Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065434-125143333 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 67.1;Excitatory neurons: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA058815: AB_2683826" "unprognostic (1.28e-1)" "unprognostic (9.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-3)" "unprognostic (6.60e-6)" "unprognostic (3.03e-2)" "unprognostic (3.32e-2)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" "unprognostic (3.04e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-2)" "unprognostic (6.80e-2)" 31.7 7.8 6.4 5.6 8.2 3.7 43.4 2.8 11.0 14.6 3.2 12.7 17.9 6.3 8.7 30.9 8.5 7.6 7.4 9.1 3.7 10.3 3.9 6.2 5.8 6.1 3.1 6.0 12.8 9.6 8.5 6.1 6.0 8.6 11.3 6.2 48.2 7.5 5.5 40.4 10.4 5.8 2.4 5.2 16.9 13.5 5.0 10.4 10.0 7.6 10.2 6.1 14.3 6.5 26.8 26.2 11.2 15.3 40.3 26.1 18.7 21.2 20.1 24.6 21.8 34.0 17.4 16.5 21.3 25.7 10.6 28.4 21.0 22.8 13.2 17.8 19.2 13.1 16.9 26.2 33.5 9.4 12.8 29.1 18.2 21.0 21.0 30.8 18.1 9.5 9.4 9.9 15.9 49.1 10.8 12.7 14.2 28.0 30.4 2.1 28.2 23.0 25.0 40.2 29.7 8.6 22.4 35.0 16.6 10.8 26.2 20.7 17.4 11.8 18.7 13.4 16.4 22.0 13.6 18.0 14.8 15.4 13.2 7.7 2.1 5.9 3.3 0.6 4.4 2.4 3.1 2.5 2.4 1.2 4.4 3.0 0.3 5.4 0.7 9.9 2.1 3.4 6.4 8.2 2.8 11.0 9.1 3.7 6.1 3.1 6.0 2.4 5.0 6.5 4.2 6.4 17.3 16.3 4.5 16.6 5.6 14.1 9.1 20.9 23.6 16.9 9.4 17.2 12.0 5.5 27.1 2.1 6.5 14.0 7.9 11.0 67.1 6.3 15.3 6.5 25.2 0.8 59.4 10.7 8.7 11.8 13.3 12.3 2.5 13.1 2.2 4.2 4.8 6.7 28.6 22.0 16.2 4.1 9.0 22.5 9.3 3.9 5.4 5.6 5.4 5.6 5.2 12.1 12.5 9.9 7.4 5.3 12.1 8.2 10.7 6.5 5.7 21.8 0.0 8.6 7.7 22.0 5.3 25.3 28.1 2.5 8.1 20.8 15.8 5.6 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 67.8;neutrophil: 42.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favorable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favorable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 38.8 12.5 6.7 8.5 8.6 39.6 27.9 10.5 8.9 9.8 6.0 12.3 9.9 5.7 4.1 31.1 5.1 11.6 13.4 6.8 7.4 12.0 21.7 16.4 3.4 9.2 8.2 4.6 16.0 12.2 5.6 10.2 9.1 7.1 7.5 6.3 27.4 8.4 15.0 38.0 10.5 9.3 9.3 9.4 12.1 10.8 8.4 6.8 15.5 18.5 7.9 16.7 16.9 11.9 18.9 6.8 8.2 9.7 32.0 12.8 17.1 77.4 27.1 18.8 14.9 9.4 6.4 16.2 10.9 23.2 15.8 5.8 16.5 18.5 22.6 58.4 13.2 36.6 24.4 7.5 15.7 9.2 13.2 13.0 64.6 31.3 28.5 18.8 33.3 10.8 23.9 14.2 46.9 11.0 7.6 6.9 22.8 16.7 20.4 3.1 24.1 8.6 27.9 40.4 10.6 13.6 36.9 20.5 9.8 9.8 18.9 8.9 19.3 18.1 13.6 35.0 34.5 11.1 34.0 7.7 20.3 17.3 16.0 67.8 14.7 9.5 2.3 7.9 1.7 3.5 1.7 2.7 6.8 4.0 1.6 2.5 42.5 2.0 5.7 1.9 4.8 5.3 6.7 8.6 10.5 8.9 6.8 7.4 9.2 8.2 9.1 9.3 8.4 11.9 117.5 25.6 51.8 12.7 44.8 39.9 27.5 25.9 88.8 11.9 149.9 116.2 10.3 14.3 49.6 27.6 27.1 16.7 80.3 65.0 33.2 57.5 19.5 47.5 49.0 34.6 36.2 69.0 24.1 61.5 24.9 53.7 67.8 114.0 16.5 8.8 18.2 12.7 18.0 3.3 24.1 23.7 34.6 44.1 17.4 17.1 5.3 79.8 7.2 11.2 35.9 11.0 12.3 18.1 28.8 75.2 49.8 5.7 41.8 25.5 98.5 39.8 19.1 17.4 0.0 32.0 46.4 47.3 41.9 111.7 40.9 205.4 42.6 15.2 21.9 71.6 AC135050.2 ENSG00000255439 "Novel protein, VKORC1 and PRSS53 readthrough" 16 31083439-31094956 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 5.2;NB-4: 6.8;RPMI-8226: 8.7;U-266/70: 5.7" HPA042720 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (6.94e-2)" "unprognostic (2.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.68e-3)" "unprognostic (2.45e-3)" "unprognostic (1.34e-1)" "unprognostic (3.57e-1)" "unprognostic (2.79e-2)" "unprognostic (4.48e-3)" "unprognostic (8.49e-2)" "unprognostic (2.84e-8)" "unprognostic (4.96e-6)" "unprognostic (1.39e-1)" "unprognostic (4.81e-1)" "unprognostic (2.29e-4)" 0.4 0.1 0.0 0.3 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.7 0.1 0.3 0.1 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.7 0.2 0.2 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 1.1 0.4 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.3 0.1 0.9 0.4 0.0 0.4 1.0 1.2 0.3 5.2 0.3 0.0 0.2 0.2 0.3 3.4 1.8 0.1 0.0 0.2 0.0 0.1 0.0 1.3 2.7 0.8 0.3 0.2 0.0 0.5 1.1 0.3 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.7 0.1 0.4 0.8 6.8 0.1 0.0 1.5 3.4 0.3 8.7 0.0 0.3 2.1 2.6 1.2 0.4 1.0 0.0 0.0 0.2 1.3 0.5 0.0 1.6 0.5 5.7 0.7 0.6 1.2 0.9 0.2 0.6 0.7 2.5 2.0 0.8 2.7 2.1 2.1 2.8 0.9 1.6 1.3 1.9 0.9 0.9 1.8 1.6 2.8 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Fibroblasts: 21.4;Proximal enterocytes: 19.1;Respiratory ciliated cells: 15.7" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "BJ hTERT+: 285.1" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" 11.1 1.4 0.6 1.0 0.2 0.8 5.5 0.3 0.3 0.7 0.9 1.9 15.8 3.7 1.7 1.4 2.0 6.5 5.7 0.4 0.0 1.1 1.0 8.0 2.1 0.3 0.5 1.0 2.6 0.0 6.7 0.2 0.3 0.5 1.3 0.6 7.1 1.9 0.5 8.9 13.0 2.2 0.3 1.6 10.2 0.4 0.1 0.5 1.4 1.0 1.6 4.6 1.1 0.2 0.2 0.0 0.2 0.2 19.9 10.7 0.1 47.7 285.1 2.8 7.9 0.2 0.4 3.3 0.0 29.9 0.2 0.1 0.0 0.0 1.8 1.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 1.3 0.0 0.0 4.9 0.1 0.2 0.6 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.1 0.1 0.2 0.0 0.5 0.1 0.7 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.3 0.4 0.0 0.3 0.5 0.3 0.3 0.1 0.2 1.6 38.5 1.1 0.7 0.1 6.5 0.6 1.3 0.0 1.6 0.3 0.3 0.7 1.5 2.3 5.5 6.2 0.2 0.1 1.1 0.0 0.2 2.9 2.9 0.6 3.9 0.0 0.0 0.6 12.1 0.1 21.4 10.7 0.6 0.0 0.7 9.7 0.2 0.4 1.7 0.5 0.8 0.0 0.3 5.1 0.4 2.1 0.3 1.8 1.9 6.8 0.9 0.0 0.0 0.3 5.1 0.1 2.6 0.5 0.4 19.1 3.0 15.7 3.4 0.0 1.3 2.6 0.1 0.1 0.6 6.5 0.3 0.5 12.5 3.7 1.2 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Inhibitory neurons: 63.4;Oligodendrocyte precursor cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 26.3;RH-30: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 7.3 4.0 6.2 4.6 7.4 3.3 7.0 10.8 6.4 5.4 1.0 6.3 7.7 5.2 6.6 7.2 4.5 7.7 3.7 7.5 7.5 5.6 7.4 4.6 3.1 2.6 4.5 4.5 4.4 4.3 3.9 7.7 3.9 6.8 6.5 8.3 7.5 5.2 17.5 19.5 9.3 7.0 3.8 4.0 6.8 6.4 8.6 2.3 6.7 6.3 3.9 7.4 7.4 4.6 1.8 2.1 13.2 5.0 7.3 4.7 5.4 4.1 5.0 6.9 12.0 5.8 8.1 0.1 3.6 6.7 2.5 6.2 12.0 6.1 8.8 1.4 7.3 0.9 3.6 10.2 26.3 1.0 0.9 8.1 7.3 4.5 8.9 5.2 5.3 1.6 2.0 3.5 4.7 4.8 0.4 0.8 14.9 5.5 3.6 0.2 23.3 1.3 5.6 11.5 13.0 7.3 3.5 4.2 5.4 5.6 2.5 1.4 4.1 6.4 7.5 6.1 2.9 1.0 0.3 2.4 3.9 0.5 5.2 0.2 1.7 0.2 0.6 2.0 0.2 0.1 2.4 1.1 1.3 0.3 1.5 0.3 0.0 4.8 2.0 1.7 0.2 0.7 6.2 7.4 10.8 6.4 7.5 7.5 2.6 4.5 3.9 3.8 8.6 4.6 13.7 6.4 7.0 26.8 1.5 29.7 6.9 9.5 13.1 15.4 6.8 12.4 7.9 17.2 10.7 7.3 14.6 4.9 6.0 16.5 1.9 6.3 5.3 6.4 12.2 11.9 9.0 0.0 62.5 6.3 2.5 17.4 6.6 5.7 0.0 2.2 11.7 12.1 5.4 11.8 63.4 12.9 8.2 7.3 18.9 2.1 9.9 5.7 10.6 33.7 7.2 3.3 6.2 84.9 34.1 7.6 10.0 11.3 5.2 7.7 23.7 5.8 10.2 9.4 32.9 8.3 10.9 18.2 14.1 14.4 29.8 5.3 5.9 2.9 11.7 11.8 ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.5;Extravillous trophoblasts: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Cell line enhanced" "Detected in many" "PC-3: 329.5;RPMI-8226: 361.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" 70.1 18.5 12.5 21.4 16.0 34.1 64.7 16.9 13.9 40.3 7.1 38.3 16.4 42.5 7.6 79.1 41.5 21.6 63.1 10.5 13.8 32.4 15.1 50.0 10.0 20.2 15.1 25.5 25.5 30.0 14.1 39.1 16.8 40.0 23.8 3.4 45.3 16.7 22.7 107.9 31.3 38.6 17.3 28.8 44.2 4.9 17.1 7.3 31.6 32.4 13.6 38.9 57.3 18.0 112.0 35.0 7.0 153.2 54.9 45.6 66.3 48.2 60.9 60.1 40.5 25.9 63.3 30.9 210.7 63.5 26.7 135.9 34.5 147.9 15.8 14.3 44.9 7.6 63.1 25.3 95.5 63.4 7.9 48.7 153.8 60.5 86.6 82.6 274.7 9.3 11.9 124.8 45.2 64.7 0.5 47.1 21.6 193.4 329.5 10.0 20.5 361.8 43.7 29.7 20.8 44.7 105.2 131.2 41.8 10.7 194.8 38.9 205.1 58.6 24.6 58.9 54.1 13.9 11.7 13.7 42.7 47.6 65.4 0.0 39.1 0.8 9.5 26.5 6.5 2.0 4.7 5.6 64.0 2.1 2.0 2.5 1.4 1.6 6.2 5.3 8.9 22.8 12.5 16.0 16.9 13.9 10.5 13.8 20.2 15.1 16.8 17.3 17.1 18.0 164.5 3.2 6.7 8.8 6.6 48.9 30.4 81.6 47.8 9.7 34.6 20.7 11.5 35.8 38.3 9.2 29.2 13.0 8.1 100.4 0.0 33.4 1.7 13.3 9.2 120.8 12.7 4.6 8.1 25.5 172.4 19.8 85.6 15.4 1.3 8.5 62.2 19.9 31.7 6.7 9.8 80.7 18.3 65.0 43.6 1.3 17.4 27.2 14.2 15.9 28.8 8.8 13.4 9.0 16.8 42.1 50.9 18.0 8.0 55.2 47.4 2.6 22.9 17.0 13.1 15.7 14.5 0.8 6.4 91.2 57.1 17.8 8.6 2.7 76.9 40.0 ADGRF2 "GPR111, hGPCR35, PGR20" ENSG00000164393 "Adhesion G protein-coupled receptor F2" Q8IZF7 6 47656436-47697797 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.0;skin 1: 2.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Early spermatids: 1.0;Endometrial ciliated cells: 1.6;Excitatory neurons: 1.2;Glandular and luminal cells: 1.3;Squamous epithelial cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035507 Uncertain NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: Endometrium - Transcription" "HPA035507: AB_10601809" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (3.74e-2)" "unprognostic (5.95e-1)" "unprognostic (1.59e-1)" "unprognostic (1.53e-1)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (2.51e-4)" "unprognostic (3.05e-2)" "unprognostic (3.86e-2)" "unprognostic (1.20e-1)" "unprognostic (2.24e-1)" "unprognostic (7.99e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.6 0.1 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.3;skin 1: 38.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Pancreatic endocrine cells: 20.5;Prostatic glandular cells: 6.0;Squamous epithelial cells: 14.4;Syncytiotrophoblasts: 7.3;Urothelial cells: 20.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.2" "Region enriched" "Detected in single" 5 "hypothalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 13.2;HBEC3-KT: 21.0;hTCEpi: 31.8;OE19: 18.4;U-87 MG: 26.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" 0.2 0.7 0.0 0.2 0.0 0.0 2.2 0.4 0.1 4.7 0.0 1.2 0.0 0.3 0.0 18.3 1.1 0.7 0.6 0.0 1.9 0.7 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 2.0 0.0 0.2 1.5 0.0 2.4 0.0 0.6 38.8 0.2 0.1 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.9 4.1 4.3 9.6 0.0 8.9 1.2 0.0 0.0 0.0 0.0 1.0 0.0 5.1 0.1 0.0 2.4 0.0 0.0 0.0 0.0 8.2 13.2 0.0 21.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 31.8 0.4 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 18.4 1.2 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.4 1.8 0.1 0.2 0.0 0.0 0.0 0.8 0.1 1.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 4.4 0.0 3.5 0.7 1.6 0.3 0.2 0.0 0.0 0.6 3.4 15.1 0.4 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.5 0.0 0.0 6.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 14.4 0.0 7.3 0.0 0.0 0.1 20.5 ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 196.1;Basal keratinocytes: 387.5;Basal respiratory cells: 146.6;Squamous epithelial cells: 276.0;Suprabasal keratinocytes: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 72.4;hTERT-HME1: 74.1;PC-3: 31.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003431, HPA075322" Uncertain Uncertain Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA003431: AB_1845333, HPA075322: " "unprognostic (2.28e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-3)" "unprognostic (5.54e-2)" "unprognostic (2.34e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (3.15e-9)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" 19.5 1.6 4.5 3.2 4.7 12.5 18.7 5.1 4.4 13.5 1.8 2.3 1.9 2.3 1.7 15.1 4.1 3.8 6.7 5.3 4.2 1.1 14.2 19.5 4.1 6.0 5.6 0.9 1.2 2.2 0.3 9.9 6.2 9.0 2.8 0.6 4.2 1.5 11.7 21.8 2.1 3.7 6.2 7.9 7.5 0.5 7.1 2.7 1.0 8.6 6.0 6.8 7.2 7.6 23.3 0.1 0.1 0.0 0.8 0.2 0.0 4.3 13.2 6.0 6.7 0.0 9.7 0.1 6.1 1.3 21.5 20.0 0.0 27.9 6.9 0.0 0.6 0.0 5.1 0.0 0.6 0.1 11.0 0.1 72.4 2.0 74.1 5.0 2.8 0.0 0.1 8.3 16.0 0.0 0.0 12.9 0.4 0.2 31.2 6.7 4.1 13.0 3.2 5.8 0.1 0.1 5.4 0.4 2.0 2.5 0.0 7.0 12.3 0.0 5.0 7.2 3.5 1.9 0.0 0.2 0.0 15.1 2.6 16.5 21.8 67.8 151.4 37.1 112.3 21.5 34.3 93.0 24.7 15.6 5.8 53.3 35.4 37.2 53.3 28.4 2.3 53.4 4.5 4.7 5.1 4.4 5.3 4.2 6.0 5.6 6.2 6.2 7.1 7.6 196.1 112.2 31.6 1.6 16.5 387.5 36.6 146.6 127.5 0.5 23.3 15.2 18.6 0.0 67.4 0.0 0.0 0.4 59.2 3.7 0.0 2.4 0.5 3.2 0.5 40.3 3.0 1.3 0.0 0.2 0.3 6.2 35.7 3.0 118.6 0.1 6.8 14.1 17.7 0.0 0.0 3.1 16.2 20.8 54.9 0.7 0.0 21.1 30.2 15.9 4.0 4.1 90.6 0.0 0.1 8.6 0.1 0.0 23.2 23.5 0.1 0.1 27.8 5.0 0.0 19.8 9.6 0.7 0.1 276.0 245.4 0.5 40.1 0.1 3.5 61.5 AHNAK MGC5395 ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 561.4;fHDF/TERT166: 554.5;TIME: 582.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 395.4" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 10000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA019010: AB_1844657, HPA019070: AB_1844656, HPA026643: AB_10670426" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (3.46e-1)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.84e-2)" "unprognostic (1.98e-3)" "prognostic unfavorable (2.42e-4)" "unprognostic (4.30e-1)" "unprognostic (4.49e-3)" "unprognostic (5.42e-2)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.47e-6)" 243.1 27.9 62.6 43.4 50.2 44.1 190.3 33.7 45.4 183.3 61.0 276.2 49.0 183.3 51.7 248.2 145.5 74.8 115.1 65.0 98.0 59.7 60.1 144.1 36.7 76.2 48.3 125.8 30.3 26.3 16.9 97.3 62.9 88.5 96.6 10.1 127.5 105.7 188.5 334.7 136.6 113.1 60.8 59.5 133.5 18.0 49.0 27.9 64.9 172.2 63.7 142.0 213.3 78.4 188.2 107.9 9.8 44.1 421.8 561.4 70.3 166.0 201.4 103.0 57.4 93.7 64.9 0.2 61.7 554.5 79.8 244.1 41.2 203.7 130.7 154.2 7.3 22.6 173.4 27.9 80.8 31.5 142.2 204.2 233.0 202.4 183.6 131.5 215.4 2.7 21.8 138.8 211.7 72.1 0.4 60.7 3.0 59.6 171.7 0.4 45.1 113.9 227.1 120.2 0.3 9.2 167.5 69.3 69.0 198.8 133.7 28.4 582.1 182.4 119.8 229.8 74.4 25.0 5.4 0.6 138.2 10.1 60.9 44.1 75.6 0.3 38.7 45.0 25.8 20.0 24.8 31.7 73.8 16.1 3.2 17.3 1.1 31.5 37.8 20.2 21.5 36.8 62.6 50.2 33.7 45.4 65.0 98.0 76.2 48.3 62.9 60.8 49.0 78.4 413.1 439.1 106.3 49.3 171.4 479.4 133.8 285.0 253.2 1.4 173.0 226.8 199.9 195.9 224.1 193.1 0.0 110.8 194.3 400.8 13.7 99.6 10.6 188.5 195.0 282.5 47.6 43.7 0.9 64.1 145.6 312.9 538.2 351.2 238.9 4.3 201.4 88.5 79.4 1.7 0.8 164.8 138.4 329.8 458.3 33.2 451.4 292.3 318.4 43.1 284.8 30.7 138.0 0.5 0.4 262.5 195.5 466.0 329.0 202.4 262.3 6.8 149.3 1.2 177.5 349.5 244.4 3.1 8.1 596.4 610.3 102.2 256.5 3.0 101.8 198.0 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.3;Basal respiratory cells: 83.8;Horizontal cells: 60.6;Ionocytes: 61.1;Pancreatic endocrine cells: 68.2;Respiratory ciliated cells: 66.8;Squamous epithelial cells: 63.7;Suprabasal keratinocytes: 164.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 135.1;HBEC3-KT: 124.9;hTCEpi: 308.7;hTERT-HME1: 130.3;TIME: 138.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" 30.4 2.3 9.8 2.4 9.9 0.0 16.4 9.3 15.9 84.5 4.6 105.3 1.4 64.3 2.9 114.1 29.2 5.1 4.5 9.7 16.0 3.5 6.2 5.1 0.1 38.1 15.3 3.5 1.6 0.7 3.4 1.8 40.8 18.6 8.6 19.0 24.0 28.6 3.6 305.9 20.2 31.6 12.4 0.9 25.2 7.7 18.1 0.4 2.8 4.5 4.7 49.4 86.6 18.5 2.9 107.6 0.1 6.0 120.0 135.1 0.2 10.5 22.3 3.8 1.9 0.3 38.9 0.1 14.5 82.9 85.3 62.9 0.3 124.9 1.7 0.0 0.4 0.0 67.5 0.5 11.0 0.0 3.8 17.6 308.7 12.1 130.3 52.3 54.7 0.0 0.0 0.2 62.8 8.0 0.0 0.0 0.3 9.5 42.9 0.3 5.7 0.1 84.4 0.0 0.6 0.6 46.2 0.1 2.3 2.8 6.0 0.0 138.4 29.3 17.9 33.8 9.9 0.0 0.0 0.0 88.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.8 9.9 9.3 15.9 9.7 16.0 38.1 15.3 40.8 12.4 18.1 18.5 3.8 12.8 1.1 0.3 0.0 114.3 4.9 83.8 13.1 8.9 2.2 1.3 1.5 0.0 38.2 1.8 2.1 0.2 0.3 0.4 0.0 11.9 24.2 16.0 10.5 13.0 0.0 0.0 8.2 8.7 0.5 31.9 0.0 18.9 17.1 0.1 3.6 2.1 1.0 60.6 5.1 0.0 61.1 0.3 12.7 3.1 0.6 0.7 32.0 3.7 0.0 3.2 0.0 1.5 3.3 68.2 0.0 0.4 0.0 4.5 0.0 0.3 66.8 13.9 0.0 13.1 8.6 0.4 4.3 63.7 164.7 0.1 0.9 0.1 0.2 6.2 AJUBA "JUB, MGC15563" ENSG00000129474 "Ajuba LIM protein" Q96IF1 14 22971177-22982551 "Cancer-related genes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 61.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 47.5;Basal squamous epithelial cells: 35.3;Pancreatic endocrine cells: 33.8;Prostatic glandular cells: 34.2;Sertoli cells: 32.9;Suprabasal keratinocytes: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 217.0;hTCEpi: 222.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006171 Approved Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Golgi apparatus" "HPA006171: AB_1852044" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (2.39e-1)" "unprognostic (1.24e-3)" "unprognostic (9.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-3)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.47e-1)" "unprognostic (3.19e-3)" "unprognostic (2.94e-1)" "unprognostic (2.68e-1)" "unprognostic (9.35e-3)" "unprognostic (2.07e-1)" 4.8 3.0 2.3 1.4 1.8 0.5 6.7 2.0 2.2 14.4 9.2 3.2 1.5 12.1 8.5 18.3 7.5 4.9 6.3 2.2 1.5 17.7 43.4 15.2 2.6 2.5 2.1 12.2 11.6 7.2 2.0 19.3 1.6 10.6 2.5 3.7 8.2 15.9 1.9 61.7 1.9 8.4 2.2 3.8 4.2 5.5 1.9 8.2 10.9 2.3 5.5 7.6 15.5 2.7 46.9 54.1 71.0 27.6 6.8 12.2 57.4 44.9 58.5 102.6 91.4 116.0 47.3 1.2 45.5 92.9 70.8 146.2 54.9 217.0 124.6 4.5 5.0 3.5 90.8 131.4 78.9 4.9 3.1 38.9 222.3 42.9 164.3 72.7 40.0 8.3 1.9 2.8 96.2 37.3 4.5 5.7 4.5 86.6 73.9 12.7 59.0 1.2 103.9 71.3 0.2 6.2 135.5 39.4 8.8 57.4 55.3 4.5 36.1 44.2 88.4 7.3 43.6 0.4 1.3 0.5 7.0 4.2 20.6 0.7 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.2 0.5 0.5 0.2 0.2 0.0 0.1 2.3 1.8 2.0 2.2 2.2 1.5 2.5 2.1 1.6 2.2 1.9 2.7 2.1 19.2 6.4 0.7 0.0 47.5 13.0 27.6 35.3 0.1 3.7 9.7 4.5 20.0 10.2 7.3 0.0 10.0 0.1 0.3 5.9 14.3 5.8 13.0 2.5 4.0 0.0 0.0 0.0 14.9 9.8 3.4 0.0 4.4 0.0 12.8 2.5 17.1 1.7 0.0 0.0 0.4 2.0 0.0 2.2 5.0 3.7 0.6 3.6 0.0 0.0 8.1 0.0 0.5 0.0 33.8 0.1 0.7 1.2 34.2 0.3 21.0 8.3 0.2 32.9 2.7 14.0 7.0 2.7 14.2 49.6 4.0 0.5 1.6 0.8 18.0 ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 90.2" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.7;Rod photoreceptor cells: 1.2;Spermatogonia: 1.2;Suprabasal keratinocytes: 1.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Cell line enhanced" "Detected in some" "A549: 1.1;HEK 293: 1.3;hTCEpi: 1.6;JURKAT: 2.7;OE19: 1.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 7000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Cytosol Vesicles "HPA024002: AB_1844757" "unprognostic (1.27e-2)" "unprognostic (1.59e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-2)" "unprognostic (3.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (4.40e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (3.46e-2)" 0.0 0.0 0.4 0.1 0.5 0.1 2.1 0.4 0.6 5.7 0.0 0.1 0.3 0.0 0.0 5.6 0.2 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.5 0.4 0.2 0.0 0.2 1.2 0.1 0.0 0.5 0.4 0.1 0.6 0.8 0.0 0.4 90.2 0.2 0.0 0.1 0.2 0.2 0.2 0.4 0.6 0.0 0.0 19.1 0.0 15.0 0.1 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.3 0.0 0.0 0.0 1.3 0.0 0.4 0.1 0.0 0.2 0.0 0.0 1.6 0.1 0.5 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.8 0.0 0.9 0.0 0.4 0.4 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.4 0.6 0.1 0.2 0.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.5 0.4 0.6 0.4 0.2 0.4 0.2 0.5 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.8 1.2 0.0 1.8 0.0 0.0 0.0 0.1 0.1 ANXA8L1 "ANXA8L2, bA145E20.2, bA301J7.3" ENSG00000264230 "Annexin A8 like 1" Q5VT79 10 46375627-46391784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 195.2;skin 1: 325.4;vagina: 100.5" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 118.7" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2;head and neck cancer: 5.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 374.5;HBEC3-KT: 485.0;hTCEpi: 140.1;SiHa: 116.6" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (3.67e-3)" "unprognostic (4.56e-3)" "unprognostic (9.14e-3)" "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-2)" "unprognostic (8.05e-2)" "unprognostic (6.94e-3)" "unprognostic (8.33e-5)" "unprognostic (3.43e-1)" "unprognostic (8.26e-10)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" 39.8 0.2 0.0 0.0 0.0 1.2 21.9 0.0 0.1 45.2 0.0 0.3 0.0 0.1 0.0 195.2 6.1 0.1 2.9 0.0 0.0 0.0 1.1 16.5 0.0 0.0 0.0 0.9 0.3 0.0 0.2 24.1 0.0 6.8 0.0 0.0 40.8 4.5 1.1 325.4 0.1 0.0 0.0 0.1 0.3 0.8 0.0 4.3 0.1 0.0 35.1 37.4 100.5 0.0 70.1 18.2 0.0 0.0 0.0 0.0 24.8 0.9 0.1 0.0 0.0 1.9 12.6 0.0 0.6 0.3 0.5 374.5 0.0 485.0 0.0 28.9 0.0 0.0 33.3 0.0 9.3 0.0 0.7 0.0 140.1 0.2 58.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 70.2 0.2 0.7 0.0 0.0 0.8 0.0 0.0 76.0 0.1 0.0 116.6 12.0 0.0 7.2 0.0 0.7 0.0 0.1 12.2 0.1 0.3 0.0 0.1 0.0 2.8 0.1 0.2 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.9 1.1 0.0 0.0 0.0 3.0 0.2 11.4 1.6 2.3 2.4 3.7 18.6 19.9 0.0 0.0 14.8 0.0 3.0 0.0 0.7 0.4 1.0 0.0 0.9 0.0 0.0 0.0 0.2 11.4 12.8 5.6 0.1 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.7 1.4 0.0 1.2 2.5 5.2 0.0 10.9 0.2 13.1 0.0 1.5 0.3 2.4 118.7 1.1 6.3 0.6 0.0 0.2 5.9 ARHGEF19 "FLJ33962, WGEF" ENSG00000142632 "Rho guanine nucleotide exchange factor 19" Q8IW93 1 16197854-16212652 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 17.6;HaCaT: 14.4;T-47d: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068108 Approved "Nuclear bodies" No No "Cluster 22: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 33: Fibroblasts - ECM organization" "Nuclear bodies" "HPA068108: AB_2685956" "unprognostic (2.19e-2)" "unprognostic (1.85e-3)" "unprognostic (1.33e-1)" "unprognostic (3.52e-2)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (9.45e-2)" "prognostic favorable (6.53e-4)" "unprognostic (4.01e-2)" "unprognostic (2.43e-2)" "unprognostic (2.07e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (8.88e-5)" "unprognostic (3.72e-2)" "unprognostic (2.84e-1)" "unprognostic (1.26e-1)" "unprognostic (1.80e-1)" 2.9 10.1 0.9 2.7 0.7 0.9 5.0 0.7 1.3 8.7 0.8 2.8 2.3 6.0 1.1 15.9 6.4 2.1 2.2 0.7 0.9 4.2 1.5 3.2 1.6 0.9 0.8 6.9 7.9 2.1 1.8 3.1 0.7 8.4 0.9 0.2 17.2 4.5 0.8 26.3 3.0 1.5 0.7 2.8 6.2 1.5 0.8 1.8 12.0 0.4 2.3 6.1 11.4 0.7 17.6 4.6 2.4 4.9 0.3 1.4 0.9 4.3 4.1 2.4 3.3 6.9 2.7 0.0 3.4 3.9 1.8 14.4 1.0 1.6 0.6 2.9 0.4 1.4 11.7 0.5 5.7 0.8 5.6 4.4 0.9 6.3 1.8 0.5 0.7 5.5 3.2 3.8 1.0 3.7 2.0 2.0 0.7 2.5 4.9 6.8 2.2 4.1 0.9 1.3 1.7 2.9 3.3 2.0 0.8 0.2 25.7 2.9 1.8 0.0 7.6 3.9 0.0 4.1 6.7 1.0 0.0 4.3 6.6 0.0 0.5 0.4 0.9 0.2 0.9 0.7 0.8 0.7 0.6 0.5 0.8 0.4 0.0 0.8 0.0 0.6 0.5 0.5 0.9 0.7 0.7 1.3 0.7 0.9 0.9 0.8 0.7 0.7 0.8 0.7 6.1 6.4 6.0 1.3 3.9 4.7 9.3 8.8 14.2 0.5 8.6 8.0 0.5 2.8 8.8 0.0 0.0 1.7 6.5 3.8 0.0 5.7 0.2 7.0 4.5 4.6 0.0 4.2 0.0 5.7 4.9 4.5 3.6 7.8 9.5 2.1 7.5 1.0 2.6 0.0 0.1 5.2 8.2 4.4 1.4 0.0 7.8 1.9 3.6 2.8 2.4 5.3 7.2 1.0 0.0 4.7 5.2 3.4 3.1 2.3 2.5 1.6 4.0 0.3 0.0 4.7 3.9 1.8 6.8 10.7 7.7 1.2 5.4 3.0 4.7 6.4 ARHGEF5 "GEF5, P60, TIM, TIM1" ENSG00000050327 "Rho guanine nucleotide exchange factor 5" Q12774 7 144355288-144380632 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 47.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 61.7;Glandular and luminal cells: 47.4;Paneth cells: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 29.4;CAPAN-2: 21.9;HaCaT: 16.7;hTCEpi: 18.0;RPTEC TERT1: 17.5;WM-115: 17.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA020980, HPA029504, HPA044188, HPA045619, HPA045699" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA020980: AB_1845007, HPA029504: AB_10602231, HPA044188: AB_2678850, HPA045619: AB_2679393, HPA045699: AB_2679423" "unprognostic (1.45e-1)" "unprognostic (2.05e-1)" "unprognostic (1.87e-2)" "unprognostic (1.94e-1)" "unprognostic (9.45e-2)" "unprognostic (2.69e-2)" "unprognostic (9.95e-3)" "unprognostic (9.21e-2)" "unprognostic (1.05e-2)" "unprognostic (2.27e-1)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "prognostic favorable (3.28e-7)" "unprognostic (4.67e-2)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "unprognostic (7.76e-2)" 5.1 2.6 1.8 1.6 2.4 2.4 12.3 1.5 1.7 11.5 5.7 16.4 10.1 3.4 6.9 36.6 4.7 4.7 3.5 0.9 1.8 20.9 14.4 8.4 2.2 2.1 2.7 5.6 19.0 7.3 9.5 3.2 1.8 14.7 5.6 1.8 18.1 2.0 0.7 47.1 13.1 1.2 1.3 3.8 13.8 2.0 2.0 1.8 24.0 0.2 3.1 5.3 17.6 1.4 29.4 3.3 0.0 0.0 0.0 0.0 8.7 3.8 2.3 1.5 1.9 11.5 21.9 0.1 10.3 0.9 0.3 16.7 0.0 10.6 1.5 0.1 3.8 0.0 4.2 0.8 3.1 0.0 0.0 5.5 18.0 0.7 9.9 4.8 0.1 0.0 0.0 0.0 1.5 9.7 0.1 0.0 4.5 7.9 5.2 1.1 0.0 0.4 17.5 1.3 0.1 0.1 11.5 13.4 5.1 2.3 6.8 0.3 0.2 0.5 0.8 0.0 0.1 0.0 0.1 0.1 0.6 0.0 17.7 0.0 0.0 0.0 0.3 0.0 0.4 0.8 0.8 0.7 0.0 0.9 0.9 0.2 0.3 0.0 0.0 0.0 1.5 0.1 1.8 2.4 1.5 1.7 0.9 1.8 2.1 2.7 1.8 1.3 2.0 1.4 3.0 6.4 14.8 0.3 2.3 18.5 37.3 9.4 26.2 0.0 17.5 18.7 1.4 11.5 12.1 22.0 4.2 11.8 1.4 61.7 5.9 14.8 2.3 28.9 5.5 1.6 9.6 2.7 0.0 16.5 15.2 3.6 37.2 47.4 0.0 4.0 1.8 7.5 1.8 0.0 0.0 24.0 6.1 0.3 1.9 0.6 1.5 1.2 5.4 0.0 0.0 2.7 0.0 0.5 0.1 27.7 53.7 1.5 3.1 14.3 42.0 5.4 13.5 3.1 0.0 1.1 1.8 0.7 1.5 28.7 16.8 14.2 2.5 1.1 23.5 33.6 ASCL2 "ASH2, bHLHa45, HASH2" ENSG00000183734 "Achaete-scute family bHLH transcription factor 2" Q99929 11 2268498-2270588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.9;salivary gland: 8.0;skin 1: 7.3" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 1042.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 76.1;stomach cancer: 23.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 7.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "BEWO: 25.1;NB-4: 8.1;OE19: 14.2;SCLC-21H: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (2.71e-3)" "prognostic favorable (5.11e-4)" "unprognostic (2.03e-1)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (2.69e-2)" "unprognostic (2.93e-2)" "unprognostic (7.88e-2)" "unprognostic (3.79e-2)" "unprognostic (1.22e-2)" "prognostic favorable (4.73e-4)" "unprognostic (5.85e-2)" "unprognostic (1.45e-6)" "unprognostic (8.86e-3)" "unprognostic (5.48e-2)" "unprognostic (6.12e-4)" "unprognostic (1.07e-3)" 0.3 0.2 1.0 1.2 0.6 0.8 0.7 0.5 0.9 2.4 0.4 3.9 6.9 2.2 0.5 1.6 0.4 0.1 0.1 0.9 0.5 1.7 0.8 0.6 0.7 1.7 2.0 0.1 0.7 0.1 0.1 5.5 1.0 2.3 2.5 0.0 8.0 1.6 0.2 7.3 5.5 0.1 1.1 2.3 2.1 0.8 1.4 0.5 0.5 0.0 0.6 1.5 1.9 2.3 0.0 0.0 0.4 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.7 0.0 8.1 0.6 14.2 0.0 0.0 0.0 0.0 0.0 0.6 20.5 0.1 0.0 0.5 0.0 0.0 2.5 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.9 1.2 7.9 2.2 1.7 0.1 0.0 0.5 1.3 0.8 0.0 0.1 1.3 0.9 0.0 1.4 0.0 0.0 0.4 1.0 0.6 0.5 0.9 0.9 0.5 1.7 2.0 1.0 1.1 1.4 2.3 1.2 0.0 0.0 0.0 1.4 13.6 14.1 3.3 23.3 0.0 7.2 3.3 0.9 1.5 0.7 20.2 0.0 18.7 29.2 14.4 7.9 0.2 0.1 1.4 4.7 2.6 78.2 4.4 0.0 0.0 1042.9 1.5 10.2 3.5 0.0 0.0 23.2 0.5 31.1 0.0 0.0 31.4 2.0 22.0 7.0 0.2 1.8 14.3 1.8 3.7 22.6 0.0 110.2 0.0 0.0 0.0 3.6 1.5 1.3 6.5 9.1 0.4 1.0 0.1 0.0 0.1 0.3 0.3 13.7 9.1 4.7 23.3 8.9 0.1 112.1 9.4 ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 8.3;skin 1: 11.5" "Cell type enhanced" "Detected in many" "Early spermatids: 50.7;Endometrial ciliated cells: 28.6;Late spermatids: 30.3;Respiratory ciliated cells: 25.9;Syncytiotrophoblasts: 115.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.9" "Lineage enriched" "Detected in many" 5 "T-cells: 8.9" "Group enriched" "Detected in some" 5 "BEWO: 13.0;CAPAN-2: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.59e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (2.79e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-3)" "unprognostic (6.76e-2)" "unprognostic (2.02e-1)" "unprognostic (5.06e-2)" "unprognostic (2.08e-6)" "unprognostic (2.82e-2)" "unprognostic (2.70e-2)" "unprognostic (6.34e-2)" "unprognostic (2.63e-1)" 0.0 0.5 1.1 0.4 1.7 0.2 0.2 0.4 1.0 1.7 0.3 0.0 0.0 0.4 1.1 8.3 1.0 0.2 0.0 0.5 2.1 0.0 0.0 0.2 0.8 2.0 1.7 0.1 0.0 0.0 1.5 4.1 1.1 0.2 0.0 0.8 0.5 0.0 0.2 11.5 0.0 0.0 1.0 0.1 0.1 2.0 2.1 0.3 0.1 0.0 0.8 0.1 1.6 0.4 0.6 0.0 0.7 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.1 4.2 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.6 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.5 0.4 0.6 0.0 1.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 1.1 0.0 1.0 0.9 5.0 1.3 0.0 1.6 8.9 3.4 0.0 0.4 0.1 0.7 5.4 1.4 1.1 1.7 0.4 1.0 0.5 2.1 2.0 1.7 1.1 1.0 2.1 0.4 0.4 0.0 0.0 0.0 2.8 0.0 0.2 1.9 0.6 4.0 0.7 0.9 1.4 1.5 1.6 0.0 0.0 10.2 1.5 0.3 0.0 0.3 50.7 28.6 3.3 1.1 0.0 0.0 2.7 0.2 2.5 0.5 0.0 15.4 14.7 7.8 2.2 0.0 1.9 0.0 7.7 0.0 4.1 0.3 0.4 30.3 0.6 0.8 0.0 0.0 0.3 0.5 1.0 0.5 0.6 3.8 0.0 0.7 0.4 0.3 0.0 0.1 25.9 0.6 0.0 0.0 0.9 19.8 12.7 0.8 0.3 115.5 4.7 0.1 0.2 1.9 ATP1B3 "CD298, FLJ29027" ENSG00000069849 "ATPase Na+/K+ transporting subunit beta 3" P54709 3 141876124-141926549 "CD markers, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 982.6;Late spermatids: 930.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020697, HPA048963" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB020697: , HPA048963: AB_2680574" "unprognostic (2.31e-1)" "unprognostic (1.11e-3)" "unprognostic (2.75e-1)" "prognostic favorable (5.19e-5)" "unprognostic (2.60e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (8.11e-3)" "unprognostic (6.99e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.29e-5)" "unprognostic (5.14e-2)" "unprognostic (2.04e-1)" "unprognostic (7.19e-3)" "unprognostic (6.15e-2)" 229.4 349.6 62.2 81.0 62.8 63.0 87.0 78.5 78.8 98.4 100.5 146.7 112.7 75.7 37.6 182.3 96.2 55.4 102.8 63.6 74.7 128.4 24.5 191.0 41.3 71.1 66.6 180.0 36.7 20.3 168.7 96.7 76.5 102.0 168.0 43.6 85.8 46.2 26.7 259.3 125.0 71.4 68.7 65.7 66.3 75.8 70.6 51.4 75.8 16.0 57.1 101.0 161.2 62.2 280.8 170.1 155.5 145.6 411.7 118.0 354.7 322.2 287.6 224.2 252.1 253.7 136.5 223.3 278.2 243.5 328.4 595.8 157.0 152.2 253.4 120.4 190.0 195.7 161.4 156.8 161.7 164.9 149.1 126.5 355.1 179.1 169.7 162.4 245.7 156.3 135.9 193.7 233.8 114.6 165.6 275.0 213.6 384.5 76.1 225.0 116.4 227.1 191.1 186.7 127.6 86.0 413.2 188.5 455.9 270.7 145.6 197.2 170.7 196.4 76.3 298.8 189.8 138.0 197.6 367.5 259.5 176.5 165.2 69.7 104.1 35.4 70.4 174.3 51.7 39.7 56.3 74.8 103.3 30.4 32.6 59.6 6.7 32.0 260.4 64.8 68.4 103.7 62.2 62.8 78.5 78.8 63.6 74.7 71.1 66.6 76.5 68.7 70.6 62.2 114.7 57.7 41.9 38.2 143.4 492.8 428.3 535.9 326.7 35.9 53.0 46.4 19.7 17.2 177.6 220.7 25.0 281.3 464.5 982.6 41.1 73.9 465.9 86.0 72.2 199.2 56.1 147.1 107.5 60.6 226.8 164.1 24.5 127.2 130.7 94.3 100.6 9.0 305.9 25.2 91.2 65.2 164.8 148.0 678.3 930.5 84.8 455.3 222.3 37.5 364.8 46.3 75.2 46.3 54.7 70.6 321.1 68.4 153.1 396.5 413.3 41.5 33.3 28.4 124.9 99.5 265.2 69.0 200.2 178.4 414.4 391.4 216.1 122.2 134.9 370.2 ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910656-78050395 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 61.1;Microglial cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA012887: AB_1845205, HPA048107: AB_2680266" "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" 3.0 4.3 1.2 3.6 1.7 5.9 6.3 2.3 2.1 3.9 1.6 3.4 3.9 3.6 5.0 4.9 3.5 3.6 2.5 1.3 2.1 4.4 2.3 4.5 4.1 2.1 2.1 3.6 2.4 7.3 2.5 4.0 3.8 5.3 3.4 3.0 5.1 3.4 1.8 11.1 3.4 3.2 1.1 4.7 5.5 1.6 1.6 4.7 4.6 2.9 4.6 3.9 2.8 2.9 3.2 8.3 5.4 5.5 5.0 5.3 0.9 4.8 6.6 2.8 5.7 1.0 3.6 4.7 6.9 4.8 3.3 3.8 7.1 3.9 5.2 7.0 4.8 2.4 7.8 0.8 6.3 4.1 4.1 5.6 1.6 5.9 1.8 6.5 7.3 4.7 19.6 17.4 5.2 2.8 4.6 1.4 1.5 11.2 1.7 3.7 9.0 15.8 4.6 8.8 1.6 20.4 11.9 2.8 6.0 3.3 2.2 1.3 9.4 3.7 3.6 5.2 1.9 5.6 10.7 5.2 6.0 2.5 5.7 7.1 1.5 4.5 1.8 1.5 0.9 1.8 1.2 1.2 1.0 1.4 1.4 2.1 8.1 1.2 1.9 1.0 0.4 1.0 1.2 1.7 2.3 2.1 1.3 2.1 2.1 2.1 3.8 1.1 1.6 2.9 14.3 0.0 8.4 15.7 12.6 7.4 5.1 5.8 13.1 6.4 17.3 10.0 5.1 1.5 8.2 9.2 4.2 2.0 15.0 4.5 1.9 5.6 0.5 5.3 9.2 9.7 4.8 22.5 11.1 13.6 2.2 9.4 20.4 8.8 9.5 6.4 14.6 3.6 14.3 1.7 12.5 4.8 61.1 11.7 6.7 1.1 7.2 12.6 19.6 44.0 5.5 4.4 11.3 37.7 35.0 6.2 4.1 9.8 10.5 4.8 4.1 5.5 10.2 4.1 32.9 10.3 8.7 1.8 5.4 20.5 16.6 2.2 13.8 6.7 5.2 6.6 AVPI1 "PP5395, VIP32, VIT32" ENSG00000119986 "Arginine vasopressin induced 1" Q5T686 10 97677424-97687241 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 100.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 246.7;Granulosa cells: 385.5;Langerhans cells: 326.1;Late spermatids: 278.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 119.7;HHSteC: 119.1;hTCEpi: 230.5;SK-MEL-30: 194.5;U-2197: 134.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037649 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA037649: AB_10671879" "unprognostic (4.57e-2)" "unprognostic (3.28e-2)" "unprognostic (3.04e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-2)" "unprognostic (7.34e-3)" "unprognostic (8.56e-3)" "unprognostic (2.29e-3)" "unprognostic (1.23e-1)" "unprognostic (3.91e-3)" "unprognostic (4.04e-1)" "unprognostic (2.03e-1)" "unprognostic (8.66e-2)" "unprognostic (3.83e-3)" 32.1 41.5 18.5 6.5 25.4 5.0 21.2 21.9 23.2 38.1 16.2 24.6 14.0 11.2 4.7 26.2 18.9 10.4 22.4 18.3 19.8 12.1 46.9 22.5 2.4 23.7 20.2 85.6 9.4 5.6 19.2 16.9 21.9 26.3 18.9 25.5 22.7 16.6 12.5 100.7 15.6 5.3 22.4 20.8 30.5 16.0 20.8 2.0 9.1 3.9 4.4 25.5 46.0 29.5 38.8 99.8 0.5 14.3 20.2 9.1 20.0 18.5 100.7 25.0 37.5 18.8 47.2 0.8 13.0 10.5 18.0 40.0 7.6 32.3 9.4 1.0 8.9 2.6 119.7 52.6 119.1 2.6 3.0 14.6 230.5 18.7 49.1 22.8 3.4 3.6 5.7 2.0 14.0 33.4 1.7 3.1 3.5 10.6 9.3 1.3 11.3 1.5 24.9 20.9 1.7 4.0 63.9 22.7 194.5 3.2 17.2 3.1 5.5 5.9 11.7 134.4 4.6 4.4 3.3 0.8 22.2 8.1 3.8 0.0 6.2 2.3 4.2 5.7 2.0 2.8 2.8 3.1 11.1 2.0 3.0 3.7 0.5 2.0 0.5 2.3 2.6 2.9 18.5 25.4 21.9 23.2 18.3 19.8 23.7 20.2 21.9 22.4 20.8 29.5 6.3 19.2 19.0 0.7 8.0 96.0 87.6 246.7 145.1 9.6 13.6 16.8 9.7 52.9 63.4 38.6 6.2 149.6 15.4 137.5 43.0 18.8 60.9 33.2 17.1 11.4 31.8 2.1 3.6 24.1 64.8 23.4 58.1 57.9 6.3 385.5 34.2 42.4 41.8 13.5 4.3 70.4 48.8 21.7 326.1 278.5 10.2 49.6 83.6 0.0 6.4 128.2 2.1 0.5 4.4 43.3 100.6 14.7 5.9 55.2 109.0 11.2 16.7 14.6 6.6 10.2 19.3 3.5 4.9 68.0 108.4 194.7 19.0 10.9 100.6 106.3 BICD2 KIAA0699 ENSG00000185963 "BICD cargo adaptor 2" Q8TD16 9 92711363-92764833 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Squamous epithelial cells: 103.2;Suprabasal keratinocytes: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023013, HPA024452" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane, Cytosol" "HPA023013: AB_1845352, HPA024452: AB_1845353" "unprognostic (9.99e-3)" "unprognostic (1.98e-1)" "unprognostic (7.84e-3)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "unprognostic (2.86e-1)" "unprognostic (2.37e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (6.54e-3)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" 15.4 10.6 11.4 13.5 10.0 12.0 10.9 10.9 10.5 20.8 7.8 18.5 4.6 15.5 6.0 47.0 12.8 9.4 19.8 11.1 8.6 9.1 8.5 16.0 14.7 11.0 9.8 12.5 8.9 17.7 6.0 10.4 10.3 11.3 5.0 6.5 14.6 13.1 22.3 63.4 10.4 13.7 10.5 17.3 9.5 9.4 10.0 13.8 10.0 15.3 16.8 15.2 30.9 12.3 32.6 26.5 19.2 19.8 36.6 25.1 27.1 30.8 22.2 17.2 13.6 15.6 14.4 36.3 19.5 34.4 22.0 99.4 21.8 49.1 19.4 17.4 23.5 19.2 25.6 21.7 21.8 26.9 30.0 25.8 67.1 28.8 22.0 20.4 26.0 15.4 19.3 27.5 38.1 21.4 25.6 16.7 13.3 23.8 32.0 27.8 41.8 19.3 27.8 27.0 13.4 20.7 21.7 19.9 14.3 19.2 8.2 12.3 34.9 31.8 21.1 53.9 33.9 22.5 17.5 31.9 26.9 16.3 28.4 1.6 3.4 4.4 1.2 3.6 1.2 1.8 1.4 1.6 3.8 2.0 1.3 1.2 7.5 1.1 5.9 3.2 0.9 1.7 11.4 10.0 10.9 10.5 11.1 8.6 11.0 9.8 10.3 10.5 10.0 12.3 21.7 28.9 12.7 14.7 27.6 73.7 17.1 19.2 83.6 12.8 11.4 10.2 54.5 8.6 16.2 7.3 6.2 8.5 26.1 3.4 3.9 10.1 6.5 21.3 26.7 26.4 10.8 16.0 16.2 5.1 6.5 26.0 5.6 21.1 24.1 13.0 19.2 7.5 14.2 15.2 14.0 1.9 12.2 32.4 30.2 7.6 21.1 40.7 16.0 19.7 38.9 22.0 7.2 9.5 18.5 8.5 3.6 33.4 22.1 18.7 0.8 6.7 14.0 6.4 19.7 23.0 33.1 9.7 8.4 103.2 130.8 7.3 17.2 13.8 3.6 20.3 BLMH BH ENSG00000108578 "Bleomycin hydrolase" Q13867 17 30248203-30292056 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 130.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039548, HPA064307" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 42000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA039548: AB_10805479, HPA064307: AB_2685241" "unprognostic (6.85e-2)" "unprognostic (2.79e-1)" "unprognostic (1.48e-1)" "unprognostic (2.46e-1)" "unprognostic (1.76e-1)" "unprognostic (2.54e-2)" "unprognostic (3.91e-3)" "unprognostic (2.07e-1)" "unprognostic (2.05e-3)" "unprognostic (6.69e-3)" "unprognostic (1.95e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.22e-3)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" 20.6 13.5 13.4 18.2 15.0 18.1 20.4 15.9 17.6 19.1 14.5 18.8 12.4 21.2 21.1 28.3 14.7 18.4 15.6 13.5 15.2 22.0 14.0 16.0 26.0 15.6 14.1 13.9 26.8 21.7 9.7 27.4 15.4 14.4 15.4 14.7 15.6 14.4 28.8 130.3 18.3 22.4 14.7 20.6 16.2 15.9 14.2 36.3 16.5 19.0 26.9 17.9 21.5 16.2 40.3 62.9 61.5 41.6 40.6 43.8 27.8 36.5 24.0 59.1 50.8 93.2 11.9 119.5 63.3 31.1 26.1 27.1 135.5 52.8 50.1 31.5 101.4 73.5 54.6 80.0 58.3 136.1 43.2 50.5 3.5 46.5 26.5 47.1 87.2 98.2 157.9 47.6 24.6 31.0 168.1 98.6 57.2 0.0 29.2 143.0 154.5 78.9 46.8 35.6 135.1 48.4 32.6 63.2 42.2 106.6 42.9 68.5 54.5 35.0 69.2 16.0 66.0 55.8 124.1 159.3 26.7 0.2 47.6 0.0 8.8 1.5 15.3 6.2 25.3 6.5 18.2 20.2 10.1 7.3 16.4 17.8 1.2 16.3 3.3 10.1 20.0 9.9 13.4 15.0 15.9 17.6 13.5 15.2 15.6 14.1 15.4 14.7 14.2 16.2 21.0 3.2 12.6 13.4 8.8 15.9 16.7 10.6 19.4 20.2 10.3 6.6 17.8 12.8 4.0 11.0 12.5 49.6 15.6 7.6 7.9 17.4 8.4 7.4 28.2 24.0 18.0 22.5 19.0 14.2 38.0 18.3 11.2 7.0 43.8 30.5 25.7 6.9 25.0 13.5 20.9 8.4 6.1 18.9 7.1 6.6 16.1 13.0 10.6 18.7 12.2 9.9 22.6 29.1 22.6 7.2 9.6 24.8 20.0 13.0 11.5 20.0 5.5 15.7 6.6 12.9 19.7 14.9 29.1 24.0 12.6 27.5 20.9 34.8 11.5 7.6 BTG1 APRO2 ENSG00000133639 "BTG anti-proliferation factor 1" P62324 12 92140278-92145846 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2751.6;Langerhans cells: 2893.3;Suprabasal keratinocytes: 3004.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 33.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005972 Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA005972: AB_1078303" "prognostic favorable (4.36e-5)" "unprognostic (1.43e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.50e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (5.79e-2)" "unprognostic (9.81e-2)" 91.5 36.9 1.9 19.8 2.0 93.9 80.1 33.5 4.1 62.3 1.4 38.9 8.5 45.6 1.5 29.5 55.9 7.1 45.2 2.5 4.6 52.4 69.7 55.5 23.8 3.6 2.6 45.6 63.7 8.3 26.2 6.2 3.7 40.5 4.8 5.2 30.5 4.5 20.5 120.6 58.4 8.2 3.5 92.2 39.3 12.4 3.1 20.1 21.9 3.7 18.2 38.5 60.1 3.0 5.7 5.4 3.5 0.9 13.4 16.9 3.2 8.0 6.3 2.3 2.3 2.4 1.6 5.7 1.5 3.3 3.5 3.9 1.6 3.0 2.2 9.8 8.8 0.8 2.9 1.3 15.0 3.7 1.9 14.1 11.9 4.5 11.7 8.5 5.0 2.4 4.6 7.1 3.4 3.7 5.5 9.4 2.2 3.0 11.0 15.2 2.4 1.5 5.5 6.5 3.4 7.8 6.1 4.4 17.3 2.1 21.5 7.7 2.6 3.9 1.3 3.6 3.7 14.0 6.3 8.9 3.1 2.4 4.6 36.2 21.8 151.8 22.8 16.2 27.8 92.4 47.3 40.7 9.2 105.5 133.1 53.6 75.9 68.8 22.8 8.0 66.8 51.3 1.9 2.0 33.5 4.1 2.5 4.6 3.6 2.6 3.7 3.5 3.1 3.0 1186.6 96.1 185.4 12.1 2512.8 2751.6 1030.9 206.6 912.9 592.7 607.5 573.8 119.5 1009.4 140.4 174.7 196.0 412.8 1907.2 672.9 320.8 388.1 411.8 216.7 258.8 709.0 452.4 230.7 7.9 255.8 416.3 529.1 406.7 264.7 286.6 197.4 339.1 274.9 361.4 424.0 20.6 373.8 193.3 564.3 2893.3 213.7 287.1 1251.4 983.6 31.9 1241.2 877.6 1354.3 22.1 8.4 364.4 668.7 241.9 758.5 791.3 667.9 162.6 53.0 377.2 539.0 870.7 723.5 130.1 101.5 508.7 3004.2 1342.7 2354.0 786.4 410.9 1513.3 C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA002569: AB_1078334" "prognostic favorable (5.05e-4)" "unprognostic (1.31e-2)" "unprognostic (2.97e-2)" "unprognostic (2.23e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (4.86e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (7.11e-2)" 8.3 4.8 6.5 5.7 7.7 12.6 8.2 6.7 7.0 11.2 8.5 8.8 7.4 8.7 11.4 7.4 9.5 9.2 5.6 6.2 7.3 11.1 8.9 6.7 10.1 7.7 7.2 10.3 9.6 8.3 6.5 5.0 7.5 9.6 9.6 4.4 8.0 5.7 6.7 18.3 8.1 6.8 6.7 10.6 8.3 4.0 7.2 15.7 11.5 7.9 10.5 8.6 8.3 9.5 5.7 10.5 8.8 12.3 13.9 30.8 12.2 6.6 10.2 5.1 6.7 6.6 16.5 16.0 6.1 6.0 7.2 11.8 5.4 16.6 4.7 6.3 3.8 10.1 14.0 15.3 12.1 7.4 8.3 22.4 12.8 7.6 9.6 18.5 9.6 10.1 11.1 3.4 5.3 16.3 9.5 13.6 3.0 12.3 7.3 15.1 8.4 9.8 6.7 8.6 31.8 13.8 8.8 8.4 9.0 9.4 13.0 12.8 5.5 9.6 12.7 4.3 6.7 11.9 3.6 11.0 6.6 9.1 10.0 12.2 7.7 22.9 8.1 7.4 7.2 10.4 6.5 8.5 9.1 10.0 9.8 9.4 11.2 10.4 13.0 6.3 13.4 7.1 6.5 7.7 6.7 7.0 6.2 7.3 7.7 7.2 7.5 6.7 7.2 9.5 3.1 9.6 1.1 14.7 8.7 3.1 4.1 4.6 10.2 1.4 4.0 4.1 3.3 1.5 2.6 0.0 4.2 4.3 7.8 3.7 7.9 3.9 0.8 3.3 2.6 3.3 15.7 6.5 3.4 3.0 5.7 3.9 7.7 3.0 7.0 4.7 1.4 1.5 3.8 0.0 3.4 6.3 4.1 5.5 2.5 1.5 4.4 3.4 5.4 9.4 1.9 4.1 7.2 7.1 9.9 3.1 7.3 4.1 5.2 1.9 4.6 3.6 4.6 2.0 6.6 3.8 3.7 2.9 8.2 5.3 1.6 3.0 5.2 4.1 5.1 2.5 C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 14.9;Glandular and luminal cells: 28.4;Squamous epithelial cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA028496: AB_10602698" "unprognostic (3.25e-1)" "prognostic unfavorable (8.52e-6)" "unprognostic (8.41e-3)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-2)" "unprognostic (9.98e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.95e-1)" "unprognostic (2.81e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.40e-2)" 0.6 0.9 0.7 2.4 0.7 1.1 2.2 1.8 0.7 0.9 0.2 1.6 1.3 0.8 2.0 4.0 1.1 0.9 1.5 0.7 0.9 1.9 1.7 0.9 4.3 0.8 0.8 0.9 0.8 1.2 0.8 1.1 0.8 1.6 2.0 0.9 1.9 0.9 1.0 6.7 2.8 0.6 0.7 4.2 1.7 1.3 1.1 2.1 1.2 0.9 2.4 1.9 1.7 0.8 4.7 2.4 1.5 0.8 2.0 2.3 3.5 2.6 3.4 3.1 3.2 4.9 3.5 4.9 1.5 1.7 1.9 9.3 0.9 7.6 3.6 4.9 3.1 3.2 1.7 0.4 2.8 4.6 1.4 1.4 6.6 3.9 6.3 2.6 1.8 6.6 6.5 3.5 2.7 2.4 3.9 4.7 6.4 3.2 4.1 4.0 7.2 6.9 2.7 4.0 6.0 6.5 3.5 2.7 4.0 3.4 4.2 2.4 1.7 2.6 3.1 2.7 4.2 3.2 3.4 5.4 2.3 3.7 3.8 4.7 0.8 0.7 1.3 0.9 0.9 1.8 0.6 1.0 1.6 3.7 1.1 1.2 0.5 1.5 0.5 2.7 0.6 0.9 0.7 0.7 1.8 0.7 0.7 0.9 0.8 0.8 0.8 0.7 1.1 0.8 0.6 3.2 2.2 0.0 1.1 2.2 6.1 4.6 6.8 1.6 3.7 2.8 2.0 0.0 1.8 0.0 0.0 3.9 1.5 3.5 7.9 1.9 0.1 14.9 1.8 0.8 3.6 2.1 0.5 2.0 5.0 0.9 2.6 28.4 1.3 2.2 1.4 2.3 2.8 1.7 0.6 5.9 0.0 1.3 0.3 0.6 2.5 1.6 0.0 1.0 1.3 2.2 0.0 0.0 0.3 4.1 3.5 0.0 0.6 5.1 2.4 7.4 1.8 1.3 0.0 0.4 1.0 3.6 4.7 25.0 4.8 4.0 1.1 2.8 3.4 12.1 C3orf52 "FLJ23186, TTMP" ENSG00000114529 "Chromosome 3 open reading frame 52" Q5BVD1 3 112086335-112131004 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 17.4;skin 1: 26.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 129.6;Pancreatic endocrine cells: 82.8;Prostatic glandular cells: 75.6;Syncytiotrophoblasts: 75.0;Urothelial cells: 132.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 26.4;U-698: 30.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007678, HPA008119, HPA011968" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA007678: , HPA008119: AB_1848824, HPA011968: AB_1848826" "unprognostic (8.86e-2)" "unprognostic (1.71e-1)" "unprognostic (3.