 52.1 313.0 15.4 656.8 2.6 2.9 108.8 587.5 0.7 0.7 0.7 1.3 0.6 0.6 1.4 0.7 1.0 1.3 1.0 1.0 3.1 3.2 13.6 0.0 4.4 0.4 0.1 0.0 0.6 0.0 0.5 0.5 0.8 1.5 2.5 0.0 0.0 0.2 542.1 0.1 0.0 0.3 0.0 0.2 0.3 1.9 0.0 19.0 0.0 0.0 0.1 2.1 7.7 0.4 8.8 0.0 10.8 2.7 0.1 0.0 0.0 0.0 0.0 7.8 2.3 0.0 0.0 5.7 0.0 1.9 7.4 0.0 1231.7 0.0 0.1 0.0 0.0 0.0 88.5 0.1 0.1 1.6 1.5 0.0 0.0 1.1 0.8 0.0 0.0 0.5 0.9 0.7 265.4 0.0 0.1 0.0 PRPF38B "FLJ10330, NET1" ENSG00000134186 "Pre-mRNA processing factor 38B" Q5VTL8 1 108692310-108702928 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053255 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" "HPA053255: AB_2682093" "unprognostic (2.13e-3)" "unprognostic (9.66e-2)" "unprognostic (9.67e-2)" "unprognostic (4.57e-2)" "unprognostic (5.00e-3)" "unprognostic (1.09e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (3.28e-3)" "unprognostic (3.77e-3)" "unprognostic (9.49e-3)" "unprognostic (1.34e-1)" "unprognostic (9.44e-3)" "prognostic unfavorable (2.03e-4)" "unprognostic (6.97e-2)" "unprognostic (1.64e-1)" "unprognostic (1.42e-1)" "unprognostic (2.26e-1)" 24.4 21.5 19.6 35.3 20.9 63.0 24.1 31.8 23.2 23.0 18.5 25.6 24.3 23.2 15.7 24.4 22.3 18.8 18.6 19.2 22.8 24.5 25.0 26.1 45.5 22.9 20.4 23.7 31.0 16.5 22.4 24.0 22.2 23.3 21.4 24.9 25.9 14.8 25.6 23.2 34.6 15.3 19.5 43.1 24.5 14.7 21.4 37.5 25.9 16.0 31.1 23.1 22.7 23.1 57.5 22.5 52.0 33.8 29.2 23.3 47.8 59.3 22.7 27.7 29.6 43.4 26.7 77.4 31.4 18.8 19.1 52.2 48.5 30.9 40.7 45.2 51.0 60.4 83.7 41.0 28.7 83.4 49.5 16.1 42.5 28.6 56.2 37.3 23.2 35.9 75.0 56.6 29.4 42.7 61.6 67.4 56.8 26.1 40.4 61.6 99.3 32.8 26.7 47.0 49.4 35.5 40.8 47.3 58.1 32.2 24.1 53.6 38.8 54.0 41.0 43.9 51.2 52.6 35.4 71.0 47.5 61.9 57.7 24.3 19.8 27.1 23.9 19.5 24.8 19.6 21.8 19.3 23.3 23.9 19.9 20.2 30.0 31.9 17.7 27.5 24.6 13.5 19.6 20.9 31.8 23.2 19.2 22.8 22.9 20.4 22.2 19.5 21.4 23.1 81.7 105.8 143.8 38.5 166.5 246.8 199.4 79.9 90.0 96.1 87.6 69.0 60.7 105.8 120.5 60.7 135.5 86.3 227.0 88.7 13.7 79.5 34.3 62.1 117.2 101.4 95.0 88.1 27.7 66.2 104.1 85.5 61.2 96.4 103.1 72.5 88.5 59.8 78.3 37.0 30.1 110.7 61.1 127.8 203.1 19.3 99.1 131.0 104.9 63.7 138.1 50.7 242.0 39.7 65.0 75.7 81.2 85.0 139.3 172.6 81.3 17.3 73.9 74.3 46.0 89.5 108.1 96.1 62.3 102.6 265.0 87.7 222.3 98.4 131.7 234.7 RASGRP2 CALDAG-GEFI ENSG00000068831 "RAS guanyl releasing protein 2" Q7LDG7 11 64726911-64745456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 147.3;lymphoid tissue: 140.5" "Cell type enhanced" "Detected in many" "B-cells: 125.5;dendritic cells: 86.1;Kupffer cells: 77.3;Macrophages: 72.2;NK-cells: 98.9;Sertoli cells: 131.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 103.4;HL-60: 192.8;NB-4: 347.1;REH: 105.0;THP-1: 108.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015635, HPA015667" Approved Supported "Plasma membrane" NA NA 1900000 "Cluster 37: B-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA015635: , HPA015667: AB_1856090" "unprognostic (5.96e-2)" "unprognostic (3.24e-3)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (3.52e-2)" "unprognostic (4.74e-5)" "unprognostic (1.11e-2)" "unprognostic (7.36e-3)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.91e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" 23.8 10.1 16.1 52.9 35.5 147.3 16.8 9.6 22.4 20.1 7.1 37.5 6.6 28.3 4.6 9.1 29.2 8.7 51.7 13.4 13.4 15.8 10.1 29.5 106.0 12.4 16.3 9.1 4.1 1.0 5.5 10.9 11.9 23.2 5.3 1.3 4.6 18.6 12.2 6.1 86.4 15.0 9.5 140.5 17.5 11.9 20.7 34.6 10.6 10.2 62.0 26.7 15.5 9.8 0.1 0.1 3.0 0.1 0.0 0.3 8.7 1.3 0.2 1.2 0.8 1.5 0.2 62.8 2.7 0.2 0.8 0.7 5.4 0.9 0.3 0.3 1.7 103.4 0.0 0.4 0.3 192.8 35.9 0.0 0.0 0.5 0.0 0.0 0.1 25.9 4.1 1.1 0.0 1.4 45.4 347.1 2.5 0.4 0.0 105.0 0.2 4.4 0.0 0.0 0.5 2.3 0.1 0.1 0.0 2.2 0.6 108.5 0.6 0.0 2.0 1.5 0.1 0.5 0.1 58.9 0.0 58.2 0.0 64.4 34.1 59.9 70.4 88.0 37.3 170.7 72.9 57.2 34.5 100.2 92.7 83.1 70.9 55.3 105.8 85.9 93.8 67.5 16.1 35.5 9.6 22.4 13.4 13.4 12.4 16.3 11.9 9.5 20.7 9.8 27.4 3.2 1.8 2.6 125.5 2.3 0.1 0.0 0.0 2.6 1.6 3.7 53.1 2.8 0.0 0.0 0.0 1.7 86.1 0.1 0.0 0.0 6.6 1.9 27.1 13.5 0.0 24.2 6.0 0.0 1.3 6.6 2.6 1.2 3.8 5.7 31.4 1.7 6.1 0.0 12.2 0.1 0.0 77.3 19.7 19.5 18.0 72.2 0.0 6.5 55.8 0.7 98.9 2.5 0.9 0.0 0.0 47.8 28.6 0.1 0.4 0.9 0.7 2.5 131.5 5.4 56.8 18.0 43.9 0.9 1.3 11.8 61.0 0.8 0.3 0.2 RELB REL-B ENSG00000104856 "RELB proto-oncogene, NF-kB subunit" Q01201 19 45001449-45038198 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 108.5;monocytes: 112.5;Plasma cells: 108.8;Prostatic glandular cells: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 61.9;HDLM-2: 79.5;U-698: 67.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB007753, HPA040506" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB007753: AB_562340, HPA040506: AB_2677011" "prognostic favorable (1.55e-4)" "unprognostic (1.20e-1)" "unprognostic (7.13e-2)" "unprognostic (5.52e-2)" "unprognostic (1.12e-2)" "unprognostic (3.41e-2)" "unprognostic (1.71e-2)" "unprognostic (4.30e-2)" "unprognostic (5.81e-3)" "unprognostic (1.02e-3)" "unprognostic (6.01e-2)" "unprognostic (6.48e-2)" "prognostic unfavorable (2.99e-6)" "unprognostic (2.68e-2)" "unprognostic (4.69e-2)" "unprognostic (2.09e-1)" "unprognostic (2.20e-2)" 17.2 13.1 3.5 18.7 2.9 40.1 12.6 2.9 4.4 9.1 3.1 13.3 10.8 14.1 0.8 8.7 9.2 7.4 12.7 3.1 3.4 21.3 13.0 23.0 19.2 4.9 3.5 6.4 16.5 2.1 4.0 4.8 4.1 15.3 3.9 0.2 12.1 5.2 14.0 16.5 17.7 4.9 3.6 29.1 12.0 4.3 4.6 9.2 10.0 1.4 15.6 13.8 8.1 4.1 22.2 13.0 1.3 5.7 2.8 9.1 4.5 3.9 27.5 5.9 9.6 4.5 23.6 61.9 11.0 6.4 20.8 9.8 0.5 9.0 5.1 79.5 2.0 2.2 0.8 2.5 23.8 4.9 35.3 15.0 3.7 12.3 14.4 5.4 3.9 1.7 0.5 39.2 2.1 5.3 1.1 14.9 2.0 6.3 2.4 4.8 3.2 7.7 10.0 33.7 0.1 2.0 4.1 11.4 11.6 1.4 4.0 11.8 12.6 14.4 7.1 5.3 14.4 49.0 31.2 67.0 15.6 1.7 8.1 0.0 5.1 2.5 1.4 3.4 2.0 9.2 2.2 1.9 3.8 8.0 1.7 0.8 15.2 2.1 2.8 4.1 1.1 2.0 3.5 2.9 2.9 4.4 3.1 3.4 4.9 3.5 4.1 3.6 4.6 4.1 16.4 6.4 12.4 2.3 64.4 37.9 108.5 20.3 40.9 0.0 17.6 11.3 1.8 24.3 15.7 3.7 0.0 4.2 35.0 53.0 9.8 33.1 5.2 15.1 15.2 30.8 22.8 22.5 3.0 31.5 7.3 35.4 65.2 29.1 50.9 3.8 5.0 3.5 18.4 3.3 1.7 33.3 8.2 15.1 74.9 3.4 4.7 44.7 24.9 3.7 112.5 0.8 7.2 1.5 2.5 37.4 90.3 2.6 108.8 145.3 48.0 19.4 7.4 0.3 6.6 28.9 27.3 1.1 1.7 27.7 31.8 9.9 53.8 4.1 16.8 89.7 RGS18 RGS13 ENSG00000150681 "Regulator of G protein signaling 18" Q9NS28 1 192158462-192185815 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.2;lymphoid tissue: 25.4" "Cell type enriched" "Detected in some" 4 "Macrophages: 527.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 353.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 353.1" "Group enriched" "Detected in some" 5 "HEL: 60.2;HL-60: 46.7;NB-4: 43.6;U-937: 39.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028727, HPA045780" Uncertain Approved "Golgi apparatus" NA NA 340000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "HPA028727: AB_2797219, HPA045780: AB_10962728" "unprognostic (3.09e-2)" "unprognostic (4.32e-2)" "unprognostic (8.66e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.48e-1)" "unprognostic (2.18e-2)" "unprognostic (2.58e-1)" "unprognostic (1.87e-1)" "unprognostic (3.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.30e-3)" "unprognostic (8.21e-3)" "unprognostic (2.81e-4)" "unprognostic (1.73e-2)" "unprognostic (9.91e-2)" 4.3 2.3 0.7 14.1 0.6 13.2 2.3 0.9 0.7 2.4 0.9 2.4 2.9 1.0 0.5 1.9 1.3 5.3 0.8 0.6 1.2 1.0 5.3 4.1 8.4 1.5 1.0 0.8 0.8 0.4 0.3 2.2 1.5 1.1 2.9 0.6 0.7 1.0 0.9 0.4 5.8 2.9 1.3 25.4 1.9 0.4 0.8 4.2 0.8 3.1 4.4 4.8 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.2 0.0 0.0 0.0 46.