Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCA3 "ABC-C, ABC3, EST111653, LBM180" ENSG00000167972 "ATP binding cassette subfamily A member 3" Q99758 16 2275881-2340746 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 91.2" "Cell type enriched" "Detected in many" 6 "Alveolar cells type 2: 427.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 34.6;SCLC-21H: 45.9;T-47d: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007884 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cytosol" "HPA007884: AB_1078077" "unprognostic (2.64e-1)" "unprognostic (2.19e-2)" "unprognostic (6.09e-3)" "unprognostic (2.61e-3)" "unprognostic (2.20e-1)" "unprognostic (1.35e-1)" "unprognostic (2.90e-2)" "unprognostic (1.86e-1)" "unprognostic (6.58e-3)" "unprognostic (3.67e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-2)" "unprognostic (5.33e-2)" "unprognostic (3.32e-2)" "unprognostic (7.85e-2)" "unprognostic (2.91e-1)" "unprognostic (1.30e-1)" 6.8 8.7 19.1 3.0 20.8 0.7 6.7 10.2 25.5 3.0 0.0 7.9 2.0 3.7 3.5 2.9 4.4 2.7 6.1 23.4 17.1 6.5 1.1 91.2 3.7 20.1 15.8 3.4 13.1 11.2 11.1 4.3 22.2 4.9 1.2 7.4 9.1 4.3 6.2 4.3 3.9 4.6 11.1 3.4 4.9 8.9 19.1 11.3 24.6 3.8 6.5 4.5 2.2 19.7 0.7 21.6 4.1 33.1 0.8 0.0 0.3 5.8 1.4 2.3 2.4 3.0 3.4 0.2 8.4 2.7 2.1 0.6 19.2 0.3 0.8 34.6 12.9 2.2 2.5 0.5 2.9 0.4 3.6 0.3 0.5 0.3 1.1 13.4 32.4 0.2 24.0 0.0 0.1 29.3 0.1 2.4 4.4 5.2 10.4 5.4 0.7 3.8 18.7 0.7 45.9 33.0 4.1 23.4 0.6 1.6 76.5 2.0 9.3 0.2 1.1 9.0 9.8 6.1 2.9 0.1 4.7 11.7 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.4 0.1 0.0 0.0 0.1 19.1 20.8 10.2 25.5 23.4 17.1 20.1 15.8 22.2 11.1 19.1 19.7 4.3 70.5 427.4 30.0 1.1 0.6 0.5 0.2 2.2 20.7 8.4 6.7 6.7 4.3 9.5 18.4 12.5 0.0 2.1 0.3 0.0 5.7 7.7 1.3 0.3 6.3 5.4 0.0 60.3 3.8 0.0 2.7 0.0 2.9 29.7 7.7 5.3 0.7 1.0 18.5 58.6 0.8 4.1 1.2 1.8 3.8 1.8 3.1 1.8 13.1 2.2 7.1 2.1 32.2 37.2 1.9 0.4 3.4 3.6 1.5 0.4 2.0 2.4 12.5 6.6 7.2 2.9 5.1 15.0 1.2 1.6 0.0 3.9 1.3 0.4 0.2 ABCD2 "ALDL1, ALDR, ALDRP" ENSG00000173208 "ATP binding cassette subfamily D member 2" Q9UBJ2 12 39550033-39619803 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.7;brain: 8.9" "Cell type enhanced" "Detected in some" "Astrocytes: 71.5;Bipolar cells: 57.2;Excitatory neurons: 33.2;Inhibitory neurons: 34.2" "Cancer enriched" "Detected in single" 7 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in single" 4 "T-cells: 4.2" "Group enriched" "Detected in some" 6 "ASC diff: 11.6;HDLM-2: 16.9;Karpas-707: 29.0;SH-SY5Y: 17.3;U-266/70: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.26e-3)" "unprognostic (4.06e-4)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (2.06e-1)" "unprognostic (7.31e-5)" "unprognostic (3.42e-2)" "unprognostic (2.90e-2)" "unprognostic (8.06e-3)" "unprognostic (3.43e-2)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-4)" "unprognostic (5.04e-2)" "unprognostic (8.04e-2)" "unprognostic (1.13e-1)" "unprognostic (6.74e-2)" 15.7 1.7 1.5 1.7 2.2 0.2 2.8 8.9 5.2 5.3 0.0 0.7 0.5 2.7 0.2 0.4 2.7 0.5 4.2 2.1 2.1 0.5 0.1 0.5 2.8 2.2 3.3 0.1 0.1 0.0 0.5 0.0 2.4 0.4 0.7 5.9 2.6 0.6 0.1 0.1 0.7 2.6 1.3 1.6 0.7 0.2 3.6 1.4 0.2 0.3 1.6 0.9 0.6 1.4 0.0 0.0 0.1 0.0 11.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 16.9 0.0 0.1 0.0 0.0 0.6 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 9.8 1.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 1.2 0.5 2.8 3.7 0.1 0.3 3.2 4.2 0.1 0.9 0.0 0.6 3.6 1.2 1.5 2.2 8.9 5.2 2.1 2.1 2.2 3.3 2.4 1.3 3.6 1.4 0.4 0.0 0.0 71.5 2.6 0.0 0.0 0.0 0.0 57.2 0.3 0.3 10.9 0.0 0.0 0.0 6.2 0.0 3.8 0.1 0.0 0.0 0.3 0.2 0.5 0.2 0.0 0.0 33.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.1 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.5 1.1 2.2 0.0 13.0 1.3 0.0 0.0 0.7 5.9 0.0 0.0 0.9 2.4 2.3 0.0 0.4 2.5 0.2 0.1 0.0 0.0 0.0 7.8 0.6 0.1 0.0 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 166.8;Langerhans cells: 188.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "hTERT-HME1: 73.5;TIME: 70.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" 9.3 3.2 5.9 4.9 6.7 2.7 5.7 6.1 6.1 5.4 2.0 4.6 2.8 3.7 2.7 2.5 3.2 11.8 3.9 7.4 5.0 3.6 2.7 6.5 2.7 3.8 4.4 3.5 5.7 4.2 3.8 4.1 3.9 3.5 3.3 9.2 3.5 2.6 3.1 4.2 3.2 4.5 3.0 2.7 3.7 4.4 5.6 4.1 3.8 4.2 2.5 6.4 4.0 4.8 24.2 13.1 8.7 5.8 7.3 16.8 5.3 26.3 21.6 31.9 23.1 9.9 7.2 13.7 18.9 19.2 21.7 11.0 12.6 9.1 44.6 8.5 11.4 6.7 12.4 4.9 13.3 7.5 2.1 15.6 11.6 45.3 73.5 13.9 36.2 7.0 16.1 3.8 42.6 6.5 5.9 4.0 8.3 5.0 4.3 8.6 14.4 6.5 10.8 4.0 5.2 11.9 22.0 7.0 53.8 13.2 6.2 6.4 70.7 33.3 24.5 15.7 42.8 7.0 9.3 14.1 15.6 4.0 32.4 1.4 0.3 0.0 0.5 0.1 0.2 0.5 0.3 0.3 0.2 0.7 0.4 0.5 0.6 0.5 0.1 0.5 0.2 0.1 5.9 6.7 6.1 6.1 7.4 5.0 3.8 4.4 3.9 3.0 5.6 4.8 33.5 22.4 24.0 44.1 14.4 46.9 43.6 16.3 12.5 40.0 18.7 9.5 8.9 22.8 10.8 11.0 166.8 9.3 7.7 15.5 11.7 14.3 15.6 12.3 23.4 67.2 27.0 9.9 81.6 13.9 8.2 67.6 10.2 21.5 17.1 19.5 31.1 15.3 22.9 25.2 62.0 11.0 10.2 34.9 188.1 32.2 15.2 67.7 69.4 45.0 13.9 11.3 8.2 72.4 57.1 45.5 16.0 13.5 10.3 42.6 9.9 9.4 11.0 35.7 6.6 32.3 30.5 17.8 30.5 11.5 38.4 10.4 12.4 11.6 14.9 25.3 ACAN "AGC1, CSPG1, CSPGCP, MSK16" ENSG00000157766 Aggrecan P16112 15 88803436-88875353 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.5;seminal vesicle: 3.1" "Group enriched" "Detected in some" 15 "Extravillous trophoblasts: 127.1;Granulosa cells: 132.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "WM-115: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016377, HPA038241, HPA038242" Enhanced "Secreted to extracellular matrix" NA NA 17000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB016377: AB_626650, HPA038241: AB_2675909, HPA038242: AB_2675910" "unprognostic (2.69e-3)" "unprognostic (4.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.43e-2)" "unprognostic (2.13e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-1)" "unprognostic (7.12e-2)" "unprognostic (8.57e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (7.79e-2)" "unprognostic (1.53e-1)" "unprognostic (7.71e-2)" "unprognostic (7.27e-2)" 1.2 0.2 0.6 0.9 1.0 0.1 0.1 2.2 1.6 0.9 0.1 0.3 0.1 0.4 0.2 0.1 0.2 0.7 0.5 0.7 6.5 0.7 0.1 0.7 0.1 2.1 1.6 0.4 0.2 0.1 0.4 0.2 1.5 0.5 0.3 0.1 0.1 3.1 0.2 0.2 0.1 0.5 1.3 0.2 0.2 1.4 1.5 0.0 0.3 0.0 0.0 0.8 0.7 1.4 0.0 0.0 0.0 0.0 0.8 0.0 4.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.2 1.6 0.7 6.5 2.1 1.6 1.5 1.3 1.5 1.4 0.1 0.0 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.0 1.2 0.0 127.1 0.7 0.0 0.4 1.3 132.4 0.0 0.0 2.5 0.0 4.5 0.0 0.0 0.0 0.5 2.1 0.0 0.2 1.8 1.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 8.4 2.3 6.3 0.0 0.4 3.6 0.1 1.8 0.0 0.4 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 31.3;brain: 10.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.2;Leydig cells: 31.7;Oligodendrocytes: 55.8;Proximal enterocytes: 17.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 10.9;HDLM-2: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 29.7" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 31.3 2.5 3.2 0.6 6.3 0.1 6.2 1.3 3.5 0.5 0.0 4.1 4.1 0.1 0.3 0.2 0.1 0.3 0.4 6.4 10.2 0.4 2.2 0.2 0.5 1.4 1.9 3.6 1.5 0.0 2.2 0.1 1.3 0.2 3.0 0.4 0.8 0.3 0.8 0.3 3.4 0.2 0.9 0.1 2.1 0.4 6.6 0.2 0.2 0.3 0.3 0.1 0.2 3.8 1.5 0.0 0.0 0.1 10.9 0.3 0.2 0.3 0.3 0.1 0.3 1.7 0.2 0.0 0.1 0.9 0.7 0.0 0.1 0.0 0.2 5.1 0.7 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.1 0.6 1.9 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.2 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.2 6.3 1.3 3.5 6.4 10.2 1.4 1.9 1.3 0.9 6.6 3.8 0.5 0.0 1.1 14.7 1.4 0.6 0.7 0.9 1.8 0.8 0.9 0.3 1.9 0.0 0.9 0.0 0.0 0.2 0.3 14.3 0.0 0.2 1.9 0.4 4.9 0.7 7.8 0.0 26.2 0.2 0.8 0.9 2.6 0.5 0.0 0.4 1.1 5.9 0.1 0.0 11.0 9.2 2.0 0.0 1.3 2.9 31.7 0.1 3.6 3.7 4.3 1.8 0.0 3.5 55.8 0.4 7.6 9.1 2.9 1.8 17.7 1.1 0.2 0.3 0.0 0.6 0.8 0.4 2.4 0.7 1.4 0.3 2.5 0.4 13.5 0.5 ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9556732 "CD markers, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 154.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010738, HPA051575" Approved Supported Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol "HPA010738: AB_1078100, HPA051575: AB_2681539" "unprognostic (2.28e-1)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.12e-3)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (3.69e-1)" "unprognostic (3.53e-3)" "unprognostic (3.13e-1)" "unprognostic (3.82e-3)" "unprognostic (8.63e-2)" "unprognostic (2.61e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (4.23e-5)" 10.3 5.5 8.7 9.1 8.6 5.8 10.4 7.8 10.6 8.7 9.5 5.4 4.1 7.2 11.4 10.0 6.5 9.0 6.7 8.6 9.4 4.7 4.6 14.6 8.5 9.7 8.3 8.9 4.1 7.9 4.2 20.1 9.4 4.0 6.8 4.5 6.2 6.3 6.9 11.1 6.1 8.6 8.3 9.3 5.1 9.9 9.1 9.6 6.6 6.8 12.7 10.4 7.1 10.4 10.0 18.2 23.2 25.9 45.9 34.7 45.4 8.6 25.4 16.1 24.6 19.2 31.6 33.4 18.1 18.8 42.1 21.9 16.4 29.4 22.6 8.4 12.1 15.8 14.7 13.9 68.0 20.7 17.8 41.2 32.2 25.1 47.5 26.6 46.0 8.7 30.0 12.3 17.3 8.7 8.5 23.4 19.2 13.7 4.6 14.3 21.6 20.5 25.8 18.7 11.7 28.6 14.9 16.5 30.1 27.0 6.6 19.4 29.0 25.5 12.0 19.1 22.1 15.1 17.5 29.6 20.2 11.1 31.1 5.0 3.7 2.8 1.0 3.7 1.9 1.7 0.9 1.1 2.3 0.9 0.9 1.0 5.5 1.2 2.5 0.7 1.1 0.9 8.7 8.6 7.8 10.6 8.6 9.4 9.7 8.3 9.4 8.3 9.1 10.4 53.8 48.1 66.9 19.6 34.5 130.0 48.2 37.0 19.9 25.2 40.8 26.4 3.6 27.1 38.8 31.3 54.2 29.8 37.7 20.7 5.9 23.7 72.1 30.0 32.0 45.1 19.7 16.8 66.7 19.4 45.1 44.1 13.7 51.5 30.9 31.3 41.4 13.5 34.6 10.1 46.2 13.8 12.2 80.4 84.5 16.0 19.0 76.9 40.9 42.2 40.3 12.9 16.5 26.7 41.5 20.9 18.3 16.1 23.2 57.2 12.9 7.0 37.2 41.4 39.5 79.4 27.3 35.7 35.2 33.7 154.7 56.0 30.1 17.7 15.4 104.3 ADAMTS14 ENSG00000138316 "ADAM metallopeptidase with thrombospondin type 1 motif 14" Q8WXS8 10 70672506-70762441 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.9;gallbladder: 6.7;placenta: 7.6" "Group enriched" "Detected in some" 5 "Oligodendrocytes: 44.8;Paneth cells: 14.6;Theca cells: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.1;K-562: 10.4;RH-30: 5.4;U-138 MG: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (5.98e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-3)" "unprognostic (2.40e-1)" "unprognostic (5.33e-3)" "unprognostic (2.35e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.98e-2)" "unprognostic (6.81e-2)" "unprognostic (3.84e-13)" "unprognostic (3.90e-2)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" "unprognostic (2.16e-2)" 0.8 0.2 2.6 3.2 5.9 0.6 0.3 2.0 5.4 1.0 0.4 2.7 2.3 0.7 0.4 1.0 0.5 6.7 0.7 2.9 3.7 0.5 0.3 1.7 1.1 3.2 4.3 0.2 0.2 0.0 0.1 7.6 3.2 0.6 1.8 0.0 0.8 0.1 0.1 1.3 3.2 2.2 1.4 0.4 1.4 0.5 10.9 0.4 0.2 0.3 0.7 2.5 0.4 9.9 0.0 0.0 0.1 0.3 0.2 4.0 0.0 1.0 3.2 0.3 1.7 0.0 9.1 0.0 0.7 1.7 0.4 0.7 0.0 0.0 0.1 3.6 0.0 0.3 0.0 0.2 0.0 0.0 2.4 0.3 0.1 0.8 0.2 1.0 0.0 0.0 10.4 0.0 1.3 0.0 0.0 0.9 0.3 0.1 0.0 0.0 5.4 0.2 0.0 0.0 3.4 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 8.9 0.1 0.7 0.5 0.8 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.9 2.0 5.4 2.9 3.7 3.2 4.3 3.2 1.4 10.9 9.9 0.1 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.1 0.5 0.1 0.3 0.0 2.1 0.3 0.0 0.1 2.1 0.0 0.2 4.5 0.1 0.0 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.0 44.8 0.1 14.6 0.0 0.1 0.0 0.7 0.0 1.4 0.0 0.0 1.8 1.1 0.0 0.0 0.2 0.1 0.4 0.0 17.9 0.5 0.1 ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;placenta: 20.6" "Cell type enhanced" "Detected in some" "Adipocytes: 36.8;Granulosa cells: 15.0;Muller glia cells: 13.7;Oligodendrocytes: 16.9;Rod photoreceptor cells: 7.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 11.6;HUVEC TERT2: 8.0;SuSa: 10.6;TIME: 2.5;U-87 MG: 4.8" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Yes NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" 3.1 0.1 1.3 0.3 3.0 0.0 2.9 11.0 2.5 1.2 0.5 0.0 0.1 0.8 0.0 0.1 0.2 0.6 0.0 1.8 2.7 0.2 0.0 0.1 0.1 4.3 2.4 0.1 0.3 0.0 0.8 20.6 3.7 0.4 0.0 2.0 1.3 0.1 0.6 0.1 0.0 0.6 1.7 0.0 0.0 0.2 2.4 0.9 0.0 0.0 0.0 0.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.6 0.0 0.5 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.0 11.0 2.5 1.8 2.7 4.3 2.4 3.7 1.7 2.4 5.9 36.8 0.0 0.0 4.6 0.1 0.1 0.1 0.0 0.0 1.8 1.5 4.3 0.6 0.0 0.0 1.8 2.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.3 0.0 15.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.1 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.0 0.0 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 ADARB1 "ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1" ENSG00000197381 "Adenosine deaminase RNA specific B1" P78563 21 45073853-45226560 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing" "Hydrolase, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.9;Excitatory neurons: 54.1;Horizontal cells: 69.0;Inhibitory neurons: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 65.8;HHSteC: 65.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029645 Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA029645: AB_10602106" "unprognostic (2.69e-1)" "unprognostic (7.65e-2)" "prognostic unfavorable (8.16e-5)" "unprognostic (1.82e-2)" "unprognostic (1.07e-2)" "unprognostic (9.07e-2)" "unprognostic (3.29e-2)" "unprognostic (6.97e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (1.28e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.57e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-2)" "unprognostic (2.38e-2)" 15.4 7.0 14.9 10.3 13.2 5.2 11.4 39.1 26.5 14.7 29.6 35.7 3.0 23.0 6.3 7.4 13.6 8.1 10.1 20.0 17.9 9.5 7.0 35.2 13.4 30.6 17.2 7.8 6.1 9.3 6.1 12.3 30.8 17.9 4.8 28.6 6.8 8.1 13.6 15.9 10.8 11.7 8.7 16.1 19.0 4.5 22.7 5.7 6.6 11.8 8.7 60.4 11.9 12.7 7.0 1.0 5.3 6.2 6.3 4.3 7.2 4.6 7.6 14.4 9.0 10.9 1.1 2.2 12.1 22.6 7.9 0.6 7.8 19.1 15.9 1.7 7.0 15.2 65.8 7.2 65.7 10.5 7.2 23.7 8.1 5.1 14.9 5.4 15.4 20.4 3.5 0.8 42.2 5.1 6.8 10.0 8.6 3.4 10.1 2.0 5.0 7.1 3.2 2.3 30.6 8.2 36.4 1.6 11.6 8.5 3.5 8.2 16.3 4.7 5.7 19.4 17.5 6.6 3.1 1.8 4.3 24.1 25.8 0.7 0.0 2.4 0.4 0.2 0.8 1.0 1.1 0.7 0.0 2.6 0.7 0.6 0.1 0.3 0.2 1.0 0.8 0.2 14.9 13.2 39.1 26.5 20.0 17.9 30.6 17.2 30.8 8.7 22.7 12.7 29.0 0.0 1.1 10.7 12.0 11.1 2.9 3.4 2.8 62.9 6.2 7.1 21.6 1.5 1.9 0.0 12.5 0.5 5.9 0.9 0.0 1.3 2.7 1.6 8.8 21.2 0.0 2.1 54.1 0.5 1.2 9.4 2.6 1.6 8.2 5.5 14.3 6.3 5.9 69.0 85.7 0.9 0.0 3.4 4.9 2.9 3.7 3.2 5.4 37.5 5.0 34.2 2.1 16.1 4.8 1.0 0.1 5.7 4.0 5.5 0.3 2.7 0.7 16.0 0.0 32.9 12.7 11.4 17.7 1.5 7.2 1.0 13.7 1.4 1.2 2.3 ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24920237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 58.4;Sertoli cells: 111.7;Smooth muscle cells: 62.8;Theca cells: 92.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010223 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010223: AB_630839" "unprognostic (3.05e-1)" "unprognostic (1.10e-1)" "unprognostic (4.91e-2)" "unprognostic (1.39e-3)" "unprognostic (5.01e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-1)" "unprognostic (6.06e-2)" "unprognostic (8.43e-2)" "unprognostic (6.89e-2)" "unprognostic (8.22e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.32e-9)" "unprognostic (3.74e-2)" "unprognostic (5.56e-2)" "unprognostic (1.11e-1)" "unprognostic (8.55e-3)" 94.4 17.3 43.5 17.3 55.1 17.7 74.6 36.7 50.1 66.7 28.4 27.5 10.9 56.4 20.5 30.4 62.1 23.0 36.6 43.3 43.4 25.9 6.6 42.5 18.9 41.6 43.8 71.9 15.7 17.0 41.7 83.6 41.1 40.6 15.8 4.2 21.6 33.0 15.2 38.4 34.4 35.3 36.9 30.4 25.0 9.8 50.6 11.4 36.8 20.4 18.1 36.4 48.9 44.9 76.5 40.4 17.2 28.3 84.5 75.4 29.6 32.3 65.9 37.1 37.8 38.6 25.1 26.0 6.2 53.2 51.0 54.5 43.1 54.5 24.0 58.4 55.8 43.0 40.0 1.7 64.0 24.0 24.6 55.7 47.5 36.6 50.8 23.6 33.8 27.9 15.5 49.2 19.3 43.6 17.9 2.1 14.9 39.9 24.4 38.8 75.3 59.5 15.5 38.7 31.6 19.1 45.8 54.2 30.2 13.0 13.5 22.5 33.5 59.7 34.2 39.1 54.1 42.4 101.6 113.6 18.7 39.2 31.4 2.6 1.5 0.0 0.4 1.6 0.3 5.5 0.9 0.5 9.5 6.0 0.7 0.5 0.0 1.2 0.4 9.0 3.4 1.0 43.5 55.1 36.7 50.1 43.3 43.4 41.6 43.8 41.1 36.9 50.6 44.9 14.6 0.0 1.8 17.0 8.2 11.0 4.2 4.1 5.2 3.0 18.6 8.0 2.8 0.0 1.3 1.8 0.0 1.0 5.2 5.0 0.0 0.9 0.3 1.9 42.2 10.6 1.2 5.2 40.1 0.0 2.1 25.5 2.0 2.2 18.4 3.7 5.0 0.3 12.6 0.0 36.8 6.0 2.0 5.4 6.9 3.9 58.4 10.1 7.2 21.5 4.0 1.6 0.0 15.1 33.2 1.0 5.8 29.3 4.9 11.2 8.3 0.2 1.1 2.2 111.7 6.5 62.8 0.4 2.4 4.4 11.8 1.2 7.2 92.9 12.1 3.9 ADIRF "AFRO, APM2, C10orf116" ENSG00000148671 "Adipogenesis regulatory factor" Q15847 10 86968432-86983934 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1238.9" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 12067.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.5;naive CD8 T-cell: 1.9" "Lineage enriched" "Detected in single" 8 "T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 847.5;PC-3: 680.7;RT4: 1035.2" "Low region specificity" "Detected in all" HPA026810 Approved Supported Nucleoplasm,Cytosol NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cytosol" "HPA026810: AB_2672003" 1238.9 58.8 253.4 50.9 238.3 1.0 246.1 221.8 380.1 201.9 226.1 114.2 476.9 114.1 49.1 114.2 235.9 46.7 90.6 251.6 278.5 147.2 82.5 209.5 15.5 259.4 237.0 252.6 73.2 26.9 55.1 28.4 241.8 312.5 48.1 29.0 296.8 233.8 87.5 115.6 491.6 75.8 239.8 73.6 75.2 27.2 242.7 25.8 116.6 131.9 44.7 242.9 171.1 247.4 259.8 4.9 0.1 0.1 123.3 224.9 16.1 97.0 166.9 1.7 0.4 6.5 29.5 0.0 3.4 209.9 8.4 847.5 0.0 39.7 1.0 9.1 0.0 0.0 22.5 1.8 19.9 0.2 3.4 1.9 132.0 0.6 70.1 6.7 50.4 3.6 0.3 36.3 4.0 130.4 0.6 6.5 0.0 6.4 680.7 0.5 0.0 3.4 14.6 1035.2 11.8 3.0 36.0 222.0 1.7 0.0 270.7 2.7 132.6 3.4 17.4 13.2 0.6 4.0 3.3 0.4 6.3 0.0 5.1 0.0 0.2 0.0 0.0 0.0 0.6 0.0 1.0 0.0 0.3 0.0 2.5 1.9 0.0 0.0 0.0 0.0 0.5 0.3 253.4 238.3 221.8 380.1 251.6 278.5 259.4 237.0 241.8 239.8 242.7 247.4 1215.2 1842.9 476.5 3.9 15.0 528.4 141.9 309.7 39.9 5.4 651.4 253.2 0.0 58.6 614.4 187.6 2.1 299.2 14.3 658.7 1352.0 29.9 9.6 55.7 63.9 944.9 30.0 37.5 0.1 272.1 16.9 508.0 121.3 195.1 48.9 11.7 1691.7 257.4 26.4 0.0 0.3 418.7 128.1 17.3 492.0 48.4 1309.5 25.3 610.1 10.3 99.9 703.9 0.0 1.0 0.2 336.8 1115.3 469.8 3.4 481.9 12067.2 1144.8 88.2 16.5 1472.6 705.4 2422.0 3.2 6.2 35.0 438.6 166.8 40.7 2.4 443.5 1160.7 ADRA1D "ADRA1, ADRA1A, ADRA1R" ENSG00000171873 "Adrenoceptor alpha 1D" P25100 20 4220630-4249287 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.6;cervix: 7.2" "Cell type enhanced" "Detected in some" "Endothelial cells: 1.2;Excitatory neurons: 2.1;Inhibitory neurons: 2.4;Oligodendrocyte precursor cells: 1.0;Smooth muscle cells: 2.4" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.7;BJ: 7.5;CAPAN-2: 3.3;fHDF/TERT166: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038789 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA038789: AB_10673475" "unprognostic (5.37e-2)" "unprognostic (4.65e-1)" "unprognostic (8.73e-2)" "unprognostic (7.75e-11)" "unprognostic (7.83e-3)" "unprognostic (1.54e-2)" "unprognostic (7.62e-2)" "unprognostic (7.82e-4)" "unprognostic (4.41e-3)" "unprognostic (8.37e-2)" "unprognostic (6.09e-2)" "unprognostic (7.24e-3)" "unprognostic (7.71e-7)" "unprognostic (5.21e-3)" "unprognostic (2.76e-1)" "unprognostic (6.01e-3)" "unprognostic (3.32e-5)" 1.2 0.4 5.0 0.0 0.6 0.0 0.8 0.3 4.8 7.2 0.0 2.0 0.0 3.5 0.3 0.2 2.0 0.2 0.3 7.5 4.2 0.3 0.1 2.3 0.0 2.7 4.9 0.6 0.3 0.2 0.0 0.1 2.4 3.4 0.1 0.0 0.2 1.7 0.5 0.4 0.2 0.3 1.3 1.4 1.6 0.7 9.6 0.0 0.8 0.4 0.0 2.4 2.9 1.1 0.0 1.7 0.1 0.0 0.0 0.0 0.0 7.5 1.3 0.4 0.1 0.3 3.3 0.0 0.0 4.4 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.6 0.3 4.8 7.5 4.2 2.7 4.9 2.4 1.3 9.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 ADRB1 ADRB1R ENSG00000043591 "Adrenoceptor beta 1" P08588 10 114043866-114046904 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.7;lung: 13.1;placenta: 29.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 85.7;Cytotrophoblasts: 84.5;Sertoli cells: 52.6;Syncytiotrophoblasts: 38.4" "Cancer enriched" "Detected in many" 10 "prostate cancer: 12.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.1;PC-3: 2.6;THP-1: 4.5;TIME: 5.8;U-937: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067972 Enhanced NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA067972: AB_2685936" "unprognostic (1.45e-3)" "unprognostic (1.18e-3)" "unprognostic (1.44e-1)" "unprognostic (4.92e-2)" "unprognostic (3.22e-1)" "unprognostic (8.88e-2)" "unprognostic (9.28e-2)" "unprognostic (3.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-2)" "unprognostic (2.77e-4)" "unprognostic (1.33e-1)" "unprognostic (7.80e-3)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" 4.0 0.2 5.5 0.3 10.3 0.5 2.3 0.7 12.0 0.1 0.2 3.1 0.9 0.1 0.1 0.9 0.1 0.1 23.7 6.8 3.3 1.1 1.4 13.1 0.2 1.8 3.1 0.0 1.3 0.8 0.8 29.1 2.4 4.4 0.6 2.1 5.4 0.1 2.3 0.4 1.9 0.1 0.9 1.5 0.7 0.5 5.0 0.1 0.6 0.0 0.3 0.7 0.1 7.8 1.4 0.8 0.1 0.8 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.3 1.0 0.2 0.2 0.0 0.4 0.3 0.1 0.1 0.1 7.1 0.4 0.3 0.1 0.1 0.0 0.2 0.4 0.0 0.7 0.0 1.3 0.1 0.1 1.0 0.0 0.1 0.1 0.8 1.1 0.9 0.3 0.2 2.6 0.2 0.2 0.1 0.0 1.1 0.1 0.2 0.0 0.5 0.0 0.3 0.2 4.5 5.8 0.2 0.1 0.1 0.1 0.0 0.0 0.3 0.0 3.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 10.3 0.7 12.0 6.8 3.3 1.8 3.1 2.4 0.9 5.0 7.8 1.1 19.2 7.8 15.0 0.5 1.0 3.9 0.8 1.2 21.8 1.0 0.5 85.7 2.8 9.8 0.0 0.0 84.5 3.0 0.1 1.9 0.1 0.1 0.4 0.6 11.3 0.0 0.0 12.8 0.2 5.2 5.3 0.0 0.3 0.0 0.0 0.4 0.2 4.4 13.5 2.5 3.3 2.0 2.2 1.6 0.2 0.0 2.8 1.8 7.5 0.6 0.7 3.1 1.0 0.3 0.1 1.4 0.4 1.2 6.1 0.8 0.0 12.1 1.7 52.6 0.4 8.2 0.5 0.2 0.1 0.0 38.4 4.8 0.0 0.6 3.9 ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;ovary: 11.7" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.8;Hofbauer cells: 1.1;Langerhans cells: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "medulla oblongata: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Fibroblasts - ECM organization" "HPA061969: AB_2732674" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" 0.3 0.0 1.2 0.4 1.1 0.2 0.3 0.5 0.9 0.4 1.5 2.1 0.2 0.7 1.1 0.1 4.1 1.7 0.0 0.9 0.7 0.0 0.0 0.1 0.1 8.1 2.7 11.7 0.0 0.0 0.0 2.9 3.1 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.0 4.6 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.5 0.9 0.9 0.7 8.1 2.7 3.1 0.4 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 AMOTL2 LCCP ENSG00000114019 "Angiomotin like 2" Q9Y2J4 3 134355347-134375479 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 89.2;Suprabasal keratinocytes: 130.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 259.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063027 Approved "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA063027: AB_2684924" "unprognostic (2.23e-1)" "unprognostic (2.55e-2)" "unprognostic (7.01e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (6.09e-2)" "unprognostic (1.57e-2)" "unprognostic (9.84e-2)" "unprognostic (4.40e-2)" "unprognostic (2.32e-1)" "unprognostic (3.02e-1)" "unprognostic (2.85e-2)" "unprognostic (1.49e-1)" "unprognostic (8.09e-2)" "unprognostic (3.59e-1)" "unprognostic (7.67e-2)" "unprognostic (3.85e-1)" "unprognostic (1.17e-2)" 80.0 11.1 24.1 7.1 42.5 0.2 55.9 26.0 32.7 34.4 32.0 28.3 7.7 44.3 9.1 37.1 37.5 22.8 25.9 17.5 22.9 25.6 17.2 33.4 11.9 40.8 35.0 21.5 27.2 9.6 5.7 33.6 33.6 24.6 5.5 5.4 25.1 15.8 16.8 39.7 15.8 16.7 21.6 20.5 23.1 4.2 36.3 4.3 29.5 15.9 7.2 29.1 33.3 70.2 99.1 43.1 29.6 30.9 30.3 37.3 259.9 97.5 54.8 87.6 43.0 132.5 30.3 0.0 119.9 69.4 50.0 72.2 19.4 26.3 39.9 0.2 2.2 0.2 22.7 14.4 56.8 0.2 0.2 53.7 79.5 34.5 39.7 35.1 42.3 0.9 0.7 0.2 59.2 31.7 0.3 0.3 37.9 21.4 16.3 0.2 37.4 0.3 56.4 22.7 4.5 11.7 73.8 94.3 68.8 66.8 88.2 0.8 72.4 59.5 53.2 41.7 59.7 0.1 0.3 0.4 22.1 0.1 68.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 42.5 26.0 32.7 17.5 22.9 40.8 35.0 33.6 21.6 36.3 70.2 24.0 60.9 17.3 2.6 0.2 72.9 18.4 15.4 30.1 10.4 29.2 21.5 15.6 52.9 16.4 18.4 18.8 30.4 1.1 6.5 17.6 27.5 4.0 59.7 29.1 30.1 12.5 0.0 4.5 13.1 29.9 30.3 20.4 89.2 1.3 34.1 51.8 25.8 3.0 1.7 5.8 3.6 6.1 1.6 7.8 10.9 35.8 1.7 14.2 9.4 0.0 12.1 0.0 18.6 56.9 52.8 4.2 19.9 0.0 30.0 10.6 19.3 16.2 5.1 13.1 12.1 46.1 0.2 0.6 25.3 130.1 24.8 2.6 8.7 4.5 37.3 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANKRD65 ENSG00000235098 "Ankyrin repeat domain 65" E5RJM6 1 1418420-1421769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 65.0;Glandular and luminal cells: 88.4;Respiratory ciliated cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "myeloid DC: 3.5;plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 23 "dendritic cells: 7.8" "Group enriched" "Detected in some" 8 "Hep G2: 35.9;RT4: 34.5;SCLC-21H: 46.3" "Not detected" "Not detected" HPA065720 Enhanced Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA065720: AB_2685545" "unprognostic (2.17e-2)" "unprognostic (2.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.77e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.64e-1)" "unprognostic (4.39e-1)" "unprognostic (1.16e-1)" "unprognostic (4.43e-2)" "unprognostic (5.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.81e-2)" "unprognostic (8.04e-2)" "unprognostic (2.76e-2)" 6.0 1.0 24.6 3.2 29.5 0.2 10.3 25.6 25.9 8.8 18.5 14.2 2.3 7.6 5.9 15.6 36.7 2.9 4.1 22.0 25.2 6.0 1.5 11.2 9.1 31.0 28.5 8.5 15.2 1.4 2.3 6.9 29.4 19.9 1.7 2.5 16.1 21.9 3.1 7.0 6.3 4.0 24.0 1.6 9.9 7.3 25.7 7.8 4.3 3.3 7.2 21.1 9.4 34.8 1.0 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.5 0.9 0.0 4.5 0.3 4.3 0.0 0.5 0.4 0.0 0.0 35.9 0.8 0.1 0.0 0.4 5.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 0.1 0.0 0.3 4.6 0.0 0.0 34.5 46.3 0.5 0.2 0.0 0.1 0.4 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.3 0.0 0.3 0.0 0.0 0.0 7.8 0.0 0.2 24.6 29.5 25.6 25.9 22.0 25.2 31.0 28.5 29.4 24.0 25.7 34.8 11.8 22.4 29.0 5.5 0.1 2.2 12.9 14.1 13.1 8.5 5.9 32.5 0.7 14.3 20.1 1.8 0.0 26.0 0.0 0.0 9.8 19.0 0.0 65.0 20.5 11.7 1.8 2.7 4.4 30.7 0.8 13.3 3.1 88.4 8.8 2.9 1.4 0.8 2.2 8.4 2.0 0.0 14.2 1.0 3.3 0.9 20.8 1.5 3.6 1.0 1.2 16.6 0.0 3.5 20.5 11.0 0.1 29.0 0.1 6.3 0.0 0.5 51.8 3.1 0.0 25.7 3.6 0.3 0.3 10.7 3.1 16.8 1.1 0.7 0.0 10.8 ANKS1A "ANKS1, KIAA0229" ENSG00000064999 "Ankyrin repeat and sterile alpha motif domain containing 1A" Q92625 6 34889255-35091406 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.0;Inhibitory neurons: 160.5;Microglial cells: 168.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SCLC-21H: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036768, HPA036769" Approved Approved Nucleoplasm,Cytosol NA NA 17000 "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA036768: AB_10670923, HPA036769: AB_10672473" "unprognostic (3.75e-2)" "unprognostic (2.67e-1)" "unprognostic (2.59e-2)" "unprognostic (7.79e-3)" "unprognostic (5.73e-2)" "prognostic favorable (7.48e-4)" "unprognostic (1.18e-3)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (2.18e-1)" "unprognostic (1.42e-1)" "unprognostic (1.38e-2)" "prognostic favorable (8.05e-5)" "unprognostic (1.76e-1)" "unprognostic (9.71e-2)" "unprognostic (2.23e-2)" "unprognostic (7.80e-2)" 15.0 19.1 15.2 8.0 13.9 5.7 15.0 16.4 15.8 10.9 13.8 29.0 10.5 10.7 7.4 15.4 20.1 10.0 18.6 12.7 13.4 13.1 10.7 18.8 9.3 15.6 17.0 17.4 9.4 16.4 8.4 27.8 17.4 11.7 9.0 22.9 9.2 15.4 20.1 15.6 14.3 14.3 14.0 23.0 14.8 16.5 22.1 7.6 13.8 9.5 5.7 27.2 13.1 11.9 15.4 7.3 14.8 14.2 6.5 6.4 22.3 6.0 6.7 7.2 8.7 18.4 9.7 10.4 10.0 6.4 13.1 15.7 17.4 17.6 8.3 8.0 21.9 7.3 9.2 13.7 4.0 11.8 6.7 7.4 14.9 9.3 12.3 7.7 15.9 10.7 12.6 4.4 6.4 10.0 7.4 12.8 10.7 20.3 8.4 8.9 8.3 10.6 14.5 27.9 58.5 14.8 10.3 14.1 43.7 18.1 11.1 13.0 13.9 7.3 9.2 7.6 8.9 6.7 10.9 5.5 5.6 16.8 20.3 0.0 0.6 0.5 0.2 0.9 0.4 0.4 0.2 0.4 0.5 0.1 0.3 0.2 1.1 0.2 1.5 1.1 0.3 0.4 15.2 13.9 16.4 15.8 12.7 13.4 15.6 17.0 17.4 14.0 22.1 11.9 48.2 80.1 11.4 54.2 4.4 12.1 9.1 4.2 4.0 28.8 11.3 14.4 25.3 11.5 8.3 12.9 64.6 8.9 5.5 17.2 0.0 7.3 12.7 32.1 7.4 31.7 13.2 5.7 94.0 5.9 7.5 10.0 13.3 35.6 2.5 17.2 47.5 6.6 11.9 8.4 160.5 11.0 18.3 29.2 10.9 11.3 12.8 18.9 5.4 168.6 8.1 21.7 10.3 90.5 75.9 10.2 7.6 30.1 6.4 13.3 10.0 7.0 29.0 45.4 19.7 10.3 13.5 6.9 5.9 8.5 20.5 12.4 4.8 5.9 9.2 14.9 ANO4 "FLJ34221, FLJ34272, FLJ35277, TMEM16D" ENSG00000151572 "Anoctamin 4" Q32M45 12 100717526-101128641 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 12.0;brain: 11.3;cervix: 7.6;ovary: 7.7;seminal vesicle: 8.1" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 536.3;Oligodendrocyte precursor cells: 276.9;Oligodendrocytes: 814.1" "Cancer enhanced" "Detected in some" "renal cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 20.0;LHCN-M2: 9.5;SK-MEL-30: 15.5;TIME: 31.8;WM-115: 11.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053412 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA053412: AB_2682140" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "unprognostic (4.58e-2)" "unprognostic (1.04e-1)" "unprognostic (1.20e-2)" "unprognostic (2.02e-1)" "unprognostic (3.76e-2)" "unprognostic (1.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.97e-1)" "unprognostic (4.72e-1)" "unprognostic (6.54e-2)" "prognostic favorable (5.48e-5)" "unprognostic (1.16e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.41e-1)" 0.2 12.0 5.1 0.0 10.4 0.0 0.1 2.3 6.8 7.6 0.0 0.1 0.3 4.4 0.3 0.0 0.2 0.0 0.1 5.3 5.8 0.1 0.0 0.0 0.0 6.6 7.1 7.7 0.5 0.1 0.8 0.1 5.7 4.8 0.1 0.8 2.0 8.1 0.0 0.0 0.2 0.5 2.6 0.0 0.0 1.0 9.5 0.7 0.1 0.0 0.4 0.7 0.3 11.3 0.0 0.0 2.2 0.0 1.1 1.4 0.0 7.0 6.2 5.7 2.8 0.0 0.0 0.0 0.0 20.0 0.0 0.3 7.2 5.9 5.3 0.0 0.0 0.0 2.9 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 9.5 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 15.5 7.6 0.0 0.0 31.8 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 10.4 2.3 6.8 5.3 5.8 6.6 7.1 5.7 2.6 9.5 11.3 0.3 0.0 0.0 31.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.1 5.7 0.3 7.8 0.1 4.2 0.0 124.9 0.4 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 536.3 0.0 0.0 0.0 0.0 2.3 0.6 0.1 0.0 6.5 0.0 0.0 0.0 276.9 814.1 0.0 0.0 0.4 0.0 0.3 0.1 0.1 0.0 0.3 0.0 0.2 0.6 0.6 1.8 0.0 0.0 0.0 0.0 3.6 0.0 0.0 AP000311.1 ENSG00000249209 "Novel protein similar to ATP synthase delta (OSCP) subunit domain" 21 33584687-33931607 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 6 "T-cells: 12.8" "Cell line enhanced" "Detected in many" "U-2 OS: 5.7" HPA039558 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA039558: AB_2676570" "unprognostic (4.72e-1)" 0.4 0.3 0.7 0.6 0.9 0.1 0.2 0.6 1.2 0.1 0.4 0.4 0.3 0.3 0.4 0.5 0.3 0.3 0.9 1.0 0.6 0.3 0.4 0.4 1.1 0.9 0.8 0.3 0.0 0.2 0.0 0.9 0.9 0.4 0.5 0.1 0.7 0.0 0.8 0.3 0.4 0.0 0.5 0.2 0.5 0.9 0.7 0.4 0.3 1.0 0.1 0.1 0.0 1.0 2.6 0.2 0.6 0.2 0.3 0.0 1.0 0.3 0.5 0.3 0.2 3.7 1.4 0.3 2.2 0.1 0.5 1.5 1.2 1.5 0.0 1.7 3.3 1.2 0.7 0.4 0.5 1.1 0.7 0.4 0.0 0.5 0.5 0.1 0.1 2.4 1.8 3.2 0.6 0.7 1.7 0.5 3.3 5.0 2.9 2.2 0.5 1.3 0.1 1.2 2.5 0.1 2.8 1.3 0.4 2.8 1.7 1.6 0.3 0.3 5.7 0.9 0.2 1.5 1.7 0.8 1.8 0.9 0.0 1.7 1.4 1.2 5.8 1.0 7.8 2.0 8.2 8.6 1.6 2.2 7.2 7.2 0.8 1.0 1.1 1.7 12.8 3.9 0.7 0.9 0.6 1.2 1.0 0.6 0.9 0.8 0.9 0.5 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 APBB2 "FE65L, FE65L1, MGC35575" ENSG00000163697 "Amyloid beta precursor protein binding family B member 2" Q92870 4 40810027-41216714 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Group enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 586.1;Oligodendrocytes: 803.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "naive B-cell: 5.6" "Lineage enriched" "Detected in single" 14 "B-cells: 5.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 138.7;TIME: 192.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023542 Approved Approved Mitochondria No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA023542: AB_1844909" "unprognostic (4.43e-2)" "unprognostic (4.40e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (5.91e-3)" "unprognostic (8.13e-2)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (2.51e-1)" "unprognostic (1.21e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.19e-3)" "unprognostic (9.35e-3)" "unprognostic (3.92e-2)" "unprognostic (2.29e-2)" "unprognostic (2.61e-1)" 41.6 9.1 23.1 5.4 42.3 8.6 25.1 38.1 24.5 16.1 3.7 13.9 8.3 14.0 5.9 8.9 13.1 16.1 21.5 20.6 30.6 16.5 14.7 18.6 7.4 42.9 39.6 32.1 10.8 8.5 8.5 17.6 39.5 8.7 7.7 15.7 8.6 9.8 28.7 12.6 7.0 14.9 25.2 14.8 11.3 8.5 36.7 13.2 33.6 21.7 5.6 10.7 13.1 72.9 19.4 9.4 20.6 28.8 64.9 50.7 45.2 38.5 45.8 14.0 24.5 34.1 40.2 33.9 20.7 16.5 44.5 5.6 36.5 49.4 25.0 1.1 7.3 0.4 23.5 21.1 65.0 19.2 1.1 76.7 24.6 42.5 43.0 58.2 138.7 19.0 1.1 0.7 86.1 16.3 6.3 3.6 17.1 9.8 17.9 50.9 58.6 38.4 19.9 8.9 27.2 15.4 11.7 6.6 6.9 23.7 17.2 2.2 192.3 20.1 59.5 13.8 61.1 8.1 18.5 41.2 20.7 30.8 24.6 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 23.1 42.3 38.1 24.5 20.6 30.6 42.9 39.6 39.5 25.2 36.7 72.9 58.8 80.1 14.5 46.7 5.0 10.7 3.8 10.4 7.4 7.6 25.5 13.6 22.5 12.8 6.3 9.2 6.2 14.4 0.5 5.2 7.9 3.8 14.5 5.6 32.8 39.4 3.0 5.3 121.3 6.4 2.8 25.2 12.8 7.5 1.3 13.5 47.2 13.8 3.2 62.2 171.3 4.0 16.2 4.0 6.7 23.1 35.8 2.5 7.2 164.9 0.1 9.3 0.0 586.1 803.4 6.2 6.7 37.2 0.2 2.7 5.5 6.3 4.0 7.6 59.2 43.2 51.4 3.8 10.8 7.3 11.9 6.0 1.2 24.0 7.4 3.6 APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654956 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;placenta: 54.0" "Cell type enriched" "Detected in some" 7 "Endothelial cells: 68.2" "Group enriched" "Detected in all" 6 "glioma: 44.2;renal cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "HUVEC TERT2: 502.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.50e-1)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (9.32e-4)" "prognostic unfavorable (6.09e-4)" "unprognostic (4.71e-2)" "unprognostic (2.25e-1)" "unprognostic (3.30e-1)" "unprognostic (9.12e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (8.42e-2)" 4.7 9.2 19.9 2.2 21.2 0.0 3.0 19.0 24.0 0.6 6.8 1.0 0.8 0.7 0.3 0.6 1.2 0.4 12.6 15.4 23.8 7.5 1.4 13.4 0.1 30.1 25.9 2.4 0.3 1.0 5.4 54.0 25.4 1.1 0.3 0.3 0.6 0.5 3.7 1.5 0.8 1.9 29.7 0.7 1.2 1.1 33.6 0.3 0.9 1.1 0.2 3.4 0.4 35.8 0.2 0.6 58.5 0.5 1.9 3.6 0.0 0.2 0.0 1.1 1.8 0.0 0.0 0.0 6.2 0.2 2.5 0.0 1.4 14.1 1.0 0.0 0.1 0.0 0.6 0.1 0.2 3.3 1.4 7.7 0.1 7.2 0.0 0.0 502.1 1.7 0.1 1.9 2.6 0.0 0.2 0.7 1.5 0.0 26.8 0.3 0.5 0.9 0.0 0.0 2.0 6.2 0.2 0.1 0.0 0.1 0.1 0.9 86.2 2.1 0.2 36.5 2.1 0.8 0.0 0.0 34.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 21.2 19.0 24.0 15.4 23.8 30.1 25.9 25.4 29.7 33.6 35.8 3.0 0.0 1.3 8.1 0.0 0.1 0.1 0.6 0.0 0.0 0.2 9.4 6.8 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.1 0.1 68.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 0.2 1.3 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.8 1.9 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.4 0.6 0.0 0.2 0.0 0.1 1.2 0.2 2.9 0.0 0.0 APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4485.3;Leydig cells: 2077.4;Melanocytes: 1028.1;Peritubular cells: 994.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 6 "ASC diff: 3507.4;ASC TERT1: 1918.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" 2071.8 84.8 949.6 13.9 1157.3 0.9 5037.8 1174.9 1364.1 620.2 1370.1 144.7 56.0 496.7 155.7 160.0 750.6 213.3 1007.8 952.8 1010.4 49.7 7.1 183.5 24.6 1148.3 1040.5 131.2 212.4 61.9 192.2 350.5 1122.0 419.8 57.2 0.8 1272.3 183.8 1154.9 970.1 88.4 96.2 1027.5 8.2 402.6 75.7 1070.2 113.5 828.8 625.3 20.8 434.4 591.7 1347.6 0.0 2.2 0.5 0.7 3507.4 1918.1 6.1 31.3 7.6 0.1 0.2 222.4 0.4 0.4 0.9 1.8 0.0 0.9 0.4 10.5 0.3 0.3 2.4 0.3 0.2 0.1 12.5 0.3 0.5 91.4 21.0 0.2 17.0 0.3 4.3 0.2 0.2 0.9 5.3 1.3 0.1 0.7 0.5 38.9 0.5 0.1 0.0 0.6 0.0 2.8 0.7 0.5 0.0 34.8 31.8 1.3 67.2 0.1 0.4 0.5 1.4 0.4 0.1 0.2 0.3 9.2 1.0 0.4 420.3 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 949.6 1157.3 1174.9 1364.1 952.8 1010.4 1148.3 1040.5 1122.0 1027.5 1070.2 1347.6 543.2 0.0 11.0 2.9 7.5 145.0 16.0 25.4 46.7 0.0 121.6 138.7 26.9 1.5 81.8 5.5 0.0 5.4 15.9 1.4 0.0 0.4 9.7 16.3 393.7 114.1 46.3 0.0 3.3 0.0 4.2 4485.3 7.7 7.0 0.0 0.0 21.4 0.0 13.3 0.0 2.1 0.7 10.2 0.3 193.2 51.0 2077.4 31.8 1028.1 279.2 1.0 0.0 0.0 300.6 221.5 2.3 0.3 994.5 19.2 25.7 0.0 0.2 128.9 0.0 19.7 100.3 210.7 10.5 4.0 24.1 102.6 5.9 23.5 7.0 0.6 47.3 AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 727.9;Alveolar cells type 2: 231.8;Cholangiocytes: 358.9;Endothelial cells: 606.7;Hepatic stellate cells: 325.6;Proximal tubular cells: 319.7" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.7;HeLa: 12.5;SH-SY5Y: 14.7;U-2 OS: 14.9;WM-115: 76.4" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.5;spinal cord: 22.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" 385.9 30.5 86.5 29.3 149.4 50.7 250.3 106.2 79.1 148.9 277.7 97.7 51.0 160.8 41.7 143.5 165.8 162.3 206.8 141.0 124.4 522.9 12.9 413.9 45.5 512.3 181.1 28.1 257.6 48.2 15.2 36.9 199.5 83.8 32.6 0.7 114.0 84.4 199.0 112.6 90.8 142.4 357.3 12.6 80.4 7.8 138.8 39.0 113.2 388.6 34.2 138.5 143.2 432.4 0.1 0.5 0.3 0.6 0.3 1.3 0.7 2.4 0.5 0.0 0.0 0.2 0.8 0.1 34.7 1.9 0.1 0.4 0.0 0.0 0.0 0.3 0.3 0.5 12.5 0.0 0.3 0.3 0.1 4.9 0.1 0.3 0.0 0.1 5.1 0.1 2.3 0.1 0.0 0.0 0.0 0.9 0.7 1.0 0.0 0.0 8.9 0.3 0.9 0.0 0.3 14.7 1.9 1.2 0.0 4.6 0.3 0.1 0.0 0.0 14.9 1.1 0.5 0.8 0.6 0.6 0.0 0.1 76.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 149.4 106.2 79.1 141.0 124.4 512.3 181.1 199.5 357.3 138.8 432.4 727.9 179.5 231.8 75.7 3.6 91.5 1.2 0.3 5.2 0.7 11.5 29.0 78.0 358.9 3.9 31.3 8.4 3.4 3.7 3.7 29.4 53.3 2.3 2.5 1.2 606.7 7.3 86.9 3.5 2.5 4.8 67.6 0.0 0.9 1.3 0.5 325.6 2.0 3.7 0.0 1.0 28.6 0.0 5.1 107.7 2.1 1.2 6.0 88.9 0.0 1.6 0.4 0.0 0.5 0.2 2.4 14.5 3.4 3.7 1.2 90.6 319.7 6.2 0.4 13.1 23.1 42.3 0.3 1.5 2.6 78.7 7.3 8.1 4.7 67.8 1.0 ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.8;Astrocytes: 123.1;Endothelial cells: 46.9;Langerhans cells: 54.1;Microglial cells: 125.5;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 35.0;TIME: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA036380: AB_10673129" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (9.90e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.75e-3)" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-3)" "unprognostic (5.86e-2)" "unprognostic (1.30e-1)" "prognostic favorable (8.45e-4)" "unprognostic (3.57e-2)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (7.79e-3)" 17.0 2.1 8.3 7.6 9.3 0.8 9.0 10.1 8.3 6.0 1.1 5.4 3.0 6.2 3.1 5.9 5.1 8.6 13.0 8.3 8.9 4.9 3.6 19.5 5.6 11.6 10.4 6.1 2.9 4.0 2.1 11.2 9.4 3.0 5.4 1.5 2.8 3.4 4.2 6.4 4.7 11.8 9.0 7.1 3.2 1.3 10.8 6.9 12.7 9.2 6.8 8.1 3.8 9.9 0.4 2.5 6.2 12.2 3.5 2.9 1.9 7.5 8.6 5.8 4.2 0.1 0.5 0.1 8.7 19.5 10.0 0.2 5.9 1.9 6.7 11.0 0.8 1.7 0.8 0.0 5.8 0.4 7.0 7.8 0.2 15.1 1.7 4.5 35.0 1.2 0.0 3.0 13.1 0.2 0.1 0.3 2.1 0.0 7.6 0.0 2.9 0.0 1.7 0.0 0.0 22.7 3.8 0.0 15.6 3.3 0.7 0.6 38.5 16.0 6.4 2.0 5.9 5.1 5.6 6.2 10.9 5.6 16.4 0.0 2.6 0.0 0.4 2.8 0.8 1.6 0.3 0.5 6.0 0.6 0.3 0.2 0.0 1.1 1.1 5.2 0.8 1.2 8.3 9.3 10.1 8.3 8.3 8.9 11.6 10.4 9.4 9.0 10.8 9.9 47.8 19.2 24.6 123.1 7.3 5.2 0.7 3.1 1.8 0.6 0.5 1.7 16.0 1.5 3.1 0.0 0.0 1.2 9.8 0.2 0.0 2.1 0.4 0.4 2.1 46.9 0.0 7.4 3.4 2.0 10.3 7.3 0.0 0.4 9.5 8.4 30.7 0.6 10.1 0.0 18.4 3.9 0.0 14.5 54.1 0.7 2.8 16.7 10.6 125.5 13.8 3.9 4.1 159.8 0.9 1.9 0.3 2.6 4.9 1.1 0.0 2.1 1.4 0.4 0.0 2.5 11.3 0.3 0.7 1.3 5.1 1.0 3.7 3.3 0.4 0.7 ARHGEF6 "alpha-PIX, alphaPIX, αPix, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136780932 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 193.9;Granulosa cells: 128.2;Microglial cells: 77.8" "Cancer enhanced" "Detected in all" "glioma: 24.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 117.6;HL-60: 153.7;HMC-1: 532.0;JURKAT: 152.7;U-937: 158.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003578 Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA003578: AB_1078203" "unprognostic (9.64e-2)" "unprognostic (3.47e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-2)" "unprognostic (7.28e-2)" "unprognostic (2.06e-3)" "unprognostic (9.08e-2)" "unprognostic (7.87e-3)" "unprognostic (4.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-3)" "unprognostic (5.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-3)" 44.0 16.2 23.4 30.5 24.4 31.4 23.5 25.0 19.5 10.7 11.6 13.2 7.5 12.9 5.3 7.6 7.0 17.3 32.9 25.2 26.9 6.7 8.5 25.6 41.8 26.8 29.2 16.5 3.9 10.3 6.2 46.9 27.8 7.8 11.1 4.6 8.7 8.8 68.7 6.2 14.4 16.6 29.0 39.4 12.3 3.8 26.5 51.4 5.6 54.7 39.6 14.3 8.7 30.1 1.1 0.0 5.1 0.0 11.2 28.5 0.1 1.6 9.5 1.5 8.2 0.0 0.0 5.5 2.3 8.0 7.8 0.8 6.1 0.0 1.5 28.1 2.0 117.6 0.1 0.0 4.2 153.7 532.0 30.9 0.1 5.4 0.1 10.1 3.0 152.7 0.5 22.1 20.4 0.2 70.6 88.4 4.9 0.0 2.3 26.6 37.2 0.1 1.6 29.5 0.3 6.7 0.2 1.2 4.0 2.6 3.5 61.2 0.5 7.6 1.2 9.3 7.2 3.6 0.1 57.3 35.1 158.2 10.1 57.2 16.4 71.3 13.8 18.9 16.0 6.2 15.4 11.3 19.1 5.4 13.7 12.3 9.1 12.4 16.1 6.0 21.5 15.3 23.4 24.4 25.0 19.5 25.2 26.9 26.8 29.2 27.8 29.0 26.5 30.1 18.1 6.4 8.9 57.1 22.4 1.1 0.9 0.8 1.2 0.8 16.1 10.8 60.0 0.0 2.4 1.8 0.0 0.3 23.6 0.1 1.9 0.6 12.0 0.9 2.4 13.2 0.0 11.3 20.6 1.8 0.4 10.7 5.6 1.6 193.9 128.2 12.5 2.5 15.2 13.5 21.6 0.4 0.0 46.5 25.1 35.8 14.9 40.3 3.6 77.8 36.1 4.7 36.0 48.2 4.3 0.7 0.0 14.7 12.8 0.4 0.0 0.2 2.2 0.3 13.1 33.5 18.5 0.7 0.7 0.6 1.7 0.4 40.5 30.1 0.1 0.7 ARRB1 ARR1 ENSG00000137486 "Arrestin beta 1" P49407 11 75260122-75351705 "Predicted intracellular proteins, Transporters" "Protein transport, Transcription, Transcription regulation, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 136.8" "Group enriched" "Detected in many" 5 "dendritic cells: 42.5;granulocytes: 49.5;monocytes: 136.8" "Cell line enhanced" "Detected in many" "HEL: 168.9;RH-30: 114.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003763, HPA049318, HPA070249" Approved Supported Nucleoplasm NA NA 1500000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB003763: AB_562248, HPA049318: AB_2680711, HPA070249: AB_2732151" "unprognostic (3.40e-1)" "unprognostic (8.37e-2)" "unprognostic (1.63e-1)" "unprognostic (1.88e-1)" "unprognostic (2.35e-1)" "unprognostic (3.27e-3)" "unprognostic (1.33e-2)" "unprognostic (1.15e-2)" "unprognostic (1.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (9.35e-2)" "unprognostic (2.34e-2)" "unprognostic (2.29e-1)" "unprognostic (7.10e-2)" "unprognostic (3.90e-1)" "unprognostic (1.26e-1)" 30.7 7.1 49.7 21.9 49.4 15.7 24.1 28.3 49.5 10.0 0.0 26.4 21.9 10.2 6.1 19.0 15.9 12.9 17.6 54.3 43.6 14.2 10.1 53.0 15.3 41.1 55.6 16.2 24.5 3.8 4.1 25.1 49.4 16.3 22.5 5.3 12.7 9.7 11.4 16.8 27.2 21.8 23.2 40.1 33.9 4.3 49.9 9.9 8.8 10.9 10.3 16.5 11.0 36.7 5.1 23.6 24.2 12.0 20.2 17.6 48.8 5.0 17.2 6.2 4.3 34.5 23.9 2.0 58.9 4.5 4.7 1.1 9.5 0.1 2.4 0.2 5.5 168.9 3.3 20.6 5.5 5.1 63.9 8.9 1.2 10.3 0.0 7.4 70.4 6.1 83.5 0.2 12.2 14.1 3.1 58.4 17.8 76.9 7.1 18.8 114.4 6.8 26.8 20.4 12.5 13.5 8.7 61.7 15.0 49.3 44.8 27.6 61.0 4.7 5.9 19.3 0.6 0.1 0.1 0.1 3.5 78.0 5.8 33.7 65.7 45.9 11.6 106.5 4.3 0.4 5.5 6.6 42.5 0.2 5.0 6.6 49.5 14.8 136.8 0.9 5.7 41.1 49.7 49.4 28.3 49.5 54.3 43.6 41.1 55.6 49.4 23.2 49.9 36.7 24.2 28.9 14.8 52.2 1.9 1.9 2.0 1.9 2.8 3.1 9.0 14.7 4.6 8.6 5.8 3.7 6.2 41.7 10.7 38.5 1.9 5.0 2.6 0.8 4.3 19.4 5.4 10.3 35.6 8.4 4.1 9.1 17.3 0.9 23.5 2.3 25.7 2.1 39.6 0.0 48.9 11.1 8.2 55.2 17.9 21.4 15.8 31.2 3.6 55.3 42.1 0.2 29.9 8.0 23.9 9.2 19.1 16.6 1.0 3.6 29.9 0.2 4.7 1.1 13.1 4.5 7.7 0.2 0.8 1.0 3.0 33.7 5.9 9.4 20.0 2.8 ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.1;Fibroblasts: 10.8;Melanocytes: 21.4;Smooth muscle cells: 6.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 15.7;HaCaT: 31.4;Hep G2: 19.9;hTEC/SVTERT24-B: 30.9;U-87 MG: 39.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA038386, HPA038398" Uncertain Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA038386: AB_10669781, HPA038398: AB_2675995" "unprognostic (6.08e-2)" "unprognostic (1.70e-2)" "unprognostic (9.41e-3)" "unprognostic (4.77e-3)" "unprognostic (1.54e-3)" "unprognostic (2.83e-3)" "unprognostic (2.76e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.06e-1)" "unprognostic (5.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-7)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.19e-4)" 1.2 0.3 1.6 2.3 2.6 0.6 0.4 2.5 2.1 2.7 0.7 1.6 0.6 3.1 0.6 1.8 2.1 1.1 1.3 1.4 1.8 0.7 0.4 4.5 0.3 3.6 2.4 0.4 0.4 0.6 1.0 2.8 3.9 1.7 0.4 0.4 0.5 0.8 0.8 4.8 0.7 2.8 2.6 0.8 0.8 0.4 2.8 0.3 0.2 0.5 0.4 3.8 2.7 5.5 1.0 3.8 1.1 0.0 0.0 0.8 0.0 8.1 12.1 15.7 11.5 1.1 1.8 0.0 3.1 11.5 1.3 31.4 0.2 5.3 5.6 0.0 0.1 0.0 0.4 19.9 1.5 0.0 0.0 0.8 3.4 30.9 0.9 10.7 0.2 0.0 0.0 0.2 2.5 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.1 0.4 0.0 0.2 0.0 6.7 0.9 1.3 11.2 0.0 0.0 0.0 0.3 10.2 0.3 0.0 0.0 0.0 0.0 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.6 2.5 2.1 1.4 1.8 3.6 2.4 3.9 2.6 2.8 5.5 0.1 0.0 0.0 0.3 0.0 12.1 0.0 2.4 0.0 0.1 0.1 0.4 1.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 1.1 10.8 0.0 0.0 4.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.1 0.0 0.8 0.2 0.6 0.0 21.4 0.0 0.0 3.9 0.0 0.0 2.5 0.4 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.3 0.0 1.8 6.6 0.1 0.9 0.9 4.7 1.4 1.1 0.0 0.0 0.0 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677271-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enriched" "Detected in many" 6 "Microglial cells: 216.4" "Cancer enhanced" "Detected in all" "melanoma: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 23.0;fHDF/TERT166: 22.9;HMC-1: 19.4;SK-MEL-30: 21.9;U-2197: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 6.5 8.7 13.7 2.7 9.3 2.5 5.3 6.0 8.9 2.0 0.7 3.2 0.8 1.5 0.1 1.9 2.3 3.7 2.0 5.9 5.8 5.8 0.6 7.1 1.8 9.9 9.7 1.1 1.4 3.5 2.1 1.7 9.5 2.2 0.8 0.1 7.9 0.6 0.6 2.5 3.0 2.8 5.9 1.5 3.2 4.3 15.0 1.1 2.5 0.7 1.1 2.5 1.4 4.9 0.0 5.7 1.3 0.0 2.2 2.8 0.0 23.0 9.3 6.1 9.9 0.0 0.0 0.0 1.6 22.9 0.0 0.0 9.3 1.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.0 19.4 0.9 0.0 0.6 0.0 2.5 0.0 1.2 0.0 0.0 3.3 0.0 1.2 0.0 1.5 0.0 1.5 4.4 4.6 2.8 9.9 0.0 0.0 0.1 0.0 0.0 21.9 0.0 7.4 1.2 0.0 8.9 0.2 12.7 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.3 0.5 0.1 0.0 0.7 0.6 0.0 1.2 0.0 1.0 0.1 0.3 13.7 9.3 6.0 8.9 5.9 5.8 9.9 9.7 9.5 5.9 15.0 4.9 0.3 32.1 8.6 2.0 0.8 1.0 0.0 2.7 0.6 0.2 2.6 1.8 1.7 1.5 5.3 0.0 0.0 0.0 11.1 0.1 0.0 0.5 23.2 2.8 2.8 4.2 0.0 0.0 4.5 0.0 0.1 5.0 3.1 7.9 15.2 0.0 0.4 0.1 2.5 0.0 2.1 0.2 0.0 2.5 5.2 21.8 4.1 4.5 17.8 216.4 2.3 0.0 14.4 1.5 2.7 0.8 0.0 17.7 1.7 0.7 0.0 0.1 4.2 0.1 0.0 4.7 9.1 0.4 1.2 0.0 0.4 0.0 8.6 0.1 0.0 0.0 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 BCAR3 "AND-34, NSP2, SH2D3B" ENSG00000137936 "BCAR3 adaptor protein, NSP family member" O75815 1 93561741-93847150 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.5;Basal prostatic cells: 149.0;Extravillous trophoblasts: 75.0;Urothelial cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0;memory B-cell: 1.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 159.