Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 ACBD3 "GCP60, GOCAP1, GOLPH1, PAP7" ENSG00000182827 "Acyl-CoA binding domain containing 3" Q9H3P7 1 226144679-226186741 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015594 Approved Supported "Golgi apparatus" NA NA 29000 "Cluster 37: B-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" "HPA015594: AB_1844491" "unprognostic (1.82e-3)" "unprognostic (1.53e-2)" "unprognostic (7.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.85e-1)" "unprognostic (5.34e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.66e-3)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" "unprognostic (1.30e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-3)" "unprognostic (2.54e-3)" 21.6 16.9 11.6 20.4 12.4 25.9 24.4 13.1 13.0 27.6 16.6 23.2 17.5 22.8 20.6 30.8 17.8 23.5 21.4 10.9 13.7 20.2 24.3 22.4 21.3 12.6 13.9 23.2 22.7 28.0 14.6 31.7 12.9 22.8 25.4 16.1 24.1 16.4 21.5 19.3 17.5 21.7 13.1 17.8 31.7 18.8 13.1 18.0 28.8 20.3 25.7 26.9 20.2 13.5 43.7 29.3 24.3 15.1 73.6 65.4 47.2 53.7 55.7 31.5 40.3 38.0 53.2 46.3 48.0 69.7 28.5 33.5 34.6 35.2 43.9 19.4 40.4 22.5 30.3 34.8 47.2 36.5 26.7 48.7 46.0 39.1 51.1 44.7 36.6 22.2 42.6 32.0 51.3 22.1 27.2 28.5 36.1 72.5 38.0 25.0 53.3 47.1 29.4 39.2 27.6 39.8 47.8 52.7 53.0 34.0 54.2 41.5 46.2 31.4 22.0 76.7 51.5 60.4 67.4 57.3 37.3 24.2 52.8 2.1 1.4 1.4 0.9 1.8 1.6 5.0 1.3 0.9 1.0 4.4 1.4 1.3 1.5 1.0 1.5 1.4 1.7 0.7 11.6 12.4 13.1 13.0 10.9 13.7 12.6 13.9 12.9 13.1 13.1 13.5 53.5 67.3 41.5 14.0 50.4 52.0 63.4 17.9 38.7 35.1 50.6 37.2 35.7 27.1 37.9 35.0 56.3 45.3 44.2 46.1 15.6 25.0 24.0 56.6 84.0 47.6 43.5 10.7 29.8 34.7 60.7 55.8 50.4 85.8 24.6 29.8 28.2 52.0 37.9 26.9 31.3 71.9 28.5 25.1 51.0 7.3 40.7 39.4 49.8 20.6 18.0 52.1 18.6 27.6 29.2 39.0 28.4 32.7 87.3 61.7 26.7 32.1 26.9 39.4 32.9 46.6 51.4 72.1 55.8 46.7 77.7 62.4 34.0 33.1 35.6 98.3 ACOT9 "ACATE2, CGI-16, MT-ACT48" ENSG00000123130 "Acyl-CoA thioesterase 9" Q9Y305 X 23701055-23766475 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035533 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 7600 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA035533: AB_10696506" "unprognostic (5.69e-2)" "unprognostic (6.34e-2)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (1.53e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (1.12e-1)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (9.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.15e-3)" "unprognostic (6.53e-2)" "unprognostic (1.68e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" 24.1 18.8 8.0 19.5 7.5 15.8 19.8 7.5 9.5 17.7 10.3 22.0 15.5 22.5 8.4 12.1 17.3 13.6 49.3 7.2 9.1 15.5 14.5 26.1 12.7 8.0 7.5 15.1 14.0 11.7 8.8 17.8 8.6 16.1 16.4 9.6 18.6 22.1 27.6 12.5 15.8 32.3 6.9 18.4 17.7 6.2 8.5 6.3 17.4 14.2 12.5 21.3 14.7 7.5 81.5 54.0 23.1 51.4 37.2 42.0 11.7 62.7 54.3 60.7 58.4 48.5 71.4 4.1 39.1 70.5 81.8 48.3 29.6 79.9 84.2 18.8 44.6 27.4 55.0 35.6 49.9 10.8 33.3 37.5 53.6 71.5 80.5 39.6 90.3 0.6 17.7 26.7 66.7 28.4 15.2 26.1 33.9 31.8 65.3 15.7 87.6 34.4 72.8 29.8 4.5 22.1 68.4 28.3 41.6 85.5 31.9 14.0 84.7 50.7 33.8 73.3 34.7 6.4 16.1 0.5 37.4 10.5 43.6 24.7 30.2 22.2 10.2 43.5 14.1 11.1 12.6 11.3 32.4 9.9 4.0 9.4 15.8 12.3 56.2 5.4 20.8 18.6 8.0 7.5 7.5 9.5 7.2 9.1 8.0 7.5 8.6 6.9 8.5 7.5 34.6 48.1 27.3 12.1 23.0 20.1 45.9 51.8 7.4 5.3 5.6 6.7 44.3 18.6 36.8 16.5 25.0 4.0 21.5 9.7 5.9 59.6 0.8 20.8 22.9 38.7 2.4 11.2 6.1 52.5 11.4 33.4 16.8 21.6 37.3 14.8 32.9 11.8 42.4 5.0 8.6 10.3 16.2 37.1 95.4 0.4 18.0 57.3 33.8 13.1 192.3 11.9 19.6 4.5 3.1 83.4 15.0 25.6 27.7 52.4 14.6 30.3 38.0 9.9 26.3 35.2 65.1 1.6 10.4 3.5 10.7 3.0 21.2 30.4 11.2 38.2 ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 179.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" NA NA 740000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" 34.2 28.0 7.1 28.8 8.2 2.1 21.5 8.5 8.3 34.8 11.4 32.9 24.5 29.7 15.2 29.7 19.3 47.1 32.1 6.0 8.4 34.9 13.5 51.4 9.7 10.2 7.5 16.8 12.7 52.5 7.8 47.4 9.0 34.9 41.7 18.5 54.9 34.8 24.1 16.1 23.0 51.6 9.4 24.0 44.2 11.1 10.6 5.9 39.9 25.0 13.2 56.1 24.3 11.5 188.3 163.6 63.5 32.6 117.2 374.0 67.0 259.6 382.4 191.7 177.9 82.7 147.1 10.1 86.1 247.2 156.7 79.5 30.8 249.7 373.2 6.9 21.5 12.1 102.8 73.0 226.4 8.9 19.1 287.5 139.2 193.3 212.7 341.0 268.9 15.2 21.5 53.2 406.2 25.0 7.2 4.4 8.3 175.2 46.7 3.8 106.3 27.6 299.3 62.4 6.4 11.5 78.4 90.9 57.8 72.9 67.3 12.0 374.2 109.9 97.9 213.9 124.1 12.9 29.5 7.7 175.8 12.0 72.1 0.3 4.0 0.5 0.1 1.3 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 0.5 0.8 0.6 0.3 0.1 0.9 7.1 8.2 8.5 8.3 6.0 8.4 10.2 7.5 9.0 9.4 10.6 11.5 14.4 48.1 37.0 16.0 3.8 35.9 66.6 78.3 26.7 19.3 23.4 9.8 49.7 24.3 82.1 35.0 20.9 24.1 8.9 44.4 3.9 90.2 14.4 42.1 35.3 20.5 10.7 2.5 47.5 115.4 85.1 42.0 80.5 82.1 5.1 26.4 25.0 7.5 125.9 5.0 38.0 32.2 44.7 60.2 44.8 7.8 28.6 54.7 21.4 33.7 21.8 17.5 1.0 30.7 26.7 179.4 30.6 24.8 5.2 108.7 24.9 41.1 51.9 25.1 13.1 31.3 31.9 4.3 2.5 20.2 21.5 34.3 5.6 11.2 32.7 103.8 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 30.6" "Cell type enriched" "Detected in some" 4 "Theca cells: 44.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "HMC-1: 259.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045284: AB_2679285, HPA048453: AB_2680399" "unprognostic (5.94e-3)" "unprognostic (9.94e-3)" "unprognostic (2.76e-2)" "unprognostic (7.09e-2)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (5.88e-4)" "unprognostic (3.34e-3)" "unprognostic (2.89e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (8.86e-2)" 6.6 5.3 0.5 1.8 0.4 0.1 3.8 0.3 0.5 6.0 0.6 4.2 1.1 7.2 0.1 0.9 2.2 2.3 30.6 0.4 0.5 2.2 1.1 6.3 0.9 0.5 0.5 6.1 0.5 0.4 0.8 2.1 0.4 1.8 0.2 0.5 1.3 0.4 1.1 1.8 2.6 1.4 0.2 5.2 2.2 4.1 0.7 0.1 2.1 0.5 0.2 3.0 2.5 0.6 0.0 1.1 16.5 7.5 6.9 8.2 20.9 3.7 1.3 1.0 0.6 0.0 0.1 0.0 4.8 0.4 1.0 0.4 0.4 2.0 0.0 0.3 0.6 2.1 0.5 0.1 6.9 0.0 259.9 3.3 2.0 1.9 1.0 5.3 24.0 0.0 0.3 0.7 5.6 0.0 0.1 4.9 4.7 0.0 1.4 17.3 7.7 0.3 0.5 0.9 0.3 23.9 4.8 0.0 0.6 4.0 3.2 0.4 29.8 9.4 1.0 3.3 0.0 0.1 0.0 0.0 1.6 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.5 0.4 0.5 0.5 0.5 0.4 0.2 0.7 0.6 7.5 0.0 0.0 3.6 0.3 0.4 0.2 0.7 0.0 0.3 0.1 0.5 9.8 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.0 0.1 4.9 0.8 7.5 10.5 0.0 0.0 0.1 0.0 0.3 10.1 0.5 0.9 3.8 7.2 2.9 0.3 0.7 0.0 0.2 0.0 2.0 0.0 0.8 2.7 1.5 0.1 1.8 1.0 0.1 1.3 0.0 9.5 1.4 0.3 0.0 1.9 0.0 0.3 0.0 0.1 0.3 0.1 0.0 3.7 5.0 2.6 2.0 0.2 0.1 0.3 0.5 44.9 0.1 0.3 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADCY6 AC6 ENSG00000174233 "Adenylate cyclase 6" O43306 12 48766194-48789089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018365 Approved Approved "Golgi apparatus" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB018365: AB_2257941" "unprognostic (1.18e-2)" "unprognostic (2.20e-2)" "unprognostic (6.89e-2)" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (3.68e-2)" "prognostic unfavorable (8.23e-4)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-3)" "unprognostic (5.10e-3)" "unprognostic (1.09e-1)" "unprognostic (3.09e-1)" "unprognostic (2.48e-2)" 43.2 15.0 8.9 6.1 7.9 1.3 23.7 5.0 9.2 19.3 10.3 26.3 18.7 20.7 19.0 10.3 17.1 13.9 57.2 8.0 11.2 21.1 9.6 13.5 3.9 5.5 5.4 22.3 22.3 20.7 14.6 14.5 6.6 16.3 20.3 5.7 33.5 16.5 12.1 15.3 21.4 13.6 1.9 4.8 25.1 4.0 14.4 2.8 17.9 12.7 3.2 12.3 12.8 6.4 14.0 25.9 30.2 18.9 32.0 15.9 32.0 16.7 17.1 19.8 13.8 45.7 45.3 0.0 37.2 15.3 8.2 10.9 9.2 11.6 7.9 0.1 13.4 12.5 37.8 8.4 17.6 0.0 10.1 20.0 13.6 17.1 6.5 37.9 18.7 0.8 1.7 4.5 15.6 23.1 0.0 0.5 10.3 21.6 12.3 4.6 11.4 7.7 23.4 41.5 4.5 18.4 17.2 68.0 15.2 13.3 53.3 3.5 21.1 18.3 13.1 9.7 7.4 7.0 3.7 0.4 16.9 0.0 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 7.9 5.0 9.2 8.0 11.2 5.5 5.4 6.6 1.9 14.4 6.4 11.6 0.0 6.4 18.3 0.6 2.7 3.3 7.5 4.0 10.1 22.7 15.0 8.2 7.2 9.8 18.4 20.9 7.4 0.4 38.8 0.0 5.8 0.8 6.8 8.0 8.1 8.4 0.0 17.5 4.0 2.7 7.6 14.3 11.3 1.3 14.6 5.0 7.7 2.5 10.1 18.8 24.9 8.2 0.6 2.8 1.1 11.5 0.7 7.2 7.5 0.6 3.4 0.0 15.1 7.0 9.5 30.3 9.4 0.3 6.3 26.0 2.8 5.8 9.3 19.7 9.5 26.6 1.9 1.7 3.6 2.0 5.1 0.8 13.9 23.7 9.3 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 30.5;Cardiomyocytes: 47.0;Early spermatids: 16.2;Endometrial stromal cells: 50.2;Fibroblasts: 32.7;Late spermatids: 21.4;Leydig cells: 13.7;Microglial cells: 25.3;Peritubular cells: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Cell line enhanced" "Detected in some" "BJ: 4.1;fHDF/TERT166: 4.7;HeLa: 7.6;HHSteC: 4.9;HMC-1: 13.0;U-2 OS: 6.1" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" 26.4 1.9 1.9 1.3 2.0 0.3 10.3 1.2 2.5 20.6 1.0 10.6 1.9 15.4 7.3 6.9 17.7 12.9 62.4 1.4 3.2 3.4 10.3 35.6 0.4 2.0 2.6 17.9 12.0 0.3 6.3 25.7 2.2 15.3 1.8 0.8 2.9 1.0 7.3 7.0 12.1 7.1 2.0 2.3 20.7 7.5 3.6 0.4 11.2 8.5 1.0 40.3 16.3 1.7 0.0 0.7 0.0 2.0 0.0 0.0 0.1 4.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.6 0.0 4.9 0.0 13.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.8 0.0 0.1 0.2 2.1 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.4 6.1 1.5 0.1 0.1 1.7 0.8 0.1 0.0 0.0 0.0 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 1.9 2.0 1.2 2.5 1.4 3.2 2.0 2.6 2.2 2.0 3.6 1.7 2.0 22.4 30.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 47.0 0.0 5.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 16.2 1.3 50.2 3.4 0.0 0.0 1.1 0.4 0.6 32.7 0.5 1.0 1.3 0.3 1.8 3.6 2.3 0.0 1.4 0.0 0.0 1.5 0.0 21.4 13.7 1.5 0.0 25.3 3.5 0.0 0.0 0.0 0.1 0.3 0.0 15.8 0.0 0.0 0.0 0.1 2.2 0.7 6.6 2.2 3.5 4.3 6.5 0.1 0.0 1.0 0.6 0.2 0.1 0.3 AGTR2 "AT2, MRX88" ENSG00000180772 "Angiotensin II receptor type 2" P50052 X 116170744-116174974 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 8.8;lung: 8.8;smooth muscle: 13.2" "Cell type enriched" "Detected in some" 15 "Alveolar cells type 2: 20.4" "Group enriched" "Detected in some" 12 "endometrial cancer: 3.0;lung cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 8 "cerebellum: 2.0" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.13e-1)" "unprognostic (1.71e-1)" "unprognostic (3.22e-2)" "unprognostic (4.37e-2)" 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 5.0 0.0 0.1 0.0 8.8 0.8 0.0 2.6 0.1 1.7 0.0 0.0 0.6 0.0 8.8 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 133.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 81.7;Leydig cells: 425.9;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "ASC diff: 149.9;ASC TERT1: 60.1;HHSteC: 64.9;HSkMC: 147.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" NA NA 380000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" 56.6 45.1 2.0 10.5 2.7 0.9 26.9 2.3 2.7 21.3 1.5 56.7 9.6 69.2 14.0 33.8 59.0 27.9 22.8 2.9 1.9 17.5 23.9 12.6 3.5 2.1 1.5 68.2 21.9 1.1 2.1 133.8 1.4 12.3 27.5 9.6 36.3 9.5 30.3 9.0 26.7 65.5 2.2 10.9 21.6 15.6 1.7 8.6 41.1 57.3 6.9 23.9 17.1 2.3 0.2 0.0 4.0 0.0 149.9 60.1 0.0 0.1 0.0 0.4 0.8 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 64.9 0.0 0.1 147.5 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 2.7 2.3 2.7 2.9 1.9 2.1 1.5 1.4 2.2 1.7 2.3 16.5 0.0 0.0 9.4 1.3 3.7 0.0 0.0 1.2 2.3 0.8 0.5 3.7 41.5 0.0 1.8 6.2 0.6 0.1 0.0 1.9 2.4 1.4 3.3 40.3 4.1 0.0 0.0 14.8 0.4 0.4 81.7 1.1 5.5 0.0 1.6 8.9 1.0 1.4 0.0 14.9 0.0 0.0 0.0 4.6 10.6 425.9 0.8 3.6 8.4 0.0 31.6 0.0 21.6 0.7 0.0 5.0 212.1 0.4 0.1 0.1 0.1 0.7 10.9 39.5 10.0 51.8 0.8 0.6 0.2 3.7 1.4 0.5 2.7 0.0 0.1 ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.4;Endothelial cells: 34.6;Fibroblasts: 99.7;Oligodendrocyte precursor cells: 35.2;Skeletal myocytes: 39.3;Smooth muscle cells: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 140.4;ASC TERT1: 94.9;BJ hTERT+: 205.9;HSkMC: 98.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" 109.5 11.5 6.1 33.5 12.9 0.2 71.2 15.1 8.6 67.7 12.4 76.5 15.1 72.9 13.7 21.7 31.4 67.0 69.2 6.9 9.4 13.4 14.8 22.5 8.1 12.0 12.4 44.2 5.5 4.1 3.4 21.4 11.7 24.7 17.9 0.9 18.0 27.1 57.6 29.2 27.8 63.4 9.9 49.2 28.9 4.4 12.6 4.7 15.7 36.6 8.9 59.4 49.1 15.4 0.0 0.0 17.4 0.0 140.4 94.9 9.4 8.1 205.9 9.2 8.5 0.0 0.0 0.0 7.0 21.4 1.8 0.1 1.7 0.0 4.8 0.1 0.0 0.0 0.1 0.5 30.3 0.1 0.0 98.2 0.0 20.0 0.0 28.7 27.6 2.3 0.0 0.1 6.3 0.0 0.2 4.3 18.4 0.0 1.0 16.5 27.3 1.6 2.2 0.0 9.3 10.1 0.0 0.0 0.0 3.3 0.0 0.0 8.8 35.5 4.5 50.4 0.0 0.0 0.1 0.0 37.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 12.9 15.1 8.6 6.9 9.4 12.0 12.4 11.7 9.9 12.6 15.4 47.4 9.6 2.4 1.0 0.1 14.3 7.0 0.2 3.4 14.4 0.6 6.6 16.6 0.0 0.1 0.0 2.1 1.0 0.5 0.1 0.0 0.2 1.6 1.4 20.2 34.6 0.0 0.0 0.6 0.0 0.8 99.7 1.1 1.0 0.0 2.9 5.0 0.0 1.4 0.0 1.5 0.0 0.0 0.0 17.4 1.5 20.8 0.8 7.2 1.9 0.0 1.9 0.0 35.2 19.2 1.2 0.0 6.4 0.0 1.7 0.0 2.4 1.6 0.8 0.0 39.3 43.5 1.0 0.0 1.4 11.1 2.6 1.7 1.1 0.0 0.6 ANGPTL7 "AngX, CDT6" ENSG00000171819 "Angiopoietin like 7" O43827 1 11189355-11195981 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Cardiomyocytes: 4.1;Enteroendocrine cells: 1.8;Fibroblasts: 6.9;Melanocytes: 3.6;Microglial cells: 1.9" "Cancer enriched" "Detected in some" 14 "melanoma: 18.4" "Region enhanced" "Detected in some" "thalamus: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 65 "SCLC-21H: 41.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 13 "spinal cord: 62.2" "Secreted in other tissues" NA NA 1100000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-2)" "unprognostic (6.95e-2)" "unprognostic (1.22e-1)" "unprognostic (2.67e-3)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.89e-2)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (1.58e-2)" "unprognostic (3.41e-3)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "unprognostic (2.49e-2)" 15.9 2.2 0.3 1.3 0.2 0.0 5.3 1.9 1.0 4.8 0.2 9.2 0.8 0.5 2.1 2.2 2.2 3.8 7.6 0.1 0.4 2.7 0.1 1.3 0.0 0.4 0.5 0.4 0.4 0.0 4.2 0.6 0.3 4.2 1.5 0.2 2.3 6.6 7.8 6.2 1.8 1.9 0.0 0.3 2.3 0.2 4.3 0.3 0.7 5.7 0.2 4.2 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.9 1.0 0.1 0.4 0.4 0.5 0.3 0.0 4.3 0.4 0.1 3.2 0.0 0.3 0.0 0.1 0.1 0.0 1.2 0.1 0.2 0.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.8 0.0 0.3 0.0 0.0 6.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 215.4;HHSteC: 197.9;LHCN-M2: 221.0;U-2197: 176.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 13000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.01e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-2)" "unprognostic (4.87e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-2)" "unprognostic (6.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.34e-6)" "unprognostic (1.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" 60.9 30.0 4.1 35.4 4.1 18.7 18.7 3.6 6.4 52.2 5.0 39.9 23.0 95.4 21.9 24.5 31.2 54.9 31.8 3.6 5.0 17.1 34.4 24.7 16.2 4.7 5.0 75.0 4.6 27.8 1.6 90.0 4.2 110.2 42.7 1.6 10.1 90.3 6.1 6.1 29.6 108.3 5.5 18.3 23.2 8.4 4.0 10.7 4.9 21.7 16.1 53.1 12.0 4.4 15.5 1.9 34.6 6.6 215.4 118.0 3.1 48.3 124.6 17.5 19.9 0.6 11.8 0.0 0.8 76.8 11.4 4.5 4.4 49.7 66.9 2.2 4.2 12.2 1.3 4.8 197.9 51.6 29.5 145.3 15.2 132.7 68.3 150.2 52.6 1.6 27.1 35.8 221.0 0.0 1.1 57.1 5.7 21.7 70.3 2.4 19.8 9.0 12.0 14.4 30.6 41.2 4.9 0.6 8.2 16.3 0.7 11.0 69.8 155.7 9.7 176.7 103.4 3.1 0.0 0.1 78.6 39.4 49.0 72.7 17.5 61.6 12.8 9.5 13.8 23.5 21.4 13.1 32.2 9.4 11.3 5.9 54.4 4.3 18.0 32.2 40.4 14.0 4.1 4.1 3.6 6.4 3.6 5.0 4.7 5.0 4.2 5.5 4.0 4.4 6.4 12.8 10.0 23.5 25.7 7.0 15.5 6.5 4.0 6.9 4.0 2.2 24.9 4.3 10.2 0.0 29.2 18.3 24.9 42.4 3.9 4.2 2.3 7.7 69.3 15.5 18.6 6.3 25.4 6.7 29.0 58.7 4.1 6.1 60.1 8.9 15.0 24.9 17.7 0.0 2.1 15.1 4.1 13.4 28.9 5.3 39.1 28.3 1.8 45.9 53.7 6.9 4.1 19.1 0.8 45.5 28.9 63.9 14.1 13.9 16.9 2.5 4.9 21.4 39.5 32.5 28.5 0.6 2.1 0.9 4.3 6.6 24.4 18.3 13.3 1.6 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Approved Vesicles NA NA 11000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA004689: AB_1078194, HPA008285: AB_1078195" "unprognostic (1.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.05e-3)" "unprognostic (5.19e-2)" "unprognostic (2.48e-2)" "unprognostic (9.07e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.34e-3)" "unprognostic (1.24e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.94e-1)" "unprognostic (4.79e-2)" "unprognostic (4.13e-2)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (9.24e-2)" 84.5 49.2 40.9 38.0 48.3 33.4 61.8 33.4 46.1 71.3 31.2 62.8 25.7 93.7 21.5 75.0 68.4 50.7 112.3 39.1 41.0 41.5 46.2 38.4 30.7 45.7 43.2 46.4 36.5 24.7 36.8 39.0 39.0 64.9 32.6 9.6 46.1 62.6 30.0 65.3 46.7 80.6 38.0 58.4 49.0 15.8 49.8 23.2 44.6 20.5 34.6 107.9 63.4 57.4 23.0 56.7 27.9 39.8 135.4 99.6 32.9 50.3 50.7 45.3 41.2 34.2 29.5 33.1 26.7 102.3 40.7 55.8 22.4 76.0 33.5 23.3 24.6 36.8 27.7 40.4 44.5 31.3 52.3 131.9 46.7 34.5 42.9 46.8 39.1 27.1 24.3 30.3 55.9 82.6 21.2 30.9 72.1 78.5 29.4 25.0 39.9 49.3 42.3 85.2 10.0 31.6 45.8 69.8 19.1 40.1 88.0 35.4 49.1 82.1 25.5 98.7 51.0 32.0 38.2 24.8 77.4 52.0 39.3 27.6 33.0 33.1 26.7 56.9 19.3 14.3 20.8 22.8 32.3 14.7 17.9 20.8 37.3 23.7 72.0 34.1 27.4 24.9 40.9 48.3 33.4 46.1 39.1 41.0 45.7 43.2 39.0 38.0 49.8 57.4 25.2 19.2 18.7 16.6 18.3 8.5 13.4 24.6 10.8 11.9 22.3 24.6 50.2 10.0 18.1 29.5 27.1 25.1 35.2 35.2 3.9 22.2 0.4 17.9 26.9 19.6 19.4 15.3 13.0 27.9 31.0 29.2 31.6 27.6 19.6 21.3 25.7 32.1 30.4 16.8 15.3 36.0 14.2 30.7 8.4 1.7 23.6 19.1 8.8 11.2 28.2 11.0 36.0 23.1 92.3 27.3 19.2 35.3 10.1 11.4 22.4 13.3 10.9 14.2 59.2 28.0 55.9 3.1 3.5 24.7 13.1 16.6 19.9 9.4 21.5 18.7 ARSJ FLJ23548 ENSG00000180801 "Arylsulfatase family member J" Q5FYB0 4 113900284-113979727 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Astrocytes: 44.1;Basal prostatic cells: 60.3;Prostatic glandular cells: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 46.4;HUVEC TERT2: 42.2;LHCN-M2: 42.8;TIME: 53.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036481, HPA036482" Uncertain Enhanced "Actin filaments" "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "HPA036481: AB_2675146, HPA036482: AB_10672356" "unprognostic (1.98e-1)" "unprognostic (1.55e-2)" "unprognostic (4.23e-1)" "unprognostic (5.31e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (6.08e-4)" "unprognostic (2.54e-2)" "unprognostic (2.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (5.31e-2)" "unprognostic (2.20e-1)" "prognostic favorable (2.97e-6)" "unprognostic (2.26e-1)" "unprognostic (8.37e-2)" "unprognostic (1.30e-1)" "unprognostic (2.07e-2)" 1.8 1.3 1.5 1.3 1.1 0.0 1.0 5.0 1.4 4.5 0.2 2.4 0.6 2.0 0.9 3.1 2.8 3.6 2.5 1.2 0.9 2.7 1.7 3.3 0.6 0.9 1.1 2.0 1.1 3.0 0.7 4.3 0.7 3.9 3.3 0.6 5.8 2.2 0.2 0.7 0.7 2.2 0.6 0.2 3.5 0.1 1.9 1.5 0.7 0.6 0.3 3.8 2.1 1.1 2.7 5.3 0.6 0.0 10.1 20.5 0.0 46.4 35.5 29.0 11.3 1.3 3.4 0.0 5.7 22.6 10.3 5.0 0.2 11.7 36.2 0.0 2.1 0.0 4.2 0.0 30.6 0.0 0.0 12.7 11.5 19.7 40.0 20.5 42.2 0.0 0.0 0.0 42.8 0.4 0.0 0.0 1.5 0.0 8.4 0.0 5.1 0.0 38.0 0.0 0.0 1.7 3.1 0.5 2.2 7.5 0.2 0.0 53.6 33.3 8.7 5.0 22.3 0.0 0.0 0.0 16.2 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 5.0 1.4 1.2 0.9 0.9 1.1 0.7 0.6 1.9 1.1 0.7 35.3 9.8 44.1 0.2 2.9 60.3 23.7 15.9 0.2 4.7 2.9 1.3 11.5 10.8 25.8 0.0 0.3 0.1 7.0 0.0 9.2 0.0 6.2 21.1 4.3 23.4 0.0 27.1 0.9 0.2 13.6 4.6 8.2 0.0 0.0 4.2 1.2 0.5 1.7 1.5 17.3 16.2 0.3 1.6 0.3 2.5 0.3 3.6 7.5 0.0 6.8 1.0 3.0 0.5 5.2 5.0 1.5 0.0 49.6 0.1 4.1 4.6 0.2 0.0 8.6 10.5 0.1 0.3 16.9 1.1 0.4 0.6 3.3 4.1 25.6 ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.2;Fibroblasts: 94.6;Microglial cells: 24.4;Sertoli cells: 39.5;Smooth muscle cells: 73.5;Suprabasal keratinocytes: 27.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 16.0;BJ hTERT+: 5.7;HHSteC: 23.2;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" 29.6 7.6 1.2 5.7 1.7 0.1 11.8 2.3 2.0 40.9 0.9 25.5 9.6 69.6 9.7 10.1 16.9 65.9 95.3 1.2 1.2 11.2 41.1 14.3 3.0 1.3 1.2 7.1 13.4 3.8 2.5 4.3 1.6 4.7 11.3 0.2 3.2 11.7 7.8 12.1 17.6 110.5 1.0 2.3 12.0 1.2 1.8 2.5 11.1 19.8 5.5 13.4 5.0 1.7 0.1 0.0 0.0 0.0 1.4 16.0 0.2 2.6 5.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 23.2 0.2 0.0 4.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 1.2 1.7 2.3 2.0 1.2 1.2 1.3 1.2 1.6 1.0 1.8 1.7 12.9 0.0 1.1 0.3 0.1 67.2 0.1 0.0 0.0 0.4 0.4 0.1 8.5 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 4.2 6.8 0.0 0.0 2.0 0.0 0.1 94.6 0.5 0.2 1.3 0.1 13.9 0.4 0.2 0.0 1.7 0.0 0.0 0.0 13.5 0.6 5.9 0.8 14.2 24.4 0.0 0.1 0.0 1.5 1.1 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.7 0.6 39.5 4.3 73.5 0.0 0.1 0.3 27.0 0.0 1.7 0.3 0.0 0.0 ATF3 ENSG00000162772 "Activating transcription factor 3" P18847 1 212565334-212620777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1462.0;Endometrial ciliated cells: 1049.4;Glandular and luminal cells: 1429.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.4;intermediate monocyte: 4.0;myeloid DC: 1.6;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 15 "dendritic cells: 1.6;granulocytes: 6.4;monocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 131.5;HDLM-2: 100.4;SuSa: 155.0" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 9.3" HPA001562 Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA001562: AB_1078233" "unprognostic (2.66e-2)" "unprognostic (1.52e-2)" "unprognostic (2.80e-1)" "unprognostic (4.27e-3)" "unprognostic (3.29e-1)" "unprognostic (1.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" "unprognostic (9.31e-2)" "unprognostic (8.65e-3)" "unprognostic (8.75e-2)" "unprognostic (1.52e-1)" "unprognostic (6.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-2)" "unprognostic (2.08e-2)" 176.1 82.8 14.2 63.3 17.7 45.3 97.6 16.5 18.7 106.2 17.1 66.6 21.0 108.6 9.3 128.4 122.6 135.0 113.7 14.4 20.2 98.1 139.9 116.0 20.8 21.1 16.7 40.2 67.2 48.8 45.0 66.3 17.2 116.3 60.0 16.2 33.1 24.1 30.7 154.9 45.6 313.0 15.4 24.4 104.8 3.9 18.8 84.5 181.1 30.0 3.1 281.2 55.2 25.0 21.1 1.2 40.7 8.7 3.9 10.4 131.5 14.7 11.9 12.5 29.8 27.7 15.5 0.4 6.5 0.9 68.0 11.6 24.6 4.0 20.5 100.4 24.6 1.6 11.6 10.0 72.9 9.0 22.7 18.3 65.3 34.9 80.4 2.4 2.6 23.9 10.0 77.0 1.9 2.8 27.5 5.9 29.2 11.5 9.2 8.1 27.1 18.4 1.8 3.0 18.3 18.4 19.1 34.2 59.0 155.0 19.9 6.5 2.4 3.6 19.5 12.3 6.7 60.4 27.9 7.4 11.9 4.8 10.8 6.4 0.7 0.0 0.3 4.0 0.3 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.2 0.0 6.3 0.8 0.0 0.7 14.2 17.7 16.5 18.7 14.4 20.2 21.1 16.7 17.2 15.4 18.8 25.0 568.2 423.1 146.5 1.6 55.3 202.8 866.2 236.1 1462.0 4.4 753.9 510.9 689.3 92.9 136.0 55.2 0.0 178.9 100.3 611.7 1.9 186.2 3.7 1049.4 318.2 176.2 889.6 2.7 2.6 122.7 330.8 452.6 966.9 1429.3 78.6 5.6 30.7 25.8 103.7 1.7 2.4 758.4 114.0 29.8 282.8 2.8 17.4 351.8 174.3 3.7 32.3 39.9 0.0 1.5 10.8 185.7 484.8 1.2 161.0 457.5 421.3 3.3 133.2 5.3 98.6 279.4 573.7 2.2 3.1 474.6 202.7 420.6 97.1 5.8 349.6 263.6 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626787-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 175.3" "Cell type enhanced" "Detected in many" "Adipocytes: 171.6;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 200.0;BJ hTERT+: 276.4;fHDF/TERT166: 212.8;SuSa: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 58.9 25.0 39.7 25.6 36.3 16.0 16.6 0.0 33.5 47.5 0.3 58.2 12.5 104.5 20.1 32.5 48.4 25.2 59.5 40.2 13.3 9.9 9.3 35.1 12.8 8.0 8.0 40.6 9.9 11.8 3.8 40.6 11.2 33.0 30.2 42.5 7.1 69.7 14.4 54.8 14.4 175.3 0.2 12.2 15.4 27.4 44.7 21.7 15.1 27.7 19.4 37.2 15.3 2.6 45.7 7.8 15.6 15.1 120.4 175.1 84.5 200.0 276.4 32.1 27.4 3.8 22.8 9.8 28.8 212.8 43.5 43.5 22.6 27.7 34.3 126.5 8.0 28.7 37.4 2.5 43.1 42.0 51.3 130.5 26.9 102.9 16.2 81.6 63.5 57.1 12.9 20.3 25.1 2.5 44.3 14.5 9.7 8.7 24.2 22.3 11.6 16.7 11.3 4.0 4.6 6.7 68.3 10.5 30.2 222.1 9.3 21.4 54.9 80.5 11.4 136.6 48.3 13.4 20.9 5.4 80.7 31.0 24.5 3.2 2.0 0.0 8.7 1.3 6.4 0.9 5.4 7.2 2.2 0.3 1.3 3.4 4.0 3.8 2.2 3.7 5.7 2.7 39.7 36.3 0.0 33.5 40.2 13.3 8.0 8.0 11.2 0.2 44.7 2.6 171.6 89.8 68.2 127.6 9.9 97.1 18.9 43.1 41.5 4.8 11.2 9.4 76.5 7.2 35.0 18.4 2.1 27.9 56.2 2.2 0.0 35.3 5.8 78.0 92.4 67.6 23.9 35.9 55.9 14.9 18.9 56.0 13.7 89.7 10.1 30.6 58.9 18.2 38.5 117.8 9.8 2.4 14.2 14.7 38.8 4.8 43.8 20.4 26.6 37.5 18.1 136.1 66.9 199.0 40.4 31.4 11.1 38.0 27.6 48.2 7.2 3.3 39.7 7.8 19.7 50.7 81.2 21.7 2.8 54.7 150.9 26.0 59.7 8.0 3.3 62.0 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 C17orf58 ENSG00000186665 "Chromosome 17 open reading frame 58" Q2M2W7 17 67991099-67996469 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 35.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 55.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 37.3" HPA023036 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA023036: AB_10601144" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (6.66e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (7.65e-3)" "prognostic unfavorable (8.99e-4)" "unprognostic (7.45e-2)" "unprognostic (2.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.22e-2)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.31e-10)" "unprognostic (1.16e-2)" "unprognostic (1.04e-1)" "unprognostic (5.00e-2)" "unprognostic (1.01e-1)" 11.9 5.4 5.2 2.8 5.5 3.9 16.9 5.4 10.0 26.8 4.8 8.4 4.0 15.1 6.9 5.1 7.8 4.7 5.9 5.7 5.3 6.1 9.4 3.4 3.2 5.4 5.3 4.8 4.8 3.2 2.0 35.6 5.1 5.8 7.3 8.9 4.3 3.6 3.5 3.5 4.6 10.9 5.5 2.3 6.8 3.0 5.2 2.1 6.8 7.3 7.1 8.8 7.6 5.5 9.8 9.5 9.3 11.6 6.6 16.6 7.3 4.0 11.4 6.9 11.2 5.6 12.4 13.0 8.9 3.3 12.1 4.9 21.3 8.6 16.6 23.5 21.5 8.4 3.2 17.8 10.4 7.2 14.9 9.2 10.2 6.7 15.4 7.7 32.7 11.2 18.2 19.6 6.7 13.1 1.3 9.5 10.7 23.6 10.0 3.1 10.2 17.4 8.7 6.5 6.9 12.5 6.0 55.5 20.8 11.4 15.8 8.2 6.1 5.8 5.9 4.2 8.5 38.9 30.9 11.6 14.8 12.6 10.5 8.6 2.8 5.0 2.2 2.9 0.7 3.0 0.8 1.7 3.9 0.5 0.3 0.8 1.1 2.7 5.0 0.1 0.4 1.8 5.2 5.5 5.4 10.0 5.7 5.3 5.4 5.3 5.1 5.5 5.2 5.5 21.6 0.0 1.7 6.2 3.5 4.8 5.5 5.6 7.4 8.9 31.0 21.8 4.7 12.8 6.1 11.0 10.4 28.6 4.1 10.5 23.5 10.1 0.9 21.0 40.5 16.3 3.6 8.4 5.0 9.3 21.7 51.6 19.9 19.4 12.7 3.8 14.3 18.5 16.9 5.0 4.6 15.0 10.2 9.7 21.5 2.8 3.7 7.3 8.8 2.8 18.4 31.9 12.3 3.0 4.6 10.7 10.0 5.3 7.0 11.6 10.9 19.7 16.5 15.6 6.6 36.2 14.1 7.3 6.0 20.7 8.4 15.3 4.1 8.3 10.1 7.6 C1QTNF1 "CTRP1, FLJ90694, GIP, ZSIG37" ENSG00000173918 "C1q and TNF related 1" Q9BXJ1 17 79022814-79049788 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 214.2;heart muscle: 319.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 120.0;Sertoli cells: 105.2;Smooth muscle cells: 105.8;Syncytiotrophoblasts: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 313.5;BJ hTERT+: 72.9;HHSteC: 112.3;HSkMC: 61.3;U-87 MG: 66.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025429, HPA051101" Uncertain Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 314000000 40000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB025429: , HPA051101: AB_2681343" "unprognostic (2.58e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (1.20e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" "unprognostic (7.