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 2.7 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 39.9 0.0 195.5 50.7 353.1 0.8 66.7 6.8 0.1 0.8 1.3 51.0 0.2 0.1 0.2 164.8 0.6 82.1 12.0 0.0 94.4 0.7 0.6 0.9 0.7 0.6 1.2 1.5 1.0 1.5 1.3 0.8 1.6 0.3 6.4 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.0 1.8 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 16.0 0.0 0.0 0.0 0.8 0.0 0.0 24.7 0.0 5.7 1.1 7.3 0.0 0.0 0.0 0.0 124.9 27.3 0.8 0.3 527.4 0.0 15.9 128.3 0.1 28.8 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.3 1.5 0.3 13.1 0.3 0.1 0.1 0.2 0.1 0.1 0.1 7.6 0.0 0.1 0.0 RGS19 "GAIP, RGSGAIP" ENSG00000171700 "Regulator of G protein signaling 19" P49795 20 64073181-64079988 "Predicted intracellular proteins" Autophagy "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.2;lymphoid tissue: 77.5" "Cell type enhanced" "Detected in many" "B-cells: 97.8;dendritic cells: 82.0;Hofbauer cells: 135.0;Kupffer cells: 104.6;Macrophages: 101.6;monocytes: 86.3;NK-cells: 140.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 154.2;NB-4: 128.1;THP-1: 107.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056384, HPA069984" Enhanced Supported "Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Cell Junctions" "Nucleoli fibrillar center" "HPA056384: AB_2732602, HPA069984: AB_2732145" "unprognostic (3.98e-2)" "unprognostic (2.32e-1)" "unprognostic (4.26e-3)" "unprognostic (8.42e-2)" "unprognostic (2.03e-1)" "unprognostic (9.94e-2)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.25e-2)" "unprognostic (2.41e-2)" "unprognostic (3.91e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "prognostic unfavorable (2.06e-9)" "unprognostic (1.35e-1)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (4.66e-3)" 12.5 8.8 7.1 28.5 6.8 57.2 9.0 7.3 7.8 5.9 6.3 6.7 7.5 5.1 2.0 8.1 6.9 6.0 6.4 6.7 7.3 7.6 5.9 19.6 35.2 12.3 8.8 2.3 7.0 2.7 4.3 7.2 10.0 7.3 2.2 0.3 8.5 2.5 2.5 8.4 21.1 4.3 11.4 77.5 8.2 1.8 11.8 13.9 6.8 2.2 17.3 8.3 6.9 12.2 16.1 24.1 6.8 12.2 3.0 4.9 11.5 10.0 6.9 20.2 8.4 36.0 21.8 28.1 27.0 6.2 21.6 15.4 7.0 12.8 4.8 14.0 13.2 40.3 12.3 14.8 4.0 83.0 154.2 3.3 7.7 8.6 3.0 4.0 13.3 18.4 15.5 14.5 6.2 28.6 61.6 128.1 7.0 13.8 30.3 51.1 4.0 20.4 5.7 7.8 12.9 12.1 10.3 6.3 13.6 3.4 8.3 107.3 14.0 18.9 9.5 3.3 9.8 9.1 7.6 34.7 10.5 62.6 12.8 289.5 273.2 760.9 96.6 396.0 99.2 125.7 91.1 92.6 228.8 125.7 62.4 64.9 606.5 75.1 458.3 130.8 107.1 204.7 7.1 6.8 7.3 7.8 6.7 7.3 12.3 8.8 10.0 11.4 11.8 12.2 19.0 3.2 4.1 2.0 97.8 9.7 6.4 8.0 4.0 0.1 10.4 13.3 3.9 2.8 5.7 1.8 0.0 3.0 82.0 0.5 0.0 12.0 0.5 2.8 8.3 17.2 0.0 14.7 1.4 14.3 8.1 6.5 4.6 2.2 48.8 4.5 15.0 0.8 135.0 0.0 1.0 0.5 4.1 104.6 50.0 1.1 4.4 101.6 5.4 17.8 86.3 0.3 140.1 2.5 0.2 16.9 3.8 1.2 25.0 14.5 0.1 2.4 3.3 0.2 13.1 2.4 8.8 0.3 7.0 5.2 8.9 1.8 57.1 3.7 0.9 8.8 RHOF "ARHF, FLJ20247, RIF" ENSG00000139725 "Ras homolog family member F, filopodia associated" Q9HBH0 12 121777754-121803403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 273.9;Langerhans cells: 224.9;monocytes: 241.2;Pancreatic endocrine cells: 191.7;Paneth cells: 279.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 129.0;HDLM-2: 177.1;PC-3: 147.3;RPTEC TERT1: 127.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045912, HPA076019" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA045912: , HPA076019: AB_2732299" "unprognostic (1.26e-1)" "unprognostic (8.73e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-5)" "unprognostic (1.38e-3)" "unprognostic (2.37e-4)" "unprognostic (1.34e-1)" "unprognostic (5.51e-2)" "unprognostic (1.10e-4)" "unprognostic (1.10e-1)" "unprognostic (5.01e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-2)" "unprognostic (7.51e-4)" "unprognostic (1.14e-1)" 6.5 13.3 11.5 26.6 9.9 47.4 5.5 21.6 12.0 14.3 10.6 24.3 31.8 13.2 21.8 11.7 10.0 9.8 15.0 10.4 11.0 16.2 3.9 20.6 41.0 13.0 12.2 8.9 6.1 7.7 5.1 5.7 13.4 9.2 19.3 9.9 11.5 9.8 11.8 9.2 32.3 11.5 8.7 33.3 28.2 9.0 10.6 25.6 14.6 2.8 31.4 9.1 7.3 11.7 58.3 69.2 12.4 15.3 4.4 6.4 5.6 5.3 5.2 2.5 4.4 28.8 129.0 6.3 42.6 6.0 1.4 8.6 23.2 33.7 2.2 177.1 8.0 37.9 47.5 27.7 10.1 38.6 25.8 9.0 7.5 5.4 2.9 23.8 17.6 44.7 5.6 9.9 1.4 41.7 50.7 56.7 10.4 13.6 147.3 26.5 0.7 10.8 127.9 4.9 9.9 9.4 38.5 4.5 2.6 5.6 19.9 15.0 21.4 4.0 40.1 12.5 1.5 12.3 7.6 20.0 5.0 42.9 2.6 23.8 10.9 41.5 97.0 36.5 92.7 55.5 77.2 82.5 31.0 45.2 59.5 73.2 24.4 61.4 69.8 74.3 90.2 43.3 11.5 9.9 21.6 12.0 10.4 11.0 13.0 12.2 13.4 8.7 10.6 11.7 3.1 38.5 10.7 1.0 54.1 8.7 1.9 5.5 3.4 8.1 9.3 3.8 1.5 15.7 11.3 23.9 0.0 2.7 111.8 273.9 41.1 34.0 20.2 16.5 5.6 3.5 6.7 12.2 5.3 55.3 3.9 5.3 50.4 37.1 20.8 13.1 10.0 4.0 14.4 0.0 3.9 28.6 2.0 10.9 224.9 53.8 4.1 40.3 21.4 3.7 241.2 4.7 103.0 1.0 1.2 191.7 279.6 2.2 39.4 3.8 121.6 15.1 13.5 9.7 6.6 2.6 4.5 17.7 2.9 2.5 13.2 5.5 99.2 23.4 17.3 44.3 RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.2;lymphoid tissue: 101.6" "Cell type enhanced" "Detected in all" "dendritic cells: 132.3;NK-cells: 111.2;T-cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: AB_10796682" "unprognostic (3.01e-2)" "unprognostic (6.98e-3)" "unprognostic (3.96e-2)" "unprognostic (5.36e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (6.52e-2)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (2.38e-2)" "prognostic favorable (1.04e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.54e-1)" "unprognostic (3.91e-2)" "unprognostic (1.28e-1)" "unprognostic (2.69e-2)" 22.7 18.4 16.1 28.8 16.2 91.2 16.0 14.4 24.5 18.3 13.9 18.3 14.1 16.6 3.2 11.8 20.0 14.0 21.3 15.5 15.0 20.7 23.4 48.3 40.4 19.4 16.8 17.8 19.5 5.4 17.6 8.2 17.6 19.7 4.9 3.4 14.8 5.8 21.3 11.8 37.2 6.3 16.9 101.6 17.8 12.8 20.9 18.0 18.8 8.2 21.1 18.1 14.4 20.0 10.3 15.9 12.5 18.4 5.8 5.0 23.3 10.3 6.5 11.8 5.3 11.1 6.4 12.4 13.0 6.0 6.8 11.1 7.2 6.8 4.7 6.4 21.7 16.7 12.4 18.7 15.9 16.7 20.4 6.0 6.4 9.4 8.2 6.9 12.4 20.6 28.6 8.8 5.0 20.3 38.9 108.0 20.3 4.4 21.5 36.3 7.8 32.2 5.3 4.5 11.8 12.3 23.9 4.8 12.1 5.9 13.4 53.3 18.6 8.7 13.4 13.5 12.5 19.9 13.5 31.6 7.8 62.8 12.4 7.0 25.6 61.3 31.6 19.1 27.7 4.2 19.3 27.6 23.8 3.9 15.7 22.9 40.4 11.3 22.7 14.8 21.8 21.6 16.1 16.2 14.4 24.5 15.5 15.0 19.4 16.8 17.6 16.9 20.9 20.0 15.2 9.6 3.6 7.8 23.5 4.8 4.6 2.4 6.2 10.1 6.0 7.1 2.8 4.3 3.1 7.3 6.2 8.8 132.3 2.3 9.8 6.5 1.4 5.2 7.4 11.0 4.9 13.7 6.5 9.2 9.6 8.8 8.2 4.9 21.0 12.3 8.6 4.8 38.8 8.4 4.8 3.1 2.0 46.7 32.4 2.5 9.3 52.4 10.6 15.0 41.5 11.7 111.2 3.5 4.5 5.5 1.0 7.9 55.1 4.5 1.8 7.0 4.7 9.6 6.6 8.9 10.0 9.1 9.9 4.8 5.8 3.7 73.1 12.2 3.7 1.9 RNF44 KIAA1100 ENSG00000146083 "Ring finger protein 44" Q7L0R7 5 176526712-176538025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 105.1;Late spermatids: 398.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038981 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA038981: AB_10674846" "unprognostic (1.85e-1)" "unprognostic (3.07e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (2.57e-7)" "unprognostic (1.50e-1)" "unprognostic (2.56e-2)" "prognostic unfavorable (8.45e-4)" "unprognostic (1.61e-1)" "unprognostic (4.54e-2)" "unprognostic (5.36e-2)" "unprognostic (5.78e-2)" "unprognostic (1.