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014858 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Centrosome "HPA014858: AB_1845302" "unprognostic (9.16e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.60e-3)" "prognostic unfavorable (8.41e-4)" "prognostic unfavorable (5.42e-4)" "prognostic unfavorable (8.92e-7)" "unprognostic (2.44e-1)" "unprognostic (3.66e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.51e-2)" "prognostic favorable (3.08e-7)" "unprognostic (2.13e-1)" "unprognostic (1.14e-1)" "unprognostic (7.05e-2)" "unprognostic (1.87e-1)" 31.0 10.6 17.7 6.6 20.9 1.0 18.5 19.3 15.3 10.0 21.1 15.3 13.4 5.7 3.6 8.1 9.5 7.5 13.1 14.8 18.7 15.9 11.9 14.2 13.8 21.1 20.6 11.4 4.2 4.0 4.6 17.0 18.9 8.9 16.6 1.5 21.9 9.5 24.4 15.6 12.9 8.0 19.0 4.8 16.2 6.3 21.7 4.3 10.4 21.1 13.0 13.6 9.8 17.8 56.0 23.4 43.5 3.4 18.4 14.4 37.1 56.9 98.3 45.9 28.1 4.0 40.9 9.0 18.9 88.1 59.4 34.0 1.3 73.5 39.7 4.0 1.3 0.0 16.2 10.3 33.1 0.4 0.2 17.3 79.5 47.5 159.7 44.1 51.1 1.1 1.6 0.3 125.7 8.6 1.0 0.2 13.6 24.5 79.7 3.7 62.7 1.3 120.4 70.1 1.5 3.6 27.4 29.1 36.1 16.8 32.9 2.2 60.8 67.3 17.5 29.2 76.0 4.5 2.1 1.2 10.1 0.2 25.2 2.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 0.3 1.6 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.0 17.7 20.9 19.3 15.3 14.8 18.7 21.1 20.6 18.9 19.0 21.7 17.8 26.9 3.2 7.2 72.5 10.2 9.8 149.0 11.3 2.8 0.9 7.9 13.5 7.1 11.5 11.7 14.7 0.0 27.5 2.5 30.8 27.4 11.3 11.3 13.3 2.6 17.9 14.9 0.4 5.2 6.3 75.0 6.3 15.8 16.6 3.8 33.7 5.7 10.3 11.9 21.9 11.2 20.7 8.2 5.3 12.7 12.8 10.2 8.3 19.6 64.6 9.4 4.0 0.0 3.0 2.1 28.0 22.0 1.2 8.9 36.3 25.8 23.7 18.1 0.4 72.3 23.8 19.9 4.2 3.7 4.8 10.2 18.9 3.7 8.3 10.3 106.1 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757955-95158448 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1;cervix: 24.7;prostate: 22.4" "Cell type enriched" "Detected in many" 7 "Astrocytes: 480.6" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.0;MCF7: 11.1;SH-SY5Y: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favorable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 0.7 4.6 13.4 0.3 15.4 0.1 1.0 13.5 15.0 24.7 2.1 0.9 0.1 4.4 2.4 0.2 12.5 2.6 0.8 12.5 16.0 7.8 0.8 1.7 0.0 19.3 20.1 6.2 1.1 0.1 1.9 0.7 17.5 22.4 0.2 8.1 1.0 14.2 3.0 0.8 0.1 0.6 15.3 0.9 2.4 3.7 15.6 6.4 0.5 1.1 0.0 0.2 0.5 12.1 0.0 22.0 5.6 0.0 2.3 4.8 0.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.2 1.0 0.0 1.3 3.6 8.4 0.1 0.0 4.9 0.0 1.4 0.0 0.6 0.5 0.1 2.7 9.0 2.8 6.2 0.4 0.1 0.0 0.0 0.0 7.1 11.1 0.6 0.1 2.1 0.1 3.2 0.2 3.4 0.1 4.3 0.1 0.2 18.8 0.3 3.2 3.2 0.8 1.7 0.0 0.0 4.0 3.8 0.2 4.3 0.0 0.0 0.0 1.5 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 13.4 15.4 13.5 15.0 12.5 16.0 19.3 20.1 17.5 15.3 15.6 12.1 0.0 6.4 0.0 480.6 0.0 2.7 1.3 13.1 1.2 0.4 3.8 1.0 3.4 2.8 33.4 60.7 0.0 0.0 0.0 0.0 1.9 3.0 1.4 28.5 1.4 1.1 18.4 0.0 51.0 0.4 0.3 1.5 0.0 20.8 0.0 38.6 2.9 0.0 0.1 0.0 2.5 0.0 8.2 0.0 1.2 1.4 3.1 0.4 28.4 22.5 0.0 38.5 0.0 10.1 2.8 0.7 0.0 3.8 0.0 28.5 0.0 0.2 15.7 1.6 0.0 1.7 2.9 1.2 10.6 0.4 2.3 0.0 0.5 4.4 0.0 1.6 BOC CDON2 ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Basal squamous epithelial cells: 112.1;Fibroblasts: 55.4;Leydig cells: 84.8;Peritubular cells: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 79.2;ASC diff: 113.6;BJ hTERT+: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA No 7900000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" 41.6 5.8 15.8 10.4 15.5 0.2 29.8 13.1 12.1 26.0 33.2 49.1 4.9 46.6 10.1 24.9 63.2 19.3 14.3 17.1 15.2 9.7 1.0 6.6 3.6 53.2 30.1 35.2 16.1 2.7 20.8 2.2 23.2 33.8 4.6 3.2 23.8 21.3 6.3 34.9 18.3 32.6 32.3 4.6 19.0 5.0 26.3 5.7 24.6 9.0 3.1 32.5 25.8 23.4 0.0 7.6 27.6 79.2 113.6 6.0 0.9 12.8 41.9 3.2 2.7 0.0 0.0 0.1 7.8 21.8 1.7 0.0 5.6 2.7 1.1 0.0 3.4 0.0 2.3 0.0 0.6 0.3 0.2 19.7 1.8 1.7 0.2 25.7 0.0 0.0 0.1 0.0 0.6 2.1 0.2 1.4 7.0 0.0 6.9 0.2 12.3 0.0 0.7 0.1 8.2 11.7 0.1 0.5 0.3 8.1 3.4 0.4 0.0 4.5 7.3 0.1 4.2 0.0 0.0 0.0 9.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 15.5 13.1 12.1 17.1 15.2 53.2 30.1 23.2 32.3 26.3 23.4 9.6 0.0 0.5 71.8 0.0 21.2 3.1 3.6 112.1 0.6 3.7 17.3 1.1 1.5 0.7 5.5 0.0 4.8 0.2 0.0 0.0 0.1 1.4 12.6 10.5 5.6 1.8 0.0 8.8 0.0 4.3 55.4 0.5 11.7 0.0 5.7 3.3 0.1 0.8 0.0 2.5 0.0 0.0 0.3 5.5 3.3 84.8 1.0 10.6 6.5 0.0 12.2 0.0 24.1 0.7 0.3 0.0 47.8 0.6 3.3 0.0 0.0 0.3 0.5 0.0 18.0 13.5 1.5 3.2 11.5 11.1 1.9 0.8 1.1 0.0 0.9 C14orf132 C14orf88 ENSG00000227051 "Chromosome 14 open reading frame 132" Q9NPU4 14 96039362-96093971 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 74.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Bipolar cells: 57.8;Endometrial ciliated cells: 55.2;Horizontal cells: 63.9;Skeletal myocytes: 44.9" "Cancer enhanced" "Detected in many" "glioma: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 49.9;SCLC-21H: 52.5;SH-SY5Y: 52.0;U-87 MG: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.47e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" "unprognostic (4.42e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.51e-2)" "unprognostic (5.55e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-2)" "unprognostic (1.33e-5)" "prognostic unfavorable (4.95e-4)" 5.9 14.0 57.3 3.2 58.1 0.1 6.9 62.8 69.1 23.3 20.5 23.8 2.1 26.2 14.2 7.1 22.5 5.0 4.1 74.7 52.5 9.9 4.1 18.4 0.8 53.6 49.8 5.2 3.2 0.1 38.8 0.8 50.9 9.5 4.4 12.8 3.0 19.8 3.0 13.8 14.2 22.3 51.2 6.2 15.7 1.3 55.8 3.1 2.4 6.6 1.2 8.5 11.9 56.1 0.0 6.4 30.8 9.7 22.0 22.0 0.1 10.6 23.8 13.6 8.3 0.1 0.1 0.0 2.4 23.8 9.0 0.7 3.7 0.8 11.7 0.0 1.4 0.1 1.2 0.1 2.7 0.0 0.2 12.0 1.2 12.7 1.0 0.0 0.2 3.0 0.0 0.1 6.3 49.9 0.8 0.1 15.0 0.0 0.0 28.5 5.0 0.1 11.0 22.4 52.5 52.0 8.3 1.0 1.5 8.3 28.9 1.4 0.0 10.8 6.5 18.0 0.0 0.0 0.0 0.1 46.1 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.2 57.3 58.1 62.8 69.1 74.7 52.5 53.6 49.8 50.9 51.2 55.8 56.1 4.8 38.5 10.6 14.7 0.4 2.7 3.7 5.9 5.2 57.8 0.7 7.1 1.9 1.5 3.9 7.3 20.9 0.3 0.2 0.0 5.9 5.8 3.0 55.2 23.8 8.6 9.0 0.0 20.3 0.2 1.0 16.6 2.0 6.8 1.3 5.4 19.2 4.0 0.3 63.9 11.2 0.1 4.1 0.6 7.1 3.0 15.8 0.5 8.8 7.5 0.1 4.0 0.0 11.1 24.7 1.2 0.1 13.5 0.1 2.1 0.0 0.0 13.6 6.1 0.0 44.9 4.4 0.3 0.6 6.8 7.7 0.3 1.0 0.6 0.1 2.3 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C20orf27 FLJ20550 ENSG00000101220 "Chromosome 20 open reading frame 27" Q9GZN8 20 3753508-3767781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 178.7;Hofbauer cells: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 144.6;intermediate monocyte: 249.1;myeloid DC: 199.4;non-classical monocyte: 235.3" "Group enriched" "Detected in all" 5 "dendritic cells: 199.4;monocytes: 249.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047483 Approved Approved Nucleoplasm,Cytosol NA NA 140000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA047483: AB_2680064" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.21e-3)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (1.69e-5)" "unprognostic (8.36e-2)" "unprognostic (2.07e-1)" "unprognostic (4.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (1.80e-1)" "unprognostic (2.16e-1)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" 55.8 24.0 48.8 20.4 125.4 103.6 45.2 44.7 70.9 39.5 33.7 117.3 17.0 42.5 8.7 29.6 51.8 25.5 27.9 45.6 63.3 25.7 24.7 20.8 24.5 52.9 59.3 66.3 23.6 9.4 23.3 8.9 67.5 24.2 7.8 4.9 15.7 10.9 22.4 26.9 33.9 14.1 43.8 45.5 86.8 22.7 59.5 11.0 23.4 11.5 9.8 73.9 26.3 40.7 172.9 177.7 24.4 106.1 49.5 28.1 42.7 45.5 25.1 70.4 50.3 120.5 61.6 111.1 41.4 48.2 94.7 140.9 65.7 101.9 24.9 26.1 138.3 63.2 35.9 212.6 36.2 88.2 24.7 41.0 41.8 93.3 46.1 24.2 48.2 72.9 114.6 59.8 37.3 240.2 107.6 186.3 114.9 107.0 248.4 86.6 67.9 123.7 43.9 62.0 121.8 56.6 41.2 155.3 85.1 10.4 36.9 96.8 35.9 104.8 73.8 171.6 129.6 50.5 93.2 80.7 31.5 161.2 53.9 1.3 144.6 2.3 28.7 249.1 42.1 38.7 33.6 38.6 199.4 36.2 37.6 37.5 5.4 32.5 235.3 38.7 34.2 87.4 48.8 125.4 44.7 70.9 45.6 63.3 52.9 59.3 67.5 43.8 59.5 40.7 54.0 0.0 3.3 3.3 26.5 24.2 23.0 26.8 35.3 9.7 28.2 45.7 3.7 8.6 7.4 11.0 2.1 17.5 15.8 10.2 29.4 32.6 21.8 13.8 178.7 28.7 15.7 99.1 6.0 30.0 49.2 27.1 14.3 7.5 22.9 45.0 19.6 17.9 142.9 1.7 9.5 15.9 16.2 119.0 53.1 15.3 32.6 92.2 37.4 5.6 97.4 24.6 15.5 3.5 2.1 34.7 14.6 24.8 20.2 46.6 19.3 32.4 2.7 13.6 65.7 17.1 98.8 27.3 39.1 34.8 32.8 7.3 24.1 69.7 33.0 22.7 C3orf70 ENSG00000187068 "Chromosome 3 open reading frame 70" A6NLC5 3 185076838-185153060 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;smooth muscle: 14.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Bipolar cells: 76.8;Melanocytes: 39.2;Oligodendrocyte precursor cells: 143.2;Peritubular cells: 49.7" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 3.9;SCLC-21H: 16.4;SK-BR-3: 7.2;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041861 Uncertain Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA041861: AB_10804119" "unprognostic (1.45e-1)" "unprognostic (2.17e-3)" "unprognostic (3.92e-3)" "unprognostic (2.77e-1)" "unprognostic (2.31e-1)" "unprognostic (6.62e-4)" "unprognostic (5.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (5.98e-3)" "unprognostic (9.91e-2)" "prognostic unfavorable (6.40e-6)" "unprognostic (1.06e-1)" "unprognostic (8.48e-2)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" 2.2 0.8 10.8 2.4 8.5 0.1 1.3 7.2 8.8 3.1 0.0 11.1 2.6 9.8 2.6 5.1 5.2 2.2 2.0 9.9 9.1 0.5 0.3 0.9 0.4 15.9 11.5 2.3 0.2 2.1 0.8 1.3 10.1 5.1 4.1 3.9 3.0 8.4 0.5 1.5 3.6 14.8 13.6 2.1 2.8 4.0 12.0 0.3 1.1 0.6 0.6 4.9 2.0 14.0 0.0 0.1 1.9 0.0 0.0 0.0 0.1 2.6 0.1 0.4 0.0 1.2 0.0 0.0 0.0 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.6 2.2 0.1 0.5 0.0 0.3 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.8 2.0 0.1 0.0 3.9 0.0 0.0 0.4 16.4 0.1 0.8 7.2 0.4 0.0 0.4 1.8 0.6 0.0 1.9 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.9 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.0 10.8 8.5 7.2 8.8 9.9 9.1 15.9 11.5 10.1 13.6 12.0 14.0 5.1 0.0 0.0 45.7 1.0 4.1 0.3 0.0 0.6 76.8 1.0 0.5 1.6 0.0 0.0 0.0 0.0 10.8 0.0 9.1 0.0 0.1 1.2 0.1 2.3 4.4 1.2 0.0 13.8 0.2 0.6 3.8 0.0 0.1 0.0 3.9 6.8 0.0 4.0 3.3 19.4 8.8 0.0 0.6 0.7 1.5 3.4 0.3 39.2 6.5 0.6 2.5 0.0 143.2 10.1 0.5 2.2 49.7 0.1 0.3 4.6 0.1 0.0 7.3 6.6 1.3 15.4 6.8 12.5 0.2 1.8 0.8 0.2 1.8 6.3 0.3 CAB39L "bA103J18.3, FLJ12577, MO2L" ENSG00000102547 "Calcium binding protein 39 like" Q9H9S4 13 49308650-49444064 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 200.0" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 41.8;RT4: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003686, HPA045954, HPA076632" Approved Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB003686: AB_426084, HPA045954: AB_2679512, HPA076632: " "unprognostic (3.90e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-1)" "unprognostic (5.01e-1)" "unprognostic (3.29e-1)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (2.94e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (3.08e-2)" "prognostic favorable (7.91e-4)" "prognostic favorable (1.94e-13)" "unprognostic (6.59e-2)" "unprognostic (8.31e-2)" "unprognostic (4.96e-2)" "unprognostic (8.05e-3)" 23.7 37.4 25.0 4.4 26.4 2.2 37.3 21.0 20.7 14.5 68.2 57.7 6.0 15.3 16.3 31.2 18.3 16.5 22.0 24.6 38.7 14.0 5.3 19.5 4.2 24.6 35.0 21.5 12.0 29.2 8.4 12.4 25.1 41.4 11.6 14.8 16.9 22.5 7.5 16.1 12.5 11.5 27.4 4.0 27.1 33.4 31.4 9.4 9.7 13.0 5.2 26.5 17.3 28.4 1.6 1.7 9.8 2.8 9.3 8.7 14.8 9.3 17.9 5.9 4.1 41.8 6.0 14.2 1.2 6.5 6.5 3.4 5.4 6.2 10.2 4.7 4.5 3.7 2.0 2.6 5.2 3.3 1.6 6.4 4.8 4.4 6.8 7.3 8.0 2.2 0.7 3.2 8.1 2.8 3.2 2.4 7.6 5.4 2.7 2.8 1.3 2.3 8.3 43.4 1.2 3.7 5.1 11.8 12.1 11.8 18.4 4.9 7.6 2.5 2.7 5.3 7.6 2.5 2.3 16.3 2.8 2.5 5.7 6.7 2.6 5.4 2.6 2.4 2.0 2.7 3.2 3.4 2.6 1.6 2.3 2.3 5.6 1.9 2.1 0.4 3.6 2.3 25.0 26.4 21.0 20.7 24.6 38.7 24.6 35.0 25.1 27.4 31.4 28.4 6.9 16.0 11.9 52.2 2.4 3.1 12.6 6.6 7.4 6.4 27.1 14.4 14.5 4.3 13.4 11.0 6.2 26.4 3.1 3.9 11.7 10.1 200.0 8.3 9.2 5.4 2.4 1.7 45.0 10.6 14.0 42.5 5.6 3.7 4.5 4.2 3.9 1.9 6.4 1.7 32.4 2.4 16.2 3.5 4.7 32.1 15.5 5.0 12.4 24.4 5.6 14.9 7.2 50.3 43.3 10.3 2.0 11.7 4.6 16.7 0.8 5.0 17.7 5.2 6.6 9.4 16.8 46.0 5.0 16.0 4.4 29.0 3.6 3.9 2.3 21.7 CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 258.2;Glandular and luminal cells: 54.3;Oligodendrocyte precursor cells: 163.3" "Cancer enriched" "Detected in all" 5 "melanoma: 38.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "SK-MEL-30: 154.3;U-266/70: 216.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073649 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA073649: AB_2732233" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "prognostic favorable (4.71e-6)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (4.80e-2)" "unprognostic (7.81e-2)" 17.1 3.3 63.9 2.1 67.9 2.6 13.8 36.8 54.8 6.9 17.1 5.2 7.5 9.4 3.2 6.9 10.9 5.2 4.6 44.9 53.5 13.1 9.9 21.5 2.8 39.6 59.0 3.7 3.0 21.9 4.0 10.4 40.8 3.7 5.1 8.0 22.3 4.5 1.5 17.2 6.7 6.6 31.2 3.7 14.5 3.5 70.2 4.9 15.0 1.8 2.3 5.4 7.8 33.3 13.1 14.4 11.8 0.9 7.1 0.3 20.4 3.1 17.3 4.2 2.5 9.5 23.0 0.7 13.3 14.9 42.3 11.4 9.0 2.3 3.2 0.3 19.4 1.0 38.7 37.1 6.2 2.5 1.0 4.2 2.1 5.3 6.1 26.8 47.1 2.3 0.5 16.2 11.7 30.2 0.1 8.8 7.5 64.5 46.6 3.1 42.2 50.6 21.2 31.5 11.2 8.2 26.1 32.5 154.3 8.3 52.4 7.2 79.3 47.9 0.5 1.6 3.8 216.0 88.9 27.4 0.2 19.2 16.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 63.9 67.9 36.8 54.8 44.9 53.5 39.6 59.0 40.8 31.2 70.2 33.3 2.9 22.4 27.4 258.2 3.8 5.1 2.0 1.4 5.2 4.1 9.2 6.7 1.4 7.2 2.3 3.7 29.2 0.9 1.3 8.5 1.9 1.1 2.0 11.6 4.4 6.0 3.5 1.3 19.2 2.3 1.1 4.1 10.2 54.3 0.0 14.8 25.0 9.3 16.6 0.0 22.2 4.6 0.0 3.5 3.1 3.5 0.0 4.7 28.4 41.2 0.0 1.4 0.0 163.3 1.4 2.4 5.2 6.0 3.6 0.6 6.7 14.3 1.8 18.7 0.0 5.0 2.1 0.2 3.2 1.6 6.7 0.3 1.4 0.5 2.1 2.2 CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 182.3;Inhibitory neurons: 36.0" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 192.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles NA NA 9700000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA034771: AB_10603555, HPA071829: AB_2686454" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" 1.0 0.6 4.7 1.3 5.2 1.2 1.2 9.9 6.9 1.4 0.3 1.6 1.2 1.6 0.9 0.6 1.1 0.7 8.4 0.7 13.9 2.3 0.3 49.1 1.2 8.3 8.4 2.1 4.3 2.5 7.1 1.8 14.0 3.0 1.9 8.6 1.3 1.1 1.8 2.6 1.6 1.2 4.8 1.4 4.1 6.5 11.4 1.0 2.2 1.5 0.5 0.5 0.7 2.1 0.0 0.1 3.0 6.6 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.0 0.6 0.2 24.8 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.4 0.0 1.1 0.1 0.2 7.9 0.2 0.5 0.2 0.0 0.7 0.0 0.0 18.6 192.7 0.6 0.4 0.0 5.5 1.5 0.0 0.0 0.1 1.8 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.9 0.7 0.9 0.7 0.0 0.5 1.2 0.7 0.0 0.9 0.0 0.1 1.2 0.4 4.7 5.2 9.9 6.9 0.7 13.9 8.3 8.4 14.0 4.8 11.4 2.1 0.4 76.9 182.3 4.2 0.4 1.5 0.4 0.0 1.8 21.5 2.5 1.7 4.6 0.0 2.5 1.8 20.9 0.0 6.8 0.8 0.0 0.2 0.7 0.1 0.4 0.6 1.2 2.7 7.8 0.0 0.0 1.5 3.1 0.2 20.3 0.3 0.4 0.0 0.1 0.0 36.0 11.0 0.0 0.0 0.4 4.0 0.3 0.4 0.0 1.9 0.1 4.3 15.5 6.0 0.9 0.4 0.3 1.9 2.9 0.7 0.2 0.7 2.2 9.8 13.1 2.4 2.4 2.6 11.2 0.2 0.6 0.3 2.9 3.4 0.6 0.3 CACNB3 CACNLB3 ENSG00000167535 "Calcium voltage-gated channel auxiliary subunit beta 3" P54284 12 48813794-48828941 "FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.9;U-937: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059515 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus, Vesicles" "HPA059515: AB_2684047" "unprognostic (1.77e-2)" "unprognostic (4.84e-2)" "unprognostic (2.16e-3)" "unprognostic (2.12e-2)" "unprognostic (8.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.06e-1)" "unprognostic (3.60e-2)" "unprognostic (3.27e-2)" "unprognostic (2.24e-1)" "unprognostic (5.67e-3)" "unprognostic (1.04e-1)" "unprognostic (5.44e-3)" "unprognostic (6.31e-3)" "unprognostic (6.58e-2)" "unprognostic (1.98e-1)" "unprognostic (2.78e-3)" 10.1 3.9 67.9 2.8 69.9 1.3 9.0 56.8 84.2 33.7 44.1 18.1 4.1 31.1 8.5 21.5 19.6 7.2 8.4 72.6 56.7 12.4 1.9 11.8 1.8 50.2 56.2 43.7 4.5 5.1 12.3 5.8 53.4 13.7 8.2 4.7 13.0 9.1 2.8 11.5 10.8 23.1 49.9 6.1 9.2 8.6 59.6 7.6 9.6 5.9 4.1 14.5 20.2 58.7 17.3 13.2 21.1 46.1 26.8 18.0 12.9 16.8 39.4 25.6 14.5 4.5 13.4 2.2 21.5 30.7 4.4 17.2 21.6 19.5 10.1 18.4 5.9 8.5 11.7 0.6 11.0 1.7 9.1 11.7 10.6 10.2 5.5 75.9 31.1 18.6 1.2 7.2 16.9 42.6 22.1 2.2 13.3 18.1 10.9 24.0 5.0 6.6 19.9 31.6 32.9 31.8 5.5 37.1 12.0 18.6 25.2 7.7 27.3 15.5 21.7 7.7 9.5 7.1 3.5 0.7 12.9 109.9 5.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.6 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.2 67.9 69.9 56.8 84.2 72.6 56.7 50.2 56.2 53.4 49.9 59.6 58.7 5.6 3.2 4.3 1.0 0.5 2.9 3.2 5.9 4.0 3.2 8.7 5.7 2.8 1.5 5.1 1.8 4.2 0.8 2.1 12.6 1.9 9.5 1.0 10.0 22.0 5.9 10.2 0.8 15.1 4.3 10.4 7.9 6.1 7.1 1.3 12.0 3.6 0.2 1.6 0.0 4.5 9.5 16.2 0.6 2.9 2.7 13.4 2.4 1.8 3.7 3.7 1.0 2.1 2.0 1.1 10.4 4.6 10.9 1.3 2.9 8.7 0.7 9.4 1.0 0.0 1.5 12.2 1.6 8.1 9.6 5.1 1.1 3.5 6.1 14.4 1.9 CCDC85A KIAA1912 ENSG00000055813 "Coiled-coil domain containing 85A" Q96PX6 2 56183990-56386172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3" "Cell type enhanced" "Detected in some" "Adipocytes: 57.7;Excitatory neurons: 228.7;Inhibitory neurons: 160.5;Microglial cells: 60.0" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 45.9;fHDF/TERT166: 74.5;U-266/70: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043106, HPA057020" Uncertain "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043106: AB_10794770, HPA057020: AB_2683311" "unprognostic (2.29e-1)" "unprognostic (1.28e-1)" "unprognostic (6.87e-2)" "unprognostic (3.66e-2)" "unprognostic (7.87e-2)" "unprognostic (7.62e-2)" "unprognostic (3.07e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.55e-5)" "unprognostic (3.28e-2)" "unprognostic (1.00e-1)" "unprognostic (2.88e-2)" "unprognostic (1.83e-2)" 12.5 0.6 5.4 0.6 7.4 0.0 3.5 1.2 8.0 2.5 0.0 0.7 0.3 6.3 0.8 0.7 2.1 1.2 4.5 6.9 7.2 1.0 0.1 5.5 0.5 17.3 6.5 0.5 0.7 1.3 0.2 10.0 7.0 2.0 0.7 4.0 1.2 2.7 5.4 1.7 0.4 4.7 11.8 0.7 0.5 0.4 5.1 0.6 9.1 7.5 0.6 0.7 0.7 15.2 0.0 0.8 0.1 0.0 13.9 0.8 0.0 11.6 1.1 9.8 0.9 0.0 0.1 45.9 1.7 74.5 0.0 2.0 0.0 0.0 5.6 0.0 0.3 0.0 0.6 0.0 0.7 0.0 0.1 3.3 0.3 0.0 1.2 5.5 9.7 0.0 0.0 6.1 1.3 0.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 1.7 1.3 0.0 0.3 0.1 0.0 2.1 5.3 0.0 15.3 7.9 2.3 0.1 0.9 32.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 7.4 1.2 8.0 6.9 7.2 17.3 6.5 7.0 11.8 5.1 15.2 57.7 25.6 0.6 15.3 0.8 3.3 0.5 0.0 0.0 7.8 0.6 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.3 3.6 0.2 1.9 14.8 1.2 0.0 228.7 0.4 0.1 3.7 0.0 0.5 0.0 0.2 8.6 0.0 2.3 0.0 160.5 0.2 0.0 0.3 2.0 11.9 0.3 0.3 5.4 60.0 0.0 0.7 0.0 33.7 7.2 0.7 0.1 0.0 0.1 0.3 0.0 0.3 0.0 1.5 0.0 10.0 2.7 0.2 0.8 0.1 1.3 0.1 0.1 3.6 0.9 0.3 CDC42BPB "KIAA1124, MRCKB" ENSG00000198752 "CDC42 binding protein kinase beta" Q9Y5S2 14 102932380-103057549 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022821 Approved NA NA 12000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA022821: AB_1846376" "unprognostic (6.73e-2)" "unprognostic (2.19e-2)" "unprognostic (6.99e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "unprognostic (3.46e-2)" "unprognostic (2.28e-1)" "prognostic favorable (8.67e-10)" "unprognostic (2.11e-1)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (7.56e-2)" 38.7 31.3 42.7 17.8 42.5 3.6 31.2 31.2 40.2 33.5 21.0 35.8 30.2 38.0 17.9 37.8 31.3 29.5 36.3 44.3 36.4 32.3 28.9 32.9 9.8 38.6 40.2 33.4 33.1 34.2 32.5 29.5 35.7 28.7 20.2 24.1 27.9 30.4 27.2 33.0 34.9 32.3 38.5 22.2 32.0 25.2 40.8 8.6 29.6 24.2 12.6 35.0 33.2 46.1 42.8 83.8 52.7 38.7 57.3 65.1 53.0 47.9 50.3 49.7 45.4 28.8 49.0 0.0 51.1 93.7 37.7 53.0 54.9 57.2 52.3 52.2 24.8 23.4 68.0 29.0 62.2 0.2 24.1 56.7 57.6 51.0 48.5 52.2 97.7 9.8 19.3 11.7 48.3 89.2 0.4 5.4 25.3 66.5 68.4 0.2 44.3 1.2 63.1 82.6 38.2 41.6 85.1 31.6 35.8 55.7 48.7 14.9 125.3 47.3 31.6 105.8 45.3 15.1 17.4 12.4 53.2 5.2 46.9 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.7 42.5 31.2 40.2 44.3 36.4 38.6 40.2 35.7 38.5 40.8 46.1 57.1 57.7 35.8 37.5 7.8 14.5 16.5 14.5 17.6 45.8 19.1 15.4 28.8 28.6 27.4 55.2 33.3 12.6 0.5 35.4 3.9 29.8 14.2 35.8 55.0 46.3 25.2 11.0 40.3 21.8 11.1 25.7 32.1 59.4 13.3 37.8 36.0 20.5 12.8 57.2 33.1 16.1 30.5 13.5 14.7 7.9 32.3 21.7 12.4 31.9 11.1 29.3 0.0 31.7 74.6 44.2 15.4 55.3 3.5 26.1 28.2 15.4 28.1 42.3 6.6 38.6 29.3 15.5 17.0 27.2 18.3 16.8 3.2 37.3 27.5 32.4 CDC42EP2 "BORG1, CEP2" ENSG00000149798 "CDC42 effector protein 2" O14613 11 65314866-65322417 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 50.5;Langerhans cells: 77.7;Pancreatic endocrine cells: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 50.4;intermediate monocyte: 118.8;neutrophil: 171.5;non-classical monocyte: 88.5" "Group enriched" "Detected in many" 15 "granulocytes: 171.5;monocytes: 118.8" "Cell line enhanced" "Detected in many" "HHSteC: 51.5;PC-3: 61.0;U-2197: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038562 Approved Supported Microtubules,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Microtubules, Cytosol" "HPA038562: AB_10671745" "unprognostic (1.69e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (4.73e-3)" "prognostic unfavorable (2.89e-5)" "prognostic unfavorable (6.66e-4)" "unprognostic (1.01e-1)" "unprognostic (5.36e-2)" "unprognostic (8.57e-3)" "unprognostic (3.81e-1)" "unprognostic (1.68e-1)" "unprognostic (2.66e-2)" "unprognostic (3.67e-2)" "unprognostic (2.89e-2)" "unprognostic (1.89e-2)" 42.1 5.7 15.4 7.7 25.1 0.4 23.1 20.7 20.0 13.9 5.8 15.4 9.1 16.6 1.7 7.7 15.3 15.2 22.4 15.7 17.0 15.3 4.1 19.1 1.8 24.9 23.6 10.8 5.8 0.6 5.0 11.6 22.3 10.2 1.6 1.9 4.9 4.5 6.6 5.6 13.0 6.8 17.5 18.4 14.5 2.1 21.4 0.4 16.8 5.6 1.2 18.6 9.4 44.3 7.1 6.6 0.9 4.3 14.6 26.4 1.3 7.4 28.8 5.5 6.2 19.8 16.7 0.5 20.9 19.9 2.0 8.9 2.5 26.0 1.2 1.0 3.8 1.3 12.8 14.8 51.5 0.4 0.5 11.5 2.7 20.3 28.8 4.5 22.4 1.0 2.6 4.3 7.1 10.7 0.8 1.6 3.7 18.5 61.0 0.8 0.7 0.5 19.5 4.9 0.5 1.7 18.0 14.7 1.1 0.7 2.5 0.4 30.6 6.7 5.6 55.9 3.1 0.1 1.7 0.6 11.2 0.3 2.7 0.0 50.4 2.1 0.1 118.8 0.1 1.2 0.0 0.1 9.9 0.0 0.1 0.0 171.5 0.0 88.5 0.4 0.0 17.8 15.4 25.1 20.7 20.0 15.7 17.0 24.9 23.6 22.3 17.5 21.4 44.3 25.8 0.0 0.0 0.0 1.5 12.7 11.0 25.8 6.8 15.3 12.1 6.3 6.3 2.8 17.0 12.9 0.0 0.5 1.6 10.0 3.9 50.5 0.5 6.0 11.6 36.4 1.8 2.7 0.6 40.3 3.5 32.3 9.7 11.1 5.7 1.5 26.7 0.9 1.3 3.3 0.4 8.0 8.2 18.7 77.7 1.9 18.6 33.3 12.4 1.0 18.3 1.0 0.0 0.0 10.6 65.1 15.6 13.5 1.8 7.4 21.2 3.7 6.3 5.3 39.5 16.6 16.2 1.7 3.4 4.8 10.1 1.6 1.4 1.8 8.4 36.4 CDC42EP4 "BORG4, CEP4, KAIA1777, MGC17125, MGC3740" ENSG00000179604 "CDC42 effector protein 4" Q9H3Q1 17 73283624-73312005 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Horizontal cells: 753.7;Muller glia cells: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023335, HPA024797" Approved Supported Supported "Plasma membrane,Actin filaments,Microtubules" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Microtubules" "Plasma membrane" "HPA023335: AB_10603783, HPA024797: AB_10600696" "unprognostic (8.76e-2)" "unprognostic (4.38e-3)" "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (6.29e-2)" "unprognostic (9.01e-3)" "unprognostic (2.44e-3)" "unprognostic (1.08e-1)" "unprognostic (8.00e-2)" "unprognostic (2.41e-1)" "unprognostic (4.16e-2)" "unprognostic (6.73e-2)" "unprognostic (3.97e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" 94.5 54.9 84.9 15.3 84.7 14.9 74.5 90.6 76.3 47.4 75.0 55.6 35.7 52.7 60.1 33.3 69.4 19.1 50.5 82.2 103.1 28.6 32.2 38.6 16.1 141.9 104.5 70.7 77.5 20.5 45.0 22.9 83.7 38.7 17.4 98.1 41.5 43.1 28.8 40.6 36.0 25.5 103.5 24.1 42.4 20.5 105.9 20.2 45.4 18.8 27.6 33.8 39.5 109.5 30.1 70.1 24.7 20.9 48.8 40.5 65.0 26.2 32.6 24.3 17.9 14.8 42.1 0.1 22.9 31.6 27.6 20.6 17.2 18.0 14.6 1.4 17.0 6.7 35.2 34.7 24.3 1.1 7.3 51.4 14.9 21.2 10.5 19.2 27.9 0.6 18.9 1.4 14.9 23.2 1.2 8.6 13.5 87.8 48.4 0.8 11.0 3.1 28.8 34.3 16.4 24.8 19.7 53.1 18.4 19.0 64.3 9.8 28.7 22.7 47.6 18.1 18.9 1.4 1.2 0.2 37.3 4.7 60.7 3.3 3.2 5.9 0.1 8.5 0.2 0.1 0.0 0.0 4.3 0.0 0.2 0.0 5.4 0.3 20.1 0.1 0.0 2.1 84.9 84.7 90.6 76.3 82.2 103.1 141.9 104.5 83.7 103.5 105.9 109.5 117.1 12.8 15.6 54.9 2.8 48.7 58.5 54.9 97.9 11.5 45.8 37.1 10.8 31.5 29.1 12.9 6.2 32.1 2.5 47.3 11.7 29.4 0.6 29.7 47.6 43.8 31.2 9.1 1.0 43.6 35.0 46.1 31.1 41.2 13.3 19.6 42.8 27.7 6.1 753.7 1.3 41.3 14.2 5.5 30.1 2.7 18.3 9.1 30.2 6.5 11.1 570.4 0.0 2.5 2.5 30.4 33.5 15.4 2.5 42.6 53.1 8.0 18.0 26.2 131.5 98.0 69.9 1.1 2.0 83.2 44.9 84.3 6.0 13.6 30.2 124.1 CDH24 CDH11L ENSG00000139880 "Cadherin 24" Q86UP0 14 23047062-23057538 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 11.7;Astrocytes: 9.1;Bipolar cells: 8.2;Endothelial cells: 8.8;Enteroendocrine cells: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 52.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074551 Approved Vesicles,Cytosol NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA074551: " "unprognostic (2.30e-1)" "unprognostic (3.06e-2)" "unprognostic (4.15e-3)" "unprognostic (6.21e-2)" "unprognostic (1.27e-1)" "unprognostic (9.18e-2)" "unprognostic (6.68e-3)" "unprognostic (2.71e-2)" "unprognostic (5.97e-3)" "unprognostic (3.55e-1)" "unprognostic (4.18e-2)" "unprognostic (5.97e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.37e-2)" "unprognostic (8.85e-2)" 4.3 2.4 4.9 1.2 3.8 1.2 3.6 3.8 4.7 5.9 1.7 2.7 1.1 8.6 1.1 4.0 4.3 4.2 2.0 9.4 4.3 2.9 0.5 3.3 1.3 4.0 3.9 2.4 2.1 2.2 1.9 1.6 3.9 3.1 1.7 1.7 3.1 1.6 0.7 2.9 2.4 4.0 2.3 2.4 2.0 1.7 3.8 3.7 4.6 0.5 0.9 2.6 4.1 5.3 4.6 4.5 18.3 20.9 4.4 2.2 10.1 8.4 5.4 7.0 9.0 5.7 6.1 0.3 6.7 9.2 1.8 25.8 8.0 7.1 5.6 7.1 6.7 1.0 12.7 1.9 4.9 13.2 0.3 17.3 2.3 7.6 5.0 8.5 11.5 4.2 2.9 11.0 6.1 12.9 1.0 8.8 4.6 4.7 10.2 22.9 6.1 8.4 2.0 3.8 52.9 14.2 19.7 10.4 1.1 5.0 9.3 1.9 10.7 6.9 26.0 2.8 6.3 3.5 1.1 0.3 7.2 3.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 3.8 3.8 4.7 9.4 4.3 4.0 3.9 3.9 2.3 3.8 5.3 11.7 0.0 0.0 9.1 0.3 1.5 0.8 0.5 3.4 8.2 2.1 1.1 2.0 0.0 0.5 1.8 0.0 2.3 0.9 1.9 1.9 0.5 0.4 0.6 2.1 8.8 10.7 0.0 2.6 0.5 2.5 1.7 1.1 1.0 0.0 4.3 2.5 0.0 0.6 0.0 1.7 1.7 0.0 0.0 0.3 1.0 0.0 0.1 1.8 2.8 0.1 4.4 0.0 5.5 0.2 0.6 0.3 0.0 0.3 0.8 0.2 0.5 0.5 0.8 0.0 0.2 1.5 1.1 2.5 2.0 2.3 1.9 0.7 2.5 2.1 0.9 CDK2AP1 "doc-1, DOC1, DORC1, p12DOC-1, ST19" ENSG00000111328 "Cyclin dependent kinase 2 associated protein 1" O14519 12 123250112-123272334 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 44.3;intermediate monocyte: 152.6;myeloid DC: 52.5;non-classical monocyte: 175.4" "Group enriched" "Detected in many" 5 "dendritic cells: 52.5;monocytes: 175.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019377, HPA057648, HPA068833" Approved Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB019377: , HPA057648: AB_2683488, HPA068833: AB_2686046" "unprognostic (1.56e-1)" "unprognostic (5.94e-2)" "unprognostic (1.83e-2)" "unprognostic (3.04e-2)" "unprognostic (7.77e-2)" "unprognostic (8.89e-2)" "unprognostic (4.21e-3)" "unprognostic (2.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.70e-2)" "unprognostic (3.32e-2)" "unprognostic (2.22e-1)" "prognostic unfavorable (5.27e-7)" "unprognostic (9.32e-2)" "unprognostic (6.20e-2)" "unprognostic (5.56e-2)" "unprognostic (1.18e-1)" 96.1 82.8 239.4 62.7 255.4 70.6 105.0 270.5 285.1 114.8 199.5 111.8 40.1 111.9 127.7 115.1 81.5 87.7 95.1 238.3 272.2 82.2 56.7 78.3 51.0 296.1 256.0 56.0 53.2 72.3 88.8 64.4 288.2 103.5 63.1 43.4 158.8 97.7 91.5 68.1 53.9 120.3 292.7 48.6 84.9 69.1 260.8 86.0 61.4 109.9 56.5 124.9 105.3 288.3 125.7 172.4 451.1 481.5 352.6 443.9 81.8 399.1 369.6 311.1 234.7 131.0 117.5 0.1 174.9 611.4 115.9 111.3 484.0 261.3 256.1 77.6 120.7 66.4 98.0 208.4 192.0 104.9 68.7 282.8 267.0 180.2 116.9 283.4 449.4 151.0 90.6 0.5 594.9 244.3 140.3 170.2 296.1 154.9 129.2 528.7 193.0 54.0 259.7 295.2 416.7 496.5 290.9 141.5 412.0 119.4 272.5 104.3 273.2 286.5 149.1 172.9 267.6 21.0 41.6 116.1 156.6 48.9 640.9 15.9 44.3 21.3 0.5 152.6 1.9 0.9 0.5 0.9 52.5 0.1 0.3 0.5 1.5 1.3 175.4 4.2 0.4 29.7 239.4 255.4 270.5 285.1 238.3 272.2 296.1 256.0 288.2 292.7 260.8 288.3 10.4 28.9 39.7 32.0 3.0 1.3 1.5 8.7 18.2 0.3 6.9 8.8 1.8 8.6 21.7 12.9 0.0 1.6 1.4 12.3 1.9 24.0 30.7 8.0 31.6 14.0 7.7 13.7 12.2 16.7 3.3 13.8 19.9 7.6 19.0 3.2 16.4 6.9 6.0 3.3 5.0 16.7 4.1 26.0 4.9 131.8 13.4 18.8 3.6 14.0 11.4 19.4 1.0 17.1 25.0 24.3 12.5 14.3 2.8 0.4 5.4 3.4 12.5 0.3 0.0 3.2 10.3 1.4 8.1 46.9 2.8 1.4 1.9 1.0 16.2 0.9 CH25H ENSG00000138135 "Cholesterol 25-hydroxylase" O95992 10 89205629-89207317 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.3" "Cell type enhanced" "Detected in many" "Adipocytes: 125.9;Basal squamous epithelial cells: 224.3;Macrophages: 47.3;Microglial cells: 40.3;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 8.8;ASC TERT1: 4.4;fHDF/TERT166: 32.8;HSkMC: 8.2" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "spinal cord: 6.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "unprognostic (6.07e-3)" "unprognostic (2.96e-3)" "unprognostic (1.57e-1)" "unprognostic (5.11e-2)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "unprognostic (8.65e-3)" "unprognostic (7.74e-2)" "unprognostic (4.76e-2)" "unprognostic (2.62e-5)" "unprognostic (2.47e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-2)" "unprognostic (2.29e-2)" 21.5 5.1 4.3 7.0 5.0 3.1 7.4 6.5 6.6 3.5 4.4 3.6 3.2 1.3 12.6 14.7 6.0 14.6 4.5 4.2 8.4 7.8 3.6 17.2 4.0 18.4 9.5 2.1 1.6 1.1 9.0 4.2 11.4 4.1 5.5 0.4 2.1 1.3 1.8 3.0 5.6 5.5 8.6 2.0 5.8 0.1 6.0 35.3 2.8 1.0 3.7 18.5 2.1 8.2 0.0 0.0 0.0 0.0 8.8 4.4 0.0 0.1 3.1 0.8 0.9 0.0 0.0 0.0 1.1 32.8 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.8 0.0 0.0 8.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 4.2 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.0 6.5 6.6 4.2 8.4 18.4 9.5 11.4 8.6 6.0 8.2 125.9 3.2 3.4 0.3 1.8 6.9 4.4 11.7 224.3 0.0 6.4 1.0 0.6 0.0 10.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 1.5 0.9 23.6 0.0 0.0 2.9 0.0 0.2 33.4 2.0 3.1 1.3 0.0 2.5 0.0 10.2 1.7 0.5 0.0 2.0 12.9 8.2 0.0 0.3 47.3 7.2 40.3 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.7 4.4 1.0 0.0 0.0 4.5 0.5 6.6 3.6 59.3 0.0 0.0 30.8 6.7 0.1 11.6 0.5 0.0 6.2 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 694.7;intestine: 653.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 2767.4;Distal enterocytes: 4691.8;Distal tubular cells: 2281.3;Horizontal cells: 5042.4;Muller glia cells: 3639.8;Rod photoreceptor cells: 3789.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 290.8" "Lineage enriched" "Detected in many" 18 "monocytes: 290.8" "Cell line enhanced" "Detected in many" "CACO-2: 455.8;HEK 293: 1399.8;SCLC-21H: 792.2;SH-SY5Y: 352.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favorable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 90.7 60.0 471.6 25.8 627.0 3.2 47.2 641.1 694.7 105.2 192.7 653.4 36.0 222.6 16.0 54.5 197.9 17.9 269.8 428.7 482.3 161.0 9.0 60.3 4.0 427.5 440.4 58.8 27.7 108.2 74.0 4.7 345.1 301.8 151.9 471.3 37.9 208.3 80.0 76.5 120.8 113.8 434.5 6.8 479.9 97.6 596.2 2.8 87.9 47.1 5.1 298.4 101.6 383.6 2.4 54.5 321.1 14.7 4.4 2.3 6.3 37.5 0.3 2.4 1.4 455.8 7.3 0.4 36.9 29.1 9.9 70.2 109.9 1.5 0.2 9.6 1399.8 111.0 242.1 165.4 16.6 0.7 87.9 14.7 0.6 3.9 0.8 3.3 0.0 5.1 198.7 3.7 4.8 20.0 2.3 3.9 109.1 48.3 213.6 13.9 6.8 275.9 65.9 2.5 792.2 352.2 65.3 10.6 25.2 21.6 21.1 40.9 2.2 1.5 56.3 4.7 147.3 21.1 2.7 7.2 6.4 2.1 14.1 2.4 0.5 14.6 0.3 28.5 0.4 0.0 0.2 0.1 16.4 0.2 0.1 0.5 1.0 0.2 290.8 0.0 0.7 6.0 471.6 627.0 641.1 694.7 428.7 482.3 427.5 440.4 345.1 434.5 596.2 383.6 14.8 195.5 103.5 515.8 13.5 153.7 296.2 257.6 56.3 2767.4 41.5 48.9 553.5 145.8 117.9 114.0 1909.9 4.4 3.4 4691.8 2281.3 127.6 445.8 773.2 205.7 60.8 467.1 9.9 178.0 42.5 11.7 96.6 359.4 408.5 28.6 476.1 74.6 9.2 8.2 5042.4 147.0 726.0 187.2 2.8 44.9 147.4 304.1 39.8 181.5 88.1 74.2 3639.8 0.0 93.5 161.2 131.4 1996.9 1089.3 6.6 279.8 9.5 118.0 456.1 3789.9 59.2 15.4 222.6 127.3 97.4 22.1 175.2 41.6 19.1 12.2 755.6 220.1 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 CLIP3 "CLIPR-59, RSNL1" ENSG00000105270 "CAP-Gly domain containing linker protein 3" Q96DZ5 19 36014660-36033343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.9;Excitatory neurons: 24.8;Granulosa cells: 25.7;Horizontal cells: 42.1;Inhibitory neurons: 30.7;Muller glia cells: 26.9;Peritubular cells: 24.5" "Cancer enhanced" "Detected in all" "glioma: 65.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 83.3;fHDF/TERT166: 61.5;HSkMC: 93.1;hTERT-RPE1: 80.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079430 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA079430: " "unprognostic (1.91e-2)" "unprognostic (8.70e-2)" "unprognostic (1.16e-2)" "unprognostic (5.01e-2)" "unprognostic (1.19e-1)" "unprognostic (1.38e-1)" "unprognostic (3.60e-2)" "unprognostic (2.92e-2)" "unprognostic (2.55e-2)" "unprognostic (3.26e-2)" "prognostic favorable (2.80e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (1.56e-10)" "unprognostic (6.31e-3)" "unprognostic (1.52e-1)" "unprognostic (9.63e-2)" "unprognostic (1.09e-2)" 16.4 13.5 109.8 9.7 117.0 0.5 14.0 92.0 142.5 50.9 0.3 75.3 6.5 66.2 12.7 16.3 35.7 23.5 12.7 122.5 121.5 11.5 2.9 10.0 7.0 105.2 158.4 48.6 3.6 2.6 46.9 9.3 140.0 29.2 8.6 54.9 6.3 33.4 3.4 7.8 21.4 37.9 60.3 9.9 25.7 12.0 92.6 9.4 5.5 3.5 6.2 68.2 32.4 106.2 1.3 3.8 33.0 1.4 53.8 83.3 1.1 19.1 45.9 15.6 23.4 4.0 1.3 1.8 7.6 61.5 1.3 1.6 0.6 0.2 11.1 2.4 1.3 1.0 4.1 0.8 54.1 1.0 1.0 93.1 0.9 13.4 0.3 80.8 17.7 13.0 1.9 3.5 35.2 2.9 18.6 1.3 4.0 1.3 0.9 2.4 0.6 1.1 0.5 1.2 32.2 37.6 2.2 0.8 1.0 13.5 1.2 0.4 4.9 26.8 21.9 1.3 1.2 2.8 2.5 1.4 41.1 1.8 10.2 0.0 0.1 0.3 0.2 0.2 0.0 0.2 0.3 0.1 0.0 0.1 0.3 0.2 0.1 0.4 0.0 0.1 0.2 0.1 109.8 117.0 92.0 142.5 122.5 121.5 105.2 158.4 140.0 60.3 92.6 106.2 1.1 0.0 0.0 11.4 0.1 0.6 0.6 0.5 0.6 30.9 0.4 4.3 4.3 0.0 0.1 1.8 2.1 0.6 0.0 0.3 0.0 0.1 11.3 0.7 15.3 3.6 2.4 0.0 24.8 0.2 0.5 16.1 1.1 0.7 0.0 25.7 5.0 0.2 0.8 42.1 30.7 0.9 0.0 0.3 2.3 19.2 22.1 0.5 3.6 10.3 0.0 26.9 0.0 14.6 15.3 0.3 0.0 24.5 0.2 0.4 0.3 0.3 0.7 13.7 6.6 8.7 12.8 2.3 3.5 0.5 1.3 1.2 0.6 2.9 0.2 0.1 CNN3 ENSG00000117519 "Calponin 3" Q15417 1 94896949-94927223 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "glioma: 315.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 10.5;naive CD4 T-cell: 11.6" "Group enriched" "Detected in many" 12 "B-cells: 10.5;T-cells: 11.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009849, HPA051237" Enhanced Enhanced "Actin filaments,Cytosol" NA NA 660000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "CAB009849: AB_2276410, HPA051237: AB_2681399" "unprognostic (8.47e-2)" "unprognostic (5.19e-2)" "unprognostic (5.22e-2)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-2)" "unprognostic (8.87e-2)" "unprognostic (5.20e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-3)" "unprognostic (2.33e-2)" "unprognostic (8.71e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.99e-4)" 163.9 255.6 152.7 78.9 153.7 2.1 160.0 148.6 186.3 164.8 147.7 142.4 135.9 214.0 71.0 149.7 147.1 152.3 127.6 151.7 189.9 245.1 143.7 209.0 51.4 197.4 170.9 153.1 83.3 53.1 101.7 256.0 173.1 126.2 82.8 125.0 125.5 133.7 26.3 62.5 100.0 196.0 180.8 94.1 111.8 50.2 164.5 55.1 125.0 52.6 44.3 156.5 166.2 174.0 416.6 77.9 429.0 380.1 286.0 264.2 191.7 197.2 381.3 319.4 511.2 348.7 35.6 0.1 436.6 243.4 315.7 116.2 307.2 169.9 428.1 1.6 113.0 18.8 47.5 256.2 545.0 0.2 0.8 246.2 25.5 394.1 89.4 539.6 282.8 26.7 4.1 35.3 798.9 0.2 19.8 0.9 333.6 0.3 43.3 0.6 524.2 1.8 392.9 156.6 26.3 264.2 163.0 65.0 272.8 301.7 124.8 38.5 182.4 212.2 364.9 80.2 647.0 43.9 27.2 1.5 46.0 0.6 327.1 0.2 0.0 0.0 2.2 0.1 3.4 4.6 2.1 1.2 0.1 10.5 11.6 8.3 0.4 0.9 0.1 0.0 0.0 2.6 152.7 153.7 148.6 186.3 151.7 189.9 197.4 170.9 173.1 180.8 164.5 174.0 183.5 150.6 80.7 82.9 18.1 78.3 435.7 232.3 48.9 11.9 122.2 64.1 42.2 88.6 156.2 126.9 20.9 236.1 3.2 36.0 436.3 275.1 156.1 77.4 151.1 278.3 72.4 20.0 12.9 240.7 40.9 287.8 33.1 104.9 14.0 164.4 373.0 152.1 22.6 1.7 16.9 58.7 429.3 20.1 56.3 150.7 274.6 9.3 197.5 29.0 4.7 394.6 0.0 62.4 22.7 130.8 53.2 382.1 2.6 319.1 117.9 518.5 95.1 14.4 263.0 399.8 374.9 10.8 34.7 91.4 77.7 205.8 14.9 214.5 131.0 327.4 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Astrocytes: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 38.9;BJ: 23.6;BJ hTERT+: 26.2;BJ hTERT+ SV40 Large T+: 14.4;HSkMC: 28.2;WM-115: 26.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" 47.4 5.0 33.2 9.9 33.2 0.1 32.3 30.6 45.9 44.9 43.6 19.3 3.7 27.3 1.9 9.0 22.8 4.1 33.5 33.3 26.4 7.9 13.4 14.2 3.2 35.2 30.2 6.3 5.2 3.0 3.5 32.8 32.3 16.6 2.0 21.1 7.3 8.9 15.3 21.7 11.7 10.3 31.0 1.7 9.9 4.7 30.2 4.5 12.7 6.0 3.9 12.6 26.4 28.4 0.0 0.0 0.5 0.0 12.4 38.9 0.0 23.6 26.2 14.4 5.7 0.0 0.0 0.0 0.2 4.4 0.3 2.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 28.2 0.6 5.2 5.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.1 0.0 0.0 0.0 11.6 5.5 0.5 0.0 0.0 0.0 0.0 1.5 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 33.2 30.6 45.9 33.3 26.4 35.2 30.2 32.3 31.0 30.2 28.4 13.7 0.0 0.0 510.3 0.0 4.2 0.1 0.2 2.2 65.1 0.3 0.9 6.4 0.0 0.1 0.0 6.2 0.1 0.3 1.3 0.0 0.2 6.9 0.4 12.0 8.1 0.0 0.0 15.6 0.0 0.2 17.5 0.5 0.4 0.0 0.0 3.9 22.9 0.6 3.3 3.4 0.0 0.0 0.0 3.2 2.1 17.4 0.4 14.2 36.5 0.1 2.6 0.0 73.9 2.5 0.3 0.1 8.2 0.0 0.3 0.2 0.1 0.9 28.3 92.1 8.5 58.0 0.3 0.3 3.2 7.1 0.1 1.9 0.9 0.0 0.3 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.6;fallopian tube: 38.2;lung: 50.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 119.5;Club cells: 36.4;Inhibitory neurons: 63.6;Oligodendrocyte precursor cells: 54.8" "Cancer enhanced" "Detected in many" "melanoma: 43.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 3.0;HMC-1: 2.5;HUVEC TERT2: 7.1;SCLC-21H: 4.7;SK-MEL-30: 7.7;TIME: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" NA NA 550000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA008175: AB_1847254" "unprognostic (2.55e-1)" "unprognostic (6.41e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.54e-1)" "unprognostic (6.96e-3)" "unprognostic (9.30e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (1.69e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.70e-4)" "unprognostic (1.05e-2)" "unprognostic (3.29e-3)" "prognostic favorable (1.51e-4)" 4.4 0.8 8.7 1.1 23.7 0.0 2.4 10.9 20.1 6.4 0.9 11.5 0.5 1.3 3.8 8.3 38.2 0.3 10.6 9.1 8.1 4.3 0.4 50.0 0.4 45.1 10.2 0.7 1.3 0.8 5.3 0.0 45.6 2.3 0.4 11.3 3.4 33.6 1.1 4.1 2.3 0.8 12.6 0.1 1.8 3.9 18.5 0.2 4.7 1.5 0.3 30.2 4.9 15.5 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 3.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 4.7 1.1 0.5 0.0 7.7 0.3 0.0 0.0 9.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 23.7 10.9 20.1 9.1 8.1 45.1 10.2 45.6 12.6 18.5 15.5 1.9 22.4 119.5 2.9 0.0 1.5 2.7 1.3 5.7 10.1 2.6 2.8 7.1 1.5 36.4 9.2 0.0 0.0 0.1 0.0 0.0 4.6 0.1 0.5 0.1 8.8 1.8 0.0 22.9 0.7 0.0 2.3 0.0 0.6 5.1 0.0 5.7 0.1 0.0 0.0 63.6 0.0 0.0 0.6 0.9 0.6 0.0 0.2 8.8 2.8 0.0 14.1 0.0 54.8 6.2 0.6 0.0 0.4 1.2 1.3 0.0 0.0 0.9 5.3 0.0 3.5 0.3 1.5 1.9 13.1 0.4 0.0 0.4 0.0 0.0 1.7 CRTC3 FLJ21868 ENSG00000140577 "CREB regulated transcription coactivator 3" Q6UUV7 15 90529923-90645345 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043735, HPA063691" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA043735: AB_10794286, HPA063691: AB_2685092" "unprognostic (7.60e-2)" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.51e-1)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (6.48e-2)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (5.22e-3)" "unprognostic (4.67e-2)" "unprognostic (9.32e-2)" "unprognostic (9.51e-2)" "unprognostic (2.30e-1)" 27.0 15.5 16.8 14.2 25.3 10.7 21.7 20.0 19.8 26.3 10.1 28.4 7.3 26.0 10.9 12.5 23.8 14.8 19.8 17.0 16.4 14.5 13.2 23.2 15.8 21.8 23.1 36.8 10.7 13.8 9.9 17.1 21.1 18.8 9.4 13.5 17.4 17.0 19.9 19.1 16.6 20.9 16.3 13.3 15.2 16.8 23.2 15.0 22.3 17.4 15.7 28.4 18.3 31.6 9.6 15.1 9.7 16.7 21.6 15.7 46.0 11.7 16.0 17.6 15.9 12.4 9.3 0.2 8.3 23.8 14.9 15.2 15.1 9.8 13.2 16.3 18.8 23.7 83.9 6.1 24.8 6.5 38.8 17.2 16.3 14.5 19.3 13.2 12.5 10.2 12.8 5.5 13.6 11.5 2.6 9.7 3.7 2.7 7.2 8.3 16.3 0.5 6.6 20.3 18.5 16.5 34.7 11.6 19.3 10.8 11.2 12.2 16.4 19.7 14.9 19.0 14.0 7.3 10.2 7.2 8.0 12.6 9.8 21.4 2.6 1.5 3.5 0.8 3.8 2.9 4.3 3.7 1.6 5.0 6.1 3.9 0.5 3.3 0.3 2.1 4.4 3.4 16.8 25.3 20.0 19.8 17.0 16.4 21.8 23.1 21.1 16.3 23.2 31.6 17.9 6.4 9.2 44.1 35.6 23.6 27.8 8.0 13.1 24.9 15.7 12.7 17.0 14.3 7.8 12.9 27.1 14.8 30.0 8.6 1.9 14.9 29.3 6.6 18.5 20.4 15.6 17.1 70.1 10.7 43.3 23.2 14.8 12.7 23.5 34.8 24.7 16.2 15.3 57.2 72.4 9.1 6.1 18.2 18.8 24.3 26.8 21.7 17.8 39.4 20.6 17.7 58.7 75.4 160.8 11.1 10.9 43.6 21.3 26.2 6.4 11.0 2.8 59.7 46.0 30.5 45.8 10.2 17.8 11.4 24.0 17.8 36.0 13.7 11.3 38.2 CRYBG3 DKFZp667G2110 ENSG00000080200 "Crystallin beta-gamma domain containing 3" Q68DQ2 3 97822011-97944984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 122.6;Bipolar cells: 123.6;Early spermatids: 121.4;Late spermatids: 131.8;Oligodendrocytes: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 8 "dendritic cells: 3.6;granulocytes: 1.5;monocytes: 1.4" "Cell line enhanced" "Detected in many" "SCLC-21H: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075635 Approved "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075635: " "unprognostic (1.88e-1)" "unprognostic (7.62e-3)" "unprognostic (2.54e-1)" "unprognostic (4.56e-2)" "unprognostic (7.60e-2)" "unprognostic (2.70e-2)" "unprognostic (2.45e-2)" "unprognostic (7.10e-2)" "unprognostic (3.41e-3)" "unprognostic (6.59e-2)" "unprognostic (2.80e-2)" "unprognostic (7.86e-2)" "prognostic favorable (7.07e-4)" "unprognostic (1.78e-2)" "unprognostic (1.58e-1)" "unprognostic (1.14e-2)" "unprognostic (6.38e-3)" 10.6 2.8 5.3 5.5 12.6 0.8 7.7 9.2 8.0 8.0 3.4 7.0 3.6 6.6 2.7 8.9 5.6 5.3 6.5 5.3 10.6 4.9 3.2 5.7 3.4 15.5 10.0 3.5 5.4 3.7 1.2 10.7 16.0 5.0 7.6 7.8 6.3 4.1 7.5 12.9 4.5 6.4 11.3 4.0 5.3 14.0 10.0 2.8 26.6 9.9 4.5 7.5 4.6 17.2 16.5 6.1 3.5 4.2 11.1 11.8 6.2 5.8 5.3 4.2 6.3 0.4 5.4 0.1 1.9 10.1 6.2 10.5 7.0 4.9 8.0 20.4 3.8 4.1 2.7 2.1 5.8 6.1 1.0 7.7 4.9 5.3 5.8 6.9 8.2 1.3 0.3 3.0 7.4 0.2 2.2 0.7 3.0 4.5 5.5 0.0 12.3 2.1 6.1 10.9 39.2 3.0 12.2 4.8 3.9 2.2 4.2 6.8 10.9 8.9 6.9 5.2 7.1 5.0 0.1 3.7 9.3 3.5 5.8 1.5 1.4 0.0 0.1 0.9 0.2 0.1 0.2 0.2 1.4 0.2 0.1 0.1 0.0 0.0 1.0 3.6 0.0 0.3 5.3 12.6 9.2 8.0 5.3 10.6 15.5 10.0 16.0 11.3 10.0 17.2 122.6 32.1 19.6 48.0 4.2 5.1 7.0 3.7 23.9 123.6 13.7 9.3 37.6 1.5 16.9 18.4 6.2 4.0 13.8 6.0 1.9 8.8 121.4 32.6 48.9 52.1 12.7 2.5 37.5 13.1 11.3 38.0 18.3 22.7 0.0 68.0 15.0 5.1 6.6 13.5 23.0 8.3 2.0 17.4 3.0 131.8 8.4 18.9 8.8 37.5 22.1 29.4 1.0 10.6 128.3 13.2 8.7 4.5 12.0 7.1 2.5 2.8 21.3 9.6 39.5 29.2 18.2 49.6 9.5 24.5 6.1 2.3 3.0 14.0 5.2 7.0 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 280.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavorable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavorable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 87.1 52.8 81.1 41.2 82.6 51.6 88.3 80.8 95.1 93.6 66.0 73.0 41.4 82.7 52.5 69.0 83.3 48.7 80.9 82.9 73.7 70.2 37.4 92.2 40.3 78.9 78.6 109.5 64.9 74.1 85.1 71.2 79.5 80.3 35.5 47.3 71.6 44.9 60.5 94.8 50.9 45.3 70.2 63.6 58.0 29.5 83.2 33.3 64.4 47.2 37.8 65.7 88.4 93.9 101.5 57.4 121.6 114.7 61.5 88.3 92.1 126.9 168.6 116.7 114.3 63.9 76.7 74.2 53.0 120.7 70.7 77.9 96.1 177.9 79.2 123.0 215.2 23.9 181.2 47.4 123.7 48.3 61.9 90.2 143.8 171.7 220.3 141.0 121.1 60.6 50.9 155.0 110.8 68.4 71.1 60.9 87.2 67.3 69.1 130.8 90.1 123.4 99.0 92.4 181.6 69.3 102.9 109.3 124.7 68.0 59.5 73.0 134.3 94.0 111.3 58.7 102.1 61.2 105.2 104.5 151.0 56.9 176.3 4.8 1.6 3.6 3.0 0.8 3.8 2.1 3.4 3.0 1.8 3.1 1.9 2.5 3.8 5.7 0.5 15.9 1.6 1.2 81.1 82.6 80.8 95.1 82.9 73.7 78.9 78.6 79.5 70.2 83.2 93.9 73.4 38.5 21.7 0.0 32.3 78.6 158.8 89.1 68.9 132.6 53.7 42.4 49.8 34.3 73.9 23.9 60.5 35.2 42.3 28.4 7.9 30.8 46.0 94.3 72.5 76.4 62.8 12.6 0.0 41.8 49.2 60.8 39.8 126.5 3.8 46.6 45.0 21.3 23.1 72.3 0.0 46.0 46.8 17.6 54.1 69.1 85.4 21.8 60.5 0.0 13.3 117.9 28.8 0.0 0.0 57.5 33.1 66.2 83.5 160.5 9.0 6.5 62.8 60.7 72.3 85.7 98.0 8.0 20.0 50.3 104.7 125.5 26.0 34.9 37.6 280.8 CSRP1 "CSRP, CYRP, D1S181E" ENSG00000159176 "Cysteine and glycine rich protein 1" P21291 1 201483530-201509456 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 2743.3;seminal vesicle: 2571.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 341.2;Breast myoepithelial cells: 737.5;Extravillous trophoblasts: 388.5;Smooth muscle cells: 419.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 11000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA045617: AB_2679391" "unprognostic (7.08e-2)" "unprognostic (1.59e-2)" "unprognostic (4.86e-2)" "unprognostic (9.89e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.61e-4)" "unprognostic (2.87e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.24e-2)" "unprognostic (2.58e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.96e-3)" 344.5 127.2 713.6 224.5 871.4 41.0 321.8 742.5 717.3 542.4 467.6 2743.3 180.6 1904.4 308.4 884.1 1025.6 152.7 194.2 647.3 735.1 192.5 114.7 386.0 64.9 840.1 837.4 319.0 114.6 188.0 117.0 118.3 719.0 947.2 432.0 24.2 250.1 2571.3 64.0 219.8 503.6 2009.6 713.5 165.6 748.3 44.2 848.5 48.0 186.4 53.8 65.7 1494.5 469.1 766.6 83.0 195.3 52.0 116.4 83.2 107.7 273.6 605.7 514.3 455.3 360.9 211.1 57.7 78.7 36.1 325.0 96.7 144.7 32.7 120.3 321.2 169.5 29.3 90.7 220.1 30.7 387.4 72.1 10.2 99.3 105.3 373.0 163.1 253.1 508.1 34.9 4.5 71.9 302.1 232.9 46.6 11.8 0.8 99.0 73.2 18.3 304.9 266.8 212.6 129.7 27.1 22.5 238.0 503.8 163.9 25.6 87.0 74.3 610.6 303.7 195.7 206.6 250.6 40.5 82.6 30.6 303.5 137.6 202.6 75.5 49.8 65.6 37.4 49.3 36.9 25.0 35.8 34.9 65.0 18.1 20.5 25.2 5.0 34.3 54.2 5.2 54.1 46.5 713.6 871.4 742.5 717.3 647.3 735.1 840.1 837.4 719.0 713.5 848.5 766.6 151.8 38.5 47.8 86.5 21.8 49.2 341.2 24.6 207.7 3.4 123.7 737.5 24.8 21.5 36.9 47.8 0.0 88.8 23.3 96.6 49.0 165.1 21.5 30.1 73.6 86.9 57.9 19.1 2.4 171.7 388.5 86.7 36.7 38.9 27.9 13.9 91.1 28.3 66.0 0.0 2.1 80.0 14.2 29.1 55.8 44.9 41.0 37.0 126.3 10.3 73.5 137.4 15.5 6.6 114.8 140.5 71.4 292.3 61.5 113.8 97.2 28.4 25.2 3.1 144.7 37.7 419.9 2.4 3.2 75.3 34.9 160.9 31.2 30.4 69.7 103.6 CSRP2 "CRP2, LMO5, SmLIM" ENSG00000175183 "Cysteine and glycine rich protein 2" Q16527 12 76858709-76879023 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.3;Muller glia cells: 625.9;Smooth muscle cells: 268.4;Squamous epithelial cells: 271.2" "Cancer enhanced" "Detected in all" "glioma: 24.