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-2)" "unprognostic (7.48e-2)" "unprognostic (9.81e-3)" "unprognostic (5.83e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (1.95e-2)" 214.2 75.3 9.5 14.8 15.2 0.5 156.0 16.1 13.3 50.2 45.3 38.3 4.6 45.1 6.5 18.9 63.5 24.3 319.1 9.1 18.2 25.3 45.7 44.4 14.0 18.3 25.4 70.5 14.9 13.5 17.5 42.2 18.0 57.1 6.3 0.9 34.9 44.0 27.0 38.6 29.3 13.3 14.1 35.7 25.0 5.4 21.9 5.1 115.0 21.3 6.6 34.7 42.3 13.2 0.1 32.3 0.3 0.1 313.5 27.1 0.2 13.6 72.9 7.0 11.9 2.7 14.0 0.1 1.5 5.1 18.1 0.7 1.0 0.5 5.0 0.1 3.5 0.2 11.7 1.5 112.3 0.1 0.2 61.3 0.2 14.5 0.8 9.3 8.8 1.6 0.1 0.3 1.6 0.1 0.3 0.2 3.0 3.7 27.9 0.1 22.3 0.4 0.0 0.4 1.3 5.3 9.2 1.8 32.7 1.2 0.0 0.0 1.4 32.6 0.8 4.0 4.8 0.3 0.1 0.1 66.2 0.2 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.5 15.2 16.1 13.3 9.1 18.2 18.3 25.4 18.0 14.1 21.9 13.2 36.1 0.0 0.6 4.9 0.4 6.5 0.7 12.3 0.6 0.1 9.2 1.8 10.8 5.7 0.5 1.8 0.0 21.5 0.4 3.2 0.0 19.5 0.1 0.6 17.9 38.3 4.8 2.7 0.2 5.9 1.5 23.6 2.6 0.6 0.0 25.3 120.0 1.9 2.6 0.0 0.9 6.3 2.0 7.5 11.3 0.7 10.5 1.1 3.6 5.6 10.9 0.5 0.0 0.5 0.3 3.7 3.1 3.4 0.1 1.8 0.9 0.2 0.3 0.5 105.2 12.7 105.8 0.0 0.7 0.4 4.5 47.3 0.8 18.1 5.2 0.6 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970786-2697950 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 20.7;heart muscle: 27.1;intestine: 29.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 606.7;Horizontal cells: 301.2;Inhibitory neurons: 476.2;Oligodendrocyte precursor cells: 194.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "HDLM-2: 87.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039796, CAB079031" Enhanced Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB079031: , HPA039796: AB_10673019" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (9.35e-2)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "unprognostic (4.68e-2)" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-5)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-7)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (6.90e-2)" "unprognostic (3.39e-2)" 3.0 0.9 4.5 1.4 0.9 0.0 1.9 0.0 3.0 5.6 0.0 29.9 0.7 20.7 0.5 2.1 4.2 2.3 27.1 2.0 0.5 2.5 0.4 4.6 0.3 0.0 0.5 1.9 0.9 0.1 5.2 2.1 0.0 6.5 1.3 1.7 1.0 3.3 0.9 1.3 5.0 10.2 0.0 3.0 5.4 2.5 1.8 0.2 1.3 0.8 0.3 12.3 3.4 0.1 0.0 0.0 0.1 0.0 3.3 2.0 0.2 3.4 4.1 2.2 1.5 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.8 87.0 0.8 0.1 0.0 0.0 2.1 0.0 0.1 5.1 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 5.4 0.6 5.2 0.0 0.1 0.2 0.0 4.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 4.5 0.9 0.0 3.0 2.0 0.5 0.0 0.5 0.0 0.0 1.8 0.1 2.2 0.0 0.0 96.6 0.2 0.6 1.0 0.0 0.0 20.7 0.8 8.3 48.8 0.0 0.0 0.0 2.1 0.2 1.3 0.6 0.0 0.1 35.6 5.1 14.6 5.2 36.6 0.8 606.7 0.0 0.4 4.2 2.0 0.9 0.0 2.7 2.2 0.1 0.3 301.2 476.2 0.6 0.0 0.0 1.1 90.3 0.9 0.2 0.0 72.1 0.0 6.0 1.0 194.5 21.7 0.4 1.2 4.1 0.2 1.2 0.0 0.1 0.0 1.3 13.1 1.6 26.7 3.4 5.8 0.1 0.1 0.1 1.1 0.2 0.5 3.1 CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 504.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 2467.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006018 Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 21000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA006018: AB_1845934" "unprognostic (7.22e-3)" "unprognostic (1.16e-3)" "unprognostic (3.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.27e-1)" "unprognostic (9.52e-3)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.75e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.30e-11)" "unprognostic (3.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.60e-5)" 115.8 56.6 20.6 137.9 22.7 22.8 66.2 22.8 28.5 133.5 54.7 97.5 37.6 113.6 61.1 60.4 57.1 92.7 236.9 24.5 23.5 45.1 74.2 68.5 38.8 24.1 22.2 54.8 52.6 85.0 28.8 211.8 24.2 113.0 81.3 19.6 67.7 150.1 82.1 29.9 40.0 328.4 22.3 47.5 62.5 39.8 33.2 31.0 77.1 117.1 45.2 160.1 48.2 26.6 257.8 207.4 486.6 152.7 1348.5 1229.5 270.9 1821.7 1378.1 577.5 770.7 238.6 388.3 100.0 351.5 2467.8 850.4 144.9 258.2 318.2 826.5 80.6 138.2 136.6 283.7 295.0 657.1 187.2 254.3 930.5 223.6 868.3 370.6 904.4 537.3 116.4 237.9 172.8 1131.8 141.0 130.2 95.5 305.2 247.0 197.3 122.9 333.3 164.5 243.5 132.7 44.3 238.2 595.4 481.5 753.1 932.2 106.2 145.6 799.8 1706.6 234.2 1350.8 754.6 306.8 385.7 224.8 1478.6 223.6 1857.2 21.7 38.8 23.5 28.3 41.4 27.9 23.7 19.5 22.0 33.4 16.6 17.1 20.0 4.5 26.2 35.7 32.9 23.4 31.2 20.6 22.7 22.8 28.5 24.5 23.5 24.1 22.2 24.2 22.3 33.2 26.6 67.3 22.4 38.5 25.5 29.9 81.3 68.1 82.0 31.3 28.2 51.7 42.7 247.0 25.8 62.7 25.8 18.8 116.8 25.0 14.4 17.6 69.5 11.4 37.5 186.3 104.0 19.7 42.3 37.7 60.5 504.7 198.8 37.2 72.8 59.6 62.6 113.2 54.2 136.9 28.6 47.0 55.9 22.4 58.9 70.7 9.3 100.3 44.6 120.9 27.2 26.3 32.4 21.6 31.2 32.2 71.5 11.4 118.8 140.9 110.6 12.6 17.7 57.2 12.8 59.2 64.9 162.8 27.1 41.9 30.9 76.9 243.0 30.9 69.7 26.1 90.5 CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 858.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported Cytosol NA NA 2800000 "Cluster 39: Non-specific - mRNA processing" "Cluster 46: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA024470: AB_1845925" "unprognostic (2.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.03e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.21e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (6.21e-4)" 118.8 93.9 40.2 64.9 50.0 40.9 92.4 45.3 39.6 110.4 29.4 140.1 46.2 67.7 58.0 134.3 120.5 119.7 71.8 36.9 42.7 115.2 31.2 182.5 35.5 51.9 46.1 83.2 55.1 136.3 28.0 68.3 46.6 47.5 131.4 19.2 151.2 91.2 82.2 41.6 58.5 87.3 43.4 42.5 130.4 26.3 49.1 27.0 80.9 81.6 54.3 85.6 89.3 49.3 419.9 263.7 79.2 54.9 257.6 356.6 79.4 383.9 541.3 267.2 151.1 209.2 323.6 0.4 125.0 417.1 209.1 255.1 86.3 593.1 243.4 109.8 95.2 7.8 124.9 25.6 232.3 21.5 13.9 193.3 187.3 416.6 217.8 472.3 537.1 0.1 123.2 106.8 789.3 8.6 1.0 19.4 45.5 49.7 346.3 35.4 262.4 7.3 454.9 24.3 17.7 94.7 198.1 524.2 122.8 189.7 80.9 98.7 858.1 252.7 212.0 220.6 498.4 32.5 66.8 1.4 625.3 46.2 284.7 7.9 118.6 7.2 106.8 77.9 89.8 34.4 72.6 103.2 163.9 16.6 22.9 62.2 6.1 24.5 73.7 7.4 81.7 136.6 40.2 50.0 45.3 39.6 36.9 42.7 51.9 46.1 46.6 43.4 49.1 49.3 240.0 394.2 134.9 82.9 42.3 47.3 136.6 197.5 38.7 12.0 35.7 32.8 38.4 115.8 264.4 53.3 33.3 24.4 72.4 356.0 181.9 271.4 94.5 70.0 52.7 125.3 24.6 6.9 13.3 195.9 92.0 105.0 103.5 93.3 27.8 47.8 35.7 9.7 38.9 13.5 23.1 104.4 242.1 50.0 239.3 232.8 77.3 86.4 112.1 22.5 66.0 22.6 78.2 48.7 21.6 373.0 191.5 68.8 83.3 237.7 104.1 23.6 288.8 18.0 39.5 85.0 107.9 3.4 3.3 67.5 27.6 8.2 83.5 63.5 98.2 268.2 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 354.3;Granulosa cells: 438.5;Langerhans cells: 255.3;Plasma cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 152.4;HBEC3-KT: 136.6;HDLM-2: 238.8;Karpas-707: 287.9;RH-30: 202.7;RPMI-8226: 114.2" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 20.0 52.6 5.4 8.7 12.9 20.3 13.0 0.0 13.5 26.9 0.0 40.8 17.4 26.1 7.5 12.2 22.1 2.7 51.9 14.4 1.1 9.7 1.9 17.2 5.3 9.6 0.2 14.2 24.5 9.9 23.5 12.9 2.7 20.7 10.4 0.7 10.8 9.1 1.8 12.6 25.9 9.8 7.8 19.7 12.7 4.0 0.0 3.2 20.3 0.0 5.1 26.5 19.9 4.5 0.0 0.0 152.4 0.0 10.1 0.4 0.0 0.0 0.0 0.0 0.0 62.8 0.0 0.0 0.4 0.0 0.0 16.2 0.1 136.6 0.0 238.8 2.5 0.7 0.0 0.0 0.0 57.0 12.6 23.8 2.4 0.0 97.0 0.0 0.0 0.8 17.0 287.9 6.8 0.0 0.0 52.8 50.8 0.0 0.0 0.0 202.7 114.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 89.6 0.0 0.0 4.2 0.0 39.3 0.0 0.0 1.4 60.7 0.0 0.0 32.3 0.0 6.6 0.4 4.7 11.1 0.0 17.1 3.1 16.3 13.8 0.4 1.7 10.4 12.1 1.1 9.4 0.0 1.1 13.6 6.8 5.4 12.9 0.0 13.5 14.4 1.1 9.6 0.2 2.7 7.8 0.0 4.5 23.9 60.9 46.6 10.1 82.9 106.8 23.9 73.4 174.2 7.6 3.4 41.8 354.3 2.8 37.4 12.9 0.0 4.0 128.7 37.5 0.0 3.1 0.8 3.3 110.8 35.7 64.8 37.2 54.1 68.3 2.7 123.6 4.6 3.6 55.8 438.5 19.6 2.2 13.0 3.3 55.2 147.7 12.2 11.9 255.3 3.3 52.5 39.3 39.2 19.7 9.8 170.0 89.6 55.3 4.0 20.7 49.4 124.1 371.2 35.8 34.4 1.4 10.3 6.5 26.3 21.4 112.6 0.8 5.1 50.9 39.6 6.3 122.6 41.5 159.7 8.4 CD151 "PETA-3, RAPH, SFA-1, TSPAN24" ENSG00000177697 "CD151 molecule (Raph blood group)" P48509 11 832887-839831 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen" "Deafness, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 716.2;Exocrine glandular cells: 636.7;Pancreatic endocrine cells: 736.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002428, HPA011906" Supported NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "CAB002428: AB_564129, HPA011906: AB_1846245" "unprognostic (1.50e-1)" "unprognostic (1.12e-2)" "unprognostic (5.47e-2)" "unprognostic (5.45e-3)" "unprognostic (4.10e-3)" "unprognostic (2.45e-2)" "prognostic unfavorable (5.58e-4)" "prognostic unfavorable (9.46e-4)" "unprognostic (5.47e-2)" "unprognostic (2.41e-1)" "unprognostic (1.02e-3)" "unprognostic (3.31e-1)" "unprognostic (4.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.24e-1)" "prognostic favorable (6.92e-4)" "unprognostic (7.83e-2)" 332.4 159.5 54.0 79.7 53.5 25.0 277.8 52.5 67.6 181.6 66.1 219.7 140.6 264.6 103.0 97.5 184.3 132.4 345.8 54.2 65.3 194.3 145.3 240.1 35.4 64.5 57.4 116.2 278.3 85.9 81.1 110.1 60.5 182.9 99.8 9.6 243.5 194.2 113.1 107.0 149.4 255.2 58.3 94.8 187.3 44.8 58.6 15.0 133.5 77.0 30.6 203.1 151.3 58.0 380.0 475.3 71.8 256.3 1088.7 422.8 110.4 587.1 400.4 285.0 241.2 252.6 677.2 0.2 224.0 943.5 388.4 358.4 71.1 498.4 96.1 135.0 236.6 112.8 139.1 193.4 366.7 90.2 157.4 388.6 328.2 164.5 367.8 1089.2 348.8 16.4 135.1 56.3 485.9 196.1 1.9 99.5 48.0 232.9 569.4 20.0 173.7 106.4 642.8 102.1 99.5 111.8 578.9 371.5 121.5 81.6 145.8 102.4 600.0 462.6 209.3 147.5 352.9 62.0 66.5 4.5 437.5 89.7 265.8 24.6 19.1 15.2 5.7 19.3 6.8 3.0 4.7 5.0 11.9 2.0 1.9 3.0 7.3 8.2 24.1 1.8 2.9 10.8 54.0 53.5 52.5 67.6 54.2 65.3 64.5 57.4 60.5 58.3 58.6 58.0 294.4 208.3 79.1 13.1 12.8 70.6 143.2 328.2 60.9 16.6 180.9 203.7 180.0 133.0 159.8 248.3 4.2 222.6 15.6 542.3 19.6 716.2 2.6 60.8 114.6 214.8 127.6 28.6 10.0 636.7 423.8 173.8 236.5 143.7 81.3 103.7 265.2 54.0 130.0 37.0 5.5 388.5 138.4 59.3 70.4 11.3 123.6 81.8 128.1 15.9 75.6 94.8 23.7 3.5 0.7 736.6 477.9 283.2 26.6 307.1 440.6 124.6 52.2 17.0 210.4 96.6 310.3 5.6 13.6 73.4 54.4 185.7 29.7 61.1 289.8 199.6 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" 154.0 58.6 51.8 97.7 70.2 32.3 88.1 61.8 82.7 165.4 39.4 136.3 32.4 201.5 84.6 119.3 103.0 106.5 197.2 50.8 66.5 256.8 72.3 114.6 51.0 73.6 68.0 46.0 49.7 29.3 14.1 120.6 67.0 112.8 66.8 53.1 49.4 152.8 30.7 33.6 54.2 280.4 62.4 43.1 80.0 34.2 88.9 59.6 47.6 53.2 56.4 156.1 73.4 91.4 219.3 25.3 222.7 176.8 299.1 645.6 116.7 561.0 571.4 253.9 304.2 48.3 114.1 129.8 320.1 799.2 77.0 76.8 155.0 151.5 635.7 33.3 64.9 50.0 60.8 88.3 417.3 17.5 6.3 299.3 256.8 363.0 365.1 417.3 427.0 76.0 40.4 138.2 739.0 38.4 34.8 28.5 212.6 50.4 101.8 83.5 247.3 51.5 260.0 58.4 38.9 101.3 144.7 68.4 453.7 228.3 60.0 116.1 601.0 452.2 168.8 199.4 230.1 75.4 111.7 108.6 333.8 151.1 140.5 0.8 5.4 2.5 0.4 4.4 0.0 13.4 0.3 0.2 5.6 11.9 0.1 0.2 1.2 0.0 4.0 1.7 0.0 3.5 51.8 70.2 61.8 82.7 50.8 66.5 73.6 68.0 67.0 62.4 88.9 91.4 178.7 16.0 30.5 24.8 50.8 61.6 50.4 79.8 37.0 3.7 49.9 33.0 172.5 21.5 35.2 14.7 10.4 71.5 2.2 18.1 41.1 39.2 44.9 20.9 103.0 177.1 9.6 40.8 1.5 43.1 211.4 120.5 21.4 53.6 40.0 10.2 88.5 34.4 39.3 1.7 4.2 22.6 20.3 28.2 100.2 27.3 28.6 52.6 129.9 75.9 50.8 13.0 4.1 41.7 196.9 54.7 10.6 87.6 171.2 114.5 0.1 346.1 16.7 26.5 46.0 87.9 162.5 44.0 29.1 29.3 52.0 177.0 8.1 46.5 2.6 49.1 CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.7;Fibroblasts: 95.1;Inhibitory neurons: 31.9;Peritubular cells: 57.9;Skeletal myocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 124.8;BJ: 171.8;BJ hTERT+: 160.3;fHDF/TERT166: 126.6;hTEC/SVTERT24-B: 129.1;hTERT-HME1: 155.6;U-138 MG: 232.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" 63.2 6.5 0.9 14.7 0.8 0.4 24.5 7.8 2.7 20.5 3.6 41.1 7.3 30.3 4.3 10.1 18.4 23.1 12.9 5.3 0.4 6.0 0.4 8.1 7.4 4.2 2.1 9.1 2.0 0.2 1.9 26.3 1.8 7.4 10.6 0.9 5.4 8.5 1.7 6.5 17.3 36.3 2.0 8.1 16.0 2.6 2.1 0.8 2.4 3.4 5.0 16.7 14.0 5.2 3.0 3.3 7.5 15.2 124.8 108.1 45.5 171.8 160.3 23.9 43.8 7.4 0.2 0.0 0.4 126.6 82.4 0.1 0.3 45.5 27.3 0.9 0.3 0.0 7.1 0.1 40.7 0.0 0.1 61.0 30.6 129.1 155.6 59.7 11.7 0.1 0.0 0.4 33.3 0.1 0.0 0.2 17.4 0.0 20.2 0.1 2.5 0.1 12.6 0.0 20.5 50.3 0.0 0.4 0.1 3.2 0.6 0.0 43.3 232.7 2.3 96.0 21.6 0.1 0.0 0.1 63.1 0.0 7.5 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.9 0.8 7.8 2.7 5.3 0.4 4.2 2.1 1.8 2.0 2.1 5.2 2.3 0.0 3.9 2.0 0.2 1.5 0.3 2.4 0.0 3.8 1.2 14.6 5.1 0.0 0.4 0.0 0.0 9.8 0.3 0.1 0.0 1.9 0.7 2.4 75.7 1.4 6.7 0.0 26.5 1.3 20.4 95.1 0.0 1.4 0.0 5.3 2.2 0.0 3.6 1.7 31.9 0.5 0.0 0.0 1.9 0.7 20.8 0.9 0.0 4.7 0.0 0.5 0.0 1.0 3.6 0.9 0.0 57.9 0.6 2.0 0.1 0.1 0.2 1.1 0.0 65.0 8.5 0.1 0.1 0.4 1.0 10.4 1.1 2.2 0.3 0.5 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 18.5" "Cell type enriched" "Detected in some" 28 "granulocytes: 53.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000363, HPA052634" Enhanced Supported "Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 3000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 60: Granulocytes - Receptor signaling" "Cytoplasmic bodies" Cytosol "CAB000363: AB_2083616, HPA052634: AB_2681892" "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 9.0 0.0 0.2 3.7 0.1 0.2 18.5 0.0 0.2 4.6 0.3 8.7 0.6 3.1 4.3 10.2 0.9 7.3 1.6 0.1 0.2 0.2 0.5 1.5 1.8 0.5 0.3 0.1 1.6 0.6 0.2 0.1 0.3 1.0 8.3 0.0 4.7 1.3 0.9 9.0 5.8 2.2 0.3 0.2 1.5 0.9 0.2 3.0 0.4 3.0 2.4 11.1 0.9 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.2 0.1 0.2 0.5 0.3 0.3 0.3 0.2 0.2 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 53.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Cardiomyocytes: 36.9;Extravillous trophoblasts: 75.3;Inhibitory neurons: 63.3;Respiratory ciliated cells: 51.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 23.4;BEWO: 7.6;HSkMC: 24.0;SuSa: 11.1" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" 2.6 1.4 2.6 0.6 3.2 0.0 1.4 3.3 1.9 24.1 11.4 7.8 0.5 12.4 2.8 2.4 7.4 3.8 4.2 2.4 5.6 1.1 1.2 7.6 0.5 2.7 6.3 3.7 1.9 0.6 1.9 28.3 3.1 3.5 2.0 0.0 5.0 10.7 1.3 6.6 1.3 7.9 1.5 0.5 2.7 2.7 4.0 0.7 1.0 6.6 0.5 6.1 6.0 2.7 0.0 3.4 0.2 0.0 1.3 23.4 7.6 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.2 0.1 0.0 24.0 0.9 0.0 0.3 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.2 3.3 1.9 2.4 5.6 2.7 6.3 3.1 1.5 4.0 2.7 6.4 0.0 1.5 66.6 0.0 5.9 2.2 2.8 2.2 0.0 0.3 0.4 36.9 0.0 8.2 0.0 0.0 27.5 0.1 0.0 0.0 0.0 7.4 24.8 10.6 6.6 0.0 0.0 16.0 0.0 75.3 28.2 0.5 1.2 0.0 0.2 2.9 0.0 6.1 0.0 63.3 0.0 16.2 0.3 3.0 1.7 15.2 0.3 5.4 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 12.4 0.0 0.1 0.1 0.1 51.3 0.0 0.0 7.3 15.0 1.2 2.5 1.0 4.1 23.3 0.4 2.1 0.2 1.3 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 CRISPLD2 "DKFZP434B044, LCRISP2, LGL1" ENSG00000103196 "Cysteine rich secretory protein LCCL domain containing 2" Q9H0B8 16 84819985-84920768 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 137.3;Fibroblasts: 185.5;Leydig cells: 271.5;Peritubular cells: 265.9;Skeletal myocytes: 146.2;Smooth muscle cells: 341.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 87.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 87.2" "Cell line enhanced" "Detected in many" "ASC diff: 43.7;BEWO: 69.2;HHSteC: 161.4;HSkMC: 68.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 15.6" "HPA030054, HPA030055" Approved Approved Nucleoplasm,Nucleoli "Secreted to blood" No No 219000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "HPA030054: AB_2732452, HPA030055: AB_10611821" "unprognostic (8.91e-3)" "unprognostic (3.05e-1)" "unprognostic (2.63e-2)" "unprognostic (2.02e-2)" "unprognostic (7.12e-2)" "unprognostic (2.30e-1)" "unprognostic (2.11e-2)" "unprognostic (5.58e-3)" "unprognostic (1.48e-1)" "unprognostic (5.50e-2)" "unprognostic (2.67e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (7.35e-3)" "unprognostic (3.38e-2)" "unprognostic (2.99e-3)" "unprognostic (5.15e-3)" 113.4 29.0 3.3 46.6 4.9 8.1 64.2 3.9 4.6 112.9 2.6 88.9 10.8 115.7 20.3 39.9 129.0 104.0 36.6 3.7 5.2 40.9 17.1 92.7 7.3 5.9 5.5 80.7 23.5 2.5 19.3 122.7 5.9 98.9 18.1 2.4 18.1 27.7 15.0 36.7 58.5 95.0 4.4 24.9 65.9 21.5 4.3 8.2 47.9 12.2 3.7 119.9 69.8 5.7 0.9 2.2 0.6 6.0 43.7 16.2 69.2 34.5 30.4 27.2 19.1 4.7 2.9 0.1 3.0 30.5 8.0 1.0 0.1 0.1 27.3 0.0 0.2 0.5 0.9 0.1 161.4 0.0 0.3 68.0 0.1 8.0 0.1 9.0 0.2 0.0 0.3 0.3 3.1 1.4 0.3 1.7 2.0 4.6 2.0 0.1 0.3 0.4 0.2 5.5 6.7 0.5 8.1 3.5 0.7 9.4 13.7 0.9 3.8 0.4 1.8 28.3 1.0 0.4 0.1 5.8 0.2 0.5 4.1 14.8 20.2 0.7 0.0 1.2 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.0 87.2 0.0 0.0 0.1 0.0 4.2 3.3 4.9 3.9 4.6 3.7 5.2 5.9 5.5 5.9 4.4 4.3 5.7 5.9 3.2 2.3 0.7 0.7 46.1 8.6 0.6 9.6 0.5 3.9 7.6 8.6 2.8 1.6 0.0 0.0 7.4 0.8 1.8 0.0 1.4 12.6 7.0 137.3 21.7 3.0 0.0 2.2 0.5 42.4 185.5 27.0 6.3 7.0 11.5 38.6 0.8 4.7 1.7 1.5 4.1 0.0 36.6 39.6 19.6 271.5 14.8 48.0 9.4 41.5 5.1 3.1 54.3 0.6 0.9 0.3 265.9 0.9 17.1 0.2 0.1 0.9 0.7 92.1 146.2 341.2 1.0 1.9 3.7 42.8 9.0 5.4 5.7 2.2 6.5 CTNNA1 CAP102 ENSG00000044115 "Catenin alpha 1" P35221 5 138610967-138935034 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021089, HPA046119, HPA063535" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 57000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cell Junctions" "CAB021089: AB_10123543, HPA046119: AB_2679547, HPA063535: AB_2685033" "unprognostic (2.25e-3)" "unprognostic (3.32e-2)" "unprognostic (2.82e-3)" "unprognostic (1.80e-1)" "unprognostic (8.40e-2)" "unprognostic (2.35e-1)" "unprognostic (1.66e-3)" "unprognostic (4.83e-2)" "unprognostic (2.28e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.02e-4)" "unprognostic (6.18e-2)" "prognostic favorable (7.34e-7)" "unprognostic (1.54e-1)" "unprognostic (2.31e-1)" "unprognostic (7.62e-2)" "unprognostic (1.04e-1)" 144.4 137.1 88.3 65.9 110.4 33.1 126.4 102.9 100.6 110.9 103.2 155.8 115.5 99.2 115.7 208.9 113.4 95.6 190.7 83.7 91.3 151.8 82.4 134.4 35.6 106.8 99.4 101.5 83.8 120.4 54.3 124.6 105.2 96.3 122.9 54.0 127.7 104.0 87.1 140.6 115.2 115.5 95.9 66.0 125.3 35.0 100.2 33.0 122.9 62.0 69.3 126.8 126.3 139.0 225.3 161.1 237.9 353.6 202.2 220.8 362.0 222.0 277.9 208.1 261.1 337.9 297.4 0.8 182.9 334.3 228.0 167.7 165.9 366.0 240.0 129.6 144.0 94.3 245.7 206.5 243.6 1.7 88.2 140.5 286.0 249.1 269.6 230.6 397.7 66.0 52.9 94.3 227.2 199.4 2.3 28.9 96.2 237.4 3.6 88.8 138.0 135.7 441.9 295.5 94.9 124.8 409.7 568.2 344.3 503.4 201.5 64.4 341.1 217.1 117.4 136.5 156.5 33.8 69.9 13.5 207.0 40.3 286.7 5.1 37.8 3.4 5.8 46.4 3.8 7.9 4.1 4.3 32.3 6.6 0.3 2.1 20.9 0.6 46.8 7.9 11.1 17.8 88.3 110.4 102.9 100.6 83.7 91.3 106.8 99.4 105.2 95.9 100.2 139.0 137.3 259.6 161.0 57.1 19.4 78.5 119.5 134.4 82.0 7.3 74.6 52.3 230.8 87.2 201.8 121.4 20.9 124.8 21.1 320.7 68.4 184.9 17.2 158.0 67.9 141.1 51.0 41.7 37.6 175.5 137.8 97.1 167.1 206.9 40.5 83.3 92.4 66.6 92.8 3.3 31.5 139.0 87.5 80.5 80.9 23.6 77.9 77.9 78.2 104.0 158.5 46.2 6.2 66.4 159.7 328.7 201.4 84.7 24.8 128.7 165.6 140.1 210.1 24.5 98.6 74.9 109.1 18.1 21.0 111.3 77.3 189.9 20.4 44.4 130.6 181.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 CUX1 "CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6" ENSG00000257923 "Cut like homeobox 1" "P39880, Q13948" 7 101815904-102283958 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Transport" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 35.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003277, HPA003317" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Golgi apparatus" "HPA003277: AB_10601804, HPA003317: AB_2666891" "unprognostic (5.86e-2)" "unprognostic (5.39e-3)" "unprognostic (9.62e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (5.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (2.89e-3)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "prognostic favorable (5.72e-7)" "unprognostic (1.12e-1)" "unprognostic (8.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.97e-1)" 30.5 18.0 23.8 24.8 33.6 33.4 17.9 54.0 48.2 35.5 28.0 40.5 33.7 60.9 16.9 32.6 35.3 31.7 82.8 21.5 23.3 40.0 23.2 33.1 19.4 30.8 27.5 46.9 63.3 46.0 24.6 23.1 27.4 30.7 25.3 19.2 36.1 23.2 45.5 24.0 37.3 40.8 26.2 16.9 35.3 9.6 29.3 34.7 49.4 38.8 20.6 32.4 24.8 30.5 41.8 44.0 30.3 37.7 24.1 49.3 18.4 41.1 43.0 17.0 10.9 26.2 26.2 53.6 64.2 40.8 31.3 33.4 19.4 32.9 10.1 25.9 21.8 18.8 32.8 22.2 63.7 24.7 9.9 34.6 65.9 13.1 29.5 48.7 22.3 34.0 44.5 44.2 16.3 85.9 80.8 30.1 12.3 64.0 45.4 52.6 25.1 64.4 27.6 46.5 27.7 82.6 35.8 88.4 35.4 25.1 17.4 29.0 33.5 71.2 47.8 54.4 23.7 28.8 14.5 114.7 65.8 22.3 50.8 3.3 13.9 2.3 3.1 13.4 3.0 2.9 2.3 3.1 10.8 2.4 2.2 3.1 7.0 4.5 35.0 18.2 2.2 8.4 23.8 33.6 54.0 48.2 21.5 23.3 30.8 27.5 27.4 26.2 29.3 30.5 33.7 99.3 60.5 78.4 35.3 26.3 30.9 30.9 33.6 67.2 23.9 17.1 110.5 31.5 40.3 40.5 68.8 54.6 59.6 69.2 9.8 34.4 9.5 50.6 165.2 42.1 42.5 50.0 129.0 24.0 55.5 51.8 62.2 85.0 12.0 97.8 37.5 36.1 32.8 53.8 116.2 48.7 38.7 70.2 42.5 9.4 41.3 75.4 17.8 139.6 65.2 47.7 32.0 96.0 117.5 34.1 50.2 60.9 46.0 55.5 42.9 64.5 37.9 57.3 26.3 105.2 56.6 13.5 14.4 39.9 43.3 88.0 25.7 34.7 46.0 43.8 CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 347.2;Distal tubular cells: 172.1;Fibroblasts: 566.4;Kupffer cells: 191.8;Smooth muscle cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 509.6;BJ hTERT+: 303.5;BJ hTERT+ SV40 Large T+: 294.9;BJ hTERT+ SV40 Large T+ RasG12V: 441.2;fHDF/TERT166: 501.8;HSkMC: 1293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" 366.8 82.6 19.4 143.8 20.2 35.1 237.4 19.1 28.1 268.4 24.5 124.3 53.6 360.7 54.3 138.5 122.1 263.3 190.3 19.4 18.6 124.8 252.8 71.0 215.8 22.3 21.1 112.3 131.2 126.7 21.3 8.5 19.1 47.8 115.5 2.1 116.3 66.2 158.9 99.4 96.5 343.5 19.9 356.6 45.4 19.4 21.0 142.6 103.4 181.3 119.7 107.0 174.3 17.7 0.0 0.0 0.4 0.6 509.6 78.9 0.4 187.7 303.5 294.9 441.2 0.0 0.1 0.2 1.9 501.8 0.0 0.1 0.8 0.2 97.1 187.2 2.4 0.0 0.0 0.0 172.8 0.4 0.9 1293.8 0.0 63.8 0.1 0.0 0.2 0.1 0.1 0.0 1.0 0.4 0.7 0.6 32.2 0.0 0.6 0.8 0.3 224.3 0.2 0.0 0.6 0.6 0.3 0.7 0.0 63.6 272.2 0.4 0.4 0.4 0.5 205.0 0.2 0.2 0.1 0.1 0.6 0.3 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 20.2 19.1 28.1 19.4 18.6 22.3 21.1 19.1 19.9 21.0 17.7 347.2 0.0 1.1 1.3 1.4 76.3 0.3 0.0 9.6 1.5 8.1 14.0 25.0 10.0 0.6 5.5 0.0 0.3 2.1 0.0 172.1 0.8 2.2 1.7 46.8 134.1 0.0 0.0 0.6 20.5 0.3 566.4 1.5 1.0 0.0 0.4 55.6 2.5 2.6 0.0 6.6 3.9 0.0 191.8 110.1 3.7 70.2 27.9 135.2 74.0 0.0 1.9 0.0 12.1 0.1 3.0 0.0 8.6 1.0 1.0 0.1 25.5 0.0 0.8 85.5 43.7 146.1 1.8 5.9 6.3 62.7 0.7 9.6 33.2 0.5 0.5 CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42617840-42649392 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 830.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" 404.4 310.5 147.1 87.4 152.9 82.7 272.2 145.7 189.9 237.3 115.0 192.4 94.8 248.4 58.8 152.4 174.0 139.5 374.3 138.7 163.9 182.9 279.4 201.3 76.3 194.7 174.2 218.3 89.1 62.0 137.4 107.8 169.9 181.4 74.9 27.3 149.8 239.3 203.0 233.6 138.1 200.2 154.8 101.4 182.0 142.7 156.7 54.0 157.8 140.5 72.3 216.7 210.0 160.2 125.5 78.6 126.6 78.6 830.9 654.7 74.4 359.2 330.0 262.2 232.4 104.0 95.6 58.8 156.6 668.8 113.8 112.4 85.3 178.0 133.7 63.9 187.3 83.6 127.3 202.4 211.0 118.4 149.5 397.4 138.1 188.9 124.5 190.8 220.0 74.0 73.5 296.3 361.9 137.9 116.8 108.4 51.0 129.2 142.7 84.9 153.8 131.3 202.0 90.6 56.1 73.2 118.6 113.2 134.0 92.6 90.6 112.0 340.9 282.0 175.3 192.3 137.9 78.3 91.2 72.4 328.8 67.8 237.9 126.3 104.0 300.3 75.9 135.3 76.6 110.1 72.8 83.9 154.0 102.7 50.8 54.0 53.8 63.5 176.7 140.8 95.0 86.4 147.1 152.9 145.7 189.9 138.7 163.9 194.7 174.2 169.9 154.8 156.7 160.2 238.5 86.6 62.2 17.0 51.7 110.1 95.5 184.8 27.3 16.7 52.3 73.2 106.4 105.8 100.9 60.7 4.2 110.0 37.0 90.5 49.0 216.4 4.8 51.4 82.9 161.5 83.7 113.9 12.3 107.0 199.3 183.4 38.2 65.4 62.8 57.8 180.2 230.4 108.3 16.8 16.1 45.8 142.4 50.6 112.0 17.0 253.9 67.7 176.1 25.3 112.5 91.0 33.0 7.1 26.4 156.8 85.6 280.6 36.7 82.3 116.9 110.8 53.3 18.4 190.7 62.5 202.5 23.8 45.5 57.5 112.7 117.9 43.0 233.1 55.2 96.4 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 336.3;urinary bladder: 392.6" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Syncytiotrophoblasts: 24.8;Theca cells: 12.6;Urothelial cells: 30.6" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 141.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 719.8;RT4: 828.1;SK-BR-3: 4047.2;U-2 OS: 1286.3" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria Nucleoplasm "HPA053915: AB_2682307, HPA069551: AB_2686150" "unprognostic (3.07e-1)" "unprognostic (4.91e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (9.97e-2)" "unprognostic (5.03e-3)" "unprognostic (5.62e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-1)" "unprognostic (6.91e-2)" "unprognostic (6.66e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (1.83e-1)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "prognostic favorable (6.45e-4)" 1.2 1.6 0.3 0.1 0.2 0.0 336.3 0.2 0.4 1.9 0.2 0.2 0.0 0.2 0.4 0.1 0.3 0.0 0.0 0.4 1.2 1.6 23.6 0.2 0.0 0.4 1.2 25.5 10.3 2.1 2.5 3.2 1.7 3.3 0.4 0.4 97.7 3.1 0.0 3.4 0.1 0.2 0.3 19.0 4.7 3.4 1.1 0.0 0.1 0.0 0.0 392.6 13.6 0.3 1.2 2.2 0.2 199.9 0.3 0.3 3.1 0.3 0.2 6.4 0.1 14.4 1.1 0.8 1.9 0.3 10.4 2.0 0.7 1.2 1.4 289.5 21.6 2.8 1.0 719.8 0.0 4.3 25.1 1.7 0.2 2.5 1.7 0.0 0.1 0.4 1.8 0.7 1.4 8.0 2.5 0.3 1.1 6.9 31.7 2.6 6.3 2.7 0.0 828.1 3.5 5.0 5.9 4047.2 4.9 0.7 3.9 1.0 0.0 2.4 1286.3 7.7 4.3 2.0 0.6 11.3 1.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.4 0.4 1.2 0.4 1.2 1.7 0.3 1.1 0.3 0.1 0.0 0.0 0.0 0.4 0.0 2.1 0.2 0.0 0.8 7.4 1.3 0.4 0.0 0.0 0.0 0.0 7.9 0.1 0.1 7.9 0.1 5.0 0.1 0.0 0.2 3.5 0.0 0.1 0.2 15.1 3.5 0.0 0.0 0.0 1.4 0.0 4.9 1.7 0.0 0.1 0.2 0.0 0.3 0.8 3.7 0.0 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 4.8 0.2 1.2 0.0 0.3 0.0 0.2 0.0 1.2 6.6 0.0 0.7 0.3 7.4 0.0 0.1 24.8 0.2 12.6 0.7 30.6 DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.9;intestine: 70.4" "Cell type enhanced" "Detected in many" "Club cells: 229.3;Distal enterocytes: 261.2;Early spermatids: 153.2;Paneth cells: 299.9;Respiratory ciliated cells: 155.9;Syncytiotrophoblasts: 267.5;Urothelial cells: 249.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 258.3;eosinophil: 99.2;neutrophil: 77.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 258.3" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 22.8;HUVEC TERT2: 21.5;NB-4: 33.7;THP-1: 98.0;TIME: 49.9;U-2197: 31.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036491, HPA036667" Approved "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" 10.0 0.2 2.2 12.5 2.4 8.5 5.1 3.0 2.6 8.6 1.6 70.4 1.9 1.2 0.9 28.2 1.0 5.7 53.9 2.5 2.3 0.3 3.1 7.1 20.2 4.2 3.2 0.7 0.4 0.2 0.4 2.8 4.3 0.8 46.2 1.2 6.1 0.5 0.3 3.3 5.7 4.2 3.8 7.6 10.8 11.3 3.2 2.2 0.3 0.8 26.8 17.5 10.1 4.5 0.0 0.7 0.0 0.0 2.5 10.2 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 6.5 1.7 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.9 1.0 0.4 0.5 1.3 6.1 22.8 21.5 0.0 1.0 0.0 0.0 0.0 0.1 33.7 0.0 0.3 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 98.0 49.9 0.1 0.2 31.4 0.2 0.1 0.0 0.0 0.8 18.9 0.0 258.3 21.0 99.2 0.0 25.0 0.6 6.5 0.0 0.0 21.6 5.0 0.1 0.0 77.3 0.4 5.1 1.6 0.0 5.9 2.2 2.4 3.0 2.6 2.5 2.3 4.2 3.2 4.3 3.8 3.2 4.5 0.3 0.0 1.3 0.0 1.4 1.7 19.3 72.4 0.0 0.0 0.1 0.4 24.4 0.0 229.3 0.0 0.0 2.5 0.0 261.2 0.0 4.6 153.2 0.5 0.0 0.6 1.8 0.8 0.2 25.3 1.3 1.5 7.7 0.1 91.0 0.0 0.0 0.6 25.0 0.0 0.2 51.6 36.7 10.2 38.8 45.5 1.2 16.6 0.0 19.7 3.5 3.9 0.0 0.0 0.2 68.6 299.9 0.4 6.4 6.5 1.5 0.1 155.9 0.1 6.6 0.2 10.9 1.1 0.6 0.3 1.4 267.5 3.8 0.0 8.2 249.2 DIMT1 "DIMT1L, HSA9761" ENSG00000086189 "DIMT1 rRNA methyltransferase and ribosome maturation factor" Q9UNQ2 5 62347284-62403943 "Enzymes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 104.