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-3)" "unprognostic (3.49e-4)" "unprognostic (2.54e-1)" "unprognostic (1.39e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.71e-2)" "unprognostic (3.76e-6)" "unprognostic (3.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-2)" "unprognostic (9.59e-2)" 1.2 1.0 0.1 1.2 0.2 0.6 2.7 0.2 0.3 0.7 0.2 7.5 3.3 0.9 0.0 2.6 0.7 5.0 4.0 0.2 0.1 4.8 0.3 3.8 1.2 0.0 0.1 0.2 17.4 0.0 2.0 3.3 0.1 1.7 13.7 0.1 3.8 3.4 0.5 26.3 5.2 0.9 0.1 0.7 13.7 0.9 0.3 6.6 7.6 0.1 2.0 5.8 1.6 0.1 11.0 2.0 4.2 0.0 0.6 0.0 1.8 15.5 6.7 10.1 11.3 26.4 10.1 0.4 1.9 3.1 4.4 8.7 6.1 0.3 19.4 0.0 2.8 7.9 1.8 1.9 4.6 0.0 0.1 0.6 8.7 5.2 15.0 5.4 2.2 0.0 2.8 2.8 7.5 1.7 0.3 0.0 12.3 7.9 0.6 0.3 13.2 0.0 18.1 16.5 0.5 0.9 2.4 5.2 6.3 6.8 9.5 0.0 5.8 3.6 5.5 0.0 0.0 3.9 0.0 30.1 2.7 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.8 16.0 10.0 0.3 1.6 32.5 129.6 10.0 45.5 0.0 14.8 3.3 2.1 4.3 19.3 18.4 0.0 18.1 0.7 30.4 0.0 26.3 24.2 24.8 3.1 3.5 11.9 0.0 3.2 35.9 25.6 4.7 64.2 44.1 0.0 0.4 0.4 0.0 1.9 0.0 0.6 56.6 8.2 0.3 2.7 23.3 0.3 1.0 1.8 1.0 2.6 0.0 0.0 0.5 0.3 82.8 30.7 0.4 4.6 75.6 7.8 2.1 14.8 0.0 0.0 4.6 4.7 3.2 5.3 44.0 33.5 75.0 2.0 3.0 8.9 132.5 C5orf46 "MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 181.8;skin 1: 113.1" "Group enriched" "Detected in some" 12 "Early spermatids: 320.9;Late spermatids: 189.9" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Region enriched" "Detected in single" 10 "cerebellum: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 54.2;PC-3: 90.8;SiHa: 20.2;U-2 OS: 58.2;U-251 MG: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" NA NA 54000 "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 13.5 2.3 0.1 1.6 0.7 0.4 0.0 0.1 0.4 0.4 0.0 0.2 9.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.2 0.9 0.0 0.6 181.8 0.1 0.8 113.1 0.0 3.2 0.0 0.0 0.0 19.2 0.0 0.3 0.2 0.1 0.3 0.0 3.6 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 2.4 1.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.6 0.0 0.2 0.2 0.0 4.6 0.2 0.0 0.0 0.0 0.0 1.1 0.0 8.9 54.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 20.2 0.3 0.3 11.1 0.0 0.0 0.0 10.0 58.2 0.8 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 9.2 3.7 11.0 15.7 0.2 1.8 0.0 0.5 0.2 0.0 0.0 15.9 320.9 0.7 0.4 0.3 0.0 0.0 0.0 3.3 0.6 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 189.9 1.8 0.2 3.6 0.0 0.6 7.7 0.0 0.0 0.0 4.2 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 1.1 0.8 0.0 20.6 1.4 0.1 0.0 0.0 0.2 C6orf15 STG ENSG00000204542 "Chromosome 6 open reading frame 15" Q6UXA7 6 31111223-31112575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 5.5;lymphoid tissue: 3.5;skin 1: 6.7" "Cell type enriched" "Detected in some" 14 "Breast glandular cells: 73.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "RH-30: 13.4;U-2 OS: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA001436 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 30: Mammary glandular cells - Lactation" "HPA001436: AB_2243752" "unprognostic (2.73e-2)" "unprognostic (5.39e-2)" "unprognostic (1.46e-2)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.35e-1)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 3.5 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.0 1.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CAMSAP3 "KIAA1543, Nezha, PPP1R80" ENSG00000076826 "Calmodulin regulated spectrin associated protein family member 3" Q9P1Y5 19 7595863-7618304 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 40.0;Gastric mucus-secreting cells: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 26.7;Hep G2: 15.6;MCF7: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043830, HPA062149" Enhanced Approved Nucleoplasm,Centrosome NA NA "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Centrosome" "HPA043830: AB_10795879, HPA062149: AB_2684698" "unprognostic (3.83e-2)" "unprognostic (1.18e-1)" "unprognostic (8.67e-2)" "unprognostic (7.90e-3)" "unprognostic (3.66e-1)" "unprognostic (3.87e-3)" "unprognostic (7.00e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (1.41e-1)" "prognostic favorable (7.55e-7)" "unprognostic (2.16e-2)" "unprognostic (3.88e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-3)" 0.4 3.3 3.2 0.8 4.4 0.0 5.3 2.5 9.0 7.7 0.1 10.3 14.9 0.5 2.3 24.8 3.1 1.6 0.4 4.2 0.7 12.0 24.3 4.6 0.2 2.5 0.0 0.5 20.6 2.7 8.2 0.4 0.4 10.2 2.4 3.2 18.1 4.5 0.2 62.7 11.5 0.1 0.0 0.6 15.5 13.0 0.2 0.5 11.1 0.0 1.1 3.6 13.4 2.4 11.2 1.8 0.3 0.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 26.7 5.8 3.1 4.5 0.0 1.2 9.7 4.3 2.8 0.0 2.0 10.1 0.0 0.5 15.6 0.0 0.0 4.4 0.0 5.5 0.0 0.4 0.4 0.0 4.5 0.9 0.0 0.0 13.0 0.2 0.2 6.6 8.4 4.7 0.7 0.0 3.7 1.9 6.0 8.2 8.7 1.3 12.5 0.0 1.6 10.4 1.7 0.0 0.0 2.0 0.0 0.4 5.0 1.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 2.5 9.0 4.2 0.7 2.5 0.0 0.4 0.0 0.2 2.4 0.2 9.6 19.2 3.3 1.1 9.8 2.7 2.4 3.4 22.7 19.3 12.1 1.5 20.0 5.3 9.2 0.0 0.5 0.2 40.0 3.9 5.7 4.4 9.6 1.4 1.5 13.1 0.0 9.1 11.8 0.7 0.2 38.7 13.5 5.7 8.6 0.4 24.8 0.2 10.1 10.1 22.4 0.0 1.9 1.2 2.9 1.5 1.0 0.0 1.9 0.0 1.5 0.0 4.5 0.6 13.1 28.4 0.0 0.6 6.2 29.2 15.6 2.9 13.4 0.0 0.0 1.1 0.4 2.8 9.8 18.9 0.5 0.9 1.5 18.4 8.0 CCDC3 DKFZp761F241 ENSG00000151468 "Coiled-coil domain containing 3" Q9BQI4 10 12896625-13099652 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 132.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 50.1;Excitatory neurons: 100.2;Inhibitory neurons: 41.3;Peritubular cells: 60.5;Smooth muscle cells: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 10.4;HAP1: 19.1;HDLM-2: 32.4;hTERT-RPE1: 14.8;U-2 OS: 20.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 20.8" HPA062425 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA062425: AB_2684759" "unprognostic (2.26e-1)" "unprognostic (6.65e-3)" "unprognostic (1.70e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (5.08e-2)" "unprognostic (3.11e-2)" "unprognostic (2.99e-2)" "unprognostic (5.56e-3)" "unprognostic (5.41e-2)" "unprognostic (4.25e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.54e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (3.88e-2)" 91.8 11.0 32.9 5.9 35.2 0.1 37.2 17.9 40.2 48.1 17.8 10.1 6.6 25.0 41.3 60.4 56.7 70.7 21.9 37.1 20.1 19.0 20.6 21.0 12.4 18.6 19.1 86.2 6.5 4.9 10.2 22.2 19.6 35.2 7.4 1.6 7.1 22.0 30.7 132.2 14.3 24.2 19.8 24.7 13.1 11.6 21.7 42.0 20.0 13.3 4.2 23.2 27.4 30.5 0.0 0.2 1.7 9.4 0.0 0.0 0.1 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.7 0.0 10.4 1.9 19.1 3.6 0.6 32.4 8.1 0.0 0.2 0.0 0.7 0.0 0.0 2.3 2.3 0.4 0.0 14.8 0.9 0.8 0.0 0.2 1.0 0.2 0.0 5.4 1.5 0.0 0.1 0.0 4.1 0.3 0.0 0.0 3.6 1.6 7.0 1.0 0.0 4.4 0.0 0.0 0.0 0.0 20.0 1.2 0.3 0.0 0.0 0.0 0.1 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.9 35.2 17.9 40.2 37.1 20.1 18.6 19.1 19.6 19.8 21.7 30.5 12.4 0.0 0.0 10.1 0.1 50.1 6.4 26.3 13.6 1.2 0.9 4.7 7.9 1.5 2.1 0.0 0.0 0.3 1.3 0.1 1.9 0.0 0.2 0.1 0.7 27.2 0.0 0.0 100.2 0.0 0.2 16.0 0.5 0.4 0.0 16.4 8.2 0.2 0.3 0.0 41.3 0.1 0.0 0.0 6.4 1.5 22.4 0.6 14.2 3.7 0.0 0.3 0.0 22.6 23.2 0.1 2.5 60.5 0.0 3.0 0.3 0.4 1.1 2.1 32.9 7.9 119.4 0.0 5.7 2.1 37.2 0.3 1.0 6.0 0.3 1.3 CD207 "CLEC4K, Langerin" ENSG00000116031 "CD207 molecule" Q9UJ71 2 70830211-70835816 "CD markers, Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 87.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.0;Langerhans cells: 9.7;Macrophages: 7.6;Melanocytes: 5.4;Suprabasal keratinocytes: 5.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.1" "Cell line enriched" "Detected in some" 4 "AN3-CA: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002222, HPA011216" Enhanced Uncertain Cytosol No NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB002222: AB_563850, HPA011216: AB_1078453" "unprognostic (1.45e-2)" "unprognostic (8.28e-3)" "unprognostic (9.34e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-3)" "unprognostic (1.05e-1)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.63e-1)" "unprognostic (7.92e-4)" "unprognostic (2.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (2.46e-2)" 0.4 0.1 0.0 0.3 0.0 0.0 3.2 0.0 0.0 1.6 0.1 1.2 3.7 0.8 0.4 17.8 0.9 2.0 0.2 0.0 0.0 0.1 0.7 1.6 0.9 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 2.4 2.7 5.5 1.1 0.8 0.8 87.7 4.9 0.7 0.0 3.7 1.4 0.5 0.0 3.4 0.1 0.3 4.8 1.4 1.7 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 1.6 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.6 4.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.2 0.0 7.6 5.4 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.0 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823052-64844653 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 14.8;Gastric mucus-secreting cells: 23.0;Paneth cells: 18.3;Squamous epithelial cells: 19.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.3;HaCaT: 22.5;MCF7: 30.7;RT4: 18.4;SK-BR-3: 18.4;T-47d: 18.1" "Region enriched" "Detected in all" 4 "cerebellum: 10.5" "Low region specificity" "Detected in some" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 4.9 0.2 1.4 0.3 2.1 4.8 9.7 1.2 5.4 5.5 8.8 10.6 0.4 2.0 26.5 3.8 2.8 0.4 0.4 0.3 7.7 0.9 7.8 1.3 0.4 0.7 2.2 14.1 6.4 11.0 4.2 1.0 8.5 4.5 0.3 17.7 3.7 0.2 33.7 9.3 0.2 0.3 1.8 12.2 3.3 0.3 2.4 6.0 0.0 2.0 5.8 13.0 0.3 8.9 1.2 0.8 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 11.7 7.5 0.1 4.3 0.0 0.4 22.5 1.3 8.8 0.0 0.4 3.6 0.7 5.3 3.8 0.0 0.3 2.2 0.0 10.9 0.1 0.1 0.1 0.1 3.5 6.1 0.1 0.0 30.7 0.2 1.7 2.7 8.3 1.3 1.3 0.5 4.3 5.5 18.4 15.6 0.7 2.8 18.4 0.5 4.3 18.1 0.4 0.1 0.0 3.1 0.1 0.1 2.1 2.2 2.2 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 9.7 1.2 0.4 0.3 0.4 0.7 1.0 0.3 0.3 0.3 1.0 9.6 7.9 0.0 1.2 6.5 2.3 3.6 9.6 0.0 5.1 5.8 1.8 2.8 9.6 1.8 0.0 6.4 1.7 14.8 0.0 2.4 0.6 13.2 0.7 0.4 3.6 0.8 0.1 6.2 4.9 0.7 23.0 7.9 1.3 0.4 0.0 0.0 1.0 0.0 0.1 4.8 2.0 0.0 0.4 0.8 0.0 1.3 0.0 0.0 1.2 0.8 1.0 0.0 0.1 2.9 18.3 0.0 0.1 1.6 12.4 0.5 9.5 0.0 0.0 2.2 0.8 1.7 1.3 19.3 8.1 6.7 1.4 0.6 5.7 3.4 CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 31.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Basal respiratory cells: 28.1;Club cells: 31.1;Endometrial ciliated cells: 31.8;Glandular and luminal cells: 42.6;Respiratory ciliated cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cell line enhanced" "Detected in many" "A549: 68.4;RPTEC TERT1: 48.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 280000 "Cluster 43: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" 0.7 0.8 0.4 3.1 0.9 0.8 7.8 1.5 0.5 9.9 1.2 1.6 0.9 3.7 10.2 11.5 15.4 1.4 3.4 1.0 0.4 17.1 5.2 12.5 5.9 2.4 3.9 0.2 2.6 6.3 2.4 1.0 1.4 5.0 1.8 0.5 12.0 3.9 0.2 31.5 1.6 1.1 1.6 3.3 5.4 1.3 2.2 2.4 3.7 0.1 7.9 3.9 3.7 1.0 22.3 68.4 11.3 10.6 0.0 0.0 6.5 2.3 3.4 2.3 1.3 21.7 21.9 0.2 32.1 1.3 22.0 35.0 7.5 28.7 2.0 0.0 10.2 0.0 25.6 2.0 1.0 3.2 1.8 0.0 43.5 0.0 26.2 31.6 0.4 1.7 0.3 0.4 0.0 38.4 0.1 11.9 4.5 12.1 8.1 0.1 0.1 8.1 48.7 13.5 0.7 0.9 16.1 17.3 3.7 7.9 39.7 16.7 0.9 0.1 0.3 0.0 0.4 10.6 1.1 10.5 15.2 0.1 12.9 0.0 0.0 0.0 0.2 0.1 0.2 2.2 0.1 0.1 0.0 1.9 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.4 0.9 1.5 0.5 1.0 0.4 2.4 3.9 1.4 1.6 2.2 1.0 0.5 41.7 23.5 0.0 5.8 17.1 4.1 28.1 8.0 0.2 14.2 5.2 12.7 2.8 31.1 5.5 0.0 1.9 2.3 0.8 0.0 1.8 2.3 31.8 5.0 5.6 1.2 0.0 1.2 0.7 1.9 1.0 2.6 42.6 0.0 0.6 1.8 1.5 2.4 0.0 1.2 2.8 6.1 0.0 4.1 10.3 0.0 1.1 5.4 1.0 1.1 1.1 0.0 0.5 0.7 4.0 0.3 0.0 1.1 4.3 0.0 8.2 60.3 0.3 0.0 0.1 2.8 0.4 0.6 12.6 15.6 0.8 1.1 0.0 1.7 5.1 CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67009758 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.9;skin 1: 13.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 44.4;Excitatory neurons: 53.6;Oligodendrocytes: 37.6;Respiratory ciliated cells: 47.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.3" "Region enhanced" "Detected in many" "white matter: 10.2" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 19.1;HMC-1: 5.2;PC-3: 4.5;SiHa: 7.8;SK-BR-3: 5.7;U-266/70: 5.9" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "HPA035701: AB_10696357" "unprognostic (6.34e-2)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (3.26e-2)" "unprognostic (1.99e-1)" "unprognostic (6.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.93e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-3)" 3.6 1.5 1.2 0.8 2.6 1.2 2.5 0.1 2.5 1.0 0.0 0.6 0.8 0.5 3.9 1.0 16.9 0.8 2.4 2.3 1.0 2.6 8.4 1.5 0.7 1.7 0.2 1.0 1.1 3.1 3.6 1.0 1.2 0.9 0.7 0.8 4.3 2.1 4.9 13.6 0.8 0.3 0.0 0.5 1.4 0.8 0.8 0.7 2.7 0.2 0.9 1.2 0.7 10.2 0.2 1.5 0.1 0.0 0.9 0.8 0.0 0.4 0.7 0.1 0.0 0.0 2.3 0.0 0.0 1.5 0.0 0.7 0.0 0.2 0.0 19.1 0.0 0.0 1.2 0.0 0.1 0.0 5.2 1.8 3.5 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 4.5 0.2 0.0 1.1 0.0 0.3 1.4 0.9 7.8 5.7 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 5.9 2.2 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.5 2.5 0.5 0.6 1.0 0.5 0.8 0.0 0.9 0.2 0.0 0.0 3.5 1.2 0.3 0.7 1.2 2.6 0.1 2.5 2.3 1.0 1.7 0.2 1.2 0.0 0.8 10.2 0.4 0.0 11.4 2.0 3.5 5.4 5.7 5.0 3.4 23.1 44.4 7.7 2.8 4.3 7.3 5.5 14.6 4.7 3.9 4.1 1.9 0.9 1.7 9.9 1.4 1.0 9.0 0.0 53.6 1.6 0.9 3.9 3.1 11.1 9.5 4.9 1.1 22.1 5.6 0.0 29.7 1.8 4.1 4.1 2.1 1.2 13.7 3.2 0.0 4.7 5.7 8.3 4.1 6.6 37.6 0.9 9.7 12.8 1.3 3.5 5.8 1.5 47.1 15.3 0.0 1.5 1.8 32.1 11.8 4.1 5.3 4.5 3.3 13.5 3.5 7.5 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL6A5 "COL29A1, FLJ35880, VWA4" ENSG00000172752 "Collagen type VI alpha 5 chain" 3 130345516-130484844 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lung: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 3.4;Early spermatids: 5.6;Erythroid cells: 3.8;Fibroblasts: 5.5;Langerhans cells: 5.2;Late spermatids: 3.0;Suprabasal keratinocytes: 3.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 64 "HDLM-2: 15.8" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043138 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA043138: AB_10796687" "unprognostic (3.45e-2)" "unprognostic (4.08e-2)" "unprognostic (6.01e-3)" "unprognostic (2.32e-1)" "unprognostic (3.42e-2)" "unprognostic (1.46e-6)" "unprognostic (8.44e-2)" "unprognostic (2.07e-3)" "unprognostic (2.47e-1)" "unprognostic (1.71e-1)" "unprognostic (7.58e-8)" "unprognostic (3.85e-2)" "unprognostic (4.51e-1)" "unprognostic (1.54e-1)" "unprognostic (2.79e-2)" 0.0 0.0 0.0 0.1 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.7 0.0 0.0 0.0 1.0 0.8 0.1 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.3 0.0 3.8 0.2 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.2 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 3.4 0.0 0.2 0.0 0.0 0.0 COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 72.5;Basal respiratory cells: 59.3;Basal squamous epithelial cells: 67.2;Endometrial stromal cells: 45.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 65.7;HaCaT: 63.5;HBEC3-KT: 100.6;HDLM-2: 97.8;HeLa: 146.2;SiHa: 82.8" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" 0.8 1.1 1.4 3.8 1.0 0.1 4.9 2.8 2.1 24.3 0.4 2.9 1.7 12.1 6.7 21.8 6.4 4.0 3.2 0.3 6.5 7.4 1.3 1.7 1.2 7.0 3.2 3.4 0.4 0.0 2.5 1.6 3.0 34.2 0.9 1.4 11.5 12.2 3.5 98.2 4.1 2.5 2.6 6.5 2.1 3.6 6.5 1.2 0.5 0.6 1.3 6.6 29.2 0.6 0.2 25.4 1.2 0.5 9.2 12.3 31.0 65.7 40.8 16.9 10.0 0.4 0.5 0.1 2.0 15.0 15.4 63.5 0.0 100.6 3.1 97.8 0.5 0.2 146.2 4.3 25.6 0.0 0.4 19.9 58.8 34.4 26.8 23.1 0.0 0.7 0.5 0.7 2.0 0.3 0.0 0.9 3.1 1.3 1.3 0.5 2.2 0.2 9.2 0.2 0.2 0.2 82.8 0.1 0.8 3.7 1.3 0.3 0.0 5.6 3.2 3.2 50.1 1.8 1.8 0.1 49.0 0.4 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 2.8 2.1 0.3 6.5 7.0 3.2 3.0 2.6 6.5 0.6 0.4 0.0 0.0 10.7 0.2 72.5 24.1 59.3 67.2 17.7 1.0 10.2 6.6 0.0 10.6 11.0 10.4 1.4 0.1 0.6 0.0 0.9 11.8 3.1 45.3 1.4 1.8 0.0 6.8 0.7 1.0 8.3 1.1 4.0 0.0 0.8 0.4 0.7 1.6 8.4 11.6 0.7 0.0 0.3 4.2 6.3 5.0 0.8 8.8 8.4 0.1 2.6 0.0 4.0 4.4 15.6 0.1 5.7 0.0 5.7 0.2 0.3 2.5 12.9 0.0 2.0 13.4 2.6 1.5 11.3 24.2 1.2 0.8 5.0 0.2 5.8 COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 77.6;heart muscle: 65.3;skin 1: 80.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 19.3;Early spermatids: 37.0;Fibroblasts: 32.0;Glandular and luminal cells: 32.0;Late spermatids: 75.3;Spermatocytes: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 859.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA077555: " "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (9.08e-5)" "prognostic unfavorable (2.04e-4)" "unprognostic (8.05e-2)" "unprognostic (8.45e-2)" "unprognostic (3.62e-2)" "unprognostic (5.12e-2)" "unprognostic (1.65e-1)" "unprognostic (1.55e-2)" "unprognostic (2.18e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (1.52e-6)" "unprognostic (5.96e-3)" "unprognostic (1.44e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (6.95e-4)" 77.6 0.2 0.0 1.1 0.2 0.0 11.0 1.3 0.2 7.5 0.0 2.3 0.0 4.6 7.6 9.5 1.2 16.1 65.3 0.0 0.0 5.2 0.3 8.0 3.6 0.3 0.1 0.4 2.8 2.2 0.4 8.2 0.1 10.2 0.0 0.0 14.1 6.7 18.0 80.6 0.9 12.1 0.3 0.3 2.5 14.9 0.0 0.1 10.3 0.6 0.3 6.5 22.7 0.1 0.0 0.0 0.0 0.0 178.4 0.4 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 859.6 0.0 0.2 1.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.3 0.0 0.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.2 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 3.2 0.5 0.0 0.0 11.5 0.6 19.3 0.0 1.4 0.3 0.3 0.8 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 37.0 2.8 3.7 1.0 0.0 0.0 0.1 0.2 0.2 32.0 0.0 32.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 1.3 0.0 0.0 10.7 75.3 0.9 0.7 10.6 0.0 0.1 1.6 0.0 0.0 0.1 0.2 0.0 0.7 0.0 0.3 0.0 0.0 0.7 0.4 6.6 2.4 4.2 16.8 1.6 0.0 7.1 0.5 1.0 0.0 0.2 0.3 CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.6;skin 1: 57.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.7;Basal respiratory cells: 23.7;Exocrine glandular cells: 54.1;Fibroblasts: 11.5;Suprabasal keratinocytes: 31.0" "Cancer enhanced" "Detected in many" "cervical cancer: 10.0;head and neck cancer: 9.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 140.1;hTERT-RPE1: 261.0;LHCN-M2: 284.2;U-2 OS: 151.0;U-87 MG: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021030 Approved Nucleoplasm,Centrosome,Cytosol "Secreted in other tissues" NA Yes 390000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Centrosome, Cytosol" "HPA021030: AB_1846010" "unprognostic (7.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.59e-3)" "unprognostic (3.63e-3)" "unprognostic (2.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.78e-2)" "unprognostic (4.36e-3)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (2.37e-3)" "unprognostic (6.49e-2)" "unprognostic (6.21e-10)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (1.31e-4)" 5.0 4.4 0.4 0.4 0.4 0.1 3.5 0.5 1.7 15.3 0.5 0.0 0.0 0.2 0.3 21.6 0.4 0.1 1.1 0.6 2.1 0.6 0.1 0.4 0.2 1.1 0.7 0.1 12.7 0.0 0.5 2.0 1.1 0.2 0.0 0.2 6.7 0.0 0.3 57.1 0.2 0.8 0.6 3.3 0.4 0.3 1.2 0.8 0.0 0.0 0.9 0.0 12.6 1.1 95.3 5.0 0.3 0.3 0.7 1.5 0.1 74.6 140.1 74.9 18.5 0.7 8.1 0.1 14.3 31.9 75.2 5.5 0.0 41.3 76.7 0.4 0.3 0.0 33.3 2.1 1.8 0.3 0.2 1.0 65.2 6.7 9.4 261.0 0.3 0.1 0.0 0.2 284.2 0.2 0.0 0.0 0.8 0.4 11.1 0.3 75.4 0.1 34.5 4.0 0.2 0.0 49.9 23.3 0.5 28.0 0.5 0.4 57.3 18.1 151.0 6.2 7.4 0.2 0.2 0.1 272.7 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.5 1.7 0.6 2.1 1.1 0.7 1.1 0.6 1.2 1.1 0.0 3.2 0.5 0.0 0.0 17.7 0.5 23.7 0.6 0.0 4.2 2.8 0.3 0.0 8.5 0.0 0.0 5.6 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.3 0.0 0.0 0.4 54.1 1.2 11.5 0.0 2.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.2 0.0 0.3 3.6 1.0 0.6 0.0 0.0 0.0 0.5 7.9 0.0 0.0 0.0 0.9 0.0 0.1 2.9 0.0 0.0 1.3 0.4 0.1 0.7 10.0 31.0 9.4 0.1 0.0 0.0 1.6 CRIP1 CRIP ENSG00000213145 "Cysteine rich protein 1" P50238 14 105486317-105488947 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 980.8;Endometrial ciliated cells: 1761.1;Proximal enterocytes: 2548.8;Respiratory ciliated cells: 1702.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 699.8;CAPAN-2: 415.5;HaCaT: 464.1;HDLM-2: 329.5;OE19: 1305.8;T-47d: 586.0" HPA042462 Approved Approved "Nuclear speckles,Plasma membrane,Centrosome,Cytosol" NA NA 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles, Cytosol" "Plasma membrane, Centrosome" "HPA042462: AB_10794277" "unprognostic (2.97e-3)" "unprognostic (1.27e-3)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.39e-1)" "unprognostic (2.93e-3)" "unprognostic (4.33e-1)" "unprognostic (3.33e-1)" "unprognostic (3.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.87e-1)" "unprognostic (9.16e-2)" "unprognostic (3.26e-3)" "unprognostic (5.10e-2)" "unprognostic (2.66e-1)" "unprognostic (7.51e-3)" "unprognostic (2.14e-1)" 265.2 21.7 19.2 61.1 19.7 29.4 180.8 20.0 36.4 147.4 20.3 133.9 121.7 108.0 206.6 118.7 118.2 28.1 262.6 18.5 20.3 109.7 17.8 254.6 83.9 26.9 29.1 49.8 18.3 21.2 41.5 28.3 24.6 49.6 55.4 0.2 135.7 87.9 44.7 301.1 312.5 42.4 24.7 94.5 94.2 14.3 21.0 79.6 182.1 50.2 135.7 113.7 98.9 20.3 0.0 699.8 4.8 0.6 12.1 8.3 66.8 1.3 0.4 9.0 0.1 21.0 415.5 228.0 2.4 191.0 2.6 464.1 0.1 0.0 0.0 329.5 0.0 17.7 294.7 116.3 1.8 0.1 0.2 3.8 0.0 23.1 0.0 0.9 0.5 64.6 0.5 0.9 0.0 3.7 8.1 1.6 7.4 1305.8 36.4 181.3 0.0 45.5 0.0 0.0 18.5 1.3 2.6 1.2 0.0 0.5 586.0 106.4 1.5 0.4 0.4 5.5 0.0 0.3 0.2 17.9 0.0 0.0 0.6 121.8 218.6 313.1 209.2 214.4 135.1 697.0 442.0 222.1 442.9 384.2 85.4 100.2 13.9 323.5 283.9 291.3 694.8 465.6 19.2 19.7 20.0 36.4 18.5 20.3 26.9 29.1 24.6 24.7 21.0 20.3 50.2 980.8 256.2 0.3 350.7 186.5 1.2 79.5 67.2 0.0 88.1 18.3 1.0 2.8 501.3 51.5 0.0 2.1 287.8 360.4 1.9 20.5 3.6 1761.1 124.5 86.4 76.5 27.3 0.0 3.1 4.3 313.3 210.0 491.9 521.5 0.1 24.7 1.3 52.2 0.0 0.0 243.1 30.5 168.0 577.3 26.2 25.1 523.7 370.0 1.9 461.4 0.2 83.4 0.0 0.1 34.2 659.2 9.4 584.3 0.7 2548.8 2.5 1702.1 0.0 223.5 8.2 448.0 1.0 11.4 29.4 251.6 1.5 524.7 0.1 190.7 3.0 CTDSPL "C3orf8, HYA22, PSR1, RBSP3, SCP3" ENSG00000144677 "CTD small phosphatase like" O15194 3 37861880-37984469 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 170.4;Excitatory neurons: 189.3;Inhibitory neurons: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 132.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048325 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA048325: AB_2680359" "unprognostic (7.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (6.48e-3)" "unprognostic (1.73e-1)" "unprognostic (3.35e-2)" "unprognostic (1.66e-3)" "unprognostic (4.30e-2)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-3)" "unprognostic (1.20e-1)" "prognostic favorable (6.22e-14)" "unprognostic (3.48e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" 21.1 9.2 19.4 6.3 20.6 10.0 28.1 24.3 23.2 20.3 17.1 33.4 14.3 20.2 14.0 23.8 17.9 29.3 29.4 18.8 17.3 39.7 21.5 27.2 4.1 19.2 17.7 19.6 15.8 12.0 10.7 31.7 16.6 26.5 30.2 3.2 27.1 31.3 21.2 52.9 17.6 23.2 18.1 17.3 31.7 10.6 19.5 7.2 14.0 19.9 5.5 26.4 19.1 17.3 44.5 18.9 7.6 24.0 29.2 41.0 57.2 30.0 37.0 20.1 23.5 27.4 35.3 0.2 17.9 36.9 8.4 36.3 19.2 56.1 16.0 0.1 15.1 27.2 18.8 63.1 26.4 0.0 6.4 21.5 132.3 21.2 25.5 22.4 28.2 12.0 8.9 0.0 33.7 13.7 11.1 0.1 31.5 17.7 2.7 12.3 14.9 0.2 63.3 28.7 6.3 19.9 16.5 28.7 33.5 30.5 28.1 7.3 23.2 14.4 20.4 27.3 19.1 0.6 0.2 0.2 15.8 14.8 27.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 2.1 19.4 20.6 24.3 23.2 18.8 17.3 19.2 17.7 16.6 18.1 19.5 17.3 26.8 67.3 27.6 170.4 1.2 30.1 17.0 17.7 27.9 10.1 25.7 59.4 42.2 65.8 25.7 23.9 0.0 34.7 1.0 35.6 23.5 14.2 21.5 7.6 17.6 22.4 45.2 7.8 189.3 4.7 9.9 32.4 10.2 27.2 1.3 15.7 22.9 18.1 7.2 10.1 126.3 18.5 2.0 13.3 6.5 51.3 71.7 11.3 8.8 22.5 1.4 9.5 1.0 87.4 48.8 14.2 17.9 98.2 0.4 15.5 9.1 19.7 12.4 1.7 26.3 55.4 40.4 10.0 16.9 17.7 28.7 9.4 2.0 65.8 42.0 14.4 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3435.4;Basal squamous epithelial cells: 3284.9;Breast myoepithelial cells: 1544.3;Fibroblasts: 2220.8;Glandular and luminal cells: 1201.1;Proximal tubular cells: 3662.8;Suprabasal keratinocytes: 2115.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HAP1: 61.6;hTCEpi: 79.9;RPTEC TERT1: 222.2;SuSa: 115.2;U-2 OS: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 33: Fibroblasts - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" 366.1 5.2 77.6 76.2 84.5 0.6 229.1 70.6 102.7 166.3 74.8 152.4 214.0 6.9 66.6 92.9 32.9 19.8 14.0 83.7 73.8 345.6 58.5 7.4 90.7 72.4 91.0 5.5 11.6 1.9 122.0 170.7 72.4 10.1 181.3 17.5 293.5 17.6 81.1 780.3 247.0 6.3 68.7 87.5 107.3 3.7 90.2 26.6 55.2 36.5 128.5 76.6 96.3 77.9 0.0 0.0 2.7 0.0 0.2 0.2 0.7 2.9 0.8 0.2 0.0 0.0 9.1 0.0 2.7 0.1 3.8 0.2 61.6 1.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 79.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 4.0 0.0 0.0 0.2 0.0 1.1 222.2 0.0 1.1 0.7 0.2 0.2 0.0 115.2 0.1 0.0 0.0 0.1 84.9 0.4 0.1 0.3 0.0 0.0 1.4 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 77.6 84.5 70.6 102.7 83.7 73.8 72.4 91.0 72.4 68.7 90.2 77.9 123.8 0.0 1.1 32.7 13.1 3435.4 14.4 276.9 3284.9 245.7 47.5 1544.3 4.1 0.0 5.1 283.3 0.0 35.9 6.1 0.0 563.4 0.0 0.8 45.0 140.8 45.9 0.0 0.0 1.0 0.0 25.4 2220.8 0.5 1201.1 0.0 0.0 43.5 0.2 63.6 6.7 150.8 0.0 240.1 0.9 887.9 1.3 20.8 35.3 439.4 8.4 0.0 6.7 0.0 4.5 4.2 0.1 0.0 0.4 13.3 10.6 0.0 3662.8 2.1 19.0 0.0 889.8 99.2 0.4 5.2 69.3 2115.0 77.2 43.4 0.3 0.1 9.3 CYB561D1 "FLJ39035, FLJ44753" ENSG00000174151 "Cytochrome b561 family member D1" Q8N8Q1 1 109494052-109502932 "Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027028 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA027028: AB_1847365" "unprognostic (2.15e-2)" "unprognostic (3.49e-1)" "unprognostic (1.04e-2)" "unprognostic (1.98e-1)" "unprognostic (2.27e-1)" "prognostic favorable (4.68e-4)" "unprognostic (4.53e-4)" "unprognostic (1.32e-1)" "unprognostic (3.45e-1)" "unprognostic (5.29e-2)" "prognostic favorable (5.16e-6)" "unprognostic (4.30e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.20e-3)" "unprognostic (2.75e-1)" "unprognostic (4.95e-3)" "unprognostic (5.82e-2)" 4.8 7.3 6.3 8.0 6.0 8.4 5.3 7.9 7.0 3.9 4.4 6.2 5.6 4.7 11.1 7.1 5.1 3.9 4.2 7.1 4.6 6.8 2.9 5.8 11.0 4.8 5.4 6.8 11.1 8.5 8.0 3.1 4.8 4.5 5.8 4.3 6.1 6.0 6.8 17.8 9.0 5.1 4.4 8.7 7.3 2.7 5.6 7.8 7.8 3.6 10.3 4.7 3.5 5.8 9.4 5.4 3.9 4.5 13.1 9.4 9.9 8.0 6.1 9.0 6.4 5.2 4.0 8.3 8.2 10.3 5.7 10.4 5.1 6.4 5.8 6.9 4.7 5.4 8.6 4.3 6.2 11.6 16.8 10.2 15.8 8.7 4.5 5.5 6.3 8.1 3.6 3.7 5.8 11.7 4.1 6.2 1.8 6.9 8.2 6.9 15.6 3.3 8.2 15.6 5.7 5.1 9.1 8.9 8.6 5.4 5.9 6.3 8.5 8.8 10.2 12.0 6.6 4.3 3.3 4.0 8.9 9.4 9.9 2.5 2.4 3.6 3.7 2.6 3.3 2.5 3.9 3.4 1.7 2.5 4.9 3.4 6.7 5.6 2.9 1.9 3.1 2.5 6.3 6.0 7.9 7.0 7.1 4.6 4.8 5.4 4.8 4.4 5.6 5.8 2.5 0.0 4.7 2.3 7.1 2.3 1.7 2.9 1.8 7.7 4.2 2.3 3.7 7.2 4.4 3.7 2.1 2.5 5.3 10.6 0.0 3.3 0.0 2.6 3.0 2.6 4.2 0.4 10.4 8.0 1.1 2.9 4.6 3.0 1.3 3.7 0.7 2.2 1.3 3.3 6.4 2.9 2.0 4.1 3.2 0.4 2.5 2.5 1.8 3.7 3.7 2.4 28.8 3.5 9.1 5.8 0.8 4.1 3.5 1.9 10.2 2.6 4.3 6.4 0.0 5.6 2.2 0.9 2.0 3.4 3.0 1.1 8.3 1.9 3.5 2.5 CYP27C1 FLJ16008 ENSG00000186684 "Cytochrome P450 family 27 subfamily C member 1" Q4G0S4 2 127183832-127220313 "Enzymes, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.1;skin 1: 5.1" "Cell type enhanced" "Detected in some" "Club cells: 5.4;Collecting duct cells: 3.7;Endometrial stromal cells: 5.8;Leydig cells: 7.5;Pancreatic endocrine cells: 7.6;Suprabasal keratinocytes: 7.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.6;HDLM-2: 11.8;hTERT-RPE1: 12.5;TIME: 11.6;U-138 MG: 10.9;U-251 MG: 7.9" "HPA062460, HPA068731" Enhanced Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA062460: AB_2732683, HPA068731: AB_2686023" "unprognostic (1.90e-1)" "unprognostic (4.07e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-2)" "unprognostic (3.03e-1)" "unprognostic (7.75e-3)" "unprognostic (3.48e-1)" "unprognostic (2.31e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.81e-3)" "unprognostic (1.11e-1)" "unprognostic (6.29e-4)" "unprognostic (3.49e-4)" "unprognostic (1.83e-1)" "unprognostic (4.27e-2)" "unprognostic (8.64e-2)" 0.6 0.5 0.8 0.4 0.2 0.3 0.3 0.8 0.7 4.1 0.6 1.2 0.3 0.6 0.4 1.6 0.6 0.7 0.9 0.5 1.0 0.2 0.2 0.2 0.3 0.6 2.4 0.2 0.2 0.0 0.1 0.1 0.4 0.9 0.3 0.1 0.3 0.7 0.4 5.1 0.6 0.2 0.3 0.2 0.3 0.3 2.7 0.0 0.1 0.1 0.8 1.8 2.5 0.8 1.3 3.4 1.9 0.1 0.1 0.0 0.1 0.4 3.2 1.8 0.8 0.1 2.8 0.1 0.1 2.0 1.3 7.6 2.7 1.4 0.6 11.8 1.4 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 1.1 12.5 0.4 0.3 0.0 0.2 2.1 0.2 0.3 0.1 4.0 0.0 1.0 0.1 0.2 0.0 5.9 1.0 0.1 0.7 4.9 0.0 0.0 1.5 0.1 0.2 11.6 10.9 2.0 5.3 7.9 0.1 0.1 0.0 0.1 0.1 0.9 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.8 0.2 0.8 0.7 0.5 1.0 0.6 2.4 0.4 0.3 2.7 0.8 0.2 0.0 0.6 0.0 0.2 1.8 1.2 2.1 0.0 0.0 1.5 0.3 0.5 0.0 5.4 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 5.8 0.5 0.0 0.0 0.6 0.2 0.0 2.4 0.0 0.5 0.0 0.2 0.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 1.9 0.1 7.5 0.2 0.0 0.0 0.1 0.0 0.0 0.5 0.2 7.6 0.0 0.4 0.0 1.6 0.0 0.0 0.2 0.0 0.0 1.5 1.0 0.1 0.7 0.0 7.2 0.0 0.2 0.0 0.0 2.9 CYP2W1 "FLJ20359, MGC34287" ENSG00000073067 "Cytochrome P450 family 2 subfamily W member 1" Q8TAV3 7 983181-989640 "Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 19.1;intestine: 6.1;skin 1: 10.5" "Cell type enriched" "Detected in some" 7 "Enteroendocrine cells: 98.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 25.3;stomach cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 13.5;Hep G2: 49.8" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.09e-3)" "unprognostic (1.94e-2)" "unprognostic (2.75e-2)" "unprognostic (1.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (6.26e-2)" "unprognostic (2.72e-5)" "unprognostic (7.52e-2)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.85e-4)" 0.1 19.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.4 0.0 0.9 6.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.3 1.0 0.1 2.1 0.5 0.2 0.3 0.2 0.0 10.5 1.0 0.0 0.0 0.4 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.2 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 2.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.6 4.3 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 4.0 2.3 1.5 0.0 0.6 0.0 0.0 0.5 0.0 2.6 0.0 0.0 1.1 0.0 3.7 0.0 0.1 0.1 0.1 0.0 0.3 98.5 0.0 0.0 0.9 0.6 10.2 0.0 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 13.6 0.0 0.0 0.9 0.0 1.8 0.3 0.0 0.0 0.1 10.5 0.0 0.0 0.0 0.1 3.3 0.0 0.1 1.2 1.1 0.0 3.3 0.6 0.0 0.8 0.3 0.2 0.1 0.0 4.4 1.9 0.2 4.4 11.4 3.7 CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;skin 1: 58.6;vagina: 22.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.8;Breast myoepithelial cells: 5.5;granulocytes: 7.0;Prostatic glandular cells: 4.0;Suprabasal keratinocytes: 3.0" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.1" "Group enriched" "Detected in many" 8 "monocytes: 14.1;T-cells: 4.3" "Cell line enhanced" "Detected in some" "MCF7: 1.7;T-47d: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" 1.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 10.5 0.0 0.0 0.2 0.3 0.0 18.8 0.1 0.1 0.0 0.0 0.0 0.0 7.0 0.3 0.3 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 3.2 6.4 0.2 58.6 0.1 0.0 0.0 0.3 1.4 1.0 0.0 0.1 0.0 0.0 1.7 6.3 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 6.1 4.3 0.0 0.5 1.5 0.2 0.0 0.0 0.4 0.0 1.1 14.1 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 8.8 5.5 0.4 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 7.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.4 0.0 0.3 0.0 0.0 0.5 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.8 0.0 3.0 0.0 1.8 0.0 0.0 0.3 DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 467.3;Suprabasal keratinocytes: 332.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Approved "Plasma membrane,Cytosol" NA NA 9700 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA026605: AB_1847464, HPA064789: AB_2685352" "unprognostic (2.81e-1)" "unprognostic (9.70e-2)" "unprognostic (3.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.01e-2)" "unprognostic (3.29e-1)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" 14.5 6.2 13.0 6.8 13.6 5.4 10.4 12.6 12.8 13.6 22.8 13.5 4.8 13.5 5.6 19.0 7.7 5.9 19.3 11.8 14.8 6.9 12.6 10.5 11.1 7.9 8.1 8.0 9.3 20.6 5.3 9.1 8.3 11.9 8.5 24.9 9.4 11.0 5.6 30.9 7.2 10.9 7.8 13.1 7.0 6.9 11.2 4.8 7.4 4.7 15.6 9.5 15.1 10.7 18.2 1.9 13.1 3.5 7.8 5.8 17.1 2.5 2.3 4.7 4.8 9.4 16.6 20.4 4.4 5.6 9.6 39.7 11.8 10.0 4.0 9.0 4.1 6.8 4.8 11.8 4.8 7.9 3.8 3.9 10.6 3.9 4.7 10.8 11.3 10.2 11.9 9.9 2.8 17.0 6.9 4.9 7.5 12.9 5.6 6.3 11.1 2.0 6.8 13.5 20.3 4.8 15.8 23.1 16.1 8.7 30.5 2.1 10.8 3.9 7.4 8.4 2.2 2.2 2.7 22.1 5.0 1.5 8.7 7.7 2.0 2.6 2.3 2.4 3.0 10.8 3.0 2.3 2.2 4.6 2.4 2.6 2.8 6.7 3.5 18.3 4.0 1.9 13.0 13.6 12.6 12.8 11.8 14.8 7.9 8.1 8.3 7.8 11.2 10.7 62.2 35.3 27.0 160.6 37.8 467.3 172.4 128.6 30.7 110.7 56.8 40.6 149.3 38.6 82.3 29.5 308.6 33.0 66.9 47.0 23.5 63.8 40.0 68.4 142.9 71.9 87.7 140.0 143.7 93.1 27.6 67.3 21.9 54.6 26.0 155.2 102.4 47.2 32.8 195.2 202.0 56.7 73.2 16.3 55.8 16.6 60.3 36.1 90.7 66.5 25.2 96.5 16.5 74.9 24.3 191.4 45.1 74.1 30.8 104.2 24.7 12.8 102.4 168.7 32.9 84.6 66.3 51.3 46.3 52.8 332.0 34.2 25.1 25.1 38.1 84.2 DDB2 "DDBB, FLJ34321, UV-DDB2, XPE" ENSG00000134574 "Damage specific DNA binding protein 2" Q92466 11 47214465-47239217 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;monocytes: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025912, HPA058406" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cell Junctions" "CAB025912: , HPA058406: AB_2683708" "prognostic favorable (7.29e-4)" "prognostic favorable (1.58e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.20e-4)" "unprognostic (4.29e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-2)" "unprognostic (6.18e-2)" "unprognostic (2.25e-1)" "unprognostic (3.58e-3)" "unprognostic (3.53e-1)" "unprognostic (1.94e-1)" "unprognostic (4.57e-3)" "unprognostic (1.21e-2)" "unprognostic (4.25e-2)" "unprognostic (9.82e-3)" "unprognostic (1.07e-1)" 13.2 22.5 2.6 8.2 3.2 11.6 13.5 3.4 3.6 12.5 3.4 12.8 7.6 12.7 11.7 24.8 17.6 12.5 6.8 2.5 2.4 4.4 27.0 12.2 14.7 3.4 2.7 11.6 14.4 4.8 4.7 6.8 3.5 9.7 14.9 2.3 14.4 11.7 6.2 46.7 10.2 13.9 2.7 11.3 9.5 4.5 3.2 23.5 5.5 6.9 17.0 11.2 14.1 3.6 23.7 62.3 25.9 19.3 16.6 32.7 29.9 26.0 58.8 32.0 37.1 10.1 14.1 56.6 5.3 23.2 23.6 40.8 14.6 51.8 15.7 14.5 27.5 13.3 55.7 46.7 15.8 15.9 34.4 43.4 58.0 15.9 35.2 10.2 94.2 14.7 3.5 27.0 52.7 44.4 60.4 7.7 8.4 31.1 22.3 30.3 5.6 30.6 13.5 22.7 13.2 16.7 31.2 8.7 8.1 30.8 56.1 5.5 41.2 96.8 44.1 21.3 12.6 27.6 22.4 12.5 37.0 20.2 35.9 9.8 12.8 20.2 19.3 18.4 18.8 18.3 20.1 18.8 10.4 14.5 14.8 15.7 3.7 14.1 15.8 0.3 47.7 15.9 2.6 3.2 3.4 3.6 2.5 2.4 3.4 2.7 3.5 2.7 3.2 3.6 13.8 16.0 22.2 7.8 25.1 38.9 39.7 28.1 75.1 5.0 18.0 25.8 7.8 11.5 16.3 5.5 10.4 3.6 21.3 11.1 9.8 12.5 1.5 5.2 8.1 19.5 7.7 19.1 6.6 13.8 9.0 16.0 18.3 9.5 22.8 31.2 15.0 16.6 17.5 1.7 1.4 12.6 16.2 17.5 12.8 2.1 19.0 16.8 19.6 24.4 135.5 9.6 35.0 1.0 10.6 19.9 9.8 10.5 34.1 8.9 15.7 7.7 13.9 12.8 0.0 12.1 14.0 3.1 8.6 34.5 30.3 1.5 34.3 25.4 16.5 26.5 DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100159645 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.0;intestine: 34.8;skin 1: 54.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 82.8;Paneth cells: 77.0;Proximal enterocytes: 298.9;Respiratory ciliated cells: 144.8;Squamous epithelial cells: 86.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 3.5;eosinophil: 6.6;memory B-cell: 10.9;naive B-cell: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 10.9;granulocytes: 6.6" "Group enriched" "Detected in some" 16 "OE19: 69.3;T-47d: 104.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli" "HPA046644: AB_2797231" "unprognostic (8.18e-2)" "unprognostic (3.83e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.94e-7)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "prognostic favorable (1.66e-4)" 0.4 0.1 6.4 1.0 7.2 0.2 6.1 18.3 7.1 4.8 3.6 8.9 24.7 3.3 0.5 37.0 2.0 6.5 0.2 5.1 4.5 10.8 0.9 1.6 0.6 5.9 5.3 1.0 6.9 0.4 3.3 0.4 6.0 2.3 4.5 0.2 8.6 2.1 0.3 54.2 34.8 0.5 4.8 0.8 20.1 1.1 5.3 0.1 2.4 0.0 1.8 6.5 10.1 4.9 0.0 0.3 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 2.4 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.3 0.0 0.0 0.0 0.0 1.1 1.6 0.0 0.0 4.2 0.4 0.3 0.1 69.3 0.0 0.4 0.0 3.6 0.0 1.6 5.2 0.1 0.0 3.1 0.0 0.1 104.4 1.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.5 0.4 6.6 1.6 0.0 0.0 10.9 0.1 0.7 0.7 6.8 0.0 1.0 0.2 0.2 0.0 0.1 0.0 0.7 6.4 7.2 18.3 7.1 5.1 4.5 5.9 5.3 6.0 4.8 5.3 4.9 0.7 3.2 5.0 5.2 3.7 1.8 3.3 22.9 1.2 4.6 24.2 15.2 0.6 37.1 34.8 82.8 0.0 7.7 3.3 24.2 1.9 19.0 1.2 15.3 4.3 3.8 55.3 1.3 0.5 1.5 4.9 1.3 54.6 28.9 9.5 0.9 0.4 0.3 1.6 0.0 0.4 53.5 34.6 0.9 0.6 1.6 0.3 1.5 0.0 3.7 0.5 1.2 12.3 0.0 1.5 2.4 77.0 0.0 3.7 1.7 298.9 0.4 144.8 22.0 0.0 1.1 3.1 3.2 4.0 86.9 15.3 37.4 2.5 0.2 69.6 21.0 DENND4C "bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF" ENSG00000137145 "DENN domain containing 4C" Q5VZ89 9 19230435-19374281 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 120.9;Oligodendrocyte precursor cells: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014917, HPA015096" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles, Cytosol" "HPA014917: AB_2261659, HPA015096: AB_1845831" "unprognostic (4.57e-2)" "unprognostic (1.73e-2)" "unprognostic (6.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.87e-2)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.51e-5)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" 21.7 11.9 5.9 9.2 7.0 10.6 21.7 14.1 6.3 17.2 8.0 17.4 25.1 17.2 14.3 14.5 16.4 13.8 14.5 5.3 5.6 13.9 15.2 18.0 11.8 5.9 5.7 21.4 12.9 19.0 8.7 19.6 5.7 16.1 19.8 11.8 15.1 13.4 10.6 29.6 22.4 14.6 5.8 12.7 19.8 11.2 7.2 17.7 17.3 12.4 11.2 16.6 16.0 6.6 17.7 17.5 11.7 15.3 26.6 28.5 21.4 10.0 14.9 10.2 13.7 8.4 11.6 7.5 8.3 13.6 11.8 9.4 13.7 9.4 12.0 47.2 7.8 34.4 18.5 10.4 13.4 8.3 18.8 11.7 18.7 9.0 15.5 21.6 20.2 9.9 9.4 8.5 13.1 7.4 13.8 18.8 9.0 24.7 8.5 12.6 6.6 10.9 29.2 34.1 10.9 8.5 8.4 20.1 7.4 11.0 12.1 11.3 18.5 8.9 5.2 10.0 10.5 5.8 14.9 4.0 7.7 7.6 5.2 8.3 1.6 1.9 5.4 0.8 7.0 1.7 4.6 5.5 3.1 2.3 4.3 5.0 0.9 6.4 0.9 3.2 3.8 2.4 5.9 7.0 14.1 6.3 5.3 5.6 5.9 5.7 5.7 5.8 7.2 6.6 28.6 9.6 11.5 85.8 21.3 51.2 16.7 18.0 65.4 20.9 16.0 11.0 12.4 14.3 21.6 16.5 60.5 29.4 22.6 26.6 1.9 9.8 7.7 12.7 15.5 22.9 19.8 9.7 78.6 12.5 13.5 24.0 47.4 20.4 27.1 24.8 51.0 11.5 19.0 23.5 87.2 22.6 24.4 23.9 22.0 5.2 18.6 32.2 21.4 120.9 8.5 13.6 27.8 107.1 69.1 12.1 20.9 20.3 14.1 19.4 26.4 4.9 21.6 16.3 0.0 19.5 16.2 3.3 6.8 30.9 49.3 16.1 28.2 12.0 23.3 23.2 DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 99.2;skin 1: 372.6" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 500.7;Basal squamous epithelial cells: 214.5;Squamous epithelial cells: 419.6;Suprabasal keratinocytes: 688.8" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 246.2;HBEC3-KT: 54.6;hTCEpi: 156.7;hTERT-HME1: 103.6;REH: 44.8" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" 4.8 0.1 0.1 0.5 0.0 0.2 12.5 0.1 0.0 23.8 0.0 0.3 0.4 0.1 1.2 99.2 1.3 0.0 0.4 0.1 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.4 0.2 3.4 0.2 12.5 0.0 6.0 0.1 0.1 19.6 1.3 1.0 372.6 0.3 0.5 0.0 0.0 0.1 0.1 0.0 7.7 0.1 0.0 24.7 3.5 48.5 0.0 17.2 1.8 0.2 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 246.2 0.0 54.6 0.0 0.1 14.6 0.9 4.7 0.4 9.7 0.1 0.2 10.2 156.7 0.0 103.6 19.6 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.9 0.1 21.8 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.1 0.3 0.0 500.7 62.0 49.5 214.5 0.0 3.1 8.0 1.3 0.0 30.3 0.0 0.0 73.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.3 2.4 0.0 0.3 0.0 14.2 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.3 0.0 0.3 0.2 12.2 0.0 34.8 0.0 0.0 0.6 39.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.2 32.1 0.0 0.1 10.2 0.0 0.0 0.0 3.4 0.1 0.1 419.6 688.8 25.0 2.3 0.0 0.1 89.1 DSG4 "CDHF13, LAH" ENSG00000175065 "Desmoglein 4" Q86SJ6 18 31376777-31414912 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skin 1: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Squamous epithelial cells: 1.0;Urothelial cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 133 "HaCaT: 37.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059456, HPA079244" Enhanced NA NA 320000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA059456: AB_2684025, HPA079244: " "unprognostic (9.86e-2)" "unprognostic (8.61e-2)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "unprognostic (5.55e-2)" "unprognostic (5.61e-2)" "unprognostic (2.11e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-1)" "unprognostic (2.58e-1)" "unprognostic (2.14e-1)" "unprognostic (1.79e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.0 0.0 0.0 0.0 0.0 0.2 1.3 DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 902.0;Cardiomyocytes: 729.7;Squamous epithelial cells: 1657.5;Suprabasal keratinocytes: 2018.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 278.0;HaCaT: 302.6;HBEC3-KT: 217.5;hTCEpi: 666.3;SuSa: 204.1" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" 5.2 11.6 4.2 7.0 1.8 0.6 65.8 2.5 3.5 151.0 19.3 46.0 52.0 5.4 27.5 460.7 16.3 7.8 84.9 3.4 0.9 22.4 41.9 6.1 3.7 1.6 2.0 2.0 111.5 54.9 9.0 63.3 1.5 29.9 43.5 21.2 125.1 11.7 3.4 854.8 42.3 2.9 2.4 3.2 48.1 1.5 2.2 37.1 41.5 0.6 78.7 13.1 286.1 0.9 132.2 38.9 0.0 0.1 5.6 8.2 278.0 25.5 21.8 12.4 12.0 110.8 33.5 0.1 35.8 40.9 10.0 302.6 46.1 217.5 2.2 0.1 54.1 0.0 21.5 149.5 0.0 0.6 0.9 1.9 666.3 11.0 121.7 30.0 0.0 0.6 0.2 0.2 22.0 61.4 0.1 1.0 5.6 62.6 19.6 0.1 0.1 32.9 45.3 34.8 12.6 0.3 28.5 59.9 0.2 204.1 71.0 0.3 0.0 4.8 1.2 0.3 0.3 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.8 2.5 3.5 3.4 0.9 1.6 2.0 1.5 2.4 2.2 0.9 7.6 51.3 17.0 0.0 7.5 902.0 164.5 157.3 278.3 4.4 184.5 126.4 729.7 97.2 197.5 60.7 14.6 273.0 1.2 357.1 1.9 160.6 1.8 306.5 42.4 46.9 174.6 0.0 0.1 111.9 273.1 51.2 237.0 560.1 3.8 532.2 4.6 186.6 27.5 0.0 0.9 204.7 111.9 1.9 77.8 1.3 0.9 5.9 101.4 3.7 2.6 14.7 0.0 0.0 0.1 167.4 284.2 0.0 5.7 204.0 180.7 12.0 176.6 28.6 0.0 0.4 67.4 1.3 2.7 1657.5 2018.0 385.7 8.1 0.3 247.8 269.9 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768096-172771195 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 2357.