Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AASDHPPT "AASD-PPT, ACPS, CGI-80, LYS5" ENSG00000149313 "Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase" Q9NRN7 11 106075501-106098699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 388.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026687 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA026687: AB_1844414" "unprognostic (1.96e-2)" "unprognostic (4.40e-1)" "unprognostic (8.71e-3)" "unprognostic (2.12e-1)" "unprognostic (1.11e-1)" "unprognostic (9.04e-3)" "unprognostic (2.82e-3)" "unprognostic (1.41e-1)" "unprognostic (2.44e-2)" "unprognostic (7.92e-2)" "unprognostic (2.09e-1)" "unprognostic (1.32e-1)" "prognostic favorable (4.27e-4)" "unprognostic (2.13e-1)" "unprognostic (2.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.43e-1)" 16.9 23.5 28.7 18.4 30.7 15.8 21.2 28.1 47.9 17.6 20.9 13.6 13.6 20.3 25.8 21.1 20.6 13.4 27.7 32.1 32.5 34.1 33.6 15.4 22.6 27.5 26.6 20.9 33.3 20.1 11.4 27.9 27.5 18.9 14.0 32.3 24.5 17.1 32.8 17.1 11.9 18.3 29.9 17.3 13.5 37.5 28.2 21.3 22.1 32.4 23.9 18.4 11.6 32.6 29.6 28.2 84.7 63.5 41.4 54.6 34.3 43.1 36.7 58.7 45.0 61.2 53.3 91.4 98.2 28.2 57.2 37.8 77.0 57.6 59.0 55.8 39.3 84.6 19.5 45.0 64.3 73.5 35.2 53.8 72.8 47.0 63.8 40.5 49.6 39.8 95.2 22.2 57.6 16.7 79.8 63.6 36.9 40.2 39.4 55.7 81.3 103.7 70.4 32.5 63.0 58.3 47.5 45.8 43.6 49.1 60.2 50.0 41.9 49.7 47.6 35.3 45.6 30.7 53.7 90.0 22.4 100.0 57.9 63.2 21.6 23.9 20.6 27.9 29.2 26.7 23.9 22.7 21.8 20.8 27.4 26.4 6.9 31.9 28.1 19.2 30.6 18.2 28.7 30.7 28.1 47.9 32.1 32.5 27.5 26.6 27.5 29.9 28.2 32.6 32.4 32.1 31.7 18.3 33.8 20.0 28.2 39.4 56.3 35.0 23.4 31.9 24.1 34.3 29.8 18.4 2.1 78.4 27.7 7.3 39.2 33.5 388.5 31.6 42.2 23.9 18.6 47.9 36.0 24.3 63.8 33.9 23.4 29.4 29.8 41.9 17.2 36.5 39.0 21.9 34.8 12.6 30.5 24.9 13.0 70.2 32.3 27.9 32.0 15.0 29.9 67.4 19.6 32.6 43.4 22.6 10.2 26.7 45.1 23.5 11.1 81.4 47.6 20.0 13.1 30.8 38.2 47.8 37.5 46.2 24.4 39.4 33.1 62.9 13.5 19.6 ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 197.6;Cardiomyocytes: 61.7;Hepatocytes: 116.0;Oligodendrocyte precursor cells: 63.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 75.3;HHSteC: 77.6;HSkMC: 89.4;hTERT-HME1: 90.9;hTERT-RPE1: 76.2;TIME: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" 68.4 7.4 19.2 3.8 18.0 0.5 57.6 49.7 19.1 12.5 6.8 11.1 2.7 10.4 6.3 33.2 14.4 7.1 87.8 20.4 26.7 19.8 115.8 20.0 5.3 37.2 25.2 3.9 2.7 59.6 6.8 34.4 28.7 9.1 5.0 28.6 6.5 8.2 45.8 8.3 7.8 10.6 34.0 8.7 5.4 2.0 29.9 2.2 9.2 38.7 4.5 14.1 17.7 30.2 23.6 4.8 0.0 0.2 39.6 75.3 0.1 16.1 44.8 9.1 15.8 0.1 16.2 0.0 2.7 20.5 47.9 0.5 0.1 18.9 17.7 0.1 0.2 0.0 1.4 0.6 77.6 0.0 0.1 89.4 5.1 32.5 90.9 76.2 41.1 0.0 0.0 7.2 54.8 9.2 0.0 0.0 0.2 1.5 63.0 0.0 0.1 0.0 50.3 16.0 6.3 0.1 3.3 1.1 8.7 1.2 1.5 0.1 103.9 18.9 4.2 19.9 27.7 0.1 0.0 0.0 33.5 0.0 55.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 2.7 19.2 18.0 49.7 19.1 20.4 26.7 37.2 25.2 28.7 34.0 29.9 30.2 197.6 0.0 3.7 21.5 1.3 1.5 1.2 2.6 0.6 2.5 7.6 3.9 61.7 18.6 5.3 0.0 0.0 0.2 0.3 0.0 5.9 8.7 3.0 0.5 2.5 39.6 0.0 0.0 31.0 3.5 0.7 9.4 3.6 2.5 1.3 0.0 34.2 116.0 12.3 28.6 33.7 0.0 8.2 13.5 1.1 0.5 0.3 8.5 5.4 21.5 0.9 19.3 0.0 63.8 25.6 22.5 0.0 0.7 0.1 2.5 0.0 23.5 4.9 25.1 0.0 7.4 7.7 1.7 2.7 2.0 1.6 0.4 0.7 0.5 0.0 22.2 AC093668.1 ENSG00000270249 "Novel protein" 7 102541501-102592444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.1;hTERT-RPE1: 1.0;Karpas-707: 1.0" HPA046970 Uncertain Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA046970: AB_2679882" 0.3 0.4 0.2 0.4 0.4 0.4 0.3 1.1 1.4 0.6 0.3 0.6 1.0 0.5 1.0 0.2 0.5 0.0 0.3 0.6 0.4 0.5 0.0 0.4 0.3 0.4 0.4 0.4 0.5 2.1 1.2 0.2 0.7 0.3 0.3 1.8 0.4 0.1 2.1 0.9 0.6 0.0 0.1 0.7 0.6 0.1 0.4 0.3 0.2 0.4 0.1 0.3 0.4 1.2 0.0 0.0 0.3 0.0 0.0 1.1 0.1 0.2 0.2 0.2 0.0 0.0 0.7 0.7 0.1 0.5 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 1.0 0.0 0.1 0.9 0.4 0.1 0.8 0.3 0.4 0.0 0.1 0.1 0.3 0.5 0.3 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.5 0.1 0.1 0.3 0.0 0.0 0.3 0.2 1.4 0.4 1.8 2.0 1.8 1.4 0.8 1.3 2.4 1.4 0.6 0.3 0.4 1.6 2.8 0.6 0.2 0.4 1.1 1.4 0.6 0.4 0.4 0.4 0.7 0.1 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC104109.3 ENSG00000272772 "Novel protein" 5 134167170-134226071 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "brain: 1.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;granulocytes: 1.3;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.22e-2)" "unprognostic (2.97e-2)" "unprognostic (1.84e-2)" "unprognostic (6.66e-2)" "unprognostic (9.48e-2)" "unprognostic (1.38e-2)" "unprognostic (9.97e-3)" "unprognostic (1.70e-1)" "unprognostic (9.90e-2)" "unprognostic (2.20e-1)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (4.81e-2)" 0.1 0.2 0.1 0.4 0.0 0.2 0.1 0.0 1.2 0.1 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.0 0.9 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.3 0.1 0.0 0.4 0.3 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.8 0.2 0.5 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.4 0.8 0.0 0.5 2.9 0.3 0.0 1.6 3.3 0.9 0.9 1.0 0.0 1.4 1.5 0.7 0.0 2.9 1.4 1.5 0.0 0.8 1.4 1.1 3.3 1.5 0.6 0.0 0.9 1.0 0.0 0.0 1.2 0.8 0.7 0.2 0.5 0.9 0.2 1.0 0.6 1.3 0.4 1.4 0.5 0.0 2.4 1.5 0.2 0.0 0.4 2.8 0.7 3.2 0.4 1.0 0.7 1.6 0.6 2.6 1.7 0.3 2.0 2.8 1.0 4.4 2.0 1.1 1.3 1.4 0.0 0.6 0.0 0.3 0.0 0.9 0.5 0.3 0.1 0.3 0.2 0.0 0.8 0.8 1.2 0.1 0.1 0.3 0.3 0.1 0.0 0.0 1.2 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.4 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 ACAD8 ENSG00000151498 "Acyl-CoA dehydrogenase family member 8" Q9UKU7 11 134253548-134265855 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism, Transcription, Transcription regulation" "Activator, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040689, HPA043903" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA040689: AB_2677080, HPA043903: AB_2678724" "unprognostic (5.00e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.62e-4)" "unprognostic (7.57e-3)" "unprognostic (9.83e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.53e-1)" "prognostic favorable (2.38e-4)" "unprognostic (4.10e-2)" "unprognostic (2.84e-1)" "unprognostic (7.81e-3)" "unprognostic (2.16e-1)" "prognostic favorable (6.42e-10)" "unprognostic (1.08e-1)" "unprognostic (1.17e-2)" "unprognostic (4.02e-2)" "unprognostic (1.03e-2)" 11.0 18.1 13.9 3.5 14.2 6.8 11.3 14.3 15.4 7.5 18.7 11.6 11.3 6.3 12.6 9.6 9.4 5.2 27.2 14.7 14.3 31.6 24.8 7.8 5.0 14.3 14.1 6.9 16.7 12.4 6.5 4.8 13.8 20.5 10.9 5.0 12.6 7.5 32.5 14.3 8.4 8.3 14.5 8.6 12.6 6.3 14.8 8.5 27.7 39.2 8.9 8.4 6.9 14.8 5.9 5.9 11.8 17.6 20.2 11.5 13.5 11.3 14.0 14.7 10.3 16.2 10.8 14.2 21.1 11.7 15.5 6.0 14.6 14.3 10.2 13.0 4.7 29.4 5.8 11.3 17.0 16.5 18.3 13.8 4.4 14.8 4.5 13.3 16.3 20.8 13.8 7.0 12.4 7.5 12.2 18.1 17.0 49.8 9.7 9.8 11.9 8.5 20.1 17.5 3.7 11.7 19.5 14.8 7.3 11.9 31.0 15.0 11.3 7.1 7.5 6.2 11.2 7.8 3.8 12.7 7.2 15.4 11.2 36.2 13.4 23.1 11.8 13.5 11.5 11.6 11.1 11.7 12.7 9.2 13.0 11.7 12.1 31.5 12.9 10.8 15.1 12.3 13.9 14.2 14.3 15.4 14.7 14.3 14.3 14.1 13.8 14.5 14.8 14.8 11.7 3.2 12.2 15.3 8.8 6.0 4.7 23.5 7.4 11.2 17.5 11.9 24.6 4.3 19.7 18.4 14.6 19.7 14.0 20.0 52.8 12.1 5.3 8.2 11.8 9.7 3.6 12.0 21.5 11.9 10.6 9.8 10.2 8.5 3.8 15.7 10.8 36.7 12.9 15.2 16.0 14.3 48.8 14.2 6.9 6.1 11.5 10.0 28.4 13.1 12.7 11.8 9.2 12.1 15.8 12.6 15.8 10.1 14.6 5.9 17.4 59.8 20.1 17.1 6.6 8.7 9.6 22.4 17.3 10.9 7.7 8.3 10.5 36.0 14.9 5.3 ACBD5 "DKFZp434A2417, KIAA1996" ENSG00000107897 "Acyl-CoA binding domain containing 5" Q5T8D3 10 27168135-27243046 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Transport" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011861, HPA012145" Enhanced Enhanced Peroxisomes NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" Peroxisomes "HPA011861: AB_1844493, HPA012145: AB_1844494" "prognostic unfavorable (3.33e-4)" "unprognostic (4.93e-1)" "unprognostic (3.68e-1)" "unprognostic (1.34e-1)" "unprognostic (6.21e-2)" "unprognostic (5.98e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (2.69e-1)" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-2)" "prognostic favorable (4.68e-5)" "unprognostic (7.91e-3)" "unprognostic (1.71e-1)" "unprognostic (3.63e-2)" "unprognostic (3.37e-3)" 14.6 25.1 31.0 13.5 37.0 18.2 12.3 36.2 37.1 13.2 24.2 20.3 39.8 9.4 9.7 12.0 12.0 15.4 40.4 27.6 33.1 37.3 73.8 14.7 14.7 37.2 34.0 9.9 11.1 31.2 6.4 13.4 38.1 15.2 20.9 36.2 10.3 11.4 31.0 17.3 39.2 8.8 36.7 14.7 21.0 19.3 36.1 12.2 27.8 36.6 12.7 13.5 7.5 38.8 25.8 76.5 17.1 18.0 19.1 17.3 20.1 32.3 12.1 28.1 33.5 19.4 39.9 10.7 27.0 22.4 23.4 21.1 23.2 16.3 23.0 26.2 23.9 16.5 23.1 15.2 20.6 11.0 20.9 16.7 17.7 23.5 12.8 24.9 20.5 16.7 13.6 19.5 35.7 20.0 21.1 9.4 13.1 35.2 10.0 17.4 42.5 20.2 44.1 22.4 21.3 45.5 35.4 38.3 17.9 18.9 18.8 11.5 30.4 27.2 15.2 43.7 25.9 19.4 28.1 20.7 27.4 24.6 12.0 12.5 13.0 10.2 15.3 12.7 15.2 6.4 7.5 12.4 13.0 7.0 5.0 11.0 11.1 10.3 15.1 8.5 7.4 8.0 31.0 37.0 36.2 37.1 27.6 33.1 37.2 34.0 38.1 36.7 36.1 38.8 23.3 25.6 29.9 17.9 16.0 9.7 4.1 14.5 7.4 30.8 14.5 10.8 83.0 15.7 25.2 31.3 25.0 9.6 27.4 22.4 33.2 22.1 43.1 33.7 20.2 18.7 10.2 8.6 20.6 16.2 12.6 16.4 19.4 41.1 12.6 11.5 12.8 56.9 19.0 23.5 26.9 30.4 10.2 25.5 12.5 16.9 16.4 22.4 21.4 15.9 22.4 47.7 29.9 17.6 24.8 17.8 26.1 16.6 14.2 11.7 64.4 48.2 32.7 47.2 19.7 20.9 16.1 41.0 8.3 16.5 15.5 10.4 22.3 27.1 26.5 9.2 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 374.2;Proximal tubular cells: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 88.8 81.6 154.2 38.6 152.2 32.0 52.4 153.0 190.0 39.5 160.1 94.4 162.9 42.0 26.1 60.4 53.6 36.5 567.7 155.2 153.1 138.9 73.9 40.7 40.5 146.1 145.3 30.8 53.8 233.8 33.6 30.5 147.8 41.2 69.6 46.9 72.0 49.5 660.4 45.5 158.5 43.7 152.5 44.7 110.2 35.1 186.3 38.0 53.7 695.8 43.3 52.5 42.4 159.6 47.2 55.8 56.5 116.3 101.2 69.8 78.7 43.7 60.9 79.0 71.9 81.2 63.5 115.7 72.2 70.6 60.3 109.8 108.8 88.3 42.8 75.8 80.2 51.0 73.7 95.0 86.7 147.8 77.8 120.8 64.4 78.9 83.2 61.7 81.2 61.5 72.9 118.4 65.4 91.7 73.7 47.9 37.0 282.6 115.1 102.3 37.8 162.1 106.8 97.3 37.8 33.9 112.2 128.7 82.0 44.9 74.9 74.7 55.5 60.0 68.7 50.2 45.0 64.7 92.1 80.6 102.0 64.0 66.5 10.3 52.9 18.1 32.0 76.4 29.3 49.4 25.5 34.9 69.0 46.4 29.2 30.8 9.0 39.4 97.1 24.0 41.2 58.6 154.2 152.2 153.0 190.0 155.2 153.1 146.1 145.3 147.8 152.5 186.3 159.6 26.3 25.6 31.8 45.4 49.4 18.7 54.5 102.7 31.3 60.6 28.0 23.2 9.1 64.3 63.5 60.7 81.3 100.3 33.3 190.8 131.0 58.3 14.5 37.2 17.7 26.1 53.2 30.3 28.8 42.6 60.0 24.0 77.5 37.1 40.6 56.7 20.7 64.6 91.5 53.8 34.0 99.1 89.5 35.5 26.4 8.9 24.2 39.2 35.6 7.5 68.3 73.9 34.0 12.1 20.9 43.9 103.5 27.8 63.2 34.4 374.2 285.7 59.2 73.5 59.2 28.6 38.4 26.4 38.2 35.8 16.1 193.2 30.7 54.4 113.6 64.9 ACOT13 "HT012, THEM2" ENSG00000112304 "Acyl-CoA thioesterase 13" Q9NPJ3 6 24667035-24705065 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.6" "Cell type enhanced" "Detected in all" "Early spermatids: 847.1;Proximal tubular cells: 525.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019881, HPA057134" Enhanced Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" "Cell Junctions" "HPA019881: AB_1857978, HPA057134: " "unprognostic (3.61e-1)" "unprognostic (1.62e-1)" "unprognostic (6.02e-2)" "unprognostic (1.80e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "prognostic favorable (2.53e-6)" "unprognostic (3.67e-2)" "unprognostic (1.64e-2)" "unprognostic (7.16e-2)" "unprognostic (5.97e-2)" "unprognostic (4.86e-2)" "unprognostic (1.50e-1)" "unprognostic (2.13e-2)" 6.3 6.1 7.2 4.8 7.5 3.4 3.8 7.9 7.3 3.4 6.0 9.1 6.5 3.1 3.7 3.4 3.6 4.9 12.0 6.6 7.8 19.2 30.6 4.6 5.2 7.2 7.8 3.9 6.6 7.2 5.1 3.0 7.4 6.5 7.4 9.6 5.0 3.3 12.2 5.5 6.1 3.1 7.1 4.8 5.5 7.0 8.2 5.1 5.7 10.3 3.4 3.5 3.1 7.4 5.9 7.6 7.6 13.6 10.5 13.1 4.2 4.8 5.8 3.5 5.4 10.1 7.5 11.1 16.2 5.5 18.4 6.4 6.7 9.7 5.4 17.4 6.2 10.4 7.7 7.0 5.3 6.7 4.6 7.6 9.4 4.7 9.0 8.5 8.3 11.3 17.0 5.7 7.0 6.1 12.1 12.9 5.1 11.7 5.9 10.4 6.6 14.0 11.7 5.4 15.0 5.2 5.7 19.1 14.1 8.8 13.2 5.5 9.7 6.2 3.5 1.7 4.6 10.7 29.3 11.1 6.5 23.8 19.1 4.8 5.3 3.6 4.4 5.7 6.1 6.9 4.9 5.0 4.7 4.9 5.7 5.1 6.2 4.6 5.8 3.7 5.3 4.8 7.2 7.5 7.9 7.3 6.6 7.8 7.2 7.8 7.4 7.1 8.2 7.4 27.9 67.3 41.7 19.6 19.7 17.2 26.6 66.4 18.8 18.7 29.4 32.3 94.6 45.8 46.9 31.3 16.7 56.8 22.6 88.4 158.5 43.2 847.1 34.0 31.3 24.0 54.7 37.2 12.1 40.2 31.1 26.2 23.9 31.8 14.5 30.3 21.4 215.5 86.7 5.0 14.3 85.8 67.1 24.5 23.7 131.5 19.6 35.0 26.6 14.0 68.9 41.7 18.6 15.6 18.7 29.2 130.7 24.0 25.4 23.2 47.1 525.2 56.8 31.8 26.3 50.6 64.2 117.1 27.3 19.5 23.4 40.0 20.5 43.4 69.4 28.6 ACOT6 C14orf42 ENSG00000205669 "Acyl-CoA thioesterase 6" Q3I5F7 14 73610945-73619888 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;kidney: 3.7;liver: 3.1;skeletal muscle: 4.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.3;Excitatory neurons: 2.7;Hepatocytes: 3.4;Inhibitory neurons: 2.8;Proximal tubular cells: 5.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "T-47d: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058258 Uncertain NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA058258: AB_2683656" "unprognostic (1.88e-1)" "unprognostic (1.77e-1)" "unprognostic (5.17e-2)" "unprognostic (1.24e-1)" "unprognostic (3.15e-2)" "unprognostic (6.52e-2)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (2.28e-1)" "unprognostic (5.04e-1)" 1.7 0.6 0.8 0.1 1.3 0.0 0.1 5.0 2.5 0.0 2.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.8 1.2 0.0 3.7 3.1 0.1 0.1 0.6 0.3 0.5 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.2 0.0 4.0 0.0 0.1 0.0 0.4 0.2 0.0 0.5 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 1.8 0.1 0.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 5.0 2.5 1.2 0.0 0.6 0.3 1.0 0.4 0.5 0.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACTR1B "Arp1B, CTRN2" ENSG00000115073 "Actin related protein 1B" P42025 2 97655939-97664044 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047443 Approved Microtubules NA NA 49000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Microtubules "HPA047443: AB_2680049" "unprognostic (5.26e-2)" "unprognostic (8.91e-3)" "unprognostic (2.83e-3)" "unprognostic (2.67e-1)" "unprognostic (2.96e-1)" "unprognostic (2.82e-1)" "unprognostic (3.68e-3)" "unprognostic (1.37e-2)" "unprognostic (1.60e-2)" "unprognostic (7.84e-2)" "unprognostic (8.21e-2)" "unprognostic (6.29e-2)" "unprognostic (3.42e-2)" "unprognostic (2.78e-1)" "unprognostic (2.89e-2)" "unprognostic (4.58e-2)" "prognostic favorable (4.69e-4)" 38.5 68.3 60.0 24.9 61.0 38.8 41.9 54.1 66.4 41.1 59.3 52.1 36.1 48.1 21.5 37.5 43.4 26.0 68.6 60.6 57.0 47.0 54.3 36.7 30.9 57.3 55.2 47.1 72.9 51.1 41.4 20.6 58.4 43.6 22.1 22.0 45.4 37.3 86.9 39.3 43.2 26.5 56.6 57.8 52.1 20.8 58.2 33.2 45.8 68.8 24.8 44.0 36.4 57.7 52.8 28.5 27.1 35.8 49.1 39.8 78.1 49.2 74.2 34.6 28.9 22.5 28.1 38.0 45.3 50.5 37.1 28.4 21.9 56.5 14.6 76.6 36.8 28.2 28.3 62.1 38.3 22.8 43.1 39.7 41.5 22.0 67.7 51.8 39.0 46.8 20.1 44.8 52.1 58.5 44.2 28.6 27.5 40.1 38.1 24.7 39.6 63.2 55.0 41.1 31.7 23.8 23.7 48.1 36.2 34.8 38.1 35.9 41.1 23.0 35.6 24.7 20.8 57.7 27.0 13.7 68.8 32.5 21.1 11.7 15.0 19.2 19.1 13.5 14.6 14.6 20.9 19.2 21.1 14.7 17.2 18.8 5.7 14.9 20.5 8.5 29.7 16.4 60.0 61.0 54.1 66.4 60.6 57.0 57.3 55.2 58.4 56.6 58.2 57.7 43.8 19.2 18.2 15.0 30.4 13.6 30.9 28.4 16.5 38.5 24.9 20.8 32.8 22.8 22.2 22.0 12.5 29.0 26.1 26.5 35.2 69.2 13.2 16.2 16.4 30.9 25.8 24.6 33.4 58.0 57.7 24.3 23.4 13.1 29.9 20.4 28.2 18.7 29.1 55.5 26.4 31.7 36.7 18.5 20.0 10.0 24.2 17.4 23.2 12.2 57.3 29.5 43.3 17.1 26.1 42.8 32.8 26.7 21.9 55.5 59.9 40.5 22.2 30.0 39.5 25.3 28.5 13.1 31.7 29.9 16.3 16.3 31.4 47.7 36.4 39.8 ADAL ENSG00000168803 "Adenosine deaminase like" Q6DHV7 15 43330672-43354569 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 81.3;Rod photoreceptor cells: 84.8;Spermatocytes: 99.5;Spermatogonia: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039879, HPA048175, HPA058795" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear speckles, Vesicles" "HPA039879: , HPA048175: AB_2680298, HPA058795: " "unprognostic (1.65e-2)" "unprognostic (1.53e-3)" "unprognostic (9.80e-2)" "unprognostic (3.15e-3)" "unprognostic (2.46e-3)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "unprognostic (5.83e-2)" "unprognostic (5.90e-2)" "unprognostic (2.68e-1)" "unprognostic (6.85e-3)" "unprognostic (1.69e-1)" "prognostic favorable (7.64e-9)" "unprognostic (2.37e-3)" "unprognostic (8.77e-2)" "unprognostic (5.31e-2)" "unprognostic (2.44e-2)" 6.2 6.6 6.7 4.2 7.1 4.4 5.9 7.6 9.6 3.6 10.2 5.7 5.8 4.3 8.4 4.1 3.3 3.8 20.9 6.3 7.4 11.9 8.2 3.5 4.8 6.7 7.2 3.6 3.6 10.4 6.1 2.7 7.0 6.2 4.8 21.2 4.2 6.4 20.4 2.6 4.6 4.7 6.9 3.8 4.0 11.1 7.1 5.4 10.9 23.4 4.8 4.6 3.0 7.4 6.8 3.4 13.3 15.1 5.5 7.1 6.3 8.1 8.2 12.6 19.3 14.2 3.5 8.0 13.0 8.9 16.7 7.5 0.0 5.7 10.8 8.5 8.0 19.0 23.1 12.0 6.9 0.0 14.8 9.1 10.3 8.5 8.7 8.1 2.7 19.4 21.1 16.2 13.2 4.6 12.3 9.7 5.5 7.8 4.6 15.9 19.9 12.7 11.0 4.1 16.3 11.6 13.1 11.7 12.4 7.2 12.5 12.5 3.7 21.9 10.6 16.6 16.5 16.6 29.9 3.4 12.2 21.2 18.1 5.9 1.4 3.8 2.4 2.0 1.8 2.0 2.2 1.9 2.0 1.6 2.3 2.9 1.1 2.3 1.9 2.9 4.5 1.3 6.7 7.1 7.6 9.6 6.3 7.4 6.7 7.2 7.0 6.9 7.1 7.4 5.9 9.6 10.3 32.7 10.0 7.0 7.4 9.3 7.4 40.7 9.2 9.9 51.2 10.0 6.9 18.4 81.3 7.1 13.3 7.0 58.7 8.9 17.6 10.6 10.3 8.2 7.7 19.1 24.4 8.5 7.0 10.4 5.1 6.8 7.6 15.7 11.0 30.8 8.9 42.1 26.7 7.2 10.2 8.8 7.0 12.7 9.6 8.9 8.8 10.3 5.4 35.5 24.7 19.1 18.3 5.7 1.3 8.6 6.9 7.1 13.0 29.0 10.9 84.8 6.6 11.6 7.3 99.5 82.5 8.8 4.4 2.6 7.0 12.6 11.6 4.4 ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2;skeletal muscle: 29.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cardiomyocytes: 41.6;Syncytiotrophoblasts: 116.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.2;RPTEC TERT1: 1.5" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 7.0 2.3 8.7 0.3 8.5 0.0 3.9 7.2 11.7 2.3 10.4 3.9 0.6 2.0 1.3 1.3 5.6 0.7 24.5 8.2 8.2 6.6 31.2 2.1 0.3 8.3 8.5 5.1 9.4 5.0 2.6 1.1 8.1 5.2 0.7 1.5 2.3 1.5 29.2 1.1 2.5 0.2 7.8 1.8 11.0 1.7 8.7 0.3 2.7 31.3 0.3 4.4 1.8 8.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.3 0.0 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 8.7 8.5 7.2 11.7 8.2 8.2 8.3 8.5 8.1 7.8 8.7 8.5 1.5 9.6 20.1 76.4 1.8 1.0 4.1 2.7 3.4 1.7 4.6 4.6 41.6 14.3 9.6 9.2 10.4 8.8 6.5 1.0 11.7 1.5 0.5 2.5 1.6 3.3 3.6 2.5 8.3 0.6 0.9 5.3 8.6 2.5 8.8 6.1 6.1 27.1 2.5 0.0 13.2 2.0 4.1 2.1 2.8 1.6 23.9 2.1 0.0 14.0 2.0 7.6 6.2 21.6 19.2 0.9 5.8 27.1 3.0 3.5 4.1 14.8 14.3 8.5 0.0 7.8 5.2 0.5 0.6 1.9 1.0 116.4 10.0 2.5 2.4 2.5 ADPRS "ADPRHL2, ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylserine hydrolase" Q9NX46 1 36088892-36093932 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 79.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 51.6;Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA 54000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA026641: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" 19.0 36.7 28.4 16.0 30.0 19.7 18.5 31.3 30.3 20.7 33.4 19.6 15.6 17.6 15.0 36.1 33.5 13.3 20.7 28.6 29.1 27.7 22.4 20.6 21.5 32.5 29.7 19.7 17.9 17.6 17.7 20.8 31.2 19.9 12.4 9.1 20.9 16.3 34.4 34.1 16.8 16.4 31.9 23.1 17.6 28.7 29.7 20.9 19.4 21.8 20.2 21.3 22.2 33.9 54.3 22.4 26.2 37.2 23.6 17.1 37.3 39.4 32.9 62.1 60.9 26.8 47.7 38.4 37.5 39.5 32.0 32.9 33.4 60.5 37.0 27.7 41.8 34.9 27.0 36.3 44.4 40.2 19.9 20.3 45.4 56.5 24.5 47.2 39.9 36.2 30.8 30.9 29.6 26.0 40.9 60.5 56.5 31.8 46.0 32.9 27.6 38.8 56.5 43.8 32.1 50.8 28.9 29.9 65.9 34.4 30.9 34.3 27.6 35.7 37.0 50.1 53.0 39.8 41.2 34.2 51.7 39.6 22.4 40.6 58.3 65.8 43.4 74.1 41.5 43.5 47.6 50.8 71.4 51.5 47.7 40.3 57.1 47.9 77.7 44.8 43.4 57.8 28.4 30.0 31.3 30.3 28.6 29.1 32.5 29.7 31.2 31.9 29.7 33.9 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 79.2 6.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 40.7 6.4 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 70.6 1.3 0.0 0.0 0.0 AKIP1 "BCA3, C11orf17" ENSG00000166452 "A-kinase interacting protein 1" Q9NQ31 11 8911139-8920084 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061391 Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA061391: AB_2684499" "unprognostic (7.79e-3)" "unprognostic (5.65e-2)" "unprognostic (1.60e-1)" "prognostic favorable (5.15e-4)" "unprognostic (6.58e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (6.24e-9)" "unprognostic (1.03e-1)" "unprognostic (5.97e-2)" "unprognostic (5.77e-2)" "unprognostic (6.63e-2)" "unprognostic (8.88e-2)" "unprognostic (6.74e-3)" "unprognostic (1.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-3)" "unprognostic (1.19e-1)" 16.0 33.0 21.3 12.4 21.6 11.0 14.9 20.8 21.9 22.1 21.4 22.2 13.7 22.7 17.3 22.4 19.2 13.5 27.1 21.2 22.8 22.7 15.5 17.2 11.3 21.8 24.6 19.6 13.0 13.9 18.7 16.0 21.9 17.3 11.3 16.4 14.6 14.9 37.7 10.3 14.2 14.9 22.4 25.5 16.7 17.6 22.2 16.0 18.6 22.1 9.1 18.8 17.3 22.7 81.5 73.2 31.1 30.4 29.2 37.0 25.0 58.6 45.6 35.0 33.4 39.2 48.1 14.7 45.2 42.5 36.9 53.4 15.6 28.3 24.2 72.4 40.3 25.1 39.7 34.9 34.3 33.6 29.1 31.7 37.8 17.2 62.9 26.8 32.2 29.0 52.2 15.3 65.3 26.6 27.3 31.2 26.3 39.3 54.6 28.5 22.9 18.7 35.7 33.4 22.0 21.6 67.2 29.3 31.7 20.1 33.7 27.6 53.1 49.0 44.5 84.2 56.7 23.0 63.0 3.6 51.0 40.5 52.6 3.1 31.5 1.4 15.3 29.0 16.1 9.2 17.8 17.4 41.1 8.5 11.9 21.0 1.9 13.1 14.5 43.7 58.8 18.1 21.3 21.6 20.8 21.9 21.2 22.8 21.8 24.6 21.9 22.4 22.2 22.7 16.1 19.2 9.9 6.8 7.8 10.7 15.1 54.0 16.5 15.9 13.2 17.0 11.7 20.0 22.2 20.2 10.4 40.9 12.5 7.0 25.4 41.4 54.6 7.6 20.6 24.5 2.4 15.3 8.3 36.0 41.5 22.0 9.2 10.7 49.4 25.9 22.9 15.2 65.9 25.2 10.3 9.8 75.3 25.5 17.3 28.0 22.1 25.6 16.0 8.4 33.4 32.3 7.2 9.5 5.2 33.1 18.6 48.2 9.0 8.3 11.5 21.0 15.7 15.5 19.7 15.4 22.2 39.8 35.1 18.5 7.1 11.8 14.7 48.9 13.7 11.8 ALDH5A1 "SSADH, SSDH" ENSG00000112294 "Aldehyde dehydrogenase 5 family member A1" P51649 6 24494867-24537207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 98.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 136.6;U-698: 173.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029715, HPA029716" Enhanced Supported Mitochondria NA NA 50000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA029715: AB_10599994, HPA029716: AB_10601876" "unprognostic (7.43e-2)" "unprognostic (1.12e-3)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "prognostic favorable (7.61e-6)" "unprognostic (2.38e-2)" "unprognostic (2.17e-2)" "prognostic favorable (6.20e-4)" "unprognostic (1.43e-2)" "unprognostic (1.21e-1)" "prognostic favorable (3.68e-4)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-2)" "unprognostic (1.08e-2)" 9.4 6.1 27.8 5.9 28.9 4.4 5.2 25.0 32.7 5.4 18.8 8.5 11.8 4.8 3.7 7.3 19.0 5.1 14.5 26.5 32.8 27.8 98.8 6.4 13.6 26.7 35.0 7.3 8.2 19.4 5.8 2.4 27.3 8.2 7.1 11.0 5.2 5.2 57.9 9.5 8.0 3.1 29.4 6.8 7.7 4.5 34.0 26.8 17.0 33.8 12.9 6.7 8.4 24.9 11.5 9.3 6.5 10.1 0.1 0.0 11.7 0.8 2.0 2.4 1.6 35.1 2.5 136.6 21.1 1.0 2.2 0.1 10.5 1.3 1.5 14.7 20.2 20.7 5.9 42.4 1.6 32.2 2.7 1.0 4.4 0.2 0.0 7.1 0.1 34.7 10.4 0.0 1.8 23.3 40.4 19.0 2.7 18.4 5.5 46.1 1.4 1.3 7.7 19.6 11.7 10.5 12.1 1.2 13.2 2.8 19.4 17.5 0.2 1.1 6.7 0.3 7.1 19.4 32.2 173.7 0.2 9.8 1.4 0.3 0.0 0.1 1.0 0.0 1.9 2.2 1.4 1.5 0.1 2.0 3.8 3.4 0.2 0.8 0.1 2.4 0.9 0.7 27.8 28.9 25.0 32.7 26.5 32.8 26.7 35.0 27.3 29.4 34.0 24.9 2.9 16.0 25.3 14.0 9.7 1.7 5.6 8.2 2.2 12.9 7.5 3.4 34.8 11.5 9.4 7.3 16.7 6.1 7.4 6.1 1.9 1.6 0.8 15.2 5.0 3.7 8.4 16.0 18.1 1.0 5.2 3.5 5.6 5.4 7.0 13.5 6.8 90.7 3.9 16.8 32.4 11.7 2.0 3.8 1.8 0.3 3.4 1.7 1.8 8.4 0.2 11.8 3.1 11.6 2.4 1.3 7.7 4.5 12.2 4.1 13.4 26.8 12.8 6.9 0.0 6.9 2.3 1.7 6.6 8.7 3.0 1.9 5.4 8.0 17.0 13.1 ALKBH1 "ABH, alkB, ALKBH, hABH" ENSG00000100601 "AlkB homolog 1, histone H2A dioxygenase" Q13686 14 77672404-77708023 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, RNA repair, Translation regulation" "Dioxygenase, Lyase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044087, HPA060061" Approved Supported "Nucleoplasm,Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Endoplasmic reticulum" "HPA044087: AB_2678803, HPA060061: " "unprognostic (1.92e-2)" "unprognostic (8.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-3)" "unprognostic (3.41e-2)" "unprognostic (5.03e-2)" "unprognostic (3.74e-3)" "unprognostic (7.45e-3)" "unprognostic (2.68e-2)" "unprognostic (3.95e-2)" "unprognostic (5.05e-3)" "unprognostic (2.16e-2)" "prognostic favorable (1.80e-4)" "unprognostic (1.65e-3)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (2.44e-2)" 2.7 2.7 2.8 1.8 3.2 1.2 3.5 3.9 3.5 3.4 2.7 2.8 2.5 2.3 2.1 2.6 2.9 2.2 4.1 3.0 3.5 3.0 3.6 2.2 3.5 2.8 3.2 2.9 2.6 3.3 1.5 3.9 2.9 3.1 3.4 2.9 2.1 3.1 5.7 2.6 2.1 2.9 3.0 2.3 2.5 3.0 3.2 4.4 3.1 7.4 4.1 3.1 2.2 3.3 5.2 7.5 6.0 4.1 6.3 6.8 7.4 5.3 6.8 11.3 12.7 7.7 3.1 7.9 2.9 4.8 5.3 4.5 13.2 5.7 13.2 5.4 5.1 4.2 4.0 6.4 8.9 4.5 2.6 5.8 9.2 6.6 10.5 5.0 9.4 6.1 6.6 4.4 6.1 8.1 6.0 5.7 6.6 7.7 9.6 6.0 6.0 5.3 6.4 4.5 7.6 5.7 4.3 4.5 5.7 4.9 10.9 4.5 4.3 4.7 4.7 5.2 4.3 5.4 9.4 7.6 3.2 6.3 4.7 10.7 3.0 1.4 2.9 3.5 2.4 3.4 2.7 2.8 3.0 2.7 2.8 2.2 0.8 3.6 2.4 1.6 3.3 2.2 2.8 3.2 3.9 3.5 3.0 3.5 2.8 3.2 2.9 3.0 3.2 3.3 6.5 0.0 3.9 13.1 7.3 8.4 5.7 6.2 6.8 4.1 5.4 4.4 7.5 1.5 4.5 1.8 2.1 9.9 3.5 4.2 9.8 6.2 4.8 4.4 4.5 5.7 2.4 4.2 15.9 7.0 8.8 5.5 2.6 3.8 9.5 6.1 2.2 3.9 7.6 0.0 15.8 4.9 6.1 5.2 5.0 4.2 6.5 7.7 5.4 5.6 6.6 7.8 4.1 16.1 19.4 6.8 1.5 5.3 4.9 4.5 7.0 6.5 5.5 5.3 6.6 4.2 5.6 21.1 15.9 4.4 5.4 12.2 5.6 5.1 4.8 3.7 AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943331-95968720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7;skeletal muscle: 27.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 132.5" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 46.6;HMC-1: 47.7;Karpas-707: 61.2;SiHa: 40.5;SK-BR-3: 46.1;U-266/70: 49.1;U-266/84: 62.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" 1.8 11.7 8.2 6.5 11.2 6.1 0.4 5.5 11.8 0.3 6.9 1.4 5.1 3.0 0.4 2.6 0.7 1.7 1.7 7.6 6.9 5.8 60.7 2.3 4.4 15.5 8.6 1.4 3.3 0.7 0.5 2.0 9.5 2.8 0.2 1.8 2.0 0.2 27.3 5.8 5.0 0.6 2.7 5.9 4.8 13.1 8.0 0.6 0.9 0.9 0.4 0.3 0.2 15.4 46.6 9.5 0.8 5.8 0.0 0.0 10.0 1.5 0.5 0.7 1.4 3.9 5.8 4.0 4.2 0.0 2.6 8.2 0.3 0.0 0.3 16.0 1.7 4.2 7.9 9.4 0.0 5.9 47.7 0.0 0.4 0.8 0.1 0.2 0.3 3.9 2.7 61.2 0.0 6.8 3.7 10.8 4.4 1.8 2.2 7.8 0.3 5.3 0.0 4.3 4.9 6.9 40.5 46.1 5.2 0.2 4.6 8.4 0.0 5.8 19.1 8.0 5.4 49.1 62.8 6.3 3.8 12.2 6.9 0.2 0.6 1.7 0.5 0.6 0.4 0.6 0.2 0.6 0.5 0.3 0.3 0.4 0.4 2.3 1.8 0.2 0.1 0.5 8.2 11.2 5.5 11.8 7.6 6.9 15.5 8.6 9.5 2.7 8.0 15.4 1.1 0.0 0.5 0.3 2.0 0.4 0.2 0.0 0.0 0.1 1.1 1.0 0.6 1.5 0.6 3.7 0.0 0.9 1.7 0.0 3.9 0.2 0.9 0.1 0.0 0.8 1.8 8.0 0.7 1.1 0.1 0.1 0.0 0.0 0.0 0.2 8.6 132.5 4.4 1.7 0.3 0.1 0.0 5.7 1.3 0.1 0.3 1.8 3.6 0.0 0.7 1.8 2.1 4.0 2.0 0.2 0.0 0.0 0.7 0.0 0.4 31.0 0.0 0.0 0.0 0.8 0.0 1.5 1.9 0.0 0.3 0.3 1.4 0.3 0.4 0.1 ANAPC11 "APC11, Apc11p, HSPC214, MGC882" ENSG00000141552 "Anaphase promoting complex subunit 11" Q9NYG5 17 81890790-81900991 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1161.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA021989, HPA027838" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Nucleoli "HPA021989: AB_1844915, HPA027838: AB_10600978" "unprognostic (9.00e-3)" "unprognostic (1.24e-2)" "unprognostic (3.76e-1)" "unprognostic (4.93e-2)" "unprognostic (8.76e-2)" "unprognostic (1.67e-1)" "unprognostic (5.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.65e-1)" "unprognostic (2.17e-3)" "unprognostic (2.22e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "unprognostic (8.07e-2)" "unprognostic (9.08e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-1)" 112.1 120.5 104.8 52.1 108.6 109.3 103.4 110.9 149.5 85.9 100.7 126.0 61.0 86.4 39.0 125.8 80.3 58.0 231.3 106.4 106.8 127.3 185.7 89.3 73.0 110.0 105.1 76.4 108.1 59.0 92.0 54.8 105.0 105.7 27.3 19.3 117.6 42.0 272.8 99.7 83.4 36.5 110.4 86.7 117.9 189.7 113.0 50.1 90.6 126.5 34.0 95.9 94.7 118.1 262.4 605.0 139.0 209.7 118.7 132.8 164.3 123.4 100.6 111.4 127.1 248.6 226.9 82.1 133.3 114.4 121.8 148.9 58.1 166.4 40.5 122.5 437.1 126.8 257.9 379.0 131.3 95.3 103.6 145.6 151.8 120.4 98.2 73.4 184.9 111.9 173.7 233.8 120.8 474.1 225.5 150.6 131.2 259.2 448.7 92.3 136.2 168.0 104.9 229.3 175.8 282.6 133.5 205.7 253.8 96.7 254.1 222.7 108.4 215.0 169.5 229.4 234.1 110.5 52.1 107.0 228.7 144.5 177.7 495.1 419.8 418.8 229.7 359.9 218.7 309.0 232.0 252.9 348.0 296.2 223.0 212.3 212.1 258.5 345.4 581.1 297.9 506.0 104.8 108.6 110.9 149.5 106.4 106.8 110.0 105.1 105.0 110.4 113.0 118.1 137.2 128.2 157.2 11.4 110.5 148.6 215.0 406.1 145.7 59.5 272.5 332.7 360.2 201.6 272.3 198.6 20.9 467.8 119.5 239.6 522.3 260.6 451.9 157.0 151.3 152.9 190.3 201.6 9.8 337.7 524.6 182.9 124.4 169.5 108.3 158.3 159.2 496.4 448.2 33.7 10.2 272.6 319.4 174.6 194.3 1161.0 181.7 170.1 261.5 13.1 251.4 227.7 176.1 7.1 17.0 324.3 274.0 164.7 226.8 334.2 290.7 548.0 199.8 78.9 105.2 115.9 245.0 435.8 252.5 257.4 186.7 508.7 117.3 156.0 271.4 307.0 ANKRD46 ENSG00000186106 "Ankyrin repeat domain 46" Q86W74 8 100509752-100559784 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013758 Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA013758: AB_10962626" "unprognostic (3.71e-3)" "unprognostic (9.01e-2)" "unprognostic (2.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.82e-2)" "unprognostic (1.16e-1)" "unprognostic (2.63e-1)" "unprognostic (8.84e-2)" "unprognostic (4.79e-2)" "unprognostic (3.56e-1)" "unprognostic (2.98e-2)" "unprognostic (1.51e-1)" "unprognostic (8.08e-3)" "unprognostic (5.29e-2)" "unprognostic (1.82e-1)" "unprognostic (1.81e-2)" "unprognostic (6.29e-3)" 19.2 38.7 29.1 8.4 30.2 2.2 14.6 25.1 33.6 15.1 15.6 9.2 10.2 12.7 16.3 12.7 11.4 7.7 20.1 30.1 25.8 32.7 41.6 10.7 9.9 22.3 22.2 22.6 18.5 16.1 10.3 20.8 24.4 13.5 9.1 35.2 17.1 13.2 62.2 11.2 11.0 12.4 24.9 11.1 11.6 8.3 24.0 15.4 20.0 36.2 10.9 9.5 9.9 28.7 10.0 12.2 17.9 10.1 13.6 8.0 20.0 12.8 5.8 9.6 8.1 17.8 5.9 31.2 23.3 4.4 3.1 7.5 18.5 9.5 10.1 11.2 16.3 39.0 6.4 14.1 7.7 9.3 4.7 5.8 17.1 6.1 10.2 10.3 11.9 21.4 20.8 9.9 9.3 11.4 43.3 16.8 13.1 25.6 9.0 33.1 6.0 21.0 14.1 10.6 19.8 20.1 5.5 9.9 8.5 21.5 14.8 15.7 9.0 4.4 4.9 6.5 5.1 23.0 23.8 25.7 4.8 29.6 7.2 16.4 7.3 7.6 14.4 3.7 17.1 12.7 13.5 12.4 9.6 11.1 17.5 15.2 1.8 16.9 6.8 8.8 13.8 10.9 29.1 30.2 25.1 33.6 30.1 25.8 22.3 22.2 24.4 24.9 24.0 28.7 11.5 6.4 3.9 17.9 14.2 10.8 11.3 9.0 19.4 30.1 10.7 7.4 13.1 12.8 4.8 22.0 18.8 32.1 12.2 5.7 29.4 8.3 1.2 4.6 6.7 12.5 7.3 12.2 41.5 6.0 14.1 11.9 9.7 4.7 4.5 13.8 21.8 34.6 11.4 67.3 36.9 7.6 2.0 6.7 9.3 2.2 21.1 4.0 10.6 24.4 8.1 46.4 10.3 24.1 23.4 3.3 9.1 26.4 13.8 10.5 20.3 61.8 6.5 31.5 26.3 15.1 12.8 14.4 17.2 13.9 14.2 23.4 9.3 11.9 8.5 9.6 ANKRD52 "FLJ34236, PP6-ARS-C" ENSG00000139645 "Ankyrin repeat domain 52" Q8NB46 12 56237807-56258384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043815 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA043815: AB_10961762" "unprognostic (6.25e-3)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (2.67e-2)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.33e-4)" "unprognostic (9.84e-2)" "unprognostic (9.46e-2)" "unprognostic (5.43e-2)" "unprognostic (3.97e-3)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (1.27e-1)" "unprognostic (3.70e-2)" "unprognostic (6.31e-2)" 8.4 21.5 10.9 9.8 11.3 9.6 8.7 9.3 12.9 11.9 4.9 12.3 8.4 12.4 5.7 10.5 11.0 6.1 12.9 9.6 13.3 11.6 7.9 9.4 9.2 17.7 16.2 12.9 12.9 19.8 13.2 7.1 21.4 11.2 8.1 9.6 10.9 7.9 25.0 11.2 12.8 11.0 9.2 10.9 10.5 7.4 15.4 8.8 11.2 17.0 9.6 12.0 9.8 10.3 24.7 58.5 25.9 47.4 20.7 16.2 18.2 48.1 20.9 42.1 18.9 39.0 13.4 26.1 29.9 47.3 14.8 31.5 29.0 21.0 24.2 25.3 29.1 46.9 38.6 15.0 14.3 37.3 26.2 16.7 23.2 39.0 19.7 30.9 24.8 21.1 19.6 13.8 40.1 34.2 30.0 12.3 10.9 16.1 27.4 23.4 17.8 10.4 27.7 30.0 19.6 17.8 52.2 33.1 18.9 19.9 26.5 14.3 34.4 43.4 38.1 24.7 30.4 12.7 18.0 12.4 45.0 12.2 29.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.9 11.3 9.3 12.9 9.6 13.3 17.7 16.2 21.4 9.2 15.4 10.3 4.1 6.4 5.3 9.1 7.8 11.2 3.6 8.4 10.2 5.0 9.1 6.9 6.7 4.3 4.3 12.9 27.1 5.8 7.9 12.6 0.0 10.4 0.5 5.8 9.7 5.7 9.6 5.5 12.8 9.5 7.4 5.4 8.2 9.0 1.3 8.6 6.8 6.5 7.0 8.4 12.5 6.6 20.3 7.1 7.5 1.1 6.2 4.8 10.6 7.5 4.6 3.4 7.2 7.5 8.4 15.7 7.0 4.9 8.7 5.7 9.2 6.4 4.2 6.0 0.0 5.6 7.6 6.4 8.8 10.0 10.9 3.7 6.0 5.5 8.9 4.4 ANKRD9 ENSG00000156381 "Ankyrin repeat domain 9" Q96BM1 14 102501767-102509799 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 112.0;skeletal muscle: 154.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.8;Early spermatids: 161.0;Erythroid cells: 146.5;Proximal enterocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055985 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055985: AB_2682996" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (3.05e-2)" "unprognostic (1.26e-2)" "unprognostic (7.76e-2)" "unprognostic (7.31e-3)" "unprognostic (6.78e-2)" "unprognostic (3.97e-2)" "unprognostic (3.35e-1)" "unprognostic (2.99e-1)" "unprognostic (3.68e-1)" "unprognostic (1.17e-1)" "prognostic favorable (1.17e-7)" "unprognostic (3.89e-1)" "unprognostic (4.74e-1)" "unprognostic (1.32e-2)" "unprognostic (1.15e-1)" 12.1 21.1 29.0 3.0 20.8 18.1 10.4 22.2 43.1 10.5 27.4 30.7 50.3 7.6 1.9 19.5 6.9 4.6 112.0 19.0 17.5 24.2 16.0 15.9 0.8 36.4 24.3 10.2 11.4 8.8 7.4 5.0 27.4 20.1 10.0 2.4 26.1 4.1 154.7 25.6 32.7 2.4 27.4 9.2 22.5 40.6 37.3 0.4 11.2 26.4 1.7 12.9 15.0 15.3 16.0 7.5 13.3 12.6 13.6 5.6 20.8 18.7 7.0 8.3 8.1 1.9 10.5 0.0 20.5 5.2 9.2 25.8 6.5 3.8 4.2 11.3 26.7 4.2 14.7 3.6 7.0 1.5 13.5 2.8 22.6 4.5 4.5 5.4 3.6 2.1 8.2 1.4 4.0 14.0 2.2 4.4 6.3 24.6 33.5 21.5 12.5 1.0 8.5 16.2 10.8 11.5 13.3 8.6 24.4 7.8 13.1 6.0 8.3 8.4 10.9 41.4 14.7 11.9 6.9 0.5 9.9 2.9 8.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 29.0 20.8 22.2 43.1 19.0 17.5 36.4 24.3 27.4 27.4 37.3 15.3 10.8 19.2 4.5 41.4 2.7 13.0 37.5 1.5 6.8 11.0 32.3 22.5 40.3 15.7 5.0 14.7 2.1 9.7 30.4 198.8 92.0 3.9 161.0 11.4 6.4 9.8 16.7 146.5 12.6 4.8 30.5 13.5 34.7 21.5 31.8 20.1 8.6 11.8 29.5 16.8 14.1 42.5 2.0 7.5 7.8 23.9 5.6 25.4 10.6 5.6 0.7 16.8 2.1 4.0 3.4 5.3 73.7 9.8 10.2 37.8 129.2 16.7 1.1 7.7 13.1 26.8 10.8 6.6 6.7 14.1 20.2 18.3 9.3 18.3 56.7 54.8 AP3D1 ADTD ENSG00000065000 "Adaptor related protein complex 3 subunit delta 1" O14617 19 2100988-2164468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074408 Approved Cytosol No No 28000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA074408: AB_2686686" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.24e-3)" "unprognostic (1.37e-1)" "unprognostic (6.35e-2)" "prognostic unfavorable (9.23e-4)" "unprognostic (4.24e-2)" "unprognostic (8.05e-2)" "unprognostic (5.70e-2)" "unprognostic (6.68e-3)" "unprognostic (9.37e-2)" "prognostic favorable (2.61e-6)" "unprognostic (8.11e-3)" "unprognostic (1.22e-1)" "unprognostic (6.25e-2)" "unprognostic (1.73e-2)" 30.0 40.7 39.0 36.3 39.0 27.6 28.8 29.4 55.1 29.5 39.4 36.2 35.8 35.1 16.6 38.2 32.5 28.0 43.7 45.0 39.8 35.8 40.9 31.1 37.2 39.4 43.3 29.8 63.9 40.0 56.4 33.4 48.0 31.3 22.5 29.6 48.0 34.0 61.1 30.0 35.4 32.8 26.0 34.8 37.7 44.9 38.9 33.2 43.9 40.3 27.6 34.3 25.5 34.5 114.8 117.5 68.5 105.0 85.7 71.8 83.9 90.3 87.9 94.2 85.2 134.8 61.8 61.7 51.0 134.1 115.7 76.4 99.2 109.7 61.1 89.9 94.6 80.5 74.7 106.3 149.9 88.4 102.5 89.5 72.3 98.1 141.6 79.7 92.6 44.2 84.2 210.9 84.1 84.4 85.6 46.8 102.8 78.2 74.2 90.3 75.0 83.4 70.7 162.7 97.4 81.1 82.3 85.7 154.2 62.5 83.2 101.0 121.7 89.7 37.7 123.4 106.7 176.5 184.6 78.6 122.5 57.4 91.5 0.2 3.3 2.9 3.5 3.6 5.6 2.4 3.4 4.1 3.9 2.9 2.7 3.4 3.4 5.5 3.0 7.5 2.1 2.2 39.0 39.0 29.4 55.1 45.0 39.8 39.4 43.3 48.0 26.0 38.9 34.5 29.5 60.9 61.7 41.4 35.5 20.3 41.3 20.3 36.5 66.6 39.5 26.5 77.7 44.3 34.1 40.5 35.5 55.3 32.5 79.5 21.5 53.3 70.7 34.4 36.9 37.1 47.8 42.9 24.1 74.2 71.9 38.2 69.8 48.9 17.1 38.9 29.6 49.2 66.9 48.8 30.2 68.8 18.3 38.4 30.2 68.6 37.9 43.4 39.2 18.7 31.7 55.5 29.9 21.1 28.3 67.7 54.0 38.0 67.6 65.5 52.6 36.0 30.3 43.9 19.7 37.8 33.6 105.3 129.5 38.0 23.3 78.0 36.9 39.6 56.8 59.4 AP5S1 "C20orf29, FLJ11168" ENSG00000125843 "Adaptor related protein complex 5 subunit sigma 1" Q9NUS5 20 3820524-3828838 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034200, HPA043533, HPA048244" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB034200: AB_1564201, HPA043533: AB_2732507, HPA048244: AB_2680328" "unprognostic (1.07e-2)" "unprognostic (1.43e-1)" "unprognostic (8.52e-2)" "unprognostic (2.74e-2)" "unprognostic (1.34e-1)" "unprognostic (2.05e-2)" "unprognostic (5.49e-2)" "unprognostic (7.76e-2)" "unprognostic (1.33e-1)" "unprognostic (8.91e-2)" "unprognostic (5.15e-3)" "unprognostic (8.17e-2)" "prognostic favorable (5.53e-5)" "unprognostic (2.92e-1)" "unprognostic (1.62e-1)" "unprognostic (6.09e-3)" "unprognostic (5.08e-2)" 6.0 11.5 7.1 5.5 7.7 7.4 5.8 6.4 8.2 4.8 8.1 6.2 6.3 5.7 3.0 7.4 4.7 4.6 11.3 7.3 6.7 9.4 14.6 5.4 5.5 6.8 6.5 5.8 7.5 7.8 7.5 5.4 6.5 6.9 4.4 3.4 8.7 3.6 19.2 5.3 6.4 3.9 6.3 8.2 6.4 11.2 6.6 4.3 9.4 10.0 3.8 5.4 5.1 6.5 18.1 33.8 4.6 3.1 6.2 8.0 5.7 10.8 8.6 10.4 8.3 28.5 18.9 10.4 11.3 11.4 19.7 15.9 3.9 17.4 3.6 5.7 10.9 17.3 10.1 25.3 10.7 12.0 10.0 13.7 9.7 13.0 10.3 7.0 12.4 12.4 12.4 19.8 14.0 29.4 28.0 10.5 4.2 13.0 27.3 11.7 7.8 10.8 11.8 14.4 14.2 5.7 10.6 32.4 18.2 3.1 15.9 5.9 16.9 21.7 10.3 11.3 20.6 10.6 12.6 5.7 7.5 10.6 19.0 2.2 7.5 4.6 10.2 11.9 7.8 5.4 8.5 8.4 9.9 7.0 7.8 7.3 1.7 6.2 6.7 7.7 9.9 6.5 7.1 7.7 6.4 8.2 7.3 6.7 6.8 6.5 6.5 6.3 6.6 6.5 4.0 0.0 10.6 2.3 5.9 1.7 4.4 8.0 7.4 15.3 4.9 4.3 11.2 11.5 5.9 3.7 10.4 19.4 3.8 8.4 11.7 11.1 3.7 5.1 6.2 8.6 12.6 9.9 1.9 12.7 13.3 6.8 14.8 5.2 14.0 6.6 6.1 9.4 15.5 25.2 2.1 7.3 8.2 6.9 2.0 3.6 5.9 7.3 5.4 4.7 11.0 12.8 8.2 2.5 1.7 10.2 8.8 4.1 8.6 3.6 11.2 8.5 4.5 20.8 13.1 5.8 4.5 19.4 10.9 6.8 1.0 18.5 6.2 10.9 7.4 3.0 APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" 9.0 23.7 55.8 9.0 58.0 7.9 13.3 58.1 76.3 13.1 67.8 17.3 14.4 10.6 19.6 12.6 20.8 9.3 65.1 57.9 58.4 46.5 18.2 8.6 11.7 58.8 57.0 9.4 14.2 62.0 29.2 10.9 57.3 13.7 18.8 52.8 19.7 15.0 45.9 7.7 12.0 12.0 57.0 8.4 17.7 16.8 56.8 14.0 20.3 73.2 11.6 11.2 8.1 57.1 36.5 32.7 53.9 37.8 8.8 19.9 8.3 17.9 21.9 37.4 38.8 19.3 17.0 31.5 21.9 16.5 48.5 29.3 68.5 35.7 41.2 33.4 48.7 15.9 28.6 31.1 20.8 40.9 17.1 22.2 20.7 41.2 30.4 20.1 26.6 38.8 22.9 33.2 35.1 34.6 41.2 43.0 49.2 47.5 52.7 31.5 26.6 75.6 74.1 18.4 36.4 26.5 39.0 36.7 39.7 52.4 63.6 17.9 6.5 23.9 14.6 86.6 27.9 26.3 50.5 28.7 38.5 19.8 35.8 14.8 4.8 1.4 12.6 15.9 16.6 10.8 13.7 12.5 14.0 10.2 10.9 10.7 3.0 10.3 16.0 16.6 14.0 7.7 55.8 58.0 58.1 76.3 57.9 58.4 58.8 57.0 57.3 57.0 56.8 57.1 7.4 16.0 11.5 61.7 11.8 14.0 17.0 74.3 11.4 20.4 14.3 17.0 61.8 21.5 28.3 23.9 14.6 17.2 11.3 12.8 180.0 28.4 25.9 56.0 13.0 10.1 7.2 20.8 61.4 16.0 8.9 11.7 13.3 24.4 3.8 14.2 7.9 13.9 22.7 20.2 76.5 17.0 44.7 14.6 12.0 15.7 11.5 9.9 28.4 74.0 34.2 50.0 8.2 43.7 76.5 10.2 20.0 15.8 14.8 14.1 24.0 80.6 106.9 32.4 6.6 10.8 22.3 26.1 53.2 18.9 7.0 12.4 9.5 17.0 22.3 16.8 ARL6IP4 "SFRS20, SR-25, SRp25, SRrp37" ENSG00000182196 "ADP ribosylation factor like GTPase 6 interacting protein 4" Q66PJ3 12 122980060-122982913 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052098 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Mitochondria "HPA052098: AB_2681724" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" "unprognostic (8.42e-3)" "unprognostic (1.86e-1)" "unprognostic (4.23e-2)" "unprognostic (2.04e-3)" "unprognostic (6.48e-4)" "unprognostic (1.06e-2)" "unprognostic (1.38e-1)" "unprognostic (8.62e-2)" "unprognostic (3.03e-5)" "unprognostic (4.01e-2)" "unprognostic (8.41e-8)" "unprognostic (6.84e-2)" "unprognostic (2.16e-1)" "unprognostic (1.43e-2)" "prognostic favorable (1.08e-4)" 134.0 168.4 158.3 88.5 152.0 162.6 130.6 147.5 178.3 135.7 143.1 177.2 108.8 117.1 63.7 118.3 120.5 74.9 190.3 148.9 151.2 159.1 207.4 106.9 117.9 157.2 157.9 142.4 192.6 109.3 120.4 67.3 156.4 131.4 59.2 44.1 151.8 92.6 373.4 118.0 116.0 64.1 149.0 135.5 161.1 91.3 158.1 100.6 114.8 174.0 82.5 145.8 117.5 161.1 233.9 248.5 160.3 108.3 110.3 144.7 125.7 131.0 156.0 192.5 145.4 123.9 96.2 220.5 160.3 166.8 90.1 120.3 129.1 212.6 85.2 197.1 134.8 367.3 227.3 246.5 211.4 202.8 155.6 151.0 168.3 148.4 193.7 210.1 214.8 174.6 166.4 104.3 156.2 274.1 237.5 367.4 126.5 140.1 156.0 178.1 175.9 262.6 168.2 195.1 155.1 185.2 123.7 204.3 314.5 69.6 268.4 259.5 194.5 110.7 202.4 106.6 166.1 221.6 115.0 255.4 159.9 233.8 141.6 182.2 250.1 266.6 194.6 327.5 209.3 241.1 231.4 217.0 315.8 233.8 219.7 198.4 68.5 216.9 385.2 215.0 272.3 298.5 158.3 152.0 147.5 178.3 148.9 151.2 157.2 157.9 156.4 149.0 158.1 161.1 239.4 93.0 127.9 33.6 228.0 204.4 313.8 271.4 156.5 111.1 309.0 379.5 0.0 207.3 146.2 211.5 43.8 282.2 262.0 361.9 516.5 306.3 200.5 141.3 168.6 218.7 223.3 147.5 27.1 635.5 261.0 197.4 171.8 112.1 167.1 273.3 240.2 465.6 386.5 97.6 26.5 332.6 170.9 401.4 412.8 380.8 222.4 270.7 377.1 23.4 477.6 231.0 324.4 18.6 26.4 395.6 332.8 180.9 241.6 337.3 706.6 814.9 135.8 125.5 177.5 215.3 242.7 189.1 164.2 188.8 203.3 240.2 228.5 353.8 331.7 370.1 ARPC5L "ARC16-2, MGC3038" ENSG00000136950 "Actin related protein 2/3 complex subunit 5 like" Q9BPX5 9 124862130-124877733 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 576.3;Late spermatids: 975.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 415.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022013 Approved NA NA 97000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" "HPA022013: AB_1845045" "unprognostic (2.10e-1)" "unprognostic (3.40e-1)" "unprognostic (2.91e-3)" "unprognostic (2.59e-2)" "unprognostic (9.04e-3)" "unprognostic (1.25e-1)" "unprognostic (4.42e-3)" "unprognostic (2.48e-2)" "unprognostic (9.37e-2)" "unprognostic (6.80e-2)" "unprognostic (4.30e-1)" "unprognostic (2.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.99e-2)" "unprognostic (4.35e-1)" "unprognostic (7.55e-3)" "unprognostic (3.58e-1)" 40.1 60.3 47.3 27.6 50.6 51.9 32.7 46.2 57.5 29.7 41.9 38.6 25.5 23.8 22.7 90.7 21.0 19.3 63.0 51.7 49.2 59.0 59.6 47.6 44.6 47.2 47.3 15.1 28.4 22.7 44.1 24.2 47.8 27.8 26.1 14.4 37.3 16.9 70.4 69.8 34.4 18.1 45.6 57.7 43.6 79.1 48.9 24.4 27.8 41.5 48.4 34.0 46.5 50.0 86.2 45.5 38.3 44.9 31.6 45.6 93.5 87.5 48.1 65.9 46.0 94.2 72.9 78.3 51.4 53.5 48.4 124.2 60.4 77.2 62.1 86.8 47.1 41.3 109.5 55.7 50.6 90.8 50.6 35.6 91.1 58.6 63.8 40.4 76.5 47.4 112.0 209.3 69.8 125.3 52.3 86.8 90.1 134.8 114.3 83.2 66.3 228.1 64.2 59.9 56.0 45.3 58.6 74.6 75.5 41.9 105.4 89.0 85.0 55.1 64.7 81.9 123.3 138.0 415.8 103.7 65.3 69.0 53.2 10.2 15.5 20.7 73.3 13.7 71.7 67.3 43.3 77.5 27.1 64.6 31.8 50.3 8.7 86.5 16.1 54.4 54.8 24.3 47.3 50.6 46.2 57.5 51.7 49.2 47.2 47.3 47.8 45.6 48.9 50.0 79.4 57.7 64.4 5.2 98.7 354.2 149.9 135.5 101.3 25.6 92.5 79.4 80.5 71.4 90.8 68.0 2.1 152.2 143.9 104.9 131.0 126.9 576.3 79.8 38.4 119.5 65.7 37.6 17.4 164.6 163.9 49.0 69.8 78.7 37.4 42.6 75.0 83.5 95.2 25.2 10.9 83.8 101.7 32.1 147.3 975.1 41.3 48.9 90.7 5.6 55.7 72.3 267.7 6.0 9.9 270.2 92.5 48.5 150.8 182.0 77.2 98.2 77.5 25.6 26.3 31.3 71.1 246.1 124.3 156.4 418.5 213.7 137.2 66.5 99.9 267.8 ARPIN-AP3S2 C15orf38-AP3S2 ENSG00000250021 "ARPIN-AP3S2 readthrough" 15 89834308-89912882 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA040513, HPA047173, HPA049270, HPA052278" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" Vesicles "HPA040513: AB_2677015, HPA047173: AB_2679969, HPA049270: AB_2680696, HPA052278: AB_2681783" "unprognostic (1.27e-1)" "unprognostic (8.88e-2)" "unprognostic (4.94e-2)" "unprognostic (1.04e-1)" "unprognostic (3.25e-2)" "unprognostic (3.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.84e-1)" "unprognostic (2.19e-1)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (8.35e-2)" "unprognostic (2.29e-1)" "unprognostic (4.49e-2)" 12.3 12.8 12.4 7.9 14.1 5.9 11.5 14.5 13.3 9.2 10.7 14.6 10.4 9.1 11.4 12.8 9.1 8.1 19.4 11.2 14.2 13.9 23.4 10.2 5.8 14.6 15.1 10.6 20.3 10.9 10.2 9.3 15.0 11.0 15.0 10.9 10.3 8.7 22.0 10.3 9.6 9.4 13.2 9.5 9.4 12.0 15.0 9.0 11.2 15.2 8.0 11.0 10.0 14.9 11.7 25.0 19.5 26.1 27.7 12.5 13.9 20.3 22.8 25.5 25.5 8.1 26.8 6.2 20.8 17.1 21.6 14.2 15.9 17.8 17.2 12.6 14.7 8.6 11.2 18.4 16.1 4.2 6.6 15.2 14.7 15.1 15.2 13.8 23.0 7.5 8.3 14.4 19.8 16.6 6.4 7.0 20.2 29.7 6.0 5.0 7.7 4.1 24.4 13.3 6.1 9.9 36.3 35.2 27.9 25.1 23.3 8.9 11.8 22.6 16.8 31.4 13.0 4.6 13.0 6.6 19.1 5.6 17.0 13.1 26.7 11.8 6.8 23.1 9.1 7.2 8.4 7.5 20.0 6.8 6.2 6.2 18.7 10.9 16.8 8.4 9.3 16.9 12.4 14.1 14.5 13.3 11.2 14.2 14.6 15.1 15.0 13.2 15.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARV1 ENSG00000173409 "ARV1 homolog, fatty acid homeostasis modulator" Q9H2C2 1 230978981-231000733 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035709 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA035709: AB_2674744" "unprognostic (2.32e-1)" "unprognostic (4.69e-2)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-1)" "unprognostic (1.42e-1)" "unprognostic (9.95e-2)" "unprognostic (5.66e-2)" "prognostic favorable (3.27e-5)" "unprognostic (1.37e-1)" "unprognostic (1.12e-2)" "unprognostic (9.57e-2)" "unprognostic (9.82e-2)" "unprognostic (2.31e-1)" "unprognostic (4.82e-1)" "unprognostic (5.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.12e-3)" 10.6 18.4 23.4 10.2 24.5 13.9 19.0 26.2 32.8 12.2 25.7 24.6 16.4 9.7 22.9 15.7 14.3 16.4 30.1 24.5 25.6 25.2 26.2 15.0 14.8 25.2 24.1 11.2 17.5 33.3 20.1 11.7 25.0 16.2 25.9 29.0 22.0 15.2 21.7 17.8 17.3 13.1 25.7 13.5 17.1 31.3 25.2 15.0 21.9 24.8 15.3 15.2 11.2 27.7 40.8 43.6 20.8 25.1 29.6 26.4 20.1 19.0 34.0 33.5 38.3 16.3 31.4 11.4 22.7 21.3 20.5 32.3 40.6 25.5 39.2 30.4 55.7 36.8 28.9 22.1 30.5 53.6 27.9 28.0 25.8 18.1 20.9 21.9 22.5 34.7 53.7 30.7 22.2 14.3 22.3 16.4 27.1 43.0 27.1 25.2 32.1 33.1 47.1 33.0 21.2 32.6 22.6 26.6 57.9 5.3 46.6 46.6 13.9 13.4 8.7 23.6 45.9 47.4 44.6 28.9 36.8 45.9 36.7 9.1 8.1 8.5 10.0 12.2 13.9 18.1 11.2 12.4 10.1 11.2 13.7 13.0 2.0 12.7 21.2 14.9 15.4 9.0 23.4 24.5 26.2 32.8 24.5 25.6 25.2 24.1 25.0 25.7 25.2 27.7 13.6 16.0 31.7 10.7 12.6 12.9 22.0 75.8 11.4 18.9 14.8 15.6 32.2 21.5 38.9 29.5 2.1 37.9 12.7 15.8 60.7 24.1 52.6 12.7 10.9 12.7 7.7 58.1 20.2 40.8 14.5 14.5 11.7 9.7 17.1 14.4 15.0 17.3 24.9 38.7 25.6 18.5 34.6 13.3 5.5 22.9 9.3 13.5 24.9 8.4 9.8 33.6 7.2 8.5 19.3 21.5 11.5 16.6 14.7 11.6 17.9 32.5 27.3 20.0 0.0 11.4 15.6 116.7 21.0 20.3 15.2 15.6 11.4 22.0 26.4 20.9 ASB18 ENSG00000182177 "Ankyrin repeat and SOCS box containing 18" Q6ZVZ8 2 236194872-236264409 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;heart muscle: 7.4;skeletal muscle: 11.3" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 6.5;Excitatory neurons: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068447 Approved Nucleoli,Mitochondria NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "HPA068447: AB_2685991" "unprognostic (1.12e-1)" "unprognostic (7.33e-3)" "unprognostic (3.07e-1)" "unprognostic (1.78e-6)" "unprognostic (4.75e-2)" "unprognostic (3.22e-1)" 0.0 0.0 0.6 0.0 4.8 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1.0 0.6 0.0 0.0 0.0 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 1.5 0.0 0.0 0.5 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 4.8 1.0 1.0 1.0 0.6 2.3 2.0 1.4 1.5 3.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ASB4 ASB-4 ENSG00000005981 "Ankyrin repeat and SOCS box containing 4" Q9Y574 7 95478444-95540233 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 47.1;skeletal muscle: 34.2" "Cell type enhanced" "Detected in some" "Astrocytes: 7.2;Cardiomyocytes: 3.2;Early spermatids: 2.3;Late spermatids: 2.0;Respiratory ciliated cells: 2.0" "Cancer enhanced" "Detected in some" "stomach cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.9;Hep G2: 7.9;SCLC-21H: 4.7" "Group enriched" "Detected in many" 4 "basal ganglia: 9.5;hypothalamus: 31.7" "Region enriched" "Detected in single" 10 "midbrain: 4.3" HPA055240 Uncertain NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "HPA055240: AB_2682753" "unprognostic (1.41e-1)" "unprognostic (3.67e-1)" "unprognostic (1.88e-2)" "unprognostic (2.66e-1)" "unprognostic (3.71e-1)" "unprognostic (2.85e-3)" "unprognostic (1.17e-1)" "unprognostic (3.55e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (2.92e-2)" "unprognostic (4.24e-1)" "unprognostic (9.13e-7)" "unprognostic (1.71e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-1)" "unprognostic (7.23e-2)" 0.1 47.1 1.8 0.2 2.3 0.6 0.4 2.3 2.1 0.1 1.5 0.1 0.3 0.1 0.2 0.3 0.3 0.2 1.9 1.8 2.4 0.2 1.5 0.6 0.3 2.5 3.8 0.2 0.7 0.0 8.4 2.1 2.6 0.2 0.1 1.3 0.6 0.2 34.2 0.3 0.4 0.1 1.8 0.3 0.6 0.3 2.2 0.2 0.3 10.5 0.1 0.0 0.0 2.8 0.2 4.9 0.2 1.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.8 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.7 0.1 0.1 0.0 0.1 0.1 4.7 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.4 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.3 2.3 2.1 1.8 2.4 2.5 3.8 2.6 1.8 2.2 2.8 0.1 0.0 0.5 7.2 0.0 0.1 0.1 0.5 0.0 0.0 0.4 0.1 3.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 2.0 0.6 0.0 0.0 1.0 0.0 0.0 1.0 1.0 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.4 2.0 0.0 0.0 0.7 0.1 0.9 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.1 ASCC1 "ASC1p50, CGI-18, Em:AC022392.3, p50" ENSG00000138303 "Activating signal cointegrator 1 complex subunit 1" Q8N9N2 10 72096032-72217134 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038038, HPA057567" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "HPA038038: AB_10674544, HPA057567: " "unprognostic (1.96e-1)" "unprognostic (2.79e-2)" "unprognostic (5.36e-2)" "unprognostic (1.03e-2)" "unprognostic (2.92e-3)" "unprognostic (2.34e-2)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.22e-2)" "unprognostic (8.30e-3)" "unprognostic (3.22e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.34e-2)" "unprognostic (1.74e-1)" "unprognostic (2.66e-1)" "unprognostic (6.64e-2)" 19.0 24.9 18.3 13.9 23.5 7.3 16.4 22.4 24.5 16.1 18.8 14.4 9.0 17.1 16.4 14.3 15.3 13.7 24.8 17.2 20.7 15.2 21.6 13.5 18.5 23.4 20.6 17.9 22.7 14.2 11.9 13.0 23.6 11.9 9.9 15.7 12.8 14.5 29.7 17.1 14.6 12.4 21.7 17.1 14.4 18.4 20.4 22.3 13.4 17.3 16.8 15.7 13.6 30.4 29.3 40.3 25.8 58.1 34.0 37.9 21.1 18.0 33.5 26.5 30.7 31.4 105.3 37.0 35.6 26.3 17.9 38.4 21.1 30.6 26.5 27.2 20.1 24.1 29.1 36.4 32.7 25.2 24.1 33.3 68.9 26.7 45.0 38.1 36.4 40.4 34.8 51.8 35.0 25.7 34.2 36.1 15.7 18.8 8.8 20.1 21.1 27.4 49.8 21.0 27.1 16.9 26.1 65.7 49.4 23.9 21.7 18.5 32.0 15.2 27.1 11.6 19.4 28.4 40.4 45.5 24.6 55.9 10.8 20.4 19.0 35.0 16.5 20.3 17.0 31.4 19.4 17.7 21.0 32.5 27.2 25.8 12.5 26.6 15.4 28.9 29.2 19.0 18.3 23.5 22.4 24.5 17.2 20.7 23.4 20.6 23.6 21.7 20.4 30.4 16.7 9.6 5.8 25.5 20.5 6.2 14.0 22.8 9.6 12.9 9.0 6.3 23.6 10.0 13.4 12.9 14.6 17.7 18.6 4.7 23.5 20.4 27.5 12.1 13.8 13.9 3.6 11.1 33.1 20.0 19.5 16.5 6.6 12.1 12.7 12.6 10.4 22.0 18.2 25.2 42.9 5.2 16.2 24.1 8.7 14.2 20.5 12.7 19.6 27.2 21.4 19.9 16.5 35.7 52.8 14.7 8.4 20.7 14.5 8.0 9.5 11.4 9.8 14.3 13.1 10.8 15.9 27.8 28.2 10.9 7.0 15.2 17.9 18.9 6.5 9.2 ATP5F1E ATP5E ENSG00000124172 "ATP synthase F1 subunit epsilon" P56381 20 59025475-59032345 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 3414.2;Hofbauer cells: 2765.4;Proximal tubular cells: 4125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.73e-1)" "unprognostic (6.30e-2)" "unprognostic (8.16e-2)" "unprognostic (9.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.92e-3)" "unprognostic (7.88e-3)" "unprognostic (2.51e-1)" "unprognostic (5.01e-2)" "unprognostic (6.41e-2)" "unprognostic (4.35e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (3.98e-1)" "unprognostic (3.21e-1)" "unprognostic (1.67e-1)" "unprognostic (2.44e-2)" 81.4 88.3 92.2 98.5 94.5 125.6 62.3 95.3 135.8 49.3 95.7 77.2 80.1 51.2 25.3 77.0 45.2 13.9 162.8 92.7 95.7 128.5 80.2 69.3 69.8 94.2 94.0 42.1 44.9 52.9 104.8 34.0 94.4 50.6 33.1 42.8 62.7 23.7 240.1 42.8 78.9 25.6 95.4 93.5 69.5 47.7 93.7 64.7 64.1 107.0 40.0 63.4 55.5 97.1 150.0 49.6 98.1 90.0 94.0 87.2 65.2 155.9 60.6 102.2 66.0 156.3 143.5 81.1 184.7 82.7 159.6 141.5 70.3 123.7 67.0 66.7 76.4 271.4 107.2 136.5 86.4 193.2 234.6 95.0 105.3 62.5 77.8 99.8 76.9 107.6 103.6 113.8 59.4 144.4 247.8 299.1 32.9 220.4 203.4 120.2 138.3 156.8 107.5 83.0 98.0 146.6 261.6 273.9 328.4 83.5 182.5 312.8 264.3 208.3 222.0 138.9 213.7 180.2 245.9 238.1 201.5 117.9 117.1 613.1 420.6 757.3 237.5 463.8 224.9 351.4 285.8 268.7 356.0 291.7 227.8 259.4 713.9 243.1 470.7 601.7 393.3 781.7 92.2 94.5 95.3 135.8 92.7 95.7 94.2 94.0 94.4 95.4 93.7 97.1 1036.3 516.0 530.8 0.0 331.5 0.0 0.0 0.0 0.0 0.0 1042.4 1138.3 0.0 0.0 289.7 1121.9 0.0 705.8 812.6 0.0 3414.2 998.0 0.0 1145.2 1007.1 436.6 0.0 0.0 0.0 1202.6 956.9 341.7 0.0 1410.3 352.0 594.0 0.0 0.0 2765.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.4 0.0 0.0 1473.1 0.0 0.0 0.0 0.0 1427.7 0.0 0.0 132.5 0.0 0.0 4125.3 392.8 0.0 0.0 0.0 334.0 0.0 0.0 0.0 0.0 590.5 431.2 731.9 0.0 0.0 ATP5MC1 "ATP5G, ATP5G1" ENSG00000159199 "ATP synthase membrane subunit c locus 1" P05496 17 48892765-48895871 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1296.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 387.6;Distal tubular cells: 1449.8;Proximal tubular cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 2026.7" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "unprognostic (3.43e-2)" "prognostic favorable (3.88e-4)" "unprognostic (6.60e-2)" "unprognostic (2.09e-1)" "unprognostic (8.73e-2)" "unprognostic (4.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.53e-1)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (9.42e-3)" "unprognostic (9.78e-2)" "prognostic favorable (8.24e-6)" "unprognostic (2.07e-2)" "unprognostic (5.60e-2)" "unprognostic (1.95e-1)" "unprognostic (2.33e-1)" 99.1 160.4 210.3 97.5 218.8 116.5 134.1 230.6 265.5 101.7 218.0 359.5 215.2 113.2 179.8 197.7 121.4 58.8 764.0 221.0 230.8 284.4 258.2 81.4 103.5 219.4 211.3 88.4 117.3 268.3 125.6 82.4 217.5 101.2 344.4 117.1 127.1 118.4 874.7 130.9 187.1 149.9 213.2 99.0 195.4 47.2 220.7 129.5 133.2 1296.3 173.1 113.9 118.7 213.2 477.3 631.0 196.6 287.1 212.4 257.7 284.6 257.0 214.9 334.5 329.8 415.1 333.9 514.1 597.5 224.2 357.5 422.5 353.9 449.8 496.5 434.6 475.0 507.8 379.7 848.2 148.9 611.0 244.4 209.4 302.3 353.7 393.3 180.4 384.8 420.5 305.4 344.4 393.5 484.9 586.6 285.5 122.5 2026.7 617.4 364.0 511.3 832.9 645.8 266.7 290.8 210.7 192.0 409.1 227.3 296.6 602.2 411.3 214.2 210.3 288.3 322.3 333.1 309.0 382.7 706.8 302.5 476.7 255.7 75.4 328.5 91.8 193.7 299.5 236.9 463.9 220.0 209.5 448.5 375.2 293.6 253.9 18.2 270.6 179.2 555.2 211.7 341.6 210.3 218.8 230.6 265.5 221.0 230.8 219.4 211.3 217.5 213.2 220.7 213.2 139.6 48.1 87.9 0.0 43.2 0.0 0.0 0.0 0.0 0.0 214.6 312.5 0.0 0.0 49.5 274.0 0.0 387.6 48.6 0.0 1449.8 185.5 0.0 101.4 144.9 61.6 0.0 0.0 0.0 298.1 283.3 82.6 0.0 126.3 73.2 129.8 0.0 0.0 270.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.9 0.0 0.0 72.4 0.0 0.0 0.0 0.0 196.4 0.0 0.0 11.4 0.0 0.0 913.9 53.2 0.0 0.0 0.0 74.6 0.0 0.0 0.0 0.0 222.3 36.5 327.9 0.0 0.0 ATP5MD "bA792D24.4, DAPIT, MGC14697, USMG5" ENSG00000173915 "ATP synthase membrane subunit DAPIT" Q96IX5 10 103389041-103396492 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1340.2;Ductal cells: 705.9;Exocrine glandular cells: 723.1;Pancreatic endocrine cells: 884.5;Proximal tubular cells: 1879.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044798 Supported Mitochondria NA NA 55000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA044798: AB_2679091" "unprognostic (4.41e-2)" "unprognostic (3.08e-2)" "unprognostic (2.59e-1)" "unprognostic (7.93e-2)" "unprognostic (1.65e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (1.57e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (7.46e-2)" "unprognostic (1.03e-2)" 332.3 343.0 502.9 155.1 517.7 193.0 324.6 514.9 721.8 215.1 515.2 484.6 273.5 176.9 410.2 426.1 194.3 140.8 1229.7 526.1 539.0 546.7 587.1 215.3 180.3 501.2 501.9 157.5 321.4 519.2 309.2 157.4 506.1 254.2 449.6 245.3 234.8 236.4 1019.3 204.6 261.7 229.8 511.8 185.4 369.8 142.5 509.3 319.0 191.2 1325.5 251.0 284.7 258.9 518.0 557.8 559.4 528.4 648.2 570.2 696.0 348.3 523.2 612.7 501.0 556.6 925.2 605.3 312.4 288.9 575.3 398.6 559.4 502.2 522.7 697.9 414.7 887.3 331.8 682.1 1057.7 545.7 688.3 491.3 569.2 801.1 456.4 715.7 849.2 661.5 470.0 441.5 517.5 849.4 842.0 552.0 1167.5 397.8 830.1 959.1 355.8 326.0 495.3 1218.4 878.4 203.7 464.8 269.4 419.7 824.9 723.5 373.4 619.9 388.6 255.2 394.2 394.0 692.8 537.2 958.4 543.5 545.2 678.2 200.3 575.3 271.2 395.8 214.7 384.0 248.0 301.6 296.3 259.8 314.1 219.1 251.4 256.7 231.1 230.5 375.3 456.3 307.9 304.4 502.9 517.7 514.9 721.8 526.1 539.0 501.2 501.9 506.1 511.8 509.3 518.0 169.1 211.5 173.2 0.0 40.9 0.0 0.0 0.0 0.0 0.0 323.4 417.6 0.0 0.0 91.0 388.1 0.0 298.0 76.3 0.0 1340.2 705.9 0.0 406.0 245.4 114.5 0.0 0.0 0.0 723.1 439.4 81.8 0.0 424.5 118.6 176.9 0.0 0.0 543.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.4 0.0 0.0 432.6 0.0 0.0 0.0 0.0 884.5 0.0 0.0 0.0 0.0 0.0 1879.7 121.0 0.0 0.0 0.0 127.9 0.0 0.0 0.0 0.0 305.8 69.4 209.9 0.0 0.0 ATP5ME ATP5I ENSG00000169020 "ATP synthase membrane subunit e" P56385 4 672436-674330 "Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2048.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 886.5;Distal tubular cells: 1729.5;Proximal tubular cells: 2485.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035010 Enhanced Supported Mitochondria NA NA 280000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA035010: AB_10669853" "unprognostic (1.42e-1)" "unprognostic (4.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (3.44e-1)" "unprognostic (1.23e-1)" "unprognostic (6.95e-2)" "unprognostic (7.92e-2)" "unprognostic (3.32e-1)" "unprognostic (1.35e-3)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (2.46e-3)" "unprognostic (6.89e-2)" "unprognostic (2.18e-1)" "unprognostic (2.48e-1)" "unprognostic (6.45e-3)" 360.1 412.7 940.1 212.2 960.8 312.4 277.4 981.5 1172.2 263.3 926.5 555.7 460.3 237.4 242.7 511.9 218.8 94.5 1507.7 932.5 968.9 572.0 591.7 235.6 174.6 980.1 955.6 257.5 330.9 774.8 312.8 144.8 972.5 262.0 331.4 336.4 304.8 220.4 2048.3 297.8 436.7 172.8 952.6 281.3 414.9 130.6 960.4 315.7 270.1 1688.5 223.8 293.5 323.8 998.1 542.0 560.8 781.7 599.5 622.4 544.4 390.7 561.8 445.4 407.4 359.4 525.4 548.4 299.0 472.8 612.4 683.8 361.8 668.9 924.1 241.4 249.9 1082.7 854.6 1107.9 1435.2 659.0 1118.6 368.0 721.6 533.5 472.2 491.0 665.5 503.3 608.1 756.0 314.4 464.7 904.5 972.6 1337.3 861.9 1071.7 1438.9 584.4 555.0 620.7 863.9 1053.2 667.7 530.1 401.6 525.0 620.2 502.7 590.4 695.7 580.2 348.0 340.7 308.2 730.9 739.7 1273.2 947.0 528.0 712.7 391.3 1049.3 1044.5 1188.8 742.1 920.0 776.3 1470.4 909.2 839.0 1067.0 1131.6 837.1 811.9 962.2 943.5 822.7 1179.7 1086.3 1456.6 940.1 960.8 981.5 1172.2 932.5 968.9 980.1 955.6 972.5 952.6 960.4 998.1 311.8 153.8 199.7 0.0 88.6 0.0 0.0 0.0 0.0 0.0 461.7 421.8 0.0 0.0 121.9 886.5 0.0 404.9 188.8 0.0 1729.5 467.4 0.0 468.6 315.6 125.1 0.0 0.0 0.0 692.9 335.8 139.4 0.0 484.2 122.4 311.8 0.0 0.0 676.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 201.6 0.0 0.0 278.1 0.0 0.0 0.0 0.0 509.6 0.0 0.0 50.1 0.0 0.0 2485.3 183.6 0.0 0.0 0.0 156.7 0.0 0.0 0.0 0.0 274.9 97.8 146.6 0.0 0.0 ATP5MF "ATP5J2, ATP5JL" ENSG00000241468 "ATP synthase membrane subunit f" P56134 7 99448475-99466186 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 777.4;Distal tubular cells: 1430.2;Exocrine glandular cells: 578.8;Extravillous trophoblasts: 636.3;Hofbauer cells: 787.4;Pancreatic endocrine cells: 589.5;Proximal tubular cells: 1616.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067267, HPA070412" Approved Supported "Nuclear membrane,Mitochondria" NA NA 60000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Nuclear membrane" "HPA067267: AB_2685815, HPA070412: AB_2686266" "unprognostic (2.43e-2)" "unprognostic (1.42e-1)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (4.55e-3)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (6.19e-2)" "unprognostic (2.31e-3)" "unprognostic (2.58e-1)" "unprognostic (3.65e-2)" "unprognostic (6.88e-3)" "unprognostic (9.24e-2)" "unprognostic (4.90e-2)" "unprognostic (2.52e-1)" "unprognostic (5.78e-2)" 328.8 423.5 636.9 268.7 655.2 404.4 310.8 658.3 868.4 247.8 671.0 470.9 442.7 188.3 299.1 526.6 191.7 143.8 1184.8 658.1 663.7 559.3 561.2 241.8 293.1 657.5 648.0 179.1 271.6 509.6 332.1 235.7 647.0 315.5 367.9 320.7 317.8 205.9 1337.1 287.0 384.6 192.0 637.6 281.8 354.7 310.5 652.7 439.3 241.4 1439.0 301.2 303.1 303.5 641.3 1251.5 1130.6 905.3 1400.5 752.1 739.2 561.1 799.3 705.9 947.2 994.6 1226.2 1091.7 1161.7 822.7 548.5 1513.9 735.7 1064.0 981.3 1021.4 831.0 1333.6 800.1 1584.6 1555.4 530.7 1324.4 824.4 835.6 944.9 766.6 858.9 760.5 919.8 1009.4 1681.6 1213.0 1057.4 3128.1 1984.5 2396.1 1228.2 2594.9 1410.9 874.9 741.6 1985.9 1936.7 1376.1 845.3 925.9 1073.7 2519.4 773.1 1365.1 644.9 1687.5 703.0 706.0 1142.1 1197.3 1181.5 685.7 1795.6 2432.4 829.7 1325.8 1131.8 1020.3 904.1 1069.1 440.2 912.7 425.6 597.7 508.3 494.8 1122.9 512.2 445.1 468.3 428.0 555.2 731.2 890.5 754.9 1505.3 636.9 655.2 658.3 868.4 658.1 663.7 657.5 648.0 647.0 637.6 652.7 641.3 147.7 22.4 44.9 0.0 57.9 0.0 0.0 0.0 0.0 0.0 252.4 289.6 0.0 0.0 36.5 386.2 0.0 777.4 125.6 0.0 1430.2 460.9 0.0 302.6 225.3 82.0 0.0 0.0 0.0 578.8 636.3 110.5 0.0 278.3 64.3 188.1 0.0 0.0 787.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 190.2 0.0 0.0 339.1 0.0 0.0 0.0 0.0 589.5 0.0 0.0 18.6 0.0 0.0 1616.3 51.0 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 436.3 64.0 206.4 0.0 0.0 ATP5MG "ATP5JG, ATP5L" ENSG00000167283 "ATP synthase membrane subunit g" O75964 11 118401606-118431496 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1407.2;Distal tubular cells: 2907.4;Hofbauer cells: 1367.3;Proximal tubular cells: 2520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044629 Approved Supported Mitochondria NA NA 44000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA044629: AB_2679028" "unprognostic (1.70e-1)" "unprognostic (2.40e-2)" "unprognostic (2.21e-1)" "unprognostic (5.45e-2)" "unprognostic (1.61e-1)" "unprognostic (3.27e-2)" "unprognostic (3.90e-2)" "unprognostic (8.19e-2)" "unprognostic (5.13e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (7.41e-2)" "prognostic favorable (4.09e-5)" "unprognostic (6.26e-2)" "unprognostic (2.56e-1)" "unprognostic (1.50e-2)" "unprognostic (3.05e-2)" 119.8 137.2 154.2 103.3 158.5 165.6 132.5 158.5 184.3 81.1 168.3 153.6 146.4 79.3 143.3 116.9 96.5 68.1 329.8 157.2 160.8 205.1 154.5 77.9 150.0 155.5 153.1 112.0 110.9 140.7 49.5 83.7 154.0 83.5 164.3 100.8 133.9 92.2 340.7 55.3 118.2 95.2 153.6 86.0 112.3 46.9 155.5 204.1 87.5 373.6 183.1 105.3 41.5 154.7 163.1 87.9 209.3 183.1 167.6 198.0 200.1 149.0 175.9 138.4 146.6 259.9 259.9 314.3 352.7 167.5 206.2 190.4 204.4 214.8 155.3 247.6 138.0 472.8 112.5 197.4 175.3 279.3 210.2 207.1 203.4 169.0 162.9 164.1 189.8 216.6 227.4 253.1 199.5 305.8 365.2 497.3 130.1 427.9 224.0 247.0 174.9 422.9 371.1 260.3 184.3 161.9 232.3 361.1 161.9 221.6 303.0 307.7 172.8 123.0 144.7 109.2 190.9 112.8 184.8 402.1 93.8 353.0 154.7 325.4 437.2 299.0 241.8 360.8 339.7 462.7 398.8 321.5 481.2 378.5 472.9 379.7 214.8 357.2 333.3 534.3 464.5 1112.1 154.2 158.5 158.5 184.3 157.2 160.8 155.5 153.1 154.0 153.6 155.5 154.7 324.3 362.2 364.1 0.0 211.2 0.0 0.0 0.0 0.0 0.0 893.9 1061.2 0.0 0.0 166.5 610.6 0.0 1407.2 378.3 0.0 2907.4 748.6 0.0 449.8 327.9 188.9 0.0 0.0 0.0 986.0 935.6 204.7 0.0 404.6 258.6 368.2 0.0 0.0 1367.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 427.7 0.0 0.0 678.1 0.0 0.0 0.0 0.0 922.2 0.0 0.0 94.9 0.0 0.0 2520.3 188.0 0.0 0.0 0.0 217.5 0.0 0.0 0.0 0.0 1001.4 224.2 370.0 0.0 0.0 ATP5MPL "6.8PL, C14orf2, MLQ, MP68" ENSG00000156411 "ATP synthase membrane subunit 6.8PL" P56378 14 103912288-103928269 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1602.3;Extravillous trophoblasts: 671.4;Hofbauer cells: 920.9;Proximal tubular cells: 1883.7;Syncytiotrophoblasts: 710.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058978, HPA060520" Approved Supported "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Nucleoli fibrillar center" "HPA058978: AB_2683867, HPA060520: AB_2684302" "unprognostic (1.37e-1)" "unprognostic (1.42e-3)" "unprognostic (1.55e-1)" "unprognostic (2.30e-1)" "unprognostic (2.11e-1)" "unprognostic (1.20e-2)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "prognostic favorable (6.80e-4)" "unprognostic (1.34e-2)" "unprognostic (5.48e-2)" "unprognostic (1.34e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (1.57e-1)" "unprognostic (4.14e-2)" 107.8 166.9 304.6 75.7 318.3 177.4 127.5 305.8 446.6 94.9 306.0 165.2 165.1 80.5 139.6 159.4 87.0 48.8 548.2 321.9 313.4 205.2 181.9 79.9 94.4 301.2 297.7 98.3 113.8 257.3 159.9 77.1 302.4 108.5 167.5 169.9 100.9 87.8 489.6 106.1 128.9 78.9 303.1 108.7 135.6 83.4 305.5 135.0 111.5 471.6 122.5 103.0 101.1 304.1 244.6 278.5 233.6 222.8 275.0 284.2 228.5 185.2 211.7 228.6 199.5 240.6 167.4 254.4 187.9 191.2 183.4 201.1 306.4 225.3 310.0 207.9 306.8 280.4 227.5 380.4 180.4 346.2 188.4 298.6 301.5 155.7 164.2 260.8 264.4 330.6 176.7 264.7 253.7 730.8 333.1 493.9 182.1 560.5 523.7 211.5 202.7 231.2 358.4 345.0 201.2 238.4 155.9 289.0 371.4 256.2 355.3 401.7 142.7 87.9 137.9 242.0 153.2 199.3 372.5 360.2 207.8 195.7 152.3 405.1 512.8 336.0 204.9 409.1 232.9 309.5 261.1 234.1 367.0 261.9 295.5 260.0 517.5 206.2 401.4 355.4 282.2 656.9 304.6 318.3 305.8 446.6 321.9 313.4 301.2 297.7 302.4 303.1 305.5 304.1 88.0 221.2 225.1 0.0 47.9 0.0 0.0 0.0 0.0 0.0 369.7 334.4 0.0 0.0 92.2 413.8 0.0 609.1 63.1 0.0 1602.3 504.6 0.0 341.3 245.9 104.1 0.0 0.0 0.0 572.6 671.4 113.8 0.0 297.7 93.4 207.9 0.0 0.0 920.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 210.3 0.0 0.0 335.5 0.0 0.0 0.0 0.0 570.5 0.0 0.0 0.0 0.0 0.0 1883.7 146.5 0.0 0.0 0.0 104.8 0.0 0.0 0.0 0.0 710.1 70.2 228.6 0.0 0.0 ATP5PD "ATP5H, ATP5JD, ATPQ" ENSG00000167863 "ATP synthase peripheral stalk subunit d" O75947 17 75038863-75046985 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1142.6;Hofbauer cells: 465.0;Proximal tubular cells: 1059.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042777, HPA048459" Enhanced Supported Mitochondria NA NA 60000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042777: AB_2678160, HPA048459: AB_2680402" "unprognostic (1.37e-1)" "unprognostic (4.41e-2)" "unprognostic (1.70e-3)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "unprognostic (4.81e-2)" "unprognostic (7.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (2.72e-1)" "unprognostic (8.72e-2)" "unprognostic (2.56e-2)" "unprognostic (1.42e-1)" "unprognostic (3.26e-1)" "unprognostic (1.73e-1)" "unprognostic (4.29e-2)" 253.8 271.0 253.5 156.0 260.5 187.2 228.8 270.5 385.7 190.7 282.9 337.1 295.1 170.7 279.9 355.9 173.5 140.1 985.5 261.9 271.1 465.2 454.2 174.0 166.0 264.8 256.9 147.5 222.2 427.1 203.9 174.1 260.8 177.9 323.6 256.0 240.8 200.5 1102.8 264.7 257.4 211.3 260.2 155.0 307.4 93.8 262.3 175.2 263.7 1025.5 221.2 230.3 221.5 261.7 522.8 445.4 335.6 439.8 532.6 647.4 449.1 437.2 571.3 478.5 452.2 351.8 397.1 349.8 282.5 550.2 450.2 462.2 409.0 571.6 637.5 171.6 346.0 359.1 340.2 703.1 524.2 463.5 225.8 555.3 444.8 390.7 552.7 380.9 646.8 268.5 380.1 462.6 595.1 503.3 461.8 515.6 257.1 1185.3 626.9 322.3 970.4 652.3 1007.3 499.7 335.8 368.5 515.5 811.0 730.7 496.9 805.1 463.2 337.4 591.1 413.2 520.0 520.4 369.0 315.5 360.8 530.2 455.4 390.3 410.8 440.7 481.0 274.8 540.9 320.8 364.5 467.5 341.7 509.7 292.8 416.1 388.9 253.0 301.6 458.0 453.6 492.8 495.9 253.5 260.5 270.5 385.7 261.9 271.1 264.8 256.9 260.8 260.2 262.3 261.7 173.8 173.1 156.4 0.0 35.0 0.0 0.0 0.0 0.0 0.0 159.6 234.2 0.0 0.0 102.8 259.3 0.0 384.3 74.0 0.0 1142.6 313.6 0.0 188.2 153.6 70.4 0.0 0.0 0.0 379.5 328.4 82.7 0.0 207.6 88.3 84.6 0.0 0.0 465.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.1 0.0 0.0 208.8 0.0 0.0 0.0 0.0 284.3 0.0 0.0 13.8 0.0 0.0 1059.2 101.3 0.0 0.0 0.0 88.3 0.0 0.0 0.0 0.0 336.3 54.4 155.9 0.0 0.0 ATP5PF "ATP5, ATP5A, ATP5J, ATPM, CF6" ENSG00000154723 "ATP synthase peripheral stalk subunit F6" P18859 21 25716503-25735673 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1595.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 2375.2;Proximal tubular cells: 1906.2;Syncytiotrophoblasts: 708.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031069 Supported Supported Mitochondria NA NA 820000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA031069: AB_10603676" "unprognostic (3.52e-2)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (7.87e-2)" "unprognostic (1.43e-1)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (4.87e-2)" "unprognostic (1.77e-1)" "unprognostic (8.83e-2)" "prognostic favorable (2.37e-5)" "unprognostic (1.93e-1)" "unprognostic (9.20e-2)" "unprognostic (1.56e-1)" "unprognostic (2.15e-2)" 274.6 276.3 291.2 136.4 295.4 175.1 205.5 302.5 424.4 156.3 316.1 333.5 276.4 128.8 368.1 258.1 129.9 129.7 1052.1 295.2 306.2 489.5 756.3 110.8 166.4 299.3 297.8 127.2 188.2 458.8 140.4 171.5 295.7 160.1 314.4 249.5 214.6 228.5 1161.7 113.6 250.6 189.8 298.7 111.2 226.9 131.5 299.4 217.5 166.0 1595.8 210.9 194.9 138.4 299.6 355.9 260.0 314.5 351.4 344.8 313.5 389.4 305.8 373.0 305.8 300.8 607.6 274.4 439.3 194.2 312.9 467.8 191.5 441.3 379.2 339.2 373.1 441.1 910.6 520.6 618.4 386.8 673.2 284.5 303.1 471.2 284.0 258.6 399.9 363.0 412.2 582.2 522.9 458.2 416.3 468.6 683.2 562.3 824.0 460.7 358.0 606.5 840.0 669.8 504.6 360.2 394.1 516.5 521.7 493.0 449.4 376.5 590.5 260.6 219.6 266.6 209.3 265.9 501.7 954.7 568.2 341.5 707.8 283.1 444.8 447.0 443.7 293.3 487.1 316.1 475.1 385.5 368.6 531.9 399.7 377.4 370.7 292.3 389.9 505.7 504.0 520.3 661.3 291.2 295.4 302.5 424.4 295.2 306.2 299.3 297.8 295.7 298.7 299.4 299.6 532.1 169.9 179.3 0.0 56.0 0.0 0.0 0.0 0.0 0.0 346.3 468.4 0.0 0.0 105.9 419.3 0.0 652.7 116.4 0.0 2375.2 447.0 0.0 299.2 257.6 150.6 0.0 0.0 0.0 472.5 522.8 135.6 0.0 308.5 109.7 341.2 0.0 0.0 522.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 154.2 0.0 0.0 226.4 0.0 0.0 0.0 0.0 427.1 0.0 0.0 21.4 0.0 0.0 1906.2 142.1 0.0 0.0 0.0 161.4 0.0 0.0 0.0 0.0 708.2 79.2 387.8 0.0 0.0 ATP5PO "ATP5O, ATPO, OSCP" ENSG00000241837 "ATP synthase peripheral stalk subunit OSCP" P48047 21 33903453-33915814 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1601.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 610.3;Distal tubular cells: 1794.2;Extravillous trophoblasts: 623.2;Hofbauer cells: 627.0;Proximal tubular cells: 1236.8;Syncytiotrophoblasts: 542.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016209, HPA041394" Enhanced Approved Mitochondria NA NA 150000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB016209: AB_631361, HPA041394: AB_2677450" "unprognostic (2.08e-1)" "unprognostic (4.77e-3)" "unprognostic (3.30e-1)" "unprognostic (6.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (2.34e-1)" "unprognostic (8.47e-2)" "unprognostic (1.42e-1)" "unprognostic (3.27e-1)" "unprognostic (1.81e-1)" "prognostic favorable (9.34e-4)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (3.26e-2)" "unprognostic (7.89e-3)" 213.0 181.0 282.7 147.9 289.4 310.6 280.4 306.0 417.7 204.8 325.2 351.9 357.2 169.2 251.1 288.3 216.7 157.9 1114.5 291.2 317.4 458.0 401.8 148.9 243.3 298.2 290.8 273.1 196.7 432.9 108.0 192.2 296.5 158.0 391.9 219.4 236.3 202.0 1063.7 188.4 293.8 217.4 290.9 143.4 304.2 150.3 291.4 281.7 224.4 1601.7 292.9 242.3 161.6 292.4 398.4 187.3 491.1 486.6 340.0 435.1 554.6 218.5 394.4 371.4 361.9 553.5 372.7 531.5 187.2 345.1 355.2 217.5 549.0 764.7 440.6 400.0 544.0 790.3 260.4 513.5 389.7 603.7 260.9 445.8 467.9 358.4 581.9 407.0 522.8 421.2 656.3 665.9 488.5 402.5 461.6 593.0 561.3 992.2 540.1 471.6 490.1 1007.5 1032.8 337.0 404.4 232.1 380.2 559.7 525.7 425.6 562.9 660.5 291.0 236.8 280.6 423.0 252.6 429.1 524.2 559.7 438.2 1046.2 349.3 329.7 561.5 407.8 335.9 596.2 400.9 575.4 439.5 404.8 753.0 487.3 540.9 459.4 136.2 412.6 539.8 445.4 585.3 1077.9 282.7 289.4 306.0 417.7 291.2 317.4 298.2 290.8 296.5 290.9 291.4 292.4 195.8 243.6 191.1 0.0 82.1 0.0 0.0 0.0 0.0 0.0 282.6 476.1 0.0 0.0 121.3 222.5 0.0 610.3 81.3 0.0 1794.2 394.5 0.0 133.0 140.9 87.3 0.0 0.0 0.0 420.2 623.2 109.7 0.0 114.8 114.8 198.9 0.0 0.0 627.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 131.2 0.0 0.0 218.1 0.0 0.0 0.0 0.0 331.9 0.0 0.0 17.8 0.0 0.0 1236.8 102.0 0.0 0.0 0.0 119.0 0.0 0.0 0.0 0.0 542.1 67.4 208.9 0.0 0.0 ATP6V0D1 "ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD" ENSG00000159720 "ATPase H+ transporting V0 subunit d1" P61421 16 67438014-67481181 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 380.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016938 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA016938: AB_1845191" "unprognostic (1.12e-2)" "unprognostic (1.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.79e-3)" "unprognostic (8.57e-2)" "unprognostic (2.93e-1)" "unprognostic (1.20e-2)" "unprognostic (8.30e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.20e-5)" "unprognostic (5.72e-3)" "prognostic favorable (1.76e-8)" "unprognostic (2.72e-1)" "unprognostic (6.42e-2)" "unprognostic (2.63e-2)" "unprognostic (4.33e-3)" 51.3 112.9 103.1 66.9 107.1 82.3 50.3 84.1 118.4 65.2 82.4 89.8 69.0 69.2 56.6 88.6 57.8 55.9 71.5 119.9 145.1 86.2 73.0 78.7 66.9 112.6 107.4 35.1 59.2 116.3 107.7 55.8 136.0 60.5 72.7 41.4 62.8 55.0 127.6 85.9 79.9 79.6 82.6 96.1 69.4 69.5 99.4 64.7 75.1 84.7 64.0 66.8 62.2 98.5 78.9 111.6 67.3 87.5 167.2 91.2 64.3 92.7 149.1 187.0 224.3 116.5 82.6 33.0 74.2 134.7 125.3 91.9 99.0 117.7 108.8 40.3 90.5 60.5 58.4 97.6 159.4 60.5 243.3 139.8 115.1 187.4 44.5 68.2 117.9 38.0 69.7 41.9 151.9 193.7 45.7 134.9 65.2 70.6 77.9 80.2 78.5 92.1 113.3 129.3 130.4 60.4 244.0 65.8 103.1 52.3 104.8 91.1 114.4 93.4 38.6 113.9 49.8 69.5 106.8 94.9 130.1 63.8 56.3 312.7 732.5 542.4 130.1 511.7 89.9 189.4 96.3 120.3 469.2 174.5 73.1 91.3 936.5 155.5 485.5 168.4 128.0 742.7 103.1 107.1 84.1 118.4 119.9 145.1 112.6 107.4 136.0 82.6 99.4 98.5 46.0 16.0 47.2 11.1 80.1 73.8 61.5 138.2 45.5 73.3 65.7 50.5 38.8 54.3 78.0 68.0 73.0 112.1 74.7 258.8 181.9 127.7 109.6 93.3 46.4 42.6 121.9 68.8 22.7 111.0 73.1 61.5 68.3 74.5 50.1 44.2 42.5 50.2 380.4 82.4 25.7 160.2 154.6 149.4 186.7 50.1 58.7 183.1 124.5 7.5 260.9 70.6 77.2 13.6 23.1 102.0 179.5 53.0 57.0 38.8 203.1 173.6 92.7 52.9 118.3 26.6 53.2 125.7 64.0 55.0 87.5 283.6 54.7 91.3 101.6 63.2 ATP6V1C1 "ATP6C, ATP6D, VATC, Vma5" ENSG00000155097 "ATPase H+ transporting V1 subunit C1" P21283 8 103021063-103073051 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 162.7;Late spermatids: 166.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023943, HPA057297" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA023943: AB_1845197, HPA057297: AB_2683402" "unprognostic (5.73e-3)" "unprognostic (3.30e-1)" "unprognostic (1.09e-2)" "unprognostic (1.93e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.29e-2)" "unprognostic (3.87e-1)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (3.98e-2)" "unprognostic (1.23e-1)" "unprognostic (3.85e-1)" "unprognostic (3.88e-1)" "unprognostic (2.83e-1)" 23.8 32.2 31.6 23.8 36.8 9.7 21.6 18.7 38.2 17.8 20.7 15.4 16.1 19.0 14.2 15.6 16.8 19.8 30.1 39.4 28.9 51.7 27.5 18.6 26.2 25.4 24.5 17.7 18.8 39.0 22.2 30.2 31.5 18.3 18.8 36.7 15.3 16.1 17.2 11.9 17.8 20.6 20.2 19.9 17.4 20.9 25.5 21.9 37.8 24.3 24.5 25.2 14.0 26.3 68.4 38.6 20.2 15.6 54.6 39.3 27.7 49.0 49.7 60.6 68.9 30.4 76.7 41.2 58.2 40.8 97.5 29.6 42.4 41.0 87.8 30.3 26.4 39.2 28.0 35.8 59.5 20.8 52.5 28.8 55.4 77.4 36.2 35.6 43.9 28.7 54.6 37.3 71.4 32.1 46.2 16.7 19.1 67.9 37.6 24.6 36.0 36.4 70.3 48.8 28.5 22.6 26.9 26.9 102.0 40.5 58.9 27.8 44.4 33.2 36.1 74.3 35.0 45.1 17.7 42.1 60.2 47.2 33.2 16.8 30.5 38.1 15.1 44.9 17.2 18.7 12.7 15.1 29.0 18.7 14.4 16.0 50.2 18.7 42.7 15.8 23.1 21.1 31.6 36.8 18.7 38.2 39.4 28.9 25.4 24.5 31.5 20.2 25.5 26.3 31.3 32.1 26.4 38.2 22.9 34.9 33.1 31.2 21.1 32.3 21.9 20.6 43.3 15.7 26.5 31.3 16.7 35.4 15.5 14.7 64.6 36.9 162.7 18.3 19.5 25.5 15.6 33.6 64.9 31.5 35.6 28.4 12.2 16.4 24.1 14.0 17.5 19.0 101.8 37.0 56.6 12.4 46.8 47.6 99.6 166.9 24.2 62.8 19.6 36.5 34.3 34.5 14.4 39.2 44.7 30.4 18.2 18.4 25.1 34.7 19.2 139.1 41.2 25.3 19.7 20.7 45.5 11.1 23.4 19.5 32.8 74.8 18.5 17.4 13.5 27.4 ATP6V1D "ATP6M, VATD, VMA8" ENSG00000100554 "ATPase H+ transporting V1 subunit D" Q9Y5K8 14 67294371-67360265 "Metabolic proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 365.9;Proximal tubular cells: 365.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031515, HPA057316" Enhanced Approved Nucleoplasm Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA031515: AB_10600785, HPA057316: AB_2683409" "unprognostic (1.10e-1)" "unprognostic (7.35e-2)" "unprognostic (1.59e-1)" "unprognostic (7.10e-3)" "unprognostic (1.52e-1)" "unprognostic (7.64e-2)" "unprognostic (7.78e-3)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.05e-2)" "unprognostic (1.13e-2)" "unprognostic (3.08e-2)" "prognostic favorable (7.60e-13)" "unprognostic (2.78e-1)" "unprognostic (3.18e-2)" "unprognostic (1.41e-2)" "unprognostic (1.44e-2)" 43.4 116.2 98.0 32.2 103.2 28.8 43.8 91.8 119.7 40.3 101.8 52.9 40.4 34.3 72.5 96.7 48.1 38.7 136.6 107.2 103.5 129.8 51.7 37.5 33.3 96.1 98.4 26.1 36.2 88.8 65.8 43.4 106.7 55.7 57.5 78.0 45.1 49.8 78.5 40.4 41.7 46.4 95.1 24.3 43.8 42.5 99.7 52.4 89.5 108.5 46.3 54.5 54.1 99.6 242.5 64.7 96.2 62.4 80.2 82.8 73.5 199.1 109.4 145.8 109.1 76.2 85.2 24.8 73.9 155.1 105.3 89.2 72.6 117.9 195.7 82.5 50.8 23.4 74.5 51.0 144.0 24.9 64.8 65.1 77.7 105.4 73.1 131.4 97.6 58.6 50.2 55.3 206.6 78.5 66.5 46.2 60.7 104.6 83.3 48.8 84.2 32.8 171.2 104.3 120.2 49.8 122.9 65.4 145.6 96.2 98.3 53.4 123.8 162.4 121.6 77.6 120.1 55.8 46.1 33.4 150.2 44.1 96.1 106.7 77.5 92.8 48.5 78.8 40.8 39.9 53.2 52.7 83.4 42.0 41.6 41.7 94.0 48.9 83.5 73.9 78.8 65.0 98.0 103.2 91.8 119.7 107.2 103.5 96.1 98.4 106.7 95.1 99.7 99.6 31.3 54.5 63.0 13.4 27.6 96.2 66.6 112.3 26.2 60.0 44.8 41.8 160.8 55.8 85.0 82.8 54.2 92.3 51.4 91.6 365.9 125.9 190.3 120.8 44.1 40.7 54.4 78.1 22.7 48.9 85.5 51.5 42.3 71.8 41.2 39.8 27.5 45.8 132.0 87.5 21.0 49.4 175.0 44.6 61.0 97.9 32.9 62.2 80.0 6.5 58.5 89.4 47.4 9.5 22.1 121.5 78.7 50.8 21.3 65.9 80.9 365.5 184.1 94.2 13.1 44.5 64.1 100.1 61.5 78.4 138.4 205.9 40.8 71.6 40.6 113.8 ATP6V1E1 "ATP6E, ATP6E2, ATP6V1E, P31, Vma4" ENSG00000131100 "ATPase H+ transporting V1 subunit E1" P36543 22 17592136-17628749 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 461.8;Proximal tubular cells: 411.3;Syncytiotrophoblasts: 479.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009528, CAB018699, HPA029196" Enhanced Approved Nucleoplasm NA NA 34000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB009528: AB_2062678, CAB018699: AB_781534, HPA029196: AB_2672944" "unprognostic (1.53e-3)" "unprognostic (5.78e-3)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.17e-1)" "unprognostic (2.09e-1)" "unprognostic (3.37e-2)" "unprognostic (7.72e-3)" "prognostic favorable (4.18e-4)" "prognostic favorable (7.66e-8)" "unprognostic (3.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (2.75e-1)" 119.5 165.0 209.8 68.3 220.9 90.4 109.5 214.3 287.3 101.7 200.4 128.9 56.6 112.2 135.8 117.2 96.0 84.7 224.9 231.8 226.9 230.5 85.6 110.3 88.6 220.3 202.3 81.9 59.5 239.9 117.1 113.8 230.8 95.0 99.7 128.4 83.7 126.4 232.8 120.3 83.1 121.0 215.9 99.0 101.8 67.3 218.1 108.2 100.8 178.6 109.5 114.5 97.6 245.6 121.8 108.6 96.4 94.3 314.4 169.6 106.0 159.3 212.0 198.7 228.0 137.3 97.5 76.1 132.8 215.0 251.8 187.9 152.8 140.2 174.9 145.9 173.3 137.1 97.5 182.7 459.9 159.8 226.5 212.9 267.7 192.4 138.7 220.9 170.2 95.0 174.8 150.3 341.9 127.4 136.5 114.5 71.0 269.6 152.6 80.3 140.7 45.7 331.6 189.0 70.3 122.7 146.0 101.0 358.9 187.0 98.6 180.4 146.3 137.5 72.6 174.0 119.2 145.7 275.5 96.3 221.2 76.7 189.3 178.1 106.3 184.7 64.0 100.9 63.0 78.7 64.7 61.5 83.6 59.8 60.8 63.7 137.6 76.0 120.5 81.2 97.7 112.8 209.8 220.9 214.3 287.3 231.8 226.9 220.3 202.3 230.8 215.9 218.1 245.6 66.5 76.9 83.4 13.4 47.1 41.9 77.6 121.8 19.9 54.6 33.9 34.8 126.8 74.4 83.9 138.0 27.1 235.1 63.8 105.2 461.8 143.8 7.6 74.3 56.9 69.3 41.9 49.4 24.9 119.7 143.9 60.8 40.8 79.2 90.5 41.6 72.5 46.8 186.8 53.8 24.4 54.0 116.0 75.1 52.1 17.9 94.1 91.9 80.0 15.0 144.1 94.1 85.5 13.0 31.9 154.7 104.7 97.8 38.3 60.1 65.4 411.3 78.8 50.4 59.2 39.0 74.5 71.7 74.7 34.3 51.6 479.1 54.6 57.6 40.1 93.1 ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 8300 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: AB_667834, HPA023421: AB_1845202" "unprognostic (1.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (2.16e-2)" "unprognostic (2.38e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (2.01e-1)" "unprognostic (1.95e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "prognostic favorable (1.46e-7)" "unprognostic (1.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" 24.1 44.6 42.5 15.9 46.7 25.6 26.0 27.5 58.8 23.9 30.2 31.6 12.9 25.4 32.9 34.1 22.6 20.7 31.2 57.4 38.0 60.5 19.1 24.2 21.4 30.5 30.2 24.1 17.4 47.7 42.4 23.9 32.7 30.2 20.4 37.4 28.7 27.4 37.8 35.2 19.1 24.1 29.4 20.3 31.8 18.5 31.0 26.6 52.4 27.3 22.0 28.5 26.4 37.9 42.8 35.6 29.8 31.8 50.9 32.9 23.4 40.5 44.5 54.8 56.7 33.5 54.1 27.2 38.7 40.9 69.7 67.8 52.6 58.9 56.1 39.9 35.8 28.8 34.3 40.9 69.1 19.6 31.8 46.5 82.3 37.2 66.4 52.5 37.8 28.9 39.4 14.0 81.6 36.0 30.6 32.5 27.4 37.0 17.4 28.2 10.6 18.6 88.4 67.4 23.5 34.9 28.7 54.6 79.5 34.4 64.0 16.3 43.2 24.4 19.7 54.6 25.5 25.9 30.4 32.3 57.8 27.4 27.5 25.7 14.8 36.2 13.2 16.6 14.9 13.6 14.3 15.4 20.2 12.0 14.4 16.0 14.5 22.6 23.4 15.9 20.7 11.8 42.5 46.7 27.5 58.8 57.4 38.0 30.5 30.2 32.7 29.4 31.0 37.9 18.2 38.5 27.4 84.2 39.0 29.6 40.1 55.5 42.1 72.8 27.8 21.0 28.9 38.6 50.3 58.8 112.6 76.0 35.9 39.0 105.7 49.1 8.3 94.1 27.7 25.4 35.3 27.0 154.7 31.1 43.6 23.6 26.0 145.7 15.8 22.0 28.9 21.9 64.7 62.2 105.8 17.4 75.3 43.0 103.6 8.5 43.2 52.9 30.2 42.2 35.1 48.4 37.0 58.3 57.7 44.1 30.1 48.2 20.9 32.5 31.4 64.9 39.6 76.4 19.7 16.8 24.6 28.5 52.9 37.6 31.4 100.0 38.1 36.4 21.8 41.4 ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 263.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 284.7;Distal tubular cells: 172.1;Early spermatids: 261.4;Late spermatids: 373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028382: AB_2672574, HPA044950: AB_2679151" "unprognostic (1.34e-1)" "unprognostic (2.97e-3)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (5.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "prognostic favorable (5.33e-7)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" 66.0 89.9 87.5 23.3 94.4 27.4 30.2 97.1 115.2 30.0 102.8 44.9 35.3 22.5 29.4 30.1 27.3 25.8 221.0 82.9 107.7 97.1 95.3 21.9 27.9 85.8 85.6 28.8 41.2 121.5 43.8 32.3 85.3 32.2 48.1 63.9 48.4 29.0 221.0 20.1 35.2 32.3 80.7 21.6 42.1 41.5 90.6 37.8 37.1 263.4 28.5 26.4 20.2 82.2 57.8 46.1 61.1 54.8 65.1 52.3 51.0 42.2 52.6 62.0 49.7 37.2 24.5 34.1 55.2 53.6 54.9 43.6 97.3 54.7 83.1 75.0 76.7 60.2 54.5 65.0 52.4 60.2 3.4 51.4 64.3 66.5 57.7 49.2 39.3 62.8 28.2 65.4 48.0 52.3 89.3 33.3 96.3 49.8 68.8 38.1 16.5 74.3 71.4 45.2 71.8 53.8 71.4 74.9 114.6 70.0 69.3 83.8 34.4 21.1 52.1 43.1 58.5 80.6 78.9 23.2 34.7 23.0 40.6 0.0 1.6 4.1 2.1 2.8 2.7 1.8 2.2 2.5 1.6 1.2 3.1 1.4 1.3 5.6 1.2 1.2 4.5 1.2 87.5 94.4 97.1 115.2 82.9 107.7 85.8 85.6 85.3 80.7 90.6 82.2 12.6 3.2 18.6 31.0 22.3 9.4 21.2 9.7 27.3 34.0 27.8 19.4 284.7 31.5 13.1 31.3 27.1 64.0 14.5 26.7 172.1 22.1 261.4 15.6 15.4 13.2 19.2 31.3 37.1 20.1 30.0 28.5 29.0 15.9 15.9 40.6 10.4 39.8 39.2 47.1 48.5 38.1 16.2 21.6 12.9 373.7 19.0 16.1 24.9 15.9 14.6 39.2 15.5 28.1 33.7 11.3 18.0 26.7 36.3 15.2 30.2 119.1 10.2 29.2 26.3 25.1 28.9 45.2 40.4 34.3 13.5 46.9 19.2 55.1 42.2 21.9 AURKAIP1 "AIP, AKIP, FLJ20608" ENSG00000175756 "Aurora kinase A interacting protein 1" Q9NWT8 1 1373730-1375495 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1314.3;Late spermatids: 3668.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031821 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA031821: AB_10601458" "unprognostic (9.54e-2)" "unprognostic (1.86e-2)" "unprognostic (2.77e-1)" "unprognostic (4.77e-2)" "unprognostic (2.68e-1)" "unprognostic (2.98e-2)" "unprognostic (3.31e-1)" "unprognostic (9.52e-2)" "unprognostic (2.76e-1)" "unprognostic (9.91e-2)" "unprognostic (3.39e-2)" "unprognostic (3.34e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.18e-2)" "unprognostic (1.84e-1)" 98.0 129.1 116.2 43.4 117.6 51.5 90.0 125.2 142.4 64.9 130.2 110.5 71.7 70.0 23.5 118.0 64.1 26.1 260.8 113.4 116.3 151.8 215.8 67.2 41.4 125.6 116.8 58.2 120.1 73.4 92.3 35.8 116.1 85.9 27.5 23.6 88.2 38.7 281.3 91.0 85.6 22.4 116.9 85.8 121.4 300.6 128.4 37.9 83.1 171.3 27.2 87.2 72.9 118.4 197.8 116.9 62.9 113.6 54.6 68.2 115.7 116.8 76.8 180.7 127.6 206.3 177.5 103.2 169.3 79.6 90.7 142.4 86.5 154.6 51.9 124.7 245.8 83.6 156.1 194.0 106.7 109.0 109.0 90.4 68.6 127.1 51.3 52.8 99.2 96.3 167.2 138.5 106.6 150.3 134.7 386.9 119.1 123.2 329.1 154.8 77.5 222.7 145.9 51.6 200.7 150.6 83.7 288.4 295.1 38.1 125.0 250.7 75.5 111.3 144.4 134.1 175.7 179.1 177.0 223.4 155.3 159.2 77.1 279.1 231.8 266.6 171.6 200.3 162.7 190.6 178.4 181.7 207.4 202.7 166.6 161.1 291.7 142.4 177.7 294.0 230.1 225.6 116.2 117.6 125.2 142.4 113.4 116.3 125.6 116.8 116.1 116.9 128.4 118.4 118.9 48.1 73.5 18.9 137.4 162.3 166.4 271.4 87.0 109.8 228.1 240.2 231.3 180.1 149.6 165.5 64.6 384.1 134.7 642.0 677.0 310.2 1314.3 145.6 119.3 127.6 203.9 125.2 11.2 418.4 458.6 121.0 178.4 141.8 87.5 144.6 121.1 390.5 294.6 104.3 12.8 415.1 238.0 154.8 175.5 3668.5 136.1 149.7 217.1 5.6 208.1 299.8 166.9 13.0 17.9 425.2 484.3 118.5 240.5 272.5 607.4 780.2 142.2 124.5 157.8 104.4 152.4 572.4 149.2 190.4 197.6 438.1 116.3 181.0 414.3 270.1 B3GLCT "B3GALTL, B3Glc-T, B3GTL" ENSG00000187676 "Beta 3-glucosyltransferase" Q6Y288 13 31199975-31332276 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 59.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (3.31e-2)" "unprognostic (2.53e-1)" "unprognostic (4.71e-2)" "unprognostic (6.17e-3)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-1)" "unprognostic (2.91e-1)" "unprognostic (3.28e-3)" "unprognostic (6.74e-2)" "unprognostic (5.51e-3)" "unprognostic (2.26e-1)" "unprognostic (5.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.51e-1)" 3.7 2.0 8.6 3.1 11.4 3.9 4.6 6.2 7.8 3.5 12.8 3.1 2.8 12.9 3.9 3.0 6.0 3.5 18.2 8.2 6.9 6.6 3.4 3.7 3.8 6.9 11.2 4.8 3.1 8.1 3.0 7.0 7.1 3.5 3.3 8.0 3.8 6.2 4.7 3.4 2.9 12.7 8.0 3.5 3.4 3.8 13.2 4.9 4.9 2.8 5.6 2.5 3.5 8.0 4.8 6.7 27.1 4.9 5.1 5.1 4.4 11.6 13.0 13.9 9.8 3.5 13.2 19.4 8.3 13.6 26.2 7.9 6.1 7.5 12.9 59.8 11.7 1.3 5.9 5.1 3.2 7.8 10.1 5.9 8.4 8.0 6.8 14.2 12.5 9.5 3.5 3.0 11.0 6.1 11.7 2.4 7.9 7.0 4.1 10.4 8.8 0.6 6.2 6.7 2.5 11.0 10.0 4.7 13.2 6.3 2.3 8.9 17.6 14.0 9.4 6.5 11.7 2.4 5.6 7.3 4.5 5.8 18.9 1.7 0.4 1.3 2.4 0.4 3.5 1.3 1.5 2.7 0.4 0.6 1.2 1.6 0.2 1.4 0.4 0.4 0.9 1.4 8.6 11.4 6.2 7.8 8.2 6.9 6.9 11.2 7.1 8.0 13.2 8.0 4.5 0.0 3.1 0.0 6.6 0.0 3.6 0.0 14.2 10.6 5.1 3.4 23.7 2.8 0.6 9.2 16.7 0.3 7.9 2.5 1.9 4.3 12.1 9.2 5.3 6.5 1.2 1.7 0.0 4.6 2.1 9.0 5.6 4.2 0.0 3.3 8.9 5.5 3.6 0.0 0.0 1.5 0.0 3.2 0.0 2.5 1.5 3.3 0.0 0.0 0.9 5.8 6.2 0.0 0.0 5.6 2.3 3.4 6.4 2.3 2.6 2.6 1.5 4.3 13.1 4.1 5.2 2.1 13.5 7.7 0.0 0.3 6.5 2.3 1.7 1.6 BAG1 ENSG00000107262 "BAG cochaperone 1" Q99933 9 33247820-33264720 "Cancer-related genes, Predicted intracellular proteins" Apoptosis Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1043.2;Late spermatids: 2944.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 437.5;NB-4: 417.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002486, HPA018121, HPA073236" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB002486: AB_563422, HPA018121: AB_1845255, HPA073236: " "unprognostic (4.49e-3)" "unprognostic (4.52e-2)" "unprognostic (2.33e-2)" "unprognostic (1.32e-3)" "unprognostic (5.46e-2)" "unprognostic (3.67e-3)" "unprognostic (2.10e-1)" "unprognostic (1.34e-2)" "unprognostic (4.62e-2)" "unprognostic (7.21e-2)" "unprognostic (4.24e-1)" "unprognostic (2.23e-1)" "prognostic favorable (2.22e-16)" "unprognostic (4.45e-2)" "unprognostic (4.03e-1)" "unprognostic (7.64e-3)" "unprognostic (1.07e-2)" 79.7 76.3 96.6 36.3 106.7 85.0 72.3 102.2 112.3 65.0 106.0 122.5 59.3 59.8 53.9 103.2 54.8 39.1 192.9 86.4 102.8 151.6 83.4 82.5 35.5 107.4 105.2 45.6 91.7 139.6 99.3 47.1 98.8 88.0 75.4 82.2 97.4 68.4 297.7 113.8 66.1 42.7 100.2 66.0 102.5 87.9 104.3 45.1 71.6 206.1 55.2 121.5 78.8 101.6 56.0 56.1 46.8 103.3 69.9 40.9 63.6 46.5 64.6 68.4 69.8 39.7 54.1 181.2 33.6 46.6 24.5 69.8 54.8 37.9 45.0 96.5 52.1 90.2 437.5 62.5 58.9 210.1 110.0 41.5 205.6 32.3 76.8 32.2 82.4 48.0 108.7 92.1 57.8 89.7 152.4 417.0 90.8 73.9 81.2 78.7 63.7 119.6 87.1 164.8 149.1 88.5 192.7 176.9 46.0 18.7 80.5 261.8 44.1 30.5 37.8 89.9 78.0 74.9 125.3 100.4 25.5 114.1 17.7 29.1 20.7 57.9 10.0 22.2 9.0 14.7 11.2 11.9 26.1 25.6 15.7 9.1 10.2 15.3 22.3 33.9 15.2 10.2 96.6 106.7 102.2 112.3 86.4 102.8 107.4 105.2 98.8 100.2 104.3 101.6 107.7 89.8 67.5 5.2 69.4 429.9 279.4 193.3 172.4 84.0 134.1 123.6 144.4 127.2 157.0 218.8 58.4 154.7 113.7 211.4 397.2 135.6 1043.2 109.3 72.2 86.6 198.1 259.1 5.9 189.0 59.9 79.4 104.5 193.3 41.9 36.7 66.8 72.8 104.9 38.7 7.1 287.8 170.9 86.4 162.7 2944.9 85.7 93.9 163.7 2.8 81.0 123.9 88.6 4.5 9.7 131.1 259.2 88.8 110.3 505.4 247.9 286.1 71.8 131.3 98.6 98.5 109.9 87.9 64.4 261.1 561.5 245.9 69.6 103.7 222.4 531.4 BBS2 BBS ENSG00000125124 "Bardet-Biedl syndrome 2" Q9BXC9 16 56466836-56520087 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 144.3;Oligodendrocytes: 97.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041315 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA041315: AB_10960892" "unprognostic (1.43e-1)" "unprognostic (3.13e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (7.58e-2)" "unprognostic (1.51e-2)" "unprognostic (4.22e-2)" "unprognostic (2.79e-2)" "unprognostic (2.11e-1)" "unprognostic (3.29e-2)" "unprognostic (3.76e-3)" "unprognostic (2.68e-1)" "prognostic favorable (2.83e-6)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" "unprognostic (2.95e-1)" "unprognostic (2.95e-2)" 20.3 78.3 90.1 9.3 102.5 6.0 29.5 93.2 117.7 31.1 80.7 23.6 13.5 25.9 47.1 23.2 32.7 21.6 32.8 87.5 89.4 41.7 13.2 20.2 18.4 94.4 90.4 40.7 15.7 53.7 38.1 16.1 96.2 26.9 16.9 86.5 20.0 27.0 41.5 36.4 17.7 24.0 89.4 21.0 17.2 28.6 91.5 18.3 28.1 50.8 16.2 21.1 29.7 107.9 22.3 19.7 29.6 29.9 47.1 56.9 17.4 10.7 40.9 23.1 29.8 11.0 18.0 22.1 17.6 24.3 19.0 25.3 11.7 36.4 36.0 4.9 26.3 10.4 19.4 28.1 30.7 12.1 11.4 35.4 26.7 18.3 16.8 49.0 50.0 16.7 4.7 2.7 28.9 15.2 16.8 14.1 7.9 14.9 32.7 12.9 8.3 25.7 36.2 18.1 20.7 15.5 51.9 20.2 27.8 23.7 17.2 14.3 43.3 18.3 11.6 8.3 5.7 10.4 8.7 17.1 31.6 10.5 13.7 9.9 9.6 24.5 15.6 13.6 15.8 11.4 18.7 20.6 11.8 12.4 24.4 23.2 2.7 7.4 22.4 3.4 16.4 14.0 90.1 102.5 93.2 117.7 87.5 89.4 94.4 90.4 96.2 89.4 91.5 107.9 11.5 0.0 24.3 144.3 9.6 11.2 15.6 19.1 23.9 21.5 10.7 11.3 24.4 5.7 18.7 11.0 25.0 14.3 6.6 8.7 7.9 7.1 21.1 22.4 10.7 12.3 6.7 4.6 41.0 5.8 7.3 18.6 7.7 16.9 10.1 27.0 12.1 6.9 11.2 20.2 39.6 10.3 24.4 11.3 6.3 19.7 18.0 8.9 10.6 26.2 9.0 26.6 7.2 71.4 97.8 6.0 10.4 20.7 4.1 4.7 11.5 20.0 56.1 34.6 19.7 16.7 12.0 18.4 20.7 13.1 14.1 7.5 10.5 59.2 11.1 10.0 BCAS3 FLJ20128 ENSG00000141376 "BCAS3 microtubule associated cell migration factor" Q9H6U6 17 60677453-61392838 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Astrocytes: 241.9;Excitatory neurons: 298.7;Inhibitory neurons: 299.2;Late spermatids: 282.3;Microglial cells: 244.5;Oligodendrocyte precursor cells: 285.0;Oligodendrocytes: 552.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 88.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052409, HPA057289" Approved Approved Nucleoli NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "HPA052409: AB_2681821, HPA057289: AB_2683399" "unprognostic (2.84e-2)" "prognostic favorable (2.04e-4)" "unprognostic (1.20e-1)" "unprognostic (3.52e-1)" "unprognostic (5.52e-1)" "unprognostic (3.60e-2)" "unprognostic (5.69e-2)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (2.47e-1)" "prognostic favorable (1.23e-5)" "unprognostic (2.55e-1)" "prognostic favorable (1.73e-5)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" 9.7 11.6 12.7 4.5 14.2 6.4 9.0 13.8 15.8 9.4 12.0 10.0 4.8 9.3 12.1 9.5 13.9 7.6 9.1 13.6 12.2 11.1 12.4 11.1 6.0 14.3 12.1 7.4 9.3 14.4 6.9 10.0 15.2 11.1 6.1 18.0 9.3 9.2 17.3 14.2 6.8 9.0 10.2 7.4 9.7 14.3 12.1 10.6 8.8 9.8 6.7 10.9 9.6 24.0 5.7 14.5 7.8 28.1 17.2 14.2 9.8 6.6 9.9 7.3 9.3 10.0 13.8 2.5 9.7 12.2 7.6 4.9 4.5 6.1 9.5 6.1 19.4 5.6 7.3 9.5 9.4 2.7 5.6 14.5 6.3 6.2 11.1 14.2 8.3 8.8 5.1 12.9 6.5 88.7 10.0 2.2 7.3 29.1 18.2 11.4 11.2 12.4 6.0 24.4 11.6 10.2 12.1 3.3 10.3 20.9 13.5 5.1 8.1 9.5 7.7 4.2 2.8 29.1 23.6 11.7 11.2 2.3 7.6 27.2 10.1 16.5 15.0 9.3 12.3 11.4 10.2 11.2 8.8 11.2 10.7 9.1 34.5 15.6 10.9 6.8 18.0 9.0 12.7 14.2 13.8 15.8 13.6 12.2 14.3 12.1 15.2 10.2 12.1 24.0 10.1 6.4 12.5 241.9 8.6 5.1 9.9 4.7 12.5 22.6 4.4 4.1 11.4 7.2 9.3 16.5 10.4 6.8 9.3 4.1 9.8 4.7 44.2 20.4 26.1 8.6 7.2 13.2 298.7 3.5 5.5 7.8 5.6 9.1 15.9 11.1 11.7 10.8 4.3 3.3 299.2 4.9 6.1 10.0 2.5 282.3 7.5 5.3 1.8 244.5 8.2 33.3 5.2 285.0 552.6 3.6 5.2 21.1 11.1 2.9 6.0 25.2 35.6 14.2 13.1 7.1 21.2 16.3 6.6 6.8 5.5 7.5 11.4 6.7 3.8 6.0 BCKDHA "MSU, OVD1A" ENSG00000248098 "Branched chain keto acid dehydrogenase E1 subunit alpha" P12694 19 41397808-41425002 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.2;Gastric mucus-secreting cells: 23.4;Plasma cells: 25.0;Squamous epithelial cells: 27.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036640 Supported NA NA 7700 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "HPA036640: AB_10671964" "unprognostic (4.50e-2)" "unprognostic (6.85e-2)" "unprognostic (1.14e-1)" "unprognostic (8.58e-3)" "unprognostic (1.26e-2)" "prognostic favorable (9.37e-4)" "unprognostic (2.41e-2)" "unprognostic (8.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.53e-1)" "prognostic favorable (5.33e-10)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.27e-5)" "unprognostic (9.66e-2)" 33.8 78.4 32.0 19.3 35.5 32.4 25.2 37.0 39.3 24.6 37.0 20.9 19.9 17.9 14.1 65.1 28.8 15.4 90.4 32.5 35.1 44.3 110.0 22.4 24.5 34.4 33.8 25.4 46.1 56.3 24.0 19.0 36.2 23.8 15.0 21.7 40.9 23.1 110.0 31.8 18.7 12.7 33.9 24.4 52.5 27.1 35.7 27.0 41.7 122.0 21.2 21.7 31.9 40.0 42.7 75.1 14.2 44.1 22.2 12.8 17.1 11.9 25.3 24.4 29.9 18.2 36.0 34.6 23.7 15.1 11.0 17.1 15.0 25.9 12.1 36.0 41.0 27.1 35.2 21.3 51.5 25.5 17.7 27.6 37.6 16.9 38.2 36.0 45.0 50.9 25.9 68.9 17.6 41.5 28.0 20.0 12.8 61.1 21.1 27.1 22.8 89.6 29.8 19.8 32.5 38.6 39.6 84.7 34.1 12.1 45.4 81.0 29.3 22.2 23.0 12.0 22.0 131.9 55.1 34.1 81.8 56.6 24.6 61.4 149.4 59.7 49.5 123.9 56.7 46.0 47.0 49.1 154.6 49.5 43.2 44.9 46.4 82.4 95.5 62.6 63.9 125.6 32.0 35.5 37.0 39.3 32.5 35.1 34.4 33.8 36.2 33.9 35.7 40.0 0.6 0.0 13.1 4.9 10.0 0.3 0.1 2.6 26.2 0.2 1.5 0.4 0.1 1.5 5.3 5.5 0.0 1.9 0.9 3.8 3.9 14.7 0.7 0.5 0.6 2.4 6.1 15.5 5.8 11.8 1.7 3.7 23.4 0.7 5.1 0.4 2.5 2.4 2.7 0.0 6.2 7.6 8.2 2.2 0.8 0.9 0.6 6.6 3.6 3.7 12.4 0.4 5.2 4.0 5.7 8.4 3.8 0.4 25.0 0.2 6.7 2.3 1.2 1.2 0.0 0.2 3.6 1.8 0.9 27.2 0.9 2.1 6.3 0.3 7.3 0.1 BCO2 "B-DIOX-II, BCDO2, FLJ34464" ENSG00000197580 "Beta-carotene oxygenase 2" Q9BYV7 11 112175510-112224699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 47.2;liver: 52.3;retina: 55.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 410.8;Horizontal cells: 134.6;Rod photoreceptor cells: 254.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.9;HHSteC: 12.3;U-937: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061542 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA061542: " "unprognostic (2.92e-1)" "unprognostic (1.89e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-2)" "unprognostic (7.60e-3)" "unprognostic (1.88e-1)" "unprognostic (3.18e-2)" "unprognostic (6.40e-2)" "unprognostic (2.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.36e-4)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (1.07e-2)" "unprognostic (1.34e-1)" 3.8 21.3 4.9 0.3 5.8 0.2 0.8 5.0 9.3 2.2 10.0 2.6 0.5 1.6 1.0 3.4 9.7 5.1 47.2 4.8 6.4 2.5 52.3 1.7 0.4 7.4 6.7 1.3 1.1 0.3 4.4 3.8 7.0 1.9 0.5 55.9 0.9 0.9 21.4 1.1 1.7 1.1 5.9 1.1 0.9 3.0 6.5 0.3 2.5 14.3 0.8 2.3 4.6 8.3 0.1 1.0 0.4 0.6 0.4 0.4 0.0 0.3 0.2 0.1 0.5 0.0 5.9 0.4 0.5 0.6 0.6 1.2 0.0 0.2 0.4 0.1 0.1 0.7 0.5 0.4 12.3 0.4 0.2 0.1 2.3 0.1 0.3 1.1 0.0 0.1 0.1 0.3 0.1 0.0 0.5 1.3 0.1 0.6 0.2 0.3 0.1 0.2 0.2 0.2 0.5 0.2 0.4 0.2 0.0 0.1 0.3 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.0 2.6 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 4.9 5.8 5.0 9.3 4.8 6.4 7.4 6.7 7.0 5.9 6.5 8.3 1.7 3.2 3.1 10.1 2.0 3.3 20.3 8.6 6.8 12.6 2.2 1.5 51.3 58.6 8.2 5.5 410.8 0.3 4.4 5.0 0.0 3.7 3.1 26.5 3.0 4.5 8.3 0.0 50.7 2.1 0.4 16.3 1.1 1.2 5.7 4.0 16.4 83.1 1.0 134.6 51.5 1.6 2.0 2.8 3.8 2.4 4.1 7.9 1.8 47.8 3.7 13.9 7.2 7.1 51.3 1.6 2.6 3.8 1.2 10.3 18.2 1.3 67.6 254.6 0.0 5.0 3.8 8.3 2.5 1.8 3.1 0.7 5.2 6.8 3.5 8.7 BIVM FLJ20159 ENSG00000134897 "Basic, immunoglobulin-like variable motif containing" Q86UB2 13 102799119-102841533 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA050126 Approved Supported Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Nucleoplasm "HPA050126: AB_2681027" "unprognostic (8.86e-2)" "unprognostic (1.02e-1)" "unprognostic (3.55e-1)" "unprognostic (2.77e-1)" "unprognostic (1.19e-2)" "unprognostic (1.83e-3)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (1.91e-2)" "unprognostic (1.30e-1)" "unprognostic (6.89e-3)" "unprognostic (6.66e-2)" "unprognostic (1.97e-1)" "unprognostic (2.79e-2)" "unprognostic (2.73e-1)" "unprognostic (7.29e-2)" "unprognostic (3.33e-2)" 7.4 7.1 8.2 3.6 8.6 3.6 8.8 10.9 10.6 8.6 7.6 7.1 6.3 9.2 11.5 5.5 7.7 6.9 19.4 8.3 7.8 16.3 18.8 6.7 4.5 7.5 7.9 9.2 10.4 9.1 8.9 7.7 7.7 7.8 8.2 9.0 6.1 7.6 17.8 7.2 6.3 8.9 6.8 7.4 8.6 2.3 8.5 10.4 8.0 18.9 4.3 7.4 6.5 9.1 16.8 4.6 19.9 18.7 24.2 37.4 4.1 19.3 23.9 14.5 16.5 6.1 7.7 0.1 8.2 22.1 10.3 11.5 17.9 16.3 17.5 17.1 16.3 14.7 14.2 8.8 19.5 16.8 22.2 28.2 18.8 7.9 20.5 25.4 20.2 22.7 14.4 0.0 25.7 3.7 19.3 16.1 4.3 24.1 12.9 0.0 9.0 6.4 50.0 7.2 23.8 21.1 8.5 9.2 12.3 7.2 13.3 22.7 12.9 13.0 4.3 9.4 11.8 12.5 5.6 0.1 21.2 0.0 25.9 5.5 0.4 1.1 2.2 0.2 5.2 0.5 1.4 2.9 1.6 0.5 0.7 1.4 0.3 7.6 0.0 0.4 1.0 1.0 8.2 8.6 10.9 10.6 8.3 7.8 7.5 7.9 7.7 6.8 8.5 9.1 9.3 9.6 12.8 2.9 2.6 3.7 3.8 7.0 11.4 19.0 7.7 6.1 30.7 21.5 11.2 18.4 14.6 7.1 3.8 5.6 29.4 6.5 0.5 5.1 11.8 11.0 21.8 9.2 13.9 5.5 7.8 11.8 6.1 4.9 6.3 15.2 17.2 34.0 7.0 23.5 16.8 15.3 6.1 5.0 3.4 0.4 13.7 3.3 3.6 4.7 2.4 8.1 5.2 9.0 6.3 4.1 9.3 11.3 4.5 4.9 9.7 30.8 8.9 12.4 19.7 10.4 9.8 2.0 12.6 11.4 4.8 2.5 8.1 10.3 15.2 3.4 BOLA3 ENSG00000163170 "BolA family member 3" Q53S33 2 74135400-74147912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 173.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 313.2;Distal tubular cells: 352.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046393, HPA053162" Uncertain Supported "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear bodies, Mitochondria" Cytosol "HPA046393: , HPA053162: AB_2682063" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-2)" "unprognostic (4.23e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.86e-3)" "unprognostic (8.03e-2)" "unprognostic (1.60e-2)" "unprognostic (4.03e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (9.90e-5)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (4.40e-1)" 35.6 39.3 52.1 22.6 54.3 40.8 31.4 58.9 66.1 20.2 55.0 46.5 33.8 24.5 25.1 31.7 20.8 11.9 101.0 52.7 56.5 59.8 33.7 23.5 22.2 57.0 53.8 16.6 44.7 56.2 29.6 14.2 56.0 25.4 37.6 35.7 39.7 23.7 117.8 16.6 28.9 22.6 54.7 21.9 41.1 15.8 53.7 24.8 28.8 173.9 21.6 27.1 24.3 55.3 102.8 134.0 44.8 46.2 81.5 78.3 113.9 92.5 54.5 104.0 72.0 176.6 45.4 67.2 79.7 82.4 99.3 53.2 107.9 135.4 95.8 126.5 172.8 85.4 88.3 269.8 76.1 167.3 39.0 62.2 96.6 100.9 124.2 45.9 79.4 144.3 183.2 73.7 116.0 163.6 136.4 123.1 66.9 196.8 198.6 88.5 120.1 132.0 138.8 106.2 70.4 40.7 68.3 106.8 123.3 62.0 62.6 102.8 42.6 83.9 142.9 93.8 185.4 67.5 135.3 92.7 87.6 131.8 73.8 14.7 14.2 3.9 68.3 29.9 75.7 45.4 92.7 72.6 37.8 44.5 79.3 68.7 3.0 51.7 33.5 65.1 91.2 40.6 52.1 54.3 58.9 66.1 52.7 56.5 57.0 53.8 56.0 54.7 53.7 55.3 54.7 9.6 29.8 8.5 33.2 22.7 44.5 111.8 43.3 29.9 82.0 109.5 313.2 44.3 50.1 84.6 16.7 54.9 42.8 125.4 352.1 93.2 20.0 67.0 46.2 45.5 76.1 138.2 14.3 111.4 167.5 48.6 58.1 61.5 25.4 31.9 36.4 113.3 113.9 26.9 15.0 128.3 83.4 32.1 28.9 10.2 32.9 32.2 99.6 3.7 59.4 61.8 62.8 7.5 7.7 95.0 70.9 46.3 76.1 50.9 85.6 266.4 51.2 52.6 19.7 39.6 64.4 66.8 80.5 101.0 16.9 22.3 45.1 83.0 176.2 52.0 BRMS1L "BRMS1, FLJ39177, MGC11296" ENSG00000100916 "BRMS1 like transcriptional repressor" Q5PSV4 14 35826338-35932325 "Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046623 Uncertain Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA046623: AB_2679724" "prognostic unfavorable (5.78e-4)" "unprognostic (1.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.69e-3)" "unprognostic (2.66e-2)" "unprognostic (2.27e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (2.56e-2)" "unprognostic (2.02e-2)" "unprognostic (8.04e-2)" "unprognostic (6.50e-2)" "unprognostic (1.66e-1)" "prognostic favorable (6.55e-5)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (6.87e-6)" 6.2 10.1 8.3 3.8 9.0 2.6 6.2 7.6 11.2 6.0 5.4 5.1 3.2 6.3 5.5 6.4 5.1 4.2 11.6 8.9 7.8 8.9 6.1 4.8 3.0 7.4 8.2 7.2 3.0 9.8 4.4 7.3 7.9 6.5 3.6 8.2 4.2 6.2 13.6 5.9 3.1 7.0 7.7 3.5 4.3 5.3 8.2 3.5 7.2 13.7 3.9 5.8 5.4 9.4 10.1 10.1 17.1 9.9 15.2 19.1 25.5 10.3 9.9 15.7 15.3 6.5 8.3 8.1 10.3 14.4 7.4 12.6 13.7 18.7 22.3 9.0 16.8 7.4 10.1 28.6 10.7 3.7 5.9 13.4 12.5 12.1 10.2 8.2 11.4 4.7 3.6 6.3 17.7 13.5 4.3 6.0 6.8 14.2 14.8 4.4 19.1 6.2 12.7 11.4 5.1 13.1 12.0 13.7 12.2 13.0 15.7 5.2 7.0 14.9 9.1 8.6 10.2 5.8 8.2 5.0 3.7 8.1 9.2 0.0 0.5 0.3 1.0 1.2 0.8 0.7 1.0 1.3 0.3 0.5 1.4 1.2 0.0 0.4 1.4 0.9 1.4 0.7 8.3 9.0 7.6 11.2 8.9 7.8 7.4 8.2 7.9 7.7 8.2 9.4 11.6 9.6 13.9 13.7 10.5 18.6 10.2 10.4 19.9 18.5 8.4 7.1 19.2 2.8 10.6 7.3 4.2 19.3 15.7 2.3 7.9 4.9 3.5 6.7 13.0 11.2 4.8 1.3 21.2 6.9 15.4 15.3 6.1 6.3 14.7 6.9 6.8 6.3 5.1 16.8 22.3 3.8 12.2 2.8 9.5 3.2 11.1 3.9 8.8 6.5 6.6 21.4 3.1 20.6 26.2 4.4 3.0 9.8 8.8 14.0 1.7 19.2 6.7 17.5 19.7 17.5 20.0 6.5 16.6 12.6 16.2 22.4 11.4 11.8 3.7 7.1 C16orf91 "CCSMST1, gs103, URLC5" ENSG00000174109 "Chromosome 16 open reading frame 91" Q4G0I0 16 1419752-1420756 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.97e-2)" "unprognostic (4.62e-2)" "unprognostic (4.11e-3)" "unprognostic (6.35e-2)" "unprognostic (2.11e-1)" "unprognostic (2.10e-1)" "unprognostic (5.47e-3)" "unprognostic (5.21e-2)" "unprognostic (1.12e-2)" "unprognostic (1.26e-1)" "unprognostic (4.33e-1)" "unprognostic (7.12e-2)" "prognostic favorable (1.11e-4)" "unprognostic (9.81e-3)" "unprognostic (5.67e-2)" "unprognostic (4.19e-2)" "unprognostic (9.97e-2)" 7.2 14.4 13.3 4.4 13.7 8.0 7.6 13.5 14.5 6.2 14.2 8.7 7.7 7.1 5.8 9.9 7.9 4.6 12.5 13.9 13.6 10.2 12.4 5.2 8.0 13.5 13.2 6.4 8.4 7.7 5.2 7.0 13.8 6.5 6.2 5.8 6.2 7.6 14.0 10.6 7.6 6.3 13.1 8.0 8.2 7.9 13.6 10.1 5.6 16.0 7.7 7.9 6.6 13.6 16.6 31.4 11.3 11.9 18.1 13.6 13.4 12.9 13.8 23.3 19.4 30.3 26.2 15.7 18.8 15.1 17.4 16.6 20.6 21.5 12.9 15.7 29.6 8.9 31.3 24.3 24.7 24.3 12.0 14.9 35.1 22.2 23.5 11.1 19.4 27.1 27.4 25.2 13.8 42.3 20.7 21.3 19.4 26.4 23.0 32.6 11.1 39.1 19.5 8.8 13.9 19.4 16.6 26.1 17.4 7.5 23.8 46.6 12.2 12.1 9.3 9.5 14.6 17.5 20.8 31.2 10.3 15.8 14.6 27.1 23.5 12.5 31.7 23.2 34.0 42.9 28.8 24.5 26.9 32.9 33.6 26.6 12.8 40.2 15.8 37.6 25.2 18.1 13.3 13.7 13.5 14.5 13.9 13.6 13.5 13.2 13.8 13.1 13.6 13.6 20.5 6.4 6.7 3.3 21.8 44.4 26.8 36.7 25.0 13.8 30.8 34.7 13.8 21.5 21.1 7.3 12.5 33.8 27.0 22.3 45.0 23.4 3.9 21.4 20.5 21.0 15.6 21.2 5.8 20.7 26.9 16.6 13.7 19.6 15.2 23.2 13.9 21.6 21.6 13.5 5.4 23.5 26.4 10.9 15.7 2.0 13.1 11.2 16.0 1.0 23.7 26.3 25.7 4.0 5.0 22.6 16.6 11.3 21.3 39.8 21.0 25.0 29.6 25.2 13.1 21.9 18.5 20.7 22.5 35.8 61.1 36.9 22.3 30.8 29.1 30.1 C19orf53 "HSPC023, LYDG10" ENSG00000104979 "Chromosome 19 open reading frame 53" Q9UNZ5 19 13774456-13778773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059928, HPA061291" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "HPA059928: AB_2684165, HPA061291: AB_2684469" "unprognostic (3.94e-2)" "unprognostic (2.70e-3)" "unprognostic (6.53e-2)" "unprognostic (3.12e-1)" "unprognostic (1.99e-2)" "unprognostic (8.93e-2)" "unprognostic (2.93e-3)" "unprognostic (2.77e-2)" "unprognostic (1.32e-1)" "unprognostic (2.96e-2)" "unprognostic (1.67e-1)" "unprognostic (6.31e-2)" "unprognostic (1.60e-3)" "unprognostic (5.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.69e-3)" "unprognostic (1.85e-2)" 95.6 117.7 154.3 52.1 157.8 80.4 88.9 161.0 209.6 97.0 148.4 94.3 45.4 91.6 85.6 92.3 87.6 49.8 155.6 154.4 163.8 124.4 111.0 80.1 76.9 159.4 159.9 111.7 95.5 92.8 111.6 40.2 157.8 98.8 41.6 35.7 76.9 52.8 167.6 95.2 72.4 63.0 157.5 82.1 91.2 51.6 158.0 101.5 90.4 107.2 70.8 88.6 82.6 157.3 176.4 249.9 123.0 98.9 169.6 191.1 80.1 167.0 145.5 201.0 200.7 235.8 83.5 95.4 198.2 202.4 146.6 90.1 111.6 250.1 102.7 113.5 362.3 90.1 254.6 260.5 174.9 140.7 109.4 237.8 174.7 188.1 105.9 129.0 171.0 136.6 140.9 154.2 157.9 406.2 193.6 145.9 152.6 133.8 441.8 105.7 94.9 160.5 177.1 221.3 108.6 132.4 115.1 130.8 172.5 89.2 120.0 139.0 118.4 221.9 89.2 239.4 227.5 172.3 240.3 144.4 132.3 157.6 121.8 264.1 220.1 275.7 211.0 238.2 240.4 333.2 270.7 248.4 202.2 321.1 318.1 289.7 107.1 184.7 214.3 289.4 337.9 496.3 154.3 157.8 161.0 209.6 154.4 163.8 159.4 159.9 157.8 157.5 158.0 157.3 167.0 115.4 97.8 13.7 205.2 291.1 260.1 349.2 147.4 50.5 258.7 352.9 263.3 213.1 207.8 268.5 22.9 218.6 176.5 230.1 628.0 242.5 176.8 229.3 189.8 194.4 227.3 174.0 10.5 335.2 406.3 184.4 109.6 233.0 128.7 132.4 179.9 367.5 368.2 35.3 10.2 254.3 236.0 247.1 287.1 621.4 218.7 187.5 231.3 5.6 338.9 220.3 260.6 6.6 18.8 269.6 272.8 182.4 164.1 360.5 353.9 820.0 189.3 65.9 92.1 138.5 206.0 102.6 137.0 187.7 348.5 213.0 216.0 169.8 257.5 345.2 C3orf18 G20 ENSG00000088543 "Chromosome 3 open reading frame 18" Q9UK00 3 50558025-50571027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.3;Early spermatids: 54.2;Late spermatids: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;NK-cells: 2.0;T-cells: 6.3" "Cell line enhanced" "Detected in many" "HDLM-2: 48.8" "Group enriched" "Detected in all" 4 "cerebellum: 28.2;olfactory bulb: 27.5" "Low region specificity" "Detected in all" HPA012105 Approved Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA012105: AB_1845717" "unprognostic (9.29e-3)" "unprognostic (1.46e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (8.19e-2)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (1.05e-2)" "unprognostic (1.64e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-3)" "unprognostic (1.29e-2)" "prognostic favorable (2.80e-9)" "unprognostic (7.65e-2)" "unprognostic (4.49e-1)" "unprognostic (2.18e-1)" "unprognostic (1.59e-1)" 6.1 8.7 23.0 2.9 23.6 0.9 5.6 30.0 24.0 10.8 25.8 11.9 1.8 10.6 4.4 3.5 9.3 3.6 33.3 22.2 25.6 9.4 4.9 3.7 3.8 23.6 24.9 12.6 6.6 27.3 12.5 2.1 23.2 9.2 2.6 28.4 7.1 9.8 36.2 3.1 5.3 9.5 22.8 5.2 10.1 19.7 25.1 3.1 9.0 26.8 3.6 9.5 6.4 22.1 1.8 2.7 3.1 0.6 10.1 9.0 1.0 11.1 17.2 9.9 7.2 0.2 2.8 2.3 2.6 15.2 9.3 0.2 0.0 4.3 5.2 48.8 0.3 5.0 6.9 0.8 5.0 0.0 6.0 8.9 0.6 9.6 0.5 7.9 1.9 7.2 1.1 2.2 5.9 0.4 0.4 1.5 3.8 1.9 12.3 1.0 0.3 2.7 0.6 0.4 3.4 16.1 2.9 0.6 0.3 3.5 3.4 1.3 0.6 9.9 7.7 18.1 1.4 2.8 2.5 0.3 14.0 5.1 0.2 0.0 0.4 0.7 5.1 0.1 6.3 2.2 4.3 4.8 0.4 1.4 5.0 6.1 0.0 2.0 0.1 0.8 2.2 2.5 23.0 23.6 30.0 24.0 22.2 25.6 23.6 24.9 23.2 22.8 25.1 22.1 1.8 0.0 1.1 8.1 2.2 1.1 1.1 0.9 1.2 10.2 1.8 2.0 29.3 0.0 1.4 1.8 8.4 0.4 1.3 0.3 3.9 2.1 54.2 1.1 2.3 2.6 1.8 0.0 5.6 1.8 0.8 4.9 1.5 0.5 0.0 3.1 2.5 2.2 1.6 1.7 8.3 0.7 0.0 1.3 0.3 62.6 4.7 1.1 0.0 3.7 8.9 12.4 3.1 3.0 3.3 0.7 0.1 4.1 1.6 0.5 0.1 3.5 1.2 17.3 13.1 5.6 5.3 2.7 2.5 0.1 0.4 0.1 3.0 2.7 0.3 0.2 CAMTA1 KIAA0833 ENSG00000171735 "Calmodulin binding transcription activator 1" Q9Y6Y1 1 6785454-7769706 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036342, HPA036343" Approved Supported Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA036342: AB_2675072, HPA036343: AB_10671839" "unprognostic (1.11e-1)" "unprognostic (6.31e-2)" "unprognostic (5.80e-2)" "unprognostic (4.14e-3)" "unprognostic (3.10e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "prognostic favorable (4.10e-4)" "unprognostic (3.90e-3)" "unprognostic (8.84e-2)" "unprognostic (1.35e-3)" "unprognostic (2.17e-2)" "unprognostic (9.19e-3)" "unprognostic (1.42e-1)" "unprognostic (9.03e-3)" 37.1 43.7 56.2 23.6 55.3 26.5 38.7 63.4 75.8 33.0 29.4 71.8 52.8 40.1 81.7 37.5 36.0 30.4 114.0 55.0 68.6 68.4 70.5 36.7 27.3 69.4 66.0 35.4 26.4 43.3 35.5 26.4 68.7 47.0 48.5 68.2 50.5 50.5 101.6 26.0 41.1 42.4 61.5 30.7 45.2 44.5 66.4 31.9 52.0 104.7 33.5 56.5 35.2 60.8 67.6 37.2 101.2 51.7 51.2 77.6 28.4 71.0 54.7 75.3 63.1 45.1 83.2 55.5 54.6 75.2 50.3 40.8 53.6 73.7 106.5 41.8 57.8 62.7 85.1 89.6 83.0 48.2 43.6 52.5 50.2 54.5 83.0 64.6 85.1 77.7 44.8 73.2 87.9 65.0 64.6 130.9 70.2 85.2 43.2 42.5 90.2 123.7 103.4 38.7 104.2 83.7 50.4 74.1 113.9 72.3 40.2 59.4 50.1 53.1 44.9 55.3 45.2 55.2 74.3 153.2 79.6 107.4 30.7 80.1 74.7 70.5 25.8 48.5 28.3 48.1 39.8 32.0 73.4 41.8 32.2 28.1 15.4 26.7 37.9 77.5 45.6 46.3 56.2 55.3 63.4 75.8 55.0 68.6 69.4 66.0 68.7 61.5 66.4 60.8 142.1 54.5 48.8 314.7 74.3 309.7 340.6 306.6 169.0 106.7 231.7 283.2 565.2 101.5 135.3 191.3 252.3 69.8 44.3 198.3 418.7 180.1 166.1 84.1 80.3 155.8 130.8 81.8 346.1 206.3 144.9 134.4 63.2 99.8 55.2 205.4 106.1 239.0 106.3 158.2 479.3 185.8 223.8 95.5 254.0 137.9 76.4 122.0 238.3 117.1 172.9 112.3 38.1 330.3 227.5 184.2 234.5 128.6 87.9 486.4 251.7 750.7 117.1 156.2 138.1 91.1 233.2 151.0 211.0 158.9 282.7 88.1 68.2 137.8 186.5 413.7 CASD1 "C7orf12, FLJ21213, FLJ21879" ENSG00000127995 "CAS1 domain containing 1" Q96PB1 7 94509219-94557019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.7;Inhibitory neurons: 108.5;Oligodendrocyte precursor cells: 122.6;Oligodendrocytes: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044404 Uncertain Approved Nucleoplasm Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA044404: AB_10964353" "unprognostic (4.02e-2)" "unprognostic (4.16e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (7.04e-2)" "unprognostic (7.90e-2)" "unprognostic (3.66e-2)" "unprognostic (2.18e-2)" "unprognostic (9.83e-2)" "unprognostic (4.74e-2)" "unprognostic (4.95e-3)" "unprognostic (2.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (1.93e-1)" "unprognostic (7.07e-2)" "unprognostic (2.59e-3)" 11.1 25.3 11.4 9.6 14.0 6.0 15.7 11.1 12.9 11.3 4.8 16.5 6.5 14.1 14.6 6.3 11.0 10.0 17.1 14.9 17.4 12.4 9.0 11.3 12.5 8.8 10.7 16.4 9.8 13.8 8.7 12.3 12.9 13.9 19.3 22.1 20.3 9.4 14.1 3.8 6.1 11.0 11.3 10.6 7.3 13.1 14.6 11.2 16.0 19.6 10.8 9.1 4.3 14.0 5.5 10.4 34.7 12.9 10.4 12.3 5.9 7.2 12.8 7.9 10.2 6.5 13.2 13.9 18.5 9.8 14.1 3.0 8.8 2.5 15.4 22.2 7.1 12.3 8.5 11.9 8.8 20.5 0.0 11.4 9.2 7.2 10.3 15.4 12.6 16.0 6.7 29.3 19.6 8.0 28.5 11.6 17.7 7.7 8.2 19.3 28.0 10.8 15.9 14.9 13.1 44.5 11.4 20.7 7.4 24.9 5.4 12.8 6.7 19.6 15.5 16.2 10.6 28.0 28.1 28.5 10.7 4.7 12.9 0.0 0.2 0.0 0.6 0.2 1.6 0.6 0.9 0.8 0.4 0.5 0.9 0.7 0.0 0.6 0.2 0.3 0.6 0.2 11.4 14.0 11.1 12.9 14.9 17.4 8.8 10.7 12.9 11.3 14.6 14.0 26.2 28.9 26.3 76.0 15.4 4.6 5.8 5.8 4.0 56.4 14.4 12.8 21.1 17.2 12.8 20.2 18.8 14.2 14.6 29.7 3.9 5.1 3.4 18.0 13.1 16.4 7.2 4.6 93.7 5.6 5.7 14.6 5.1 9.9 10.2 23.7 16.1 13.3 8.8 67.3 108.5 30.2 2.0 9.8 5.5 7.0 11.5 10.8 24.9 61.8 7.1 23.3 10.3 122.6 170.3 6.8 11.8 9.8 9.2 10.0 0.6 10.8 18.1 31.4 19.7 41.2 12.2 9.6 12.8 4.7 4.5 16.8 12.2 25.8 19.5 4.5 CCDC124 ENSG00000007080 "Coiled-coil domain containing 124" Q96CT7 19 17933015-17943991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041708, HPA046765" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA041708: AB_2677628, HPA046765: AB_2679793" "unprognostic (9.39e-2)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.32e-2)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (1.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.19e-1)" "unprognostic (3.71e-2)" "unprognostic (3.22e-1)" 82.9 67.6 62.4 32.0 62.9 42.7 78.0 64.1 104.5 77.3 54.0 115.7 25.6 78.6 7.1 100.3 67.8 11.2 131.9 61.9 60.7 88.5 88.0 70.8 22.7 63.2 62.1 64.9 72.2 22.1 55.7 20.3 64.8 77.9 8.4 9.0 69.3 22.2 210.2 92.8 58.5 14.2 57.3 67.5 81.2 48.5 66.0 17.7 65.6 38.3 12.2 84.5 80.9 68.2 242.7 165.3 54.2 111.3 35.4 26.9 178.8 118.9 36.7 59.0 49.8 125.0 97.1 182.8 166.7 47.5 38.8 90.1 60.0 108.3 17.2 194.7 341.8 152.7 140.5 147.0 68.4 174.4 100.6 43.2 70.7 59.7 56.9 33.9 62.7 115.0 196.3 74.4 30.8 232.8 166.1 212.3 126.3 79.2 282.2 163.2 103.6 195.1 48.9 85.7 108.6 155.8 83.4 92.4 121.3 22.0 86.2 62.6 142.0 102.3 128.1 198.0 185.6 102.8 121.7 178.5 128.6 203.1 133.0 81.1 82.2 73.5 85.9 95.1 69.2 61.0 66.8 80.8 85.5 66.4 51.8 63.5 20.5 76.3 71.3 75.4 84.1 66.2 62.4 62.9 64.1 104.5 61.9 60.7 63.2 62.1 64.8 57.3 66.0 68.2 58.8 19.2 4.8 8.1 41.1 90.5 60.0 115.9 44.9 22.9 49.3 57.3 15.6 35.8 58.7 73.5 2.1 93.8 44.1 108.9 137.0 146.2 33.4 46.7 50.9 57.3 61.0 79.8 7.4 199.0 140.2 58.1 79.0 56.5 27.3 73.9 50.7 57.1 110.3 10.1 6.4 89.0 101.7 60.0 73.2 106.1 32.6 50.3 96.0 4.7 86.4 50.9 50.4 4.5 7.1 227.9 70.0 41.3 68.7 108.7 78.5 142.3 44.8 23.1 19.7 43.4 76.0 30.9 39.9 79.6 109.8 82.8 42.8 184.7 88.6 73.5 CCDC51 FLJ12436 ENSG00000164051 "Coiled-coil domain containing 51" Q96ER9 3 48432164-48440456 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010980, HPA011408" Supported Supported Nucleoplasm,Centrosome,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Centrosome "HPA010980: AB_1846155, HPA011408: AB_2072212" "unprognostic (1.24e-2)" "unprognostic (5.23e-2)" "unprognostic (5.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (3.50e-1)" "unprognostic (2.75e-3)" "unprognostic (4.71e-3)" "unprognostic (1.26e-2)" "unprognostic (3.04e-1)" "unprognostic (3.26e-2)" "unprognostic (7.70e-2)" "unprognostic (1.47e-3)" "unprognostic (6.46e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" 10.1 13.7 10.7 7.3 10.9 5.0 8.7 10.8 11.6 8.3 22.2 12.2 11.0 8.0 10.1 13.8 8.8 5.4 11.9 11.1 10.6 13.9 13.0 6.7 9.6 11.3 10.8 7.7 5.4 9.4 6.1 8.2 11.3 6.7 13.6 7.7 7.0 9.0 15.5 10.1 8.6 9.0 10.7 12.6 7.6 7.8 11.7 9.9 10.3 11.7 11.8 9.0 9.5 10.7 22.7 26.7 15.7 18.7 23.1 24.2 43.6 14.6 13.4 28.6 23.2 42.9 36.9 48.6 20.5 11.7 21.6 32.2 39.5 47.8 17.4 22.9 25.6 41.4 44.1 32.7 35.3 20.4 18.2 18.4 106.8 35.6 38.8 15.7 16.7 28.0 23.4 13.7 27.7 21.4 24.1 26.5 34.8 48.2 42.8 16.5 18.6 37.7 39.3 27.8 13.1 27.2 24.2 26.2 39.9 14.7 28.2 31.3 12.6 16.5 22.3 41.6 28.5 22.0 34.8 25.5 22.0 43.8 16.0 3.0 14.1 7.0 15.5 14.9 15.8 28.1 14.5 19.7 25.5 23.0 14.8 17.4 6.0 16.5 9.1 21.1 19.8 14.6 10.7 10.9 10.8 11.6 11.1 10.6 11.3 10.8 11.3 10.7 11.7 10.7 7.1 12.8 2.6 2.6 5.9 4.7 3.7 28.8 17.6 7.3 6.6 8.1 8.2 15.7 12.8 9.2 0.0 40.1 5.0 12.6 23.5 15.1 3.3 19.4 7.3 5.9 5.4 5.9 2.4 12.4 22.0 10.0 6.6 16.5 3.8 10.1 4.6 13.1 15.9 8.4 2.4 7.6 14.2 3.8 3.3 2.7 12.2 4.4 14.2 1.9 9.1 11.0 11.3 3.5 3.2 15.2 8.0 13.2 5.1 5.4 21.6 43.4 9.3 10.7 6.6 4.0 6.2 7.2 16.3 13.0 4.7 6.7 4.8 20.0 13.4 3.4 CCNQ "CycM, FAM58A" ENSG00000262919 "Cyclin Q" Q8N1B3 X 153587925-153600045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 72.4;Extravillous trophoblasts: 98.6;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050137, HPA059843" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "HPA050137: AB_2681029, HPA059843: AB_2684140" "unprognostic (3.94e-1)" "unprognostic (1.94e-2)" "unprognostic (7.36e-2)" "unprognostic (2.92e-1)" "unprognostic (5.08e-2)" "unprognostic (1.02e-2)" "unprognostic (1.47e-3)" "unprognostic (2.12e-1)" "unprognostic (8.50e-3)" "unprognostic (2.08e-2)" "unprognostic (1.57e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (8.75e-2)" "unprognostic (2.31e-1)" "unprognostic (2.71e-2)" "unprognostic (5.25e-2)" 11.8 12.8 19.9 8.2 21.3 7.3 11.7 19.6 24.9 11.9 15.6 16.2 8.9 12.9 12.7 13.1 11.1 4.0 33.9 20.8 20.5 13.5 13.2 10.6 12.5 23.2 21.6 10.5 15.0 10.3 23.6 9.2 23.4 13.6 8.0 6.4 12.9 8.8 34.3 12.1 13.6 6.1 20.0 17.2 13.3 6.2 21.2 9.0 11.1 13.6 12.2 14.0 11.7 24.9 43.7 31.2 12.1 43.5 20.9 11.2 18.7 25.0 21.8 23.5 23.6 33.3 14.3 34.9 44.6 25.1 35.3 26.7 38.4 22.6 22.2 20.3 39.2 7.8 19.4 23.5 19.0 28.2 18.9 14.1 20.1 15.7 16.1 10.0 19.0 16.1 10.6 15.6 19.1 50.5 19.7 38.0 15.1 44.4 52.4 22.6 20.0 17.8 17.0 17.6 16.0 21.1 12.0 19.3 34.4 11.9 7.3 25.0 14.6 20.5 29.3 46.7 38.5 21.8 23.1 43.4 18.5 45.4 15.7 0.0 1.6 4.9 2.7 1.4 1.0 6.1 2.3 1.9 1.3 4.1 2.5 1.7 0.9 0.7 0.8 1.2 3.4 1.1 19.9 21.3 19.6 24.9 20.8 20.5 23.2 21.6 23.4 20.0 21.2 24.9 21.0 3.2 13.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 24.1 31.0 0.0 0.0 3.1 7.3 0.0 40.7 20.4 0.0 72.4 23.3 0.0 11.9 17.3 7.8 0.0 0.0 0.0 37.1 98.6 8.4 0.0 8.7 2.5 16.3 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 22.7 0.0 0.0 0.0 0.0 34.0 0.0 0.0 5.9 0.0 0.0 41.6 2.2 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 120.9 10.0 18.4 0.0 0.0 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 35.1 36.7 52.0 13.3 51.2 34.5 34.2 51.5 63.0 36.9 47.5 62.5 17.8 33.5 14.1 40.5 33.6 10.1 80.0 52.7 48.7 32.1 88.0 32.1 12.5 51.0 50.7 35.6 58.5 18.7 43.4 29.2 50.8 36.9 11.5 28.2 34.2 19.3 105.0 51.8 27.6 18.5 48.2 31.0 38.6 100.2 52.7 16.4 26.7 63.2 9.7 43.7 34.2 52.7 54.8 54.6 66.4 54.7 29.2 28.4 68.5 47.8 36.1 50.2 51.9 86.1 32.8 29.5 49.3 34.1 30.1 36.9 52.1 40.2 25.0 49.2 146.0 27.8 35.5 94.5 73.6 39.0 32.4 36.4 58.9 42.2 43.6 38.8 60.6 41.2 120.3 57.5 33.8 80.7 53.3 53.6 85.3 39.4 51.7 49.1 35.1 51.2 38.0 32.4 87.2 65.9 41.5 42.1 85.2 53.2 34.0 57.4 50.5 36.5 43.7 86.2 65.2 57.7 47.3 40.1 50.0 55.6 38.8 3.2 2.5 4.7 1.6 2.7 1.1 2.3 2.1 2.9 2.0 1.0 1.6 1.6 8.2 1.2 3.5 1.6 2.5 1.0 52.0 51.2 51.5 63.0 52.7 48.7 51.0 50.7 50.8 48.2 52.7 52.7 39.4 0.0 5.4 21.9 11.4 46.8 17.5 5.4 16.5 35.5 43.4 47.1 27.7 27.1 3.5 14.7 25.0 44.3 30.9 47.4 13.7 24.9 63.9 29.6 28.3 27.7 13.2 77.7 8.3 20.5 55.4 21.4 16.8 42.3 0.0 28.1 15.7 41.1 27.9 16.8 6.3 34.0 14.2 14.5 38.6 249.4 18.0 20.6 19.6 2.8 15.1 68.9 20.6 6.6 12.9 45.0 27.0 15.1 25.0 34.8 25.9 18.9 5.5 44.3 13.1 22.6 34.9 22.4 54.6 15.2 54.7 63.1 22.0 27.1 23.7 27.9 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 217.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Microtubules, Cytosol" "Plasma membrane" "CAB016535: AB_785112, HPA000974: AB_2666162, HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 48.2 61.3 59.0 30.4 63.6 65.7 38.6 63.8 75.0 37.9 35.7 41.4 34.2 37.5 19.7 60.7 37.6 23.8 113.3 64.3 46.5 62.7 35.0 41.6 24.3 57.2 52.4 45.3 43.1 50.6 41.7 37.9 54.9 37.2 29.6 33.6 43.9 30.4 217.6 41.9 36.3 37.7 39.6 34.0 39.1 55.2 74.3 29.9 50.3 180.4 26.5 34.2 36.8 60.6 177.6 132.5 124.8 185.0 89.5 76.2 124.2 82.4 100.7 122.3 90.5 150.2 83.3 42.1 51.2 148.1 225.7 97.7 134.3 174.7 81.8 50.9 212.6 46.0 193.8 118.8 115.7 48.7 103.0 95.5 109.6 173.8 207.4 101.7 111.0 43.7 69.6 69.7 108.4 153.1 42.7 111.1 97.9 66.3 141.8 44.9 98.8 74.4 91.7 137.7 105.0 79.4 223.2 169.9 86.5 144.4 152.0 59.3 112.9 81.1 131.4 125.4 99.8 54.6 58.2 41.8 71.4 223.0 93.1 2.6 7.8 7.5 3.7 9.3 4.9 3.4 5.0 6.0 9.7 9.8 4.3 4.6 3.2 5.5 8.4 11.3 5.5 6.1 59.0 63.6 63.8 75.0 64.3 46.5 57.2 52.4 54.9 39.6 74.3 60.6 18.8 0.0 6.1 7.2 20.2 32.5 33.0 30.6 33.6 23.5 38.2 26.8 43.3 21.5 22.1 31.3 4.2 25.7 20.1 67.2 54.8 33.7 26.5 41.2 24.5 21.8 28.1 20.6 12.5 37.0 45.2 24.0 46.4 57.7 5.7 27.8 19.2 16.7 25.3 30.3 15.8 34.3 32.6 19.5 30.8 94.8 17.1 23.5 33.8 2.8 12.6 17.1 9.2 3.5 7.8 48.4 46.1 13.2 31.9 48.3 45.1 34.7 17.9 14.6 0.0 19.1 22.6 27.6 17.5 64.2 34.7 26.0 21.5 30.0 48.6 63.3 CEBPZOS CEBPZ-AS1 ENSG00000218739 "CEBPZ opposite strand" A8MTT3 2 37196488-37216193 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053866 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA053866: AB_2682283" "unprognostic (2.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" "unprognostic (8.05e-3)" "prognostic unfavorable (1.72e-6)" "unprognostic (2.34e-2)" "unprognostic (2.40e-2)" "unprognostic (5.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (3.46e-7)" "unprognostic (3.69e-2)" "unprognostic (4.49e-2)" "unprognostic (2.03e-1)" "unprognostic (1.33e-2)" 22.3 46.5 23.6 15.0 24.7 25.4 22.4 26.4 32.7 23.9 25.6 28.8 23.8 23.4 38.5 24.3 23.9 17.7 42.5 26.4 24.9 35.9 27.9 17.8 22.7 24.7 24.0 28.3 22.9 24.9 31.1 22.0 24.8 29.9 22.6 28.1 26.1 18.2 53.4 23.9 22.5 20.2 23.1 20.6 24.5 22.7 24.5 18.3 26.0 37.3 19.6 24.0 22.0 27.9 59.9 19.4 41.1 32.9 42.5 47.0 39.4 43.2 39.3 27.2 19.8 18.5 26.4 20.7 22.9 42.8 36.2 33.7 22.4 32.9 33.4 55.3 47.1 56.2 21.6 29.0 38.2 70.5 29.4 49.6 44.0 37.1 42.1 36.7 44.3 21.4 42.6 28.9 45.3 11.9 17.2 67.6 60.2 47.6 29.5 51.4 55.8 47.2 48.6 15.9 43.4 42.6 33.4 54.0 43.5 22.1 23.9 41.2 39.0 29.1 35.9 43.2 38.1 53.0 0.5 44.1 54.0 41.2 42.5 32.4 23.0 21.2 27.3 26.4 32.2 34.1 31.1 29.2 22.8 26.9 38.5 34.9 8.8 23.2 20.6 49.2 23.5 22.3 23.6 24.7 26.4 32.7 26.4 24.9 24.7 24.0 24.8 23.1 24.5 27.9 46.6 54.5 40.9 13.7 37.7 0.0 51.6 0.0 51.2 46.5 37.6 38.9 43.0 27.1 21.1 38.6 18.8 83.0 43.6 25.7 92.0 46.8 76.0 59.1 35.7 27.9 17.5 30.1 14.7 33.7 50.7 35.6 41.3 41.4 17.1 30.3 27.5 27.4 44.5 32.0 19.5 32.6 0.0 27.7 0.0 18.2 47.2 34.7 0.0 18.7 39.9 59.8 46.4 13.6 27.1 41.8 31.0 44.4 30.4 38.9 54.2 92.1 27.0 56.2 46.0 31.0 33.0 115.8 58.8 48.5 0.0 69.1 37.8 33.4 33.1 41.6 CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 100.4;Spermatogonia: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 106.4;JURKAT: 105.1;NTERA-2: 103.4" "Low region specificity" "Detected in all" "HPA042529, HPA042616" Enhanced Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Midbody, Cytosol" "HPA042529: AB_10793882, HPA042616: AB_10794050" "unprognostic (7.64e-2)" "unprognostic (4.41e-2)" "unprognostic (5.92e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (6.47e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-2)" "unprognostic (7.73e-3)" "unprognostic (7.93e-2)" "unprognostic (4.09e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-2)" "unprognostic (2.54e-2)" "unprognostic (3.60e-3)" 4.0 4.7 11.7 0.6 11.3 5.1 4.6 9.3 11.7 4.4 7.1 9.1 9.8 5.9 3.5 0.5 6.6 1.3 5.6 11.9 13.2 3.4 10.7 2.6 1.2 11.6 11.0 6.2 4.0 3.9 7.0 1.2 10.0 3.1 8.0 4.0 1.5 4.0 21.1 0.8 10.6 4.0 11.6 1.1 13.2 10.3 11.4 17.1 2.4 9.5 1.2 4.2 1.7 11.9 10.7 20.4 106.4 53.4 3.0 2.7 18.2 8.7 8.6 26.5 20.0 20.5 4.7 42.5 17.0 6.5 4.9 3.2 69.3 0.6 16.8 0.0 85.9 10.1 5.0 41.1 29.2 10.1 0.0 7.6 2.8 31.6 18.7 3.0 15.2 105.1 17.4 0.0 8.0 1.8 80.2 34.2 103.4 69.1 0.0 57.1 4.1 4.9 6.1 15.4 56.8 43.9 22.2 0.3 5.2 48.6 0.3 24.8 1.0 0.0 8.6 1.2 0.0 0.0 0.0 24.9 0.0 14.0 0.6 0.0 0.0 1.3 0.1 0.0 0.0 1.4 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.7 11.3 9.3 11.7 11.9 13.2 11.6 11.0 10.0 11.6 11.4 11.9 13.3 0.0 2.7 3.9 13.7 1.0 29.7 0.5 4.6 40.0 22.5 31.6 4.2 30.0 4.4 1.8 4.2 19.6 19.6 43.0 31.3 7.5 16.3 2.6 32.4 5.0 39.4 12.6 18.9 23.3 22.1 9.2 59.1 2.7 5.7 39.7 1.8 50.1 6.0 11.8 21.8 63.0 0.0 1.4 0.7 9.0 8.7 4.6 8.8 3.7 2.0 45.9 13.4 19.6 11.7 17.8 83.9 11.7 10.7 38.0 100.4 43.5 2.5 15.0 26.3 4.2 17.9 81.6 124.2 2.5 2.6 6.4 10.7 8.7 78.9 45.0 CHCHD1 "C10orf34, FLJ25854" ENSG00000172586 "Coiled-coil-helix-coiled-coil-helix domain containing 1" Q96BP2 10 73782047-73783652 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 561.