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042944 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA042944: AB_2678234" "unprognostic (1.58e-1)" "unprognostic (2.27e-1)" "unprognostic (6.02e-3)" "unprognostic (7.16e-2)" "unprognostic (8.95e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (8.88e-2)" "unprognostic (1.18e-2)" "unprognostic (1.62e-1)" "unprognostic (5.31e-2)" "unprognostic (3.70e-1)" "prognostic unfavorable (8.90e-12)" "unprognostic (8.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (5.15e-2)" 16.3 13.6 6.5 13.3 6.5 9.1 19.7 6.7 9.6 17.2 6.4 10.9 8.5 14.6 13.9 17.5 14.5 14.2 17.7 6.6 6.8 10.6 15.4 9.8 15.9 6.7 6.7 15.5 19.3 13.3 10.3 17.3 6.7 15.9 12.0 2.9 15.2 16.2 9.7 8.5 8.8 21.0 6.7 13.3 8.5 8.2 6.6 15.0 13.4 12.8 16.8 26.0 11.4 6.7 33.1 19.9 24.2 44.1 37.7 57.4 35.0 57.3 33.7 57.3 55.8 45.1 36.3 61.4 48.4 61.9 45.4 20.2 38.7 35.8 61.3 46.4 34.0 27.2 15.0 33.8 48.1 32.4 34.7 46.7 31.1 54.1 57.3 28.1 46.1 37.0 49.3 27.9 47.3 43.5 50.1 58.6 36.1 18.9 49.7 28.2 33.3 119.2 45.8 29.9 31.5 19.8 38.5 32.2 35.5 19.6 27.0 29.2 40.3 21.0 29.5 33.7 71.2 27.4 46.7 62.6 27.0 61.6 45.1 7.9 5.3 2.7 6.7 9.1 12.7 10.4 11.2 9.1 9.3 6.1 11.6 9.7 0.1 7.7 6.8 12.1 7.8 6.3 6.5 6.5 6.7 9.6 6.6 6.8 6.7 6.7 6.7 6.7 6.6 6.7 25.3 3.2 9.5 6.5 37.8 50.9 90.3 54.8 69.4 6.2 29.9 20.2 35.3 17.2 36.3 14.7 10.4 45.3 21.9 5.0 21.5 28.6 10.1 23.8 28.3 32.0 4.8 20.4 11.1 22.5 48.1 35.6 13.7 23.2 13.3 13.3 17.5 13.4 33.1 0.0 10.5 12.1 32.6 16.4 22.8 4.4 28.9 18.5 28.4 2.8 19.7 7.4 13.4 8.0 12.9 19.8 7.5 20.3 29.3 104.3 4.0 32.5 24.0 4.7 6.6 51.8 49.8 16.5 20.4 58.7 37.8 35.7 31.1 28.6 18.3 76.6 DISP1 "DISPA, DKFZP434I0428, MGC13130, MGC16796" ENSG00000154309 "Dispatched RND transporter family member 1" Q96F81 1 222815022-223005995 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.7;Gastric mucus-secreting cells: 48.4;Inhibitory neurons: 54.4;Microglial cells: 204.2;Oligodendrocyte precursor cells: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 15.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051411 Uncertain Approved "Nuclear bodies" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear bodies" "HPA051411: AB_2681475" "unprognostic (2.10e-2)" "unprognostic (3.31e-1)" "unprognostic (7.00e-2)" "unprognostic (7.81e-2)" "unprognostic (7.82e-2)" "unprognostic (2.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.27e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-1)" "prognostic favorable (5.00e-4)" "unprognostic (4.13e-1)" "prognostic favorable (3.86e-5)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "prognostic favorable (4.16e-4)" "unprognostic (9.69e-3)" 6.8 5.7 1.7 1.5 2.0 0.2 3.0 4.0 2.5 3.2 3.7 9.0 2.6 4.3 2.0 1.9 2.4 4.6 3.9 1.6 1.9 5.2 2.7 9.2 1.1 1.2 0.9 4.5 2.4 5.1 2.5 4.6 1.1 2.4 2.1 1.3 1.9 2.0 4.1 3.3 3.7 4.2 0.7 2.5 5.3 6.5 1.5 1.4 5.2 3.1 1.4 5.4 2.5 2.6 0.9 2.2 5.6 3.8 10.1 6.1 2.4 3.2 2.7 1.1 1.1 2.6 1.6 0.1 4.2 1.5 2.2 0.6 1.6 1.3 1.6 8.1 2.4 1.1 6.3 1.2 4.4 0.2 1.1 4.8 1.9 2.3 0.9 5.8 2.3 1.2 0.0 0.1 3.9 1.5 1.4 0.3 4.0 6.1 1.3 1.7 15.1 0.2 6.8 0.8 1.6 2.5 1.8 0.7 2.3 2.7 2.7 1.4 4.2 2.3 1.5 3.9 3.6 1.2 0.5 0.3 3.2 0.8 5.1 0.3 0.2 0.0 0.7 0.4 1.6 0.5 0.6 0.7 0.6 0.9 0.6 0.5 0.1 1.0 0.2 0.3 0.5 0.4 1.7 2.0 4.0 2.5 1.6 1.9 1.2 0.9 1.1 0.7 1.5 2.6 4.6 6.4 1.7 42.7 3.6 0.5 0.6 1.2 5.7 2.7 3.4 1.5 7.8 7.2 3.3 11.0 0.0 1.4 2.1 1.0 0.0 1.9 2.1 1.9 3.4 4.9 0.0 0.0 47.7 2.8 1.8 5.6 48.4 4.1 0.0 15.8 6.8 3.3 5.9 0.0 54.4 2.6 4.1 1.6 0.9 3.7 1.5 4.1 0.0 204.2 1.4 0.9 5.2 199.6 15.4 1.3 3.1 3.4 0.7 0.7 6.4 5.8 2.7 2.3 0.0 4.0 3.7 2.1 2.3 5.4 1.1 0.8 1.7 2.8 1.6 0.3 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 239.7;Hepatic stellate cells: 187.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.5;OE19: 45.5;SH-SY5Y: 42.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" 20.7 6.1 3.8 4.3 5.9 0.2 17.1 1.3 6.2 11.0 0.0 22.1 7.9 10.2 0.7 12.1 8.8 4.2 15.5 5.5 4.9 11.2 4.8 23.4 3.2 0.1 0.1 7.2 3.9 3.2 6.3 15.4 0.3 12.5 9.9 3.2 14.0 10.6 6.5 17.2 14.4 5.5 0.1 7.4 15.0 5.4 1.6 3.6 11.9 8.0 3.2 6.5 14.1 4.3 23.3 1.8 76.5 0.1 0.2 0.7 0.3 10.8 5.4 8.2 4.7 19.1 28.7 0.0 11.0 2.5 0.6 28.4 2.9 10.9 8.9 0.0 24.3 0.1 6.0 0.0 1.5 6.9 0.6 3.5 19.0 0.4 16.1 4.1 10.4 0.2 0.1 0.0 9.1 3.3 0.2 0.1 4.7 45.5 5.0 21.9 3.3 0.1 11.9 2.5 5.8 42.7 3.6 1.7 0.1 21.4 1.0 0.2 9.6 16.3 0.0 0.5 23.8 0.4 0.0 0.0 34.5 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 5.9 1.3 6.2 5.5 4.9 0.1 0.1 0.3 0.1 1.6 4.3 239.7 6.4 35.7 38.8 4.4 83.2 52.9 15.4 13.1 10.4 39.8 45.3 8.8 5.7 13.2 25.8 0.0 1.4 8.6 114.6 0.0 6.8 0.4 24.7 69.8 106.5 50.6 0.0 49.3 1.4 3.1 15.4 69.3 42.1 17.8 11.8 187.4 1.3 1.1 6.7 29.7 59.8 26.4 5.8 11.9 1.0 0.3 4.0 32.0 48.7 0.0 89.1 0.0 3.5 13.9 46.3 64.3 0.4 1.0 25.1 15.9 0.2 8.7 3.4 0.0 33.1 22.8 0.7 3.3 41.1 86.0 1.9 7.9 6.4 71.5 72.0 EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975217-69013684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 86.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" 19.4 9.1 7.2 12.8 7.2 5.9 19.5 6.7 10.9 14.0 22.4 25.8 7.4 29.9 9.8 17.5 18.5 17.8 28.5 7.1 7.0 10.2 5.7 28.7 8.2 7.7 7.6 11.6 12.6 5.0 9.3 22.3 8.0 27.9 8.6 8.8 16.4 33.7 20.0 9.7 11.4 25.4 7.8 10.0 15.5 8.9 7.8 11.1 7.9 15.2 8.8 24.7 13.7 7.5 19.0 7.1 12.5 14.4 16.6 32.2 8.6 25.4 31.5 16.0 21.0 9.1 10.2 1.1 3.8 28.1 13.6 6.0 8.3 32.3 19.9 62.3 5.6 20.2 15.5 13.5 18.7 11.5 8.2 26.8 29.4 20.6 25.1 19.4 86.2 0.8 5.9 11.1 53.7 5.5 2.0 3.8 13.5 6.2 3.5 0.8 12.4 8.2 13.9 43.4 1.2 6.3 29.1 1.7 23.5 12.8 6.0 15.9 44.6 40.6 13.4 5.1 24.3 6.0 20.5 9.3 16.3 17.1 23.8 5.4 1.5 0.0 2.0 1.4 2.3 1.1 3.0 4.3 2.4 0.7 2.5 2.7 0.2 2.4 0.5 0.4 6.6 1.3 7.2 7.2 6.7 10.9 7.1 7.0 7.7 7.6 8.0 7.8 7.8 7.5 29.6 12.8 10.3 14.0 3.5 7.1 11.4 13.2 16.5 2.2 7.5 11.7 20.7 4.3 14.5 1.8 16.7 0.9 3.1 5.1 0.0 4.6 16.5 15.3 7.5 23.7 6.0 3.8 11.2 8.2 5.3 9.3 9.2 15.4 0.0 9.4 20.3 3.6 6.7 0.0 21.4 4.5 2.0 6.8 9.8 15.1 3.1 8.6 8.8 30.9 6.5 1.4 1.0 9.5 12.2 12.4 3.4 40.6 5.4 8.3 2.1 1.9 13.2 5.6 0.0 26.8 15.2 5.5 2.5 14.8 4.5 0.8 7.0 6.9 3.4 8.6 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620134-15882329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 317.0;Sertoli cells: 401.0;Smooth muscle cells: 313.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 22.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 253.0;HHSteC: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003897 Approved Approved "Golgi apparatus" NA NA 17000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA003897: AB_1848224" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-2)" "unprognostic (5.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (3.33e-7)" "unprognostic (2.68e-1)" "prognostic favorable (1.45e-7)" "unprognostic (7.47e-3)" "unprognostic (7.20e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.79e-2)" 62.3 13.0 12.9 16.1 17.4 0.6 33.7 15.3 14.0 53.9 14.1 49.7 37.6 46.2 47.1 20.5 20.1 56.0 26.4 11.1 17.2 55.8 37.8 29.0 9.4 18.5 20.1 49.2 15.1 21.6 3.5 53.1 19.7 16.4 53.7 39.8 13.4 39.8 13.8 11.9 42.7 53.7 15.5 11.9 32.0 15.6 16.1 4.8 22.8 24.3 5.2 51.7 21.4 20.8 65.0 38.8 37.7 1.4 253.0 177.6 53.1 73.6 59.8 34.5 46.1 33.3 97.3 0.0 2.4 140.4 114.4 16.4 11.3 9.5 52.4 0.2 12.6 5.7 11.2 34.7 218.1 4.4 0.2 159.8 42.8 91.7 115.7 44.6 17.7 0.2 0.1 0.2 169.0 17.5 0.2 2.8 5.2 50.3 30.8 0.0 109.5 0.8 97.7 92.5 3.1 4.9 21.4 12.4 91.5 6.2 34.2 4.3 28.7 54.7 14.3 32.4 30.7 3.6 0.4 0.1 32.1 10.7 160.0 0.0 2.7 0.2 0.2 10.8 0.1 1.3 0.9 0.4 5.5 0.3 1.1 0.5 4.4 1.0 22.2 0.4 0.1 1.7 12.9 17.4 15.3 14.0 11.1 17.2 18.5 20.1 19.7 15.5 16.1 20.8 121.4 12.8 175.9 91.1 11.6 17.0 39.6 32.0 13.6 9.7 28.7 42.8 27.6 87.2 58.3 23.9 66.7 33.0 15.2 317.0 60.7 69.4 67.6 87.4 72.0 61.4 38.3 0.4 2.2 68.9 7.3 73.4 81.1 152.2 6.3 139.4 36.0 36.0 65.8 6.7 31.1 54.5 67.1 54.1 35.6 49.4 134.8 46.2 35.6 148.0 8.6 15.4 0.0 121.2 96.9 97.0 217.8 43.6 5.2 26.9 69.0 114.6 104.8 153.7 401.0 18.1 313.1 10.9 4.2 22.8 13.1 21.1 11.8 40.0 80.0 97.6 ESYT1 "FAM62A, KIAA0747, MBC2" ENSG00000139641 "Extended synaptotagmin 1" Q9BSJ8 12 56118250-56144674 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016858, HPA076926" Approved Supported "Endoplasmic reticulum" NA NA 720000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA016858: AB_1848404, HPA076926: AB_2686819" "unprognostic (5.02e-2)" "unprognostic (3.62e-2)" "unprognostic (6.26e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (8.44e-2)" "unprognostic (5.41e-2)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (1.77e-1)" "unprognostic (6.85e-3)" "unprognostic (1.29e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.04e-2)" "unprognostic (8.43e-3)" "unprognostic (1.52e-2)" "unprognostic (3.98e-2)" 107.9 39.3 15.2 38.5 14.4 18.7 72.7 18.5 18.9 36.6 19.8 45.9 17.2 53.4 22.2 29.2 47.1 27.8 24.5 13.5 23.0 26.8 46.7 45.0 45.9 34.2 21.7 38.8 39.5 40.7 11.7 38.7 36.2 30.5 36.2 8.9 28.0 47.2 54.2 26.1 30.7 74.4 22.5 37.2 29.3 12.1 23.6 36.6 27.8 33.3 49.8 44.7 32.3 24.0 107.0 78.1 62.2 158.2 90.8 67.3 53.4 117.4 129.3 136.2 94.4 72.4 114.3 40.8 92.2 201.3 50.7 118.7 73.7 120.4 121.6 58.8 54.2 244.7 56.0 58.5 125.9 193.2 371.6 76.7 125.5 147.1 81.3 145.3 117.8 39.2 153.6 263.9 124.4 81.2 70.4 116.4 78.9 44.6 102.5 105.4 85.0 107.3 113.7 89.0 52.4 54.8 174.1 52.9 80.5 71.3 111.1 128.4 154.5 104.8 94.7 59.7 85.7 62.3 99.0 58.7 97.3 79.6 111.7 423.2 37.4 423.0 127.2 69.4 157.2 62.4 129.4 129.5 87.2 48.2 102.3 120.2 9.3 84.2 85.6 29.7 139.6 177.8 15.2 14.4 18.5 18.9 13.5 23.0 34.2 21.7 36.2 22.5 23.6 24.0 44.4 9.6 9.3 4.6 25.9 16.3 19.8 23.5 14.2 5.5 20.5 21.3 8.2 14.3 12.9 31.3 10.4 31.9 22.3 6.1 0.0 36.8 2.0 20.5 15.1 28.2 25.2 17.9 10.2 26.8 18.1 17.6 9.2 19.3 62.7 24.7 27.1 37.8 46.4 0.0 7.1 12.0 22.4 21.3 24.8 2.1 17.4 22.9 35.6 6.5 50.6 5.7 60.8 2.0 4.1 26.2 3.5 25.2 18.5 19.9 2.2 4.4 10.7 5.9 52.6 14.3 22.0 3.9 2.9 18.0 11.9 37.9 40.3 12.5 10.8 12.7 EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095673-44251962 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" NA NA 39000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA078409: AB_2686884" "unprognostic (5.87e-2)" "unprognostic (3.05e-3)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.77e-3)" "unprognostic (2.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.70e-2)" "prognostic unfavorable (5.36e-6)" "unprognostic (7.07e-3)" "unprognostic (2.97e-1)" "unprognostic (3.85e-1)" "unprognostic (1.36e-2)" 33.5 22.8 14.4 22.1 15.4 11.2 29.3 15.4 16.3 36.1 17.5 29.1 26.5 43.1 33.3 20.1 33.7 28.1 27.3 15.6 18.1 26.5 26.9 27.9 16.0 15.5 16.0 33.5 26.5 28.9 20.1 61.9 15.5 29.8 28.7 20.9 26.7 30.2 16.2 25.8 31.0 49.3 14.7 21.6 23.8 21.6 19.4 15.2 27.6 18.4 17.3 29.7 28.5 16.1 57.9 71.6 38.3 121.5 170.4 124.2 60.8 181.1 198.0 93.1 125.1 51.2 36.5 40.4 82.1 188.8 98.5 90.0 41.0 114.0 110.0 83.2 71.5 38.4 33.7 39.7 67.5 37.5 76.6 97.7 73.4 56.3 86.6 108.8 132.7 34.8 50.0 63.9 68.4 40.3 25.9 22.3 43.8 67.1 70.9 32.3 116.1 21.1 53.9 49.1 30.9 35.5 118.1 41.4 28.1 67.0 69.8 37.2 137.8 127.4 90.6 133.1 111.4 33.4 46.0 30.4 84.7 27.9 140.0 15.2 17.5 19.4 20.9 17.7 23.5 9.0 16.5 19.3 21.3 8.8 15.4 15.2 3.4 26.3 12.8 7.4 14.2 15.5 14.4 15.4 15.4 16.3 15.6 18.1 15.5 16.0 15.5 14.7 19.4 16.1 24.5 16.0 10.6 41.4 8.7 15.2 17.3 22.0 10.8 11.5 11.0 11.4 10.2 8.6 13.5 12.9 14.6 34.3 10.6 21.1 5.9 33.5 43.2 7.9 17.1 19.2 1.8 6.7 64.3 23.7 37.0 32.3 7.7 11.5 6.3 22.7 22.9 18.3 18.3 13.5 63.3 12.9 12.2 10.8 7.2 23.0 27.4 10.4 5.4 28.1 10.2 17.4 7.2 50.3 51.8 24.0 14.9 28.6 7.0 23.6 31.6 8.2 8.1 15.0 19.7 15.8 20.7 51.2 24.4 10.2 12.6 35.3 9.2 12.2 15.0 15.3 FAM114A1 Noxp20 ENSG00000197712 "Family with sequence similarity 114 member A1" Q8IWE2 4 38867677-38945739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.6;granulocytes: 2.4;monocytes: 3.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 204.7;BJ hTERT+: 244.1;fHDF/TERT166: 273.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067948, HPA069104, HPA069701" Uncertain Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 96000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" Nucleoplasm "HPA067948: AB_2685931, HPA069104: AB_2686087, HPA069701: AB_2686175" "unprognostic (2.13e-3)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (4.66e-2)" "unprognostic (9.40e-3)" "unprognostic (6.77e-2)" "unprognostic (2.54e-1)" "unprognostic (2.31e-2)" "unprognostic (4.88e-2)" "unprognostic (1.55e-1)" "unprognostic (3.06e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.63e-6)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (3.44e-3)" 28.4 48.1 7.9 23.6 11.8 2.0 20.2 7.8 9.2 48.4 23.7 34.6 22.9 29.2 17.8 35.1 19.5 36.4 23.7 9.9 11.4 11.8 54.2 21.2 8.9 13.7 12.5 41.5 25.6 22.4 18.5 35.6 11.2 35.5 33.7 3.1 61.2 27.8 16.6 15.6 24.4 61.7 9.0 8.8 34.4 12.5 12.1 4.3 17.6 22.7 19.5 35.6 26.4 13.4 43.5 30.7 18.5 21.9 197.4 204.7 6.1 167.9 244.1 69.7 105.8 8.1 33.0 0.0 23.0 273.8 118.8 11.9 0.1 53.7 80.1 0.2 4.6 3.1 30.3 40.6 70.6 0.1 5.8 122.1 17.0 101.2 23.3 157.2 101.4 0.1 3.4 0.2 102.9 11.0 0.1 2.3 3.8 18.3 15.6 0.8 90.9 3.2 23.4 8.7 0.7 9.4 33.8 0.7 33.8 42.8 20.8 3.8 156.3 75.4 34.8 95.3 39.5 0.7 0.2 0.3 123.3 3.3 63.0 0.6 3.2 0.0 0.1 3.6 0.0 0.4 0.1 0.1 2.6 0.1 0.1 0.1 2.4 0.0 1.4 0.3 0.0 0.9 7.9 11.8 7.8 9.2 9.9 11.4 13.7 12.5 11.2 9.0 12.1 13.4 28.1 16.0 13.2 5.9 2.2 12.2 47.4 43.7 15.4 0.3 29.9 21.2 17.2 14.3 56.0 7.3 0.0 2.2 0.2 46.8 9.8 45.6 1.0 17.5 88.6 35.2 15.7 3.6 1.0 61.0 47.0 94.9 35.7 39.1 1.3 30.4 31.1 68.3 16.1 0.0 1.8 78.7 83.4 7.2 15.0 6.3 110.9 8.7 21.4 17.8 6.4 12.2 0.0 14.6 31.0 47.6 41.6 116.2 8.5 92.6 39.0 11.7 47.8 1.2 19.7 49.4 44.3 1.2 5.5 23.6 10.2 3.4 3.1 94.1 32.0 82.7 FAM122A "C9orf42, MGC17347" ENSG00000187866 "Family with sequence similarity 122A" Q96E09 9 68780065-68785566 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056646 Approved Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" Nucleoplasm "HPA056646: AB_2683202" "unprognostic (1.88e-2)" "unprognostic (7.62e-2)" "unprognostic (9.17e-2)" "unprognostic (1.48e-2)" "unprognostic (2.55e-2)" "unprognostic (1.16e-1)" "unprognostic (9.79e-2)" "unprognostic (1.45e-2)" "unprognostic (4.18e-1)" "unprognostic (8.49e-3)" "unprognostic (1.45e-2)" "unprognostic (4.58e-3)" "prognostic favorable (1.34e-5)" "unprognostic (9.35e-2)" "unprognostic (3.02e-2)" "unprognostic (2.72e-1)" "unprognostic (6.89e-2)" 9.9 9.3 4.6 5.8 4.9 5.3 9.7 8.2 6.3 9.7 15.0 7.9 4.4 9.3 6.7 8.3 8.5 5.6 9.0 5.4 5.4 9.7 9.9 6.8 7.4 5.1 5.4 10.5 8.9 11.0 6.8 10.2 5.1 7.7 6.5 6.8 8.2 8.4 8.9 7.6 7.4 7.8 4.4 8.3 7.4 4.9 5.0 6.5 8.5 8.6 7.2 7.2 8.0 5.0 5.2 3.4 4.8 4.1 15.9 10.3 6.4 7.3 6.9 6.3 5.0 1.2 2.5 11.0 3.5 7.7 4.5 9.6 5.3 4.9 7.8 11.9 5.6 6.1 6.0 4.4 9.7 11.2 4.1 8.4 11.0 5.8 4.5 7.1 6.3 7.8 6.5 12.1 6.8 2.9 6.3 2.9 6.0 12.4 6.2 7.6 6.6 3.4 5.7 4.3 7.6 3.4 5.4 4.5 3.8 6.6 2.7 4.8 8.0 5.8 4.2 11.0 5.5 14.2 6.1 4.4 6.3 6.9 6.7 1.9 2.0 1.5 1.7 1.9 1.4 1.5 1.7 1.8 2.2 2.5 3.5 2.0 1.1 1.8 1.9 2.6 2.0 1.0 4.6 4.9 8.2 6.3 5.4 5.4 5.1 5.4 5.1 4.4 5.0 5.0 10.0 3.2 9.8 0.0 19.6 23.6 18.7 13.3 20.5 18.8 18.2 17.0 15.9 10.0 13.1 5.5 16.7 28.2 11.8 11.3 66.5 18.3 32.0 10.4 20.2 17.2 18.0 27.0 0.0 13.8 17.0 13.9 14.3 8.1 17.7 12.7 17.2 18.6 21.6 8.4 0.0 17.0 10.2 22.3 17.0 15.4 15.2 15.0 14.2 0.0 16.8 38.3 24.7 0.0 0.0 12.9 15.8 17.0 18.3 11.9 11.1 27.2 23.0 19.8 46.0 18.8 43.9 52.4 21.3 19.5 23.7 30.6 16.8 23.1 15.3 17.8 FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Cardiomyocytes: 6.6;Fibroblasts: 19.7;Hepatic stellate cells: 4.6;Langerhans cells: 9.5;Melanocytes: 7.2;Suprabasal keratinocytes: 4.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2197: 259.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" 3.1 2.7 0.0 0.5 0.1 0.1 3.4 0.1 0.3 2.6 4.2 1.8 0.8 4.7 0.4 4.0 2.0 16.1 15.9 0.3 0.0 4.1 10.2 2.5 0.1 0.0 0.0 7.9 1.3 0.2 0.1 0.2 0.0 0.6 2.0 0.0 1.2 0.2 0.3 3.4 1.3 4.7 0.0 0.6 1.0 0.4 0.0 0.2 2.7 1.3 0.5 4.4 1.3 0.1 0.0 0.1 0.0 0.0 27.8 28.4 0.0 14.9 56.2 0.3 0.2 0.0 0.0 0.0 0.0 57.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.6 0.0 35.6 4.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 57.1 0.0 259.7 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.8 6.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.8 0.0 0.0 0.3 0.0 0.0 19.7 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 0.0 2.8 0.1 7.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 1.8 0.0 0.0 0.1 4.8 0.7 0.2 0.0 0.0 0.0 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FERMT2 "KIND2, mig-2, PLEKHC1, UNC112B" ENSG00000073712 "Fermitin family member 2" Q96AC1 14 52857268-52952435 "Predicted intracellular proteins" "Cell adhesion, Cell shape, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040505, HPA072965" Uncertain Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 230000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA040505: AB_10673300, HPA072965: " "unprognostic (4.38e-2)" "unprognostic (4.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.42e-2)" "unprognostic (2.51e-2)" "unprognostic (4.89e-3)" "unprognostic (2.50e-2)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.58e-1)" "unprognostic (1.99e-1)" "unprognostic (3.87e-2)" "unprognostic (3.96e-3)" "unprognostic (7.69e-2)" "unprognostic (3.14e-1)" "unprognostic (1.73e-3)" 148.4 21.2 28.7 38.8 31.6 0.5 57.6 29.0 37.3 44.7 18.0 104.3 13.1 105.1 26.3 46.8 55.7 65.7 66.9 31.0 27.4 55.4 108.3 47.9 15.3 35.7 29.1 43.6 20.6 18.4 13.1 116.5 33.5 69.1 33.3 29.5 22.6 117.9 48.8 13.4 29.3 155.6 30.6 37.6 46.4 15.5 27.6 6.9 35.9 69.6 6.6 77.7 29.1 38.1 22.8 18.9 101.6 46.8 163.7 133.7 84.6 148.4 95.2 172.3 107.9 34.1 17.6 0.1 49.4 153.1 33.8 9.6 80.1 11.1 128.3 0.2 22.6 31.9 83.1 40.3 209.6 0.4 12.6 129.4 23.5 95.3 125.4 78.5 91.2 16.8 0.6 153.4 131.7 28.0 7.7 0.5 64.3 0.2 51.3 3.9 103.8 0.4 60.9 20.6 6.2 130.5 157.8 35.0 37.7 103.3 30.1 1.1 115.2 134.5 92.4 108.2 56.0 22.6 29.4 0.6 30.9 0.2 33.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 31.6 29.0 37.3 31.0 27.4 35.7 29.1 33.5 30.6 27.6 38.1 152.7 76.9 42.0 116.5 1.0 18.6 150.6 15.5 13.6 39.5 33.8 41.4 65.8 24.3 25.6 40.5 37.5 74.8 2.3 0.2 31.3 48.5 68.2 20.1 141.7 110.4 0.0 2.7 13.7 33.2 178.1 103.9 3.6 40.2 58.3 31.6 110.3 82.3 10.4 15.2 16.1 0.5 4.1 8.9 19.5 27.9 74.9 4.4 46.2 29.0 4.8 52.3 1.0 41.2 92.0 27.6 0.1 174.9 4.5 40.0 0.0 44.7 10.1 56.0 151.2 83.4 174.1 4.1 16.2 2.2 8.1 102.6 7.9 12.3 0.4 37.0 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.7;Fibroblasts: 52.5;Intestinal goblet cells: 80.2;Leydig cells: 28.0;Peritubular cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.6;CACO-2: 38.6;HHSteC: 11.8;HSkMC: 22.1;OE19: 45.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 71.7" "Secreted to extracellular matrix" NA NA 2600000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (9.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.17e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-1)" "unprognostic (5.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (9.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (2.67e-4)" 122.7 13.6 1.3 31.1 2.3 0.1 64.4 1.5 3.9 100.1 9.0 39.4 49.6 105.8 17.2 19.1 85.8 123.6 149.0 1.0 1.5 24.3 11.0 60.2 28.6 2.4 0.9 125.1 33.1 28.0 21.7 81.2 1.5 58.4 62.1 9.9 49.6 49.2 12.6 25.9 21.2 106.5 2.1 18.2 135.6 6.3 1.5 9.6 71.3 25.6 33.8 45.4 60.0 1.4 0.0 0.1 0.0 0.0 10.6 0.7 0.2 7.1 8.1 0.0 1.1 38.6 0.0 0.0 0.8 7.7 0.0 0.3 0.0 0.6 0.5 0.0 0.0 0.0 0.9 0.0 11.8 0.0 0.0 22.1 0.1 0.0 0.4 5.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.3 0.0 45.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 1.0 0.3 2.0 0.0 0.3 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.3 1.5 3.9 1.0 1.5 2.4 0.9 1.5 2.1 1.5 1.4 9.3 0.0 6.3 0.0 0.0 6.9 5.0 1.5 6.2 0.2 10.3 26.7 1.6 2.8 2.1 7.3 0.0 1.1 0.4 2.9 0.0 1.9 0.1 1.1 12.1 8.3 6.1 0.0 0.1 0.7 0.7 52.5 12.8 1.6 0.0 0.5 19.2 0.1 1.2 0.0 0.0 80.2 0.0 0.3 9.3 0.4 28.0 0.6 12.4 7.5 0.6 11.9 0.0 0.0 0.0 1.5 2.2 28.6 0.0 11.7 0.7 0.2 0.7 1.0 6.6 1.3 15.5 0.0 0.3 0.6 4.3 3.1 1.2 2.0 8.6 1.6 FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.1;Fibroblasts: 521.9;Leydig cells: 327.4;Peritubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 1782.4;BJ: 2156.3;fHDF/TERT166: 2692.9;HBF TERT88: 1741.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" 432.4 134.3 20.5 116.3 18.1 2.2 166.1 22.8 22.7 279.9 83.0 156.4 37.1 157.5 50.8 126.1 150.6 257.0 242.7 20.6 22.8 45.4 35.7 120.7 50.3 28.5 44.6 90.3 37.3 35.5 25.7 442.0 23.1 188.3 90.4 29.8 59.3 184.4 31.8 64.2 69.1 409.6 22.7 63.1 68.6 33.5 22.7 24.2 78.8 89.8 38.8 260.4 104.3 20.6 81.0 21.2 222.9 91.8 1304.4 1782.4 1.3 2156.3 1208.9 1374.5 1211.0 0.1 178.5 0.8 178.8 2692.9 112.8 20.5 68.6 270.0 1741.5 1.1 32.5 0.4 159.8 0.3 286.0 1.2 0.9 1362.7 8.5 884.5 192.7 612.1 811.6 11.2 0.5 0.3 227.6 0.5 22.6 2.0 181.3 0.4 181.9 0.7 92.7 1.0 150.4 1.7 39.2 93.5 764.6 13.6 76.5 462.6 23.5 6.2 986.8 507.4 479.8 268.0 323.8 1.0 1.1 2.3 177.4 0.9 67.0 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 2.6 20.5 18.1 22.8 22.7 20.6 22.8 28.5 44.6 23.1 22.7 22.7 20.6 76.9 64.1 9.4 56.5 1.1 64.1 31.9 36.4 10.2 2.3 25.6 24.6 127.5 8.6 42.5 23.9 0.0 114.4 2.5 0.9 0.0 62.6 2.3 44.4 176.7 111.4 3.0 3.6 9.6 5.8 352.1 521.9 3.1 23.0 1.3 66.5 142.5 17.4 20.6 1.7 16.2 0.2 8.2 10.8 91.6 9.8 327.4 11.5 110.3 30.0 9.9 116.1 0.0 9.5 0.9 117.8 0.7 270.8 0.9 108.4 0.0 5.5 74.9 4.3 59.2 62.5 129.3 1.5 4.4 2.2 48.2 54.7 7.1 47.5 0.9 65.3 FYB2 "ARAP, C1orf168, FLJ43208, RP4-758N20.2" ENSG00000187889 "FYN binding protein 2" Q5VWT5 1 56718789-56819696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.5;fallopian tube: 13.7;liver: 17.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.4;Collecting duct cells: 31.3;Endometrial ciliated cells: 11.1;Glandular and luminal cells: 10.8;Respiratory ciliated cells: 48.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "T-47d: 5.1" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in some" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (6.12e-5)" "unprognostic (1.78e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (9.19e-3)" "unprognostic (4.77e-3)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (3.71e-1)" "unprognostic (2.86e-4)" "unprognostic (3.84e-2)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.04e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 3.6 14.5 0.2 0.3 0.9 0.3 0.2 13.7 0.0 1.5 1.0 0.1 3.5 17.1 2.0 0.0 0.0 0.0 0.1 1.0 6.3 0.8 0.0 0.0 1.5 0.4 0.0 2.1 1.7 1.5 0.0 0.6 0.0 0.0 0.0 0.4 1.3 0.1 2.5 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 22.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 6.3 0.0 0.0 6.8 31.3 0.0 0.5 0.0 0.0 3.9 0.5 0.0 11.1 0.7 0.0 0.0 0.0 0.0 1.5 0.0 7.3 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 48.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 GCOM1 "FLJ30973, GRINL1A, MYZAP-POLR2M" ENSG00000137878 "GRINL1A complex locus 1" 15 57591908-57714745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Cardiomyocytes: 3.9;Gastric mucus-secreting cells: 4.1;Granulosa cells: 5.7;Paneth cells: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.4;naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 49.0;RT4: 19.1;TIME: 20.4" "HPA039827, HPA068141" Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA039827: AB_10673364, HPA068141: AB_2685962" "unprognostic (1.10e-1)" "unprognostic (3.62e-4)" "unprognostic (1.10e-1)" "unprognostic (5.43e-3)" "unprognostic (1.31e-3)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (7.69e-4)" "unprognostic (1.22e-1)" "unprognostic (3.22e-3)" "unprognostic (3.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.61e-1)" "unprognostic (4.03e-2)" "unprognostic (7.44e-2)" "unprognostic (1.67e-1)" "unprognostic (5.78e-2)" 5.2 9.1 0.4 2.0 0.7 3.0 2.4 3.9 0.3 1.8 0.0 3.8 5.9 3.1 0.1 14.8 0.8 2.1 20.1 0.2 1.7 1.5 0.6 7.0 2.0 3.3 0.7 2.3 9.1 0.4 0.0 10.3 3.5 2.9 3.6 0.9 3.7 2.4 6.4 5.7 7.2 2.5 0.0 3.4 7.0 2.1 1.2 0.5 0.7 1.1 4.7 9.9 0.6 0.2 6.3 1.3 0.1 5.8 0.3 0.0 1.4 0.8 5.1 1.6 1.7 4.0 5.6 0.0 0.7 0.0 5.0 3.4 0.0 4.2 1.6 0.0 0.2 49.0 1.4 0.2 0.0 0.1 0.1 0.2 2.2 0.4 11.7 0.2 6.3 0.1 2.4 0.1 0.3 1.1 0.0 0.0 0.1 12.0 0.6 0.0 10.7 0.0 0.0 19.1 0.0 1.9 1.2 2.7 0.0 0.7 5.3 0.2 20.4 0.4 3.1 0.4 0.3 0.2 0.0 0.0 3.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.2 1.4 1.4 0.0 0.1 0.0 0.7 0.0 0.1 2.1 0.4 0.7 3.9 0.3 0.2 1.7 3.3 0.7 3.5 0.0 1.2 0.2 2.7 3.2 0.5 0.3 0.4 0.0 0.3 0.0 1.8 0.0 0.5 0.3 3.9 0.0 0.6 0.0 0.0 0.1 0.0 1.7 0.0 1.8 0.2 0.4 1.0 1.8 0.0 0.0 0.2 1.1 0.1 0.2 4.1 1.4 0.0 5.7 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 1.1 0.4 0.0 0.3 1.8 0.0 0.7 0.0 0.0 0.5 0.0 1.6 4.8 1.5 0.0 0.4 1.4 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.1 0.6 0.1 0.1 0.0 1.1 0.5 0.9 GJC1 "CX45, GJA7" ENSG00000182963 "Gap junction protein gamma 1" P36383 17 44798448-44830816 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.0" "Group enriched" "Detected in many" 4 "Sertoli cells: 157.8;Smooth muscle cells: 101.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071788 Uncertain "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Cell Junctions, Cytosol" "HPA071788: " "unprognostic (1.84e-2)" "unprognostic (2.04e-1)" "unprognostic (2.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (7.02e-2)" "unprognostic (4.01e-1)" "unprognostic (1.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.02e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.55e-8)" "unprognostic (5.18e-2)" "unprognostic (2.20e-1)" "unprognostic (8.52e-2)" "prognostic unfavorable (7.83e-4)" 9.5 0.7 3.1 3.6 2.8 0.8 5.2 10.1 3.8 9.2 5.5 28.6 1.6 24.7 2.9 2.7 5.3 5.4 11.8 2.3 1.4 2.2 0.7 7.2 2.7 2.1 2.9 2.2 1.4 3.4 0.6 40.0 2.6 8.9 2.9 1.0 1.1 18.6 4.6 2.0 5.3 32.7 1.3 0.7 7.6 8.8 4.0 1.6 6.7 5.9 2.0 11.4 6.1 3.0 44.5 21.9 62.0 18.9 8.3 10.6 20.5 50.3 36.6 50.0 52.6 12.4 24.7 0.5 2.3 46.4 69.9 10.1 29.2 13.7 70.8 0.5 19.8 0.4 12.1 1.6 3.8 0.3 1.7 8.8 1.6 37.0 11.8 20.4 17.1 9.6 1.8 0.5 31.4 0.4 6.7 4.3 29.5 0.1 16.2 39.5 73.8 0.3 11.4 16.8 10.2 21.5 4.6 0.5 16.2 41.3 10.9 8.0 12.3 43.8 39.3 22.2 38.9 0.4 11.3 32.5 15.9 0.3 40.7 2.0 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.2 0.2 0.2 1.0 0.5 0.1 0.2 0.1 0.1 3.1 2.8 10.1 3.8 2.3 1.4 2.1 2.9 2.6 1.3 4.0 3.0 11.7 0.0 0.0 0.7 0.2 2.0 1.7 0.5 0.0 3.4 0.6 1.4 25.1 0.0 0.2 1.8 2.1 0.5 0.4 0.1 0.0 1.5 1.5 1.4 14.9 19.5 0.0 0.0 8.1 0.0 2.6 6.3 0.0 3.0 0.0 9.4 4.2 0.3 1.5 13.5 1.4 0.0 0.0 0.3 4.2 0.3 1.5 1.2 3.6 1.0 0.6 0.2 0.0 0.0 0.3 0.6 0.0 2.2 0.0 1.4 0.0 0.3 0.2 0.9 157.8 4.8 101.1 15.6 28.4 0.6 3.0 0.5 0.8 7.8 0.1 1.3 GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "Astrocytes: 301.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 47.1;WM-115: 34.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005534 Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Nucleoli, Vesicles" "HPA005534: AB_1078973" "unprognostic (2.53e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (8.