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 7426.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 7426.8" "Cell line enhanced" "Detected in all" "HHSteC: 201.0;hTCEpi: 359.3;REH: 202.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Nucleoli Cytosol "HPA069577: AB_2686156" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 922.6 515.4 84.9 364.9 85.8 692.4 586.1 134.8 121.1 501.3 134.7 336.1 66.0 382.3 42.0 526.6 677.4 570.5 395.3 79.4 114.6 281.2 721.3 719.9 178.6 132.0 90.3 541.2 240.1 116.5 319.5 297.3 104.1 438.5 228.5 202.7 350.3 356.9 251.8 1054.1 170.3 452.7 123.7 304.7 396.0 68.1 115.4 131.3 612.9 451.3 56.2 778.1 610.0 121.2 10.7 26.5 8.2 11.5 175.6 102.2 14.0 170.3 49.3 111.9 45.0 29.2 12.4 3.5 48.6 120.4 128.1 4.7 8.1 42.3 52.1 95.8 22.4 2.3 63.1 12.6 201.0 1.2 3.8 98.1 359.3 50.9 82.1 58.2 35.6 7.4 9.0 66.1 73.1 12.6 5.7 5.0 7.4 8.2 7.7 202.2 15.3 32.3 80.2 5.4 35.5 14.9 46.2 76.9 6.3 34.1 6.7 1.9 94.1 79.1 39.8 77.8 13.4 13.6 8.4 3.1 70.3 1.8 3.3 931.4 584.5 1640.7 85.0 589.2 212.6 57.6 75.6 88.6 263.4 54.1 35.9 40.7 7426.8 114.5 791.6 14.3 68.1 409.9 84.9 85.8 134.8 121.1 79.4 114.6 132.0 90.3 104.1 123.7 115.4 121.2 1856.5 410.3 341.0 23.8 918.4 1279.8 1140.5 456.9 1810.4 73.0 464.2 567.7 211.3 739.2 243.1 211.5 27.1 316.2 618.9 633.7 56.7 335.9 71.6 531.6 990.9 870.4 715.5 193.5 11.9 88.7 407.2 1367.4 597.3 1013.7 301.1 175.8 781.4 345.7 1043.0 48.8 13.4 891.8 207.5 1525.5 2357.3 40.3 384.9 1965.5 542.5 66.5 173.3 1159.3 33.0 6.6 4.1 226.3 683.3 311.1 952.2 685.7 736.1 35.5 218.0 190.5 769.2 720.7 671.9 12.9 24.6 1996.9 1956.6 582.0 1015.2 223.4 415.8 676.6 EDARADD ENSG00000186197 "EDAR associated death domain" Q8WWZ3 1 236348257-236502915 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 8.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.7;granulocytes: 22.7;Syncytiotrophoblasts: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 49.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 15.9;HDLM-2: 13.2;HMC-1: 52.7;RT4: 45.3;T-47d: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018836 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA018836: AB_1847984" "unprognostic (3.74e-1)" "unprognostic (3.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.12e-2)" "unprognostic (2.06e-3)" "unprognostic (3.12e-3)" "unprognostic (9.94e-2)" "unprognostic (2.96e-2)" "unprognostic (2.62e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (2.57e-2)" "unprognostic (5.72e-2)" "unprognostic (3.00e-1)" "unprognostic (2.47e-1)" "unprognostic (1.90e-2)" "unprognostic (9.62e-3)" 0.4 0.1 0.2 0.4 0.1 0.4 4.8 0.1 0.1 0.7 0.0 0.3 0.4 0.4 5.2 3.3 1.2 0.8 0.9 0.1 0.1 1.1 0.3 0.7 1.2 0.2 0.2 0.4 3.8 0.1 0.1 4.9 0.1 3.6 0.3 0.0 1.4 6.1 0.0 5.8 0.3 0.1 0.1 1.2 6.3 3.4 0.2 2.3 6.4 0.0 2.6 8.7 1.0 0.1 0.0 3.8 0.3 0.0 0.0 0.0 15.9 0.0 0.0 1.3 0.8 1.0 0.0 0.0 0.0 0.2 4.3 8.8 6.5 9.6 1.2 13.2 7.6 0.1 0.1 1.4 0.0 0.4 52.7 0.0 2.7 0.9 0.8 0.0 0.0 1.8 0.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 3.4 0.1 0.0 0.0 45.3 0.4 0.3 0.0 1.2 0.2 0.3 12.6 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 49.5 0.3 0.1 3.1 0.4 4.1 0.1 4.7 6.1 0.5 0.2 0.4 3.2 0.3 5.3 0.2 0.1 5.1 2.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.0 1.3 0.0 0.4 6.9 7.3 16.3 13.1 0.0 7.1 7.4 4.1 5.7 8.4 0.0 0.0 26.7 3.0 0.1 3.9 1.7 10.6 0.2 1.2 1.2 0.0 2.5 0.5 0.9 14.2 1.1 5.1 0.4 22.7 2.8 5.0 0.5 3.4 0.0 0.6 0.1 8.2 1.5 8.9 9.3 0.3 0.6 12.4 1.0 3.7 0.6 0.0 1.0 0.4 0.6 0.0 0.4 1.8 4.2 0.1 0.4 3.2 0.1 0.0 1.4 6.1 13.4 3.7 6.5 5.3 22.6 6.2 0.3 0.0 5.3 EEF2K "CaMKIII, eEF-2K" ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206278-22288738 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 49.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 69.1;Late spermatids: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.5;HL-60: 1.6;HMC-1: 1.8;NB-4: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB007818: AB_598150, HPA056061: AB_2683021" "unprognostic (4.79e-2)" "unprognostic (6.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.94e-2)" "unprognostic (5.09e-3)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.74e-1)" "unprognostic (8.50e-2)" "unprognostic (2.01e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 19.8 7.1 1.0 0.4 0.9 0.7 15.9 1.5 2.2 17.2 0.7 20.1 0.3 14.3 0.7 9.1 13.1 0.3 9.2 0.9 1.2 3.6 7.8 9.0 0.5 1.1 0.9 8.2 12.9 0.0 5.2 0.4 1.2 19.6 0.2 0.3 15.0 0.2 24.9 49.0 8.1 0.3 0.9 8.0 9.8 2.3 1.4 0.0 6.3 0.0 0.2 18.8 15.4 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 1.5 0.2 0.0 0.0 0.1 0.0 0.6 0.2 1.0 0.0 1.6 1.8 0.0 0.4 0.1 0.1 0.3 0.1 0.1 0.2 1.3 0.0 0.0 0.1 1.6 0.1 0.4 0.0 0.4 1.0 0.2 0.4 0.0 0.3 0.6 0.0 0.0 0.2 0.1 0.2 0.5 0.5 0.7 0.3 1.4 0.0 0.3 0.1 0.3 1.0 1.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.4 0.1 0.0 1.0 0.9 1.5 2.2 0.9 1.2 1.1 0.9 1.2 0.9 1.4 1.1 43.7 22.4 13.3 22.5 7.3 12.6 9.6 3.9 31.3 69.1 15.4 9.3 17.3 12.8 9.8 9.2 14.6 16.3 12.7 24.2 0.0 4.9 42.9 42.4 12.6 18.4 3.0 7.6 21.2 13.4 11.7 19.2 26.0 34.9 29.2 12.0 22.5 17.7 18.7 1.7 37.4 12.3 4.1 15.3 16.2 76.6 14.3 8.7 8.8 15.9 7.9 6.1 6.2 31.7 8.6 10.2 26.3 15.8 19.6 6.6 12.5 4.0 14.9 21.6 6.6 43.5 10.0 1.3 4.2 16.9 23.0 7.8 7.8 5.7 8.1 6.7 EFNA4 "EPLG4, LERK4" ENSG00000243364 "Ephrin A4" P52798 1 155063737-155069553 "Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 30.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.1;Theca cells: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB021350 Uncertain "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB021350: " "unprognostic (4.65e-2)" "unprognostic (8.07e-2)" "unprognostic (3.43e-2)" "unprognostic (7.04e-2)" "unprognostic (7.91e-2)" "unprognostic (4.81e-1)" "prognostic unfavorable (1.00e-5)" "unprognostic (1.37e-2)" "unprognostic (3.89e-2)" "unprognostic (6.17e-2)" "unprognostic (2.87e-2)" "unprognostic (7.97e-3)" "prognostic unfavorable (3.14e-4)" "prognostic favorable (3.60e-5)" "unprognostic (3.35e-2)" "unprognostic (1.97e-1)" "unprognostic (6.29e-2)" 3.7 12.0 3.2 4.5 3.3 1.3 9.4 3.3 3.4 11.1 4.5 11.7 10.5 6.5 12.4 18.6 4.9 5.2 3.5 3.3 3.0 6.9 8.3 4.5 5.1 3.6 3.4 9.9 5.7 7.9 2.5 4.5 3.5 9.1 12.1 0.9 13.1 4.3 1.3 30.2 10.7 4.3 3.4 6.5 5.9 2.3 3.3 3.8 6.2 1.8 7.3 4.8 14.2 3.5 11.4 8.5 20.4 30.4 11.8 7.5 17.0 5.1 9.6 9.7 9.0 12.5 18.5 14.6 28.2 5.1 7.7 26.2 12.3 7.6 3.9 6.9 3.7 1.4 7.7 17.8 4.3 3.3 22.0 4.5 23.2 4.9 5.7 8.4 19.7 11.9 6.2 9.5 5.5 25.2 7.5 8.3 37.6 43.3 17.5 26.0 8.1 14.3 15.2 9.6 4.9 22.3 10.1 37.1 4.5 14.7 24.3 10.2 10.2 5.8 17.0 11.7 7.8 9.7 11.0 14.6 5.5 7.8 5.9 0.1 10.1 7.3 7.7 9.2 8.0 22.9 8.5 8.8 8.3 17.3 11.8 8.1 10.9 3.9 13.7 25.2 8.9 6.6 3.2 3.3 3.3 3.4 3.3 3.0 3.6 3.4 3.5 3.4 3.3 3.5 2.5 0.0 6.3 2.0 9.0 25.1 8.6 21.2 19.4 0.2 20.7 15.6 1.3 8.6 12.1 16.5 0.0 9.2 12.3 23.9 1.9 32.4 0.1 4.9 4.5 6.8 3.0 2.1 0.2 14.0 86.1 8.4 3.6 6.6 1.3 15.6 5.7 3.6 12.8 0.0 0.2 18.7 8.2 6.3 6.8 0.4 7.8 5.3 17.8 1.0 5.9 5.6 4.1 0.0 0.8 21.5 37.0 5.7 2.2 21.2 38.3 4.4 6.5 0.2 0.0 1.7 6.0 0.5 4.1 15.4 32.7 9.9 7.2 73.3 28.3 10.8 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EGR3 PILOT ENSG00000179388 "Early growth response 3" Q06889 8 22687659-22693480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.2;skin 1: 45.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 284.3;Glandular and luminal cells: 116.6;granulocytes: 108.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 47.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.5;HMC-1: 9.5;MCF7: 31.9;SK-MEL-30: 22.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 19.3;basal ganglia: 52.5;cerebral cortex: 47.8;hippocampal formation: 41.3;olfactory bulb: 33.7" "HPA006206, CAB009373" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB009373: AB_2097202, HPA006206: AB_10602491" "prognostic favorable (1.83e-4)" "unprognostic (1.15e-1)" "unprognostic (2.40e-1)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "unprognostic (4.07e-2)" "unprognostic (1.00e-1)" "unprognostic (6.44e-2)" "prognostic favorable (4.78e-4)" "unprognostic (3.48e-2)" "unprognostic (5.14e-2)" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.11e-2)" "unprognostic (4.72e-2)" "unprognostic (2.35e-2)" "unprognostic (1.07e-2)" 29.0 24.5 7.7 19.0 9.9 10.1 10.3 0.6 47.2 9.5 0.0 4.6 1.5 5.6 0.4 5.9 17.3 30.0 12.1 16.1 0.0 5.8 2.9 5.8 11.4 5.1 0.0 15.3 4.5 13.8 6.8 1.0 2.0 14.4 3.2 4.5 3.1 0.9 1.9 45.6 3.9 12.5 1.3 3.3 6.5 5.4 0.0 19.5 8.4 3.2 5.9 14.8 3.6 5.8 0.2 0.0 0.2 0.3 1.8 5.5 0.1 0.6 0.6 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.4 0.5 0.2 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.5 0.6 0.2 0.2 0.0 0.8 0.1 0.2 0.3 0.1 0.0 31.9 0.0 0.2 0.1 2.2 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.5 0.0 22.5 0.3 1.4 0.1 0.0 0.3 0.1 0.2 0.4 0.4 0.1 0.0 0.9 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.7 9.9 0.6 47.2 16.1 0.0 5.1 0.0 2.0 1.3 0.0 5.8 80.2 6.4 11.2 0.3 46.7 23.1 31.9 43.8 39.3 2.3 73.0 68.2 47.1 0.0 12.2 0.0 0.0 1.3 9.3 3.5 0.0 3.3 18.4 47.1 52.7 36.5 284.3 0.0 16.0 4.2 1.3 33.9 35.2 116.6 108.7 21.8 37.5 0.5 4.7 0.0 0.9 19.2 8.2 19.0 20.3 11.6 3.1 27.8 21.4 3.7 0.0 5.1 0.0 1.0 0.7 4.5 2.2 0.4 3.7 16.1 0.2 0.1 5.7 1.3 0.0 41.3 35.9 0.3 0.2 16.5 50.0 9.7 11.5 6.5 7.0 9.8 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561785-184582408 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 38.1;Breast myoepithelial cells: 50.8;Enteroendocrine cells: 71.5;Intestinal goblet cells: 43.3;Squamous epithelial cells: 44.3;Undifferentiated cells: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 28.8;HaCaT: 40.2;OE19: 28.3;SK-BR-3: 30.9;T-47d: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.7 0.7 3.0 3.7 2.7 0.1 10.4 5.8 4.1 22.7 1.0 10.3 6.4 10.1 1.8 30.6 4.0 2.8 1.9 2.9 2.4 5.8 0.9 3.4 0.9 5.7 3.4 8.3 14.9 1.1 2.0 5.7 6.1 10.0 10.9 0.5 31.7 3.5 0.5 51.5 6.3 3.8 2.3 1.0 22.8 0.9 4.0 0.7 0.9 0.4 2.4 4.0 20.9 2.7 6.6 2.3 14.8 1.6 4.5 0.3 28.8 1.1 1.9 2.2 1.2 2.0 0.2 0.0 2.8 6.3 1.0 40.2 5.4 1.9 0.6 0.2 1.1 0.0 0.3 0.0 0.3 0.0 0.2 1.2 13.0 1.8 0.2 0.7 0.0 0.0 0.0 0.0 1.0 17.6 0.0 6.4 1.4 28.3 2.5 1.5 9.0 0.0 0.0 5.8 1.9 2.2 1.2 30.9 1.3 7.8 20.5 0.1 0.0 3.6 5.1 1.8 2.5 0.0 0.0 0.1 0.3 0.0 14.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 5.8 4.1 2.9 2.4 5.7 3.4 6.1 2.3 4.0 2.7 0.9 3.2 2.7 11.1 0.2 24.1 7.6 5.3 17.1 0.9 38.1 50.8 1.8 2.8 4.6 0.0 0.0 10.1 1.1 21.5 1.9 0.5 0.6 3.7 4.0 1.4 71.5 0.0 4.6 1.6 18.7 6.9 27.0 7.5 4.5 2.1 1.8 0.0 23.5 15.2 5.8 43.3 10.2 0.3 9.8 0.4 2.8 2.4 0.0 1.0 0.8 0.1 0.0 5.0 0.3 3.2 7.2 6.0 0.0 6.0 1.7 0.2 1.4 1.0 0.0 4.5 2.9 0.4 0.6 44.3 35.8 16.3 0.8 1.6 55.0 20.7 ETV3 PE-1 ENSG00000117036 "ETS variant transcription factor 3" P41162 1 157121191-157138474 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 361.2;monocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004794, HPA073211" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA004794: AB_1078761, HPA073211: " "unprognostic (1.65e-1)" "unprognostic (2.37e-1)" "unprognostic (3.78e-2)" "unprognostic (4.39e-2)" "unprognostic (7.59e-2)" "unprognostic (5.23e-2)" "unprognostic (1.38e-2)" "unprognostic (3.30e-1)" "unprognostic (2.36e-2)" "unprognostic (5.37e-2)" "unprognostic (1.34e-2)" "unprognostic (8.02e-2)" "unprognostic (7.26e-3)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" "unprognostic (8.97e-2)" "unprognostic (6.65e-2)" 13.7 7.7 6.6 11.1 6.6 24.0 12.1 7.9 20.1 8.3 5.3 8.7 15.1 9.3 7.5 15.6 7.8 12.7 7.4 8.3 8.1 6.6 6.6 12.6 10.1 7.7 6.5 11.5 6.4 23.9 5.0 12.8 7.0 10.2 9.5 5.7 9.2 8.5 9.4 31.5 14.6 10.1 7.1 10.0 10.0 9.4 7.4 10.8 7.9 8.8 12.5 17.6 11.4 7.1 11.9 11.4 11.6 10.1 17.3 11.3 9.9 10.9 11.4 10.5 9.7 12.2 11.6 14.2 13.4 13.4 5.6 18.0 12.8 16.7 13.8 31.0 8.1 11.9 12.2 6.7 10.3 19.0 18.1 12.5 19.2 15.7 13.3 8.5 11.1 8.8 13.9 10.2 12.0 15.7 5.8 10.7 38.6 16.9 8.7 8.7 13.8 16.3 8.1 43.9 9.8 19.0 11.9 28.1 29.5 20.7 14.4 20.7 18.8 13.5 11.9 13.2 13.7 24.6 13.5 16.7 15.5 10.9 45.2 6.3 4.6 3.3 4.5 4.2 6.2 2.1 3.9 4.5 4.5 2.4 3.9 3.5 5.4 4.2 4.2 1.2 3.3 2.6 6.6 6.6 7.9 20.1 8.3 8.1 7.7 6.5 7.0 7.1 7.4 7.1 22.9 35.3 16.2 3.6 20.4 70.4 18.4 20.2 71.7 2.3 18.2 14.4 9.4 5.7 24.3 12.9 10.4 7.5 37.2 22.1 0.0 6.4 9.4 18.1 18.0 19.4 10.7 5.9 8.1 6.3 9.0 16.3 15.3 29.5 22.2 6.4 15.4 8.3 8.7 1.7 6.9 12.5 10.2 13.2 361.2 7.3 4.1 69.0 16.0 5.6 97.0 3.9 10.3 6.0 4.4 10.4 13.4 4.5 25.3 16.5 16.0 3.2 29.7 6.3 13.1 16.4 15.4 10.2 9.4 64.2 78.7 14.9 40.4 6.0 14.4 51.4 ETV7 "TEL-2, TEL2" ENSG00000010030 "ETS variant transcription factor 7" Q9Y603 6 36354091-36387800 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.0;skin 1: 15.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Cytotrophoblasts: 28.8;Exocrine glandular cells: 23.8;Proximal enterocytes: 21.5;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9;T-reg: 16.3" "Group enriched" "Detected in many" 4 "granulocytes: 18.9;monocytes: 5.7;T-cells: 16.3" "Cell line enhanced" "Detected in some" "BEWO: 27.1;BJ hTERT+ SV40 Large T+: 14.7;BJ hTERT+ SV40 Large T+ RasG12V: 27.8;HDLM-2: 59.7" "Low region specificity" "Detected in all" HPA029033 Uncertain Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA029033: AB_10601375" "unprognostic (1.67e-2)" "prognostic favorable (5.16e-4)" "unprognostic (9.48e-2)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" "unprognostic (2.62e-3)" "unprognostic (9.08e-2)" "unprognostic (4.11e-2)" "unprognostic (2.08e-2)" "prognostic favorable (5.32e-4)" "unprognostic (6.81e-3)" "unprognostic (1.11e-1)" "unprognostic (1.69e-3)" "unprognostic (5.54e-2)" "unprognostic (4.93e-1)" "unprognostic (1.27e-2)" "prognostic favorable (2.95e-6)" 1.9 2.1 1.5 6.9 1.5 0.9 2.1 1.0 1.7 2.1 1.4 3.3 16.0 1.0 1.3 3.6 2.2 3.4 0.4 1.5 1.4 2.3 2.9 4.9 5.3 2.2 1.2 1.5 1.6 2.2 3.8 3.6 2.1 2.9 2.6 0.4 8.6 1.5 0.2 15.4 12.7 1.0 2.1 3.1 6.2 1.1 1.4 4.0 1.2 0.3 3.9 5.5 2.5 1.4 3.2 0.0 0.2 0.1 0.0 0.2 27.1 0.0 9.2 14.7 27.8 0.5 6.2 0.1 0.7 0.2 2.3 3.3 0.4 1.7 0.7 59.7 0.5 0.5 0.0 0.0 1.8 0.0 0.3 1.2 2.4 0.7 0.2 0.0 0.4 0.0 0.1 0.2 0.3 0.1 0.2 0.3 0.2 0.3 0.1 6.1 0.1 0.2 0.2 1.1 0.8 0.0 0.6 2.1 0.5 0.0 3.1 0.6 0.2 0.3 0.7 0.3 0.1 0.1 0.1 0.2 0.0 2.7 0.4 0.0 3.7 0.3 1.6 5.7 3.9 3.3 5.4 2.2 0.9 2.4 1.0 1.4 18.9 0.6 1.9 0.0 16.3 2.5 1.5 1.5 1.0 1.7 1.5 1.4 2.2 1.2 2.1 2.1 1.4 1.4 1.4 19.2 14.8 0.3 1.2 2.0 2.2 8.0 6.2 0.2 2.5 2.7 0.5 7.2 7.1 0.0 0.0 28.8 0.7 6.6 0.0 12.4 0.4 0.4 1.4 1.1 3.6 0.0 0.5 23.8 6.6 2.7 8.2 0.7 2.5 1.7 0.0 0.4 2.9 0.0 0.3 6.5 6.1 1.3 1.6 0.5 1.5 1.0 3.6 0.0 6.5 3.1 1.0 0.0 0.3 13.4 7.8 1.2 5.6 4.8 21.5 1.3 3.0 0.6 0.0 1.0 5.5 0.9 26.8 6.4 3.7 8.5 3.6 0.7 7.6 4.8 FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 71.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 71.7;Extravillous trophoblasts: 138.2;Langerhans cells: 74.2;Macrophages: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 543.5;eosinophil: 163.4;intermediate monocyte: 160.6;non-classical monocyte: 248.6" "Group enriched" "Detected in all" 9 "granulocytes: 543.5;monocytes: 248.6" "Cell line enhanced" "Detected in all" "SK-BR-3: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" 4.2 5.5 4.2 5.9 5.2 8.8 9.0 3.1 3.6 10.1 3.9 5.5 10.0 2.5 4.7 39.3 2.5 2.3 4.0 2.8 3.4 8.8 3.6 12.3 6.7 5.5 5.3 2.8 5.5 11.0 7.9 6.6 5.6 19.3 3.2 1.2 18.4 3.6 4.0 71.2 9.7 1.1 3.3 23.4 6.1 3.7 6.6 6.9 7.6 0.6 7.8 9.2 18.4 3.6 27.7 7.3 4.1 7.6 4.4 1.9 27.8 8.5 4.7 5.3 4.7 16.0 16.9 8.9 3.7 5.3 7.6 43.7 3.3 22.2 4.4 7.3 2.3 18.6 4.9 4.2 2.0 5.1 6.3 1.2 27.1 7.3 7.1 1.6 3.6 8.1 10.2 21.5 4.9 16.4 14.3 13.8 5.3 17.7 12.3 14.1 7.0 11.7 4.1 19.6 7.7 9.1 7.4 84.0 3.8 1.7 34.9 7.5 4.8 12.6 9.1 11.5 9.6 7.8 7.3 3.8 2.0 13.2 9.2 543.5 28.3 163.4 13.2 160.6 11.7 7.0 23.7 27.2 36.2 11.7 28.1 27.9 15.3 6.9 248.6 3.9 43.0 24.2 4.2 5.2 3.1 3.6 2.8 3.4 5.5 5.3 5.6 3.3 6.6 3.6 3.5 0.0 7.0 0.0 18.5 32.6 17.0 31.6 71.7 0.3 26.7 20.1 2.9 7.2 15.7 11.0 0.0 41.5 24.3 5.1 1.9 10.1 9.9 3.0 1.7 8.0 10.8 16.2 0.5 6.0 138.2 3.6 5.1 5.2 51.5 1.4 17.2 0.7 20.0 5.0 0.4 8.8 16.2 36.7 74.2 24.3 3.4 70.0 7.2 1.9 29.9 0.3 25.7 0.5 0.1 13.4 7.8 1.9 3.5 20.9 16.1 2.4 7.4 2.6 6.6 1.1 4.3 3.4 4.9 57.7 36.8 31.3 26.1 14.2 10.4 24.6 FAM25G bA301J7.4 ENSG00000189090 "Family with sequence similarity 25 member G" B3EWG6 10 47487219-47491693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 18.6;skin 1: 43.3" "Group enriched" "Detected in some" 4 "Pancreatic endocrine cells: 57.1;Spermatogonia: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SK-BR-3: 13.8" HPA044808 Uncertain NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA044808: AB_2679096" "unprognostic (1.97e-2)" 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.4 10.4 0.0 0.2 0.2 0.0 0.0 18.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 0.7 43.3 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 10.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 3.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.1 0.1 0.0 0.0 0.0 7.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 19.8 3.9 0.0 0.4 0.0 0.0 0.1 0.1 FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.5;skin 1: 25.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.8;Basal prostatic cells: 32.5;Basal squamous epithelial cells: 43.3;Squamous epithelial cells: 31.9;Suprabasal keratinocytes: 41.1;Urothelial cells: 25.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.3;HaCaT: 18.1;HBEC3-KT: 9.8;hTCEpi: 19.7;hTERT-HME1: 23.8;RT4: 19.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "HPA031464: AB_10599973, HPA031465: AB_10601566" "unprognostic (2.29e-1)" "unprognostic (3.93e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (7.27e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (1.62e-1)" "unprognostic (3.19e-2)" "unprognostic (1.85e-1)" "unprognostic (4.35e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.86e-5)" 0.0 0.0 0.1 1.0 0.1 0.1 2.2 0.1 0.1 3.8 0.0 8.0 7.4 0.3 1.2 14.5 1.6 2.1 1.1 0.0 0.0 2.5 0.1 0.1 0.0 0.0 0.7 0.0 1.5 0.0 0.0 4.3 0.1 1.8 8.2 0.1 4.7 1.1 0.7 25.9 7.4 0.2 0.0 0.0 3.9 0.6 0.0 2.3 3.6 0.1 3.6 4.3 9.8 0.2 13.3 0.2 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 6.5 3.6 0.0 0.0 0.0 0.1 18.1 0.0 9.8 0.1 0.0 2.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 19.7 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.6 4.1 0.0 0.0 0.0 0.0 9.1 19.2 0.2 0.0 2.9 0.6 0.0 3.3 4.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.8 32.5 6.6 43.3 0.0 1.5 3.0 3.1 5.7 6.5 7.3 0.0 11.2 0.1 9.0 0.0 6.1 6.3 8.8 0.8 0.3 1.2 0.0 0.2 3.5 11.9 0.4 9.2 8.1 0.0 0.0 0.4 0.0 0.6 0.0 0.1 5.4 6.1 0.0 1.5 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 17.4 0.0 0.1 9.1 12.6 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.6 31.9 41.1 18.7 0.1 0.0 8.8 25.4 FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.3;skin 1: 67.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 77.8;Basal squamous epithelial cells: 39.3;Distal enterocytes: 46.5;Squamous epithelial cells: 55.3;Suprabasal keratinocytes: 68.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA023369: AB_1848415, HPA023940: AB_1848416" "unprognostic (2.12e-2)" "unprognostic (5.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-3)" "unprognostic (2.04e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.58e-6)" "unprognostic (9.68e-2)" "unprognostic (5.13e-2)" "unprognostic (3.74e-2)" 2.3 2.2 0.8 2.9 0.8 1.4 2.8 0.8 1.2 10.8 2.1 8.2 10.8 2.5 0.9 51.3 1.6 6.4 17.2 0.8 1.9 7.1 21.7 3.2 3.0 1.6 1.4 1.4 9.5 6.4 4.3 0.7 2.7 3.5 5.3 0.2 10.9 2.2 6.9 67.3 11.3 1.5 0.9 2.0 9.8 1.0 1.4 3.7 5.6 0.8 5.7 2.5 17.0 0.7 24.7 22.4 0.2 0.0 0.7 2.0 35.9 25.2 11.0 21.0 15.7 28.7 8.8 16.1 15.1 16.7 17.1 28.6 3.6 21.1 9.6 13.2 8.1 0.4 11.2 15.9 15.3 2.9 7.9 2.8 38.9 13.6 22.3 7.9 7.6 2.5 7.7 0.5 6.0 15.0 0.7 6.0 11.0 34.1 0.1 0.1 0.0 7.8 10.1 6.2 11.2 0.0 8.7 5.3 1.5 29.1 9.2 3.6 14.2 12.9 21.6 6.1 29.8 2.2 4.0 4.1 10.1 0.1 8.6 1.1 0.0 0.0 0.7 0.0 0.3 0.3 0.4 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.8 0.8 0.8 1.2 0.8 1.9 1.6 1.4 2.7 0.9 1.4 0.7 0.6 3.2 2.2 0.0 2.5 77.8 12.2 9.9 39.3 0.2 7.1 2.9 5.1 11.5 6.3 7.3 0.0 0.4 0.7 46.5 0.0 15.8 0.1 2.4 1.0 1.9 7.1 2.7 0.1 10.0 9.7 2.6 17.3 5.0 8.9 3.5 1.1 20.9 1.2 0.0 0.1 17.7 8.2 0.3 7.8 1.9 0.0 1.0 5.4 0.0 1.0 0.2 3.1 0.5 0.0 24.3 22.8 0.0 3.0 13.2 15.3 4.4 2.5 0.4 0.0 1.3 2.0 0.1 1.0 55.3 68.5 1.9 2.6 0.0 17.1 9.1 FANCE "FACE, FAE" ENSG00000112039 "FA complementation group E" Q9HB96 6 35452338-35467102 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 22.1;Extravillous trophoblasts: 104.8;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB014893 Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB014893: " "unprognostic (2.66e-1)" "unprognostic (8.01e-3)" "unprognostic (7.73e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.80e-3)" "prognostic unfavorable (2.08e-9)" "unprognostic (8.90e-2)" "unprognostic (5.70e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.14e-2)" 4.6 1.5 2.6 3.2 2.5 5.8 5.0 2.8 3.1 7.1 2.0 3.1 2.1 3.7 3.4 8.6 4.8 1.5 3.3 2.3 2.9 2.1 1.3 4.1 4.5 2.7 2.6 7.8 3.5 4.0 3.1 9.3 2.6 3.8 3.0 1.8 4.3 2.7 11.0 13.8 3.5 3.1 2.4 3.8 3.4 8.7 2.7 2.6 3.0 3.1 5.7 4.0 7.7 2.7 9.9 4.2 12.8 27.6 9.2 15.9 34.6 11.4 9.6 14.8 12.1 11.1 5.3 33.0 7.5 6.7 11.2 7.2 13.7 9.8 13.9 11.0 11.9 23.8 11.7 6.8 4.8 12.6 8.2 10.1 28.6 17.7 27.7 3.9 8.7 12.6 21.3 11.6 12.2 11.4 5.8 16.6 4.7 10.6 7.0 18.8 12.3 12.1 3.1 10.0 12.1 11.4 6.4 9.1 10.0 11.9 8.8 43.7 5.6 16.7 14.5 10.9 18.1 7.4 29.3 11.6 3.9 24.3 16.8 0.0 0.2 0.2 0.4 0.1 0.7 0.1 0.6 0.9 0.1 0.5 0.3 0.3 0.0 0.5 0.1 0.4 0.3 0.2 2.6 2.5 2.8 3.1 2.3 2.9 2.7 2.6 2.6 2.4 2.7 2.7 7.0 6.4 0.0 1.0 2.4 8.8 4.1 4.7 1.8 1.1 2.0 2.8 2.7 0.0 1.6 0.0 0.0 22.1 2.0 1.6 0.0 1.7 0.3 1.9 2.4 3.7 1.2 2.5 0.4 0.8 104.8 2.8 1.1 3.4 0.0 5.2 1.4 0.7 6.0 0.0 0.9 3.6 0.0 0.8 1.3 0.6 1.5 1.4 1.8 2.8 0.5 1.9 1.0 0.5 1.0 1.1 0.4 0.7 3.1 5.8 1.1 0.3 0.1 2.0 0.0 4.0 3.4 8.2 13.2 4.6 7.1 46.7 2.2 3.4 4.4 3.5 FCER1A FCE1A ENSG00000179639 "Fc fragment of IgE receptor Ia" P12319 1 159289714-159308224 "FDA approved drug targets, Predicted membrane proteins" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.6" "Cell type enriched" "Detected in many" 7 "Langerhans cells: 1962.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 21557.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 21557.7" "Cell line enriched" "Detected in some" 99 "HEL: 447.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB022102, HPA036051, CAB055526" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "CAB022102: , CAB055526: , HPA036051: AB_2674919" "unprognostic (1.78e-2)" "unprognostic (2.26e-2)" "unprognostic (7.32e-2)" "unprognostic (7.51e-2)" "unprognostic (1.32e-2)" "unprognostic (1.44e-3)" "unprognostic (7.19e-2)" "unprognostic (1.97e-3)" "unprognostic (2.44e-1)" "unprognostic (7.20e-2)" "unprognostic (8.54e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.20e-4)" "unprognostic (1.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.70e-1)" "unprognostic (3.39e-2)" 3.9 1.7 0.4 5.7 0.4 14.2 17.3 0.5 0.8 10.6 0.5 7.0 7.1 7.1 5.4 23.0 2.9 14.9 3.2 0.4 0.6 4.7 4.4 14.5 2.5 0.6 0.5 0.7 1.2 2.6 0.8 0.2 0.7 5.9 10.7 0.1 4.0 9.1 2.8 33.6 8.8 7.4 0.4 8.0 3.5 2.3 0.6 4.8 1.2 3.9 10.9 11.9 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 447.9 0.0 0.0 0.0 0.5 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21557.7 14.4 36.4 0.4 4.1 4.4 2.8 4.4 1.5 2645.6 3.1 2.3 3.4 17.2 14.6 11.0 361.0 2.8 132.1 0.4 0.4 0.5 0.8 0.4 0.6 0.6 0.5 0.7 0.4 0.6 0.5 1.6 6.4 33.1 0.3 5.5 37.7 0.1 0.0 0.6 0.0 0.6 1.8 0.6 0.0 1.8 0.0 0.0 0.0 76.8 0.0 0.0 0.0 0.3 0.1 0.0 3.4 0.0 37.8 0.0 0.0 0.1 4.2 0.0 0.1 270.7 0.0 0.0 0.0 6.4 0.0 0.1 0.0 0.0 4.0 1962.9 1.1 0.0 169.1 46.2 0.0 46.8 0.0 3.1 0.0 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.0 1.5 0.0 13.1 0.1 2.6 0.1 0.3 0.2 34.1 0.0 6.8 0.0 0.0 0.0 FGD6 "FLJ11183, ZFYVE24" ENSG00000180263 "FYVE, RhoGEF and PH domain containing 6" Q6ZV73 12 95076749-95217482 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Microglial cells: 90.9;Pancreatic endocrine cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007974 Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA007974: AB_1848520" "unprognostic (1.28e-2)" "unprognostic (2.67e-3)" "unprognostic (6.06e-2)" "unprognostic (5.56e-2)" "unprognostic (1.65e-1)" "unprognostic (4.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.35e-3)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.62e-5)" "prognostic unfavorable (9.83e-4)" "prognostic unfavorable (5.46e-6)" "unprognostic (1.01e-2)" "unprognostic (1.38e-1)" "unprognostic (3.33e-2)" "unprognostic (1.92e-1)" 1.8 3.3 3.3 5.1 5.3 1.5 2.9 0.3 5.2 3.3 4.0 4.5 1.3 3.4 1.2 3.3 1.9 4.9 3.6 3.2 0.4 3.3 3.1 5.2 5.5 2.0 1.7 4.5 3.4 1.2 1.1 4.3 0.3 3.3 4.2 2.2 2.2 4.0 1.6 7.8 3.5 3.5 1.8 3.3 1.8 3.0 2.9 2.5 5.2 1.3 9.7 3.3 3.5 1.6 22.5 20.1 18.2 2.0 1.9 1.8 9.5 3.1 4.4 1.1 1.8 7.7 15.0 23.8 5.1 2.0 1.3 8.9 3.3 18.7 2.6 2.5 2.0 1.1 3.2 3.8 2.5 2.5 0.2 7.5 8.4 2.2 22.1 7.3 11.9 3.2 5.1 0.4 0.6 1.2 2.0 0.5 7.5 2.8 6.9 5.5 3.6 1.9 12.8 7.1 3.0 4.9 9.0 4.6 0.4 9.1 2.1 0.2 16.4 0.7 2.0 0.9 2.4 2.2 5.3 6.7 0.9 1.6 1.4 0.2 1.6 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.9 1.4 0.1 0.0 0.1 0.1 2.0 0.0 0.0 0.6 3.3 5.3 0.3 5.2 3.2 0.4 2.0 1.7 0.3 1.8 2.9 1.6 12.4 16.0 17.0 109.0 3.9 48.6 21.9 18.6 29.0 3.8 11.0 10.5 22.2 10.0 14.0 9.2 4.2 4.5 1.5 26.5 0.0 22.6 1.7 10.9 17.3 22.3 12.5 1.7 23.9 21.9 8.8 7.3 6.6 22.1 1.3 10.6 16.4 5.2 11.7 1.7 22.4 15.5 10.2 16.1 11.8 3.1 12.5 11.0 1.8 90.9 12.6 1.9 1.0 4.0 4.1 78.1 17.0 10.5 3.5 19.3 14.9 5.2 12.0 9.7 0.0 3.5 6.1 4.8 16.0 28.3 24.9 43.8 1.7 4.9 5.5 30.7 FOXN1 "FKHL20, RONU, WHN" ENSG00000109101 "Forkhead box N1" O15353 17 28506243-28538900 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 18.4;lymphoid tissue: 10.7;skin 1: 41.1;vagina: 10.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.0;Prostatic glandular cells: 5.9;Squamous epithelial cells: 15.9;Suprabasal keratinocytes: 12.4;Urothelial cells: 15.4" "Cancer enhanced" "Detected in many" "cervical cancer: 7.0;head and neck cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HaCaT: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.60e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.68e-3)" "unprognostic (5.98e-6)" "prognostic favorable (5.00e-4)" "unprognostic (2.85e-1)" "unprognostic (2.56e-1)" "unprognostic (3.89e-2)" "unprognostic (7.08e-3)" "unprognostic (1.26e-2)" "unprognostic (1.90e-3)" "unprognostic (4.68e-2)" "unprognostic (3.96e-1)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.0 18.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 2.4 0.1 0.1 41.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 10.7 0.1 0.0 5.6 0.8 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.9 1.8 1.2 0.0 0.4 0.6 0.4 0.0 0.3 0.0 0.0 0.8 0.0 2.2 0.0 0.0 0.8 0.3 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.9 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 15.9 12.4 1.1 0.1 0.0 0.4 15.4 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "hTCEpi: 127.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 11.7 10.6 3.0 4.2 2.8 1.0 15.1 3.1 4.3 14.2 5.7 7.0 5.7 13.0 9.5 18.7 23.5 10.6 9.1 2.9 3.0 14.5 4.0 18.6 5.1 3.8 3.1 5.4 11.2 25.3 9.8 15.1 3.8 12.6 7.0 4.6 11.7 10.3 2.0 24.0 4.6 9.3 3.0 4.0 7.4 3.6 3.3 10.0 22.3 5.6 9.9 21.6 10.2 3.2 59.8 11.0 29.6 0.0 7.9 20.6 17.1 31.0 34.1 27.2 17.6 6.2 47.8 0.0 51.4 29.7 9.1 90.3 16.8 65.7 51.0 13.5 18.0 31.4 12.2 8.5 93.4 0.0 0.0 23.0 127.6 29.4 91.5 67.1 58.2 7.0 3.2 27.0 31.5 25.5 29.8 2.7 6.7 4.7 20.6 2.3 12.3 0.0 59.1 39.5 10.0 7.9 44.8 22.8 59.9 15.8 0.0 11.6 4.1 6.1 32.0 24.9 32.7 6.4 3.7 13.3 18.0 0.0 40.4 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.8 0.4 0.3 0.5 0.9 0.4 0.0 4.0 0.0 0.1 0.4 0.2 3.0 2.8 3.1 4.3 2.9 3.0 3.8 3.1 3.8 3.0 3.3 3.2 38.3 25.6 22.5 10.1 2.8 46.9 15.9 51.1 42.7 4.1 16.1 12.7 4.8 8.6 35.4 12.9 2.1 22.7 2.1 4.9 0.0 11.7 9.6 51.0 5.8 42.0 5.3 6.7 19.9 8.2 7.1 7.0 14.8 73.6 0.0 11.2 13.9 3.7 2.4 6.7 7.3 7.4 26.4 1.0 5.1 2.9 1.2 1.3 14.2 16.9 0.7 11.8 1.0 8.5 3.6 9.5 3.2 1.5 8.6 13.4 2.8 7.1 53.8 4.8 0.0 1.6 7.7 7.0 0.8 41.9 44.6 14.6 3.0 1.7 5.6 23.2 GJB3 "CX31, DFNA2, EKV" ENSG00000188910 "Gap junction protein beta 3" O75712 1 34781214-34786369 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 77.8;skin 1: 145.0" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 138.4;Basal prostatic cells: 71.9;Basal respiratory cells: 43.6;Pancreatic endocrine cells: 119.8;Prostatic glandular cells: 63.4;Squamous epithelial cells: 91.9;Suprabasal keratinocytes: 170.6;Urothelial cells: 171.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 58.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 88.8;CAPAN-2: 121.7;HaCaT: 99.4;HBEC3-KT: 84.9;hTCEpi: 136.8;OE19: 54.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA074472 Supported "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cell Junctions" "HPA074472: AB_2686694" "unprognostic (1.34e-3)" "unprognostic (2.30e-1)" "unprognostic (2.84e-2)" "unprognostic (5.22e-3)" "unprognostic (3.82e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-4)" "prognostic unfavorable (4.56e-4)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.50e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-2)" "unprognostic (2.46e-2)" 0.3 0.2 1.3 1.7 0.6 0.0 5.5 1.1 1.0 8.9 0.0 4.2 0.2 0.3 2.8 77.8 1.1 7.0 0.1 0.6 0.0 0.5 1.5 0.6 0.5 0.2 0.0 0.1 0.3 0.0 0.1 1.4 0.1 4.0 5.0 0.0 8.9 1.7 0.6 145.0 1.3 0.1 0.0 0.0 5.9 0.8 0.1 0.8 0.2 0.0 12.9 11.9 26.4 0.2 88.8 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 121.7 0.0 11.6 0.1 0.1 99.4 0.0 84.9 0.0 0.1 0.0 0.3 5.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 35.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.4 54.2 22.3 0.0 0.0 0.0 40.8 33.0 0.0 0.0 13.1 0.9 0.0 0.1 1.0 0.1 0.0 0.1 5.7 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 1.1 1.0 0.6 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 3.2 0.0 0.0 0.0 138.4 71.9 43.6 16.5 0.0 2.0 1.3 0.4 1.5 15.5 5.5 0.0 0.3 0.0 18.3 0.0 14.6 0.0 4.1 0.4 1.7 1.8 0.0 0.2 7.3 0.2 1.7 3.1 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 6.1 0.0 12.5 0.0 0.0 0.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 119.8 8.1 0.0 0.0 63.4 0.5 0.0 10.1 0.0 0.0 0.0 2.1 0.1 0.3 91.9 170.6 0.1 0.5 0.0 19.1 171.0 GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 79768028-80226181 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 220.0;Oligodendrocytes: 410.7;Suprabasal keratinocytes: 214.2;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "NK-cell: 12.8" "Lineage enriched" "Detected in many" 6 "NK-cells: 12.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022449, HPA042141" Approved Supported Nucleoplasm,Nucleoli,Centrosome NA NA 1600000 "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "Nucleoplasm, Nucleoli" "CAB022449: , HPA042141: AB_2677870" "unprognostic (2.29e-1)" "unprognostic (2.83e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.92e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (9.78e-2)" "unprognostic (1.26e-1)" "unprognostic (4.48e-1)" "unprognostic (9.41e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.12e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" 47.5 26.2 8.9 2.6 18.8 0.4 34.9 14.9 17.7 18.5 4.4 25.4 4.7 14.8 0.7 19.7 10.9 3.2 9.4 10.8 13.3 36.6 15.2 15.2 2.0 18.8 15.0 17.1 4.5 1.3 10.9 13.6 18.4 8.8 2.6 1.5 10.4 3.0 6.2 47.9 9.9 4.1 15.5 5.9 17.7 13.0 14.2 1.3 14.2 2.9 1.5 24.7 19.9 36.6 2.2 18.6 10.5 0.0 14.5 7.9 9.1 14.3 7.2 5.5 8.7 0.0 3.4 0.0 4.5 9.3 5.1 2.6 7.0 9.5 5.4 0.0 11.9 10.4 12.9 1.2 14.8 1.8 0.0 12.0 19.9 4.1 9.5 4.4 3.5 0.0 0.0 0.1 7.7 0.6 0.0 0.1 6.1 0.2 11.0 8.6 5.2 7.8 15.7 7.0 12.5 9.2 13.5 0.0 10.3 5.4 2.0 0.3 13.0 21.8 15.6 5.1 4.4 0.0 0.0 0.2 6.1 1.2 10.2 1.3 0.4 0.4 0.1 0.4 0.0 0.0 0.1 0.1 1.9 0.1 1.1 0.5 0.3 12.8 1.0 0.2 0.1 0.4 8.9 18.8 14.9 17.7 10.8 13.3 18.8 15.0 18.4 15.5 14.2 36.6 121.1 19.2 13.8 11.4 0.9 220.0 20.6 81.6 35.3 3.9 7.0 7.7 6.7 21.5 42.3 29.5 0.0 83.6 1.3 11.1 88.0 7.2 1.7 23.2 58.5 31.5 19.9 4.2 71.4 3.8 84.6 35.9 4.6 40.3 30.3 43.9 17.5 20.0 10.0 26.9 77.4 7.8 36.7 1.0 28.6 7.0 33.5 3.9 103.2 4.7 2.9 49.1 0.0 53.3 410.7 9.4 6.3 74.4 1.2 17.4 0.9 18.4 36.8 5.0 111.7 10.6 70.8 9.7 45.7 31.9 214.2 183.5 2.9 2.9 10.7 19.2 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 H2BC8 "H2B.1A, H2B/a, H2BFA, HIST1H2BG" ENSG00000273802 "H2B clustered histone 8" P62807 6 26215159-26216692 "Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.9" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 7.3;Extravillous trophoblasts: 7.4;Hofbauer cells: 22.5;Syncytiotrophoblasts: 24.1" "Cancer enhanced" "Detected in all" "prostate cancer: 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 9.6;SiHa: 10.5;T-47d: 21.2;U-266/70: 19.6" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (4.55e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (4.19e-2)" "unprognostic (1.63e-2)" "unprognostic (8.54e-2)" "unprognostic (6.69e-2)" "unprognostic (1.55e-1)" "unprognostic (2.36e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (1.70e-8)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.97e-2)" 3.1 0.9 1.5 1.2 1.4 6.7 13.2 8.0 1.8 23.9 4.8 5.9 1.1 0.9 2.0 9.1 4.3 0.9 3.3 1.5 1.9 4.3 3.1 7.5 1.6 1.4 2.2 5.7 1.1 0.1 2.9 1.1 3.6 19.7 2.0 1.6 6.9 0.5 0.1 13.2 3.2 0.4 2.8 7.1 3.7 1.8 1.9 4.1 2.6 0.0 1.4 1.6 18.4 4.6 3.0 0.1 1.4 0.0 4.4 0.2 0.4 3.7 0.3 2.3 0.9 0.4 2.6 0.0 3.7 0.3 1.0 3.2 1.3 1.2 1.3 2.6 1.6 0.8 1.5 1.4 0.7 0.3 2.4 1.7 0.6 0.7 0.1 0.1 0.5 0.1 9.6 0.2 0.0 2.2 2.8 2.1 1.5 7.1 1.9 1.8 0.8 5.4 1.3 0.7 8.5 1.3 10.5 3.8 1.2 3.7 21.2 0.9 0.3 0.0 1.2 0.3 0.5 19.6 0.1 0.0 0.3 1.3 0.7 18.1 1.3 3.2 2.0 0.9 6.4 4.4 3.2 4.0 5.1 5.3 1.5 1.3 5.8 1.4 1.8 16.0 3.0 2.2 1.5 1.4 8.0 1.8 1.5 1.9 1.4 2.2 3.6 2.8 1.9 4.6 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 7.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.1 0.2 0.0 0.0 0.0 HLA-DQB2 HLA-DXB ENSG00000232629 "Major histocompatibility complex, class II, DQ beta 2" P05538 6 32756098-32763532 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 52.4" "Cell type enriched" "Detected in some" 33 "Langerhans cells: 1010.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073187 Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 31: Skin - Epidermis development" "Cluster 41: Macrophages - Immune response" "HPA073187: " "prognostic favorable (5.55e-4)" "unprognostic (3.75e-3)" "unprognostic (2.16e-1)" "unprognostic (2.50e-2)" "unprognostic (2.10e-1)" "unprognostic (6.60e-2)" "unprognostic (8.15e-2)" "unprognostic (3.73e-3)" "unprognostic (6.48e-2)" "unprognostic (1.25e-1)" "unprognostic (3.74e-1)" "unprognostic (1.94e-1)" "unprognostic (6.66e-2)" "unprognostic (1.23e-1)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (6.92e-2)" 4.6 1.9 0.0 0.0 0.0 0.1 3.8 0.0 0.0 3.3 0.2 1.8 0.3 0.9 0.1 7.3 1.4 0.5 1.4 0.0 0.0 2.3 0.6 14.6 0.7 0.1 0.0 0.4 0.6 0.0 1.9 0.0 0.0 1.5 1.0 0.0 2.5 0.0 0.8 52.4 6.5 0.0 0.0 12.8 1.3 0.6 0.0 0.2 2.4 0.0 0.4 1.4 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.1 3.2 13.0 0.0 5.9 28.4 0.0 0.1 0.0 0.0 0.4 1.7 0.4 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.2 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 2.5 0.1 0.0 0.0 2.4 0.0 0.1 0.0 0.0 6.2 1010.0 0.5 0.9 30.5 26.6 1.0 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.6 0.2 0.6 0.1 27.6 0.1 2.7 0.0 0.0 0.4 HOXA9 "HOX1, HOX1G" ENSG00000078399 "Homeobox A9" P31269 7 27162438-27175180 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4;skin 1: 25.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Endometrial stromal cells: 31.1;Enteroendocrine cells: 39.4;Proximal tubular cells: 75.1;Suprabasal keratinocytes: 27.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 6.7;myeloid DC: 5.6;NK-cell: 11.5" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;granulocytes: 6.7;NK-cells: 11.5" "Cell line enhanced" "Detected in many" "HEK 293: 124.4;PC-3: 43.9;RPTEC TERT1: 42.0;SCLC-21H: 113.4;U-937: 42.3" "Not detected" "Not detected" "HPA061982, HPA076200" Uncertain Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA061982: AB_2684651, HPA076200: " "unprognostic (4.72e-1)" "unprognostic (1.23e-2)" "unprognostic (2.86e-1)" "unprognostic (5.24e-3)" "unprognostic (2.36e-1)" "unprognostic (2.02e-1)" "unprognostic (8.35e-2)" "unprognostic (8.44e-3)" "unprognostic (5.50e-2)" "unprognostic (5.71e-2)" "unprognostic (9.87e-3)" "unprognostic (4.42e-2)" "unprognostic (2.80e-3)" "unprognostic (6.45e-2)" "unprognostic (7.58e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" 4.7 5.9 0.0 2.8 0.0 2.5 6.9 0.0 0.2 12.7 0.0 22.0 0.0 17.0 5.6 1.0 19.6 0.0 0.0 0.0 0.0 28.4 0.0 0.4 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.8 0.1 14.1 3.9 0.0 0.0 4.5 16.1 25.7 14.8 1.9 0.2 0.9 0.2 0.0 0.0 1.9 0.1 0.0 0.0 16.8 13.8 0.2 37.7 0.0 0.0 18.4 6.0 4.4 0.0 14.6 11.7 1.2 1.2 2.4 1.4 0.3 1.4 7.9 0.0 34.7 23.5 0.0 1.2 0.0 124.4 0.3 1.1 0.0 0.6 0.0 0.5 6.0 0.0 0.0 0.0 0.0 30.6 0.0 0.0 0.0 1.2 0.0 0.0 1.2 0.0 0.0 43.9 8.1 0.0 0.0 42.0 0.7 113.4 0.0 15.6 0.0 0.3 0.6 0.0 31.3 1.4 0.0 11.4 14.0 0.2 0.0 0.0 0.0 0.0 42.3 0.0 6.7 0.8 0.0 1.3 0.2 0.2 0.1 0.0 0.1 5.6 0.9 0.2 0.0 0.8 11.5 0.3 1.8 0.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 6.2 0.0 0.0 0.0 2.0 25.1 14.9 0.0 3.4 0.0 12.2 14.7 0.5 0.0 0.0 18.4 0.0 0.2 2.9 10.5 54.8 0.0 0.0 1.0 31.1 4.3 39.4 16.6 0.0 0.0 0.3 4.8 0.0 0.6 0.0 0.0 0.7 0.0 0.3 0.0 0.0 21.7 0.0 3.4 4.2 0.0 0.0 1.9 5.4 0.0 0.8 0.0 2.1 0.0 0.0 0.0 20.2 0.0 0.9 19.4 13.3 75.1 0.0 0.0 0.0 3.0 4.6 0.0 1.0 2.6 27.6 0.3 2.2 0.3 21.4 14.2 HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 5.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Distal tubular cells: 1.9;Melanocytes: 3.6;Proximal enterocytes: 3.7;Spermatocytes: 3.5;Suprabasal keratinocytes: 3.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 34.7;BJ hTERT+: 17.5;HaCaT: 15.4;HeLa: 12.4;T-47d: 27.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 1.3" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 1.8 5.0 1.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 9.3 1.1 0.0 34.7 3.2 4.9 0.0 5.1 17.5 7.4 5.3 0.3 1.3 0.0 0.3 4.8 0.0 15.4 6.6 0.0 3.3 1.0 0.1 0.2 12.4 0.0 0.0 0.1 0.1 0.9 1.4 0.0 0.4 0.0 0.0 0.3 1.5 0.0 4.8 2.2 0.0 0.1 0.0 10.1 0.1 0.0 0.6 0.0 0.7 1.2 0.0 0.2 3.2 7.8 3.1 0.3 27.4 0.0 0.0 0.0 5.8 0.4 0.3 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.7 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.9 0.0 0.0 0.0 1.0 1.0 3.5 0.9 0.0 3.8 0.0 0.1 0.0 0.2 0.0 HS3ST6 HS3ST5 ENSG00000162040 "Heparan sulfate-glucosamine 3-sulfotransferase 6" Q96QI5 16 1911475-1918415 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 75.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 10.7;Horizontal cells: 21.9;Suprabasal keratinocytes: 9.1;Urothelial cells: 24.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.72e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-1)" "unprognostic (4.99e-3)" "unprognostic (2.10e-2)" "unprognostic (6.55e-3)" "unprognostic (2.42e-1)" "unprognostic (3.61e-1)" "unprognostic (2.26e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.5 0.0 0.0 0.0 14.4 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 1.4 0.0 0.0 1.9 0.0 0.3 75.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 4.1 10.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 3.4 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.7 1.8 0.0 0.2 0.0 6.3 0.0 0.0 4.5 10.7 0.5 0.1 0.0 0.0 0.1 0.0 0.4 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 21.9 0.1 0.9 4.1 0.0 1.5 1.4 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 0.0 2.7 0.2 0.2 5.0 0.2 0.0 0.0 0.3 0.0 0.0 4.5 9.1 0.1 0.1 0.0 1.7 24.9 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" NA NA 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 6.7 10.1 3.4 2.8 3.6 3.5 6.1 3.7 4.2 8.1 5.9 8.6 3.3 7.4 9.7 9.8 6.5 2.9 11.7 3.4 3.7 5.9 11.4 5.9 3.4 3.8 3.7 5.4 12.3 9.5 4.7 2.7 3.9 9.1 3.8 10.3 7.8 4.2 28.8 36.4 6.8 3.7 3.6 6.3 8.2 25.8 3.6 2.4 6.7 9.7 4.1 8.9 7.9 3.8 12.1 22.9 6.2 15.1 10.5 5.8 8.5 10.4 13.3 6.1 5.2 19.4 9.5 12.5 16.4 14.3 7.2 16.3 14.6 10.0 3.9 14.7 8.8 5.1 13.7 25.9 11.5 14.9 6.5 5.4 6.6 9.1 14.0 7.8 8.6 3.3 10.0 8.1 5.4 18.0 6.6 8.8 10.2 10.4 5.2 10.2 10.8 9.0 10.9 19.3 2.2 5.6 14.3 6.4 6.7 6.8 12.6 6.3 15.3 4.4 8.2 5.0 10.4 11.2 12.2 14.5 6.9 10.9 4.4 0.3 3.5 1.4 2.0 4.2 2.2 2.9 2.6 2.9 4.6 2.1 1.9 2.0 0.0 3.7 5.9 1.3 3.9 2.3 3.4 3.6 3.7 4.2 3.4 3.7 3.8 3.7 3.9 3.6 3.6 3.8 12.9 9.6 14.1 20.9 11.1 5.2 6.1 10.5 5.2 15.0 8.7 4.3 45.7 7.2 10.6 7.3 47.9 11.2 10.0 14.0 1.9 14.0 46.4 14.9 19.3 10.8 10.8 19.6 43.3 20.2 5.7 9.1 22.4 16.5 1.3 9.9 11.7 24.1 11.9 6.7 42.6 12.7 18.3 16.6 5.4 12.0 6.5 12.5 8.8 23.4 7.8 7.8 4.1 20.6 24.0 16.5 5.7 10.1 24.2 12.2 9.0 10.7 23.3 26.9 6.6 7.6 13.2 51.5 11.0 19.6 16.3 3.8 8.5 9.8 9.8 9.6 IER2 ETR101 ENSG00000160888 "Immediate early response 2" Q9BTL4 19 13150411-13154911 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 255.5;U-266/84: 338.3" "Low region specificity" "Detected in all" "HPA055387, HPA060574" Enhanced Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055387: AB_2682802, HPA060574: AB_2684324" "unprognostic (3.09e-2)" "unprognostic (1.78e-1)" "unprognostic (1.99e-1)" "unprognostic (4.86e-2)" "unprognostic (3.86e-2)" "unprognostic (2.47e-2)" "unprognostic (2.10e-1)" "unprognostic (3.31e-1)" "unprognostic (2.35e-2)" "unprognostic (7.05e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (5.69e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" "unprognostic (2.86e-1)" "unprognostic (1.01e-1)" 193.3 74.8 26.8 44.2 20.3 239.8 103.8 50.0 28.5 53.8 20.7 115.7 39.6 65.1 7.3 128.6 298.3 36.8 90.7 20.0 23.3 117.8 118.5 136.4 47.3 30.0 27.1 107.5 119.3 31.0 87.8 33.9 30.3 83.8 29.9 16.7 104.8 27.9 26.4 276.3 78.3 45.4 26.4 95.4 139.7 13.7 28.9 45.2 107.7 49.5 20.8 90.7 78.4 25.7 62.4 36.3 28.2 43.0 18.3 24.5 62.2 47.4 25.6 32.0 18.8 31.4 36.9 36.7 46.7 34.5 53.8 41.4 13.1 27.4 15.9 22.2 24.6 48.2 67.9 26.5 22.4 61.2 51.9 12.7 66.3 34.5 21.4 38.9 37.9 37.4 123.6 48.1 12.5 102.4 37.1 255.5 53.5 66.9 155.8 71.8 28.4 45.0 29.5 36.2 34.7 49.7 53.0 160.0 114.5 22.1 19.1 36.6 68.8 67.0 46.2 56.1 138.6 139.9 338.3 37.9 36.3 120.4 53.0 363.9 167.4 273.7 249.7 191.3 214.5 139.9 175.1 202.5 100.5 155.3 114.7 146.8 833.3 215.0 183.7 45.1 178.2 275.5 26.8 20.3 50.0 28.5 20.0 23.3 30.0 27.1 30.3 26.4 28.9 25.7 1678.3 176.3 492.4 31.3 636.9 319.0 1201.7 587.9 659.0 82.2 977.1 1651.1 61.3 571.9 330.0 95.6 35.5 539.9 974.9 807.5 52.8 873.6 14.0 714.9 1302.8 718.1 977.5 75.6 6.7 380.3 541.6 721.1 1071.4 1261.4 489.2 279.8 427.3 83.5 593.9 15.2 7.5 973.4 553.4 316.8 366.4 11.9 137.9 714.3 236.5 48.7 144.7 453.1 185.3 7.5 6.7 494.4 691.5 38.7 484.3 779.5 680.9 44.5 221.7 141.9 644.2 591.4 730.3 6.6 10.1 720.1 441.6 915.6 671.4 313.4 652.7 418.5 IFFO2 ENSG00000169991 "Intermediate filament family orphan 2" Q5TF58 1 18904280-18956676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 43.0;skin 1: 169.