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-3)" "unprognostic (1.62e-1)" "unprognostic (5.12e-3)" "unprognostic (1.15e-2)" 16.7 17.8 15.9 28.9 14.0 42.7 18.1 8.6 19.3 18.3 6.1 26.3 20.2 16.3 5.4 25.9 19.1 9.1 17.0 14.2 14.4 21.7 14.6 22.0 37.7 12.5 12.0 24.9 19.5 10.3 15.7 13.1 9.9 19.5 12.6 8.4 23.2 9.3 11.8 30.5 34.6 7.8 8.5 54.7 20.4 20.2 15.0 30.9 25.1 7.5 24.2 18.0 21.1 11.4 9.3 20.9 32.7 30.6 6.4 5.3 87.6 5.3 4.6 3.5 4.5 31.9 20.2 17.7 32.0 3.0 16.0 24.8 14.8 31.8 4.0 69.0 26.1 18.9 20.1 29.8 8.1 22.1 25.0 10.3 25.1 3.9 11.7 11.4 9.8 33.8 21.4 25.9 4.8 32.1 51.6 49.3 43.4 12.1 25.5 21.0 8.6 25.8 12.0 21.4 40.1 48.8 8.0 21.7 31.2 21.5 24.0 43.9 16.0 8.8 13.1 7.1 10.0 32.6 26.3 24.1 4.3 44.7 11.7 0.0 1.5 2.9 3.0 1.8 2.2 1.9 2.3 2.5 1.0 2.3 2.2 2.7 5.3 2.1 1.6 1.1 3.1 1.8 15.9 14.0 8.6 19.3 14.2 14.4 12.5 12.0 9.9 8.5 15.0 11.4 18.3 12.8 28.6 22.9 39.0 40.3 10.5 24.4 43.3 17.1 30.7 25.4 13.3 20.0 18.2 12.9 10.4 10.5 46.6 41.7 7.9 12.3 105.1 15.3 13.7 19.9 40.7 10.1 20.5 16.2 11.7 11.1 21.4 20.2 15.8 13.7 15.7 10.5 15.3 28.6 24.7 40.7 18.3 56.5 19.6 398.5 19.9 26.8 5.4 21.5 38.4 9.2 40.2 13.0 12.2 21.2 24.3 12.4 17.0 22.2 27.1 10.8 13.9 8.5 6.6 14.1 13.0 3.6 12.0 35.0 49.6 12.0 40.3 12.9 35.7 15.3 RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "dendritic cells: 336.4;Langerhans cells: 133.9;NK-cells: 251.3;Plasma cells: 87.1;T-cells: 215.4" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 124.9;Karpas-707: 155.6;SK-MEL-30: 92.4;U-266/70: 54.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" 3.5 1.4 3.7 21.1 3.6 68.8 3.5 3.8 4.6 19.7 3.7 3.7 5.0 1.6 0.7 2.6 1.6 5.3 1.1 3.6 3.8 1.6 3.7 9.5 34.7 4.7 4.4 0.6 0.9 0.4 0.7 0.9 4.3 1.9 4.2 0.1 4.7 0.8 3.8 11.5 15.0 1.6 4.1 35.1 5.5 2.3 4.3 11.2 1.8 0.7 29.0 6.5 1.5 4.5 0.3 10.4 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.5 0.0 0.5 0.0 19.3 18.4 16.4 0.1 0.4 11.1 0.0 0.7 124.9 1.9 0.4 1.8 0.1 0.0 4.5 42.8 0.1 0.0 0.0 1.1 0.0 0.0 3.1 0.1 155.6 0.0 0.0 1.5 37.9 0.7 0.0 3.2 0.0 0.1 22.7 0.0 0.5 3.5 0.0 7.3 0.1 92.4 2.9 0.0 25.7 0.0 0.0 1.9 0.0 0.5 54.6 40.4 18.2 0.1 42.0 4.4 0.7 1.1 7.0 21.7 4.5 11.3 6.7 7.9 18.7 1.4 5.7 3.9 14.6 1.3 28.7 7.7 1.5 9.2 5.5 3.7 3.6 3.8 4.6 3.6 3.8 4.7 4.4 4.3 4.1 4.3 4.5 4.4 0.0 3.6 0.0 57.7 7.6 0.8 4.6 2.2 0.0 9.8 11.3 2.4 0.0 1.5 1.8 0.0 0.1 336.4 0.5 0.0 0.2 2.3 1.1 1.2 2.4 0.0 13.7 0.0 0.2 0.1 3.3 13.3 2.3 45.2 0.0 2.2 1.5 4.6 0.0 0.0 0.5 0.0 22.9 133.9 1.0 0.0 55.6 46.2 1.0 51.1 0.0 251.3 0.0 0.1 0.1 0.1 0.7 87.1 1.2 0.0 0.3 0.5 0.0 0.0 3.5 3.6 0.3 4.1 2.3 5.8 0.3 215.4 0.1 0.4 0.4 S100Z "Gm625, S100-zeta" ENSG00000171643 "S100 calcium binding protein Z" Q8WXG8 5 76850001-76921650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.4;lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 7.4;Kupffer cells: 8.7;Macrophages: 11.8;Microglial cells: 32.8;monocytes: 26.1" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "classical monocyte: 35.0;eosinophil: 31.8;intermediate monocyte: 34.0;myeloid DC: 19.5;neutrophil: 11.8;non-classical monocyte: 39.6" "Group enriched" "Detected in many" 6 "dendritic cells: 19.5;granulocytes: 31.8;monocytes: 39.6" "Cell line enriched" "Detected in some" 6 "U-698: 81.9" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.3" "Low region specificity" "Detected in all" HPA051929 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Centrosome, Cytosol" Nucleoplasm "HPA051929: AB_2732571" "unprognostic (4.17e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.61e-4)" "unprognostic (1.86e-1)" "unprognostic (4.62e-2)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "unprognostic (8.89e-2)" "unprognostic (2.17e-1)" "unprognostic (3.54e-3)" "unprognostic (1.32e-1)" "unprognostic (9.47e-5)" "unprognostic (3.39e-4)" "unprognostic (8.94e-2)" "unprognostic (6.85e-2)" "unprognostic (1.62e-1)" 0.3 0.2 1.1 2.0 0.6 2.4 0.2 0.4 1.1 0.0 0.1 0.3 0.4 0.1 0.1 0.3 0.1 0.7 0.1 0.5 0.5 0.1 0.3 0.7 0.9 0.6 0.6 0.0 0.9 0.1 0.1 1.2 0.6 0.2 0.4 0.0 0.2 0.1 0.2 0.0 0.8 0.6 0.5 3.2 0.4 0.2 1.0 0.8 0.1 0.0 2.5 0.5 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 2.7 0.1 0.2 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.1 1.0 0.1 81.9 3.3 0.0 0.0 2.5 35.0 31.8 0.8 34.0 0.2 4.7 0.5 0.1 19.5 2.1 0.0 0.0 11.8 0.7 39.6 0.1 0.7 10.5 1.1 0.6 0.4 1.1 0.5 0.5 0.6 0.6 0.6 0.5 1.0 1.1 0.2 0.0 0.0 0.3 2.7 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 2.1 2.1 0.0 0.2 0.2 0.5 0.2 0.0 0.5 0.4 0.0 7.4 0.0 2.0 0.0 0.0 8.7 1.1 0.0 0.0 11.8 3.6 32.8 26.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.1 1.4 0.0 0.0 0.0 S1PR4 EDG6 ENSG00000125910 "Sphingosine-1-phosphate receptor 4" O95977 19 3172346-3180332 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.6;lymphoid tissue: 61.1" "Cell type enhanced" "Detected in some" "B-cells: 62.3;dendritic cells: 76.7;monocytes: 33.7;NK-cells: 140.1;T-cells: 64.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 2.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 24.0;HL-60: 32.2;NB-4: 31.7;REH: 89.2;U-937: 30.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060601, HPA067232" Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA060601: AB_2797261, HPA067232: AB_2797271" "prognostic favorable (3.13e-4)" "prognostic favorable (1.33e-4)" "unprognostic (2.58e-2)" "prognostic favorable (2.22e-4)" "unprognostic (2.98e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.27e-2)" "unprognostic (8.73e-2)" "unprognostic (1.21e-3)" "unprognostic (6.64e-3)" "unprognostic (3.59e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (6.15e-3)" 4.6 1.0 0.3 10.7 0.2 19.6 2.8 0.1 2.4 1.0 0.2 2.3 1.1 0.9 0.0 2.3 2.3 1.0 1.6 0.2 0.1 1.7 1.6 11.9 16.5 0.3 0.1 0.3 0.7 0.1 0.3 1.4 0.6 1.3 0.2 0.0 1.2 0.1 0.6 0.8 13.6 0.5 0.2 61.1 4.9 0.2 0.5 4.8 2.9 0.7 4.8 2.8 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 10.9 0.3 0.0 0.0 0.3 0.0 0.1 0.0 24.0 0.0 10.2 0.2 0.0 0.0 32.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 31.7 0.0 0.3 0.0 89.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.3 0.0 0.0 0.1 0.0 3.5 0.0 30.4 0.0 53.2 28.3 81.0 31.1 32.5 27.2 32.3 37.9 29.9 20.4 39.3 31.6 30.2 120.8 16.3 44.7 18.1 67.6 21.6 0.3 0.2 0.1 2.4 0.2 0.1 0.3 0.1 0.6 0.2 0.5 0.1 6.3 3.2 4.6 0.0 62.3 1.3 0.2 0.8 0.0 0.0 0.4 0.3 0.4 1.5 1.9 1.8 0.0 0.2 76.7 0.2 0.0 0.1 0.1 0.4 0.1 4.1 0.0 17.0 0.0 0.2 0.2 0.5 3.1 0.3 5.7 0.0 6.8 0.8 25.2 0.0 0.0 0.0 0.0 27.6 8.3 0.0 0.0 27.8 1.8 0.0 33.7 0.0 140.1 0.0 0.0 0.1 0.0 0.0 27.7 0.3 0.0 0.3 2.7 0.0 0.0 0.5 0.3 0.0 0.0 0.1 1.4 0.0 64.0 0.0 0.0 0.6 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIPA1 SPA1 ENSG00000213445 "Signal-induced proliferation-associated 1" Q96FS4 11 65638101-65650918 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.6" "Cell type enhanced" "Detected in many" "dendritic cells: 82.5;NK-cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020833, HPA039867" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB020833: , HPA039867: AB_2676716" "unprognostic (6.10e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (1.35e-2)" "unprognostic (2.93e-1)" "unprognostic (2.32e-2)" "unprognostic (3.35e-2)" "unprognostic (1.09e-1)" "unprognostic (3.30e-2)" "unprognostic (6.44e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.60e-1)" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-1)" 21.6 17.2 16.4 48.7 15.5 53.8 16.2 14.1 16.8 20.6 10.3 24.0 12.5 20.9 3.4 14.3 19.5 16.0 25.7 15.8 13.2 17.0 15.0 37.0 60.7 22.3 16.0 13.1 8.4 3.5 7.5 19.4 19.5 17.1 6.0 0.9 14.1 10.0 10.0 8.1 37.8 12.0 19.5 95.6 15.9 4.7 24.5 21.3 14.9 6.4 32.5 18.8 15.3 21.0 1.6 13.3 9.1 20.1 5.4 11.1 21.7 14.9 12.7 11.7 11.3 3.9 14.5 21.3 33.2 7.6 0.4 7.8 3.4 5.1 3.9 22.7 8.1 52.6 20.7 7.4 9.6 21.5 21.5 11.4 2.3 16.2 2.1 11.5 34.4 21.8 30.3 9.2 5.8 5.8 8.6 36.1 6.4 5.4 12.3 38.8 5.1 19.3 4.4 0.8 3.4 20.9 7.5 12.6 31.7 8.5 9.6 32.5 49.2 14.2 28.7 15.2 3.0 14.1 12.2 48.4 19.5 33.0 42.0 3.2 3.3 9.3 5.8 3.9 4.1 4.1 2.8 3.7 2.3 4.7 2.0 3.1 11.1 4.7 4.8 2.1 3.0 3.0 16.4 15.5 14.1 16.8 15.8 13.2 22.3 16.0 19.5 19.5 24.5 21.0 22.5 6.4 5.2 7.5 59.0 6.8 24.7 23.2 17.6 2.1 24.8 26.5 7.2 21.5 19.2 23.9 0.0 10.1 82.5 16.5 37.2 19.8 3.0 8.3 6.8 26.8 21.0 31.6 0.1 14.5 19.6 12.2 11.2 14.9 7.0 37.1 42.8 22.0 38.4 5.0 0.2 12.8 30.5 44.4 11.4 9.8 8.1 40.2 10.6 14.0 23.7 7.6 88.6 0.5 4.0 27.2 12.7 13.2 29.6 29.0 39.0 20.7 6.0 1.8 13.1 7.4 20.9 0.8 13.8 14.4 11.1 13.5 50.4 30.9 14.3 31.9 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SLFN12L ENSG00000205045 "Schlafen family member 12 like" Q6IEE8 17 35464249-35487857 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.1" "Group enriched" "Detected in some" 8 "dendritic cells: 16.0;NK-cells: 42.2;T-cells: 31.