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.35e-3)" "unprognostic (2.24e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-1)" "unprognostic (3.54e-2)" "unprognostic (1.48e-5)" "unprognostic (9.13e-3)" "unprognostic (5.41e-2)" "unprognostic (3.21e-3)" "unprognostic (7.00e-2)" 6.1 1.9 9.2 3.6 8.8 0.1 8.9 1.0 5.4 7.2 0.0 11.6 1.2 11.8 2.7 3.7 8.2 3.8 1.6 6.3 5.5 1.7 0.3 3.4 0.9 1.7 10.4 13.2 0.7 0.5 1.1 11.9 3.0 5.5 2.9 1.8 2.8 8.2 1.1 8.3 3.4 10.7 0.5 1.1 2.6 1.7 14.4 3.0 4.6 2.3 1.7 4.8 7.3 2.3 0.0 0.0 47.1 0.4 16.9 23.6 3.5 3.1 9.0 9.3 12.8 0.0 0.0 0.0 1.7 22.1 22.7 10.1 8.7 8.9 10.8 0.0 7.0 0.0 6.0 0.0 9.0 0.0 0.1 21.0 12.9 10.6 6.8 5.7 10.6 5.4 0.0 0.2 5.6 5.6 0.4 0.0 20.9 0.0 21.2 12.4 0.1 1.4 0.2 6.4 1.5 0.0 6.3 7.0 4.1 23.8 8.0 0.1 11.3 13.6 18.8 16.0 6.0 0.1 0.0 0.0 7.3 0.2 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 8.8 1.0 5.4 6.3 5.5 1.7 10.4 3.0 0.5 14.4 2.3 2.9 0.0 7.7 301.3 0.2 23.5 7.2 8.5 31.9 1.6 20.5 27.1 1.8 0.0 2.3 1.8 0.0 21.1 0.5 0.0 0.0 0.0 16.6 2.4 12.6 3.4 0.0 0.0 0.8 0.0 13.6 25.9 0.0 4.6 1.3 10.5 3.9 0.0 3.3 0.0 3.6 0.1 6.1 0.3 6.3 5.4 19.3 0.4 8.8 22.5 0.0 13.6 0.0 8.5 0.7 0.1 0.0 3.4 1.2 6.6 0.0 3.8 1.5 1.1 13.1 17.0 12.1 0.3 2.2 7.9 15.5 34.2 0.7 5.2 0.1 5.0 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666726-155737059 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 38.4;Alveolar cells type 2: 56.1;Breast glandular cells: 37.4;Breast myoepithelial cells: 24.9;Distal tubular cells: 19.6;Ductal cells: 21.8;Smooth muscle cells: 49.4" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.2;non-classical monocyte: 10.1;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 35 "dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.2" "Cell line enhanced" "Detected in some" "HAP1: 6.8;HEK 293: 5.5;Karpas-707: 9.7;MOLT-4: 18.5;RPTEC TERT1: 12.1;RT4: 14.2;SH-SY5Y: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 7100 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB010887: AB_259901, HPA056004: AB_2683007, HPA058617: AB_2732624" "unprognostic (4.81e-3)" "unprognostic (2.60e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (1.99e-2)" "unprognostic (7.77e-3)" "unprognostic (1.07e-1)" "prognostic favorable (2.38e-4)" "unprognostic (1.85e-3)" "unprognostic (6.46e-2)" "unprognostic (3.42e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" 14.4 7.8 10.1 17.0 24.1 1.2 15.4 2.8 14.0 14.5 0.1 27.1 8.7 16.1 6.2 7.5 9.5 12.6 33.7 12.7 8.0 15.6 8.0 21.0 8.5 5.3 10.0 5.6 13.1 31.4 3.9 25.9 4.5 25.8 10.3 17.0 5.3 13.9 5.1 2.5 9.2 28.9 8.7 14.1 8.6 1.2 10.2 7.5 7.2 18.7 9.2 7.3 6.6 8.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 6.8 0.0 0.0 0.0 5.5 1.3 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 3.6 0.0 9.7 0.0 0.0 18.5 0.0 0.0 0.0 0.2 4.1 0.0 3.0 12.1 14.2 2.5 8.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.2 0.0 2.3 0.1 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.1 8.2 10.1 11.5 0.0 1.0 10.1 24.1 2.8 14.0 12.7 8.0 5.3 10.0 4.5 8.7 10.2 8.5 38.4 9.6 56.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 37.4 24.9 0.0 0.0 6.8 11.0 0.0 0.4 1.7 0.0 19.6 21.8 0.0 5.5 9.7 10.9 0.0 0.0 0.0 2.0 0.3 8.3 0.0 15.2 3.8 3.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 12.9 2.2 0.0 0.0 0.0 49.4 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 HEYL "bHLHb33, HESR3, HEY3" ENSG00000163909 "Hes related family bHLH transcription factor with YRPW motif like" Q9NQ87 1 39623435-39639643 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 69.5" "Cell type enhanced" "Detected in many" "Late spermatids: 17.5;Leydig cells: 26.1;Peritubular cells: 56.8;Sertoli cells: 52.6;Skeletal myocytes: 33.4;Smooth muscle cells: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 8.0;LHCN-M2: 20.8;RH-30: 26.5;THP-1: 6.2;U-266/84: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001438, HPA076960" Approved Approved Mitochondria,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA001438: AB_1079052, HPA076960: AB_2732326" "unprognostic (1.98e-2)" "unprognostic (7.92e-2)" "unprognostic (4.19e-3)" "unprognostic (3.49e-1)" "unprognostic (2.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (7.20e-2)" "unprognostic (5.92e-2)" "unprognostic (1.19e-2)" "unprognostic (2.35e-1)" "unprognostic (8.50e-2)" "prognostic unfavorable (2.26e-6)" "prognostic unfavorable (3.57e-4)" "unprognostic (2.67e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.63e-5)" 17.9 12.4 9.5 5.6 12.0 0.1 9.3 10.5 6.9 18.5 4.1 7.2 1.9 27.9 5.7 4.8 17.4 8.0 57.0 5.4 15.0 9.5 4.2 23.5 1.7 11.3 15.6 13.4 69.5 2.4 15.3 29.5 12.9 17.0 3.4 6.7 2.7 14.4 6.0 2.9 4.9 25.0 7.3 6.3 6.0 16.0 17.1 1.3 20.4 5.4 2.0 8.7 11.3 8.3 0.0 2.8 4.8 0.0 0.0 0.5 0.3 0.0 0.1 0.0 0.1 2.0 0.3 0.0 1.6 0.5 0.0 0.0 2.8 0.0 0.3 0.0 3.2 5.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 8.0 0.5 0.7 20.8 1.9 0.0 0.1 0.0 0.2 0.1 1.4 26.5 0.2 0.0 0.5 0.6 0.0 0.0 0.1 0.0 1.1 0.0 6.2 0.0 0.0 0.2 0.0 0.0 0.7 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 12.0 10.5 6.9 5.4 15.0 11.3 15.6 12.9 7.3 17.1 8.3 1.3 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.9 0.1 0.0 3.6 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 1.0 5.4 1.3 4.0 1.9 0.0 0.0 0.1 3.5 0.3 13.3 2.0 2.4 0.0 0.7 1.4 0.0 0.3 1.7 0.2 0.2 0.0 0.0 2.3 17.5 26.1 0.4 5.4 4.7 0.1 0.4 0.0 0.0 2.4 2.8 0.3 56.8 0.0 0.2 0.0 0.1 0.0 3.9 52.6 33.4 29.5 0.4 2.0 0.1 0.1 0.3 0.3 1.9 0.4 0.2 HRCT1 "LGLL338, PRO537, UNQ338" ENSG00000196196 "Histidine rich carboxyl terminus 1" Q6UXD1 9 35906202-35907136 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.4;breast: 24.9" "Cell type enhanced" "Detected in many" "Adipocytes: 72.4;Distal enterocytes: 232.3;Intestinal goblet cells: 57.8;Paneth cells: 316.5;Proximal enterocytes: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 18.0;HBEC3-KT: 10.3;HeLa: 15.9;Hep G2: 11.7;U-2197: 27.0;U-251 MG: 13.1" "Low region specificity" "Detected in some" HPA067038 Approved Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA067038: AB_2685767" "unprognostic (2.48e-2)" "unprognostic (4.88e-2)" "unprognostic (2.43e-2)" "unprognostic (2.49e-1)" "unprognostic (5.69e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.63e-2)" "unprognostic (2.53e-2)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-1)" "unprognostic (2.00e-1)" "unprognostic (9.41e-2)" "unprognostic (2.80e-1)" "unprognostic (9.43e-2)" 29.4 1.8 3.9 1.8 4.0 0.0 24.9 3.3 4.9 4.1 2.7 20.6 8.9 6.0 1.0 1.8 5.5 0.3 9.7 3.7 3.3 7.4 1.6 4.8 0.6 3.9 3.6 2.7 1.3 0.5 1.1 2.9 3.9 4.6 11.8 1.1 6.7 2.7 5.4 6.4 11.0 1.8 3.6 0.8 3.6 2.4 3.8 0.1 4.9 3.8 0.2 7.4 4.4 3.2 0.4 0.2 0.0 0.2 0.8 5.9 0.0 0.2 0.5 0.1 0.0 0.2 1.7 0.0 18.0 0.4 3.4 0.0 0.0 10.3 0.0 0.0 0.0 0.0 15.9 11.7 2.3 0.0 0.0 5.8 5.2 2.0 1.2 0.8 6.3 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 4.8 2.4 0.0 0.3 0.1 3.4 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.2 5.3 0.2 5.3 27.0 13.1 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 3.3 4.9 3.7 3.3 3.9 3.6 3.9 3.6 3.8 3.2 72.4 6.4 1.5 0.3 0.3 2.2 0.4 0.4 0.6 2.0 2.4 11.0 1.2 4.3 2.1 0.0 0.0 23.3 0.5 232.3 1.9 1.9 0.1 2.1 0.4 40.8 1.2 0.0 0.4 0.2 6.2 7.4 0.0 0.8 0.0 1.0 50.7 0.6 1.8 0.0 0.2 57.8 0.0 0.9 2.0 0.5 10.8 0.4 1.8 0.0 0.0 10.8 0.0 0.0 0.1 4.6 316.5 9.4 0.0 0.8 64.6 13.0 0.9 2.5 13.1 3.5 4.7 0.1 0.2 0.1 1.8 2.6 0.6 0.3 24.0 0.4 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 158.8;Leydig cells: 43.5;Peritubular cells: 42.9;Skeletal myocytes: 99.0;Theca cells: 25.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 182.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" 68.0 6.0 0.9 8.7 1.3 13.4 50.4 0.9 1.3 35.4 5.0 33.9 8.7 42.4 10.6 15.1 26.2 35.5 194.9 0.9 1.0 6.2 3.2 38.0 1.2 1.0 1.0 93.0 6.8 0.4 15.7 20.4 1.0 26.3 4.8 0.1 22.8 6.7 32.1 28.1 16.9 11.8 1.0 2.9 21.9 4.3 1.7 2.2 26.0 12.9 0.7 62.4 32.6 0.7 0.0 1.0 1.4 0.0 5.8 10.8 0.3 2.4 0.2 2.8 0.6 0.1 0.1 0.0 13.6 6.4 1.4 0.1 1.2 0.0 0.9 0.0 2.3 1.3 13.9 0.0 6.1 0.0 0.6 1.2 0.0 4.2 0.0 1.7 9.8 0.0 0.3 0.0 10.2 0.0 0.2 36.5 6.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 15.8 0.3 26.4 0.5 0.2 28.8 0.1 1.1 8.1 1.4 4.7 182.1 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.3 0.9 1.3 0.9 1.0 1.0 1.0 1.0 1.0 1.7 0.7 12.6 0.0 0.0 0.0 0.0 5.2 0.5 0.0 0.6 0.0 0.5 0.9 16.5 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 1.2 0.3 8.1 5.3 0.0 0.0 0.0 0.0 4.2 158.8 0.5 0.3 0.0 6.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 8.6 1.4 43.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.4 0.4 0.0 0.1 0.0 0.0 0.0 99.0 10.6 0.4 0.7 0.6 5.3 1.4 0.9 25.2 0.0 0.2 IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 120.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 141.8;Fibroblasts: 87.5;Hepatic stellate cells: 499.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 53.6;U-2197: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: AB_1845820" "prognostic favorable (4.42e-4)" "unprognostic (8.36e-2)" "unprognostic (5.67e-3)" "unprognostic (7.67e-3)" "unprognostic (4.27e-1)" "unprognostic (1.63e-1)" "unprognostic (2.59e-3)" "unprognostic (2.66e-3)" "unprognostic (3.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.58e-3)" "unprognostic (4.70e-3)" "unprognostic (4.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.85e-3)" 38.7 16.7 9.2 44.6 9.3 0.2 27.2 7.0 12.1 56.2 6.4 24.8 8.8 50.0 15.9 24.5 25.9 33.4 40.9 8.5 10.8 5.0 36.7 53.0 47.1 7.8 8.3 5.0 3.4 3.7 5.7 61.1 7.1 30.0 19.4 2.0 18.9 31.5 6.1 44.0 15.6 50.8 8.3 20.5 33.6 5.8 10.8 13.1 12.6 13.8 43.0 120.7 21.2 8.6 0.0 0.0 0.0 0.0 0.3 1.4 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.1 16.9 0.3 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.7 0.3 0.4 53.6 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 162.9 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 9.3 7.0 12.1 8.5 10.8 7.8 8.3 7.1 8.3 10.8 8.6 63.5 6.4 7.2 39.5 1.0 24.2 17.0 73.9 27.3 0.0 9.4 4.1 5.8 4.3 77.8 0.0 0.0 0.0 0.1 2.2 0.0 3.0 0.5 12.4 7.1 141.8 10.7 8.0 0.2 7.9 0.0 87.5 48.4 20.6 1.3 0.0 499.4 5.0 0.1 0.0 0.1 0.2 2.0 20.8 10.2 1.6 20.5 1.7 1.8 1.0 0.0 9.5 0.0 0.5 0.1 12.1 0.2 12.4 0.2 5.2 0.0 0.0 62.1 0.1 0.0 65.5 11.5 0.0 0.4 3.3 48.4 0.1 1.2 0.1 1.1 4.9 ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.0;Hepatic stellate cells: 54.3;Inhibitory neurons: 61.0;Leydig cells: 41.3;Microglial cells: 53.4;Oligodendrocyte precursor cells: 93.5;Peritubular cells: 74.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.1;HEL: 8.1;SH-SY5Y: 11.8;SuSa: 16.9;WM-115: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 500000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" 8.8 15.5 1.9 4.5 1.8 8.5 5.9 0.0 6.2 21.8 3.6 9.6 6.3 10.6 4.0 15.5 5.4 9.4 20.1 7.8 0.7 4.0 14.8 8.9 4.1 0.9 1.3 5.0 1.8 2.6 1.7 9.8 0.4 12.5 6.8 0.7 4.2 10.8 2.8 3.0 9.1 15.8 0.7 22.6 7.5 6.9 5.0 1.8 20.7 9.8 2.4 6.5 4.5 1.2 0.2 0.0 4.3 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 10.1 0.0 3.2 1.4 0.0 0.1 0.2 3.8 0.0 0.0 0.1 0.6 8.1 0.1 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.4 0.3 0.0 0.2 0.5 11.8 0.1 0.5 0.7 16.9 0.0 3.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.0 6.2 7.8 0.7 0.9 1.3 0.4 0.7 5.0 1.2 20.8 0.0 14.7 16.0 0.1 2.5 1.1 0.1 1.2 1.2 1.1 2.9 12.9 2.8 3.1 1.8 0.0 0.2 0.0 0.0 0.0 0.1 1.5 1.4 4.9 21.6 0.0 3.0 82.0 0.0 0.5 7.5 0.0 0.9 6.3 36.2 54.3 1.3 2.8 0.0 61.0 0.1 0.0 31.9 2.2 4.2 41.3 5.7 3.6 53.4 0.1 0.6 0.0 93.5 6.2 0.0 0.0 74.9 0.4 0.2 0.0 0.1 0.0 0.0 0.0 3.2 3.3 0.6 0.9 0.0 1.7 0.3 1.8 25.9 0.4 0.3 ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1206.9;Pancreatic endocrine cells: 1393.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 2711.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" 491.9 179.3 61.5 241.5 78.2 81.5 216.2 75.0 90.9 259.2 68.3 265.3 147.4 330.4 171.7 168.6 172.0 347.4 390.3 60.2 74.3 180.4 287.1 233.6 118.0 88.4 80.6 157.1 135.3 145.4 59.8 459.5 88.9 248.1 223.6 27.7 130.7 427.7 157.9 92.2 150.8 710.0 76.6 204.7 160.1 91.2 86.4 77.5 161.5 194.5 106.2 357.4 119.1 88.9 638.0 907.0 495.4 559.6 1183.4 1019.5 398.1 2063.9 1239.6 999.0 903.9 215.9 1478.2 164.5 354.1 1830.9 638.0 438.9 149.1 1204.1 1122.0 163.1 112.7 195.8 416.3 253.6 826.4 48.3 195.5 1027.7 658.2 1040.8 426.0 2711.1 1263.6 81.0 136.6 76.5 1700.8 109.0 80.1 46.7 107.4 200.6 428.2 52.0 357.0 30.9 1454.8 186.2 108.0 271.4 649.9 114.6 498.2 813.7 153.9 175.0 1362.6 1280.0 712.2 904.2 719.7 64.7 14.8 91.2 956.6 198.2 518.5 7.5 35.1 16.1 83.4 69.8 22.8 109.6 191.8 138.7 33.9 40.3 24.9 68.4 9.0 90.3 108.2 11.4 266.8 117.2 61.5 78.2 75.0 90.9 60.2 74.3 88.4 80.6 88.9 76.6 86.4 88.9 631.5 342.9 143.8 26.4 118.0 546.7 435.5 531.6 208.3 32.8 147.1 307.5 210.8 241.6 268.1 226.2 31.3 210.3 217.8 179.8 13.7 1206.9 6.6 194.6 437.9 421.1 193.3 153.0 37.2 411.3 515.2 374.7 95.8 406.5 88.7 561.8 375.9 268.1 179.8 38.7 52.4 97.4 213.6 170.1 206.7 18.3 254.5 217.8 343.3 67.5 119.4 72.0 111.2 42.7 66.8 1393.7 128.5 601.8 181.2 412.5 75.6 68.7 171.5 45.5 637.7 236.3 724.0 10.1 76.0 84.4 170.5 219.7 211.3 225.6 127.0 296.1 KCNE4 MiRP3 ENSG00000152049 "Potassium voltage-gated channel subfamily E regulatory subunit 4" Q8WWG9 2 223051814-223198399 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 37.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 32.3;Melanocytes: 32.0;Sertoli cells: 118.3;Smooth muscle cells: 128.3" "Cancer enhanced" "Detected in all" "breast cancer: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "AN3-CA: 164.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011420 Approved Approved "Nuclear bodies,Microtubules" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Microtubules "Nuclear bodies" "HPA011420: AB_1079170" "unprognostic (1.23e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.42e-5)" "unprognostic (2.17e-2)" "unprognostic (7.56e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.02e-7)" "unprognostic (4.70e-3)" "unprognostic (1.20e-1)" "unprognostic (6.24e-3)" "unprognostic (9.08e-3)" 13.3 3.4 7.7 11.0 6.9 0.5 6.9 6.0 11.2 5.0 5.8 8.0 1.3 30.7 2.3 5.1 7.9 20.3 13.5 8.0 6.9 7.5 5.1 3.1 5.7 9.5 8.1 12.3 10.3 1.8 10.3 6.7 9.3 4.4 2.0 3.3 2.7 5.5 5.4 3.2 3.6 37.5 6.9 4.5 12.5 1.1 7.5 0.7 9.4 3.2 1.1 10.7 3.8 8.0 0.0 0.8 0.0 164.3 36.6 3.7 0.2 4.0 3.8 0.8 1.8 0.0 0.2 0.0 0.0 2.5 5.8 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.3 0.0 4.5 0.0 0.1 6.3 0.0 5.5 0.0 0.0 0.0 0.1 0.0 0.2 6.7 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.4 0.1 0.1 0.4 6.4 0.1 12.1 0.7 0.1 0.0 0.0 3.8 0.1 3.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.7 6.9 6.0 11.2 8.0 6.9 9.5 8.1 9.3 6.9 7.5 8.0 8.2 0.0 2.2 4.2 0.0 3.8 0.4 0.2 0.0 0.1 1.8 0.4 4.9 0.0 1.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.8 16.3 19.8 4.8 0.0 0.0 0.0 0.2 32.3 9.2 0.6 3.8 0.4 3.9 0.2 0.1 3.3 0.3 0.0 2.0 0.0 5.8 0.3 21.1 1.0 32.0 5.6 0.0 6.1 0.0 1.0 0.0 0.4 0.1 17.0 0.4 1.4 0.0 0.0 3.7 0.7 118.3 1.7 128.3 0.1 0.2 0.4 3.1 0.3 0.6 0.1 0.2 1.8 KIRREL1 "KIRREL, NEPH1" ENSG00000183853 "Kirre like nephrin family adhesion molecule 1" Q96J84 1 157993273-158100262 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 6.2;Alveolar cells type 1: 19.2;Breast myoepithelial cells: 6.9;Endometrial stromal cells: 19.4;Fibroblasts: 7.2;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 169.8;WM-115: 262.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030458 Approved NA NA 890000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "HPA030458: AB_10601438" "unprognostic (8.92e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (3.76e-1)" "unprognostic (1.07e-3)" "unprognostic (7.96e-3)" "unprognostic (3.62e-2)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (2.77e-2)" "unprognostic (4.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (2.11e-3)" "unprognostic (5.24e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.85e-4)" 23.3 13.4 3.2 11.9 2.7 0.1 18.0 3.9 3.0 16.0 8.7 16.8 3.8 22.2 5.0 7.9 17.4 21.3 10.3 1.7 2.9 15.2 2.8 16.8 4.4 3.1 4.4 22.7 4.2 3.2 4.8 27.5 3.0 9.9 8.1 5.9 8.2 16.7 3.7 7.7 8.6 25.0 3.8 8.7 7.7 3.0 4.0 4.6 10.6 5.9 3.6 14.1 10.6 1.4 24.7 31.4 67.2 56.2 100.6 82.4 0.0 65.1 87.7 50.9 42.2 59.3 49.0 0.0 101.0 75.8 36.2 45.5 38.9 56.8 47.9 0.2 7.6 0.1 34.8 0.0 70.6 0.0 0.6 104.2 25.0 84.4 74.9 71.9 33.5 15.4 0.5 0.3 54.1 0.1 9.1 0.1 49.2 0.0 26.4 9.2 30.5 0.4 169.8 0.9 9.6 0.7 55.3 0.2 114.6 75.3 4.4 1.3 59.9 64.5 40.5 64.5 86.5 0.1 0.3 0.3 56.1 0.2 262.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.7 3.9 3.0 1.7 2.9 3.1 4.4 3.0 3.8 4.0 1.4 6.2 19.2 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 6.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 4.7 0.0 1.7 19.4 2.4 0.0 0.0 0.0 0.4 0.2 7.2 0.0 3.6 0.0 4.8 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.4 0.1 5.0 0.0 0.0 KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Collecting duct cells: 69.9;Excitatory neurons: 46.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 299.8;SK-BR-3: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" NA NA 260000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" 13.2 3.9 2.3 8.2 3.5 0.3 10.6 0.2 3.1 12.9 1.2 18.7 9.6 15.1 2.8 14.3 4.0 18.5 7.0 2.9 0.3 16.0 2.3 31.6 3.3 0.0 2.5 6.0 3.7 3.7 0.2 15.0 0.0 15.1 22.6 2.3 8.8 14.8 3.1 7.1 11.6 18.8 0.3 3.5 17.4 6.3 5.2 5.1 5.9 14.4 10.4 12.3 1.3 6.2 14.3 7.1 7.1 0.9 29.0 61.5 0.0 77.6 60.1 13.5 6.4 299.8 11.0 0.0 2.2 73.3 14.9 49.5 11.5 20.1 14.2 0.1 9.5 0.0 9.5 2.6 4.4 1.9 0.0 53.5 20.6 41.6 26.8 6.3 17.9 0.0 0.0 0.3 6.8 2.5 0.2 0.0 4.8 17.7 17.9 0.0 12.6 0.0 25.0 6.5 2.3 4.8 18.5 118.9 2.2 6.5 57.2 4.3 10.0 60.7 7.4 69.0 6.8 0.0 0.0 0.0 8.4 0.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.5 0.2 3.1 2.9 0.3 0.0 2.5 0.0 0.3 5.2 6.2 42.5 19.2 38.3 9.4 0.5 13.5 11.2 7.5 83.6 2.7 12.2 8.1 4.4 1.5 16.5 69.9 0.0 0.1 0.0 12.0 1.9 4.4 0.4 3.1 6.8 43.1 9.5 0.0 46.5 18.2 0.1 34.5 43.3 3.4 0.0 2.1 5.0 0.4 1.2 21.9 61.4 8.5 18.3 3.2 5.7 0.9 14.0 1.9 12.4 18.7 0.0 0.3 0.0 3.0 0.6 8.7 3.0 3.8 1.4 11.2 2.3 1.4 9.8 1.2 13.1 2.2 27.2 0.2 0.5 18.5 5.3 0.0 1.0 4.4 14.7 3.2 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.8;Leydig cells: 146.3;Peritubular cells: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 299.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 25000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" 75.2 73.2 12.8 18.2 14.2 2.6 58.2 15.1 14.9 68.0 47.7 63.1 24.6 72.7 25.5 31.9 63.8 62.2 169.1 13.1 14.5 41.3 31.7 55.1 16.9 20.0 14.8 94.4 32.7 104.7 15.4 99.0 15.4 50.4 18.0 11.7 40.3 81.0 67.5 40.9 32.5 80.2 14.1 29.8 48.4 21.4 17.3 6.7 60.2 70.0 12.8 52.2 55.9 13.5 15.7 38.7 34.4 122.0 196.3 201.5 31.1 131.9 161.8 73.8 75.7 18.3 52.0 0.2 44.4 299.0 38.3 49.3 30.0 47.6 52.3 0.1 9.5 6.9 63.4 32.1 132.5 0.3 0.3 176.9 69.4 61.6 62.1 184.3 75.9 0.0 4.1 0.1 61.4 30.3 0.1 0.3 15.1 20.7 32.0 0.2 16.6 0.5 53.5 19.1 0.2 20.4 74.9 42.9 68.3 57.5 93.4 0.9 126.9 82.2 34.9 28.5 35.4 0.1 0.4 0.4 39.1 0.3 57.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 14.2 15.1 14.9 13.1 14.5 20.0 14.8 15.4 14.1 17.3 13.5 83.7 118.6 53.5 26.1 2.4 31.2 13.9 33.6 33.0 1.7 39.4 40.5 151.8 37.1 43.6 55.2 6.2 11.3 0.9 3.6 5.9 26.4 3.5 15.4 24.4 77.8 0.0 0.4 0.2 9.4 6.4 120.1 50.4 27.2 1.3 88.9 94.9 49.9 10.4 8.4 0.4 3.1 32.6 10.1 31.1 12.3 146.3 7.5 42.7 15.9 3.5 46.7 2.1 1.0 0.6 14.1 14.9 140.7 0.5 10.2 16.4 28.6 11.2 2.6 118.3 80.8 92.3 4.3 8.6 14.2 24.4 9.4 3.8 27.6 5.6 9.3 LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.3" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 1531.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 574.7;CAPAN-2: 501.6;HBEC3-KT: 2492.2;hTERT-HME1: 1487.5;RPTEC TERT1: 579.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004257, HPA024638, HPA046539, CAB078165" Enhanced Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" No No 130000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" 3.5 0.1 0.2 16.2 1.9 0.1 20.9 2.6 0.6 15.1 0.2 12.1 2.6 12.3 2.1 7.7 34.9 13.0 3.0 0.2 0.2 13.8 0.7 24.9 8.0 0.0 0.1 1.0 3.3 0.0 4.2 10.9 0.1 5.4 12.9 0.1 12.9 6.1 1.7 17.5 15.0 3.3 0.0 0.9 14.9 2.8 0.1 11.3 18.5 2.3 12.3 39.3 6.3 0.2 574.7 25.4 0.0 0.7 4.9 11.9 40.2 4.3 4.7 2.1 0.7 41.4 501.6 0.0 207.9 1.4 16.4 252.4 0.1 2492.2 2.7 0.7 0.2 0.0 0.5 0.1 1.2 0.0 0.2 6.1 189.7 6.0 1487.5 2.3 32.6 0.0 0.0 0.2 2.5 1.1 0.0 0.1 4.5 206.7 35.2 0.1 1.2 0.0 579.4 147.1 30.5 0.1 14.7 0.4 0.9 14.9 2.0 2.7 3.8 2.2 30.2 15.0 7.8 0.9 0.7 0.7 4.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 2.6 0.6 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 218.0 17.8 0.0 0.2 86.3 227.1 232.7 105.3 0.0 8.2 26.2 2.3 10.0 56.8 23.9 0.0 30.7 0.4 74.4 0.0 183.4 19.6 68.9 3.6 7.8 9.0 0.0 0.4 94.0 11.7 17.2 59.7 97.4 0.0 0.0 0.0 0.0 2.5 0.0 0.3 34.1 14.2 0.0 4.9 11.8 3.4 3.1 8.8 1.0 2.6 0.0 0.0 0.0 0.3 1531.1 91.2 0.4 0.3 302.0 16.7 0.2 69.3 0.0 0.0 3.4 9.6 3.6 1.0 60.3 29.7 83.3 5.3 0.1 15.3 169.9 LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.3;Extravillous trophoblasts: 145.8;Fibroblasts: 76.0;Smooth muscle cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cell line enhanced" "Detected in many" "BJ: 66.5;BJ hTERT+: 75.2;hTERT-RPE1: 73.7;U-87 MG: 61.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" 12.4 3.1 1.4 5.4 0.8 0.8 6.8 0.2 1.4 12.7 12.3 10.2 1.9 16.0 1.4 4.7 8.3 5.0 27.9 1.7 1.9 8.7 1.5 10.1 4.4 1.4 1.7 8.0 3.3 2.2 9.2 8.0 1.1 15.3 1.4 0.0 7.6 11.9 3.8 6.4 5.6 4.9 0.8 3.2 7.8 2.4 1.9 0.9 5.2 1.9 2.3 16.6 14.8 0.6 3.3 0.0 0.9 0.0 45.6 54.8 2.2 66.5 75.2 27.6 48.7 1.3 1.7 0.0 12.1 49.1 6.9 19.9 0.3 0.2 6.5 0.0 4.3 0.2 2.0 0.3 6.2 0.0 0.1 45.0 0.0 20.8 0.2 73.7 1.0 1.2 0.0 0.3 33.3 2.4 0.4 1.3 6.3 4.4 45.1 0.0 38.7 0.6 2.5 12.0 5.5 0.0 2.0 0.4 0.0 6.5 0.4 0.0 4.9 53.8 47.0 42.8 25.8 0.2 0.0 0.0 61.9 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 1.3 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 3.4 0.2 1.4 0.8 0.2 1.4 1.7 1.9 1.4 1.7 1.1 0.8 1.9 0.6 4.1 0.0 0.6 3.3 0.1 5.9 7.6 6.0 4.0 0.9 2.3 4.8 92.3 2.8 0.9 9.2 0.0 2.2 0.6 0.1 3.9 5.2 1.7 9.2 8.0 4.1 3.5 0.0 0.5 1.3 145.8 76.0 8.6 9.3 1.3 5.5 12.1 0.1 6.6 0.0 0.4 0.6 2.0 0.0 6.2 1.3 9.9 0.9 10.6 0.0 0.1 6.4 0.0 1.5 0.3 12.2 0.1 21.1 0.1 4.8 0.4 2.5 1.2 0.4 0.0 6.0 32.7 8.9 4.9 2.4 3.4 5.1 3.4 0.3 1.1 5.0 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 LOXL4 "FLJ21889, LOXC" ENSG00000138131 "Lysyl oxidase like 4" Q96JB6 10 98247690-98268194 "Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Basal respiratory cells: 141.0" "Cancer enhanced" "Detected in all" "melanoma: 44.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BJ hTERT+: 249.7;CAPAN-2: 301.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033876, HPA037609" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB033876: AB_2135101, HPA037609: AB_2675579" "unprognostic (9.91e-3)" "unprognostic (3.97e-2)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (7.71e-2)" "unprognostic (1.75e-2)" "unprognostic (8.38e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.57e-4)" "unprognostic (2.51e-1)" "unprognostic (4.97e-2)" "unprognostic (5.25e-2)" "unprognostic (5.77e-3)" "unprognostic (1.28e-1)" "unprognostic (6.10e-2)" "unprognostic (7.40e-3)" 8.2 2.4 0.7 1.6 0.9 0.5 11.9 1.1 0.7 11.8 2.3 10.4 1.9 7.0 3.0 2.0 7.8 1.8 3.0 0.8 1.2 6.6 6.0 4.4 0.4 1.3 1.3 7.1 6.6 1.2 1.9 5.8 1.3 6.6 1.8 2.6 19.6 10.8 8.3 4.0 3.2 7.6 1.0 2.7 2.9 5.5 1.0 1.4 7.0 1.5 0.7 5.0 7.4 1.0 0.0 1.6 0.1 0.3 6.9 29.5 0.9 32.1 249.7 2.6 26.6 5.4 301.6 0.1 28.4 25.1 1.1 0.3 0.1 0.0 2.2 0.0 0.2 0.0 4.4 13.3 6.7 0.0 0.0 3.3 0.0 4.4 0.0 0.4 0.1 0.0 0.3 0.0 0.4 0.0 0.0 2.3 0.6 0.1 0.5 0.1 2.9 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 8.7 0.2 0.7 0.7 0.2 53.7 3.2 1.1 0.0 0.0 0.2 0.5 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.7 0.9 1.1 0.7 0.8 1.2 1.3 1.3 1.3 1.0 1.0 1.0 0.3 6.4 1.5 0.7 0.3 0.9 2.1 141.0 0.0 0.4 6.5 6.5 1.6 4.3 17.5 31.3 0.0 0.2 1.7 0.1 0.0 11.1 0.3 1.5 1.2 0.9 0.0 0.0 0.1 0.5 0.4 6.0 0.0 4.2 1.3 1.1 2.2 0.4 0.2 0.0 0.1 0.2 8.2 0.0 2.1 0.4 4.1 0.2 0.0 9.4 0.0 5.4 0.0 0.0 0.0 3.0 0.0 1.5 0.3 7.9 0.0 0.4 6.3 0.1 0.0 5.2 2.2 0.1 0.2 0.1 0.9 0.4 0.2 0.7 0.0 3.4 LRP6 ADCAD2 ENSG00000070018 "LDL receptor related protein 6" O75581 12 12116025-12267044 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 96.6;Oligodendrocyte precursor cells: 108.0;Oligodendrocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004490, HPA029925" Enhanced NA NA 390000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 68: Oligodendrocytes - Mixed function" "CAB004490: AB_627894, HPA029925: AB_10601768" "unprognostic (1.80e-1)" "unprognostic (3.72e-1)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (6.11e-2)" "unprognostic (1.07e-1)" "unprognostic (4.56e-2)" "unprognostic (1.37e-2)" "unprognostic (3.35e-2)" "unprognostic (6.98e-2)" "unprognostic (1.82e-1)" "unprognostic (5.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.44e-2)" "unprognostic (3.16e-1)" "unprognostic (1.23e-2)" "unprognostic (2.47e-1)" 3.7 2.2 2.0 1.2 3.9 0.2 4.5 2.5 2.0 6.6 13.5 4.6 2.8 6.5 1.9 2.0 4.4 2.8 3.3 2.0 2.8 4.4 7.9 4.6 0.8 2.2 2.7 5.4 4.9 6.2 2.6 8.3 1.7 3.4 2.8 2.8 6.8 3.2 4.5 3.4 2.7 4.1 1.8 0.9 3.4 2.1 2.8 1.2 4.5 4.6 1.0 3.4 5.3 2.9 3.9 13.3 9.9 5.3 6.1 4.0 7.8 5.8 5.4 4.6 5.3 6.5 3.6 0.0 2.8 5.6 3.8 3.7 14.6 3.7 8.7 0.0 3.9 4.1 4.9 3.2 2.1 5.7 2.8 3.2 2.0 6.9 5.4 5.1 4.8 4.1 5.0 0.0 3.0 3.2 4.2 1.1 14.4 2.2 1.7 5.3 9.2 1.0 6.8 7.6 2.0 5.6 7.4 2.5 6.0 11.5 2.0 3.7 6.9 3.6 13.2 2.6 4.9 0.0 0.0 1.9 2.9 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.9 2.5 2.0 2.0 2.8 2.2 2.7 1.7 1.8 2.8 2.9 21.6 41.7 49.5 96.6 1.0 15.4 8.6 11.9 9.6 28.2 20.1 19.0 15.4 11.5 16.6 14.7 22.9 3.7 0.5 20.4 1.9 9.0 1.0 18.0 39.0 25.9 10.8 0.4 58.2 13.7 3.2 24.0 25.5 29.1 0.0 32.8 22.1 46.7 2.3 6.7 58.0 12.9 10.2 2.4 6.0 5.1 30.4 1.7 14.2 35.6 0.6 19.9 1.0 108.0 97.0 11.3 20.5 38.7 1.6 14.7 15.1 5.2 6.0 29.0 0.0 21.5 17.3 21.5 26.4 11.0 13.8 3.4 1.9 23.7 14.4 8.1 LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Fibroblasts: 116.1;Leydig cells: 90.4;Peritubular cells: 161.0;Skeletal myocytes: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 569.4;HSkMC: 185.3;HUVEC TERT2: 194.5;U-2197: 181.1;U-87 MG: 255.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" 22.9 13.1 7.8 22.1 9.4 11.5 14.5 7.1 7.5 161.4 10.5 27.2 10.2 58.9 37.8 21.2 37.0 73.0 89.0 8.8 9.1 38.6 18.6 27.5 6.9 12.1 10.6 30.2 7.9 2.4 9.0 73.2 9.2 46.9 16.5 0.7 14.6 73.6 15.7 10.8 15.0 96.7 9.1 8.3 32.8 17.9 8.8 8.2 6.5 28.4 18.7 53.9 28.3 13.4 0.3 12.5 31.3 0.3 26.1 569.4 13.5 46.5 95.7 6.4 9.3 25.3 4.6 41.3 1.0 6.0 8.8 2.4 0.7 1.5 22.0 0.6 15.3 135.6 15.0 4.1 118.6 0.5 15.7 185.3 4.4 141.2 6.9 61.8 194.5 6.3 8.7 0.3 51.1 19.9 5.5 0.2 22.4 1.0 39.2 4.7 65.8 0.6 0.4 22.4 6.3 3.4 9.5 72.1 0.8 49.1 27.9 0.4 126.4 6.4 26.2 181.1 37.6 74.8 80.0 58.8 255.9 5.2 10.8 3.