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.0;Basal prostatic cells: 83.0;Suprabasal keratinocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "basophil: 12.6" "Lineage enriched" "Detected in single" 18 "granulocytes: 12.6" "Cell line enhanced" "Detected in many" "HDLM-2: 139.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015987, HPA064603" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Plasma membrane" "HPA015987: AB_2121678, HPA064603: AB_2685296" "unprognostic (1.43e-1)" "unprognostic (1.06e-2)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (4.34e-2)" "unprognostic (2.27e-3)" "unprognostic (3.24e-3)" "unprognostic (7.42e-2)" "unprognostic (3.24e-2)" "unprognostic (5.24e-3)" "unprognostic (2.72e-1)" "unprognostic (4.71e-1)" "unprognostic (1.36e-1)" 5.3 9.2 7.4 8.2 6.6 10.4 12.6 19.6 10.6 12.3 0.6 9.0 2.0 7.4 2.4 43.0 5.2 7.0 4.2 6.4 7.9 6.8 5.8 7.5 8.6 11.2 9.3 3.3 19.1 10.7 6.5 7.2 9.7 9.4 2.8 4.3 14.4 9.1 7.9 169.9 3.9 7.1 6.8 6.3 4.4 1.8 9.6 6.2 6.4 4.2 14.0 8.5 21.6 8.8 23.3 37.2 9.9 27.4 6.2 4.9 16.0 17.2 11.4 9.2 6.4 51.5 26.6 0.3 21.6 13.1 10.6 57.6 7.6 36.6 7.4 139.3 6.7 0.4 7.1 20.4 4.5 4.0 21.3 3.2 36.3 12.4 15.7 15.2 19.9 1.2 1.4 4.6 6.1 4.9 3.9 3.7 4.2 23.9 8.8 13.1 6.1 9.8 5.4 14.9 31.6 1.7 13.1 18.2 12.6 10.1 4.9 2.1 54.6 12.4 17.2 7.3 50.5 9.7 11.3 0.8 8.3 5.7 14.8 12.6 0.2 0.0 0.4 0.3 0.5 0.5 0.3 0.4 0.1 0.2 0.3 0.6 0.0 0.2 0.0 0.4 0.3 0.1 7.4 6.6 19.6 10.6 6.4 7.9 11.2 9.3 9.7 6.8 9.6 8.8 4.1 3.2 5.4 5.5 6.0 121.0 83.0 24.1 40.5 6.8 11.5 13.5 6.8 12.8 9.7 1.8 0.0 5.1 20.9 4.9 1.9 17.3 1.3 23.3 5.9 7.7 2.4 3.2 8.5 17.6 5.4 4.7 3.1 10.2 3.8 0.8 4.6 3.4 2.4 25.2 9.6 1.3 2.0 1.6 17.1 4.5 1.2 6.8 14.2 1.0 3.5 4.4 8.2 11.6 8.8 14.6 3.3 3.0 15.5 15.0 0.8 9.3 23.1 1.8 0.0 3.5 7.5 0.8 0.4 32.4 100.3 4.0 13.9 0.4 1.3 44.2 IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.8;skin 1: 31.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.6;Gastric mucus-secreting cells: 58.1;Intestinal goblet cells: 52.1;Paneth cells: 37.7;Proximal enterocytes: 74.4;Undifferentiated cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 38.5;hTCEpi: 16.5;T-47d: 19.4" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019011: AB_1851667" "unprognostic (1.08e-2)" "unprognostic (7.58e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.81e-2)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (6.69e-2)" "unprognostic (6.31e-2)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-2)" 6.1 0.4 0.5 1.4 1.6 0.0 5.9 2.2 1.0 4.5 0.3 16.6 20.8 1.8 2.7 7.5 2.5 6.8 1.2 0.4 0.9 2.8 0.8 8.1 0.4 1.5 0.4 0.6 9.7 4.2 1.6 1.1 2.3 4.8 13.8 0.1 6.3 3.3 0.4 31.0 20.4 1.4 0.4 1.0 16.7 0.2 0.3 2.8 3.2 0.2 1.7 1.7 6.6 0.4 2.6 0.3 0.0 0.1 15.5 38.5 11.3 1.0 1.4 0.3 0.9 2.9 2.3 0.0 0.6 2.7 0.0 7.1 0.0 6.2 0.1 0.1 0.1 0.8 0.2 6.8 0.4 0.0 3.2 2.4 16.5 0.0 0.1 0.0 0.1 2.5 0.1 0.0 0.7 3.1 0.4 11.3 0.1 8.1 0.8 0.0 0.0 0.1 2.8 3.2 0.6 0.2 0.0 6.5 0.0 0.3 19.4 0.3 1.5 0.1 0.0 0.3 0.2 0.2 0.1 0.0 0.4 6.5 0.2 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 2.2 1.0 0.4 0.9 1.5 0.4 2.3 0.4 0.3 0.4 3.4 6.4 1.1 3.3 1.0 14.5 11.9 2.3 14.2 3.0 8.4 8.3 0.9 15.7 2.0 16.5 0.0 4.3 0.8 92.6 7.9 2.7 0.2 1.4 2.0 1.3 33.6 9.0 2.4 4.8 1.8 4.9 58.1 1.3 0.0 1.2 1.8 15.4 2.6 1.7 1.9 52.1 2.0 2.2 3.5 0.4 2.1 1.6 5.4 0.0 1.0 4.7 2.1 2.0 0.6 2.5 37.7 3.4 0.8 6.1 74.4 8.0 1.0 1.0 19.7 1.8 7.2 1.6 2.3 11.8 14.8 0.8 2.8 1.0 40.8 4.6 IL1RL2 "IL1R-rp2, IL1RRP2" ENSG00000115598 "Interleukin 1 receptor like 2" Q9HB29 2 102187006-102240002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 12.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5.6;Excitatory neurons: 9.7;Glandular and luminal cells: 8.4;Langerhans cells: 7.1;Suprabasal keratinocytes: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.1;ASC TERT1: 5.1;HaCaT: 3.8;HSkMC: 4.4;hTCEpi: 2.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (6.70e-2)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" "unprognostic (2.76e-4)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "unprognostic (3.13e-3)" "unprognostic (6.79e-2)" "unprognostic (9.10e-3)" "unprognostic (9.17e-2)" "unprognostic (4.61e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-2)" "unprognostic (8.33e-3)" "unprognostic (3.80e-1)" "unprognostic (1.47e-1)" "unprognostic (7.65e-2)" 1.0 1.5 0.5 0.5 0.6 0.3 2.6 0.1 0.9 1.5 0.0 0.9 0.1 0.4 1.4 5.8 2.3 2.3 0.5 0.7 1.0 4.3 2.9 0.5 0.0 0.8 0.5 0.3 0.5 2.6 0.3 0.3 0.8 0.9 1.1 0.0 2.2 2.3 0.4 12.3 0.3 0.3 0.1 0.1 1.6 0.1 0.9 0.3 2.4 0.7 1.0 1.0 2.5 0.3 8.1 0.0 0.0 0.0 1.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 3.8 0.0 0.6 0.4 0.4 0.0 0.0 1.1 0.0 1.5 0.0 0.0 4.4 2.3 1.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.9 0.7 1.0 0.8 0.5 0.8 0.1 0.9 0.3 1.1 0.0 1.1 0.3 0.0 5.6 2.7 0.7 3.4 0.0 2.1 2.4 0.3 1.5 0.4 1.8 0.0 0.1 0.2 0.5 3.9 0.2 0.3 3.8 2.4 0.9 1.2 0.0 9.7 0.2 0.2 1.4 0.5 8.4 0.0 0.0 0.0 1.3 0.6 0.0 1.1 1.1 0.0 2.8 7.1 0.2 1.5 4.2 0.0 1.9 0.6 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 2.0 0.0 0.4 0.1 0.0 0.0 1.8 1.7 0.0 0.0 5.2 5.5 0.1 0.2 0.6 0.7 1.8 IL20 "IL-20, IL10D, ZCYTO10" ENSG00000162891 "Interleukin 20" Q9NYY1 1 206865623-206869223 "Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.8;skin 1: 1.1" "Cell type enriched" "Detected in some" 4 "Basal keratinocytes: 69.6" "Cancer enhanced" "Detected in some" "breast cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SiHa: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" CAB025802 Uncertain "Secreted to blood" NA NA 109000 "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "CAB025802: " "unprognostic (3.08e-2)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (1.16e-2)" "unprognostic (6.45e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.46e-1)" "unprognostic (1.60e-1)" "unprognostic (3.38e-2)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" 1.8 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.6 6.6 15.1 0.0 0.0 9.4 3.7 0.1 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 2.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.3 0.0 9.9 0.0 0.1 0.0 0.1 7.3 IL20RA "IL-20R1, ZCYTOR7" ENSG00000016402 "Interleukin 20 receptor subunit alpha" Q9UHF4 6 136999971-137045180 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 26.4;skin 1: 37.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 58.6;Endometrial ciliated cells: 110.4;Glandular and luminal cells: 69.8;Muller glia cells: 54.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.5;HaCaT: 6.9;OE19: 10.1;RT4: 11.5;SH-SY5Y: 10.8;T-47d: 10.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB024990, HPA042281" Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Cytosol "CAB024990: , HPA042281: AB_10806235" "unprognostic (3.75e-2)" "unprognostic (8.23e-2)" "unprognostic (1.96e-2)" "prognostic favorable (1.43e-6)" "unprognostic (1.57e-2)" "prognostic favorable (2.29e-5)" "unprognostic (9.87e-3)" "unprognostic (1.64e-1)" "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (8.03e-3)" "unprognostic (2.18e-1)" "unprognostic (1.85e-6)" "unprognostic (9.38e-2)" "unprognostic (1.88e-1)" "unprognostic (3.09e-3)" "unprognostic (1.64e-3)" 0.9 8.8 3.0 0.7 3.5 0.1 26.4 3.9 2.7 17.1 4.9 4.6 3.1 5.9 4.4 7.0 17.3 4.9 2.4 2.4 3.9 0.4 0.4 5.9 0.0 3.7 4.7 4.9 7.9 2.8 1.6 0.2 4.0 8.6 4.6 4.9 9.7 5.5 0.7 37.7 1.3 3.0 4.3 0.0 6.2 2.0 4.2 1.6 1.1 2.4 2.6 6.0 11.9 3.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 9.5 0.0 0.1 1.5 0.1 6.9 1.2 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.3 10.1 1.4 0.0 0.4 0.0 0.0 11.5 0.7 10.8 0.5 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.5 3.9 2.7 2.4 3.9 3.7 4.7 4.0 4.3 4.2 3.5 1.4 3.2 26.1 6.2 0.0 21.9 12.0 12.7 6.2 3.5 58.6 39.5 4.6 37.1 22.3 3.7 0.0 2.7 0.5 12.1 0.0 15.3 0.8 110.4 8.0 1.1 7.3 0.0 0.1 0.7 10.6 5.0 19.9 69.8 2.5 0.1 0.4 0.0 0.5 0.0 1.3 23.1 28.5 0.0 1.6 0.9 8.7 0.8 14.2 0.0 0.0 54.6 0.0 3.0 0.3 13.1 11.7 15.1 0.0 18.7 1.7 1.2 36.0 1.3 0.0 2.3 1.7 0.3 3.8 25.3 18.0 8.2 1.3 6.4 12.3 21.1 IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 110.7;skin 1: 163.3;vagina: 66.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.8;Basal respiratory cells: 115.8;Basal squamous epithelial cells: 60.9;Club cells: 43.0;Early spermatids: 57.0;Late spermatids: 28.8;Squamous epithelial cells: 56.5;Suprabasal keratinocytes: 38.1" "Group enriched" "Detected in many" 5 "cervical cancer: 54.5;head and neck cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 86.0;HBEC3-KT: 140.0;HHSteC: 91.8;hTCEpi: 555.6;hTERT-HME1: 102.6" "Not detected" "Not detected" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Cytosol "HPA063914: AB_2732709" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (7.43e-4)" "unprognostic (2.48e-4)" "unprognostic (2.74e-1)" "unprognostic (3.31e-1)" "unprognostic (7.43e-4)" "unprognostic (4.08e-3)" "unprognostic (7.64e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.57e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.55e-1)" "unprognostic (3.55e-2)" "unprognostic (1.33e-2)" "unprognostic (5.57e-2)" 2.3 0.2 0.1 0.0 0.2 0.0 10.3 0.1 0.6 24.3 0.1 0.6 0.0 0.2 0.0 110.7 0.4 0.0 0.6 0.1 0.1 0.2 5.4 0.5 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.4 0.2 2.2 0.5 0.0 13.6 0.2 1.0 163.3 0.4 0.0 0.1 0.3 0.5 3.7 0.2 2.0 0.5 0.9 9.5 1.3 66.2 0.2 27.2 0.0 0.1 0.4 15.4 64.9 2.6 0.6 1.8 0.3 1.2 2.7 3.4 0.2 14.9 9.7 1.0 86.0 0.0 140.0 0.7 0.4 0.0 0.3 19.5 0.0 91.8 0.2 0.2 11.5 555.6 4.5 102.6 0.7 0.1 0.1 0.3 0.1 0.0 0.0 0.6 0.0 0.4 2.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.0 54.6 0.0 2.8 4.7 0.5 0.9 0.0 0.2 1.8 0.5 0.5 0.1 0.2 0.2 8.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.7 0.0 0.0 0.7 0.0 36.8 1.7 115.8 60.9 0.0 0.3 0.5 0.4 0.0 43.0 0.0 0.0 1.7 0.8 0.8 0.0 0.9 57.0 0.7 0.4 0.9 0.0 0.0 1.0 0.2 1.4 3.9 0.0 0.8 0.0 0.2 0.0 2.2 0.4 0.0 1.2 0.7 10.2 0.3 6.6 28.8 0.3 0.6 3.6 1.0 1.7 0.0 1.0 1.0 0.2 1.0 0.1 0.7 0.4 1.3 0.2 0.3 5.5 0.0 0.0 0.6 3.6 1.7 1.9 56.5 38.1 1.6 0.6 0.2 0.5 5.3 IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.2;lymphoid tissue: 3.8;skin 1: 8.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "GAMG: 71.8;U-87 MG: 73.3" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" NA NA 15300 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "HPA035664: AB_10669672" "unprognostic (8.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.77e-2)" "unprognostic (2.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.10e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 1.4 0.0 0.0 0.0 0.0 73.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 26.5;lymphoid tissue: 43.7;skin 1: 60.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.9;Extravillous trophoblasts: 2.0;Syncytiotrophoblasts: 3.8" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 25.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BEWO: 26.6;GAMG: 11.1;U-87 MG: 19.9" "Not detected" "Not detected" "Secreted to blood" NA NA 107000 "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (3.88e-3)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (4.29e-1)" "unprognostic (8.68e-3)" "unprognostic (9.80e-2)" "unprognostic (2.48e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (5.37e-2)" "unprognostic (3.85e-3)" "unprognostic (4.23e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 3.4 0.0 0.0 0.0 0.0 4.6 0.0 0.1 60.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 43.7 0.0 9.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.1 1.1 0.3 0.0 0.0 11.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.0 0.0 0.0 0.7 IRX3 IRX-1 ENSG00000177508 "Iroquois homeobox 3" P78415 16 54283304-54286787 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 89.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 66.7;Breast glandular cells: 133.8;Breast myoepithelial cells: 84.6;Endometrial ciliated cells: 73.0;Glandular and luminal cells: 88.2;Respiratory ciliated cells: 67.3;Squamous epithelial cells: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 119.4;NB-4: 204.4;RPTEC TERT1: 236.4;T-47d: 122.9;THP-1: 201.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066576 Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA066576: " "unprognostic (4.21e-3)" "unprognostic (4.50e-2)" "unprognostic (2.34e-2)" "unprognostic (1.04e-1)" "unprognostic (3.34e-2)" "unprognostic (2.35e-1)" "unprognostic (1.39e-1)" "unprognostic (1.35e-2)" "unprognostic (1.52e-1)" "unprognostic (9.75e-2)" "unprognostic (2.92e-1)" "unprognostic (1.07e-1)" "unprognostic (3.15e-2)" "unprognostic (5.40e-2)" "unprognostic (2.39e-1)" "unprognostic (8.20e-2)" "unprognostic (1.25e-1)" 8.2 6.8 3.4 0.4 3.0 0.1 75.6 6.3 1.2 29.7 2.7 0.3 0.4 2.2 36.5 33.0 10.9 0.3 63.1 1.2 5.1 42.6 2.2 36.5 2.0 7.5 8.1 0.9 4.0 27.2 7.2 1.9 6.2 23.2 0.0 1.2 43.2 31.3 22.7 89.3 0.6 1.2 6.2 0.1 22.5 0.5 7.5 1.0 9.3 8.8 4.5 4.8 17.5 5.0 1.1 1.1 15.6 15.1 8.4 3.3 1.7 6.6 14.5 13.9 3.4 4.2 6.8 0.0 2.2 10.0 5.5 29.0 12.6 3.6 18.5 14.3 9.8 0.0 22.2 14.6 0.6 16.7 4.1 2.5 59.7 26.5 12.0 9.8 0.0 19.1 0.0 0.0 119.4 7.7 30.9 204.4 1.1 0.0 0.0 23.2 19.2 0.0 236.4 6.2 10.6 1.9 20.4 51.3 2.6 1.7 122.9 201.8 3.4 57.9 6.4 10.6 5.3 0.0 0.0 0.1 38.0 53.7 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.0 6.3 1.2 1.2 5.1 7.5 8.1 6.2 6.2 7.5 5.0 2.6 19.2 66.7 0.0 0.4 25.0 47.4 25.3 45.5 1.3 133.8 84.6 14.1 0.0 43.2 5.5 0.0 0.1 1.3 0.1 1.9 5.2 0.0 73.0 8.1 5.8 0.0 0.0 0.0 0.2 0.1 18.3 2.0 88.2 0.0 5.5 8.2 7.1 0.3 0.0 0.0 0.0 36.7 1.2 2.7 0.0 0.0 9.0 10.6 0.0 0.2 10.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 25.8 0.0 6.5 67.3 1.2 0.0 32.1 6.4 0.4 1.0 72.8 41.3 0.0 1.1 0.1 0.0 34.0 IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 14.0;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 40.3;Breast myoepithelial cells: 55.5;Granulosa cells: 43.8;Muller glia cells: 43.1;Squamous epithelial cells: 33.9" "Cancer enhanced" "Detected in many" "breast cancer: 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.1;T-47d: 36.6;THP-1: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: AB_10962983" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-2)" "unprognostic (1.42e-2)" "unprognostic (3.89e-2)" "unprognostic (5.38e-3)" "prognostic favorable (4.59e-4)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (1.17e-3)" "unprognostic (3.34e-2)" "unprognostic (8.90e-2)" "unprognostic (1.77e-3)" "unprognostic (4.28e-2)" 1.7 0.6 1.3 0.0 1.5 0.0 14.0 4.1 0.4 1.8 0.3 0.2 0.0 0.1 0.0 7.2 0.2 0.1 9.8 0.3 1.9 6.9 0.0 6.4 0.0 3.6 4.1 0.3 0.1 0.3 0.4 0.0 3.1 3.4 0.0 1.3 10.2 0.2 1.4 16.9 0.0 0.0 3.6 0.0 2.6 0.7 4.6 0.3 0.1 1.1 0.0 0.6 5.9 3.5 0.8 0.5 8.6 3.2 3.1 0.6 0.4 3.3 8.2 1.1 0.8 1.9 0.8 0.0 0.7 4.5 0.3 8.4 3.0 3.6 0.6 6.0 4.1 0.9 3.4 0.0 0.1 2.0 3.3 0.8 15.1 5.4 2.3 1.5 0.0 4.8 0.5 0.0 6.2 3.3 9.6 12.3 0.1 1.3 2.4 5.0 4.4 0.5 27.1 0.2 2.9 3.0 1.4 7.3 3.9 0.0 36.6 20.2 0.5 5.9 0.2 4.2 1.3 3.6 2.3 2.9 9.6 3.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 4.1 0.4 0.3 1.9 3.6 4.1 3.1 3.6 4.6 3.5 2.4 9.6 21.9 0.0 0.1 8.3 9.7 6.7 15.9 8.6 40.3 55.5 11.1 0.0 15.4 0.0 0.0 0.2 1.0 0.2 0.0 0.3 1.0 9.6 1.2 1.6 0.0 0.0 0.0 0.6 0.0 5.3 7.7 12.2 0.0 43.8 0.0 0.0 0.2 1.7 0.0 0.8 4.1 0.0 2.7 2.4 0.0 0.6 5.4 0.0 0.0 43.1 0.0 0.0 0.0 2.9 0.3 0.0 0.3 4.8 0.0 1.5 13.0 1.9 0.0 8.3 5.2 0.7 2.8 33.9 8.0 0.0 0.4 0.0 0.5 8.5 IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.8;heart muscle: 9.8;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Collecting duct cells: 5.5;Hofbauer cells: 4.7;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HEK 293: 1.9;RPTEC TERT1: 7.1;SK-MEL-30: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" "HPA018332: AB_1851920" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (4.93e-4)" "unprognostic (2.48e-2)" "unprognostic (6.50e-2)" "unprognostic (3.46e-1)" "prognostic favorable (3.34e-4)" "unprognostic (3.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-2)" "unprognostic (2.83e-2)" "unprognostic (9.63e-3)" "unprognostic (7.12e-3)" "unprognostic (5.48e-2)" "unprognostic (5.23e-3)" 9.8 0.1 0.2 0.0 0.6 0.0 4.8 1.1 0.3 2.3 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.1 9.8 0.0 1.1 2.7 0.0 1.8 0.1 0.5 0.8 0.2 0.1 1.7 0.2 0.1 0.6 0.2 0.0 1.6 1.9 0.0 2.8 8.9 0.3 0.1 0.2 1.3 0.0 0.4 0.6 2.2 0.6 1.3 1.1 0.0 0.5 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.1 0.0 1.1 4.8 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.3 0.0 1.1 0.5 0.8 0.6 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.5 0.0 7.5 0.4 0.6 1.3 0.0 1.2 5.5 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.8 0.0 0.6 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.7 5.1 0.0 0.1 3.6 0.0 0.6 1.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.3 0.1 0.5 0.0 1.0 0.1 0.0 0.0 0.0 0.0 ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 123.0;Gastric mucus-secreting cells: 127.4;Late spermatids: 220.4;Pancreatic endocrine cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 164.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" 16.3 11.4 5.5 17.0 5.0 6.1 14.6 3.8 5.3 18.0 3.7 26.2 29.1 8.5 13.1 18.1 14.0 15.3 15.0 3.8 3.9 16.4 2.2 30.6 20.4 5.6 5.0 13.5 11.3 2.8 7.4 4.3 5.2 13.9 18.4 0.8 18.5 11.2 4.5 58.9 35.1 4.7 4.7 39.8 41.5 15.4 7.0 14.3 54.0 5.1 21.0 12.1 24.0 3.9 73.7 34.0 6.3 0.3 6.2 19.3 40.9 24.8 62.8 30.5 27.4 46.7 55.9 62.6 26.1 17.9 76.1 70.9 28.6 66.7 15.7 36.8 24.0 0.1 102.6 52.0 14.1 11.3 7.9 14.0 59.2 76.7 164.7 66.5 52.1 24.5 25.0 19.7 33.3 35.0 19.0 6.4 6.2 55.8 49.4 29.0 0.1 37.1 107.6 50.9 57.3 2.1 42.8 61.6 60.2 6.9 21.2 5.9 71.8 41.1 20.1 53.1 55.2 13.5 14.3 29.4 32.8 16.6 24.1 0.8 0.0 0.0 0.8 0.0 0.6 0.4 0.4 0.5 0.0 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.7 0.2 5.5 5.0 3.8 5.3 3.8 3.9 5.6 5.0 5.2 4.7 7.0 3.9 12.4 48.1 58.9 0.3 13.5 26.5 10.9 27.9 18.2 1.5 9.3 9.9 2.7 12.8 20.2 31.3 0.0 0.3 10.9 52.9 0.0 28.4 123.0 19.1 9.1 18.2 23.9 6.6 1.1 30.2 6.3 9.2 127.4 43.1 0.0 0.2 12.5 0.4 0.5 0.0 1.6 41.6 10.2 0.6 6.9 220.4 23.3 2.6 12.4 23.4 3.2 0.4 4.1 0.5 0.4 89.7 41.6 13.9 18.7 20.5 45.9 0.2 12.1 1.2 6.6 3.9 3.3 1.6 3.2 14.5 25.4 0.5 13.1 5.8 35.6 20.7 ITPRIPL2 "FLJ22994, LOC162073, MGC126798, MGC126800" ENSG00000205730 "ITPRIP like 2" Q3MIP1 16 19113932-19121629 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 54.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042011 Approved Centrosome NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 36: Stromal cells - Cell proliferation" Centrosome "HPA042011: AB_2677795" "unprognostic (1.07e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (9.64e-2)" "unprognostic (1.97e-1)" "unprognostic (2.20e-1)" "unprognostic (3.76e-2)" "unprognostic (6.72e-3)" "unprognostic (5.60e-2)" "unprognostic (1.90e-2)" "unprognostic (5.26e-3)" "unprognostic (4.24e-2)" "unprognostic (1.53e-1)" "unprognostic (7.23e-2)" "unprognostic (6.37e-2)" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" 16.5 7.4 4.6 9.3 4.6 1.6 8.7 4.4 4.2 10.4 5.4 8.0 6.8 8.3 5.3 11.6 6.4 9.3 6.5 4.1 5.0 5.4 5.7 11.6 4.1 6.4 6.1 9.5 8.7 7.6 2.7 12.1 6.2 9.0 6.6 0.5 5.5 9.3 6.9 21.6 6.1 8.9 6.6 5.9 10.0 2.5 6.2 1.6 5.1 7.3 5.0 11.6 8.0 5.8 17.3 10.1 4.3 13.7 36.0 54.3 23.0 28.0 20.9 8.4 7.8 4.6 31.9 0.0 25.9 23.7 9.6 19.3 6.0 8.9 11.2 0.1 5.9 1.5 23.2 7.8 23.3 0.2 0.2 36.3 24.9 16.4 18.7 15.3 11.3 0.1 2.6 0.2 20.5 12.8 0.1 0.6 4.1 4.0 12.3 0.0 0.6 0.1 12.9 31.5 0.3 5.0 23.2 2.4 14.3 6.9 13.3 3.0 21.8 28.7 10.8 14.3 10.7 0.1 0.1 0.1 16.3 0.6 14.1 0.6 1.2 0.1 0.2 1.5 0.1 0.2 0.1 0.1 0.8 0.1 0.1 0.1 0.4 0.1 1.4 0.3 0.0 0.2 4.6 4.6 4.4 4.2 4.1 5.0 6.4 6.1 6.2 6.6 6.2 5.8 38.0 51.3 37.7 13.1 3.3 12.7 25.0 20.0 26.7 0.5 18.8 12.6 7.1 11.5 31.1 25.8 2.1 16.6 3.6 22.0 1.9 15.4 0.4 18.5 76.6 37.5 14.4 4.0 1.1 31.6 10.5 36.7 25.5 27.9 5.7 12.0 35.7 26.9 22.3 5.0 1.6 19.3 26.4 57.8 23.2 1.7 26.8 28.8 14.2 22.5 40.6 2.0 1.0 6.6 0.2 41.6 12.7 30.1 10.0 36.0 8.3 0.2 23.4 0.4 39.5 54.4 36.4 0.2 1.8 23.1 17.3 14.4 4.9 18.9 18.9 35.9 JAG1 "AGS, AHD, AWS, CD339, HJ1, JAGL1" ENSG00000101384 "Jagged canonical Notch ligand 1" P78504 20 10637684-10673999 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 211.1;Endometrial ciliated cells: 197.4;Smooth muscle cells: 190.1;Squamous epithelial cells: 343.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 219.2;hTERT-HME1: 131.1;U-251 MG: 187.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010343, HPA021555" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 25000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane" "CAB010343: AB_649685, HPA021555: AB_1851969" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (4.15e-2)" "unprognostic (1.21e-1)" "unprognostic (6.42e-2)" "unprognostic (4.21e-2)" "unprognostic (8.94e-3)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (4.10e-6)" "unprognostic (5.48e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.10e-1)" "unprognostic (1.41e-3)" 44.2 10.1 10.3 13.0 9.5 21.8 30.3 8.4 12.0 44.0 8.9 23.7 13.8 27.3 19.5 52.4 27.0 21.6 20.7 12.8 9.8 21.7 6.2 23.9 8.4 12.4 14.2 20.3 22.0 20.9 8.2 67.9 10.0 25.9 23.0 22.1 15.8 26.7 9.8 57.2 13.6 23.6 9.7 23.3 25.1 4.5 12.1 9.3 19.9 22.8 15.6 28.5 50.0 8.5 4.1 20.6 63.1 78.1 11.8 11.3 2.3 2.4 11.9 3.3 1.8 18.5 11.2 0.7 59.0 2.4 17.7 85.8 9.4 219.2 2.7 0.2 4.5 7.0 2.2 87.9 5.8 28.4 0.5 4.6 63.7 10.6 131.1 12.5 21.1 0.3 0.1 8.8 6.0 0.2 0.0 20.2 18.2 68.7 20.3 5.3 3.9 13.1 29.9 25.6 2.8 2.1 6.3 4.4 26.2 49.8 0.3 3.3 80.5 14.2 9.9 11.8 187.9 3.6 0.6 0.9 9.1 10.3 11.3 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 10.3 9.5 8.4 12.0 12.8 9.8 12.4 14.2 10.0 9.7 12.1 8.5 73.0 41.7 15.4 5.9 1.1 104.6 54.9 76.3 211.1 9.7 13.2 29.1 20.6 30.0 34.4 16.5 43.8 16.9 6.8 64.3 1.9 31.6 5.0 197.4 22.2 102.5 5.3 0.0 6.9 30.4 1.0 41.9 76.0 96.4 7.0 2.7 60.0 1.8 4.2 21.9 9.2 12.8 20.3 5.9 33.9 9.6 21.5 9.1 14.2 22.5 2.8 11.9 2.1 24.6 1.3 97.3 18.3 33.8 4.3 24.5 7.8 2.3 30.2 69.1 85.5 46.7 190.1 0.9 3.2 343.9 106.8 2.2 4.3 107.2 39.1 33.7 JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.1;Basal respiratory cells: 30.9;Basal squamous epithelial cells: 27.3;Breast myoepithelial cells: 26.4;Endothelial cells: 34.2;Horizontal cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.6;HBEC3-KT: 21.0;SCLC-21H: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Supported Vesicles,Cytosol NA NA 370000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "CAB025481: , HPA030636: AB_10602607, HPA050567: AB_2681178" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (4.28e-2)" "unprognostic (6.97e-3)" "unprognostic (3.50e-1)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (9.19e-2)" "unprognostic (8.47e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.39e-1)" "unprognostic (2.17e-1)" 7.2 1.0 4.0 1.3 3.6 0.1 9.6 0.9 5.0 4.6 0.5 3.1 1.1 5.3 0.4 8.8 5.3 1.8 12.8 3.5 7.4 4.3 0.9 5.1 0.7 4.6 4.4 1.5 6.8 1.5 17.4 3.0 6.8 8.1 0.2 0.8 7.8 2.8 9.7 19.5 4.0 1.1 2.5 2.0 3.0 3.2 6.5 1.6 4.7 2.8 0.6 5.2 6.8 1.6 16.8 6.7 0.4 1.7 0.0 0.0 20.0 0.2 0.1 0.0 0.0 5.6 20.1 0.0 13.8 0.0 0.1 62.6 4.0 21.0 0.0 2.3 9.7 0.0 20.0 0.0 0.2 0.1 3.9 0.2 9.9 0.0 2.3 0.2 5.1 0.9 4.1 0.0 0.0 7.6 0.0 0.0 2.0 2.1 2.3 5.3 3.9 7.2 0.1 4.4 31.4 1.0 5.6 1.3 0.2 0.3 15.8 2.5 17.2 0.1 1.7 0.0 0.2 0.9 0.1 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.6 0.9 5.0 3.5 7.4 4.6 4.4 6.8 2.5 6.5 1.6 56.1 6.4 3.2 1.0 0.2 23.3 7.6 30.9 27.3 2.7 3.8 26.4 6.7 2.8 7.6 0.0 25.0 2.2 2.2 2.7 0.0 3.9 0.1 16.5 0.9 34.2 0.0 0.0 12.1 2.7 1.0 1.8 2.0 7.4 0.0 1.1 7.9 0.6 0.7 26.9 9.9 3.6 4.1 0.8 2.9 1.0 1.5 1.1 7.2 15.0 1.3 0.6 1.0 0.5 1.1 3.3 2.1 0.7 0.9 4.4 8.2 0.3 11.5 4.8 0.0 3.7 3.7 0.8 13.5 6.0 6.8 1.4 3.4 0.3 2.7 1.5 JMJD7-PLA2G4B ENSG00000168970 "JMJD7-PLA2G4B readthrough" 15 41828095-41848155 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 4.8;Club cells: 2.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "RT4: 2.6" HPA005726 Approved Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA005726: AB_1852017" "unprognostic (9.87e-3)" "unprognostic (5.65e-2)" "unprognostic (1.27e-2)" "unprognostic (6.86e-3)" "unprognostic (1.04e-1)" "unprognostic (1.84e-3)" "unprognostic (1.47e-1)" "unprognostic (7.21e-3)" "unprognostic (4.52e-2)" "unprognostic (4.92e-2)" "unprognostic (1.53e-2)" "unprognostic (1.02e-3)" "unprognostic (1.02e-3)" "unprognostic (3.98e-1)" "unprognostic (1.33e-1)" "unprognostic (2.15e-1)" "unprognostic (4.75e-3)" 1.1 0.3 0.1 0.8 0.0 1.0 0.9 0.3 0.4 1.4 0.5 0.9 0.2 1.1 0.4 1.9 1.1 0.4 0.6 0.1 0.1 0.4 0.3 0.9 0.2 0.1 0.1 1.2 0.5 0.9 0.4 0.1 0.3 0.7 0.2 0.2 1.5 0.4 0.8 2.8 0.8 0.6 0.1 0.6 0.8 0.3 0.3 0.4 0.8 0.5 0.3 1.0 1.4 0.2 0.2 0.0 0.6 2.0 0.5 1.3 0.7 0.4 1.1 0.5 0.8 0.8 0.0 0.2 0.8 0.5 0.0 1.8 0.2 1.2 0.1 0.0 0.2 0.3 0.4 0.2 1.9 0.0 0.9 0.7 0.9 0.2 0.4 0.0 0.2 0.7 0.0 0.3 0.1 0.3 0.2 0.0 0.0 0.4 0.1 0.3 0.0 0.8 0.5 2.6 0.6 0.8 1.8 0.0 0.2 0.0 0.4 2.1 0.3 0.3 0.2 2.0 0.7 0.5 0.2 0.0 1.0 0.2 0.2 0.0 0.3 0.0 1.1 0.4 0.5 0.2 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.4 0.1 0.1 0.1 0.1 0.3 0.1 0.3 0.2 0.2 9.6 4.8 0.0 0.9 0.1 0.2 0.1 2.2 0.6 0.4 0.1 0.6 1.5 2.7 0.0 0.0 0.2 0.1 1.1 0.0 0.6 0.0 0.1 0.3 0.4 2.4 0.0 0.0 0.5 0.1 0.2 1.5 0.4 1.3 0.1 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 0.1 1.0 0.0 0.1 1.1 0.5 0.0 2.3 0.1 1.2 0.0 0.9 0.6 0.0 0.1 0.2 0.0 0.1 2.0 1.0 0.1 1.0 0.1 1.2 0.1 KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 90.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 103.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA077577 Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" 2.0 0.7 2.7 0.2 2.9 5.4 2.9 3.4 5.7 4.6 1.7 2.1 0.4 1.4 0.1 18.0 2.3 0.3 1.6 2.7 2.4 0.7 0.9 1.7 0.3 2.8 2.8 1.8 0.4 0.0 1.3 0.4 3.0 1.4 0.0 0.7 2.5 0.3 2.6 90.0 1.2 0.2 2.7 2.0 1.2 1.1 2.7 0.4 0.6 0.5 1.0 1.7 9.5 3.4 0.3 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 1.0 0.4 0.4 0.1 0.2 2.2 0.0 0.0 0.0 0.5 1.1 0.5 0.9 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.6 1.3 0.4 1.0 0.5 0.4 0.6 0.6 0.6 0.9 0.0 0.2 0.6 0.1 6.8 1.5 0.3 0.4 0.7 0.0 0.4 1.1 0.0 0.3 1.1 1.0 0.1 0.9 0.7 0.2 0.5 0.6 0.6 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 2.7 2.9 3.4 5.7 2.7 2.4 2.8 2.8 3.0 2.7 2.7 3.4 1.1 0.0 0.5 0.3 0.8 19.1 0.4 0.7 0.6 2.1 0.7 1.8 0.2 0.0 0.7 0.0 0.0 0.1 1.6 1.0 0.0 0.1 0.7 0.7 0.3 1.2 1.2 0.0 0.9 0.0 0.1 0.4 0.0 1.7 0.0 0.2 0.7 0.3 0.5 0.0 0.9 0.4 0.0 1.3 4.0 1.8 0.6 0.7 3.6 0.0 0.4 0.1 0.0 1.0 1.8 0.1 4.8 0.0 0.0 0.3 0.3 0.1 1.1 1.1 6.6 0.4 0.8 0.1 1.3 16.3 103.7 0.0 0.6 0.1 0.8 1.3 KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367228 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 90.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB003673: AB_425440, HPA044884: AB_2679131" "unprognostic (4.44e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-2)" "unprognostic (4.56e-2)" "unprognostic (5.88e-3)" "unprognostic (7.50e-3)" "unprognostic (1.80e-2)" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-2)" "unprognostic (6.81e-2)" "prognostic favorable (9.53e-6)" "unprognostic (3.32e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-3)" 32.3 22.4 12.8 8.1 19.9 4.8 25.4 19.5 16.7 26.9 12.3 24.6 7.0 22.7 20.8 22.4 18.9 12.6 20.7 12.7 16.4 20.1 36.7 21.5 7.0 20.6 17.7 21.3 15.7 13.1 12.1 8.5 20.0 16.3 7.4 7.0 22.8 11.6 16.7 44.5 15.1 13.3 17.6 8.4 16.4 6.1 16.6 7.1 17.2 8.9 6.8 23.9 23.4 22.4 14.9 6.5 6.7 7.5 52.6 39.0 13.0 48.8 29.7 10.5 13.9 2.7 10.0 15.1 20.3 19.1 17.4 64.6 8.7 27.3 12.8 28.6 14.5 11.6 8.7 3.4 40.1 22.0 7.8 37.4 50.7 16.8 47.9 19.3 10.5 9.9 9.5 21.0 28.1 6.2 23.6 9.7 8.0 3.7 23.5 15.5 19.7 21.9 29.0 9.6 8.5 16.4 23.4 11.3 21.9 8.8 6.1 12.1 24.9 44.0 10.6 14.8 21.3 90.4 44.9 8.7 33.2 13.0 13.4 0.1 5.2 0.5 6.5 8.1 26.6 5.7 13.6 10.2 8.0 4.7 9.3 6.1 1.3 14.2 3.9 3.8 19.1 5.3 12.8 19.9 19.5 16.7 12.7 16.4 20.6 17.7 20.0 17.6 16.6 22.4 53.1 35.3 49.1 21.9 30.1 158.6 131.7 47.0 122.3 37.4 63.4 63.6 27.7 62.9 43.5 38.6 27.1 58.8 15.6 34.6 15.6 50.7 1.0 43.9 53.0 48.1 20.4 17.4 19.1 36.7 70.4 82.0 26.5 64.9 26.0 52.3 51.8 88.3 36.4 40.4 24.2 31.8 42.7 32.2 47.7 6.5 71.1 39.9 56.9 14.0 31.5 56.5 13.4 21.6 57.0 47.4 44.6 70.7 24.5 104.3 43.4 39.6 41.2 41.1 32.9 73.7 48.4 1.3 5.2 89.7 143.1 91.4 37.7 51.1 40.3 94.7 KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.0;Basal prostatic cells: 50.8;Ductal cells: 39.1;Prostatic glandular cells: 66.9;Suprabasal keratinocytes: 183.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 36.1;HaCaT: 16.2;HBEC3-KT: 10.5;hTCEpi: 12.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" 0.3 0.2 0.5 0.3 1.1 3.0 3.3 1.3 0.8 10.0 0.0 0.1 0.1 0.2 2.1 26.1 0.3 0.2 0.2 0.4 0.2 5.9 0.2 0.9 0.3 0.5 0.0 0.2 4.0 4.0 2.7 0.2 0.2 2.6 0.2 1.0 11.6 1.0 0.9 104.1 0.3 0.0 0.0 0.3 0.5 3.7 0.2 1.0 0.7 0.0 1.8 0.2 20.5 0.7 36.1 0.2 0.2 0.4 0.1 0.1 2.8 0.2 0.0 0.0 0.1 3.5 6.5 0.3 2.8 0.0 3.7 16.2 2.2 10.5 0.2 0.8 5.3 0.1 1.1 0.7 0.0 0.3 2.2 0.0 12.9 0.1 2.5 0.4 0.0 0.5 0.6 0.4 0.1 4.7 0.1 0.4 0.8 0.6 1.1 5.6 0.0 0.3 0.3 1.3 4.5 0.7 0.3 7.3 1.0 0.4 6.5 0.1 0.0 0.4 3.6 0.3 0.4 0.7 0.8 0.3 0.2 0.2 0.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.0 0.5 1.1 1.3 0.8 0.4 0.2 0.5 0.0 0.2 0.0 0.2 0.7 0.2 0.0 2.4 0.3 0.0 142.0 50.8 17.5 14.8 0.8 10.3 25.3 0.4 2.8 7.3 1.8 0.0 0.2 0.2 0.2 9.8 39.1 3.0 0.9 0.3 1.7 0.0 2.7 0.3 3.1 0.7 1.4 0.0 2.4 0.0 6.7 0.4 0.0 0.3 1.7 0.4 0.5 6.1 0.0 10.9 12.0 1.8 0.4 14.2 0.0 0.8 0.7 0.0 0.0 0.0 11.8 0.0 0.4 0.0 66.9 0.0 1.4 3.8 2.0 0.0 1.1 2.5 0.6 11.3 25.6 183.3 0.7 1.0 0.0 0.1 22.0 KLF4 "EZF, GKLF" ENSG00000136826 "Kruppel like factor 4" O43474 9 107484852-107490482 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 254.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1054.7;Basal squamous epithelial cells: 832.1;Distal enterocytes: 789.2;Intestinal goblet cells: 710.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.0;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.2;hTCEpi: 84.4;hTERT-HME1: 54.5;OE19: 47.2;U-2197: 111.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002926 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA002926: AB_1852541" "unprognostic (2.06e-1)" "unprognostic (1.42e-2)" "unprognostic (1.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-3)" "unprognostic (3.44e-2)" "unprognostic (6.49e-2)" "unprognostic (3.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "prognostic favorable (3.93e-5)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (8.13e-2)" "unprognostic (8.32e-2)" 73.5 23.9 5.1 21.0 4.7 50.5 63.7 4.0 7.8 53.2 4.6 87.3 28.4 16.0 5.6 102.1 43.0 44.3 31.0 3.7 5.1 6.2 12.4 44.8 5.6 5.0 4.7 29.0 7.0 5.7 4.9 32.4 5.0 16.7 96.0 0.8 27.5 7.6 14.2 254.7 40.5 40.6 4.1 24.1 58.0 17.8 6.0 17.0 25.2 23.2 14.5 43.9 58.9 4.0 13.3 3.9 0.6 0.1 16.6 39.2 5.2 4.4 27.6 6.7 8.1 1.0 18.0 0.0 0.6 6.9 23.7 8.7 6.1 3.9 3.0 0.0 2.2 0.0 7.5 0.3 21.6 0.0 0.0 5.0 84.4 14.0 54.5 1.5 0.6 0.2 0.6 0.0 4.1 7.3 0.0 1.4 4.1 47.2 25.2 0.3 1.6 0.2 2.3 3.7 0.4 0.2 4.0 11.8 15.2 12.7 1.3 5.4 3.5 3.6 0.1 111.5 2.1 0.2 0.1 0.0 3.4 2.6 6.8 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 1.0 0.2 0.0 0.1 5.1 4.7 4.0 7.8 3.7 5.1 5.0 4.7 5.0 4.1 6.0 4.0 1054.7 12.8 41.1 0.3 32.2 436.0 284.3 143.0 832.1 0.5 206.7 205.0 70.3 35.8 71.5 1.8 8.4 49.1 15.0 789.2 1.9 24.4 263.1 154.1 216.0 336.6 123.8 4.8 0.0 38.7 75.5 463.2 537.2 297.4 54.7 4.7 216.0 4.6 89.9 0.0 0.2 710.9 83.4 232.9 282.0 163.0 143.8 401.0 206.3 16.9 36.8 2.0 0.0 0.0 0.0 49.3 540.9 60.5 38.3 187.3 198.0 2.1 46.4 2.0 39.5 463.7 130.0 21.6 15.9 639.9 674.0 107.9 26.8 63.5 332.6 236.8 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Basal keratinocytes: 5.0;Basal squamous epithelial cells: 4.6;Breast glandular cells: 9.4;Breast myoepithelial cells: 10.4;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 10.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.0;CAPAN-2: 8.0;HaCaT: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 7.1 0.1 8.4 0.1 9.2 0.3 11.2 0.9 7.4 19.7 1.0 0.1 0.5 0.7 0.2 94.7 16.3 1.3 0.2 6.5 1.4 12.1 0.1 3.1 0.0 4.3 1.4 0.1 0.1 0.3 0.7 0.0 4.9 0.1 0.0 0.1 21.6 0.2 1.0 201.2 0.0 0.2 2.1 0.8 0.3 0.3 7.4 0.9 0.2 0.0 10.9 0.0 30.9 3.0 5.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.8 8.0 0.0 1.1 0.0 0.1 31.7 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 8.4 9.2 0.9 7.4 6.5 1.4 4.3 1.4 4.9 2.1 7.4 3.0 0.0 6.4 1.1 0.0 0.0 5.0 0.1 0.5 4.6 0.0 9.4 10.4 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 5.9 10.7 0.0 0.1 0.0 0.1 2.7 KREMEN2 "KRM2, MGC10791" ENSG00000131650 "Kringle containing transmembrane protein 2" Q8NCW0 16 2964216-2968383 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 4.1;skin 1: 7.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.1;Basal squamous epithelial cells: 23.3;Intestinal goblet cells: 14.0;Rod photoreceptor cells: 10.9;Spermatocytes: 9.7;Spermatogonia: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.2;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 29.3;MCF7: 15.0;RPMI-8226: 28.8;T-47d: 14.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003223 Uncertain Approved Nucleoli "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoli "HPA003223: AB_1079217" "unprognostic (8.36e-2)" "unprognostic (4.65e-1)" "unprognostic (6.24e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (4.02e-3)" "prognostic unfavorable (8.98e-4)" "unprognostic (3.34e-2)" "unprognostic (1.57e-2)" "unprognostic (8.03e-2)" "unprognostic (8.57e-2)" "unprognostic (7.79e-12)" "unprognostic (6.69e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-2)" "unprognostic (6.58e-3)" 0.1 0.1 0.7 0.3 0.7 0.7 0.1 0.0 0.6 1.5 0.0 0.3 0.1 0.1 0.1 2.0 0.3 0.1 0.0 1.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.0 4.1 0.4 0.0 0.3 7.7 0.6 0.0 0.0 0.2 0.2 1.7 0.0 2.1 0.0 0.0 0.8 0.0 0.5 0.1 1.8 1.1 0.4 10.2 0.0 0.0 1.5 0.6 0.0 0.0 0.0 4.2 1.5 7.8 2.1 0.0 1.1 8.6 1.3 0.7 0.0 1.1 1.2 0.5 2.9 2.6 0.0 0.6 29.3 0.2 0.0 0.0 0.1 0.9 0.0 0.8 3.3 2.9 0.0 15.0 1.8 3.5 2.9 3.0 2.2 4.7 11.8 28.8 0.1 0.3 2.9 1.8 2.0 4.7 5.2 0.4 14.9 2.8 0.2 0.9 12.2 1.0 0.7 5.3 1.3 4.7 0.4 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.7 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.4 14.1 0.9 0.3 23.3 0.4 1.0 0.9 0.9 0.0 0.0 0.0 6.2 0.2 0.0 1.1 0.0 0.1 0.7 0.4 0.1 0.1 0.0 0.0 0.4 2.7 1.8 0.1 0.0 0.9 4.5 0.0 0.0 0.0 0.1 0.0 0.1 14.0 0.0 0.0 0.6 0.6 0.0 0.2 3.6 0.0 0.1 0.5 0.0 0.0 0.0 0.2 1.3 0.0 0.1 2.1 0.5 0.0 0.0 10.9 0.0 0.0 0.3 9.7 18.0 1.2 5.5 0.1 0.6 0.0 0.5 0.4 KRT12 K12 ENSG00000187242 "Keratin 12" Q99456 17 40861303-40867223 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 1.0" "Group enriched" "Detected in some" 5 "Distal enterocytes: 3.9;Paneth cells: 12.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055217, HPA055835" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055217: AB_2682742, HPA055835: AB_2682935" "unprognostic (1.89e-1)" "unprognostic (2.40e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-1)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.74e-2)" "unprognostic (5.52e-2)" "unprognostic (9.41e-3)" "unprognostic (3.49e-1)" "unprognostic (1.73e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-4)" "unprognostic (6.31e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 147.7;skin 1: 172.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1328.6;Cytotrophoblasts: 679.8;Prostatic glandular cells: 2203.0;Syncytiotrophoblasts: 3890.8;Urothelial cells: 1590.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "HBEC3-KT: 9.6;Hep G2: 11.0;SuSa: 7.1;T-47d: 16.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 590000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: AB_1852226, HPA016959: AB_1852228" "unprognostic (1.62e-1)" "unprognostic (5.29e-2)" "unprognostic (4.35e-2)" "unprognostic (6.18e-3)" "unprognostic (1.45e-2)" "unprognostic (2.83e-1)" "unprognostic (5.22e-2)" "unprognostic (6.84e-3)" "unprognostic (2.74e-1)" "unprognostic (2.15e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (8.22e-2)" "unprognostic (6.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (8.26e-4)" 0.4 0.0 0.0 0.3 0.0 1.1 15.7 0.0 0.0 6.8 0.0 0.1 0.2 1.1 2.1 6.5 3.0 1.5 0.2 0.0 0.0 0.6 1.0 1.4 0.0 0.0 0.0 0.1 3.6 0.1 2.8 15.6 0.0 20.7 0.0 0.6 147.7 0.4 0.3 172.3 0.2 0.0 0.0 3.0 0.2 21.7 0.0 0.4 0.1 0.4 2.5 4.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.0 9.6 0.0 0.0 0.0 0.0 0.1 11.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 7.1 16.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.3 0.3 4.6 1328.6 242.1 0.6 0.0 78.0 27.9 0.4 12.8 390.5 3.7 0.0 679.8 1.1 0.1 1.9 462.9 66.2 49.8 7.8 15.1 7.1 0.0 0.5 0.8 109.3 15.0 0.0 66.4 0.0 0.0 0.0 0.0 63.8 0.0 0.3 0.7 57.0 0.0 0.7 10.6 0.6 3.0 5.4 0.0 5.4 15.8 0.0 0.5 0.3 17.7 1.1 0.7 0.0 2203.0 0.0 0.4 275.0 0.2 0.0 0.0 48.4 62.1 0.7 7.9 8.1 3890.8 7.6 0.1 0.9 1590.3 KRT32 "Ha-2, KRTHA2" ENSG00000108759 "Keratin 32" Q14532 17 41459513-41467386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.9;skin 1: 19.5" "Group enriched" "Detected in some" 6 "Basal squamous epithelial cells: 21.6;Squamous epithelial cells: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-RPE1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 210000000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.39e-2)" "unprognostic (3.29e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "unprognostic (2.32e-2)" "unprognostic (2.67e-3)" "unprognostic (2.72e-9)" "unprognostic (1.31e-2)" "unprognostic (1.77e-1)" 0.6 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.8 21.6 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.4 0.0 0.4 KRT80 KB20 ENSG00000167767 "Keratin 80" Q6KB66 12 52168996-52192014 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 219.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.9;Ductal cells: 63.0;Endometrial ciliated cells: 33.0;Glandular and luminal cells: 33.5;Pancreatic endocrine cells: 48.4;Suprabasal keratinocytes: 37.4;Syncytiotrophoblasts: 58.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 202.5;MCF7: 287.3;SK-BR-3: 127.7;U-2 OS: 174.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA077836, HPA077918" Enhanced "Intermediate filaments" No No 230000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Intermediate filaments" "HPA077836: AB_2686857, HPA077918: AB_2686871" "prognostic unfavorable (1.05e-4)" "unprognostic (5.45e-3)" "unprognostic (5.35e-2)" "unprognostic (9.19e-3)" "unprognostic (2.85e-4)" "unprognostic (6.68e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-3)" "unprognostic (5.60e-2)" "unprognostic (4.06e-2)" "unprognostic (7.06e-3)" "unprognostic (1.02e-1)" "unprognostic (8.79e-3)" "unprognostic (8.85e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.98e-2)" 0.4 5.3 0.0 0.3 0.0 0.1 8.7 0.3 0.6 18.5 0.0 0.1 0.5 1.2 0.9 51.0 3.4 2.7 0.3 0.1 0.0 2.7 0.7 3.4 0.0 0.0 0.0 0.2 11.6 7.0 0.4 7.3 0.0 1.5 0.1 0.5 24.8 3.4 1.3 219.1 0.3 0.1 0.0 0.1 0.5 0.3 0.0 0.8 0.8 0.0 41.1 9.9 36.5 0.0 202.5 66.7 0.0 0.0 0.0 0.0 54.2 2.9 1.8 15.3 4.6 4.5 85.9 0.0 94.4 2.3 99.4 98.5 0.0 1.3 5.3 0.4 0.0 0.0 99.4 2.4 10.1 0.1 0.1 1.1 11.9 3.5 23.0 70.2 23.2 0.0 0.0 0.1 5.4 287.3 0.2 0.1 0.4 58.5 10.1 0.2 79.4 3.0 87.1 35.7 24.5 1.3 50.1 127.7 1.2 5.6 24.1 1.0 13.5 0.3 174.4 0.2 71.6 0.1 0.3 0.5 18.0 7.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 6.2 3.9 4.4 0.0 0.0 14.7 4.6 0.4 10.0 9.4 11.0 0.0 25.9 0.1 0.3 0.0 63.0 0.9 33.0 3.7 0.5 0.0 0.0 0.1 20.4 3.4 0.4 0.0 33.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.1 12.2 0.0 1.6 0.5 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 48.4 0.0 0.0 0.0 4.8 0.1 1.8 21.7 0.0 0.0 0.4 2.2 0.1 0.0 2.9 37.4 58.3 0.3 0.3 0.3 8.5 KRT84 "Hb-4, KRTHB4" ENSG00000161849 "Keratin 84" Q9NSB2 12 52377812-52385652 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 1.5;skin 1: 1.9" "Cell type enriched" "Detected in single" 22 "Cardiomyocytes: 2.2" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039714 Supported NA NA 67000000 "Cluster 31: Skin - Epidermis development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA039714: AB_2676641" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP19-3 KAP19.3 ENSG00000244025 "Keratin associated protein 19-3" Q7Z4W3 21 30491462-30492013 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 89 "skeletal muscle: 6.7;skin 1: 15.