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039046 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "Nucleoli fibrillar center" "HPA039046: AB_10673234" "unprognostic (4.97e-2)" "unprognostic (1.90e-3)" "unprognostic (2.96e-1)" "unprognostic (1.31e-3)" "unprognostic (1.80e-1)" "unprognostic (9.85e-2)" "unprognostic (1.75e-2)" "unprognostic (3.33e-1)" "unprognostic (1.35e-1)" "unprognostic (2.24e-2)" "unprognostic (4.53e-1)" "unprognostic (1.91e-2)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (1.54e-1)" "unprognostic (5.58e-2)" "prognostic favorable (5.42e-4)" 30.1 53.2 38.7 29.3 39.1 26.7 34.4 40.0 45.1 25.4 41.9 38.1 40.0 25.9 52.0 49.8 25.6 18.5 52.9 38.9 39.6 55.9 54.7 25.6 36.4 38.8 38.5 24.1 31.3 42.8 31.0 29.2 39.2 36.7 29.0 21.9 45.6 21.9 64.2 29.9 35.1 19.1 39.3 40.3 37.6 24.8 39.4 34.6 31.9 50.6 30.8 27.7 30.1 40.1 115.8 87.6 70.8 98.3 57.0 56.6 71.1 58.3 70.7 59.8 80.0 78.6 99.3 56.9 63.3 52.9 60.1 77.9 69.8 79.8 46.9 87.6 132.4 42.7 73.2 119.6 68.6 65.8 65.7 52.3 96.3 51.5 33.0 87.4 83.9 78.8 67.0 61.7 78.3 117.3 82.1 146.5 66.3 109.6 561.7 77.3 53.9 72.6 97.5 63.0 34.2 67.4 36.0 246.2 127.3 56.8 138.0 92.5 47.2 35.7 79.7 60.2 102.4 61.5 70.7 91.2 83.4 133.7 28.5 44.2 51.3 32.5 36.1 54.9 43.9 62.6 43.7 43.5 52.5 50.8 36.1 36.9 21.2 36.6 45.6 75.1 65.2 35.8 38.7 39.1 40.0 45.1 38.9 39.6 38.8 38.5 39.2 39.3 39.4 40.1 45.0 41.7 48.4 5.2 50.7 35.1 34.4 117.2 29.0 27.0 68.7 74.4 77.3 47.1 84.4 60.7 22.9 151.6 49.3 112.1 199.6 80.8 73.3 99.0 64.1 44.5 61.8 61.2 8.6 88.3 166.3 38.2 41.8 75.8 29.8 63.9 51.4 132.5 139.7 20.2 8.0 106.2 122.1 61.2 35.6 16.3 56.5 52.7 40.9 5.6 82.5 76.8 51.5 5.5 9.6 96.4 96.4 55.3 53.3 55.3 101.0 243.3 99.0 35.3 52.6 36.1 52.4 70.1 48.7 71.2 43.5 128.1 41.6 83.9 98.4 54.9 CHCHD10 "C22orf16, MIX17A, N27C7-4" ENSG00000250479 "Coiled-coil-helix-coiled-coil-helix domain containing 10" Q8WYQ3 22 23765834-23767972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1622.6;skeletal muscle: 1220.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1264.7;Distal tubular cells: 2498.5;Hepatocytes: 1879.9;Proximal enterocytes: 1501.3;Proximal tubular cells: 1437.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003440 Enhanced Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003440: AB_1078348" "unprognostic (3.88e-2)" "unprognostic (2.36e-3)" "unprognostic (8.90e-2)" "unprognostic (9.80e-2)" "unprognostic (7.68e-2)" "unprognostic (5.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "unprognostic (2.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" "prognostic favorable (2.15e-7)" "unprognostic (5.19e-3)" "unprognostic (2.06e-1)" "unprognostic (5.68e-3)" "unprognostic (2.62e-3)" 216.5 136.5 181.6 30.3 188.3 12.5 144.5 183.0 248.9 77.3 262.6 261.2 92.6 35.5 32.4 147.3 43.1 10.9 1622.6 176.6 190.5 409.5 789.7 56.9 28.6 182.2 182.2 29.0 118.0 220.0 112.3 11.9 187.6 106.4 76.2 63.1 148.3 50.5 1220.9 71.8 159.0 17.9 169.5 100.3 160.2 27.8 204.8 14.0 224.7 660.7 34.5 110.2 89.1 179.3 33.1 66.4 19.7 85.9 42.1 27.7 41.9 11.9 22.8 23.5 28.4 124.1 35.1 113.5 30.7 41.2 12.9 99.8 109.2 34.1 20.5 35.9 140.6 22.5 48.8 117.1 73.8 63.6 108.2 53.3 91.9 35.6 9.3 4.9 29.0 17.2 47.7 48.0 20.6 121.8 21.8 48.2 16.9 194.9 183.5 90.0 4.0 209.0 112.7 55.3 41.3 23.8 13.9 145.7 149.7 36.6 54.9 47.0 15.3 1.0 1.1 18.3 0.2 28.8 11.1 62.5 20.5 54.9 11.2 0.2 4.1 11.2 3.0 9.1 1.9 11.7 3.2 4.0 1.8 10.6 4.9 3.5 0.0 0.8 8.2 7.3 4.3 1.2 181.6 188.3 183.0 248.9 176.6 190.5 182.2 182.2 187.6 169.5 204.8 179.3 88.7 12.8 10.5 36.2 294.8 48.2 415.4 28.2 144.5 136.2 156.9 238.2 503.8 268.8 20.5 419.3 114.7 42.5 104.7 1264.7 2498.5 88.1 27.0 76.6 229.8 47.4 310.5 74.3 38.5 54.5 255.7 67.8 300.7 94.3 84.0 171.9 78.1 1879.9 647.5 99.3 37.6 860.9 26.4 262.1 127.5 18.0 48.7 243.1 373.5 15.9 107.8 188.5 25.7 17.1 17.4 45.9 890.1 29.3 297.3 192.4 1501.3 1437.4 10.0 287.8 124.9 254.0 200.4 32.3 43.4 459.3 43.9 105.2 123.0 216.0 952.4 470.1 CHCHD2 "C7orf17, MIX17B, MNRR1" ENSG00000106153 "Coiled-coil-helix-coiled-coil-helix domain containing 2" Q9Y6H1 7 56101573-56106476 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Activator "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 3195.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027407, HPA052510" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA027407: AB_10959659, HPA052510: AB_2681856" "unprognostic (8.68e-3)" "unprognostic (2.79e-1)" "unprognostic (8.48e-2)" "unprognostic (2.32e-1)" "unprognostic (3.90e-2)" "prognostic unfavorable (1.90e-5)" "prognostic unfavorable (9.41e-5)" "unprognostic (4.38e-2)" "unprognostic (3.61e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-1)" "unprognostic (2.79e-2)" "unprognostic (2.60e-2)" "unprognostic (4.01e-2)" "unprognostic (1.79e-1)" "unprognostic (2.09e-1)" "unprognostic (2.40e-2)" 250.6 665.5 321.4 167.4 331.8 426.3 253.9 361.8 358.5 220.7 351.0 257.6 252.0 219.0 252.4 269.6 210.6 132.1 412.4 325.3 352.7 349.4 316.7 213.8 205.0 340.1 341.5 246.3 315.9 322.9 272.3 151.8 343.2 237.2 191.7 226.2 281.2 196.7 791.4 233.3 243.9 150.5 354.6 223.3 287.6 120.7 352.2 267.7 208.2 591.3 200.2 217.8 214.2 367.9 3195.8 553.5 351.8 732.5 275.9 379.3 261.7 456.7 436.2 584.6 561.3 513.0 517.4 932.1 589.1 285.1 741.3 527.6 456.5 507.4 469.6 609.1 831.5 549.2 422.0 738.9 510.5 745.9 844.8 339.1 571.9 438.0 532.4 312.3 444.1 800.3 1182.9 546.7 486.4 449.9 1007.2 2306.5 760.6 867.3 872.6 668.3 343.3 1539.3 532.5 417.0 671.5 834.3 360.6 874.7 597.1 239.4 1002.5 1046.8 354.2 354.2 823.5 1473.9 683.6 497.1 785.4 1698.9 555.3 802.0 448.0 354.1 509.1 400.6 362.1 458.7 377.4 461.2 387.4 387.2 575.8 435.0 344.9 354.9 268.0 400.9 467.1 785.2 550.9 1066.7 321.4 331.8 361.8 358.5 325.3 352.7 340.1 341.5 343.2 354.6 352.2 367.9 465.1 256.4 284.0 44.4 521.9 717.5 956.6 1072.0 387.0 348.7 758.3 929.8 160.8 513.3 612.1 413.8 62.6 955.1 577.6 807.9 1860.7 1034.0 167.2 593.3 396.0 446.5 541.2 666.1 26.7 1325.1 1259.9 514.7 393.0 622.8 394.3 458.8 377.0 727.2 969.6 492.9 35.6 973.0 752.7 483.5 701.2 213.4 614.2 496.2 763.1 28.1 806.5 769.6 593.2 19.6 43.2 1190.3 974.5 505.9 803.3 1321.7 1138.5 1558.4 559.1 353.7 427.3 620.2 583.8 520.4 574.2 680.8 719.3 1228.8 492.5 633.1 929.0 1464.2 CHCHD4 "FLJ31709, MIA40, TIMM40" ENSG00000163528 "Coiled-coil-helix-coiled-coil-helix domain containing 4" Q8N4Q1 3 14112077-14124870 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 84.1;Proximal tubular cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA034688, HPA063727" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034688: AB_10696361, HPA063727: AB_2685103" "unprognostic (3.89e-3)" "unprognostic (8.82e-2)" "unprognostic (1.50e-2)" "unprognostic (7.34e-2)" "unprognostic (1.11e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-3)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (5.55e-2)" "unprognostic (3.59e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.63e-5)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (9.65e-2)" "unprognostic (7.85e-3)" 12.2 14.0 12.3 8.6 12.9 3.3 11.5 12.8 16.4 9.8 13.3 19.5 14.6 8.9 10.1 12.4 9.6 5.8 25.8 12.4 14.4 20.9 18.8 7.6 8.9 13.0 13.8 10.4 11.1 22.9 9.6 8.5 13.0 10.8 15.5 11.4 10.1 11.8 34.1 10.3 11.5 8.8 12.5 10.3 13.6 8.7 12.7 9.4 9.6 29.0 12.7 15.1 9.9 13.3 19.1 39.2 19.8 19.8 16.9 18.9 57.5 20.3 18.7 24.4 21.4 23.3 15.3 40.9 19.4 15.5 24.7 15.3 41.5 41.8 29.8 25.7 41.6 47.9 28.5 31.3 28.2 32.5 19.9 16.6 43.5 40.0 63.5 17.3 27.7 32.4 50.6 35.6 26.3 40.7 41.0 19.6 30.6 59.5 52.1 29.3 19.9 87.5 27.8 20.7 16.3 20.1 22.6 72.2 30.1 17.0 34.6 32.8 10.0 22.3 16.2 27.8 37.4 19.8 56.1 40.6 21.9 49.5 16.6 12.0 15.6 10.7 7.8 24.0 14.0 15.0 13.2 12.1 25.7 22.0 16.8 11.5 6.9 21.8 24.8 10.5 16.3 11.6 12.3 12.9 12.8 16.4 12.4 14.4 13.0 13.8 13.0 12.5 12.7 13.3 6.7 16.0 8.6 2.9 10.6 9.4 14.5 17.9 13.1 7.9 13.3 11.4 24.5 11.5 8.8 9.2 0.0 21.6 3.5 12.2 84.1 18.8 2.6 6.7 8.3 9.0 4.9 20.8 3.2 13.4 22.3 8.9 5.6 5.4 10.8 7.6 3.9 20.4 21.0 5.0 3.8 13.3 16.2 10.0 6.6 5.3 11.5 9.7 8.8 1.9 11.4 9.9 15.5 2.5 3.5 13.1 10.0 10.1 13.2 25.3 22.4 62.2 5.9 7.2 6.6 9.9 11.8 24.7 40.4 20.8 11.8 13.0 7.3 12.0 17.9 11.6 CHMP2A "BC-2, CHMP2, VPS2, VPS2A" ENSG00000130724 "Charged multivesicular body protein 2A" O43633 19 58551566-58555105 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041153, HPA042031" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 230000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA041153: AB_10964358, HPA042031: AB_10961727" "unprognostic (1.80e-1)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (2.54e-1)" "unprognostic (3.86e-2)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.98e-1)" "unprognostic (2.21e-1)" "unprognostic (3.09e-2)" "unprognostic (4.23e-2)" "unprognostic (2.71e-2)" 131.8 185.9 144.9 86.8 149.6 162.3 125.1 153.7 171.9 108.9 143.5 141.3 113.4 111.7 150.1 154.9 104.6 83.1 182.6 144.4 147.8 163.3 161.3 116.9 81.9 151.1 147.0 101.9 125.0 147.8 118.7 95.8 151.3 112.5 124.1 75.2 137.2 97.1 222.9 158.4 121.9 83.6 149.0 121.2 143.8 73.9 146.8 82.6 123.2 151.7 95.1 114.3 113.7 157.4 110.4 290.9 91.4 85.0 138.9 172.9 112.9 100.0 204.3 52.0 56.0 86.3 160.1 29.3 143.2 168.1 149.2 87.7 76.1 190.4 43.7 98.8 628.2 71.8 214.0 134.7 266.6 121.1 108.0 201.5 266.0 81.5 257.8 175.3 153.1 135.5 86.8 135.6 159.5 187.1 153.7 111.3 38.3 304.2 220.3 65.2 78.6 222.0 230.1 246.8 107.3 181.2 162.0 213.7 123.4 57.3 164.3 121.5 174.4 262.0 37.7 77.2 117.3 339.0 404.9 95.2 185.0 141.0 176.6 278.9 247.4 351.1 134.9 232.7 114.5 127.0 148.0 153.1 216.2 123.0 102.0 116.3 820.6 131.6 243.9 197.1 215.5 208.4 144.9 149.6 153.7 171.9 144.4 147.8 151.1 147.0 151.3 149.0 146.8 157.4 166.1 99.3 119.8 9.4 72.9 165.6 261.4 287.7 69.4 73.9 124.7 120.6 118.7 154.4 207.2 165.5 16.7 288.8 76.5 555.2 442.2 332.6 121.9 194.0 109.2 143.6 155.4 142.5 5.3 522.5 296.8 113.5 115.7 198.8 121.5 102.1 142.5 214.0 269.1 52.2 5.6 296.6 217.7 142.0 145.8 90.9 145.1 134.5 215.3 6.5 203.6 217.6 147.2 3.0 13.4 479.8 615.3 133.2 77.3 258.5 607.0 599.8 242.1 94.3 85.5 103.9 169.7 116.8 89.7 109.5 198.5 460.0 89.2 149.3 226.3 372.7 CIAO1 "CIA1, WDR39" ENSG00000144021 "Cytosolic iron-sulfur assembly component 1" O76071 2 96266159-96274173 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017882 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA017882: AB_1846738" "unprognostic (2.34e-1)" "unprognostic (4.68e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (4.13e-5)" "unprognostic (1.55e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (9.86e-2)" "unprognostic (5.16e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (5.23e-3)" "unprognostic (8.72e-2)" "unprognostic (2.33e-1)" "unprognostic (5.26e-2)" "unprognostic (2.15e-2)" 18.4 32.4 26.8 17.0 28.3 12.1 19.4 30.2 29.7 18.9 26.3 16.8 20.1 14.8 18.0 20.1 19.7 15.1 30.4 27.8 27.8 31.0 32.8 17.6 22.3 27.7 27.6 18.6 17.9 36.2 13.4 18.7 28.3 16.9 17.6 17.4 23.6 19.5 27.8 19.3 17.6 16.5 28.9 21.3 16.7 17.1 28.6 22.2 20.5 28.0 21.3 18.6 13.9 30.2 31.8 27.2 28.8 32.3 49.8 40.9 32.0 27.1 31.9 37.5 39.8 44.1 23.0 44.6 46.6 29.8 42.0 28.0 40.8 29.7 33.4 25.0 58.0 28.9 19.4 47.4 28.8 37.8 32.2 35.1 34.5 28.5 43.2 35.9 39.9 33.8 36.9 29.8 35.9 38.1 42.2 40.8 51.3 44.5 58.0 38.3 33.2 47.3 42.6 31.6 36.0 42.2 19.9 48.0 53.1 40.1 24.8 41.4 30.4 26.2 35.4 36.7 29.3 43.5 49.6 30.1 38.4 37.9 31.4 30.9 27.7 34.2 27.8 23.8 31.9 20.9 25.8 29.8 29.1 24.9 24.3 28.5 23.6 30.0 33.8 18.8 23.5 33.0 26.8 28.3 30.2 29.7 27.8 27.8 27.7 27.6 28.3 28.9 28.6 30.2 33.3 28.9 31.4 26.8 32.4 29.1 28.7 39.0 35.9 24.3 23.2 28.4 27.0 15.7 31.6 14.7 14.6 59.3 42.5 21.8 39.2 40.0 25.0 21.2 30.7 30.1 15.7 32.4 44.5 33.6 60.1 32.6 28.1 21.2 37.2 33.3 19.2 27.4 45.2 26.9 36.6 21.1 44.7 23.4 29.6 25.8 20.2 30.6 19.6 20.6 40.6 19.0 42.2 25.1 25.2 35.5 13.0 16.6 44.8 51.7 43.6 72.7 36.2 24.0 32.9 27.3 34.4 42.5 42.3 43.5 34.5 49.8 38.6 54.5 23.6 43.0 CIAO2B "CGI-128, CIA2B, FAM96B, MIP18" ENSG00000166595 "Cytosolic iron-sulfur assembly component 2B" Q9Y3D0 16 66932065-66934423 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 143.6;Cytotrophoblasts: 204.8;Extravillous trophoblasts: 190.4;Hofbauer cells: 201.5;Syncytiotrophoblasts: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041501, HPA041736" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA041501: AB_10795123, HPA041736: AB_10793932" "unprognostic (2.49e-1)" "unprognostic (3.79e-2)" "unprognostic (8.06e-2)" "unprognostic (5.42e-3)" "unprognostic (3.93e-2)" "unprognostic (4.91e-2)" "unprognostic (4.98e-2)" "unprognostic (8.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.83e-2)" "unprognostic (1.18e-1)" "unprognostic (8.96e-2)" "unprognostic (5.10e-2)" "unprognostic (1.50e-1)" "unprognostic (9.84e-2)" "unprognostic (6.48e-2)" "unprognostic (1.12e-2)" 92.2 131.3 151.9 59.2 162.7 49.1 78.5 168.2 176.4 89.4 148.5 94.0 63.3 76.8 62.5 156.3 84.2 57.8 215.0 152.9 158.5 158.4 152.9 92.4 83.6 159.3 156.5 90.1 69.9 115.1 112.3 66.0 159.1 80.5 59.8 32.7 69.5 48.8 347.5 60.8 80.3 52.8 160.6 81.8 82.9 76.9 156.7 69.9 87.0 119.6 63.3 86.5 82.6 169.1 131.6 291.8 96.8 122.1 119.9 112.7 118.2 117.3 130.7 175.7 219.5 309.5 147.8 118.4 148.6 139.4 151.1 169.7 140.0 141.7 125.1 148.9 198.1 72.3 83.6 368.3 227.1 107.8 275.1 112.2 135.5 208.4 180.8 133.2 120.8 206.9 124.1 76.7 144.9 252.6 184.6 258.8 129.7 112.5 351.2 155.5 103.3 228.6 264.9 117.0 170.0 190.0 251.4 67.2 186.4 74.4 74.5 176.7 103.6 130.9 156.2 74.5 165.9 167.0 146.7 311.7 231.9 111.3 174.4 209.5 190.1 202.2 169.9 222.3 167.9 226.6 180.2 186.1 216.7 189.7 142.8 159.1 94.9 185.8 241.3 389.8 270.1 207.5 151.9 162.7 168.2 176.4 152.9 158.5 159.3 156.5 159.1 160.6 156.7 169.1 56.8 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.6 0.0 0.0 0.0 0.0 204.8 53.1 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 190.4 38.9 0.0 0.0 0.0 0.0 0.0 0.0 201.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 0.0 248.6 10.9 0.0 0.0 0.0 CINP MGC849 ENSG00000100865 "Cyclin dependent kinase 2 interacting protein" Q9BW66 14 102341102-102362916 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.47e-1)" "unprognostic (2.84e-1)" "unprognostic (1.50e-2)" "unprognostic (8.07e-2)" "unprognostic (2.19e-1)" "unprognostic (2.17e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (3.91e-2)" "unprognostic (2.61e-2)" "unprognostic (3.41e-2)" "unprognostic (2.55e-1)" "unprognostic (1.46e-3)" "unprognostic (1.85e-1)" "unprognostic (1.46e-1)" "unprognostic (2.40e-1)" "unprognostic (2.71e-1)" 20.9 23.9 27.4 13.3 30.5 28.8 19.8 31.1 32.2 14.3 23.1 18.0 13.6 11.5 21.9 25.2 14.3 15.0 27.8 25.7 28.4 22.6 33.5 15.7 20.3 30.0 28.7 13.7 44.1 19.3 12.6 15.0 30.0 15.9 15.9 4.5 29.8 13.7 31.9 16.9 15.1 17.1 30.3 17.1 23.6 29.2 28.7 19.5 18.3 27.0 17.8 18.2 14.4 33.3 32.1 75.1 29.1 33.3 54.5 71.6 33.4 47.0 61.1 63.3 52.3 50.8 49.6 36.3 45.8 59.4 31.6 52.7 52.0 64.7 57.6 41.6 40.2 26.2 48.0 60.4 46.7 67.2 25.7 54.7 47.5 46.1 52.6 41.9 67.7 34.2 38.5 44.0 57.9 161.2 39.8 36.4 31.2 90.2 74.5 26.2 41.3 47.8 61.5 73.2 30.9 30.2 36.6 60.0 33.6 25.7 71.3 31.5 47.3 36.1 22.0 108.7 42.1 84.9 70.9 63.3 60.4 42.5 41.9 46.1 58.3 55.0 37.5 58.4 34.4 44.1 33.4 35.1 54.3 37.6 31.9 31.5 49.8 38.0 50.8 50.7 41.6 46.4 27.4 30.5 31.1 32.2 25.7 28.4 30.0 28.7 30.0 30.3 28.7 33.3 27.5 28.9 16.2 3.3 19.1 14.0 26.0 37.5 14.2 18.2 25.2 28.1 39.7 15.7 29.0 20.2 12.5 48.5 18.4 19.1 56.7 39.6 59.4 15.4 24.9 28.8 19.7 29.5 4.1 45.2 53.7 27.8 16.3 16.7 19.6 25.8 28.5 43.9 59.8 15.2 3.6 27.1 18.3 25.5 22.2 111.2 29.8 28.1 17.8 0.0 65.8 25.2 35.0 4.0 10.0 42.6 21.9 20.3 36.5 25.9 43.9 82.2 19.8 20.1 32.9 18.0 21.4 90.1 16.1 33.6 15.8 37.1 20.5 33.9 32.9 25.4 CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361531-6370242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria NA NA 8500 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA010649: AB_1078538" "unprognostic (2.28e-1)" "unprognostic (7.14e-2)" "unprognostic (2.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (6.17e-3)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "prognostic favorable (6.50e-4)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (6.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.86e-3)" 48.6 65.8 52.0 41.5 51.5 42.9 45.1 52.2 63.8 39.1 58.0 46.6 47.4 41.1 17.8 56.1 40.1 20.8 78.0 50.9 52.7 60.5 90.7 39.7 47.7 52.8 52.4 38.5 53.6 36.6 44.5 25.4 49.5 41.0 22.9 15.6 48.3 31.2 146.8 47.5 43.6 25.1 51.8 45.6 55.6 45.2 54.5 45.2 36.1 59.3 35.6 44.6 37.9 53.9 146.7 98.2 61.2 113.9 38.7 54.8 62.4 76.9 59.5 112.2 102.5 87.2 48.9 124.1 122.8 61.3 61.1 83.1 63.5 109.1 38.5 133.8 189.3 95.8 82.2 122.9 106.6 90.7 129.8 73.4 74.4 78.9 82.9 69.7 113.9 188.5 97.5 174.5 72.3 192.8 153.1 104.5 93.2 100.6 207.8 108.6 73.2 206.2 81.2 79.4 99.3 95.9 48.9 123.8 133.0 36.7 67.3 130.6 76.9 70.5 69.7 180.7 156.0 235.4 225.3 137.2 103.5 132.9 117.3 29.4 82.6 47.8 112.0 79.6 133.5 119.5 159.4 139.6 102.4 131.5 138.4 137.4 62.1 126.5 55.5 155.5 207.2 162.6 52.0 51.5 52.2 63.8 50.9 52.7 52.8 52.4 49.5 51.8 54.5 53.9 39.6 22.4 35.2 8.1 45.9 44.9 59.5 90.8 38.1 31.0 47.6 57.9 45.8 55.8 46.2 44.1 12.5 72.2 43.7 56.0 144.8 88.8 105.5 27.6 43.1 51.6 35.3 54.9 5.4 96.6 113.6 42.4 36.2 35.0 26.0 63.1 61.8 89.6 81.3 21.9 7.5 50.9 54.9 38.9 35.0 229.8 42.6 38.7 55.2 4.7 70.6 46.6 46.4 4.5 9.5 101.9 67.7 43.2 82.4 89.5 110.9 189.0 44.5 24.6 13.1 30.0 79.9 67.7 48.1 56.5 37.1 57.7 65.3 95.1 65.4 65.4 CMC2 "C16orf61, DC13, MGC45036" ENSG00000103121 "C-X9-C motif containing 2" Q9NRP2 16 80966448-81020270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006871, CAB026396" Approved Supported Mitochondria NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026396: , HPA006871: AB_1845581" "unprognostic (2.43e-1)" "unprognostic (3.63e-2)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "unprognostic (1.50e-1)" "unprognostic (3.01e-3)" "unprognostic (2.48e-2)" "unprognostic (6.36e-2)" "unprognostic (9.20e-2)" "unprognostic (3.84e-3)" "unprognostic (3.48e-2)" "unprognostic (4.57e-3)" "prognostic favorable (2.64e-5)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (2.68e-1)" 22.1 24.6 47.6 14.0 50.0 45.2 17.0 49.0 60.2 17.2 41.2 22.7 19.1 12.4 16.6 20.4 11.6 17.0 68.4 48.4 50.7 43.5 44.0 24.3 22.4 47.6 47.6 13.7 27.3 30.4 26.1 16.3 47.5 34.9 16.9 16.1 14.8 12.4 54.0 15.3 20.3 15.0 48.3 21.7 27.2 47.0 51.2 30.1 16.2 33.9 17.1 20.7 17.0 54.2 74.8 103.1 76.1 43.7 25.1 25.0 44.9 73.4 33.1 64.0 32.9 71.7 49.9 33.5 53.3 35.8 62.9 52.6 52.5 42.8 84.9 50.9 63.3 51.9 68.4 78.6 40.6 43.5 85.4 21.8 23.8 77.7 43.5 29.2 57.1 83.1 124.2 43.5 63.3 140.1 68.1 138.4 45.2 59.7 62.0 84.2 41.2 43.8 50.4 35.9 64.1 37.1 110.6 39.8 87.3 39.4 78.7 39.2 32.8 57.9 82.0 56.6 75.3 45.4 107.6 193.8 44.6 55.3 69.1 33.2 28.0 37.3 28.8 29.6 27.5 39.1 36.5 30.1 31.6 34.9 25.3 29.2 12.0 44.6 34.2 45.3 64.4 18.0 47.6 50.0 49.0 60.2 48.4 50.7 47.6 47.6 47.5 48.3 51.2 54.2 41.2 35.3 38.8 48.0 54.9 97.6 75.5 53.9 48.9 31.9 48.0 50.7 204.7 42.9 36.5 47.8 54.2 44.8 78.9 29.5 158.5 34.4 95.4 44.2 33.7 36.0 38.3 55.5 88.6 38.0 62.8 45.0 42.8 45.2 95.5 37.3 25.4 86.0 51.4 30.3 62.2 42.9 59.0 70.5 84.1 168.3 24.5 59.7 65.8 14.0 33.8 29.3 51.5 48.7 74.0 39.0 31.9 29.3 83.5 69.1 48.5 166.1 31.4 16.7 59.2 33.3 47.0 263.5 121.5 65.0 102.1 38.0 84.7 55.3 44.8 74.4 CMC4 "MTCP1, MTCP1NB, p8, P8MTCP1" ENSG00000182712 "C-X9-C motif containing 4" P56277 X 155061622-155071136 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 113.5" "Low region specificity" "Detected in all" HPA045866 Approved Supported Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA045866: AB_10964642" "unprognostic (4.54e-3)" "unprognostic (7.31e-2)" 14.5 11.5 15.1 9.3 17.0 8.2 12.2 17.5 17.7 13.3 14.8 17.0 12.5 12.4 16.7 11.2 11.8 10.6 52.6 14.3 16.6 15.1 23.3 8.4 15.0 18.0 16.5 15.2 32.7 12.7 11.8 8.2 17.0 12.8 7.0 7.3 18.9 12.6 31.8 10.8 10.1 7.9 16.6 9.7 11.8 8.0 16.0 6.8 14.1 24.5 8.4 12.4 11.6 17.9 63.7 16.6 9.5 19.8 24.5 23.6 14.2 12.0 17.5 16.7 28.3 10.2 11.1 40.7 30.8 13.9 48.0 20.5 11.8 16.2 10.8 45.5 30.7 6.2 10.2 13.5 25.2 12.8 9.3 22.8 24.9 16.7 20.2 15.9 13.3 25.3 6.2 15.2 17.1 23.5 17.2 23.8 5.6 25.3 42.5 14.6 20.9 28.5 18.3 4.2 19.0 14.4 16.0 17.9 20.3 10.9 13.3 8.1 17.3 26.1 16.9 16.4 16.8 62.9 67.3 113.5 23.7 29.5 16.9 2.0 12.9 22.2 14.8 7.5 15.3 19.1 11.9 14.3 19.6 18.6 3.5 9.5 1.2 23.1 3.0 3.8 15.1 8.3 15.1 17.0 17.5 17.7 14.3 16.6 18.0 16.5 17.0 16.6 16.0 17.9 3.9 0.0 4.1 3.3 1.9 0.8 1.1 2.6 2.8 1.0 3.4 5.0 0.0 1.5 6.0 0.0 0.0 1.0 3.9 0.9 3.9 1.5 0.1 2.4 2.7 1.8 1.8 7.8 1.6 0.5 1.0 2.8 2.0 1.4 5.1 2.5 2.2 4.7 1.0 0.0 2.3 0.8 0.0 1.3 2.6 1.4 3.7 1.9 1.8 1.9 1.0 1.4 2.1 2.5 4.6 0.7 1.2 1.9 4.0 0.5 2.0 4.1 4.8 0.3 0.0 1.2 2.0 1.4 0.8 4.2 2.4 1.2 2.9 1.2 1.6 0.7 COA1 "C7orf44, FLJ10803, MITRAC15" ENSG00000106603 "Cytochrome c oxidase assembly factor 1 homolog" Q9GZY4 7 43608456-43729717 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011944 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA011944: AB_1848671" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (2.22e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.21e-1)" "unprognostic (4.42e-2)" "unprognostic (2.22e-2)" "unprognostic (5.22e-2)" "unprognostic (6.74e-2)" "unprognostic (1.52e-1)" "unprognostic (3.52e-1)" "unprognostic (1.02e-2)" "unprognostic (2.56e-2)" "unprognostic (5.39e-2)" 17.1 17.1 20.8 17.2 21.2 23.8 16.0 22.0 25.9 7.7 22.3 12.7 12.9 9.4 14.3 17.0 10.5 12.3 59.2 20.6 21.9 28.3 16.6 13.6 31.5 20.8 20.9 6.9 28.4 25.7 6.4 12.9 21.4 8.5 16.3 23.5 16.4 8.4 74.5 5.6 11.8 10.4 21.0 15.5 17.2 10.9 21.1 27.2 16.5 78.2 35.2 16.3 8.2 21.5 35.4 93.4 75.6 75.2 21.8 24.4 50.7 47.5 82.7 64.5 66.7 71.9 78.8 67.0 79.7 29.9 135.8 50.4 88.9 74.7 81.1 60.4 81.3 83.5 48.8 67.3 35.9 65.7 35.6 20.2 47.1 47.0 69.1 69.0 59.8 79.3 144.1 56.4 52.7 48.6 97.2 164.2 47.9 73.4 66.8 58.2 69.5 125.0 80.3 39.2 46.5 83.0 48.6 89.1 32.5 108.7 66.9 43.6 44.9 31.7 69.2 31.5 69.7 133.7 117.8 122.9 90.4 82.4 86.4 2.0 23.6 21.3 18.7 27.7 13.4 31.8 17.1 18.9 27.6 33.0 23.4 30.2 32.8 30.3 24.1 24.4 18.7 23.3 20.8 21.2 22.0 25.9 20.6 21.9 20.8 20.9 21.4 21.0 21.1 21.5 30.0 28.9 38.8 52.9 52.1 13.0 65.3 41.2 38.1 46.1 39.9 43.6 59.0 30.0 34.4 35.0 45.9 33.7 42.9 14.0 117.4 55.3 7.3 39.0 27.8 33.8 27.6 84.4 76.1 42.9 47.9 27.6 29.0 28.6 26.0 40.9 20.7 26.7 58.6 33.7 88.1 22.3 54.9 38.0 19.6 9.6 29.5 32.0 37.4 70.3 45.5 37.3 57.7 100.5 71.7 41.0 15.9 19.5 51.3 59.4 39.8 124.7 30.9 56.3 13.1 35.0 27.4 97.4 85.7 48.9 16.8 17.9 47.1 40.4 26.9 55.2 COA4 "CHCHD8, CMC3, E2IG2" ENSG00000181924 "Cytochrome c oxidase assembly factor 4 homolog" Q9NYJ1 11 73872667-73876901 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040126 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA040126: AB_10795415" "unprognostic (7.30e-2)" "unprognostic (8.69e-2)" "unprognostic (2.09e-1)" "unprognostic (2.60e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.64e-3)" "unprognostic (1.49e-1)" "unprognostic (2.22e-2)" "prognostic favorable (3.87e-4)" "unprognostic (1.31e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (8.17e-2)" 45.1 96.2 46.9 36.8 52.5 25.4 39.0 51.6 52.0 37.1 46.2 44.5 49.0 35.8 32.5 48.0 40.2 40.3 63.1 46.0 49.4 70.4 99.7 31.3 47.3 51.0 50.4 37.8 46.5 49.6 34.2 37.6 51.0 45.1 42.2 15.7 42.7 36.2 72.2 33.1 49.6 32.4 50.6 37.1 41.6 31.6 50.3 32.3 55.7 55.9 36.0 54.6 37.4 56.9 106.4 201.9 80.2 119.0 70.6 86.6 79.3 107.4 75.5 126.0 107.2 147.4 132.5 91.3 214.7 90.2 99.9 105.7 124.2 146.1 98.3 120.6 115.1 156.3 118.1 141.8 130.5 107.2 115.0 109.4 136.1 207.0 136.6 70.9 120.0 87.0 135.3 87.5 118.3 210.8 83.7 168.1 104.3 422.7 205.9 96.2 174.3 244.0 137.5 101.3 72.5 121.3 99.0 110.7 295.3 78.8 162.3 108.0 83.8 102.8 91.7 212.9 142.8 103.3 125.1 313.1 57.0 132.0 121.4 18.5 49.6 12.7 35.9 52.2 47.0 58.1 42.0 37.8 61.1 48.5 44.6 48.2 3.4 43.1 51.4 80.2 47.7 38.6 46.9 52.5 51.6 52.0 46.0 49.4 51.0 50.4 51.0 50.6 50.3 56.9 48.9 35.3 36.0 6.8 48.6 53.5 75.7 89.7 47.8 19.5 64.3 86.1 66.7 85.8 55.5 55.2 22.9 168.8 36.7 97.8 129.1 89.2 37.3 77.2 90.9 49.7 72.6 68.3 3.6 94.9 111.3 54.2 69.3 72.0 62.1 83.9 33.2 184.1 97.5 18.5 5.8 98.6 28.5 44.8 34.2 13.3 55.0 44.7 28.4 2.8 55.2 67.5 49.4 8.5 18.8 98.2 85.1 38.4 47.3 139.5 174.2 266.2 47.1 18.5 6.6 81.6 51.0 78.7 34.2 86.3 51.3 122.3 39.9 150.7 121.2 98.7 COA6 C1orf31 ENSG00000168275 "Cytochrome c oxidase assembly factor 6" Q5JTJ3 1 234373456-234385080 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028588 Approved Supported Nucleoplasm,Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA028588: AB_10601123" "unprognostic (6.26e-2)" "unprognostic (1.92e-1)" "unprognostic (3.05e-1)" "unprognostic (1.01e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (4.04e-3)" "unprognostic (4.89e-2)" "unprognostic (2.79e-2)" "unprognostic (6.25e-3)" "unprognostic (9.24e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (2.38e-1)" "unprognostic (5.24e-2)" "unprognostic (2.19e-1)" "prognostic favorable (7.12e-4)" 23.5 34.2 38.2 21.6 44.0 17.1 21.1 35.7 45.1 15.2 37.0 30.4 44.8 15.1 32.2 31.9 15.3 16.2 41.0 39.7 36.4 44.8 36.7 15.3 30.9 35.5 35.9 15.9 25.8 26.4 16.4 14.2 37.6 22.6 25.6 16.3 24.3 13.2 101.4 16.1 31.2 14.0 36.2 21.2 27.7 9.0 36.2 25.8 17.2 60.9 21.2 21.8 19.4 39.1 69.6 87.2 31.0 35.2 31.7 62.3 98.2 49.9 29.7 51.0 47.8 67.6 90.2 68.4 90.0 28.6 95.7 86.6 48.6 61.4 40.5 86.0 207.1 30.9 92.8 181.4 121.9 77.0 57.6 41.4 80.8 67.2 51.6 44.5 63.9 75.0 153.4 60.2 56.2 37.1 73.7 148.0 76.2 155.5 41.0 43.0 37.1 135.6 65.0 64.6 55.0 39.9 48.5 84.7 162.1 19.7 75.2 130.0 48.9 60.2 50.2 81.7 151.7 71.2 149.8 86.0 46.2 120.3 110.3 59.4 70.3 23.2 40.0 68.2 39.0 65.4 63.3 49.7 76.3 43.4 65.0 49.2 18.8 44.9 59.0 52.2 85.9 48.6 38.2 44.0 35.7 45.1 39.7 36.4 35.5 35.9 37.6 36.2 36.2 39.1 31.2 9.6 24.0 5.9 29.6 57.2 50.2 80.7 34.1 13.6 35.6 57.0 88.1 30.0 51.1 47.8 4.2 50.8 21.1 61.4 103.7 55.2 4.2 63.3 32.9 27.8 22.2 33.7 19.0 69.4 79.2 31.0 31.1 40.9 22.2 35.4 26.7 52.4 84.3 11.8 13.6 64.2 52.9 37.7 32.3 4.9 26.1 39.6 30.2 5.6 45.5 28.1 28.8 9.0 5.9 62.7 42.0 28.2 24.3 77.0 83.4 131.3 64.0 17.8 19.7 22.8 31.9 23.7 26.9 57.9 58.7 43.6 30.6 63.5 72.4 81.8 COG8 "DOR1, FLJ22315" ENSG00000213380 "Component of oligomeric golgi complex 8" Q96MW5 16 69320140-69339583 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041406, HPA049429" Approved Supported "Golgi apparatus" No No "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA041406: AB_2677459, HPA049429: AB_2680763" "unprognostic (4.02e-2)" "unprognostic (6.46e-2)" "unprognostic (2.90e-1)" "unprognostic (1.19e-2)" "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (4.35e-2)" "unprognostic (1.11e-1)" "unprognostic (2.02e-1)" "prognostic favorable (3.12e-5)" "unprognostic (3.10e-1)" "prognostic favorable (2.47e-7)" "unprognostic (4.73e-2)" "unprognostic (2.58e-1)" "unprognostic (7.83e-2)" "unprognostic (1.35e-2)" 9.9 14.5 19.7 8.5 23.2 6.5 11.1 23.2 24.4 9.8 24.0 10.5 10.5 10.8 14.1 9.9 13.9 7.7 11.2 19.4 19.7 13.4 15.0 10.2 11.3 21.1 20.6 13.7 14.2 19.9 12.0 7.9 21.2 10.3 9.9 7.7 13.8 10.6 18.1 16.3 10.0 10.5 20.3 10.9 11.2 20.3 20.9 12.2 13.0 15.8 11.3 9.4 7.7 28.1 13.2 28.5 18.2 26.7 30.1 21.0 19.4 16.9 18.6 23.0 18.7 26.2 19.8 23.7 18.1 23.0 12.4 24.9 29.5 24.3 19.8 11.9 26.4 17.0 19.9 35.0 21.3 21.1 14.8 25.2 23.5 25.2 14.7 22.2 22.6 20.4 35.4 5.7 16.7 38.3 19.4 31.3 32.2 17.8 20.5 35.6 12.6 33.3 23.6 11.1 26.0 31.1 37.5 15.0 17.5 18.4 35.4 17.8 20.5 16.8 14.4 15.8 14.1 31.3 27.1 36.8 17.3 18.8 19.2 41.4 19.6 20.6 17.8 19.0 19.6 13.3 19.2 18.2 18.6 19.0 17.4 16.7 15.6 22.2 17.6 10.7 19.6 16.8 19.7 23.2 23.2 24.4 19.4 19.7 21.1 20.6 21.2 20.3 20.9 28.1 3.2 9.6 9.7 1.3 9.4 4.2 10.4 5.8 5.2 18.9 7.3 6.7 0.0 24.3 10.6 11.0 18.8 15.0 5.0 12.6 1.9 7.6 17.4 6.1 6.4 7.2 12.7 5.5 1.9 8.0 9.1 7.4 7.1 4.6 7.0 9.0 15.7 28.5 9.5 11.8 2.0 11.7 20.3 7.9 3.3 4.8 12.8 3.1 5.4 1.0 8.4 12.1 10.3 2.0 2.6 5.4 9.5 15.8 9.0 9.6 19.3 15.3 10.2 19.9 13.1 15.5 6.2 9.9 13.6 7.2 4.1 9.2 8.3 5.4 16.7 7.2 COLQ EAD ENSG00000206561 "Collagen like tail subunit of asymmetric acetylcholinesterase" Q9Y215 3 15450133-15521751 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Neurotransmitter degradation" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 17.3;Excitatory neurons: 45.1;Inhibitory neurons: 46.3;Late spermatids: 16.6;NK-cells: 15.5;Oligodendrocyte precursor cells: 18.1;Oligodendrocytes: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 60.9" "Lineage enriched" "Detected in many" 34 "T-cells: 60.9" "Group enriched" "Detected in some" 6 "BEWO: 11.5;HDLM-2: 3.8;U-937: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045876 Approved "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA045876: AB_2679479" "unprognostic (4.08e-3)" "unprognostic (2.61e-2)" "unprognostic (2.13e-3)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (4.62e-2)" "unprognostic (1.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (1.28e-3)" "unprognostic (4.68e-1)" "unprognostic (7.00e-5)" "unprognostic (6.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-4)" 2.5 2.3 3.1 0.7 3.2 0.8 2.2 3.9 4.6 4.6 11.9 3.7 1.0 3.4 1.6 0.9 8.8 1.1 17.9 3.7 2.7 2.9 3.4 2.5 3.9 4.8 3.2 3.6 1.7 3.6 5.7 0.3 2.8 4.6 0.5 0.6 1.5 0.8 10.8 1.6 2.6 0.7 2.6 7.2 2.4 5.0 2.3 2.6 2.6 5.1 3.0 2.2 2.4 2.9 0.1 0.0 0.7 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 3.8 0.4 0.2 0.5 0.0 0.0 0.1 0.3 0.4 0.0 0.3 0.1 0.2 0.3 0.5 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.0 0.2 1.0 0.0 0.0 0.2 0.5 0.6 0.0 0.0 0.1 0.2 0.2 0.1 0.8 0.4 0.0 0.0 5.2 0.1 0.0 0.6 0.0 9.9 0.0 60.9 0.0 5.3 7.4 0.0 0.0 0.5 0.6 0.0 1.8 0.0 0.4 0.3 3.5 3.1 3.2 3.9 4.6 3.7 2.7 4.8 3.2 2.8 2.6 2.3 2.9 0.6 0.0 0.6 17.3 0.5 0.3 0.2 0.1 0.0 0.3 0.4 0.6 0.7 0.0 1.4 0.0 0.0 0.3 7.7 0.0 0.0 0.1 4.1 6.5 1.4 0.4 1.2 0.4 45.1 0.0 0.2 0.6 1.1 0.8 0.0 3.3 1.8 0.8 0.2 6.7 46.3 0.2 2.0 0.6 0.0 16.6 1.8 0.4 0.0 7.5 0.4 0.3 15.5 18.1 18.3 0.2 0.1 4.5 2.0 0.2 0.0 0.2 4.3 0.7 0.0 0.5 0.7 1.5 0.5 0.0 0.1 2.3 4.1 1.4 0.3 0.1 COMMD1 "C2orf5, MGC27155, MURR1" ENSG00000173163 "Copper metabolism domain containing 1" Q8N668 2 61888724-62147247 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034633, HPA049223" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA034633: AB_10601800, HPA049223: AB_2680680" "unprognostic (6.08e-2)" "unprognostic (2.34e-2)" "unprognostic (2.83e-1)" "unprognostic (1.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.22e-2)" "unprognostic (5.58e-2)" "unprognostic (1.07e-1)" "unprognostic (4.93e-1)" "unprognostic (3.41e-2)" "unprognostic (2.26e-1)" "unprognostic (2.07e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (1.27e-1)" "unprognostic (5.51e-2)" "unprognostic (2.77e-1)" 20.8 26.4 22.2 21.9 23.4 20.4 27.0 25.2 33.0 23.0 22.9 18.6 22.6 20.0 30.1 24.8 20.9 20.2 54.7 23.5 22.9 31.2 35.9 18.7 23.5 22.1 22.1 21.3 24.1 24.4 14.8 26.5 22.6 22.2 22.6 20.1 33.5 20.2 35.2 22.2 14.9 29.9 22.4 20.6 19.2 24.4 22.2 20.7 28.1 38.1 25.5 23.9 19.8 24.1 23.2 29.1 32.0 25.4 41.2 41.2 27.4 27.2 45.6 53.7 37.9 50.1 20.4 40.4 22.3 50.8 45.8 17.6 18.0 33.1 55.8 43.9 21.1 31.5 16.3 56.0 35.1 49.6 23.8 34.6 37.7 26.1 30.8 39.2 54.6 23.2 19.6 64.3 56.7 43.6 38.6 87.4 27.9 19.0 39.0 27.1 42.4 46.7 49.3 25.0 19.5 21.7 30.7 50.9 28.6 31.8 32.4 21.4 25.9 48.1 41.5 30.2 42.4 26.6 22.9 48.6 26.5 42.8 42.8 62.4 96.2 48.4 63.0 86.5 63.4 91.8 71.5 72.0 117.3 84.7 68.1 73.8 8.1 91.1 78.4 109.5 88.8 110.8 22.2 23.4 25.2 33.0 23.5 22.9 22.1 22.1 22.6 22.4 22.2 24.1 53.0 35.3 33.8 56.8 38.2 54.4 73.8 98.7 47.8 35.4 47.0 72.4 176.7 41.5 57.3 35.0 10.4 127.3 37.3 27.4 129.1 71.5 195.6 50.6 52.1 53.2 21.6 43.1 91.9 65.1 75.5 67.6 32.1 47.2 57.7 60.4 52.5 72.4 101.7 28.6 78.4 29.8 63.1 36.0 81.3 163.5 41.3 46.3 83.6 71.2 118.6 45.3 30.9 89.5 109.7 57.1 37.1 49.7 71.5 48.9 49.0 192.3 49.1 33.2 32.9 57.6 97.2 124.5 58.7 49.6 61.7 147.2 38.6 81.6 30.1 64.0 COPS5 "CSN5, JAB1, MOV-34, SGN5" ENSG00000121022 "COP9 signalosome subunit 5" Q92905 8 67043079-67083783 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 347.5;Late spermatids: 427.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004242, HPA004845, HPA051531" Supported Enhanced Nucleoplasm NA NA 37000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004242: AB_627835, HPA004845: AB_1078557, HPA051531: AB_2681522" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-3)" "unprognostic (2.53e-1)" "unprognostic (4.16e-2)" "unprognostic (2.04e-3)" "unprognostic (1.39e-1)" "unprognostic (2.15e-2)" "unprognostic (4.48e-2)" "unprognostic (4.74e-3)" "unprognostic (1.96e-2)" "unprognostic (1.90e-3)" "unprognostic (2.88e-2)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-2)" 43.5 43.8 52.1 33.3 54.2 39.4 45.2 58.3 62.6 34.2 52.0 45.5 45.6 34.0 43.6 42.2 35.6 31.6 100.0 53.2 57.1 56.3 71.0 33.1 40.9 55.1 53.3 33.4 43.0 58.5 31.1 50.9 56.8 36.4 51.6 39.7 42.3 36.6 125.2 36.0 47.8 47.6 57.4 33.4 37.6 58.7 56.2 52.6 37.8 134.9 48.7 42.2 30.0 59.7 104.0 97.8 79.6 74.4 83.1 88.3 63.3 89.0 74.0 121.2 108.9 62.6 125.4 96.5 39.9 93.6 86.8 84.1 109.2 98.9 134.0 92.4 92.1 135.9 95.2 87.3 82.2 86.3 79.1 81.0 126.2 99.1 132.6 95.2 121.2 100.3 163.0 64.6 111.8 96.5 154.3 157.6 107.1 217.2 108.6 97.2 56.7 76.4 131.3 91.6 48.6 66.7 51.0 98.4 91.6 71.2 160.9 90.8 89.9 60.1 74.9 74.7 70.3 81.4 108.5 127.7 89.1 97.6 84.1 65.8 52.0 64.5 35.8 55.7 37.2 36.8 34.6 39.9 63.9 33.7 36.1 32.4 38.3 51.9 56.6 34.0 53.2 43.8 52.1 54.2 58.3 62.6 53.2 57.1 55.1 53.3 56.8 57.4 56.2 59.7 55.0 22.4 26.0 19.2 40.6 49.3 45.1 102.6 28.5 36.4 43.7 51.8 119.9 58.6 61.2 31.3 33.3 143.8 58.0 38.1 88.0 73.4 347.5 44.6 38.2 46.4 34.2 69.2 21.5 60.0 101.4 45.2 25.5 37.1 36.1 50.9 34.2 35.5 79.3 25.2 21.5 41.5 59.0 31.7 28.5 427.2 43.2 40.2 28.4 10.3 59.9 62.0 56.7 18.6 32.4 50.1 48.6 51.1 46.6 54.0 87.8 81.9 46.1 53.0 32.9 49.1 87.8 123.4 49.6 42.9 47.5 127.8 42.3 72.5 55.4 50.6 COPS7A CSN7A ENSG00000111652 "COP9 signalosome subunit 7A" Q9UBW8 12 6724014-6731875 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026915 Supported Supported Nucleoplasm,Cytosol NA NA 54000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA026915: AB_1847156" "unprognostic (3.50e-1)" "unprognostic (1.33e-2)" "unprognostic (3.95e-3)" "unprognostic (3.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.96e-3)" "unprognostic (3.91e-2)" "unprognostic (4.26e-2)" "unprognostic (1.76e-1)" "unprognostic (8.24e-3)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" 45.0 52.8 69.2 32.9 69.1 19.7 36.1 69.7 71.7 34.1 66.0 44.5 29.9 39.2 46.7 55.2 44.7 32.7 79.1 71.9 70.9 48.3 53.3 34.7 29.9 72.0 72.0 34.8 40.3 71.9 51.1 42.7 71.4 42.8 30.1 46.8 44.5 40.2 103.6 39.2 29.0 43.1 67.3 33.3 41.2 24.0 77.1 22.8 45.8 98.1 30.4 45.8 38.5 67.4 73.3 78.8 34.0 33.3 96.3 114.0 84.9 93.2 107.8 87.6 86.7 54.3 95.0 47.1 37.1 111.2 49.9 55.9 45.7 86.6 75.5 70.3 57.8 47.0 50.1 63.9 84.6 47.1 28.3 106.7 80.6 97.5 183.4 100.1 61.8 29.2 33.3 18.1 116.0 58.7 29.5 30.3 92.9 91.4 64.1 18.8 71.9 47.2 69.0 69.0 19.4 47.2 58.4 67.5 97.2 79.5 29.9 68.0 70.1 90.8 48.4 82.3 85.6 21.0 24.7 38.4 150.6 60.0 104.7 85.9 56.4 86.1 36.3 73.2 35.8 26.2 30.7 32.2 65.3 36.0 30.2 29.8 43.7 31.0 58.9 41.3 30.9 49.9 69.2 69.1 69.7 71.7 71.9 70.9 72.0 72.0 71.4 67.3 77.1 67.4 23.7 16.0 17.5 17.0 14.7 13.9 31.4 39.8 25.0 37.0 29.1 27.6 36.7 22.8 28.0 23.9 6.2 72.6 11.7 15.7 66.5 47.8 4.3 21.4 28.0 23.4 12.6 17.0 13.0 49.7 58.2 34.8 13.7 22.9 16.5 13.0 22.9 26.3 63.2 30.3 15.3 18.6 69.2 24.2 14.4 6.5 23.0 26.1 12.4 5.6 50.0 51.4 13.4 11.1 11.9 49.8 18.6 25.6 16.2 34.3 22.3 47.3 23.8 23.8 39.5 21.7 33.2 16.9 40.6 39.2 13.9 59.1 12.6 40.6 17.1 30.7 COQ3 bA9819.1 ENSG00000132423 "Coenzyme Q3, methyltransferase" Q9NZJ6 6 99369401-99394195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 51.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.8;Distal tubular cells: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031273, HPA031274" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Mitochondria "HPA031273: AB_10611107, HPA031274: AB_10602176" "unprognostic (1.81e-2)" "unprognostic (2.69e-2)" "unprognostic (1.45e-2)" "unprognostic (4.62e-2)" "unprognostic (2.41e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.40e-1)" "unprognostic (8.77e-2)" "unprognostic (9.78e-2)" "unprognostic (1.09e-1)" "prognostic favorable (6.86e-5)" "unprognostic (4.61e-2)" "unprognostic (1.81e-1)" "unprognostic (5.45e-2)" "unprognostic (1.08e-1)" 6.4 10.1 13.4 5.2 14.3 4.6 8.6 14.7 18.0 5.6 13.7 10.7 8.2 5.2 7.6 9.3 5.1 3.5 30.9 13.8 13.9 12.7 15.1 3.5 5.6 13.8 14.0 6.8 6.6 14.2 8.5 3.0 13.9 7.7 12.5 11.9 9.6 8.4 37.3 6.9 6.6 6.3 13.7 6.4 7.4 3.0 13.8 7.9 5.2 51.1 7.1 6.8 6.5 13.7 20.2 11.4 13.5 19.2 8.6 9.6 18.4 17.0 10.5 25.2 29.0 15.9 8.5 19.6 11.1 12.8 16.3 18.3 22.7 26.6 30.6 21.0 29.1 24.1 15.5 17.1 11.3 35.0 9.0 6.1 16.0 14.9 14.9 5.5 15.6 23.8 37.2 14.5 13.6 19.8 15.5 29.0 16.4 19.7 21.7 7.5 13.8 26.1 19.9 17.3 21.0 11.2 11.8 18.0 22.9 9.0 22.1 22.8 5.6 10.9 16.0 17.0 26.4 5.1 10.0 30.9 14.0 33.6 16.4 14.1 2.9 2.4 5.0 6.9 5.8 5.6 6.4 8.1 7.3 2.5 10.5 7.8 0.4 10.1 6.1 4.9 5.2 4.7 13.4 14.3 14.7 18.0 13.8 13.9 13.8 14.0 13.9 13.7 13.8 13.7 4.7 3.2 3.7 6.5 3.9 4.5 6.8 26.1 7.4 8.1 5.0 6.3 42.8 5.7 11.2 3.7 0.0 14.0 2.2 3.7 33.2 11.5 0.5 3.5 4.9 5.5 0.0 8.2 10.6 10.5 13.3 5.9 3.6 2.6 1.3 6.6 3.3 8.6 6.8 6.7 13.2 7.3 24.4 1.3 3.5 0.3 8.1 2.4 5.4 1.0 2.0 13.2 4.1 4.5 7.6 9.2 5.8 6.0 4.7 2.4 5.2 12.0 4.9 8.7 6.6 6.5 10.6 3.6 10.9 8.0 4.3 6.3 3.7 11.1 9.8 4.7 COX14 "C12orf62, MGC14288" ENSG00000178449 "Cytochrome c oxidase assembly factor COX14" Q96I36 12 50112082-50120457 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 835.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044618, HPA062014" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044618: AB_10960419, HPA062014: AB_2684657" "unprognostic (5.71e-2)" "unprognostic (1.86e-2)" "unprognostic (1.43e-1)" "unprognostic (4.04e-1)" "unprognostic (1.87e-2)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (4.20e-3)" "prognostic unfavorable (7.90e-4)" "unprognostic (7.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.09e-3)" "unprognostic (3.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-3)" 124.0 106.4 96.3 47.1 101.4 66.2 105.6 110.3 129.7 63.6 120.1 92.4 83.4 46.2 130.5 68.5 54.9 62.9 238.6 94.5 105.5 143.8 145.4 62.3 74.5 102.6 99.8 52.8 62.0 127.8 88.0 54.7 102.9 67.0 77.5 60.6 84.9 80.7 247.6 49.8 84.0 58.7 102.9 66.9 76.5 32.6 104.0 54.9 87.3 276.7 62.0 74.2 47.3 110.2 78.4 168.3 32.8 79.4 169.4 105.7 60.5 61.1 92.7 98.8 89.5 156.7 109.1 69.9 171.9 78.3 82.6 79.0 57.2 87.5 91.7 78.7 236.6 154.3 140.4 139.2 65.1 112.1 133.7 123.8 129.9 67.1 76.7 100.5 96.2 83.1 70.2 153.4 109.1 193.3 93.7 170.3 51.5 116.4 211.3 77.6 52.4 176.8 155.0 149.1 91.0 51.4 92.4 177.5 195.6 72.6 115.1 103.6 75.2 55.0 58.1 92.3 50.1 106.3 199.0 93.5 77.9 105.0 30.9 258.8 197.8 172.7 146.1 194.5 155.6 213.7 186.9 167.0 190.0 188.0 176.7 173.7 67.0 153.1 178.2 247.2 224.8 214.8 96.3 101.4 110.3 129.7 94.5 105.5 102.6 99.8 102.9 102.9 104.0 110.2 91.5 60.9 120.6 11.1 108.8 124.9 91.2 212.9 87.0 68.2 169.2 192.5 524.4 161.5 138.7 222.5 22.9 191.9 111.1 320.9 565.4 131.4 7.1 117.5 58.7 99.2 156.0 69.2 13.1 170.1 122.6 90.3 81.6 88.1 65.4 64.0 88.9 397.9 219.6 47.1 16.3 214.7 187.2 152.3 110.4 22.9 129.2 117.7 149.4 6.5 181.2 111.0 111.2 7.1 22.3 116.8 262.4 109.4 93.0 129.5 492.6 835.5 157.5 67.4 105.2 51.5 130.8 51.1 56.0 121.6 159.3 127.5 112.2 115.4 227.4 118.6 COX17 ENSG00000138495 "Cytochrome c oxidase copper chaperone COX17" Q14061 3 119654513-119677454 "Cancer-related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042226, HPA048158" Supported Supported Mitochondria NA NA 220000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA042226: AB_2677911, HPA048158: AB_2680292" "unprognostic (1.98e-2)" "unprognostic (3.49e-2)" "unprognostic (1.96e-2)" "unprognostic (8.29e-2)" "unprognostic (2.88e-2)" "unprognostic (6.63e-3)" "unprognostic (3.49e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-1)" "unprognostic (7.11e-3)" "unprognostic (2.12e-1)" "unprognostic (4.45e-2)" "unprognostic (1.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.65e-1)" "unprognostic (9.19e-2)" "unprognostic (2.64e-2)" 81.6 178.5 106.5 77.1 111.2 113.3 68.8 117.5 122.4 50.3 149.2 90.2 90.2 41.2 114.1 55.9 47.3 59.4 279.9 105.5 123.6 94.7 172.7 62.3 110.4 115.8 115.3 31.5 102.0 412.1 119.2 63.9 115.7 78.6 78.7 120.6 80.8 90.7 401.4 43.3 88.5 62.9 112.5 64.9 107.5 44.4 113.0 106.6 94.4 363.9 89.8 75.9 35.7 118.6 219.6 257.0 122.7 33.3 53.4 53.1 45.7 130.5 84.2 127.3 133.4 226.4 157.7 164.6 158.0 72.1 174.8 84.0 138.5 154.9 74.9 205.5 155.9 145.0 195.3 180.1 63.1 205.0 246.7 56.6 142.7 77.9 106.0 82.2 87.9 200.8 122.4 370.7 155.4 410.2 212.8 283.5 133.8 212.2 413.3 88.3 82.3 273.7 203.2 141.0 210.5 86.4 153.1 137.1 189.7 76.9 180.5 313.0 66.6 91.3 144.9 59.8 168.4 257.5 348.9 361.1 129.0 157.8 164.2 591.4 241.1 630.6 218.1 357.5 208.1 378.3 241.7 230.3 252.8 320.4 189.1 187.0 174.4 213.6 487.3 538.7 352.6 260.1 106.5 111.2 117.5 122.4 105.5 123.6 115.8 115.3 115.7 112.5 113.0 118.6 194.5 157.0 167.1 5.2 161.5 94.1 132.8 267.9 46.7 108.9 153.8 147.2 622.8 238.8 202.4 498.4 43.8 137.4 116.7 385.3 716.1 264.0 115.0 282.4 64.3 164.7 214.2 162.9 3.8 413.7 193.9 99.3 150.3 178.8 309.3 70.2 116.0 779.8 216.1 75.7 5.6 327.8 427.2 181.8 281.2 39.9 91.0 190.8 277.5 11.2 345.7 178.8 137.0 8.5 8.8 459.7 512.8 136.9 176.5 198.2 434.6 786.2 280.2 174.4 184.1 112.9 171.6 286.0 159.2 85.4 125.4 211.0 129.0 49.6 151.1 199.0 COX20 "FAM36A, FLJ43269" ENSG00000203667 "Cytochrome c oxidase assembly factor COX20" Q5RI15 1 244835616-244845057 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 414.8;Proximal tubular cells: 464.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043617, HPA045490" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA043617: AB_10965694, HPA045490: AB_10962869" "unprognostic (5.84e-3)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (2.86e-1)" "unprognostic (3.62e-1)" "unprognostic (3.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.99e-1)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (2.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.02e-3)" 17.5 44.2 28.1 23.3 30.9 20.1 22.1 37.4 49.2 13.9 23.6 23.9 24.3 24.8 29.9 21.5 17.2 15.3 42.9 27.9 30.1 50.2 29.6 15.8 21.4 30.3 30.3 35.4 23.2 22.8 11.1 17.7 28.8 28.7 18.7 58.3 17.1 18.6 43.3 15.2 25.0 20.5 29.2 15.0 23.1 25.0 29.3 16.3 37.0 37.4 16.5 20.4 9.6 30.1 132.6 34.1 33.5 100.4 22.5 17.3 75.2 54.0 35.7 31.0 27.2 93.9 88.9 21.3 65.7 36.6 58.3 36.1 17.8 43.0 40.8 56.0 15.6 38.6 47.6 85.7 28.7 95.7 57.5 16.0 20.2 44.5 30.8 44.9 35.2 22.7 81.2 80.2 63.0 33.0 53.5 43.5 84.2 94.9 68.6 38.5 42.0 121.5 59.5 33.1 19.6 54.2 68.1 36.1 79.6 32.1 67.0 28.7 69.3 67.3 88.7 59.9 120.1 128.0 188.7 43.7 90.9 108.2 65.3 14.5 15.3 21.4 27.1 36.4 26.3 34.2 31.3 30.2 26.5 32.6 21.2 28.7 3.9 24.2 34.5 26.1 43.4 20.4 28.1 30.9 37.4 49.2 27.9 30.1 30.3 30.3 28.8 29.2 29.3 30.1 66.7 19.2 52.1 44.1 77.7 85.1 115.1 144.3 38.1 111.5 104.4 110.1 68.6 183.0 90.5 191.3 45.9 231.5 74.4 97.7 414.8 154.1 38.6 78.4 74.1 61.4 61.8 82.0 16.6 188.9 164.6 56.1 57.6 119.5 73.4 53.1 42.5 294.8 122.1 89.2 24.4 91.7 77.3 64.8 79.6 75.9 69.6 73.4 72.9 9.4 97.6 195.2 110.2 27.6 34.1 178.6 87.0 80.1 51.9 75.9 134.8 464.0 67.7 133.4 65.7 83.2 85.0 67.1 122.4 61.6 75.6 264.5 81.4 63.6 115.3 87.8 COX4I1 "COX4, COX4-1" ENSG00000131143 "Cytochrome c oxidase subunit 4I1" P13073 16 85798633-85807068 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002485, CAB004080" Supported Supported Mitochondria NA NA 55000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB004080: AB_2085427, HPA002485: AB_1078559" "unprognostic (4.73e-2)" "unprognostic (9.14e-3)" "unprognostic (2.65e-1)" "unprognostic (6.18e-3)" "unprognostic (2.47e-1)" "unprognostic (4.52e-2)" "unprognostic (2.65e-1)" "unprognostic (1.46e-1)" "unprognostic (5.97e-2)" "unprognostic (7.82e-3)" "unprognostic (3.32e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.56e-8)" "unprognostic (4.23e-2)" "unprognostic (4.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.38e-2)" 473.1 393.5 874.4 232.5 881.4 583.2 437.1 896.5 971.9 373.1 882.6 690.5 585.9 301.8 478.8 597.2 355.8 246.9 2047.0 869.5 909.5 632.7 611.2 318.6 412.8 896.4 891.1 366.2 490.4 900.7 362.1 256.7 908.6 377.1 707.7 261.2 421.2 312.3 1333.3 552.5 529.5 301.4 877.2 405.9 650.3 191.1 922.9 479.9 361.5 2063.3 538.7 422.6 420.9 881.0 433.7 677.7 460.2 616.8 823.6 761.2 785.7 379.6 771.2 702.3 346.7 1170.2 636.6 698.6 454.2 610.5 389.9 855.1 657.2 765.3 622.2 238.7 678.1 392.9 554.8 1093.8 741.9 362.9 282.0 893.1 1162.8 579.2 786.0 739.1 746.4 563.6 672.3 280.4 602.5 1510.6 730.9 1116.7 623.0 954.1 796.3 816.9 287.5 616.7 1066.7 840.2 543.2 441.1 807.4 513.2 656.2 489.6 753.2 996.6 529.9 355.5 409.5 330.7 419.0 561.4 562.5 1646.3 542.4 702.2 410.6 633.9 1373.2 805.2 700.3 1199.6 868.1 1302.9 930.5 833.2 1480.8 1231.2 1169.3 968.8 513.9 840.6 1089.3 1105.6 1106.1 2815.9 874.4 881.4 896.5 971.9 869.5 909.5 896.4 891.1 908.6 877.2 922.9 881.0 552.0 275.7 398.1 45.1 925.3 1129.4 1242.3 2031.6 1121.8 280.2 1365.2 1553.2 3479.9 1086.6 942.3 632.7 131.3 1223.1 714.3 1863.5 2752.8 1091.1 539.4 480.5 468.0 629.7 1009.6 524.6 44.0 1316.2 1094.7 591.2 813.0 575.6 521.4 554.3 660.7 1314.7 1602.3 212.0 51.7 1782.5 1125.0 1488.5 1376.5 1155.4 498.9 1010.5 1145.5 35.6 1451.7 562.9 785.8 35.7 65.5 1463.7 1950.7 357.7 726.2 1370.7 3811.3 2936.3 545.4 349.9 355.0 481.8 678.0 358.6 321.7 1721.9 1361.7 1481.9 816.5 1020.3 2147.9 1941.7 COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1151.3;skeletal muscle: 1332.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3614.3;Distal tubular cells: 3621.5;Proximal enterocytes: 2795.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034517 Supported Enhanced Mitochondria NA NA 230000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034517: AB_10603561" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.73e-4)" 209.1 252.9 323.0 42.8 339.7 113.3 178.7 373.1 436.0 138.1 349.2 322.6 164.2 124.6 72.3 284.6 136.9 32.6 1151.3 319.2 357.2 478.6 372.8 120.4 40.3 341.7 339.9 138.4 165.6 234.0 169.0 47.1 339.9 158.2 113.4 74.5 196.7 90.1 1332.7 213.2 211.9 51.1 332.9 153.2 290.6 101.2 353.1 64.4 185.0 705.9 54.3 179.8 179.1 355.3 144.9 165.5 106.8 169.7 115.9 105.8 428.3 180.0 100.8 118.3 130.5 459.9 148.7 240.8 377.3 116.5 188.4 217.9 117.5 181.8 56.4 188.7 493.2 324.2 166.6 559.8 220.3 310.6 231.2 193.8 161.6 113.4 91.2 125.4 104.4 187.8 243.6 115.5 94.0 360.0 203.5 450.0 196.6 257.2 854.3 194.9 170.6 368.8 167.5 227.9 202.2 210.3 175.0 225.0 374.8 146.0 115.7 345.5 186.9 107.5 181.4 174.4 118.7 265.8 274.7 183.1 194.9 264.5 113.5 1086.6 1062.7 933.1 458.0 1057.0 445.1 801.5 547.4 481.8 990.1 666.0 528.0 468.8 1016.6 469.6 926.3 677.6 783.4 1543.0 323.0 339.7 373.1 436.0 319.2 357.2 341.7 339.9 339.9 332.9 353.1 355.3 461.0 221.2 256.0 33.3 292.7 386.6 629.5 1166.0 377.9 239.1 433.2 536.2 3614.3 567.6 618.5 800.0 227.2 736.0 257.4 1960.0 3621.5 599.5 207.5 399.4 300.8 380.0 740.3 308.8 27.3 604.1 897.1 391.6 616.7 439.7 330.6 392.2 361.3 1234.9 875.0 141.3 33.7 1430.5 1043.6 485.2 651.9 360.8 351.6 456.6 912.4 30.0 711.7 461.5 314.1 15.6 39.4 505.4 1836.0 304.6 353.3 468.2 2795.9 2663.5 485.4 386.3 447.0 340.2 569.9 265.2 310.7 944.2 479.9 613.2 291.9 455.7 1576.9 915.9 COX6B1 "COX6B, COXG" ENSG00000126267 "Cytochrome c oxidase subunit 6B1" P14854 19 35648323-35658782 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 2453.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2710.8;Distal tubular cells: 2985.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004192 Supported Supported Mitochondria NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA004192: AB_1847180" "unprognostic (5.12e-2)" "unprognostic (1.86e-2)" "unprognostic (3.81e-2)" "unprognostic (1.22e-1)" "unprognostic (1.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.18e-1)" "unprognostic (6.16e-2)" "unprognostic (3.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.64e-1)" "unprognostic (1.88e-1)" "prognostic favorable (5.42e-4)" "unprognostic (2.10e-2)" "unprognostic (6.98e-2)" "unprognostic (5.74e-2)" "unprognostic (5.48e-3)" 322.3 211.6 733.9 206.6 741.0 465.2 371.1 780.8 935.9 291.0 758.1 598.9 427.0 197.2 633.9 410.0 329.7 245.8 1284.7 749.3 761.3 519.5 582.3 201.7 316.0 768.3 740.1 241.1 292.4 850.2 169.9 222.3 757.0 249.2 690.0 276.5 356.6 328.6 1467.0 264.7 351.3 342.8 735.4 193.3 336.8 107.0 759.7 426.3 270.5 2453.4 510.5 402.2 205.1 747.2 480.3 1219.5 479.2 649.4 665.5 701.3 455.3 383.4 641.0 684.8 686.4 1018.3 478.0 555.8 663.1 656.6 413.4 341.7 836.5 700.6 683.5 632.0 570.1 929.4 626.6 1014.1 521.1 835.0 454.9 800.2 906.5 619.5 361.1 606.3 690.4 577.8 616.9 783.0 714.9 1019.4 589.2 626.8 357.0 2445.6 811.5 502.1 525.9 930.4 1567.1 1035.9 434.4 484.5 615.9 1049.3 393.4 568.5 419.6 892.9 365.9 363.8 398.0 382.3 605.6 450.5 683.3 776.7 470.9 695.0 472.7 1138.1 1099.7 998.5 628.9 1228.5 607.0 1150.2 854.9 732.8 1140.2 956.3 839.9 744.3 1115.9 672.8 1178.4 1176.1 1138.3 2058.8 733.9 741.0 780.8 935.9 749.3 761.3 768.3 740.1 757.0 735.4 759.7 747.2 324.6 243.6 227.3 27.4 409.4 427.1 436.6 1071.1 373.3 143.5 498.4 615.2 2710.8 664.8 529.6 698.9 64.6 623.0 361.5 1496.0 2985.6 711.7 328.0 427.4 293.2 312.6 625.7 436.5 21.2 808.9 735.5 360.9 484.2 397.2 280.8 277.9 338.8 1270.7 1041.1 89.2 27.9 1277.1 736.5 800.2 705.9 942.4 327.7 582.7 748.8 18.7 807.7 351.1 435.6 16.1 31.6 863.0 1445.3 273.1 523.2 548.7 2291.0 2228.5 445.5 193.3 263.0 293.8 454.2 175.7 186.6 784.8 565.6 670.7 373.1 229.1 1277.5 717.0 COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014295, CAB016244" Enhanced Supported Mitochondria NA NA 210000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB016244: AB_2085703, HPA014295: AB_2668966" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (6.90e-2)" "unprognostic (3.37e-2)" "unprognostic (1.58e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-2)" "unprognostic (1.29e-1)" "unprognostic (3.51e-1)" "unprognostic (3.70e-1)" "unprognostic (8.86e-2)" "unprognostic (3.47e-3)" "unprognostic (1.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" 134.0 147.5 180.8 52.9 183.9 152.6 125.7 186.1 291.0 166.4 190.2 268.1 334.8 194.0 175.6 197.3 189.5 20.4 781.6 191.8 195.6 254.9 328.5 108.4 71.1 186.0 188.4 161.9 107.3 101.7 159.5 89.9 189.2 162.6 110.4 147.0 108.1 58.1 666.1 121.4 172.3 42.7 182.4 122.9 180.0 170.8 192.7 44.8 129.1 554.1 51.5 188.7 148.6 188.9 137.6 57.8 63.8 251.3 140.0 100.5 103.1 44.5 42.7 30.1 34.3 54.7 284.5 326.8 320.1 70.1 47.7 176.4 36.4 363.3 51.0 60.5 89.1 684.6 66.9 160.4 88.9 319.3 201.9 95.1 475.3 26.0 56.4 129.2 45.1 103.8 49.8 571.1 51.6 134.2 337.9 289.6 117.9 205.5 127.7 381.0 21.2 320.6 453.4 713.3 191.8 115.2 30.9 654.2 351.5 65.0 461.7 201.1 40.1 220.4 286.0 235.8 63.8 140.7 126.3 209.6 310.2 128.2 200.8 345.8 134.7 114.1 177.8 210.5 189.0 209.7 270.6 193.5 212.9 189.8 319.7 294.9 16.6 187.7 266.5 301.9 272.7 252.9 180.8 183.9 186.1 291.0 191.8 195.6 186.0 188.4 189.2 182.4 192.7 188.9 527.8 403.8 485.1 29.7 382.1 490.8 493.5 1431.9 279.4 217.6 561.3 642.7 2146.4 491.8 731.2 605.1 102.2 978.9 416.1 1263.2 2226.5 673.6 834.3 579.3 778.7 436.9 807.5 400.2 27.6 849.4 853.9 502.0 440.4 551.9 362.5 219.3 384.1 1855.5 1066.5 156.5 33.5 1221.3 1027.4 451.1 539.5 266.5 664.8 440.8 732.8 23.4 778.0 545.0 449.0 22.6 32.1 808.6 1338.7 587.5 412.2 448.4 2173.5 1791.0 702.9 282.0 493.0 367.1 555.9 1180.5 505.2 666.4 640.6 1784.9 452.1 428.0 1246.7 715.5 COX7A2 "COX7AL, COXVIIa-L" ENSG00000112695 "Cytochrome c oxidase subunit 7A2" 6 75237675-75250323 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 4705.1;Late spermatids: 3873.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (8.49e-2)" "unprognostic (2.56e-1)" "unprognostic (1.98e-2)" "unprognostic (2.15e-2)" "unprognostic (1.34e-1)" "unprognostic (5.67e-3)" "unprognostic (1.00e-1)" "unprognostic (1.65e-1)" "unprognostic (7.70e-2)" "unprognostic (2.73e-3)" "unprognostic (7.44e-2)" "unprognostic (1.74e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" 180.5 204.2 346.7 94.5 356.4 171.8 166.2 374.6 579.3 133.0 382.9 314.4 196.3 128.4 215.0 253.0 135.7 105.5 601.8 357.5 401.2 374.6 307.6 146.1 117.3 344.1 349.7 103.8 154.1 407.8 232.6 92.4 355.2 163.4 327.9 332.2 160.4 124.0 185.3 163.6 200.9 158.5 358.6 138.6 286.4 497.7 353.5 166.6 146.8 293.8 156.6 160.5 154.1 378.4 116.5 260.5 334.6 276.7 195.9 220.0 242.3 276.9 252.7 270.3 291.3 471.1 172.9 188.1 239.0 251.9 363.1 247.1 236.1 299.9 336.8 347.8 482.6 283.6 842.1 630.6 200.8 305.6 319.9 240.7 392.7 250.9 163.2 283.4 318.7 420.8 255.2 266.0 370.4 536.6 130.7 329.7 210.9 569.4 472.5 210.2 169.0 500.7 436.3 745.0 228.2 275.3 172.4 312.0 301.7 273.2 190.9 843.6 156.4 118.8 218.2 95.9 319.5 373.2 444.7 221.4 135.7 342.5 237.3 693.0 582.0 585.0 435.6 663.4 468.5 659.6 563.3 527.9 619.7 559.7 551.1 511.9 437.7 496.6 696.0 781.4 680.8 1055.8 346.7 356.4 374.6 579.3 357.5 401.2 344.1 349.7 355.2 358.6 353.5 378.4 370.9 304.5 371.3 15.0 391.8 553.7 624.1 2000.6 268.6 251.0 584.8 693.0 2518.6 630.5 1019.4 503.9 120.9 686.3 348.5 1504.8 2602.2 800.4 4705.1 460.2 288.0 382.5 663.0 354.3 18.9 1007.3 787.6 367.5 414.9 451.7 300.1 269.4 385.8 1485.8 870.3 154.8 22.4 1283.5 1468.9 484.8 499.6 3873.2 355.7 420.2 846.6 10.3 715.3 390.3 396.5 14.1 20.9 1157.5 1498.6 339.3 593.7 848.5 1790.7 2008.3 772.8 359.9 407.6 303.7 587.8 2905.4 230.0 627.9 626.4 818.3 381.9 336.4 1242.8 994.8 COX7C ENSG00000127184 "Cytochrome c oxidase subunit 7C" P15954 5 86617928-86620962 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2380.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4586.0;Distal tubular cells: 4724.9;Proximal tubular cells: 5650.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046647 Approved NA NA 39000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA046647: AB_2679736" "unprognostic (1.45e-1)" "unprognostic (1.74e-2)" "unprognostic (9.10e-2)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (1.04e-1)" "unprognostic (3.70e-1)" "unprognostic (4.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-2)" "unprognostic (1.21e-1)" "prognostic favorable (1.23e-5)" "unprognostic (4.56e-2)" "unprognostic (2.06e-1)" "unprognostic (1.46e-1)" "unprognostic (4.46e-2)" 338.6 433.9 600.9 274.3 610.7 314.7 324.9 620.1 771.4 329.2 657.2 563.0 545.8 271.8 402.9 420.1 288.0 194.7 1546.9 609.6 648.8 715.2 621.3 243.3 314.5 619.9 616.5 392.7 382.2 781.1 402.4 196.2 613.5 305.4 398.2 236.6 459.7 253.1 2380.2 274.3 537.4 207.5 614.4 270.0 429.7 174.6 624.6 370.8 328.0 1599.4 319.8 344.4 315.0 614.7 576.6 687.2 595.1 1043.0 551.4 550.5 653.4 432.8 364.4 298.2 416.7 806.4 989.9 794.6 459.2 342.3 799.3 594.8 539.3 876.2 487.2 585.2 829.5 623.6 1006.0 844.4 458.9 732.2 692.1 648.0 745.3 377.5 518.0 841.6 486.3 687.0 392.7 860.9 443.7 1209.9 766.2 954.2 594.7 593.0 1958.6 728.4 654.3 1426.2 909.4 1129.8 700.4 518.2 406.7 946.9 973.0 646.9 963.0 1008.6 449.2 254.2 470.5 448.4 846.6 832.8 1056.8 903.4 652.5 860.4 491.6 344.5 526.0 414.6 399.1 558.3 500.0 682.6 620.5 497.6 668.6 567.2 648.4 579.2 52.3 404.7 538.3 619.0 606.5 996.5 600.9 610.7 620.1 771.4 609.6 648.8 619.9 616.5 613.5 614.4 624.6 614.7 408.8 512.8 732.9 33.0 879.5 723.5 946.8 1663.7 715.4 276.2 1141.9 1079.4 4586.0 1574.2 959.9 1213.8 156.4 1271.2 657.5 1604.6 4724.9 1314.8 1011.8 856.3 538.7 570.2 916.6 651.1 24.6 1506.3 878.3 605.7 677.3 706.8 618.0 814.7 809.2 2748.0 1388.3 230.5 30.2 1829.4 933.8 1457.0 904.7 488.5 985.7 785.3 1115.3 18.7 1443.9 714.6 782.7 15.1 25.9 1114.6 1964.4 720.7 617.5 975.5 3353.2 5650.8 734.8 313.3 598.2 662.7 740.8 927.7 381.9 1319.3 935.4 1320.8 826.7 634.8 2108.4 1356.3 COX8A "COX, COX8, COX8-2, COX8L, VIII, VIII-L" ENSG00000176340 "Cytochrome c oxidase subunit 8A" P10176 11 63974620-63976543 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2341.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055942 Supported NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA055942: AB_2682979" "unprognostic (6.93e-2)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.02e-2)" "unprognostic (2.24e-1)" "unprognostic (7.70e-3)" "unprognostic (2.01e-2)" "unprognostic (2.12e-1)" "unprognostic (3.46e-1)" "unprognostic (6.49e-3)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic favorable (2.51e-6)" "unprognostic (2.70e-2)" "unprognostic (5.41e-2)" "unprognostic (1.13e-1)" "unprognostic (8.44e-2)" 322.0 443.8 421.6 134.1 435.5 292.0 286.8 470.0 544.7 259.3 524.0 516.1 337.8 236.1 121.2 612.5 246.8 78.4 1287.8 415.9 469.2 771.1 449.9 265.4 119.9 421.5 420.4 248.0 275.7 366.3 373.9 105.7 414.7 316.0 250.2 149.5 362.1 223.8 1523.9 362.0 381.5 132.3 427.7 277.0 467.3 96.7 480.4 206.6 342.9 1005.3 175.8 307.1 331.2 427.9 613.9 803.9 505.6 505.2 213.8 260.8 365.3 317.0 355.2 621.2 480.1 543.1 489.1 290.1 680.8 447.1 581.6 597.7 395.7 550.9 212.5 427.6 687.8 423.2 621.8 650.3 341.4 431.0 527.7 336.7 412.4 497.3 398.6 274.1 391.9 676.2 503.9 613.3 397.7 1600.5 613.8 1461.1 460.7 726.4 1401.4 473.9 406.3 1234.3 512.9 512.7 457.8 645.0 377.1 541.2 816.1 215.0 796.1 459.8 240.7 356.1 481.0 769.2 374.2 760.8 662.4 461.7 462.0 420.9 436.9 764.9 743.9 692.9 407.0 848.8 301.5 398.5 441.6 403.5 867.0 347.3 337.1 369.6 530.6 418.3 794.1 851.2 589.5 723.9 421.6 435.5 470.0 544.7 415.9 469.2 421.5 420.4 414.7 427.7 480.4 427.9 236.7 224.4 259.8 13.7 255.3 294.6 392.2 640.4 385.3 196.8 394.3 458.2 1263.1 424.7 396.1 437.7 73.0 451.2 305.9 1382.7 2341.9 453.1 9.6 271.6 217.2 215.7 721.6 272.9 12.5 483.1 559.6 246.1 395.0 305.1 224.5 209.3 227.4 811.5 927.5 107.7 16.8 1011.7 592.0 535.2 427.0 25.6 239.6 455.4 627.9 11.2 508.9 429.3 416.1 7.5 15.2 562.9 1103.8 221.2 393.2 419.8 1417.0 1658.2 345.2 187.5 157.8 256.0 339.9 74.0 55.5 844.0 370.9 366.9 290.4 203.7 1088.7 593.4 CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 176.0;Early spermatids: 226.2;Excitatory neurons: 233.7;Inhibitory neurons: 286.9;Late spermatids: 408.9;Oligodendrocyte precursor cells: 148.8;Oligodendrocytes: 128.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 12.1;U-266/70: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "unprognostic (4.90e-2)" "unprognostic (2.12e-2)" "unprognostic (3.00e-1)" "unprognostic (5.66e-2)" "unprognostic (1.92e-1)" "unprognostic (2.95e-5)" "prognostic favorable (5.06e-5)" "unprognostic (4.09e-4)" "unprognostic (2.73e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-2)" "unprognostic (2.42e-2)" "prognostic favorable (3.84e-9)" "unprognostic (3.33e-2)" "unprognostic (7.42e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-1)" 1.9 3.9 6.1 1.8 7.2 1.7 3.2 6.2 17.3 2.5 2.1 2.3 3.1 1.9 4.5 4.6 1.8 2.0 5.1 6.4 4.3 4.6 32.2 2.2 1.9 10.4 5.6 3.5 3.5 3.2 4.0 1.6 11.0 4.2 2.6 7.1 7.5 2.4 19.7 4.0 3.0 2.0 1.4 2.6 2.8 12.9 4.4 1.5 6.5 9.5 2.1 1.9 3.1 7.0 0.9 0.2 0.3 1.9 0.5 0.5 0.7 0.8 0.6 1.2 0.9 0.6 1.9 1.1 1.0 0.3 0.5 2.5 0.9 0.6 0.7 1.1 0.9 1.4 1.3 0.8 1.4 0.6 1.4 0.4 1.5 0.6 2.4 1.0 1.1 1.3 0.9 12.1 0.5 0.7 0.9 0.8 0.2 1.3 0.9 1.1 1.6 2.1 1.2 0.4 1.4 0.5 0.8 2.2 1.6 1.0 2.7 1.6 0.8 0.6 0.6 0.4 0.7 6.3 1.7 1.1 0.3 2.2 0.1 2.6 0.4 0.8 0.2 0.5 0.2 0.7 0.1 0.3 0.3 0.1 0.1 0.1 0.5 0.2 0.6 0.2 0.1 0.2 6.1 7.2 6.2 17.3 6.4 4.3 10.4 5.6 11.0 1.4 4.4 7.0 6.1 6.4 7.0 176.0 6.2 8.8 4.0 4.0 7.4 26.0 20.5 10.7 25.3 5.7 4.4 12.9 50.1 2.1 3.0 11.3 5.9 3.2 226.2 9.0 3.0 7.1 19.8 3.6 233.7 2.6 1.6 5.5 4.1 10.8 3.8 4.1 12.5 75.2 4.8 30.3 286.9 9.9 8.2 23.9 3.4 408.9 5.9 10.3 5.4 87.1 8.9 3.2 4.1 148.8 128.6 3.2 4.0 7.9 4.2 10.7 10.1 5.0 8.7 24.7 0.0 4.4 4.1 13.2 7.2 22.0 13.9 1.2 3.3 3.4 5.9 6.5 CRIPT HSPC139 ENSG00000119878 "CXXC repeat containing interactor of PDZ3 domain" Q9P021 2 46616416-46630176 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046080, HPA056765" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nucleoli fibrillar center" "HPA046080: AB_2679529, HPA056765: AB_2683230" "unprognostic (3.38e-2)" "unprognostic (4.08e-1)" "unprognostic (1.67e-1)" "unprognostic (7.51e-3)" "unprognostic (1.91e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.10e-1)" "unprognostic (6.07e-2)" "unprognostic (1.54e-2)" "unprognostic (3.38e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.54e-4)" "unprognostic (4.18e-2)" "unprognostic (1.43e-1)" "unprognostic (1.12e-2)" "unprognostic (4.42e-2)" 7.0 7.7 4.7 2.2 4.6 6.0 6.6 7.6 6.0 5.9 5.3 7.2 3.0 5.9 5.5 6.3 5.5 1.8 11.9 4.8 4.1 7.2 6.1 4.3 3.3 5.5 4.3 7.2 5.4 2.7 6.0 2.1 5.0 5.6 2.8 10.7 7.0 1.9 12.3 6.1 5.6 2.2 3.6 4.7 6.3 5.8 4.6 2.4 4.7 2.8 3.1 6.3 6.3 7.8 3.8 2.5 2.3 2.4 2.7 2.9 3.4 2.7 1.8 1.7 1.7 2.9 2.7 2.9 5.7 2.9 2.4 2.6 2.3 2.4 3.3 4.4 2.6 3.6 3.4 3.8 3.1 2.8 2.2 3.3 2.9 2.4 1.7 3.2 2.7 1.6 3.7 3.4 2.1 2.4 1.9 3.5 3.0 3.6 2.5 1.7 4.6 4.4 3.2 2.7 4.2 6.7 3.1 2.4 3.2 2.3 2.0 2.1 3.5 2.7 2.6 2.7 3.0 3.7 3.1 2.8 4.1 3.1 2.3 6.3 2.6 3.8 2.9 2.3 2.6 3.6 3.0 2.6 2.1 3.5 3.0 2.9 5.8 3.0 2.4 3.2 3.6 1.9 4.7 4.6 7.6 6.0 4.8 4.1 5.5 4.3 5.0 3.6 4.6 7.8 28.6 19.2 13.7 19.2 34.5 43.1 65.5 71.3 28.5 28.9 56.5 54.4 60.4 45.8 51.8 31.3 25.0 56.7 48.4 38.5 68.4 64.5 41.8 46.4 33.7 29.5 65.1 91.8 22.5 39.8 81.4 35.1 20.4 37.7 28.5 28.3 38.6 57.5 48.1 16.8 25.7 39.9 42.7 38.9 30.2 15.9 36.4 29.3 30.2 20.6 48.7 40.4 51.5 44.2 31.2 67.6 58.4 25.6 46.2 58.6 81.0 102.6 48.7 51.2 19.7 26.0 48.0 56.0 49.6 39.1 53.0 95.6 35.8 26.2 32.6 74.9 CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 141.9;Horizontal cells: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" Cytosol "HPA037577: AB_10672497" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (1.31e-2)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "prognostic favorable (6.82e-5)" "unprognostic (1.48e-3)" "unprognostic (1.67e-1)" "unprognostic (5.07e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.01e-1)" "prognostic favorable (6.44e-15)" "unprognostic (8.13e-3)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-1)" 31.8 22.3 33.3 8.9 35.3 29.4 27.1 36.4 36.9 24.4 22.8 26.5 10.8 23.3 16.9 15.9 29.1 17.4 60.0 36.6 29.3 22.5 62.7 22.9 10.4 27.4 31.5 38.7 34.7 22.4 30.8 13.5 28.5 25.3 9.9 52.8 21.7 22.1 96.7 50.4 16.7 17.1 28.8 14.0 24.6 34.4 35.2 12.6 34.0 64.8 10.3 26.0 18.4 31.4 1.4 4.2 6.3 7.5 16.7 8.4 13.8 5.0 8.9 6.2 4.5 6.8 3.3 9.8 3.8 10.5 5.9 8.5 6.0 5.2 4.3 9.8 5.5 6.4 8.2 9.4 6.4 8.0 8.5 9.9 7.5 4.8 7.6 7.0 4.4 7.5 12.7 16.2 5.6 5.3 6.8 9.4 17.1 17.8 5.0 11.5 9.1 4.6 4.5 7.8 10.1 3.8 8.3 7.5 4.5 8.0 10.0 5.5 5.5 8.7 5.3 13.5 3.6 15.0 10.8 7.9 5.3 3.5 5.3 4.1 3.5 5.4 5.7 4.8 4.7 5.0 5.5 6.1 3.6 4.6 6.6 6.9 1.8 7.5 8.0 2.6 4.9 5.3 33.3 35.3 36.4 36.9 36.6 29.3 27.4 31.5 28.5 28.8 35.2 31.4 11.7 12.8 18.2 48.0 12.6 17.0 9.7 5.1 8.0 141.9 10.6 8.6 34.7 14.3 11.6 7.3 27.1 8.0 10.0 17.2 29.4 5.4 24.2 28.1 7.5 9.2 7.1 3.0 30.3 4.7 5.6 19.8 12.8 15.4 14.7 10.8 8.6 47.3 3.6 101.0 26.0 7.4 6.1 8.5 12.5 8.7 31.4 7.2 16.0 10.3 6.2 34.4 10.3 13.0 13.6 6.0 6.0 39.9 8.5 11.6 10.5 11.6 23.8 27.5 19.7 14.5 14.6 29.1 15.0 4.4 17.5 9.3 9.1 8.4 6.0 9.8 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5623.2;heart muscle: 10683.1;skeletal muscle: 6972.0;tongue: 9406.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 2889.5;Cardiomyocytes: 6878.2;Muller glia cells: 1664.3;Proximal tubular cells: 7285.9" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ASC diff: 2663.1;fHDF/TERT166: 775.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" 1035.0 106.6 2466.0 113.9 3113.8 0.4 592.2 3032.2 5623.2 439.1 2077.7 678.9 24.6 351.4 179.1 312.2 204.0 71.7 10683.1 2424.9 2666.2 2123.2 37.2 253.4 15.0 3215.2 2856.7 136.0 50.6 24.9 209.2 107.8 3147.1 317.9 78.2 478.7 428.7 358.5 6972.0 317.3 158.5 338.1 2877.3 88.5 263.8 23.5 2815.5 20.9 477.7 9406.7 34.4 490.0 477.5 4060.6 0.1 0.5 0.1 45.0 2663.1 90.9 15.0 54.5 2.5 0.8 2.5 1.7 0.2 0.0 41.7 775.8 0.2 2.0 1.8 2.3 1.4 0.3 0.0 0.0 11.9 3.9 16.9 0.4 0.7 77.1 11.1 0.6 6.2 44.3 0.2 0.0 4.6 2.5 169.5 0.1 0.1 1.1 0.5 0.0 1.0 0.2 0.0 0.6 29.8 0.8 0.1 0.4 5.3 9.1 39.8 63.5 4.9 0.0 1.7 310.1 105.0 6.5 4.1 0.5 0.1 0.6 7.1 0.4 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2466.0 3113.8 3032.2 5623.2 2424.9 2666.2 3215.2 2856.7 3147.1 2877.3 2815.5 4060.6 38.4 83.3 4.1 96.0 51.3 174.9 2889.5 32.1 72.8 16.2 334.4 696.1 6878.2 84.4 15.2 1338.9 18.8 3.9 6.8 0.4 677.0 320.3 24.7 345.4 265.3 88.4 7.1 0.0 6.7 11.5 7.4 880.6 0.0 1008.4 0.0 16.1 35.7 0.7 5.8 10.1 12.6 2.4 8.2 0.3 85.8 12.6 228.6 67.7 483.8 11.2 3.6 1664.3 0.0 7.5 615.7 12.1 0.0 187.7 1.6 855.4 0.0 7285.9 23.2 59.4 138.1 799.9 1053.3 21.6 1.4 56.5 155.1 33.4 55.4 6.7 1.2 249.0 CWC15 "AD002, C11orf5, Cwf15, HSPC148" ENSG00000150316 "CWC15 spliceosome associated protein homolog" Q9P013 11 94962620-94973586 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 883.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039878 Supported Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles, Mitochondria" "HPA039878: AB_2676722" "unprognostic (1.97e-1)" "unprognostic (5.51e-2)" "unprognostic (1.66e-2)" "unprognostic (8.64e-2)" "unprognostic (3.81e-1)" "unprognostic (6.85e-2)" "unprognostic (1.29e-1)" "unprognostic (1.52e-1)" "unprognostic (4.84e-3)" "prognostic favorable (9.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.44e-1)" "unprognostic (1.34e-1)" "prognostic favorable (7.17e-4)" "unprognostic (5.23e-2)" 23.1 21.8 37.3 14.2 37.5 32.3 30.5 38.5 46.3 22.5 33.9 20.4 16.0 20.8 34.1 23.6 21.3 13.9 35.0 37.1 39.1 31.2 37.6 17.3 25.1 38.3 39.8 27.0 22.4 25.9 15.7 25.6 38.5 19.9 19.4 25.2 27.0 19.7 68.7 18.1 18.3 17.4 38.6 18.9 21.7 40.0 38.0 30.8 25.1 60.1 24.4 22.0 20.7 39.4 27.1 16.5 63.3 32.3 54.4 50.1 33.0 40.1 52.4 59.9 51.0 80.6 62.4 40.3 76.2 51.1 41.2 28.9 33.8 47.3 66.3 50.7 30.5 51.3 20.5 40.0 45.3 65.9 31.8 47.9 54.1 36.7 54.0 50.2 59.5 44.3 58.2 37.2 56.1 29.4 65.2 87.6 32.0 66.6 42.9 43.7 38.2 44.2 61.1 30.2 35.2 28.8 42.0 44.7 35.9 53.3 72.1 50.8 35.8 44.4 35.2 60.7 41.0 16.9 41.2 57.4 25.5 73.4 44.8 45.9 22.6 33.9 23.6 28.1 32.3 28.7 31.3 29.0 29.6 25.2 29.7 30.7 27.4 26.8 35.9 28.7 34.4 23.7 37.3 37.5 38.5 46.3 37.1 39.1 38.3 39.8 38.5 38.6 38.0 39.4 67.1 73.7 63.9 12.4 69.3 59.3 84.6 150.1 54.7 59.3 56.1 80.0 170.3 92.9 112.2 51.5 14.6 146.7 75.5 62.4 221.1 122.2 883.6 57.7 60.9 74.3 28.4 96.2 15.4 144.0 126.3 80.0 42.8 57.9 104.4 68.6 96.0 121.3 128.7 40.4 17.0 68.3 83.4 69.5 62.4 203.6 112.8 68.8 71.2 14.0 109.1 142.6 104.0 13.0 21.5 125.7 85.4 92.9 59.2 90.9 99.0 245.9 89.1 59.1 138.1 72.5 98.8 267.7 196.2 80.2 63.9 119.3 71.3 69.9 65.2 70.9 CXXC5 "HSPC195, RINF, WID" ENSG00000171604 "CXXC finger protein 5" Q7LFL8 5 139647299-139683882 "Predicted intracellular proteins" Transcription "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 317.0;Early spermatids: 714.2;Horizontal cells: 541.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "MAIT T-cell: 30.0;memory B-cell: 85.1;naive B-cell: 96.7;NK-cell: 71.9;plasmacytoid DC: 59.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 210.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036508, HPA058148" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA036508: AB_10673620, HPA058148: AB_2683621" "unprognostic (3.08e-2)" "unprognostic (9.03e-2)" "prognostic favorable (2.40e-4)" "prognostic unfavorable (4.10e-7)" "unprognostic (2.91e-1)" "unprognostic (2.05e-1)" "unprognostic (1.11e-3)" "unprognostic (2.28e-2)" "unprognostic (2.12e-1)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (2.79e-2)" "unprognostic (2.63e-2)" "unprognostic (8.02e-2)" "unprognostic (1.44e-1)" "unprognostic (7.26e-2)" "unprognostic (1.57e-1)" 26.5 20.6 48.9 17.6 65.6 46.9 21.5 103.6 64.5 29.2 36.4 17.5 10.8 15.1 30.0 25.6 29.8 20.1 30.4 56.2 48.2 70.7 88.1 16.1 30.2 91.5 65.1 5.0 61.2 28.0 43.6 15.9 84.0 15.3 11.6 38.7 53.9 18.3 80.1 24.8 22.5 9.1 66.5 34.5 21.0 51.8 61.4 34.3 22.5 21.5 24.7 14.8 23.9 106.4 36.5 30.1 32.6 12.3 44.5 60.6 12.7 23.3 35.3 9.9 19.5 66.8 36.0 47.4 101.0 62.5 59.7 40.5 6.7 17.9 4.7 5.2 11.5 70.5 25.8 47.0 19.2 16.0 1.8 21.8 4.0 16.7 4.8 95.6 2.7 1.5 67.8 7.6 72.6 94.7 17.2 51.1 39.4 39.2 8.5 30.8 66.5 73.5 75.3 26.0 103.0 106.3 8.3 210.6 18.0 71.2 115.5 74.2 14.6 80.2 15.6 38.8 21.4 27.3 62.4 89.9 121.2 5.3 45.6 1.1 6.6 0.6 9.7 1.4 30.0 85.1 0.9 6.8 5.5 96.7 0.5 2.6 1.8 71.9 0.6 59.0 1.4 10.7 48.9 65.6 103.6 64.5 56.2 48.2 91.5 65.1 84.0 66.5 61.4 106.4 22.9 48.1 18.8 24.5 120.4 26.3 14.8 41.9 8.6 232.0 41.0 67.8 49.3 105.8 32.5 147.1 25.0 2.9 90.2 18.6 317.0 125.1 714.2 47.1 53.9 43.6 18.6 52.2 18.7 144.9 23.9 47.8 24.5 53.7 21.5 41.9 36.0 131.8 38.4 541.8 8.7 50.7 61.1 35.6 92.1 200.3 39.1 32.2 60.5 15.0 40.9 220.5 195.7 16.6 44.3 93.9 17.5 30.5 114.1 34.1 22.6 200.0 38.6 49.1 13.1 150.9 48.5 14.2 13.9 15.7 20.9 37.6 21.1 25.1 27.0 21.4 DCTN3 DCTN-22 ENSG00000137100 "Dynactin subunit 3" O75935 9 34613545-34620523 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044905 Approved Approved Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoli "HPA044905: AB_10960996" "unprognostic (3.38e-1)" "unprognostic (4.13e-2)" "unprognostic (3.47e-1)" "unprognostic (6.79e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.92e-3)" "unprognostic (9.88e-2)" "unprognostic (4.41e-2)" "prognostic favorable (2.10e-5)" "unprognostic (1.26e-3)" "unprognostic (4.24e-3)" "prognostic favorable (5.76e-11)" "unprognostic (3.06e-1)" "unprognostic (2.25e-1)" "unprognostic (3.22e-1)" "unprognostic (4.43e-2)" 72.9 87.9 98.3 33.7 104.6 107.3 72.2 97.0 123.5 80.6 92.9 81.1 42.0 72.9 46.8 98.5 66.4 38.7 127.1 106.0 103.3 88.6 67.0 60.8 48.0 97.1 97.2 78.7 76.5 94.4 108.4 40.7 102.4 68.2 39.0 57.0 69.2 51.4 152.5 111.1 51.1 53.6 94.1 58.7 75.6 36.3 100.3 81.3 71.5 114.4 59.0 69.5 79.2 95.6 147.1 120.7 110.1 115.6 95.1 132.3 45.1 122.7 112.8 166.4 130.2 77.7 53.8 67.0 74.6 161.8 58.4 57.4 101.0 128.3 105.6 211.9 126.5 44.9 202.9 68.5 102.6 118.8 131.3 117.5 109.4 115.6 75.0 81.4 111.1 123.6 54.2 135.3 147.4 120.9 151.4 320.0 33.4 61.0 192.7 75.2 59.7 93.4 81.5 51.2 36.5 93.3 90.9 82.7 48.0 32.2 110.6 134.5 102.7 104.6 84.1 120.1 121.0 90.6 126.0 45.5 164.1 68.6 217.4 235.2 131.1 187.4 99.9 139.4 92.1 88.4 106.0 106.8 133.8 94.7 83.6 98.9 114.4 102.2 150.3 136.1 179.1 152.5 98.3 104.6 97.0 123.5 106.0 103.3 97.1 97.2 102.4 94.1 100.3 95.6 103.7 32.1 38.3 13.1 61.3 101.6 111.8 180.7 82.0 83.2 97.3 146.9 86.1 77.2 91.8 80.9 25.0 128.8 105.6 74.1 207.4 127.5 14.3 78.6 98.8 79.2 74.7 115.7 16.8 154.6 111.9 97.9 56.6 67.1 87.5 82.4 88.5 84.9 133.8 74.0 16.2 64.9 91.6 88.8 99.0 21.1 103.5 76.8 149.4 5.6 94.9 212.9 125.7 7.5 16.8 126.7 84.5 122.6 89.1 54.7 89.0 240.2 95.0 96.7 59.2 82.0 150.5 82.2 72.9 109.9 142.6 99.7 95.7 143.2 61.6 96.6 DCTN6 WS-3 ENSG00000104671 "Dynactin subunit 6" O00399 8 30156319-30183639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024049, HPA024558" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" "Plasma membrane" "HPA024049: AB_1847524, HPA024558: AB_1847525" "unprognostic (1.28e-1)" "unprognostic (8.32e-3)" "unprognostic (1.65e-2)" "unprognostic (1.88e-1)" "unprognostic (1.69e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (7.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-2)" "unprognostic (9.26e-2)" "prognostic favorable (5.42e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-1)" "unprognostic (7.54e-2)" "unprognostic (1.43e-1)" 50.6 54.1 48.0 26.6 51.1 43.7 53.0 51.8 74.1 32.3 42.3 37.5 23.8 38.2 43.5 34.3 30.1 32.8 75.6 50.4 54.8 54.2 46.7 34.0 28.3 50.8 49.8 41.5 32.0 72.8 29.7 53.6 51.1 34.7 36.2 42.4 33.6 36.7 36.6 29.0 26.1 42.6 52.9 27.6 31.9 21.9 50.5 37.8 54.6 43.5 31.2 45.8 31.6 58.6 53.6 51.9 64.4 33.8 59.3 80.7 42.1 72.8 87.0 70.4 74.9 33.6 35.8 41.0 76.0 78.8 64.9 39.6 46.1 64.2 83.8 32.4 34.3 57.8 40.9 54.5 45.8 33.6 47.4 68.2 90.4 51.2 54.8 61.5 65.2 58.0 66.4 44.3 77.0 41.7 62.4 53.0 51.6 93.8 32.0 32.4 48.7 35.3 104.6 54.1 105.4 60.0 42.7 53.0 77.9 32.4 50.4 48.3 60.8 37.4 128.9 31.9 52.4 18.1 22.2 51.8 69.7 38.1 68.1 16.7 13.5 5.0 8.1 15.8 9.1 7.1 7.5 9.8 15.9 5.3 9.5 11.4 3.7 11.2 15.9 20.8 8.1 6.8 48.0 51.1 51.8 74.1 50.4 54.8 50.8 49.8 51.1 52.9 50.5 58.6 61.3 25.6 39.7 19.9 34.9 57.2 91.3 127.1 25.6 36.4 45.4 43.2 83.4 47.1 85.3 44.1 14.6 88.5 48.9 28.1 123.3 94.5 18.0 32.5 37.2 58.7 40.8 28.2 19.0 84.5 87.7 56.6 25.0 39.6 46.9 44.0 45.7 42.7 71.4 26.9 17.3 31.6 91.6 43.9 54.8 12.5 80.8 43.2 69.4 15.0 58.4 63.3 17.5 17.6 21.3 91.1 43.1 75.2 32.3 48.8 36.3 147.1 71.6 40.3 52.6 63.1 66.0 44.2 47.3 38.0 63.5 203.6 59.8 49.5 33.0 95.0 DCUN1D5 "FLJ32431, MGC2714" ENSG00000137692 "Defective in cullin neddylation 1 domain containing 5" Q9BTE7 11 103050686-103092194 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050863 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoli Nucleoplasm "HPA050863: AB_2681259" "unprognostic (4.47e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (1.47e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (4.62e-4)" "prognostic unfavorable (2.01e-7)" "unprognostic (1.92e-3)" "unprognostic (1.21e-2)" "prognostic favorable (9.52e-5)" "unprognostic (2.08e-2)" "prognostic unfavorable (4.12e-4)" "unprognostic (2.64e-3)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-2)" "unprognostic (1.43e-3)" 15.8 14.6 11.9 4.2 12.7 4.7 13.2 16.6 17.5 11.3 7.9 11.3 1.4 11.1 3.8 21.4 10.3 1.8 23.9 13.3 12.8 14.3 13.7 11.0 5.1 11.8 13.0 9.1 14.2 3.0 13.0 3.3 12.1 11.3 2.2 7.5 12.2 3.0 31.3 11.8 9.4 2.7 13.2 12.3 13.3 18.5 13.5 4.5 9.2 7.7 4.1 11.9 12.1 13.0 18.2 14.5 18.8 16.3 11.6 13.2 10.0 17.9 6.8 9.0 12.7 51.2 24.8 8.0 32.8 13.3 29.0 21.3 24.3 24.0 16.1 9.7 22.4 21.6 16.2 22.3 18.7 33.7 12.4 7.6 23.8 17.7 22.8 18.3 18.1 32.6 26.3 0.1 10.5 21.6 24.4 46.5 24.5 33.6 32.9 9.5 15.1 22.4 15.4 33.9 12.8 11.0 10.0 21.8 21.4 25.1 20.4 22.4 4.0 12.4 14.8 16.6 17.6 7.8 12.5 33.0 7.9 31.4 13.0 12.8 6.6 6.5 8.7 8.5 10.2 11.3 10.8 9.5 9.5 9.3 9.3 10.3 2.5 15.1 7.1 11.1 11.8 9.3 11.9 12.7 16.6 17.5 13.3 12.8 11.8 13.0 12.1 13.2 13.5 13.0 24.9 16.0 11.0 26.8 30.2 79.5 63.2 101.6 38.1 11.7 34.4 36.2 30.7 15.7 42.8 9.2 8.4 57.2 29.3 8.2 49.0 59.5 5.0 26.5 38.2 27.2 14.4 52.1 50.7 55.6 88.6 35.6 21.9 25.3 15.8 37.3 16.1 25.3 44.7 6.7 39.6 17.9 67.1 29.8 32.4 8.4 14.3 22.7 30.2 15.9 26.5 18.9 15.5 25.6 27.5 63.1 12.2 19.5 52.8 92.6 8.6 39.2 28.0 14.1 26.3 31.5 74.6 121.6 119.8 59.0 83.7 43.8 30.9 59.8 23.2 73.0 DDO ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.4;Muller glia cells: 8.2;Oligodendrocytes: 13.3;Paneth cells: 8.5;Proximal enterocytes: 8.5;Proximal tubular cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.5;RPMI-8226: 15.9;U-937: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" 1.9 8.2 4.5 0.8 7.0 1.4 2.5 5.0 4.8 1.9 4.3 2.3 7.4 2.1 2.7 0.8 4.9 2.9 18.4 4.4 4.5 10.6 11.1 3.2 1.0 5.4 4.9 0.3 2.6 5.3 1.2 1.6 5.3 2.0 3.2 2.4 4.2 2.3 10.9 0.4 7.0 2.2 4.8 2.1 1.1 0.1 4.7 0.4 1.3 7.4 0.2 1.6 0.9 5.9 0.2 0.0 0.0 0.1 0.0 0.2 1.1 0.1 5.4 1.3 0.9 0.0 0.1 0.0 0.7 0.7 11.5 0.0 0.0 0.0 2.3 5.0 0.0 5.1 0.1 4.3 1.6 0.0 0.0 0.1 0.0 2.7 0.1 2.3 0.0 0.0 0.0 1.9 4.5 0.0 0.0 0.2 0.0 0.0 0.1 0.1 3.0 15.9 0.0 4.9 0.1 0.2 0.0 0.5 0.6 0.0 0.7 1.1 0.9 1.0 0.1 0.0 2.6 0.1 0.4 0.0 2.0 17.4 0.0 0.0 2.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 1.1 1.0 0.0 0.0 1.1 4.5 7.0 5.0 4.8 4.4 4.5 5.4 4.9 5.3 4.8 4.7 5.9 1.1 0.0 0.0 4.9 0.0 0.0 0.7 0.7 0.6 0.0 1.4 1.1 17.4 0.0 0.4 0.0 2.1 0.2 0.1 1.8 3.9 4.5 0.3 3.6 0.5 0.7 4.2 0.0 0.0 2.2 0.2 0.6 0.0 0.9 0.0 0.1 2.5 4.9 1.7 0.0 0.1 6.0 0.0 3.1 0.4 0.0 0.3 1.6 0.0 0.0 2.0 8.2 0.0 3.5 13.3 0.8 8.5 0.0 0.0 0.4 8.5 12.9 2.2 0.2 0.0 2.1 1.2 0.0 0.0 0.2 0.0 0.0 0.2 0.3 5.0 0.5 DEXI MYLE ENSG00000182108 "Dexi homolog" O95424 16 10928891-10942468 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 106.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041511 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" Cytosol "HPA041511: AB_10796675" "unprognostic (4.14e-1)" "unprognostic (8.52e-2)" "unprognostic (1.29e-1)" "unprognostic (9.70e-3)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (1.19e-2)" "unprognostic (4.71e-2)" "unprognostic (3.20e-1)" "unprognostic (1.47e-2)" "prognostic favorable (4.23e-4)" "unprognostic (5.21e-2)" "unprognostic (1.33e-3)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.75e-2)" "unprognostic (1.83e-2)" 34.7 82.2 52.6 10.8 54.2 5.5 29.3 59.3 60.1 35.3 44.3 46.8 14.6 34.5 23.4 25.0 34.1 11.2 101.6 43.0 54.0 33.1 91.3 27.3 12.5 58.7 55.6 34.6 29.8 20.9 38.0 13.0 62.2 39.1 7.9 6.2 23.5 20.3 128.4 27.6 24.9 15.5 51.8 30.5 34.0 14.8 67.9 11.6 28.4 58.7 10.5 33.5 28.9 45.5 18.1 25.9 13.6 24.1 54.1 29.5 12.5 27.2 28.0 17.4 16.5 12.2 18.5 21.4 39.9 31.0 19.0 22.9 16.2 29.3 14.9 50.4 36.4 10.7 17.1 52.3 30.9 18.3 19.3 30.2 33.1 17.1 19.7 28.2 25.3 29.7 24.5 20.8 19.6 31.9 22.9 19.9 19.1 22.3 26.5 21.2 18.0 32.8 21.9 13.3 28.0 24.7 26.0 28.2 22.6 11.4 22.5 31.6 28.1 17.5 18.7 41.9 18.0 27.2 22.6 6.2 15.4 38.7 20.2 1.3 0.5 7.2 4.6 0.6 4.2 0.5 4.0 5.4 0.3 4.1 4.7 4.6 0.5 3.0 0.2 2.0 3.3 1.0 52.6 54.2 59.3 60.1 43.0 54.0 58.7 55.6 62.2 51.8 67.9 45.5 23.3 6.4 12.1 10.1 12.4 33.3 40.5 9.7 21.6 18.8 19.1 26.0 0.0 41.5 5.9 27.6 12.5 28.1 11.5 8.5 76.3 24.8 8.1 10.5 21.4 27.1 14.9 15.6 8.0 36.2 21.4 33.8 10.7 7.4 1.3 30.4 46.1 106.3 41.2 23.5 13.3 14.5 14.2 15.5 15.8 14.9 75.2 14.6 16.0 8.4 10.7 57.0 18.6 3.5 6.7 31.2 10.1 85.7 14.9 70.7 17.8 70.9 8.8 14.8 19.7 29.9 26.1 3.8 3.7 18.4 32.5 11.6 19.2 38.4 17.5 39.0 DGLUCY "C14orf159, FLJ39975" ENSG00000133943 "D-glutamate cyclase" Q7Z3D6 14 91060333-91225632 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Collecting duct cells: 29.5;Cytotrophoblasts: 30.9;Endometrial ciliated cells: 29.4;Granulosa cells: 49.8;Hofbauer cells: 31.7;Theca cells: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 200.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041423, HPA052932" Approved Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041423: AB_10795540, HPA052932: AB_2681991" "unprognostic (5.02e-2)" "unprognostic (1.01e-2)" "unprognostic (1.56e-1)" "prognostic favorable (4.28e-4)" "unprognostic (1.28e-1)" "unprognostic (2.26e-1)" "unprognostic (3.58e-2)" "prognostic favorable (9.48e-5)" "unprognostic (3.56e-1)" "prognostic favorable (7.28e-4)" "unprognostic (2.30e-1)" "unprognostic (1.74e-1)" "prognostic favorable (3.77e-15)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" "unprognostic (2.75e-2)" "unprognostic (2.57e-3)" 23.9 32.2 38.5 21.4 46.0 21.7 16.7 53.5 49.2 25.0 76.1 33.5 25.1 26.0 17.2 28.4 38.6 22.6 122.3 36.6 39.8 35.6 24.9 25.0 21.6 45.5 51.3 22.9 16.8 47.9 21.5 16.6 42.1 22.8 30.4 8.3 32.2 34.1 143.0 25.6 23.7 32.0 38.0 33.6 38.1 19.0 45.4 27.3 30.1 163.6 19.9 31.9 20.2 45.2 6.2 16.4 8.0 20.1 32.8 30.6 21.0 6.6 17.7 19.3 19.6 10.9 46.7 41.3 46.0 18.8 24.9 18.0 23.0 24.7 7.9 22.8 9.5 27.7 9.1 13.8 47.8 28.5 38.2 47.5 10.5 10.6 4.0 25.3 34.6 22.8 14.0 54.4 18.4 1.4 22.7 27.0 16.4 0.8 1.4 38.2 15.7 30.9 32.7 25.9 22.4 11.2 10.4 17.8 7.3 8.4 32.0 24.5 24.7 5.7 4.8 17.1 5.9 30.9 23.8 14.0 29.6 36.8 3.8 67.5 48.8 30.8 30.1 69.4 30.3 34.0 19.3 24.5 72.9 22.4 15.9 20.0 200.5 21.0 60.7 22.0 45.2 29.0 38.5 46.0 53.5 49.2 36.6 39.8 45.5 51.3 42.1 38.0 45.4 45.2 19.2 28.9 16.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 11.5 13.2 0.0 0.0 5.6 29.5 0.0 30.9 12.5 0.0 21.5 17.6 0.0 29.4 14.8 6.2 0.0 0.0 0.0 5.8 15.8 7.4 0.0 25.0 7.6 49.8 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 7.2 0.0 0.0 0.0 0.0 6.3 0.0 0.0 2.7 0.0 0.0 17.0 5.1 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 16.8 8.7 35.6 0.0 0.0 DMAC1 "C9orf123, MGC4730, TMEM261" ENSG00000137038 "Distal membrane arm assembly complex 1" Q96GE9 9 7796500-7888380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 500.8;Hofbauer cells: 221.7;Proximal tubular cells: 254.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA014585 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 7: Non-specific - Mitochondria" "HPA014585: AB_1845803" "unprognostic (1.48e-2)" "unprognostic (3.74e-2)" "unprognostic (7.23e-3)" "prognostic favorable (4.15e-4)" "unprognostic (2.78e-2)" "unprognostic (2.79e-3)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (3.26e-3)" "unprognostic (3.65e-1)" "prognostic favorable (1.96e-11)" "unprognostic (1.75e-1)" "unprognostic (4.19e-1)" "unprognostic (2.35e-1)" "unprognostic (7.41e-2)" 10.6 11.9 16.8 7.7 17.0 6.2 12.4 17.5 21.0 9.3 9.0 12.6 9.8 10.0 11.8 9.3 11.0 6.3 25.4 16.3 17.8 15.9 10.2 7.2 10.0 15.2 15.0 13.2 9.2 21.8 12.3 8.1 15.6 11.9 9.9 9.0 14.3 11.6 43.1 8.5 9.1 8.1 15.1 10.4 10.7 7.0 16.0 20.6 11.8 29.8 8.9 11.5 8.3 16.9 18.5 21.8 19.7 12.3 15.4 19.1 13.3 11.0 7.7 11.5 10.4 9.9 11.3 27.1 5.6 9.8 15.0 9.8 21.2 18.8 11.6 16.2 24.3 49.3 32.7 31.8 15.6 17.2 6.7 24.1 13.2 9.1 13.9 10.6 11.0 24.3 9.2 5.6 12.2 15.7 25.1 39.7 17.5 15.6 10.5 19.0 11.1 16.4 13.2 17.6 31.5 17.6 12.0 8.0 14.1 13.5 10.5 10.5 14.0 8.8 14.2 11.6 7.7 7.0 12.0 14.5 7.4 14.3 9.0 2.0 10.1 4.5 11.5 12.2 17.4 26.5 15.7 12.3 12.6 22.5 20.5 16.5 1.6 20.8 9.8 13.1 19.9 19.6 16.8 17.0 17.5 21.0 16.3 17.8 15.2 15.0 15.6 15.1 16.0 16.9 42.2 70.5 48.5 0.0 15.7 0.0 0.0 0.0 0.0 0.0 69.5 81.5 0.0 0.0 24.1 101.2 0.0 113.6 13.9 0.0 500.8 94.2 0.0 81.4 64.3 30.0 0.0 0.0 0.0 90.7 96.3 32.8 0.0 58.6 27.8 127.7 0.0 0.0 221.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 25.8 0.0 0.0 0.0 0.0 62.4 0.0 0.0 3.1 0.0 0.0 254.7 70.7 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 55.4 17.3 79.3 0.0 0.0 DMAP1 "DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4" ENSG00000178028 "DNA methyltransferase 1 associated protein 1" Q9NPF5 1 44213455-44220681 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028419, CAB033018, HPA069527" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "CAB033018: AB_2230431, HPA028419: AB_2672597, HPA069527: " "unprognostic (1.91e-3)" "unprognostic (2.79e-3)" "unprognostic (4.90e-2)" "unprognostic (6.52e-2)" "unprognostic (4.80e-2)" "unprognostic (1.43e-3)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.72e-2)" "unprognostic (7.32e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" "unprognostic (1.86e-2)" "unprognostic (2.29e-3)" "unprognostic (1.53e-1)" "unprognostic (1.33e-1)" "unprognostic (3.09e-1)" "unprognostic (2.04e-2)" 19.3 53.8 31.7 13.2 32.3 14.6 20.6 32.4 37.4 22.8 30.1 21.1 13.5 20.3 9.7 18.9 20.0 11.7 26.5 32.6 31.0 26.0 28.7 17.9 16.9 30.9 31.2 26.6 33.9 25.5 25.1 14.6 31.0 24.3 11.7 19.5 21.3 13.2 36.1 21.3 22.0 10.7 30.2 27.6 24.2 25.2 32.0 20.9 23.4 25.2 14.4 21.6 19.5 32.8 21.1 22.2 30.6 16.0 15.5 14.6 35.0 18.3 24.4 43.3 37.2 35.7 25.9 31.5 24.1 29.7 16.9 17.0 27.4 23.6 22.8 25.0 44.3 29.0 41.2 36.2 28.0 28.7 21.2 23.0 25.8 35.8 20.5 27.9 28.3 29.5 20.6 28.2 25.7 24.5 40.4 35.9 43.6 10.8 27.0 40.5 30.8 34.5 23.1 26.2 28.0 23.3 34.4 24.3 35.8 29.1 20.1 32.8 27.5 12.2 36.5 28.5 37.6 33.9 21.8 25.4 23.1 28.2 20.6 45.0 23.1 23.1 30.8 20.9 31.9 27.7 31.2 32.2 24.0 28.3 27.8 27.5 9.9 43.8 17.6 19.2 37.5 24.6 31.7 32.3 32.4 37.4 32.6 31.0 30.9 31.2 31.0 30.2 32.0 32.8 23.4 32.1 23.8 11.1 23.6 19.2 25.9 36.4 19.4 43.0 18.6 22.2 22.8 18.6 24.5 11.0 25.0 72.6 30.9 32.8 29.4 31.9 41.9 15.4 14.1 23.9 54.4 25.7 10.4 41.5 34.4 20.5 28.5 14.8 27.3 38.1 23.6 19.1 32.6 23.5 12.1 32.0 44.7 22.3 12.7 69.2 18.0 15.4 17.8 4.7 26.3 46.3 25.7 9.0 9.6 22.9 38.6 17.7 26.8 9.7 46.9 36.2 26.8 56.1 6.6 23.9 25.1 24.5 47.2 15.7 17.8 52.4 25.5 29.3 29.8 16.3 DNAJA2 "CPR3, DNAJ, DNJ3, HIRIP4" ENSG00000069345 "DnaJ heat shock protein family (Hsp40) member A2" O60884 16 46955362-46973674 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049789, HPA060538" Approved Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 67000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Cytosol" "Intermediate filaments" "HPA049789: AB_2680883, HPA060538: AB_2684315" "unprognostic (7.68e-3)" "unprognostic (1.05e-2)" "unprognostic (4.77e-2)" "unprognostic (3.67e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.81e-4)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.53e-2)" "unprognostic (5.41e-2)" "unprognostic (2.12e-1)" "prognostic favorable (1.19e-9)" "unprognostic (9.22e-2)" "unprognostic (2.28e-1)" "unprognostic (9.22e-2)" "unprognostic (4.69e-2)" 20.7 25.2 30.5 14.2 32.6 23.9 19.7 33.9 40.5 17.9 32.2 21.3 20.0 22.0 28.6 21.5 17.4 16.4 36.0 32.3 31.9 28.0 36.0 16.6 19.7 29.8 30.2 22.0 17.0 29.2 16.4 19.9 30.5 21.8 19.0 29.5 17.1 20.6 37.1 21.1 20.5 17.0 31.0 22.7 19.2 24.9 31.2 20.3 22.2 38.7 21.4 21.6 18.2 30.5 23.1 26.9 26.6 22.8 35.7 34.1 40.3 29.4 35.4 43.4 20.5 23.7 23.6 37.1 23.2 31.9 18.6 35.0 43.0 30.2 49.8 8.8 36.0 27.2 12.8 50.7 42.7 41.7 36.3 36.5 34.6 25.2 23.7 37.9 30.4 14.7 31.7 12.0 37.0 25.4 30.1 57.5 40.6 21.1 39.6 34.3 48.7 44.1 52.7 24.1 36.1 23.1 34.9 52.1 33.4 26.1 20.3 32.2 31.6 25.4 16.0 18.5 25.1 29.3 21.7 49.0 26.9 35.5 21.8 13.1 10.3 13.5 9.8 12.7 12.9 11.3 13.2 11.2 9.4 8.4 12.9 13.1 10.7 12.8 11.3 6.7 17.2 9.7 30.5 32.6 33.9 40.5 32.3 31.9 29.8 30.2 30.5 31.0 31.2 30.5 64.3 51.3 35.9 11.8 78.4 126.9 75.1 56.4 101.3 38.8 37.5 28.4 100.3 40.0 48.2 40.5 18.8 85.2 76.1 67.6 90.1 73.4 93.3 86.9 76.8 52.2 52.0 49.4 16.6 62.2 72.5 66.2 54.0 72.1 53.9 52.7 31.1 54.9 56.5 37.0 15.3 55.6 52.9 42.5 86.4 56.8 50.1 65.1 72.9 12.2 72.3 60.5 45.3 10.1 11.0 71.2 64.2 59.0 70.7 61.6 83.3 111.4 67.6 43.7 52.6 63.4 99.4 177.7 106.0 111.1 120.5 172.4 89.6 131.4 62.6 87.3 DNAJA4 PRO1472 ENSG00000140403 "DnaJ heat shock protein family (Hsp40) member A4" Q8WW22 15 78264086-78282196 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 138.4;tongue: 144.6" "Group enriched" "Detected in many" 5 "Early spermatids: 673.9;Late spermatids: 1608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 33.6;CAPAN-2: 43.3;HeLa: 47.3;MCF7: 33.6;RT4: 85.2;SCLC-21H: 53.3;SiHa: 42.7;THP-1: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004646, HPA041790" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "CAB004646: AB_426011, HPA041790: AB_2677674" "unprognostic (8.41e-2)" "unprognostic (2.48e-1)" "unprognostic (3.00e-2)" "unprognostic (8.20e-3)" "unprognostic (1.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.86e-2)" "unprognostic (7.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.08e-7)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (9.01e-2)" "unprognostic (2.93e-2)" 16.5 20.0 60.6 14.0 67.7 63.7 12.6 62.6 138.4 14.1 45.6 18.0 13.8 8.3 20.2 15.8 38.9 11.2 123.3 68.6 93.1 26.7 3.3 19.7 11.3 65.7 73.3 12.1 6.6 7.4 30.9 9.5 89.8 26.7 18.5 33.0 15.6 15.6 123.2 28.6 16.3 19.6 59.8 13.5 24.2 78.3 73.5 9.4 9.6 144.6 12.4 29.6 13.6 71.3 33.6 0.2 0.0 0.0 0.0 0.0 0.1 4.1 0.0 1.1 0.5 0.0 43.3 0.0 0.3 3.2 0.0 31.3 0.0 0.0 0.1 0.1 0.0 19.9 47.3 0.0 9.4 0.0 20.6 3.6 4.1 2.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 33.6 0.0 0.0 0.0 14.4 0.3 0.0 0.0 0.0 0.1 85.2 53.3 0.0 42.7 8.6 3.6 2.3 32.4 39.8 0.5 0.0 8.7 4.0 0.4 0.6 2.4 0.0 0.1 4.2 0.0 0.0 0.3 1.1 0.6 0.3 1.0 0.7 0.9 0.9 0.4 0.1 1.7 1.4 0.0 0.1 0.4 0.2 0.5 0.6 60.6 67.7 62.6 138.4 68.6 93.1 65.7 73.3 89.8 59.8 73.5 71.3 41.9 6.4 4.8 12.7 10.0 28.8 209.9 14.0 2.2 19.6 44.6 29.2 43.6 2.8 33.5 7.3 81.3 1.9 6.7 55.5 1.9 1.3 673.9 124.0 11.4 18.9 100.3 92.8 16.6 2.4 3.8 18.3 21.4 41.8 36.9 7.5 6.8 0.2 16.5 6.7 24.0 34.9 10.2 9.5 81.7 1608.0 10.2 51.7 51.6 6.5 3.5 10.3 6.2 15.1 19.0 5.1 55.3 11.3 3.7 115.8 15.8 7.2 138.9 22.6 6.6 17.4 20.2 33.8 27.7 16.9 46.7 6.8 37.1 6.9 42.1 190.1 DNAJC19 "Pam18, Tim14, TIMM14" ENSG00000205981 "DnaJ heat shock protein family (Hsp40) member C19" Q96DA6 3 180983709-180989774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone Cardiomyopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 471.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037782 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA037782: AB_10672611" "unprognostic (4.52e-2)" "unprognostic (3.55e-3)" "unprognostic (3.08e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-1)" "unprognostic (5.54e-2)" "unprognostic (1.39e-1)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "prognostic favorable (8.53e-5)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.14e-2)" "unprognostic (1.75e-1)" "unprognostic (4.66e-1)" "unprognostic (3.33e-1)" "unprognostic (4.20e-3)" 22.7 44.1 26.1 11.1 27.1 10.8 26.4 27.2 39.7 19.4 28.8 27.5 21.4 18.9 33.0 22.9 21.3 11.8 73.4 27.2 28.0 50.2 48.9 14.7 16.3 26.4 29.3 26.5 27.9 34.7 30.9 14.2 26.3 22.6 17.7 27.2 28.1 18.2 65.8 15.0 18.1 11.8 27.6 18.5 26.2 11.6 26.8 20.7 25.6 77.8 13.4 23.5 18.4 28.1 53.9 14.0 38.8 29.6 45.6 27.0 35.4 30.2 18.2 29.1 25.5 49.0 26.2 23.0 63.9 25.5 70.9 26.8 37.8 36.5 35.9 36.5 49.1 27.0 24.5 48.3 48.9 64.9 27.5 25.9 29.8 24.4 43.0 37.9 34.0 55.2 42.8 35.8 23.0 44.2 48.5 54.6 51.2 75.9 44.8 31.4 26.9 69.6 43.3 24.8 38.7 20.6 30.8 75.8 82.3 44.0 85.2 45.2 16.8 18.5 27.1 26.3 54.4 47.7 60.7 80.1 19.0 49.9 22.9 33.6 20.4 31.5 33.3 22.3 39.8 34.7 38.5 34.7 28.6 29.8 39.8 40.6 4.4 26.8 27.3 36.4 35.0 30.8 26.1 27.1 27.2 39.7 27.2 28.0 26.4 29.3 26.3 27.6 26.8 28.1 68.3 38.5 52.5 11.1 66.3 56.6 68.6 105.4 56.9 31.7 138.6 183.0 151.7 120.1 70.1 77.3 14.6 116.6 67.4 57.9 471.6 83.9 9.1 57.4 50.4 61.4 45.2 48.8 18.7 109.3 111.2 71.7 30.1 42.7 110.7 79.7 68.6 167.0 68.0 48.8 20.5 90.7 91.6 35.5 59.8 13.2 85.1 42.8 74.7 9.4 58.6 91.4 74.2 13.0 21.4 79.9 66.1 72.6 47.7 91.5 101.0 216.8 58.7 67.6 85.5 80.3 108.8 82.1 56.3 73.9 60.1 68.7 68.4 121.4 86.7 69.2 DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Approved Enhanced Vesicles,Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: AB_2676443" "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" 23.2 23.2 25.3 23.5 27.5 40.0 21.1 27.7 32.3 18.4 15.7 24.0 18.6 23.6 23.9 28.6 19.8 17.5 38.9 28.4 26.1 27.9 14.2 16.7 20.9 22.5 22.0 20.0 13.5 40.5 25.3 23.9 23.6 27.0 22.7 44.9 16.0 28.7 43.8 18.3 16.8 32.0 22.2 18.8 17.3 36.0 21.6 21.4 22.4 57.2 24.8 29.9 18.5 26.6 66.8 62.3 64.3 68.3 51.2 52.7 123.2 72.0 55.4 67.2 61.7 80.6 48.0 87.3 50.0 65.8 66.9 57.8 69.2 80.3 79.3 46.6 57.6 102.3 57.2 48.2 41.7 72.5 50.1 48.6 37.4 70.7 66.1 63.5 81.1 41.4 74.4 37.5 75.3 21.7 29.1 61.7 138.2 41.0 30.8 48.6 125.0 61.5 56.5 79.1 57.1 59.3 76.3 51.8 56.7 129.4 59.7 49.0 74.0 57.3 54.4 135.3 68.2 26.1 75.8 86.3 55.6 47.0 43.5 7.4 10.0 3.2 5.6 15.6 6.9 7.0 6.2 6.1 18.8 6.0 7.3 8.4 1.8 8.1 15.6 5.6 7.3 7.9 25.3 27.5 27.7 32.3 28.4 26.1 22.5 22.0 23.6 22.2 21.6 26.6 42.5 38.5 38.4 82.6 36.0 30.0 34.7 28.0 44.3 80.9 32.5 29.2 82.8 20.0 33.3 25.8 131.3 30.0 53.8 26.7 31.3 34.8 63.9 38.8 55.8 42.0 30.5 28.4 139.4 25.1 63.7 41.0 23.9 59.4 50.7 48.8 26.4 16.0 30.8 126.2 150.0 24.9 34.6 27.5 30.7 78.0 26.8 43.3 14.2 44.0 45.6 59.0 34.0 99.5 121.7 45.7 14.4 30.5 48.5 42.8 11.4 23.3 22.8 164.8 19.7 55.0 55.5 79.3 52.3 39.6 27.6 36.0 42.2 26.0 31.5 36.4 DPH3 "DELGIP, DELGIP1, DESR1, DPH3A, KTI11, MGC20197, ZCSL2" ENSG00000154813 "Diphthamide biosynthesis 3" Q96FX2 3 16257061-16264969 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035287 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA035287: AB_10604113" "unprognostic (2.49e-2)" "unprognostic (8.80e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "unprognostic (1.52e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (1.22e-1)" "unprognostic (2.83e-1)" "unprognostic (5.06e-2)" "unprognostic (5.83e-2)" "unprognostic (4.13e-1)" "unprognostic (5.90e-3)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (1.19e-2)" "unprognostic (6.44e-2)" 14.2 11.9 12.7 9.6 13.5 8.4 10.3 14.3 14.3 10.2 13.6 11.5 10.7 10.0 11.0 9.4 8.9 10.2 13.9 12.2 15.6 13.1 15.3 11.1 8.9 15.4 14.4 6.1 7.8 9.0 8.5 13.2 15.0 9.3 8.7 13.4 5.7 11.1 29.4 4.9 13.3 15.2 14.7 9.1 9.4 8.5 13.6 11.5 12.4 20.1 8.1 12.4 5.8 15.5 10.5 14.6 31.9 18.9 58.9 39.7 24.8 29.9 24.4 28.0 31.3 18.1 5.8 10.0 9.3 37.5 24.0 6.2 29.4 17.7 32.6 50.5 20.4 16.6 11.5 21.0 36.7 24.5 15.6 28.6 23.6 36.0 15.2 17.6 25.5 17.4 26.9 16.4 39.9 14.1 19.0 16.5 25.6 15.9 14.7 12.9 20.7 15.4 24.9 8.0 7.2 20.2 13.8 6.7 35.4 25.6 12.5 23.9 29.9 22.9 15.0 41.7 24.0 12.6 44.5 12.8 33.6 27.2 20.7 27.1 16.7 25.7 11.3 22.8 14.0 10.1 11.9 13.8 15.9 9.9 9.9 11.9 35.5 10.7 21.6 6.2 11.9 12.7 12.7 13.5 14.3 14.3 12.2 15.6 15.4 14.4 15.0 14.7 13.6 15.5 32.3 19.2 22.4 10.1 31.0 51.6 42.9 41.0 29.0 11.6 32.9 34.7 34.9 25.8 32.4 16.5 12.5 47.9 28.1 43.0 41.1 49.5 109.1 27.5 35.3 32.5 17.9 32.0 12.0 57.2 80.6 34.4 30.1 33.3 52.0 11.2 26.7 41.6 101.6 6.7 10.3 22.6 26.4 45.5 61.7 63.3 20.5 46.4 28.4 3.7 71.5 24.8 29.9 6.6 9.2 66.6 32.4 15.8 42.2 42.6 79.1 45.4 33.9 15.1 13.1 33.4 36.7 80.4 40.1 31.3 52.4 80.9 34.5 18.7 19.0 47.1 DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766125-43778977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 274.3;Late spermatids: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 9 "dendritic cells: 33.5;granulocytes: 11.0;monocytes: 29.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063616 Supported Nucleoplasm,Cytosol NA NA 1300000 "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA063616: AB_2685061" "unprognostic (1.52e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (1.04e-3)" "prognostic unfavorable (3.00e-4)" "unprognostic (4.83e-2)" "unprognostic (8.98e-2)" "unprognostic (5.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.40e-3)" "prognostic favorable (5.49e-5)" "unprognostic (2.67e-3)" "unprognostic (5.45e-2)" "unprognostic (1.94e-1)" "unprognostic (1.37e-2)" 39.8 43.2 63.6 21.6 67.1 9.9 32.7 57.2 91.0 32.4 59.6 96.1 27.8 49.2 31.1 48.4 33.6 33.4 194.8 69.0 65.4 72.0 108.1 50.2 14.3 64.2 64.3 18.2 48.6 47.0 33.1 31.4 64.4 57.7 26.0 30.8 31.8 72.9 261.9 24.6 38.7 62.9 58.5 40.7 57.5 24.5 65.6 6.2 30.5 213.7 13.0 63.1 33.6 64.3 32.3 57.1 21.5 23.1 61.1 32.7 18.3 23.8 56.4 54.4 65.1 55.4 21.1 4.9 36.7 44.7 112.4 27.3 33.7 29.3 56.9 11.1 25.6 16.2 25.9 45.4 74.5 2.0 16.1 30.5 51.5 42.0 36.2 59.0 38.5 15.9 14.7 5.4 64.2 23.1 8.5 8.4 9.9 45.5 41.1 10.5 64.5 12.1 75.8 33.3 12.0 21.6 27.9 18.3 71.8 58.8 82.2 44.7 40.4 61.1 41.5 87.9 40.1 28.5 40.4 1.2 72.4 22.6 20.8 11.0 29.3 6.4 1.5 15.0 2.7 2.6 2.4 1.9 33.5 2.4 1.9 1.7 7.0 1.7 20.6 13.8 1.6 11.4 63.6 67.1 57.2 91.0 69.0 65.4 64.2 64.3 64.4 58.5 65.6 64.3 23.1 25.6 21.2 6.5 9.2 22.4 47.6 17.6 10.8 17.2 20.3 21.3 274.3 54.3 17.9 42.3 25.0 16.3 9.5 36.9 41.1 47.8 88.6 18.8 16.6 33.8 36.4 11.6 18.1 58.9 21.8 25.9 42.8 25.0 38.7 6.1 25.4 108.8 86.6 20.2 15.5 19.9 24.4 49.1 52.0 160.5 14.6 47.2 10.6 15.9 53.9 16.8 4.1 8.5 13.8 56.5 32.3 26.4 8.0 46.2 57.7 87.6 21.1 17.3 32.9 24.1 28.4 3.3 5.0 16.0 28.8 45.0 6.3 15.1 18.0 42.6 DYNLL2 "Dlc2, DNCL1B, MGC17810, RSPH22" ENSG00000264364 "Dynein light chain LC8-type 2" Q96FJ2 17 58083419-58095542 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 455.4;Late spermatids: 892.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 1000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (7.22e-2)" "unprognostic (7.76e-2)" "unprognostic (3.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.93e-1)" "unprognostic (3.72e-2)" "unprognostic (6.78e-2)" "unprognostic (2.91e-2)" "unprognostic (1.68e-1)" "unprognostic (1.10e-2)" "prognostic favorable (5.26e-4)" "unprognostic (1.24e-1)" "prognostic favorable (1.12e-12)" "unprognostic (2.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.31e-1)" "unprognostic (7.02e-2)" 24.5 41.8 76.8 17.7 84.5 17.7 16.9 78.1 77.7 18.2 45.6 26.1 25.0 19.6 22.4 20.3 19.4 13.4 62.8 63.4 80.4 42.1 35.2 17.9 15.5 83.6 90.1 20.4 17.8 47.2 28.7 30.4 83.6 30.3 20.1 41.2 30.8 26.3 113.7 19.1 24.3 18.9 83.4 18.0 21.3 26.2 87.9 22.5 33.0 58.7 18.4 20.7 17.6 72.0 54.1 36.0 72.3 33.1 44.0 24.0 114.6 53.2 21.1 25.2 19.7 80.4 25.4 48.0 58.8 33.1 30.1 28.4 33.8 42.2 43.2 47.8 24.5 52.1 21.9 47.7 34.8 56.2 31.1 24.3 28.2 29.4 23.2 26.4 17.1 39.8 52.7 28.4 24.7 81.5 64.1 23.2 49.9 35.3 36.5 58.3 42.5 19.9 22.0 57.9 49.3 39.4 47.7 19.0 42.0 37.2 56.2 26.1 31.0 49.3 62.2 33.2 39.8 52.6 68.5 57.0 25.5 44.2 35.2 1.0 0.2 0.5 0.6 0.1 0.7 0.4 0.5 0.6 0.1 0.4 0.5 0.8 0.4 0.4 0.9 0.2 0.4 0.2 76.8 84.5 78.1 77.7 63.4 80.4 83.6 90.1 83.6 83.4 87.9 72.0 33.9 12.8 43.8 1.0 28.1 49.1 40.7 13.7 45.5 63.7 55.7 39.8 186.2 44.3 23.8 60.7 39.6 102.1 59.7 56.7 31.3 37.6 455.4 51.5 57.3 32.5 67.2 40.6 1.2 31.2 73.4 30.6 20.9 55.2 22.8 19.1 23.9 104.7 43.0 70.7 2.0 55.7 26.4 28.4 37.4 892.8 29.5 32.8 65.8 1.9 31.9 74.7 19.6 0.5 2.8 38.0 38.6 26.7 19.4 35.3 50.0 78.2 18.4 41.1 26.3 40.1 86.1 46.5 44.8 45.1 46.0 60.1 46.9 29.0 49.7 36.5 EID2 "CRI2, EID-2, MGC20452" ENSG00000176396 "EP300 interacting inhibitor of differentiation 2" Q8N6I1 19 39538707-39540161 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045477 Uncertain Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA045477: AB_10959785" "unprognostic (5.91e-2)" "unprognostic (6.37e-3)" "prognostic favorable (9.73e-4)" "unprognostic (5.93e-2)" "unprognostic (6.50e-2)" "unprognostic (1.39e-1)" "unprognostic (2.52e-2)" "unprognostic (6.53e-2)" "unprognostic (6.02e-2)" "unprognostic (3.43e-1)" "unprognostic (6.88e-3)" "prognostic unfavorable (8.74e-4)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-2)" "unprognostic (1.55e-1)" "unprognostic (1.51e-1)" 10.5 17.9 13.3 8.8 14.5 6.4 8.5 13.3 19.5 7.7 11.9 9.1 6.8 11.0 8.1 9.2 8.4 6.2 10.1 14.3 15.6 12.6 10.8 8.4 9.1 13.8 11.8 8.4 7.8 12.6 13.0 14.3 14.1 9.0 6.6 15.7 7.7 8.0 11.1 7.4 9.0 9.8 12.5 9.5 8.8 9.0 12.8 14.2 8.3 10.4 8.4 7.8 6.5 12.6 25.0 33.4 31.1 21.2 24.7 15.3 4.6 29.3 22.0 22.5 23.2 21.2 7.7 25.4 23.5 20.6 15.1 10.5 29.0 21.3 29.0 24.6 36.5 11.4 19.1 25.5 24.5 19.9 16.1 18.0 13.3 18.7 14.4 17.8 26.6 49.0 18.8 17.2 19.8 16.5 29.0 17.5 17.4 30.1 14.0 26.6 29.7 11.9 28.9 22.8 29.0 20.6 31.8 12.6 21.0 20.9 17.1 12.9 19.2 14.3 51.0 19.1 22.3 26.9 33.8 32.1 13.3 18.5 11.8 0.0 0.4 0.7 0.8 0.5 0.8 0.5 1.0 1.0 0.5 0.5 1.0 1.4 0.1 0.3 0.5 0.5 0.2 0.4 13.3 14.5 13.3 19.5 14.3 15.6 13.8 11.8 14.1 12.5 12.8 12.6 16.4 19.2 9.2 2.6 7.3 10.1 4.5 2.4 6.2 23.9 11.2 15.6 19.1 17.2 4.0 14.7 10.4 48.9 14.0 6.5 1.9 5.2 3.2 18.3 23.3 14.4 7.2 4.2 7.4 5.0 5.3 10.0 5.1 12.4 1.3 14.4 13.2 12.9 10.8 26.9 8.0 5.3 0.0 8.1 6.5 1.3 10.2 7.8 8.8 3.7 7.5 31.1 12.3 5.0 8.6 6.2 7.4 13.2 7.2 5.3 5.9 9.5 5.5 20.7 6.6 9.7 12.7 11.3 8.8 5.2 7.5 19.4 11.3 25.2 7.5 2.6 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337371-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" NA Yes 210000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: AB_2676843" "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favorable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 39.4 31.6 50.3 32.8 53.5 20.8 33.9 50.8 88.8 31.3 51.1 56.3 23.1 35.2 41.7 44.4 29.6 18.5 89.6 48.8 55.3 50.9 38.4 30.9 32.6 54.1 52.5 27.0 48.6 32.1 28.2 29.6 55.0 44.0 30.0 23.8 36.5 33.5 102.9 39.4 29.1 28.7 52.8 30.7 42.1 48.6 53.6 26.2 29.3 56.2 36.6 47.8 33.7 53.0 117.0 57.2 63.8 83.5 75.5 88.7 105.4 100.4 62.9 65.3 64.6 132.5 80.9 132.5 84.6 75.2 77.4 64.9 112.6 97.3 114.6 80.8 67.4 159.6 57.7 175.9 59.7 158.0 94.3 60.2 66.8 91.0 92.1 55.9 96.6 80.0 179.6 64.4 95.2 94.9 100.8 145.7 99.5 76.2 83.0 86.8 94.7 108.2 134.9 96.2 53.8 50.9 54.6 123.8 85.3 120.4 50.5 103.0 106.9 100.7 99.3 53.2 90.7 47.4 72.0 106.0 73.3 172.0 75.9 19.8 11.0 13.7 15.5 12.5 18.2 20.9 16.3 15.5 8.4 19.8 15.9 17.0 2.9 18.3 17.3 26.2 12.5 6.4 50.3 53.5 50.8 88.8 48.8 55.3 54.1 52.5 55.0 52.8 53.6 53.0 121.7 109.0 219.6 23.8 152.4 321.3 200.4 209.0 84.8 103.8 159.1 112.1 579.1 135.8 198.6 343.9 50.1 143.7 142.9 135.0 144.8 210.5 769.9 143.1 175.0 153.2 157.9 154.2 27.4 235.1 205.3 130.4 82.0 157.5 172.7 90.0 146.3 480.9 134.7 77.4 28.3 206.7 144.5 123.5 128.9 144.0 124.5 95.7 142.3 18.7 157.7 91.8 145.2 21.6 36.7 282.6 93.8 175.7 183.2 253.9 102.7 226.2 165.4 111.3 276.1 167.3 157.7 575.3 505.0 99.1 324.8 181.4 133.4 101.7 185.1 244.7 ELOB "SIII, TCEB2" ENSG00000103363 "Elongin B" Q15370 16 2771414-2777280 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1279.6;Exocrine glandular cells: 911.2;Pancreatic endocrine cells: 1027.1;Proximal tubular cells: 1789.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064006 Approved NA NA 82000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "HPA064006: " "unprognostic (1.77e-1)" "unprognostic (5.27e-3)" "unprognostic (3.93e-1)" "unprognostic (1.50e-3)" "unprognostic (2.02e-1)" "unprognostic (2.28e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-1)" "unprognostic (1.81e-2)" "unprognostic (4.05e-2)" "unprognostic (3.14e-1)" "unprognostic (7.15e-2)" "unprognostic (7.83e-2)" "unprognostic (3.42e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (6.32e-2)" 234.7 293.3 355.3 130.9 359.6 289.7 235.0 363.3 479.4 217.1 339.1 275.5 141.6 214.1 80.8 297.1 217.7 180.2 485.0 365.8 363.9 301.6 340.1 206.6 185.6 356.8 360.3 187.8 207.5 203.4 279.9 109.8 358.2 233.8 83.2 51.4 332.2 112.9 573.1 254.5 203.5 89.5 362.8 208.8 255.6 428.5 366.5 154.6 199.4 266.2 93.4 220.1 228.6 367.5 185.8 559.0 254.5 407.0 263.5 354.6 265.7 233.1 242.6 254.3 210.0 408.8 372.6 288.6 309.4 256.7 275.1 206.6 146.4 403.4 61.9 349.4 593.0 188.5 773.6 578.7 410.1 276.9 286.6 362.8 517.3 242.4 180.6 254.7 225.8 420.1 258.4 465.0 265.5 1212.8 459.7 708.6 331.4 363.2 570.0 487.9 248.3 636.9 311.8 404.2 461.4 335.2 310.0 472.3 320.1 79.0 434.1 506.3 303.5 323.4 308.9 232.4 277.7 382.8 503.1 619.8 152.5 279.6 347.2 3022.8 1566.1 2928.2 711.2 1154.9 687.1 877.6 741.7 760.1 951.3 757.8 638.9 671.0 1519.2 892.1 1236.0 848.6 1046.2 2212.0 355.3 359.6 363.3 479.4 365.8 363.9 356.8 360.3 358.2 362.8 366.5 367.5 401.9 182.7 218.4 0.0 89.7 0.0 0.0 0.0 0.0 0.0 633.1 738.0 0.0 0.0 131.8 505.8 0.0 562.9 243.1 0.0 1279.6 752.8 0.0 641.0 734.0 188.1 0.0 0.0 0.0 911.2 689.1 219.6 0.0 551.8 107.2 339.5 0.0 0.0 719.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 304.4 0.0 0.0 419.2 0.0 0.0 0.0 0.0 1027.1 0.0 0.0 46.1 0.0 0.0 1789.2 241.9 0.0 0.0 0.0 233.3 0.0 0.0 0.0 0.0 496.8 132.1 310.6 0.0 0.0 ELOC "SIII, TCEB1" ENSG00000154582 "Elongin C" Q15369 8 73939169-73972287 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 266.1;Extravillous trophoblasts: 326.2;Hofbauer cells: 313.7;Pancreatic endocrine cells: 317.3;Proximal tubular cells: 341.3;Syncytiotrophoblasts: 332.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078113 Approved "Nucleoli,Vesicles,Cell Junctions" NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cell Junctions" "HPA078113: AB_2686877" "prognostic unfavorable (6.48e-4)" "unprognostic (1.60e-1)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" "unprognostic (2.46e-2)" "unprognostic (8.02e-3)" "unprognostic (5.84e-3)" "unprognostic (2.19e-2)" "unprognostic (1.77e-1)" "unprognostic (6.99e-3)" "unprognostic (4.02e-3)" "unprognostic (3.33e-2)" "unprognostic (2.77e-3)" "unprognostic (3.84e-2)" "unprognostic (5.33e-2)" "unprognostic (1.67e-1)" "unprognostic (8.95e-2)" 78.3 83.9 86.5 45.0 89.6 93.1 59.9 88.6 116.1 47.9 79.8 61.3 30.2 48.1 67.0 75.3 46.2 39.3 141.0 92.5 85.3 97.2 76.0 62.0 52.5 83.6 83.9 46.1 41.1 58.5 57.2 56.0 83.9 45.2 44.8 69.4 46.7 43.7 190.3 48.4 40.7 54.8 84.2 48.2 57.3 111.2 85.1 64.4 43.3 125.6 65.7 69.3 52.0 89.5 211.2 169.2 151.1 110.2 113.0 146.7 108.1 203.6 165.3 194.8 199.0 151.1 178.2 106.3 160.7 181.9 263.4 147.2 168.7 203.6 256.8 123.2 141.5 185.7 174.2 243.0 147.3 120.4 133.6 149.4 159.9 177.0 226.8 144.2 184.8 180.2 166.2 137.8 260.2 155.9 311.7 214.9 137.5 341.9 271.8 111.9 95.1 100.8 216.2 181.9 142.1 134.3 85.2 458.9 202.4 155.1 169.2 127.9 142.2 140.1 160.6 156.1 208.1 155.6 204.5 198.9 169.6 130.2 175.0 138.6 66.4 85.6 62.0 78.6 68.3 83.1 74.2 70.8 73.6 73.9 66.5 67.5 79.8 73.4 77.3 118.4 99.1 60.0 86.5 89.6 88.6 116.1 92.5 85.3 83.6 83.9 83.9 84.2 85.1 89.5 236.0 67.3 98.9 0.0 24.8 0.0 0.0 0.0 0.0 0.0 147.6 185.4 0.0 0.0 49.5 119.5 0.0 220.1 74.5 0.0 266.1 216.7 0.0 147.9 98.9 77.1 0.0 0.0 0.0 227.2 326.2 66.0 0.0 168.8 69.4 65.9 0.0 0.0 313.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.9 0.0 0.0 112.7 0.0 0.0 0.0 0.0 317.3 0.0 0.0 12.1 0.0 0.0 341.3 63.4 0.0 0.0 0.0 78.2 0.0 0.0 0.0 0.0 332.5 40.7 98.8 0.0 0.0 EMC10 "C19orf63, HSM1, HSS1, INM02" ENSG00000161671 "ER membrane protein complex subunit 10" Q5UCC4 19 50476400-50490871 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 185.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 193.0;PC-3: 137.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053905, HPA062723" Approved "Secreted to blood" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA053905: AB_2682303, HPA062723: " "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (9.86e-3)" "unprognostic (1.65e-1)" "unprognostic (6.94e-2)" "unprognostic (8.38e-3)" "unprognostic (3.23e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-1)" "unprognostic (2.99e-1)" "prognostic favorable (4.39e-4)" "unprognostic (5.01e-2)" "prognostic favorable (6.64e-6)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" 24.3 63.9 29.1 11.4 41.5 19.7 27.6 38.4 38.2 34.1 46.7 36.1 23.8 38.8 15.3 36.0 32.0 13.5 50.7 27.2 29.4 76.3 63.0 32.1 9.7 38.8 35.0 49.6 55.2 44.3 106.4 9.5 36.0 38.3 7.1 8.7 55.7 16.9 185.8 31.7 36.0 6.6 32.7 27.8 47.8 45.6 36.0 6.9 82.4 9.0 6.8 31.0 27.3 49.5 66.2 80.1 3.0 30.8 8.8 10.8 0.8 62.9 11.4 5.4 5.9 0.7 44.4 21.6 0.8 11.3 9.9 55.1 3.7 10.3 2.0 84.2 193.0 4.6 33.9 0.0 14.7 19.1 123.2 13.3 11.3 5.6 4.3 5.2 13.5 18.5 42.7 44.9 11.3 46.0 30.3 0.6 0.3 26.0 137.6 51.7 9.7 71.7 25.0 59.2 48.5 107.9 92.5 29.6 36.1 3.6 31.0 34.8 26.2 3.8 83.1 23.0 34.4 49.5 132.7 17.9 24.8 13.2 30.8 6.2 6.9 8.1 5.0 5.6 4.3 6.4 5.3 5.3 5.3 8.5 6.2 6.0 3.0 3.1 4.3 7.0 4.7 5.2 29.1 41.5 38.4 38.2 27.2 29.4 38.8 35.0 36.0 32.7 36.0 49.5 30.3 64.1 111.1 15.7 65.6 29.7 53.4 60.9 31.3 82.3 72.5 53.8 11.3 81.5 64.0 69.9 81.3 129.5 71.0 103.6 23.5 181.8 177.7 52.1 49.4 46.0 212.2 21.7 7.9 112.3 155.0 46.6 71.9 79.8 53.2 80.3 55.6 79.4 133.8 37.0 11.8 117.7 59.0 109.2 36.7 39.1 69.0 67.7 83.6 9.4 103.1 101.2 90.6 44.2 78.3 114.4 144.9 115.1 80.2 66.4 158.2 66.8 28.6 71.7 6.6 93.3 43.7 18.0 56.2 50.3 31.3 151.0 67.4 78.5 130.5 66.5 EMC6 "MGC2963, RAB5IFL, TMEM93" ENSG00000127774 "ER membrane protein complex subunit 6" Q9BV81 17 3668812-3669668 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 185.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062681 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Centrosome Nucleoplasm "HPA062681: AB_2684831" "unprognostic (2.21e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.21e-2)" "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" "unprognostic (6.20e-3)" "unprognostic (4.03e-2)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (7.58e-3)" "unprognostic (4.17e-2)" "unprognostic (1.94e-1)" "unprognostic (6.37e-2)" "unprognostic (3.27e-1)" "unprognostic (6.32e-2)" 35.6 58.2 35.1 14.7 36.0 30.3 31.4 38.9 40.2 24.7 40.1 40.8 20.0 29.1 11.3 49.3 27.0 5.2 91.0 34.8 37.2 53.2 75.8 29.2 13.3 36.2 35.3 23.4 44.3 18.5 27.7 13.5 35.9 33.0 10.3 17.2 35.5 10.6 185.0 36.9 35.3 9.0 38.5 37.8 47.4 63.3 37.3 15.5 29.6 60.7 12.6 32.8 30.4 37.8 92.8 88.6 38.1 40.1 26.9 21.4 73.2 64.7 31.4 51.7 47.5 54.1 33.8 57.6 91.6 30.3 45.9 87.2 44.5 45.6 37.2 56.0 166.2 41.9 65.4 76.2 38.7 29.3 41.6 27.1 50.6 47.8 33.2 40.9 39.8 68.0 53.4 40.6 38.6 56.2 60.5 86.2 55.0 55.9 99.1 55.7 35.5 55.3 74.2 25.9 31.3 56.7 53.1 41.2 75.6 37.8 48.0 31.1 44.2 43.3 54.4 65.9 96.5 39.5 47.1 38.4 67.7 38.0 53.3 91.6 83.1 87.1 66.1 83.8 61.1 74.6 73.6 73.4 72.7 72.0 75.2 68.5 62.8 56.5 60.7 114.3 92.5 87.4 35.1 36.0 38.9 40.2 34.8 37.2 36.2 35.3 35.9 38.5 37.3 37.8 40.1 16.0 25.9 9.4 60.3 89.0 127.1 144.2 42.1 41.8 82.9 87.8 0.2 82.9 74.8 58.8 35.5 118.4 68.1 55.7 166.3 126.2 252.2 90.0 42.7 56.6 51.4 46.7 7.4 142.8 148.6 40.8 48.4 58.0 55.2 59.8 47.5 148.7 102.5 33.7 8.4 74.7 105.8 57.1 49.6 176.1 38.5 56.6 67.6 3.7 83.3 125.9 77.2 5.5 17.9 164.8 71.6 34.3 81.9 179.9 84.6 203.8 82.2 52.9 39.5 43.3 111.7 151.0 91.6 81.1 101.9 129.0 52.7 65.0 72.6 169.5 EMC7 "C11orf3, C15orf24" ENSG00000134153 "ER membrane protein complex subunit 7" Q9NPA0 15 34084017-34101862 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010029 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA010029: AB_1078335" "unprognostic (2.16e-1)" "unprognostic (8.16e-3)" "unprognostic (5.28e-2)" "prognostic favorable (4.68e-5)" "unprognostic (7.75e-2)" "prognostic unfavorable (9.25e-5)" "unprognostic (1.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.18e-1)" "unprognostic (5.65e-3)" "unprognostic (4.67e-2)" "unprognostic (3.17e-1)" "unprognostic (1.36e-1)" "unprognostic (3.31e-1)" "unprognostic (2.58e-1)" "unprognostic (2.49e-2)" "unprognostic (2.47e-3)" 65.4 86.5 74.2 48.3 78.2 75.2 58.5 82.6 92.9 47.2 91.4 61.3 52.1 49.6 104.4 47.6 45.9 50.4 70.4 74.1 85.7 90.7 103.8 54.4 43.8 78.5 79.2 43.1 79.1 93.2 54.7 77.3 79.7 62.2 64.8 67.2 59.9 57.0 91.0 56.0 46.8 58.8 82.1 42.5 57.7 76.9 79.6 40.1 71.0 70.9 46.2 63.0 44.0 87.0 68.1 185.7 62.2 84.2 249.3 143.3 69.3 190.4 199.3 174.8 181.0 170.6 79.7 40.4 187.4 189.5 181.3 128.9 94.7 96.3 128.5 99.7 96.5 99.4 273.6 147.3 229.1 101.2 135.0 155.1 181.5 125.0 178.7 117.3 110.3 75.9 99.5 259.9 170.7 79.8 54.5 115.2 58.1 157.2 122.3 69.5 76.2 140.3 187.3 119.1 107.2 78.2 114.0 151.8 97.7 75.5 110.0 161.2 94.9 185.8 71.6 123.7 144.4 172.4 219.7 86.2 187.8 153.3 154.8 316.0 161.1 178.1 139.7 184.2 136.9 137.0 138.6 144.0 150.6 102.9 100.4 124.1 143.8 122.7 206.2 242.6 195.8 196.4 74.2 78.2 82.6 92.9 74.1 85.7 78.5 79.2 79.7 82.1 79.6 87.0 65.5 28.9 36.1 20.2 51.7 86.9 56.8 194.6 40.9 58.6 44.0 50.3 92.9 54.3 117.9 103.0 45.9 127.5 92.1 56.5 39.2 124.4 117.3 52.4 66.2 67.3 45.6 48.0 15.5 172.4 153.4 90.1 32.6 52.6 45.1 40.2 60.3 78.6 112.6 30.3 17.8 57.6 146.5 65.2 60.1 81.6 90.1 61.2 103.2 12.2 70.9 112.4 40.2 17.6 27.7 137.9 63.0 104.2 97.1 61.3 72.5 90.8 94.5 62.9 118.3 65.4 136.5 257.9 57.4 43.1 86.4 160.1 65.8 100.4 61.3 55.2 EMC8 "C16orf2, C16orf4, COX4NB, FAM158B, NOC4" ENSG00000131148 "ER membrane protein complex subunit 8" O43402 16 85771758-85799608 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 230.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049476 Approved Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Endoplasmic reticulum" "Golgi apparatus" "HPA049476: AB_2680784" "unprognostic (2.69e-1)" "unprognostic (2.62e-2)" "unprognostic (4.21e-1)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.49e-4)" "unprognostic (1.30e-1)" "unprognostic (2.41e-1)" "unprognostic (2.67e-3)" "unprognostic (1.03e-1)" "unprognostic (6.91e-3)" "prognostic favorable (6.39e-4)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" 13.5 12.9 13.9 8.3 14.7 17.4 12.7 14.7 13.6 9.7 13.2 12.5 10.6 12.7 7.2 13.1 9.2 6.3 19.5 13.9 13.9 13.8 12.8 9.3 10.1 14.8 14.3 8.2 10.9 11.0 10.2 9.3 13.8 9.9 8.7 7.1 9.9 8.7 20.8 10.5 10.5 9.3 15.1 10.9 11.7 12.2 14.8 10.3 9.6 12.5 9.5 11.7 9.4 16.0 29.8 34.1 21.3 19.5 22.6 21.6 41.4 28.7 28.4 46.9 20.8 54.7 33.5 25.6 32.5 29.1 21.0 33.3 32.0 30.1 41.5 10.9 45.7 21.1 17.3 50.3 34.2 21.7 13.7 23.8 20.1 35.7 41.5 20.2 27.1 30.9 48.6 9.6 29.2 50.7 34.5 61.4 42.5 27.4 43.3 50.0 17.4 21.8 29.9 20.7 35.9 21.4 52.8 17.1 33.9 18.9 33.9 38.1 23.8 28.1 28.7 24.9 37.1 26.6 27.3 102.8 24.1 41.3 30.2 17.9 18.1 25.6 10.9 19.2 12.7 11.1 11.8 14.8 24.2 15.6 14.7 14.4 7.5 19.2 19.5 17.8 12.3 12.3 13.9 14.7 14.7 13.6 13.9 13.9 14.8 14.3 13.8 15.1 14.8 16.0 60.1 6.4 8.6 10.4 25.0 61.3 30.1 28.9 25.0 33.7 26.7 26.0 19.9 15.7 18.5 25.8 12.5 48.5 25.0 28.8 60.7 46.9 230.2 37.1 28.3 33.6 46.6 21.5 6.1 42.1 60.7 26.2 18.8 40.9 9.5 25.1 23.6 23.3 47.0 15.2 7.8 27.4 26.4 28.0 38.0 55.0 24.8 27.1 28.4 8.4 41.9 27.8 27.8 8.0 12.2 50.0 27.2 31.6 33.3 51.1 29.1 46.5 12.5 18.6 26.3 22.5 28.9 54.2 56.5 33.5 54.6 51.0 22.4 37.0 35.6 41.9 EPS15L1 eps15R ENSG00000127527 "Epidermal growth factor receptor pathway substrate 15 like 1" Q9UBC2 19 16355239-16472085 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019237, HPA055309" Approved Approved Vesicles NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA019237: AB_1848223, HPA055309: AB_2682780" "unprognostic (3.06e-2)" "unprognostic (3.33e-3)" "unprognostic (2.19e-1)" "unprognostic (6.45e-3)" "unprognostic (1.35e-1)" "unprognostic (8.64e-2)" "unprognostic (2.58e-3)" "unprognostic (5.12e-2)" "unprognostic (1.07e-3)" "unprognostic (7.54e-2)" "unprognostic (5.21e-2)" "unprognostic (1.81e-2)" "prognostic favorable (8.10e-5)" "unprognostic (2.47e-1)" "unprognostic (9.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.32e-1)" 15.3 17.6 33.4 11.8 32.4 23.6 14.2 39.6 40.5 22.4 21.5 17.0 8.3 18.1 5.9 25.2 18.7 9.6 42.4 35.6 29.1 20.5 17.9 14.6 13.9 29.3 33.4 19.1 15.5 18.2 22.6 13.9 30.8 19.5 9.2 14.0 14.9 12.9 67.6 23.3 14.3 14.1 23.5 19.8 16.8 22.9 41.0 11.8 17.5 25.7 13.0 17.6 19.7 27.6 27.3 12.8 25.8 20.4 27.4 21.1 40.3 17.8 14.9 28.8 25.1 15.3 18.2 29.2 30.4 26.1 22.8 26.6 36.3 20.8 25.1 15.8 36.8 24.7 17.4 29.8 27.7 22.8 26.7 17.6 21.1 31.9 22.3 28.6 23.6 24.5 20.1 31.2 24.5 53.9 25.4 32.5 17.7 36.4 41.7 32.2 12.5 24.3 19.8 27.9 23.3 15.3 18.6 17.5 17.7 19.2 58.3 21.3 24.5 18.2 12.2 57.3 31.4 8.8 19.4 27.7 20.2 31.9 24.5 53.5 11.9 35.9 11.1 12.0 10.5 20.8 9.8 12.0 9.2 19.3 10.1 7.8 56.2 19.1 14.4 8.6 10.7 9.0 33.4 32.4 39.6 40.5 35.6 29.1 29.3 33.4 30.8 23.5 41.0 27.6 10.8 9.6 9.8 62.3 22.1 16.6 14.0 12.0 12.0 30.7 9.5 8.1 20.4 7.2 10.9 9.2 50.1 21.7 30.8 11.7 9.8 11.0 74.9 10.7 13.0 11.8 11.3 13.9 49.7 5.7 19.7 16.0 16.3 12.1 12.0 22.3 11.0 8.2 20.0 11.8 63.4 10.7 24.4 10.6 14.8 15.1 18.6 13.8 3.6 30.9 13.0 9.9 34.0 36.2 35.6 9.3 9.1 20.3 18.7 15.0 9.0 12.9 14.7 25.9 19.7 20.3 13.9 18.5 16.7 22.3 24.4 10.9 15.8 18.7 9.8 22.2 ERAL1 HERA-B ENSG00000132591 "Era like 12S mitochondrial rRNA chaperone 1" O75616 17 28855010-28861061 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021425, HPA024423" Supported Enhanced Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Mitochondria Cytosol "HPA021425: AB_1848228, HPA024423: AB_1848229" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "unprognostic (5.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.55e-1)" "unprognostic (8.37e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (8.20e-2)" "unprognostic (7.04e-2)" "unprognostic (2.70e-1)" "unprognostic (8.57e-3)" "unprognostic (5.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (2.49e-1)" "unprognostic (2.62e-1)" "unprognostic (5.79e-2)" 20.3 32.5 47.6 17.5 47.7 18.5 23.4 48.4 61.7 20.9 44.7 25.8 22.0 22.1 22.7 28.8 26.2 15.1 41.0 48.0 48.0 29.2 41.2 18.3 22.0 47.9 47.3 25.6 23.6 36.2 18.9 24.5 48.1 21.0 28.1 16.9 22.6 23.9 52.7 26.3 19.9 26.5 47.7 21.0 26.3 17.9 48.4 23.8 19.2 51.8 29.6 22.1 20.6 48.9 50.4 96.2 55.9 63.1 59.1 40.6 53.4 40.1 56.2 117.1 95.9 94.5 31.7 64.1 47.0 68.8 87.9 55.2 102.0 90.0 97.5 63.6 119.8 52.2 60.6 95.8 75.5 63.0 45.7 53.5 78.1 95.3 89.3 46.1 97.2 80.4 104.4 39.9 66.4 78.7 66.1 98.4 50.6 91.8 46.0 59.7 87.6 83.4 71.3 56.1 58.6 47.1 64.5 155.6 51.6 82.2 110.0 71.8 39.7 48.1 53.1 52.9 84.6 32.0 62.3 69.9 51.4 54.4 49.1 25.5 34.2 14.4 32.2 44.6 24.2 38.9 26.9 23.5 54.9 36.3 30.8 32.2 2.6 42.8 31.6 28.7 32.1 30.8 47.6 47.7 48.4 61.7 48.0 48.0 47.9 47.3 48.1 47.7 48.4 48.9 12.4 6.4 2.8 5.9 14.0 8.0 12.7 33.9 12.0 10.9 14.9 18.3 8.0 17.2 13.9 11.0 6.2 69.1 9.9 13.4 37.2 28.1 1.0 11.1 14.0 14.4 21.6 20.4 7.2 21.6 55.2 15.8 19.9 13.3 5.1 24.8 14.3 21.7 35.6 11.8 7.8 15.0 26.4 8.5 6.7 5.4 14.3 12.4 10.6 3.7 66.6 16.4 9.2 5.5 4.3 21.1 12.9 15.8 29.2 15.1 20.0 33.3 9.7 9.0 19.7 11.0 15.6 22.3 21.7 25.4 11.6 51.7 10.4 25.0 26.6 9.9 ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 493.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1105.3;Proximal enterocytes: 710.7;Proximal tubular cells: 1118.7" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1693.9;OE19: 770.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" 159.1 171.5 121.1 44.0 134.4 70.2 115.3 134.8 145.5 55.7 123.0 97.6 136.3 48.9 16.9 140.7 53.3 62.7 387.8 112.8 120.6 144.5 493.6 50.4 58.2 129.8 124.8 55.2 81.9 106.3 73.1 39.0 125.7 55.2 41.2 24.1 172.2 37.9 280.7 79.0 129.7 31.7 119.9 64.5 90.0 53.6 132.4 81.4 70.3 280.3 36.9 65.6 69.0 137.0 118.9 304.3 41.3 113.9 129.4 150.4 65.6 82.4 61.0 63.5 63.1 257.3 192.1 121.5 80.2 129.8 33.8 104.0 83.3 171.1 19.2 182.0 323.3 98.1 188.9 1693.9 141.8 92.1 67.6 235.3 50.3 86.1 88.2 79.2 54.9 115.0 146.6 130.2 83.2 243.7 95.2 86.2 26.7 770.2 372.0 104.5 114.4 224.6 88.5 135.7 91.7 44.5 184.5 49.9 94.4 29.4 130.3 86.3 77.8 65.9 67.6 71.4 73.3 195.8 130.0 109.8 335.0 135.1 172.5 127.7 190.1 119.6 104.3 212.3 137.4 281.6 156.0 134.2 225.3 303.1 163.6 136.0 97.8 205.3 165.7 265.1 225.7 140.5 121.1 134.4 134.8 145.5 112.8 120.6 129.8 124.8 125.7 119.9 132.4 137.0 90.9 80.1 93.8 15.3 75.6 65.0 114.9 196.4 55.2 77.1 129.9 170.1 243.8 234.4 122.5 121.4 31.3 240.7 58.7 440.9 571.3 188.0 139.2 67.5 70.2 76.2 168.4 120.0 4.1 140.5 206.6 93.8 128.9 48.2 88.8 63.2 144.9 1105.3 217.5 43.7 4.2 335.2 158.7 147.7 73.4 354.4 107.5 86.9 286.4 5.6 95.2 158.8 50.4 7.1 18.9 155.4 339.4 114.3 69.9 74.9 710.7 1118.7 118.8 67.9 98.6 87.4 144.5 71.0 52.8 135.3 63.6 160.1 74.0 217.3 354.4 140.3 ETFRF1 LYRM5 ENSG00000205707 "Electron transfer flavoprotein regulatory factor 1" Q6IPR1 12 25195216-25209645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 305.2;Proximal tubular cells: 183.8;Theca cells: 69.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044255 Approved NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "HPA044255: AB_10967895" "prognostic favorable (9.63e-4)" "unprognostic (1.30e-1)" "unprognostic (2.01e-1)" "unprognostic (9.17e-2)" "unprognostic (5.96e-2)" "unprognostic (1.70e-1)" "unprognostic (3.57e-3)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (2.49e-2)" "unprognostic (3.41e-2)" "prognostic favorable (9.23e-5)" "unprognostic (1.55e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-3)" 28.2 46.3 43.9 13.5 48.3 12.9 35.0 49.5 69.8 25.7 41.2 17.9 33.4 19.6 35.6 22.5 18.3 22.5 53.1 43.4 47.4 55.9 121.3 21.7 17.9 50.0 46.4 20.6 24.1 37.2 15.1 17.5 49.5 26.4 19.4 30.4 30.4 20.6 89.1 24.2 23.9 18.3 49.7 18.3 30.3 56.3 45.8 18.9 43.2 101.5 16.5 18.1 12.0 57.0 13.4 12.6 16.8 11.1 25.4 40.4 12.1 14.7 21.4 15.1 17.4 6.0 15.0 4.3 10.2 23.4 9.6 9.4 14.2 14.9 17.0 15.9 12.1 21.5 13.8 7.9 27.3 19.4 12.1 26.1 48.9 13.8 23.5 46.5 23.9 23.9 25.5 13.5 24.1 14.1 16.9 50.1 26.8 29.6 16.1 11.2 19.8 26.2 40.8 10.4 17.3 12.2 13.4 14.1 40.2 42.5 21.7 27.1 14.0 6.0 8.1 33.1 9.2 16.6 10.9 16.6 26.2 15.2 18.7 24.9 8.5 7.8 8.5 9.5 12.1 21.3 15.2 11.6 8.9 16.8 27.7 22.6 15.6 17.1 6.2 13.3 7.7 12.3 43.9 48.3 49.5 69.8 43.4 47.4 50.0 46.4 49.5 49.7 45.8 57.0 38.0 19.2 24.4 0.0 10.6 0.0 0.0 0.0 0.0 0.0 39.1 48.8 0.0 0.0 9.3 27.6 0.0 56.2 11.9 0.0 305.2 31.0 0.0 36.8 17.0 13.8 0.0 0.0 0.0 45.8 19.2 12.1 0.0 36.1 11.4 14.2 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 25.6 0.0 0.0 3.0 0.0 0.0 183.8 4.4 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 65.5 9.0 69.1 0.0 0.0 FAM110B "C8orf72, MGC39325" ENSG00000169122 "Family with sequence similarity 110 member B" Q8TC76 8 57994509-58204279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Inhibitory neurons: 195.6;Oligodendrocyte precursor cells: 253.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 13.4;intermediate monocyte: 3.5;non-classical monocyte: 6.8" "Group enriched" "Detected in many" 11 "granulocytes: 13.4;monocytes: 6.8" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008318, HPA011781" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Mitochondria, Cytosol" "HPA008318: AB_1853892, HPA011781: AB_1853891" "unprognostic (2.07e-1)" "unprognostic (6.91e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.88e-8)" "unprognostic (4.09e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (1.44e-1)" "unprognostic (2.02e-1)" "unprognostic (8.72e-2)" "prognostic favorable (1.44e-4)" "unprognostic (1.06e-2)" "prognostic favorable (4.31e-8)" "unprognostic (2.23e-3)" "unprognostic (1.97e-1)" "unprognostic (1.37e-1)" "unprognostic (1.15e-4)" 6.6 1.3 14.1 1.9 11.5 2.2 5.2 18.1 12.0 7.9 8.1 6.6 0.8 5.7 2.2 1.3 5.0 2.7 15.7 15.2 18.1 5.6 5.6 3.8 0.7 11.7 11.2 5.3 1.6 10.9 3.8 2.7 14.0 5.3 1.4 4.0 5.8 6.7 12.0 2.8 3.2 6.0 8.2 20.5 4.6 6.1 11.9 0.7 6.1 6.0 0.7 6.3 4.9 7.4 0.0 1.1 3.9 0.1 1.7 0.6 1.5 7.5 8.6 5.1 2.3 0.0 0.1 0.0 1.4 5.3 4.6 0.0 3.5 0.0 3.9 0.0 3.6 0.7 1.1 4.5 5.8 1.0 0.2 6.1 1.4 0.2 3.2 0.6 0.0 1.7 0.0 0.1 3.9 0.1 0.0 2.7 3.7 5.3 1.6 0.0 4.3 0.0 12.8 0.8 3.7 4.1 0.0 0.5 0.2 4.5 3.4 0.4 0.0 3.6 2.3 0.0 2.6 1.6 0.0 0.0 1.7 0.0 4.3 0.0 1.4 13.4 0.0 3.5 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.2 0.5 0.0 6.8 0.0 0.1 0.7 14.1 11.5 18.1 12.0 15.2 18.1 11.7 11.2 14.0 8.2 11.9 7.4 4.2 0.0 5.5 39.2 0.5 9.8 22.8 0.2 3.4 10.6 8.9 6.6 27.7 1.5 0.9 23.9 2.1 1.7 0.1 0.1 7.9 8.7 5.8 1.0 10.9 7.5 7.2 0.0 37.5 2.9 21.9 28.1 9.2 2.5 4.5 5.4 14.6 8.0 4.9 6.7 195.6 0.2 4.1 8.7 10.2 2.2 9.9 6.6 16.0 43.1 1.3 20.1 0.0 253.8 9.2 1.7 0.1 14.7 0.2 17.4 0.0 8.8 0.7 6.6 32.9 38.1 19.8 1.2 2.5 1.0 4.1 1.5 1.0 0.5 0.0 6.7 FAM118B FLJ21103 ENSG00000197798 "Family with sequence similarity 118 member B" Q9BPY3 11 126211724-126262984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041644, HPA042100" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041644: AB_10794303, HPA042100: AB_10795394" "unprognostic (8.11e-2)" "unprognostic (9.87e-3)" "unprognostic (4.05e-3)" "unprognostic (3.13e-2)" "unprognostic (9.55e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (6.67e-7)" "unprognostic (1.85e-2)" "unprognostic (3.03e-3)" "unprognostic (1.43e-1)" "unprognostic (7.12e-2)" "unprognostic (1.64e-1)" "unprognostic (3.76e-2)" "unprognostic (1.15e-1)" "unprognostic (9.49e-2)" "unprognostic (3.82e-1)" "unprognostic (7.44e-2)" 9.3 10.5 15.1 10.3 19.2 4.3 7.6 15.7 20.4 10.4 20.2 24.0 18.5 10.0 12.3 7.6 6.7 10.5 18.2 15.5 16.2 10.3 8.9 16.3 12.7 15.1 15.3 6.2 5.7 7.7 9.0 11.1 15.3 7.3 23.6 9.0 8.0 9.3 22.0 5.4 13.1 14.2 16.0 10.5 14.9 21.4 15.6 14.1 10.2 16.3 14.0 13.6 6.2 16.3 11.7 14.3 31.5 23.6 43.4 28.5 14.0 18.5 33.2 20.4 21.2 29.0 18.5 13.0 19.2 23.5 42.4 15.2 33.5 19.7 24.8 21.2 14.5 41.3 6.8 19.5 33.7 20.7 13.0 23.7 19.9 25.0 23.0 20.5 46.8 24.9 25.8 17.8 29.6 10.9 27.8 16.2 25.6 63.3 26.4 24.1 25.1 11.6 34.4 18.3 14.5 15.2 21.5 14.0 26.8 36.8 27.3 12.4 29.2 20.7 15.2 17.9 16.3 9.3 11.7 22.0 8.9 31.0 26.9 33.8 43.4 21.9 14.6 58.8 18.6 15.2 14.4 18.9 48.1 15.9 12.9 16.0 9.0 18.9 59.6 21.9 18.0 25.2 15.1 19.2 15.7 20.4 15.5 16.2 15.1 15.3 15.3 16.0 15.6 16.3 8.6 3.2 16.4 14.4 5.6 4.1 4.2 21.9 1.2 3.1 3.3 3.6 10.4 4.3 9.6 12.9 4.2 9.3 5.0 21.9 5.9 16.0 7.5 5.0 6.0 12.4 3.6 8.6 19.1 17.2 12.4 8.3 21.4 4.1 10.8 9.1 9.7 5.5 24.2 1.7 17.6 11.4 12.2 16.7 9.4 9.2 7.8 11.0 3.6 12.2 16.9 13.5 13.4 16.1 12.7 14.0 12.8 21.8 9.5 4.1 11.4 12.9 6.8 5.7 6.6 3.4 10.2 46.0 20.6 3.5 3.4 13.0 5.3 11.0 16.6 5.7 FAM166B ENSG00000215187 "Family with sequence similarity 166 member B" A8MTA8 9 35561831-35563899 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "adrenal gland: 270.0;fallopian tube: 83.1;skeletal muscle: 185.9" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 108.0;Respiratory ciliated cells: 126.4" "Group enriched" "Detected in many" 5 "endometrial cancer: 11.7;ovarian cancer: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045540 Enhanced NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA045540: AB_10962627" "unprognostic (4.18e-5)" "unprognostic (7.56e-3)" "unprognostic (1.65e-1)" "prognostic favorable (2.61e-5)" "unprognostic (5.66e-3)" "unprognostic (3.48e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-2)" "unprognostic (2.21e-1)" "prognostic favorable (6.20e-6)" "unprognostic (3.69e-3)" "unprognostic (9.09e-2)" "unprognostic (4.37e-3)" "unprognostic (5.82e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (3.52e-5)" 5.2 270.0 1.9 0.0 1.5 0.0 2.5 1.2 1.2 3.6 8.8 0.3 0.0 1.3 9.0 0.6 83.1 0.1 0.5 1.7 2.3 0.7 0.6 4.2 0.1 4.7 7.0 0.3 0.2 0.1 0.4 0.0 4.5 0.3 0.2 0.1 0.7 0.6 185.9 0.6 0.6 0.1 5.5 0.2 0.4 0.2 2.2 0.0 0.3 18.3 0.3 0.2 0.2 2.