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 3.6" "Group enriched" "Detected in many" 6 "granulocytes: 1.0;NK-cells: 3.6;T-cells: 1.9" "Cell line enhanced" "Detected in some" "HDLM-2: 9.7;Karpas-707: 5.5" HPA024447 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024447: AB_1856614" "unprognostic (1.93e-3)" "unprognostic (2.10e-4)" "unprognostic (3.77e-2)" "unprognostic (2.67e-2)" "unprognostic (8.18e-3)" "unprognostic (2.98e-5)" "unprognostic (4.59e-3)" "unprognostic (2.75e-2)" "unprognostic (6.82e-2)" "unprognostic (1.67e-2)" "unprognostic (9.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.25e-6)" "unprognostic (2.30e-1)" "unprognostic (3.88e-2)" "unprognostic (7.02e-2)" "unprognostic (8.88e-3)" 0.6 0.3 0.9 2.4 0.9 3.0 0.6 2.5 1.8 0.5 0.9 0.6 1.7 0.5 0.3 0.3 0.3 1.0 0.2 0.7 0.4 0.3 0.6 1.3 3.0 0.3 0.0 0.4 0.3 0.1 0.0 0.2 0.3 0.3 0.8 0.8 0.9 0.2 0.5 0.6 1.5 0.4 0.0 3.1 1.2 0.3 0.5 1.0 0.4 0.3 2.2 0.7 0.1 1.5 0.5 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.6 1.4 0.1 0.3 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.7 9.7 0.1 1.3 0.8 0.1 0.0 0.3 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.3 5.5 0.1 0.0 0.4 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.3 0.2 0.2 0.1 0.4 0.1 0.1 0.1 0.0 2.0 0.6 0.3 1.2 0.5 0.2 2.0 2.0 0.1 0.2 0.3 0.5 1.0 0.3 1.0 1.9 0.0 0.8 0.3 0.8 1.4 0.2 0.3 1.0 1.0 0.9 3.6 0.1 0.2 0.5 0.4 0.9 0.9 2.5 1.8 0.7 0.4 0.3 0.0 0.3 0.0 0.5 1.5 3.5 3.2 2.7 0.0 1.5 0.3 0.6 0.4 0.0 0.0 0.3 0.3 1.3 1.5 0.7 0.0 0.0 0.0 16.0 0.0 0.0 0.2 0.8 0.5 0.2 1.4 0.0 0.4 0.0 0.0 0.0 0.5 1.5 0.3 1.3 0.1 0.4 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.4 0.1 0.0 1.1 0.0 1.0 0.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.2 0.0 0.0 0.5 0.7 0.4 0.0 0.3 0.1 0.0 31.7 0.1 0.1 0.2 SMCHD1 "FSHD2, KIAA0650" ENSG00000101596 "Structural maintenance of chromosomes flexible hinge domain containing 1" A6NHR9 18 2655726-2805017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 363.7;Plasma cells: 391.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 58.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039441 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies" "HPA039441: AB_10671042" "unprognostic (2.99e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-2)" "unprognostic (9.03e-2)" "unprognostic (8.66e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.39e-4)" "unprognostic (1.32e-1)" "unprognostic (4.14e-2)" "unprognostic (3.11e-3)" "unprognostic (3.32e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (8.92e-2)" "unprognostic (2.63e-2)" 13.6 6.9 5.4 24.6 6.6 41.1 12.4 11.4 8.3 16.5 6.8 14.4 13.7 14.9 9.2 8.7 14.1 12.4 10.1 5.0 6.6 6.5 8.4 19.0 33.9 7.2 6.1 15.4 16.3 11.9 7.9 16.3 7.4 13.4 14.7 16.3 10.1 11.2 11.0 9.1 20.3 12.8 6.4 28.6 12.4 14.1 6.3 25.6 9.6 11.5 22.4 15.0 14.2 8.7 24.1 10.7 35.8 22.6 15.0 21.8 25.7 23.7 16.8 22.0 27.7 20.3 7.7 51.6 10.2 21.2 24.7 13.0 29.1 13.6 34.4 10.7 15.1 32.3 21.7 19.5 16.8 93.9 24.3 14.4 12.2 27.9 22.8 16.8 18.3 25.5 38.3 31.1 21.3 8.6 39.4 23.9 14.4 13.0 12.4 31.7 29.1 22.9 13.6 36.5 29.2 18.4 32.0 10.6 18.8 19.8 7.9 39.3 17.5 27.1 37.4 37.1 44.0 18.8 30.4 46.5 17.4 17.1 24.0 5.1 2.5 6.6 3.6 1.7 2.6 5.8 4.8 4.3 0.9 7.5 5.9 3.8 58.7 2.3 2.3 2.6 5.4 1.3 5.4 6.6 11.4 8.3 5.0 6.6 7.2 6.1 7.4 6.4 6.3 8.7 96.5 44.8 44.7 71.5 363.7 27.1 35.3 14.5 48.9 112.1 33.3 32.8 53.0 15.7 27.7 18.4 100.1 36.5 232.7 102.7 5.9 23.4 117.2 43.6 83.3 53.0 22.7 69.0 98.4 19.4 22.3 52.8 68.3 75.9 40.4 54.2 30.7 16.4 19.4 99.3 127.2 35.5 10.2 65.4 69.7 38.6 42.0 116.3 30.2 121.8 142.5 32.3 120.5 111.1 130.4 23.6 60.1 38.0 391.1 52.0 46.5 6.1 22.5 88.5 39.5 59.7 69.8 166.7 115.3 41.3 24.9 46.9 257.9 45.9 30.4 57.8 SMIM35 TMPRSS4-AS1 ENSG00000255274 "Small integral membrane protein 35" A0A1B0GVV1 11 118003634-118088299 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;kidney: 1.1" "Cell type enhanced" "Detected in single" "Collecting duct cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Karpas-707: 10.9;RPMI-8226: 7.2" "Group enriched" "Detected in some" 5 "basal ganglia: 1.2;olfactory bulb: 3.5" "Region enriched" "Detected in some" 6 "basal ganglia: 7.9" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.83e-2)" "unprognostic (3.42e-2)" "unprognostic (2.64e-1)" "unprognostic (1.58e-1)" "unprognostic (3.04e-4)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (1.88e-1)" 0.1 0.1 0.2 0.5 0.3 1.2 0.2 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 1.1 0.1 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.1 0.0 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.3 0.2 0.1 0.0 0.1 0.0 0.4 0.2 0.2 1.6 0.1 0.2 0.3 0.1 0.5 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAF4B "TAF2C2, TAFII105" ENSG00000141384 "TATA-box binding protein associated factor 4b" Q92750 18 26226445-26391685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 80.3;Plasma cells: 52.3;Suprabasal keratinocytes: 78.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 65.0;U-266/70: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028937 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - Translation" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA028937: AB_10603034" "unprognostic (2.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-3)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (5.01e-2)" "unprognostic (2.67e-1)" "unprognostic (3.29e-2)" "unprognostic (2.21e-1)" "unprognostic (4.66e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (7.38e-2)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.72e-4)" 1.5 2.0 0.4 2.8 0.4 2.8 2.7 0.3 1.9 1.2 0.0 1.6 0.4 1.4 0.3 1.0 1.3 0.7 0.4 0.3 0.2 1.5 0.1 1.0 3.1 0.9 0.1 3.1 1.2 0.6 0.2 1.7 1.1 0.8 1.4 0.3 1.1 0.8 1.3 1.5 0.8 1.2 0.0 2.5 1.8 4.6 0.2 1.8 1.7 0.7 3.2 1.5 0.6 0.8 4.3 0.7 0.3 1.1 1.6 2.6 2.1 1.3 1.5 0.7 1.3 1.1 2.3 65.0 5.0 0.3 2.5 4.8 3.7 4.0 3.4 15.5 9.9 7.5 1.9 1.0 2.3 20.5 4.4 4.3 1.5 0.5 11.6 0.6 1.4 8.1 10.2 7.9 0.3 4.2 10.7 4.1 3.5 2.5 5.1 0.0 8.1 17.3 1.0 0.3 6.1 2.8 3.9 5.7 2.7 1.6 2.0 3.6 0.9 2.7 1.6 3.7 4.8 26.2 18.0 21.8 1.3 12.8 2.4 0.0 0.3 0.0 0.1 0.5 1.0 2.3 0.7 1.0 1.0 2.0 2.0 1.6 0.0 0.6 0.2 0.3 0.1 0.6 0.4 0.4 0.3 1.9 0.3 0.2 0.9 0.1 1.1 0.0 0.2 0.8 7.2 6.4 7.2 6.2 34.0 80.3 9.5 1.7 49.5 1.5 15.0 17.9 2.8 0.0 2.5 0.0 0.0 18.6 4.1 5.8 17.6 1.2 0.7 28.9 9.7 9.0 0.0 21.7 44.8 2.0 4.3 15.5 36.7 45.0 1.3 5.4 1.1 0.0 2.4 5.0 28.3 7.0 2.0 1.6 17.9 1.6 3.4 5.9 23.2 4.7 2.6 0.2 1.0 7.5 11.7 2.2 2.5 4.1 52.3 13.9 0.8 4.0 1.0 1.2 0.0 17.6 12.1 25.4 24.8 40.8 78.8 9.7 14.5 14.5 6.2 6.7 TBCC CFC ENSG00000124659 "Tubulin folding cofactor C" Q15814 6 