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 5.3 7.8 9.4 7.1 7.5 8.8 9.1 12.1 10.6 9.2 9.1 8.8 13.4 33.6 0.0 0.6 108.4 0.4 13.5 5.6 13.0 10.2 0.0 6.9 6.6 80.9 4.3 3.6 1.8 0.0 45.2 0.3 12.9 0.0 9.6 6.3 7.3 18.3 28.1 1.2 30.3 30.4 6.5 23.4 116.1 10.2 10.5 0.0 11.8 20.3 11.0 7.6 0.0 54.3 2.8 2.0 0.3 18.1 7.1 90.4 12.0 19.6 39.4 0.4 0.2 0.0 70.4 52.4 19.1 3.3 161.0 1.3 19.1 0.7 0.3 6.3 0.3 59.2 85.8 67.9 0.7 11.9 6.9 9.8 43.5 2.0 2.6 4.1 33.4 MAST4 KIAA0303 ENSG00000069020 "Microtubule associated serine/threonine kinase family member 4" O15021 5 66596361-67169595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Astrocytes: 519.7;Basal prostatic cells: 507.3;Excitatory neurons: 636.6;Inhibitory neurons: 489.6;Suprabasal keratinocytes: 399.2;Urothelial cells: 676.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 27.7" "Immune cell enhanced" "Detected in many" "basophil: 15.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 33.2;HDLM-2: 43.2;HEL: 35.5;RT4: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000544 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "HPA000544: AB_1079315" "unprognostic (1.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (4.99e-3)" "unprognostic (2.83e-2)" "prognostic favorable (5.18e-5)" "unprognostic (9.01e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-2)" "unprognostic (9.47e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (1.37e-2)" "unprognostic (2.63e-1)" "unprognostic (2.63e-1)" "unprognostic (3.08e-2)" 14.9 11.0 4.6 4.5 5.2 1.9 11.1 0.9 27.7 12.1 0.0 6.0 5.1 10.0 5.0 27.0 9.4 8.0 29.5 4.2 5.4 12.0 8.4 11.0 4.4 5.0 5.5 16.4 4.6 15.3 4.6 8.8 1.2 7.6 4.1 4.7 11.5 6.6 11.2 14.8 4.5 9.3 1.1 5.0 7.0 10.0 3.3 16.8 6.5 7.2 10.1 16.0 21.2 11.4 14.6 7.8 3.8 0.2 12.4 10.9 9.0 3.2 4.9 1.1 1.0 7.3 3.9 1.0 6.5 2.7 2.9 12.8 11.8 33.2 1.3 43.2 3.8 35.5 4.7 3.1 0.9 0.1 11.9 18.4 17.8 7.1 14.2 13.3 26.2 3.2 3.5 3.9 8.9 12.6 5.1 0.2 2.5 1.2 6.3 1.1 3.3 0.7 3.1 42.9 5.5 4.4 4.3 1.7 0.2 2.7 2.8 0.2 25.2 3.0 4.1 4.6 5.4 9.9 4.8 0.2 7.7 0.1 2.4 15.2 0.3 0.8 0.9 0.4 2.5 2.9 4.0 1.0 0.4 2.5 4.2 1.8 3.5 2.3 0.9 1.0 6.9 1.3 4.6 5.2 0.9 27.7 4.2 5.4 5.0 5.5 1.2 1.1 3.3 11.4 130.2 32.1 53.3 519.7 11.4 368.6 507.3 127.9 114.9 15.9 79.3 38.1 139.1 27.1 78.7 18.4 2.1 40.7 4.9 24.4 37.2 59.0 129.2 35.8 5.3 111.8 32.2 5.5 636.6 115.8 50.0 33.2 28.5 55.3 93.8 19.4 70.6 42.2 5.1 8.4 489.6 18.1 40.7 6.9 33.7 127.4 41.3 9.8 48.0 78.7 2.1 55.2 4.1 165.9 108.4 70.8 27.2 32.7 13.5 355.5 14.8 93.9 57.2 4.5 39.5 15.9 31.1 14.8 9.2 211.7 399.2 137.2 21.0 14.7 16.1 676.4 MCAM "CD146, HEMCAM, MelCAM, METCAM, MUC18" ENSG00000076706 "Melanoma cell adhesion molecule" P43121 11 119308529-119321521 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 128.5;Endothelial cells: 153.5;Muller glia cells: 89.8;Sertoli cells: 322.1;Smooth muscle cells: 384.6" "Cancer enhanced" "Detected in all" "melanoma: 83.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HUVEC TERT2: 1121.0;TIME: 1107.4;WM-115: 869.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002147, HPA008848" Enhanced Approved "Plasma membrane" NA NA 1900000000 "Cluster 13: T-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB002147: AB_563499, HPA008848: AB_1078445" "unprognostic (6.45e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (7.03e-2)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (8.42e-2)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.39e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (8.75e-3)" "unprognostic (7.84e-2)" "unprognostic (2.31e-1)" "unprognostic (2.79e-3)" 332.7 30.0 36.6 68.4 46.1 1.2 180.6 45.7 45.3 96.6 25.3 166.3 29.2 175.8 47.0 89.2 136.4 66.8 118.0 35.3 44.7 42.0 10.5 116.4 19.6 59.4 43.1 60.9 22.0 93.9 17.8 168.0 52.2 78.1 32.2 12.2 39.5 148.0 40.7 50.9 73.0 160.9 36.2 35.4 97.7 9.7 50.2 15.5 58.7 37.4 15.4 174.5 79.8 44.8 0.7 5.1 4.7 0.3 21.5 0.3 23.2 3.2 0.3 29.9 13.3 17.9 0.9 1.2 94.5 10.7 44.7 3.2 38.3 8.1 15.0 56.9 14.5 1.2 102.4 19.8 51.0 0.1 0.4 15.2 0.3 40.8 18.7 1.1 1121.0 7.1 38.7 1.5 6.1 0.0 1.2 9.3 19.9 0.2 4.4 0.9 147.8 32.9 27.1 0.0 12.5 3.9 87.1 2.1 249.2 46.2 4.3 0.9 1107.4 3.1 156.7 0.2 89.1 2.4 2.3 0.6 43.1 0.1 869.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 36.6 46.1 45.7 45.3 35.3 44.7 59.4 43.1 52.2 36.2 50.2 44.8 128.5 0.0 2.3 1.3 1.4 4.7 0.6 11.1 8.0 1.2 9.9 19.7 65.8 18.6 1.1 0.0 22.9 0.5 2.5 0.1 0.0 17.3 1.7 7.8 14.0 153.5 0.0 0.0 1.4 0.4 38.7 14.1 1.5 10.3 0.0 18.2 60.0 0.6 0.8 0.0 3.5 0.0 0.0 1.3 7.0 0.7 0.9 2.4 21.4 14.0 0.6 89.8 1.0 18.6 45.2 1.6 0.0 25.2 3.1 1.7 0.0 0.9 1.3 4.0 322.1 9.9 384.6 2.1 1.6 1.7 3.3 0.4 9.3 4.9 0.1 1.8 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 197.8;Fibroblasts: 75.8;Granulosa cells: 93.3;Leydig cells: 53.7;Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 249.4;ASC TERT1: 249.6;HUVEC TERT2: 263.1;SH-SY5Y: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" 36.6 4.2 0.4 13.3 0.6 0.1 22.7 0.5 1.1 81.8 1.6 15.0 5.0 61.4 22.1 6.1 19.0 73.2 13.8 0.5 0.6 9.4 1.6 20.1 4.2 0.7 0.9 35.8 18.8 4.5 13.2 42.4 0.7 22.1 4.8 4.9 16.5 12.1 2.6 27.6 12.1 30.6 0.5 2.7 8.3 11.2 0.7 1.6 9.5 3.0 2.3 22.5 36.7 0.6 0.0 0.2 93.2 0.3 249.4 249.6 6.2 26.3 102.5 39.7 73.7 24.1 1.1 0.0 82.6 89.7 0.1 0.1 7.2 7.7 15.9 0.1 78.0 0.0 37.1 2.1 23.4 0.1 0.1 104.4 18.8 109.4 42.7 113.1 263.1 0.0 0.2 16.2 19.2 12.5 0.1 0.1 108.8 0.5 0.8 1.5 0.0 4.0 0.9 0.3 5.0 212.1 9.0 36.6 9.6 71.1 11.9 13.0 75.6 65.6 128.4 51.7 2.8 0.1 0.3 0.2 53.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.5 1.1 0.5 0.6 0.7 0.9 0.7 0.5 0.7 0.6 5.5 0.0 1.7 0.0 0.1 6.6 7.8 28.7 8.0 0.2 2.1 3.9 0.9 2.8 10.7 3.7 0.0 4.5 0.0 0.1 0.0 1.3 12.9 5.6 28.7 7.1 10.1 0.0 0.0 0.8 197.8 75.8 2.0 8.3 0.0 93.3 1.4 0.0 7.4 0.0 0.0 0.4 12.2 0.0 7.7 7.6 53.7 0.6 17.8 2.8 0.0 27.7 0.0 0.0 0.0 1.9 0.0 63.9 0.5 1.5 0.0 0.0 1.9 0.8 0.0 3.3 14.7 3.2 8.7 0.6 6.3 29.0 0.9 0.5 0.2 1.2 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 242.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.5;Extravillous trophoblasts: 1015.1;Fibroblasts: 579.7;Syncytiotrophoblasts: 252.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 31.7" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 172.2;BJ: 63.7;EFO-21: 150.4;HeLa: 55.9;SuSa: 137.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 42.6" HPA010553 Enhanced "Secreted to extracellular matrix" NA NA 3200000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" 141.7 10.9 3.5 5.4 5.0 3.5 79.7 31.7 9.2 59.9 1.8 37.8 7.2 242.1 11.1 35.0 25.8 28.2 54.4 4.8 0.8 3.1 12.7 8.7 4.8 2.9 0.4 2.4 5.5 2.4 3.7 94.5 1.9 6.4 42.0 7.9 17.2 49.7 28.5 38.7 19.0 142.1 0.0 1.9 23.6 6.9 1.7 3.2 14.4 118.1 3.4 43.1 60.7 6.6 1.4 5.7 1.6 2.6 29.4 12.4 172.2 63.7 1.2 0.8 1.1 2.3 1.0 0.6 150.4 19.8 1.6 9.1 0.6 13.1 0.0 0.5 0.4 1.6 55.9 1.9 0.4 1.3 0.6 8.7 4.4 7.3 0.0 3.3 0.0 2.0 2.7 3.7 52.7 0.8 1.9 0.8 3.2 0.9 2.9 1.2 1.3 6.5 6.5 2.6 0.7 0.9 1.9 0.7 1.0 137.1 24.0 0.8 2.3 10.7 21.5 45.7 3.0 2.1 1.9 2.3 6.0 0.7 0.1 2.9 0.8 0.7 0.2 0.7 0.4 0.1 0.1 0.1 0.4 0.3 0.4 0.1 1.1 0.2 0.5 0.3 0.0 0.3 3.5 5.0 31.7 9.2 4.8 0.8 2.9 0.4 1.9 0.0 1.7 6.6 61.5 12.8 5.8 0.3 0.5 23.1 0.4 1.8 0.6 0.2 0.6 0.9 7.0 0.0 2.0 0.0 0.0 140.5 0.5 0.0 0.0 0.5 0.3 5.1 3.9 20.1 0.0 0.0 0.2 0.0 1015.1 579.7 3.6 28.0 0.0 0.2 4.2 0.0 27.7 0.0 0.1 0.0 0.0 9.5 36.3 0.5 61.2 8.8 12.4 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.6 0.1 0.0 0.2 1.6 0.9 0.0 40.2 35.2 0.1 0.2 0.6 18.0 252.3 5.3 0.1 0.0 0.3 MGP ENSG00000111341 "Matrix Gla protein" P08493 12 14880864-14885857 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 9375.3;Breast myoepithelial cells: 4639.0;Fibroblasts: 4233.6;Hepatic stellate cells: 1826.5;Leydig cells: 2016.2" "Cancer enriched" "Detected in all" 5 "breast cancer: 845.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.6" "Cell line enriched" "Detected in many" 5 "AN3-CA: 9874.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013949 Approved "Secreted to blood" NA NA 29000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "HPA013949: AB_1853599" "unprognostic (5.71e-3)" "unprognostic (5.85e-3)" "unprognostic (1.20e-3)" "unprognostic (2.83e-2)" "unprognostic (1.27e-1)" "unprognostic (1.21e-1)" "unprognostic (1.55e-2)" "unprognostic (4.17e-3)" "unprognostic (1.01e-2)" "unprognostic (6.93e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-2)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.55e-2)" "unprognostic (4.69e-2)" "unprognostic (7.50e-2)" "unprognostic (8.97e-3)" 1737.5 1510.2 50.6 187.4 63.8 1.6 3734.8 48.9 253.3 1738.8 198.1 1827.5 69.8 2043.8 752.9 218.2 2280.1 1083.5 2854.4 49.0 48.2 1316.9 58.1 1269.6 107.0 57.0 49.1 838.7 218.9 109.7 923.0 204.2 51.2 1955.5 277.3 7.5 2112.7 1140.7 177.0 357.6 819.0 1310.0 53.9 142.2 905.9 142.3 58.4 99.5 1500.7 275.0 65.9 987.7 1266.3 48.8 0.9 0.0 0.1 9874.6 1624.2 2.4 3.7 31.8 1.0 0.0 0.0 0.0 12.7 0.2 0.5 3.1 0.4 0.1 0.2 0.2 0.0 0.3 0.3 0.0 1.3 0.0 55.0 0.2 0.2 33.6 0.0 0.0 1.5 3.2 105.4 0.0 0.0 0.3 0.0 0.9 1.2 4.8 7.0 2.2 0.0 0.4 0.2 2.6 0.0 10.5 4.8 31.1 2.0 8.9 0.6 2.8 1810.9 0.1 21.7 11.1 1.2 3.6 28.7 0.5 0.1 1.1 9.0 0.6 8.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 50.6 63.8 48.9 253.3 49.0 48.2 57.0 49.1 51.2 53.9 58.4 48.8 451.0 19.2 72.8 1.3 29.9 149.3 220.4 0.3 19.9 0.5 9375.3 4639.0 70.2 8.6 187.5 115.8 4.2 19.0 85.7 0.1 1.9 2.3 16.9 14.7 355.8 856.1 0.0 18.7 0.2 83.4 13.5 4233.6 86.2 10.9 13.9 0.3 1826.5 6.0 30.8 0.0 0.1 0.0 0.0 9.4 219.9 67.9 2016.2 36.1 225.9 23.4 2.6 28.8 0.0 0.0 0.2 1.8 1.1 1301.8 17.0 164.3 0.0 0.7 25.8 6.8 841.5 558.8 847.0 8.2 6.1 25.8 118.5 39.5 54.5 140.6 0.0 74.6 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.0;Pancreatic endocrine cells: 144.7;Syncytiotrophoblasts: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 923.8;HHSteC: 794.2;HSkMC: 887.0;hTERT-RPE1: 925.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 151.5 31.7 5.6 59.9 5.0 1.6 101.5 5.7 7.5 181.3 61.8 77.2 39.5 167.3 19.0 92.1 82.1 148.2 41.3 6.6 7.2 35.9 13.2 91.8 24.8 11.9 8.4 90.2 36.0 65.3 14.2 118.9 9.2 59.9 36.6 9.6 78.1 45.5 18.8 127.5 69.4 106.0 7.3 30.8 57.7 11.7 13.2 13.0 50.0 16.1 30.8 103.9 111.1 10.6 90.6 1.2 26.3 2.0 923.8 651.6 455.9 270.1 606.4 93.3 158.5 21.3 337.4 0.9 146.4 301.9 24.6 216.3 0.3 262.2 99.7 1.1 0.6 37.2 1.7 5.0 794.2 0.4 1.3 887.0 148.7 334.7 288.3 925.5 492.9 0.6 0.8 2.1 185.1 0.7 0.4 79.4 14.7 17.7 52.4 2.1 96.0 0.2 61.4 148.1 0.3 0.6 187.3 0.3 574.2 104.4 1.0 79.5 436.8 724.9 53.7 198.2 329.6 0.8 1.6 1.1 410.9 0.6 396.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 5.0 5.7 7.5 6.6 7.2 11.9 8.4 9.2 7.3 13.2 10.6 13.9 12.8 3.0 2.0 3.4 34.0 23.4 105.4 39.3 0.0 14.1 17.5 4.7 50.1 42.2 7.3 0.0 105.6 0.3 19.9 11.7 63.0 0.4 16.1 81.6 35.2 7.8 0.0 0.0 28.7 244.0 84.0 25.5 14.8 3.8 9.3 32.9 2.7 89.5 0.0 0.0 24.5 34.6 20.2 32.7 2.4 72.1 38.0 37.4 4.7 21.5 14.3 0.0 0.5 0.1 144.7 33.0 54.9 0.3 21.8 19.9 11.7 46.8 0.8 39.5 11.1 73.9 0.8 0.8 33.7 34.2 122.7 2.5 15.6 18.6 37.9 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MPZ "CMT1, CMT1B, CMT2I, CMT2J, HMSNIB, P0" ENSG00000158887 "Myelin protein zero" P25189 1 161304735-161309968 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Skeletal myocytes: 9.3" "Cancer enriched" "Detected in many" 11 "melanoma: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "WM-115: 139.3" "Group enriched" "Detected in some" 4 "olfactory bulb: 2.9;pons and medulla: 1.3" "Region enriched" "Detected in some" 10 "spinal cord: 2142.4" HPA068925 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "HPA068925: AB_2732123" "unprognostic (6.77e-2)" "unprognostic (2.98e-1)" "unprognostic (9.27e-2)" "unprognostic (1.46e-1)" "unprognostic (3.35e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-2)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "unprognostic (7.88e-3)" "unprognostic (1.51e-1)" "unprognostic (6.62e-8)" "unprognostic (6.75e-2)" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (8.32e-2)" 19.1 6.9 2.1 2.1 3.0 1.1 12.6 2.5 2.7 8.3 1.4 22.3 1.6 2.0 2.0 4.4 5.3 2.4 15.2 1.9 3.9 6.3 5.4 2.9 1.1 3.0 2.2 3.1 2.3 0.6 6.2 0.6 9.9 12.2 2.7 1.2 15.8 8.0 5.1 9.1 8.5 0.8 3.3 4.4 7.6 2.4 2.0 1.4 3.7 18.4 0.9 9.5 15.9 2.2 0.4 0.0 0.3 0.1 2.7 1.3 0.3 0.3 0.5 0.1 1.6 0.0 0.1 2.3 1.5 0.4 0.5 0.1 1.8 0.6 0.1 1.1 0.0 1.0 0.4 31.0 1.2 4.7 3.7 4.2 0.0 6.2 0.3 0.0 2.8 1.9 9.9 0.0 4.3 0.0 0.7 7.6 1.4 0.0 0.0 0.3 0.2 1.4 0.3 0.1 2.0 0.3 0.0 0.0 14.0 0.8 0.1 9.5 2.7 0.3 0.4 2.7 0.2 0.9 0.9 1.2 4.8 17.5 139.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 3.0 2.5 2.7 1.9 3.9 3.0 2.2 9.9 3.3 2.0 2.2 1.7 3.2 0.6 1.0 2.1 0.5 3.1 0.4 4.0 2.5 0.4 1.3 0.7 0.0 0.5 3.7 2.1 0.5 1.6 0.1 0.0 0.2 5.5 0.3 0.2 1.5 1.8 1.3 1.7 1.2 0.7 2.5 0.0 0.1 0.0 0.8 1.8 1.0 1.6 1.7 2.2 0.7 2.0 1.9 0.8 1.8 1.5 2.0 3.6 1.0 3.8 0.5 0.0 0.5 1.6 0.1 0.1 0.4 1.4 0.9 0.3 1.0 0.6 1.1 6.6 9.3 3.9 0.4 0.6 1.1 0.4 0.3 1.6 0.4 0.4 2.0 MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 183.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 183.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA026966: AB_10600931, HPA063538: AB_2685034" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.59e-2)" "unprognostic (4.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.27e-6)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.99e-7)" "unprognostic (3.55e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (4.21e-2)" 74.8 34.1 23.1 49.2 21.6 8.3 91.6 22.0 21.8 63.1 40.1 60.1 40.8 50.0 27.4 52.9 60.1 67.7 52.4 22.1 28.3 28.6 23.0 42.3 35.2 25.7 30.0 46.4 27.5 28.4 33.0 68.9 30.7 41.8 59.4 12.7 73.1 38.9 14.7 34.0 41.0 62.6 26.4 29.2 43.8 48.2 28.6 29.3 39.5 26.8 45.9 74.7 51.3 24.9 88.5 126.3 96.9 75.8 303.4 137.2 304.8 134.5 172.7 86.3 106.4 234.4 119.5 31.0 152.9 171.6 76.1 144.2 97.5 149.0 72.6 70.9 52.8 25.5 63.5 56.7 188.5 30.2 16.1 126.1 183.5 137.8 153.4 121.4 116.4 93.6 97.1 63.5 103.0 29.3 103.6 36.2 61.9 176.7 53.5 62.5 82.7 137.5 131.4 84.6 55.7 91.8 119.6 122.4 69.7 221.9 66.6 16.0 132.8 97.9 44.1 127.5 73.8 94.0 157.2 142.8 140.8 35.3 15.8 7.7 29.1 20.0 2.8 24.8 1.3 14.7 2.8 4.1 38.5 8.8 7.7 2.6 183.8 10.4 34.6 43.9 0.5 11.0 23.1 21.6 22.0 21.8 22.1 28.3 25.7 30.0 30.7 26.4 28.6 24.9 52.9 28.9 30.0 31.0 15.1 76.3 78.5 57.6 35.9 8.8 75.9 73.9 6.3 20.0 49.6 20.2 6.2 128.7 21.1 67.1 5.9 63.2 1.8 14.5 40.4 56.7 47.8 10.1 32.8 75.6 145.2 118.2 41.3 23.0 3.8 75.3 24.3 23.3 37.7 10.1 27.9 39.7 20.3 28.2 31.9 4.9 69.9 23.5 16.0 60.0 84.0 11.8 3.1 141.8 1.7 81.0 41.6 83.8 23.5 141.7 55.5 10.1 28.3 13.9 19.7 18.6 48.6 8.9 26.8 41.2 55.5 76.9 8.6 49.4 61.0 57.7 MRTFB "FLJ31823, MKL2, MRTF-B" ENSG00000186260 "Myocardin related transcription factor B" Q9ULH7 16 14071319-14266773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 43.9;Cardiomyocytes: 26.9;Cytotrophoblasts: 9.9;Endothelial cells: 9.6;Extravillous trophoblasts: 10.0;Smooth muscle cells: 14.9;Syncytiotrophoblasts: 10.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 170 "amygdala: 9.4;basal ganglia: 15.1;cerebral cortex: 21.4;hippocampal formation: 21.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011286 Enhanced Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA011286: AB_1853973" "unprognostic (2.00e-1)" "unprognostic (5.28e-1)" "unprognostic (1.30e-2)" "unprognostic (3.62e-1)" "unprognostic (7.16e-2)" "unprognostic (7.14e-3)" "unprognostic (1.21e-1)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-1)" "unprognostic (3.19e-1)" "unprognostic (2.32e-1)" "prognostic favorable (6.20e-4)" "unprognostic (5.22e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (5.96e-2)" 21.4 7.3 9.4 8.6 15.1 3.8 18.3 0.0 21.4 19.0 0.0 9.9 9.7 14.9 9.1 14.5 14.0 13.3 11.8 21.7 0.0 8.4 5.9 13.2 7.6 0.0 0.0 7.1 12.1 22.2 4.9 21.7 0.0 15.5 10.8 8.6 11.6 15.2 11.9 16.6 7.9 15.6 0.0 5.1 10.1 17.5 0.0 10.3 16.9 14.5 8.1 11.3 12.2 0.0 17.6 17.8 17.8 13.2 5.9 11.0 8.0 4.9 13.3 7.4 10.6 7.7 16.4 9.4 12.4 8.4 9.3 13.8 12.9 14.4 13.5 23.1 7.0 6.0 13.6 13.3 8.2 4.2 5.4 8.4 14.6 12.8 8.3 7.8 14.7 12.2 7.9 9.7 5.6 15.1 13.4 2.8 6.0 4.7 4.8 20.5 13.7 8.1 7.3 17.3 6.2 10.8 23.9 10.2 4.9 8.2 18.0 3.5 9.4 15.3 14.9 4.4 6.4 6.6 8.8 8.4 16.6 7.1 11.7 0.2 0.5 0.0 1.1 0.7 1.7 3.7 1.9 0.9 0.7 1.5 2.4 1.3 0.3 1.1 0.8 1.7 0.9 0.6 9.4 15.1 0.0 21.4 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 9.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 10.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 10.4 0.4 0.0 0.0 0.0 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 3800000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: AB_2667469" "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 169.3 27.0 12.4 34.4 11.8 4.9 115.9 13.3 12.7 77.4 17.1 104.9 47.4 97.1 21.5 64.7 66.4 46.1 97.5 10.2 14.7 56.8 39.5 87.2 24.1 14.8 11.2 43.6 69.3 34.3 22.9 56.9 14.6 69.9 41.7 2.1 91.7 58.2 49.5 57.7 65.6 65.7 11.9 30.8 76.3 17.1 13.7 21.3 60.6 35.8 25.1 86.3 67.8 10.8 169.8 182.1 19.3 79.5 88.8 87.6 74.2 168.6 138.9 108.7 91.0 122.3 90.7 16.9 118.7 261.1 72.7 139.9 29.2 117.2 56.3 75.2 74.5 16.2 96.4 46.2 131.7 1.6 81.5 68.7 57.3 100.2 57.3 99.5 141.7 10.5 13.1 13.7 93.5 129.5 1.9 1.4 12.4 105.8 34.0 6.9 26.4 30.7 100.5 86.9 7.8 43.0 105.9 152.6 67.4 47.5 125.3 8.7 187.9 156.6 119.1 77.7 147.8 10.7 9.1 7.2 124.7 4.1 138.8 0.1 0.9 0.0 0.9 2.0 0.4 4.8 2.1 0.9 1.1 3.8 0.7 0.4 0.5 0.0 1.7 1.0 1.9 1.5 12.4 11.8 13.3 12.7 10.2 14.7 14.8 11.2 14.6 11.9 13.7 10.8 133.7 125.0 35.9 5.5 20.8 39.8 38.2 27.8 31.9 4.1 44.0 33.0 75.4 48.6 36.3 86.5 0.0 57.8 2.5 159.0 21.5 62.3 17.4 26.3 44.4 78.0 39.5 13.5 2.5 52.0 28.4 51.8 66.3 75.5 12.0 25.4 83.6 38.5 20.0 5.0 3.8 111.8 14.2 14.5 43.4 11.4 42.3 16.7 64.0 15.0 20.3 5.6 0.0 2.5 1.0 92.8 88.7 48.5 12.8 64.7 92.8 15.4 12.9 2.1 118.3 37.7 90.6 9.4 7.5 39.5 42.6 47.6 10.0 10.6 88.1 39.2 MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 123.4;Pancreatic endocrine cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.6" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 452.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane" NA NA 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Plasma membrane" "HPA014245: AB_1848495" "unprognostic (3.41e-2)" "unprognostic (3.85e-1)" "unprognostic (2.88e-2)" "unprognostic (7.44e-2)" "unprognostic (3.50e-2)" "unprognostic (8.57e-3)" "unprognostic (3.48e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (5.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.94e-2)" "unprognostic (9.17e-2)" "unprognostic (9.18e-2)" 31.7 8.1 2.9 20.6 4.1 1.5 43.3 5.0 2.5 56.4 37.4 22.4 5.3 27.5 7.1 36.4 36.9 26.6 13.8 3.4 4.1 10.9 2.9 32.2 4.4 8.9 6.8 9.8 5.9 23.8 3.8 55.2 8.1 27.5 29.3 0.9 19.7 31.4 3.6 56.1 9.0 44.3 6.2 6.5 13.4 2.2 5.4 5.1 35.7 6.2 9.1 62.0 29.4 6.2 228.9 206.3 21.4 14.6 159.4 318.4 62.0 190.3 452.7 110.1 109.2 51.1 177.1 0.0 76.9 353.7 116.2 350.0 1.8 204.7 82.6 1.4 0.9 0.0 80.8 2.1 55.2 0.0 0.2 183.0 71.6 77.7 323.8 289.4 299.7 0.0 0.0 0.5 275.6 39.4 0.1 0.9 1.6 72.0 171.6 0.0 15.8 0.1 314.3 281.5 0.1 0.0 130.4 29.7 46.1 83.1 141.5 4.7 378.5 167.3 11.8 111.3 113.9 0.2 0.3 0.3 128.2 2.6 201.0 0.0 5.4 0.0 0.0 20.4 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.3 0.0 26.6 2.8 0.2 1.6 2.9 4.1 5.0 2.5 3.4 4.1 8.9 6.8 8.1 6.2 5.4 6.2 42.5 60.9 52.5 1.6 1.2 23.7 63.0 101.4 39.3 0.1 48.4 34.3 9.2 14.3 91.5 22.0 0.0 56.6 3.8 74.1 1.9 54.8 0.6 50.9 45.9 28.8 1.8 0.0 2.7 33.7 23.7 38.1 23.0 123.4 1.3 1.7 35.7 0.4 22.9 0.0 0.8 29.6 42.7 29.2 20.2 0.6 5.9 28.5 8.8 60.0 12.8 0.1 0.0 2.0 0.7 153.7 22.2 9.1 0.8 86.7 0.6 1.5 60.7 0.8 6.6 15.9 39.6 0.1 0.3 53.4 30.7 51.2 1.9 8.3 18.7 100.7 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 82.8;Distal enterocytes: 82.5;Endothelial cells: 53.8;Leydig cells: 54.7;Paneth cells: 42.1;Proximal enterocytes: 53.4;Smooth muscle cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 43.7;T-47d: 20.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 46: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 25.0 16.0 8.4 5.2 10.3 2.0 21.1 2.3 24.1 18.3 3.4 28.4 6.9 24.7 24.1 13.5 22.0 11.7 32.2 17.1 6.9 11.0 6.0 12.6 3.7 3.5 4.6 14.7 5.3 3.2 8.2 6.1 3.8 17.6 13.7 0.3 6.6 32.1 14.0 18.1 17.6 20.4 3.6 0.7 7.7 4.3 6.3 5.9 10.3 16.0 3.9 25.7 17.3 6.5 7.2 3.7 2.0 8.9 0.6 0.3 0.1 8.0 3.5 4.1 6.0 13.7 3.2 0.0 2.1 5.2 5.0 2.1 0.7 3.6 2.8 13.2 0.5 9.8 13.3 0.1 0.6 0.0 2.9 0.0 15.1 0.9 4.1 1.2 0.6 1.4 0.0 3.0 8.9 8.0 2.3 0.2 1.3 3.1 0.3 43.7 9.4 1.4 0.1 1.6 1.6 8.9 7.6 11.9 0.3 3.5 20.0 1.5 1.3 3.1 18.1 2.2 5.1 1.2 0.4 0.0 9.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.3 2.3 24.1 17.1 6.9 3.5 4.6 3.8 3.6 6.3 6.5 82.8 0.0 1.9 0.3 0.6 4.8 0.7 3.0 0.6 0.6 1.5 1.3 9.3 1.5 4.8 0.0 0.0 0.3 0.4 82.5 0.0 0.7 2.6 1.9 2.5 53.8 13.9 11.4 5.2 0.7 0.2 10.3 2.0 0.6 0.0 4.9 30.4 0.3 0.3 0.0 1.0 10.2 2.0 1.9 2.6 6.6 54.7 2.2 7.2 4.7 0.7 0.7 0.0 5.0 13.0 4.5 42.1 12.4 0.1 1.9 53.4 0.8 12.8 0.3 26.3 11.6 58.8 2.5 3.4 7.7 5.4 0.1 0.7 2.5 20.0 1.2 NIBAN1 "C1orf24, FAM129A, GIG39, NIBAN" ENSG00000135842 "Niban apoptosis regulator 1" Q9BZQ8 1 184790724-184974508 "Cancer-related genes, Predicted intracellular proteins" "Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 164.1" "Cell type enriched" "Detected in some" 13 "Cardiomyocytes: 692.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 72.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 72.1" "Cell line enhanced" "Detected in many" "HDLM-2: 83.8;Karpas-707: 85.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028172, HPA028231, HPA028657" Approved Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA028172: AB_10599602, HPA028231: AB_10601886, HPA028657: AB_10601680" "unprognostic (4.61e-3)" "unprognostic (3.45e-2)" "unprognostic (1.64e-3)" "unprognostic (9.46e-2)" "unprognostic (2.77e-1)" "unprognostic (3.87e-1)" "unprognostic (3.23e-2)" "unprognostic (1.30e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (4.12e-1)" "unprognostic (1.32e-1)" "unprognostic (2.94e-3)" "unprognostic (9.01e-3)" "unprognostic (4.38e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (4.52e-4)" 18.2 7.8 1.4 38.9 1.6 8.8 24.0 1.5 1.9 14.8 3.1 104.7 8.5 24.2 6.2 61.2 22.1 27.7 164.1 1.5 2.0 3.3 2.7 18.1 11.3 3.9 2.4 4.9 85.7 4.2 2.1 6.2 3.1 59.6 15.9 0.8 100.6 43.1 60.9 8.8 18.5 41.0 2.8 12.3 58.9 1.9 2.2 12.2 15.3 41.2 17.3 105.8 14.6 3.2 42.0 0.5 0.2 0.1 28.0 42.2 1.6 21.1 42.9 17.7 22.3 0.0 17.3 0.0 13.6 54.2 4.6 46.0 2.4 1.5 28.4 83.8 3.2 17.5 8.2 0.0 65.2 57.2 19.1 39.1 65.3 52.1 62.4 12.6 0.1 6.3 4.2 85.5 0.5 0.2 1.9 10.0 11.1 0.0 4.3 13.3 9.9 0.8 24.5 0.8 2.3 2.1 0.4 0.1 29.9 7.0 9.0 17.9 3.3 35.0 0.1 6.3 43.5 71.1 30.2 8.7 68.8 23.4 35.3 20.4 3.6 10.9 5.1 2.1 4.4 1.0 4.7 5.0 5.2 0.3 0.4 1.8 72.1 5.7 0.8 0.5 11.9 2.2 1.4 1.6 1.5 1.9 1.5 2.0 3.9 2.4 3.1 2.8 2.2 3.2 20.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 692.7 0.0 0.0 0.0 0.0 0.4 52.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.2 24.7 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.4 27.4 0.0 0.0 0.0 NID1 "entactin, NID" ENSG00000116962 "Nidogen 1" P14543 1 235975830-236065109 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 230.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 362.9;Fibroblasts: 137.6;Hepatic stellate cells: 191.3;Leydig cells: 177.3;Peritubular cells: 125.6;Sertoli cells: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 5.7;intermediate monocyte: 11.2;myeloid DC: 4.4;non-classical monocyte: 7.3" "Group enriched" "Detected in many" 18 "dendritic cells: 4.4;monocytes: 11.2" "Cell line enhanced" "Detected in many" "ASC diff: 1569.3;ASC TERT1: 726.8;HSkMC: 619.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010044 Approved "Secreted to extracellular matrix" NA NA 150000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "CAB010044: AB_2153287" "unprognostic (1.17e-1)" "unprognostic (2.23e-3)" "unprognostic (3.24e-1)" "unprognostic (2.35e-1)" "unprognostic (4.03e-1)" "unprognostic (2.79e-2)" "unprognostic (2.44e-3)" "unprognostic (1.42e-2)" "unprognostic (7.88e-2)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (5.38e-8)" "unprognostic (3.64e-3)" "unprognostic (1.35e-1)" "unprognostic (7.36e-2)" "unprognostic (3.72e-3)" 110.0 35.5 4.1 30.5 6.8 2.6 88.9 3.4 7.4 78.9 8.8 95.9 21.7 87.6 21.3 26.8 88.1 66.2 53.7 3.8 4.3 28.4 76.9 56.4 12.3 4.2 4.0 77.7 18.3 12.6 10.4 230.9 3.9 33.1 21.3 2.0 17.3 40.2 25.1 24.6 61.0 79.8 3.9 38.0 67.0 6.2 5.3 5.4 27.6 26.9 6.1 62.9 53.4 3.8 1.2 5.3 55.3 0.1 1569.3 726.8 106.2 128.1 105.3 78.0 50.7 30.5 39.8 0.0 25.0 191.2 21.3 4.5 36.3 0.4 45.2 0.2 61.3 8.1 5.9 46.3 295.6 0.0 0.7 619.5 5.3 38.2 1.5 30.3 165.7 0.0 0.0 0.0 26.9 0.0 0.1 0.3 56.9 0.0 6.7 0.0 0.1 0.1 0.0 16.6 0.3 47.0 1.0 0.0 10.2 21.3 0.1 52.1 146.5 67.5 44.8 0.1 57.4 0.1 0.0 0.1 0.8 0.0 105.4 0.2 5.7 0.0 0.0 11.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.4 0.1 7.3 0.0 0.0 2.1 4.1 6.8 3.4 7.4 3.8 4.3 4.2 4.0 3.9 3.9 5.3 3.8 48.7 3.2 1.5 18.9 1.7 6.0 1.3 1.5 0.0 0.2 1.2 2.0 24.0 10.0 2.0 0.0 0.0 13.5 0.6 0.0 0.0 0.5 1.4 11.5 362.9 49.4 0.0 5.3 0.6 0.9 10.2 137.6 0.5 9.6 1.3 2.1 191.3 73.4 8.0 3.3 3.3 0.0 10.2 15.1 19.3 5.7 177.3 9.9 17.8 30.0 10.0 2.2 1.0 1.0 0.3 4.3 0.0 125.6 0.0 5.3 0.0 8.6 0.1 0.1 243.3 18.7 92.3 0.8 0.2 0.8 5.3 15.7 2.9 5.7 0.1 7.3 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OSR1 ODD ENSG00000143867 "Odd-skipped related transcription factor 1" Q8TAX0 2 19351485-19358623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 81.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 35.8;Leydig cells: 133.6;Peritubular cells: 45.9;Smooth muscle cells: 21.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.9" "Region enhanced" "Detected in some" "thalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 11 "U-2197: 101.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015525 Uncertain NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA015525: AB_1854822" "unprognostic (1.71e-3)" "unprognostic (1.23e-1)" "unprognostic (6.85e-4)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (8.47e-4)" "unprognostic (2.79e-1)" "unprognostic (1.91e-1)" "unprognostic (6.87e-2)" "unprognostic (3.56e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-3)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" 38.6 2.4 0.4 3.5 0.8 0.0 22.4 0.3 1.7 16.7 1.8 23.1 1.4 10.3 0.3 3.6 8.1 5.9 13.4 1.6 0.0 1.5 0.5 17.0 0.5 0.3 0.1 6.1 2.8 0.2 2.7 3.3 0.2 13.9 2.0 0.0 31.5 3.7 3.0 10.8 11.1 11.3 0.2 0.1 9.7 5.4 3.4 0.6 10.2 3.5 0.1 81.4 12.3 0.0 0.0 2.4 0.1 4.7 3.2 9.2 0.0 6.0 2.8 5.6 2.8 0.0 0.1 0.0 0.0 8.5 2.7 0.0 3.0 1.4 1.4 0.0 0.2 0.0 0.1 3.5 4.0 0.0 0.2 4.6 0.0 5.2 6.9 4.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.1 0.0 3.6 5.0 0.0 0.2 0.0 0.6 1.9 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 1.3 0.4 101.8 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.3 1.7 1.6 0.0 0.3 0.1 0.2 0.2 3.4 0.0 1.2 0.0 0.5 0.0 0.0 4.7 1.0 1.7 0.6 0.0 1.0 6.1 7.2 0.0 1.1 3.7 0.0 0.5 0.1 0.1 0.0 1.3 0.7 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.4 35.8 0.0 0.1 1.3 1.2 0.0 0.0 0.9 0.0 0.0 0.3 4.1 0.0 4.9 3.8 133.6 0.3 3.6 2.8 0.0 0.0 0.0 0.0 0.1 0.4 0.1 45.9 0.0 0.4 0.0 2.9 0.3 0.0 0.0 1.3 21.4 0.4 0.1 0.3 4.1 0.4 0.7 0.8 0.2 1.1 OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108041409-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 210000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Vesicles" "HPA010851: AB_1079533" "prognostic unfavorable (4.36e-4)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (1.72e-3)" "prognostic unfavorable (4.26e-4)" "unprognostic (9.