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 336.2;BEWO: 177.9;fHDF/TERT166: 184.9;HEK 293: 186.4;NTERA-2: 181.4;WM-115: 188.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 63000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA045617: AB_2679391" "unprognostic (9.06e-2)" "unprognostic (4.32e-2)" "unprognostic (5.18e-3)" "unprognostic (1.58e-1)" "unprognostic (5.40e-1)" "unprognostic (2.79e-3)" "unprognostic (2.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.18e-1)" "unprognostic (3.54e-2)" "unprognostic (2.67e-1)" "prognostic favorable (8.52e-4)" "prognostic unfavorable (4.48e-5)" "unprognostic (3.55e-2)" "unprognostic (4.41e-1)" "unprognostic (3.08e-1)" "unprognostic (3.45e-1)" 68.9 8.2 52.7 32.6 55.5 0.3 52.2 56.9 70.0 77.4 54.4 34.2 17.2 54.3 27.1 98.0 55.8 61.6 37.4 51.6 62.6 88.3 45.2 57.7 27.8 55.5 56.6 30.1 16.6 11.6 28.7 84.0 57.7 48.5 16.3 64.9 29.9 15.9 15.3 24.1 39.0 37.2 55.5 19.4 45.8 23.7 61.4 26.9 50.0 34.4 37.5 47.4 62.6 61.4 26.0 23.0 336.2 67.7 15.0 3.3 177.9 43.7 52.5 39.3 108.2 15.3 1.1 0.3 17.5 184.9 30.9 31.4 75.3 44.5 63.0 3.2 186.4 0.3 46.4 14.9 3.7 0.0 0.7 18.0 29.5 31.8 5.6 67.8 8.1 12.9 1.2 1.0 68.8 8.3 3.8 0.3 181.4 1.6 39.1 39.5 90.9 0.3 130.3 61.7 17.4 111.8 74.3 2.7 17.9 92.5 0.1 0.8 1.9 34.3 44.4 8.5 32.6 2.2 1.9 3.7 10.5 0.6 188.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 52.7 55.5 56.9 70.0 51.6 62.6 55.5 56.6 57.7 55.5 61.4 61.4 93.8 0.0 1.7 6.2 1.8 78.5 105.5 24.3 133.7 16.7 12.7 57.0 14.4 20.0 8.5 14.7 10.4 275.3 2.7 0.8 215.2 28.5 35.3 107.1 16.1 119.1 0.0 0.0 4.7 4.4 156.7 116.6 7.7 82.4 0.0 61.7 13.2 25.7 28.8 0.0 2.1 2.5 2.0 1.0 43.7 21.0 3.7 5.3 49.8 13.1 76.1 625.9 0.0 2.5 0.6 5.5 1.4 9.1 8.1 72.7 0.4 140.8 2.7 19.4 210.4 138.0 268.4 81.2 44.8 271.2 61.9 117.9 5.9 25.1 3.8 55.0 DACT2 "bA503C24.7, C6orf116, DAPPER2" ENSG00000164488 "Dishevelled binding antagonist of beta catenin 2" Q5SW24 6 168292830-168319777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.4;placenta: 12.9" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 58.2;Syncytiotrophoblasts: 216.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 14.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.2;CACO-2: 2.7;hTCEpi: 1.8;NTERA-2: 2.2;OE19: 11.2;SCLC-21H: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basal ganglia: 16.9;cerebral cortex: 21.4;hippocampal formation: 16.8" HPA030251 Enhanced Supported NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA030251: AB_10611108" "unprognostic (5.22e-6)" "unprognostic (3.13e-2)" "unprognostic (1.04e-2)" "prognostic favorable (1.07e-5)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (4.04e-1)" "unprognostic (1.31e-1)" "unprognostic (7.05e-3)" "unprognostic (2.48e-1)" "prognostic favorable (5.76e-5)" "unprognostic (1.51e-2)" "unprognostic (1.66e-2)" "unprognostic (2.03e-4)" "unprognostic (4.23e-2)" 2.3 3.3 3.7 0.4 19.4 0.0 0.6 2.9 6.2 1.7 1.4 1.0 0.8 2.7 0.1 1.5 1.7 0.4 5.2 2.7 2.7 3.6 5.8 1.6 0.4 4.1 3.5 0.1 2.9 0.0 0.6 12.9 4.6 7.3 0.3 5.8 6.5 0.4 0.2 5.7 0.6 0.2 2.8 0.0 0.7 1.0 4.1 1.9 0.3 0.0 0.6 1.1 1.2 3.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 11.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 19.4 2.9 6.2 2.7 2.7 4.1 3.5 4.6 2.8 4.1 3.0 0.0 0.0 2.0 0.0 0.0 3.1 1.9 0.8 0.0 10.7 0.1 3.0 0.6 1.5 1.3 1.8 0.0 58.2 0.0 0.1 0.0 1.3 0.0 11.8 0.5 0.7 5.3 0.0 0.1 0.2 6.1 3.4 0.0 11.0 0.0 3.3 0.0 0.3 5.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.1 3.6 6.5 0.0 26.3 0.0 0.0 0.1 0.3 1.2 0.0 0.0 1.1 0.0 5.7 0.0 0.9 0.0 0.5 0.1 0.0 0.3 0.0 1.4 216.3 0.2 0.0 1.9 0.1 DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.9;Oligodendrocytes: 27.2;Smooth muscle cells: 22.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 10.5;SH-SY5Y: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" 9.1 3.3 42.1 5.9 42.0 1.4 5.4 41.1 54.4 34.7 3.6 53.9 3.9 48.2 14.3 7.4 37.4 7.2 27.5 48.6 33.4 5.9 2.6 14.0 1.1 45.4 40.1 17.0 1.1 1.9 4.1 1.7 39.9 19.7 6.7 5.8 1.7 24.6 2.2 4.1 13.0 31.6 34.7 6.8 18.0 18.7 46.3 0.5 4.8 2.9 0.9 39.0 15.9 58.0 0.2 0.2 5.6 5.3 1.9 1.5 0.5 3.1 5.2 1.0 1.5 0.2 0.3 0.5 2.0 10.5 1.0 0.3 3.6 0.1 1.0 0.3 1.9 1.2 0.8 0.2 2.7 0.1 2.1 4.9 0.1 1.3 0.1 0.6 0.4 0.7 1.8 1.8 0.9 0.4 0.2 1.4 2.2 0.0 0.8 4.6 1.3 0.3 0.2 0.3 2.1 24.6 0.4 0.2 0.4 5.7 0.4 0.5 0.4 2.6 3.2 2.6 0.5 1.6 0.5 0.8 0.5 0.8 1.9 2.6 0.3 0.3 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.5 0.2 0.2 1.6 0.7 0.2 0.3 0.2 0.1 42.1 42.0 41.1 54.4 48.6 33.4 45.4 40.1 39.9 34.7 46.3 58.0 1.9 6.4 5.5 13.7 0.2 2.3 1.5 0.0 0.0 16.5 1.0 2.4 17.8 1.5 0.7 0.0 2.1 5.4 0.5 0.3 0.0 0.0 23.9 0.4 9.3 3.1 1.8 0.0 9.2 0.0 2.6 7.4 0.0 0.8 6.3 0.5 1.8 0.2 1.1 1.7 16.7 0.2 2.0 1.6 9.2 8.6 7.8 1.4 3.6 7.5 1.2 9.2 2.1 15.1 27.2 0.1 1.2 14.7 0.1 1.0 0.2 0.3 0.2 6.3 6.6 2.3 22.9 2.3 2.5 0.4 3.3 9.9 1.0 4.3 0.2 1.0 DCHS2 "CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ" ENSG00000197410 "Dachsous cadherin-related 2" Q6V1P9 4 154231742-154491799 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7" "Cell type enhanced" "Detected in some" "Astrocytes: 63.0;Early spermatids: 20.7;Excitatory neurons: 30.3;Horizontal cells: 25.2;Inhibitory neurons: 13.2;Late spermatids: 19.4;Microglial cells: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "U-2 OS: 4.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA064159 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA064159: AB_2685201" "unprognostic (1.38e-2)" "unprognostic (1.51e-1)" "unprognostic (5.74e-3)" "unprognostic (5.93e-2)" "unprognostic (7.43e-3)" "unprognostic (1.29e-1)" "unprognostic (2.27e-4)" "unprognostic (1.18e-1)" "unprognostic (4.00e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-3)" "unprognostic (1.62e-1)" "unprognostic (1.06e-3)" "unprognostic (3.13e-1)" "unprognostic (2.62e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-3)" 0.0 0.1 0.6 0.0 0.8 0.0 0.1 0.3 0.5 0.9 0.0 1.7 0.0 1.4 0.0 0.0 0.9 0.1 0.0 0.4 0.8 0.1 0.0 0.1 0.0 0.5 1.3 0.7 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.2 0.3 0.1 0.7 0.0 1.2 1.1 1.1 0.0 0.0 0.0 0.0 0.6 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.3 0.5 0.4 0.8 0.5 1.3 0.3 0.7 1.1 1.4 0.0 0.0 0.0 63.0 0.0 0.4 0.2 0.8 0.0 0.4 0.8 0.6 1.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.7 0.1 0.5 0.3 6.7 0.0 30.3 0.0 0.0 1.8 3.6 0.0 0.0 1.2 0.0 0.0 0.1 25.2 13.2 0.1 0.0 0.0 0.7 19.4 0.6 0.0 0.0 13.1 0.0 0.2 0.0 6.6 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.9 0.2 0.0 0.3 0.5 1.7 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DENND5A "FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1" ENSG00000184014 "DENN domain containing 5A" Q6IQ26 11 9138825-9265959 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 287.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052923, HPA055009" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" "HPA052923: AB_2681989, HPA055009: AB_2682669" "unprognostic (5.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.17e-1)" "unprognostic (1.28e-2)" "unprognostic (4.03e-1)" "unprognostic (3.48e-1)" "prognostic unfavorable (5.05e-6)" "unprognostic (1.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "unprognostic (5.15e-2)" "unprognostic (3.10e-1)" "prognostic unfavorable (1.14e-6)" "unprognostic (9.86e-3)" "unprognostic (1.03e-1)" "unprognostic (4.32e-1)" "unprognostic (1.40e-2)" 45.8 23.5 72.4 23.2 90.5 21.7 36.3 85.0 80.7 36.1 45.5 44.2 5.8 38.5 14.1 17.4 37.5 23.3 58.0 65.1 85.4 25.5 15.7 46.1 16.8 81.5 86.6 30.2 23.2 18.5 20.5 28.8 77.0 24.5 12.9 34.7 19.5 40.0 26.7 17.3 20.2 47.5 74.9 31.4 23.7 15.8 87.3 28.0 22.0 33.7 15.9 40.4 25.1 81.3 18.8 23.3 63.7 56.1 113.0 92.0 61.7 69.2 99.8 85.7 104.5 16.4 13.6 0.0 30.5 129.0 82.4 12.7 64.3 22.5 111.4 73.0 30.9 6.2 32.2 34.5 61.0 34.4 13.9 76.8 11.5 51.1 74.6 59.7 83.8 21.9 33.6 0.3 101.9 11.0 19.4 15.1 19.7 3.2 28.6 34.2 46.1 0.3 41.6 13.4 15.9 32.1 65.8 29.7 27.2 70.4 15.7 24.6 59.2 63.0 41.0 78.7 47.3 1.4 0.4 18.7 63.4 14.1 51.9 4.4 5.0 5.7 0.1 6.3 0.6 1.8 1.3 1.3 4.6 0.2 3.8 1.9 10.8 1.0 9.2 1.1 0.0 1.9 72.4 90.5 85.0 80.7 65.1 85.4 81.5 86.6 77.0 74.9 87.3 81.3 34.1 19.2 14.5 43.8 7.4 21.7 19.3 10.3 10.2 9.7 15.3 13.8 33.2 14.3 8.0 14.7 60.5 15.9 6.4 0.3 0.0 7.3 1.1 26.3 31.8 31.3 6.6 7.8 47.7 6.7 20.1 27.1 3.1 57.8 2.5 11.6 21.4 10.9 21.8 13.5 74.2 2.2 4.1 36.3 63.4 2.0 21.5 48.9 19.6 68.4 41.1 11.6 3.1 136.2 287.1 8.4 1.4 20.7 0.9 32.5 0.1 10.3 4.8 10.5 26.3 34.4 31.6 7.9 12.3 6.3 8.2 11.2 6.3 16.0 0.8 15.0 DIXDC1 "Dixin, KIAA1735" ENSG00000150764 "DIX domain containing 1" Q155Q3 11 111927144-112022653 "Predicted intracellular proteins" "Wnt signaling pathway" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 104.3;Horizontal cells: 121.1;Oligodendrocytes: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 5.2" "Lineage enriched" "Detected in single" 11 "granulocytes: 5.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 42.7;TIME: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039424, HPA039658, HPA061366" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA039424: AB_2676500, HPA039658: AB_2676611, HPA061366: " "unprognostic (1.93e-1)" "unprognostic (2.90e-2)" "unprognostic (8.93e-3)" "unprognostic (2.84e-1)" "unprognostic (2.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-1)" "unprognostic (1.41e-1)" "unprognostic (7.23e-2)" "unprognostic (1.59e-1)" "unprognostic (7.85e-2)" "unprognostic (5.11e-2)" "prognostic favorable (6.89e-5)" "unprognostic (4.10e-2)" "unprognostic (2.11e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (4.19e-5)" 17.8 17.7 16.4 8.6 23.2 0.7 15.0 36.8 22.6 18.7 22.8 29.5 5.6 24.8 18.6 12.7 20.4 12.6 23.3 17.0 16.9 11.4 7.0 9.4 2.6 20.1 21.8 15.8 3.8 17.1 7.1 10.8 19.1 23.4 10.0 22.0 7.8 35.8 13.7 5.4 9.1 25.6 18.0 2.9 14.9 19.1 19.7 2.6 10.7 12.3 2.5 25.3 12.0 34.4 0.8 3.7 9.9 18.5 29.9 17.5 2.1 7.7 5.3 2.9 5.2 0.6 2.0 1.6 2.0 21.5 3.4 0.9 4.4 2.4 2.9 6.4 3.7 0.8 5.8 10.3 4.6 5.3 0.7 14.2 19.3 6.3 42.7 21.5 30.6 4.0 5.2 0.6 11.9 0.9 3.3 4.6 5.9 0.8 6.6 1.6 2.9 6.1 12.1 0.3 8.0 16.7 5.7 4.6 2.5 4.3 6.8 2.0 50.4 13.1 5.6 2.4 12.9 1.2 5.5 0.8 7.2 13.5 4.7 0.0 0.1 5.2 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.1 16.4 23.2 36.8 22.6 17.0 16.9 20.1 21.8 19.1 18.0 19.7 34.4 12.8 16.0 10.3 40.1 0.4 6.4 16.3 4.1 11.4 22.3 23.7 28.8 35.6 7.2 10.1 18.4 104.3 1.4 0.9 2.6 15.6 6.4 23.1 32.1 48.6 28.1 2.4 2.1 47.7 7.7 5.1 32.8 11.7 11.3 1.3 6.3 62.8 19.3 1.7 121.1 83.8 13.9 6.1 3.4 5.3 17.5 39.7 1.5 12.4 20.6 1.0 30.2 0.0 34.7 140.4 7.0 6.2 36.9 2.0 10.8 2.7 15.4 35.5 69.2 13.1 25.3 31.8 62.3 16.4 3.3 4.1 1.4 2.0 3.5 4.5 3.1 DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Alveolar cells type 2: 225.9;Excitatory neurons: 208.8;Microglial cells: 317.6;Oligodendrocyte precursor cells: 244.3;Oligodendrocytes: 707.2;Sertoli cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 83.2;U-2197: 98.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017753 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" Nucleoplasm "HPA017753: AB_10600805" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.11e-4)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (8.46e-3)" "unprognostic (6.49e-2)" "unprognostic (2.02e-2)" "unprognostic (3.56e-3)" "unprognostic (2.79e-2)" "unprognostic (7.33e-2)" "unprognostic (1.67e-1)" 52.5 10.6 17.8 8.8 28.7 2.6 29.6 21.8 18.2 13.5 4.8 19.6 5.6 16.1 5.3 6.3 14.7 19.1 21.5 22.9 21.3 13.7 20.4 42.9 3.8 27.8 23.5 9.5 9.0 6.1 5.3 24.2 29.0 6.7 6.2 1.5 5.6 4.2 7.2 7.1 11.5 19.1 18.8 16.4 13.6 4.0 22.5 2.1 15.7 10.3 1.8 15.4 11.1 38.0 0.1 0.7 6.6 0.0 69.4 35.5 20.3 39.3 33.7 40.7 48.6 11.5 6.6 0.0 9.7 51.4 39.4 6.6 4.3 7.4 83.2 0.0 7.2 39.5 0.1 21.7 31.8 0.0 13.7 36.6 0.6 62.6 46.7 43.3 46.7 0.1 2.7 0.0 33.6 0.8 0.0 0.0 0.7 1.4 4.7 0.0 0.0 0.0 19.7 24.4 0.0 2.9 0.0 1.1 31.8 27.4 0.0 0.0 61.7 45.5 18.8 98.7 15.3 0.1 0.0 0.0 31.6 0.3 63.4 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.8 28.7 21.8 18.2 22.9 21.3 27.8 23.5 29.0 18.8 22.5 38.0 171.7 250.0 225.9 177.3 2.3 14.8 2.5 4.8 5.2 0.9 9.3 8.3 37.8 24.3 19.7 3.7 0.0 7.8 0.6 0.4 1.9 3.1 8.4 15.3 36.1 138.4 1.2 25.2 208.8 4.4 2.3 74.2 4.6 27.3 68.2 0.1 193.1 25.7 3.6 13.5 151.8 1.2 0.0 18.6 17.0 4.3 72.4 6.2 24.9 317.6 0.2 1.0 0.0 244.3 707.2 3.0 1.3 36.1 1.9 1.4 6.1 1.9 3.0 1.9 223.5 50.0 138.0 6.2 11.4 1.8 9.2 2.7 3.6 31.1 2.9 1.7 DOCK9 "KIAA1058, ZIZ1" ENSG00000088387 "Dedicator of cytokinesis 9" Q9BZ29 13 98793429-99086625 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 216.7" "Cell type enhanced" "Detected in many" "Adipocytes: 158.7;Excitatory neurons: 150.6;Inhibitory neurons: 202.2;Microglial cells: 148.0;Oligodendrocyte precursor cells: 238.8;Oligodendrocytes: 402.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 2.0;MAIT T-cell: 4.8;memory CD4 T-cell: 5.2;memory CD8 T-cell: 2.1;naive CD4 T-cell: 6.0;naive CD8 T-cell: 4.0;NK-cell: 7.3;T-reg: 2.4" "Group enriched" "Detected in many" 11 "NK-cells: 7.3;T-cells: 6.0" "Cell line enhanced" "Detected in many" "BEWO: 200.8;hTERT-HME1: 435.4;HUVEC TERT2: 180.9;TIME: 179.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034061, CAB034065, HPA043940" Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB034061: AB_2277513, CAB034065: AB_2094798, HPA043940: AB_2678741" "unprognostic (5.31e-2)" "unprognostic (3.20e-2)" "unprognostic (8.76e-2)" "unprognostic (4.24e-2)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.62e-2)" "unprognostic (2.96e-1)" "unprognostic (2.47e-1)" "unprognostic (1.16e-1)" "unprognostic (6.38e-3)" "unprognostic (2.79e-1)" "unprognostic (7.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.36e-2)" "unprognostic (3.31e-2)" 83.2 22.4 82.6 21.4 137.2 6.0 71.1 96.6 91.0 42.9 30.8 44.4 15.7 31.3 35.5 93.1 30.3 36.6 58.9 72.8 93.8 21.9 15.8 93.0 33.8 116.6 112.1 27.4 19.9 41.8 21.1 98.2 123.4 23.0 20.8 39.5 51.2 21.7 25.9 76.9 35.2 36.9 86.6 16.8 24.7 16.2 110.4 47.8 62.6 64.3 40.4 29.0 49.6 216.7 61.6 19.4 10.6 14.2 10.6 8.3 200.8 17.2 14.2 12.1 10.7 127.4 47.7 51.3 39.8 16.6 21.8 59.5 27.4 54.3 21.8 52.2 15.2 0.0 37.6 2.1 14.0 0.1 2.9 9.0 37.2 12.4 435.4 27.9 180.9 33.0 10.6 11.6 52.1 20.2 35.5 0.3 4.9 84.6 14.2 2.1 39.3 2.7 38.3 50.8 22.4 24.3 26.4 63.4 15.7 85.9 16.9 0.4 179.7 9.7 11.4 6.5 28.5 17.6 14.8 8.6 15.6 0.0 16.0 0.0 0.0 0.0 2.0 0.0 4.8 0.6 5.2 2.1 0.0 0.2 6.0 4.0 0.1 7.3 0.0 0.0 2.4 1.5 82.6 137.2 96.6 91.0 72.8 93.8 116.6 112.1 123.4 86.6 110.4 216.7 158.7 16.0 39.5 37.5 3.4 15.3 7.1 14.7 10.2 37.9 15.4 6.5 9.4 11.5 12.5 9.2 50.1 35.6 7.0 11.9 1.9 5.4 1.7 10.5 5.3 90.2 6.7 3.6 150.6 6.6 8.3 17.2 2.6 21.4 2.5 18.0 47.8 8.4 5.0 25.2 202.2 6.0 10.2 1.9 7.4 3.3 7.8 1.7 1.8 148.0 0.4 12.9 4.1 238.8 402.2 14.7 5.6 14.7 2.8 10.1 10.6 3.8 7.1 23.9 0.0 122.6 12.4 7.2 5.4 25.6 32.0 17.2 11.0 2.4 5.9 10.5 DPP6 "DPL1, DPPX" ENSG00000130226 "Dipeptidyl peptidase like 6" P42658 7 153887097-154894285 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.0;endometrium 1: 58.2" "Group enriched" "Detected in many" 4 "Excitatory neurons: 673.4;Inhibitory neurons: 1195.9;Oligodendrocyte precursor cells: 1947.8" "Cancer enriched" "Detected in some" 11 "glioma: 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "NTERA-2: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050509 Enhanced Supported NA NA "Cluster 42: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA050509: AB_2681150" "unprognostic (1.29e-1)" "unprognostic (3.55e-2)" "unprognostic (5.68e-2)" "unprognostic (5.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.28e-1)" "unprognostic (2.73e-1)" "unprognostic (5.83e-4)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.04e-3)" "unprognostic (2.94e-3)" "unprognostic (1.85e-4)" "unprognostic (1.05e-1)" "unprognostic (4.61e-3)" "unprognostic (6.11e-2)" 0.6 8.2 16.5 0.2 24.5 0.1 0.5 32.0 34.5 5.8 0.0 19.8 0.5 58.2 2.5 0.3 5.2 0.1 0.2 42.7 21.6 5.3 0.0 1.4 0.1 54.0 24.5 0.7 3.9 0.0 10.8 0.2 53.1 0.3 1.6 11.1 0.1 8.9 6.0 3.6 3.4 19.9 8.6 4.7 7.8 7.3 32.2 1.9 17.1 0.9 0.0 0.3 1.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 11.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.0 16.5 24.5 32.0 34.5 42.7 21.6 54.0 24.5 53.1 8.6 32.2 14.8 0.1 0.0 0.0 147.9 0.0 3.3 0.4 0.0 0.0 27.0 0.4 1.3 7.4 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 13.4 0.9 21.6 0.4 10.3 0.0 673.4 4.0 0.0 2.1 0.0 0.5 0.0 0.0 0.0 0.0 0.2 32.0 1195.9 0.4 0.0 0.0 0.0 18.4 1.2 0.2 16.0 22.5 0.0 17.1 0.0 1947.8 290.8 0.3 0.0 3.8 0.0 0.1 0.1 0.4 0.8 6.1 0.0 0.7 0.9 1.2 4.0 0.0 1.6 0.0 0.2 0.0 0.0 0.2 DPYSL3 "CRMP4, DRP-3, ULIP" ENSG00000113657 "Dihydropyrimidinase like 3" Q14195 5 147390808-147510068 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 101.5;Cone photoreceptor cells: 331.5;Granulosa cells: 261.9;Peritubular cells: 205.7;Rod photoreceptor cells: 125.0" "Cancer enhanced" "Detected in all" "glioma: 109.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 685.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010948 Approved Approved Cytosol NA NA 740000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA010948: AB_1847245" "unprognostic (3.92e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-3)" "unprognostic (1.39e-1)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (5.99e-2)" "unprognostic (6.92e-2)" "unprognostic (4.72e-2)" "unprognostic (2.08e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.87e-9)" "unprognostic (1.14e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.23e-4)" 58.4 18.6 63.4 54.4 68.6 0.8 37.5 60.3 55.8 66.1 30.4 142.1 18.4 119.9 73.9 69.0 63.4 65.1 59.2 57.0 116.0 7.7 4.4 45.2 18.1 123.7 94.2 88.0 5.5 2.7 12.7 19.8 81.8 104.6 37.6 163.8 24.5 162.0 68.7 23.8 43.3 217.6 115.2 26.4 40.9 19.9 95.2 7.1 22.4 36.0 27.0 118.0 50.6 105.1 0.5 36.1 63.9 0.1 2.3 63.3 1.6 34.1 163.0 71.4 94.4 114.5 3.1 0.0 9.6 100.1 37.4 3.7 13.1 1.4 79.1 16.3 29.2 0.1 30.0 0.2 63.1 0.3 0.2 12.2 0.6 153.8 60.3 178.7 206.9 0.0 0.0 1.3 41.1 0.3 0.2 0.6 135.9 0.2 53.7 0.2 135.1 0.5 63.0 14.2 47.1 685.4 0.3 0.3 10.8 87.9 0.5 1.0 91.1 51.6 38.5 127.0 127.3 113.9 21.7 0.2 47.5 1.4 27.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.4 68.6 60.3 55.8 57.0 116.0 123.7 94.2 81.8 115.2 95.2 105.1 59.9 0.0 2.8 101.5 0.0 9.4 3.4 1.5 2.2 14.2 8.1 6.6 7.8 1.5 4.0 0.0 331.5 0.1 0.0 0.2 0.0 9.1 16.8 0.3 4.6 62.6 6.6 0.0 11.3 8.4 0.3 79.8 3.1 1.2 1.3 261.9 57.8 0.4 1.6 5.0 12.9 0.2 24.4 1.2 11.9 19.2 42.9 3.1 19.6 5.6 0.0 28.3 0.0 83.9 0.7 13.7 0.0 205.7 0.3 10.1 0.0 0.1 2.8 125.0 0.0 23.6 40.9 1.8 3.2 3.7 8.2 0.4 1.5 49.6 0.3 4.5 DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2368.6;Basal prostatic cells: 1651.4;Basal squamous epithelial cells: 3008.4;Cone photoreceptor cells: 1401.1;Oligodendrocytes: 1410.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 488.1;hTERT-HME1: 371.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Microtubules" Cytosol "HPA030200: AB_10601901" "unprognostic (4.87e-3)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (3.60e-2)" "unprognostic (5.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (7.62e-2)" 60.9 86.2 206.5 16.2 275.8 3.3 117.3 240.6 221.9 158.8 143.3 173.2 25.4 167.1 38.2 66.1 103.9 32.6 166.0 194.6 230.7 52.2 80.8 108.0 11.3 258.1 250.4 78.2 39.8 36.7 78.8 28.7 263.4 84.5 32.4 87.4 100.3 48.7 143.1 166.2 64.2 106.0 209.1 36.7 68.9 28.4 243.3 31.4 29.8 104.1 15.2 90.4 113.2 325.4 62.4 26.6 41.2 20.8 79.5 103.5 24.6 82.2 89.7 37.8 42.1 17.1 15.5 10.4 32.2 220.7 35.6 46.7 34.4 161.2 73.0 52.3 45.2 17.8 49.5 31.4 65.9 15.0 0.4 58.3 488.1 92.5 371.6 69.1 73.3 9.5 12.6 38.2 113.9 20.2 5.1 6.8 27.7 35.6 21.9 0.1 28.8 16.5 118.8 83.0 47.2 37.8 32.7 11.7 64.1 67.7 18.6 27.2 176.5 77.3 55.9 37.0 68.9 39.6 28.6 5.0 55.8 8.8 40.3 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 0.3 1.3 0.0 0.1 206.5 275.8 240.6 221.9 194.6 230.7 258.1 250.4 263.4 209.1 243.3 325.4 193.2 336.5 11.8 1048.7 5.6 2368.6 1651.4 250.1 3008.4 673.1 81.0 301.5 862.8 77.2 161.7 55.2 1401.1 61.5 7.8 357.8 7.9 204.3 53.6 133.8 218.4 122.7 44.9 12.4 550.4 66.3 11.6 212.5 71.9 166.8 17.1 478.7 60.7 80.3 21.8 307.9 591.7 100.3 118.0 74.2 124.6 15.5 133.3 56.6 215.3 215.5 46.6 200.8 2.1 630.3 1410.3 194.1 283.0 152.4 27.2 229.8 124.2 10.3 52.0 122.6 65.7 381.8 196.6 20.0 13.7 298.2 857.2 26.5 19.7 30.5 48.1 142.8 EBF4 "COE4, KIAA1442, O/E-4, RP5-860F19.3" ENSG00000088881 "EBF family member 4" Q9BQW3 20 2692874-2760108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.9;Cholangiocytes: 21.5;Endometrial stromal cells: 18.6;Oligodendrocyte precursor cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 7.9;HEK 293: 8.4;SH-SY5Y: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (9.57e-2)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (7.79e-3)" "unprognostic (3.82e-1)" "prognostic favorable (2.47e-5)" "unprognostic (2.68e-2)" "unprognostic (5.58e-3)" "unprognostic (1.87e-3)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.87e-3)" 2.6 3.5 12.1 2.7 13.5 0.3 2.7 9.1 15.0 5.0 3.0 3.2 2.8 19.0 2.2 4.1 6.7 5.7 2.9 12.9 11.1 2.6 1.1 3.6 2.3 13.4 11.4 13.7 3.8 14.4 2.9 5.7 9.9 12.4 1.9 3.3 5.6 11.1 1.1 2.8 3.8 12.1 10.6 2.2 3.9 1.2 13.1 0.6 18.0 1.5 1.8 3.0 2.0 17.4 0.0 0.7 4.4 4.4 0.1 1.1 0.9 1.2 3.2 2.2 1.1 0.6 0.4 0.0 2.5 0.5 7.9 0.2 1.5 0.2 1.3 6.2 8.4 0.0 0.0 0.2 2.8 0.0 0.0 0.1 1.0 1.0 0.0 0.8 0.3 1.9 0.0 0.0 0.0 0.4 0.1 6.9 0.6 0.0 0.2 6.4 1.2 0.5 0.0 2.7 3.3 21.2 1.2 0.1 1.9 4.2 2.4 0.3 1.7 0.3 1.0 0.2 3.8 1.4 0.2 1.5 0.0 0.9 3.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.1 13.5 9.1 15.0 12.9 11.1 13.4 11.4 9.9 10.6 13.1 17.4 4.1 0.0 1.1 18.9 0.3 3.4 15.6 3.0 6.8 7.7 18.1 11.0 2.2 21.5 5.5 1.8 0.0 0.2 5.1 0.2 0.0 2.0 0.4 1.2 18.6 3.2 0.0 0.0 3.1 0.4 0.1 5.1 1.1 1.1 0.0 1.9 6.4 5.7 0.3 5.0 12.2 0.2 4.1 0.8 1.4 0.8 3.4 0.3 1.8 10.3 0.0 5.5 2.1 52.3 17.9 0.3 1.7 7.2 0.4 11.3 0.0 0.2 4.9 2.3 6.6 3.3 5.1 0.6 1.4 0.6 1.0 0.3 0.7 0.1 0.4 9.3 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EFHD1 FLJ13612 ENSG00000115468 "EF-hand domain family member D1" Q9BUP0 2 232606057-232682780 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 414.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 241.8;Breast myoepithelial cells: 129.0;Distal tubular cells: 393.2;Oligodendrocytes: 173.4;Sertoli cells: 197.2;Smooth muscle cells: 130.9;Syncytiotrophoblasts: 263.9" "Cancer enriched" "Detected in all" 5 "breast cancer: 100.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 125.8;RPTEC TERT1: 68.6;SK-BR-3: 301.8;T-47d: 236.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049331, HPA056959" Enhanced Supported "Nucleoli fibrillar center,Golgi apparatus" No NA 14000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "Nucleoli fibrillar center" "HPA049331: AB_2680716, HPA056959: AB_2683288" "unprognostic (9.51e-3)" "unprognostic (2.21e-2)" "unprognostic (4.78e-3)" "unprognostic (3.25e-1)" "unprognostic (3.40e-1)" "unprognostic (9.70e-2)" "unprognostic (9.02e-2)" "unprognostic (1.13e-1)" "unprognostic (3.29e-3)" "unprognostic (1.21e-1)" "unprognostic (5.57e-2)" "unprognostic (9.99e-2)" "prognostic favorable (2.93e-7)" "unprognostic (2.00e-2)" "unprognostic (1.84e-1)" "unprognostic (2.51e-2)" "unprognostic (2.29e-3)" 86.3 7.0 199.7 3.7 303.2 0.8 180.7 244.9 261.3 86.9 129.9 16.9 4.4 72.4 33.7 9.6 73.7 12.0 46.0 196.6 217.4 186.2 54.6 15.3 3.9 253.6 258.7 76.5 86.5 10.5 16.5 77.9 261.8 25.6 5.7 9.5 22.2 27.7 35.5 30.9 16.2 20.6 201.4 52.5 17.6 20.1 237.8 3.0 32.7 42.7 2.4 22.0 44.5 414.6 0.0 3.4 5.7 1.4 2.2 0.1 125.8 26.8 2.1 2.3 1.9 0.9 0.6 0.1 2.0 11.6 2.9 0.2 19.0 0.0 0.3 0.5 9.2 0.0 2.4 1.9 0.0 0.1 0.3 1.0 0.4 0.2 0.0 0.4 0.0 5.5 3.9 0.5 0.5 2.3 0.6 0.2 8.4 0.0 0.2 0.6 7.2 0.4 68.6 0.7 0.3 3.2 9.1 301.8 18.3 42.3 236.9 2.6 0.0 0.0 1.8 0.4 0.8 0.2 0.1 0.1 0.3 0.1 13.4 1.0 0.2 0.1 0.2 0.1 0.4 0.3 0.3 0.4 0.1 0.1 0.6 0.6 2.2 0.1 0.1 0.2 0.1 0.1 199.7 303.2 244.9 261.3 196.6 217.4 253.6 258.7 261.8 201.4 237.8 414.6 15.6 0.0 0.0 37.5 1.5 3.6 2.8 1.3 1.2 0.5 241.8 129.0 7.4 1.5 4.6 35.0 0.0 112.0 3.0 0.3 393.2 0.0 9.0 1.1 37.8 16.8 0.0 2.7 2.6 0.0 19.7 41.1 0.0 1.7 0.0 3.2 6.4 89.4 8.7 0.0 5.3 0.1 59.0 1.3 3.0 7.0 44.4 2.1 8.8 18.7 0.0 48.0 0.0 1.5 173.4 0.0 0.0 57.2 0.1 4.6 0.0 116.5 1.9 1.4 197.2 8.7 130.9 17.3 13.6 0.4 3.1 263.9 2.5 1.5 0.3 2.0 ENAH "FLJ10773, MENA, NDPP1" ENSG00000154380 "ENAH actin regulator" Q8N8S7 1 225486835-225653142 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028448, HPA028696" Enhanced Enhanced "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 15000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028448: AB_10600766, HPA028696: AB_10611249" "unprognostic (2.56e-2)" "unprognostic (8.03e-2)" "unprognostic (1.09e-1)" "unprognostic (4.35e-2)" "unprognostic (5.61e-3)" "unprognostic (2.85e-1)" "unprognostic (1.21e-3)" "unprognostic (2.30e-1)" "unprognostic (2.23e-1)" "unprognostic (9.22e-2)" "unprognostic (4.71e-3)" "unprognostic (2.14e-1)" "unprognostic (2.24e-3)" "unprognostic (8.84e-2)" "unprognostic (5.83e-2)" "unprognostic (7.92e-2)" "unprognostic (2.93e-2)" 26.3 20.2 30.3 16.5 25.9 0.5 13.4 21.1 20.3 13.5 2.0 30.9 12.5 23.6 13.7 16.2 15.0 23.6 25.2 27.2 35.7 7.0 7.5 17.3 4.7 35.5 34.2 22.6 22.3 17.9 6.5 18.2 28.1 21.4 10.1 8.1 20.9 30.6 20.4 10.6 10.8 57.6 22.4 24.8 23.3 25.0 40.9 9.0 7.3 11.5 4.6 30.1 13.8 28.7 91.6 71.9 87.1 79.0 33.3 43.7 111.9 99.1 47.3 58.4 43.9 46.4 33.0 38.7 256.8 153.9 52.5 79.0 102.7 37.4 55.2 0.6 63.4 40.3 62.4 63.1 99.4 4.8 1.5 67.9 44.2 75.9 96.2 47.8 47.0 10.7 2.7 1.9 58.6 17.7 18.5 4.7 146.8 23.9 64.3 27.6 122.9 1.1 26.9 69.5 85.3 68.9 194.6 73.3 63.3 66.1 87.5 5.9 92.2 150.4 109.8 126.8 198.6 4.2 11.4 25.7 82.7 5.0 78.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 30.3 25.9 21.1 20.3 27.2 35.7 35.5 34.2 28.1 22.4 40.9 28.7 117.0 12.8 37.3 81.9 3.8 129.0 172.5 64.4 26.2 11.2 96.2 57.9 119.3 54.3 56.5 22.0 62.6 65.0 1.7 14.8 3.9 84.7 74.8 127.2 60.5 79.3 41.4 0.0 86.3 100.5 18.5 71.6 63.2 75.0 5.1 194.2 23.9 12.9 11.2 16.8 155.0 27.3 26.4 1.6 29.7 24.3 58.1 4.3 83.6 41.2 3.8 32.6 3.1 160.4 151.3 61.5 16.5 168.9 1.6 133.1 3.5 19.6 137.8 19.0 92.1 69.4 166.1 13.4 37.2 25.6 134.1 60.5 4.8 220.7 31.3 100.3 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;fallopian tube: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 0.3 0.4 10.0 0.0 13.3 0.0 5.6 10.5 11.5 2.9 0.0 0.1 0.0 0.2 0.0 0.1 11.2 0.0 3.0 9.9 12.7 5.1 0.0 0.8 0.0 4.9 16.9 0.1 0.6 3.1 2.4 0.1 7.6 0.3 0.0 2.0 4.7 1.2 1.5 0.3 0.0 0.0 4.3 0.0 0.4 3.3 8.0 0.0 1.6 1.7 0.0 0.1 0.1 6.1 0.0 0.0 6.9 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 5.1 0.7 0.0 0.3 0.2 0.0 0.0 0.1 3.8 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 5.6 0.3 3.1 0.2 0.0 0.1 0.1 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.3 10.5 11.5 9.9 12.7 4.9 16.9 7.6 4.3 8.0 6.1 0.4 0.0 12.6 2020.2 0.0 0.6 0.9 1.1 0.6 15.9 45.6 17.0 27.2 0.0 10.2 12.9 0.0 0.0 0.2 0.0 5.9 0.5 6.7 25.4 1.0 1.0 0.0 0.0 62.0 0.5 0.2 1.8 0.0 25.8 0.0 5.4 0.0 0.0 0.1 0.0 6091.7 0.0 2.0 0.0 0.3 2.2 1.8 0.3 3.6 96.5 0.0 9.1 0.0 2369.0 1049.9 0.0 0.0 0.4 0.0 1.6 0.0 0.2 28.1 1.9 6.6 4.1 3.0 1.8 2.6 0.2 1.3 0.0 0.2 0.0 0.0 1.2 EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 55.6" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Basal prostatic cells: 47.5;Basal respiratory cells: 50.4;Endometrial ciliated cells: 43.7;Glandular and luminal cells: 53.8;Oligodendrocyte precursor cells: 48.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 69.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 40.1;SCLC-21H: 58.3;U-266/70: 110.9;U-266/84: 139.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA027024: AB_1848334, HPA059291: AB_2683967" "unprognostic (1.08e-1)" "unprognostic (5.71e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.30e-5)" "unprognostic (3.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" 12.0 1.5 12.3 2.4 14.1 0.0 11.0 15.6 12.3 55.6 11.2 9.3 0.3 17.2 3.7 34.2 34.0 1.8 5.0 10.7 11.8 4.7 2.1 2.2 0.8 14.6 14.4 0.7 1.9 9.4 5.3 6.3 13.7 23.6 3.1 1.2 31.2 9.3 2.5 5.3 1.1 1.8 11.8 0.6 8.9 5.6 13.4 18.8 14.6 3.4 6.6 4.9 16.5 11.0 0.2 4.4 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 2.5 1.9 0.3 40.1 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.1 0.3 2.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 7.7 0.1 0.0 0.6 0.1 0.0 0.1 0.8 0.5 0.0 0.0 58.3 0.0 0.0 24.8 0.0 3.0 5.3 0.2 0.0 0.0 4.5 0.3 8.8 110.9 139.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 14.1 15.6 12.3 10.7 11.8 14.6 14.4 13.7 11.8 13.4 11.0 0.4 0.0 0.0 153.8 0.9 0.6 47.5 50.4 14.8 0.4 7.8 7.6 0.5 2.8 33.0 0.0 6.2 27.7 0.0 2.5 0.0 0.9 0.2 43.7 3.9 0.6 1.2 0.0 1.5 0.0 3.0 4.8 9.2 53.8 1.3 9.8 0.4 3.3 7.4 0.0 5.1 0.6 34.6 0.0 0.4 0.3 0.0 1.1 3.6 13.1 2.6 0.0 0.0 48.7 1.0 1.1 1.7 0.7 3.4 10.9 0.0 6.3 22.2 0.4 0.0 0.3 2.8 0.2 7.4 16.0 0.3 10.8 0.6 4.2 3.6 34.6 F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 902.0;Exocrine glandular cells: 464.1;Pancreatic endocrine cells: 1755.7;Peritubular cells: 530.7;Urothelial cells: 497.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1062.0;HaCaT: 490.7;HBEC3-KT: 1270.5;U-2197: 473.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" 118.2 21.3 53.1 28.8 69.9 4.1 70.1 53.2 74.4 48.0 44.1 52.2 36.8 61.1 44.2 41.3 89.9 59.6 36.8 54.0 62.7 18.0 5.1 59.8 12.9 77.7 62.6 114.8 96.5 17.2 81.2 133.4 57.1 56.8 42.1 72.6 93.3 60.4 7.6 56.0 47.3 10.7 60.8 7.2 42.6 34.6 62.0 5.6 62.6 9.9 14.9 65.4 73.0 55.4 1062.0 1.8 2.2 0.5 108.0 53.1 57.2 147.0 87.6 155.4 167.9 18.6 220.6 0.0 73.3 183.5 33.4 490.7 13.2 1270.5 254.4 0.9 1.6 0.0 35.0 3.3 35.9 0.7 0.6 91.9 28.2 73.8 356.5 293.7 1.1 1.1 0.9 0.8 110.0 1.8 1.5 22.3 9.8 6.8 2.2 1.2 10.3 0.5 19.8 3.2 1.3 2.6 117.4 48.3 3.6 29.6 1.3 13.9 0.3 93.7 2.5 473.0 44.6 0.9 1.3 0.9 71.9 5.7 3.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 53.1 69.9 53.2 74.4 54.0 62.7 77.7 62.6 57.1 60.8 62.0 55.4 9.4 131.4 243.3 196.6 0.7 16.3 902.0 359.6 2.2 3.6 29.6 20.4 26.4 18.6 380.3 14.7 0.0 16.5 0.6 20.9 0.0 133.5 8.6 61.3 125.0 13.2 13.1 0.0 0.4 464.1 6.0 125.3 23.0 123.0 2.5 38.1 7.5 0.4 6.1 3.3 4.6 70.3 65.1 2.8 5.2 14.5 281.1 9.1 3.6 45.9 2.1 340.6 0.0 15.6 1.2 1755.7 15.5 530.7 1.2 121.6 10.1 0.4 92.0 16.1 6.6 39.3 76.7 1.7 4.4 6.4 7.5 7.7 7.3 7.9 14.3 497.9 FAM110D "FLJ14050, GRRP1" ENSG00000197245 "Family with sequence similarity 110 member D" Q8TAY7 1 26159079-26163962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 82.7;Endothelial cells: 63.5;Hepatic stellate cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "TIME: 1.2;U-2 OS: 1.4;U-937: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013664 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013664: AB_1234332" "unprognostic (7.53e-2)" "unprognostic (4.45e-3)" "unprognostic (4.80e-4)" "unprognostic (1.84e-2)" "unprognostic (1.07e-3)" "unprognostic (3.16e-3)" "unprognostic (7.67e-5)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (4.51e-2)" "unprognostic (7.29e-3)" "unprognostic (6.63e-2)" "unprognostic (9.87e-2)" "unprognostic (6.94e-2)" "unprognostic (2.91e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-1)" 10.9 1.3 4.1 0.6 3.0 0.8 8.5 3.1 3.7 4.8 2.0 2.9 1.1 7.9 0.8 1.9 7.4 2.3 6.2 3.1 3.2 4.0 0.4 4.2 1.1 4.7 3.6 1.3 2.2 1.1 1.3 0.6 4.1 3.1 0.5 0.3 2.4 0.7 4.2 3.0 3.1 2.8 4.5 0.8 3.3 0.6 4.1 0.9 4.7 2.1 0.4 4.0 3.6 3.3 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.1 0.0 0.1 0.4 0.1 0.2 1.2 0.1 1.4 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 1.3 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.2 1.0 0.4 0.1 0.2 0.0 0.0 4.1 3.0 3.1 3.7 3.1 3.2 4.7 3.6 4.1 4.5 4.1 3.3 82.7 0.0 3.4 0.3 0.9 1.0 0.9 0.0 2.2 2.3 1.3 1.8 3.1 2.8 1.3 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.4 0.2 0.5 63.5 0.0 2.7 0.4 0.0 0.0 2.5 0.0 0.2 0.0 0.3 34.6 0.0 0.0 1.7 0.7 0.0 0.0 1.3 1.8 0.5 0.6 0.4 0.0 4.7 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.4 0.0 1.4 1.8 0.2 0.7 0.8 0.9 0.3 0.3 0.5 0.0 0.3 FAM184A "C6orf60, FLJ13942" ENSG00000111879 "Family with sequence similarity 184 member A" Q8NB25 6 118959763-119149387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.3;choroid plexus: 30.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.0;Astrocytes: 261.2;Oligodendrocyte precursor cells: 88.4;Syncytiotrophoblasts: 266.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 11.8;HEK 293: 11.1;Hep G2: 7.9;JURKAT: 11.6;K-562: 10.4;SCLC-21H: 8.5;SH-SY5Y: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034571, HPA034572, HPA041955" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA034571: AB_10602498, HPA034572: AB_2674228, HPA041955: AB_2677768" "unprognostic (1.21e-1)" "unprognostic (4.11e-3)" "unprognostic (6.95e-2)" "unprognostic (3.40e-3)" "unprognostic (6.80e-2)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.18e-4)" "unprognostic (2.59e-1)" "unprognostic (3.19e-1)" "unprognostic (5.16e-4)" "unprognostic (8.38e-3)" "unprognostic (4.02e-2)" "unprognostic (9.11e-3)" "unprognostic (8.16e-3)" "unprognostic (5.70e-2)" "unprognostic (2.32e-1)" 3.1 1.6 33.3 1.3 36.3 0.2 4.7 37.3 43.3 3.6 30.5 3.5 3.0 2.5 3.0 1.4 3.2 1.8 2.5 34.3 33.0 6.7 6.3 9.9 3.5 31.9 32.4 4.5 3.2 4.8 11.0 23.0 32.4 3.9 0.9 16.3 3.3 2.8 0.9 1.7 1.6 1.6 29.1 0.6 1.7 16.9 32.6 0.6 7.0 2.2 3.5 2.4 2.1 34.5 0.1 0.3 11.8 0.9 0.3 0.3 0.0 0.6 0.4 0.5 0.9 2.0 1.1 0.9 0.0 0.2 5.3 0.0 3.4 0.0 0.2 1.3 11.1 0.1 0.9 7.9 0.2 0.0 0.6 0.4 0.1 0.1 0.0 0.3 0.0 11.6 10.4 0.7 0.3 0.3 0.4 0.1 6.0 0.6 1.3 0.0 0.1 0.0 0.1 0.1 8.5 8.0 0.7 0.6 1.8 2.2 2.1 1.4 0.3 0.8 0.5 0.2 2.9 4.9 3.3 0.3 1.5 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 33.3 36.3 37.3 43.3 34.3 33.0 31.9 32.4 32.4 29.1 32.6 34.5 21.0 48.1 103.0 261.2 0.7 2.4 5.9 0.4 11.4 35.2 3.8 8.8 6.4 2.8 17.7 3.7 29.2 61.4 0.6 0.4 17.6 1.0 22.9 2.0 2.0 5.3 6.0 0.4 66.9 1.1 18.9 11.8 1.5 0.8 6.3 8.9 1.8 4.0 5.6 13.5 55.5 0.6 0.0 0.3 1.8 9.2 3.7 1.0 0.0 34.7 0.0 11.1 0.0 88.4 20.6 0.3 1.2 7.2 2.7 1.6 0.4 3.1 37.3 28.4 6.6 45.2 4.1 61.8 16.0 4.2 3.4 266.4 5.8 1.4 0.7 2.0 FAM89A "C1orf153, MGC15887" ENSG00000182118 "Family with sequence similarity 89 member A" Q96GI7 1 231018958-231040254 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.0;placenta: 68.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 186.3;Extravillous trophoblasts: 267.5;Rod photoreceptor cells: 102.5;Syncytiotrophoblasts: 278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 145.4;SK-MEL-30: 81.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059052, HPA059578" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles" Nucleoplasm "HPA059052: AB_2683890, HPA059578: AB_2684070" "unprognostic (7.80e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-3)" "unprognostic (1.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.10e-1)" "unprognostic (8.05e-3)" "unprognostic (4.85e-1)" "unprognostic (1.54e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.87e-2)" "unprognostic (2.03e-1)" "unprognostic (2.01e-1)" "unprognostic (9.26e-2)" 60.0 18.0 16.0 4.8 15.3 5.9 36.5 20.7 16.4 11.0 21.3 4.4 1.7 7.5 1.6 6.5 7.1 5.9 10.6 14.2 23.4 22.2 9.2 19.2 5.9 22.6 21.4 6.0 10.6 6.0 5.8 68.2 20.9 7.1 2.7 17.3 5.3 4.6 5.9 30.6 4.6 4.1 21.2 17.5 7.6 3.0 25.1 2.9 5.5 6.7 4.7 8.9 9.2 19.5 0.9 13.7 6.3 13.4 15.0 3.0 145.4 7.8 5.8 2.8 5.1 21.1 12.1 0.0 1.8 5.1 16.7 8.4 12.0 1.9 2.3 42.4 28.9 6.7 0.3 0.9 57.6 5.0 35.2 50.1 26.6 0.0 13.2 0.1 7.4 15.0 53.4 8.6 2.7 5.0 3.2 8.8 9.4 12.6 4.3 16.6 20.3 16.0 10.1 14.8 5.8 16.1 2.6 1.2 81.6 13.9 0.8 29.2 1.1 22.5 0.1 0.4 14.7 18.3 23.7 11.6 6.7 9.8 45.7 1.4 0.2 0.0 0.2 0.0 0.3 0.3 0.2 0.5 0.0 0.1 0.4 0.9 0.0 0.1 0.0 0.0 0.0 0.2 16.0 15.3 20.7 16.4 14.2 23.4 22.6 21.4 20.9 21.2 25.1 19.5 82.3 0.0 2.6 3.6 4.2 30.1 22.0 0.3 8.0 48.1 3.8 5.2 3.3 7.2 0.7 0.0 77.2 186.3 4.9 0.3 3.9 2.8 1.3 1.3 39.3 44.5 0.0 14.9 1.1 3.3 267.5 11.6 0.5 2.6 4.5 0.5 10.8 11.1 51.0 8.4 10.8 0.6 0.0 19.6 2.1 3.6 2.8 8.5 21.4 22.5 0.5 26.2 1.0 10.1 2.0 4.4 0.5 1.5 1.4 30.2 0.0 5.1 0.1 102.5 0.0 9.9 8.5 4.2 11.6 1.7 32.8 278.3 5.5 0.4 1.3 15.4 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FBXL7 "FBL6, FBL7, KIAA0840" ENSG00000183580 "F-box and leucine rich repeat protein 7" Q9UJT9 5 15500180-15939795 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 976.2;Inhibitory neurons: 295.1;Oligodendrocyte precursor cells: 335.8;Oligodendrocytes: 766.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA055464 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055464: AB_2682822" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" "unprognostic (3.34e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (4.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.41e-2)" "unprognostic (4.29e-3)" "unprognostic (3.42e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.69e-4)" "unprognostic (1.94e-3)" 17.5 22.7 16.9 3.7 19.5 0.0 13.9 16.0 15.9 19.1 15.9 17.2 2.0 26.4 10.3 9.7 15.8 8.4 17.0 15.5 14.2 4.7 2.1 9.6 2.6 19.7 16.5 26.8 1.9 1.0 4.7 6.6 16.1 13.3 5.2 4.3 5.6 19.5 4.0 5.0 6.8 24.6 15.1 5.0 10.2 4.4 18.4 2.4 8.2 5.7 2.1 16.6 13.1 22.3 0.1 1.4 16.1 23.5 13.1 10.0 0.0 14.1 17.0 9.9 10.3 0.0 0.0 0.0 0.0 21.7 10.2 0.0 8.1 5.2 9.8 0.0 1.1 0.0 0.0 0.0 5.1 0.0 0.0 11.8 0.0 8.0 0.7 12.1 23.2 0.0 0.0 6.1 7.5 0.0 0.0 0.0 5.4 0.0 2.6 0.0 11.4 0.1 0.0 0.0 4.7 15.9 0.0 4.9 15.3 14.5 0.0 0.0 22.9 20.6 4.1 11.7 6.3 0.0 0.0 0.0 11.4 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 19.5 16.0 15.9 15.5 14.2 19.7 16.5 16.1 15.1 18.4 22.3 21.4 3.2 1.9 976.2 0.3 2.4 2.7 2.4 2.2 3.2 0.9 1.1 11.8 0.0 1.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 2.0 11.8 16.7 0.0 0.0 3.7 0.0 0.1 15.9 0.0 2.0 1.3 13.1 15.4 0.2 0.8 30.3 295.1 0.0 0.0 0.6 2.7 0.7 30.1 0.5 5.4 146.1 0.0 2.4 0.0 335.8 766.0 0.0 0.0 41.3 1.2 3.1 0.0 1.2 3.8 2.5 6.6 16.1 8.1 1.4 2.1 1.5 1.7 0.0 0.3 20.7 0.0 2.4 FGF2 FGFB ENSG00000138685 "Fibroblast growth factor 2" P09038 4 122826708-122898236 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 33.7;Astrocytes: 111.0;Endometrial stromal cells: 40.6;Fibroblasts: 77.1;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 243.8;BJ hTERT+: 148.4;fHDF/TERT166: 278.2;hTERT-HME1: 147.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000125, HPA065502" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Secreted in other tissues" NA NA 92500 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear bodies" "CAB000125: , HPA065502: " "unprognostic (1.53e-2)" "unprognostic (3.12e-1)" "unprognostic (1.08e-1)" "unprognostic (7.42e-2)" "unprognostic (2.10e-1)" "unprognostic (3.33e-1)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (2.82e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (9.85e-4)" "unprognostic (3.37e-1)" "unprognostic (4.61e-3)" "unprognostic (2.36e-1)" "unprognostic (1.81e-1)" "unprognostic (4.45e-2)" "unprognostic (3.45e-3)" 24.3 2.6 14.8 5.3 16.1 0.1 9.5 12.2 14.7 8.7 14.2 14.1 1.7 14.2 4.5 4.7 8.0 7.1 5.0 12.2 18.8 4.0 2.0 8.3 1.8 18.6 20.5 12.6 1.5 4.7 3.2 6.4 15.6 7.6 4.0 3.4 3.5 8.7 1.4 1.9 3.7 12.6 16.8 1.1 6.2 1.9 18.3 1.6 2.4 4.8 1.8 14.8 6.1 13.3 4.7 14.1 7.8 30.5 18.8 31.1 0.0 243.8 148.4 104.3 60.2 0.2 0.4 0.0 20.5 278.2 81.8 0.7 8.1 0.5 104.3 12.3 3.3 0.0 28.7 0.2 55.3 1.4 0.1 16.8 1.7 103.6 147.6 52.0 11.8 0.0 6.9 8.4 27.4 0.1 0.1 0.2 21.6 0.1 5.4 0.0 3.9 0.1 33.0 0.0 4.4 4.0 48.4 0.1 2.0 44.7 0.1 0.5 10.6 85.7 12.2 32.0 20.0 8.6 10.3 0.0 24.7 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 16.1 12.2 14.7 12.2 18.8 18.6 20.5 15.6 16.8 18.3 13.3 33.7 6.4 0.0 111.0 0.3 1.7 1.6 0.8 2.8 4.6 4.5 8.9 4.7 0.0 1.3 7.3 0.0 2.7 0.4 0.0 3.9 8.2 10.9 1.5 40.6 11.5 1.8 0.4 1.8 1.0 0.1 77.1 0.0 1.6 0.0 5.7 17.2 1.3 0.5 0.0 6.6 0.0 0.0 0.0 2.4 3.8 9.9 1.7 5.4 15.9 0.6 9.3 0.0 42.3 5.8 11.0 0.0 8.2 1.6 16.0 0.0 0.6 0.0 2.0 0.0 15.2 14.2 4.7 1.1 0.3 1.3 4.8 0.5 0.1 0.0 2.0 FJX1 "FLJ22416, FLJ25593" ENSG00000179431 "Four-jointed box kinase 1" Q86VR8 11 35618460-35620865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 29.0;Cytotrophoblasts: 25.6;Endometrial ciliated cells: 30.6;Endometrial stromal cells: 35.4;Granulosa cells: 31.2" "Cancer enhanced" "Detected in all" "glioma: 34.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-251 MG: 60.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059220 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA059220: AB_2683950" "unprognostic (8.99e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-3)" "unprognostic (5.20e-2)" "unprognostic (5.72e-2)" "unprognostic (9.56e-3)" "unprognostic (5.16e-2)" "unprognostic (1.06e-2)" "unprognostic (1.74e-1)" "unprognostic (4.39e-3)" "unprognostic (5.28e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (9.24e-9)" "unprognostic (1.64e-2)" "unprognostic (9.64e-2)" "unprognostic (8.35e-2)" "prognostic unfavorable (6.56e-4)" 8.9 5.9 8.4 1.7 10.4 0.1 3.5 6.8 9.2 7.8 4.4 2.1 0.3 5.2 1.5 3.8 4.9 2.3 2.5 10.2 7.1 9.5 2.2 2.8 1.1 8.2 13.1 9.2 3.5 0.6 2.3 3.4 6.6 5.2 0.2 0.7 2.5 2.2 1.1 6.0 1.3 1.6 9.6 5.0 1.6 0.7 12.0 1.0 2.9 0.3 1.7 3.8 3.3 10.1 23.3 11.4 12.0 3.8 4.1 12.6 3.7 25.4 17.3 24.1 17.2 14.5 7.1 0.0 5.7 10.2 49.6 24.3 4.2 42.6 20.4 0.3 33.0 2.1 4.4 0.6 9.7 2.7 0.1 4.8 31.8 12.7 38.1 3.9 11.1 1.2 12.5 0.1 23.6 5.4 0.8 0.0 16.4 0.1 33.6 1.4 26.6 5.4 18.6 28.5 11.2 6.4 2.7 2.1 7.5 8.7 48.2 0.5 21.7 19.0 35.5 3.7 60.9 0.0 0.0 0.0 33.9 1.1 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.4 6.8 9.2 10.2 7.1 8.2 13.1 6.6 9.6 12.0 10.1 7.8 0.0 0.0 9.4 0.2 17.5 15.8 14.0 29.0 1.8 5.3 13.3 1.2 0.0 3.9 0.0 12.5 25.6 0.0 0.1 1.9 7.6 0.3 30.6 35.4 11.8 0.0 0.0 6.6 0.2 13.9 7.2 0.0 6.5 0.0 31.2 17.9 0.4 3.6 0.0 3.9 0.0 2.0 0.6 1.7 0.1 0.6 1.1 0.0 1.0 0.0 12.5 0.0 6.6 1.7 1.4 0.0 0.7 0.0 22.9 0.0 8.0 4.3 0.5 0.0 6.0 22.3 0.6 1.0 5.6 9.5 11.9 0.4 3.1 0.0 2.5 FOXF2 "FKHL6, FREAC2" ENSG00000137273 "Forkhead box F2" Q12947 6 1389576-1395603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.2" "Cell type enhanced" "Detected in some" "Endothelial cells: 5.2;Fibroblasts: 7.9;Microglial cells: 19.7;Smooth muscle cells: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 70.4;HEK 293: 24.3;U-2197: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" "unprognostic (5.39e-2)" "unprognostic (3.32e-2)" "unprognostic (8.12e-2)" "unprognostic (1.11e-1)" "unprognostic (9.89e-3)" "unprognostic (2.53e-1)" "unprognostic (4.50e-2)" "unprognostic (8.76e-2)" "unprognostic (8.75e-7)" "unprognostic (1.03e-1)" "unprognostic (4.74e-2)" "unprognostic (2.08e-2)" "unprognostic (8.29e-2)" 1.8 0.4 8.1 1.8 6.0 0.0 2.4 5.5 10.3 1.0 5.1 40.2 6.0 0.2 0.8 9.6 0.5 1.5 0.7 6.1 5.2 0.2 0.1 17.8 0.4 10.1 6.0 0.1 1.0 0.6 7.6 9.1 10.0 10.8 9.3 0.1 1.3 0.6 1.0 1.4 18.7 3.5 5.1 0.0 17.8 0.9 7.1 0.0 3.7 3.5 1.8 11.1 2.1 6.9 1.6 3.4 1.0 0.8 3.2 4.9 0.1 15.6 70.4 6.3 2.9 0.3 0.0 0.0 3.3 4.6 6.8 11.9 12.2 0.6 2.8 0.0 24.3 0.0 5.7 0.0 6.1 0.0 0.4 0.8 5.0 0.0 5.9 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.1 0.0 0.0 0.0 6.9 0.2 0.0 3.7 0.0 5.2 1.3 0.0 0.2 0.0 5.8 11.0 28.7 2.8 0.3 0.0 0.0 0.0 4.7 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 6.0 5.5 10.3 6.1 5.2 10.1 6.0 10.0 5.1 7.1 6.9 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.0 5.2 0.0 0.0 1.1 0.0 1.5 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.4 2.5 0.1 1.8 19.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 5.5 0.2 1.5 0.3 0.1 0.1 0.1 0.0 0.0 0.0 FOXO4 "AFX1, MLLT7" ENSG00000184481 "Forkhead box O4" P98177 X 71095851-71103532 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 116.5" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 260.7;Syncytiotrophoblasts: 307.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 6 "BEWO: 159.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039560, HPA040232" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA039560: AB_2676572, HPA040232: AB_2676894" "unprognostic (4.64e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (4.79e-2)" "prognostic favorable (4.61e-4)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (7.18e-2)" "unprognostic (2.13e-2)" "unprognostic (8.16e-2)" "prognostic favorable (3.46e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-3)" 15.8 33.6 73.9 6.5 80.6 22.0 13.9 58.9 68.7 12.9 43.1 22.1 11.0 17.1 16.4 12.0 17.6 9.4 18.2 58.3 61.8 9.4 7.2 10.0 7.1 71.7 70.5 23.2 12.7 16.0 7.0 116.5 65.3 14.3 8.0 7.5 16.7 19.2 67.3 15.1 14.3 8.2 62.3 13.9 13.5 17.3 68.8 14.5 10.9 49.4 6.4 17.2 13.2 81.6 4.6 1.2 3.4 4.9 7.9 5.7 159.1 3.4 3.9 1.8 4.5 3.3 6.5 5.9 4.7 4.5 1.9 2.1 8.8 4.2 2.2 6.0 13.7 8.5 27.3 5.0 4.8 4.9 6.9 5.1 9.7 1.7 1.1 7.9 4.7 8.4 17.5 12.5 0.8 0.9 8.6 8.0 16.9 11.5 5.6 5.7 8.5 10.1 3.0 2.6 2.8 7.3 7.1 1.1 8.3 24.7 1.9 3.1 4.3 1.1 2.3 8.3 0.8 7.7 4.3 1.0 4.3 13.6 1.3 0.0 0.1 1.0 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.1 0.4 0.9 0.2 0.1 0.0 0.3 0.3 73.9 80.6 58.9 68.7 58.3 61.8 71.7 70.5 65.3 62.3 68.8 81.6 10.1 0.0 2.7 0.3 3.8 5.4 3.9 0.6 9.1 1.3 8.2 7.7 6.6 5.7 1.5 9.2 4.2 260.7 6.5 20.6 1.9 2.7 0.3 3.2 2.8 6.1 6.1 17.7 0.8 3.0 24.3 4.0 5.1 3.1 2.5 3.1 5.0 2.9 22.3 1.7 0.8 12.2 0.0 7.1 5.2 1.4 6.8 4.4 3.6 1.0 2.6 4.4 4.1 1.0 2.2 3.1 8.6 15.4 7.3 2.5 17.1 4.4 1.5 0.8 6.6 4.0 3.8 0.6 0.4 6.0 3.4 307.8 7.0 48.3 7.4 3.8 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.9;Astrocytes: 34.6;Early spermatids: 26.6;Endothelial cells: 26.9;Hepatic stellate cells: 41.7;Muller glia cells: 47.4;Oligodendrocytes: 69.3" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 133.0;ASC TERT1: 128.8;HSkMC: 102.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 157.4 4.9 45.1 1.7 55.8 2.7 87.2 62.5 49.3 12.3 14.4 21.7 3.0 11.4 11.9 12.4 24.9 5.6 18.1 47.9 90.8 11.8 4.0 9.4 4.1 137.6 60.4 22.3 3.6 2.4 3.5 32.3 130.8 6.0 3.9 13.4 25.5 4.7 36.3 41.7 21.2 7.0 102.4 12.3 15.3 9.1 62.8 4.0 18.3 35.3 1.3 33.0 22.8 141.7 0.4 1.3 0.9 1.0 133.0 128.8 0.3 3.4 2.5 0.4 1.3 0.0 0.5 0.5 1.9 7.8 2.3 0.8 0.5 1.4 2.0 0.6 1.4 1.1 1.9 0.0 7.4 1.5 0.4 102.8 0.0 1.2 1.8 2.4 2.8 0.7 0.2 3.0 1.1 1.9 0.0 2.1 0.5 0.8 1.1 0.3 1.1 24.1 0.5 0.5 0.4 0.3 0.4 1.0 0.6 0.6 0.7 1.8 3.9 0.6 4.3 26.8 0.6 1.4 5.1 1.4 2.5 0.4 0.4 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 45.1 55.8 62.5 49.3 47.9 90.8 137.6 60.4 130.8 102.4 62.8 141.7 103.9 0.0 1.7 34.6 0.1 0.5 0.4 0.0 0.0 3.8 1.1 0.9 2.8 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 26.6 0.5 3.3 26.9 0.0 0.0 4.9 0.0 0.1 24.7 0.0 1.0 1.3 0.1 41.7 1.8 0.1 0.0 3.9 0.0 0.0 0.8 2.1 16.7 1.8 0.5 0.0 22.5 0.1 47.4 0.0 5.0 69.3 0.2 0.0 0.7 1.8 2.1 0.0 0.1 0.0 3.2 0.0 7.3 2.1 25.5 0.5 0.1 0.9 0.0 0.2 0.3 0.0 0.3 GDI1 "FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGDIA, XAP-4" ENSG00000203879 "GDP dissociation inhibitor 1" P31150 X 154436913-154443467 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 438.