42744498-42746103 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035073, HPA035074" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA035073: AB_10602897, HPA035074: AB_2674448" "unprognostic (7.16e-2)" "unprognostic (9.88e-2)" "unprognostic (2.17e-1)" "unprognostic (4.23e-2)" "unprognostic (8.20e-2)" "unprognostic (6.79e-2)" "unprognostic (5.80e-3)" "unprognostic (1.41e-2)" "unprognostic (2.47e-1)" "unprognostic (3.96e-3)" "unprognostic (1.84e-2)" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (2.28e-1)" "unprognostic (1.29e-1)" "unprognostic (6.31e-2)" "unprognostic (3.76e-3)" 10.4 15.0 15.9 17.8 15.8 39.6 9.9 15.4 18.3 9.9 12.3 17.0 14.5 14.4 12.9 16.1 15.6 10.1 16.0 16.4 16.3 11.9 13.1 11.6 29.1 18.0 14.1 12.2 14.9 11.3 11.1 7.6 18.8 11.3 9.9 15.4 14.5 11.8 26.7 16.8 23.5 10.7 15.2 30.1 15.5 18.0 14.7 21.9 14.0 14.4 19.5 13.1 10.0 16.6 34.5 11.2 16.9 31.7 23.9 16.0 22.3 23.2 26.1 25.3 27.4 17.4 13.3 31.0 18.3 22.7 21.0 29.5 22.9 23.2 14.0 17.0 25.0 16.3 16.7 29.7 27.2 17.9 25.5 26.2 27.8 19.7 16.1 22.7 20.1 17.1 37.8 27.4 22.9 42.4 14.8 34.3 15.8 93.5 30.4 14.8 20.3 20.3 24.5 18.6 64.7 28.1 15.1 25.8 41.1 15.4 28.3 59.7 21.9 24.1 21.6 19.6 32.3 36.1 43.7 53.0 11.8 24.2 23.7 139.1 91.4 174.5 105.5 79.2 108.9 101.7 111.9 116.7 83.5 90.9 129.6 119.9 162.1 170.8 74.1 142.3 154.8 170.4 15.9 15.8 15.4 18.3 16.4 16.3 18.0 14.1 18.8 15.2 14.7 16.6 19.3 3.2 24.0 2.6 50.8 25.1 25.9 49.3 51.2 55.0 25.4 29.1 6.8 24.3 25.7 11.0 41.7 21.4 83.8 25.1 33.2 38.6 30.3 23.0 21.2 20.9 45.3 13.0 7.0 30.9 23.5 17.1 18.3 22.9 31.0 21.0 19.6 10.0 18.8 18.5 7.8 21.2 71.2 16.2 27.8 10.2 17.7 15.9 28.4 8.4 33.6 46.3 77.2 5.0 12.8 28.5 27.0 20.7 37.1 15.9 29.8 23.9 22.0 51.7 19.7 13.0 46.1 50.1 22.7 30.7 24.9 21.1 80.2 26.6 22.3 22.1 TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.1;lung: 3.3;lymphoid tissue: 11.7" "Cell type enhanced" "Detected in some" "dendritic cells: 92.8;NK-cells: 119.4;Plasma cells: 22.8;T-cells: 45.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Cell line enriched" "Detected in single" 113 "HDLM-2: 16.3" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.2" "CAB009524, CAB030043" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB009524: AB_2200557, CAB030043: AB_1595503" "unprognostic (3.31e-3)" "unprognostic (3.17e-3)" "unprognostic (1.17e-2)" "unprognostic (5.35e-6)" "unprognostic (3.93e-1)" "unprognostic (2.56e-4)" "unprognostic (5.86e-4)" "unprognostic (6.90e-2)" "unprognostic (3.63e-3)" "unprognostic (6.26e-4)" "unprognostic (1.43e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-4)" "unprognostic (7.92e-2)" "unprognostic (2.67e-1)" "unprognostic (9.19e-3)" "unprognostic (4.43e-3)" 0.9 0.4 0.3 1.9 0.3 11.1 0.4 0.3 0.3 0.4 0.4 0.5 0.9 0.3 0.4 0.3 0.4 0.8 0.3 0.2 0.3 0.5 1.2 3.3 7.5 0.4 0.3 0.2 0.2 0.0 0.2 0.2 0.3 0.4 0.5 0.0 0.6 0.2 0.5 0.2 1.6 0.4 0.3 11.7 1.2 0.4 0.3 1.0 0.7 0.2 2.2 0.6 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 3.6 2.0 3.1 8.9 0.0 0.5 0.4 7.8 0.2 14.3 0.0 0.1 0.1 2.4 0.3 0.3 0.3 0.3 0.2 0.3 0.4 0.3 0.3 0.3 0.3 0.3 1.1 0.0 0.6 0.0 7.6 0.0 0.0 0.0 0.6 0.0 0.6 0.9 1.3 1.5 0.0 0.0 0.0 0.1 92.8 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 1.3 0.1 0.0 0.0 0.2 1.1 0.2 2.5 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 1.9 0.0 1.9 0.8 0.0 119.4 0.0 0.1 0.0 0.0 0.0 22.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.1 0.0 45.6 0.0 0.0 0.0 TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 45.5;Kupffer cells: 56.3;Macrophages: 61.6;Microglial cells: 60.0;monocytes: 44.1;Proximal tubular cells: 77.8" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Cell line enhanced" "Detected in some" "HEL: 15.9;HUVEC TERT2: 11.0;THP-1: 21.5;TIME: 12.5;U-937: 24.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA063577" Approved Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB032260: AB_2202845, HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" 3.5 2.4 1.3 19.2 1.2 17.2 2.6 1.5 1.6 1.9 2.1 2.7 4.2 1.4 0.6 1.0 1.0 4.9 1.0 0.8 1.7 20.5 3.1 9.9 22.1 3.3 1.9 1.3 1.0 0.4 0.6 4.7 2.7 1.0 4.2 0.1 1.3 0.9 0.3 0.4 9.7 3.1 2.7 14.6 3.0 1.6 3.7 2.8 0.9 0.4 12.6 4.0 0.6 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 1.7 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 21.5 12.5 2.1 0.2 1.3 0.0 5.5 0.0 0.0 0.1 24.4 1.1 0.0 7.1 0.0 0.0 2.8 0.0 3.8 0.0 0.0 6.3 2.5 0.0 0.0 0.1 0.0 0.4 3.3 0.0 1.5 1.3 1.2 1.5 1.6 0.8 1.7 3.3 1.9 2.7 2.7 3.7 4.8 0.5 0.0 2.2 0.3 18.1 0.5 0.0 0.0 0.0 0.0 0.3 0.8 0.8 1.5 0.0 3.7 0.0 0.2 8.3 0.0 0.0 0.0 2.4 0.0 0.0 1.7 0.0 7.2 0.6 0.0 0.3 0.4 0.0 0.0 2.5 0.0 0.0 0.0 45.5 0.0 0.5 0.4 0.0 56.3 17.8 3.8 0.0 61.6 0.0 60.0 44.1 0.0 1.0 1.0 0.1 0.1 0.0 0.0 1.3 0.1 15.6 77.8 0.0 0.0 0.0 0.3 0.1 0.3 2.5 0.1 0.4 0.8 0.8 0.1 0.7 0.1 THOC6 "fSAP35, MGC2655, WDR58" ENSG00000131652 "THO complex 6" Q86W42 16 3024027-3027755 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transport" "Developmental protein, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.8;Extravillous trophoblasts: 121.1;Prostatic glandular cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052953 Uncertain Supported "Nucleoplasm,Nuclear speckles" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA052953: AB_2681997" "unprognostic (2.07e-2)" "unprognostic (4.13e-3)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (7.82e-3)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (3.59e-1)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (9.43e-2)" 17.0 16.9 8.6 16.1 9.1 23.5 15.3 9.6 11.2 16.1 9.7 17.9 18.8 20.3 6.0 19.3 13.9 10.5 15.8 8.6 9.2 22.2 21.3 17.5 20.8 11.6 9.1 11.6 12.9 10.8 17.4 18.2 11.8 21.1 10.1 2.1 15.2 12.2 25.9 24.9 19.2 12.5 9.2 22.7 15.6 10.4 10.2 19.6 15.7 8.4 16.1 17.1 16.5 9.5 37.3 59.6 42.0 45.0 21.1 23.9 74.4 11.3 25.7 25.7 37.8 39.6 42.8 70.0 36.0 18.9 19.1 49.9 46.3 35.6 14.0 62.3 59.9 38.0 58.6 58.7 35.9 56.2 80.0 24.3 42.6 31.4 76.9 32.4 24.1 39.7 56.1 36.5 12.8 87.0 32.0 103.3 76.2 21.4 25.3 84.7 31.6 82.4 27.1 18.6 86.4 41.0 31.8 49.9 21.7 18.1 35.9 60.0 20.1 26.8 61.1 30.6 41.3 26.3 24.3 85.5 7.0 38.1 27.3 2.4 61.3 13.6 35.2 62.2 36.2 37.8 32.6 34.7 88.6 43.2 37.1 39.1 4.4 38.8 35.7 74.3 38.0 45.4 8.6 9.1 9.6 11.2 8.6 9.2 11.6 9.1 11.8 9.2 10.2 9.5 11.0 19.2 7.4 1.6 24.7 68.2 84.9 59.0 30.7 3.7 22.1 20.8 3.3 14.3 18.9 18.4 2.1 107.8 23.3 23.2 35.2 33.1 5.4 17.9 19.0 17.9 25.8 30.3 1.9 23.5 121.1 24.6 15.3 25.8 12.0 15.6 6.4 10.3 51.8 3.3 1.7 32.3 44.7 19.4 37.3 3.2 14.9 23.4 24.9 2.8 39.6 3.2 15.5 0.5 4.2 21.5 28.0 12.0 19.7 109.4 32.1 32.0 8.7 2.4 6.6 23.4 31.9 5.3 23.3 23.3 44.9 77.2 20.4 20.9 42.2 46.8 TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 49.8;Macrophages: 21.1;monocytes: 39.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" 3.6 0.5 0.2 16.8 0.2 5.7 0.9 0.2 0.3 0.7 0.5 1.7 0.8 0.4 0.1 0.9 0.6 2.5 0.8 0.1 0.3 0.5 2.2 10.7 6.1 1.1 0.7 0.4 0.6 0.3 0.1 4.3 0.8 0.3 1.8 0.0 0.3 0.2 0.2 0.2 1.5 3.8 0.5 13.3 0.8 0.4 0.4 1.7 0.4 1.3 1.9 3.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 14.9 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.0 27.6 0.0 15.6 0.0 0.0 3.8 0.2 0.2 0.2 0.3 0.1 0.3 1.1 0.7 0.8 0.5 0.4 0.9 0.0 0.0 3.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.7 5.3 0.0 0.0 0.0 0.0 49.8 5.1 0.0 0.0 21.1 0.0 0.0 39.7 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TMC2 "C20orf145, dJ686C3.3" ENSG00000149488 "Transmembrane channel like 2" Q8TDI7 20 2536573-2643580 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lung: 1.1;pituitary gland: 1.8" "Group enriched" "Detected in some" 6 "Late spermatids: 11.4;Oligodendrocyte precursor cells: 32.