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.34e-6)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" 26.1 19.1 4.7 17.9 5.2 5.7 9.8 5.1 5.8 10.4 33.1 12.2 7.9 13.7 9.0 12.7 9.5 12.5 19.2 5.3 9.2 15.6 13.1 16.2 14.7 6.0 7.6 7.5 5.8 15.3 8.3 14.1 7.9 13.8 11.1 17.6 8.9 16.7 11.8 9.8 9.0 23.3 5.3 18.3 8.5 10.1 7.4 13.7 10.7 11.5 13.5 16.9 7.0 8.3 6.0 17.2 20.1 29.4 59.0 19.0 28.6 42.8 42.7 30.7 50.4 10.0 9.8 13.7 34.4 30.0 82.5 11.1 20.2 14.6 47.0 31.6 15.7 28.9 10.9 12.8 45.6 32.1 64.6 28.1 35.7 37.7 30.0 28.2 15.8 15.2 23.3 48.7 50.3 8.4 7.1 7.3 8.0 7.1 13.0 11.4 29.1 7.5 22.0 15.7 2.2 11.8 34.7 8.7 79.9 26.6 10.0 45.8 19.3 26.7 9.8 59.7 61.4 18.6 34.4 11.9 78.9 21.3 60.3 31.4 20.2 22.8 20.3 29.4 21.5 14.7 16.9 22.3 17.8 8.6 15.6 19.8 29.8 22.0 43.5 12.9 22.6 27.0 4.7 5.2 5.1 5.8 5.3 9.2 6.0 7.6 7.9 5.3 7.4 8.3 28.5 9.6 19.0 26.4 26.0 46.7 19.8 11.7 21.6 28.3 10.0 7.0 24.8 12.8 9.4 12.9 10.4 21.7 32.3 21.9 1.9 12.4 12.0 7.5 15.7 20.7 4.2 4.6 36.6 22.9 33.9 24.4 15.8 9.6 24.1 6.9 26.7 13.2 52.8 28.6 40.1 5.8 6.1 46.5 29.5 5.4 14.3 43.1 151.2 20.6 25.6 23.7 40.2 21.1 36.6 16.8 17.0 28.6 25.0 17.9 7.6 25.5 9.8 17.5 26.3 18.5 29.6 28.0 18.7 12.4 31.1 61.2 29.5 23.7 3.3 16.0 P4HA3 C-P4Halpha(III) ENSG00000149380 "Prolyl 4-hydroxylase subunit alpha 3" Q7Z4N8 11 74235801-74311640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 10.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Early spermatids: 25.6;Erythroid cells: 13.5;Horizontal cells: 18.5;Rod photoreceptor cells: 12.8;Spermatocytes: 13.1;Spermatogonia: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 19.5;fHDF/TERT166: 9.5;HSkMC: 9.1;HUVEC TERT2: 38.2;TIME: 27.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA007897 Approved "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA007897: AB_2156427" "unprognostic (2.74e-2)" "unprognostic (1.37e-4)" "unprognostic (1.31e-3)" "unprognostic (3.19e-2)" "unprognostic (2.54e-4)" "unprognostic (9.65e-3)" "unprognostic (4.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.21e-3)" "unprognostic (1.38e-2)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.34e-9)" "unprognostic (1.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.83e-4)" 1.6 0.7 0.1 3.9 0.0 0.0 0.9 0.1 0.3 1.3 0.3 1.6 0.3 4.5 0.5 0.3 1.2 5.6 0.3 0.0 0.1 1.0 1.3 1.4 0.9 0.1 0.1 1.0 0.2 0.0 3.7 3.9 0.1 6.3 0.7 0.0 0.5 4.3 0.1 0.3 0.4 10.5 0.0 0.1 0.4 1.5 0.1 0.1 2.6 0.1 0.3 5.4 1.7 0.1 0.0 1.4 1.7 0.0 6.2 0.7 0.0 19.5 1.4 1.0 2.1 0.0 0.0 0.0 1.8 9.5 0.7 0.0 0.0 0.3 0.2 0.0 0.1 0.0 1.2 0.0 8.0 0.0 0.0 9.1 0.0 6.5 0.7 1.1 38.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 27.4 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.2 0.4 0.7 0.9 0.0 9.1 0.5 0.1 0.4 0.0 0.2 0.0 14.6 0.2 3.1 0.2 0.0 0.2 25.6 3.8 2.5 3.2 0.0 13.5 2.4 0.0 0.4 5.2 0.0 1.0 0.0 4.3 6.1 0.0 0.4 18.5 3.3 0.2 0.0 0.9 1.1 3.2 0.0 0.3 0.0 6.5 1.6 1.9 3.1 1.5 0.9 0.8 0.2 0.4 0.0 1.1 0.2 0.0 0.7 12.8 0.0 2.1 5.4 13.1 12.2 0.1 0.3 0.1 0.4 1.3 0.2 0.6 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 72.3;Fibroblasts: 56.3;Leydig cells: 37.9;Peritubular cells: 58.6;Sertoli cells: 19.7;Smooth muscle cells: 25.5;Theca cells: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 148.2;ASC diff: 175.0;ASC TERT1: 190.8;BJ hTERT+: 86.8;fHDF/TERT166: 143.3;HHSteC: 129.4;HSkMC: 195.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" 22.2 5.2 2.6 7.9 3.0 0.1 13.5 2.8 3.2 25.3 2.6 12.2 9.3 30.4 11.2 6.4 11.7 22.5 6.5 2.5 4.8 7.1 2.1 7.2 1.7 4.1 5.8 21.0 1.5 2.0 2.4 44.2 3.8 17.5 13.8 2.1 6.5 13.5 2.6 4.1 8.7 18.4 3.2 6.4 6.7 4.5 3.9 3.6 5.1 23.2 1.4 10.8 8.4 3.0 0.0 0.3 148.2 0.0 175.0 190.8 0.1 27.4 86.8 5.0 7.7 0.3 0.0 0.0 0.1 143.3 0.4 0.4 34.2 0.7 2.6 0.2 1.0 0.0 0.0 0.0 129.4 0.0 0.1 195.9 0.3 9.4 3.8 4.7 1.0 0.7 0.0 0.6 2.8 0.0 3.9 0.1 0.3 0.0 2.7 11.7 4.1 0.0 0.0 0.1 0.0 9.6 0.0 0.0 0.2 38.3 0.9 0.0 0.0 69.3 4.2 13.9 0.5 0.2 0.0 0.0 3.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 2.8 3.2 2.5 4.8 4.1 5.8 3.8 3.2 3.9 3.0 3.4 0.0 0.5 1.3 0.0 4.1 0.4 0.1 2.2 2.5 1.1 1.7 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 1.9 72.3 3.0 0.0 0.0 0.2 0.0 0.3 56.3 0.0 1.7 0.0 6.4 2.5 0.0 3.1 0.0 9.0 0.0 0.0 0.0 7.8 1.3 37.9 0.9 1.8 10.3 0.0 6.8 0.0 0.0 0.6 0.0 0.0 58.6 0.1 0.0 0.0 0.1 0.0 0.2 19.7 6.6 25.5 0.6 0.1 1.2 2.6 0.8 0.7 18.5 0.0 0.1 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PDLIM4 RIL ENSG00000131435 "PDZ and LIM domain 4" P50479 5 132257696-132273454 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 315.5;Prostatic glandular cells: 473.0;Skeletal myocytes: 225.2;Urothelial cells: 381.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 91.8;HBEC3-KT: 109.2;HHSteC: 103.7;hTEC/SVTERT24-B: 117.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011912 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Cytosol" "HPA011912: AB_1856277" "unprognostic (1.36e-3)" "unprognostic (1.93e-1)" "unprognostic (1.62e-2)" "unprognostic (8.08e-3)" "unprognostic (4.70e-3)" "unprognostic (2.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.39e-1)" "unprognostic (1.34e-1)" "unprognostic (3.38e-2)" "unprognostic (3.94e-2)" "unprognostic (4.20e-2)" "unprognostic (5.84e-3)" "unprognostic (1.13e-2)" "unprognostic (2.61e-1)" "unprognostic (3.57e-2)" "unprognostic (3.40e-3)" 24.8 6.6 14.5 18.6 13.8 0.7 34.5 17.9 17.8 36.5 20.1 104.9 6.9 90.7 17.7 50.0 48.3 20.5 61.6 15.8 23.8 33.3 1.2 10.5 4.5 27.7 20.5 28.4 6.5 4.9 28.2 8.0 21.3 50.2 4.8 2.6 47.4 28.1 5.4 64.4 27.2 42.9 22.5 6.7 32.2 6.3 17.9 6.6 14.2 2.6 10.1 59.4 39.1 21.7 46.6 0.0 9.7 0.1 13.2 36.7 3.3 12.9 6.3 12.9 4.2 0.0 4.3 0.3 8.6 68.4 65.8 91.8 0.0 109.2 6.1 0.2 5.1 0.0 0.0 2.2 103.7 0.0 0.3 46.5 7.8 117.6 43.7 45.9 74.0 0.0 20.2 0.1 57.6 0.0 0.0 0.3 3.4 0.0 28.1 2.2 66.4 0.2 29.0 0.0 0.0 39.0 29.7 0.0 0.0 7.7 0.1 4.8 47.9 46.3 49.9 48.4 72.9 0.1 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.5 13.8 17.9 17.8 15.8 23.8 27.7 20.5 21.3 22.5 17.9 21.7 10.1 0.0 4.4 5.5 0.7 105.7 315.5 183.8 76.2 0.5 38.2 149.5 6.8 0.0 57.0 14.7 2.1 5.1 0.8 0.6 107.6 121.5 14.2 21.1 81.0 69.8 16.8 0.0 0.7 9.9 14.4 85.1 6.1 17.9 4.5 10.7 21.0 0.3 6.6 0.0 0.6 16.6 61.1 0.3 32.5 15.8 36.4 3.4 165.4 3.7 1.0 17.7 0.0 0.0 0.3 105.7 154.6 27.4 0.0 473.0 5.6 8.9 138.3 0.7 26.3 225.2 53.8 9.9 13.9 47.8 82.8 22.8 4.2 2.0 5.5 381.7 PHETA2 "DKFZp686J07229, FAM109B, IPIP27B, SES2" ENSG00000177096 "PH domain containing endocytic trafficking adaptor 2" Q6ICB4 22 42074248-42079438 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 14.1;Endometrial stromal cells: 10.3;Extravillous trophoblasts: 27.4;Syncytiotrophoblasts: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 20.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;fHDF/TERT166: 33.7;HSkMC: 32.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA000647 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA000647: AB_1078800" "unprognostic (4.96e-2)" "unprognostic (3.28e-2)" "unprognostic (5.90e-2)" "unprognostic (6.66e-3)" "unprognostic (1.56e-2)" "unprognostic (9.61e-3)" "unprognostic (2.40e-1)" "unprognostic (1.19e-1)" "unprognostic (2.31e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (8.80e-2)" "unprognostic (7.52e-2)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (2.81e-2)" "unprognostic (4.03e-2)" 11.1 4.3 2.8 6.6 2.7 4.6 9.7 2.5 2.8 12.2 4.3 11.4 6.0 15.4 2.8 9.6 9.8 8.2 8.5 2.5 2.8 7.1 1.9 9.7 4.1 3.1 2.7 5.2 18.2 4.8 5.8 15.6 2.8 9.9 8.5 0.4 12.7 7.6 2.5 8.3 9.4 12.9 3.1 7.8 13.4 2.5 2.8 2.4 5.8 3.1 4.2 11.3 9.1 2.8 0.1 0.0 0.0 0.2 30.9 36.8 0.2 21.4 17.5 13.0 12.9 22.6 20.5 0.1 13.1 33.7 0.0 3.7 0.1 0.2 6.9 0.0 0.0 0.0 29.1 0.2 17.6 0.0 17.1 32.3 9.5 20.1 2.5 0.0 29.3 0.3 0.2 0.0 14.1 0.4 0.1 0.2 2.4 1.1 0.0 0.2 0.1 0.3 5.9 0.0 0.2 0.2 9.2 0.1 0.1 0.2 14.1 0.0 30.0 0.2 13.8 31.5 0.1 0.5 0.5 0.3 0.0 0.4 24.0 20.0 4.3 1.7 1.3 4.9 0.2 0.5 0.8 1.0 8.4 0.2 0.6 1.2 0.3 0.7 2.8 3.9 0.6 3.2 2.8 2.7 2.5 2.8 2.5 2.8 3.1 2.7 2.8 3.1 2.8 2.8 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 2.4 0.0 0.0 0.0 0.0 0.0 14.1 0.2 0.0 3.9 5.7 0.0 1.1 10.3 3.0 0.0 0.0 0.0 7.0 27.4 6.6 0.0 2.8 0.0 3.8 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 22.2 0.2 3.6 0.0 0.0 PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 204.8;Leydig cells: 205.9;Oligodendrocytes: 67.3;Peritubular cells: 149.7" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cell line enriched" "Detected in some" 6 "JURKAT: 29.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" 57.8 3.5 12.2 3.1 17.7 0.2 66.1 14.3 15.1 140.6 7.9 11.6 1.5 5.7 29.0 10.6 15.0 46.4 127.7 10.1 16.1 1.5 0.7 11.4 2.2 15.3 14.2 3.4 5.6 0.9 8.4 2.4 15.8 31.3 7.9 0.0 14.0 34.2 15.1 51.7 4.5 8.4 13.4 1.3 22.1 14.7 16.4 2.4 23.2 33.6 6.0 116.1 127.6 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.9 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 29.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.8 0.6 19.7 5.7 0.0 1.3 6.4 2.2 0.5 13.5 0.0 0.5 66.1 3.3 12.2 17.7 14.3 15.1 10.1 16.1 15.3 14.2 15.8 13.4 16.4 19.3 10.9 0.0 1.5 3.3 0.7 21.5 0.1 0.0 0.6 0.0 0.4 0.4 4.5 0.0 0.6 1.8 0.0 0.0 0.4 0.0 1.9 0.1 10.8 0.1 0.2 11.0 0.0 0.0 0.1 0.0 0.0 204.8 4.1 0.1 0.0 0.0 10.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 39.6 19.0 205.9 1.9 10.6 3.7 0.0 0.0 0.0 0.0 67.3 0.1 0.0 149.7 0.6 0.1 0.0 0.2 0.0 0.0 0.0 7.7 4.2 2.4 1.3 0.4 18.5 0.1 3.5 0.3 0.0 0.2 PKP2 ENSG00000057294 "Plakophilin 2" Q99959 12 32790755-32896777 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 188.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 393.9;Distal enterocytes: 105.5;Extravillous trophoblasts: 185.9;Undifferentiated cells: 135.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 8.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 198.8;OE19: 72.7;SuSa: 149.0" "Region enriched" "Detected in many" 4 "hippocampal formation: 20.2" "Low region specificity" "Detected in all" "HPA014314, CAB037336, HPA056908" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Cell Junctions" Nucleoplasm "CAB037336: , HPA014314: AB_1855451, HPA056908: AB_2683272" "unprognostic (1.89e-1)" "unprognostic (1.70e-2)" "prognostic favorable (8.55e-4)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.90e-1)" "unprognostic (1.83e-2)" "unprognostic (5.94e-3)" "unprognostic (2.22e-1)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (2.41e-2)" "unprognostic (3.76e-2)" 5.5 2.6 1.6 6.5 2.0 5.8 11.2 3.1 3.8 20.3 8.2 49.8 23.6 5.0 3.9 5.3 73.0 7.4 188.2 8.7 1.0 7.8 25.9 1.3 4.5 1.4 0.3 15.1 16.4 33.6 9.9 20.5 0.6 9.1 45.2 2.6 58.5 6.9 6.0 2.9 26.5 5.5 0.7 2.0 17.8 6.4 1.6 12.4 0.3 1.7 10.6 5.3 3.4 1.6 56.5 10.8 0.4 0.3 0.2 0.0 0.5 0.0 0.0 0.2 0.1 198.8 49.6 0.0 32.9 0.0 7.1 48.8 6.8 43.3 0.0 0.2 15.7 0.3 2.3 52.6 29.5 3.1 0.6 0.2 40.2 0.1 46.2 21.4 1.8 0.1 10.4 15.3 4.8 14.9 0.2 0.4 29.7 72.7 9.5 0.0 23.6 16.8 14.3 26.3 5.9 5.3 2.3 11.4 0.1 149.0 24.7 0.7 0.3 0.1 21.1 0.0 13.5 12.6 0.2 0.4 0.1 0.2 2.6 5.8 0.9 8.1 0.2 1.1 0.6 0.1 0.4 0.3 2.9 0.3 0.5 0.3 0.6 1.0 1.7 0.5 0.4 0.4 1.6 2.0 3.1 3.8 8.7 1.0 1.4 0.3 0.6 0.7 1.6 1.6 0.4 0.0 0.0 0.3 2.2 7.0 48.1 20.7 32.5 3.2 22.1 13.1 393.9 21.5 17.7 1.8 4.2 57.9 0.9 105.5 3.9 12.7 4.0 61.2 11.6 3.7 27.1 2.1 1.3 10.1 185.9 12.9 43.3 52.1 4.5 23.2 5.0 46.0 8.6 1.7 58.8 67.0 26.4 17.0 20.4 1.8 11.8 28.6 10.6 4.7 1.4 14.3 0.0 2.0 1.0 23.6 65.5 2.2 1.6 32.8 30.8 11.0 14.2 1.1 0.0 13.0 9.8 6.9 5.7 12.1 3.3 41.5 2.7 1.0 135.6 28.2 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 93993931-94332823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Astrocytes: 69.5;Distal enterocytes: 79.6;Inhibitory neurons: 83.9;Muller glia cells: 82.7;Oligodendrocyte precursor cells: 123.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.8 2.6 4.5 2.8 4.1 0.2 2.7 3.1 5.6 8.0 7.0 12.6 4.0 9.0 5.3 1.7 4.4 2.5 12.4 3.9 4.7 8.4 0.7 7.3 0.7 3.9 4.8 3.9 14.7 0.8 4.4 2.9 4.0 3.8 7.5 7.3 2.3 5.4 4.1 1.1 5.2 4.2 3.2 6.2 8.3 2.0 5.4 0.5 9.8 6.3 0.6 5.6 5.6 4.2 4.0 6.7 1.8 1.1 0.7 3.2 1.9 2.8 0.6 0.3 0.4 5.3 1.3 0.8 1.3 2.3 1.3 2.6 2.2 0.4 0.6 0.4 2.3 0.5 4.0 0.5 0.0 0.9 0.3 1.8 0.0 1.1 0.0 6.8 0.0 0.4 0.5 0.3 4.2 0.3 0.8 0.9 0.7 7.9 5.0 0.1 3.9 0.2 0.2 10.3 0.9 1.5 3.3 3.6 0.7 4.1 3.5 0.6 0.6 3.0 5.9 2.0 4.4 0.6 0.3 0.4 3.5 1.1 2.2 0.1 0.1 0.0 0.3 0.2 0.2 0.5 0.3 0.2 0.1 0.7 0.5 0.4 0.1 0.2 0.2 0.2 0.1 0.1 4.5 4.1 3.1 5.6 3.9 4.7 3.9 4.8 4.0 3.2 5.4 4.2 8.2 70.5 5.4 69.5 7.0 8.2 9.7 6.8 2.2 12.2 3.6 3.6 34.7 4.3 12.3 0.0 0.0 3.7 2.9 79.6 1.9 1.1 20.7 26.7 18.4 9.7 1.8 0.0 3.1 6.4 2.5 15.3 29.6 10.6 0.0 7.2 4.2 1.6 0.7 6.7 83.9 9.7 4.1 2.4 5.2 5.3 12.2 1.3 7.2 5.6 1.2 82.7 4.1 123.1 2.4 4.2 54.8 23.3 0.9 7.5 11.0 2.5 10.6 18.7 6.6 30.8 37.7 3.7 8.0 1.7 7.4 1.9 4.3 3.7 41.1 10.5 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 359.1;Endometrial stromal cells: 206.7;Hepatic stellate cells: 267.0;Leydig cells: 219.3;Prostatic glandular cells: 182.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 445.7;fHDF/TERT166: 142.8;HMC-1: 235.8;HSkMC: 171.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 172.3 78.1 51.5 42.3 59.9 0.9 140.7 63.7 59.4 88.7 59.6 118.3 47.4 119.5 39.8 42.4 73.4 167.5 117.1 49.9 56.8 104.0 67.7 56.2 32.2 62.1 56.2 29.4 35.6 49.0 27.8 37.6 64.2 254.1 65.8 9.7 32.9 61.3 70.0 57.9 79.1 108.9 62.5 31.1 70.9 21.0 58.6 15.8 112.9 81.5 24.2 128.8 63.8 72.9 9.8 24.4 7.0 14.2 445.7 51.8 9.6 21.8 61.4 11.9 27.9 16.7 17.7 10.2 20.0 142.8 31.9 6.5 25.2 12.6 13.5 6.8 20.1 1.1 9.6 21.3 70.5 2.5 235.8 171.3 25.7 17.6 10.9 23.3 19.9 9.1 0.2 27.0 24.1 6.0 6.8 5.5 15.5 1.1 20.0 2.0 11.7 0.9 46.3 79.8 8.4 5.8 21.5 4.2 13.4 28.8 15.6 1.6 24.0 4.0 6.9 17.8 15.5 16.6 7.4 11.8 15.7 1.3 19.5 0.0 0.4 4.0 1.6 0.5 1.7 6.7 5.3 3.4 2.0 3.3 9.5 7.7 0.3 3.0 0.9 15.0 2.6 1.8 51.5 59.9 63.7 59.4 49.9 56.8 62.1 56.2 64.2 62.5 58.6 72.9 359.1 6.4 9.4 0.0 9.8 0.0 51.0 0.0 10.2 4.0 8.4 45.7 0.0 21.5 5.6 29.5 2.1 3.3 5.4 61.0 5.9 25.2 44.4 10.7 206.7 112.3 1.2 5.7 0.0 28.5 11.1 115.5 11.2 18.5 27.8 4.0 267.0 48.3 12.8 1.7 0.0 20.2 0.0 12.0 0.0 21.0 219.3 8.1 0.0 0.0 4.5 16.6 1.0 0.0 0.0 30.0 24.6 88.4 13.0 182.0 49.4 29.3 2.2 5.6 59.2 89.7 49.7 54.4 17.7 10.0 0.0 4.9 11.3 3.1 12.1 42.8 POGLUT2 "EP58, KDELC1, MGC5302" ENSG00000134901 "Protein O-glucosyltransferase 2" Q6UW63 13 102784281-102798976 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Extravillous trophoblasts: 23.3;Fibroblasts: 3.8;Hofbauer cells: 3.3;Syncytiotrophoblasts: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.9" "Group enriched" "Detected in many" 5 "NK-cells: 3.9;T-cells: 2.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020780, HPA043946, HPA064398" Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 44000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB020780: , HPA043946: AB_2678743, HPA064398: AB_2685256" "unprognostic (1.97e-2)" "unprognostic (2.34e-1)" "unprognostic (3.21e-1)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (6.68e-3)" "prognostic unfavorable (4.81e-4)" "unprognostic (4.34e-3)" "unprognostic (2.75e-2)" "unprognostic (7.26e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.11e-2)" "unprognostic (1.17e-1)" "unprognostic (2.46e-1)" "unprognostic (2.60e-3)" 4.6 2.3 1.5 3.1 2.2 1.6 3.3 2.2 2.4 5.6 1.6 3.5 1.3 11.1 4.3 2.6 4.3 8.1 4.8 1.5 1.5 4.6 7.7 3.4 2.4 1.8 1.7 6.5 1.6 2.8 2.1 12.2 1.9 2.7 2.7 3.4 1.8 4.2 0.8 2.3 2.1 12.5 1.7 3.6 2.4 1.5 1.9 1.9 2.9 2.5 1.9 6.0 3.2 2.7 8.1 6.0 36.8 35.5 37.0 28.5 9.0 21.4 16.4 19.5 33.5 17.1 11.5 0.0 16.7 17.6 10.0 13.3 26.6 10.9 19.5 3.4 22.1 9.8 16.3 18.8 32.1 25.4 34.5 27.0 12.3 14.8 14.2 29.1 43.0 12.3 16.3 0.0 10.5 9.0 11.4 20.8 23.5 11.5 17.9 0.0 26.3 9.5 53.7 0.7 5.5 33.7 21.0 5.6 12.3 30.5 16.1 10.9 13.3 12.8 9.3 14.7 21.6 7.4 14.4 0.0 25.2 0.0 22.6 0.0 0.0 0.0 1.4 0.0 2.4 0.2 0.7 1.1 0.6 0.0 0.2 0.7 0.0 3.9 0.0 0.0 0.9 0.2 1.5 2.2 2.2 2.4 1.5 1.5 1.8 1.7 1.9 1.7 1.9 2.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 23.3 3.8 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 251.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 229.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 3700000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 37.0 20.6 5.3 16.4 5.6 0.2 30.4 6.8 7.0 42.3 12.2 41.4 37.3 31.0 36.5 46.8 14.8 33.5 44.4 5.2 5.8 24.9 28.9 27.0 7.6 6.4 6.3 16.2 30.3 20.9 6.2 48.3 6.2 23.4 49.9 4.9 31.7 24.0 41.2 20.2 32.3 45.2 6.1 7.7 22.4 9.0 6.7 5.8 47.2 33.3 14.2 45.8 28.8 5.8 19.6 16.8 6.4 136.2 229.7 104.6 26.9 54.4 42.3 27.8 56.7 28.1 128.6 0.0 94.2 147.1 83.3 21.9 18.9 68.6 22.1 0.1 33.1 27.8 60.7 32.8 58.9 0.0 14.7 65.8 51.5 32.5 34.0 49.9 58.1 0.0 7.9 0.0 20.1 116.5 0.1 0.3 11.6 120.9 29.0 0.0 14.5 0.0 87.7 67.0 8.5 14.9 106.7 51.1 12.1 77.8 72.0 61.8 64.8 52.9 32.7 18.5 23.9 0.2 0.1 0.4 45.9 0.2 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.6 6.8 7.0 5.2 5.8 6.4 6.3 6.2 6.1 6.7 5.8 214.1 32.1 16.5 6.2 1.6 47.4 52.3 251.7 30.7 16.9 63.9 47.5 46.4 61.5 149.0 73.5 4.2 60.1 0.6 134.0 29.4 201.5 1.7 52.4 94.8 106.5 12.7 0.0 0.8 126.4 65.2 198.2 55.0 50.8 1.3 54.2 80.7 57.8 43.2 0.0 2.2 177.1 207.5 4.2 40.3 4.2 112.5 6.9 32.0 5.6 3.2 2.8 0.0 1.0 0.3 90.3 181.0 100.1 0.6 48.2 189.0 81.7 110.5 4.4 39.5 22.7 87.5 41.6 37.8 118.6 49.3 25.0 3.4 61.2 117.0 81.5 PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 836.8;Excitatory neurons: 225.7;Granulosa cells: 438.3;Oligodendrocytes: 647.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Actin filaments" "HPA024171: AB_1854266, HPA024640: AB_1854265" "unprognostic (5.24e-2)" "unprognostic (8.59e-2)" "unprognostic (1.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.04e-1)" "unprognostic (5.45e-3)" "unprognostic (3.12e-2)" "unprognostic (9.13e-3)" "unprognostic (4.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-3)" "unprognostic (6.98e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" 40.0 11.1 5.1 36.0 12.6 8.3 17.8 8.9 9.9 51.8 15.5 151.0 24.1 222.0 30.5 150.1 52.6 72.5 356.9 5.5 6.5 14.3 8.4 24.8 18.6 17.2 15.3 38.3 7.2 6.2 5.0 34.4 18.0 142.8 64.8 7.6 20.0 198.6 84.1 11.0 30.9 246.4 16.2 30.8 41.5 7.1 9.2 7.7 10.9 80.5 15.1 86.7 23.0 27.3 2.2 4.4 3.3 3.2 4.6 3.3 5.4 1.7 1.7 1.8 1.7 1.9 3.9 2.5 0.8 3.2 4.3 7.0 5.0 2.7 1.9 3.3 3.1 2.5 7.1 1.2 1.1 5.4 2.8 2.6 3.0 2.5 2.6 9.1 1.5 2.8 3.9 2.9 3.1 1.7 4.1 3.4 2.3 2.4 0.9 2.6 8.5 3.7 1.4 8.1 4.0 3.1 3.3 3.9 1.9 4.4 3.4 2.4 1.9 2.5 1.5 1.9 1.5 4.2 4.3 2.7 2.4 4.4 10.2 2.4 1.7 1.5 1.6 1.0 1.4 2.0 1.1 1.0 1.5 2.1 1.3 1.0 16.2 0.7 1.5 1.7 1.7 0.5 5.1 12.6 8.9 9.9 5.5 6.5 17.2 15.3 18.0 16.2 9.2 27.3 12.5 12.8 19.8 181.5 6.0 17.3 49.0 35.6 8.6 59.3 11.1 20.6 836.8 11.5 23.0 12.9 75.0 18.1 8.6 52.9 11.7 10.1 39.2 19.3 16.1 15.2 24.0 5.2 225.7 12.9 8.4 51.4 17.3 7.6 18.9 438.3 16.4 9.6 9.4 26.9 205.0 17.2 63.1 23.5 10.9 13.1 12.2 8.2 8.8 102.1 7.8 10.2 5.2 102.5 647.4 6.3 21.1 51.1 9.6 24.3 12.8 7.1 27.4 30.4 32.9 38.6 162.7 19.3 13.9 7.1 10.9 25.4 10.7 14.2 33.9 28.4 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222424-170305977 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: AB_2676124" "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favorable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 6.7 5.0 2.0 6.9 2.4 2.6 10.4 2.0 3.2 12.7 0.3 12.4 11.6 11.0 8.2 15.1 15.9 11.4 6.9 3.4 1.1 13.5 7.3 16.6 4.6 0.4 0.2 13.6 7.0 13.0 3.1 10.9 0.5 17.3 13.1 6.2 17.5 12.7 6.2 6.9 10.8 11.0 0.2 5.2 34.5 12.5 0.9 10.9 24.5 9.8 10.4 16.1 6.2 1.1 81.6 20.2 20.0 21.6 17.3 23.9 32.2 20.4 29.9 26.4 28.3 29.7 38.6 24.7 65.3 28.8 36.4 37.3 37.9 40.0 44.8 18.2 23.5 22.9 24.3 16.6 27.9 20.9 10.0 21.8 27.5 22.6 35.1 42.8 20.9 13.3 25.8 19.8 27.4 28.0 30.5 8.5 42.3 86.4 22.1 21.8 30.7 41.2 42.3 24.4 31.5 25.8 44.1 57.7 20.0 29.5 63.0 14.5 22.4 27.5 21.1 26.0 34.3 33.9 34.9 35.2 19.8 16.4 11.0 0.0 0.6 0.4 1.1 0.6 1.7 0.9 1.5 2.0 0.8 1.2 1.6 0.9 0.3 2.6 0.5 0.8 1.1 0.7 2.0 2.4 2.0 3.2 3.4 1.1 0.4 0.2 0.5 0.2 0.9 1.1 17.6 73.7 82.1 23.2 5.8 57.1 49.5 39.8 30.7 16.4 29.0 19.7 16.2 24.3 45.3 49.7 14.6 30.2 15.0 29.0 25.4 16.5 8.4 42.0 29.7 20.5 29.3 10.5 77.2 22.0 26.6 32.2 59.7 72.3 8.8 20.4 17.5 17.7 10.0 15.2 55.2 28.3 50.8 18.6 26.8 6.8 23.3 11.6 17.8 22.5 12.7 8.8 6.2 33.2 33.5 55.2 18.6 28.6 29.4 99.4 18.7 20.4 31.9 9.4 19.7 23.7 18.7 15.8 20.6 38.5 63.6 20.7 14.8 14.3 28.5 80.1 PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 351.7;Endometrial stromal cells: 158.6;Fibroblasts: 180.2;Late spermatids: 390.0;Leydig cells: 256.3;Oligodendrocyte precursor cells: 288.5;Smooth muscle cells: 206.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 367.0;ASC TERT1: 290.5;BJ: 109.7;BJ hTERT+: 213.2;HSkMC: 150.6;U-138 MG: 146.0;U-2197: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" 96.3 10.2 14.5 17.7 15.2 0.0 42.9 15.4 13.4 92.0 5.4 5.6 1.1 68.6 20.3 20.1 42.3 34.1 44.2 12.6 26.2 2.3 0.4 21.7 34.6 17.4 18.5 28.2 3.8 7.5 4.9 6.3 16.8 33.5 5.7 0.1 38.5 75.6 51.7 24.1 3.6 52.4 7.9 1.9 3.4 14.2 16.5 18.7 41.6 73.9 36.3 33.0 58.8 15.0 0.0 0.0 2.1 0.0 367.0 290.5 0.1 109.7 213.2 15.0 14.8 0.0 0.1 0.1 0.0 90.2 0.0 0.0 18.5 0.0 4.7 0.0 0.2 0.0 1.6 0.0 1.2 0.0 0.0 150.6 0.0 73.4 0.4 25.7 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.0 0.0 0.1 146.0 2.6 140.4 16.9 0.0 0.0 0.0 77.3 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 15.2 15.4 13.4 12.6 26.2 17.4 18.5 16.8 7.9 16.5 15.0 49.8 0.0 0.5 114.3 0.3 16.3 0.6 0.1 4.0 0.0 1.3 10.2 29.8 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.2 351.7 4.9 158.6 11.4 0.0 0.0 17.4 0.2 0.1 180.2 0.5 3.5 0.0 0.6 0.0 0.0 0.8 0.0 5.5 0.0 0.0 0.0 27.9 390.0 256.3 2.8 14.2 124.6 0.0 0.5 0.0 288.5 0.9 0.7 0.0 104.6 0.4 1.7 0.0 0.1 0.0 0.2 52.6 59.1 206.5 15.4 1.9 1.2 11.8 0.1 2.3 0.6 0.0 1.2 PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Club cells: 34.3;Cytotrophoblasts: 48.0;Respiratory ciliated cells: 76.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 70.2;SH-SY5Y: 215.4;THP-1: 100.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035054 Uncertain Approved "Nucleoplasm,Actin filaments" "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" Nucleoplasm "HPA035054: AB_10603990" "unprognostic (4.30e-2)" "unprognostic (1.04e-2)" "unprognostic (2.55e-1)" "unprognostic (4.41e-2)" "prognostic favorable (2.66e-4)" "prognostic favorable (1.03e-4)" "unprognostic (4.21e-1)" "unprognostic (3.48e-2)" "unprognostic (7.83e-2)" "unprognostic (6.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (9.55e-2)" "unprognostic (1.09e-1)" 0.6 0.5 1.4 1.6 0.9 0.1 2.2 0.6 1.3 14.5 14.4 6.7 2.7 1.9 0.6 3.2 10.5 9.8 0.0 2.7 0.5 0.8 0.6 7.6 0.1 0.5 1.9 1.6 7.7 0.1 0.6 10.6 0.7 1.4 6.4 0.3 2.5 2.0 0.2 5.9 4.8 1.3 0.5 0.0 9.2 10.0 1.2 1.0 0.2 1.2 5.7 3.8 12.6 0.5 5.2 0.2 1.8 0.0 0.2 13.3 0.1 46.0 41.5 9.7 16.1 0.1 18.7 0.0 0.2 70.2 4.9 0.8 31.1 9.5 12.7 0.2 7.2 0.0 3.6 0.0 1.4 0.0 0.2 4.1 17.5 3.4 9.9 31.2 0.1 0.6 0.0 0.0 8.0 0.3 0.5 9.6 2.2 36.4 2.9 0.0 38.7 0.0 0.0 7.0 5.1 215.4 0.0 0.2 3.0 30.9 0.0 100.6 0.0 19.2 2.8 12.2 9.1 1.0 0.1 0.0 1.0 3.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.6 1.3 2.7 0.5 0.5 1.9 0.7 0.5 1.2 0.5 0.3 6.4 4.6 0.7 0.2 8.4 0.8 16.4 2.2 0.6 0.8 0.8 1.4 10.0 34.3 1.8 0.0 48.0 0.0 26.8 0.0 0.4 9.9 19.7 16.8 0.9 5.3 0.0 10.5 10.2 4.5 7.1 17.9 2.6 7.0 3.3 0.0 0.4 3.8 0.0 14.3 2.7 10.2 0.0 4.2 18.3 0.0 0.4 5.4 7.5 0.0 0.0 0.0 0.5 0.2 8.1 12.8 0.0 0.2 0.4 9.4 0.6 76.1 0.2 0.0 0.6 4.9 10.1 13.3 3.6 4.3 11.9 0.7 21.8 5.3 4.7 PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 20.1" "Cell type enhanced" "Detected in many" "Club cells: 14.3;Fibroblasts: 22.7;Inhibitory neurons: 10.4;Langerhans cells: 10.6;Microglial cells: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "ASC TERT1: 271.2;HSkMC: 85.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.89e-3)" "unprognostic (6.03e-2)" "unprognostic (5.63e-2)" "unprognostic (1.45e-3)" "unprognostic (7.61e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "unprognostic (8.46e-4)" "unprognostic (2.21e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-4)" "unprognostic (3.21e-4)" "unprognostic (8.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.21e-3)" 9.9 3.4 0.6 5.7 0.4 0.0 7.2 0.1 1.8 4.6 0.3 2.0 1.0 17.9 2.4 0.9 4.6 6.9 1.7 1.9 2.7 3.9 1.3 2.5 1.2 0.7 0.5 4.6 0.9 0.0 0.2 8.1 1.8 3.1 2.7 0.2 4.7 2.0 2.1 5.2 2.4 16.7 0.4 0.6 1.6 1.4 3.5 0.1 0.8 20.1 4.3 11.9 4.4 0.2 0.0 0.0 1.0 0.0 26.5 271.2 0.0 20.5 20.0 7.0 2.7 0.0 0.0 0.0 0.0 12.4 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 85.7 0.0 1.8 17.6 18.3 0.1 0.0 0.0 0.7 10.9 0.0 0.0 0.0 0.1 0.0 15.9 0.0 0.0 0.0 2.4 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 5.9 8.5 4.7 2.1 1.6 1.1 0.0 0.0 0.5 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 1.8 1.9 2.7 0.7 0.5 1.8 0.4 3.5 0.2 1.2 0.0 8.0 0.3 0.0 6.4 0.0 1.0 0.0 1.2 0.2 0.0 0.4 5.7 14.3 9.2 0.0 0.1 0.0 0.0 3.9 4.2 8.5 0.4 0.6 0.6 0.0 0.0 0.4 0.0 0.0 22.7 0.5 0.1 0.0 0.1 0.0 2.3 0.1 0.0 10.4 0.0 0.0 0.0 10.6 9.3 5.6 0.4 5.4 17.8 0.0 0.3 0.0 0.0 0.2 0.0 1.1 0.4 0.2 0.1 0.0 0.3 6.3 0.0 6.6 7.1 1.4 1.1 0.2 0.1 4.7 0.3 0.5 0.3 0.0 0.0 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1616.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1918.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 84.8 84.9 35.8 52.1 39.4 115.5 53.2 42.7 47.3 81.7 41.1 100.1 67.5 75.2 70.2 178.4 82.3 150.3 244.9 41.5 43.4 73.8 81.7 200.0 16.3 50.0 40.7 196.1 136.3 21.0 60.2 158.9 43.2 92.3 80.9 15.2 105.6 57.5 91.2 58.6 85.7 60.0 44.0 61.9 178.3 172.9 42.6 12.1 31.9 46.0 19.6 174.1 108.7 57.7 441.4 62.0 14.8 181.0 179.1 367.8 712.5 456.5 456.6 381.6 267.1 7.3 137.7 6.8 276.7 367.8 52.6 93.7 17.6 123.5 185.0 26.4 28.0 14.1 33.6 19.4 1918.6 48.6 129.2 197.9 55.5 408.0 484.3 499.9 569.4 32.1 20.2 66.3 255.3 76.4 10.4 89.7 49.4 302.6 174.6 19.7 33.0 11.8 63.1 123.6 51.9 52.6 133.8 179.8 91.9 32.2 33.0 226.3 678.3 473.8 187.5 322.0 392.9 48.3 84.4 12.2 180.9 153.9 146.0 16.2 53.1 20.6 14.0 29.9 10.2 5.4 9.1 9.6 39.2 3.2 8.1 8.0 40.2 16.9 28.6 8.0 11.5 28.6 35.8 39.4 42.7 47.3 41.5 43.4 50.0 40.7 43.2 44.0 42.6 57.7 36.6 57.7 101.6 8.5 7.7 13.8 27.4 81.2 7.4 11.5 86.2 47.9 48.3 51.5 112.5 71.7 25.0 19.5 10.7 138.1 0.0 230.4 49.2 49.2 19.4 41.7 46.2 6.9 17.2 130.1 1616.7 78.0 136.6 80.4 25.4 27.1 89.3 4.3 68.6 6.7 17.0 185.7 132.2 45.2 35.3 20.1 177.7 48.9 44.4 8.4 49.7 53.5 10.3 24.6 23.9 249.8 165.6 71.1 12.8 35.7 9.0 9.1 47.8 6.7 32.9 13.6 31.3 30.2 32.7 10.2 9.9 154.3 13.9 13.9 89.9 68.0 RARRES1 "LXNL, TIG1" ENSG00000118849 "Retinoic acid receptor responder 1" P49788 3 158696892-158732489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 221.9;fallopian tube: 206.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 217.1;Club cells: 621.4;Prostatic glandular cells: 312.9;Urothelial cells: 737.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 93.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 10 "CAPAN-2: 1319.