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.5 1.2 1.2 1.7 2.3 4.7 7.0 4.5 5.5 2.2 2.7 0.3 0.0 0.5 0.0 0.0 4.7 1.2 9.2 2.2 0.0 0.3 2.4 0.3 0.0 10.1 0.0 2.1 0.2 0.3 0.0 0.0 0.2 0.3 108.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.2 0.0 0.1 0.4 0.5 0.1 0.0 0.1 0.0 24.4 0.0 0.7 0.3 0.3 0.3 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 3.3 126.4 0.2 0.0 3.1 3.3 0.2 0.2 2.0 2.0 0.0 0.3 2.1 0.2 0.5 FAM174A "NS5ATP6, TMEM157, UNQ1912" ENSG00000174132 "Family with sequence similarity 174 member A" Q8TBP5 5 100535374-100586741 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 154.5;Respiratory ciliated cells: 222.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 55.8" "Lineage enriched" "Detected in all" 10 "granulocytes: 55.8" "Cell line enhanced" "Detected in all" "U-266/84: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019539 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" Cytosol "HPA019539: AB_2293743" "unprognostic (2.34e-1)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (9.02e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (5.55e-3)" "unprognostic (3.06e-1)" "unprognostic (2.60e-1)" "unprognostic (3.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.73e-2)" "unprognostic (7.69e-2)" "prognostic favorable (5.48e-4)" "unprognostic (1.74e-1)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" 16.1 23.1 13.0 8.1 14.4 2.8 15.3 13.4 16.5 11.4 23.3 12.6 11.2 12.1 12.1 24.3 34.8 7.5 19.5 13.8 18.6 17.3 15.7 17.2 5.6 13.9 14.0 10.1 22.6 29.3 27.4 15.1 14.9 18.2 8.5 16.8 17.4 11.8 42.8 30.3 10.3 8.0 13.9 10.2 15.5 22.0 14.6 5.3 13.6 24.7 5.4 13.0 16.9 14.6 10.3 10.7 4.3 13.6 10.3 8.4 15.1 23.1 12.9 9.3 12.7 2.2 13.1 1.8 46.2 10.1 16.2 8.6 3.6 15.1 7.0 12.8 10.9 1.3 18.6 6.4 13.9 5.3 12.4 10.7 35.4 7.2 5.5 21.3 14.3 5.3 3.8 13.7 15.9 20.7 1.6 11.1 2.4 1.2 29.1 3.6 16.2 18.2 17.0 12.3 8.6 23.4 16.2 14.5 13.7 5.0 13.9 11.5 16.1 11.7 7.4 19.0 18.5 44.3 61.5 2.4 14.5 7.1 10.4 7.9 4.9 7.1 3.3 5.5 5.1 2.8 3.3 4.0 4.4 3.3 2.9 3.8 55.8 5.5 5.7 4.4 4.4 3.3 13.0 14.4 13.4 16.5 13.8 18.6 13.9 14.0 14.9 13.9 14.6 14.6 40.8 32.1 31.8 13.1 13.8 88.1 31.4 80.3 43.3 29.7 57.3 31.2 17.4 34.3 54.7 29.5 4.2 44.5 10.0 17.8 43.0 30.6 33.2 154.5 13.8 27.1 34.8 20.6 26.0 30.0 40.3 26.9 18.8 25.3 13.3 8.1 35.0 30.6 23.5 30.3 38.3 32.3 85.5 16.8 22.1 10.1 18.0 14.1 49.8 15.9 17.1 75.4 6.2 19.1 25.1 30.2 23.3 24.5 60.7 28.1 23.2 40.0 222.5 42.3 13.1 48.7 24.3 91.5 20.7 59.6 115.1 50.3 13.8 18.4 18.9 43.1 FAM98A DKFZP564F0522 ENSG00000119812 "Family with sequence similarity 98 member A" Q8NCA5 2 33583660-33599382 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036250, HPA036251" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA036250: AB_2675020, HPA036251: AB_10673124" "unprognostic (7.25e-2)" "unprognostic (9.92e-2)" "unprognostic (1.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.86e-7)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (3.51e-1)" "unprognostic (2.02e-2)" "unprognostic (2.38e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (6.01e-2)" 29.2 21.5 21.4 20.5 26.5 7.2 16.3 28.6 30.4 21.7 27.9 20.7 13.6 19.1 19.3 19.9 12.2 15.7 40.6 30.8 25.7 27.4 25.5 11.5 18.4 25.1 24.5 16.5 14.6 51.2 20.5 20.6 29.5 23.0 17.1 17.2 28.0 16.7 61.3 14.9 12.1 36.4 27.7 14.3 19.8 49.4 26.4 17.4 19.2 62.4 22.6 27.5 12.9 39.7 93.4 47.2 25.5 43.9 99.4 108.3 41.9 224.1 81.6 62.3 80.2 49.8 18.8 144.5 41.3 101.8 55.3 41.3 84.8 60.8 84.2 67.7 56.3 119.7 46.9 69.3 47.2 95.5 44.7 56.1 42.2 83.9 52.1 63.5 83.3 15.5 84.4 43.8 108.7 46.1 53.3 28.5 64.4 83.2 59.9 41.1 82.5 51.9 65.0 72.2 45.6 26.1 60.0 89.5 27.0 40.7 36.2 15.6 135.7 39.5 66.1 82.9 89.2 80.2 106.6 142.4 91.2 68.2 56.8 1.3 4.1 2.3 6.4 7.2 6.9 10.7 5.4 5.8 6.1 5.5 6.9 5.7 0.1 4.0 4.6 3.5 9.0 4.1 21.4 26.5 28.6 30.4 30.8 25.7 25.1 24.5 29.5 27.7 26.4 39.7 19.0 22.4 11.5 6.8 17.4 20.4 19.0 12.2 18.8 16.8 15.0 14.0 74.6 11.5 19.8 7.3 2.1 25.5 9.8 6.9 25.4 20.3 14.9 16.7 29.9 21.1 5.4 12.8 22.8 29.2 33.2 31.9 17.9 18.9 2.5 44.4 17.2 23.4 16.4 47.1 15.7 15.1 8.2 7.7 11.8 13.8 22.4 8.7 8.8 6.5 5.9 17.4 16.5 9.0 36.1 26.0 8.7 21.8 40.3 22.6 9.3 46.2 16.5 15.7 0.0 21.7 27.1 41.5 40.1 26.1 20.5 40.0 13.7 54.9 12.1 23.4 FARSA "CML33, FARSL, FARSLA" ENSG00000179115 "Phenylalanyl-tRNA synthetase subunit alpha" Q9Y285 19 12922479-12934037 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001911 Enhanced Approved Cytosol NA NA 55000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA001911: AB_1848427" "unprognostic (1.52e-1)" "prognostic favorable (8.23e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (9.22e-4)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (4.93e-3)" "unprognostic (5.76e-2)" "unprognostic (2.86e-1)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (1.45e-3)" "prognostic favorable (8.32e-4)" "unprognostic (2.59e-1)" "unprognostic (8.25e-2)" "unprognostic (1.84e-2)" 26.4 32.5 30.1 29.4 32.2 31.6 25.0 28.1 40.0 21.8 19.4 29.1 26.2 24.3 12.1 39.2 24.0 16.4 37.4 33.4 32.7 29.1 40.6 20.7 36.0 32.6 31.8 23.1 36.3 30.4 32.1 22.5 33.4 25.5 17.1 14.7 30.4 21.7 57.0 33.3 26.5 17.7 24.3 32.0 30.6 22.6 30.6 33.0 25.5 30.6 25.4 30.6 25.6 31.1 135.7 125.6 49.3 106.9 33.4 31.4 88.9 93.6 60.8 133.0 103.9 154.2 56.1 148.7 147.1 54.1 53.9 101.9 121.0 108.4 48.1 87.9 183.7 117.0 106.8 124.2 108.4 227.7 147.8 43.4 78.7 102.8 82.1 43.8 73.1 148.7 179.6 30.6 56.7 181.5 273.4 283.5 154.2 83.4 210.6 139.5 51.2 191.4 70.5 78.7 153.8 141.4 64.2 109.2 69.0 23.0 85.9 137.5 71.3 108.0 47.8 165.6 180.6 199.6 186.5 156.8 97.7 203.4 114.1 66.6 111.0 86.3 87.1 119.0 108.2 88.2 85.1 81.4 120.4 94.5 85.4 82.3 7.0 118.0 92.8 97.0 87.6 130.2 30.1 32.2 28.1 40.0 33.4 32.7 32.6 31.8 33.4 24.3 30.6 31.1 15.0 9.6 21.4 9.1 24.7 25.4 28.0 63.4 20.5 25.1 18.8 18.5 25.7 14.3 35.4 23.9 10.4 87.5 17.5 26.7 58.7 55.4 5.8 16.0 18.6 20.0 22.8 61.8 12.1 46.4 78.7 18.4 27.5 15.8 23.5 26.3 21.0 25.8 62.9 18.5 12.8 32.6 69.2 23.5 21.2 9.4 19.0 19.7 33.8 1.9 45.5 23.6 25.7 8.5 7.5 47.0 26.3 13.2 40.9 32.6 30.4 55.7 22.3 17.1 6.6 16.5 24.3 20.2 41.9 26.3 29.5 96.7 22.5 28.9 44.7 26.8 FASTK FAST ENSG00000164896 "Fas activated serine/threonine kinase" Q14296 7 151076593-151080866 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031621, CAB032539" Approved Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nuclear speckles" "CAB032539: AB_2101115, HPA031621: AB_10611966" "unprognostic (7.67e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (4.73e-4)" "unprognostic (2.60e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-2)" "prognostic favorable (3.99e-4)" "unprognostic (3.49e-2)" "unprognostic (2.79e-2)" "unprognostic (4.12e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.17e-2)" 23.4 36.5 35.5 13.4 33.8 8.2 21.7 32.3 50.6 23.5 30.1 31.5 26.2 23.3 11.9 39.5 21.1 14.5 66.9 34.8 32.9 34.9 58.0 18.8 14.4 34.2 33.9 24.6 28.1 31.0 41.2 9.4 34.5 34.1 11.8 7.9 27.8 18.8 122.6 28.2 25.0 11.8 33.1 24.8 29.0 21.8 35.7 14.7 26.9 95.3 10.5 26.7 25.1 34.3 39.3 45.0 13.9 34.9 50.4 22.4 22.8 29.9 40.1 25.3 29.7 31.5 34.9 9.2 41.0 40.9 46.9 24.1 13.5 36.4 6.1 26.9 23.8 11.4 12.7 27.8 62.7 9.0 25.2 29.8 51.8 29.4 21.5 20.9 30.0 22.4 17.0 20.2 29.2 80.4 20.4 23.5 24.6 47.8 50.8 13.2 17.4 30.4 34.2 27.8 16.4 18.2 40.3 62.5 43.0 11.5 34.4 31.2 24.0 32.7 7.5 31.7 28.0 50.5 33.0 6.5 66.2 19.0 39.8 18.0 31.5 30.1 22.3 32.5 23.4 19.5 23.4 23.4 28.4 21.6 25.5 21.9 6.8 20.4 32.5 38.2 28.3 21.9 35.5 33.8 32.3 50.6 34.8 32.9 34.2 33.9 34.5 33.1 35.7 34.3 21.2 0.0 7.0 17.9 34.3 24.6 37.8 68.8 23.3 42.9 31.7 26.9 18.9 30.0 43.6 25.8 25.0 49.2 38.2 59.2 86.1 49.4 10.0 22.5 21.3 22.9 44.9 28.2 12.7 47.6 26.8 33.8 54.6 24.8 38.8 38.6 23.6 37.1 43.3 37.0 13.6 54.9 59.0 26.3 22.5 20.2 36.4 25.8 94.3 7.5 35.3 54.7 44.3 9.5 10.7 38.6 40.0 34.3 46.1 27.7 86.6 66.3 24.9 51.1 13.1 33.7 35.0 58.5 70.7 36.0 25.3 60.5 34.8 50.1 61.2 35.0 FBXL5 "FBL4, FBL5, FLR1" ENSG00000118564 "F-box and leucine rich repeat protein 5" Q9UKA1 4 15604381-15681679 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 252.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 407.0" "Group enriched" "Detected in all" 5 "dendritic cells: 108.2;granulocytes: 407.0;monocytes: 225.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002484 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002484: " "unprognostic (1.53e-1)" "unprognostic (8.08e-2)" "unprognostic (6.34e-3)" "unprognostic (1.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (2.18e-2)" "unprognostic (6.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.42e-2)" "unprognostic (3.70e-2)" "unprognostic (5.14e-2)" "prognostic favorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (5.39e-3)" "unprognostic (6.18e-2)" 72.8 50.9 49.0 40.2 53.9 110.9 51.9 56.3 65.5 53.8 50.3 51.3 29.8 42.1 63.5 43.0 46.1 51.6 49.5 48.1 51.2 128.0 77.4 48.8 35.3 49.9 52.6 41.5 32.7 59.4 44.4 37.1 50.1 51.5 36.2 48.0 36.9 56.4 80.1 36.3 31.7 55.1 50.9 45.1 41.5 68.0 52.2 46.3 70.6 85.5 32.6 53.9 37.7 55.2 23.3 17.8 42.3 23.9 65.0 63.9 13.4 30.4 37.2 32.7 45.9 14.3 34.1 18.1 14.2 36.4 57.8 8.5 21.9 36.5 50.3 17.7 11.2 17.8 12.9 16.9 65.3 21.7 16.4 59.0 48.4 30.4 46.9 74.9 86.8 15.7 15.2 14.8 99.1 10.5 41.3 33.4 22.3 19.1 15.8 29.5 43.0 14.8 51.8 32.9 20.4 19.2 28.4 10.0 32.8 57.7 16.2 35.8 20.8 37.8 10.7 26.0 38.0 20.1 22.2 16.8 32.4 37.7 46.6 204.3 225.4 115.2 46.2 112.9 44.9 33.5 42.5 44.7 108.2 31.3 44.0 44.8 407.0 42.4 101.7 16.6 40.6 206.8 49.0 53.9 56.3 65.5 48.1 51.2 49.9 52.6 50.1 50.9 52.2 55.2 37.0 44.8 62.0 63.6 31.3 27.3 37.2 40.5 62.0 52.3 34.6 28.2 88.1 41.5 46.9 36.8 6.2 53.3 38.9 24.4 78.2 29.2 80.3 32.5 41.2 42.5 25.9 29.9 73.6 23.3 41.8 47.0 36.2 42.1 39.9 38.6 40.0 69.1 48.5 40.4 78.7 20.1 32.6 109.9 28.4 52.9 39.7 81.1 30.2 63.7 138.4 36.2 44.3 65.9 120.2 18.8 20.4 58.3 39.1 30.8 37.2 252.3 61.9 41.1 59.2 42.1 46.2 188.5 73.5 63.1 26.1 26.4 45.4 38.4 25.6 32.7 FBXW11 "BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696" ENSG00000072803 "F-box and WD repeat domain containing 11" Q9UKB1 5 171861549-172006873 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072204 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "HPA072204: AB_2686493" "unprognostic (4.04e-3)" "unprognostic (1.27e-1)" "unprognostic (2.69e-2)" "unprognostic (5.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (6.87e-2)" "unprognostic (9.43e-2)" "unprognostic (1.53e-1)" "unprognostic (8.14e-3)" "unprognostic (2.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.54e-1)" "unprognostic (3.76e-3)" "unprognostic (1.76e-1)" 19.5 20.4 33.3 13.6 38.2 8.2 17.0 34.7 41.6 19.9 27.4 14.6 12.6 22.9 12.4 24.2 27.0 17.5 36.1 38.0 35.5 23.0 20.7 17.6 16.7 33.3 34.4 25.6 29.1 33.1 14.2 13.9 33.1 19.0 16.0 37.2 13.5 20.3 34.5 13.7 13.2 26.1 34.4 18.1 20.0 14.3 37.7 17.3 21.1 35.6 22.0 19.2 15.8 42.4 35.4 35.6 52.0 45.2 39.9 40.2 26.4 37.1 51.7 45.0 54.9 36.7 23.1 32.5 44.3 46.4 72.0 22.8 37.6 56.3 74.6 42.7 37.3 26.2 35.0 28.5 35.4 29.8 36.0 28.5 38.2 36.8 59.8 48.5 38.6 27.3 16.6 31.7 55.7 26.5 20.7 15.3 19.8 20.8 39.5 30.1 43.7 22.0 34.8 29.2 21.6 37.2 32.9 27.3 70.8 38.7 34.2 31.0 33.8 44.3 22.0 27.4 37.2 31.8 38.9 22.2 31.3 27.8 34.6 25.4 7.3 7.2 5.8 5.1 6.1 8.5 4.8 5.7 7.3 8.4 4.3 5.7 7.1 14.1 5.7 8.6 5.7 6.6 33.3 38.2 34.7 41.6 38.0 35.5 33.3 34.4 33.1 34.4 37.7 42.4 35.4 25.6 21.2 75.4 52.7 19.1 15.6 21.8 32.5 43.5 26.4 22.1 59.1 42.9 20.8 27.6 8.4 8.5 49.8 25.1 43.0 33.7 32.9 42.0 47.9 26.3 28.8 27.4 86.5 36.9 7.8 24.7 38.2 51.0 20.8 25.8 29.3 43.1 12.8 35.3 85.3 21.6 20.3 29.6 25.3 34.3 29.5 26.6 12.4 62.8 24.6 63.6 16.5 75.9 94.4 54.1 14.9 28.6 36.5 30.2 21.5 52.4 17.1 34.3 46.0 28.2 33.5 34.5 16.0 28.7 23.7 12.0 28.8 17.2 15.0 32.9 FGGY FLJ10986 ENSG00000172456 "FGGY carbohydrate kinase domain containing" Q96C11 1 59296638-59810647 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 77.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 191.7;Cholangiocytes: 343.1;Hepatocytes: 142.3" "Cancer enhanced" "Detected in all" "liver cancer: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 42.9;RH-30: 28.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054971, HPA075137" Approved "Nucleoplasm,Nuclear bodies" NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Nuclear bodies" "HPA054971: , HPA075137: " "unprognostic (4.15e-1)" "unprognostic (1.87e-1)" "unprognostic (2.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (2.20e-3)" "unprognostic (1.47e-3)" "unprognostic (1.80e-2)" "unprognostic (4.09e-1)" "unprognostic (2.78e-1)" "unprognostic (2.92e-1)" "unprognostic (1.47e-1)" "unprognostic (4.36e-3)" "unprognostic (7.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.78e-1)" 4.2 14.6 10.5 2.0 12.8 2.3 6.6 21.8 10.2 6.3 4.5 7.1 7.1 4.7 36.5 5.5 9.9 5.4 11.3 7.4 12.1 19.1 77.1 4.7 3.3 12.9 13.4 4.8 12.0 10.5 9.7 3.0 12.9 7.8 6.7 9.6 7.5 10.3 41.8 5.7 8.1 4.2 9.3 2.8 6.1 4.2 16.5 4.1 7.7 17.1 3.6 7.0 5.2 12.7 4.8 1.4 9.2 3.9 4.7 16.6 0.8 4.1 6.8 2.3 3.4 0.0 3.8 5.4 13.0 11.0 4.1 2.0 1.6 11.9 4.9 42.9 1.1 3.8 2.9 8.6 12.3 2.3 2.4 23.2 10.2 5.0 7.9 10.0 4.6 6.0 2.7 3.4 15.3 5.2 3.0 3.2 5.8 13.0 5.3 6.5 28.3 2.1 12.9 8.8 7.2 3.2 5.6 3.3 12.0 8.0 2.8 2.3 4.7 4.0 2.6 4.7 2.8 7.5 2.9 4.6 12.9 9.2 3.8 1.5 1.3 1.4 3.0 1.3 2.7 5.1 1.4 3.8 2.2 3.6 2.7 4.3 2.2 2.9 3.4 1.1 2.8 1.8 10.5 12.8 21.8 10.2 7.4 12.1 12.9 13.4 12.9 9.3 16.5 12.7 3.7 54.5 191.7 83.2 7.9 20.9 23.8 45.2 14.2 10.1 33.1 66.9 29.9 343.1 40.4 12.9 12.5 9.3 3.7 4.2 17.6 62.6 14.0 33.2 7.5 6.9 2.4 12.2 20.4 42.5 4.5 7.6 7.1 20.4 10.1 5.3 5.3 142.3 11.4 8.4 33.7 11.3 22.4 8.8 7.6 11.4 1.8 6.7 35.6 17.8 11.2 12.2 3.1 39.2 36.0 17.7 7.7 3.0 3.4 19.1 14.9 47.9 91.2 16.4 0.0 31.4 8.9 4.6 11.5 13.5 31.5 4.5 5.1 5.9 17.1 35.5 FIBP FGFIBP ENSG00000172500 "FGF1 intracellular binding protein" O43427 11 65883740-65888531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011729 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA011729: AB_1848579" "unprognostic (1.70e-1)" "unprognostic (6.06e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-1)" "unprognostic (1.37e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (2.23e-1)" "unprognostic (2.95e-1)" "unprognostic (3.10e-3)" "unprognostic (2.13e-1)" "unprognostic (1.29e-1)" "unprognostic (5.50e-2)" "unprognostic (2.39e-1)" "unprognostic (3.18e-1)" "unprognostic (1.83e-2)" "unprognostic (4.89e-2)" 34.1 48.4 48.0 26.8 49.0 32.2 33.0 48.0 55.1 31.1 41.8 30.8 30.4 35.9 29.4 35.6 37.2 22.3 56.8 51.0 50.5 48.3 37.1 31.6 35.6 53.3 47.6 28.6 39.0 32.8 31.2 25.1 54.3 30.6 27.3 19.8 27.9 24.6 53.6 45.7 35.3 30.9 46.6 43.3 37.7 64.9 49.9 40.3 35.9 56.1 42.9 29.7 28.3 47.8 61.0 86.9 48.3 118.6 72.8 91.2 35.9 54.8 110.9 74.3 62.0 36.1 83.1 79.7 98.2 124.1 35.9 65.2 48.5 121.0 48.1 93.7 62.2 77.3 84.1 54.7 99.8 100.7 64.4 73.8 68.3 54.1 114.4 60.0 93.7 61.5 27.4 139.4 98.9 198.2 78.9 88.0 47.8 61.5 130.7 104.9 45.6 196.3 88.5 79.6 87.8 80.4 60.3 110.6 110.5 32.5 113.0 58.1 86.3 79.7 66.4 130.9 40.3 73.8 87.6 48.4 101.1 73.6 30.7 123.5 121.2 98.9 71.1 136.9 74.4 100.7 67.2 64.9 164.7 83.1 52.7 57.0 20.4 101.1 150.0 84.1 100.6 109.4 48.0 49.0 48.0 55.1 51.0 50.5 53.3 47.6 54.3 46.6 49.9 47.8 55.8 12.8 28.0 4.9 57.0 47.3 51.7 105.7 38.7 47.7 66.9 85.6 44.7 42.9 55.7 44.1 31.3 79.4 41.1 61.6 93.9 114.2 176.7 45.3 59.8 52.6 93.5 39.1 7.1 149.3 125.7 50.3 37.2 39.6 67.2 68.6 45.3 36.5 115.0 42.1 7.3 49.2 57.0 75.3 75.9 608.0 36.1 67.9 51.6 3.7 129.3 47.1 101.0 3.5 5.6 98.9 68.8 39.5 60.1 56.1 185.8 150.1 54.9 52.8 19.7 39.2 77.2 100.5 84.0 51.5 52.1 71.8 54.6 79.6 58.8 61.5 FIS1 "CGI-135, H_NH0132A01.6, TTC11" ENSG00000214253 "Fission, mitochondrial 1" Q9Y3D6 7 101239458-101252316 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 891.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA017430 Approved Supported Mitochondria NA NA 140000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA017430: AB_1848608" "unprognostic (1.45e-2)" "unprognostic (8.20e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "unprognostic (1.48e-2)" "unprognostic (1.63e-1)" "unprognostic (7.73e-2)" "unprognostic (6.54e-2)" "unprognostic (5.33e-2)" "unprognostic (2.93e-1)" "unprognostic (1.36e-3)" "unprognostic (3.47e-2)" "prognostic favorable (1.08e-7)" "unprognostic (1.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" 205.8 227.6 202.4 60.0 231.0 110.2 195.2 234.0 230.7 149.5 194.5 211.0 83.0 168.1 100.5 155.9 166.0 70.9 382.2 198.4 213.5 250.5 294.9 140.4 73.2 238.9 222.7 152.3 208.7 201.1 209.3 75.4 237.8 160.3 69.5 34.8 142.4 90.0 475.6 174.3 137.3 83.7 223.9 163.0 194.4 145.5 217.6 84.0 178.9 284.2 63.8 163.2 141.1 256.0 110.1 124.3 94.7 133.6 103.6 136.6 63.5 118.1 139.0 103.2 88.3 81.7 173.2 107.4 145.7 159.4 98.1 64.0 65.8 184.5 56.8 87.9 101.0 49.8 154.7 100.6 124.5 93.1 75.0 131.9 172.5 73.4 111.5 117.2 185.6 60.3 109.0 142.9 155.0 445.1 145.1 160.4 100.8 221.2 123.0 70.7 53.4 235.8 155.1 107.5 120.6 141.9 57.0 261.5 83.0 81.3 88.0 101.5 159.6 120.6 76.6 127.9 125.3 122.2 98.6 61.6 111.7 103.0 159.0 153.9 137.7 135.9 122.3 141.7 126.4 152.7 115.5 115.9 149.6 152.8 115.0 120.5 104.5 126.3 131.6 123.2 155.6 207.9 202.4 231.0 234.0 230.7 198.4 213.5 238.9 222.7 237.8 223.9 217.6 256.0 301.0 102.5 119.1 16.0 127.5 104.9 158.6 158.4 114.4 48.2 220.5 309.2 349.4 207.3 114.8 229.9 16.7 259.8 120.7 334.5 561.5 263.5 208.5 145.4 120.7 205.8 219.4 423.7 13.6 293.4 309.2 166.7 110.1 126.4 136.3 132.4 182.0 384.9 297.0 35.3 13.2 317.9 128.1 170.9 133.5 730.3 193.9 136.0 218.7 15.0 214.1 281.5 171.9 6.6 83.1 232.2 460.4 179.0 184.8 221.0 603.6 891.2 130.9 59.6 98.6 161.1 233.3 188.0 201.2 192.7 135.7 324.1 127.5 247.4 277.5 192.5 FMC1 "C7orf55, HSPC268" ENSG00000164898 "Formation of mitochondrial complex V assembly factor 1 homolog" Q96HJ9 7 139339457-139346328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 84.6;Distal tubular cells: 199.6;Proximal tubular cells: 196.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 67.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045663, HPA050553" Approved Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA045663: AB_2679410, HPA050553: AB_2681173" "unprognostic (3.71e-2)" "unprognostic (1.15e-2)" "unprognostic (3.69e-1)" "unprognostic (3.80e-2)" "unprognostic (8.90e-2)" "unprognostic (9.00e-2)" "unprognostic (4.39e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.19e-1)" "prognostic favorable (5.63e-6)" "unprognostic (1.04e-3)" "unprognostic (2.39e-2)" "prognostic favorable (2.05e-5)" "unprognostic (1.50e-1)" "unprognostic (3.40e-2)" "unprognostic (4.67e-1)" "unprognostic (3.02e-2)" 8.5 11.5 19.1 2.8 20.1 6.2 8.2 20.1 23.1 6.6 20.0 9.7 7.0 8.1 11.6 5.5 9.3 5.2 28.5 19.3 19.8 16.2 17.7 5.2 5.5 20.0 19.8 11.2 10.3 11.1 12.0 3.3 19.9 11.2 5.1 3.1 12.8 7.7 30.5 5.0 7.0 3.7 19.5 6.4 11.3 5.7 19.6 7.5 10.7 39.0 3.0 8.6 5.8 21.5 5.6 19.5 11.2 11.7 6.0 5.2 4.9 1.8 4.6 13.2 9.8 6.6 7.1 12.6 11.3 5.9 10.5 4.3 11.0 4.8 3.2 6.3 67.5 6.1 19.9 29.3 12.8 5.3 8.8 13.5 9.3 4.4 3.7 4.8 10.8 8.6 12.4 18.9 7.6 39.2 12.8 35.7 11.1 9.9 28.2 7.7 5.5 17.6 11.1 5.0 22.1 14.5 6.3 5.2 8.1 1.8 2.5 4.3 5.1 4.7 4.4 5.6 5.0 6.7 7.2 14.4 12.1 11.7 7.7 13.3 10.3 10.9 11.2 6.7 9.9 25.3 13.7 11.4 12.0 20.5 15.7 11.2 3.3 16.1 7.6 21.4 16.9 6.6 19.1 20.1 20.1 23.1 19.3 19.8 20.0 19.8 19.9 19.5 19.6 21.5 31.3 44.8 47.6 0.0 10.1 0.0 0.0 0.0 0.0 0.0 57.1 57.4 0.0 0.0 19.8 84.6 0.0 63.0 11.9 0.0 199.6 35.4 0.0 67.8 40.1 14.5 0.0 0.0 0.0 35.3 24.2 20.3 0.0 43.9 12.6 27.6 0.0 0.0 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 12.9 0.0 0.0 0.0 0.0 23.6 0.0 0.0 4.1 0.0 0.0 196.2 37.2 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 47.6 9.4 40.9 0.0 0.0 FOXRED1 H17 ENSG00000110074 "FAD dependent oxidoreductase domain containing 1" Q96CU9 11 126269055-126278131 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039620, HPA046192" Uncertain Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA039620: AB_2676602, HPA046192: AB_2679580" "prognostic unfavorable (7.36e-4)" "unprognostic (4.62e-2)" "unprognostic (2.71e-1)" "unprognostic (3.47e-3)" "unprognostic (1.76e-1)" "unprognostic (1.84e-1)" "unprognostic (9.59e-2)" "unprognostic (1.43e-1)" "unprognostic (8.14e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.01e-6)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" 8.1 13.8 13.6 5.9 14.6 12.1 7.6 15.3 16.6 5.8 17.1 12.0 10.4 6.7 6.4 9.2 7.5 5.6 21.2 15.0 14.7 14.7 37.4 5.3 10.4 15.3 14.3 4.8 7.8 9.7 8.1 7.1 15.3 6.9 12.9 3.7 7.3 6.8 17.8 7.5 8.6 7.9 14.7 11.1 10.9 8.7 15.8 11.5 6.1 29.4 10.6 7.1 6.0 14.8 23.5 26.6 19.5 24.3 14.2 6.8 26.1 11.6 14.9 22.1 22.1 40.0 24.1 38.2 32.3 9.8 28.7 38.5 51.7 31.5 13.8 20.4 14.3 79.7 16.7 48.2 18.8 19.7 16.4 6.3 12.1 14.9 26.5 6.0 24.7 40.2 46.6 20.6 18.7 32.7 23.1 35.3 16.0 61.8 45.2 37.0 34.1 45.2 20.5 11.9 25.0 21.5 23.8 35.7 13.1 12.2 85.9 33.4 9.0 13.1 10.7 23.8 19.4 12.2 19.0 31.9 16.2 66.5 18.7 1.6 10.1 5.9 6.7 13.4 7.0 7.1 5.3 8.9 12.1 6.2 7.4 6.7 2.0 9.9 9.9 16.8 7.6 8.1 13.6 14.6 15.3 16.6 15.0 14.7 15.3 14.3 15.3 14.7 15.8 14.8 6.1 9.6 11.5 19.6 13.5 3.6 6.2 14.9 8.0 24.8 7.3 7.0 21.7 10.0 10.7 3.7 27.1 27.7 12.2 12.6 7.9 13.6 4.2 7.4 8.7 7.6 13.1 14.9 24.7 13.8 24.1 9.8 17.9 7.8 9.5 17.8 10.0 28.2 20.4 13.5 27.1 12.6 8.2 7.1 5.1 7.2 5.6 8.0 8.8 4.7 7.1 18.6 9.2 14.1 16.1 10.7 5.9 11.3 24.4 4.6 8.9 21.0 6.7 32.2 6.6 8.9 9.6 24.5 24.0 11.0 5.7 21.1 8.9 25.0 14.9 4.8 FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Excitatory neurons: 43.5;Oligodendrocytes: 115.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065748 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA065748: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" 2.4 4.9 4.4 0.9 7.9 2.3 2.1 5.4 5.5 0.6 1.8 1.1 1.0 0.4 1.8 1.3 1.9 0.9 2.9 4.5 4.8 4.2 10.0 1.4 2.0 6.1 6.7 1.0 2.2 1.5 0.9 0.6 5.7 1.2 1.1 1.4 2.4 0.6 8.1 1.2 0.8 1.1 6.1 4.6 0.9 1.0 6.0 0.7 5.7 8.4 0.8 0.7 0.9 7.6 0.6 1.9 0.1 0.0 1.9 1.1 1.4 0.7 0.7 1.0 0.4 0.0 3.5 2.0 0.2 0.8 5.7 0.0 0.9 5.3 1.2 2.3 0.5 1.5 0.8 1.7 0.7 5.5 6.5 0.8 0.2 0.4 0.1 0.7 0.0 4.9 2.7 0.1 0.7 6.0 1.9 2.1 1.6 0.5 4.0 0.3 0.2 0.0 0.4 0.0 2.3 0.0 3.4 3.2 3.2 1.3 4.8 7.1 0.6 2.7 0.0 1.8 1.1 4.7 2.9 1.1 5.2 2.7 1.3 0.0 4.1 1.7 0.4 5.5 1.7 3.4 1.7 0.6 5.8 2.1 1.1 1.8 0.0 1.1 5.1 8.7 0.0 1.4 4.4 7.9 5.4 5.5 4.5 4.8 6.1 6.7 5.7 6.1 6.0 7.6 0.8 0.0 0.0 39.8 3.2 2.7 2.9 0.0 13.6 3.3 6.2 5.5 5.7 4.3 1.3 3.7 4.2 1.5 3.3 0.3 1.9 0.2 2.4 8.4 0.8 1.5 0.0 5.9 43.5 0.7 1.4 1.4 4.6 3.3 0.0 5.9 2.2 6.9 7.4 1.7 23.5 1.2 0.0 8.1 4.7 1.0 0.3 8.2 7.2 17.8 2.1 1.7 0.0 24.6 115.4 0.3 0.1 0.4 1.4 2.6 1.0 10.6 0.0 6.5 0.0 2.4 3.4 0.4 2.0 6.9 2.3 0.3 1.5 10.3 1.1 1.2 FTO "ALKBH9, KIAA1752, MGC5149" ENSG00000140718 "FTO alpha-ketoglutarate dependent dioxygenase" Q9C0B1 16 53701692-54158512 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 173.3;Excitatory neurons: 226.1;Inhibitory neurons: 240.7;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 282.5;Respiratory ciliated cells: 182.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017123, HPA041086, HPA068695" Enhanced Supported Vesicles,Cytosol No No 540000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "CAB017123: , HPA041086: AB_2677293, HPA068695: AB_2732117" "unprognostic (9.74e-2)" "unprognostic (2.49e-1)" "unprognostic (9.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (1.41e-1)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.88e-2)" "unprognostic (6.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-1)" "unprognostic (4.30e-3)" "unprognostic (6.11e-3)" 24.4 33.6 31.8 12.5 36.6 8.2 36.3 30.1 37.7 25.8 31.0 22.2 7.7 26.9 21.4 17.2 25.3 21.6 27.1 35.2 39.5 25.0 17.4 36.8 15.0 29.2 31.3 27.2 20.7 40.6 26.2 20.1 31.9 20.0 14.1 38.4 18.9 23.9 33.1 21.4 12.5 29.9 30.5 16.4 15.0 8.3 33.8 17.0 27.5 23.0 14.8 21.9 18.5 43.9 15.1 26.8 35.0 35.9 67.3 50.4 11.5 35.6 32.2 29.3 8.5 16.8 19.3 34.4 38.2 46.3 16.6 21.7 32.4 34.9 42.5 16.0 25.5 15.5 33.6 31.7 46.2 12.5 17.1 55.9 36.5 26.6 32.5 36.6 44.1 25.1 15.2 8.4 48.1 11.8 28.0 19.2 18.1 15.5 17.5 42.2 52.9 32.3 44.6 12.3 43.0 29.7 40.4 23.6 10.8 33.7 31.1 29.3 42.4 36.4 23.9 19.8 22.1 15.9 13.9 35.0 33.9 22.9 28.7 14.9 17.9 9.7 25.6 22.7 32.4 17.6 24.4 25.9 23.8 17.4 22.5 24.4 2.9 26.4 16.5 9.5 26.6 23.1 31.8 36.6 30.1 37.7 35.2 39.5 29.2 31.3 31.9 30.5 33.8 43.9 15.1 80.1 62.0 173.3 10.3 12.4 10.0 8.6 13.6 22.8 69.1 39.5 22.3 15.7 54.4 7.3 12.5 9.3 10.2 4.8 7.9 9.0 39.1 11.0 18.3 17.4 6.6 9.7 226.1 5.7 7.4 23.1 9.7 9.9 25.9 16.8 11.0 13.8 9.2 16.8 240.7 6.6 10.2 9.0 13.2 69.9 14.3 11.8 10.6 134.0 5.5 19.6 10.3 210.6 282.5 5.5 5.0 15.1 18.7 6.0 4.5 15.8 182.7 14.1 13.1 21.6 16.8 3.5 3.4 11.0 9.1 5.1 12.9 17.8 6.3 7.9 FUNDC1 MGC51029 ENSG00000069509 "FUN14 domain containing 1" Q8IVP5 X 44523639-44542859 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038773 Uncertain NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA038773: AB_10670789" "unprognostic (1.04e-1)" "unprognostic (3.91e-2)" "unprognostic (1.91e-1)" "unprognostic (3.11e-2)" "unprognostic (4.93e-1)" "unprognostic (1.72e-2)" "unprognostic (3.40e-3)" "unprognostic (1.88e-3)" "unprognostic (6.40e-2)" "unprognostic (2.85e-3)" "unprognostic (6.63e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-1)" "unprognostic (2.49e-2)" "prognostic favorable (8.35e-4)" "unprognostic (6.67e-3)" "prognostic favorable (2.58e-4)" 11.5 18.4 30.5 9.5 31.3 11.3 20.4 35.9 37.8 14.4 30.3 12.7 12.5 13.4 22.4 13.1 15.3 15.8 37.6 30.5 34.2 25.2 13.0 10.5 17.8 36.0 31.7 19.0 10.2 28.2 14.8 11.5 34.5 16.3 13.5 34.2 49.2 11.5 17.9 16.2 8.0 12.4 32.0 12.8 29.7 14.4 33.3 20.0 16.8 24.9 16.3 15.5 12.0 32.1 39.4 33.1 36.5 22.4 15.8 21.8 20.8 19.4 29.4 38.2 41.7 41.3 32.2 29.0 19.1 26.6 83.5 21.0 60.4 36.7 46.2 32.2 67.6 32.5 41.5 32.3 23.4 35.3 103.3 22.1 35.3 55.1 27.4 36.6 23.8 30.9 34.9 18.0 45.8 41.6 32.9 42.6 43.3 33.6 38.4 20.3 37.1 21.5 39.1 28.0 20.0 31.6 59.3 32.5 37.7 66.0 65.4 0.1 14.0 23.5 34.1 28.0 21.6 14.0 25.2 34.6 31.1 13.8 31.3 7.5 6.3 10.9 7.3 6.3 9.8 10.8 10.1 11.5 11.6 6.6 11.5 9.0 6.8 11.5 4.6 23.8 10.7 5.5 30.5 31.3 35.9 37.8 30.5 34.2 36.0 31.7 34.5 32.0 33.3 32.1 15.2 19.2 10.8 5.2 12.5 14.8 20.1 67.3 18.2 21.9 18.6 21.2 41.6 27.1 34.1 25.8 6.2 35.3 13.0 14.0 115.4 33.6 1.7 27.1 20.9 15.8 10.2 12.0 5.3 36.8 29.4 20.2 16.8 23.1 7.6 36.4 20.3 14.8 37.5 21.9 6.4 13.8 42.7 14.5 7.2 5.7 23.0 13.6 14.2 6.5 13.1 62.9 17.5 6.6 6.8 34.6 26.0 21.8 14.3 17.5 14.5 50.7 26.4 16.1 13.1 12.9 19.8 19.9 45.4 20.7 16.3 26.5 12.7 35.5 17.1 26.0 FXR2 FMR1L2 ENSG00000129245 "FMR1 autosomal homolog 2" P51116 17 7591230-7614897 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 120.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 63.9;Rod photoreceptor cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011205, HPA022997" Supported Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Cytosol "CAB011205: AB_476964, HPA022997: AB_1849208" "unprognostic (9.57e-2)" "unprognostic (1.23e-1)" "unprognostic (5.15e-3)" "unprognostic (2.61e-1)" "unprognostic (1.62e-1)" "unprognostic (7.56e-3)" "unprognostic (1.96e-1)" "unprognostic (3.50e-3)" "unprognostic (2.15e-1)" "unprognostic (2.18e-1)" "prognostic favorable (3.49e-6)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (2.46e-1)" "unprognostic (2.64e-1)" "unprognostic (7.79e-2)" "unprognostic (7.67e-2)" 19.7 27.9 31.5 11.4 34.3 9.8 17.4 36.5 37.9 21.2 26.9 26.7 13.9 21.7 11.6 20.9 20.1 10.9 66.0 33.2 40.0 22.2 20.6 19.2 14.1 41.1 40.9 20.4 16.2 30.7 33.0 15.5 43.4 21.6 11.5 37.7 19.9 18.2 120.9 22.5 17.4 17.1 33.4 16.8 19.9 27.4 37.2 20.8 17.1 84.4 15.1 23.3 19.4 34.9 36.6 48.3 43.8 45.7 36.7 25.0 33.7 54.2 45.1 77.2 53.2 27.2 11.9 33.8 34.8 37.2 34.1 40.1 58.2 24.8 51.4 39.1 62.4 19.6 42.2 15.9 35.7 0.2 39.8 23.5 35.8 58.8 56.4 43.3 27.1 26.9 35.4 11.6 38.8 18.6 26.9 19.3 26.2 18.9 25.8 37.9 26.6 21.3 28.2 13.0 26.1 47.2 37.3 24.3 37.8 41.3 25.3 14.5 24.3 36.0 22.5 24.0 64.8 19.0 18.6 15.5 41.3 15.8 48.0 2.6 0.8 2.5 0.9 1.0 1.3 0.5 1.5 1.9 1.3 0.9 1.2 1.3 2.1 1.0 0.6 0.9 1.8 0.8 31.5 34.3 36.5 37.9 33.2 40.0 41.1 40.9 43.4 33.4 37.2 34.9 10.3 32.1 17.9 10.7 7.7 11.5 15.4 7.9 2.8 46.9 10.4 8.3 41.7 8.6 9.5 16.5 31.3 15.9 15.1 12.0 1.9 11.6 1.8 11.1 9.2 10.5 9.6 15.6 10.3 9.3 11.5 10.8 10.7 11.0 2.5 12.9 15.0 11.7 9.1 63.9 12.0 10.1 10.2 7.3 9.7 2.7 9.6 7.1 0.0 3.7 7.4 23.3 16.5 8.5 12.4 17.6 12.5 15.4 6.3 15.4 15.5 8.9 7.6 55.8 6.6 14.2 17.7 22.9 28.2 8.7 14.3 17.1 7.6 14.6 7.4 10.3 GABARAP "ATG8A, MM46" ENSG00000170296 "GABA type A receptor-associated protein" O95166 17 7240008-7242449 "Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 498.6;Ductal cells: 462.5;Plasma cells: 482.6;Squamous epithelial cells: 457.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065883 Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 59: Non-specific - Transcription" Vesicles "HPA065883: AB_2685574" "unprognostic (2.58e-1)" "unprognostic (4.55e-3)" "unprognostic (1.92e-1)" "unprognostic (9.08e-2)" "unprognostic (1.19e-1)" "unprognostic (4.30e-2)" "unprognostic (1.36e-1)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.58e-1)" "prognostic favorable (9.52e-5)" "unprognostic (1.85e-1)" "unprognostic (1.45e-2)" "unprognostic (2.09e-1)" "unprognostic (2.85e-2)" "unprognostic (1.22e-2)" "unprognostic (1.58e-1)" 609.8 848.2 777.0 344.7 799.2 478.8 610.9 826.8 1091.7 696.5 776.2 600.1 292.4 548.9 574.9 479.4 561.2 302.8 740.4 753.9 807.5 741.1 625.2 569.8 308.5 819.2 790.0 751.1 732.2 662.1 851.7 302.2 829.3 604.6 372.4 280.6 592.3 385.4 1001.1 662.8 496.8 341.4 817.6 651.6 658.9 604.5 803.0 389.2 552.3 916.4 411.0 534.0 547.5 862.7 233.5 342.1 598.0 404.5 887.1 999.5 227.0 377.1 645.5 330.1 491.2 141.9 200.6 233.9 233.2 672.0 430.6 206.9 428.1 329.7 441.7 421.8 474.4 182.8 301.3 377.3 858.3 118.7 369.6 1016.1 445.4 424.5 378.9 925.6 623.7 350.0 143.6 256.8 577.5 159.4 288.4 267.6 242.0 420.9 329.1 393.8 273.3 318.8 682.9 240.9 262.8 695.8 284.1 262.5 409.4 439.3 333.4 228.4 563.7 363.6 211.1 357.7 314.8 280.6 294.2 152.6 586.1 296.2 383.5 2968.2 4092.7 3746.6 766.9 3665.8 796.1 1262.2 906.3 810.4 3152.3 1156.6 812.9 765.5 7095.7 734.6 3213.5 2410.2 1132.5 4745.4 777.0 799.2 826.8 1091.7 753.9 807.5 819.2 790.0 829.3 817.6 803.0 862.7 24.0 89.8 120.1 44.4 183.6 20.8 3.9 21.3 498.6 2.4 64.1 31.9 0.5 54.3 81.3 27.6 0.0 24.3 35.8 302.0 43.0 462.5 24.1 25.5 32.4 61.5 396.5 179.3 36.7 309.6 31.1 124.2 264.6 24.8 150.0 6.9 45.0 39.9 78.2 1.7 37.7 314.3 34.6 147.0 60.8 71.3 21.1 397.4 33.8 43.1 399.2 15.1 32.0 21.1 87.8 375.2 374.3 13.9 482.6 6.0 384.7 72.0 166.4 3.0 6.6 5.2 74.2 22.1 5.8 457.2 23.2 52.9 105.2 5.2 237.1 4.9 GABARAPL2 "ATG8, ATG8C, GATE-16, GATE16, GEF2" ENSG00000034713 "GABA type A receptor associated protein like 2" P60520 16 75566375-75577881 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036726 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA036726: AB_10672476" "unprognostic (3.29e-2)" "unprognostic (3.16e-2)" "unprognostic (1.30e-2)" "unprognostic (7.00e-2)" "unprognostic (4.44e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.58e-1)" "unprognostic (6.85e-2)" "unprognostic (2.13e-1)" "unprognostic (4.95e-2)" "unprognostic (9.86e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.95e-8)" "unprognostic (3.11e-3)" "unprognostic (3.84e-3)" "unprognostic (1.37e-2)" "unprognostic (3.85e-1)" 129.2 166.9 269.1 68.0 278.1 101.6 122.3 297.7 310.8 105.9 237.2 118.5 67.1 101.3 158.1 91.9 106.0 84.1 279.9 259.7 294.9 153.8 113.6 111.3 94.7 280.8 278.4 108.7 81.4 209.5 169.0 113.8 289.2 113.7 81.4 201.4 100.8 102.2 262.9 135.0 90.1 98.6 306.0 112.0 99.7 78.3 282.4 102.1 124.5 186.7 98.9 95.3 104.8 320.2 103.4 85.9 142.7 67.7 217.1 189.9 72.6 118.2 169.9 158.0 176.4 79.8 129.1 148.1 143.0 135.3 95.2 86.6 107.6 110.6 193.9 64.8 208.7 86.9 72.2 119.1 118.2 84.1 151.3 132.0 153.5 133.3 98.6 143.0 130.5 130.5 130.3 58.4 160.2 145.7 125.4 161.0 85.8 114.5 95.8 139.4 69.0 179.6 166.2 66.4 167.7 175.5 184.7 43.7 177.4 113.3 140.1 130.4 119.5 67.9 104.7 100.0 64.5 166.2 172.8 310.6 163.6 80.6 102.6 345.1 148.8 370.8 128.4 140.3 163.0 215.0 135.2 146.8 176.8 199.0 121.4 114.6 502.5 115.3 157.0 274.1 208.1 241.5 269.1 278.1 297.7 310.8 259.7 294.9 280.8 278.4 289.2 306.0 282.4 320.2 341.0 86.6 136.2 30.7 163.9 274.9 278.8 311.4 141.7 247.9 196.5 236.2 361.4 145.8 212.5 174.7 45.9 251.3 188.5 201.5 686.7 183.9 48.2 209.6 112.8 270.1 277.8 457.6 37.0 175.4 120.6 203.5 80.5 162.4 110.1 85.9 239.8 128.5 223.9 307.9 39.6 156.4 297.0 169.6 428.8 59.7 243.5 197.2 257.9 21.5 404.6 491.0 145.2 27.6 63.6 223.6 237.0 261.1 137.5 306.1 195.7 552.4 263.0 208.1 157.8 182.1 187.9 288.1 219.9 136.6 273.9 390.1 159.3 182.5 121.2 328.6 GADD45GIP1 "CKBBP2, CKbetaBP2, CRIF1, MGC4667, MGC4758, PLINP-1, Plinp1, PRG6" ENSG00000179271 "GADD45G interacting protein 1" Q8TAE8 19 12953119-12957223 "Predicted intracellular proteins, Ribosomal proteins" "Cell cycle, Host-virus interaction" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055205, HPA065048, HPA071910" Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA055205: AB_2682736, HPA065048: AB_2685412, HPA071910: " "unprognostic (5.82e-2)" "unprognostic (2.62e-2)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (8.14e-3)" "unprognostic (2.49e-1)" "unprognostic (1.20e-1)" "unprognostic (1.65e-1)" "unprognostic (9.67e-2)" "unprognostic (7.73e-3)" "unprognostic (1.06e-1)" "unprognostic (7.09e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (1.50e-2)" "unprognostic (1.73e-1)" 32.0 46.3 28.9 14.0 28.8 20.6 29.9 28.7 41.3 32.0 27.2 39.0 12.4 34.4 7.7 41.8 30.7 7.5 75.7 28.4 31.0 42.0 52.2 25.2 13.5 31.1 33.1 28.7 39.0 11.6 34.6 11.0 30.6 37.1 4.8 7.4 28.9 9.5 80.1 31.4 25.4 6.8 28.5 32.5 33.1 22.7 30.4 8.8 30.9 23.1 6.5 36.3 28.4 29.9 68.7 56.9 23.5 33.2 16.1 20.8 32.7 49.4 24.5 48.2 39.5 79.1 27.1 49.1 79.8 29.8 34.7 47.0 28.9 48.2 12.4 32.1 140.5 34.9 78.6 90.2 39.2 58.2 51.3 24.7 38.4 33.6 27.5 25.7 28.3 46.1 53.6 18.8 30.3 100.6 93.2 122.8 65.0 44.0 176.7 68.1 23.7 79.2 38.1 39.9 71.9 65.7 36.8 49.3 60.4 11.6 38.4 54.7 46.4 93.0 32.9 81.7 92.3 73.4 55.1 52.0 64.5 72.7 54.8 13.4 35.6 12.6 33.3 34.6 33.1 102.5 51.3 53.1 43.6 84.1 55.1 40.0 2.1 39.9 29.9 41.4 46.9 29.5 28.9 28.8 28.7 41.3 28.4 31.0 31.1 33.1 30.6 28.5 30.4 29.9 111.9 41.7 51.6 6.5 132.4 145.4 189.2 198.9 83.6 59.9 127.0 141.1 157.0 114.4 123.4 138.0 22.9 321.9 101.5 232.1 401.1 265.8 41.8 166.8 139.9 151.8 139.1 159.3 6.1 381.7 355.8 138.3 88.2 130.6 73.6 158.1 146.7 288.8 245.5 37.0 8.1 205.7 101.7 132.9 228.9 56.0 191.3 106.0 179.7 8.4 253.1 103.9 95.8 7.1 14.7 311.5 138.3 170.4 142.4 247.0 215.9 616.7 160.6 88.8 190.7 141.0 164.4 85.4 129.4 153.3 160.8 204.3 105.6 235.8 258.9 171.0 GATB "PET112, PET112L" ENSG00000059691 "Glutamyl-tRNA amidotransferase subunit B" O75879 4 151670504-151761007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Muller glia cells: 333.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042610 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA042610: AB_10797502" "unprognostic (2.52e-1)" "unprognostic (3.33e-1)" "unprognostic (1.01e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (2.06e-1)" "unprognostic (6.76e-2)" "unprognostic (1.37e-1)" "unprognostic (8.17e-2)" "prognostic favorable (1.20e-10)" "unprognostic (1.91e-1)" "unprognostic (8.39e-2)" "unprognostic (3.09e-2)" "unprognostic (2.46e-1)" 11.8 15.6 15.4 5.6 17.5 9.5 8.3 18.0 20.4 6.7 14.9 9.8 5.8 5.5 8.3 10.3 8.7 5.5 33.3 16.3 16.9 21.6 22.2 5.3 7.6 17.4 16.5 11.3 5.3 18.3 5.2 8.6 17.1 5.5 9.6 17.0 7.9 6.4 23.0 9.4 6.4 8.0 17.7 6.5 8.2 8.0 17.2 12.2 7.5 40.3 9.7 6.9 6.1 20.4 14.9 11.6 16.1 15.7 22.9 21.7 13.9 19.3 24.9 33.3 25.8 19.5 23.8 20.2 5.0 20.1 20.3 13.7 34.5 36.6 35.3 11.4 21.1 9.4 15.2 40.7 22.4 19.1 9.0 22.8 23.1 32.0 11.2 19.2 25.1 28.0 36.8 17.1 26.0 16.7 24.1 20.8 16.6 12.4 21.1 20.4 15.5 16.1 30.2 12.3 16.5 18.5 15.8 21.1 23.1 15.4 17.9 13.7 14.1 16.8 9.1 11.7 13.4 20.3 28.2 16.8 23.7 16.9 12.5 0.9 11.6 2.0 4.5 16.9 7.3 11.4 6.1 6.5 20.9 9.9 7.8 7.3 1.1 8.7 12.1 8.1 7.0 10.8 15.4 17.5 18.0 20.4 16.3 16.9 17.4 16.5 17.1 17.7 17.2 20.4 4.3 9.6 4.8 11.4 6.7 0.0 6.0 0.0 5.7 9.8 6.3 7.1 64.8 1.5 3.7 11.0 8.4 23.4 2.9 3.2 27.4 11.2 8.0 6.7 7.3 4.4 2.4 15.6 28.4 7.4 16.6 8.8 6.6 7.1 1.3 12.3 2.5 17.2 17.1 10.1 16.4 4.2 0.0 7.3 0.0 10.6 5.3 7.6 0.0 15.9 10.8 333.3 1.0 14.1 27.5 6.9 4.9 4.5 5.6 3.1 6.3 22.7 1.5 17.1 6.6 6.5 5.9 14.3 14.0 10.6 0.0 13.4 3.6 12.5 7.1 4.5 GATD3B ENSG00000280071 "Glutamine amidotransferase like class 1 domain containing 3B" A0A0B4J2D5 21 5079294-5128413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal tubular cells: 17.6;Ductal cells: 6.9;Hofbauer cells: 8.0;monocytes: 7.8;Proximal tubular cells: 31.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA018517 Uncertain Approved Centrosome,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Centrosome "HPA018517: AB_2669899" "unprognostic (4.87e-2)" "unprognostic (2.69e-3)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (2.96e-1)" "unprognostic (6.47e-2)" "unprognostic (1.43e-2)" "unprognostic (2.39e-2)" "unprognostic (7.65e-2)" "unprognostic (1.71e-2)" "unprognostic (1.15e-2)" "unprognostic (3.33e-2)" "unprognostic (6.67e-4)" "unprognostic (1.88e-2)" "unprognostic (6.80e-2)" "unprognostic (4.25e-1)" "unprognostic (2.84e-2)" 53.8 77.8 82.0 34.9 87.3 31.7 48.6 88.9 90.2 40.9 76.0 55.1 71.8 36.9 27.5 59.4 44.4 41.2 195.5 78.2 87.4 141.7 239.9 34.5 53.8 89.0 86.3 66.6 52.7 61.9 54.8 40.2 90.2 43.9 57.5 32.2 60.1 33.4 208.0 40.6 51.3 32.4 83.9 48.2 50.1 33.0 89.9 35.9 55.1 225.6 28.1 40.0 41.1 85.5 55.8 52.7 57.1 98.7 42.8 38.3 23.7 0.0 4.5 1.9 2.9 7.0 54.8 2.6 61.9 62.9 51.7 38.8 77.2 34.7 1.1 36.8 32.8 217.2 60.1 47.6 41.7 94.8 39.7 80.4 69.6 28.3 57.1 39.5 64.4 66.1 86.6 51.2 34.9 118.5 94.4 103.6 110.9 150.0 80.5 190.1 43.1 223.3 72.4 49.8 48.5 96.4 76.7 138.9 52.0 28.4 146.2 131.4 19.7 27.7 39.0 2.5 33.7 80.7 79.2 37.6 64.9 192.0 20.7 87.3 110.4 60.4 102.2 123.5 101.4 153.3 129.7 107.0 147.7 167.1 124.6 95.2 21.7 136.1 167.7 96.3 145.3 190.3 82.0 87.3 88.9 90.2 78.2 87.4 89.0 86.3 90.2 83.9 89.9 85.5 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.0 0.0 2.9 1.4 0.0 17.6 6.9 0.0 1.1 1.9 0.7 0.0 0.0 0.0 5.0 3.2 0.3 0.0 2.0 0.0 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 7.8 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.7 0.0 0.0 31.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.4 0.7 1.9 0.0 0.0 GBF1 "ARF1GEF, KIAA0248" ENSG00000107862 "Golgi brefeldin A resistant guanine nucleotide exchange factor 1" Q92538 10 102245371-102382899 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 28.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037759, HPA037760" Uncertain Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA037759: AB_10671884, HPA037760: AB_2675651" "unprognostic (5.97e-2)" "unprognostic (3.33e-1)" "unprognostic (2.74e-3)" "unprognostic (7.02e-2)" "unprognostic (2.03e-1)" "unprognostic (6.72e-2)" "unprognostic (3.78e-2)" "unprognostic (8.28e-2)" "unprognostic (1.12e-2)" "unprognostic (5.34e-3)" "unprognostic (2.04e-2)" "unprognostic (6.06e-2)" "unprognostic (1.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (3.02e-1)" "unprognostic (3.09e-2)" 19.4 21.1 31.5 16.0 31.7 25.0 19.3 28.7 47.2 21.7 34.9 24.6 20.6 23.5 12.7 21.9 19.7 9.8 30.0 32.2 27.7 21.7 23.2 20.5 14.6 28.5 37.3 21.6 25.6 24.4 31.5 11.5 30.6 24.2 13.9 19.2 24.5 15.2 48.1 24.9 25.8 16.4 27.1 21.7 21.2 20.5 29.8 11.8 25.4 30.1 13.8 21.7 20.5 29.1 19.4 49.7 23.3 25.1 62.9 40.7 28.1 37.7 56.0 45.3 48.1 52.7 35.1 21.7 29.7 59.6 33.8 38.6 45.9 52.8 33.8 35.4 36.9 33.3 38.1 44.6 26.4 35.2 46.8 37.3 28.0 60.7 57.5 77.2 45.2 22.5 20.7 53.7 41.8 36.9 24.2 38.9 15.4 29.5 35.6 33.6 72.1 18.8 39.3 30.9 15.0 16.3 30.2 22.3 26.5 33.1 50.4 30.8 60.5 29.1 29.6 37.7 55.6 32.4 36.3 26.5 30.0 36.3 22.1 28.6 4.5 4.3 4.9 5.0 5.9 6.5 3.6 6.5 5.0 3.9 5.7 5.3 4.6 4.6 4.1 4.2 7.4 3.9 31.5 31.7 28.7 47.2 32.2 27.7 28.5 37.3 30.6 27.1 29.8 29.1 12.5 12.8 10.1 56.5 15.5 9.8 5.5 10.6 17.6 24.7 15.7 12.8 17.0 15.7 10.9 12.9 56.3 12.2 15.1 31.4 3.9 12.5 4.9 14.3 18.1 12.3 12.0 13.9 72.1 16.7 16.3 14.6 31.1 15.6 7.6 10.3 8.2 17.6 12.2 52.2 73.0 21.9 12.2 11.0 5.0 4.7 10.2 13.4 12.4 66.5 9.5 11.1 9.2 80.9 71.1 18.6 20.7 11.3 46.0 7.7 27.1 9.0 12.3 41.0 6.6 21.7 12.3 36.0 25.4 20.7 13.1 17.6 16.0 19.1 19.4 6.7 GCFC2 "C2orf3, DNABF, GCF, TCF9" ENSG00000005436 "GC-rich sequence DNA-binding factor 2" P16383 2 75652000-75710985 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077882 Approved Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA077882: AB_2686864" "unprognostic (1.98e-1)" "unprognostic (5.18e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (9.59e-4)" "unprognostic (5.67e-3)" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (3.74e-2)" "unprognostic (8.80e-2)" "unprognostic (4.21e-2)" "unprognostic (1.63e-1)" "unprognostic (5.71e-2)" "unprognostic (3.20e-2)" "unprognostic (8.37e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.07e-2)" 10.7 10.5 13.8 4.2 16.3 7.4 12.1 14.4 17.3 19.2 9.7 9.7 3.7 11.1 11.4 9.6 13.7 4.7 11.3 12.2 14.4 19.0 28.5 7.8 8.8 13.7 14.5 14.3 14.1 7.5 11.2 6.9 13.9 14.0 3.8 11.7 7.8 5.5 29.1 15.8 8.1 6.3 15.1 12.3 9.4 12.0 14.4 7.6 12.1 9.1 6.5 9.0 10.4 17.3 14.4 13.9 9.8 11.6 5.3 6.7 12.7 9.5 7.7 9.7 9.2 16.7 10.3 14.2 13.4 6.5 11.9 5.5 11.9 6.5 13.0 20.9 25.5 10.9 13.6 44.9 8.3 18.8 10.2 7.2 8.2 4.8 14.5 11.0 11.6 17.6 16.5 8.2 9.3 11.3 19.6 31.8 15.5 10.5 15.3 22.8 20.1 34.6 16.3 15.7 18.0 22.6 12.8 14.5 16.2 6.9 10.8 10.6 12.6 9.3 12.2 13.4 19.3 9.5 17.7 10.8 9.2 11.7 20.7 0.6 8.1 3.8 10.4 5.7 11.9 18.2 9.7 12.1 9.4 12.6 14.3 13.2 0.4 5.4 9.6 13.3 11.5 8.9 13.8 16.3 14.4 17.3 12.2 14.4 13.7 14.5 13.9 15.1 14.4 17.3 11.6 16.0 11.2 49.6 15.7 27.8 20.5 14.0 21.6 11.2 14.4 13.5 22.4 17.2 20.2 12.9 0.0 36.7 14.8 7.3 21.5 16.0 31.5 11.4 18.0 15.0 16.2 12.0 60.8 19.0 23.5 21.9 8.2 8.7 13.9 15.6 13.2 24.9 12.5 16.8 51.7 7.5 8.2 13.9 12.0 75.4 16.8 8.8 14.2 20.6 7.1 10.6 16.5 75.9 75.9 13.8 7.8 9.8 11.3 18.0 6.2 19.3 15.1 9.1 13.1 20.2 13.5 15.5 22.7 16.5 24.7 23.7 13.3 17.4 10.6 16.8 GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 553.4;Extravillous trophoblasts: 1476.4;Proximal tubular cells: 655.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" 28.7 20.1 58.9 6.9 66.5 6.3 24.2 62.9 113.8 18.2 50.8 16.0 7.2 17.5 68.9 15.5 19.8 11.7 38.1 55.8 60.9 78.2 118.9 10.8 6.7 60.1 66.0 18.4 19.7 31.0 14.3 26.0 61.1 18.7 13.0 15.6 15.6 16.7 59.3 10.1 9.5 11.8 61.7 6.3 17.5 7.4 63.7 10.4 96.4 63.6 9.3 18.3 15.2 67.8 63.6 28.3 82.4 37.0 40.4 30.9 175.5 35.9 26.4 43.3 20.6 37.0 57.2 17.2 32.3 15.9 31.9 33.3 64.5 36.5 71.6 4.7 86.7 21.8 34.9 114.6 45.7 70.3 24.1 32.0 47.8 26.8 53.7 13.0 22.3 45.1 86.3 3.4 42.9 67.7 45.9 138.8 113.0 49.6 57.5 72.7 44.1 25.5 98.4 56.4 43.7 45.3 53.3 32.9 70.8 63.9 48.3 33.2 19.8 27.6 49.3 44.0 37.8 14.7 31.8 102.1 18.2 41.3 22.6 3.6 1.3 1.3 2.8 2.1 4.6 3.5 2.6 4.0 3.9 2.5 4.4 5.9 1.7 7.0 1.7 10.8 2.2 2.4 58.9 66.5 62.9 113.8 55.8 60.9 60.1 66.0 61.1 61.7 63.7 67.8 31.1 3.2 5.9 16.3 24.8 29.1 94.6 73.6 52.3 43.7 97.9 115.6 12.9 44.3 31.4 80.9 37.5 553.4 13.8 15.3 295.4 70.0 32.4 34.8 128.3 31.9 26.4 71.1 12.6 42.5 1476.4 61.6 31.1 55.2 36.3 38.5 33.2 352.0 118.8 38.7 11.9 34.3 67.1 19.7 34.6 19.5 140.8 18.8 85.4 4.7 17.7 215.8 19.6 19.6 35.2 42.3 17.8 141.1 51.7 123.9 13.7 655.9 20.0 45.7 32.9 46.2 50.2 20.7 77.3 78.4 27.1 228.8 16.3 114.5 49.4 69.8 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501693-19522123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Nucleoplasm, Plasma membrane" "HPA077420: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favorable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 28.9 25.9 42.9 15.6 46.3 27.8 21.1 42.9 49.9 21.9 40.4 44.9 30.0 20.0 27.5 22.4 16.9 18.4 52.8 45.7 45.5 27.6 25.4 29.3 11.7 44.5 47.7 12.8 28.5 76.8 19.2 20.5 43.3 26.7 41.6 19.8 28.3 30.3 62.9 26.4 27.7 26.5 42.8 13.5 34.3 14.1 48.8 16.8 20.3 64.4 15.3 30.2 16.6 47.4 38.6 46.2 25.0 29.4 115.3 43.3 34.7 38.3 66.9 30.0 37.1 26.6 67.4 29.2 48.1 57.2 32.8 31.8 35.2 46.6 36.9 31.7 52.8 24.2 41.4 57.2 69.1 32.7 21.5 44.9 73.1 32.2 37.4 54.5 40.6 36.3 13.7 29.1 33.2 70.3 28.3 29.1 29.1 59.9 34.2 40.2 45.7 41.7 72.9 59.7 28.9 25.8 37.0 44.5 37.9 38.5 45.8 37.8 42.7 25.3 22.3 33.9 24.6 27.0 27.4 19.9 38.5 47.2 23.1 52.0 19.3 11.2 8.9 17.7 11.5 7.2 10.4 10.4 12.4 6.1 5.5 8.5 34.0 6.6 22.7 7.5 12.7 8.2 42.9 46.3 42.9 49.9 45.7 45.5 44.5 47.7 43.3 42.8 48.8 47.4 12.2 38.5 86.8 7.2 18.9 23.5 30.3 56.2 22.8 15.4 38.3 22.4 66.8 34.3 56.0 9.2 27.1 80.4 23.2 123.1 23.5 97.0 35.1 26.9 23.8 17.7 33.5 100.8 12.0 163.9 78.6 27.3 24.5 21.5 3.8 36.4 20.7 23.9 60.8 32.0 15.9 57.5 61.1 48.2 22.9 61.2 28.6 32.3 24.9 8.4 38.2 22.3 24.7 9.5 25.0 77.4 97.6 38.0 19.6 100.5 101.7 45.9 39.7 29.6 13.1 16.7 24.9 87.1 59.6 31.9 29.5 270.4 22.0 45.9 85.3 79.2 GDPGP1 C15orf58 ENSG00000183208 "GDP-D-glucose phosphorylase 1" Q6ZNW5 15 90233808-90245811 "Enzymes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA048189, HPA059841" Approved Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA048189: AB_2680307, HPA059841: AB_2684138" "prognostic favorable (6.32e-4)" "unprognostic (1.85e-1)" "unprognostic (2.17e-1)" "unprognostic (2.42e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (2.58e-1)" "unprognostic (3.68e-2)" "unprognostic (4.46e-3)" "unprognostic (1.53e-1)" "unprognostic (3.00e-1)" "unprognostic (1.82e-2)" "unprognostic (2.93e-3)" "unprognostic (8.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.02e-3)" 1.8 3.2 3.9 3.0 3.0 2.0 2.3 4.3 4.2 2.0 3.1 5.7 5.3 2.2 3.0 2.4 4.6 3.0 5.8 3.2 2.9 4.3 4.9 2.9 3.5 3.7 2.9 2.9 3.5 4.9 3.7 1.0 4.6 3.7 7.7 2.7 3.8 3.1 7.9 2.1 3.9 2.8 1.8 3.2 3.5 4.6 2.9 3.1 3.8 1.5 4.1 3.4 1.5 5.0 3.0 11.8 1.4 4.3 4.3 0.9 3.9 2.7 1.7 3.5 3.3 3.5 11.5 7.5 5.2 2.1 2.6 5.0 4.5 3.2 1.4 6.7 7.8 6.7 7.0 5.1 4.6 3.6 4.2 1.1 2.1 2.4 1.3 3.9 4.2 4.4 2.5 2.6 2.1 6.5 2.7 1.6 1.8 9.2 4.8 4.7 1.0 3.8 4.1 5.9 4.5 2.0 4.3 6.6 4.5 2.6 7.6 3.7 4.2 1.8 1.9 2.7 2.7 5.8 7.3 3.4 4.1 3.0 3.3 3.8 2.2 1.0 3.1 2.6 2.7 2.3 2.9 3.7 2.0 4.2 3.0 2.8 3.1 3.4 2.2 2.1 3.9 1.4 3.9 3.0 4.3 4.2 3.2 2.9 3.7 2.9 4.6 1.8 2.9 5.0 1.4 0.0 3.2 0.3 2.1 0.0 2.8 0.9 1.8 3.8 3.4 2.2 6.4 8.6 1.5 7.3 6.2 2.4 2.5 6.5 3.9 3.8 3.0 3.8 1.6 1.7 5.4 1.7 2.6 6.0 1.2 1.5 4.1 2.3 3.8 2.3 1.4 4.5 4.1 1.7 2.8 3.6 0.0 2.2 0.0 2.4 2.8 3.5 0.0 1.0 2.3 3.5 2.1 1.0 2.1 4.9 5.5 2.2 2.4 2.2 3.8 5.8 3.4 4.4 0.0 3.8 1.0 2.9 2.8 1.8 0.3 0.4 3.2 1.5 4.2 3.1 GET3 "ARSA-I, ASNA1, TRC40" ENSG00000198356 "Guided entry of tail-anchored proteins factor 3, ATPase" O43681 19 12737139-12748323 "Predicted intracellular proteins, Transporters" Transport Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 106.6;Extravillous trophoblasts: 80.7;Hofbauer cells: 142.4;Syncytiotrophoblasts: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045951, HPA048087" Approved Enhanced Nucleoplasm,Nucleoli NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoli Nucleoplasm "HPA045951: AB_2679511, HPA048087: AB_2680258" "unprognostic (2.87e-1)" "prognostic favorable (9.53e-4)" "unprognostic (1.01e-1)" "unprognostic (2.16e-1)" "unprognostic (2.05e-2)" "unprognostic (5.70e-2)" "unprognostic (2.01e-2)" "unprognostic (1.33e-2)" "unprognostic (3.34e-1)" "unprognostic (3.08e-2)" "unprognostic (1.85e-1)" "unprognostic (4.39e-2)" "prognostic favorable (4.27e-5)" "unprognostic (6.11e-2)" "unprognostic (5.77e-2)" "unprognostic (2.32e-3)" "prognostic unfavorable (8.47e-4)" 47.5 61.6 56.4 39.4 58.2 66.2 46.5 59.0 72.8 48.4 62.4 43.0 39.9 49.8 41.0 58.1 47.0 39.3 62.0 59.6 58.4 61.6 38.4 40.8 48.3 55.4 57.3 41.9 48.2 73.3 48.2 28.0 57.9 34.3 28.7 36.4 47.3 31.4 67.6 59.1 38.7 33.9 55.9 43.4 50.9 60.2 58.9 46.9 56.3 58.6 38.1 46.3 43.3 57.3 143.7 116.5 60.7 132.3 118.6 72.4 74.6 72.4 99.7 137.5 107.6 90.3 69.6 64.8 111.0 95.4 157.5 75.2 84.5 97.6 65.4 100.9 132.7 54.3 82.4 105.3 125.8 83.5 104.9 83.6 84.1 111.3 66.1 89.2 99.4 75.9 71.3 86.8 109.5 320.4 112.9 68.1 154.6 92.0 215.6 82.2 93.6 128.4 130.2 120.7 111.6 95.5 97.3 131.3 119.8 51.5 108.2 80.5 85.5 193.3 65.4 217.1 172.4 153.9 279.4 61.7 136.2 137.0 109.0 33.6 44.3 26.3 24.8 34.3 21.2 20.3 22.0 22.2 44.8 17.0 15.7 19.5 15.6 16.7 42.9 29.4 34.2 35.8 56.4 58.2 59.0 72.8 59.6 58.4 55.4 57.3 57.9 55.9 58.9 57.3 14.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 106.6 13.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 80.7 12.5 0.0 0.0 0.0 0.0 0.0 0.0 142.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 110.7 1.7 0.0 0.0 0.0 GHITM "DERP2, HSPC282, My021, PTD010, TMBIM5" ENSG00000165678 "Growth hormone inducible transmembrane protein" Q9H3K2 10 84139509-84153568 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1114.2;Late spermatids: 2559.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016464, HPA061664" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA016464: AB_1849656, HPA061664: AB_2684579" "unprognostic (6.26e-3)" "unprognostic (1.85e-1)" "unprognostic (2.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (5.71e-2)" "unprognostic (4.56e-2)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (8.14e-2)" "unprognostic (5.71e-2)" "prognostic favorable (2.32e-10)" "unprognostic (2.46e-2)" "unprognostic (2.09e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" 113.9 179.5 124.3 87.0 133.3 110.6 93.8 138.6 147.7 73.1 150.6 171.2 163.5 76.8 86.1 114.4 71.4 68.9 365.3 136.1 146.1 300.7 271.1 74.1 87.3 136.6 128.1 72.7 77.7 197.3 88.8 70.3 138.5 80.6 166.4 144.3 94.4 84.2 369.3 79.7 137.1 85.7 125.4 73.8 123.1 115.7 137.5 86.5 105.9 456.6 103.3 92.3 76.5 123.1 228.2 230.8 97.1 223.5 162.6 143.3 171.6 153.3 267.4 193.7 180.2 283.1 183.8 178.9 167.7 203.2 170.9 199.9 208.4 200.0 185.9 179.8 157.4 127.7 227.3 281.0 306.5 402.0 200.0 162.7 384.1 200.4 577.8 201.8 169.9 150.5 299.9 324.3 180.4 197.4 143.6 318.9 98.3 184.8 203.2 128.3 89.4 270.5 271.4 179.2 79.4 92.4 154.7 134.1 325.1 111.2 273.7 254.2 145.3 94.0 126.5 138.5 251.1 227.9 265.7 199.9 246.8 364.4 67.1 293.7 284.9 276.5 173.9 304.7 194.2 211.0 178.9 186.0 279.9 177.9 166.6 178.8 223.7 206.7 281.3 145.3 235.3 578.0 124.3 133.3 138.6 147.7 136.1 146.1 136.6 128.1 138.5 125.4 137.5 123.1 94.1 96.1 87.6 23.2 138.0 170.3 185.1 440.9 87.0 135.9 102.2 71.8 689.3 140.2 235.8 158.2 70.9 260.4 134.0 376.0 579.2 295.3 1114.2 58.7 68.6 120.7 125.6 242.9 33.6 232.3 234.9 119.6 107.6 67.1 102.0 79.3 88.5 326.1 267.7 101.0 34.5 206.0 443.5 156.2 169.2 2559.1 110.3 153.0 163.7 16.9 228.3 269.0 114.4 14.6 24.3 223.3 276.3 136.9 167.3 180.1 343.7 802.9 173.4 159.9 144.7 114.5 219.8 263.1 153.2 150.4 170.3 386.0 141.6 158.4 281.4 212.9 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703145 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 2571.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 1500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: AB_2684126" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 55.4 62.3 69.4 38.9 74.1 31.6 74.2 74.6 83.4 55.9 77.2 51.8 116.3 57.8 110.9 60.0 72.3 41.4 88.9 72.6 76.2 87.2 157.7 66.6 48.4 73.7 72.8 82.8 42.1 106.1 23.2 64.1 75.1 171.4 52.3 100.3 43.2 62.1 154.2 66.6 67.7 61.8 77.9 48.2 48.5 27.9 72.9 50.0 54.8 128.8 60.3 52.4 51.6 77.1 201.6 92.0 257.4 256.7 119.2 213.9 227.0 171.1 161.4 235.4 243.0 224.4 75.3 222.5 132.2 137.5 280.1 129.5 222.5 221.1 295.8 203.8 343.0 329.4 105.7 211.3 178.5 126.7 2571.5 183.9 133.5 223.7 159.0 153.2 258.5 154.9 264.7 143.6 223.3 170.6 199.5 160.5 185.5 179.2 176.7 171.0 311.1 145.8 217.8 149.9 199.3 201.3 120.6 165.4 329.8 175.9 192.4 628.3 107.6 182.0 167.1 159.8 275.9 112.7 227.0 608.6 66.1 322.7 299.6 23.7 20.7 15.3 35.5 33.4 48.0 51.9 35.3 36.7 39.0 51.4 32.7 34.9 2.7 23.5 26.9 60.4 34.1 33.3 69.4 74.1 74.6 83.4 72.6 76.2 73.7 72.8 75.1 77.9 72.9 77.1 69.2 131.4 174.4 26.1 86.3 64.6 112.6 88.2 37.0 56.1 67.7 55.8 133.2 58.6 84.5 90.1 20.9 102.7 68.3 34.1 248.4 132.1 4.5 76.2 58.8 74.3 36.5 83.5 23.9 73.3 323.0 86.0 53.0 67.5 71.4 78.7 161.0 114.0 78.8 69.0 21.9 39.3 99.7 125.7 72.8 6.5 83.9 70.0 104.9 17.8 92.6 190.3 49.4 25.1 24.8 77.3 36.0 109.9 86.4 178.8 103.2 132.2 80.7 65.5 46.0 62.0 70.9 15.0 16.1 77.2 88.2 73.2 62.4 123.7 63.4 130.2 GLRX2 "bA101E13.1, GRX2" ENSG00000023572 "Glutaredoxin 2" Q9NS18 1 193090866-193106114 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 17 "Early spermatids: 796.4;Late spermatids: 1841.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 240.2" "Low region specificity" "Detected in all" "HPA023087, HPA057224" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA023087: AB_1849778, HPA057224: AB_2683373" "unprognostic (4.80e-2)" "unprognostic (3.77e-2)" "unprognostic (8.04e-2)" "unprognostic (2.33e-1)" "unprognostic (1.13e-1)" "unprognostic (4.99e-2)" "unprognostic (2.40e-3)" "unprognostic (5.11e-2)" "unprognostic (3.21e-2)" "unprognostic (2.38e-2)" "unprognostic (1.10e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (3.30e-7)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (6.21e-2)" "unprognostic (4.48e-2)" 16.1 22.3 16.0 7.9 16.5 9.5 12.4 17.0 28.7 10.2 15.4 14.4 11.7 8.2 10.7 16.7 7.2 6.9 37.0 16.5 18.2 16.2 25.9 9.8 5.2 17.3 15.8 6.2 9.6 5.5 8.4 7.5 17.9 17.9 9.0 2.5 11.1 8.4 37.6 12.9 10.6 8.7 15.9 9.8 12.9 30.2 16.8 3.8 7.2 24.8 7.3 13.9 11.7 17.2 47.2 57.8 14.6 32.8 52.2 33.9 24.0 67.2 29.8 55.6 45.9 36.3 44.2 20.0 36.1 28.6 67.1 44.4 17.5 39.4 56.7 45.6 30.4 40.4 39.0 42.6 55.9 32.8 39.0 23.1 33.8 76.5 38.4 21.6 35.7 13.7 60.8 21.9 68.4 66.3 26.9 60.6 16.8 75.6 38.2 23.7 22.9 48.3 53.7 31.4 13.8 12.4 26.9 81.2 240.2 21.6 35.2 37.5 21.6 42.8 11.2 93.7 70.5 42.6 48.7 41.4 40.8 38.1 61.2 13.6 18.8 26.6 12.7 23.1 14.2 13.2 13.4 11.7 22.5 10.8 11.7 13.4 9.6 16.1 30.0 9.2 18.6 14.5 16.0 16.5 17.0 28.7 16.5 18.2 17.3 15.8 17.9 15.9 16.8 17.2 24.2 9.6 10.1 5.5 14.8 18.2 21.1 39.1 14.2 7.2 21.7 23.6 62.8 12.8 21.5 16.5 6.2 39.2 19.5 25.8 29.4 41.1 796.4 16.1 24.2 18.7 13.8 15.6 11.3 41.4 41.6 25.2 14.8 17.7 46.9 16.4 11.0 30.3 44.2 1.7 10.1 26.5 32.6 15.0 26.9 1841.1 17.4 26.8 26.6 5.6 25.9 9.9 28.8 5.0 10.1 38.3 31.5 18.0 20.5 39.2 40.3 74.3 13.9 11.5 6.6 15.5 36.2 12.3 25.4 21.3 19.9 24.8 14.0 33.1 24.1 20.5 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 511.1;liver: 369.5;skeletal muscle: 489.9;tongue: 1011.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 449.0;Distal tubular cells: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol NA Yes 100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favorable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favorable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 14.7 54.9 67.8 14.7 71.1 8.0 22.7 70.3 119.1 53.1 82.6 50.9 62.0 13.1 25.9 42.7 17.9 49.0 511.1 70.0 77.6 143.1 369.5 15.5 14.1 83.5 55.0 18.1 34.0 142.4 22.5 14.4 83.7 22.7 59.2 106.2 48.6 27.4 489.9 23.9 45.8 21.4 48.4 16.9 58.9 33.6 69.1 17.7 47.7 1011.6 30.3 22.3 21.0 70.1 73.7 40.3 46.0 114.4 35.1 30.7 127.1 58.9 108.7 101.8 109.8 89.9 56.4 71.9 20.4 50.2 89.2 88.6 107.1 78.9 105.8 25.7 46.7 28.1 46.7 114.3 184.9 77.9 44.0 47.3 82.5 86.9 228.4 69.5 49.5 48.6 71.1 106.2 65.4 64.9 42.5 56.5 29.2 118.7 56.1 45.5 44.4 72.8 173.7 37.5 19.6 28.7 44.8 59.3 222.6 66.8 115.7 27.1 23.3 25.4 56.3 28.0 68.7 76.8 99.7 74.3 65.4 40.8 34.1 4.0 8.7 6.8 19.7 25.8 18.4 17.6 21.5 20.7 21.9 21.2 15.6 22.7 0.8 20.5 31.5 36.4 27.6 15.6 67.8 71.1 70.3 119.1 70.0 77.6 83.5 55.0 83.7 48.4 69.1 70.1 10.3 16.0 16.2 26.1 38.8 11.9 41.8 82.7 24.5 95.6 18.8 21.2 449.0 72.9 34.4 73.5 62.6 35.9 10.7 62.1 240.7 51.9 166.7 17.8 9.3 16.7 19.7 39.5 47.4 30.8 18.1 23.5 76.9 21.5 31.8 20.2 17.2 191.8 31.6 75.7 63.3 45.3 54.9 12.4 6.9 24.1 11.1 13.0 49.8 13.1 10.5 36.6 6.2 21.1 37.2 27.6 34.4 14.3 22.4 13.1 97.0 163.3 27.9 76.5 13.1 15.2 20.5 116.7 10.4 40.9 10.4 55.1 14.6 47.0 66.4 42.3 GPS1 "COPS1, CSN1" ENSG00000169727 "G protein pathway suppressor 1" Q13098 17 82050691-82057470 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047448, HPA052848" Enhanced Nucleoplasm,Cytosol NA NA 78000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA047448: , HPA052848: " "unprognostic (1.96e-1)" "unprognostic (5.89e-2)" "unprognostic (1.50e-1)" "unprognostic (9.65e-2)" "unprognostic (3.41e-1)" "unprognostic (2.19e-1)" "unprognostic (4.75e-3)" "unprognostic (2.18e-2)" "unprognostic (3.17e-1)" "prognostic favorable (3.06e-4)" "unprognostic (1.18e-3)" "unprognostic (1.92e-1)" "unprognostic (4.96e-3)" "unprognostic (4.07e-1)" "unprognostic (8.90e-2)" "unprognostic (1.45e-1)" "unprognostic (2.15e-1)" 55.6 64.4 55.9 32.0 56.7 42.7 54.6 59.2 80.5 53.3 53.7 58.8 35.0 56.3 30.9 50.9 49.5 28.1 91.1 59.2 57.6 81.9 101.7 48.6 37.5 60.1 59.2 56.4 69.8 48.4 62.6 29.7 60.0 64.5 18.1 20.5 58.8 40.7 148.5 56.6 46.8 25.5 55.1 54.9 65.5 70.6 56.5 37.3 58.7 63.7 24.9 53.7 48.0 59.2 112.5 204.9 74.7 98.0 51.7 49.5 105.4 73.6 58.2 114.1 93.9 180.7 68.1 55.0 64.5 74.1 83.1 83.1 71.6 94.2 38.7 37.0 256.7 93.5 112.2 203.5 85.5 102.9 86.8 71.2 67.9 101.3 60.0 45.9 120.4 93.4 89.1 62.0 64.3 220.8 176.8 116.4 95.3 107.2 151.3 107.0 102.5 89.5 71.1 114.8 127.6 199.8 74.9 136.6 110.0 56.7 155.1 91.7 69.3 113.3 133.3 88.6 120.5 112.6 51.4 58.9 88.7 65.5 104.5 57.6 85.7 65.9 77.5 81.0 81.8 64.5 80.9 78.3 93.4 64.2 56.9 71.8 13.2 81.6 78.1 64.2 115.2 98.7 55.9 56.7 59.2 80.5 59.2 57.6 60.1 59.2 60.0 55.1 56.5 59.2 24.0 12.8 24.8 27.1 24.9 25.1 22.5 37.1 17.6 30.6 31.0 27.6 53.7 30.0 30.7 20.2 25.0 71.1 22.7 78.6 60.7 50.7 33.0 22.7 22.4 30.0 41.3 21.7 12.1 69.4 67.6 31.0 35.7 23.3 24.7 45.2 28.5 50.6 60.9 48.8 14.2 42.7 52.9 37.3 31.5 76.7 30.1 32.0 33.8 7.5 42.4 46.3 29.9 10.6 16.4 48.1 56.1 31.6 50.1 25.4 58.4 100.9 33.9 27.2 6.6 28.3 36.3 50.9 50.3 27.1 30.0 54.0 31.1 41.9 57.2 23.2 GRPEL1 "FLJ25609, GrpE, hMGE" ENSG00000109519 "GrpE like 1, mitochondrial" Q9HAV7 4 7058895-7068064 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036647 Supported Supported Mitochondria NA NA 23000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA036647: AB_10672359" "unprognostic (6.13e-3)" "unprognostic (3.66e-2)" "unprognostic (1.92e-2)" "unprognostic (6.31e-2)" "unprognostic (9.77e-2)" "unprognostic (2.12e-3)" "unprognostic (2.17e-1)" "unprognostic (2.21e-3)" "unprognostic (1.51e-1)" "unprognostic (5.53e-2)" "unprognostic (4.99e-2)" "unprognostic (3.86e-2)" "prognostic favorable (2.00e-6)" "unprognostic (9.61e-2)" "unprognostic (7.18e-2)" "unprognostic (2.81e-1)" "unprognostic (7.30e-2)" 15.4 35.9 12.7 7.7 13.2 24.9 11.2 14.2 16.4 7.2 14.2 10.1 9.0 7.0 8.4 10.9 8.4 7.5 23.1 13.1 13.6 20.7 32.4 7.7 10.2 14.0 13.5 10.4 10.1 13.1 6.9 7.8 14.4 7.9 9.7 12.4 8.6 7.9 26.8 10.7 7.8 8.3 13.8 10.4 11.1 12.8 13.7 7.6 8.9 29.7 11.3 15.2 7.6 14.1 21.7 20.0 11.3 22.3 21.3 17.9 13.9 27.9 22.2 30.8 22.6 35.5 27.5 46.4 18.3 21.4 47.7 21.5 45.0 32.0 35.9 11.2 28.2 49.8 17.6 38.7 24.9 50.7 24.2 17.8 41.4 27.3 32.8 15.7 27.4 30.8 29.7 18.9 36.7 21.9 40.3 62.5 16.9 38.8 65.7 26.6 42.1 19.5 31.0 22.4 31.6 15.3 21.9 21.5 24.3 11.4 19.3 29.2 23.8 20.5 12.7 29.5 49.3 20.3 31.1 31.0 27.9 32.6 16.5 12.0 25.2 41.1 22.8 27.6 31.9 27.3 24.4 25.9 36.3 21.6 30.8 23.9 8.4 26.2 22.7 22.0 26.6 27.2 12.7 13.2 14.2 16.4 13.1 13.6 14.0 13.5 14.4 13.8 13.7 14.1 52.5 25.6 32.1 1.6 40.7 133.4 134.8 68.5 60.9 27.8 44.0 43.6 96.1 34.3 43.1 38.6 10.4 69.3 52.9 35.3 133.1 75.0 60.3 35.0 41.7 51.5 18.5 34.5 4.5 47.7 80.3 46.5 26.0 38.0 58.2 23.2 25.0 109.4 60.3 28.6 5.1 34.1 52.9 29.0 74.7 84.9 28.0 41.7 64.0 2.8 54.0 26.4 17.5 3.0 6.5 91.4 27.6 29.0 27.0 116.5 49.2 203.1 36.2 28.0 0.0 38.1 56.3 51.7 55.0 58.1 125.2 86.1 61.6 92.0 47.0 120.3 GTF2H5 "bA120J8.2, C6orf175, FLJ30544, TFB5, TFIIH, TTD, TTD-A, TTDA" ENSG00000272047 "General transcription factor IIH subunit 5" Q6ZYL4 6 158168350-158199344 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 425.8;Proximal tubular cells: 504.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.04e-2)" "unprognostic (2.02e-2)" "unprognostic (2.50e-1)" "unprognostic (8.59e-3)" "unprognostic (3.56e-1)" "unprognostic (1.03e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "unprognostic (5.22e-3)" "prognostic unfavorable (6.11e-4)" "unprognostic (3.13e-1)" "unprognostic (8.46e-2)" "unprognostic (3.58e-3)" "unprognostic (1.33e-2)" 18.0 21.5 18.9 8.3 20.7 5.1 14.1 19.0 32.5 9.1 17.9 9.6 7.4 8.0 20.8 10.1 10.7 7.8 14.0 19.7 20.1 17.7 21.8 7.7 9.9 19.3 18.7 10.2 11.3 13.5 3.2 8.3 19.6 12.7 7.8 18.2 9.0 10.8 27.7 7.2 8.2 9.6 19.7 9.2 8.9 15.1 19.3 15.4 8.4 18.1 9.8 11.3 3.1 21.3 18.5 14.6 24.3 27.5 32.2 40.7 20.8 30.2 26.4 24.7 30.4 10.2 17.4 20.6 48.5 29.6 42.7 13.7 12.0 29.4 29.3 26.6 33.3 28.1 16.1 44.2 29.4 16.1 14.4 36.2 30.2 23.8 29.0 48.5 19.9 29.3 34.3 14.7 46.7 11.1 24.7 39.1 25.2 23.2 17.3 15.6 15.1 32.4 50.3 16.2 18.4 14.7 26.9 26.1 27.0 31.0 21.6 38.1 31.8 18.4 22.5 25.5 39.4 14.1 16.9 30.0 37.1 15.3 38.0 11.6 23.8 16.9 25.4 31.1 22.4 32.7 27.9 25.9 30.6 27.8 33.0 31.7 5.6 31.9 33.4 41.9 35.9 24.3 18.9 20.7 19.0 32.5 19.7 20.1 19.3 18.7 19.6 19.7 19.3 21.3 79.5 44.8 58.4 16.6 49.6 45.5 113.4 232.9 46.1 45.7 91.3 122.2 86.8 88.6 130.4 141.6 16.7 187.8 62.9 44.6 418.7 130.1 425.8 207.5 76.0 61.8 46.6 33.7 15.6 122.4 167.4 93.0 54.0 120.6 65.2 126.7 92.4 180.4 162.0 47.1 18.7 75.1 166.8 80.0 49.2 103.3 112.5 80.3 80.0 11.2 120.6 120.5 117.4 14.1 25.9 92.1 52.7 110.2 24.6 94.3 71.2 504.1 205.0 50.2 72.3 71.8 87.7 227.3 130.6 98.4 63.1 132.8 57.8 177.5 76.1 127.2 H1-2 "H1.2, H1c, H1F2, H1s-1, HIST1H1C" ENSG00000187837 "H1.2 linker histone, cluster member" P16403 6 26055740-26056470 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 49.3;Cytotrophoblasts: 42.7;Extravillous trophoblasts: 68.1;Hofbauer cells: 75.5;Syncytiotrophoblasts: 298.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 258.6;eosinophil: 458.7;neutrophil: 229.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 458.7" "Cell line enhanced" "Detected in many" "K-562: 334.2;SiHa: 311.1;U-2 OS: 601.6;U-266/70: 673.7;U-266/84: 661.8" "Low region specificity" "Detected in all" "CAB011507, HPA055907" Supported Supported "Nucleoplasm,Nucleoli rim" NA NA 5500000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli rim" "CAB011507: AB_2117984, HPA055907: AB_2682966" "unprognostic (4.43e-2)" "unprognostic (1.57e-3)" "unprognostic (1.31e-2)" "unprognostic (2.96e-2)" "unprognostic (5.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.96e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.85e-1)" "unprognostic (8.93e-2)" "unprognostic (3.08e-1)" "prognostic favorable (8.06e-5)" 72.2 47.6 67.1 27.2 55.3 229.5 71.7 148.8 64.2 116.1 84.5 54.5 33.6 14.6 42.0 70.3 41.3 18.9 154.7 51.1 60.1 236.3 130.0 60.5 31.5 64.6 70.4 89.4 60.5 8.7 15.2 43.8 56.7 132.9 44.2 22.0 39.8 16.4 227.4 65.0 42.8 7.9 57.4 56.6 73.4 26.8 71.4 62.0 59.7 99.1 27.8 29.5 90.6 76.7 39.9 27.5 20.5 21.9 49.9 10.0 0.7 19.5 30.8 87.9 92.6 14.9 28.1 3.1 109.6 25.6 32.8 17.3 6.4 15.0 24.3 38.7 23.4 16.5 27.8 17.5 14.7 7.8 38.4 70.4 19.9 11.5 19.2 27.3 13.8 17.6 334.2 243.3 43.7 17.3 20.8 18.3 11.5 96.3 41.4 10.8 9.5 129.1 52.8 28.1 52.6 17.9 311.1 53.0 22.0 19.1 65.8 12.5 6.8 41.1 601.6 12.5 9.0 673.7 661.8 31.3 29.9 253.6 14.4 258.6 14.3 458.7 19.3 14.2 24.4 57.7 31.9 21.4 30.5 76.8 29.4 23.1 229.3 20.2 18.9 31.6 48.3 22.1 67.1 55.3 148.8 64.2 51.1 60.1 64.6 70.4 56.7 57.4 71.4 76.7 14.9 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 0.0 0.0 42.7 29.2 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 68.1 9.4 0.0 0.0 0.0 0.0 0.0 0.0 75.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 298.4 4.5 0.0 0.0 0.0 H3C6 "H3.1, H3/d, H3FD, HIST1H3E" ENSG00000274750 "H3 clustered histone 6" P68431 6 26224199-26227473 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Hofbauer cells: 1.0;Syncytiotrophoblasts: 1.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 10.5;hTERT-RPE1: 7.5;SCLC-21H: 11.9;T-47d: 7.3" "Low region specificity" "Detected in all" HPA042570 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA042570: AB_2678056" "unprognostic (2.42e-2)" "unprognostic (1.78e-1)" "unprognostic (1.78e-3)" "unprognostic (9.07e-2)" "unprognostic (1.34e-1)" "unprognostic (3.65e-1)" "unprognostic (1.23e-1)" "unprognostic (3.90e-1)" "unprognostic (1.83e-1)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (7.66e-2)" 0.6 3.5 1.0 1.0 1.5 0.4 1.8 3.9 3.2 1.2 2.7 2.9 4.7 0.8 4.9 2.8 1.5 1.0 6.0 1.1 1.5 1.6 2.9 0.5 1.3 2.0 1.7 1.0 0.7 1.5 0.6 0.9 2.4 3.4 1.9 0.2 1.9 0.7 5.1 1.2 4.7 0.4 1.9 2.2 2.6 1.4 1.4 1.2 2.6 3.7 0.9 1.2 1.2 3.4 1.9 2.0 2.8 1.3 3.3 1.6 0.2 1.3 1.5 0.7 0.5 0.6 1.1 0.0 10.5 0.5 1.0 2.3 0.0 0.3 0.6 2.9 2.5 0.4 1.0 0.6 1.0 0.1 1.7 2.3 2.4 0.3 0.7 7.5 1.1 0.2 0.3 2.2 1.9 1.8 0.4 0.1 0.2 1.4 1.9 1.4 0.6 0.3 5.7 1.1 11.9 1.4 1.9 3.0 3.4 0.4 7.3 1.2 0.6 1.3 0.4 0.4 0.3 0.8 0.3 0.2 0.6 0.1 0.7 0.2 0.7 0.0 0.5 0.6 0.7 0.5 0.7 0.7 0.5 0.9 0.6 0.7 2.7 0.2 0.6 1.7 1.3 0.5 1.0 1.5 3.9 3.2 1.1 1.5 2.0 1.7 2.4 1.9 1.4 3.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1167.5;Distal tubular cells: 520.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 127.0 224.7 120.6 51.1 135.4 58.8 91.3 146.4 138.1 65.2 128.0 110.7 224.2 55.9 73.7 101.3 68.8 64.3 793.3 109.0 138.1 231.4 324.8 64.7 54.9 135.9 141.6 78.4 83.7 209.5 48.1 65.6 139.6 77.1 113.2 63.0 104.8 75.0 950.6 74.4 184.4 79.0 141.4 75.8 109.0 67.1 143.3 53.1 90.8 1097.1 62.5 89.2 64.1 152.8 108.2 83.2 56.6 102.2 342.1 190.1 57.9 89.0 134.6 89.0 86.8 100.5 101.7 53.9 60.8 145.3 100.1 82.8 95.2 124.8 109.2 121.1 83.1 123.6 44.9 194.2 145.9 100.6 90.0 183.7 201.6 92.7 149.0 151.0 168.2 81.0 105.2 83.9 189.5 78.0 57.1 190.7 39.8 160.2 89.0 61.7 188.3 103.2 183.3 148.9 27.2 93.7 151.7 169.8 239.5 68.5 105.4 177.9 118.0 83.5 86.9 79.3 65.1 62.6 101.1 94.7 95.5 158.4 84.4 95.7 168.1 66.4 45.2 150.3 57.6 65.5 61.3 56.6 154.2 49.7 55.8 51.3 72.7 88.2 123.3 51.8 94.7 135.6 120.6 135.4 146.4 138.1 109.0 138.1 135.9 141.6 139.6 141.4 143.3 152.8 106.5 48.1 36.5 63.0 48.3 62.1 136.5 183.3 49.5 29.3 49.5 52.3 1167.5 104.4 107.7 97.5 56.3 227.9 42.4 129.5 520.4 124.0 93.4 59.5 49.0 75.2 74.9 85.2 32.7 57.2 75.2 79.5 53.0 60.2 62.8 94.2 69.9 277.6 139.6 13.5 33.0 93.4 114.0 98.1 67.4 99.7 56.5 78.1 88.9 27.2 110.2 65.0 32.0 35.2 47.5 58.4 134.8 62.8 37.1 60.5 376.0 321.1 73.5 80.0 72.3 72.9 80.7 120.4 49.4 53.8 54.7 186.6 45.2 194.0 113.5 110.3 HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827157 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 378.7;Proximal tubular cells: 501.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved NA NA 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA043041: AB_2678284, HPA061143: AB_2684439" "unprognostic (3.11e-1)" "prognostic favorable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favorable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favorable (5.19e-4)" 41.2 109.0 81.5 20.2 84.2 82.1 35.1 82.7 103.9 22.8 78.9 53.7 45.3 24.6 31.1 29.0 28.5 21.9 138.6 89.9 83.8 100.1 236.2 39.2 24.6 82.8 80.2 22.0 63.5 54.0 72.7 23.1 83.7 33.5 23.3 32.2 32.5 37.7 198.8 31.2 44.8 24.7 80.1 35.2 52.9 91.7 84.0 35.8 35.1 156.2 18.4 34.8 24.6 87.6 31.1 46.1 40.9 46.5 35.1 13.8 37.0 38.1 35.2 57.7 46.1 23.7 26.5 6.4 76.5 32.9 39.6 33.2 39.1 38.2 17.2 64.5 63.4 12.0 47.9 69.3 50.2 15.7 62.6 16.9 80.6 28.8 19.6 50.6 50.1 79.8 16.1 56.3 18.3 51.2 41.1 34.0 15.7 32.0 42.3 34.2 25.8 73.6 74.5 13.8 54.7 47.4 41.8 52.9 84.9 30.8 38.7 52.0 38.7 17.5 21.5 36.9 44.6 63.3 64.7 19.8 29.8 14.5 28.5 37.3 33.3 64.9 26.0 59.1 19.0 31.3 34.0 27.3 30.7 30.4 32.0 27.4 29.7 25.5 88.2 64.8 42.8 30.3 81.5 84.2 82.7 103.9 89.9 83.8 82.8 80.2 83.7 80.1 84.0 87.6 46.2 9.6 39.0 11.8 33.7 23.8 45.1 59.7 12.0 117.1 39.5 31.1 84.2 65.8 39.7 46.0 64.6 52.4 43.2 60.9 158.5 45.6 193.1 75.0 12.1 35.3 39.6 378.7 24.6 38.3 38.5 25.6 23.9 35.5 30.4 36.0 41.0 186.9 76.2 138.0 22.2 41.2 93.6 49.0 41.6 60.1 46.9 47.6 55.2 12.2 50.1 95.2 64.9 7.1 19.7 49.7 68.8 54.9 50.4 48.3 168.9 501.7 70.2 117.0 72.3 33.3 61.1 245.2 68.3 29.1 45.6 68.7 44.1 45.3 39.9 49.9 HAX1 "HAX-1, HCLSBP1, HS1BP1" ENSG00000143575 "HCLS1 associated protein X-1" O00165 1 154272589-154275875 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055141, HPA075289" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055141: AB_2682714, HPA075289: AB_2686742" "unprognostic (1.32e-1)" "unprognostic (2.68e-1)" "unprognostic (9.50e-2)" "unprognostic (6.93e-2)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (1.55e-3)" "unprognostic (2.34e-1)" "unprognostic (2.20e-1)" "unprognostic (9.09e-3)" "unprognostic (3.09e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.52e-1)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.96e-1)" 58.6 63.0 100.0 43.6 105.5 36.8 74.4 105.2 124.1 60.0 100.6 62.0 48.0 46.2 100.1 53.7 61.7 40.4 168.6 100.5 107.9 76.1 104.0 45.2 58.3 102.1 99.9 72.9 85.5 84.9 88.6 40.5 102.9 55.5 63.3 54.1 85.8 63.8 256.7 48.8 43.2 64.1 105.1 47.1 66.3 69.5 105.0 67.4 69.2 242.7 77.3 58.5 48.9 103.3 115.3 100.7 84.2 178.0 100.3 111.8 132.1 109.8 178.7 227.0 207.5 126.6 125.7 170.9 150.7 188.0 105.9 100.0 190.7 151.3 172.3 171.0 140.8 81.8 76.5 104.4 221.5 172.5 167.0 104.4 274.2 172.8 206.3 82.2 129.7 246.1 166.1 244.8 145.6 260.9 169.9 136.1 88.7 277.4 213.2 121.3 59.7 326.7 115.4 60.8 123.2 121.7 96.4 228.2 326.7 137.5 190.0 454.8 64.5 92.7 122.7 97.7 148.8 284.8 315.9 315.3 139.0 158.4 153.4 266.5 97.6 215.4 113.7 121.9 129.3 136.1 139.2 128.3 118.6 142.2 166.5 132.6 61.1 116.7 150.1 122.8 183.3 163.9 100.0 105.5 105.2 124.1 100.5 107.9 102.1 99.9 102.9 105.1 105.0 103.3 69.9 28.9 37.6 7.2 125.2 74.6 112.2 118.8 60.9 57.0 92.8 123.1 106.9 62.9 71.6 46.0 47.9 84.8 76.1 54.1 181.9 93.3 147.6 41.3 36.6 65.6 57.6 66.0 12.0 106.4 132.1 62.2 36.7 34.0 99.6 80.6 61.4 90.3 98.7 40.4 12.9 67.1 91.6 63.9 79.3 104.6 61.2 66.8 87.2 9.4 128.5 91.1 91.6 7.5 17.1 84.6 63.6 62.1 192.9 92.5 128.7 141.8 59.3 97.5 59.2 58.2 76.0 223.8 112.0 71.0 76.4 88.8 97.7 74.3 71.7 101.7 HDDC2 "C6orf74, CGI-130, dJ167O5.2" ENSG00000111906 "HD domain containing 2" Q7Z4H3 6 125219962-125302078 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 338.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035677 Approved Approved Nucleoplasm,Nucleoli NA NA 44000 "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA035677: AB_10603768" "unprognostic (8.34e-2)" "unprognostic (5.41e-2)" "unprognostic (6.52e-2)" "unprognostic (6.25e-2)" "unprognostic (2.78e-2)" "unprognostic (6.39e-3)" "unprognostic (1.04e-3)" "unprognostic (1.76e-1)" "unprognostic (2.18e-1)" "unprognostic (2.38e-2)" "unprognostic (8.59e-3)" "unprognostic (5.13e-2)" "unprognostic (4.56e-2)" "unprognostic (2.54e-1)" "unprognostic (3.68e-2)" "unprognostic (1.80e-2)" "unprognostic (9.54e-2)" 47.4 84.4 58.0 20.1 65.9 19.7 42.1 59.5 98.5 47.2 78.4 38.8 20.3 36.2 29.6 49.7 37.0 15.1 82.3 60.8 64.5 75.6 22.9 31.9 27.1 65.1 66.8 41.1 44.5 49.4 50.0 15.7 63.0 38.5 22.1 31.5 45.8 23.8 118.1 39.0 30.6 13.6 60.8 27.6 43.7 58.7 61.6 22.2 40.3 60.7 24.8 39.2 39.5 60.7 29.7 81.2 46.2 191.3 23.0 30.8 59.7 36.4 41.4 30.9 33.1 122.7 30.4 119.9 80.8 57.4 89.0 26.5 53.1 41.1 36.5 46.7 166.8 55.2 43.6 125.1 65.0 76.6 45.3 56.0 61.8 49.6 104.6 44.6 20.2 67.8 205.1 51.4 59.5 162.7 61.2 73.8 57.7 79.9 58.8 92.8 37.2 25.2 68.7 34.1 84.0 44.5 43.9 84.8 88.8 35.4 50.2 126.6 18.2 37.7 44.5 58.8 75.8 72.1 48.2 110.1 56.0 122.6 80.4 13.8 33.4 6.7 53.3 30.6 43.8 71.2 57.7 72.6 36.1 59.4 71.3 78.2 7.3 62.1 29.0 38.3 55.7 44.0 58.0 65.9 59.5 98.5 60.8 64.5 65.1 66.8 63.0 60.8 61.6 60.7 23.0 25.6 41.2 22.5 39.3 44.6 64.3 114.9 70.6 62.6 73.5 114.4 119.9 37.1 55.3 62.5 14.6 86.6 56.0 35.0 338.5 86.0 61.3 50.9 60.7 24.2 64.5 33.4 17.1 98.0 156.4 67.5 33.6 37.5 38.0 84.8 9.3 21.3 112.2 69.0 17.9 76.4 77.3 54.2 20.4 42.1 91.0 34.6 80.0 15.0 31.7 90.5 155.5 19.1 10.6 58.5 45.3 114.7 47.4 101.9 72.3 254.8 38.9 25.0 39.5 83.9 72.6 124.5 74.6 88.6 43.0 45.7 47.6 145.8 84.1 57.9 HIGD1A "DKFZP564K247, HIG1, RCF1A" ENSG00000181061 "HIG1 hypoxia inducible domain family member 1A" Q9Y241 3 42782908-42804490 "Predicted membrane proteins" "Electron transport, Respiratory chain, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 638.8;Distal tubular cells: 632.0;Paneth cells: 610.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 509.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043336 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA043336: AB_10795039" "unprognostic (6.46e-2)" "unprognostic (3.72e-3)" "prognostic favorable (2.12e-4)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (3.53e-1)" "unprognostic (3.70e-1)" "unprognostic (8.45e-2)" "unprognostic (6.14e-2)" "unprognostic (2.94e-1)" "unprognostic (1.24e-1)" "unprognostic (8.94e-2)" "prognostic favorable (3.99e-8)" "unprognostic (7.37e-2)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" 121.3 130.0 134.6 75.3 140.6 53.8 81.4 151.4 198.8 90.2 135.4 295.2 162.2 65.9 95.2 162.8 62.6 79.3 323.1 139.4 155.1 198.9 343.5 66.5 50.9 148.1 148.8 39.4 60.8 111.4 90.5 64.6 153.5 101.5 300.1 152.7 75.1 96.3 174.2 68.8 134.8 96.2 156.1 48.9 145.9 63.7 145.6 52.8 115.5 316.7 80.0 99.5 120.1 174.0 159.9 67.0 182.9 165.2 420.3 244.3 195.2 205.1 151.0 168.4 165.8 132.8 166.7 95.8 120.5 161.8 114.0 92.9 143.0 203.0 225.6 135.5 145.9 301.0 127.6 257.4 191.8 180.4 131.4 274.0 233.7 129.0 181.4 94.7 159.8 135.1 299.7 110.3 247.3 51.1 96.1 61.1 162.7 133.7 176.5 80.9 138.0 72.1 454.1 361.1 82.7 108.2 187.6 142.0 207.0 182.9 145.0 130.0 166.1 127.4 105.2 341.1 219.1 89.7 184.1 207.2 165.2 185.7 100.6 115.7 66.2 130.5 72.9 115.4 65.8 56.6 71.5 73.6 77.2 43.6 60.3 70.5 70.0 65.6 143.2 509.4 99.4 171.5 134.6 140.6 151.4 198.8 139.4 155.1 148.1 148.8 153.5 156.1 145.6 174.0 50.1 54.5 82.4 32.3 39.7 131.2 153.1 244.8 59.2 35.7 86.4 62.0 351.5 80.1 133.0 138.0 10.4 114.1 99.5 638.8 632.0 113.3 8.4 87.3 41.2 50.8 82.0 126.8 32.8 145.0 202.7 98.1 100.9 63.6 93.3 49.7 59.6 197.9 77.1 28.6 27.3 193.5 343.8 46.9 113.3 13.0 30.7 63.4 176.1 21.5 82.7 232.5 43.3 14.1 32.9 279.4 610.7 52.3 65.5 193.5 122.4 296.4 106.0 41.2 78.9 28.8 119.8 186.1 78.7 94.2 204.6 299.9 50.7 101.5 168.0 254.2 HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 32: Non-specific - Translation" Mitochondria Cytosol "HPA042715: AB_2678127" "unprognostic (9.24e-2)" "unprognostic (6.31e-3)" "unprognostic (7.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (1.98e-2)" "unprognostic (3.11e-3)" "unprognostic (9.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.09e-2)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" 146.1 175.6 143.3 87.0 146.2 133.1 113.5 147.2 175.0 104.7 168.0 199.4 118.9 111.7 51.3 130.0 105.0 80.5 318.7 139.8 146.0 182.7 163.3 95.7 132.9 143.9 142.2 118.7 108.7 204.9 125.1 54.6 141.6 127.9 96.3 45.5 163.2 92.7 422.5 140.8 136.6 68.1 145.3 129.3 148.6 66.0 149.0 110.7 114.0 297.9 92.7 152.3 105.2 145.7 104.9 166.6 99.0 172.6 98.5 186.4 262.2 66.6 109.7 164.7 206.4 176.0 202.2 183.3 149.9 107.1 214.2 127.3 146.2 260.6 65.9 424.0 234.0 92.6 161.7 244.7 137.4 149.7 230.1 238.2 213.2 93.7 113.3 126.3 141.7 146.5 104.0 341.5 124.0 315.9 165.3 178.1 124.8 195.5 181.7 157.1 75.6 324.7 265.5 158.7 107.9 141.5 71.4 295.2 310.5 100.7 173.3 233.7 96.8 118.5 124.7 110.2 142.5 165.2 216.6 158.4 150.5 254.1 77.5 284.2 743.6 219.8 391.2 975.8 389.5 618.1 540.1 452.6 930.0 496.0 488.1 464.2 124.6 308.0 1024.9 616.8 621.8 971.3 143.3 146.2 147.2 175.0 139.8 146.0 143.9 142.2 141.6 145.3 149.0 145.7 100.4 73.7 78.6 0.0 212.5 232.2 332.8 358.0 272.0 60.5 225.5 288.5 145.3 174.5 191.0 182.1 12.5 223.0 184.2 415.6 534.1 204.5 83.9 140.0 120.6 110.9 266.6 90.8 0.0 237.3 185.4 129.1 142.2 124.2 130.0 157.0 120.3 217.0 378.7 65.6 0.0 450.7 219.7 458.8 345.2 56.8 140.1 292.1 257.9 0.0 449.7 138.1 230.7 0.0 0.0 110.0 493.0 85.0 184.2 292.6 313.8 542.8 142.3 47.7 118.3 145.9 138.8 96.7 79.4 301.8 225.0 280.2 223.7 182.1 385.3 532.4 HIKESHI "C11orf73, HSPC138, HSPC179, OPI10" ENSG00000149196 "Heat shock protein nuclear import factor hikeshi" Q53FT3 11 86302211-86345943 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Extravillous trophoblasts: 146.2;Hofbauer cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012708, HPA035063, HPA035064" Approved Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "Nucleoplasm, Nuclear bodies" "HPA012708: , HPA035063: AB_10601143, HPA035064: AB_2674441" "unprognostic (1.10e-3)" "unprognostic (5.09e-2)" "unprognostic (1.92e-1)" "unprognostic (2.40e-2)" "unprognostic (1.50e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (8.81e-4)" "unprognostic (9.92e-2)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (8.24e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (4.01e-12)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.33e-3)" "unprognostic (1.71e-1)" 34.7 27.0 46.1 17.8 46.7 19.0 31.4 47.8 71.5 33.9 44.5 40.8 10.4 32.3 24.7 33.4 31.0 15.0 57.1 46.1 47.2 17.0 24.7 23.9 26.0 46.6 46.0 37.5 22.8 22.9 31.5 28.3 47.1 24.5 19.1 32.5 19.8 28.6 59.9 29.5 20.8 31.1 49.1 28.5 23.5 19.0 47.1 32.9 17.7 57.8 30.8 32.8 31.8 50.9 28.6 30.5 72.7 40.5 59.9 74.2 38.2 43.2 52.0 44.2 52.6 90.8 77.8 29.0 96.9 57.4 83.9 59.9 54.2 95.1 47.0 62.0 47.6 47.0 47.5 68.2 80.8 58.0 36.8 52.7 94.9 52.8 62.5 56.9 85.9 54.7 51.1 64.6 91.5 78.0 69.6 136.7 59.5 186.3 20.1 53.0 35.7 65.4 77.2 53.2 44.8 38.7 53.8 39.8 31.1 72.7 64.1 38.5 44.2 52.1 36.4 105.8 32.7 27.7 68.3 57.6 26.6 54.4 52.6 47.8 53.4 44.4 48.6 52.5 54.3 61.8 59.1 53.6 68.9 52.9 51.1 52.3 11.2 57.9 53.9 53.7 84.5 43.2 46.1 46.7 47.8 71.5 46.1 47.2 46.6 46.0 47.1 49.1 47.1 50.9 59.9 38.5 32.1 0.0 16.1 0.0 0.0 0.0 0.0 0.0 53.4 81.3 0.0 0.0 14.9 27.6 0.0 129.6 28.7 0.0 41.1 76.1 0.0 41.4 60.4 28.7 0.0 0.0 0.0 66.3 146.2 30.2 0.0 36.8 22.7 52.1 0.0 0.0 94.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 0.0 50.1 0.0 0.0 0.0 0.0 49.8 0.0 0.0 4.1 0.0 0.0 43.2 27.7 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 77.6 18.1 59.3 0.0 0.0 HINT1 "HINT, PKCI-1, PRKCNH1" ENSG00000169567 "Histidine triad nucleotide binding protein 1" P49773 5 131155383-131224468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 3537.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044577 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Plasma membrane" "HPA044577: AB_10795618" "unprognostic (2.00e-1)" "unprognostic (9.27e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (8.30e-3)" "unprognostic (2.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.49e-2)" "unprognostic (6.50e-3)" "unprognostic (4.43e-2)" "unprognostic (4.39e-3)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (3.68e-1)" 132.6 175.0 235.7 139.8 245.1 259.3 172.7 241.6 326.2 117.6 243.8 227.6 176.1 119.6 187.5 181.3 165.6 108.0 167.2 245.9 247.8 256.7 474.2 119.0 206.5 241.6 237.2 121.5 165.5 285.6 152.5 87.5 249.1 155.1 226.5 110.8 172.8 116.4 334.1 170.0 196.3 124.2 242.6 126.9 136.5 80.1 240.8 166.5 177.2 278.4 192.3 152.9 129.7 245.3 437.1 522.7 448.2 877.2 273.1 297.1 441.3 300.3 230.9 235.4 272.1 547.1 516.8 563.3 625.7 329.6 569.1 253.4 315.4 635.3 244.1 500.0 514.6 199.1 814.0 771.9 532.6 349.4 65.4 400.1 618.6 295.8 528.2 533.7 314.1 727.8 313.4 1132.1 338.8 419.9 548.0 945.6 415.6 425.6 362.0 407.9 436.1 988.1 500.6 567.0 563.3 351.9 380.5 243.5 612.0 574.4 291.2 520.8 396.0 351.7 244.0 323.0 684.2 342.3 561.4 578.8 497.8 586.8 346.3 179.8 187.9 85.0 196.3 109.9 298.0 384.9 462.0 294.2 396.9 332.6 416.0 325.5 35.6 269.0 128.0 521.4 362.5 608.6 235.7 245.1 241.6 326.2 245.9 247.8 241.6 237.2 249.1 242.6 240.8 245.3 582.7 282.0 279.1 34.3 718.2 1301.2 1472.2 1928.1 889.5 191.2 1134.3 1831.1 517.0 1028.0 882.2 715.4 45.9 780.9 641.6 1245.1 1663.0 1024.5 783.0 718.9 443.7 501.2 698.1 669.7 53.8 774.3 1632.8 400.2 355.2 753.7 108.2 666.5 436.2 2380.1 887.1 148.0 48.0 947.2 915.5 472.4 906.9 206.3 392.4 447.0 965.8 34.7 1269.4 405.1 488.1 26.7 55.4 894.3 1094.2 418.6 679.7 1998.9 1690.3 3537.5 708.3 194.0 243.3 287.0 730.3 625.5 197.9 1109.1 1146.1 456.8 671.1 464.3 1280.4 1713.2 HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 633.9;Hepatocytes: 457.4;Proximal tubular cells: 578.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" 50.8 79.5 41.7 15.5 43.9 27.0 48.5 44.9 46.8 23.2 40.3 42.6 34.9 25.9 48.6 27.5 29.9 14.9 87.4 39.8 43.1 91.1 169.2 30.2 21.0 43.8 42.5 19.2 65.9 72.6 41.2 17.6 42.0 33.9 34.2 20.4 39.7 26.1 80.1 33.4 34.2 20.1 43.9 33.8 56.9 29.8 47.3 38.8 38.4 85.5 23.8 30.6 24.2 44.0 30.3 76.1 47.1 45.6 29.0 24.3 33.2 27.8 39.2 42.3 46.1 49.9 31.1 39.9 31.7 25.3 59.8 29.3 21.2 40.9 44.1 87.8 40.7 42.2 64.1 45.8 68.1 25.1 40.0 27.3 36.8 40.2 64.8 16.7 33.2 91.4 25.5 117.4 34.0 60.3 61.3 31.3 21.4 70.0 138.7 60.8 33.1 53.6 61.5 21.5 38.4 46.4 36.0 42.7 49.6 27.5 45.9 44.6 16.5 22.0 37.7 30.4 35.7 107.0 127.3 57.4 49.8 32.2 36.2 41.0 77.5 4.7 68.9 58.5 62.4 98.9 73.7 69.8 113.4 96.7 56.4 58.6 7.6 66.8 56.9 246.1 107.3 81.2 41.7 43.9 44.9 46.8 39.8 43.1 43.8 42.5 42.0 43.9 47.3 44.0 49.3 22.4 17.5 5.2 57.9 45.4 63.4 137.6 49.5 39.8 99.1 105.8 115.1 130.1 68.3 80.9 20.9 154.9 69.3 148.2 633.9 115.5 67.3 83.9 28.6 47.8 96.0 100.8 1.7 172.1 71.7 53.2 52.5 44.6 18.4 43.5 63.1 457.4 113.9 20.2 2.5 127.4 126.1 61.1 51.4 128.0 40.4 47.7 120.9 1.9 74.1 123.7 87.6 1.5 4.5 85.6 157.5 44.8 77.7 40.7 181.4 578.1 105.1 45.5 46.0 54.2 72.6 38.4 77.4 64.7 45.9 56.8 51.0 85.1 126.7 84.8 HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Nuclear bodies" "HPA028069: AB_10601815" "unprognostic (2.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.61e-1)" "unprognostic (5.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (7.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" 57.8 21.5 29.5 25.3 31.5 23.3 35.1 32.9 23.4 27.6 75.9 30.7 16.7 33.1 24.2 30.9 31.7 30.6 53.7 19.9 42.1 38.2 29.8 26.9 22.8 35.5 36.2 27.2 25.8 46.7 12.8 34.7 27.8 23.3 20.6 22.4 22.9 26.1 69.0 22.3 20.2 39.3 34.2 30.6 22.1 18.9 43.1 25.5 33.7 85.3 24.7 32.3 22.4 33.0 19.3 18.0 13.4 15.1 60.5 37.9 12.9 20.0 23.1 15.9 13.3 19.9 13.8 20.7 16.3 24.4 8.0 24.3 10.2 22.2 22.1 30.8 15.8 21.0 20.3 15.2 25.0 22.9 12.8 35.8 42.8 6.1 17.7 16.5 19.4 14.8 6.4 40.4 26.0 10.1 19.2 15.8 3.4 17.3 11.1 25.4 47.3 19.9 26.4 29.4 2.0 11.3 27.1 30.7 18.7 14.2 34.6 41.2 25.8 24.8 16.9 28.9 14.6 21.7 37.2 21.4 11.9 23.5 23.7 10.6 12.7 6.1 4.0 9.4 5.0 2.8 3.6 4.3 14.0 3.3 3.2 4.0 21.1 4.4 11.1 1.7 4.0 5.0 29.5 31.5 32.9 23.4 19.9 42.1 35.5 36.2 27.8 34.2 43.1 33.0 122.2 12.8 44.7 46.0 29.6 66.5 42.8 21.3 39.3 16.2 35.8 25.8 159.9 37.1 32.9 33.1 18.8 18.6 31.2 32.7 5.9 13.0 21.8 76.5 80.5 96.5 37.1 20.6 44.9 24.9 13.4 59.2 23.0 49.0 14.5 24.3 57.5 53.2 30.7 32.0 48.0 28.4 12.2 102.0 76.0 26.1 42.9 68.1 58.7 73.1 69.1 16.2 25.7 45.8 69.1 21.5 21.1 37.6 24.9 52.6 40.7 35.0 65.4 24.9 52.6 83.4 56.4 10.7 8.1 33.4 75.0 15.5 29.8 12.5 25.2 51.2 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HMGN3 TRIP7 ENSG00000118418 "High mobility group nucleosomal binding domain 3" Q15651 6 79201245-79234738 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018370, HPA027971, HPA063572" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Cytosol "CAB018370: , HPA027971: AB_1850808, HPA063572: AB_2732703" "unprognostic (1.02e-1)" "unprognostic (2.04e-2)" "unprognostic (5.92e-2)" "unprognostic (5.26e-2)" "unprognostic (3.48e-1)" "unprognostic (3.88e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.76e-4)" "unprognostic (8.78e-2)" "unprognostic (5.31e-3)" "unprognostic (1.47e-3)" "unprognostic (5.81e-2)" "prognostic unfavorable (1.02e-7)" "unprognostic (1.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.69e-1)" "unprognostic (6.43e-3)" 92.4 174.4 132.9 69.5 136.2 72.8 116.1 141.8 190.4 82.2 153.6 100.6 90.4 93.6 168.6 95.1 209.3 82.8 227.2 132.9 135.8 168.4 147.5 111.5 127.1 139.5 135.2 105.5 90.3 116.7 152.0 114.6 140.8 84.7 73.4 164.6 154.3 68.0 151.4 81.1 74.1 76.1 136.6 91.5 106.9 83.2 133.7 112.7 113.2 130.1 109.9 77.1 81.9 145.6 101.7 90.3 309.7 135.0 121.9 99.6 70.1 69.0 73.7 75.6 110.3 508.3 83.9 1.2 124.2 56.5 101.0 63.4 203.6 78.3 74.2 298.7 170.9 355.9 292.3 268.9 78.0 294.9 52.3 121.5 85.4 50.3 27.7 72.9 170.9 74.3 212.3 275.0 123.8 92.9 136.3 564.7 227.8 87.7 224.5 229.7 472.6 103.8 525.3 145.3 126.0 168.5 131.3 149.4 102.4 271.1 85.1 488.6 75.0 20.9 91.7 73.5 155.3 235.3 375.2 1.9 11.8 1.1 103.0 38.3 147.3 13.6 107.8 148.0 95.9 112.9 75.7 92.8 179.2 99.8 88.7 106.8 7.2 142.3 143.9 208.6 90.4 169.3 132.9 136.2 141.8 190.4 132.9 135.8 139.5 135.2 140.8 136.6 133.7 145.6 140.6 96.1 167.9 129.9 110.1 171.1 193.7 516.8 234.5 261.8 301.4 376.3 424.5 231.6 373.7 242.8 75.0 940.6 169.9 35.3 602.6 229.3 72.5 775.8 108.1 166.0 272.9 95.4 115.8 198.6 823.7 165.3 116.2 199.2 109.6 80.9 261.3 256.3 309.7 195.2 105.3 131.1 435.4 186.0 206.5 60.9 187.0 148.4 257.9 58.1 403.3 320.2 198.8 66.9 159.7 107.2 52.4 167.0 211.3 85.3 36.5 852.5 900.3 134.3 144.7 102.4 233.9 26.8 52.0 260.0 149.9 555.3 109.9 232.4 121.5 173.2 HSBP1 ENSG00000230989 "Heat shock factor binding protein 1" O75506 16 83807978-83819737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.27e-2)" "unprognostic (9.23e-2)" "unprognostic (2.22e-1)" "prognostic favorable (5.73e-4)" "unprognostic (1.85e-2)" "unprognostic (3.74e-3)" "unprognostic (1.03e-2)" "unprognostic (3.07e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.96e-4)" "unprognostic (2.00e-1)" "unprognostic (3.00e-1)" "unprognostic (2.84e-3)" "unprognostic (4.39e-2)" "unprognostic (9.48e-2)" "unprognostic (6.81e-2)" "unprognostic (1.70e-2)" 19.6 34.4 34.3 20.5 33.9 12.6 18.7 35.3 39.4 20.4 36.1 20.9 24.9 16.0 12.2 40.4 19.3 8.4 38.4 33.1 37.4 35.2 19.1 18.2 10.3 36.3 34.9 21.6 18.9 32.4 21.8 18.7 36.4 16.6 15.2 21.9 29.7 10.8 40.7 12.5 22.2 13.0 37.2 17.1 21.8 32.9 36.8 19.5 25.1 32.1 14.9 21.1 21.0 38.5 69.1 91.8 124.6 57.5 50.5 44.7 57.9 97.5 47.4 67.6 31.6 77.4 65.7 46.7 96.9 80.3 65.8 66.2 88.3 64.3 60.3 16.8 101.5 35.8 70.9 105.8 41.6 54.3 58.2 44.7 47.1 72.0 39.7 58.1 43.4 35.1 87.8 13.7 52.0 173.4 44.2 65.1 103.8 76.9 67.5 59.7 94.3 22.6 104.4 62.4 85.6 79.7 166.5 34.5 46.9 63.6 119.1 62.9 75.8 86.1 69.8 55.0 70.4 44.6 52.6 186.3 67.5 63.6 96.1 60.9 118.0 158.5 23.4 159.9 25.8 69.1 28.5 26.7 96.2 48.6 26.0 25.0 157.1 31.4 158.1 71.9 43.7 132.7 34.3 33.9 35.3 39.4 33.1 37.4 36.3 34.9 36.4 37.2 36.8 38.5 159.3 157.0 124.8 21.5 79.9 194.6 236.1 694.7 157.1 89.1 239.1 250.3 712.8 140.2 465.6 252.0 20.9 391.1 76.7 233.9 659.3 410.6 364.4 484.6 161.7 183.1 238.9 78.0 16.0 335.7 482.0 231.5 116.2 202.1 68.5 214.2 141.7 161.2 427.1 109.4 23.8 274.7 547.3 223.2 177.0 241.1 219.6 260.9 304.1 15.0 242.4 236.9 76.2 17.6 33.7 440.2 291.0 143.0 90.8 318.7 259.7 562.7 858.5 90.3 118.3 154.1 220.4 685.0 243.5 279.3 207.7 285.4 58.9 282.5 234.4 376.1 HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Hydrolase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 2455.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Approved Nucleoplasm,Vesicles NA Yes 140000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Vesicles "CAB002056: , HPA052504: AB_2681854" "unprognostic (2.28e-3)" "unprognostic (1.19e-3)" "prognostic favorable (6.14e-6)" "unprognostic (1.75e-1)" "unprognostic (1.84e-2)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.65e-3)" "unprognostic (3.82e-1)" "unprognostic (9.64e-2)" "unprognostic (2.93e-1)" "unprognostic (3.22e-1)" "prognostic favorable (3.81e-4)" "unprognostic (2.53e-1)" "unprognostic (1.83e-1)" "unprognostic (2.74e-1)" "unprognostic (7.16e-2)" 539.8 604.9 456.3 542.1 498.1 442.4 448.9 591.6 887.9 326.6 571.4 435.8 506.9 367.3 614.7 554.2 498.5 508.6 892.4 535.1 614.9 850.5 763.2 480.1 685.0 564.8 564.2 421.4 1238.1 593.8 501.9 487.1 620.0 411.2 525.8 531.5 404.1 439.8 1519.0 224.4 453.5 508.4 554.2 520.3 676.7 395.0 559.8 628.6 422.6 1508.5 879.6 866.0 302.4 656.8 1369.6 2077.3 1370.5 1176.5 1259.4 1337.4 1775.6 2730.9 1550.4 3373.2 2004.8 3151.7 1787.3 2318.5 1614.6 1591.9 2337.3 1835.9 4091.6 1027.2 3323.5 1955.4 605.9 2570.4 881.5 1532.0 347.5 2418.0 1757.1 721.8 1594.5 1045.0 320.7 1753.4 1845.6 321.7 2727.8 1147.0 2704.5 1235.5 2507.0 1761.3 2063.2 3463.3 1874.0 2214.4 962.2 1281.3 1665.1 1008.4 1371.8 1023.9 1980.4 2110.5 763.6 1491.1 1837.1 901.9 1767.0 1621.1 1246.1 1404.5 2402.7 740.6 1985.0 1890.9 1791.1 3316.9 1970.0 517.7 592.3 587.8 1245.4 1159.8 1499.6 1009.2 1441.8 1366.1 656.1 752.2 1367.5 1326.5 201.8 1110.7 1255.0 465.5 1761.7 3439.4 456.3 498.1 591.6 887.9 535.1 614.9 564.8 564.2 620.0 554.2 559.8 656.8 795.5 192.3 228.2 72.5 576.3 282.3 2455.6 315.3 507.6 206.7 454.5 380.1 396.3 278.8 352.8 130.6 127.2 926.1 740.3 513.1 528.3 589.0 49.8 404.1 380.1 512.8 519.8 551.7 33.4 628.8 1032.6 609.7 366.0 366.5 434.8 633.8 249.9 223.9 810.9 181.7 45.6 511.1 303.2 359.8 1060.8 58.2 222.4 590.6 528.3 35.6 530.9 307.4 639.5 28.1 50.3 513.8 552.1 270.0 573.6 779.5 823.0 1002.2 465.7 278.1 243.3 416.3 893.1 248.9 419.2 590.6 284.6 1512.1 1123.5 430.3 632.0 1171.5 HTATSF1 TAT-SF1 ENSG00000102241 "HIV-1 Tat specific factor 1" O43719 X 136497079-136512346 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 173.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000504 Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA000504: AB_10752094" "unprognostic (3.56e-2)" "prognostic favorable (3.78e-4)" "unprognostic (1.72e-1)" "unprognostic (2.56e-2)" "unprognostic (6.72e-2)" "unprognostic (3.70e-1)" "unprognostic (3.32e-3)" "unprognostic (3.27e-1)" "unprognostic (2.09e-2)" "unprognostic (1.49e-1)" "unprognostic (1.73e-2)" "unprognostic (3.37e-2)" "prognostic favorable (8.13e-8)" "unprognostic (7.12e-2)" "unprognostic (2.67e-2)" "unprognostic (2.25e-2)" "unprognostic (4.05e-1)" 38.9 99.7 53.4 31.0 54.1 54.7 35.7 56.0 60.6 33.5 45.9 34.8 25.4 39.4 59.1 30.3 35.1 28.6 65.4 51.5 74.1 43.3 30.8 26.9 34.5 60.8 56.4 60.2 27.7 52.8 144.7 36.4 56.7 35.3 35.3 56.1 28.4 39.6 181.8 35.1 26.0 34.6 56.1 28.5 32.5 41.5 79.9 43.0 47.6 109.2 35.7 35.1 27.8 55.3 151.4 79.3 99.9 70.5 72.1 54.0 87.1 71.5 60.4 57.2 55.5 47.6 66.0 114.1 163.1 68.1 66.3 66.0 120.5 52.3 75.0 86.5 106.9 70.9 99.9 59.2 40.8 138.1 57.7 48.4 66.1 63.2 39.3 40.8 60.3 166.3 67.4 81.0 76.5 114.3 135.7 115.4 58.7 139.4 115.7 104.2 123.7 103.3 62.0 105.9 69.0 106.9 66.7 54.4 56.4 83.9 39.8 96.5 57.4 69.2 52.2 79.5 126.1 47.6 69.1 92.7 44.4 192.4 50.3 48.4 20.6 33.2 41.0 21.5 44.5 33.9 44.4 42.2 28.5 33.3 44.8 40.7 6.7 49.7 35.3 20.6 47.9 27.9 53.4 54.1 56.0 60.6 51.5 74.1 60.8 56.4 56.7 56.1 79.9 55.3 28.2 51.3 42.9 11.4 36.8 29.6 38.0 28.0 38.7 52.5 25.8 23.5 173.3 20.0 53.1 49.7 10.4 95.3 37.6 26.2 49.0 36.7 6.8 51.0 39.3 29.8 81.2 55.5 10.2 34.3 69.8 42.1 42.3 32.9 34.8 48.4 10.4 22.8 38.2 42.1 12.1 37.8 28.5 19.5 19.2 11.7 45.1 30.3 32.0 7.5 34.4 78.0 25.7 8.0 13.6 32.5 18.5 53.8 54.3 37.2 20.4 32.1 44.4 56.7 46.0 46.9 41.0 29.4 92.2 42.7 26.6 116.8 51.6 45.8 32.6 36.8 HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529725-74533332 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria NA NA 260000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "CAB004004: AB_326421, HPA006602: AB_2667622, HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" 11.4 8.6 8.1 8.1 8.7 11.1 6.8 9.1 9.7 7.1 7.7 6.4 6.9 6.9 1.0 6.0 7.1 4.7 9.4 8.1 8.3 8.1 6.5 6.6 7.8 8.6 8.5 10.9 7.4 9.4 4.7 6.3 8.3 4.8 3.3 2.5 8.5 5.3 14.5 5.4 7.9 5.3 8.2 9.9 6.4 6.2 9.6 9.1 6.8 9.0 4.8 6.5 5.8 9.2 19.1 14.7 14.7 12.6 21.3 9.0 30.1 17.0 10.3 10.3 7.0 21.1 8.5 16.6 12.9 10.7 26.0 19.7 12.0 19.6 2.4 34.0 31.4 33.3 10.8 19.0 19.8 15.3 22.4 9.9 13.7 18.4 19.5 18.4 14.2 23.5 43.9 24.9 9.7 14.1 22.0 31.1 10.0 22.8 37.7 15.8 37.0 17.1 9.6 8.2 15.1 17.7 8.9 18.6 32.5 7.3 9.3 13.2 10.6 19.2 19.7 33.4 35.3 29.5 10.2 9.8 13.6 23.4 13.0 5.8 7.0 4.0 4.8 5.7 5.8 11.0 4.8 4.1 8.6 9.9 4.3 4.1 2.6 5.0 4.5 4.5 5.7 5.5 8.1 8.7 9.1 9.7 8.1 8.3 8.6 8.5 8.3 8.2 9.6 9.2 30.7 0.0 4.8 6.2 27.3 20.6 19.7 33.8 13.6 12.0 17.4 21.7 0.9 21.5 15.7 11.0 0.0 24.7 25.8 12.5 35.2 32.4 30.8 11.9 18.1 29.6 9.0 118.5 6.3 17.7 37.8 23.3 11.2 12.9 27.3 20.9 22.9 12.7 31.5 10.1 6.3 12.3 20.3 10.7 19.4 48.9 24.8 14.6 30.2 2.8 26.3 20.2 30.9 5.5 7.5 26.1 16.8 20.7 36.0 21.3 24.8 36.8 13.5 16.3 26.3 18.7 56.5 64.3 43.3 16.7 22.0 20.2 20.6 27.1 20.0 15.7 HYPK "C15orf63, FLJ20431, HSPC136" ENSG00000242028 "Huntingtin interacting protein K" Q9NX55 15 43796142-43804427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055252 Uncertain Supported Nucleoplasm,Microtubules NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Microtubules "HPA055252: AB_2682759" "unprognostic (2.89e-2)" "unprognostic (5.82e-2)" "unprognostic (2.14e-2)" "unprognostic (7.58e-3)" "unprognostic (1.15e-1)" "unprognostic (1.08e-3)" "unprognostic (3.55e-1)" "unprognostic (1.48e-1)" "unprognostic (4.41e-2)" "unprognostic (1.04e-1)" "unprognostic (5.36e-3)" "unprognostic (2.39e-3)" "unprognostic (6.52e-7)" "unprognostic (2.05e-1)" "unprognostic (8.89e-2)" "unprognostic (2.61e-1)" "unprognostic (2.78e-4)" 8.9 9.8 13.8 5.9 13.8 4.9 6.5 16.6 22.0 5.0 13.8 5.0 3.7 4.3 5.1 4.2 6.0 2.9 8.5 13.8 15.0 6.5 14.2 7.6 6.5 14.7 15.2 6.2 9.4 6.2 5.6 3.6 14.7 6.8 3.8 8.6 5.5 4.3 19.2 6.1 5.1 4.9 13.4 5.5 5.8 7.9 14.2 6.1 5.2 14.7 7.7 8.3 4.3 15.4 13.5 36.8 17.3 19.5 11.6 11.5 6.5 21.8 13.1 18.9 12.6 23.7 7.4 19.8 25.9 16.7 17.8 23.1 30.3 24.9 14.3 17.3 37.3 26.4 64.6 34.0 17.8 30.4 16.3 10.1 24.2 21.3 18.1 9.3 14.7 20.9 40.5 16.9 17.2 33.5 19.2 33.9 19.5 48.6 40.9 15.4 12.6 22.4 17.7 26.5 33.9 24.7 20.7 31.1 13.3 10.6 23.7 19.5 13.3 22.6 11.8 24.2 55.8 20.5 40.6 46.2 15.1 33.1 26.8 16.8 25.7 22.1 25.0 37.7 26.4 30.0 26.8 26.7 23.5 31.4 29.9 27.9 9.4 26.7 47.7 39.8 27.5 23.5 13.8 13.8 16.6 22.0 13.8 15.0 14.7 15.2 14.7 13.4 14.2 15.4 11.3 6.4 14.5 0.0 11.1 30.0 15.0 8.1 13.6 11.2 14.4 11.9 0.7 8.6 12.1 7.3 54.2 6.6 8.2 6.4 9.8 6.5 2.4 7.2 9.6 10.7 10.7 9.5 0.0 8.4 4.4 12.5 26.0 7.7 8.8 4.5 6.4 6.5 3.9 13.5 0.0 11.6 8.2 4.4 26.2 1.1 5.0 9.1 23.2 0.0 4.7 4.9 6.2 0.0 0.0 6.8 4.7 2.2 11.3 14.8 7.2 10.4 15.4 28.5 0.0 23.2 11.8 3.9 4.7 19.4 37.4 4.9 10.4 9.1 9.4 11.1 IAH1 ENSG00000134330 "Isoamyl acetate hydrolyzing esterase 1 (putative)" Q2TAA2 2 9473658-9496543 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 433.4;Late spermatids: 503.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040523, HPA076040" Approved Approved Nucleoplasm NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA040523: AB_2677021, HPA076040: " "unprognostic (1.51e-2)" "unprognostic (1.19e-2)" "unprognostic (1.27e-1)" "unprognostic (9.41e-2)" "unprognostic (9.35e-2)" "unprognostic (2.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.28e-2)" "unprognostic (2.98e-2)" "unprognostic (5.40e-2)" "unprognostic (7.39e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (2.42e-2)" "unprognostic (3.91e-2)" 40.7 47.5 27.5 16.9 28.2 27.3 34.1 32.6 37.3 33.3 32.6 41.2 20.0 30.4 31.4 26.6 28.2 23.0 56.9 27.4 29.6 39.4 46.0 31.3 27.0 27.6 27.8 35.6 23.3 45.6 31.1 24.2 28.6 26.6 29.1 22.3 22.4 29.3 43.0 22.6 26.2 27.4 27.5 25.9 29.9 65.8 29.0 28.5 28.8 72.6 31.0 30.6 29.9 31.8 41.0 40.8 4.7 0.5 73.4 140.7 0.9 33.4 76.8 48.7 46.4 0.5 44.2 21.1 17.6 106.7 35.2 27.8 15.4 32.2 48.5 81.2 26.8 26.7 16.1 27.5 139.6 0.1 21.2 85.1 92.9 36.6 42.6 93.6 49.2 37.8 0.4 13.3 100.1 39.4 106.6 4.2 6.4 53.6 20.6 26.0 0.1 6.1 79.4 21.1 29.0 56.2 26.0 37.2 52.6 2.4 37.9 46.4 38.6 38.7 17.0 17.5 52.6 10.6 0.7 8.2 53.4 16.6 44.3 33.3 38.0 31.9 30.2 35.3 33.8 38.5 35.2 34.6 49.6 32.7 27.2 30.9 23.0 37.6 42.8 52.4 46.0 25.6 27.5 28.2 32.6 37.3 27.4 29.6 27.6 27.8 28.6 27.5 29.0 31.8 44.4 32.1 26.2 25.1 53.7 89.9 100.5 92.4 21.6 33.6 41.3 51.2 45.4 52.9 40.1 49.7 12.5 74.2 65.0 36.2 92.0 68.9 433.4 49.9 56.9 30.1 25.7 41.4 43.2 76.9 109.8 73.5 16.8 50.1 36.8 74.0 36.4 53.1 87.4 42.1 35.1 28.6 42.7 78.2 95.2 503.0 93.8 66.3 92.5 19.7 116.8 44.0 80.3 23.1 44.4 90.5 37.3 73.0 38.5 75.6 68.0 138.8 42.7 57.4 98.6 82.8 75.2 243.2 48.8 41.4 95.8 44.5 64.9 87.0 47.5 89.5 IBA57 "C1orf69, FLJ12734" ENSG00000181873 "Iron-sulfur cluster assembly factor IBA57" Q5T440 1 228165804-228182257 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Heme biosynthesis" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030555, HPA030556, HPA030557" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA030555: AB_2673522, HPA030556: AB_2673523, HPA030557: AB_10670433" "unprognostic (3.00e-2)" "unprognostic (1.71e-1)" "unprognostic (1.36e-1)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "unprognostic (8.16e-3)" "unprognostic (1.03e-1)" "unprognostic (6.11e-2)" "unprognostic (7.01e-2)" "unprognostic (8.00e-3)" "unprognostic (2.87e-2)" "unprognostic (1.61e-1)" "prognostic favorable (1.71e-9)" "unprognostic (4.94e-2)" "unprognostic (5.02e-1)" "unprognostic (5.04e-3)" "unprognostic (7.14e-2)" 2.0 2.7 2.6 1.4 2.3 4.1 1.4 2.9 2.5 1.3 2.2 1.8 1.6 1.8 0.5 1.6 1.3 1.0 3.3 2.1 2.0 2.0 2.8 1.9 1.6 2.7 2.2 1.9 2.9 2.1 0.9 1.4 2.3 1.2 1.4 0.5 1.7 1.0 6.1 3.0 1.7 1.7 2.1 1.7 2.0 1.1 2.8 1.3 1.3 4.0 1.7 1.3 1.2 3.5 2.5 2.5 2.7 1.2 1.3 1.4 3.3 1.5 0.7 1.1 0.6 5.3 2.1 5.3 3.1 1.6 0.6 4.4 2.0 3.2 1.0 1.1 4.5 3.1 3.5 2.6 1.1 3.7 3.5 2.2 1.8 1.3 1.5 1.0 1.6 3.2 5.4 2.4 1.1 2.0 3.6 2.2 2.0 3.4 2.8 4.4 3.1 2.4 1.6 5.1 4.1 2.8 2.4 7.5 1.9 0.5 6.0 4.9 3.8 3.0 2.8 2.1 3.7 1.8 0.9 2.6 1.4 1.6 2.3 1.6 0.4 0.2 0.6 0.4 1.0 0.4 0.5 0.5 0.3 0.7 0.7 0.7 0.5 0.8 0.4 1.0 0.5 0.2 2.6 2.3 2.9 2.5 2.1 2.0 2.7 2.2 2.3 2.1 2.8 3.5 5.7 9.6 11.0 4.2 10.2 8.2 8.8 3.9 2.8 5.8 5.6 5.6 15.3 8.6 9.2 0.0 12.5 10.7 5.0 14.5 7.9 5.4 22.2 5.2 6.0 8.8 7.2 49.3 3.8 6.9 8.6 5.2 5.1 10.3 15.2 6.7 5.3 7.9 5.5 3.3 4.1 8.0 4.1 4.4 6.4 30.7 3.7 6.0 7.2 6.5 4.2 4.4 4.1 3.0 5.8 8.8 6.3 7.2 5.8 6.3 9.4 6.7 3.2 19.5 6.6 9.7 4.7 14.9 11.2 4.4 6.0 16.3 7.2 8.3 11.9 8.3 IDH3G ENSG00000067829 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma" P51553 X 153785766-153794523 "Citric acid cycle related proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 284.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000425, HPA002017" Supported Approved Nucleoli,Mitochondria Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" "HPA000425: AB_1079097, HPA002017: AB_1079096" "unprognostic (4.24e-2)" "unprognostic (1.43e-3)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (6.57e-2)" "unprognostic (2.25e-1)" "unprognostic (4.35e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (1.59e-2)" "unprognostic (2.81e-2)" "unprognostic (1.96e-1)" "prognostic favorable (5.73e-6)" "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (2.91e-2)" "unprognostic (2.46e-1)" 52.0 67.1 45.5 38.5 50.0 60.3 49.9 47.8 61.3 44.1 46.5 57.2 52.3 50.7 23.5 50.2 44.8 35.0 91.9 54.9 48.8 68.5 49.2 42.0 40.3 50.5 45.7 49.3 48.3 45.5 47.9 28.3 52.3 43.8 34.6 24.4 51.7 39.9 100.5 51.7 54.7 34.5 43.9 51.8 52.2 32.1 49.1 35.2 48.0 82.9 34.9 44.3 43.2 47.2 94.9 90.0 47.3 65.9 74.4 59.4 62.0 47.3 64.1 80.5 84.3 76.0 66.5 121.4 80.2 74.7 68.2 67.2 72.6 69.2 30.0 38.9 101.7 43.0 118.9 59.0 85.5 61.6 87.5 76.1 48.0 64.4 69.4 50.4 65.3 50.3 24.7 60.4 64.7 138.5 72.0 76.0 21.6 84.2 118.0 62.7 43.3 105.8 94.4 61.1 59.5 42.8 30.2 96.3 48.0 20.8 39.6 51.9 56.0 49.9 34.1 76.8 112.5 89.0 22.6 152.1 81.8 75.8 57.6 178.1 159.3 165.8 71.8 163.9 68.0 68.5 73.2 71.2 163.1 78.9 57.9 63.7 57.8 86.5 169.6 101.3 107.5 140.1 45.5 50.0 47.8 61.3 54.9 48.8 50.5 45.7 52.3 43.9 49.1 47.2 44.4 35.3 33.8 5.5 49.2 80.9 67.5 103.9 37.5 34.9 48.4 57.9 55.1 50.1 55.0 51.5 29.2 99.8 48.2 145.0 207.4 93.4 132.0 42.2 39.4 44.6 62.3 41.4 5.6 90.5 98.7 48.2 47.9 39.8 93.8 43.6 43.2 35.4 131.0 18.5 6.4 107.0 79.3 98.0 77.0 284.2 53.4 75.6 67.6 3.7 116.4 50.8 64.9 3.0 5.0 73.5 133.8 58.6 49.7 35.6 222.4 253.1 50.7 49.3 52.6 47.4 68.2 15.9 18.3 50.3 77.4 110.8 55.2 103.0 112.7 64.2 IKZF4 "Eos, ZNFN1A4" ENSG00000123411 "IKAROS family zinc finger 4" Q9H2S9 12 56007659-56038435 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.9" "Lineage enriched" "Detected in single" 12 "T-cells: 1.9" "Cell line enhanced" "Detected in many" "HDLM-2: 36.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046270, HPA049016" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA046270: AB_2679607, HPA049016: AB_2680600" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (1.34e-1)" "unprognostic (8.95e-3)" "unprognostic (5.67e-2)" "unprognostic (2.08e-2)" "unprognostic (3.63e-3)" "prognostic favorable (3.46e-4)" "unprognostic (2.42e-1)" "unprognostic (5.43e-2)" "prognostic favorable (4.37e-4)" "unprognostic (6.52e-2)" "unprognostic (7.97e-2)" "unprognostic (3.64e-1)" "unprognostic (1.26e-1)" "unprognostic (9.98e-3)" "unprognostic (7.74e-3)" 4.9 9.2 5.6 2.1 5.7 3.8 3.7 7.1 6.5 4.8 5.7 5.5 1.6 4.5 4.0 2.6 5.8 2.7 4.1 5.3 5.8 3.7 3.2 3.7 2.1 6.4 6.2 7.6 2.9 8.1 7.5 3.0 5.8 3.9 2.0 8.5 2.7 4.2 9.9 2.5 3.5 2.9 5.5 2.9 4.1 5.0 6.2 4.0 5.1 5.4 2.3 4.3 3.2 6.0 1.7 1.6 11.6 3.9 2.3 2.4 2.7 1.8 3.1 2.1 3.0 6.5 2.5 1.1 2.0 2.9 2.3 1.3 1.5 1.8 4.6 36.2 1.7 7.3 1.7 3.0 2.6 3.3 2.6 4.0 2.1 2.2 1.7 3.9 2.2 0.2 10.7 5.5 3.4 2.0 4.1 1.6 5.1 1.8 1.4 3.6 3.1 1.3 3.1 1.4 4.4 3.8 2.6 0.8 4.3 2.9 3.0 3.3 1.3 1.8 3.1 1.8 1.5 3.5 2.2 1.5 3.7 3.2 2.4 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.9 0.1 5.6 5.7 7.1 6.5 5.3 5.8 6.4 6.2 5.8 5.5 6.2 6.0 5.5 3.2 9.4 10.7 2.5 3.6 1.9 3.4 10.2 20.3 16.6 15.4 7.5 10.0 4.2 3.7 8.4 3.0 0.8 3.9 1.9 2.9 13.8 7.7 10.4 5.3 6.0 4.2 13.3 4.2 2.8 8.8 2.0 8.0 1.3 4.0 8.2 6.7 2.7 8.4 17.7 3.0 4.1 9.8 3.1 2.7 8.7 4.1 5.4 7.5 6.0 18.3 0.0 14.6 15.5 4.3 2.1 10.9 1.6 2.4 1.7 4.9 4.3 12.3 0.0 10.3 9.9 21.2 5.9 10.4 3.3 4.0 3.8 16.0 2.3 2.1 IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038372, HPA058308" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038372: AB_10669643, HPA058308: AB_2732620" "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.17e-2)" "unprognostic (9.67e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (7.59e-2)" "unprognostic (4.66e-3)" "unprognostic (5.15e-3)" "prognostic favorable (6.72e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (4.66e-1)" "unprognostic (4.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-3)" 11.7 15.6 42.8 6.4 43.7 11.1 19.3 45.5 66.4 13.5 41.8 12.7 8.6 11.5 29.8 11.7 10.4 5.1 26.2 42.8 42.3 27.2 18.6 8.9 9.5 42.4 42.0 17.5 16.4 17.9 23.3 6.9 42.3 14.3 10.0 37.7 11.8 14.1 50.0 12.5 9.5 10.7 42.9 10.8 15.1 16.7 43.0 24.8 13.2 42.1 13.1 10.9 12.6 43.5 22.9 26.9 95.6 21.0 14.9 9.9 15.3 19.9 8.7 16.2 11.7 21.0 17.5 20.7 18.7 15.9 32.5 25.8 37.6 28.8 23.8 24.9 52.6 29.4 45.5 32.3 15.8 29.6 19.9 8.0 27.1 8.7 19.2 29.5 17.5 48.8 38.0 23.2 15.9 28.2 48.5 48.9 15.8 114.6 26.3 41.1 72.2 20.6 54.6 26.2 22.5 27.0 32.5 11.6 32.5 61.9 37.1 35.1 2.6 15.3 27.2 16.2 42.2 17.2 58.2 47.5 24.9 24.9 18.5 21.9 3.0 32.2 28.9 3.4 26.3 34.1 25.3 29.5 8.1 32.1 32.0 39.8 0.8 37.3 3.0 40.2 35.4 13.6 42.8 43.7 45.5 66.4 42.8 42.3 42.4 42.0 42.3 42.9 43.0 43.5 29.2 35.3 14.6 30.7 22.4 18.2 26.8 60.5 12.0 30.6 44.6 55.1 56.8 18.6 26.8 60.7 33.3 36.3 17.6 21.7 119.3 17.0 39.8 30.2 16.9 19.4 56.5 47.4 40.6 24.5 32.5 19.7 20.9 33.8 22.7 22.7 18.2 45.0 21.3 43.7 48.0 30.6 52.9 7.7 11.4 10.5 13.4 9.4 8.8 24.4 10.3 85.3 30.9 51.3 60.7 15.8 26.7 20.7 22.0 26.0 18.6 98.4 28.9 38.5 32.9 19.1 51.0 61.6 23.0 19.6 27.3 23.7 24.2 16.2 34.7 26.2 ISCA1 "HBLD2, hIscA, ISA1, MGC4276" ENSG00000135070 "Iron-sulfur cluster assembly 1" Q9BUE6 9 86264546-86283102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 994.9;Erythroid cells: 315.5;Late spermatids: 804.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA042789 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "HPA042789: AB_10797022" "unprognostic (1.14e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-3)" "unprognostic (6.91e-2)" "unprognostic (2.08e-1)" "unprognostic (1.00e-3)" "unprognostic (2.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (2.66e-1)" "prognostic favorable (3.83e-4)" "unprognostic (4.06e-1)" "unprognostic (1.24e-1)" "unprognostic (1.09e-2)" "unprognostic (3.31e-1)" 38.3 48.0 45.6 16.6 47.4 75.6 33.6 50.6 52.1 25.1 45.1 29.8 28.6 29.3 23.4 19.9 29.1 25.8 62.3 47.2 49.5 60.1 45.9 22.4 17.3 46.9 48.4 34.7 27.8 54.8 32.8 35.5 49.4 26.5 26.1 43.3 21.3 31.5 91.7 20.6 24.7 28.5 44.5 19.5 24.9 46.0 47.6 22.1 39.3 105.7 15.7 27.1 19.1 45.7 43.2 30.5 43.6 59.5 83.7 36.9 53.8 45.3 31.9 44.9 26.0 23.7 23.5 28.9 30.5 37.1 33.7 38.2 42.7 35.0 32.5 66.3 29.5 48.2 34.0 44.1 39.4 42.9 25.0 41.7 54.9 30.1 28.8 38.3 36.0 42.4 25.3 54.2 38.9 43.7 48.6 23.5 85.4 62.5 64.4 32.3 57.9 39.6 63.8 41.4 62.7 46.0 39.1 63.0 54.4 41.4 21.5 24.6 29.3 25.7 31.0 45.1 59.7 41.8 87.3 20.5 51.4 29.5 32.1 45.8 14.8 29.5 19.5 12.7 23.1 18.0 23.1 20.2 10.6 14.8 25.1 24.3 24.3 19.7 13.9 17.5 28.8 21.7 45.6 47.4 50.6 52.1 47.2 49.5 46.9 48.4 49.4 44.5 47.6 45.7 61.3 28.9 15.0 14.7 71.2 60.9 78.0 41.2 38.7 52.9 51.7 57.1 44.0 55.8 19.0 29.5 20.9 75.4 107.0 41.7 140.8 67.0 994.9 93.0 40.1 43.6 53.8 315.5 29.0 43.8 90.0 48.8 31.1 54.2 16.5 45.5 44.3 88.3 45.7 67.3 28.1 36.4 46.8 34.7 42.0 804.2 56.5 56.6 55.2 10.3 37.0 58.6 34.0 18.6 22.7 62.2 38.0 48.9 62.7 81.7 64.1 121.4 44.4 49.4 32.9 47.2 56.9 84.3 65.6 41.1 52.6 114.0 85.0 75.9 41.2 56.9 ISCA2 "HBLD1, ISA2" ENSG00000165898 "Iron-sulfur cluster assembly 2" Q86U28 14 74493756-74497106 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030492 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA030492: AB_10603772" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "unprognostic (5.73e-2)" "unprognostic (5.62e-2)" "unprognostic (2.51e-1)" "unprognostic (5.89e-3)" "unprognostic (6.03e-3)" "unprognostic (7.98e-2)" "unprognostic (1.66e-1)" "unprognostic (2.59e-2)" "unprognostic (1.31e-2)" "unprognostic (2.21e-1)" "prognostic favorable (1.68e-7)" "unprognostic (3.98e-2)" "unprognostic (1.47e-1)" "prognostic favorable (8.98e-5)" "unprognostic (5.23e-2)" 15.1 33.9 20.3 9.7 20.6 15.5 16.9 22.4 23.9 13.7 27.4 16.9 14.2 11.0 46.4 15.4 19.5 7.6 34.3 19.5 21.2 30.6 22.0 12.9 17.0 21.2 21.1 18.1 18.1 12.9 23.4 12.8 21.3 18.5 17.5 19.1 17.8 12.1 38.3 13.3 16.0 8.4 21.1 20.0 18.1 20.6 22.6 18.5 26.0 29.2 17.4 13.7 13.4 21.5 43.4 30.7 28.4 18.1 25.5 37.2 35.9 19.7 26.3 30.2 36.3 36.3 39.3 21.8 25.3 16.6 38.2 30.7 27.8 25.9 40.7 30.7 20.2 13.7 13.1 39.6 38.3 17.7 30.2 31.2 29.0 18.2 20.6 28.0 30.8 44.4 18.2 25.5 32.7 51.0 42.9 34.5 21.0 60.2 28.3 29.8 31.9 21.8 42.6 34.1 19.1 19.6 20.8 24.4 31.8 30.5 60.2 20.9 16.9 17.1 39.5 25.3 17.7 43.3 60.3 40.2 28.0 20.6 25.4 130.8 109.1 159.0 91.8 108.0 93.5 172.3 127.6 111.6 111.0 165.4 148.5 122.1 87.5 101.5 106.6 218.1 157.4 161.3 20.3 20.6 22.4 23.9 19.5 21.2 21.2 21.1 21.3 21.1 22.6 21.5 25.2 19.2 20.4 7.2 36.2 15.4 27.2 74.9 13.6 22.1 36.2 38.2 113.3 22.8 42.7 33.1 12.5 70.8 28.8 45.5 146.8 62.0 41.0 38.3 17.6 27.2 29.3 73.2 4.4 55.0 70.1 28.8 24.5 18.1 12.6 31.8 28.9 42.4 81.5 28.6 5.5 36.3 63.1 33.2 18.3 19.3 33.5 30.4 8.8 2.8 49.0 69.8 41.2 3.0 7.2 59.5 50.8 18.0 25.0 40.2 51.4 133.5 78.6 31.6 13.1 15.1 25.1 107.2 63.7 25.4 13.2 25.4 30.7 43.1 42.3 27.6 ISCU "hnifU, ISU2, NIFUN" ENSG00000136003 "Iron-sulfur cluster assembly enzyme" Q9H1K1 12 108562582-108569368 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1430.2;Late spermatids: 969.5;Proximal tubular cells: 1315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006329, HPA038602, HPA057592" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB006329: AB_425907, HPA038602: AB_2676109, HPA057592: AB_2683478" "unprognostic (1.72e-1)" "prognostic favorable (4.90e-7)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (2.43e-1)" "unprognostic (3.15e-2)" "unprognostic (1.33e-1)" "unprognostic (6.69e-3)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-3)" "unprognostic (2.49e-2)" "prognostic favorable (2.73e-7)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-3)" "prognostic favorable (6.12e-4)" 174.8 387.6 186.3 89.8 187.5 98.2 166.8 209.9 216.8 174.4 222.2 222.9 88.8 170.2 148.8 91.2 142.5 106.5 507.1 186.2 223.0 341.3 119.9 138.3 138.9 223.4 192.5 169.2 106.2 286.0 228.9 111.1 214.4 150.5 112.0 58.9 123.7 196.1 422.3 111.6 142.7 122.2 187.0 163.9 169.2 123.2 188.0 151.6 184.4 381.5 138.3 179.0 133.4 177.0 47.5 113.8 78.9 47.3 277.4 211.6 191.7 92.8 152.2 69.7 65.7 84.9 66.0 47.4 77.9 128.5 74.6 67.5 76.2 106.8 62.5 147.2 82.0 51.8 60.7 190.6 161.5 124.4 59.0 206.6 234.3 75.4 149.3 176.8 107.7 100.7 98.3 148.8 147.8 102.9 98.1 225.4 76.4 70.9 165.7 64.0 52.5 205.3 204.5 134.6 67.4 62.4 67.5 39.7 108.7 98.3 102.2 99.4 92.3 70.3 59.0 56.8 47.8 175.9 207.8 146.3 109.5 91.8 72.4 478.2 182.1 567.9 224.5 200.5 269.2 564.4 292.6 292.7 128.4 516.7 366.2 305.0 554.2 207.5 239.3 225.2 334.2 400.8 186.3 187.5 209.9 216.8 186.2 223.0 223.4 192.5 214.4 187.0 188.0 177.0 129.8 76.9 158.9 19.9 206.3 98.1 148.6 227.0 98.4 46.2 137.5 212.3 674.1 145.8 148.6 233.6 10.4 453.7 142.2 120.1 1430.2 154.3 433.2 78.1 76.5 140.8 75.0 165.5 52.6 149.8 164.0 165.5 64.2 37.1 116.5 89.1 126.0 112.3 263.0 45.4 53.7 117.6 193.3 140.1 110.2 969.5 202.0 129.9 249.1 23.4 502.4 167.9 163.7 14.6 26.0 141.3 96.3 308.4 299.4 171.8 235.9 1315.1 160.4 45.8 223.5 97.4 158.1 294.5 242.1 92.6 93.1 475.2 153.6 154.2 139.8 177.7 IWS1 "DKFZp761G0123, FLJ10006, FLJ14655, FLJ32319" ENSG00000163166 "Interacts with SUPT6H, CTD assembly factor 1" Q96ST2 2 127436207-127526886 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035719, HPA061866" Supported Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA035719: AB_10669527, HPA061866: AB_2684628" "unprognostic (3.11e-2)" "unprognostic (1.31e-1)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (8.49e-2)" "unprognostic (1.05e-1)" "unprognostic (4.27e-2)" "unprognostic (2.25e-1)" "unprognostic (4.32e-2)" "unprognostic (9.96e-2)" "unprognostic (1.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.10e-2)" "unprognostic (9.01e-2)" "unprognostic (9.81e-2)" 24.2 18.5 26.7 23.2 32.3 31.5 22.2 30.3 37.8 23.1 30.1 24.8 23.4 22.9 23.8 22.9 21.3 18.9 48.4 26.8 32.2 30.1 40.2 22.5 28.8 30.7 32.1 18.0 21.6 23.8 24.8 26.5 32.0 23.3 23.8 26.5 22.7 19.3 76.0 21.6 24.4 21.9 27.7 27.6 23.1 23.2 31.5 31.2 20.7 62.0 28.4 25.8 23.4 40.4 52.0 34.5 68.4 45.0 51.0 42.4 71.4 73.9 50.0 67.2 55.9 81.6 38.8 48.7 38.2 59.3 51.4 41.9 66.7 58.2 79.4 50.7 45.4 68.1 50.6 92.9 60.2 78.2 54.5 42.0 43.6 71.5 64.0 35.7 58.0 60.3 72.8 37.0 64.3 48.3 77.7 63.4 92.2 43.0 46.8 68.9 53.5 44.9 67.6 62.0 53.4 34.7 52.9 65.9 60.3 73.4 29.6 53.5 66.4 66.3 50.4 40.4 43.8 28.6 33.6 64.5 36.6 54.2 45.0 3.6 13.2 18.5 9.7 14.8 11.8 11.4 11.1 11.8 13.0 15.1 10.5 11.0 13.9 15.0 17.3 11.8 11.0 9.5 26.7 32.3 30.3 37.8 26.8 32.2 30.7 32.1 32.0 27.7 31.5 40.4 23.1 112.2 74.3 35.3 36.6 15.7 55.3 22.8 23.9 27.9 16.9 15.7 77.4 21.5 53.5 16.5 27.1 40.0 33.5 35.1 19.6 38.6 13.2 38.5 39.8 28.9 28.1 30.7 21.9 25.5 56.3 41.9 32.1 36.8 42.3 42.3 20.7 25.7 27.1 21.9 27.8 25.7 30.5 16.4 25.4 8.5 39.1 29.2 10.6 25.3 40.1 26.4 46.4 25.6 105.0 41.9 28.0 31.6 37.5 53.8 25.1 19.1 44.6 44.7 32.9 29.3 35.6 69.8 52.0 24.1 17.0 92.8 37.4 34.6 26.9 77.2 KIAA0232 ENSG00000170871 KIAA0232 Q92628 4 6781375-6884170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 10.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036891, HPA036892, HPA061498" Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA036891: AB_10672272, HPA036892: AB_2675366, HPA061498: AB_2684541" "unprognostic (6.88e-3)" "unprognostic (2.74e-1)" "unprognostic (8.98e-2)" "unprognostic (4.87e-2)" "unprognostic (2.43e-1)" "unprognostic (4.13e-2)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (1.85e-1)" "unprognostic (3.16e-1)" "unprognostic (1.32e-2)" "unprognostic (2.78e-1)" "prognostic favorable (3.91e-10)" "unprognostic (1.21e-1)" "unprognostic (8.57e-2)" "unprognostic (2.04e-1)" "unprognostic (3.18e-2)" 13.0 12.0 18.6 8.5 19.9 16.2 13.3 20.2 20.9 12.0 17.8 14.0 8.5 15.4 12.6 20.6 15.3 12.4 33.2 18.0 22.3 18.8 15.0 12.0 7.5 18.2 22.5 13.1 10.6 23.9 10.3 10.4 19.8 14.7 12.3 24.7 8.9 14.6 32.5 7.6 11.5 13.1 20.1 12.9 10.9 12.0 23.4 11.7 15.1 51.1 8.6 10.4 9.8 21.0 13.7 13.0 26.7 16.7 18.8 20.2 14.0 17.4 18.1 12.0 10.1 8.2 11.3 9.0 5.8 19.7 18.5 7.0 13.7 7.7 15.5 5.1 5.6 26.7 11.1 11.0 9.9 11.6 33.6 13.6 17.7 13.4 7.4 15.4 12.6 8.9 20.3 7.6 15.4 6.7 22.3 11.7 14.1 10.2 14.3 15.7 27.3 4.2 20.3 12.8 20.2 13.1 12.9 11.4 12.1 18.3 14.5 21.1 16.0 11.0 12.8 9.8 15.2 13.1 14.1 7.0 13.5 12.2 30.3 2.0 2.0 5.7 2.1 1.4 2.9 1.3 1.6 2.5 1.3 1.3 1.5 1.6 10.6 1.8 2.1 2.0 1.6 0.9 18.6 19.9 20.2 20.9 18.0 22.3 18.2 22.5 19.8 20.1 23.4 21.0 27.6 32.1 39.2 62.3 19.1 12.7 27.4 12.9 24.5 77.2 29.0 20.6 132.1 10.0 29.0 12.9 37.5 14.7 23.6 47.9 41.1 23.4 45.0 74.4 28.0 20.6 25.1 49.9 123.8 11.7 7.7 27.7 44.9 38.7 12.6 16.3 15.0 42.9 11.2 99.3 120.7 20.9 30.5 23.9 11.8 64.2 24.8 28.4 7.2 73.1 34.8 49.7 27.8 90.0 138.0 21.8 24.8 33.1 24.2 28.0 29.6 24.6 58.0 44.6 26.3 39.4 31.6 31.6 22.4 19.2 11.1 22.4 27.4 27.0 17.5 35.7 KIAA0319L "AAVR, KIAA1837" ENSG00000142687 "KIAA0319 like" Q8IZA0 1 35433492-35557950 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 47.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072692 Supported Supported "Nucleoli,Golgi apparatus" NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoli "HPA072692: AB_2686549" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (4.23e-3)" "unprognostic (1.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.92e-5)" "unprognostic (3.41e-3)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.79e-1)" "prognostic favorable (1.27e-4)" "unprognostic (1.47e-1)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (1.84e-1)" 14.3 26.6 28.3 13.0 28.0 15.9 27.8 23.4 28.0 25.6 28.9 25.6 26.3 14.4 26.2 18.3 35.1 21.3 44.5 28.0 27.6 38.2 34.2 30.9 17.7 26.9 29.2 14.9 42.1 45.6 26.9 30.6 25.5 34.9 30.0 34.1 33.5 18.5 37.7 20.1 24.8 14.4 24.8 20.1 34.4 17.1 32.4 17.8 41.4 40.1 16.8 15.8 15.1 24.9 13.5 19.6 39.8 31.5 52.7 36.9 37.8 17.9 37.8 25.5 37.5 21.2 52.9 15.0 48.0 19.6 38.1 26.1 29.7 28.8 28.9 23.8 21.7 20.3 23.4 23.6 41.3 16.9 26.8 52.3 36.2 29.5 38.0 84.3 42.2 18.1 27.2 21.0 35.2 13.6 10.1 14.3 45.3 37.4 11.7 11.3 33.8 18.7 41.8 32.4 8.7 24.6 25.8 30.6 53.3 86.9 32.3 23.1 43.6 17.4 18.7 14.9 28.0 31.1 26.7 9.8 44.3 21.8 17.7 8.8 19.4 9.4 5.0 6.1 4.8 3.4 4.1 4.7 5.6 4.1 5.5 4.0 47.2 9.8 4.0 3.7 4.0 8.7 28.3 28.0 23.4 28.0 28.0 27.6 26.9 29.2 25.5 24.8 32.4 24.9 24.2 73.7 74.1 85.2 18.3 7.9 14.4 16.5 15.4 74.8 33.9 26.0 55.0 47.1 42.4 35.0 108.4 33.3 16.6 35.4 3.9 19.2 9.6 21.0 17.7 24.6 21.6 14.7 93.2 32.5 22.5 19.4 28.5 30.8 21.5 42.7 28.9 47.4 19.1 63.9 95.2 59.5 16.2 31.4 7.6 7.5 17.4 19.2 14.2 62.8 31.4 30.5 29.9 115.1 99.3 30.3 27.6 17.3 17.2 26.0 36.8 17.5 45.4 61.9 6.6 24.5 15.7 22.5 21.2 17.8 9.2 31.2 21.9 30.1 31.2 14.8 KIFBP "DKFZP586B0923, KBP, KIAA1279, KIF1BP, TTC20" ENSG00000198954 "Kinesin family binding protein" Q96EK5 10 68988803-69043544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 9.5;Cardiomyocytes: 40.7;Cytotrophoblasts: 21.7;Extravillous trophoblasts: 19.5;Fibroblasts: 8.7;Hofbauer cells: 16.7;Syncytiotrophoblasts: 8.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035538, HPA035539" Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "HPA035538: AB_10601130, HPA035539: AB_2674676" "unprognostic (4.28e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (4.19e-1)" "unprognostic (1.96e-1)" "unprognostic (2.13e-3)" "unprognostic (4.23e-3)" "unprognostic (3.72e-2)" "unprognostic (3.52e-2)" "unprognostic (7.74e-2)" "unprognostic (6.23e-3)" "unprognostic (8.74e-2)" "prognostic favorable (2.60e-4)" "unprognostic (5.19e-2)" "unprognostic (9.45e-2)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" 19.9 22.1 21.3 6.7 24.4 1.3 11.2 24.4 32.5 14.0 19.7 11.9 6.4 12.5 15.9 12.2 11.8 12.6 37.3 24.6 23.8 19.5 13.8 9.9 6.7 23.9 22.2 12.3 8.5 33.8 13.6 14.8 24.5 16.6 10.3 25.7 9.8 17.3 30.4 8.7 8.1 15.3 25.7 7.5 11.4 16.2 22.7 7.6 19.2 43.3 9.2 15.2 9.3 28.1 49.1 36.9 33.3 36.1 48.3 42.5 0.2 63.2 58.0 63.4 71.9 40.4 24.7 0.1 20.7 57.3 39.5 40.2 57.0 37.9 63.6 27.5 48.8 9.5 22.0 24.0 32.4 13.3 11.5 26.4 30.4 42.3 37.7 60.5 46.6 15.1 13.1 14.0 78.4 23.3 13.0 15.8 20.7 25.4 84.1 15.5 27.7 7.2 67.4 12.4 25.0 18.1 36.0 48.9 34.8 32.2 60.3 10.2 46.3 28.0 25.7 24.6 64.0 2.8 0.3 9.0 35.9 19.8 15.7 1.8 4.3 2.4 7.3 7.5 8.8 5.1 8.4 7.2 5.5 4.1 9.6 7.8 1.6 6.9 12.9 2.8 8.0 5.0 21.3 24.4 24.4 32.5 24.6 23.8 23.9 22.2 24.5 25.7 22.7 28.1 9.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.7 0.0 0.0 0.0 0.0 21.7 3.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 19.5 8.7 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 8.3 0.9 0.0 0.0 0.0 KLF15 KKLF ENSG00000163884 "Kruppel like factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cardiomyocytes: 29.7;Distal tubular cells: 29.4;Hepatocytes: 66.9;Peritubular cells: 19.9;Proximal tubular cells: 22.1" "Cancer enhanced" "Detected in many" "liver cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 57.4;HHSteC: 34.8;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: AB_10600819" "unprognostic (3.77e-3)" "unprognostic (1.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-3)" "unprognostic (2.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-2)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "prognostic favorable (3.27e-7)" "unprognostic (6.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.91e-2)" "unprognostic (5.58e-3)" 36.5 6.2 42.2 0.8 50.7 0.1 25.4 45.1 69.5 15.8 37.5 18.6 1.2 19.1 4.1 7.1 29.7 3.5 31.4 41.7 40.6 20.3 92.5 18.6 1.8 64.9 45.9 46.3 48.5 4.5 10.4 1.7 47.2 17.6 0.9 3.9 19.7 5.2 67.3 10.3 10.2 2.5 44.9 3.6 30.2 5.6 44.7 1.2 11.1 32.4 0.8 27.0 12.0 48.4 0.8 0.0 2.2 9.2 57.4 1.0 10.0 0.6 1.4 0.7 1.3 1.1 0.0 3.4 0.9 0.0 1.7 0.1 5.3 0.1 0.2 0.2 2.0 0.1 0.8 7.9 34.8 0.0 0.2 5.4 0.5 0.0 1.2 0.0 0.6 4.5 4.3 7.4 0.2 0.7 0.0 1.3 6.6 1.3 0.3 4.7 0.2 20.2 0.1 0.8 0.7 7.7 0.1 0.3 10.2 3.3 0.5 4.6 0.3 0.3 0.4 0.3 0.3 4.7 0.6 0.7 0.2 1.5 1.3 25.1 7.6 10.3 7.0 10.2 8.2 12.3 7.3 7.4 8.2 11.4 9.4 11.3 16.7 12.8 9.3 9.0 10.5 11.7 42.2 50.7 45.1 69.5 41.7 40.6 64.9 45.9 47.2 44.9 44.7 48.4 1.5 6.4 4.6 22.9 0.8 0.0 2.9 0.2 0.6 1.3 7.8 1.8 29.7 15.7 0.7 0.0 0.0 0.1 0.1 0.0 29.4 0.1 0.1 2.5 4.4 2.1 0.0 2.7 0.6 0.0 0.2 8.1 3.1 3.4 0.0 13.7 8.2 66.9 0.1 0.0 2.8 0.1 0.0 2.6 0.0 0.8 12.2 0.4 1.8 2.8 0.0 12.0 0.0 15.1 5.7 0.4 0.0 19.9 0.9 5.2 0.0 22.1 0.8 3.3 0.0 12.0 5.5 0.1 0.1 0.3 0.0 0.3 0.5 0.6 0.1 1.8 KYAT1 "CCBL1, GTK, KATI" ENSG00000171097 "Kynurenine aminotransferase 1" Q16773 9 128832942-128882494 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "Granulosa cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA021176, HPA021177, HPA027736" Approved Supported Cytosol NA NA 22000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA021176: AB_1846120, HPA021177: AB_1846119, HPA027736: AB_10611818" "unprognostic (6.51e-2)" "unprognostic (8.67e-3)" "unprognostic (1.05e-2)" "unprognostic (5.98e-3)" "unprognostic (2.15e-2)" "unprognostic (5.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-2)" "unprognostic (2.47e-1)" "unprognostic (8.60e-3)" "unprognostic (1.43e-1)" "unprognostic (3.65e-2)" "unprognostic (3.10e-2)" "unprognostic (5.79e-2)" "unprognostic (2.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" 3.5 4.7 12.3 3.6 13.3 2.3 4.0 13.0 15.5 7.2 10.6 4.7 2.5 5.8 2.9 5.3 6.4 2.7 10.3 12.1 11.8 7.8 12.7 3.6 5.0 13.2 12.3 6.2 3.1 5.5 8.7 2.5 12.8 7.4 1.3 7.5 4.2 4.3 12.6 7.7 4.2 3.1 12.3 5.4 4.9 5.6 12.9 8.9 6.1 8.7 4.8 7.2 6.7 18.0 4.8 9.8 9.3 10.6 6.9 11.4 3.0 5.5 8.0 6.2 8.0 3.9 9.7 8.3 2.9 4.6 7.0 14.9 13.9 11.1 9.3 10.0 7.3 5.7 27.7 9.6 7.7 5.0 1.9 4.5 7.1 7.1 7.7 21.8 11.3 22.7 8.2 9.0 8.5 3.1 14.0 3.4 15.2 18.3 7.6 16.4 6.4 18.9 8.7 1.7 10.5 7.4 9.9 2.9 6.2 12.8 6.6 1.6 7.0 4.6 7.9 7.1 5.0 15.2 11.0 11.6 9.6 8.3 3.2 0.1 1.4 2.9 5.1 1.8 4.5 7.7 5.7 6.0 5.5 3.3 5.9 6.7 0.9 3.3 2.9 2.4 7.0 3.3 12.3 13.3 13.0 15.5 12.1 11.8 13.2 12.3 12.8 12.3 12.9 18.0 2.6 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.0 0.6 0.0 0.0 5.0 0.9 0.0 3.9 1.6 0.0 2.6 3.3 0.7 0.0 0.0 0.0 0.2 2.4 0.7 0.0 4.2 0.0 45.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 7.3 2.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.1 1.3 1.3 0.0 0.0 LAMTOR5 "HBXIP, MGC71071, XIP" ENSG00000134248 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5" O43504 1 110401249-110407942 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1113.2;Proximal tubular cells: 2532.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006812 Approved Supported Cytosol NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA006812: AB_1079040" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (2.29e-1)" "unprognostic (3.54e-3)" "unprognostic (2.75e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.97e-2)" "unprognostic (7.58e-2)" "prognostic favorable (7.23e-4)" "unprognostic (2.80e-1)" "unprognostic (2.93e-1)" "unprognostic (1.65e-2)" "unprognostic (3.77e-2)" "unprognostic (3.80e-3)" "prognostic favorable (5.52e-4)" "unprognostic (6.66e-2)" 143.6 134.9 152.2 79.5 156.3 250.3 127.7 167.7 179.0 107.7 168.0 108.3 85.7 86.2 162.6 121.0 93.2 101.9 269.7 150.9 163.6 433.9 150.2 115.2 114.1 159.6 155.4 121.0 95.3 192.3 141.2 120.7 157.9 109.4 110.9 140.0 100.1 77.6 260.3 98.7 102.2 81.5 165.1 126.0 127.8 88.6 161.4 102.2 107.8 277.3 122.6 124.2 109.4 168.1 272.1 223.2 197.3 118.5 325.3 245.3 196.1 224.4 176.5 186.8 176.6 196.0 130.0 214.5 233.0 220.9 228.4 107.5 203.4 189.2 229.8 231.4 227.9 157.7 257.1 402.1 247.1 227.7 188.0 216.3 287.3 193.9 122.6 236.2 227.7 156.9 189.3 196.0 275.8 443.0 208.7 274.7 140.1 151.8 366.9 141.9 355.1 164.2 439.0 302.0 145.4 189.6 198.8 287.7 516.4 169.5 111.0 317.3 217.8 140.5 182.9 355.7 214.4 204.5 250.7 277.2 459.1 225.6 329.6 295.4 223.1 485.8 125.9 229.5 112.1 345.3 146.6 137.6 187.9 322.3 127.1 134.4 347.7 149.2 225.0 321.5 181.1 250.6 152.2 156.3 167.7 179.0 150.9 163.6 159.6 155.4 157.9 165.1 161.4 168.1 131.2 160.3 174.4 16.3 208.2 307.8 284.1 661.5 101.3 111.0 186.0 197.9 597.6 211.6 371.9 445.1 25.0 424.5 141.5 225.1 1113.2 389.2 67.5 215.8 141.8 193.1 222.3 158.9 15.4 331.0 370.7 194.0 99.9 191.1 146.4 97.0 133.9 311.9 424.8 89.2 17.6 302.6 449.6 154.4 189.2 112.8 264.7 175.3 350.4 18.7 320.9 297.9 137.0 9.5 23.3 403.9 296.4 239.2 100.6 360.9 315.4 2532.5 340.9 150.5 170.9 168.2 185.2 297.9 361.3 121.3 322.5 500.5 125.7 163.2 252.0 441.8 LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.5;Alveolar cells type 2: 8.2;Ductal cells: 7.1;Endometrial stromal cells: 10.5;Exocrine glandular cells: 7.9;Glandular and luminal cells: 8.6;Hofbauer cells: 6.0;Pancreatic endocrine cells: 6.