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 2: Immune cells - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (4.73e-2)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (8.30e-4)" "unprognostic (2.86e-3)" "unprognostic (3.00e-1)" "unprognostic (1.13e-2)" "unprognostic (1.07e-2)" "unprognostic (4.54e-1)" "unprognostic (1.41e-2)" "unprognostic (4.05e-5)" "unprognostic (2.90e-1)" "unprognostic (3.21e-7)" "unprognostic (2.47e-2)" "unprognostic (2.56e-1)" "unprognostic (1.93e-1)" "unprognostic (5.74e-2)" 0.8 0.1 0.2 0.1 0.2 0.1 0.5 1.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.4 0.0 0.2 0.3 0.0 0.0 1.1 0.1 0.1 0.0 0.2 0.2 0.0 1.8 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 1.0 0.2 0.2 0.3 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 1.9 0.0 0.0 0.0 32.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 TMC8 "EVER2, EVIN2" ENSG00000167895 "Transmembrane channel like 8" Q8IU68 17 78130770-78142968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;intestine: 54.6;lymphoid tissue: 117.0" "Cell type enhanced" "Detected in many" "B-cells: 44.9;dendritic cells: 52.3;granulocytes: 41.2;Langerhans cells: 44.6;NK-cells: 85.5;T-cells: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 46.3;HL-60: 63.0;HMC-1: 119.9;Karpas-707: 103.9;RPMI-8226: 66.6;U-266/70: 49.3;U-937: 51.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047387, HPA054429" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA047387: , HPA054429: AB_2682485" "unprognostic (8.54e-3)" "prognostic favorable (8.45e-6)" "unprognostic (1.32e-1)" "unprognostic (2.33e-3)" "unprognostic (3.59e-1)" "prognostic favorable (4.19e-5)" "unprognostic (6.38e-3)" "unprognostic (6.47e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (6.06e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.24e-2)" "unprognostic (1.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" 7.8 3.0 3.6 56.0 4.4 91.8 3.7 3.7 5.1 3.7 3.5 8.2 10.3 2.5 0.7 4.8 4.0 7.4 2.7 3.6 4.8 5.2 7.1 18.4 100.5 5.8 4.7 1.3 2.0 0.5 2.2 3.9 5.6 4.9 4.5 0.1 5.8 1.3 1.8 3.6 54.6 2.4 5.0 117.0 10.4 1.2 7.8 60.1 6.4 0.9 46.7 6.4 5.0 7.2 0.5 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.3 46.3 2.0 0.0 0.1 3.4 0.0 0.1 0.0 0.0 0.1 16.4 0.1 0.8 0.0 63.0 119.9 0.0 0.0 0.0 0.0 0.0 0.0 22.1 4.0 103.9 0.0 1.3 20.9 2.8 0.2 3.5 0.5 1.4 0.3 66.6 0.0 0.2 0.0 0.1 0.0 2.2 0.6 0.1 6.9 12.7 0.1 0.0 0.1 0.1 0.0 49.3 2.0 4.6 0.1 51.9 0.1 2.6 2.0 6.6 13.4 3.4 9.7 5.5 10.8 13.3 2.3 4.8 9.4 8.6 3.3 7.5 7.9 2.1 6.5 5.5 3.6 4.4 3.7 5.1 3.6 4.8 5.8 4.7 5.6 5.0 7.8 7.2 3.6 3.2 10.2 1.0 44.9 5.4 10.4 4.9 4.6 0.2 1.2 1.5 1.9 1.5 6.5 0.0 0.0 0.4 52.3 3.7 0.0 1.0 0.7 1.0 0.6 3.2 1.2 17.1 0.4 1.3 1.4 2.3 2.0 1.8 41.2 0.1 5.7 0.5 30.5 0.0 0.4 1.4 14.2 28.2 44.6 0.5 0.0 22.0 7.2 24.4 30.2 0.2 85.5 1.0 2.7 0.6 3.6 0.4 20.2 2.9 0.9 0.4 2.1 0.2 0.0 0.3 2.0 0.4 0.6 8.4 4.5 0.5 68.6 2.7 7.0 10.7 TRGV10 "TCRGV10, V3P" ENSG00000211694 "T cell receptor gamma variable 10 (non-functional)" 7 38299811-38300322 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.5;Plasma cells: 7.1;T-cells: 29.9" "Cancer enriched" "Detected in many" 8 "prostate cancer: 7.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 196.5" "Lineage enriched" "Detected in many" 8 "T-cells: 196.5" "Group enriched" "Detected in some" 24 "NB-4: 79.7;U-937: 20.5" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.59e-2)" "unprognostic (4.53e-3)" "unprognostic (5.13e-2)" "unprognostic (2.94e-3)" "unprognostic (1.54e-2)" "unprognostic (1.22e-4)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.53e-2)" "unprognostic (1.94e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-4)" "unprognostic (2.68e-1)" "unprognostic (9.00e-2)" "unprognostic (5.10e-2)" "unprognostic (2.07e-2)" 1.7 0.6 0.1 2.7 0.3 14.1 1.8 0.1 0.4 1.2 0.6 2.0 2.1 0.8 0.7 1.1 1.3 3.3 0.4 0.0 0.1 0.6 1.8 4.1 11.0 0.4 0.1 0.3 0.2 0.1 0.2 0.4 0.3 6.1 2.7 0.0 1.1 0.7 0.2 0.6 4.1 0.6 0.2 13.9 2.6 0.3 0.2 12.5 1.1 0.0 5.0 3.8 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 79.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.5 0.0 0.7 0.4 1.0 196.5 0.1 156.1 0.5 47.2 137.6 0.2 0.1 11.3 159.7 2.9 26.0 0.3 0.8 0.1 33.3 0.1 0.3 0.1 0.4 0.0 0.1 0.4 0.1 0.3 0.2 0.2 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 29.9 0.0 0.0 0.0 TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 50.0;Hofbauer cells: 50.6;monocytes: 39.4;NK-cells: 49.4" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 78.8;fHDF/TERT166: 108.4;HMC-1: 89.0;SK-MEL-30: 94.7;TIME: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" 17.1 20.5 6.2 18.3 8.0 22.8 10.4 5.7 7.6 7.9 3.9 7.0 6.6 7.6 1.8 5.3 7.3 8.5 11.2 6.1 9.8 4.7 4.0 30.2 24.6 10.6 15.4 7.8 6.3 8.9 1.6 20.1 17.2 6.0 6.2 1.0 4.5 2.6 3.9 6.5 10.7 11.8 7.1 23.7 5.9 2.0 7.3 15.7 6.2 5.5 16.2 10.7 7.2 8.0 0.3 1.6 0.0 0.0 25.6 78.8 4.9 8.3 9.4 9.1 8.9 0.3 0.3 9.6 2.2 108.4 7.8 0.2 0.2 0.0 5.1 43.0 0.7 10.7 0.0 26.1 30.0 14.8 89.0 35.2 0.0 54.0 0.7 4.1 3.8 12.9 37.2 26.0 43.4 0.5 19.1 20.5 0.1 0.1 0.2 11.3 0.3 4.3 40.6 1.1 1.2 0.1 0.0 0.0 94.7 41.0 0.0 12.7 84.9 0.2 0.3 0.3 1.1 0.1 0.3 5.1 8.2 21.6 12.6 60.8 26.6 35.8 63.4 52.8 55.5 19.2 46.0 59.3 58.7 20.3 25.7 44.8 6.8 63.2 49.4 51.3 49.9 43.1 6.2 8.0 5.7 7.6 6.1 9.8 10.6 15.4 17.2 7.1 7.3 8.0 15.8 0.0 5.3 1.0 11.1 2.8 0.1 0.0 0.0 0.6 0.5 0.4 1.1 1.5 0.6 0.0 0.0 2.2 29.3 0.0 0.0 0.2 0.3 0.4 0.1 12.3 0.0 6.7 3.3 3.6 2.3 11.0 1.1 0.1 50.0 16.7 8.9 0.4 50.6 0.0 2.6 0.0 0.0 19.5 18.2 0.0 1.8 28.7 28.4 4.7 39.4 0.3 49.4 0.5 0.5 4.7 0.1 4.5 15.1 0.0 0.0 0.1 0.8 0.6 26.3 7.9 23.6 1.3 5.9 0.4 1.7 16.1 26.8 2.8 0.0 0.1 UNC13D Munc13-4 ENSG00000092929 "Unc-13 homolog D" Q70J99 17 75827225-75844552 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Exocytosis "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.9;lymphoid tissue: 66.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 68.3;Hofbauer cells: 58.5;NK-cells: 61.8;Pancreatic endocrine cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 245.7;HeLa: 136.3;HMC-1: 245.9;SK-BR-3: 189.7" "Region enriched" "Detected in single" 6 "cerebellum: 5.0" "Low region specificity" "Detected in many" "HPA067117, HPA073525" Enhanced Supported Vesicles,Cytosol NA NA 1500000 "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol Vesicles "HPA067117: AB_2685784, HPA073525: AB_2686615" "unprognostic (6.79e-3)" "unprognostic (4.36e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.98e-2)" "unprognostic (1.42e-3)" "unprognostic (3.93e-1)" "unprognostic (1.37e-2)" "unprognostic (2.74e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (5.28e-12)" "unprognostic (3.27e-2)" "unprognostic (5.58e-2)" "unprognostic (1.56e-1)" "unprognostic (8.59e-2)" 7.7 7.3 5.6 23.5 6.8 58.9 7.8 5.8 7.3 18.6 5.0 10.7 8.0 8.6 2.0 23.6 13.8 6.5 14.3 5.0 5.6 6.6 12.6 38.1 25.9 7.9 6.5 19.3 8.8 0.5 11.6 9.0 7.5 8.1 4.5 5.5 7.7 5.1 8.5 6.0 18.5 4.9 6.2 66.2 13.8 6.1 8.2 20.7 5.9 1.5 17.6 10.7 19.6 8.7 44.0 18.7 0.4 0.3 0.5 1.0 47.6 0.1 0.0 0.0 0.1 41.4 97.0 3.4 46.4 0.0 7.5 15.4 0.0 2.2 0.0 0.4 0.5 245.7 136.3 24.2 3.9 94.1 245.9 0.6 2.0 0.5 2.1 2.3 17.9 42.5 87.1 1.1 0.0 71.2 100.9 50.8 0.9 69.9 1.7 32.8 1.0 1.5 1.6 17.7 0.3 66.7 19.2 189.7 0.9 0.5 47.1 56.5 48.1 0.8 65.9 0.5 0.5 1.3 5.9 4.0 0.6 31.3 0.2 59.1 16.0 31.2 19.3 16.9 17.4 6.7 11.4 13.6 12.3 3.6 8.8 11.9 40.1 14.7 25.6 7.2 10.8 18.1 5.6 6.8 5.8 7.3 5.0 5.6 7.9 6.5 7.5 6.2 8.2 8.7 3.8 44.8 8.3 6.8 16.6 1.1 1.7 1.0 0.6 12.0 4.9 2.4 68.3 7.2 4.4 3.7 20.9 4.7 27.0 40.9 0.0 7.2 5.3 1.3 3.3 6.6 6.0 14.9 1.2 6.0 11.6 2.2 2.0 2.3 45.0 9.9 7.9 1.2 58.5 5.0 1.5 3.6 2.0 21.6 8.2 0.5 2.8 22.2 1.8 5.6 22.5 4.5 61.8 3.0 7.9 47.3 30.7 1.5 27.4 1.6 5.5 0.7 1.6 16.2 0.0 4.5 2.6 1.2 1.4 1.5 1.4 25.9 30.9 2.0 6.3 2.3 USPL1 "bA121O19.1, C13orf22, D13S106E" ENSG00000132952 "Ubiquitin specific peptidase like 1" Q5W0Q7 13 30617693-30660770 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 135.8;Late spermatids: 306.