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003892 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "Endoplasmic reticulum" "HPA003892: AB_1856079" "unprognostic (5.76e-3)" "unprognostic (2.13e-1)" "unprognostic (8.85e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.09e-2)" "unprognostic (8.93e-2)" "unprognostic (3.86e-1)" "unprognostic (7.16e-3)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.88e-6)" "unprognostic (3.49e-1)" "unprognostic (1.33e-1)" "unprognostic (7.73e-2)" "unprognostic (1.15e-1)" 221.9 21.3 1.0 65.1 1.5 0.6 44.6 1.5 1.7 74.6 11.3 31.7 5.1 25.9 27.0 11.3 206.4 19.7 81.5 1.5 0.8 25.1 4.2 52.7 18.9 0.6 0.4 60.5 10.0 0.2 27.7 3.5 0.4 78.6 36.2 0.9 165.3 37.2 5.6 8.3 38.5 51.2 0.4 2.7 23.7 4.5 1.0 1.8 20.4 2.8 6.2 92.1 32.2 1.4 19.2 6.9 0.2 1.0 4.0 12.6 0.3 1.8 5.7 1.0 1.4 1.4 1319.3 0.0 1.2 0.9 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.1 12.0 0.0 0.0 131.3 0.0 0.5 0.0 8.9 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.7 5.8 0.0 0.0 0.0 0.1 0.3 22.9 0.5 1.7 16.7 1.3 0.3 0.0 1.9 2.3 1.3 1.1 0.0 4.6 0.0 0.0 0.0 0.0 1.5 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.0 1.5 1.5 1.7 1.5 0.8 0.6 0.4 0.4 0.4 1.0 1.4 5.2 0.0 0.6 2.3 0.9 0.5 217.1 92.7 11.4 0.4 99.7 35.6 0.9 11.5 621.4 14.7 0.0 2.9 1.6 59.0 0.0 10.5 29.5 14.4 98.4 18.1 37.5 3.6 14.2 4.7 0.8 101.3 1.1 16.9 29.9 0.3 31.8 6.0 10.8 0.0 10.6 102.3 40.7 1.6 1.7 33.1 10.8 11.0 5.4 1.9 0.0 4.2 0.0 4.5 7.6 2.3 106.1 1.2 1.2 312.9 140.7 19.7 149.3 0.7 0.0 7.7 46.7 3.8 0.7 7.8 0.4 11.4 3.3 0.1 88.3 737.7 RBPMS2 ENSG00000166831 "RNA binding protein, mRNA processing factor 2" Q6ZRY4 15 64739891-64775589 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 300.8;intestine: 147.2" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 215.3" "Cancer enriched" "Detected in all" 4 "testis cancer: 37.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.0;AN3-CA: 55.4;HEL: 86.2;NTERA-2: 76.4;SuSa: 86.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" "unprognostic (1.07e-2)" "unprognostic (6.79e-2)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.61e-1)" "unprognostic (4.51e-2)" "unprognostic (6.41e-2)" "unprognostic (5.86e-2)" "unprognostic (2.21e-2)" "unprognostic (4.47e-2)" "prognostic favorable (1.48e-4)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" 20.0 4.9 5.2 6.7 6.1 1.6 12.5 2.7 4.7 18.4 14.7 147.2 6.0 53.1 7.5 20.3 30.8 9.9 300.8 3.7 4.3 17.8 13.9 7.6 1.0 3.3 5.0 10.6 2.7 16.5 4.1 7.7 3.0 27.5 8.1 2.0 2.5 45.8 5.6 4.9 30.2 37.6 2.9 4.4 51.9 6.4 12.6 2.5 13.8 4.9 0.6 94.0 14.4 3.2 0.0 6.3 39.0 55.4 0.0 0.0 5.9 1.2 0.2 7.0 1.6 4.9 0.5 0.0 5.2 1.1 6.5 0.0 28.8 0.0 2.6 0.0 9.0 86.2 9.5 9.9 3.7 0.0 0.7 0.1 0.0 4.4 0.0 1.5 0.7 1.9 0.5 0.0 0.5 2.9 0.0 0.3 76.4 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 13.5 8.5 0.1 1.6 86.5 7.9 0.3 0.0 0.0 28.4 3.7 3.7 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 5.2 6.1 2.7 4.7 3.7 4.3 3.3 5.0 3.0 2.9 12.6 3.2 3.1 0.0 0.0 0.0 1.1 0.8 0.3 0.0 0.6 0.3 0.5 0.5 215.3 0.0 0.0 3.7 0.0 0.6 2.0 0.0 9.8 0.4 4.7 0.4 3.4 6.4 0.0 7.4 0.3 1.6 1.1 11.1 5.1 0.7 0.0 0.9 2.9 8.5 0.3 0.0 0.2 0.0 0.0 1.3 1.3 1.0 3.7 10.4 1.8 1.0 0.2 3.3 9.2 0.0 0.0 1.2 0.0 6.4 0.0 1.5 0.0 31.0 0.0 1.7 46.0 1.7 51.0 0.8 14.1 0.3 1.1 3.1 0.7 1.0 0.0 0.2 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 REXO2 "CGI-114, DKFZP566E144, SFN" ENSG00000076043 "RNA exonuclease 2" Q9Y3B8 11 114439435-114450279 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038450, HPA038451" Enhanced Supported "Nucleoli,Focal adhesion sites,Mitochondria" NA NA 340000 "Cluster 6: Non-specific - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "Nucleoli, Focal adhesion sites" "HPA038450: AB_10672516, HPA038451: AB_10697391" "unprognostic (3.26e-3)" "unprognostic (2.36e-2)" "prognostic favorable (6.51e-4)" "unprognostic (6.84e-3)" "unprognostic (5.80e-3)" "unprognostic (1.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.78e-1)" "unprognostic (8.18e-3)" "unprognostic (2.49e-2)" "unprognostic (2.17e-3)" "unprognostic (1.02e-1)" "unprognostic (1.73e-2)" "unprognostic (6.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.69e-2)" "prognostic unfavorable (6.70e-4)" 51.1 57.2 23.5 40.3 25.9 55.0 57.1 26.3 31.5 73.4 28.6 80.4 24.3 71.5 46.5 65.8 38.1 47.8 140.3 24.0 29.5 102.5 50.2 42.0 32.5 30.3 28.1 69.0 45.5 154.5 32.5 56.9 29.7 72.5 47.2 9.2 115.3 58.0 40.8 50.5 33.1 106.7 26.6 44.8 65.4 53.5 25.7 30.4 36.5 40.5 37.1 68.3 64.4 29.9 159.3 92.7 32.1 88.4 254.6 268.7 81.9 266.3 192.9 122.6 155.4 244.9 261.2 88.8 258.2 220.8 185.4 97.4 74.1 219.5 201.5 86.9 61.3 98.1 136.0 144.7 339.2 72.3 29.5 190.8 206.0 157.4 163.7 214.1 223.1 84.7 183.9 48.6 278.5 38.7 49.4 84.0 102.3 119.1 160.3 45.7 112.1 317.1 177.0 126.9 59.8 38.5 122.7 86.7 110.8 134.8 184.9 35.6 231.4 162.5 194.2 124.0 161.6 39.7 52.4 146.3 111.3 165.2 89.7 64.3 14.0 21.3 32.2 19.2 37.2 37.6 47.9 41.1 18.8 29.2 43.0 35.1 3.5 45.2 20.6 70.1 75.3 29.1 23.5 25.9 26.3 31.5 24.0 29.5 30.3 28.1 29.7 26.6 25.7 29.9 82.9 105.8 56.4 20.9 42.3 138.9 146.5 189.1 88.2 14.9 99.2 100.6 370.0 47.1 126.5 95.6 2.1 171.6 55.3 27.2 277.8 126.6 83.6 75.3 110.8 98.4 80.9 315.2 20.0 70.7 188.5 176.8 48.4 85.2 31.8 40.1 89.6 80.0 98.2 5.0 17.4 82.9 89.5 21.0 56.7 48.1 210.6 33.9 241.9 15.9 41.9 36.5 29.9 25.1 33.5 110.0 33.7 176.8 103.8 199.6 26.7 371.4 126.5 8.3 52.6 90.6 177.0 237.3 82.1 119.9 162.7 269.1 47.5 120.6 72.4 130.4 RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 41.0;Astrocytes: 176.0;Endothelial cells: 72.5;Hepatic stellate cells: 41.4;Microglial cells: 35.6;Oligodendrocyte precursor cells: 43.2;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 63.8;HUVEC TERT2: 375.4;TIME: 100.9;WM-115: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" 19.6 3.3 12.5 8.5 14.6 0.1 17.4 10.8 16.9 12.9 8.5 14.2 7.5 27.9 17.3 15.5 18.5 25.3 17.9 14.0 11.1 11.7 4.2 21.5 9.6 10.9 11.0 14.2 4.4 3.5 6.4 9.3 11.0 11.8 10.7 5.5 8.4 13.8 7.9 7.6 9.8 31.4 8.3 12.6 9.3 2.8 14.5 3.1 13.8 13.4 4.9 19.7 9.4 13.0 0.0 0.0 63.8 0.0 0.0 0.0 0.0 10.6 42.6 3.6 6.2 0.0 0.0 0.0 5.9 0.8 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.3 0.0 0.1 8.0 35.8 375.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 5.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 14.6 1.1 0.1 0.0 100.9 0.1 1.1 0.8 6.1 0.0 0.0 0.0 0.0 0.0 106.5 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.5 14.6 10.8 16.9 14.0 11.1 10.9 11.0 11.0 8.3 14.5 13.0 41.0 0.0 1.3 176.0 0.3 5.9 0.3 0.1 0.0 0.3 1.2 5.2 3.8 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.5 0.3 6.7 72.5 0.0 0.0 11.1 0.9 0.0 31.0 0.0 0.3 0.0 0.5 41.4 0.5 0.1 0.0 2.2 0.0 0.0 1.9 7.7 1.6 11.8 1.0 3.6 35.6 0.0 11.1 0.0 43.2 0.4 0.1 0.0 16.1 2.5 0.6 0.0 0.0 0.0 0.4 6.6 34.6 17.0 0.1 0.4 0.9 4.8 0.1 0.6 6.9 0.0 1.4 RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 18.5;Endothelial cells: 42.4;Fibroblasts: 73.0;Hepatic stellate cells: 26.4;Inhibitory neurons: 17.8;Leydig cells: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 21.9;BJ hTERT+: 3.6;hTERT-RPE1: 6.3;U-138 MG: 4.6;U-87 MG: 4.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 33: Fibroblasts - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" 30.9 15.1 2.1 16.1 2.4 0.0 12.4 3.3 4.9 13.8 0.0 7.4 2.2 51.4 28.4 5.4 25.3 11.1 0.9 8.5 1.5 4.0 6.5 5.1 3.7 1.6 1.4 3.6 1.6 0.1 3.1 35.4 0.3 6.3 6.6 0.1 5.4 20.0 39.8 2.8 10.3 48.1 0.0 1.8 13.3 1.0 1.0 2.4 3.6 5.0 1.4 8.6 7.1 0.9 0.0 21.9 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 6.3 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.6 1.8 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 3.3 4.9 8.5 1.5 1.6 1.4 0.3 0.0 1.0 0.9 3.6 0.0 0.0 0.7 0.1 0.9 0.1 0.0 0.6 1.5 0.2 0.9 0.5 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.4 12.3 0.3 18.5 42.4 0.0 0.0 5.9 0.0 1.1 73.0 5.1 0.3 0.0 0.0 26.4 0.4 1.6 0.0 17.8 0.0 0.0 1.0 0.8 2.2 27.4 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.2 6.6 2.1 3.5 0.1 0.4 0.4 0.1 1.6 0.1 0.1 0.0 0.2 RSU1 "FLJ31034, RSP-1" ENSG00000148484 "Ras suppressor protein 1" Q15404 10 16590611-16817463 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025927 Uncertain Approved Vesicles NA NA 33000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA025927: AB_10610420" "unprognostic (7.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.08e-1)" "unprognostic (4.89e-1)" "unprognostic (9.56e-3)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (1.99e-1)" "unprognostic (3.83e-2)" "unprognostic (3.72e-2)" "unprognostic (3.30e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.48e-1)" "unprognostic (4.53e-2)" 35.6 14.2 8.8 22.0 8.9 27.9 25.4 8.8 10.1 21.2 10.1 27.8 12.0 30.3 19.9 27.7 19.2 19.7 25.1 8.7 10.1 19.4 16.7 27.7 22.3 10.5 9.4 21.8 21.2 14.1 3.9 23.2 9.8 17.9 23.8 9.9 14.5 27.0 15.8 15.9 13.7 41.8 8.6 20.4 15.6 5.5 10.4 18.1 18.7 13.8 22.3 24.0 18.0 9.6 27.3 18.6 15.0 88.5 78.4 80.3 18.3 66.3 28.2 45.1 48.6 17.3 25.0 27.0 10.5 91.2 24.1 23.9 18.3 34.7 48.3 40.6 14.6 85.2 11.1 16.7 34.5 13.1 47.8 40.0 36.0 43.3 13.7 40.9 47.8 27.8 14.0 18.2 61.6 17.6 30.5 23.5 15.7 39.6 10.5 19.6 20.3 18.4 44.0 10.0 5.9 11.6 33.1 21.6 33.6 26.8 7.6 34.4 58.8 38.4 13.3 48.5 34.6 15.9 20.6 23.3 51.0 37.1 16.9 33.0 20.9 22.8 24.7 26.0 28.0 16.6 28.1 26.7 34.7 17.9 20.5 25.8 14.6 31.3 25.5 25.9 36.0 48.5 8.8 8.9 8.8 10.1 8.7 10.1 10.5 9.4 9.8 8.6 10.4 9.6 111.1 35.3 24.5 26.4 29.9 36.7 30.3 74.0 12.0 1.7 22.5 36.2 41.2 27.1 48.3 42.3 2.1 131.9 41.6 57.0 68.4 72.1 80.5 20.7 47.2 69.6 7.2 74.7 52.8 119.2 83.0 52.8 28.5 24.8 34.2 20.5 64.2 32.7 121.7 3.3 34.7 19.0 52.9 61.1 80.7 163.3 39.4 106.2 60.5 52.5 92.3 5.8 66.9 45.8 51.7 81.2 16.8 68.4 36.7 17.4 14.9 58.3 48.8 17.9 65.7 32.4 136.1 3.9 22.6 34.1 42.8 96.2 46.8 35.9 27.2 24.9 RTL8B "CXX1c, FAM127C, MAR8B, SIRH4" ENSG00000212747 "Retrotransposon Gag like 8B" Q17RB0 X 135020513-135022542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 103.8;Distal tubular cells: 29.4;Extravillous trophoblasts: 31.2;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 52.9;U-2197: 67.7" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "prognostic unfavorable (2.41e-5)" "unprognostic (1.13e-2)" "unprognostic (8.78e-3)" "unprognostic (1.08e-3)" "unprognostic (1.76e-1)" "unprognostic (2.86e-2)" "unprognostic (3.32e-3)" "unprognostic (4.34e-1)" "unprognostic (5.25e-2)" "unprognostic (1.62e-3)" "unprognostic (1.50e-2)" "unprognostic (2.33e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (2.56e-1)" "unprognostic (2.02e-1)" "unprognostic (1.80e-2)" 15.9 22.2 6.7 4.3 7.7 0.2 14.4 7.2 7.9 18.4 4.1 18.3 2.4 21.4 6.3 19.8 15.6 6.8 19.2 6.0 7.8 12.4 2.5 12.4 2.1 7.8 7.1 14.6 6.6 8.2 13.4 9.2 7.4 15.3 3.2 15.0 13.7 12.3 8.6 14.4 7.5 12.1 7.3 7.6 11.7 5.2 7.3 1.5 10.7 7.5 2.9 18.7 17.2 7.3 0.0 6.0 19.6 16.0 14.4 9.3 0.1 21.8 30.1 17.2 18.3 10.7 0.8 0.0 52.9 32.0 5.3 0.9 3.8 2.8 12.8 0.1 10.7 2.7 19.1 0.0 23.6 0.0 0.0 40.7 2.4 13.1 0.0 0.6 12.5 0.0 0.0 0.0 29.4 26.2 0.0 1.6 5.6 0.0 25.1 0.0 22.4 0.1 20.1 4.9 13.3 31.9 16.9 10.6 9.0 5.2 8.9 11.6 16.9 0.1 9.3 67.7 0.6 0.0 0.0 0.1 26.0 0.0 10.9 0.0 1.6 0.0 0.0 1.0 0.0 0.0 0.1 0.2 0.9 0.0 0.5 0.3 0.2 0.0 1.6 0.6 0.0 0.8 6.7 7.7 7.2 7.9 6.0 7.8 7.8 7.1 7.4 7.3 7.3 7.3 14.4 12.8 7.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 13.5 14.0 0.0 0.0 3.7 11.0 0.0 103.8 0.4 0.0 29.4 12.6 0.0 8.2 16.1 9.7 0.0 0.0 0.0 9.6 31.2 6.9 0.0 14.3 0.0 4.8 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 17.0 0.7 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 30.9 0.4 8.9 0.0 0.0 SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 90.0" "Group enriched" "Detected in some" 4 "Fibroblasts: 174.0;Leydig cells: 135.8;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 211 "dendritic cells: 21.1" "Cell line enriched" "Detected in some" 20 "ASC diff: 229.1" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" HPA024661 Approved NA NA 1400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA024661: AB_1853902" "unprognostic (2.76e-2)" "unprognostic (7.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.53e-2)" "unprognostic (2.34e-2)" "unprognostic (4.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.13e-2)" "unprognostic (2.40e-1)" "unprognostic (4.21e-2)" "unprognostic (1.10e-1)" "unprognostic (7.09e-6)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" 60.5 4.0 0.4 7.2 0.8 0.0 34.6 0.8 1.8 16.6 4.9 38.5 8.7 2.9 8.2 21.1 23.7 22.5 90.0 0.6 0.4 1.0 4.1 20.2 2.4 0.3 0.2 11.2 2.4 0.2 5.4 12.5 0.2 8.4 33.7 0.3 29.0 3.3 15.1 31.1 26.3 6.5 0.5 3.3 27.3 11.6 0.2 3.2 21.1 34.5 2.1 77.1 36.8 0.3 0.0 7.9 0.0 0.0 229.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 11.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.1 0.4 0.8 0.8 1.8 0.6 0.4 0.3 0.2 0.2 0.5 0.2 0.3 7.1 0.0 0.0 0.0 0.1 6.5 0.1 0.0 0.6 0.0 0.5 0.6 4.6 0.0 0.0 0.0 0.0 0.1 6.7 0.2 0.0 0.0 1.5 0.7 27.9 2.4 0.0 0.0 0.3 0.0 0.4 174.0 4.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 2.9 0.0 0.0 0.0 17.0 4.6 135.8 1.3 7.2 5.6 0.0 1.9 0.0 0.0 0.2 0.0 0.0 11.3 0.8 0.1 0.0 0.0 0.0 0.1 0.0 7.4 3.6 0.7 1.1 0.9 6.0 0.1 1.1 44.5 0.3 0.1 SELE "CD62E, ELAM, ELAM1, ESEL" ENSG00000007908 "Selectin E" P16581 1 169722640-169764705 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 56.1" "Cell type enriched" "Detected in some" 4 "Endothelial cells: 379.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HUVEC TERT2: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" CAB002143 Enhanced NA NA 8140000 180000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002143: AB_563608" "unprognostic (2.39e-1)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.09e-2)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (1.59e-1)" "unprognostic (2.94e-1)" "unprognostic (3.63e-1)" "unprognostic (3.88e-1)" "unprognostic (9.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.56e-2)" "unprognostic (8.13e-3)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.55e-1)" 29.6 5.5 1.2 12.6 0.8 0.5 12.0 0.5 1.7 4.1 4.1 4.2 0.7 5.3 0.5 4.0 23.8 10.7 8.0 0.8 1.6 7.6 6.9 10.3 3.0 1.8 1.2 3.3 1.2 12.5 4.0 1.4 1.7 27.7 2.6 0.3 3.1 3.8 0.8 5.5 2.3 18.7 1.3 0.0 5.2 2.4 2.9 8.4 13.8 1.0 3.6 56.1 5.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.5 1.7 0.8 1.6 1.8 1.2 1.7 1.3 2.9 1.1 34.6 0.0 3.8 0.0 0.0 46.1 1.1 0.0 1.2 0.0 0.5 0.3 4.0 1.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.3 379.5 0.0 0.0 0.1 0.0 0.0 12.7 0.0 0.2 1.3 0.0 3.9 8.5 0.0 0.0 0.0 0.0 0.0 0.0 81.9 3.0 0.0 0.9 46.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.3 4.1 0.2 0.0 1.2 47.7 0.0 3.4 0.1 0.1 2.5 SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 14.7;Endothelial cells: 51.8;Hepatic stellate cells: 33.9;Macrophages: 10.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 8.3;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.3;T-cells: 8.8" "Group enriched" "Detected in some" 38 "EFO-21: 36.0;HEL: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" 11.3 2.3 0.2 11.9 0.6 2.2 10.6 0.0 0.6 8.9 3.7 3.3 5.1 6.4 4.1 5.1 6.7 9.5 6.7 0.3 0.0 5.6 2.5 12.6 7.0 0.2 0.2 1.8 1.2 3.1 2.2 6.3 0.2 6.1 4.1 0.0 2.7 5.7 1.0 3.6 4.8 14.2 0.1 1.0 2.8 0.7 0.7 2.6 4.0 1.8 12.6 14.4 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.4 0.6 0.0 0.2 0.0 1.1 0.5 0.2 0.0 0.1 0.2 0.1 2.1 0.3 0.0 0.1 8.8 7.8 0.2 0.6 0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.1 0.7 0.2 14.7 0.0 3.6 0.3 0.4 3.7 0.1 0.0 0.6 0.0 0.2 0.1 1.9 1.5 0.0 1.8 0.0 2.6 0.1 0.0 0.0 0.0 2.0 0.1 0.1 51.8 0.0 5.2 0.5 0.2 0.0 1.5 0.0 0.0 0.0 0.0 33.9 0.4 0.2 0.0 0.2 0.0 0.0 1.5 3.6 0.1 0.3 10.1 3.6 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.1 3.4 4.1 0.5 0.0 0.0 0.3 SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1875.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 697.8;Cytotrophoblasts: 795.6;Fibroblasts: 951.9;Hepatocytes: 765.0;Leydig cells: 1818.0;Peritubular cells: 1045.7" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enhanced" "Detected in many" "hippocampal formation: 85.4" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1454.4" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1454.4" "Group enriched" "Detected in many" 4 "ASC diff: 1232.0;ASC TERT1: 956.3;Hep G2: 606.0;HHSteC: 410.6;HSkMC: 1313.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" NA NA 9290000000 44000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" 535.5 57.5 5.7 124.2 9.6 11.9 490.2 17.9 28.0 558.7 1875.2 131.3 41.9 358.2 90.2 109.3 557.4 559.7 376.5 85.4 1.1 35.1 974.8 158.9 133.5 0.1 5.1 408.3 207.6 11.2 62.4 311.6 1.3 202.8 52.0 61.4 124.6 105.8 434.8 162.9 131.7 221.7 2.8 133.2 124.7 277.7 25.4 106.2 193.1 465.5 117.7 323.4 273.5 7.0 0.5 3.7 2.8 2.0 1232.0 956.3 20.4 56.8 49.8 0.6 0.0 9.7 0.5 2.3 1.9 71.8 0.3 3.2 86.0 4.4 0.0 0.6 46.0 1.0 1.2 606.0 410.6 1.1 1.1 1313.4 6.9 0.9 1.1 11.4 0.6 4.2 117.5 0.4 63.2 0.2 7.0 7.2 30.7 0.3 1.0 2.9 219.9 1.6 0.1 6.0 1.9 42.2 0.7 0.7 57.0 3.4 6.7 184.2 2.0 0.5 17.6 14.1 1.2 0.7 2.4 28.1 1.7 0.6 0.8 0.1 12.0 1.1 0.6 4.4 0.4 9.0 0.7 0.9 79.8 5.2 2.0 5.5 1.7 1.3 0.2 1454.4 0.8 14.2 5.7 9.6 17.9 28.0 85.4 1.1 0.1 5.1 1.3 2.8 25.4 7.0 59.0 3.2 10.4 0.3 10.8 95.0 238.0 697.8 27.9 59.3 6.7 71.2 12.1 11.5 167.7 1.8 223.1 795.6 226.1 0.0 0.0 0.3 11.2 12.5 372.4 26.2 0.0 19.2 5.3 24.5 98.7 951.9 11.2 6.7 22.9 1.7 28.2 765.0 151.6 3.3 2.6 0.0 366.2 60.4 262.6 53.0 1818.0 79.0 108.5 9.4 79.0 11.6 1.0 0.5 2.0 6.8 0.1 1045.7 7.0 155.5 0.2 27.3 105.5 39.1 19.7 193.3 202.8 12.7 8.7 4.5 78.6 534.8 14.3 10.2 0.3 47.7 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SH3D19 "DKFZp434D0215, EBP, Eve-1, EVE1, Kryn, SH3P19" ENSG00000109686 "SH3 domain containing 19" Q5HYK7 4 151102751-151325605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 263.9;Oligodendrocytes: 360.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 190.3;ASC TERT1: 161.0;HSkMC: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016424, HPA058562" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA016424: AB_1856814, HPA058562: AB_2683758" "unprognostic (1.09e-1)" "unprognostic (6.14e-2)" "unprognostic (1.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (5.09e-1)" "unprognostic (7.37e-2)" "unprognostic (1.48e-1)" "unprognostic (6.40e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.64e-2)" 70.8 15.7 9.8 12.8 14.9 0.2 31.5 6.0 9.6 22.5 104.9 44.2 44.4 23.2 10.7 40.8 23.7 63.7 64.1 6.8 11.6 27.2 49.9 36.2 5.1 8.8 10.3 42.9 15.2 19.9 5.0 27.9 8.8 27.1 48.3 12.8 17.3 40.5 17.7 30.0 49.0 41.4 5.1 7.4 22.6 12.4 11.5 3.9 25.1 33.8 7.9 33.3 20.6 18.6 26.3 19.2 12.1 9.5 190.3 161.0 26.0 31.8 34.0 13.9 14.4 24.9 31.6 0.0 12.5 29.9 22.7 19.2 12.8 36.6 13.5 0.1 10.1 0.0 22.2 26.7 46.0 0.1 0.1 129.1 27.6 20.9 32.0 23.9 81.9 0.0 0.0 0.1 36.9 10.9 0.0 0.4 24.3 40.3 27.6 0.0 0.9 0.4 17.3 18.3 0.9 16.3 22.7 23.0 18.5 24.7 7.5 0.1 59.9 43.6 15.6 19.5 12.9 0.1 0.0 0.1 22.6 0.1 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.8 14.9 6.0 9.6 6.8 11.6 8.8 10.3 8.8 5.1 11.5 18.6 36.7 22.4 32.5 8.1 2.9 28.6 14.1 12.3 18.8 6.6 20.5 25.0 88.5 34.3 29.2 16.5 14.6 25.9 5.0 103.5 5.9 11.9 4.4 17.6 38.1 29.1 18.6 7.0 55.8 15.4 20.7 77.9 38.7 13.7 21.5 37.5 21.8 46.4 7.4 6.7 30.0 35.6 10.2 4.6 20.2 6.7 62.1 4.8 26.6 74.0 1.2 20.8 5.2 263.9 360.1 21.3 55.9 48.2 3.2 41.5 88.2 27.2 52.4 11.0 13.1 46.0 26.3 2.9 6.0 16.7 38.5 27.2 5.5 20.3 54.0 41.2 SLC12A4 KCC1 ENSG00000124067 "Solute carrier family 12 member 4" Q9UP95 16 67943474-67969601 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041138 Approved Approved Endosomes NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Endosomes "HPA041138: AB_10794544" "unprognostic (5.07e-2)" "unprognostic (6.18e-2)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (9.28e-2)" "unprognostic (1.48e-2)" "unprognostic (4.28e-2)" "unprognostic (3.26e-3)" "unprognostic (9.58e-2)" "unprognostic (1.55e-1)" "unprognostic (2.01e-2)" "unprognostic (1.81e-2)" "prognostic favorable (2.25e-6)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (7.64e-2)" "unprognostic (2.26e-1)" 30.2 29.1 11.0 11.8 13.6 5.0 28.9 15.2 10.9 33.5 60.6 32.4 7.2 34.0 8.6 13.0 27.5 14.7 46.1 10.8 13.7 20.2 17.4 34.7 9.4 17.5 17.0 23.9 19.1 23.2 13.0 27.2 14.8 30.4 5.8 3.7 18.0 26.8 20.9 24.3 16.5 27.3 14.9 15.4 18.6 12.3 14.8 12.0 35.4 16.8 5.7 27.3 23.2 15.3 13.4 17.5 13.3 25.3 43.0 37.5 71.6 39.9 41.1 33.5 29.1 35.2 20.8 4.7 19.3 55.3 18.7 23.7 6.2 49.2 25.2 4.8 5.3 3.4 23.4 38.9 48.7 0.4 16.0 41.6 31.6 45.3 16.3 39.1 21.0 8.6 10.9 3.8 46.6 2.1 5.2 13.3 10.0 3.8 9.2 5.3 25.1 4.4 18.5 11.4 0.1 8.0 76.1 4.5 6.8 32.8 35.8 5.4 28.8 47.6 33.4 21.4 17.6 23.2 6.3 8.0 27.9 3.6 42.1 7.1 2.5 1.2 0.8 3.3 0.5 0.3 0.5 0.5 1.4 0.5 0.4 0.4 0.9 1.9 2.4 0.7 0.9 1.1 11.0 13.6 15.2 10.9 10.8 13.7 17.5 17.0 14.8 14.9 14.8 15.3 25.8 16.0 9.1 10.4 2.4 10.1 15.8 13.3 17.6 1.2 3.9 6.6 26.9 2.8 10.6 14.7 0.0 30.1 2.2 0.5 0.0 13.7 3.5 4.0 10.7 15.6 0.0 2.5 0.2 8.3 16.4 19.5 3.1 3.2 1.3 10.9 12.1 10.3 8.0 0.0 0.3 0.1 24.4 5.3 4.3 2.7 19.9 4.2 10.6 4.7 11.4 20.5 3.1 2.0 0.7 15.5 0.1 36.5 10.8 16.9 0.1 5.3 8.3 1.0 39.5 17.3 23.1 12.0 9.1 2.4 5.3 63.5 2.6 13.9 0.2 12.9 SMAD6 "HsT17432, MADH6, MADH7" ENSG00000137834 "SMAD family member 6" O43541 15 66702236-66782849 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 30.1;lung: 27.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 25.1;Hepatic stellate cells: 91.4;Microglial cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 29.8;HaCaT: 18.2;HeLa: 28.6;U-2197: 17.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061917 Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA061917: AB_2684637" "unprognostic (1.20e-1)" "unprognostic (7.43e-3)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (3.02e-1)" "unprognostic (3.50e-3)" "unprognostic (9.59e-2)" "unprognostic (4.50e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (1.10e-3)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (1.55e-3)" "unprognostic (4.30e-2)" "unprognostic (1.33e-1)" "prognostic favorable (5.45e-5)" 9.5 2.6 5.2 1.6 4.9 0.1 7.6 4.9 4.3 6.8 8.6 3.7 1.9 6.2 0.6 2.1 5.4 1.4 30.1 3.4 4.1 8.9 6.7 27.9 0.5 7.6 5.4 5.9 2.7 1.1 3.4 7.4 5.8 7.0 1.1 0.9 2.1 3.5 1.6 2.4 3.9 0.9 4.4 2.6 5.5 1.8 6.8 0.4 15.5 1.5 0.2 8.0 5.7 4.6 1.3 10.2 1.6 3.5 6.0 1.6 9.4 7.2 0.1 1.1 0.1 2.0 4.6 0.7 29.8 6.1 0.9 18.2 2.2 0.0 0.2 2.3 8.4 16.1 28.6 1.7 0.7 0.1 1.2 2.0 0.0 0.1 0.0 3.4 1.3 5.1 1.4 1.0 0.5 2.0 0.1 4.4 3.0 10.5 3.8 0.0 1.8 2.2 3.4 8.1 3.6 1.6 3.9 4.3 0.8 5.9 1.4 2.9 6.2 4.3 5.5 17.6 1.4 0.5 1.8 0.3 3.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 4.9 4.9 4.3 3.4 4.1 7.6 5.4 5.8 4.4 6.8 4.6 19.8 12.8 6.0 5.2 0.9 0.8 1.2 2.1 0.6 0.6 0.9 1.1 4.9 4.3 3.0 1.8 2.1 0.8 0.1 4.3 3.9 4.7 3.4 8.3 5.5 25.1 0.0 0.0 0.3 5.8 0.9 4.9 5.1 6.5 4.5 5.9 91.4 4.0 1.7 0.0 0.3 2.1 0.0 10.0 0.3 1.4 2.8 1.2 0.0 57.1 0.7 10.2 0.0 0.5 0.4 8.4 1.5 8.2 0.0 1.3 2.1 1.9 0.1 0.6 0.0 0.9 1.5 0.2 3.2 0.4 0.1 0.8 0.4 0.1 5.5 0.4 SMAD7 "MADH7, MADH8" ENSG00000101665 "SMAD family member 7" O15105 18 48919853-48952052 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 54.5;Distal enterocytes: 56.6;Hepatic stellate cells: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.1;eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026212, HPA028897" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "CAB026212: , HPA028897: AB_10600811" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (8.15e-2)" "unprognostic (5.35e-1)" "unprognostic (2.76e-1)" "unprognostic (6.02e-2)" "unprognostic (2.37e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-1)" "unprognostic (2.09e-1)" "unprognostic (1.91e-1)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-2)" "unprognostic (4.44e-1)" 17.9 5.9 7.1 8.6 7.3 17.8 14.5 12.0 7.3 17.4 9.6 12.7 10.3 11.2 2.9 4.8 8.2 10.2 46.1 5.4 5.1 11.6 8.6 21.9 5.8 10.9 8.7 7.5 5.3 12.3 6.6 18.9 8.5 11.3 11.9 3.2 6.3 8.6 10.7 8.3 15.0 9.3 10.0 5.9 12.5 1.3 7.9 3.7 16.6 6.7 5.2 13.3 12.2 8.4 3.7 2.8 2.8 8.3 14.3 5.0 21.1 18.6 7.1 6.5 3.1 1.0 5.3 0.3 32.2 13.1 6.0 19.2 6.1 5.8 3.6 38.4 9.4 0.3 10.5 6.9 2.1 6.9 18.6 5.1 4.8 7.8 7.8 32.2 1.1 0.6 6.6 25.9 9.1 1.2 0.0 1.9 17.3 27.7 1.1 2.1 2.5 9.0 9.1 4.2 4.8 10.3 8.0 3.5 6.6 21.2 3.3 5.6 17.3 18.5 9.9 5.3 16.5 13.4 7.1 2.0 8.1 4.9 3.1 4.1 0.1 5.6 0.8 0.5 0.6 0.1 0.8 0.7 0.1 0.0 0.2 0.5 0.0 1.7 0.1 0.0 1.2 0.2 7.1 7.3 12.0 7.3 5.4 5.1 10.9 8.7 8.5 10.0 7.9 8.4 30.4 54.5 9.4 3.9 7.0 12.9 3.5 7.2 14.2 6.1 14.7 10.3 9.7 1.5 11.2 11.0 6.2 9.9 43.7 56.6 9.8 14.4 0.2 43.2 30.5 25.0 12.7 0.0 6.5 13.9 3.3 15.5 8.2 45.9 18.9 4.0 71.4 3.1 8.9 0.0 5.0 19.1 2.0 23.3 8.9 1.1 1.5 14.7 0.0 19.7 8.2 1.4 11.3 5.5 16.3 31.5 17.3 3.4 13.8 3.0 28.7 7.1 3.3 2.5 6.6 11.3 14.1 0.1 0.6 14.2 11.8 12.9 25.2 1.3 12.4 2.6 SNX9 "SDP1, SH3PX1, SH3PXD3A" ENSG00000130340 "Sorting nexin 9" Q9Y5X1 6 157700387-157945077 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 251.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 146.6;GAMG: 145.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031410, HPA057203" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA031410: AB_10603339, HPA057203: AB_2683368" "unprognostic (1.63e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (1.39e-1)" "unprognostic (8.09e-2)" "unprognostic (8.09e-2)" "unprognostic (1.40e-2)" "unprognostic (4.06e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (7.93e-2)" "unprognostic (4.99e-3)" "unprognostic (4.45e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.95e-4)" "unprognostic (2.14e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" 57.9 25.2 19.2 25.7 20.6 14.3 41.4 21.2 20.9 38.8 20.6 34.2 33.2 41.8 20.8 57.8 26.2 46.9 33.2 18.8 19.9 26.2 39.0 21.0 24.2 22.2 21.1 28.0 28.5 37.7 13.4 48.5 21.8 31.0 29.5 2.7 35.1 41.7 24.4 30.4 35.6 41.2 20.9 18.4 37.5 11.0 20.7 13.9 29.8 34.2 21.7 49.8 33.7 23.0 26.0 19.1 18.9 22.1 96.6 78.6 37.7 46.3 146.6 36.4 48.9 16.6 27.6 0.0 25.0 85.6 145.8 18.7 22.7 36.3 21.1 23.9 23.4 17.7 25.7 23.9 48.6 7.6 31.6 51.1 33.9 37.8 37.1 63.9 49.8 23.3 80.9 0.0 15.8 17.2 0.0 15.6 14.4 18.7 21.3 0.0 17.9 32.7 59.7 15.9 11.8 20.9 34.1 16.4 90.5 16.2 6.8 20.0 41.7 41.3 16.6 128.8 30.4 0.0 0.0 0.0 84.8 6.4 25.4 0.0 0.7 0.1 0.4 2.1 1.5 3.2 0.7 0.6 1.4 2.4 5.3 1.2 0.0 0.1 6.8 10.0 2.2 0.6 19.2 20.6 21.2 20.9 18.8 19.9 22.2 21.1 21.8 20.9 20.7 23.0 71.5 0.0 1.1 40.5 102.6 43.3 109.7 17.3 30.1 15.6 28.7 18.4 28.4 28.6 19.0 9.2 0.0 40.6 37.6 97.7 21.5 57.5 73.4 112.8 53.0 57.9 15.7 17.7 105.4 55.9 41.1 83.0 70.3 251.1 12.0 16.4 37.1 34.3 41.6 3.3 90.4 43.0 8.2 59.0 74.2 26.8 44.7 84.3 21.4 48.7 39.5 11.1 7.2 100.5 161.2 107.0 108.9 46.6 14.9 127.5 52.5 46.2 14.3 1.8 39.5 43.6 49.6 21.9 15.4 22.9 29.8 109.9 48.8 9.1 29.7 137.0 STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 49.9;granulocytes: 80.7;monocytes: 33.0" "Cell line enhanced" "Detected in all" "HDLM-2: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038623, HPA051324" Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA038623: AB_10967059, HPA051324: AB_2681442" "unprognostic (2.14e-2)" "unprognostic (1.01e-1)" "unprognostic (9.94e-2)" "unprognostic (2.43e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (5.82e-4)" "unprognostic (1.16e-1)" "unprognostic (3.41e-2)" "unprognostic (1.09e-1)" "unprognostic (1.95e-1)" "unprognostic (5.05e-2)" "unprognostic (1.05e-2)" 23.9 11.6 6.5 21.6 8.6 17.2 14.0 6.9 11.1 17.2 6.4 28.9 12.9 27.1 7.5 22.7 15.1 25.7 44.9 6.7 8.6 12.9 12.5 12.3 12.4 8.1 7.5 7.0 12.3 26.9 7.2 15.7 8.4 20.2 21.2 6.6 13.8 15.0 8.8 10.8 14.3 33.3 7.6 12.0 18.6 11.2 9.5 17.8 9.2 16.4 14.8 24.6 15.5 6.8 12.0 15.7 40.1 17.7 18.6 12.4 30.8 7.7 11.5 4.8 6.5 19.8 8.5 29.3 17.7 6.4 13.6 21.9 19.0 13.4 7.2 157.8 17.3 18.7 17.5 10.0 15.5 43.7 19.7 14.7 13.3 17.6 21.7 29.3 38.1 36.8 21.2 21.1 9.7 8.3 28.5 46.3 49.6 31.2 25.4 10.6 47.8 22.4 6.8 22.0 6.7 22.3 33.1 19.9 13.3 38.6 9.8 14.0 16.4 15.5 13.9 23.7 20.3 7.7 8.1 29.1 8.0 19.9 6.7 16.3 33.0 60.8 10.0 28.4 7.0 11.6 7.7 9.8 49.9 9.3 9.4 7.6 80.7 11.6 22.4 21.2 10.8 14.7 6.5 8.6 6.9 11.1 6.7 8.6 8.1 7.5 8.4 7.6 9.5 6.8 24.4 19.2 16.2 32.7 20.8 35.4 36.3 88.2 22.2 12.7 16.2 14.7 76.0 10.0 33.7 9.2 2.1 11.0 21.7 33.6 9.8 49.8 23.1 12.5 15.3 26.2 19.2 15.4 57.2 40.1 9.1 19.7 15.3 14.9 17.7 10.9 24.3 14.5 28.8 10.1 37.5 33.8 18.3 36.4 73.7 5.9 6.5 45.7 21.4 37.5 46.2 8.1 14.4 42.3 16.0 70.5 26.3 12.0 22.8 24.8 9.2 16.2 11.9 7.9 19.7 8.6 41.1 12.1 13.4 20.5 32.0 27.8 15.7 9.7 23.0 42.0 TBCD ENSG00000141556 "Tubulin folding cofactor D" Q9BTW9 17 82752065-82945914 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, GTPase activation" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 204.