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012979, HPA049290, HPA057668" Enhanced Approved Cytosol NA NA 31000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol "CAB012979: AB_2533970, HPA049290: AB_2680700, HPA057668: AB_2683498" "prognostic unfavorable (6.84e-4)" "unprognostic (1.13e-2)" "prognostic unfavorable (3.83e-5)" "unprognostic (3.53e-1)" "unprognostic (1.22e-1)" "unprognostic (1.92e-3)" "unprognostic (1.31e-3)" "unprognostic (1.36e-1)" "unprognostic (1.46e-2)" "unprognostic (1.30e-1)" "unprognostic (2.98e-3)" "unprognostic (3.86e-2)" "unprognostic (3.88e-3)" "unprognostic (1.70e-1)" "unprognostic (8.12e-2)" "unprognostic (1.92e-2)" "unprognostic (1.72e-1)" 77.3 85.9 351.5 54.9 381.7 41.2 67.4 309.6 438.5 99.7 214.0 91.8 36.7 92.2 46.2 57.5 94.6 47.3 99.1 391.8 349.9 74.4 53.9 90.1 53.9 344.5 312.7 120.0 54.7 63.4 176.0 60.4 349.5 74.9 41.7 130.9 49.7 69.5 62.9 61.6 67.5 78.9 311.4 89.4 68.5 54.1 330.6 58.7 63.0 70.8 51.1 89.2 81.2 366.2 100.2 88.9 195.9 164.6 77.7 91.4 64.5 149.6 91.1 140.4 146.0 52.6 51.1 79.5 149.3 139.4 213.2 79.7 172.7 83.9 96.5 147.5 93.8 25.0 142.6 35.5 113.5 24.6 90.5 94.7 101.3 163.4 99.6 154.6 92.4 95.7 31.1 120.5 169.4 99.2 77.9 62.1 53.0 106.1 168.8 77.6 51.6 45.0 98.8 46.5 272.5 210.3 67.6 86.1 109.0 150.3 50.9 42.5 110.4 131.9 116.8 138.4 212.0 182.1 202.0 128.3 140.7 54.5 162.5 23.7 8.4 26.9 12.1 12.6 18.0 9.9 13.0 12.0 7.0 10.1 10.0 10.1 30.0 8.7 21.3 12.1 16.2 7.3 351.5 381.7 309.6 438.5 391.8 349.9 344.5 312.7 349.5 311.4 330.6 366.2 39.3 16.0 27.4 30.3 35.9 27.1 24.8 48.3 33.6 71.3 24.1 25.7 62.6 24.3 29.0 27.6 25.0 22.7 27.0 31.4 31.3 39.4 2.9 33.1 41.1 35.3 90.8 9.2 48.8 31.3 39.3 37.5 37.8 34.3 33.7 29.7 30.4 17.7 36.3 60.6 43.2 24.8 65.1 35.9 40.9 6.0 37.6 35.5 17.8 22.5 59.0 37.7 19.6 33.2 46.4 50.2 25.9 39.9 35.7 27.4 24.3 25.5 46.8 37.1 52.6 29.5 49.8 33.9 66.6 20.7 30.3 49.5 43.2 22.0 15.0 26.2 GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 30.4;Fibroblasts: 77.9;Skeletal myocytes: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cell line enhanced" "Detected in many" "ASC diff: 119.1;ASC TERT1: 202.3;GAMG: 152.5;HSkMC: 130.7;hTEC/SVTERT24-B: 248.0;U-87 MG: 426.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" 112.4 7.0 14.2 18.6 14.8 0.1 23.0 19.7 17.6 24.8 14.1 18.0 1.6 15.9 7.7 5.7 35.8 16.4 27.8 14.9 16.8 6.8 2.1 25.2 2.8 27.8 15.7 33.4 12.4 4.6 5.1 6.5 21.5 15.6 3.2 2.9 7.1 8.2 4.6 8.4 11.3 11.3 16.8 1.9 14.6 8.6 15.7 1.2 10.8 7.1 3.5 38.3 17.9 20.4 0.1 27.7 21.5 28.0 119.1 202.3 2.3 3.5 0.7 2.3 0.8 0.7 0.1 0.0 1.4 23.2 152.5 0.4 11.8 0.2 1.4 2.6 4.2 0.0 13.7 0.0 49.4 0.0 0.2 130.7 1.0 248.0 0.7 41.7 40.7 1.0 0.0 0.4 107.7 4.2 0.1 0.0 45.7 0.3 12.3 0.6 0.2 0.0 0.0 0.0 1.0 1.6 43.0 0.8 1.4 25.0 1.9 0.3 19.5 67.9 10.7 44.3 52.2 0.1 0.1 0.0 426.7 0.0 1.5 0.0 0.0 0.0 0.7 0.0 3.5 0.0 0.3 1.2 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 14.2 14.8 19.7 17.6 14.9 16.8 27.8 15.7 21.5 16.8 15.7 20.4 4.1 3.2 4.8 13.4 0.8 7.4 0.4 0.2 3.4 0.0 3.2 6.3 3.0 5.7 3.2 1.8 0.0 1.1 3.5 0.4 1.9 1.0 5.7 2.0 30.4 1.9 0.0 0.0 20.0 0.8 0.5 77.9 6.6 1.9 1.3 0.4 1.4 0.0 0.5 0.0 12.1 0.5 0.0 0.3 9.6 3.5 10.2 1.7 8.8 4.7 0.0 6.1 0.0 10.6 6.5 0.4 0.0 18.8 2.5 1.7 0.0 0.4 1.5 0.1 0.0 27.3 17.6 10.1 8.3 1.7 4.3 2.7 8.9 0.0 0.1 0.6 GOLM1 "bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73" ENSG00000135052 "Golgi membrane protein 1" Q8NBJ4 9 86026146-86100173 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 396.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 362.8;Early spermatids: 339.0;Gastric mucus-secreting cells: 245.6;Ionocytes: 325.5;Late spermatids: 391.6;Pancreatic endocrine cells: 282.9;Paneth cells: 265.2;Undifferentiated cells: 245.6" "Cancer enhanced" "Detected in all" "prostate cancer: 343.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.9;classical monocyte: 3.6;gdT-cell: 3.5;intermediate monocyte: 2.6;neutrophil: 4.2;non-classical monocyte: 4.2;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 372.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010638, HPA011929, CAB015341" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA 81000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "CAB015341: AB_2113334, HPA010638: AB_1849886, HPA011929: AB_1849888" "unprognostic (1.47e-1)" "unprognostic (2.31e-2)" "unprognostic (1.10e-1)" "prognostic favorable (8.14e-5)" "unprognostic (1.97e-1)" "unprognostic (4.40e-3)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.89e-3)" "unprognostic (2.81e-1)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (5.59e-3)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.87e-3)" "unprognostic (1.23e-1)" 22.2 159.8 72.5 33.8 78.8 6.6 39.5 69.2 84.5 70.0 99.0 195.7 235.1 40.1 15.7 13.6 38.1 131.0 12.7 72.1 93.8 74.7 19.0 14.7 9.7 73.4 76.1 36.9 41.6 37.6 36.4 17.2 69.9 143.2 163.9 25.5 173.4 10.5 9.4 14.9 61.3 28.4 80.1 41.7 396.2 17.4 108.0 45.4 68.1 4.8 5.6 38.3 14.9 79.2 146.0 139.5 102.4 116.7 129.3 74.3 108.0 64.8 46.6 99.9 80.5 69.4 282.9 2.7 62.6 126.2 96.6 109.4 63.7 64.1 71.9 5.0 101.2 45.3 89.1 3.4 76.8 67.3 34.9 113.4 34.2 94.1 34.0 124.9 172.9 21.2 28.7 4.2 57.3 68.4 8.3 49.6 161.9 188.9 99.6 42.9 116.9 21.8 166.0 61.2 115.1 72.0 88.2 189.0 73.8 66.1 106.7 68.1 110.5 25.9 72.6 79.3 78.3 372.3 37.4 0.9 112.2 29.8 57.8 1.9 3.6 0.4 3.5 2.6 0.4 0.6 0.2 0.5 0.4 0.6 0.4 0.7 4.2 0.7 4.2 1.5 0.1 1.8 72.5 78.8 69.2 84.5 72.1 93.8 73.4 76.1 69.9 80.1 108.0 79.2 13.8 9.6 15.3 30.3 1.7 2.3 10.8 11.3 4.6 20.1 41.4 21.1 4.9 80.1 80.9 35.0 8.4 8.4 10.7 362.8 25.4 168.4 339.0 78.0 49.8 20.5 73.1 11.2 47.0 222.2 35.0 30.4 245.6 56.8 1.3 65.9 8.6 11.1 11.8 67.3 43.2 95.5 325.5 5.0 2.6 391.6 18.3 6.6 23.2 6.5 6.9 16.9 12.3 82.0 19.3 282.9 265.2 13.2 3.2 72.6 71.8 16.0 78.6 6.7 0.0 13.5 19.5 10.3 38.7 2.9 1.0 6.4 5.2 60.7 245.6 29.1 GPIHBP1 "GPI-HBP1, LOC338328" ENSG00000277494 "Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1" Q8IV16 8 143213218-143217170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;breast: 54.5" "Cell type enriched" "Detected in some" 4 "Adipocytes: 356.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Karpas-707: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066302 Enhanced "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA066302: AB_2685654" "unprognostic (2.05e-1)" "unprognostic (3.11e-2)" "unprognostic (1.71e-3)" "unprognostic (2.43e-3)" "unprognostic (1.58e-1)" "unprognostic (9.50e-2)" "unprognostic (1.75e-3)" "unprognostic (8.01e-2)" "unprognostic (2.04e-1)" "unprognostic (1.30e-1)" "unprognostic (9.31e-2)" "unprognostic (8.69e-2)" "unprognostic (5.06e-3)" "unprognostic (9.65e-3)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-3)" 90.7 4.9 12.9 0.4 23.7 0.1 54.5 22.7 27.2 8.7 7.5 5.3 0.6 11.4 0.2 3.5 11.7 6.5 38.6 13.3 17.9 11.0 1.6 27.4 2.4 35.8 20.8 6.6 1.8 1.1 3.4 6.5 32.9 3.9 0.5 0.1 4.1 1.6 30.2 7.4 3.7 2.4 18.0 19.3 4.1 2.0 22.8 1.9 5.5 29.7 1.0 10.5 7.9 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 23.7 22.7 27.2 13.3 17.9 35.8 20.8 32.9 18.0 22.8 53.5 356.5 0.0 3.2 0.0 0.5 1.5 0.1 0.0 1.2 0.0 1.0 0.6 4.3 0.0 0.6 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 77.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 1.3 0.0 35.7 0.4 0.0 0.0 0.1 0.0 0.0 0.8 2.1 0.6 1.5 0.4 0.0 8.4 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 5.4 3.0 0.0 0.7 0.2 1.1 0.0 0.4 1.1 0.0 0.2 GPR146 PGR8 ENSG00000164849 "G protein-coupled receptor 146" Q96CH1 7 1044546-1059261 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "adipose tissue: 47.9" "Cell type enhanced" "Detected in many" "Adipocytes: 96.3;Endothelial cells: 45.3;Extravillous trophoblasts: 243.2;Syncytiotrophoblasts: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 95.2;naive CD4 T-cell: 25.6" "Group enriched" "Detected in many" 4 "granulocytes: 95.2;T-cells: 25.6" "Cell line enhanced" "Detected in many" "BEWO: 23.0;NB-4: 7.1" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.39e-2)" "unprognostic (7.83e-2)" "unprognostic (6.27e-4)" "unprognostic (5.51e-3)" "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (2.69e-1)" "unprognostic (2.99e-2)" "unprognostic (3.48e-3)" "unprognostic (2.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (3.27e-3)" "unprognostic (1.41e-1)" "unprognostic (4.19e-2)" "unprognostic (1.03e-2)" 47.9 2.6 16.9 2.0 17.2 9.0 41.8 17.0 20.9 10.0 22.1 14.1 2.8 13.2 2.8 4.7 12.3 7.5 13.2 13.6 15.4 5.3 20.4 24.9 4.1 18.6 18.4 7.4 5.9 1.6 3.4 10.2 18.7 7.2 1.0 3.6 9.6 5.5 10.7 11.2 8.1 3.5 16.6 6.7 12.9 2.6 21.8 1.7 11.5 8.8 1.2 13.2 8.7 17.3 1.2 1.0 0.4 1.0 1.3 0.3 23.0 0.1 0.9 0.2 1.1 0.8 1.1 0.4 0.7 0.1 3.5 0.8 0.0 0.3 0.1 0.8 0.9 1.7 0.7 1.9 1.5 0.1 0.2 0.5 0.0 0.7 0.0 2.4 1.7 0.6 1.1 1.2 0.2 0.7 0.0 7.1 1.6 1.3 0.6 5.5 0.0 1.5 0.3 0.1 1.2 1.7 1.8 0.2 2.0 0.9 1.1 2.2 0.5 1.0 1.1 1.6 0.8 1.9 2.1 0.1 6.1 2.2 2.1 0.0 0.2 95.2 0.6 0.1 1.2 0.0 8.4 0.7 1.7 0.1 25.6 4.8 0.1 1.3 0.3 14.3 14.5 4.3 16.9 17.2 17.0 20.9 13.6 15.4 18.6 18.4 18.7 16.6 21.8 17.3 96.3 0.0 2.8 7.2 3.3 1.8 0.8 1.8 1.2 3.7 7.6 3.4 0.3 1.5 2.1 1.8 0.0 9.3 1.4 0.3 1.9 1.0 0.1 3.2 0.4 45.3 4.2 30.5 0.9 0.6 243.2 4.8 2.0 3.7 2.5 1.7 16.4 21.3 10.9 3.3 1.4 0.3 2.0 0.6 6.1 1.1 3.1 1.7 3.6 3.7 0.2 21.2 2.1 4.5 1.7 0.7 0.3 3.4 0.9 0.7 0.8 3.4 0.0 5.7 0.0 2.3 1.4 0.5 1.5 0.4 2.3 82.4 2.5 0.9 1.0 0.4 GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.1;Distal tubular cells: 41.1;Extravillous trophoblasts: 26.5;Hofbauer cells: 39.9;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.0;myeloid DC: 5.9;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019306: , HPA011326: AB_1847629" "unprognostic (1.08e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" "unprognostic (6.36e-3)" "unprognostic (6.70e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-3)" "unprognostic (1.48e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" 13.5 7.8 16.4 2.9 16.7 0.5 7.6 13.3 18.0 17.3 9.2 6.4 7.7 24.8 15.3 3.6 14.3 8.5 9.7 18.1 15.0 13.3 4.5 4.4 5.8 19.4 18.7 16.9 2.6 7.3 7.0 35.0 16.1 7.5 2.4 6.3 3.1 21.1 7.8 3.0 26.8 15.1 16.5 1.8 3.9 12.9 14.1 5.8 14.5 5.2 3.8 15.0 10.1 26.6 31.4 21.7 9.6 41.2 51.4 28.6 16.4 24.1 63.6 24.5 34.3 22.9 1.1 0.5 20.6 66.4 81.7 20.5 5.8 105.4 42.8 0.1 2.1 0.8 39.3 48.0 43.0 0.1 1.5 31.3 75.3 43.5 103.1 73.0 42.3 13.8 3.0 5.2 55.3 0.4 1.9 0.8 10.2 0.1 15.7 0.2 33.6 0.0 74.5 21.9 0.4 60.0 36.5 0.6 42.3 24.3 2.2 2.8 27.9 23.1 39.7 31.6 29.2 2.4 0.6 15.5 69.8 0.1 5.8 0.0 1.9 0.0 0.0 0.2 0.0 9.0 0.1 0.0 5.9 8.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 16.4 16.7 13.3 18.0 18.1 15.0 19.4 18.7 16.1 16.5 14.1 26.6 1.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.0 0.0 0.6 5.5 0.0 168.1 0.0 0.0 41.1 1.9 0.0 0.7 16.9 1.3 0.0 0.0 0.0 0.9 26.5 4.3 0.0 1.0 0.0 4.8 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 8.8 1.5 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 104.7 0.7 0.9 0.0 0.0 GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807811 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 20.2;Ductal cells: 22.9;Glandular and luminal cells: 15.5;Proximal tubular cells: 22.2;Smooth muscle cells: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "intermediate monocyte: 7.2;non-classical monocyte: 23.9" "Lineage enriched" "Detected in many" 13 "monocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 46.0;Karpas-707: 23.7;MOLT-4: 29.9;RPTEC TERT1: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010890, HPA020870" Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB010890: AB_259911, HPA020870: AB_1850444" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (9.10e-3)" "unprognostic (4.69e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (6.69e-3)" "unprognostic (3.03e-3)" "unprognostic (1.47e-1)" "unprognostic (8.37e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (7.35e-3)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.14e-1)" "unprognostic (6.36e-3)" 13.8 7.1 23.6 15.6 30.0 2.2 10.0 5.3 36.6 12.6 0.0 28.9 5.8 16.4 6.0 8.1 13.7 13.3 18.7 30.1 28.2 13.2 7.7 16.5 10.4 9.8 13.9 5.8 10.9 50.3 6.0 43.6 22.8 13.6 8.7 34.7 5.5 12.2 5.9 3.5 11.1 25.0 6.4 11.0 13.8 2.4 14.8 7.2 7.3 14.9 7.3 10.0 11.1 17.0 0.0 0.5 6.5 0.0 2.2 11.4 0.0 2.0 3.6 0.2 0.1 0.0 0.0 0.0 3.0 1.1 5.0 0.1 13.6 0.3 0.8 0.0 4.6 46.0 0.0 0.0 1.2 0.0 0.0 5.1 0.4 0.0 0.2 4.2 0.1 10.2 0.0 23.7 3.0 2.1 29.9 0.1 0.4 0.0 3.2 3.5 0.9 0.7 42.9 4.4 0.7 7.8 0.0 0.2 0.0 6.4 0.0 0.0 0.0 7.3 1.6 12.4 9.5 0.3 0.0 0.0 15.6 0.0 0.0 1.4 0.5 0.5 0.0 7.2 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.0 0.5 1.3 23.9 1.6 0.0 5.8 23.6 30.0 5.3 36.6 30.1 28.2 9.8 13.9 22.8 6.4 14.8 17.0 20.2 6.4 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.2 0.0 0.0 0.0 9.2 0.0 1.1 1.1 0.0 5.9 22.9 0.0 3.7 4.3 3.4 0.0 0.0 0.0 4.2 0.2 5.4 0.0 15.5 1.3 4.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.7 0.4 0.7 0.0 0.0 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 156.3" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Enteroendocrine cells: 20.4;Granulosa cells: 10.2;Hepatocytes: 20.2" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.1;CACO-2: 30.4;Hep G2: 32.6;NTERA-2: 38.4;SK-MEL-30: 87.6;SuSa: 59.0" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: AB_2685323" "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favorable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 156.3 2.2 10.3 1.9 10.8 0.2 38.9 18.4 8.8 3.0 8.5 3.9 1.5 6.6 1.0 0.9 5.1 2.2 1.4 11.2 18.9 2.0 18.5 0.5 0.6 29.4 24.5 2.5 5.4 1.0 0.8 2.1 27.3 4.0 2.8 1.4 4.7 6.6 0.3 1.9 2.1 3.7 36.0 0.3 4.5 0.9 13.7 0.4 1.7 0.5 0.3 3.7 2.0 35.4 0.1 11.5 39.1 0.2 20.5 0.0 28.5 2.0 6.3 6.1 8.2 30.4 0.6 0.0 3.1 5.2 6.6 0.0 22.5 0.5 6.8 0.2 6.3 0.1 0.7 32.6 6.7 0.0 8.9 8.1 0.4 1.0 0.0 0.2 0.0 0.0 0.3 0.1 6.6 1.9 0.0 1.0 38.4 0.4 0.2 6.1 13.0 0.0 0.0 0.1 0.0 0.7 0.1 0.3 87.6 59.0 4.1 25.4 0.0 0.0 6.7 3.8 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.3 10.8 18.4 8.8 11.2 18.9 29.4 24.5 27.3 36.0 13.7 35.4 0.3 0.0 0.0 10.7 0.2 0.4 1.1 0.5 0.0 1.2 2.1 0.8 1.2 4.3 0.2 0.0 4.2 6.0 0.0 1.2 5.9 1.0 0.4 3.8 1.0 0.3 20.4 0.0 5.9 4.0 7.9 1.6 4.6 0.7 0.0 10.2 0.0 20.2 1.1 0.0 4.9 1.7 0.0 1.0 0.0 0.5 0.6 0.1 3.6 0.0 0.0 1.6 0.0 0.5 0.1 2.1 0.6 3.0 0.0 1.0 0.4 2.4 1.1 0.1 0.0 0.3 1.2 0.3 1.5 0.0 0.3 2.3 0.0 3.2 3.5 0.7 H2BU1 HIST3H2BB ENSG00000196890 "H2B.U histone 1" Q8N257 1 228458107-228460470 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5;cervix: 4.7;vagina: 3.5" "Cell type enhanced" "Detected in single" "Syncytiotrophoblasts: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "T-47d: 3.0;U-266/70: 15.1;U-266/84: 3.8" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (5.53e-3)" "unprognostic (2.41e-1)" "unprognostic (3.39e-3)" "unprognostic (5.25e-2)" "unprognostic (8.20e-3)" "unprognostic (8.78e-3)" "unprognostic (1.74e-2)" "unprognostic (2.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.96e-2)" "unprognostic (1.05e-1)" "unprognostic (2.34e-2)" "unprognostic (9.74e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-1)" "unprognostic (2.59e-1)" 0.7 0.7 0.8 0.0 0.5 0.2 0.2 3.5 0.7 4.7 0.1 0.2 0.1 0.1 0.1 1.4 1.0 0.0 0.8 0.4 1.6 0.6 0.1 0.9 0.1 0.9 0.8 0.6 0.1 0.0 0.9 0.0 1.1 0.8 0.0 0.5 0.3 0.0 0.1 1.2 0.3 0.0 0.4 0.8 0.3 0.2 1.9 0.0 0.4 0.0 0.1 0.4 3.5 0.5 0.2 0.2 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.4 0.8 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.1 0.4 0.5 0.0 0.6 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.3 0.0 0.3 0.2 0.2 0.0 0.0 0.7 0.0 0.1 1.2 0.4 0.8 0.3 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.4 0.0 15.1 3.8 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.6 0.1 0.3 0.2 0.1 0.1 0.8 0.5 3.5 0.7 0.4 1.6 0.9 0.8 1.1 0.4 1.9 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 HAUS7 "UCHL5IP, UIP1" ENSG00000213397 "HAUS augmin like complex subunit 7" Q99871 X 153447666-153495516 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003614 Approved "Plasma membrane,Centrosome" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome" "HPA003614: AB_1080368" "unprognostic (2.06e-1)" "prognostic favorable (6.12e-4)" "unprognostic (3.81e-2)" "unprognostic (3.21e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-2)" "unprognostic (1.75e-2)" "unprognostic (7.50e-2)" "unprognostic (1.56e-1)" "unprognostic (3.39e-1)" "unprognostic (4.65e-3)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.98e-1)" "unprognostic (1.15e-1)" "unprognostic (4.25e-2)" "unprognostic (1.09e-2)" 19.0 13.0 29.1 9.2 31.3 11.0 16.2 26.3 54.0 42.3 24.3 15.9 7.1 17.8 15.1 11.4 21.3 13.2 23.5 32.3 26.3 25.2 13.6 19.5 14.4 28.3 27.0 16.0 8.2 5.0 11.9 12.3 28.4 22.5 5.8 3.0 12.5 17.9 12.0 44.7 13.3 11.5 26.4 28.5 11.5 12.6 29.0 10.4 19.2 9.2 9.5 17.4 21.7 32.3 28.2 44.9 24.1 51.2 8.9 14.1 37.2 17.8 12.1 30.1 51.4 36.2 17.3 25.5 59.2 18.5 43.1 32.0 39.6 29.4 15.6 23.6 59.6 19.3 33.5 26.9 9.3 26.9 35.5 21.1 7.4 29.5 16.4 13.1 22.4 32.5 21.7 17.6 15.7 68.9 41.7 60.5 15.7 67.5 65.8 36.5 30.2 47.0 10.2 17.3 25.1 20.5 10.3 27.4 9.6 8.9 10.8 20.8 10.7 27.1 42.9 50.8 36.1 24.0 33.7 97.6 11.7 68.9 34.6 14.8 53.2 22.7 32.6 66.7 34.5 44.0 36.1 33.6 46.7 36.5 35.2 32.2 6.7 39.1 62.0 26.0 33.8 34.3 29.1 31.3 26.3 54.0 32.3 26.3 28.3 27.0 28.4 26.4 29.0 32.3 9.4 6.4 8.1 45.4 5.3 7.1 1.6 3.6 1.2 2.1 2.7 3.0 2.5 4.3 2.6 0.0 4.2 12.6 6.0 9.3 5.9 10.4 0.1 1.0 1.8 5.6 2.4 6.6 11.9 8.0 24.6 6.3 3.6 0.7 19.7 1.6 15.4 4.2 12.2 3.3 4.9 13.8 4.1 10.0 6.8 0.5 5.9 5.0 3.6 4.7 13.4 2.0 12.3 31.7 3.5 7.4 7.7 7.5 2.5 3.3 6.9 14.9 3.5 1.9 6.6 1.9 6.5 2.2 6.7 1.3 4.7 9.3 4.9 1.7 14.9 1.5 HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 331.5;Hepatic stellate cells: 99.2;Inhibitory neurons: 375.4;Oligodendrocyte precursor cells: 143.2;Oligodendrocytes: 460.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.7;non-classical monocyte: 3.7" "Group enriched" "Detected in many" 8 "granulocytes: 4.7;monocytes: 3.7" "Cell line enhanced" "Detected in many" "HDLM-2: 30.1;hTEC/SVTERT24-B: 16.3;HUVEC TERT2: 20.9;SCLC-21H: 31.6;TIME: 26.3;U-138 MG: 21.7" "Low region specificity" "Detected in all" HPA034609 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034609: AB_10669993" "unprognostic (2.65e-2)" "unprognostic (3.89e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (2.55e-1)" "unprognostic (4.28e-2)" "unprognostic (7.63e-3)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (7.05e-2)" "unprognostic (4.16e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (8.05e-3)" "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" 4.1 1.5 2.4 1.2 3.5 0.1 1.7 4.4 6.1 2.2 0.0 0.4 0.4 0.8 0.3 3.1 3.5 2.1 8.1 3.3 0.0 1.6 2.7 5.3 2.0 1.1 0.8 0.2 0.6 4.3 1.2 7.4 2.1 0.4 0.4 2.7 0.9 0.5 1.4 0.8 0.5 1.3 0.0 6.0 0.9 3.5 1.7 0.8 3.8 3.5 2.4 1.0 0.6 8.2 0.1 1.4 2.3 0.0 1.4 4.2 1.6 2.7 7.3 2.1 2.6 0.3 0.1 1.4 0.5 13.4 3.3 3.2 0.9 0.1 4.5 30.1 1.6 0.0 2.3 0.2 0.2 0.5 0.3 1.0 1.3 16.3 5.7 4.1 20.9 0.0 0.2 0.1 6.7 1.8 0.0 0.7 2.5 0.2 1.0 0.0 0.5 0.0 0.1 0.0 31.6 2.5 2.0 0.5 0.0 0.4 0.1 0.2 26.3 21.7 1.4 4.6 0.7 0.2 0.0 1.3 5.4 0.1 0.2 0.1 0.3 0.8 0.0 1.1 0.0 0.4 0.0 0.0 0.4 0.5 0.0 0.0 4.7 0.0 3.7 0.0 0.0 0.1 2.4 3.5 4.4 6.1 3.3 0.0 1.1 0.8 2.1 0.0 1.7 8.2 61.2 0.0 12.1 12.7 3.6 2.2 0.3 0.1 3.4 9.5 1.1 0.8 18.7 0.0 0.1 0.0 0.0 0.2 0.7 0.6 0.0 0.1 11.1 0.4 1.6 34.2 2.4 0.0 331.5 0.0 0.3 4.2 0.5 0.3 1.3 4.9 99.2 1.5 0.1 0.0 375.4 0.6 0.0 7.2 3.0 5.3 0.0 1.4 3.6 14.0 1.2 12.0 0.0 143.2 460.7 0.1 0.0 2.6 3.4 0.4 0.0 0.1 1.0 1.1 0.0 1.2 2.2 0.5 6.1 9.2 1.6 0.1 1.4 0.7 0.1 0.6 HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 90.1;Cardiomyocytes: 90.5;Cone photoreceptor cells: 264.8;Endothelial cells: 121.5;Hepatic stellate cells: 130.3;Microglial cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 174.1;HHSteC: 241.5;hTERT-RPE1: 351.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 510000000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" 30.1 9.9 19.3 19.2 23.2 1.9 14.8 27.0 15.0 20.8 28.3 11.9 8.0 19.2 6.2 16.1 13.2 38.9 67.3 14.3 22.7 15.2 7.5 55.1 16.5 32.0 28.1 12.4 31.6 16.1 3.6 33.4 28.6 13.9 12.2 46.8 7.7 14.6 14.3 5.2 9.4 25.4 27.3 17.9 9.8 13.5 30.3 8.6 52.2 24.2 15.7 30.0 10.1 30.6 7.0 7.1 54.7 4.2 73.2 58.7 21.1 64.9 90.1 72.6 83.5 58.5 1.0 2.8 43.8 174.1 52.3 15.3 7.4 31.6 97.9 6.5 3.7 1.3 42.3 8.4 241.5 1.8 80.6 77.8 10.1 87.4 21.5 351.3 69.3 5.0 0.1 1.0 25.7 1.3 2.8 0.1 10.1 0.1 5.5 4.8 41.0 0.2 14.6 1.2 1.0 5.6 134.8 10.6 6.4 55.1 24.2 4.3 93.9 37.7 41.3 150.5 29.1 6.9 19.7 0.4 76.8 6.5 82.4 1.1 0.1 0.0 1.9 1.7 1.1 0.5 0.6 1.7 0.4 0.3 1.2 0.8 0.0 3.9 1.9 0.4 0.2 0.5 19.3 23.2 27.0 15.0 14.3 22.7 32.0 28.1 28.6 27.3 30.3 30.6 90.1 86.6 5.8 28.7 4.9 5.0 8.0 25.4 6.8 6.1 2.4 5.7 90.5 7.2 6.5 27.6 264.8 1.8 19.2 0.5 0.0 32.0 7.0 4.0 20.1 121.5 0.0 6.1 0.9 6.4 65.3 44.8 1.1 2.2 26.6 24.9 130.3 3.5 6.8 1.7 14.9 0.5 4.1 18.4 7.3 9.4 5.0 7.1 7.2 92.8 4.0 6.0 35.0 13.0 57.6 6.4 0.1 13.9 8.6 5.2 0.8 1.3 1.0 66.8 0.0 24.0 28.7 1.0 1.1 2.7 4.4 3.3 14.2 3.1 0.1 1.3 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 HIGD1B "CLST11240, CLST11240-15" ENSG00000131097 "HIG1 hypoxia inducible domain family member 1B" Q9P298 17 44846353-44850476 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.6;choroid plexus: 65.0;placenta: 105.2" "Group enriched" "Detected in some" 5 "Sertoli cells: 762.6;Smooth muscle cells: 209.3" "Cancer enhanced" "Detected in all" "glioma: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA079501 Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA079501: " "unprognostic (6.85e-2)" "unprognostic (9.41e-2)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (8.46e-2)" "unprognostic (2.37e-2)" "unprognostic (4.98e-3)" "unprognostic (3.61e-1)" "unprognostic (1.18e-2)" "unprognostic (3.98e-1)" "unprognostic (6.19e-2)" "unprognostic (3.56e-1)" "unprognostic (1.61e-3)" "unprognostic (5.23e-3)" "unprognostic (8.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.52e-2)" 11.7 0.5 71.0 0.7 71.0 0.5 8.8 70.3 114.6 8.3 65.0 3.7 2.1 9.9 11.6 5.0 5.3 11.3 46.4 68.8 71.4 11.5 0.6 38.6 2.6 71.4 70.9 2.9 3.1 8.0 1.4 105.2 72.4 9.5 1.1 2.3 1.4 6.4 14.5 2.0 4.3 11.3 68.9 0.1 3.7 1.5 73.0 1.8 5.0 30.8 1.4 4.3 4.4 69.1 0.2 0.6 0.0 0.7 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.3 0.2 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.1 0.8 0.5 0.0 0.9 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.7 0.5 0.0 0.3 0.7 0.7 0.4 0.3 0.3 0.8 0.4 1.0 0.0 0.5 0.7 0.3 0.2 0.0 0.1 0.0 0.3 0.3 0.0 0.6 0.2 0.4 0.5 0.4 1.2 0.6 0.5 1.1 0.7 1.7 0.6 0.2 1.2 1.0 0.4 0.2 0.7 0.9 1.2 0.3 0.9 0.7 0.0 0.7 0.1 0.3 0.8 0.5 71.0 71.0 70.3 114.6 68.8 71.4 71.4 70.9 72.4 68.9 73.0 69.1 88.9 0.0 0.5 0.0 0.3 3.4 0.6 0.3 0.0 0.5 1.2 2.8 11.0 0.0 1.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.7 70.2 0.0 0.0 0.7 0.0 0.2 4.4 0.0 0.3 0.0 0.0 0.7 0.1 0.8 1.7 0.6 0.0 0.0 0.0 3.9 0.6 0.3 1.6 0.0 2.8 0.0 1.0 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 762.6 9.5 209.3 0.0 0.3 0.7 2.4 0.3 0.8 32.3 0.0 0.7 HPSE2 "HPA2, HPR2, UFS" ENSG00000172987 "Heparanase 2 (inactive)" Q8WWQ2 10 98457077-99235862 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.6;cervix: 36.7;vagina: 27.6" "Cell type enriched" "Detected in some" 9 "Astrocytes: 900.7" "Cancer enhanced" "Detected in some" "prostate cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "BJ hTERT+: 10.2;HEL: 20.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044603 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA044603: AB_10794051" "unprognostic (2.44e-1)" "unprognostic (4.28e-3)" "unprognostic (4.83e-3)" "unprognostic (6.00e-2)" "unprognostic (1.15e-1)" "unprognostic (1.59e-1)" "unprognostic (3.05e-2)" "unprognostic (1.82e-2)" "unprognostic (4.03e-2)" "unprognostic (7.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-4)" "unprognostic (5.79e-2)" "unprognostic (2.51e-1)" "unprognostic (9.39e-3)" "unprognostic (6.13e-3)" 2.0 0.0 9.9 2.0 20.9 0.0 5.2 15.4 7.6 36.7 3.6 2.9 2.7 4.5 0.0 14.3 1.8 1.4 0.1 5.8 21.1 3.5 0.0 2.2 0.0 23.2 29.6 0.2 0.0 0.0 0.3 1.5 21.5 11.1 3.0 0.0 2.4 4.2 0.3 3.2 5.2 1.7 16.5 0.0 4.6 2.7 28.5 0.1 0.1 3.0 0.4 18.3 27.6 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 10.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.9 20.9 15.4 7.6 5.8 21.1 23.2 29.6 21.5 16.5 28.5 11.9 0.3 0.0 0.0 900.7 0.0 0.0 4.8 0.0 0.0 0.0 0.2 0.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.4 24.8 0.3 0.0 0.0 6.4 0.0 0.0 4.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 97.3 0.2 0.0 0.0 0.0 48.6 0.3 0.0 0.0 40.3 0.0 0.0 0.0 16.6 4.6 0.0 0.0 0.4 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.9 1.9 11.5 2.1 0.0 0.1 0.0 0.2 0.8 0.0 0.7 HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Distal enterocytes: 44.9;Glandular and luminal cells: 41.6;Suprabasal keratinocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" 5.7 3.0 5.5 3.1 6.2 0.1 3.4 1.7 6.5 5.0 2.1 8.8 2.7 4.3 4.8 3.3 7.4 7.1 1.5 6.1 5.3 4.2 0.7 4.1 1.2 4.6 2.9 5.9 0.6 0.9 0.5 3.9 3.6 2.4 5.1 0.2 1.8 3.5 0.9 5.1 4.3 5.4 3.2 1.0 1.7 0.8 5.8 1.2 1.2 2.2 1.4 14.3 5.0 4.1 2.6 6.1 0.0 0.0 2.7 28.5 4.2 4.6 15.3 13.3 8.8 1.1 21.8 0.0 13.4 10.6 13.5 17.3 0.0 6.3 17.7 10.1 0.0 1.4 9.7 0.0 8.4 4.5 2.4 10.0 3.7 30.4 10.5 18.4 19.1 0.2 0.0 0.1 5.8 0.0 0.0 1.9 0.0 2.6 5.4 0.4 1.6 0.6 23.2 3.6 0.2 0.0 6.6 4.6 0.0 0.2 0.0 3.5 28.8 14.8 9.4 15.3 23.4 0.0 1.7 0.1 22.5 3.9 13.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 5.5 6.2 1.7 6.5 6.1 5.3 4.6 2.9 3.6 3.2 5.8 4.1 11.5 6.4 1.1 33.3 0.1 46.1 8.9 7.4 6.8 0.0 0.5 0.5 0.5 0.0 19.3 1.8 0.0 0.2 0.0 44.9 0.0 0.6 0.3 20.5 6.9 20.2 3.5 0.0 34.6 0.7 1.0 16.7 8.6 41.6 2.5 28.8 2.5 0.0 27.2 0.0 19.1 15.1 4.1 12.5 12.3 0.2 3.7 9.8 0.0 2.8 0.1 0.0 0.0 2.0 1.1 14.0 21.0 0.0 0.0 6.2 29.1 0.7 5.0 0.2 0.0 6.8 2.8 1.8 3.3 2.2 41.5 0.5 1.0 0.2 15.8 19.3 HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.6;placenta: 6.7;stomach 1: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "pancreatic cancer: 0.7;stomach cancer: 0.8;testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HUVEC TERT2: 79.4;TIME: 35.1" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 11.7" HPA028808 Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Plasma membrane" "Endoplasmic reticulum" "HPA028808: AB_2672782" "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 0.8 0.6 2.1 0.4 6.0 0.0 0.2 0.0 3.8 0.8 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.5 0.0 1.2 2.1 0.5 0.0 0.4 0.0 0.6 4.3 0.3 0.1 0.0 0.2 6.7 1.2 0.2 0.1 0.3 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.0 5.0 0.5 9.6 0.0 0.2 0.3 0.0 1.3 0.5 1.4 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 3.5 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.2 0.6 2.2 1.4 79.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 6.0 0.0 3.8 1.2 2.1 0.6 4.3 1.2 0.1 9.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ID4 bHLHb27 ENSG00000172201 "Inhibitor of DNA binding 4, HLH protein" P47928 6 19837370-19842197 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 274.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 246.6;Endometrial ciliated cells: 438.4;Endometrial stromal cells: 362.6;Glandular and luminal cells: 335.3;Muller glia cells: 391.8;Smooth muscle cells: 368.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 111.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 45.0;AN3-CA: 50.7;EFO-21: 105.1;HEK 293: 66.0;SCLC-21H: 117.0;SuSa: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075639 Supported Nucleoplasm NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA075639: " "unprognostic (3.25e-3)" "unprognostic (7.37e-3)" "unprognostic (1.80e-1)" "unprognostic (6.34e-3)" "unprognostic (4.17e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-1)" "unprognostic (2.87e-1)" "unprognostic (1.65e-2)" "prognostic favorable (2.49e-4)" "unprognostic (7.26e-2)" "unprognostic (1.66e-3)" "unprognostic (2.41e-2)" "unprognostic (3.13e-2)" "unprognostic (1.03e-3)" "unprognostic (2.57e-3)" 74.6 5.0 50.1 7.5 47.6 0.2 41.7 33.6 55.4 41.0 22.8 9.8 7.2 30.0 9.4 21.7 70.3 10.2 75.7 48.0 59.6 30.8 4.4 27.8 5.0 42.8 60.8 48.4 19.1 2.5 36.4 22.2 42.2 29.7 6.7 19.4 27.1 44.0 3.6 107.8 11.9 21.0 43.6 20.2 19.8 23.0 58.5 2.0 274.7 3.1 2.1 31.4 33.1 40.2 0.0 0.6 45.0 50.7 1.2 0.1 0.1 5.8 0.1 0.4 0.0 0.0 0.0 0.0 105.1 14.1 0.2 20.3 0.0 0.0 0.4 0.0 66.0 0.0 0.0 0.5 0.3 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 8.1 6.3 0.0 0.0 0.0 0.2 7.6 14.2 117.0 1.5 0.0 1.8 7.2 37.6 3.2 0.0 0.0 0.2 5.6 0.1 1.6 0.0 0.1 1.1 1.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.1 47.6 33.6 55.4 48.0 59.6 42.8 60.8 42.2 43.6 58.5 40.2 31.8 96.1 53.0 229.9 1.9 83.1 190.8 16.7 232.8 11.2 143.8 246.6 42.5 7.2 19.6 68.0 2.1 9.9 2.9 15.6 50.9 18.0 2.1 438.4 362.6 19.9 91.6 0.0 1.8 3.3 9.5 83.9 118.3 335.3 0.0 17.6 23.9 0.0 2.7 3.3 1.2 23.4 22.4 0.6 24.8 7.9 8.1 5.3 88.9 2.8 0.0 391.8 0.0 0.5 0.3 1.4 27.1 0.0 1.4 93.6 8.2 76.0 8.4 13.7 0.0 76.3 368.8 1.2 44.9 119.6 78.6 5.9 6.1 0.7 7.8 42.4 INAFM2 "LINC00984, OGU1" ENSG00000259330 "InaF motif containing 2" P0DMQ5 15 40323692-40326715 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Early spermatids: 25.3;Hofbauer cells: 19.5;Spermatocytes: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.6" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;granulocytes: 2.6;monocytes: 1.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (6.03e-2)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" "unprognostic (5.59e-2)" "unprognostic (9.05e-2)" "unprognostic (8.01e-3)" "unprognostic (2.43e-2)" "prognostic favorable (7.87e-4)" "unprognostic (1.23e-1)" "unprognostic (1.20e-1)" "unprognostic (1.52e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (1.88e-7)" "prognostic unfavorable (5.01e-4)" "unprognostic (2.35e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" 11.3 8.4 16.1 9.9 17.9 12.7 7.6 15.5 17.1 8.5 15.2 49.9 6.7 12.2 5.8 8.1 21.3 11.0 28.8 16.4 18.4 7.9 6.7 11.5 5.8 19.3 16.9 10.0 11.5 12.2 10.4 17.6 16.9 10.8 13.4 12.6 9.4 22.5 13.6 6.5 12.9 17.3 18.2 10.7 28.2 10.2 17.0 5.2 26.9 15.0 6.2 14.4 7.8 22.2 18.7 1.8 16.8 10.7 14.2 6.9 38.6 23.0 11.5 18.0 14.8 6.9 3.7 1.6 19.8 12.6 10.6 41.7 26.3 27.1 25.1 5.5 8.8 50.4 6.9 3.9 18.3 27.0 34.3 18.2 9.8 6.7 18.8 26.5 18.7 12.9 27.6 39.6 25.4 2.7 7.9 21.5 12.3 14.5 14.1 3.9 20.2 44.8 13.2 21.3 35.9 14.2 8.2 9.7 8.3 28.6 9.4 33.1 24.5 24.8 18.4 12.6 16.8 10.2 2.7 4.8 18.4 43.5 24.1 0.6 1.0 2.6 0.1 1.1 0.1 0.3 0.1 0.0 0.5 0.0 0.0 0.1 0.7 0.1 1.0 1.1 0.2 0.6 16.1 17.9 15.5 17.1 16.4 18.4 19.3 16.9 16.9 18.2 17.0 22.2 6.4 0.0 3.7 3.9 2.3 0.0 1.2 0.0 0.0 7.8 6.8 5.5 18.0 4.3 0.6 3.7 4.2 3.3 3.1 4.3 0.0 2.3 25.3 2.2 3.8 6.0 2.4 1.7 3.4 2.6 0.6 2.4 3.6 2.3 1.3 1.8 12.1 2.7 19.5 8.4 4.5 1.4 0.0 14.1 0.0 4.6 1.2 13.8 0.0 6.5 8.0 6.7 4.1 4.0 1.4 2.3 1.9 4.9 0.4 3.2 1.4 0.8 1.5 4.8 0.0 2.4 9.8 32.4 4.4 1.1 0.0 1.4 1.7 4.9 1.5 2.4 INF2 "C14orf151, C14orf173, MGC13251" ENSG00000203485 "Inverted formin 2" Q27J81 14 104681146-104722535 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.3;Gastric mucus-secreting cells: 183.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 100.8" "Region enhanced" "Detected in all" "basal ganglia: 224.1" "Low region specificity" "Detected in all" HPA000724 Approved Approved "Nuclear bodies,Endoplasmic reticulum" NA NA 3000000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Nuclear bodies" "HPA000724: AB_1078325" "unprognostic (1.42e-1)" "unprognostic (9.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.00e-2)" "unprognostic (1.49e-2)" "unprognostic (5.90e-3)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.13e-2)" "unprognostic (9.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-2)" "unprognostic (1.36e-3)" "unprognostic (7.24e-2)" "unprognostic (4.01e-1)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.70e-2)" 42.8 21.4 14.0 8.4 29.6 7.5 35.2 18.3 29.5 28.7 1.4 40.4 21.2 24.3 2.3 20.4 20.9 8.9 24.1 14.7 14.7 27.3 30.2 34.3 6.9 30.7 25.5 13.6 15.7 2.0 8.3 11.7 27.5 23.2 4.7 3.3 17.9 7.5 13.7 26.9 31.7 4.4 12.2 31.4 34.7 32.2 26.3 2.1 20.8 1.5 3.4 30.2 28.5 71.2 26.3 92.1 9.9 16.0 7.6 12.2 84.2 49.0 14.5 21.9 14.0 35.5 40.2 3.7 46.6 17.9 17.0 43.3 9.4 22.7 9.5 18.5 26.6 22.0 59.9 23.9 16.5 6.8 21.0 11.4 14.5 15.8 6.8 15.0 24.1 9.1 10.7 10.5 18.0 30.0 10.2 17.9 17.1 18.3 100.8 29.8 19.2 9.4 12.6 38.0 20.5 12.8 26.4 36.7 11.7 8.0 8.0 4.9 49.9 29.4 22.1 45.7 22.5 6.9 3.7 3.7 41.2 12.1 25.1 0.5 2.1 0.1 0.9 0.7 0.7 1.6 3.2 0.6 2.4 1.5 2.5 1.6 1.6 1.2 0.1 5.1 4.0 3.2 14.0 29.6 18.3 29.5 14.7 14.7 30.7 25.5 27.5 12.2 26.3 71.2 48.8 64.1 13.4 10.1 22.5 22.7 17.5 19.0 17.1 0.3 16.5 14.6 14.3 28.6 15.0 3.7 0.0 54.8 5.2 229.3 5.9 24.1 1.2 7.8 8.6 29.8 17.4 17.2 16.7 25.5 87.8 17.9 183.0 18.2 14.7 8.4 25.4 29.8 32.6 0.0 1.9 86.2 12.2 21.8 35.6 2.1 5.6 25.5 8.8 20.6 14.0 55.3 1.0 11.1 89.6 58.1 110.7 4.5 7.8 26.6 90.4 7.3 9.4 2.0 32.9 5.7 36.1 1.1 4.5 8.5 18.8 31.6 9.3 12.9 66.9 38.2 IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 7.4;Hofbauer cells: 11.1;Smooth muscle cells: 28.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cell line enhanced" "Detected in some" "ASC diff: 20.8;BJ: 15.3;BJ hTERT+: 17.6;fHDF/TERT166: 6.9;REH: 6.8" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" 29.7 8.0 64.6 18.2 85.8 1.5 16.1 50.4 53.4 55.4 17.7 67.6 8.5 60.8 16.1 37.5 45.6 33.2 10.1 54.5 54.3 9.3 2.1 13.3 3.7 65.8 71.4 20.2 2.9 2.7 3.8 11.8 54.4 37.9 17.3 1.7 4.1 39.5 6.7 9.3 22.0 69.1 55.2 7.1 33.7 8.2 89.8 2.3 10.2 8.1 1.8 43.8 21.9 48.8 0.1 0.0 4.2 0.0 20.8 4.1 0.2 15.3 17.6 0.0 0.0 0.4 1.7 0.0 0.1 6.9 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.7 0.0 0.1 0.2 0.0 0.2 4.8 0.4 0.0 0.1 0.0 1.2 0.0 0.6 0.1 0.3 0.0 0.1 0.3 0.5 0.0 0.1 6.8 0.0 0.3 0.0 0.0 0.0 3.1 0.0 2.6 0.0 4.4 0.0 0.5 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 6.0 0.0 0.7 2.2 1.7 0.0 3.9 0.0 0.8 0.0 0.0 0.6 0.9 0.0 0.0 24.0 0.0 5.7 0.1 0.0 0.7 64.6 85.8 50.4 53.4 54.5 54.3 65.8 71.4 54.4 55.2 89.8 48.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 ITGAV "CD51, MSK8, VNRA, VTNR" ENSG00000138448 "Integrin subunit alpha V" P06756 2 186590056-186680901 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "RT4: 369.7;SuSa: 297.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002499, HPA004856" Supported Approved "Focal adhesion sites,Cytosol" NA NA 2000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites, Cytosol" "CAB002499: AB_563594, HPA004856: AB_1846316" "unprognostic (4.03e-2)" "unprognostic (5.17e-3)" "unprognostic (1.22e-2)" "unprognostic (5.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.48e-2)" "unprognostic (6.95e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (5.84e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.61e-1)" "unprognostic (9.11e-2)" "unprognostic (8.07e-2)" 39.9 38.7 20.1 36.5 30.8 6.4 27.7 39.7 23.5 39.7 40.3 20.1 15.9 36.8 10.5 24.5 26.3 47.3 80.0 18.2 32.7 52.1 18.0 25.7 15.8 42.5 33.0 64.7 25.7 82.7 11.9 47.4 46.4 29.8 21.6 80.4 32.1 28.1 16.3 41.4 16.3 56.7 45.3 21.4 34.2 14.7 30.2 18.0 62.6 30.5 21.6 43.1 16.0 54.6 49.1 57.5 37.4 119.9 134.1 90.0 141.7 93.8 75.5 32.5 32.5 50.7 164.0 0.4 179.7 106.3 113.4 60.2 19.3 88.5 46.7 9.7 17.2 11.7 69.1 69.6 52.8 8.3 7.0 65.8 41.3 72.7 61.1 194.1 78.7 5.9 11.6 23.9 87.4 19.4 5.0 6.8 28.3 29.1 28.5 0.1 76.2 6.8 83.5 369.7 7.7 23.0 108.6 33.2 40.1 297.0 26.2 22.4 240.5 199.4 61.9 41.4 80.3 5.9 10.4 5.5 80.3 3.3 100.6 6.2 0.6 0.9 0.4 1.1 0.3 0.1 0.2 0.4 0.4 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.6 0.2 20.1 30.8 39.7 23.5 18.2 32.7 42.5 33.0 46.4 45.3 30.2 54.6 39.8 28.9 22.9 134.8 4.9 128.4 64.0 127.7 42.7 118.4 50.4 23.4 145.5 80.1 35.3 77.3 77.2 55.1 9.4 32.4 1.9 78.7 0.6 61.7 61.1 47.2 7.3 2.1 36.3 101.8 26.9 65.4 57.6 100.2 49.5 21.2 27.8 18.2 27.6 15.2 35.9 19.9 14.2 44.3 56.7 3.1 19.3 29.3 46.2 75.9 17.4 70.9 2.1 184.5 156.1 165.9 23.8 25.9 9.2 103.4 11.2 32.4 27.0 60.2 32.9 29.0 63.3 1.7 2.4 27.7 103.7 39.7 10.9 18.1 15.5 77.7 ITGB1BP1 "ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B" ENSG00000119185 "Integrin subunit beta 1 binding protein 1" O14713 2 9403475-9423528 "Predicted intracellular proteins" "Angiogenesis, Biomineralization, Cell adhesion, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 391.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067348, HPA071538" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA067348: AB_2732765, HPA071538: AB_2686413" "unprognostic (2.21e-1)" "unprognostic (8.31e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.39e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (4.67e-5)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (6.46e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (7.10e-5)" "unprognostic (3.75e-2)" "unprognostic (2.01e-1)" "unprognostic (1.14e-3)" "unprognostic (4.08e-3)" 113.7 23.2 45.5 19.3 63.1 31.3 60.4 50.3 58.0 43.7 49.3 37.3 13.6 31.0 26.6 20.9 24.3 22.6 37.3 46.4 48.3 50.2 13.3 22.8 22.1 48.2 47.0 22.3 11.8 26.2 19.1 24.2 49.9 18.5 24.2 27.5 15.5 23.7 29.8 29.7 19.1 35.9 41.8 15.2 22.9 9.4 54.3 27.0 22.4 33.5 25.7 30.4 32.5 52.7 53.5 35.4 43.4 51.5 148.9 131.2 23.3 94.9 66.2 83.8 66.1 49.5 33.1 55.6 43.1 135.9 56.1 50.1 66.3 62.7 92.8 158.6 30.2 53.2 43.2 61.1 54.1 42.2 57.4 70.5 49.5 78.4 56.5 75.2 76.6 43.0 29.9 46.1 109.0 44.6 74.7 25.5 35.9 90.3 53.9 39.4 59.1 51.4 88.5 40.6 44.1 45.0 54.8 40.3 71.3 38.9 30.5 32.1 48.6 73.8 54.5 103.3 105.7 46.8 111.0 89.0 106.1 54.8 54.5 86.1 43.1 56.0 54.9 54.0 52.5 40.1 46.6 53.2 56.8 33.0 35.2 45.7 9.3 50.4 41.1 52.8 61.7 53.1 45.5 63.1 50.3 58.0 46.4 48.3 48.2 47.0 49.9 41.8 54.3 52.7 90.0 28.9 18.1 18.3 47.1 61.2 40.6 70.4 40.9 25.2 30.4 41.8 104.3 22.8 35.1 38.6 2.1 45.0 70.7 16.1 391.3 72.0 26.3 31.3 51.9 85.5 33.1 49.4 61.6 72.7 73.9 98.6 25.5 30.9 41.7 44.4 53.6 21.6 91.4 35.3 47.3 30.4 32.6 45.0 88.5 25.7 54.3 51.7 97.8 15.9 95.6 64.2 121.5 25.6 40.1 108.9 27.0 57.2 42.7 35.2 24.7 88.4 35.6 30.6 92.1 49.0 102.4 27.8 19.0 47.5 63.1 31.5 63.0 70.7 35.2 60.4 ITM2C "BRI3, BRICD2C, E25, hRPC.1050_D_4, ITM3" ENSG00000135916 "Integral membrane protein 2C" Q9NQX7 2 230864639-230879248 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.2;intestine: 707.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2610.8;Intestinal goblet cells: 884.1;Paneth cells: 2076.6;Plasma cells: 1010.4;Undifferentiated cells: 843.5" "Cancer enhanced" "Detected in all" "glioma: 496.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 2464.2" "Lineage enriched" "Detected in all" 8 "dendritic cells: 2464.2" "Cell line enhanced" "Detected in many" "EFO-21: 517.7;NB-4: 599.8;RPMI-8226: 482.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 29000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.50e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (3.74e-1)" "unprognostic (6.03e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (4.44e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-2)" "unprognostic (1.04e-1)" "unprognostic (2.08e-1)" "unprognostic (4.92e-2)" "unprognostic (1.93e-1)" "unprognostic (2.70e-2)" "unprognostic (2.52e-2)" 42.5 89.0 861.0 116.0 900.6 109.6 31.4 710.8 1106.2 116.8 553.9 707.6 80.2 103.5 40.0 84.4 58.6 54.0 57.4 854.3 996.3 177.3 36.7 45.3 78.2 928.0 960.3 78.1 80.3 105.5 288.4 108.8 800.9 103.4 539.0 118.3 72.3 110.2 22.4 20.4 329.3 95.3 909.4 117.5 87.5 22.1 1082.7 178.6 52.9 33.8 72.1 124.2 74.9 840.3 34.1 67.0 215.6 170.6 27.2 15.3 68.8 176.0 191.6 92.5 144.2 89.7 46.8 0.4 517.7 126.3 94.9 16.8 127.2 25.6 58.1 328.3 109.0 44.7 33.6 119.1 96.0 81.1 180.9 131.4 24.7 83.6 8.2 33.8 3.5 76.8 43.6 108.3 35.5 53.0 59.3 599.8 263.5 184.0 58.8 85.2 37.0 482.9 123.5 200.8 11.8 329.4 85.8 10.3 207.4 220.7 17.0 455.6 2.9 39.6 114.4 70.5 50.0 0.7 9.1 4.6 124.6 70.1 336.5 76.5 3.6 291.0 12.5 1.8 33.2 185.2 39.7 33.1 68.9 94.7 38.1 31.6 6.9 52.0 0.6 2464.2 64.2 50.0 861.0 900.6 710.8 1106.2 854.3 996.3 928.0 960.3 800.9 909.4 1082.7 840.3 26.3 6.4 10.8 155.7 167.8 24.1 49.7 9.3 29.0 428.1 24.4 40.0 20.5 61.5 16.5 138.0 252.3 95.7 483.6 2610.8 27.4 123.0 0.8 43.0 34.0 36.2 408.3 8.4 49.3 39.5 63.4 94.9 21.4 45.6 183.9 41.6 16.4 14.8 80.1 101.0 63.3 884.1 12.2 7.5 108.9 3.4 54.3 26.0 202.7 27.2 70.9 225.9 3.1 107.5 17.8 46.2 2076.6 69.2 1010.4 52.9 666.0 23.7 16.5 101.1 138.1 30.9 108.6 4.8 20.5 3.8 14.9 57.6 75.3 37.9 843.5 97.7 ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 106.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.9" "Group enriched" "Detected in all" 5 "granulocytes: 42.9;monocytes: 25.9" "Cell line enhanced" "Detected in all" "WM-115: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA055230: AB_2682748" "unprognostic (1.93e-3)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "prognostic favorable (8.56e-4)" "unprognostic (4.27e-1)" "unprognostic (2.04e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.24e-2)" "unprognostic (2.86e-2)" "unprognostic (8.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-3)" "unprognostic (2.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.20e-1)" "unprognostic (7.25e-3)" 60.0 27.2 88.3 15.5 105.9 17.3 45.3 84.7 92.7 57.0 57.2 60.1 44.4 66.8 11.6 24.8 30.3 19.4 59.2 92.5 80.7 35.6 48.3 31.6 9.0 90.2 95.8 27.1 30.7 14.8 20.6 6.8 83.0 38.8 16.4 9.3 21.0 21.7 40.9 22.2 58.5 23.4 83.2 38.1 34.2 29.5 100.4 6.9 25.4 16.1 6.6 62.5 35.0 100.7 28.1 56.6 10.3 26.3 22.5 12.6 27.8 11.8 17.5 22.9 13.8 32.8 48.9 17.7 57.4 18.6 8.7 32.5 29.6 50.3 7.2 65.9 13.1 39.2 14.6 28.5 16.8 17.9 41.5 8.2 29.5 11.6 26.3 9.9 22.8 18.0 21.9 19.8 11.3 74.6 15.5 25.5 22.0 36.4 25.5 29.1 15.1 26.3 15.5 46.3 28.0 35.5 29.6 59.0 49.5 7.8 79.5 21.7 18.0 15.9 17.3 27.0 18.9 19.3 19.1 11.4 14.6 13.8 110.8 5.3 9.8 18.2 3.2 15.4 1.9 3.3 2.0 2.1 7.0 1.0 1.2 2.2 42.9 2.4 25.9 3.5 3.0 5.1 88.3 105.9 84.7 92.7 92.5 80.7 90.2 95.8 83.0 83.2 100.4 100.7 11.8 12.8 11.1 32.0 10.8 7.4 7.5 8.3 2.8 10.2 11.8 7.6 24.3 17.2 5.1 29.5 18.8 9.7 12.9 73.5 13.7 19.2 12.7 18.1 12.5 12.4 28.8 5.9 45.1 27.3 10.0 8.9 13.3 21.2 16.5 9.2 13.9 31.3 19.4 6.7 21.6 24.8 4.1 44.7 11.8 30.3 14.9 30.5 26.6 16.9 23.2 17.2 18.6 31.7 46.5 44.6 38.7 48.2 13.2 15.2 106.6 23.0 3.3 13.7 19.7 7.4 17.8 4.3 14.3 7.0 4.4 6.8 12.7 10.3 34.5 11.0 JAM2 "C21orf43, CD322, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Astrocytes: 81.6;Endothelial cells: 148.7;Hepatic stellate cells: 112.8;Microglial cells: 82.4;Oligodendrocyte precursor cells: 76.9" "Cancer enriched" "Detected in all" 9 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.5;BJ hTERT+: 16.5;HDLM-2: 16.7;hTERT-RPE1: 22.5;U-138 MG: 18.1;U-87 MG: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA028789: AB_2732443, HPA077346: AB_2732341" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.51e-4)" "unprognostic (2.61e-2)" "unprognostic (4.55e-1)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.81e-1)" "unprognostic (8.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.85e-3)" 20.5 15.8 16.6 3.7 21.5 0.3 16.8 24.0 21.8 16.8 12.8 17.8 6.1 18.5 11.2 7.1 16.1 12.9 19.2 19.2 22.0 9.2 2.2 15.5 3.6 25.9 23.1 16.1 2.8 4.3 8.1 63.5 21.3 9.4 7.9 7.1 6.1 15.4 7.8 5.5 10.7 19.6 26.8 1.6 10.2 17.6 25.2 2.6 10.3 13.2 5.0 11.6 13.2 23.0 0.0 0.0 25.5 0.1 1.0 0.2 0.5 0.8 16.5 2.0 7.6 0.0 0.0 0.1 0.0 0.2 9.7 0.1 2.2 0.0 4.6 16.7 0.7 0.1 0.1 0.1 0.0 0.1 0.1 1.4 0.0 1.8 0.1 22.5 0.0 0.6 0.0 0.2 8.0 0.0 0.4 0.1 8.1 0.2 0.0 3.2 5.3 0.1 0.0 0.0 0.4 3.7 0.2 0.3 0.0 0.3 0.9 0.2 0.0 18.1 1.7 0.1 2.5 1.8 0.1 0.0 13.4 0.1 0.7 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.4 0.6 0.1 0.4 0.0 0.1 16.6 21.5 24.0 21.8 19.2 22.0 25.9 23.1 21.3 26.8 25.2 23.0 173.8 0.0 2.3 81.6 0.9 7.5 1.4 0.0 2.2 1.4 1.4 9.1 33.2 0.0 0.0 3.7 14.6 0.3 0.5 0.0 0.0 0.2 16.5 1.0 4.7 148.7 0.0 0.0 15.2 0.2 5.3 28.5 0.5 2.1 0.0 4.5 112.8 0.5 1.3 0.0 45.0 0.0 0.0 1.8 10.7 15.6 9.9 2.8 16.0 82.4 0.0 1.8 0.0 76.9 4.1 0.1 0.0 24.5 1.2 1.5 0.0 0.0 0.7 5.2 0.0 5.7 7.0 6.7 4.4 0.8 6.7 0.8 1.6 2.1 0.0 1.2 JAM3 "JAM-C, JAMC" ENSG00000166086 "Junctional adhesion molecule 3" Q9BX67 11 134069071-134152001 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 342.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.3" "Group enriched" "Detected in many" 7 "B-cells: 5.3;T-cells: 2.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;RH-30: 122.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003417, HPA050434" Approved Enhanced "Golgi apparatus" "Secreted to blood" NA NA 44000 "Cluster 43: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "HPA003417: AB_1851981, HPA050434: AB_2681126" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (3.24e-1)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.59e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (5.06e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.23e-3)" "unprognostic (2.17e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.68e-4)" 23.6 18.7 53.4 10.1 86.3 1.3 19.2 68.7 73.4 33.4 52.9 54.6 6.6 40.8 17.5 21.5 28.7 24.5 31.0 56.5 61.3 11.4 3.2 29.6 7.8 73.5 76.8 48.7 5.1 17.7 33.3 102.7 71.0 32.5 12.9 47.3 13.3 44.5 7.0 13.0 22.5 42.8 59.7 13.5 22.4 35.7 73.3 17.6 15.8 14.6 7.5 41.7 23.4 115.2 0.0 1.0 87.9 42.5 85.3 62.7 75.4 37.0 49.1 15.1 14.8 0.3 0.6 0.0 38.7 53.3 56.2 0.5 70.0 0.7 28.2 0.2 29.6 0.3 0.0 6.9 24.9 0.4 36.2 43.2 0.0 10.7 9.6 35.8 99.5 40.8 0.3 0.2 64.5 1.0 27.5 0.2 18.9 0.6 2.9 0.5 122.8 0.0 0.9 0.2 57.5 32.2 0.0 0.2 1.0 35.3 0.2 0.2 0.6 25.1 18.4 40.3 24.7 0.1 0.1 0.4 27.6 1.2 48.0 0.0 0.0 0.1 1.3 0.0 1.6 5.3 1.6 0.9 0.0 3.1 2.3 1.7 0.5 0.0 0.0 0.0 0.0 1.8 53.4 86.3 68.7 73.4 56.5 61.3 73.5 76.8 71.0 59.7 73.3 115.2 22.2 0.0 6.0 12.7 10.9 5.1 5.6 0.9 0.0 21.7 0.3 9.3 15.7 0.0 0.7 5.5 8.4 6.0 1.2 0.1 1.9 0.4 2.1 0.8 23.3 35.5 0.0 0.4 84.3 0.2 71.2 29.6 1.5 0.5 1.3 11.7 12.5 0.0 8.6 8.4 44.2 0.0 12.2 0.6 4.2 4.9 42.9 10.9 17.8 24.4 0.2 20.2 1.0 76.4 342.8 0.3 0.0 64.3 0.9 2.2 0.0 0.2 1.5 75.6 26.3 19.0 24.3 15.5 19.2 0.2 3.8 6.2 3.5 9.7 0.0 1.0 KCNG1 "K13, KCNG, kH2, Kv6.1" ENSG00000026559 "Potassium voltage-gated channel modifier subfamily G member 1" Q9UIX4 20 51003656-51023107 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.8;endometrium 1: 87.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.7;Granulosa cells: 34.0;Syncytiotrophoblasts: 97.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 8.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "naive B-cell: 7.1" "Lineage enriched" "Detected in single" 71 "B-cells: 7.1" "Cell line enhanced" "Detected in many" "hTCEpi: 53.5;U-138 MG: 40.4;WM-115: 34.6" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 19.1;cerebral cortex: 14.9;hippocampal formation: 18.1;white matter: 9.1" "Group enriched" "Detected in all" 5 "amygdala: 12.6;basal ganglia: 11.1;cerebral cortex: 22.4;hippocampal formation: 16.8" "HPA039530, HPA040024" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA039530: AB_10795144, HPA040024: AB_10796338" "unprognostic (1.19e-1)" "unprognostic (4.47e-2)" "unprognostic (8.70e-2)" "unprognostic (3.49e-2)" "unprognostic (4.07e-2)" "unprognostic (5.05e-4)" "unprognostic (2.53e-2)" "unprognostic (3.89e-3)" "unprognostic (3.64e-2)" "unprognostic (3.43e-2)" "unprognostic (8.74e-2)" "unprognostic (8.89e-2)" "unprognostic (1.83e-9)" "unprognostic (1.52e-1)" "unprognostic (7.