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039342, HPA040172" Uncertain NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA039342: AB_10795105, HPA040172: AB_10796447" "unprognostic (5.74e-2)" "unprognostic (6.26e-2)" "unprognostic (8.16e-2)" "unprognostic (4.29e-2)" "unprognostic (4.96e-2)" "unprognostic (3.65e-1)" "unprognostic (1.00e-2)" "unprognostic (1.65e-1)" "unprognostic (1.20e-1)" "unprognostic (6.79e-2)" "unprognostic (2.21e-2)" "unprognostic (1.27e-2)" "unprognostic (3.18e-1)" "unprognostic (2.68e-1)" "unprognostic (1.49e-1)" "unprognostic (3.78e-1)" "unprognostic (5.32e-3)" 11.9 9.9 8.0 8.5 8.5 24.1 11.3 11.0 12.0 10.3 7.9 10.7 6.3 10.9 7.1 7.3 10.0 6.2 8.0 8.5 8.1 12.0 15.6 11.8 12.9 8.0 8.0 13.2 12.1 4.7 8.9 8.2 8.2 10.9 6.5 15.6 9.0 6.6 9.4 9.7 13.7 6.3 8.4 18.6 10.0 19.4 8.4 9.3 10.9 8.3 11.5 10.6 9.6 11.2 4.5 6.5 14.7 9.5 7.5 9.0 6.2 10.1 7.9 9.8 7.9 9.1 11.5 10.1 5.0 8.6 12.8 9.1 16.2 6.1 14.4 8.5 6.6 12.6 10.4 8.0 6.7 12.1 9.6 6.8 10.7 7.2 10.1 14.2 14.2 10.9 12.4 6.6 10.8 3.9 17.3 25.3 12.6 15.0 4.2 15.3 11.3 9.5 7.9 3.0 13.0 11.7 5.5 6.4 9.5 11.3 7.1 15.1 9.0 6.8 6.7 9.2 7.9 6.7 6.3 14.5 3.9 8.7 13.6 3.1 3.8 3.7 3.5 2.8 5.0 5.3 3.4 3.7 3.5 5.7 4.7 4.3 1.8 4.5 2.3 2.6 4.2 3.1 8.0 8.5 11.0 12.0 8.5 8.1 8.0 8.0 8.2 8.4 8.4 11.2 17.6 16.0 9.8 17.3 30.2 4.5 6.6 4.5 17.1 10.1 9.0 8.4 18.2 5.7 7.4 7.3 16.7 4.3 18.6 6.3 3.9 5.1 135.8 9.3 19.6 13.9 14.3 9.5 19.6 4.5 5.9 13.7 13.7 12.1 1.3 9.4 11.0 6.9 7.0 15.2 23.0 11.7 6.1 10.1 15.4 306.1 6.8 18.2 3.6 19.7 6.9 8.9 10.3 21.6 26.8 5.5 5.6 5.3 24.2 8.5 5.7 3.5 6.4 12.0 6.6 13.1 12.6 16.4 8.8 15.5 3.8 3.1 18.2 10.1 8.8 5.0 VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "Ductal cells: 63.6;Ionocytes: 22.4;Macrophages: 41.1;monocytes: 57.5;Respiratory ciliated cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 477.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 477.4" "Cell line enriched" "Detected in some" 7 "Daudi: 59.7" "Low region specificity" "Detected in some" NA NA 240000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.60e-3)" "unprognostic (5.71e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-3)" "unprognostic (1.98e-3)" "unprognostic (4.38e-1)" "unprognostic (3.07e-1)" "unprognostic (3.46e-1)" "unprognostic (2.84e-1)" "unprognostic (8.30e-2)" "prognostic unfavorable (2.72e-7)" "unprognostic (1.62e-1)" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (5.45e-2)" 21.7 2.7 0.6 23.9 0.9 31.6 1.3 0.7 2.8 4.3 1.4 3.8 2.4 1.3 0.4 4.1 5.3 22.5 2.3 0.5 0.7 2.4 10.1 22.5 39.0 1.5 1.0 1.5 4.3 0.7 0.9 20.7 1.7 1.8 3.0 0.1 1.5 0.9 0.6 0.3 4.6 6.3 0.8 56.6 7.3 0.6 1.0 11.7 1.2 7.9 42.0 17.8 1.2 1.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 59.7 1.1 0.0 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 1.1 1.4 0.0 0.0 11.6 65.2 0.3 24.6 14.5 10.3 40.3 8.4 29.0 14.1 32.2 27.0 39.4 477.4 36.1 9.9 2.6 6.1 40.4 0.6 0.9 0.7 2.8 0.5 0.7 1.5 1.0 1.7 0.8 1.0 1.0 0.2 0.0 6.7 0.0 11.0 0.0 0.5 4.3 0.0 0.0 0.2 0.0 1.5 7.2 11.8 0.0 0.0 0.8 10.9 0.1 0.0 63.6 0.0 0.3 0.0 1.4 0.0 1.3 0.2 0.4 0.2 1.9 13.3 0.2 5.1 0.1 3.3 1.0 13.9 0.0 0.0 0.0 22.4 18.6 1.0 0.0 0.0 41.1 0.0 1.9 57.5 0.3 20.6 0.0 0.1 3.6 0.0 0.0 2.7 8.0 0.0 0.6 25.4 0.1 6.6 2.5 1.2 0.1 0.0 0.1 0.0 1.4 10.9 6.5 0.2 14.5 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Cell line enhanced" "Detected in some" "Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 10.2 5.2 6.3 52.2 5.8 58.4 4.4 5.9 8.1 3.3 6.3 6.4 8.0 2.8 3.0 3.5 5.6 6.9 3.5 6.0 8.0 4.4 7.2 19.1 54.2 11.1 8.2 1.8 2.4 1.4 2.9 9.0 8.6 4.2 5.0 0.4 4.9 2.8 1.4 2.8 23.0 6.1 8.0 83.0 7.0 1.9 8.6 42.0 3.5 3.4 36.2 10.3 3.0 10.8 0.8 0.2 0.4 1.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.9 76.5 0.3 0.0 0.3 2.0 0.3 0.2 0.0 44.2 0.4 67.6 0.9 0.0 0.8 34.9 157.0 0.3 0.1 0.1 0.0 0.0 0.0 40.3 0.7 45.7 0.0 7.6 70.8 75.7 0.4 1.1 0.4 61.1 0.3 94.0 0.1 0.0 0.5 0.9 1.0 0.7 0.5 0.2 0.4 68.8 0.5 0.1 0.4 1.2 0.1 83.1 43.6 53.7 0.5 87.4 0.2 3.3 7.6 37.4 4.6 8.4 3.4 3.0 3.5 3.9 5.7 3.3 3.1 3.5 29.2 3.6 9.5 3.1 5.4 4.0 6.3 5.8 5.9 8.1 6.0 8.0 11.1 8.2 8.6 8.0 8.6 10.8 1.5 3.2 14.3 0.7 83.2 2.4 0.2 0.2 2.2 0.2 1.1 1.8 1.1 0.0 0.1 0.0 0.0 0.9 91.7 0.3 1.9 0.4 0.6 0.4 0.4 2.6 1.2 14.1 0.3 0.4 1.1 1.5 5.6 0.3 48.1 0.2 3.9 1.6 111.5 0.0 0.3 0.2 0.0 110.7 54.5 1.1 0.0 118.1 3.6 4.7 88.2 0.2 84.5 0.5 0.0 0.1 0.1 0.0 57.8 0.2 0.1 1.8 1.6 0.2 0.0 1.0 1.3 1.3 1.1 0.8 1.4 1.4 99.3 0.4 0.1 0.2 XCL1 "ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1" ENSG00000143184 "X-C motif chemokine ligand 1" P47992 1 168576605-168582069 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6" "Group enriched" "Detected in many" 4 "dendritic cells: 185.3;T-cells: 213.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "NK-cell: 88.5" "Lineage enriched" "Detected in many" 14 "NK-cells: 88.5" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 4.1;SCLC-21H: 3.3;SuSa: 6.1;U-266/70: 5.0;U-266/84: 1.9" "Not detected" "Not detected" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (5.38e-3)" "unprognostic (5.72e-2)" "unprognostic (8.23e-3)" "unprognostic (4.19e-3)" "unprognostic (1.43e-1)" "unprognostic (6.10e-2)" "unprognostic (2.96e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (4.61e-1)" "unprognostic (8.85e-2)" "unprognostic (5.34e-10)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (5.47e-2)" "unprognostic (2.15e-2)" 0.5 0.1 0.1 1.0 0.1 3.5 1.0 0.0 0.2 1.0 0.0 0.7 1.0 2.2 0.8 0.2 0.6 1.1 0.5 0.1 0.2 0.5 2.6 1.8 2.3 0.1 0.1 0.2 0.5 0.0 0.1 2.2 0.2 0.4 1.0 0.0 1.5 0.3 0.1 0.1 1.5 0.3 0.1 4.6 1.2 0.2 0.6 4.1 0.3 0.0 1.6 0.9 0.4 0.1 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.3 0.0 0.3 0.0 0.0 6.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 5.0 1.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 6.2 0.0 0.2 0.0 1.0 5.9 0.0 0.0 0.3 4.0 0.3 88.5 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.6 0.1 2.3 3.2 5.5 0.0 1.5 4.0 0.5 0.0 2.2 0.0 1.3 1.5 2.0 1.5 0.0 0.0 0.0 1.4 185.3 0.7 0.0 0.0 1.3 2.0 1.9 1.9 0.0 8.4 0.0 0.2 1.2 1.9 8.2 2.9 2.5 0.0 1.4 0.9 0.4 0.0 0.1 0.8 0.0 1.9 10.6 0.0 0.0 3.1 39.2 0.0 0.1 0.0 42.2 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 0.3 1.7 0.2 0.2 1.8 4.3 0.8 213.4 0.0 0.4 0.1 XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.4" "Group enriched" "Detected in many" 10 "dendritic cells: 513.6;NK-cells: 277.1;T-cells: 240.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 423.5" "Lineage enriched" "Detected in many" 8 "NK-cells: 423.5" "Cell line enhanced" "Detected in some" "CACO-2: 3.0;RT4: 1.1;SuSa: 1.1" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" 1.1 0.8 0.3 3.2 0.3 14.1 0.9 0.3 0.5 1.0 0.4 1.9 3.2 3.6 0.9 0.6 1.8 1.9 0.7 0.3 0.4 0.4 5.6 3.3 5.6 0.5 0.3 0.4 0.6 0.3 0.2 1.4 0.4 0.5 1.5 0.0 1.9 1.0 0.3 0.1 2.0 1.4 0.4 13.4 2.9 0.3 0.6 3.8 0.6 0.5 3.6 2.0 0.