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP5-8 "KRTAP5-2, KRTAP5.8, UHSKerB" ENSG00000241233 "Keratin associated protein 5-8" O75690 11 71538025-71539209 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 6.0;skin 1: 7.6" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Cancer enhanced" "Detected in single" "renal cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (9.72e-2)" "unprognostic (8.49e-2)" "unprognostic (9.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-2)" "unprognostic (1.99e-1)" "unprognostic (6.92e-2)" "unprognostic (2.89e-2)" "unprognostic (2.42e-2)" "unprognostic (2.08e-1)" "unprognostic (3.02e-2)" "unprognostic (1.14e-1)" "unprognostic (3.62e-2)" "unprognostic (2.21e-3)" 0.1 0.1 0.4 0.0 0.5 0.0 0.1 0.3 0.8 0.1 0.2 0.1 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.4 0.4 6.0 0.2 0.1 0.0 0.4 0.4 0.0 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.1 7.6 0.1 0.0 0.3 0.1 0.0 1.4 0.5 0.0 0.0 0.0 0.0 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.8 0.4 0.4 0.4 0.4 0.5 0.3 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 171.0;Gastric mucus-secreting cells: 138.1;Pancreatic endocrine cells: 585.5;Paneth cells: 170.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 1237.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 1800000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" 10.0 1.2 8.3 8.5 3.6 0.1 20.3 2.8 5.9 15.4 5.4 13.6 17.8 15.6 4.7 14.5 12.0 7.4 4.2 4.1 3.5 3.2 1.7 20.9 4.1 3.8 5.9 5.7 4.7 10.9 3.0 24.8 3.6 12.2 8.4 3.7 21.3 13.5 2.0 32.1 19.7 6.9 3.5 0.8 31.8 3.3 4.3 9.5 2.3 1.7 4.1 12.2 23.1 2.9 140.5 15.7 0.1 0.1 6.9 1.3 0.3 2.6 1.8 1.3 1.7 5.4 159.5 0.1 17.3 1.8 0.4 248.5 0.2 1237.9 0.9 0.2 8.8 0.0 5.6 2.8 1.2 0.0 0.6 1.6 139.1 0.8 140.0 0.9 5.2 0.2 0.0 0.2 1.6 0.4 0.1 0.1 1.4 42.6 14.4 2.6 0.1 0.2 51.8 15.4 0.6 2.5 4.9 2.0 0.4 0.3 4.5 1.8 12.3 0.9 1.0 6.7 0.6 0.2 0.1 0.6 2.9 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.3 3.6 2.8 5.9 4.1 3.5 3.8 5.9 3.6 3.5 4.3 2.9 28.8 115.4 26.4 13.1 0.7 31.4 104.2 117.1 100.7 6.0 21.8 41.8 2.3 4.3 20.4 1.8 0.0 0.6 0.5 171.0 0.0 30.2 3.9 21.5 4.3 7.5 8.3 0.0 8.3 34.4 0.4 3.6 138.1 24.0 5.7 9.5 2.5 0.9 0.2 0.0 18.5 23.7 4.1 0.0 1.5 4.5 5.9 2.0 1.8 68.4 0.6 0.2 0.0 1.0 2.0 585.5 170.1 3.4 0.2 45.6 39.5 0.0 15.6 2.2 6.6 1.5 22.1 4.5 4.0 28.2 9.9 0.1 1.5 5.9 28.4 18.2 LGALS7 "GAL7, LGALS7A, PIG1, TP53I1" ENSG00000205076 "Galectin 7" P47929 19 38770971-38773492 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 393.1;skin 1: 877.2" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 275.1;Squamous epithelial cells: 639.7;Suprabasal keratinocytes: 725.7" "Group enriched" "Detected in many" 7 "cervical cancer: 32.0;head and neck cancer: 64.8;melanoma: 27.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 7.1;OE19: 2.2" "Low region specificity" "Detected in single" "HPA001549, CAB032606" Enhanced "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB032606: AB_640852, HPA001549: AB_1078938" "unprognostic (1.56e-2)" "unprognostic (1.30e-2)" "unprognostic (1.18e-2)" "unprognostic (4.86e-2)" "unprognostic (2.39e-1)" "unprognostic (2.38e-1)" "unprognostic (2.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.01e-2)" "unprognostic (3.37e-1)" "unprognostic (1.93e-1)" "unprognostic (3.31e-2)" "unprognostic (3.09e-2)" 1.0 0.2 0.0 0.0 0.0 0.0 13.6 0.0 0.0 63.2 0.0 0.3 0.0 0.4 0.0 393.1 0.4 0.2 0.5 0.0 0.1 0.7 0.3 0.4 0.0 0.1 0.1 0.3 0.4 0.0 0.4 0.0 0.1 2.0 0.0 0.0 25.5 0.2 10.7 877.2 0.2 0.0 0.0 2.3 0.5 1.5 0.0 0.5 0.7 0.4 2.2 0.3 155.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 275.1 0.9 124.3 89.4 0.0 0.3 2.8 0.2 0.0 57.6 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 7.5 1.1 0.0 0.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 1.6 0.0 0.4 10.7 0.0 0.0 1.7 3.8 1.5 0.8 639.7 725.7 0.0 0.5 0.1 0.0 1.5 LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6695.7" "Group enriched" "Detected in many" 10 "Basal keratinocytes: 1529.6;Suprabasal keratinocytes: 5136.5" "Cancer enhanced" "Detected in many" "cervical cancer: 142.7;head and neck cancer: 185.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HaCaT: 3.9;OE19: 3.9" "HPA001549, CAB025100" Supported "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB025100: , HPA001549: AB_1078938" "unprognostic (4.20e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-2)" "unprognostic (3.66e-3)" "unprognostic (6.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-3)" 6.1 1.0 0.0 0.0 0.0 0.1 7.3 0.0 0.0 490.5 0.0 1.8 0.0 1.0 0.0 1463.3 0.9 0.0 2.6 0.0 0.0 2.1 3.0 2.6 0.0 0.0 0.0 1.4 2.7 0.0 2.2 0.0 0.0 5.0 0.0 0.0 167.2 0.1 10.2 6695.7 1.7 0.0 0.0 22.0 3.0 4.9 0.0 0.2 2.3 0.0 1.6 1.0 834.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1529.6 6.3 253.5 102.4 0.0 1.2 13.3 0.4 0.0 64.4 1.8 0.0 0.0 0.0 0.3 0.0 0.0 5.4 3.1 0.2 3.2 1.2 0.0 0.0 0.2 0.1 3.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 41.3 12.3 0.0 0.3 44.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 2.1 0.3 0.3 9.3 0.0 0.0 1.3 4.2 7.5 1.9 329.6 5136.5 0.0 1.6 0.4 0.1 14.0 LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSG00000160789 "Lamin A/C" P02545 1 156082573-156140081 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Charcot-Marie-Tooth disease, Congenital muscular dystrophy, Disease variant, Emery-Dreifuss muscular dystrophy, Limb-girdle muscular dystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 1533.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 85.1;T-reg: 83.2" "Group enriched" "Detected in all" 8 "dendritic cells: 85.1;granulocytes: 23.9;T-cells: 83.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004022, HPA006523, HPA006660" Supported Supported "Nuclear speckles" NA NA 5700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB004022: AB_2136278, HPA006523: , HPA006660: AB_1079231" "unprognostic (2.22e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-2)" "unprognostic (5.75e-2)" "unprognostic (7.43e-3)" "unprognostic (1.47e-1)" "unprognostic (5.23e-3)" "unprognostic (3.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.90e-2)" "unprognostic (5.10e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-1)" "unprognostic (3.08e-2)" "unprognostic (1.44e-2)" 280.2 174.8 17.6 64.9 27.1 58.1 231.5 24.1 20.6 221.7 33.0 183.3 72.8 271.4 14.5 256.2 173.8 92.1 221.7 15.8 23.1 120.9 93.2 188.5 18.2 30.3 25.2 178.2 81.8 21.3 76.9 53.0 26.1 125.3 38.2 4.7 176.1 42.8 190.0 364.3 136.8 78.8 21.0 84.1 160.6 61.9 30.9 15.3 147.4 23.8 22.9 168.7 217.6 41.8 518.8 269.7 26.2 72.4 119.5 238.7 169.4 607.3 379.6 221.3 146.8 68.3 311.9 2.8 338.7 417.9 94.6 515.4 31.4 227.8 70.3 188.6 50.8 175.4 168.4 130.8 124.0 25.7 412.9 133.0 92.0 154.8 134.7 120.2 207.5 0.7 82.8 21.9 205.8 193.1 1.0 67.8 32.1 202.9 706.0 1.6 195.9 137.7 128.9 105.6 33.8 114.9 414.3 154.2 427.4 56.2 230.1 74.2 727.9 241.6 233.0 389.1 393.3 39.5 10.5 4.9 449.2 24.8 760.4 23.9 8.3 0.4 2.8 2.1 2.5 2.4 17.8 7.3 85.1 0.2 0.2 0.7 2.1 3.7 0.2 0.3 83.2 14.6 17.6 27.1 24.1 20.6 15.8 23.1 30.3 25.2 26.1 21.0 30.9 41.8 353.5 262.8 350.0 16.0 179.1 610.5 1235.3 446.2 531.6 7.2 542.5 374.9 94.1 191.6 320.3 161.8 47.9 478.8 239.8 614.1 109.5 429.3 38.6 215.4 209.4 386.0 431.5 70.4 9.9 360.2 387.8 622.1 505.1 270.5 1181.8 145.5 277.7 103.1 343.0 13.5 15.1 601.2 177.0 60.6 1533.4 45.4 288.6 409.0 859.2 10.3 20.4 37.2 3.1 17.1 20.1 513.0 384.1 287.3 331.3 340.6 262.6 125.0 170.5 17.8 203.8 1028.4 766.8 107.4 42.2 404.1 602.4 680.9 472.3 111.6 513.8 942.6 LONRF1 "FLJ23749, RNF191" ENSG00000154359 "LON peptidase N-terminal domain and ring finger 1" Q17RB8 8 12721906-12756073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023584, HPA024814" Uncertain Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Centrosome "HPA023584: AB_1853233, HPA024814: AB_1853235" "unprognostic (2.59e-1)" "unprognostic (2.17e-3)" "unprognostic (1.35e-2)" "unprognostic (3.56e-1)" "unprognostic (9.09e-2)" "unprognostic (3.96e-3)" "unprognostic (3.13e-1)" "unprognostic (5.78e-2)" "unprognostic (2.74e-3)" "unprognostic (1.18e-1)" "unprognostic (5.83e-2)" "unprognostic (3.39e-1)" "unprognostic (5.46e-3)" "unprognostic (8.97e-2)" "unprognostic (8.90e-2)" "unprognostic (3.08e-3)" "unprognostic (1.15e-1)" 16.2 5.8 2.8 4.5 2.7 5.9 10.5 3.4 3.7 11.4 1.3 7.7 2.3 11.3 9.6 13.0 10.5 9.5 4.9 3.0 2.3 6.3 9.9 7.3 7.1 2.2 2.1 15.2 7.5 8.0 3.8 10.1 1.9 10.7 4.3 7.9 8.0 10.6 17.2 28.7 4.5 9.2 2.3 8.4 5.4 15.8 2.6 6.8 8.7 11.3 8.1 7.9 8.3 3.0 1.2 3.0 15.0 4.6 15.6 7.4 10.0 3.8 6.3 4.1 5.7 0.9 3.9 24.0 0.9 6.7 12.9 1.8 12.0 4.7 4.6 3.7 6.8 7.9 0.5 6.2 14.4 2.1 3.0 7.0 8.2 2.6 8.9 3.8 6.4 9.7 1.1 56.6 2.7 4.2 10.4 7.0 15.5 4.8 0.9 5.8 10.2 4.3 3.5 10.2 31.2 3.6 2.2 5.1 29.8 10.7 1.0 10.4 2.9 2.2 3.7 8.9 3.0 4.3 20.7 12.4 12.0 7.2 7.0 0.0 0.1 0.6 0.1 0.5 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 2.8 2.7 3.4 3.7 3.0 2.3 2.2 2.1 1.9 2.3 2.6 3.0 18.9 9.6 16.3 23.2 25.2 60.8 32.8 7.8 52.3 25.1 15.1 10.3 9.7 10.0 13.1 11.0 16.7 3.6 6.3 4.3 7.9 5.3 57.4 12.1 27.9 15.1 2.4 4.6 67.0 4.0 8.2 24.2 5.6 28.3 6.3 27.8 6.1 14.7 5.6 8.4 43.6 6.4 4.1 9.5 27.6 53.5 29.2 17.2 44.4 21.5 3.6 8.3 0.0 42.7 14.9 4.3 6.4 19.9 16.3 26.4 3.8 6.0 8.7 13.0 19.7 36.7 32.7 8.2 19.7 26.4 73.6 7.3 9.7 3.4 5.8 30.1 LRIG3 "FLJ90440, KIAA3016" ENSG00000139263 "Leucine rich repeats and immunoglobulin like domains 3" Q6UXM1 12 58872149-58920504 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.8;Basal squamous epithelial cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 49.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010773 Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA010773: AB_1853275" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-2)" "unprognostic (3.88e-2)" "unprognostic (2.53e-1)" "unprognostic (3.46e-2)" "unprognostic (1.83e-2)" "unprognostic (1.34e-3)" "unprognostic (1.21e-1)" "unprognostic (1.92e-1)" "unprognostic (3.04e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-3)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-2)" 20.8 2.6 3.5 6.7 4.3 0.1 18.8 2.6 3.3 21.0 11.2 18.6 14.2 12.5 10.6 22.3 14.3 17.7 5.3 3.7 3.0 10.3 10.3 10.4 4.3 4.2 5.4 22.4 18.9 9.1 7.1 11.5 3.4 10.5 25.6 1.8 32.9 10.4 4.0 35.9 13.4 15.4 4.5 8.7 17.9 3.3 4.1 12.2 58.2 7.8 9.6 18.6 18.5 7.6 3.9 3.6 13.6 1.0 24.2 28.0 3.1 9.2 26.4 8.7 9.3 10.9 5.0 3.7 18.3 10.3 10.5 17.9 5.1 23.3 6.3 28.1 17.8 0.9 6.3 5.4 4.7 1.6 0.4 27.9 49.8 9.3 19.8 16.9 24.1 4.2 0.2 4.5 5.8 1.8 4.5 0.1 14.4 4.6 5.5 0.0 11.5 9.2 6.7 19.8 13.8 0.0 8.1 5.0 8.6 19.0 9.3 0.2 10.4 11.8 8.1 7.1 12.2 1.9 0.0 0.0 2.5 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.3 2.6 3.3 3.7 3.0 4.2 5.4 3.4 4.5 4.1 7.6 17.1 16.0 24.6 17.9 0.1 22.4 8.2 42.8 44.9 3.8 6.3 10.3 3.7 34.3 23.0 1.8 0.0 0.8 0.5 24.5 0.0 11.8 0.3 8.2 37.0 16.2 11.5 0.0 1.8 18.1 0.5 19.6 23.4 4.6 0.0 0.1 12.1 7.3 2.6 3.3 6.0 11.4 16.2 0.3 8.2 1.8 27.1 0.4 3.6 9.4 0.0 3.4 0.0 3.5 22.4 7.4 15.6 29.0 1.8 4.4 8.7 4.9 14.1 0.2 6.6 10.6 11.3 0.5 2.0 25.3 22.4 0.3 1.0 15.0 31.5 4.7 LRRC15 LIB ENSG00000172061 "Leucine rich repeat containing 15" Q8TF66 3 194355249-194369743 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.9;skin 1: 7.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.9;Endothelial cells: 1.0;Fibroblasts: 2.3;Hepatic stellate cells: 1.8;Langerhans cells: 3.0;Suprabasal keratinocytes: 1.4" "Cancer enhanced" "Detected in many" "breast cancer: 25.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "fHDF/TERT166: 120.6;U-87 MG: 62.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA035503 Uncertain Approved "Vesicles,Plasma membrane" NA NA 1700000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA035503: AB_10961253" "unprognostic (3.20e-2)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (6.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (3.53e-2)" "unprognostic (3.97e-2)" "unprognostic (1.88e-3)" "unprognostic (1.22e-8)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (5.62e-3)" "unprognostic (7.54e-3)" 1.1 0.1 0.0 1.3 0.0 0.0 3.7 0.0 0.0 2.9 0.0 1.7 0.5 1.9 0.0 0.5 1.1 1.6 0.2 0.0 0.0 0.0 0.1 2.0 0.8 0.0 0.1 0.2 0.1 0.1 0.0 2.2 0.0 0.1 3.0 0.0 1.0 0.0 0.1 7.3 0.4 0.6 0.0 1.3 1.5 0.0 0.1 0.2 1.3 0.2 4.9 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.7 0.1 0.1 0.4 0.0 0.0 1.0 120.6 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 22.5 3.7 3.0 0.0 0.0 0.0 0.0 62.7 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 33.0;Late spermatids: 81.8;Melanocytes: 17.8;Syncytiotrophoblasts: 21.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.5;BEWO: 5.0;HaCaT: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" 1.1 0.6 2.6 1.4 2.5 0.1 2.9 1.8 6.0 9.3 0.0 2.3 0.1 0.9 1.4 11.4 0.8 1.1 1.5 3.0 2.9 3.0 0.4 4.0 0.7 6.8 3.2 0.4 0.3 0.6 1.6 1.0 6.6 1.3 0.8 2.0 3.1 0.8 0.2 50.6 1.2 1.1 1.7 4.8 1.0 3.8 4.1 0.9 1.4 0.4 1.7 1.9 9.0 4.1 3.5 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.0 0.5 0.6 0.4 1.2 0.2 0.7 0.4 1.4 5.2 0.0 0.7 0.3 0.6 0.0 0.1 0.4 0.0 1.5 0.1 0.0 1.7 1.5 0.2 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.3 1.9 1.2 0.0 0.0 0.0 0.3 0.6 0.2 0.1 0.7 0.7 0.0 1.1 0.4 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.1 2.6 2.5 1.8 6.0 3.0 2.9 6.8 3.2 6.6 1.7 4.1 4.1 0.5 0.0 0.0 4.6 0.0 3.6 2.6 1.6 4.0 1.4 1.8 1.5 0.7 0.0 0.4 0.0 0.0 1.6 0.1 3.7 3.9 0.6 33.0 0.2 0.1 3.1 0.0 0.0 7.7 0.9 8.4 1.2 0.0 0.2 0.0 0.5 0.7 0.0 2.4 0.0 8.8 1.9 0.0 0.6 0.8 81.8 0.3 0.5 17.8 1.0 0.0 0.9 0.0 9.5 7.8 0.3 2.3 1.2 0.0 1.4 0.2 0.0 1.4 0.9 0.0 1.0 0.2 9.9 2.6 3.7 2.8 21.6 0.1 0.1 0.8 6.2 LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 95.5" "Cell type enhanced" "Detected in many" "Early spermatids: 245.7;Gastric mucus-secreting cells: 87.7;Inhibitory neurons: 77.8;Late spermatids: 118.5;Suprabasal keratinocytes: 69.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 64.8;LHCN-M2: 102.3;NB-4: 34.7;RT4: 54.7;SK-BR-3: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "HPA049239: AB_2680688" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (3.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (2.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-3)" "unprognostic (2.59e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-3)" 0.3 0.2 3.5 0.4 2.5 0.2 16.4 1.6 5.3 2.8 1.6 1.7 2.6 0.9 1.2 4.1 23.4 37.3 0.0 4.3 4.1 20.5 0.9 1.7 0.4 2.3 7.3 0.4 12.3 16.1 0.4 0.8 3.0 11.1 3.3 1.0 5.8 15.2 0.2 95.5 1.2 0.3 1.9 2.8 41.3 34.1 8.0 0.3 0.2 0.0 1.9 14.2 6.3 2.1 1.4 0.0 0.0 1.5 0.0 0.1 0.1 8.0 1.5 6.6 2.5 1.0 0.0 0.0 0.0 64.8 0.0 14.0 1.5 1.3 20.6 0.0 7.4 0.0 1.9 0.0 0.2 0.0 0.1 0.6 21.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 102.3 24.3 0.0 34.7 2.0 14.6 0.3 0.0 0.4 4.3 3.2 54.7 3.9 0.1 0.4 32.1 0.0 6.3 4.8 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.8 13.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 2.5 1.6 5.3 4.3 4.1 2.3 7.3 3.0 1.9 8.0 2.1 0.5 0.0 2.0 2.3 5.5 29.8 21.0 30.6 6.2 0.0 23.4 17.1 1.4 42.9 23.9 46.0 0.0 0.1 0.1 4.0 7.9 12.4 245.7 5.2 0.3 1.0 2.4 2.7 4.6 19.1 0.7 0.8 87.7 5.7 0.0 0.4 0.0 0.1 0.1 0.0 77.8 3.9 8.2 0.0 2.8 118.5 2.1 0.4 5.4 0.0 0.6 0.0 0.0 0.0 0.4 30.9 6.0 0.0 4.5 40.6 5.7 0.2 21.4 0.0 0.0 0.0 1.3 4.2 1.7 3.5 69.0 0.3 1.1 0.0 3.5 53.7 LYSMD4 FLJ33008 ENSG00000183060 "LysM domain containing 4" Q5XG99 15 99715697-99733561 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029152, HPA059824" Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Cytosol "Actin filaments" "HPA029152: AB_10602033, HPA059824: AB_2684135" "unprognostic (2.43e-3)" "unprognostic (1.30e-2)" "unprognostic (1.53e-1)" "unprognostic (2.81e-1)" "unprognostic (4.07e-3)" "unprognostic (3.80e-2)" "unprognostic (1.53e-3)" "unprognostic (3.75e-1)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (6.35e-3)" "unprognostic (9.77e-2)" "unprognostic (1.02e-2)" "unprognostic (2.06e-1)" "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (3.30e-1)" 7.1 5.5 6.3 1.7 6.8 3.1 6.7 6.3 7.1 8.4 6.2 9.7 4.8 9.4 3.4 11.1 8.1 1.5 20.2 6.4 6.0 11.8 11.8 7.6 2.3 5.9 6.4 8.9 8.0 5.7 7.1 2.8 6.2 9.5 3.2 5.2 9.5 4.2 10.3 16.7 7.9 3.8 5.9 8.0 7.8 7.7 7.0 3.9 5.0 5.9 3.8 7.9 9.4 6.8 3.5 3.3 6.5 3.8 7.1 6.4 3.9 3.9 2.7 3.3 4.8 8.2 3.0 3.8 2.3 3.6 5.8 10.1 5.1 6.3 3.8 0.8 9.2 2.5 7.2 5.7 4.1 1.8 4.6 3.7 9.2 3.0 3.6 2.0 4.5 10.9 6.2 4.8 2.2 4.1 4.8 5.1 4.3 9.7 3.7 3.4 4.6 1.9 5.9 9.0 3.7 3.3 7.2 2.2 3.9 8.3 1.5 3.5 5.8 2.7 7.3 3.7 1.7 6.3 9.1 3.1 3.5 4.5 2.9 0.0 1.3 5.3 2.1 1.9 1.7 1.0 3.0 2.6 0.6 1.7 3.5 1.6 0.4 0.7 2.7 3.0 3.2 2.4 6.3 6.8 6.3 7.1 6.4 6.0 5.9 6.4 6.2 5.9 7.0 6.8 7.0 6.4 3.3 4.6 2.5 8.7 8.1 4.6 8.0 8.0 3.5 6.3 12.8 7.2 3.9 3.7 10.4 2.6 4.9 4.4 1.9 4.1 7.3 1.3 3.0 4.8 3.0 6.1 9.8 9.7 2.0 6.8 3.6 1.7 0.0 2.9 3.9 3.4 4.3 10.1 11.4 6.2 6.1 2.2 3.7 8.1 5.3 3.9 1.8 8.4 8.1 11.6 3.1 6.0 7.4 7.2 3.0 6.8 3.9 2.1 3.9 5.3 2.5 10.0 13.1 3.9 5.7 12.7 11.3 8.1 9.1 1.4 2.9 2.2 2.6 3.5 MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 20.6;Basal keratinocytes: 18.4;Basal squamous epithelial cells: 23.3;Melanocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 51.1;HeLa: 56.3;hTERT-RPE1: 69.7;U-2197: 55.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" Yes No 1700000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" 25.9 4.3 2.9 3.9 2.7 10.8 20.0 2.6 2.8 14.5 1.4 14.1 2.1 9.6 1.4 13.2 28.9 11.2 14.2 1.9 3.2 5.9 5.0 22.1 5.5 3.5 5.8 18.0 6.5 0.4 4.1 2.8 3.6 26.5 1.1 1.8 19.3 4.7 4.8 44.6 10.0 1.4 2.1 10.7 10.1 3.3 3.7 3.4 11.6 1.9 3.4 11.0 22.8 1.9 11.6 14.1 4.3 6.6 0.4 0.3 1.0 51.1 14.1 5.2 1.6 3.3 10.4 0.0 13.8 24.6 4.4 6.7 0.0 0.5 1.7 0.0 0.4 0.0 56.3 3.3 0.0 0.2 0.9 0.1 0.6 0.4 0.8 69.7 5.6 0.1 0.0 0.0 0.1 6.0 0.0 10.9 2.7 3.3 0.9 2.2 3.0 6.2 1.1 3.8 3.8 3.1 18.8 1.1 6.4 11.4 4.9 1.5 2.2 19.6 1.7 55.6 3.9 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.8 0.0 0.0 0.0 0.8 0.1 2.9 2.7 2.6 2.8 1.9 3.2 3.5 5.8 3.6 2.1 3.7 1.9 5.0 22.4 20.6 8.8 2.7 18.4 7.1 3.9 23.3 0.8 3.6 3.0 3.3 5.7 4.4 1.8 0.0 0.2 0.4 0.6 0.0 3.6 0.2 1.4 0.6 7.0 0.0 4.8 6.5 1.4 1.3 9.4 6.6 5.0 1.3 9.8 16.8 0.9 1.0 0.0 7.2 1.4 0.0 0.3 7.5 0.5 11.5 2.8 19.6 5.6 0.7 14.7 1.0 4.5 5.2 4.5 0.1 3.4 0.4 4.0 0.5 1.2 0.3 1.2 0.0 0.5 2.7 0.3 1.1 7.6 11.4 0.4 3.6 0.1 1.1 2.7 METRNL ENSG00000176845 "Meteorin like, glial cell differentiation regulator" Q641Q3 17 83079609-83095122 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 252.9" "Cell type enhanced" "Detected in many" "dendritic cells: 640.2;Macrophages: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 119.5;U-2197: 162.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023792 Uncertain "Secreted to blood" NA NA 445000 1300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA023792: AB_2144182" "unprognostic (7.99e-2)" "unprognostic (2.32e-1)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (6.41e-3)" "unprognostic (7.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (1.01e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-3)" "unprognostic (4.43e-1)" "unprognostic (2.23e-1)" "unprognostic (2.46e-1)" "unprognostic (1.61e-2)" 105.4 24.0 7.8 13.2 6.9 21.9 66.8 6.7 8.9 89.0 33.4 57.0 26.6 33.8 2.1 184.1 39.3 12.2 95.8 7.2 6.8 71.4 19.1 80.3 5.1 9.6 9.7 23.0 24.4 25.1 36.5 14.5 7.8 26.4 4.1 3.4 52.9 3.7 15.3 252.9 50.0 4.3 7.3 41.0 41.1 32.4 15.1 3.2 61.3 1.5 4.7 47.4 103.4 6.7 11.4 0.3 5.4 7.3 5.9 21.8 26.7 11.7 5.1 8.4 9.6 1.4 7.8 0.7 4.6 9.1 6.4 29.8 1.9 0.7 5.6 8.6 4.4 26.8 32.0 3.3 14.1 7.8 49.5 10.5 2.2 36.1 2.4 5.3 4.2 0.0 17.1 0.0 7.2 19.0 0.7 23.9 1.1 16.6 16.6 8.2 11.4 3.9 1.3 4.3 0.5 3.6 16.0 29.5 14.2 5.3 27.3 8.2 10.9 119.5 12.5 162.6 3.6 0.0 0.0 0.4 28.1 3.1 7.5 6.8 3.2 10.5 1.8 6.0 0.1 1.4 0.3 1.3 4.5 0.1 0.0 0.5 5.5 3.2 8.1 1.7 1.8 1.5 7.8 6.9 6.7 8.9 7.2 6.8 9.6 9.7 7.8 7.3 15.1 6.7 39.0 25.6 31.1 6.5 28.0 22.9 19.9 4.7 1.2 3.3 19.7 16.5 40.5 14.3 12.3 49.7 6.2 12.4 640.2 110.2 3.9 11.5 9.5 72.6 27.1 16.8 6.0 3.2 0.7 13.9 5.1 56.1 18.3 103.4 32.9 41.5 25.0 1.0 53.8 1.7 2.1 41.4 6.1 62.2 133.6 1.5 7.8 162.0 16.0 1.9 13.7 90.6 25.7 4.0 0.3 19.7 64.9 3.4 95.8 18.4 53.4 8.3 7.4 22.2 0.0 75.4 35.5 5.9 3.4 13.5 49.2 19.2 98.8 0.5 35.1 62.2 MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA040913: AB_10962835" "unprognostic (5.81e-3)" "unprognostic (5.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-3)" "unprognostic (5.42e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (5.31e-2)" "unprognostic (7.05e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (8.70e-2)" "unprognostic (6.89e-2)" 6.5 14.4 7.5 11.7 8.2 16.0 18.4 8.0 9.7 7.3 7.9 11.4 13.4 5.2 10.4 13.1 6.2 7.3 10.8 7.2 7.5 12.8 14.4 7.7 19.9 8.6 8.1 5.9 8.8 7.8 4.7 12.8 8.7 7.5 13.4 7.8 9.0 7.4 21.3 34.2 11.9 6.7 8.3 17.7 9.3 10.7 7.9 19.8 11.9 12.1 20.8 8.9 9.5 9.3 44.7 51.0 41.0 38.7 16.5 29.0 54.9 36.8 27.1 34.8 47.4 63.4 44.7 53.4 20.3 16.4 39.6 64.9 43.1 55.1 52.7 19.9 34.7 34.7 29.6 97.2 12.3 22.9 56.2 17.6 37.3 52.3 27.4 16.3 28.2 26.0 48.0 33.3 70.7 33.4 40.5 29.9 36.3 26.8 44.0 30.5 91.4 50.8 30.1 32.3 31.6 26.1 26.1 62.8 57.7 33.2 59.7 15.5 22.8 59.1 48.1 29.8 40.3 24.6 59.6 45.3 15.2 17.3 44.7 57.5 15.2 44.6 8.1 14.9 10.9 21.0 10.5 10.9 12.6 24.2 7.5 6.9 14.4 16.7 15.0 19.5 17.1 8.4 7.5 8.2 8.0 9.7 7.2 7.5 8.6 8.1 8.7 8.3 7.9 9.3 10.6 0.0 10.0 19.9 24.6 46.4 15.7 12.7 40.9 7.9 19.9 39.4 12.6 15.7 11.9 7.3 8.4 22.9 21.0 14.3 39.2 13.1 9.8 11.2 15.6 11.9 7.2 52.6 3.1 10.2 25.9 8.1 5.1 13.3 48.0 25.5 20.0 9.9 31.4 8.4 2.9 12.1 6.1 34.4 15.4 5.5 8.4 18.8 21.4 9.4 16.4 11.4 28.8 17.6 12.6 10.4 10.6 5.7 13.2 12.3 31.0 26.5 5.9 10.0 13.1 10.3 10.8 38.6 47.0 20.5 46.9 18.1 14.9 27.1 19.0 12.8 MINK1 "B55, MAP4K6, MINK, YSK2, ZC3" ENSG00000141503 "Misshapen like kinase 1" Q8N4C8 17 4833340-4898061 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056296 Approved NA NA 26000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA056296: AB_2683090" "unprognostic (2.80e-1)" "unprognostic (3.83e-2)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.88e-1)" "unprognostic (3.26e-3)" "prognostic unfavorable (3.00e-4)" "unprognostic (4.64e-3)" "unprognostic (3.21e-1)" "unprognostic (2.78e-2)" "prognostic favorable (2.77e-4)" "prognostic unfavorable (9.27e-4)" "unprognostic (8.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.47e-2)" "unprognostic (1.62e-1)" 22.8 21.5 32.4 24.9 29.8 22.7 24.7 13.0 34.4 32.0 0.0 36.9 43.0 19.1 5.7 72.1 21.3 18.6 15.4 50.7 15.1 23.0 17.5 35.6 23.9 17.7 16.2 36.9 29.4 23.2 25.7 23.2 15.3 25.5 28.1 18.2 32.4 12.2 12.5 76.9 41.7 14.6 13.4 27.6 29.0 14.2 26.4 16.8 21.9 9.9 18.8 21.8 46.6 20.2 46.9 83.6 20.2 31.2 29.7 21.8 56.0 37.4 34.2 27.6 24.7 32.3 31.3 34.5 41.5 38.2 30.0 91.8 15.5 64.2 20.2 49.0 41.2 23.9 62.8 25.3 18.8 9.1 45.2 22.4 44.1 27.1 25.2 24.9 30.8 10.8 25.6 27.4 22.9 27.8 14.8 20.2 15.6 30.4 28.4 17.9 16.9 20.4 42.2 53.9 20.9 16.6 40.1 30.7 23.9 24.2 27.7 12.2 45.0 29.6 13.7 52.8 35.6 16.8 14.6 7.3 26.7 19.2 20.5 0.0 0.7 2.9 1.0 0.6 1.2 1.1 1.1 0.8 0.5 0.7 0.7 0.3 0.6 0.1 0.3 0.3 1.3 1.2 32.4 29.8 13.0 34.4 50.7 15.1 17.7 16.2 15.3 13.4 26.4 20.2 18.1 0.0 2.0 51.9 12.7 41.0 14.7 22.0 37.5 7.2 17.3 18.8 1.4 22.8 9.9 5.5 39.6 18.9 10.2 47.3 5.9 9.5 3.6 10.6 8.6 15.4 18.7 13.0 25.5 10.5 13.3 8.5 51.0 12.7 8.2 21.1 16.1 9.8 18.3 13.5 24.7 30.3 16.2 12.3 16.7 6.8 16.1 13.9 16.0 37.5 29.5 6.9 9.2 13.0 48.1 14.8 46.7 14.7 9.7 19.9 29.3 13.0 12.8 16.9 13.1 6.9 7.6 5.8 13.8 40.9 60.5 19.6 15.9 28.3 27.4 20.1 MMP27 ENSG00000137675 "Matrix metallopeptidase 27" Q9H306 11 102691487-102705769 "Enzymes, Predicted intracellular proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.7;salivary gland: 1.9;skin 1: 2.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Fibroblasts: 4.2;Langerhans cells: 1.8;Suprabasal keratinocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA069097 Approved "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 50: Fibroblasts - ECM organization" "HPA069097: AB_2686085" "unprognostic (3.99e-2)" "unprognostic (2.37e-4)" "unprognostic (1.25e-3)" "unprognostic (1.63e-1)" "unprognostic (4.60e-1)" 1.2 0.0 0.0 0.0 0.0 1.3 4.7 0.0 0.0 0.2 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.4 2.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 MPIG6B "C6orf25, G6b, G6b-B, NG31" ENSG00000204420 "Megakaryocyte and platelet inhibitory receptor G6b" O95866 6 31718594-31726714 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8;skin 1: 8.3" "Cell type enriched" "Detected in single" 14 "granulocytes: 10.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 14 "HEL: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA054404, HPA073017" Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 330000 "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA054404: , HPA073017: AB_2686566" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (2.93e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" "unprognostic (6.53e-2)" "unprognostic (3.53e-2)" "unprognostic (2.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.71e-2)" 0.5 0.0 0.0 0.1 0.0 1.1 0.4 0.1 0.2 1.0 0.1 0.3 0.1 0.4 0.0 1.6 0.5 0.2 0.8 0.1 0.1 0.1 0.3 3.5 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.2 8.3 0.4 0.0 0.0 4.8 0.3 2.3 0.1 0.0 0.5 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.8 0.0 2.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 MRGPRX2 MRGX2 ENSG00000183695 "MAS related GPR family member X2" Q96LB1 11 19054455-19060717 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Cell type enhanced" "Detected in single" "Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055220 Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA055220: AB_2682743" "unprognostic (1.56e-2)" "unprognostic (1.79e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.3;stomach 1: 42.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Distal enterocytes: 53.9;Gastric mucus-secreting cells: 108.6;Intestinal goblet cells: 25.7;Pancreatic endocrine cells: 31.2;Paneth cells: 30.3;Proximal enterocytes: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 39.3;CAPAN-2: 98.8;HaCaT: 56.3;HBEC3-KT: 59.4;hTCEpi: 83.4;RT4: 67.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" 5.1 0.3 1.1 5.1 1.1 0.2 3.8 1.1 1.7 5.7 1.3 26.5 25.2 1.3 1.2 17.5 1.7 11.4 3.2 1.1 0.9 3.4 1.1 9.5 2.5 0.9 0.8 1.0 5.8 0.1 2.7 0.8 0.9 4.7 20.1 0.2 5.4 1.0 1.3 62.3 23.9 2.0 0.8 1.6 42.6 8.4 0.9 8.8 3.4 0.7 5.6 9.2 11.5 1.0 39.3 14.4 0.1 0.6 0.0 0.0 2.2 0.5 0.1 0.0 0.0 4.1 98.8 1.7 8.8 0.5 0.1 56.3 0.0 59.4 0.0 0.9 1.0 0.1 25.9 0.9 0.9 0.0 1.2 0.3 83.4 0.2 11.7 0.2 0.1 0.2 0.8 0.3 0.0 5.1 0.1 0.1 0.3 33.1 34.6 2.9 0.0 1.1 35.8 67.9 1.0 0.1 11.5 22.6 0.2 0.1 17.7 0.9 0.3 0.0 0.3 0.3 0.1 0.5 0.2 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 1.1 1.1 1.7 1.1 0.9 0.9 0.8 0.9 0.8 0.9 1.0 1.6 25.6 10.3 0.7 1.0 8.8 2.2 14.2 6.8 0.0 2.8 2.5 1.0 0.0 10.6 0.0 0.0 0.1 0.2 53.9 0.0 6.4 15.4 2.9 0.8 0.6 4.2 0.0 1.1 10.0 0.4 0.8 108.6 5.3 0.0 0.1 0.0 0.0 0.1 0.0 1.1 25.7 2.0 0.0 1.4 10.5 0.3 0.5 0.0 1.0 0.6 0.0 1.0 2.0 0.1 31.2 30.3 0.0 0.5 2.2 27.6 0.1 7.6 0.0 0.0 0.5 0.9 1.3 1.5 3.2 4.7 0.0 0.5 0.0 20.1 6.2 MUCL1 SBEM ENSG00000172551 "Mucin like 1" Q96DR8 12 54830518-54896008 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 3241.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4494.5;Breast myoepithelial cells: 1273.2;Melanocytes: 1060.1" "Cancer enriched" "Detected in many" 30 "breast cancer: 298.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;hTCEpi: 1.3;MCF7: 2.1;SK-BR-3: 4.8;SuSa: 3.3" HPA039093 Enhanced "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA039093: AB_10795577" "unprognostic (2.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (8.34e-3)" "unprognostic (5.55e-2)" "unprognostic (2.00e-1)" "unprognostic (3.11e-2)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (9.90e-2)" 35.4 0.4 0.2 1.1 0.4 0.0 3241.2 0.2 0.6 1.3 0.1 1.8 0.0 0.2 1.5 0.4 2.1 0.2 2.6 0.3 0.2 2.3 1.0 1.1 0.1 0.2 0.2 0.3 0.3 0.0 0.3 0.4 0.2 1.1 0.0 0.0 207.3 0.0 1.9 762.2 0.3 0.1 0.2 0.2 0.7 1.2 0.2 2.4 0.2 0.0 0.0 1.2 3.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.8 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.6 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.5 10.4 0.0 1.1 0.0 3.8 188.4 0.4 2.1 0.0 0.0 4494.5 1273.2 0.1 0.0 3.4 0.0 0.0 0.0 12.9 0.0 3.9 0.0 0.0 1.8 0.0 3.4 0.0 0.0 1.4 0.2 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.0 0.0 14.1 0.2 0.0 45.5 1060.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 5.9 0.0 0.1 2.6 0.0 0.0 0.0 6.1 0.2 0.6 0.0 10.1 0.0 2.5 0.1 0.0 3.8 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 254.6;skin 1: 289.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1013.3;Basal prostatic cells: 1080.5;Basal squamous epithelial cells: 1270.8;Squamous epithelial cells: 768.8;Suprabasal keratinocytes: 1070.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 1069.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" 254.6 59.8 2.6 62.3 2.2 53.7 115.8 3.7 3.3 54.4 3.0 57.9 30.6 53.8 3.8 99.5 167.5 83.3 45.5 2.3 6.3 20.0 64.9 47.0 49.4 9.2 5.0 100.0 103.1 7.0 12.3 33.4 6.0 32.7 36.8 0.7 42.2 14.1 50.6 289.1 48.6 54.8 4.5 60.1 70.6 12.5 5.5 47.2 27.0 15.7 39.2 63.2 96.3 4.4 56.8 89.3 9.3 100.9 166.6 209.8 28.4 72.2 31.6 87.5 72.7 137.0 150.2 587.3 86.4 43.0 82.4 122.2 383.8 226.5 67.8 128.9 167.0 370.7 189.5 203.6 150.0 282.0 52.0 138.8 560.4 55.5 490.8 74.8 104.3 217.3 549.8 315.5 49.7 151.9 394.4 616.9 27.4 273.2 204.0 203.7 46.1 1069.6 79.2 61.9 660.7 64.9 32.6 270.7 195.9 17.5 106.4 172.2 120.5 63.4 71.6 49.7 87.2 5.5 8.7 275.9 55.3 286.2 30.8 3.0 39.5 0.7 31.5 36.0 161.5 92.0 114.3 67.4 33.5 71.4 195.2 128.0 4.1 85.5 26.9 1.4 95.6 88.9 2.6 2.2 3.7 3.3 2.3 6.3 9.2 5.0 6.0 4.5 5.5 4.4 218.0 57.7 70.4 0.7 108.0 1013.3 1080.5 278.9 1270.8 0.6 251.3 207.3 10.9 44.3 98.4 12.9 0.0 20.6 20.9 23.0 1.9 78.3 1.0 43.9 224.5 158.0 12.5 189.1 1.6 43.6 61.2 337.9 46.4 72.0 57.0 47.6 141.0 25.8 26.9 0.0 1.1 67.8 97.6 43.7 133.1 3.9 98.8 23.3 168.9 1.0 17.0 1.4 5.2 0.0 0.2 66.5 40.4 67.4 45.7 364.8 4.8 13.3 21.5 0.3 46.0 458.5 349.1 0.6 0.6 768.8 1070.1 5.9 75.0 56.0 117.7 409.4 NBPF26 ENSG00000273136 "NBPF member 26" 1 120723949-120842110 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 54.5;B-cells: 36.4;Basal squamous epithelial cells: 37.0;Erythroid cells: 55.5;Macrophages: 54.4;Squamous epithelial cells: 106.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.3" "Group enriched" "Detected in all" 5 "granulocytes: 13.3;monocytes: 7.3" "Low cell line specificity" "Detected in many" "HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved Microtubules,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol Microtubules "HPA038748: AB_2676188, HPA038752: , HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (2.42e-1)" "unprognostic (2.11e-1)" "unprognostic (2.24e-1)" "unprognostic (7.64e-3)" "unprognostic (4.21e-1)" "unprognostic (1.34e-3)" "unprognostic (1.69e-1)" "unprognostic (1.26e-2)" "unprognostic (6.31e-5)" "unprognostic (9.78e-3)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" "unprognostic (2.82e-5)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (8.11e-2)" "unprognostic (1.65e-1)" 14.7 7.2 5.4 21.9 5.1 13.2 11.0 7.6 6.3 14.9 13.7 10.2 2.5 15.1 20.1 20.7 11.2 13.3 6.5 3.8 5.8 4.9 10.4 13.3 12.5 5.4 4.4 17.0 8.9 4.3 4.7 8.5 3.6 12.6 9.3 23.1 10.2 8.9 6.4 39.0 8.6 17.3 2.0 13.9 7.5 10.3 8.0 11.9 12.2 5.4 8.5 7.9 11.5 5.8 56.7 0.3 16.4 17.8 18.3 16.9 1.3 19.9 10.1 12.5 12.9 12.2 2.3 4.4 17.2 17.5 21.6 14.4 27.8 28.7 17.4 25.1 1.3 40.1 7.5 4.8 9.1 16.0 11.4 10.2 11.8 31.1 32.6 40.5 0.8 10.5 3.0 30.1 29.5 28.7 4.2 24.6 6.3 2.0 21.5 5.5 15.3 8.2 7.3 19.9 1.5 1.3 22.1 30.5 16.6 19.5 1.0 6.7 17.3 14.0 36.3 43.7 15.7 13.5 4.1 16.2 11.6 23.5 2.2 2.4 5.1 4.6 1.4 2.3 0.7 0.8 1.0 1.2 1.4 2.0 1.0 1.5 13.3 1.3 7.3 1.3 0.5 0.7 5.4 5.1 7.6 6.3 3.8 5.8 5.4 4.4 3.6 2.0 8.0 5.8 0.8 54.5 28.7 3.9 36.4 0.0 2.2 0.0 37.0 0.6 3.9 2.4 2.7 0.0 3.7 0.0 0.0 0.5 4.7 0.6 3.9 4.8 7.6 7.2 4.8 1.4 0.0 55.5 0.4 3.1 2.4 14.9 16.3 7.8 16.4 2.5 1.1 1.4 0.2 0.0 0.3 1.0 0.0 4.4 0.0 0.9 6.5 54.4 0.0 1.0 6.5 0.6 2.1 0.5 0.1 4.0 27.3 4.5 28.0 1.0 1.7 0.7 3.6 2.1 0.0 3.1 6.7 4.9 2.5 106.5 0.0 0.4 21.1 0.9 2.2 0.8 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 325.5" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 95.5;Suprabasal keratinocytes: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.5;T-cells: 18.5" "Cell line enhanced" "Detected in all" "Karpas-707: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 72.3 53.7 23.5 6.3 27.0 5.4 63.1 52.9 49.7 109.6 10.6 53.3 14.3 35.8 4.5 42.5 27.7 7.1 60.8 24.9 17.2 38.0 43.2 49.2 9.3 18.1 20.9 71.3 24.3 9.0 32.0 6.0 15.9 40.5 4.0 50.4 52.9 16.3 99.0 325.5 23.0 7.5 12.9 11.6 31.5 12.5 34.0 6.3 32.1 38.1 5.4 42.5 96.5 25.2 5.5 7.8 1.6 6.2 9.0 6.2 2.2 11.9 19.5 3.9 4.9 5.1 19.5 6.7 6.9 13.8 12.9 15.4 4.1 18.0 2.9 5.6 4.1 4.8 7.9 13.5 14.6 7.2 6.9 13.5 12.8 13.3 28.2 12.6 4.9 7.7 7.2 60.6 3.8 3.8 10.7 6.1 3.0 10.8 12.3 7.5 2.2 20.7 5.4 4.9 5.1 2.9 7.6 9.7 12.4 2.7 4.6 5.8 4.7 17.2 16.7 14.1 9.5 21.5 35.7 2.6 23.4 4.0 13.6 0.0 0.5 0.0 4.4 2.0 18.5 1.7 5.5 6.4 1.1 2.1 4.8 3.5 0.2 1.0 5.5 1.4 8.0 1.8 23.5 27.0 52.9 49.7 24.9 17.2 18.1 20.9 15.9 12.9 34.0 25.2 16.4 3.2 2.0 17.3 5.7 64.5 47.5 20.5 67.2 71.4 9.4 15.1 5.7 8.6 11.9 1.8 4.2 2.6 4.9 26.0 7.9 16.1 2.3 25.4 30.6 18.6 8.3 3.6 7.1 11.8 1.2 26.5 31.1 64.2 2.5 2.7 6.8 31.8 2.5 42.1 6.2 7.2 8.2 3.4 19.4 1.5 21.8 7.7 19.6 8.4 1.2 39.0 5.2 5.0 1.2 26.0 14.7 38.7 10.5 35.4 58.8 7.9 5.0 29.7 6.6 9.6 19.4 2.0 11.1 95.5 81.1 2.3 11.9 13.7 6.0 28.7 NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.1;skeletal muscle: 17.1;skin 1: 31.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 35.6;Basal respiratory cells: 24.0;Basal squamous epithelial cells: 15.4;Breast myoepithelial cells: 24.3;Club cells: 9.5;Cytotrophoblasts: 13.6;Urothelial cells: 11.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 31.1;HBEC3-KT: 11.7;hTCEpi: 50.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA049376: AB_2680735" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" "unprognostic (9.27e-4)" "unprognostic (1.76e-4)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.87e-3)" "unprognostic (3.90e-4)" "unprognostic (2.97e-1)" "unprognostic (1.40e-3)" "unprognostic (3.71e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-2)" "unprognostic (2.46e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 4.3 0.7 0.0 0.0 0.1 3.7 10.8 2.5 0.0 1.0 0.1 0.0 0.1 0.0 3.5 0.0 0.1 0.2 0.2 0.0 0.0 1.6 3.2 0.1 20.1 0.0 0.0 8.2 7.1 17.1 31.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.9 1.5 2.5 1.1 6.5 9.6 0.1 3.9 0.2 0.3 2.1 0.0 0.0 9.3 0.0 0.0 0.1 0.0 3.4 13.8 0.0 3.5 0.0 0.5 31.1 0.1 11.7 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 50.4 0.0 1.6 3.1 0.0 0.1 0.0 0.2 0.4 1.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 8.8 0.0 0.1 0.7 0.1 0.0 4.3 8.0 0.1 0.2 1.8 3.5 0.2 9.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 3.2 0.0 0.0 0.0 7.0 35.6 24.0 15.4 0.0 3.4 24.3 0.4 0.0 9.5 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 5.7 0.0 0.0 0.0 0.9 0.0 1.3 1.7 3.1 2.7 0.3 0.1 0.0 11.9 PARD3 "ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118" ENSG00000148498 "Par-3 family cell polarity regulator" Q8TEW0 10 34109560-34815325 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 455.4;Inhibitory neurons: 147.0;Microglial cells: 193.0;Oligodendrocyte precursor cells: 367.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 50 "basophil: 9.6" "Lineage enriched" "Detected in single" 97 "granulocytes: 9.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030443 Approved Supported "Plasma membrane,Cell Junctions" NA NA 21000 "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cell Junctions" "HPA030443: AB_10600926" "unprognostic (9.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.62e-1)" "unprognostic (2.83e-2)" "unprognostic (1.81e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (3.48e-1)" "unprognostic (3.49e-1)" "unprognostic (8.07e-2)" "unprognostic (5.82e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.54e-1)" "unprognostic (9.20e-2)" "prognostic unfavorable (4.41e-4)" 13.1 15.9 19.6 4.8 17.0 0.5 21.5 10.9 12.4 25.9 16.0 30.4 10.6 20.7 12.2 47.8 20.6 14.9 14.6 17.8 20.6 25.1 22.1 15.2 2.6 15.7 22.1 38.5 34.2 20.7 7.3 21.7 15.9 17.0 21.7 13.6 20.1 23.9 40.5 52.1 13.4 21.8 16.0 4.2 17.7 14.0 24.0 13.5 15.2 30.9 12.4 21.3 30.8 13.9 50.6 121.1 40.1 28.6 28.5 24.2 59.1 22.2 25.4 37.3 40.0 44.3 43.3 0.3 31.4 44.6 30.4 35.8 34.7 56.7 46.1 0.4 26.8 0.0 14.9 44.1 36.2 5.7 0.1 28.7 54.9 50.9 38.1 35.9 23.3 32.4 34.7 14.9 44.8 35.4 59.3 4.2 18.0 32.7 41.4 44.9 39.0 21.9 80.9 38.4 20.1 20.9 26.8 37.3 42.9 49.6 21.1 6.7 28.4 18.7 56.1 35.5 24.2 13.2 17.1 0.1 21.0 0.2 22.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 19.6 17.0 10.9 12.4 17.8 20.6 15.7 22.1 15.9 16.0 24.0 13.9 6.4 35.3 35.3 455.4 0.2 34.0 42.3 19.8 19.9 8.7 17.1 24.9 39.0 21.5 24.3 14.7 29.2 24.9 0.2 25.6 0.0 34.1 19.9 22.3 29.9 9.4 24.0 2.7 5.4 36.4 25.0 22.3 13.3 33.4 1.3 33.1 8.9 24.8 3.4 11.8 147.0 30.1 14.2 0.6 4.7 20.3 30.4 7.7 5.4 193.0 0.8 28.8 1.0 367.9 13.9 38.8 23.8 38.4 1.4 31.4 13.7 25.6 29.3 19.7 26.3 23.4 26.1 6.2 27.6 40.4 61.5 40.1 1.5 32.1 22.0 47.2 PARD6G "PAR-6G, PAR6gamma" ENSG00000178184 "Par-6 family cell polarity regulator gamma" Q9BYG4 18 80157232-80247514 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.6;Oligodendrocyte precursor cells: 25.6;Squamous epithelial cells: 25.3;Suprabasal keratinocytes: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 36.4;hTCEpi: 34.0;RT4: 27.9;U-2 OS: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047017 Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA047017: AB_2679904" "unprognostic (1.11e-1)" "unprognostic (4.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.40e-2)" "unprognostic (2.97e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.80e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.09e-2)" "unprognostic (6.86e-3)" "unprognostic (9.65e-2)" "unprognostic (1.01e-1)" "unprognostic (4.85e-1)" "unprognostic (2.72e-1)" 3.4 1.7 5.8 1.4 5.7 0.6 5.3 3.8 7.9 9.6 6.8 6.0 1.8 6.5 2.7 18.0 6.2 3.3 2.9 9.3 7.8 7.0 3.5 2.9 2.5 6.3 5.8 6.2 2.1 2.1 3.8 5.5 5.5 5.7 2.0 1.8 4.5 5.9 1.9 38.1 3.0 5.4 4.6 2.0 2.7 2.1 8.3 5.3 18.0 1.0 4.3 5.6 12.0 5.9 3.0 4.3 17.7 13.4 0.6 0.7 12.9 3.3 0.7 2.9 0.4 1.2 1.2 0.0 1.4 1.5 5.1 13.4 6.4 19.2 2.8 0.5 5.7 0.2 3.5 10.4 0.8 4.0 36.4 5.7 34.0 0.3 1.8 2.2 1.4 4.2 1.4 0.8 4.3 5.0 3.6 0.4 5.3 1.4 5.2 0.1 11.7 1.5 0.5 27.9 7.4 7.7 4.1 2.2 20.0 8.6 2.6 3.4 1.1 5.9 28.8 2.2 1.6 0.9 1.2 0.3 1.9 0.9 11.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 5.7 3.8 7.9 9.3 7.8 6.3 5.8 5.5 4.6 8.3 5.9 3.3 3.2 0.6 7.5 0.7 39.6 13.7 11.0 18.8 1.3 4.1 10.3 2.8 1.5 2.3 3.7 0.0 0.6 9.7 0.4 0.0 0.4 0.5 9.8 10.1 8.2 0.0 0.0 6.5 0.2 9.5 4.1 0.5 3.3 0.0 3.1 10.8 1.5 0.8 0.0 8.5 0.7 8.2 0.9 6.5 0.7 1.8 0.8 12.4 15.9 0.0 2.0 0.0 25.6 4.8 0.8 0.0 1.9 3.6 6.6 0.0 7.6 2.6 2.5 19.7 1.9 13.6 1.5 6.0 25.3 63.9 0.4 8.0 2.0 0.6 13.4 PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 38.9;skin 1: 73.7;vagina: 21.4" "Cell type enriched" "Detected in single" 12 "Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;head and neck cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "HaCaT: 3.8;HDLM-2: 1.6;hTCEpi: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 73.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 7.6 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.5;esophagus: 8.2;skin 1: 15.1;vagina: 10.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 30.1;Club cells: 9.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.7;HDLM-2: 2.2;Karpas-707: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 2.3 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 30.1 0.6 0.0 0.0 0.1 0.3 0.0 9.7 0.0 0.0 0.0 0.0 0.1 0.0 1.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 0.3 0.3 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 4.0 3.4 0.3 0.0 0.0 0.2 0.2 PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 416.7;skin 1: 699.9;vagina: 200.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 139.7;Squamous epithelial cells: 234.5;Suprabasal keratinocytes: 409.0" "Group enriched" "Detected in many" 4 "cervical cancer: 125.5;head and neck cancer: 295.4;lung cancer: 79.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 234.6;HBEC3-KT: 144.2;hTCEpi: 501.4;hTERT-HME1: 132.5;PC-3: 192.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2500000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "CAB033130: AB_2164139, HPA027221: AB_10599737" "unprognostic (3.55e-3)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.49e-1)" "unprognostic (5.02e-2)" "unprognostic (2.20e-3)" "unprognostic (2.67e-1)" "unprognostic (9.17e-3)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-3)" 9.7 0.2 0.3 0.2 0.2 0.2 31.7 0.0 1.1 102.9 0.0 0.4 0.2 0.2 3.3 416.7 1.0 0.1 0.6 0.2 0.0 0.4 0.3 5.0 0.2 0.0 1.1 0.2 0.5 0.0 0.6 5.5 0.5 32.3 0.2 32.4 60.5 9.1 6.6 699.9 0.6 0.0 0.0 0.1 0.4 0.2 0.0 23.7 0.5 2.9 48.0 3.2 200.4 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 1.1 0.0 0.2 0.1 0.0 234.6 0.0 144.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 501.4 5.6 132.5 0.0 0.0 0.1 0.0 0.2 0.0 38.4 0.0 0.1 0.0 0.0 192.6 0.0 0.4 0.0 0.0 1.1 0.0 0.0 18.3 4.4 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 1.1 0.2 0.0 0.0 1.1 0.5 0.0 0.0 0.0 39.9 0.0 0.0 0.3 0.0 139.7 58.2 57.1 63.7 34.7 7.7 17.9 1.9 0.0 20.0 0.0 2.1 0.1 0.1 0.1 0.0 2.5 0.1 0.2 0.1 4.1 0.0 0.0 0.6 1.1 0.1 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.0 0.1 1.6 4.1 0.0 16.5 0.8 0.0 0.4 16.0 0.0 0.0 5.2 0.0 0.0 0.1 16.1 0.1 0.0 0.0 25.7 0.2 0.1 2.8 37.4 0.0 6.1 2.0 0.0 0.1 234.5 409.0 0.1 1.1 0.0 0.1 47.5 PLA2G2F ENSG00000158786 "Phospholipase A2 group IIF" Q9BZM2 1 20139323-20150381 "Enzymes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Innate immunity, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 25 "lymphoid tissue: 8.0;skin 1: 14.9;urinary bladder: 11.