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.3;basal ganglia: 23.4;cerebral cortex: 33.2;hippocampal formation: 45.4;white matter: 16.4" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.79e-1)" "unprognostic (1.74e-3)" "unprognostic (1.63e-1)" "unprognostic (1.48e-2)" "unprognostic (4.90e-2)" "unprognostic (1.39e-2)" "unprognostic (5.21e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-3)" 11.9 10.1 18.3 5.9 23.4 0.4 9.1 3.4 33.2 15.3 19.7 27.8 9.2 22.4 8.1 6.7 13.5 9.0 58.4 45.4 2.2 8.4 8.1 6.5 5.1 1.0 2.9 20.8 8.3 6.0 7.4 4.1 4.7 15.2 8.7 13.2 5.9 24.8 49.5 8.5 11.4 15.7 0.0 5.8 16.7 7.6 6.3 2.0 5.3 27.5 5.0 21.6 11.5 16.4 4.1 12.3 19.5 8.4 3.2 0.6 7.4 14.1 7.1 2.7 0.0 2.6 0.4 19.5 2.4 14.0 4.6 1.6 11.6 0.0 0.1 0.3 9.8 0.0 0.0 13.1 4.1 0.1 2.0 1.8 0.9 0.2 0.0 0.0 0.1 0.2 0.2 2.7 3.2 16.5 0.1 9.5 7.7 16.3 0.4 10.6 20.2 3.5 2.5 18.1 7.0 2.4 8.4 11.4 13.6 13.7 16.4 0.6 0.1 8.8 13.8 5.2 3.7 21.3 23.4 0.4 16.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 18.3 23.4 3.4 33.2 45.4 2.2 1.0 2.9 4.7 0.0 6.3 16.4 8.5 0.0 8.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 4.2 4.2 0.0 0.0 2.5 1.8 0.0 0.3 0.9 0.0 0.0 7.1 0.0 5.7 10.5 1.9 0.0 0.0 0.0 7.9 0.7 2.9 0.0 8.6 1.3 3.9 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.4 0.0 0.0 2.0 1.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.3 0.8 1.2 0.0 0.0 LDHB ENSG00000111716 "Lactate dehydrogenase B" P07195 12 21635342-21757857 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1947.7;kidney: 1726.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2502.3;Cytotrophoblasts: 1693.0;Distal tubular cells: 3306.5;Proximal tubular cells: 3483.9;Syncytiotrophoblasts: 1639.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 6021.8" "CAB004641, HPA019007" Enhanced Supported Cytosol No No 560000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB004641: AB_425525, HPA019007: AB_2670008" "unprognostic (2.93e-1)" "unprognostic (9.20e-3)" "unprognostic (6.10e-2)" "unprognostic (1.11e-1)" "unprognostic (5.39e-3)" "unprognostic (1.36e-3)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (5.34e-2)" "unprognostic (8.40e-2)" "unprognostic (2.91e-1)" "unprognostic (6.41e-2)" "prognostic favorable (2.51e-4)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (2.55e-1)" "unprognostic (9.32e-2)" 549.9 424.8 509.1 259.2 528.2 352.8 321.1 593.7 617.0 238.6 549.8 320.2 84.4 273.1 169.0 166.6 252.9 232.9 1947.7 484.1 581.9 1726.6 70.5 220.4 425.8 564.4 575.4 472.4 370.3 447.3 161.3 298.2 556.2 240.9 277.0 290.0 162.3 287.2 309.4 81.4 171.3 309.7 537.8 182.0 459.1 119.5 582.5 534.5 348.5 950.4 449.4 417.9 171.2 517.8 647.2 1697.3 1457.5 966.0 1021.7 1126.6 1689.4 879.8 873.0 1201.5 1179.4 2712.9 3.6 2268.6 561.5 597.3 1170.1 315.8 2031.4 1631.4 1518.4 586.5 1413.1 2339.5 1619.0 3.0 975.0 2212.8 967.9 1300.5 572.1 1056.8 1423.4 1416.9 1395.2 1610.8 1304.6 332.6 1342.7 3.2 1895.9 2665.6 4216.4 1051.1 727.7 1681.3 2032.0 1838.7 6021.8 2832.7 467.2 1077.8 403.6 618.1 1586.1 3842.2 5.3 1704.6 548.3 803.7 1048.1 578.5 1684.5 291.0 420.9 2953.4 891.8 1037.5 978.2 540.8 201.9 25.1 346.8 124.7 583.1 349.4 1341.5 723.8 367.2 250.9 1722.4 1124.1 31.7 459.0 95.2 427.7 1405.8 1431.2 509.1 528.2 593.7 617.0 484.1 581.9 564.4 575.4 556.2 537.8 582.5 517.8 89.8 141.1 316.4 68.2 242.2 73.0 439.5 1103.1 221.4 151.5 332.4 325.0 2502.3 298.8 433.9 474.5 68.8 1693.0 208.0 69.6 3306.5 18.4 10.5 224.3 325.0 227.3 92.4 361.2 39.4 314.9 870.1 299.4 222.8 309.4 268.6 412.6 155.7 11.2 612.9 141.3 55.6 152.2 956.2 189.8 104.3 34.3 274.6 174.8 179.7 33.7 197.3 277.6 159.6 47.7 40.3 99.7 84.3 415.2 303.1 310.6 0.2 3483.9 363.0 118.1 236.7 195.2 363.7 21.5 124.3 216.3 64.2 1639.5 398.1 1105.3 257.0 344.9 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;liver: 135.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1" "Cancer enhanced" "Detected in all" "liver cancer: 32.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.1" "Group enriched" "Detected in many" 45 "granulocytes: 11.1;monocytes: 4.8" "Cell line enhanced" "Detected in many" "Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol No NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626" "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favorable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 24.9 14.4 17.7 2.1 19.7 0.7 11.7 20.5 22.6 5.4 34.1 27.2 8.8 3.5 1.1 10.8 5.5 3.0 85.6 16.1 18.9 36.1 135.5 4.9 0.8 20.8 20.2 16.4 18.7 17.0 11.8 0.7 22.4 8.1 9.7 1.3 21.3 3.2 68.7 5.8 5.7 1.2 17.0 1.1 23.1 1.7 19.3 0.5 10.6 52.7 0.6 2.6 3.7 17.5 0.7 2.1 0.0 0.2 1.6 1.4 6.1 0.2 0.1 0.2 0.2 2.8 2.6 0.1 2.1 0.9 1.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.8 11.4 2.6 0.0 14.4 2.0 0.3 0.0 0.0 0.6 0.1 0.4 0.7 2.5 0.0 5.3 0.1 0.8 1.4 2.7 1.3 0.0 0.0 7.8 1.4 0.1 0.0 0.0 0.2 5.2 0.3 0.7 29.1 3.3 0.0 0.0 0.2 0.0 0.0 11.5 0.6 0.0 1.9 0.1 0.0 11.1 2.2 0.6 0.0 3.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 17.7 19.7 20.5 22.6 16.1 18.9 20.8 20.2 22.4 17.0 19.3 17.5 1.6 0.0 6.7 7.8 1.0 0.6 1.8 2.2 0.6 0.5 6.5 2.4 37.3 11.5 2.3 11.0 0.0 2.1 0.1 80.2 37.2 2.3 0.4 2.2 0.3 1.7 3.0 2.7 1.0 6.2 1.2 2.3 32.6 3.8 10.2 2.1 4.2 88.6 7.2 1.7 1.4 11.0 0.0 6.0 1.0 0.6 0.0 3.0 5.4 1.9 2.0 12.0 0.0 1.0 3.2 3.0 28.3 0.0 0.8 2.1 2.4 118.1 2.0 1.4 0.0 4.1 1.3 0.0 0.7 3.6 0.3 3.1 1.0 1.8 15.7 1.5 LETM1 SLC55A1 ENSG00000168924 "Leucine zipper and EF-hand containing transmembrane protein 1" O95202 4 1811479-1856156 "Human disease related genes, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011029, HPA011100" Supported Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA011029: AB_1852804, HPA011100: AB_1852802" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (3.85e-2)" "unprognostic (5.04e-2)" "unprognostic (5.48e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.37e-3)" "unprognostic (1.87e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.77e-4)" "prognostic favorable (8.90e-4)" "unprognostic (8.06e-3)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (2.42e-1)" 13.6 16.3 14.3 7.9 13.7 7.7 10.8 11.7 14.6 8.2 10.8 20.3 13.9 8.4 3.2 23.8 8.0 4.5 19.6 13.4 13.2 13.3 16.4 8.9 7.0 12.7 13.5 9.2 12.5 11.4 8.8 4.9 11.9 8.4 10.7 4.5 9.6 4.2 18.7 15.9 11.7 5.1 12.2 10.7 13.8 14.5 15.0 25.7 10.7 10.9 7.9 8.4 10.6 11.6 22.9 38.1 11.6 36.1 17.4 12.2 20.7 22.1 10.7 21.8 16.9 35.5 24.7 37.5 15.4 23.3 34.0 22.7 29.8 31.2 13.2 25.1 31.1 38.4 30.9 25.6 22.6 39.3 30.3 19.9 22.0 24.9 21.8 10.1 19.0 22.6 51.5 22.9 15.3 25.1 57.3 44.7 30.5 24.7 43.2 32.4 16.2 21.9 17.0 31.3 29.5 26.0 25.2 31.5 13.3 10.0 29.7 20.3 28.8 24.8 14.8 21.1 37.3 19.8 32.7 29.3 22.0 33.8 20.2 3.9 3.7 2.0 5.8 5.0 5.7 4.2 4.9 4.9 4.1 3.6 3.2 4.6 0.5 5.9 5.1 12.9 4.2 2.1 14.3 13.7 11.7 14.6 13.4 13.2 12.7 13.5 11.9 12.2 15.0 11.6 12.2 16.0 11.5 15.0 19.2 40.0 40.7 13.4 8.0 19.4 19.7 10.5 23.3 11.5 14.0 27.6 33.3 17.5 24.9 116.1 31.3 25.5 32.2 9.1 19.4 16.7 15.6 20.4 14.3 31.3 22.6 17.0 32.1 14.7 10.2 17.9 16.1 33.3 21.5 15.2 12.4 29.5 12.2 18.4 19.8 45.1 20.2 13.0 19.6 4.7 13.9 12.7 28.8 9.5 13.2 42.4 52.7 16.6 17.8 58.8 48.8 46.1 5.6 28.4 13.1 23.8 16.1 54.2 44.4 25.2 51.1 15.2 16.7 21.9 53.2 48.4 LIN52 C14orf46 ENSG00000205659 "Lin-52 DREAM MuvB core complex component" Q52LA3 14 74084796-74201235 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.5;Inhibitory neurons: 65.4;Oligodendrocyte precursor cells: 60.3;Oligodendrocytes: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000900, HPA001777" Uncertain Approved "Nuclear speckles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA000900: AB_2135058, HPA001777: AB_2666431" "unprognostic (2.34e-2)" "unprognostic (6.51e-3)" "unprognostic (1.86e-1)" "unprognostic (1.94e-1)" "unprognostic (7.90e-3)" "prognostic favorable (6.60e-4)" "prognostic unfavorable (6.08e-5)" "unprognostic (2.48e-3)" "unprognostic (9.34e-2)" "unprognostic (8.65e-2)" "unprognostic (1.39e-3)" "unprognostic (3.18e-1)" "unprognostic (1.74e-3)" "unprognostic (1.20e-2)" "unprognostic (8.28e-2)" "unprognostic (2.43e-2)" "unprognostic (1.04e-1)" 8.0 7.8 8.4 5.4 8.4 3.5 6.3 8.8 10.1 5.8 7.8 4.5 6.5 7.0 5.7 4.9 5.5 4.9 10.2 8.3 10.0 19.3 6.6 5.0 6.1 9.2 8.9 8.5 3.4 6.8 5.7 5.0 9.3 6.4 5.7 10.7 3.9 5.6 5.6 3.8 5.8 6.8 7.9 5.1 4.3 7.5 8.9 10.7 5.1 10.0 6.3 5.8 3.9 8.5 10.5 7.7 26.8 12.8 15.5 6.6 10.5 17.5 16.7 23.0 25.7 14.0 9.6 5.9 5.3 8.6 9.2 9.2 20.4 6.9 35.1 49.1 8.1 9.1 8.9 20.0 16.6 9.4 12.7 8.2 7.7 12.2 15.9 6.3 11.0 18.6 9.7 27.8 11.4 13.4 14.9 12.3 7.7 13.8 12.3 19.0 25.1 9.6 6.0 6.2 19.0 15.5 16.4 12.0 13.7 9.9 16.3 13.5 6.3 10.8 20.3 11.5 14.8 18.2 41.8 13.2 12.5 10.7 18.4 6.2 6.4 20.6 10.7 6.6 16.6 8.7 9.3 10.7 8.6 9.4 13.7 12.5 3.2 11.4 4.8 7.9 13.9 10.1 8.4 8.4 8.8 10.1 8.3 10.0 9.2 8.9 9.3 7.9 8.9 8.5 5.6 9.6 9.0 39.8 10.4 4.8 3.2 3.2 11.4 8.8 7.6 5.3 10.0 10.0 6.6 5.5 8.4 6.3 8.8 3.5 7.9 3.1 0.8 5.9 6.6 7.4 3.0 16.4 47.5 2.4 5.2 8.1 6.1 6.7 2.5 9.0 6.4 12.2 6.3 16.8 65.4 6.0 4.1 4.3 3.7 1.6 5.3 4.5 0.0 26.2 6.6 10.8 10.3 60.3 60.4 2.4 5.0 9.8 27.3 3.3 10.9 22.4 6.2 7.5 6.6 8.1 6.4 16.3 10.4 10.3 5.5 8.8 8.2 3.7 4.7 1.4 LRRFIP2 HUFI-2 ENSG00000093167 "LRR binding FLII interacting protein 2" Q9Y608 3 37052626-37183689 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035956, HPA042023" Uncertain Approved "Plasma membrane,Actin filaments" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA035956: AB_10671238, HPA042023: AB_2677802" "unprognostic (2.03e-3)" "prognostic favorable (6.31e-4)" "unprognostic (1.16e-2)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.97e-1)" "unprognostic (5.41e-2)" "unprognostic (1.82e-1)" "unprognostic (3.09e-2)" "unprognostic (2.56e-2)" "unprognostic (4.99e-3)" "unprognostic (1.98e-1)" "unprognostic (4.13e-3)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (4.84e-3)" "unprognostic (3.76e-2)" 23.4 24.0 43.7 20.1 46.9 44.3 22.3 43.6 49.0 46.0 33.6 38.3 35.4 31.8 19.7 52.6 25.8 22.0 75.8 38.8 44.4 24.0 48.5 27.0 18.1 43.4 42.0 27.4 19.2 33.3 18.6 20.8 44.8 41.0 34.2 36.0 28.5 24.3 97.9 37.0 36.2 31.5 41.0 45.0 26.5 71.8 46.4 18.8 27.5 45.3 23.2 24.2 40.9 60.9 56.6 30.8 34.9 27.7 45.5 69.3 30.5 149.9 148.2 82.6 94.3 29.0 25.3 22.2 24.0 145.4 40.8 28.8 25.8 74.2 134.3 49.7 20.2 39.8 44.0 28.6 64.8 31.9 23.3 31.1 52.1 107.8 110.4 45.8 58.2 34.0 32.3 37.8 69.5 14.4 27.2 17.0 23.0 23.0 39.2 13.0 99.2 22.6 58.4 21.7 12.6 19.9 57.9 53.0 49.4 28.0 30.6 32.6 56.5 63.1 42.6 93.4 71.5 29.1 57.1 33.9 37.1 28.1 91.4 20.5 21.4 33.8 8.8 14.9 11.3 9.7 9.3 9.5 14.1 8.5 6.8 8.3 19.2 16.9 26.9 7.9 13.0 11.7 43.7 46.9 43.6 49.0 38.8 44.4 43.4 42.0 44.8 41.0 46.4 60.9 47.8 28.9 36.5 98.6 29.1 136.1 143.0 41.3 113.8 36.3 64.7 53.2 123.1 38.6 53.7 23.9 29.2 29.2 28.7 117.2 64.6 89.8 516.2 78.9 44.0 59.9 54.0 60.0 169.8 94.3 46.1 57.4 37.8 127.3 52.6 29.4 56.7 58.8 24.9 122.8 197.7 45.6 28.5 35.6 128.3 330.7 42.3 48.2 74.7 62.8 67.7 51.9 30.9 130.7 309.0 109.9 90.1 57.6 45.8 325.6 125.8 46.1 36.2 51.9 39.5 32.4 72.8 159.9 73.4 139.3 170.5 39.3 34.1 90.0 66.0 303.2 LSM3 "SMX4, USS2, YLR438C" ENSG00000170860 "LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated" P62310 3 14178817-14201122 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 752.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044966 Approved Approved Nucleoplasm,Nucleoli NA NA 30000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoli Nucleoplasm "HPA044966: AB_2679159" "unprognostic (3.84e-3)" "unprognostic (7.00e-3)" "unprognostic (3.61e-2)" "unprognostic (2.87e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-1)" "unprognostic (2.94e-3)" "unprognostic (5.01e-2)" "unprognostic (2.70e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-2)" "unprognostic (8.07e-3)" "unprognostic (4.93e-3)" "unprognostic (5.57e-2)" "unprognostic (2.88e-1)" "unprognostic (1.46e-1)" "unprognostic (1.89e-3)" 12.6 10.8 12.1 11.0 12.6 18.9 12.6 13.2 16.6 8.7 12.1 12.1 12.4 9.1 10.4 12.1 8.2 6.5 17.4 12.6 12.7 23.3 18.4 8.2 12.9 12.3 12.0 9.4 9.5 11.0 9.0 10.3 12.5 9.8 11.2 10.7 9.2 8.3 30.1 10.1 12.9 8.1 12.4 9.7 10.5 12.3 12.6 16.8 10.7 22.4 11.8 10.3 8.7 13.2 36.0 28.6 30.1 31.3 13.8 16.0 76.3 29.0 19.3 36.6 34.8 32.6 27.6 39.5 23.5 20.3 25.7 16.4 34.5 28.4 36.0 37.5 42.3 41.8 38.1 31.5 7.1 47.3 29.0 12.0 20.2 36.8 15.6 16.4 19.1 34.0 45.9 30.7 27.4 41.5 50.4 64.2 52.1 40.2 38.5 27.4 37.3 43.5 34.6 36.7 16.8 27.2 33.2 46.1 28.6 34.3 53.2 59.7 17.3 23.3 37.2 28.3 50.6 21.4 67.3 73.6 29.5 45.9 33.8 44.1 18.9 30.0 14.8 23.7 17.7 27.3 17.1 17.5 18.3 21.7 18.4 19.7 17.8 21.9 20.3 28.7 22.9 25.7 12.1 12.6 13.2 16.6 12.6 12.7 12.3 12.0 12.5 12.4 12.6 13.2 114.2 67.3 94.3 11.4 118.2 97.8 135.4 328.8 115.5 52.5 124.2 171.4 263.4 155.8 164.6 126.9 18.8 391.8 114.2 158.2 485.2 220.4 337.8 111.2 97.8 104.5 104.7 111.9 8.3 265.5 409.6 120.0 67.8 115.2 138.2 142.4 128.8 234.8 235.5 55.5 8.3 195.4 175.0 132.9 115.0 153.1 140.1 119.6 97.8 5.6 202.4 180.7 170.0 7.1 13.3 219.2 196.7 139.9 154.2 110.2 203.9 752.2 122.3 68.2 105.2 111.5 117.9 288.5 295.5 150.8 101.2 318.4 93.6 144.6 205.7 177.2 LSM4 YER112W ENSG00000130520 "LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Z0 19 18306236-18323112 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 705.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040932 Uncertain Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA040932: AB_10795529" "unprognostic (2.71e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (7.42e-3)" "unprognostic (1.98e-1)" "unprognostic (4.09e-2)" "unprognostic (1.10e-3)" "unprognostic (9.80e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.34e-4)" "unprognostic (8.31e-3)" "unprognostic (1.25e-1)" "prognostic favorable (2.22e-4)" "unprognostic (2.51e-2)" "unprognostic (7.23e-2)" "unprognostic (8.08e-2)" "unprognostic (1.34e-1)" 56.5 130.5 97.9 31.8 101.8 62.9 55.1 99.7 111.7 52.7 111.4 86.4 57.6 51.6 36.3 100.5 52.8 17.4 108.2 102.8 104.9 118.8 122.8 60.9 41.4 99.6 102.5 50.6 57.4 48.5 72.5 35.5 105.1 64.2 45.2 33.1 55.2 39.6 149.1 70.4 77.1 27.3 95.9 71.1 78.4 126.8 104.8 78.9 62.2 89.4 38.9 62.1 59.7 97.3 294.3 151.2 252.3 226.2 95.4 91.4 291.8 132.2 113.6 167.9 158.7 137.0 305.5 172.0 274.5 139.0 152.5 192.3 276.4 274.5 127.1 201.1 524.0 156.1 247.0 167.5 94.9 148.9 89.2 83.3 160.5 156.9 182.9 94.2 139.6 248.6 333.0 172.3 177.3 479.7 411.0 321.6 327.1 419.2 475.4 229.4 112.0 320.5 212.9 102.0 283.8 264.9 113.0 141.3 204.2 174.8 140.4 157.8 81.0 98.0 113.2 244.3 250.5 160.2 147.7 204.4 131.4 289.3 170.4 171.5 223.2 163.8 148.3 258.5 182.5 163.5 158.3 154.4 252.8 164.5 169.7 171.4 18.4 220.4 205.6 359.0 166.9 283.9 97.9 101.8 99.7 111.7 102.8 104.9 99.6 102.5 105.1 95.9 104.8 97.3 76.8 28.9 38.8 7.5 85.1 67.4 92.4 183.1 46.7 72.0 141.7 134.9 53.2 74.4 90.5 115.8 14.6 270.4 95.8 179.1 299.3 196.7 280.8 102.8 55.1 75.7 124.4 109.8 11.5 182.1 489.1 67.9 68.8 96.9 117.4 115.7 54.3 89.3 288.4 58.9 11.1 194.5 154.6 85.4 129.0 705.7 62.4 109.1 104.9 7.5 243.2 115.6 130.7 7.1 13.4 159.3 205.5 47.4 98.3 153.1 225.3 347.7 94.6 73.0 46.0 38.5 80.7 203.1 378.6 125.5 71.9 170.5 87.7 174.2 237.1 119.9 MALSU1 "C7orf30, mtRsfA" ENSG00000156928 "Mitochondrial assembly of ribosomal large subunit 1" Q96EH3 7 23298739-23311729 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AN3-CA: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020487, HPA052210" Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA020487: AB_1845757, HPA052210: AB_2681762" "unprognostic (3.62e-1)" "unprognostic (3.68e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-3)" "unprognostic (5.24e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (1.83e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.68e-1)" 2.6 3.2 2.8 1.6 2.9 2.0 2.2 3.3 3.7 1.9 3.7 2.7 1.0 1.8 2.3 3.9 2.3 1.4 5.1 2.7 2.7 3.1 5.6 2.0 2.9 2.5 2.5 2.6 2.9 2.3 2.0 3.4 2.5 1.6 1.7 1.8 1.9 2.3 6.3 1.8 1.8 1.8 2.4 1.8 2.2 4.9 2.9 1.5 3.3 6.4 1.9 2.1 1.9 3.0 9.2 11.4 8.8 47.8 7.8 5.4 7.6 6.1 5.0 6.2 5.7 19.7 8.1 8.8 7.0 4.4 27.5 8.7 7.9 4.3 7.6 4.2 12.9 5.2 15.0 30.4 5.0 12.2 3.2 4.6 6.5 5.3 5.8 41.5 5.8 8.5 16.5 2.3 7.9 6.4 8.4 37.2 15.1 18.0 29.0 6.5 6.7 12.4 6.1 8.1 7.0 8.5 5.0 8.9 16.1 17.2 4.5 7.3 9.8 5.2 4.0 10.0 12.5 2.6 8.6 14.7 20.6 15.0 17.3 0.7 1.0 0.7 0.8 0.8 1.0 1.0 1.2 1.0 1.0 1.0 1.4 0.9 0.7 0.9 0.7 0.9 1.2 1.0 2.8 2.9 3.3 3.7 2.7 2.7 2.5 2.5 2.5 2.4 2.9 3.0 40.5 38.5 41.7 12.7 32.1 43.7 54.8 58.3 30.1 29.1 38.6 60.8 97.1 37.1 40.0 44.1 16.7 77.6 25.7 22.3 115.4 90.6 168.5 50.2 31.9 38.9 19.2 35.3 14.7 96.3 68.7 44.9 16.3 31.7 14.5 41.5 44.3 106.8 54.0 18.5 16.6 32.5 50.8 26.3 15.1 33.6 49.4 22.3 35.6 8.4 44.5 46.8 30.9 18.6 20.2 73.2 28.2 49.2 34.9 61.2 38.1 117.6 44.6 35.8 32.9 35.6 65.6 82.2 75.2 42.4 44.2 49.8 25.2 61.7 44.4 49.2 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124122 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 724.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol NA NA 140000 "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB003835: AB_562312, HPA051993: AB_2681685" "unprognostic (4.39e-1)" "prognostic favorable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favorable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favorable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 73.9 118.4 145.5 54.1 143.1 102.4 69.1 151.5 190.7 76.6 150.4 103.4 134.0 72.3 23.2 121.6 64.7 30.4 156.6 145.9 147.3 82.6 123.3 66.8 57.1 149.6 152.9 84.1 134.3 54.9 99.3 36.4 154.3 93.9 42.7 68.0 79.6 37.6 289.0 95.8 101.0 31.7 143.5 89.1 92.7 131.6 150.7 69.3 74.6 132.1 41.0 77.2 75.2 142.8 163.1 175.4 93.7 132.8 127.1 151.9 93.8 104.5 138.8 139.6 125.8 153.0 85.5 137.7 95.9 120.0 111.9 114.3 74.2 111.6 107.4 118.1 90.4 50.5 91.4 171.7 194.0 93.6 101.8 168.8 106.8 98.2 129.5 185.5 125.2 123.0 98.1 263.1 119.3 203.5 186.3 130.6 107.8 118.6 125.9 140.7 61.9 159.1 123.5 102.7 126.8 126.3 95.7 130.6 344.1 107.3 101.0 158.5 111.8 113.6 98.2 293.4 163.9 263.1 172.4 100.2 176.5 166.8 199.3 27.5 13.0 45.4 16.9 16.6 13.6 13.0 13.3 17.2 15.9 18.2 12.3 15.9 21.2 18.8 14.1 9.0 14.3 7.3 145.5 143.1 151.5 190.7 145.9 147.3 149.6 152.9 154.3 143.5 150.7 142.8 77.7 9.6 31.9 22.5 62.3 35.4 93.3 21.3 15.4 85.1 92.9 95.4 62.9 44.3 22.8 40.5 41.7 28.7 102.3 300.5 146.8 20.7 248.1 59.5 68.3 52.1 63.2 123.1 17.6 45.5 38.6 60.3 64.7 48.8 19.7 124.4 49.2 48.1 55.0 121.1 23.2 107.7 16.2 56.0 38.2 724.3 35.8 65.6 42.7 10.3 28.5 121.1 62.8 13.0 24.2 47.0 151.8 23.0 79.9 103.2 166.1 92.8 18.9 106.8 26.3 93.1 71.8 23.5 17.4 42.9 63.9 35.6 77.0 120.2 119.9 113.1 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 16.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in all" "HDLM-2: 211.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008910, HPA072462" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nuclear speckles" "CAB008910: , HPA072462: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favorable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 19.3 21.1 28.4 18.4 32.6 21.3 17.5 36.5 41.4 17.7 7.2 22.4 18.5 15.3 16.2 15.4 15.3 13.9 25.7 34.2 25.8 21.1 17.7 19.5 19.9 25.7 19.7 14.6 45.7 30.1 12.9 19.7 26.4 20.0 26.4 21.4 19.1 21.6 40.8 11.7 19.3 19.9 16.9 16.6 22.5 17.8 22.2 22.5 26.7 34.8 21.1 17.4 11.1 29.8 52.7 42.7 37.0 46.5 35.7 39.3 79.4 49.6 43.5 40.5 40.5 56.4 36.7 55.9 83.1 52.6 89.3 39.6 38.4 82.8 47.5 211.8 36.9 23.2 46.8 40.3 27.1 49.0 39.2 29.3 36.5 39.5 38.0 42.5 48.9 43.0 26.2 39.5 55.9 68.9 49.2 20.4 25.8 64.8 25.0 46.9 62.7 26.9 30.8 49.7 42.5 29.9 58.2 55.8 40.4 45.8 56.9 41.7 35.5 48.3 49.2 69.3 75.2 28.2 35.6 37.9 51.5 44.8 32.9 16.3 0.5 2.2 1.6 1.1 1.6 0.8 1.2 1.4 0.8 1.3 0.8 0.9 0.7 1.2 2.3 1.2 2.7 0.3 28.4 32.6 36.5 41.4 34.2 25.8 25.7 19.7 26.4 16.9 22.2 29.8 20.5 32.1 14.4 26.1 10.5 10.1 7.0 6.5 9.1 21.9 16.8 12.2 27.6 12.8 8.5 9.2 16.7 15.3 20.5 20.7 5.9 8.0 1.2 17.6 14.2 12.2 16.7 9.5 62.5 16.0 23.3 11.1 15.8 18.6 11.4 14.5 12.5 16.7 11.7 13.5 64.3 17.9 4.1 24.2 20.5 3.1 10.5 15.0 5.4 31.9 13.9 11.4 15.5 25.1 32.9 13.1 12.3 13.5 15.6 10.2 13.4 11.0 6.9 14.8 13.1 13.5 13.7 17.0 17.1 9.4 11.4 17.8 14.7 8.2 15.4 8.8 MAPKAP1 "MGC2745, MIP1, SIN1" ENSG00000119487 "MAPK associated protein 1" Q9BPZ7 9 125437393-125707234 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029091, HPA029092" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA029091: AB_10599732, HPA029092: AB_10601568" "unprognostic (6.65e-2)" "unprognostic (1.56e-1)" "unprognostic (1.31e-2)" "unprognostic (1.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.09e-1)" "unprognostic (5.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.68e-1)" "unprognostic (8.94e-2)" "unprognostic (2.59e-1)" "unprognostic (8.08e-2)" "prognostic favorable (7.23e-6)" "unprognostic (1.66e-1)" "unprognostic (2.04e-1)" "unprognostic (2.98e-1)" "unprognostic (4.27e-2)" 42.9 47.1 43.4 36.7 48.6 34.7 32.8 39.2 45.6 36.4 44.9 47.3 30.4 29.1 35.9 44.0 29.2 28.0 69.7 44.3 41.6 48.0 46.0 30.1 34.8 47.8 46.2 26.1 36.9 53.3 19.2 30.2 41.9 30.3 38.5 42.9 42.1 36.1 103.7 26.2 32.6 46.2 43.2 28.8 36.2 42.0 51.6 36.6 47.4 76.4 37.9 39.4 31.6 40.9 87.4 97.1 64.3 68.3 86.7 82.2 107.9 108.6 110.0 82.0 57.2 97.9 94.9 89.1 65.9 151.6 89.7 119.1 99.5 126.9 110.8 101.8 41.1 64.3 111.9 95.1 97.3 116.0 72.1 80.9 114.6 117.0 121.7 91.2 123.0 85.8 103.6 67.7 176.4 180.3 87.5 46.8 102.4 204.3 122.0 72.4 152.0 119.3 90.2 62.3 77.9 76.7 109.7 100.9 70.0 86.6 115.8 67.1 79.7 115.3 76.1 140.5 182.5 86.1 225.2 89.9 165.5 52.5 127.6 4.4 6.1 5.7 4.3 6.0 5.9 8.2 4.7 4.8 4.9 7.4 4.1 7.1 19.1 5.8 5.6 7.2 5.8 2.5 43.4 48.6 39.2 45.6 44.3 41.6 47.8 46.2 41.9 43.2 51.6 40.9 22.3 12.8 17.0 64.6 33.5 15.8 30.2 15.3 25.6 25.6 30.6 24.1 68.3 22.8 27.5 14.7 41.7 35.4 31.7 28.9 54.8 48.3 80.2 26.2 42.6 27.1 9.6 22.3 82.6 65.6 50.9 27.0 32.1 29.3 17.7 31.2 19.6 34.5 50.7 32.0 80.1 20.8 22.4 29.5 23.4 116.9 19.0 37.3 23.2 59.0 55.1 30.1 35.0 97.0 96.4 59.2 20.1 17.7 32.3 45.2 27.2 84.6 14.6 26.2 6.6 29.1 33.0 75.4 71.4 29.1 19.5 50.9 29.5 38.4 27.6 37.8 MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1349.1;tongue: 1843.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1926.9;Proximal tubular cells: 1428.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434" "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favorable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" 274.6 213.6 235.9 86.7 249.7 79.1 137.9 245.9 353.6 89.6 230.2 167.7 154.7 82.0 161.3 125.3 114.5 87.2 1349.1 253.2 261.5 371.6 266.3 89.8 131.9 248.5 218.3 80.4 69.9 411.8 107.2 92.5 253.3 125.5 190.9 240.7 122.0 142.0 792.5 87.7 133.1 171.5 215.7 71.6 192.6 70.5 259.1 170.4 125.5 1843.8 165.4 131.5 62.8 237.7 268.2 219.5 257.8 173.2 369.6 280.9 282.3 215.1 295.9 300.6 304.1 252.5 215.4 355.2 112.8 264.1 358.8 214.3 303.0 355.0 425.5 207.6 253.1 337.0 173.2 376.8 202.1 384.1 223.9 277.7 241.3 271.5 152.7 236.2 235.3 308.1 183.7 217.3 395.1 157.8 300.6 317.5 158.0 376.3 266.5 235.2 349.7 310.5 460.9 251.0 249.9 153.6 182.5 257.7 384.1 205.6 191.9 341.9 149.6 220.3 211.9 187.1 252.9 264.6 264.8 407.6 266.2 312.2 184.1 271.3 186.3 200.2 202.7 267.8 218.8 258.5 236.6 224.6 241.0 258.5 230.3 221.6 28.1 214.6 253.4 184.3 320.9 321.2 235.9 249.7 245.9 353.6 253.2 261.5 248.5 218.3 253.3 215.7 259.1 237.7 44.4 60.9 54.3 54.9 78.7 81.6 109.4 562.9 50.7 165.4 81.0 86.7 1926.9 95.8 227.2 134.3 70.9 248.7 78.4 128.4 630.0 186.2 12.4 116.1 72.6 61.0 62.8 62.9 120.2 108.1 257.0 134.7 112.7 68.8 80.5 95.0 36.0 153.2 397.0 122.8 130.0 115.9 380.5 85.2 65.8 15.1 100.0 98.4 177.9 43.1 155.0 136.3 73.2 51.3 58.8 91.3 99.8 109.1 82.1 48.8 177.4 1428.3 224.5 164.1 59.2 68.3 167.8 58.0 65.6 82.7 84.0 149.5 84.3 137.4 167.8 102.6 MED11 "HSPC296, MGC88387" ENSG00000161920 "Mediator complex subunit 11" Q9P086 17 4731428-4733608 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056669 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear bodies" "HPA056669: AB_2683204" "unprognostic (4.01e-2)" "unprognostic (2.34e-2)" "unprognostic (7.91e-2)" "prognostic favorable (1.86e-5)" "unprognostic (8.24e-2)" "unprognostic (5.47e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.82e-2)" "unprognostic (3.86e-2)" "unprognostic (2.10e-3)" "unprognostic (1.09e-1)" "unprognostic (1.12e-3)" "unprognostic (4.84e-2)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (8.61e-2)" 20.5 41.3 28.6 22.5 32.0 11.2 20.3 32.3 33.8 21.1 28.2 25.4 27.2 18.9 25.3 29.2 24.4 19.0 29.5 28.2 30.5 32.7 38.6 22.9 28.5 31.9 31.2 16.8 29.0 35.6 19.1 16.4 31.6 23.3 23.4 17.2 26.6 19.5 39.0 27.2 26.5 16.9 30.4 34.5 30.6 16.2 31.3 25.3 22.4 32.9 26.5 22.3 21.3 35.3 26.2 73.5 26.9 27.8 28.6 34.6 20.7 18.4 30.8 26.4 33.0 25.6 19.7 35.7 18.9 22.3 17.2 38.8 27.1 51.9 20.5 42.5 63.1 17.8 42.6 40.6 17.7 12.9 20.7 30.1 35.6 28.3 17.3 28.2 30.3 36.4 18.1 26.5 23.4 37.6 24.8 16.8 16.0 39.3 23.6 24.5 19.7 23.3 54.3 27.5 10.9 18.1 23.7 31.5 18.5 22.0 28.4 15.1 18.1 14.1 14.1 27.4 29.3 12.5 11.8 14.2 24.4 22.0 18.8 49.1 31.0 79.3 41.6 45.6 45.4 62.8 40.8 41.8 31.0 61.9 48.3 53.1 136.3 40.9 68.0 49.8 33.7 38.5 28.6 32.0 32.3 33.8 28.2 30.5 31.9 31.2 31.6 30.4 31.3 35.3 12.5 6.4 23.5 7.8 31.5 12.2 28.8 42.6 19.4 22.1 20.0 17.8 15.1 32.9 32.3 14.7 10.4 45.4 34.3 32.8 64.6 37.0 1.2 35.1 24.8 15.8 10.8 13.5 5.5 35.3 34.2 17.3 28.5 25.0 29.1 9.3 22.5 29.4 33.8 30.3 7.2 30.9 48.8 31.5 21.1 3.8 17.4 25.5 10.6 5.6 44.6 20.9 50.4 5.0 14.6 22.4 51.1 13.9 18.8 22.9 66.4 99.5 36.9 26.6 19.7 16.5 18.2 56.6 49.9 31.3 18.8 25.0 27.3 33.8 29.7 28.6 MED9 "FLJ10193, MED25" ENSG00000141026 "Mediator complex subunit 9" Q9NWA0 17 17476994-17493221 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056415 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Midbody "HPA056415: AB_2683120" "unprognostic (1.81e-2)" "unprognostic (4.58e-2)" "unprognostic (2.65e-1)" "unprognostic (3.48e-3)" "unprognostic (1.27e-1)" "unprognostic (2.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.21e-2)" "unprognostic (4.23e-1)" "unprognostic (7.65e-2)" "prognostic favorable (4.18e-5)" "unprognostic (3.96e-2)" "prognostic favorable (2.83e-9)" "unprognostic (2.26e-3)" "unprognostic (2.29e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-1)" 9.3 14.9 21.6 4.9 23.0 10.6 10.3 20.6 28.0 12.4 19.2 11.3 8.2 12.1 11.9 10.2 8.6 4.6 32.7 22.5 21.0 20.4 23.6 7.3 6.8 21.8 22.1 9.4 10.0 18.3 12.8 5.7 20.6 11.8 7.4 9.9 12.9 8.5 27.3 14.2 9.4 5.8 20.9 10.4 12.4 10.9 22.3 11.6 13.8 41.5 6.7 8.8 9.4 21.8 12.0 15.0 12.7 13.7 10.0 9.0 11.0 9.6 11.9 14.5 13.0 22.0 5.9 14.7 10.8 9.9 8.8 15.3 16.3 13.2 13.5 9.6 26.3 9.0 10.0 15.9 10.8 7.2 7.5 14.6 12.3 12.2 12.5 10.8 10.0 21.3 10.7 6.7 9.7 10.1 32.7 14.9 11.7 24.8 15.4 24.8 28.7 9.8 13.0 8.4 8.2 13.0 12.6 9.8 21.7 47.6 11.6 9.3 6.8 10.6 12.3 18.6 15.3 12.4 9.9 8.2 13.3 12.5 11.5 2.6 7.0 11.8 9.3 9.5 12.3 9.9 9.7 9.7 7.7 9.1 10.2 11.4 2.3 10.7 12.4 12.5 10.2 7.8 21.6 23.0 20.6 28.0 22.5 21.0 21.8 22.1 20.6 20.9 22.3 21.8 6.0 3.2 4.4 10.1 5.8 4.6 8.9 5.5 5.2 25.9 8.2 6.7 19.6 10.0 5.0 9.2 14.6 8.6 8.1 9.1 11.7 6.6 8.7 6.0 6.3 6.0 15.7 4.2 14.4 4.5 5.8 5.6 11.7 8.8 0.0 14.5 7.5 5.5 6.1 16.8 12.9 9.6 8.2 4.4 2.8 8.9 5.6 4.0 1.8 1.9 4.7 24.1 10.3 14.1 6.5 3.3 5.7 9.4 7.2 8.4 9.5 6.1 4.0 25.0 0.0 6.0 6.9 10.9 29.9 5.6 4.8 9.6 6.6 13.4 8.1 9.0 METTL5 HSPC133 ENSG00000138382 "Methyltransferase like 5" Q9NRN9 2 169810081-169824931 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038223 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Cytosol "HPA038223: AB_10672509" "unprognostic (2.55e-2)" "unprognostic (8.41e-2)" "unprognostic (4.73e-1)" "unprognostic (3.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (6.64e-5)" "unprognostic (2.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.24e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (3.06e-8)" "unprognostic (8.53e-2)" "unprognostic (1.70e-1)" "unprognostic (1.95e-2)" "unprognostic (6.87e-3)" 51.1 39.5 41.3 27.7 42.5 34.0 50.2 41.0 57.0 30.4 36.1 53.7 29.4 29.4 63.0 36.6 29.2 25.1 65.5 41.9 45.2 38.5 46.9 24.1 35.4 41.0 42.5 25.7 54.1 36.7 30.2 30.7 42.4 32.5 42.2 30.5 47.1 32.1 92.9 32.7 33.0 36.6 43.7 26.4 43.0 24.3 45.1 30.8 37.7 73.5 38.4 42.3 31.5 45.0 97.1 52.5 74.6 83.1 66.9 99.6 122.6 80.1 74.8 95.4 76.1 164.2 111.2 122.8 95.0 66.0 126.8 98.5 103.0 167.9 133.3 95.3 73.8 185.8 40.6 181.8 90.9 235.9 87.6 73.6 220.2 121.2 147.7 99.4 90.0 165.8 176.0 99.9 123.1 93.8 113.7 190.5 101.4 125.5 98.5 113.7 70.0 190.6 167.0 87.5 90.5 67.6 51.5 80.2 146.0 84.2 75.7 104.6 62.2 103.4 84.5 65.4 104.3 97.0 158.8 206.3 86.3 113.7 95.3 45.5 26.0 21.1 39.9 32.5 61.5 65.0 54.8 53.9 32.0 56.3 56.5 52.3 7.7 45.3 31.8 49.5 57.8 34.8 41.3 42.5 41.0 57.0 41.9 45.2 41.0 42.5 42.4 43.7 45.1 45.0 67.1 12.8 28.8 6.8 49.1 38.6 88.9 105.2 47.8 24.8 64.0 111.4 83.1 50.1 65.4 44.1 16.7 96.1 43.2 36.1 111.6 115.6 3.9 61.0 34.8 48.6 60.6 70.9 10.8 146.2 117.4 43.8 24.5 43.1 46.3 35.1 46.4 49.5 77.2 23.5 11.0 66.7 59.0 36.9 33.3 8.7 50.4 35.9 55.2 9.4 53.7 51.6 53.5 7.1 13.2 149.7 48.8 60.2 48.1 92.5 72.2 115.8 61.3 23.0 52.6 47.2 66.5 49.2 97.4 56.2 40.9 39.1 47.6 48.4 69.3 89.2 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2092.0;Syncytiotrophoblasts: 2371.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 793.9;OE19: 781.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA053311: AB_2682108, HPA077929: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 260.2 163.3 218.0 57.7 224.9 126.2 196.5 245.4 273.1 96.6 214.1 219.6 358.6 91.9 520.6 97.6 112.3 114.4 770.2 232.6 258.0 254.3 166.8 117.5 48.9 239.5 228.8 118.0 90.1 139.1 86.1 173.2 248.3 113.4 217.8 89.9 164.0 114.8 568.0 87.8 301.6 118.8 227.4 54.4 163.0 64.2 230.3 51.9 142.9 578.7 47.7 107.2 90.0 240.5 178.2 128.0 150.0 106.1 533.4 312.1 653.1 158.1 244.2 119.1 205.2 126.8 219.1 10.9 117.1 198.6 117.8 204.7 36.2 155.2 118.5 793.9 94.5 27.1 84.7 60.4 144.9 45.0 58.9 284.2 107.5 178.0 62.3 239.4 202.0 54.2 72.3 65.6 233.6 37.0 48.9 97.4 292.3 781.6 165.8 44.8 63.0 22.2 599.8 159.4 104.1 134.2 148.7 181.1 313.2 308.4 139.1 215.9 174.7 135.8 82.6 92.9 110.8 49.7 37.0 5.8 239.8 109.7 92.3 44.8 172.9 81.2 107.2 150.2 107.9 79.3 130.5 117.3 138.0 78.2 81.4 89.1 32.3 62.3 195.0 58.2 125.5 185.0 218.0 224.9 245.4 273.1 232.6 258.0 239.5 228.8 248.3 227.4 230.3 240.5 915.1 102.5 164.8 48.3 87.6 228.3 251.8 603.8 111.0 144.6 177.0 267.6 670.1 301.7 292.6 557.3 266.9 2092.0 96.5 500.3 1001.8 380.2 18.2 325.6 132.6 268.0 152.8 785.4 75.8 425.9 1327.2 300.3 193.7 257.7 91.8 519.5 257.7 295.0 837.4 131.2 86.4 302.9 374.3 130.0 243.1 46.1 388.0 234.9 519.4 43.1 296.6 257.9 87.6 45.8 90.6 401.8 613.9 399.8 92.9 173.9 1004.1 1227.6 459.9 162.5 506.2 197.5 652.1 23.1 40.4 157.1 232.6 2371.4 123.1 288.6 440.7 237.6 MICOS10 "C1orf151, FLJ36999, Mic10, MINOS1, MIO10, RP5-1056L3.2" ENSG00000173436 "Mitochondrial contact site and cristae organizing system subunit 10" Q5TGZ0 1 19484403-19629821 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 453.9;Cytotrophoblasts: 283.4;Extravillous trophoblasts: 279.7;Hofbauer cells: 531.0;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA059930 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA059930: AB_2684167" "unprognostic (3.84e-2)" "unprognostic (8.74e-3)" "unprognostic (2.66e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.88e-1)" "unprognostic (8.74e-2)" "unprognostic (3.96e-1)" "unprognostic (1.37e-1)" "unprognostic (2.43e-2)" "unprognostic (1.24e-3)" "unprognostic (7.13e-2)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "prognostic favorable (8.11e-4)" 4.9 5.0 11.5 3.1 11.6 2.6 6.0 11.9 13.6 8.6 11.0 9.3 5.1 7.0 6.2 7.2 7.3 4.1 12.6 11.5 13.1 9.7 4.0 4.6 4.3 12.9 11.7 6.4 5.2 11.1 9.5 4.0 13.1 8.5 8.8 5.9 5.1 8.3 14.3 4.8 6.0 7.0 11.3 3.6 6.7 3.4 13.8 4.0 6.5 16.8 5.9 7.0 6.2 11.1 10.0 13.3 7.3 8.4 13.7 13.6 4.5 8.3 9.6 9.5 10.1 9.3 8.7 8.1 6.8 11.0 7.7 6.9 12.8 10.9 15.2 12.7 9.1 7.1 21.2 13.0 6.0 11.6 5.1 10.7 17.5 9.5 11.6 7.4 14.1 6.0 15.8 5.9 14.4 17.2 5.8 15.0 6.2 12.5 16.7 5.7 9.3 10.8 23.3 5.9 15.4 6.7 9.6 7.4 7.1 5.7 7.1 6.7 9.3 7.4 5.7 9.5 8.3 3.8 6.8 8.4 5.8 21.3 7.1 3.8 4.8 5.7 3.6 6.6 3.3 4.3 4.9 4.1 5.1 4.1 6.3 4.5 3.2 2.3 7.0 5.0 4.9 5.9 11.5 11.6 11.9 13.6 11.5 13.1 12.9 11.7 13.1 11.3 13.8 11.1 63.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 453.9 0.0 0.0 0.0 0.0 283.4 25.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 279.7 52.8 0.0 0.0 0.0 0.0 0.0 0.0 531.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 183.5 5.3 0.0 0.0 0.0 MICOS13 "C19orf70, MIC13, P117, QIL1" ENSG00000174917 "Mitochondrial contact site and cristae organizing system subunit 13" Q5XKP0 19 5678421-5680516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 344.8;Cytotrophoblasts: 154.4;Extravillous trophoblasts: 196.7;Hofbauer cells: 242.2;Syncytiotrophoblasts: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042672 Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria Nucleoplasm "HPA042672: AB_10794531" "unprognostic (9.54e-2)" "unprognostic (4.90e-3)" "unprognostic (3.04e-1)" "unprognostic (3.21e-3)" "unprognostic (1.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (2.53e-3)" "unprognostic (2.14e-2)" "unprognostic (9.32e-2)" "unprognostic (2.50e-2)" "unprognostic (1.57e-1)" "prognostic favorable (7.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.94e-2)" "unprognostic (2.27e-1)" "unprognostic (5.47e-2)" 71.0 68.8 139.7 48.4 143.6 54.1 59.3 153.6 180.2 44.4 137.0 76.5 78.6 46.9 44.0 86.9 67.3 53.8 271.2 141.2 154.5 93.5 78.3 44.2 60.4 148.7 143.8 44.7 86.7 97.4 59.8 37.9 147.1 50.1 40.7 18.6 95.3 60.7 279.3 59.7 66.7 43.8 142.0 45.0 61.8 149.2 151.4 38.8 57.9 186.5 35.2 61.3 49.3 146.7 175.7 167.9 43.4 87.6 98.3 117.1 58.7 100.7 121.0 142.6 120.3 132.6 85.2 82.0 157.6 105.2 65.3 124.7 25.8 175.5 34.6 128.9 311.9 76.1 101.2 153.4 162.5 105.8 79.2 133.0 157.9 71.5 92.6 68.0 104.9 112.5 120.5 220.6 101.2 186.3 145.7 129.2 45.1 118.5 474.3 79.5 57.8 286.7 145.3 126.1 111.5 134.8 37.8 198.1 152.2 25.2 128.3 123.8 87.4 121.9 50.5 217.4 169.2 315.8 280.6 66.9 174.5 183.6 126.0 76.8 214.3 77.8 198.9 274.7 237.5 291.6 228.5 225.8 261.4 235.7 222.8 211.3 29.6 192.1 238.8 302.5 211.1 278.1 139.7 143.6 153.6 180.2 141.2 154.5 148.7 143.8 147.1 142.0 151.4 146.7 44.6 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 344.8 0.0 0.0 0.0 0.0 154.4 24.5 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 196.7 46.9 0.0 0.0 0.0 0.0 0.0 0.0 242.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 125.9 5.8 0.0 0.0 0.0 MKKS BBS6 ENSG00000125863 "McKusick-Kaufman syndrome" Q9NPJ1 20 10401009-10434222 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Chaperone "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041071, HPA044233" Enhanced Supported Centrosome NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Centrosome "HPA041071: AB_10960408, HPA044233: AB_10962986" "unprognostic (9.53e-2)" "unprognostic (6.70e-2)" "unprognostic (3.00e-1)" "unprognostic (3.17e-2)" "unprognostic (1.84e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (9.84e-5)" "unprognostic (5.54e-2)" "unprognostic (1.19e-1)" "unprognostic (2.58e-1)" "unprognostic (1.01e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.79e-9)" "unprognostic (3.69e-1)" "unprognostic (6.18e-2)" "unprognostic (1.63e-2)" "unprognostic (3.01e-1)" 12.0 13.3 15.3 6.7 16.6 1.9 12.3 17.9 19.2 14.3 19.6 18.9 17.3 12.6 13.7 12.7 13.1 12.7 20.6 17.0 17.2 28.8 26.0 9.9 8.4 16.4 15.2 13.8 12.4 25.5 14.8 9.6 17.0 15.0 19.4 22.8 13.0 15.4 25.4 9.3 14.5 14.3 15.4 11.8 13.9 16.2 16.3 12.2 17.6 40.6 10.7 14.4 13.3 16.0 18.9 23.3 21.7 32.9 23.3 20.9 6.7 12.7 14.4 16.6 13.3 7.7 9.6 16.2 5.3 12.4 30.0 25.0 27.6 25.1 20.6 2.9 10.4 37.1 5.8 20.9 15.8 23.4 7.5 18.5 47.5 16.0 31.7 28.0 13.5 14.8 18.8 11.7 19.7 7.1 22.3 14.2 15.6 60.8 16.4 13.2 21.5 14.5 25.7 8.6 33.0 20.9 11.9 61.3 29.7 14.5 16.8 15.5 6.3 14.6 12.4 17.8 23.3 8.6 36.3 6.9 12.1 24.3 15.3 19.5 16.0 13.4 11.7 14.2 13.8 11.3 13.0 9.9 16.8 7.8 15.1 14.1 7.9 11.9 16.9 10.8 11.0 16.4 15.3 16.6 17.9 19.2 17.0 17.2 16.4 15.2 17.0 15.4 16.3 16.0 15.0 3.2 17.9 20.5 29.8 33.9 56.5 143.1 39.9 39.1 11.5 13.7 225.7 118.7 67.0 9.2 12.5 101.6 50.3 116.4 68.4 27.0 95.4 14.7 11.5 41.2 71.2 43.5 30.2 19.8 83.4 40.1 37.8 11.5 22.8 9.1 57.5 182.4 127.1 69.0 36.1 90.0 89.5 62.5 67.5 41.7 62.4 34.5 49.8 11.2 51.1 70.7 55.6 25.6 24.7 17.6 92.9 63.9 31.5 87.4 99.6 47.4 54.7 40.1 52.6 43.9 51.5 229.1 73.6 86.4 42.8 96.9 23.5 13.0 100.7 75.5 MLST8 "GbetaL, GBL, Lst8, Pop3" ENSG00000167965 "MTOR associated protein, LST8 homolog" Q9BVC4 16 2204248-2209453 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019935, HPA041841" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Golgi apparatus, Cell Junctions" "CAB019935: AB_561447, HPA041841: AB_2677701" "unprognostic (2.19e-1)" "unprognostic (7.68e-2)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (3.35e-3)" "unprognostic (1.74e-1)" "unprognostic (8.17e-3)" "unprognostic (1.52e-1)" "unprognostic (5.77e-2)" "unprognostic (5.70e-3)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "prognostic favorable (7.60e-4)" "unprognostic (8.74e-2)" "unprognostic (1.20e-1)" "unprognostic (2.29e-1)" "unprognostic (5.48e-2)" 16.7 29.4 31.5 9.8 31.8 13.3 17.1 31.4 51.1 16.0 25.5 17.3 12.5 15.5 5.6 24.8 14.6 9.1 25.0 32.4 29.9 26.0 31.3 13.3 10.5 32.0 31.0 19.4 35.8 13.3 19.8 11.1 32.4 20.5 4.6 5.7 19.7 8.0 39.4 22.2 15.6 4.5 29.4 16.5 22.3 33.6 32.5 9.7 22.4 21.8 5.2 16.7 15.5 34.1 20.5 61.9 23.1 60.5 29.6 20.8 38.2 17.9 20.4 26.7 22.9 83.4 29.5 51.3 40.6 20.1 12.7 25.8 23.1 51.4 3.1 39.4 113.4 36.0 61.0 51.7 44.7 57.3 49.7 29.7 34.8 31.7 41.8 22.6 28.6 74.1 54.9 35.9 14.8 89.4 55.5 74.9 47.3 18.1 57.4 55.6 23.4 93.8 20.7 13.4 73.5 40.1 26.6 62.1 46.3 8.7 38.6 54.2 22.4 33.5 38.9 27.3 23.7 43.0 26.4 57.8 17.6 47.5 29.9 0.0 25.0 4.2 14.1 29.9 11.8 14.4 13.1 15.2 24.6 12.5 15.0 15.1 2.8 14.6 30.1 13.3 13.1 20.7 31.5 31.8 31.4 51.1 32.4 29.9 32.0 31.0 32.4 29.4 32.5 34.1 11.5 6.4 16.0 10.4 24.6 14.7 16.2 29.6 21.6 31.5 24.7 29.8 3.3 15.7 16.2 16.5 20.9 63.2 13.0 44.6 35.2 34.4 48.7 9.6 13.1 16.8 28.8 26.9 8.9 42.6 50.4 19.2 42.8 11.2 8.2 26.8 20.3 16.7 46.9 30.3 8.4 37.9 22.4 19.1 14.6 105.4 14.9 18.4 17.8 1.0 28.0 29.4 19.6 5.5 5.9 28.6 37.9 15.1 34.1 17.9 43.2 36.3 11.1 30.6 19.7 11.6 16.5 34.7 28.2 29.4 15.5 52.7 15.4 26.8 49.3 17.4 MLYCD "hMCD, MCD" ENSG00000103150 "Malonyl-CoA decarboxylase" O95822 16 83899115-83951445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 21.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 97.5;Cone photoreceptor cells: 125.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031625 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA031625: AB_10602028" "unprognostic (6.23e-2)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (6.23e-2)" "unprognostic (1.84e-4)" "unprognostic (2.33e-1)" "prognostic favorable (2.61e-7)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (9.56e-2)" "unprognostic (1.51e-3)" 2.5 2.1 1.9 1.0 2.5 0.4 1.4 1.5 2.4 1.1 2.7 1.7 1.7 1.3 1.2 1.0 1.4 0.7 9.5 1.7 1.9 2.7 5.7 1.2 1.2 2.5 2.5 1.9 5.1 2.0 1.2 0.9 2.0 1.2 1.7 2.4 2.1 1.5 8.2 1.0 1.4 1.2 1.6 1.0 2.5 1.3 3.2 1.0 1.5 21.5 0.9 1.6 0.9 2.5 0.6 1.9 1.6 1.9 2.5 0.9 2.9 0.8 1.2 0.7 0.4 0.9 1.5 0.1 2.4 1.2 2.6 1.5 1.4 0.6 0.7 0.8 1.9 0.9 0.8 1.9 3.0 1.2 2.1 1.1 1.4 0.4 0.4 1.3 0.8 1.4 1.4 0.4 1.1 2.4 0.7 2.7 1.6 2.7 0.4 2.2 1.1 1.1 1.6 1.1 1.4 0.9 3.0 1.1 2.4 2.1 3.4 2.5 0.6 1.8 0.3 1.0 0.2 2.1 1.3 2.0 1.0 0.9 1.9 0.5 0.1 0.5 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.9 2.5 1.5 2.4 1.7 1.9 2.5 2.5 2.0 1.6 3.2 2.5 6.1 6.4 7.3 8.5 10.9 2.0 7.4 1.5 4.6 25.2 7.2 5.2 97.5 17.2 5.5 23.9 125.1 20.2 10.6 12.9 31.3 5.7 4.6 10.4 6.9 8.2 10.2 9.1 3.1 5.5 11.1 10.5 15.3 8.7 5.7 20.1 12.8 46.2 12.3 16.8 6.2 15.2 4.1 10.1 2.0 8.6 14.6 8.2 3.6 3.7 7.7 14.7 27.8 12.5 8.2 6.7 13.1 19.5 6.5 10.4 19.4 19.4 2.4 53.3 6.6 19.0 8.1 12.1 14.4 5.2 2.0 8.2 9.0 17.5 17.1 8.6 MMACHC "cblC, DKFZP564I122" ENSG00000132763 "Metabolism of cobalamin associated C" Q9Y4U1 1 45500300-45513382 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 17.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027394, HPA027399, HPA027402" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA027394: AB_10601669, HPA027399: AB_10601987, HPA027402: AB_2672255" "unprognostic (3.34e-1)" "unprognostic (1.63e-1)" "unprognostic (7.03e-3)" "unprognostic (3.14e-2)" "unprognostic (4.05e-1)" "unprognostic (1.16e-2)" "unprognostic (9.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-2)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.61e-3)" "unprognostic (2.08e-3)" "unprognostic (8.83e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" 2.0 3.1 3.3 1.7 5.3 1.2 3.5 5.1 4.2 2.9 2.3 3.7 3.3 1.7 3.0 2.8 3.5 1.3 6.9 3.4 5.1 3.5 17.4 1.2 1.8 4.1 5.6 3.5 2.9 5.5 1.3 1.5 3.9 2.0 4.4 2.1 5.0 2.4 10.8 2.0 2.4 2.3 3.5 1.6 2.3 4.3 5.6 2.2 2.3 6.6 2.0 1.7 1.5 6.0 7.7 3.9 6.6 10.0 6.1 3.7 8.1 5.9 3.9 10.5 9.4 8.3 4.7 12.0 7.4 4.9 2.0 6.2 12.3 14.0 9.6 3.3 11.4 9.4 6.5 9.2 5.8 13.5 3.3 5.3 7.8 11.6 12.6 3.7 5.1 12.5 10.8 6.7 8.1 8.2 9.1 4.3 10.9 8.8 8.9 11.1 2.7 13.2 6.2 6.0 10.5 5.4 8.8 14.5 19.3 4.9 8.3 4.6 2.3 7.3 9.9 8.3 3.3 9.9 8.5 6.9 5.3 6.4 6.9 2.3 0.5 0.5 0.5 0.8 0.8 0.7 0.7 0.4 0.6 0.6 1.3 0.6 0.9 0.8 2.7 1.3 0.4 0.4 3.3 5.3 5.1 4.2 3.4 5.1 4.1 5.6 3.9 3.5 5.6 6.0 1.1 3.2 5.5 1.6 2.1 0.1 1.8 0.8 5.7 1.3 2.7 1.5 9.8 4.3 2.2 1.8 0.0 3.7 0.6 2.8 5.9 1.3 1.0 3.6 4.8 1.5 4.2 4.8 2.6 1.4 4.3 3.6 7.1 3.2 2.5 2.9 2.5 22.9 3.3 3.3 2.7 3.2 2.0 3.2 0.9 1.2 1.8 2.7 0.0 0.0 0.6 1.4 3.1 1.5 5.3 1.8 2.3 1.5 10.4 1.7 2.0 4.6 1.2 5.2 0.0 5.0 2.4 7.4 2.1 11.5 0.1 2.7 2.4 3.9 5.8 1.8 MOCS2 "MOCO1, MOCS2A, MOCS2B" ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 573.2;Proximal tubular cells: 281.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear speckles" "HPA037679: AB_2675604, HPA037680: AB_10673635" "unprognostic (3.27e-1)" "unprognostic (3.11e-2)" "unprognostic (2.82e-1)" "unprognostic (8.37e-3)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" "prognostic favorable (3.68e-6)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.86e-2)" 48.7 79.4 79.1 24.9 84.9 9.1 42.1 80.3 107.6 34.7 74.4 41.9 40.8 30.0 45.9 35.2 26.5 31.3 87.0 84.3 86.3 114.8 126.2 28.2 26.1 79.2 80.5 43.5 42.4 89.6 30.5 35.9 82.4 36.8 32.3 59.3 48.9 44.9 109.3 16.6 40.2 34.4 85.6 23.6 37.2 26.0 88.0 28.3 55.4 111.8 25.2 30.8 24.6 87.4 79.4 62.7 42.9 109.9 85.0 83.2 51.6 99.5 91.9 74.4 89.8 79.7 56.5 76.7 143.5 69.9 127.1 45.0 91.7 96.7 117.2 19.6 84.8 61.7 58.2 75.9 94.4 65.0 43.0 65.1 41.7 91.7 83.5 81.0 85.1 101.4 58.7 44.2 129.5 115.5 72.7 31.8 37.0 34.2 130.1 36.0 93.0 67.0 144.1 56.6 29.4 33.7 69.4 57.3 72.9 56.9 107.2 15.4 55.6 76.9 81.0 69.1 120.5 49.4 84.8 91.5 106.7 16.8 125.1 14.5 21.8 15.6 36.9 26.9 46.2 37.5 42.7 42.8 29.8 40.5 55.3 49.2 3.8 43.5 25.4 27.8 44.9 28.9 79.1 84.9 80.3 107.6 84.3 86.3 79.2 80.5 82.4 85.6 88.0 87.4 51.7 54.5 29.7 14.4 23.5 13.4 40.1 48.5 19.9 30.2 55.7 50.5 122.9 62.9 37.9 69.9 27.1 95.4 19.4 18.2 573.2 43.7 7.3 22.6 29.0 37.6 26.4 18.7 19.1 43.7 37.3 55.7 19.9 26.8 10.1 38.8 26.0 132.6 41.3 6.7 18.4 22.7 44.7 31.2 20.1 14.6 50.7 28.7 23.2 6.5 12.2 67.5 29.9 4.5 11.9 22.1 18.2 68.8 26.7 34.5 65.7 281.7 32.9 21.7 32.9 73.8 49.4 46.7 62.9 37.5 15.6 32.3 25.8 64.2 30.9 34.5 MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 739.7;tongue: 559.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 950.0;Distal tubular cells: 1721.8;Proximal tubular cells: 573.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045119: AB_10960421, HPA055790: AB_2682923" "unprognostic (3.30e-2)" "prognostic favorable (1.45e-4)" "unprognostic (5.24e-3)" "unprognostic (1.68e-1)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (7.61e-2)" "prognostic favorable (1.29e-4)" "unprognostic (3.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (5.64e-2)" "prognostic favorable (4.79e-11)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" "unprognostic (7.48e-2)" "unprognostic (8.45e-2)" 61.7 39.6 105.9 33.4 119.5 57.0 52.8 129.7 153.1 52.4 108.0 97.7 84.8 35.7 44.8 71.5 34.7 41.7 739.7 101.2 127.8 259.9 411.2 44.6 44.3 119.2 123.9 43.4 66.0 141.8 38.1 23.7 119.5 43.5 89.9 57.3 87.7 42.3 319.4 40.9 63.8 38.5 117.1 35.0 96.1 22.2 121.5 48.6 82.9 559.2 44.2 47.4 34.9 132.4 25.6 7.5 31.3 107.7 88.4 49.8 45.2 29.1 47.1 45.1 43.9 38.8 17.9 53.6 50.9 45.4 36.1 24.5 47.0 36.7 31.9 36.1 79.0 27.5 35.4 132.6 36.6 104.9 34.1 40.0 51.0 36.8 26.7 13.7 36.9 80.8 94.2 84.1 28.6 40.5 73.1 193.7 16.1 148.0 35.5 39.1 51.7 134.9 85.4 20.5 96.7 85.7 33.6 145.8 34.0 25.9 34.5 154.3 25.3 25.7 26.8 91.6 30.0 55.8 42.2 46.3 23.5 127.0 42.1 60.7 60.0 90.1 41.7 98.3 39.4 33.1 48.5 45.1 72.2 25.4 44.7 43.3 54.6 40.5 128.5 43.0 69.1 49.8 105.9 119.5 129.7 153.1 101.2 127.8 119.2 123.9 119.5 117.1 121.5 132.4 56.1 118.6 48.0 64.6 51.7 45.6 44.2 83.6 29.0 61.1 74.2 79.1 950.0 187.3 67.6 106.7 10.4 22.0 54.2 219.1 1721.8 89.3 66.8 73.7 50.7 51.7 37.2 72.6 49.0 140.3 78.3 74.1 63.7 93.2 71.0 28.0 47.5 391.0 121.4 48.8 74.7 122.1 166.8 89.6 81.7 10.2 66.5 80.3 129.9 20.6 104.7 199.9 58.7 32.2 108.0 65.2 125.0 89.9 114.5 32.0 162.0 573.6 46.3 66.7 92.1 76.9 80.4 163.2 79.6 67.3 55.8 24.4 58.4 39.9 146.7 53.6 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 MRM2 "FJH1, FTSJ2, RRMJ2" ENSG00000122687 "Mitochondrial rRNA methyltransferase 2" Q9UI43 7 2234195-2242205 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 59.7;Distal tubular cells: 31.3;Extravillous trophoblasts: 37.0;Hofbauer cells: 35.8;Syncytiotrophoblasts: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019826, HPA049622" Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA019826: AB_2670282, HPA049622: AB_2680834" "unprognostic (8.05e-2)" "unprognostic (1.65e-1)" "unprognostic (2.14e-2)" "unprognostic (2.59e-1)" "unprognostic (1.49e-2)" "unprognostic (2.50e-3)" "prognostic unfavorable (5.21e-6)" "unprognostic (8.49e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (9.99e-2)" "unprognostic (8.33e-2)" "unprognostic (1.69e-1)" "unprognostic (2.37e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (1.48e-1)" 9.3 12.8 12.7 12.1 13.3 6.1 13.0 13.5 15.7 9.2 14.2 10.7 10.8 8.2 11.5 11.5 10.8 6.7 14.1 12.5 13.2 12.6 17.3 11.0 17.8 13.9 13.2 11.7 8.0 13.3 6.9 13.7 13.5 10.0 10.8 8.0 10.1 12.0 21.7 11.2 9.1 9.1 14.0 12.8 9.7 10.7 13.4 12.2 8.5 12.6 18.3 10.4 7.9 14.0 62.2 39.9 34.2 25.2 21.3 22.3 24.8 35.3 35.5 45.3 43.9 56.7 29.8 57.5 15.8 27.4 37.5 48.0 49.3 40.0 49.0 22.2 37.9 36.6 37.0 35.0 25.8 54.3 34.5 19.1 34.2 30.4 35.4 19.6 20.2 35.3 59.3 33.0 35.6 73.4 17.1 68.7 94.9 38.6 38.0 34.1 42.5 45.1 31.9 46.4 31.2 44.3 28.9 81.1 34.1 44.8 70.0 81.6 15.1 27.4 64.2 53.8 56.0 29.1 43.4 59.0 31.7 55.9 85.2 17.2 49.1 32.9 28.0 57.1 33.9 52.1 29.9 32.1 71.8 48.8 36.9 32.1 3.7 47.8 48.9 37.8 36.5 40.4 12.7 13.3 13.5 15.7 12.5 13.2 13.9 13.2 13.5 14.0 13.4 14.0 11.3 22.4 19.8 0.0 5.1 0.0 0.0 0.0 0.0 0.0 15.0 19.6 0.0 0.0 8.1 11.0 0.0 59.7 6.6 0.0 31.3 24.1 0.0 7.7 14.3 6.0 0.0 0.0 0.0 19.9 37.0 7.2 0.0 6.7 11.4 15.9 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 11.9 0.0 0.0 0.0 0.0 24.5 0.0 0.0 0.9 0.0 0.0 20.4 9.5 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 37.1 3.6 28.8 0.0 0.0 MRPL12 "MRPL7, MRPL7/L12, RPML12" ENSG00000262814 "Mitochondrial ribosomal protein L12" P52815 17 81703367-81707517 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 303.2;Undifferentiated cells: 364.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022853, HPA023043" Supported Supported Mitochondria NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA022853: AB_1854099, HPA023043: AB_1854100" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (6.59e-2)" "unprognostic (1.66e-2)" "unprognostic (9.52e-2)" "unprognostic (5.97e-2)" "unprognostic (5.97e-3)" "prognostic unfavorable (2.35e-4)" "unprognostic (1.78e-1)" "unprognostic (6.47e-3)" "unprognostic (8.17e-2)" "unprognostic (3.07e-1)" "unprognostic (8.77e-3)" "unprognostic (3.41e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (9.26e-2)" 57.8 73.7 39.4 28.4 39.9 31.0 44.0 46.8 51.9 34.4 50.4 79.7 47.3 39.1 11.0 96.8 35.1 10.9 209.9 39.0 42.2 86.9 184.9 34.9 25.5 40.7 43.1 26.7 60.6 45.9 39.1 19.5 41.0 44.9 37.3 7.3 48.1 21.5 169.7 51.1 51.3 20.6 38.8 53.8 57.9 32.3 46.2 20.1 34.0 148.1 27.7 45.4 46.5 39.4 153.6 256.8 67.5 78.2 50.2 55.0 124.3 117.0 71.3 173.2 128.3 216.5 71.6 236.5 69.2 77.5 116.7 127.1 87.6 150.7 87.6 55.9 438.3 181.1 140.2 246.5 74.0 200.5 90.9 63.4 108.5 119.4 132.4 55.4 146.1 115.6 179.4 75.6 87.1 194.2 171.6 295.9 106.0 165.9 330.6 160.7 109.5 176.4 129.8 126.1 171.4 220.7 86.1 366.1 199.8 69.1 186.2 180.5 76.7 131.0 155.8 103.4 241.2 146.2 54.3 137.0 89.3 143.0 100.6 17.7 63.1 9.0 37.9 84.8 52.6 66.2 37.8 42.6 93.7 62.1 39.2 36.0 6.9 43.5 49.8 77.0 35.8 48.9 39.4 39.9 46.8 51.9 39.0 42.2 40.7 43.1 41.0 38.8 46.2 39.4 43.0 19.2 12.8 4.9 42.2 53.3 83.7 101.7 8.6 17.1 67.2 85.0 88.7 84.4 47.6 46.0 4.2 172.4 29.1 303.2 219.2 113.0 38.9 40.6 39.8 47.8 104.0 40.4 4.5 118.5 187.2 38.9 28.5 33.6 30.5 75.7 39.7 223.4 167.0 23.5 6.0 257.7 44.7 62.2 34.5 127.2 39.4 36.8 58.7 1.9 59.7 29.7 45.3 3.0 4.6 126.5 126.9 32.7 24.4 137.1 196.2 258.5 35.0 17.3 32.9 30.8 65.1 46.5 56.9 30.1 60.5 112.5 25.2 126.0 364.0 109.8 MRPL16 "FLJ20484, PNAS-111" ENSG00000166902 "Mitochondrial ribosomal protein L16" Q9NX20 11 59806140-59810778 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054133 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA054133: AB_2682394" "prognostic favorable (1.04e-4)" "unprognostic (1.13e-1)" "unprognostic (3.45e-3)" "unprognostic (5.88e-2)" "unprognostic (2.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.20e-1)" "unprognostic (2.40e-3)" "unprognostic (1.50e-3)" "unprognostic (2.67e-2)" "unprognostic (2.87e-3)" "unprognostic (3.01e-2)" "unprognostic (1.23e-1)" "unprognostic (6.38e-2)" "unprognostic (2.01e-2)" 35.2 61.4 44.1 29.6 44.7 57.0 34.6 45.6 54.7 30.4 45.4 49.7 42.1 32.7 23.1 33.7 29.0 20.6 85.7 44.2 45.3 51.2 78.3 25.6 44.3 43.4 44.0 31.5 38.6 56.1 23.0 29.8 43.8 25.3 48.3 21.4 43.2 28.8 85.8 24.6 34.7 36.3 44.5 41.6 44.3 34.1 45.3 50.7 20.7 103.5 46.0 29.4 25.7 44.8 76.3 75.4 53.4 50.1 74.9 59.1 48.0 52.1 68.9 93.9 80.1 75.1 79.5 174.0 87.0 68.2 50.3 72.8 178.0 96.9 84.0 58.9 89.5 92.7 69.9 89.5 57.8 139.4 55.1 71.1 52.4 78.8 56.4 54.5 92.4 112.6 278.4 51.2 70.9 150.6 97.8 224.1 84.1 89.8 124.2 85.4 78.6 91.1 137.2 103.3 50.2 34.9 83.4 83.8 134.3 49.4 100.1 132.0 46.3 36.9 50.7 77.4 63.7 57.9 69.8 240.7 44.9 88.1 40.8 80.8 95.1 72.9 87.4 118.1 91.0 118.7 96.5 91.5 116.1 121.2 102.8 91.4 18.1 116.8 94.5 166.9 108.2 149.7 44.1 44.7 45.6 54.7 44.2 45.3 43.4 44.0 43.8 44.5 45.3 44.8 44.3 48.1 31.4 10.4 43.6 31.9 19.7 87.9 34.1 9.9 29.4 47.0 146.1 31.5 42.6 42.3 12.5 94.2 45.9 35.5 248.4 47.9 18.0 28.5 41.5 41.0 34.1 64.8 9.0 53.4 74.1 46.7 46.9 28.5 61.4 104.6 35.7 73.6 75.3 8.4 10.9 67.7 46.8 45.6 24.4 11.8 39.7 34.5 44.4 10.3 54.4 45.4 42.2 9.5 8.0 43.0 42.2 37.6 66.0 19.4 65.6 125.2 44.0 17.0 72.3 34.1 53.1 54.8 46.5 64.4 36.8 28.5 34.9 120.3 82.2 22.3 MRPL2 "CGI-22, MRP-L14, RPML14" ENSG00000112651 "Mitochondrial ribosomal protein L2" Q5T653 6 43054029-43059438 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007455, HPA064814" Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA007455: AB_1079410, HPA064814: AB_2685358" "unprognostic (2.31e-1)" "unprognostic (1.49e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.17e-1)" "prognostic favorable (6.01e-4)" "unprognostic (3.07e-1)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "unprognostic (6.42e-2)" "unprognostic (2.33e-2)" "unprognostic (3.13e-1)" "unprognostic (2.78e-1)" 26.5 32.4 27.9 12.6 28.8 20.0 26.0 31.0 37.6 23.2 27.9 27.5 25.6 23.5 13.7 24.6 22.2 10.1 48.2 28.3 31.7 33.7 51.2 18.6 13.4 29.8 28.9 24.5 27.1 29.6 29.5 13.3 30.1 22.0 16.8 10.9 22.6 17.6 75.1 25.1 20.3 12.0 27.4 19.9 23.6 19.7 29.0 17.7 26.7 56.7 14.4 22.6 21.4 28.9 47.9 43.1 20.3 39.3 28.4 20.7 38.9 20.4 24.8 47.3 41.3 109.0 15.4 61.8 42.3 24.6 36.2 49.9 50.5 48.7 27.8 30.4 90.9 46.8 34.9 109.5 57.2 43.5 21.0 27.6 51.4 52.5 82.8 22.6 32.6 68.7 84.6 36.6 23.6 84.0 48.1 127.1 22.7 175.7 49.5 59.0 25.1 77.3 38.2 26.3 51.3 27.4 18.2 39.4 73.4 18.6 41.4 73.9 27.3 27.6 40.0 35.7 58.7 47.7 44.9 115.2 21.5 65.2 27.8 17.5 37.8 30.2 28.4 40.9 36.5 46.5 31.8 33.6 54.3 48.6 32.7 32.3 9.8 38.5 33.7 56.1 39.2 31.3 27.9 28.8 31.0 37.6 28.3 31.7 29.8 28.9 30.1 27.4 29.0 28.9 36.8 22.4 18.6 5.5 27.5 24.3 32.0 86.5 19.4 22.7 25.9 30.0 37.5 38.6 48.9 60.7 27.1 74.0 21.3 43.1 185.9 59.1 94.0 30.6 34.1 32.1 30.6 35.3 5.3 53.7 53.1 31.1 30.1 32.5 28.5 43.1 33.2 75.9 49.3 5.0 5.8 44.2 69.2 23.7 26.6 37.0 55.0 22.9 53.4 2.8 41.3 44.7 43.3 2.0 5.5 44.2 51.3 51.6 35.6 31.6 77.6 159.4 40.4 23.4 26.3 32.5 82.7 53.1 41.7 35.7 27.1 63.5 27.2 59.0 65.7 28.7 MRPL20 FLJ10024 ENSG00000242485 "Mitochondrial ribosomal protein L20" Q9BYC9 1 1401909-1407293 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047074 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047074: AB_10964064" "unprognostic (4.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-2)" "unprognostic (5.79e-2)" "unprognostic (3.71e-1)" "unprognostic (2.66e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (2.80e-2)" "unprognostic (2.33e-1)" "unprognostic (4.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.25e-1)" "unprognostic (4.34e-2)" "unprognostic (1.64e-1)" 111.5 120.2 144.2 81.8 156.1 72.1 110.0 144.3 178.5 86.5 148.7 126.7 83.6 89.7 135.0 117.2 90.2 68.5 189.8 146.7 154.3 140.9 152.7 86.7 100.4 152.4 154.1 84.2 136.6 100.6 117.3 68.6 147.2 110.9 86.9 59.6 131.9 90.3 277.2 97.7 91.3 75.4 158.1 100.2 116.8 60.5 168.6 71.8 102.3 160.9 102.5 107.6 87.6 158.1 216.1 204.2 149.7 152.8 113.4 122.7 110.6 188.3 143.8 240.7 171.1 244.9 255.4 228.5 256.8 162.9 111.4 133.8 247.6 203.8 185.9 199.0 350.3 247.0 369.0 244.8 156.5 367.3 152.7 143.9 76.8 184.8 196.4 138.4 181.1 213.8 254.6 131.8 204.8 216.3 285.2 279.2 155.8 249.6 409.1 186.0 138.3 291.3 189.9 142.8 265.4 218.5 179.2 369.9 288.7 124.7 158.8 268.0 155.2 144.9 170.0 219.6 236.2 200.6 313.5 450.5 224.2 296.4 103.7 124.6 191.2 146.5 164.8 190.1 183.7 189.3 181.9 163.3 198.2 177.2 204.1 199.0 89.2 163.1 150.8 289.2 175.0 219.6 144.2 156.1 144.3 178.5 146.7 154.3 152.4 154.1 147.2 158.1 168.6 158.1 97.5 67.3 115.5 19.9 120.3 130.3 134.8 206.8 99.0 77.8 153.0 171.4 255.2 145.8 166.0 161.8 35.5 234.5 129.2 138.6 530.2 232.6 39.3 153.1 121.8 118.4 138.2 152.7 13.7 325.9 265.0 113.6 87.7 126.3 106.2 92.7 131.0 384.0 220.6 50.5 13.8 185.5 177.0 139.7 111.0 30.7 107.8 117.9 138.7 11.2 200.8 279.3 183.4 9.5 20.8 261.8 167.4 110.9 163.3 254.8 194.1 543.9 146.9 107.7 65.7 121.8 135.7 131.7 202.7 179.9 157.7 226.2 109.2 121.9 216.1 170.2 MRPL21 ENSG00000197345 "Mitochondrial ribosomal protein L21" Q7Z2W9 11 68891276-68903835 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051657 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA051657: AB_2681565" "unprognostic (1.80e-1)" "unprognostic (6.09e-2)" "unprognostic (4.80e-2)" "unprognostic (8.96e-3)" "unprognostic (9.25e-3)" "prognostic unfavorable (5.97e-4)" "unprognostic (3.23e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.84e-2)" "unprognostic (7.36e-2)" "unprognostic (1.26e-2)" "unprognostic (3.73e-2)" "unprognostic (1.72e-1)" "unprognostic (4.36e-2)" "unprognostic (3.12e-1)" 43.5 44.4 56.0 34.0 57.3 60.5 52.5 62.8 71.9 45.3 57.7 67.1 38.7 50.4 48.4 58.4 45.2 27.1 120.2 57.6 59.5 68.0 66.1 31.5 43.8 59.5 57.4 48.6 53.6 56.3 44.7 33.1 59.6 44.1 42.5 29.7 99.5 39.1 131.0 50.4 46.0 35.1 56.9 37.0 53.0 47.0 57.9 37.2 44.7 109.1 42.9 49.8 44.9 56.9 105.2 145.6 86.0 82.3 59.1 63.5 101.4 71.8 77.2 132.8 90.4 297.3 132.7 163.5 157.2 78.0 122.0 129.9 143.8 138.6 102.8 109.7 112.6 114.4 102.4 181.0 116.6 201.4 83.4 95.0 69.4 134.1 156.0 64.7 93.7 115.1 229.2 119.4 80.7 196.7 95.5 210.5 78.0 307.6 210.3 135.2 102.9 253.0 134.0 120.8 139.3 111.3 91.1 181.6 302.7 68.7 188.7 115.4 79.3 90.6 90.6 201.3 135.5 88.9 149.5 232.3 120.6 120.4 125.7 79.6 113.0 61.6 72.4 122.8 77.1 162.2 94.5 78.8 124.2 105.8 89.3 74.1 32.1 93.3 114.2 92.0 113.2 114.0 56.0 57.3 62.8 71.9 57.6 59.5 59.5 57.4 59.6 56.9 57.9 56.9 38.9 35.3 38.7 5.5 47.4 50.2 76.8 145.1 68.9 36.3 56.5 65.4 179.8 67.2 82.0 80.9 8.4 122.8 34.6 127.7 299.3 106.7 176.9 72.2 59.8 50.4 61.7 56.0 5.6 105.3 114.8 53.9 42.8 63.0 65.2 31.8 40.7 115.9 110.4 11.8 6.4 115.6 85.5 56.3 41.3 227.3 74.9 47.0 78.2 1.0 69.8 69.0 34.0 2.0 5.1 86.3 93.0 72.2 63.8 79.6 150.6 272.9 72.8 51.4 26.3 59.3 85.8 86.6 60.5 83.2 51.9 81.3 44.2 55.0 141.6 75.0 MRPL24 MRP-L18 ENSG00000143314 "Mitochondrial ribosomal protein L24" Q96A35 1 156737303-156741590 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 213.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030295, HPA054323" Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA030295: AB_10600932, HPA054323: AB_2732583" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (2.26e-2)" "unprognostic (1.47e-2)" "unprognostic (2.83e-1)" "unprognostic (3.69e-2)" "unprognostic (1.71e-2)" "unprognostic (3.11e-1)" "unprognostic (1.63e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-3)" "unprognostic (2.73e-2)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.47e-1)" "unprognostic (8.75e-2)" "unprognostic (3.74e-1)" "unprognostic (1.94e-1)" 78.1 93.8 75.4 43.0 78.6 24.0 69.8 79.6 81.2 51.3 71.4 70.3 40.7 58.3 94.6 55.4 72.7 33.8 108.4 74.0 77.4 77.9 130.6 37.2 46.1 77.7 75.9 65.6 100.2 86.1 41.1 41.5 78.9 49.1 67.8 26.9 71.2 65.7 149.6 50.7 41.8 76.6 76.3 43.1 62.0 37.4 77.3 42.8 52.5 143.0 57.1 67.1 48.0 82.0 146.0 238.2 50.2 62.0 157.0 167.6 98.7 115.6 72.2 153.6 86.5 96.5 149.7 112.1 189.3 153.2 74.9 141.3 121.8 238.9 153.3 136.6 152.7 104.9 164.9 94.7 176.8 115.9 70.8 156.5 205.0 232.3 243.4 92.9 136.4 136.5 105.4 129.2 155.1 259.9 130.6 115.2 93.0 495.3 289.8 83.7 134.7 229.1 192.3 105.2 64.0 129.4 70.3 391.6 192.5 95.4 233.9 130.6 104.1 141.8 108.9 141.1 200.3 144.1 131.5 116.1 133.8 135.5 143.8 38.3 62.3 11.2 63.1 77.4 95.8 87.2 82.3 77.5 81.5 86.9 81.4 86.0 3.3 97.1 75.0 68.4 72.0 93.5 75.4 78.6 79.6 81.2 74.0 77.4 77.7 75.9 78.9 76.3 77.3 82.0 26.3 32.1 31.6 3.9 33.7 30.5 67.0 65.4 39.3 13.8 46.8 51.3 157.0 80.1 49.1 42.3 4.2 92.4 27.5 28.0 154.6 53.5 26.7 31.5 45.0 40.9 36.0 22.9 5.7 76.6 87.9 51.0 36.7 37.0 60.3 30.9 35.7 133.6 79.7 15.2 6.3 45.7 36.7 27.3 29.4 13.4 55.9 29.1 74.7 1.9 47.9 22.2 36.0 4.5 10.0 40.2 35.3 53.0 43.4 53.7 44.9 213.2 41.7 13.7 32.9 53.0 62.0 46.8 48.5 66.1 36.7 40.8 28.7 59.7 69.5 62.1 MRPL27 ENSG00000108826 "Mitochondrial ribosomal protein L27" Q9P0M9 17 50367857-50373207 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 377.6;Proximal tubular cells: 409.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021416 Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA021416: AB_1854103" "unprognostic (2.09e-1)" "unprognostic (2.27e-2)" "unprognostic (4.66e-2)" "unprognostic (8.23e-2)" "unprognostic (2.10e-2)" "unprognostic (2.99e-2)" "unprognostic (7.03e-2)" "unprognostic (1.42e-1)" "unprognostic (8.79e-2)" "unprognostic (1.96e-2)" "unprognostic (2.43e-2)" "unprognostic (4.27e-2)" "unprognostic (1.65e-1)" "unprognostic (1.14e-1)" "unprognostic (7.61e-2)" "unprognostic (3.14e-2)" "unprognostic (7.76e-3)" 51.4 92.4 103.3 36.8 105.9 35.7 55.2 108.9 129.4 48.5 105.6 73.5 53.8 46.2 115.5 72.8 44.1 29.9 106.5 102.6 106.3 90.7 109.4 37.3 44.8 106.6 105.7 45.9 59.2 75.5 52.3 57.2 107.4 58.2 84.4 32.9 50.3 45.0 141.1 60.2 52.2 50.9 106.1 45.6 91.2 42.4 109.0 61.2 49.7 140.5 64.7 58.0 51.0 108.0 160.2 231.3 105.5 69.8 66.5 98.9 154.3 117.1 111.8 216.9 195.5 535.5 82.6 139.3 143.5 146.0 168.0 97.3 160.9 177.8 176.2 142.2 273.0 145.5 199.8 393.1 123.4 121.9 125.3 114.3 242.9 172.8 103.0 94.7 149.0 75.8 157.4 81.0 153.4 304.2 135.6 154.0 76.4 279.4 252.4 74.4 143.6 114.5 187.8 213.6 108.1 130.4 55.0 71.3 104.9 140.0 171.2 100.6 89.8 145.0 110.5 109.4 192.1 97.6 120.5 127.8 97.6 101.7 76.4 212.7 175.6 124.6 99.3 209.2 82.9 211.4 117.2 104.5 177.1 186.4 113.9 99.0 27.9 108.7 153.6 193.5 159.0 179.3 103.3 105.9 108.9 129.4 102.6 106.3 106.6 105.7 107.4 106.1 109.0 108.0 33.6 38.5 43.7 12.7 50.7 60.0 97.2 220.9 56.9 35.5 50.1 65.8 180.5 88.6 111.2 90.1 14.6 240.7 36.8 179.7 377.6 136.5 27.7 60.1 61.7 58.1 103.0 55.3 10.0 146.5 181.9 70.6 99.9 63.9 29.7 52.1 57.8 221.4 150.6 15.2 12.9 193.3 132.2 52.5 33.9 31.1 83.0 52.0 69.4 12.2 88.8 72.5 42.2 15.6 14.5 153.8 139.0 83.8 58.2 83.9 199.5 409.5 73.5 42.1 72.3 57.1 85.8 88.7 74.6 81.6 75.4 273.4 36.4 97.5 155.3 102.6 MRPL28 "MAAT1, p15" ENSG00000086504 "Mitochondrial ribosomal protein L28" Q13084 16 366969-371289 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030594, CAB033542, HPA055589" Supported Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "CAB033542: AB_2145899, HPA030594: AB_10601136, HPA055589: AB_2682855" "unprognostic (2.39e-1)" "unprognostic (7.39e-3)" "unprognostic (1.53e-1)" "unprognostic (1.26e-1)" "unprognostic (2.15e-2)" "unprognostic (9.92e-2)" "unprognostic (2.92e-1)" "unprognostic (3.45e-3)" "unprognostic (6.76e-2)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (4.36e-1)" "unprognostic (2.60e-1)" "unprognostic (6.56e-2)" 43.3 63.2 43.2 25.8 46.6 43.7 43.6 41.6 55.9 40.8 39.9 48.9 31.4 47.0 20.6 58.0 39.4 23.3 101.0 46.9 42.7 74.9 79.9 38.7 30.4 41.2 41.7 36.4 32.2 46.6 44.0 21.1 42.5 45.3 18.1 20.4 37.9 23.8 87.6 45.9 43.0 25.8 41.2 52.2 43.8 85.2 42.2 36.8 44.2 59.3 27.1 43.1 42.3 43.9 72.8 135.8 68.3 82.9 37.9 48.6 90.1 82.6 107.3 147.2 143.2 175.4 95.9 105.5 88.6 85.0 75.3 87.6 107.8 172.6 78.2 95.4 211.8 78.7 110.0 149.2 123.9 98.1 96.1 73.8 84.6 136.3 110.5 69.0 109.5 99.5 143.8 75.6 93.0 249.0 152.9 98.2 109.1 72.3 82.5 181.7 85.2 149.1 121.4 41.3 115.2 102.4 102.5 100.3 84.6 66.4 131.1 92.4 85.5 86.0 118.6 70.8 92.4 111.1 100.3 143.0 60.0 68.4 140.8 95.4 105.7 122.1 71.0 107.2 59.1 93.3 62.0 68.9 96.6 105.0 43.0 54.7 120.5 79.3 115.1 119.0 125.8 97.9 43.2 46.6 41.6 55.9 46.9 42.7 41.2 41.7 42.5 41.2 42.2 43.9 44.2 38.5 34.1 8.5 43.6 34.7 50.4 134.5 25.6 34.8 35.6 36.4 55.4 40.0 69.0 69.9 8.4 87.0 46.8 70.2 193.7 112.5 97.7 35.3 30.0 44.9 64.1 51.3 5.8 111.9 108.0 41.2 37.2 31.2 26.6 57.2 47.2 66.6 99.7 28.6 5.0 54.6 77.3 66.5 36.1 232.6 38.2 47.8 71.2 2.8 136.1 56.1 45.3 3.0 5.4 107.0 76.5 38.4 47.2 46.7 106.3 180.0 55.4 42.5 39.5 31.0 61.9 122.2 50.5 38.9 32.4 45.8 37.1 86.6 65.8 52.9 MRPL34 "L34mt, MGC24974, MGC2633" ENSG00000130312 "Mitochondrial ribosomal protein L34" Q9BQ48 19 17292609-17306843 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 403.0;Proximal tubular cells: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049276 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA049276: AB_2680697" "unprognostic (1.21e-2)" "unprognostic (3.22e-2)" "unprognostic (4.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (4.27e-2)" "unprognostic (1.46e-1)" "unprognostic (4.93e-2)" "unprognostic (1.29e-1)" "unprognostic (5.45e-2)" "prognostic favorable (4.87e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.29e-6)" "unprognostic (2.44e-1)" "unprognostic (2.42e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-2)" 69.6 115.4 64.0 27.5 67.0 26.2 64.7 69.2 72.2 51.4 96.7 99.7 71.5 58.7 23.5 62.8 45.6 17.6 178.2 63.4 69.5 126.0 195.0 47.1 28.6 64.3 64.1 40.9 69.5 91.8 74.1 20.3 64.6 55.3 29.8 31.6 65.3 40.2 210.5 60.6 75.8 18.3 64.1 55.8 87.7 93.6 70.7 38.0 61.5 139.6 21.8 64.0 50.6 66.0 91.9 55.3 35.4 45.4 88.2 48.7 132.1 45.4 47.7 36.6 44.8 53.6 64.2 115.2 126.7 25.2 50.7 73.6 57.1 53.5 25.9 171.3 198.5 81.4 87.2 119.2 78.7 89.2 103.9 56.6 71.2 38.0 52.1 38.9 57.8 95.5 119.6 136.4 35.7 86.7 113.4 187.4 97.6 147.2 293.8 97.9 52.0 160.9 107.9 68.6 84.1 136.7 42.6 67.2 105.9 37.0 58.7 74.3 49.0 52.7 32.8 151.6 87.4 186.5 305.3 129.0 65.4 161.7 49.1 169.6 162.3 159.5 172.4 177.0 192.5 204.0 203.5 177.3 178.1 211.0 197.5 172.2 52.3 141.7 107.0 233.6 210.8 276.7 64.0 67.0 69.2 72.2 63.4 69.5 64.3 64.1 64.6 64.1 70.7 66.0 64.4 35.3 41.4 13.7 51.7 60.7 33.0 128.5 74.0 50.2 81.7 108.2 153.4 91.5 64.6 82.8 20.9 118.5 94.1 138.9 403.0 88.5 57.6 48.1 46.7 54.2 68.3 45.5 16.1 68.8 112.1 55.6 60.1 45.4 39.3 37.1 59.6 290.3 172.4 42.1 16.7 125.4 134.3 70.1 55.9 31.9 82.0 61.4 81.8 6.5 90.0 45.0 97.9 6.0 12.8 64.7 99.1 91.7 80.3 45.7 219.5 414.8 42.3 49.7 72.3 48.1 69.7 233.1 14.9 93.2 72.0 78.3 62.0 109.5 130.6 36.7 MRPL36 "BRIP1, L36mt, MRP-L36, PRPL36, RPMJ" ENSG00000171421 "Mitochondrial ribosomal protein L36" Q9P0J6 5 1798385-1801366 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 472.3;Late spermatids: 471.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047238 Approved Supported "Nuclear bodies,Mitochondria" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear bodies, Mitochondria" "HPA047238: AB_10965331" "unprognostic (2.23e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-2)" "unprognostic (7.83e-3)" "unprognostic (2.03e-2)" "unprognostic (2.01e-2)" "unprognostic (1.09e-3)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (1.37e-2)" "unprognostic (5.39e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (8.53e-2)" "unprognostic (9.83e-2)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" 46.2 60.4 35.6 24.7 36.9 19.2 42.1 40.9 44.2 31.5 36.3 49.6 27.9 38.6 26.3 51.1 32.3 22.0 77.3 36.6 38.4 70.4 76.1 28.6 30.1 37.8 36.9 35.1 44.4 34.6 29.1 21.8 38.4 44.0 20.0 22.6 36.5 21.6 140.2 39.3 33.7 26.9 38.3 34.3 44.9 97.4 38.3 29.1 27.4 86.1 25.9 38.8 34.2 38.3 93.3 134.9 61.7 116.9 111.3 91.2 80.9 79.4 69.4 92.7 88.2 98.4 73.4 124.2 140.2 85.7 136.1 99.1 139.9 130.9 66.8 136.1 155.8 60.2 285.1 158.4 142.0 78.9 45.5 80.9 98.9 103.6 133.4 80.8 91.1 72.3 93.4 77.9 133.6 169.4 93.2 177.5 60.1 102.2 164.0 73.8 46.0 149.6 84.6 74.9 68.5 46.8 172.6 133.1 89.8 56.3 78.2 84.5 55.5 79.9 87.1 54.7 89.4 74.0 100.3 167.4 100.4 144.5 111.3 88.4 103.2 68.6 90.6 104.8 109.6 132.6 101.5 111.1 127.3 103.3 89.1 106.3 29.7 101.7 92.9 476.0 143.0 142.0 35.6 36.9 40.9 44.2 36.6 38.4 37.8 36.9 38.4 38.3 38.3 38.3 52.6 32.1 29.0 6.8 37.6 106.0 108.8 150.2 89.4 23.0 61.5 93.2 163.1 50.1 83.6 58.8 6.2 93.4 66.0 47.3 307.2 84.1 472.3 45.4 63.9 63.7 26.4 50.9 7.9 75.0 74.0 62.7 35.2 33.1 27.9 46.2 35.7 118.2 88.2 15.2 7.9 53.8 107.8 43.0 52.4 471.3 74.9 32.0 60.5 2.8 62.5 76.0 70.0 7.1 9.6 92.1 58.7 59.8 45.6 148.8 79.2 199.6 63.2 31.2 65.7 51.1 68.6 188.6 76.2 92.4 124.9 87.4 37.3 79.8 65.7 112.6 MRPL38 "HSPC262, MGC4810, MRP-L3, RPML3" ENSG00000204316 "Mitochondrial ribosomal protein L38" Q96DV4 17 75898644-75905093 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 34.7;Gastric mucus-secreting cells: 35.2;Plasma cells: 60.1;Squamous epithelial cells: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023054, HPA023135" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA023054: AB_1854109, HPA023135: AB_1854110" "unprognostic (1.17e-1)" "unprognostic (3.77e-3)" "unprognostic (1.83e-1)" "unprognostic (3.68e-3)" "unprognostic (2.47e-2)" "unprognostic (1.50e-2)" "unprognostic (4.44e-2)" "unprognostic (1.61e-1)" "unprognostic (7.59e-2)" "unprognostic (5.24e-2)" "prognostic favorable (4.23e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (5.58e-4)" "unprognostic (3.06e-2)" "unprognostic (2.40e-1)" "unprognostic (3.72e-1)" "prognostic favorable (9.21e-5)" 23.3 34.7 37.5 16.3 37.4 21.9 22.8 39.7 48.9 20.2 37.8 31.1 26.8 24.0 14.4 30.0 30.6 14.6 51.5 37.7 38.2 31.3 46.8 18.2 23.8 39.4 37.6 22.3 36.8 28.7 19.6 17.3 39.8 22.6 19.2 6.7 36.6 26.2 103.2 26.9 21.9 20.3 38.1 22.5 28.6 25.3 40.4 23.8 20.6 84.7 22.4 25.9 21.0 38.6 82.2 114.2 28.3 39.2 32.5 26.5 86.5 26.4 44.5 96.3 69.5 134.4 49.3 72.7 31.2 45.9 55.1 59.1 79.2 71.1 27.3 24.0 130.5 51.0 39.9 133.7 72.0 69.5 48.6 36.6 77.3 66.8 52.4 29.3 92.6 89.7 64.6 45.6 36.6 163.0 92.9 75.1 33.6 101.8 97.2 69.1 74.7 92.3 76.3 51.0 48.6 51.4 45.3 121.3 104.5 26.1 112.4 74.4 26.3 45.8 67.2 38.6 75.4 51.1 32.1 24.7 50.0 57.1 41.3 24.4 74.1 37.9 84.2 80.8 84.0 101.8 86.0 79.1 106.7 113.7 84.8 81.7 7.0 95.7 69.1 78.1 93.7 83.6 37.5 37.4 39.7 48.9 37.7 38.2 39.4 37.6 39.8 38.1 40.4 38.6 1.7 19.2 7.3 14.7 19.3 1.5 0.8 2.7 34.7 1.0 2.4 1.1 2.3 0.0 5.5 3.7 0.0 5.1 6.6 11.4 3.9 23.8 1.1 2.2 1.8 4.7 10.3 20.2 11.9 21.4 3.7 8.1 35.2 1.8 3.8 1.0 2.5 2.4 3.3 1.7 13.2 13.9 2.0 0.8 1.9 1.9 3.1 6.1 7.2 5.6 14.2 0.9 5.2 7.5 15.7 19.2 17.9 3.0 60.1 1.3 16.3 5.6 9.8 2.9 0.0 0.9 8.3 1.9 1.9 46.2 1.4 3.4 13.6 1.2 20.9 0.8 MRPL40 "MRP-L22, NLVCF" ENSG00000185608 "Mitochondrial ribosomal protein L40" Q9NQ50 22 19432545-19436075 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006181 Uncertain Supported Nucleoli,Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "HPA006181: AB_1079411" "unprognostic (4.12e-2)" "prognostic favorable (7.57e-4)" "unprognostic (2.64e-2)" "unprognostic (1.29e-1)" "unprognostic (5.76e-2)" "unprognostic (4.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" "unprognostic (4.08e-2)" "unprognostic (1.19e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (2.67e-2)" "unprognostic (1.75e-1)" "unprognostic (8.07e-2)" "unprognostic (2.29e-1)" "unprognostic (3.14e-2)" 39.4 54.4 59.9 26.1 61.6 28.3 47.6 63.9 79.7 50.0 60.3 33.6 26.1 31.3 77.4 35.6 54.8 31.5 100.7 59.0 62.3 69.1 118.8 28.9 35.5 62.5 60.6 44.5 57.1 85.0 11.2 30.7 62.5 46.4 35.9 35.0 72.1 43.0 135.8 29.2 24.7 32.6 63.6 27.1 33.8 31.4 61.7 29.7 79.0 142.0 40.9 36.4 7.0 65.0 84.8 83.8 26.9 64.0 111.5 98.8 45.4 62.1 95.6 116.9 133.6 105.5 49.0 73.2 71.0 93.7 67.8 82.9 118.8 141.2 122.6 69.8 129.7 72.8 76.0 184.4 158.1 117.7 46.1 102.3 123.6 101.1 179.8 77.3 95.6 35.0 265.8 91.2 127.5 106.9 44.9 77.6 22.7 190.2 100.3 49.7 110.6 44.2 135.9 67.9 45.6 48.3 100.7 94.0 159.7 60.2 80.2 52.9 60.6 118.6 127.3 41.6 64.0 78.1 115.7 147.6 79.2 71.6 99.5 45.1 88.3 76.6 71.7 108.9 82.7 162.7 72.4 74.6 100.1 155.6 85.9 75.6 10.4 90.5 90.2 106.5 91.9 103.5 59.9 61.6 63.9 79.7 59.0 62.3 62.5 60.6 62.5 63.6 61.7 65.0 43.3 44.8 35.3 8.8 53.8 40.4 73.3 181.9 52.3 31.0 59.4 85.9 86.1 71.4 106.6 47.8 12.5 129.6 42.9 35.2 260.3 83.8 114.9 104.4 61.9 40.3 34.9 27.1 3.6 97.9 128.9 55.9 32.1 46.1 33.7 44.2 40.0 146.3 135.6 21.9 5.8 47.8 91.6 43.6 40.0 152.4 72.4 42.9 85.4 4.7 73.9 120.4 37.0 3.5 12.0 73.9 48.6 72.2 92.6 53.6 89.8 254.9 163.5 50.3 46.0 53.9 74.3 82.9 72.1 64.8 38.5 62.9 35.1 103.8 49.3 52.2 MRPL41 "BMRP, MRP-L27, MRPL27, PIG3, RPML27" ENSG00000182154 "Mitochondrial ribosomal protein L41" Q8IXM3 9 137551879-137552555 "Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 340.5;skeletal muscle: 407.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 909.5;Distal tubular cells: 972.4;Hepatocytes: 856.2;Late spermatids: 839.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 503.2;PC-3: 471.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024550, HPA027160" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA024550: AB_1854112, HPA027160: AB_1854113" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (6.92e-2)" "unprognostic (1.22e-3)" "unprognostic (5.86e-3)" "unprognostic (8.04e-2)" "unprognostic (2.05e-1)" "unprognostic (1.60e-1)" "unprognostic (1.47e-1)" "unprognostic (1.14e-1)" "unprognostic (4.83e-3)" "unprognostic (3.24e-2)" "unprognostic (2.06e-3)" "unprognostic (3.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" 83.7 74.7 222.0 22.9 206.1 26.1 57.4 203.8 340.5 53.9 169.2 66.4 45.4 45.9 8.4 42.4 46.6 14.8 325.4 210.3 190.6 79.8 157.8 42.1 24.6 209.0 190.7 61.1 44.8 42.2 55.1 12.2 187.9 113.0 17.4 9.9 69.6 26.2 407.5 58.6 56.8 12.2 183.4 54.2 79.1 40.3 227.1 16.1 44.9 129.4 13.1 59.4 45.4 188.9 93.7 165.9 25.5 61.9 40.7 35.5 122.1 112.8 33.1 59.1 47.4 122.6 49.6 71.0 148.4 31.5 78.0 186.5 37.4 60.0 6.4 97.9 208.6 62.0 91.9 193.6 92.8 101.1 211.4 67.3 85.4 51.5 18.2 23.4 55.4 58.7 147.8 26.8 32.6 503.2 33.7 337.6 94.6 118.0 471.6 40.1 44.0 95.9 50.5 67.7 85.7 88.6 78.0 138.6 194.5 15.2 124.0 91.5 95.4 93.1 121.3 162.9 153.4 78.4 146.2 133.7 101.8 104.4 70.9 425.2 305.5 251.8 225.6 272.9 211.5 313.8 235.0 257.0 260.3 249.7 221.0 206.2 38.3 180.8 254.2 422.6 332.2 350.3 222.0 206.1 203.8 340.5 210.3 190.6 209.0 190.7 187.9 183.4 227.1 188.9 99.0 28.9 33.6 59.7 90.7 140.1 138.3 239.3 121.3 52.4 193.9 221.5 909.5 178.7 121.1 263.0 10.4 115.9 89.7 670.5 972.4 157.8 299.6 165.2 136.0 103.1 268.5 66.0 30.6 192.1 147.7 127.1 192.7 136.7 54.0 85.4 102.1 856.2 244.8 28.6 47.7 332.9 229.9 122.7 115.4 839.0 121.8 106.0 224.1 15.9 162.1 102.7 95.8 8.0 31.1 222.8 446.5 104.6 146.9 223.1 458.4 657.6 134.9 47.5 111.7 66.8 143.8 112.6 79.7 175.6 166.1 82.2 112.8 249.9 348.8 176.8 MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Proximal tubular cells: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cell Junctions" "HPA050166: AB_2681039, HPA076046: " "unprognostic (1.42e-1)" "unprognostic (6.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-2)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (4.64e-3)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "prognostic favorable (2.09e-6)" "unprognostic (7.73e-2)" "unprognostic (9.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.63e-1)" 25.1 51.5 20.3 12.9 21.7 11.3 22.7 23.7 25.4 14.6 22.0 24.2 20.0 17.1 18.2 26.4 17.1 13.0 76.1 20.8 23.6 34.7 70.9 12.7 20.9 23.1 22.1 17.2 16.2 24.6 16.2 19.6 23.6 14.9 23.6 16.8 17.1 15.2 73.3 17.9 19.7 18.4 21.7 19.1 24.8 28.1 22.7 18.9 17.2 84.6 20.3 20.7 16.2 22.6 27.8 87.2 27.2 29.8 38.0 28.6 51.5 38.6 35.5 56.9 50.4 108.6 59.3 64.9 38.6 34.9 51.0 65.9 107.4 47.4 44.8 26.3 86.4 53.6 61.5 114.3 24.6 54.2 40.4 32.7 56.6 42.8 28.7 29.0 50.2 63.2 60.7 26.6 42.7 59.6 44.2 68.4 43.5 50.5 52.9 51.9 37.9 49.2 44.5 88.2 42.1 26.5 36.6 57.7 81.8 44.6 64.8 65.7 31.3 44.0 41.9 23.3 56.4 24.2 55.7 53.0 48.5 58.1 34.2 27.1 45.5 33.7 60.0 60.5 69.6 78.8 63.3 58.7 58.7 69.5 69.5 61.6 7.9 62.9 45.0 50.5 68.0 61.5 20.3 21.7 23.7 25.4 20.8 23.6 23.1 22.1 23.6 21.7 22.7 22.6 18.9 0.0 10.3 5.2 21.0 13.8 22.4 59.8 9.6 21.2 17.3 21.3 70.4 37.1 32.3 36.8 27.1 94.3 10.7 20.4 119.3 35.0 67.1 20.0 16.6 18.4 28.3 17.7 4.2 38.0 42.1 19.2 19.9 19.5 22.2 25.8 17.2 105.0 35.6 15.2 5.9 20.6 44.7 13.4 5.5 16.3 14.3 10.8 7.2 3.7 42.1 25.1 20.6 4.5 6.1 31.7 18.4 18.8 17.3 21.9 32.1 133.6 26.2 28.4 26.3 19.5 25.5 55.3 27.4 27.1 23.3 80.7 18.5 66.9 36.1 29.4 MRPL47 "CGI-204, NCM1" ENSG00000136522 "Mitochondrial ribosomal protein L47" Q9HD33 3 179588285-179604649 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 399.7;Spermatocytes: 301.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037553, HPA047779" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA037553: AB_10671375, HPA047779: AB_2680154" "unprognostic (6.37e-2)" "prognostic favorable (6.44e-4)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.15e-4)" "unprognostic (1.53e-1)" "unprognostic (8.55e-3)" "unprognostic (1.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.58e-1)" "unprognostic (8.03e-3)" "unprognostic (1.70e-2)" "unprognostic (1.29e-2)" "unprognostic (5.64e-2)" "unprognostic (3.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.71e-1)" "unprognostic (8.84e-2)" 27.2 34.8 30.6 24.0 31.7 48.8 27.2 34.2 41.1 19.4 34.2 32.1 23.7 23.0 22.8 31.8 18.9 18.5 54.9 29.4 34.7 44.4 35.5 20.1 30.0 32.0 31.8 16.6 17.4 33.9 24.0 22.2 32.6 20.6 31.8 26.6 21.1 18.9 52.5 21.5 22.6 24.7 33.3 24.3 26.2 53.1 32.6 33.3 21.0 56.9 30.4 32.0 21.7 34.2 128.6 48.6 83.0 76.7 51.5 53.5 95.2 73.2 65.1 112.3 93.2 198.6 51.8 104.7 140.6 62.5 137.2 94.5 103.5 76.9 120.5 121.0 90.9 99.8 46.1 112.5 99.8 182.2 54.2 49.6 65.7 83.4 84.7 53.1 77.2 95.9 59.5 81.4 88.1 98.9 98.4 168.4 144.3 115.4 114.6 102.7 81.1 175.3 120.4 79.6 71.8 83.5 80.7 128.6 151.2 61.9 198.6 136.6 61.6 60.7 87.4 77.1 204.5 102.1 182.4 229.3 70.7 147.4 75.8 38.2 32.4 44.2 31.7 43.8 32.2 35.1 35.1 34.7 48.4 31.8 30.4 31.7 8.5 41.5 54.4 41.9 48.9 35.8 30.6 31.7 34.2 41.1 29.4 34.7 32.0 31.8 32.6 33.3 32.6 34.2 45.3 22.4 21.7 5.5 51.4 74.9 82.0 179.7 38.7 20.2 36.4 33.4 89.7 54.3 78.6 57.0 10.4 100.0 61.2 46.3 258.2 112.3 399.7 72.8 56.0 55.5 54.9 62.9 7.1 115.9 109.6 51.8 36.2 50.0 56.4 34.0 44.3 62.5 99.3 10.1 9.2 52.8 105.8 42.4 55.7 95.4 42.9 53.5 48.0 4.7 80.3 43.4 39.1 7.1 12.4 118.7 53.6 49.2 54.6 72.6 45.2 201.7 85.5 26.0 59.2 57.9 68.2 301.2 54.0 52.2 70.5 104.1 57.8 102.3 71.9 83.8 MRPL50 "FLJ20493, MRP-L50" ENSG00000136897 "Mitochondrial ribosomal protein L50" Q8N5N7 9 101387633-101398618 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 203.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022925 Approved Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria Cytosol "HPA022925: AB_1854117" "unprognostic (6.17e-2)" "unprognostic (6.03e-2)" "unprognostic (4.65e-2)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "unprognostic (1.27e-2)" "unprognostic (5.75e-3)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" "unprognostic (6.99e-2)" "unprognostic (1.19e-2)" "unprognostic (3.46e-2)" "prognostic favorable (1.21e-10)" "unprognostic (7.06e-2)" "unprognostic (2.39e-1)" "unprognostic (1.01e-1)" "unprognostic (1.06e-1)" 9.6 16.0 10.6 8.3 11.6 4.0 11.8 15.8 13.5 7.8 9.7 8.1 8.6 7.8 12.7 7.1 8.0 7.2 14.5 11.1 11.2 13.3 14.0 7.1 11.0 10.0 11.1 11.9 11.9 13.1 8.9 8.2 10.3 9.8 8.6 19.0 8.4 8.0 10.9 5.7 8.3 7.2 10.8 9.4 10.1 6.5 10.8 8.6 9.1 14.9 11.6 10.3 5.7 11.5 12.6 14.9 23.3 13.6 16.0 17.0 16.5 16.0 15.2 17.3 14.6 20.4 12.3 30.6 10.1 12.5 21.3 28.4 23.0 19.2 18.6 18.6 13.7 15.0 16.4 59.0 17.2 27.5 13.9 14.0 21.9 14.0 25.5 13.0 15.9 15.9 32.1 16.1 17.8 20.7 17.0 20.3 25.6 73.9 20.2 17.1 33.1 19.2 25.8 13.7 22.4 16.6 17.0 16.9 18.5 15.9 11.9 17.0 13.2 11.8 17.6 20.7 15.4 12.0 38.0 12.8 15.0 16.0 16.9 9.8 12.5 9.9 13.9 15.2 16.8 20.6 19.3 16.0 16.3 19.5 22.4 20.3 2.2 14.7 15.9 13.0 23.1 16.8 10.6 11.6 15.8 13.5 11.1 11.2 10.0 11.1 10.3 10.8 10.8 11.5 33.0 16.0 20.8 11.4 46.4 90.5 133.6 203.4 51.2 19.1 31.0 31.9 76.0 35.8 86.9 57.0 12.5 74.8 29.3 15.3 152.6 66.8 10.4 31.4 33.6 41.0 19.8 30.1 12.5 69.4 73.8 46.9 23.4 25.7 44.5 24.0 32.2 43.9 51.9 5.0 15.1 28.0 162.8 25.9 50.6 7.4 34.2 28.3 30.2 5.6 32.1 21.9 27.8 8.0 17.2 66.8 32.7 40.6 39.4 112.8 26.4 186.5 67.4 18.2 46.0 37.6 52.4 44.7 39.3 41.6 99.3 76.5 43.2 63.1 34.3 130.4 MRPL51 "bMRP64, CDA09, HSPC241, MRP64" ENSG00000111639 "Mitochondrial ribosomal protein L51" Q4U2R6 12 6491886-6493841 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 950.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039923 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039923: AB_10795373" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.97e-1)" "unprognostic (1.44e-2)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (3.81e-3)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (1.43e-1)" "unprognostic (3.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.36e-1)" "unprognostic (2.62e-1)" "unprognostic (1.17e-1)" "unprognostic (8.33e-2)" 95.7 128.2 151.3 77.1 158.1 88.1 83.2 161.6 239.9 88.4 151.8 119.2 65.5 80.2 99.3 146.1 82.4 49.4 252.5 151.0 159.2 157.9 158.5 75.9 104.5 158.5 155.3 78.9 119.7 128.2 109.3 70.0 158.6 105.8 91.5 64.4 87.0 63.7 262.7 93.2 85.9 70.9 157.3 99.6 112.3 233.3 156.2 131.4 90.6 240.5 126.7 104.2 90.7 165.5 263.4 286.8 334.5 244.1 235.8 212.8 390.6 187.7 222.5 277.1 258.1 398.4 325.4 376.3 124.4 278.2 330.2 220.8 272.4 298.1 409.8 456.3 294.7 256.3 415.2 340.8 217.7 352.4 206.2 205.7 237.2 251.1 331.4 357.9 265.4 291.0 186.1 114.0 356.2 374.3 356.7 463.3 707.1 471.1 287.1 248.2 384.5 264.8 232.6 319.7 126.4 222.2 320.9 355.8 305.4 662.7 107.6 323.7 218.1 226.0 318.5 188.8 406.3 109.0 177.7 850.0 279.8 243.3 305.6 224.5 202.0 231.8 181.6 196.4 206.8 229.3 193.2 201.4 234.6 211.9 196.4 201.4 77.5 203.3 197.8 318.4 234.4 294.0 151.3 158.1 161.6 239.9 151.0 159.2 158.5 155.3 158.6 157.3 156.2 165.5 98.5 105.8 77.4 11.4 113.8 136.1 167.4 410.5 131.5 47.1 180.4 265.8 302.6 178.7 195.4 171.0 12.5 277.1 111.8 126.2 469.5 239.1 950.6 159.7 159.1 129.5 149.9 152.5 9.6 277.8 404.4 146.6 65.7 122.2 92.6 202.3 144.2 374.1 263.9 43.7 10.0 188.3 244.1 147.6 117.9 523.6 153.1 109.4 193.9 10.3 301.6 133.8 121.5 7.1 16.1 247.4 160.3 147.8 171.9 250.0 153.9 538.2 157.5 47.5 111.7 132.7 155.7 534.2 195.4 188.4 157.0 215.5 98.1 244.4 221.2 182.8 MRPL53 ENSG00000204822 "Mitochondrial ribosomal protein L53" Q96EL3 2 74471982-74472687 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034612, HPA056185" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA034612: , HPA056185: AB_2683060" "unprognostic (2.22e-2)" "unprognostic (1.94e-2)" "unprognostic (2.81e-2)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (2.88e-2)" "prognostic unfavorable (7.36e-5)" "unprognostic (3.60e-2)" "unprognostic (1.24e-1)" "unprognostic (4.06e-2)" "prognostic favorable (1.37e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.16e-8)" "unprognostic (8.76e-2)" "unprognostic (2.79e-1)" "unprognostic (4.13e-1)" "unprognostic (2.45e-2)" 60.9 82.9 68.8 46.8 72.2 61.8 38.9 77.0 98.9 31.3 79.2 41.5 48.0 28.7 39.1 41.0 50.2 34.0 114.4 67.1 72.3 54.5 65.1 34.2 78.4 72.3 69.3 61.5 118.0 72.1 35.1 34.8 72.7 46.0 20.3 27.1 107.1 36.2 169.7 27.3 45.9 24.4 74.2 54.7 55.0 23.1 70.2 50.3 47.1 89.0 42.3 44.7 27.0 76.5 101.5 271.0 60.0 58.5 77.9 69.7 103.4 79.8 73.7 70.5 60.9 224.7 130.1 87.6 78.8 61.4 97.3 76.3 32.5 105.7 24.5 174.6 188.3 77.7 115.6 133.7 70.7 88.4 85.6 96.7 75.1 90.4 59.0 82.3 75.3 109.0 93.0 156.6 63.8 316.5 118.6 163.3 57.5 166.0 204.5 89.1 196.0 212.9 88.9 115.6 103.5 128.0 74.1 195.6 137.3 40.8 102.3 111.1 83.6 115.9 119.6 101.7 135.2 292.3 260.6 141.1 116.4 94.8 125.8 244.9 293.8 133.8 168.2 277.6 188.5 350.0 215.9 173.1 250.3 367.5 282.0 211.4 185.5 167.6 271.8 360.3 275.3 345.5 68.8 72.2 77.0 98.9 67.1 72.3 72.3 69.3 72.7 74.2 70.2 76.5 5.2 9.6 23.2 4.6 18.0 17.2 6.0 9.7 12.0 2.0 24.0 16.4 1.6 4.3 12.1 11.0 0.0 14.7 10.5 29.5 21.5 32.8 8.9 7.2 4.3 11.2 39.7 18.9 3.4 56.9 17.5 10.9 15.3 4.7 33.6 3.0 16.1 23.8 18.0 1.7 3.5 27.2 6.1 25.9 23.9 2.3 8.7 15.6 26.6 2.8 35.8 4.6 15.5 2.0 7.1 35.8 43.5 4.5 34.8 4.9 41.8 45.3 46.1 4.0 6.6 7.7 11.2 11.2 6.8 16.6 25.1 15.7 14.6 3.3 21.7 6.9 MRPL57 MRP63 ENSG00000173141 "Mitochondrial ribosomal protein L57" Q9BQC6 13 21176658-21179084 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 719.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039779, HPA059370" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039779: AB_10673362, HPA059370: AB_2683993" "unprognostic (1.00e-1)" "unprognostic (1.92e-1)" "unprognostic (4.32e-2)" "unprognostic (9.57e-3)" "unprognostic (1.51e-1)" "unprognostic (5.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.68e-2)" "prognostic favorable (8.35e-4)" "unprognostic (7.65e-2)" "unprognostic (2.01e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-1)" "unprognostic (1.10e-1)" "unprognostic (6.78e-2)" 13.6 27.0 16.0 8.4 16.1 11.0 13.9 16.8 18.3 12.1 15.3 17.2 10.8 12.9 11.7 17.6 13.4 5.2 28.1 16.7 20.5 24.7 29.1 11.7 8.8 16.8 17.0 16.1 16.9 15.3 27.9 7.1 16.9 17.9 6.8 15.5 14.9 8.4 38.8 14.9 13.7 5.6 16.3 14.8 16.2 11.8 17.3 17.0 16.4 18.3 6.6 14.8 12.4 16.5 16.9 30.3 20.8 19.0 15.6 12.8 21.9 20.0 12.4 18.5 13.9 39.6 30.6 9.7 22.7 12.5 14.5 28.7 18.3 19.0 13.9 25.8 30.8 44.2 21.3 45.3 23.2 24.6 21.3 13.2 20.8 14.8 13.9 11.2 17.9 39.0 19.5 12.4 13.2 59.3 53.7 64.8 15.1 54.8 35.0 32.1 31.4 17.2 23.1 20.3 41.4 19.4 16.2 20.1 31.2 14.0 20.2 22.8 12.6 9.6 17.9 20.5 17.9 17.2 14.9 17.7 8.6 28.5 24.6 51.1 70.4 56.3 49.8 59.0 56.4 63.1 62.4 53.2 64.0 60.5 69.6 55.6 10.4 54.5 50.4 102.2 70.2 72.4 16.0 16.1 16.8 18.3 16.7 20.5 16.8 17.0 16.9 16.3 17.3 16.5 93.3 80.1 124.4 12.1 95.4 0.0 107.2 0.0 84.2 88.3 172.1 195.7 495.7 140.2 56.3 176.6 45.9 233.6 118.8 171.7 508.7 159.8 256.0 188.6 98.8 91.6 149.5 165.6 16.8 245.1 205.0 94.2 116.2 107.6 72.2 104.5 117.8 478.4 231.4 77.4 21.3 218.9 0.0 126.6 0.0 341.6 115.2 104.1 0.0 8.4 166.2 181.4 109.2 6.6 17.9 171.6 190.7 98.9 141.9 160.4 266.5 719.5 80.9 100.7 52.6 69.0 74.0 83.6 48.9 175.7 0.0 223.1 99.0 179.5 204.1 112.2 MRPS11 "FLJ22512, FLJ23406, HCC-2" ENSG00000181991 "Mitochondrial ribosomal protein S11" P82912 15 88467453-88480776 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043752, HPA050345" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043752: AB_2678653, HPA050345: AB_2681100" "unprognostic (2.66e-1)" "prognostic favorable (3.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (3.21e-1)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "unprognostic (6.45e-2)" "prognostic favorable (4.75e-4)" "unprognostic (8.31e-2)" "unprognostic (3.37e-1)" "unprognostic (1.83e-1)" "unprognostic (9.44e-2)" "unprognostic (7.26e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" 9.4 16.9 12.0 4.0 12.1 2.8 8.6 12.8 18.3 5.3 11.4 9.3 7.9 5.3 3.8 10.9 4.8 4.5 26.1 12.5 12.1 14.0 20.5 5.2 5.6 12.7 12.3 3.5 10.5 3.8 7.6 2.3 12.9 7.4 3.5 2.5 6.0 3.4 24.7 7.2 7.4 4.3 11.7 8.0 9.6 9.0 12.7 5.1 9.6 15.0 4.4 8.4 5.6 12.1 10.5 41.1 6.1 10.4 13.8 6.6 16.1 8.3 14.6 10.7 11.5 28.9 16.0 9.7 17.0 7.1 11.3 14.8 17.9 11.5 5.5 12.8 43.8 13.2 23.1 32.0 16.5 4.5 8.3 13.4 11.1 9.2 9.2 5.8 14.3 12.3 9.6 4.3 18.1 45.1 9.3 19.0 16.3 13.4 43.8 19.0 11.6 23.0 15.5 28.4 19.3 9.6 8.6 21.6 33.6 5.3 19.8 24.7 6.8 15.2 16.8 9.9 12.5 8.5 16.5 11.7 18.3 11.2 16.3 31.1 25.1 19.3 15.1 27.6 17.6 27.5 17.2 17.8 29.5 18.2 18.1 17.6 9.5 30.1 17.8 31.9 35.1 26.0 12.0 12.1 12.8 18.3 12.5 12.1 12.7 12.3 12.9 11.7 12.7 12.1 42.1 6.4 20.4 10.4 30.4 22.8 27.5 69.2 31.9 36.9 38.1 47.2 6.3 35.8 39.6 46.0 47.9 91.0 34.6 85.5 135.0 63.9 30.2 27.1 37.8 34.2 24.7 40.6 14.0 66.8 89.7 32.7 25.0 32.5 33.6 40.4 44.6 92.6 90.5 26.9 15.0 60.3 50.8 33.1 24.5 34.2 33.2 31.0 32.0 8.4 65.0 44.4 72.1 16.6 16.8 67.0 70.7 42.5 36.5 32.2 90.8 145.3 29.7 45.1 19.7 29.7 51.8 90.3 42.0 49.1 28.3 89.6 32.3 96.0 64.6 34.5 MRPS17 "HSPC011, MRP-S17, RPMS17" ENSG00000239789 "Mitochondrial ribosomal protein S17" Q9Y2R5 7 55951877-55956500 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 195.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047159 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "HPA047159: AB_2679961" "unprognostic (3.38e-1)" "unprognostic (2.71e-2)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (2.16e-2)" "unprognostic (1.94e-2)" "unprognostic (7.07e-3)" "unprognostic (1.80e-1)" "unprognostic (3.92e-1)" "unprognostic (2.86e-2)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.20e-3)" "unprognostic (7.17e-2)" "unprognostic (2.36e-2)" "unprognostic (2.24e-1)" "unprognostic (2.63e-1)" 9.6 13.6 14.8 7.8 15.0 10.2 11.2 14.8 18.3 7.4 11.6 13.0 8.9 9.9 9.2 13.5 10.1 5.1 20.0 15.6 15.1 16.8 22.1 6.9 9.1 14.3 13.9 9.5 13.6 9.7 8.3 6.5 14.8 10.4 9.8 5.6 9.0 10.5 32.9 8.2 9.1 9.3 13.0 10.2 11.6 11.9 15.9 9.1 8.2 32.7 9.3 11.0 7.8 14.6 195.1 25.3 17.4 36.6 17.3 16.9 22.0 20.6 20.3 25.0 28.4 31.0 26.0 49.3 29.6 16.9 57.9 43.3 38.6 39.3 30.1 20.7 30.0 14.7 35.8 32.2 24.9 37.4 14.5 19.4 31.6 25.0 41.2 18.3 26.5 27.8 57.9 19.2 22.6 21.8 29.9 51.4 37.4 47.7 43.2 23.9 16.8 38.9 40.4 23.4 25.7 22.6 23.4 76.1 28.5 29.6 49.9 29.3 17.9 8.3 40.8 60.2 47.8 16.7 34.2 83.2 8.4 18.9 38.2 3.6 8.7 2.7 10.5 10.7 12.7 17.1 14.4 15.2 13.3 14.2 16.1 14.3 2.3 12.5 11.0 13.2 15.5 7.9 14.8 15.0 14.8 18.3 15.6 15.1 14.3 13.9 14.8 13.0 15.9 14.6 9.6 22.4 11.7 2.6 12.3 0.0 21.3 0.0 26.7 6.7 14.3 14.4 0.0 22.8 14.2 5.5 0.0 30.4 8.7 8.2 29.4 48.1 22.6 18.5 9.5 11.3 4.9 30.9 3.5 54.5 26.2 9.9 23.0 10.0 5.1 10.3 18.9 33.7 19.2 18.5 3.9 15.5 0.0 11.6 0.0 5.5 9.3 9.1 0.0 1.0 20.6 10.6 21.6 3.0 4.6 46.0 14.8 10.9 21.3 19.9 24.2 28.9 13.8 7.0 6.6 10.0 11.2 29.2 12.0 31.2 0.0 21.3 10.7 10.8 21.8 11.9 MRPS18C "CGI-134, FLJ11146, FLJ22967, MRPS18-1" ENSG00000163319 "Mitochondrial ribosomal protein S18C" Q9Y3D5 4 83455932-83469735 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050404 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA050404: AB_2681115" "unprognostic (4.53e-3)" "unprognostic (7.58e-3)" "unprognostic (5.70e-3)" "unprognostic (2.07e-1)" "unprognostic (2.20e-1)" "unprognostic (7.81e-3)" "unprognostic (1.43e-1)" "unprognostic (3.86e-2)" "unprognostic (8.19e-2)" "unprognostic (1.53e-2)" "unprognostic (5.25e-2)" "unprognostic (8.26e-3)" "prognostic favorable (2.90e-5)" "unprognostic (1.52e-2)" "unprognostic (9.86e-2)" "unprognostic (2.24e-2)" "unprognostic (8.31e-3)" 26.5 33.6 27.1 24.0 28.1 26.7 25.1 29.6 42.7 23.2 27.1 26.2 24.8 24.5 17.7 33.6 25.2 14.4 46.7 27.6 29.6 36.4 44.3 21.6 24.6 28.2 27.7 22.3 22.0 20.0 20.1 20.7 28.5 16.8 25.9 19.6 21.1 14.8 85.2 24.2 25.4 21.0 28.2 25.0 24.7 19.5 27.6 25.1 19.4 53.4 32.5 22.7 23.3 29.5 74.4 76.2 58.9 45.3 36.3 24.1 56.9 78.1 39.6 60.5 51.6 136.2 66.8 69.8 86.8 38.5 68.9 39.4 61.0 47.3 71.2 62.7 48.8 59.6 105.6 136.5 49.3 143.2 74.5 25.3 41.0 49.4 58.4 34.9 39.8 86.1 86.5 55.7 39.8 142.9 95.3 87.6 35.4 109.7 53.3 53.6 51.0 55.8 46.4 66.8 61.7 33.2 41.9 82.9 68.0 57.4 36.1 85.7 47.8 53.5 82.5 53.3 104.7 50.7 70.3 158.5 51.1 73.2 67.4 126.2 122.9 196.1 105.9 139.5 108.6 174.7 126.3 117.2 142.5 164.4 130.8 116.5 56.0 117.2 117.3 164.7 195.5 113.5 27.1 28.1 29.6 42.7 27.6 29.6 28.2 27.7 28.5 28.2 27.6 29.5 102.2 51.3 61.3 4.6 67.8 68.1 73.7 169.1 47.8 33.3 54.3 87.2 81.3 90.1 93.3 77.3 37.5 132.4 62.7 57.1 229.0 139.1 117.0 75.9 59.6 77.3 33.6 117.0 8.7 187.8 119.7 57.2 33.1 54.5 109.5 57.1 77.1 180.6 112.6 32.0 8.0 59.3 91.6 65.4 46.8 25.2 82.0 58.1 62.2 6.5 72.9 80.7 96.8 8.0 9.7 134.6 84.1 77.5 63.6 62.7 101.8 211.0 124.7 47.7 59.2 71.2 93.7 109.0 71.6 70.4 64.1 96.2 55.7 70.3 79.9 61.9 MRPS2 CGI-91 ENSG00000122140 "Mitochondrial ribosomal protein S2" Q9Y399 9 135499984-135504673 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029487, HPA057261" Approved Supported Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA029487: , HPA057261: AB_2683385" "unprognostic (3.18e-3)" "unprognostic (9.42e-3)" "unprognostic (1.46e-1)" "unprognostic (7.81e-2)" "unprognostic (3.55e-1)" "unprognostic (8.45e-2)" "unprognostic (1.63e-1)" "unprognostic (5.63e-3)" "unprognostic (3.83e-1)" "unprognostic (2.90e-2)" "unprognostic (4.81e-2)" "unprognostic (7.58e-2)" "prognostic favorable (6.96e-9)" "unprognostic (2.74e-2)" "unprognostic (1.06e-1)" "unprognostic (8.29e-2)" "unprognostic (2.24e-1)" 32.6 56.9 30.7 14.7 31.3 23.2 30.8 30.3 37.9 29.2 34.9 35.4 23.0 29.6 12.9 37.7 35.7 15.8 67.0 31.2 30.2 46.1 79.7 22.0 21.0 29.9 31.3 34.9 45.8 32.2 26.4 16.8 31.1 33.1 17.3 7.7 31.3 21.2 75.5 39.1 28.1 15.2 29.7 32.0 39.3 17.0 33.1 16.2 25.8 50.4 17.7 33.8 28.8 30.8 59.9 98.4 35.3 48.0 39.1 43.5 60.0 43.0 39.0 71.7 53.0 149.0 55.4 75.4 57.2 40.1 75.8 132.6 88.9 101.4 27.7 46.2 137.4 37.4 96.1 101.8 68.4 76.6 44.3 58.6 77.6 78.3 55.6 45.7 67.9 74.2 125.1 54.3 42.3 185.8 73.9 133.7 80.2 110.8 153.9 81.3 57.3 159.5 59.9 50.8 104.9 55.2 58.8 110.9 63.2 23.6 92.4 60.5 42.4 52.3 58.4 90.3 78.8 58.9 124.5 84.1 53.0 69.2 49.1 8.4 28.4 13.6 30.0 27.5 34.5 34.4 30.1 32.4 29.1 34.3 32.4 32.9 2.4 28.7 24.0 25.1 41.8 26.4 30.7 31.3 30.3 37.9 31.2 30.2 29.9 31.3 31.1 29.7 33.1 30.8 23.8 12.8 14.1 4.9 32.5 44.7 38.8 55.0 33.0 22.2 37.3 51.7 31.2 42.9 31.6 12.9 6.2 71.3 19.0 21.5 72.4 50.7 14.7 27.8 34.2 32.6 21.7 41.4 4.6 38.6 65.8 27.9 21.4 77.7 8.2 37.9 21.8 46.5 42.5 25.2 5.9 37.9 28.5 17.6 15.4 32.5 24.2 21.0 19.6 1.9 31.7 24.8 20.6 4.0 4.5 39.9 27.1 23.0 38.6 48.6 36.3 84.5 14.7 17.0 32.9 27.1 29.4 13.3 21.5 47.1 45.7 37.4 23.4 77.5 55.7 35.5 MRPS21 ENSG00000266472 "Mitochondrial ribosomal protein S21" P82921 1 150293861-150308979 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 863.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078289 Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA078289: AB_2686881" "unprognostic (3.48e-2)" "unprognostic (1.94e-2)" "unprognostic (5.46e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (1.15e-2)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (4.13e-2)" "unprognostic (9.71e-2)" "unprognostic (7.59e-2)" "unprognostic (2.12e-2)" "unprognostic (4.02e-2)" "unprognostic (3.97e-2)" "unprognostic (1.46e-1)" 46.8 76.7 91.7 35.7 93.8 39.0 51.7 92.9 121.4 48.7 97.4 51.8 38.4 46.7 53.7 54.5 46.3 27.6 72.7 93.2 95.0 67.1 59.9 39.2 42.8 93.8 92.7 56.6 51.1 65.4 70.1 32.5 94.5 51.5 28.9 42.3 43.7 39.1 55.6 45.0 45.2 38.7 89.0 53.3 52.1 52.2 95.2 49.0 53.1 66.5 46.6 47.9 45.8 92.3 112.7 88.4 112.9 57.5 108.3 108.2 93.9 80.5 69.1 77.0 74.5 18.0 101.6 111.9 54.2 89.3 22.8 102.9 96.8 86.4 67.8 77.7 125.9 64.3 133.4 137.0 84.7 98.4 53.8 119.2 87.0 93.4 105.8 47.0 100.3 96.8 106.7 144.3 107.1 255.8 84.3 89.1 196.0 216.3 159.3 75.9 59.0 195.8 93.7 79.9 83.7 182.1 68.4 131.9 136.4 126.3 73.4 143.0 71.7 28.1 56.7 81.6 90.9 120.4 136.4 112.7 39.5 53.1 58.3 41.1 78.4 50.7 70.1 79.7 86.6 116.8 92.7 82.5 89.1 102.1 103.8 89.6 17.8 71.5 73.6 136.2 97.2 104.9 91.7 93.8 92.9 121.4 93.2 95.0 93.8 92.7 94.5 89.0 95.2 92.3 124.7 112.2 115.8 24.8 152.7 120.3 199.9 466.6 191.8 72.6 189.3 246.4 295.6 201.6 227.8 263.0 33.3 283.8 110.4 114.4 526.3 226.2 863.2 217.2 216.0 150.2 138.5 151.7 31.8 311.4 245.5 172.3 152.4 155.7 132.9 157.8 189.2 366.9 288.2 48.8 34.7 141.6 266.5 196.2 162.3 605.4 230.2 143.7 181.5 18.7 234.1 140.3 118.4 23.1 27.1 300.8 133.1 233.2 156.5 197.6 230.1 703.7 291.7 59.5 98.6 115.4 211.1 276.4 112.1 262.6 147.2 235.2 144.4 183.8 168.5 200.9 MRPS24 "HSPC335, MRP-S24" ENSG00000062582 "Mitochondrial ribosomal protein S24" Q96EL2 7 43866558-43869893 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 455.8" "Group enriched" "Detected in many" 5 "Basal squamous epithelial cells: 109.3;Erythroid cells: 54.7;Gastric mucus-secreting cells: 84.6;Plasma cells: 184.7;Squamous epithelial cells: 204.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073947 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" "HPA073947: " "unprognostic (1.35e-1)" "unprognostic (2.41e-2)" "unprognostic (1.30e-1)" "unprognostic (3.44e-1)" "unprognostic (7.32e-2)" "unprognostic (8.63e-3)" "unprognostic (9.42e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (2.03e-1)" "unprognostic (6.86e-3)" "unprognostic (9.58e-3)" "unprognostic (1.71e-2)" "prognostic favorable (9.89e-4)" "unprognostic (2.87e-1)" "unprognostic (9.08e-2)" "unprognostic (7.37e-2)" "unprognostic (1.95e-1)" 81.4 160.7 98.6 41.6 98.8 93.6 81.9 103.5 116.1 82.3 103.6 107.5 71.6 79.2 43.3 148.5 79.7 34.0 233.6 100.1 104.1 142.9 172.6 64.4 49.4 96.2 97.7 95.8 151.1 92.0 68.3 39.7 96.2 82.4 47.0 31.3 101.2 40.1 455.8 91.7 77.7 37.8 97.1 76.9 126.8 83.5 106.1 47.9 65.3 281.0 48.3 87.3 88.4 94.7 165.2 260.4 80.2 165.8 82.7 141.4 132.3 155.4 386.0 206.2 203.3 236.7 152.8 140.1 182.8 160.1 278.8 204.7 115.8 142.9 160.9 131.8 287.2 86.1 286.2 287.7 122.7 140.5 106.5 133.8 142.6 161.0 192.1 130.8 120.3 136.8 281.4 103.3 131.6 262.7 170.6 313.4 200.5 184.8 261.0 137.3 113.9 540.5 150.9 139.3 159.5 180.4 156.7 386.3 162.2 102.9 261.5 252.1 96.8 191.6 263.6 116.1 225.7 310.4 258.8 182.5 232.3 186.1 305.7 41.4 175.4 95.6 114.1 181.6 124.8 222.5 167.5 137.5 241.0 195.6 165.0 142.6 14.7 124.1 181.0 162.8 214.1 177.5 98.6 98.8 103.5 116.1 100.1 104.1 96.2 97.7 96.2 97.1 106.1 94.7 1.2 6.4 19.1 0.0 24.1 4.5 2.6 2.5 109.3 4.9 8.2 5.3 0.4 8.6 13.2 5.5 6.2 1.4 2.9 1.8 3.9 7.1 1.8 9.4 16.5 7.8 4.2 54.7 0.0 0.7 3.8 20.4 84.6 12.1 3.8 2.3 8.9 21.7 1.2 0.0 0.0 1.5 0.0 8.6 6.3 1.0 0.3 24.4 3.6 0.0 3.1 0.9 4.1 0.0 0.0 2.9 0.7 0.7 184.7 1.8 1.6 1.9 21.9 7.7 0.0 1.7 13.8 1.0 1.4 204.4 5.8 1.9 19.4 1.7 2.1 3.2 MRPS28 "HSPC007, MRP-S28, MRPS35" ENSG00000147586 "Mitochondrial ribosomal protein S28" Q9Y2Q9 8 79918717-80030289 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 359.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027202 Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA027202: AB_1854126" "unprognostic (3.63e-3)" "unprognostic (6.41e-2)" "unprognostic (9.61e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-3)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (4.55e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "prognostic favorable (1.20e-6)" "unprognostic (4.48e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-1)" "unprognostic (7.18e-2)" 47.5 88.8 65.1 32.9 67.7 29.1 47.5 70.0 85.3 33.3 73.0 52.9 30.9 27.3 38.3 41.0 35.2 28.8 104.0 64.0 70.2 79.2 110.9 30.4 37.7 70.1 69.8 28.6 32.3 69.6 40.4 40.9 70.1 31.3 41.0 51.7 35.4 33.4 160.3 29.0 29.4 32.8 69.7 26.7 35.3 24.3 66.9 44.9 53.7 137.7 37.9 39.0 30.7 75.3 85.2 84.1 73.0 17.3 60.9 77.2 79.8 94.3 85.7 122.1 104.2 74.0 66.4 107.2 105.3 75.6 124.2 68.5 102.1 105.5 99.0 85.3 89.8 128.8 74.8 114.4 67.7 57.6 55.3 66.4 88.9 71.8 97.4 67.1 81.0 85.2 93.4 42.3 123.7 81.3 133.8 93.5 29.8 219.5 139.5 89.9 58.1 62.0 158.0 81.8 34.8 58.6 41.1 359.5 91.1 83.8 86.6 68.1 59.0 45.8 116.4 81.6 82.7 46.5 81.4 97.2 77.4 66.7 36.8 95.4 53.8 29.1 48.2 77.3 52.3 51.2 52.8 59.4 98.8 54.4 64.1 62.1 11.1 71.5 70.1 111.1 73.0 49.8 65.1 67.7 70.0 85.3 64.0 70.2 70.1 69.8 70.1 69.7 66.9 75.3 32.5 22.4 22.2 57.8 20.8 35.2 19.5 124.5 36.5 10.9 23.4 28.1 51.6 42.9 67.0 33.1 4.2 78.7 20.9 18.1 101.8 67.3 15.1 28.5 16.1 26.2 37.3 21.7 39.0 47.4 74.3 21.2 17.9 24.1 50.0 10.5 23.9 65.5 49.5 5.0 42.5 23.5 69.2 25.5 28.5 10.4 17.7 26.9 44.4 70.3 40.0 23.7 26.8 93.5 81.8 36.0 20.6 22.2 19.9 13.4 24.5 126.9 79.7 17.2 32.9 31.1 26.1 18.6 33.4 41.6 37.8 59.4 20.0 23.2 36.4 16.0 MRPS33 CGI-139 ENSG00000090263 "Mitochondrial ribosomal protein S33" Q9Y291 7 141002610-141015228 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 354.1;Proximal tubular cells: 386.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030425 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA030425: AB_10602030" "unprognostic (9.83e-2)" "unprognostic (2.91e-1)" "unprognostic (2.19e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-2)" "unprognostic (4.03e-2)" "unprognostic (5.99e-2)" "unprognostic (3.82e-1)" "unprognostic (3.66e-2)" "unprognostic (4.55e-3)" "unprognostic (6.94e-3)" "unprognostic (4.26e-1)" "unprognostic (9.80e-3)" "unprognostic (1.16e-1)" "unprognostic (9.52e-2)" "unprognostic (1.01e-1)" "unprognostic (3.52e-2)" 37.7 64.4 43.9 27.5 46.9 25.0 58.5 46.4 68.8 30.3 47.7 65.3 50.1 25.5 79.1 46.3 35.1 22.4 114.5 45.3 48.0 72.7 83.7 20.8 41.0 46.6 45.9 35.2 67.6 81.2 49.1 24.4 48.0 36.6 69.8 29.4 50.0 31.2 173.7 35.9 44.5 26.5 46.8 30.9 44.3 45.3 45.4 41.9 51.7 171.5 43.5 36.9 30.2 47.8 79.0 110.5 61.8 65.7 77.1 104.9 67.6 69.5 68.7 65.1 73.2 67.6 104.9 107.7 100.0 67.3 140.9 50.5 69.5 102.6 89.3 96.6 83.1 67.8 20.6 130.8 93.8 98.3 39.2 99.8 103.0 100.8 89.4 73.3 53.9 108.4 113.3 84.0 128.2 124.8 110.1 153.3 129.3 140.0 125.6 28.4 48.5 186.1 114.9 99.8 111.7 88.2 93.7 93.2 145.5 65.3 79.4 90.8 41.8 56.6 38.4 137.5 75.8 128.3 155.7 126.8 125.3 99.8 95.1 13.0 47.6 37.9 48.9 68.7 61.9 85.4 85.5 61.1 79.5 66.8 98.3 83.5 4.9 79.8 60.5 93.8 77.3 61.2 43.9 46.9 46.4 68.8 45.3 48.0 46.6 45.9 48.0 46.8 45.4 47.8 30.3 38.5 43.6 11.1 54.6 42.6 72.1 207.7 51.2 27.1 101.1 104.6 333.5 82.9 96.5 114.0 31.3 145.4 39.5 96.9 354.1 101.0 136.8 124.2 60.1 42.8 89.7 46.3 8.9 136.8 133.0 55.3 50.0 70.6 48.2 71.4 42.5 221.8 114.1 57.2 9.1 148.3 109.9 59.8 38.1 41.0 57.8 45.7 76.5 8.4 97.4 47.8 51.5 9.0 18.0 95.6 80.6 42.5 88.9 67.1 199.0 386.1 122.5 32.9 19.7 41.0 57.1 157.7 50.8 84.4 45.7 116.8 49.6 82.8 202.3 79.0 MRPS36 "DC47, MRP-S36" ENSG00000134056 "Mitochondrial ribosomal protein S36" P82909 5 69217760-69230158 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 546.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035802, HPA056795" Supported Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA035802: AB_10600933, HPA056795: AB_2683237" "unprognostic (1.19e-1)" "unprognostic (6.78e-3)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (2.96e-3)" "unprognostic (1.99e-1)" "unprognostic (7.49e-2)" "unprognostic (1.49e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (3.90e-1)" "prognostic favorable (5.02e-6)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.37e-2)" "unprognostic (4.84e-3)" 20.3 18.4 20.1 12.7 20.3 21.0 16.5 21.3 26.3 12.7 20.2 23.6 24.1 12.8 15.4 20.3 12.7 10.4 67.3 20.1 21.5 49.2 38.0 14.7 15.1 20.3 20.6 12.4 14.7 31.3 9.8 13.0 20.6 14.4 24.3 18.9 13.7 12.1 47.0 12.6 24.0 12.4 20.3 11.6 21.8 8.6 20.8 15.7 17.2 67.7 16.7 16.6 14.0 20.5 29.2 27.6 19.1 26.4 32.8 33.1 50.3 25.6 24.5 32.1 39.4 38.6 31.8 31.2 51.9 21.8 71.8 29.3 32.1 38.8 31.7 36.8 33.6 21.3 31.4 43.4 38.7 22.9 27.9 34.6 27.3 30.7 14.5 33.4 24.0 31.9 25.7 22.9 28.7 31.8 35.3 34.9 14.2 26.8 31.9 20.6 33.2 47.9 56.4 32.5 26.6 25.9 26.2 37.9 46.3 30.9 29.0 32.9 17.6 14.3 24.5 32.0 44.5 23.9 41.9 41.6 25.0 42.1 19.1 36.3 22.1 29.3 22.7 32.0 25.4 31.1 25.7 25.8 27.9 25.0 22.8 24.7 25.1 26.5 30.2 27.4 40.3 17.7 20.1 20.3 21.3 26.3 20.1 21.5 20.3 20.6 20.6 20.3 20.8 20.5 64.5 115.4 83.6 16.3 76.5 81.4 101.1 204.0 83.1 26.3 72.4 109.3 333.1 97.2 104.3 88.3 14.6 126.8 67.5 220.5 401.1 118.4 127.7 123.3 79.5 57.2 92.8 97.2 20.4 139.5 192.4 68.6 67.2 113.0 56.4 41.4 52.1 216.1 127.1 28.6 21.4 162.8 120.1 102.4 67.5 45.2 64.7 72.9 106.7 10.3 142.0 61.8 56.7 10.6 17.1 137.1 190.1 69.2 60.5 100.5 256.6 546.3 86.4 45.9 72.3 78.7 92.3 66.1 37.9 86.9 76.9 123.3 64.2 76.9 168.1 114.6 MRPS7 "MRP-S, RP-S7, RPMS7" ENSG00000125445 "Mitochondrial ribosomal protein S7" Q9Y2R9 17 75261674-75266376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 454.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022522, HPA023007" Supported Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA022522: AB_1854131, HPA023007: AB_1854132" "unprognostic (1.24e-1)" "unprognostic (4.74e-2)" "prognostic favorable (1.12e-4)" "unprognostic (5.82e-3)" "unprognostic (3.62e-2)" "unprognostic (5.05e-3)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (4.95e-2)" "unprognostic (8.56e-3)" "unprognostic (1.03e-1)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (8.56e-2)" "unprognostic (1.76e-1)" "unprognostic (4.15e-1)" 44.3 58.4 55.5 38.1 55.9 32.9 41.2 60.0 61.9 28.7 59.0 49.9 48.9 28.3 24.4 58.5 39.2 27.1 129.0 55.1 59.3 66.1 64.6 32.4 41.3 57.2 57.5 29.2 39.0 76.6 36.0 40.8 57.6 34.1 48.2 47.3 41.1 35.7 201.3 32.6 40.0 33.8 57.8 39.5 47.5 29.9 59.8 33.6 35.9 212.3 43.6 42.6 35.0 56.3 113.8 188.6 78.8 57.6 63.9 35.7 139.4 73.3 60.9 137.4 101.1 209.8 93.5 96.4 66.4 79.8 91.4 104.5 122.3 135.8 82.2 50.8 173.5 131.8 133.6 201.3 62.5 134.3 69.6 60.0 131.8 108.6 109.6 69.2 177.3 117.8 130.1 93.3 91.1 203.5 151.8 104.7 85.4 157.7 176.2 100.7 229.5 145.2 128.4 124.6 135.8 122.8 93.8 249.9 150.0 83.9 188.4 108.7 72.2 124.0 125.3 68.2 155.7 97.9 61.5 106.6 89.5 88.3 96.9 43.2 155.1 48.2 115.7 161.6 124.2 140.2 112.0 126.0 172.0 128.1 128.6 120.7 11.0 130.5 138.5 164.9 141.6 236.0 55.5 55.9 60.0 61.9 55.1 59.3 57.2 57.5 57.6 57.8 59.8 56.3 44.1 51.3 48.3 12.1 69.3 39.5 75.1 148.1 37.0 65.8 56.5 63.0 77.8 70.1 74.3 57.0 98.0 192.9 63.3 94.1 230.9 112.9 139.2 50.9 43.2 55.6 47.5 61.4 11.8 104.1 175.3 50.2 55.5 43.5 39.3 68.6 45.3 91.7 148.8 47.1 14.0 84.3 77.3 60.0 35.6 454.3 48.4 52.6 42.7 3.7 107.0 85.6 73.2 9.5 11.3 89.8 69.3 39.9 87.7 85.3 129.2 219.3 81.0 114.4 59.2 40.8 73.0 60.5 68.5 68.5 41.9 137.9 53.8 110.0 133.8 77.4 MSRB2 "CBS-1, CBS1, CGI-131, MSRB, PILB" ENSG00000148450 "Methionine sulfoxide reductase B2" Q9Y3D2 10 23095579-23122013 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 269.1;Proximal tubular cells: 463.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027933 Enhanced "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027933: AB_10601867" "unprognostic (4.89e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-3)" "unprognostic (3.47e-3)" "unprognostic (4.51e-1)" "unprognostic (9.26e-3)" "unprognostic (1.62e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (6.07e-3)" "unprognostic (3.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.03e-1)" "unprognostic (1.82e-2)" "unprognostic (6.74e-2)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" 16.2 17.3 29.0 6.6 30.8 7.7 11.0 29.5 40.5 13.2 26.8 22.7 9.4 15.8 16.8 10.8 17.6 7.7 61.6 29.5 32.2 19.0 31.0 9.8 3.9 30.4 30.9 11.9 5.4 23.1 14.4 8.2 30.5 14.3 11.4 13.1 9.1 19.5 42.2 5.5 11.9 16.3 29.1 9.3 11.4 3.9 30.8 8.4 14.1 51.7 4.1 17.1 11.0 29.4 7.3 10.4 19.0 11.6 19.3 17.3 5.7 11.5 6.4 7.2 8.3 7.2 15.5 5.9 10.0 24.6 10.9 4.6 6.3 8.6 5.9 40.3 7.0 4.3 17.7 4.1 27.2 0.9 5.0 22.2 14.3 8.4 2.0 15.7 10.4 11.5 5.9 10.3 16.0 21.9 7.0 5.5 10.5 41.4 6.0 8.0 10.9 1.5 9.1 2.8 3.8 26.1 14.2 12.4 23.9 15.9 8.4 17.1 7.7 6.2 5.8 14.0 6.9 13.3 4.4 0.2 8.8 12.7 5.3 0.9 1.4 2.3 0.3 1.1 0.3 0.2 0.3 0.2 0.8 0.0 0.6 0.4 3.4 0.2 0.8 1.6 0.4 0.2 29.0 30.8 29.5 40.5 29.5 32.2 30.4 30.9 30.5 29.1 30.8 29.4 29.0 0.0 16.4 27.1 11.4 18.2 52.1 33.1 59.2 68.2 69.6 79.1 269.1 80.1 21.1 90.1 22.9 116.1 10.6 86.7 176.1 130.4 1.4 49.3 71.6 34.4 55.7 30.7 9.5 63.4 61.2 70.7 23.4 46.5 29.2 114.0 42.1 195.4 109.6 112.7 16.9 54.8 26.4 70.5 25.1 4.4 49.7 54.2 72.9 11.2 29.7 126.6 7.2 14.6 26.1 90.3 79.6 62.4 24.7 34.9 80.8 463.9 24.3 57.5 59.2 52.6 71.6 4.4 7.7 66.7 17.5 69.6 13.5 60.9 71.0 54.3 MT-ATP6 "ATP6, ATPase-6, MTATP6, RP, Su6m" ENSG00000198899 "Mitochondrially encoded ATP synthase membrane subunit 6" P00846 MT 8527-9207 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Cardiomyopathy, Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, Neuropathy, Primary mitochondrial disease, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 240231.8" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 183462.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15099.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 15099.8" "Cell line enriched" "Detected in all" 4 "HeLa: 81002.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.97e-1)" "unprognostic (4.16e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" "unprognostic (8.45e-3)" "unprognostic (1.66e-1)" "prognostic favorable (3.79e-4)" "unprognostic (6.47e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-2)" "prognostic favorable (7.64e-4)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.37e-1)" "unprognostic (3.56e-1)" "unprognostic (2.52e-3)" 30620.5 49902.8 78564.9 5757.5 78683.9 5263.3 24700.9 71753.6 111983.3 10531.0 92461.0 34888.0 15959.6 12648.9 6224.7 18979.9 12132.1 5215.3 240231.8 73845.3 79126.1 97663.8 108393.4 13251.1 4613.5 94236.1 80705.7 11001.6 26731.7 15286.5 17490.5 7337.2 87375.8 26534.4 11997.9 12678.8 19672.9 7061.2 110786.8 21566.0 29555.6 5826.0 66562.7 15489.6 42384.5 15009.7 82151.7 2880.7 17077.7 67112.7 4344.5 21210.2 12968.0 67597.2 5618.9 8971.4 6145.8 9667.8 11469.9 2606.5 4002.9 8017.4 1465.1 1068.3 1770.2 10629.5 5953.7 9842.8 3325.6 4356.6 1640.3 11849.7 653.2 6255.4 1954.9 7091.2 5605.0 8645.7 81002.5 18778.0 1945.0 5183.5 10726.9 4289.5 5409.3 1909.8 1824.4 7406.7 1920.7 5418.1 5810.5 6963.2 4174.7 15671.4 3204.2 13620.4 1620.4 4244.5 3674.4 3985.7 2622.4 6104.2 10727.8 13879.3 3495.2 4452.8 2870.3 6024.9 6026.0 10017.9 6477.5 17539.6 10178.1 4280.9 6317.4 7166.3 5880.9 3051.9 4303.3 7137.5 3739.9 10744.5 2455.0 15099.8 2475.3 4245.7 1346.3 1650.5 1689.2 2678.1 1534.6 1712.3 1211.4 2550.5 1774.0 2220.6 2427.2 1828.9 1841.1 1470.9 1232.4 1223.2 78564.9 78683.9 71753.6 111983.3 73845.3 79126.1 94236.1 80705.7 87375.8 66562.7 82151.7 67597.2 4123.3 1487.2 1804.3 0.0 6867.9 2903.0 6184.5 4172.7 7102.6 0.0 4343.1 7054.0 183462.2 11539.8 3367.8 6422.4 0.0 0.0 6110.1 15211.0 1880.2 2059.0 908.9 7527.8 6522.7 7371.6 3995.8 17562.3 0.0 3405.9 0.0 6067.7 6569.9 13453.0 2064.3 20320.2 9969.1 26635.5 0.0 0.0 0.0 10468.7 2803.5 16148.3 2386.4 4627.8 7672.0 5539.3 2534.6 0.0 4773.4 0.0 4080.4 0.0 0.0 2818.6 9241.3 4966.1 7780.1 4657.8 24094.7 14129.0 3106.0 0.0 6304.4 11559.3 7641.7 5682.1 5225.7 5947.3 3034.9 0.0 6304.5 12298.1 10197.0 7899.3 MT-ATP8 "A6L, ATP8, MTATP8" ENSG00000228253 "Mitochondrially encoded ATP synthase membrane subunit 8" P03928 MT 8366-8572 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 350376.1" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 29301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 10572.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 10572.1" "Cell line enhanced" "Detected in all" "HeLa: 50977.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.54e-1)" "unprognostic (4.12e-2)" "unprognostic (3.95e-2)" "unprognostic (2.56e-1)" "unprognostic (3.07e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.56e-5)" "unprognostic (5.17e-2)" "unprognostic (6.61e-2)" "unprognostic (2.52e-3)" "unprognostic (8.26e-2)" "unprognostic (1.30e-2)" "unprognostic (1.10e-1)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (2.62e-1)" "unprognostic (1.63e-2)" 52547.2 73047.7 71006.2 6339.9 65385.6 4586.6 39961.9 63707.9 167507.6 15589.5 96812.2 53064.6 20904.2 18820.0 2108.9 28363.8 17245.1 3565.3 350376.1 65043.0 67794.6 122288.8 155197.7 20328.6 3668.3 79031.5 85769.3 16668.9 41045.8 34366.0 26028.4 5099.1 86389.3 39371.9 6765.3 18502.2 30660.9 4354.8 191901.6 34903.0 47114.2 2674.0 56399.9 20318.5 63822.8 22267.9 71449.8 4555.6 27150.4 93490.2 2399.0 29450.2 19789.6 61936.2 9856.9 3525.9 11216.6 2135.1 11962.8 1899.3 5504.5 19957.4 1175.7 896.0 1537.1 4090.3 6356.6 24786.3 4872.4 4328.0 3394.0 16426.4 706.7 6608.9 1397.3 11058.2 4500.9 18761.8 50977.1 9430.6 2174.3 11096.3 15424.0 4128.5 3403.9 1971.6 1680.6 12377.4 1285.7 9692.8 10174.9 7582.9 2738.5 5189.9 6492.1 16113.6 2467.4 5471.7 2512.1 5306.1 5447.4 5282.8 6499.8 9510.1 3516.6 6319.5 7567.6 6909.7 7767.4 17681.0 6781.8 22941.8 18909.8 4285.7 9562.3 9574.5 9412.0 5112.9 9201.9 14522.4 4225.0 18954.8 2666.9 10572.1 1775.5 2174.2 955.4 1388.5 1410.8 1767.9 1079.8 1154.3 992.0 1612.2 1301.2 1614.6 968.7 1526.5 1514.0 1189.7 924.2 673.4 71006.2 65385.6 63707.9 167507.6 65043.0 67794.6 79031.5 85769.3 86389.3 56399.9 71449.8 61936.2 76.9 189.1 178.7 0.0 1182.0 11.6 7.0 9.5 3775.0 0.0 104.1 150.4 29301.8 225.9 340.8 12.9 0.0 0.0 78.7 124.2 3.9 13.4 7.3 182.9 170.7 625.6 29.2 733.7 0.0 30.7 0.0 771.2 3726.9 282.0 295.9 161.6 219.2 729.6 0.0 0.0 0.0 59.9 0.0 344.8 8.0 42.1 40.7 539.8 12.4 0.0 23.5 0.0 21.6 0.0 0.0 20.3 98.8 25.2 1785.2 4.5 63.6 21.3 363.2 0.0 39.5 113.1 718.6 23.9 30.7 2607.0 9.1 0.0 731.3 62.3 52.8 6.7 MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 222644.8;heart muscle: 255389.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107039.5;Hepatocytes: 59794.3;Proximal enterocytes: 98329.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 54167.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB016241: AB_2229888, HPA069328: AB_2686122" "unprognostic (4.39e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "prognostic favorable (2.29e-4)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (1.20e-2)" "unprognostic (6.60e-2)" "unprognostic (2.83e-2)" "unprognostic (5.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-2)" 22006.8 46968.9 171347.0 8727.7 151652.8 11321.8 17952.5 132201.9 222644.8 10440.9 179120.2 42606.0 27505.7 11582.9 14226.0 20791.8 10700.5 11452.7 255389.3 151507.6 137459.2 63061.8 96575.5 12744.7 9111.4 176794.8 152802.2 8124.5 19467.4 41236.2 7420.2 10527.8 168465.9 12427.0 28389.7 12503.0 23260.1 17753.2 147209.5 26849.0 35366.3 13146.2 138626.1 16284.7 44852.9 10932.5 176888.2 7461.1 14056.3 184587.7 8381.2 17415.3 10559.7 131378.4 5837.6 8554.3 11384.1 12431.0 25510.2 11563.1 12037.2 12867.2 4284.9 3189.4 5257.4 10383.6 18320.5 15138.9 6040.7 9857.6 3118.2 21430.9 1326.6 11407.4 4515.1 7226.0 8040.6 9130.6 54167.9 19725.4 3521.2 5336.1 11055.5 13603.9 11589.8 3149.9 6917.5 14668.4 3902.1 8485.5 5916.3 10551.1 9525.6 14037.0 4378.4 23591.9 2905.0 7814.2 6900.5 5664.0 3401.6 9177.9 15910.6 15016.1 5414.7 7189.1 4466.7 17018.9 8305.7 13626.1 9809.7 17703.3 15637.8 12617.8 8438.9 12565.9 6642.1 4951.2 5072.9 3542.6 6235.7 13711.8 6294.4 5305.8 9759.2 3824.6 3085.1 4907.9 3420.5 5374.6 3047.3 3425.6 3444.6 5567.3 3080.8 3911.2 1900.4 3759.1 5775.1 4847.5 2947.7 3929.0 171347.0 151652.8 132201.9 222644.8 151507.6 137459.2 176794.8 152802.2 168465.9 138626.1 176888.2 131378.4 3924.0 2900.6 3897.1 0.0 13282.9 9769.7 9713.9 22625.0 20857.7 0.0 12033.2 11841.6 107039.5 30777.5 16135.4 19596.3 0.0 0.0 9288.4 40726.1 4255.4 7191.4 1555.3 13044.7 9033.9 7847.9 7514.7 45610.3 0.0 5089.4 0.0 6305.3 19235.7 25645.6 3832.6 20400.0 25951.4 59794.3 0.0 0.0 0.0 24302.1 19071.0 45533.4 7744.0 7398.4 11696.4 12124.7 6894.2 0.0 15180.0 0.0 8901.3 0.0 0.0 6410.5 23865.9 8490.1 13829.3 9441.3 98329.8 33652.6 10474.0 0.0 13614.6 11019.8 9403.5 12096.5 14338.7 27110.9 11475.1 0.0 11502.4 15179.6 27138.6 21770.7 MT-CO2 "CO2, COX2, MTCO2" ENSG00000198712 "Mitochondrially encoded cytochrome c oxidase II" P00403 MT 7586-8269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 164780.5;heart muscle: 210840.8" "Cell type enriched" "Detected in many" 13 "Cardiomyocytes: 709929.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 73985.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016243, HPA051505, HPA054758" Enhanced NA NA 240000 "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016243: AB_2066366, HPA051505: AB_2681511, HPA054758: AB_2682595" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (2.77e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (2.72e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.25e-1)" "unprognostic (9.30e-2)" "unprognostic (3.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.50e-2)" "unprognostic (3.72e-3)" 27287.7 50118.4 114427.0 5960.9 114629.6 9211.1 23112.5 102567.5 164780.5 8637.9 123709.0 47542.8 18239.3 10045.0 10813.1 24529.5 11015.1 5914.4 210840.8 108795.0 110116.5 112074.1 105449.6 14032.6 6314.3 129884.9 115346.3 7950.6 24515.9 29782.0 16861.9 10397.8 125082.8 25688.4 24989.1 8983.3 21379.6 12907.0 93258.6 22997.0 36121.9 9693.6 102620.8 18194.3 45409.4 14516.5 123032.8 6034.4 16877.7 109930.2 7889.2 21068.8 13184.5 102646.5 6276.2 9796.4 12777.6 12396.3 25548.5 9745.3 9393.2 7927.6 6429.8 4420.4 6584.3 10616.0 13681.5 12924.1 6467.6 11751.8 4522.1 23074.6 1724.1 16319.1 5925.8 10089.3 8726.0 9297.7 73985.8 20756.8 5543.0 7919.2 9987.0 14433.8 23568.7 2276.3 8072.8 14337.8 4979.3 12668.7 8862.9 12216.0 12212.6 13490.3 5804.8 22519.7 3353.4 12256.7 6160.6 5998.2 3899.6 10866.7 17578.2 17096.2 4758.2 7830.6 6527.3 15842.4 11881.3 18742.2 11084.6 31596.4 12345.0 10576.0 9043.3 10116.0 5740.6 6151.2 6563.0 7590.8 5638.0 15586.1 7129.7 20953.0 13541.7 15753.7 5586.8 8887.6 6782.0 11844.8 6189.5 6338.9 6316.7 10947.0 6386.1 7947.1 5329.9 6846.5 10055.3 8426.1 5367.4 7670.7 114427.0 114629.6 102567.5 164780.5 108795.0 110116.5 129884.9 115346.3 125082.8 102620.8 123032.8 102646.5 4337.7 1445.5 1999.8 0.0 11825.3 6754.0 8961.4 22171.6 22140.9 0.0 11994.6 16742.4 709929.9 18464.2 10323.3 18597.6 0.0 0.0 7569.1 29582.2 3709.5 3684.4 1119.7 12108.5 6979.9 16215.0 6396.9 27238.9 0.0 4873.7 0.0 10942.5 19089.4 20683.3 2144.6 17185.5 15141.7 53416.5 0.0 0.0 0.0 17158.1 14290.0 26774.7 4814.0 5284.9 7663.3 9292.7 5140.4 0.0 7967.0 0.0 6828.1 0.0 0.0 4709.1 15133.6 5123.0 14109.6 5949.4 40280.5 22569.2 7617.1 0.0 7060.4 9361.8 14171.2 7120.5 8965.1 26952.2 6702.8 0.0 8863.0 13639.8 19371.4 14261.8 MT-CO3 "CO3, COIII, COX3, MTCO3" ENSG00000198938 "Mitochondrially encoded cytochrome c oxidase III" P00414 MT 9207-9990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 189825.4;heart muscle: 231090.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 98114.9;Proximal enterocytes: 47697.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 47821.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042788 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042788: AB_10793985" "unprognostic (2.38e-1)" "unprognostic (5.24e-2)" "unprognostic (1.71e-1)" "unprognostic (1.88e-1)" "unprognostic (3.04e-1)" "unprognostic (2.93e-1)" "prognostic favorable (2.01e-4)" "unprognostic (1.18e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-2)" "prognostic favorable (1.04e-4)" "unprognostic (1.05e-1)" "unprognostic (8.80e-3)" "unprognostic (2.75e-2)" "unprognostic (1.20e-1)" "unprognostic (9.29e-2)" "unprognostic (1.33e-2)" 27612.7 53681.0 106768.6 6403.7 100201.0 11914.6 26962.2 92217.9 189825.4 9972.2 122787.3 41553.8 21299.6 10118.8 12166.4 23137.6 10414.1 8134.8 231090.6 101700.1 98402.0 135745.7 93934.0 11738.0 7309.6 111323.1 103274.0 9356.4 21307.1 30833.6 18098.1 9332.4 106050.0 25270.8 25404.7 14193.4 21229.0 16620.0 98348.0 28350.1 31017.2 10682.4 91790.3 14201.4 41772.3 19009.4 106894.6 5959.0 20136.7 138793.4 9366.6 19763.5 13535.9 91700.3 6374.2 7329.2 11033.5 15732.2 21484.7 8772.8 6020.3 8032.3 4753.9 3111.6 4736.6 9884.1 9176.0 14020.9 3392.6 6719.8 3380.0 16891.6 1769.9 9653.6 5455.7 4794.4 7644.1 7478.3 47821.5 16704.0 4327.8 4505.2 9419.7 8504.4 13400.6 3422.1 5046.7 10915.4 5848.3 7900.3 6047.2 13759.0 10367.7 12916.5 4589.9 25941.9 2461.0 9979.3 5226.1 4852.9 3482.9 10181.9 19232.2 10970.2 4917.9 6797.0 3741.8 4032.3 8135.9 15244.2 8471.0 19585.6 9432.2 5152.8 8782.1 9756.5 5388.8 5622.3 3881.6 8183.5 5151.5 14362.6 3475.8 2863.0 4714.1 2004.7 1562.3 1885.5 1896.8 2933.1 1703.2 1823.0 1927.4 3253.5 2137.7 2759.1 3629.6 2089.5 1920.3 1612.4 1186.9 2432.3 106768.6 100201.0 92217.9 189825.4 101700.1 98402.0 111323.1 103274.0 106050.0 91790.3 106894.6 91700.3 2817.9 1910.3 2767.0 0.0 9010.7 8343.8 9724.5 21550.3 14394.8 0.0 8643.0 8027.7 98114.9 20354.3 11786.8 16547.0 0.0 0.0 5698.3 25285.3 4368.9 5152.0 1929.0 10274.3 6922.4 7282.3 6805.3 29321.2 0.0 6670.2 0.0 5902.5 8605.1 22503.2 2090.9 20302.5 15810.3 44494.8 0.0 0.0 0.0 19209.5 11157.0 28166.3 5603.1 9286.2 11579.8 7637.7 5553.1 0.0 9746.7 0.0 6001.1 0.0 0.0 5901.3 16542.9 7809.0 8204.1 6813.7 47697.3 33390.3 6427.3 0.0 12142.0 15068.6 7967.9 11927.7 12469.2 17772.8 8480.1 0.0 7584.6 21335.3 22667.3 15127.4 MT-CYB "COB, CYTB, MTCYB, UQCR3" ENSG00000198727 "Mitochondrially encoded cytochrome b" P00156 MT 14747-15887 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Cataract, Deafness, Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 130283.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 87067.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 14365.7;HeLa: 18945.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032215, HPA068400, HPA074796" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB032215: AB_2261378, HPA068400: AB_2685982, HPA074796: " "unprognostic (4.50e-1)" "unprognostic (2.56e-1)" "unprognostic (9.12e-2)" "unprognostic (3.88e-2)" "unprognostic (9.22e-2)" "unprognostic (3.50e-1)" "prognostic favorable (5.96e-4)" "unprognostic (1.63e-2)" "unprognostic (8.53e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-3)" "unprognostic (6.09e-2)" "unprognostic (1.40e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (4.09e-2)" "unprognostic (1.54e-2)" 17885.7 25075.8 39972.4 2636.6 41108.8 2926.5 15122.5 36592.4 54341.4 6621.5 47885.4 19364.4 8941.2 7119.4 6555.4 10592.2 7498.6 3433.7 130283.4 39044.7 39534.1 60620.7 59133.6 6549.1 2529.8 46506.6 40032.7 6068.7 15418.7 9106.2 11552.0 5320.4 42841.1 15142.5 8793.2 8513.5 12205.1 7331.2 52625.7 13392.0 17520.7 5804.8 34579.6 7362.7 25263.2 7372.2 41908.6 1737.2 9758.2 63751.5 3582.0 12844.4 7620.0 35340.5 2322.4 3039.1 3687.6 3950.3 14365.7 2287.8 2963.8 2587.3 1076.5 668.0 1136.3 3013.8 4943.2 5840.7 1240.7 3087.3 794.6 7063.3 556.2 3180.7 1613.0 2880.4 2458.9 3277.0 18945.0 5461.7 2697.8 1862.5 3828.3 4981.3 4631.2 1257.6 2679.7 4457.1 1715.5 2341.4 1709.0 3565.6 3417.2 6354.8 1735.3 3789.4 824.1 2230.7 2036.7 2028.2 1449.8 3681.4 5134.1 5275.9 1308.0 2302.7 1802.1 3352.1 2587.4 5497.2 4911.1 6332.5 5398.3 2302.7 2984.2 4256.3 2037.2 972.6 1390.1 2557.4 1385.7 2822.6 1485.0 8811.6 3750.4 4806.7 1834.1 1738.1 2355.1 2806.2 2123.9 2376.2 1485.5 3034.9 2241.0 2781.9 2755.9 1680.5 1944.8 1468.0 1511.0 1612.6 39972.4 41108.8 36592.4 54341.4 39044.7 39534.1 46506.6 40032.7 42841.1 34579.6 41908.6 35340.5 3091.7 1185.9 1390.0 0.0 5710.5 3319.9 7605.2 9945.0 8512.3 0.0 4026.8 5510.1 87067.0 11564.1 5338.9 7470.6 0.0 0.0 3723.1 10971.1 2163.9 2555.0 789.7 9063.7 5550.2 5673.6 2863.2 16130.5 0.0 3523.1 0.0 4692.6 4895.1 15794.2 1889.0 16261.2 9871.2 17132.6 0.0 0.0 0.0 9502.4 5486.9 14290.0 2254.1 3983.1 7943.2 4269.6 2612.9 0.0 4118.1 0.0 2612.8 0.0 0.0 2977.1 8823.6 5402.0 5725.9 4425.8 25108.7 14736.3 4210.2 0.0 5798.2 9579.6 5914.9 4807.6 4136.3 9142.3 3422.9 0.0 5502.2 11093.2 10319.6 9796.7 MT-ND1 "MTND1, NAD1, ND1" ENSG00000198888 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1" P03886 MT 3307-4262 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Alzheimer disease, Amyloidosis, Diabetes mellitus, Disease variant, Epilepsy, FDA approved drug targets, Leber hereditary optic neuropathy, MELAS syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 111350.7;heart muscle: 127951.9" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 101184.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 9432.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 9432.2" "Cell line enhanced" "Detected in all" "HeLa: 28480.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033779, HPA066847" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB033779: AB_2149736, HPA066847: " "prognostic favorable (3.63e-4)" "unprognostic (3.55e-1)" "unprognostic (3.77e-2)" "unprognostic (3.65e-1)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.95e-3)" "unprognostic (5.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.26e-4)" "unprognostic (8.67e-2)" "unprognostic (8.66e-2)" "unprognostic (3.24e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-2)" "unprognostic (2.85e-2)" 19099.4 24937.1 77977.0 2682.9 79000.3 3456.4 17901.1 73833.1 111350.7 4652.6 82243.3 19464.4 6416.3 5929.7 6428.9 8365.1 6119.1 2846.9 127951.9 74131.5 81543.6 47946.3 45024.8 7877.3 2245.9 84675.5 84925.4 4636.3 15523.0 12519.5 7993.9 5163.4 88069.3 11358.6 8792.2 6455.8 11429.4 7047.3 69102.4 14504.0 16935.3 3849.2 68588.4 8228.4 26033.5 12223.4 81883.1 2158.8 7231.1 61460.4 2986.2 10333.3 5443.7 72626.3 3533.6 3499.2 2812.3 2571.1 10434.4 1879.8 3604.8 2946.1 872.8 805.7 835.0 6132.0 3710.1 4259.8 1831.7 2239.3 810.9 2285.7 316.3 1774.7 1592.0 3064.7 2432.6 4755.7 28480.4 8841.6 2231.9 2279.1 4495.2 4494.5 4734.4 1241.1 1773.2 3240.7 877.2 1226.5 2235.4 2580.5 2400.4 4813.7 1841.1 9325.6 757.8 2191.3 2603.6 1916.7 1277.6 2295.7 4312.3 5574.2 1165.0 1844.2 1632.5 2572.1 2943.6 3403.7 2306.2 7771.2 4632.1 2652.3 2396.0 3427.2 2511.3 2841.3 1883.7 2015.4 1784.6 3937.3 744.7 9432.2 1265.2 2347.3 512.4 662.6 732.0 1155.4 614.6 683.5 439.9 1185.3 800.8 960.2 3270.7 759.6 733.2 677.2 480.0 507.7 77977.0 79000.3 73833.1 111350.7 74131.5 81543.6 84675.5 84925.4 88069.3 68588.4 81883.1 72626.3 1754.9 1352.6 1511.3 0.0 3159.5 2265.8 3355.3 1632.2 2928.1 0.0 3174.3 3513.1 101184.9 9771.1 1985.3 4610.8 0.0 0.0 2175.7 12456.8 1033.1 1511.9 1087.5 3160.1 1985.1 4881.6 3135.6 8308.9 0.0 3595.1 0.0 2970.8 2347.6 5039.6 1402.2 7165.4 7745.2 16276.4 0.0 0.0 0.0 10835.1 927.7 12435.2 1651.4 5233.2 7049.5 2982.5 1497.7 0.0 4450.1 0.0 2385.2 0.0 0.0 2180.4 8080.9 3546.9 2046.0 3735.0 18353.7 8183.6 1760.8 0.0 6409.6 6534.6 4075.7 4806.0 5071.3 2061.1 2073.2 0.0 2839.0 4329.0 10735.4 5236.0 MT-ND2 "MTND2, NAD2, ND2" ENSG00000198763 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2" P03891 MT 4470-5511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Alzheimer disease, Amyloidosis, Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 101525.8;heart muscle: 130517.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 77734.8;Proximal enterocytes: 33797.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 16754.8" "Lineage enriched" "Detected in all" 10 "granulocytes: 16754.8" "Cell line enhanced" "Detected in all" "HeLa: 23544.