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.4 47.2 0.2 2.7 0.3 3.6 50.1 0.3 0.1 2.1 37.1 1.9 423.5 0.3 0.1 0.0 17.1 0.3 0.3 0.3 0.5 0.3 0.4 0.5 0.3 0.4 0.4 0.6 0.4 2.9 0.0 1.1 0.0 3.3 2.4 0.0 0.0 1.8 0.0 1.6 1.4 0.8 0.0 0.0 0.0 0.0 0.1 513.6 0.3 0.0 0.1 0.0 2.4 2.0 1.0 0.0 19.2 0.0 0.0 0.0 1.1 8.2 2.2 1.3 0.0 1.4 0.6 0.4 0.0 0.0 0.7 0.0 5.0 4.0 0.0 0.0 3.7 33.8 0.0 0.8 0.0 277.1 0.0 0.0 0.0 1.1 0.0 13.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.9 1.1 0.0 240.6 0.0 0.1 0.1 ZBP1 "C20orf183, DAI, dJ718J7.3, DLM-1, DLM1" ENSG00000124256 "Z-DNA binding protein 1" Q9H171 20 57603846-57620576 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Necrosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.7;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 34.0;dendritic cells: 42.7;NK-cells: 53.5;Plasma cells: 189.2;T-cells: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 34.1;U-266/70: 16.6;U-266/84: 22.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA041256 Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA041256: AB_2677380" "unprognostic (5.78e-3)" "unprognostic (9.86e-2)" "unprognostic (6.14e-2)" "unprognostic (6.20e-2)" "unprognostic (6.65e-2)" "unprognostic (1.05e-4)" "unprognostic (1.37e-2)" "unprognostic (1.31e-1)" "unprognostic (1.19e-3)" "unprognostic (1.38e-3)" "unprognostic (7.19e-2)" "unprognostic (2.58e-1)" "unprognostic (1.58e-8)" "unprognostic (8.29e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-2)" "unprognostic (9.79e-2)" 2.6 1.4 0.6 18.8 0.7 28.7 3.6 4.6 2.8 2.1 0.1 9.8 13.1 1.9 2.2 2.1 1.0 7.8 1.9 1.5 0.0 1.3 2.1 5.1 23.9 0.6 0.2 1.8 2.0 0.2 0.4 1.3 1.3 1.8 10.8 4.1 6.2 1.6 0.8 3.9 10.6 1.2 0.7 21.8 8.4 2.2 0.4 5.0 2.7 1.3 25.1 8.5 0.8 2.9 0.8 0.6 1.9 3.5 0.6 0.5 1.0 0.6 0.3 0.2 0.9 3.0 1.6 9.3 0.7 0.0 1.1 1.5 0.0 1.1 0.0 0.8 2.0 2.9 5.5 1.4 0.5 2.5 2.2 0.0 0.4 1.1 0.9 1.8 0.4 1.5 1.2 34.1 1.3 4.7 1.5 4.8 2.2 0.5 4.1 1.4 0.2 10.0 0.0 4.3 1.9 2.0 0.3 1.6 1.4 1.3 1.3 1.4 1.6 4.3 1.5 2.8 1.6 16.6 22.8 4.1 1.6 2.8 0.8 1.6 3.8 17.5 18.8 3.9 12.5 16.2 12.6 11.4 4.4 12.1 5.6 7.8 38.0 19.6 2.4 0.2 18.4 7.0 0.6 0.7 4.6 2.8 1.5 0.0 0.6 0.2 1.3 0.7 0.4 2.9 1.2 0.0 0.6 0.0 34.0 0.3 1.0 0.2 0.0 0.0 0.5 0.3 1.0 0.0 0.0 0.0 2.1 0.1 42.7 12.9 0.0 0.1 0.1 0.1 0.2 0.5 0.0 0.8 0.0 0.2 0.0 0.5 3.1 0.4 3.8 0.0 0.0 0.0 1.0 0.0 0.1 1.1 0.0 1.0 0.4 0.0 0.0 2.1 14.2 0.0 3.1 0.5 53.5 0.0 0.1 1.3 3.4 0.0 189.2 1.8 0.8 0.2 0.0 0.3 0.0 1.5 0.8 0.0 0.0 0.0 0.3 0.0 25.8 0.0 1.0 0.8 ZNF354A "EZNF, HKL1, KID-1, KID1, TCF17" ENSG00000169131 "Zinc finger protein 354A" O60765 5 178711512-178730659 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 49.6" "Low region specificity" "Detected in all" HPA052043 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" Cytosol "HPA052043: AB_2681706" "unprognostic (2.79e-1)" "unprognostic (3.44e-2)" "unprognostic (7.06e-3)" "unprognostic (1.78e-3)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (3.25e-2)" "unprognostic (1.41e-1)" "unprognostic (7.66e-3)" "prognostic favorable (8.28e-4)" "unprognostic (4.06e-2)" "unprognostic (4.55e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (8.71e-2)" "unprognostic (4.13e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" 8.3 5.3 7.8 7.7 7.6 9.4 8.3 7.4 9.3 9.5 6.8 12.4 4.3 8.6 7.6 6.9 8.8 5.8 7.7 7.8 6.9 11.7 4.8 8.1 8.4 7.1 7.3 7.6 11.1 8.1 6.5 8.5 7.3 9.7 5.8 8.5 6.3 8.4 7.5 7.5 8.2 8.0 6.7 12.6 7.9 10.5 7.7 8.4 10.8 8.1 8.8 9.9 8.3 7.9 7.6 5.8 12.0 31.9 20.4 16.4 49.6 8.6 11.4 11.7 12.5 8.7 12.5 10.1 11.1 7.9 21.5 14.9 4.5 37.6 17.8 13.7 13.8 3.1 8.0 1.1 15.4 0.0 8.3 12.9 22.9 10.3 20.8 15.1 11.3 13.5 2.5 0.0 17.2 15.4 15.5 10.2 10.5 7.0 15.0 11.6 2.1 6.5 10.9 7.6 13.1 14.3 10.9 12.3 17.0 15.7 10.1 14.9 8.8 13.2 8.6 7.5 7.4 3.3 7.2 6.3 0.5 2.3 16.9 4.5 6.0 15.6 4.9 4.0 6.1 5.4 4.3 5.5 5.4 3.5 4.8 3.6 15.8 6.1 4.1 2.0 4.4 3.6 7.8 7.6 7.4 9.3 7.8 6.9 7.1 7.3 7.3 6.7 7.7 7.9 10.7 12.8 7.4 8.8 7.5 5.0 11.7 14.1 4.0 9.0 8.2 9.3 6.6 4.3 11.3 7.3 14.6 12.8 12.6 3.7 13.7 11.3 18.8 5.9 9.0 9.0 4.8 7.8 18.6 7.6 14.6 9.5 3.6 5.7 6.3 14.3 4.6 1.5 8.9 6.7 10.9 2.7 8.2 7.7 8.2 4.7 6.8 8.2 10.6 10.3 7.6 9.2 16.5 12.5 13.3 7.2 1.4 10.5 3.2 10.7 4.1 17.0 9.5 10.5 6.6 10.1 9.4 36.2 12.0 4.8 5.5 12.2 9.2 10.9 4.3 7.7 ZNF548 FLJ32932 ENSG00000188785 "Zinc finger protein 548" Q8NEK5 19 57389850-57402992 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 55.6" HPA066042 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA066042: AB_2685602" "prognostic favorable (7.85e-4)" "unprognostic (4.61e-2)" "unprognostic (5.53e-2)" "unprognostic (8.52e-2)" "unprognostic (1.28e-1)" "unprognostic (4.05e-3)" "unprognostic (1.61e-2)" "unprognostic (6.77e-2)" "unprognostic (3.01e-2)" "unprognostic (1.59e-2)" "unprognostic (4.66e-2)" "unprognostic (2.50e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.55e-1)" "unprognostic (3.86e-3)" "unprognostic (5.85e-2)" 13.8 6.8 5.2 16.9 5.4 26.3 12.3 11.6 11.2 8.2 6.6 10.0 6.8 10.8 6.9 8.1 10.2 11.3 11.1 7.2 5.5 6.5 6.8 12.0 23.8 4.8 5.0 11.8 6.9 8.6 7.1 8.4 4.5 7.8 8.2 12.6 7.1 7.1 7.6 10.3 14.6 11.6 3.6 18.9 7.2 6.5 5.3 13.4 11.8 5.5 17.9 8.4 7.7 7.2 7.5 6.8 12.1 8.7 5.7 6.2 2.5 5.4 8.0 8.4 14.0 1.7 20.5 7.4 3.4 4.3 5.6 3.3 5.1 5.9 7.6 3.5 17.4 7.7 55.6 8.8 4.1 8.1 16.3 7.2 8.5 8.0 11.7 8.1 4.2 15.1 0.5 0.1 7.6 2.0 12.8 3.1 3.4 0.2 7.6 15.6 13.3 10.1 4.4 12.7 7.5 9.1 6.6 3.5 4.0 10.2 7.6 6.1 6.9 10.0 9.7 3.3 9.8 18.7 13.1 10.3 6.9 4.5 10.1 1.3 1.5 2.6 4.0 1.7 5.6 3.9 3.7 5.2 3.1 8.4 5.5 5.8 1.4 5.1 2.2 2.6 7.0 2.6 5.2 5.4 11.6 11.2 7.2 5.5 4.8 5.0 4.5 3.6 5.3 7.2 10.2 3.2 6.7 4.6 9.5 6.6 4.9 4.3 4.6 5.0 9.1 7.1 5.7 7.2 4.0 7.3 6.2 4.4 8.9 1.9 3.9 4.4 12.7 5.3 4.4 9.1 6.0 1.7 3.0 2.4 2.9 5.9 2.0 4.5 9.5 7.6 11.0 8.4 4.2 1.7 3.9 3.8 4.1 4.8 2.9 5.1 5.6 4.3 0.0 1.9 3.2 6.3 8.2 4.0 4.6 2.5 1.1 4.1 8.8 3.5 3.3 2.7 5.8 9.4 0.0 7.7 7.8 11.7 7.1 4.5 5.7 4.4 9.4 4.2 2.3 2.2 ZNF746 "FLJ31413, PARIS" ENSG00000181220 "Zinc finger protein 746" Q6NUN9 7 149472696-149497817 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.0;neutrophil: 6.9" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020272 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 2: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "HPA020272: AB_2670398" "unprognostic (2.66e-1)" "unprognostic (4.94e-2)" "unprognostic (4.27e-3)" "unprognostic (1.80e-2)" "unprognostic (2.10e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (2.32e-5)" "unprognostic (2.07e-1)" "unprognostic (1.79e-1)" "unprognostic (3.33e-1)" "prognostic favorable (4.22e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (7.47e-6)" "unprognostic (2.21e-2)" "unprognostic (2.09e-1)" "unprognostic (2.10e-1)" "unprognostic (2.06e-1)" 7.9 8.1 8.2 6.4 7.8 21.5 7.4 8.2 9.6 8.9 4.6 8.2 4.1 8.9 3.6 7.0 8.5 4.1 6.5 10.0 7.7 7.0 9.5 8.5 7.1 9.7 6.8 7.9 7.9 6.0 10.6 5.7 9.3 8.5 3.0 4.8 6.8 3.9 6.4 8.4 7.8 4.3 5.8 15.8 7.4 16.2 7.9 7.4 7.5 4.1 4.5 8.6 7.4 6.9 9.4 14.7 7.6 21.0 8.5 7.3 11.6 9.4 7.6 7.3 6.3 9.4 6.9 13.4 13.3 8.2 10.7 10.1 10.0 10.6 4.4 17.0 14.0 6.5 7.7 13.2 10.3 12.7 16.7 8.1 12.7 6.0 6.6 6.6 7.7 10.8 20.2 10.0 9.4 14.3 29.1 17.2 18.9 5.8 10.1 19.1 7.1 11.8 7.1 11.1 10.8 14.9 12.4 13.5 8.9 4.5 6.3 15.6 10.9 9.2 3.3 16.0 13.9 18.5 9.4 10.7 12.1 10.1 16.6 2.0 0.7 0.8 0.4 0.4 0.4 0.2 0.6 1.0 0.4 0.3 0.7 0.5 6.9 0.4 0.4 0.6 1.1 0.3 8.2 7.8 8.2 9.6 10.0 7.7 9.7 6.8 9.3 5.8 7.9 6.9 6.4 0.0 7.2 8.8 7.6 3.6 5.2 2.6 4.6 15.4 5.4 4.2 7.1 4.3 4.1 11.0 4.2 7.0 11.0 4.3 0.0 3.5 10.9 4.3 8.8 5.7 6.0 17.2 13.8 2.4 6.9 6.6 9.7 4.4 6.3 6.2 5.0 7.4 8.3 26.9 12.8 4.3 4.1 14.2 4.0 16.0 6.2 7.7 3.6 7.5 9.1 7.6 8.2 6.0 8.2 4.1 3.1 6.8 4.9 6.6 2.3 4.2 4.3 11.1 0.0 8.0 5.5 18.3 9.7 6.0 3.4 8.8 8.4 10.1 3.9 5.3