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Collecting duct cells: 1.8;Suprabasal keratinocytes: 1.7" "Cancer enriched" "Detected in some" 18 "urothelial cancer: 17.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 69 "RT4: 139.2" "Region enriched" "Detected in single" 4 "hippocampal formation: 3.0" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.79e-2)" "unprognostic (5.11e-2)" "unprognostic (4.63e-2)" "unprognostic (4.83e-2)" "unprognostic (1.51e-1)" "unprognostic (1.61e-2)" "unprognostic (3.36e-5)" "unprognostic (7.06e-2)" "unprognostic (1.84e-1)" "unprognostic (4.69e-1)" "prognostic favorable (3.86e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 8.0 11.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.8 0.0 0.0 0.0 0.9 PLA2G4D cPLA2delta ENSG00000159337 "Phospholipase A2 group IVD" Q86XP0 15 42067009-42094562 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 19.1;skin 1: 16.1;vagina: 22.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Glandular and luminal cells: 1.1;Ionocytes: 2.0;Prostatic glandular cells: 3.0;Rod photoreceptor cells: 1.0;Suprabasal keratinocytes: 3.4" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 2.0;melanoma: 1.8;prostate cancer: 1.3;urothelial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "RPMI-8226: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA074206 Approved "Plasma membrane,Cytosol" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 35: Glandular cells - Unknown function" Cytosol "Plasma membrane" "HPA074206: " "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (2.91e-2)" "unprognostic (9.16e-3)" "unprognostic (9.33e-3)" "unprognostic (4.35e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-2)" "unprognostic (2.75e-1)" "unprognostic (2.64e-7)" "unprognostic (2.54e-2)" "unprognostic (2.34e-1)" "unprognostic (3.47e-2)" "unprognostic (4.32e-2)" 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.0 0.3 5.2 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.2 19.1 0.0 0.2 0.8 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.4 22.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 15.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.1 0.0 1.0 0.0 0.0 0.1 0.0 0.4 0.0 3.4 0.0 0.0 0.0 0.1 0.4 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 12.9;Basal keratinocytes: 18.1;Suprabasal keratinocytes: 44.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041105, HPA072562" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Cytosol" "HPA041105: AB_2677300, HPA072562: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 18.1 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 5.1 0.5 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 5.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 44.9 0.0 0.1 0.0 0.2 0.7 PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 78.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 74.5;Distal enterocytes: 21.7;Gastric mucus-secreting cells: 18.3;Glandular and luminal cells: 17.1;Suprabasal keratinocytes: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "OE19: 11.1;RT4: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: AB_2683226" "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" 0.0 0.0 0.1 0.4 0.3 0.3 2.4 0.1 0.1 5.7 0.0 6.4 6.7 0.0 1.6 5.7 0.1 0.1 0.3 0.1 0.0 7.8 0.2 12.2 0.1 0.0 0.0 0.0 0.1 2.9 1.7 0.1 0.0 4.3 3.8 0.2 2.6 0.4 2.9 78.1 4.2 0.1 0.0 0.1 2.4 0.1 0.0 4.4 1.9 0.5 0.3 1.2 11.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 11.1 0.1 0.0 0.0 0.0 0.0 8.3 0.4 0.0 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 74.5 0.0 0.0 5.5 2.7 1.3 0.6 0.0 1.2 0.3 2.9 0.0 0.5 5.5 0.0 1.7 0.0 21.7 3.9 0.4 0.0 7.3 1.0 0.1 0.0 0.0 0.0 1.3 0.7 0.1 18.3 17.1 2.5 0.0 0.0 0.0 0.1 0.0 0.0 7.7 4.1 0.0 0.3 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.3 0.0 0.3 3.1 10.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 5.6 13.8 1.2 0.6 0.0 6.7 2.0 PMEL "D12S53E, gp100, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "cervix: 80.5;endometrium 1: 32.2;skin 1: 115.2" "Cell type enriched" "Detected in many" 32 "Melanocytes: 1472.7" "Cancer enriched" "Detected in many" 500 "melanoma: 2481.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 68 "SK-MEL-30: 8590.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA 11000000 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: AB_2673976" "unprognostic (4.63e-1)" "unprognostic (8.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.60e-1)" "unprognostic (5.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-3)" "unprognostic (6.44e-2)" "unprognostic (1.21e-1)" "unprognostic (5.12e-2)" "unprognostic (3.98e-1)" "prognostic favorable (3.70e-4)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.04e-1)" 3.3 0.8 0.2 0.8 0.2 1.8 8.3 0.7 0.5 80.5 0.3 1.3 1.6 32.2 1.5 0.7 1.2 1.6 0.6 0.3 0.0 2.1 5.0 0.9 5.6 0.0 0.4 4.3 2.3 1.7 0.7 2.8 0.1 0.9 1.2 0.4 3.5 0.8 0.3 115.2 2.1 3.5 0.0 0.5 1.1 4.8 0.0 0.7 1.1 0.2 2.2 1.3 4.0 0.3 14.8 1.1 5.6 0.2 83.6 0.6 126.2 0.9 0.8 1.9 2.0 12.8 6.0 2.6 6.1 0.8 0.3 2.5 0.6 1.0 1.6 3.0 2.1 2.4 2.5 0.7 0.3 1.0 1.4 0.5 1.0 1.2 0.6 1.3 1.0 1.1 0.5 1.8 0.5 2.7 0.4 1.0 17.1 2.8 0.3 1.6 3.5 1.5 1.4 2.7 0.5 2.6 0.3 2.5 8590.9 4.6 4.4 8.8 1.4 0.9 6.5 0.7 7.9 2.1 10.4 3.2 1.0 2.7 0.3 0.0 0.3 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.7 0.5 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.1 45.9 0.8 1.1 2.8 0.0 1.0 0.9 0.4 1.5 2.2 0.0 0.0 12.1 0.0 1.5 0.0 2.1 8.0 0.7 0.2 1.2 0.0 0.8 0.1 2.3 12.4 1.6 1.1 0.5 0.0 11.1 0.0 2.9 1.7 0.0 0.1 1.6 0.0 0.3 14.6 5.3 12.2 0.6 1472.7 1.0 0.6 0.2 0.0 0.0 0.1 1.0 0.6 0.7 1.2 0.5 2.4 2.8 1.0 0.0 0.0 0.2 1.7 3.9 2.6 1.0 10.2 24.9 0.4 1.3 1.6 0.4 POF1B "FLJ22792, POF" ENSG00000124429 "POF1B actin binding protein" Q8WVV4 X 85277396-85379717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.2;skin 1: 123.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 129.8;Gastric mucus-secreting cells: 48.9;Intestinal goblet cells: 61.1;Paneth cells: 62.5;Proximal enterocytes: 73.6;Squamous epithelial cells: 39.2;Undifferentiated cells: 51.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 44.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory B-cell: 2.9;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Group enriched" "Detected in some" 5 "OE19: 179.0;RT4: 78.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002033, HPA050027" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 200000 "Cluster 19: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA002033: AB_1079650, HPA050027: " "unprognostic (2.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.54e-3)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.97e-1)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (1.86e-1)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (1.17e-2)" "unprognostic (2.50e-1)" "unprognostic (4.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.81e-1)" "unprognostic (5.57e-4)" "unprognostic (1.01e-2)" 0.7 0.3 0.1 6.1 0.1 0.2 11.0 0.8 0.3 6.4 0.0 54.2 34.4 0.2 0.5 33.1 6.2 9.0 10.6 0.1 0.0 1.4 0.4 1.8 0.5 0.0 0.0 0.1 6.9 0.0 0.3 1.0 0.0 2.9 50.9 0.4 8.5 1.3 0.8 123.9 43.4 2.0 0.0 3.5 23.7 0.2 0.0 0.5 0.5 0.0 12.0 14.3 14.7 0.0 3.7 22.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.5 23.9 12.0 3.3 0.0 0.1 23.7 5.1 0.4 0.0 2.4 0.1 4.4 0.1 0.1 0.0 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.3 0.7 3.9 0.0 9.6 0.1 0.2 0.0 179.0 0.0 0.2 1.0 0.1 0.0 78.2 0.1 0.1 0.0 6.0 0.0 1.8 2.4 1.0 0.2 0.1 0.1 0.2 0.3 2.0 4.8 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.7 1.2 9.1 4.9 7.9 12.0 0.0 2.5 0.8 24.2 8.6 10.2 5.5 0.0 3.2 0.0 129.8 0.0 13.8 0.0 0.3 0.0 1.7 22.8 0.0 0.4 15.6 0.6 3.4 48.9 0.2 0.0 0.0 0.4 0.2 0.3 0.0 0.4 61.1 6.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.4 24.8 62.5 0.0 0.2 3.9 73.6 0.1 9.5 0.0 0.0 0.1 0.9 0.0 0.1 39.2 28.6 5.3 0.3 0.0 51.1 17.1 POSTN "OSF-2, periostin, PN" ENSG00000133110 Periostin Q15063 13 37562583-37598844 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 207.2;stomach 1: 174.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 295.7;Breast myoepithelial cells: 158.1;Endothelial cells: 134.6;Fibroblasts: 191.5;Smooth muscle cells: 151.5" "Cancer enhanced" "Detected in all" "breast cancer: 231.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTEC/SVTERT24-B: 490.2;SuSa: 440.5;U-138 MG: 619.3;U-2197: 427.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 87.9" HPA012306 Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to extracellular matrix" NA NA 660000000 "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Nucleoplasm "HPA012306: AB_1854827" "unprognostic (7.73e-2)" "unprognostic (1.44e-3)" "unprognostic (2.19e-2)" "unprognostic (2.57e-2)" "unprognostic (4.73e-2)" "unprognostic (2.22e-2)" "unprognostic (4.19e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (3.05e-3)" "unprognostic (7.10e-2)" "unprognostic (1.32e-2)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.83e-7)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (8.32e-3)" 71.4 5.2 4.5 23.8 0.1 0.3 84.0 0.0 4.4 20.3 2.9 61.3 5.1 53.2 13.0 20.5 83.5 64.3 83.2 3.0 0.0 28.1 13.0 45.1 12.8 0.9 0.0 3.6 2.2 21.6 2.4 60.9 2.0 16.1 84.9 0.0 17.7 44.8 10.6 207.2 15.0 66.6 0.0 1.1 174.6 3.4 0.1 5.8 19.1 29.9 3.9 91.4 10.7 0.4 0.0 0.0 71.0 1.6 85.0 51.0 0.2 23.1 0.0 5.5 0.7 0.0 1.4 0.1 0.0 18.7 0.1 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.0 14.2 0.2 0.1 90.8 0.0 490.2 1.9 15.9 0.7 0.0 0.0 0.0 11.8 0.0 0.3 0.4 4.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.4 0.2 0.1 0.6 0.0 440.5 0.9 0.0 0.0 619.3 0.3 427.2 3.4 0.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.0 4.4 3.0 0.0 0.9 0.0 2.0 0.0 0.1 0.4 46.7 6.4 10.6 0.7 0.3 295.7 1.3 51.5 0.0 0.0 2.9 158.1 22.8 0.0 18.7 0.0 0.0 2.5 1.0 0.0 0.0 0.0 0.5 0.5 9.8 134.6 0.0 0.0 1.5 0.0 0.2 191.5 0.0 0.3 3.8 0.0 22.5 0.6 3.7 0.0 36.8 0.0 24.4 0.0 27.0 1.1 6.5 0.8 30.2 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.7 0.4 0.4 0.0 0.0 5.6 0.0 0.0 0.7 151.5 1.3 0.9 0.2 48.4 3.4 2.3 49.3 0.0 0.3 PPP1R13L "IASPP, RAI" ENSG00000104881 "Protein phosphatase 1 regulatory subunit 13 like" Q8WUF5 19 45379638-45406349 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 179.4;heart muscle: 139.4;skin 1: 219.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.6;Granulosa cells: 118.3;Syncytiotrophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBEC3-KT: 130.1;hTCEpi: 189.0;hTERT-HME1: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005016, HPA041231, HPA059883" Approved Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005016: AB_2168576, HPA041231: AB_2677376, HPA059883: AB_2684151" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" "unprognostic (7.46e-2)" "unprognostic (2.92e-1)" "unprognostic (3.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.31e-3)" "prognostic unfavorable (3.39e-5)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.40e-4)" "unprognostic (2.52e-3)" "unprognostic (1.92e-2)" "unprognostic (1.55e-3)" "unprognostic (1.34e-1)" "unprognostic (7.69e-2)" "unprognostic (8.87e-2)" "unprognostic (1.02e-1)" 20.4 20.1 11.7 2.9 11.7 0.6 29.6 11.5 14.0 44.9 9.5 11.1 5.0 8.2 15.2 179.4 9.6 6.0 139.4 10.8 14.3 24.8 12.6 20.3 2.6 11.9 11.1 8.8 31.5 12.2 11.8 26.6 11.7 30.8 6.8 13.6 55.6 13.3 5.8 219.8 9.1 5.4 10.0 6.4 12.0 3.1 12.7 4.0 17.7 4.4 18.8 23.6 84.9 12.4 72.3 10.7 4.6 3.8 4.7 2.9 61.5 14.5 2.5 17.5 24.3 23.1 70.6 9.5 5.9 11.9 36.5 97.2 4.0 130.1 16.0 24.0 5.9 1.4 36.3 8.7 10.0 1.0 3.4 4.0 189.0 27.9 131.9 79.2 33.2 7.9 8.1 3.6 1.2 64.7 1.8 1.9 5.3 36.9 18.3 7.4 5.6 1.7 22.9 95.0 2.4 7.6 64.5 68.4 1.6 30.0 58.2 1.9 46.3 23.1 60.9 1.8 76.2 35.1 42.1 6.5 3.3 2.9 5.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.0 11.7 11.7 11.5 14.0 10.8 14.3 11.9 11.1 11.7 10.0 12.7 12.4 14.3 35.3 13.0 9.4 2.0 68.7 85.6 38.4 67.2 1.7 21.9 28.6 38.8 20.0 27.8 20.2 10.4 83.2 2.5 17.8 5.9 34.9 0.7 8.7 3.0 13.4 7.2 10.1 0.8 15.8 37.7 5.6 8.6 17.1 4.5 118.3 11.7 2.5 7.6 0.0 0.9 6.9 14.2 1.6 5.0 0.5 5.9 2.2 12.4 9.4 1.9 2.4 2.1 2.5 1.6 50.4 17.2 12.4 6.1 44.2 22.6 3.9 16.3 26.8 6.6 8.4 14.1 2.7 2.1 81.2 71.0 128.5 2.5 2.8 9.0 63.4 PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 75.5;skeletal muscle: 66.5;skin 1: 97.2;thyroid gland: 58.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 280.2;Cardiomyocytes: 79.5;Skeletal myocytes: 80.9;Suprabasal keratinocytes: 336.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 40.7;HBEC3-KT: 86.1;HEK 293: 36.2;hTCEpi: 103.0;hTERT-HME1: 41.1;RPTEC TERT1: 35.5;SK-BR-3: 37.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB044667: , HPA047907: " "unprognostic (1.81e-3)" "unprognostic (7.65e-2)" "unprognostic (4.25e-3)" "unprognostic (6.92e-2)" "unprognostic (3.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.81e-3)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (5.13e-2)" "unprognostic (4.50e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (7.49e-3)" "unprognostic (6.77e-2)" 0.4 0.2 5.1 1.4 6.6 0.2 6.0 5.9 8.0 10.2 6.0 12.5 10.4 1.4 0.9 18.4 16.0 0.1 75.5 7.8 5.0 9.5 0.0 12.3 0.3 5.6 5.4 0.1 0.7 5.1 1.7 3.4 5.6 1.3 8.6 0.6 3.2 0.2 66.5 97.2 2.7 0.9 4.4 0.1 0.8 6.7 5.0 0.5 58.7 8.5 5.8 0.5 22.0 5.0 27.9 0.1 11.7 0.1 0.1 0.6 0.0 3.7 0.0 0.0 0.1 1.3 3.8 0.7 8.0 5.3 1.8 40.7 6.1 86.1 0.0 0.0 36.2 0.3 0.0 0.0 0.0 0.0 1.1 0.0 103.0 0.2 41.1 0.0 0.0 0.5 23.6 0.0 0.0 3.8 0.0 0.0 0.4 0.0 0.2 0.7 0.0 0.0 35.5 1.5 6.2 0.0 0.6 37.7 2.2 0.7 0.2 1.9 0.0 0.1 20.4 32.5 9.5 0.0 0.0 0.0 14.2 16.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.6 5.9 8.0 7.8 5.0 5.6 5.4 5.6 4.4 5.0 5.0 0.3 19.2 41.1 1.3 0.5 280.2 17.9 19.6 12.0 1.1 6.5 4.3 79.5 0.0 17.1 14.7 0.0 0.1 0.4 24.5 1.9 3.8 0.2 37.9 0.6 3.0 28.2 0.0 28.0 0.2 0.1 6.7 0.0 5.1 1.3 4.1 0.0 0.0 3.0 1.7 13.3 3.1 14.2 0.0 19.7 1.6 0.0 0.6 30.2 2.8 1.1 0.0 0.0 37.2 2.5 12.8 41.5 0.4 0.0 16.6 5.0 38.6 61.5 0.5 0.0 80.9 4.3 0.5 1.8 14.7 336.6 1.9 1.4 0.5 8.7 1.9 PRRX2 "PMX2, PRX2" ENSG00000167157 "Paired related homeobox 2" Q99811 9 129665647-129722674 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.3;skin 1: 25.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.4;Early spermatids: 78.7;Fibroblasts: 44.2;Langerhans cells: 28.0;Smooth muscle cells: 21.2;Suprabasal keratinocytes: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 12.9;BJ: 28.7;BJ hTERT+: 20.3;fHDF/TERT166: 41.6;U-2197: 34.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.3" "HPA006607, HPA026808" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA006607: AB_2667623, HPA026808: AB_10603228" "unprognostic (4.02e-2)" "unprognostic (5.17e-2)" "unprognostic (7.65e-3)" "unprognostic (4.47e-3)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (2.16e-2)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.22e-1)" "unprognostic (1.94e-10)" "unprognostic (6.66e-2)" "unprognostic (4.48e-1)" "unprognostic (2.65e-2)" "unprognostic (9.47e-3)" 14.2 2.4 0.5 1.2 0.5 0.0 11.7 0.4 0.7 23.3 1.0 2.2 0.2 3.9 0.2 5.4 3.4 1.3 9.5 0.6 1.2 1.2 0.1 4.6 1.1 0.5 0.5 1.3 0.9 0.5 4.5 1.4 0.6 14.1 0.3 0.0 7.5 2.7 1.6 25.5 1.6 0.6 0.4 0.1 2.8 10.7 0.5 0.3 9.5 0.6 0.8 10.7 18.3 0.5 0.0 0.7 0.0 1.1 3.3 12.9 0.1 28.7 20.3 3.6 4.0 0.0 0.0 0.0 10.2 41.6 1.5 0.3 0.8 0.0 0.3 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 1.1 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.6 0.0 0.0 4.4 2.1 6.4 0.0 0.0 0.0 0.9 0.0 0.0 2.7 1.3 0.1 0.0 1.4 2.7 0.5 0.0 0.0 8.3 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.7 0.6 1.2 0.5 0.5 0.6 0.4 0.5 0.5 3.9 0.0 0.0 0.7 0.1 27.4 1.1 16.0 0.6 0.0 6.0 6.0 0.3 0.0 10.1 0.0 0.0 0.2 0.1 0.0 1.9 0.1 78.7 1.0 6.3 3.0 0.0 0.0 0.4 0.0 0.4 44.2 0.5 1.8 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 2.0 0.0 28.0 10.2 2.8 0.3 8.8 0.0 0.0 0.0 0.0 5.0 0.1 0.9 0.0 3.4 0.0 4.0 0.0 0.1 7.9 0.0 0.0 0.4 21.2 3.6 6.8 0.5 29.7 0.4 0.8 0.0 0.0 6.2 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.9" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1" "Cell line enhanced" "Detected in many" "ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" 12.8 2.9 3.1 10.5 3.2 9.0 6.7 4.2 4.8 5.8 5.5 108.3 10.8 6.1 2.2 67.3 43.2 9.6 12.6 7.4 5.5 9.3 3.0 11.3 4.6 6.5 5.2 2.0 1.8 2.0 4.8 2.2 6.3 21.1 24.2 0.7 4.3 6.1 2.1 152.5 17.7 16.1 6.7 8.0 20.5 0.9 7.0 2.2 3.2 4.0 11.6 175.0 15.9 11.9 0.3 0.5 0.4 0.0 113.7 89.5 0.0 115.2 156.0 1.0 1.1 0.0 0.2 4.2 5.4 19.7 0.3 7.1 0.4 10.5 0.9 0.0 0.2 73.6 0.6 0.0 32.9 5.2 298.4 46.1 1.2 5.7 0.3 0.0 42.3 0.1 0.1 0.3 2.3 0.0 0.2 6.6 1.6 0.0 0.5 0.3 1.4 8.6 14.7 0.0 0.5 0.6 0.6 9.5 0.2 0.5 0.3 8.4 1.0 0.7 0.6 1.7 0.1 0.3 0.2 0.0 0.4 31.6 0.3 28.9 12.1 23.3 0.0 13.1 0.0 2.4 0.0 0.0 20.0 3.5 0.1 0.0 5.2 2.8 10.2 1.4 0.2 21.9 3.1 3.2 4.2 4.8 7.4 5.5 6.5 5.2 6.3 6.7 7.0 11.9 0.9 0.0 6.6 0.0 5.9 9.9 2.6 7.7 0.0 0.1 1.1 1.4 1.6 4.3 2.2 42.3 0.0 0.1 0.2 0.1 0.0 0.6 0.1 109.9 10.4 24.7 1.8 18.7 0.8 0.5 0.3 10.7 2.0 191.9 208.0 0.1 61.8 0.8 26.1 0.0 0.5 0.6 4.1 15.5 20.7 0.3 1.5 55.3 3.6 16.9 11.7 0.0 7.2 1.0 0.1 0.6 0.6 0.0 0.3 2.8 0.0 0.0 0.8 0.1 0.0 1.4 3.6 0.0 0.2 18.2 58.7 0.4 3.4 0.1 1.0 0.8 PYCARD "ASC, CARD5, TMS-1" ENSG00000103490 "PYD and CARD domain containing" Q9ULZ3 16 31201486-31203450 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 84.7;skin 1: 90.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 425.8;Kupffer cells: 555.8;Macrophages: 344.2;Paneth cells: 360.0;Proximal enterocytes: 504.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 585.7;classical monocyte: 1098.3;eosinophil: 948.1;intermediate monocyte: 1138.3;myeloid DC: 829.2;neutrophil: 1638.4;non-classical monocyte: 1152.8;plasmacytoid DC: 769.2" "Group enriched" "Detected in all" 6 "dendritic cells: 829.2;granulocytes: 1638.4;monocytes: 1152.8" "Cell line enhanced" "Detected in many" "MCF7: 148.9;NB-4: 237.0;THP-1: 186.9;U-937: 112.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006853, CAB015948, HPA049074, HPA054496" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA 640000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Cytosol" "CAB006853: , CAB015948: , HPA049074: AB_2680621, HPA054496: AB_2682506" "unprognostic (1.00e-3)" "unprognostic (2.62e-2)" "unprognostic (2.40e-1)" "unprognostic (4.67e-3)" "unprognostic (3.34e-1)" "unprognostic (1.87e-1)" "unprognostic (5.29e-2)" "unprognostic (2.88e-2)" "unprognostic (3.12e-1)" "unprognostic (2.33e-1)" "unprognostic (6.52e-3)" "unprognostic (3.88e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (4.45e-3)" "unprognostic (2.51e-1)" "unprognostic (3.61e-2)" "unprognostic (6.97e-2)" 25.6 11.4 4.1 32.9 4.0 43.4 20.4 4.6 8.6 22.1 5.0 48.1 63.9 10.7 0.0 56.1 17.4 4.9 9.7 3.7 5.2 10.9 10.4 32.8 19.1 7.8 5.1 14.9 11.3 1.7 7.7 6.1 6.7 19.9 9.5 0.1 24.6 8.7 3.4 90.5 48.5 5.8 7.6 84.7 22.1 2.3 6.7 9.5 9.1 1.2 12.7 19.8 33.1 11.3 23.9 54.8 0.5 0.2 9.2 18.9 0.6 12.6 22.6 8.8 6.5 0.1 31.7 10.6 0.1 17.6 0.0 69.7 2.9 57.4 0.3 73.0 0.0 9.3 7.9 18.3 25.6 86.9 65.7 24.7 30.3 4.0 1.2 0.2 18.4 0.1 42.9 17.5 2.9 148.9 0.2 237.0 15.7 13.2 0.1 75.5 0.0 35.2 1.3 22.3 0.7 0.2 10.4 0.0 12.4 0.3 15.5 186.9 11.8 0.4 0.7 9.9 0.3 0.6 0.1 0.2 6.4 112.1 0.1 585.7 1098.3 948.1 178.4 1138.3 112.2 213.7 146.5 183.3 829.2 210.7 102.1 139.6 1638.4 219.2 1152.8 769.2 206.4 814.2 4.1 4.0 4.6 8.6 3.7 5.2 7.8 5.1 6.7 7.6 6.7 11.3 35.7 22.4 28.9 0.0 58.5 74.1 66.3 237.0 100.7 0.2 92.2 131.7 2.5 41.5 84.3 25.8 0.0 62.5 158.8 184.5 5.9 90.5 0.8 18.6 16.8 39.2 58.9 42.9 0.1 56.5 11.3 39.3 50.4 7.3 110.9 60.2 48.9 3.3 425.8 0.0 0.1 144.6 75.3 555.8 280.2 2.9 47.2 344.2 97.8 13.1 277.8 0.0 132.8 0.0 0.1 60.4 360.0 22.6 54.1 22.6 504.8 3.6 88.2 0.7 26.3 10.5 28.5 0.3 1.4 83.9 163.7 17.8 70.8 119.9 287.1 70.6 RAB7B "MGC16212, MGC9726" ENSG00000276600 "RAB7B, member RAS oncogene family" Q96AH8 1 205976740-206003461 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 52.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 13.6;Cytotrophoblasts: 29.0;Fibroblasts: 13.6;Hofbauer cells: 32.8;Squamous epithelial cells: 12.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "myeloid DC: 5.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 5.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 26.3;HBEC3-KT: 33.6;HL-60: 22.0;HMC-1: 89.1;hTCEpi: 38.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (4.18e-2)" "unprognostic (2.14e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (1.79e-2)" "unprognostic (7.88e-2)" "unprognostic (9.14e-2)" "unprognostic (2.23e-3)" "unprognostic (5.97e-2)" "unprognostic (8.57e-2)" "unprognostic (3.89e-3)" "unprognostic (3.13e-2)" "unprognostic (8.19e-2)" "unprognostic (1.63e-2)" "unprognostic (8.82e-3)" 8.0 0.9 1.7 5.2 3.2 1.3 11.0 3.5 2.5 8.5 1.6 2.7 2.8 6.9 5.9 20.2 5.6 15.0 5.1 1.6 2.2 0.6 2.4 8.8 8.5 4.3 3.5 3.5 1.3 0.6 1.8 7.1 3.0 5.8 3.1 0.8 7.2 7.5 2.1 52.1 2.5 8.0 4.1 3.8 7.0 1.1 5.7 6.7 8.1 2.2 4.9 8.2 15.5 7.0 1.5 0.1 0.7 0.8 1.9 14.5 3.5 6.8 8.1 2.8 2.6 0.9 2.4 0.0 2.3 26.3 2.9 6.6 0.0 33.6 0.9 0.3 0.0 0.0 0.0 0.8 0.1 22.0 89.1 4.9 38.2 5.2 0.1 1.7 0.1 0.0 0.4 0.0 1.9 0.4 0.1 13.3 0.3 1.1 0.0 0.0 1.9 0.7 0.8 0.3 0.0 0.1 0.9 0.0 4.4 6.9 2.3 7.5 0.0 1.9 4.5 1.8 0.5 0.1 0.0 0.0 12.0 9.3 3.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 1.7 3.2 3.5 2.5 1.6 2.2 4.3 3.5 3.0 4.1 5.7 7.0 0.8 3.2 3.9 1.3 0.2 0.0 8.3 0.0 13.6 0.0 1.9 5.5 0.7 4.3 6.2 0.0 0.0 29.0 0.1 0.0 0.0 3.6 0.0 0.8 7.9 0.7 0.0 0.0 1.7 0.2 1.0 13.6 3.6 0.6 2.5 0.4 0.7 0.1 32.8 0.0 0.1 0.0 0.0 6.4 0.0 0.8 1.8 11.0 0.0 1.9 4.1 3.1 0.0 0.0 8.2 0.6 0.1 3.4 0.1 0.7 0.0 0.0 0.0 0.4 0.0 3.2 2.8 0.0 0.1 12.6 0.0 6.3 0.8 0.1 0.0 1.9 RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 209.7;Urothelial cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 60.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" 4.5 4.8 2.5 3.4 2.6 2.2 4.5 3.9 3.6 9.4 3.9 8.6 6.7 4.2 0.7 19.8 4.8 3.0 13.0 2.4 3.5 9.2 8.2 4.4 3.5 3.5 4.2 3.7 8.6 12.4 6.4 10.1 3.7 6.3 3.8 2.1 9.6 3.7 9.7 21.0 6.1 2.0 1.6 6.2 10.5 5.3 3.8 2.2 7.5 4.8 2.7 5.1 12.2 2.3 10.9 12.3 2.9 10.3 1.5 3.0 17.9 3.4 2.1 3.7 6.4 23.3 15.7 9.4 5.3 1.2 2.7 14.1 7.8 7.2 1.7 7.3 60.0 12.2 9.8 14.6 2.9 12.4 8.0 2.6 6.3 3.0 2.9 3.7 3.0 5.2 27.2 2.9 2.3 13.4 6.1 9.6 2.5 17.7 25.7 15.7 6.7 27.6 8.2 37.3 8.8 6.2 8.9 31.3 7.0 2.7 12.0 9.3 3.0 0.3 3.7 0.1 8.2 7.8 11.0 9.6 9.1 10.6 6.6 3.8 4.1 4.1 8.2 6.3 7.7 5.4 6.3 7.6 4.2 5.8 8.4 6.1 1.9 7.8 5.0 6.4 5.5 3.0 2.5 2.6 3.9 3.6 2.4 3.5 3.5 4.2 3.7 1.6 3.8 2.3 8.9 16.0 13.1 3.9 6.6 10.7 31.7 11.1 7.4 21.0 12.2 9.9 27.5 20.0 19.3 14.7 41.7 41.3 9.4 47.2 11.7 13.5 24.3 18.3 8.8 9.1 12.0 4.2 9.4 6.5 29.0 7.1 46.4 31.8 8.2 24.4 18.5 7.3 11.5 25.2 10.0 27.5 12.2 4.9 5.0 13.2 3.7 4.2 7.2 4.7 5.0 9.0 6.2 5.0 2.9 14.5 35.7 3.4 8.7 30.6 20.3 4.8 12.8 25.3 6.6 5.1 6.5 3.2 8.9 11.1 17.5 209.7 9.2 11.1 28.1 110.1 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 63.3" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA021576: AB_1856331, HPA052404: AB_2681817" "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 20.9 12.9 11.1 13.5 12.5 11.6 18.6 11.2 14.2 16.0 15.1 17.5 13.6 13.3 16.5 22.4 15.7 9.6 8.5 10.4 11.3 21.6 8.6 15.5 13.9 13.9 13.2 12.6 13.5 16.8 5.6 18.1 12.4 14.0 18.0 2.3 15.2 15.2 7.4 26.2 13.9 13.7 12.8 25.8 11.9 5.1 16.4 7.9 15.8 10.1 12.6 14.8 17.3 13.8 12.7 25.6 1.5 25.4 34.0 28.5 22.7 9.7 14.9 9.4 8.4 0.0 9.4 11.5 14.8 19.0 17.0 17.0 13.2 12.1 7.8 10.0 5.6 4.8 8.1 0.0 24.3 12.8 10.7 27.7 63.3 10.1 33.5 16.1 15.8 0.0 0.0 34.9 15.6 17.0 0.1 13.5 10.5 25.7 14.4 27.9 0.0 39.2 13.6 18.2 9.8 0.5 14.9 5.9 14.9 16.6 39.4 20.2 13.3 0.0 3.5 15.6 11.5 0.4 1.3 7.3 16.5 22.1 13.3 25.3 61.6 31.3 12.8 57.3 7.2 28.4 6.8 6.8 46.4 28.4 3.7 6.2 54.0 13.9 70.2 17.1 10.1 29.2 11.1 12.5 11.2 14.2 10.4 11.3 13.9 13.2 12.4 12.8 16.4 13.8 14.1 3.2 5.9 7.8 14.1 9.3 13.4 16.8 22.2 0.1 13.1 15.0 4.0 7.2 7.8 11.0 0.0 47.5 10.5 23.4 29.4 9.9 0.4 14.5 12.8 13.2 4.9 11.2 0.8 18.6 37.1 13.2 5.6 12.4 1.3 14.1 25.4 2.7 51.1 0.0 1.0 12.0 8.2 73.9 8.4 1.6 16.8 35.5 16.0 26.2 45.3 3.9 19.6 9.0 0.7 11.9 13.1 15.4 9.0 22.2 27.5 49.3 10.4 0.6 26.3 8.2 14.2 0.7 4.0 24.1 14.6 43.6 7.5 10.6 14.6 11.2 RNF39 "FAP216, HZFw1, LIRF" ENSG00000204618 "Ring finger protein 39" Q9H2S5 6 30070266-30075887 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;skin 1: 63.3;vagina: 21.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 79.9;Basal respiratory cells: 96.2;Club cells: 55.7;Prostatic glandular cells: 57.2;Urothelial cells: 233.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 4.5;U-266/84: 3.6" "Region enhanced" "Detected in many" "cerebral cortex: 8.1" "Group enriched" "Detected in many" 4 "cerebellum: 9.0;cerebral cortex: 8.0;hippocampal formation: 4.4" "CAB019278, HPA047115" Uncertain Approved "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane, Centrosome" "CAB019278: , HPA047115: AB_2679938" "unprognostic (1.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.53e-2)" "unprognostic (5.72e-3)" "unprognostic (3.08e-2)" "unprognostic (4.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.22e-2)" "unprognostic (1.59e-2)" "unprognostic (4.45e-3)" "unprognostic (3.61e-2)" "unprognostic (2.06e-4)" "unprognostic (5.61e-2)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (2.57e-2)" 1.1 0.8 0.0 0.0 0.1 0.0 8.6 0.1 0.3 16.8 0.0 0.6 0.2 0.6 0.0 24.5 1.4 0.1 0.3 0.1 0.1 0.4 0.2 1.9 0.0 0.2 0.0 1.3 1.7 0.1 1.4 0.0 0.2 7.2 0.0 0.5 15.8 0.1 0.4 63.3 0.5 0.0 0.0 0.2 8.3 1.6 0.1 0.0 0.4 0.0 0.4 3.9 21.6 0.1 1.2 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.2 1.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.7 0.0 0.9 0.3 0.2 0.0 0.4 0.0 0.5 0.0 4.5 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.8 3.6 0.3 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.2 0.0 0.1 0.1 0.3 3.2 2.7 0.0 0.0 17.8 79.9 96.2 42.1 0.5 23.7 28.6 0.3 7.2 55.7 0.0 0.0 0.0 0.8 1.8 0.0 6.4 0.6 3.6 2.4 1.1 0.0 0.0 0.0 3.3 0.0 1.2 17.3 20.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 14.2 0.0 2.1 0.0 1.2 0.4 3.6 0.0 0.6 0.0 0.0 0.0 0.0 24.2 2.2 1.2 0.0 57.2 0.1 0.0 13.0 0.4 0.0 0.0 3.0 0.1 0.4 11.3 23.9 0.7 0.6 0.0 0.9 233.1 RNH1 "RAI, RNH" ENSG00000023191 "Ribonuclease/angiogenin inhibitor 1" P13489 11 494512-507300 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 262.3;monocytes: 299.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039223, HPA040781" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 22000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA039223: AB_10795581, HPA040781: AB_10796227" "unprognostic (1.87e-1)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.48e-3)" "unprognostic (6.09e-2)" "unprognostic (4.82e-3)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.44e-1)" "prognostic favorable (2.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.66e-1)" "unprognostic (4.78e-2)" "unprognostic (4.35e-2)" 163.5 137.2 27.3 29.0 41.8 46.3 133.7 42.4 33.9 156.4 28.9 123.0 27.1 140.8 10.0 215.0 119.5 29.7 198.0 26.3 32.5 118.6 111.9 146.7 30.8 48.6 39.7 119.1 89.5 25.6 80.6 27.3 38.2 100.9 8.8 5.6 112.5 31.0 145.9 257.4 91.1 25.3 35.3 113.3 101.1 90.1 38.3 15.6 106.6 21.8 13.9 144.5 160.3 49.4 86.5 123.9 13.2 39.8 66.3 93.8 43.9 70.6 51.3 68.9 58.3 61.9 92.9 41.8 54.3 175.1 41.9 72.7 20.6 76.5 10.4 51.3 104.9 28.2 28.5 65.7 243.3 39.8 90.0 77.1 108.2 40.2 46.7 29.2 47.9 27.7 36.2 71.3 37.7 86.6 30.5 78.4 19.8 45.3 112.6 37.7 22.3 55.8 40.7 34.6 35.7 23.2 41.8 59.1 73.7 7.4 44.6 122.2 77.3 109.3 32.8 39.8 49.5 44.9 53.0 32.2 117.5 81.9 74.3 37.6 246.2 57.3 51.1 298.9 59.9 63.0 55.3 51.1 262.3 48.4 49.8 45.1 17.1 54.2 299.1 71.7 58.4 236.5 27.3 41.8 42.4 33.9 26.3 32.5 48.6 39.7 38.2 35.3 38.3 49.4 156.0 112.2 83.5 18.9 92.3 202.1 239.0 265.0 89.4 102.4 82.0 105.5 83.3 88.6 138.6 79.1 110.5 222.2 85.3 126.6 225.0 188.8 105.1 72.8 132.4 136.1 57.4 59.7 10.9 164.4 217.4 194.9 64.2 82.8 140.2 93.8 101.7 68.6 374.0 168.2 14.5 115.6 148.5 191.8 323.0 42.7 211.6 230.3 193.9 12.2 334.2 144.6 79.3 10.1 70.8 171.6 120.5 179.8 101.7 161.0 139.4 242.3 97.9 146.4 177.5 99.1 178.0 153.4 157.8 140.0 260.0 305.5 96.5 199.7 114.4 217.4 RPTN FLJ39117 ENSG00000215853 Repetin Q6XPR3 1 152153595-152159228 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 52.2;skin 1: 29.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "head and neck cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030483, HPA030485" Enhanced "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA030483: AB_2673495, HPA030485: AB_10601159" "unprognostic (1.37e-2)" "unprognostic (5.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.54e-2)" "unprognostic (4.00e-2)" "unprognostic (5.23e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 29.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 52.2 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 RTL10 "BOP, C22orf29, FLJ21125" ENSG00000215012 "Retrotransposon Gag like 10" Q7L3V2 22 19846138-19854896 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Cytotrophoblasts: 20.6;Distal tubular cells: 13.7;Extravillous trophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 95.9" "HPA000721, HPA001419" Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" "HPA000721: AB_1079000, HPA001419: AB_1078999" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (3.70e-2)" "unprognostic (2.29e-2)" "unprognostic (4.72e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (8.04e-5)" "unprognostic (2.26e-2)" "unprognostic (2.36e-2)" "unprognostic (1.63e-2)" "unprognostic (1.38e-1)" "unprognostic (3.79e-2)" "unprognostic (6.67e-2)" "unprognostic (7.20e-3)" "unprognostic (3.34e-1)" "unprognostic (1.27e-1)" "unprognostic (7.55e-2)" 3.0 3.5 2.4 3.9 3.3 4.8 4.5 2.4 4.2 4.5 0.6 3.0 7.1 4.6 6.7 7.5 8.8 2.5 3.1 3.9 1.5 3.5 3.7 5.1 5.1 1.3 0.4 5.1 7.3 6.1 4.0 5.1 0.9 6.2 3.0 3.5 7.1 5.0 4.3 13.3 4.7 3.8 0.0 4.1 4.2 2.3 1.8 10.8 5.7 3.9 7.2 4.1 4.6 1.6 18.9 7.6 8.5 9.5 9.1 8.0 10.7 10.4 12.0 15.0 9.1 15.5 10.4 16.4 4.3 17.8 4.6 26.4 8.6 17.0 6.6 5.6 12.9 8.7 17.6 10.9 5.8 25.7 7.4 6.0 19.9 12.6 10.6 7.2 14.1 9.9 95.9 6.0 14.5 12.5 21.0 7.8 4.6 21.4 10.3 11.8 25.1 4.0 5.5 17.3 13.9 5.0 10.8 12.2 10.3 8.8 13.4 5.7 18.2 14.7 16.8 4.8 10.0 5.3 5.0 9.8 5.6 6.9 9.9 2.6 1.4 3.1 1.8 1.6 1.7 1.1 2.0 1.8 1.3 1.4 3.9 3.0 2.3 0.8 4.0 2.6 3.0 1.8 2.4 3.3 2.4 4.2 3.9 1.5 1.3 0.4 0.9 0.0 1.8 1.6 3.6 22.4 9.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 8.3 5.8 0.0 0.0 5.0 9.2 0.0 20.6 2.2 0.0 13.7 7.6 0.0 8.8 5.0 4.4 0.0 0.0 0.0 5.0 16.6 2.4 0.0 9.7 1.3 10.8 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 7.2 0.0 0.0 1.4 0.0 0.0 5.4 5.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 4.7 2.1 6.4 0.0 0.0 S100A3 S100E ENSG00000188015 "S100 calcium binding protein A3" P33764 1 153547329-153549258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 94.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.4;Ductal cells: 21.7;Endometrial stromal cells: 18.4;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 24.2;Skeletal myocytes: 24.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 26.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "intermediate monocyte: 3.1;non-classical monocyte: 6.2;plasmacytoid DC: 7.4" "Group enriched" "Detected in many" 11 "dendritic cells: 7.4;monocytes: 6.2" "Cell line enhanced" "Detected in many" "A549: 87.0;HBEC3-KT: 45.7;HeLa: 51.4;U-2197: 47.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 15.8" "HPA042674, HPA056140" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA 240000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Golgi apparatus, Plasma membrane" "HPA042674: AB_10796581, HPA056140: AB_2683050" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "unprognostic (3.59e-2)" "unprognostic (1.21e-2)" "unprognostic (4.53e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-1)" "unprognostic (2.08e-1)" "unprognostic (5.34e-3)" "unprognostic (3.97e-3)" "prognostic unfavorable (1.61e-6)" "unprognostic (8.13e-2)" "unprognostic (3.46e-1)" "unprognostic (6.21e-2)" "unprognostic (8.10e-2)" 7.6 1.1 0.9 3.6 1.1 1.8 4.2 0.8 1.3 6.9 0.6 2.8 0.5 3.9 0.2 17.2 3.3 1.7 2.6 0.8 1.4 13.8 0.2 16.6 1.8 1.4 1.6 1.1 0.8 0.1 0.7 2.2 1.2 3.0 1.1 0.0 4.2 1.7 1.0 94.6 1.9 2.1 1.1 0.8 1.4 0.5 2.8 0.4 1.5 1.9 5.1 6.9 9.6 1.4 7.3 87.0 0.1 0.1 8.1 5.2 0.0 6.1 31.4 7.9 12.8 2.6 2.8 0.1 19.0 16.1 10.7 22.2 0.1 45.7 3.7 0.3 0.0 0.3 51.4 15.3 2.2 0.0 0.3 4.1 24.9 17.9 19.9 4.5 1.7 0.0 0.0 0.0 39.8 0.5 0.0 0.0 0.6 0.2 11.5 0.0 5.9 4.7 26.0 18.3 1.2 0.0 5.4 6.1 2.0 24.7 0.2 0.6 8.6 2.9 4.8 47.4 6.3 1.4 1.6 0.2 38.2 0.7 19.1 0.0 0.1 0.0 0.0 3.1 0.2 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.2 7.4 0.1 0.4 0.9 1.1 0.8 1.3 0.8 1.4 1.4 1.6 1.2 1.1 2.8 1.4 2.0 3.2 0.5 0.7 0.0 10.3 2.3 15.4 4.0 0.0 0.3 0.4 0.3 1.5 5.9 0.0 0.0 0.3 0.0 0.0 1.9 21.7 0.0 2.3 18.4 7.4 0.0 1.3 0.0 24.0 4.4 8.4 0.0 1.3 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.1 0.1 4.1 0.4 1.8 0.0 3.6 0.0 0.0 0.0 0.0 24.2 0.0 0.4 0.0 1.5 0.0 0.3 1.1 0.0 0.0 24.7 9.6 0.1 0.0 5.6 6.5 1.5 0.5 1.1 0.0 2.0 SAPCD1 "C6orf26, NG23" ENSG00000228727 "Suppressor APC domain containing 1" Q5SSQ6 6 31762996-31764851 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.3" "Cell type enriched" "Detected in single" 15 "Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.4;U-2 OS: 1.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071699 Approved "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Cell Junctions" "HPA071699: AB_2686433" "unprognostic (9.25e-4)" "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (3.28e-1)" "unprognostic (9.34e-2)" "unprognostic (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (3.80e-2)" "unprognostic (2.01e-1)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "unprognostic (8.15e-10)" "unprognostic (2.65e-2)" "unprognostic (4.45e-1)" "unprognostic (3.57e-1)" "unprognostic (7.98e-5)" 2.7 1.1 0.4 0.0 0.4 0.2 2.5 0.5 0.9 2.4 0.4 3.7 0.0 2.5 0.1 2.5 3.9 0.0 1.2 0.4 0.3 7.4 3.1 2.0 0.6 0.4 0.5 3.8 2.1 0.0 6.1 0.1 0.4 6.0 0.2 1.2 2.3 0.1 1.0 28.3 3.9 0.1 0.4 4.8 2.6 3.6 0.4 0.2 2.2 0.0 0.1 2.5 2.2 0.4 0.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.3 0.2 0.0 0.1 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.7 0.4 0.2 0.2 0.2 0.5 0.0 0.1 0.7 1.4 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.7 0.1 0.4 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.4 0.3 0.4 0.5 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1056.2;skin 1: 2444.7;vagina: 756.5" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 1017.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.2;ASC TERT1: 107.5;HSkMC: 146.1;U-2197: 51.6;U-87 MG: 119.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" NA NA 89000000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" 2.9 0.6 0.5 0.1 3.9 0.7 94.3 0.4 1.3 465.7 0.3 1.0 0.0 0.5 0.0 1056.2 0.2 0.3 1.4 0.5 0.4 0.4 1.7 0.9 0.0 0.5 0.4 0.7 1.5 0.0 0.9 0.3 0.5 0.5 0.0 0.0 351.8 0.0 13.1 2444.7 0.7 0.2 0.4 0.5 1.1 1.0 0.5 6.5 0.7 0.0 168.9 1.1 756.5 0.4 0.1 0.1 0.0 0.1 62.2 107.5 0.1 5.1 7.2 2.4 0.9 0.0 0.1 0.1 1.2 4.8 1.7 0.3 0.0 1.8 1.0 0.1 0.2 0.0 0.1 0.0 0.6 0.0 0.1 146.1 8.2 30.0 7.1 2.1 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.4 0.3 0.2 0.0 0.4 18.4 3.8 51.6 1.4 0.5 0.3 0.0 119.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.9 0.4 1.3 0.5 0.4 0.5 0.4 0.5 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 89.3 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.4 0.8 1.8 0.0 0.0 0.2 0.6 0.2 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 4.0 0.0 0.2 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 1.0 0.2 0.2 13.4 1017.6 0.3 0.7 0.0 0.0 0.4 SCGB2A2 "MGB1, MGC71974, PSBP1, UGB2" ENSG00000110484 "Secretoglobin family 2A member 2" Q13296 11 62270158-62273160 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "breast: 2805.9;skin 1: 708.1" "Group enriched" "Detected in some" 11 "Breast glandular cells: 2119.6;Breast myoepithelial cells: 1028.8;Melanocytes: 1762.7" "Cancer enriched" "Detected in many" 23 "breast cancer: 823.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 124 "SK-BR-3: 18.0" CAB026270 Enhanced "Secreted in female reproductive system" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "CAB026270: AB_912980" "unprognostic (2.38e-1)" "unprognostic (7.28e-2)" "prognostic favorable (9.57e-8)" "unprognostic (4.17e-1)" "unprognostic (3.75e-1)" 34.4 0.2 0.0 0.0 0.0 0.0 2805.9 0.0 0.0 309.2 0.0 0.4 0.0 4.1 0.0 76.6 0.1 0.0 4.0 0.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 1.6 1.3 0.0 0.2 0.0 0.0 159.3 0.1 1.8 708.1 0.2 0.0 0.0 0.2 0.3 1.1 0.0 2.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.6 49.6 0.3 0.0 0.0 0.0 2119.6 1028.8 0.1 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 1.4 41.9 21.6 11.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 141.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 3.2 1762.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 10.9 0.0 9.2 0.0 0.0 0.0 SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Cell type enhanced" "Detected in many" "Ductal cells: 10.0;Ionocytes: 10.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.5;hTCEpi: 12.1;MCF7: 8.3;RT4: 20.6;SCLC-21H: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" 0.5 0.1 0.0 0.9 0.1 0.4 4.4 0.0 0.1 1.2 0.1 2.4 5.6 1.3 1.9 3.6 1.7 1.1 0.6 0.0 0.2 1.9 1.8 1.6 1.3 0.1 0.1 0.3 3.2 2.1 1.3 0.3 0.1 1.7 1.7 0.0 3.1 0.9 0.0 9.2 4.7 1.1 0.0 0.8 2.6 1.1 0.2 1.6 1.9 0.0 2.4 2.3 2.4 0.0 3.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.9 0.0 1.8 0.0 0.4 9.5 0.0 6.5 0.0 0.0 0.6 0.0 1.7 0.0 0.3 0.0 0.0 0.3 12.1 1.5 5.9 0.0 0.0 0.0 1.6 0.0 0.8 8.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 2.5 20.6 8.2 0.0 0.2 4.3 0.0 0.2 0.1 0.0 0.2 0.0 4.3 0.0 0.0 4.0 5.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 1.1 2.3 0.7 1.2 0.1 1.0 2.2 1.6 0.0 2.0 0.0 0.1 1.5 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.0 0.0 1.1 0.0 2.7 5.9 3.5 6.1 6.2 0.0 5.8 3.9 2.6 7.2 3.3 1.8 0.0 0.6 1.1 2.7 3.9 10.0 1.3 2.8 0.7 0.5 2.4 0.4 0.0 7.5 0.2 0.4 1.1 3.2 0.0 0.4 0.0 3.7 0.0 0.0 0.0 6.0 10.2 0.0 0.3 2.0 0.0 0.2 1.8 0.0 0.0 0.0 1.0 0.0 0.1 6.3 4.5 0.0 1.1 3.8 9.7 2.9 3.6 0.0 0.0 0.0 0.5 8.4 6.2 5.6 9.1 0.3 1.2 0.1 4.1 4.4 SDR9C7 "RDHS, SDR-O" ENSG00000170426 "Short chain dehydrogenase/reductase family 9C member 7" Q8NEX9 12 56923133-56934408 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.5;skin 1: 58.5;vagina: 21.3" "Group enriched" "Detected in some" 5 "Early spermatids: 1.2;Suprabasal keratinocytes: 4.0" "Group enriched" "Detected in some" 6 "cervical cancer: 3.0;head and neck cancer: 11.0;melanoma: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (6.75e-2)" "unprognostic (1.42e-1)" "unprognostic (7.90e-5)" "unprognostic (7.93e-2)" "unprognostic (4.20e-3)" "unprognostic (1.26e-1)" "unprognostic (4.74e-2)" "unprognostic (9.31e-2)" "unprognostic (3.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.27e-1)" "unprognostic (1.74e-3)" 0.1 0.0 0.1 0.0 0.1 0.0 2.6 0.2 0.3 11.3 0.0 0.3 0.0 0.4 0.0 14.5 0.2 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.1 0.0 0.8 58.5 0.1 0.0 0.0 0.2 0.1 0.8 0.0 0.5 0.0 0.0 7.5 0.2 21.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.0 0.0 0.0 0.0 0.0 0.0 SERPINB12 YUKOPIN ENSG00000166634 "Serpin family B member 12" Q96P63 18 63542369-63569329 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 13.9;skin 1: 59.1;vagina: 25.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "cervical cancer: 7.3;head and neck cancer: 2.1;lung cancer: 1.9;melanoma: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 8200000 "Cluster 31: Skin - Epidermis development" "unprognostic (7.35e-2)" "prognostic favorable (1.76e-4)" "unprognostic (1.57e-1)" "unprognostic (2.00e-1)" "unprognostic (8.10e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 3.3 0.4 0.2 13.9 0.2 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.2 59.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 3.4 0.0 0.1 2.1 0.0 25.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 SERPINB7 MEGSIN ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 38.4;skin 1: 129.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 79.5;Basal respiratory cells: 353.3;Club cells: 120.7;Ductal cells: 157.8;Extravillous trophoblasts: 82.2;Pancreatic endocrine cells: 276.5" "Cancer enhanced" "Detected in many" "cervical cancer: 8.0;head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 240.4;fHDF/TERT166: 170.8;HaCaT: 412.8;HBEC3-KT: 131.9;HBF TERT88: 223.0;hTERT-HME1: 130.9;U-138 MG: 219.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 12.9;hippocampal formation: 11.4" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" Mitochondria "HPA024200: AB_1856730" "unprognostic (8.66e-3)" "unprognostic (6.31e-3)" "unprognostic (6.55e-2)" "unprognostic (4.03e-4)" "unprognostic (9.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (9.99e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (2.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.62e-1)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-3)" 0.5 0.0 0.0 0.4 0.0 0.0 13.0 0.0 0.0 3.0 0.0 0.7 0.0 0.7 0.0 1.8 0.0 0.3 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.7 0.0 0.5 129.5 0.0 0.1 0.0 0.0 0.7 0.4 0.1 4.5 0.0 0.0 38.4 0.0 4.8 0.0 28.2 0.1 0.0 0.1 0.0 3.7 0.0 240.4 48.2 36.0 26.6 0.0 1.0 0.1 0.1 170.8 62.5 412.8 0.1 131.9 223.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 8.6 22.9 5.5 130.9 1.8 0.0 0.0 0.0 0.8 21.7 0.0 0.0 0.0 0.6 0.0 11.9 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.8 0.1 0.2 0.0 219.4 8.1 4.7 22.8 0.1 0.0 0.0 22.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 79.5 0.9 353.3 0.0 0.0 0.1 0.0 0.0 0.0 120.7 0.0 0.0 1.9 0.0 0.5 0.0 157.8 0.1 0.0 0.0 0.5 0.0 0.0 0.2 8.8 82.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 2.0 0.0 3.0 0.0 0.0 0.2 3.6 0.0 1.6 0.0 0.0 0.5 0.3 276.5 1.1 0.0 0.0 4.5 0.0 0.3 13.0 0.0 0.0 0.0 5.4 0.0 0.2 0.0 21.9 6.2 0.1 0.0 0.0 8.2 SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 58.