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (5.82e-3)" "unprognostic (1.58e-2)" "unprognostic (1.53e-2)" "unprognostic (1.36e-1)" "unprognostic (4.77e-1)" "unprognostic (4.79e-2)" "unprognostic (9.56e-3)" "unprognostic (3.74e-2)" "unprognostic (2.18e-1)" "unprognostic (3.38e-3)" "unprognostic (4.55e-3)" "unprognostic (3.79e-2)" "unprognostic (4.35e-2)" "unprognostic (3.94e-2)" "unprognostic (2.11e-1)" "unprognostic (5.92e-2)" "unprognostic (4.35e-2)" 25741.8 33190.5 71860.8 2728.1 75185.8 2871.9 21730.1 67030.8 101525.8 7501.8 71811.2 22574.5 7339.4 7298.5 8093.3 11090.4 9270.8 2863.6 130517.4 67583.8 74656.1 57055.4 53965.1 9461.4 2469.7 81497.3 77858.3 7800.1 20642.6 9848.0 12388.5 5446.8 84069.6 17166.0 8141.9 5436.2 13468.5 5444.8 45903.7 15500.0 20333.4 3554.4 65578.7 8952.9 31183.1 11451.9 75256.7 2049.2 10704.5 50400.1 2830.9 14131.4 8428.2 66998.7 2964.9 3166.9 2774.5 4699.2 9795.6 1730.7 2618.5 2678.9 669.9 703.1 875.8 4014.2 3860.6 4185.9 2486.9 1936.7 1150.4 5147.5 444.4 3349.6 1504.2 3675.8 2270.9 4845.1 23544.1 6585.1 1999.7 4760.9 5392.4 2886.1 5969.8 1726.7 1692.0 2488.5 1049.4 2269.3 3606.2 3978.3 1701.5 3480.4 2711.2 7603.4 1396.2 3068.2 2045.4 2352.3 1554.8 3525.9 5071.4 4465.8 1728.4 2059.3 1159.0 3501.0 4372.7 4402.7 5412.1 5417.8 3333.0 2606.6 3230.5 3719.5 3483.2 2577.9 2356.8 3637.4 1695.0 4006.5 1196.1 16754.8 1658.1 2709.0 872.0 1066.1 1373.3 1568.7 1012.2 1099.7 632.5 1625.8 1212.2 1558.3 2355.9 1158.8 1341.7 1171.9 716.1 804.2 71860.8 75185.8 67030.8 101525.8 67583.8 74656.1 81497.3 77858.3 84069.6 65578.7 75256.7 66998.7 1855.6 919.9 759.8 0.0 3886.7 2666.7 7962.2 3116.2 2155.8 0.0 2560.5 3948.5 77734.8 10211.5 2425.9 6232.9 0.0 0.0 2313.0 13115.0 1807.8 1793.7 1314.5 4100.0 2322.6 4025.7 3175.3 10585.1 0.0 3677.8 0.0 2629.4 2366.5 5225.2 1865.9 7033.2 9394.0 19067.5 0.0 0.0 0.0 10974.6 1947.0 14566.9 1814.8 6327.6 9064.4 3148.2 1657.8 0.0 4768.9 0.0 3602.5 0.0 0.0 2565.3 9271.1 4538.8 1959.6 4228.6 33797.5 12714.8 3449.0 0.0 7283.9 6341.5 3547.2 5465.6 4872.6 1826.5 2455.7 0.0 3694.7 2538.3 10272.4 7385.5 MT-ND3 "MTND3, NAD3, ND3" ENSG00000198840 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3" P03897 MT 10059-10404 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 184151.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37883.1;Proximal enterocytes: 23257.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 23280.2;HeLa: 21694.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063296 Enhanced Uncertain Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA063296: AB_2684978" "unprognostic (1.71e-2)" "unprognostic (1.05e-1)" "unprognostic (8.10e-2)" "unprognostic (3.07e-1)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "prognostic favorable (4.63e-5)" "unprognostic (2.45e-2)" "unprognostic (7.13e-2)" "unprognostic (8.85e-2)" "unprognostic (1.76e-3)" "unprognostic (1.74e-1)" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (1.19e-1)" "unprognostic (2.07e-1)" "unprognostic (5.65e-3)" 31356.6 42036.1 79316.1 3483.1 80070.8 4077.5 25368.6 75454.6 124729.8 8985.8 81148.8 26406.1 11478.9 8410.1 8217.8 12712.6 10495.3 3610.0 184151.1 75602.8 85299.8 84244.0 72988.4 9018.3 3610.8 89729.0 83678.9 9439.2 26008.9 14199.5 13387.4 6281.1 85648.8 23996.0 10095.2 6318.4 14787.5 8355.4 70313.2 16879.7 21792.1 4960.7 71704.7 11407.9 36122.2 10815.9 84470.1 3654.8 14626.9 73367.5 3934.1 18841.5 10373.7 74059.9 3324.0 5255.7 3450.6 3399.1 23280.2 4613.0 2871.7 2717.2 1592.1 1441.9 1616.6 7973.2 5004.1 3408.8 4095.7 3519.2 2600.2 6710.1 1504.4 5941.5 2461.9 4945.3 7153.7 3371.4 21694.2 13369.3 3629.0 5018.8 4874.1 8076.0 10704.2 2416.7 2704.4 8547.3 2285.4 3853.4 2711.1 3864.5 2747.1 10748.2 2646.2 6609.3 1779.4 9407.1 4824.1 2262.5 3389.7 3164.0 8729.4 8962.3 1417.0 3058.9 1310.8 2587.7 5763.8 8928.3 6011.6 7960.5 3898.6 2207.0 3378.3 3876.8 2982.9 1492.1 2128.5 7735.7 1794.0 2976.6 1284.1 2263.7 612.4 386.5 336.6 346.8 441.9 672.5 393.0 417.4 321.5 686.4 568.4 769.3 968.2 447.0 335.5 312.1 262.5 353.1 79316.1 80070.8 75454.6 124729.8 75602.8 85299.8 89729.0 83678.9 85648.8 71704.7 84470.1 74059.9 4254.0 701.9 879.1 0.0 6320.6 1987.5 2507.9 1722.8 5384.4 0.0 3350.4 5821.1 37883.1 9781.1 1560.8 5041.1 0.0 0.0 5039.9 14324.8 1164.1 1320.8 1023.5 11751.2 6030.4 3302.6 2852.4 14390.0 0.0 2870.2 0.0 3063.4 6039.9 17552.8 1453.7 17373.9 10407.8 20920.6 0.0 0.0 0.0 11328.3 870.8 16584.4 1757.6 5643.0 9133.7 4877.6 1858.7 0.0 4964.0 0.0 2775.5 0.0 0.0 2194.1 9034.9 4865.3 6343.6 1554.6 23257.1 8457.2 2113.9 0.0 7001.2 6561.9 3856.1 5442.6 3706.2 3801.0 1888.8 0.0 4844.1 3423.5 10381.8 2314.6 MT-ND4 "LHON, MTND4, NAD4, ND4" ENSG00000198886 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4" P03905 MT 10760-12137 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 196536.0" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 253563.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13456.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 41594.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053928 Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA053928: AB_2682313" "unprognostic (8.39e-2)" "unprognostic (1.83e-1)" "unprognostic (7.29e-2)" "unprognostic (9.54e-2)" "unprognostic (5.41e-2)" "unprognostic (3.78e-2)" "unprognostic (2.50e-3)" "unprognostic (8.16e-2)" "unprognostic (1.45e-1)" "prognostic favorable (1.76e-4)" "unprognostic (1.01e-2)" "unprognostic (7.23e-2)" "unprognostic (2.79e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (3.14e-2)" "unprognostic (4.24e-2)" 23701.9 43566.1 86386.5 4193.8 83474.8 3652.7 19363.5 76852.9 119139.4 8711.6 100909.6 30312.4 11021.5 10764.3 6795.9 15885.7 10624.6 4622.9 196536.0 81116.7 85290.4 76204.1 101401.1 11855.8 3820.4 102081.7 90689.2 8957.6 21476.2 15709.9 12834.3 7692.4 97098.9 22214.5 15007.9 14112.1 17508.5 11691.2 61489.1 18268.8 25046.6 7116.7 75024.9 12782.7 39594.1 13571.1 91494.4 3233.7 14785.3 70605.7 4913.1 19417.4 10309.3 74806.7 4251.7 4285.9 5449.6 8075.1 12523.6 3123.1 3808.6 4184.0 1603.2 958.4 1834.2 6555.4 4688.4 7428.4 3608.7 3590.8 1396.3 7685.0 496.1 6777.9 1691.7 4330.2 2654.6 4592.7 41594.9 11166.3 1884.9 4672.8 5223.9 5330.2 7007.6 1403.3 4977.9 8925.4 2344.4 3683.1 3908.9 8930.2 3461.9 9508.0 1848.1 10481.0 1551.2 3650.3 2876.4 2481.0 1712.1 4518.2 6770.1 8938.3 1999.0 2694.8 2434.3 7967.3 4267.8 9600.3 5601.2 10888.7 6532.2 3851.7 3726.9 5232.7 3330.8 5307.6 2292.6 3407.7 2514.1 7881.4 2100.8 13456.8 3334.1 7103.1 1902.0 2192.8 2614.3 3555.5 2129.5 2285.7 1616.0 3624.4 2452.9 3095.1 2513.1 2106.5 2329.2 2112.6 1668.2 1840.0 86386.5 83474.8 76852.9 119139.4 81116.7 85290.4 102081.7 90689.2 97098.9 75024.9 91494.4 74806.7 3065.0 1269.2 1516.1 0.0 6183.3 4404.5 9073.3 7719.8 2713.0 0.0 6210.4 6965.6 253563.4 15377.3 4975.3 12806.1 0.0 0.0 4005.7 20185.0 2435.8 2924.2 1109.7 6731.7 4298.6 9316.2 5090.0 20898.0 0.0 4058.3 0.0 5843.3 5601.5 11920.4 2188.6 15486.9 13931.3 35046.7 0.0 0.0 0.0 14557.8 5771.7 22254.8 3452.7 5132.5 8834.9 4749.3 3799.3 0.0 6280.7 0.0 4212.2 0.0 0.0 3710.0 12363.2 5788.3 3409.4 5872.9 28978.7 17714.1 4527.9 0.0 6310.9 8264.3 7732.9 6461.4 6003.0 3008.8 4937.6 0.0 5125.3 7671.5 15595.2 11405.7 MT-ND4L "MTND4L, NAD4L, ND4L" ENSG00000212907 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L" P03901 MT 10470-10766 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 132930.7;heart muscle: 145078.7" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 30444.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 50775.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075648 Approved Centrosome,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Centrosome "HPA075648: AB_2686760" "unprognostic (5.81e-2)" "unprognostic (3.46e-2)" "unprognostic (2.76e-2)" "unprognostic (7.91e-2)" "unprognostic (5.64e-2)" "unprognostic (1.05e-1)" "prognostic favorable (4.47e-4)" "unprognostic (1.97e-1)" "unprognostic (4.04e-2)" "unprognostic (4.63e-3)" "unprognostic (6.61e-2)" "unprognostic (7.38e-3)" "unprognostic (1.39e-1)" "unprognostic (3.09e-1)" "unprognostic (3.73e-1)" "unprognostic (2.97e-2)" "unprognostic (5.68e-2)" 20104.7 29874.0 85794.9 4122.5 86270.4 3115.3 14930.3 82985.5 132930.7 6880.0 93989.2 20616.6 9025.8 7679.7 5976.7 10820.3 7752.4 4365.8 145078.7 84214.9 90415.7 46912.7 74928.5 8462.2 2787.1 92948.1 87984.2 6729.2 16038.2 20410.6 9234.3 5840.3 89012.2 16438.2 14044.5 15747.5 12913.6 12715.8 58998.5 13345.9 17015.9 6979.3 79192.1 7285.6 28192.3 9561.4 87700.1 4435.4 11270.7 103082.4 4852.1 15113.7 7437.4 83632.8 4598.0 4121.5 7308.1 7468.2 25088.0 5217.1 3223.3 9523.0 2384.3 1468.4 2651.9 6894.3 4080.7 11229.9 3809.7 6497.0 2387.4 8496.5 1155.8 10210.3 2895.1 4454.2 4711.8 8095.9 50775.4 13024.1 3671.8 8429.4 6965.0 9229.0 10159.4 2792.9 9675.2 10923.1 2983.6 5697.7 4556.7 7771.2 5412.1 8124.5 3199.8 10639.4 1846.3 4811.8 4953.4 1842.5 3155.8 5025.1 7636.0 9464.9 2208.4 2971.3 4666.2 7283.7 3197.8 15599.0 5199.9 10420.1 9592.2 3792.1 4708.5 5630.1 3738.0 6985.1 3552.9 6053.5 2725.1 11018.8 1816.1 16170.2 4327.0 8286.8 2536.0 2849.6 3435.6 4233.2 2723.9 2939.9 2282.7 4618.7 3206.8 4006.1 2010.3 2906.4 2817.9 2884.1 2096.4 2551.4 85794.9 86270.4 82985.5 132930.7 84214.9 90415.7 92948.1 87984.2 89012.2 79192.1 87700.1 83632.8 503.6 224.4 217.6 0.0 2303.6 228.5 254.2 170.4 5991.6 0.0 764.0 886.3 30444.3 1464.1 438.4 323.7 0.0 0.0 449.8 1428.3 90.1 152.9 52.8 870.1 618.8 942.3 256.6 3302.0 0.0 342.2 0.0 1129.2 5335.9 1186.3 479.3 1394.0 1520.3 4413.7 0.0 0.0 0.0 727.8 99.7 1977.9 193.5 286.1 417.2 1043.8 256.1 0.0 312.9 0.0 133.9 0.0 0.0 284.5 867.0 230.9 4395.8 129.7 1228.2 589.4 582.7 0.0 348.4 711.2 1052.8 247.0 207.4 5256.4 242.2 0.0 1387.0 308.6 573.4 207.9 MT-ND5 "MTND5, NAD5, ND5" ENSG00000198786 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5" P03915 MT 12337-14148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 25147.7;heart muscle: 26116.9;skeletal muscle: 25697.4" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 35040.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 10198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.87e-1)" "unprognostic (3.18e-2)" "unprognostic (3.00e-1)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-3)" "unprognostic (5.09e-3)" "unprognostic (1.06e-2)" "unprognostic (3.01e-1)" "unprognostic (3.29e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.31e-5)" "unprognostic (9.93e-3)" "unprognostic (8.75e-2)" "unprognostic (1.26e-2)" "unprognostic (3.68e-2)" 5288.6 4777.7 18907.8 1742.2 18307.4 1525.5 2456.7 14400.2 21432.3 1614.3 22368.1 4280.6 4135.2 1972.7 2508.1 2717.8 3030.2 2040.5 26116.9 16370.1 20521.2 8014.5 10041.3 2683.6 1180.6 25147.7 20794.2 1886.3 2631.6 4813.1 1528.8 1691.5 23065.0 2812.7 2879.0 3264.8 2819.2 2163.8 25697.4 6657.3 4780.7 2643.7 13881.7 2014.4 6673.9 1678.5 21024.6 794.7 2059.1 19444.2 1541.4 3557.5 1537.7 13870.1 1615.8 1671.5 1998.7 1937.9 5903.9 1530.3 1075.8 3208.3 492.5 355.1 583.1 2472.6 2051.0 3865.3 1590.5 1510.4 397.3 3350.6 191.2 1685.7 583.4 2182.3 1281.4 2840.4 10198.2 4239.2 678.8 2010.7 2824.3 2305.4 1315.5 401.6 951.8 1933.5 725.2 1233.3 1056.8 1794.8 1216.3 3046.1 757.3 2453.4 397.5 910.2 903.0 1432.9 938.2 1668.7 2083.2 3132.2 595.0 904.1 1496.1 2636.3 894.4 3001.9 1927.1 2979.2 5094.9 2013.2 1403.2 2409.7 1271.9 678.8 1246.0 1066.9 1077.4 1780.4 897.7 2851.8 1521.7 874.2 771.4 980.3 922.8 979.1 753.9 839.2 746.5 1096.6 729.2 869.0 446.2 785.1 1039.5 890.3 628.6 492.0 18907.8 18307.4 14400.2 21432.3 16370.1 20521.2 25147.7 20794.2 23065.0 13881.7 21024.6 13870.1 773.3 628.2 594.2 0.0 1707.9 895.1 1050.1 1005.5 3261.6 0.0 1003.4 1025.1 35040.8 2566.4 934.5 1156.8 0.0 0.0 977.0 3181.2 283.7 804.1 109.5 3130.4 2025.6 1614.3 782.9 3776.6 0.0 936.6 0.0 1437.2 3609.6 5212.8 862.1 2987.5 2623.3 6597.7 0.0 0.0 0.0 1776.8 583.9 3664.2 661.9 528.9 1057.5 1364.5 608.3 0.0 1303.9 0.0 756.0 0.0 0.0 1327.8 2211.7 848.6 2674.2 753.3 4484.5 2410.8 1282.0 0.0 696.8 1941.5 1558.6 652.2 521.9 3002.4 973.6 0.0 1527.8 1560.9 1650.5 1506.6 MT-ND6 "MTND6, NAD6, ND6" ENSG00000198695 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6" P03923 MT 14149-14673 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 35802.7;skeletal muscle: 57879.2" "Cell type enriched" "Detected in many" 13 "Cardiomyocytes: 15756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 20826.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.96e-1)" "unprognostic (3.27e-1)" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.03e-3)" "unprognostic (6.02e-3)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (6.06e-3)" "unprognostic (2.91e-1)" "prognostic favorable (8.91e-6)" "unprognostic (3.64e-2)" "unprognostic (1.42e-2)" "unprognostic (1.15e-2)" "unprognostic (2.92e-2)" 7945.8 6310.2 5769.7 3186.7 3927.7 3253.0 3096.2 2199.5 5682.5 2191.3 13970.3 6452.8 7840.8 3145.2 54.5 5822.6 5447.4 3433.9 35802.7 4361.1 7820.0 9569.5 11697.0 4598.5 2503.1 13167.2 11029.3 2126.9 4152.4 69.3 1372.8 953.0 13713.7 2509.5 97.7 4313.6 4084.0 40.6 57879.2 15225.1 8006.6 51.8 1229.7 4205.8 10030.4 1993.1 8318.4 40.9 2562.5 243.6 43.1 5236.3 1897.2 1060.7 3305.7 2595.3 2255.7 2869.4 371.0 34.6 1614.6 4329.1 8.9 13.9 14.2 3553.8 3233.4 6999.5 2873.3 117.5 423.7 4781.1 25.1 79.1 23.3 4178.5 1966.3 4217.6 20826.9 10361.0 29.7 2704.1 3805.1 64.4 103.3 103.9 86.4 2123.1 23.2 1445.3 1855.2 2671.0 94.5 6976.5 836.0 3680.9 492.5 1868.7 1267.3 2002.7 1440.3 3034.3 60.9 9493.6 926.2 1476.3 2250.2 3898.6 1876.3 3559.0 3037.2 5182.3 8822.6 2473.6 2088.6 3550.5 1766.8 906.6 2600.9 1705.0 1682.9 2680.8 1473.8 2089.0 1092.3 645.1 733.4 881.5 840.2 1047.3 776.1 800.0 582.8 1016.1 760.2 870.6 453.3 752.2 963.0 790.6 635.2 365.4 5769.7 3927.7 2199.5 5682.5 4361.1 7820.0 13167.2 11029.3 13713.7 1229.7 8318.4 1060.7 31.2 83.3 62.2 0.0 328.4 16.8 55.8 75.1 1210.0 0.0 52.2 31.2 15756.5 273.1 107.1 128.8 0.0 0.0 78.9 125.6 17.6 32.6 8.2 154.1 132.5 478.6 30.1 797.7 0.0 35.3 0.0 396.2 886.9 247.7 98.0 130.6 385.8 699.5 0.0 0.0 0.0 59.8 44.7 518.3 20.1 33.4 62.4 214.3 33.8 0.0 66.3 0.0 48.4 0.0 0.0 25.6 69.9 45.1 1055.4 152.0 76.1 175.7 111.0 0.0 59.2 121.6 423.9 31.7 60.5 1160.0 20.5 0.0 266.3 58.1 78.4 117.0 MTERF3 "CGI-12, FLJ10939, MTERFD1" ENSG00000156469 "Mitochondrial transcription termination factor 3" Q96E29 8 96239398-96261610 "Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007355 Supported Mitochondria,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA007355: " "unprognostic (4.08e-2)" "unprognostic (1.46e-1)" "unprognostic (4.68e-2)" "unprognostic (2.31e-2)" "unprognostic (3.86e-2)" "unprognostic (6.66e-2)" "unprognostic (2.75e-3)" "unprognostic (3.11e-3)" "unprognostic (6.43e-2)" "unprognostic (2.00e-1)" "unprognostic (3.84e-2)" "unprognostic (8.56e-2)" "prognostic unfavorable (5.88e-5)" "unprognostic (8.67e-3)" "unprognostic (8.81e-2)" "unprognostic (2.27e-1)" "unprognostic (1.74e-3)" 15.0 16.3 16.3 15.3 16.9 11.5 17.9 18.6 21.8 14.0 20.9 14.7 12.6 13.5 22.9 11.6 12.7 12.4 27.8 16.1 17.3 18.3 23.1 12.1 18.2 16.4 16.3 12.1 15.5 22.3 12.6 16.7 17.2 13.5 14.4 16.0 12.9 17.2 30.2 17.0 11.5 16.6 15.9 16.0 12.7 11.8 16.6 16.7 11.9 38.2 19.4 16.4 12.0 17.8 41.1 25.9 38.1 30.3 26.4 27.4 17.5 30.8 25.0 43.9 44.2 18.8 29.6 36.5 63.3 18.2 22.5 22.8 39.7 24.1 53.2 35.6 29.3 52.5 20.6 22.8 37.1 17.9 20.7 27.5 35.4 35.6 33.5 22.9 36.5 39.0 45.1 18.7 44.7 26.9 76.6 52.8 19.8 71.6 39.8 45.9 31.2 28.8 32.7 21.8 25.9 20.4 23.0 6.6 33.8 24.5 34.3 25.0 16.3 30.9 20.8 36.0 27.7 21.3 28.9 43.2 33.4 47.3 41.3 39.5 13.4 6.1 15.6 15.9 22.6 20.4 17.7 17.8 20.2 17.7 19.8 20.2 2.2 23.8 15.8 24.3 18.6 10.1 16.3 16.9 18.6 21.8 16.1 17.3 16.4 16.3 17.2 15.9 16.6 17.8 10.4 3.2 6.9 7.8 10.8 0.0 21.2 0.0 10.8 0.0 6.6 8.5 31.2 5.7 5.6 5.5 0.0 30.4 10.8 0.9 13.7 12.5 5.6 6.2 10.1 8.1 0.0 12.4 12.9 9.8 21.0 12.7 4.1 5.4 6.3 11.2 6.1 8.0 16.2 0.0 12.6 3.6 0.0 5.2 0.0 4.1 13.7 7.1 0.0 4.7 16.0 0.0 15.5 7.5 14.2 7.7 3.3 13.9 7.0 22.9 3.3 11.1 5.1 0.0 13.1 10.3 9.9 28.2 21.2 9.1 0.0 17.4 8.8 9.5 5.3 11.7 MTFR1L FAM54B ENSG00000117640 "Mitochondrial fission regulator 1 like" Q9H019 1 25818640-25832942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 161.1;Early spermatids: 216.1;Late spermatids: 590.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027124, HPA027130" Approved Approved "Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Cell Junctions" "HPA027124: AB_10600211, HPA027130: AB_10611251" "unprognostic (9.90e-2)" "unprognostic (6.86e-3)" "unprognostic (9.29e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.52e-3)" "unprognostic (2.12e-1)" "unprognostic (2.24e-1)" "unprognostic (9.89e-3)" "unprognostic (5.33e-2)" "prognostic favorable (5.89e-12)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.69e-1)" "unprognostic (1.33e-1)" 39.0 138.0 79.6 22.2 82.8 17.8 37.4 80.0 88.4 51.0 84.6 74.1 46.8 51.0 57.8 39.4 44.9 32.7 169.1 81.7 81.3 71.7 91.3 32.4 25.8 80.2 83.8 68.4 46.0 106.0 51.6 40.7 79.6 55.8 37.3 62.1 43.3 70.1 221.8 35.6 46.9 50.0 78.6 44.2 56.6 82.5 83.2 24.7 48.1 239.7 26.3 58.3 40.5 78.5 19.5 26.7 53.2 53.6 67.6 63.8 22.2 44.7 63.7 45.2 49.9 8.7 39.7 6.6 38.9 80.1 40.0 17.4 44.1 38.6 44.8 43.9 39.8 55.6 44.3 35.9 64.6 45.5 52.9 65.3 36.4 48.3 36.1 67.0 37.9 27.0 34.7 29.2 66.1 21.6 26.3 33.6 29.4 26.0 39.4 26.0 47.4 19.8 47.1 18.3 53.6 48.5 33.6 32.4 67.8 35.8 26.7 43.1 38.6 36.7 28.9 86.6 28.5 30.5 19.3 23.2 63.6 62.5 41.2 71.7 50.5 111.7 25.7 50.8 15.6 28.1 24.1 22.9 55.0 28.8 25.4 23.1 13.6 27.6 58.3 22.7 27.3 51.1 79.6 82.8 80.0 88.4 81.7 81.3 80.2 83.8 79.6 78.6 83.2 78.5 18.7 16.0 24.5 24.2 14.1 13.5 20.8 38.6 25.0 0.0 21.6 23.6 161.1 25.8 21.7 22.0 0.0 55.9 14.8 15.7 103.7 32.4 216.1 11.3 16.7 17.1 15.6 12.4 18.2 33.5 36.7 28.4 21.4 10.6 36.1 21.9 21.4 35.5 34.9 0.0 24.1 14.9 34.6 15.1 17.3 590.4 34.2 25.6 44.4 6.5 43.5 0.0 12.3 12.5 15.2 27.7 15.0 39.1 15.4 16.2 39.3 70.6 10.5 0.0 26.3 23.3 31.3 144.7 49.9 15.4 12.9 59.4 13.1 29.8 18.0 16.5 MTIF3 "IF-3mt, IF3(mt)" ENSG00000122033 "Mitochondrial translational initiation factor 3" Q9H2K0 13 27435643-27450591 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 610.0;Proximal tubular cells: 475.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039791 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA039791: AB_10795296" "unprognostic (1.82e-1)" "unprognostic (1.44e-2)" "unprognostic (2.59e-1)" "unprognostic (3.26e-3)" "unprognostic (1.49e-2)" "unprognostic (8.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (3.77e-1)" "unprognostic (1.64e-2)" "unprognostic (1.62e-1)" "unprognostic (2.40e-1)" "unprognostic (3.24e-2)" "unprognostic (1.13e-1)" "unprognostic (9.27e-2)" "prognostic favorable (8.41e-4)" 61.8 55.0 59.5 29.2 59.8 17.1 51.0 61.0 93.4 36.7 60.4 46.7 42.8 28.4 67.1 39.9 30.4 37.0 133.4 59.0 61.7 63.1 65.5 29.2 44.5 60.9 60.2 37.1 54.4 43.4 50.8 30.9 60.9 45.3 44.6 74.7 82.9 43.9 90.8 39.9 41.8 30.5 58.8 49.6 48.1 61.8 60.6 47.3 36.9 109.8 46.1 36.7 34.0 62.0 29.9 21.9 48.5 23.5 53.2 78.8 22.6 44.0 51.1 33.8 33.8 28.3 37.5 33.3 28.4 50.8 22.8 25.1 27.2 37.1 46.3 34.3 31.2 42.6 19.1 36.7 52.2 43.8 38.8 44.6 65.5 27.7 35.1 75.6 60.0 33.8 24.0 13.6 51.2 54.0 39.7 54.2 24.4 100.1 24.0 22.8 24.3 37.5 69.8 31.3 32.9 20.6 28.4 39.1 50.7 51.8 31.3 62.5 38.1 21.4 12.5 56.1 29.5 10.0 14.9 19.1 21.5 44.3 31.1 85.8 53.0 75.4 30.8 51.2 32.9 49.1 38.9 31.1 55.2 42.8 34.0 35.2 36.5 37.2 48.3 88.2 47.4 41.3 59.5 59.8 61.0 93.4 59.0 61.7 60.9 60.2 60.9 58.8 60.6 62.0 88.5 28.9 47.4 29.0 74.0 34.0 34.0 103.9 43.9 0.0 91.6 95.4 179.1 87.2 76.3 115.8 0.0 102.6 60.4 102.2 326.8 89.6 610.0 93.7 63.4 70.3 64.1 59.7 22.8 104.1 67.0 62.7 47.4 74.5 71.7 50.6 79.9 223.0 102.3 0.0 26.4 112.8 103.7 114.8 50.2 283.4 139.8 67.7 106.7 24.4 106.4 0.0 80.3 30.7 43.7 98.3 108.8 124.8 71.1 43.7 142.8 475.5 83.2 0.0 124.9 48.8 69.2 243.6 87.6 62.8 42.5 56.8 58.5 69.6 96.8 44.8 MTRES1 "C6orf203, HSPC230, PRED31" ENSG00000130349 "Mitochondrial transcription rescue factor 1" Q9P0P8 6 107028199-107051586 "Predicted intracellular proteins" "Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 47.4;Cytotrophoblasts: 31.6;Extravillous trophoblasts: 14.3;Hofbauer cells: 24.3;Syncytiotrophoblasts: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049535 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "HPA049535: AB_2680808" "unprognostic (1.34e-3)" "unprognostic (9.38e-2)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (8.11e-2)" "unprognostic (2.71e-2)" "unprognostic (3.44e-2)" "unprognostic (1.89e-2)" "unprognostic (4.24e-2)" "unprognostic (1.05e-2)" "prognostic favorable (3.29e-4)" "unprognostic (2.28e-1)" "prognostic favorable (4.09e-5)" "unprognostic (2.64e-1)" "unprognostic (9.98e-2)" "unprognostic (3.19e-2)" "prognostic favorable (2.11e-5)" 14.5 33.1 22.3 8.8 22.6 5.6 12.5 23.9 35.7 11.0 24.7 19.6 17.4 11.4 19.0 14.7 11.1 8.2 33.9 22.2 23.3 25.1 28.7 7.9 11.3 22.2 22.6 11.2 13.7 14.0 12.1 8.8 22.0 11.1 17.8 12.3 16.1 11.7 41.8 10.8 14.8 10.1 22.1 13.1 15.4 9.5 22.4 10.4 16.3 36.8 12.2 13.3 11.4 23.1 11.6 7.1 21.5 30.5 39.1 33.6 8.9 24.1 19.1 15.7 20.2 4.6 8.7 31.8 17.6 17.5 17.2 16.1 15.4 20.9 21.6 25.9 11.5 19.5 7.0 7.7 26.0 23.0 10.2 24.3 29.2 13.6 19.6 21.1 22.3 24.5 22.7 23.8 33.5 15.9 10.5 34.3 10.3 36.9 12.0 19.0 17.8 14.7 41.0 16.2 13.6 14.1 11.9 15.6 22.5 16.0 12.6 40.7 17.4 10.6 10.3 13.4 13.0 5.0 7.8 17.2 18.5 35.6 22.7 1.4 14.9 14.2 16.0 15.9 16.7 20.6 18.4 17.8 21.1 19.6 25.0 21.8 1.7 20.3 14.6 21.0 26.5 13.6 22.3 22.6 23.9 35.7 22.2 23.3 22.2 22.6 22.0 22.1 22.4 23.1 2.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.0 31.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 14.3 5.6 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 18.2 0.2 0.0 0.0 0.0 MTRF1L "HMRF1L, mtRF1a" ENSG00000112031 "Mitochondrial translational release factor 1 like" Q9UGC7 6 152987362-153002709 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036367 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" "HPA036367: AB_10670715" "prognostic unfavorable (4.82e-4)" "unprognostic (4.64e-2)" "unprognostic (1.65e-2)" "unprognostic (3.56e-3)" "unprognostic (4.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.01e-3)" "unprognostic (4.80e-3)" "unprognostic (2.88e-1)" "unprognostic (3.82e-2)" "unprognostic (8.82e-2)" "unprognostic (3.61e-2)" "unprognostic (1.97e-1)" "unprognostic (7.46e-3)" "unprognostic (1.91e-1)" "unprognostic (2.61e-2)" "unprognostic (4.84e-1)" 6.8 6.2 8.4 5.8 10.3 7.1 4.6 12.6 10.3 4.8 13.0 7.6 8.2 4.0 5.9 5.4 3.6 5.1 11.4 8.3 9.6 10.1 7.7 4.6 6.6 9.7 9.5 4.2 6.2 8.6 3.8 5.5 11.0 5.1 6.2 10.3 5.5 5.5 17.9 7.7 6.2 6.7 9.4 5.4 5.7 4.6 9.7 4.8 7.6 21.9 5.8 6.0 3.5 10.7 7.8 8.9 14.8 20.4 16.1 8.5 14.7 13.9 13.4 12.8 18.6 15.4 6.1 14.0 10.7 14.3 22.0 11.7 21.3 12.3 18.5 16.0 14.7 14.0 12.8 20.9 13.9 14.3 14.4 13.4 14.1 16.2 17.9 12.4 18.4 15.3 22.4 8.8 15.4 12.8 10.8 12.1 8.9 17.2 13.1 10.3 11.0 11.2 19.2 13.7 15.6 19.6 18.1 12.9 10.3 16.4 8.6 15.6 12.8 10.2 16.3 17.3 18.2 15.6 15.7 14.8 19.6 10.7 13.1 10.3 3.5 7.1 3.2 5.2 2.8 3.3 3.4 2.9 3.7 2.4 3.1 3.5 3.4 3.3 6.9 2.7 4.0 4.0 8.4 10.3 12.6 10.3 8.3 9.6 9.7 9.5 11.0 9.4 9.7 10.7 29.9 12.8 16.4 11.8 19.9 33.9 24.2 14.5 20.5 0.0 13.8 11.4 28.0 8.6 13.7 18.4 0.0 15.7 15.7 26.3 25.4 34.1 59.8 15.2 22.8 34.5 17.3 14.9 13.0 26.7 24.3 23.6 14.3 20.3 18.4 17.7 62.8 17.6 17.1 0.0 13.2 12.9 12.2 21.2 15.4 54.5 20.2 23.5 16.0 9.4 31.2 0.0 21.6 11.1 11.8 34.0 22.9 25.6 24.0 21.2 27.9 39.2 6.8 0.0 39.5 23.7 30.0 43.4 13.8 29.1 32.7 19.7 16.5 33.8 17.9 23.4 MTX2 ENSG00000128654 "Metaxin 2" O75431 2 176269395-176338025 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 201.5;Spermatocytes: 247.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031550, HPA031551, HPA031552" Approved Approved Supported Nucleoli,Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria Nucleoli "HPA031550: AB_10599733, HPA031551: AB_10601442, HPA031552: AB_10794616" "unprognostic (2.61e-1)" "unprognostic (9.86e-2)" "unprognostic (6.54e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "unprognostic (2.87e-2)" "unprognostic (3.97e-2)" "unprognostic (1.80e-2)" "unprognostic (8.30e-2)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (9.92e-2)" "unprognostic (3.15e-2)" "unprognostic (1.33e-2)" 20.4 37.4 31.8 15.2 33.6 9.2 27.0 32.8 46.7 22.1 35.9 31.2 22.8 18.7 39.3 38.1 28.9 14.5 49.8 33.3 34.4 46.4 30.8 15.6 14.2 33.9 32.0 21.1 26.3 48.1 29.5 25.8 33.2 26.4 35.5 47.3 20.4 22.6 74.4 23.4 20.2 25.7 34.0 15.6 24.4 64.3 33.5 18.2 20.4 70.9 20.8 25.1 24.7 35.6 52.2 31.0 60.8 37.8 40.0 45.9 58.3 54.5 52.0 49.8 58.3 53.1 55.8 66.4 91.4 49.1 79.9 34.5 67.1 67.6 67.9 66.6 49.4 63.9 39.1 94.9 62.7 98.9 20.7 51.1 83.5 52.2 89.1 60.3 72.0 64.3 86.8 50.2 59.6 47.4 34.9 102.9 58.3 101.8 45.5 0.0 44.0 60.8 142.4 93.3 87.0 74.4 45.7 60.9 120.7 116.4 33.7 64.0 63.5 49.2 43.5 52.1 57.9 55.4 62.1 79.8 61.1 49.7 60.8 8.0 9.3 4.1 9.6 15.8 13.1 18.9 12.4 11.1 14.8 13.7 14.9 15.4 0.0 19.6 14.4 12.1 16.9 9.9 31.8 33.6 32.8 46.7 33.3 34.4 33.9 32.0 33.2 34.0 33.5 35.6 34.4 19.2 22.6 50.6 20.8 31.1 36.2 130.9 37.5 0.0 38.2 43.8 69.2 31.5 63.6 57.0 0.0 78.8 11.1 38.8 201.5 51.8 22.3 60.9 25.7 31.4 41.5 19.5 106.0 39.5 63.3 30.2 28.1 33.9 43.1 25.7 16.4 33.7 47.8 0.0 106.3 47.7 103.7 21.7 15.7 18.8 35.4 19.6 35.6 43.1 26.1 0.0 12.3 93.5 180.2 49.8 26.1 32.7 23.1 48.2 39.6 106.3 63.8 0.0 39.5 24.9 52.4 247.8 127.1 56.5 41.9 65.0 18.8 55.8 52.6 53.7 MUL1 "C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218" ENSG00000090432 "Mitochondrial E3 ubiquitin protein ligase 1" Q969V5 1 20499448-20508151 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026827 Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA026827: AB_10601137" "unprognostic (1.39e-1)" "unprognostic (2.73e-2)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (6.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (5.86e-3)" "unprognostic (4.05e-1)" "unprognostic (9.10e-2)" "prognostic favorable (6.15e-14)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (2.37e-1)" 16.7 18.1 18.1 12.0 18.7 28.8 16.2 19.9 19.4 15.9 23.3 21.2 14.2 20.4 11.1 21.2 19.6 14.9 33.7 17.8 19.4 19.5 24.6 15.8 13.6 20.3 19.1 19.1 19.8 36.3 14.6 16.3 20.1 16.0 15.7 7.4 19.3 20.0 35.5 21.8 15.8 20.0 18.7 15.2 18.7 12.2 19.5 12.0 16.2 50.4 15.0 19.2 15.5 19.9 34.1 32.1 18.1 37.9 38.5 21.6 19.6 32.9 39.1 40.1 38.2 19.9 54.8 25.4 35.9 46.8 30.4 50.3 32.9 47.5 28.9 25.4 26.1 19.4 20.4 29.2 45.2 27.0 32.0 35.3 61.6 41.1 42.3 23.4 26.5 22.5 25.8 30.1 44.1 17.3 16.4 18.1 18.7 28.1 30.3 15.8 22.8 32.9 47.1 18.7 18.4 27.3 29.6 31.2 40.5 14.6 22.0 25.6 30.2 38.8 22.3 34.1 29.9 34.9 32.9 27.3 30.4 36.1 36.7 36.2 30.0 38.2 33.1 34.7 34.4 25.3 24.8 33.8 29.6 22.8 28.1 27.6 26.7 32.3 30.7 22.8 37.9 34.0 18.1 18.7 19.9 19.4 17.8 19.4 20.3 19.1 20.1 18.7 19.5 19.9 14.5 22.4 10.3 10.4 9.8 5.2 9.2 13.9 5.2 13.5 12.3 11.9 16.6 10.0 9.5 18.4 6.2 37.1 13.2 21.6 11.7 26.3 2.2 7.7 9.5 13.1 8.5 8.6 4.9 23.4 22.5 13.9 7.7 9.4 3.8 14.7 13.6 17.6 23.0 13.5 6.8 12.9 16.2 10.0 6.5 4.0 13.1 9.3 19.6 2.8 15.5 16.0 16.5 5.5 6.0 25.6 14.6 15.4 13.1 9.2 13.2 10.6 9.6 11.9 19.7 11.9 14.7 14.6 15.4 7.4 7.1 37.6 9.2 18.0 12.2 10.7 NAA38 "LSMD1, MGC14151, PFAAP2" ENSG00000183011 "N-alpha-acetyltransferase 38, NatC auxiliary subunit" Q9BRA0 17 7856685-7885238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059189 Supported Nucleoplasm "Intracellular and membrane" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA059189: " "unprognostic (6.84e-2)" "unprognostic (1.65e-3)" "unprognostic (1.30e-2)" "unprognostic (1.85e-3)" "unprognostic (2.76e-2)" "unprognostic (3.35e-1)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (2.27e-1)" "unprognostic (7.28e-3)" "unprognostic (1.48e-3)" "unprognostic (3.31e-1)" "unprognostic (5.83e-3)" "unprognostic (1.58e-1)" "unprognostic (6.02e-2)" "unprognostic (2.66e-1)" "unprognostic (9.75e-2)" 72.1 102.2 137.4 33.3 142.4 76.0 67.3 143.6 188.0 58.3 135.3 77.4 30.8 54.9 30.9 65.8 57.4 29.1 99.7 139.4 139.3 87.6 67.8 50.7 45.7 137.7 137.3 45.3 60.1 76.6 73.0 22.6 137.9 71.5 27.0 29.4 56.2 31.8 130.4 59.5 49.2 24.5 138.1 72.6 65.9 97.8 142.5 45.2 60.1 93.4 31.4 60.0 55.5 142.0 131.4 234.9 129.4 132.9 70.8 78.3 44.8 59.7 68.4 108.3 89.9 89.0 54.6 89.6 98.5 63.6 69.2 105.4 69.8 110.3 26.8 134.1 318.2 137.3 279.7 131.0 68.4 38.6 101.9 114.3 60.4 71.0 46.3 74.5 105.9 201.9 29.1 95.3 63.6 157.3 140.0 91.6 29.2 98.9 271.5 142.0 59.6 59.4 101.0 72.6 57.6 110.5 46.6 111.1 87.3 18.7 68.8 100.0 57.6 72.2 52.0 59.0 170.8 39.1 43.8 34.8 121.5 159.1 72.2 313.1 275.2 196.9 176.1 244.0 163.4 273.8 186.3 181.9 332.4 234.2 167.1 173.6 201.1 152.9 239.8 304.0 215.3 299.0 137.4 142.4 143.6 188.0 139.4 139.3 137.7 137.3 137.9 138.1 142.5 142.0 263.1 76.9 140.5 16.3 117.8 94.1 85.8 171.8 144.5 98.5 218.1 305.4 344.3 128.7 107.7 253.8 50.1 160.2 107.4 227.2 518.5 100.6 646.3 189.4 104.9 183.6 226.6 201.2 18.3 158.4 128.0 102.6 80.5 133.1 100.1 131.1 213.5 381.3 210.5 40.4 21.7 211.2 146.5 222.8 96.8 1601.4 116.8 149.9 76.5 14.0 195.2 221.6 182.3 34.7 13.3 134.0 161.6 113.2 161.7 86.8 184.1 468.0 107.1 126.5 111.7 70.2 109.8 120.5 132.4 182.1 99.4 91.9 103.5 175.3 289.5 129.3 NAP1L4 NAP2 ENSG00000205531 "Nucleosome assembly protein 1 like 4" Q99733 11 2944431-2992377 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011567 Approved Supported Nucleoplasm NA NA 3100000 "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB011567: AB_776638" "unprognostic (1.61e-1)" "prognostic favorable (9.77e-4)" "unprognostic (8.99e-2)" "unprognostic (9.64e-3)" "unprognostic (2.96e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (1.80e-1)" "unprognostic (6.44e-2)" "unprognostic (1.77e-1)" "unprognostic (6.73e-2)" "unprognostic (2.31e-1)" "unprognostic (6.10e-3)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.55e-4)" "unprognostic (1.54e-1)" 39.6 43.5 44.3 36.1 59.2 50.3 41.3 53.0 178.1 46.7 70.3 60.3 20.1 45.4 17.3 79.6 41.2 32.5 111.4 41.3 52.1 63.7 56.2 40.5 65.7 57.2 53.8 42.9 38.0 63.5 61.4 36.8 60.2 51.9 34.2 38.6 66.4 32.1 146.1 49.0 53.8 39.1 52.2 59.0 56.6 87.4 56.4 78.8 44.6 110.7 75.8 61.9 52.1 72.2 82.8 59.9 81.7 65.7 83.9 92.4 37.7 159.8 104.1 145.4 132.5 129.7 208.4 149.5 95.3 98.0 15.1 140.0 21.9 136.3 166.8 159.2 57.5 106.7 151.4 168.2 57.7 93.0 110.5 77.8 65.1 78.6 59.1 12.0 88.9 77.6 139.3 150.7 128.0 74.5 206.4 4.2 199.8 98.9 75.2 101.4 98.1 117.0 12.2 131.7 121.4 104.3 80.5 118.1 78.3 82.5 7.3 7.4 67.8 112.5 104.4 152.4 13.8 79.3 136.5 201.5 8.4 66.0 75.3 67.5 22.9 32.6 42.3 24.0 39.9 24.7 51.9 53.0 27.2 28.4 45.7 52.1 14.5 57.6 30.4 25.0 70.5 48.0 44.3 59.2 53.0 178.1 41.3 52.1 57.2 53.8 60.2 52.2 56.4 72.2 53.6 44.8 49.8 56.2 64.3 70.1 67.4 76.9 83.1 80.4 54.6 48.3 200.4 42.9 69.0 75.4 45.9 103.8 99.4 37.2 97.8 78.7 97.0 107.7 65.9 55.4 45.4 168.7 36.9 50.4 109.2 56.6 54.0 91.1 74.6 100.6 43.5 50.0 47.3 65.6 56.6 41.4 67.1 30.8 44.7 142.6 48.1 49.7 35.6 38.4 65.3 67.5 95.8 60.8 125.3 74.1 26.8 50.0 100.7 76.1 39.8 76.9 92.6 68.1 46.0 58.8 64.7 166.1 129.0 102.3 66.9 91.3 123.8 79.7 55.1 83.7 NAPA ENSG00000105402 "NSF attachment protein alpha" P54920 19 47487637-47515091 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010100, HPA046149, HPA050196" Approved Uncertain Cytosol NA NA 2200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "CAB010100: AB_628263, HPA046149: AB_2679557, HPA050196: AB_2681048" "unprognostic (9.83e-2)" "unprognostic (9.43e-3)" "unprognostic (1.12e-2)" "unprognostic (1.76e-3)" "unprognostic (9.72e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (5.61e-2)" "unprognostic (2.42e-3)" "unprognostic (1.09e-3)" "prognostic favorable (4.26e-9)" "unprognostic (4.04e-2)" "unprognostic (4.17e-2)" "unprognostic (8.55e-2)" "unprognostic (2.90e-2)" 83.0 147.5 104.8 56.8 112.1 115.2 83.6 112.4 146.1 87.2 89.8 79.5 61.9 102.0 54.5 122.7 86.0 63.7 112.9 125.1 102.5 98.6 153.2 79.8 57.0 120.9 99.8 66.4 92.0 101.1 96.5 56.9 119.3 105.1 50.8 83.7 124.3 94.6 180.2 131.9 62.4 72.6 97.3 66.4 83.6 79.3 111.2 85.2 74.6 116.8 53.1 76.7 85.7 112.8 73.1 99.3 48.1 85.3 100.4 80.9 36.7 78.1 98.7 189.3 229.1 76.1 44.3 55.8 41.5 110.4 119.1 56.3 77.7 98.1 72.8 89.2 84.6 70.1 88.5 93.6 256.9 80.6 124.5 122.0 70.2 77.0 47.6 38.1 92.1 74.9 67.0 150.0 123.7 66.2 115.7 284.6 40.5 110.7 75.7 79.8 42.2 82.6 149.6 133.5 174.9 67.6 101.0 126.4 76.6 43.8 98.9 136.9 91.0 97.4 51.3 83.9 93.6 94.5 143.7 76.9 176.3 89.5 102.5 196.4 165.0 313.1 96.1 189.8 81.3 68.7 82.9 94.3 132.3 70.3 84.8 85.3 187.9 111.1 201.1 209.9 112.2 209.4 104.8 112.1 112.4 146.1 125.1 102.5 120.9 99.8 119.3 97.3 111.2 112.8 59.1 12.8 41.5 19.9 48.6 63.3 91.1 73.5 92.2 55.1 69.5 63.5 3.8 72.9 44.5 51.5 27.1 106.4 73.3 89.1 178.1 110.9 44.2 40.8 37.5 49.3 83.6 89.9 30.5 99.8 69.0 48.0 94.8 70.0 64.7 23.8 39.7 89.6 131.1 35.3 21.7 62.6 99.7 58.4 69.1 37.4 42.9 87.7 97.8 14.0 79.1 76.7 66.9 11.1 21.8 100.2 69.8 46.3 92.9 50.5 80.3 99.0 20.1 47.3 92.1 44.3 63.0 119.0 73.7 97.4 68.6 228.9 58.0 61.7 50.7 75.5 NARS2 "DFNB94, FLJ23441, SLM5" ENSG00000137513 "Asparaginyl-tRNA synthetase 2, mitochondrial" Q96I59 11 78435968-78574874 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Leigh syndrome, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026793 Supported Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Mitochondria" Cytosol "HPA026793: AB_1848833" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (5.73e-3)" "unprognostic (1.79e-3)" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (5.62e-2)" "unprognostic (4.62e-3)" "prognostic favorable (1.39e-5)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.22e-6)" "unprognostic (8.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" 7.3 11.9 10.7 6.8 12.3 6.2 11.1 12.4 13.3 9.6 19.8 11.3 10.3 9.1 11.2 8.1 9.9 7.0 11.7 10.4 11.7 19.0 23.5 7.6 9.6 11.7 13.9 11.4 10.6 11.4 7.6 8.0 13.1 10.8 10.9 13.4 10.7 7.3 23.5 7.2 9.7 7.4 11.3 7.4 9.9 7.5 11.4 11.7 11.5 19.6 9.7 8.7 8.1 12.3 16.7 22.8 23.5 15.4 16.1 13.5 19.5 13.5 13.1 20.6 16.9 39.4 17.4 40.9 34.1 8.7 19.8 21.5 39.9 26.3 28.3 27.0 21.3 28.9 17.3 33.7 13.3 31.3 10.1 9.4 16.8 18.1 32.0 18.3 17.9 33.7 44.5 11.0 23.1 19.4 32.7 50.3 25.6 67.3 27.3 33.6 38.2 55.5 27.2 23.0 27.8 17.5 20.1 25.4 35.5 25.1 24.1 12.3 10.9 27.7 32.8 32.0 23.1 18.1 33.1 91.1 5.4 27.7 19.2 9.5 9.3 4.4 11.1 10.4 13.8 17.6 12.8 12.5 16.6 15.0 18.5 16.7 2.0 20.3 12.8 12.7 10.5 10.3 10.7 12.3 12.4 13.3 10.4 11.7 11.7 13.9 13.1 11.3 11.4 12.3 5.8 19.2 26.4 27.7 14.5 13.5 14.2 12.0 12.5 5.2 9.4 6.5 8.8 5.7 10.3 5.5 2.1 20.0 4.4 4.0 29.4 9.5 13.1 10.1 7.4 6.6 12.0 9.2 34.7 7.3 23.6 9.0 10.2 9.0 8.2 14.0 2.5 19.8 12.4 0.0 45.1 8.3 22.4 6.3 11.6 5.4 7.8 6.3 17.8 45.0 2.9 6.3 4.1 42.7 47.7 7.5 9.9 4.9 14.6 17.5 7.0 28.9 10.2 9.0 6.6 7.5 8.8 8.6 19.5 12.0 13.8 15.3 7.8 9.0 14.6 10.7 NDUFA1 "CI-MWFE, MWFE" ENSG00000125356 "NADH:ubiquinone oxidoreductase subunit A1" O15239 X 119871832-119876662 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3202.9;Distal tubular cells: 2191.3;Proximal tubular cells: 1764.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029768, HPA054359" Enhanced Approved Mitochondria,Cytosol No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Mitochondria "HPA029768: AB_2673192, HPA054359: AB_2682461" "unprognostic (1.72e-1)" "unprognostic (3.00e-3)" "unprognostic (3.12e-2)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (7.34e-3)" "unprognostic (1.56e-1)" "unprognostic (8.20e-3)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (8.11e-3)" "unprognostic (4.77e-2)" "prognostic favorable (3.48e-4)" "unprognostic (1.16e-1)" "unprognostic (3.62e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-3)" 260.4 276.7 541.8 179.3 547.2 316.3 275.0 560.4 746.6 226.5 637.9 467.4 387.4 132.4 323.9 145.0 193.2 133.0 983.7 539.2 555.3 495.1 449.6 153.8 186.7 549.0 541.6 149.3 228.5 773.9 121.4 171.4 551.2 185.8 371.3 398.6 280.0 240.2 1381.0 90.8 334.6 180.7 545.6 169.4 297.4 65.8 551.2 273.2 173.3 1367.9 219.4 228.5 90.5 549.6 436.8 561.9 342.0 365.6 466.3 317.8 423.6 346.6 395.9 297.8 368.1 326.5 377.8 385.1 509.4 431.0 514.7 416.5 555.7 392.8 354.6 492.2 751.7 380.6 1110.1 750.5 357.0 575.9 387.2 485.4 577.0 296.5 232.5 413.2 389.1 372.4 230.9 553.4 435.6 965.3 412.5 563.2 489.1 1214.3 988.4 405.3 315.2 1169.8 887.0 765.2 255.9 319.8 714.9 871.1 479.6 476.5 224.2 653.8 395.1 209.4 198.2 422.7 672.5 469.4 798.3 524.9 377.5 719.5 262.1 1064.7 680.6 822.0 486.1 726.1 468.4 560.6 540.8 516.7 745.6 447.7 435.9 523.1 851.5 468.5 815.5 809.1 675.4 780.5 541.8 547.2 560.4 746.6 539.2 555.3 549.0 541.6 551.2 545.6 551.2 549.6 251.9 160.3 188.6 10.7 261.6 213.7 251.4 991.0 194.1 156.2 268.0 322.7 3202.9 511.9 445.8 562.8 79.2 396.5 273.9 1264.2 2191.3 503.6 34.2 332.0 237.9 228.9 459.0 272.3 12.3 512.5 416.1 266.9 322.1 348.9 210.3 177.5 260.3 1022.5 661.7 82.4 14.8 907.2 581.8 413.5 350.6 43.8 294.5 329.3 570.9 14.0 492.3 364.2 277.1 8.0 16.5 506.4 1024.5 285.1 389.2 228.8 1546.3 1764.0 443.2 231.2 216.9 208.4 289.9 50.8 105.2 394.3 249.3 380.6 255.7 126.7 887.7 339.3 NDUFA11 B14.7 ENSG00000174886 "NADH:ubiquinone oxidoreductase subunit A11" Q86Y39 19 5891276-5904006 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA072209 Uncertain Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA072209: AB_2686495" "unprognostic (2.24e-1)" "prognostic favorable (4.54e-5)" "unprognostic (8.20e-3)" "prognostic favorable (3.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.73e-2)" "unprognostic (6.30e-2)" "unprognostic (7.26e-3)" "unprognostic (3.95e-1)" "unprognostic (4.20e-2)" "unprognostic (1.67e-3)" "unprognostic (9.02e-2)" "unprognostic (1.12e-2)" "unprognostic (2.91e-1)" "unprognostic (1.16e-1)" "unprognostic (3.40e-2)" "unprognostic (6.16e-3)" 199.0 429.8 203.3 93.4 207.7 158.1 188.9 226.1 305.6 202.1 205.3 312.2 124.9 219.6 53.1 283.4 201.5 106.6 687.5 206.8 223.5 290.2 380.5 155.1 145.3 212.7 213.8 200.7 205.7 138.7 205.9 96.9 215.7 228.3 56.1 31.7 231.2 105.4 425.5 187.6 185.6 89.4 218.3 196.4 250.4 96.3 218.8 120.7 188.9 330.6 62.7 209.4 215.5 225.2 315.2 227.6 168.7 273.1 138.9 231.5 191.2 209.8 243.9 369.4 341.5 271.9 155.5 300.4 320.0 209.6 163.9 195.4 118.6 250.8 85.7 271.2 466.9 124.4 194.5 434.4 374.3 188.8 174.4 317.3 221.9 219.9 106.6 147.6 250.7 284.5 257.3 316.4 192.4 228.2 484.1 325.0 249.9 249.1 609.2 325.0 214.2 427.9 238.3 194.9 236.2 254.3 163.5 254.3 381.5 72.9 196.1 395.0 224.9 202.8 194.7 410.1 340.1 493.5 460.1 400.6 341.0 443.1 263.7 421.2 526.8 313.4 313.2 440.5 323.9 394.4 341.2 314.6 461.1 343.7 321.0 281.1 239.0 303.9 387.8 550.1 474.0 870.2 203.3 207.7 226.1 305.6 206.8 223.5 212.7 213.8 215.7 218.3 218.8 225.2 189.9 144.2 198.0 22.5 179.2 205.6 236.8 306.8 99.6 60.1 279.3 430.3 436.9 267.4 202.9 292.4 25.0 585.4 164.2 429.9 841.2 286.0 157.4 199.8 146.9 175.6 351.5 208.9 12.9 301.6 595.6 224.3 114.7 137.6 213.0 135.5 272.7 735.4 423.7 50.5 16.6 477.0 207.5 347.7 234.1 452.4 194.8 197.7 286.4 14.0 403.3 198.0 220.4 5.5 31.2 287.1 446.6 167.3 208.5 283.5 606.9 1107.9 176.7 89.6 118.3 174.3 210.0 97.2 91.8 162.5 243.5 593.4 156.9 159.0 451.1 241.3 NDUFA12 "B17.2, DAP13" ENSG00000184752 "NADH:ubiquinone oxidoreductase subunit A12" Q9UI09 12 94897055-95003748 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 558.6;tongue: 563.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039903 Supported Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "HPA039903: AB_10795516" "unprognostic (2.76e-1)" "unprognostic (5.32e-3)" "unprognostic (1.17e-1)" "unprognostic (2.56e-2)" "unprognostic (2.85e-1)" "unprognostic (4.03e-2)" "unprognostic (3.05e-2)" "unprognostic (6.68e-2)" "unprognostic (1.67e-1)" "unprognostic (2.47e-2)" "unprognostic (1.89e-1)" "unprognostic (1.64e-1)" "unprognostic (3.13e-3)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (6.13e-2)" "unprognostic (3.27e-2)" 100.2 94.1 158.6 73.9 162.8 93.2 77.1 168.9 228.1 67.8 159.8 148.6 109.3 66.8 87.1 89.8 77.8 52.9 361.8 161.3 172.6 133.8 143.7 70.3 92.5 166.4 162.1 64.7 59.6 159.5 73.5 79.5 164.1 74.7 143.9 106.8 75.3 77.8 558.6 74.2 101.5 98.4 162.6 97.6 87.7 58.9 165.1 108.9 89.6 563.1 122.0 81.0 73.0 161.1 255.3 281.1 223.6 160.8 183.3 171.8 165.8 118.8 178.5 258.5 234.6 347.6 125.8 293.7 68.8 187.6 141.1 188.2 236.1 278.4 296.7 254.8 282.9 241.2 218.6 358.8 186.3 344.0 285.3 183.0 352.4 215.7 266.9 270.4 222.2 246.0 235.2 130.4 260.8 381.1 238.6 533.6 167.0 313.7 484.0 179.9 189.4 335.2 262.5 393.9 213.2 128.5 201.3 287.3 164.6 193.9 287.2 226.9 243.5 134.1 134.0 195.0 204.2 207.5 349.9 443.7 80.6 293.6 211.2 643.9 420.5 228.2 354.8 512.5 336.4 482.8 479.5 429.9 576.2 415.5 631.9 455.9 62.0 464.6 506.6 355.5 570.8 814.8 158.6 162.8 168.9 228.1 161.3 172.6 166.4 162.1 164.1 162.6 165.1 161.1 213.5 73.7 68.4 26.8 81.3 108.6 163.9 364.5 71.2 67.4 87.9 171.7 2159.0 135.8 168.3 108.5 64.6 254.0 127.9 172.0 620.3 162.0 240.0 110.3 98.9 206.0 85.3 86.5 19.6 163.9 254.5 172.6 67.2 100.7 58.3 103.5 109.2 149.1 192.3 37.0 29.0 171.8 244.1 103.6 161.9 122.1 97.6 111.1 160.1 13.1 203.5 141.6 199.8 20.6 22.3 234.6 228.8 133.5 98.8 123.8 229.9 338.3 134.7 130.5 105.2 120.8 291.2 156.3 109.8 127.9 127.7 209.6 120.2 181.9 219.2 182.0 NDUFA13 "B16.6, CDA016, CGI-39, GRIM-19, GRIM19" ENSG00000186010 "NADH:ubiquinone oxidoreductase subunit A13" Q9P0J0 19 19515736-19529054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Electron transport, Host-virus interaction, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2947.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041213 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA041213: AB_10794988" "unprognostic (2.87e-1)" "unprognostic (2.88e-3)" "unprognostic (9.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "unprognostic (5.78e-2)" "unprognostic (6.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.81e-1)" "unprognostic (1.83e-3)" "unprognostic (1.26e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (1.33e-1)" "unprognostic (2.37e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-2)" 268.1 248.1 586.0 184.1 601.2 318.9 226.6 612.2 726.3 188.2 632.2 324.0 268.5 129.8 414.0 288.3 253.0 165.0 987.1 577.4 609.2 274.5 301.3 154.8 234.9 600.9 585.1 168.3 274.3 541.3 154.7 186.6 588.3 216.1 212.4 100.7 272.8 220.4 1093.2 183.1 245.1 193.5 593.6 160.6 251.2 208.5 624.2 254.5 221.2 1102.9 178.5 250.9 103.5 607.7 371.4 405.5 443.7 531.6 460.2 416.2 606.4 345.8 488.3 500.0 492.2 639.4 584.9 442.6 952.2 495.2 261.4 307.2 313.0 477.6 177.3 276.5 1052.6 308.9 590.9 834.1 448.0 601.1 517.0 546.5 483.7 322.7 335.5 296.3 382.8 533.1 428.6 728.2 400.3 1115.4 811.2 880.9 528.4 846.6 1004.4 536.0 263.0 830.2 711.1 782.6 508.9 633.2 350.0 551.7 481.1 225.2 367.7 1035.9 307.3 538.4 177.5 583.8 541.0 543.6 430.6 510.3 428.4 624.2 390.8 1210.3 1162.6 963.4 758.6 1263.4 678.0 1284.6 874.1 838.9 1165.9 1097.3 831.6 775.7 411.9 779.9 1054.3 979.4 1246.2 2090.8 586.0 601.2 612.2 726.3 577.4 609.2 600.9 585.1 588.3 593.6 624.2 607.7 155.1 131.4 184.8 33.0 194.5 129.0 75.9 346.9 117.8 64.8 211.3 181.2 514.5 224.4 251.2 250.1 25.0 426.6 136.6 951.6 610.5 566.0 411.8 154.5 111.5 131.4 556.3 185.3 22.7 578.5 357.2 173.1 225.3 130.5 259.3 51.3 182.4 422.6 333.6 42.1 27.2 719.7 268.5 307.4 197.9 2947.1 153.4 198.3 263.3 19.7 456.7 186.3 183.4 17.6 41.2 490.5 931.9 129.1 272.0 75.0 1114.7 772.0 236.5 84.2 92.1 91.6 196.2 80.6 111.5 210.0 127.0 498.4 177.5 48.0 683.0 87.4 NDUFA2 B8 ENSG00000131495 "NADH:ubiquinone oxidoreductase subunit A2" O43678 5 140638740-140647771 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1052.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035933 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA035933: AB_10669661" "unprognostic (4.48e-1)" "prognostic favorable (6.53e-4)" "unprognostic (3.61e-2)" "unprognostic (1.96e-2)" "unprognostic (6.15e-2)" "unprognostic (5.39e-3)" "unprognostic (4.01e-1)" "unprognostic (2.75e-2)" "unprognostic (1.60e-1)" "unprognostic (4.39e-3)" "unprognostic (1.84e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.78e-2)" "unprognostic (9.96e-2)" "unprognostic (4.22e-1)" "unprognostic (1.30e-3)" 76.1 127.9 131.0 52.3 131.3 96.0 67.3 139.0 156.1 49.2 139.8 81.0 90.2 43.8 79.0 73.5 50.3 45.8 197.3 129.8 137.1 144.9 145.1 53.3 66.1 133.3 131.0 54.9 81.5 99.8 79.1 47.3 133.3 68.7 60.9 51.8 102.2 46.8 283.8 52.4 86.1 31.6 135.8 72.6 90.8 79.7 134.9 78.1 64.2 233.0 48.2 55.5 51.3 142.3 131.1 202.5 91.3 195.9 113.6 84.5 117.8 76.6 69.0 99.4 120.4 328.1 149.5 125.4 191.2 65.9 122.9 103.7 88.4 153.9 57.1 120.6 226.6 80.1 170.6 248.3 67.7 138.7 102.6 100.6 116.6 65.4 47.5 84.3 101.2 111.8 86.9 194.4 93.1 204.9 168.4 285.9 97.5 152.8 203.6 144.7 110.4 212.7 167.5 146.4 119.6 99.4 104.7 292.2 221.8 81.9 269.7 216.3 70.1 113.9 84.8 96.3 125.9 214.2 339.4 190.1 132.3 152.8 65.0 195.0 304.6 311.5 133.1 270.1 137.4 222.0 141.1 143.0 258.1 178.0 127.0 135.6 255.8 156.8 219.9 273.3 205.6 322.8 131.0 131.3 139.0 156.1 129.8 137.1 133.3 131.0 133.3 135.8 134.9 142.3 138.4 109.0 125.4 10.4 127.5 97.8 116.4 311.1 105.3 87.4 182.2 203.5 314.4 200.1 199.7 244.6 37.5 294.1 168.0 499.6 815.9 187.8 526.6 194.5 114.1 115.8 193.2 222.2 6.5 220.4 231.0 115.9 122.9 171.9 92.5 121.2 169.6 516.1 291.9 53.8 7.7 337.9 258.4 251.3 144.6 435.1 165.0 168.0 190.3 5.6 265.1 227.3 211.2 5.5 12.9 194.7 474.4 153.4 151.8 153.8 682.9 1052.3 207.9 113.0 118.3 104.8 139.0 182.7 237.0 165.8 117.1 222.5 124.3 196.1 367.5 164.4 NDUFA4 "CI-9k, COXFA4, MLRQ" ENSG00000189043 "NDUFA4 mitochondrial complex associated" O00483 7 10931943-10940153 "Disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 513.5;skeletal muscle: 525.0;tongue: 652.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4615.5;Distal tubular cells: 3960.0;Proximal tubular cells: 3331.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Approved Supported Mitochondria NA NA 50000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.83e-1)" "unprognostic (6.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.51e-1)" "unprognostic (2.16e-1)" "unprognostic (4.97e-3)" "unprognostic (3.85e-1)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (3.90e-2)" "unprognostic (8.65e-3)" "unprognostic (1.74e-1)" "prognostic favorable (4.61e-8)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-3)" "unprognostic (2.08e-1)" 78.6 90.1 188.7 40.8 196.2 67.5 76.0 192.9 263.4 54.7 192.8 84.1 74.2 74.2 81.1 66.9 69.5 36.2 513.5 201.9 205.0 156.6 140.3 62.8 42.5 194.4 189.6 60.1 61.3 251.9 23.3 31.6 197.6 66.0 56.6 128.4 108.6 84.4 525.0 58.3 58.8 60.9 194.1 59.6 107.0 24.3 194.3 64.0 66.3 652.5 46.1 73.7 54.1 200.1 55.3 90.9 155.0 176.8 84.0 78.4 70.3 68.2 63.2 61.3 53.6 115.2 144.7 104.6 63.0 96.7 168.0 94.1 102.1 79.4 66.5 52.2 74.0 88.2 93.4 108.6 73.2 123.3 84.3 84.8 78.4 75.4 66.0 116.7 86.6 92.7 133.2 139.0 129.8 103.8 56.2 109.3 169.2 364.2 181.6 74.7 108.6 118.6 158.0 115.4 95.2 99.7 106.9 303.7 64.7 210.3 191.6 149.6 76.8 73.3 102.0 107.0 115.0 84.6 115.8 120.5 101.3 130.8 232.5 236.7 110.2 160.6 74.3 135.8 88.3 95.7 103.3 93.9 138.9 74.6 106.1 93.3 25.3 79.4 146.4 131.2 131.6 192.8 188.7 196.2 192.9 263.4 201.9 205.0 194.4 189.6 197.6 194.1 194.3 200.1 422.2 490.4 470.7 52.9 366.9 407.1 605.8 1642.7 307.9 521.0 742.3 936.0 4615.5 843.6 879.3 952.7 266.9 875.9 357.5 543.8 3960.0 865.1 160.6 626.2 471.6 447.0 209.7 358.3 54.1 955.5 763.9 557.9 404.7 477.7 576.4 507.5 656.1 1887.5 964.5 158.2 72.7 780.8 1373.2 589.0 589.8 106.8 493.6 517.6 916.0 49.6 596.6 721.5 374.9 36.7 57.9 776.6 626.7 784.3 467.9 696.6 596.2 3331.1 803.0 666.0 335.2 546.5 846.5 172.7 295.5 581.7 482.9 658.8 389.1 443.5 712.4 803.2 NDUFA5 "B13, CI-13kB, CI-13KD-B, NUFM, UQOR13" ENSG00000128609 "NADH:ubiquinone oxidoreductase subunit A5" Q16718 7 123536997-123557904 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 403.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 717.3;Distal tubular cells: 1070.2;Proximal tubular cells: 667.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043175 Supported NA NA 81000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043175: AB_10793992" "prognostic favorable (8.47e-5)" "unprognostic (4.00e-2)" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "unprognostic (4.90e-2)" "unprognostic (3.26e-1)" "unprognostic (2.23e-1)" "unprognostic (3.46e-2)" "unprognostic (1.81e-1)" "unprognostic (2.14e-2)" "unprognostic (1.37e-1)" "unprognostic (9.20e-2)" "prognostic favorable (3.99e-9)" "unprognostic (3.39e-1)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (2.73e-3)" 55.2 129.2 94.7 34.1 99.9 34.8 68.8 94.2 130.1 51.3 93.4 78.5 77.6 47.5 71.5 51.0 51.8 47.0 215.7 100.5 108.4 175.3 114.9 44.4 40.0 92.4 97.6 42.2 41.2 170.1 58.3 39.7 98.5 72.8 73.3 127.1 75.6 63.1 285.1 27.2 72.7 46.9 92.6 35.4 77.4 38.3 94.4 52.8 136.6 403.3 42.5 57.8 33.5 91.6 65.9 41.8 76.3 76.6 64.5 58.6 39.5 57.4 63.1 46.8 61.1 47.1 58.2 108.6 54.8 58.8 91.0 60.7 83.9 75.2 74.3 89.6 71.7 68.8 85.9 78.1 62.7 140.5 56.4 58.6 65.9 45.3 47.3 84.1 68.4 75.4 213.9 104.9 84.4 45.5 127.3 162.1 100.3 154.3 107.0 69.2 75.0 146.6 129.5 63.7 144.9 86.3 76.1 286.2 90.3 102.5 65.6 104.7 53.1 58.9 31.7 262.0 88.5 111.2 109.4 116.4 112.7 106.2 75.7 57.8 26.2 31.5 38.2 48.7 55.4 53.6 48.6 44.9 37.1 41.6 52.5 54.0 9.2 52.7 54.8 40.0 55.8 60.4 94.7 99.9 94.2 130.1 100.5 108.4 92.4 97.6 98.5 92.6 94.4 91.6 99.2 102.5 100.4 38.2 108.7 112.5 146.2 280.3 74.6 183.6 113.0 100.8 717.3 102.9 160.6 165.5 83.4 160.6 105.6 119.0 1070.2 132.2 359.6 123.4 91.1 91.8 138.0 91.1 65.2 89.6 156.8 110.5 108.6 128.6 88.7 59.2 66.0 170.6 109.6 127.9 48.5 168.6 295.0 67.2 92.5 77.5 90.1 94.9 202.7 19.7 65.7 264.6 77.2 32.2 29.2 86.2 130.9 112.1 82.0 107.1 210.2 667.6 158.6 214.7 118.3 97.4 133.7 179.0 99.0 94.7 110.2 158.4 102.3 116.9 172.2 147.0 NDUFA7 B14.5a ENSG00000267855 "NADH:ubiquinone oxidoreductase subunit A7" O95182 19 8308768-8321375 "Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 245.6" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 167.5;Proximal enterocytes: 183.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA059251, HPA071866" Enhanced Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA059251: AB_2683960, HPA071866: AB_2686465" "unprognostic (6.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (3.85e-1)" "unprognostic (2.18e-1)" "unprognostic (5.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.43e-2)" "unprognostic (3.40e-1)" "unprognostic (1.13e-3)" "unprognostic (1.81e-2)" "unprognostic (1.43e-1)" "unprognostic (1.09e-2)" "unprognostic (5.53e-2)" "unprognostic (1.29e-2)" "unprognostic (2.59e-2)" "unprognostic (9.35e-3)" 39.4 87.5 86.2 19.8 90.0 34.2 33.1 89.8 96.1 21.3 95.9 46.6 24.2 27.7 53.5 57.6 42.3 25.1 168.1 87.6 90.0 88.3 83.4 31.0 29.6 87.1 88.1 25.1 37.1 103.7 86.4 23.4 87.3 41.2 33.5 32.3 43.5 20.7 245.6 30.7 34.0 22.8 87.3 42.0 54.7 18.7 89.1 40.8 41.3 244.7 32.2 35.5 28.2 87.7 78.9 62.8 64.7 43.3 42.6 32.3 44.2 16.5 18.0 56.0 44.1 57.7 59.7 36.1 25.1 42.6 35.0 65.1 29.0 97.4 33.8 88.3 173.6 26.6 90.1 157.7 63.9 45.8 45.1 43.3 61.7 25.2 39.1 57.1 72.3 141.2 57.0 217.7 80.6 89.4 93.5 236.1 65.1 119.9 187.7 52.2 13.7 99.0 117.6 40.8 65.9 50.5 19.0 90.6 58.5 40.1 33.0 74.8 26.4 42.5 34.0 61.6 60.1 79.2 58.0 49.9 67.8 80.2 77.3 61.9 104.5 80.2 62.1 124.6 65.4 83.3 66.7 58.2 130.5 81.6 66.0 61.6 30.5 81.8 117.6 186.1 95.3 82.6 86.2 90.0 89.8 96.1 87.6 90.0 87.1 88.1 87.3 87.3 89.1 87.7 19.5 44.8 68.4 10.1 28.4 0.0 10.3 0.0 21.1 14.9 51.6 38.1 0.0 44.3 20.4 53.3 6.2 62.0 32.6 57.6 99.7 147.3 38.9 36.1 10.5 19.8 87.4 44.2 9.5 157.2 45.4 15.0 28.1 19.4 21.5 8.4 27.5 64.0 52.8 8.4 13.3 101.6 0.0 42.7 0.0 17.7 13.4 30.4 0.0 10.3 122.5 27.9 45.3 9.5 13.2 167.5 110.2 13.2 61.6 14.7 183.8 97.6 70.7 17.1 6.6 7.3 19.6 24.8 27.5 53.3 0.0 46.9 20.9 11.7 107.6 12.1 NDUFA8 "MGC793, PGIV" ENSG00000119421 "NADH:ubiquinone oxidoreductase subunit A8" P51970 9 122144058-122159779 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 380.1;tongue: 363.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 579.5;Distal tubular cells: 614.3;Early spermatids: 499.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041510, HPA041600" Enhanced Supported Mitochondria NA NA 25000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041510: AB_10794379, HPA041600: AB_10796778" "unprognostic (2.90e-1)" "unprognostic (2.27e-3)" "unprognostic (3.58e-1)" "unprognostic (3.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.98e-2)" "unprognostic (2.33e-2)" "unprognostic (6.98e-2)" "unprognostic (1.46e-2)" "unprognostic (4.12e-2)" "prognostic favorable (4.17e-6)" "unprognostic (1.80e-1)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (4.62e-2)" 54.2 74.2 139.4 33.9 146.0 28.6 53.9 146.0 159.3 44.8 142.6 101.4 65.8 46.6 86.8 57.1 62.3 39.3 380.1 144.7 148.4 97.9 81.5 37.0 43.0 141.4 139.7 35.7 46.1 137.4 56.9 48.2 141.6 57.9 88.2 72.0 72.3 61.9 259.1 44.2 53.6 73.9 138.7 41.4 75.3 95.5 145.8 48.6 53.3 363.3 56.2 57.8 40.9 141.7 84.8 154.1 99.5 132.0 105.7 96.4 123.3 96.0 114.1 130.0 108.5 197.0 81.9 123.1 92.6 113.6 234.6 206.8 191.3 208.7 127.0 121.5 132.6 96.9 254.2 172.6 113.3 172.7 95.5 106.1 200.3 130.0 82.9 118.1 189.1 134.8 151.0 89.6 150.3 215.6 108.1 112.1 91.2 377.1 293.1 85.0 156.7 179.4 189.4 116.0 172.1 67.6 151.0 176.7 122.6 100.9 187.6 82.1 123.2 71.2 70.9 135.2 109.3 100.1 176.1 123.8 148.0 110.7 120.2 17.4 82.1 66.8 78.3 100.9 76.2 88.0 71.3 77.3 109.2 92.8 76.0 80.3 13.7 79.0 88.7 114.2 91.9 74.7 139.4 146.0 146.0 159.3 144.7 148.4 141.4 139.7 141.6 138.7 145.8 141.7 70.6 28.9 40.4 16.3 38.6 48.3 73.8 298.1 43.9 47.2 61.0 73.5 579.5 48.6 128.0 82.8 29.2 130.5 34.1 87.3 614.3 103.8 499.0 80.1 52.4 98.5 77.4 100.6 19.4 101.6 113.1 70.3 47.9 52.9 20.3 68.5 60.7 110.9 124.4 45.4 26.0 105.7 185.1 40.5 42.0 121.1 56.5 48.8 94.3 18.7 72.9 91.3 65.9 14.1 17.9 100.8 80.3 75.2 56.9 91.1 163.4 249.8 113.0 59.0 26.3 52.5 114.8 294.9 116.2 67.0 56.8 126.6 36.6 104.4 136.3 86.4 NDUFA9 "CI-39k, COQ11, NDUFS2L, SDR22E1" ENSG00000139180 "NADH:ubiquinone oxidoreductase subunit A9" Q16795 12 4649095-4694317 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 617.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA042268: AB_2677922, HPA073212: AB_2686581" "unprognostic (2.26e-1)" "unprognostic (7.85e-3)" "unprognostic (3.67e-2)" "unprognostic (1.84e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (9.64e-3)" "unprognostic (3.02e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (3.45e-2)" "unprognostic (1.16e-1)" "prognostic favorable (2.57e-7)" "unprognostic (7.80e-2)" "unprognostic (1.71e-1)" "unprognostic (1.93e-2)" "prognostic favorable (5.75e-4)" 19.6 29.2 25.6 14.8 26.5 35.3 19.1 29.1 38.5 18.4 29.5 41.1 30.6 20.4 14.7 30.9 17.5 6.1 116.7 26.1 25.7 43.4 49.4 18.0 11.8 26.0 25.5 14.7 24.2 34.2 21.9 10.2 26.7 21.4 31.2 20.1 24.3 11.1 110.3 24.1 31.0 12.7 25.7 23.7 31.6 14.3 26.4 18.1 19.3 110.6 14.5 21.2 19.8 27.0 29.8 52.5 25.3 33.9 18.3 18.1 73.1 22.1 22.4 41.9 31.6 114.4 58.0 33.2 11.6 24.2 47.5 48.9 37.1 32.9 27.0 64.8 65.3 32.5 51.0 88.1 40.0 48.0 33.8 23.3 31.2 28.7 38.6 26.0 32.0 46.8 23.1 60.8 31.5 57.6 48.5 55.1 65.5 55.6 43.2 67.4 37.5 34.5 59.2 66.6 18.2 20.6 27.9 74.4 41.9 54.4 15.4 45.4 22.2 31.8 64.7 29.3 52.3 11.9 15.1 57.1 33.2 29.4 35.7 75.9 134.3 53.3 99.2 165.1 102.1 148.3 102.4 109.3 161.9 110.0 88.9 91.1 11.8 107.5 133.5 168.0 143.6 265.0 25.6 26.5 29.1 38.5 26.1 25.7 26.0 25.5 26.7 25.7 26.4 27.0 37.5 28.9 32.1 26.1 45.2 48.6 63.7 199.3 21.6 48.6 40.1 37.0 185.1 45.8 99.4 64.4 58.4 111.1 45.7 89.4 166.3 130.0 112.2 29.3 29.6 46.4 47.4 36.0 21.0 131.3 118.7 38.5 35.2 26.0 57.7 36.6 34.6 78.5 114.7 33.7 26.3 125.4 140.4 35.6 31.8 617.2 28.3 41.8 55.2 15.9 60.0 48.2 49.4 27.2 20.1 108.0 83.5 36.9 50.8 40.5 108.5 163.2 74.9 67.8 19.7 32.0 54.8 30.6 31.3 38.5 47.2 99.9 43.4 66.3 147.7 69.4 NDUFAF1 "CGI-65, CIA30" ENSG00000137806 "NADH:ubiquinone oxidoreductase complex assembly factor 1" Q9Y375 15 41387218-41409403 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 85.3;Spermatocytes: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039933, HPA040064" Supported Approved Mitochondria,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Mitochondria, Cytosol" "HPA039933: AB_10795265, HPA040064: AB_10795687" "unprognostic (2.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.72e-1)" "unprognostic (2.10e-3)" "unprognostic (2.38e-1)" "unprognostic (1.20e-1)" "prognostic favorable (2.88e-5)" "unprognostic (3.01e-1)" "unprognostic (2.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "prognostic favorable (3.34e-6)" "unprognostic (1.68e-1)" "unprognostic (3.23e-1)" "unprognostic (3.17e-2)" "unprognostic (2.05e-1)" 16.0 33.4 20.0 9.5 20.7 4.2 12.4 21.6 29.6 9.7 22.8 12.7 12.6 10.5 15.5 13.8 9.8 7.7 42.7 20.7 21.4 29.0 38.7 9.3 11.5 21.1 21.0 9.7 11.8 18.3 11.5 8.0 21.3 10.1 10.4 12.4 12.2 13.2 63.5 9.7 10.9 10.8 21.5 11.9 14.1 21.1 20.8 10.9 10.5 60.9 13.1 12.8 9.9 22.9 15.9 13.3 16.4 13.3 30.0 28.3 14.9 26.1 25.1 23.6 21.3 22.5 8.1 16.7 38.2 24.9 17.5 25.0 20.1 15.9 19.3 32.9 23.9 22.4 25.0 13.8 27.1 24.7 17.0 30.0 18.5 20.8 18.0 19.9 19.0 31.9 38.2 17.2 30.6 17.5 19.9 28.6 12.6 27.5 17.9 15.0 17.4 40.6 41.9 27.8 17.5 13.8 13.2 31.8 12.6 16.9 25.1 50.2 15.4 18.0 10.1 30.5 24.2 15.8 34.7 28.0 24.0 43.5 19.3 35.0 12.8 16.2 7.8 15.0 9.1 13.8 9.6 9.5 11.8 11.8 10.6 8.6 9.4 13.4 13.3 18.2 16.8 8.5 20.0 20.7 21.6 29.6 20.7 21.4 21.1 21.0 21.3 21.5 20.8 22.9 7.7 12.8 10.1 6.5 14.6 4.7 15.8 43.8 9.6 15.7 12.3 11.9 58.7 15.7 27.3 22.0 12.5 36.3 19.8 8.5 64.6 30.5 59.5 14.2 14.2 11.1 6.7 13.5 8.8 31.3 34.6 12.5 12.2 13.1 7.0 16.3 8.6 28.2 28.8 6.7 9.1 8.5 30.5 12.8 7.0 15.0 16.4 16.2 10.6 3.7 23.4 20.7 16.5 4.0 10.3 20.9 3.7 16.1 15.0 11.8 23.3 85.3 30.6 19.2 26.3 15.3 17.3 84.7 21.6 11.3 7.7 50.3 12.3 32.6 11.9 16.3 NDUFAF4 "bA22L21.1, C6orf66, HRPAP20, HSPC125, My013" ENSG00000123545 "NADH:ubiquinone oxidoreductase complex assembly factor 4" Q9P032 6 96889315-96897891 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 168.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046560 Uncertain Supported Mitochondria NA Yes "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046560: AB_10966700" "prognostic unfavorable (1.31e-4)" "unprognostic (1.32e-1)" "unprognostic (1.09e-2)" "unprognostic (1.14e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (6.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (2.78e-2)" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" 5.7 7.9 13.3 3.4 14.7 2.2 7.0 16.8 21.4 6.4 10.4 7.4 4.9 5.5 4.7 5.4 4.4 4.5 25.6 14.7 15.6 12.6 9.3 3.2 4.7 14.9 14.5 7.8 5.5 10.1 2.5 4.8 15.6 7.2 7.5 9.8 6.2 9.6 23.2 4.8 4.4 5.6 12.3 4.9 4.7 4.6 16.6 5.3 7.4 31.1 4.7 7.8 3.7 13.7 2.2 6.1 10.5 14.3 10.3 5.9 5.6 6.0 5.6 8.8 6.6 8.4 3.7 20.6 10.7 5.6 8.4 4.4 24.7 9.3 8.5 14.5 19.5 23.0 3.2 7.4 11.2 24.4 9.2 5.7 14.2 7.6 7.7 4.4 6.9 14.3 21.0 13.6 13.9 7.0 15.7 13.1 20.1 11.3 10.0 7.4 5.9 10.7 14.6 6.0 17.9 8.4 3.1 10.7 17.5 10.2 3.3 16.1 5.8 4.6 3.5 16.2 9.9 3.1 5.4 20.0 6.2 18.1 6.9 0.2 1.8 0.5 4.0 3.6 5.3 5.1 5.2 5.4 3.3 5.4 7.6 6.9 0.3 3.0 2.3 3.8 5.9 3.2 13.3 14.7 16.8 21.4 14.7 15.6 14.9 14.5 15.6 12.3 16.6 13.7 31.9 9.6 19.8 9.8 43.2 108.8 74.4 82.6 60.9 15.1 28.5 48.1 126.9 25.8 37.3 23.9 0.0 49.6 27.9 23.5 168.3 37.7 3.3 19.2 18.3 30.7 39.3 23.3 18.5 27.6 47.6 34.4 33.6 15.9 20.3 42.5 26.0 51.8 53.9 26.9 17.8 44.3 67.1 18.3 33.7 6.2 26.1 20.2 55.2 11.2 19.7 20.7 24.7 8.0 13.1 21.4 19.7 24.8 40.6 63.7 24.2 118.0 16.6 16.6 26.3 57.8 49.1 42.3 63.7 63.1 96.7 32.8 34.3 43.4 58.1 46.4 NDUFAF5 "C20orf7, dJ842G6.1" ENSG00000101247 "NADH:ubiquinone oxidoreductase complex assembly factor 5" Q5TEU4 20 13785007-13821580 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Oxidoreductase, Transferase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 20.5" "Cell type enhanced" "Detected in many" "Early spermatids: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051184 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA051184: AB_2681377" "unprognostic (3.81e-1)" "unprognostic (1.27e-2)" "unprognostic (4.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (8.22e-2)" "unprognostic (1.68e-2)" "unprognostic (3.14e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (1.74e-3)" "unprognostic (2.41e-2)" "prognostic favorable (2.27e-6)" "unprognostic (5.38e-2)" "unprognostic (5.89e-2)" "unprognostic (6.88e-2)" "unprognostic (1.58e-2)" 3.2 3.8 4.3 1.2 4.2 5.9 3.0 4.8 5.0 2.8 4.1 5.1 3.6 3.2 0.9 3.1 2.7 1.5 10.4 4.2 4.0 5.0 4.8 2.6 1.5 3.8 3.7 2.2 2.5 4.4 3.4 2.1 4.0 3.3 2.6 3.7 2.9 1.9 20.5 3.4 3.1 3.0 3.5 2.4 3.6 3.9 4.3 2.7 2.4 17.1 1.7 3.3 3.0 4.3 6.5 6.3 7.4 5.1 5.7 1.7 3.7 4.6 3.6 6.0 5.0 13.8 4.7 10.8 4.6 4.9 11.3 8.6 13.9 9.1 4.9 5.1 8.0 9.6 3.9 16.8 7.3 8.6 4.7 3.4 6.4 7.3 4.8 2.6 5.2 10.2 7.6 5.2 5.9 8.4 12.3 7.8 2.6 7.3 6.7 8.1 9.1 6.6 6.8 8.5 7.4 7.5 5.0 13.5 15.0 2.4 6.8 6.0 5.6 7.1 3.6 6.0 7.4 5.7 9.2 8.7 3.1 3.6 7.4 1.2 2.1 4.0 2.4 2.7 1.7 2.5 2.0 1.6 3.0 2.2 2.3 2.3 0.5 3.5 1.9 3.6 2.4 1.1 4.3 4.2 4.8 5.0 4.2 4.0 3.8 3.7 4.0 3.5 4.3 4.3 9.0 0.0 11.2 18.3 8.3 6.2 8.6 15.1 6.8 46.6 6.5 10.4 42.4 4.3 7.4 11.0 27.1 15.9 12.4 8.6 29.4 12.1 68.2 6.5 8.8 8.7 12.5 3.4 27.0 5.6 8.4 10.5 13.3 7.3 7.6 15.9 3.9 11.4 14.0 11.8 29.3 14.1 22.4 8.8 5.9 12.7 6.8 7.7 1.8 12.2 7.9 13.9 13.4 20.6 19.3 9.8 6.2 12.4 8.8 8.9 12.8 33.1 7.4 25.0 0.0 8.8 18.0 35.9 26.7 9.9 7.4 14.6 10.7 18.5 11.7 12.9 NDUFAF6 "C8orf38, MGC40214" ENSG00000156170 "NADH:ubiquinone oxidoreductase complex assembly factor 6" Q330K2 8 94895767-95116455 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047148, HPA050545" Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA047148: AB_2679954, HPA050545: AB_2681166" "unprognostic (1.97e-3)" "unprognostic (1.62e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (8.73e-2)" "unprognostic (3.45e-2)" "unprognostic (7.62e-3)" "unprognostic (2.52e-2)" "unprognostic (9.61e-2)" "unprognostic (3.85e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-3)" "unprognostic (9.44e-2)" "unprognostic (1.57e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-3)" 4.7 3.1 6.9 4.1 7.7 5.5 5.3 8.8 8.1 1.9 5.1 4.4 2.1 3.2 5.7 4.3 4.2 1.9 8.8 6.4 7.8 4.4 10.9 2.6 4.9 6.9 7.6 3.9 3.1 3.5 2.6 3.6 7.3 3.5 5.5 7.4 2.2 3.4 14.6 5.6 3.0 3.2 6.7 3.1 4.3 4.0 7.6 4.7 6.3 13.8 5.2 2.5 1.7 8.9 7.7 4.5 5.4 5.1 3.5 4.3 11.1 8.0 5.0 6.6 4.8 3.6 3.7 14.8 5.3 3.7 2.0 6.3 7.8 5.4 4.9 3.7 15.1 13.7 10.0 6.7 5.4 5.1 6.9 6.5 9.0 3.8 6.1 3.0 3.8 12.1 9.9 8.0 8.0 6.8 13.0 16.5 5.9 10.0 10.6 8.6 4.3 11.3 6.1 7.3 10.1 5.5 4.1 2.5 10.8 6.5 10.1 4.2 4.8 4.7 3.7 3.7 5.8 10.7 8.5 12.4 3.9 13.5 2.7 1.9 1.8 3.0 2.3 1.1 2.9 5.8 3.2 2.2 2.4 5.4 3.1 2.3 0.9 2.9 2.2 2.1 2.9 1.9 6.9 7.7 8.8 8.1 6.4 7.8 6.9 7.6 7.3 6.7 7.6 8.9 23.4 12.8 15.9 35.3 23.6 9.7 10.1 21.5 19.4 22.7 25.7 27.4 32.0 28.6 21.2 12.9 16.7 24.0 14.3 18.5 43.0 15.8 28.5 13.5 9.1 14.8 12.5 23.3 31.8 34.7 30.2 9.4 10.7 9.8 31.8 21.5 12.1 28.3 22.6 25.2 37.0 15.3 24.4 7.3 5.6 8.1 10.5 10.1 14.2 33.7 12.0 25.6 6.2 43.2 58.3 19.3 18.2 13.9 53.1 11.2 23.2 38.2 24.7 23.6 13.1 11.9 21.4 28.4 43.9 17.9 11.9 10.9 13.0 16.5 19.4 9.5 NDUFB1 "CI-MNLL, MNLL" ENSG00000183648 "NADH:ubiquinone oxidoreductase subunit B1" O75438 14 92116122-92121917 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2435.4;Hepatocytes: 1690.0;Proximal tubular cells: 1614.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063737 Supported Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "Nuclear speckles" "HPA063737: AB_2685109" "unprognostic (1.12e-2)" "unprognostic (1.31e-3)" "unprognostic (6.70e-2)" "unprognostic (2.67e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-2)" "unprognostic (6.91e-2)" "unprognostic (3.74e-3)" "unprognostic (5.35e-3)" "unprognostic (4.55e-3)" "unprognostic (1.18e-2)" "unprognostic (4.15e-2)" "prognostic favorable (1.31e-5)" "unprognostic (7.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.05e-3)" 260.8 396.4 370.4 109.0 381.4 167.4 231.8 388.5 588.6 178.3 409.2 313.4 165.7 164.9 178.3 281.5 177.1 61.2 1221.5 381.0 401.1 512.7 503.2 182.3 118.4 379.8 374.6 162.7 206.3 373.5 314.7 61.1 383.2 221.5 122.4 260.9 233.5 59.5 862.6 153.6 225.9 69.4 381.2 214.0 292.4 112.3 376.4 230.6 250.4 1053.8 106.1 192.1 202.4 391.0 198.3 388.3 332.5 208.4 219.1 160.7 143.0 243.2 143.7 147.5 135.4 236.9 341.0 187.0 215.7 151.3 205.8 249.6 198.4 212.3 133.9 280.8 425.1 361.3 665.8 308.5 178.2 290.4 196.4 202.5 132.0 159.5 140.7 334.8 136.7 353.7 199.0 370.1 211.8 759.0 286.6 250.0 166.4 779.6 492.1 253.3 309.7 274.2 397.7 491.3 210.8 152.8 486.6 289.7 338.3 277.7 432.0 435.0 291.8 89.3 173.0 181.3 161.7 288.4 477.2 422.0 278.4 208.5 187.9 456.1 566.8 447.5 247.4 409.6 288.5 373.7 361.5 286.0 508.6 306.8 355.4 343.9 721.3 296.6 386.6 604.6 438.9 653.6 370.4 381.4 388.5 588.6 381.0 401.1 379.8 374.6 383.2 381.2 376.4 391.0 158.5 166.7 227.4 11.4 187.4 128.7 102.1 334.5 96.8 84.6 328.2 353.6 2435.4 467.5 237.0 389.9 39.6 260.3 170.4 627.2 1166.1 245.4 175.8 326.0 208.6 188.2 317.4 256.1 18.4 427.7 118.8 203.6 189.6 225.8 215.8 96.2 397.3 1690.0 422.3 55.5 21.7 515.9 268.5 619.8 179.3 57.3 262.5 281.7 332.6 10.3 478.1 223.3 241.0 11.1 15.0 294.4 628.7 241.1 201.6 97.9 845.2 1614.3 337.6 183.3 223.5 172.4 188.2 138.8 151.5 204.5 176.2 205.8 163.7 97.4 540.6 116.3 NDUFB2 "AGGG, CI-AGGG" ENSG00000090266 "NADH:ubiquinone oxidoreductase subunit B2" O95178 7 140690777-140722790 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3191.4;Distal tubular cells: 1997.6;Proximal tubular cells: 2437.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051377 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Mitochondria "HPA051377: AB_2681460" "unprognostic (1.17e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-1)" "unprognostic (4.83e-2)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.20e-2)" "unprognostic (3.30e-2)" "unprognostic (8.30e-2)" "unprognostic (1.95e-3)" "unprognostic (4.35e-3)" "unprognostic (1.23e-1)" "prognostic favorable (7.60e-7)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" 187.2 225.3 347.4 123.4 363.9 143.1 159.9 377.3 441.6 142.0 374.0 239.9 166.0 153.4 171.5 196.9 129.6 141.8 847.4 343.6 369.1 420.0 281.2 140.1 164.8 359.0 355.8 108.0 159.4 362.6 182.3 105.9 361.1 152.0 183.0 175.9 197.6 152.3 834.7 152.0 161.1 154.8 369.8 155.1 216.4 125.5 378.3 162.3 350.5 913.1 134.0 186.6 145.5 377.6 322.5 497.0 182.1 400.9 291.9 297.5 259.9 227.0 207.6 241.4 229.1 389.7 317.3 243.1 331.7 289.9 441.7 155.4 167.0 333.4 194.1 399.5 556.9 179.1 442.3 461.3 230.0 279.2 231.0 331.6 287.5 227.0 138.2 201.3 368.1 338.8 311.2 289.9 343.2 945.8 448.2 719.4 424.0 670.0 585.0 251.1 174.6 569.4 492.0 634.2 369.0 359.3 310.4 513.8 281.0 205.7 222.9 315.7 295.2 307.0 179.2 365.6 401.5 267.6 567.2 457.2 469.0 447.7 395.8 713.9 1045.5 503.4 779.4 1117.0 673.3 1009.8 755.0 768.2 1161.9 787.8 800.5 793.7 85.6 823.9 1037.9 926.9 772.0 1795.1 347.4 363.9 377.3 441.6 343.6 369.1 359.0 355.8 361.1 369.8 378.3 377.6 262.7 189.1 238.4 25.5 191.1 226.5 289.3 693.4 128.1 181.9 458.3 514.8 3191.4 351.8 398.1 673.1 98.0 555.4 275.3 776.2 1997.6 373.9 901.2 294.2 298.4 283.6 428.7 143.7 19.9 314.4 466.6 327.2 307.3 366.3 280.6 212.8 205.6 1079.3 710.8 139.7 22.7 576.3 687.7 280.3 337.3 246.9 222.7 336.5 434.0 13.1 356.7 367.2 465.5 19.6 42.3 279.4 647.9 243.8 210.7 440.1 867.3 2437.9 370.2 284.1 197.2 199.2 372.0 77.0 208.6 321.9 280.6 515.0 241.7 288.6 669.6 435.8 NDUFB3 B12 ENSG00000119013 "NADH:ubiquinone oxidoreductase subunit B3" O43676 2 201071433-201085750 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 704.3;tongue: 727.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1711.2;Distal tubular cells: 1064.4;Proximal tubular cells: 780.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034596 Enhanced NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA034596: AB_10602712" "unprognostic (5.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (7.24e-4)" "unprognostic (1.41e-3)" "unprognostic (6.29e-2)" "unprognostic (8.81e-3)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-2)" "unprognostic (9.40e-3)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.27e-2)" 119.4 114.4 151.2 88.9 152.7 79.7 105.5 165.7 227.5 69.9 161.9 185.7 136.7 46.4 132.2 98.4 66.1 66.3 389.3 151.5 165.1 247.1 195.3 63.5 103.7 158.2 155.4 46.2 54.7 219.3 57.8 78.0 158.1 77.1 174.6 140.8 100.8 75.8 704.3 52.0 127.9 73.8 157.2 61.6 115.5 83.1 158.2 143.4 96.0 727.7 128.8 95.4 53.7 160.6 180.1 148.9 227.5 122.0 226.3 207.0 183.1 224.8 160.1 171.9 200.3 347.2 211.3 144.4 249.8 211.4 261.9 154.5 209.6 287.7 269.4 294.5 460.6 349.0 363.8 394.8 141.2 500.9 170.5 180.1 223.6 203.3 119.2 211.3 250.3 259.2 311.1 240.3 313.1 234.4 313.8 459.8 129.9 392.4 536.7 215.6 200.4 388.0 380.6 278.7 209.5 150.1 176.0 153.2 258.2 353.2 150.7 373.0 227.3 144.8 179.7 150.9 222.8 174.5 435.3 452.6 246.0 284.4 172.6 205.2 135.4 159.4 116.1 205.3 129.2 148.8 132.7 135.7 177.3 117.3 115.2 140.9 267.3 141.6 213.3 211.8 183.1 109.6 151.2 152.7 165.7 227.5 151.5 165.1 158.2 155.4 158.1 157.2 158.2 160.6 95.3 80.1 57.7 18.9 100.9 78.1 100.0 433.7 66.6 52.9 101.7 128.1 1711.2 141.5 205.1 187.6 12.5 254.6 83.5 473.9 1064.4 247.0 218.1 191.6 93.9 101.9 146.4 113.8 13.2 201.7 208.9 103.4 118.7 135.2 78.0 61.0 86.7 260.5 288.2 32.0 14.7 299.0 248.2 121.6 107.1 59.9 95.4 126.8 168.9 10.3 292.9 184.6 116.4 7.5 19.9 177.3 411.0 101.5 135.2 72.5 496.3 780.3 229.2 92.0 92.1 82.3 125.4 270.0 89.7 169.2 91.9 157.6 89.7 113.9 322.1 132.9 NDUFB4 B15 ENSG00000065518 "NADH:ubiquinone oxidoreductase subunit B4" O95168 3 120596328-120602507 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 945.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1493.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051739, HPA064441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Nuclear membrane" "HPA051739: AB_2681585, HPA064441: " "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.95e-2)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.35e-3)" "unprognostic (9.66e-3)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (3.69e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "prognostic favorable (1.79e-4)" 148.6 338.4 159.7 90.3 169.1 112.4 145.1 175.9 203.2 126.2 173.2 170.0 147.8 117.9 133.8 159.5 113.0 85.7 619.5 163.5 178.4 232.4 187.4 102.9 93.8 168.3 163.0 119.8 137.4 260.3 170.2 76.8 168.6 118.1 148.7 100.2 148.4 117.4 945.3 144.5 135.6 103.4 170.7 112.1 162.3 106.5 161.7 125.6 113.1 562.2 114.2 133.5 142.1 172.8 294.8 204.3 246.7 248.5 151.0 181.4 199.2 157.0 212.1 205.4 224.5 200.9 219.8 147.8 311.6 177.8 255.6 272.5 191.3 202.7 155.7 227.5 212.6 226.1 205.7 208.1 90.4 202.7 256.8 161.3 268.5 98.9 125.8 246.0 258.5 271.7 138.5 219.2 220.9 224.1 398.6 294.8 193.9 478.9 554.7 228.8 141.0 325.8 337.3 177.9 273.8 283.4 186.5 205.7 360.0 162.0 348.0 319.9 199.8 179.0 233.2 76.9 226.5 263.2 260.1 454.3 283.6 279.8 250.8 205.0 164.8 197.2 156.0 229.5 162.2 231.6 215.2 176.8 213.9 176.3 182.2 181.8 101.6 152.7 238.2 267.9 300.6 205.7 159.7 169.1 175.9 203.2 163.5 178.4 168.3 163.0 168.6 170.7 161.7 172.8 274.1 163.5 162.6 36.9 167.0 222.3 289.0 612.6 190.6 137.8 290.1 351.3 1493.1 311.7 348.3 320.0 58.4 366.0 158.1 472.4 1226.7 556.7 999.2 259.9 188.9 235.7 298.7 196.9 22.6 620.9 421.0 213.7 175.3 293.5 174.8 139.4 183.5 513.9 330.3 84.1 22.0 526.3 451.6 240.2 247.9 164.6 275.2 196.2 434.0 15.9 339.2 340.7 186.4 13.0 31.2 567.9 581.8 277.2 283.2 243.2 613.4 1225.1 266.2 168.4 256.4 208.1 259.0 418.9 87.5 288.4 251.5 352.4 168.1 271.3 462.8 344.0 NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 583.9;Distal tubular cells: 534.1;Early spermatids: 889.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044001, HPA053334" Supported Enhanced Mitochondria No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA044001: AB_10959448, HPA053334: AB_2682116" "unprognostic (4.09e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.81e-2)" "unprognostic (1.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-3)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.47e-10)" "unprognostic (2.70e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" 38.6 50.8 42.7 30.7 45.3 31.0 35.9 47.1 48.1 34.1 42.8 41.8 44.6 38.1 26.8 43.8 36.0 17.6 144.9 44.5 46.5 73.6 66.7 30.5 26.9 44.5 42.9 29.7 31.0 41.8 40.3 22.5 44.6 28.5 29.1 30.7 37.0 22.0 168.0 28.2 43.6 26.7 45.9 28.8 43.5 53.5 44.3 28.7 33.2 101.8 24.5 34.1 33.4 47.1 106.4 63.7 69.6 80.1 46.7 43.0 44.5 69.5 56.5 62.8 68.8 62.8 46.5 78.4 70.5 48.2 65.1 58.8 66.5 76.8 47.0 108.6 106.0 187.2 88.8 65.9 45.2 94.4 46.3 44.8 36.7 56.8 42.9 47.5 57.6 118.4 61.0 86.1 71.9 61.2 128.1 221.2 73.6 90.7 140.1 86.7 58.4 73.1 72.0 39.3 69.7 78.4 80.2 91.1 50.7 52.0 86.3 72.0 51.4 67.9 103.8 75.7 103.8 38.0 77.0 131.5 113.7 65.6 32.7 126.3 97.6 136.1 76.9 94.3 74.5 106.0 81.4 80.0 108.8 89.0 82.3 87.4 302.1 91.9 116.3 152.7 112.4 110.2 42.7 45.3 47.1 48.1 44.5 46.5 44.5 42.9 44.6 45.9 44.3 47.1 69.5 125.0 111.6 15.3 76.2 94.2 106.2 222.9 90.0 44.1 64.6 72.6 583.9 101.5 141.4 108.5 6.2 191.8 69.4 115.8 534.1 172.5 889.5 106.9 86.1 101.0 64.6 196.7 21.8 166.7 143.0 109.5 83.6 86.4 90.5 64.3 74.3 182.2 160.8 18.5 23.8 152.5 209.5 55.0 96.4 146.9 91.6 78.4 160.1 3.7 108.6 115.3 90.6 18.1 21.3 144.4 124.9 89.9 165.7 80.0 201.0 520.3 152.3 56.5 105.2 94.8 151.3 182.0 125.9 139.7 96.7 104.1 81.0 95.6 167.3 103.8 NDUFB7 "B18, CI-B18, MGC2480" ENSG00000099795 "NADH:ubiquinone oxidoreductase subunit B7" P17568 19 14566078-14572066 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002817 Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002817: AB_1079462" "unprognostic (2.80e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.03e-1)" "unprognostic (4.09e-2)" "unprognostic (4.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.95e-1)" "unprognostic (1.45e-3)" "unprognostic (2.07e-1)" "unprognostic (1.87e-2)" "unprognostic (2.02e-2)" "unprognostic (4.14e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.40e-1)" "unprognostic (1.69e-1)" "unprognostic (1.59e-1)" "unprognostic (9.25e-3)" 203.1 216.1 209.9 66.1 218.4 103.7 188.8 232.4 325.4 153.6 216.5 256.3 124.6 169.4 51.1 230.7 152.3 57.7 695.8 204.8 222.5 291.7 335.7 127.8 70.4 222.2 221.3 137.3 213.5 143.2 182.8 61.6 218.9 171.0 55.9 28.6 198.7 93.2 709.4 189.4 163.2 50.6 213.2 150.0 231.9 132.8 230.2 50.6 189.7 266.9 39.5 167.3 161.2 222.6 242.1 237.4 95.0 203.1 80.4 80.5 167.4 110.1 120.6 200.0 189.2 317.9 130.2 109.4 322.0 102.9 87.5 185.0 62.6 241.1 26.7 170.1 320.8 212.2 380.9 334.6 142.1 138.7 141.5 131.7 196.6 105.7 49.6 56.1 161.7 194.9 132.9 194.8 94.2 452.7 227.0 308.0 242.4 228.1 773.2 174.3 112.8 264.6 143.0 253.3 204.4 217.6 114.9 265.6 303.4 24.6 175.0 245.1 122.0 253.5 123.2 324.4 207.0 264.4 295.5 144.1 243.7 267.8 174.5 355.6 414.5 140.4 432.9 395.5 403.8 368.6 291.4 368.9 415.4 327.7 241.3 315.5 119.4 422.4 389.5 460.4 373.3 562.3 209.9 218.4 232.4 325.4 204.8 222.5 222.2 221.3 218.9 213.2 230.2 222.6 196.4 76.9 95.9 19.9 155.6 133.4 177.9 358.5 126.9 117.4 285.4 363.9 670.4 245.9 214.2 259.3 56.3 359.7 155.5 937.3 1154.3 324.9 81.8 162.8 133.9 163.5 332.1 152.9 7.4 455.3 330.5 185.2 194.7 152.1 102.2 197.4 203.1 589.1 377.5 72.3 11.4 639.3 299.1 237.9 158.0 252.0 207.5 173.9 378.8 10.3 327.3 236.4 365.6 8.5 25.5 367.9 720.8 200.1 197.5 175.4 916.4 1041.9 193.1 152.4 236.7 193.6 330.8 133.7 252.1 235.7 161.2 225.6 138.6 197.5 631.6 220.1 NDUFB8 "ASHI, CI-ASHI" ENSG00000166136 "NADH:ubiquinone oxidoreductase subunit B8" O95169 10 100523740-100530000 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 876.5;Proximal tubular cells: 881.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA003886, HPA065549" Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA003886: AB_1079463, HPA065549: " "unprognostic (4.07e-2)" "unprognostic (1.95e-3)" "unprognostic (2.28e-1)" "unprognostic (7.33e-2)" "unprognostic (4.88e-2)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (6.46e-2)" "unprognostic (8.33e-2)" "unprognostic (9.09e-2)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-2)" 152.6 199.3 431.2 103.4 439.3 171.5 135.8 427.1 606.3 127.3 416.7 237.8 161.0 145.8 163.0 170.2 132.4 88.0 482.4 444.8 441.9 249.9 262.0 108.6 132.0 438.5 439.4 130.4 115.5 331.0 186.7 83.0 441.9 132.2 145.0 127.1 163.6 135.8 408.9 128.2 147.8 125.5 411.8 133.3 201.0 66.2 442.5 140.6 130.1 512.8 119.9 162.9 132.9 448.3 250.2 419.6 222.3 383.1 159.6 158.8 238.5 168.1 370.9 259.3 278.8 575.4 278.1 260.7 146.4 185.6 189.1 289.5 162.9 269.7 194.5 172.9 417.8 183.9 350.3 465.7 217.6 379.3 302.6 191.6 240.7 249.2 329.3 180.4 283.7 361.1 194.5 159.3 218.4 304.1 369.7 472.9 144.7 324.3 377.9 252.4 237.6 346.1 298.8 281.3 147.9 209.7 122.0 227.4 250.9 147.3 338.2 332.8 185.5 139.5 158.7 151.5 296.8 288.4 286.4 334.8 277.6 398.2 159.3 299.4 530.8 478.1 406.0 558.8 483.1 616.1 498.0 468.1 589.7 546.7 538.1 514.0 122.7 478.0 489.6 655.0 817.6 1113.4 431.2 439.3 427.1 606.3 444.8 441.9 438.5 439.4 441.9 411.8 442.5 448.3 184.8 76.9 132.7 41.8 107.6 0.0 187.1 0.0 12.5 186.4 162.2 210.2 392.9 204.5 48.3 198.6 58.4 333.1 175.8 109.0 876.5 268.1 24.9 105.8 86.3 142.7 105.6 114.3 72.6 264.7 305.1 128.8 35.2 87.1 109.7 112.0 153.8 346.5 399.1 153.1 82.6 171.6 0.0 184.4 0.0 56.0 218.1 142.2 0.0 33.7 231.0 219.5 158.6 40.2 62.3 250.6 191.7 217.4 59.3 203.2 560.2 881.6 85.2 183.5 170.9 117.2 176.0 85.5 83.1 31.5 0.0 307.7 112.9 225.5 237.6 221.5 NDUFB9 "B22, LYRM3, UQOR22" ENSG00000147684 "NADH:ubiquinone oxidoreductase subunit B9" Q9Y6M9 8 124539101-124580648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1314.9;tongue: 1486.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 2950.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042768 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA042768: AB_10797508" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-3)" "unprognostic (8.32e-2)" "unprognostic (9.71e-2)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (3.80e-2)" "unprognostic (1.51e-1)" "unprognostic (3.64e-1)" "prognostic favorable (3.42e-5)" "unprognostic (9.54e-2)" "unprognostic (9.64e-2)" "unprognostic (4.94e-2)" "unprognostic (2.74e-1)" 155.6 158.2 259.0 78.5 263.8 265.2 157.8 281.1 381.2 109.7 245.0 226.4 184.6 129.5 147.4 209.2 126.0 70.4 789.5 257.6 288.7 324.9 325.0 122.9 96.5 279.3 277.8 107.1 209.4 282.9 124.0 81.2 281.5 117.8 191.0 135.8 210.9 115.1 1314.9 149.3 162.9 111.1 253.4 116.8 241.2 204.7 286.2 102.8 154.2 1486.4 104.1 139.9 124.7 274.1 348.2 316.8 236.1 321.2 240.6 204.2 196.0 165.2 189.3 297.4 222.4 417.7 327.6 341.0 421.0 193.6 153.9 385.5 347.3 266.7 279.9 395.8 464.8 831.3 199.6 505.9 320.8 261.8 218.2 239.6 382.1 271.9 587.9 160.1 275.9 241.1 523.7 277.6 243.4 1089.0 415.8 522.7 237.5 1247.0 692.7 276.3 179.9 468.0 400.0 288.8 326.6 255.0 362.4 2950.7 382.8 141.1 407.3 348.2 219.7 172.5 444.1 162.9 399.5 354.8 517.7 392.5 298.6 515.4 233.1 302.2 253.1 136.2 210.5 179.2 209.6 260.9 275.8 237.1 247.5 201.4 269.1 223.9 49.2 188.9 136.1 183.1 346.0 345.8 259.0 263.8 281.1 381.2 257.6 288.7 279.3 277.8 281.5 253.4 286.2 274.1 169.0 125.0 124.8 7.8 147.7 217.8 277.5 448.3 178.7 77.4 247.3 313.0 1005.6 260.2 267.3 286.9 98.0 494.6 119.9 525.0 800.3 338.0 389.8 120.7 100.6 164.1 233.7 227.6 10.5 405.7 296.0 187.9 169.7 109.2 139.4 149.9 167.4 517.7 380.6 37.0 14.9 421.0 488.3 206.0 137.6 865.4 158.8 183.0 247.3 15.9 226.3 144.1 171.0 7.1 18.2 378.1 450.0 152.7 169.1 290.3 584.6 789.7 208.6 91.1 170.9 221.2 511.8 317.6 264.8 377.0 188.4 523.0 155.6 216.0 521.7 315.8 NDUFS3 CI-30 ENSG00000213619 "NADH:ubiquinone oxidoreductase core subunit S3" O75489 11 47565336-47584562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 292.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 405.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004484, CAB034894" Enhanced Supported "Nuclear bodies,Mitochondria" NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nuclear bodies" "CAB034894: AB_2151118, HPA004484: AB_1079464" "unprognostic (2.18e-1)" "unprognostic (7.42e-3)" "unprognostic (1.75e-1)" "unprognostic (5.01e-2)" "unprognostic (7.51e-2)" "unprognostic (3.13e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "unprognostic (1.93e-1)" "unprognostic (1.41e-2)" "unprognostic (6.75e-3)" "unprognostic (7.73e-2)" "prognostic favorable (2.61e-6)" "unprognostic (2.77e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-2)" "unprognostic (3.17e-3)" 52.4 91.3 47.4 16.5 52.6 44.1 50.7 55.6 50.2 43.5 59.4 97.5 53.8 49.7 26.2 78.7 42.6 18.1 210.3 49.3 51.9 94.2 96.2 40.5 25.5 48.8 49.3 37.3 56.7 53.6 67.5 17.6 49.4 44.0 52.7 23.5 60.9 27.5 292.3 66.2 69.4 26.6 50.3 55.5 81.4 48.2 54.7 33.8 49.7 194.2 33.3 51.4 52.0 47.7 37.7 68.7 59.8 62.9 48.8 52.3 48.2 35.0 60.3 84.6 80.4 103.6 65.1 81.8 34.8 49.7 63.0 64.9 81.7 61.8 69.4 44.2 137.2 49.5 90.6 106.5 49.7 121.5 62.1 50.1 46.6 32.0 52.2 37.5 55.3 69.2 73.7 57.1 57.7 118.6 87.0 164.9 83.6 109.6 97.7 100.7 81.8 68.7 76.4 60.2 63.9 47.1 43.4 76.9 83.5 35.2 84.4 118.2 37.0 49.3 56.4 57.0 80.4 61.2 93.5 91.8 50.1 94.9 51.3 38.3 69.3 48.9 43.2 79.8 46.4 60.6 45.2 47.5 83.3 59.2 42.4 46.0 18.4 45.6 66.7 89.3 61.3 90.3 47.4 52.6 55.6 50.2 49.3 51.9 48.8 49.3 49.4 50.3 54.7 47.7 54.7 54.5 42.6 23.5 54.6 65.6 67.4 217.5 62.6 45.6 60.2 72.5 176.9 81.5 108.5 69.9 41.7 122.0 70.8 183.1 405.0 113.0 132.3 56.8 58.6 60.0 84.7 73.8 12.7 111.3 116.5 60.8 81.1 40.5 57.7 67.1 58.5 126.3 195.9 60.6 14.5 162.8 173.0 66.9 59.3 63.2 67.4 62.8 119.2 7.5 83.9 117.9 58.7 12.5 13.1 91.7 109.3 69.2 69.8 53.0 257.8 297.0 109.7 59.5 105.2 55.5 154.8 85.5 74.7 115.3 75.9 89.1 55.5 128.3 210.7 85.3 NDUFS5 CI-15k ENSG00000168653 "NADH:ubiquinone oxidoreductase subunit S5" O43920 1 39026318-39034636 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2057.9;Proximal tubular cells: 1739.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042582 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA042582: AB_2678062" "unprognostic (1.49e-2)" "unprognostic (2.62e-2)" "unprognostic (3.58e-1)" "unprognostic (1.41e-2)" "unprognostic (5.00e-2)" "unprognostic (2.93e-2)" "unprognostic (2.97e-3)" "unprognostic (8.96e-2)" "unprognostic (7.31e-2)" "prognostic favorable (3.54e-4)" "unprognostic (1.29e-1)" "unprognostic (7.07e-2)" "unprognostic (2.40e-1)" "unprognostic (7.87e-3)" "unprognostic (2.88e-1)" "unprognostic (2.52e-3)" "unprognostic (8.08e-2)" 343.8 373.0 538.9 184.4 542.6 266.0 296.9 532.6 830.4 253.2 515.0 461.2 220.1 315.4 565.3 363.3 265.7 167.1 1277.8 542.3 540.7 399.5 379.3 236.9 176.8 552.2 538.3 304.8 234.1 354.2 333.3 170.2 541.7 292.4 342.3 206.7 274.1 299.5 954.0 284.9 240.5 259.4 524.1 185.2 339.9 121.3 543.4 240.1 250.6 1115.6 245.5 322.3 273.9 568.5 447.7 781.3 548.2 698.8 593.9 622.8 749.7 501.6 406.3 488.6 490.3 868.9 596.3 469.0 700.2 541.6 248.9 308.9 732.5 688.3 543.1 546.2 856.8 491.8 1291.1 1622.7 407.4 1015.6 366.8 650.5 816.8 537.4 476.0 497.3 858.3 500.8 817.0 430.9 250.4 1030.4 468.4 1291.3 1000.5 654.5 785.8 648.7 815.5 806.7 1027.9 1482.9 741.7 710.6 583.9 773.6 712.8 1174.2 520.2 753.1 545.7 390.9 463.1 409.8 874.3 353.5 770.5 732.6 449.7 1110.5 567.4 186.2 264.6 159.6 227.6 293.9 262.8 196.4 353.2 268.4 275.3 158.3 359.9 316.3 51.7 205.9 282.5 340.5 361.7 341.2 538.9 542.6 532.6 830.4 542.3 540.7 552.2 538.3 541.7 524.1 543.4 568.5 260.1 166.7 196.0 16.6 197.1 460.9 390.6 958.6 187.2 128.6 337.9 400.8 2057.9 391.7 407.6 551.8 37.5 638.9 248.2 570.5 1367.6 581.1 134.7 487.4 454.0 288.4 407.8 230.8 17.0 543.4 647.0 377.8 246.2 508.5 209.8 544.6 271.6 638.8 545.9 99.3 18.7 652.0 539.1 298.1 385.5 121.4 351.9 297.5 457.2 10.3 361.8 307.3 207.0 13.6 24.0 609.1 517.7 422.8 247.6 484.1 576.2 1739.7 343.3 180.6 282.7 417.4 450.5 121.8 99.2 418.8 460.3 525.2 292.2 275.9 697.1 454.2 NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 833.5;Late spermatids: 797.2;Proximal tubular cells: 927.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA018524: AB_1854355, HPA067429: " "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" 99.2 308.4 141.2 38.8 153.2 56.2 87.7 157.2 180.4 73.2 172.3 142.0 81.4 89.2 27.2 115.3 81.3 29.1 468.2 144.2 152.0 188.6 152.0 73.1 42.2 149.6 144.9 68.2 97.7 74.6 130.6 33.6 145.8 118.2 36.7 49.5 96.2 66.7 406.4 93.0 84.4 39.0 142.2 76.9 137.8 104.7 154.0 40.3 101.8 275.5 30.1 94.4 76.0 150.2 152.9 366.4 94.6 137.0 70.9 63.5 132.4 102.3 88.5 155.6 118.9 338.4 159.6 118.4 186.8 85.9 134.6 181.2 108.8 128.4 53.1 139.4 264.9 107.2 217.1 186.3 171.8 99.1 112.1 80.5 126.5 111.1 124.8 82.0 106.2 159.9 110.3 121.1 99.2 358.6 219.2 216.9 125.2 377.7 308.0 154.4 95.9 384.9 192.8 123.3 125.5 102.2 75.7 171.7 392.3 66.5 245.6 105.9 84.1 155.6 133.9 224.8 148.8 165.2 188.5 99.7 252.3 121.8 111.2 84.7 220.1 124.0 182.4 232.0 170.1 183.3 154.6 165.5 309.4 156.3 146.2 164.2 20.7 309.6 131.7 324.3 202.2 232.4 141.2 153.2 157.2 180.4 144.2 152.0 149.6 144.9 145.8 142.2 154.0 150.2 88.7 89.8 90.1 18.6 92.3 85.4 95.5 284.3 104.7 83.4 147.2 156.7 301.9 143.0 164.9 213.3 54.2 279.6 97.8 301.0 833.5 200.8 225.7 101.1 74.8 85.3 205.0 149.8 13.6 199.3 165.9 109.6 147.3 79.7 95.8 156.5 73.5 231.7 276.6 50.5 19.3 277.2 240.1 124.1 108.0 797.2 100.6 128.7 163.7 13.1 187.4 143.6 128.8 12.1 15.4 173.7 194.9 108.0 157.8 118.6 337.1 927.8 120.8 118.7 59.2 81.2 208.6 105.9 72.7 209.7 116.2 172.4 102.7 278.7 318.2 139.1 NECAB3 "APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51" ENSG00000125967 "N-terminal EF-hand calcium binding protein 3" Q96P71 20 33657087-33674463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 93.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044785, HPA070595, HPA071786" Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA044785: AB_2679086, HPA070595: AB_2732158, HPA071786: AB_2732186" "unprognostic (8.95e-2)" "unprognostic (1.45e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.44e-1)" "unprognostic (4.05e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.19e-5)" "unprognostic (3.13e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (6.13e-2)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-1)" 10.2 55.9 20.1 2.2 21.2 1.5 10.4 18.9 33.9 11.8 20.4 14.4 13.6 9.1 6.9 8.9 10.9 4.5 45.7 21.7 21.2 13.3 13.3 11.1 2.3 23.3 19.1 41.2 19.1 17.5 10.3 3.9 24.4 27.2 4.4 6.5 13.6 7.8 60.3 6.9 10.6 3.7 16.6 6.5 30.5 10.6 23.2 1.9 19.2 31.7 1.7 14.6 10.0 22.3 8.2 7.1 5.1 10.5 4.0 7.8 24.6 11.2 4.2 7.1 6.2 33.2 5.3 9.1 26.2 6.6 16.7 9.7 5.3 3.3 2.6 3.2 7.7 8.7 30.7 39.3 10.5 2.1 8.0 9.7 4.8 6.6 2.1 7.6 4.8 4.8 12.6 4.8 9.3 12.5 3.3 8.6 2.2 8.7 17.5 9.7 13.3 15.9 6.6 6.1 32.4 9.0 26.1 28.7 12.0 5.6 36.6 10.4 4.0 8.6 12.4 11.3 12.7 17.7 7.8 17.1 16.9 4.0 3.8 0.0 1.3 1.8 0.3 1.3 0.9 0.2 0.6 0.3 1.2 0.9 0.4 0.1 0.0 1.2 3.5 0.0 1.6 0.6 20.1 21.2 18.9 33.9 21.7 21.2 23.3 19.1 24.4 16.6 23.2 22.3 5.4 16.0 45.5 14.7 4.1 3.1 6.5 2.7 8.6 19.4 20.5 11.6 29.9 10.0 5.9 5.5 8.4 20.6 3.8 22.5 33.2 3.7 93.1 5.7 7.2 2.4 19.9 4.0 13.0 7.5 26.1 12.5 26.5 5.4 3.8 14.0 2.2 9.1 8.9 8.4 14.5 16.2 4.1 6.0 6.2 54.0 26.4 5.5 12.4 1.0 3.6 18.2 2.1 6.0 4.5 4.4 15.1 23.7 11.7 14.2 45.9 12.2 3.8 20.8 6.6 9.2 12.1 20.5 20.6 9.3 3.1 20.7 5.4 23.9 20.0 10.0 NEDD8 Nedd-8 ENSG00000129559 "NEDD8 ubiquitin like modifier" Q15843 14 24216857-24232367 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004082, HPA027583, HPA060254" Uncertain Enhanced Nucleoplasm,Cytosol NA NA 990000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Cytosol "CAB004082: AB_10695300, HPA027583: AB_2732439, HPA060254: AB_2732644" "unprognostic (1.26e-2)" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.34e-3)" "unprognostic (1.83e-3)" "unprognostic (9.19e-2)" "unprognostic (4.66e-1)" "unprognostic (1.35e-2)" "unprognostic (2.66e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-3)" "unprognostic (2.76e-2)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (5.25e-3)" 169.0 224.3 156.9 71.5 162.3 91.0 156.7 158.6 219.1 152.4 152.5 172.9 55.9 147.6 132.6 202.1 131.3 51.0 299.8 163.1 168.6 195.8 175.7 147.7 81.2 163.7 158.7 138.1 110.9 289.1 143.9 84.3 162.4 133.7 88.7 74.6 139.3 85.5 294.3 182.2 128.8 97.7 157.5 164.6 146.8 77.9 162.1 125.7 132.8 197.1 113.1 152.0 157.5 162.0 166.9 292.7 223.8 159.9 255.2 223.2 165.6 218.7 237.4 259.5 237.5 204.6 196.1 142.1 126.9 317.1 212.3 169.2 230.8 349.5 365.6 201.9 139.7 150.2 272.9 710.7 220.8 251.8 151.6 237.0 231.8 217.2 172.0 239.1 317.3 162.3 139.3 161.5 409.4 380.3 203.4 241.1 166.1 303.7 335.8 141.3 176.9 146.1 302.7 322.1 96.7 221.7 188.3 192.6 168.4 229.5 117.6 199.2 230.3 145.4 144.9 184.9 198.5 187.9 322.7 210.6 102.6 146.2 139.6 461.6 277.3 459.9 214.7 302.8 235.5 311.9 246.0 241.0 276.3 273.4 229.8 233.1 299.8 233.7 310.5 369.7 327.3 526.6 156.9 162.3 158.6 219.1 163.1 168.6 163.7 158.7 162.4 157.5 162.1 162.0 276.4 144.2 156.8 0.0 182.1 277.9 227.5 644.7 166.8 101.0 263.4 301.5 464.7 215.9 301.5 310.8 47.9 525.7 237.0 267.8 594.8 344.9 72.6 201.8 189.4 259.5 212.4 220.7 0.0 406.9 625.0 246.0 108.1 195.4 218.6 228.7 222.0 431.5 576.3 106.0 0.0 286.4 362.2 288.7 345.5 77.3 272.1 255.4 268.6 0.0 394.0 275.0 346.1 0.0 0.0 449.8 311.5 275.7 161.3 254.4 340.2 845.8 279.7 95.9 210.4 178.7 318.4 150.0 196.9 252.1 386.6 419.5 216.0 289.8 291.8 275.5 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.1;Late spermatids: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 8.8 13.6 19.7 8.4 17.2 8.0 7.6 13.6 28.7 8.9 10.7 10.8 6.2 11.1 6.2 13.4 8.6 5.3 21.4 27.3 13.9 17.2 10.5 9.3 6.4 14.4 18.1 8.5 12.7 27.4 9.5 4.6 14.3 9.9 5.4 7.3 8.5 6.7 22.8 10.2 8.8 8.0 14.3 9.9 10.0 20.9 17.6 9.3 11.1 19.1 7.1 9.3 7.7 16.6 75.8 36.7 12.2 74.3 21.5 22.0 7.7 57.3 37.9 74.1 53.7 32.7 18.4 21.1 50.4 69.9 48.9 27.1 25.1 37.8 52.0 31.9 12.5 26.8 24.4 26.4 22.4 35.1 28.6 20.1 16.4 53.3 51.0 21.8 47.7 13.7 12.0 18.7 64.5 35.1 21.4 16.6 8.3 16.9 20.4 24.2 56.8 18.8 68.5 37.3 17.0 11.6 36.0 24.5 14.0 9.4 14.9 15.4 92.7 101.1 109.6 44.8 112.5 30.0 26.7 25.5 27.0 14.5 68.5 10.0 10.0 4.2 15.5 14.7 13.1 8.3 11.5 10.4 15.1 8.6 9.7 9.2 2.3 13.2 21.0 10.2 10.7 12.2 19.7 17.2 13.6 28.7 27.3 13.9 14.4 18.1 14.3 14.3 17.6 16.6 8.1 6.4 20.1 14.7 9.4 14.1 11.6 9.8 8.6 16.3 14.5 9.0 23.1 18.6 10.0 14.7 10.4 11.7 12.7 9.0 21.5 40.0 77.1 14.5 17.7 13.2 13.1 13.9 27.5 24.9 6.7 12.5 7.7 15.2 22.9 12.2 11.7 14.4 13.5 30.3 27.1 7.9 6.1 14.7 7.5 121.4 7.2 10.2 8.8 18.7 8.6 19.1 14.4 17.6 16.7 40.1 14.5 12.4 14.7 13.6 10.5 30.1 8.6 9.6 6.6 13.7 15.6 29.5 8.1 15.5 14.3 3.8 12.9 17.4 11.2 9.5 NFS1 "IscS, NifS" ENSG00000244005 "NFS1 cysteine desulfurase" Q9Y697 20 35668052-35699355 "Enzymes, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034314, HPA051801, HPA054755" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "CAB034314: AB_2235980, HPA051801: AB_2681616, HPA054755: AB_2682594" "unprognostic (1.72e-1)" "unprognostic (2.96e-1)" "unprognostic (1.27e-2)" "unprognostic (5.88e-3)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.14e-1)" "unprognostic (2.02e-1)" "unprognostic (9.00e-2)" "unprognostic (1.73e-1)" "unprognostic (6.52e-3)" "unprognostic (3.93e-2)" "prognostic favorable (4.72e-6)" "unprognostic (2.33e-2)" "unprognostic (1.97e-1)" "unprognostic (1.64e-2)" "unprognostic (5.54e-2)" 12.0 28.7 17.8 7.7 19.0 4.5 10.6 19.5 20.4 11.6 19.0 13.1 12.4 9.1 10.3 11.0 12.5 8.5 22.6 18.2 20.0 42.2 37.7 6.8 8.6 17.4 17.7 13.1 11.9 25.9 12.3 8.6 19.8 9.9 14.1 17.1 13.5 12.6 25.3 10.6 11.1 11.0 17.3 7.7 12.1 19.0 19.6 9.3 10.7 36.5 12.1 9.7 9.1 19.4 29.6 36.0 12.3 13.0 32.7 29.9 24.9 21.9 23.1 32.2 20.9 65.4 16.3 25.1 42.1 20.6 33.3 36.3 42.6 44.5 29.3 11.3 20.0 53.7 37.6 51.4 27.1 22.9 9.9 24.2 41.6 25.5 27.9 24.1 24.6 29.0 38.9 16.3 23.1 45.3 25.8 24.0 14.3 67.1 53.3 10.1 39.9 42.2 33.0 19.6 15.4 14.1 54.9 52.3 36.9 28.6 46.9 20.1 18.2 36.4 17.4 21.6 21.9 23.5 34.3 22.6 30.9 24.2 18.5 3.0 6.8 6.5 5.8 6.7 7.7 8.4 6.7 8.9 9.4 5.6 7.8 7.2 2.7 10.6 5.2 4.5 9.6 5.5 17.8 19.0 19.5 20.4 18.2 20.0 17.4 17.7 19.8 17.3 19.6 19.4 9.7 6.4 15.0 9.4 8.0 6.1 8.1 16.7 6.2 14.9 11.7 10.3 20.6 21.5 10.4 18.4 10.4 35.2 5.4 12.3 33.2 15.9 6.0 7.2 8.5 6.9 6.7 13.9 9.0 11.2 22.5 10.7 11.2 8.8 7.0 8.7 6.8 26.8 16.1 15.2 9.9 7.0 16.2 8.9 4.8 4.4 5.6 7.0 10.6 6.5 12.3 15.2 5.2 4.5 12.6 10.9 11.0 10.5 5.8 5.6 17.3 56.6 7.6 13.5 13.1 8.6 9.1 50.7 19.7 9.1 5.7 21.1 7.4 25.4 14.8 7.9 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722205-65871725 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.8;Excitatory neurons: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.6;intermediate monocyte: 3.4;myeloid DC: 2.2;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.2;monocytes: 3.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 64000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favorable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 2.2 1.0 3.8 2.4 3.9 1.5 3.7 2.9 5.3 1.8 1.6 3.6 1.1 2.7 2.4 2.5 1.5 1.2 2.6 3.8 3.6 3.9 9.9 1.7 1.7 3.9 3.4 1.8 2.5 1.5 0.9 2.4 4.0 2.6 3.2 2.5 1.9 1.1 8.9 2.8 2.7 2.7 3.3 1.3 4.0 1.1 3.9 0.9 2.7 6.5 2.0 2.7 1.5 4.8 13.3 12.5 7.2 12.0 9.0 15.3 14.5 13.1 5.5 7.6 8.2 7.2 7.7 18.8 16.1 15.8 15.1 10.3 9.5 20.2 13.1 5.6 6.4 5.2 8.7 18.5 7.7 12.0 3.0 11.7 10.8 10.5 12.4 6.3 21.7 8.3 11.4 3.9 16.5 10.2 8.3 10.8 22.2 6.7 3.6 9.6 15.3 29.9 12.6 5.9 22.3 11.5 10.6 10.7 11.0 19.4 12.9 14.1 12.5 5.0 5.9 7.4 10.0 3.3 7.1 8.2 7.7 23.2 7.7 0.1 2.6 0.1 0.1 3.4 0.1 0.4 0.2 0.1 2.2 0.4 0.3 0.2 0.3 0.5 2.3 0.1 0.0 1.0 3.8 3.9 2.9 5.3 3.8 3.6 3.9 3.4 4.0 3.3 3.9 4.8 5.9 6.4 2.8 19.6 4.0 5.7 9.0 6.2 8.6 2.4 10.1 8.9 14.5 7.2 8.5 12.9 4.2 5.3 0.6 52.8 5.9 17.8 0.3 7.4 12.9 8.3 1.8 9.0 58.9 14.5 14.0 7.1 20.4 20.9 15.2 16.2 4.6 32.4 28.8 5.0 32.2 5.8 6.1 22.9 8.9 0.4 4.4 13.5 1.8 5.6 17.9 13.1 2.1 22.6 44.5 30.2 35.9 2.2 4.9 16.5 32.3 22.4 3.1 4.7 0.0 19.7 8.1 2.1 5.2 15.3 5.3 2.9 2.3 15.8 8.2 6.1 NMNAT1 "LCA9, NMNAT, PNAT1" ENSG00000173614 "Nicotinamide nucleotide adenylyltransferase 1" Q9HAN9 1 9943428-9985501 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059447 Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA059447: AB_2684022" "unprognostic (1.94e-1)" "unprognostic (3.81e-3)" "unprognostic (7.54e-3)" "unprognostic (1.01e-1)" "unprognostic (3.50e-1)" "unprognostic (1.73e-1)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (4.45e-3)" "unprognostic (4.55e-2)" "unprognostic (1.12e-1)" "unprognostic (3.57e-1)" "prognostic favorable (3.85e-14)" "unprognostic (3.11e-3)" "unprognostic (1.17e-1)" "unprognostic (1.47e-3)" "unprognostic (5.16e-2)" 5.2 7.4 5.4 4.4 6.0 2.5 5.7 4.8 7.7 5.4 9.2 9.0 6.0 3.8 5.8 5.2 4.8 3.4 10.7 5.1 5.2 8.2 7.8 3.2 4.3 5.6 5.4 2.9 4.9 8.2 3.8 3.7 5.5 4.5 9.0 5.3 5.2 5.4 23.3 5.7 6.1 5.0 4.7 5.0 4.4 4.3 5.9 4.2 7.3 16.9 4.6 4.0 3.6 7.2 4.6 5.4 7.5 7.1 13.4 12.2 1.8 9.1 7.2 10.3 6.7 2.4 7.7 4.8 5.7 12.9 4.5 4.6 9.4 12.4 11.0 10.4 4.8 7.6 3.0 7.6 11.4 6.7 7.7 13.3 14.2 12.1 17.4 9.5 10.2 10.4 9.7 3.1 10.9 8.0 3.8 4.4 0.9 10.2 10.2 4.2 4.7 2.7 11.9 2.5 5.4 2.8 11.8 9.7 10.4 3.8 3.5 7.2 10.2 4.1 3.3 8.7 4.2 4.5 4.3 4.5 7.1 13.8 8.6 7.5 3.7 3.2 1.6 2.6 0.8 4.9 1.6 1.9 3.3 2.3 1.4 1.8 9.1 2.5 3.9 3.2 1.5 1.8 5.4 6.0 4.8 7.7 5.1 5.2 5.6 5.4 5.5 4.7 5.9 7.2 5.6 3.2 4.4 10.1 3.7 2.3 5.6 14.3 2.2 7.7 6.1 5.1 14.4 4.3 7.3 7.3 6.2 10.1 3.7 18.8 23.5 9.1 7.8 5.5 8.1 7.9 3.0 2.1 13.0 6.9 4.7 5.7 4.1 6.1 4.5 9.2 7.5 9.0 12.9 10.1 14.3 7.6 12.2 10.3 2.7 3.7 6.5 7.2 5.4 4.7 13.5 9.6 12.3 6.0 13.2 6.0 6.2 6.4 0.9 5.9 19.0 14.3 8.6 7.1 6.6 5.9 5.1 17.3 8.3 3.6 1.8 9.0 3.6 13.1 14.5 4.8 NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 44957992-45109016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 344.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" NA NA 94000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane" "HPA022949: AB_1854534, HPA022963: AB_1854535" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (1.30e-2)" "unprognostic (6.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (4.96e-3)" "unprognostic (3.86e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (3.77e-3)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (4.17e-3)" "unprognostic (9.45e-2)" 28.3 31.8 36.2 22.3 37.7 19.5 25.8 30.3 43.4 24.7 27.9 27.8 23.6 26.4 15.7 28.8 27.7 20.3 28.3 38.8 36.4 27.3 39.5 26.5 33.6 35.4 33.7 26.3 22.2 37.8 23.3 36.6 35.0 24.5 29.2 25.7 32.1 27.6 44.6 23.9 26.4 32.9 33.9 28.4 24.5 24.9 37.2 35.2 30.7 47.6 39.5 33.0 23.5 34.9 51.5 88.8 53.7 42.3 82.9 75.0 60.6 41.4 87.6 115.9 101.0 83.9 57.0 54.0 86.2 80.4 78.4 51.5 94.5 92.3 132.9 117.9 73.3 49.0 60.7 84.4 53.7 71.0 62.6 66.4 64.1 79.1 69.2 64.1 87.1 60.9 81.8 38.1 63.1 49.2 76.2 31.7 42.4 151.5 87.8 57.5 67.2 52.2 73.6 78.8 39.2 32.9 33.0 30.2 38.0 112.8 73.1 46.0 50.1 69.9 49.5 55.8 68.1 41.4 61.0 69.9 64.5 44.5 56.4 34.9 49.4 20.0 23.8 33.3 19.9 42.3 19.9 20.1 26.2 31.0 23.7 18.8 26.5 21.1 27.6 115.5 25.7 11.8 36.2 37.7 30.3 43.4 38.8 36.4 35.4 33.7 35.0 33.9 37.2 34.9 50.1 38.5 29.5 49.3 53.8 13.9 15.4 48.8 24.5 97.8 74.1 57.1 46.5 97.2 33.6 69.9 116.7 73.7 87.5 48.7 78.2 69.4 31.1 51.5 63.1 46.4 50.9 72.0 30.3 71.2 61.9 39.6 21.9 62.3 22.8 28.1 85.3 344.4 47.6 129.5 30.7 43.0 28.5 86.5 15.9 12.2 55.0 34.6 10.6 18.7 97.9 41.5 59.8 20.1 19.3 67.9 52.0 51.1 31.0 15.3 84.1 108.1 24.0 123.5 59.2 16.1 46.3 67.6 35.5 20.5 14.1 81.8 40.1 25.4 68.6 18.6 NOL3 "ARC, CARD2, MYP, NOP30" ENSG00000140939 "Nucleolar protein 3" O60936 16 67170154-67175735 "Disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009208 Enhanced Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "CAB009208: AB_634091" "unprognostic (2.83e-2)" "unprognostic (1.63e-2)" "unprognostic (3.34e-3)" "unprognostic (1.07e-1)" "unprognostic (2.70e-3)" "unprognostic (2.83e-1)" "prognostic unfavorable (6.43e-5)" "unprognostic (5.74e-2)" "unprognostic (4.07e-2)" "unprognostic (1.83e-1)" "unprognostic (2.15e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.39e-2)" "unprognostic (3.65e-2)" "unprognostic (3.90e-2)" "unprognostic (1.48e-2)" 34.4 77.5 36.1 3.8 37.1 0.7 35.4 36.7 36.2 37.1 30.7 32.5 6.7 27.8 11.4 48.6 35.4 10.2 99.3 32.9 35.0 33.0 52.0 28.9 3.1 43.9 36.2 29.3 50.6 37.7 60.2 11.6 39.6 70.1 7.6 28.6 51.1 13.8 142.2 79.2 18.1 8.0 35.4 15.9 28.2 7.6 36.9 2.8 35.6 97.5 4.1 38.7 39.8 38.1 14.9 23.9 3.9 22.1 19.2 14.5 22.0 11.8 12.5 12.6 7.4 5.2 38.2 0.3 38.0 13.8 3.3 24.3 5.4 18.3 3.0 13.4 8.3 0.6 19.8 7.8 12.0 1.3 2.9 8.9 33.1 9.9 7.0 35.9 5.3 5.2 5.5 15.3 24.0 38.7 0.3 1.9 3.7 13.5 58.1 13.3 8.3 29.8 21.5 4.5 31.1 16.6 49.5 35.3 5.7 5.1 75.5 4.0 12.4 16.5 14.1 16.3 10.3 22.1 7.5 4.2 46.4 3.7 5.7 0.0 3.5 0.0 0.1 0.3 0.0 0.0 1.7 0.1 1.1 0.0 0.0 0.2 0.8 0.4 0.1 1.1 0.0 1.3 36.1 37.1 36.7 36.2 32.9 35.0 43.9 36.2 39.6 35.4 36.9 38.1 5.1 28.9 33.6 19.2 2.7 13.8 27.6 70.6 21.6 18.5 29.3 32.6 51.2 35.8 28.8 3.7 16.7 8.1 0.8 18.2 15.6 61.3 1.2 8.6 14.0 10.1 22.3 0.0 5.0 34.7 11.3 13.8 11.2 16.4 2.5 7.6 13.2 30.9 11.4 55.5 7.6 23.7 38.7 4.1 4.5 0.7 25.1 3.4 21.4 4.7 14.6 36.3 1.0 4.0 11.3 44.2 11.4 30.1 10.4 28.5 15.5 26.2 21.3 47.9 13.1 38.7 32.3 0.3 1.2 16.4 19.7 11.1 3.2 3.6 16.4 31.6 NPRL2 "NPR2, NPR2L, TUSC4" ENSG00000114388 "NPR2 like, GATOR1 complex subunit" Q8WTW4 3 50347330-50350826 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038196, HPA038197" Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "HPA038196: AB_10675631, HPA038197: AB_10671523" "unprognostic (7.25e-3)" "unprognostic (2.01e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-1)" "unprognostic (6.44e-2)" "unprognostic (2.11e-2)" "unprognostic (3.06e-3)" "prognostic favorable (1.59e-4)" "unprognostic (7.86e-2)" "unprognostic (1.22e-2)" "unprognostic (1.60e-3)" "unprognostic (5.69e-2)" "unprognostic (4.28e-2)" "unprognostic (4.55e-2)" "unprognostic (3.14e-1)" "unprognostic (4.49e-1)" "unprognostic (3.06e-2)" 4.9 9.2 9.4 5.0 9.7 5.1 7.4 10.0 11.0 9.0 9.4 8.3 5.3 5.3 11.1 6.8 8.8 6.2 10.3 10.0 11.1 9.3 12.9 5.1 8.0 9.7 10.7 7.8 16.4 12.1 9.0 5.7 10.1 7.7 8.5 5.7 12.1 8.1 14.7 7.5 5.6 6.9 10.0 6.8 7.2 7.8 9.9 9.6 8.3 18.0 9.2 5.8 5.3 10.3 12.2 11.9 7.9 14.5 22.5 11.8 8.2 6.4 16.5 17.1 16.8 9.3 11.0 13.9 9.5 11.9 8.6 6.7 18.1 18.5 12.3 10.0 12.9 16.6 10.0 18.2 20.2 20.7 21.9 14.3 19.3 21.8 15.0 11.5 16.8 20.2 9.5 13.6 14.7 2.4 19.3 14.8 8.7 37.2 33.4 7.1 5.0 34.5 19.7 12.1 6.0 14.1 7.3 11.1 12.5 8.2 17.5 10.4 6.0 7.2 9.2 13.8 11.7 16.8 22.0 11.8 14.6 25.5 7.3 40.6 17.4 46.7 72.7 18.1 63.4 23.2 36.4 62.7 20.6 21.1 30.8 48.5 22.9 64.1 20.8 16.6 49.8 50.7 9.4 9.7 10.0 11.0 10.0 11.1 9.7 10.7 10.1 10.0 9.9 10.3 13.4 9.6 11.9 7.8 19.0 12.0 9.8 26.7 14.8 18.4 18.2 19.9 13.2 15.7 16.3 14.7 20.9 27.4 31.4 15.8 37.2 15.9 94.6 8.1 9.4 11.3 11.9 30.3 7.2 15.0 21.5 12.9 18.3 7.1 19.0 12.6 11.7 14.8 14.7 25.2 7.9 20.9 38.7 13.2 10.3 66.6 19.3 7.4 12.4 2.8 15.0 15.0 68.0 5.0 6.5 12.2 12.8 15.1 19.4 7.7 30.7 30.0 15.6 26.4 6.6 11.1 22.1 16.8 14.9 15.4 12.5 9.0 29.3 16.0 18.8 7.7 NQO2 "DHQV, DIA6, NMOR2, QR2" ENSG00000124588 "N-ribosyldihydronicotinamide:quinone reductase 2" P16083 6 2987987-3019755 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 202.5;Proximal tubular cells: 730.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 240.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021283, HPA021332" Enhanced Supported Nucleoplasm,Cytosol NA NA 6000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA021283: AB_1854600, HPA021332: AB_1854601" "unprognostic (7.11e-3)" "unprognostic (1.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-2)" "unprognostic (3.58e-1)" "prognostic unfavorable (8.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (4.90e-2)" "unprognostic (6.59e-2)" "unprognostic (3.60e-2)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-2)" "unprognostic (3.96e-1)" "unprognostic (2.02e-1)" 60.0 121.5 48.1 27.0 48.8 72.1 45.0 61.1 65.4 32.6 64.3 28.2 35.3 25.8 32.9 32.8 30.0 31.5 76.5 48.5 49.6 190.3 124.2 30.4 19.5 61.8 47.9 29.8 42.6 33.5 21.2 28.6 61.4 28.1 19.6 31.1 61.9 28.9 123.6 50.7 35.6 19.8 42.9 39.3 36.1 18.2 51.5 18.3 26.8 144.9 18.2 31.8 29.0 53.2 45.7 75.7 42.1 95.3 73.0 42.9 45.4 40.5 51.2 37.1 40.9 80.0 16.1 36.9 144.7 71.1 86.4 33.7 45.4 28.5 28.9 95.9 37.1 23.6 83.0 77.3 59.7 24.4 73.9 27.8 34.2 44.9 40.9 53.4 36.8 47.9 142.3 24.1 30.8 95.5 27.0 44.4 54.9 87.6 59.8 49.3 50.1 108.2 56.6 24.0 11.4 15.9 59.5 25.9 128.9 75.0 35.4 16.9 60.7 34.8 14.4 45.9 18.1 45.4 116.7 12.3 43.3 69.5 72.7 25.2 91.8 52.8 33.1 64.2 24.4 12.1 29.6 29.8 61.7 9.1 17.8 19.6 240.2 30.0 60.8 6.5 37.2 43.2 48.1 48.8 61.1 65.4 48.5 49.6 61.8 47.9 61.4 42.9 51.5 53.2 30.3 9.6 16.1 9.8 16.3 35.2 41.5 32.7 12.5 34.8 34.2 32.1 72.8 47.1 21.3 25.8 10.4 42.6 18.2 21.2 162.4 29.1 51.6 15.1 21.4 28.0 4.8 43.8 47.0 63.4 53.9 51.5 33.1 9.0 13.9 11.0 25.7 202.5 76.6 42.1 46.7 23.3 30.5 44.7 105.7 62.8 35.8 75.4 67.6 19.7 148.6 54.0 20.6 10.6 9.1 55.8 18.3 41.0 15.0 38.6 103.7 730.3 28.7 22.5 26.3 35.0 42.9 24.8 11.4 35.4 41.2 31.2 20.8 21.9 25.4 41.8 NTAQ1 "C8orf32, FLJ10204, WDYHV1" ENSG00000156795 "N-terminal glutamine amidase 1" Q96HA8 8 123416726-123470028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Cardiomyocytes: 21.9;Cytotrophoblasts: 13.9;Extravillous trophoblasts: 23.0;Hofbauer cells: 13.2;Syncytiotrophoblasts: 10.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA024823: AB_1845773, HPA053680: AB_2682228" "unprognostic (9.97e-2)" "unprognostic (4.82e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.69e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "unprognostic (5.39e-2)" "unprognostic (7.46e-2)" "unprognostic (2.37e-1)" 7.1 10.9 16.2 5.1 16.7 5.9 13.5 16.3 24.0 12.8 15.5 7.5 4.3 8.1 8.9 6.9 7.5 6.7 20.1 14.8 17.8 13.0 6.8 6.8 7.4 17.0 17.9 18.2 9.6 11.0 10.5 6.8 17.4 10.2 7.9 14.9 6.9 8.8 16.0 7.7 4.4 9.5 15.8 5.2 8.5 12.7 20.0 7.1 12.8 17.6 10.1 8.8 7.2 17.7 26.6 26.9 39.2 18.1 15.3 40.9 14.5 19.1 21.3 23.4 26.1 15.8 17.8 19.7 19.8 23.8 32.7 12.8 25.8 29.7 31.4 53.1 15.8 25.6 13.2 22.4 21.2 12.7 10.9 24.1 16.0 29.3 32.8 27.1 22.6 41.2 18.8 29.0 33.5 84.3 30.2 14.4 12.3 65.6 20.5 13.5 20.0 20.4 31.1 22.6 18.6 34.1 20.7 109.0 35.8 44.5 17.6 12.2 9.8 26.5 46.2 19.7 26.4 17.4 38.1 24.1 18.8 14.1 19.1 16.3 5.7 2.1 6.2 8.7 7.4 5.0 7.3 7.7 9.0 4.1 6.2 6.9 1.5 16.0 3.8 5.2 10.6 4.6 16.2 16.7 16.3 24.0 14.8 17.8 17.0 17.9 17.4 15.8 20.0 17.7 5.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 13.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 23.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.0 0.3 0.0 0.0 0.0 NTMT1 "AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NRMT1" ENSG00000148335 "N-terminal Xaa-Pro-Lys N-methyltransferase 1" Q9BV86 9 129608884-129636135 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 391.4;Late spermatids: 761.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020092, HPA058420" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA020092: AB_1853831, HPA058420: AB_2683713" "unprognostic (4.74e-3)" "unprognostic (1.77e-1)" "unprognostic (2.44e-1)" "unprognostic (1.48e-1)" "unprognostic (1.17e-1)" "unprognostic (1.24e-3)" "unprognostic (4.17e-3)" "unprognostic (4.92e-2)" "unprognostic (1.24e-1)" "unprognostic (8.57e-2)" "unprognostic (3.63e-1)" "unprognostic (4.35e-2)" "unprognostic (1.00e-3)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "unprognostic (5.58e-2)" "unprognostic (3.50e-3)" 26.4 68.6 20.6 19.3 21.7 24.5 22.1 23.6 27.0 22.5 22.4 23.2 18.3 19.6 15.9 20.2 18.9 19.9 67.9 21.0 23.1 31.5 41.6 22.8 20.2 22.5 23.8 19.8 31.1 22.4 23.4 19.6 22.5 22.7 11.2 6.3 22.4 16.7 98.9 25.1 19.5 13.7 21.3 29.7 24.9 93.3 22.9 16.1 17.9 84.3 16.0 23.9 20.0 24.1 57.8 117.2 47.9 82.2 30.0 44.6 50.2 107.6 63.5 108.1 92.8 96.6 74.0 74.8 53.7 78.5 76.7 110.1 101.8 96.4 66.8 56.3 50.9 31.2 106.3 100.4 96.3 63.3 45.0 47.0 48.6 113.5 56.0 34.2 60.1 64.1 116.5 54.2 57.5 194.1 72.0 85.6 62.6 105.4 96.6 66.8 55.8 150.4 43.7 32.4 96.5 48.5 53.1 97.3 74.7 30.2 81.4 32.4 41.8 129.1 64.5 118.7 115.3 41.2 53.7 115.2 59.0 64.4 75.0 32.9 49.7 39.2 43.7 55.1 43.7 43.2 43.5 46.5 49.2 50.4 43.9 36.3 13.6 30.6 70.9 52.8 44.5 36.4 20.6 21.7 23.6 27.0 21.0 23.1 22.5 23.8 22.5 21.3 22.9 24.1 35.6 3.2 13.9 5.9 45.9 99.8 85.7 50.3 16.5 18.3 33.4 33.8 4.1 20.0 35.7 22.0 22.9 72.6 23.1 49.7 97.8 60.5 391.4 21.4 29.8 38.3 20.3 23.4 6.4 55.9 86.8 41.1 21.9 23.2 30.4 20.5 20.0 52.7 67.0 42.1 6.5 44.0 42.7 27.6 80.3 761.6 35.1 34.3 55.2 3.7 33.1 23.3 25.7 4.5 9.2 69.2 29.9 24.8 41.0 105.7 84.5 89.6 22.5 23.6 26.3 34.1 58.8 129.2 43.2 19.2 99.3 135.6 38.3 39.2 48.4 70.7 NUDCD3 "KIAA1068, NudCL" ENSG00000015676 "NudC domain containing 3" Q8IVD9 7 44379119-44490658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019136, HPA019528, HPA019529" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA019136: AB_1852370, HPA019528: AB_1852372, HPA019529: AB_1852374" "unprognostic (3.72e-2)" "unprognostic (9.28e-3)" "unprognostic (2.33e-2)" "unprognostic (2.05e-3)" "unprognostic (2.18e-3)" "unprognostic (2.05e-2)" "unprognostic (4.73e-2)" "unprognostic (2.30e-2)" "unprognostic (2.18e-1)" "unprognostic (3.96e-2)" "unprognostic (2.28e-1)" "unprognostic (5.62e-2)" "prognostic favorable (9.16e-4)" "unprognostic (3.51e-2)" "unprognostic (1.58e-2)" "unprognostic (1.45e-1)" "unprognostic (6.50e-2)" 2.9 2.8 6.8 1.3 9.0 2.8 2.8 3.2 7.2 2.5 0.0 2.4 1.2 2.2 2.4 2.7 3.5 2.2 7.5 6.6 5.1 2.2 1.8 2.4 2.2 4.4 5.5 3.1 3.3 3.7 1.8 1.7 5.6 2.8 1.8 4.8 2.4 3.3 8.2 3.1 2.0 3.0 3.9 1.9 2.7 3.9 5.6 2.1 2.7 5.7 2.2 2.3 1.8 6.3 2.6 4.9 3.4 6.3 4.2 3.4 1.3 4.1 4.0 4.8 4.9 3.3 1.8 8.1 3.0 5.5 6.6 3.0 4.8 5.6 2.8 4.8 4.9 2.2 2.9 2.3 3.8 3.9 1.3 3.1 3.7 3.6 4.1 2.8 5.9 2.4 6.1 2.6 3.6 2.3 1.6 3.7 4.3 2.5 6.3 2.3 3.7 3.0 2.7 4.0 3.6 10.6 2.4 4.5 1.8 3.4 3.4 5.7 5.7 3.3 3.4 2.2 3.3 7.3 8.1 4.0 3.6 4.5 5.9 0.6 0.8 0.9 1.0 0.8 1.1 1.0 0.9 0.9 0.7 1.0 0.9 0.9 0.5 0.8 1.0 0.6 1.0 0.9 6.8 9.0 3.2 7.2 6.6 5.1 4.4 5.5 5.6 3.9 5.6 6.3 30.5 12.8 19.2 35.9 26.4 11.3 13.0 16.5 20.5 40.9 29.3 25.3 44.5 17.2 16.0 38.6 54.2 19.6 21.9 22.7 23.5 29.6 87.7 27.4 34.4 25.3 17.4 22.3 59.6 21.6 18.1 23.9 23.9 30.9 9.5 35.8 22.5 32.8 18.3 48.8 58.8 25.1 26.4 17.9 9.5 98.3 30.4 13.9 16.0 46.9 21.2 24.8 34.0 36.2 61.2 27.4 18.8 28.2 14.3 15.9 27.2 26.8 21.9 40.2 32.9 17.8 25.2 106.6 21.1 25.5 16.2 14.4 26.2 18.9 27.8 13.3 NUDT6 "FGF-AS, FGF2AS, gfg, gfg-1" ENSG00000170917 "Nudix hydrolase 6" P53370 4 122888697-122922968 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 37.2;Early spermatids: 36.7;Proximal tubular cells: 46.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039202, HPA066115" Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039202: AB_10795032, HPA066115: AB_2685620" "unprognostic (7.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (3.11e-1)" "unprognostic (3.84e-2)" "unprognostic (4.23e-2)" "unprognostic (2.36e-1)" "unprognostic (3.79e-1)" "unprognostic (1.07e-1)" "unprognostic (6.29e-2)" "unprognostic (6.91e-6)" "unprognostic (1.13e-5)" "unprognostic (2.32e-1)" "unprognostic (7.60e-2)" "unprognostic (7.98e-2)" "unprognostic (2.16e-1)" 4.9 10.7 8.2 2.8 9.4 2.2 5.3 5.8 10.6 4.2 6.6 7.7 4.4 4.1 7.1 3.3 6.7 3.6 13.0 8.4 8.2 19.4 27.3 3.2 3.9 6.0 7.3 4.2 4.0 7.4 6.4 3.2 6.1 3.7 6.2 8.3 5.2 4.3 10.0 4.2 3.7 3.5 5.9 4.5 3.3 7.1 9.0 4.8 7.3 10.9 2.3 3.2 3.2 7.8 5.4 7.9 11.5 10.3 10.3 10.7 4.1 6.1 8.1 5.3 7.3 3.4 12.1 5.6 4.5 3.3 11.7 2.7 5.1 4.8 5.4 13.5 3.4 5.0 7.6 9.2 3.8 10.4 3.0 6.6 2.1 4.6 4.0 9.8 7.0 9.7 12.8 13.8 9.0 6.3 14.5 11.2 4.3 20.8 9.9 4.9 14.6 6.4 12.7 3.2 6.1 7.6 6.3 8.5 12.5 13.3 5.6 8.3 4.4 12.8 6.7 11.2 5.6 15.4 12.9 10.7 7.7 15.4 5.8 0.0 2.0 0.0 1.5 2.8 1.9 4.0 2.0 2.6 4.4 1.2 1.5 1.7 0.3 1.3 2.5 1.7 2.3 1.8 8.2 9.4 5.8 10.6 8.4 8.2 6.0 7.3 6.1 5.9 9.0 7.8 7.0 16.0 7.8 10.7 2.0 0.9 3.1 9.3 4.6 12.5 4.7 6.9 5.3 4.3 5.4 5.5 0.0 16.4 1.3 4.1 37.2 6.2 36.7 8.9 7.4 5.4 7.2 3.0 8.9 5.6 3.7 5.3 5.6 3.4 1.3 12.8 4.6 21.3 8.7 15.2 9.6 6.0 6.1 4.6 2.0 6.1 6.2 5.0 5.4 4.7 1.5 14.0 0.0 13.6 10.8 4.7 5.2 9.1 3.8 1.2 2.5 46.2 10.4 11.9 0.0 6.3 5.0 28.5 3.7 3.9 1.8 4.0 3.3 20.8 10.1 2.1 OCIAD1 "Asrij, FLJ20455, OCIA, TPA018" ENSG00000109180 "OCIA domain containing 1" Q9NX40 4 48805212-48861817 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044803 Approved Approved Mitochondria NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA044803: AB_10961287" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" "unprognostic (4.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.60e-1)" "unprognostic (4.10e-1)" "unprognostic (2.83e-3)" "unprognostic (1.34e-1)" "unprognostic (5.42e-2)" "unprognostic (1.47e-3)" "unprognostic (9.23e-2)" "unprognostic (2.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-2)" 129.5 184.0 161.1 99.4 170.6 107.7 153.9 154.6 212.9 150.3 173.5 161.1 155.8 138.0 192.2 118.1 167.2 124.6 219.3 177.3 177.0 238.1 326.5 124.1 127.3 161.1 153.1 159.1 156.1 248.7 109.9 118.4 157.6 145.9 159.9 143.7 161.9 148.1 255.0 107.1 134.6 133.3 163.1 105.1 141.3 91.0 165.8 133.6 239.4 255.9 133.9 136.3 72.3 172.6 165.2 118.2 231.7 162.8 230.8 283.0 178.6 253.1 393.8 261.1 311.3 110.6 473.2 190.4 241.5 238.0 311.4 141.7 229.4 250.4 296.2 149.4 152.7 293.4 105.7 88.1 336.5 309.1 300.9 292.0 353.5 208.3 258.4 315.4 270.0 173.9 339.8 104.1 300.0 107.7 261.4 287.6 195.2 211.7 110.4 169.6 216.9 203.1 502.9 154.5 139.8 261.0 120.4 101.1 306.5 179.8 212.8 271.5 196.9 176.1 200.7 120.7 333.1 256.3 380.4 283.1 223.2 251.0 220.2 47.8 60.2 76.5 62.6 68.0 90.8 74.1 73.1 79.2 75.4 64.9 90.2 80.5 48.3 95.4 86.5 85.2 68.5 73.5 161.1 170.6 154.6 212.9 177.3 177.0 161.1 153.1 157.6 163.1 165.8 172.6 176.7 160.3 124.5 85.8 107.1 79.7 111.3 243.3 102.4 126.6 96.7 119.6 152.3 102.9 169.4 121.4 66.7 170.5 103.1 140.0 137.0 140.0 34.3 147.3 120.5 120.2 130.1 89.8 125.1 128.3 168.8 124.4 84.1 110.5 141.8 102.6 118.9 167.3 152.7 89.2 137.2 131.3 124.1 94.0 77.2 35.5 132.3 106.1 87.2 76.8 107.2 206.1 121.5 106.1 158.1 130.7 122.5 139.2 115.3 104.2 164.1 178.9 151.2 111.6 124.9 121.3 112.7 188.3 88.3 94.1 75.9 164.7 109.8 197.2 142.7 100.4 OMA1 "FLJ33782, MPRP-1, YKR087C, ZMPOMA1" ENSG00000162600 "OMA1 zinc metallopeptidase" Q96E52 1 58415384-58546802 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055120 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "HPA055120: AB_2682702" "prognostic favorable (1.63e-4)" "unprognostic (2.67e-2)" "prognostic favorable (7.70e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-1)" "unprognostic (9.57e-2)" "unprognostic (3.94e-3)" "prognostic favorable (8.52e-4)" "unprognostic (8.22e-3)" "unprognostic (6.91e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (9.54e-3)" "unprognostic (2.52e-2)" "unprognostic (3.93e-2)" "unprognostic (1.74e-2)" "unprognostic (5.24e-3)" 11.4 18.7 15.1 14.0 22.8 12.8 19.7 23.1 14.9 16.7 14.9 20.8 14.9 13.5 17.8 13.3 19.4 15.1 19.8 13.0 19.5 28.4 31.1 11.9 23.4 18.8 17.9 13.5 17.9 18.1 10.4 11.5 21.1 20.8 20.0 20.5 19.5 16.7 28.2 12.8 14.2 12.4 15.6 20.2 17.3 8.2 18.3 20.2 20.1 29.9 21.5 14.8 10.5 27.3 31.2 13.0 8.3 7.9 41.7 39.0 24.6 12.7 13.9 10.9 13.7 4.0 18.7 69.8 26.3 13.1 37.8 31.2 31.1 31.3 13.3 55.1 17.9 22.0 10.4 16.1 20.3 54.3 14.7 37.3 33.6 10.4 22.4 24.1 9.3 34.3 42.7 20.1 29.2 19.5 18.0 19.4 12.4 47.4 28.5 22.1 27.7 29.1 23.6 20.5 8.7 4.3 26.0 41.9 37.6 38.4 19.5 20.1 5.4 5.6 10.8 27.8 13.5 16.3 23.4 46.2 16.8 42.2 14.1 20.1 14.4 32.1 19.4 24.1 25.6 35.6 23.7 23.1 15.4 35.0 33.9 31.5 17.2 30.9 35.1 8.2 23.6 15.9 15.1 22.8 23.1 14.9 13.0 19.5 18.8 17.9 21.1 15.6 18.3 27.3 8.4 19.2 11.5 37.9 25.7 6.0 18.2 35.6 13.6 7.8 15.0 12.3 27.2 8.6 33.0 25.8 12.5 22.9 14.4 8.4 25.4 11.2 5.8 31.6 10.8 6.3 6.0 15.6 18.3 5.5 10.0 12.0 5.6 18.4 6.3 10.9 6.4 18.7 15.8 1.7 31.7 17.7 36.7 10.1 9.7 12.7 9.9 12.9 7.2 29.0 11.3 10.9 15.5 52.8 106.5 3.8 10.9 8.6 16.8 12.3 8.5 32.4 63.1 20.5 6.6 12.0 8.6 14.3 13.6 17.3 6.8 18.3 20.7 17.1 14.6 17.1 OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1 mitochondrial dynamin like GTPase" O60313 3 193593144-193697811 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria NA NA 10000 "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Mitochondria" "HPA036926: AB_10671247, HPA036927: AB_2675388" "unprognostic (2.10e-2)" "unprognostic (9.23e-3)" "unprognostic (7.98e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (1.62e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (3.48e-2)" "prognostic favorable (1.84e-4)" "unprognostic (2.92e-1)" "unprognostic (4.75e-1)" "unprognostic (4.50e-3)" "unprognostic (3.21e-1)" 15.0 12.0 14.3 7.6 17.4 25.6 12.8 15.2 19.5 10.4 9.4 18.9 16.8 10.9 9.1 14.6 8.1 10.2 39.3 18.6 17.4 18.3 20.9 8.5 11.8 16.4 15.4 8.4 10.1 23.1 3.8 11.7 16.8 12.3 16.6 9.6 11.7 13.3 24.2 11.9 13.8 13.5 12.4 9.3 14.6 6.3 15.2 12.7 13.9 44.5 12.4 13.0 5.1 13.7 58.9 18.8 18.2 20.2 15.8 25.0 19.3 27.5 26.2 30.0 29.0 45.2 19.3 38.6 58.1 27.0 27.3 37.3 32.7 31.7 53.5 46.5 25.7 67.9 16.7 23.1 24.9 55.8 29.8 28.4 27.6 30.0 40.9 18.5 26.2 15.7 28.4 37.0 30.2 46.5 21.9 30.9 25.8 33.9 59.9 27.8 40.1 41.6 22.7 36.1 39.8 24.2 41.8 46.3 29.5 14.1 60.3 43.5 26.3 27.7 20.8 29.3 58.7 33.1 41.3 74.0 30.5 43.7 28.4 9.7 7.3 7.1 5.8 8.2 5.5 6.8 5.5 5.6 7.8 5.1 5.6 6.0 2.7 4.7 17.3 4.0 6.6 5.2 14.3 17.4 15.2 19.5 18.6 17.4 16.4 15.4 16.8 12.4 15.2 13.7 24.8 16.0 24.0 72.1 27.5 15.9 16.4 17.4 24.5 19.5 20.9 13.5 135.2 22.8 20.1 18.4 31.3 19.0 24.6 31.4 17.6 19.3 7.7 20.3 25.2 23.8 23.4 86.3 106.8 24.0 14.9 24.6 31.1 26.1 19.6 25.6 14.3 39.1 17.9 21.9 106.7 20.6 10.2 25.6 14.7 13.5 15.8 28.1 21.4 58.1 22.9 14.6 11.3 87.4 98.1 28.9 12.1 14.7 29.3 18.7 24.6 34.1 19.6 23.4 6.6 21.3 26.2 15.1 16.6 34.3 22.4 17.9 22.3 28.2 26.7 22.1 PAFAH1B1 "LIS1, MDCR, MDS, NudF, PAFAH" ENSG00000007168 "Platelet activating factor acetylhydrolase 1b regulatory subunit 1" P43034 17 2593210-2685615 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Lipid degradation, Lipid metabolism, Mitosis, Neurogenesis, Transport" "Developmental protein" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 640.0;Late spermatids: 1864.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004489, HPA020036" Approved Supported Centrosome NA NA 860000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "CAB004489: AB_627889, HPA020036: AB_1854925" "unprognostic (1.54e-3)" "unprognostic (6.84e-2)" "unprognostic (2.10e-1)" "unprognostic (2.51e-1)" "unprognostic (2.13e-1)" "unprognostic (3.19e-3)" "unprognostic (3.17e-2)" "unprognostic (6.36e-2)" "unprognostic (2.27e-1)" "unprognostic (6.62e-2)" "unprognostic (3.89e-3)" "unprognostic (5.80e-2)" "prognostic favorable (3.16e-4)" "unprognostic (3.31e-1)" "unprognostic (3.51e-1)" "unprognostic (7.45e-2)" "unprognostic (5.58e-2)" 34.8 32.2 35.5 27.2 43.1 4.0 32.6 31.5 46.5 38.3 6.7 46.4 30.5 43.9 26.9 38.0 36.7 31.8 51.1 46.2 47.4 41.4 30.0 37.3 30.9 41.3 38.4 35.4 26.3 56.4 38.4 32.4 48.1 32.6 32.8 47.2 32.4 38.6 87.7 42.1 36.5 44.4 30.2 31.0 34.6 55.7 36.7 41.5 43.9 73.2 38.8 35.7 37.8 38.0 51.3 53.3 81.8 28.4 66.9 74.1 27.3 76.5 67.1 56.3 53.0 69.7 18.7 64.5 63.5 100.3 27.4 53.5 74.4 59.8 80.6 50.9 48.4 56.4 48.8 27.3 69.3 37.5 66.4 68.8 73.5 58.8 58.1 71.7 58.1 51.8 38.8 32.7 84.8 21.1 58.3 28.6 36.7 30.5 27.0 39.5 67.6 30.0 62.5 30.5 37.4 62.0 63.0 34.5 65.5 51.8 36.5 30.1 84.9 71.5 17.1 57.1 61.0 24.7 32.1 28.8 60.4 33.7 66.2 2.6 1.7 3.4 4.7 2.5 5.2 2.9 4.1 3.3 2.5 2.4 4.9 3.8 2.6 3.6 3.8 1.5 5.1 2.4 35.5 43.1 31.5 46.5 46.2 47.4 41.3 38.4 48.1 30.2 36.7 38.0 73.7 121.8 92.2 90.8 82.7 118.7 114.8 74.3 63.2 102.4 52.1 42.9 136.3 30.0 101.6 35.0 50.1 56.4 117.2 77.4 35.2 77.2 640.0 82.2 95.5 77.2 34.1 45.9 178.1 56.3 76.7 74.7 87.7 100.9 93.7 45.1 43.2 32.3 60.2 102.6 161.8 43.7 57.0 46.3 77.0 1864.4 64.0 77.6 56.9 104.9 90.3 60.7 97.9 115.1 193.5 100.8 61.5 56.8 91.7 91.6 76.9 55.0 80.7 65.8 46.0 84.5 133.0 256.8 78.1 69.7 132.6 129.6 92.7 54.7 39.2 122.4 PARK7 "DJ-1, DJ1, GATD2" ENSG00000116288 "Parkinsonism associated deglycase" Q99497 1 7954291-7985505 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Fertilization, Inflammatory response, Stress response" "Chaperone, Hydrolase, Protease, RNA-binding" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004190, CAB005870" Supported Supported Nucleoplasm,Cytosol NA NA 35000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "CAB005870: AB_444361, HPA004190: AB_1079566" "unprognostic (6.88e-3)" "unprognostic (7.50e-2)" "unprognostic (3.48e-2)" "unprognostic (1.16e-2)" "unprognostic (4.08e-2)" "unprognostic (5.68e-2)" "unprognostic (7.45e-2)" "unprognostic (9.63e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-3)" "unprognostic (8.17e-2)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (7.43e-2)" 249.4 373.6 283.5 213.7 290.0 205.0 235.7 292.9 403.4 201.1 327.7 252.5 145.8 212.2 278.0 161.0 203.2 162.9 388.0 285.5 296.6 311.0 397.6 181.6 269.2 289.6 286.0 234.2 308.5 387.6 283.6 174.1 291.7 234.9 194.9 273.8 240.9 185.6 771.4 127.1 170.5 199.1 295.2 188.2 234.2 139.6 288.1 217.9 286.3 541.8 249.7 226.5 171.2 299.7 537.0 452.5 467.1 523.2 459.8 442.6 218.4 476.7 434.4 450.4 360.3 419.9 549.4 633.1 534.2 505.1 328.6 367.1 483.2 625.3 579.3 574.5 526.2 683.0 678.6 674.5 403.8 662.9 418.6 421.3 262.4 459.8 547.4 359.2 478.2 340.1 676.8 471.7 633.0 485.0 474.3 868.7 376.1 653.6 465.4 366.7 598.0 888.7 714.7 269.7 527.7 447.4 470.4 728.0 798.4 370.1 414.9 503.7 459.3 412.8 344.6 395.5 539.5 452.8 788.4 938.8 551.5 1002.9 606.4 298.4 590.2 394.0 484.7 553.7 459.2 483.6 478.2 577.3 717.4 374.6 406.8 466.8 202.5 551.1 456.9 1378.2 874.4 1060.8 283.5 290.0 292.9 403.4 285.5 296.6 289.6 286.0 291.7 295.2 288.1 299.7 243.6 131.4 157.1 23.2 211.8 208.9 402.4 677.7 200.9 196.2 342.0 381.8 453.3 257.4 318.5 248.3 79.2 553.0 382.3 131.1 851.0 504.3 32.1 272.1 263.9 241.7 238.0 177.1 19.5 478.4 612.1 302.3 146.3 195.9 206.5 291.2 183.1 368.1 435.1 186.7 22.9 279.6 484.2 204.5 304.5 53.6 358.2 258.9 359.3 21.5 605.4 816.4 327.5 18.1 36.0 378.9 186.9 378.7 269.7 523.4 227.1 941.5 327.8 235.5 276.1 277.8 342.6 288.2 302.2 220.4 143.8 469.6 244.4 535.3 312.2 433.1 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019545 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favorable (9.11e-5)" 38.4 35.8 46.5 26.6 48.2 33.8 40.3 47.4 66.2 33.8 50.7 47.7 29.2 31.9 57.7 36.7 30.2 19.7 54.1 46.6 48.2 39.6 45.0 28.4 32.0 47.7 48.7 31.7 49.9 39.7 32.0 25.5 47.4 37.1 41.9 32.7 40.5 30.3 54.9 37.1 34.7 29.7 47.2 36.2 42.6 26.7 47.6 34.5 31.4 51.6 33.8 38.9 31.5 48.4 115.1 55.6 39.7 33.0 38.8 42.1 80.2 39.2 59.4 80.5 65.0 172.0 59.0 47.8 90.0 56.7 73.5 49.2 64.1 68.0 90.0 71.6 76.1 73.9 35.5 96.9 57.3 73.9 61.6 60.0 85.4 58.0 70.7 38.5 59.0 82.4 42.6 45.0 69.2 131.0 148.3 194.3 105.5 100.6 53.3 64.7 72.8 92.0 79.0 97.6 37.9 52.0 47.6 162.9 107.8 48.1 159.2 143.5 31.8 29.3 63.0 60.9 108.2 89.2 65.7 116.0 56.6 75.1 35.5 97.5 143.1 133.4 51.3 107.8 60.9 62.4 57.3 59.9 132.4 59.1 68.7 54.2 41.3 67.1 83.3 79.7 73.7 116.1 46.5 48.2 47.4 66.2 46.6 48.2 47.7 48.7 47.4 47.2 47.6 48.4 30.3 22.4 19.7 17.9 37.6 30.3 54.9 93.5 26.7 35.9 31.8 31.5 41.2 35.8 44.5 31.3 31.3 58.9 38.4 24.4 117.4 63.9 24.0 15.2 18.3 30.2 33.7 23.3 23.4 84.7 49.0 35.1 28.1 13.7 69.8 33.1 33.2 30.4 77.7 33.7 24.1 42.0 77.3 56.2 55.7 9.7 28.9 57.5 42.7 33.7 79.3 55.9 50.4 17.1 28.0 60.3 35.1 27.1 42.3 55.4 47.3 86.0 30.5 51.1 6.6 44.8 96.6 47.8 47.4 40.2 30.0 42.1 40.9 49.0 49.2 58.8 PCGF5 "MGC16202, RNF159" ENSG00000180628 "Polycomb group ring finger 5" Q86SE9 10 91163012-91284337 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 345.7;Oligodendrocytes: 252.