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" 0.4 3.0 17.3 2.2 26.7 0.0 0.4 0.0 21.7 17.9 0.1 5.0 0.2 87.4 0.8 6.7 19.2 0.9 1.3 14.9 0.6 0.5 0.2 0.3 2.2 28.9 46.8 0.7 2.7 4.1 0.8 7.1 3.2 5.6 0.8 0.1 2.2 12.8 0.0 0.5 5.3 4.1 1.0 2.7 0.7 9.5 1.2 0.2 0.2 0.0 0.9 3.4 6.2 1.1 0.9 3.6 2.7 13.3 1.5 3.4 0.2 11.6 0.1 6.7 5.3 0.2 0.2 0.0 7.1 3.5 18.8 3.4 1.7 3.5 6.9 0.4 4.7 0.0 13.6 0.0 23.2 0.0 0.4 6.8 53.5 25.7 26.1 1.3 1.8 0.1 0.2 0.0 0.6 13.4 0.0 0.4 13.7 0.0 25.0 0.0 0.0 0.0 0.0 4.1 3.9 15.0 25.5 29.3 19.9 4.3 2.1 1.9 0.7 40.4 23.9 0.3 3.4 0.1 0.0 0.0 11.8 1.0 34.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.3 26.7 0.0 21.7 14.9 0.6 28.9 46.8 3.2 1.0 1.2 1.1 0.2 3.2 1.1 0.3 10.5 1.1 11.0 0.6 13.6 0.3 1.1 2.3 1.1 7.2 0.9 0.0 0.0 53.7 0.0 7.5 0.0 2.6 18.2 9.3 2.0 1.2 0.0 0.0 2.0 0.0 2.7 1.5 0.5 15.9 0.0 34.0 0.4 0.3 3.3 1.7 2.2 0.6 0.0 0.0 0.3 20.3 1.5 0.3 0.0 1.0 0.0 0.2 1.0 0.0 0.6 0.2 3.4 4.1 0.0 18.1 12.8 0.1 0.9 0.2 0.0 1.1 7.1 12.7 0.7 5.4 0.3 97.0 0.4 0.3 0.4 9.9 LARP6 "acheron, FLJ11196" ENSG00000166173 "La ribonucleoprotein 6, translational regulator" Q9BRS8 15 70829130-70854157 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 429.0;Late spermatids: 259.8;Spermatocytes: 166.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 232.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020338, HPA049029" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Microtubules "Cytokinetic bridge" "HPA020338: AB_1844500, HPA049029: AB_2680604" "unprognostic (1.35e-3)" "unprognostic (1.95e-1)" "unprognostic (7.43e-2)" "unprognostic (2.63e-3)" "unprognostic (2.96e-2)" "unprognostic (4.70e-2)" "unprognostic (2.44e-2)" "unprognostic (2.80e-3)" "unprognostic (4.27e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (9.90e-5)" "unprognostic (4.51e-3)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" "unprognostic (3.43e-1)" 51.4 9.8 42.8 6.5 69.8 0.1 44.0 56.9 65.5 27.5 22.8 18.5 2.1 22.8 28.4 7.9 29.0 10.9 43.4 44.5 52.0 27.9 10.6 17.9 2.3 57.8 56.6 30.4 10.9 19.6 23.6 7.7 56.4 26.1 4.0 11.8 19.5 14.1 17.6 14.0 10.3 12.1 46.8 2.6 26.9 9.6 55.9 5.1 40.8 26.1 1.5 21.1 31.0 90.4 42.3 44.2 14.1 28.3 70.2 77.9 0.1 127.7 99.0 67.4 71.2 12.9 12.0 0.0 50.9 69.9 65.4 22.7 32.0 11.2 66.4 0.4 78.3 0.2 37.6 12.0 127.1 0.2 0.2 49.0 45.6 67.9 107.5 70.6 22.2 15.4 0.1 0.6 30.4 7.3 0.3 0.3 14.9 0.0 113.9 0.2 50.6 0.3 22.0 35.9 8.4 18.5 42.5 0.5 93.1 21.7 2.3 2.4 29.6 27.4 109.6 232.0 107.5 0.2 0.3 0.4 116.9 0.0 14.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 42.8 69.8 56.9 65.5 44.5 52.0 57.8 56.6 56.4 46.8 55.9 90.4 32.3 0.0 1.1 2.9 0.1 18.1 47.7 20.4 9.6 41.4 15.4 18.3 22.2 24.3 11.8 12.9 2.1 0.5 1.0 0.3 54.8 59.4 429.0 24.6 31.8 24.5 12.0 0.0 10.8 25.1 0.8 87.5 4.1 8.4 0.0 7.5 11.4 15.3 1.2 25.2 11.8 1.5 10.2 0.6 13.3 259.8 73.3 3.2 19.6 7.5 0.1 28.5 0.0 5.5 105.9 62.9 0.0 45.9 0.5 61.9 0.0 100.9 16.8 4.8 19.7 28.3 34.8 166.8 11.0 1.4 8.9 0.4 1.9 5.3 0.6 37.7 LAYN "FLJ30977, FLJ31092" ENSG00000204381 Layilin Q6UX15 11 111540280-111561745 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 233.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "myeloid DC: 11.2;T-reg: 13.4" "Group enriched" "Detected in many" 123 "dendritic cells: 11.2;T-cells: 13.4" "Cell line enhanced" "Detected in many" "BJ: 150.7;BJ hTERT+: 153.7;BJ hTERT+ SV40 Large T+ RasG12V: 96.7;fHDF/TERT166: 95.1;HSkMC: 88.8;hTERT-RPE1: 94.0;U-138 MG: 108.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040087 Approved Approved Cytosol NA NA 340000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA040087: AB_10793927" "unprognostic (2.27e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-3)" "unprognostic (1.96e-1)" "unprognostic (3.90e-2)" "unprognostic (1.83e-2)" "unprognostic (5.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-1)" "unprognostic (7.75e-3)" "unprognostic (4.47e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-2)" "unprognostic (1.35e-2)" 10.7 2.0 15.6 5.7 21.4 1.0 8.5 15.7 19.6 15.6 13.7 29.2 3.8 15.8 10.1 4.7 17.7 17.0 7.0 16.6 17.1 5.7 0.9 11.3 7.1 17.4 19.7 39.1 2.0 6.4 6.2 14.1 16.3 14.6 3.3 0.8 5.5 17.0 6.1 2.6 10.6 22.5 14.2 8.2 13.1 4.4 18.0 10.3 27.4 6.1 5.0 8.8 12.2 23.7 0.4 3.9 0.8 0.0 25.4 48.0 7.6 150.7 153.7 71.0 96.7 0.2 0.1 0.0 1.4 95.1 18.7 3.2 9.9 0.7 74.2 0.2 0.5 0.8 0.0 0.2 41.7 0.0 0.2 88.8 0.0 30.8 0.2 94.0 0.9 0.0 0.0 0.1 29.4 0.0 0.1 0.1 4.8 0.0 0.0 0.0 11.4 0.2 0.6 0.0 4.9 18.9 0.5 0.2 0.4 34.9 0.1 0.7 0.6 108.8 81.2 1.0 74.3 0.0 0.0 0.2 14.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 11.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 13.4 0.4 15.6 21.4 15.7 19.6 16.6 17.1 17.4 19.7 16.3 14.2 18.0 23.7 22.2 19.2 2.8 0.3 0.3 2.2 48.8 44.8 0.6 0.4 0.7 15.0 2.7 2.8 23.3 0.0 0.0 1.6 2.6 0.0 0.0 6.5 2.5 3.9 7.7 50.9 0.0 2.7 0.3 0.2 2.1 13.1 0.0 0.9 1.3 9.6 6.8 0.1 0.7 0.0 1.4 0.0 6.1 0.6 13.6 1.8 22.7 1.2 0.0 2.8 0.6 0.2 0.0 4.0 30.1 0.8 0.0 55.3 2.8 233.0 0.0 0.2 32.0 0.2 32.9 2.6 17.3 0.1 2.3 0.1 2.3 0.5 14.5 11.2 0.0 50.3 LGI4 ENSG00000153902 "Leucine rich repeat LGI family member 4" Q8N135 19 35124513-35142451 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.7;Distal enterocytes: 33.1;Muller glia cells: 95.5;Sertoli cells: 78.9;Smooth muscle cells: 104.4" "Group enriched" "Detected in many" 6 "glioma: 4.5;melanoma: 11.5;renal cancer: 13.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 27 "WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042116, HPA043556" Approved Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA042116: AB_2677855, HPA043556: AB_2678550" "unprognostic (3.79e-1)" "unprognostic (6.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-2)" "unprognostic (3.71e-2)" "unprognostic (2.12e-2)" "unprognostic (4.26e-2)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.71e-2)" "unprognostic (4.47e-1)" "unprognostic (7.73e-2)" "unprognostic (7.13e-2)" 77.6 5.4 71.2 4.1 72.3 0.2 36.1 70.3 98.4 99.9 52.1 100.5 3.6 35.5 2.3 15.0 43.7 5.0 39.4 67.8 61.3 4.7 8.0 14.3 2.1 86.5 68.4 13.3 6.4 1.4 4.4 3.6 70.1 37.2 3.7 7.2 12.2 13.3 39.1 21.2 35.1 4.8 72.8 1.9 27.0 2.7 72.0 0.5 19.1 5.4 0.5 33.5 79.3 81.4 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 71.2 72.3 70.3 98.4 67.8 61.3 86.5 68.4 70.1 72.8 72.0 81.4 13.3 0.0 0.0 74.7 0.2 2.5 0.6 0.3 3.4 0.8 1.5 1.5 17.1 0.0 0.8 1.8 2.1 0.0 0.2 33.1 0.0 0.0 0.1 0.2 2.8 5.4 1.8 0.0 21.9 0.0 0.3 12.7 0.0 0.2 0.0 0.0 7.9 2.0 0.1 0.0 2.2 0.9 0.0 0.0 4.6 0.3 14.6 0.7 10.6 5.6 0.1 95.5 0.0 2.0 9.2 0.1 21.8 7.2 0.3 1.2 1.1 0.1 0.9 3.1 78.9 7.9 104.4 2.8 2.8 0.8 2.4 0.0 0.7 0.0 0.7 1.1 LIFR CD118 ENSG00000113594 "LIF receptor subunit alpha" P42702 5 38474668-38608354 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 318.9;Astrocytes: 376.8;Endothelial cells: 279.5;Hepatic stellate cells: 809.2;Oligodendrocytes: 275.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 88.0;HHSteC: 38.7;SCLC-21H: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 260000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.00e-3)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" "prognostic favorable (1.92e-4)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (2.73e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-1)" 50.0 18.1 38.8 6.2 55.1 0.1 41.7 43.6 24.8 33.5 3.0 10.2 5.8 33.0 16.5 12.1 30.9 12.4 19.9 23.4 43.9 23.9 30.9 23.8 21.0 42.7 55.2 18.6 22.3 13.4 5.0 35.9 50.2 28.9 8.8 17.4 34.1 16.8 23.4 9.7 11.0 33.4 39.6 29.9 21.9 10.0 54.1 21.3 38.5 42.8 10.2 11.7 14.5 47.5 1.3 4.3 88.0 6.8 25.4 27.0 0.6 6.7 3.8 4.7 2.9 0.9 4.6 0.0 1.2 10.1 12.4 0.7 5.5 2.1 9.0 0.0 7.0 0.0 8.7 3.7 38.7 0.0 0.5 23.5 1.6 12.0 1.5 6.1 8.6 0.9 2.3 12.3 7.3 1.3 0.0 0.2 2.1 0.0 14.8 0.1 18.4 0.0 6.0 2.0 56.6 7.2 28.3 1.6 0.0 11.7 1.9 0.0 1.5 9.0 15.7 21.0 4.3 0.0 0.0 0.0 15.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 55.1 43.6 24.8 23.4 43.9 42.7 55.2 50.2 39.6 54.1 47.5 318.9 12.8 39.7 376.8 2.6 23.2 6.3 1.2 10.8 6.4 16.8 22.1 33.1 8.6 7.3 14.7 8.4 12.1 0.6 0.0 5.9 2.0 15.0 11.0 12.4 279.5 0.0 13.5 33.7 9.3 28.0 62.9 14.3 16.9 1.3 29.6 809.2 11.8 3.5 1.7 54.2 0.0 6.1 50.3 17.7 29.7 113.7 2.3 17.8 45.0 0.0 6.2 0.0 111.6 275.5 7.0 0.0 19.9 0.0 18.5 0.0 12.3 8.3 37.3 39.5 65.9 30.8 9.6 7.3 2.0 18.2 28.6 3.7 15.8 0.0 5.5 LINC00672 ENSG00000263874 "Long intergenic non-protein coding RNA 672" 17 38925168-38929384 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 10.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 42.7;granulocytes: 35.0;Horizontal cells: 30.3;NK-cells: 37.0" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 6.3" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.28e-1)" "unprognostic (9.28e-2)" "unprognostic (6.62e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.15e-2)" "unprognostic (8.81e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.68e-6)" "unprognostic (7.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.44e-2)" "unprognostic (2.59e-4)" 1.2 1.9 9.4 1.0 9.5 3.1 0.9 7.3 10.8 1.0 4.5 1.5 0.9 2.0 2.3 0.8 2.2 1.4 1.0 9.5 10.3 0.6 0.6 1.5 1.3 8.7 9.6 2.0 1.0 0.1 1.9 0.9 9.6 1.3 1.4 3.8 0.8 2.3 0.7 1.8 2.5 1.8 7.0 2.3 1.7 0.5 9.0 0.8 0.5 0.3 0.8 1.2 1.1 9.7 0.4 0.5 1.1 0.7 0.5 0.7 0.2 0.4 0.3 0.1 0.3 0.2 2.1 0.3 0.4 0.6 0.0 1.1 0.0 0.2 0.3 0.2 0.3 0.4 0.6 0.0 0.2 0.8 1.4 0.8 0.4 0.3 0.1 0.8 0.1 0.6 0.1 0.3 0.2 0.4 0.4 0.8 6.3 0.3 0.0 1.8 0.1 0.5 0.6 0.5 0.1 2.4 0.6 0.7 0.4 0.5 0.8 0.7 1.2 0.2 0.4 0.4 0.2 0.6 0.9 0.4 0.5 0.6 0.2 0.4 0.2 0.5 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.6 0.9 0.3 0.1 0.2 0.1 0.1 9.4 9.5 7.3 10.8 9.5 10.3 8.7 9.6 9.6 7.0 9.0 9.7 7.5 12.8 3.4 0.3 3.9 1.1 1.9 1.5 0.0 42.7 6.6 10.3 2.7 2.8 2.4 0.0 2.1 0.3 15.7 2.7 0.0 2.0 0.6 3.5 4.2 4.8 1.8 2.7 14.4 1.4 0.8 6.7 7.7 9.8 35.0 1.8 4.6 0.7 1.5 30.3 13.3 3.8 6.1 3.1 3.4 0.4 3.7 3.5 3.6 3.7 7.4 9.3 37.0 8.0 6.1 3.3 4.8 4.1 3.3 2.7 3.9 0.3 4.4 8.0 0.0 9.5 7.0 0.1 0.4 0.9 0.6 0.3 9.3 1.7 4.1 1.9 LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78757094 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;ovary: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Fibroblasts: 4.2;Leydig cells: 20.2;Oligodendrocyte precursor cells: 3.5;Skeletal myocytes: 3.6" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 6.3" "Lineage enriched" "Detected in single" 19 "granulocytes: 6.3" "Cell line enhanced" "Detected in some" "AF22: 9.3;NTERA-2: 15.2;RH-30: 6.4;U-937: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" 0.5 0.0 1.8 0.4 1.3 0.3 0.8 1.1 1.7 0.6 1.1 0.3 0.0 1.1 0.3 0.6 0.3 0.8 0.7 3.0 1.2 0.1 0.1 0.1 0.0 1.8 1.7 3.6 0.4 0.0 0.1 0.0 1.3 0.2 0.4 0.1 0.3 0.1 0.0 0.5 0.3 0.5 2.6 0.1 0.4 0.3 1.1 0.7 0.1 0.3 0.4 0.3 0.2 3.8 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.6 1.0 1.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 2.1 0.0 0.4 1.7 15.2 0.0 0.2 0.8 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 2.6 0.0 0.0 0.2 0.0 0.6 1.2 0.0 0.7 0.7 3.7 1.5 6.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 1.3 1.1 1.7 3.0 1.2 1.8 1.7 1.3 2.6 1.1 3.8 1.2 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.5 20.2 0.1 1.8 1.0 0.6 1.0 0.0 3.5 0.1 0.0 0.0 2.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 3.6 0.4 0.0 0.3 1.5 0.4 0.0 0.4 0.2 0.0 0.2 LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358633-34367196 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 85.2;Gastric mucus-secreting cells: 131.5;Urothelial cells: 129.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 108.5;OE19: 113.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA057321: " "unprognostic (2.79e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (4.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.15e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-3)" 19.7 6.2 18.0 12.2 18.3 6.7 17.8 12.8 38.5 21.6 4.0 44.8 30.9 14.4 9.4 36.1 18.7 17.0 26.0 18.8 21.2 9.3 3.4 10.0 9.7 26.2 12.8 11.8 10.2 7.1 11.8 5.1 26.0 11.1 35.9 4.9 11.8 8.8 8.3 18.6 31.2 16.7 8.5 16.3 39.7 3.3 18.1 8.7 8.4 8.0 11.2 22.2 28.9 21.6 13.7 31.9 15.7 12.6 41.4 41.9 7.5 18.8 31.5 17.6 24.0 11.6 36.0 12.4 38.4 26.3 41.3 108.5 13.8 35.5 7.8 25.2 8.2 12.5 13.6 11.3 8.5 13.5 12.3 31.3 15.8 16.6 21.4 40.6 29.0 22.1 8.3 23.6 33.1 13.3 11.9 26.1 15.7 113.7 26.0 14.7 17.6 25.1 38.7 32.4 12.6 9.5 11.3 14.9 7.3 18.2 11.5 17.9 36.4 32.5 19.6 51.8 18.3 28.5 23.9 4.3 24.3 37.0 7.6 0.1 0.8 3.6 2.7 1.1 6.6 1.6 3.2 4.2 1.3 2.3 1.8 1.7 3.5 1.7 1.4 4.6 5.6 0.8 18.0 18.3 12.8 38.5 18.8 21.2 26.2 12.8 26.0 8.5 18.1 21.6 31.0 25.6 5.9 8.8 13.1 4.8 7.8 35.5 15.4 15.5 5.8 8.3 12.8 25.8 63.1 9.2 4.2 4.9 15.7 85.2 1.9 11.6 0.0 7.1 7.8 31.9 25.3 9.2 57.5 9.8 17.1 9.6 131.5 10.1 12.0 5.5 23.6 0.7 7.9 10.1 53.3 58.0 24.4 8.1 9.7 1.2 15.5 6.3 8.8 9.4 5.7 1.7 9.2 12.5 7.2 43.1 83.4 6.8 29.1 9.7 58.7 2.8 40.7 5.9 13.1 5.1 11.9 2.5 8.1 20.3 6.1 2.5 19.9 8.6 71.8 129.9 LRCH2 KIAA1495 ENSG00000130224 "Leucine rich repeats and calponin homology domain containing 2" Q5VUJ6 X 115110616-115234096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Excitatory neurons: 24.4;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 32.0;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 21.4;U-266/70: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003233, HPA076892" Approved Approved "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003233: AB_2265929, HPA076892: " "unprognostic (9.74e-2)" "unprognostic (9.48e-2)" "unprognostic (1.14e-2)" "unprognostic (4.22e-5)" "unprognostic (2.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (9.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.01e-2)" "unprognostic (1.84e-1)" "unprognostic (4.29e-5)" "unprognostic (1.09e-3)" "unprognostic (1.34e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-2)" 2.7 4.4 3.9 1.4 4.1 0.0 2.0 4.2 4.7 5.2 0.6 8.2 0.5 5.1 2.1 1.6 3.4 2.6 2.6 4.0 6.8 1.1 0.2 2.8 0.7 3.3 3.8 7.0 0.5 0.3 4.4 7.5 3.5 8.3 1.9 3.6 0.5 7.3 0.5 0.5 2.0 5.1 3.9 1.8 2.0 2.1 6.2 0.5 2.3 1.5 0.2 4.9 3.3 4.3 0.0 0.0 6.4 4.7 6.4 5.3 0.0 4.3 9.2 4.1 9.3 0.0 0.0 0.1 0.1 5.7 3.2 0.3 21.4 0.0 6.2 0.0 5.8 0.0 0.0 0.0 5.1 0.0 0.1 3.1 0.0 1.6 0.3 10.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 6.2 0.0 4.6 0.0 5.1 0.6 0.0 8.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 2.5 0.1 6.0 14.0 2.5 0.0 1.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.1 4.2 4.7 4.0 6.8 3.3 3.8 3.5 3.9 6.2 4.3 9.3 3.2 12.3 23.8 0.0 0.6 0.1 0.0 0.6 6.9 0.1 0.3 7.5 0.0 0.0 1.8 0.0 0.1 0.0 0.0 1.9 0.0 9.1 0.1 5.9 6.7 0.0 0.0 24.4 0.0 0.2 6.3 0.0 0.1 0.0 8.4 2.9 0.0 0.6 1.7 38.0 0.0 0.0 0.0 1.0 2.9 8.7 0.1 1.8 9.4 0.0 6.4 0.0 48.2 32.0 0.0 0.0 6.4 0.0 1.2 0.0 0.0 0.0 2.5 26.3 3.6 7.8 5.4 2.9 0.0 0.1 0.3 0.2 5.7 0.0 0.1 LSM11 FLJ38273 ENSG00000155858 "LSM11, U7 small nuclear RNA associated" P83369 5 157743712-157760709 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039587 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies" "HPA039587: AB_10796330" "unprognostic (3.99e-2)" "unprognostic (2.05e-1)" "unprognostic (2.38e-2)" "unprognostic (6.90e-2)" "unprognostic (2.32e-2)" "unprognostic (1.90e-1)" "unprognostic (6.61e-3)" "unprognostic (9.68e-3)" "unprognostic (1.70e-1)" "unprognostic (2.89e-2)" "unprognostic (3.77e-2)" "unprognostic (3.57e-1)" "unprognostic (1.62e-3)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (6.11e-2)" "unprognostic (3.01e-2)" 2.0 2.1 3.6 1.9 3.8 1.7 2.2 3.8 4.8 4.3 0.2 6.4 2.3 5.3 1.5 2.2 3.1 2.3 1.2 4.0 2.3 1.3 1.3 1.8 2.1 2.7 3.0 3.4 1.9 1.8 2.2 2.1 3.0 4.3 2.6 7.1 1.8 4.7 1.4 2.2 2.3 3.3 3.0 1.6 2.3 4.1 2.7 1.8 1.2 1.4 2.1 9.8 3.5 3.0 3.2 2.3 6.2 6.6 2.7 3.5 5.4 4.3 1.9 3.6 4.7 6.9 3.1 7.0 4.9 2.5 2.5 3.7 8.1 4.7 3.9 5.0 7.6 2.9 8.6 4.4 1.0 8.7 3.5 1.6 3.1 4.3 4.4 4.0 5.9 5.7 5.5 3.7 3.9 3.0 4.9 5.1 1.8 2.6 6.9 7.7 7.7 2.9 1.8 2.9 3.6 5.7 2.8 3.8 3.8 4.5 3.2 5.3 4.2 6.9 2.7 4.1 6.9 3.0 2.0 6.9 2.8 8.9 3.1 0.4 0.1 0.0 0.2 0.1 0.3 0.1 0.3 0.2 0.1 0.1 0.2 0.2 0.1 0.4 0.0 0.0 0.2 0.1 3.6 3.8 3.8 4.8 4.0 2.3 2.7 3.0 3.0 3.0 2.7 3.0 3.6 6.4 4.1 2.3 2.7 3.6 3.5 1.3 2.2 26.1 3.3 2.5 2.2 1.5 3.1 3.7 6.2 2.1 4.7 3.1 0.0 1.7 10.6 0.8 3.7 3.2 3.0 1.3 11.7 0.9 4.8 3.6 2.0 1.6 1.3 5.5 3.9 2.2 2.2 8.4 11.8 2.0 0.0 4.2 5.7 15.7 1.5 2.6 0.0 1.0 3.5 2.2 4.1 1.5 2.4 1.8 6.2 4.1 2.4 3.7 2.1 1.5 1.9 7.8 0.0 4.3 9.1 10.5 10.9 1.9 4.3 1.2 2.8 2.1 5.5 4.0 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1079.0;Cone photoreceptor cells: 779.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" 69.1 62.5 172.0 27.7 197.5 36.2 54.6 174.6 181.6 65.9 119.1 148.6 18.6 130.3 48.7 46.4 92.0 46.4 127.0 159.7 166.1 85.7 63.8 183.6 35.9 190.2 179.0 92.6 51.2 96.9 69.3 34.6 182.9 68.2 25.1 121.2 57.7 41.6 73.0 121.0 62.6 54.2 155.6 84.9 71.3 50.2 193.2 39.3 73.3 55.2 22.8 80.3 62.7 185.3 48.1 54.9 66.7 29.3 53.8 47.3 29.8 62.2 79.4 38.0 33.7 34.3 56.5 24.4 64.6 84.0 62.1 30.6 12.5 45.7 51.2 43.5 33.1 34.0 43.4 56.5 66.0 30.8 15.9 37.0 46.5 105.1 54.3 83.5 104.7 52.0 63.2 25.7 137.0 16.0 23.3 52.7 95.8 20.0 31.7 38.5 89.6 4.5 206.0 50.8 38.2 38.6 24.9 17.2 62.5 76.3 7.5 37.9 115.1 61.6 48.5 28.8 101.9 19.4 19.7 28.8 101.0 32.6 55.2 7.5 1.3 3.8 12.2 2.7 5.9 2.2 5.8 7.8 1.8 3.8 4.7 6.1 1.3 6.5 2.9 2.5 3.0 2.0 172.0 197.5 174.6 181.6 159.7 166.1 190.2 179.0 182.9 155.6 193.2 185.3 135.3 150.6 128.2 1079.0 68.7 154.4 74.9 43.0 60.3 387.7 52.5 50.9 246.1 61.5 70.7 80.9 779.8 52.6 120.5 35.4 0.0 113.3 9.6 140.6 124.4 164.3 36.1 57.6 320.6 114.6 62.1 108.2 65.2 180.1 77.7 194.3 132.1 47.9 52.1 117.8 367.5 27.2 22.4 59.7 46.3 11.8 43.8 74.8 71.2 342.9 59.0 107.8 158.6 494.6 410.7 193.5 17.7 112.5 81.0 89.7 22.5 20.6 71.3 398.5 105.2 95.5 136.7 62.6 33.7 43.5 191.5 69.9 131.2 76.5 19.7 78.8 MAML2 "KIAA1819, MAM3" ENSG00000184384 "Mastermind like transcriptional coactivator 2" Q8IZL2 11 95976598-96343195 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 690.5;Microglial cells: 579.9;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 311.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035223 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA035223: AB_10671101" "unprognostic (8.11e-2)" "unprognostic (2.51e-1)" "unprognostic (7.08e-2)" "unprognostic (9.07e-2)" "unprognostic (3.57e-3)" "unprognostic (3.32e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (8.05e-2)" "prognostic unfavorable (3.89e-4)" "unprognostic (9.11e-2)" "prognostic favorable (1.90e-4)" "unprognostic (9.76e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-1)" "unprognostic (7.19e-2)" 10.9 2.7 5.8 6.3 5.5 3.1 14.2 17.2 3.9 10.6 6.9 6.1 3.0 5.4 1.8 5.5 8.0 7.7 4.4 7.1 10.6 9.9 2.4 9.8 8.7 9.0 9.0 7.9 5.9 5.9 4.0 12.2 7.4 7.4 6.2 6.8 11.0 5.7 2.0 7.9 4.8 6.5 7.0 10.3 4.8 2.3 7.5 13.7 6.5 4.8 7.0 8.8 6.5 6.6 10.7 2.0 17.8 4.7 18.1 20.7 3.8 12.1 17.9 7.8 8.1 1.3 22.1 2.3 27.7 28.1 4.1 9.6 3.6 11.7 10.7 52.8 1.3 1.4 3.7 4.1 10.5 0.1 0.0 30.4 1.1 13.9 8.2 14.3 4.5 0.3 6.1 3.2 14.0 0.9 0.2 2.9 1.9 5.5 3.3 3.7 3.4 12.3 11.6 14.8 0.1 1.6 4.5 1.9 5.0 5.7 1.7 0.5 19.7 13.6 3.2 4.7 7.7 2.2 0.4 3.3 6.5 2.0 25.6 0.1 0.6 0.0 0.8 0.3 1.3 0.9 1.6 2.1 0.6 1.2 3.2 2.2 2.6 2.4 0.4 0.5 0.6 1.2 5.8 5.5 17.2 3.9 7.1 10.6 9.0 9.0 7.4 7.0 7.5 6.6 43.5 16.0 8.6 690.5 35.4 19.5 21.5 12.6 19.9 44.1 28.6 43.1 5.3 18.6 16.6 12.9 91.8 15.4 21.8 31.0 11.7 19.3 1.4 61.6 49.4 24.0 6.7 2.7 81.6 0.4 26.0 41.6 20.9 52.3 1.3 44.0 9.3 0.4 18.6 0.0 36.8 7.6 4.1 19.2 21.2 3.0 8.7 29.3 12.4 579.9 26.0 21.9 16.5 1300.8 311.4 15.0 16.8 8.6 18.1 19.1 9.4 17.1 24.2 25.9 32.9 3.6 51.5 0.6 0.8 19.4 13.5 13.0 38.1 9.0 14.3 19.2 MANBAL dJ1141E15.2 ENSG00000101363 "Mannosidase beta like" Q9NQG1 20 37289638-37317260 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052348 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria Nucleoplasm "HPA052348: AB_2681795" "unprognostic (1.86e-2)" "unprognostic (9.15e-2)" "unprognostic (1.85e-1)" "unprognostic (2.45e-2)" "unprognostic (3.12e-1)" "unprognostic (2.21e-3)" "prognostic unfavorable (7.07e-4)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (9.61e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "prognostic favorable (3.62e-4)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (8.03e-2)" "unprognostic (2.70e-2)" 51.5 70.5 68.6 23.4 68.2 7.3 51.6 67.3 76.3 67.5 68.8 92.7 35.0 86.1 57.1 64.4 71.6 30.6 43.5 70.0 71.3 57.8 42.0 40.5 16.7 69.4 68.8 66.9 45.5 49.8 57.5 33.2 70.2 77.4 40.1 28.0 45.9 61.8 24.4 58.3 48.7 65.4 68.4 34.2 60.3 42.7 71.9 22.6 55.1 17.9 25.4 81.2 58.5 68.3 66.0 126.5 63.0 63.9 101.0 73.1 54.5 89.9 93.1 85.1 66.6 150.3 87.4 16.9 104.8 109.8 86.7 88.5 60.3 140.2 57.9 12.7 62.5 17.8 51.3 135.3 109.0 19.1 10.8 80.1 97.8 79.3 130.1 85.4 60.2 22.1 29.1 18.1 86.2 77.3 24.0 25.1 50.4 109.6 117.0 14.4 82.7 19.9 81.6 90.3 60.4 68.9 91.1 135.1 76.3 53.7 91.1 30.2 66.6 155.5 58.1 88.6 70.3 24.0 34.9 14.0 111.8 10.4 82.3 12.3 22.8 33.2 14.9 27.0 17.0 24.3 17.9 18.0 21.0 25.6 21.4 20.9 33.8 21.1 21.4 29.2 12.8 16.7 68.6 68.2 67.3 76.3 70.0 71.3 69.4 68.8 70.2 68.4 71.9 68.3 19.9 25.6 27.1 10.1 9.5 30.1 87.3 84.2 33.0 22.7 41.3 47.9 19.6 35.8 42.1 44.1 4.2 97.0 9.1 24.7 39.2 74.5 6.6 23.8 26.6 28.5 30.5 2.1 8.6 109.3 133.4 42.6 23.9 20.4 7.6 31.5 28.9 22.5 30.3 20.2 10.7 36.7 50.8 15.1 20.6 8.0 46.9 12.3 46.2 6.5 18.0 71.4 18.6 13.0 8.4 103.2 48.4 68.4 16.8 96.0 40.9 61.1 29.9 15.4 19.7 27.4 38.7 26.4 43.8 36.5 30.4 76.9 8.4 40.7 34.8 124.7 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.9" "Cell type enhanced" "Detected in many" "Adipocytes: 29.5;Astrocytes: 16.6;Endothelial cells: 21.1;Excitatory neurons: 15.8;Hepatic stellate cells: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "CAB012961: AB_2533144, HPA045069: AB_2679207" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 27.5 6.8 52.3 7.9 56.0 1.1 24.0 48.2 70.9 15.1 40.6 7.3 1.9 15.5 5.8 9.4 16.7 8.7 18.9 55.2 49.6 18.6 4.8 16.8 9.4 48.2 47.2 12.5 5.7 5.4 28.4 8.3 48.2 18.2 2.6 8.6 7.2 7.2 6.4 7.5 8.3 9.4 47.4 16.3 10.9 6.1 50.2 3.5 11.0 5.8 6.1 11.6 12.3 51.0 2.8 6.8 7.4 27.8 9.5 14.3 0.2 10.2 7.4 6.8 2.7 2.8 5.2 0.0 8.7 9.9 11.3 6.9 4.9 4.2 0.5 13.9 3.4 10.1 10.4 0.6 10.9 2.5 15.0 19.9 12.3 1.9 0.8 7.7 15.2 10.6 8.1 26.8 6.9 12.4 0.5 9.4 0.6 8.4 7.7 26.7 0.1 9.9 10.3 0.0 6.8 18.4 9.0 3.7 7.7 0.9 12.2 7.9 24.0 20.4 16.5 1.5 3.7 1.2 3.2 11.8 10.4 2.9 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 52.3 56.0 48.2 70.9 55.2 49.6 48.2 47.2 48.2 47.4 50.2 51.0 29.5 0.0 1.1 16.6 2.2 1.9 1.8 3.2 8.0 3.3 1.1 1.5 6.6 1.5 1.7 0.0 6.2 0.0 1.8 0.1 1.9 1.0 4.7 0.6 1.8 21.1 0.0 0.4 15.8 0.2 0.4 2.7 0.5 1.7 0.0 0.1 20.0 2.1 0.3 0.0 3.6 0.2 2.0 1.3 2.1 9.7 3.1 0.5 5.4 13.1 0.1 5.9 0.0 1.0 0.9 0.7 0.0 2.2 1.6 2.9 0.0 1.9 1.3 11.4 0.0 0.6 1.8 1.3 3.2 1.8 1.3 0.0 3.3 0.7 0.1 1.1 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 336.9;Early spermatids: 267.2;Proximal enterocytes: 235.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 49.1;neutrophil: 21.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 49.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported Nucleoplasm NA NA 46000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 99.5 64.3 178.7 42.4 162.3 45.2 86.3 113.0 200.9 93.3 86.0 117.2 103.1 74.9 27.4 129.6 71.6 65.3 65.4 168.6 132.7 49.4 21.2 71.3 37.8 135.6 148.7 78.7 33.7 61.2 55.8 70.2 142.3 49.2 91.9 71.5 61.0 43.3 51.7 77.6 113.2 58.7 127.4 57.4 86.4 31.6 129.5 31.4 58.0 57.0 49.3 64.8 89.0 130.9 56.3 30.0 62.2 35.7 153.7 202.4 35.1 40.7 101.1 63.4 75.3 36.4 110.0 56.3 39.7 115.5 73.2 20.6 53.3 47.8 61.0 106.9 61.8 17.3 31.6 61.8 154.2 13.0 46.2 125.8 27.3 72.5 32.2 96.1 163.7 60.3 24.3 70.0 85.2 147.1 59.2 21.5 16.9 113.6 26.1 68.9 37.3 127.4 58.0 35.0 55.2 39.3 23.2 81.8 24.1 50.5 53.5 30.7 117.2 41.7 35.4 48.4 14.5 79.1 39.3 29.6 83.3 27.1 30.0 6.2 5.1 49.1 1.6 3.7 2.6 2.3 3.7 3.0 2.8 2.5 2.6 2.9 21.5 2.2 2.0 2.8 6.6 2.8 178.7 162.3 113.0 200.9 168.6 132.7 135.6 148.7 142.3 127.4 129.5 130.9 95.5 22.4 17.5 7.5 10.7 9.8 22.2 11.4 5.7 30.4 23.3 19.9 15.4 20.0 13.0 9.2 22.9 77.6 15.2 336.9 23.5 39.8 267.2 24.8 25.1 68.1 54.7 6.1 7.7 61.2 134.2 34.7 79.0 15.7 2.5 19.1 71.7 7.0 45.2 8.4 10.3 159.3 22.4 26.4 12.3 176.0 32.3 20.6 23.2 7.5 24.5 67.0 13.4 7.1 9.8 118.8 167.2 27.4 6.2 13.5 235.6 23.9 24.7 41.5 19.7 18.8 29.3 10.9 19.8 15.8 13.2 33.8 14.5 40.0 94.9 22.4 MATN3 "EDM5, HOA" ENSG00000132031 "Matrilin 3" O15232 2 19992052-20012668 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.2;placenta: 11.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 38.5;Sertoli cells: 26.3" "Cancer enhanced" "Detected in all" "pancreatic cancer: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "Hep G2: 143.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 1.7" HPA051250 Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 440000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum, Golgi apparatus" "HPA051250: AB_2681406" "unprognostic (3.47e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (7.57e-2)" "unprognostic (2.75e-2)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.62e-5)" "unprognostic (1.27e-1)" "unprognostic (4.84e-2)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (2.54e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.51e-1)" "unprognostic (7.04e-2)" "unprognostic (3.15e-2)" 2.2 0.6 5.1 0.5 3.2 0.0 2.7 3.4 5.7 2.5 2.5 0.6 0.4 2.1 0.9 0.5 1.9 2.1 0.4 3.4 3.9 1.9 0.0 13.2 0.3 5.2 6.0 0.7 0.4 0.4 0.3 11.3 5.2 1.6 0.5 0.3 0.6 4.6 0.3 0.8 0.4 1.7 4.7 0.3 1.8 0.9 7.6 0.1 1.3 0.6 0.3 0.8 1.2 3.6 6.4 4.9 16.1 0.1 4.5 9.7 1.0 2.0 1.1 6.5 8.2 4.7 2.7 0.0 0.8 1.7 6.2 1.1 0.4 12.7 9.2 0.0 0.4 0.0 1.1 143.4 1.1 0.0 0.0 21.3 0.7 7.1 1.7 4.5 8.7 0.0 0.0 0.0 13.8 2.5 0.0 0.0 5.0 0.2 2.4 0.0 0.0 0.0 19.5 4.5 0.1 2.1 10.6 1.8 6.5 27.1 19.2 0.1 4.9 9.5 11.4 0.4 1.2 0.1 0.0 0.0 1.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.2 3.4 5.7 3.4 3.9 5.2 6.0 5.2 4.7 7.6 3.6 1.6 38.5 2.2 0.0 0.0 0.3 0.3 2.6 0.0 0.0 5.4 1.3 0.3 0.0 2.3 1.8 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.3 0.8 2.8 0.0 0.0 0.1 0.2 1.9 1.9 0.0 0.5 0.0 4.4 0.0 0.0 0.1 0.0 0.2 0.0 4.1 0.0 0.3 0.4 1.5 0.1 3.6 4.7 0.0 0.0 0.0 0.5 0.2 1.1 0.0 4.5 0.0 0.3 0.0 0.8 1.6 0.0 26.3 0.8 6.8 0.0 1.3 0.0 0.1 0.1 0.1 6.3 0.0 0.2 MEIS2 "HsT18361, MRG1" ENSG00000134138 "Meis homeobox 2" O14770 15 36889204-37101299 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 522.3;Cone photoreceptor cells: 254.4;Excitatory neurons: 164.7;Hepatic stellate cells: 207.4;Oligodendrocyte precursor cells: 262.4;Oligodendrocytes: 219.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 2.9;eosinophil: 2.4" "Lineage enriched" "Detected in single" 29 "granulocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 114.0;SH-SY5Y: 104.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 68.4;olfactory bulb: 177.4" "HPA003256, CAB004999" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB004999: AB_425545, HPA003256: AB_1079356" "unprognostic (4.33e-2)" "unprognostic (1.94e-2)" "unprognostic (6.71e-4)" "unprognostic (2.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.24e-1)" "unprognostic (5.23e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-1)" "unprognostic (4.73e-2)" "unprognostic (7.97e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.64e-7)" "unprognostic (6.47e-2)" "unprognostic (8.15e-2)" "unprognostic (8.79e-5)" "unprognostic (1.15e-1)" 11.1 21.9 14.4 5.3 50.4 0.0 7.4 11.7 24.9 20.9 0.6 33.2 20.6 37.0 4.1 14.2 23.3 17.8 15.7 16.0 14.7 11.1 6.9 8.4 3.4 19.2 25.7 21.1 13.4 3.5 16.4 8.6 20.0 37.7 6.4 18.8 56.8 21.6 0.7 4.4 8.3 36.3 18.0 7.6 14.1 1.6 11.8 11.1 5.4 9.5 3.4 25.6 13.5 20.3 13.3 12.0 15.3 43.6 16.7 20.6 3.6 28.3 15.6 32.9 18.4 17.2 10.8 7.6 0.7 114.0 20.8 22.4 26.9 7.2 18.1 10.9 17.3 58.8 15.8 13.9 28.6 17.5 57.2 27.3 6.3 22.3 6.6 43.2 19.1 2.8 20.1 0.1 6.4 14.3 0.1 6.7 0.2 15.8 3.9 0.0 11.1 4.1 0.0 25.7 11.9 104.0 10.8 7.1 8.0 16.5 3.4 13.3 27.3 37.6 4.6 10.1 12.1 7.5 8.1 14.6 44.3 9.7 9.6 2.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 50.4 11.7 24.9 16.0 14.7 19.2 25.7 20.0 18.0 11.8 20.3 6.5 0.0 7.3 522.3 3.4 17.5 97.3 14.1 79.1 43.8 21.0 16.3 23.9 77.2 11.4 1.8 254.4 23.3 1.0 1.0 0.0 58.4 15.2 10.5 17.1 67.2 1.8 5.3 164.7 27.1 10.0 61.7 25.5 0.8 63.3 14.9 207.4 9.6 3.4 3.3 5.0 0.4 30.5 6.5 6.1 7.4 47.8 1.1 8.8 21.5 0.6 10.7 0.0 262.4 219.7 25.7 0.3 41.3 1.8 38.3 1.4 0.1 26.5 135.9 32.9 14.7 46.4 3.6 3.1 23.8 6.1 4.5 2.3 31.2 1.0 54.1 MESP2 "bHLHc6, SCDO2" ENSG00000188095 "Mesoderm posterior bHLH transcription factor 2" Q0VG99 15 89760591-89778754 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.7;Exocrine glandular cells: 3.8;Rod photoreceptor cells: 7.0;Spermatogonia: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.1;U-2197: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.13e-1)" "unprognostic (1.76e-2)" "unprognostic (3.75e-2)" "unprognostic (8.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.50e-3)" "unprognostic (6.59e-4)" "unprognostic (5.58e-2)" "unprognostic (4.00e-1)" "unprognostic (5.90e-2)" "unprognostic (3.14e-5)" "unprognostic (2.69e-1)" "unprognostic (1.01e-2)" "unprognostic (2.50e-1)" "unprognostic (3.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.11e-1)" 0.5 0.2 0.9 0.0 0.9 0.0 0.5 0.7 1.2 0.8 0.4 0.5 0.0 0.0 0.7 0.4 0.1 0.3 0.1 0.9 0.9 0.1 0.0 0.0 0.1 0.9 0.9 0.0 0.1 0.1 0.0 0.0 1.0 0.3 0.4 0.9 0.4 0.2 0.0 0.4 0.2 0.0 0.8 0.0 0.1 0.7 0.8 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.0 1.1 0.0 0.4 0.6 0.1 0.2 0.2 0.1 0.5 0.1 0.3 0.5 0.0 0.1 0.1 0.0 1.1 0.3 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.6 0.2 0.4 0.2 0.0 0.3 0.5 0.3 0.0 0.1 0.2 0.0 0.1 0.2 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.1 0.5 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.9 0.7 1.2 0.9 0.9 0.9 0.9 1.0 0.8 0.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 1.5 0.4 0.0 1.3 0.0 0.0 0.6 0.1 1.2 1.9 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.3 3.8 0.0 0.8 0.0 0.0 0.0 0.4 0.4 0.2 0.5 0.0 0.3 0.8 0.0 0.3 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.5 0.2 0.4 0.0 0.6 0.0 0.7 0.7 7.0 0.0 0.3 0.3 1.2 2.1 0.2 0.0 0.1 0.0 0.9 0.7 0.9 MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 565.4;Distal enterocytes: 398.7;Pancreatic endocrine cells: 535.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Cell line enhanced" "Detected in many" "BJ: 209.1;BJ hTERT+: 238.6;LHCN-M2: 191.3;RPTEC TERT1: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 174.8 16.1 100.8 22.9 91.0 18.9 92.0 87.2 123.4 26.8 48.0 81.9 36.9 17.7 9.9 139.9 34.3 44.8 101.9 96.9 75.9 71.0 106.9 72.0 13.5 72.5 86.6 6.1 7.8 3.6 12.5 41.6 70.9 25.8 60.4 6.2 102.1 27.5 66.0 38.1 50.3 27.8 63.0 44.9 38.2 6.2 107.2 10.0 18.9 64.9 21.3 42.5 39.4 88.6 52.4 46.2 0.1 0.5 76.8 90.0 6.2 209.1 238.6 45.3 72.2 1.2 21.0 14.0 56.9 71.3 13.7 2.1 0.4 27.9 25.2 23.5 0.9 1.6 31.4 0.4 27.7 0.3 1.7 34.2 16.1 85.0 92.4 25.6 97.5 1.0 0.3 3.0 191.3 5.6 0.5 0.9 0.5 33.6 71.5 0.2 24.6 109.4 170.4 5.9 26.5 2.1 36.3 70.4 12.6 2.0 3.5 2.1 125.9 49.5 14.8 121.0 29.1 0.5 0.4 43.4 102.4 3.4 156.6 20.6 8.3 36.0 0.5 84.7 2.8 4.9 0.5 1.1 9.2 0.5 0.2 0.2 1.5 2.0 57.2 89.8 0.0 17.1 100.8 91.0 87.2 123.4 96.9 75.9 72.5 86.6 70.9 63.0 107.2 88.6 565.4 195.5 108.6 83.2 8.5 22.8 11.9 14.1 5.7 22.8 25.2 19.9 53.7 118.7 32.2 42.3 0.0 84.6 16.1 398.7 168.3 99.4 4.1 100.0 36.4 207.7 88.6 30.7 39.0 160.7 154.6 71.5 47.9 132.1 8.8 0.1 17.2 148.7 123.9 0.0 48.9 239.1 63.1 32.8 86.3 5.8 32.6 77.8 21.4 52.5 235.2 54.5 2.1 43.2 5.8 535.2 201.0 69.6 36.2 18.5 134.2 102.0 48.0 7.8 85.5 22.3 141.4 0.7 1.7 64.7 22.3 72.7 9.3 1.1 74.0 6.0 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 129.3;Basal squamous epithelial cells: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 156.1;AF22: 132.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 5.9 2.5 6.9 5.0 7.7 1.7 5.3 17.2 5.0 7.0 6.5 17.3 5.7 8.9 4.9 7.0 6.4 6.8 9.3 7.0 4.9 7.3 4.2 6.5 2.2 3.6 10.4 4.4 3.5 2.8 4.2 6.2 4.9 10.4 10.6 12.3 4.9 12.9 0.7 2.9 5.8 12.3 2.1 1.0 3.8 3.6 8.2 2.3 4.2 2.2 3.1 11.7 6.2 4.4 33.2 156.1 132.5 16.7 8.1 9.2 14.6 16.2 17.8 19.7 20.7 31.0 9.7 10.6 6.5 21.9 58.4 22.5 11.0 15.1 23.0 1.3 11.0 2.7 24.3 1.1 2.8 0.3 1.2 12.1 7.0 16.1 15.8 20.4 23.1 5.1 2.1 3.2 9.6 8.0 5.3 0.5 32.7 5.1 10.0 3.9 28.9 0.4 18.7 36.2 7.1 3.5 7.4 23.5 10.1 42.7 19.2 0.2 13.7 7.2 1.0 34.1 17.0 2.8 1.2 0.4 13.5 0.3 31.3 0.5 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.7 0.0 0.1 0.4 0.0 0.1 6.9 7.7 17.2 5.0 7.0 4.9 3.6 10.4 4.9 2.1 8.2 4.4 16.5 35.3 20.7 129.3 0.7 21.4 31.5 24.7 82.6 10.7 8.5 13.2 4.8 8.6 19.6 23.9 18.8 9.1 1.3 22.6 1.9 13.4 2.2 39.8 8.9 25.4 12.1 2.7 15.5 8.7 26.9 16.2 10.7 38.5 1.3 13.4 69.9 4.0 1.5 69.0 44.3 9.0 2.0 2.5 5.8 7.9 30.1 1.2 3.6 23.4 0.0 37.0 0.0 66.4 59.2 7.3 17.2 41.3 0.2 8.2 11.3 1.5 19.3 2.9 6.6 3.7 3.3 0.3 2.4 36.1 10.1 20.0 0.8 9.7 20.0 49.2 MINDY2 "FAM63B, KIAA1164" ENSG00000128923 "MINDY lysine 48 deubiquitinase 2" Q8NBR6 15 58771192-58861900 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Collecting duct cells: 82.8;Endometrial ciliated cells: 66.4;Extravillous trophoblasts: 108.7;Glandular and luminal cells: 73.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-2197: 72.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051103, HPA063669" Approved Enhanced Nucleoplasm No No "Cluster 18: Basophils - Vesicular transport" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA051103: AB_2681345, HPA063669: AB_2685082" "unprognostic (4.71e-2)" "unprognostic (8.92e-3)" "unprognostic (4.63e-2)" "unprognostic (4.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (8.60e-2)" "unprognostic (7.23e-2)" "unprognostic (7.09e-2)" "unprognostic (2.36e-3)" "unprognostic (4.74e-2)" "prognostic favorable (3.00e-8)" "unprognostic (2.53e-1)" "unprognostic (3.59e-1)" "unprognostic (6.76e-2)" "unprognostic (4.77e-2)" 9.4 5.4 9.3 5.7 9.6 3.8 6.6 15.0 10.4 7.0 8.9 5.4 3.5 7.1 4.6 7.1 6.8 6.3 10.8 8.0 11.6 10.1 3.5 7.7 4.1 10.5 11.0 6.8 3.3 7.3 4.9 9.0 10.0 8.9 3.9 16.3 4.9 6.1 3.4 7.1 3.6 8.5 9.2 6.1 4.8 3.9 11.2 5.9 9.6 8.9 3.7 8.0 5.2 10.3 10.9 5.3 7.3 4.4 10.7 19.7 11.5 9.8 20.8 3.0 4.3 8.4 5.4 5.6 10.5 11.8 5.3 10.3 13.4 7.9 4.6 5.6 4.9 7.8 5.7 7.6 6.6 5.9 6.9 8.7 12.9 3.5 8.0 11.3 7.4 5.9 13.7 6.1 7.1 1.4 7.4 4.4 15.7 1.4 2.7 3.3 21.0 6.0 8.9 12.1 6.7 4.9 7.1 10.0 17.9 15.3 3.0 12.5 8.7 4.2 3.7 72.5 4.3 5.4 8.3 5.4 9.4 9.5 10.2 3.0 0.7 1.3 1.1 0.6 2.1 0.9 1.0 1.3 0.2 1.6 0.8 1.2 1.4 0.8 1.4 1.1 0.9 0.5 9.3 9.6 15.0 10.4 8.0 11.6 10.5 11.0 10.0 9.2 11.2 10.3 65.2 147.4 39.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 43.8 44.8 0.0 0.0 18.0 82.8 0.0 65.2 27.5 0.0 46.9 44.4 0.0 66.4 46.8 19.8 0.0 0.0 0.0 21.2 108.7 21.7 0.0 73.2 11.4 11.6 0.0 0.0 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 32.4 0.0 0.0 7.5 0.0 0.0 14.2 28.4 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 53.2 11.3 17.6 0.0 0.0 MORC4 "FLJ11565, ZCW4, ZCWCC2" ENSG00000133131 "MORC family CW-type zinc finger 4" Q8TE76 X 106813871-107000212 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 79.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 131.4;Alveolar cells type 2: 130.4;Cytotrophoblasts: 329.8;Syncytiotrophoblasts: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000395, HPA015547, HPA050250" Enhanced Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA000395: AB_1079405, HPA015547: AB_2669216, HPA050250: AB_2681063" "prognostic unfavorable (3.56e-5)" "unprognostic (3.30e-3)" "unprognostic (1.09e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (6.29e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (5.56e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.60e-2)" "unprognostic (6.57e-2)" "unprognostic (4.89e-2)" "unprognostic (8.69e-2)" 13.4 30.9 24.8 7.8 35.5 11.8 12.2 47.8 51.0 12.1 17.8 8.5 10.4 11.5 16.3 9.6 10.4 10.1 7.0 32.4 22.4 10.8 21.1 8.8 5.6 11.1 11.4 17.4 15.1 11.7 6.2 79.9 16.6 12.4 10.8 22.3 10.9 11.5 20.2 18.7 10.0 11.4 3.9 6.0 8.4 20.2 16.6 5.6 10.2 10.3 7.0 7.5 11.1 55.7 29.8 121.0 11.4 26.4 35.0 40.3 60.5 28.7 30.8 14.6 18.3 64.6 13.1 3.7 14.2 30.5 23.9 22.5 39.8 25.5 17.1 4.6 23.0 6.4 40.7 27.1 25.6 4.7 13.9 20.8 24.3 19.6 28.6 85.7 13.1 4.1 3.9 41.4 32.7 26.7 10.7 6.4 8.9 82.0 45.2 4.2 22.9 4.3 47.0 23.3 9.2 11.5 35.4 33.9 23.0 15.9 19.7 5.0 12.6 22.5 21.4 44.7 15.7 11.1 16.2 11.5 24.0 3.8 16.2 8.3 1.5 1.8 1.9 1.3 1.7 1.7 1.9 1.5 0.7 2.7 2.1 1.7 3.7 1.5 1.7 2.5 1.5 0.4 24.8 35.5 47.8 51.0 32.4 22.4 11.1 11.4 16.6 3.9 16.6 55.7 8.6 131.4 130.4 6.2 5.1 17.5 19.1 4.9 21.1 5.4 11.5 9.5 3.0 10.0 61.8 5.5 4.2 329.8 10.4 3.6 21.5 9.9 0.9 6.2 11.5 13.6 1.8 0.4 4.2 7.4 28.2 33.4 10.2 15.5 66.3 10.3 7.5 24.0 23.4 1.7 6.5 10.5 6.1 2.1 5.0 1.8 11.1 8.2 12.4 3.7 0.3 6.7 3.1 15.1 8.7 7.5 6.7 11.7 5.8 16.4 4.4 12.7 62.2 7.2 26.3 16.9 12.0 9.9 26.6 19.7 16.1 257.8 11.9 10.1 10.1 11.8 MPP3 DLG3 ENSG00000161647 "Membrane palmitoylated protein 3" Q13368 17 43800799-43833170 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.2;heart muscle: 11.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.2;Early spermatids: 38.4;Late spermatids: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021818, HPA024742" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA021818: AB_1854086, HPA024742: AB_1854087" "unprognostic (1.94e-1)" "unprognostic (1.38e-1)" "unprognostic (2.30e-2)" "unprognostic (2.23e-5)" "unprognostic (4.59e-3)" "unprognostic (5.63e-2)" "unprognostic (5.07e-6)" "unprognostic (2.01e-1)" "unprognostic (1.03e-2)" "unprognostic (3.43e-2)" "unprognostic (1.77e-1)" "unprognostic (1.84e-3)" "unprognostic (8.02e-11)" "unprognostic (9.98e-3)" "unprognostic (1.50e-2)" "unprognostic (1.66e-1)" "unprognostic (1.75e-2)" 1.4 0.6 2.4 0.3 1.5 0.0 1.4 10.2 2.0 1.5 2.8 0.9 0.4 0.7 1.8 1.0 1.1 0.7 11.8 1.9 2.4 1.1 0.3 2.2 0.2 4.9 2.2 0.6 2.2 0.3 1.8 0.4 4.4 1.6 0.3 0.9 0.5 0.9 0.2 1.0 0.5 0.6 1.5 1.2 1.0 0.8 3.4 0.0 0.7 0.1 0.2 0.8 1.1 2.0 0.5 1.4 0.5 0.6 0.9 1.2 0.0 1.1 0.4 1.1 0.4 0.9 0.8 0.0 0.3 0.8 0.7 0.5 1.1 1.1 1.6 0.0 1.3 0.2 3.3 0.7 0.1 0.0 0.0 0.7 2.3 1.5 2.1 1.4 0.3 0.0 0.5 0.0 0.6 1.1 0.0 0.0 0.6 0.5 1.1 0.0 0.9 0.0 1.8 0.0 4.8 1.1 0.7 1.5 0.3 0.8 2.6 1.1 1.0 1.2 1.9 0.5 1.4 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.5 10.2 2.0 1.9 2.4 4.9 2.2 4.4 1.5 3.4 2.0 12.1 12.8 4.1 3.9 0.0 4.0 8.3 2.7 5.7 2.7 3.2 4.8 29.2 7.2 5.4 1.8 0.0 0.1 0.0 1.2 0.0 3.9 38.4 0.8 1.9 5.3 1.2 0.8 3.6 1.4 0.6 3.3 12.8 1.9 1.3 1.1 3.6 0.7 1.1 10.1 5.4 1.2 0.0 0.0 3.9 76.0 3.7 1.1 1.8 1.0 1.9 0.8 0.0 3.5 10.0 2.9 3.4 2.6 0.0 8.1 0.4 0.3 0.8 1.7 6.6 0.8 2.9 0.8 2.6 4.7 2.7 0.1 0.5 0.3 2.3 3.2 NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.1;Inhibitory neurons: 161.7;Oligodendrocyte precursor cells: 713.8;Oligodendrocytes: 224.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "TIME: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" 19.6 2.7 17.4 8.2 18.3 1.6 15.2 8.0 17.7 11.7 0.0 12.3 3.7 10.1 4.3 8.6 7.2 7.5 26.6 17.5 20.3 4.6 1.9 11.1 4.1 24.6 17.9 3.7 4.4 5.2 5.2 11.8 15.1 7.5 5.4 5.4 7.8 6.7 4.8 7.7 6.2 10.3 9.9 3.6 5.3 4.4 21.8 2.8 9.4 6.7 3.7 14.9 12.6 32.5 1.6 2.9 29.0 3.8 84.3 69.5 51.7 44.6 43.0 35.5 30.9 0.0 15.7 0.6 0.7 61.4 19.4 21.5 22.0 14.9 28.4 2.5 3.2 1.4 5.6 0.0 22.5 0.2 19.1 30.6 5.4 62.4 36.0 94.9 80.7 1.8 0.8 2.6 29.8 0.4 0.0 0.1 42.4 0.7 1.7 3.9 65.0 9.3 4.8 4.3 21.9 4.5 11.1 47.6 14.5 19.2 0.4 1.2 187.8 54.5 11.1 54.7 39.4 8.1 2.3 0.2 59.2 5.9 47.5 3.4 0.5 0.1 0.2 0.3 0.1 0.3 0.2 0.0 2.1 0.3 0.2 0.1 0.0 0.1 0.3 0.5 0.0 0.3 17.4 18.3 8.0 17.7 17.5 20.3 24.6 17.9 15.1 9.9 21.8 32.5 77.4 3.2 1.5 169.1 3.1 11.0 2.2 5.9 8.0 34.6 4.8 4.3 29.2 1.5 4.8 12.9 0.0 14.9 0.9 4.7 0.0 13.0 3.6 1.6 6.4 39.3 52.8 1.7 98.2 8.3 54.1 45.8 8.2 4.4 17.7 54.5 21.0 0.7 14.5 25.2 161.7 3.4 6.1 18.3 15.8 3.8 10.8 15.1 23.2 69.3 60.6 11.8 1.0 713.8 224.6 21.7 4.2 0.7 4.9 2.3 0.9 0.6 3.5 4.0 6.6 119.3 18.8 0.6 2.6 16.9 7.0 15.7 2.0 6.6 5.0 3.2 NFASC "FLJ46866, KIAA0756, NF, NRCAML" ENSG00000163531 Neurofascin O94856 1 204828651-205022822 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.0;Excitatory neurons: 148.4;Horizontal cells: 220.4;Inhibitory neurons: 139.0;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 226.6;Rod photoreceptor cells: 195.5" "Cancer enriched" "Detected in many" 5 "glioma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 27.6;fHDF/TERT166: 50.3;hTERT-RPE1: 24.0;SCLC-21H: 22.8;U-138 MG: 62.7;U-87 MG: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008832 Enhanced NA NA 2200000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "HPA008832: AB_1854411" "unprognostic (1.71e-1)" "unprognostic (1.07e-1)" "unprognostic (2.62e-1)" "unprognostic (3.39e-2)" "unprognostic (6.65e-2)" "unprognostic (1.18e-2)" "unprognostic (3.71e-3)" "unprognostic (3.37e-1)" "unprognostic (6.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.21e-5)" "unprognostic (3.76e-1)" "prognostic unfavorable (2.93e-5)" "unprognostic (1.56e-3)" "unprognostic (1.91e-1)" "unprognostic (6.90e-2)" "unprognostic (5.26e-3)" 5.2 7.5 7.8 3.7 31.5 0.1 3.2 8.4 15.2 5.0 0.0 8.6 4.5 8.3 9.0 10.0 12.1 5.9 15.3 10.7 5.6 9.8 1.9 5.0 2.3 13.1 14.1 10.1 5.9 1.0 5.6 10.6 7.8 7.5 5.9 22.6 2.1 16.3 3.0 4.3 5.0 14.2 3.9 6.5 4.4 1.5 35.6 0.6 2.9 3.8 2.9 9.4 7.7 50.1 0.0 0.1 3.1 0.1 0.4 1.0 0.1 27.6 0.0 19.9 5.9 0.2 0.1 0.0 0.1 50.3 18.5 13.4 0.6 0.8 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 12.7 0.7 24.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 7.0 0.9 0.3 0.0 2.3 0.0 0.0 0.0 22.8 1.3 0.0 1.5 0.0 2.0 0.3 0.0 0.0 62.7 13.5 0.1 0.0 0.0 0.0 0.0 31.3 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 31.5 8.4 15.2 10.7 5.6 13.1 14.1 7.8 3.9 35.6 50.1 2.5 0.0 0.6 64.3 0.0 2.2 1.5 1.9 0.6 151.0 1.7 10.5 23.9 1.5 1.5 0.0 12.5 0.5 0.0 0.3 0.0 0.2 7.3 0.5 0.4 7.6 37.8 0.0 148.4 0.0 0.5 14.2 1.1 0.1 0.0 0.1 3.3 1.7 0.4 220.4 139.0 6.0 0.0 0.6 1.9 17.9 6.5 0.4 1.8 15.0 0.0 14.2 0.0 87.9 226.6 0.5 0.5 5.7 0.0 1.1 0.0 1.5 5.9 195.5 52.6 2.3 49.9 1.7 3.9 5.5 4.7 0.7 0.3 0.7 1.0 0.8 NFE2L3 Nrf3 ENSG00000050344 "Nuclear factor, erythroid 2 like 3" Q9Y4A8 7 26152198-26187137 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7;placenta: 34.4" "Group enriched" "Detected in many" 14 "Cytotrophoblasts: 305.9;Syncytiotrophoblasts: 698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 133.5;NTERA-2: 113.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055889 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Vesicles" "HPA055889: AB_2682958" "unprognostic (4.99e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-3)" "unprognostic (5.37e-2)" "unprognostic (8.41e-2)" "unprognostic (4.00e-3)" "unprognostic (7.29e-3)" "unprognostic (1.87e-1)" "unprognostic (2.12e-1)" "unprognostic (9.88e-2)" "prognostic unfavorable (6.62e-5)" "unprognostic (2.32e-1)" "prognostic unfavorable (7.58e-12)" "prognostic favorable (2.14e-4)" "unprognostic (2.40e-1)" "unprognostic (8.25e-2)" "unprognostic (4.13e-3)" 3.6 3.1 4.2 10.6 7.3 2.5 2.2 19.5 19.7 1.5 2.3 6.3 8.0 2.2 0.2 2.4 1.6 4.3 1.4 6.3 4.8 2.5 1.6 4.8 8.0 7.0 4.6 1.1 4.8 0.4 1.3 34.4 7.2 1.4 4.8 5.1 3.2 0.6 2.7 7.3 5.7 1.0 5.1 7.6 7.3 1.4 6.3 5.9 1.0 0.2 7.0 4.8 1.5 10.8 40.9 3.5 1.6 4.0 0.0 0.0 133.5 7.9 15.2 15.0 27.3 26.2 68.8 3.0 51.2 0.8 57.5 8.6 6.0 13.4 33.7 27.9 8.5 5.7 7.0 19.8 10.5 5.0 52.3 1.3 1.6 6.2 2.3 22.4 35.0 11.3 8.6 69.9 3.0 5.5 3.5 8.8 113.9 11.1 13.9 5.0 0.4 20.5 20.5 40.5 12.3 14.7 0.2 3.2 1.2 37.5 1.9 3.0 76.0 1.4 2.3 0.6 32.6 42.0 72.2 3.4 0.2 17.5 53.1 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.2 0.0 0.2 0.6 0.1 4.2 7.3 19.5 19.7 6.3 4.8 7.0 4.6 7.2 5.1 6.3 10.8 14.6 6.4 2.8 3.9 4.6 1.8 4.2 12.7 5.2 1.4 3.1 2.3 1.9 14.3 6.9 11.0 0.0 305.9 1.6 6.1 0.0 13.0 1.0 6.1 1.8 7.6 1.2 12.0 3.8 5.3 33.9 2.8 14.3 6.4 27.9 35.2 2.2 0.3 24.3 0.0 4.4 6.6 12.2 15.6 17.2 0.3 0.0 16.7 1.8 2.8 11.1 1.1 4.1 1.5 11.6 15.6 4.1 0.0 18.2 10.4 2.7 0.5 8.9 1.9 0.0 2.9 2.7 0.6 7.1 5.5 1.6 698.6 9.0 4.8 9.8 6.7 NHSL2 ENSG00000204131 "NHS like 2" Q5HYW2 X 71910818-72161750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 101.2;monocytes: 57.7;Prostatic glandular cells: 90.5;Urothelial cells: 80.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.6" "Group enriched" "Detected in many" 4 "dendritic cells: 4.1;granulocytes: 15.6;monocytes: 7.1" "Cell line enhanced" "Detected in some" "AF22: 25.2;EFO-21: 29.5;HUVEC TERT2: 27.8;TIME: 16.3;U-937: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049771, HPA075115" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA049771: AB_2680872, HPA075115: " "unprognostic (9.71e-3)" "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (4.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.50e-2)" "unprognostic (2.88e-2)" "unprognostic (5.72e-4)" "unprognostic (5.46e-2)" "unprognostic (3.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.91e-1)" "unprognostic (1.61e-2)" "unprognostic (4.27e-3)" "unprognostic (9.99e-2)" "unprognostic (7.76e-2)" "unprognostic (4.37e-4)" 4.7 1.3 8.1 3.0 9.6 2.2 3.2 11.8 6.6 3.2 12.3 4.9 0.8 3.2 1.4 3.1 2.3 4.3 2.2 6.6 5.9 1.1 0.9 3.4 0.8 1.5 9.1 1.6 0.6 1.6 2.6 2.2 4.6 3.5 1.9 0.3 1.5 4.8 0.8 1.4 1.7 6.9 0.8 2.8 1.9 2.4 6.9 1.0 2.7 2.4 0.9 3.7 2.3 0.0 0.4 0.6 25.2 0.1 0.3 1.0 0.2 0.9 4.7 0.1 0.4 0.1 0.0 0.2 29.5 2.6 0.1 0.0 1.6 0.0 0.6 0.1 0.6 0.1 0.1 0.0 0.1 0.1 1.4 0.5 0.0 0.9 0.0 0.1 27.8 0.1 0.0 4.1 0.2 0.2 0.1 2.1 4.8 0.0 0.0 0.1 1.4 0.0 0.1 2.9 0.6 5.7 0.0 0.0 0.0 7.1 0.1 1.7 16.3 0.0 1.6 2.0 0.0 0.1 0.0 0.1 1.1 20.5 0.0 5.0 7.1 14.3 2.0 4.7 1.9 0.0 1.0 1.7 4.1 0.0 0.1 0.2 15.6 1.0 3.7 0.0 0.1 2.3 8.1 9.6 11.8 6.6 6.6 5.9 1.5 9.1 4.6 0.8 6.9 0.0 29.2 0.0 1.9 1.0 7.3 0.5 101.2 0.0 0.6 0.9 5.0 3.7 19.6 21.5 0.0 1.8 0.0 17.9 10.1 2.0 0.0 0.2 4.7 3.3 2.8 32.9 1.2 17.3 7.8 0.7 24.3 15.2 0.5 9.0 7.6 0.9 51.0 19.0 19.1 0.0 5.8 3.7 0.0 49.0 0.5 7.4 31.7 19.7 1.8 19.7 57.7 1.5 32.0 5.5 1.1 0.6 3.1 21.4 2.8 90.5 7.8 2.9 0.0 0.5 26.3 39.7 12.6 2.7 3.7 0.3 0.3 24.9 17.0 2.9 3.8 80.7 NKD1 ENSG00000140807 "NKD inhibitor of WNT signaling pathway 1" Q969G9 16 50548396-50649249 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.6" "Cell type enhanced" "Detected in many" "Microglial cells: 45.9;Oligodendrocyte precursor cells: 57.3;Oligodendrocytes: 27.4;Smooth muscle cells: 13.