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 120.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" 10.8 9.5 2.6 15.8 3.2 30.3 9.5 3.4 3.6 9.3 3.5 8.6 6.3 4.7 1.5 30.1 4.4 18.1 5.7 2.8 3.9 9.0 37.8 12.1 13.4 5.2 4.0 4.2 7.1 2.7 3.7 7.2 4.8 4.6 9.7 2.3 10.8 3.3 3.0 58.8 8.8 7.3 4.3 7.8 7.1 2.7 4.6 6.5 5.3 2.3 18.3 23.7 17.1 4.5 24.2 4.8 4.0 28.8 13.9 19.7 2.0 75.6 72.9 46.8 46.4 1.0 10.8 0.4 27.2 45.6 23.3 38.3 0.8 48.2 66.3 33.4 0.9 0.0 8.7 2.5 32.1 120.0 10.0 19.1 41.3 63.6 20.9 30.3 51.4 5.1 0.7 13.4 32.9 2.1 2.1 13.5 1.7 3.8 23.6 1.7 10.5 2.1 21.4 27.1 2.3 2.4 15.0 2.3 28.8 3.3 0.8 45.4 79.2 71.0 15.4 8.8 31.1 5.9 1.0 0.1 72.5 69.2 63.0 2.7 44.2 2.0 7.6 34.2 6.8 7.1 6.3 4.7 53.8 9.9 3.3 5.2 12.4 4.6 18.1 28.8 8.9 11.2 2.6 3.2 3.4 3.6 2.8 3.9 5.2 4.0 4.8 4.3 4.6 4.5 6.0 3.2 8.3 0.3 9.1 41.0 25.9 38.9 5.7 0.4 5.5 3.8 1.2 8.6 25.5 0.0 0.0 4.9 13.4 12.3 0.0 30.0 1.3 7.6 3.3 8.7 1.8 3.0 1.8 19.2 5.6 8.6 8.2 16.3 4.5 0.9 7.5 9.6 15.3 0.0 1.3 3.5 12.2 24.8 35.1 1.1 0.9 35.9 16.0 1.0 29.0 1.6 5.2 1.5 2.9 42.2 10.7 0.0 3.5 13.0 8.5 2.9 12.9 0.3 0.0 12.3 9.8 1.7 2.3 18.2 48.4 31.3 8.2 1.4 5.0 33.3 SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936578-146081791 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 58.1;skeletal muscle: 42.4;skin 1: 56.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 7869.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 6.1;cerebral cortex: 4.1;thalamus: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 70.3;GAMG: 29.8;hTERT-RPE1: 33.5" "Region enriched" "Detected in many" 14 "basal ganglia: 26.7" "Region enhanced" "Detected in many" "basal ganglia: 9.7" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA035903: AB_10696515, HPA058119: AB_2683611" "unprognostic (8.90e-3)" "unprognostic (2.00e-3)" "unprognostic (5.11e-3)" "unprognostic (1.66e-2)" "unprognostic (1.45e-3)" "unprognostic (1.47e-2)" "unprognostic (9.96e-3)" "unprognostic (8.22e-2)" "unprognostic (3.92e-1)" "unprognostic (7.37e-3)" "unprognostic (2.44e-3)" "unprognostic (1.66e-1)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.13e-3)" 1.9 0.9 0.6 2.5 6.1 0.0 4.7 0.0 4.1 7.6 0.2 14.3 16.0 1.1 3.6 34.1 6.1 11.9 58.1 0.9 0.5 0.9 7.0 2.7 0.2 0.0 0.3 0.4 15.4 0.0 1.6 0.1 0.0 2.7 14.3 0.5 12.1 0.6 42.4 56.8 13.7 1.1 0.0 0.0 20.5 6.8 1.7 1.0 6.3 8.8 7.7 1.2 20.6 0.4 21.0 5.7 0.2 1.1 0.0 0.0 0.0 0.2 1.7 4.1 1.7 70.3 19.0 0.0 10.5 0.9 29.8 18.9 0.0 22.4 4.0 0.3 0.3 0.0 8.5 9.5 1.2 0.0 0.0 0.2 11.9 6.4 14.8 33.5 0.2 0.5 0.0 0.0 1.8 0.1 0.0 0.0 1.6 17.3 1.5 0.0 0.2 0.0 8.7 2.0 0.0 0.0 1.2 0.4 0.5 1.0 6.6 0.1 9.8 0.8 17.3 1.5 6.7 0.0 0.0 0.0 10.6 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.6 6.1 0.0 4.1 0.9 0.5 0.0 0.3 0.0 0.0 1.7 0.4 4.1 16.0 2.3 1.6 0.0 55.1 5.4 14.5 38.7 0.4 3.9 3.3 510.0 8.6 6.7 1.8 0.0 0.2 0.2 38.9 0.0 5.7 1511.3 11.9 0.9 9.7 1.2 0.0 10.5 8.7 0.0 15.4 50.4 26.7 1.3 0.1 0.7 8.4 0.2 0.0 2.2 16.1 8.2 0.0 4.9 7869.1 25.7 2.6 8.8 10.3 0.6 1.6 0.0 1.5 0.7 21.4 22.9 34.6 0.6 2.2 26.6 0.9 4.4 0.1 13.1 1.6 6.3 31.4 20.7 70.9 50.0 0.0 0.7 2.9 33.2 6.6 SIK1B ENSG00000275993 "Salt inducible kinase 1B (putative)" A0A0B4J2F2 21 6111131-6123778 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 243.9" "Cell type enhanced" "Detected in some" "Adipocytes: 11.9;Alveolar cells type 1: 25.6;Alveolar cells type 2: 27.2;Endometrial ciliated cells: 17.1;Glandular and luminal cells: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 95.3;hTERT-RPE1: 117.7;Karpas-707: 120.6;LHCN-M2: 83.0;SiHa: 87.2" "HPA038211, HPA078064" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "HPA038211: AB_2675894, HPA078064: " "unprognostic (2.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.57e-2)" "unprognostic (8.85e-2)" "unprognostic (3.32e-2)" "unprognostic (2.44e-1)" "unprognostic (6.58e-3)" "unprognostic (2.62e-2)" "unprognostic (6.56e-2)" "unprognostic (3.15e-2)" "unprognostic (5.52e-3)" "unprognostic (1.01e-2)" "unprognostic (9.09e-2)" "unprognostic (2.88e-2)" "unprognostic (2.41e-1)" "unprognostic (2.69e-3)" "unprognostic (7.41e-2)" 67.6 52.0 6.5 16.1 5.6 42.4 53.5 5.3 12.3 21.8 7.4 22.2 7.6 16.2 0.4 32.0 31.0 30.4 49.9 6.1 11.2 21.8 71.2 38.1 9.8 10.7 8.0 93.5 47.0 8.0 39.5 14.2 8.3 33.5 12.3 20.9 41.5 41.6 40.1 243.9 17.4 10.5 6.2 18.0 37.5 7.3 7.1 8.2 17.9 4.3 4.7 44.3 46.7 5.7 9.5 47.5 3.5 3.0 0.7 0.4 8.3 1.1 0.6 1.7 1.0 53.3 7.0 3.2 1.4 0.2 7.1 0.8 5.5 0.0 0.6 8.9 1.7 7.4 95.3 10.3 3.1 1.2 0.7 1.2 39.6 4.8 26.5 117.7 2.0 1.5 3.0 120.6 83.0 4.7 0.9 2.3 4.9 8.8 5.1 2.0 21.1 14.3 4.6 16.4 4.4 2.1 87.2 5.5 5.0 2.3 0.9 4.1 2.3 1.4 4.4 2.0 19.9 15.9 37.7 1.6 12.6 3.0 5.6 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.6 1.8 0.0 0.0 6.5 5.6 5.3 12.3 6.1 11.2 10.7 8.0 8.3 6.2 7.1 5.7 11.9 25.6 27.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 4.0 2.7 0.0 0.0 3.7 1.8 0.0 0.7 4.1 0.0 0.0 0.5 0.0 17.1 3.4 1.4 0.0 0.0 0.0 0.2 0.9 1.5 0.0 30.0 6.3 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.1 0.0 0.0 0.2 8.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.5 2.4 0.0 0.0 0.0 SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 63.6;Syncytiotrophoblasts: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.6" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" 23.3 22.9 6.1 13.1 6.2 34.0 21.0 6.8 7.9 27.1 5.8 22.5 13.9 29.6 18.4 31.2 22.8 21.3 23.2 5.9 6.1 20.6 10.3 22.7 15.1 7.4 6.8 40.8 22.8 9.6 18.8 21.1 7.4 22.9 8.3 2.0 17.4 15.7 18.3 42.9 18.7 13.5 6.9 19.3 18.9 8.9 8.1 9.8 20.6 9.4 11.2 31.8 26.0 7.7 66.4 27.0 7.3 38.3 25.2 27.6 48.9 49.2 29.2 32.5 32.3 25.0 31.8 51.0 91.1 46.8 41.3 55.9 24.4 24.7 8.6 32.7 11.8 15.9 36.0 20.3 47.0 19.0 24.9 34.8 28.1 29.9 15.8 28.5 22.6 8.7 17.6 48.6 21.6 90.0 10.2 17.0 5.9 32.4 54.9 16.8 19.9 38.8 24.7 24.2 6.8 12.0 29.8 55.4 13.0 8.5 17.9 15.0 29.5 38.0 23.9 89.6 63.2 34.3 35.6 52.8 40.9 39.6 20.2 218.6 4.5 21.1 12.9 6.5 9.6 5.3 8.5 9.2 3.9 5.2 6.0 5.9 6.1 8.8 5.6 9.5 6.4 6.3 6.1 6.2 6.8 7.9 5.9 6.1 7.4 6.8 7.4 6.9 8.1 7.7 13.3 3.2 7.0 2.3 21.1 22.6 27.1 15.2 50.7 2.8 13.7 11.8 4.0 15.7 7.3 18.4 6.2 49.5 17.4 22.1 7.9 17.8 3.6 13.0 14.8 15.8 10.2 11.1 1.6 19.4 63.6 21.2 13.7 21.0 12.7 15.8 16.8 2.3 19.4 3.3 1.4 15.5 4.1 8.4 19.6 1.2 27.1 22.7 3.6 1.0 13.2 3.0 23.7 1.5 1.6 20.9 16.0 13.2 19.8 14.1 17.2 10.4 6.9 1.9 6.6 12.1 14.3 1.9 2.9 45.5 27.8 103.0 24.5 5.4 11.7 23.5 SLC10A6 SOAT ENSG00000145283 "Solute carrier family 10 member 6" Q3KNW5 4 86823468-86849384 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.1;skin 1: 13.4" "Group enriched" "Detected in some" 5 "Early spermatids: 59.5;Late spermatids: 191.7" "Group enriched" "Detected in many" 5 "cervical cancer: 3.5;head and neck cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;BJ hTERT+: 1.2;HaCaT: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA016662 Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "HPA016662: AB_1669899" "unprognostic (2.79e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (8.31e-3)" "unprognostic (5.88e-2)" "unprognostic (8.87e-3)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-1)" "unprognostic (3.84e-4)" "unprognostic (1.54e-1)" "unprognostic (2.06e-1)" "unprognostic (9.22e-2)" "unprognostic (5.89e-4)" 5.2 0.3 0.1 0.7 0.3 0.0 2.8 0.1 0.2 3.1 0.0 0.4 0.1 0.5 0.3 9.1 0.6 1.0 0.7 0.1 0.4 0.1 0.1 0.3 0.1 0.2 0.3 0.1 0.7 0.6 0.2 0.1 0.3 0.4 0.3 0.0 1.5 0.2 0.7 13.4 0.2 1.0 0.1 0.2 0.3 4.3 0.9 0.3 1.0 1.1 1.2 0.9 4.7 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.1 0.9 0.7 9.3 0.0 0.0 6.2 0.0 13.8 0.0 0.8 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.5 1.7 1.0 2.6 0.0 0.0 2.5 0.0 0.1 0.6 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.2 191.7 1.5 0.1 0.0 2.8 0.0 0.0 0.0 3.5 4.8 0.1 0.0 0.4 1.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 1.2 1.2 0.6 6.0 24.9 0.0 0.0 0.0 0.0 0.2 SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 129.9;Karpas-707: 117.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" 18.6 20.7 9.6 7.3 10.5 4.6 16.2 10.1 9.2 14.5 8.4 10.1 7.9 11.9 7.3 22.0 10.7 7.3 13.8 9.6 11.8 19.5 17.7 11.9 6.5 13.9 12.9 8.5 10.3 21.3 10.8 9.4 12.3 11.4 5.7 5.8 14.5 8.1 12.8 21.2 10.0 10.1 10.4 10.8 11.3 5.1 13.0 5.7 16.0 9.9 7.6 12.1 13.0 11.6 24.6 43.6 12.3 32.6 41.7 19.4 20.4 14.9 20.3 16.8 15.2 27.9 44.5 6.6 23.4 18.7 42.0 29.4 18.1 26.9 11.8 11.5 10.1 7.6 16.4 23.3 129.9 7.8 36.4 29.8 26.9 18.9 62.7 7.6 19.9 9.6 14.2 117.3 16.9 40.5 10.0 7.0 7.6 17.2 10.9 8.9 35.9 10.9 44.1 20.3 9.6 12.7 22.8 37.4 25.4 10.1 14.1 8.2 19.2 21.8 24.0 30.7 15.2 23.9 32.6 12.9 23.6 13.4 21.0 12.1 18.1 8.0 11.9 25.6 7.0 4.8 8.2 10.8 11.4 3.6 5.3 7.9 11.7 13.6 30.9 7.8 5.9 9.5 9.6 10.5 10.1 9.2 9.6 11.8 13.9 12.9 12.3 10.4 13.0 11.6 39.0 12.8 10.5 11.8 5.9 17.0 13.2 10.2 7.4 17.2 17.5 10.2 13.5 28.6 11.1 33.1 6.2 24.1 12.0 21.5 7.9 34.2 1.7 13.4 29.7 20.8 9.1 0.8 6.9 38.7 22.3 25.2 12.2 22.8 1.3 11.9 31.8 25.4 51.2 15.2 7.9 11.2 8.2 61.0 16.8 1.5 18.3 28.8 28.4 4.7 19.8 19.2 11.3 9.0 10.8 48.2 14.3 12.0 5.5 18.3 21.5 57.2 9.0 11.1 26.3 17.8 20.2 3.7 7.1 14.9 25.7 38.0 10.6 16.8 11.2 11.7 SLC39A2 ZIP2 ENSG00000165794 "Solute carrier family 39 member 2" Q9NP94 14 20999255-21001871 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;seminal vesicle: 33.2;skin 1: 37.5" "Cell type enhanced" "Detected in some" "Muller glia cells: 22.3;Squamous epithelial cells: 12.0;Suprabasal keratinocytes: 6.0;Urothelial cells: 4.4" "Group enriched" "Detected in many" 4 "cervical cancer: 5.1;colorectal cancer: 3.3;head and neck cancer: 6.1;melanoma: 1.9;urothelial cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 71 "HaCaT: 23.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA030489, HPA073231" Uncertain Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "Cytoplasmic bodies" "HPA030489: AB_10601488, HPA073231: " "unprognostic (2.76e-2)" "unprognostic (4.86e-2)" "unprognostic (9.72e-2)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "unprognostic (2.71e-1)" "unprognostic (3.42e-1)" "unprognostic (1.70e-1)" "unprognostic (4.43e-1)" "unprognostic (6.20e-3)" "unprognostic (3.31e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-2)" "unprognostic (1.91e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-1)" "unprognostic (2.30e-3)" 0.1 0.0 0.2 0.1 0.2 0.0 1.9 0.3 0.3 8.0 0.2 1.9 0.0 0.3 0.1 18.8 0.5 0.4 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 2.3 0.1 0.3 0.2 12.2 1.3 3.7 4.1 33.2 0.2 37.5 0.1 0.2 0.3 0.0 0.0 0.1 0.3 2.8 0.0 0.0 2.7 0.3 14.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 0.0 0.2 0.8 0.3 0.4 0.0 0.7 0.0 2.1 0.1 0.0 0.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 22.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 12.0 6.0 0.3 0.0 0.0 1.4 4.4 SLC46A2 "Ly110, TSCOT" ENSG00000119457 "Solute carrier family 46 member 2" Q9BY10 9 112878920-112890876 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 16.5;lung: 10.4;lymphoid tissue: 16.0;skin 1: 24.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 39.8;Endometrial ciliated cells: 15.8;Glandular and luminal cells: 6.9;Kupffer cells: 11.8;monocytes: 12.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 24.6;intermediate monocyte: 12.1" "Lineage enriched" "Detected in many" 5 "monocytes: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020098 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 11: Alveolar cells - Smell perception" "HPA020098: AB_2670363" "unprognostic (1.26e-1)" "unprognostic (5.15e-3)" "unprognostic (1.10e-2)" "unprognostic (1.53e-3)" "unprognostic (3.57e-3)" "unprognostic (2.10e-2)" "unprognostic (4.56e-1)" "unprognostic (2.18e-1)" "unprognostic (8.10e-2)" "unprognostic (1.50e-3)" "unprognostic (3.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.77e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-2)" "unprognostic (1.83e-1)" "unprognostic (7.82e-2)" 0.1 0.0 0.1 0.6 0.1 0.1 0.9 0.5 0.2 16.5 0.0 0.0 0.0 3.0 4.7 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 10.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 1.5 0.0 24.1 0.0 0.4 0.0 0.9 0.0 0.6 0.5 16.0 0.0 0.0 0.1 3.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.1 12.1 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.0 10.1 0.2 0.0 6.6 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.3 0.0 0.0 39.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 15.8 0.8 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 6.9 0.0 0.0 0.4 0.1 2.1 0.0 0.4 0.0 0.0 11.8 1.8 4.4 0.0 4.1 0.0 0.0 12.4 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 SNX21 "C20orf161, dJ337O18.4, SNX-L" ENSG00000124104 "Sorting nexin family member 21" Q969T3 20 45833799-45843276 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Theca cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.8;classical monocyte: 1.6;eosinophil: 4.8;intermediate monocyte: 2.6;non-classical monocyte: 2.0" "Group enriched" "Detected in many" 8 "granulocytes: 4.8;monocytes: 2.6" "Cell line enhanced" "Detected in many" "EFO-21: 17.9;PC-3: 29.8;U-87 MG: 18.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046359 Approved Approved "Vesicles,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Centriolar satellite" "HPA046359: AB_10963216" "unprognostic (1.97e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (4.16e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (4.96e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-2)" "unprognostic (2.18e-1)" 25.0 27.8 4.9 1.1 4.1 0.7 18.7 5.8 7.9 26.4 4.9 15.8 3.7 28.6 0.8 14.1 24.6 5.0 14.9 3.5 2.8 11.9 6.2 10.9 1.3 9.2 5.1 30.5 4.2 3.3 10.9 2.9 6.5 14.4 1.2 0.7 9.7 4.8 31.9 47.9 7.5 1.9 3.0 7.3 11.3 6.1 7.2 0.5 9.1 6.7 0.6 25.7 19.5 4.6 4.3 6.7 1.0 6.5 7.8 7.5 4.3 6.8 5.0 5.0 4.0 5.0 3.0 0.1 17.9 4.8 4.1 5.5 0.2 4.5 0.8 0.3 1.4 0.1 4.1 4.6 3.3 0.0 1.3 3.9 2.7 4.8 0.4 1.7 3.6 1.1 0.1 0.0 0.9 11.1 0.1 0.8 1.8 0.8 29.8 0.1 0.5 0.2 1.0 0.7 1.2 11.6 14.6 10.3 8.1 0.8 5.9 1.2 6.4 6.0 7.2 17.2 5.5 0.2 0.9 0.2 18.1 0.0 4.4 2.8 1.6 4.8 0.0 2.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 2.0 0.1 0.4 0.3 4.9 4.1 5.8 7.9 3.5 2.8 9.2 5.1 6.5 3.0 7.2 4.6 11.1 9.6 8.3 25.1 1.0 10.1 4.7 6.4 8.6 18.4 8.6 8.5 4.8 7.2 10.3 5.5 8.4 4.9 0.4 10.3 25.4 10.3 3.7 5.0 27.0 10.3 9.0 0.0 4.8 11.7 5.2 37.0 6.6 7.5 0.0 27.0 10.4 4.3 4.8 15.2 5.7 9.2 4.1 7.1 10.0 18.3 19.6 5.4 10.6 3.7 3.3 14.8 1.0 8.5 6.5 8.4 5.9 17.0 0.8 3.7 15.9 15.7 6.6 15.6 6.6 16.4 20.1 0.9 2.4 4.1 22.7 2.5 2.2 62.2 7.0 3.4 SP5 ENSG00000204335 "Sp5 transcription factor" Q6BEB4 2 170715337-170718078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 8.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.8;Cardiomyocytes: 3.1;Distal tubular cells: 3.9;Endometrial stromal cells: 7.1;Fibroblasts: 4.4;Intestinal goblet cells: 4.3;Spermatogonia: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 122.1" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Low region specificity" "Detected in some" HPA074123 Approved Nucleoplasm,Nucleoli NA NA "Cluster 31: Skin - Epidermis development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA074123: AB_2686664" "unprognostic (1.16e-2)" "unprognostic (6.99e-2)" "unprognostic (3.41e-2)" "unprognostic (2.10e-2)" "unprognostic (1.14e-1)" "unprognostic (9.52e-3)" "unprognostic (1.45e-1)" "unprognostic (4.60e-2)" "unprognostic (4.77e-1)" "unprognostic (8.97e-3)" "unprognostic (1.79e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-8)" "unprognostic (8.05e-3)" "unprognostic (2.49e-1)" "unprognostic (2.41e-2)" "unprognostic (2.17e-1)" 2.5 1.2 0.5 0.2 0.5 0.0 1.4 2.2 0.3 8.8 0.5 1.5 1.0 3.7 0.4 1.2 1.2 0.2 0.2 0.2 1.4 0.2 2.1 0.5 0.2 0.3 1.4 0.4 0.4 0.3 0.1 0.2 0.2 1.7 0.2 0.0 1.5 0.2 0.2 4.6 1.4 0.1 0.0 0.0 3.1 0.8 1.8 0.1 0.1 0.0 0.8 1.5 2.2 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 27.7 0.1 0.0 0.5 0.0 0.5 1.5 0.3 0.0 0.0 3.5 0.3 0.4 0.1 122.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 2.0 2.3 0.0 0.0 0.0 0.1 0.0 0.1 0.3 4.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 2.2 0.3 0.2 1.4 0.3 1.4 0.2 0.0 1.8 0.2 0.2 0.0 0.0 0.3 0.0 0.8 0.1 0.0 2.8 0.0 0.2 0.3 3.1 0.0 0.0 1.8 0.0 1.5 0.1 0.3 3.9 0.0 0.2 2.3 7.1 0.5 0.0 0.0 0.0 0.0 0.0 4.4 0.0 1.3 0.0 0.0 0.0 2.5 0.2 0.0 0.4 4.3 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.4 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.7 0.2 0.1 0.3 0.2 0.0 1.6 0.0 SP6 "Epfn, KLF14" ENSG00000189120 "Sp6 transcription factor" Q3SY56 17 47844908-47855874 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 22.8;skin 1: 14.6" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 57.5;Syncytiotrophoblasts: 98.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 11.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 92.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024516, HPA044469" Supported "Nucleoplasm,Mitotic spindle,Centrosome" Yes No "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Mitotic spindle, Centrosome" "HPA024516: AB_10960551, HPA044469: AB_10966430" "unprognostic (3.06e-2)" "unprognostic (4.32e-2)" "unprognostic (1.07e-2)" "unprognostic (7.55e-3)" "unprognostic (6.79e-2)" "unprognostic (4.57e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.11e-6)" "unprognostic (1.22e-1)" "unprognostic (8.72e-2)" "unprognostic (3.92e-3)" "unprognostic (1.63e-1)" "unprognostic (9.59e-3)" "prognostic favorable (6.39e-4)" "unprognostic (3.33e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.72e-4)" 0.9 0.9 0.1 0.6 0.1 0.0 3.9 0.4 0.1 1.3 0.1 1.4 1.6 0.3 3.9 5.5 1.1 0.1 0.3 0.1 0.2 1.0 0.0 3.1 0.6 0.7 0.4 0.9 0.4 6.2 0.2 22.8 1.0 1.8 0.7 0.1 0.9 10.2 0.1 14.6 4.7 0.3 0.5 0.8 0.3 0.2 0.2 1.1 1.1 0.1 1.9 2.7 3.9 0.1 6.8 0.8 0.0 0.0 0.0 0.0 92.3 0.4 0.4 1.8 0.4 20.1 1.9 0.0 0.6 0.0 1.3 2.8 0.1 3.4 0.5 0.2 0.7 0.1 1.5 0.6 0.1 0.0 0.0 0.1 1.8 0.0 1.8 0.2 0.2 0.2 4.7 0.1 0.1 1.8 0.0 0.1 0.0 8.2 1.6 0.0 0.0 0.2 0.5 11.9 2.9 0.1 0.1 11.9 0.0 16.8 4.8 0.0 6.3 0.4 2.6 0.0 0.5 0.8 0.0 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.2 0.7 0.4 1.0 0.5 0.2 0.1 1.3 0.0 0.0 1.0 0.2 0.1 2.6 4.6 4.0 0.0 6.0 6.1 0.5 0.0 0.8 1.8 0.0 57.5 0.3 5.2 0.0 0.7 0.1 0.4 0.1 2.7 1.8 0.0 0.2 0.8 3.9 0.7 0.0 0.7 0.0 0.2 0.7 0.1 4.1 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 3.2 0.0 0.1 3.8 13.4 0.0 1.0 0.0 0.0 0.0 0.2 0.3 0.6 1.1 0.9 98.8 0.3 0.1 3.3 6.3 SPTSSB "ADMP, C3orf57, ssSPTb" ENSG00000196542 "Serine palmitoyltransferase small subunit B" Q8NFR3 3 161344792-161372880 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 45.5;stomach 1: 61.4;urinary bladder: 49.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.5;Exocrine glandular cells: 46.0;Gastric mucus-secreting cells: 37.2;Melanocytes: 46.2;Prostatic glandular cells: 74.6;Suprabasal keratinocytes: 36.4;Urothelial cells: 65.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 24.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 13 "NK-cell: 353.6" "Lineage enriched" "Detected in many" 13 "NK-cells: 353.6" "Group enriched" "Detected in some" 10 "MCF7: 1167.1;RT4: 304.2" HPA047712 Uncertain "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "Nuclear speckles" "HPA047712: AB_2680127" "unprognostic (2.09e-1)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "unprognostic (1.34e-2)" "unprognostic (4.15e-2)" "unprognostic (3.18e-2)" "unprognostic (1.98e-1)" "unprognostic (5.10e-2)" "unprognostic (6.37e-3)" "unprognostic (2.72e-1)" "unprognostic (4.08e-2)" "unprognostic (5.37e-4)" "unprognostic (8.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (9.51e-3)" 1.9 0.1 3.7 0.6 1.9 0.3 8.3 5.2 7.9 4.8 3.0 0.8 0.3 1.0 0.1 8.7 0.4 1.3 0.4 2.2 1.3 1.2 0.5 0.1 1.2 2.8 5.6 0.2 0.8 0.1 0.4 0.0 4.8 14.7 0.7 2.5 11.4 0.1 0.1 45.5 0.3 0.2 0.2 1.3 61.4 0.0 6.7 0.4 0.3 1.5 2.0 49.5 11.1 3.7 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.9 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.4 0.0 0.0 0.1 0.1 2.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1167.1 0.0 0.0 4.3 71.5 13.4 0.0 0.0 0.5 0.0 304.2 1.9 11.9 0.0 40.6 0.0 0.1 64.7 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.1 0.2 26.2 0.1 0.9 2.5 0.0 0.1 0.3 0.4 0.9 353.6 0.0 0.2 0.0 2.5 3.7 1.9 5.2 7.9 2.2 1.3 2.8 5.6 4.8 0.2 6.7 3.7 0.2 0.0 0.0 4.2 0.1 3.8 16.6 19.6 1.8 1.4 16.6 8.4 0.4 1.5 22.5 3.7 0.0 0.0 3.6 0.1 0.0 1.3 0.0 0.5 0.2 0.8 0.0 0.0 28.5 46.0 0.0 0.7 37.2 1.2 0.0 4.3 0.0 0.0 0.2 0.0 14.2 2.5 6.1 0.0 0.8 0.0 0.0 0.4 46.2 1.0 0.1 0.6 7.2 5.0 1.5 27.6 0.0 0.0 0.4 74.6 0.0 0.0 4.1 1.4 0.0 0.1 2.2 0.0 0.0 6.8 36.4 0.1 3.2 0.0 0.0 65.6 SREK1IP1 "FLJ36754, P18SRP, SFRS12IP1" ENSG00000153006 "SREK1 interacting protein 1" Q8N9Q2 5 64718148-64768691 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 300.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045677, HPA062853" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA045677: AB_10964635, HPA062853: AB_2684881" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.17e-2)" "unprognostic (1.06e-1)" "unprognostic (1.51e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (8.60e-3)" "unprognostic (8.67e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.67e-1)" "unprognostic (8.39e-2)" "unprognostic (3.85e-2)" "unprognostic (1.99e-1)" 6.2 5.5 5.1 4.2 5.3 4.6 6.4 6.0 7.2 5.0 5.3 4.9 4.1 5.0 5.6 6.9 4.6 4.3 4.0 5.0 5.4 5.7 5.8 5.6 5.7 5.4 5.2 6.6 4.3 5.8 2.8 8.6 5.6 5.6 4.8 6.4 5.1 5.3 3.6 9.0 4.4 5.5 5.3 5.5 5.2 3.2 5.3 6.9 5.9 4.7 6.0 5.3 4.3 5.8 8.3 4.2 10.5 7.9 9.2 15.1 6.2 12.3 9.9 8.3 11.0 7.8 8.9 8.6 12.4 9.9 7.9 5.3 9.6 18.7 14.5 10.3 11.6 9.4 7.6 7.0 9.5 10.2 9.1 9.9 17.3 11.5 14.8 8.8 12.4 10.6 8.4 5.2 9.9 3.0 18.2 10.3 5.4 2.2 5.6 8.6 8.5 13.8 14.3 6.6 4.5 6.7 7.8 5.5 12.1 7.3 7.0 19.5 12.5 6.0 3.6 7.3 13.0 7.5 13.8 7.7 11.5 15.7 8.3 2.0 1.6 0.7 1.8 1.2 1.8 1.6 1.7 1.7 1.4 1.5 1.7 1.7 0.6 1.5 0.8 3.3 1.6 0.9 5.1 5.3 6.0 7.2 5.0 5.4 5.4 5.2 5.6 5.3 5.3 5.8 69.3 48.1 44.1 20.2 43.8 81.8 62.5 117.8 43.3 51.8 49.0 59.2 31.2 75.8 63.2 86.5 31.3 72.6 54.8 87.3 90.1 72.2 300.6 69.3 66.0 63.1 61.0 79.8 30.8 75.2 84.6 55.8 35.2 86.6 53.8 33.9 91.1 100.3 64.5 97.6 23.4 71.4 89.5 79.7 62.4 179.2 95.7 54.8 39.2 15.9 65.1 59.2 71.1 19.1 25.4 196.8 136.3 72.6 39.1 76.2 66.8 114.8 58.4 43.5 65.7 57.7 56.9 44.3 46.2 47.0 104.0 48.7 50.4 30.5 54.2 83.2 STARD5 MGC10327 ENSG00000172345 "StAR related lipid transfer domain containing 5" Q9NSY2 15 81309053-81324183 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 28.0;Plasma cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 5.8;RPMI-8226: 6.2;U-266/70: 7.1;U-937: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040662 Approved Approved Vesicles,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Cytosol "HPA040662: AB_10959593" "unprognostic (5.35e-4)" "unprognostic (1.55e-1)" "unprognostic (2.58e-2)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (2.22e-4)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.08e-2)" "unprognostic (8.08e-2)" "unprognostic (6.81e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (4.84e-3)" "unprognostic (7.55e-3)" 1.0 0.6 0.6 6.0 0.8 4.3 0.7 3.4 1.3 7.2 1.9 2.8 2.2 4.6 5.0 3.4 1.8 1.3 0.8 0.6 0.7 0.7 5.1 1.1 7.7 0.9 1.0 1.2 0.6 0.6 0.4 1.6 1.2 3.6 3.7 0.4 1.6 2.1 0.6 7.9 4.2 1.8 0.9 6.2 2.1 0.7 0.7 0.5 0.8 0.3 1.5 2.5 5.5 1.4 0.3 0.0 0.0 0.9 2.3 2.3 0.1 0.3 0.3 0.8 1.2 0.1 0.1 4.8 0.0 1.5 0.2 4.0 1.1 1.0 0.6 0.1 0.4 1.8 0.3 0.4 0.5 2.8 5.8 2.0 2.0 0.3 0.6 1.5 0.1 1.9 0.6 1.3 0.5 0.1 0.5 4.0 0.3 0.2 0.0 0.1 0.7 6.2 0.3 1.4 0.3 0.1 0.1 0.5 0.6 0.3 0.6 0.6 0.2 1.3 0.6 1.3 0.1 7.1 1.5 1.8 0.9 6.8 0.4 5.0 1.8 2.3 3.0 2.4 2.5 1.0 2.7 3.2 2.6 0.7 3.9 3.9 1.3 2.6 2.3 1.4 3.6 3.7 0.6 0.8 3.4 1.3 0.6 0.7 0.9 1.0 1.2 0.9 0.7 1.4 3.8 0.0 1.1 0.0 11.4 13.3 12.0 28.0 10.8 1.8 2.7 4.2 0.3 0.0 4.9 0.0 6.2 2.5 4.2 22.1 3.9 1.3 15.2 2.5 14.4 2.5 11.4 2.5 2.2 1.4 4.0 8.5 15.8 2.3 10.2 1.0 3.6 25.4 5.2 1.7 2.0 24.3 2.0 7.9 10.9 1.5 5.0 8.0 1.8 1.9 0.7 1.2 2.1 0.0 0.4 1.8 14.4 9.8 31.5 3.3 23.9 0.7 4.0 0.9 0.0 3.8 2.8 0.9 0.7 19.6 16.3 4.9 4.2 6.3 19.9 9.6 SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.2;skin 1: 65.5;urinary bladder: 40.5" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 184.7;Basal squamous epithelial cells: 520.2;Breast myoepithelial cells: 192.9;Cholangiocytes: 183.0;Extravillous trophoblasts: 201.8;Respiratory ciliated cells: 163.8;Squamous epithelial cells: 132.5" "Group enriched" "Detected in many" 5 "cervical cancer: 10.5;pancreatic cancer: 21.7;urothelial cancer: 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 32.2;hTCEpi: 50.2;T-47d: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047239, HPA052700" Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA047239: , HPA052700: AB_2681920" "unprognostic (1.66e-3)" "unprognostic (2.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "unprognostic (6.31e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (1.36e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (7.09e-2)" "unprognostic (2.48e-1)" "unprognostic (2.33e-6)" "unprognostic (2.87e-2)" "unprognostic (1.75e-1)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" 0.1 0.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 1.3 0.1 0.4 0.5 0.0 0.5 29.2 1.0 8.6 0.0 0.0 0.0 0.3 0.6 4.7 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.6 0.0 2.5 0.0 0.0 20.9 2.9 0.0 65.5 2.5 0.0 0.0 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.1 40.5 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 32.2 0.0 0.0 0.0 0.6 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 50.2 0.0 5.8 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.7 0.0 0.0 0.3 0.0 0.1 1.0 0.0 0.3 0.0 2.7 0.0 0.0 13.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 16.0 3.9 0.0 0.3 184.7 5.6 24.9 520.2 0.0 3.2 192.9 0.6 183.0 39.1 5.5 0.0 28.7 0.7 3.4 0.0 31.1 0.0 15.6 0.1 1.7 0.0 0.0 0.0 9.7 201.8 1.6 12.2 0.6 1.3 0.0 0.0 0.1 7.1 0.0 0.0 1.3 16.2 0.0 14.7 0.0 0.0 1.3 10.6 0.0 0.0 0.0 0.0 0.0 0.0 28.3 3.5 0.0 6.2 1.3 18.3 0.0 163.8 0.0 0.0 0.0 7.0 0.0 0.0 132.5 47.2 36.8 0.6 0.1 1.7 31.5 TFAP2A "AP-2, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.8;skin 1: 66.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 167.9;Cytotrophoblasts: 285.8;Extravillous trophoblasts: 260.6;Squamous epithelial cells: 147.7;Syncytiotrophoblasts: 700.1" "Cancer enhanced" "Detected in many" "melanoma: 45.6" "Group enriched" "Detected in many" 4 "cerebellum: 4.1;medulla oblongata: 3.0;midbrain: 1.3;pons: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 104.7;hTCEpi: 97.3;SuSa: 97.3" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB000326: AB_667767, HPA056871: AB_2683262" "unprognostic (5.97e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-2)" "unprognostic (1.27e-1)" "unprognostic (7.62e-5)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-11)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-4)" "unprognostic (2.25e-2)" 0.5 0.4 0.4 0.1 0.3 0.1 32.8 4.1 0.4 7.5 0.2 1.1 0.5 0.3 21.8 29.9 0.4 0.2 0.9 0.3 0.1 7.4 0.1 0.5 0.4 3.0 1.3 0.4 0.2 0.6 0.4 29.6 2.1 9.8 0.5 8.1 23.5 9.3 0.5 66.7 0.8 0.1 0.5 0.1 1.4 2.2 0.5 0.2 0.5 0.1 5.1 3.5 16.6 0.6 51.8 17.8 0.1 87.9 0.4 0.0 19.7 40.2 30.3 31.7 31.4 2.1 19.3 3.2 4.9 12.0 17.5 53.2 4.3 66.1 30.9 104.7 45.2 0.4 44.5 0.0 0.0 1.7 1.5 0.0 97.3 0.1 66.6 18.3 0.0 0.9 3.3 0.1 0.3 12.2 0.0 17.2 0.5 3.3 24.7 5.9 5.0 2.2 18.8 21.8 12.5 0.3 44.1 82.7 82.3 97.3 56.0 1.7 0.0 9.9 2.7 7.1 25.3 0.1 5.1 0.8 5.1 1.7 59.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.1 0.4 0.3 0.1 3.0 1.3 2.1 0.5 0.5 0.6 0.5 0.0 0.0 0.0 0.4 130.6 45.5 50.3 167.9 25.9 98.2 65.7 2.7 0.0 30.5 31.3 2.1 285.8 0.5 1.0 7.9 2.2 5.3 1.2 0.7 2.1 1.2 0.0 0.0 0.4 260.6 4.2 0.0 1.5 0.0 0.1 0.0 0.0 20.4 80.8 0.0 0.5 46.8 0.0 6.1 3.8 0.6 0.5 124.5 0.0 0.0 4.3 0.0 0.0 0.1 3.7 0.5 0.0 1.2 58.2 0.1 0.3 21.5 4.6 0.0 0.3 4.1 6.5 16.8 147.7 138.4 700.1 0.3 0.3 0.5 46.7 TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.1;skin 1: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 132.4;Basal squamous epithelial cells: 120.1;Breast glandular cells: 66.1;Breast myoepithelial cells: 79.6;Cytotrophoblasts: 91.7;Extravillous trophoblasts: 59.7;Squamous epithelial cells: 81.0;Suprabasal keratinocytes: 149.3;Syncytiotrophoblasts: 105.6" "Cancer enhanced" "Detected in many" "testis cancer: 54.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "BEWO: 190.6;MCF7: 169.2;SK-BR-3: 308.9;T-47d: 86.8;WM-115: 114.7" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB016061: AB_667770, CAB016079: AB_2199447, HPA055179: AB_2682729, HPA057076: AB_2683329" "unprognostic (1.74e-2)" "prognostic favorable (6.90e-4)" "unprognostic (2.24e-2)" "unprognostic (2.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (2.54e-2)" "unprognostic (8.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.61e-1)" "unprognostic (3.14e-3)" "unprognostic (2.63e-1)" "unprognostic (9.04e-5)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "unprognostic (3.28e-2)" 1.8 0.3 1.3 0.2 0.6 0.1 26.1 0.5 1.5 18.3 0.5 4.0 0.2 6.2 5.2 29.1 2.6 1.0 0.3 1.7 0.7 2.0 0.0 2.6 0.1 0.9 0.8 0.3 1.0 2.6 0.8 17.0 1.2 7.1 1.2 2.7 20.7 4.4 2.1 53.3 0.3 1.1 0.5 0.1 0.7 1.0 0.6 0.7 2.3 0.1 3.0 3.9 19.2 1.0 12.8 15.8 0.1 0.2 0.0 0.0 190.6 20.1 36.4 25.0 4.5 3.2 0.3 0.0 1.3 13.3 13.3 42.7 27.3 5.5 17.0 0.1 2.8 0.0 1.7 0.0 0.0 0.0 1.7 0.3 21.4 7.4 7.2 0.0 0.0 8.1 0.2 3.2 0.0 169.2 20.8 1.2 9.5 9.9 20.7 0.1 0.0 7.0 0.0 10.1 5.1 0.1 13.6 308.9 21.8 28.3 86.8 4.6 0.2 16.2 0.4 8.6 15.4 0.1 0.0 0.1 4.0 0.1 114.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.5 1.5 1.7 0.7 0.9 0.8 1.2 0.5 0.6 1.0 0.7 0.0 9.5 3.9 0.3 132.4 29.9 2.4 120.1 4.1 66.1 79.6 1.0 0.0 5.6 9.2 0.0 91.7 1.5 1.7 0.0 0.3 0.3 7.8 18.7 2.0 3.0 0.0 0.0 0.0 59.7 7.4 1.5 16.0 0.0 0.0 0.7 0.0 7.8 0.0 0.0 1.7 10.2 0.3 8.2 0.0 0.0 1.6 21.4 3.7 0.0 0.3 0.0 0.0 0.0 1.0 0.6 0.0 3.8 18.6 0.0 0.0 5.2 0.0 0.0 0.5 2.1 0.0 1.8 81.0 149.3 105.6 1.3 0.0 1.0 18.5 TGM5 "TGMX, TGX" ENSG00000104055 "Transglutaminase 5" O43548 15 43232590-43266928 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 12.0;skin 1: 39.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.6;Club cells: 4.3;Early spermatids: 3.2;Late spermatids: 4.0;Suprabasal keratinocytes: 6.7;Urothelial cells: 12.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HEL: 16.6" "Region enriched" "Detected in single" 12 "cerebellum: 2.6" "Low region specificity" "Detected in many" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (3.17e-2)" "unprognostic (1.03e-2)" "unprognostic (5.92e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-15)" "unprognostic (1.94e-1)" "unprognostic (3.14e-1)" "unprognostic (7.22e-3)" "unprognostic (5.71e-2)" 0.8 0.0 0.0 0.0 0.0 0.2 1.7 0.2 0.0 3.9 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 4.3 1.2 0.3 39.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.3 0.5 7.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.3 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.2 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 2.6 1.5 0.0 0.0 1.0 0.5 0.2 0.0 4.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.2 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 4.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.8 6.7 1.9 0.0 0.0 0.0 12.1 THBD CD141 ENSG00000178726 Thrombomodulin P07204 20 23045633-23049672 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant, Hemolytic uremic syndrome, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 254.3;Endothelial cells: 200.6;Langerhans cells: 138.1;Leydig cells: 130.8;Macrophages: 130.9;Peritubular cells: 259.2;Squamous epithelial cells: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 24.6" "Group enriched" "Detected in many" 7 "dendritic cells: 10.8;granulocytes: 24.6;monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;CAPAN-2: 39.2;EFO-21: 33.5;HaCaT: 33.1;hTCEpi: 42.6;OE19: 29.8;THP-1: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002425, HPA002982" Supported Approved Nucleoplasm,Cytosol NA NA 5550000 1300000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "CAB002425: AB_563497, HPA002982: AB_1078444" "unprognostic (1.96e-1)" "unprognostic (2.93e-3)" "unprognostic (8.70e-2)" "unprognostic (3.00e-2)" "unprognostic (3.07e-2)" "unprognostic (1.88e-1)" "unprognostic (7.81e-3)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.33e-2)" "unprognostic (2.23e-2)" "unprognostic (7.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.58e-3)" "unprognostic (9.71e-2)" 65.4 11.4 2.0 19.6 1.8 15.5 25.5 1.6 3.2 16.7 3.4 16.5 5.5 12.6 3.1 36.8 27.5 26.5 31.0 2.4 3.0 19.7 9.7 56.7 14.5 4.1 2.7 6.9 13.2 9.9 20.4 28.5 2.8 8.0 5.9 0.2 10.8 4.6 40.7 71.4 20.0 15.6 3.0 43.6 30.8 7.6 8.5 5.1 35.5 17.5 8.0 20.8 21.0 2.4 11.5 9.9 0.3 0.0 24.3 1.4 0.2 0.2 0.0 0.0 0.0 0.0 39.2 0.0 33.5 3.4 1.7 33.1 0.0 1.8 0.0 0.0 0.1 0.1 1.0 0.0 4.7 0.0 0.2 1.1 42.6 0.7 2.8 23.0 11.0 0.0 4.2 0.0 0.9 0.8 0.0 4.2 0.1 29.8 1.6 0.0 0.0 4.9 0.2 16.2 0.7 0.0 9.4 1.2 17.4 2.9 0.0 24.8 21.7 0.1 0.6 3.2 0.0 0.0 0.0 0.0 2.0 5.8 0.8 0.0 4.1 0.0 0.0 9.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 24.6 2.0 8.7 10.8 0.0 2.0 2.0 1.8 1.6 3.2 2.4 3.0 4.1 2.7 2.8 3.0 8.5 2.4 254.3 22.4 21.4 0.0 2.0 34.3 10.4 9.5 23.3 0.1 3.9 5.3 16.8 1.5 21.3 0.0 0.0 3.2 16.9 0.0 0.0 1.8 0.9 1.9 1.8 200.6 0.0 2.7 0.3 0.2 37.1 46.1 2.6 7.2 7.6 0.2 65.3 0.8 14.9 0.0 0.7 0.4 4.1 32.4 138.1 4.9 130.8 130.9 16.0 1.0 8.1 0.0 0.0 0.0 0.0 9.0 0.0 259.2 2.3 4.5 0.0 0.3 2.5 0.0 6.6 51.4 39.0 0.2 1.0 237.3 98.6 42.4 3.2 2.8 0.1 58.2 TLCD3A "CT120, FAM57A, FLJ22282" ENSG00000167695 "TLC domain containing 3A" Q8TBR7 17 732412-742968 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 71.7" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 20.1;Hofbauer cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.46e-1)" "unprognostic (6.16e-2)" "unprognostic (5.64e-2)" "prognostic favorable (3.53e-6)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (1.32e-3)" "unprognostic (2.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (4.88e-2)" "unprognostic (1.60e-1)" "unprognostic (8.05e-2)" "unprognostic (1.39e-2)" 7.7 3.5 4.5 6.1 4.9 2.4 8.2 9.7 5.8 10.2 9.5 10.7 12.5 7.3 2.6 23.6 7.1 12.3 4.9 4.7 5.7 5.7 3.7 7.1 3.2 4.2 4.6 7.4 9.7 6.1 8.3 8.2 4.9 9.6 10.0 3.8 11.6 10.9 2.8 71.7 8.6 8.5 4.5 2.9 18.4 12.1 5.5 4.7 8.0 2.9 9.2 18.5 15.9 5.2 63.8 39.4 27.5 36.6 35.5 47.1 27.3 53.9 46.1 53.2 59.4 19.2 9.8 14.4 28.3 51.7 17.1 61.3 57.3 44.3 58.9 38.3 53.1 14.8 26.8 46.6 28.1 12.4 20.7 39.6 38.8 24.2 63.5 24.5 37.3 19.6 13.6 1.7 31.2 22.1 5.3 3.7 12.2 40.7 13.7 25.6 10.8 1.4 38.1 48.9 13.2 25.0 25.7 2.5 16.7 18.0 10.3 13.7 29.1 51.9 23.6 60.8 65.3 4.6 13.3 15.2 47.2 23.9 32.1 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.2 0.5 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.1 1.5 0.1 4.5 4.9 9.7 5.8 4.7 5.7 4.2 4.6 4.9 4.5 5.5 5.2 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 20.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 TMEM115 PL6 ENSG00000126062 "Transmembrane protein 115" Q12893 3 50354750-50359521 "Plasma proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006319, HPA015497" Supported Supported "Golgi apparatus" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "CAB006319: AB_425880, HPA015497: AB_1858076" "unprognostic (1.62e-2)" "unprognostic (2.37e-1)" "unprognostic (1.59e-2)" "unprognostic (1.65e-3)" "unprognostic (2.32e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.00e-2)" "unprognostic (6.00e-2)" "unprognostic (2.05e-2)" "unprognostic (1.75e-3)" "unprognostic (2.65e-2)" "prognostic favorable (1.04e-7)" "unprognostic (4.88e-3)" "unprognostic (3.00e-1)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" 29.4 34.3 23.5 12.0 24.4 11.7 28.6 24.6 26.5 25.2 26.9 29.5 23.4 33.3 17.6 27.2 26.3 15.6 31.9 23.3 23.1 28.9 32.3 26.6 11.3 25.7 24.1 25.4 29.9 32.0 20.3 22.8 24.7 30.7 12.8 6.7 29.1 20.6 27.1 42.6 27.1 17.0 23.2 24.3 31.2 17.0 24.4 10.8 34.6 18.2 9.6 28.0 25.6 24.0 26.6 31.9 20.4 33.6 56.9 45.2 26.4 40.3 59.3 50.2 38.3 24.0 30.4 12.9 33.1 53.1 46.2 27.8 24.7 32.7 14.1 23.9 42.9 19.5 27.8 32.9 79.7 21.4 27.2 68.4 41.6 41.5 30.1 43.3 38.6 15.7 21.3 21.7 37.9 24.5 14.8 33.8 36.4 17.4 49.9 7.2 16.3 28.8 38.3 24.7 22.7 48.7 24.5 26.9 34.5 17.8 22.3 22.4 40.4 45.3 22.8 48.1 42.9 32.0 19.9 7.3 41.6 23.3 30.5 52.5 27.9 41.4 26.5 25.1 17.5 18.2 17.5 21.2 23.2 18.5 18.7 18.2 37.9 27.3 24.5 26.1 24.1 23.8 23.5 24.4 24.6 26.5 23.3 23.1 25.7 24.1 24.7 23.2 24.4 24.0 24.0 16.0 12.4 4.2 14.3 30.2 19.7 26.1 29.6 17.1 25.3 24.9 7.0 25.8 15.8 11.0 6.2 58.8 15.9 39.9 3.9 44.7 1.1 17.9 17.2 22.9 15.7 18.5 2.9 26.5 42.2 31.5 20.4 16.3 11.4 23.6 26.0 19.5 36.3 18.5 3.7 26.6 28.5 11.4 12.4 1.2 29.2 15.5 10.6 2.8 20.4 25.7 13.4 6.6 4.4 35.6 32.5 25.2 18.8 33.8 43.9 26.9 14.3 15.1 26.3 19.3 26.5 17.0 8.0 17.5 34.9 92.8 14.3 36.4 24.9 25.6 TMPRSS13 "MSPL, MSPS, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900641-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7;skin 1: 41.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.9;Extravillous trophoblasts: 21.2;Glandular and luminal cells: 10.9;Ionocytes: 16.2;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.8;BEWO: 29.9;MCF7: 27.0;SK-BR-3: 42.8;T-47d: 43.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.08e-3)" "unprognostic (5.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (5.61e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-6)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.44e-1)" 0.3 0.4 0.2 0.7 0.2 0.6 7.1 0.0 0.7 6.7 0.0 0.4 0.3 0.6 0.6 15.7 0.3 0.4 0.1 0.9 0.0 2.6 0.2 3.9 1.2 0.0 0.0 0.1 2.5 0.0 0.3 2.9 0.0 1.4 0.4 0.0 11.0 0.1 0.2 41.0 0.8 0.2 0.0 1.5 0.2 0.4 0.0 0.9 6.6 0.0 4.8 0.5 9.3 0.1 13.8 0.1 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 10.2 0.1 0.7 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.5 0.7 0.0 27.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 1.4 0.0 4.0 0.4 0.1 0.0 42.8 0.6 1.7 43.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.2 0.2 0.2 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.6 0.0 0.2 1.7 4.6 1.7 1.2 0.0 7.4 4.6 1.4 7.2 5.3 0.0 0.0 15.9 0.2 0.3 0.0 8.3 0.3 2.4 1.3 0.2 0.0 0.0 0.2 1.2 21.2 0.3 0.5 10.9 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.5 16.2 1.2 1.9 0.8 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 5.7 3.9 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 5.2 8.0 19.4 0.4 0.5 0.8 9.0 TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" 5.9 4.4 3.6 3.8 3.8 1.7 6.7 5.8 4.7 5.6 2.1 4.5 5.4 6.4 5.2 9.1 3.9 5.7 3.8 3.9 4.6 8.1 9.0 5.2 2.9 3.4 3.9 5.3 3.2 6.2 2.8 10.2 4.1 7.4 4.7 7.9 3.8 6.3 1.7 12.5 4.4 9.2 3.2 3.9 3.8 4.1 3.6 4.0 6.3 4.3 4.5 6.8 4.7 4.1 13.2 14.0 12.6 11.9 28.8 25.4 22.5 28.1 26.6 15.8 16.9 20.3 9.2 4.1 5.0 25.8 9.6 28.9 13.5 22.4 26.5 2.4 10.2 4.0 9.5 9.3 15.0 4.3 2.5 21.7 12.0 30.5 12.0 16.2 24.9 3.4 8.9 1.4 17.8 7.9 3.0 5.5 9.7 5.0 7.3 2.6 27.4 4.1 13.7 21.3 10.7 10.6 22.8 16.1 7.3 13.3 25.9 4.3 26.4 21.8 12.0 19.4 13.7 4.5 6.3 4.7 6.8 5.0 16.5 7.4 1.3 2.3 1.8 1.1 2.2 2.3 2.0 1.4 0.9 1.8 2.4 2.0 1.3 1.2 1.6 0.9 1.7 0.7 3.6 3.8 5.8 4.7 3.9 4.6 3.4 3.9 4.1 3.2 3.6 4.1 15.9 12.8 8.2 19.6 6.9 34.2 24.4 29.1 24.5 12.5 11.4 8.1 11.1 5.7 20.0 7.3 27.1 29.6 3.5 6.7 3.9 14.5 26.8 23.7 22.2 16.9 3.6 9.5 51.6 10.8 18.2 23.8 8.6 21.9 9.5 12.4 15.7 19.2 8.2 13.5 46.8 5.9 75.3 5.9 6.0 18.2 20.2 3.7 8.8 20.6 2.8 8.3 2.1 28.1 42.4 12.4 4.9 19.5 4.6 18.0 7.3 13.9 34.9 23.4 19.7 17.1 22.3 12.0 8.7 32.6 40.5 17.8 5.2 14.1 7.1 14.4 TNFRSF18 "AITR, CD357, GITR" ENSG00000186891 "TNF receptor superfamily member 18" Q9Y5U5 1 1203508-1206592 "CD markers, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 189.0;dendritic cells: 72.2;Langerhans cells: 86.4;Melanocytes: 49.8;Plasma cells: 55.3;Suprabasal keratinocytes: 150.6;T-cells: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cell: 184.5;T-reg: 71.8" "Group enriched" "Detected in many" 11 "NK-cells: 184.5;T-cells: 71.8" "Group enriched" "Detected in some" 12 "RPMI-8226: 225.6;SCLC-21H: 152.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008025 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA008025: AB_1849696" "unprognostic (1.20e-3)" "unprognostic (4.61e-2)" "unprognostic (4.59e-2)" "prognostic favorable (7.72e-6)" "unprognostic (2.73e-4)" "prognostic favorable (4.12e-4)" "unprognostic (3.43e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.40e-11)" "unprognostic (1.02e-3)" "unprognostic (2.39e-1)" "unprognostic (3.74e-1)" "unprognostic (2.08e-1)" 1.9 0.6 1.1 7.3 1.3 2.9 2.4 2.5 3.1 11.1 0.7 6.0 7.2 1.4 0.0 6.3 1.4 0.9 0.5 1.0 0.6 2.8 0.9 4.6 5.5 1.3 0.6 0.3 0.3 9.4 4.9 0.3 1.3 2.8 1.5 0.0 5.6 0.6 0.8 38.5 7.1 0.3 0.6 9.0 5.2 0.9 0.9 1.9 1.4 0.0 3.8 2.0 3.3 1.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 1.2 0.1 0.5 16.1 0.1 0.1 225.6 0.3 0.0 152.8 0.2 0.0 0.6 0.0 0.0 8.2 0.1 0.0 0.0 0.3 0.2 0.0 0.9 0.3 0.2 0.6 0.1 0.0 0.2 0.2 0.0 6.8 0.1 12.6 4.6 28.9 4.4 0.1 11.5 0.9 1.5 0.8 184.5 0.1 0.3 71.8 6.7 1.1 1.3 2.5 3.1 1.0 0.6 1.3 0.6 1.3 0.6 0.9 1.2 11.2 0.0 1.3 0.3 23.5 189.0 12.5 15.5 16.5 0.0 5.0 3.0 2.9 0.0 3.2 0.0 0.0 0.0 72.2 0.3 0.0 0.8 0.0 1.2 1.2 4.1 3.5 0.0 2.0 0.6 1.3 4.7 1.1 2.9 45.7 0.0 0.7 0.0 0.8 0.0 0.3 0.2 20.3 0.3 86.4 0.0 0.0 5.4 49.8 0.0 12.7 0.0 21.6 0.5 0.3 0.4 0.0 0.0 55.3 10.1 0.1 0.1 0.8 0.0 0.0 6.2 2.2 0.0 0.0 0.3 150.6 0.0 75.7 0.0 0.8 7.0 TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Uncertain "Plasma membrane" NA NA 180000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA037929: AB_10672613, HPA037930: AB_2675745" "unprognostic (7.31e-2)" "unprognostic (1.66e-2)" "unprognostic (5.