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038349, HPA059071" Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA038349: AB_10669523, HPA059071: " "unprognostic (1.34e-2)" "unprognostic (8.22e-2)" "unprognostic (1.25e-2)" "unprognostic (7.41e-2)" "unprognostic (1.15e-1)" "unprognostic (8.35e-2)" "unprognostic (6.53e-2)" "unprognostic (6.43e-2)" "unprognostic (3.89e-1)" "unprognostic (3.24e-2)" "unprognostic (3.75e-2)" "unprognostic (1.49e-1)" "prognostic favorable (4.98e-4)" "unprognostic (2.43e-1)" "unprognostic (2.00e-1)" "unprognostic (2.56e-2)" "prognostic favorable (6.90e-4)" 13.7 21.8 17.8 13.1 18.9 5.8 11.9 17.4 20.0 12.0 10.9 15.3 17.6 12.5 10.7 12.8 12.1 12.7 28.3 14.2 25.2 23.4 26.2 13.1 16.9 21.8 21.2 14.9 16.2 19.9 7.2 15.9 17.7 13.7 14.1 16.3 17.6 14.0 15.2 11.2 21.0 11.9 17.6 17.8 14.7 11.4 21.1 19.4 24.2 16.7 15.7 12.2 8.5 23.0 32.9 14.2 11.6 5.0 16.5 25.7 8.3 18.2 37.3 16.2 22.5 2.2 18.7 43.2 8.3 22.9 13.3 6.3 12.6 12.5 28.4 50.1 9.5 20.4 9.0 22.2 21.8 16.0 31.0 11.7 22.6 12.1 16.8 33.2 13.7 19.0 11.1 23.5 25.4 6.1 36.2 4.1 1.7 7.5 8.1 17.8 21.5 11.7 29.6 5.1 5.5 7.8 8.9 9.4 15.6 4.1 7.6 7.1 35.9 19.0 13.4 11.8 21.8 40.8 26.9 38.2 26.7 11.4 6.0 6.4 1.6 2.7 2.6 4.0 4.7 4.0 3.9 2.7 2.1 3.9 3.9 3.9 2.1 5.1 7.7 0.5 2.4 2.6 17.8 18.9 17.4 20.0 14.2 25.2 21.8 21.2 17.7 17.6 21.1 23.0 35.8 6.4 24.0 135.8 60.1 34.4 48.7 34.8 38.7 20.2 26.8 30.6 81.2 28.6 28.3 29.5 16.7 16.5 49.7 82.8 49.0 33.9 127.8 25.2 38.7 33.8 21.6 124.8 99.0 63.9 5.0 32.7 33.1 29.0 23.4 14.0 35.3 58.6 50.5 50.5 159.5 65.4 20.3 73.1 64.9 345.7 19.6 65.9 42.7 56.2 74.0 79.9 40.2 107.1 252.6 54.3 55.1 29.7 72.3 61.2 83.7 59.0 27.9 19.3 13.1 59.1 39.4 78.2 14.4 34.4 31.3 5.6 55.9 10.9 49.0 67.2 PDCD5 "MGC9294, TFAR19" ENSG00000105185 "Programmed cell death 5" O14737 19 32581190-32587453 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018471 Enhanced Approved Nucleoplasm,Cytosol NA NA 47000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "HPA018471: AB_1855108" "unprognostic (1.04e-1)" "unprognostic (2.08e-1)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (2.02e-1)" "unprognostic (8.64e-2)" "unprognostic (3.64e-3)" "unprognostic (2.43e-2)" "unprognostic (6.22e-2)" "unprognostic (8.49e-2)" "unprognostic (3.87e-2)" "unprognostic (1.93e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.00e-2)" "unprognostic (3.35e-2)" "unprognostic (1.10e-1)" "unprognostic (9.54e-2)" 95.7 96.1 86.2 73.8 87.0 46.8 82.0 85.4 110.2 73.2 80.8 100.1 65.8 68.8 50.8 109.3 70.9 34.8 170.9 86.7 91.1 97.8 101.2 68.0 58.6 87.1 87.7 71.8 102.4 52.6 95.1 61.2 88.4 64.3 55.7 39.2 70.1 41.9 224.2 60.5 62.0 65.8 85.8 56.8 78.9 144.4 94.6 41.8 60.6 132.2 59.5 91.1 80.3 89.9 499.0 630.0 168.8 163.7 223.8 334.0 190.0 353.2 225.6 295.2 252.2 525.0 188.3 272.6 498.7 177.1 286.3 133.2 213.6 281.7 254.4 493.1 333.6 412.4 303.9 382.8 284.0 587.0 157.3 219.7 253.8 195.9 315.0 145.1 198.8 214.9 381.0 298.8 247.2 332.0 243.6 298.6 164.9 410.5 211.6 238.9 248.8 323.6 231.9 167.6 326.0 178.4 338.1 351.8 283.4 125.2 152.6 294.6 299.4 272.6 291.7 274.2 602.7 270.6 413.0 504.4 302.3 459.8 244.2 40.7 93.4 50.9 106.4 149.0 134.3 147.3 167.4 132.1 120.6 116.3 115.3 114.3 13.7 116.9 197.6 123.6 217.8 122.7 86.2 87.0 85.4 110.2 86.7 91.1 87.1 87.7 88.4 85.8 94.6 89.9 115.4 73.7 62.7 16.6 70.4 121.6 174.0 292.0 97.3 43.2 129.1 216.4 336.1 94.4 119.4 75.4 27.1 194.7 69.0 94.6 189.8 245.3 469.7 94.0 166.4 121.3 71.3 44.8 24.0 247.3 216.5 150.4 64.2 115.0 46.9 84.9 83.6 151.1 146.7 50.5 29.3 113.6 140.4 48.3 93.1 481.2 142.6 67.4 124.5 11.2 113.8 104.0 66.9 17.6 16.8 292.2 100.4 123.0 124.4 392.4 125.1 216.8 107.9 45.3 72.3 126.8 218.4 487.0 413.1 170.9 119.9 143.0 78.4 164.9 157.8 140.4 PET117 CSRP2BP ENSG00000232838 "PET117 cytochrome c oxidase chaperone" Q6UWS5 20 18137863-18143169 "Disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA047716 Approved "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA047716: AB_2680128" "unprognostic (1.34e-2)" "unprognostic (2.83e-1)" "unprognostic (3.94e-1)" "unprognostic (2.02e-1)" "unprognostic (2.39e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (4.76e-6)" "unprognostic (7.74e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-2)" "unprognostic (4.90e-1)" "unprognostic (2.78e-1)" "prognostic favorable (4.15e-4)" "unprognostic (3.73e-1)" "unprognostic (4.63e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" 8.7 16.8 12.5 5.5 13.0 8.0 8.5 12.8 17.8 8.4 13.5 12.2 15.6 9.9 10.4 8.0 8.5 5.1 12.9 12.6 12.9 14.1 12.5 8.0 6.0 12.7 12.4 10.0 11.4 9.7 11.8 7.4 13.0 9.3 9.4 9.7 10.4 6.5 22.9 10.8 10.9 5.8 12.8 8.6 16.5 7.2 12.8 4.5 8.9 9.6 5.3 9.5 7.6 13.8 33.0 28.7 10.4 10.6 14.9 11.3 29.8 16.8 16.5 19.6 18.2 26.5 26.7 19.5 27.0 16.1 34.9 17.6 19.0 31.5 20.5 4.4 20.9 21.9 19.2 63.8 24.6 29.2 23.2 17.8 17.1 19.3 20.1 15.7 15.7 23.3 18.6 17.1 14.3 26.8 17.1 33.5 15.4 35.2 31.8 15.3 33.4 35.0 21.2 19.4 18.9 18.6 23.1 43.0 46.9 27.1 26.2 21.3 15.0 17.7 13.7 19.0 29.4 24.4 41.8 31.5 8.8 9.5 16.3 3.4 24.9 11.4 18.3 23.3 20.7 26.2 22.7 23.0 22.0 23.2 31.6 24.2 1.5 21.0 29.7 41.0 20.4 15.8 12.5 13.0 12.8 17.8 12.6 12.9 12.7 12.4 13.0 12.8 12.8 13.8 10.3 19.2 10.6 0.3 11.4 3.8 16.7 17.2 8.0 16.9 13.5 14.6 13.7 35.8 16.3 16.5 4.2 29.8 12.4 15.4 33.2 21.8 1.0 12.3 8.8 9.1 15.7 16.8 2.6 26.7 34.5 10.1 24.5 11.9 8.8 6.9 8.9 25.8 14.9 23.5 2.5 18.4 16.2 13.9 4.0 3.2 16.1 7.7 7.2 1.9 15.1 19.7 16.5 3.5 1.4 34.0 12.3 6.8 9.4 26.8 44.0 53.1 9.4 13.7 6.6 9.6 10.8 16.3 31.3 13.4 6.3 13.0 11.9 9.7 23.6 14.5 PEX11B ENSG00000131779 "Peroxisomal biogenesis factor 11 beta" O96011 1 145911350-145918717 "Disease related genes, Predicted membrane proteins" "Peroxisome biogenesis" "Peroxisome biogenesis disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017150, HPA050104" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA017150: , HPA050104: AB_2681017" "unprognostic (4.59e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.29e-1)" "unprognostic (3.62e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.67e-4)" "prognostic favorable (6.85e-4)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (2.10e-1)" "unprognostic (8.48e-2)" "unprognostic (6.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (7.62e-3)" "unprognostic (4.28e-1)" 17.5 25.1 34.7 19.0 35.8 13.3 31.2 32.5 42.5 24.6 33.3 24.9 24.6 23.4 33.1 34.3 25.7 17.0 28.0 36.3 38.1 32.4 27.1 20.1 27.4 33.3 33.0 24.6 27.2 33.5 24.5 23.1 35.1 24.3 27.6 20.2 28.7 25.6 39.8 28.1 25.9 21.0 31.6 27.7 28.3 30.8 34.1 30.2 26.4 34.9 34.7 23.2 22.2 34.2 27.1 24.4 21.0 21.1 48.6 37.9 21.9 26.8 35.3 34.4 26.5 11.3 30.7 25.2 28.1 38.3 16.6 31.9 18.6 40.0 24.0 28.4 14.1 15.6 14.8 29.2 68.3 46.9 27.5 49.9 49.3 23.3 22.8 43.9 44.5 34.8 28.7 40.5 54.7 43.1 35.8 43.5 7.5 57.4 29.5 33.0 31.5 55.5 58.8 19.1 14.7 24.0 20.2 38.4 24.7 20.5 53.2 72.0 39.7 23.1 18.2 30.3 19.8 43.1 54.0 35.1 38.5 26.3 16.0 89.6 64.7 47.3 58.5 60.9 64.8 93.2 67.5 65.4 70.8 84.1 74.7 67.9 32.4 71.1 60.5 94.9 79.6 82.7 34.7 35.8 32.5 42.5 36.3 38.1 33.3 33.0 35.1 31.6 34.1 34.2 5.0 16.0 10.3 9.8 17.0 19.4 9.2 41.3 26.7 8.0 16.8 17.0 12.8 17.2 20.7 40.5 0.0 37.9 19.6 20.2 45.0 13.7 12.2 8.2 7.0 12.3 12.7 14.1 13.0 13.8 13.9 11.1 19.4 7.4 3.8 9.3 18.2 32.9 23.0 5.0 13.5 16.0 20.3 18.3 10.7 21.1 14.0 12.9 21.4 4.7 27.1 12.6 25.7 9.5 12.9 16.0 11.4 19.9 17.4 10.1 20.1 34.5 22.9 5.1 6.6 5.8 10.3 41.1 24.3 34.0 22.0 20.0 13.8 11.6 15.8 9.4 PEX12 ENSG00000108733 "Peroxisomal biogenesis factor 12" O00623 17 35574795-35578863 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 17.2;Spermatocytes: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069386 Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA069386: AB_2686135" "unprognostic (1.45e-1)" "unprognostic (6.06e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-1)" "unprognostic (1.72e-1)" "unprognostic (1.17e-1)" "unprognostic (1.98e-1)" "unprognostic (9.04e-2)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (5.55e-2)" "unprognostic (2.64e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" 3.9 6.8 6.7 3.6 7.2 1.5 5.5 7.9 9.1 5.3 6.7 3.4 3.6 4.3 10.7 3.4 5.6 3.2 9.1 6.8 7.1 8.2 9.0 3.4 4.8 6.8 6.9 8.2 4.0 7.8 4.7 4.7 6.8 5.7 2.9 4.6 5.5 6.9 10.3 4.2 3.5 3.5 7.3 3.9 3.9 6.8 7.0 3.2 7.7 10.8 4.5 3.7 2.7 8.4 2.8 3.7 5.4 4.4 11.0 9.9 3.9 7.3 8.3 6.0 6.3 3.2 3.0 6.4 11.6 4.1 4.9 7.3 6.6 4.8 5.2 2.3 8.7 4.7 3.8 5.9 12.8 6.7 1.2 9.2 9.2 3.7 10.9 7.7 4.6 5.2 7.5 6.6 7.2 2.9 7.9 3.8 2.2 6.3 5.8 3.8 9.3 6.4 7.1 4.2 4.0 4.0 4.6 3.0 9.6 6.5 7.4 3.7 3.7 5.6 3.5 6.3 4.9 13.3 9.9 7.5 6.0 5.1 5.2 2.2 1.5 3.0 1.8 1.1 3.2 2.3 3.0 1.8 1.7 2.6 4.1 3.5 1.0 2.0 1.2 1.7 2.4 1.4 6.7 7.2 7.9 9.1 6.8 7.1 6.8 6.9 6.8 7.3 7.0 8.4 2.7 3.2 0.5 6.5 3.3 0.6 1.9 1.3 1.8 2.1 2.4 2.2 6.3 0.0 2.7 3.7 0.0 6.7 1.4 1.3 3.9 3.5 17.2 1.9 2.3 3.9 1.2 0.8 1.3 1.1 4.1 2.6 2.6 1.5 2.5 2.0 3.3 5.4 2.9 1.7 1.9 1.7 2.0 2.6 0.6 3.0 3.1 1.5 1.8 1.0 0.9 8.3 1.0 4.5 2.8 2.2 1.0 1.5 0.5 2.4 2.7 3.3 1.8 2.2 0.0 2.6 3.7 21.0 10.2 1.4 1.3 5.2 2.8 3.0 2.2 1.3 PEX5 "PTS1R, PXR1" ENSG00000139197 "Peroxisomal biogenesis factor 5" P50542 12 7188685-7218574 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Rhizomelic chondrodysplasia punctata, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Early spermatids: 277.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 156.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039259, HPA039260" Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Cytosol" "HPA039259: AB_10673419, HPA039260: AB_2676417" "unprognostic (7.44e-2)" "unprognostic (2.54e-2)" "unprognostic (1.41e-1)" "unprognostic (1.86e-1)" "unprognostic (1.27e-1)" "unprognostic (4.46e-1)" "unprognostic (1.48e-1)" "unprognostic (2.20e-2)" "unprognostic (5.14e-2)" "unprognostic (3.72e-2)" "unprognostic (1.63e-2)" "unprognostic (2.92e-1)" "unprognostic (5.70e-2)" "unprognostic (7.31e-3)" "unprognostic (1.96e-1)" "unprognostic (2.13e-2)" "unprognostic (1.13e-1)" 33.1 27.8 43.7 13.2 42.8 8.8 34.2 38.0 43.3 25.0 33.5 25.3 12.1 26.0 10.9 18.8 23.2 13.6 22.0 39.1 38.5 24.5 37.8 22.1 18.6 40.9 41.2 29.2 30.4 18.9 44.1 10.0 41.2 19.7 11.8 13.6 22.2 13.6 74.1 26.2 20.3 15.2 43.1 16.0 22.2 50.9 45.4 39.3 20.0 28.4 20.8 21.7 21.2 40.9 14.7 24.7 13.0 34.2 29.1 19.9 24.3 14.0 16.6 16.2 17.2 36.9 21.8 156.1 8.3 16.2 23.6 18.2 22.1 19.5 16.8 20.8 18.2 13.8 19.0 25.7 15.4 21.3 13.6 22.2 35.2 11.1 34.5 22.0 14.2 75.0 28.2 5.3 14.7 20.0 49.7 18.5 38.6 28.0 13.1 23.7 28.1 21.4 13.0 21.4 10.9 22.6 20.9 45.4 20.1 26.2 10.2 12.5 12.7 18.2 29.9 15.8 17.2 9.5 11.6 53.4 18.0 22.8 12.2 0.0 1.6 2.1 2.9 1.4 3.6 1.9 2.0 2.9 2.6 1.4 2.6 2.6 1.2 2.8 4.1 4.6 0.9 2.2 43.7 42.8 38.0 43.3 39.1 38.5 40.9 41.2 41.2 43.1 45.4 40.9 8.6 12.8 20.1 11.4 5.6 14.5 7.2 5.2 8.0 7.8 9.2 8.5 13.7 14.3 5.6 7.3 8.4 11.3 5.1 9.9 9.8 10.1 277.8 7.0 13.6 10.3 7.2 4.6 31.5 14.9 6.4 7.8 4.1 5.2 3.8 7.2 5.7 17.6 4.7 13.5 22.1 7.2 4.1 5.4 5.0 43.7 14.3 5.2 5.4 1.0 4.6 12.7 5.2 16.1 13.3 10.2 14.2 13.9 2.9 14.1 9.9 19.3 9.8 7.0 19.7 12.0 10.2 32.2 16.6 7.4 15.3 7.7 5.8 9.6 10.4 5.7 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 953.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 590000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 71.5 109.2 196.7 54.5 200.5 64.6 62.4 206.2 245.6 76.0 192.2 74.0 54.0 44.7 103.0 70.6 99.3 62.0 267.2 192.3 203.3 82.6 47.9 57.3 57.4 199.3 191.9 65.0 153.4 160.9 85.2 49.8 200.3 89.2 50.5 26.3 144.0 86.6 432.6 45.8 62.9 78.1 198.8 41.6 61.5 56.9 199.1 68.5 86.7 441.5 40.0 71.8 41.4 216.2 53.6 452.5 225.6 199.1 153.4 266.0 412.8 147.6 170.8 158.8 138.6 165.7 138.0 145.1 142.8 168.6 180.0 155.0 51.2 293.9 50.2 116.9 132.5 45.4 276.8 380.3 177.5 82.6 176.4 322.8 248.7 91.8 109.5 145.8 218.8 93.1 102.9 129.7 257.2 328.2 156.9 176.7 216.0 372.5 206.6 106.5 106.6 196.7 255.6 113.3 137.6 132.8 146.7 155.8 75.1 107.0 127.2 226.4 177.0 390.6 130.8 91.5 166.5 60.5 93.4 94.0 174.3 59.7 235.8 38.2 290.0 31.0 197.6 318.4 170.7 241.3 173.9 184.6 321.8 178.9 126.0 175.8 13.7 196.7 231.7 425.4 223.6 324.1 196.7 200.5 206.2 245.6 192.3 203.3 199.3 191.9 200.3 198.8 199.1 216.2 125.7 96.1 159.8 24.8 111.8 150.3 187.7 659.2 204.9 43.9 223.1 317.7 384.8 178.7 326.5 217.0 22.9 322.1 111.8 337.1 747.4 196.1 271.3 122.2 168.1 111.9 265.1 80.2 8.1 252.4 489.5 213.1 140.6 170.3 123.5 367.4 83.6 201.9 286.5 67.3 12.5 370.9 309.3 97.2 197.1 953.5 205.0 133.6 334.4 5.6 273.2 194.7 146.2 10.6 25.0 185.3 359.8 223.4 187.8 257.5 540.1 817.4 250.6 77.7 85.5 137.1 249.6 141.8 143.8 140.3 161.8 264.1 106.4 352.5 336.0 199.5 PIGX FLJ20522 ENSG00000163964 "Phosphatidylinositol glycan anchor biosynthesis class X" Q8TBF5 3 196639775-196736007 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 87.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 87.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029409, HPA073301" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029409: AB_10610280, HPA073301: " "unprognostic (8.83e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.14e-1)" "unprognostic (2.42e-3)" "unprognostic (9.25e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.45e-5)" "unprognostic (1.91e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-2)" "unprognostic (3.18e-2)" "unprognostic (4.02e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "unprognostic (1.53e-1)" "unprognostic (1.46e-1)" "unprognostic (2.01e-1)" 10.5 10.3 14.4 10.4 15.6 9.0 9.9 14.7 16.7 7.5 19.5 10.8 9.1 8.3 12.4 10.3 7.9 8.3 9.6 15.2 16.7 12.2 8.2 7.2 7.1 15.1 15.8 6.8 9.0 19.6 12.7 8.3 14.8 12.8 10.1 17.4 9.9 10.5 17.1 10.4 9.1 11.2 16.0 6.8 7.6 6.0 16.2 11.6 9.2 14.1 10.9 8.7 7.6 16.7 39.4 18.7 21.4 18.1 22.7 15.3 12.6 18.1 20.7 19.3 20.5 13.7 25.6 20.3 63.6 15.4 25.1 22.2 19.5 16.6 23.1 18.6 19.6 21.0 12.8 12.6 19.2 20.6 34.6 15.1 25.7 17.1 15.7 16.3 12.7 36.5 11.7 38.6 21.0 30.1 59.2 32.1 12.8 30.7 18.3 31.1 27.6 29.5 24.6 11.5 24.4 29.2 31.8 23.9 29.7 16.9 71.8 20.3 8.2 18.1 9.2 25.6 29.5 57.0 70.4 41.1 20.7 26.9 21.5 39.6 7.5 87.5 3.3 10.8 3.0 4.6 3.1 4.6 7.7 5.5 3.7 3.2 18.8 8.7 11.6 3.3 4.4 4.1 14.4 15.6 14.7 16.7 15.2 16.7 15.1 15.8 14.8 16.0 16.2 16.7 14.2 19.2 16.3 13.7 16.4 17.1 30.1 5.5 31.9 34.9 28.3 19.2 12.6 21.5 8.4 29.5 47.9 21.4 31.6 20.8 35.2 7.9 30.5 17.2 23.5 16.9 15.7 15.8 17.7 5.6 20.9 22.0 9.2 17.9 12.0 19.3 17.5 16.6 20.1 33.7 23.7 17.0 8.2 21.4 25.4 22.7 28.0 18.1 21.4 15.9 25.0 50.0 32.0 12.1 14.5 5.2 12.5 35.0 20.1 33.8 27.1 32.5 10.2 39.1 26.3 23.6 28.1 27.1 36.0 29.3 15.9 11.6 21.2 22.7 25.7 23.0 PIGY MGC14156 ENSG00000255072 "Phosphatidylinositol glycan anchor biosynthesis class Y" Q3MUY2 4 88520998-88523776 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059018 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "HPA059018: AB_2683884" 35.7 39.6 35.1 23.1 37.0 44.5 48.2 38.7 43.4 32.1 33.8 30.7 30.7 34.0 45.6 28.4 33.8 22.5 32.3 34.0 37.3 41.2 52.0 26.3 27.8 36.7 35.6 34.3 41.3 41.9 3.3 28.5 36.5 32.3 31.2 22.9 43.1 33.9 48.6 27.1 28.3 36.2 39.2 26.1 24.6 22.4 36.2 27.3 32.0 42.3 29.4 28.7 3.7 39.3 60.1 19.8 39.1 46.4 76.7 78.3 26.2 43.2 60.6 53.1 44.6 15.5 46.3 0.2 47.3 61.7 36.4 25.2 35.6 54.4 66.6 73.4 61.8 66.2 24.8 59.9 58.0 110.7 40.9 54.4 80.8 34.5 69.5 50.4 88.5 20.4 75.9 64.9 77.8 45.5 68.5 67.6 32.7 70.5 37.5 68.0 36.3 69.8 44.4 33.4 46.7 45.7 54.9 49.4 119.9 38.4 23.0 54.8 60.6 56.1 51.9 55.3 40.6 45.6 40.1 7.5 49.3 55.7 63.1 82.4 92.1 79.0 90.4 94.9 102.2 98.9 103.2 98.3 111.0 80.5 105.4 101.6 18.1 108.9 95.3 68.3 116.8 186.1 35.1 37.0 38.7 43.4 34.0 37.3 36.7 35.6 36.5 39.2 36.2 39.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PKD1L1 PRO19563 ENSG00000158683 "Polycystin 1 like 1, transient receptor potential channel interacting" Q8TDX9 7 47740202-47948466 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adipocytes: 9.1;Astrocytes: 13.4;Early spermatids: 11.8;Excitatory neurons: 25.7;Inhibitory neurons: 37.9;Microglial cells: 15.0;Oligodendrocyte precursor cells: 11.6;Oligodendrocytes: 17.1" "Cancer enhanced" "Detected in single" "testis cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "T-47d: 5.9;U-266/70: 14.7;U-266/84: 5.7" "Not detected" "Not detected" "HPA020422, HPA022424" Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA020422: AB_1855434, HPA022424: AB_1855435" "unprognostic (5.47e-2)" "unprognostic (5.33e-3)" "unprognostic (1.49e-2)" "unprognostic (9.74e-2)" "unprognostic (4.03e-2)" "unprognostic (6.31e-2)" "unprognostic (2.52e-2)" "unprognostic (1.11e-1)" "unprognostic (9.63e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (1.88e-4)" "unprognostic (1.88e-3)" "unprognostic (2.56e-1)" "unprognostic (2.50e-1)" "unprognostic (1.90e-1)" 1.7 0.1 1.1 0.4 0.9 1.1 0.5 2.1 1.9 0.2 0.0 0.4 0.9 0.3 0.6 0.4 0.3 0.4 2.6 0.4 1.3 0.3 0.8 0.4 0.9 0.5 0.7 0.3 0.3 0.1 0.4 0.6 0.7 0.3 0.5 1.7 0.4 0.1 2.8 0.5 0.4 0.4 0.1 0.3 0.4 1.5 0.8 1.5 0.4 3.3 0.6 0.6 0.1 1.1 0.4 0.7 0.6 0.8 0.1 0.0 1.2 0.3 0.2 0.2 0.4 0.8 0.4 0.3 0.3 0.4 0.4 0.8 0.5 0.6 0.6 0.2 0.4 0.3 0.3 0.8 0.0 0.5 0.3 0.2 0.1 0.3 0.2 0.2 1.1 0.4 0.4 1.1 0.5 0.2 0.3 0.3 0.4 0.0 0.2 0.2 0.3 0.3 0.1 0.7 0.5 0.4 0.5 0.3 0.4 0.5 5.9 0.1 0.1 0.5 1.1 0.2 0.3 14.7 5.7 0.5 0.2 0.2 0.3 0.9 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.1 1.1 0.9 2.1 1.9 0.4 1.3 0.5 0.7 0.7 0.1 0.8 1.1 9.1 0.0 0.0 13.4 0.3 0.1 0.0 0.0 0.0 3.1 0.1 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.8 0.5 0.1 3.7 0.0 0.0 25.7 0.2 0.2 1.7 0.0 0.3 0.0 0.2 2.2 0.1 1.4 1.7 37.9 0.7 0.0 0.3 0.0 5.3 0.3 0.2 0.0 15.0 0.0 0.5 0.0 11.6 17.1 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 1.5 0.0 0.4 0.2 1.4 0.6 0.0 0.0 0.0 0.1 0.3 0.8 0.0 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cytokinetic bridge" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 59.2 45.1 47.1 40.4 50.3 66.8 49.0 44.6 52.4 46.6 44.2 72.4 14.5 61.0 13.6 16.2 48.7 23.9 89.0 40.9 46.3 43.1 25.0 71.1 49.4 53.6 48.4 38.7 52.5 32.8 44.9 33.3 49.8 43.8 9.3 11.5 41.3 30.6 81.7 20.1 45.2 33.0 49.8 90.4 51.4 50.2 49.2 35.6 39.6 53.8 25.8 60.3 32.8 48.5 152.8 88.9 32.3 67.8 51.3 59.8 53.0 53.5 63.5 55.2 52.5 34.9 84.2 144.4 135.0 92.2 68.9 34.4 52.1 23.8 21.2 117.6 67.7 172.8 55.4 75.2 169.1 68.2 103.9 43.3 17.0 33.5 52.2 62.5 129.8 74.9 78.0 96.7 41.4 62.5 104.1 63.2 59.2 54.7 100.0 138.5 43.9 104.7 27.3 24.2 117.3 166.0 33.2 41.7 88.9 15.5 37.8 117.7 196.6 108.8 46.1 133.2 82.8 126.5 123.6 78.9 71.5 135.7 87.4 27.6 27.9 40.6 30.4 38.5 23.3 15.9 20.5 21.1 26.8 16.9 18.6 21.0 32.6 22.1 52.3 17.0 25.7 29.0 47.1 50.3 44.6 52.4 40.9 46.3 53.6 48.4 49.8 49.8 49.2 48.5 78.1 3.2 2.2 17.3 35.3 3.7 6.4 1.9 1.8 37.2 17.6 14.7 4.0 27.1 3.1 35.0 16.7 2.8 77.9 4.9 1.9 28.2 4.9 27.0 25.4 49.4 40.2 17.7 3.6 30.1 14.5 20.8 30.1 20.7 2.5 80.9 53.2 11.3 59.8 48.8 8.6 10.9 8.2 69.0 17.0 8.4 19.9 56.2 17.8 17.8 48.2 61.2 102.0 7.5 11.9 64.2 10.6 23.0 27.1 12.7 1.1 15.2 12.4 29.2 26.3 21.7 29.2 9.3 42.2 1.3 2.7 3.7 55.5 34.3 4.8 4.9 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924740-154936719 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 266.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved NA NA 15000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favorable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 39.9 56.4 99.0 29.8 100.1 15.3 35.0 97.9 108.9 33.4 95.0 39.9 45.9 25.9 17.7 77.7 37.2 17.2 63.1 93.9 96.4 53.8 91.9 30.1 34.6 98.6 97.4 35.8 41.6 58.2 60.3 23.7 96.0 32.4 22.2 19.8 34.0 27.1 79.1 69.2 44.2 27.7 96.4 45.7 40.5 26.6 102.3 27.9 31.5 47.4 36.8 31.9 37.9 99.8 51.8 72.9 46.7 72.5 43.6 30.9 48.5 40.5 29.3 38.9 37.0 30.6 101.0 75.1 75.9 49.3 40.5 49.4 65.3 63.9 17.8 103.3 28.9 34.1 104.1 29.0 40.0 51.4 29.3 36.3 58.7 70.2 49.6 19.5 40.0 65.9 36.8 221.7 41.3 108.3 40.8 51.0 41.0 121.7 95.0 60.3 29.8 171.1 66.1 38.4 37.7 91.1 44.1 75.7 51.9 35.0 146.7 91.1 32.7 35.8 29.2 84.4 62.1 174.0 153.2 131.8 58.9 83.9 46.7 28.0 80.9 91.8 68.2 205.6 110.1 114.8 93.1 70.6 93.6 111.1 59.1 59.1 6.9 59.7 219.4 96.5 134.3 80.0 99.0 100.1 97.9 108.9 93.9 96.4 98.6 97.4 96.0 96.4 102.3 99.8 22.7 57.7 37.5 9.4 42.2 69.8 105.9 95.8 51.8 38.5 67.1 68.3 57.3 78.6 42.2 53.3 8.4 235.7 31.5 65.0 266.1 69.6 9.0 45.0 28.5 29.8 66.4 35.6 5.1 71.3 108.1 45.1 46.9 44.2 22.2 49.8 39.3 146.9 141.0 37.0 7.0 78.9 67.1 67.9 49.5 13.5 42.6 47.8 65.8 3.7 49.5 119.1 41.2 8.0 11.8 61.7 61.7 47.8 58.8 53.7 219.3 246.1 22.1 27.4 32.9 46.0 48.4 51.3 51.3 81.0 90.5 227.7 45.1 162.6 79.9 76.2 POLR2C RPB3 ENSG00000102978 "RNA polymerase II subunit C" P19387 16 57462660-57472009 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040919, HPA041826" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA040919: AB_10795483, HPA041826: AB_10793935" "unprognostic (2.10e-2)" "unprognostic (4.42e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.90e-1)" "unprognostic (9.54e-2)" "unprognostic (1.95e-1)" "unprognostic (2.48e-2)" "unprognostic (2.60e-2)" "unprognostic (6.63e-2)" "prognostic favorable (3.03e-6)" "unprognostic (2.29e-1)" "unprognostic (2.31e-2)" "unprognostic (1.20e-1)" "unprognostic (5.43e-3)" 35.1 41.6 49.9 30.4 51.2 43.9 39.6 52.3 60.3 36.8 49.4 36.0 33.1 39.2 67.1 31.2 47.0 31.3 52.1 51.0 52.0 59.8 62.3 47.7 38.7 50.5 51.0 54.3 45.1 55.1 46.9 39.5 51.8 40.4 40.0 59.3 39.0 45.9 74.2 34.5 31.8 40.6 52.4 30.8 36.4 25.4 50.4 47.7 40.8 61.4 44.9 39.1 31.2 54.5 59.3 94.0 81.2 72.7 72.7 62.9 67.6 75.4 84.9 126.0 82.3 121.7 74.7 65.8 86.4 89.3 75.6 60.5 111.9 83.5 134.2 30.2 77.0 51.1 53.5 142.0 81.8 95.0 94.4 57.8 66.4 96.7 88.7 66.6 74.8 90.0 90.2 37.3 81.6 78.6 106.9 98.6 118.4 72.1 138.0 151.4 94.4 120.5 99.7 56.7 102.5 117.4 122.9 69.8 81.4 74.0 51.6 85.2 54.4 76.3 76.3 56.8 89.0 82.2 76.2 135.0 75.3 79.5 102.5 79.8 38.3 70.3 44.6 37.8 49.2 52.4 50.6 42.8 38.1 48.4 60.4 57.4 96.9 64.6 49.5 31.2 54.9 60.5 49.9 51.2 52.3 60.3 51.0 52.0 50.5 51.0 51.8 52.4 50.4 54.5 49.5 25.6 43.0 11.1 49.2 31.0 46.0 51.3 30.1 81.6 39.4 52.5 11.0 41.5 31.9 27.6 56.3 78.8 49.8 38.2 92.0 62.9 5.6 25.0 25.4 39.0 38.2 35.6 13.3 65.8 80.8 40.5 15.8 22.3 61.0 46.1 23.2 25.1 41.2 52.2 13.9 34.5 48.8 22.9 30.3 8.4 51.6 22.7 40.9 8.4 49.1 102.7 58.7 8.0 9.6 59.5 44.6 51.9 40.0 43.9 63.8 120.4 29.4 93.9 46.0 30.0 49.1 50.4 66.4 30.0 30.0 92.9 52.9 49.0 38.4 43.5 POLR2F "HRBP14.4, RPB6" ENSG00000100142 "RNA polymerase II, I and III subunit F" P61218 22 37952607-38041915 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "melanoma: 1.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000827, CAB009882" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "CAB009882: AB_2299942, HPA000827: AB_1079834" "unprognostic (8.27e-2)" "unprognostic (7.50e-2)" "unprognostic (1.51e-3)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (2.73e-3)" "unprognostic (2.85e-1)" "unprognostic (5.87e-2)" "unprognostic (4.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.11e-4)" "unprognostic (9.08e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-1)" "unprognostic (7.86e-2)" 52.5 61.1 73.4 34.6 92.3 38.9 50.8 77.5 90.2 59.5 56.9 64.9 37.7 53.2 24.8 58.7 50.2 19.5 91.8 74.2 91.2 58.2 118.6 41.6 31.0 87.9 83.9 60.9 47.5 76.5 62.7 30.2 82.6 47.7 28.7 16.8 56.1 39.6 111.0 45.8 42.3 28.8 75.3 36.4 57.6 48.8 86.8 36.7 54.7 68.4 26.3 53.1 52.7 123.7 150.7 176.2 120.6 128.7 141.1 81.7 109.4 138.0 81.0 141.4 130.5 210.0 51.8 117.4 99.1 120.3 138.3 106.4 166.9 135.7 67.1 143.0 303.7 107.3 181.3 289.1 125.9 213.6 67.0 112.4 99.8 186.3 72.1 71.2 118.7 130.4 208.9 93.7 101.9 220.2 168.4 258.2 174.3 175.4 134.7 162.3 110.4 134.5 77.4 94.8 180.6 67.2 129.5 88.9 215.3 69.6 62.9 144.3 110.5 119.8 173.9 150.4 158.1 106.0 178.0 247.9 122.4 107.9 138.4 118.9 92.9 140.8 83.8 90.4 78.5 95.8 71.9 81.8 86.3 71.3 63.1 63.7 122.8 113.7 78.5 123.3 103.4 85.3 73.4 92.3 77.5 90.2 74.2 91.2 87.9 83.9 82.6 75.3 86.8 123.7 82.6 38.5 85.9 9.4 73.2 204.3 113.9 205.4 63.7 26.7 133.8 168.7 0.3 101.5 122.5 121.4 25.0 243.5 70.5 148.7 193.7 160.0 117.0 96.0 117.2 94.8 117.2 109.6 9.9 159.5 303.4 97.4 58.1 82.4 90.0 90.0 98.6 304.4 178.5 28.6 10.7 143.1 116.0 94.2 102.9 42.0 159.7 65.9 225.9 2.8 102.3 99.4 111.2 9.5 99.0 182.4 152.9 151.2 65.7 137.3 196.6 306.5 114.3 33.3 157.8 90.1 197.1 237.0 241.0 106.0 224.3 211.9 82.4 82.7 145.7 121.2 POLR2J "hRPB14, POLR2J1, RPB11, RPB11A, RPB11m" ENSG00000005075 "RNA polymerase II subunit J" P52435 7 102473118-102478907 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA046970 Approved Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA046970: AB_2679882" "unprognostic (1.11e-1)" "unprognostic (1.24e-2)" "unprognostic (1.46e-2)" "unprognostic (1.62e-1)" "unprognostic (1.90e-2)" "unprognostic (4.80e-2)" "unprognostic (6.47e-2)" "unprognostic (4.26e-2)" "unprognostic (3.46e-1)" "unprognostic (1.53e-3)" "unprognostic (4.46e-2)" "unprognostic (7.32e-2)" "unprognostic (7.13e-2)" "unprognostic (2.45e-1)" "unprognostic (4.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" 54.8 87.0 85.3 36.5 87.4 90.0 51.7 88.2 108.0 48.3 83.2 59.1 46.4 48.1 54.7 60.0 46.5 32.7 125.8 85.3 89.6 71.2 99.4 43.3 46.1 89.2 87.2 59.3 58.6 62.9 66.4 32.5 87.4 59.7 33.9 17.8 58.6 38.2 195.7 56.5 51.1 28.3 88.3 59.1 63.6 43.6 90.2 53.2 56.0 127.7 40.1 51.1 48.1 88.4 143.4 143.0 96.2 127.5 89.2 68.5 70.4 77.4 82.3 111.2 94.2 131.1 108.4 65.7 145.9 108.7 160.2 74.8 89.8 95.6 67.8 123.3 160.4 65.9 101.2 129.1 108.9 128.5 94.6 89.6 117.4 100.1 55.8 72.5 100.8 138.3 156.8 190.0 92.5 439.6 212.9 228.5 89.5 141.4 182.2 100.1 94.4 194.0 91.2 93.6 81.4 135.6 93.5 176.1 113.9 97.3 79.1 155.3 82.3 125.0 160.0 198.4 154.5 116.5 183.6 171.0 111.3 157.8 149.1 180.3 116.5 199.5 90.5 122.5 86.2 137.6 96.0 101.0 93.8 122.9 81.4 81.8 174.6 84.7 115.5 127.5 140.8 128.9 85.3 87.4 88.2 108.0 85.3 89.6 89.2 87.2 87.4 88.3 90.2 88.4 87.9 35.3 46.7 17.9 91.1 95.0 113.5 190.7 79.1 37.0 149.6 195.2 193.2 81.5 107.4 125.0 12.5 197.7 93.0 241.7 273.9 139.0 53.1 84.1 64.4 86.8 103.0 128.2 5.6 199.6 195.5 94.4 78.0 73.2 43.7 90.7 86.0 203.5 202.5 35.3 6.2 164.0 146.5 111.0 107.6 43.2 127.1 99.5 142.3 4.7 154.0 171.3 127.7 8.5 10.8 191.8 281.6 110.6 111.4 128.9 236.3 242.0 107.0 46.7 52.6 76.9 113.2 117.1 229.3 114.3 116.1 182.1 91.4 114.5 131.2 153.9 POMGNT1 "FLJ20277, LGMD2O, MEB, MGAT1.2" ENSG00000085998 "Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)" Q8WZA1 1 46188682-46220305 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044518 Approved NA NA 17000000 "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "HPA044518: AB_10795985" "unprognostic (4.59e-3)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (3.20e-1)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.82e-1)" "unprognostic (5.74e-2)" "unprognostic (5.37e-2)" "prognostic favorable (4.27e-4)" "unprognostic (5.86e-2)" "unprognostic (4.39e-2)" "unprognostic (4.99e-3)" "unprognostic (1.72e-1)" "unprognostic (2.16e-2)" "unprognostic (2.36e-1)" 22.5 40.4 45.8 14.9 51.9 5.5 23.7 52.7 50.4 26.3 44.5 23.9 21.5 24.1 31.1 18.7 26.2 17.8 83.3 45.9 49.8 36.5 40.7 24.0 13.6 55.0 53.3 21.9 29.5 87.5 47.3 20.8 53.8 37.9 17.9 21.8 24.8 27.5 73.9 23.2 19.6 27.8 51.2 24.6 30.3 37.2 50.9 18.8 37.9 48.1 16.2 27.8 21.0 61.0 37.7 39.6 47.3 46.0 51.0 55.3 60.9 49.3 82.7 65.9 51.5 22.6 30.5 34.6 79.7 82.3 112.3 21.1 34.2 70.5 39.3 45.4 38.6 27.3 34.2 34.3 44.6 21.3 25.8 56.2 90.5 73.7 68.2 118.0 68.0 46.6 32.9 21.9 108.9 26.2 37.8 15.3 39.2 21.5 54.7 27.2 48.4 32.7 58.2 45.9 17.9 64.1 45.7 52.1 70.7 67.4 34.8 29.8 50.0 49.2 43.5 56.4 96.4 54.7 65.3 16.1 75.1 20.8 53.5 0.0 1.1 1.2 3.3 2.1 2.2 1.4 2.2 2.6 1.6 2.6 4.1 3.2 0.0 6.2 4.1 4.6 2.5 1.4 45.8 51.9 52.7 50.4 45.9 49.8 55.0 53.3 53.8 51.2 50.9 61.0 12.0 12.8 40.4 15.0 11.7 8.4 40.4 31.0 13.6 38.9 18.5 14.9 44.5 21.5 30.1 35.0 50.1 25.2 17.5 13.9 13.7 39.3 47.6 15.3 13.7 17.5 27.0 9.0 19.4 39.9 27.4 14.8 7.1 27.1 27.1 25.2 14.6 20.5 15.6 26.9 20.6 12.6 16.2 14.6 6.4 15.6 20.2 10.6 24.9 8.4 18.0 21.9 19.6 19.6 33.7 38.7 14.5 13.2 16.9 44.4 19.0 22.8 21.2 36.4 13.1 16.4 16.4 11.2 12.9 12.7 7.5 23.4 13.6 19.0 17.4 33.0 POMP "C13orf12, HSPC014, UMP1" ENSG00000132963 "Proteasome maturation protein" Q9Y244 13 28659104-28678959 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026995 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA026995: AB_1845546" "unprognostic (2.00e-1)" "unprognostic (3.56e-2)" "unprognostic (2.26e-1)" "unprognostic (3.15e-1)" "unprognostic (8.58e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (2.71e-3)" "unprognostic (2.50e-2)" "unprognostic (9.90e-2)" "unprognostic (4.35e-2)" "unprognostic (4.83e-2)" "unprognostic (4.93e-1)" "unprognostic (1.39e-3)" "unprognostic (1.70e-2)" "unprognostic (9.41e-2)" "unprognostic (1.03e-2)" "unprognostic (9.81e-2)" 78.9 71.6 77.5 62.9 78.5 66.4 66.7 82.1 101.1 45.1 77.8 66.6 57.0 44.4 78.9 68.7 43.4 46.2 126.3 78.1 83.6 94.1 110.9 65.6 65.4 82.2 83.4 32.9 46.6 51.7 41.7 100.3 83.2 46.6 66.3 56.2 45.1 50.7 175.6 48.5 58.4 57.2 83.6 61.2 54.9 70.0 81.0 64.6 51.4 114.6 70.1 74.0 46.9 86.3 103.4 124.9 129.9 153.1 145.3 161.3 120.3 232.1 203.8 225.5 179.5 245.7 228.7 181.7 136.3 178.6 241.7 150.3 170.7 179.3 307.5 137.7 131.9 171.7 130.1 191.1 203.0 209.6 136.0 131.2 181.9 162.5 149.5 122.3 181.6 139.7 222.2 72.5 291.5 182.5 178.4 295.6 226.1 319.0 146.1 169.6 199.3 122.2 259.6 160.7 152.1 117.1 104.0 147.4 162.2 161.5 103.1 238.5 166.2 108.7 111.2 172.3 195.5 61.5 118.5 255.3 129.2 139.8 243.6 146.4 155.3 101.7 99.9 210.8 88.7 136.4 101.6 113.2 190.8 137.6 71.8 101.9 135.1 95.3 213.9 223.4 132.3 165.2 77.5 78.5 82.1 101.1 78.1 83.6 82.2 83.4 83.2 83.6 81.0 86.3 527.4 131.4 114.2 17.3 218.5 409.8 345.1 1106.2 124.1 110.1 194.3 229.9 806.2 204.5 523.9 239.1 54.2 660.4 255.5 410.0 600.7 566.3 1156.6 266.7 235.8 486.2 228.7 271.5 23.4 699.5 974.0 281.8 128.9 293.0 207.3 181.6 434.1 538.7 780.7 97.6 22.4 315.0 585.9 431.0 673.7 533.7 201.0 407.1 300.6 29.0 612.6 294.7 228.6 13.6 26.1 755.1 414.0 233.6 228.1 443.5 491.8 922.5 472.8 121.8 322.1 193.8 494.6 625.5 240.3 230.1 416.3 972.4 202.7 234.7 335.5 494.3 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706121-100707486 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 25.6 31.7 30.1 18.1 31.6 33.9 26.6 33.4 38.6 24.2 23.8 27.9 19.3 27.7 11.0 34.0 21.3 9.8 37.6 32.3 30.8 25.8 67.1 18.2 17.3 30.1 27.8 18.1 31.3 16.6 22.8 16.6 30.8 22.6 9.2 9.6 29.0 13.5 69.0 50.2 22.3 12.1 29.4 22.7 26.4 12.5 29.1 15.6 16.8 31.9 12.0 25.4 24.9 33.9 115.7 115.3 47.2 78.4 25.1 23.9 92.0 65.6 32.4 73.7 73.1 159.8 71.0 97.5 105.1 30.0 81.4 70.4 70.1 79.5 36.8 82.7 212.4 44.9 75.0 166.5 42.1 69.2 49.8 27.6 30.2 76.2 74.8 20.9 41.6 68.9 157.4 77.8 39.8 330.4 158.0 232.9 135.2 77.8 164.4 123.6 50.0 159.4 45.3 65.2 90.4 92.3 54.5 156.2 78.7 42.0 50.0 66.2 41.3 92.0 117.7 191.0 127.6 34.0 99.4 175.8 61.0 115.1 104.6 106.3 63.2 72.4 54.7 64.7 50.7 60.3 54.6 54.3 55.3 47.7 49.5 52.0 39.0 78.9 70.3 51.2 69.8 62.5 30.1 31.6 33.4 38.6 32.3 30.8 30.1 27.8 30.8 29.4 29.1 33.9 30.5 19.2 17.0 2.9 29.7 105.0 32.0 57.2 56.3 26.1 61.6 64.1 27.9 37.1 31.5 35.0 6.2 148.2 25.8 51.8 93.9 75.4 2.1 31.2 32.3 37.2 40.2 50.1 5.2 87.4 181.3 37.3 25.0 35.1 17.7 32.4 33.5 99.0 66.1 32.0 6.0 61.7 67.1 27.3 40.7 7.9 42.0 22.4 56.9 2.8 38.7 41.8 41.2 4.0 5.8 92.2 47.6 37.2 55.1 75.6 69.8 86.1 27.8 21.3 46.0 29.8 52.2 9.2 45.5 74.7 119.2 139.3 27.2 39.9 55.8 43.5 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 44.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 99.4;Hepatocytes: 144.5;Proximal enterocytes: 93.2;Rod photoreceptor cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 10.3;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;granulocytes: 10.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB075701: , HPA058901: AB_2683849, HPA067049: AB_2685770" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favorable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 7.9 6.3 9.6 4.5 12.7 6.6 3.8 9.5 6.9 4.1 23.5 11.8 18.4 3.8 3.6 7.7 4.1 4.4 26.3 7.7 8.8 22.4 33.2 4.0 3.4 11.0 11.2 11.2 8.2 7.4 2.6 4.3 10.0 6.2 9.1 18.2 7.8 5.7 26.2 7.7 18.4 4.3 8.6 4.4 6.1 1.3 11.7 3.7 7.0 44.6 3.9 5.1 4.0 10.5 7.8 1.9 2.4 8.4 13.0 8.3 5.3 6.7 13.2 7.0 7.2 3.8 3.7 2.8 3.3 15.6 6.5 3.5 7.1 8.7 6.3 8.1 8.9 8.7 4.8 8.0 8.1 6.0 14.3 6.6 6.9 5.2 11.8 6.0 1.5 6.3 3.2 6.4 6.6 2.0 6.8 2.2 0.3 6.5 1.9 8.0 8.6 3.6 4.7 4.6 2.4 7.0 2.6 2.4 8.0 3.2 2.7 4.6 2.6 7.3 7.7 6.7 2.9 6.3 4.0 1.2 11.4 6.6 2.3 1.4 0.8 10.3 1.0 1.0 0.8 0.8 0.5 0.5 0.6 1.0 0.6 0.4 0.7 0.7 0.7 3.1 1.4 0.2 9.6 12.7 9.5 6.9 7.7 8.8 11.0 11.2 10.0 8.6 11.7 10.5 15.0 3.2 13.6 49.6 8.0 23.3 15.0 7.8 9.1 15.0 14.3 11.4 99.4 22.8 8.9 7.3 62.6 8.0 18.4 58.8 9.8 10.3 0.6 9.4 26.4 15.5 19.9 32.0 1.4 16.6 6.7 16.0 14.8 18.4 5.1 19.1 22.5 144.5 8.8 5.0 13.8 31.4 0.0 24.8 10.2 1.1 19.6 10.4 3.6 10.3 12.2 16.0 8.2 19.6 27.2 13.0 24.5 30.1 10.6 19.1 93.2 40.8 5.0 148.0 6.6 31.0 15.8 0.7 1.7 19.3 34.2 3.0 9.6 14.6 37.9 19.9 PPFIA4 ENSG00000143847 "PTPRF interacting protein alpha 4" O75335 1 203026498-203078740 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.8;heart muscle: 22.0;skeletal muscle: 18.9" "Group enriched" "Detected in some" 4 "Astrocytes: 12.7;Cardiomyocytes: 35.3;Excitatory neurons: 36.9;Inhibitory neurons: 31.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebellum: 58.8;cerebral cortex: 37.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 8.0;hTERT-RPE1: 13.1;RH-30: 13.6;U-266/70: 8.5;U-87 MG: 12.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053419, HPA054132" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA053419: AB_2682143, HPA054132: AB_2682393" "unprognostic (2.83e-1)" "unprognostic (2.34e-3)" "unprognostic (3.38e-5)" "unprognostic (3.19e-1)" "unprognostic (6.58e-2)" "unprognostic (5.36e-2)" "unprognostic (7.49e-8)" "unprognostic (4.65e-1)" "unprognostic (6.01e-4)" "unprognostic (1.29e-1)" "unprognostic (7.70e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.73e-8)" "unprognostic (6.82e-3)" "unprognostic (9.96e-2)" "unprognostic (1.11e-1)" "unprognostic (4.28e-2)" 0.5 0.6 9.5 0.4 4.2 1.0 0.6 58.8 37.4 3.5 0.0 1.4 0.5 2.3 2.4 1.1 1.0 1.7 22.0 7.6 0.0 5.3 0.3 0.8 0.2 2.2 0.0 0.9 0.1 0.4 1.6 2.8 1.5 1.0 0.2 7.2 1.4 0.6 18.9 2.0 0.8 1.2 0.0 1.6 0.8 3.2 2.5 0.4 0.5 12.0 0.2 0.6 2.0 3.1 8.0 0.0 0.1 1.9 0.0 0.3 0.3 0.4 0.9 0.7 3.2 0.4 0.3 0.4 1.6 1.8 0.2 0.9 0.6 1.5 1.5 0.0 0.6 0.1 0.0 0.0 0.1 0.0 1.0 2.5 0.1 0.4 0.0 13.1 0.0 1.6 0.1 0.3 6.5 1.1 0.6 1.0 0.9 0.0 0.3 1.4 13.6 2.3 0.0 0.0 2.6 3.3 0.8 0.2 1.1 1.2 0.2 0.6 0.0 4.8 2.8 0.1 0.1 8.5 0.2 0.1 12.4 0.7 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 4.2 58.8 37.4 7.6 0.0 2.2 0.0 1.5 0.0 2.5 3.1 0.1 0.0 0.0 12.7 0.1 0.0 0.1 3.7 0.6 5.1 0.5 0.3 35.3 0.0 0.9 0.0 6.2 0.1 0.1 0.0 0.0 0.9 2.7 0.4 0.3 0.6 0.0 0.0 36.9 0.0 0.4 1.7 0.0 0.7 0.0 1.8 0.7 0.0 0.3 6.7 31.9 0.1 0.0 0.0 0.0 3.6 0.3 0.7 0.0 4.7 1.9 1.5 1.0 5.5 1.9 0.4 0.1 1.9 0.0 0.1 0.0 0.1 1.0 1.5 0.0 1.1 0.8 0.6 1.4 0.3 0.0 0.3 0.1 0.1 0.0 0.0 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709127-158723396 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 480000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 26.8 38.3 38.0 24.4 40.2 25.1 22.8 40.4 77.6 25.4 46.4 33.9 50.6 24.2 19.0 27.7 24.1 18.8 49.6 40.1 44.2 39.5 87.6 19.8 28.6 39.0 39.4 24.2 31.7 17.0 28.6 21.6 40.2 23.5 20.3 36.2 23.3 18.7 88.9 36.1 45.3 18.9 39.6 29.1 29.0 24.1 42.2 24.3 23.9 45.5 25.8 27.4 24.0 46.9 46.7 42.3 41.8 57.7 60.7 45.2 63.1 44.9 24.3 40.3 30.4 55.4 30.9 48.9 19.7 42.0 63.4 35.1 127.9 51.5 48.8 162.9 44.4 87.5 36.5 76.9 46.8 55.6 63.0 28.9 41.2 34.6 51.5 52.0 44.6 81.9 111.0 84.4 45.5 44.6 80.0 49.9 57.9 75.5 55.8 35.9 20.7 41.7 44.6 23.0 70.2 47.1 33.8 69.2 65.6 60.0 31.9 52.2 43.7 40.1 45.3 44.7 60.2 48.3 107.2 62.0 51.1 59.4 41.1 68.8 23.9 55.2 31.1 35.4 36.0 22.3 30.2 29.1 26.4 25.4 30.9 32.0 32.9 40.5 37.7 26.9 37.0 28.0 38.0 40.2 40.4 77.6 40.1 44.2 39.0 39.4 40.2 39.6 42.2 46.9 29.2 6.4 13.4 13.1 24.8 10.1 29.7 17.5 9.1 30.2 19.1 20.8 59.7 25.8 27.9 27.6 22.9 41.5 38.7 17.1 37.2 39.2 39.0 66.1 39.9 25.1 19.6 17.4 24.3 23.0 49.5 24.3 14.3 28.5 32.3 24.4 17.2 18.5 41.9 75.7 28.6 28.3 22.4 17.0 14.7 23.1 20.5 26.0 14.2 9.4 51.6 23.3 48.4 15.1 28.3 29.5 27.4 22.6 22.3 31.6 39.7 33.7 62.3 32.3 6.6 17.7 58.2 96.0 77.5 16.9 11.8 47.6 33.7 33.7 32.0 20.2 PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36874803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 58.7;Extravillous trophoblasts: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062916 Supported Nucleoli NA NA 21000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli "HPA062916: AB_2684904" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-3)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (2.01e-1)" "unprognostic (3.37e-2)" "prognostic favorable (4.90e-4)" "unprognostic (6.58e-2)" "unprognostic (5.49e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-2)" 12.4 21.7 20.3 19.1 21.9 11.4 18.4 22.6 27.3 15.0 23.8 14.7 13.2 15.7 19.1 17.0 23.0 10.7 42.8 20.0 25.2 18.9 21.5 10.5 21.9 22.0 22.0 17.7 14.3 21.7 12.0 22.3 23.3 16.8 17.6 29.1 19.5 17.6 18.5 9.5 11.3 22.9 24.1 9.5 12.9 23.2 22.2 18.6 33.2 20.7 24.6 20.5 8.0 22.8 69.2 50.0 111.2 78.5 19.7 31.5 77.5 60.9 41.0 82.7 70.0 89.7 39.7 87.7 75.5 41.9 105.5 55.4 135.1 92.7 96.2 81.3 114.6 102.7 33.6 147.7 53.5 89.3 40.8 24.7 48.7 62.3 118.9 31.8 75.5 79.1 202.4 48.0 63.3 71.2 101.9 69.8 92.3 108.5 57.9 79.4 100.2 92.0 63.2 53.5 140.0 68.5 41.8 51.4 102.5 83.5 76.3 100.2 44.0 66.7 69.0 58.5 98.8 57.0 145.2 153.0 23.7 183.7 139.4 1.6 4.8 1.3 14.7 6.2 19.7 10.3 12.1 13.9 9.2 7.4 13.4 15.9 1.2 7.3 3.4 7.8 10.2 9.8 20.3 21.9 22.6 27.3 20.0 25.2 22.0 22.0 23.3 24.1 22.2 22.8 5.7 6.4 7.5 2.9 10.8 3.1 18.6 12.2 5.7 16.9 9.0 10.5 45.8 8.6 8.3 5.5 4.2 58.7 6.6 3.3 23.5 25.7 32.0 10.3 14.2 12.3 3.6 22.7 6.5 20.3 72.3 12.2 7.7 7.7 10.8 16.3 5.0 8.2 30.1 16.8 8.6 11.4 4.1 3.3 3.6 11.7 6.8 6.4 7.2 1.9 9.2 41.0 11.3 7.5 5.4 22.1 5.5 12.4 15.0 13.5 3.3 17.1 13.5 15.5 6.6 6.1 12.8 25.7 51.0 10.6 4.5 25.3 9.2 21.1 11.9 8.6 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46347087-46392981 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol NA NA 120000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Cytosol" "CAB022641: , HPA029065: AB_10610284, HPA056933: AB_2683278" "unprognostic (8.25e-2)" "unprognostic (7.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.30e-2)" "unprognostic (5.92e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.25e-2)" "unprognostic (5.56e-2)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" 27.4 37.5 27.7 17.7 29.3 14.2 26.3 28.4 36.5 28.0 27.7 31.3 16.8 34.9 9.8 30.4 31.7 13.3 56.4 29.8 28.6 29.1 32.7 28.0 19.7 32.3 28.2 24.7 23.7 32.5 36.6 15.8 33.3 23.7 15.4 14.4 23.0 18.2 58.9 27.5 25.9 20.8 26.2 33.5 33.6 16.9 30.3 20.5 26.2 45.7 15.0 27.7 26.3 28.5 61.9 114.9 66.0 50.1 48.3 50.9 30.6 75.4 59.6 88.2 78.2 82.4 47.9 94.3 39.9 54.0 48.4 49.9 86.2 88.5 24.7 65.9 120.5 76.4 80.9 59.4 54.5 106.6 52.8 47.8 40.9 62.1 45.9 34.2 77.2 79.3 76.0 47.3 49.4 67.5 59.5 203.4 50.2 109.6 61.7 89.0 56.6 76.5 52.8 81.8 93.1 69.7 62.6 78.8 26.9 28.6 49.7 67.8 65.5 38.3 64.3 29.1 79.1 38.0 93.0 111.5 41.7 89.4 65.9 0.0 10.3 3.0 27.8 18.0 17.8 15.1 12.8 22.0 16.8 11.7 12.2 16.8 0.2 22.0 23.4 11.7 14.3 15.4 27.7 29.3 28.4 36.5 29.8 28.6 32.3 28.2 33.3 26.2 30.3 28.5 28.1 6.4 12.5 22.9 16.5 9.4 16.6 20.9 19.9 19.7 13.1 13.5 5.6 44.3 14.2 16.5 16.7 26.4 12.3 25.2 33.2 29.9 1.2 31.3 25.2 19.6 14.9 11.6 18.5 19.5 36.2 17.6 26.0 19.6 4.5 18.6 24.3 24.9 21.6 16.8 23.2 17.0 22.4 12.3 8.2 3.2 17.4 11.9 16.0 11.2 12.1 21.0 17.5 17.6 14.5 26.4 17.0 18.4 25.5 12.1 16.3 21.4 14.6 17.9 39.5 14.6 19.9 26.6 32.0 20.8 13.2 25.7 20.4 23.1 25.0 11.7 PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.6" "Cell type enhanced" "Detected in all" "Late spermatids: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA051066: AB_2681333" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (3.93e-2)" "unprognostic (8.54e-2)" "unprognostic (9.08e-3)" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-3)" "unprognostic (9.99e-3)" "unprognostic (3.56e-2)" "unprognostic (2.96e-1)" "unprognostic (4.89e-1)" "unprognostic (1.93e-1)" "unprognostic (9.23e-2)" 22.8 35.9 46.0 9.8 48.1 8.7 19.3 48.6 50.6 15.1 54.1 29.0 25.2 12.6 16.3 25.8 11.3 9.8 101.4 45.8 46.9 27.0 71.5 12.7 9.2 47.6 47.3 11.0 41.6 21.2 23.1 8.2 47.4 19.3 21.4 15.5 29.1 14.7 126.6 20.6 22.1 14.8 46.7 23.6 27.1 31.3 49.0 11.0 17.9 107.1 9.9 23.1 16.3 46.4 21.7 16.6 16.2 31.3 49.3 19.2 22.6 37.8 15.1 32.5 18.7 46.6 20.6 23.3 20.2 38.0 29.3 19.5 25.8 22.7 23.0 36.2 28.2 36.7 21.4 35.2 15.3 20.3 33.7 25.0 13.5 29.2 15.4 9.4 30.5 39.0 32.4 46.1 37.8 41.9 51.7 34.0 5.2 93.7 74.2 31.0 68.6 71.8 18.6 19.0 34.5 12.3 18.1 42.5 15.7 17.3 22.5 15.7 18.9 37.6 16.6 32.9 31.8 52.2 43.9 22.3 24.0 39.6 15.7 15.6 35.0 35.4 24.8 84.3 20.1 17.5 23.8 23.6 36.3 21.8 22.3 19.5 5.0 39.2 105.3 73.3 31.1 48.2 46.0 48.1 48.6 50.6 45.8 46.9 47.6 47.3 47.4 46.7 49.0 46.4 21.7 9.6 4.6 10.1 11.0 15.6 11.3 34.5 4.6 15.2 23.3 23.9 62.6 15.7 20.0 14.7 8.4 25.7 25.4 44.7 72.4 23.3 57.3 12.1 9.3 17.7 32.3 4.2 6.9 46.9 47.2 20.4 13.7 6.0 28.6 4.8 30.7 63.0 49.1 11.8 6.9 47.7 44.7 25.5 14.0 144.3 16.8 19.3 16.0 1.9 7.2 31.4 21.6 6.0 7.0 23.2 31.2 16.1 29.2 10.7 101.4 65.2 15.8 28.3 32.9 19.1 19.1 61.5 21.1 30.1 24.0 13.5 9.7 27.2 50.2 15.4 PRDX2 "MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA" ENSG00000167815 "Peroxiredoxin 2" P32119 19 12796820-12801800 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1316.7;Erythroid cells: 3153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008713 Approved NA NA 800000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" "CAB008713: AB_1620974" "unprognostic (1.12e-1)" "unprognostic (1.98e-3)" "unprognostic (8.58e-2)" "unprognostic (4.40e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (2.44e-1)" "unprognostic (2.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.26e-2)" "unprognostic (9.18e-2)" "prognostic favorable (5.66e-11)" "unprognostic (7.01e-3)" "unprognostic (2.15e-1)" "unprognostic (3.51e-2)" "unprognostic (1.41e-1)" 199.0 622.0 350.8 88.3 366.6 686.7 159.7 408.2 461.5 167.8 365.6 208.1 251.7 178.8 144.5 271.8 153.5 133.9 704.0 369.6 400.0 287.7 310.2 109.1 118.3 407.5 380.4 218.2 201.7 454.5 314.6 87.8 408.2 175.3 141.5 207.1 200.1 124.4 722.9 260.7 201.1 127.0 357.0 118.1 226.6 32.8 399.1 181.3 156.3 847.9 129.2 163.6 171.6 355.5 420.4 1.1 553.9 721.3 79.5 54.2 408.4 189.0 188.0 253.9 143.4 438.1 102.8 122.7 430.9 185.0 30.2 389.5 354.7 309.7 72.9 528.5 561.4 222.6 537.4 665.1 212.4 0.7 1.4 233.6 140.5 191.1 93.0 327.6 238.8 255.3 485.7 187.0 98.7 763.3 500.1 190.2 409.1 289.6 789.4 485.8 0.7 593.0 343.1 450.0 683.8 538.5 449.5 454.9 153.7 100.7 408.0 318.0 105.7 188.2 156.9 526.7 417.7 226.3 242.1 573.5 178.9 75.5 43.8 35.4 170.0 85.6 436.1 129.4 460.6 375.2 589.8 446.2 211.6 288.5 594.7 460.9 22.4 213.2 148.0 124.5 697.4 686.6 350.8 366.6 408.2 461.5 369.6 400.0 407.5 380.4 408.2 357.0 399.1 355.5 192.2 22.4 36.7 39.5 117.5 221.3 255.6 877.7 187.2 317.9 271.2 322.2 37.1 265.9 347.7 279.6 100.1 692.8 83.5 367.4 1316.7 329.5 3.1 138.6 218.5 130.3 333.7 3153.4 31.8 167.2 558.8 204.3 214.6 197.7 47.0 466.0 137.8 489.7 234.0 215.4 50.8 360.7 754.8 63.8 128.8 13.0 293.9 58.7 281.1 23.4 61.4 531.2 56.7 41.7 29.1 179.6 250.6 321.2 263.4 169.3 765.6 1097.9 152.7 373.2 157.8 142.4 273.2 4.8 7.7 368.5 229.4 508.4 144.4 816.6 475.7 243.1 PRDX5 "ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10" ENSG00000126432 "Peroxiredoxin 5" P30044 11 64318121-64321811 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 2430.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008661, HPA037915, HPA037916" Enhanced Supported Mitochondria NA NA 6900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB008661: AB_1620988, HPA037915: AB_2675735, HPA037916: AB_2675736" "unprognostic (2.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (9.43e-2)" "unprognostic (6.71e-3)" "unprognostic (1.08e-3)" "unprognostic (3.11e-1)" "unprognostic (9.30e-2)" "unprognostic (1.07e-3)" "unprognostic (1.57e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.24e-5)" "unprognostic (8.19e-2)" "unprognostic (2.30e-1)" "unprognostic (9.63e-2)" "unprognostic (5.03e-2)" 181.8 400.3 346.0 112.7 342.6 285.7 170.1 375.9 429.4 227.2 480.2 346.6 213.3 153.7 176.6 448.5 400.3 120.7 467.4 340.4 384.6 377.1 280.3 217.2 110.1 382.8 373.3 246.0 224.9 254.5 313.3 164.1 387.0 165.5 299.6 109.0 286.2 164.4 504.0 181.1 226.1 97.1 365.2 162.9 313.9 150.1 377.8 167.7 354.5 439.6 137.8 192.5 244.8 346.4 225.3 453.4 267.9 444.5 284.3 424.4 308.5 274.9 442.3 199.8 247.4 332.9 451.8 329.2 467.0 447.4 712.6 503.5 253.3 589.4 125.8 456.6 200.8 333.3 728.8 386.3 581.0 127.8 271.3 432.4 757.2 334.9 337.8 387.6 308.4 380.6 191.5 755.6 285.5 572.0 220.9 547.8 402.6 356.5 573.9 210.9 274.5 1178.8 760.1 442.9 224.7 424.9 230.8 506.8 818.8 254.3 370.5 283.3 298.3 281.8 258.6 326.7 123.1 383.1 490.8 392.4 340.7 253.7 223.6 703.9 465.4 630.7 251.0 432.9 218.3 393.5 229.0 205.1 369.8 409.0 224.5 225.9 802.3 368.5 399.0 487.9 297.1 639.6 346.0 342.6 375.9 429.4 340.4 384.6 382.8 373.3 387.0 365.2 377.8 346.4 213.7 266.0 463.4 17.6 182.1 326.5 760.2 1591.9 405.2 159.0 266.2 435.9 617.6 371.8 931.2 450.6 70.9 1122.2 185.8 846.1 1612.1 788.4 79.6 865.2 221.3 204.7 801.9 200.6 12.4 1039.2 1144.0 296.1 365.4 285.9 104.7 299.8 205.6 405.2 476.9 92.5 14.0 1041.6 1072.1 206.5 261.0 294.9 279.0 210.8 435.8 8.4 339.7 309.6 278.1 14.1 15.3 1487.3 641.3 226.8 288.9 401.3 922.4 1468.5 2430.7 150.3 197.2 176.2 433.1 150.2 333.9 482.8 257.7 978.9 165.2 713.3 1231.7 1077.1 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477330-173488815 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1315.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 340.7 157.5 169.5 68.3 181.3 100.1 211.2 197.6 210.1 112.3 164.8 189.1 46.4 108.8 206.3 127.9 149.8 71.9 261.8 184.1 196.6 184.4 482.5 116.7 72.2 181.0 198.3 115.5 114.4 217.5 67.4 70.7 187.5 152.1 221.6 53.9 85.6 99.0 563.5 106.6 59.8 160.2 175.8 70.7 135.2 119.1 176.7 70.7 106.0 382.4 79.0 99.5 109.8 185.5 420.3 127.7 204.7 230.9 778.5 372.7 169.5 843.9 284.3 342.7 241.8 243.9 276.4 272.4 256.4 694.2 120.4 239.8 272.0 259.9 279.0 234.0 243.6 179.5 200.0 277.7 425.7 191.3 56.1 301.0 262.6 181.3 256.6 210.8 339.5 106.7 405.4 52.8 392.9 86.3 131.7 249.1 456.2 219.8 760.5 154.5 236.6 277.0 518.1 95.4 94.9 173.4 285.0 334.0 199.2 296.3 283.8 262.9 228.2 132.5 149.9 201.8 229.5 76.4 123.2 220.7 159.4 162.3 124.3 36.2 42.5 24.8 29.8 39.8 32.8 32.6 29.8 38.4 53.5 24.4 39.8 47.9 25.2 25.7 36.5 79.7 36.1 58.1 169.5 181.3 197.6 210.1 184.1 196.6 181.0 198.3 187.5 175.8 176.7 185.5 278.1 176.3 170.8 127.3 127.4 235.4 404.1 382.8 209.5 31.9 186.1 250.7 528.6 301.7 228.6 277.7 29.2 714.3 158.6 1315.9 860.8 178.6 237.5 206.9 226.8 191.8 142.1 449.5 13.8 202.3 939.1 307.0 111.6 200.0 348.6 216.6 214.2 1120.2 345.0 45.4 13.2 257.4 205.4 164.3 161.0 667.5 340.5 227.1 183.2 17.8 212.9 462.5 83.4 12.5 15.4 147.2 663.4 416.8 176.4 427.1 264.4 827.3 209.1 52.0 184.1 185.7 253.8 123.5 76.8 305.9 264.1 963.5 157.7 512.5 303.6 308.9 PREB SEC12 ENSG00000138073 "Prolactin regulatory element binding" Q9HCU5 2 27130756-27134666 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 369.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013582, HPA014133" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA013582: AB_1855694, HPA014133: AB_1855695" "unprognostic (2.32e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (4.96e-3)" "unprognostic (1.44e-1)" "unprognostic (9.89e-2)" "unprognostic (1.21e-3)" "unprognostic (1.24e-2)" "unprognostic (2.69e-1)" "unprognostic (2.33e-3)" "unprognostic (5.13e-2)" "unprognostic (4.14e-2)" "unprognostic (5.25e-2)" "unprognostic (1.28e-2)" 45.2 46.0 40.0 28.6 41.4 16.5 39.5 41.5 47.9 38.7 37.3 34.0 27.7 57.3 104.8 41.0 46.1 25.9 62.5 42.0 42.6 49.0 137.2 33.4 33.3 44.2 41.4 49.9 73.9 30.8 42.8 22.6 41.4 42.7 27.7 16.7 60.0 34.6 134.5 29.6 36.0 40.7 41.8 51.5 42.5 35.1 42.1 31.0 30.3 112.0 38.3 34.9 32.3 42.6 63.5 62.2 35.4 56.5 84.8 30.2 65.8 44.6 46.5 63.5 44.4 59.1 38.7 78.3 45.9 44.5 68.7 35.3 70.3 56.3 41.3 58.7 63.2 64.2 30.7 128.3 111.1 74.3 58.2 28.8 67.5 60.2 68.2 34.2 44.7 61.4 48.0 68.3 57.6 73.4 69.2 56.5 37.2 81.5 64.8 63.9 70.9 369.2 46.9 33.2 79.8 42.8 42.8 88.3 65.7 36.1 39.4 125.3 25.0 33.9 48.7 29.8 51.0 150.5 67.9 95.1 56.4 83.4 65.4 73.7 61.0 103.3 50.4 52.2 53.7 44.5 42.1 50.2 62.5 43.9 40.1 41.7 25.4 65.0 55.8 74.1 50.9 63.9 40.0 41.4 41.5 47.9 42.0 42.6 44.2 41.4 41.4 41.8 42.1 42.6 9.7 16.0 12.7 5.5 33.5 18.0 9.8 14.3 9.1 12.2 21.8 19.0 14.2 20.0 10.6 20.2 12.5 45.3 22.8 17.3 35.2 29.8 5.9 5.8 14.7 10.8 8.4 30.7 7.4 35.1 60.3 18.2 28.1 11.9 23.6 13.1 16.1 36.1 38.0 6.7 7.7 28.5 20.3 19.8 16.3 9.1 23.6 17.9 19.6 8.4 16.6 25.3 24.7 9.5 9.1 30.9 20.4 44.8 101.5 18.4 30.0 29.2 3.8 10.9 32.9 10.2 21.0 32.1 44.8 18.7 17.3 77.4 22.6 16.2 22.3 12.9 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 310.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 116.8;Theca cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 62.7 126.5 46.6 27.6 47.6 18.9 53.9 39.9 64.2 53.2 29.5 59.0 20.9 56.9 28.5 41.8 53.7 14.2 204.8 49.2 53.3 35.4 78.4 46.1 15.9 56.8 54.5 94.1 34.0 21.6 71.2 17.3 55.3 41.2 13.0 25.2 42.3 20.8 310.9 42.3 36.3 21.8 40.7 71.6 40.2 57.2 50.3 18.2 39.6 122.1 13.4 50.6 44.2 46.6 37.5 16.3 40.3 74.4 36.2 30.8 9.9 30.5 23.6 32.7 27.5 21.6 15.0 13.8 26.2 49.2 22.9 25.4 26.7 26.6 32.3 23.1 17.7 27.7 20.6 24.4 36.8 21.9 33.5 33.8 18.1 30.0 11.1 26.6 29.7 19.0 29.1 47.3 36.7 48.1 46.3 31.9 21.5 38.7 45.0 38.0 47.8 36.7 41.7 13.5 36.5 24.2 34.2 31.3 23.8 18.1 37.2 26.5 37.7 71.7 20.3 100.7 39.6 31.9 24.9 23.6 49.6 28.0 32.7 0.1 1.5 0.2 0.8 2.7 0.3 0.8 0.3 0.5 1.1 0.5 0.5 0.7 3.2 0.4 2.5 0.6 0.3 0.6 46.6 47.6 39.9 64.2 49.2 53.3 56.8 54.5 55.3 40.7 50.3 46.6 39.5 6.4 3.4 9.4 7.0 8.8 6.8 6.4 2.2 42.2 19.2 19.0 116.8 22.8 4.7 14.7 27.1 6.9 9.0 24.6 7.9 12.4 32.4 11.7 22.9 26.7 17.5 2.5 16.9 19.1 5.7 22.6 8.6 12.9 0.0 15.9 26.4 39.7 34.5 3.3 21.6 11.8 2.0 49.4 50.8 15.7 49.0 37.1 14.2 9.4 37.8 26.1 9.2 10.1 10.7 15.6 11.6 51.9 3.3 6.4 20.7 11.8 7.0 23.9 19.7 23.3 23.5 26.4 6.9 10.1 11.2 8.1 10.0 100.6 14.4 6.6 PRPF8 "hPrp8, Prp8, PRPC8, RP13, SNRNP220" ENSG00000174231 "Pre-mRNA processing factor 8" Q6P2Q9 17 1650629-1684867 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 252.3;Rod photoreceptor cells: 293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009941, CAB015457" Supported Enhanced Nucleoplasm NA NA 120000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB009941: AB_2171185, CAB015457: AB_831685" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-2)" "unprognostic (3.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.94e-2)" "unprognostic (6.58e-2)" "unprognostic (1.56e-1)" "unprognostic (4.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (2.45e-3)" "unprognostic (2.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" 78.5 128.7 82.6 45.7 85.0 70.5 78.6 93.2 121.3 98.5 98.7 93.5 33.0 94.5 44.1 85.3 94.2 30.8 100.9 84.4 84.0 78.2 91.2 84.2 52.8 83.6 82.1 131.6 78.3 82.7 130.4 44.7 86.2 89.7 44.5 115.6 78.1 49.1 146.7 92.6 84.2 51.7 80.9 98.2 80.5 100.1 81.5 83.9 89.0 80.1 61.6 96.9 84.3 88.0 104.0 240.7 149.0 116.1 120.8 90.4 107.9 78.2 109.5 160.3 122.4 208.2 50.0 150.0 73.2 150.5 113.4 152.9 356.3 139.5 181.6 99.4 170.0 124.3 187.1 161.0 73.5 145.4 138.9 86.0 91.2 194.8 146.7 84.5 146.1 106.2 121.1 126.6 117.9 112.7 114.4 117.4 97.0 97.7 74.4 218.4 82.3 80.7 63.1 121.1 71.0 103.8 145.0 61.5 69.3 121.6 87.4 91.3 122.1 91.7 78.3 130.2 176.1 46.6 46.7 101.9 81.6 108.1 121.6 23.1 8.9 10.1 19.1 14.4 23.6 17.5 17.7 20.9 15.7 18.3 16.7 20.0 9.0 14.2 21.7 25.2 23.2 11.2 82.6 85.0 93.2 121.3 84.4 84.0 83.6 82.1 86.2 80.9 81.5 88.0 45.7 60.9 84.3 24.5 72.8 30.1 30.0 42.5 56.9 128.0 31.8 34.4 39.4 42.9 53.9 47.8 252.3 43.3 66.6 42.9 7.9 35.5 11.8 45.4 38.8 46.3 36.5 73.0 23.6 40.9 26.7 48.3 56.1 40.3 52.6 55.9 37.9 38.7 39.8 72.3 29.3 40.2 32.6 40.1 26.5 11.2 73.3 42.6 19.6 19.7 48.3 55.9 46.4 21.6 19.0 42.7 36.5 52.3 70.0 31.4 48.7 18.3 51.3 293.2 72.3 65.4 44.8 100.4 99.1 57.3 27.8 39.5 62.8 50.2 50.3 31.5 PRUNE1 "DRES-17, H-PRUNE, HTCD37, PRUNE" ENSG00000143363 "Prune exopolyphosphatase 1" Q86TP1 1 151008420-151035713 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.0;Breast glandular cells: 9.8;Breast myoepithelial cells: 8.9;Collecting duct cells: 11.0;Granulosa cells: 8.9;Proximal tubular cells: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 169.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028411 Uncertain Supported Cytosol NA NA 41000 "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA028411: AB_10603229" "unprognostic (6.24e-2)" "unprognostic (2.24e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (6.91e-2)" "unprognostic (2.02e-1)" "unprognostic (2.12e-3)" "unprognostic (7.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.92e-2)" "unprognostic (1.73e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (3.48e-4)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-1)" 10.1 9.5 12.2 7.7 12.1 4.4 14.9 16.1 15.1 15.0 12.4 14.8 12.5 14.8 15.6 12.4 16.0 9.2 33.4 12.4 12.6 18.8 14.3 10.8 10.8 12.0 12.5 17.2 10.7 20.9 12.6 7.1 11.9 12.2 14.5 10.8 13.2 14.4 29.4 11.5 12.0 14.1 11.9 11.2 11.2 18.3 12.8 16.2 32.5 21.4 12.6 13.7 11.9 13.5 11.0 11.6 20.2 19.3 24.3 6.6 10.9 5.1 11.2 18.7 16.4 14.1 13.0 22.2 21.7 6.9 5.5 15.5 19.9 13.4 14.6 24.5 22.6 26.6 11.8 20.4 13.5 17.5 13.0 8.4 24.7 10.2 9.5 15.4 9.2 29.4 21.1 18.3 8.9 26.2 27.2 14.1 18.7 39.7 15.0 24.2 12.8 21.5 13.4 14.9 28.7 23.5 17.5 23.5 16.1 28.3 32.6 25.7 6.3 6.6 7.8 7.5 8.1 44.1 40.0 169.1 6.5 13.0 16.9 19.1 8.1 17.8 16.4 7.8 19.8 14.4 18.1 18.6 11.9 15.4 21.7 17.5 18.6 18.8 12.2 6.4 18.5 22.3 12.2 12.1 16.1 15.1 12.4 12.6 12.0 12.5 11.9 11.9 12.8 13.5 4.5 6.4 13.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 9.8 8.9 0.0 0.0 3.1 11.0 0.0 4.1 3.2 0.0 0.0 6.0 0.0 4.3 7.8 2.1 0.0 0.0 0.0 5.7 4.8 2.5 0.0 6.4 0.0 8.9 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 5.6 0.0 0.0 1.0 0.0 0.0 8.9 2.9 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 5.1 2.8 4.8 0.0 0.0 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PSMB6 "DELTA, Y" ENSG00000142507 "Proteasome 20S subunit beta 6" P28072 17 4796144-4798502 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023312, HPA063656" Supported Supported Nucleoplasm,Cytosol NA NA 1400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA023312: AB_1855828, HPA063656: AB_2685078" "unprognostic (2.71e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (3.32e-3)" "unprognostic (8.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-2)" "unprognostic (7.47e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (5.27e-2)" "unprognostic (5.66e-2)" 92.7 107.8 130.1 82.2 133.7 126.9 107.0 138.1 141.2 92.6 137.4 116.3 76.9 101.9 150.9 140.6 99.2 68.3 201.6 132.8 138.1 134.8 184.6 86.2 90.1 135.7 134.1 63.7 99.3 173.3 82.5 119.8 138.7 84.8 118.3 62.6 100.0 114.2 358.6 114.9 77.0 135.3 136.0 90.4 103.8 76.6 133.5 147.4 88.7 339.5 140.5 110.6 89.2 140.3 279.8 478.2 251.6 216.4 209.9 188.1 289.7 144.1 300.1 431.3 336.0 358.7 220.5 215.0 277.9 348.1 246.5 273.8 388.0 404.4 418.0 281.9 409.7 128.0 315.3 422.7 242.0 133.5 194.4 178.3 305.1 377.4 355.7 241.5 426.5 335.8 199.4 316.6 336.1 331.8 237.4 221.8 214.1 356.2 328.2 261.9 178.7 284.6 326.6 185.3 146.9 179.9 206.6 158.9 148.6 261.4 194.5 147.2 205.1 210.8 158.9 286.4 355.2 130.8 191.8 132.9 301.3 242.1 259.3 410.6 603.3 343.2 347.5 589.9 355.9 668.6 373.1 384.0 624.9 640.8 319.8 329.3 210.5 424.4 549.4 585.5 556.2 817.2 130.1 133.7 138.1 141.2 132.8 138.1 135.7 134.1 138.7 136.0 133.5 140.3 156.3 134.6 113.3 8.5 118.3 229.2 184.1 410.8 112.1 65.5 124.6 153.4 454.8 141.5 253.9 134.3 16.7 587.3 142.8 178.0 358.1 321.6 245.2 110.9 108.1 164.7 148.4 183.7 7.6 349.9 418.2 171.5 105.5 116.0 105.2 156.1 99.6 235.4 346.3 32.0 7.2 173.0 311.3 111.7 272.1 52.9 109.6 159.8 236.5 4.7 298.9 183.4 109.2 9.0 16.9 351.3 163.4 123.0 244.7 191.7 188.6 564.6 193.3 81.3 111.7 119.8 486.8 175.1 84.7 178.6 277.2 664.5 125.9 172.6 177.7 217.3 PSMB7 Z ENSG00000136930 "Proteasome 20S subunit beta 7" Q99436 9 124353465-124415444 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052408, HPA054902" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No No 2100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA052408: AB_2681820, HPA054902: AB_2682635" "unprognostic (7.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (3.64e-3)" "unprognostic (2.83e-1)" "unprognostic (1.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.24e-3)" "unprognostic (9.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.67e-1)" "unprognostic (3.45e-1)" "unprognostic (1.93e-3)" "unprognostic (3.98e-2)" 115.7 180.4 129.4 103.9 136.9 189.7 122.6 132.7 144.8 99.8 119.6 103.5 98.7 102.9 147.0 139.1 94.6 87.2 212.0 135.8 137.0 150.9 222.9 91.4 112.7 138.2 139.5 101.6 142.2 143.4 74.7 120.2 138.2 94.8 107.8 81.0 114.3 75.0 277.8 166.2 98.3 92.7 131.5 91.7 115.3 155.2 137.8 147.6 91.3 205.3 124.6 110.5 104.2 135.0 344.4 411.7 275.8 336.4 190.4 224.8 396.1 325.3 447.6 461.7 315.1 546.3 327.1 389.2 256.8 307.4 457.2 480.2 346.7 345.4 420.0 375.0 299.3 245.3 673.3 460.0 428.5 491.6 234.3 270.8 299.6 483.7 478.5 355.1 394.3 345.5 507.9 269.8 362.4 600.0 355.9 329.5 409.7 519.6 581.5 309.8 411.4 457.2 331.5 221.9 323.7 263.6 310.4 394.0 498.4 268.7 454.8 212.7 315.9 297.5 240.7 384.9 499.0 289.9 873.7 394.9 498.1 297.8 429.1 162.7 201.5 154.5 128.3 211.4 138.9 177.8 145.7 142.5 221.1 159.7 138.2 135.9 87.0 185.3 206.8 187.5 226.0 264.8 129.4 136.9 132.7 144.8 135.8 137.0 138.2 139.5 138.2 131.5 137.8 135.0 73.1 76.9 77.6 26.1 88.0 194.1 184.4 309.1 39.9 41.5 113.9 97.5 147.3 134.4 150.0 69.9 22.9 441.4 83.0 146.9 330.6 351.3 404.6 105.7 93.8 123.8 141.2 93.8 38.4 392.7 356.7 112.3 52.5 90.3 104.6 130.8 107.1 277.3 237.2 33.7 31.9 162.5 160.7 122.1 148.4 472.8 139.1 92.5 199.3 33.7 168.5 119.7 113.3 30.7 44.8 393.6 143.7 125.3 69.9 158.0 173.6 484.7 135.7 61.6 85.5 133.8 221.2 330.6 190.4 60.4 218.9 488.7 81.4 135.8 181.2 201.3 PSMC5 "p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1" ENSG00000087191 "Proteasome 26S subunit, ATPase 5" P62195 17 63827152-63832026 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 596.6;Late spermatids: 1350.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017871, HPA064293" Enhanced Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA017871: AB_1857638, HPA064293: AB_2685234" "unprognostic (9.65e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-1)" "unprognostic (2.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (8.29e-3)" "unprognostic (1.24e-2)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" "unprognostic (2.17e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (9.54e-2)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" 90.4 99.0 134.8 80.9 137.5 82.4 80.6 141.3 159.0 79.6 130.2 106.1 68.0 80.1 112.3 104.9 83.2 59.4 107.5 136.2 139.3 120.9 112.7 68.1 93.0 140.5 140.2 63.3 71.0 161.1 82.5 75.5 141.2 81.4 84.4 85.3 73.4 86.7 236.2 121.5 70.6 90.3 137.7 82.4 84.5 73.3 139.6 93.3 86.4 168.7 108.0 93.4 79.6 138.9 240.1 369.1 233.9 172.9 171.4 174.7 202.8 225.3 197.0 327.1 243.8 390.3 154.7 158.7 154.7 241.6 246.0 182.8 239.1 228.5 383.5 136.8 289.7 330.3 288.9 362.4 180.1 336.0 230.4 177.5 171.4 291.9 266.6 139.1 263.7 180.9 258.4 210.2 284.9 450.7 279.4 237.4 215.6 266.3 330.0 248.9 445.5 244.3 249.0 270.9 203.2 274.1 158.6 313.9 152.3 254.4 306.8 197.8 238.8 360.3 329.9 161.5 482.6 220.5 335.2 250.4 225.8 255.7 241.5 105.1 120.4 149.4 164.1 176.3 222.8 142.7 191.6 179.3 140.0 122.0 161.3 183.1 37.7 167.4 206.3 108.6 272.1 216.1 134.8 137.5 141.3 159.0 136.2 139.3 140.5 140.2 141.2 137.7 139.6 138.9 97.9 51.3 78.6 8.5 82.7 94.6 145.0 206.3 71.7 84.9 71.1 79.1 156.0 110.1 139.6 68.0 18.8 250.4 85.1 98.8 246.5 195.2 596.6 75.4 69.4 104.7 90.9 107.7 7.9 214.5 187.2 101.4 69.3 68.1 90.2 53.3 86.4 130.9 162.9 72.3 7.9 92.7 197.4 89.8 85.0 1350.2 133.0 93.4 99.6 5.6 148.0 221.4 109.2 7.5 10.5 167.5 96.3 153.4 88.0 125.6 163.7 330.3 95.1 108.4 111.7 113.0 228.7 151.6 150.2 95.0 102.9 369.0 102.9 124.7 97.9 137.9 PSMD12 "p55, Rpn5" ENSG00000197170 "Proteasome 26S subunit, non-ATPase 12" O00232 17 67337916-67366605 "Disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023119 Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA 73000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules "Nucleoplasm, Cytosol" "HPA023119: AB_1855845" "unprognostic (6.06e-2)" "unprognostic (3.16e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.35e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.28e-2)" "unprognostic (3.72e-2)" "prognostic favorable (6.32e-4)" "unprognostic (2.63e-1)" "unprognostic (7.32e-3)" "prognostic unfavorable (4.73e-6)" "unprognostic (1.52e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" 14.8 13.9 11.2 11.4 12.2 12.5 11.9 15.0 19.4 9.4 9.7 10.4 8.2 10.5 10.9 12.5 7.6 9.7 13.7 12.6 17.2 14.9 28.0 9.4 10.8 17.8 17.8 9.1 15.6 14.8 7.6 11.0 18.9 10.7 11.6 8.9 10.0 7.7 35.8 10.3 8.7 11.3 12.9 9.4 11.2 14.4 16.0 12.1 10.3 29.1 15.1 14.7 8.0 12.5 63.8 38.5 29.2 32.2 21.9 26.3 40.6 44.2 27.9 47.8 42.0 40.4 27.4 36.6 28.0 35.9 37.4 37.0 51.1 45.1 70.7 17.8 38.5 43.2 29.9 41.1 28.6 44.7 25.0 29.6 29.4 45.3 35.2 21.2 47.6 27.8 57.4 21.0 45.0 43.5 41.0 42.6 35.7 30.0 50.1 20.9 75.6 32.5 36.1 52.0 28.0 40.6 32.9 62.6 45.2 34.1 45.0 36.9 49.5 50.5 34.4 38.6 81.4 21.4 35.2 30.5 59.8 46.5 29.9 14.0 9.9 8.9 8.7 16.7 12.3 8.0 11.5 9.9 10.3 8.9 10.1 10.7 7.3 10.9 19.6 7.0 12.1 8.7 11.2 12.2 15.0 19.4 12.6 17.2 17.8 17.8 18.9 12.9 16.0 12.5 59.6 48.1 58.8 9.8 37.9 112.3 119.5 109.0 43.3 40.8 37.9 33.0 108.1 25.8 97.7 46.0 25.0 88.3 47.9 29.7 70.5 80.7 158.1 99.1 62.3 73.8 32.9 67.3 21.0 78.7 88.8 64.0 33.1 125.3 50.6 39.9 41.0 84.1 56.0 92.5 22.0 28.6 65.1 44.7 90.6 197.0 46.3 50.6 48.0 10.3 59.8 58.6 37.0 14.6 15.0 84.9 22.7 44.0 58.2 93.4 26.0 77.2 68.1 44.6 26.3 78.6 146.8 126.2 108.0 52.9 94.8 123.0 53.8 53.8 34.1 123.2 PSMD14 "pad1, POH1, Rpn11" ENSG00000115233 "Proteasome 26S subunit, non-ATPase 14" O00487 2 161308425-161411717 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002114, HPA003828" Approved Supported Nucleoplasm NA NA 26000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA002114: AB_1855850, HPA003828: AB_2667057" "unprognostic (3.50e-3)" "unprognostic (1.48e-1)" "unprognostic (9.61e-2)" "unprognostic (6.63e-2)" "unprognostic (2.57e-1)" "unprognostic (7.61e-3)" "prognostic unfavorable (2.66e-8)" "unprognostic (3.11e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-3)" "unprognostic (9.84e-3)" "unprognostic (3.02e-1)" "prognostic unfavorable (3.10e-6)" "unprognostic (2.86e-2)" "unprognostic (4.70e-2)" "unprognostic (3.54e-1)" "unprognostic (1.66e-1)" 35.2 38.3 38.6 39.7 40.0 38.8 36.4 42.5 47.5 26.2 36.7 35.2 29.1 24.7 30.1 40.7 27.3 23.7 44.6 40.7 43.3 44.4 48.4 26.9 37.8 42.1 41.7 14.5 25.6 51.1 21.4 42.0 43.7 31.0 41.0 37.9 20.8 29.9 98.0 33.2 26.4 39.6 43.8 22.9 27.2 38.7 41.1 49.7 34.7 76.0 52.0 42.5 19.6 46.6 170.3 145.8 158.8 140.8 113.9 97.0 194.2 173.6 168.2 246.1 198.6 216.2 140.2 200.2 258.0 128.7 144.3 126.5 176.8 185.6 244.6 210.3 133.1 200.8 110.8 245.9 139.7 196.7 113.8 74.4 138.8 277.4 256.8 94.0 185.5 117.1 222.1 139.6 207.7 164.1 145.0 148.0 220.5 124.3 218.2 123.6 154.4 196.0 218.6 145.0 138.4 101.3 117.8 131.7 167.5 131.4 90.2 124.3 147.2 162.7 152.4 111.6 193.8 82.5 242.7 186.7 174.1 129.6 182.2 47.4 48.2 25.2 65.3 69.6 68.7 64.2 69.4 71.0 75.4 57.4 55.4 66.5 4.9 70.2 56.2 74.5 83.7 73.3 38.6 40.0 42.5 47.5 40.7 43.3 42.1 41.7 43.7 43.8 41.1 46.6 40.1 51.3 38.2 35.3 49.4 49.5 48.1 146.8 25.0 43.7 40.2 36.2 89.8 52.9 80.3 23.9 18.8 159.5 60.4 47.7 90.1 124.3 82.5 52.4 51.8 49.9 52.5 56.2 64.0 118.3 154.6 48.1 29.6 58.4 51.2 59.0 31.8 125.3 104.7 47.1 56.1 53.5 118.0 41.1 40.0 36.0 27.7 46.1 48.0 25.3 61.1 87.7 44.3 50.3 64.6 155.0 48.0 34.3 60.2 57.0 36.5 106.1 55.4 60.6 32.9 36.6 64.5 137.0 77.7 34.3 56.0 220.3 47.8 63.6 64.5 50.8 PSMD4 "AF, AF-1, Rpn10, S5A" ENSG00000159352 "Proteasome 26S subunit, non-ATPase 4" P55036 1 151254709-151267479 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038807, HPA039252, CAB047300" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 69000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB047300: , HPA038807: AB_2676217, HPA039252: AB_10673418" "unprognostic (3.83e-2)" "unprognostic (7.89e-2)" "unprognostic (6.86e-3)" "unprognostic (1.70e-1)" "unprognostic (2.63e-1)" "unprognostic (2.89e-2)" "unprognostic (1.79e-3)" "unprognostic (2.16e-1)" "unprognostic (2.81e-1)" "unprognostic (2.61e-2)" "unprognostic (7.57e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (6.66e-10)" "unprognostic (9.80e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (3.91e-1)" 108.8 118.0 198.8 77.8 203.8 89.4 97.9 203.0 288.1 88.7 195.2 136.9 68.9 99.5 114.3 115.5 91.0 58.2 191.2 202.8 205.8 110.2 170.5 81.7 95.7 208.5 215.3 85.8 114.0 91.6 79.4 91.1 209.3 91.3 82.1 64.5 83.9 86.4 404.1 103.3 91.3 91.0 204.2 109.6 115.4 152.0 203.7 114.3 76.7 188.0 114.0 118.6 88.2 203.4 251.4 294.8 213.4 175.2 227.4 167.0 231.9 166.0 202.1 258.6 205.1 388.3 278.2 202.2 396.2 235.4 178.7 255.4 277.1 250.6 219.6 331.9 236.6 197.8 256.2 396.6 250.8 234.7 220.5 182.5 204.2 296.3 271.4 193.3 229.5 222.4 313.6 247.9 220.2 723.5 217.4 276.7 406.0 384.3 293.4 181.6 207.7 364.7 252.7 210.6 166.7 283.8 184.5 266.3 222.7 313.0 278.9 452.3 203.4 128.1 201.2 159.2 288.2 295.1 397.7 430.3 212.6 218.1 238.7 439.4 439.0 713.9 247.3 478.1 281.2 399.0 287.4 274.4 398.4 426.1 261.0 258.1 580.2 351.2 502.3 240.3 476.6 651.0 198.8 203.8 203.0 288.1 202.8 205.8 208.5 215.3 209.3 204.2 203.7 203.4 90.1 57.7 62.9 15.7 78.5 88.6 111.9 249.0 58.1 50.9 60.9 69.3 245.2 82.9 125.0 60.7 27.1 328.6 74.0 104.1 168.3 177.3 279.1 91.5 63.0 95.8 84.2 107.3 25.3 186.9 234.1 88.5 46.9 59.1 83.6 88.8 83.2 116.0 184.5 33.7 24.2 94.1 156.6 104.0 98.0 243.2 105.3 90.3 104.9 11.2 256.6 91.9 115.4 16.1 23.2 172.2 129.1 98.6 67.0 121.4 168.6 206.6 148.3 54.6 118.3 79.0 221.1 234.8 83.5 66.7 86.5 414.6 77.7 105.6 114.5 107.2 PTCD2 FLJ12598 ENSG00000049883 "Pentatricopeptide repeat domain 2" Q8WV60 5 72320367-72368395 "Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043686 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043686: AB_10962485" "unprognostic (1.59e-2)" "unprognostic (2.64e-1)" "unprognostic (2.30e-3)" "unprognostic (2.38e-2)" "unprognostic (2.19e-1)" "unprognostic (8.23e-2)" "unprognostic (1.73e-1)" "unprognostic (8.91e-2)" "unprognostic (6.62e-2)" "unprognostic (7.60e-4)" "unprognostic (7.68e-3)" "unprognostic (1.93e-1)" "unprognostic (7.26e-2)" "unprognostic (9.91e-3)" "unprognostic (3.68e-2)" "unprognostic (9.24e-4)" "unprognostic (2.53e-1)" 4.0 4.7 3.9 1.7 4.0 1.3 3.1 4.1 4.7 2.5 6.2 2.5 1.0 2.3 3.6 2.9 2.7 2.0 7.4 3.9 3.9 3.8 4.6 1.5 2.3 4.0 4.2 3.1 1.8 4.8 3.1 3.2 4.5 2.4 2.5 4.6 2.1 2.6 8.7 2.9 1.8 2.8 3.6 2.0 2.2 2.1 4.1 2.7 4.0 13.8 2.6 3.1 2.6 4.8 5.1 7.7 4.9 6.0 9.9 8.7 6.2 7.5 4.9 7.4 6.2 6.1 6.0 7.9 10.3 5.0 14.2 3.8 9.5 14.6 7.9 3.6 5.1 5.5 9.7 3.5 14.7 2.7 1.5 9.7 7.6 9.7 20.3 8.4 5.4 11.2 6.5 4.9 11.2 4.7 6.6 6.3 4.6 2.3 6.5 4.6 5.7 17.6 8.6 3.5 5.2 3.5 6.6 4.2 6.8 5.6 11.7 5.5 4.0 3.8 4.3 5.6 7.6 6.3 8.2 5.0 7.3 8.1 7.6 0.0 0.9 0.2 1.1 1.2 1.3 1.1 1.2 1.0 1.9 1.6 1.5 1.9 0.3 3.1 1.4 1.6 2.1 0.6 3.9 4.0 4.1 4.7 3.9 3.9 4.0 4.2 4.5 3.6 4.1 4.8 2.9 3.2 4.8 16.0 5.5 0.8 3.1 3.1 3.4 5.2 3.5 2.7 13.5 4.3 1.8 3.7 25.0 14.9 7.8 1.2 11.7 4.2 0.3 3.0 7.4 4.6 1.2 3.8 10.7 2.3 7.3 5.4 1.5 2.8 1.3 8.6 3.3 8.4 4.6 5.0 10.2 2.1 6.1 4.4 1.3 1.4 4.1 3.3 0.0 8.4 4.8 8.3 7.2 12.1 19.2 2.7 1.1 4.9 1.5 1.5 3.2 5.5 3.1 14.8 0.0 5.3 4.9 4.9 8.6 4.2 0.1 7.1 4.4 9.9 3.6 1.7 PTCD3 "DKFZp666K071, FLJ20758" ENSG00000132300 "Pentatricopeptide repeat domain 3" Q96EY7 2 86106223-86142157 "Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041154, HPA041382" Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA041154: AB_10795488, HPA041382: AB_10795695" "unprognostic (1.16e-2)" "unprognostic (4.47e-2)" "unprognostic (1.37e-2)" "unprognostic (9.30e-3)" "unprognostic (2.40e-2)" "unprognostic (2.54e-1)" "unprognostic (4.92e-3)" "unprognostic (2.06e-2)" "unprognostic (4.78e-2)" "unprognostic (3.78e-1)" "unprognostic (7.42e-3)" "unprognostic (5.49e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.77e-4)" "unprognostic (3.69e-1)" "unprognostic (7.79e-2)" "prognostic favorable (6.86e-4)" 10.0 15.8 13.1 7.6 14.2 14.7 9.9 15.2 15.9 11.6 16.3 12.6 10.1 11.7 10.2 10.7 11.7 6.4 26.2 13.3 14.5 12.4 16.5 9.6 11.8 13.6 14.0 15.1 10.7 13.1 14.8 9.2 14.7 10.4 13.5 13.2 9.8 7.5 32.8 10.3 11.9 9.0 13.7 12.0 11.8 16.6 13.5 10.5 12.0 36.3 11.1 10.3 10.7 16.7 16.2 37.6 22.0 18.5 16.1 16.6 26.2 32.6 13.8 18.0 18.0 69.9 15.1 39.7 11.8 17.1 18.6 28.9 44.7 17.7 22.9 17.8 37.0 31.8 23.0 59.2 16.3 26.0 23.1 19.8 12.8 13.7 24.4 18.8 15.7 28.6 33.5 14.8 16.0 15.0 21.7 31.0 20.2 31.5 23.9 28.8 30.9 30.6 24.6 31.7 23.9 14.7 15.2 25.0 30.4 20.6 13.2 15.7 11.3 14.2 15.1 14.6 19.2 33.7 47.6 31.6 13.8 29.4 11.1 4.4 9.6 7.6 12.4 7.0 14.6 15.3 11.2 13.2 10.6 16.4 15.1 11.3 0.3 14.3 14.1 10.7 13.9 8.8 13.1 14.2 15.2 15.9 13.3 14.5 13.6 14.0 14.7 13.7 13.5 16.7 17.1 57.7 33.5 50.3 31.0 26.0 26.3 27.7 34.7 61.7 19.2 16.8 105.7 18.6 37.4 23.9 66.7 53.0 30.6 21.7 25.4 18.8 34.8 27.5 33.3 23.5 31.1 39.5 52.9 11.9 27.0 30.5 30.1 24.2 33.6 47.5 21.4 41.7 21.7 37.0 53.1 25.3 20.3 19.6 13.3 22.4 27.1 17.7 8.8 21.5 22.7 49.8 28.8 48.7 53.4 15.0 19.2 19.5 26.4 23.7 23.2 30.1 26.2 65.3 13.1 36.3 21.3 98.3 62.4 28.7 24.7 36.7 31.8 47.9 38.5 20.4 PTGES2 "C9orf15, FLJ14038" ENSG00000148334 "Prostaglandin E synthase 2" Q9H7Z7 9 128120693-128128462 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 700.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020631, HPA020733" Approved Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA020631: AB_1855887, HPA020733: AB_2670508" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (5.13e-3)" "unprognostic (2.56e-1)" "unprognostic (1.57e-1)" "unprognostic (7.10e-2)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.83e-7)" "unprognostic (2.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" 18.1 49.8 31.6 15.6 33.9 6.5 16.0 29.1 45.8 18.1 32.4 30.6 27.5 21.6 4.0 35.3 17.6 11.4 95.0 35.6 33.0 36.4 37.7 14.8 17.6 31.5 31.5 16.1 37.6 35.2 41.4 9.7 32.1 24.6 9.2 10.0 26.1 16.8 117.9 20.9 23.8 7.5 27.3 21.1 29.6 14.5 31.5 11.9 23.5 78.7 9.7 22.3 22.0 31.7 46.1 114.0 15.5 54.4 13.5 12.8 47.9 30.7 20.6 48.6 24.9 86.9 75.6 43.5 45.7 15.9 36.9 108.8 22.5 47.1 6.5 28.3 62.3 21.0 92.7 79.5 41.0 42.1 39.5 18.6 32.3 39.5 26.9 14.2 31.6 47.8 50.2 26.4 16.7 130.0 56.9 75.6 42.7 58.7 113.9 39.6 26.5 111.6 32.8 33.1 69.1 45.6 47.3 86.3 34.2 6.7 78.7 23.5 34.0 46.3 50.2 62.8 63.1 48.9 25.5 38.3 39.1 33.2 44.5 1.4 3.3 0.7 3.1 3.7 3.8 3.8 2.2 3.5 4.3 2.7 2.4 3.0 0.6 2.7 1.8 5.8 3.1 1.9 31.6 33.9 29.1 45.8 35.6 33.0 31.5 31.5 32.1 27.3 31.5 31.7 18.8 16.0 6.4 10.4 32.0 22.9 38.1 32.7 25.0 37.8 34.2 36.3 700.2 51.5 25.9 23.9 20.9 82.1 30.8 86.1 146.8 74.6 2.1 12.7 20.9 29.4 45.1 13.2 15.5 51.8 62.1 32.7 46.4 17.3 14.7 31.9 13.9 37.8 57.6 37.0 15.8 62.2 46.8 25.3 43.6 4.8 30.7 30.8 56.9 3.7 105.7 21.9 38.1 12.1 7.2 57.6 60.4 21.8 45.4 68.0 93.4 99.3 9.3 44.8 19.7 17.8 37.2 3.6 45.6 48.3 24.6 66.6 25.6 84.1 105.5 52.9 PTGR2 "FLJ39091, ZADH1" ENSG00000140043 "Prostaglandin reductase 2" Q8N8N7 14 73851844-73886827 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 41.9" HPA001125 Approved Approved Vesicles NA NA 36000 "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA001125: AB_2666207" "unprognostic (3.82e-2)" "unprognostic (2.79e-2)" "unprognostic (6.05e-2)" "unprognostic (3.26e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (8.10e-3)" "unprognostic (6.99e-3)" "unprognostic (5.96e-1)" "prognostic favorable (4.55e-12)" "unprognostic (4.42e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" 6.9 12.2 10.4 2.8 11.5 0.9 9.1 11.1 12.1 4.8 11.6 7.2 12.1 4.6 17.2 5.0 12.0 5.2 27.1 9.9 11.7 18.9 19.1 5.6 3.1 11.8 11.9 7.4 5.3 10.6 7.6 2.4 12.1 9.1 5.7 10.7 6.7 5.4 32.8 6.9 8.9 2.6 11.3 3.4 6.2 6.2 10.6 3.0 12.6 32.1 2.6 4.2 4.1 13.9 8.9 11.9 9.6 4.7 7.6 16.3 7.6 3.0 4.1 3.6 5.6 6.8 21.2 0.9 6.8 3.0 8.4 8.8 8.7 6.5 6.6 6.7 4.1 6.2 5.5 3.0 3.8 2.3 2.2 7.7 15.1 5.5 4.4 7.8 1.8 6.1 8.3 1.8 8.2 12.7 6.2 5.9 10.7 11.9 11.6 7.6 3.7 1.5 19.7 8.6 12.7 11.0 7.7 8.1 9.8 9.1 41.9 3.7 2.7 5.3 10.0 3.9 6.6 10.2 4.7 2.8 8.3 5.5 7.2 6.7 1.1 0.9 0.6 0.4 0.6 1.0 1.1 0.5 1.3 1.0 1.8 1.5 0.8 1.3 1.2 1.5 1.1 1.0 10.4 11.5 11.1 12.1 9.9 11.7 11.8 11.9 12.1 11.3 10.6 13.9 4.5 19.2 13.0 10.7 2.9 6.8 12.8 16.7 6.2 8.9 8.4 5.5 43.2 8.6 12.9 18.4 14.6 6.3 2.0 8.6 25.4 11.7 2.4 21.5 5.8 5.2 4.8 4.2 8.0 8.7 2.5 6.1 5.1 7.3 3.8 9.3 3.3 14.3 7.4 33.7 10.3 10.0 10.2 5.5 3.1 2.0 7.2 4.3 8.8 5.6 4.0 22.3 6.2 7.1 20.4 8.7 11.1 6.8 2.9 7.2 24.8 18.4 31.6 20.8 6.6 9.9 6.1 42.1 18.8 3.5 6.7 4.0 2.9 17.3 11.7 7.7 PTPA "PPP2R4, PR53" ENSG00000119383 "Protein phosphatase 2 phosphatase activator" Q15257 9 129110950-129148946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 51.9;Collecting duct cells: 53.3;Cytotrophoblasts: 49.5;Distal tubular cells: 54.8;Ductal cells: 70.3;Exocrine glandular cells: 62.3;Hofbauer cells: 53.9;Pancreatic endocrine cells: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005695, CAB022068, CAB035999" Approved Enhanced Nucleoplasm,Cytosol NA NA 4300000 "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "CAB022068: , CAB035999: , HPA005695: AB_1855658" "unprognostic (4.97e-2)" "unprognostic (1.70e-2)" "unprognostic (1.13e-2)" "prognostic favorable (6.50e-5)" "unprognostic (1.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.65e-2)" "unprognostic (6.44e-3)" "unprognostic (2.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" 47.2 118.0 157.8 56.2 154.0 52.9 60.9 136.2 185.0 73.5 124.6 105.2 49.6 87.4 55.8 116.8 77.3 49.3 176.7 158.5 141.6 125.5 154.2 72.6 49.9 151.3 148.8 63.8 70.4 146.7 73.1 49.8 147.6 119.0 51.3 43.4 97.1 86.8 340.8 73.7 57.1 92.1 143.2 82.8 83.5 124.5 162.7 59.1 75.3 206.2 54.9 71.1 62.2 148.5 108.9 183.9 111.0 219.9 74.4 94.5 118.3 115.5 120.2 144.8 100.1 103.4 135.4 113.9 83.3 187.3 173.1 184.1 110.9 138.2 100.6 198.6 68.1 64.6 193.6 101.7 229.1 113.1 147.2 114.6 133.1 109.8 101.8 230.9 146.5 120.3 102.0 124.7 117.1 293.8 103.0 76.6 186.8 301.0 193.0 108.3 93.7 216.2 159.0 119.8 120.6 86.9 220.4 237.3 147.3 99.4 253.4 55.0 101.7 127.6 113.8 129.9 165.2 114.9 284.1 96.8 153.2 79.1 180.7 7.6 19.2 9.8 20.8 18.4 19.9 10.8 15.8 18.5 23.0 13.4 13.8 13.9 6.1 20.4 18.3 16.4 16.9 20.4 157.8 154.0 136.2 185.0 158.5 141.6 151.3 148.8 147.6 143.2 162.7 148.5 19.8 3.2 8.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 51.9 38.6 0.0 0.0 3.1 53.3 0.0 49.5 9.2 0.0 54.8 70.3 0.0 33.7 21.8 19.0 0.0 0.0 0.0 62.3 44.2 12.2 0.0 32.9 8.8 24.8 0.0 0.0 53.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 21.7 0.0 0.0 0.0 0.0 61.8 0.0 0.0 0.9 0.0 0.0 41.9 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 37.9 4.0 31.8 0.0 0.0 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 142.0;Astrocytes: 188.1;Inhibitory neurons: 751.6;Microglial cells: 263.3;Oligodendrocyte precursor cells: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Cell line enhanced" "Detected in many" "ASC diff: 98.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA Yes 130000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.59e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favorable (1.07e-4)" 53.1 24.1 18.9 11.9 37.6 1.2 41.8 13.0 27.7 18.4 44.2 25.3 8.7 24.2 11.9 14.2 23.3 32.4 61.2 12.7 38.7 29.5 11.8 38.9 15.5 21.7 53.0 26.4 13.2 23.4 16.1 33.2 34.3 16.7 11.5 19.3 10.9 36.0 52.5 12.3 15.1 24.8 5.8 23.1 18.4 22.8 47.6 16.7 54.8 63.4 11.9 23.9 12.2 14.4 4.6 33.4 15.7 0.2 98.0 67.4 38.7 41.1 35.6 26.9 39.5 30.9 7.1 0.0 39.0 49.1 0.5 0.3 0.2 14.3 36.9 0.5 7.2 0.0 22.2 15.2 27.9 0.0 0.4 77.1 29.3 14.9 42.1 51.1 27.2 0.0 0.0 13.8 21.8 0.7 13.7 0.3 2.6 9.9 7.3 0.5 13.5 63.9 64.9 57.6 1.4 8.6 1.1 0.2 34.6 24.9 0.2 0.0 28.2 54.9 34.6 26.4 7.2 1.1 0.4 0.3 46.8 0.2 10.4 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.8 4.7 0.0 0.0 1.0 2.0 0.0 0.0 0.0 1.8 0.7 1.1 18.9 37.6 13.0 27.7 12.7 38.7 21.7 53.0 34.3 5.8 47.6 14.4 142.0 44.8 36.0 188.1 1.1 6.0 7.3 3.0 2.8 28.3 2.5 3.2 26.7 14.3 7.1 5.5 2.1 11.4 5.4 0.9 1.9 17.6 25.9 28.9 15.6 68.9 1.8 0.4 70.1 8.3 3.4 14.0 8.2 59.6 2.5 13.0 47.2 25.3 9.9 0.0 751.6 1.4 0.0 8.0 5.7 42.0 2.8 5.1 30.2 263.3 0.6 2.9 3.1 224.7 50.3 14.3 1.2 5.3 2.3 8.3 3.0 13.3 15.6 2.2 6.6 7.4 9.9 8.6 9.9 0.9 2.8 12.6 5.7 3.7 0.8 8.6 PTRHD1 "C2orf79, LOC391356" ENSG00000184924 "Peptidyl-tRNA hydrolase domain containing 1" Q6GMV3 2 24789728-24793391 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019951 Approved Approved Nucleoplasm NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA019951: AB_1853109" "unprognostic (1.28e-2)" "unprognostic (5.79e-2)" "unprognostic (6.34e-2)" "unprognostic (1.34e-2)" "unprognostic (2.61e-2)" "unprognostic (3.99e-1)" "unprognostic (8.84e-3)" "unprognostic (1.26e-1)" "unprognostic (3.69e-1)" "unprognostic (8.31e-3)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (2.93e-1)" "unprognostic (1.55e-1)" "unprognostic (1.51e-1)" "unprognostic (5.76e-2)" 10.6 26.0 11.7 4.3 11.8 16.1 11.0 12.2 17.5 8.7 13.7 12.8 10.6 7.2 3.5 17.6 6.4 4.2 16.4 12.5 12.6 14.9 14.9 10.2 8.4 12.4 11.9 10.2 13.7 3.6 10.8 6.4 12.6 10.6 5.8 3.0 15.1 4.0 23.9 14.8 11.9 3.3 12.5 11.2 12.3 9.1 12.8 7.1 14.5 8.5 6.2 9.4 10.3 13.0 18.2 40.2 12.7 5.5 6.9 15.2 22.1 12.2 11.3 15.4 9.9 39.7 15.9 14.2 5.2 12.7 10.3 11.7 10.4 11.1 5.1 20.1 70.0 25.7 18.2 43.2 14.2 21.8 23.5 14.6 8.9 7.1 7.9 12.3 14.4 12.8 26.4 11.2 11.4 36.6 17.7 39.0 26.8 10.6 23.7 14.9 38.9 23.9 18.1 31.2 19.9 30.9 13.6 18.1 16.4 5.9 17.7 15.9 24.2 13.6 21.4 6.7 11.2 8.7 28.1 15.4 12.4 13.3 9.3 34.8 90.6 20.7 52.6 66.9 26.8 96.4 51.4 46.2 144.5 81.2 46.6 54.8 10.4 52.8 50.1 149.0 84.4 97.0 11.7 11.8 12.2 17.5 12.5 12.6 12.4 11.9 12.6 12.5 12.8 13.0 27.8 51.3 61.5 1.0 65.0 119.8 79.4 123.3 72.3 10.5 171.4 239.4 81.0 60.1 83.8 66.2 6.2 200.0 87.9 127.0 115.4 91.0 130.9 53.5 37.5 46.9 88.1 68.1 1.9 142.0 153.7 57.4 50.4 48.8 41.2 121.1 62.4 101.5 134.5 1.7 2.2 158.2 79.3 112.5 154.3 157.1 47.2 79.9 67.6 3.7 154.6 78.7 65.9 1.0 2.3 124.2 128.8 39.9 46.6 74.3 120.9 199.2 107.1 12.2 72.3 34.5 56.0 135.6 78.6 133.6 141.8 167.7 52.5 110.4 162.2 125.3 PYCR2 P5CR2 ENSG00000143811 "Pyrroline-5-carboxylate reductase 2" Q96C36 1 225919877-225924340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA056873 Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Mitochondria "HPA056873: AB_2683263" "unprognostic (1.11e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (5.02e-5)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (4.20e-3)" "unprognostic (1.56e-2)" "unprognostic (6.89e-2)" "unprognostic (1.12e-1)" "unprognostic (9.07e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (9.69e-2)" "unprognostic (2.61e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" 38.0 71.7 53.2 35.8 62.4 47.3 35.8 68.1 54.2 46.4 51.8 39.6 22.3 48.5 26.4 32.3 44.7 22.4 62.3 50.4 61.3 40.2 40.3 38.2 47.2 69.0 61.2 47.9 47.2 42.0 57.0 28.5 66.0 39.6 18.3 34.0 39.6 40.9 66.8 28.3 34.4 25.7 68.6 49.5 38.9 34.4 59.2 43.9 30.0 49.1 33.9 50.3 33.3 72.5 72.6 59.6 35.0 59.1 38.8 40.0 73.2 74.8 46.3 49.7 44.1 77.2 58.3 126.1 156.6 55.0 39.1 81.6 50.5 58.6 28.3 154.6 107.5 120.6 60.2 81.5 59.8 107.9 189.1 38.8 72.3 56.1 64.1 44.1 47.8 103.7 178.4 81.6 50.9 60.5 135.8 120.9 196.0 112.8 80.4 120.2 79.0 263.6 65.2 58.3 44.0 56.7 62.4 48.7 161.0 27.9 62.3 202.0 40.3 38.4 46.5 82.9 104.4 129.9 156.2 127.4 60.7 80.6 109.3 38.4 19.6 39.6 45.5 29.2 47.8 34.4 43.8 42.4 31.3 41.9 74.9 62.4 13.3 67.9 26.3 59.2 44.0 45.1 53.2 62.4 68.1 54.2 50.4 61.3 69.0 61.2 66.0 68.6 59.2 72.5 28.0 19.2 22.8 11.4 31.6 14.8 64.6 53.4 8.0 15.6 24.3 21.2 47.6 20.0 24.8 35.0 14.6 90.6 39.1 12.9 49.0 50.0 8.2 92.8 25.6 26.7 26.5 58.7 4.6 34.0 46.3 23.7 10.2 31.8 38.7 74.9 21.0 16.6 40.0 13.5 5.8 17.8 57.0 20.4 19.8 8.8 38.2 31.5 33.8 8.4 46.4 46.9 46.4 5.5 29.3 29.1 15.8 37.6 23.1 42.1 18.3 35.8 55.4 42.7 26.3 19.8 24.4 40.1 46.2 9.4 12.8 41.7 34.9 44.9 16.1 40.4 RAB21 KIAA0118 ENSG00000080371 "RAB21, member RAS oncogene family" Q9UL25 12 71754863-71800286 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 497.9;Late spermatids: 807.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016988, CAB037048" Approved NA NA 13000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "CAB037048: AB_1841130, HPA016988: AB_1855998" "unprognostic (4.38e-2)" "unprognostic (1.49e-2)" "unprognostic (8.57e-2)" "unprognostic (3.03e-1)" "unprognostic (6.28e-2)" "unprognostic (1.56e-1)" "unprognostic (1.44e-1)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" "unprognostic (1.26e-1)" "unprognostic (2.43e-2)" "unprognostic (5.68e-2)" "prognostic favorable (5.39e-8)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.91e-2)" "unprognostic (6.31e-2)" 6.1 7.4 6.1 3.8 7.3 8.0 5.0 6.4 7.5 5.2 4.7 5.3 3.7 4.9 3.9 5.8 4.4 4.5 11.5 5.5 6.5 8.3 6.1 6.5 4.5 7.4 7.2 5.1 3.9 6.5 5.4 5.3 6.9 5.0 3.5 3.5 4.2 4.4 14.2 6.5 4.0 4.3 7.2 4.6 4.3 2.5 6.6 4.6 5.9 7.6 4.2 5.3 5.4 8.2 6.0 4.6 4.7 3.8 7.5 4.8 8.1 8.3 4.9 5.6 3.8 5.6 2.8 9.3 9.5 7.4 3.3 5.1 8.5 5.8 8.8 7.5 3.9 8.6 3.3 6.2 7.7 9.5 5.0 5.6 8.9 6.2 9.6 8.6 3.9 5.1 6.0 5.3 8.6 5.5 7.7 6.3 7.0 3.4 6.9 7.4 5.2 6.7 8.4 8.3 4.7 3.8 10.4 9.8 6.2 5.8 7.7 6.1 6.1 7.3 2.9 11.7 6.2 6.8 7.0 7.1 3.8 5.4 5.3 0.8 0.3 0.5 0.4 0.3 0.4 0.4 0.4 0.3 0.2 0.4 0.4 0.4 1.2 0.4 0.3 0.5 0.3 0.1 6.1 7.3 6.4 7.5 5.5 6.5 7.4 7.2 6.9 7.2 6.6 8.2 93.7 28.9 56.5 17.9 60.7 119.6 78.4 29.6 32.5 45.4 66.1 45.1 179.9 48.6 31.6 47.8 79.2 39.4 96.5 60.4 13.7 22.5 497.9 48.0 56.6 73.1 49.6 21.0 24.9 20.8 38.0 66.6 30.1 109.0 24.1 22.1 48.5 62.3 42.7 52.2 31.9 35.8 20.3 55.7 168.9 807.6 36.1 88.9 55.2 17.8 41.5 41.9 36.0 33.7 47.5 34.2 40.7 41.8 47.8 97.7 44.4 62.5 20.0 37.3 26.3 90.9 81.2 19.2 16.6 56.1 160.1 83.5 59.8 35.5 41.2 117.7 RAB4A "HRES-1/RAB4, RAB4" ENSG00000168118 "RAB4A, member RAS oncogene family" P20338 1 229271062-229305894 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 32.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" "unprognostic (9.21e-2)" "unprognostic (7.58e-2)" "unprognostic (1.81e-2)" "unprognostic (2.09e-1)" "unprognostic (2.09e-2)" "unprognostic (1.21e-1)" "unprognostic (2.83e-1)" "unprognostic (8.53e-2)" "unprognostic (6.41e-2)" "unprognostic (3.85e-2)" "unprognostic (2.99e-2)" "unprognostic (2.47e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-1)" "unprognostic (2.11e-1)" "unprognostic (4.26e-2)" "unprognostic (1.72e-2)" 12.1 12.9 29.7 7.6 27.4 7.2 19.4 27.9 35.7 19.4 24.0 17.9 17.0 12.5 13.4 17.7 15.2 15.0 38.5 24.5 27.3 15.8 30.8 10.9 10.9 25.7 31.4 15.6 24.7 14.3 9.1 11.3 26.0 34.3 19.1 17.3 38.8 20.9 34.2 16.9 13.4 13.4 25.7 7.8 26.7 11.4 34.3 12.4 19.8 35.0 11.8 15.4 13.9 27.7 10.3 13.8 22.6 15.7 31.7 35.1 18.9 15.4 18.3 9.2 8.8 25.6 16.8 0.0 25.1 20.7 7.7 11.1 15.2 21.6 12.9 13.1 30.7 13.9 11.8 40.2 20.5 28.2 10.9 27.1 30.4 6.4 8.9 27.1 20.8 14.9 14.8 0.0 16.1 13.3 14.4 18.8 20.4 63.1 19.1 4.6 3.6 7.2 48.6 24.4 19.4 25.3 12.7 19.1 27.6 11.9 18.1 49.5 14.6 0.0 7.3 14.6 21.4 11.9 11.8 0.1 6.4 23.9 21.8 21.4 5.5 32.7 2.2 6.5 2.2 3.0 2.9 2.9 6.8 3.7 1.8 2.4 1.2 2.2 4.2 3.8 3.7 3.5 29.7 27.4 27.9 35.7 24.5 27.3 25.7 31.4 26.0 25.7 34.3 27.7 43.9 16.0 22.1 37.5 48.4 137.0 155.0 135.3 153.1 29.4 82.3 88.8 91.7 154.4 60.5 44.1 47.9 77.7 61.1 81.9 113.5 89.0 158.0 81.7 45.7 45.3 48.6 52.0 23.6 115.4 88.5 47.2 68.3 47.1 24.8 41.5 52.5 119.2 67.8 30.3 24.2 82.6 79.3 78.4 96.3 169.4 46.6 76.0 64.0 16.9 80.4 33.2 50.4 23.6 38.0 84.9 105.7 83.8 47.6 145.2 73.0 128.1 63.2 58.4 46.0 41.6 46.0 92.6 35.2 83.8 122.6 58.0 50.5 39.5 110.5 161.9 RAB6A RAB6 ENSG00000175582 "RAB6A, member RAS oncogene family" P20340 11 73675638-73761137 "Predicted intracellular proteins" "ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009936, HPA059131" Approved Approved "Golgi apparatus" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "CAB009936: AB_2175466, HPA059131: AB_2683916" "unprognostic (2.84e-1)" "unprognostic (7.18e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (8.18e-5)" "unprognostic (1.79e-1)" "unprognostic (9.44e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (8.67e-3)" "unprognostic (1.16e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (9.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-1)" "unprognostic (2.77e-1)" "unprognostic (4.93e-2)" "unprognostic (2.36e-1)" 71.2 69.8 87.7 53.0 96.5 38.4 50.6 85.4 112.8 64.4 79.3 66.2 71.6 66.9 53.0 100.2 54.0 55.6 99.5 101.8 100.9 75.1 85.3 68.5 45.7 106.0 90.1 64.5 49.0 67.5 36.4 91.4 112.9 64.0 70.6 56.1 47.8 64.9 107.5 55.0 83.4 79.8 80.0 56.9 54.9 36.1 97.4 54.2 98.7 101.7 60.8 78.9 62.4 93.4 86.2 66.3 105.8 68.5 135.9 154.3 141.7 130.4 124.6 111.1 100.8 131.5 146.4 73.2 136.6 174.0 94.9 94.6 68.4 135.3 142.5 84.6 25.6 118.2 68.6 110.9 114.2 78.1 113.1 114.7 246.8 113.5 165.0 124.4 135.9 75.7 71.3 111.5 133.3 99.6 85.7 54.7 42.2 192.0 62.3 64.8 193.9 132.5 135.2 146.6 83.0 70.5 136.1 136.7 290.9 104.7 107.2 71.0 165.0 113.3 56.9 193.5 56.6 71.9 89.5 149.5 46.3 63.2 104.6 227.9 81.8 133.2 84.2 87.6 76.2 56.1 70.3 75.5 62.9 50.7 52.0 61.8 61.9 78.6 88.6 33.7 86.3 111.1 87.7 96.5 85.4 112.8 101.8 100.9 106.0 90.1 112.9 80.0 97.4 93.4 66.3 32.1 51.0 79.7 59.2 83.5 49.4 57.2 88.2 53.9 45.8 30.4 64.2 35.8 42.7 68.0 87.6 109.9 55.3 85.2 43.0 66.0 8.8 51.5 41.3 78.7 52.0 47.5 133.6 49.5 162.3 60.5 52.5 51.2 48.8 83.7 72.5 63.7 65.7 40.4 119.0 61.8 75.3 58.4 85.7 9.5 52.8 58.3 72.9 49.6 74.2 47.7 52.5 130.7 109.4 79.0 61.7 61.7 86.3 57.8 102.7 54.1 47.2 54.2 26.3 47.4 65.5 74.2 53.4 106.5 112.7 173.6 63.8 45.0 50.8 69.8 RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004549: AB_628192, HPA019669: AB_1856019, HPA024235: AB_1856020, HPA024691: AB_1856021" "unprognostic (3.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-1)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.25e-2)" "unprognostic (3.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (7.73e-2)" "prognostic favorable (6.43e-4)" "unprognostic (1.14e-1)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (9.00e-3)" 30.1 23.6 39.1 23.2 45.8 17.1 43.9 41.0 49.3 22.2 32.0 21.1 16.5 26.8 25.1 18.5 16.7 21.7 32.4 37.9 46.7 23.5 32.8 19.5 33.5 43.1 44.8 21.7 18.0 48.0 19.7 30.8 44.2 31.0 20.7 58.2 22.7 21.8 68.5 16.3 18.9 27.5 43.5 28.3 24.0 18.8 43.7 37.3 25.8 52.4 40.3 23.1 15.2 50.7 45.5 57.5 59.6 33.3 60.9 60.5 31.2 58.3 44.5 61.8 58.5 51.4 19.7 98.3 46.0 61.2 35.0 35.9 87.8 50.0 86.4 60.7 75.0 60.9 73.1 39.4 56.4 41.3 37.9 47.2 33.3 59.6 76.5 37.7 54.4 49.9 52.3 48.3 54.2 32.7 66.1 30.4 26.8 25.8 24.9 61.2 70.8 32.4 30.6 43.1 25.3 39.4 52.4 52.8 49.5 52.3 95.9 17.2 46.9 53.1 24.2 52.6 69.6 26.9 31.0 52.4 41.2 62.3 37.5 14.9 21.1 22.4 25.0 22.7 21.9 80.4 19.5 24.0 22.6 96.7 24.6 21.5 30.4 22.6 50.9 35.0 20.0 16.6 39.1 45.8 41.0 49.3 37.9 46.7 43.1 44.8 44.2 43.5 43.7 50.7 36.4 35.3 45.1 57.5 53.8 24.0 30.1 17.0 25.6 51.5 87.3 46.0 91.1 14.3 32.9 18.4 39.6 39.7 47.2 18.6 41.1 30.4 7.6 19.8 55.5 37.9 16.3 58.3 123.7 23.8 35.0 38.5 23.4 25.3 12.6 47.0 34.2 31.7 89.8 35.3 115.9 17.1 30.5 32.1 38.2 6.0 33.8 36.5 30.2 90.9 32.8 89.7 63.8 78.4 114.1 28.3 65.5 28.2 28.2 52.8 16.5 38.1 19.0 52.5 26.3 34.3 47.7 82.2 75.7 25.5 20.3 25.9 34.4 61.2 18.9 33.6 RABGGTB ENSG00000137955 "Rab geranylgeranyltransferase subunit beta" P53611 1 75786197-75795086 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026585, HPA027167, HPA030793" Approved Supported Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA026585: AB_1856026, HPA027167: AB_1856027, HPA030793: " "unprognostic (4.83e-2)" "unprognostic (3.04e-1)" "unprognostic (2.09e-2)" "unprognostic (2.45e-2)" "unprognostic (9.02e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (9.80e-5)" "unprognostic (9.62e-3)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (6.05e-2)" "unprognostic (1.56e-1)" "unprognostic (6.77e-2)" "unprognostic (3.89e-1)" 37.5 56.5 41.0 20.3 44.9 18.3 41.4 44.7 52.8 31.4 40.4 33.9 33.3 24.6 23.6 35.2 28.1 21.4 49.6 40.0 44.8 75.9 67.2 29.0 26.9 44.8 43.6 38.1 67.7 37.5 25.1 31.5 44.8 27.5 29.3 41.2 32.0 23.0 79.7 21.7 24.9 23.0 47.1 29.1 33.9 15.3 43.6 30.6 30.5 84.0 31.3 37.3 30.4 47.9 74.8 40.2 68.6 31.4 85.2 108.8 43.8 99.5 68.2 91.6 70.4 97.3 17.6 68.2 101.3 55.7 146.0 46.0 178.3 77.7 133.8 67.1 48.3 58.0 66.5 158.0 106.6 74.8 32.9 67.5 165.1 84.3 95.4 125.6 75.8 59.7 96.9 65.7 109.9 30.8 61.5 81.4 64.5 53.3 78.0 49.2 114.5 29.9 69.9 41.7 43.5 39.1 24.1 123.6 231.0 58.8 26.1 69.8 77.5 59.6 67.0 142.1 199.5 41.9 127.1 46.4 67.5 60.3 27.0 8.4 7.2 4.7 7.7 11.3 9.3 9.5 7.7 7.2 12.3 5.9 9.4 9.3 1.1 6.3 8.1 11.3 7.7 4.0 41.0 44.9 44.7 52.8 40.0 44.8 44.8 43.6 44.8 47.1 43.6 47.9 35.3 35.3 44.3 12.7 83.3 127.7 59.4 132.6 66.0 22.6 58.5 45.6 71.1 72.9 86.0 27.6 20.9 45.9 65.7 38.6 103.7 44.9 1.6 36.1 42.5 45.8 89.8 41.6 17.1 51.8 60.3 48.6 57.6 40.4 70.5 26.5 41.7 68.6 61.2 32.0 17.8 62.2 75.3 61.3 91.4 4.4 32.3 54.8 58.7 9.4 52.0 36.5 32.0 14.6 21.9 44.1 46.0 33.4 78.8 84.8 58.4 206.5 45.8 22.3 6.6 40.1 59.8 20.1 14.0 73.6 142.9 53.5 60.2 37.5 69.6 88.7 RAD54L2 "ARIP4, KIAA0809, SRISNF2L" ENSG00000164080 "RAD54 like 2" Q9Y4B4 3 51541144-51668667 "Enzymes, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035004, HPA039992, HPA077351" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA035004: AB_10671930, HPA039992: AB_2676789, HPA077351: " "unprognostic (1.46e-2)" "unprognostic (3.67e-2)" "unprognostic (2.61e-1)" "unprognostic (5.01e-2)" "unprognostic (1.15e-1)" "unprognostic (4.38e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-2)" "unprognostic (9.24e-2)" "unprognostic (2.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.71e-5)" "unprognostic (3.72e-2)" "unprognostic (3.19e-1)" "unprognostic (3.30e-2)" "unprognostic (6.63e-2)" 4.6 4.8 5.6 3.7 6.1 6.1 4.6 6.5 5.6 4.8 2.9 5.8 2.5 5.6 4.2 4.0 4.6 2.7 4.4 5.0 5.2 4.0 7.8 4.9 4.2 5.5 5.7 5.3 5.3 3.8 4.5 4.8 5.5 4.4 3.4 7.5 4.5 3.9 7.1 5.5 5.0 4.1 5.3 5.2 5.2 5.0 6.3 6.2 4.6 5.3 5.2 4.8 4.3 6.2 6.6 5.1 12.8 12.7 7.0 5.0 6.7 5.5 7.8 7.4 6.9 9.1 3.8 17.4 1.5 9.7 7.8 5.0 20.5 6.8 9.1 9.2 4.6 14.9 11.5 6.0 6.4 16.8 8.5 5.8 5.4 11.3 10.9 4.6 8.3 14.8 10.3 9.1 5.9 5.1 15.0 7.6 10.2 3.2 5.5 6.9 9.9 2.3 3.8 8.4 5.2 10.0 8.7 8.2 5.7 7.7 5.4 9.9 10.9 7.7 8.9 8.0 10.8 9.8 10.7 16.8 8.3 9.2 10.0 3.1 2.2 2.2 3.3 2.6 3.5 1.8 2.9 2.8 2.3 2.9 1.9 2.3 0.9 3.0 3.5 2.3 2.9 2.2 5.6 6.1 6.5 5.6 5.0 5.2 5.5 5.7 5.5 5.3 6.3 6.2 10.8 9.6 14.4 31.3 11.3 9.2 8.6 6.7 3.4 33.8 8.7 8.0 11.0 15.7 7.8 9.2 31.3 19.3 12.2 7.7 1.9 9.3 7.5 9.5 12.0 15.1 16.3 3.8 54.9 10.4 8.7 9.6 9.2 19.8 18.3 14.2 10.4 21.9 8.9 47.1 54.3 8.1 4.1 9.1 8.4 3.1 15.2 9.4 14.2 26.2 13.2 9.1 30.9 42.7 42.3 13.9 9.7 17.0 11.3 12.4 4.6 4.4 9.5 29.9 13.1 17.1 11.6 43.9 36.4 5.5 8.9 29.7 12.5 10.1 7.9 12.5 RCAN2 "DSCR1L1, ZAKI-4" ENSG00000172348 "Regulator of calcineurin 2" Q14206 6 46220736-46491972 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 199.5;tongue: 180.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 255.4;Excitatory neurons: 261.4;Inhibitory neurons: 254.4;Muller glia cells: 183.1;Oligodendrocytes: 294.6;Smooth muscle cells: 138.4" "Cancer enhanced" "Detected in all" "renal cancer: 25.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "gdT-cell: 1.8;memory CD4 T-cell: 1.1;memory CD8 T-cell: 2.2;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 23 "T-cells: 2.2" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 63.3;HDLM-2: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053880 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA053880: AB_2682290" "unprognostic (2.82e-1)" "unprognostic (7.76e-2)" "unprognostic (4.13e-2)" "unprognostic (1.14e-1)" "unprognostic (5.55e-3)" "unprognostic (4.52e-2)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (2.26e-1)" "unprognostic (4.33e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.37e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (2.11e-2)" 38.1 12.6 35.7 7.7 41.2 0.0 17.1 31.7 106.3 20.3 0.0 20.1 9.8 17.5 51.5 25.9 17.0 35.1 199.5 34.0 65.0 32.4 4.9 16.3 4.1 69.6 76.0 24.0 11.1 85.5 17.5 0.6 68.8 25.3 22.6 61.6 9.6 27.0 73.3 17.2 19.1 14.0 20.6 7.1 36.5 5.7 65.5 4.7 20.1 180.1 7.0 44.0 21.4 62.3 0.0 0.0 1.6 0.0 0.7 0.2 0.1 1.1 15.1 1.1 0.1 0.0 0.0 0.0 0.8 63.3 0.0 0.1 0.0 0.0 0.3 129.7 0.8 0.0 0.0 0.0 1.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.1 5.1 0.0 0.0 0.2 2.7 0.4 0.4 0.4 13.6 0.1 0.2 0.3 4.9 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.8 0.1 0.2 6.8 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.1 2.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 35.7 41.2 31.7 106.3 34.0 65.0 69.6 76.0 68.8 20.6 65.5 62.3 7.6 6.4 5.8 13.7 0.6 6.2 4.6 0.0 0.0 24.8 1.8 1.4 255.4 8.6 0.0 3.7 4.2 0.1 0.8 1.0 70.5 5.5 40.2 0.8 0.4 17.1 25.1 0.0 261.4 2.5 0.0 22.2 1.5 0.8 0.0 0.3 0.4 1.2 0.1 30.3 254.4 1.5 34.6 0.3 8.0 14.2 29.2 0.9 32.0 46.9 0.0 183.1 0.0 76.9 294.6 2.9 0.3 50.4 0.4 3.3 0.0 1.9 0.0 9.7 98.6 16.4 138.4 1.5 1.4 0.5 7.4 0.0 4.0 0.8 0.3 1.4 RDX DFNB24 ENSG00000137710 Radixin P35241 11 109864295-110296712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 155.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, HPA000763, CAB037312" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 38000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Nucleoplasm "CAB037312: AB_261933, HPA000263: AB_1856043, HPA000763: AB_1856042" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (3.85e-1)" "unprognostic (2.74e-2)" "unprognostic (6.93e-2)" "unprognostic (9.82e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.91e-2)" "unprognostic (6.91e-2)" "unprognostic (1.32e-3)" "unprognostic (6.47e-2)" "unprognostic (4.14e-3)" "unprognostic (5.43e-2)" "unprognostic (4.40e-1)" "unprognostic (1.24e-1)" "unprognostic (1.08e-3)" 40.3 155.0 38.0 17.4 57.7 12.0 16.4 50.0 42.7 32.1 32.8 15.2 6.8 28.8 12.9 27.4 19.7 27.2 41.0 35.1 44.7 50.2 68.5 48.8 11.4 52.7 48.2 52.8 52.7 33.2 7.6 35.3 54.3 25.4 11.1 19.2 20.8 26.0 82.1 11.9 7.4 35.0 45.1 26.6 15.0 33.7 47.7 14.3 45.7 59.7 14.6 27.1 10.1 77.6 69.6 35.3 137.3 54.8 78.8 87.4 79.3 85.8 47.6 54.3 59.2 99.7 115.4 0.1 127.4 104.7 84.9 61.5 77.3 80.4 80.5 41.9 44.2 51.5 107.7 74.1 73.6 19.0 33.2 89.7 45.6 68.0 120.1 89.3 149.8 11.1 73.5 29.5 127.0 120.0 11.0 15.6 44.0 4.0 58.4 31.2 96.8 30.1 68.1 33.5 37.2 40.5 148.5 65.9 52.7 102.5 85.0 29.9 92.6 89.5 66.8 43.9 67.4 9.5 17.3 65.9 34.2 11.3 210.9 29.5 14.8 22.0 11.6 12.5 15.5 11.5 10.2 8.8 12.8 8.3 6.8 5.8 2.0 17.6 9.9 10.3 22.0 8.4 38.0 57.7 50.0 42.7 35.1 44.7 52.7 48.2 54.3 45.1 47.7 77.6 248.8 484.0 98.8 53.5 30.0 56.1 51.8 124.6 56.9 85.9 47.4 45.7 159.3 70.1 77.9 75.4 43.8 122.1 21.6 17.7 109.5 128.1 15.5 109.1 117.2 289.2 22.2 104.8 27.1 423.4 189.8 88.4 19.9 135.3 67.2 132.0 319.2 260.1 85.1 101.0 57.6 7.3 61.1 103.2 59.9 43.6 275.2 71.6 72.9 42.2 135.4 77.0 36.0 68.3 229.4 134.3 22.1 266.7 36.1 65.9 0.1 236.9 52.2 94.8 124.9 74.0 143.8 73.9 257.4 52.8 40.5 227.3 29.2 229.9 11.8 45.9 REPIN1 "AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464" ENSG00000214022 "Replication initiator 1" Q9BWE0 7 150368189-150374044 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 7.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 246.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036022 Approved Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA036022: AB_10610417" "unprognostic (2.73e-1)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "unprognostic (7.50e-3)" "unprognostic (5.42e-2)" "unprognostic (7.00e-3)" "unprognostic (1.52e-2)" "unprognostic (6.88e-3)" "unprognostic (6.68e-2)" "unprognostic (6.59e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.40e-2)" "prognostic favorable (5.56e-4)" "prognostic favorable (1.61e-4)" "unprognostic (1.79e-1)" "unprognostic (2.02e-3)" "prognostic favorable (6.41e-4)" 28.7 77.2 45.1 25.2 43.6 44.1 35.1 43.1 46.4 31.7 54.6 68.4 42.2 37.5 31.8 37.4 40.9 14.6 65.3 37.9 40.0 51.5 86.6 31.7 35.7 52.3 46.7 37.3 67.7 35.5 69.7 12.1 45.5 49.2 28.3 23.7 41.7 23.9 134.5 31.8 56.5 15.4 41.1 56.2 53.1 18.2 49.5 41.0 45.0 66.2 24.8 42.5 25.0 42.1 59.4 71.3 66.1 81.5 15.8 11.3 40.2 28.7 35.2 27.6 23.8 55.5 37.6 65.5 70.9 20.6 48.0 43.4 36.4 11.4 13.9 72.0 54.8 38.4 40.3 70.4 52.3 68.4 60.1 14.7 34.1 15.2 3.5 26.1 39.4 39.1 93.5 39.9 23.1 76.7 95.1 77.4 69.5 39.7 69.9 51.8 76.4 246.3 29.4 103.7 96.9 123.7 43.3 107.5 75.8 27.2 52.8 54.2 42.1 21.2 17.4 23.6 58.7 115.4 46.1 59.8 37.1 59.9 53.3 0.0 1.4 2.7 0.8 0.7 1.3 2.5 1.8 1.5 2.2 2.4 2.3 1.1 1.4 1.8 0.3 7.8 0.8 0.9 45.1 43.6 43.1 46.4 37.9 40.0 52.3 46.7 45.5 41.1 49.5 42.1 21.1 35.3 18.6 17.9 26.9 9.4 18.3 11.5 14.8 57.9 39.3 33.1 46.5 45.8 15.0 14.7 41.7 28.0 49.5 53.7 62.6 37.3 7.8 53.4 14.3 24.3 68.1 14.5 13.0 50.3 12.9 16.1 23.4 35.8 24.7 56.3 26.0 69.7 32.0 80.8 15.8 68.6 32.6 14.8 23.9 9.8 22.1 21.8 16.0 9.4 88.4 101.3 40.2 17.6 16.6 34.3 37.1 19.9 26.4 31.6 47.0 32.8 36.2 55.8 6.6 28.0 20.1 10.2 3.1 17.6 17.8 25.6 16.0 33.5 109.7 19.9 RETREG1 "FAM134B, FLJ20152, JK1" ENSG00000154153 "Reticulophagy regulator 1" Q9H6L5 5 16473038-16617038 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 91.4;skeletal muscle: 141.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Cytotrophoblasts: 53.7;Exocrine glandular cells: 59.3;Glandular and luminal cells: 197.7;Pancreatic endocrine cells: 51.5;Proximal tubular cells: 152.8" "Cancer enhanced" "Detected in all" "renal cancer: 28.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.3;T-cells: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 26.0;GAMG: 20.3;HSkMC: 28.8;MOLT-4: 20.4;RPTEC TERT1: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012077 Supported "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA012077: AB_2668621" "unprognostic (1.63e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-2)" "unprognostic (9.17e-3)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (4.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "prognostic favorable (5.25e-10)" "unprognostic (3.75e-1)" "unprognostic (9.96e-2)" "unprognostic (5.62e-2)" "unprognostic (2.58e-1)" 15.6 3.5 20.6 6.6 26.4 2.0 13.6 23.9 33.2 13.2 21.6 24.6 12.6 4.0 5.2 3.6 7.5 13.4 91.4 19.4 22.1 61.0 44.2 9.3 6.4 27.2 25.2 2.1 37.7 30.1 9.9 13.2 27.8 11.1 32.4 7.5 5.2 5.0 141.8 10.0 25.6 2.6 23.6 2.3 10.9 12.3 25.0 20.6 6.7 81.9 4.3 2.3 5.2 37.6 1.3 0.5 0.1 3.5 26.0 3.2 15.1 0.1 3.5 3.1 4.1 2.3 0.1 0.3 2.4 0.0 20.3 3.9 7.8 0.8 1.0 4.1 3.4 0.0 10.6 0.0 0.1 5.3 0.0 28.8 11.7 0.6 3.1 7.5 0.0 15.4 0.0 0.1 1.2 1.0 20.4 0.1 0.8 3.4 0.6 3.2 0.0 1.2 26.2 0.9 17.4 2.0 1.0 1.1 13.1 1.9 5.9 2.4 0.0 2.4 0.2 6.4 3.1 0.7 0.0 0.0 14.9 18.0 6.5 2.3 0.1 0.0 0.2 0.0 0.6 0.0 0.6 0.3 0.0 0.3 1.7 1.0 0.9 0.0 0.0 0.0 0.8 0.2 20.6 26.4 23.9 33.2 19.4 22.1 27.2 25.2 27.8 23.6 25.0 37.6 4.2 73.7 8.6 0.0 3.4 0.0 0.0 0.0 0.0 0.0 33.3 19.0 0.0 0.0 9.9 44.1 0.0 53.7 2.2 0.0 17.6 31.1 0.0 33.5 45.2 1.2 0.0 0.0 0.0 59.3 2.0 7.8 0.0 197.7 1.3 3.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.8 0.0 0.0 152.8 19.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 10.9 8.1 0.3 0.0 0.0 RGS3 "C2PA, FLJ20370, PDZ-RGS3" ENSG00000138835 "Regulator of G protein signaling 3" P49796 9 113444731-113597743 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.6;Horizontal cells: 158.2;Proximal tubular cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 248.4;HDLM-2: 413.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044234 Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA044234: " "prognostic unfavorable (9.93e-4)" "unprognostic (4.04e-2)" "unprognostic (5.33e-3)" "unprognostic (6.71e-3)" "unprognostic (1.49e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (6.62e-4)" "unprognostic (6.79e-2)" "unprognostic (9.17e-2)" "unprognostic (2.24e-1)" "unprognostic (8.59e-3)" "unprognostic (3.04e-1)" "unprognostic (2.51e-3)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (2.90e-1)" 60.5 31.5 32.0 18.1 37.3 9.3 43.7 33.7 29.7 17.9 49.7 30.4 16.9 20.8 11.4 10.8 15.2 42.4 95.0 24.0 31.5 70.9 54.5 64.2 23.9 32.2 44.3 10.3 23.9 12.3 16.6 32.3 32.5 26.3 15.8 10.3 10.8 10.2 48.2 15.2 20.0 18.0 28.2 31.9 27.6 31.2 58.0 7.9 24.5 19.2 11.4 26.5 15.4 34.0 4.5 16.6 40.1 37.0 12.2 18.1 2.9 41.2 248.4 32.9 27.9 40.8 14.7 17.9 29.7 33.6 32.8 10.6 0.6 16.0 19.2 413.2 0.1 1.7 13.0 24.8 24.8 0.4 5.5 32.4 16.6 91.4 13.2 72.6 125.4 1.0 0.3 17.1 60.5 18.7 1.2 1.9 10.6 28.6 13.7 1.3 19.8 2.9 67.7 8.1 31.3 4.2 3.9 31.3 24.7 19.6 21.5 3.8 61.2 109.7 11.8 5.1 79.1 8.6 1.5 2.7 126.2 3.8 51.6 10.2 6.8 3.7 24.7 7.1 16.7 2.4 5.7 20.3 6.6 2.4 2.4 10.8 18.5 42.3 6.0 0.3 3.8 15.6 32.0 37.3 33.7 29.7 24.0 31.5 32.2 44.3 32.5 28.2 58.0 34.0 49.5 16.0 13.9 14.4 5.6 12.0 9.9 7.4 4.6 1.4 9.1 10.7 55.8 72.9 8.4 22.0 6.2 4.6 23.5 28.0 82.2 65.1 38.8 9.9 14.9 111.6 0.0 6.1 2.4 30.4 3.7 29.3 27.0 4.0 47.7 12.8 66.0 35.2 15.6 158.2 3.4 7.4 4.1 14.3 13.8 17.4 4.7 14.6 55.2 21.5 10.3 3.5 50.4 3.5 24.4 31.0 23.4 13.9 4.5 5.0 20.5 195.7 7.5 6.4 6.6 8.4 35.4 9.9 1.8 4.1 11.4 3.0 18.4 55.5 11.5 12.9 RGS5 ENSG00000143248 "Regulator of G protein signaling 5" O15539 1 163111121-163321791 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Sertoli cells: 5114.5;Smooth muscle cells: 1592.3" "Cancer enhanced" "Detected in all" "renal cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1303.0;OE19: 692.4;SH-SY5Y: 4234.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001821 Supported Supported Vesicles,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA001821: AB_1079806" "unprognostic (3.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.65e-2)" "unprognostic (7.38e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.81e-3)" "unprognostic (7.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" 138.1 312.4 75.5 29.7 87.2 0.1 58.4 84.2 136.5 160.5 73.1 95.7 64.5 73.7 63.1 71.8 65.5 142.7 238.2 65.9 90.7 88.1 34.1 55.5 33.8 95.6 89.1 19.5 30.6 83.3 45.4 19.9 108.2 75.1 42.9 15.3 27.8 190.0 116.5 21.8 75.8 278.0 68.8 16.7 93.5 40.5 99.6 21.2 164.7 236.8 39.4 136.1 60.5 83.7 0.4 0.0 62.9 8.0 1.3 3.0 2.6 1.1 4.4 2.0 1.3 5.3 1.6 0.5 9.2 1.1 0.7 0.4 0.8 0.8 3.3 3.0 1.0 1.3 0.9 0.1 2.6 0.8 0.7 2.0 1.9 2.1 2.6 14.3 1303.0 0.3 0.2 1.2 4.7 0.0 0.9 2.2 38.7 692.4 1.4 0.4 0.1 3.6 0.7 0.0 5.2 4234.9 0.9 0.0 1.5 185.8 0.0 1.3 5.3 1.0 2.3 0.9 2.0 1.5 1.2 0.4 1.4 0.2 2.9 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.2 0.1 0.2 0.4 0.4 0.1 0.2 0.1 0.0 0.2 0.1 75.5 87.2 84.2 136.5 65.9 90.7 95.6 89.1 108.2 68.8 99.6 83.7 458.3 3.2 5.6 61.4 1.7 17.1 6.0 1.0 0.6 1.8 9.8 12.1 0.0 0.0 7.3 1.8 4.2 1.5 2.4 0.3 1.9 1.0 32.7 3.4 11.6 353.7 0.0 0.0 24.4 1.1 0.8 43.0 223.3 8.1 1.3 0.9 0.0 0.0 1.2 0.0 60.5 0.2 0.0 0.0 26.3 17.0 6.8 11.9 23.2 80.6 0.6 2.6 0.0 25.1 69.7 3.9 0.2 2.6 0.4 12.7 0.2 2.5 5.9 5.8 5114.5 44.9 1592.3 5.7 1.7 5.2 12.6 1.2 5.8 5.5 0.2 7.0 RHOT1 "ARHT1, FLJ11040, MIRO-1, MIRO1" ENSG00000126858 "Ras homolog family member T1" Q8IXI2 17 32142454-32253374 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010687, CAB068223, CAB068224" Supported NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" "CAB068223: AB_2665691, CAB068224: AB_2665692, HPA010687: AB_1079813" "unprognostic (3.28e-2)" "unprognostic (4.02e-3)" "unprognostic (6.85e-2)" "unprognostic (3.53e-1)" "unprognostic (1.57e-2)" "unprognostic (5.49e-2)" "unprognostic (1.59e-3)" "unprognostic (1.59e-2)" "unprognostic (7.02e-3)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "unprognostic (5.05e-1)" "unprognostic (1.01e-2)" "unprognostic (2.97e-2)" "unprognostic (2.58e-1)" "unprognostic (3.90e-1)" "unprognostic (4.08e-2)" 19.1 26.9 19.9 9.6 20.8 19.7 19.5 20.5 29.4 16.6 12.5 19.8 11.4 16.3 15.0 14.9 14.4 11.4 24.8 22.0 18.5 17.6 16.8 17.3 10.9 18.1 17.5 17.7 15.5 38.1 14.2 18.6 19.8 17.1 11.3 50.9 17.3 19.1 28.4 28.5 12.2 16.0 18.7 12.2 17.3 12.3 19.9 19.4 25.0 34.5 11.2 16.6 15.5 24.8 14.1 26.2 21.9 22.8 25.8 28.9 13.2 22.7 18.2 24.2 26.0 13.8 9.0 18.2 22.3 18.7 26.5 24.9 34.3 13.8 29.1 14.4 25.9 21.4 15.8 21.0 35.4 28.1 15.3 15.3 40.7 20.7 23.8 40.5 21.1 36.7 48.1 14.9 21.5 10.6 52.1 23.0 18.0 16.7 12.6 28.6 32.4 32.2 17.5 8.4 20.0 18.1 22.8 14.1 38.4 26.1 31.9 38.1 16.3 17.0 17.5 19.6 16.2 22.0 22.9 19.9 20.5 26.7 28.9 3.0 5.8 5.4 2.1 4.9 2.3 2.1 2.3 2.1 5.3 4.0 1.8 2.3 3.6 3.4 5.2 1.8 1.3 2.8 19.9 20.8 20.5 29.4 22.0 18.5 18.1 17.5 19.8 18.7 19.9 24.8 16.5 28.9 38.8 88.8 17.8 25.9 13.5 14.4 27.9 61.5 21.4 18.0 38.1 14.3 18.7 16.5 70.9 28.4 14.1 12.3 33.2 17.0 19.6 14.5 15.5 17.9 16.9 31.5 97.3 13.1 20.3 19.3 15.3 13.9 27.3 24.8 18.9 18.3 33.7 57.2 89.9 9.3 22.4 46.4 29.1 20.6 30.1 33.2 16.0 76.8 45.1 128.9 29.9 68.3 65.9 13.5 14.4 24.0 11.6 13.7 22.8 21.3 15.1 58.7 26.3 24.8 21.9 63.0 40.3 24.3 53.0 22.7 18.9 24.5 13.9 11.4 RIC8B "FLJ10620, hSyn, RIC8" ENSG00000111785 "RIC8 guanine nucleotide exchange factor B" Q9NVN3 12 106774621-106889316 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.4;Inhibitory neurons: 93.9;Microglial cells: 58.1;Oligodendrocyte precursor cells: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039970, HPA042746" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "HPA039970: , HPA042746: AB_2678143" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (9.87e-3)" "unprognostic (5.43e-2)" "unprognostic (3.28e-2)" "unprognostic (8.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.60e-1)" "unprognostic (1.99e-2)" "unprognostic (3.83e-1)" "unprognostic (1.10e-3)" "unprognostic (5.13e-2)" "unprognostic (3.65e-3)" "unprognostic (2.21e-1)" "unprognostic (3.18e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" 5.5 5.3 7.7 3.2 26.1 1.3 4.9 7.9 9.7 5.5 6.6 6.4 3.1 7.0 4.3 3.1 6.3 5.6 8.7 6.8 8.7 7.2 5.8 3.7 2.5 6.6 11.5 5.8 6.2 11.5 7.8 3.7 6.5 4.5 3.9 12.6 3.5 8.2 7.3 2.7 4.1 6.4 5.4 4.7 4.1 4.4 9.3 6.5 9.3 8.2 2.4 5.9 4.3 8.4 3.6 11.0 20.7 8.3 9.7 11.7 2.5 11.7 9.3 10.3 9.6 3.7 3.1 2.2 8.0 6.7 4.1 6.2 7.5 4.1 12.3 25.0 10.0 7.5 5.2 4.7 7.5 7.2 4.9 6.8 5.2 6.7 3.4 12.2 9.6 7.7 4.7 0.1 9.4 2.9 8.2 7.8 10.4 5.6 11.0 7.1 12.0 7.2 8.7 3.2 15.1 9.7 8.5 5.3 5.9 7.8 4.7 4.9 9.3 8.3 4.6 5.6 8.5 6.1 13.7 0.1 4.0 4.9 12.4 0.9 1.4 1.2 1.9 0.8 2.2 0.4 1.0 0.9 1.3 0.2 0.8 0.8 0.6 0.9 0.7 0.8 1.1 1.0 7.7 26.1 7.9 9.7 6.8 8.7 6.6 11.5 6.5 5.4 9.3 8.4 10.0 6.4 7.8 47.7 5.9 3.3 3.9 5.5 5.2 14.4 8.5 7.4 33.9 25.8 5.8 3.7 10.4 7.1 5.0 10.9 7.9 21.7 5.7 12.7 17.5 11.2 18.6 5.5 96.4 4.0 3.7 10.5 7.7 7.3 8.2 10.4 15.0 9.2 3.6 6.7 93.9 7.8 8.2 6.6 3.9 5.0 12.8 4.6 7.2 58.1 3.8 5.5 14.4 76.9 52.9 6.6 4.8 19.2 2.6 1.7 7.2 6.7 10.8 45.0 13.1 18.6 9.3 18.4 8.8 2.6 2.8 1.4 7.6 10.6 6.7 1.5 RILPL1 FLJ39378 ENSG00000188026 "Rab interacting lysosomal protein like 1" Q5EBL4 12 123470054-123533719 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 62.4;skeletal muscle: 88.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041314 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA041314: AB_10795587" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (3.71e-2)" "unprognostic (5.36e-2)" "unprognostic (3.12e-2)" "unprognostic (2.99e-3)" "unprognostic (1.94e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (2.30e-2)" "unprognostic (8.30e-2)" "unprognostic (4.25e-2)" "unprognostic (2.98e-1)" "unprognostic (2.32e-1)" "unprognostic (6.07e-3)" "unprognostic (2.81e-1)" 7.8 9.0 17.1 3.1 21.1 2.6 7.5 18.6 18.3 10.7 17.9 10.5 1.3 12.0 4.1 5.1 9.5 3.4 62.4 15.2 16.7 6.8 4.2 6.8 1.8 19.0 19.7 8.5 3.7 6.6 6.4 7.3 18.6 9.1 1.4 3.0 6.8 7.4 88.9 6.8 4.2 6.3 15.9 4.4 5.5 4.1 18.0 1.5 13.3 41.1 1.0 9.5 7.5 27.1 8.3 11.4 10.1 7.9 11.1 10.4 10.6 14.6 8.1 7.8 6.9 7.1 1.9 0.3 7.1 14.3 5.6 8.9 7.5 7.0 3.1 8.4 13.8 1.1 8.1 10.6 19.4 0.4 3.0 11.9 13.6 8.7 12.5 19.5 8.0 1.5 6.6 0.4 8.0 13.8 0.9 2.7 7.4 2.4 11.9 1.3 5.5 0.4 5.6 8.5 1.6 9.3 7.8 6.7 17.9 5.5 9.0 0.2 16.0 10.2 5.1 14.8 9.4 1.7 0.9 0.2 10.4 0.0 6.5 0.4 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.5 0.4 1.1 0.3 0.3 0.3 0.2 0.2 17.1 21.1 18.6 18.3 15.2 16.7 19.0 19.7 18.6 15.9 18.0 27.1 13.0 38.5 11.7 32.3 0.7 4.6 5.1 3.4 6.2 14.1 4.6 14.7 9.8 4.3 7.2 11.0 6.2 9.1 0.7 0.2 1.9 2.2 1.8 6.3 18.0 8.5 0.0 0.0 28.8 2.2 6.2 9.4 1.1 7.4 1.3 18.9 9.7 1.6 5.7 23.5 16.4 1.3 0.0 1.3 2.4 1.6 15.5 3.3 5.4 18.7 0.9 21.4 0.0 13.6 64.9 2.2 0.5 8.2 0.3 5.1 0.1 2.6 4.1 6.4 6.6 14.4 9.9 0.9 2.9 2.3 3.8 9.3 2.0 21.5 0.7 3.3 RITA1 "C12orf52, FLJ14827, RITA" ENSG00000139405 "RBPJ interacting and tubulin associated 1" Q96K30 12 113185526-113192368 "Predicted intracellular proteins" "Neurogenesis, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 49.0;Proximal enterocytes: 62.0;Proximal tubular cells: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039094, HPA039095, HPA061531" Supported Supported Nucleoplasm No No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA039094: AB_10671037, HPA039095: AB_2676345, HPA061531: AB_2684554" "unprognostic (7.10e-2)" "unprognostic (4.26e-2)" "unprognostic (2.78e-2)" "unprognostic (3.55e-2)" "unprognostic (2.56e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.47e-2)" "unprognostic (2.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.98e-1)" "unprognostic (2.59e-3)" "unprognostic (1.44e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 6.8 25.4 17.0 7.1 17.4 7.1 7.7 16.0 20.2 8.7 14.6 9.7 13.1 8.1 6.4 14.3 14.0 5.9 15.0 17.5 15.7 15.9 29.6 6.9 11.1 15.1 15.3 10.6 10.6 9.5 12.6 4.7 15.2 10.1 5.9 4.4 13.7 8.3 31.7 10.8 14.2 4.6 12.6 9.5 8.8 7.4 16.9 9.7 10.4 27.2 8.2 8.5 8.1 15.3 27.0 34.3 8.7 23.0 11.5 8.8 15.6 17.2 35.3 24.9 19.8 40.7 13.0 50.8 26.0 14.6 21.4 20.0 20.0 22.3 14.4 31.3 28.4 17.4 16.6 26.6 18.7 23.4 14.0 13.6 20.2 24.6 13.8 34.5 20.7 24.7 34.0 9.2 14.9 38.6 26.1 63.1 29.2 22.9 41.8 23.2 9.3 43.2 20.3 37.8 28.9 16.6 21.7 45.2 38.2 10.6 38.2 35.5 13.7 15.7 22.3 18.2 24.7 31.6 28.6 56.0 23.4 19.4 22.5 43.7 14.6 9.9 15.3 6.6 15.3 11.0 13.5 13.9 16.5 11.8 13.2 14.6 0.3 20.7 8.6 22.5 16.1 13.5 17.0 17.4 16.0 20.2 17.5 15.7 15.1 15.3 15.2 12.6 16.9 15.3 8.1 0.0 11.3 2.9 11.1 6.4 7.1 14.0 7.4 7.4 14.7 14.7 6.6 12.8 9.1 14.7 4.2 19.3 9.8 17.0 49.0 19.2 10.8 16.7 7.3 9.3 11.4 8.8 6.5 16.4 16.9 7.0 8.2 7.3 0.0 8.7 8.6 37.5 14.2 15.2 6.7 12.5 8.2 7.8 2.4 29.6 9.9 6.3 5.4 2.8 5.9 11.0 19.6 2.0 3.7 15.2 12.9 8.2 14.7 10.1 62.0 51.9 17.1 6.0 6.6 7.7 7.5 4.5 7.8 13.8 6.5 10.1 9.0 17.2 12.7 7.5 RMND5A "FLJ13910, GID2, GID2A, p44CTLH, RMD5" ENSG00000153561 "Required for meiotic nuclear division 5 homolog A" Q9H871 2 86720291-86778041 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046795, HPA060843" Uncertain Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA046795: AB_10963573, HPA060843: AB_2684378" "unprognostic (4.54e-2)" "unprognostic (9.23e-2)" "unprognostic (3.45e-2)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.32e-2)" "unprognostic (4.40e-2)" "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (1.49e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-2)" "unprognostic (8.34e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.56e-1)" 17.8 11.2 19.4 9.3 24.3 31.2 16.2 54.5 25.2 13.4 20.0 19.7 16.4 13.0 13.3 31.3 12.9 6.8 38.2 21.6 17.5 18.2 42.9 10.5 11.6 18.4 20.6 11.1 11.6 20.8 7.9 11.6 18.3 12.4 21.2 18.9 11.4 11.1 63.6 22.4 15.5 13.7 20.4 14.3 12.1 7.8 18.7 31.4 13.0 37.0 14.0 10.0 17.0 28.8 19.4 10.2 17.6 10.5 22.9 10.1 36.3 7.5 6.1 9.7 11.0 37.6 20.3 66.7 22.4 6.9 11.3 22.6 45.1 15.8 15.0 19.4 34.4 58.7 21.8 34.2 23.1 43.2 18.6 15.4 30.5 10.2 35.2 11.0 17.0 48.7 37.7 37.3 7.9 12.6 40.1 36.9 29.8 23.1 13.0 47.3 54.2 42.3 20.1 22.8 32.6 25.1 16.9 33.5 27.9 24.8 16.8 36.8 16.3 6.7 12.9 12.2 11.7 16.7 18.8 45.0 5.6 51.3 7.8 37.5 11.9 8.1 8.1 10.1 9.7 4.7 6.2 9.1 9.4 6.4 8.4 11.6 27.5 8.8 12.5 7.4 4.7 8.6 19.4 24.3 54.5 25.2 21.6 17.5 18.4 20.6 18.3 20.4 18.7 28.8 32.8 12.8 15.9 15.3 27.0 41.9 23.4 10.4 46.7 26.3 25.5 15.6 93.2 24.3 10.5 11.0 6.2 21.0 36.2 73.3 23.5 13.1 13.7 33.8 28.7 26.0 39.5 105.2 27.3 14.1 18.6 20.1 24.5 35.3 8.2 16.3 25.0 76.7 15.1 23.5 27.2 57.4 14.2 34.4 42.7 5.6 19.3 26.3 32.0 14.0 23.7 15.3 30.9 10.6 42.3 21.9 30.9 17.3 30.1 34.8 38.1 34.4 26.6 16.3 6.6 22.7 20.1 17.9 27.8 50.0 54.8 24.6 31.4 24.6 28.7 34.0 RNF10 "KIAA0262, RIE2" ENSG00000022840 "Ring finger protein 10" Q8N5U6 12 120533480-120577588 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 286.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052643 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Mitochondria "HPA052643: AB_2681897" "unprognostic (1.54e-1)" "unprognostic (3.04e-1)" "unprognostic (5.40e-2)" "unprognostic (2.83e-3)" "unprognostic (1.09e-2)" "unprognostic (3.58e-2)" "prognostic unfavorable (5.30e-5)" "unprognostic (5.02e-2)" "unprognostic (3.06e-1)" "unprognostic (1.68e-1)" "unprognostic (1.93e-1)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-1)" "unprognostic (4.10e-2)" "unprognostic (2.40e-1)" 79.5 104.3 99.0 52.7 101.2 184.8 68.1 97.2 135.0 63.9 108.8 90.1 58.8 61.6 96.1 103.0 58.5 50.1 191.2 101.7 98.4 108.3 81.7 74.4 53.6 99.0 102.9 65.6 75.2 75.8 71.3 65.9 97.8 69.0 65.8 76.6 68.1 61.7 307.2 77.8 61.2 77.8 99.3 78.7 81.0 96.8 100.9 57.9 60.7 208.8 69.5 73.2 69.3 107.2 109.7 141.6 68.3 109.3 130.9 103.0 80.6 100.7 113.9 81.8 86.4 117.1 49.3 129.5 89.4 167.3 64.0 73.9 126.6 136.5 116.0 127.5 71.0 132.1 77.5 123.0 175.3 120.0 89.5 105.5 155.0 115.1 156.8 141.8 168.5 95.7 134.2 86.7 124.3 125.3 79.4 131.1 104.0 101.7 139.9 69.8 87.5 185.4 164.4 221.1 66.9 72.7 140.0 89.5 78.9 94.2 144.2 68.6 134.8 59.3 65.7 95.5 65.9 74.7 146.8 90.8 97.5 80.2 65.0 154.2 53.8 173.8 45.5 45.8 48.9 35.7 44.7 52.4 60.0 31.2 39.5 40.6 118.0 46.1 54.3 30.7 60.7 52.9 99.0 101.2 97.2 135.0 101.7 98.4 99.0 102.9 97.8 99.3 100.9 107.2 56.2 25.6 32.6 30.3 54.0 61.9 51.1 27.1 52.3 39.9 63.8 42.9 99.3 32.9 28.4 47.8 22.9 62.1 58.9 93.5 164.4 49.7 72.7 54.1 53.2 45.9 49.2 286.5 43.1 58.7 69.4 47.8 64.7 78.9 36.8 42.0 42.8 48.8 36.9 55.5 42.9 50.3 34.6 52.5 63.1 41.7 56.8 54.7 56.9 16.9 48.7 43.3 56.7 32.2 52.4 59.8 49.1 54.9 71.2 63.1 73.8 70.0 21.6 54.5 52.6 52.3 55.0 118.0 55.2 74.5 65.8 111.8 59.1 74.1 47.3 77.8 RNF11 "CGI-123, MGC51169, Sid1669p" ENSG00000123091 "Ring finger protein 11" Q9Y3C5 1 51236273-51273447 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 22.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045781 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "HPA045781: AB_2679450" "unprognostic (2.66e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.45e-2)" "unprognostic (8.30e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (3.57e-2)" "unprognostic (3.75e-2)" "unprognostic (2.66e-1)" "unprognostic (9.04e-2)" "unprognostic (2.11e-1)" "prognostic favorable (3.14e-4)" "unprognostic (2.14e-2)" "unprognostic (1.08e-1)" "unprognostic (3.48e-1)" "unprognostic (3.92e-2)" 70.1 70.6 79.0 24.5 82.5 71.2 46.9 67.7 117.5 49.8 51.5 45.2 34.3 48.5 51.9 66.8 35.8 40.5 69.0 88.2 82.5 65.5 61.2 42.5 20.7 71.3 82.9 77.2 27.4 67.6 51.4 47.1 79.6 51.3 30.4 64.7 37.3 48.5 107.1 35.2 34.7 48.2 78.4 33.3 34.6 29.2 82.6 23.6 72.1 94.5 25.8 53.4 46.1 75.2 66.3 15.7 32.6 44.7 114.2 91.8 49.6 72.3 83.5 62.4 76.5 18.4 24.6 0.5 72.1 133.4 77.1 22.2 36.6 53.9 105.2 124.5 40.4 43.2 23.7 28.7 78.6 20.4 113.0 67.8 87.3 68.3 71.5 97.4 80.2 23.6 14.9 26.2 130.4 24.1 24.9 17.2 46.5 33.1 40.6 19.1 59.8 29.4 111.2 61.4 31.7 34.3 53.9 61.8 79.3 77.9 35.8 28.9 85.8 97.6 51.9 76.1 82.8 58.9 62.9 6.6 51.3 40.5 60.9 22.1 1.6 7.1 2.6 2.3 3.9 0.9 2.6 3.6 1.7 0.7 2.8 3.6 6.2 3.6 2.1 6.7 3.2 3.6 79.0 82.5 67.7 117.5 88.2 82.5 71.3 82.9 79.6 78.4 82.6 75.2 54.7 57.7 41.6 19.9 30.0 136.9 108.7 37.5 84.8 37.0 70.5 33.1 120.6 37.1 41.1 40.5 25.0 38.6 63.4 62.7 105.7 56.7 154.4 44.5 46.0 61.3 77.0 110.7 56.4 60.7 43.3 61.7 40.2 53.0 54.7 21.4 57.1 63.4 30.6 35.3 62.1 38.5 57.0 41.5 84.2 171.5 57.5 88.0 65.8 23.4 39.7 75.3 37.0 26.2 38.0 64.7 35.5 86.9 43.8 117.7 51.9 132.6 33.8 37.5 39.5 47.8 55.6 59.1 33.9 97.7 168.8 196.9 49.6 39.4 29.5 173.9 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 75.0 110.6 141.9 53.0 146.7 69.0 73.1 146.4 179.9 93.2 138.6 111.5 66.6 94.9 76.4 122.1 84.3 45.3 131.8 141.5 146.4 106.7 184.2 77.5 64.5 146.3 145.4 87.4 115.1 105.8 96.8 50.7 146.3 95.0 65.7 98.1 92.5 70.5 152.9 127.8 100.5 52.8 142.4 113.8 111.8 110.6 150.3 98.1 93.4 94.2 71.6 106.7 90.4 153.3 102.6 143.1 61.1 73.7 132.8 68.7 92.7 63.4 76.1 119.7 93.4 96.2 43.3 71.5 120.3 93.5 63.9 147.5 103.2 114.8 86.1 74.5 166.1 121.9 164.4 94.9 100.6 59.0 245.0 79.6 176.5 129.8 116.2 74.6 77.2 101.0 49.9 237.5 96.2 66.3 92.8 70.6 75.4 102.0 86.8 62.8 61.9 91.5 137.3 77.4 49.2 61.1 56.0 92.9 81.9 83.1 87.3 55.9 49.5 76.6 48.3 66.8 119.3 79.5 88.0 23.7 98.4 80.6 77.9 108.4 88.8 236.9 195.3 94.0 153.4 100.4 148.0 195.7 73.9 98.7 103.2 152.2 219.8 118.8 117.7 75.9 153.0 177.0 141.9 146.7 146.4 179.9 141.5 146.4 146.3 145.4 146.3 142.4 150.3 153.3 36.9 0.0 3.9 12.4 54.3 68.6 44.4 65.8 51.8 43.2 56.6 44.7 15.8 77.2 38.9 49.7 20.9 120.1 64.7 65.2 56.7 78.5 59.6 29.8 25.1 36.4 31.8 60.6 11.3 66.7 139.7 36.3 36.2 32.2 14.0 26.3 45.7 95.1 58.4 18.5 11.2 45.7 65.1 41.3 43.6 86.5 48.7 36.1 39.2 6.5 53.1 46.9 114.4 10.1 17.9 60.7 44.9 53.8 59.1 32.6 108.2 64.0 31.1 32.3 39.5 28.4 35.1 127.1 106.7 61.4 83.3 125.2 82.5 37.2 59.6 48.0 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 371.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 38.2 75.9 60.4 29.2 63.4 40.4 44.5 64.6 66.0 44.9 59.4 59.5 61.6 44.8 45.8 37.5 54.1 46.1 81.7 59.2 60.6 115.6 126.2 38.7 43.1 65.0 60.6 60.4 41.6 55.5 17.2 30.1 62.6 44.0 62.4 42.9 43.9 31.7 89.6 44.6 76.5 30.5 62.8 38.8 55.3 29.5 61.8 60.7 48.6 76.5 43.4 45.1 38.8 67.0 51.2 66.1 43.7 167.5 46.9 31.3 34.0 20.6 26.5 44.4 48.7 89.1 42.1 65.2 70.8 47.9 62.5 41.7 80.3 45.1 45.2 41.8 107.5 53.9 69.5 184.4 55.0 0.2 101.2 32.3 60.3 73.3 53.6 77.2 89.1 115.0 136.6 67.8 63.8 71.9 66.5 151.5 0.3 71.8 28.7 44.4 48.2 88.2 124.0 32.6 44.8 92.1 39.9 42.4 46.7 39.9 87.0 183.0 40.3 48.1 44.7 0.5 79.1 38.6 63.5 79.3 33.2 116.4 29.6 64.8 45.7 75.8 64.8 65.9 55.6 64.6 52.5 57.6 64.7 56.2 57.5 58.3 22.1 79.6 46.7 264.6 58.2 75.0 60.4 63.4 64.6 66.0 59.2 60.6 65.0 60.6 62.6 62.8 61.8 67.0 38.3 19.2 41.1 2.9 52.7 95.7 70.0 146.6 52.3 23.6 61.8 56.5 62.9 87.2 79.5 92.0 0.0 78.1 70.3 151.9 283.7 110.8 21.6 47.2 31.7 50.9 73.2 126.3 3.4 91.3 101.7 44.6 28.5 31.7 56.3 41.5 47.8 131.5 68.9 33.7 3.5 83.0 132.2 51.1 171.7 22.6 59.4 43.3 85.4 1.0 69.5 91.3 65.9 1.5 10.0 78.5 173.0 72.6 45.5 58.4 270.6 371.6 73.4 27.6 65.7 50.6 63.0 55.7 37.7 44.4 84.4 84.1 53.8 42.8 100.3 56.5 RNF7 "CKBBP1, ROC2, SAG" ENSG00000114125 "Ring finger protein 7" Q9UBF6 3 141738249-141747560 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 898.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036995 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA036995: AB_10673627" "unprognostic (5.68e-2)" "unprognostic (4.94e-3)" "unprognostic (1.83e-1)" "unprognostic (3.24e-1)" "unprognostic (9.11e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (4.53e-2)" "unprognostic (1.24e-2)" "unprognostic (3.98e-3)" "unprognostic (5.17e-3)" "unprognostic (8.58e-3)" "prognostic unfavorable (1.54e-9)" "unprognostic (4.60e-1)" "unprognostic (2.20e-1)" "unprognostic (3.69e-2)" "unprognostic (2.36e-2)" 67.1 114.5 62.7 40.8 65.6 65.0 63.5 63.4 80.0 69.5 72.2 98.2 69.7 58.7 70.8 86.5 61.0 46.1 102.8 64.2 67.2 92.3 83.9 58.4 44.5 64.4 64.8 73.8 80.3 44.0 81.5 51.2 65.7 77.6 59.8 37.6 59.8 43.8 142.0 72.0 64.1 47.8 65.1 58.7 68.3 71.2 66.3 45.4 52.6 113.1 44.1 77.9 71.9 65.9 172.6 67.4 98.1 80.0 91.6 125.7 65.5 94.6 87.5 78.2 82.6 79.4 82.5 57.7 214.5 104.7 192.7 80.8 61.5 88.1 98.3 56.0 119.1 56.6 64.8 116.4 122.6 89.7 52.9 118.2 96.9 63.4 105.5 104.3 112.3 96.1 61.6 77.0 117.2 131.0 56.6 100.1 105.1 170.7 113.3 61.1 63.1 124.0 169.2 74.0 54.8 68.1 108.7 108.8 161.4 126.4 102.4 114.8 86.2 78.1 75.6 139.2 80.5 73.7 66.5 121.2 122.4 98.4 90.3 119.0 128.2 87.7 78.0 116.4 77.7 82.6 82.8 83.2 112.9 74.1 79.6 83.7 45.5 61.8 125.7 103.4 108.8 121.6 62.7 65.6 63.4 80.0 64.2 67.2 64.4 64.8 65.7 65.1 66.3 65.9 128.7 60.9 55.2 7.5 81.4 132.4 143.0 290.5 150.2 34.3 159.7 207.3 104.1 105.8 151.1 101.2 27.1 183.8 133.2 262.0 254.3 225.1 348.9 99.3 112.0 134.9 125.7 41.4 12.9 247.3 249.1 114.2 73.9 100.0 72.9 206.4 129.9 132.0 214.4 28.6 12.6 195.2 134.3 126.7 123.5 898.4 117.8 137.6 144.1 18.7 174.1 111.7 140.1 10.6 19.6 233.2 261.4 121.9 102.0 181.8 295.1 324.1 105.7 56.7 85.5 84.3 126.2 212.2 129.1 183.7 144.6 129.8 112.7 281.4 174.5 185.9 RNF8 KIAA0646 ENSG00000112130 "Ring finger protein 8" O76064 6 37353979-37394734 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 76.0" "Not detected" "Not detected" "HPA050731, HPA064925" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA050731: AB_2681222, HPA064925: AB_2685385" "unprognostic (1.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.39e-2)" "unprognostic (8.20e-2)" "unprognostic (5.17e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (3.33e-5)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (2.26e-3)" "unprognostic (3.38e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (3.41e-2)" "unprognostic (3.66e-3)" "unprognostic (1.09e-1)" 5.0 7.8 10.0 3.5 10.1 4.6 5.2 11.8 14.3 7.7 9.3 6.3 3.1 7.0 2.1 10.6 6.0 4.0 8.6 10.1 10.5 8.8 4.8 5.9 4.2 10.2 10.6 7.6 4.5 7.4 6.6 4.8 10.3 6.0 3.6 9.0 6.2 5.2 8.1 7.6 5.0 4.9 9.4 4.7 5.2 11.2 11.2 5.8 4.5 10.6 6.6 6.5 7.8 9.9 12.5 7.3 17.3 20.7 13.7 19.6 4.9 12.6 15.5 23.4 25.6 11.0 6.8 15.3 7.5 12.4 20.1 11.4 24.4 16.0 24.4 16.2 23.7 26.5 12.0 16.6 7.8 14.3 18.7 9.8 15.2 14.0 16.2 14.3 22.9 17.9 18.1 5.2 13.6 8.3 17.4 17.5 12.1 6.3 9.4 13.5 16.0 10.6 12.1 8.7 34.0 11.4 9.5 10.6 18.0 11.3 9.5 13.6 10.4 15.4 13.5 14.7 18.8 15.2 21.8 76.0 7.5 20.1 18.0 1.0 4.3 2.5 9.5 5.8 8.8 8.1 7.0 9.2 7.8 4.9 6.1 8.1 0.5 7.9 8.8 3.3 9.1 5.2 10.0 10.1 11.8 14.3 10.1 10.5 10.2 10.6 10.3 9.4 11.2 9.9 21.0 19.2 25.9 13.4 15.0 18.2 22.2 26.0 26.2 26.7 16.5 20.4 31.1 12.8 18.5 25.8 39.6 24.8 18.2 10.3 15.6 24.7 41.1 68.5 32.2 19.2 22.2 18.7 17.0 18.9 25.8 28.0 16.3 52.3 28.5 37.0 27.8 16.5 17.5 50.5 15.9 16.5 14.2 13.9 17.7 30.2 26.8 24.0 10.6 11.2 19.6 25.4 37.0 12.5 20.5 28.8 18.1 30.9 13.7 31.8 11.8 20.6 23.8 32.3 13.1 23.2 20.8 46.5 34.5 34.2 22.0 5.9 19.3 22.0 18.0 21.9 ROMO1 "bA353C18.2, C20orf52, MTGMP" ENSG00000125995 "Reactive oxygen species modulator 1" P60602 20 35699272-35700984 "Predicted intracellular proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1349.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012782 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA012782: AB_1845685" "unprognostic (1.55e-1)" "unprognostic (3.86e-2)" "unprognostic (3.00e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (1.27e-3)" "unprognostic (5.84e-2)" "unprognostic (6.15e-2)" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (7.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (2.70e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" 126.3 185.8 164.8 71.6 170.7 112.3 125.8 174.7 216.3 112.3 182.8 131.7 99.8 113.0 81.6 185.6 102.9 50.8 246.2 165.5 169.8 188.4 206.2 99.8 79.2 171.0 170.0 111.3 134.7 122.3 163.6 63.0 170.5 126.4 66.3 33.0 133.9 79.6 259.2 122.0 105.1 51.7 170.2 104.6 126.0 121.6 175.1 102.3 122.5 168.9 59.3 108.6 119.7 176.4 304.5 493.7 164.5 202.1 125.3 169.2 269.2 165.7 196.2 256.6 251.0 1196.7 263.5 154.6 370.6 125.5 380.3 320.6 88.5 438.3 64.9 84.6 615.1 267.2 547.2 1349.5 259.4 166.6 134.7 216.2 204.3 182.1 133.1 118.5 209.7 285.9 224.6 309.7 124.7 966.0 373.0 456.6 251.8 327.6 867.8 246.5 319.0 342.3 246.9 516.1 229.3 236.0 288.6 546.5 306.6 150.0 502.6 353.8 172.5 425.0 240.1 281.1 279.8 504.6 481.5 409.3 371.0 130.9 249.7 602.8 590.1 459.5 398.5 511.9 378.4 587.2 408.8 393.7 573.0 523.1 346.7 384.9 330.0 391.8 486.2 1054.9 538.0 726.4 164.8 170.7 174.7 216.3 165.5 169.8 171.0 170.0 170.5 170.2 175.1 176.4 168.1 102.5 187.2 2.3 147.5 118.3 87.5 339.7 124.7 28.7 235.9 237.9 662.8 264.5 256.3 257.5 8.4 284.8 101.0 691.8 403.0 364.1 23.8 334.5 192.2 150.9 328.1 152.3 2.2 571.6 256.0 194.8 253.8 268.5 193.2 125.9 166.7 641.1 219.9 20.2 2.1 412.9 203.4 157.9 164.3 50.9 130.5 165.0 236.5 3.7 266.4 176.1 108.1 1.0 4.8 567.4 574.0 128.2 323.2 124.8 573.0 753.7 355.8 39.5 118.3 109.7 262.4 283.9 225.4 270.7 153.2 326.9 141.5 64.4 387.0 115.6 RPP25L "bA296L22.5, C9orf23, MGC29635" ENSG00000164967 "Ribonuclease P/MRP subunit p25 like" Q8N5L8 9 34610486-34612104 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 118.4" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 132.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052187, HPA059698" Uncertain Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA052187: AB_2681755, HPA059698: AB_2684106" "unprognostic (1.56e-1)" "unprognostic (1.43e-2)" "unprognostic (7.44e-2)" "unprognostic (1.