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;CACO-2: 13.6;Hep G2: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041352, HPA049413" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli fibrillar center" "HPA041352: AB_2677428, HPA049413: AB_2680753" "unprognostic (1.58e-3)" "unprognostic (1.24e-2)" "unprognostic (1.94e-1)" "unprognostic (6.02e-3)" "unprognostic (5.59e-3)" "unprognostic (9.80e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (5.25e-3)" "unprognostic (2.29e-2)" "unprognostic (2.32e-2)" "unprognostic (1.87e-1)" "unprognostic (6.88e-4)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (3.30e-2)" "unprognostic (3.44e-2)" 1.7 0.7 7.3 0.7 7.9 0.1 1.0 7.1 4.6 2.5 2.1 4.8 1.1 6.0 4.2 3.2 4.7 2.8 0.5 4.0 5.5 1.6 0.6 6.8 0.4 9.3 12.8 2.9 1.2 0.2 0.4 1.9 7.2 3.5 1.4 0.7 0.5 2.7 0.3 2.0 2.0 5.7 7.0 1.5 2.1 1.1 14.6 0.7 0.3 0.2 0.5 2.2 1.2 7.7 0.0 0.1 6.3 0.5 2.4 0.0 0.2 0.0 0.0 0.0 0.0 13.6 0.3 0.0 0.2 0.0 0.1 0.0 2.2 0.1 0.0 0.0 0.7 0.7 0.0 36.5 0.0 0.3 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.1 1.4 0.5 0.6 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 7.9 7.1 4.6 4.0 5.5 9.3 12.8 7.2 7.0 14.6 7.7 0.3 0.0 0.0 4.2 0.2 1.5 1.2 0.2 0.0 2.1 0.3 0.8 0.8 0.0 0.5 0.0 6.2 2.5 0.7 0.2 0.0 0.4 7.4 0.5 2.0 0.9 1.8 0.4 0.4 0.4 0.4 3.8 1.5 0.7 0.0 3.7 0.4 1.7 0.4 0.0 1.0 0.5 0.0 0.0 3.0 2.2 1.8 0.8 8.8 45.9 0.2 6.7 0.0 57.3 27.4 0.3 0.0 3.4 0.5 0.9 0.2 0.1 0.1 0.8 13.1 0.4 13.4 1.1 7.1 0.6 1.1 2.3 2.4 0.0 0.5 1.4 NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 68.3;brain: 58.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 319.5;Club cells: 164.2;Ductal cells: 123.9" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 90.1" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.0" "Group enriched" "Detected in all" 5 "olfactory bulb: 43.3;pons: 14.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" 68.3 24.0 19.9 4.1 17.9 6.0 30.7 18.2 23.5 8.3 16.3 5.3 3.1 7.5 4.9 6.9 8.6 4.8 5.4 21.4 58.9 10.7 3.1 6.2 5.7 29.3 22.7 7.1 8.4 4.5 9.8 1.9 26.2 5.0 2.9 3.0 7.4 2.5 2.5 4.9 4.1 4.7 22.4 4.8 5.5 11.9 21.4 4.5 17.7 3.1 3.0 8.5 6.5 44.7 90.1 35.3 6.1 1.3 17.1 7.7 0.8 4.7 10.5 12.5 16.6 12.9 23.5 3.4 12.9 14.7 0.1 15.0 34.0 7.0 7.4 30.3 36.7 12.4 13.2 59.7 4.4 8.2 13.6 7.6 2.8 18.2 7.2 7.6 17.9 23.3 0.2 1.4 6.9 55.2 8.8 30.0 22.9 18.0 8.9 25.7 0.1 38.7 11.5 7.3 3.1 34.6 8.2 5.1 40.5 6.0 5.9 33.8 4.0 2.4 10.3 10.3 7.9 0.7 9.9 8.2 26.3 52.9 14.1 0.0 1.0 7.8 7.9 0.7 2.9 5.9 5.9 7.7 4.5 11.3 5.8 4.1 1.6 1.8 0.5 13.4 7.6 3.4 19.9 17.9 18.2 23.5 21.4 58.9 29.3 22.7 26.2 22.4 21.4 44.7 39.0 3.2 2.7 5.5 13.6 15.6 29.5 319.5 21.6 1.9 30.7 37.6 3.5 20.0 164.2 31.3 0.0 2.4 25.3 5.3 13.7 123.9 33.7 21.3 7.3 19.6 18.6 7.4 0.6 58.2 14.1 19.7 11.2 15.6 5.7 12.0 7.5 3.7 32.3 5.0 1.2 6.5 18.3 8.8 86.4 29.0 4.4 26.0 33.8 1.9 18.5 6.5 25.7 2.0 1.0 45.2 5.1 3.8 32.5 39.3 0.8 32.0 57.8 4.1 13.1 22.5 28.6 24.0 21.6 29.5 12.8 3.1 19.7 8.2 9.1 60.6 NOG "SYM1, SYNS1" ENSG00000183691 Noggin Q13253 17 56593699-56595611 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2;placenta: 10.6" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 72.8;naive CD8 T-cell: 34.9" "Lineage enriched" "Detected in single" 78 "T-cells: 72.8" "Cell line enhanced" "Detected in many" "EFO-21: 123.3;LHCN-M2: 38.1;NB-4: 28.8;PC-3: 37.9;U-2 OS: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061318 Approved "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 32: Non-specific - Translation" "HPA061318: AB_2684478" "unprognostic (1.49e-1)" "unprognostic (1.17e-2)" "unprognostic (1.49e-5)" "prognostic favorable (6.66e-4)" "unprognostic (4.69e-2)" "unprognostic (5.23e-3)" "unprognostic (1.26e-2)" "unprognostic (3.06e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (6.86e-5)" "unprognostic (2.88e-1)" "unprognostic (1.14e-6)" "unprognostic (8.39e-2)" "unprognostic (1.40e-1)" "unprognostic (5.00e-1)" "unprognostic (1.65e-1)" 0.7 0.1 6.1 0.6 4.8 0.2 0.3 1.7 4.2 4.7 0.3 0.3 0.1 0.3 0.1 0.2 0.5 0.0 0.5 4.0 3.6 0.4 0.1 0.7 1.8 2.1 5.0 0.0 0.1 0.0 0.7 10.6 1.8 0.8 0.0 0.0 0.3 1.4 3.5 0.3 0.5 0.1 2.4 0.7 0.9 0.7 8.2 0.6 0.4 0.8 0.4 0.8 2.7 2.0 6.3 0.2 0.2 0.0 0.2 0.0 0.0 3.2 3.5 1.2 1.3 0.4 1.2 0.0 123.3 1.5 4.8 0.5 2.2 0.3 3.4 0.1 2.2 0.0 5.2 0.0 0.0 0.9 0.0 0.5 0.7 0.0 0.5 0.4 0.1 0.1 0.0 0.0 38.1 0.2 1.1 28.8 2.6 0.0 37.9 17.0 11.6 0.0 2.9 0.0 0.2 0.0 6.5 0.1 0.0 9.9 0.1 0.5 0.7 2.3 38.5 0.2 2.7 0.0 0.1 0.4 0.0 3.2 0.0 0.9 0.1 0.2 0.6 0.2 0.2 0.1 4.3 0.5 0.1 0.1 72.8 34.9 0.8 0.4 0.3 0.3 3.4 3.1 6.1 4.8 1.7 4.2 4.0 3.6 2.1 5.0 1.8 2.4 8.2 2.0 0.4 0.0 0.0 2.0 0.3 0.0 0.4 0.0 0.6 0.0 0.1 0.9 1.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.5 0.1 0.6 1.5 0.3 0.0 2.5 0.2 0.0 12.2 1.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 1.0 1.5 0.1 0.6 0.0 0.0 0.3 0.3 0.0 0.4 0.0 0.0 0.0 2.3 0.4 0.0 1.7 0.4 0.1 0.8 2.0 0.0 0.0 0.1 NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.9;parathyroid gland: 81.0" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Endothelial cells: 115.3;Excitatory neurons: 71.9;Extravillous trophoblasts: 64.7;Hepatic stellate cells: 160.3" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 7 "granulocytes: 2.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 140.0;ASC TERT1: 107.6;fHDF/TERT166: 147.5;JURKAT: 134.8;REH: 196.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" 66.4 5.1 49.1 6.4 44.9 0.5 64.2 46.0 80.8 16.2 17.0 21.3 3.7 9.4 4.0 8.2 13.6 11.2 19.7 98.9 27.7 8.2 4.4 15.6 9.6 30.4 29.9 4.7 2.9 81.0 12.3 42.1 32.5 10.1 4.7 23.4 8.7 7.4 17.3 18.8 10.8 10.5 22.1 15.7 10.3 0.6 60.1 3.6 9.4 16.1 3.5 13.8 17.0 45.9 16.7 0.6 1.4 0.1 140.0 107.6 19.1 2.6 0.0 11.8 16.1 0.2 0.1 0.0 2.5 147.5 25.0 0.5 43.3 0.0 11.4 26.1 21.2 13.7 0.0 0.0 0.0 58.0 43.7 17.3 0.0 10.5 0.0 0.1 57.4 134.8 0.2 0.6 42.5 0.1 89.7 2.6 0.1 0.0 0.0 196.3 47.7 0.4 0.2 0.2 24.9 9.2 0.0 0.8 13.9 0.2 0.4 16.4 12.1 56.4 1.6 21.4 36.5 0.1 2.2 0.9 85.8 0.2 8.9 0.0 0.1 0.0 0.1 0.1 2.6 0.3 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 0.1 49.1 44.9 46.0 80.8 98.9 27.7 30.4 29.9 32.5 22.1 60.1 45.9 262.9 0.0 1.3 7.2 1.6 10.5 0.1 0.0 1.2 6.7 1.4 2.4 2.5 1.5 0.0 0.0 2.1 1.5 1.0 0.0 0.0 0.1 0.1 0.0 0.1 115.3 0.0 0.0 71.9 0.5 64.7 15.9 0.0 0.1 0.0 0.0 160.3 0.9 1.8 3.3 3.0 0.0 0.0 4.1 21.5 0.4 0.9 1.4 16.0 8.4 0.5 4.5 0.0 13.6 8.3 0.2 0.0 0.0 1.4 0.4 0.0 0.0 0.0 20.2 0.0 4.4 18.3 0.4 0.3 0.6 11.2 1.4 1.9 0.1 0.0 0.7 NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708836-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 11.2;intestine: 11.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.4;Cardiomyocytes: 1.1;Excitatory neurons: 1.6;Inhibitory neurons: 1.3;Kupffer cells: 2.9;Microglial cells: 1.0;monocytes: 1.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.9" "Region enriched" "Detected in many" 7 "midbrain: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "PC-3: 57.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050299 Supported "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA050299: " "unprognostic (4.14e-2)" "unprognostic (2.02e-2)" "unprognostic (2.75e-2)" "unprognostic (8.87e-4)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.17e-2)" "unprognostic (2.80e-3)" "unprognostic (7.16e-2)" "unprognostic (3.10e-3)" "unprognostic (3.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" 0.0 0.0 1.1 0.0 1.5 0.6 0.0 0.0 1.4 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 2.0 10.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 2.8 0.2 2.7 0.3 1.1 57.7 1.8 0.0 9.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.5 0.0 1.4 1.4 0.4 0.4 11.2 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 4.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.9 0.3 0.0 0.0 0.5 0.0 1.0 1.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.6;lung: 100.2;placenta: 114.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 399.0;Hofbauer cells: 202.1;Macrophages: 202.6;Syncytiotrophoblasts: 463.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 125.4;HaCaT: 64.9;HHSteC: 125.1;hTCEpi: 58.4;SiHa: 248.8;SK-BR-3: 96.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1060000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" 3.0 3.3 9.0 29.1 13.1 23.8 3.6 18.9 16.9 3.3 8.8 0.7 1.3 1.6 1.3 0.5 2.1 7.4 1.5 9.4 13.3 8.2 3.1 100.2 0.7 25.5 15.6 0.3 2.2 4.1 2.7 114.5 26.0 2.3 1.0 5.1 3.8 1.0 0.5 0.6 1.2 2.1 27.6 0.8 2.3 4.7 24.0 2.8 2.5 0.0 0.8 6.0 0.3 52.6 7.3 0.5 0.1 0.3 0.3 0.0 16.8 12.1 2.2 7.3 2.6 125.4 0.1 1.6 0.0 15.8 0.5 64.9 0.0 0.7 4.9 0.0 0.0 0.0 6.1 0.0 125.1 0.1 0.3 1.0 58.4 0.3 0.0 0.0 0.3 0.1 0.1 0.7 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.3 0.2 13.3 0.4 0.2 248.8 96.9 0.0 17.4 27.1 0.0 0.1 0.2 1.4 0.0 0.0 0.4 0.3 0.4 0.1 0.1 0.1 0.6 0.6 1.3 0.1 0.1 0.1 0.1 0.1 0.0 2.8 0.2 0.1 0.1 1.4 0.1 0.1 0.3 0.1 0.6 9.0 13.1 18.9 16.9 9.4 13.3 25.5 15.6 26.0 27.6 24.0 52.6 1.9 28.9 27.4 0.0 4.0 1.5 0.4 0.5 0.0 0.4 1.1 4.6 0.1 1.5 4.4 0.0 0.0 399.0 0.3 0.0 0.0 0.1 13.4 0.1 0.0 10.8 0.0 0.4 2.3 0.0 14.6 10.9 0.5 0.1 15.2 0.0 0.0 0.5 202.1 0.0 0.2 0.0 0.0 18.9 79.5 11.6 0.3 202.6 0.0 40.3 21.3 0.1 0.0 0.5 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.2 6.6 0.2 0.0 0.2 0.4 0.1 0.2 0.8 0.6 463.1 1.6 0.1 0.0 0.3 OPN3 "ECPN, encephalopsin, ERO, NMO-1, PPP1R116" ENSG00000054277 "Opsin 3" Q9H1Y3 1 241590102-241677376 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 18.7" "Cell type enhanced" "Detected in many" "Early spermatids: 133.9;Extravillous trophoblasts: 252.9;Langerhans cells: 206.8;Syncytiotrophoblasts: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 10.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 72.4" "Low region specificity" "Detected in all" "CAB013682, HPA064443" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB013682: , HPA064443: AB_2685267" "unprognostic (2.41e-2)" "prognostic unfavorable (3.17e-5)" "unprognostic (1.75e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (7.12e-2)" "unprognostic (5.10e-3)" "unprognostic (1.24e-2)" "unprognostic (2.39e-1)" "unprognostic (4.96e-1)" "unprognostic (2.66e-2)" "unprognostic (3.44e-1)" "unprognostic (9.13e-2)" "unprognostic (9.15e-3)" "unprognostic (2.61e-2)" "unprognostic (7.12e-2)" "unprognostic (9.44e-3)" 2.6 2.2 5.0 3.4 5.5 1.1 3.1 4.1 9.6 2.7 3.2 6.4 1.6 3.8 4.4 4.2 4.5 3.1 2.1 5.8 4.3 4.2 11.0 8.4 4.4 3.5 6.4 2.1 1.9 1.4 2.7 18.7 3.4 1.0 5.5 0.5 2.3 1.3 1.8 2.2 2.9 1.8 3.5 4.5 3.3 2.5 7.1 4.9 3.2 4.0 5.1 4.2 2.9 5.3 4.5 15.0 10.7 0.8 38.3 72.4 8.2 8.0 6.0 5.6 5.6 1.1 12.5 0.6 0.4 9.7 6.3 25.9 3.4 5.7 5.6 16.7 0.8 0.0 3.2 9.5 19.4 3.9 8.3 37.0 15.5 3.5 8.4 37.7 11.5 13.4 7.6 2.3 9.1 2.4 1.4 5.0 29.1 19.3 8.0 6.3 0.6 14.6 38.5 6.7 2.8 10.9 5.0 15.6 4.6 21.5 0.8 14.9 13.9 1.3 1.0 2.2 8.6 5.3 8.7 0.7 4.3 12.4 16.7 0.0 0.8 0.7 0.0 1.1 0.0 1.8 0.1 0.1 2.2 1.7 0.2 0.3 0.3 0.5 1.1 10.0 0.2 0.5 5.0 5.5 4.1 9.6 5.8 4.3 3.5 6.4 3.4 3.5 7.1 5.3 3.7 6.4 5.4 4.9 35.5 14.7 13.5 12.7 18.8 3.3 12.4 10.5 0.8 15.7 7.0 12.9 0.0 80.6 60.1 41.4 13.7 16.8 133.9 10.5 5.8 5.9 4.2 15.1 56.7 10.5 252.9 7.7 12.8 22.2 2.5 22.4 8.6 26.3 26.6 0.0 15.7 8.8 20.3 31.9 206.8 89.7 11.1 56.9 28.4 9.4 30.2 4.3 5.2 10.1 7.2 19.3 10.8 16.6 18.4 20.1 7.6 21.5 2.7 2.1 0.0 5.4 13.3 7.8 8.3 29.7 12.4 171.6 6.4 6.6 7.1 15.2 OSBPL5 "KIAA1534, OBPH1, ORP5" ENSG00000021762 "Oxysterol binding protein like 5" Q9H0X9 11 3087107-3166739 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 34.6;Horizontal cells: 62.2;NK-cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 3.6;gdT-cell: 9.0;intermediate monocyte: 4.7;memory CD8 T-cell: 3.3;myeloid DC: 3.0;naive CD8 T-cell: 3.4;NK-cell: 11.0;non-classical monocyte: 11.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038335, HPA038712, HPA058727" Approved Enhanced Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA038335: AB_2675963, HPA038712: AB_10675949, HPA058727: AB_2683799" "unprognostic (6.02e-2)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (3.69e-2)" "unprognostic (8.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (4.03e-3)" "unprognostic (1.29e-1)" "unprognostic (3.49e-3)" "unprognostic (2.16e-3)" "unprognostic (9.44e-2)" "unprognostic (2.78e-2)" "unprognostic (1.22e-1)" "unprognostic (6.50e-2)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" 22.0 8.0 7.1 7.2 7.7 13.6 19.2 7.8 11.5 42.2 2.1 28.2 5.9 26.6 2.9 12.5 22.3 5.0 14.9 5.2 6.4 13.5 3.1 17.5 2.4 50.3 13.3 14.5 10.4 2.3 10.3 5.0 56.0 25.6 3.2 1.8 16.4 9.9 9.9 25.9 16.6 7.6 5.4 24.9 15.5 3.3 19.8 22.0 14.9 5.9 1.4 24.6 28.3 10.5 3.7 5.6 6.6 7.6 18.9 8.8 0.1 17.9 8.8 7.1 5.0 0.0 10.4 0.0 5.3 10.1 4.9 13.3 1.3 5.0 1.1 3.5 6.0 15.1 19.2 0.0 15.9 13.6 2.3 13.9 5.7 2.5 2.6 5.2 4.8 26.7 5.5 0.0 3.5 10.3 30.7 75.5 4.8 2.4 11.5 15.9 9.0 2.2 3.0 3.3 10.8 1.3 7.6 26.1 7.0 3.7 10.8 35.9 16.4 8.8 12.1 21.2 3.1 3.8 0.0 0.5 9.5 25.3 11.5 0.2 3.6 1.2 9.0 4.7 1.2 0.0 0.9 3.3 3.0 0.0 0.6 3.4 0.4 11.0 11.5 1.3 0.1 5.2 7.1 7.7 7.8 11.5 5.2 6.4 50.3 13.3 56.0 5.4 19.8 10.5 19.5 0.0 5.5 8.1 0.5 4.8 2.6 4.2 5.2 11.5 7.7 5.2 6.9 2.8 4.8 3.7 8.4 0.4 34.6 8.3 1.9 3.0 0.1 2.2 22.1 12.1 0.0 5.7 25.6 2.0 0.6 12.3 5.1 2.5 1.3 3.5 3.9 0.5 1.7 62.2 20.6 8.0 2.0 8.7 3.1 1.2 9.0 3.9 3.6 17.8 2.3 4.1 56.7 20.1 28.2 2.2 8.5 17.0 4.9 3.2 6.1 3.2 5.5 1.2 13.1 7.4 11.4 0.1 0.6 3.8 6.8 0.0 9.1 2.5 8.2 2.5 OXTR ENSG00000180914 "Oxytocin receptor" P30559 3 8750381-8769628 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 14.7;breast: 54.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 122.6;Excitatory neurons: 25.8;Oligodendrocyte precursor cells: 21.1;Respiratory ciliated cells: 57.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 421.2;BJ hTERT+: 127.9;BJ hTERT+ SV40 Large T+: 119.4;fHDF/TERT166: 424.5;HBF TERT88: 92.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.18e-1)" "unprognostic (7.94e-2)" "unprognostic (4.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (2.02e-1)" "unprognostic (1.46e-2)" "unprognostic (2.56e-3)" "unprognostic (2.12e-1)" "unprognostic (3.42e-1)" "unprognostic (2.76e-1)" "unprognostic (3.80e-2)" "unprognostic (4.24e-4)" "unprognostic (8.25e-2)" "unprognostic (4.60e-2)" "unprognostic (2.71e-1)" "unprognostic (1.84e-1)" 0.4 0.2 4.0 0.1 8.1 0.6 54.1 3.3 4.1 0.5 0.3 0.2 0.1 3.5 0.3 1.6 3.0 0.3 0.5 3.1 13.7 0.5 0.2 0.9 0.2 14.7 12.4 3.1 0.1 0.1 0.3 0.5 6.6 0.8 0.1 2.7 0.2 0.8 0.2 0.2 0.2 0.5 12.0 0.3 0.2 0.3 13.7 0.3 0.3 0.1 0.1 0.8 0.2 3.7 1.1 4.6 2.5 0.5 0.5 1.2 0.8 421.2 127.9 119.4 63.4 0.6 11.3 0.3 0.9 424.5 1.7 0.9 2.0 0.9 92.4 3.9 2.1 1.1 1.9 0.7 2.2 1.0 1.0 0.7 0.5 1.7 0.9 36.1 0.2 1.3 0.2 0.8 67.5 0.3 0.9 3.3 2.7 1.4 18.7 0.9 1.6 25.5 4.5 0.4 0.7 0.8 0.7 0.9 0.2 8.1 0.3 0.6 0.6 5.9 1.5 1.2 1.2 0.7 1.2 0.2 0.6 1.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.0 8.1 3.3 4.1 3.1 13.7 14.7 12.4 6.6 12.0 13.7 3.7 1.3 9.6 1.1 3.3 0.3 0.4 0.6 1.0 0.0 0.8 2.3 122.6 1.5 1.5 6.5 0.0 0.0 0.2 0.4 0.3 0.0 2.7 1.4 4.7 0.6 0.7 0.0 0.0 25.8 0.0 0.1 2.0 0.0 0.9 0.0 4.3 1.4 0.0 0.2 0.0 14.0 0.0 2.0 0.0 0.0 2.0 0.0 3.1 0.0 5.6 0.1 7.9 0.0 21.1 15.4 1.2 0.1 0.4 0.2 2.2 0.0 0.1 57.1 0.2 0.0 2.0 16.9 1.0 1.8 0.0 0.1 0.0 0.3 3.1 0.1 0.3 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PARD3B "ALS2CR19, PAR3beta, Par3L" ENSG00000116117 "Par-3 family cell polarity regulator beta" Q8TEW8 2 204545475-205620162 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 490.7;Microglial cells: 183.6;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 17.8;BJ hTERT+: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035283 Approved Supported "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions" "HPA035283: AB_10671102" "unprognostic (6.18e-2)" "unprognostic (3.86e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.61e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (2.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.67e-10)" "unprognostic (1.74e-1)" "unprognostic (8.13e-2)" "unprognostic (1.23e-1)" "unprognostic (8.09e-2)" 9.1 2.8 6.0 1.7 7.3 0.0 5.5 5.3 5.3 4.9 9.3 12.6 3.6 5.1 3.7 4.0 6.5 4.5 4.0 4.6 9.2 6.9 3.4 5.4 2.1 9.3 12.2 7.3 4.9 9.2 1.9 4.4 8.3 4.8 5.5 2.5 3.0 5.2 2.7 4.5 4.2 5.2 8.4 3.1 4.5 3.8 8.0 1.4 5.6 3.6 2.5 5.9 4.0 7.4 2.5 2.1 6.3 2.3 17.8 8.9 3.4 3.8 12.5 3.5 3.8 6.2 1.7 0.0 4.3 7.8 2.8 0.3 0.8 1.0 3.6 0.2 2.9 8.8 5.2 0.0 1.8 0.0 0.5 3.4 1.7 1.2 5.2 5.3 5.2 0.8 0.2 0.1 4.5 1.0 0.0 0.0 0.8 0.9 0.5 0.0 2.7 2.1 3.7 2.5 0.7 2.0 2.0 1.9 1.7 6.2 3.1 0.0 10.9 2.7 1.7 5.5 1.8 0.0 0.0 0.0 2.6 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 7.3 5.3 5.3 4.6 9.2 9.3 12.2 8.3 8.4 8.0 7.4 9.5 9.6 8.6 490.7 0.5 11.0 3.3 2.4 6.8 0.5 5.6 5.8 10.8 15.7 14.5 29.5 0.0 3.2 0.2 12.4 0.0 8.7 76.6 8.5 4.0 6.8 6.0 0.8 5.6 2.4 0.2 16.2 11.7 7.4 1.3 14.1 8.2 4.5 0.5 5.0 50.8 9.2 2.0 1.0 4.3 26.0 31.1 0.6 7.2 183.6 0.1 9.7 0.0 159.3 104.2 6.5 15.9 57.9 1.4 5.0 9.4 4.8 17.0 0.3 19.7 23.5 9.6 1.4 2.9 3.5 4.7 1.1 1.0 2.3 8.0 5.3 PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Bipolar cells: 3.8;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.3;Endothelial cells: 2.2;Fibroblasts: 3.2;Skeletal myocytes: 2.0" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in some" "BJ: 9.3;BJ hTERT+: 15.4;fHDF/TERT166: 23.3;HHSteC: 7.2;HSkMC: 16.5;TIME: 7.5" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" 3.0 4.3 5.3 0.8 6.8 0.0 1.5 5.5 3.7 2.0 0.8 1.3 0.2 2.6 0.4 1.0 1.9 3.9 4.2 5.1 8.4 1.0 0.7 3.1 0.4 10.0 4.2 1.9 1.1 0.3 1.4 2.2 4.5 1.0 0.3 1.4 0.9 1.5 1.3 1.7 0.8 1.7 5.5 1.2 1.0 0.3 5.2 0.9 1.6 1.1 0.4 1.2 2.0 4.6 0.0 0.0 0.1 1.9 0.8 1.4 0.1 9.3 15.4 0.0 0.0 0.0 0.0 0.5 0.0 23.3 0.1 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 4.5 0.0 0.0 5.4 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 2.6 7.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 6.8 5.5 3.7 5.1 8.4 10.0 4.2 4.5 5.5 5.2 4.6 2.2 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 3.8 0.2 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.3 2.2 0.0 0.0 0.0 0.2 0.0 3.2 1.1 0.1 0.0 0.1 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.7 0.0 2.0 1.0 0.0 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.4;Cardiomyocytes: 1.6;Endometrial stromal cells: 1.9;Fibroblasts: 1.3;Horizontal cells: 3.3;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 7.1;BJ: 2.3;EFO-21: 5.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.47e-2)" "unprognostic (4.79e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.85e-1)" "unprognostic (7.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.32e-3)" "unprognostic (7.12e-3)" "unprognostic (3.31e-2)" "unprognostic (2.52e-4)" 1.2 1.2 2.6 0.2 1.7 0.0 0.9 2.2 2.6 1.6 0.1 0.7 0.0 1.4 0.9 0.2 1.2 0.9 3.7 2.5 1.8 0.5 0.6 0.9 0.0 3.8 2.9 2.5 0.9 0.6 1.2 1.7 2.2 0.7 0.2 1.8 0.7 0.8 0.8 0.5 0.2 0.9 3.4 0.2 0.4 1.5 2.9 0.2 0.8 0.9 0.1 0.8 0.9 2.5 0.0 0.0 7.1 0.0 0.0 0.9 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 5.7 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 2.2 2.6 2.5 1.8 3.8 2.9 2.2 3.4 2.9 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.1 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.9 0.1 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Bipolar cells: 8.4;Endometrial stromal cells: 5.5;Fibroblasts: 10.2;Horizontal cells: 11.8;Skeletal myocytes: 6.6" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Cell line enhanced" "Detected in many" "ASC diff: 200.7;HSkMC: 186.2;U-138 MG: 244.1;WM-115: 382.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" 63.3 64.3 248.0 15.4 241.0 0.2 59.9 221.6 308.1 107.8 165.1 60.4 7.4 81.3 60.8 54.5 62.6 30.2 77.8 232.3 227.5 36.6 29.5 101.9 9.5 236.9 241.0 65.1 34.7 36.8 79.0 37.1 216.6 66.0 20.4 36.3 46.4 40.7 27.6 64.7 32.0 39.5 216.5 22.2 38.7 22.0 263.5 15.7 45.7 26.3 14.8 60.6 80.0 220.8 12.8 7.7 48.1 14.0 200.7 178.3 0.6 58.6 162.6 30.9 32.5 0.0 12.7 43.5 39.7 108.0 111.7 46.2 6.1 20.7 28.2 0.2 20.0 0.1 1.2 1.2 62.6 0.5 1.5 186.2 31.6 46.9 37.2 104.2 19.7 0.0 0.2 1.6 79.2 24.8 1.0 5.4 2.3 0.8 0.1 30.0 97.1 0.4 17.9 13.7 16.6 69.8 17.3 0.6 115.9 16.8 40.0 66.9 22.1 244.1 12.2 46.7 72.2 0.1 0.6 0.7 60.3 0.1 382.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.1 248.0 241.0 221.6 308.1 232.3 227.5 236.9 241.0 216.6 216.5 263.5 220.8 2.5 0.0 0.0 0.0 0.3 0.3 0.5 0.3 8.0 8.4 0.2 1.1 0.8 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.2 1.4 0.3 5.5 1.9 0.0 0.0 0.0 0.2 0.2 10.2 0.0 0.5 0.0 0.2 1.1 0.0 0.3 11.8 0.0 0.2 0.0 0.3 0.3 0.7 1.2 0.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.6 0.0 0.1 0.0 1.0 0.0 6.6 1.7 1.6 0.0 3.9 0.1 0.7 0.1 3.5 0.0 0.5 PEDS1 "CarF, Kua, TMEM189" ENSG00000240849 "Plasmanylethanolamine desaturase 1" A5PLL7 20 50118254-50153734 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 86.8;Extravillous trophoblasts: 167.6;Hofbauer cells: 38.6;Syncytiotrophoblasts: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059549 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA059549: AB_2684059" "unprognostic (3.11e-2)" "unprognostic (7.04e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (2.03e-3)" "unprognostic (7.00e-2)" "unprognostic (2.19e-2)" "unprognostic (1.35e-1)" "unprognostic (8.63e-2)" "unprognostic (5.79e-2)" "prognostic unfavorable (5.79e-11)" "unprognostic (1.85e-1)" "unprognostic (1.20e-1)" "unprognostic (9.46e-2)" "unprognostic (4.42e-2)" 13.2 14.0 19.6 7.3 24.0 5.7 10.4 25.3 24.3 12.7 15.8 18.4 8.7 13.8 10.7 26.0 9.1 7.2 20.8 19.6 20.8 9.3 17.8 13.7 6.0 25.8 24.4 5.5 9.3 12.8 5.8 17.6 24.1 11.6 7.1 2.2 12.4 13.5 16.9 22.9 9.8 21.8 21.0 10.0 15.1 6.3 23.3 7.8 7.7 16.3 7.4 15.4 15.1 29.1 19.6 17.7 20.7 16.3 30.7 23.0 34.6 13.6 12.6 27.8 15.6 48.6 30.5 7.2 21.2 12.8 39.7 52.8 10.4 27.4 10.0 3.8 8.0 9.3 24.5 41.6 17.3 15.1 24.2 19.7 62.7 15.6 16.4 13.4 33.6 12.2 9.8 10.2 9.5 17.3 12.0 38.1 10.1 50.1 18.3 9.7 15.9 7.8 53.7 28.4 10.8 7.1 15.4 52.2 32.4 20.3 8.3 21.2 26.8 23.1 12.1 15.1 13.5 7.5 13.6 2.9 19.9 11.1 19.1 4.9 5.3 6.2 3.1 10.2 2.6 1.8 3.5 2.6 5.6 1.5 2.9 3.4 2.0 4.0 14.0 3.6 5.6 3.8 19.6 24.0 25.3 24.3 19.6 20.8 25.8 24.4 24.1 21.0 23.3 29.1 8.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 86.8 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 167.6 6.3 0.0 0.0 0.0 0.0 0.0 0.0 38.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 50.1 1.2 0.0 0.0 0.0 PHLDA3 TIH1 ENSG00000174307 "Pleckstrin homology like domain family A member 3" Q9Y5J5 1 201464278-201469237 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 269.3;Prostatic glandular cells: 188.7;Urothelial cells: 556.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 284.8;WM-115: 164.3" "Low region specificity" "Detected in all" HPA027601 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "HPA027601: AB_10601389" "unprognostic (1.51e-1)" "unprognostic (7.48e-2)" "unprognostic (5.65e-2)" "prognostic favorable (1.77e-4)" "unprognostic (8.55e-3)" "unprognostic (4.34e-3)" "unprognostic (5.55e-3)" "unprognostic (1.42e-1)" "unprognostic (2.16e-3)" "unprognostic (8.65e-2)" "unprognostic (8.78e-2)" "unprognostic (7.65e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (9.32e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (7.45e-2)" 155.6 30.0 34.9 8.4 50.6 0.3 119.3 51.2 41.9 56.8 21.3 139.4 4.1 52.9 11.6 89.4 40.8 15.3 40.9 31.7 39.4 18.2 8.1 41.6 2.5 73.4 50.3 23.5 23.4 10.7 28.4 8.9 51.3 64.8 5.5 3.0 39.3 26.8 75.9 68.3 29.0 17.8 45.2 10.4 35.1 8.9 52.1 10.1 31.5 11.6 4.9 75.5 68.4 69.2 52.4 60.8 11.1 33.5 50.6 47.7 284.8 75.6 57.3 18.2 21.0 4.0 39.5 0.1 3.1 37.6 15.7 90.0 1.0 61.0 3.6 0.0 22.4 0.0 26.2 47.6 57.4 0.0 1.0 66.7 90.6 29.4 25.8 53.5 26.3 4.5 0.0 0.1 36.7 37.5 8.0 0.8 19.1 0.0 3.8 2.5 51.9 0.0 16.9 115.1 0.7 11.7 26.5 0.8 62.7 42.5 25.0 3.6 39.4 42.2 69.6 36.1 16.2 1.4 0.2 0.1 102.4 0.1 164.3 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.2 0.0 0.1 0.6 0.0 34.9 50.6 51.2 41.9 31.7 39.4 73.4 50.3 51.3 45.2 52.1 69.2 83.3 9.6 9.1 8.8 0.9 78.1 269.3 48.8 93.9 5.2 29.8 42.4 6.2 2.8 30.7 49.7 0.0 84.9 1.8 2.2 11.7 42.0 36.8 42.7 15.2 22.2 5.3 2.7 5.7 18.9 24.4 43.3 7.1 31.8 0.0 11.2 10.4 1.4 18.1 0.0 8.3 2.1 10.2 0.6 28.5 136.5 26.8 7.9 32.0 1.0 18.2 105.4 1.0 4.5 37.1 71.4 2.9 41.8 2.1 188.7 1.2 8.5 22.3 5.2 0.0 38.0 55.8 0.8 4.0 92.1 102.0 37.5 5.7 46.5 3.6 556.5 PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 87.2;Late spermatids: 87.7;Oligodendrocytes: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.2;ASC TERT1: 105.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "Plasma membrane" "HPA037959: AB_10673651, HPA038448: AB_10697390" "unprognostic (7.81e-2)" "unprognostic (8.32e-3)" "unprognostic (1.13e-1)" "unprognostic (9.36e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.37e-3)" "unprognostic (1.22e-1)" "unprognostic (3.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.36e-6)" "unprognostic (7.09e-2)" "unprognostic (2.42e-2)" "unprognostic (3.69e-2)" "unprognostic (1.44e-1)" 52.6 8.1 39.2 11.5 79.7 0.5 38.9 42.5 66.0 39.1 3.8 23.8 9.2 38.4 2.6 9.1 30.2 21.6 33.0 42.3 49.2 15.8 3.2 26.8 4.6 64.3 64.6 31.9 22.2 4.5 8.8 24.6 56.0 16.7 6.4 1.6 11.1 15.8 13.3 15.1 15.3 18.6 33.4 12.5 14.3 12.0 75.3 3.1 20.3 13.6 2.3 21.9 22.9 133.7 4.8 7.5 28.9 14.2 105.2 105.9 10.1 21.9 26.6 12.7 7.4 11.2 31.8 0.0 40.2 44.3 17.2 18.6 6.6 44.8 2.0 0.7 4.2 8.6 5.7 5.5 27.2 0.0 15.8 55.8 9.6 17.8 12.5 28.3 36.6 0.7 7.5 0.3 16.7 3.4 0.1 0.5 10.2 0.4 3.8 1.1 7.5 0.7 12.5 6.8 6.5 14.5 55.8 4.7 15.6 11.3 20.1 2.7 45.4 25.9 22.9 13.2 18.3 0.2 0.0 0.1 7.5 1.5 29.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 39.2 79.7 42.5 66.0 42.3 49.2 64.3 64.6 56.0 33.4 75.3 133.7 34.4 6.4 13.7 53.2 1.6 18.4 9.2 13.7 14.2 4.0 7.2 19.6 5.6 1.5 6.3 31.3 0.0 1.0 2.5 34.2 0.0 9.4 78.3 11.6 87.2 32.1 8.4 0.0 4.1 4.4 1.5 54.9 11.7 8.6 1.3 25.6 26.4 0.9 5.9 3.3 8.3 20.4 0.0 2.5 34.4 87.7 67.1 8.2 12.4 23.4 2.2 7.6 0.0 67.3 244.5 24.3 29.8 44.4 0.7 4.2 10.7 7.8 0.5 2.3 39.5 42.9 53.8 21.9 10.1 1.9 9.1 1.5 5.4 11.0 16.8 2.4 PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 500.3;Oligodendrocytes: 709.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 40000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019053: AB_1855361, HPA019061: AB_1855362" "unprognostic (9.27e-3)" "unprognostic (7.29e-2)" "unprognostic (3.51e-1)" "unprognostic (6.83e-2)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (5.36e-3)" "unprognostic (9.02e-3)" "unprognostic (9.80e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.31e-1)" "prognostic favorable (2.02e-6)" "unprognostic (1.26e-2)" "unprognostic (5.21e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" 183.5 62.5 97.1 120.4 162.1 111.4 111.5 119.3 118.7 86.4 43.8 86.3 106.3 79.3 52.4 109.1 66.1 127.0 87.9 91.7 110.8 168.5 147.0 99.4 82.7 125.2 130.7 94.4 80.6 120.6 36.5 157.2 131.6 73.1 83.1 71.5 62.3 93.6 75.8 74.2 115.5 135.3 106.0 126.5 73.0 64.9 120.7 93.1 75.7 101.9 96.7 139.5 73.5 194.7 167.0 78.4 121.1 85.9 185.5 188.8 228.5 211.7 274.7 164.4 143.0 310.7 222.4 126.0 210.8 342.6 171.1 134.6 129.4 154.2 232.8 38.6 45.0 364.9 101.5 98.9 185.6 87.2 158.3 166.6 161.7 308.7 253.3 275.1 178.7 85.9 239.1 103.0 305.2 98.2 103.9 76.8 66.9 269.0 42.7 69.8 182.2 91.1 312.5 139.2 72.9 58.7 258.4 85.4 68.7 156.5 115.6 67.0 196.9 298.6 104.1 355.0 170.2 36.7 107.1 118.4 70.8 64.6 206.6 6.4 13.5 7.5 5.7 11.7 4.9 3.1 4.2 8.0 11.4 2.1 4.2 4.0 40.6 7.1 12.5 3.9 6.4 5.3 97.1 162.1 119.3 118.7 91.7 110.8 125.2 130.7 131.6 106.0 120.7 194.7 147.1 35.3 58.9 134.5 33.3 116.0 44.4 33.0 30.1 20.8 34.8 28.6 46.4 42.9 34.3 71.7 12.5 42.9 43.9 64.2 31.3 57.7 59.3 32.3 32.8 98.7 25.1 88.8 144.7 37.6 127.1 44.6 34.1 50.9 48.2 23.2 71.4 52.3 85.0 40.4 140.7 30.1 30.5 142.8 229.2 95.4 35.8 127.4 60.5 500.3 92.1 22.6 32.0 188.0 709.3 90.2 55.3 43.6 39.1 49.5 71.4 84.0 41.0 16.3 78.9 36.4 92.7 17.3 14.1 34.4 96.5 41.3 38.9 23.6 30.6 77.7 PIGZ "FLJ12768, MGC52163, SMP3" ENSG00000119227 "Phosphatidylinositol glycan anchor biosynthesis class Z" Q86VD9 3 196946356-196969060 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 39.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 205.1;Intestinal goblet cells: 61.3;Paneth cells: 129.7;Proximal enterocytes: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA058599, HPA059920" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA058599: AB_2683771, HPA059920: AB_2684162" "unprognostic (1.46e-1)" "unprognostic (3.18e-3)" "unprognostic (1.06e-2)" "unprognostic (3.31e-2)" "unprognostic (3.90e-2)" "unprognostic (8.16e-2)" "unprognostic (4.25e-3)" "unprognostic (4.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (5.44e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (1.02e-1)" "unprognostic (3.93e-2)" "unprognostic (8.38e-5)" "unprognostic (5.02e-3)" 6.7 1.6 8.2 2.0 8.5 1.0 5.4 8.6 9.6 4.3 4.4 39.1 1.6 3.4 0.7 4.2 3.4 2.0 6.9 8.1 9.2 2.1 2.6 3.7 1.1 7.6 8.6 0.8 2.7 3.0 4.1 1.0 10.0 6.1 16.7 3.1 4.7 2.6 7.4 4.7 11.7 2.7 5.3 1.9 4.6 1.6 8.6 1.2 1.9 3.2 0.5 10.4 4.6 7.7 1.8 1.2 0.7 2.8 7.7 3.7 0.7 2.6 7.3 2.0 1.6 1.7 1.5 0.3 5.1 5.9 1.3 3.0 0.1 0.4 0.5 0.5 0.3 0.8 0.6 6.5 3.6 0.0 2.9 3.7 5.6 0.3 0.9 2.2 2.4 4.7 0.2 2.2 1.9 3.2 0.3 1.5 0.1 2.2 0.9 0.4 0.1 0.6 3.0 3.3 1.1 1.2 3.7 0.3 1.5 0.3 7.2 2.6 6.0 1.6 0.4 4.7 0.9 1.0 0.1 0.1 0.4 1.1 0.6 0.0 0.3 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 8.2 8.5 8.6 9.6 8.1 9.2 7.6 8.6 10.0 5.3 8.6 7.7 8.9 0.0 1.1 20.5 1.7 7.8 9.1 3.8 6.8 7.1 22.6 33.9 8.0 1.5 2.8 9.2 2.1 0.0 2.8 205.1 5.9 2.3 2.1 5.1 3.0 5.5 13.8 3.0 31.3 3.6 0.0 5.0 1.5 6.5 5.7 0.3 12.1 10.3 1.8 15.2 21.9 61.3 10.2 4.4 3.4 5.0 4.1 2.2 8.8 5.6 4.1 4.6 2.1 12.5 2.7 3.2 129.7 6.4 1.9 7.4 50.0 5.4 2.7 7.0 0.0 7.7 6.5 1.2 0.2 11.5 5.1 0.1 1.7 0.0 44.4 14.7 PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 199.0;Endothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.8" "Group enriched" "Detected in many" 9 "granulocytes: 5.8;monocytes: 2.4;T-cells: 2.3" "Cell line enhanced" "Detected in all" "RT4: 76.1" "Low region specificity" "Detected in all" "HPA005751, HPA071988" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Nucleoplasm "HPA005751: AB_1855350, HPA071988: AB_2686479" "unprognostic (1.98e-1)" "unprognostic (3.75e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.32e-2)" "prognostic favorable (3.62e-4)" "unprognostic (4.88e-2)" "unprognostic (3.33e-3)" "unprognostic (4.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.99e-3)" "unprognostic (2.87e-2)" "unprognostic (9.74e-2)" "unprognostic (6.71e-2)" "unprognostic (8.22e-3)" 31.2 12.2 13.0 7.2 11.2 0.7 28.0 35.9 14.8 15.3 14.0 7.5 3.2 15.9 10.3 7.1 10.1 10.7 35.2 11.4 14.9 16.2 4.0 18.5 6.2 16.7 17.3 4.1 4.7 12.1 8.5 13.3 16.8 12.0 4.9 17.9 12.5 6.1 12.0 6.4 8.6 11.5 15.5 11.2 9.9 25.4 15.9 10.8 14.2 18.5 5.3 14.8 7.4 11.4 10.9 3.6 47.4 24.4 4.6 2.0 15.2 6.3 4.6 8.2 10.1 2.1 3.2 14.3 18.9 2.5 9.9 6.4 16.9 5.8 5.3 11.1 15.0 9.3 41.8 1.6 1.5 8.3 11.8 5.8 3.3 8.7 3.2 7.8 17.3 32.8 3.5 10.0 11.8 16.7 33.4 5.1 16.9 3.1 9.6 42.0 12.7 17.0 20.4 76.1 34.4 24.9 20.5 53.5 5.7 28.5 14.9 7.3 32.4 8.7 8.0 1.5 6.2 14.1 15.8 8.5 6.9 10.9 4.5 0.0 0.2 5.8 2.0 0.3 1.9 0.3 0.4 1.8 0.0 0.0 0.1 1.1 0.0 0.0 2.4 0.3 2.3 0.6 13.0 11.2 35.9 14.8 11.4 14.9 16.7 17.3 16.8 15.5 15.9 11.4 199.0 0.0 8.4 15.7 3.1 2.5 5.4 42.1 14.8 48.3 32.0 30.1 21.1 0.0 28.8 18.4 45.9 4.4 13.9 21.7 0.0 0.6 11.8 13.9 21.0 83.3 7.8 5.9 26.2 1.2 1.1 16.2 55.5 26.2 9.5 6.1 0.0 0.0 1.7 3.3 55.9 8.6 38.7 0.0 4.4 19.9 1.2 8.4 5.4 60.9 0.9 33.5 3.1 22.1 7.1 1.4 1.5 7.9 10.1 7.2 4.5 4.2 26.7 42.8 0.0 13.3 18.0 35.9 31.7 8.0 1.8 1.4 15.7 19.2 6.6 5.0 PLA2G2C UBXN10-AS1 ENSG00000187980 "Phospholipase A2 group IIC" Q5R387 1 20161253-20186518 "Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 1.2" "Group enriched" "Detected in some" 4 "Early spermatids: 2.9;Late spermatids: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 1.6;U-698: 2.0;U-937: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.02e-3)" "unprognostic (2.75e-2)" "unprognostic (5.76e-2)" "unprognostic (3.00e-4)" "unprognostic (9.44e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (3.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.46e-1)" "unprognostic (1.22e-2)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (8.16e-2)" 0.1 0.0 0.4 0.1 0.2 0.4 0.0 0.7 0.5 0.1 0.3 1.2 0.2 0.4 0.2 0.7 0.1 0.1 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.2 0.0 0.1 0.0 0.1 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.3 0.2 0.2 0.2 0.1 0.2 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.9 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.0 0.1 1.7 0.0 0.5 0.3 0.0 0.4 0.1 0.8 0.1 0.3 0.4 0.5 0.1 0.2 0.1 0.6 0.3 0.0 0.2 0.0 0.1 0.4 0.2 0.7 0.5 0.5 0.3 0.3 0.3 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 1.3 0.1 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.6 0.0 9.8 0.3 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 318.7;brain: 394.8" "Cell type enhanced" "Detected in some" "Adipocytes: 80.5;Cardiomyocytes: 151.9;Cytotrophoblasts: 137.4;Extravillous trophoblasts: 365.5;Hofbauer cells: 71.0;Syncytiotrophoblasts: 290.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 187.8" "Group enriched" "Detected in all" 6 "dendritic cells: 187.8;T-cells: 55.0" "Cell line enhanced" "Detected in many" "A549: 135.1;ASC diff: 148.2;CAPAN-2: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" 318.7 36.2 208.5 10.2 287.0 3.1 166.8 234.7 261.6 13.3 142.8 32.8 8.7 17.6 26.6 13.2 33.0 29.1 103.0 197.7 215.3 65.0 76.5 37.6 11.6 283.0 250.7 73.4 32.4 28.6 33.4 40.3 279.8 16.4 7.6 26.6 28.9 29.9 108.9 10.7 21.8 15.8 241.2 15.9 31.9 54.7 237.1 7.1 41.2 118.7 4.4 26.7 9.6 394.8 87.7 135.1 3.7 0.2 148.2 25.1 24.1 3.2 26.9 22.3 11.2 30.8 247.1 0.0 55.3 6.9 72.4 4.4 127.4 6.8 16.9 108.0 5.0 1.3 33.3 5.4 87.8 0.0 1.3 15.2 0.7 55.4 2.2 88.1 35.4 0.0 1.6 9.6 24.0 15.3 0.2 0.6 10.8 55.0 43.0 0.0 0.0 8.7 71.2 12.3 1.7 9.7 18.0 51.5 28.7 54.6 111.6 4.5 52.2 10.0 0.7 34.0 7.7 39.6 28.0 0.3 40.1 0.0 1.0 0.1 21.1 0.1 55.0 9.1 30.3 7.4 12.1 40.5 6.4 1.2 3.9 30.0 1.3 21.0 0.6 187.8 9.3 27.2 208.5 287.0 234.7 261.6 197.7 215.3 283.0 250.7 279.8 241.2 237.1 394.8 80.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.9 0.0 0.0 0.0 0.0 137.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 365.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 290.6 2.0 0.0 0.0 0.0 PLEKHO1 "CKIP-1, OC120" ENSG00000023902 "Pleckstrin homology domain containing O1" Q53GL0 1 150149183-150164720 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 202.3" "Cell type enhanced" "Detected in many" "Early spermatids: 245.9;Langerhans cells: 159.2;Late spermatids: 390.5;Macrophages: 147.9;monocytes: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061018 Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA061018: AB_2684416" "unprognostic (1.41e-2)" "unprognostic (7.04e-3)" "unprognostic (2.01e-2)" "unprognostic (1.78e-2)" "unprognostic (3.23e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-2)" "unprognostic (8.33e-2)" "unprognostic (3.84e-2)" "unprognostic (3.18e-2)" "unprognostic (8.71e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.47e-11)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (1.87e-1)" "unprognostic (6.52e-2)" 27.7 43.2 49.9 53.9 50.1 17.9 22.6 52.8 61.6 32.3 45.5 202.3 17.8 50.7 5.2 17.5 43.5 20.6 59.3 49.5 47.9 15.9 8.7 34.9 49.5 49.8 48.1 28.1 5.1 4.1 14.9 15.1 48.0 45.5 11.5 4.2 11.0 16.2 39.6 11.2 58.4 40.4 48.9 59.9 55.8 83.2 48.0 33.9 13.0 15.2 26.0 97.5 23.6 48.9 14.3 3.4 46.3 36.0 14.4 12.7 3.8 24.8 32.9 31.8 28.1 1.0 0.4 0.4 4.7 28.5 23.9 1.2 23.3 1.1 10.3 86.7 12.1 2.8 1.9 8.9 27.1 20.0 77.7 18.5 1.0 39.8 6.2 30.6 30.6 38.5 5.4 35.9 43.9 6.7 76.0 40.0 43.7 0.0 6.4 68.1 25.2 16.2 5.6 4.1 28.8 46.9 2.0 0.2 18.7 22.1 2.4 19.4 43.4 20.8 24.1 21.9 30.1 14.0 0.4 9.2 83.4 0.2 8.2 2.6 25.9 0.5 5.6 24.8 6.0 20.0 8.2 5.9 20.1 17.2 5.6 4.7 30.9 4.1 23.4 27.3 6.7 9.2 49.9 50.1 52.8 61.6 49.5 47.9 49.8 48.1 48.0 48.9 48.0 48.9 23.5 35.3 8.9 32.3 65.1 21.5 92.7 2.9 4.6 7.9 11.8 17.9 36.4 2.8 2.9 0.0 0.0 1.7 97.5 0.5 1.9 8.8 245.9 17.9 50.2 58.9 17.8 4.2 13.5 7.8 3.3 29.4 4.6 22.0 5.7 24.5 42.5 1.8 107.1 8.4 24.3 0.9 10.2 85.5 159.2 390.5 17.4 147.9 24.9 21.5 151.1 34.0 23.7 9.0 1.6 10.7 0.0 24.5 23.7 50.1 0.2 0.5 1.3 6.2 72.3 7.5 105.0 122.5 17.5 2.9 14.2 1.5 45.6 8.6 0.4 23.0 PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1508.4;Oligodendrocytes: 470.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Cell line enhanced" "Detected in some" "HHSteC: 19.4;U-2197: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" 12.4 9.4 13.3 7.3 14.1 5.2 11.5 9.6 13.3 12.7 16.8 5.3 4.2 10.7 3.5 7.5 10.1 17.4 10.2 11.3 25.6 10.7 3.1 17.1 2.4 18.0 17.3 9.4 3.6 16.2 3.3 4.7 19.2 7.6 4.6 18.2 6.2 7.7 5.0 15.5 7.1 16.2 16.2 9.4 3.8 5.9 22.3 2.5 6.8 10.0 2.8 8.5 8.9 29.1 0.0 0.0 5.8 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 7.7 2.2 1.8 0.0 0.0 0.7 2.8 8.6 0.4 19.4 0.0 0.0 7.7 0.6 0.0 2.3 8.9 0.0 0.0 0.1 1.7 0.9 1.1 0.6 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 0.2 2.4 0.4 0.0 1.8 0.8 0.9 0.0 7.6 3.9 45.9 0.0 0.1 0.0 0.0 3.5 0.1 0.0 10.7 57.5 11.8 1.3 33.4 2.7 0.0 0.0 0.3 36.0 0.0 0.0 0.0 81.6 4.4 37.3 1.6 0.0 17.7 13.3 14.1 9.6 13.3 11.3 25.6 18.0 17.3 19.2 16.2 22.3 29.1 101.4 16.0 8.9 131.9 2.6 36.8 23.8 12.3 41.5 44.2 14.4 45.3 10.9 15.7 10.9 5.5 8.4 0.9 2.9 7.1 0.0 6.9 2.9 16.5 7.6 45.3 3.0 10.5 190.9 0.0 8.1 97.2 1.1 19.4 31.6 80.9 82.1 4.2 94.3 1.7 59.9 27.3 8.2 91.3 46.3 2.1 19.3 147.7 7.2 1508.4 94.5 25.5 5.2 158.3 470.2 1.0 16.6 57.2 3.8 5.5 16.0 22.2 3.0 73.6 19.7 110.1 12.7 1.6 1.2 35.5 38.1 1.2 4.2 71.4 8.8 11.7 PLXND1 KIAA0620 ENSG00000004399 "Plexin D1" Q9Y4D7 3 129555214-129606676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Endothelial cells: 102.1;Hepatic stellate cells: 132.1;Hofbauer cells: 81.5;Kupffer cells: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 10.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 392.3;HSkMC: 286.1;HUVEC TERT2: 346.1;TIME: 414.4" "Group enriched" "Detected in all" 4 "amygdala: 36.6;basal ganglia: 33.1;cerebral cortex: 27.4;hippocampal formation: 26.3" "Low region specificity" "Detected in all" CAB020819 Approved NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB020819: " "unprognostic (8.97e-3)" "unprognostic (1.95e-1)" "unprognostic (6.30e-2)" "unprognostic (8.35e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-3)" "unprognostic (6.35e-2)" "unprognostic (4.51e-2)" "unprognostic (3.69e-1)" "unprognostic (3.02e-3)" "unprognostic (3.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.93e-7)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (3.17e-2)" "unprognostic (1.00e-2)" 72.6 22.1 32.0 37.4 38.1 26.5 47.4 36.2 35.6 58.4 26.1 19.5 6.0 33.5 17.6 21.5 35.0 39.4 39.8 29.3 34.2 24.7 18.3 67.5 34.7 48.7 43.5 16.3 13.9 18.0 11.1 112.4 43.8 19.0 16.9 3.5 13.3 27.0 12.9 19.5 20.9 52.6 38.8 33.6 15.8 10.8 49.0 62.7 29.5 39.8 23.2 37.1 26.8 43.2 10.0 57.7 47.4 16.3 392.3 167.9 98.4 42.8 123.1 25.5 29.5 13.4 8.1 2.1 179.9 152.9 13.2 0.6 25.9 0.6 7.5 1.9 3.2 40.7 30.2 61.4 44.8 13.5 11.0 286.1 1.7 26.4 2.8 36.6 346.1 2.1 14.5 1.5 34.8 31.0 2.4 44.2 11.8 2.4 8.0 47.4 32.0 51.8 10.2 2.3 27.6 1.1 11.0 3.5 15.9 107.6 15.5 59.7 414.4 21.5 28.5 0.6 32.4 1.9 2.2 19.9 7.5 29.2 19.0 0.0 10.7 0.0 1.7 5.1 6.8 0.0 1.2 1.4 2.9 0.0 0.0 0.1 0.2 3.1 5.2 3.6 0.0 1.7 32.0 38.1 36.2 35.6 29.3 34.2 48.7 43.5 43.8 38.8 49.0 43.2 107.3 3.2 27.2 12.4 3.6 8.0 0.4 2.1 0.6 0.1 7.6 3.4 10.6 5.7 3.1 0.0 0.0 7.1 16.9 0.2 0.0 1.4 1.4 3.7 52.5 102.1 13.1 12.6 10.4 3.5 16.4 19.5 5.6 6.2 22.2 1.3 132.1 7.7 81.5 0.0 0.6 3.2 6.1 75.6 31.8 1.8 38.8 41.7 8.8 27.2 29.4 6.5 10.3 0.5 27.7 2.7 0.1 13.9 12.9 0.5 0.0 0.3 1.2 0.3 32.9 14.4 37.1 0.6 4.0 1.5 4.4 5.3 14.4 49.5 0.5 0.6 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 PMP22 "CMT1A, GAS3, HMSNIA, HNPP, Sp110" ENSG00000109099 "Peripheral myelin protein 22" Q01453 17 15229773-15272292 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes, Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 404.1;Hofbauer cells: 558.3;Leydig cells: 324.3;Melanocytes: 343.3;Proximal enterocytes: 580.6;Skeletal myocytes: 288.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 32.2;eosinophil: 43.0;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 22 "dendritic cells: 23.8;granulocytes: 43.0" "Cell line enhanced" "Detected in many" "ASC diff: 383.5;HMC-1: 263.7;SuSa: 333.9;WM-115: 448.8" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (3.00e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-1)" "unprognostic (4.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.28e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-1)" "unprognostic (4.33e-2)" "unprognostic (7.70e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.83e-2)" "unprognostic (5.45e-2)" "unprognostic (2.88e-1)" "unprognostic (1.08e-2)" 275.6 45.4 113.6 55.1 161.0 4.9 184.5 153.2 140.7 192.2 77.9 212.2 41.7 142.1 36.5 68.2 163.4 106.5 167.6 113.5 129.0 53.5 11.7 208.4 27.8 163.3 144.2 102.9 22.8 10.8 26.3 201.9 159.9 81.2 74.7 6.5 77.5 80.6 252.4 112.7 239.1 122.0 135.0 27.9 96.2 20.7 141.1 17.3 95.3 127.0 21.8 208.9 157.4 216.7 7.0 44.1 61.9 62.2 383.5 167.1 12.6 60.5 68.8 58.7 38.0 48.7 1.1 0.1 7.0 172.3 22.7 0.7 74.0 1.1 15.4 0.2 13.9 4.3 76.7 17.2 201.8 0.1 263.7 126.9 1.1 32.6 1.8 72.1 66.1 2.8 24.5 0.8 33.2 6.1 0.2 2.0 3.5 4.0 74.7 22.0 39.3 0.0 44.6 4.8 0.1 40.6 16.6 0.6 134.2 333.9 0.2 0.5 81.4 12.7 45.7 216.9 62.0 0.5 0.1 0.3 84.7 0.1 448.8 32.2 1.4 43.0 0.0 0.9 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.2 0.1 0.2 23.8 0.0 0.9 113.6 161.0 153.2 140.7 113.5 129.0 163.3 144.2 159.9 135.0 141.1 216.7 86.6 28.9 11.5 50.9 2.8 90.1 6.7 6.1 9.6 1.4 43.0 82.7 68.4 4.3 7.4 0.0 0.0 8.8 2.5 9.1 3.9 4.5 17.7 20.1 118.6 148.0 4.8 10.1 3.7 3.3 23.1 404.1 2.6 11.0 119.7 25.0 88.5 0.9 558.3 0.0 1.8 23.8 0.0 23.4 116.8 11.0 324.3 93.0 343.3 29.0 11.8 61.6 0.0 46.8 217.1 1.7 25.2 246.4 1.9 4.9 580.6 0.7 3.0 2.2 230.1 288.8 141.1 3.0 4.8 3.0 103.0 19.0 8.7 49.2 17.9 5.2 PNMA1 MA1 ENSG00000176903 "PNMA family member 1" Q8ND90 14 73711783-73714384 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 84.2;Peritubular cells: 84.7;Spermatocytes: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003817, HPA015007" Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Focal adhesion sites" "HPA003817: AB_1079646, HPA015007: AB_1855502" "unprognostic (2.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (7.49e-5)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.90e-1)" "unprognostic (5.35e-2)" "unprognostic (3.63e-1)" "unprognostic (5.58e-2)" "unprognostic (4.58e-2)" "unprognostic (1.67e-3)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (2.23e-3)" "prognostic unfavorable (4.51e-5)" 35.5 30.2 75.0 20.3 80.5 8.8 20.6 55.5 85.6 37.6 34.7 56.7 13.9 46.3 54.6 23.4 38.1 24.6 23.3 77.3 90.0 27.8 4.9 15.5 16.4 62.1 62.5 53.4 9.2 8.0 53.1 21.4 62.9 48.8 16.5 59.9 10.9 89.3 12.0 9.8 24.9 52.3 66.9 19.2 26.0 71.0 78.4 19.0 18.5 10.4 12.5 41.7 26.6 70.3 48.2 42.8 72.3 54.1 53.1 56.0 29.9 49.8 27.8 44.5 32.5 40.6 29.2 1.1 33.8 60.7 42.4 31.6 56.0 29.4 45.7 45.7 34.7 27.2 35.8 30.7 56.8 15.3 41.6 49.8 35.1 53.4 33.5 87.4 68.1 28.7 23.9 29.3 61.2 117.6 30.5 37.1 21.8 24.6 149.0 47.5 45.0 1.1 58.8 1.5 85.4 65.5 87.5 19.9 40.4 43.6 97.0 25.6 66.5 89.3 71.7 54.9 41.1 25.7 42.9 14.2 88.3 21.4 30.3 2.9 1.8 4.7 8.5 3.5 5.8 2.8 10.9 8.7 3.9 3.1 10.4 10.0 1.6 5.6 5.3 0.6 14.2 7.3 75.0 80.5 55.5 85.6 77.3 90.0 62.1 62.5 62.9 66.9 78.4 70.3 13.1 6.4 3.0 21.9 8.8 3.8 6.8 5.0 6.2 48.6 7.0 7.5 19.9 2.8 4.1 14.7 12.5 7.5 10.4 6.7 15.6 10.1 84.2 32.2 30.6 13.5 18.7 3.0 31.4 6.7 11.3 20.5 14.3 10.2 16.5 16.6 20.0 1.6 15.6 58.9 28.9 5.4 14.2 6.8 25.9 57.6 32.6 18.8 19.6 12.2 14.1 65.2 10.3 17.1 21.7 30.2 1.4 84.7 10.9 7.4 1.6 26.6 23.1 49.1 72.3 31.2 44.1 87.2 44.4 4.7 3.8 6.0 20.0 43.8 2.5 3.7 PPP1R14A "CPI-17, PPP1INL" ENSG00000167641 "Protein phosphatase 1 regulatory inhibitor subunit 14A" Q96A00 19 38251237-38256532 "Plasma proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 492.0;intestine: 450.3" "Cell type enhanced" "Detected in many" "Adipocytes: 332.5;Granulosa cells: 435.0;Leydig cells: 341.1;Peritubular cells: 656.0;Sertoli cells: 979.5;Smooth muscle cells: 465.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 299.4;naive B-cell: 283.9;plasmacytoid DC: 246.9" "Group enriched" "Detected in many" 24 "B-cells: 299.4;dendritic cells: 246.9" "Group enriched" "Detected in some" 4 "A549: 164.1;EFO-21: 112.2;K-562: 64.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005044, CAB009803, HPA042097, HPA054534" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA 880000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Nuclear bodies" "CAB005044: AB_562091, CAB009803: AB_2168720, HPA042097: AB_2677846, HPA054534: AB_2682518" "unprognostic (5.40e-2)" "unprognostic (4.00e-3)" "unprognostic (4.02e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-1)" "unprognostic (8.92e-3)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (1.96e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.25e-5)" "prognostic unfavorable (7.12e-4)" "unprognostic (4.13e-1)" "unprognostic (5.81e-2)" "unprognostic (2.22e-2)" 134.0 144.2 175.2 22.1 347.5 2.9 111.9 321.5 226.5 149.7 63.2 450.3 18.6 273.5 5.2 47.6 153.7 14.8 94.6 175.2 219.6 53.3 17.9 163.1 2.6 402.3 322.9 125.1 31.1 2.8 12.6 34.1 336.3 142.0 12.6 0.3 19.0 86.1 27.5 28.6 82.1 57.2 222.0 101.2 140.3 77.6 365.3 1.7 25.8 12.3 1.4 301.6 106.1 492.0 0.0 164.1 0.4 0.0 1.0 0.0 6.1 10.8 0.0 0.1 0.0 12.8 0.2 0.0 112.2 1.0 0.0 0.5 13.6 0.2 0.0 1.4 0.0 25.5 0.0 0.0 4.6 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 64.5 0.3 0.0 0.8 0.0 0.3 4.9 0.0 0.0 0.2 2.4 0.4 0.4 0.0 3.5 0.2 0.0 0.0 0.1 9.2 0.0 0.4 0.4 0.0 0.8 0.4 0.0 0.4 0.0 0.5 0.2 0.0 0.1 11.3 0.6 1.2 0.1 0.7 0.2 299.4 0.2 0.4 44.3 283.9 0.6 0.1 1.7 8.7 0.2 246.9 0.2 21.6 175.2 347.5 321.5 226.5 175.2 219.6 402.3 322.9 336.3 222.0 365.3 492.0 332.5 0.0 1.1 1.3 29.9 9.6 3.0 1.2 3.4 0.4 8.8 209.8 19.6 2.8 0.7 0.0 0.0 48.3 48.7 32.7 0.0 0.7 14.1 15.4 239.5 108.5 1.8 34.7 0.5 10.9 7.4 66.8 2.0 10.8 3.8 435.0 224.5 2.3 9.5 0.0 0.6 0.4 0.0 5.6 24.6 42.1 341.1 41.4 8.8 14.0 66.1 0.5 4.1 3.5 155.6 2.2 2.6 656.0 4.8 2.4 3.8 0.3 0.0 1.6 979.5 8.7 465.2 9.9 46.2 0.6 8.0 26.4 3.7 66.0 0.4 1.2 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRICKLE2 DKFZp686D143 ENSG00000163637 "Prickle planar cell polarity protein 2" Q7Z3G6 3 64092236-64445476 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 114.3;Excitatory neurons: 185.5;Inhibitory neurons: 232.4;Microglial cells: 112.4;Oligodendrocyte precursor cells: 103.