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.13e-1)" "unprognostic (9.17e-2)" "unprognostic (2.47e-2)" "unprognostic (7.90e-2)" "unprognostic (4.27e-1)" "unprognostic (2.67e-2)" "unprognostic (4.22e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (2.46e-1)" "unprognostic (2.31e-2)" "unprognostic (2.41e-1)" "unprognostic (3.07e-1)" 62.7 27.3 11.8 17.3 10.2 3.3 41.9 4.6 9.4 43.3 18.0 23.6 28.8 40.3 30.3 55.4 35.3 28.1 23.3 11.3 9.2 14.7 31.6 40.3 6.6 9.6 8.8 32.2 30.9 18.9 17.1 29.5 7.2 33.6 16.2 3.3 44.2 40.2 67.2 83.0 26.6 29.4 4.9 18.1 52.8 10.1 11.0 22.3 25.0 29.9 14.3 38.5 45.6 6.7 89.5 58.7 41.2 33.6 127.8 97.1 31.0 61.5 113.8 46.3 42.5 26.1 59.5 2.0 38.5 101.2 49.6 151.7 31.4 105.3 30.1 34.2 10.4 11.5 38.2 12.2 86.6 14.4 4.3 96.8 123.5 70.9 54.6 57.5 60.0 12.4 13.2 9.3 65.3 45.4 11.0 14.7 45.8 46.5 45.9 16.9 57.2 25.9 53.5 116.6 14.6 22.6 81.5 121.5 44.3 29.0 182.2 11.9 115.1 47.3 45.8 56.6 35.2 15.0 4.1 11.3 107.0 4.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.8 10.2 4.6 9.4 11.3 9.2 9.6 8.8 7.2 4.9 11.0 6.7 38.1 12.8 35.4 12.7 1.9 83.6 28.0 61.9 40.9 4.8 24.8 23.9 7.9 38.6 39.0 44.1 2.1 16.8 1.3 27.3 0.0 31.8 1.8 18.5 25.4 25.9 18.0 7.4 7.2 22.3 3.2 31.2 49.5 38.4 2.5 3.7 19.6 46.0 3.9 8.4 4.8 25.8 18.3 1.5 25.4 2.9 48.1 3.8 17.8 1.9 0.7 4.0 0.0 4.5 2.4 38.8 14.3 49.2 0.6 41.2 18.2 2.4 15.4 1.3 32.9 41.2 26.9 1.5 3.0 68.9 88.2 24.5 2.3 23.4 14.5 36.8 TNS4 CTEN ENSG00000131746 "Tensin 4" Q8IZW8 17 40475828-40501623 "Predicted intracellular proteins" Apoptosis Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 205.0;vagina: 74.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 133.4;Basal prostatic cells: 117.7;Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 77.4;Suprabasal keratinocytes: 65.5;Urothelial cells: 50.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 77.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 136.2;HBEC3-KT: 613.4;hTCEpi: 435.3;hTERT-HME1: 138.8;OE19: 125.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (4.16e-2)" "unprognostic (9.83e-2)" "unprognostic (1.01e-1)" "unprognostic (3.40e-2)" "unprognostic (3.68e-4)" "unprognostic (7.88e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.89e-1)" "unprognostic (8.02e-3)" "unprognostic (2.01e-3)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (3.72e-1)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (7.08e-2)" 0.9 0.1 0.0 1.1 0.0 0.1 16.5 0.0 0.0 28.6 0.1 3.2 0.8 0.7 3.5 46.1 0.9 0.3 0.1 0.0 0.0 1.0 0.1 0.5 0.2 0.0 0.0 0.1 0.1 0.0 0.9 9.7 0.0 35.6 5.9 0.0 58.8 19.6 0.2 205.0 0.8 0.1 0.0 0.0 1.8 0.0 0.0 1.4 14.3 0.0 6.9 14.8 74.7 0.2 7.7 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 18.6 0.1 3.9 0.0 0.0 136.2 0.0 613.4 0.0 0.0 0.0 0.0 57.5 9.3 0.0 0.0 0.4 0.0 435.3 0.0 138.8 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.2 0.2 0.0 125.9 70.2 0.0 0.0 0.0 0.0 32.3 0.0 0.0 79.4 14.4 0.0 0.7 16.0 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.0 0.0 133.4 117.7 39.8 287.4 0.0 1.6 25.5 0.9 0.0 18.2 0.0 0.0 4.7 0.5 7.5 1.9 0.2 0.0 4.6 0.7 1.3 0.0 0.0 0.1 0.2 0.5 1.0 2.0 3.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 3.5 2.0 0.0 8.8 0.0 0.0 1.1 5.4 0.0 0.6 0.0 0.0 0.0 0.1 25.2 0.3 0.0 0.0 18.9 0.1 0.0 7.3 0.0 0.0 0.1 1.6 0.0 0.0 77.4 65.5 4.4 2.1 0.0 2.6 50.2 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TPRA1 "FLJ32197, GPR175, TMEM227, TPRA40" ENSG00000163870 "Transmembrane protein adipocyte associated 1" Q86W33 3 127571232-127598267 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 179.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019784 Approved Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA019784: AB_2670266" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-3)" "unprognostic (1.66e-2)" "unprognostic (6.91e-3)" "unprognostic (9.74e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.46e-1)" "unprognostic (2.32e-1)" "unprognostic (1.91e-1)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (2.02e-2)" "unprognostic (1.73e-2)" "unprognostic (4.42e-2)" "unprognostic (2.09e-1)" "unprognostic (4.28e-2)" 23.9 29.7 22.4 11.7 23.3 26.5 24.5 23.4 26.2 35.8 25.9 25.8 16.9 28.8 12.5 26.4 28.1 16.5 24.7 22.3 23.3 26.8 37.0 24.9 13.9 22.9 23.4 27.8 26.7 29.0 21.7 20.8 23.0 28.8 11.3 8.0 26.4 16.2 26.8 42.9 21.2 17.2 22.7 25.0 25.8 16.3 24.2 11.5 27.0 19.8 13.0 28.5 28.8 22.7 40.0 31.2 12.9 27.3 51.4 28.6 42.1 20.5 34.2 24.7 22.2 22.1 30.9 36.7 37.6 38.4 77.2 43.6 22.6 34.8 12.9 20.0 15.0 21.4 46.0 20.7 56.6 13.3 44.7 28.8 28.8 16.4 42.8 51.2 18.0 24.5 14.0 36.7 30.4 39.8 18.5 43.4 19.3 25.5 23.4 31.9 17.0 37.0 29.6 19.1 24.6 9.5 37.7 57.7 35.1 10.4 27.3 42.3 28.7 29.6 13.1 60.0 13.2 25.0 21.0 34.4 31.9 38.8 22.4 3.8 12.9 11.5 6.4 9.4 8.6 6.6 7.4 9.5 12.7 6.4 5.6 6.8 7.0 6.6 8.4 9.7 7.2 6.5 22.4 23.3 23.4 26.2 22.3 23.3 22.9 23.4 23.0 22.7 24.2 22.7 15.7 22.4 7.0 13.1 11.7 50.0 20.5 18.8 24.5 7.8 16.3 17.9 11.8 11.5 16.5 25.8 4.2 56.9 8.4 18.2 5.9 29.1 2.7 23.5 18.0 22.8 17.4 46.5 9.3 19.6 43.3 22.9 17.9 27.5 17.8 13.9 21.8 21.7 32.9 5.0 9.7 18.7 18.3 16.0 179.7 2.4 33.5 32.0 30.2 5.6 52.3 11.2 20.6 6.6 8.1 31.4 17.6 19.5 17.9 37.5 37.5 13.1 12.4 8.9 13.1 13.2 18.3 8.4 17.9 19.1 54.4 68.1 12.6 12.7 20.7 23.5 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240379-1242554 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "granulocytes: 5873.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 893 "basophil: 89.3" "Lineage enriched" "Detected in single" 893 "granulocytes: 89.3" "Cell line enriched" "Detected in some" 166 "HMC-1: 3813.2" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB016369: AB_628406, CAB022175: , HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favorable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 96.6 2.9 0.3 23.6 0.5 2.4 47.2 0.3 0.9 53.7 0.9 83.0 71.6 73.3 6.0 64.3 26.6 129.7 14.7 0.4 0.4 13.9 12.2 128.5 21.3 0.4 0.3 3.2 18.9 2.3 3.5 1.2 0.6 65.9 34.6 0.0 60.2 22.5 10.1 122.7 148.7 17.9 0.4 5.9 104.0 8.9 0.4 14.2 4.7 13.0 13.2 113.5 52.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 1.3 3813.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.3 2.1 6.1 0.5 0.4 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.1 1.1 0.0 0.0 2.8 22.9 2.0 89.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.5 0.3 0.9 0.4 0.4 0.4 0.3 0.6 0.4 0.4 0.3 0.0 25.6 135.5 0.0 2.9 18.6 5.1 0.0 1.2 0.0 0.9 0.1 0.3 0.0 8.1 0.0 0.0 0.0 0.2 0.9 0.0 1.2 0.3 0.0 0.0 4.1 0.0 3.8 0.0 0.0 0.2 7.6 0.5 0.0 5873.9 0.0 0.0 0.3 5.2 0.0 0.0 0.0 0.0 0.3 25.6 0.2 0.0 7.7 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 11.7 4.0 0.4 0.1 5.1 0.0 0.0 0.3 3.2 0.0 0.1 0.1 9.9 0.3 440.9 0.0 0.5 5.6 TPSB2 ENSG00000197253 "Tryptase beta 2" P20231 16 1227272-1230184 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 25 "granulocytes: 8966.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 50 "basophil: 5.0" "Lineage enriched" "Detected in single" 50 "granulocytes: 5.0" "Cell line enriched" "Detected in some" 7 "HMC-1: 297.5" "HPA049153, HPA049554" Supported "Secreted to blood" NA NA 16000000 "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 95.1 2.5 0.3 20.2 0.6 4.3 47.8 0.3 0.9 53.2 1.0 77.8 35.5 71.8 9.8 64.6 30.4 103.9 15.0 0.5 0.5 15.5 12.2 127.8 26.2 0.5 0.4 3.5 18.9 1.5 3.9 1.3 0.5 67.0 19.8 0.0 64.5 13.3 10.0 122.5 146.1 22.0 0.5 5.2 102.1 9.9 0.5 4.9 4.7 10.4 9.9 118.6 53.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.2 0.4 297.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 4.7 0.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.7 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.9 0.5 0.5 0.5 0.4 0.5 0.5 0.5 0.3 0.1 38.5 275.3 0.0 2.8 0.0 4.4 0.0 0.0 0.0 1.5 0.0 1.5 0.0 16.7 0.0 0.0 0.1 0.6 0.7 0.0 2.4 0.6 0.0 0.0 3.2 0.0 18.9 0.0 0.0 0.2 6.0 2.0 0.0 8966.1 0.0 0.0 0.0 3.8 0.0 0.1 0.7 0.0 0.0 0.0 1.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.8 5.4 0.7 0.1 3.6 0.0 0.0 0.4 1.1 0.0 0.7 0.0 0.0 0.1 345.1 0.0 1.0 6.1 TRMT44 "C4orf23, FLJ35725, METTL19, TRM44" ENSG00000155275 "TRNA methyltransferase 44 homolog" Q8IYL2 4 8436140-8493531 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045461 Uncertain Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA045461: AB_10961276" "unprognostic (1.50e-1)" "unprognostic (1.65e-3)" "unprognostic (3.47e-1)" "unprognostic (1.01e-2)" "unprognostic (2.06e-1)" "unprognostic (1.34e-2)" "unprognostic (1.75e-1)" "unprognostic (1.78e-2)" "unprognostic (3.46e-1)" "unprognostic (8.13e-2)" "unprognostic (3.44e-3)" "unprognostic (2.69e-3)" "unprognostic (1.49e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (6.76e-2)" "unprognostic (8.34e-3)" 5.8 3.5 2.0 3.9 2.5 7.1 6.9 2.6 2.8 5.1 0.7 4.9 3.6 6.2 4.4 6.6 5.4 3.4 4.6 2.2 0.9 3.2 4.2 4.2 5.0 0.9 0.6 7.6 4.5 4.2 3.2 4.9 1.2 4.8 3.2 3.7 5.5 3.8 5.9 9.0 3.6 4.4 0.6 4.0 5.3 4.9 1.3 3.7 4.5 2.6 5.2 5.0 5.6 2.6 5.2 5.1 6.4 7.5 6.5 6.3 15.2 5.9 4.2 7.6 6.7 6.8 7.0 6.9 3.1 2.3 6.4 4.1 9.3 5.4 6.7 3.7 5.9 6.9 8.9 5.1 6.0 11.4 4.9 3.9 7.7 5.8 6.3 6.4 8.1 4.8 10.2 7.2 5.0 3.2 9.5 8.3 7.4 6.5 8.5 6.9 6.9 4.9 6.6 6.0 6.9 4.7 3.8 3.4 5.5 7.2 2.9 4.7 5.2 4.6 2.5 4.4 9.3 8.4 6.0 6.2 5.1 10.7 4.7 0.1 0.3 0.0 0.6 0.3 0.3 0.2 0.5 0.6 0.5 0.5 0.7 0.2 0.0 0.2 0.6 0.4 0.0 0.1 2.0 2.5 2.6 2.8 2.2 0.9 0.9 0.6 1.2 0.6 1.3 2.6 4.4 9.6 7.3 12.7 4.9 6.8 4.2 3.1 2.8 7.8 6.8 5.1 3.3 7.2 3.2 7.3 25.0 10.2 4.1 2.6 5.9 5.0 3.8 16.2 13.0 4.7 1.8 1.7 21.3 4.5 6.2 7.5 14.8 25.6 5.1 18.8 5.0 3.8 4.6 3.3 18.4 2.0 2.0 3.1 2.4 2.8 5.9 3.7 1.8 8.4 4.1 2.6 3.1 8.5 12.3 4.5 7.2 3.8 5.3 5.3 3.0 2.7 8.1 10.8 0.0 6.3 6.5 9.2 5.8 8.2 5.8 16.3 5.2 4.8 3.8 7.6 TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.2;skin 1: 4.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.7;Plasma cells: 15.9;Proximal enterocytes: 26.1;Suprabasal keratinocytes: 24.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.3;BEWO: 5.0;CACO-2: 3.1;RH-30: 11.9;T-47d: 5.2;U-266/70: 3.1;U-266/84: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: AB_2686149" "unprognostic (1.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.22e-2)" "unprognostic (3.92e-4)" "unprognostic (4.87e-3)" "unprognostic (2.96e-2)" "unprognostic (6.66e-2)" "unprognostic (4.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (4.88e-2)" "unprognostic (3.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (2.93e-2)" 0.1 0.0 1.1 0.5 1.1 0.5 0.2 0.1 1.1 0.3 0.0 0.9 2.0 0.0 0.1 0.2 0.0 0.1 0.0 0.6 0.3 0.0 0.6 0.1 0.3 0.4 0.3 0.2 0.0 0.1 0.3 0.2 0.4 0.1 1.7 0.2 0.1 0.0 1.5 4.8 5.2 0.1 0.1 0.2 0.9 0.4 0.9 0.0 0.0 0.5 0.5 0.2 0.3 1.8 3.3 0.0 0.3 0.0 0.2 0.3 5.0 0.1 0.0 0.0 0.0 3.1 0.8 0.1 1.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.2 0.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.2 0.4 0.1 11.9 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 5.2 0.1 0.0 0.0 0.1 0.1 0.0 3.1 2.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 1.1 0.1 1.1 0.6 0.3 0.4 0.3 0.4 0.1 0.9 1.8 0.2 0.0 2.5 2.9 5.8 18.7 3.9 0.2 10.2 1.2 0.9 0.5 3.5 1.5 0.2 0.0 0.0 0.3 2.6 8.9 1.9 0.0 0.3 0.7 0.9 1.6 0.0 0.0 1.6 0.0 0.9 3.7 6.1 0.9 0.0 1.1 0.0 0.3 0.3 5.0 0.6 2.7 0.0 0.0 3.8 0.4 3.1 0.8 7.2 0.0 0.1 2.2 3.1 0.5 2.3 1.2 2.5 3.4 15.9 5.9 26.1 2.3 0.2 1.0 0.0 6.9 1.8 0.0 1.5 2.9 24.6 0.5 1.8 2.8 0.9 3.7 TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 111.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.2;Glandular and luminal cells: 76.8;Suprabasal keratinocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" 5.6 6.8 4.7 2.8 4.2 6.7 10.1 5.0 5.3 25.4 3.4 11.6 7.5 5.3 6.3 48.1 5.1 5.9 4.9 3.8 5.9 14.1 7.0 8.4 0.9 4.0 4.0 7.4 17.2 11.4 7.2 13.3 5.2 9.6 13.0 2.1 18.3 9.2 2.5 111.5 10.8 6.2 3.3 1.5 12.8 5.4 6.2 2.2 5.7 2.7 6.2 12.4 26.8 3.5 40.7 13.7 10.0 11.5 2.3 1.9 63.1 10.7 9.5 41.3 39.6 43.6 31.5 3.5 64.6 12.5 19.5 46.4 17.6 16.2 30.1 27.0 8.7 2.2 23.0 6.7 32.2 0.8 4.7 6.5 18.9 32.5 71.6 24.5 3.4 5.0 3.6 26.8 12.8 16.8 2.0 0.5 11.7 29.6 11.4 0.1 28.1 14.2 34.7 61.8 19.5 8.0 68.2 45.8 8.0 29.4 36.5 2.1 8.6 7.4 51.7 46.2 71.7 6.6 13.7 0.5 6.3 0.9 4.7 5.2 0.6 0.7 0.3 0.1 0.7 0.6 1.0 0.5 0.9 0.2 0.8 0.3 2.5 0.1 0.3 0.1 3.5 0.5 4.7 4.2 5.0 5.3 3.8 5.9 4.0 4.0 5.2 3.3 6.2 3.5 2.1 25.6 2.0 1.6 3.8 69.2 35.2 14.7 35.9 2.5 28.8 20.2 9.8 8.6 19.0 14.7 0.0 28.1 6.6 59.5 13.7 18.2 2.7 43.2 8.9 2.7 32.2 2.7 4.4 15.2 13.9 7.0 46.9 76.8 4.5 9.0 1.1 10.5 4.0 0.0 9.3 39.1 20.3 0.0 12.7 3.2 2.5 6.5 8.8 1.0 2.0 2.1 0.0 8.5 1.8 47.4 34.6 5.3 7.7 21.7 15.4 11.2 15.9 0.5 6.6 4.1 5.5 0.6 3.5 39.6 66.5 56.8 5.8 10.9 35.7 35.6 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074510-19210266 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 271.0;Suprabasal keratinocytes: 252.9;Urothelial cells: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA 15000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 56.2 62.8 48.2 23.0 46.0 79.8 49.8 38.7 48.4 57.4 47.6 69.6 20.9 61.7 35.7 55.4 52.3 29.6 58.7 45.8 46.0 74.7 82.7 71.9 25.7 51.5 46.4 75.3 53.5 35.5 70.7 27.5 54.9 67.2 22.7 44.6 48.0 27.0 129.1 161.9 59.7 26.0 35.2 62.8 70.6 105.3 45.9 34.6 56.5 45.0 25.7 90.0 59.2 44.7 61.4 60.7 53.5 39.7 97.6 50.0 46.2 46.5 48.8 49.5 44.7 97.2 51.3 36.6 42.3 61.7 43.3 40.8 42.3 46.3 46.0 30.6 37.5 83.8 63.3 64.1 68.6 51.9 53.4 45.0 57.9 100.8 96.3 48.1 54.9 63.7 58.5 32.9 47.6 43.6 24.7 62.9 43.5 124.3 33.6 34.0 41.7 31.0 44.7 35.2 37.7 37.4 55.0 31.1 39.9 48.6 21.7 40.4 85.9 57.4 36.1 69.0 52.8 38.8 25.2 41.5 39.3 79.3 50.3 39.8 28.7 4.7 4.9 5.9 4.2 7.4 4.4 2.9 14.2 4.0 3.9 3.7 15.4 4.4 2.1 6.5 3.4 8.3 48.2 46.0 38.7 48.4 45.8 46.0 51.5 46.4 54.9 35.2 45.9 44.7 28.1 35.3 37.6 85.5 30.3 271.0 124.6 28.9 28.5 57.5 22.1 23.9 19.1 37.1 30.4 31.3 152.2 24.7 34.2 31.6 13.7 41.3 21.4 39.8 32.0 30.8 17.5 48.4 58.9 40.9 17.0 32.2 44.9 50.4 19.6 32.9 31.1 94.1 63.2 79.1 61.8 29.2 12.2 43.0 48.7 28.7 30.7 46.4 49.8 34.7 64.4 28.8 21.6 51.8 44.5 61.0 16.7 35.7 26.4 59.1 57.9 135.6 39.1 48.5 19.7 28.3 30.1 44.8 21.0 28.0 252.9 33.9 32.7 34.5 20.1 236.5 UCN2 "SRP, UCN-II, UCNI, URP" ENSG00000145040 "Urocortin 2" Q96RP3 3 48561718-48563781 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 13.1;vagina: 4.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.9;Basal respiratory cells: 1.4" "Cancer enriched" "Detected in many" 5 "melanoma: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 18.8;hTCEpi: 27.3;hTEC/SVTERT24-B: 21.5;SiHa: 19.1;U-251 MG: 20.7;WM-115: 55.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA066841 Uncertain Approved Vesicles "Secreted to blood" NA NA 98600 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA066841: AB_2685735" "unprognostic (7.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.80e-2)" "unprognostic (1.96e-2)" "unprognostic (2.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.92e-3)" "unprognostic (2.02e-3)" "unprognostic (1.62e-1)" "unprognostic (2.93e-3)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (3.34e-14)" "unprognostic (4.39e-2)" "unprognostic (2.75e-1)" "unprognostic (1.36e-1)" "unprognostic (2.88e-2)" 0.1 0.0 0.2 0.3 0.1 0.1 0.4 0.3 0.4 2.3 0.1 0.2 0.1 1.2 0.7 3.4 0.2 0.4 0.3 0.2 0.4 1.4 0.0 0.2 0.0 0.3 0.3 0.2 0.0 0.0 0.3 0.2 0.3 3.1 0.0 0.0 1.6 0.4 0.3 13.1 0.2 0.2 0.2 0.7 0.2 1.4 0.3 0.0 0.0 0.0 0.1 0.5 4.5 0.2 0.0 3.1 0.5 0.1 1.8 1.1 2.6 9.7 12.1 5.9 4.4 0.0 0.0 0.0 0.4 2.3 7.0 1.9 0.0 11.6 3.2 9.2 0.2 0.2 18.8 1.5 2.0 0.0 0.5 1.3 27.3 21.5 4.3 4.1 0.0 0.2 0.0 0.2 0.9 0.0 0.0 1.8 0.8 0.0 0.2 0.2 0.3 0.0 1.8 0.0 0.0 0.0 19.1 0.0 14.5 1.7 0.3 0.4 0.0 2.6 1.8 0.3 20.7 0.1 0.3 0.0 8.8 0.1 55.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.2 0.4 0.3 0.3 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 UEVLD "Attp, UEV3" ENSG00000151116 "UEV and lactate/malate dehyrogenase domains" Q8IX04 11 18529609-18588747 "Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047134 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA047134: AB_10960698" "unprognostic (1.05e-1)" "unprognostic (6.76e-2)" "prognostic favorable (7.07e-4)" "unprognostic (5.94e-3)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.38e-3)" "unprognostic (9.08e-3)" "unprognostic (9.81e-2)" "unprognostic (2.87e-2)" "unprognostic (1.26e-3)" "unprognostic (1.71e-2)" "unprognostic (1.61e-3)" "unprognostic (2.65e-1)" "unprognostic (3.22e-1)" "unprognostic (8.23e-2)" "unprognostic (3.39e-1)" 10.1 8.4 5.3 8.8 7.9 4.5 11.8 6.5 6.7 11.5 6.3 13.4 11.1 8.8 8.7 10.7 8.8 9.4 9.2 5.7 6.4 12.3 9.0 9.0 7.0 8.1 7.1 8.0 7.2 9.9 4.2 9.4 8.5 10.4 14.1 9.7 7.5 9.5 11.0 14.8 10.0 11.0 6.6 6.9 9.8 5.3 7.0 7.6 10.9 10.5 8.6 10.2 6.9 11.1 16.2 19.6 8.9 8.6 28.2 25.1 8.3 17.5 24.3 22.7 21.6 8.1 4.6 5.0 9.4 20.7 19.8 24.8 8.2 18.1 25.8 14.6 10.7 7.5 8.8 9.1 12.7 11.5 10.4 17.4 18.3 11.2 15.5 15.9 21.2 0.4 5.7 4.7 29.3 12.3 0.3 3.7 2.4 24.9 19.8 1.8 20.7 6.2 26.9 25.4 3.7 7.9 19.1 23.8 15.1 11.0 19.1 6.8 16.2 20.7 11.1 34.0 17.2 0.9 11.3 1.1 17.7 8.7 21.3 4.6 4.9 3.1 4.2 5.1 4.0 2.6 3.1 3.5 3.4 2.7 1.8 2.6 6.5 5.2 4.2 4.2 2.3 2.4 5.3 7.9 6.5 6.7 5.7 6.4 8.1 7.1 8.5 6.6 7.0 11.1 10.3 16.0 19.3 18.9 4.5 6.2 6.3 9.9 8.6 9.3 11.2 6.3 10.1 5.7 12.4 23.9 10.4 8.4 9.4 27.3 3.9 10.8 3.3 13.6 12.4 11.6 9.1 4.8 14.7 13.3 7.4 8.7 10.7 12.9 6.3 11.6 13.6 13.5 12.5 15.2 14.4 15.4 18.3 18.6 10.3 2.0 8.1 11.0 7.2 20.6 11.9 13.3 11.3 25.1 34.3 14.5 10.3 18.4 3.4 8.3 12.8 12.8 23.9 11.1 13.1 10.2 8.7 7.1 7.2 10.1 9.2 7.7 6.6 11.7 15.7 7.6 VAT1 "FLJ20230, VATI" ENSG00000108828 "Vesicle amine transport 1" Q99536 17 43014607-43025123 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 133.2;Hofbauer cells: 146.4;Melanocytes: 122.7" "Cancer enhanced" "Detected in all" "melanoma: 295.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 104.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 104.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 680.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045170 Uncertain NA NA 2700000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA045170: AB_10964166" "unprognostic (2.22e-2)" "unprognostic (4.41e-3)" "unprognostic (6.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (9.67e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.16e-2)" "unprognostic (5.56e-2)" "unprognostic (1.86e-2)" "unprognostic (1.17e-3)" "unprognostic (2.38e-1)" "prognostic favorable (5.89e-4)" "unprognostic (1.71e-2)" "unprognostic (3.66e-2)" "unprognostic (1.07e-1)" "unprognostic (3.36e-2)" 180.4 251.5 53.6 32.1 57.6 86.5 137.5 55.3 67.3 160.8 54.8 97.5 25.7 121.4 65.0 132.6 78.4 85.6 74.7 47.3 129.9 70.5 44.5 111.7 29.0 88.4 132.3 184.8 67.2 54.7 103.7 83.9 173.9 64.9 32.9 7.6 86.3 52.2 29.2 194.3 65.1 94.2 60.5 40.3 56.1 79.2 93.3 63.7 68.3 45.8 33.7 109.5 126.3 77.3 38.9 225.0 53.6 119.0 556.9 435.5 75.5 94.2 282.1 89.7 167.1 139.7 83.2 7.7 128.8 395.8 283.7 58.9 94.1 81.6 82.7 14.4 127.6 36.2 107.3 279.5 357.7 177.6 271.5 234.3 119.2 154.0 71.2 203.8 428.9 230.5 77.3 12.1 227.3 37.2 262.2 76.6 68.1 111.6 106.2 37.3 66.1 19.4 102.2 76.6 50.0 94.6 51.3 29.5 680.8 217.9 82.5 99.4 431.7 199.9 92.5 226.2 22.9 19.4 30.2 14.3 203.1 132.0 31.4 104.0 16.6 24.9 13.1 7.9 15.3 19.9 18.5 13.6 8.4 19.5 16.8 10.4 5.1 11.1 9.2 4.1 13.4 19.0 53.6 57.6 55.3 67.3 47.3 129.9 88.4 132.3 173.9 60.5 93.3 77.3 133.2 22.4 13.9 1.0 17.2 28.4 14.2 17.9 34.1 1.1 29.5 30.2 31.6 17.2 10.7 23.9 4.2 6.5 6.5 9.2 17.6 99.7 27.5 14.2 32.5 71.0 15.1 12.6 2.3 43.4 45.1 91.4 8.2 32.6 77.2 93.8 73.9 15.8 146.4 5.0 2.4 4.1 4.1 40.0 32.4 45.2 51.9 43.9 122.7 6.5 16.1 4.2 3.1 3.5 4.1 49.6 10.4 58.6 19.6 25.5 36.5 60.1 12.6 1.8 13.1 19.4 39.1 12.8 15.5 35.1 33.5 11.1 12.6 31.2 4.7 21.8 VPS36 "C13orf9, CGI-145, Eap45" ENSG00000136100 "Vacuolar protein sorting 36 homolog" Q86VN1 13 52412602-52450634 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039734, HPA043947" Approved Supported "Vesicles,Lysosomes,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Lysosomes" "Plasma membrane, Cell Junctions" "HPA039734: AB_2676652, HPA043947: AB_2678744" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-1)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" "unprognostic (3.96e-3)" "unprognostic (1.19e-2)" "unprognostic (9.37e-2)" "unprognostic (5.57e-2)" "prognostic favorable (9.91e-6)" "unprognostic (6.47e-3)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (9.83e-2)" 17.1 15.1 10.1 16.8 11.5 8.6 26.1 14.0 16.3 20.0 9.6 24.5 27.6 18.7 12.2 23.7 16.8 16.6 24.0 11.8 10.1 25.4 23.6 19.9 19.5 12.4 11.0 17.9 17.9 23.3 11.0 25.0 12.8 21.8 27.5 43.1 25.2 18.3 23.4 51.1 27.7 20.7 9.9 24.1 18.1 4.0 12.1 22.3 22.5 26.2 20.7 18.9 21.3 12.1 7.3 11.8 20.4 13.5 21.1 29.3 17.8 16.7 12.5 16.1 9.6 14.3 22.9 25.5 8.6 23.8 10.6 20.1 16.6 19.7 18.0 19.3 16.0 30.2 18.7 12.8 25.3 40.2 31.4 20.5 37.9 11.2 18.0 18.0 16.6 33.6 22.7 21.8 31.8 9.6 30.4 40.6 19.5 29.0 6.3 31.0 11.9 15.9 28.7 18.9 10.4 22.0 11.9 27.3 25.9 24.0 15.9 67.1 26.3 10.3 12.6 10.3 19.1 16.3 22.0 26.8 10.6 28.4 24.7 15.6 14.6 12.3 12.3 16.3 19.8 15.3 13.5 15.4 15.6 13.0 12.2 13.1 3.6 21.6 22.7 16.3 16.0 13.7 10.1 11.5 14.0 16.3 11.8 10.1 12.4 11.0 12.8 9.9 12.1 12.1 54.2 83.3 51.5 41.1 49.9 42.8 48.9 57.6 62.0 132.2 51.6 72.8 80.8 38.6 47.7 33.1 120.9 60.2 83.4 62.6 68.4 35.4 1.2 28.0 45.9 55.7 49.8 31.1 57.0 29.3 43.0 46.6 36.7 37.0 44.3 44.9 38.2 54.0 43.8 52.2 54.6 64.1 40.7 44.0 29.1 3.7 49.7 47.1 28.4 36.5 60.8 39.8 59.8 44.7 40.7 29.8 63.0 52.3 55.0 65.4 77.4 78.5 33.2 265.8 46.0 52.7 76.1 15.3 25.9 83.5 58.2 38.2 48.2 40.6 58.6 45.4 VWA2 "AMACO, CCSP-2, FLJ16213, FLJ45857, NET42" ENSG00000165816 "Von Willebrand factor A domain containing 2" Q5GFL6 10 114239254-114294489 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 8.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 6.8;Early spermatids: 9.6;Gastric mucus-secreting cells: 5.1;Late spermatids: 15.8;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 5.7;HaCaT: 3.0;SCLC-21H: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037847 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA037847: AB_10670961" "unprognostic (6.03e-2)" "unprognostic (8.29e-2)" "unprognostic (3.27e-2)" "unprognostic (7.33e-2)" "unprognostic (1.26e-2)" "unprognostic (6.82e-2)" "unprognostic (3.02e-2)" "unprognostic (9.33e-3)" "unprognostic (2.44e-1)" "unprognostic (3.70e-1)" "unprognostic (1.37e-3)" "unprognostic (3.14e-1)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (9.30e-2)" "unprognostic (1.22e-1)" 0.5 0.0 2.7 0.4 1.6 0.5 3.1 2.2 1.6 4.0 0.3 1.3 1.6 0.9 1.0 1.2 6.4 0.2 0.0 1.4 1.3 0.5 0.0 3.3 0.2 1.9 1.7 0.1 2.3 0.2 0.3 0.4 1.8 5.4 1.0 0.3 4.5 1.0 0.3 6.4 1.4 0.1 1.7 1.4 8.4 1.1 2.1 3.4 0.8 0.2 0.5 0.7 0.9 1.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.3 0.0 0.0 3.0 0.0 0.6 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 1.6 0.0 0.0 0.6 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.7 1.6 2.2 1.6 1.4 1.3 1.9 1.7 1.8 1.7 2.1 1.5 0.4 0.0 0.0 0.0 0.0 0.3 4.1 2.8 6.8 0.0 1.1 0.3 0.5 0.0 1.7 1.8 0.0 1.3 0.0 0.1 0.0 2.1 9.6 0.7 0.1 0.2 0.0 0.0 4.1 1.6 0.0 0.1 5.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.4 2.0 0.0 0.0 15.8 0.3 0.0 0.0 16.9 0.0 0.0 0.0 2.5 0.1 2.2 0.2 0.0 0.0 2.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.8 0.3 1.1 0.0 0.7 0.0 0.1 0.5 1.3 WFDC12 "C20orf122, dJ211D12.4, WAP2" ENSG00000168703 "WAP four-disulfide core domain 12" Q8WWY7 20 45123425-45124465 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 42.0" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 2.6;Collecting duct cells: 5.5" "Group enriched" "Detected in many" 7 "head and neck cancer: 18.9;melanoma: 14.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 86000 "Cluster 31: Skin - Epidermis development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "unprognostic (1.18e-2)" "unprognostic (5.42e-2)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (3.40e-3)" "unprognostic (1.72e-2)" "unprognostic (8.70e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (4.49e-2)" "unprognostic (3.91e-1)" "unprognostic (5.50e-3)" 0.1 0.1 1.2 0.1 0.7 1.0 2.5 0.2 1.1 0.8 0.4 0.2 0.5 0.2 1.8 6.7 0.1 0.2 0.0 1.0 0.2 0.3 0.2 1.1 0.2 0.3 0.2 0.2 0.0 0.1 0.0 0.1 0.6 1.8 0.2 0.7 2.1 2.9 0.6 42.0 0.2 0.2 0.0 0.2 0.1 1.7 0.7 1.2 0.3 0.0 1.5 0.1 9.8 0.5 0.2 0.1 0.0 0.1 0.9 0.1 0.3 0.1 0.4 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.6 0.4 0.0 0.0 0.3 0.3 0.3 0.0 0.3 0.0 0.0 0.3 0.2 0.4 0.3 0.1 0.2 0.3 0.3 0.1 0.1 0.3 0.4 0.4 0.1 0.0 0.5 0.1 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.1 0.3 0.3 0.3 0.3 0.3 0.2 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.2 1.1 1.0 0.2 0.3 0.2 0.6 0.0 0.7 0.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.5 5.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 WNT10A ENSG00000135925 "Wnt family member 10A" Q9GZT5 2 218880852-218899581 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant, Ectodermal dysplasia, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 7.0;skin 1: 8.9" "Cell type enhanced" "Detected in many" "B-cells: 12.2;Basal keratinocytes: 17.1;Basal respiratory cells: 15.5;Basal squamous epithelial cells: 30.1;Bipolar cells: 16.2;dendritic cells: 16.4;Plasma cells: 30.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 6.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 6.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 50.8;HaCaT: 140.1;HDLM-2: 58.7;RPTEC TERT1: 29.2;U-266/70: 69.0" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Region enhanced" "Detected in single" "basal ganglia: 2.1" HPA013898 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "HPA013898: AB_1858847" "unprognostic (2.99e-4)" "unprognostic (4.31e-2)" "unprognostic (8.55e-2)" "unprognostic (1.17e-3)" "unprognostic (2.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.23e-3)" "unprognostic (9.52e-2)" "unprognostic (6.64e-9)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (4.89e-3)" "unprognostic (1.82e-1)" 0.7 0.2 0.7 1.0 1.6 0.5 0.5 0.2 1.3 1.5 0.2 1.6 3.7 0.0 0.4 7.0 1.2 0.3 0.1 1.2 0.5 2.4 0.2 0.7 2.5 0.4 0.6 0.2 0.1 0.0 4.3 3.4 0.5 1.7 1.0 1.4 2.5 1.0 0.0 8.9 2.1 0.0 0.3 2.0 2.5 0.4 0.7 1.1 0.2 0.0 1.9 2.7 2.9 0.7 15.8 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 50.8 2.8 10.4 0.0 3.8 140.1 0.0 0.1 0.0 58.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 10.5 29.2 0.4 0.0 0.4 0.3 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 69.0 1.1 1.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 6.2 1.0 0.0 0.7 1.6 0.2 1.3 1.2 0.5 0.4 0.6 0.5 0.3 0.7 0.7 0.2 0.0 0.0 0.3 12.2 17.1 8.2 15.5 30.1 16.2 0.5 1.3 1.4 0.0 1.1 9.2 2.1 1.2 16.4 0.0 0.0 0.3 1.2 0.3 0.1 0.2 0.0 0.4 1.3 0.0 0.4 1.9 0.5 0.2 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.0 2.0 0.0 1.3 0.1 0.6 1.0 7.2 0.0 0.0 0.5 0.0 0.5 0.1 0.1 0.0 0.0 30.4 2.5 0.0 0.3 0.6 1.5 0.0 0.1 0.8 0.9 0.6 5.2 4.7 0.1 9.8 0.0 0.2 3.2 WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 40.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.1;Breast glandular cells: 19.9;Breast myoepithelial cells: 24.3;Endometrial stromal cells: 71.4;Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;SCLC-21H: 10.2;SK-BR-3: 8.6;T-47d: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" 0.8 9.0 2.4 0.4 1.5 0.3 2.2 0.2 2.9 8.9 0.5 2.3 3.2 4.5 8.9 12.1 8.3 2.6 0.1 2.0 2.9 1.1 1.4 1.2 0.1 1.6 1.8 16.8 3.0 0.1 5.6 1.6 1.2 5.5 1.6 0.2 4.1 2.6 3.1 40.8 3.1 1.9 1.1 0.3 4.3 0.6 3.9 1.1 3.4 0.6 1.5 3.1 6.3 1.1 1.3 0.1 2.5 0.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.3 8.5 0.0 0.6 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 1.1 0.2 0.3 0.0 0.0 0.0 1.6 10.2 0.0 0.1 8.6 0.6 0.6 3.4 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.5 0.2 2.9 2.0 2.9 1.6 1.8 1.2 1.1 3.9 1.1 0.9 3.2 8.6 0.3 0.7 16.7 4.3 42.1 6.8 0.0 19.9 24.3 0.6 0.0 15.2 0.0 0.0 0.7 0.1 0.9 0.0 2.7 0.1 4.1 71.4 0.6 29.4 0.0 0.2 0.6 0.1 3.1 0.5 1.6 0.0 0.2 0.7 0.5 0.1 0.0 1.9 16.0 4.1 0.0 0.2 0.9 0.0 0.4 5.4 6.5 0.1 0.0 0.0 0.0 0.3 0.9 0.1 3.8 0.6 5.7 0.3 0.0 12.0 0.0 0.0 0.4 2.2 0.0 0.3 2.5 10.4 0.3 0.6 0.0 0.6 4.2 XG PBDX ENSG00000124343 "Xg glycoprotein (Xg blood group)" P55808 X 2752040-2816500 "Blood group antigen proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.5;skin 1: 38.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.4;Basal respiratory cells: 15.1;Basal squamous epithelial cells: 30.7;Fibroblasts: 30.1;Melanocytes: 10.6;Squamous epithelial cells: 10.1;Suprabasal keratinocytes: 21.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 63.7;ASC TERT1: 50.6;fHDF/TERT166: 31.5;hTCEpi: 49.6;T-47d: 28.2" "Low region specificity" "Detected in all" NA NA 22000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "prognostic unfavorable (4.25e-4)" "unprognostic (1.69e-2)" "unprognostic (1.40e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (3.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" "unprognostic (8.62e-2)" "unprognostic (7.21e-2)" "unprognostic (2.30e-1)" "unprognostic (8.10e-6)" "unprognostic (3.96e-3)" "unprognostic (7.98e-2)" "unprognostic (5.83e-3)" "unprognostic (6.77e-3)" 17.5 0.0 0.0 0.1 0.0 1.2 8.9 0.1 0.0 12.0 0.0 0.3 0.1 1.2 0.0 11.7 0.8 3.3 2.6 0.1 0.1 0.3 0.7 0.6 0.3 0.3 0.2 0.2 0.1 0.1 0.1 1.8 0.2 0.8 0.1 0.0 7.6 0.6 3.2 38.6 0.1 0.2 0.3 0.1 0.3 0.1 0.0 2.2 1.9 5.0 3.1 2.1 12.7 0.7 0.1 0.0 0.0 0.1 63.7 50.6 0.6 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 31.5 0.0 5.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.1 49.6 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.2 4.2 0.1 28.2 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.2 0.2 0.3 0.0 0.7 3.3 0.0 0.0 1.0 0.0 14.4 0.5 15.1 30.7 0.0 0.2 0.4 0.4 0.0 1.3 1.8 0.0 0.8 0.5 0.0 0.0 0.0 0.0 2.4 0.5 0.8 0.0 1.3 0.9 0.0 0.1 30.1 0.0 1.2 0.0 6.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 9.0 0.0 0.0 0.1 10.6 1.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 2.5 2.5 0.2 0.5 10.1 21.9 0.5 0.5 0.5 0.0 0.2 XKRX "XKR2, XPLAC" ENSG00000182489 "XK related X-linked" Q6PP77 X 100913445-100929433 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skin 1: 9.7" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 4.3;Inhibitory neurons: 6.0;Microglial cells: 3.7;Oligodendrocytes: 5.5;Syncytiotrophoblasts: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "naive B-cell: 1.9;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.2" "Group enriched" "Detected in many" 18 "B-cells: 1.9;T-cells: 1.5" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.35e-1)" "unprognostic (2.38e-2)" "unprognostic (4.51e-3)" "unprognostic (1.87e-1)" "unprognostic (8.53e-2)" "unprognostic (2.67e-2)" "unprognostic (2.96e-2)" "unprognostic (5.18e-2)" "unprognostic (3.69e-2)" "unprognostic (7.37e-2)" "unprognostic (5.70e-2)" "unprognostic (1.58e-2)" "unprognostic (5.60e-6)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.18e-1)" 0.0 0.6 0.5 0.8 0.3 0.1 0.6 0.1 0.3 0.7 0.0 0.7 0.3 0.2 1.1 2.3 0.6 0.1 0.0 0.2 1.7 0.1 0.0 1.2 1.6 0.3 0.4 0.2 0.0 0.0 1.0 0.3 0.3 0.3 0.8 0.2 0.5 0.9 0.1 9.7 2.4 0.1 0.2 0.5 0.3 0.2 1.2 1.8 0.4 0.0 3.5 0.3 1.7 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 8.2 1.0 0.6 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.5 0.6 0.0 0.0 0.0 0.4 0.1 0.0 0.3 1.6 0.0 0.0 0.0 1.6 0.1 1.3 0.2 0.7 0.1 0.7 0.0 0.1 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.2 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.9 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.1 0.3 0.2 1.7 0.3 0.4 0.3 0.2 1.2 0.2 0.0 0.0 0.0 9.4 0.7 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 1.8 3.7 0.1 0.2 0.0 1.0 5.5 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.9 2.6 0.2 0.0 0.2 0.4 ZBTB7B "c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B" ENSG00000160685 "Zinc finger and BTB domain containing 7B" O15156 1 155002630-155018522 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.2;Proximal enterocytes: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006811, HPA025820" Enhanced Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA006811: AB_1859046, HPA025820: AB_1859045" "unprognostic (5.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-2)" "unprognostic (2.43e-1)" "unprognostic (4.95e-3)" "unprognostic (9.55e-2)" "unprognostic (1.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.46e-2)" "unprognostic (5.35e-2)" "unprognostic (1.11e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-2)" 24.9 35.3 12.9 18.1 15.8 30.0 27.9 15.8 12.9 25.3 11.7 55.4 61.9 16.1 6.4 95.4 17.9 11.0 25.2 11.2 13.6 19.7 48.4 25.0 16.2 18.3 17.5 12.7 29.9 15.6 20.0 9.0 17.3 30.5 18.6 6.5 40.2 12.8 40.6 111.9 71.2 9.9 15.8 31.6 37.7 6.1 17.7 9.0 25.5 17.6 15.2 20.4 44.4 17.9 16.5 29.0 2.5 8.8 12.7 7.2 34.7 11.1 13.1 11.4 13.2 19.5 23.4 7.2 19.5 12.6 9.1 24.5 8.1 15.7 2.4 39.4 9.1 12.0 51.4 13.1 18.6 9.2 31.7 9.4 54.8 15.6 19.3 15.3 9.1 1.1 17.3 32.2 6.7 31.2 0.2 20.7 8.7 26.4 23.8 6.8 1.9 45.6 17.2 16.9 16.1 16.5 21.4 56.5 8.9 10.6 35.2 30.7 7.7 7.4 12.9 14.8 9.5 38.1 25.1 7.6 17.3 30.3 8.6 0.4 1.5 1.3 0.6 1.4 0.2 0.6 0.7 0.3 0.9 0.7 0.6 0.2 2.3 0.7 1.2 0.0 1.0 2.5 12.9 15.8 15.8 12.9 11.2 13.6 18.3 17.5 17.3 15.8 17.7 17.9 6.5 9.6 0.0 11.1 8.5 35.2 9.3 8.8 29.6 13.6 35.2 15.6 2.6 18.6 7.1 5.5 2.1 11.9 6.9 135.2 11.7 13.3 4.3 15.4 6.7 5.6 6.7 6.1 1.0 15.1 14.6 4.9 27.5 21.3 5.7 2.8 6.1 29.9 14.8 16.8 1.1 32.7 14.2 28.7 40.3 8.3 9.0 20.7 16.0 4.7 25.8 5.4 11.3 0.0 8.6 16.8 57.7 7.2 6.8 24.9 158.5 10.0 4.2 10.3 0.0 3.2 5.7 0.5 1.2 51.7 53.6 27.5 11.3 4.4 38.5 24.4 ZC2HC1A "C8orf70, CGI-62, FAM164A" ENSG00000104427 "Zinc finger C2HC-type containing 1A" Q96GY0 8 78666089-78719765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 44.6" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 45.1;T-reg: 33.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 42.1;SK-BR-3: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024726 Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Actin filaments" "HPA024726: AB_1846597" "unprognostic (1.12e-1)" "unprognostic (3.02e-1)" "unprognostic (5.36e-3)" "unprognostic (4.00e-2)" "unprognostic (1.13e-1)" "unprognostic (7.79e-2)" "unprognostic (1.19e-7)" "unprognostic (2.96e-1)" "unprognostic (7.25e-2)" "prognostic unfavorable (9.00e-4)" "unprognostic (2.26e-1)" "unprognostic (1.63e-2)" "unprognostic (5.41e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.34e-1)" "unprognostic (5.40e-2)" "unprognostic (4.05e-3)" 6.5 5.5 8.4 5.7 9.5 1.6 13.8 11.0 9.9 10.7 1.7 6.2 2.7 19.5 8.4 11.1 19.0 9.7 8.2 9.4 8.4 7.7 2.3 12.6 5.3 9.3 6.9 22.7 3.7 24.0 8.5 6.6 10.1 12.2 7.3 10.9 7.3 9.9 2.4 44.6 4.2 12.1 6.3 5.8 5.5 8.8 7.6 5.1 19.7 6.3 8.4 9.0 8.8 10.9 5.2 6.3 11.6 9.5 24.1 25.2 5.0 14.1 9.4 6.9 8.8 1.7 9.0 8.6 5.8 14.2 14.5 4.2 7.0 7.8 10.1 28.6 4.5 1.0 5.5 5.2 14.3 1.5 2.8 18.2 13.0 5.6 16.8 21.1 9.6 2.9 1.6 42.1 14.6 5.1 1.7 2.5 2.9 0.4 9.9 0.0 14.8 1.8 10.4 11.0 4.5 18.0 11.0 79.2 15.8 10.7 2.0 0.3 7.9 21.4 8.9 9.9 7.1 10.5 11.4 5.8 10.1 0.1 8.3 45.1 6.7 0.2 0.1 7.5 0.0 8.8 6.7 0.4 6.0 6.3 2.0 0.7 0.3 1.2 15.9 0.5 33.3 2.7 8.4 9.5 11.0 9.9 9.4 8.4 9.3 6.9 10.1 6.3 7.6 10.9 21.7 67.3 23.7 71.8 17.0 29.2 38.7 39.9 52.3 26.3 12.3 47.5 15.9 5.7 27.4 18.4 4.2 29.0 1.0 1.8 27.4 18.1 16.3 55.5 38.0 17.5 9.0 1.7 96.4 8.2 29.9 34.5 13.3 25.8 6.3 18.8 21.8 0.8 15.9 47.1 68.3 4.2 16.2 6.0 11.3 5.9 19.3 11.1 16.0 14.0 18.5 39.2 0.0 65.9 52.4 9.4 2.4 36.9 12.5 13.1 0.1 11.8 105.5 25.5 6.6 32.0 33.9 48.6 32.2 26.0 42.3 17.4 6.5 9.4 4.4 14.6 ZFP64 "dJ548G19.1, dJ831D17.1, FLJ10734, FLJ12628, ZNF338" ENSG00000020256 "ZFP64 zinc finger protein" Q9NTW7 20 52051663-52204308 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035112, HPA058387" Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA035112: AB_10672859, HPA058387: AB_2683702" "unprognostic (3.86e-2)" "unprognostic (8.84e-2)" "unprognostic (2.34e-1)" "unprognostic (4.61e-3)" "unprognostic (9.22e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.86e-7)" "unprognostic (4.68e-2)" "unprognostic (5.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-3)" "unprognostic (2.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" 4.2 4.8 5.8 5.7 5.5 5.3 4.6 5.2 5.5 5.7 3.0 6.3 6.6 5.7 4.2 7.0 6.7 5.3 4.8 5.1 3.4 4.7 5.2 4.5 6.6 4.7 3.4 7.8 5.6 7.2 4.7 4.3 4.6 6.3 5.7 5.0 5.8 5.7 5.4 11.2 5.9 5.5 2.6 5.7 5.9 6.6 4.5 7.3 6.8 4.5 5.3 5.6 6.1 5.6 35.1 19.6 14.7 35.1 7.2 13.0 21.0 11.9 17.3 25.5 21.1 18.8 14.3 15.5 23.2 21.5 21.1 46.2 12.0 26.6 15.6 6.6 37.5 9.3 35.0 20.1 19.9 10.4 6.6 11.3 39.4 13.0 14.8 13.0 17.6 16.4 11.2 19.5 6.4 14.6 14.5 8.9 14.8 19.0 15.1 15.9 7.6 15.6 12.1 13.9 15.2 18.0 23.1 28.6 22.5 12.0 19.2 12.3 11.6 18.0 26.1 19.7 7.7 21.1 20.6 12.6 17.2 10.3 12.2 5.1 3.3 8.1 4.5 1.8 3.3 5.1 3.4 3.6 4.2 3.2 3.8 3.7 1.8 5.3 4.8 4.1 3.3 2.8 5.8 5.5 5.2 5.5 5.1 3.4 4.7 3.4 4.6 2.6 4.5 5.6 4.7 3.2 3.3 7.2 5.4 8.7 4.3 5.4 19.9 5.1 5.1 3.9 4.0 4.3 2.5 0.0 2.1 4.3 6.2 7.5 7.9 8.2 7.4 3.9 4.4 4.2 6.7 5.5 18.0 5.8 8.5 5.9 9.7 3.9 7.0 5.2 9.3 6.1 4.0 1.7 15.5 9.5 8.2 4.1 4.2 9.1 6.5 2.9 3.6 14.0 4.0 2.7 7.2 15.6 18.6 5.4 6.0 7.2 11.6 3.5 5.3 4.9 4.0 4.7 6.6 3.8 5.5 19.7 2.9 11.3 13.4 1.2 5.8 3.9 9.0 2.6 ZNF16 KOX9 ENSG00000170631 "Zinc finger protein 16" P17020 8 144930358-144950888 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035782, HPA061835" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Nucleoli Nucleoplasm "HPA035782: AB_10603243, HPA061835: AB_2684621" "unprognostic (4.11e-2)" "unprognostic (1.51e-2)" "unprognostic (6.87e-2)" "unprognostic (2.45e-1)" "unprognostic (2.69e-1)" "prognostic favorable (2.39e-4)" "unprognostic (7.53e-3)" "unprognostic (1.10e-1)" "unprognostic (1.24e-1)" "unprognostic (8.50e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.70e-2)" "unprognostic (2.96e-1)" "unprognostic (9.75e-2)" "unprognostic (4.17e-3)" 4.6 3.6 4.6 2.4 4.7 2.6 6.3 4.4 5.0 6.0 5.9 6.5 4.7 6.2 6.9 5.9 7.1 5.7 4.4 4.5 4.4 5.3 3.9 3.7 3.2 4.2 4.2 11.0 7.5 8.6 4.0 3.9 4.3 5.4 4.7 5.1 4.6 5.6 8.3 9.3 4.8 5.5 4.5 3.4 5.0 7.5 4.8 4.4 7.0 8.3 3.9 5.7 6.0 4.6 4.5 3.9 7.7 4.2 6.4 9.0 5.5 4.0 8.9 8.0 7.2 3.1 4.5 7.1 5.2 5.2 4.3 3.5 5.4 8.9 7.2 3.1 4.5 8.2 4.4 4.5 10.7 3.0 4.6 10.9 8.8 5.1 13.2 7.9 4.4 5.3 5.7 4.7 6.4 6.2 6.1 3.0 4.7 6.9 8.8 7.5 4.5 4.5 6.8 6.7 6.4 4.7 8.5 5.1 6.9 5.8 9.5 5.6 4.7 3.6 7.5 4.3 4.5 3.4 3.1 6.4 4.1 4.0 5.8 2.6 3.0 2.2 4.9 2.9 5.6 2.8 3.8 4.5 4.8 4.4 3.8 3.5 0.4 9.2 3.0 2.5 5.8 3.2 4.6 4.7 4.4 5.0 4.5 4.4 4.2 4.2 4.3 4.5 4.8 4.6 3.6 3.2 4.4 4.9 3.4 2.7 6.9 6.8 5.2 11.4 4.3 2.9 3.7 5.7 3.1 9.2 12.5 5.9 7.0 3.2 1.9 7.3 10.3 2.0 3.5 3.7 4.2 3.0 6.8 4.4 3.6 3.8 5.1 3.9 7.0 9.4 5.0 4.5 3.6 6.7 6.3 5.6 6.1 3.5 2.4 3.7 6.2 2.1 1.8 6.5 5.4 6.2 7.2 6.6 7.2 3.6 4.9 6.4 3.2 4.2 10.6 4.8 3.4 25.1 0.0 3.4 4.0 13.6 18.1 4.5 4.5 5.5 5.1 6.6 5.4 5.5 ZNF440 FLJ37933 ENSG00000171295 "Zinc finger protein 440" Q8IYI8 19 11814273-11835216 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 44.8;Respiratory ciliated cells: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 12.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 12.6" "Cell line enhanced" "Detected in many" "RT4: 25.5" HPA047845 Approved Approved Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA047845: AB_2680178" "unprognostic (2.48e-1)" "unprognostic (8.96e-3)" "unprognostic (1.34e-1)" "unprognostic (4.40e-2)" "unprognostic (2.45e-3)" "unprognostic (1.24e-3)" "unprognostic (1.03e-1)" "unprognostic (3.13e-2)" "unprognostic (9.05e-2)" "unprognostic (4.64e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (3.57e-4)" "prognostic favorable (1.18e-4)" "unprognostic (9.81e-3)" "unprognostic (2.22e-1)" "unprognostic (3.80e-2)" "prognostic favorable (9.88e-4)" 3.8 3.9 2.8 3.4 2.5 6.9 6.8 6.3 3.6 6.1 7.4 10.0 5.6 4.4 4.8 9.8 14.5 4.3 3.3 5.0 1.8 4.7 3.7 6.9 4.2 3.7 5.3 3.8 5.5 16.4 2.8 9.7 3.1 6.3 11.1 7.1 7.1 4.3 4.3 15.6 7.1 3.5 1.2 4.3 8.6 6.4 2.4 8.0 4.1 2.2 5.2 11.6 7.1 4.8 6.7 0.0 7.3 8.9 5.4 4.8 19.4 4.6 3.8 5.5 4.7 7.0 5.7 3.7 4.4 4.2 2.7 8.2 3.8 8.9 7.6 0.3 2.5 5.2 4.8 5.6 2.7 0.1 11.5 2.7 5.8 3.4 0.9 3.9 3.1 5.0 19.9 0.3 6.4 2.8 4.7 6.9 5.6 2.3 5.8 3.9 9.5 1.6 4.0 25.5 4.2 3.3 7.2 3.0 5.3 7.8 12.9 10.3 3.3 12.5 2.6 9.2 4.1 6.7 5.2 4.9 5.8 3.3 4.6 12.6 1.4 1.9 1.1 0.9 1.4 1.0 1.4 1.3 1.8 1.1 1.0 1.6 2.5 3.0 2.9 1.1 1.8 0.8 2.8 2.5 6.3 3.6 5.0 1.8 3.7 5.3 3.1 1.2 2.4 4.8 3.9 16.0 7.9 7.2 2.5 2.9 7.6 5.2 8.0 5.5 3.4 2.7 3.0 1.5 14.6 9.2 35.5 31.1 5.8 25.1 3.9 3.6 16.7 44.8 3.8 4.2 6.7 2.1 10.4 3.6 20.7 3.1 15.3 11.9 10.8 3.3 4.2 1.7 4.5 6.7 6.7 12.7 2.0 5.0 2.8 5.7 2.8 3.0 3.6 2.8 2.2 2.0 4.1 10.6 5.8 5.8 15.9 1.9 2.5 5.7 20.8 2.1 74.1 13.1 0.0 3.9 4.1 9.7 3.5 9.0 4.8 29.8 4.6 1.1 12.1 9.8 ZNF786 DKFZp762I137 ENSG00000197362 "Zinc finger protein 786" Q8N393 7 149069641-149090782 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.8;Horizontal cells: 18.5;Inhibitory neurons: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021518, HPA053459" Uncertain Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Nucleoplasm, Nuclear bodies" "HPA021518: AB_2670734, HPA053459: AB_2682159" "unprognostic (3.13e-2)" "unprognostic (2.72e-1)" "unprognostic (5.61e-2)" "unprognostic (5.39e-2)" "unprognostic (1.87e-1)" "unprognostic (2.84e-2)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.62e-2)" "unprognostic (1.09e-3)" "unprognostic (8.85e-2)" "prognostic favorable (2.01e-4)" "unprognostic (3.97e-2)" "unprognostic (1.39e-2)" "unprognostic (8.86e-3)" "unprognostic (1.31e-1)" "unprognostic (3.44e-1)" "unprognostic (1.47e-2)" 2.0 2.2 2.9 2.8 2.6 1.5 2.6 3.9 4.3 3.5 1.1 3.1 2.0 3.3 2.4 3.8 3.1 2.0 2.0 2.8 2.6 2.9 3.1 1.9 3.8 1.6 1.7 3.2 2.6 2.3 3.8 1.6 1.5 3.7 1.4 1.9 3.0 2.2 2.0 5.6 3.1 1.9 0.9 3.9 2.3 1.6 2.8 3.5 2.9 2.3 2.8 3.3 3.5 2.8 4.5 8.1 6.1 10.4 3.7 1.5 8.7 2.7 2.8 2.9 2.3 4.3 4.0 6.3 6.3 1.9 5.1 5.0 3.8 3.6 1.9 6.9 5.9 3.2 5.1 5.4 3.1 6.3 4.1 2.2 4.0 3.6 2.6 3.0 2.7 4.5 5.6 3.5 2.7 13.9 10.7 10.5 11.4 4.1 6.0 7.7 3.0 4.1 2.4 6.1 7.3 11.5 6.6 6.1 5.0 3.8 3.9 3.0 3.6 3.4 2.0 6.0 3.9 12.7 10.0 3.5 5.7 3.9 3.8 1.8 3.4 2.9 10.4 4.7 8.8 6.4 7.5 9.4 4.3 5.9 9.7 8.3 1.1 8.5 4.0 3.7 5.0 5.0 2.9 2.6 3.9 4.3 2.8 2.6 1.6 1.7 1.5 0.9 2.8 2.8 2.4 0.0 1.1 3.6 3.5 2.7 2.6 4.2 2.8 10.1 2.3 1.3 2.7 1.5 1.6 3.7 2.1 2.4 5.9 2.0 3.9 4.1 0.4 0.9 2.1 3.1 4.8 0.8 18.8 1.5 2.5 2.6 6.6 1.1 4.5 4.5 1.8 2.4 2.2 18.5 15.8 1.6 2.0 1.9 2.6 0.4 3.1 2.1 0.0 3.7 3.6 2.8 13.4 7.1 5.4 1.8 3.3 4.1 2.9 1.4 1.7 2.5 2.3 6.0 0.0 3.3 2.5 4.9 8.3 2.3 1.7 1.9 6.0 1.8 2.7 1.7