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.78e-1)" "unprognostic (4.78e-2)" "unprognostic (2.56e-1)" "unprognostic (1.66e-1)" "unprognostic (2.53e-2)" "unprognostic (3.39e-2)" "unprognostic (2.44e-1)" "prognostic favorable (3.01e-9)" "unprognostic (4.63e-3)" "unprognostic (6.20e-2)" "unprognostic (3.40e-1)" "prognostic favorable (8.21e-4)" 17.2 23.2 30.5 13.8 31.7 9.7 18.3 32.7 36.2 20.6 28.4 26.4 27.5 19.9 12.5 28.2 20.1 14.5 46.8 30.5 31.5 30.6 51.4 11.8 20.7 31.9 30.6 19.5 23.0 24.0 17.4 12.2 32.3 24.5 14.4 4.8 23.1 15.1 118.4 17.5 26.4 10.5 30.8 26.5 21.9 16.0 33.0 22.5 18.5 103.1 13.9 20.5 18.5 30.2 42.6 54.0 21.9 21.4 21.4 20.2 21.5 18.1 18.5 28.9 33.1 24.3 28.2 32.8 27.1 11.0 13.5 28.1 33.2 44.2 10.4 66.1 44.5 19.5 37.9 36.2 46.1 20.5 28.3 35.2 42.4 24.3 55.3 25.1 30.8 44.5 31.6 34.1 22.7 45.8 42.9 76.4 20.1 43.4 48.7 37.2 23.0 33.2 31.9 22.1 14.6 8.5 32.9 36.6 21.6 10.8 33.6 35.7 14.5 9.1 26.3 22.3 15.1 16.4 30.8 38.6 27.6 41.3 44.7 71.2 55.6 56.4 38.2 48.5 47.3 57.1 44.5 40.3 47.8 67.3 51.8 49.8 51.9 56.6 57.5 39.3 68.4 39.6 30.5 31.7 32.7 36.2 30.5 31.5 31.9 30.6 32.3 30.8 33.0 30.2 12.9 0.0 15.1 6.5 20.7 11.1 50.4 61.9 24.5 7.8 30.9 39.9 34.4 22.8 30.5 20.2 2.1 61.8 14.4 55.7 99.7 31.0 3.3 10.3 21.5 17.5 33.6 12.6 3.0 19.8 38.1 18.4 17.9 13.7 10.2 16.4 27.1 77.5 32.0 0.0 3.9 44.7 38.7 33.6 10.4 6.0 22.4 18.4 12.4 3.7 33.1 25.6 51.5 2.0 3.4 18.9 61.6 15.4 14.7 40.8 132.7 82.2 21.0 12.3 6.6 18.2 18.8 50.3 24.0 30.6 14.8 41.9 17.4 47.7 50.1 44.4 RPS10-NUDT3 ENSG00000270800 "RPS10-NUDT3 readthrough" 6 34284887-34426071 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 58.7;Club cells: 19.2;granulocytes: 10.1;Respiratory ciliated cells: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 27.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047027, HPA047268, HPA048084, HPA055953" Uncertain Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA047027: AB_2679907, HPA047268: AB_2680007, HPA048084: AB_2680255, HPA055953: AB_2682984" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.85e-2)" "unprognostic (7.54e-3)" "unprognostic (1.28e-2)" "unprognostic (6.85e-2)" "unprognostic (8.95e-2)" "unprognostic (2.67e-1)" "unprognostic (5.07e-2)" "unprognostic (1.36e-1)" "unprognostic (3.63e-1)" "unprognostic (5.17e-8)" "unprognostic (5.80e-2)" "unprognostic (9.49e-2)" "unprognostic (2.23e-1)" "unprognostic (1.42e-1)" 7.7 6.6 5.9 6.3 5.2 9.5 5.5 3.3 9.0 7.2 0.0 5.0 1.4 4.1 0.1 9.6 4.3 1.5 17.0 6.0 6.3 8.6 10.2 6.3 3.2 7.1 6.7 6.3 7.7 2.0 6.1 4.5 7.3 5.7 1.3 1.4 5.6 0.6 18.6 4.9 4.4 2.9 6.8 6.8 5.1 8.9 7.3 3.8 5.8 8.6 2.3 5.8 7.2 4.8 17.6 6.0 16.0 27.3 11.6 8.0 16.2 13.0 7.0 10.3 10.3 6.7 9.2 22.9 22.2 8.7 23.4 11.5 23.7 7.1 12.5 15.1 9.9 35.1 11.3 19.4 4.2 33.2 38.4 3.2 14.9 15.2 31.6 14.2 10.1 20.7 35.9 22.7 13.2 17.8 33.9 16.4 7.9 38.5 5.8 18.7 13.5 15.0 10.5 19.1 24.6 8.7 9.6 10.0 34.1 10.1 15.1 59.6 7.9 15.3 22.9 7.0 18.2 11.3 18.3 28.8 2.1 20.2 23.7 11.2 5.9 27.3 3.2 6.8 3.3 6.0 3.7 3.6 7.5 5.9 3.6 3.4 4.3 5.0 6.9 5.3 3.7 5.4 5.9 5.2 3.3 9.0 6.0 6.3 7.1 6.7 7.3 6.8 7.3 4.8 0.0 35.3 58.7 2.6 0.0 0.8 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 2.1 0.0 0.0 8.3 0.4 0.1 3.8 0.0 0.3 10.1 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.5 0.0 0.0 4.1 0.0 1.0 0.0 0.0 0.0 0.5 4.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 2.3 0.0 0.0 0.2 RPUSD3 MGC29784 ENSG00000156990 "RNA pseudouridine synthase D3" Q6P087 3 9837849-9844602 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 249.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037551, HPA037552" Uncertain Approved Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA037551: AB_2675538, HPA037552: AB_10672600" "unprognostic (1.57e-1)" "unprognostic (8.88e-2)" "unprognostic (5.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.05e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.31e-1)" "unprognostic (2.36e-1)" "unprognostic (3.00e-2)" "unprognostic (2.56e-2)" "unprognostic (1.48e-1)" "unprognostic (5.17e-3)" "unprognostic (2.02e-1)" "unprognostic (2.16e-1)" "unprognostic (2.94e-2)" "unprognostic (8.83e-2)" 18.8 28.8 25.1 13.2 25.4 21.3 19.8 24.3 31.3 20.3 22.0 25.3 17.6 21.5 14.7 32.3 20.0 8.7 37.2 26.5 25.4 24.7 30.7 16.1 17.4 23.8 24.1 17.8 24.5 26.1 20.3 16.7 23.8 19.9 16.5 15.5 19.9 17.4 72.7 27.4 20.1 16.7 21.6 21.0 22.8 54.3 25.3 15.2 16.0 48.2 21.3 24.2 21.0 26.0 30.5 44.8 33.6 21.7 55.1 40.5 249.3 25.9 36.7 41.9 44.3 39.4 30.6 52.4 31.6 29.0 61.7 25.6 75.2 46.3 33.2 40.7 78.9 69.8 39.6 42.5 43.1 43.5 42.3 50.0 63.3 48.9 56.5 34.2 55.9 69.3 52.7 35.4 41.9 72.0 59.6 78.9 36.4 44.4 66.3 41.5 27.5 88.5 46.2 23.0 25.9 21.5 32.6 41.0 69.9 47.9 70.3 46.3 33.6 16.7 30.0 29.8 38.4 52.3 67.4 70.0 35.1 81.3 39.5 35.4 51.0 26.5 44.1 38.2 45.7 50.3 41.4 42.3 46.8 41.9 46.3 41.7 12.3 84.9 26.7 45.0 64.9 41.5 25.1 25.4 24.3 31.3 26.5 25.4 23.8 24.1 23.8 21.6 25.3 26.0 11.8 19.2 9.6 10.1 19.5 8.0 21.4 27.8 13.1 22.8 17.1 21.5 25.4 21.5 20.8 14.7 20.9 44.3 19.8 16.4 46.9 31.1 80.3 6.9 13.7 15.8 13.2 24.6 9.9 31.6 48.6 16.3 15.8 9.7 21.0 20.1 22.1 28.3 39.1 11.8 10.6 17.0 12.2 14.7 7.3 59.5 21.5 15.2 16.0 3.7 27.2 20.6 54.6 8.0 6.3 25.8 20.6 21.4 18.8 19.5 28.1 55.4 12.9 22.2 6.6 13.3 17.2 100.7 20.6 22.3 12.8 17.2 20.5 33.9 28.6 16.2 RRP1 "D21S2056E, NNP-1, Nop52, RRP1A" ENSG00000160214 "Ribosomal RNA processing 1" P56182 21 43789513-43805293 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016818, HPA018166" Approved Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" "HPA016818: AB_1854561, HPA018166: AB_1854562" "unprognostic (5.38e-2)" "unprognostic (3.48e-1)" "unprognostic (3.43e-1)" "unprognostic (2.53e-2)" "unprognostic (9.44e-2)" "unprognostic (1.13e-2)" "unprognostic (7.69e-3)" "unprognostic (1.26e-1)" "unprognostic (7.63e-3)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (6.29e-5)" "unprognostic (1.13e-1)" "unprognostic (9.21e-3)" "unprognostic (2.64e-1)" "unprognostic (1.88e-1)" 8.0 8.2 8.0 6.5 8.7 5.3 7.3 7.4 10.2 6.9 4.8 6.4 5.0 7.1 3.3 16.0 6.4 4.0 7.0 9.2 7.2 7.6 13.0 5.3 8.1 8.9 8.1 8.0 9.7 4.8 5.5 4.9 8.0 7.2 3.0 1.7 8.1 4.2 12.9 11.9 5.9 3.4 6.6 8.2 7.5 7.9 7.6 5.0 6.0 5.3 6.1 7.3 7.9 10.8 37.6 19.6 13.5 22.6 7.3 8.2 25.6 18.5 10.9 25.7 18.1 52.1 21.6 35.5 14.9 10.4 23.8 18.8 25.2 18.5 11.7 17.7 47.9 50.4 18.8 32.1 14.9 32.6 17.5 11.0 17.0 26.0 20.6 6.7 13.7 32.9 67.3 26.9 12.2 43.2 28.7 44.7 44.8 26.1 28.7 52.0 10.7 66.4 13.4 20.5 31.6 18.8 19.3 21.0 25.3 3.8 21.5 22.1 15.6 17.2 19.1 18.2 33.0 32.1 29.8 37.1 25.7 53.7 22.6 0.1 5.0 1.7 10.7 4.8 13.4 11.0 11.0 11.1 10.2 13.0 11.9 8.0 1.1 13.1 2.3 8.8 6.8 7.0 8.0 8.7 7.4 10.2 9.2 7.2 8.9 8.1 8.0 6.6 7.6 10.8 12.9 16.0 19.4 9.4 17.3 72.3 40.2 55.9 23.3 18.7 14.4 12.7 6.1 18.6 45.3 7.3 20.9 31.4 12.7 18.6 7.9 40.0 4.2 14.9 15.5 18.8 20.9 19.0 6.2 33.1 39.0 24.5 18.8 16.1 20.3 20.1 9.3 16.0 32.7 8.4 6.3 19.3 32.6 8.4 35.0 2.7 19.3 13.6 42.7 2.8 15.3 12.3 13.4 2.5 11.6 41.4 9.1 20.7 19.2 59.4 10.5 21.0 24.3 17.6 32.9 23.8 20.6 21.4 30.0 32.2 70.2 30.4 15.0 21.4 29.5 46.1 RSAD1 "FLJ11164, HemW" ENSG00000136444 "Radical S-adenosyl methionine domain containing 1" Q9HA92 17 50478860-50485974 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA022436, HPA022967, HPA024459" Approved Approved "Mitotic chromosome,Mitochondria" Yes NA "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Mitochondria "Mitotic chromosome" "HPA022436: AB_2180789, HPA022967: AB_1856484, HPA024459: " "unprognostic (8.21e-2)" "unprognostic (4.11e-3)" "unprognostic (3.72e-2)" "unprognostic (1.83e-2)" "unprognostic (3.49e-2)" "unprognostic (2.93e-2)" "unprognostic (6.01e-2)" "unprognostic (1.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.13e-2)" "prognostic favorable (5.04e-4)" "unprognostic (1.06e-1)" "unprognostic (1.65e-2)" "unprognostic (4.89e-2)" "unprognostic (2.95e-1)" "unprognostic (7.85e-2)" "unprognostic (3.22e-2)" 23.9 41.4 34.7 16.4 37.8 12.8 23.5 37.5 43.4 36.9 32.9 24.3 17.1 24.2 17.5 17.3 24.5 12.5 43.3 34.4 33.9 40.9 44.0 21.1 19.8 34.5 34.9 31.8 48.9 27.5 23.6 12.4 35.1 25.2 17.6 21.2 27.3 14.9 66.0 22.2 23.9 14.4 34.2 31.8 32.5 14.2 35.4 18.4 29.1 57.0 17.8 26.1 23.6 37.0 13.0 43.2 20.3 33.7 34.0 27.6 7.2 22.2 21.6 27.9 23.5 43.0 16.1 34.9 48.0 15.6 27.6 12.1 23.2 31.0 23.9 38.9 42.0 47.0 20.5 42.4 23.7 28.6 31.7 20.2 33.7 18.6 35.7 23.0 27.5 84.1 36.9 32.3 23.7 30.3 48.1 20.9 8.2 54.6 45.9 19.6 23.2 31.6 34.0 19.4 11.1 37.9 5.7 26.3 29.7 25.6 39.6 28.7 19.6 29.0 30.8 22.3 26.4 50.0 37.6 13.5 21.8 40.3 20.6 1.1 4.2 3.8 8.5 4.4 8.5 4.5 7.3 8.4 4.9 6.9 9.4 9.5 0.0 6.6 4.2 5.4 6.2 5.7 34.7 37.8 37.5 43.4 34.4 33.9 34.5 34.9 35.1 34.2 35.4 37.0 15.1 3.2 13.1 18.3 16.0 10.1 4.4 7.2 19.4 14.8 12.1 12.8 29.4 12.8 7.7 16.5 2.1 21.4 24.1 10.8 23.5 14.4 8.8 5.3 10.4 12.4 25.2 12.0 24.0 29.5 11.1 13.1 12.2 7.4 3.8 15.8 10.0 18.5 16.1 8.4 21.5 11.7 8.2 7.2 6.1 7.4 15.5 9.6 17.8 16.9 12.5 32.1 19.6 13.6 12.4 11.8 6.2 10.9 18.7 6.5 11.1 11.1 3.8 7.8 13.1 16.0 11.3 11.5 21.9 10.6 9.9 10.1 18.7 43.6 12.9 3.4 RXYLT1 "HP10481, TMEM5" ENSG00000118600 "Ribitol xylosyltransferase 1" Q9Y2B1 12 63779842-63809562 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transferase "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 37.2;Endometrial stromal cells: 34.5;Extravillous trophoblasts: 33.8;Syncytiotrophoblasts: 37.1;Theca cells: 45.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064014 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Golgi apparatus" "HPA064014: AB_2685176" "unprognostic (1.19e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (3.58e-1)" "unprognostic (1.33e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.47e-2)" "unprognostic (2.09e-3)" "unprognostic (3.17e-1)" "unprognostic (7.03e-2)" "unprognostic (1.39e-1)" "unprognostic (9.33e-2)" "unprognostic (5.27e-2)" "unprognostic (2.29e-2)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" 6.6 12.0 6.9 4.9 7.6 4.4 10.8 7.1 8.5 7.1 7.2 6.9 5.7 6.7 15.3 5.6 7.9 5.5 14.3 6.8 7.9 10.9 8.5 5.2 7.4 7.5 7.0 12.0 11.8 15.4 9.0 5.7 7.7 8.4 7.5 9.9 8.3 7.0 10.7 8.3 4.2 6.1 7.5 5.7 5.5 11.8 7.3 7.3 12.8 8.7 7.2 7.4 5.5 9.3 9.6 19.9 14.2 11.7 12.2 16.4 13.5 10.4 18.5 17.7 11.9 6.6 10.1 20.5 17.7 13.4 14.2 9.3 17.5 16.0 22.3 18.5 13.4 11.5 5.1 12.2 18.1 17.6 10.0 14.6 15.6 17.1 22.6 16.8 10.4 16.5 14.0 19.8 27.8 18.3 10.2 8.1 8.1 10.4 20.6 9.0 14.8 13.1 17.8 15.1 30.7 5.9 10.4 9.5 24.5 9.0 20.2 9.9 10.1 14.9 15.2 9.7 15.4 10.6 17.9 15.6 10.9 11.4 20.9 0.8 1.7 1.0 1.9 1.6 3.5 3.0 2.4 2.6 1.7 2.2 2.8 2.6 0.3 3.0 2.2 4.1 4.3 1.2 6.9 7.6 7.1 8.5 6.8 7.9 7.5 7.0 7.7 7.5 7.3 9.3 17.5 9.6 8.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 26.8 26.8 0.0 0.0 10.5 16.5 0.0 24.7 6.9 0.0 37.2 23.1 0.0 28.6 34.5 8.1 0.0 0.0 0.0 30.7 33.8 12.1 0.0 16.6 7.6 15.5 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 8.3 0.0 0.0 0.0 0.0 17.3 0.0 0.0 2.4 0.0 0.0 30.3 13.8 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 37.1 4.8 45.0 0.0 0.0 S100A1 "S100-alpha, S100A" ENSG00000160678 "S100 calcium binding protein A1" P23297 1 153627926-153632039 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 3076.8;skeletal muscle: 3060.2;tongue: 4911.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 1848.3" "Group enriched" "Detected in all" 5 "melanoma: 210.5;ovarian cancer: 110.1;thyroid cancer: 123.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Hep G2: 325.8;SK-MEL-30: 1130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002599, HPA006462" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 290000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nucleoplasm, Golgi apparatus" "CAB002599: AB_2315307, HPA006462: AB_1079857" "unprognostic (6.13e-2)" "unprognostic (7.60e-2)" "unprognostic (5.96e-5)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.19e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (2.34e-3)" "unprognostic (6.83e-3)" "unprognostic (5.22e-1)" "unprognostic (5.04e-3)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.68e-1)" "unprognostic (4.56e-2)" "unprognostic (2.70e-3)" "unprognostic (9.74e-4)" 179.7 8.3 811.3 6.5 898.6 2.3 77.2 851.4 952.4 2.9 643.9 14.5 11.1 4.2 1.0 81.0 41.8 4.9 3076.8 779.4 813.6 194.9 4.5 3.9 5.1 907.6 894.8 2.0 16.8 160.9 54.6 18.1 871.2 29.0 1.2 36.5 622.1 9.3 3060.2 23.0 6.9 1.6 847.7 4.2 23.1 5.9 882.9 9.4 167.9 4911.5 4.0 4.3 2.9 967.6 6.0 3.4 3.9 33.7 0.5 0.2 2.9 7.7 0.2 0.6 0.2 6.6 3.4 3.7 137.7 0.6 2.7 10.3 0.3 0.4 0.0 4.2 3.3 8.2 5.4 325.8 0.4 3.0 2.3 0.7 0.0 0.0 0.1 7.9 0.0 1.5 27.2 3.7 0.1 10.6 1.2 4.9 1.8 4.3 2.6 22.5 3.3 8.0 6.0 12.1 6.1 1.9 3.5 10.6 1130.2 11.1 32.8 16.2 2.7 3.3 2.8 3.0 3.8 6.1 5.7 6.2 2.5 6.2 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 811.3 898.6 851.4 952.4 779.4 813.6 907.6 894.8 871.2 847.7 882.9 967.6 4.3 0.0 0.0 59.4 9.5 9.7 1.2 0.4 1.8 1.1 369.9 354.1 74.4 8.6 0.2 154.5 2.1 1.1 5.9 1.1 162.4 0.9 0.6 90.5 17.3 5.3 1.8 0.0 0.3 3.7 1.9 6.0 0.0 193.3 0.0 0.0 7.9 4.7 199.1 0.0 0.3 3.7 0.0 0.6 3.5 2.2 6.5 15.6 341.5 2.8 0.0 163.5 0.0 2.0 45.8 1.9 0.6 9.1 0.0 1.8 0.9 1848.3 0.2 2.7 0.0 67.0 4.2 3.8 2.8 1.0 2.3 3.4 8.2 2.3 1.8 0.7 S100A13 ENSG00000189171 "S100 calcium binding protein A13" Q99584 1 153618787-153631360 "Predicted intracellular proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 3084.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 28.3" "Group enriched" "Detected in all" 5 "dendritic cells: 11.9;NK-cells: 28.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 811.3;SuSa: 896.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019592, CAB025494" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 36000 "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "CAB025494: , HPA019592: AB_10601499" "unprognostic (1.50e-2)" "unprognostic (9.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (7.77e-2)" "unprognostic (9.72e-3)" "unprognostic (1.75e-3)" "unprognostic (9.93e-2)" "unprognostic (6.48e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.83e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-2)" 275.3 137.3 237.4 47.7 247.3 4.4 222.4 241.0 347.5 133.7 214.6 198.9 30.6 111.8 72.1 91.7 129.8 103.9 310.1 233.1 240.8 262.2 66.2 138.0 48.8 252.9 245.5 138.2 75.7 317.4 73.9 70.1 249.4 100.9 59.8 25.8 156.1 64.6 250.6 114.0 116.5 68.9 245.8 111.7 94.4 41.2 251.6 21.2 318.7 220.6 49.6 121.2 122.7 258.6 188.7 153.7 174.5 111.4 150.7 437.5 62.7 254.7 400.0 150.6 172.2 150.4 203.7 4.9 471.6 435.5 22.3 174.7 73.5 158.7 132.7 0.8 68.1 12.0 178.0 129.6 99.8 5.9 39.2 355.3 59.4 135.3 145.0 441.9 346.5 1.3 61.4 0.3 475.2 663.4 0.4 3.4 141.0 161.1 460.2 30.0 180.4 1.4 811.3 141.9 53.4 2.0 544.7 277.2 576.7 896.9 226.4 6.8 495.0 103.3 57.9 139.5 312.0 2.0 5.3 9.3 185.5 3.2 62.1 4.1 2.0 0.2 0.4 0.9 0.9 4.1 0.4 0.3 7.0 2.0 0.6 0.5 0.3 28.3 1.4 11.9 1.4 1.1 237.4 247.3 241.0 347.5 233.1 240.8 252.9 245.5 249.4 245.8 251.6 258.6 331.0 28.9 106.1 29.7 9.3 110.5 177.4 105.0 103.0 2.1 311.2 345.6 141.9 164.5 104.0 465.3 0.0 132.4 15.3 148.7 248.4 323.3 8.4 399.3 449.1 251.9 124.7 17.3 1.2 323.6 202.1 450.0 58.6 573.8 23.5 185.5 372.3 51.8 162.3 0.0 0.5 167.5 61.1 31.7 107.7 36.3 771.7 37.1 238.3 13.1 14.8 308.1 1.0 0.0 8.8 488.4 164.7 314.1 6.3 240.0 128.7 521.7 77.1 6.9 0.0 234.2 132.5 12.8 23.4 80.3 75.7 74.7 20.5 3084.7 100.6 244.3 SAP18 "2HOR0202, MGC27131, SAP18p" ENSG00000150459 "Sin3A associated protein 18" O00422 13 21140514-21149084 "Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011352, CAB012273" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies" Cytosol "CAB012273: , HPA011352: AB_1856563" "unprognostic (5.08e-2)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-3)" "unprognostic (2.84e-1)" "unprognostic (5.21e-2)" "unprognostic (3.02e-1)" "unprognostic (3.18e-1)" "unprognostic (8.15e-2)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (4.14e-2)" "unprognostic (2.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.70e-2)" "unprognostic (3.70e-3)" "unprognostic (2.78e-2)" 125.7 164.3 140.9 122.9 152.2 242.3 121.6 149.6 198.9 120.4 137.8 141.8 137.4 123.8 97.5 159.2 112.9 82.4 195.8 147.4 160.7 190.4 171.1 106.5 118.0 154.7 153.8 109.5 134.6 114.2 129.6 111.7 157.7 109.7 58.5 89.5 126.3 73.0 297.9 119.5 127.5 51.7 164.1 107.6 119.5 194.3 155.7 115.5 110.7 156.3 64.8 131.7 118.5 170.7 182.1 99.3 159.5 173.1 169.0 140.5 246.9 227.1 167.2 205.5 151.3 181.1 342.4 187.3 272.0 189.1 223.4 186.5 198.1 142.4 231.5 288.0 100.4 267.6 121.2 305.9 191.8 367.1 207.5 143.0 159.7 157.5 187.1 158.4 157.3 223.1 128.8 103.6 188.2 231.0 417.0 599.0 200.7 501.5 109.7 261.1 251.4 187.1 295.7 160.7 185.0 161.1 145.7 213.8 296.5 176.5 206.8 528.0 192.6 126.0 141.9 230.1 268.9 159.6 243.6 536.7 122.5 214.9 236.4 433.0 431.5 540.0 344.1 485.0 349.3 493.7 418.2 410.9 427.8 443.6 405.9 402.9 430.5 395.3 547.4 568.8 517.5 909.3 140.9 152.2 149.6 198.9 147.4 160.7 154.7 153.8 157.7 164.1 155.7 170.7 638.0 134.6 143.5 15.0 291.7 458.6 336.3 640.9 310.7 101.5 298.9 594.9 592.9 194.5 383.8 233.6 41.7 566.2 397.4 353.6 759.2 396.5 1259.5 334.1 231.1 273.1 234.5 214.4 20.8 365.6 528.0 374.0 170.2 256.2 258.6 176.6 180.2 242.0 396.0 119.5 23.4 364.5 468.0 189.5 440.9 206.0 342.3 260.4 407.4 17.8 385.0 370.8 233.8 19.6 26.2 401.9 417.6 303.6 182.3 325.9 475.0 1100.6 446.8 132.3 203.8 362.5 438.3 547.7 319.9 271.7 422.2 908.3 338.8 254.2 344.7 419.9 SDHAF4 "C6orf57, Sdh8" ENSG00000154079 "Succinate dehydrogenase complex assembly factor 4" Q5VUM1 6 70566917-70589569 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031824 Supported Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "HPA031824: AB_10602113" "unprognostic (8.72e-2)" "unprognostic (1.64e-1)" "unprognostic (4.95e-2)" "unprognostic (9.96e-2)" "unprognostic (4.58e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (1.42e-3)" "unprognostic (3.18e-2)" "unprognostic (3.17e-1)" "prognostic favorable (1.95e-5)" "unprognostic (2.45e-2)" "unprognostic (9.37e-2)" "unprognostic (3.05e-1)" "unprognostic (9.94e-2)" 11.2 12.3 7.1 4.2 7.5 4.3 10.5 6.8 10.5 6.6 7.3 6.8 5.0 5.8 9.3 7.5 10.3 4.2 14.5 7.6 9.4 12.5 8.5 5.4 6.0 6.9 6.3 6.4 6.6 14.4 12.7 6.8 7.3 7.6 6.7 10.0 8.7 5.4 23.6 8.6 5.4 4.2 5.8 5.6 7.0 5.3 7.8 6.4 7.3 10.6 5.2 6.8 6.7 7.6 13.3 4.2 18.8 11.6 9.0 13.6 3.5 7.1 5.1 3.4 5.0 3.8 11.3 9.1 12.7 3.8 8.0 2.3 6.2 5.9 5.2 18.3 4.3 6.6 1.8 3.9 15.3 6.3 5.1 9.6 19.3 2.6 14.8 11.6 8.0 14.8 4.2 13.9 11.0 9.0 5.9 15.7 8.8 6.5 4.5 6.4 12.6 10.8 14.9 4.4 16.8 12.1 4.3 2.1 9.6 8.0 9.6 16.5 6.3 3.5 2.7 2.8 7.7 6.2 4.5 3.1 3.9 15.1 8.5 4.0 4.6 4.4 3.4 4.3 3.3 3.7 3.7 4.1 5.1 4.7 3.9 3.8 3.3 4.7 4.6 6.2 4.2 3.0 7.1 7.5 6.8 10.5 7.6 9.4 6.9 6.3 7.3 5.8 7.8 7.6 5.4 12.8 13.9 4.9 3.3 0.0 7.9 0.0 3.4 7.4 6.5 7.5 21.3 10.0 5.6 7.3 8.4 10.5 5.0 2.9 23.5 9.1 5.5 20.2 8.2 5.0 3.6 2.5 7.7 11.6 8.5 6.6 2.6 6.0 5.1 6.1 4.2 11.8 10.0 18.5 7.5 5.8 0.0 5.3 0.0 2.5 12.5 6.2 0.0 2.8 10.1 10.1 3.1 12.1 7.7 13.2 5.3 6.8 2.2 9.5 6.2 16.8 13.8 6.4 13.1 5.1 4.9 10.0 6.1 5.7 0.0 5.1 3.9 6.1 5.3 8.0 SDR39U1 "C14orf124, HCDI" ENSG00000100445 "Short chain dehydrogenase/reductase family 39U member 1" Q9NRG7 14 24439766-24442905 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044294, HPA075356" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "HPA044294: AB_10961400, HPA075356: " "unprognostic (2.99e-2)" "unprognostic (1.21e-1)" "unprognostic (4.13e-2)" "unprognostic (2.42e-2)" "unprognostic (2.36e-1)" "unprognostic (6.28e-2)" "unprognostic (2.06e-2)" "unprognostic (1.67e-3)" "unprognostic (4.24e-1)" "unprognostic (2.87e-3)" "prognostic favorable (2.34e-4)" "unprognostic (9.13e-2)" "unprognostic (1.13e-3)" "unprognostic (7.47e-2)" "unprognostic (2.48e-1)" "unprognostic (1.63e-1)" "unprognostic (5.32e-2)" 41.5 73.9 55.4 14.8 56.9 28.9 44.6 59.7 65.1 40.4 53.4 43.3 16.9 33.5 17.7 35.1 35.8 11.6 83.7 54.0 55.7 60.2 57.9 35.1 22.6 56.7 57.9 47.2 50.1 22.7 58.1 14.4 56.6 47.2 9.3 37.9 38.0 23.1 96.7 40.1 42.1 11.6 57.4 57.7 47.5 34.7 58.5 27.8 38.7 72.5 14.1 41.1 33.4 57.3 20.1 35.4 25.5 30.0 34.8 26.5 24.4 11.5 16.3 26.4 30.2 27.4 26.0 28.4 30.0 13.4 19.6 37.1 22.8 29.2 11.5 38.2 39.5 25.3 26.1 74.1 16.9 23.7 23.4 29.7 34.6 19.0 27.2 26.9 28.5 65.5 23.1 24.5 26.3 36.2 40.2 39.2 24.1 31.3 32.6 50.9 13.2 20.9 47.5 27.1 43.8 36.8 30.3 55.4 28.3 15.1 38.1 34.9 14.2 8.0 25.5 23.7 15.3 38.3 26.9 35.7 21.1 30.6 21.2 39.1 38.3 23.8 40.3 23.7 39.2 49.7 30.7 32.3 43.7 49.7 43.2 45.2 11.4 58.4 20.3 60.7 40.2 33.0 55.4 56.9 59.7 65.1 54.0 55.7 56.7 57.9 56.6 57.4 58.5 57.3 34.9 28.9 21.7 10.1 35.0 26.5 40.8 40.1 21.6 37.2 44.2 47.2 0.2 45.8 36.5 40.5 12.5 48.4 41.6 19.7 121.3 29.1 16.9 16.9 15.9 27.3 27.6 35.3 12.2 19.9 24.3 24.8 13.3 17.8 36.1 28.4 21.0 38.6 30.2 28.6 12.6 25.8 38.7 19.3 19.6 26.3 32.9 21.6 42.7 12.2 22.9 63.4 37.0 11.1 17.0 15.7 17.7 31.6 34.4 24.9 21.3 71.7 26.8 47.4 0.0 25.5 24.0 67.1 22.6 21.0 27.3 56.1 28.6 27.0 22.5 29.8 SEH1L "SEC13L, Seh1, SEH1A, SEH1B" ENSG00000085415 "SEH1 like nucleoporin" Q96EE3 18 12947133-12987536 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039964 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA039964: AB_10795241" "unprognostic (5.14e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (7.97e-2)" "unprognostic (1.87e-2)" "unprognostic (1.13e-3)" "unprognostic (7.14e-2)" "unprognostic (1.93e-2)" "unprognostic (1.45e-3)" "unprognostic (7.12e-2)" "unprognostic (8.06e-2)" "unprognostic (3.81e-3)" "unprognostic (5.91e-2)" "unprognostic (3.01e-1)" "unprognostic (2.67e-1)" "unprognostic (7.05e-2)" 17.4 12.0 15.8 16.5 17.0 12.8 14.5 14.8 22.9 12.5 12.5 15.0 11.6 13.7 12.2 19.7 12.1 9.8 15.6 19.8 18.3 14.9 22.4 12.3 19.8 12.2 12.1 12.1 15.1 10.7 14.2 12.6 12.7 11.1 13.9 6.5 11.9 9.1 37.3 15.8 12.0 13.4 13.4 13.2 12.0 15.0 16.6 23.8 12.5 26.9 21.5 19.2 13.2 17.8 53.6 40.6 30.9 49.2 21.2 31.5 45.1 45.5 46.3 52.3 59.8 104.7 27.5 114.8 54.0 53.1 46.8 26.6 72.8 52.0 67.5 31.9 46.8 71.6 38.4 62.3 47.7 197.0 45.4 22.5 40.1 60.6 88.8 21.8 27.7 51.6 98.1 41.5 42.9 57.9 106.3 84.4 39.2 215.5 41.9 70.6 71.8 74.6 40.6 53.4 59.8 35.7 58.2 43.7 47.9 22.3 27.3 64.7 22.4 53.5 123.6 81.4 80.7 30.6 48.1 122.1 35.1 70.1 35.0 4.1 23.5 5.6 14.0 31.6 18.5 23.7 16.3 17.0 37.8 23.9 20.9 18.0 2.6 23.6 26.4 20.6 12.2 22.6 15.8 17.0 14.8 22.9 19.8 18.3 12.2 12.1 12.7 13.4 16.6 17.8 13.1 6.4 20.2 8.5 26.5 54.7 47.0 24.6 40.9 8.0 16.3 12.8 14.0 14.3 18.3 12.9 12.5 23.6 16.1 12.9 9.8 15.0 9.2 18.5 19.2 19.3 19.2 26.1 15.3 13.3 31.8 17.9 15.8 27.6 7.6 17.8 13.2 21.6 21.3 3.3 10.1 20.3 14.2 13.2 20.4 11.4 9.3 19.7 16.0 12.2 16.9 5.8 7.2 6.0 13.3 16.0 15.3 10.9 23.9 46.7 11.5 16.5 8.5 10.1 13.1 26.8 22.3 16.9 14.0 41.6 59.8 23.7 16.0 19.6 24.9 43.0 SELENOK SELK ENSG00000113811 "Selenoprotein K" Q9Y6D0 3 53884417-53891962 "Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 373.5;Proximal tubular cells: 415.0;Syncytiotrophoblasts: 350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 471.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 471.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA008196 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "HPA008196: AB_1856665" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (3.85e-1)" "prognostic favorable (7.18e-4)" "unprognostic (9.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.02e-2)" "prognostic favorable (3.76e-4)" "unprognostic (2.75e-1)" "unprognostic (5.21e-2)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" "unprognostic (3.40e-2)" "unprognostic (8.43e-2)" "unprognostic (8.12e-2)" "unprognostic (9.35e-2)" "unprognostic (2.56e-3)" 39.6 51.9 52.3 27.0 53.0 70.1 35.8 55.2 67.9 29.8 52.3 35.9 23.3 29.1 64.4 27.8 33.9 23.4 90.1 52.0 55.8 42.1 74.2 38.3 23.7 55.0 53.7 48.6 51.7 55.7 62.8 26.5 55.5 34.6 29.3 86.5 29.7 28.5 86.7 24.1 30.4 18.7 55.7 32.3 39.6 32.0 53.3 26.7 43.0 61.2 29.4 35.5 26.1 58.4 22.4 14.9 34.3 23.3 52.1 32.8 36.8 32.0 40.5 43.4 48.9 33.4 33.1 33.8 13.8 23.4 48.7 13.8 40.7 24.5 37.8 59.6 50.3 21.1 61.4 77.6 49.1 28.3 48.6 19.8 40.3 30.1 39.4 25.2 35.3 25.1 20.1 86.3 38.5 24.7 18.5 33.5 33.4 27.5 55.1 11.5 20.9 61.9 51.3 37.1 17.5 49.5 21.9 29.4 32.7 37.5 19.6 44.0 20.6 24.4 28.7 62.2 45.7 62.8 76.3 31.4 36.8 37.3 38.2 471.4 41.7 110.7 69.5 47.2 67.5 60.3 63.0 70.0 36.6 49.0 55.0 63.0 94.1 52.2 56.6 66.3 72.1 82.6 52.3 53.0 55.2 67.9 52.0 55.8 55.0 53.7 55.5 55.7 53.3 58.4 223.1 134.6 103.9 0.0 173.5 0.0 0.0 0.0 0.0 0.0 233.7 237.5 0.0 0.0 53.9 149.0 0.0 162.3 373.5 0.0 189.8 258.5 0.0 150.1 113.5 62.7 0.0 0.0 0.0 199.6 239.6 86.9 0.0 237.9 237.1 59.1 0.0 0.0 162.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.6 0.0 0.0 74.9 0.0 0.0 0.0 0.0 282.5 0.0 0.0 110.6 0.0 0.0 415.0 53.9 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.0 350.1 155.9 94.7 0.0 0.0 SGCB "A3b, LGMD2E, SGC" ENSG00000163069 "Sarcoglycan beta" Q16585 4 52020706-52038299 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 105.7" "Cell type enhanced" "Detected in many" "Late spermatids: 203.7" "Cancer enhanced" "Detected in all" "glioma: 56.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 104.7" "Low region specificity" "Detected in all" "HPA011422, HPA058656" Enhanced Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA011422: AB_1856795, HPA058656: AB_2683790" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (1.03e-1)" "unprognostic (1.60e-3)" "unprognostic (9.80e-2)" "unprognostic (3.42e-2)" "unprognostic (3.57e-3)" "unprognostic (1.86e-2)" "unprognostic (2.84e-2)" "unprognostic (6.04e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.53e-6)" "unprognostic (3.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (7.61e-4)" 32.7 21.6 27.1 9.5 30.3 0.5 14.7 28.0 32.2 23.4 21.4 32.9 13.1 28.1 11.1 21.9 20.5 19.5 57.2 25.3 27.7 35.0 10.8 15.2 6.1 29.7 28.4 20.1 6.5 47.0 13.9 24.2 30.3 25.0 16.2 16.6 13.5 27.2 105.7 7.2 14.9 37.3 29.0 11.1 14.0 16.0 28.3 5.6 9.2 81.3 4.5 20.4 15.7 33.4 11.4 13.7 27.8 10.6 104.7 78.5 10.1 62.8 79.9 34.5 36.2 3.7 14.9 3.0 11.8 82.9 53.5 5.5 20.9 23.1 36.7 18.8 7.8 0.2 11.8 6.8 42.8 6.8 3.6 86.8 15.9 29.9 17.3 89.8 46.1 10.7 0.1 0.1 74.5 4.4 15.1 0.1 10.0 4.6 20.4 0.0 14.8 0.2 29.2 3.8 16.2 28.4 39.9 1.9 14.1 31.0 5.2 4.1 47.0 50.8 17.0 24.1 56.6 14.9 20.4 5.5 37.5 2.4 59.7 0.3 1.0 0.0 2.1 0.5 2.1 2.6 2.5 2.3 0.5 2.3 1.7 2.2 0.5 0.3 0.4 1.0 4.2 1.0 27.1 30.3 28.0 32.2 25.3 27.7 29.7 28.4 30.3 29.0 28.3 33.4 38.9 32.1 13.1 15.3 6.6 13.4 25.8 70.2 9.6 22.0 8.6 19.7 88.8 25.8 19.6 12.9 6.2 5.7 2.8 15.6 1.9 28.7 61.1 32.6 48.1 27.2 16.3 0.0 17.3 51.8 49.8 64.6 12.8 29.7 2.5 16.7 36.0 15.7 2.8 28.6 21.2 4.2 8.2 2.1 8.7 203.7 38.8 2.7 26.6 24.4 1.9 23.6 1.0 38.7 38.1 53.8 6.0 91.4 4.6 11.7 32.6 64.6 20.4 16.5 46.0 102.8 59.8 12.2 17.4 8.0 10.5 6.3 7.3 14.2 15.1 13.5 SGTA SGT ENSG00000104969 "Small glutamine rich tetratricopeptide repeat containing alpha" O43765 19 2754715-2783362 "Predicted intracellular proteins" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056309 Approved Approved Nucleoplasm NA NA 81000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA056309: AB_2683096" "unprognostic (2.31e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.13e-1)" "prognostic favorable (1.04e-4)" "unprognostic (7.99e-2)" "unprognostic (1.06e-1)" "unprognostic (2.52e-3)" "unprognostic (1.47e-1)" "unprognostic (7.23e-2)" "unprognostic (1.97e-1)" "unprognostic (7.58e-3)" "unprognostic (2.89e-2)" "prognostic favorable (2.35e-4)" "unprognostic (1.87e-2)" "unprognostic (1.23e-1)" "unprognostic (4.04e-1)" "unprognostic (3.04e-1)" 38.4 46.4 60.2 16.8 61.7 29.0 39.8 61.4 76.0 40.8 45.4 53.4 27.3 44.2 18.6 53.3 42.0 13.8 91.0 60.1 57.6 54.7 72.3 37.5 19.9 64.9 62.9 52.8 57.8 22.1 56.5 22.0 60.4 51.1 9.3 17.2 36.2 18.6 110.8 40.2 37.6 14.9 61.7 49.2 47.7 54.1 61.3 31.6 47.9 43.4 13.2 43.7 38.1 66.5 67.9 58.8 57.4 56.5 21.7 23.9 45.9 46.8 35.7 71.3 60.8 95.4 31.4 61.5 37.7 39.4 44.4 53.3 70.2 79.5 24.6 0.0 59.3 37.8 25.0 81.8 56.0 49.0 46.5 39.1 39.2 58.5 45.6 27.5 51.5 60.5 95.6 57.6 38.3 46.4 87.8 70.8 98.2 51.6 57.3 113.8 43.7 80.8 48.0 43.0 104.2 85.6 31.6 61.0 73.4 21.5 66.8 76.0 41.0 50.7 53.2 91.3 86.8 101.1 88.1 82.6 65.6 122.2 81.1 17.3 21.4 20.9 17.4 28.1 20.4 15.4 19.0 19.1 23.6 13.9 14.4 14.4 20.7 21.2 27.8 20.5 25.4 21.8 60.2 61.7 61.4 76.0 60.1 57.6 64.9 62.9 60.4 61.7 61.3 66.5 31.6 9.6 15.7 15.3 26.3 23.7 24.0 21.2 17.1 42.3 32.5 30.4 46.8 12.8 14.9 18.4 25.0 52.2 19.3 54.1 35.2 40.0 65.4 26.1 21.9 26.9 32.2 16.6 9.8 45.1 56.5 25.8 30.5 31.0 28.5 34.4 17.5 24.8 37.4 38.7 9.6 36.3 26.4 22.0 23.6 49.8 22.1 26.2 19.6 4.7 30.3 42.9 17.5 10.6 34.2 40.5 38.2 27.4 24.9 27.4 36.1 27.5 10.6 48.8 13.1 26.6 25.9 39.3 21.6 23.2 24.6 92.8 19.9 31.5 46.2 29.7 SIRT3 SIR2L3 ENSG00000142082 "Sirtuin 3" Q9NTG7 11 215030-236931 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026809, CAB037142" Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "CAB037142: AB_1079982, HPA026809: AB_10601160" "unprognostic (1.76e-2)" "unprognostic (2.69e-1)" "unprognostic (2.04e-1)" "prognostic favorable (8.51e-5)" "unprognostic (1.52e-3)" "unprognostic (2.65e-1)" "unprognostic (3.45e-2)" "unprognostic (5.52e-2)" "unprognostic (8.64e-2)" "unprognostic (1.31e-1)" "prognostic favorable (4.45e-4)" "unprognostic (2.06e-1)" "prognostic favorable (4.85e-9)" "unprognostic (1.04e-1)" "unprognostic (5.53e-2)" "unprognostic (3.45e-1)" "unprognostic (3.75e-2)" 11.1 13.8 24.5 10.4 28.8 11.8 18.6 19.7 28.8 14.3 26.1 13.9 13.3 12.6 40.1 9.9 14.4 7.6 24.4 25.1 20.8 17.2 25.8 10.3 13.8 19.0 20.4 18.3 18.0 11.2 28.0 5.8 18.4 16.7 14.2 26.8 12.6 12.4 27.3 20.2 14.6 9.7 19.0 14.7 13.5 25.2 21.6 6.8 15.7 19.9 14.9 11.5 11.1 24.0 9.7 11.1 16.7 17.7 19.1 24.1 8.0 13.6 11.0 10.1 7.9 11.5 22.8 5.9 6.2 8.5 9.8 18.6 8.2 7.4 9.8 11.2 12.7 7.4 15.7 12.6 8.4 9.7 17.3 17.8 14.1 10.2 10.9 17.3 6.7 11.1 15.3 11.0 4.6 10.8 4.0 15.0 7.5 8.5 13.2 10.8 13.2 9.8 10.2 6.6 9.3 7.5 11.5 16.7 6.4 10.8 11.9 2.2 9.3 11.4 5.4 3.2 4.1 19.4 17.3 8.4 12.4 7.7 5.9 0.1 3.1 3.1 3.6 2.5 3.8 5.3 3.3 4.1 2.8 4.3 6.0 4.9 3.1 8.1 6.6 4.8 4.0 2.7 24.5 28.8 19.7 28.8 25.1 20.8 19.0 20.4 18.4 19.0 21.6 24.0 6.0 3.2 6.5 17.0 10.4 5.0 7.0 13.1 12.5 7.4 16.0 15.5 23.4 14.3 7.4 5.5 8.4 12.6 7.2 7.2 33.2 7.5 22.0 7.4 5.8 6.7 6.0 14.3 19.2 5.8 10.3 8.6 11.7 4.6 10.2 8.4 7.5 18.3 8.8 10.1 18.3 8.1 10.2 5.5 3.3 21.0 9.0 6.4 10.6 8.4 3.5 13.5 5.2 9.0 11.6 5.1 9.3 9.1 14.6 5.5 14.3 18.9 9.0 9.5 0.0 7.3 6.5 25.5 9.6 9.9 4.1 6.8 8.4 14.2 11.2 4.0 SIRT5 ENSG00000124523 "Sirtuin 5" Q9NXA8 6 13574227-13615158 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.5;Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021798, HPA022002, HPA022992" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA021798: AB_1856911, HPA022002: AB_1856913, HPA022992: AB_1856915" "unprognostic (8.53e-2)" "unprognostic (7.79e-2)" "unprognostic (4.71e-2)" "unprognostic (5.26e-3)" "unprognostic (6.19e-2)" "unprognostic (1.63e-1)" "unprognostic (8.72e-2)" "unprognostic (1.38e-1)" "unprognostic (8.54e-3)" "unprognostic (2.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "prognostic favorable (8.76e-10)" "unprognostic (2.39e-1)" "unprognostic (6.88e-2)" "unprognostic (6.86e-2)" "unprognostic (2.36e-3)" 7.2 6.0 9.4 5.2 10.6 5.8 6.6 10.4 12.2 5.4 13.5 8.1 7.7 6.1 5.6 5.6 9.2 5.2 28.6 10.5 10.6 11.5 33.5 5.4 8.3 9.2 9.6 10.1 6.7 16.2 7.3 5.6 9.9 6.4 8.7 6.1 10.6 6.8 33.4 7.9 9.8 5.9 8.4 9.6 8.2 6.8 10.9 8.2 9.0 38.0 7.2 6.0 5.4 11.1 10.5 8.9 8.1 10.4 5.7 8.9 7.6 5.1 5.3 6.1 8.0 12.9 11.1 14.1 35.7 4.3 10.9 16.9 7.4 11.1 7.6 5.9 10.3 8.5 5.6 20.5 11.0 6.7 6.7 7.8 19.9 4.5 19.9 12.7 10.3 20.3 13.8 4.6 6.5 12.3 8.2 13.2 7.7 16.9 13.7 15.4 4.4 24.4 10.3 11.0 13.7 4.5 4.3 7.9 25.9 25.0 11.6 4.9 8.6 6.6 3.4 4.2 5.8 11.6 15.4 10.7 4.5 7.3 8.4 0.7 6.0 16.7 9.9 9.2 10.7 14.0 13.0 9.5 6.3 12.7 11.8 10.8 2.6 11.8 17.3 5.9 10.7 7.9 9.4 10.6 10.4 12.2 10.5 10.6 9.2 9.6 9.9 8.4 10.9 11.1 16.6 28.9 3.2 30.0 8.2 4.1 11.4 14.9 10.8 7.3 9.7 9.9 52.5 15.7 16.8 11.0 0.0 20.5 6.6 9.4 52.8 13.0 2.9 13.1 5.4 12.3 6.1 15.8 36.6 6.7 10.5 6.7 6.6 8.1 0.0 23.5 9.7 25.7 9.4 1.7 39.2 13.2 8.2 13.9 3.8 2.0 8.1 8.4 5.4 14.0 6.3 11.6 10.3 15.1 25.8 7.2 13.4 5.7 4.7 6.2 18.1 34.1 22.5 7.2 0.0 9.8 6.6 8.5 12.0 9.8 4.5 10.7 7.9 13.2 15.0 9.0 SKP1 "EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L" ENSG00000113558 "S-phase kinase associated protein 1" P63208 5 134148935-134176964 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012982, HPA053745, HPA058134" Approved Supported Nucleoplasm,Cytosol No No 880000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "CAB012982: AB_2533076, HPA053745: AB_2682245, HPA058134: AB_2683617" "prognostic unfavorable (7.53e-4)" "unprognostic (1.97e-1)" "unprognostic (9.81e-3)" "unprognostic (1.07e-1)" "unprognostic (2.02e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (4.47e-2)" "unprognostic (1.33e-1)" "unprognostic (1.72e-1)" "unprognostic (2.73e-1)" "unprognostic (3.07e-1)" "prognostic favorable (5.20e-4)" "unprognostic (1.02e-2)" "unprognostic (2.06e-1)" "unprognostic (8.26e-2)" "unprognostic (2.40e-1)" 430.5 566.7 442.5 194.9 463.6 363.7 559.0 471.7 648.6 455.4 486.2 529.3 230.1 441.3 490.7 401.9 437.8 330.1 650.5 470.8 492.5 588.6 442.8 346.6 305.9 465.9 457.1 525.4 266.6 776.2 501.0 394.6 474.2 420.9 350.2 484.3 366.9 550.9 1056.8 419.5 354.9 422.6 494.4 304.8 385.9 380.4 470.5 456.1 551.5 814.1 332.0 452.9 391.6 515.0 657.0 500.1 730.3 986.5 1103.6 891.8 519.2 744.6 939.1 854.0 877.1 773.0 620.0 481.9 1084.9 1009.8 974.9 356.6 738.2 1124.1 988.3 442.6 519.5 380.7 724.0 555.8 518.7 296.3 452.0 771.1 886.2 750.1 588.7 1060.4 928.4 611.2 467.4 411.8 1295.2 515.6 642.0 314.8 423.9 619.6 530.7 349.2 780.7 591.7 952.3 724.6 594.6 463.8 1010.2 254.4 726.9 942.4 738.5 454.6 705.3 547.5 338.4 578.2 766.4 254.7 459.1 717.8 762.3 555.5 608.0 1745.5 851.4 1484.9 884.6 841.7 1011.4 1202.8 1264.6 1099.9 817.8 1094.4 1495.5 1174.8 811.4 1096.1 1027.0 728.1 1416.7 2538.6 442.5 463.6 471.7 648.6 470.8 492.5 465.9 457.1 474.2 494.4 470.5 515.0 430.1 285.2 306.3 64.0 403.6 674.3 1025.7 1354.7 380.1 230.0 539.8 558.4 700.9 497.6 767.4 594.1 73.0 881.0 417.7 441.8 1696.3 644.9 593.3 511.9 405.3 410.1 356.0 617.8 66.5 376.9 749.4 561.5 270.1 439.0 336.9 433.9 340.2 376.9 471.6 223.8 65.8 402.2 1192.2 296.1 505.1 1048.6 601.4 344.8 718.6 33.7 565.4 792.8 338.8 43.7 87.0 378.1 564.0 712.8 278.2 744.7 630.0 1577.8 965.7 217.5 506.2 480.4 668.1 753.5 652.7 349.0 645.6 1347.0 511.1 500.4 410.4 837.6 SLC16A1 "MCT, MCT1" ENSG00000155380 "Solute carrier family 16 member 1" P53985 1 112911847-112957593 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 158.4;Granulosa cells: 322.8;Muller glia cells: 184.8;Rod photoreceptor cells: 277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003324, CAB017489, HPA071055, CAB079035" Enhanced Supported Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017489: AB_2189197, CAB079035: , HPA003324: AB_1856982, HPA071055: AB_2686337" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (8.37e-6)" "unprognostic (1.53e-1)" "unprognostic (2.89e-2)" "unprognostic (2.15e-3)" "prognostic unfavorable (4.05e-4)" "unprognostic (6.92e-2)" "unprognostic (6.31e-3)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-3)" 20.7 10.4 35.7 11.8 36.1 4.3 7.5 37.8 99.4 7.1 37.8 46.8 32.5 28.6 22.8 15.3 13.1 14.8 67.9 33.5 35.2 11.4 55.6 4.9 9.5 38.6 35.9 7.9 2.0 10.0 5.2 34.0 37.0 14.4 35.3 68.9 3.5 11.2 67.5 13.0 16.6 39.2 37.0 6.6 26.6 29.8 38.3 11.7 8.6 59.6 11.6 11.9 7.1 38.2 111.1 24.0 86.9 74.3 61.9 52.1 272.7 64.6 51.1 52.0 80.9 85.4 67.1 113.8 82.3 61.6 32.6 113.1 126.3 124.8 96.8 75.6 105.2 108.9 63.4 112.9 104.6 123.2 9.9 72.2 144.6 75.7 146.4 79.2 131.4 53.8 131.3 78.0 61.9 19.9 70.2 70.1 271.4 36.7 74.5 67.9 130.7 92.8 67.3 1.9 86.9 46.5 121.8 3.8 97.5 130.0 3.7 48.9 80.9 45.4 72.0 89.3 93.1 39.7 33.9 116.7 137.1 78.5 56.0 0.0 1.4 0.0 1.5 1.6 1.7 0.9 1.8 2.0 2.5 0.3 0.8 1.5 0.1 0.6 0.3 0.2 6.1 0.8 35.7 36.1 37.8 99.4 33.5 35.2 38.6 35.9 37.0 37.0 38.3 38.2 15.1 0.0 2.6 8.5 16.5 89.3 6.5 39.9 87.6 16.9 16.5 9.9 126.3 10.0 5.7 0.0 158.4 77.4 20.3 99.8 0.0 2.5 107.2 14.3 70.7 22.8 3.5 20.2 9.8 3.3 67.6 32.8 67.2 35.8 8.9 322.8 6.4 37.5 15.4 20.2 11.6 17.3 20.3 9.0 15.7 118.3 11.8 12.8 39.2 20.6 4.3 184.8 0.0 9.0 23.8 7.4 7.7 7.5 25.5 16.5 9.3 10.8 3.9 277.5 0.0 38.2 22.1 45.3 23.6 29.6 39.5 46.0 20.9 49.6 23.3 1.3 SLC25A11 "OGC, SLC20A4" ENSG00000108528 "Solute carrier family 25 member 11" Q02978 17 4937130-4940053 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 233.6;skeletal muscle: 314.5;tongue: 450.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021167 Approved NA NA 25000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA021167: AB_1857021" "unprognostic (8.58e-2)" "unprognostic (4.06e-3)" "unprognostic (9.43e-2)" "unprognostic (2.47e-2)" "unprognostic (1.75e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (4.86e-1)" "unprognostic (9.48e-2)" "prognostic favorable (6.41e-6)" "unprognostic (2.84e-1)" "prognostic favorable (2.84e-9)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (1.70e-2)" "unprognostic (1.09e-1)" 35.6 52.5 69.2 33.8 70.7 31.7 32.0 77.7 79.8 35.3 70.8 46.7 47.5 36.7 22.1 50.5 41.6 30.7 233.6 76.8 73.6 66.6 66.7 30.0 40.7 69.2 72.7 30.7 27.9 70.8 36.4 27.6 69.6 34.0 36.1 23.2 41.6 38.4 314.5 48.7 40.2 33.4 70.2 37.5 39.9 10.9 77.0 45.1 38.5 450.4 33.9 38.5 33.3 71.5 51.1 134.6 67.3 66.3 64.7 39.9 47.3 56.2 57.2 96.2 79.3 85.1 24.7 78.3 74.5 55.3 46.8 99.6 88.1 101.5 37.8 99.6 113.8 86.4 70.9 74.5 66.0 37.6 100.7 57.7 65.1 85.4 71.7 46.7 67.8 83.2 38.7 74.1 82.7 91.2 121.6 38.3 35.6 56.1 89.6 108.6 41.4 71.0 74.8 52.6 59.9 62.1 70.9 79.0 65.2 33.6 73.3 58.7 46.0 43.0 28.1 58.8 109.7 39.3 25.4 30.7 84.8 62.6 108.4 126.0 170.3 132.3 98.8 176.8 90.8 87.5 75.1 87.8 160.4 74.3 74.1 81.2 111.8 151.6 165.1 107.0 97.3 186.2 69.2 70.7 77.7 79.8 76.8 73.6 69.2 72.7 69.6 70.2 77.0 71.5 39.7 25.6 23.3 12.7 32.9 38.1 47.1 92.7 25.6 60.3 47.5 51.3 150.6 51.5 40.0 66.2 16.7 132.2 39.0 67.0 185.9 60.7 15.2 30.3 29.7 41.0 27.6 50.3 8.0 53.6 138.7 40.2 30.5 28.2 39.3 45.6 33.5 61.5 109.1 47.1 10.5 51.6 99.7 45.3 44.4 19.6 30.4 56.2 51.6 9.4 106.9 59.2 47.4 9.5 10.4 47.4 58.7 38.4 45.8 43.1 99.9 202.5 26.5 56.0 52.6 43.1 48.4 15.1 31.3 46.9 44.3 102.5 38.4 57.5 88.3 42.1 SLC25A28 "MRS3/4, MRS4L" ENSG00000155287 "Solute carrier family 25 member 28" Q96A46 10 99610522-99620609 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 148.9;Late spermatids: 390.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.87e-3)" "prognostic favorable (2.18e-6)" "unprognostic (8.59e-3)" "unprognostic (6.86e-2)" "unprognostic (4.29e-1)" "unprognostic (1.43e-2)" "unprognostic (3.39e-2)" "unprognostic (9.90e-2)" "unprognostic (1.47e-1)" "unprognostic (1.40e-2)" "unprognostic (9.80e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.12e-1)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (7.62e-3)" 55.6 74.0 107.1 32.8 110.6 86.0 51.1 104.4 125.4 60.1 98.7 82.0 22.9 46.9 46.4 70.5 59.0 24.9 69.2 106.6 108.9 53.6 96.7 73.4 41.6 108.5 112.8 60.9 66.0 32.4 55.7 28.2 109.0 78.6 33.7 54.4 51.7 45.7 100.3 58.8 56.3 35.8 105.8 80.4 58.5 90.2 107.8 30.9 48.6 45.4 37.8 89.8 62.9 111.9 28.7 28.5 17.8 42.8 32.3 40.1 18.1 33.8 40.4 45.2 37.0 22.4 35.2 36.9 19.9 30.8 20.5 47.6 22.1 31.6 27.8 27.5 28.3 16.3 46.4 23.9 31.8 29.3 21.6 33.9 46.0 29.4 58.1 58.9 32.4 32.1 11.7 27.9 23.5 39.6 25.4 66.1 4.2 23.1 21.9 31.9 21.2 20.6 30.0 31.1 11.9 14.9 19.2 20.7 25.4 23.1 37.3 28.8 19.9 27.6 19.0 36.9 41.0 22.8 15.5 18.3 26.5 55.8 11.7 0.0 1.4 4.0 2.7 1.3 1.2 1.7 1.9 1.6 2.1 1.6 1.4 1.2 1.2 1.6 1.3 5.8 2.4 0.7 107.1 110.6 104.4 125.4 106.6 108.9 108.5 112.8 109.0 105.8 107.8 111.9 30.4 12.8 11.0 37.2 11.8 25.4 16.4 17.5 4.6 30.7 12.5 14.1 19.7 15.7 7.3 5.5 20.9 21.0 18.3 9.2 7.9 3.8 148.9 11.1 13.6 17.1 4.2 4.8 34.1 8.0 8.7 15.8 4.1 13.2 6.3 36.2 9.7 19.1 9.8 43.7 34.0 11.9 6.1 9.2 20.0 390.1 12.8 16.2 19.6 20.6 10.6 29.0 8.2 28.6 36.3 6.3 9.6 18.0 10.6 31.1 7.2 8.3 4.0 29.2 13.1 20.5 15.6 63.4 9.2 13.6 27.4 14.5 12.2 58.2 11.4 20.6 SLC25A33 "BMSC-MCP, MGC4399, PNC1" ENSG00000171612 "Solute carrier family 25 member 33" Q9BSK2 1 9539465-9585173 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 27.5" "Cell type enhanced" "Detected in all" "Early spermatids: 422.0;Late spermatids: 559.8;Spermatocytes: 358.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049982 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA049982: AB_2680981" "unprognostic (1.61e-1)" "prognostic favorable (4.86e-4)" "unprognostic (2.94e-2)" "unprognostic (4.80e-2)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.18e-2)" "prognostic favorable (7.02e-4)" "unprognostic (1.88e-3)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" "unprognostic (2.77e-1)" "unprognostic (4.55e-3)" "unprognostic (7.27e-2)" "unprognostic (1.19e-1)" "unprognostic (4.25e-2)" "unprognostic (3.77e-2)" 11.3 3.4 12.4 2.6 13.6 9.0 6.0 15.1 13.8 2.5 11.9 4.6 2.2 3.0 12.6 2.9 3.0 3.7 5.2 12.2 14.5 10.0 12.6 2.7 3.3 14.1 14.7 2.7 3.7 3.9 5.6 1.4 13.7 4.1 3.7 11.2 5.4 2.0 18.1 2.5 2.6 2.7 14.5 2.3 4.4 13.4 15.8 3.5 5.1 27.5 3.5 4.0 2.3 14.5 6.9 3.1 8.7 13.4 7.0 4.0 5.6 6.5 6.1 10.8 9.5 6.9 5.2 19.8 7.8 5.4 11.3 2.8 22.2 4.3 13.3 15.3 13.9 19.5 4.2 27.5 15.1 19.6 14.8 4.8 7.5 10.8 5.2 2.6 6.4 14.5 19.2 10.0 6.1 7.2 12.5 13.4 10.7 12.5 7.3 16.5 9.2 12.8 6.9 3.8 15.1 9.7 7.3 22.2 20.0 7.5 8.2 14.2 2.8 6.8 9.0 9.2 8.4 11.8 23.6 33.5 4.9 21.6 8.4 2.8 0.3 0.1 0.5 0.4 0.3 0.8 0.4 0.3 0.6 0.3 0.6 0.7 0.4 0.5 0.4 0.5 0.0 0.1 12.4 13.6 15.1 13.8 12.2 14.5 14.1 14.7 13.7 14.5 15.8 14.5 25.7 3.2 13.1 59.1 34.4 51.5 107.3 4.2 69.4 15.1 60.0 39.5 9.3 37.1 6.8 9.2 52.1 14.0 32.9 22.5 199.6 11.5 422.0 38.1 19.0 19.9 66.3 8.2 12.3 15.1 38.6 27.2 30.1 39.8 23.6 9.5 11.4 55.8 21.3 10.1 18.2 27.5 6.1 9.2 66.8 559.8 9.9 30.7 32.0 5.6 11.7 195.3 9.2 13.6 13.7 11.5 14.4 10.1 20.4 94.7 6.6 29.5 8.0 53.3 6.6 41.5 37.0 358.5 115.1 42.6 35.8 39.3 22.7 16.7 32.4 96.2 SLC25A42 MGC26694 ENSG00000181035 "Solute carrier family 25 member 42" Q86VD7 19 19063994-19113030 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.7;Hepatocytes: 52.1;Proximal tubular cells: 39.6;Rod photoreceptor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.7;MAIT T-cell: 1.4;memory B-cell: 3.3;memory CD4 T-cell: 1.5;memory CD8 T-cell: 2.4;naive B-cell: 3.2;naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.4;NK-cell: 1.8;T-reg: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.3;NK-cells: 1.8;T-cells: 2.7" "Cell line enhanced" "Detected in many" "K-562: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049449 Approved Supported Mitochondria Yes No "Cluster 43: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA049449: AB_2680772" "unprognostic (2.27e-1)" "prognostic favorable (5.04e-4)" "unprognostic (5.79e-2)" "unprognostic (5.67e-2)" "unprognostic (1.35e-1)" "unprognostic (3.42e-3)" "unprognostic (1.27e-3)" "prognostic favorable (4.11e-4)" "unprognostic (6.89e-2)" "unprognostic (2.73e-1)" "unprognostic (1.37e-3)" "unprognostic (3.04e-2)" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.39e-2)" "unprognostic (4.17e-2)" "unprognostic (2.03e-2)" 8.5 7.5 17.2 4.3 16.9 8.3 7.9 14.5 18.3 13.1 16.7 8.4 5.1 10.1 3.7 5.2 12.5 3.5 15.8 17.9 16.9 34.1 82.0 6.6 9.0 14.9 15.2 16.9 11.3 6.0 14.4 2.6 14.7 9.9 2.4 8.4 9.2 5.2 46.5 6.7 9.3 4.9 13.9 12.7 8.3 7.0 18.0 8.1 25.6 32.6 7.5 9.6 9.1 13.9 7.3 1.0 1.8 3.2 6.8 5.6 2.8 3.5 5.2 5.3 6.0 1.4 14.3 5.2 8.0 3.3 5.3 1.3 3.7 2.9 3.0 1.3 7.0 1.8 2.0 11.8 5.4 0.8 3.6 5.6 2.0 4.0 2.4 4.3 2.4 16.8 20.9 9.2 2.8 6.6 9.0 8.4 1.0 2.0 7.4 6.8 3.2 10.2 2.1 1.3 2.0 1.5 3.7 0.1 1.6 2.4 6.5 4.1 2.2 3.9 2.2 8.2 3.4 10.7 6.2 4.1 4.1 11.2 2.0 0.0 0.1 0.1 2.7 0.3 1.4 3.3 1.5 2.4 0.2 3.2 1.0 1.4 0.0 1.8 0.3 0.4 1.7 0.9 17.2 16.9 14.5 18.3 17.9 16.9 14.9 15.2 14.7 13.9 18.0 13.9 4.6 0.0 13.1 12.4 14.2 3.2 2.8 3.3 2.8 67.7 5.9 6.6 9.7 5.7 4.1 9.2 18.8 7.7 16.5 3.1 13.7 1.5 1.2 2.5 5.4 4.1 8.4 13.7 18.6 3.1 3.8 5.1 4.1 3.6 3.8 8.3 5.3 52.1 1.8 3.3 25.0 3.8 6.1 0.6 1.9 1.6 5.0 1.4 3.6 6.5 1.3 12.5 32.0 16.1 8.6 2.5 4.6 6.4 16.4 2.4 9.2 39.6 3.0 41.4 6.6 9.6 5.8 10.6 7.6 0.9 2.8 4.7 10.9 8.0 3.1 1.7 SLC25A44 "FLJ90431, KIAA0446" ENSG00000160785 "Solute carrier family 25 member 44" Q96H78 1 156193932-156212796 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 114.1;Late spermatids: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 70.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065411 Approved Nucleoplasm,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA065411: AB_2685486" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-1)" "unprognostic (2.44e-3)" "unprognostic (2.75e-1)" "unprognostic (1.32e-1)" "unprognostic (5.72e-2)" "unprognostic (8.92e-2)" "unprognostic (1.97e-1)" "unprognostic (3.58e-1)" "prognostic favorable (2.49e-4)" "unprognostic (3.37e-2)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (2.67e-1)" "unprognostic (8.13e-2)" "unprognostic (2.37e-1)" 18.3 11.6 17.5 10.4 18.7 12.8 9.5 14.4 23.1 8.8 8.5 11.2 18.2 9.5 11.2 11.9 9.2 11.2 14.1 19.5 17.2 27.7 35.3 11.4 10.4 15.8 16.9 6.8 8.8 17.2 13.4 8.3 17.4 9.4 11.5 18.2 8.7 9.3 17.6 11.1 13.0 11.5 13.6 16.6 11.4 12.4 18.0 14.6 10.4 21.2 12.4 14.8 8.4 18.3 18.3 30.5 14.6 19.5 31.0 16.7 11.6 19.2 27.9 33.8 27.5 30.1 16.4 14.4 16.3 28.6 18.3 26.6 53.9 22.5 29.8 16.6 18.0 13.1 18.8 18.4 23.8 17.2 23.2 23.6 19.3 34.3 20.6 16.3 27.8 17.5 14.0 23.0 23.6 32.7 18.1 12.2 34.6 34.6 31.2 11.5 14.8 24.6 44.2 21.2 22.8 30.7 22.3 40.0 26.1 25.6 30.1 27.8 22.7 19.6 16.4 22.0 23.1 23.4 19.2 21.5 21.6 17.8 19.8 14.2 18.2 19.3 9.3 19.1 9.6 8.2 7.4 8.9 13.4 5.4 6.0 7.3 70.5 9.4 16.1 5.8 7.3 13.5 17.5 18.7 14.4 23.1 19.5 17.2 15.8 16.9 17.4 13.6 18.0 18.3 16.4 12.8 22.4 7.5 11.1 27.8 6.2 5.5 10.8 14.4 33.0 25.4 41.1 11.5 11.5 9.2 20.9 5.2 12.0 10.4 5.9 6.0 114.1 17.9 12.3 16.6 6.0 9.5 12.0 5.6 4.0 15.6 12.2 35.4 5.1 5.3 11.7 34.0 7.5 20.2 12.4 11.7 8.2 11.3 34.4 95.6 7.2 19.1 12.4 6.5 10.1 8.2 22.6 5.5 11.6 6.2 6.1 5.7 10.2 6.6 13.8 17.1 5.2 9.0 19.7 40.7 10.8 9.6 10.3 17.6 34.1 8.2 12.8 7.3 8.5 6.9 SLC30A9 "C4orf1, GAC63, HUEL, ZNT9" ENSG00000014824 "Solute carrier family 30 member 9" Q6PML9 4 41990502-42090461 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transcription, Transcription regulation, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004014 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "HPA004014: AB_1080005" "unprognostic (4.26e-2)" "unprognostic (2.20e-1)" "unprognostic (1.31e-3)" "unprognostic (1.44e-2)" "unprognostic (1.14e-1)" "unprognostic (1.01e-1)" "unprognostic (3.19e-2)" "unprognostic (1.82e-1)" "unprognostic (2.63e-2)" "unprognostic (1.43e-1)" "unprognostic (1.55e-1)" "unprognostic (6.99e-2)" "prognostic favorable (2.86e-14)" "unprognostic (4.67e-2)" "unprognostic (1.34e-1)" "unprognostic (2.22e-2)" "unprognostic (1.39e-2)" 8.8 15.4 11.4 6.9 12.4 5.8 13.8 12.0 16.1 11.8 12.2 13.4 12.6 10.3 16.0 9.3 9.9 8.6 21.1 12.8 11.9 30.5 14.2 8.9 7.4 11.1 11.3 11.1 12.9 22.7 14.6 9.4 11.6 13.6 13.9 19.8 12.2 10.0 14.7 9.6 11.6 8.5 10.9 7.9 12.9 6.8 11.5 9.1 17.3 20.5 7.8 9.5 8.0 11.7 12.7 6.2 20.3 23.2 15.3 21.3 11.4 17.3 20.8 14.8 17.5 6.4 16.2 13.0 12.2 20.0 19.1 6.3 17.3 14.3 21.1 4.4 10.2 14.9 10.7 10.9 27.1 20.8 10.3 17.0 14.4 12.7 16.5 23.8 16.3 12.9 20.4 6.0 26.2 6.1 12.0 19.6 15.6 19.7 8.5 5.9 18.4 10.8 30.2 10.6 22.5 25.3 12.3 13.5 15.9 14.3 17.2 15.5 17.7 17.4 10.1 17.6 20.3 11.9 9.5 12.3 23.8 17.4 15.5 3.1 1.8 1.0 1.2 2.3 1.3 1.3 1.3 1.5 2.5 1.1 1.7 1.4 0.8 2.1 1.9 1.8 1.6 1.4 11.4 12.4 12.0 16.1 12.8 11.9 11.1 11.3 11.6 10.9 11.5 11.7 19.7 48.1 44.5 48.3 26.5 15.2 22.8 24.7 24.5 34.9 30.3 16.9 90.7 32.9 33.8 38.6 25.0 44.4 11.4 33.8 103.7 35.9 7.1 27.3 29.2 22.1 33.5 32.2 70.0 36.4 34.0 27.7 37.8 26.8 34.2 33.3 21.4 25.4 24.2 50.5 74.7 36.7 30.5 22.2 21.1 8.7 20.8 23.8 24.9 43.1 28.0 29.7 9.2 63.3 84.7 34.3 17.4 22.6 35.8 27.1 25.5 111.7 43.6 39.3 6.6 29.3 28.1 16.1 18.0 40.8 22.7 49.4 21.2 44.8 38.3 24.2 SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.0;Distal enterocytes: 382.0;Proximal enterocytes: 235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 155.8;AN3-CA: 151.3;SK-BR-3: 156.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" 31.6 66.6 77.2 9.0 99.4 34.5 23.9 77.8 80.0 17.5 39.9 73.5 51.3 32.4 13.0 54.6 17.3 31.3 130.4 76.8 82.1 81.4 4.5 9.2 1.9 89.0 90.5 12.4 20.0 45.6 21.4 36.2 76.9 31.3 30.5 34.7 52.3 35.9 166.6 45.9 75.9 20.7 71.3 13.1 30.8 38.5 87.6 11.9 8.2 75.5 3.0 41.2 36.5 116.6 155.8 6.7 39.5 151.3 14.7 9.9 10.2 22.2 37.7 28.7 35.5 20.1 2.1 0.2 17.0 27.9 33.6 54.3 85.3 78.0 17.0 2.7 83.3 0.6 50.6 59.7 50.0 1.2 10.1 20.9 16.5 27.3 103.3 50.7 14.9 0.9 37.3 2.4 15.7 9.3 0.8 3.6 47.0 30.9 67.0 7.6 5.2 2.1 30.8 29.5 56.0 64.2 33.8 156.8 107.9 9.8 30.9 23.9 14.1 45.2 73.1 58.2 66.5 5.2 3.0 1.8 105.5 4.5 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 77.2 99.4 77.8 80.0 76.8 82.1 89.0 90.5 76.9 71.3 87.6 116.6 5.9 0.0 1.9 14.0 2.7 23.2 14.3 91.1 13.1 142.0 19.6 18.4 106.9 21.5 55.6 5.5 110.5 15.3 2.8 382.0 3.9 4.6 1.5 21.4 38.9 6.5 25.9 23.4 8.2 22.2 37.7 8.8 6.1 16.1 4.5 14.4 3.9 0.9 4.9 119.5 9.9 44.2 38.7 1.9 5.7 3.7 9.0 4.1 24.9 2.8 3.2 19.0 0.0 9.0 23.7 47.5 101.1 8.2 0.8 28.3 235.8 53.3 31.3 49.3 32.9 15.6 19.0 2.9 3.9 16.9 15.6 90.8 2.9 1.5 20.7 18.6 SLIRP "C14orf156, DC50" ENSG00000119705 "SRA stem-loop interacting RNA binding protein" Q9GZT3 14 77708071-77761104 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1099.6;Proximal tubular cells: 1027.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020291 Approved Supported Mitochondria No Yes 32000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020291: AB_1845563" "unprognostic (9.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.62e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.88e-4)" "unprognostic (1.18e-1)" "unprognostic (8.23e-2)" "unprognostic (2.19e-1)" "unprognostic (1.14e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-1)" "unprognostic (2.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.37e-1)" 121.9 131.0 241.0 80.4 251.7 122.7 155.0 250.5 391.0 92.8 228.9 161.3 112.5 91.5 196.3 163.7 89.6 68.3 336.8 249.8 251.6 203.0 211.2 81.1 82.8 251.4 247.5 82.0 110.5 145.2 120.2 91.9 248.6 95.7 141.3 109.9 105.0 90.3 364.5 92.1 107.6 97.0 248.2 92.9 140.2 122.9 245.9 97.4 94.6 442.3 113.5 123.8 101.8 261.2 422.5 867.3 340.9 330.8 226.0 227.7 441.2 240.0 234.8 484.1 419.6 1187.1 387.1 314.2 238.9 284.7 295.6 415.7 645.4 508.0 647.3 166.5 717.2 316.3 816.1 1199.5 343.4 211.8 216.6 242.5 332.3 387.3 428.2 232.4 408.7 403.2 321.2 172.8 430.0 1442.6 325.3 562.2 525.1 938.0 1211.5 294.8 282.9 345.6 508.8 840.3 425.5 274.1 253.3 533.0 360.3 373.7 555.7 360.9 227.0 237.1 422.5 254.0 416.9 184.8 374.7 605.0 325.7 407.2 309.6 88.9 276.1 103.9 105.2 275.3 112.0 169.4 139.0 104.6 239.8 143.1 143.4 120.3 87.8 93.3 288.8 247.4 154.9 216.2 241.0 251.7 250.5 391.0 249.8 251.6 251.4 247.5 248.6 248.2 245.9 261.2 130.4 109.0 140.0 8.5 112.3 178.8 164.5 542.9 92.8 68.8 168.8 154.3 1099.6 270.2 303.9 264.8 47.9 393.0 82.7 330.9 770.9 405.1 548.5 163.7 141.9 169.0 246.8 203.2 10.8 530.1 382.3 166.0 119.3 123.7 171.5 73.1 179.2 793.4 313.6 43.7 9.6 373.1 388.6 202.8 119.5 123.0 168.0 135.2 250.8 2.8 211.4 206.4 93.7 8.5 16.7 440.6 334.4 170.0 136.9 190.5 563.3 1027.1 254.5 126.8 170.9 178.6 202.7 382.6 210.3 178.5 214.4 240.5 80.6 84.7 404.0 163.8 SMG5 "EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5" ENSG00000198952 "SMG5 nonsense mediated mRNA decay factor" Q9UPR3 1 156249224-156282825 "Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072651 Uncertain "Cytoplasmic bodies" No No "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cytoplasmic bodies" "HPA072651: AB_2686544" "unprognostic (2.09e-2)" "unprognostic (3.45e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (3.20e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.70e-9)" "unprognostic (1.28e-1)" "unprognostic (3.21e-3)" "unprognostic (6.90e-2)" "unprognostic (1.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (4.28e-1)" "unprognostic (8.77e-2)" "unprognostic (4.26e-2)" 25.2 43.2 44.5 22.0 46.5 46.7 23.7 43.6 46.0 25.6 42.1 35.4 27.3 27.5 24.6 37.3 27.1 18.8 58.8 42.0 42.8 43.4 47.5 32.7 25.8 49.9 48.3 25.7 28.3 46.3 39.0 26.5 46.9 35.2 22.0 35.3 26.8 23.8 62.8 36.4 32.3 28.0 44.4 33.8 33.4 27.7 50.3 29.4 29.9 43.3 24.8 31.2 25.9 53.3 53.4 45.8 54.8 40.9 52.2 29.5 79.0 54.0 48.2 80.0 67.7 116.2 67.4 48.1 61.6 64.8 63.7 62.8 97.3 68.3 51.4 54.5 80.9 55.6 45.8 64.2 67.6 58.8 54.5 37.4 66.7 76.9 81.5 41.2 52.1 70.4 77.0 47.1 56.9 54.5 48.3 47.5 110.9 97.0 94.6 77.2 41.8 51.1 52.1 63.4 73.4 61.1 68.5 100.6 61.8 71.9 86.8 124.3 44.0 55.4 61.6 59.1 79.6 71.7 17.9 89.1 48.8 57.8 71.7 1.6 3.7 5.2 3.8 3.9 3.1 2.9 2.9 2.8 2.4 2.5 2.5 2.7 4.1 3.0 4.2 2.4 2.0 3.6 44.5 46.5 43.6 46.0 42.0 42.8 49.9 48.3 46.9 44.4 50.3 53.3 9.1 16.0 13.4 21.9 16.8 14.7 7.8 7.3 17.6 12.8 14.7 9.8 39.5 18.6 9.6 20.2 33.3 17.8 10.4 44.8 7.9 12.3 2.8 14.1 9.1 12.9 22.7 9.9 23.9 14.5 10.7 9.4 35.2 16.1 12.7 18.4 9.7 21.6 12.4 18.5 21.4 20.3 8.2 14.4 8.6 5.5 8.4 11.1 5.4 19.7 13.5 11.2 7.2 12.1 24.2 17.9 24.2 7.2 17.9 14.3 23.7 15.5 12.8 12.6 6.6 9.2 10.5 8.5 7.8 16.9 12.1 17.1 14.0 11.4 23.6 15.4 SMIM10L1 ENSG00000256537 "Small integral membrane protein 10 like 1" P0DMW3 12 11171194-11176016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" "unprognostic (2.27e-1)" "unprognostic (5.11e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (3.49e-2)" "unprognostic (1.36e-1)" "unprognostic (2.97e-3)" "unprognostic (3.14e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.71e-4)" "unprognostic (2.80e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.56e-4)" "unprognostic (8.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.70e-4)" 5.9 16.1 12.0 4.8 12.1 5.8 4.9 11.3 15.5 4.4 11.8 9.8 5.2 6.7 7.9 4.2 4.6 3.5 14.4 12.4 12.5 7.5 10.6 4.7 4.7 12.3 12.5 3.8 4.8 5.6 8.8 4.8 12.3 6.6 4.5 7.3 11.5 6.2 21.7 2.7 5.9 5.5 13.0 6.1 6.4 3.2 12.4 6.2 6.0 10.2 4.0 6.9 3.9 12.6 10.5 6.3 16.6 7.3 13.2 9.6 14.5 15.4 9.2 9.9 7.7 13.3 9.2 8.7 6.7 8.7 12.6 6.8 9.9 7.7 12.6 30.3 11.7 15.9 9.2 12.9 9.1 22.4 5.1 8.5 6.7 10.1 10.1 11.8 8.1 14.5 11.6 7.7 11.4 10.1 15.7 18.6 26.9 5.7 8.1 13.0 19.8 9.3 12.5 11.9 8.8 9.7 12.5 7.6 23.0 27.0 4.1 15.1 9.9 17.7 25.1 7.7 15.5 6.6 14.5 21.3 12.9 13.0 16.3 22.1 9.7 11.4 8.9 8.3 9.6 6.1 9.3 9.4 7.9 7.4 10.3 8.5 1.2 12.8 7.9 9.6 10.4 9.0 12.0 12.1 11.3 15.5 12.4 12.5 12.3 12.5 12.3 13.0 12.4 12.6 33.8 16.0 27.4 0.0 25.6 0.0 15.3 0.0 23.3 26.7 33.6 38.2 88.4 35.8 18.0 7.3 25.0 56.7 47.3 9.3 52.8 48.7 5.2 33.1 26.0 36.1 12.2 40.0 0.0 50.7 23.9 28.0 17.3 21.0 16.4 24.9 29.3 34.9 43.8 26.9 0.0 18.5 0.0 25.8 0.0 9.9 26.4 26.8 0.0 0.0 38.5 29.5 56.7 0.0 0.0 52.7 13.3 32.4 41.8 23.4 38.0 68.1 16.8 34.4 32.9 22.9 33.6 11.5 22.0 19.8 0.0 17.9 30.7 46.8 17.3 11.1 SMIM11A "C21orf51, FAM165B, SMIM11" ENSG00000205670 "Small integral membrane protein 11A" P58511 21 34375480-34416961 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 12.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA051321 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Focal adhesion sites" "HPA051321: AB_2681440" "unprognostic (2.62e-2)" "unprognostic (4.28e-2)" "unprognostic (1.27e-1)" "unprognostic (5.86e-3)" "unprognostic (1.90e-1)" "unprognostic (1.66e-1)" "unprognostic (3.04e-1)" "unprognostic (4.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" "unprognostic (8.84e-2)" "unprognostic (4.83e-3)" 10.2 8.9 19.8 12.1 20.6 13.0 6.6 20.4 32.6 10.3 24.4 7.5 14.9 9.7 14.5 9.3 9.2 13.6 21.9 19.9 20.8 17.8 14.5 8.1 15.8 21.4 20.2 16.7 11.6 11.2 3.6 5.8 21.0 10.5 6.5 13.2 14.3 4.8 35.9 6.3 11.7 11.3 21.5 11.4 30.5 6.3 20.0 6.7 20.6 11.4 6.5 12.7 2.7 23.5 24.7 9.8 11.1 33.0 21.0 6.5 22.6 9.0 4.3 12.5 25.1 12.7 22.7 57.4 11.8 11.6 16.5 15.1 18.8 0.7 11.9 32.0 8.9 33.1 23.0 12.7 19.0 55.6 7.8 15.5 10.8 13.6 31.1 24.5 14.2 12.1 51.4 65.7 13.2 13.2 2.2 43.5 52.2 15.5 34.5 31.1 25.2 82.5 10.8 6.2 28.3 20.4 14.8 18.5 39.0 20.3 18.2 25.1 18.1 18.1 13.4 8.0 16.9 25.1 28.3 54.0 33.6 70.0 33.0 5.6 6.3 14.9 6.9 10.1 11.4 6.5 11.7 16.8 8.5 17.1 8.5 11.4 3.6 14.4 9.2 7.6 14.1 9.5 19.8 20.6 20.4 32.6 19.9 20.8 21.4 20.2 21.0 21.5 20.0 23.5 0.1 3.2 2.6 0.0 0.4 0.0 0.4 0.0 0.0 0.8 0.8 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.3 1.9 1.5 0.4 0.1 0.4 0.7 1.2 0.0 0.0 0.7 0.3 0.7 12.8 0.2 0.0 0.2 0.7 1.4 0.7 0.0 0.0 0.8 0.0 0.6 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.3 0.4 0.6 0.3 1.4 2.2 2.2 0.4 0.0 0.3 0.3 0.6 0.5 0.0 0.0 0.1 0.4 0.1 0.6 0.1 SMIM12 "C1orf212, FLJ90372" ENSG00000163866 "Small integral membrane protein 12" Q96EX1 1 34712737-34859755 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065331 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA065331: AB_2685470" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.64e-1)" "unprognostic (2.05e-1)" "unprognostic (5.71e-2)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "prognostic favorable (1.15e-5)" "unprognostic (7.33e-2)" "unprognostic (6.70e-2)" "unprognostic (3.58e-2)" "unprognostic (2.52e-2)" 40.2 56.6 31.7 26.5 32.1 24.8 33.5 29.5 35.3 20.9 29.2 34.0 30.1 26.0 17.7 41.3 23.5 17.3 53.8 31.5 35.7 42.3 87.9 31.6 25.0 32.6 32.7 17.1 26.4 31.8 26.9 24.8 33.1 19.9 28.0 12.8 24.1 20.5 56.2 29.7 30.8 31.5 29.6 31.9 30.4 28.0 31.9 30.3 24.9 51.1 27.3 29.2 25.7 33.3 52.9 39.8 43.3 31.6 55.2 43.3 30.1 55.8 48.1 70.2 60.3 40.0 65.0 55.1 49.2 57.6 55.5 51.7 55.5 74.7 53.5 67.3 41.6 98.1 65.6 49.1 51.3 107.9 55.4 66.2 71.9 76.5 61.3 25.3 72.9 47.0 71.0 72.3 63.0 38.6 52.6 55.4 70.1 40.8 52.7 44.1 42.7 71.7 62.2 54.6 41.5 32.9 52.0 48.1 81.5 53.9 32.8 29.9 69.9 47.8 49.3 74.3 66.7 40.4 60.2 56.9 45.2 63.7 32.1 104.2 76.0 126.4 65.8 82.0 77.9 57.7 60.4 72.0 86.0 59.2 50.1 64.3 50.2 62.6 67.5 62.4 76.2 87.5 31.7 32.1 29.5 35.3 31.5 35.7 32.6 32.7 33.1 29.6 31.9 33.3 51.2 25.6 13.1 4.9 37.0 68.2 26.3 49.8 23.3 14.4 36.4 30.1 33.9 42.9 30.4 22.0 10.4 50.7 38.5 46.7 86.1 78.7 58.3 17.1 19.0 56.2 21.8 53.9 10.4 83.7 60.2 24.9 20.9 20.6 23.5 18.9 48.2 89.3 83.8 20.2 9.5 23.4 46.8 41.7 61.6 32.7 14.9 41.0 39.2 7.5 89.8 24.9 54.6 6.6 7.0 87.5 41.0 23.3 27.5 40.8 62.9 90.6 26.8 17.3 13.1 21.8 52.3 37.6 23.0 41.4 75.6 58.0 40.8 33.7 39.6 41.7 SMIM20 "C4orf52, MITRAC7, PNX" ENSG00000250317 "Small integral membrane protein 20" Q8N5G0 4 25861830-25929874 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016552 Approved Approved Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" Nucleoli "HPA016552: AB_1859536" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" "unprognostic (1.78e-1)" "unprognostic (6.52e-3)" "unprognostic (1.55e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.46e-1)" "unprognostic (1.02e-1)" "unprognostic (5.42e-2)" "unprognostic (2.86e-1)" "prognostic favorable (8.97e-5)" "unprognostic (5.51e-2)" "unprognostic (5.84e-2)" "unprognostic (1.53e-1)" "unprognostic (5.12e-3)" 27.9 36.7 36.7 16.6 37.7 13.1 27.2 38.1 50.2 22.2 39.8 30.9 39.9 23.9 72.2 15.7 23.8 23.9 46.8 36.5 38.4 46.0 38.2 19.7 30.4 36.9 36.1 33.9 43.4 28.2 17.6 14.1 36.9 23.9 25.5 29.9 35.1 17.5 95.9 13.9 35.1 17.8 37.9 23.6 38.6 20.5 36.8 17.4 31.4 61.4 24.8 28.8 19.1 39.2 29.9 24.5 32.3 31.3 34.9 75.4 43.0 28.4 34.3 24.0 30.4 21.9 51.6 48.8 48.1 31.7 49.6 8.5 37.9 36.3 33.4 27.9 30.1 28.3 16.4 42.0 59.1 34.0 18.0 53.9 71.6 30.6 46.1 46.7 18.7 32.5 45.9 15.5 29.6 19.1 37.0 57.5 61.0 39.6 36.1 30.1 42.0 31.7 53.5 21.6 41.3 38.4 18.3 12.7 66.0 35.2 26.3 47.5 31.4 25.8 30.5 29.3 36.8 30.2 26.9 52.6 39.2 35.6 33.4 30.6 31.5 15.9 26.2 37.7 34.5 47.3 37.5 33.2 36.9 47.9 50.4 41.1 16.3 35.6 29.4 38.3 42.9 31.7 36.7 37.7 38.1 50.2 36.5 38.4 36.9 36.1 36.9 37.9 36.8 39.2 21.5 9.6 41.6 9.4 48.0 21.9 30.4 89.4 26.7 7.7 49.8 63.1 61.8 61.5 59.0 36.8 8.4 63.7 22.5 50.9 131.0 70.0 11.5 34.7 30.6 23.1 19.3 9.2 3.8 62.5 59.7 40.0 31.6 34.6 10.8 37.1 21.8 66.5 69.7 1.7 4.6 64.0 59.0 62.9 32.1 23.1 37.6 44.5 44.4 4.7 42.9 95.3 38.1 9.5 7.9 46.2 44.6 48.2 38.4 38.9 130.1 166.5 47.0 22.2 72.3 26.8 35.8 44.5 36.4 27.3 19.5 43.8 29.8 71.2 65.4 30.8 SMIM26 "LINC00493, LOC388789" ENSG00000232388 "Small integral membrane protein 26" A0A096LP01 20 18567347-18569563 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 252.6;Breast myoepithelial cells: 317.5;Distal tubular cells: 389.4;Proximal tubular cells: 588.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068733 Approved Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA068733: AB_2686024" "unprognostic (1.20e-2)" "unprognostic (5.85e-2)" "unprognostic (2.83e-1)" "unprognostic (8.06e-2)" "unprognostic (2.68e-1)" "unprognostic (1.65e-1)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.67e-3)" "unprognostic (2.16e-1)" "unprognostic (2.68e-2)" "unprognostic (2.40e-2)" "unprognostic (2.02e-1)" "unprognostic (3.18e-1)" "prognostic favorable (7.84e-5)" 76.0 104.3 92.2 43.6 96.2 83.4 107.0 102.7 123.1 72.8 103.9 89.8 63.2 67.2 134.8 71.0 78.9 67.9 136.4 93.6 97.0 96.1 117.7 53.7 72.6 94.8 93.6 113.0 103.4 99.4 90.7 51.3 96.9 71.3 69.8 63.1 91.1 61.9 243.1 69.2 65.8 56.5 96.2 57.8 98.5 37.6 94.4 88.7 85.2 213.5 73.6 79.7 63.6 103.4 99.3 129.1 94.3 98.0 85.9 116.0 110.8 72.3 86.5 83.4 95.2 80.9 113.0 99.4 81.1 79.7 149.1 106.8 90.4 120.2 95.9 42.5 112.9 131.7 59.4 270.2 162.4 86.6 96.5 100.0 159.4 94.6 152.2 144.7 128.1 120.8 98.5 89.3 105.4 125.0 104.0 240.4 53.8 188.5 153.6 67.4 110.0 136.8 192.0 100.4 92.8 98.1 77.2 145.6 297.5 82.9 106.8 126.0 65.8 58.1 60.8 71.7 76.6 85.0 229.8 113.7 52.2 56.2 44.4 142.4 133.5 108.6 96.5 116.6 102.8 155.6 131.7 112.3 164.5 145.7 145.0 139.2 241.3 99.5 112.8 157.7 150.0 130.5 92.2 96.2 102.7 123.1 93.6 97.0 94.8 93.6 96.9 96.2 94.4 103.4 83.8 128.2 83.8 0.0 44.4 0.0 0.0 0.0 0.0 0.0 252.6 317.5 0.0 0.0 35.9 171.0 0.0 205.5 62.6 0.0 389.4 146.2 0.0 185.2 95.5 36.4 0.0 0.0 0.0 214.3 137.9 57.8 0.0 118.7 35.3 100.5 0.0 0.0 188.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.3 0.0 0.0 66.2 0.0 0.0 0.0 0.0 187.7 0.0 0.0 12.1 0.0 0.0 588.2 87.5 0.0 0.0 0.0 45.9 0.0 0.0 0.0 0.0 208.0 37.2 108.8 0.0 0.0 SMIM4 C3orf78 ENSG00000168273 "Small integral membrane protein 4" Q8WVI0 3 52534013-52579237 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 121.9;skeletal muscle: 130.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 252.4;Distal tubular cells: 213.2;Proximal tubular cells: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047771 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA047771: AB_2680150" "unprognostic (3.76e-3)" "unprognostic (3.19e-2)" "unprognostic (4.54e-2)" "unprognostic (4.89e-1)" "unprognostic (2.40e-1)" "unprognostic (1.48e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.78e-5)" "unprognostic (3.25e-2)" "unprognostic (4.25e-2)" "prognostic favorable (5.00e-4)" "unprognostic (6.35e-2)" "prognostic favorable (1.63e-4)" "unprognostic (8.72e-3)" "unprognostic (2.28e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-2)" 22.6 121.9 14.6 12.9 15.3 7.4 22.1 21.8 20.5 16.0 20.5 19.1 12.3 14.3 10.4 16.3 14.5 3.7 100.3 15.3 15.5 37.3 20.2 20.3 10.5 15.6 18.2 41.5 25.7 31.6 56.4 6.1 16.9 26.2 10.4 13.9 28.9 13.6 130.3 20.1 15.0 5.0 15.0 15.8 20.4 17.3 15.4 6.6 48.6 50.2 8.7 20.2 13.3 18.0 58.7 19.0 22.9 58.5 26.5 13.7 47.0 25.9 12.0 29.2 25.3 24.6 15.4 25.1 11.6 10.9 29.4 30.2 7.6 20.9 11.8 16.9 60.1 23.6 58.2 50.2 40.1 28.4 31.6 29.6 12.7 24.6 17.7 15.8 26.8 27.0 31.9 36.4 19.9 25.4 26.4 39.4 39.1 31.9 42.4 18.1 22.2 50.1 17.0 25.2 24.9 31.4 50.6 16.5 52.6 12.9 17.0 23.6 24.0 16.0 53.1 76.4 53.5 42.3 50.6 57.3 87.9 52.2 22.5 8.1 44.1 17.3 19.1 35.8 18.8 24.6 27.3 23.9 49.7 22.7 29.1 27.0 1.6 22.5 15.2 26.5 29.6 20.0 14.6 15.3 21.8 20.5 15.3 15.5 15.6 18.2 16.9 15.0 15.4 18.0 35.4 48.1 46.3 1.3 30.3 27.1 37.3 52.2 41.5 17.6 80.9 84.1 252.4 60.1 63.1 53.3 12.5 42.9 26.6 58.3 213.2 52.9 21.9 71.9 30.6 32.8 79.3 22.1 1.9 86.1 24.7 36.0 34.1 48.9 59.5 16.9 55.6 160.4 116.4 3.3 2.1 62.9 30.5 80.8 46.7 15.1 65.0 51.1 37.4 0.0 28.5 102.8 15.5 2.5 3.2 57.8 39.9 101.2 19.7 19.7 89.5 215.6 52.1 15.3 46.0 22.8 56.8 9.8 14.2 34.8 34.5 27.6 25.8 44.3 73.5 23.6 SMIM8 "C6orf162, dJ102H19.2, DKFZP586E1923" ENSG00000111850 "Small integral membrane protein 8" Q96KF7 6 87322583-87399749 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007401, HPA067453" Approved Approved Vesicles NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA007401: AB_1078357, HPA067453: AB_2685844" "unprognostic (2.54e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.90e-1)" "unprognostic (1.56e-2)" "unprognostic (3.16e-2)" "unprognostic (3.09e-2)" "unprognostic (6.17e-2)" "unprognostic (5.31e-2)" "unprognostic (6.12e-3)" "unprognostic (1.86e-5)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (2.01e-1)" "unprognostic (3.06e-2)" "unprognostic (2.86e-2)" "unprognostic (4.01e-1)" 5.0 5.0 8.0 3.8 8.0 6.0 5.2 8.5 9.5 6.4 8.1 6.0 5.2 6.5 6.7 4.1 5.5 2.7 7.7 8.1 8.3 7.3 7.0 3.9 5.0 7.8 8.0 6.5 4.7 6.2 7.2 3.4 7.8 4.7 4.6 8.7 4.0 3.9 10.6 4.3 4.8 4.1 8.1 4.1 4.1 4.9 8.5 6.7 4.8 8.7 4.0 5.3 5.5 8.0 5.3 4.6 9.3 16.2 5.3 6.0 4.1 5.8 4.5 4.8 9.2 3.2 4.8 10.8 6.8 5.8 8.4 6.5 7.6 4.4 9.1 9.6 8.2 15.9 5.2 6.4 5.0 16.8 5.5 5.7 5.9 4.9 5.2 5.4 7.0 13.8 18.1 17.7 5.5 4.0 10.1 13.3 5.7 7.9 7.1 16.1 13.8 6.2 6.2 5.2 15.9 6.5 8.5 5.0 10.1 8.4 4.6 16.5 6.8 2.5 7.2 10.8 5.7 7.8 13.6 7.2 8.1 7.9 7.6 5.8 8.8 15.7 11.2 8.6 11.4 18.5 13.2 13.6 10.1 11.4 19.3 16.9 14.7 9.7 10.3 8.5 18.4 9.1 8.0 8.0 8.5 9.5 8.1 8.3 7.8 8.0 7.8 8.1 8.5 8.0 19.4 12.8 5.8 18.9 17.6 13.8 20.6 29.7 8.6 24.4 12.8 16.0 47.3 17.2 16.6 23.9 37.5 17.7 8.7 8.0 45.0 10.7 18.7 32.1 19.0 15.0 8.5 17.1 21.7 10.3 12.3 17.8 12.8 9.6 5.1 31.4 22.5 13.8 14.9 37.0 19.8 9.4 36.7 12.3 11.5 14.5 15.8 11.1 8.8 8.4 11.0 28.4 13.4 8.0 13.3 8.1 11.6 20.7 14.0 10.1 15.5 23.0 17.5 22.9 26.3 21.1 17.9 23.9 28.4 10.7 14.8 14.9 14.8 30.7 16.5 13.4 SNAPC5 SNAP19 ENSG00000174446 "Small nuclear RNA activating complex polypeptide 5" O75971 15 66490135-66497780 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 118.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024379 Uncertain Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA024379: AB_2671552" "unprognostic (4.43e-2)" "unprognostic (1.53e-3)" "unprognostic (4.39e-3)" "unprognostic (4.56e-2)" "unprognostic (3.49e-2)" "unprognostic (2.31e-1)" "unprognostic (1.06e-1)" "unprognostic (8.07e-2)" "unprognostic (1.12e-2)" "unprognostic (3.39e-2)" "unprognostic (3.13e-1)" "unprognostic (6.28e-2)" "unprognostic (1.64e-2)" "unprognostic (1.25e-1)" "unprognostic (2.21e-1)" "unprognostic (9.40e-2)" "unprognostic (5.69e-2)" 22.4 26.0 31.5 17.3 32.0 15.0 21.8 33.3 40.5 20.4 34.9 32.9 15.7 25.1 41.1 15.8 22.9 13.9 42.3 32.4 34.2 33.0 35.1 19.4 23.8 31.8 33.2 20.9 22.3 32.9 27.4 18.2 33.0 24.4 18.7 28.6 18.5 22.1 60.1 15.1 19.7 20.2 31.3 22.8 23.2 32.6 33.3 21.3 26.9 27.5 22.3 27.3 17.8 33.6 17.3 54.2 23.4 50.4 27.8 26.5 26.3 19.4 27.1 24.5 17.2 31.1 40.3 21.2 44.6 22.6 22.4 35.5 62.6 27.0 27.3 37.7 34.6 28.5 56.2 47.0 33.0 72.8 30.2 22.4 33.2 20.2 49.9 16.5 17.0 38.6 92.8 43.3 18.2 37.7 35.0 28.5 24.3 72.2 23.0 33.8 23.0 79.5 30.2 24.9 30.1 24.3 22.1 44.0 86.5 49.4 40.5 48.7 17.8 23.0 43.2 25.1 33.3 30.2 56.5 36.3 23.7 93.2 47.9 32.5 26.7 34.7 33.6 43.3 42.3 43.8 40.4 45.2 22.6 32.7 53.5 45.3 13.0 49.2 47.0 39.1 50.7 32.3 31.5 32.0 33.3 40.5 32.4 34.2 31.8 33.2 33.0 31.3 33.3 33.6 24.2 22.4 19.2 13.1 20.1 9.4 16.2 33.0 8.6 13.7 19.1 24.5 53.1 18.6 27.9 27.6 10.4 33.4 23.9 13.9 84.1 27.1 118.4 28.4 18.1 23.3 13.9 17.9 8.6 47.6 26.6 22.5 11.7 14.0 19.6 25.1 12.5 48.2 47.2 18.5 10.2 18.1 38.7 18.2 11.8 98.3 26.8 20.3 26.6 8.4 33.2 22.2 43.3 8.5 13.6 27.9 11.1 27.8 19.2 28.7 17.1 79.7 46.4 19.7 0.0 21.3 25.5 92.3 40.7 15.7 9.7 22.3 26.0 30.0 18.6 19.2 SNAPIN "BLOC1S7, BORCS3, SNAPAP" ENSG00000143553 "SNAP associated protein" O95295 1 153658703-153661852 "Predicted intracellular proteins, Transporters" "Exocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046974 Approved Approved "Nucleoli,Golgi apparatus" NA NA 20000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" Nucleoli "HPA046974: AB_10962506" "unprognostic (3.65e-1)" "unprognostic (1.67e-1)" "unprognostic (1.47e-1)" "unprognostic (5.66e-2)" "unprognostic (1.75e-1)" "unprognostic (2.06e-1)" "unprognostic (1.64e-3)" "unprognostic (1.54e-1)" "unprognostic (4.86e-2)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (5.42e-4)" "unprognostic (2.31e-1)" "unprognostic (4.73e-1)" "unprognostic (1.31e-3)" "unprognostic (4.89e-2)" 34.6 50.8 41.5 18.5 42.9 13.1 30.3 44.3 43.0 23.9 38.7 35.7 12.8 30.7 34.1 35.1 27.5 21.7 63.7 39.9 43.5 37.8 32.1 21.0 27.4 43.1 42.3 24.0 17.5 41.2 16.4 19.0 42.9 24.4 20.2 25.1 22.1 29.4 91.5 27.9 23.2 30.4 44.5 30.9 26.3 19.2 43.0 30.6 25.5 77.0 31.9 31.1 23.5 45.1 50.8 60.6 51.5 31.0 63.2 42.7 32.4 41.7 46.1 57.8 43.9 43.9 39.3 35.8 82.6 42.9 29.0 65.6 42.5 54.4 40.9 49.3 57.4 39.6 41.3 21.1 65.4 39.3 24.4 50.5 41.1 43.6 49.0 61.0 54.8 41.7 34.7 27.8 59.5 82.7 46.0 23.9 27.5 78.6 64.7 42.9 44.1 96.8 65.0 47.6 38.9 67.8 48.0 55.0 57.8 50.3 84.0 43.5 48.4 27.2 40.5 54.4 40.0 65.6 77.4 56.0 51.4 24.9 36.1 106.2 146.9 139.7 86.8 154.1 100.6 130.1 88.2 88.9 153.5 119.6 96.9 87.9 30.4 118.1 126.8 115.6 136.3 146.6 41.5 42.9 44.3 43.0 39.9 43.5 43.1 42.3 42.9 44.5 43.0 45.1 41.7 19.2 16.6 7.2 31.6 20.6 35.1 88.7 35.9 14.2 39.1 44.4 39.8 40.0 45.3 29.5 8.4 64.4 35.9 18.0 74.3 71.4 9.6 31.5 24.2 34.9 13.8 33.6 5.9 65.2 49.5 31.2 16.3 25.6 30.4 31.9 40.7 35.1 90.2 21.9 6.5 20.0 40.7 48.3 21.8 26.6 30.7 34.7 26.6 4.7 76.5 84.8 59.8 8.0 14.4 53.5 25.5 49.7 23.8 34.7 26.6 76.7 40.9 21.7 46.0 25.3 39.7 29.3 42.6 45.5 23.4 73.7 26.9 44.2 24.6 36.2 SNRNP27 "RY1, U4/U6.U5-27K" ENSG00000124380 "Small nuclear ribonucleoprotein U4/U6.U5 subunit 27" Q8WVK2 2 69893956-69905575 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034541 Approved Approved Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA034541: AB_10602408" "unprognostic (2.24e-1)" "unprognostic (6.11e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.89e-2)" "unprognostic (1.28e-2)" "unprognostic (1.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.61e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-1)" "unprognostic (3.18e-1)" "unprognostic (4.35e-3)" "unprognostic (9.12e-2)" "unprognostic (2.16e-1)" "unprognostic (2.26e-1)" "unprognostic (1.86e-1)" 31.0 33.4 25.3 23.9 26.6 43.2 26.1 28.0 40.1 19.9 21.5 18.2 17.4 23.5 24.3 19.8 19.1 21.5 39.5 27.3 27.6 23.5 24.6 19.2 32.8 23.6 26.5 21.7 18.5 32.1 16.3 30.3 25.2 23.7 20.9 25.3 21.8 19.3 62.2 19.5 20.4 24.0 26.0 22.6 18.4 14.2 25.3 31.7 26.9 71.8 27.7 24.8 13.4 30.7 27.9 16.2 52.0 31.4 44.7 49.0 41.7 38.5 45.4 54.2 42.9 34.0 31.3 29.6 30.5 31.5 56.0 15.3 34.9 16.1 67.3 33.3 34.1 34.2 14.4 42.2 40.1 43.6 57.9 36.0 38.6 35.4 30.4 44.4 42.0 41.6 49.0 46.6 72.1 15.6 59.4 73.9 38.1 30.1 16.2 46.0 42.9 31.1 60.0 18.5 53.0 41.9 28.7 30.8 42.7 39.0 28.1 35.4 24.6 37.1 51.3 53.7 58.5 28.5 29.9 45.7 33.2 52.4 71.7 43.2 25.1 38.9 23.6 23.5 25.2 37.9 25.7 23.4 22.2 32.2 27.8 27.7 13.7 32.2 25.2 40.8 30.3 25.1 25.3 26.6 28.0 40.1 27.3 27.6 23.6 26.5 25.2 26.0 25.3 30.7 45.3 54.5 39.3 6.5 57.1 49.1 40.5 47.0 44.9 31.6 53.0 32.4 60.7 47.1 36.1 62.5 14.6 49.2 69.9 40.5 74.3 57.7 37.4 37.0 44.8 42.0 38.9 82.7 14.1 55.1 70.1 50.5 18.8 44.6 60.0 24.5 56.4 78.8 57.4 23.5 11.6 52.7 22.4 57.7 46.6 12.4 51.3 48.5 37.4 8.4 50.6 41.8 68.0 4.0 7.6 70.4 42.8 57.9 60.2 34.3 33.9 63.8 47.2 31.2 39.5 32.4 45.2 76.2 61.7 33.9 46.0 52.5 51.7 20.3 37.5 37.7 SNRPN "HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN" ENSG00000128739 "Small nuclear ribonucleoprotein polypeptide N" P63162 15 24823637-24978723 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 457.8;Horizontal cells: 333.1;Proximal tubular cells: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 789.5;SuSa: 505.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003482, HPA067842" Approved Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA003482: AB_1857337, HPA067842: AB_2685909" "unprognostic (9.91e-2)" "unprognostic (1.03e-3)" "unprognostic (2.79e-1)" "unprognostic (1.66e-2)" "unprognostic (3.71e-2)" "unprognostic (2.32e-2)" "unprognostic (1.08e-1)" "unprognostic (2.72e-2)" "unprognostic (9.44e-3)" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (6.59e-2)" "prognostic favorable (8.93e-8)" "unprognostic (4.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" "unprognostic (6.74e-2)" 54.8 181.8 453.6 46.5 472.5 36.5 69.4 441.8 553.5 112.3 351.6 87.3 36.4 65.2 332.5 44.0 121.9 141.2 483.2 474.3 510.7 192.0 69.9 76.4 93.5 454.7 440.5 147.8 111.8 243.4 375.5 37.4 458.5 174.2 34.8 161.7 125.7 147.6 232.7 38.2 62.5 59.0 415.8 85.2 88.3 60.7 467.8 136.8 300.4 272.4 80.6 82.5 66.4 470.8 1.0 148.6 260.8 180.1 153.4 69.5 1.1 46.9 100.0 31.7 57.8 138.1 69.1 0.2 91.6 118.7 47.9 26.7 0.0 142.7 18.2 81.1 0.1 89.3 90.1 151.5 181.8 107.1 76.8 132.6 60.6 69.4 81.8 213.2 95.7 189.8 24.8 0.4 183.3 0.0 216.9 1.5 789.5 0.0 63.0 113.3 97.8 0.5 172.3 222.2 155.7 147.1 0.7 3.6 174.0 505.7 93.6 271.3 62.3 79.2 78.2 0.3 28.8 215.3 126.9 140.4 65.9 72.9 59.8 234.8 68.0 106.8 313.9 74.2 355.8 371.9 385.3 359.0 65.2 342.1 508.0 420.8 18.5 291.2 77.4 531.9 434.4 581.7 453.6 472.5 441.8 553.5 474.3 510.7 454.7 440.5 458.5 415.8 467.8 470.8 57.1 9.6 45.5 0.0 106.2 2.2 102.6 4.4 53.5 171.0 77.1 96.5 185.2 218.8 23.0 178.4 52.1 1.0 157.6 10.0 457.8 150.0 92.9 36.8 27.9 57.7 142.7 31.1 0.0 81.6 1.2 54.9 27.5 24.5 62.7 136.9 63.1 31.9 62.7 333.1 0.0 34.5 6.1 28.9 2.5 111.3 77.3 38.1 0.0 0.0 43.8 210.3 115.4 0.0 0.0 61.5 33.7 116.6 86.7 110.6 38.7 300.2 26.9 112.3 52.6 61.5 65.0 67.9 54.0 22.1 1.7 1.6 104.2 110.4 23.6 65.1 SRP14 "ALURBP, MGC14326" ENSG00000140319 "Signal recognition particle 14" P37108 15 40035690-40039181 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053738, HPA065118" Approved Nucleoplasm,Nucleoli NA NA 440000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA053738: , HPA065118: " "unprognostic (2.52e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-3)" "unprognostic (1.01e-2)" "unprognostic (1.04e-1)" "unprognostic (5.39e-3)" "unprognostic (2.97e-1)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (7.99e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.31e-4)" "unprognostic (2.20e-1)" "unprognostic (8.03e-3)" "unprognostic (1.41e-3)" "unprognostic (4.94e-2)" 309.1 307.5 330.1 118.1 327.1 252.7 300.4 323.8 426.0 301.7 320.4 272.5 121.5 311.2 282.1 257.7 270.7 155.8 390.1 317.9 349.3 391.5 229.5 220.8 168.0 357.0 402.7 323.5 192.4 324.3 306.8 143.8 339.7 264.4 158.9 212.8 237.8 158.9 354.7 201.2 215.7 163.4 321.1 219.7 247.6 165.6 326.2 276.9 275.6 338.5 172.9 266.7 253.9 355.1 131.8 163.7 399.5 301.4 300.0 275.5 189.4 232.4 265.0 213.4 223.3 297.8 113.7 107.9 245.0 305.1 319.5 216.6 322.8 260.9 207.0 257.5 230.3 258.3 530.2 364.0 231.4 238.2 211.8 276.0 298.3 177.8 213.3 391.0 360.6 297.7 280.2 204.2 356.3 204.5 370.2 291.4 217.6 520.1 301.3 247.6 176.8 192.6 477.5 401.7 287.2 255.0 231.2 243.2 171.2 243.7 332.8 448.6 290.9 240.4 160.3 229.4 171.1 161.8 494.7 291.0 234.7 255.4 229.7 729.8 525.0 875.7 484.5 485.8 473.9 600.9 547.9 549.0 562.5 509.0 522.0 510.2 452.7 525.9 459.5 1148.0 755.1 1262.6 330.1 327.1 323.8 426.0 317.9 349.3 357.0 402.7 339.7 321.1 326.2 355.1 1378.8 461.6 415.0 83.2 577.0 667.1 861.7 1395.7 427.4 432.9 617.7 914.5 880.3 649.1 906.9 995.0 125.1 867.3 812.5 742.7 2551.3 1366.9 353.1 1215.7 729.8 957.7 554.0 619.4 39.4 1087.2 1100.4 699.1 324.7 1513.6 564.0 669.5 654.7 819.4 1022.1 348.3 56.1 676.9 1226.8 631.1 882.8 377.3 1039.8 645.8 789.8 36.5 1174.3 1262.8 619.0 39.2 76.0 1240.7 894.4 986.9 610.9 826.3 874.5 2276.2 935.5 477.3 624.5 651.9 749.3 779.9 643.1 631.5 710.3 758.8 644.1 831.9 673.2 975.0 SRXN1 "C20orf139, dJ850E9.2, Npn3, SRX1, YKL086W" ENSG00000271303 "Sulfiredoxin 1" Q9BYN0 20 646615-653200 "Enzymes, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Ductal cells: 4.4;Erythroid cells: 4.8;Excitatory neurons: 4.5;Exocrine glandular cells: 6.8;Inhibitory neurons: 5.8;Pancreatic endocrine cells: 6.5;Squamous epithelial cells: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 12.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 12.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" "unprognostic (7.31e-3)" "unprognostic (6.08e-3)" "unprognostic (2.50e-1)" "unprognostic (5.49e-2)" "unprognostic (1.70e-2)" "unprognostic (1.18e-3)" "prognostic unfavorable (6.22e-5)" "unprognostic (1.37e-3)" "unprognostic (1.69e-1)" "unprognostic (1.58e-2)" "unprognostic (5.26e-2)" "unprognostic (2.48e-1)" "unprognostic (7.71e-2)" "unprognostic (1.79e-2)" "unprognostic (7.57e-2)" "unprognostic (1.57e-2)" "unprognostic (1.52e-3)" 20.8 62.7 24.7 10.3 25.1 24.0 12.4 26.7 29.1 18.4 21.8 16.6 18.0 16.5 15.0 63.0 15.3 16.2 37.3 24.1 32.2 23.3 36.7 21.2 5.7 29.2 30.3 16.6 16.0 32.7 22.2 14.0 29.2 15.7 15.1 20.0 18.2 18.3 45.6 11.5 16.7 19.2 25.1 14.5 32.1 8.5 30.5 4.6 26.9 21.7 10.5 26.1 22.7 22.8 119.4 201.0 13.2 26.3 54.5 60.3 30.0 83.6 64.9 58.4 34.2 69.4 63.5 21.8 52.3 133.8 260.2 58.5 50.3 132.9 56.0 23.2 28.2 86.6 43.8 221.7 73.4 37.4 51.4 38.7 121.5 79.3 76.5 47.9 64.3 32.5 76.5 88.5 64.8 35.4 0.2 20.5 26.6 183.8 73.8 0.4 18.1 45.7 41.0 42.3 16.8 32.2 65.5 144.5 98.8 35.8 49.3 23.0 66.0 80.9 56.5 73.5 119.6 23.1 63.7 17.3 51.5 18.0 67.8 2.4 2.0 3.0 2.0 1.8 1.4 0.4 1.0 2.5 1.0 0.0 0.0 0.7 12.3 0.5 2.2 0.1 1.1 0.4 24.7 25.1 26.7 29.1 24.1 32.2 29.2 30.3 29.2 25.1 30.5 22.8 0.2 0.0 0.0 3.3 0.3 0.1 0.1 0.2 1.8 0.7 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.2 2.9 0.0 4.4 0.0 0.2 0.5 0.6 1.2 4.8 4.5 6.8 0.3 0.8 1.5 0.3 0.0 0.1 0.0 0.4 1.0 0.0 5.8 1.4 0.0 0.0 0.3 0.1 0.0 1.3 0.0 3.7 2.1 0.2 0.0 1.0 0.9 6.5 0.8 0.4 2.4 0.3 2.8 0.2 0.1 0.3 0.0 0.1 1.6 0.0 0.0 9.7 0.0 0.0 0.9 0.1 2.0 0.0 STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB033965: AB_2302780, HPA064958: AB_2685391, HPA064978: AB_2685397" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.56e-5)" "prognostic favorable (3.89e-6)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.72e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.38e-6)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (2.64e-2)" "unprognostic (2.42e-2)" 44.7 54.3 57.8 46.7 62.4 34.3 43.9 61.9 53.2 33.9 60.6 57.6 55.7 29.8 30.5 36.8 44.0 29.1 98.5 49.8 61.4 80.3 62.8 61.1 70.6 56.4 55.5 29.4 42.2 69.7 23.6 29.3 54.9 39.0 56.2 54.4 65.2 45.7 202.5 35.2 45.4 37.6 60.5 53.1 44.6 21.1 66.9 56.2 56.6 174.0 86.9 42.1 27.0 74.4 128.8 79.1 102.3 106.2 134.9 66.9 150.1 122.6 107.0 121.2 129.6 188.8 117.7 228.7 129.0 98.6 95.8 102.3 183.3 106.4 157.3 147.2 131.9 204.1 74.3 218.3 62.2 158.1 106.9 65.4 77.9 101.0 99.1 77.2 123.2 92.6 211.1 89.2 108.8 113.0 175.9 161.0 173.3 110.3 115.2 171.6 156.4 227.1 73.2 162.2 191.6 90.5 62.5 201.8 115.8 126.0 60.5 171.6 103.8 100.1 100.4 112.0 125.8 113.9 114.0 201.7 92.8 174.9 112.6 35.6 25.4 22.7 25.6 30.2 26.1 42.6 21.5 26.6 36.2 37.8 23.6 23.4 3.0 30.8 19.9 42.2 41.5 26.0 57.8 62.4 61.9 53.2 49.8 61.4 56.4 55.5 54.9 60.5 66.9 74.4 32.0 134.6 44.2 21.5 71.2 63.7 43.2 34.3 101.9 39.5 58.1 50.2 176.9 55.8 47.1 46.0 108.4 35.8 83.8 63.3 74.3 32.4 2.5 34.5 43.2 49.9 44.4 48.6 25.6 38.0 40.3 31.3 37.8 48.6 15.8 45.4 41.7 114.7 71.0 40.4 23.8 58.4 24.4 122.4 102.3 6.9 23.3 54.4 42.7 20.6 95.8 38.4 30.9 19.1 42.6 35.8 26.6 25.2 120.6 68.4 50.1 65.7 31.8 58.1 26.3 43.5 43.0 22.7 35.1 75.4 57.4 35.4 62.9 36.8 81.9 38.8 STAU2 39K2 ENSG00000040341 "Staufen double-stranded RNA binding protein 2" Q9NUL3 8 73420369-73747708 "Predicted intracellular proteins" Transport RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 278.9;Inhibitory neurons: 298.3;Oligodendrocyte precursor cells: 157.8;Oligodendrocytes: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 152.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019155, CAB020836" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB020836: , HPA019155: AB_1857565" "unprognostic (5.75e-2)" "unprognostic (3.39e-1)" "unprognostic (2.31e-3)" "unprognostic (2.47e-2)" "unprognostic (3.76e-1)" "unprognostic (6.27e-2)" "unprognostic (1.07e-2)" "unprognostic (1.18e-1)" "unprognostic (6.36e-2)" "unprognostic (4.01e-2)" "unprognostic (3.31e-2)" "unprognostic (1.89e-1)" "unprognostic (3.62e-3)" "unprognostic (9.94e-2)" "unprognostic (2.98e-1)" "unprognostic (6.44e-3)" "unprognostic (4.25e-2)" 20.2 22.7 24.8 15.8 30.5 24.6 17.8 35.0 39.6 15.3 5.5 17.6 14.9 18.2 19.0 35.1 16.6 24.2 70.6 34.8 22.8 29.5 25.7 17.3 19.3 25.3 25.6 18.2 16.1 29.6 12.5 17.6 25.0 20.9 18.6 34.6 20.5 20.8 110.6 15.0 20.8 23.4 16.2 16.7 16.3 16.8 20.7 35.0 22.9 110.0 22.0 20.8 14.2 35.3 34.7 40.7 63.5 34.5 35.5 25.2 19.3 30.4 27.5 27.1 35.4 15.6 36.0 55.1 31.5 23.9 24.3 27.2 44.5 29.2 39.1 56.1 21.2 74.7 19.4 25.5 18.6 28.4 25.8 18.1 21.6 23.2 15.1 55.8 54.8 48.2 50.5 24.2 36.8 22.6 152.7 22.5 31.4 57.5 26.8 44.9 29.6 46.3 57.6 38.1 24.0 40.2 16.4 43.1 27.4 46.8 51.2 33.3 43.4 26.3 46.0 26.2 22.7 39.4 41.7 51.8 29.3 42.3 22.1 24.4 18.0 42.8 28.6 17.9 21.5 15.7 19.0 24.3 18.4 17.9 16.6 21.7 30.8 44.4 22.8 25.1 26.0 12.8 24.8 30.5 35.0 39.6 34.8 22.8 25.3 25.6 25.0 16.2 20.7 35.3 20.4 9.6 31.1 120.8 22.5 10.6 15.4 16.7 8.6 29.1 24.6 11.8 75.7 21.5 40.7 20.2 41.7 18.4 27.1 22.5 43.0 22.7 22.0 18.6 11.6 26.2 29.9 14.7 278.9 21.7 10.0 20.2 21.4 25.5 20.3 21.8 38.2 58.0 16.1 28.6 298.3 17.6 18.3 24.1 16.8 32.2 9.0 22.5 16.0 129.3 16.9 26.9 43.3 157.8 149.9 17.6 16.5 9.4 20.2 10.9 102.1 37.6 27.6 22.2 0.0 15.8 21.8 12.5 13.8 22.1 19.2 12.2 21.6 20.5 16.1 18.5 STUB1 "CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1" ENSG00000103266 "STIP1 homology and U-box containing protein 1" Q9UNE7 16 680224-682870 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037202, CAB037209, HPA041222, HPA043531" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "CAB037202: AB_1840759, CAB037209: AB_1840757, HPA041222: AB_2677368, HPA043531: AB_2678533" "unprognostic (5.70e-2)" "unprognostic (2.53e-1)" "unprognostic (1.90e-1)" "unprognostic (3.89e-1)" "unprognostic (9.00e-2)" "unprognostic (3.06e-1)" "unprognostic (4.09e-3)" "unprognostic (2.21e-1)" "unprognostic (2.23e-1)" "unprognostic (8.31e-2)" "unprognostic (5.78e-2)" "unprognostic (6.77e-2)" "prognostic favorable (6.49e-9)" "unprognostic (9.67e-2)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-1)" 80.2 126.3 185.5 35.6 186.9 48.9 76.0 183.8 242.7 74.8 173.1 100.3 50.7 67.0 60.3 86.8 65.3 42.1 151.1 187.3 185.3 91.4 100.7 65.0 52.5 188.2 184.2 65.7 93.7 90.6 93.7 23.9 187.9 80.2 32.6 33.2 86.6 53.5 201.8 111.7 63.1 40.1 180.6 70.0 86.2 45.1 193.5 42.3 72.9 125.2 38.2 80.7 69.1 188.0 81.6 107.6 59.4 108.0 123.4 102.5 43.8 112.8 95.1 100.9 90.5 131.0 97.1 83.0 78.2 147.5 69.1 69.7 73.0 137.3 42.9 93.6 318.8 53.4 154.1 104.7 183.7 85.9 96.4 141.1 134.3 118.2 71.4 76.3 106.2 72.3 87.1 119.2 149.3 318.4 90.1 85.4 76.4 107.1 127.5 143.5 46.8 200.6 132.5 72.6 121.1 103.4 89.4 165.8 137.1 35.9 114.1 147.8 108.7 104.3 99.8 94.3 125.9 137.6 150.2 132.3 83.8 73.9 122.0 17.7 13.6 21.7 15.7 12.9 14.5 19.6 13.5 13.8 12.1 21.0 12.8 11.6 13.4 11.2 13.9 20.7 13.2 7.2 185.5 186.9 183.8 242.7 187.3 185.3 188.2 184.2 187.9 180.6 193.5 188.0 96.2 38.5 27.9 24.5 88.9 114.7 107.2 63.9 83.1 93.3 137.1 158.7 1.0 104.4 52.4 130.6 52.1 80.1 101.4 142.7 285.7 139.6 8.6 82.8 69.6 71.6 76.0 68.5 23.2 169.7 93.8 85.7 68.3 65.0 21.0 97.9 80.3 122.1 113.1 84.1 21.1 101.4 85.5 69.4 94.9 16.7 109.0 79.0 117.4 15.0 154.4 184.3 110.2 14.1 24.8 190.2 110.8 112.1 108.6 160.8 165.5 324.1 61.2 83.9 72.3 82.3 129.7 50.4 62.4 107.0 120.5 100.7 96.2 132.5 109.3 118.8 TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 87.9;Proximal enterocytes: 81.2;Proximal tubular cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" 12.8 18.6 16.6 8.2 17.4 8.3 10.9 18.9 18.4 8.8 17.7 17.8 18.9 11.1 9.7 13.4 9.3 5.5 42.3 16.5 17.5 30.1 69.2 7.7 10.4 17.4 17.4 8.3 12.0 18.2 9.5 8.3 17.3 9.5 16.1 9.4 11.4 9.2 61.5 11.3 16.7 9.7 16.9 11.5 15.1 12.1 17.6 9.9 9.4 55.9 12.2 11.8 9.2 16.7 39.6 61.2 19.4 20.2 16.5 23.5 25.7 28.5 26.8 56.2 44.4 40.5 23.2 32.6 21.2 33.1 38.9 35.8 43.0 41.5 52.6 17.3 58.1 32.0 29.8 72.3 45.5 38.3 21.7 29.0 28.6 48.5 51.1 20.9 29.6 24.2 44.4 24.1 26.6 71.6 44.7 28.7 16.8 42.5 62.9 28.1 47.7 40.8 33.2 27.6 29.5 32.4 19.6 64.0 55.3 25.3 53.3 29.1 26.4 39.9 29.9 27.5 50.7 25.9 27.2 38.7 30.4 26.0 29.6 2.2 9.4 9.0 9.8 8.5 10.7 7.5 13.7 9.7 10.6 9.9 12.4 10.3 1.4 17.8 7.4 7.0 10.2 9.4 16.6 17.4 18.9 18.4 16.5 17.5 17.4 17.4 17.3 16.9 17.6 16.7 9.8 3.2 6.3 2.6 12.0 2.5 8.0 21.1 8.6 8.2 7.8 10.9 54.0 17.2 11.5 14.7 2.1 32.1 8.2 32.9 54.8 29.1 15.3 8.0 11.4 14.2 13.8 17.4 4.0 27.4 28.9 14.1 16.8 6.4 9.5 16.2 8.6 87.9 26.3 6.7 3.9 21.7 12.2 10.7 3.9 46.0 11.8 9.2 10.6 2.8 22.0 15.5 14.4 1.5 3.2 30.0 25.8 11.3 10.7 11.6 81.2 109.7 9.1 13.4 19.7 10.7 14.6 26.8 13.9 18.6 4.3 19.8 10.1 40.7 32.8 7.1 TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 114.7;Late spermatids: 163.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "Nucleoplasm, Cytosol" "HPA042567: AB_2678055" "unprognostic (2.34e-1)" "unprognostic (5.84e-2)" "unprognostic (1.41e-2)" "prognostic favorable (9.75e-4)" "unprognostic (2.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-3)" "unprognostic (1.54e-1)" "unprognostic (6.30e-2)" "prognostic favorable (5.34e-4)" "unprognostic (7.07e-2)" "prognostic favorable (8.52e-4)" "unprognostic (9.00e-2)" "unprognostic (8.52e-2)" "unprognostic (7.25e-3)" "prognostic favorable (4.18e-4)" 7.4 15.1 17.5 6.0 18.6 25.7 10.0 17.3 22.3 8.2 15.1 8.9 6.4 10.0 9.2 6.1 9.5 6.7 9.1 17.1 17.0 12.4 30.5 11.9 9.6 18.6 17.4 8.1 8.1 13.0 8.5 6.8 18.4 7.4 8.2 24.7 7.6 6.4 35.5 7.7 7.5 9.3 17.4 8.5 7.9 11.1 17.5 12.2 11.5 19.9 8.1 7.6 6.9 19.5 4.9 3.6 6.0 7.0 8.9 6.8 2.5 7.8 6.0 7.4 8.1 4.9 8.5 31.7 8.3 5.0 10.8 4.0 5.2 4.0 9.3 2.9 6.3 6.2 5.0 5.2 8.4 12.6 6.2 4.2 7.7 7.3 5.3 9.1 3.8 19.3 9.7 14.5 7.2 3.5 18.7 10.1 4.0 9.3 8.4 45.0 8.4 5.8 12.0 5.1 10.0 8.0 7.4 6.2 9.5 4.1 11.5 12.3 7.1 6.2 4.1 4.2 10.3 13.9 12.2 24.2 12.4 30.9 7.3 1.1 0.3 0.0 0.2 0.2 0.0 1.0 0.7 0.4 0.5 2.5 0.9 0.7 0.6 0.3 0.3 0.8 0.5 0.3 17.5 18.6 17.3 22.3 17.1 17.0 18.6 17.4 18.4 17.4 17.5 19.5 12.0 32.1 62.6 47.3 20.2 9.1 6.3 4.2 4.0 24.5 15.0 9.9 14.3 10.0 8.7 7.3 114.7 4.2 16.2 11.1 3.9 6.7 79.0 14.2 12.6 12.8 14.4 16.6 42.6 8.2 3.1 10.2 8.6 12.0 2.5 17.5 8.6 46.0 4.2 70.7 43.6 9.8 4.1 10.3 18.9 163.1 9.9 11.1 16.0 45.0 6.5 33.1 8.2 60.8 68.2 9.5 9.4 15.1 8.9 7.1 10.7 8.7 14.4 62.4 6.6 17.0 11.5 33.3 5.7 7.1 8.0 7.0 10.8 16.5 9.0 6.6 TATDN3 ENSG00000203705 "TatD DNase domain containing 3" Q17R31 1 212791828-212816830 "Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032092 Approved Approved "Nucleoplasm,Golgi apparatus,Focal adhesion sites" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Golgi apparatus, Focal adhesion sites" "HPA032092: AB_10671086" "unprognostic (9.81e-2)" "unprognostic (1.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.17e-1)" "unprognostic (1.46e-1)" "unprognostic (1.74e-1)" "unprognostic (9.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.80e-1)" "unprognostic (3.88e-2)" "unprognostic (3.34e-3)" "unprognostic (5.02e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.93e-1)" "unprognostic (2.44e-1)" "unprognostic (3.13e-3)" "unprognostic (2.96e-3)" 13.0 11.3 10.1 10.4 12.4 12.2 10.0 10.1 12.7 6.5 9.3 8.3 6.1 7.1 13.3 7.3 7.7 7.4 19.3 10.6 12.4 16.6 10.3 8.0 12.2 12.2 10.5 8.6 9.4 18.2 8.2 7.3 12.4 6.9 7.7 17.7 8.5 6.9 29.9 6.3 7.2 7.7 10.5 11.1 11.1 10.0 10.4 11.2 11.7 24.1 10.3 8.2 5.5 15.8 12.2 11.9 10.3 15.1 16.7 26.0 23.5 12.9 14.3 10.8 13.1 3.1 17.2 27.4 12.3 12.4 6.0 7.6 13.0 18.2 11.5 17.1 17.0 13.4 10.3 6.3 19.0 33.3 16.3 20.6 12.8 14.3 37.3 11.2 16.1 37.7 28.2 21.7 11.7 5.9 28.4 10.9 13.9 14.9 7.6 16.0 19.3 49.4 11.3 6.3 21.6 18.5 14.5 25.1 30.6 19.2 26.6 19.6 10.1 7.9 10.3 16.4 13.0 19.4 32.9 44.9 20.6 26.8 12.0 26.1 37.2 60.2 12.7 59.3 11.5 39.7 15.8 15.4 45.6 31.0 12.5 14.9 42.8 13.8 64.4 74.6 16.1 22.9 10.1 12.4 10.1 12.7 10.6 12.4 12.2 10.5 12.4 10.5 10.4 15.8 9.1 6.4 16.2 17.3 18.5 4.5 8.1 14.2 3.4 16.1 8.5 8.3 36.6 8.6 8.0 3.7 18.8 14.3 39.7 3.4 41.1 18.1 12.2 10.8 7.6 8.9 10.2 6.5 35.1 16.5 17.5 10.0 6.1 7.8 7.0 10.8 5.3 7.0 18.8 15.2 43.9 5.1 12.2 27.6 8.3 4.0 5.3 20.4 14.2 17.8 31.0 17.8 8.2 23.1 53.6 12.0 6.2 4.9 9.3 6.2 7.3 26.4 12.5 29.6 6.6 8.8 9.2 24.2 17.9 6.6 4.4 9.3 11.1 11.0 5.2 7.0 TBC1D14 KIAA1322 ENSG00000132405 "TBC1 domain family member 14" Q9P2M4 4 6909242-7033118 "Plasma proteins, Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 197.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036930, HPA067398" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA036930: AB_10670155, HPA067398: AB_2685833" "unprognostic (3.05e-2)" "unprognostic (7.48e-3)" "unprognostic (4.80e-3)" "unprognostic (8.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.78e-3)" "unprognostic (9.63e-2)" "unprognostic (5.25e-2)" "unprognostic (9.71e-2)" "unprognostic (7.65e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" "prognostic favorable (5.28e-10)" "unprognostic (1.56e-1)" "unprognostic (3.50e-1)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" 26.3 42.1 42.7 31.5 41.9 15.9 27.6 38.7 43.9 19.4 50.2 26.4 22.8 20.9 22.9 34.0 23.5 17.0 30.4 42.9 44.9 44.5 27.4 24.4 29.8 49.3 45.6 28.7 19.5 41.9 27.1 23.8 44.8 24.5 26.3 18.5 31.7 20.2 51.6 49.5 26.0 22.9 45.7 34.9 58.5 30.0 48.7 40.1 19.2 41.3 26.9 19.8 22.2 44.2 34.5 36.8 40.4 45.5 32.8 27.4 24.5 27.0 29.3 24.7 21.1 38.3 69.8 54.9 15.6 32.5 62.8 24.5 68.4 61.7 30.0 15.5 22.2 91.8 23.8 40.4 22.7 42.0 197.9 21.3 85.8 23.4 38.3 31.5 23.5 51.2 88.6 19.3 30.2 22.3 64.9 42.5 54.9 41.1 40.8 80.2 53.2 59.9 36.8 23.9 61.6 44.0 22.4 24.1 84.3 31.2 33.3 39.4 23.7 27.2 20.5 24.0 40.3 36.7 91.6 55.7 25.4 53.2 26.6 2.6 13.2 5.6 8.6 8.2 13.1 8.1 9.3 9.3 10.7 8.3 6.9 6.6 40.6 8.6 3.9 11.5 11.9 10.8 42.7 41.9 38.7 43.9 42.9 44.9 49.3 45.6 44.8 45.7 48.7 44.2 8.4 6.4 17.7 22.5 15.5 9.1 7.0 15.8 15.9 10.2 21.1 16.3 4.6 10.0 14.8 14.7 14.6 12.5 16.3 17.7 19.6 11.5 68.0 12.3 10.3 7.8 6.6 7.2 25.6 10.2 7.1 9.5 14.8 11.9 7.6 18.9 8.2 24.4 26.0 25.2 25.1 15.7 10.2 33.6 8.7 41.0 7.2 27.8 19.6 27.2 24.4 13.4 16.5 51.8 27.0 11.8 14.2 8.6 15.4 12.9 12.8 19.8 10.7 6.6 0.0 12.7 7.1 17.7 18.0 19.8 11.9 16.4 16.3 12.5 19.9 10.1 TBC1D25 OATL1 ENSG00000068354 "TBC1 domain family member 25" Q3MII6 X 48539714-48562609 "Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 36.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029197 Approved Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029197: AB_2672945" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (5.12e-3)" "unprognostic (1.19e-1)" "unprognostic (9.18e-3)" "unprognostic (1.73e-2)" "unprognostic (1.32e-1)" "unprognostic (1.33e-1)" "unprognostic (7.29e-2)" "unprognostic (1.91e-1)" "unprognostic (2.57e-1)" "unprognostic (1.21e-1)" "unprognostic (8.07e-2)" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (8.75e-2)" 7.6 8.3 8.0 4.9 8.8 8.9 7.2 9.4 8.6 7.2 4.6 7.9 4.2 7.2 3.2 7.4 6.9 4.8 10.8 8.1 7.5 5.6 6.8 7.2 6.3 7.1 6.9 7.3 8.4 7.8 7.7 4.5 7.5 6.8 4.2 5.8 5.9 5.3 9.3 9.9 6.3 6.3 5.6 9.1 6.4 8.2 7.6 6.9 6.6 7.4 5.0 7.1 7.1 7.5 7.6 7.5 2.8 8.6 10.4 10.0 3.9 5.1 9.6 9.0 9.4 4.9 6.8 7.8 3.7 13.0 12.3 6.9 12.8 13.7 8.1 14.6 8.4 4.0 11.7 4.5 11.5 5.2 10.1 10.7 13.7 12.3 14.9 11.3 9.8 8.3 3.1 11.7 11.0 6.6 9.6 9.7 4.3 3.6 13.5 4.9 4.9 10.5 8.3 3.8 7.9 5.4 7.8 7.0 6.8 12.6 7.7 1.7 9.2 5.9 8.7 18.1 5.9 11.5 6.0 5.7 9.8 6.5 5.7 1.6 2.0 5.4 6.6 2.6 5.1 4.3 4.5 5.6 2.2 4.8 4.7 4.9 4.3 4.5 2.1 2.5 4.2 4.5 8.0 8.8 9.4 8.6 8.1 7.5 7.1 6.9 7.5 5.6 7.6 7.5 5.7 19.2 9.3 6.5 11.2 17.3 9.4 11.1 10.8 9.5 5.7 5.2 7.4 5.7 5.9 1.8 14.6 7.1 13.0 7.5 11.7 6.8 16.2 5.7 4.9 6.1 15.6 4.0 8.1 14.0 7.5 6.2 3.6 8.2 5.7 4.6 8.6 4.5 5.5 13.5 9.0 3.4 10.2 4.4 9.3 36.9 5.6 6.5 7.2 3.7 4.5 4.9 22.6 5.5 8.0 11.6 3.2 4.9 8.6 8.2 4.0 4.9 5.0 7.0 26.3 4.7 6.1 9.5 11.8 8.4 14.9 14.6 13.6 6.0 3.9 8.6 TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1013.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA 10000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.60e-4)" 102.7 162.6 189.0 43.1 201.7 74.2 100.4 220.8 237.5 156.8 216.5 78.5 106.1 53.2 103.2 373.2 87.1 49.7 78.4 180.1 200.0 112.2 133.9 67.8 55.7 209.6 191.2 80.9 105.5 306.1 78.7 68.0 212.2 85.7 59.3 82.8 222.3 83.5 366.3 263.5 95.9 36.7 207.6 75.4 81.7 182.7 199.9 65.8 92.7 209.6 85.3 51.6 185.9 230.2 220.5 162.1 149.5 169.6 214.7 97.2 156.9 62.8 175.2 196.3 242.9 225.3 246.2 113.8 127.4 134.2 152.4 328.8 158.1 254.3 84.0 192.3 165.9 193.7 225.4 254.6 129.7 139.5 143.7 144.9 201.8 174.3 96.1 98.4 93.7 169.2 128.9 391.5 104.0 289.3 170.1 248.3 155.6 556.1 227.6 154.4 96.1 521.1 275.1 115.8 183.2 113.0 103.1 278.4 139.6 77.2 151.3 274.4 55.2 160.5 66.8 141.0 212.6 118.4 119.8 122.7 163.8 212.6 162.2 55.6 72.7 52.5 137.8 106.4 148.8 100.1 180.1 159.1 124.2 99.1 207.1 164.5 32.7 183.7 83.9 137.1 290.1 170.9 189.0 201.7 220.8 237.5 180.1 200.0 209.6 191.2 212.2 207.6 199.9 230.2 60.4 73.7 71.1 47.7 87.6 169.5 227.5 297.9 125.7 90.8 161.1 155.6 52.9 120.1 221.5 165.5 123.0 509.5 88.1 159.2 56.7 166.2 443.9 102.2 40.1 64.7 100.0 80.1 15.3 225.1 525.5 81.8 89.7 64.2 36.1 90.1 73.2 143.1 188.0 112.7 19.2 144.0 199.4 113.8 99.3 1013.1 72.7 77.8 163.7 18.7 61.6 577.9 103.0 12.5 46.5 104.8 128.2 60.2 206.1 110.2 343.2 202.9 213.1 177.5 65.7 68.4 286.7 215.0 134.2 255.3 239.7 486.2 117.7 116.0 216.2 196.5 TEF KIAA1655 ENSG00000167074 "TEF transcription factor, PAR bZIP family member" Q10587 22 41367333-41399326 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 31.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (6.75e-2)" "unprognostic (5.24e-2)" "unprognostic (1.27e-2)" "unprognostic (2.57e-3)" "unprognostic (1.75e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.91e-3)" "unprognostic (7.87e-2)" "unprognostic (6.82e-3)" "unprognostic (2.12e-2)" "unprognostic (7.17e-3)" "prognostic favorable (3.47e-11)" "unprognostic (7.54e-2)" "unprognostic (2.87e-1)" "unprognostic (1.25e-1)" "unprognostic (6.55e-2)" 15.6 14.3 29.7 5.2 41.8 0.8 12.8 43.7 51.4 14.9 5.4 20.1 8.0 16.0 10.3 14.9 18.7 8.2 32.4 40.3 13.9 19.1 18.6 14.4 7.8 21.3 16.9 35.5 23.2 46.8 21.2 4.4 21.8 13.9 10.9 25.5 29.0 24.1 44.0 25.6 11.0 9.6 9.2 11.0 13.3 12.1 21.8 9.1 28.7 39.9 8.3 15.1 11.9 35.5 4.5 2.1 6.9 8.0 11.4 6.7 5.0 3.3 16.1 4.6 6.4 5.9 11.1 12.7 4.7 16.6 6.8 9.5 2.1 7.8 5.3 5.8 3.2 2.6 4.3 3.8 5.0 3.9 3.6 9.4 12.5 6.0 14.0 11.1 3.2 2.7 1.2 10.7 2.3 10.5 3.3 2.8 4.0 31.1 5.2 9.3 4.4 5.5 3.5 9.9 6.5 3.3 15.0 3.3 6.8 5.6 5.5 4.4 4.8 12.7 13.6 5.2 5.3 11.0 8.5 8.1 12.4 3.4 13.7 0.0 0.2 0.8 0.6 0.7 0.9 0.4 0.6 0.6 0.2 0.1 0.7 0.5 0.4 0.1 0.4 0.8 0.5 0.3 29.7 41.8 43.7 51.4 40.3 13.9 21.3 16.9 21.8 9.2 21.8 35.5 9.8 16.0 9.9 21.2 1.3 6.6 3.2 4.9 12.5 41.9 4.3 6.9 13.1 20.0 3.3 18.4 8.4 4.4 0.7 18.7 11.7 3.4 11.3 1.3 5.6 7.0 7.7 0.4 14.2 6.1 0.6 13.2 3.6 1.7 4.5 6.5 6.4 33.4 1.3 32.0 15.0 6.0 8.2 4.1 4.0 23.2 17.1 1.7 5.4 1.9 2.3 27.3 2.1 9.0 17.4 3.9 4.4 25.6 1.2 3.6 11.2 5.6 5.5 13.7 6.6 19.6 9.0 3.7 5.7 6.7 8.7 1.4 1.9 9.1 4.6 2.4 TEX2 "HT008, KIAA1738, TMEM96" ENSG00000136478 "Testis expressed 2" Q8IWB9 17 64147227-64263260 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5;Late spermatids: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020648, HPA057116" Approved Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA020648: AB_1857908, HPA057116: AB_2683341" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "prognostic favorable (3.90e-6)" "unprognostic (1.69e-2)" "unprognostic (3.84e-2)" "unprognostic (8.34e-2)" "unprognostic (6.97e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.53e-1)" "unprognostic (8.39e-2)" "unprognostic (1.11e-1)" "unprognostic (7.97e-2)" "unprognostic (7.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.53e-3)" "unprognostic (5.59e-3)" 16.6 24.2 38.4 7.3 46.9 18.7 19.6 38.3 39.3 17.8 31.1 13.6 10.2 14.7 11.4 17.3 13.4 16.7 27.2 37.6 46.2 18.5 33.2 14.9 6.3 43.5 46.4 15.7 29.4 31.5 11.2 9.9 43.3 16.3 13.5 23.0 19.4 17.0 45.0 15.5 10.2 14.6 40.4 12.7 13.2 53.5 44.9 8.9 40.2 41.9 6.8 10.5 11.1 44.2 32.6 15.2 9.5 19.5 44.7 26.3 11.5 44.1 49.7 39.2 27.0 14.2 7.8 11.3 11.0 55.9 24.3 15.5 17.0 53.3 44.7 16.6 11.6 76.3 9.9 27.0 16.7 22.5 12.2 19.3 29.0 26.7 54.3 27.5 19.1 18.8 21.3 13.6 29.8 36.1 20.5 10.4 5.4 25.3 26.9 12.6 85.8 16.1 22.7 14.9 14.4 24.0 21.9 55.9 24.3 52.2 26.4 19.0 22.6 36.5 21.1 28.5 25.8 14.0 20.1 7.2 14.5 21.0 33.6 0.0 3.1 0.9 1.5 1.0 1.7 0.3 1.7 1.8 2.9 0.6 1.7 1.7 0.3 3.3 2.0 20.6 1.3 1.8 38.4 46.9 38.3 39.3 37.6 46.2 43.5 46.4 43.3 40.4 44.9 44.2 8.1 3.2 8.1 27.4 3.4 8.8 6.8 5.1 16.5 4.2 17.6 13.7 33.3 8.6 6.2 12.9 6.2 2.5 14.7 10.7 1.9 4.7 53.5 6.0 10.5 8.8 12.1 15.4 41.6 8.3 2.0 7.4 16.3 4.2 3.8 12.2 8.6 30.4 12.0 10.1 35.6 11.3 6.1 11.5 3.7 52.9 6.5 9.2 7.2 17.8 2.9 7.2 1.0 33.2 39.3 6.5 4.6 12.8 10.1 7.1 7.1 8.3 8.2 17.3 0.0 12.6 7.4 22.5 8.8 14.6 8.9 1.4 3.6 9.4 10.9 5.4 THAP4 "CGI-36, Nb(III)" ENSG00000176946 "THAP domain containing 4" Q8WY91 2 241584405-241637158 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "DNA-binding, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 223.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044982, HPA053448" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear speckles" "HPA044982: AB_10959786, HPA053448: AB_2682154" "unprognostic (3.17e-2)" "unprognostic (1.70e-2)" "unprognostic (6.56e-2)" "unprognostic (1.36e-2)" "unprognostic (8.35e-2)" "unprognostic (7.23e-2)" "unprognostic (1.16e-3)" "unprognostic (3.61e-2)" "unprognostic (7.56e-2)" "unprognostic (2.18e-1)" "unprognostic (3.24e-1)" "unprognostic (2.21e-1)" "prognostic favorable (1.46e-4)" "unprognostic (2.57e-1)" "unprognostic (1.78e-1)" "unprognostic (5.06e-1)" "unprognostic (1.07e-1)" 34.3 31.8 60.3 19.0 60.4 28.1 35.6 57.7 78.5 34.5 60.2 51.1 42.1 30.9 28.7 53.1 29.0 25.0 106.5 58.9 60.7 96.7 54.0 29.3 22.0 60.0 61.4 33.2 48.4 107.0 37.7 16.1 60.3 43.7 27.1 9.0 42.1 24.1 118.8 46.8 34.9 17.3 56.3 26.5 52.0 40.8 62.7 23.4 31.9 91.6 19.0 41.5 38.9 59.8 47.6 53.4 31.5 58.9 41.5 43.1 53.7 32.1 42.5 46.6 41.4 48.6 41.1 40.5 16.4 50.1 53.8 53.4 63.8 71.4 17.6 33.3 76.9 42.5 35.7 138.7 55.0 48.6 28.5 44.8 55.4 50.2 69.2 32.5 43.9 62.4 76.9 13.1 36.4 84.5 51.1 110.1 57.1 43.9 45.2 55.9 44.1 52.6 100.2 57.0 76.4 50.1 24.7 76.9 65.1 19.4 38.7 52.3 40.0 55.5 36.6 50.7 58.3 32.4 19.9 42.6 40.2 40.4 40.9 31.0 15.7 40.3 27.4 18.0 29.4 21.6 30.3 25.5 16.4 25.0 28.6 23.3 10.2 22.7 24.1 23.2 53.6 16.1 60.3 60.4 57.7 78.5 58.9 60.7 60.0 61.4 60.3 56.3 62.7 59.8 16.6 19.2 21.7 15.7 16.4 20.0 42.1 31.9 21.1 9.9 21.2 17.1 55.9 35.8 28.3 40.5 4.2 23.4 13.2 64.6 223.0 48.0 17.7 37.5 19.6 17.7 28.8 21.5 12.2 27.8 24.6 19.9 35.2 58.9 7.0 16.6 13.6 38.0 17.7 8.4 12.8 52.3 32.6 11.4 10.6 7.7 18.0 14.2 12.4 7.5 15.3 11.1 22.6 11.1 11.5 27.6 44.2 19.5 21.3 38.1 79.0 90.0 21.3 6.8 32.9 16.3 23.3 25.3 29.1 40.0 25.9 27.5 15.1 17.5 60.2 53.4 THNSL2 "FLJ10916, SOFAT, TSH2" ENSG00000144115 "Threonine synthase like 2" Q86YJ6 2 88170295-88186636 "Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Proximal tubular cells: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 31.6;MCF7: 12.2;SK-MEL-30: 12.6;SuSa: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035395 Approved "Secreted - unknown location" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035395: AB_10601600" "unprognostic (1.51e-2)" "unprognostic (1.03e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (4.53e-2)" "unprognostic (8.73e-2)" "unprognostic (6.64e-2)" "unprognostic (7.26e-2)" "unprognostic (1.93e-1)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-2)" "unprognostic (2.01e-3)" "unprognostic (6.98e-2)" "unprognostic (8.81e-2)" "unprognostic (1.40e-1)" "unprognostic (1.24e-2)" 13.9 22.6 14.9 2.4 16.9 0.9 16.4 15.1 15.6 14.8 15.0 18.0 5.6 11.2 22.6 6.5 19.2 7.7 17.8 13.8 18.1 28.5 50.0 7.2 1.9 16.7 16.2 14.9 14.2 32.3 29.1 8.6 16.0 22.3 3.7 7.3 12.9 13.5 50.1 9.3 12.6 6.3 16.1 7.5 13.5 13.0 16.7 1.1 21.9 35.8 1.8 12.5 9.9 16.3 0.3 0.0 0.0 0.0 2.7 0.9 1.5 4.6 5.0 6.4 8.3 6.6 7.7 0.0 2.2 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.0 0.0 0.0 31.6 0.0 0.6 5.1 10.3 1.9 0.0 0.5 0.0 0.0 0.0 0.0 4.7 12.2 0.0 0.1 6.2 7.1 0.6 0.0 0.0 0.0 5.2 0.5 0.3 0.0 5.4 0.4 12.6 15.0 8.8 2.0 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.2 0.3 0.3 0.4 0.2 0.4 0.1 0.2 0.4 0.7 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 14.9 16.9 15.1 15.6 13.8 18.1 16.7 16.2 16.0 16.1 16.7 16.3 2.8 3.2 9.3 13.1 3.1 6.6 8.6 8.3 9.6 12.8 23.2 20.2 17.3 20.0 2.9 14.7 0.0 42.5 0.4 9.2 58.7 14.8 1.3 14.5 8.9 3.6 2.4 6.1 2.8 3.0 15.7 13.8 6.6 8.4 0.0 8.1 7.9 43.6 4.6 13.5 3.0 6.8 4.1 10.7 4.6 4.2 9.0 2.8 14.2 5.6 11.3 43.5 3.1 4.0 16.7 5.4 8.9 9.8 1.7 6.3 13.4 87.2 5.2 7.3 0.0 8.9 6.4 3.7 11.4 3.7 5.1 23.9 1.7 13.8 6.2 5.6 THUMPD2 "C2orf8, MGC2454" ENSG00000138050 "THUMP domain containing 2" Q9BTF0 2 39736060-39779267 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043042, HPA058025" Approved Uncertain Nucleoplasm Yes No "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA043042: AB_10964424, HPA058025: " "unprognostic (6.30e-2)" "unprognostic (9.12e-3)" "unprognostic (2.48e-2)" "unprognostic (4.62e-3)" "unprognostic (2.16e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.22e-1)" "unprognostic (2.31e-2)" "unprognostic (1.30e-1)" "unprognostic (2.72e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-3)" 2.4 2.0 2.6 0.5 2.5 1.7 2.1 2.9 3.0 1.9 2.6 1.9 0.5 1.7 0.2 3.5 1.5 0.5 3.3 2.6 2.6 2.4 2.3 2.2 1.4 2.6 2.8 3.2 2.2 0.5 2.3 0.4 2.6 2.0 0.7 0.4 2.1 0.4 6.0 2.5 2.0 0.4 2.4 2.5 2.2 0.9 2.6 2.0 2.1 4.0 1.5 2.1 2.4 2.8 4.9 4.7 1.0 6.5 2.3 3.3 2.7 1.3 2.5 3.0 3.1 5.0 4.5 7.8 2.7 1.6 7.6 2.0 9.7 4.4 3.2 13.1 10.8 4.7 3.0 5.7 4.1 6.3 2.4 3.9 3.2 3.1 1.0 2.9 4.9 1.5 5.9 1.8 6.1 2.3 3.3 5.0 0.0 13.0 2.9 3.4 4.2 5.4 2.9 2.6 5.7 3.1 1.3 5.6 3.2 0.4 1.8 3.9 2.5 4.0 2.5 1.1 3.6 2.4 3.1 5.1 2.0 11.4 3.2 0.0 0.6 0.0 0.1 0.4 0.6 0.7 0.4 0.1 0.5 0.3 0.6 0.4 0.1 0.4 0.1 0.9 0.1 0.6 2.6 2.5 2.9 3.0 2.6 2.6 2.6 2.8 2.6 2.4 2.6 2.8 17.4 25.6 20.6 26.8 17.8 14.3 29.0 19.5 15.9 26.8 14.4 29.8 23.7 8.6 20.3 14.7 18.8 11.5 23.0 7.2 19.6 16.6 4.5 7.5 16.9 13.7 9.6 23.8 42.2 13.7 13.6 18.4 17.9 10.9 7.0 19.2 10.0 9.9 11.3 6.7 41.6 8.1 8.2 10.9 7.7 4.0 28.0 10.0 5.4 45.0 11.8 12.1 15.5 45.2 30.3 16.7 17.1 25.6 8.2 23.7 10.3 16.4 10.9 21.1 6.6 20.5 16.0 9.1 19.7 16.9 13.5 6.8 12.6 22.2 13.5 22.7 TIMM10 "TIM10, TIM10A, TIMM10A" ENSG00000134809 "Translocase of inner mitochondrial membrane 10" P62072 11 57528464-57530803 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 284.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039946 Supported Enhanced Mitochondria NA NA 16000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039946: AB_10673023" "unprognostic (9.34e-3)" "unprognostic (1.16e-2)" "unprognostic (2.21e-1)" "unprognostic (2.01e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-2)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (3.40e-3)" "unprognostic (7.62e-2)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (9.87e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-2)" "unprognostic (2.15e-2)" 40.5 41.6 55.1 28.5 56.9 34.8 42.5 56.3 68.3 24.8 53.2 35.5 27.0 27.2 43.8 44.1 25.1 20.3 60.9 56.7 57.4 50.7 77.6 27.9 45.8 55.8 55.6 25.5 33.6 45.1 29.2 21.7 56.1 31.0 35.9 15.1 28.0 30.2 77.8 33.7 27.8 27.5 58.5 37.9 35.3 35.6 56.1 38.5 29.7 67.7 50.1 33.7 27.2 58.0 115.6 171.9 79.1 76.0 67.6 57.2 99.7 96.6 77.0 151.1 85.9 127.6 97.9 218.1 108.0 86.5 131.4 86.3 114.0 112.6 136.4 74.8 84.9 139.4 67.0 167.5 71.3 183.3 148.0 54.2 89.6 146.1 101.4 40.0 95.2 142.8 157.1 96.7 112.7 241.1 99.4 243.5 83.4 99.9 184.4 163.5 167.0 190.3 77.6 78.2 64.0 82.2 101.5 198.6 128.6 77.7 150.1 69.3 60.2 86.0 160.5 150.6 188.1 133.2 192.6 176.1 79.2 91.3 146.2 30.9 88.3 20.9 71.5 84.2 81.6 187.6 86.4 79.0 146.4 179.0 118.0 103.6 4.9 67.3 81.3 146.6 84.0 145.1 55.1 56.9 56.3 68.3 56.7 57.4 55.8 55.6 56.1 58.5 56.1 58.0 53.2 12.8 11.0 3.9 66.4 122.9 42.9 94.5 54.1 16.9 103.1 142.2 124.1 78.6 45.6 44.1 4.2 68.0 52.5 78.2 211.3 84.1 134.7 36.7 28.1 55.8 27.0 56.8 3.2 125.6 88.2 42.0 24.5 39.1 52.6 30.1 40.4 212.3 125.9 8.4 3.9 61.0 48.8 71.7 100.3 284.7 46.3 52.9 81.8 3.7 103.2 55.0 56.7 3.0 5.6 85.3 63.5 51.1 51.5 102.4 120.3 227.3 23.2 15.5 13.1 50.5 71.3 85.9 52.8 78.1 129.7 39.5 42.2 37.7 92.6 52.4 TIMM17B "DXS9822, JM3" ENSG00000126768 "Translocase of inner mitochondrial membrane 17B" O60830 X 48893447-48898143 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029093 Approved Approved Microtubules,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Microtubules Mitochondria "HPA029093: AB_10600913" "unprognostic (7.87e-2)" "prognostic favorable (6.63e-4)" "unprognostic (8.44e-2)" "unprognostic (3.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-3)" "unprognostic (1.44e-1)" "unprognostic (2.01e-1)" "unprognostic (1.14e-2)" "unprognostic (2.04e-1)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (9.40e-2)" "unprognostic (5.24e-3)" "unprognostic (8.67e-2)" "prognostic favorable (7.88e-4)" 24.0 42.0 49.8 18.8 51.1 28.2 25.9 50.6 60.6 29.2 47.0 40.3 25.5 27.7 21.0 38.2 29.1 17.6 75.3 50.1 49.6 47.5 48.7 28.1 27.8 49.5 48.9 27.3 33.4 47.6 45.1 23.0 48.9 36.4 19.4 26.2 25.3 27.7 99.1 35.4 32.2 18.0 50.5 37.9 40.5 18.7 50.6 40.7 30.4 83.2 26.8 35.5 28.7 53.1 71.0 127.8 78.7 78.1 24.2 19.3 65.4 31.3 47.7 81.1 52.9 113.3 93.4 51.8 47.4 27.2 131.1 52.5 125.1 68.3 30.4 111.2 140.1 37.6 69.2 101.4 68.3 56.5 35.0 24.9 67.3 60.9 80.8 40.3 37.6 90.1 56.5 118.2 37.8 183.5 89.4 136.7 102.8 93.2 118.3 62.1 51.0 187.8 80.9 41.1 77.6 69.7 48.6 77.0 47.0 98.5 168.7 97.4 26.2 37.1 72.4 89.8 54.9 107.8 137.1 64.3 51.4 100.3 44.6 178.2 123.4 179.9 67.2 123.9 77.4 113.4 67.1 76.3 121.1 113.4 64.8 59.7 139.6 75.7 104.8 127.6 74.4 124.3 49.8 51.1 50.6 60.6 50.1 49.6 49.5 48.9 48.9 50.5 50.6 53.1 23.8 25.6 34.9 4.9 56.5 30.2 52.4 99.0 21.1 40.4 52.9 62.2 40.0 41.5 59.4 73.5 16.7 94.4 45.0 40.2 185.9 94.5 5.6 42.4 25.5 24.6 81.5 48.8 4.3 73.1 94.3 31.0 34.1 37.8 52.0 50.3 24.7 56.0 99.6 35.3 5.6 68.3 91.6 37.6 49.8 7.4 23.9 48.9 44.4 3.7 85.9 48.7 55.6 2.5 9.1 89.9 92.7 23.0 103.7 63.3 102.4 160.0 56.6 43.8 32.9 21.2 45.0 29.0 39.9 52.0 34.4 79.6 48.2 52.7 59.8 61.2 TIMM21 "C18orf55, HSPC154, TIM21" ENSG00000075336 "Translocase of inner mitochondrial membrane 21" Q9BVV7 18 74148523-74160531 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010587, HPA051543" Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA010587: AB_1851244, HPA051543: AB_2681528" "unprognostic (4.88e-1)" "unprognostic (2.20e-2)" "unprognostic (1.16e-1)" "unprognostic (8.61e-2)" "unprognostic (3.81e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (9.22e-5)" "unprognostic (1.42e-1)" "unprognostic (1.59e-2)" "unprognostic (1.93e-2)" "unprognostic (4.79e-3)" "unprognostic (1.55e-3)" "prognostic favorable (1.38e-9)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.66e-2)" 13.8 14.6 22.7 10.1 23.8 8.1 10.6 25.7 29.6 9.7 23.0 16.2 12.2 10.4 11.9 13.3 9.5 5.6 48.7 22.8 23.2 21.0 22.3 7.4 9.9 22.9 22.5 11.9 9.6 18.0 11.4 10.0 23.0 12.2 13.5 14.8 10.2 9.9 50.8 11.1 11.5 9.5 22.6 13.8 12.4 7.0 23.1 7.7 12.4 47.9 10.1 12.6 10.2 24.3 25.6 26.6 24.4 30.2 19.7 17.4 35.9 38.5 12.8 22.8 19.2 19.5 18.3 34.2 12.1 15.0 19.1 41.6 34.0 32.8 38.1 21.7 19.6 14.7 46.2 53.9 10.0 55.6 23.7 16.2 19.4 29.0 19.9 18.6 17.5 19.0 30.2 23.2 27.9 25.6 29.6 45.6 23.5 15.3 48.6 27.5 28.2 42.6 30.2 35.5 25.9 14.2 14.5 35.9 23.8 19.1 24.9 28.6 12.6 53.3 37.9 17.5 40.3 7.3 60.3 37.2 26.0 59.7 38.0 8.7 9.8 6.3 12.7 15.6 15.2 16.0 12.2 10.7 13.2 12.3 15.3 17.6 1.2 17.1 18.2 15.7 10.0 8.8 22.7 23.8 25.7 29.6 22.8 23.2 22.9 22.5 23.0 22.6 23.1 24.3 8.0 12.8 17.8 8.1 12.1 8.0 9.3 30.2 21.6 17.1 9.0 12.6 165.5 14.3 16.7 5.5 6.2 29.4 10.2 9.4 54.8 13.2 3.1 7.3 13.5 13.1 14.4 16.2 8.6 9.4 28.3 19.0 14.8 6.7 9.5 12.6 11.7 20.2 18.8 16.8 11.1 11.5 8.2 11.7 3.5 1.5 11.5 8.5 1.8 6.5 13.4 20.0 9.2 8.5 9.2 9.1 6.2 12.4 25.7 10.5 12.5 34.5 15.0 20.1 6.6 15.0 16.5 12.8 12.7 20.2 8.0 16.4 7.5 12.9 18.2 7.7 TIMM22 "TEX4, TIM22" ENSG00000177370 "Translocase of inner mitochondrial membrane 22" Q9Y584 17 997129-1003671 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "basophil: 4.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045138 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA045138: AB_10962055" "unprognostic (2.69e-1)" "unprognostic (3.42e-1)" "unprognostic (2.57e-1)" "unprognostic (8.69e-3)" "unprognostic (3.00e-2)" "unprognostic (2.75e-2)" "unprognostic (2.16e-2)" "unprognostic (9.36e-2)" "unprognostic (2.37e-1)" "unprognostic (1.80e-1)" "prognostic favorable (3.42e-4)" "unprognostic (1.27e-1)" "prognostic favorable (1.41e-4)" "unprognostic (2.45e-1)" "unprognostic (3.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.70e-3)" 7.7 9.9 6.6 3.9 7.0 6.8 7.5 9.7 8.6 6.8 8.4 8.5 2.8 7.5 8.8 8.8 6.4 1.6 15.2 6.4 6.8 9.3 6.3 6.2 3.8 7.4 6.8 7.3 7.0 10.3 9.0 6.9 8.1 7.0 4.4 4.5 7.2 1.8 12.3 8.5 6.2 5.2 7.4 7.3 8.4 6.9 7.4 6.2 6.6 12.2 6.0 7.9 6.7 8.3 3.9 0.2 13.0 12.6 19.0 8.8 4.0 12.8 8.5 10.6 13.1 8.4 4.8 4.7 2.5 21.2 9.1 3.6 26.0 14.2 21.0 0.0 0.0 9.5 1.8 0.1 18.6 5.6 1.5 11.3 9.0 13.4 20.6 10.6 17.2 0.3 1.8 13.1 12.9 0.0 17.2 6.6 9.0 11.5 17.0 8.9 6.5 6.5 17.1 0.2 4.6 10.7 4.9 5.3 10.3 12.3 8.1 10.0 18.7 12.5 9.5 10.2 15.7 2.9 0.0 4.2 10.2 8.6 12.4 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 7.0 9.7 8.6 6.4 6.8 7.4 6.8 8.1 7.4 7.4 8.3 20.2 3.2 15.9 2.0 21.7 43.6 10.7 31.5 17.1 26.4 21.4 18.5 25.3 18.6 17.8 7.3 33.3 62.8 16.3 11.8 37.2 36.2 5.9 14.9 21.2 28.2 20.4 16.8 6.9 28.2 60.8 26.9 17.3 15.8 3.8 27.1 13.9 12.1 40.4 26.9 7.1 11.9 30.5 9.7 18.9 9.7 20.2 14.6 16.0 7.5 26.9 19.1 24.7 4.0 2.8 29.0 8.6 21.4 13.2 17.0 14.2 26.7 10.2 43.7 13.1 17.4 21.4 42.7 47.2 19.5 54.1 61.6 19.0 42.7 16.8 12.9 TIMM23 TIM23 ENSG00000265354 "Translocase of inner mitochondrial membrane 23" O14925 10 45972489-46003742 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA031408 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA031408: AB_10600828" "unprognostic (4.09e-2)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" "unprognostic (1.15e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "prognostic favorable (6.79e-4)" "unprognostic (4.41e-2)" "unprognostic (7.30e-2)" "unprognostic (3.24e-1)" "unprognostic (7.78e-2)" "unprognostic (5.54e-2)" "unprognostic (7.20e-2)" "unprognostic (2.21e-1)" 39.0 50.1 47.1 35.5 48.7 66.4 38.3 50.3 62.9 28.2 55.6 40.1 56.5 26.8 61.9 43.1 28.0 31.7 84.9 49.1 51.6 59.5 74.2 26.6 36.4 50.7 51.5 20.6 32.2 50.5 35.0 35.2 52.3 34.6 39.9 42.9 32.5 36.9 128.5 35.7 37.7 37.6 49.9 25.6 32.8 80.6 50.5 40.0 43.3 134.5 45.4 53.0 27.1 49.0 162.6 167.5 108.7 110.3 88.5 82.4 106.1 130.6 156.1 155.6 164.0 212.8 125.4 144.1 105.7 138.6 111.3 136.1 168.0 139.9 153.3 108.0 165.6 92.1 120.8 231.7 142.2 173.1 98.7 99.4 122.3 133.4 188.0 64.7 146.1 123.0 166.0 78.8 138.7 162.7 155.5 239.0 131.7 119.0 51.8 118.6 105.0 105.5 177.6 111.8 127.3 117.0 72.8 159.4 132.8 83.8 168.7 102.1 108.1 74.8 130.6 96.8 188.9 83.6 148.9 203.2 139.3 246.7 63.9 54.8 98.1 54.3 73.1 131.1 75.7 82.1 70.0 79.1 111.2 79.8 62.5 69.5 22.8 79.1 118.6 92.2 85.8 129.5 47.1 48.7 50.3 62.9 49.1 51.6 50.7 51.5 52.3 49.9 50.5 49.0 13.3 9.6 22.2 10.7 19.4 21.9 18.1 32.7 15.9 14.3 16.0 11.9 97.5 30.0 24.4 12.9 8.4 42.1 17.0 16.1 45.0 40.4 101.5 26.6 20.8 18.3 10.2 43.3 19.1 30.1 47.7 24.8 20.9 23.8 27.8 14.2 13.2 27.3 34.5 0.0 18.6 16.5 36.7 16.0 15.8 35.0 17.7 18.9 23.2 12.2 29.3 23.0 20.6 14.6 19.6 36.7 14.7 11.7 36.0 20.3 22.3 61.0 26.9 10.4 6.6 13.1 26.0 148.7 48.4 38.7 21.6 35.6 16.6 17.0 25.6 22.4 TIMM44 TIM44 ENSG00000104980 "Translocase of inner mitochondrial membrane 44" O43615 19 7926718-7943667 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043052, HPA073108" Supported Enhanced Mitochondria NA NA 9100 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043052: AB_10795713, HPA073108: " "unprognostic (1.75e-1)" "unprognostic (7.44e-3)" "unprognostic (2.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-2)" "unprognostic (5.81e-3)" "unprognostic (8.78e-2)" "unprognostic (2.42e-1)" "unprognostic (8.81e-2)" "unprognostic (2.07e-3)" "unprognostic (8.93e-2)" "unprognostic (1.80e-2)" "unprognostic (6.01e-2)" "unprognostic (6.43e-2)" "unprognostic (2.07e-2)" "unprognostic (4.18e-2)" 15.2 25.1 16.1 11.2 15.2 8.4 13.0 15.9 22.8 20.2 16.3 27.6 16.9 18.3 7.0 20.9 13.9 6.8 52.3 15.8 15.4 20.0 34.6 10.7 11.1 15.4 15.2 16.2 17.6 13.5 14.4 8.3 15.6 17.5 8.2 4.2 14.0 11.6 62.1 15.7 14.3 10.2 16.6 19.4 20.8 11.0 17.6 7.7 13.8 49.2 8.1 20.1 15.3 16.2 64.5 37.2 24.4 52.0 28.6 28.6 33.3 34.9 26.6 43.8 39.6 82.5 18.1 98.5 45.5 27.5 37.3 46.6 75.7 38.4 21.7 45.5 98.7 53.6 31.4 70.1 72.4 66.3 21.9 31.6 60.1 37.0 53.5 19.4 30.4 53.3 97.2 55.7 20.7 58.5 59.2 53.7 61.3 61.8 116.8 60.4 35.6 68.8 24.9 42.0 46.2 28.3 39.0 50.5 112.8 19.3 29.7 64.4 19.6 30.1 40.2 69.7 72.5 70.4 84.8 99.5 24.2 92.7 48.6 14.3 12.9 4.1 11.3 14.1 10.4 8.6 11.0 10.9 16.4 7.9 9.9 10.6 1.1 10.3 8.7 12.5 9.8 9.5 16.1 15.2 15.9 22.8 15.8 15.4 15.4 15.2 15.6 16.6 17.6 16.2 20.0 35.3 16.4 13.7 31.8 27.9 33.7 41.9 14.2 53.0 43.8 37.6 36.1 32.9 21.5 29.5 41.7 38.5 25.6 48.4 66.5 47.8 11.7 24.8 42.1 22.2 40.1 28.2 13.5 42.9 43.2 25.4 19.4 31.6 33.0 26.4 20.3 62.2 34.9 52.2 13.9 45.5 26.4 21.7 11.1 13.7 36.7 17.2 21.4 1.9 22.9 23.5 44.3 11.1 10.9 42.1 29.0 29.3 25.8 31.8 45.9 75.1 12.4 63.6 32.9 25.0 33.7 38.7 33.9 18.7 19.9 32.6 20.2 29.5 64.6 30.9 TIMM50 "TIM50, TIM50L" ENSG00000105197 "Translocase of inner mitochondrial membrane 50" Q3ZCQ8 19 39480412-39493785 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" RNA-binding "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 185.5;Late spermatids: 662.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048843, HPA056448" Enhanced Supported Nucleoplasm,Mitochondria NA NA 12000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA048843: , HPA056448: AB_2683137" "unprognostic (1.49e-1)" "unprognostic (6.97e-2)" "unprognostic (4.90e-2)" "unprognostic (2.80e-3)" "unprognostic (4.62e-2)" "unprognostic (1.45e-1)" "unprognostic (3.11e-2)" "unprognostic (7.91e-2)" "unprognostic (2.76e-1)" "unprognostic (3.11e-2)" "unprognostic (9.43e-2)" "unprognostic (2.01e-2)" "unprognostic (4.14e-3)" "unprognostic (3.04e-2)" "unprognostic (9.87e-2)" "unprognostic (3.82e-2)" "unprognostic (4.04e-2)" 37.3 37.2 31.2 30.4 33.7 45.4 29.7 34.3 44.2 27.7 31.5 32.2 30.4 33.2 11.2 35.8 27.9 18.5 75.7 35.0 35.0 32.9 43.9 25.7 27.7 35.0 32.8 27.4 35.3 36.2 22.7 25.2 33.0 27.4 15.4 8.9 32.0 17.5 127.0 26.6 29.6 23.0 30.6 26.2 31.8 80.5 32.9 21.6 31.7 76.6 18.2 30.9 26.1 33.1 147.2 365.3 59.6 155.1 43.8 33.4 116.8 115.8 54.2 119.6 97.4 262.6 96.6 156.5 126.0 67.9 71.9 81.6 100.9 114.8 56.4 148.7 170.8 140.3 94.5 197.3 81.5 282.8 106.6 51.9 73.2 97.2 78.7 33.9 76.4 184.5 237.8 91.3 77.2 202.9 178.4 110.5 113.7 159.2 123.3 190.8 112.5 119.3 88.1 195.5 166.3 99.4 133.6 190.0 251.8 35.7 89.1 168.0 86.4 154.7 165.6 140.1 262.7 96.1 181.1 232.8 117.9 146.7 179.2 42.5 53.7 13.4 36.3 58.5 34.9 41.8 34.1 40.0 60.5 46.4 41.4 35.7 5.9 45.2 58.1 47.0 47.8 62.1 31.2 33.7 34.3 44.2 35.0 35.0 35.0 32.8 33.0 30.6 32.9 33.1 20.0 22.4 26.0 4.6 19.3 26.0 43.6 57.4 18.8 10.4 23.8 28.7 47.6 24.3 37.6 25.8 12.5 83.8 14.7 27.4 66.5 56.3 185.5 19.8 24.2 28.6 23.4 29.6 8.7 51.8 84.4 30.9 25.0 21.5 39.3 29.5 19.2 31.3 67.1 28.6 9.3 27.5 48.8 18.8 27.7 662.8 23.3 22.3 30.2 3.7 22.1 17.4 21.6 6.6 4.9 50.9 22.2 21.1 34.6 68.0 35.7 66.0 22.1 11.4 6.6 27.2 55.7 111.5 46.5 32.3 26.7 94.5 19.9 34.1 48.1 47.6 TIMM8B "DDP2, FLJ21744, MGC102866, MGC117373, TIM8B" ENSG00000150779 "Translocase of inner mitochondrial membrane 8 homolog B" Q9Y5J9 11 112084800-112086798 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 577.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041173 Approved NA NA 11000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA041173: AB_10796340" "unprognostic (1.36e-1)" "unprognostic (8.82e-2)" "unprognostic (1.19e-2)" "unprognostic (1.56e-3)" "unprognostic (6.45e-2)" "unprognostic (2.79e-2)" "unprognostic (4.38e-2)" "unprognostic (5.54e-2)" "unprognostic (1.19e-2)" "unprognostic (2.40e-3)" "unprognostic (8.17e-2)" "unprognostic (4.81e-2)" "unprognostic (3.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.48e-1)" "unprognostic (3.29e-2)" "unprognostic (2.44e-2)" 35.2 55.8 35.0 23.3 36.1 34.9 30.9 37.5 49.0 27.3 36.4 31.2 19.0 22.0 25.2 65.7 19.6 9.0 137.9 35.8 36.3 38.0 51.2 21.2 21.2 36.3 35.6 18.2 21.9 24.1 22.1 17.5 35.6 25.1 23.7 15.6 28.3 17.7 106.5 34.6 23.3 20.1 36.3 27.6 27.8 31.9 36.4 29.6 21.4 97.9 22.5 27.2 32.3 36.5 43.4 56.0 105.5 89.6 45.0 27.7 50.6 43.8 29.3 55.4 54.6 198.2 53.4 19.3 96.0 53.5 46.9 57.9 82.6 61.5 29.0 55.0 116.0 86.7 77.4 125.6 70.1 98.8 45.3 53.5 28.3 59.4 20.6 20.6 84.9 84.4 74.5 86.2 52.5 114.8 75.9 113.9 52.3 126.0 97.4 65.5 49.5 121.6 107.5 118.6 85.1 61.9 71.6 100.9 33.5 47.5 123.5 75.1 62.5 58.6 77.8 48.6 54.1 30.7 73.5 137.7 21.0 97.6 55.9 100.8 146.8 157.0 54.5 156.2 52.6 91.1 55.8 53.0 157.2 85.8 64.7 54.4 80.3 93.2 133.4 213.2 91.1 113.6 35.0 36.1 37.5 49.0 35.8 36.3 36.3 35.6 35.6 36.3 36.4 36.5 83.5 54.5 41.1 6.8 66.3 82.7 69.3 247.1 66.6 44.6 136.2 167.3 577.5 178.7 142.1 101.2 31.3 222.2 78.9 257.3 360.0 229.6 96.1 103.4 141.4 94.0 142.7 118.9 7.7 227.3 184.5 100.0 95.3 124.8 60.9 90.5 110.3 444.8 297.2 33.7 8.8 166.9 185.1 138.9 76.3 181.0 98.8 115.3 168.9 2.8 185.5 125.6 116.4 4.5 12.0 220.0 210.3 88.8 106.0 107.4 195.8 515.8 96.2 69.0 72.3 63.4 132.8 193.9 158.9 224.2 148.6 129.7 54.8 185.9 208.6 94.0 TIMMDC1 "C3orf1, FLJ22597" ENSG00000113845 "Translocase of inner mitochondrial membrane domain containing 1" Q9NPL8 3 119498547-119525090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053214, HPA055846" Uncertain Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA053214: AB_2682081, HPA055846: AB_2682941" "unprognostic (3.95e-2)" "unprognostic (8.85e-2)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (9.60e-2)" "unprognostic (6.25e-2)" "unprognostic (3.39e-1)" "unprognostic (4.67e-3)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (8.89e-2)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-1)" 10.5 12.0 13.4 10.7 14.3 6.3 13.1 14.2 15.4 15.0 13.2 11.3 8.9 9.3 17.9 15.9 12.8 14.4 44.0 12.7 13.9 17.8 14.2 11.0 17.7 14.3 13.6 10.9 11.1 23.1 7.1 17.1 13.9 13.0 13.7 4.2 14.6 19.7 27.3 15.8 7.7 12.1 14.0 9.9 8.5 10.6 14.1 11.4 19.1 49.2 14.8 14.2 7.0 14.6 26.9 24.5 12.4 10.4 45.5 30.6 27.0 7.7 25.3 21.7 24.7 16.7 16.0 19.5 13.7 27.1 15.1 12.2 30.8 24.8 35.0 16.4 10.9 14.4 10.7 18.8 23.9 11.3 9.1 28.0 37.4 18.4 22.4 13.9 31.5 18.5 19.8 18.1 40.3 33.2 12.0 23.7 16.2 22.4 30.1 10.0 8.4 25.4 32.0 13.1 15.8 29.4 7.8 11.8 28.0 16.2 19.5 30.4 16.1 12.2 9.3 11.3 13.8 12.1 11.8 28.3 20.7 28.5 19.6 11.1 17.6 21.3 10.8 17.6 12.5 16.2 10.4 12.0 17.4 17.6 12.2 10.9 4.3 13.1 20.9 15.1 20.7 22.1 13.4 14.3 14.2 15.4 12.7 13.9 14.3 13.6 13.9 14.0 14.1 14.6 61.2 25.6 39.3 18.6 24.0 37.5 50.4 110.2 31.3 25.0 44.8 55.0 165.3 41.5 63.7 40.5 14.6 157.5 28.9 44.0 150.6 73.2 12.2 39.9 41.1 56.0 28.8 43.1 17.4 62.7 112.7 48.2 29.0 31.1 41.2 34.1 31.8 52.4 86.3 21.9 23.9 43.5 87.5 32.7 40.4 10.0 47.2 39.4 44.4 15.0 65.7 73.6 18.6 22.6 35.6 52.7 40.9 54.5 30.2 43.5 50.5 146.5 63.0 35.4 72.3 43.9 52.5 111.1 58.2 45.9 42.1 177.5 29.7 48.0 45.7 46.7 TLN2 "ILWEQ, KIAA0320" ENSG00000171914 "Talin 2" Q9Y4G6 15 62390526-62844631 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 38.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.7;Inhibitory neurons: 127.2;Microglial cells: 139.6;Oligodendrocyte precursor cells: 108.6;Oligodendrocytes: 93.6;Skeletal myocytes: 135.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 59.3;hTERT-HME1: 48.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017194, HPA051828, HPA054787" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 46000000 "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites, Cytosol" "CAB017194: , HPA051828: AB_2732570, HPA054787: AB_2732587" "prognostic favorable (6.53e-4)" "unprognostic (2.61e-1)" "unprognostic (9.47e-2)" "unprognostic (8.95e-2)" "unprognostic (3.74e-1)" "unprognostic (1.43e-1)" "unprognostic (8.24e-2)" "unprognostic (9.94e-2)" "unprognostic (1.68e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (1.91e-1)" "prognostic favorable (1.81e-6)" "prognostic favorable (7.74e-4)" "unprognostic (1.34e-1)" "unprognostic (5.79e-2)" "unprognostic (2.30e-1)" 19.0 4.1 14.2 2.2 15.6 3.8 10.4 3.2 16.9 8.0 20.2 9.3 4.7 3.7 2.1 2.1 4.3 1.9 12.1 18.3 8.2 38.4 4.8 2.4 0.5 7.6 8.2 4.6 4.7 2.4 5.5 1.2 6.2 2.3 7.3 7.7 7.8 2.1 26.1 3.6 5.1 2.9 11.2 1.3 5.5 5.4 7.0 3.1 13.0 12.2 0.5 4.1 4.2 13.8 1.8 5.6 8.0 9.4 59.3 5.6 9.0 13.7 10.8 12.4 12.2 15.1 1.9 4.8 6.2 24.0 20.5 2.4 10.3 2.2 10.8 15.2 1.0 0.6 22.8 10.1 2.0 1.6 0.4 10.3 5.6 16.6 48.9 7.1 0.5 5.7 0.6 0.2 21.0 7.5 0.7 0.6 14.2 26.3 4.1 5.8 20.3 5.8 6.5 11.6 1.9 9.3 10.6 1.1 3.5 17.1 2.9 3.6 3.9 22.2 30.0 36.3 35.6 0.3 0.9 3.1 10.1 3.4 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 15.6 3.2 16.9 18.3 8.2 7.6 8.2 6.2 11.2 7.0 13.8 11.5 0.0 3.2 50.6 1.1 2.4 1.8 0.7 1.2 18.6 16.5 10.2 41.1 5.7 0.9 27.6 37.5 1.2 0.7 39.0 11.7 3.5 4.3 10.9 14.3 9.0 2.4 37.7 153.7 3.9 29.7 21.5 40.8 17.4 0.0 9.3 3.3 12.6 4.9 48.8 127.2 20.0 6.1 6.2 3.1 5.2 11.8 5.5 0.0 139.6 0.8 11.1 1.0 108.6 93.6 3.7 21.0 15.8 0.7 1.5 14.6 35.1 0.1 48.3 0.0 135.6 12.3 6.7 24.5 3.1 1.6 1.4 1.3 25.8 37.7 1.7 TMCC1 KIAA0779 ENSG00000172765 "Transmembrane and coiled-coil domain family 1" O94876 3 129647792-129893606 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Alveolar cells type 1: 54.5;Astrocytes: 119.1;Excitatory neurons: 206.7;Inhibitory neurons: 201.5;Microglial cells: 127.4;Oligodendrocyte precursor cells: 181.0;Oligodendrocytes: 209.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 9.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053894 Uncertain NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA053894: AB_2682295" "unprognostic (4.26e-2)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (2.60e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (7.75e-3)" "unprognostic (1.13e-1)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.50e-2)" "prognostic unfavorable (1.77e-6)" "unprognostic (6.82e-3)" "unprognostic (2.90e-1)" "unprognostic (1.20e-1)" "unprognostic (2.32e-1)" 7.5 6.8 12.9 4.8 13.1 3.2 7.3 23.5 14.8 9.8 1.1 6.7 4.1 7.8 6.7 7.6 6.9 8.6 8.2 10.8 12.1 6.7 34.5 6.7 5.0 10.1 13.1 8.0 4.8 7.8 6.5 9.8 9.9 7.5 5.1 15.2 5.5 6.2 30.1 7.7 4.4 6.8 10.0 6.8 4.0 13.5 16.9 8.3 6.8 21.1 5.5 7.8 6.9 14.5 10.6 11.3 8.8 7.2 12.9 9.1 8.9 4.1 5.4 3.6 3.7 7.3 5.7 6.5 11.4 7.9 4.2 9.6 5.0 8.2 2.6 8.6 1.6 4.3 3.4 26.7 4.4 3.2 2.6 5.3 15.1 2.8 6.7 7.7 11.0 3.9 2.2 4.7 8.2 11.6 5.7 1.9 6.7 7.7 3.6 5.2 7.4 5.5 8.4 12.9 8.2 5.7 14.0 4.8 4.1 8.5 9.2 3.5 9.6 5.7 9.2 5.3 8.5 6.9 5.1 4.8 4.2 3.8 3.0 0.6 0.9 2.1 1.1 0.9 1.2 0.7 0.9 0.9 0.5 1.1 1.1 1.4 9.6 0.8 2.0 1.4 1.9 0.8 12.9 13.1 23.5 14.8 10.8 12.1 10.1 13.1 9.9 10.0 16.9 14.5 14.1 54.5 7.4 119.1 9.4 6.6 12.6 9.9 12.5 37.1 17.4 12.1 23.0 7.2 16.0 22.0 31.3 10.6 8.3 9.0 7.9 15.8 9.6 30.5 14.6 13.2 12.6 4.6 206.7 8.1 20.7 10.9 10.2 38.3 3.8 12.0 9.7 36.8 9.9 35.3 201.5 12.2 10.2 18.6 6.6 10.5 13.1 13.5 1.8 127.4 6.8 27.0 12.3 181.0 209.2 24.9 22.8 8.6 14.5 20.4 4.7 13.1 19.6 29.5 6.6 18.1 12.2 33.5 19.4 15.8 7.0 23.9 8.9 9.6 8.3 25.2 TMEM120A "NET29, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 289.1;Late spermatids: 1002.1;Proximal enterocytes: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.78e-2)" "unprognostic (3.35e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.26e-1)" "unprognostic (2.75e-3)" "unprognostic (6.