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.1;ASC TERT1: 14.9;HSkMC: 22.1;U-87 MG: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035493 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA035493: AB_10696504" "unprognostic (2.87e-1)" "unprognostic (4.31e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-1)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (1.92e-1)" "unprognostic (3.83e-2)" "unprognostic (3.03e-2)" "unprognostic (6.35e-2)" "unprognostic (1.32e-3)" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (9.04e-3)" "unprognostic (1.77e-1)" 20.8 3.0 14.1 3.9 14.9 0.3 8.0 3.4 15.8 16.4 9.1 18.4 2.3 17.3 6.8 7.7 11.7 8.8 5.6 28.5 10.0 3.8 3.1 10.6 0.8 4.4 8.9 8.4 3.8 5.4 5.6 5.6 6.2 7.3 4.6 10.1 4.9 13.8 1.9 4.3 5.9 16.6 6.3 1.4 8.1 1.7 11.7 1.0 6.9 3.9 1.0 12.4 8.8 9.3 0.0 4.7 1.3 0.1 24.1 14.9 0.0 3.5 4.5 2.8 4.2 8.3 0.1 0.0 0.5 3.4 7.6 0.1 0.0 3.2 2.8 3.3 0.1 0.0 0.5 0.1 6.7 0.0 0.0 22.1 4.0 8.2 3.5 8.4 1.7 0.0 0.0 1.8 3.9 4.6 0.0 0.1 3.0 0.0 0.1 0.0 0.2 0.1 4.5 11.7 1.2 0.2 0.0 0.9 0.1 7.7 1.6 0.1 0.1 11.9 5.4 2.9 6.9 3.7 0.0 0.7 15.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.1 14.9 3.4 15.8 28.5 10.0 4.4 8.9 6.2 6.3 11.7 9.3 12.4 0.0 10.9 114.3 1.5 6.2 4.1 7.3 7.4 25.6 4.3 8.4 6.2 1.5 7.3 3.7 64.6 1.4 0.3 1.6 0.0 2.7 15.1 24.7 47.5 9.5 0.0 0.0 185.5 0.4 0.4 20.3 0.0 8.7 0.0 5.2 33.5 1.7 4.1 16.8 232.4 0.6 4.1 1.2 1.8 3.5 9.9 0.6 5.4 112.4 0.0 7.5 1.0 103.5 26.4 0.7 0.3 23.0 0.2 0.9 0.0 6.2 7.6 4.4 13.1 14.6 14.3 2.0 1.0 6.2 3.0 4.9 0.6 6.6 1.1 2.7 PRIMA1 PRIMA ENSG00000175785 "Proline rich membrane anchor 1" Q86XR5 14 93718298-93788485 "Predicted membrane proteins" "Neurotransmitter degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.7" "Group enriched" "Detected in some" 9 "Muller glia cells: 35.5;Oligodendrocytes: 54.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HAP1: 5.2;Hep G2: 3.3;NTERA-2: 2.3;SCLC-21H: 8.3;SH-SY5Y: 8.2" "Region enhanced" "Detected in many" "basal ganglia: 18.1" "Low region specificity" "Detected in all" "HPA046671, HPA060047" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "Nucleoli, Cytosol" "HPA046671: AB_2679744, HPA060047: AB_2684194" "unprognostic (3.60e-2)" "unprognostic (1.97e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.03e-2)" "unprognostic (3.73e-2)" "unprognostic (1.07e-1)" "unprognostic (5.81e-2)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (8.94e-2)" "unprognostic (6.61e-3)" "prognostic unfavorable (2.62e-7)" "unprognostic (2.33e-2)" "unprognostic (2.67e-1)" "unprognostic (7.94e-4)" "unprognostic (4.57e-3)" 5.8 3.0 6.1 2.9 11.3 0.0 3.8 10.8 12.3 17.5 2.5 53.7 2.1 13.9 2.1 8.0 18.3 1.6 8.8 5.2 7.9 2.5 0.8 1.0 0.1 17.1 11.3 5.4 1.3 0.0 0.7 1.0 14.7 15.6 3.7 5.7 5.0 5.0 0.9 3.4 21.6 8.1 12.7 0.2 20.0 1.7 9.1 0.2 1.7 1.4 2.3 11.0 14.4 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 5.2 0.0 0.0 0.1 0.3 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.3 8.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 11.3 10.8 12.3 5.2 7.9 17.1 11.3 14.7 12.7 9.1 18.4 0.2 0.0 0.0 1.3 0.0 0.5 1.0 0.3 0.6 2.6 0.4 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.4 0.2 0.0 0.0 0.2 0.0 0.0 3.4 2.6 0.6 0.0 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.0 1.2 2.8 0.1 0.0 0.0 0.0 35.5 0.0 2.0 54.7 0.1 0.0 0.0 1.2 0.7 0.0 0.1 0.0 0.3 0.0 4.9 0.3 0.7 1.4 0.6 0.3 0.0 0.0 0.0 0.0 0.1 PRTFDC1 HHGP ENSG00000099256 "Phosphoribosyl transferase domain containing 1" Q9NRG1 10 24848614-24952606 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 136.1;Oligodendrocyte precursor cells: 111.6;Oligodendrocytes: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 4.4" "Lineage enriched" "Detected in single" 8 "NK-cells: 4.4" "Cell line enhanced" "Detected in many" "CACO-2: 75.9;CAPAN-2: 94.3;HEL: 56.2" "Low region specificity" "Detected in all" HPA021458 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Golgi apparatus, Cytosol" "HPA021458: AB_1855793" "unprognostic (2.61e-1)" "unprognostic (3.47e-1)" "unprognostic (3.69e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (9.49e-3)" "unprognostic (2.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (3.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (7.66e-3)" "unprognostic (1.94e-2)" 5.4 22.2 21.7 4.5 28.7 0.9 7.6 24.9 27.2 12.9 16.1 9.9 17.7 15.8 7.4 5.5 9.8 14.8 10.9 22.4 24.6 4.8 2.8 4.3 4.2 26.7 24.0 20.2 4.6 13.4 11.4 2.9 28.0 7.8 11.3 16.5 9.7 8.2 1.3 1.8 17.1 9.8 25.8 3.2 17.5 2.2 23.7 6.8 5.3 2.8 3.2 7.4 6.3 37.1 19.5 41.3 30.2 12.4 4.9 24.4 0.0 20.2 15.1 14.2 19.3 75.9 94.3 0.0 3.1 23.7 1.2 10.7 34.7 0.0 22.0 0.0 1.4 56.2 7.6 0.1 14.6 0.0 0.0 7.1 0.2 7.7 0.0 13.3 22.6 2.2 18.6 10.5 6.8 0.5 8.8 0.1 20.9 3.3 0.7 9.7 0.1 0.2 12.7 0.5 21.5 0.9 19.3 0.1 0.0 0.6 1.1 4.3 12.2 6.3 15.5 23.1 12.2 0.9 0.0 0.0 16.8 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 4.4 0.0 0.1 0.0 0.9 21.7 28.7 24.9 27.2 22.4 24.6 26.7 24.0 28.0 25.8 23.7 37.1 3.5 0.0 0.5 136.1 0.7 2.7 4.6 5.4 2.8 10.2 1.1 5.8 8.6 7.2 3.9 3.7 2.1 1.0 0.8 3.8 5.9 5.8 1.4 1.5 27.3 2.8 5.4 3.0 38.2 0.5 4.9 20.6 12.2 2.2 0.0 25.1 7.5 0.1 7.2 6.7 43.0 7.3 0.0 0.9 3.1 1.0 12.2 7.8 3.6 24.4 1.5 45.8 0.0 111.6 148.2 2.3 2.1 9.8 1.3 1.1 12.2 0.1 1.1 15.9 0.0 16.4 10.4 3.4 6.3 0.4 2.8 0.8 1.0 22.7 11.6 1.5 PRUNE2 "A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367" ENSG00000106772 "Prune homolog 2 with BCH domain" Q8WUY3 9 76611376-76906114 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.6;intestine: 110.9" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 918.7" "Cancer enhanced" "Detected in many" "renal cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 51.1;LHCN-M2: 83.2;RH-30: 71.5;RPTEC TERT1: 40.1" "Low region specificity" "Detected in all" "HPA022470, HPA031079" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Nucleoplasm, Nucleoli" "HPA022470: AB_1845832, HPA031079: AB_10603230" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (6.06e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (2.43e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-2)" "unprognostic (3.60e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-2)" "unprognostic (9.79e-2)" "prognostic favorable (1.37e-6)" "unprognostic (7.75e-2)" "unprognostic (1.06e-1)" "unprognostic (3.25e-3)" "unprognostic (3.80e-4)" 11.3 23.2 26.9 11.9 82.9 2.9 5.2 49.5 54.7 16.6 0.0 110.9 7.1 50.6 18.5 34.0 29.4 16.4 8.9 26.9 48.4 15.4 1.9 5.1 2.8 90.0 52.8 4.7 4.3 4.0 30.9 4.0 76.4 47.6 18.5 39.0 14.6 64.8 16.7 5.4 27.7 55.3 31.7 4.4 37.1 4.9 53.1 0.9 2.6 56.8 2.5 69.2 14.4 120.6 0.0 0.0 1.5 0.0 51.1 25.8 0.2 1.8 3.6 6.6 14.7 0.4 0.0 0.3 3.9 4.5 13.6 0.0 0.1 0.0 18.0 0.4 2.9 6.3 3.7 0.0 8.5 0.1 0.3 28.7 0.1 26.7 0.7 15.1 14.4 0.4 0.0 20.8 83.2 0.1 4.6 1.8 4.0 0.0 0.0 0.5 71.5 0.3 40.1 0.0 17.4 0.0 0.0 0.3 4.9 2.8 0.1 0.7 11.9 14.2 0.7 34.9 1.2 22.2 3.2 0.0 11.5 0.3 0.0 0.3 0.5 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.4 0.3 0.2 0.1 0.0 0.2 26.9 82.9 49.5 54.7 26.9 48.4 90.0 52.8 76.4 31.7 53.1 120.6 0.4 0.0 1.1 27.7 0.0 2.3 0.4 0.5 0.0 47.5 1.2 3.4 11.1 0.0 1.0 11.0 0.0 0.0 1.6 3.5 1.9 0.0 12.6 37.7 4.7 3.7 54.3 0.0 152.4 0.5 0.2 2.9 3.1 34.7 0.0 0.1 21.8 0.2 3.2 15.2 65.4 36.4 4.1 3.1 3.1 30.0 0.9 2.3 5.4 13.1 1.7 9.9 2.1 134.7 918.7 0.4 8.8 1.5 0.1 5.1 9.9 20.3 17.0 6.5 0.0 27.2 9.6 4.3 4.2 0.0 1.4 0.0 0.7 0.5 5.2 0.6 PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.7" "Cell type enhanced" "Detected in many" "Late spermatids: 237.5;Leydig cells: 191.0;Peritubular cells: 444.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 6.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "NTERA-2: 29.6;WM-115: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "CAB013717: , HPA075072: AB_2686733" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (3.16e-1)" "unprognostic (1.79e-2)" "unprognostic (3.22e-2)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" "unprognostic (3.54e-3)" "unprognostic (2.63e-1)" "unprognostic (8.66e-3)" "unprognostic (1.52e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-6)" "unprognostic (8.63e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-1)" "unprognostic (2.82e-1)" 3.0 3.5 9.5 4.0 11.6 0.7 2.8 24.6 5.6 26.7 2.7 11.3 8.1 15.6 2.7 2.9 7.1 8.1 2.9 4.7 17.8 4.6 2.2 5.5 2.2 16.0 12.7 5.0 6.4 2.5 2.1 3.8 8.0 6.8 12.3 8.3 7.5 4.0 3.0 3.2 11.6 2.4 7.0 3.3 12.5 14.5 24.0 2.1 4.7 4.8 3.0 7.2 2.9 4.5 10.1 4.7 20.3 12.9 3.0 5.0 11.4 1.9 1.7 2.2 1.4 4.9 4.8 8.0 3.3 3.8 4.4 22.3 11.7 1.6 1.4 7.9 7.8 0.0 4.8 2.3 2.7 0.2 4.2 4.7 2.4 2.2 1.4 4.3 4.2 3.5 7.3 9.1 1.0 1.9 0.1 3.2 29.6 7.2 1.8 0.0 15.5 4.2 1.6 1.5 13.8 7.0 7.1 6.8 2.9 18.8 1.8 2.1 1.1 2.6 12.9 13.6 1.5 18.0 16.8 5.3 3.8 3.9 71.0 0.0 0.0 0.0 6.1 0.0 3.3 0.7 1.1 2.5 0.0 0.2 1.9 2.2 0.0 0.3 0.0 0.0 1.2 1.7 9.5 11.6 24.6 5.6 4.7 17.8 16.0 12.7 8.0 7.0 24.0 4.5 6.0 0.0 6.4 49.0 3.0 4.0 2.7 3.0 4.6 20.3 3.5 4.6 5.9 25.8 2.7 0.0 41.7 3.0 11.8 2.0 5.9 3.5 88.4 12.2 89.8 5.4 21.7 0.4 15.2 4.2 1.9 27.2 1.1 11.0 1.3 2.6 6.4 2.9 0.8 20.2 10.7 11.0 4.1 0.9 1.2 237.5 191.0 1.4 12.4 4.7 0.8 55.6 54.6 39.7 20.5 2.4 3.1 444.5 3.1 4.9 3.1 1.6 5.5 13.4 39.5 4.8 9.4 4.4 35.5 3.0 4.4 1.4 6.5 71.7 4.7 1.4 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PTPRU "FMI, hPTP-J, PCP-2, PTP, PTPRO" ENSG00000060656 "Protein tyrosine phosphatase receptor type U" Q92729 1 29236516-29326813 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 22.1;Respiratory ciliated cells: 24.3;Rod photoreceptor cells: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 95.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB011476, HPA039832" Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB011476: AB_442989, HPA039832: AB_10793923" "unprognostic (7.81e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-3)" "unprognostic (6.13e-2)" "prognostic unfavorable (7.92e-4)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.17e-1)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (4.55e-3)" "unprognostic (3.39e-3)" "unprognostic (6.83e-2)" "unprognostic (1.19e-2)" "unprognostic (6.82e-2)" "unprognostic (4.92e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-1)" 7.1 2.1 12.6 1.1 18.3 0.1 6.9 6.4 16.1 31.1 6.1 5.3 0.7 11.9 3.3 4.3 11.5 4.8 8.7 14.4 10.0 4.9 9.1 9.9 0.6 29.1 18.9 13.0 11.1 9.2 10.2 11.5 28.0 14.0 1.4 18.8 14.6 12.9 17.5 10.1 2.4 1.9 6.3 2.1 5.9 4.0 9.7 1.0 5.2 9.9 1.3 12.3 12.2 11.1 8.1 10.8 0.6 1.6 28.7 1.0 95.7 8.4 7.4 0.3 0.5 9.4 34.7 1.4 16.2 1.6 1.0 42.3 38.5 27.1 0.1 0.5 19.7 1.7 12.1 39.8 12.1 0.0 1.7 13.3 14.4 0.0 2.5 11.3 0.2 4.7 0.3 1.3 7.6 13.2 0.5 0.2 15.8 15.9 4.9 0.0 11.3 0.5 11.7 39.4 32.3 42.0 8.5 26.3 5.8 6.6 15.6 1.8 7.1 1.4 9.3 2.6 1.2 0.8 1.1 0.1 18.8 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 6.4 16.1 14.4 10.0 29.1 18.9 28.0 6.3 9.7 11.1 1.0 9.6 13.6 0.7 0.1 1.5 6.7 22.1 1.8 5.3 4.8 5.6 5.2 5.7 20.2 5.5 12.5 18.7 0.5 0.3 0.0 6.2 1.3 8.6 9.4 1.3 0.0 0.0 12.1 2.7 10.5 4.6 0.0 10.1 1.3 0.7 1.8 5.3 2.6 0.0 8.0 0.2 6.1 0.6 1.1 1.2 4.7 0.4 8.8 3.7 0.0 16.7 0.0 8.5 4.4 7.3 0.0 7.2 1.2 6.5 0.0 0.3 24.3 42.6 6.6 5.5 4.1 2.1 6.4 0.2 0.6 9.0 0.6 0.0 0.2 10.0 PTTG1IP "C21orf1, C21orf3, PBF" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB034146: AB_1568894, HPA061827: AB_2684620" "unprognostic (1.78e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (5.24e-3)" "unprognostic (3.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (9.30e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.40e-4)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.90e-1)" 127.8 131.8 147.6 98.4 158.9 92.0 114.0 150.8 146.8 131.1 131.1 132.7 123.2 132.4 118.5 89.1 109.4 141.8 164.3 138.1 168.7 157.6 130.5 160.5 75.3 178.8 152.9 110.7 85.6 84.1 68.8 180.1 169.9 108.5 111.5 29.7 118.3 151.4 70.7 88.9 127.3 145.0 152.0 97.7 169.9 66.9 175.3 57.9 127.4 63.2 62.0 139.6 93.3 157.5 245.3 134.6 155.3 148.2 300.6 174.8 127.0 212.9 309.8 174.1 166.6 290.0 323.9 32.9 789.8 344.4 417.0 109.8 73.0 140.2 161.1 56.3 81.0 254.3 80.0 260.1 293.8 97.6 83.5 269.9 225.1 189.1 130.8 346.3 376.6 88.6 131.7 83.1 539.5 106.0 71.0 99.5 166.8 352.9 169.8 70.4 158.4 162.0 735.6 82.7 117.2 182.0 240.0 262.5 482.0 188.7 203.7 163.7 511.8 216.9 126.5 170.6 340.0 78.5 79.4 42.2 146.7 220.6 199.8 336.2 181.2 109.1 48.4 146.7 79.5 25.5 62.7 51.3 203.3 23.6 59.7 41.0 248.8 67.3 167.0 92.5 87.3 223.7 147.6 158.9 150.8 146.8 138.1 168.7 178.8 152.9 169.9 152.0 175.3 157.5 140.9 394.2 169.6 39.8 28.0 50.7 84.1 181.3 61.5 14.6 102.0 96.8 173.0 75.8 248.9 145.3 6.2 218.6 56.8 321.4 49.0 323.0 51.5 115.0 115.0 191.6 79.3 37.8 8.5 120.6 72.7 117.1 140.6 187.7 81.5 181.3 124.2 102.2 109.3 11.8 10.7 89.1 130.2 88.0 69.6 98.7 72.1 136.3 87.2 22.5 91.1 78.8 51.5 20.1 31.9 294.3 255.2 98.9 36.4 112.8 268.1 71.2 192.3 15.2 65.7 61.1 127.9 73.7 43.4 92.4 42.9 366.7 45.6 54.6 100.3 169.9 RAB31 Rab22B ENSG00000168461 "RAB31, member RAS oncogene family" Q13636 18 9708275-9862551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 180.9;Kupffer cells: 283.8;Langerhans cells: 208.9;Macrophages: 221.6;monocytes: 193.2;Oligodendrocyte precursor cells: 184.0;Syncytiotrophoblasts: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 137.9" "Group enriched" "Detected in many" 8 "dendritic cells: 44.9;granulocytes: 137.9;monocytes: 51.6" "Cell line enhanced" "Detected in many" "GAMG: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019717 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "HPA019717: AB_10601493" "unprognostic (4.61e-2)" "unprognostic (1.65e-2)" "unprognostic (8.53e-2)" "unprognostic (1.13e-1)" "unprognostic (1.23e-2)" "unprognostic (5.70e-2)" "unprognostic (3.07e-2)" "unprognostic (5.99e-2)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.75e-1)" "unprognostic (6.26e-2)" "unprognostic (3.98e-3)" "unprognostic (8.71e-3)" "unprognostic (1.61e-1)" "unprognostic (6.34e-2)" 35.0 104.8 83.1 42.2 90.5 59.7 22.2 89.1 92.6 85.2 67.7 45.8 11.1 56.2 9.4 31.8 28.8 45.6 20.9 75.9 93.1 16.3 10.5 58.9 22.4 96.6 95.1 44.2 7.0 8.6 10.0 56.5 96.8 21.3 17.7 12.6 13.7 48.7 5.4 12.9 23.7 85.8 91.5 31.3 31.7 42.6 99.3 9.8 25.9 10.5 22.6 54.5 35.2 92.1 2.7 14.4 105.0 0.2 136.7 70.5 74.6 25.4 71.0 18.2 15.8 4.1 14.4 0.1 16.6 99.7 175.3 9.9 25.9 32.6 21.1 6.5 14.6 89.3 104.4 1.8 158.0 7.4 94.2 76.5 6.6 42.1 32.5 78.0 47.4 0.0 22.2 0.4 42.6 11.9 0.1 11.5 22.2 1.2 6.3 0.1 11.5 3.7 13.9 0.3 2.0 6.8 96.4 60.7 34.7 87.5 6.9 48.4 51.9 112.9 56.4 78.3 37.5 19.4 5.7 0.1 153.7 0.1 47.1 137.9 51.6 21.3 0.1 47.2 0.1 9.8 0.2 0.1 44.9 6.7 0.1 0.1 74.4 4.3 50.2 5.2 0.2 19.5 83.1 90.5 89.1 92.6 75.9 93.1 96.6 95.1 96.8 91.5 99.3 92.1 10.0 176.3 33.3 91.4 32.4 15.8 17.7 30.8 23.3 3.2 13.2 12.6 10.6 12.8 51.2 11.0 0.0 180.9 11.0 8.7 7.9 7.9 5.4 10.2 86.0 33.1 0.0 2.5 8.1 19.6 19.0 55.5 5.6 6.2 7.6 72.9 30.0 1.9 157.0 151.4 19.6 0.6 8.2 283.8 208.9 10.9 17.7 221.6 7.2 75.9 193.2 21.5 4.1 184.0 7.0 19.4 1.4 117.4 12.0 27.3 0.0 4.0 47.0 3.9 39.5 14.0 87.3 1.7 4.2 14.5 16.1 186.6 5.1 36.3 0.3 38.8 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.6;Astrocytes: 143.0;Collecting duct cells: 69.9;Endothelial cells: 53.0;Oligodendrocytes: 45.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 26.9;HUVEC TERT2: 12.1;NB-4: 14.3;RPTEC TERT1: 13.3;TIME: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 44.6 2.8 29.2 2.6 35.0 1.4 44.0 30.3 29.2 26.0 12.5 9.9 4.0 16.4 6.9 13.2 24.1 13.2 21.1 31.4 21.3 40.0 1.9 11.9 4.4 33.6 29.6 38.2 4.7 5.8 6.4 8.9 28.0 13.5 2.4 0.9 21.2 11.0 11.4 9.8 8.8 5.1 22.4 16.2 11.5 3.5 28.9 1.6 32.4 9.0 2.1 14.9 21.3 39.7 2.3 0.6 0.7 2.4 0.3 2.3 0.9 1.7 1.5 0.7 0.4 0.3 6.1 0.1 26.9 3.0 1.1 2.4 0.8 4.5 0.3 3.0 0.4 0.2 2.6 0.2 0.2 0.4 0.3 0.9 0.3 1.3 0.8 3.4 12.1 0.6 0.1 2.9 0.5 1.5 0.0 14.3 0.6 1.0 3.7 0.4 0.1 1.0 13.3 2.5 0.2 0.3 0.2 1.7 0.4 0.8 6.7 0.6 12.0 6.6 1.1 1.5 0.6 1.0 0.4 0.2 4.1 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 35.0 30.3 29.2 31.4 21.3 33.6 29.6 28.0 22.4 28.9 39.7 130.6 0.0 11.7 143.0 0.7 2.7 5.8 2.6 13.1 0.5 4.5 4.8 15.7 2.8 3.6 69.9 0.0 0.2 1.4 1.7 7.9 1.1 1.6 11.8 2.4 53.0 0.0 0.0 1.5 0.7 0.4 6.3 18.3 21.2 3.8 1.5 20.7 0.2 0.9 0.0 2.9 6.6 4.1 0.6 2.6 3.7 24.2 1.5 5.4 12.2 0.0 1.5 2.1 10.6 45.7 5.8 6.3 8.6 4.4 11.6 0.8 41.3 1.9 0.5 6.6 2.7 5.1 1.2 1.6 1.4 3.3 0.3 1.3 6.6 0.8 17.2 RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 22.5;Peritubular cells: 57.9;Sertoli cells: 98.6;Smooth muscle cells: 55.7" "Cancer enhanced" "Detected in all" "glioma: 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;CACO-2: 14.5;EFO-21: 22.7;NTERA-2: 9.9;SuSa: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (6.13e-3)" "unprognostic (1.06e-1)" "unprognostic (2.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-3)" "unprognostic (1.60e-1)" "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (1.76e-2)" "unprognostic (4.72e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.17e-4)" 27.9 3.9 32.9 5.1 36.8 0.0 15.7 30.8 24.4 49.8 8.5 35.6 3.6 61.6 27.9 19.2 54.7 13.2 53.4 26.0 38.4 6.9 1.1 38.4 3.3 39.4 57.4 16.5 2.4 1.8 7.0 17.0 38.0 52.5 6.7 3.3 8.0 76.4 37.1 12.1 9.4 33.0 38.8 9.6 7.7 15.6 66.1 0.9 8.4 20.6 1.7 40.2 33.5 32.6 0.1 0.1 0.2 0.0 0.6 5.0 0.2 0.0 0.5 0.0 0.0 14.5 0.1 0.0 22.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 17.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 36.8 30.8 24.4 26.0 38.4 39.4 57.4 38.0 38.8 66.1 32.6 7.4 0.0 0.0 22.5 0.0 1.5 3.9 0.0 0.0 0.3 2.0 5.6 16.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4.7 0.3 12.6 3.6 0.0 0.0 0.1 0.0 0.1 15.2 0.5 0.5 0.0 12.3 1.4 0.1 0.3 0.0 0.1 0.0 2.0 0.0 1.3 3.9 13.1 0.2 0.0 2.8 0.0 17.9 0.0 0.0 0.0 0.1 0.0 57.9 0.0 0.4 0.5 0.0 0.0 0.8 98.6 0.9 55.7 0.7 1.1 0.4 0.1 0.3 0.2 0.4 0.2 0.1 RBMS3 ENSG00000144642 "RNA binding motif single stranded interacting protein 3" Q6XE24 3 28574791-30010391 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 331.1;Inhibitory neurons: 655.9;Microglial cells: 1013.7;Oligodendrocyte precursor cells: 229.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 9 "dendritic cells: 3.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 20.7;WM-115: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034719 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034719: AB_10670172" "unprognostic (8.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.02e-1)" "unprognostic (7.08e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.90e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.25e-3)" "unprognostic (3.81e-2)" "unprognostic (8.48e-2)" "unprognostic (3.24e-4)" 15.8 8.6 6.5 2.1 7.2 0.1 12.2 9.5 5.8 9.9 12.0 8.1 1.4 6.2 6.7 3.1 9.8 6.7 14.3 2.1 21.4 5.1 3.7 12.6 2.7 12.6 15.7 11.6 2.0 4.9 3.2 10.4 9.0 6.4 2.6 0.4 4.7 8.7 6.4 3.8 4.0 4.5 6.3 6.6 4.3 2.2 11.1 5.5 15.3 10.8 1.7 8.1 7.3 2.6 2.2 0.2 10.2 0.1 19.6 12.5 0.0 5.7 3.6 5.9 6.8 0.0 0.4 0.0 6.1 20.7 1.8 0.2 0.5 3.8 10.9 0.0 1.1 5.9 8.7 0.0 19.9 0.1 0.0 11.8 2.6 10.5 12.3 8.4 7.9 0.0 0.0 0.0 7.4 0.0 0.1 0.0 0.3 0.0 0.4 0.4 7.5 0.0 2.2 0.0 0.0 19.4 13.7 0.0 0.7 4.6 0.0 0.0 17.1 11.1 11.6 13.5 11.7 0.0 0.0 0.8 1.5 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.9 0.3 0.0 6.5 7.2 9.5 5.8 2.1 21.4 12.6 15.7 9.0 6.3 11.1 2.6 100.9 118.6 18.8 331.1 0.6 8.3 25.5 23.0 2.2 0.4 2.7 19.8 16.2 31.5 21.3 9.2 0.0 16.4 5.9 0.0 0.0 5.3 35.1 2.8 7.0 54.4 0.0 0.0 20.7 1.2 3.0 96.8 2.0 4.6 5.1 19.8 129.9 1.9 2.8 0.0 655.9 0.0 6.1 30.3 14.1 18.8 159.7 2.7 7.2 1013.7 0.6 0.0 0.0 229.2 8.9 0.4 0.0 110.6 0.1 24.3 0.0 2.9 10.5 0.0 111.7 154.6 73.5 1.2 1.5 2.4 7.2 9.6 2.9 22.4 0.0 4.7 RIC8A "synembryn, synembryn-A" ENSG00000177963 "RIC8 guanine nucleotide exchange factor A" Q9NPQ8 11 207511-215113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041491, CAB046012" Approved Approved "Plasma membrane,Cytosol" NA NA 10000 "Cluster 44: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "CAB046012: AB_11129402, HPA041491: AB_2677510" "unprognostic (3.93e-2)" "unprognostic (8.69e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.60e-4)" "unprognostic (1.61e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.11e-6)" "unprognostic (2.13e-3)" "unprognostic (8.70e-2)" "unprognostic (7.68e-2)" "unprognostic (1.56e-1)" "unprognostic (8.35e-2)" "unprognostic (2.63e-3)" "unprognostic (5.35e-2)" "unprognostic (2.57e-1)" "unprognostic (2.14e-1)" "unprognostic (1.60e-1)" 39.2 39.6 43.0 34.8 43.6 40.6 37.4 42.1 48.5 41.2 46.6 46.3 29.5 44.2 41.8 43.1 41.1 30.6 42.9 45.4 43.7 36.5 37.8 37.6 37.6 43.5 44.4 39.7 39.3 34.2 38.1 34.1 44.2 39.0 30.8 24.8 34.4 40.3 32.8 39.5 38.1 49.4 43.4 41.6 38.1 44.0 44.0 41.6 33.7 28.3 41.8 45.9 36.6 45.0 176.3 83.9 66.8 66.7 89.7 73.4 46.3 124.1 99.2 166.0 114.2 72.6 121.1 69.6 50.5 189.0 125.7 93.4 76.4 131.4 92.0 84.5 76.7 39.4 59.5 67.8 72.3 66.5 125.8 80.6 114.3 103.2 92.6 85.2 82.8 72.8 68.7 66.0 129.3 71.1 79.6 52.6 61.1 74.0 103.0 74.0 66.0 47.5 96.9 45.6 69.2 62.2 96.3 107.1 67.1 63.9 76.1 52.8 93.4 109.2 96.5 40.4 117.3 72.6 117.6 67.8 107.7 59.5 83.5 72.9 41.1 88.3 79.0 49.7 78.2 64.4 70.1 69.0 43.7 55.1 59.9 60.6 59.9 73.0 61.0 35.8 65.0 86.6 43.0 43.6 42.1 48.5 45.4 43.7 43.5 44.4 44.2 43.4 44.0 45.0 30.9 16.0 21.1 10.7 28.7 17.7 20.5 38.6 17.1 28.1 22.5 27.2 23.5 28.6 25.5 25.8 10.4 41.4 46.5 26.3 27.4 53.1 20.2 15.9 24.3 27.2 20.3 27.4 9.4 44.2 60.0 30.4 23.0 19.7 17.7 28.8 27.8 17.1 46.8 32.0 8.4 19.2 30.5 27.4 11.5 17.3 30.7 27.5 28.4 11.2 38.9 43.4 30.9 5.0 7.8 71.6 25.5 39.9 35.2 26.5 29.9 23.0 20.8 33.1 19.7 20.7 35.4 93.2 62.5 20.9 19.5 32.4 34.8 30.2 25.0 17.0 RIN2 RASSF4 ENSG00000132669 "Ras and Rab interactor 2" Q8WYP3 20 19757606-20002457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 198.5;Microglial cells: 191.1;Oligodendrocyte precursor cells: 296.6;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034641 Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoli, Golgi apparatus" "HPA034641: AB_10671230" "unprognostic (8.23e-3)" "unprognostic (8.09e-3)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.12e-2)" "unprognostic (3.86e-2)" "unprognostic (1.61e-2)" "unprognostic (3.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.78e-3)" "unprognostic (2.49e-1)" "unprognostic (6.27e-2)" "prognostic favorable (8.34e-6)" "unprognostic (3.10e-1)" "unprognostic (2.08e-2)" "unprognostic (8.02e-3)" "unprognostic (3.63e-2)" 14.2 6.4 8.7 8.6 13.5 6.1 9.5 9.4 7.1 14.4 14.4 12.5 13.3 14.1 3.9 13.6 11.7 17.8 18.7 9.5 10.8 12.1 5.3 18.3 4.7 14.6 13.2 15.0 6.5 4.6 1.4 19.8 12.8 9.4 12.7 5.5 15.6 13.5 9.4 8.2 14.7 16.2 9.5 16.8 8.8 1.8 12.7 3.0 13.7 13.2 5.3 8.1 3.8 14.0 6.7 22.4 4.1 13.7 23.3 14.2 13.1 5.9 22.8 5.7 3.0 10.0 5.8 0.0 24.0 14.6 10.6 24.7 0.1 33.5 6.3 2.7 0.1 0.0 3.5 0.8 5.4 0.0 0.1 21.7 6.1 10.7 11.9 13.4 30.6 0.0 0.1 0.4 17.0 5.3 0.1 0.4 0.7 3.2 47.1 0.1 13.8 3.4 7.2 9.2 3.5 0.9 5.3 23.7 0.1 4.1 2.0 1.4 33.7 11.4 2.9 8.1 9.2 0.1 0.1 0.0 8.0 0.0 2.0 0.2 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 1.0 0.1 0.0 0.4 8.7 13.5 9.4 7.1 9.5 10.8 14.6 13.2 12.8 9.5 12.7 14.0 52.3 64.1 17.5 198.5 1.4 41.9 18.5 30.9 24.5 6.1 25.6 18.4 34.3 14.3 23.7 31.3 8.4 6.8 0.2 30.4 43.0 17.5 1.0 50.0 47.3 52.7 14.4 0.4 5.9 34.5 7.4 33.2 10.7 87.3 0.0 32.4 105.3 4.2 100.2 6.7 82.8 17.2 26.4 60.3 40.3 0.8 19.3 37.7 21.4 191.1 21.4 33.2 1.0 296.6 202.4 26.2 10.5 15.4 0.8 22.3 23.0 50.1 27.1 1.9 0.0 25.4 22.6 0.5 0.8 33.6 54.0 7.1 2.9 43.1 21.9 32.2 RNASE10 "RAH1, RNASE9" ENSG00000182545 "Ribonuclease A family member 10 (inactive)" Q5GAN6 14 20505537-20511169 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Fertilization" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "head and neck cancer: 2.0;testis cancer: 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 7.2;U-2 OS: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052593 Uncertain "Secreted - unknown location" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA052593: AB_2681878" "unprognostic (2.48e-3)" "unprognostic (2.22e-1)" "unprognostic (2.46e-2)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (5.91e-3)" "unprognostic (5.03e-3)" "unprognostic (5.58e-3)" "unprognostic (4.20e-2)" "unprognostic (3.04e-1)" "unprognostic (1.98e-3)" "unprognostic (1.11e-1)" "unprognostic (7.88e-4)" "unprognostic (1.58e-1)" "unprognostic (3.62e-1)" "unprognostic (8.76e-2)" "unprognostic (2.58e-1)" 2.1 1.8 3.2 1.6 3.0 1.1 0.4 2.8 4.3 0.5 2.8 0.7 1.6 2.0 1.1 1.1 1.1 0.6 0.4 3.2 2.4 0.9 0.8 1.6 0.8 3.8 3.0 1.1 0.4 0.4 0.5 0.8 3.2 1.2 0.4 0.5 0.9 0.7 2.0 2.5 1.7 0.5 1.8 1.3 1.1 1.9 3.1 0.5 0.7 0.2 0.4 0.7 0.5 5.2 4.4 2.0 0.9 1.9 0.2 0.4 2.8 0.2 0.4 0.1 0.3 0.9 1.2 0.5 1.3 0.5 0.6 2.3 0.0 0.3 0.1 1.7 0.7 0.0 1.5 0.6 0.5 0.1 2.0 0.7 1.5 0.1 2.3 0.4 1.0 0.7 1.0 2.3 0.0 1.2 0.7 1.1 0.5 0.6 0.2 3.3 0.3 2.6 0.7 1.8 1.1 1.4 7.2 1.7 0.9 0.9 1.6 0.7 0.4 0.7 10.8 0.9 0.8 2.2 0.9 0.2 0.8 0.6 0.9 1.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.3 0.0 0.0 3.2 3.0 2.8 4.3 3.2 2.4 3.8 3.0 3.2 1.8 3.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 309.4;Inhibitory neurons: 1518.9;Oligodendrocyte precursor cells: 348.3;Oligodendrocytes: 479.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Enhanced "Plasma membrane" NA NA 16000000 "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.89e-1)" "unprognostic (6.42e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (4.77e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (9.88e-4)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.77e-2)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-2)" 12.4 8.6 12.7 10.7 13.7 0.2 4.9 4.3 9.5 13.4 0.0 7.8 3.1 9.5 7.2 12.3 4.7 7.7 6.7 7.8 10.8 3.1 3.6 7.6 9.3 8.8 16.3 16.4 1.9 1.8 7.4 7.8 9.9 12.9 6.0 3.9 5.4 11.9 4.5 20.5 4.3 10.5 7.5 9.0 4.8 10.3 15.5 13.3 4.8 5.4 18.2 13.9 11.1 12.4 0.2 26.9 25.7 41.3 35.0 22.8 1.4 21.1 28.0 16.3 13.8 0.6 11.5 0.0 0.1 26.2 13.0 10.9 31.5 21.6 20.5 0.4 39.1 16.4 51.4 43.4 8.4 0.3 4.1 38.3 28.9 61.9 29.1 30.5 16.5 0.0 2.2 49.0 16.8 13.1 0.0 0.1 32.8 7.9 9.6 0.9 27.2 0.3 0.1 8.9 19.7 13.7 45.5 9.9 16.2 24.6 31.8 0.4 0.3 54.1 23.4 32.7 36.1 1.7 0.0 0.0 49.2 0.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 12.7 13.7 4.3 9.5 7.8 10.8 8.8 16.3 9.9 7.5 15.5 12.4 4.3 3.2 11.0 81.0 1.9 33.1 20.6 17.9 39.9 11.7 4.1 3.6 3.6 0.0 9.0 7.3 4.2 9.7 0.0 0.1 0.0 0.5 23.9 1.6 23.2 14.3 1.2 4.0 309.4 0.2 8.3 34.6 3.6 2.3 1.3 5.1 16.1 0.3 1.5 1.7 1518.9 1.4 22.4 2.6 10.0 65.9 19.9 1.5 14.2 51.5 1.9 5.7 0.0 348.3 479.3 0.2 5.1 24.5 1.3 20.5 4.9 0.4 2.9 1.0 13.1 24.7 16.8 2.7 7.0 30.3 33.8 5.6 0.9 71.1 2.6 52.7 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 SALL2 "Hsal2, KIAA0360, ZNF795" ENSG00000165821 "Spalt like transcription factor 2" Q9Y467 14 21521080-21537216 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.1" "Cell type enhanced" "Detected in many" "Astrocytes: 13.4;Bipolar cells: 13.9;Horizontal cells: 13.5;Muller glia cells: 11.2;Oligodendrocyte precursor cells: 10.6" "Cancer enhanced" "Detected in many" "glioma: 16.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 109.2;NTERA-2: 85.7;SuSa: 36.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004162 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Vesicles Nucleoplasm "HPA004162: AB_2667155" "unprognostic (5.73e-2)" "unprognostic (7.88e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (5.53e-2)" "unprognostic (4.58e-3)" "unprognostic (1.03e-1)" "unprognostic (1.15e-1)" "prognostic favorable (1.23e-4)" "unprognostic (7.98e-2)" "unprognostic (2.09e-1)" "unprognostic (5.28e-3)" "unprognostic (2.03e-1)" "unprognostic (3.75e-2)" "unprognostic (1.86e-1)" 3.9 5.4 40.2 1.4 37.7 0.2 5.5 43.2 31.0 13.1 16.6 13.3 1.7 13.5 6.3 2.9 12.7 3.2 5.4 29.4 43.7 6.2 0.9 4.5 1.7 41.3 45.2 17.2 4.3 20.6 27.0 1.2 36.9 7.0 2.1 16.9 3.1 9.2 1.5 2.6 6.7 9.5 39.2 2.8 6.0 1.6 49.1 6.5 10.5 2.8 1.7 8.7 6.3 28.7 0.1 2.4 109.2 24.2 1.9 1.6 0.0 2.1 2.7 7.1 7.2 2.3 1.2 0.1 2.2 3.2 3.1 0.2 24.5 2.7 10.0 2.0 12.5 0.0 0.7 2.2 3.2 0.0 0.1 7.3 0.9 3.4 0.0 18.4 2.2 10.9 16.6 0.0 6.2 2.1 16.0 0.1 85.7 0.1 0.5 14.3 2.3 0.0 8.3 11.6 30.4 17.3 0.0 0.6 0.3 36.2 9.2 0.2 0.0 0.9 11.5 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.5 1.1 0.0 0.1 0.0 0.5 0.5 0.1 40.2 37.7 43.2 31.0 29.4 43.7 41.3 45.2 36.9 39.2 49.1 28.7 0.8 3.2 3.6 13.4 0.0 0.6 0.6 1.1 8.0 13.9 3.4 2.8 0.9 2.8 1.5 5.5 8.4 0.1 0.2 0.0 1.9 1.8 0.3 0.5 3.2 1.0 0.0 0.4 2.5 0.0 0.1 3.9 0.0 0.4 0.0 7.2 2.5 0.1 0.1 13.5 9.3 0.0 4.1 0.0 0.3 0.7 5.0 0.2 0.0 0.0 0.0 11.2 0.0 10.6 2.6 0.3 0.0 6.0 0.2 0.4 0.0 0.8 0.0 2.8 0.0 3.9 3.0 0.0 0.5 1.0 0.6 0.1 0.8 3.9 0.0 0.1 SASH1 "dJ323M4.1, KIAA0790, SH3D6A" ENSG00000111961 "SAM and SH3 domain containing 1" O94885 6 148272304-148552048 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis, Palmoplantar keratoderma, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 194.8;Astrocytes: 426.7;Microglial cells: 179.9;Oligodendrocyte precursor cells: 186.5;Oligodendrocytes: 328.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "classical monocyte: 1.2;intermediate monocyte: 2.6;non-classical monocyte: 1.3" "Lineage enriched" "Detected in single" 26 "monocytes: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 198.0;ASC TERT1: 74.7;fHDF/TERT166: 73.4;HUVEC TERT2: 75.0;WM-115: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029947, HPA029949" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "HPA029947: AB_10598915, HPA029949: AB_10602280" "unprognostic (9.71e-2)" "unprognostic (4.74e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.55e-2)" "unprognostic (4.79e-3)" "unprognostic (6.69e-2)" "unprognostic (4.76e-2)" "unprognostic (2.06e-1)" "unprognostic (8.65e-3)" "unprognostic (9.94e-2)" "unprognostic (2.96e-1)" "unprognostic (2.13e-3)" "unprognostic (5.45e-2)" "unprognostic (3.53e-1)" "unprognostic (8.04e-3)" "unprognostic (1.54e-1)" 76.1 6.1 45.5 6.6 62.5 0.3 47.6 58.2 35.4 24.5 10.3 18.1 6.8 13.6 5.1 45.2 15.9 19.7 17.0 40.0 43.0 15.0 9.3 26.5 6.2 72.1 60.0 6.5 9.5 14.2 5.1 30.3 59.4 11.6 9.8 15.4 19.8 9.2 17.9 31.0 11.8 16.1 49.1 13.7 9.5 4.6 65.1 5.1 39.0 22.5 7.8 13.8 27.9 59.3 4.8 2.9 23.6 7.9 198.0 74.7 3.9 27.3 65.6 20.2 30.7 6.2 5.7 0.0 14.1 73.4 10.1 5.7 7.3 6.7 16.9 0.0 5.3 0.0 13.6 5.7 6.1 0.0 1.3 35.1 6.8 30.6 8.3 8.3 75.0 0.0 0.4 0.1 19.1 5.5 0.0 0.0 6.9 2.6 3.8 0.0 16.8 0.2 15.1 15.1 0.9 0.0 8.4 30.8 21.5 6.1 2.4 14.0 65.6 19.7 4.0 63.1 5.9 0.0 0.0 0.0 31.6 0.0 95.6 0.0 1.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 45.5 62.5 58.2 35.4 40.0 43.0 72.1 60.0 59.4 49.1 65.1 59.3 194.8 16.0 21.7 426.7 0.6 41.0 6.2 5.1 29.6 21.9 17.7 24.0 18.5 5.7 18.3 46.0 6.2 20.6 0.8 4.4 7.9 3.1 0.8 45.3 36.2 104.7 4.8 0.0 16.4 2.4 59.5 66.5 8.2 40.1 2.5 2.3 60.3 8.1 8.8 3.3 120.7 5.3 10.2 42.4 18.5 1.6 18.3 15.6 42.7 179.9 4.9 100.4 0.0 186.5 328.6 1.5 2.9 28.2 1.3 6.4 2.3 15.0 15.5 4.7 78.9 49.9 73.2 0.5 3.7 46.3 33.0 32.7 1.6 3.1 7.2 7.4 SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.5" "Cell type enhanced" "Detected in many" "Astrocytes: 238.6;Collecting duct cells: 66.2;Cytotrophoblasts: 45.8;Muller glia cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 179.9;HeLa: 203.2;HUVEC TERT2: 140.1;U-2 OS: 120.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA029861: AB_2673225, HPA047386: AB_2680024" "unprognostic (2.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.68e-3)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.17e-1)" "unprognostic (4.31e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.78e-2)" "unprognostic (4.95e-2)" "unprognostic (6.31e-3)" "unprognostic (6.03e-3)" 23.8 7.2 53.4 15.7 58.6 0.0 17.6 55.6 57.8 58.7 29.9 34.5 5.0 87.9 9.5 23.7 86.8 30.5 13.9 50.3 68.1 11.3 3.9 15.2 13.4 136.5 89.5 13.8 4.1 1.5 9.6 19.5 79.2 25.6 8.5 8.8 35.7 66.5 2.6 17.5 15.4 68.1 80.3 2.8 14.7 3.2 79.2 15.9 51.3 8.0 23.0 31.1 20.7 71.4 1.8 61.0 9.4 0.2 49.9 179.9 40.0 23.8 38.2 25.8 19.1 22.7 15.8 0.0 52.7 50.3 21.1 44.5 0.1 44.9 12.7 0.2 5.1 17.8 203.2 0.8 5.3 0.0 0.1 75.6 2.9 40.2 2.3 35.0 140.1 4.6 0.0 0.2 15.0 11.8 0.2 0.1 12.3 0.0 22.3 0.1 0.0 0.3 8.2 27.4 0.2 5.9 5.7 32.0 0.1 4.8 31.1 0.5 49.9 20.7 120.1 77.2 12.8 0.1 0.1 0.2 35.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 58.6 55.6 57.8 50.3 68.1 136.5 89.5 79.2 80.3 79.2 71.4 2.3 0.0 0.5 238.6 0.0 3.6 16.2 4.8 14.8 1.0 12.6 19.8 2.2 8.6 6.0 66.2 0.0 45.8 0.6 0.1 0.0 0.4 2.9 3.8 10.1 6.4 0.0 0.0 38.4 0.8 20.4 25.1 1.5 2.0 0.0 5.3 15.4 0.4 4.7 0.0 30.4 0.1 0.0 0.3 2.1 1.3 15.8 0.5 17.8 21.5 0.6 52.4 0.0 19.1 18.1 2.2 0.1 6.4 0.0 5.4 0.0 0.0 6.5 1.5 6.6 1.8 14.7 0.2 1.5 6.2 3.8 8.2 0.3 1.9 0.3 10.3 SEC22C "MGC13261, MGC5373, SEC22L3" ENSG00000093183 "SEC22 homolog C, vesicle trafficking protein" Q9BRL7 3 42547969-42601080 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031242 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Nucleoplasm "HPA031242: " "unprognostic (1.68e-1)" "unprognostic (4.86e-2)" "unprognostic (1.01e-1)" "unprognostic (2.67e-1)" "unprognostic (9.37e-3)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.15e-1)" "unprognostic (3.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (2.57e-1)" "prognostic favorable (1.35e-7)" "unprognostic (2.59e-1)" "unprognostic (3.30e-1)" "unprognostic (7.51e-2)" "unprognostic (1.41e-3)" 35.7 23.4 37.3 14.1 40.8 36.5 33.2 39.1 46.8 28.2 33.8 31.1 31.9 29.8 27.4 17.2 27.2 18.9 24.3 34.1 38.0 26.2 16.4 33.1 19.0 41.4 40.3 29.3 29.6 26.4 26.6 19.3 42.0 37.3 15.6 25.6 23.3 25.9 22.2 19.4 32.6 26.3 37.5 20.4 28.3 27.5 39.2 18.2 24.2 26.1 16.4 25.7 23.1 48.1 24.0 22.2 35.9 30.5 72.4 68.1 7.6 43.8 46.7 46.1 47.9 15.5 37.9 24.5 17.6 50.1 28.2 12.6 24.1 39.8 40.7 32.8 28.5 41.7 40.0 21.0 55.4 19.2 39.5 38.3 53.1 51.4 62.5 46.5 51.1 38.7 37.0 46.5 45.8 16.6 27.1 22.3 19.8 16.0 31.9 11.7 21.4 22.9 40.6 21.1 18.5 27.8 30.9 28.0 34.5 26.5 48.4 20.9 42.9 35.1 27.8 63.8 43.1 36.8 55.6 23.5 41.7 26.6 34.0 11.7 11.5 22.0 13.2 9.0 19.6 11.5 17.6 16.3 10.8 9.4 14.9 13.2 7.1 10.2 9.3 11.3 16.3 10.1 37.3 40.8 39.1 46.8 34.1 38.0 41.4 40.3 42.0 37.5 39.2 48.1 31.4 25.6 27.6 27.1 23.2 15.0 18.3 25.3 25.0 16.6 31.6 29.6 18.8 24.3 17.2 11.0 29.2 20.5 28.1 1.9 41.1 29.7 61.2 17.5 19.5 30.5 9.0 48.2 18.9 32.9 20.3 31.8 21.9 12.7 49.4 25.1 32.2 14.5 31.3 26.9 18.4 4.9 32.6 19.0 14.4 15.0 32.6 17.6 40.9 21.5 35.5 39.2 24.7 12.5 44.1 28.8 1.0 42.9 23.0 24.0 36.9 29.6 19.4 39.9 39.5 26.6 31.1 96.9 49.8 11.3 10.2 10.5 34.6 20.3 6.6 9.4 SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 110.2;Bipolar cells: 75.7;Excitatory neurons: 84.9;Oligodendrocyte precursor cells: 250.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 3.9;SK-BR-3: 19.9;U-2 OS: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029419: AB_10602090, HPA063804: AB_2685127" "unprognostic (4.42e-2)" "unprognostic (1.48e-2)" "unprognostic (7.82e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-1)" "unprognostic (4.27e-2)" "unprognostic (9.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.25e-1)" "unprognostic (1.42e-1)" "unprognostic (9.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-6)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" 1.2 0.1 3.1 0.2 2.8 0.0 2.8 0.6 2.3 1.8 0.1 2.1 0.6 1.9 0.3 1.2 0.6 2.3 0.1 5.0 5.3 0.1 0.1 2.2 0.0 1.6 4.3 0.1 0.4 0.0 0.2 0.2 1.3 4.3 1.7 3.9 2.2 3.3 0.2 0.5 1.2 1.1 3.2 0.0 1.3 0.0 4.3 1.7 0.6 1.0 0.1 3.2 0.7 3.7 0.2 1.1 0.2 0.0 0.5 3.1 0.0 0.0 0.2 0.2 0.3 0.0 0.3 0.0 0.0 0.0 0.5 0.0 3.4 0.0 1.3 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.9 0.0 0.0 0.5 0.4 1.1 0.0 2.0 0.0 0.0 0.8 0.1 0.0 0.0 19.9 0.0 3.2 1.6 0.0 0.0 0.7 6.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 2.8 0.6 2.3 5.0 5.3 1.6 4.3 1.3 3.2 4.3 3.7 10.5 176.3 110.2 2.9 0.2 1.1 1.3 1.6 0.0 75.7 19.0 7.5 1.7 18.6 43.2 1.8 0.0 0.8 0.2 0.1 0.0 3.9 1.1 3.8 1.2 10.7 0.0 0.0 84.9 1.1 0.4 21.3 3.1 9.3 24.0 0.2 0.0 0.3 0.1 0.0 12.3 0.0 4.1 1.0 2.1 0.0 0.9 3.6 1.8 1.0 1.0 29.6 0.0 250.3 6.0 6.2 0.0 0.0 0.3 2.6 0.1 0.5 35.7 3.6 0.0 0.8 1.0 0.3 0.6 0.3 0.4 0.3 2.8 0.0 0.0 2.5 SEMA4C "Semacl1, Semaf, SEMAI" ENSG00000168758 "Semaphorin 4C" Q9C0C4 2 96859718-96870757 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 137.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "BEWO: 298.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011090 Approved NA NA 700000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA011090: AB_2185705" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (7.10e-2)" "unprognostic (4.46e-2)" "unprognostic (1.57e-2)" "unprognostic (4.20e-3)" "unprognostic (3.08e-1)" "unprognostic (2.16e-1)" "unprognostic (3.56e-2)" "unprognostic (1.82e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (9.50e-7)" "unprognostic (4.78e-3)" "unprognostic (3.09e-1)" "unprognostic (7.31e-2)" "unprognostic (4.08e-1)" 21.3 8.9 11.5 11.3 24.2 3.0 17.7 16.8 19.9 29.0 0.5 42.1 7.4 37.2 6.0 14.0 33.3 15.3 20.2 11.8 15.6 14.9 13.3 14.4 9.8 24.9 21.1 23.1 9.4 7.1 10.2 41.8 21.0 20.8 5.7 7.0 16.5 20.6 7.5 15.9 14.6 19.3 18.7 28.5 15.1 2.7 19.0 6.5 12.3 13.4 5.3 32.3 22.3 39.1 8.0 11.7 35.6 39.7 8.4 10.5 298.5 13.9 17.4 13.4 13.5 11.8 13.3 0.0 22.3 8.5 13.3 8.1 10.2 6.9 6.5 15.2 11.8 5.4 10.5 22.2 19.2 2.2 13.7 16.1 5.4 12.3 10.4 14.9 9.9 2.6 36.5 11.6 12.7 41.0 0.1 17.4 49.1 0.4 10.6 12.5 20.0 13.8 4.8 17.1 22.4 32.4 11.2 24.6 60.8 27.6 8.7 21.4 3.1 21.9 27.3 30.9 14.6 0.2 1.0 0.1 10.6 17.2 37.1 0.5 0.0 0.0 0.6 0.2 0.8 0.0 0.2 0.4 0.0 0.0 0.4 0.1 0.0 1.4 1.5 0.8 0.3 0.4 11.5 24.2 16.8 19.9 11.8 15.6 24.9 21.1 21.0 18.7 19.0 39.1 28.1 0.0 10.3 15.3 1.1 11.5 7.9 7.6 18.2 32.2 9.9 8.3 6.9 12.8 8.6 5.5 10.4 46.8 9.7 1.8 1.9 9.7 0.5 7.4 15.8 26.6 5.4 2.1 7.2 5.0 137.3 17.3 3.1 11.6 1.3 10.2 23.9 9.8 7.9 15.2 4.1 5.7 6.1 4.4 6.1 1.5 13.4 9.2 21.4 18.7 3.2 23.6 12.3 4.5 35.5 10.5 1.2 9.1 3.6 9.4 0.1 0.8 7.4 38.8 19.7 11.4 24.1 0.6 4.2 13.0 10.2 45.0 9.5 4.9 3.9 4.8 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 SESTD1 "DKFZp434O0515, Solo" ENSG00000187231 "SEC14 and spectrin domain containing 1" Q86VW0 2 179101678-179264832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 175.5;Horizontal cells: 301.2;Oligodendrocytes: 311.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058236, HPA077408" Approved Enhanced "Intermediate filaments" NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Intermediate filaments" "HPA058236: AB_2732619, HPA077408: AB_2732344" "unprognostic (2.76e-1)" "unprognostic (3.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (9.47e-2)" "unprognostic (1.64e-1)" "unprognostic (2.59e-1)" "unprognostic (7.91e-3)" "unprognostic (9.21e-2)" "prognostic favorable (2.78e-11)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.57e-2)" 15.4 2.4 11.6 3.2 17.2 4.7 11.2 12.5 11.4 6.2 0.9 7.1 2.0 5.8 3.9 4.5 4.5 6.4 6.3 8.2 10.3 6.7 3.4 9.2 3.4 16.2 13.5 4.5 3.3 3.9 3.6 6.8 14.6 4.2 3.8 7.5 11.0 4.6 3.6 4.5 5.4 8.1 15.1 3.5 5.5 9.0 18.1 2.9 3.7 5.8 4.9 10.0 4.8 23.6 0.0 2.1 25.5 4.6 45.2 19.5 13.5 9.0 3.7 3.7 6.3 4.6 6.0 4.5 11.7 8.7 4.5 4.2 11.0 5.1 6.8 3.3 2.9 5.5 11.2 12.3 3.5 3.1 2.3 14.6 2.1 5.7 14.3 8.9 15.2 4.6 0.8 2.3 6.4 3.1 7.2 0.3 6.6 4.7 2.6 10.3 16.8 2.9 10.0 23.2 5.6 9.5 8.0 3.4 2.5 18.7 0.5 3.4 26.7 12.3 6.2 6.3 4.7 1.3 0.0 11.0 6.2 1.2 3.7 0.0 0.9 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.4 1.5 0.0 0.0 0.1 0.3 1.6 0.0 0.0 0.2 11.6 17.2 12.5 11.4 8.2 10.3 16.2 13.5 14.6 15.1 18.1 23.6 46.2 109.0 29.9 53.2 30.6 9.8 24.7 19.1 7.4 31.3 30.4 15.6 15.3 28.6 32.9 12.9 18.8 10.7 5.7 11.9 17.6 31.3 9.8 61.3 33.1 32.1 25.0 7.2 110.8 27.7 73.4 65.1 13.7 175.5 0.0 23.1 21.4 9.6 12.3 301.2 147.9 7.3 14.2 28.7 43.4 7.3 12.2 37.2 14.2 89.0 21.9 33.4 5.2 86.5 311.1 33.3 13.3 30.5 4.7 67.7 22.5 39.1 42.8 10.4 19.7 43.7 29.2 34.9 66.0 10.2 10.1 18.1 5.7 9.8 9.7 119.9 SH3PXD2A "FISH, KIAA0418, SH3MD1" ENSG00000107957 "SH3 and PX domains 2A" Q5TCZ1 10 103594027-103855543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.8;BJ hTERT+: 84.8;fHDF/TERT166: 68.5;HSkMC: 64.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037922, HPA037923" Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA037922: AB_10697088, HPA037923: AB_10672612" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.95e-2)" "unprognostic (3.00e-2)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.80e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.83e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (1.25e-1)" "unprognostic (2.59e-1)" "unprognostic (5.78e-3)" "unprognostic (2.62e-2)" 18.9 8.5 49.2 11.5 45.1 1.4 14.5 25.6 38.6 49.0 2.9 27.3 5.7 31.2 7.2 30.3 25.7 17.4 16.9 32.8 32.2 7.0 23.0 17.2 4.7 38.1 40.9 29.5 8.4 1.2 14.0 16.3 39.1 18.5 13.4 17.1 14.1 13.9 19.0 29.4 14.3 26.7 44.8 13.3 13.0 3.0 42.4 6.7 9.2 14.3 5.9 21.5 31.9 64.7 1.3 5.3 13.7 16.5 48.1 86.8 7.3 39.5 84.8 13.1 12.4 0.5 0.4 0.0 7.7 68.5 1.5 13.3 0.8 35.5 11.6 2.3 14.3 16.5 21.8 19.2 31.0 8.2 4.5 64.5 27.2 20.1 43.5 9.8 8.8 17.9 6.1 9.7 16.6 0.5 0.2 8.0 5.8 11.4 2.5 6.8 5.2 1.0 5.5 4.8 10.2 5.5 3.8 0.9 19.9 7.4 0.2 5.8 15.4 11.0 7.6 14.3 17.7 10.9 24.1 0.5 10.7 11.1 42.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 49.2 45.1 25.6 38.6 32.8 32.2 38.1 40.9 39.1 44.8 42.4 64.7 22.6 6.4 45.4 10.1 7.6 91.0 26.4 45.2 56.3 46.1 9.3 13.5 22.9 22.8 37.8 3.7 27.1 12.1 3.4 48.1 0.0 5.3 3.2 7.7 109.9 23.9 37.1 10.5 59.5 0.6 32.0 42.2 12.8 11.5 17.7 21.8 23.9 87.3 13.0 89.2 96.6 74.8 22.4 7.6 34.9 7.3 105.9 7.7 33.8 15.0 19.0 1.7 2.1 5.0 117.2 6.2 27.0 80.5 7.9 32.1 4.1 1.3 21.6 35.7 39.5 32.1 55.6 1.9 3.7 37.5 38.1 4.7 6.8 15.0 22.7 61.1 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHISAL1 KIAA1644 ENSG00000138944 "Shisa like 1" Q3SXP7 22 44243665-44312951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.2;endometrium 1: 33.6;smooth muscle: 29.3" "Cell type enriched" "Detected in single" 6 "Endometrial stromal cells: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SiHa: 36.2;U-2197: 80.8;U-87 MG: 46.3;WM-115: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051178 Uncertain Approved Vesicles,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "HPA051178: AB_2681374" "unprognostic (4.07e-3)" "unprognostic (9.01e-2)" "unprognostic (1.83e-1)" "unprognostic (1.14e-1)" "unprognostic (6.54e-2)" "unprognostic (1.22e-1)" "unprognostic (7.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.10e-3)" "unprognostic (1.93e-3)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (1.51e-7)" "unprognostic (1.48e-2)" "unprognostic (2.41e-1)" "unprognostic (1.99e-4)" "unprognostic (1.10e-4)" 1.0 1.8 18.6 1.2 17.2 0.0 0.2 0.0 21.4 16.6 0.0 18.7 1.9 33.6 0.4 1.6 4.5 3.1 0.9 18.0 15.3 0.5 0.1 0.3 0.4 10.8 17.8 1.0 0.8 0.1 2.6 0.5 2.4 3.7 2.0 5.6 0.3 11.0 0.0 0.7 2.4 29.3 0.3 0.1 1.6 1.1 43.2 2.6 0.4 0.1 0.7 11.9 5.2 2.8 0.0 0.3 3.5 1.2 0.0 0.0 0.0 1.0 2.3 2.4 1.4 0.0 0.0 0.0 0.0 2.3 14.5 0.0 5.0 0.3 0.3 0.0 2.3 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.4 4.5 1.8 11.2 0.5 0.0 0.0 0.1 0.1 0.0 0.4 0.0 3.3 0.0 0.8 0.0 0.0 0.1 0.0 0.0 12.9 0.0 36.2 0.1 0.2 0.4 0.0 0.3 0.1 13.1 2.0 80.8 0.5 0.0 0.0 0.0 46.3 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 17.2 0.0 21.4 18.0 15.3 10.8 17.8 2.4 0.3 43.2 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 SLC12A9 CIP1 ENSG00000146828 "Solute carrier family 12 member 9" Q9BXP2 7 100826820-100867010 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 90.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-BR-3: 61.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067536 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA067536: AB_2732768" "unprognostic (6.53e-2)" "unprognostic (3.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.11e-3)" "unprognostic (3.47e-2)" "unprognostic (2.37e-2)" "unprognostic (8.38e-3)" "prognostic favorable (5.97e-4)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.00e-4)" "unprognostic (2.47e-2)" "unprognostic (1.03e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.52e-2)" "unprognostic (6.00e-2)" "unprognostic (6.74e-3)" "unprognostic (6.38e-2)" 6.9 8.1 7.4 8.7 11.2 7.6 6.3 10.7 10.8 8.3 6.5 8.3 7.8 8.2 1.2 7.3 6.7 9.5 4.2 7.3 8.7 7.4 6.8 8.2 7.3 12.5 10.6 6.7 10.5 6.3 3.6 14.0 11.4 8.0 5.6 0.7 7.4 6.4 2.6 7.9 8.3 6.7 10.1 14.1 7.0 2.7 9.3 5.9 5.8 3.1 3.8 9.2 6.1 13.1 16.1 12.4 4.2 33.9 12.4 7.3 42.2 7.9 15.1 11.7 16.6 17.7 26.7 11.5 25.1 15.0 18.8 17.3 7.3 17.6 3.1 12.3 12.1 4.4 13.8 12.6 15.1 5.4 18.0 18.0 9.9 9.3 9.4 9.5 23.2 9.1 10.5 6.1 16.8 49.8 5.7 25.5 8.3 33.3 24.6 13.3 4.2 17.9 11.6 14.3 7.0 15.8 8.7 61.7 16.7 7.0 7.7 19.1 14.5 14.4 14.3 23.8 14.4 3.2 13.7 4.0 10.2 18.0 17.4 0.0 1.5 0.0 0.2 1.8 0.3 0.6 0.1 0.1 2.4 0.6 0.2 0.1 1.4 0.2 1.9 1.2 0.3 0.9 7.4 11.2 10.7 10.8 7.3 8.7 12.5 10.6 11.4 10.1 9.3 13.1 10.6 3.2 16.1 3.9 12.3 11.0 12.0 6.9 10.8 6.6 12.6 11.0 2.1 11.5 10.1 18.4 2.1 90.0 21.7 14.1 0.0 12.7 0.9 5.6 9.1 13.6 11.4 1.7 2.0 13.4 28.2 10.2 18.3 9.5 1.3 14.7 15.7 6.9 31.2 6.7 2.6 13.6 10.2 23.9 18.3 0.7 9.0 27.2 8.8 3.7 24.6 18.7 8.2 6.0 5.8 14.9 23.7 6.4 9.7 8.3 14.7 10.9 4.8 6.7 13.1 9.4 7.3 1.7 7.8 12.9 11.4 50.2 13.4 17.2 19.6 9.6 SLC35B4 "FLJ14697, YEA4" ENSG00000205060 "Solute carrier family 35 member B4" Q969S0 7 134289332-134316930 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 95.2;Syncytiotrophoblasts: 83.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049779 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA049779: AB_2680878" "unprognostic (1.84e-1)" "unprognostic (1.94e-2)" "unprognostic (7.19e-2)" "unprognostic (2.49e-2)" "unprognostic (1.77e-3)" "unprognostic (3.47e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (1.57e-1)" "unprognostic (3.32e-2)" "unprognostic (6.88e-3)" "unprognostic (1.86e-1)" "unprognostic (2.24e-3)" "unprognostic (3.18e-2)" "unprognostic (2.86e-1)" "unprognostic (9.81e-2)" "unprognostic (1.00e-1)" 5.1 6.4 8.8 5.2 8.7 1.9 3.3 9.8 8.5 4.0 7.6 4.0 2.9 6.0 6.3 3.3 4.4 3.9 2.5 8.5 8.9 10.4 8.5 3.3 4.5 8.0 8.5 6.4 2.6 4.6 4.2 11.8 7.7 5.2 3.5 12.3 2.3 6.1 2.5 3.1 4.1 7.1 7.7 4.2 3.5 4.7 10.1 4.8 3.4 2.9 4.8 4.0 2.8 8.7 6.8 22.5 19.3 29.0 18.4 15.3 9.9 16.9 14.1 14.7 12.4 8.7 6.3 22.9 5.6 18.3 19.2 7.2 29.0 15.0 24.3 14.5 21.4 15.5 12.9 11.6 13.6 22.1 13.4 13.6 6.3 17.7 14.9 11.0 14.4 15.6 15.2 8.2 22.2 6.1 19.7 16.1 40.0 7.0 20.0 14.1 17.0 11.2 8.3 8.3 6.7 39.5 15.1 5.0 19.0 16.0 2.7 12.4 16.1 19.0 6.2 11.5 16.9 26.9 39.9 25.9 34.0 20.5 22.4 0.7 1.5 0.3 1.6 2.1 2.5 1.3 1.5 2.1 3.1 1.4 1.4 2.1 0.1 1.9 1.7 2.1 1.7 1.4 8.8 8.7 9.8 8.5 8.5 8.9 8.0 8.5 7.7 7.7 10.1 8.7 7.2 9.6 5.4 22.9 10.2 2.2 5.7 10.7 6.2 52.6 4.9 3.4 6.9 11.5 8.5 1.8 45.9 95.2 3.7 2.2 11.7 8.1 2.4 5.3 15.2 11.8 4.2 8.8 33.4 5.3 27.8 13.3 14.8 6.5 1.3 27.8 7.5 15.1 20.9 42.1 36.6 5.7 22.4 9.3 3.9 3.4 11.1 11.9 5.4 14.0 8.4 16.2 14.4 24.1 24.3 9.0 4.9 12.4 9.2 4.9 7.0 13.9 6.2 21.6 6.6 10.0 10.0 10.8 24.0 9.3 3.3 83.2 10.7 31.3 4.1 3.7 SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "prostate: 306.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 19.9;granulocytes: 119.2;Oligodendrocytes: 47.1;Prostatic glandular cells: 67.2" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.5" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.5" "Cell line enriched" "Detected in many" 29 "HMC-1: 834.