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045200 Approved NA NA 6200 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA045200: AB_10969134" "unprognostic (4.15e-1)" "unprognostic (1.01e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-3)" "unprognostic (2.72e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.39e-5)" "unprognostic (3.41e-3)" "unprognostic (9.03e-3)" "unprognostic (5.35e-2)" "unprognostic (1.75e-3)" "unprognostic (6.40e-2)" "unprognostic (1.16e-1)" "unprognostic (4.96e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" 34.3 23.9 17.6 22.2 19.0 23.2 31.7 12.1 17.6 32.7 17.9 22.9 15.5 27.1 24.7 28.9 26.8 33.0 39.3 18.3 14.4 26.6 25.7 26.3 24.0 16.9 15.2 25.7 28.4 26.3 26.5 27.5 17.1 28.1 14.8 11.3 70.0 18.7 25.1 23.3 23.3 21.6 11.1 34.6 30.6 24.5 14.7 51.7 36.7 18.5 21.1 26.1 26.6 16.9 63.1 61.9 63.9 89.8 36.9 40.5 65.3 37.0 24.1 40.5 28.2 34.9 16.6 36.7 34.3 44.3 52.0 64.8 144.6 36.0 34.5 46.7 56.7 85.8 52.8 46.1 23.9 30.8 60.9 33.8 26.2 30.5 13.6 28.4 122.6 68.5 47.2 14.9 35.1 70.9 204.4 19.4 30.1 32.2 45.0 107.9 71.7 23.1 28.5 59.2 61.5 70.9 40.0 70.0 24.6 39.7 52.7 18.7 52.8 75.9 56.8 48.2 60.4 21.1 17.2 40.7 47.3 37.7 29.5 21.3 17.7 9.6 23.4 41.3 28.6 1.3 21.0 24.7 15.4 1.1 8.6 10.4 3.7 18.2 51.7 3.0 16.8 16.9 17.6 19.0 12.1 17.6 18.3 14.4 16.9 15.2 17.1 11.1 14.7 16.9 50.3 19.2 43.2 31.0 9.1 6.8 10.7 9.3 8.6 15.6 16.0 13.8 7.0 11.5 15.7 12.9 12.5 31.8 14.8 11.1 11.7 12.0 11.5 17.8 11.7 34.3 16.2 24.4 48.5 15.2 27.9 18.3 27.5 27.5 38.1 30.5 16.1 26.4 25.7 13.5 43.9 11.4 32.6 15.7 7.0 20.8 15.2 14.2 19.6 31.9 10.8 7.5 17.5 19.6 45.4 9.7 4.7 18.8 16.7 9.9 6.0 16.0 14.9 13.8 6.6 15.7 10.6 15.9 21.8 15.8 10.1 49.7 29.3 21.0 15.3 12.1 TEAD2 "ETF, TEF-4, TEF4" ENSG00000074219 "TEA domain transcription factor 2" Q15562 19 49340595-49362457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 51.1;Early spermatids: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 1.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Cell line enhanced" "Detected in many" "AF22: 135.3;AN3-CA: 147.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066292, HPA069963" Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA066292: AB_2685651, HPA069963: AB_2686222" "unprognostic (2.69e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (8.66e-4)" "unprognostic (2.91e-1)" "unprognostic (4.47e-3)" "unprognostic (1.11e-1)" "unprognostic (3.96e-3)" "unprognostic (1.24e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" 32.8 17.8 7.5 15.4 7.1 0.2 31.6 6.6 7.9 41.8 16.2 50.4 7.6 39.6 12.4 11.0 34.2 15.5 55.5 7.5 6.8 34.5 11.9 35.7 9.0 8.7 8.3 33.5 26.8 19.4 9.2 17.7 7.7 26.5 11.2 3.4 18.5 22.7 12.9 10.7 18.5 38.4 7.6 14.8 31.3 26.6 8.3 3.1 16.9 22.1 7.3 27.2 24.4 6.6 12.5 28.6 135.3 147.6 14.2 20.8 24.3 22.8 23.9 25.6 29.7 2.3 6.8 1.2 29.6 38.5 13.1 13.9 37.5 7.7 14.1 0.1 17.5 0.0 27.2 19.3 24.6 0.1 0.3 24.8 17.8 17.4 8.4 50.6 92.1 0.1 22.0 0.0 36.1 15.3 0.0 0.2 45.4 35.2 36.2 0.0 40.8 0.2 23.3 0.2 0.2 82.0 38.1 5.6 10.1 46.1 40.5 3.5 55.0 45.9 28.1 9.9 1.8 0.1 0.1 4.8 1.7 0.6 18.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 7.1 6.6 7.9 7.5 6.8 8.7 8.3 7.7 7.6 8.3 6.6 26.1 3.2 3.2 0.0 3.8 3.3 6.9 5.9 8.6 0.4 21.1 9.5 1.0 8.6 3.4 12.9 0.0 0.6 0.4 1.3 1.9 51.1 76.6 7.3 20.7 29.5 7.1 3.2 0.1 26.2 23.7 15.0 9.7 6.5 0.0 14.7 21.4 2.8 0.6 0.0 0.1 6.6 8.2 0.9 3.6 29.6 15.2 0.7 5.4 1.9 0.0 15.9 0.0 0.0 0.1 22.7 4.9 22.2 0.1 7.2 0.1 0.2 1.2 0.4 32.9 7.6 28.7 2.1 2.4 2.0 1.6 1.2 0.5 4.4 6.8 2.8 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 432.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.5;Cytotrophoblasts: 311.1;Ductal cells: 226.7;Endometrial stromal cells: 459.1;Hepatic stellate cells: 408.0;Hepatocytes: 205.7;Pancreatic endocrine cells: 326.5;Syncytiotrophoblasts: 374.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 1546.7;EFO-21: 505.5;hTERT-RPE1: 994.3;HUVEC TERT2: 695.3;TIME: 924.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Yes No 1700000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 105.9 45.1 23.0 68.4 22.3 3.2 30.3 22.9 29.5 432.0 53.0 30.6 29.8 266.3 28.3 37.3 217.7 127.7 394.9 21.4 23.0 76.7 244.1 288.5 18.0 25.4 22.5 40.6 25.6 19.3 95.9 234.3 26.0 88.7 20.8 2.1 9.8 56.6 63.9 4.0 63.7 159.0 24.4 32.7 62.3 3.9 30.6 15.4 36.3 33.4 10.3 154.2 87.8 24.8 65.0 47.5 0.2 1.8 47.3 5.1 24.0 95.5 45.2 0.7 1.8 78.4 1546.7 0.1 505.5 1.0 105.4 1.7 0.1 221.7 3.4 0.7 0.2 10.3 2.6 35.0 191.9 0.0 0.5 5.2 0.4 40.2 0.3 994.3 695.3 0.0 21.4 0.1 16.0 0.3 0.0 0.6 0.8 0.9 4.6 0.0 0.1 0.3 69.0 0.0 0.0 1.3 224.4 0.2 7.6 31.6 2.2 0.6 924.2 1.6 57.6 7.8 46.3 0.0 0.6 0.8 60.7 0.1 18.4 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 22.3 22.9 29.5 21.4 23.0 25.4 22.5 26.0 24.4 30.6 24.8 58.0 9.6 18.3 0.0 7.4 0.5 10.4 41.0 0.6 0.0 8.5 8.8 204.5 31.5 55.3 14.7 2.1 311.1 0.1 11.7 3.9 226.7 3.2 16.7 459.1 183.8 0.0 74.5 0.1 145.7 38.6 37.7 0.5 13.1 2.5 2.8 408.0 205.7 54.4 0.0 0.1 1.8 6.1 23.7 2.1 5.0 1.2 35.5 0.0 28.1 6.5 0.4 0.0 0.0 0.3 326.5 1.1 6.0 0.0 68.6 63.0 27.6 23.6 0.5 0.0 5.2 49.1 0.4 4.0 0.9 0.0 374.2 3.9 2.1 3.3 26.4 TMEM117 DKFZp434K2435 ENSG00000139173 "Transmembrane protein 117" Q9H0C3 12 43835967-44389762 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 65.6;Excitatory neurons: 220.2;Inhibitory neurons: 190.3;Microglial cells: 80.6;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046223 Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046223: AB_10960636" "unprognostic (1.37e-2)" "unprognostic (2.99e-1)" "unprognostic (4.32e-1)" "unprognostic (2.39e-2)" "unprognostic (3.57e-2)" "unprognostic (7.08e-2)" "unprognostic (3.07e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (2.89e-1)" "unprognostic (6.26e-2)" "unprognostic (1.99e-3)" "unprognostic (1.74e-2)" "unprognostic (2.30e-2)" "unprognostic (2.65e-1)" "unprognostic (9.20e-3)" "unprognostic (3.80e-1)" 1.8 1.9 0.9 1.2 1.4 0.1 2.7 1.5 2.1 3.8 8.8 3.4 6.0 4.0 2.6 5.8 2.3 3.5 4.2 1.3 1.3 2.2 2.1 1.1 1.4 2.4 1.5 2.5 3.7 4.1 1.7 3.0 2.8 3.5 3.5 2.3 2.1 5.2 3.3 4.0 4.2 4.0 1.4 0.7 2.1 2.4 1.3 0.9 2.3 3.3 2.3 4.1 3.8 2.6 1.2 0.4 4.0 6.7 4.5 9.6 0.1 12.6 6.2 2.3 2.7 10.0 4.3 4.5 0.9 9.0 0.6 6.4 2.6 2.8 1.7 1.9 7.4 1.2 2.5 4.0 1.3 1.8 4.7 5.0 9.9 1.3 0.7 9.2 0.4 0.5 2.2 1.9 4.4 1.1 0.0 1.1 0.8 0.0 2.4 3.0 4.5 1.8 4.5 2.7 0.6 6.1 4.8 1.5 10.2 1.6 0.3 4.7 1.5 3.4 1.1 1.8 3.3 3.4 3.9 2.6 1.7 2.0 1.2 0.0 0.0 0.0 1.2 0.0 1.7 1.0 0.3 1.2 0.0 0.9 0.5 0.6 0.0 0.4 0.0 0.1 0.2 0.4 0.9 1.4 1.5 2.1 1.3 1.3 2.4 1.5 2.8 1.4 1.3 2.6 3.2 0.0 1.3 65.6 8.4 6.5 4.8 3.4 9.6 3.9 2.4 2.8 5.4 2.8 2.5 7.3 4.2 15.0 2.8 6.9 3.9 2.8 25.8 3.9 5.5 2.1 0.0 1.7 220.2 3.0 2.7 3.8 18.3 6.0 2.5 6.0 4.2 2.7 5.6 5.0 190.3 4.2 12.2 3.8 2.5 9.5 6.2 2.1 12.4 80.6 0.1 3.4 3.1 123.1 152.4 2.5 19.2 6.4 11.2 2.1 13.8 1.3 2.7 5.2 0.0 2.2 3.8 1.4 5.5 17.7 12.1 11.5 5.1 2.3 5.0 4.9 TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 86.9;smooth muscle: 84.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 10.3;Inhibitory neurons: 14.4;Langerhans cells: 10.8;Smooth muscle cells: 9.3;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;ASC TERT1: 87.8;HUVEC TERT2: 78.7;LHCN-M2: 74.5;TIME: 105.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA077484: AB_2732347" "unprognostic (1.38e-1)" "unprognostic (6.22e-2)" "unprognostic (1.12e-3)" "unprognostic (6.63e-2)" "unprognostic (2.54e-1)" "unprognostic (1.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-2)" "unprognostic (4.21e-2)" "unprognostic (4.70e-3)" "unprognostic (6.54e-2)" "unprognostic (9.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (3.51e-4)" 9.4 3.8 9.2 7.1 8.3 0.8 5.7 3.5 8.2 13.7 4.3 8.6 1.6 86.9 6.0 20.4 45.6 6.2 6.3 15.3 6.6 2.7 2.4 15.5 3.9 5.5 8.5 15.9 2.4 0.8 3.0 2.0 4.8 6.8 8.6 0.3 3.9 5.4 4.7 23.1 7.9 84.8 4.3 19.9 5.8 4.4 6.6 0.9 5.4 3.5 3.2 18.6 15.1 5.6 0.1 0.4 0.1 0.2 35.0 87.8 0.4 0.3 0.1 1.0 1.6 0.1 1.0 0.1 1.5 5.0 11.2 0.1 1.2 0.8 0.4 0.1 0.7 0.0 2.4 5.9 9.1 0.3 1.9 32.5 7.1 6.7 26.8 5.8 78.7 0.1 0.1 0.1 74.5 0.9 0.0 0.6 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.1 0.1 0.1 0.9 0.5 0.6 105.5 8.0 0.5 26.5 2.3 0.4 0.0 0.1 16.7 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.6 0.3 0.2 0.2 0.0 0.0 9.2 8.3 3.5 8.2 15.3 6.6 5.5 8.5 4.8 4.3 6.6 5.6 1.2 0.0 0.5 4.6 0.0 3.3 1.1 0.4 0.0 0.1 0.2 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.3 2.3 1.7 3.9 10.3 0.0 4.5 0.4 0.0 5.8 0.0 0.1 0.0 7.1 1.8 0.3 2.9 0.0 14.4 3.3 2.0 2.9 10.8 0.7 9.0 3.5 1.8 1.0 0.6 0.1 0.0 1.0 2.6 0.1 1.5 5.3 0.1 0.4 0.0 0.1 1.3 0.2 6.6 1.6 9.3 23.7 0.8 0.3 8.4 0.0 0.1 0.1 1.5 0.5 TNMD "BRICD4, ChM1L, myodulin, TEM, tendin" ENSG00000000005 Tenomodulin Q9H2S6 X 100584936-100599885 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 21.1;breast: 12.9;seminal vesicle: 26.1" "Cell type enriched" "Detected in some" 7 "Adipocytes: 73.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HAP1: 6.9;NTERA-2: 16.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA034961, HPA055634" Uncertain NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034961: AB_10670285, HPA055634: AB_2682868" "unprognostic (3.60e-2)" "unprognostic (9.84e-3)" "unprognostic (3.19e-2)" "unprognostic (7.77e-3)" "unprognostic (2.42e-1)" "unprognostic (2.15e-1)" "unprognostic (2.36e-2)" "unprognostic (1.37e-1)" "unprognostic (9.40e-2)" "unprognostic (9.60e-4)" "unprognostic (6.82e-2)" "unprognostic (5.67e-2)" "unprognostic (1.48e-1)" 21.1 0.2 0.2 0.6 0.1 0.0 12.9 0.0 0.2 0.5 1.1 0.8 0.1 0.3 0.2 0.3 0.3 0.5 1.0 0.2 0.5 0.8 0.0 0.0 0.1 0.5 0.5 2.1 0.1 0.0 0.0 2.4 0.3 1.3 0.5 0.0 0.5 26.1 3.3 3.2 0.5 0.7 0.1 0.2 0.1 0.1 0.4 0.4 0.2 5.8 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.2 0.5 0.5 0.5 0.3 0.1 0.4 0.1 73.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.4 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 3.9 0.0 0.0 0.0 0.1 5.3 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 3.2 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.7 0.5 9.3 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.7 3.2 0.0 0.1 0.0 1.0 0.0 0.3 0.7 0.6 0.0 TRIOBP "DFNB28, HRIHFB2122, KIAA1662, TAP68, Tara" ENSG00000100106 "TRIO and F-actin binding protein" Q9H2D6 22 37697048-37776556 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003747, HPA019769" Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA003747: AB_1858328, HPA019769: AB_1858329" "unprognostic (2.94e-1)" "prognostic favorable (4.29e-4)" "unprognostic (2.79e-1)" "unprognostic (4.57e-2)" "unprognostic (8.22e-2)" "unprognostic (7.44e-3)" "unprognostic (3.77e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (5.56e-2)" "unprognostic (2.40e-1)" "unprognostic (1.99e-1)" "unprognostic (4.38e-3)" "unprognostic (1.31e-1)" "unprognostic (2.81e-1)" "unprognostic (3.20e-2)" "unprognostic (1.67e-2)" 56.3 46.5 15.4 27.3 16.6 25.7 50.8 14.7 14.9 73.1 22.1 70.6 23.9 71.8 12.8 78.5 66.1 27.8 74.6 12.8 13.2 37.2 21.6 51.6 17.4 20.0 17.2 55.7 32.7 31.1 16.9 44.2 16.5 45.3 17.0 4.8 44.3 33.3 24.3 32.0 38.0 31.0 16.6 53.1 53.6 26.1 16.9 16.7 48.2 14.3 12.5 66.5 65.7 17.3 65.9 53.1 33.2 26.4 73.1 118.1 47.5 113.0 111.9 57.7 42.1 11.8 44.8 24.5 30.4 69.6 31.6 52.7 9.2 63.7 18.1 39.6 29.1 6.8 41.6 22.4 75.5 32.1 28.9 47.1 29.8 52.0 24.5 125.3 71.9 20.6 6.4 34.6 45.5 39.3 14.4 23.1 20.2 65.4 63.2 25.1 23.9 17.2 41.0 52.8 16.2 25.4 50.9 46.5 59.7 32.8 25.4 23.0 151.9 87.2 38.6 60.6 27.0 30.4 9.1 15.4 82.7 13.0 104.3 7.7 7.6 12.2 1.8 7.5 0.6 1.3 1.5 1.8 4.1 2.4 1.2 1.8 18.2 1.9 12.5 1.9 2.5 2.0 15.4 16.6 14.7 14.9 12.8 13.2 20.0 17.2 16.5 16.6 16.9 17.3 102.0 19.2 29.7 17.9 10.7 6.2 48.3 18.3 18.8 22.8 40.1 45.1 65.2 62.9 23.3 58.8 2.1 105.7 14.7 63.8 15.6 42.7 30.3 32.6 107.0 91.6 22.9 28.2 4.7 51.6 34.2 65.5 58.1 34.2 6.3 128.1 124.6 17.1 42.7 16.8 4.6 52.1 6.1 56.0 7.5 10.6 113.1 31.2 14.2 27.2 32.0 29.6 8.2 7.5 14.0 62.8 46.9 92.2 9.5 41.9 24.8 15.8 23.9 7.3 52.6 17.7 31.8 49.8 23.4 57.2 6.1 116.0 12.7 22.5 40.6 57.9 TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 83.5" "Group enriched" "Detected in many" 6 "Adipocytes: 72.2;Cardiomyocytes: 22.3;Early spermatids: 29.7;Endothelial cells: 51.8;Hepatic stellate cells: 70.3;Proximal tubular cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 36.7;CAPAN-2: 61.5;GAMG: 35.2;HDLM-2: 48.7;NTERA-2: 33.0;RH-30: 38.4;SCLC-21H: 31.9;SH-SY5Y: 36.2;SuSa: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (8.53e-3)" "unprognostic (3.48e-2)" "unprognostic (6.30e-2)" "unprognostic (8.64e-2)" "unprognostic (7.17e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (6.78e-3)" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-2)" 22.2 46.1 5.8 10.4 4.3 1.2 10.0 30.5 8.2 14.4 3.6 47.9 6.7 46.7 3.6 21.0 20.8 13.3 83.5 26.1 4.6 14.5 4.9 22.4 7.7 5.1 10.4 7.4 1.6 3.9 5.4 30.2 4.9 15.8 9.9 1.0 3.3 41.4 14.7 6.3 16.4 46.6 8.9 14.1 16.6 4.0 10.8 4.0 14.8 19.9 4.2 23.1 10.2 2.3 0.0 0.6 36.7 0.5 0.0 0.0 0.0 0.6 0.5 2.3 0.1 7.3 61.5 0.0 16.4 1.0 35.2 0.0 6.6 0.2 0.6 48.7 2.4 0.2 5.0 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.0 0.0 14.3 0.2 1.1 0.0 0.1 0.0 0.0 0.1 33.0 0.1 1.0 0.1 38.4 0.2 0.0 0.0 31.9 36.2 0.4 0.1 0.1 99.8 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 1.6 1.0 0.0 0.0 1.6 0.1 0.0 0.8 0.2 1.1 0.5 0.0 0.0 1.3 0.2 0.3 0.5 0.0 0.0 0.3 1.7 5.8 4.3 30.5 8.2 26.1 4.6 5.1 10.4 4.9 8.9 10.8 2.3 72.2 0.0 3.7 5.5 1.5 1.7 0.1 0.0 0.6 1.8 1.0 0.3 22.3 0.0 0.0 7.3 0.0 0.1 1.1 0.0 0.0 0.4 29.7 0.7 0.9 51.8 0.0 3.6 2.7 0.2 0.2 6.8 0.5 1.4 1.3 0.0 70.3 1.0 0.4 1.7 4.1 0.0 0.0 2.5 2.6 5.6 2.8 3.4 7.2 2.8 0.2 0.1 0.0 4.0 1.3 0.7 0.0 1.5 0.6 0.2 0.0 20.2 0.0 0.5 0.0 4.9 2.0 0.6 1.0 0.0 1.1 0.3 3.0 3.2 0.0 0.1 TSPAN9 NET-5 ENSG00000011105 "Tetraspanin 9" O75954 12 3077355-3286564 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 128.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 68.7;Extravillous trophoblasts: 105.1;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 96.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 213.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 58.1" HPA014002 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" Cytosol "HPA014002: AB_2304038" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-2)" "unprognostic (3.53e-2)" "unprognostic (3.11e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" "unprognostic (1.26e-2)" "unprognostic (1.89e-1)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" 25.4 12.9 11.0 7.1 12.1 0.6 25.0 96.6 13.5 29.6 9.7 18.0 7.9 32.3 11.5 15.4 23.2 35.2 128.8 6.9 12.6 45.8 54.8 35.8 5.4 12.3 13.0 35.3 13.1 28.1 8.6 58.7 14.5 27.6 6.2 14.8 18.0 24.4 16.8 27.9 12.3 23.6 8.6 20.6 13.4 5.1 17.1 19.1 18.4 12.4 7.1 18.4 22.3 7.6 1.5 12.7 20.1 16.1 19.2 15.5 48.3 26.7 82.3 20.1 26.1 30.6 11.6 0.8 23.9 14.6 19.7 3.1 9.5 9.6 11.8 5.0 9.3 36.3 8.5 20.6 42.2 0.2 3.0 17.7 7.4 40.4 16.9 50.4 55.7 1.1 1.0 1.1 17.6 16.7 0.0 0.8 25.5 7.8 7.4 9.9 213.0 3.1 61.7 7.4 36.8 22.6 18.8 36.6 16.4 45.9 13.7 0.2 27.2 8.5 28.8 14.8 25.7 0.2 0.6 0.3 20.3 0.5 10.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.2 11.0 12.1 96.6 13.5 6.9 12.6 12.3 13.0 14.5 8.6 17.1 7.6 60.1 0.0 4.1 10.4 0.8 19.2 13.3 22.4 13.1 68.7 19.8 9.0 50.1 11.5 6.5 12.9 2.1 53.1 0.2 1.7 5.9 21.1 3.0 2.3 24.9 43.1 6.0 5.3 16.8 9.1 105.1 22.2 2.0 5.7 0.0 13.0 41.0 36.7 6.2 33.7 45.5 2.3 2.0 3.2 3.5 4.1 17.4 7.1 12.4 30.9 0.8 4.0 0.0 9.0 2.0 9.9 0.6 17.3 1.4 13.8 2.4 22.4 2.5 4.7 19.7 1.4 20.9 1.3 3.4 9.7 11.9 80.7 1.5 6.4 2.5 10.5 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 TYW1B "LINC00069, MGC87315, NCRNA00069, RSAFD2" ENSG00000277149 "TRNA-yW synthesizing protein 1 homolog B" Q6NUM6 7 72558744-72828200 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 21.9;Excitatory neurons: 47.4;Inhibitory neurons: 27.7;Oligodendrocyte precursor cells: 23.1;Oligodendrocytes: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA013568, HPA014118, HPA043136, HPA047029, HPA047052, HPA052097" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 37: B-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA013568: AB_2668852, HPA014118: AB_2668941, HPA043136: AB_2678333, HPA047029: AB_2679909, HPA047052: AB_2679918, HPA052097: AB_2681723" "unprognostic (2.61e-1)" "unprognostic (3.54e-1)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (1.91e-2)" "unprognostic (6.22e-3)" "unprognostic (3.88e-2)" "unprognostic (1.64e-2)" "unprognostic (1.19e-2)" "unprognostic (8.96e-3)" "unprognostic (5.78e-2)" "unprognostic (2.90e-2)" "unprognostic (4.33e-4)" "unprognostic (1.02e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (5.90e-2)" 2.3 1.8 2.4 1.3 2.3 2.9 2.5 2.0 2.6 4.1 6.9 1.8 1.0 2.4 2.9 2.0 2.3 0.9 1.5 2.5 2.3 1.8 4.5 1.6 1.7 1.8 1.4 5.3 2.0 1.7 2.1 1.8 1.9 2.6 2.4 2.5 1.8 2.7 3.4 2.6 1.7 1.3 1.5 1.9 2.0 2.9 1.8 2.4 3.4 1.1 2.5 2.6 3.1 3.1 2.4 2.5 1.0 2.0 1.5 0.5 1.1 1.2 0.5 1.0 1.1 8.0 4.1 7.4 0.7 0.8 1.0 1.1 1.9 0.8 1.2 8.0 2.3 0.7 1.2 4.7 0.8 7.6 2.0 3.6 0.5 1.2 0.8 0.6 0.7 1.6 10.3 7.5 1.0 1.0 2.5 3.8 1.8 3.1 4.5 1.4 5.4 2.7 1.1 0.8 1.7 0.9 1.5 8.2 4.5 3.1 2.1 2.6 3.1 1.8 4.1 9.4 1.4 6.5 8.4 8.2 0.5 2.1 9.5 3.0 1.9 3.3 1.5 0.8 1.3 4.7 0.9 0.9 0.7 2.3 1.1 1.4 2.2 1.2 0.8 2.9 1.0 0.6 2.4 2.3 2.0 2.6 2.5 2.3 1.8 1.4 1.9 1.5 1.8 3.1 3.5 0.0 2.0 21.9 7.2 0.0 1.8 0.0 2.2 4.3 3.4 3.4 5.3 2.8 0.6 0.0 10.4 4.8 5.4 2.1 0.0 2.9 4.9 3.6 7.6 3.2 0.0 3.2 47.4 0.7 1.7 3.3 4.6 5.3 1.3 2.0 1.8 2.7 3.1 1.7 27.7 2.9 0.0 1.0 0.0 1.1 0.9 3.0 0.0 15.0 3.2 0.9 2.1 23.1 41.4 0.8 2.3 0.7 5.8 2.2 2.0 0.7 1.5 8.0 0.0 6.9 5.2 5.6 5.2 5.4 0.0 1.9 5.1 5.4 2.2 1.1 VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144867 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 20.6;Excitatory neurons: 15.2;Muller glia cells: 38.9;Oligodendrocyte precursor cells: 49.8;Rod photoreceptor cells: 45.1" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 12.3" "Lineage enriched" "Detected in single" 17 "dendritic cells: 12.3" "Cell line enhanced" "Detected in some" "HeLa: 6.6;HMC-1: 9.0;MOLT-4: 12.9;U-266/70: 40.5" "Region enhanced" "Detected in many" "olfactory bulb: 27.1" "Low region specificity" "Detected in many" HPA062707 Approved Approved "Focal adhesion sites" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Focal adhesion sites" "HPA062707: AB_2684842" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (8.58e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" 12.5 0.8 2.2 0.9 1.6 0.4 2.5 0.6 6.9 16.8 1.4 13.8 1.7 6.8 12.2 1.4 4.5 2.5 16.4 2.1 2.0 1.1 0.4 0.6 1.1 2.2 0.8 12.0 17.5 0.9 2.7 5.7 2.6 9.2 1.1 6.5 0.3 20.5 7.4 0.7 4.8 4.2 2.1 0.8 8.6 2.2 1.3 8.2 0.2 5.4 0.4 6.8 11.2 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.2 12.9 0.1 1.0 0.0 0.0 3.2 0.1 0.7 0.0 0.0 2.8 2.3 0.1 0.2 0.0 0.3 0.0 0.7 0.0 0.0 0.4 0.0 0.0 40.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 12.3 0.0 0.1 2.2 1.6 0.6 6.9 2.1 2.0 2.2 0.8 2.6 2.1 1.3 2.9 0.8 0.0 0.0 2.9 0.7 0.6 2.9 0.0 1.8 1.7 1.6 1.8 7.5 0.0 0.0 0.0 2.1 0.0 20.6 0.0 0.0 0.0 1.3 0.4 6.9 0.4 0.0 0.0 15.2 6.7 0.0 10.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.3 1.9 10.2 0.5 1.8 1.9 0.0 38.9 4.1 49.8 0.3 0.8 0.0 2.6 2.4 2.0 0.0 0.5 0.0 45.1 0.0 2.9 5.6 3.6 10.2 0.1 0.0 0.0 3.8 0.1 0.0 0.3 WARS2 mtTrpRS ENSG00000116874 "Tryptophanyl tRNA synthetase 2, mitochondrial" Q9UGM6 1 119031216-119140654 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028007, HPA069692" Enhanced Supported Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028007: , HPA069692: AB_2686172" "unprognostic (1.00e-1)" "unprognostic (2.25e-1)" "unprognostic (2.03e-1)" "unprognostic (5.64e-2)" "unprognostic (3.42e-1)" "unprognostic (7.05e-2)" "unprognostic (7.73e-3)" "unprognostic (3.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.17e-2)" "unprognostic (3.96e-2)" "unprognostic (6.76e-3)" "prognostic favorable (1.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.83e-1)" "unprognostic (9.88e-3)" "unprognostic (4.71e-2)" 7.3 8.8 2.4 4.1 2.4 1.9 9.4 2.4 3.0 6.9 6.5 7.3 7.7 6.3 3.8 6.1 9.4 4.9 7.9 2.3 2.6 9.6 6.1 5.0 4.7 2.4 2.4 8.2 8.9 10.2 3.8 6.3 2.4 5.7 8.0 6.0 5.4 3.5 6.3 5.2 5.1 5.2 2.4 3.0 7.2 4.6 2.3 4.6 6.8 6.5 5.1 6.8 5.6 2.8 12.8 5.0 7.5 7.9 9.6 21.6 7.6 7.0 10.5 7.6 9.1 14.4 5.6 19.0 11.4 12.0 4.2 8.2 13.9 12.6 11.7 9.8 16.6 8.9 12.8 13.9 19.6 14.8 4.8 16.1 9.7 11.1 20.2 10.0 11.7 7.9 14.1 13.4 14.4 15.7 8.9 8.6 9.9 9.8 10.6 6.3 24.9 9.9 20.9 17.5 10.7 6.6 11.3 15.4 16.7 13.1 6.9 11.1 8.8 7.8 9.2 15.2 13.8 6.4 4.6 8.3 9.6 12.1 14.7 0.0 5.0 0.3 3.4 3.6 5.0 4.6 3.6 4.5 6.7 6.2 4.2 4.2 0.2 4.2 2.2 3.2 4.5 3.4 2.4 2.4 2.4 3.0 2.3 2.6 2.4 2.4 2.4 2.4 2.3 2.8 7.2 9.6 12.3 22.5 10.4 9.6 17.6 14.7 14.2 6.7 13.1 11.3 10.6 5.7 11.2 11.0 6.2 16.9 7.0 6.5 17.6 9.8 57.7 15.2 8.6 7.5 6.7 18.9 15.5 11.9 15.3 15.5 17.9 13.8 8.8 9.7 2.2 7.5 9.5 6.7 21.4 10.2 14.2 10.0 6.9 31.8 9.9 8.2 10.6 11.2 13.0 5.0 3.1 12.1 18.2 8.7 6.1 8.2 9.1 13.1 7.5 18.8 14.7 8.2 6.6 12.0 10.1 5.4 6.1 19.8 10.7 20.0 10.2 19.6 15.8 14.4 WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573670-9593457 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 213.9;Glandular and luminal cells: 262.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004619, HPA068845" Approved Approved Nucleoli No No "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoli "CAB004619: AB_628447, HPA068845: AB_2686048" "unprognostic (6.04e-2)" "unprognostic (1.90e-3)" "unprognostic (1.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-2)" "unprognostic (3.79e-3)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-2)" "unprognostic (3.21e-3)" "unprognostic (3.73e-1)" "prognostic unfavorable (5.19e-4)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" 12.7 5.6 1.5 14.1 1.3 23.0 46.1 2.4 2.3 21.5 2.8 18.4 10.6 62.6 24.5 46.3 18.6 49.0 43.0 1.2 2.3 16.8 57.8 11.6 24.8 2.8 4.0 10.9 10.1 17.8 8.4 34.6 3.6 21.2 14.4 4.5 17.4 12.7 10.4 57.1 13.5 35.0 2.2 8.1 17.2 31.5 2.0 23.7 26.6 7.2 30.2 53.0 15.4 1.9 43.1 16.4 69.1 38.8 65.2 29.8 125.9 48.8 44.8 29.3 29.8 33.8 53.3 100.7 18.0 27.6 30.8 48.8 49.0 23.3 41.1 33.3 30.7 43.1 30.1 26.2 7.0 66.6 39.7 12.0 25.3 13.8 53.8 34.9 21.6 43.6 64.0 75.8 55.7 13.2 63.5 39.4 97.6 36.9 18.5 57.6 54.5 24.6 28.1 100.0 25.0 31.8 39.9 48.6 29.2 89.3 27.1 32.9 21.7 51.1 35.2 23.0 42.2 14.4 51.1 140.1 23.3 36.5 41.0 0.0 0.0 6.0 1.7 0.0 0.2 8.0 1.7 3.0 0.1 4.7 0.1 1.3 0.1 1.9 0.0 0.1 7.1 0.6 1.5 1.3 2.4 2.3 1.2 2.3 2.8 4.0 3.6 2.2 2.0 1.9 17.2 51.3 33.9 0.0 36.8 176.4 170.4 38.5 213.9 1.8 168.5 67.2 61.1 65.8 53.5 42.3 0.0 94.8 11.2 54.7 13.7 24.9 25.0 160.1 86.2 18.7 61.1 40.4 0.1 13.6 200.1 39.2 52.5 262.4 7.0 28.5 9.7 85.0 17.0 1.7 0.4 65.6 18.3 2.5 21.9 41.7 11.8 10.0 17.8 1.0 2.4 9.9 8.2 2.0 0.1 24.8 38.5 10.9 17.2 82.7 35.9 8.3 62.6 7.1 6.6 180.7 23.7 61.4 44.4 181.4 191.1 137.2 19.0 11.8 55.5 85.5 WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 80.2;Peritubular cells: 197.5" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.4;HSkMC: 8.0;SuSa: 3.4;TIME: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA047274: AB_2732539, HPA066368: AB_2685664" "unprognostic (2.08e-3)" "unprognostic (2.06e-3)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (9.42e-2)" "unprognostic (4.90e-3)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (5.65e-4)" "unprognostic (5.41e-2)" "unprognostic (7.64e-2)" "unprognostic (4.80e-2)" "unprognostic (2.49e-2)" 4.5 1.9 2.0 1.5 4.9 0.1 2.8 2.1 2.8 8.2 2.0 5.6 3.0 4.9 2.8 5.8 4.7 2.8 4.3 1.9 1.7 2.4 1.0 6.3 0.8 1.8 1.7 10.9 1.8 0.6 2.3 4.8 1.9 6.1 5.3 5.5 2.2 13.9 1.6 11.1 5.2 2.2 1.4 1.7 3.8 3.8 1.8 0.2 1.9 0.8 0.7 5.6 9.1 2.3 0.4 0.3 2.2 0.5 2.2 4.4 0.4 1.0 1.0 0.2 0.4 0.2 0.5 1.1 0.2 1.1 0.2 1.4 0.7 0.3 0.2 0.0 0.4 0.1 0.8 0.3 1.8 0.2 0.5 8.0 0.8 0.4 0.1 1.3 1.2 0.3 0.1 0.2 0.2 0.3 0.1 0.1 0.3 0.0 0.3 0.1 0.3 0.0 1.5 0.3 0.3 0.3 0.7 0.1 0.7 3.4 0.0 0.2 3.5 0.3 1.4 0.8 0.3 0.1 0.1 0.0 0.9 0.1 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.0 4.9 2.1 2.8 1.9 1.7 1.8 1.7 1.9 1.4 1.8 2.3 7.6 12.8 3.3 2.0 2.0 10.1 1.8 6.1 5.2 14.1 2.1 0.9 6.5 1.5 3.9 1.8 27.1 2.1 2.4 3.5 0.0 0.8 5.6 2.6 3.6 10.2 8.4 2.1 5.5 1.4 0.8 17.7 1.1 6.8 2.5 2.8 6.1 0.2 1.1 5.0 6.2 2.2 4.1 2.1 8.2 3.4 80.2 4.0 3.6 30.9 2.2 9.8 0.0 11.6 7.1 2.0 4.8 197.5 2.5 4.4 2.9 0.9 4.6 27.6 0.0 9.7 2.7 5.9 5.5 26.4 13.9 1.9 1.9 2.0 1.5 2.6 XPR1 "SLC53A1, SYG1, X3" ENSG00000143324 "Xenotropic and polytropic retrovirus receptor 1" Q9UBH6 1 180632022-180890279 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 100.9;Excitatory neurons: 118.2;Inhibitory neurons: 102.5;Microglial cells: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SH-SY5Y: 145.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016557 Supported NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA016557: AB_2669382" "unprognostic (2.65e-1)" "unprognostic (2.68e-2)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.86e-1)" "unprognostic (1.30e-3)" "prognostic unfavorable (3.04e-4)" "unprognostic (2.76e-1)" "unprognostic (2.59e-1)" "unprognostic (3.78e-2)" "unprognostic (4.72e-2)" "unprognostic (6.44e-2)" "unprognostic (8.82e-2)" "unprognostic (7.04e-2)" "unprognostic (1.38e-1)" "unprognostic (2.59e-1)" "unprognostic (8.44e-2)" 7.7 9.0 6.4 7.3 7.8 6.2 6.6 4.5 8.0 19.3 13.8 9.2 11.0 10.9 7.4 7.2 15.3 8.5 30.3 5.3 10.5 20.3 6.3 10.1 5.9 5.6 8.7 7.3 12.6 20.3 6.1 14.1 7.6 6.5 9.9 10.1 6.1 10.1 5.4 4.2 11.0 9.8 5.5 7.0 4.6 16.7 11.5 8.5 13.6 8.3 6.7 12.4 4.4 4.7 16.1 22.6 54.4 19.1 17.9 24.1 51.5 18.2 24.1 12.1 12.9 32.6 23.2 15.2 42.3 21.1 19.2 42.7 22.0 32.3 17.8 21.4 14.1 19.7 15.0 23.3 20.9 16.6 20.7 20.2 31.3 17.2 35.5 19.7 26.7 20.2 61.3 24.7 28.8 14.7 15.9 7.6 51.4 20.3 4.9 16.6 19.5 20.2 30.8 32.8 34.6 145.7 25.0 22.0 16.0 37.0 19.5 18.8 22.3 15.9 15.3 22.9 23.1 27.3 27.5 29.9 11.5 16.3 26.4 0.9 4.5 2.1 3.1 8.4 2.7 1.6 2.8 2.8 3.8 2.0 2.6 2.7 4.3 2.8 13.4 1.1 3.2 3.2 6.4 7.8 4.5 8.0 5.3 10.5 5.6 8.7 7.6 5.5 11.5 4.7 22.4 9.6 14.4 100.9 11.2 25.6 19.7 22.6 55.8 16.3 11.0 9.1 47.3 15.7 15.0 5.5 27.1 13.7 5.3 20.2 3.9 22.3 19.4 27.1 13.3 21.3 12.0 18.3 118.2 44.6 6.6 10.7 8.2 48.2 7.6 11.6 15.0 11.9 9.8 13.5 102.5 7.0 20.3 21.4 17.7 9.7 4.7 14.8 10.6 102.1 9.7 8.1 12.3 79.9 47.5 23.5 12.4 14.3 13.4 13.5 25.6 24.3 23.0 10.5 6.6 8.9 10.5 15.5 17.5 22.3 17.0 7.7 13.4 10.0 10.4 14.1