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.15e-2)" 54.4 95.0 33.9 11.0 32.7 13.9 44.4 36.9 40.6 33.1 33.2 33.7 50.6 22.6 21.6 31.8 32.0 16.6 111.9 32.3 34.4 38.9 84.7 25.0 10.1 57.6 36.1 56.1 43.2 17.4 20.0 15.6 61.5 26.5 14.8 6.1 24.7 23.3 79.3 18.5 63.4 11.0 31.2 28.2 44.3 77.1 34.7 8.0 19.4 94.4 12.0 32.9 27.3 31.8 10.3 15.3 7.7 61.7 52.1 35.1 16.9 10.0 27.8 13.7 17.2 26.8 14.3 4.8 7.6 30.4 39.1 11.8 7.6 10.3 4.7 9.0 8.5 5.2 10.6 38.2 50.6 2.1 32.6 37.5 9.2 10.1 12.2 14.3 22.4 8.7 9.8 7.9 24.5 18.5 3.3 32.6 3.5 23.7 16.3 3.5 7.8 23.6 28.2 9.3 3.8 18.0 11.4 32.5 16.7 19.1 22.7 15.4 12.8 38.1 12.0 22.1 8.6 8.5 7.0 2.2 20.7 5.3 8.9 106.6 58.0 109.5 26.4 53.7 20.0 15.8 21.7 20.5 27.2 17.9 15.1 14.8 223.0 31.2 55.2 10.7 50.9 46.5 33.9 32.7 36.9 40.6 32.3 34.4 57.6 36.1 61.5 31.2 34.7 31.8 22.4 22.4 12.3 12.7 14.1 0.0 18.1 0.0 18.8 5.6 36.2 22.2 112.7 51.5 8.6 27.6 6.2 20.9 17.6 133.9 25.4 50.3 289.1 9.8 29.3 21.4 8.4 11.4 4.1 38.9 16.2 36.0 31.1 18.1 24.6 172.6 29.3 115.6 36.1 11.8 7.2 40.5 0.0 34.2 0.0 1002.1 40.4 36.0 0.0 3.7 23.7 12.8 18.6 4.0 7.3 40.0 108.9 30.9 24.6 17.4 414.8 118.0 4.4 7.0 39.5 46.0 31.2 113.4 15.4 33.1 0.0 10.9 20.0 31.0 43.6 28.1 TMEM126A "DKFZp586C1924, OPA7" ENSG00000171202 "Transmembrane protein 126A" Q9H061 11 85647967-85656547 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046648 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA046648: AB_2679737" "unprognostic (3.79e-2)" "unprognostic (4.75e-3)" "unprognostic (2.08e-3)" "unprognostic (1.08e-3)" "unprognostic (2.08e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (8.60e-5)" "unprognostic (8.25e-2)" "unprognostic (6.00e-3)" "unprognostic (2.66e-2)" "unprognostic (1.02e-2)" "unprognostic (6.93e-2)" "unprognostic (1.25e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-1)" "unprognostic (6.94e-2)" "unprognostic (2.17e-1)" 31.9 28.0 40.3 23.1 41.5 43.8 33.5 41.4 52.3 21.8 39.5 28.0 32.6 20.0 31.2 27.2 19.8 19.9 82.1 41.4 42.3 33.1 49.0 20.5 27.3 40.7 40.6 21.0 33.9 26.3 22.2 22.8 41.5 23.5 29.3 23.9 31.3 19.5 81.6 19.4 26.0 27.6 41.1 21.0 32.8 38.5 41.4 24.2 26.6 98.7 27.8 30.5 20.1 42.4 46.7 53.2 50.9 33.0 67.2 66.7 38.0 55.9 60.1 82.3 77.6 65.9 67.5 25.4 61.3 69.2 32.0 48.9 53.8 59.5 70.7 72.5 31.0 72.5 56.9 73.7 82.4 89.0 54.8 58.0 65.8 73.1 78.0 43.5 71.6 72.2 51.1 39.0 86.2 57.5 48.6 112.3 48.1 175.1 68.4 48.3 49.5 79.2 54.5 57.0 34.3 34.7 49.4 72.9 44.7 44.5 88.1 64.4 42.8 70.4 52.7 134.6 65.3 27.5 54.4 70.4 37.0 63.6 85.2 6.6 23.9 11.6 21.2 28.1 26.0 29.8 26.4 23.8 32.9 27.3 24.4 24.1 1.9 15.1 23.4 24.7 26.4 18.7 40.3 41.5 41.4 52.3 41.4 42.3 40.7 40.6 41.5 41.1 41.4 42.4 40.5 28.9 24.3 12.7 39.6 31.7 55.3 87.9 29.6 14.8 45.8 62.1 110.8 28.6 57.5 38.6 6.2 67.8 38.5 23.6 146.8 51.0 147.8 26.8 32.8 36.7 21.7 46.1 8.6 93.2 73.3 40.8 23.4 24.2 37.4 33.6 26.7 68.5 94.6 8.4 9.0 46.6 40.7 54.4 43.3 80.6 29.5 48.4 33.8 5.6 66.3 35.1 38.1 8.5 11.8 64.5 34.8 26.7 45.4 73.4 61.8 109.4 39.7 21.9 19.7 40.0 40.9 119.0 57.9 49.4 42.1 52.9 42.1 42.2 57.1 71.2 TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA043744: AB_10794773" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.67e-2)" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (7.22e-2)" "unprognostic (3.85e-1)" "unprognostic (1.39e-2)" "unprognostic (4.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "unprognostic (4.43e-3)" 12.6 24.3 22.5 8.6 23.2 4.7 14.8 21.2 29.9 15.6 19.9 14.0 8.3 9.6 11.0 55.5 10.2 6.5 46.8 21.6 22.2 25.2 33.9 11.2 11.9 22.8 22.6 8.6 42.9 7.9 8.7 5.3 22.4 25.7 4.5 2.8 20.6 7.3 57.4 57.5 14.5 4.4 22.7 16.2 22.4 26.5 22.9 6.6 13.5 26.0 8.8 15.9 25.4 22.5 12.3 4.6 6.5 14.0 4.3 7.3 7.2 2.5 4.6 2.9 1.2 5.8 14.3 11.7 27.2 6.2 9.2 10.0 2.9 10.7 1.8 11.3 4.9 2.2 4.5 5.9 6.6 2.3 3.2 7.3 13.4 2.3 7.7 12.7 3.0 7.9 3.0 6.6 6.3 29.0 13.3 8.6 11.0 20.4 16.3 6.5 3.8 38.5 11.3 12.5 6.0 13.3 9.1 14.2 28.6 4.4 34.5 2.3 5.8 10.4 9.0 12.5 3.3 27.8 19.4 8.2 15.6 3.0 8.5 58.2 54.3 98.5 71.4 132.7 78.8 203.7 84.2 80.6 66.6 195.7 85.6 80.6 25.7 90.2 176.0 87.3 123.9 73.3 22.5 23.2 21.2 29.9 21.6 22.2 22.8 22.6 22.4 22.7 22.9 22.5 43.3 16.0 41.5 11.8 83.0 90.0 87.7 177.7 99.0 29.3 139.9 173.4 53.4 60.1 93.5 68.0 10.4 69.5 46.5 64.7 133.1 95.0 50.2 53.0 35.3 36.6 71.4 22.3 9.4 126.0 147.9 31.3 120.3 73.4 23.4 52.5 29.3 69.6 84.0 11.8 8.2 100.3 97.6 43.6 49.3 46.2 20.8 49.0 110.3 2.8 61.2 39.5 63.8 9.5 14.1 189.9 81.7 24.8 47.2 142.6 150.8 148.9 75.0 29.5 6.6 24.4 45.9 105.8 80.1 185.1 180.1 72.8 53.3 37.6 73.5 152.2 TMEM178B DKFZp547G036 ENSG00000261115 "Transmembrane protein 178B" H3BS89 7 141074064-141480380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 11.3;parathyroid gland: 11.9;tongue: 12.2" "Group enriched" "Detected in many" 5 "Astrocytes: 175.0;Excitatory neurons: 584.8;Inhibitory neurons: 566.2;Oligodendrocyte precursor cells: 306.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 6.0;HDLM-2: 5.7;NTERA-2: 5.1;RPTEC TERT1: 8.2;SCLC-21H: 6.4;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048771 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoli "HPA048771: AB_2680517" "unprognostic (7.33e-3)" "unprognostic (2.02e-2)" "unprognostic (2.83e-2)" "unprognostic (7.79e-4)" "unprognostic (1.94e-1)" "unprognostic (1.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.69e-2)" "unprognostic (6.94e-2)" "unprognostic (2.21e-2)" "unprognostic (7.17e-4)" "unprognostic (1.05e-1)" "prognostic favorable (4.10e-4)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (5.35e-3)" "unprognostic (8.98e-2)" 0.3 1.4 3.7 0.6 5.4 0.0 0.5 0.2 7.4 0.3 0.0 0.8 0.0 0.8 0.4 0.7 0.3 0.3 11.3 7.0 5.0 1.3 0.0 0.3 1.4 1.5 5.9 0.1 0.9 11.9 4.2 0.0 5.6 2.3 0.3 5.5 1.2 0.5 4.6 0.2 0.4 1.0 0.6 0.7 0.3 0.5 5.2 1.4 8.5 12.2 3.1 0.5 0.2 1.9 0.0 0.1 0.0 0.0 0.5 0.2 1.5 0.1 2.3 0.7 0.8 0.0 0.0 1.9 2.0 0.1 0.5 0.0 6.0 0.0 1.9 5.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 5.1 0.0 0.0 0.4 0.9 2.6 8.2 2.4 6.4 3.9 0.1 0.2 0.9 1.2 0.8 0.0 0.0 0.1 0.9 2.7 0.0 0.0 0.0 0.0 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.4 0.2 7.4 7.0 5.0 1.5 5.9 5.6 0.6 5.2 1.9 1.3 0.0 0.0 175.0 0.0 0.5 0.7 0.9 0.6 25.5 1.4 0.5 48.7 0.0 1.3 1.8 2.1 0.0 0.0 0.0 1.9 0.1 1.3 0.2 0.1 1.2 0.0 0.0 584.8 0.4 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.1 30.3 566.2 0.0 2.0 0.0 0.0 1.6 0.0 0.1 1.8 24.4 0.0 4.2 0.0 306.1 81.3 0.8 0.0 0.7 0.0 2.2 0.0 3.4 0.2 1.8 0.0 3.9 0.8 1.4 0.7 2.9 0.1 0.3 0.3 0.2 0.1 2.0 TMEM186 "C16orf51, DKFZP564K2062" ENSG00000184857 "Transmembrane protein 186" Q96B77 16 8780384-8797642 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.8;Late spermatids: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018226, HPA063559" Uncertain Approved "Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Cell Junctions" "HPA018226: AB_1845579, HPA063559: AB_2685041" "unprognostic (3.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.11e-2)" "unprognostic (2.98e-2)" "unprognostic (4.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.06e-2)" "unprognostic (9.35e-2)" "unprognostic (2.45e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.93e-8)" "unprognostic (1.06e-1)" "unprognostic (3.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.89e-2)" 7.0 11.2 8.6 6.2 9.0 2.2 10.0 8.8 10.5 6.5 9.2 10.8 9.6 7.5 12.5 9.6 9.3 4.6 13.2 8.5 8.9 12.3 16.3 5.8 8.6 8.6 8.7 8.5 8.9 12.4 9.5 7.2 8.8 7.5 11.2 5.0 8.3 7.2 18.5 8.3 9.7 7.5 8.6 9.9 9.5 7.8 8.9 7.9 7.6 21.3 10.7 7.5 6.5 9.2 10.4 16.1 11.8 15.1 19.8 10.5 11.2 11.8 12.1 15.2 12.5 15.9 17.1 31.9 9.8 8.7 10.4 19.8 21.2 16.8 17.3 18.7 20.4 13.4 22.3 34.1 22.0 15.1 10.3 12.7 27.8 16.7 24.4 12.5 14.0 25.9 23.3 17.1 9.0 28.3 11.7 14.7 15.0 22.0 13.9 24.4 15.5 35.3 16.3 8.8 18.1 17.3 16.2 22.7 14.3 12.0 27.1 12.0 8.9 10.8 15.1 27.0 9.9 15.6 17.6 15.5 16.8 27.1 8.8 9.9 8.7 6.8 7.5 8.6 10.0 13.1 8.1 8.8 9.1 11.5 13.7 10.9 4.1 9.1 13.3 7.0 11.7 7.4 8.6 9.0 8.8 10.5 8.5 8.9 8.6 8.7 8.8 8.6 8.9 9.2 3.4 6.4 6.7 2.6 6.7 8.2 7.1 16.1 5.7 6.9 7.3 6.6 2.7 10.0 13.1 11.0 0.0 23.4 4.4 7.8 21.5 15.1 44.8 4.8 6.0 5.6 13.8 8.2 1.9 11.2 13.3 5.7 6.1 5.0 7.0 9.6 6.1 12.8 13.2 13.5 1.5 9.4 12.2 4.9 4.7 106.9 9.3 2.5 7.2 1.0 9.9 10.8 11.3 1.5 1.9 9.9 6.7 6.4 5.1 9.8 14.8 21.9 9.3 5.6 13.1 6.6 5.3 21.3 11.9 9.5 9.5 15.1 5.0 11.0 16.0 5.8 TMEM203 "HBEBP1, MGC14327" ENSG00000187713 "Transmembrane protein 203" Q969S6 9 137204082-137205648 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.31e-1)" "unprognostic (2.65e-2)" "unprognostic (4.53e-2)" "unprognostic (8.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.54e-2)" "unprognostic (2.72e-2)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (7.16e-2)" "prognostic favorable (4.78e-6)" "unprognostic (2.94e-1)" "prognostic favorable (1.50e-5)" "unprognostic (3.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.04e-2)" "unprognostic (1.19e-1)" 25.7 32.6 32.8 17.2 33.6 10.9 25.5 33.8 36.8 28.1 33.1 30.2 22.2 29.9 26.4 31.4 24.2 16.4 45.9 32.9 33.4 33.2 49.2 20.5 27.0 33.6 33.6 27.7 26.2 30.7 25.6 15.9 33.4 27.1 18.2 16.4 26.8 21.8 49.7 43.6 28.5 16.9 32.8 30.4 30.1 19.1 34.9 20.3 25.1 45.9 22.7 27.8 27.6 33.0 38.0 39.3 36.5 60.7 53.1 41.1 43.6 48.4 46.6 55.1 41.1 32.6 33.3 39.0 45.7 42.2 53.0 72.6 45.3 48.1 32.1 71.0 43.5 27.0 45.5 37.4 44.3 63.1 26.8 39.6 75.4 36.0 47.4 36.8 35.8 50.5 64.2 44.4 43.2 65.2 50.5 54.6 60.8 72.4 63.2 54.2 51.1 78.2 46.5 27.2 48.3 47.3 38.6 48.8 39.2 25.0 68.8 50.6 32.0 56.3 30.1 63.6 55.1 23.8 80.0 49.5 43.5 46.3 47.3 4.7 3.8 4.1 5.2 4.3 6.4 8.3 5.8 6.5 4.6 4.5 8.7 6.0 1.9 7.5 3.9 4.8 4.0 2.6 32.8 33.6 33.8 36.8 32.9 33.4 33.6 33.6 33.4 32.8 34.9 33.0 23.2 9.6 6.8 4.6 21.4 17.6 22.7 7.0 23.9 33.6 29.6 33.8 13.5 40.0 7.9 31.3 4.2 30.5 23.7 15.9 52.8 49.4 3.5 15.3 24.2 20.7 16.3 29.8 5.7 42.0 26.3 22.3 14.8 13.3 5.7 31.7 21.4 41.1 29.3 32.0 6.2 13.4 10.2 27.1 13.2 9.4 22.1 20.8 24.9 5.6 54.2 58.8 24.7 2.5 6.1 41.7 10.8 20.7 13.3 37.2 18.5 59.2 4.9 25.7 13.1 19.5 32.5 18.6 15.9 28.5 27.3 19.4 24.4 36.2 18.6 17.9 TMEM242 "BM033, C6orf35" ENSG00000215712 "Transmembrane protein 242" Q9NWH2 6 157289025-157323601 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025764 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025764: AB_1845742" "unprognostic (5.42e-3)" "unprognostic (6.02e-2)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (6.24e-2)" "unprognostic (2.21e-3)" "unprognostic (2.27e-1)" "unprognostic (2.09e-1)" "unprognostic (1.85e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (7.14e-2)" "unprognostic (1.18e-3)" "unprognostic (1.28e-1)" "unprognostic (6.50e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" 6.7 9.2 9.2 5.0 9.9 11.0 6.4 9.6 10.6 7.5 8.4 7.3 5.9 7.6 8.0 6.0 5.8 5.0 14.1 10.0 9.1 8.2 10.2 5.4 5.4 8.8 8.4 6.5 5.5 10.7 6.2 6.1 9.0 6.5 6.2 9.5 6.8 5.4 12.1 6.1 5.7 7.9 8.3 5.2 6.5 4.7 9.4 6.0 7.4 11.9 5.8 7.2 6.9 9.3 5.1 4.0 8.3 8.8 15.4 10.0 6.2 9.7 9.1 9.7 10.7 5.3 4.9 7.7 12.5 10.6 13.3 9.0 8.7 8.7 9.9 11.1 14.3 10.9 9.1 10.8 16.0 11.3 8.3 10.2 9.3 6.9 14.1 13.4 11.8 10.3 17.1 10.1 8.7 5.2 6.6 14.9 5.6 3.2 7.8 3.8 5.4 11.1 13.9 4.5 10.9 5.7 8.7 5.8 11.8 7.6 5.9 11.9 9.9 6.7 7.6 14.5 13.0 9.7 10.5 7.3 13.7 13.0 11.2 15.0 19.5 12.4 13.9 16.8 13.4 18.5 14.0 13.9 18.6 19.5 12.1 13.8 3.0 17.1 11.6 29.8 16.7 12.1 9.2 9.9 9.6 10.6 10.0 9.1 8.8 8.4 9.0 8.3 9.4 9.3 28.8 12.8 10.0 7.5 21.6 27.5 18.8 62.2 25.6 25.1 20.3 25.4 51.8 20.0 27.1 22.0 4.2 51.2 28.0 19.6 33.2 49.1 11.7 25.8 32.8 28.0 9.6 40.0 23.0 39.1 53.2 27.5 13.3 28.6 15.8 16.9 25.4 28.5 36.5 38.7 28.3 21.8 32.6 17.3 26.7 6.8 21.1 17.7 42.7 14.0 21.7 26.9 27.8 15.1 22.0 39.6 26.9 26.7 23.7 17.9 32.0 38.2 29.7 30.5 59.2 22.8 36.0 34.7 37.1 24.4 24.3 41.6 24.8 24.6 24.6 16.8 TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 163.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Actin filaments" "HPA029249: AB_2672965, HPA029250: AB_2672966, HPA029251: AB_2672967" "unprognostic (8.83e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-3)" "unprognostic (3.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.97e-3)" "unprognostic (1.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (8.60e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-2)" "unprognostic (6.12e-3)" "unprognostic (3.15e-1)" 12.4 19.6 18.1 9.5 18.9 17.9 12.6 18.9 24.7 17.8 15.1 24.6 17.1 11.4 12.1 34.6 10.7 12.8 26.5 25.1 21.0 17.1 39.2 38.3 5.8 19.9 17.5 12.1 12.6 20.2 15.6 13.6 20.4 17.4 19.4 31.6 20.9 8.6 51.6 41.4 18.5 9.9 15.7 9.8 25.4 31.0 19.8 8.6 16.2 21.2 8.6 18.8 23.2 18.3 41.7 23.1 21.1 34.6 32.3 18.6 34.6 17.0 22.8 18.7 17.7 16.1 15.7 7.2 25.5 25.3 30.1 37.8 25.6 62.6 12.3 20.6 19.5 20.8 17.2 49.1 22.2 4.6 19.2 24.8 55.5 26.2 16.7 37.8 18.9 15.3 67.7 11.2 22.0 42.7 4.6 10.3 11.4 163.7 11.2 5.8 14.0 13.2 52.2 44.5 24.3 18.8 15.2 35.5 35.8 26.0 40.1 11.6 21.8 23.8 27.0 17.9 20.7 14.0 11.1 8.8 35.9 6.6 30.7 0.2 0.4 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.2 0.2 0.4 0.2 18.1 18.9 18.9 24.7 25.1 21.0 19.9 17.5 20.4 15.7 19.8 18.3 7.2 16.0 19.7 17.6 3.3 13.6 14.9 41.3 21.1 18.4 11.2 9.3 3.8 10.0 25.1 11.0 16.7 14.1 4.2 75.1 1.9 17.0 72.9 10.6 8.9 6.9 18.6 28.4 26.3 15.2 16.6 11.0 45.9 25.1 0.0 11.0 11.7 43.4 26.4 16.8 28.4 32.4 30.5 11.7 11.4 87.6 11.8 9.1 7.2 15.0 8.5 9.4 5.2 21.6 12.1 32.5 45.7 9.1 6.4 21.9 32.7 10.8 15.7 27.6 6.6 10.4 12.0 2.1 14.7 19.4 18.3 20.0 5.5 7.1 24.3 29.4 TMEM81 "HC3107, KVLA2788, MGC75217, UNQ2788" ENSG00000174529 "Transmembrane protein 81" Q6P7N7 1 205083129-205084460 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Early spermatids: 15.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052515 Approved "Intermediate filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Intermediate filaments" "HPA052515: AB_2681858" "unprognostic (9.19e-3)" "unprognostic (3.53e-1)" "unprognostic (1.91e-3)" "unprognostic (6.48e-2)" "unprognostic (2.44e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (3.25e-6)" "unprognostic (3.66e-2)" "unprognostic (2.68e-2)" "unprognostic (6.18e-2)" "unprognostic (5.86e-2)" "unprognostic (2.48e-2)" "prognostic unfavorable (6.65e-9)" "unprognostic (8.91e-2)" "unprognostic (6.24e-2)" "unprognostic (2.42e-1)" "prognostic favorable (2.67e-4)" 2.3 3.7 8.8 1.1 9.1 1.5 1.8 11.5 12.4 4.0 8.1 2.7 0.9 2.4 2.0 2.8 2.7 0.8 4.1 9.1 8.8 4.4 6.0 2.9 1.7 8.7 8.7 4.0 2.5 1.5 3.9 1.3 8.7 3.7 1.1 4.3 2.1 1.3 6.6 3.7 2.6 1.1 8.5 5.4 2.6 5.8 9.4 3.2 2.8 2.4 1.7 2.7 3.3 9.6 1.8 2.8 4.6 6.0 6.6 2.6 2.3 3.4 2.0 1.7 1.0 5.0 1.2 3.4 2.4 1.9 2.5 1.6 7.5 2.8 3.0 3.0 2.9 2.9 3.8 2.5 4.5 1.5 1.5 2.6 5.1 2.7 1.3 4.5 3.4 4.0 6.5 1.4 2.2 3.6 3.4 6.3 3.5 2.3 4.0 2.3 5.3 3.6 4.0 1.8 2.9 4.5 2.1 2.5 5.6 7.1 1.9 6.2 1.6 3.2 1.6 4.1 3.7 3.2 4.2 2.7 4.5 2.2 5.5 1.7 0.4 0.0 1.8 0.6 0.0 0.6 0.8 0.4 0.6 0.5 0.8 1.4 1.0 0.0 0.6 0.6 1.1 0.4 8.8 9.1 11.5 12.4 9.1 8.8 8.7 8.7 8.7 8.5 9.4 9.6 0.5 0.0 0.0 2.0 0.7 2.3 0.5 0.6 0.0 0.8 1.6 1.4 2.0 1.5 0.4 3.7 0.0 0.2 1.6 0.8 0.0 0.7 15.6 1.1 0.6 0.9 0.0 0.0 2.0 0.6 0.5 0.6 0.0 1.3 0.0 2.3 0.4 1.0 0.6 1.7 1.5 0.5 2.0 0.3 2.1 3.1 0.0 0.9 1.8 1.0 0.4 1.4 3.1 1.0 1.3 0.8 0.1 0.4 1.3 1.2 0.4 1.3 0.5 1.1 0.0 1.0 0.6 0.9 1.1 0.5 2.6 0.1 0.9 0.4 0.6 1.0 TMEM94 KIAA0195 ENSG00000177728 "Transmembrane protein 94" Q12767 17 75441159-75500452 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 43.0;Granulosa cells: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008423, HPA050660" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA008423: AB_1852283, HPA050660: AB_2681207" "unprognostic (4.05e-2)" "unprognostic (3.43e-1)" "unprognostic (5.78e-2)" "unprognostic (4.32e-2)" "unprognostic (1.01e-1)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" "unprognostic (7.27e-2)" "prognostic favorable (2.26e-4)" "unprognostic (9.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.44e-2)" "unprognostic (4.96e-2)" 21.3 55.9 50.3 13.9 46.4 18.4 21.7 27.7 54.9 21.9 30.5 25.1 18.8 24.4 5.4 21.1 30.7 15.8 27.8 40.7 31.5 29.7 20.2 25.6 14.1 40.1 36.8 27.7 23.7 20.3 30.1 14.2 30.5 19.9 13.6 27.7 21.1 13.2 63.4 22.9 28.2 10.7 34.8 29.7 25.0 27.1 47.1 18.0 27.4 25.8 8.6 20.5 15.3 35.8 15.3 40.7 33.6 52.6 16.1 18.8 45.6 9.2 20.0 15.4 15.4 13.7 22.6 20.6 30.3 15.9 23.6 19.9 15.8 25.6 8.8 19.4 23.1 22.0 18.4 22.9 21.2 23.7 45.2 30.9 14.5 15.0 13.4 13.9 28.1 18.3 22.6 24.4 20.7 19.1 53.3 18.8 14.4 19.3 16.2 36.2 37.2 19.2 16.0 40.7 28.1 30.5 10.2 47.4 28.7 25.3 29.8 29.3 16.0 16.5 19.0 16.5 13.8 53.2 17.2 12.2 17.2 23.8 20.8 0.1 2.6 3.0 3.5 1.6 2.6 1.0 1.6 2.5 2.5 2.5 1.3 2.2 0.7 2.4 1.4 3.3 2.1 2.9 50.3 46.4 27.7 54.9 40.7 31.5 40.1 36.8 30.5 34.8 47.1 35.8 12.8 12.8 11.1 0.0 5.8 0.0 3.3 0.0 6.2 43.0 10.9 9.1 0.0 12.8 6.2 9.2 31.3 16.1 8.8 18.0 0.0 8.1 4.7 10.1 6.8 8.2 7.3 10.7 0.0 9.5 11.0 4.4 28.1 8.6 6.3 41.5 13.9 8.9 15.4 20.2 0.0 10.5 0.0 12.4 0.0 1.9 6.8 8.9 0.0 0.0 5.6 15.2 4.1 0.0 0.0 6.0 9.1 9.1 8.1 3.3 19.6 3.4 2.9 33.6 6.6 7.5 6.0 14.9 8.8 9.7 0.0 20.1 6.9 19.0 9.3 3.1 TMTC1 "ARG99, FLJ31400, FLJ41625, OLF" ENSG00000133687 "Transmembrane O-mannosyltransferase targeting cadherins 1" Q8IUR5 12 29500840-29784759 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Astrocytes: 64.6;Excitatory neurons: 186.0;Inhibitory neurons: 200.5;Skeletal myocytes: 60.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 83.0;HSkMC: 56.9;hTERT-HME1: 103.8;LHCN-M2: 58.8;RH-30: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016720 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA016720: AB_1858155" "unprognostic (1.67e-1)" "unprognostic (6.35e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.63e-3)" "unprognostic (4.53e-2)" "unprognostic (3.88e-2)" "unprognostic (8.36e-2)" "unprognostic (1.77e-1)" "unprognostic (8.90e-3)" "unprognostic (3.08e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.49e-4)" "unprognostic (5.89e-3)" "unprognostic (6.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.51e-3)" 36.7 14.1 14.5 5.2 21.0 0.2 16.8 6.7 13.5 11.9 13.3 11.9 3.1 9.0 3.0 6.8 14.3 7.1 16.5 20.0 25.0 14.7 2.4 8.7 2.7 11.4 24.0 9.3 2.6 28.0 10.7 2.8 15.8 6.9 5.9 2.6 4.5 8.8 18.5 4.0 6.4 13.2 7.9 42.4 8.3 2.4 25.1 6.9 4.7 31.2 2.1 12.1 8.2 6.3 0.0 0.0 15.3 0.0 47.7 31.6 0.1 14.7 33.1 4.3 3.4 0.0 0.2 0.1 7.4 10.0 17.6 0.0 0.5 0.2 0.2 0.3 4.6 0.0 41.5 0.7 83.0 2.1 0.0 56.9 5.6 40.3 103.8 12.2 2.2 0.0 0.0 2.2 58.8 0.0 0.0 0.0 11.1 0.2 20.8 0.0 122.4 2.1 0.0 0.3 1.2 1.2 1.7 0.0 4.1 5.4 0.0 0.8 6.2 3.7 2.4 2.3 12.5 19.6 0.0 0.0 27.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 14.5 21.0 6.7 13.5 20.0 25.0 11.4 24.0 15.8 7.9 25.1 6.3 105.0 3.2 0.6 64.6 0.9 3.3 1.0 6.1 11.4 12.1 1.3 10.4 32.3 0.0 2.4 3.7 0.0 0.1 0.0 0.0 0.0 0.1 29.6 7.7 16.2 57.9 0.0 0.0 186.0 0.0 0.0 17.5 2.0 7.0 0.0 4.3 54.7 5.4 0.5 0.0 200.5 0.2 0.0 17.7 4.2 7.5 8.1 4.9 10.6 30.9 0.5 0.5 0.0 9.5 5.7 0.0 0.0 18.4 0.3 4.0 0.1 0.7 6.0 1.3 46.0 60.3 24.9 2.4 1.7 1.3 2.0 1.9 1.0 21.9 0.0 0.4 TOM1L2 ENSG00000175662 "Target of myb1 like 2 membrane trafficking protein" Q6ZVM7 17 17843511-17972422 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 180.5;Cone photoreceptor cells: 158.4;Oligodendrocytes: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022541, HPA023304" Enhanced Approved "Golgi apparatus,Intermediate filaments" NA NA 73000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Intermediate filaments" "Golgi apparatus" "HPA022541: AB_1858182, HPA023304: AB_1858183" "unprognostic (2.32e-1)" "unprognostic (7.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.25e-2)" "prognostic favorable (1.24e-4)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "prognostic unfavorable (2.58e-4)" "prognostic favorable (1.92e-4)" "unprognostic (3.19e-2)" "prognostic favorable (6.21e-9)" "unprognostic (7.11e-2)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (4.51e-2)" 20.7 30.5 64.0 9.5 62.7 6.1 20.3 52.7 70.0 31.9 21.3 44.2 14.0 33.2 11.0 64.4 26.6 13.0 141.0 66.0 56.4 31.3 13.9 23.2 7.7 91.5 80.3 32.9 19.7 40.3 42.2 9.0 95.3 37.3 13.8 50.2 21.3 28.7 67.1 59.7 20.9 23.3 49.7 16.6 34.9 39.4 74.6 8.8 48.5 55.4 12.9 31.4 35.1 72.7 27.1 29.0 8.2 6.2 19.1 19.3 14.2 43.3 20.1 22.9 19.3 28.2 17.6 5.0 52.9 40.8 13.3 104.3 6.8 24.1 14.0 7.2 12.7 8.0 28.0 6.0 12.2 2.0 5.2 22.9 16.6 20.5 15.2 19.6 23.3 7.3 3.0 6.9 30.3 27.1 3.6 4.6 1.5 34.4 19.5 4.7 20.7 12.0 32.4 48.1 8.7 8.4 19.5 25.2 15.3 55.9 13.4 3.6 31.8 21.9 6.5 46.0 16.8 6.1 5.1 2.3 26.4 2.7 55.2 10.0 3.3 4.8 2.8 1.0 2.0 1.6 2.6 2.4 1.6 2.2 4.3 3.2 12.8 1.4 3.3 1.9 1.3 1.7 64.0 62.7 52.7 70.0 66.0 56.4 91.5 80.3 95.3 49.7 74.6 72.7 10.1 32.1 17.0 180.5 9.5 10.8 14.6 13.9 7.4 74.5 20.9 14.1 73.7 15.7 16.6 11.0 158.4 8.5 10.2 43.3 5.9 12.2 30.8 14.1 9.4 12.4 20.4 4.8 63.2 8.7 17.4 12.7 13.3 15.7 2.5 28.1 16.4 13.4 9.2 95.9 74.2 19.2 18.3 8.5 7.6 64.2 26.4 6.4 12.4 35.6 11.8 28.1 10.3 66.9 123.2 16.1 41.0 25.6 8.4 39.1 22.4 11.1 22.9 78.3 19.7 18.0 13.0 16.7 12.1 37.2 17.2 32.2 10.0 30.8 15.4 64.5 TOMM40 "C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40" ENSG00000130204 "Translocase of outer mitochondrial membrane 40" O96008 19 44890569-44903689 "Predicted intracellular proteins, Transporters" "Ion transport, Protein transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036231, HPA036232" Supported Enhanced Mitochondria,Cytosol NA NA 45000 "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA036231: AB_2675010, HPA036232: AB_2675011" "unprognostic (2.14e-1)" "unprognostic (9.58e-3)" "unprognostic (1.66e-1)" "unprognostic (6.75e-3)" "unprognostic (2.37e-1)" "unprognostic (2.17e-2)" "unprognostic (1.13e-3)" "unprognostic (1.13e-2)" "unprognostic (7.84e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (5.86e-3)" "unprognostic (5.30e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.87e-1)" 34.6 59.7 31.3 25.1 30.1 32.9 29.0 33.6 37.2 25.2 28.0 34.7 28.4 25.0 14.1 51.8 25.3 10.8 46.1 30.7 33.5 33.5 50.8 28.4 23.6 32.6 33.5 24.9 26.6 31.4 25.3 20.0 33.6 24.7 23.0 18.0 24.1 17.4 64.0 34.4 26.1 16.4 30.2 26.4 29.3 22.0 35.0 25.2 22.3 34.4 22.6 29.9 29.5 32.2 147.6 244.6 87.6 121.3 32.2 28.4 110.3 103.3 57.1 192.1 136.6 268.8 99.5 215.3 107.7 68.8 108.7 155.2 228.9 149.1 87.0 84.0 206.1 145.3 93.5 214.7 68.0 187.6 125.1 45.2 83.4 149.3 94.1 36.0 67.3 102.4 232.6 73.3 76.4 184.2 205.4 137.1 153.6 209.6 149.1 206.1 99.2 125.3 89.6 201.8 135.2 86.4 109.9 229.4 75.2 48.4 77.1 188.2 55.9 132.0 133.6 93.1 273.7 78.3 176.0 212.9 98.2 197.0 142.1 0.7 3.6 3.7 2.8 4.6 3.2 5.8 2.8 4.1 4.6 2.4 4.9 5.4 0.7 3.2 4.3 4.6 3.5 1.4 31.3 30.1 33.6 37.2 30.7 33.5 32.6 33.5 33.6 30.2 35.0 32.2 26.2 16.0 7.3 8.8 34.9 87.4 73.7 17.1 35.9 68.2 32.7 30.9 15.7 25.8 14.3 31.3 29.2 104.5 28.9 78.8 39.2 48.1 11.3 22.7 41.0 31.0 29.3 52.4 11.3 38.6 169.9 38.6 40.2 29.5 19.1 57.8 12.5 24.2 100.1 70.7 16.9 59.4 28.5 21.0 44.9 7.2 26.8 35.0 39.2 4.7 31.9 46.6 27.8 5.5 12.8 53.6 32.4 24.5 47.9 139.0 34.5 39.5 4.9 60.2 19.7 49.1 47.8 46.2 64.5 60.5 89.4 72.9 26.7 105.9 132.1 75.5 TOMM40L "FLJ12770, TOMM40B" ENSG00000158882 "Translocase of outer mitochondrial membrane 40 like" Q969M1 1 161225939-161230746 "Predicted intracellular proteins" "Ion transport, Protein transport, Transport" Porin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 51.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051304 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 41: Macrophages - Immune response" "HPA051304: AB_2681432" "unprognostic (1.18e-2)" "unprognostic (1.58e-2)" "unprognostic (7.65e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.58e-1)" "unprognostic (2.71e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.46e-2)" "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (1.93e-2)" "unprognostic (2.89e-2)" "prognostic favorable (7.80e-4)" "unprognostic (2.29e-1)" "unprognostic (8.71e-2)" "unprognostic (4.61e-2)" "unprognostic (1.14e-1)" 8.5 7.1 11.4 7.2 12.2 14.9 6.7 10.4 17.0 5.3 7.1 11.8 13.9 7.5 2.7 10.1 5.3 4.0 24.3 11.7 9.6 9.9 17.5 7.7 6.7 11.1 11.0 3.6 3.8 15.0 5.8 6.0 11.1 6.4 10.7 11.1 5.8 8.8 23.2 7.2 11.9 8.5 10.5 7.8 8.0 2.2 12.8 7.2 5.7 51.4 7.5 8.6 6.1 11.7 7.6 7.2 11.8 12.9 19.2 10.1 9.1 11.2 13.7 21.6 18.6 41.7 9.8 22.5 13.4 14.9 8.0 9.9 22.6 22.3 12.4 18.9 15.5 21.2 10.5 21.0 8.5 40.8 34.0 11.0 14.0 24.0 12.9 11.0 24.8 23.4 30.0 18.7 15.3 12.3 16.5 6.0 12.9 17.2 20.4 18.7 8.6 21.3 16.2 16.2 28.2 11.8 10.7 30.1 9.9 12.6 23.0 30.9 19.1 11.2 7.7 9.7 16.5 16.5 15.0 16.1 11.6 24.6 11.8 2.5 1.6 1.4 1.0 1.9 1.4 0.8 0.7 1.3 3.0 0.5 0.7 1.7 0.7 1.9 1.5 3.4 1.6 1.5 11.4 12.2 10.4 17.0 11.7 9.6 11.1 11.0 11.1 10.5 12.8 11.7 4.1 0.0 3.3 2.3 3.5 0.5 1.4 1.6 3.4 6.0 2.9 2.3 4.0 1.5 1.7 1.8 6.2 2.4 2.8 8.7 7.9 4.0 4.1 0.7 2.3 4.1 7.7 3.4 5.3 7.8 3.2 3.3 3.6 1.3 3.8 2.2 1.4 7.4 9.7 5.0 5.9 2.6 4.1 5.0 2.7 1.9 2.1 14.8 0.0 1.9 5.6 2.4 4.1 2.0 1.6 4.6 4.1 0.7 4.6 1.1 11.4 5.1 1.2 9.7 0.0 2.2 5.2 0.9 1.8 5.2 1.7 0.8 3.8 3.6 7.0 1.4 TOMM5 "bA613M10.3, C9orf105, Tom5" ENSG00000175768 "Translocase of outer mitochondrial membrane 5" Q8N4H5 9 37582646-37592604 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048712 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA048712: AB_2680499" "unprognostic (1.81e-2)" "unprognostic (1.96e-1)" "unprognostic (3.37e-2)" "unprognostic (3.34e-2)" "unprognostic (2.02e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (9.89e-3)" "prognostic unfavorable (5.49e-4)" "prognostic favorable (2.37e-4)" "unprognostic (7.80e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-1)" "unprognostic (3.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.37e-1)" "unprognostic (9.09e-2)" 90.0 92.6 69.9 62.8 72.2 66.4 71.9 71.1 84.8 62.2 68.9 84.2 74.0 64.9 62.0 89.1 58.7 47.2 83.9 71.3 75.9 114.5 87.5 57.0 83.0 70.7 73.5 63.7 90.3 52.4 66.3 39.2 77.0 58.9 60.2 40.2 70.1 46.0 129.4 63.3 62.2 55.9 72.9 75.5 72.7 65.2 70.7 72.0 65.2 89.6 78.8 79.8 65.2 70.7 353.2 400.4 234.3 211.2 265.7 258.9 128.9 262.5 169.4 252.1 268.6 431.4 142.2 240.3 208.4 253.7 254.4 119.0 212.0 316.2 262.6 338.5 329.0 212.1 535.7 630.0 216.1 350.6 133.7 224.9 170.4 277.4 273.5 118.7 293.5 264.1 524.9 261.5 261.1 282.3 297.2 306.9 407.7 296.2 249.0 247.9 195.2 353.3 294.0 218.7 202.4 184.7 134.9 181.6 201.5 198.2 127.0 405.4 198.8 173.3 369.7 273.9 411.8 97.5 312.3 407.8 211.4 300.9 272.0 77.3 155.2 74.5 202.0 177.4 252.1 309.9 246.7 227.8 196.8 260.6 251.9 232.8 17.8 216.5 154.3 218.4 221.2 279.7 69.9 72.2 71.1 84.8 71.3 75.9 70.7 73.5 77.0 72.9 70.7 70.7 31.7 28.9 33.4 16.0 95.5 112.3 49.9 72.8 138.3 5.0 51.2 66.5 20.8 47.1 54.3 46.0 12.5 24.5 41.6 36.5 80.3 55.6 218.3 43.3 49.1 49.8 18.1 120.5 14.2 127.2 55.6 45.9 122.9 46.2 46.2 22.1 50.0 159.2 66.6 1.7 14.9 50.8 52.9 52.7 48.6 181.2 35.1 55.0 62.2 6.5 58.3 10.5 32.0 6.6 11.0 109.2 32.6 31.2 178.3 67.7 75.3 215.0 51.7 8.8 0.0 40.5 42.2 87.4 24.2 235.4 146.3 25.2 73.3 20.8 53.6 55.9 TRAPPC6B ENSG00000182400 "Trafficking protein particle complex 6B" Q86SZ2 14 39147811-39170532 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047928 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum" "HPA047928: AB_2680214" "unprognostic (3.89e-1)" "unprognostic (4.94e-3)" "unprognostic (1.80e-1)" "unprognostic (1.44e-1)" "unprognostic (7.60e-2)" "unprognostic (1.55e-2)" "unprognostic (3.79e-2)" "unprognostic (1.04e-2)" "unprognostic (3.09e-2)" "unprognostic (2.07e-2)" "unprognostic (4.57e-1)" "unprognostic (2.18e-2)" "prognostic favorable (1.76e-4)" "unprognostic (2.98e-2)" "unprognostic (3.41e-1)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" 12.7 15.8 17.0 11.2 19.1 4.8 14.6 18.5 21.9 11.7 14.3 12.9 10.9 12.1 12.2 15.0 9.6 9.5 13.7 20.0 16.8 13.9 24.4 10.4 12.2 13.8 13.7 10.2 10.9 13.9 12.6 12.9 15.9 12.9 10.4 24.6 10.4 13.2 16.6 11.4 10.3 11.8 14.0 12.9 11.0 12.9 14.6 13.5 15.9 18.6 12.2 12.8 12.0 15.6 17.5 7.7 13.0 12.6 18.1 20.4 10.3 22.0 19.4 19.6 19.2 12.7 32.6 10.9 15.2 20.5 9.7 13.4 19.2 14.0 23.8 19.9 9.4 14.9 10.6 37.3 25.8 21.1 19.8 19.4 23.2 16.9 22.4 31.1 17.3 19.8 16.7 22.4 20.5 21.6 15.7 15.2 11.1 13.5 29.7 12.2 24.0 10.7 21.4 34.0 12.7 10.3 26.2 15.9 24.7 13.5 30.2 13.2 24.8 18.0 9.1 15.4 12.1 20.8 30.7 15.9 8.9 12.1 17.4 8.7 3.2 5.6 2.9 6.8 2.6 3.3 4.0 3.3 4.8 2.1 3.4 3.4 3.3 7.7 7.1 4.8 3.6 2.4 17.0 19.1 18.5 21.9 20.0 16.8 13.8 13.7 15.9 14.0 14.6 15.6 20.0 22.4 19.4 24.2 20.3 22.6 19.7 17.9 25.6 25.3 18.2 12.6 24.0 10.0 15.6 18.4 35.5 14.2 28.7 12.4 54.8 14.3 38.8 12.1 17.6 17.5 16.6 27.6 47.0 17.4 13.1 22.0 18.8 18.4 29.2 15.5 23.6 22.8 15.7 23.5 50.6 9.6 26.4 15.0 21.3 16.0 16.1 23.0 17.8 13.1 18.2 16.0 27.8 31.2 45.0 22.2 12.6 17.7 21.4 19.2 11.3 20.7 10.8 39.4 26.3 15.5 21.1 58.9 31.3 29.7 25.1 22.6 22.3 26.8 10.1 30.1 TRAPPC9 "IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120" ENSG00000167632 "Trafficking protein particle complex 9" Q96Q05 8 139727725-140458579 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 89.5;Excitatory neurons: 121.8;Inhibitory neurons: 136.3;Late spermatids: 119.0;Microglial cells: 105.9;Oligodendrocyte precursor cells: 93.5;Oligodendrocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026579 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA026579: AB_1854459" "unprognostic (1.82e-2)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.14e-2)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.76e-2)" "unprognostic (2.31e-1)" "prognostic favorable (5.11e-6)" "unprognostic (2.09e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.62e-1)" 8.6 13.4 10.3 6.9 11.0 11.1 8.9 10.7 12.7 10.3 12.5 11.1 8.0 11.3 5.1 12.3 12.2 5.8 15.0 10.8 10.3 13.8 11.6 9.5 8.0 13.1 14.1 10.5 11.9 27.4 20.7 7.2 13.9 11.7 6.0 14.2 11.6 8.3 33.5 11.4 10.9 7.2 10.2 11.3 12.5 9.0 11.9 11.3 12.9 17.6 6.8 11.1 10.8 13.0 9.6 16.6 7.4 20.8 15.5 9.0 4.9 6.0 9.9 3.1 5.0 6.2 11.2 11.6 14.0 11.9 4.7 12.2 10.0 9.4 3.4 16.8 6.1 18.6 9.8 6.2 11.2 4.7 14.5 8.9 9.3 2.5 7.9 11.1 12.9 13.1 6.7 10.1 5.1 27.0 29.2 6.2 2.3 31.3 14.0 12.2 2.7 19.4 11.6 11.6 19.1 10.6 9.8 4.7 10.6 7.6 15.3 6.8 7.7 4.6 7.9 10.8 4.9 14.1 10.9 7.8 9.6 10.1 7.4 15.4 3.5 2.9 4.2 3.3 4.6 2.7 2.9 3.3 3.5 4.4 2.8 3.6 5.0 4.9 3.4 4.2 2.1 3.5 10.3 11.0 10.7 12.7 10.8 10.3 13.1 14.1 13.9 10.2 11.9 13.0 5.1 3.2 8.3 89.5 9.6 2.3 4.7 3.1 5.7 14.2 5.5 4.1 13.9 5.7 5.3 11.0 20.9 10.9 5.4 15.2 9.8 6.5 47.9 8.4 3.7 6.5 30.5 3.4 121.8 6.2 4.4 5.3 29.6 10.2 8.8 7.9 4.6 9.2 7.5 28.6 136.3 14.4 10.2 10.5 3.7 119.0 5.9 10.3 10.6 105.9 5.3 13.6 11.3 93.5 170.6 5.1 6.6 7.9 11.0 3.7 13.4 19.9 15.7 13.7 6.6 9.0 5.3 3.6 6.6 8.7 3.0 14.6 10.5 8.6 12.0 5.4 TRIM55 "MURF-2, RNF29" ENSG00000147573 "Tripartite motif containing 55" Q9BYV6 8 66126896-66175485 "Predicted intracellular proteins, Predicted membrane proteins" "Muscle protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 61.8;liver: 37.9;skeletal muscle: 29.6;tongue: 33.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 108.9;Endometrial ciliated cells: 64.7;Hepatocytes: 30.4;Skeletal myocytes: 31.0;Spermatocytes: 23.8" "Group enriched" "Detected in some" 10 "liver cancer: 12.3;renal cancer: 5.8" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "LHCN-M2: 426.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038793, HPA053691" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" Cytosol "HPA038793: AB_10673289, HPA053691: AB_2682231" "unprognostic (5.44e-3)" "unprognostic (1.25e-2)" "unprognostic (5.93e-3)" "unprognostic (4.07e-2)" "unprognostic (6.83e-3)" "unprognostic (3.77e-3)" "unprognostic (8.31e-2)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (5.18e-2)" "unprognostic (2.10e-2)" "unprognostic (9.51e-2)" "unprognostic (1.16e-2)" "unprognostic (1.77e-3)" 1.4 0.0 0.1 0.1 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.1 0.1 3.5 0.8 5.3 0.1 61.8 0.0 0.0 4.8 37.9 0.2 0.0 0.1 0.6 0.0 0.2 0.2 0.4 0.0 0.3 0.7 0.1 0.0 1.3 0.2 29.6 0.4 0.1 0.1 0.0 0.1 0.0 7.3 0.0 0.2 0.3 33.7 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 7.2 0.1 0.3 0.1 0.0 0.4 0.5 0.6 0.0 60.5 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.2 426.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.7 1.5 27.6 0.0 2.4 0.0 0.0 0.1 0.0 91.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.1 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.6 0.0 0.1 2.8 0.0 0.0 0.1 0.0 108.9 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 11.8 64.7 0.2 1.2 0.0 0.0 0.2 0.0 0.1 3.8 0.0 3.5 0.0 0.0 0.7 30.4 0.1 0.0 1.5 0.0 0.0 1.3 0.0 6.4 0.9 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.4 0.2 0.0 0.0 7.4 15.4 0.0 6.6 31.0 2.9 23.8 1.2 0.0 0.0 3.8 0.3 0.0 0.0 0.3 TRMT61B FLJ20628 ENSG00000171103 "TRNA methyltransferase 61B" Q9BVS5 2 28849821-28870309 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026747, HPA026751" Enhanced Uncertain Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA026747: AB_1848782, HPA026751: AB_1848784" "unprognostic (1.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.63e-3)" "unprognostic (2.05e-2)" "unprognostic (3.32e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.36e-2)" "unprognostic (2.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.52e-2)" "unprognostic (2.52e-2)" "prognostic favorable (9.61e-5)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (5.38e-2)" "unprognostic (2.34e-1)" 8.8 13.1 9.8 8.5 9.9 9.2 13.1 12.1 17.0 9.4 12.0 8.4 14.1 10.1 14.0 8.6 8.1 7.2 15.2 9.8 9.9 14.4 12.6 6.6 11.0 9.7 9.8 9.4 7.0 15.1 9.0 8.9 10.0 10.6 9.3 9.4 8.7 7.9 13.8 8.7 14.1 10.3 9.8 8.7 9.2 7.4 9.7 10.2 9.1 16.6 9.1 10.7 7.5 10.6 28.5 16.7 16.7 29.6 22.3 19.0 20.1 16.5 20.3 20.6 19.2 19.3 15.0 29.9 14.8 14.5 24.7 21.7 23.5 20.1 21.3 22.6 15.8 9.1 13.6 25.7 25.2 19.4 10.0 19.5 22.0 16.4 22.2 15.2 20.0 19.1 18.9 11.2 17.2 11.3 17.3 29.6 31.0 33.6 26.7 12.7 26.9 26.1 18.2 18.2 28.1 29.8 17.8 27.8 28.5 13.9 14.2 6.7 15.8 13.7 23.1 13.6 21.0 13.7 24.2 46.6 18.1 28.9 18.8 0.0 8.0 3.5 11.2 8.5 13.8 14.5 12.4 12.0 7.8 14.1 13.7 9.9 1.1 17.7 7.1 8.3 14.7 7.4 9.8 9.9 12.1 17.0 9.8 9.9 9.7 9.8 10.0 9.8 9.7 10.6 10.2 16.0 8.7 18.3 17.7 18.1 11.0 23.7 17.1 10.8 9.9 10.2 2.8 11.5 14.7 9.2 6.2 22.1 11.8 4.5 15.6 14.5 9.3 9.4 11.8 8.5 4.8 10.9 38.0 10.2 13.8 10.8 21.4 7.7 9.5 15.8 7.5 11.5 9.2 6.7 34.8 9.8 20.3 7.3 8.2 3.6 8.7 7.0 7.2 7.5 11.0 10.3 8.2 36.2 32.2 10.3 8.5 10.5 13.5 7.6 23.6 30.3 15.0 21.6 6.6 12.2 10.6 24.1 9.7 15.3 15.8 8.8 12.4 15.9 12.1 7.3 TRMU "FLJ10140, MTO2, MTU1, TRMT" ENSG00000100416 "TRNA mitochondrial 2-thiouridylase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA000824: AB_2732393, HPA035273: AB_10602901, HPA043300: AB_2678415" "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavorable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favorable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavorable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" 4.2 7.5 7.7 2.3 7.8 2.9 4.0 8.3 9.6 4.3 8.3 4.5 4.7 3.6 7.5 5.6 3.4 2.6 11.2 7.6 8.5 9.1 8.8 3.5 5.0 8.5 8.6 4.0 10.2 8.0 5.3 4.1 8.5 4.4 4.1 2.8 5.5 4.7 6.9 4.8 4.0 3.9 7.9 4.2 4.3 2.3 8.5 3.0 4.6 8.4 4.3 4.2 4.1 7.8 17.8 16.0 6.6 15.1 12.2 8.6 16.6 18.1 12.6 24.9 19.2 22.7 4.5 11.5 12.5 16.2 10.9 15.3 28.5 16.0 21.1 7.5 38.4 13.6 25.0 27.1 10.4 26.5 9.0 8.2 17.6 25.8 8.1 10.3 16.2 5.8 19.3 2.7 15.3 19.1 10.4 21.5 25.5 10.6 27.5 12.2 14.4 21.2 12.5 12.1 15.9 19.0 16.0 18.5 31.7 8.2 10.7 10.9 11.9 11.1 19.8 15.8 20.7 6.5 7.8 12.6 15.7 19.1 22.8 0.0 6.2 3.8 9.4 9.0 8.3 5.4 8.2 8.9 7.1 5.5 7.3 6.9 1.3 8.0 9.8 5.8 11.0 5.9 7.7 7.8 8.3 9.6 7.6 8.5 8.5 8.6 8.5 7.9 8.5 7.8 12.7 9.6 6.1 22.9 13.2 6.2 10.8 16.8 7.4 26.4 10.6 11.8 14.7 10.0 10.7 11.0 16.7 24.9 16.1 14.1 27.4 20.1 1.6 6.3 10.2 14.5 12.5 14.3 19.4 19.6 21.0 11.9 21.9 6.6 9.5 26.8 13.9 16.8 15.9 13.5 18.0 12.3 10.2 9.9 4.0 3.3 15.2 8.8 8.8 5.6 14.9 11.9 20.6 10.1 14.6 19.5 9.9 17.0 13.8 14.2 15.3 27.9 10.2 26.4 6.6 7.6 14.4 18.5 12.9 9.6 9.7 15.3 13.1 21.0 19.3 9.9 TRUB2 CLONE24922 ENSG00000167112 "TruB pseudouridine synthase family member 2" O95900 9 128305159-128322447 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021211 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA021211: AB_1858375" "unprognostic (2.40e-1)" "unprognostic (2.02e-2)" "unprognostic (1.31e-1)" "unprognostic (3.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (4.52e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (3.04e-2)" "unprognostic (4.81e-3)" "prognostic favorable (5.57e-10)" "unprognostic (8.74e-3)" "unprognostic (8.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" 3.7 8.5 8.7 3.6 9.0 4.2 4.7 8.9 9.3 3.3 8.7 4.5 5.0 3.3 2.9 6.3 4.1 2.7 8.7 8.5 8.1 6.5 12.9 2.4 4.5 9.3 9.3 3.8 5.2 7.2 6.8 2.7 9.8 3.6 4.2 3.6 4.8 3.4 7.2 5.4 4.3 3.2 7.7 3.6 4.6 3.1 9.5 3.5 4.7 9.8 4.3 4.0 3.5 9.9 6.6 14.9 6.7 9.2 10.7 7.9 7.1 7.1 8.5 11.6 9.5 11.1 8.3 14.7 6.0 9.7 11.0 17.5 15.4 12.4 7.8 7.1 10.2 6.9 12.8 10.4 8.2 12.7 8.9 10.0 13.7 11.4 10.7 7.2 12.0 12.8 26.2 6.4 9.3 19.7 17.1 14.7 9.2 22.2 19.0 13.3 10.9 21.0 10.7 5.9 14.4 10.6 13.2 14.6 9.5 5.2 19.1 8.7 8.1 9.4 7.5 11.2 8.6 7.5 16.4 11.9 9.9 9.9 10.5 3.6 3.6 1.1 5.0 3.8 5.7 6.3 4.8 5.7 5.5 5.3 5.5 5.7 1.8 6.5 2.0 3.8 6.2 3.8 8.7 9.0 8.9 9.3 8.5 8.1 9.3 9.3 9.8 7.7 9.5 9.9 10.9 25.6 10.3 1.6 17.1 9.6 13.7 43.0 15.4 21.3 14.6 15.7 49.9 24.3 27.0 35.0 16.7 51.6 10.9 19.8 64.6 39.0 12.9 15.1 20.7 16.4 19.1 16.2 5.0 35.4 45.9 15.4 27.0 15.9 8.2 22.0 17.2 50.7 31.0 3.3 5.2 26.4 34.6 9.0 4.1 16.4 20.8 12.4 12.4 3.7 16.8 15.4 18.6 3.0 10.5 27.2 19.1 18.0 17.8 14.9 34.0 78.6 16.9 16.7 0.0 17.2 16.3 15.8 19.2 22.1 10.5 28.0 13.9 46.1 35.3 11.1 TUSC2 "C3orf11, FUS1, PAP, PDAP2" ENSG00000114383 "Tumor suppressor 2, mitochondrial calcium regulator" O75896 3 50320027-50328251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030116 Approved Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Vesicles "HPA030116: AB_10602253" "unprognostic (1.58e-2)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (8.46e-2)" "unprognostic (2.73e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.53e-3)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.47e-2)" "unprognostic (1.99e-2)" "prognostic favorable (8.70e-7)" "unprognostic (9.22e-3)" "unprognostic (1.98e-1)" "unprognostic (3.15e-1)" "unprognostic (6.34e-3)" 17.7 25.4 53.4 14.9 54.1 12.4 17.0 51.0 56.2 16.3 43.9 25.2 12.8 17.7 28.2 18.9 20.6 11.5 35.4 54.8 55.5 29.2 25.9 18.4 17.1 54.6 56.2 15.8 27.4 34.8 21.5 17.3 55.6 22.1 16.6 36.0 18.4 17.8 50.9 13.8 20.3 13.7 50.5 23.7 26.9 22.6 56.1 20.4 23.1 36.4 20.5 20.5 14.2 50.8 24.7 20.2 27.5 30.1 29.8 15.4 30.1 19.3 26.5 36.3 30.7 35.6 22.0 41.8 21.0 18.3 37.4 15.5 33.9 25.7 31.7 24.8 31.2 20.6 18.6 38.7 26.1 36.7 34.8 16.8 40.7 36.5 18.1 25.5 38.0 32.8 25.4 19.6 21.1 18.8 38.7 46.5 37.6 30.4 28.9 13.3 13.4 34.4 36.9 26.4 14.7 30.3 14.4 25.4 29.9 27.2 24.2 44.3 30.3 10.8 26.6 24.8 40.2 47.6 79.7 29.4 24.2 24.1 17.4 16.7 21.2 34.6 24.0 19.6 24.3 23.0 20.8 25.2 14.2 24.6 23.5 25.2 30.2 22.4 18.1 26.3 25.2 32.3 53.4 54.1 51.0 56.2 54.8 55.5 54.6 56.2 55.6 50.5 56.1 50.8 39.8 12.8 17.0 3.9 41.7 57.5 36.8 60.7 37.0 55.5 61.0 44.2 39.6 55.8 37.9 57.0 22.9 62.9 54.4 46.5 115.4 73.9 123.1 55.6 15.8 39.2 50.4 40.4 12.9 74.1 55.5 24.9 25.0 28.4 29.9 16.4 40.4 72.7 76.6 74.0 11.4 46.1 73.2 46.1 51.1 351.8 27.1 37.7 55.2 5.6 57.6 69.0 59.8 4.0 7.8 74.0 61.0 24.8 45.8 67.8 72.0 178.6 71.5 45.5 13.1 18.0 38.5 54.1 49.2 47.4 91.2 69.6 38.7 28.9 46.1 63.7 TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 84000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008681: AB_1623682, HPA000994: AB_1080267" "unprognostic (5.11e-2)" "unprognostic (4.40e-3)" "unprognostic (4.40e-3)" "unprognostic (1.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.28e-2)" "unprognostic (4.02e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic favorable (2.04e-4)" "prognostic favorable (1.17e-6)" "unprognostic (1.49e-2)" "unprognostic (2.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" 60.3 182.3 89.8 45.5 92.4 64.7 58.0 94.6 98.2 57.4 92.4 65.3 84.0 50.0 51.7 79.8 64.1 49.4 122.3 87.9 90.7 91.5 149.5 44.7 59.2 92.9 91.3 75.8 59.2 99.1 43.4 47.3 91.9 59.3 63.6 43.0 59.5 52.5 159.4 60.5 64.3 48.3 91.2 65.7 76.1 48.8 97.0 50.9 67.7 180.1 59.9 59.0 54.0 91.7 52.8 80.4 75.4 126.8 115.2 125.0 81.3 70.8 108.1 114.8 128.7 87.9 52.1 133.3 64.2 116.8 54.5 76.1 151.7 127.4 66.1 93.6 131.8 147.7 91.7 125.4 94.6 189.6 125.8 162.3 98.9 101.9 79.3 99.5 118.2 78.4 157.7 104.1 106.1 80.3 87.5 128.2 60.0 170.3 95.3 75.3 79.5 92.6 116.4 84.8 99.9 98.3 70.2 148.1 125.3 61.3 103.6 165.9 83.7 120.5 95.0 69.8 65.9 81.4 64.2 128.6 111.0 109.5 74.1 30.2 173.5 32.3 102.5 194.3 108.9 140.4 101.2 109.0 223.4 133.8 116.4 108.6 59.3 145.4 170.1 167.1 110.9 224.3 89.8 92.4 94.6 98.2 87.9 90.7 92.9 91.3 91.9 91.2 97.0 91.7 68.9 60.9 53.0 12.1 66.4 83.5 87.7 154.0 108.1 105.6 124.3 137.7 105.4 88.6 82.5 69.9 39.6 213.2 62.8 128.5 303.3 93.0 19.6 45.7 70.6 73.7 89.5 114.0 8.3 106.2 275.8 74.0 75.4 57.2 69.1 148.0 81.0 122.7 173.4 116.1 10.3 132.4 95.6 100.5 80.7 36.8 56.5 80.7 78.2 8.4 91.9 168.9 77.2 9.0 13.5 82.5 104.3 50.8 79.5 52.7 252.2 213.7 49.0 59.4 19.7 61.1 67.1 49.1 42.4 124.5 89.8 207.1 62.4 287.0 179.6 87.1 TXNL4A "DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD" ENSG00000141759 "Thioredoxin like 4A" P83876 18 79970813-80033949 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, mRNA splicing" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 360.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041324 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane" Cytosol "HPA041324: AB_2677410" "unprognostic (7.56e-2)" "unprognostic (1.06e-3)" "unprognostic (5.94e-2)" "unprognostic (2.67e-2)" "unprognostic (6.99e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.45e-1)" "unprognostic (9.39e-2)" "unprognostic (3.31e-3)" "unprognostic (7.61e-2)" "unprognostic (4.94e-2)" "unprognostic (3.11e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" 61.1 79.1 88.1 39.9 92.5 59.6 52.1 96.0 98.7 37.2 94.9 53.5 32.8 35.7 50.3 69.4 38.1 24.1 88.6 95.0 98.4 87.7 97.1 48.2 53.4 89.4 95.8 32.6 86.0 42.2 95.5 31.6 94.1 53.9 33.2 36.5 55.0 25.3 88.5 59.3 48.0 25.6 93.1 67.8 60.5 88.0 91.6 52.4 51.1 61.3 45.6 46.1 45.5 99.3 98.5 129.3 113.0 108.1 90.3 94.7 99.8 104.3 83.5 138.7 124.9 121.2 68.0 118.8 37.8 100.3 94.1 81.4 137.1 121.5 91.2 139.7 173.7 85.6 196.1 288.7 115.4 247.6 134.1 88.6 105.5 98.7 125.6 87.9 132.4 145.0 76.2 168.0 97.8 177.1 177.0 166.3 88.6 74.3 276.9 106.2 75.7 245.4 137.7 152.7 172.1 125.0 51.6 151.8 200.5 96.9 74.6 145.0 62.9 121.3 149.5 55.7 129.4 74.0 302.3 198.6 113.4 185.7 113.9 10.6 10.3 9.0 14.7 12.7 9.9 15.8 11.8 11.6 14.5 17.6 11.7 14.0 8.2 15.6 13.1 31.3 17.3 6.1 88.1 92.5 96.0 98.7 95.0 98.4 89.4 95.8 94.1 93.1 91.6 99.3 81.0 19.2 42.6 14.0 89.2 87.2 76.9 73.6 64.3 35.7 131.9 139.7 80.3 65.8 62.3 66.2 35.5 107.8 104.8 53.6 360.0 123.4 259.3 98.5 66.0 65.2 56.3 94.1 25.3 125.2 156.9 69.8 71.4 88.1 11.4 84.1 47.2 97.4 126.0 45.4 22.5 88.4 59.0 66.4 76.9 245.5 42.0 89.5 94.3 14.0 87.2 81.5 60.8 21.1 34.8 144.5 54.9 45.1 177.9 177.2 48.6 271.8 41.9 51.3 46.0 61.2 100.8 84.6 74.2 147.6 109.8 96.7 78.7 112.6 71.1 119.4 U2AF1L4 "MGC33901, U2AF1L3, U2af26" ENSG00000161265 "U2 small nuclear RNA auxiliary factor 1 like 4" Q8WU68 19 35742464-35745445 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052083, HPA061644" Supported Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA052083: AB_2681720, HPA061644: AB_2684574" "prognostic favorable (2.44e-4)" "unprognostic (1.31e-1)" "unprognostic (2.39e-3)" "unprognostic (1.31e-2)" "unprognostic (2.35e-1)" "prognostic favorable (2.58e-5)" "unprognostic (3.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (3.67e-2)" "prognostic favorable (8.58e-5)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (1.06e-1)" "unprognostic (7.21e-2)" "unprognostic (1.92e-1)" "prognostic favorable (7.05e-4)" 2.6 3.7 8.9 1.5 9.9 1.7 2.2 8.6 12.6 3.5 7.1 5.5 1.6 3.5 0.0 2.3 3.9 0.5 11.4 9.5 9.9 4.3 2.4 2.4 0.4 9.8 9.3 4.4 2.2 5.4 5.4 1.8 9.6 3.7 0.6 4.6 1.8 3.0 9.1 1.5 2.6 2.1 8.8 2.5 3.5 8.5 9.2 2.6 2.8 6.9 0.9 4.1 2.5 9.9 4.1 13.7 2.2 3.3 0.4 1.6 3.0 3.3 3.4 8.3 8.2 5.1 3.3 1.7 6.6 7.7 7.7 1.9 6.7 5.4 5.1 10.7 1.5 2.3 3.4 5.9 10.2 2.6 5.5 2.0 2.1 3.4 2.0 3.0 1.6 5.2 4.4 4.6 5.5 8.5 8.0 2.5 3.1 8.9 2.7 2.2 3.0 0.0 1.9 0.6 4.5 4.1 5.0 3.7 1.2 4.4 3.7 4.9 2.9 5.3 2.2 1.4 5.5 5.4 7.0 3.5 4.1 5.9 6.6 0.0 2.0 1.7 2.9 4.0 2.9 8.4 5.7 5.5 2.4 6.8 8.1 7.8 2.3 0.9 2.7 9.0 10.2 3.3 8.9 9.9 8.6 12.6 9.5 9.9 9.8 9.3 9.6 8.8 9.2 9.9 12.0 19.2 25.4 7.8 40.9 10.3 14.3 34.7 10.2 26.9 19.8 18.9 4.7 8.6 16.5 9.2 14.6 14.9 35.2 20.1 27.4 11.1 13.9 6.5 8.9 11.9 12.6 7.8 6.5 12.6 9.4 13.6 12.2 7.8 36.6 10.3 10.4 18.3 19.2 20.2 7.1 13.4 48.8 18.5 36.3 15.6 15.5 18.4 30.2 1.9 27.9 12.3 30.9 4.5 7.7 9.5 22.5 12.4 38.4 12.0 23.6 26.6 12.7 29.3 13.1 15.2 16.7 36.7 16.0 9.3 8.8 29.6 39.1 12.6 10.7 12.7 UBB "FLJ25987, MGC8385" ENSG00000170315 "Ubiquitin B" P0CG47 17 16380798-16382745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013048, HPA041344, HPA049132" Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "CAB013048: AB_2533002, HPA041344: AB_2677422, HPA049132: AB_2680646" "unprognostic (1.16e-1)" "unprognostic (2.98e-1)" "unprognostic (2.55e-1)" "unprognostic (7.34e-2)" "unprognostic (3.86e-1)" "unprognostic (9.32e-2)" "unprognostic (1.29e-3)" "unprognostic (2.48e-2)" "unprognostic (5.81e-2)" "unprognostic (2.15e-3)" "unprognostic (2.88e-2)" "unprognostic (1.45e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 942.4 1676.7 1564.8 674.6 1589.2 2376.9 770.4 1662.2 2231.7 812.8 1565.4 1065.5 1179.6 788.9 1367.0 656.3 656.8 813.0 1668.3 1644.2 1719.8 1593.6 2982.1 1046.3 1002.7 1672.3 1765.4 726.2 1305.1 1677.7 1373.8 1012.3 1713.9 808.0 1097.8 566.0 1294.6 861.8 2656.6 692.3 1134.0 932.4 1670.6 1078.8 1245.6 1591.8 1597.4 1226.8 1181.5 2162.1 993.0 974.7 689.1 1980.8 1646.5 3022.4 1559.8 1912.1 1530.0 963.9 1131.3 1609.5 2166.2 2855.8 2453.4 2916.5 1270.4 1662.3 2631.3 1916.6 1678.5 1295.4 0.8 1054.2 3076.0 2126.4 2231.3 1649.8 1653.1 2183.7 1022.3 6.6 2162.4 1468.9 1010.2 2183.4 848.2 1486.0 1582.3 1562.2 1888.9 1530.9 1743.0 3858.5 2354.7 2086.6 1288.4 4642.0 1177.2 2185.1 1984.7 1484.1 2312.8 1911.4 1179.0 1757.0 2109.6 1239.7 1454.4 3025.5 1392.6 1936.0 1152.7 1417.8 867.8 1087.6 2507.7 845.7 1238.7 1366.4 1688.3 1757.9 1356.3 5348.4 1684.4 3262.9 2632.2 2121.6 2131.1 3065.4 2048.1 2372.7 1501.1 2872.4 1787.4 2146.5 981.5 3290.2 1875.7 2799.7 2592.8 7841.1 1564.8 1589.2 1662.2 2231.7 1644.2 1719.8 1672.3 1765.4 1713.9 1670.6 1597.4 1980.8 1607.0 1003.2 1168.4 46.7 786.3 979.5 1548.2 1890.9 796.2 426.2 763.6 1161.1 370.3 948.0 1262.5 551.8 120.9 1661.1 1082.7 1377.9 1829.3 1114.8 3648.2 961.6 510.0 870.9 922.4 4506.0 29.1 880.2 996.8 1202.3 1270.6 799.9 1800.7 412.4 669.3 1509.8 1168.9 233.9 37.3 1351.2 1310.2 589.0 1180.7 2126.9 592.4 826.6 1812.5 50.6 1001.9 912.0 1051.5 30.7 133.6 751.3 1879.5 775.2 700.4 974.6 1970.0 3101.7 2080.6 506.8 880.9 714.4 3554.9 3297.7 1090.7 739.1 1112.3 1815.4 1231.6 935.0 993.8 1036.2 UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 282.2;monocytes: 215.5;NK-cells: 193.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA037444 Approved Approved Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA037444: AB_10672491" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (3.80e-2)" "unprognostic (6.92e-3)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (3.43e-3)" "unprognostic (6.64e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.59e-7)" "unprognostic (2.04e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" 26.7 29.7 33.0 25.5 33.7 41.8 22.8 35.9 40.6 27.7 32.5 29.6 24.7 23.1 53.0 43.1 18.8 28.7 56.7 33.4 38.0 28.2 44.2 22.6 32.1 37.5 37.7 12.6 70.5 41.8 21.0 39.9 38.7 25.4 33.7 16.0 25.2 30.3 60.7 18.8 26.9 35.6 35.5 23.7 26.5 26.0 36.1 34.5 35.4 69.1 33.1 40.7 23.5 38.3 42.9 23.9 53.6 55.1 69.2 83.0 74.8 38.9 55.5 43.3 44.4 26.0 26.4 22.0 13.7 88.7 93.7 35.1 62.3 84.9 67.9 33.7 22.7 31.6 28.5 86.6 86.2 13.1 70.1 48.1 137.7 57.9 87.1 40.1 78.1 100.8 94.2 13.7 80.1 64.0 35.1 55.9 59.8 60.9 33.8 41.8 35.0 39.1 66.3 17.8 36.0 53.0 45.2 36.2 77.0 89.4 31.0 52.8 49.7 47.6 41.7 54.9 43.1 17.1 14.3 43.6 57.1 38.4 35.8 112.4 50.0 63.8 66.3 68.2 26.2 26.2 44.8 40.4 45.0 25.4 40.7 41.4 37.3 102.3 78.5 56.4 51.6 63.6 33.0 33.7 35.9 40.6 33.4 38.0 37.5 37.7 38.7 35.5 36.1 38.3 17.6 6.4 18.4 0.0 26.4 32.5 24.1 33.0 11.4 24.2 37.7 24.9 48.1 30.0 21.6 27.6 8.4 84.9 87.3 38.6 56.7 49.7 23.6 15.0 23.9 27.1 41.8 102.5 0.0 79.4 282.2 24.9 15.8 13.8 21.5 13.1 22.1 41.7 152.7 26.9 0.0 58.1 32.6 72.2 105.7 61.3 25.7 67.6 35.6 0.0 215.5 28.3 193.6 0.0 0.0 71.8 31.9 30.9 25.7 46.0 49.7 62.2 23.4 21.7 39.5 14.8 31.4 123.5 79.4 19.0 40.3 65.7 36.2 16.0 35.5 34.6 UBE2G2 UBC7 ENSG00000184787 "Ubiquitin conjugating enzyme E2 G2" P60604 21 44768580-44801826 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 211.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003332 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" "HPA003332: AB_1858525" "unprognostic (7.58e-2)" "unprognostic (5.41e-2)" "unprognostic (1.58e-2)" "unprognostic (4.45e-2)" "unprognostic (6.30e-2)" "unprognostic (4.67e-2)" "unprognostic (5.99e-2)" "unprognostic (3.79e-3)" "unprognostic (6.93e-3)" "unprognostic (7.02e-2)" "unprognostic (1.40e-2)" "unprognostic (6.98e-3)" "prognostic unfavorable (7.02e-5)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.55e-2)" 26.7 20.9 21.1 13.4 22.8 25.9 17.5 21.9 24.7 13.5 20.0 22.2 13.3 20.2 8.4 16.1 16.3 12.1 34.7 21.3 21.8 24.4 27.6 16.9 16.2 22.4 22.3 13.7 26.7 20.5 8.2 14.2 22.6 14.8 14.1 20.7 12.6 21.3 61.3 15.3 16.6 20.4 22.1 19.7 21.6 12.2 22.0 22.9 16.9 51.8 14.9 21.2 12.5 24.2 51.9 11.5 34.9 44.3 46.2 20.6 31.3 37.0 27.5 29.5 31.7 40.5 6.7 66.4 33.4 35.8 38.6 20.5 49.4 43.5 27.2 61.9 51.1 107.3 7.0 33.6 35.5 79.2 19.4 33.3 50.0 39.5 39.5 14.7 47.0 71.3 99.8 47.9 43.0 24.6 89.2 13.3 86.7 35.4 44.2 73.2 31.1 61.2 41.4 28.3 39.3 72.5 49.6 18.2 52.3 30.5 17.6 68.5 37.3 31.1 21.2 28.5 58.5 73.8 144.7 64.1 29.3 96.1 36.3 3.2 16.1 8.5 20.8 16.8 22.8 16.0 19.0 21.5 17.3 16.2 20.1 21.3 4.9 20.8 20.1 24.6 21.1 17.4 21.1 22.8 21.9 24.7 21.3 21.8 22.4 22.3 22.6 22.1 22.0 24.2 54.6 57.7 115.4 70.8 48.3 47.7 38.4 32.0 39.3 58.8 37.3 34.0 70.6 28.6 48.4 53.3 66.7 40.7 53.3 29.8 25.4 32.9 63.4 36.8 68.5 54.1 30.0 37.4 56.3 40.7 26.3 41.3 26.0 49.7 43.6 66.6 37.1 69.7 35.3 32.0 57.5 31.2 26.4 42.2 37.4 211.1 41.3 42.9 28.4 32.8 43.2 39.5 49.4 73.9 56.7 43.2 21.5 50.4 53.6 55.6 27.4 36.7 43.0 102.2 26.3 59.3 42.8 42.9 49.4 44.9 56.0 35.8 49.4 75.6 46.0 40.9 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952960 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 365.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Approved Mitochondria NA NA 21000 "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 46.8 64.7 43.0 29.1 44.2 42.3 34.4 46.4 49.1 44.7 58.7 42.3 23.4 44.3 37.6 49.9 44.6 44.6 98.2 42.1 45.4 42.1 44.2 38.8 31.8 48.7 43.4 41.7 84.3 49.2 29.4 52.5 45.0 36.1 26.0 42.0 39.3 41.5 69.3 31.2 24.4 49.2 41.8 28.6 34.6 36.4 45.8 37.4 45.0 60.6 39.8 40.1 33.7 47.8 82.6 43.8 58.5 56.1 126.1 107.5 86.5 72.0 97.8 45.8 51.1 22.9 92.5 34.0 87.4 76.6 123.8 62.5 46.2 81.6 59.5 40.9 22.6 11.5 63.5 28.6 98.3 23.6 36.8 146.7 106.9 61.3 99.7 106.3 89.7 36.3 27.5 104.1 71.5 29.9 31.1 26.1 80.0 60.5 49.8 24.4 27.8 77.2 95.9 106.5 20.3 59.6 68.3 164.7 43.8 166.0 17.1 27.2 89.1 51.7 24.2 72.2 76.5 83.5 65.6 58.5 102.1 28.9 49.7 2.2 1.4 3.4 2.8 1.2 3.8 2.3 2.8 2.6 1.3 4.5 3.6 3.8 4.8 0.9 1.5 2.3 4.4 1.3 43.0 44.2 46.4 49.1 42.1 45.4 48.7 43.4 45.0 41.8 45.8 47.8 69.9 41.7 51.8 87.1 43.1 145.8 187.5 65.7 59.7 65.1 83.7 49.4 102.9 44.3 69.3 71.7 60.5 116.3 56.7 38.6 41.1 66.0 93.5 225.7 91.2 81.4 59.1 100.0 97.1 70.9 67.1 65.2 43.8 365.8 14.7 53.9 45.3 73.1 41.8 43.7 116.9 35.3 54.9 40.3 69.8 44.0 44.1 52.0 48.0 89.0 26.2 87.4 51.5 113.1 108.5 118.3 33.6 78.6 60.5 227.6 27.6 49.7 95.3 35.6 13.1 65.9 69.0 46.5 22.5 78.6 153.7 200.4 49.2 79.7 26.6 274.3 UBE2M "hUbc12, UBC12" ENSG00000130725 "Ubiquitin conjugating enzyme E2 M" P61081 19 58555712-58558954 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 1197.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004993, HPA054551, HPA057800" Approved Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" Yes No 49000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB004993: AB_436983, HPA054551: AB_2682520, HPA057800: AB_2683531" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.35e-2)" "unprognostic (1.77e-1)" "unprognostic (1.17e-3)" "unprognostic (3.90e-3)" "unprognostic (4.86e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-3)" "unprognostic (1.96e-1)" "unprognostic (1.81e-1)" "unprognostic (8.63e-3)" "unprognostic (1.76e-1)" "unprognostic (5.85e-2)" "unprognostic (8.42e-3)" 46.3 66.1 133.2 39.2 138.8 82.2 42.8 116.7 199.7 48.9 104.0 72.5 41.7 48.1 36.3 61.8 51.3 30.9 111.0 141.2 129.3 63.2 45.6 46.3 43.4 123.5 124.4 46.0 47.5 84.5 69.7 45.0 127.7 48.3 32.5 49.7 48.5 46.1 174.0 56.6 41.6 39.5 111.9 49.3 55.8 81.0 124.4 51.7 44.3 104.5 43.7 58.3 45.8 139.1 161.8 272.1 119.3 124.8 61.7 71.9 112.2 166.0 117.4 97.8 82.8 162.7 109.7 161.9 135.5 93.4 198.1 105.9 130.1 138.6 69.2 207.3 1197.4 235.5 163.7 113.7 154.4 197.3 192.9 82.1 107.1 145.9 167.3 102.6 117.8 146.3 119.6 179.4 127.3 158.2 177.2 223.7 87.1 155.1 306.5 171.7 106.7 204.5 111.6 166.8 239.5 205.5 133.1 149.7 163.3 41.6 94.4 188.4 105.2 333.4 80.5 110.6 281.3 262.3 411.9 169.6 206.0 177.6 220.5 6.7 3.6 4.2 3.0 2.6 2.2 2.8 3.2 3.2 2.8 3.8 3.3 2.2 10.1 1.7 2.7 6.7 2.9 1.9 133.2 138.8 116.7 199.7 141.2 129.3 123.5 124.4 127.7 111.9 124.4 139.1 75.1 6.4 13.0 14.7 32.7 40.4 36.3 15.9 6.2 100.0 74.5 81.3 38.5 20.0 11.6 18.4 20.9 21.0 72.9 63.9 7.9 17.3 25.7 89.6 68.0 40.1 41.2 39.8 22.9 30.6 22.4 38.9 21.9 63.3 19.7 103.3 28.5 38.0 35.4 109.4 20.8 43.8 20.3 27.0 33.5 34.0 17.4 42.5 35.6 15.9 21.1 142.3 14.4 8.5 17.9 41.8 21.4 13.9 35.4 59.1 37.9 33.9 18.6 81.1 26.3 41.5 55.4 27.1 7.9 17.0 56.8 52.5 41.0 156.1 41.6 56.2 UBE2O E2-230K ENSG00000175931 "Ubiquitin conjugating enzyme E2 O" Q9C0C9 17 76389456-76453152 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.7;Inhibitory neurons: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023605 Uncertain Supported "Nucleoplasm,Nuclear bodies" No No 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nuclear bodies" Nucleoplasm "HPA023605: AB_2671257" "unprognostic (8.75e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (8.68e-2)" "unprognostic (1.17e-1)" "unprognostic (3.22e-2)" "prognostic unfavorable (6.84e-8)" "unprognostic (3.54e-1)" "unprognostic (2.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (4.34e-9)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" 9.1 9.7 12.9 10.1 14.0 21.2 9.7 8.0 24.9 12.8 1.4 10.7 9.4 11.5 7.0 12.8 11.0 6.5 20.3 15.4 11.7 8.4 10.5 8.7 13.1 21.7 9.0 15.1 17.4 10.9 18.2 9.1 21.7 11.6 5.3 10.5 12.9 8.7 28.3 16.1 10.6 7.1 4.4 13.9 11.0 16.6 11.6 12.0 16.1 13.4 8.6 10.8 12.5 14.5 25.8 29.2 29.1 35.5 17.7 11.3 25.2 11.8 12.8 18.9 18.3 25.6 12.7 36.4 8.3 14.8 29.7 25.2 34.2 20.4 13.2 10.5 42.2 36.9 20.6 42.9 14.7 22.6 22.0 11.4 16.2 18.1 15.3 16.2 25.7 19.9 31.5 31.4 9.6 21.3 44.7 26.0 27.0 15.5 38.9 43.3 37.6 40.2 8.5 22.1 43.0 38.5 17.4 43.9 23.6 26.3 25.4 16.1 15.4 21.9 20.5 18.8 19.9 25.8 9.2 30.8 24.1 18.8 14.6 0.0 0.7 1.0 1.4 0.3 0.8 0.9 0.9 0.7 0.4 1.6 0.7 1.1 0.1 0.5 0.4 1.5 0.9 0.8 12.9 14.0 8.0 24.9 15.4 11.7 21.7 9.0 21.7 4.4 11.6 14.5 7.9 3.2 7.7 24.8 19.6 8.7 6.1 7.2 13.1 45.8 9.7 9.1 23.2 5.7 7.3 7.3 41.7 6.4 15.2 6.5 0.0 6.0 1.8 8.6 13.7 8.3 23.4 33.2 54.7 9.4 7.4 8.3 17.9 10.1 7.0 18.9 7.1 8.5 8.1 45.4 63.0 9.3 2.0 5.3 11.0 1.8 9.6 11.6 5.4 19.7 10.0 7.3 18.6 27.2 24.7 7.2 5.7 7.9 22.9 9.8 5.2 3.3 5.6 23.8 6.6 12.2 10.9 19.6 23.2 12.9 12.4 5.2 14.7 13.3 8.7 6.2 UBE2V2 "DDVit-1, DDVIT1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2" ENSG00000169139 "Ubiquitin conjugating enzyme E2 V2" Q15819 8 48008415-48064708 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052535, HPA053186" Supported Nucleoplasm NA NA 800000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA052535: AB_2681863, HPA053186: AB_2682073" "unprognostic (3.50e-3)" "unprognostic (3.27e-1)" "unprognostic (1.53e-1)" "unprognostic (3.07e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (2.94e-3)" "unprognostic (1.21e-2)" "unprognostic (1.65e-3)" "unprognostic (4.97e-2)" "unprognostic (1.77e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (4.96e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-1)" "unprognostic (2.45e-1)" "unprognostic (9.62e-2)" 36.6 42.9 40.0 32.1 44.0 23.0 35.5 38.3 50.3 28.2 33.5 43.7 35.1 32.9 26.7 49.0 26.2 27.5 25.3 45.7 47.0 35.8 60.8 23.3 39.2 44.4 42.2 24.4 21.4 36.9 36.0 31.4 45.2 34.0 36.1 52.1 23.2 30.8 56.3 25.4 33.0 38.3 39.6 23.7 32.8 34.3 46.4 52.1 37.2 56.0 39.7 41.7 31.7 38.6 112.7 63.9 140.0 78.0 75.4 83.6 49.4 114.8 80.1 113.8 99.2 80.9 85.3 136.9 65.7 110.5 97.4 66.1 128.6 107.8 152.1 47.2 89.8 123.6 74.4 68.8 94.0 68.2 35.7 79.5 109.9 91.7 145.6 86.1 97.6 115.8 154.0 83.0 145.3 85.7 218.3 131.6 130.3 166.7 42.2 108.3 61.8 67.6 122.7 90.0 152.9 99.4 96.7 85.1 107.5 103.8 143.0 89.7 54.1 95.8 87.8 86.6 108.7 82.3 151.5 175.8 124.3 118.7 104.0 73.9 70.5 74.4 58.9 84.9 71.6 77.4 72.6 72.8 87.2 76.1 72.2 81.7 45.1 110.6 85.0 73.3 104.6 94.2 40.0 44.0 38.3 50.3 45.7 47.0 44.4 42.2 45.2 39.6 46.4 38.6 52.4 48.1 34.7 20.2 53.1 45.2 75.5 172.5 36.5 87.1 40.9 51.8 58.9 35.8 89.0 51.5 16.7 93.3 39.9 29.9 129.1 81.9 51.6 46.7 58.3 45.4 32.3 57.0 41.6 88.3 149.6 67.9 30.5 36.9 50.8 55.5 32.2 50.8 90.4 80.8 38.1 49.2 109.9 35.4 53.1 34.6 56.2 51.6 37.4 20.6 76.0 110.8 56.7 21.1 28.4 83.6 56.0 73.4 46.7 95.9 51.9 130.2 71.4 65.2 59.2 48.3 122.1 134.7 82.2 46.8 57.1 149.7 47.2 76.2 59.3 75.0 UBL5 ENSG00000198258 "Ubiquitin like 5" Q9BZL1 19 9827892-9830115 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 3183.1" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.53e-1)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (4.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.96e-1)" "unprognostic (7.30e-2)" "unprognostic (7.85e-2)" "unprognostic (8.51e-2)" "unprognostic (3.14e-3)" "unprognostic (2.04e-2)" "unprognostic (4.79e-2)" "unprognostic (1.05e-2)" "unprognostic (3.64e-1)" "unprognostic (1.07e-2)" "unprognostic (3.19e-2)" "unprognostic (2.23e-3)" 303.2 450.0 486.9 202.3 501.8 323.7 287.0 503.9 613.4 291.0 537.1 331.2 218.5 263.8 513.6 375.8 261.5 213.8 648.9 493.9 514.4 476.6 401.6 263.1 280.8 495.3 488.5 269.5 227.0 486.4 439.5 215.7 497.7 300.7 264.1 274.7 278.8 284.9 533.4 261.1 259.7 248.4 515.9 303.6 303.5 275.3 492.8 427.3 304.3 567.0 322.2 297.8 278.2 534.1 609.5 633.1 536.4 508.8 755.8 589.0 320.0 434.9 519.8 557.0 687.0 800.0 338.5 374.8 745.6 651.7 475.1 380.9 562.1 634.2 532.7 629.4 1032.4 1110.5 783.3 1328.0 508.8 1105.1 471.2 612.2 658.5 406.4 437.8 569.2 630.0 798.3 697.9 888.0 669.8 1016.8 758.8 3183.1 534.7 758.8 1046.3 444.4 435.8 972.4 1054.9 1138.9 474.9 616.1 380.3 358.4 568.1 612.2 397.3 1029.3 517.3 608.9 277.1 787.5 579.1 1046.1 1812.3 800.4 540.0 713.6 370.6 865.4 497.7 1271.3 424.7 488.1 410.8 445.4 468.2 464.3 466.7 352.4 395.3 430.8 818.7 395.9 529.2 780.2 618.9 756.0 486.9 501.8 503.9 613.4 493.9 514.4 495.3 488.5 497.7 515.9 492.8 534.1 387.5 256.4 330.2 8.1 329.4 397.7 342.1 779.0 236.2 177.4 479.0 535.4 763.9 446.1 491.5 662.1 62.6 549.6 422.1 970.8 1486.9 574.3 168.8 613.3 370.8 335.4 433.4 400.4 6.8 519.7 598.4 336.7 284.4 523.3 400.8 305.2 327.7 932.9 705.0 126.2 6.7 693.1 571.7 447.8 548.4 130.6 472.5 423.9 499.8 8.4 729.1 591.6 503.6 6.6 11.9 645.8 1081.0 495.0 427.5 460.5 1117.0 1610.2 642.1 230.1 355.0 284.4 417.4 622.6 596.8 420.5 519.0 585.7 395.1 235.8 555.7 495.3 UCK1 "FLJ12255, URK1" ENSG00000130717 "Uridine-cytidine kinase 1" Q9HA47 9 131523801-131531264 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050969, HPA070526" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Nucleoli "HPA050969: AB_2681294, HPA070526: " "unprognostic (2.20e-1)" "prognostic favorable (3.19e-4)" "unprognostic (1.16e-2)" "unprognostic (1.74e-3)" "unprognostic (7.29e-2)" "unprognostic (1.43e-1)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.54e-1)" "prognostic favorable (2.21e-7)" "unprognostic (5.11e-2)" "unprognostic (3.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.07e-1)" 21.5 25.3 40.3 10.2 41.2 16.4 20.4 40.5 45.2 21.2 37.0 26.0 11.8 20.2 18.7 21.2 19.9 12.2 28.1 38.1 39.2 29.3 52.7 17.2 15.1 41.6 41.4 22.2 29.8 22.6 24.2 14.3 40.0 26.9 9.3 13.5 25.6 17.3 43.9 19.1 18.0 11.2 40.7 20.9 24.9 20.4 42.1 17.5 23.4 26.8 11.5 20.9 17.2 40.9 13.9 30.0 33.9 43.8 23.6 16.7 28.9 22.0 32.1 37.0 28.0 30.1 12.4 15.0 12.9 26.4 28.9 26.3 31.9 28.0 15.8 27.7 29.8 14.0 46.3 19.2 33.6 23.2 19.9 18.8 25.8 29.9 21.6 22.4 23.0 36.3 17.9 11.2 27.6 55.2 31.9 11.8 40.4 27.0 29.6 30.1 52.5 25.1 24.1 13.0 45.7 28.9 31.8 23.9 34.3 15.4 46.6 13.5 17.1 40.9 20.7 25.7 21.7 22.7 31.3 19.4 20.3 16.0 29.1 2.1 5.5 9.0 7.3 7.2 9.8 7.4 8.5 6.4 5.2 8.0 11.3 5.6 3.6 7.0 2.6 5.9 12.0 5.6 40.3 41.2 40.5 45.2 38.1 39.2 41.6 41.4 40.0 40.7 42.1 40.9 13.6 16.0 5.0 7.8 12.4 14.3 10.3 9.9 12.5 18.0 16.2 20.1 14.0 4.3 6.2 14.7 8.4 33.8 12.0 20.4 29.4 22.7 21.9 9.0 10.2 14.3 12.1 3.0 4.7 26.2 17.5 15.7 6.6 9.2 2.5 16.2 13.2 20.5 26.4 26.9 6.1 11.6 16.2 10.0 13.4 33.3 17.7 14.0 16.0 4.7 20.4 22.0 9.2 2.0 6.0 18.6 12.3 19.9 8.0 14.3 21.1 31.6 3.1 13.1 19.7 12.4 17.2 32.8 33.4 11.8 12.5 25.7 10.0 14.9 14.8 8.5 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097597-109110992 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 64.9;Spermatogonia: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 19.8 56.7 32.4 14.7 32.4 16.0 23.1 30.1 34.8 16.6 27.7 28.0 17.1 14.5 12.7 29.7 15.6 10.4 21.1 29.2 34.9 27.5 32.2 9.6 18.0 32.2 31.4 15.7 12.4 33.2 10.9 17.8 34.1 13.6 29.3 6.8 17.7 17.6 43.0 32.7 18.8 14.5 31.6 16.1 17.7 24.3 33.5 22.8 22.2 33.5 27.0 13.5 20.1 30.8 77.1 77.5 72.8 66.6 118.6 33.8 69.5 44.4 30.1 68.6 52.3 61.7 51.6 100.3 65.1 40.2 35.9 47.6 81.4 46.0 66.4 85.6 150.9 98.1 41.1 105.5 17.7 147.6 58.2 30.7 41.6 33.0 18.3 54.6 50.4 117.8 80.9 32.5 47.0 96.2 136.8 173.6 130.0 124.2 117.7 123.9 109.8 85.9 43.4 95.6 103.3 57.4 79.6 67.8 39.5 94.2 126.2 68.2 26.0 59.1 52.7 39.3 62.5 62.6 145.0 190.5 44.8 97.7 73.8 12.9 2.7 5.0 22.4 5.3 31.6 16.0 25.5 25.6 6.8 17.2 16.4 18.4 0.0 16.5 5.5 4.9 25.5 14.4 32.4 32.4 30.1 34.8 29.2 34.9 32.2 31.4 34.1 31.6 33.5 30.8 26.6 0.0 4.8 16.0 9.2 18.0 11.0 13.2 25.0 2.6 21.7 14.1 12.4 7.2 5.0 42.3 4.2 64.9 12.5 14.7 19.6 14.4 3.4 7.6 15.0 17.7 8.4 32.4 7.0 6.2 38.1 12.6 14.3 9.9 7.6 24.8 20.3 20.8 18.3 5.0 6.2 21.4 10.2 3.8 5.4 4.2 14.0 5.5 14.2 6.5 3.8 15.8 7.2 6.6 4.0 5.0 10.3 14.7 16.7 6.8 9.3 20.2 3.2 3.5 6.6 10.2 11.5 21.9 74.6 37.8 20.9 20.4 15.3 25.7 40.4 9.7 UQCC1 "BFZB, C20orf44, CBP3, FLJ10850, UQCC" ENSG00000101019 "Ubiquinol-cytochrome c reductase complex assembly factor 1" Q9NVA1 20 35302566-35412031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 64.6;Inhibitory neurons: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034875 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA034875: AB_10603226" "unprognostic (9.66e-2)" "unprognostic (3.93e-1)" "unprognostic (3.45e-1)" "unprognostic (8.72e-3)" "unprognostic (4.01e-1)" "unprognostic (1.31e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (2.82e-2)" "unprognostic (7.66e-2)" "unprognostic (3.42e-2)" "unprognostic (7.01e-2)" "unprognostic (6.72e-3)" "unprognostic (3.23e-1)" "unprognostic (3.60e-1)" "unprognostic (5.27e-2)" "unprognostic (1.34e-2)" 19.4 30.0 22.0 13.8 24.3 4.6 16.5 21.9 27.7 20.1 20.9 26.0 18.9 18.6 22.9 18.8 20.6 12.6 55.3 22.4 23.0 28.6 27.1 15.8 17.9 24.1 23.5 19.8 15.9 37.2 23.9 14.9 26.6 19.7 25.8 29.5 18.7 18.4 106.8 16.3 19.3 18.5 19.9 19.7 23.0 17.6 22.9 21.2 22.3 105.7 21.9 20.1 18.0 22.8 20.2 28.6 33.5 32.2 34.1 38.4 4.8 38.5 43.3 70.7 48.1 97.7 39.4 66.6 68.5 26.1 60.7 53.5 60.0 70.0 52.6 19.0 24.2 89.2 41.3 80.3 22.7 54.2 25.6 37.6 72.3 37.9 48.8 51.2 24.6 53.5 39.9 23.9 50.0 26.8 58.6 29.2 25.4 42.0 61.5 31.4 50.0 37.9 67.6 26.2 46.4 28.7 32.9 148.9 34.0 28.1 23.9 34.6 23.5 46.2 28.8 25.9 34.6 30.1 37.2 26.5 79.7 31.1 36.8 28.6 10.2 14.2 14.8 14.3 18.3 12.3 13.7 14.7 16.0 15.7 16.7 14.7 0.3 22.3 10.2 14.4 14.2 12.6 22.0 24.3 21.9 27.7 22.4 23.0 24.1 23.5 26.6 19.9 22.9 22.8 7.0 0.0 7.8 51.6 7.0 6.4 9.3 18.1 6.8 20.7 7.8 5.8 44.0 10.0 11.8 16.5 8.4 22.9 5.3 13.9 60.7 18.2 15.1 10.5 8.5 10.5 12.0 5.2 64.6 13.1 15.7 9.2 7.7 6.9 8.2 17.5 6.1 14.2 11.6 18.5 68.9 9.1 18.3 6.6 3.9 8.6 10.5 5.8 14.2 33.7 13.2 16.7 10.3 44.2 50.3 19.1 6.6 12.0 5.0 8.4 10.9 19.4 14.8 22.8 6.6 9.6 11.9 24.6 18.2 6.2 5.3 17.4 6.2 19.7 13.2 9.6 UQCR10 "HSPC051, QCR9, UCCR7.2, UCRC" ENSG00000184076 "Ubiquinol-cytochrome c reductase, complex III subunit X" Q9UDW1 22 29767369-29770413 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4406.3;Distal tubular cells: 2296.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.09e-1)" "unprognostic (2.96e-3)" "unprognostic (1.56e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (2.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.75e-3)" "unprognostic (3.05e-2)" "unprognostic (9.24e-3)" "unprognostic (2.94e-1)" "unprognostic (1.12e-2)" "prognostic favorable (5.45e-5)" "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.80e-3)" 87.8 167.6 175.5 59.0 182.2 72.2 70.8 186.9 221.3 58.7 180.2 124.6 111.7 54.0 72.1 111.0 70.4 52.4 433.7 181.4 186.4 169.9 170.0 75.4 68.4 177.2 175.8 61.9 73.4 142.8 98.8 53.7 177.0 94.6 87.6 90.4 85.4 64.0 509.1 73.7 98.2 52.9 179.6 89.8 121.7 101.7 182.0 81.0 86.3 463.5 65.8 79.5 71.0 178.1 173.3 177.3 167.7 131.3 154.0 100.8 93.1 93.8 116.2 164.1 170.8 230.4 96.8 129.6 99.6 149.7 120.5 168.2 200.6 219.9 101.8 162.6 423.2 162.2 200.9 512.2 110.1 210.7 170.0 169.8 132.0 171.6 115.1 137.4 124.1 137.3 112.6 169.8 163.8 434.9 159.4 246.5 96.6 413.1 232.4 171.3 134.6 235.1 289.7 324.3 184.6 92.9 109.3 231.7 156.2 105.7 164.5 198.9 98.2 168.4 204.8 104.8 141.3 127.2 140.2 176.0 152.2 161.4 108.7 982.0 782.2 1009.7 455.0 820.3 503.6 1000.7 620.1 587.4 842.3 830.2 670.6 571.5 552.9 554.9 762.4 864.6 890.3 1160.1 175.5 182.2 186.9 221.3 181.4 186.4 177.2 175.8 177.0 179.6 182.0 178.1 138.4 246.8 290.2 42.7 231.0 181.8 205.4 1090.3 149.1 167.6 354.1 421.9 4406.3 443.2 563.5 627.1 77.2 680.2 215.8 819.5 2296.9 438.5 356.7 361.2 190.9 200.9 380.1 380.7 26.0 553.2 549.2 291.0 423.5 345.2 150.1 279.1 180.2 1306.4 737.2 114.4 33.8 791.0 783.3 390.7 254.0 652.3 234.6 337.1 311.3 15.9 424.2 455.0 310.0 16.1 32.4 499.6 771.6 206.5 293.4 335.2 1114.8 1872.1 522.9 307.1 210.4 150.2 327.7 577.2 165.7 490.0 281.7 582.0 226.2 346.5 782.7 389.6 UQCR11 "QCR10, UQCR" ENSG00000127540 "Ubiquinol-cytochrome c reductase, complex III subunit XI" O14957 19 1597169-1605473 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 297.7;skeletal muscle: 311.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1792.1;Hepatocytes: 2200.3;Proximal enterocytes: 2007.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.90e-1)" "unprognostic (6.67e-3)" "unprognostic (1.78e-1)" "prognostic favorable (1.23e-4)" "unprognostic (5.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (5.42e-3)" "unprognostic (9.10e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.86e-4)" "unprognostic (1.03e-1)" "prognostic favorable (1.65e-4)" "unprognostic (2.40e-1)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (1.06e-2)" 71.0 80.2 74.9 20.6 79.6 39.7 60.5 79.4 103.7 46.8 78.6 91.7 59.7 46.4 18.4 71.6 43.6 25.0 297.7 76.4 76.7 103.4 136.4 48.7 27.4 76.5 77.7 35.5 49.5 46.8 62.7 24.1 76.6 62.0 22.8 13.8 53.9 30.9 311.8 50.4 62.6 22.6 75.6 60.9 77.2 24.7 78.3 24.1 52.6 109.7 19.3 60.9 51.4 79.0 68.9 75.7 34.7 74.5 60.8 40.7 79.9 54.3 45.4 55.5 48.8 121.5 47.3 47.4 51.8 41.8 12.3 46.8 55.5 61.0 26.5 65.0 163.1 40.6 87.3 114.0 60.6 66.1 57.9 62.8 62.6 35.2 41.6 28.6 50.8 66.9 94.8 73.1 36.2 111.5 67.7 72.4 94.8 59.2 176.0 40.4 36.2 148.9 74.6 158.4 69.6 65.9 39.3 86.4 99.7 27.9 59.3 65.1 66.7 44.3 30.0 129.9 57.7 110.4 101.2 54.4 82.6 69.9 64.8 619.6 421.3 521.9 282.7 367.9 287.1 390.0 341.7 316.6 360.5 333.8 324.3 314.1 496.7 273.7 354.9 448.4 407.7 872.4 74.9 79.6 79.4 103.7 76.4 76.7 76.5 77.7 76.6 75.6 78.3 79.0 300.4 269.2 379.1 20.5 287.6 0.0 189.6 0.0 206.6 135.2 715.6 798.8 1731.6 529.0 159.7 634.5 39.6 481.8 380.1 834.6 1792.1 665.4 178.2 290.5 220.2 282.4 452.6 451.6 17.8 811.6 632.1 262.0 342.0 243.5 199.3 152.6 463.3 2200.3 962.9 89.2 17.6 681.7 0.0 783.5 0.0 474.8 252.8 472.2 0.0 10.3 866.6 418.8 568.5 9.5 25.1 855.3 727.0 259.5 384.1 365.5 2007.4 1742.3 267.5 164.4 223.5 192.6 291.3 159.2 145.3 520.3 0.0 512.8 304.3 188.0 717.0 290.3 UQCRC1 "D3S3191, QCR1, UQCR1" ENSG00000010256 "Ubiquinol-cytochrome c reductase core protein 1" P31930 3 48599002-48610976 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 766.7;tongue: 882.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 662.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002815, HPA003525, CAB033782" Enhanced Supported Mitochondria NA NA 250000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB033782: AB_2213631, HPA002815: AB_1080486, HPA003525: AB_1080484" "unprognostic (1.29e-1)" "unprognostic (3.15e-3)" "unprognostic (6.91e-3)" "unprognostic (1.06e-1)" "unprognostic (1.66e-1)" "unprognostic (9.91e-2)" "unprognostic (8.53e-2)" "unprognostic (1.99e-1)" "unprognostic (3.11e-2)" "unprognostic (9.14e-2)" "unprognostic (3.37e-1)" "unprognostic (7.20e-2)" "prognostic favorable (2.35e-10)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "unprognostic (1.02e-1)" "unprognostic (6.72e-2)" 66.0 58.2 93.7 46.9 97.1 62.4 55.0 117.3 110.1 50.7 127.2 156.9 156.3 35.5 50.4 78.9 66.2 33.9 387.7 96.7 115.0 131.3 149.0 42.1 42.8 111.0 101.7 36.1 87.4 192.2 30.6 56.0 114.6 51.8 129.6 52.9 105.9 77.5 766.7 78.6 125.4 62.8 99.3 41.0 103.3 52.1 111.6 72.7 48.4 882.7 58.0 63.5 40.0 101.4 118.2 169.6 136.7 145.0 147.5 117.0 225.2 129.4 206.1 196.5 178.9 272.8 107.1 193.4 94.4 143.2 274.1 123.6 171.6 280.9 91.7 138.3 173.8 214.7 186.7 317.1 186.9 164.4 152.2 150.9 293.6 183.2 274.6 167.5 172.5 173.7 110.5 107.1 152.5 192.0 156.7 241.6 157.6 229.6 324.2 103.4 138.1 273.5 235.8 178.7 84.4 107.5 182.8 218.7 211.8 92.0 163.1 178.0 112.5 107.7 153.7 179.5 272.4 124.8 121.4 136.5 192.7 233.9 319.0 251.3 643.7 325.4 204.7 665.7 193.7 260.0 203.5 206.1 593.3 227.7 177.1 175.2 158.2 194.4 608.0 235.0 258.1 988.2 93.7 97.1 117.3 110.1 96.7 115.0 111.0 101.7 114.6 99.3 111.6 101.4 31.5 57.7 50.4 17.3 59.0 117.6 164.6 339.4 103.6 41.9 59.3 46.1 662.2 140.2 139.2 121.4 29.2 334.4 28.0 550.2 365.9 163.7 155.0 64.0 41.6 53.4 144.5 80.6 16.9 166.3 311.1 78.2 167.7 61.5 82.4 72.5 49.6 188.0 238.2 40.4 22.0 319.6 223.8 118.1 85.4 331.9 58.4 107.7 119.2 12.2 129.1 67.1 51.5 14.6 12.5 163.5 333.3 70.7 117.6 78.4 553.4 398.4 104.7 65.0 59.2 61.2 153.0 110.3 74.7 173.0 105.4 336.7 50.8 172.1 416.8 153.4 UQCRH "QCR6, UQCR8" ENSG00000173660 "Ubiquinol-cytochrome c reductase hinge protein" P07919 1 46303698-46316776 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042574 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA042574: AB_10960998" "unprognostic (2.24e-2)" "unprognostic (6.48e-2)" "unprognostic (5.62e-2)" "unprognostic (1.06e-3)" "unprognostic (6.34e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (4.63e-5)" "unprognostic (1.31e-1)" "unprognostic (3.15e-2)" "unprognostic (2.56e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-3)" "unprognostic (2.07e-2)" "unprognostic (3.77e-1)" "unprognostic (5.14e-2)" "unprognostic (1.04e-1)" 216.1 159.7 403.2 200.3 408.4 414.5 241.5 420.6 533.0 176.6 423.5 433.1 396.6 153.6 215.7 292.8 121.1 134.9 1012.8 410.2 421.1 363.4 261.5 121.6 257.5 417.7 404.1 227.8 215.9 403.4 144.7 142.4 411.3 147.8 418.4 436.6 278.5 177.2 932.8 172.0 291.0 146.8 408.8 143.2 256.0 77.7 420.4 312.4 138.0 1033.3 349.6 237.6 188.9 408.4 766.7 456.4 514.3 945.2 529.0 720.3 1070.8 501.7 311.3 435.2 372.5 883.1 416.1 750.2 653.2 474.0 777.9 537.8 742.2 778.7 650.8 563.1 1262.1 1854.5 1320.9 1215.3 313.6 1832.0 508.1 810.8 466.3 706.7 363.4 643.0 622.6 907.5 1803.3 814.1 675.1 613.9 830.6 1884.9 3043.4 950.6 917.8 858.9 840.5 2386.6 974.1 1679.4 1008.3 1180.4 806.7 1519.3 1628.1 1346.7 507.4 2232.3 541.3 410.8 528.9 589.2 935.7 546.9 1230.5 1185.4 593.1 1432.2 625.9 171.5 372.6 249.0 214.4 332.7 281.9 544.6 307.8 283.6 481.5 433.1 346.2 313.0 69.3 221.4 297.8 318.2 340.7 620.8 403.2 408.4 420.6 533.0 410.2 421.1 417.7 404.1 411.3 408.8 420.4 408.4 249.6 105.8 148.5 26.4 523.3 457.8 703.8 1298.7 544.7 269.7 669.2 942.3 1897.2 479.0 505.3 393.6 166.8 651.5 273.8 761.5 2099.3 479.4 65.2 239.0 321.1 293.0 502.5 453.8 49.7 350.6 816.2 285.8 452.1 341.1 283.6 432.7 355.6 612.9 724.5 102.6 53.9 1148.6 612.3 711.1 410.1 69.1 308.8 516.2 489.2 12.2 606.2 408.1 365.6 22.1 22.2 419.9 789.0 284.4 703.3 710.0 944.4 1521.9 213.3 454.0 328.7 358.3 372.6 184.3 337.8 935.4 526.9 650.2 318.0 396.5 1298.2 866.4 UQCRQ "QCR8, QP-C, UQCR7" ENSG00000164405 "Ubiquinol-cytochrome c reductase complex III subunit VII" O14949 5 132866630-132868847 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1301.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3312.4;Hepatocytes: 5039.2;Proximal tubular cells: 3336.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046693, HPA053323" Approved Enhanced Mitochondria NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046693: AB_10968453, HPA053323: AB_2682112" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (4.92e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.09e-1)" "unprognostic (9.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (3.37e-2)" 226.5 378.7 277.6 91.8 283.7 132.6 189.2 309.6 391.9 151.7 293.2 313.0 220.8 147.9 211.2 332.4 138.6 78.3 1301.6 283.6 315.5 460.7 1036.6 149.0 69.1 291.2 285.6 120.0 269.4 318.5 222.8 89.0 294.9 272.9 232.2 187.4 253.8 122.2 1024.7 182.3 244.5 98.5 286.6 151.8 372.3 128.9 294.7 130.3 167.3 873.5 92.3 219.9 193.3 302.3 300.9 391.1 246.7 599.9 364.2 292.2 209.3 216.3 310.6 341.7 424.9 556.4 353.8 126.5 433.4 291.5 424.5 302.7 229.5 536.6 300.7 222.9 466.0 169.4 606.3 459.9 312.7 188.8 276.2 314.0 366.5 247.4 341.6 229.6 274.1 258.3 219.2 398.6 369.7 547.5 450.5 442.1 175.3 568.1 367.0 288.4 271.7 541.7 460.9 573.4 410.7 335.8 269.1 302.7 493.9 170.4 451.9 422.5 168.3 316.0 392.1 257.2 438.7 423.1 616.3 236.6 417.9 350.0 320.6 474.1 528.3 355.5 245.6 431.0 251.8 317.2 280.3 280.2 472.0 260.6 273.5 263.6 258.8 322.9 410.0 516.7 326.1 658.2 277.6 283.7 309.6 391.9 283.6 315.5 291.2 285.6 294.9 286.6 294.7 302.3 252.0 250.0 349.3 17.6 258.1 348.3 334.0 1046.6 235.6 97.8 575.5 657.7 3312.4 993.7 556.9 787.2 120.9 720.4 200.6 1678.3 1813.7 685.6 470.0 424.1 308.5 288.4 549.3 319.4 13.9 947.7 484.1 330.2 438.3 467.5 294.5 277.0 333.8 5039.2 771.4 72.3 17.0 1047.6 807.7 421.1 448.6 1116.6 282.4 301.6 715.1 11.2 394.7 459.2 260.6 13.6 23.5 705.7 1460.8 288.9 416.2 537.1 2476.1 3336.0 512.5 271.5 184.1 217.8 388.7 308.1 174.7 570.1 514.0 562.7 205.0 235.9 1205.6 500.2 URGCP "DKFZp666G166, DKFZp686O0457, FLJ20654, KIAA1507, URG4" ENSG00000106608 "Upregulator of cell proliferation" Q8TCY9 7 43875894-43926411 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019879, HPA020134, HPA029468" Approved Supported Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA019879: AB_1858651, HPA020134: AB_1858652, HPA029468: AB_10601831" "unprognostic (5.66e-2)" "unprognostic (1.10e-3)" "unprognostic (1.18e-1)" "unprognostic (2.75e-1)" "unprognostic (2.21e-3)" "unprognostic (2.42e-2)" "unprognostic (3.74e-2)" "unprognostic (1.26e-1)" "unprognostic (3.79e-1)" "unprognostic (2.21e-1)" "unprognostic (3.23e-3)" "unprognostic (3.71e-1)" "prognostic favorable (1.90e-4)" "unprognostic (1.56e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (1.69e-3)" 15.9 35.6 25.1 9.9 24.6 10.3 15.0 24.5 25.9 19.7 24.1 22.6 24.3 17.7 14.7 17.8 19.5 11.1 25.2 24.5 22.5 24.3 29.6 14.2 10.8 20.7 20.0 20.7 19.1 22.1 27.4 11.9 21.3 21.6 19.0 20.1 15.6 16.1 34.9 18.6 22.8 18.7 19.2 18.5 17.4 9.7 23.4 10.4 18.7 31.6 10.6 20.4 16.6 23.8 28.2 25.1 10.1 32.1 26.3 24.0 9.6 33.2 58.4 35.2 35.6 21.1 21.8 16.5 16.9 31.7 53.5 44.3 28.0 23.8 34.3 31.6 17.3 11.5 25.2 19.0 28.0 17.7 20.3 18.5 28.5 27.8 27.0 23.1 17.7 18.9 28.6 13.1 23.7 21.0 18.6 14.6 19.1 33.1 25.8 24.9 14.6 22.2 33.7 27.7 25.8 44.4 34.4 49.6 15.4 16.5 25.0 21.0 19.5 20.3 9.4 22.8 26.1 34.1 53.6 20.7 23.2 26.7 38.6 4.5 4.7 6.2 8.8 7.4 9.4 5.8 9.2 11.7 10.2 4.9 9.9 8.8 0.5 2.8 8.3 1.6 10.6 6.6 25.1 24.6 24.5 25.9 24.5 22.5 20.7 20.0 21.3 19.2 23.4 23.8 10.1 3.2 9.2 14.7 12.2 11.1 13.4 7.9 9.1 25.9 17.7 17.8 23.8 12.8 7.3 12.9 8.4 6.3 8.9 41.0 17.6 13.0 1.2 16.3 14.3 10.2 8.4 6.3 28.6 13.2 11.8 13.5 23.9 23.2 7.0 21.1 12.5 27.3 6.5 16.8 25.1 12.5 10.2 5.0 10.2 3.4 18.3 7.5 12.4 6.5 4.8 12.2 7.2 7.5 17.6 15.7 23.4 18.8 4.2 14.1 37.9 26.4 8.7 20.4 6.6 13.8 12.6 8.8 8.3 9.1 14.8 3.4 10.8 15.2 16.2 15.0 URGCP-MRPS24 ENSG00000270617 "URGCP-MRPS24 readthrough" 7 43866558-43906589 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 4.6;Club cells: 5.6;Distal tubular cells: 1.9;granulocytes: 1.3;Respiratory ciliated cells: 8.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 2.4;HBEC3-KT: 2.1;SCLC-21H: 2.5" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.69e-2)" "unprognostic (6.74e-3)" "unprognostic (2.14e-2)" "unprognostic (5.06e-2)" "unprognostic (1.80e-1)" "unprognostic (4.92e-2)" "unprognostic (5.11e-2)" "unprognostic (3.66e-1)" "unprognostic (1.51e-1)" "unprognostic (8.57e-4)" "unprognostic (1.37e-1)" "unprognostic (2.20e-5)" "unprognostic (1.82e-1)" "unprognostic (2.67e-2)" "unprognostic (2.40e-1)" "unprognostic (5.46e-2)" 0.3 0.4 0.5 0.1 0.7 0.0 0.3 0.6 1.7 0.6 0.2 0.7 0.0 0.2 0.3 0.2 0.3 0.0 0.6 0.7 0.6 1.2 0.3 0.2 0.1 0.4 0.5 0.3 0.6 0.4 0.5 0.0 0.5 0.5 0.1 0.8 0.3 0.0 0.8 0.2 0.4 0.1 0.4 0.1 0.6 0.1 0.6 0.0 0.3 0.3 0.1 0.3 0.3 0.8 0.2 0.4 0.4 0.5 0.0 0.6 0.2 0.0 0.6 0.2 0.3 1.5 0.0 0.1 0.2 0.6 2.4 0.6 0.3 2.1 0.0 1.4 0.9 1.4 0.4 0.4 0.3 1.5 0.0 0.5 0.8 0.0 0.5 0.9 0.2 0.5 0.6 0.0 0.8 1.3 0.3 0.3 0.0 0.8 0.3 0.2 0.3 0.0 0.0 0.0 2.5 0.4 0.0 0.0 0.3 0.2 0.6 0.0 0.0 0.9 0.0 0.7 0.2 0.1 0.3 0.0 0.0 0.8 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.2 0.3 0.8 0.3 0.0 0.1 0.5 0.0 0.3 0.3 0.2 0.0 0.1 0.5 0.7 0.6 1.7 0.7 0.6 0.4 0.5 0.5 0.4 0.6 0.8 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 UROS ENSG00000188690 "Uroporphyrinogen III synthase" P10746 10 125784980-125823258 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044038 Approved Approved Nucleoplasm,Cytosol NA NA 69000 "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Cytosol "HPA044038: AB_10966692" "unprognostic (8.86e-2)" "unprognostic (7.64e-2)" "unprognostic (2.77e-1)" "unprognostic (7.19e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (5.82e-2)" "unprognostic (1.27e-1)" "unprognostic (4.35e-3)" "unprognostic (4.23e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (1.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (3.93e-1)" 27.9 41.3 54.1 13.4 55.3 67.5 26.9 40.6 64.5 15.9 33.0 29.9 20.9 21.4 56.9 24.9 19.3 15.6 73.2 56.3 45.8 40.7 59.7 20.5 18.8 41.6 48.1 22.5 32.9 30.0 29.9 11.3 43.5 27.4 16.5 26.2 29.6 19.1 83.8 23.0 24.2 18.1 40.2 28.0 29.6 31.2 51.8 18.6 32.5 80.0 19.1 27.3 17.0 47.8 45.5 56.3 29.8 74.9 38.5 42.2 51.9 51.4 94.5 39.0 34.6 22.9 54.0 58.4 24.7 72.9 24.3 23.5 18.5 43.1 31.3 78.1 39.9 125.3 27.9 40.1 67.3 50.7 29.7 59.3 20.7 25.8 66.0 47.5 34.4 48.5 24.4 54.1 63.5 65.2 51.2 72.8 37.7 31.8 54.0 33.1 34.1 37.3 53.9 28.2 26.2 46.8 51.6 41.8 80.7 30.8 40.4 59.1 33.8 52.3 19.6 38.1 48.2 50.7 36.8 40.6 75.6 23.1 26.3 4.9 31.9 4.6 30.1 33.1 33.9 30.1 29.3 38.6 53.5 37.5 38.1 29.6 2.1 53.6 31.9 25.3 29.8 38.1 54.1 55.3 40.6 64.5 56.3 45.8 41.6 48.1 43.5 40.2 51.8 47.8 19.0 19.2 23.1 20.5 34.3 9.3 12.0 31.8 9.6 49.3 36.2 39.5 70.5 40.0 28.6 36.8 45.9 60.8 36.3 19.1 101.8 59.7 57.0 11.2 25.5 22.2 14.5 231.5 23.9 59.6 47.4 33.3 23.9 16.9 11.4 112.3 28.2 53.4 79.3 47.1 25.2 25.6 40.7 47.8 20.8 123.7 35.8 31.6 62.2 9.4 58.7 77.0 69.0 13.6 29.6 42.7 15.8 40.6 46.9 27.3 52.9 142.6 20.4 42.3 6.6 22.8 36.7 55.7 100.9 28.5 12.8 20.0 37.8 55.0 38.8 21.3 USE1 "D12, MDS032, p31, SLT1" ENSG00000053501 "Unconventional SNARE in the ER 1" Q9NZ43 19 17215346-17219829 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026851, HPA047562" Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 10: Non-specific - Unknown function" "HPA026851: AB_10602903, HPA047562: AB_2680089" "unprognostic (3.03e-3)" "unprognostic (2.61e-3)" "unprognostic (2.24e-2)" "unprognostic (3.09e-2)" "unprognostic (1.03e-1)" "unprognostic (2.34e-1)" "unprognostic (2.00e-1)" "unprognostic (3.04e-2)" "unprognostic (4.24e-1)" "unprognostic (2.94e-2)" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (8.14e-2)" "unprognostic (3.23e-1)" "unprognostic (6.61e-2)" "unprognostic (1.31e-2)" 33.2 40.2 48.0 20.2 50.0 28.8 30.5 48.1 57.9 30.7 45.2 30.5 17.4 24.5 19.0 25.9 24.0 20.2 47.1 48.4 49.0 31.6 42.0 25.7 28.2 49.8 49.0 31.9 43.2 14.2 22.1 15.6 49.3 26.8 10.9 11.8 38.4 14.9 56.0 28.2 25.4 14.9 48.2 39.7 31.7 19.6 48.0 25.2 24.6 36.2 18.3 29.3 24.4 53.8 34.5 20.1 10.9 45.4 36.4 34.4 37.7 24.5 28.3 27.0 33.7 26.4 40.4 23.0 55.5 33.6 9.5 19.6 9.7 33.4 9.3 49.5 44.2 42.5 37.6 28.3 74.4 47.9 37.7 47.2 17.6 23.4 46.3 30.7 18.1 55.8 27.6 77.8 28.5 41.3 46.2 35.2 21.2 26.6 70.1 36.2 12.1 89.6 31.4 27.5 29.4 25.9 27.1 39.1 42.5 10.9 25.2 74.5 26.6 17.8 17.2 32.5 30.9 87.4 86.7 30.9 47.9 76.2 30.2 43.9 58.1 18.0 54.3 51.6 61.8 139.4 80.9 65.8 71.5 128.9 115.6 86.4 10.5 54.4 38.8 87.0 85.0 66.6 48.0 50.0 48.1 57.9 48.4 49.0 49.8 49.0 49.3 48.2 48.0 53.8 34.0 32.1 27.2 6.8 48.8 45.2 53.0 48.5 44.3 24.5 48.4 58.8 45.0 30.0 30.0 16.5 18.8 45.0 32.4 47.2 72.4 37.4 39.5 20.3 35.0 28.4 13.8 19.6 9.2 62.0 35.1 37.3 32.6 24.9 48.9 35.3 34.6 48.4 40.7 11.8 8.1 35.0 26.4 39.0 29.2 137.4 48.1 29.9 21.4 3.7 33.5 41.5 28.8 17.1 12.1 31.2 53.7 26.7 34.1 38.5 51.2 118.2 22.7 34.7 39.5 39.2 62.9 20.7 25.5 29.5 34.8 75.7 36.8 42.4 31.8 38.9 USF2 "bHLHb12, FIP" ENSG00000105698 "Upstream transcription factor 2, c-fos interacting" Q15853 19 35268962-35279821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029764, HPA046567" Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Vesicles "HPA029764: AB_2673190, HPA046567: AB_2679702" "unprognostic (6.10e-3)" "unprognostic (2.27e-1)" "unprognostic (1.06e-2)" "unprognostic (5.03e-3)" "unprognostic (4.60e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "unprognostic (2.87e-1)" "unprognostic (2.10e-1)" "unprognostic (7.07e-2)" "prognostic favorable (5.12e-5)" "unprognostic (7.75e-2)" "unprognostic (8.12e-2)" "unprognostic (7.47e-2)" "unprognostic (5.75e-2)" "unprognostic (6.90e-2)" "prognostic favorable (3.28e-4)" 126.7 132.5 188.9 130.4 191.7 177.7 105.4 190.2 192.9 109.3 147.9 120.8 105.3 104.4 51.5 104.6 104.1 66.3 196.6 181.0 180.3 97.8 185.2 102.2 154.9 192.9 185.4 164.5 121.1 109.4 149.1 63.5 187.2 99.8 54.1 90.4 97.9 57.2 359.3 122.0 112.7 52.4 186.4 160.5 104.1 51.7 191.7 101.3 125.8 195.1 96.7 100.2 99.9 183.2 189.2 190.2 93.6 91.1 161.7 81.5 89.2 101.0 119.7 90.4 69.3 87.3 95.5 183.7 157.6 86.3 96.4 56.5 88.6 79.6 45.4 306.4 135.8 107.5 111.1 143.1 97.8 182.5 177.5 71.7 108.3 58.6 89.1 151.3 62.2 119.6 135.3 260.0 70.5 218.8 200.7 69.8 78.7 171.3 61.1 190.9 123.2 171.2 74.8 119.5 159.3 120.7 188.2 200.4 346.7 80.7 81.8 142.4 107.4 150.0 101.0 99.5 134.4 260.0 286.6 199.7 139.4 114.8 201.0 44.5 8.3 11.1 6.8 11.2 8.2 10.2 7.0 9.0 13.4 13.5 6.3 6.0 7.8 11.7 6.9 50.6 13.8 7.7 188.9 191.7 190.2 192.9 181.0 180.3 192.9 185.4 187.2 186.4 191.7 183.2 58.2 6.4 22.4 29.7 72.5 23.7 23.7 18.7 20.5 66.0 42.2 38.4 71.6 35.8 15.5 31.3 33.3 24.2 108.1 50.7 56.7 33.5 1.1 25.6 31.3 36.5 52.1 37.2 19.7 57.8 38.5 32.7 30.5 34.0 20.3 45.7 38.6 50.5 107.0 94.2 16.9 33.6 20.3 66.8 42.9 3.4 32.0 91.9 26.6 28.1 37.8 118.9 35.0 12.1 19.5 36.0 37.1 31.2 63.8 23.1 58.1 51.7 11.0 53.9 13.1 40.9 35.8 9.0 10.6 34.3 24.7 17.5 56.2 52.0 33.0 35.6 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 26.0 21.5 19.9 22.7 21.3 23.9 17.0 20.1 22.9 15.5 13.9 17.8 13.9 17.0 23.8 24.0 14.6 14.6 24.8 21.0 24.5 23.4 25.3 15.1 21.6 25.4 21.7 13.3 13.0 21.2 14.3 26.5 25.7 29.7 19.3 15.5 15.2 19.6 55.6 15.4 12.4 24.7 20.3 13.8 15.1 17.9 26.0 21.8 20.4 36.4 31.3 22.6 15.3 23.3 91.6 75.4 62.7 64.5 60.7 60.0 109.6 115.5 64.9 118.9 110.5 98.9 48.7 133.1 86.6 99.1 114.4 50.9 125.1 91.7 134.9 38.7 59.0 72.5 46.0 78.1 60.5 184.1 70.8 48.4 69.1 122.3 69.5 55.0 93.5 65.9 106.2 99.3 119.1 76.2 105.2 52.4 59.4 56.0 83.5 87.8 78.6 98.0 88.7 79.9 71.8 60.1 120.7 59.2 52.5 68.0 58.2 51.5 103.9 138.7 104.3 128.8 170.6 62.3 125.7 130.9 80.0 77.3 88.4 10.7 18.1 13.8 27.9 25.8 33.6 21.1 27.5 29.5 25.6 16.4 26.7 26.2 1.5 39.3 20.5 18.7 28.6 19.4 19.9 21.3 20.1 22.9 21.0 24.5 25.4 21.7 25.7 20.3 26.0 23.3 40.0 22.4 40.4 27.7 52.7 58.6 53.3 42.0 51.8 58.0 33.4 23.5 44.9 31.5 48.3 44.1 31.3 92.3 58.1 22.5 45.0 60.6 70.9 44.9 56.3 43.1 22.1 102.0 58.8 54.0 71.8 49.0 43.8 80.8 34.8 47.1 28.2 45.4 50.9 116.1 54.4 22.5 46.8 31.5 53.4 21.6 31.7 45.5 35.6 33.7 48.8 39.4 46.4 35.2 74.8 75.8 16.9 45.9 72.7 71.4 15.2 56.0 40.2 50.3 0.0 49.6 51.4 34.1 68.1 57.9 52.4 135.6 55.0 58.9 33.5 51.8 USP46 FLJ12552 ENSG00000109189 "Ubiquitin specific peptidase 46" P62068 4 52590960-52659301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Behavior, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Bipolar cells: 150.8;Early spermatids: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, CAB076369, CAB076370" Uncertain Approved "Nucleoli,Nucleoli rim" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim" "CAB076369: AB_2665642, CAB076370: AB_2665643, HPA007288: AB_1080531" "unprognostic (1.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (1.31e-1)" "unprognostic (1.41e-1)" "unprognostic (1.53e-3)" "unprognostic (1.59e-1)" "unprognostic (2.45e-2)" "unprognostic (1.80e-2)" "unprognostic (2.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (3.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" 4.4 8.6 30.4 3.3 31.2 2.9 6.4 27.4 31.5 7.6 22.4 3.9 4.4 6.5 5.4 11.5 7.0 5.3 28.6 30.8 33.3 9.9 2.9 3.9 3.7 27.9 33.9 11.0 5.2 10.4 4.6 5.3 26.7 6.9 4.0 11.5 8.3 6.7 14.5 7.5 4.2 5.0 30.4 3.3 6.0 12.3 32.5 3.4 9.3 12.5 5.5 6.0 7.4 26.8 8.1 5.7 18.0 13.3 19.1 23.8 19.8 13.0 10.5 9.5 7.9 11.5 6.2 5.4 14.9 13.0 13.4 4.7 31.6 15.1 17.2 4.7 11.1 8.4 5.3 12.8 19.1 11.2 9.4 20.4 13.9 9.7 9.1 18.4 14.2 7.4 8.3 7.4 20.3 7.4 4.8 5.9 13.3 9.0 6.8 12.0 13.1 1.1 20.3 14.8 10.8 12.9 6.4 21.5 12.9 17.1 7.9 8.2 13.3 9.2 20.1 10.9 19.9 7.5 3.7 4.2 14.2 6.7 11.6 0.7 0.4 0.1 0.7 0.4 0.5 0.4 1.2 0.6 0.9 0.4 0.2 0.2 0.1 0.4 0.3 1.4 0.4 0.3 30.4 31.2 27.4 31.5 30.8 33.3 27.9 33.9 26.7 30.4 32.5 26.8 10.0 6.4 7.2 24.2 6.4 5.4 11.2 15.2 26.2 150.8 13.7 11.7 44.9 14.3 16.4 14.7 4.2 12.1 10.7 5.2 21.5 10.8 229.8 18.4 34.9 12.5 4.2 6.7 32.6 12.0 12.5 17.8 17.3 15.6 0.0 22.9 13.6 6.8 5.8 35.3 24.3 5.9 10.2 8.4 4.6 34.1 28.9 7.9 8.8 21.5 12.9 30.0 5.2 30.2 12.6 12.5 9.9 36.1 9.5 21.1 3.9 17.1 23.8 8.7 6.6 16.2 15.9 3.2 14.4 25.9 8.2 7.7 8.0 18.3 7.1 17.7 VAPB "ALS8, VAP-B, VAP-C" ENSG00000124164 "VAMP associated protein B and C" O95292 20 58389229-58451101 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013144, CAB013722" Supported Enhanced "Endoplasmic reticulum" NA NA 240000 "Cluster 32: T-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "CAB013722: , HPA013144: AB_1858717" "unprognostic (3.28e-3)" "unprognostic (3.88e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (9.36e-2)" "unprognostic (3.15e-2)" "unprognostic (4.76e-3)" "unprognostic (2.80e-1)" "unprognostic (4.47e-2)" "unprognostic (8.06e-3)" "unprognostic (3.11e-2)" "unprognostic (2.99e-1)" "prognostic favorable (1.08e-8)" "unprognostic (1.05e-1)" "unprognostic (5.31e-1)" "unprognostic (6.34e-3)" "unprognostic (2.99e-2)" 15.7 36.4 32.1 11.2 30.4 4.2 14.2 29.6 30.1 13.7 20.3 24.2 19.6 16.4 10.3 19.3 14.9 9.7 29.4 28.8 33.5 24.8 35.0 14.1 9.6 34.6 34.0 17.9 18.9 27.9 21.0 9.2 36.2 17.8 9.9 14.3 16.2 12.3 46.4 13.0 18.2 11.6 36.4 15.0 19.0 8.8 37.0 12.2 23.3 39.6 6.7 18.1 12.9 31.5 31.0 30.4 33.6 18.0 30.3 12.5 29.5 27.0 11.2 41.0 20.1 123.0 29.0 27.2 37.7 18.3 32.3 57.6 27.1 38.9 24.6 12.8 20.2 16.5 32.2 38.9 30.2 15.5 19.8 28.9 44.4 22.8 18.7 19.8 20.5 26.7 39.5 14.9 20.0 96.7 24.5 30.6 17.7 60.2 40.0 24.2 31.3 18.0 31.6 40.7 47.1 32.6 44.7 117.0 48.0 18.4 48.0 23.2 28.6 65.8 31.9 33.3 36.9 19.9 23.1 31.4 55.7 16.8 33.8 2.1 2.3 3.1 3.9 2.4 4.5 2.8 4.6 3.2 2.3 2.3 3.3 4.8 3.7 3.7 3.0 2.3 2.7 2.6 32.1 30.4 29.6 30.1 28.8 33.5 34.6 34.0 36.2 36.4 37.0 31.5 22.5 44.8 26.8 31.6 18.7 11.7 13.5 17.2 23.9 29.7 23.6 21.1 46.5 24.3 16.6 31.3 29.2 34.8 20.7 28.6 35.2 35.1 5.0 18.2 20.9 23.2 21.7 18.7 34.3 30.5 50.3 24.0 20.4 16.0 9.5 23.3 15.7 40.3 16.1 35.3 34.7 23.4 22.4 18.5 10.0 6.1 18.6 17.3 14.2 40.3 22.8 34.3 20.6 35.2 43.7 37.5 22.4 25.2 14.0 17.7 38.9 42.9 19.1 29.7 13.1 22.2 26.0 22.0 29.4 18.2 10.5 44.5 20.5 37.4 27.6 16.6 VBP1 "PFD3, PFDN3" ENSG00000155959 "VHL binding protein 1" P61758 X 155197007-155239841 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006260, HPA023230" Approved Supported Vesicles,Cytosol NA NA 15000 "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Vesicles "CAB006260: AB_425740, HPA023230: AB_1858727" "unprognostic (1.55e-3)" "unprognostic (1.12e-3)" "unprognostic (3.35e-1)" "unprognostic (1.35e-2)" "unprognostic (3.78e-2)" "unprognostic (1.85e-3)" "unprognostic (5.31e-3)" "unprognostic (1.40e-1)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (9.80e-2)" "unprognostic (1.15e-1)" "unprognostic (5.76e-2)" "unprognostic (3.76e-2)" "unprognostic (4.54e-2)" "unprognostic (9.30e-2)" "unprognostic (3.80e-1)" 32.1 32.5 48.6 29.4 50.2 50.5 31.6 54.6 60.5 24.2 43.6 30.1 23.0 25.2 26.6 31.0 23.5 21.1 65.7 49.5 53.7 40.4 31.2 23.3 41.3 52.7 52.8 25.5 19.7 38.2 29.7 30.2 53.4 30.9 33.0 48.2 20.6 25.4 101.5 19.3 24.3 28.9 54.6 24.8 22.6 15.9 51.9 45.8 31.6 121.2 40.4 32.2 19.9 60.1 162.8 57.6 122.1 81.1 49.6 68.0 35.2 78.8 60.7 99.7 155.3 69.1 80.8 207.1 163.6 66.8 154.1 62.4 179.3 74.0 129.5 110.0 123.9 87.6 86.0 54.2 58.9 142.6 65.5 51.0 84.7 84.7 105.6 53.1 93.7 101.0 173.4 119.9 113.6 67.7 134.3 120.9 71.0 149.1 122.1 114.0 97.0 121.4 86.8 73.0 132.0 80.0 54.1 62.7 90.1 83.4 53.8 107.5 55.6 80.5 100.0 138.3 198.0 133.9 209.0 361.3 71.6 173.1 101.0 22.5 23.0 75.8 26.3 25.1 30.2 28.6 30.5 31.7 36.2 23.7 34.5 37.5 26.3 28.2 21.9 29.5 43.2 33.0 48.6 50.2 54.6 60.5 49.5 53.7 52.7 52.8 53.4 54.6 51.9 60.1 40.7 51.3 29.1 12.1 55.1 57.4 81.2 89.9 33.6 54.9 33.2 30.2 80.5 30.0 48.0 38.6 20.9 73.7 60.4 27.9 191.7 65.8 2.5 32.8 41.3 47.3 23.4 128.6 12.7 57.6 101.4 52.6 28.5 28.9 47.5 36.6 30.7 24.9 67.6 32.0 14.2 30.0 75.3 29.5 64.4 4.6 42.0 40.7 46.2 6.5 80.1 78.7 47.4 6.6 21.3 52.7 43.1 39.9 56.8 78.0 29.3 126.3 37.2 46.3 46.0 45.1 52.8 80.7 88.2 37.1 52.6 68.7 60.0 81.6 45.9 63.0 VCP "CDC48, IBMPFD, p97, TERA" ENSG00000165280 "Valosin containing protein" P55072 9 35053928-35072668 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair, Transport, Ubl conjugation pathway" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 540.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005593, HPA012728, HPA012814" Supported Enhanced Nucleoplasm,Cytosol No No 34000000 "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "CAB005593: AB_2214638, HPA012728: AB_1858730, HPA012814: AB_1858729" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.15e-2)" "prognostic favorable (7.30e-4)" "unprognostic (5.78e-2)" "unprognostic (1.87e-1)" "unprognostic (2.52e-3)" "unprognostic (1.13e-2)" "unprognostic (3.82e-2)" "unprognostic (1.81e-2)" "unprognostic (2.19e-2)" "unprognostic (3.24e-1)" "prognostic favorable (9.63e-7)" "unprognostic (1.83e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (9.11e-2)" 59.8 88.4 56.8 33.7 59.0 52.0 54.2 58.9 58.0 57.8 72.0 51.8 33.8 59.0 51.6 84.9 49.4 35.3 117.5 60.4 66.2 59.1 87.5 57.2 42.5 64.4 62.0 46.1 61.2 65.7 57.3 46.0 68.2 54.5 36.5 26.3 63.2 58.9 176.0 64.0 51.8 42.5 62.3 64.1 62.5 45.1 63.7 59.6 49.7 135.3 53.3 57.9 55.3 69.8 167.6 223.8 124.6 57.5 187.4 135.3 98.3 153.8 215.0 244.1 197.6 160.0 60.1 140.8 137.2 242.9 173.1 69.5 253.1 230.7 227.6 146.2 126.0 95.3 216.5 238.0 146.5 92.4 106.2 148.5 136.4 239.2 115.6 104.4 276.2 56.3 97.6 71.4 219.2 154.7 114.3 234.9 152.2 82.7 219.1 80.7 111.8 72.8 204.1 175.7 65.7 84.1 100.4 81.2 45.1 152.2 71.5 60.3 215.5 77.5 112.5 63.7 118.6 41.9 116.5 104.3 139.5 67.0 105.4 142.0 62.7 75.0 58.8 70.0 62.4 59.2 59.0 65.6 75.3 53.0 42.3 44.4 71.1 67.1 80.4 49.8 91.2 111.8 56.8 59.0 58.9 58.0 60.4 66.2 64.4 62.0 68.2 62.3 63.7 69.8 86.5 80.1 73.7 22.9 124.3 77.0 120.8 147.6 111.5 86.6 66.0 47.2 220.4 47.1 115.1 55.2 118.9 276.8 91.0 111.9 74.3 188.6 43.6 97.8 85.6 127.7 84.2 137.0 27.4 187.5 164.7 109.7 133.5 105.8 62.1 106.2 111.0 126.0 133.1 74.0 27.7 108.3 89.5 57.9 65.6 47.0 83.9 81.5 76.5 16.9 159.6 88.7 54.6 18.6 31.4 247.9 69.0 86.9 267.6 118.3 77.2 113.4 102.5 90.0 138.1 74.1 154.9 144.5 118.7 126.2 90.6 540.6 105.4 129.6 96.4 135.6 WBP2 "GRAMD6, WBP-2" ENSG00000132471 "WW domain binding protein 2" Q969T9 17 75845699-75856507 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 321.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065682, HPA068819" Approved Supported Nucleoplasm,Cytosol No No 440000 "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "HPA065682: AB_2685530, HPA068819: AB_2686042" "unprognostic (1.74e-1)" "unprognostic (1.71e-2)" "unprognostic (3.17e-2)" "unprognostic (2.85e-1)" "unprognostic (8.39e-2)" "unprognostic (7.12e-2)" "unprognostic (8.89e-2)" "unprognostic (3.09e-1)" "unprognostic (2.68e-3)" "unprognostic (1.58e-1)" "unprognostic (4.54e-3)" "unprognostic (6.18e-2)" "unprognostic (2.21e-1)" "unprognostic (5.86e-3)" "unprognostic (1.30e-1)" "unprognostic (2.13e-2)" "unprognostic (1.76e-1)" 113.2 223.6 239.5 57.1 238.6 82.7 114.1 225.1 340.9 103.2 163.6 109.7 65.2 84.6 44.3 94.7 106.1 62.8 183.1 243.0 242.2 125.7 184.4 118.1 60.9 293.9 256.8 113.9 134.5 100.7 116.0 55.4 286.4 103.5 39.0 129.7 137.7 73.5 250.2 131.3 85.7 52.0 226.4 112.5 123.2 95.4 259.8 49.2 83.8 91.9 51.8 97.8 94.7 256.6 104.6 119.9 43.4 52.5 88.0 87.2 57.9 32.7 102.1 74.3 91.8 59.7 104.2 52.9 81.9 47.0 232.2 61.0 45.2 100.9 66.3 40.1 90.4 97.7 66.4 97.6 182.2 40.8 161.6 96.4 94.6 89.4 120.8 127.0 143.8 82.1 68.2 156.7 60.2 107.3 85.8 85.8 37.3 70.8 78.8 57.8 85.4 101.5 109.7 62.3 72.6 114.8 58.5 99.9 163.1 76.3 134.9 102.1 84.3 75.8 66.1 73.6 52.3 145.4 109.6 38.8 212.5 38.3 54.9 239.9 85.0 288.7 53.8 102.6 59.1 68.9 59.5 54.6 54.8 55.3 55.8 47.5 308.9 57.4 136.4 42.0 77.4 93.2 239.5 238.6 225.1 340.9 243.0 242.2 293.9 256.8 286.4 226.4 259.8 256.6 73.5 83.3 79.0 34.9 62.7 60.9 127.2 85.9 30.1 109.7 75.2 53.3 73.2 55.8 59.9 53.3 75.0 64.9 45.9 65.9 162.4 124.3 264.5 41.5 21.7 63.4 33.6 124.0 23.6 188.6 65.1 43.5 34.1 44.3 67.0 40.0 54.3 61.9 138.4 112.7 23.4 48.9 71.2 65.5 71.2 321.1 59.4 90.2 60.5 23.4 90.8 104.8 52.5 21.1 38.6 126.5 72.6 53.8 35.6 120.2 88.4 100.7 44.8 120.7 26.3 43.8 44.9 45.5 25.7 24.8 80.0 184.7 51.7 62.5 27.1 95.6 WDR59 FLJ12270 ENSG00000103091 "WD repeat domain 59" Q6PJI9 16 74871362-75000173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041084, HPA048218" Approved Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA041084: AB_10793867, HPA048218: AB_2680318" "unprognostic (3.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.65e-2)" "unprognostic (4.16e-2)" "unprognostic (6.14e-2)" "unprognostic (3.99e-1)" "unprognostic (2.28e-2)" "unprognostic (8.83e-2)" "unprognostic (3.43e-1)" "unprognostic (2.37e-2)" "unprognostic (4.21e-3)" "unprognostic (3.25e-3)" "unprognostic (2.05e-2)" "unprognostic (9.08e-2)" "unprognostic (3.88e-2)" "unprognostic (1.78e-1)" "unprognostic (5.61e-2)" 11.6 19.0 18.2 13.8 22.1 16.1 14.2 18.2 21.3 19.2 15.5 15.3 13.1 16.1 21.1 17.3 14.9 9.7 17.0 17.9 20.0 17.3 35.7 11.1 12.7 19.0 19.3 22.4 16.9 22.6 22.9 14.1 19.8 15.8 14.0 37.9 14.1 11.6 24.8 21.1 16.4 13.2 17.2 15.3 14.2 13.9 20.6 22.3 22.9 17.4 16.0 14.5 17.3 28.5 15.6 23.8 27.1 25.8 20.8 18.7 22.9 9.8 17.0 20.7 23.5 32.3 27.1 21.8 10.6 18.3 19.3 24.6 21.7 23.4 29.3 13.2 23.1 27.9 16.3 52.5 12.6 20.4 32.7 21.8 18.7 25.1 23.7 26.7 21.7 52.5 42.0 10.6 9.9 46.1 31.4 36.4 21.6 34.0 9.7 31.3 11.9 18.3 22.2 13.9 16.5 18.2 28.0 16.2 12.6 28.5 24.5 17.8 19.0 12.9 19.6 14.8 8.5 20.1 29.3 47.2 22.8 14.1 14.3 0.7 0.7 0.7 1.0 0.4 3.4 1.9 1.9 1.5 0.4 1.1 1.2 1.4 0.7 1.0 0.8 0.7 1.0 0.4 18.2 22.1 18.2 21.3 17.9 20.0 19.0 19.3 19.8 17.2 20.6 28.5 9.8 16.0 16.5 77.1 15.0 22.4 20.0 12.7 21.6 38.8 15.0 16.3 17.6 21.5 15.0 22.0 62.6 34.4 9.6 13.1 9.8 13.0 37.4 13.1 14.6 11.8 22.1 21.0 41.5 9.6 16.5 13.6 17.3 20.1 13.3 22.4 17.9 24.6 10.8 20.2 53.8 11.9 12.2 13.2 17.1 79.2 13.4 12.7 8.8 29.0 15.3 11.9 14.4 65.9 88.8 11.9 14.0 11.7 5.9 24.1 17.0 19.6 16.7 55.5 19.7 17.1 9.7 17.7 19.1 16.5 24.2 47.3 15.3 13.8 16.8 23.4 WIPI2 "ATG18B, ATG21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984" ENSG00000157954 "WD repeat domain, phosphoinositide interacting 2" Q9Y4P8 7 5190196-5233840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 255.9;Spermatocytes: 233.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019852, HPA021488" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoplasm "HPA019852: AB_1846589, HPA021488: AB_1846591" "unprognostic (5.79e-2)" "unprognostic (1.47e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (7.69e-5)" "unprognostic (1.96e-3)" "unprognostic (9.27e-3)" "unprognostic (4.60e-3)" "unprognostic (4.96e-2)" "unprognostic (6.60e-2)" "unprognostic (4.23e-1)" "prognostic favorable (9.78e-4)" "unprognostic (1.20e-1)" "prognostic favorable (2.05e-6)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (7.41e-2)" "unprognostic (6.98e-2)" 31.1 30.9 38.8 22.9 40.7 47.0 30.8 35.2 41.8 27.3 37.1 33.9 24.7 32.1 26.3 35.8 29.0 23.2 38.0 42.8 38.6 32.2 35.7 26.4 30.2 36.3 39.1 28.2 37.1 38.2 30.6 32.8 38.7 28.7 20.2 19.1 43.5 28.2 41.3 47.1 26.7 26.8 37.0 29.6 33.6 53.8 38.7 36.8 27.4 45.0 29.2 27.1 30.0 39.8 67.5 42.1 40.4 69.4 60.7 63.3 62.0 58.7 66.9 61.2 64.2 41.2 60.9 47.7 43.9 73.8 76.0 48.2 41.2 47.8 47.4 24.9 64.1 32.7 39.7 45.8 59.9 51.8 34.4 66.9 56.4 69.7 38.3 60.9 86.3 64.3 94.2 41.9 56.2 69.9 39.6 90.0 84.3 35.9 61.1 64.3 57.7 79.5 40.4 32.3 50.3 75.4 43.0 72.8 52.4 67.3 44.8 97.2 69.2 38.9 80.9 65.6 44.4 75.0 75.2 54.7 63.4 59.3 58.8 0.4 4.7 13.6 4.4 6.0 2.8 5.7 5.8 8.0 4.2 6.2 7.5 4.7 9.1 2.6 4.2 6.4 9.0 2.2 38.8 40.7 35.2 41.8 42.8 38.6 36.3 39.1 38.7 37.0 38.7 39.8 40.2 38.5 31.5 16.3 51.6 54.9 39.5 13.9 39.3 71.5 49.4 50.5 37.0 42.9 17.6 18.4 62.6 89.4 62.7 42.6 72.4 43.0 195.8 50.0 38.1 37.9 39.5 125.0 19.7 41.8 96.6 43.1 34.7 48.0 31.1 54.8 54.7 60.4 69.1 47.1 19.6 42.6 18.3 61.4 44.8 255.9 42.6 55.9 44.4 20.6 64.5 89.5 44.3 13.6 23.5 55.6 37.0 56.1 67.7 97.7 48.7 80.6 26.4 52.8 52.6 39.7 39.4 233.0 117.3 49.8 71.0 150.8 46.8 44.1 43.0 69.8 WRNIP1 "bA420G6.2, CFAP93, FAP93, FLJ22526, WHIP" ENSG00000124535 "WRN helicase interacting protein 1" Q96S55 6 2765393-2786952 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031752, HPA031753" Enhanced Approved Nucleoplasm No No "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA031752: AB_10603004, HPA031753: AB_2674028" "unprognostic (5.52e-2)" "unprognostic (5.95e-2)" "unprognostic (6.83e-3)" "unprognostic (8.35e-3)" "unprognostic (7.66e-2)" "unprognostic (7.10e-2)" "unprognostic (5.63e-3)" "unprognostic (3.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.73e-2)" "unprognostic (1.81e-1)" "unprognostic (6.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.37e-1)" "unprognostic (2.61e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" 23.7 31.1 45.6 22.6 47.0 49.0 28.8 47.8 46.8 29.2 46.2 29.7 23.6 26.7 37.1 48.3 35.6 24.6 39.5 47.8 46.7 35.7 33.0 30.3 34.7 44.4 44.8 30.1 43.9 46.4 43.1 43.3 43.5 28.5 29.1 45.8 46.1 26.8 44.0 37.2 27.4 23.8 43.6 28.7 29.1 31.5 47.4 43.9 39.0 76.3 34.7 32.1 31.7 45.1 86.8 42.7 42.5 70.1 44.1 37.7 56.5 38.9 54.2 69.8 69.2 67.8 39.4 77.4 103.1 50.4 75.6 65.9 70.2 78.1 67.8 77.9 77.5 80.9 50.3 107.4 50.1 51.4 53.8 38.7 62.7 64.4 69.5 48.5 89.8 71.8 62.8 27.2 51.6 84.5 76.7 92.7 36.5 59.3 52.5 60.3 62.2 78.4 75.3 52.5 127.8 36.5 45.9 46.1 93.7 66.7 59.4 57.1 49.4 52.1 39.4 45.8 95.8 34.8 65.3 59.8 20.4 55.0 72.1 9.4 1.6 2.3 4.0 1.8 1.2 2.3 2.7 2.8 1.3 1.3 3.1 3.0 0.7 2.6 0.9 2.6 4.2 1.4 45.6 47.0 47.8 46.8 47.8 46.7 44.4 44.8 43.5 43.6 47.4 45.1 16.4 19.2 14.6 14.0 12.4 32.5 13.4 20.1 23.9 24.8 22.3 19.4 23.7 24.3 12.3 11.0 8.4 30.4 11.8 29.6 3.9 14.5 45.0 21.9 19.7 20.9 39.7 26.1 23.5 13.5 25.6 15.1 11.7 17.5 9.5 12.7 28.2 25.0 12.4 8.4 20.8 21.2 24.4 16.2 17.9 13.4 22.4 12.4 21.4 23.4 15.0 20.0 10.3 26.2 23.0 18.0 16.3 22.2 10.2 18.5 14.8 13.7 24.1 17.4 6.6 19.9 17.8 22.1 23.9 32.4 32.1 25.4 12.5 20.5 25.0 16.3 WSB2 "MGC10210, SBA2" ENSG00000176871 "WD repeat and SOCS box containing 2" Q9NYS7 12 118032687-118062430 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052606 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052606: AB_2681882" "unprognostic (5.02e-3)" "unprognostic (4.57e-2)" "unprognostic (4.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.42e-3)" "unprognostic (4.66e-3)" "unprognostic (7.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.93e-1)" "unprognostic (4.05e-1)" "unprognostic (2.92e-1)" "unprognostic (2.66e-1)" "unprognostic (2.79e-1)" "unprognostic (2.42e-2)" 33.8 46.8 94.4 29.8 102.1 17.6 20.2 85.2 117.5 19.6 53.2 44.7 35.3 18.7 23.8 53.0 17.9 25.3 55.8 103.0 83.8 35.5 36.6 31.5 24.1 100.3 106.3 13.8 36.7 43.0 36.1 19.2 96.4 26.6 45.3 38.9 20.9 26.4 102.7 23.0 39.0 35.7 95.2 17.7 33.0 18.6 99.4 20.8 46.5 163.3 28.3 45.6 21.1 95.4 49.3 78.2 55.2 93.5 81.1 46.7 39.1 129.3 95.9 138.6 82.8 41.5 66.4 7.1 42.6 168.7 77.4 25.8 46.6 78.6 98.7 90.7 29.6 27.5 36.7 39.0 85.7 16.2 71.5 62.7 77.7 75.0 51.6 148.7 72.3 48.5 83.2 12.5 143.8 73.2 10.3 9.9 32.2 110.7 48.2 29.3 57.5 2.2 81.9 211.5 58.5 87.3 100.1 21.8 69.9 54.7 75.0 37.3 113.7 164.6 68.7 53.1 158.8 21.6 14.6 13.4 148.8 20.3 266.9 9.7 5.0 11.5 4.5 7.5 4.0 0.7 4.4 4.7 3.5 1.8 1.9 3.4 5.4 3.4 5.2 4.1 5.1 1.8 94.4 102.1 85.2 117.5 103.0 83.8 100.3 106.3 96.4 95.2 99.4 95.4 17.1 25.6 15.7 14.7 5.9 16.6 39.4 16.4 5.2 21.0 20.2 10.3 33.7 24.3 14.1 20.2 4.2 10.0 11.8 75.1 21.5 37.4 2.0 19.5 23.6 16.7 72.7 7.4 45.9 85.1 24.3 19.6 23.0 31.5 7.0 13.1 17.2 36.4 34.7 57.2 31.9 40.7 22.4 51.8 18.4 4.7 7.5 23.5 28.4 18.7 34.8 34.1 11.3 18.1 30.7 89.6 44.5 17.3 6.2 53.4 47.7 35.6 7.2 14.1 13.1 21.8 26.0 3.2 5.1 17.8 18.6 17.2 13.1 44.8 25.8 86.9 ZC3HC1 NIPA ENSG00000091732 "Zinc finger C3HC-type containing 1" Q86WB0 7 130018287-130051451 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019089, HPA024023" Enhanced Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA019089: AB_1858976, HPA024023: AB_1858977" "unprognostic (7.14e-3)" "unprognostic (4.07e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (1.89e-1)" "unprognostic (3.39e-2)" "prognostic unfavorable (1.02e-6)" "unprognostic (2.11e-1)" "unprognostic (1.11e-3)" "unprognostic (1.48e-1)" "unprognostic (1.12e-2)" "unprognostic (2.91e-1)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (5.11e-2)" "unprognostic (2.60e-2)" "unprognostic (1.53e-1)" 8.4 12.4 11.2 7.3 11.3 4.7 8.4 10.9 11.4 9.1 11.9 9.5 5.4 9.3 8.6 7.4 8.3 5.7 16.5 11.1 12.1 11.8 14.1 6.3 10.6 11.4 11.5 9.3 7.5 11.6 7.5 8.4 11.4 8.3 7.2 5.8 7.1 7.0 32.7 6.3 7.6 11.5 11.4 12.5 8.7 15.6 12.1 10.4 7.4 29.1 10.6 9.1 7.6 11.8 15.2 24.8 30.3 35.1 17.2 15.5 20.6 19.5 23.5 36.5 36.3 29.7 25.5 34.2 13.7 24.4 48.5 13.4 40.1 29.2 35.0 22.7 34.2 24.1 21.4 29.1 27.7 27.4 22.9 18.4 21.2 38.1 24.2 20.1 39.5 28.9 73.7 11.7 35.5 26.5 33.2 51.9 62.5 26.0 28.0 31.0 23.6 29.5 37.0 10.7 19.3 34.3 27.5 39.4 30.7 42.9 17.3 28.6 17.6 24.2 11.5 20.5 32.8 22.9 36.8 44.7 37.8 34.9 41.2 34.5 24.6 23.8 26.0 29.4 29.5 39.3 26.6 27.5 31.2 37.1 35.2 27.7 2.0 29.5 28.3 18.6 30.8 24.6 11.2 11.3 10.9 11.4 11.1 12.1 11.4 11.5 11.4 11.4 12.1 11.8 5.2 6.4 2.3 12.4 8.8 1.5 5.4 16.0 11.4 6.1 4.3 5.8 13.5 4.3 7.5 7.3 0.0 19.2 4.8 2.3 17.6 12.8 3.3 3.1 5.5 8.6 3.6 5.2 13.8 9.7 16.9 8.1 4.1 2.6 4.5 12.4 11.4 9.1 9.0 6.7 15.7 4.2 16.2 5.0 3.0 5.2 8.7 4.3 1.8 9.4 11.6 6.9 9.2 11.6 12.4 8.9 7.7 6.4 9.1 2.3 2.6 22.1 8.9 5.9 0.0 7.4 8.3 42.0 22.9 5.0 1.7 7.4 7.0 9.4 4.9 2.2 ZCRB1 "MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19" ENSG00000139168 "Zinc finger CCHC-type and RNA binding motif containing 1" Q8TBF4 12 42312086-42326257 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 219.4" "Cell type enhanced" "Detected in all" "Early spermatids: 889.2;Spermatocytes: 527.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.75e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.60e-2)" "unprognostic (9.28e-2)" "unprognostic (7.92e-3)" "prognostic unfavorable (5.33e-7)" "unprognostic (4.31e-2)" "unprognostic (1.85e-2)" "prognostic favorable (7.33e-4)" "unprognostic (3.11e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-6)" "unprognostic (1.39e-2)" "unprognostic (4.33e-2)" "unprognostic (5.32e-3)" "unprognostic (9.44e-2)" 46.6 52.7 110.2 31.1 117.2 37.4 43.9 114.2 219.4 30.2 99.0 48.7 35.7 35.6 66.8 40.3 38.6 38.9 61.8 106.5 119.6 51.3 57.3 27.5 44.3 123.6 116.6 41.3 62.9 43.9 40.8 33.3 126.9 42.8 30.1 39.7 44.8 40.6 128.9 34.4 35.6 30.1 121.8 31.4 46.9 89.7 114.7 43.5 45.0 91.5 41.1 41.9 30.4 125.6 94.8 69.4 76.0 99.2 67.4 102.2 74.1 77.6 86.8 59.4 57.4 60.6 110.7 59.5 152.2 74.9 83.9 58.6 46.6 78.8 87.2 162.6 96.3 94.4 55.2 58.0 96.8 103.4 81.2 68.4 87.9 58.6 98.7 140.8 81.2 153.7 91.2 120.0 85.6 61.8 146.8 129.7 83.3 233.0 91.5 82.4 140.6 128.8 97.8 52.0 79.9 75.0 105.6 72.9 109.0 84.8 175.1 84.8 76.6 86.8 104.1 82.2 76.2 118.1 120.6 222.3 129.7 366.4 41.2 79.3 33.2 65.0 35.4 42.0 45.0 68.2 47.7 43.8 55.5 60.3 39.8 46.8 22.1 51.1 44.0 67.6 82.7 40.9 110.2 117.2 114.2 219.4 106.5 119.6 123.6 116.6 126.9 121.8 114.7 125.6 58.8 60.9 67.5 13.1 54.5 45.4 82.0 108.8 56.3 43.2 90.1 129.8 152.9 82.9 83.5 57.0 25.0 143.6 53.8 44.1 217.2 139.0 889.2 113.6 76.4 68.8 48.6 35.9 13.5 200.7 141.5 67.2 35.7 88.6 53.7 39.9 61.4 114.0 111.4 38.7 14.7 82.2 73.2 76.8 69.9 159.6 112.8 61.4 71.2 9.4 103.4 122.8 82.4 15.1 27.4 156.1 52.2 100.1 59.1 82.3 62.6 249.8 113.2 51.8 72.3 63.7 129.7 527.1 185.3 53.6 41.2 87.2 56.6 85.7 75.4 90.0 ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type palmitoyltransferase 16" Q969W1 10 97446170-97457370 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: AB_10794757, HPA040214: AB_2676886" "unprognostic (4.44e-2)" "unprognostic (3.14e-2)" "unprognostic (3.34e-1)" "unprognostic (1.20e-2)" "unprognostic (8.75e-2)" "unprognostic (8.35e-3)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (6.34e-2)" "unprognostic (1.93e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-1)" 15.6 14.9 17.8 10.2 18.5 6.8 16.3 20.3 21.9 15.0 16.4 17.1 14.3 16.4 18.5 19.9 12.2 9.9 22.1 18.1 16.5 25.1 30.3 20.8 11.3 17.2 17.8 15.9 22.8 25.5 16.7 21.6 16.4 18.3 17.3 17.4 24.2 12.1 25.8 13.1 14.7 16.6 16.1 14.5 24.1 17.3 18.8 12.6 16.0 27.9 15.1 17.1 15.3 16.7 50.7 57.4 37.9 47.1 58.7 40.4 38.7 54.6 72.1 61.2 58.4 45.7 43.6 44.4 60.1 79.8 53.4 58.0 48.2 76.7 54.2 43.7 56.0 28.5 39.8 44.3 47.4 34.0 39.7 45.7 49.8 71.6 51.3 66.3 63.9 40.4 23.1 32.8 79.0 48.4 51.8 46.0 29.9 45.8 49.5 34.0 38.6 40.9 51.9 23.2 18.4 25.9 33.2 33.7 30.6 37.7 44.6 32.9 39.6 38.2 35.0 25.0 64.7 29.2 53.0 26.9 44.1 51.7 20.7 0.3 11.1 11.1 7.2 11.9 8.1 9.0 12.5 11.5 15.7 10.6 10.0 10.1 0.5 14.5 11.8 12.0 11.1 6.8 17.8 18.5 20.3 21.9 18.1 16.5 17.2 17.8 16.4 16.1 18.8 16.7 6.2 19.2 23.1 3.9 9.0 5.2 18.9 31.8 14.8 15.8 13.6 9.3 10.1 14.3 27.6 12.9 4.2 39.8 10.3 11.5 25.4 35.5 24.8 7.0 13.3 11.3 7.2 11.6 8.2 32.3 67.2 13.7 10.2 10.9 7.0 13.3 7.5 19.5 24.6 13.5 9.2 18.9 28.5 7.3 5.9 7.6 8.7 9.3 3.6 9.4 18.4 14.9 15.5 11.1 8.4 31.5 12.1 3.8 17.1 20.0 18.9 22.2 8.3 13.0 6.6 5.2 12.2 20.1 12.9 13.8 4.3 37.9 7.2 10.9 20.9 19.3 ZFR "SPG71, ZFR1" ENSG00000056097 "Zinc finger RNA binding protein" Q96KR1 5 32354350-32444740 "Predicted intracellular proteins" "Developmental protein, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016666 Supported Approved Nucleoplasm NA NA 8100 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA016666: AB_1859060" "unprognostic (7.45e-3)" "unprognostic (8.46e-2)" "unprognostic (4.07e-3)" "unprognostic (4.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.38e-1)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (1.58e-1)" "unprognostic (3.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.47e-2)" "unprognostic (5.46e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-1)" 26.6 28.3 32.2 21.8 36.4 30.9 26.8 32.5 37.6 26.6 23.9 22.1 18.5 27.9 21.7 26.0 27.9 23.6 34.4 34.4 32.2 29.5 24.9 19.5 26.7 31.8 32.2 38.4 26.0 31.3 14.2 35.5 32.2 26.2 22.5 36.7 27.7 24.7 42.4 16.1 21.0 27.4 33.0 22.6 21.2 30.2 32.6 31.6 34.1 41.3 26.3 28.7 17.3 36.8 45.1 65.8 75.4 47.2 81.4 59.3 65.8 68.0 57.3 70.5 50.3 65.9 39.0 65.7 43.2 66.8 92.0 34.4 99.0 48.1 98.4 62.4 55.3 80.5 66.9 65.3 71.2 83.7 63.6 56.7 59.1 74.7 135.8 63.9 53.9 31.9 82.0 53.9 73.1 34.0 73.7 35.4 55.5 47.3 48.7 59.2 101.3 36.1 52.7 73.1 41.9 44.2 101.1 58.2 60.8 53.1 36.1 102.0 61.4 69.5 65.0 51.9 57.4 26.7 50.3 72.6 51.4 66.2 86.2 35.3 15.5 19.8 15.6 24.2 18.1 16.6 14.9 16.1 17.3 13.1 14.2 14.3 10.1 22.9 24.9 9.1 15.1 13.2 32.2 36.4 32.5 37.6 34.4 32.2 31.8 32.2 32.2 33.0 32.6 36.8 48.0 51.3 55.4 80.0 55.1 26.0 70.6 47.0 61.5 61.2 39.4 34.9 108.7 34.3 63.7 31.3 22.9 40.1 51.4 28.3 49.0 51.7 53.1 47.7 62.1 51.6 39.5 36.6 109.5 35.9 31.3 66.0 34.1 48.6 76.5 50.4 40.4 35.8 32.7 77.4 98.5 26.1 52.9 35.8 31.3 35.6 53.1 47.3 30.2 74.0 53.9 70.8 52.5 117.6 171.4 44.9 39.6 60.9 52.3 69.8 28.7 45.6 56.3 55.4 39.5 81.2 70.9 118.5 71.8 53.1 24.6 55.5 50.1 65.3 34.1 55.7 ZMAT5 "SNRNP20, ZC3H19" ENSG00000100319 "Zinc finger matrin-type 5" Q9UDW3 22 29730956-29767011 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004858 Approved Supported Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004858: AB_1080657" "unprognostic (2.14e-1)" "unprognostic (8.03e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-3)" "unprognostic (6.04e-3)" "unprognostic (5.69e-2)" "unprognostic (5.75e-2)" "unprognostic (3.71e-2)" "unprognostic (2.04e-1)" "unprognostic (2.15e-2)" "unprognostic (1.03e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-1)" "unprognostic (2.62e-1)" "unprognostic (4.10e-2)" 14.3 26.0 25.8 10.6 26.4 14.2 14.5 26.5 34.9 17.1 25.9 19.6 12.2 18.0 19.8 21.1 20.5 10.0 25.5 25.3 26.0 21.3 26.8 13.7 15.0 27.5 26.5 16.2 20.4 23.0 10.6 8.4 25.5 19.2 7.2 7.8 18.2 16.6 37.1 18.1 14.4 13.8 26.0 19.9 20.1 10.6 27.2 17.8 19.1 24.5 12.2 19.0 15.8 26.8 17.9 22.1 19.3 37.5 23.7 26.2 8.7 19.4 23.9 28.5 34.7 19.4 11.0 12.2 18.9 20.8 22.0 16.5 16.5 19.9 18.6 39.2 36.3 46.9 10.8 36.3 43.8 21.6 14.8 22.7 30.2 36.5 22.2 24.2 30.4 19.0 12.3 25.9 23.8 26.7 31.0 22.5 7.2 34.7 25.9 37.1 34.2 32.6 22.8 10.9 14.8 27.4 18.1 22.4 27.9 10.9 33.7 30.0 19.4 38.8 19.4 26.4 29.2 24.0 20.5 20.4 29.9 25.6 27.9 48.1 84.6 95.3 46.1 94.6 47.3 61.6 47.7 48.6 73.9 60.3 41.8 49.1 69.5 60.8 94.7 57.6 61.0 65.3 25.8 26.4 26.5 34.9 25.3 26.0 27.5 26.5 25.5 26.0 27.2 26.8 17.0 16.0 20.8 6.2 14.6 9.6 21.0 32.0 10.2 12.7 16.2 22.6 1.4 17.2 20.4 14.7 18.8 21.5 11.3 16.4 33.2 35.3 0.9 13.8 14.3 15.2 14.4 8.6 3.7 27.3 18.1 15.9 13.3 10.4 33.7 13.0 15.0 17.1 45.1 5.0 5.1 19.4 24.4 21.4 17.9 3.0 15.8 22.1 12.4 3.7 27.7 26.0 34.0 6.0 6.5 31.7 18.1 21.8 14.9 12.4 27.8 40.0 19.3 21.4 32.9 15.1 40.0 11.0 22.8 14.0 11.8 14.1 18.0 18.2 14.4 18.9 ZNF419 "ZAPHIR, ZNF419A" ENSG00000105136 "Zinc finger protein 419" Q96HQ0 19 57487711-57496098 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 31.9" "HPA003152, HPA003274" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA003152: AB_1080716, HPA003274: AB_1080714" "unprognostic (3.50e-2)" "unprognostic (1.40e-5)" "unprognostic (1.12e-1)" "unprognostic (2.63e-2)" "unprognostic (2.55e-2)" "unprognostic (8.26e-2)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (3.18e-1)" "unprognostic (1.33e-1)" "unprognostic (8.55e-5)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.20e-1)" "unprognostic (2.42e-1)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.53e-5)" 6.0 8.7 10.0 4.6 10.1 3.0 6.2 10.7 12.6 4.8 9.9 6.3 3.8 5.3 9.7 4.7 6.2 3.5 8.2 10.0 10.1 8.1 6.6 7.0 7.4 9.4 8.9 7.8 4.6 9.1 13.4 6.1 8.8 8.9 3.6 11.1 6.4 6.3 10.4 7.4 6.2 4.0 8.9 10.6 5.3 5.3 10.2 8.0 10.8 7.8 8.9 5.4 4.6 10.1 5.4 6.0 10.3 10.5 4.7 7.1 8.9 6.4 8.8 5.8 31.9 3.8 3.4 1.8 5.1 4.5 5.2 1.6 4.9 13.3 8.0 0.5 22.4 8.3 9.1 4.2 16.8 6.5 6.0 9.7 19.3 5.8 13.8 12.0 6.4 8.0 0.9 1.3 7.3 0.9 10.9 6.7 6.8 0.7 7.9 10.1 9.9 7.6 6.3 11.5 8.4 9.4 6.5 6.0 6.2 8.8 5.3 9.7 6.6 7.0 7.7 2.5 5.6 15.2 18.0 4.5 5.6 3.5 5.7 4.5 2.7 6.1 5.2 3.3 8.9 14.3 8.9 6.6 4.7 15.8 13.8 7.4 3.2 9.7 2.7 3.4 6.5 4.4 10.0 10.1 10.7 12.6 10.0 10.1 9.4 8.9 8.8 8.9 10.2 10.1 3.1 0.0 5.3 3.6 7.2 4.1 5.7 4.9 2.8 8.1 4.3 5.2 5.3 4.3 5.2 7.3 6.2 5.0 4.2 1.3 0.0 5.8 0.3 2.0 2.1 4.8 1.2 2.5 3.3 1.8 2.4 3.7 0.5 1.7 4.5 7.4 5.7 4.6 3.2 10.1 2.8 1.8 8.2 3.2 1.7 0.5 1.8 1.8 5.4 0.0 4.1 6.8 7.2 3.5 1.9 2.5 2.8 5.7 1.6 9.0 2.0 1.9 1.8 9.5 6.6 2.9 3.3 4.9 10.4 2.1 3.8 8.3 4.8 4.2 1.8 5.6 ZNF680 FLJ90430 ENSG00000173041 "Zinc finger protein 680" Q8NEM1 7 64519878-64563075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 116.9;Oligodendrocytes: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA003173 Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA003173: AB_1080744" "unprognostic (1.65e-1)" "unprognostic (3.21e-2)" "unprognostic (6.88e-2)" "unprognostic (7.41e-2)" "unprognostic (1.52e-3)" "unprognostic (3.62e-2)" "unprognostic (1.79e-1)" "unprognostic (2.07e-1)" "unprognostic (1.07e-2)" "unprognostic (1.20e-1)" "unprognostic (2.46e-1)" "unprognostic (5.72e-2)" "unprognostic (1.35e-1)" "unprognostic (8.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (8.05e-3)" 5.9 13.7 8.8 3.8 10.6 2.4 13.1 15.0 15.5 6.1 3.3 3.8 2.8 4.9 5.7 3.6 5.0 5.3 11.3 8.5 9.4 8.4 20.1 4.9 6.5 9.3 10.4 10.9 4.8 3.7 4.0 4.6 9.7 10.1 5.1 4.8 4.2 5.4 11.6 5.8 3.3 4.5 9.6 6.7 6.3 4.2 10.1 6.6 24.9 15.2 5.4 4.5 4.1 12.4 5.6 3.2 12.8 15.3 6.2 6.9 8.0 4.4 3.6 7.9 9.8 4.4 10.6 10.6 10.7 4.2 9.0 3.8 10.5 4.9 12.9 2.0 7.4 8.1 6.7 4.0 2.6 10.8 7.1 4.6 5.8 7.0 7.9 9.9 7.5 14.6 14.8 0.0 11.1 4.4 16.8 17.1 15.0 5.0 3.9 13.0 12.7 32.1 10.8 17.6 10.1 13.8 13.5 12.7 4.9 23.5 12.7 4.6 4.0 9.6 4.8 4.5 7.8 9.1 12.3 29.9 0.5 9.8 8.6 2.8 0.5 0.6 1.5 0.7 1.2 2.2 2.1 1.8 0.9 1.5 2.2 2.1 0.2 4.6 0.6 0.7 0.6 0.8 8.8 10.6 15.0 15.5 8.5 9.4 9.3 10.4 9.7 9.6 10.1 12.4 10.2 12.8 5.1 116.9 15.4 4.2 10.7 9.4 19.9 12.5 17.5 9.5 13.3 14.3 11.6 25.8 4.2 12.0 11.5 2.8 9.8 8.9 0.9 8.9 9.1 11.0 0.0 7.2 57.7 9.1 10.7 13.4 11.7 6.4 7.0 34.0 23.9 21.5 5.3 1.7 60.5 4.4 16.2 10.1 6.4 2.4 27.7 6.2 7.2 41.2 7.3 23.8 23.7 59.8 89.2 5.8 3.1 22.2 6.3 9.5 3.1 7.1 6.8 9.3 19.7 15.2 9.7 13.7 15.1 6.5 5.3 7.1 11.2 16.5 5.3 9.4 ZNF76 "D6S229E, Zfp523, ZNF523" ENSG00000065029 "Zinc finger protein 76" P36508 6 35258909-35295985 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030090, HPA030091" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA030090: AB_10603334, HPA030091: AB_10602593" "unprognostic (8.29e-3)" "unprognostic (3.61e-2)" "unprognostic (7.71e-2)" "unprognostic (8.70e-3)" "unprognostic (2.76e-1)" "unprognostic (6.51e-2)" "unprognostic (1.40e-3)" "unprognostic (5.78e-2)" "unprognostic (1.23e-2)" "prognostic favorable (1.18e-4)" "prognostic favorable (5.09e-4)" "unprognostic (3.66e-3)" "unprognostic (1.20e-3)" "unprognostic (5.31e-3)" "unprognostic (1.14e-1)" "unprognostic (3.76e-1)" "unprognostic (1.20e-3)" 15.7 33.0 17.9 11.7 18.3 10.0 18.2 17.5 18.6 22.4 20.7 21.2 12.6 17.4 18.5 15.5 20.9 9.9 30.3 17.4 17.7 27.5 25.6 17.7 17.5 18.8 18.2 30.9 23.4 21.5 45.2 11.0 18.2 27.8 10.4 22.9 21.3 14.5 54.7 13.1 23.1 10.7 17.2 33.7 20.3 24.7 18.6 15.3 39.1 31.7 14.6 20.2 18.0 18.3 10.7 9.6 20.7 23.0 8.6 13.2 14.8 9.0 15.1 14.9 11.9 7.3 14.0 23.1 13.1 13.5 14.2 5.9 17.5 13.6 8.6 34.5 26.7 22.2 15.7 11.6 17.1 11.2 12.6 16.2 8.5 17.2 16.0 9.1 13.7 23.1 16.6 23.7 13.7 23.5 19.1 13.1 10.2 8.5 9.2 18.1 10.7 21.4 13.5 14.7 32.5 11.9 11.0 13.9 27.3 6.8 20.8 36.1 10.6 10.4 8.9 7.2 13.2 23.8 17.8 21.6 9.0 17.4 28.0 5.2 7.2 6.3 16.8 9.5 13.2 10.9 12.1 12.0 8.2 10.4 12.6 13.2 2.2 10.8 10.9 4.1 10.3 10.3 17.9 18.3 17.5 18.6 17.4 17.7 18.8 18.2 18.2 17.2 18.6 18.3 9.6 16.0 9.6 16.3 19.3 5.7 8.3 10.2 15.9 28.5 14.0 10.2 20.3 8.6 9.7 9.2 50.1 23.7 11.6 13.4 21.5 12.5 20.6 9.2 7.7 10.5 12.1 6.9 19.7 15.5 12.4 10.0 7.7 10.1 12.7 19.5 10.0 8.7 11.3 30.3 22.0 13.9 8.2 7.2 6.9 13.4 11.1 7.6 5.4 21.5 6.1 15.3 16.5 24.1 23.9 7.6 13.1 6.0 16.1 6.8 12.1 12.5 9.2 31.2 19.7 8.8 10.2 21.9 10.4 8.7 6.3 22.7 12.6 14.8 10.1 7.9 ZNF774 MGC75360 ENSG00000196391 "Zinc finger protein 774" Q6NX45 15 90352284-90369146 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.4;Granulosa cells: 45.3;Spermatocytes: 11.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 9.0" "HPA030839, HPA030840" Uncertain Supported "Intermediate filaments,Cytosol" No No "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Intermediate filaments" Cytosol "HPA030839: AB_2673630, HPA030840: AB_10602691" "unprognostic (1.11e-1)" "unprognostic (2.14e-1)" "unprognostic (1.38e-1)" "unprognostic (5.82e-3)" "unprognostic (3.29e-2)" "unprognostic (1.35e-1)" "unprognostic (6.89e-2)" "unprognostic (9.22e-3)" "unprognostic (7.82e-2)" "unprognostic (1.94e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (2.71e-1)" "unprognostic (5.62e-2)" "unprognostic (1.27e-1)" "unprognostic (4.48e-2)" "unprognostic (4.82e-2)" 0.7 2.7 2.3 1.2 4.2 1.0 3.4 4.3 3.6 2.6 0.0 4.6 2.2 2.8 4.1 1.4 3.0 2.9 2.8 1.9 2.6 1.4 1.1 1.1 0.7 0.7 1.0 1.1 3.9 3.1 3.0 0.7 0.8 2.4 7.1 4.0 3.9 5.7 6.2 3.1 2.0 1.8 0.0 0.6 2.6 2.2 2.7 1.5 2.7 7.2 0.9 1.9 1.6 3.3 1.7 0.7 2.1 2.4 0.9 0.5 5.0 1.0 1.7 1.3 1.6 2.7 2.0 0.6 2.0 1.3 3.7 2.5 2.2 3.7 1.3 1.2 4.2 1.8 9.0 1.3 1.6 1.0 1.3 0.5 4.4 1.9 1.8 3.6 2.3 3.4 2.0 0.8 2.1 1.6 1.4 0.9 0.6 4.5 2.5 1.3 1.8 0.5 2.6 4.6 4.8 2.0 2.0 3.1 0.8 2.4 2.1 0.2 1.1 1.4 1.3 1.1 2.2 5.2 3.8 0.4 2.3 2.8 0.7 1.4 0.3 0.7 0.2 0.1 0.1 0.2 0.2 0.3 0.6 0.4 0.2 0.2 1.2 0.7 0.2 0.3 0.1 0.1 2.3 4.2 4.3 3.6 1.9 2.6 0.7 1.0 0.8 0.0 2.7 3.3 0.6 6.4 3.2 0.3 0.7 0.8 2.5 1.0 2.2 6.4 2.4 2.4 4.9 0.0 1.1 0.0 0.0 1.7 0.2 6.8 1.9 2.8 15.4 1.7 2.3 1.0 2.4 0.0 2.5 2.0 1.1 0.9 4.1 3.2 0.0 45.3 0.0 1.5 0.8 8.4 2.3 3.3 0.0 0.3 0.7 11.0 0.3 0.8 0.0 0.0 0.2 2.0 0.0 1.5 1.1 1.7 5.5 2.2 0.7 1.4 1.9 1.1 0.7 5.3 0.0 1.7 1.9 11.8 4.5 1.3 0.3 1.4 0.5 0.3 5.5 2.0 ZNHIT3 "Hit1, TRIP3" ENSG00000273611 "Zinc finger HIT-type containing 3" Q15649 17 36486629-36499310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 222.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060019, HPA078211" Approved Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA060019: AB_2684188, HPA078211: " "unprognostic (5.47e-2)" "unprognostic (1.29e-1)" "unprognostic (8.87e-2)" "unprognostic (1.20e-1)" "unprognostic (3.56e-2)" "unprognostic (1.56e-1)" "unprognostic (4.75e-3)" "unprognostic (6.03e-2)" "unprognostic (6.48e-3)" "unprognostic (2.55e-1)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (2.81e-2)" "unprognostic (1.47e-1)" "unprognostic (2.20e-1)" "unprognostic (1.84e-1)" "unprognostic (6.19e-2)" 27.4 32.4 33.4 17.6 34.9 31.2 32.7 33.6 43.1 26.2 31.3 30.9 24.1 24.6 39.9 30.4 24.0 20.1 27.2 33.9 35.1 35.1 35.9 19.4 39.1 33.5 34.0 31.1 33.1 27.4 24.0 21.0 33.9 26.3 30.5 19.5 26.3 20.0 58.0 30.9 24.1 18.9 35.2 25.5 28.2 50.4 33.4 29.4 28.7 32.4 39.7 30.0 26.5 35.6 39.6 39.0 70.4 55.1 38.6 49.4 38.8 35.8 56.0 53.6 55.2 6.9 55.7 67.3 38.8 18.0 66.8 37.1 25.7 30.8 66.5 35.3 25.7 27.2 41.1 54.3 28.2 73.0 37.7 34.4 69.0 22.1 53.6 60.3 37.1 79.6 48.5 39.8 58.3 36.0 98.3 92.5 50.1 38.0 38.0 33.0 71.2 56.1 67.7 35.2 57.6 42.7 42.7 26.3 73.0 59.5 76.3 72.7 36.4 25.2 42.6 50.9 54.3 41.3 57.6 68.8 54.6 44.3 50.5 15.7 14.5 10.3 15.5 11.3 32.4 22.6 27.1 21.5 20.0 21.6 33.9 27.6 7.9 23.8 26.5 20.0 27.2 17.2 33.4 34.9 33.6 43.1 33.9 35.1 33.5 34.0 33.9 35.2 33.4 35.6 29.0 25.6 27.0 7.5 48.3 46.4 34.1 99.9 38.1 25.4 51.2 75.2 11.8 30.0 47.5 33.1 12.5 93.2 58.1 24.4 88.0 61.1 222.2 37.9 29.9 32.3 43.5 33.9 10.9 51.2 98.5 30.9 21.4 32.3 34.2 48.5 25.4 30.4 67.4 15.2 12.7 33.8 42.7 49.4 36.7 79.1 37.0 34.6 53.4 10.3 66.6 42.5 47.4 12.1 14.7 60.9 36.8 44.4 32.4 47.3 50.6 88.1 33.8 28.3 46.0 36.6 37.5 179.1 71.2 37.2 43.8 77.2 58.3 55.9 44.6 34.0 ZRANB1 TRABID ENSG00000019995 "Zinc finger RANBP2-type containing 1" Q9UGI0 10 124942123-124988189 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029239, HPA029240, HPA029241" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA029239: AB_10599419, HPA029240: AB_10601450, HPA029241: AB_10602205" "unprognostic (2.06e-1)" "unprognostic (5.16e-2)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (1.40e-1)" "unprognostic (9.53e-3)" "unprognostic (4.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (4.20e-1)" "unprognostic (1.46e-1)" "unprognostic (1.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.47e-2)" 13.9 21.1 17.9 6.6 18.7 22.5 13.1 26.7 21.8 14.4 18.8 13.8 5.1 14.4 12.4 10.5 10.8 9.7 18.4 18.1 17.8 10.9 24.8 10.6 8.2 17.7 17.8 19.3 8.8 16.8 8.7 10.6 17.8 11.2 8.8 17.5 9.0 13.6 52.9 15.0 7.7 15.2 18.0 8.7 8.3 19.7 18.3 13.6 10.1 46.4 10.7 10.3 11.7 19.4 15.1 8.6 17.8 13.1 27.1 22.7 7.5 14.5 39.6 27.1 31.3 12.8 11.7 15.7 10.6 18.4 8.8 10.7 22.8 10.7 36.2 16.8 11.3 9.0 9.7 13.8 57.6 13.6 6.6 25.2 30.8 19.9 42.2 37.7 17.3 14.2 1.3 12.7 14.8 12.1 16.2 11.9 6.5 8.2 9.1 13.7 12.7 7.2 12.0 10.9 9.1 15.2 12.3 9.4 16.4 16.7 10.4 11.5 12.9 11.5 11.8 9.7 18.3 13.4 12.5 18.1 13.1 9.5 5.8 0.9 0.4 1.2 0.8 0.1 0.6 0.9 0.9 0.7 0.3 1.3 1.5 1.2 1.7 1.3 0.2 0.5 0.9 0.3 17.9 18.7 26.7 21.8 18.1 17.8 17.7 17.8 17.8 18.0 18.3 19.4 28.6 19.2 25.3 61.7 17.9 24.6 22.8 10.7 22.2 36.9 29.0 21.2 22.9 15.7 17.3 18.4 50.1 12.3 26.3 16.2 0.0 13.1 80.2 29.4 38.6 21.7 26.8 25.7 58.2 11.6 9.8 21.4 14.3 38.5 26.0 34.3 14.6 43.8 12.5 37.0 58.5 19.0 4.1 16.7 22.4 30.3 23.9 24.3 16.0 52.5 13.2 24.2 19.6 56.3 76.0 19.3 11.5 23.0 21.0 31.4 11.9 10.5 19.2 26.0 13.1 34.6 27.6 28.8 19.1 20.5 27.8 27.5 21.4 23.7 13.1 31.1 ZSCAN21 "DKFZp434L134, NY-REN-21, Zipro1, ZNF38" ENSG00000166529 "Zinc finger and SCAN domain containing 21" Q9Y5A6 7 100049774-100065040 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016948, HPA023591" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA016948: , HPA023591: AB_1859037" "unprognostic (2.44e-3)" "unprognostic (3.77e-1)" "unprognostic (2.84e-3)" "unprognostic (1.36e-1)" "unprognostic (4.45e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-1)" "unprognostic (7.42e-3)" "unprognostic (8.59e-3)" "unprognostic (3.76e-2)" "unprognostic (1.67e-3)" "unprognostic (3.10e-2)" "unprognostic (3.13e-3)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (6.09e-2)" 7.8 7.8 10.6 4.5 12.3 6.1 8.0 12.6 11.7 10.3 10.2 11.2 4.6 9.8 9.2 5.7 10.6 6.0 7.6 10.5 10.7 9.6 13.1 6.2 6.2 11.4 11.6 9.9 10.0 7.0 7.6 8.0 11.3 10.8 5.3 9.3 10.3 7.2 14.1 7.0 6.9 7.8 10.6 7.4 9.0 12.2 12.0 7.1 8.3 12.9 4.9 9.4 7.4 14.1 5.9 9.8 16.0 18.7 14.8 9.5 13.1 6.7 10.3 13.0 13.0 7.8 6.7 6.4 8.2 7.9 22.1 5.3 14.5 9.7 12.9 8.5 11.9 5.8 8.6 7.3 16.0 8.4 2.3 11.3 16.8 12.7 21.1 10.8 10.5 13.0 14.0 5.4 9.7 15.1 14.0 13.8 19.9 8.2 7.3 9.5 12.8 7.8 10.8 9.2 8.2 20.9 9.2 19.4 12.9 22.6 7.8 7.0 4.6 11.8 14.6 10.4 9.4 10.7 10.6 14.1 5.5 5.3 16.1 12.9 6.0 12.9 9.9 5.8 10.8 6.6 6.0 9.0 6.3 6.5 6.6 7.5 0.8 10.7 3.9 5.9 7.4 4.9 10.6 12.3 12.6 11.7 10.5 10.7 11.4 11.6 11.3 10.6 12.0 14.1 5.1 3.2 5.1 5.5 4.3 1.5 3.4 4.1 5.2 6.0 3.5 3.6 1.6 2.8 4.4 3.7 2.1 16.6 10.6 2.9 7.9 7.1 2.7 4.0 7.7 4.7 1.8 11.0 3.7 4.0 6.5 5.4 2.6 3.8 2.5 8.0 3.6 5.2 5.2 10.1 4.1 2.5 8.2 2.5 2.1 0.7 5.9 2.9 3.6 7.5 3.0 16.5 3.1 7.1 7.5 4.4 5.0 9.8 3.4 4.0 3.2 11.9 2.5 5.9 0.0 7.7 6.7 14.1 19.7 2.9 3.8 17.6 2.9 8.0 2.8 1.7