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" 1.4 3.6 6.7 3.2 19.5 0.8 1.6 17.6 13.4 3.7 1.9 4.8 4.6 1.7 0.5 1.6 2.1 3.8 1.5 8.0 10.3 2.1 11.2 3.4 2.7 25.1 17.3 2.7 0.8 0.3 4.7 0.5 21.8 306.4 3.2 0.1 2.8 0.6 5.6 1.5 4.8 1.0 12.6 12.4 16.8 1.4 16.6 0.5 1.0 2.3 0.8 2.8 1.1 44.7 9.7 3.0 2.8 2.7 0.0 0.1 2.2 1.3 0.3 3.3 2.7 7.1 18.0 2.7 4.6 0.3 3.0 3.5 1.6 3.3 0.5 3.9 2.9 29.0 0.6 2.0 1.9 5.0 834.2 0.3 1.1 2.3 0.0 2.2 9.4 4.5 4.9 1.7 1.4 2.3 0.8 8.5 12.2 16.7 10.7 1.0 4.1 1.5 3.7 13.7 1.2 2.9 1.5 20.6 3.9 2.3 4.7 1.4 9.6 1.4 9.5 3.5 7.1 0.4 0.6 0.4 1.8 1.5 7.1 40.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 19.5 17.6 13.4 8.0 10.3 25.1 17.3 21.8 12.6 16.6 44.7 0.2 0.0 3.2 1.0 4.0 0.0 1.0 0.6 0.0 0.4 1.5 1.8 2.0 2.8 1.0 1.8 0.0 0.5 0.1 5.7 0.0 1.7 0.2 1.9 0.2 1.7 0.0 3.4 0.2 0.5 0.1 0.7 19.9 0.2 119.2 0.2 0.7 6.6 1.9 0.0 0.3 6.9 2.0 1.0 0.3 0.4 1.8 2.0 0.0 0.0 0.6 0.1 0.0 2.0 47.1 3.9 8.0 1.5 0.3 67.2 0.9 1.8 3.2 0.1 6.6 0.1 0.8 0.0 2.6 0.4 0.1 0.0 0.9 0.2 6.7 0.9 SLC7A10 asc-1 ENSG00000130876 "Solute carrier family 7 member 10" Q9NS82 19 33208664-33225850 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 31.8;brain: 12.7;breast: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 40.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.9;HHSteC: 1.1;HSkMC: 1.6;THP-1: 3.9;U-2 OS: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041884, HPA057036" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli" "HPA041884: AB_10794494, HPA057036: AB_2683317" "unprognostic (1.85e-2)" "unprognostic (1.69e-3)" "unprognostic (2.79e-2)" "unprognostic (1.79e-6)" "unprognostic (1.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (4.98e-3)" "unprognostic (4.64e-2)" "unprognostic (1.96e-1)" "unprognostic (3.28e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-2)" "unprognostic (1.34e-3)" "unprognostic (8.91e-2)" "unprognostic (3.47e-1)" "unprognostic (2.18e-2)" 31.8 0.3 7.9 0.1 9.7 0.0 12.7 10.1 11.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.3 9.2 0.5 0.0 0.0 0.2 8.5 12.4 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.5 0.8 0.0 0.1 0.2 0.5 0.0 6.0 0.0 0.1 0.5 12.7 0.0 0.5 0.4 0.3 0.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 9.7 10.1 11.1 7.3 9.2 8.5 12.4 8.4 6.0 12.7 5.1 0.1 0.0 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 2.4 0.0 9.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLCO3A1 "OATP-D, OATP3A1, SLC21A11" ENSG00000176463 "Solute carrier organic anion transporter family member 3A1" Q9UIG8 15 91853708-92172435 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 625.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 63.1;HaCaT: 95.5;HMC-1: 55.3;RPMI-8226: 44.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066327 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA066327: AB_2732743" "unprognostic (1.05e-3)" "prognostic favorable (8.61e-4)" "unprognostic (5.40e-2)" "prognostic unfavorable (6.57e-6)" "unprognostic (1.03e-1)" "unprognostic (7.39e-2)" "unprognostic (2.16e-1)" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-2)" "unprognostic (1.49e-2)" "unprognostic (2.64e-2)" "unprognostic (3.06e-2)" "unprognostic (1.86e-1)" "unprognostic (7.17e-2)" "unprognostic (1.62e-2)" 11.7 6.2 19.3 6.8 29.5 9.6 8.6 33.7 23.0 8.4 24.1 4.0 1.8 5.3 3.3 10.6 6.9 6.3 26.4 20.3 20.2 10.6 2.9 13.8 6.3 30.2 29.6 4.2 3.0 15.7 6.7 1.0 27.8 4.3 3.4 1.5 4.7 6.2 5.8 15.7 4.2 5.0 22.5 11.1 4.6 17.9 26.1 2.6 10.6 9.6 6.2 8.6 10.8 39.5 10.1 12.3 13.9 0.2 20.9 12.6 0.2 4.0 3.4 1.6 0.4 0.0 63.1 12.1 5.3 1.3 9.1 95.5 2.7 6.3 0.2 8.8 0.4 27.8 20.9 0.0 0.9 0.6 55.3 5.7 6.7 2.9 7.3 5.4 0.0 3.6 0.0 0.1 0.0 1.8 0.0 5.1 3.7 0.2 1.7 0.0 1.1 44.0 13.4 10.0 2.0 3.3 10.5 0.9 0.1 2.0 0.1 8.5 0.0 3.3 4.7 0.0 10.3 25.5 16.0 11.7 4.2 16.9 6.0 4.3 2.4 6.9 1.4 2.0 1.1 0.2 1.5 1.7 1.6 0.0 0.5 0.6 7.5 0.3 1.7 0.0 2.7 0.6 19.3 29.5 33.7 23.0 20.3 20.2 30.2 29.6 27.8 22.5 26.1 39.5 53.5 48.1 32.0 17.0 4.3 39.0 29.3 14.2 22.8 28.1 3.1 13.0 44.0 24.3 16.4 51.5 4.2 0.0 33.1 6.2 1.9 26.6 105.6 15.8 29.0 26.2 37.8 6.1 89.5 8.7 0.1 22.9 0.5 36.2 22.8 94.9 34.6 0.8 4.6 0.0 149.4 7.2 8.2 24.7 95.2 38.5 5.0 34.0 10.6 56.2 43.6 5.2 25.7 20.6 625.8 8.4 11.1 3.0 17.3 41.5 0.0 0.4 22.1 3.1 39.5 17.4 62.0 69.5 11.9 22.6 60.1 0.0 23.3 0.8 7.9 38.2 SLCO4A1 "OATP-E, OATP4A1, SLC21A12" ENSG00000101187 "Solute carrier organic anion transporter family member 4A1" Q96BD0 20 62642503-62685785 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 57.2" "Cell type enhanced" "Detected in many" "Adipocytes: 61.8;Extravillous trophoblasts: 239.4;Melanocytes: 60.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 197.2;RPTEC TERT1: 193.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.7" "Low region specificity" "Detected in some" "HPA030669, HPA030670" Uncertain Supported "Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Cell Junctions" "HPA030669: AB_10601163, HPA030670: AB_10670033" "unprognostic (8.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.41e-1)" "unprognostic (2.46e-3)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "unprognostic (2.84e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (3.49e-3)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (2.84e-3)" "unprognostic (9.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.25e-1)" 32.4 5.6 26.2 1.8 24.0 1.3 23.4 24.2 35.7 11.1 19.6 9.8 1.2 8.7 0.3 16.7 13.1 1.8 48.6 23.9 25.4 35.8 5.0 57.2 2.4 26.5 24.8 6.5 4.9 3.8 2.9 4.7 28.0 5.9 1.8 21.5 8.5 1.0 18.8 25.6 9.2 0.8 25.7 6.6 13.5 2.1 31.6 1.1 8.6 5.6 3.2 12.0 16.8 24.9 14.8 19.1 0.8 10.8 2.5 2.1 26.5 4.7 16.6 14.1 5.4 32.0 14.9 17.8 44.2 0.5 9.6 22.0 16.4 1.0 5.4 2.1 9.6 21.7 22.1 23.8 0.1 16.6 6.7 0.0 6.5 0.3 6.2 4.2 2.5 10.7 17.1 4.6 0.0 14.8 17.2 63.9 5.4 74.1 197.2 30.6 1.1 26.2 193.9 14.2 17.4 25.1 4.1 4.4 15.7 6.5 1.0 7.5 2.8 0.4 10.5 7.0 27.2 9.2 15.9 11.1 38.1 24.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.9 0.7 0.2 0.1 0.0 0.0 0.0 0.0 1.6 0.2 26.2 24.0 24.2 35.7 23.9 25.4 26.5 24.8 28.0 25.7 31.6 24.9 61.8 3.2 1.3 1.3 13.1 27.3 1.4 19.8 1.2 14.1 1.2 0.8 4.4 1.5 5.9 25.8 31.3 2.1 3.7 7.5 0.0 5.9 0.3 8.7 3.6 40.3 0.0 2.1 7.9 2.5 239.4 4.3 20.9 35.6 0.0 0.0 14.6 0.6 5.5 0.0 6.6 8.4 2.0 9.7 33.5 0.7 0.3 11.9 60.5 3.7 0.0 6.1 0.0 1.5 0.3 11.8 1.9 0.7 19.1 3.5 0.8 9.6 1.3 43.2 0.0 1.9 2.9 0.2 3.0 1.1 16.1 23.5 5.6 0.1 7.5 11.0 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4430.9;Endothelial cells: 2372.1;Peritubular cells: 2523.5;Sertoli cells: 4674.1;Skeletal myocytes: 2379.0;Smooth muscle cells: 2781.9" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 24.9;SuSa: 31.4;U-266/70: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Enhanced "Secreted in other tissues" NA NA 630000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" 755.6 129.5 664.6 124.5 810.9 0.5 532.1 612.4 1058.4 732.7 580.4 624.3 125.1 1244.5 443.8 308.1 754.5 487.9 600.2 744.6 723.5 72.5 25.0 481.1 99.1 655.7 730.9 286.8 91.8 128.0 197.8 315.4 663.4 584.2 187.5 95.2 228.3 999.2 244.8 130.2 280.1 1191.2 774.7 157.9 347.7 97.5 694.8 103.2 369.9 594.7 100.0 488.0 466.4 681.2 0.7 0.0 24.9 0.3 0.2 0.1 2.6 0.1 0.1 0.0 0.0 0.0 0.1 0.4 1.8 0.0 0.0 1.4 2.4 0.0 0.0 1.7 0.0 0.3 1.1 0.4 1.1 0.3 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.5 0.2 3.5 0.6 0.0 0.0 0.3 0.4 1.2 0.0 0.1 0.8 1.6 0.1 0.2 0.1 31.4 0.4 0.5 0.0 0.2 0.3 1.5 0.2 9.1 1.4 0.6 3.4 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 664.6 810.9 612.4 1058.4 744.6 723.5 655.7 730.9 663.4 774.7 694.8 681.2 4430.9 12.8 56.4 1155.7 6.2 46.3 187.2 0.6 59.7 10.7 24.4 251.6 334.2 4.3 43.3 7.3 2.1 2.2 8.6 0.0 13.7 0.8 11.8 34.9 935.8 2372.1 0.0 32.0 382.3 0.4 3.2 1413.1 6.1 46.7 7.6 1.4 899.5 9.1 9.2 3.3 450.1 0.0 0.0 5.3 55.2 47.0 659.5 31.6 56.9 261.4 0.0 179.4 0.0 210.6 53.8 0.1 0.0 2523.5 25.2 50.4 0.0 24.6 7.4 34.4 4674.1 2379.0 2781.9 5.7 7.9 56.8 39.9 2.5 26.9 38.8 0.0 124.2 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SPRED1 "FLJ33903, PPP1R147" ENSG00000166068 "Sprouty related EVH1 domain containing 1" Q7Z699 15 38252836-38357249 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 173.7;Excitatory neurons: 163.4;Microglial cells: 199.5;Oligodendrocyte precursor cells: 277.9;Oligodendrocytes: 146.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 4 "monocytes: 1.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042193, HPA061805" Approved Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA042193: AB_10794079, HPA061805: AB_2684617" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.46e-1)" "prognostic favorable (7.08e-4)" "unprognostic (1.20e-1)" "unprognostic (2.38e-1)" "unprognostic (1.21e-3)" "unprognostic (5.71e-2)" "unprognostic (3.84e-2)" "unprognostic (2.81e-3)" "unprognostic (9.27e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (7.37e-5)" "prognostic unfavorable (8.29e-5)" "unprognostic (6.04e-2)" "unprognostic (5.77e-2)" "unprognostic (1.01e-1)" 12.7 8.2 16.0 8.8 20.3 0.7 10.9 14.7 20.6 11.5 7.1 11.4 8.2 10.9 5.7 6.1 6.9 12.8 7.3 16.5 16.3 9.1 5.6 17.4 7.1 18.9 19.6 7.9 4.5 6.8 4.0 14.0 16.2 7.2 10.9 7.5 5.6 8.6 2.6 6.1 8.4 9.5 15.6 9.0 10.3 8.2 17.9 4.4 31.1 8.0 4.9 13.2 6.8 18.3 11.0 8.2 59.0 11.3 21.4 39.0 4.8 25.1 24.7 13.1 16.2 7.6 8.7 0.1 9.0 21.7 9.5 8.6 6.2 17.3 26.2 1.5 2.0 13.0 5.2 7.3 26.3 7.1 34.6 25.5 8.5 25.5 23.4 33.6 10.7 6.5 11.7 12.1 32.2 2.9 2.6 5.2 12.0 37.6 22.0 0.0 13.3 7.3 21.2 16.9 2.9 13.0 7.2 3.5 26.7 9.3 2.8 1.7 18.2 32.0 15.7 19.7 15.4 10.1 7.1 16.7 22.5 2.8 52.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 16.0 20.3 14.7 20.6 16.5 16.3 18.9 19.6 16.2 15.6 17.9 18.3 26.4 99.3 26.9 173.7 2.5 28.3 24.6 9.4 45.5 12.6 17.2 20.8 7.2 28.6 12.6 1.8 6.2 1.3 1.5 15.7 1.9 9.5 40.3 12.0 29.4 28.2 6.7 4.6 163.4 4.9 0.9 33.0 17.3 14.8 41.8 5.4 26.7 4.1 57.8 5.0 100.0 21.2 6.1 48.2 24.6 9.6 21.8 38.7 28.4 199.5 7.3 25.4 0.0 277.9 146.9 15.1 7.8 30.5 1.6 12.7 6.6 12.8 11.4 5.2 6.6 44.4 44.1 8.0 5.0 18.1 9.7 1.4 2.4 21.4 15.3 14.7 SPRY2 hSPRY2 ENSG00000136158 "Sprouty RTK signaling antagonist 2" O43597 13 80335976-80341126 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 267.9;SK-MEL-30: 156.9;WM-115: 136.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037205, HPA042198" Approved Supported "Actin filaments,Microtubules" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments, Microtubules" "CAB037205: AB_261923, HPA042198: AB_2677896" "unprognostic (9.37e-3)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (9.12e-3)" "unprognostic (3.80e-2)" "unprognostic (8.99e-2)" "unprognostic (3.95e-3)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (4.28e-2)" "unprognostic (1.56e-2)" "unprognostic (9.89e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.86e-2)" 69.6 24.1 37.4 11.8 38.0 29.5 66.2 57.6 42.9 31.0 27.7 40.4 17.6 29.3 15.3 20.0 46.7 30.1 50.9 38.5 36.0 21.1 27.8 31.5 8.9 50.2 40.4 16.9 27.4 10.2 17.3 13.9 40.2 26.2 27.3 34.2 34.8 18.9 39.1 26.5 25.4 23.5 42.0 30.8 25.9 4.1 39.7 11.3 27.1 41.4 4.9 27.0 30.8 43.4 1.8 7.6 84.2 267.9 108.4 70.6 5.8 69.3 31.1 15.3 18.2 34.9 10.3 0.0 11.6 28.5 10.6 6.7 4.8 13.9 17.0 0.1 15.3 12.0 4.5 8.9 24.9 63.4 4.8 31.8 14.6 26.1 63.3 95.6 29.9 13.0 4.4 0.3 35.0 1.5 8.6 28.8 33.7 23.6 19.6 25.6 112.0 0.2 28.8 11.7 1.0 46.7 5.7 3.1 156.9 32.9 6.3 56.0 44.3 14.3 5.6 30.3 13.6 0.1 0.1 0.0 97.6 23.9 136.9 0.0 0.0 2.1 0.3 0.0 0.1 0.4 0.0 0.8 0.9 0.0 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.1 37.4 38.0 57.6 42.9 38.5 36.0 50.2 40.4 40.2 42.0 39.7 43.4 48.5 25.6 29.3 59.4 2.9 43.5 38.0 12.5 53.5 5.9 12.4 21.3 20.5 18.6 6.3 1.8 6.2 8.7 12.1 33.4 5.9 11.3 0.3 25.2 17.6 22.3 12.0 8.4 22.1 8.0 2.9 65.9 11.2 41.7 16.4 7.2 32.5 17.0 10.9 8.4 15.3 36.1 4.1 27.3 10.7 1.5 29.5 12.2 14.2 15.9 0.8 68.5 3.1 39.7 17.6 18.0 33.7 5.7 1.7 23.1 7.2 8.3 4.8 23.3 26.3 57.7 67.6 0.1 1.5 16.2 29.1 9.6 11.1 8.5 27.6 11.9 SPTAN1 ENSG00000197694 "Spectrin alpha, non-erythrocytic 1" Q13813 9 128552558-128633662 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 296.6;Cone photoreceptor cells: 310.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004581, HPA007927" Enhanced Approved Vesicles,Microtubules NA NA 1600000 "Cluster 13: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Microtubules" "CAB004581: AB_671135, HPA007927: AB_1857435" "unprognostic (1.46e-2)" "unprognostic (2.73e-2)" "unprognostic (1.56e-1)" "unprognostic (9.06e-2)" "unprognostic (3.24e-1)" "unprognostic (4.02e-2)" "unprognostic (2.56e-3)" "unprognostic (2.20e-1)" "unprognostic (1.81e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-1)" "unprognostic (1.36e-1)" "prognostic favorable (1.84e-12)" "unprognostic (2.94e-2)" "unprognostic (1.60e-1)" "unprognostic (4.18e-3)" "unprognostic (2.19e-3)" 48.8 31.4 81.7 38.6 85.0 28.1 36.6 54.4 99.7 39.4 0.4 47.3 24.7 57.1 32.9 36.8 54.0 32.5 65.7 90.9 43.5 34.6 22.8 55.1 38.5 142.7 49.6 51.6 24.0 47.1 32.5 57.1 155.0 32.7 36.3 103.1 31.9 46.5 23.9 69.4 34.9 58.8 65.6 44.3 31.1 44.9 61.5 45.4 38.4 22.3 38.0 40.0 36.4 55.3 108.1 116.9 75.2 83.4 107.6 121.0 61.5 90.2 75.2 99.4 74.1 167.3 74.6 94.3 78.3 137.0 69.8 193.3 80.7 90.4 61.1 53.2 47.9 15.9 324.4 94.4 61.3 70.9 51.0 58.3 71.6 166.3 55.8 83.9 134.4 87.2 9.1 107.6 98.6 74.6 136.3 29.5 96.1 125.9 72.1 91.0 90.2 59.7 80.2 91.1 58.1 91.1 296.1 40.3 42.9 91.8 70.0 19.8 232.5 68.5 102.2 100.0 71.2 65.3 82.6 51.8 83.5 31.5 65.9 3.3 1.6 3.9 9.7 1.3 13.5 6.3 12.4 9.2 2.4 5.8 7.6 7.9 1.5 7.1 1.2 3.0 15.3 5.8 81.7 85.0 54.4 99.7 90.9 43.5 142.7 49.6 155.0 65.6 61.5 55.3 144.9 70.5 27.5 123.7 56.3 37.3 27.8 34.3 25.6 296.6 69.8 83.2 68.5 68.6 33.9 101.2 310.6 27.5 112.6 145.4 7.9 67.6 18.0 108.2 71.4 103.8 56.9 13.7 159.5 59.2 16.0 77.8 76.5 87.5 12.0 47.9 96.8 36.2 29.2 124.5 183.8 54.1 30.5 22.2 29.4 40.5 85.1 32.8 35.6 74.9 24.4 97.7 48.4 87.4 17.4 102.2 93.0 94.8 70.5 45.9 62.4 22.8 71.3 156.5 26.3 53.0 60.0 33.0 44.5 43.7 45.5 18.2 95.4 22.0 73.6 65.7 SPTBN1 ENSG00000115306 "Spectrin beta, non-erythrocytic 1" Q01082 2 54456317-54671446 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 615.4;Peritubular cells: 663.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012685, HPA013149" Supported Approved "Golgi apparatus" NA Yes 1500000 "Cluster 39: Non-specific - mRNA processing" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA012685: AB_1857433, HPA013149: AB_1857434" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (3.00e-2)" "unprognostic (3.25e-1)" "unprognostic (4.09e-2)" "unprognostic (7.95e-2)" "unprognostic (9.24e-2)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.26e-2)" "unprognostic (7.25e-2)" "prognostic favorable (2.59e-5)" "unprognostic (2.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.68e-3)" "unprognostic (5.18e-3)" 187.3 70.9 210.6 34.7 205.1 37.6 78.7 97.4 166.1 54.1 94.2 62.8 32.7 52.0 36.3 41.7 56.2 69.2 135.9 156.2 99.7 65.3 83.8 131.6 28.9 141.2 154.4 73.2 45.5 129.2 27.8 97.4 120.4 43.8 52.4 56.0 55.1 74.4 54.0 39.4 46.8 59.9 134.8 58.7 55.6 32.6 214.6 29.3 72.8 87.2 30.0 45.6 38.6 163.6 96.5 150.5 60.4 57.2 234.7 158.8 74.8 40.2 82.3 63.7 61.4 101.7 66.6 0.4 112.1 142.0 55.1 110.9 85.1 128.0 66.0 0.8 35.6 43.7 118.4 166.2 97.7 59.7 24.4 62.3 64.8 193.8 119.7 77.6 151.6 95.1 50.0 64.0 86.1 21.6 105.0 14.5 66.3 129.6 70.2 116.2 95.0 37.2 92.2 120.6 36.3 113.3 121.5 39.5 88.1 58.9 19.6 9.9 235.2 89.9 79.0 110.2 58.2 62.8 42.8 32.7 98.1 17.7 163.7 2.3 0.4 2.8 3.7 0.0 3.9 3.7 3.4 3.6 1.3 3.5 5.0 3.6 0.6 5.2 0.0 1.1 3.2 3.1 210.6 205.1 97.4 166.1 156.2 99.7 141.2 154.4 120.4 134.8 214.6 163.6 615.4 407.1 124.6 233.4 45.7 83.1 50.0 64.7 42.7 94.4 60.8 58.0 262.9 144.4 100.6 145.3 73.0 28.3 31.7 343.6 7.9 223.7 12.1 140.4 80.3 426.4 83.1 21.5 231.3 121.9 42.0 271.6 139.7 115.7 35.4 68.2 228.5 184.6 14.2 141.3 195.4 135.5 77.3 17.7 47.0 31.5 503.2 16.6 147.7 294.2 9.7 131.9 36.0 154.8 283.1 243.3 109.9 663.5 76.3 75.6 142.8 44.1 187.3 93.6 164.3 340.3 171.9 54.7 53.3 79.7 68.2 11.1 49.2 56.6 151.9 88.1 ST6GALNAC6 "SIAT7F, ST6GALNACVI" ENSG00000160408 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" Q969X2 9 127885321-127905408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 258.8;Intestinal goblet cells: 100.6;Paneth cells: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "NK-cells: 23.7;T-cells: 25.6" "Cell line enhanced" "Detected in all" "ASC diff: 157.1" "Low region specificity" "Detected in all" HPA018890 Approved "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018890: AB_1857531" "unprognostic (2.27e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (5.71e-2)" "unprognostic (1.36e-1)" "unprognostic (4.84e-2)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.24e-3)" "unprognostic (3.31e-2)" "unprognostic (3.29e-1)" "unprognostic (1.10e-2)" "unprognostic (9.85e-2)" "unprognostic (3.46e-2)" "unprognostic (2.67e-2)" 95.8 37.4 155.5 21.4 156.0 17.7 68.7 129.5 177.8 48.7 120.2 75.5 9.5 48.6 50.0 35.0 67.2 28.4 61.3 165.6 130.9 50.1 63.5 66.7 27.5 133.4 137.2 83.0 52.8 32.4 26.0 22.0 128.3 40.2 126.4 16.0 28.3 41.5 46.0 37.4 35.2 38.0 128.3 64.1 43.9 17.6 140.6 14.9 32.5 40.2 23.1 56.6 42.6 134.6 12.0 9.2 18.9 36.9 157.1 91.9 7.4 29.7 69.6 43.7 35.9 16.3 10.0 13.8 13.4 68.1 28.4 21.9 25.6 23.7 19.0 50.9 14.0 13.4 19.0 16.7 48.1 3.3 18.9 94.9 27.5 34.0 15.1 61.6 40.9 11.9 12.2 14.6 54.9 9.9 8.4 19.3 9.1 12.3 17.5 24.6 27.0 14.3 32.2 2.4 13.1 21.3 21.4 8.8 7.6 12.3 9.3 29.0 26.7 27.6 16.3 30.5 15.8 18.4 9.8 21.5 24.5 4.1 8.7 3.3 1.2 0.1 25.3 1.9 18.5 5.3 16.5 18.8 1.8 3.9 10.0 13.7 0.6 23.7 5.0 2.1 25.6 12.4 155.5 156.0 129.5 177.8 165.6 130.9 133.4 137.2 128.3 128.3 140.6 134.6 1.3 3.2 4.3 13.1 10.5 23.2 17.2 15.7 9.1 22.0 0.9 0.6 8.7 8.6 9.5 0.0 6.2 4.3 11.7 258.8 0.0 0.3 2.5 0.8 1.7 20.6 38.5 26.1 11.5 0.4 7.7 26.6 3.6 1.4 7.0 0.2 46.8 28.5 11.6 25.2 10.7 100.6 18.3 10.0 35.6 9.4 66.5 4.1 24.9 8.4 3.2 58.7 46.4 5.5 3.8 0.3 178.3 60.9 8.9 20.5 0.3 0.0 16.1 8.5 85.5 41.2 31.9 1.4 4.8 10.3 26.9 3.6 17.7 0.5 84.7 18.6 ST8SIA6 SIAT8F ENSG00000148488 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" P61647 10 17315421-17454595 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;lung: 5.9" "Cell type enriched" "Detected in some" 5 "Microglial cells: 137.7" "Cancer enhanced" "Detected in some" "breast cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "HMC-1: 208.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011635, HPA072708" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA011635: AB_2194921, HPA072708: " "unprognostic (4.86e-3)" "unprognostic (7.01e-2)" "unprognostic (5.85e-3)" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (2.32e-1)" "unprognostic (3.23e-2)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (1.07e-3)" 0.7 0.3 5.8 0.4 4.1 1.8 5.2 3.2 3.6 0.3 2.4 0.6 0.3 0.4 4.6 0.5 0.3 0.5 3.4 2.9 3.3 0.8 1.0 5.9 0.2 5.4 10.5 0.4 0.2 0.0 0.3 1.1 4.6 1.5 0.4 0.4 0.6 0.2 0.2 1.0 0.4 0.3 3.6 0.6 0.3 0.3 8.0 0.3 0.4 0.8 0.4 0.2 0.4 4.3 0.2 0.2 0.1 1.7 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.6 0.6 0.0 0.1 0.3 0.3 0.5 0.1 0.0 0.0 0.4 0.2 25.9 0.4 0.5 0.0 0.0 208.0 0.1 0.0 0.2 0.1 1.8 0.0 0.3 4.6 0.4 2.5 1.9 1.1 0.4 2.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 9.3 0.2 1.1 0.0 3.6 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.1 1.7 0.5 0.5 0.5 0.1 0.2 0.1 0.3 0.3 0.2 0.3 0.3 0.4 1.0 0.7 0.3 0.2 0.8 0.2 5.8 4.1 3.2 3.6 2.9 3.3 5.4 10.5 4.6 3.6 8.0 4.3 0.6 0.0 0.0 2.6 0.1 0.6 0.1 0.2 0.0 0.0 10.0 3.9 0.8 0.0 0.2 0.0 0.0 0.0 5.5 1.2 0.0 0.0 0.5 0.1 0.0 10.9 0.0 25.5 3.0 0.0 0.0 0.3 0.0 0.8 10.2 2.8 26.7 0.0 0.1 0.0 4.4 0.0 0.0 0.9 0.0 0.6 0.0 0.2 8.8 137.7 0.2 0.0 8.2 1.5 1.1 0.1 0.1 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.3 0.0 0.0 0.0 2.4 0.1 0.0 0.1 STARD13 "ARHGAP37, DLC2, GT650, LINC00464" ENSG00000133121 "StAR related lipid transfer domain containing 13" Q9Y3M8 13 33103137-33350630 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 212.5;Excitatory neurons: 120.7;Inhibitory neurons: 135.6;Microglial cells: 167.7;Oligodendrocyte precursor cells: 212.6;Oligodendrocytes: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 50.2;TIME: 36.0;WM-115: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039535, HPA058867" Supported NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039535: AB_10965929, HPA058867: AB_2683839" "unprognostic (7.42e-2)" "unprognostic (6.71e-2)" "unprognostic (1.99e-1)" "unprognostic (4.99e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (7.13e-3)" "unprognostic (3.42e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (5.29e-2)" 16.0 10.9 10.0 5.6 13.2 0.3 11.1 8.7 10.9 16.6 13.4 28.0 4.8 14.8 5.3 7.2 10.4 10.8 12.5 12.6 8.1 8.4 6.1 12.5 2.5 11.1 11.9 7.2 10.8 16.9 4.3 24.6 9.6 9.0 6.8 1.8 6.4 8.1 5.4 5.3 7.0 15.7 8.4 7.4 11.2 2.8 11.7 1.4 20.4 6.3 1.4 14.0 9.6 13.6 11.4 1.6 3.4 2.4 6.8 16.0 0.6 21.2 26.2 17.4 10.8 0.9 4.0 0.1 2.8 10.2 10.7 10.4 1.5 7.5 22.0 10.0 3.6 5.2 3.9 5.2 5.7 0.0 4.6 13.3 4.3 19.7 24.0 9.7 17.1 0.1 0.0 1.7 50.2 3.3 0.0 0.0 2.2 1.2 5.7 0.2 16.6 0.1 10.6 3.2 0.1 5.5 3.2 8.0 2.6 3.0 18.5 4.7 36.0 8.7 9.3 22.0 11.0 2.9 0.0 0.1 7.0 0.1 40.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 10.0 13.2 8.7 10.9 12.6 8.1 11.1 11.9 9.6 8.4 11.7 13.6 30.5 28.9 15.1 212.5 0.1 2.4 2.8 1.1 4.0 5.3 8.6 5.1 19.8 7.2 2.0 9.2 0.0 9.4 4.2 11.8 0.0 7.7 1.2 5.5 26.6 18.4 6.7 0.0 120.7 2.2 3.7 18.8 10.7 6.4 5.1 6.2 17.9 10.7 16.7 5.0 135.6 4.4 0.0 8.8 6.8 1.4 7.2 10.8 14.2 167.7 0.8 1.1 0.0 212.6 470.9 5.5 4.3 7.5 4.7 4.4 3.4 2.1 6.3 0.4 13.1 15.6 33.1 0.1 0.3 1.0 2.3 7.5 0.6 31.1 5.4 1.5 STARD8 "ARHGAP38, KIAA0189" ENSG00000130052 "StAR related lipid transfer domain containing 8" Q92502 X 68647666-68725842 "Metabolic proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.9;Endothelial cells: 26.5;Hepatic stellate cells: 18.5;Kupffer cells: 13.7;Langerhans cells: 14.9;Macrophages: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "classical monocyte: 1.6;intermediate monocyte: 3.2;myeloid DC: 3.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 18 "dendritic cells: 3.4;monocytes: 4.7" "Cell line enhanced" "Detected in many" "HEL: 16.0;K-562: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060788 Uncertain NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA060788: AB_2684365" "unprognostic (2.00e-1)" "unprognostic (8.98e-2)" "unprognostic (1.56e-3)" "unprognostic (4.94e-3)" "unprognostic (1.73e-1)" "unprognostic (2.61e-2)" "unprognostic (2.77e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (5.09e-3)" "unprognostic (9.72e-2)" "unprognostic (9.58e-2)" "unprognostic (5.19e-3)" "unprognostic (4.89e-3)" "unprognostic (9.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.07e-2)" 13.4 4.4 8.1 6.0 6.9 3.4 10.3 6.4 6.8 6.3 5.7 4.0 1.4 7.1 4.7 3.4 8.9 5.2 12.5 6.3 6.3 14.7 6.5 20.7 4.1 13.5 7.5 3.3 5.1 2.6 8.9 8.8 8.1 9.2 1.5 0.6 2.7 8.5 6.8 2.8 4.3 6.1 8.2 11.1 4.2 0.8 8.4 1.6 10.3 6.5 1.9 6.6 4.5 6.6 0.0 1.8 2.8 1.4 0.0 0.0 2.1 3.8 7.9 2.1 1.6 0.0 0.4 0.0 9.6 1.6 0.2 0.0 0.8 0.0 3.5 0.0 0.5 16.0 1.4 0.2 0.3 0.0 0.0 1.3 0.0 5.4 0.0 6.1 9.9 0.0 20.4 0.0 5.3 0.8 0.0 9.5 1.6 0.0 0.3 0.0 10.1 5.4 9.5 0.0 0.0 0.7 0.1 0.9 0.3 5.6 1.3 2.2 7.0 9.6 4.0 3.1 3.7 0.0 0.0 0.0 7.2 6.6 5.7 0.0 1.6 0.0 0.0 3.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.7 0.1 0.0 1.8 8.1 6.9 6.4 6.8 6.3 6.3 13.5 7.5 8.1 8.2 8.4 6.6 27.9 0.0 6.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.2 0.3 8.5 0.0 1.8 0.0 0.0 0.3 0.1 0.0 1.9 0.0 0.1 1.2 1.6 26.5 0.0 2.1 0.3 0.0 0.2 3.0 0.5 1.1 7.0 0.3 18.5 6.5 3.6 0.0 0.8 0.0 0.0 13.7 14.9 0.0 0.3 13.9 0.0 9.4 2.4 0.3 0.0 0.5 0.5 0.8 0.0 0.0 0.9 0.1 0.0 2.4 2.2 0.4 0.0 2.8 3.5 0.1 0.2 0.2 1.4 0.1 0.6 0.2 0.0 0.1 SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 61.3;Sertoli cells: 32.9;Smooth muscle cells: 29.0" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.1;HUVEC TERT2: 78.5;LHCN-M2: 30.4;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" 4.6 1.4 2.9 0.9 3.0 0.1 1.9 2.2 4.6 6.3 4.4 1.7 0.8 4.6 2.2 1.3 5.2 5.5 1.5 3.1 4.4 1.5 0.5 1.7 2.3 3.4 3.4 3.8 0.6 1.0 0.8 0.2 3.4 1.3 1.2 0.6 0.7 6.3 1.6 1.9 1.9 4.8 3.8 2.5 1.8 2.1 4.7 0.1 3.2 3.3 5.3 1.5 2.4 3.5 0.0 1.1 1.2 0.7 1.7 0.2 0.1 9.6 3.4 31.1 10.5 0.1 0.0 0.0 8.8 2.5 9.5 0.1 13.7 4.5 12.9 0.3 15.3 0.0 2.0 0.0 0.2 0.1 0.1 1.3 2.4 19.9 3.9 15.2 78.5 0.0 0.0 0.1 30.4 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.0 1.0 0.1 0.1 2.5 0.7 1.8 1.9 31.3 0.0 14.4 1.2 4.7 0.0 0.7 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 3.0 2.2 4.6 3.1 4.4 3.4 3.4 3.4 3.8 4.7 3.5 0.1 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 2.2 0.5 0.0 0.0 15.4 0.0 0.1 1.4 0.0 0.9 0.0 0.2 0.4 0.0 0.0 3.3 10.5 0.0 0.0 2.1 2.0 0.3 0.0 0.1 1.8 0.0 0.0 0.5 0.0 61.3 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 32.9 3.6 29.0 0.1 2.6 0.1 1.0 0.0 0.2 0.1 0.0 0.1 TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 7 "Inhibitory neurons: 83.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" 6.2 0.3 1.7 0.7 3.6 0.0 5.0 0.0 7.2 4.9 0.0 1.0 0.2 3.0 0.7 1.2 2.9 1.1 0.1 0.6 3.7 0.7 0.0 0.8 1.3 2.2 4.3 0.6 0.1 0.2 0.1 0.5 10.0 1.5 0.5 1.0 1.5 1.0 0.3 4.0 0.7 2.7 0.8 0.0 0.5 0.0 2.5 1.1 0.5 0.3 1.3 2.0 2.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.6 0.0 7.2 0.6 3.7 2.2 4.3 10.0 0.8 2.5 0.9 7.6 0.0 0.0 1.0 0.0 2.5 0.0 0.0 0.0 1.0 0.3 0.3 1.4 0.0 0.0 0.0 2.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 11.8 0.0 0.0 4.5 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 83.2 0.2 0.0 0.0 2.6 0.9 0.0 0.0 7.2 2.8 0.0 0.4 0.0 3.5 4.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 3.3 0.0 0.2 0.2 0.0 0.0 0.1 1.8 0.1 0.1 0.0 0.0 0.2 TANC1 "KIAA1728, ROLSB" ENSG00000115183 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1" Q9C0D5 2 158968640-159232659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 212.0;Microglial cells: 159.3;Oligodendrocyte precursor cells: 193.5;Oligodendrocytes: 223.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036750 Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA036750: AB_10670241" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" "unprognostic (8.91e-2)" "unprognostic (2.43e-2)" "unprognostic (3.96e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.43e-2)" "unprognostic (3.94e-2)" "unprognostic (1.69e-2)" "unprognostic (1.20e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" 9.1 5.9 9.7 3.9 14.0 0.2 7.8 15.8 7.5 10.2 8.1 9.2 6.4 10.9 2.0 12.7 5.8 7.5 22.1 13.0 15.8 6.6 4.4 12.6 3.3 18.4 13.6 6.3 5.9 5.9 3.5 13.4 18.1 7.8 7.0 12.0 7.1 4.4 2.7 20.5 6.5 12.9 11.9 5.0 5.9 1.9 21.1 3.6 10.8 4.3 4.8 8.6 6.8 20.0 8.7 7.4 18.4 14.3 16.7 7.1 9.0 6.6 13.9 6.6 10.4 8.0 9.5 0.0 22.6 21.2 5.0 18.7 5.9 26.1 8.4 0.0 13.7 5.6 11.8 1.5 19.7 0.7 14.3 11.0 21.3 12.4 23.1 30.1 35.8 8.5 1.4 39.8 11.1 3.9 5.5 0.0 2.4 9.8 6.7 0.7 10.0 12.9 15.2 34.9 2.8 18.9 14.5 6.6 34.9 11.4 7.2 5.6 33.8 14.7 8.6 3.1 6.1 19.7 14.5 0.0 8.2 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 14.0 15.8 7.5 13.0 15.8 18.4 13.6 18.1 11.9 21.1 20.0 42.1 28.9 17.1 34.9 0.2 48.9 13.5 21.7 46.7 30.1 19.3 16.9 64.7 15.7 23.5 11.0 6.2 2.9 0.9 18.9 3.9 13.3 1.1 11.1 12.1 48.3 0.0 4.2 9.9 12.5 3.8 16.0 33.1 11.7 17.2 47.6 35.3 8.7 2.0 212.0 54.7 16.6 10.2 2.8 10.3 1.7 10.5 1.7 24.9 159.3 0.6 48.6 1.0 193.5 223.7 13.4 22.7 4.9 1.6 14.4 10.5 4.9 12.5 4.9 13.1 11.6 27.5 0.5 2.1 38.6 42.1 2.1 2.5 14.6 14.9 17.3 TBC1D16 "FLJ20748, MGC25062" ENSG00000167291 "TBC1 domain family member 16" Q8TBP0 17 79932343-80035872 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 307.9" "Cancer enhanced" "Detected in all" "melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.3" "Lineage enhanced" "Detected in single" "monocytes: 2.3" "Cell line enhanced" "Detected in many" "ASC diff: 179.1;SK-MEL-30: 192.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024482, HPA065839" Approved Approved "Intermediate filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Intermediate filaments" "HPA024482: AB_1857790, HPA065839: AB_2685566" "unprognostic (4.53e-3)" "unprognostic (1.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.06e-2)" "unprognostic (4.92e-2)" "unprognostic (7.21e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (5.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-3)" "unprognostic (3.99e-3)" 37.3 8.1 17.6 8.7 24.8 0.9 18.4 24.4 14.6 10.4 5.3 8.0 7.9 12.4 11.5 10.1 12.9 9.5 10.7 10.6 15.2 27.7 7.4 9.0 7.8 18.0 22.7 11.7 15.7 12.9 7.0 7.5 16.0 17.7 5.9 7.6 29.4 10.8 5.1 17.3 9.0 10.5 13.0 7.3 8.4 4.1 38.9 4.0 10.1 6.7 3.5 8.6 6.2 17.4 30.3 28.2 43.1 50.8 179.1 93.7 8.2 17.3 17.1 10.7 12.0 53.6 10.3 0.1 11.9 29.2 20.3 9.4 45.8 16.2 8.2 1.5 21.5 0.0 13.3 25.1 30.5 0.6 4.1 106.1 28.1 23.2 16.7 17.1 45.9 19.8 7.2 19.6 20.2 18.4 8.1 2.7 51.8 39.3 15.4 25.4 27.2 17.5 12.6 36.5 43.8 56.8 15.4 42.5 192.4 26.7 27.9 13.6 31.3 37.1 26.1 29.5 15.3 59.9 11.4 3.3 15.9 11.2 47.8 0.0 0.1 0.0 0.0 1.9 0.2 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.0 2.3 0.0 0.0 0.2 17.6 24.8 24.4 14.6 10.6 15.2 18.0 22.7 16.0 13.0 38.9 17.4 5.7 0.0 7.9 15.7 1.7 5.5 5.2 4.3 2.8 8.5 12.3 7.5 8.1 17.2 5.5 7.3 10.4 6.1 0.3 3.1 9.8 15.1 0.9 15.3 22.7 10.4 31.8 3.6 7.3 22.1 1.5 17.5 9.7 26.0 7.6 23.8 14.6 17.9 3.2 307.9 8.9 6.3 14.2 58.4 3.1 2.2 5.9 6.4 76.5 37.5 0.9 23.1 2.1 14.6 4.9 17.4 4.8 7.9 0.4 12.5 3.5 13.5 8.2 7.0 6.6 19.3 10.3 0.3 4.3 5.8 4.5 1.9 2.7 7.6 7.0 5.9 TBC1D20 "C20orf140, dJ852M4.2" ENSG00000125875 "TBC1 domain family member 20" Q96BZ9 20 423596-462566 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043613 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" "HPA043613: AB_10963930" "unprognostic (2.16e-3)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.14e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (3.68e-3)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (2.54e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "unprognostic (2.97e-1)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" 16.8 21.5 21.7 7.6 24.2 7.0 16.0 22.6 22.4 18.4 17.0 19.1 8.6 17.4 15.6 18.9 16.1 11.8 16.6 20.4 21.6 14.4 13.4 18.1 10.6 23.1 23.6 17.3 14.7 21.2 17.8 17.5 22.2 17.7 11.8 7.7 16.9 18.8 20.4 20.0 14.5 20.4 22.3 16.1 15.4 9.9 23.0 14.6 15.0 23.6 12.9 19.6 16.8 23.4 18.5 12.6 18.2 15.9 75.9 39.3 16.3 19.8 39.1 27.7 29.4 11.8 9.6 8.4 4.6 43.7 35.2 18.1 18.8 20.2 26.8 4.9 4.9 13.4 4.0 27.3 45.7 13.1 7.1 35.2 38.3 15.4 14.4 29.9 17.7 14.4 14.8 17.7 30.7 4.5 12.1 15.5 10.6 23.7 11.0 12.0 17.2 10.4 18.7 12.0 15.8 12.8 22.2 39.9 53.5 20.0 14.1 27.9 19.9 25.0 8.9 22.2 14.3 9.7 19.0 7.7 13.4 14.0 15.9 3.0 0.6 0.7 1.8 0.5 1.2 0.8 1.2 2.1 0.6 0.7 1.1 1.8 1.5 0.9 0.4 0.6 0.8 0.7 21.7 24.2 22.6 22.4 20.4 21.6 23.1 23.6 22.2 22.3 23.0 23.4 23.0 12.8 13.6 16.3 22.6 18.5 13.6 11.3 23.3 29.3 22.4 14.4 16.8 24.3 11.1 14.7 12.5 16.5 28.9 29.6 11.7 23.8 48.9 21.3 26.9 20.7 16.1 48.6 16.2 30.3 25.1 23.0 17.9 16.2 11.4 14.4 25.4 19.7 19.7 26.9 19.2 17.9 8.2 17.6 16.4 147.2 29.5 18.6 14.2 14.0 13.2 21.4 43.3 11.6 15.2 22.5 20.7 35.3 30.0 21.2 19.4 17.0 17.1 19.4 19.7 22.1 18.3 33.1 34.7 15.3 18.9 50.9 24.0 19.6 15.7 27.9 TCEAL7 "MGC23947, WEX5" ENSG00000182916 "Transcription elongation factor A like 7" Q9BRU2 X 103330229-103332326 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 55.2;Horizontal cells: 48.8;Leydig cells: 43.8;Muller glia cells: 88.3;Oligodendrocytes: 46.5;Peritubular cells: 39.1;Skeletal myocytes: 48.3;Smooth muscle cells: 38.7" "Cancer enriched" "Detected in many" 10 "glioma: 39.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 83.8;BJ hTERT+ SV40 Large T+ RasG12V: 75.1;GAMG: 115.3;hTEC/SVTERT24-B: 83.8;LHCN-M2: 72.0;SCLC-21H: 210.1;U-87 MG: 78.9" "Low region specificity" "Detected in many" "HPA051507, HPA065080" Enhanced Supported Nucleoplasm NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA051507: AB_2681512, HPA065080: AB_2685419" "unprognostic (1.09e-2)" "unprognostic (4.36e-2)" "unprognostic (5.54e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (4.52e-2)" "unprognostic (2.17e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (1.12e-1)" "unprognostic (4.18e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.62e-1)" "unprognostic (2.28e-2)" "unprognostic (1.35e-3)" 7.7 27.9 72.4 4.3 73.0 0.0 9.1 75.1 126.3 26.3 40.5 18.6 4.0 48.2 18.3 5.5 17.0 11.9 14.0 72.1 84.5 5.0 2.4 6.1 2.3 80.8 77.5 29.0 1.2 1.1 37.4 2.1 82.3 12.3 7.8 23.5 3.5 13.2 3.7 1.8 8.3 29.9 74.5 5.8 6.5 3.1 77.2 5.1 3.8 9.9 1.4 9.7 15.6 96.0 0.0 0.0 83.8 0.0 36.3 55.5 15.0 12.0 61.9 26.4 75.1 0.0 0.0 0.0 0.0 12.9 115.3 0.0 0.0 1.8 45.5 0.0 0.8 0.3 0.0 0.0 18.2 0.0 0.1 46.6 0.0 83.8 0.1 0.0 27.6 0.0 0.5 0.2 72.0 0.0 0.1 0.3 0.3 0.1 0.0 0.0 53.1 0.3 0.0 0.0 210.1 56.6 0.0 0.4 0.0 0.4 0.0 0.0 0.0 38.8 1.4 0.6 0.0 0.0 0.0 0.0 78.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 72.4 73.0 75.1 126.3 72.1 84.5 80.8 77.5 82.3 74.5 77.2 96.0 4.8 0.0 1.3 5.9 0.0 2.5 5.3 0.3 1.2 36.4 0.9 19.2 13.6 0.0 0.7 3.7 4.2 1.4 0.1 0.0 5.9 0.2 0.2 1.0 42.9 5.2 0.0 0.0 21.2 0.0 0.7 55.2 0.0 0.7 0.0 19.2 1.8 0.0 0.7 48.8 26.5 0.0 0.0 0.0 4.0 1.8 43.8 0.6 8.8 4.7 0.0 88.3 0.0 19.6 46.5 0.3 0.0 39.1 0.1 1.1 0.0 2.1 0.0 12.9 13.1 48.3 38.7 3.0 1.5 0.8 3.1 0.3 0.5 5.1 0.0 0.8 TENM4 "KIAA1302, ODZ4, Ten-M4, TEN4" ENSG00000149256 "Teneurin transmembrane protein 4" Q6N022 11 78652829-79441030 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;ovary: 16.6;parathyroid gland: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Early spermatids: 96.8;Excitatory neurons: 337.4;Inhibitory neurons: 297.7;Microglial cells: 117.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 9.1;hTERT-RPE1: 9.5;PC-3: 10.8;REH: 10.4;SH-SY5Y: 17.4" "Low region specificity" "Detected in all" "HPA019521, HPA065961" Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA019521: AB_2670171, HPA065961: AB_2685588" "unprognostic (2.81e-1)" "unprognostic (9.25e-2)" "unprognostic (1.64e-1)" "unprognostic (2.96e-3)" "unprognostic (1.87e-1)" "unprognostic (2.48e-1)" "unprognostic (1.18e-2)" "unprognostic (1.24e-1)" "unprognostic (3.01e-1)" "unprognostic (3.79e-1)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "unprognostic (6.51e-3)" "unprognostic (5.40e-3)" "unprognostic (5.64e-2)" "unprognostic (7.07e-2)" "unprognostic (9.81e-3)" 1.9 1.4 7.5 1.0 13.4 0.0 0.7 0.3 12.6 2.5 0.0 0.5 0.1 1.3 0.2 2.0 2.1 0.4 0.4 9.0 7.5 1.5 0.0 0.4 0.5 10.9 9.2 16.6 0.3 14.0 7.1 0.1 7.9 0.4 0.3 2.6 0.5 0.2 0.4 3.3 0.3 1.0 13.0 0.3 0.5 1.6 11.8 1.9 5.8 1.0 1.2 0.5 1.5 17.8 0.0 0.0 3.4 0.0 3.7 5.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 7.8 6.7 0.0 2.1 5.0 5.3 0.0 4.5 0.9 0.0 0.0 0.0 0.1 0.0 0.0 9.1 2.3 2.5 4.5 9.5 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.0 1.8 0.3 10.8 10.4 0.0 0.0 6.4 1.1 7.1 17.4 0.0 0.0 0.0 6.2 0.0 0.1 0.5 0.1 1.2 0.1 5.9 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 13.4 0.3 12.6 9.0 7.5 10.9 9.2 7.9 13.0 11.8 17.8 0.1 0.0 0.0 134.5 0.2 0.9 0.8 3.4 17.1 7.5 0.1 0.0 1.9 4.3 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 96.8 1.1 1.7 0.3 0.0 0.0 337.4 0.0 0.2 2.6 0.0 0.8 1.3 0.8 0.0 0.0 0.1 0.0 297.7 0.0 0.0 0.6 0.4 56.6 5.3 0.7 0.0 117.1 0.4 13.9 0.0 58.3 21.3 0.0 0.0 1.9 0.0 0.4 0.0 0.4 7.0 1.0 0.0 25.1 2.8 4.8 1.0 7.3 2.0 0.1 0.1 0.3 0.0 0.6 TFE3 "bHLHe33, TFEA" ENSG00000068323 "Transcription factor binding to IGHM enhancer 3" P19532 X 49028726-49043410 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.5" "Group enriched" "Detected in many" 4 "granulocytes: 12.5;monocytes: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023881 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA023881: AB_1857931" "unprognostic (2.68e-2)" "unprognostic (2.89e-3)" "unprognostic (2.40e-2)" "unprognostic (5.36e-2)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (6.03e-5)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "unprognostic (4.32e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.19e-8)" "unprognostic (1.93e-1)" "unprognostic (8.77e-2)" "unprognostic (4.19e-2)" "unprognostic (6.25e-1)" 31.3 23.6 27.8 16.8 27.3 24.1 22.9 25.8 26.9 24.1 23.3 23.6 10.8 24.7 21.1 15.6 26.2 18.5 17.2 25.7 29.4 15.1 12.6 29.2 11.8 37.2 30.9 25.8 12.4 25.1 18.4 20.8 28.7 17.2 11.5 14.8 13.4 28.3 17.0 20.5 14.7 24.7 27.5 22.5 16.8 5.9 32.2 10.7 20.0 14.0 13.2 25.0 20.5 25.6 32.8 41.5 14.6 44.6 48.6 45.1 12.5 40.6 55.8 49.7 38.2 23.3 26.8 10.2 18.0 65.7 48.6 25.5 25.4 40.2 44.8 24.4 11.8 8.3 39.6 26.2 69.0 10.0 28.3 38.5 32.3 64.4 50.1 47.8 26.3 8.4 19.8 55.9 49.2 20.6 7.5 17.2 36.3 11.0 34.1 11.9 22.2 26.6 43.1 18.0 12.4 12.4 44.8 19.0 17.9 52.5 27.6 15.0 48.5 47.1 48.7 48.0 27.3 30.1 29.7 8.0 56.1 14.0 33.2 0.0 4.8 1.8 0.6 4.7 1.1 0.5 0.9 0.5 2.2 1.0 0.6 0.5 12.5 0.4 6.3 0.5 1.3 2.6 27.8 27.3 25.8 26.9 25.7 29.4 37.2 30.9 28.7 27.5 32.2 25.6 13.8 16.0 8.8 13.7 9.8 19.8 19.7 11.2 30.1 6.8 10.9 9.4 8.1 15.7 11.8 20.2 4.2 16.0 4.4 14.3 9.8 17.7 0.7 10.9 15.3 17.5 12.5 5.2 7.5 15.8 9.4 20.2 14.3 14.8 5.7 12.0 10.8 15.0 22.3 18.5 7.2 8.2 0.0 21.7 29.4 2.2 27.4 20.5 8.8 11.2 15.5 12.0 4.1 6.0 7.7 21.4 13.7 24.5 12.9 20.2 10.6 12.1 7.0 5.6 13.1 18.5 14.3 2.2 0.8 18.9 22.0 37.1 8.6 13.9 7.5 19.6 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 THRA "AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3" ENSG00000126351 "Thyroid hormone receptor alpha" P10827 17 40058290-40093867 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 236.7" "Cell type enhanced" "Detected in many" "Muller glia cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009654, CAB023349" Approved Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB023349: AB_619577, HPA009654: AB_1854603" "unprognostic (2.75e-2)" "unprognostic (2.20e-1)" "unprognostic (6.64e-2)" "unprognostic (4.22e-2)" "unprognostic (8.78e-2)" "unprognostic (1.64e-1)" "unprognostic (3.41e-3)" "prognostic favorable (1.84e-4)" "unprognostic (1.47e-1)" "unprognostic (5.47e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-2)" "prognostic favorable (6.05e-8)" "unprognostic (3.05e-1)" "unprognostic (1.35e-1)" "unprognostic (4.21e-1)" "unprognostic (1.88e-3)" 40.7 43.7 199.1 12.0 236.7 23.0 38.9 159.3 218.3 67.5 108.5 67.2 31.1 49.9 22.0 19.1 57.7 25.8 63.8 189.7 181.8 34.1 10.2 32.2 9.7 162.4 172.1 90.7 31.3 29.9 50.0 17.1 149.4 34.5 18.8 35.4 27.3 35.5 90.7 50.2 36.2 34.6 166.5 13.9 48.0 18.7 183.6 12.8 32.6 52.8 6.3 45.0 45.9 179.9 4.9 37.6 11.5 28.9 77.4 28.2 4.2 19.3 23.0 19.6 18.2 31.5 27.2 5.6 31.3 37.6 8.7 11.4 22.6 11.7 10.6 2.1 21.6 10.4 44.5 13.4 26.0 16.9 11.2 45.1 9.5 18.4 7.1 45.4 26.6 16.7 21.2 5.2 16.5 7.1 22.8 27.4 10.6 24.6 11.8 32.1 22.7 27.6 6.4 3.3 19.5 17.7 14.8 23.3 33.7 17.5 27.3 19.5 18.7 19.4 18.9 17.7 5.9 11.9 9.0 3.4 12.0 19.1 10.6 0.2 0.3 1.9 2.0 0.1 0.8 0.2 0.8 1.2 0.3 0.4 1.4 1.7 1.1 2.1 0.3 0.6 1.0 0.7 199.1 236.7 159.3 218.3 189.7 181.8 162.4 172.1 149.4 166.5 183.6 179.9 32.2 19.2 7.3 27.1 6.2 10.6 28.1 3.3 31.3 76.4 19.6 21.2 45.4 38.6 2.7 33.1 20.9 0.8 16.5 37.9 50.9 12.3 1.1 20.5 29.5 20.8 25.1 17.9 19.1 14.8 1.4 36.8 29.0 12.1 14.0 23.1 24.7 13.8 11.6 62.2 24.2 22.6 6.1 10.6 5.1 2.7 51.6 8.6 19.6 8.4 5.1 95.2 37.0 15.6 26.5 6.9 14.6 49.7 3.9 17.2 58.8 29.9 7.5 22.5 19.7 84.7 44.4 0.3 27.3 14.6 10.4 0.3 18.1 16.3 39.9 13.8 TJP1 "DKFZp686M05161, MGC133289, ZO-1" ENSG00000104067 "Tight junction protein 1" Q07157 15 29699367-29968915 "Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 893.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001636, HPA001637, CAB010822" Enhanced Enhanced "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "CAB010822: , HPA001636: AB_1080762, HPA001637: AB_1080760" "unprognostic (2.11e-2)" "unprognostic (6.83e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-2)" "unprognostic (9.43e-2)" "unprognostic (1.21e-1)" "unprognostic (4.54e-2)" "unprognostic (6.71e-3)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.86e-3)" "unprognostic (3.54e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.85e-3)" "unprognostic (3.02e-1)" "unprognostic (5.04e-2)" "unprognostic (1.20e-1)" 37.4 16.5 22.1 4.4 35.3 1.1 30.8 21.4 24.4 33.2 17.9 30.5 7.1 42.3 16.5 60.4 27.8 12.6 37.1 22.0 22.2 24.3 18.6 34.0 5.7 26.6 28.6 22.3 30.0 13.4 16.8 31.6 25.2 20.4 9.5 10.0 29.6 10.9 22.0 27.8 19.8 17.4 20.6 13.5 25.8 29.7 30.3 3.7 24.8 5.0 10.2 23.8 35.3 42.6 62.4 36.8 29.1 18.4 17.0 31.7 28.9 18.6 21.1 18.0 20.2 59.2 22.9 0.3 24.8 24.6 21.3 47.4 20.1 23.8 19.0 0.5 14.9 0.3 22.3 24.7 57.9 0.1 0.8 16.5 15.8 21.4 39.2 23.0 38.2 0.1 24.3 12.5 14.2 32.2 0.2 0.7 21.9 23.4 14.6 0.1 35.0 0.2 28.1 33.4 12.9 16.8 39.2 12.8 16.8 42.9 13.3 0.6 54.7 14.3 23.9 12.5 25.6 4.4 4.6 0.4 17.8 0.3 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 35.3 21.4 24.4 22.0 22.2 26.6 28.6 25.2 20.6 30.3 42.6 212.1 169.9 49.2 299.7 1.6 35.8 115.2 36.4 39.3 42.4 53.7 28.6 107.2 51.5 48.6 58.8 10.4 32.3 0.8 87.7 25.4 116.0 19.1 132.2 97.0 166.0 46.0 2.7 293.8 83.7 11.3 56.6 86.6 290.7 5.7 87.7 100.3 49.1 3.8 126.2 187.3 45.4 32.6 6.1 12.1 13.7 33.8 5.2 64.0 266.1 1.6 32.8 0.0 345.3 893.8 178.3 82.0 63.9 5.9 151.4 37.8 26.0 39.2 52.4 78.9 64.1 118.7 63.0 83.9 139.2 60.1 33.7 4.1 120.8 33.1 194.6 TM4SF18 L6D ENSG00000163762 "Transmembrane 4 L six family member 18" Q96CE8 3 149318498-149334414 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.9" "Group enriched" "Detected in many" 4 "Adipocytes: 226.1;Endothelial cells: 188.9;Hepatic stellate cells: 151.0" "Cancer enhanced" "Detected in all" "renal cancer: 17.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 94.8;EFO-21: 194.9;GAMG: 38.7;HUVEC TERT2: 65.9;NTERA-2: 47.2" "Low region specificity" "Detected in many" "HPA053639, HPA069378" Approved Supported Vesicles,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "HPA053639: , HPA069378: AB_2686133" "unprognostic (2.25e-1)" "unprognostic (3.68e-1)" "unprognostic (4.76e-2)" "unprognostic (1.08e-1)" "unprognostic (9.11e-3)" "unprognostic (1.05e-2)" "prognostic favorable (8.63e-4)" "unprognostic (2.84e-1)" "unprognostic (6.13e-3)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (1.75e-1)" "unprognostic (5.71e-2)" "unprognostic (3.56e-3)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (1.97e-1)" 21.3 5.2 9.4 4.9 9.6 0.1 16.3 9.2 11.5 8.3 10.4 3.4 3.9 7.6 4.7 3.4 6.4 10.6 8.4 9.1 10.3 19.1 7.9 9.2 6.6 12.2 9.6 3.2 9.8 6.8 3.1 17.4 11.5 4.0 3.3 1.1 4.0 6.5 5.9 2.4 3.6 14.9 10.0 33.9 3.4 1.9 12.1 2.1 12.7 5.7 5.0 6.7 2.5 10.4 0.1 94.8 3.5 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.2 1.2 0.0 194.9 0.0 38.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.3 0.1 0.7 0.0 0.0 0.0 24.7 65.9 0.0 0.0 0.0 6.2 0.7 0.0 0.2 47.2 0.0 0.0 0.1 2.6 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.5 1.5 0.1 0.1 8.4 0.1 1.2 0.0 0.5 0.1 0.1 0.5 0.0 0.1 15.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 9.4 9.6 9.2 11.5 9.1 10.3 12.2 9.6 11.5 10.0 12.1 10.4 226.1 0.0 4.4 0.3 1.6 3.2 0.2 0.0 0.6 0.2 41.4 23.9 2.8 4.3 0.0 1.8 0.0 0.0 1.0 0.0 9.8 35.2 0.4 0.7 1.1 188.9 0.0 0.0 0.0 0.2 0.0 6.2 0.0 0.9 1.3 0.3 151.0 1.1 0.1 0.0 0.1 0.0 0.0 9.1 3.0 1.8 2.1 1.2 1.8 33.7 0.6 0.4 0.0 0.5 0.6 0.9 0.0 6.8 2.5 1.3 0.0 35.8 0.7 0.0 0.0 1.5 2.5 0.2 0.5 0.2 2.8 0.0 1.1 5.2 0.0 0.6 TMEM132C "DKFZp761O2018, PPP1R152" ENSG00000181234 "Transmembrane protein 132C" Q8N3T6 12 128267403-128707915 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.6" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 217.3;Microglial cells: 160.2;Oligodendrocyte precursor cells: 580.6" "Group enriched" "Detected in some" 4 "glioma: 1.6;ovarian cancer: 4.6;testis cancer: 4.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "gdT-cell: 1.9" "Lineage enriched" "Detected in single" 19 "T-cells: 1.9" "Group enriched" "Detected in some" 7 "AF22: 3.7;ASC diff: 5.2;Daudi: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015633, HPA015984" Approved Centrosome,Cytosol NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Centrosome, Cytosol" "HPA015633: AB_1858089, HPA015984: AB_1858088" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (7.34e-2)" "unprognostic (8.60e-2)" "unprognostic (2.37e-1)" "unprognostic (1.99e-3)" "unprognostic (5.48e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.85e-2)" "unprognostic (6.29e-2)" "unprognostic (7.97e-3)" "unprognostic (2.54e-1)" "unprognostic (5.71e-2)" "unprognostic (6.33e-3)" 31.6 2.7 8.3 0.3 7.6 0.0 14.0 6.8 7.3 16.8 15.5 1.4 0.3 5.4 3.8 3.1 11.8 1.1 4.3 6.7 7.4 0.4 0.1 1.5 1.1 9.3 14.4 8.6 2.7 0.1 0.7 2.5 8.7 2.4 0.4 3.6 1.7 4.1 0.5 2.0 1.8 1.0 6.7 0.3 1.2 1.3 9.6 1.0 0.9 3.4 0.4 4.7 9.2 6.0 0.0 0.0 3.7 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.6 6.8 7.3 6.7 7.4 9.3 14.4 8.7 6.7 9.6 6.0 1.9 0.0 0.0 70.2 0.0 0.4 0.0 0.0 0.0 18.6 0.0 0.0 1.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 1.1 0.2 7.6 26.1 1.0 0.0 0.0 32.2 0.0 0.0 6.3 0.0 9.8 0.0 3.7 0.0 0.0 0.1 0.0 217.3 0.1 0.0 0.0 1.1 0.2 9.0 0.1 1.8 160.2 0.0 0.4 0.0 580.6 42.3 0.1 0.0 15.1 0.0 0.0 0.1 0.1 0.0 2.3 0.0 0.8 2.5 0.1 0.4 0.1 0.0 0.0 0.3 0.0 0.1 0.0 TMEM158 "p40BBp, RIS1" ENSG00000249992 "Transmembrane protein 158" Q8WZ71 3 45224466-45226287 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;endometrium 1: 69.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 24.5;Breast myoepithelial cells: 24.5;Endometrial stromal cells: 61.0;Muller glia cells: 87.4" "Cancer enhanced" "Detected in many" "glioma: 38.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 336.1;GAMG: 111.9;U-138 MG: 138.9;U-87 MG: 455.3" "Region enhanced" "Detected in all" "basal ganglia: 95.5" "Low region specificity" "Detected in all" HPA074974 Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" "HPA074974: AB_2732274" "unprognostic (3.84e-1)" "unprognostic (9.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (3.77e-2)" "unprognostic (5.73e-2)" "unprognostic (3.31e-2)" "unprognostic (4.67e-3)" "unprognostic (6.23e-2)" "unprognostic (6.41e-2)" "unprognostic (1.84e-3)" "prognostic favorable (6.43e-5)" "prognostic unfavorable (5.42e-9)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (2.86e-2)" "unprognostic (4.49e-3)" 2.6 9.2 20.3 3.8 33.3 1.9 1.6 7.5 23.0 8.6 8.5 8.1 0.7 69.5 2.2 18.2 3.9 6.4 0.7 22.4 23.9 3.6 0.7 1.6 0.5 10.6 22.5 1.4 1.9 0.2 12.2 0.8 10.4 13.2 1.9 1.5 1.4 22.7 2.0 2.4 1.9 17.0 15.2 0.4 1.9 2.5 27.4 0.2 0.7 0.7 1.1 8.7 2.8 13.8 12.9 2.1 4.4 0.8 7.7 18.3 3.7 31.6 336.1 17.0 27.5 0.7 0.8 0.1 1.6 10.5 111.9 17.2 5.1 1.4 50.2 0.8 2.0 0.0 6.1 0.1 10.7 2.5 6.1 24.6 0.6 33.7 2.7 39.2 1.8 0.0 80.3 0.9 30.4 0.5 0.0 22.3 37.8 0.3 46.5 0.0 1.0 4.9 6.7 11.9 6.1 1.4 12.2 0.4 2.1 3.4 0.3 4.3 5.1 138.9 10.4 88.4 110.2 0.0 0.1 0.0 455.3 12.6 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.3 33.3 7.5 23.0 22.4 23.9 10.6 22.5 10.4 15.2 27.4 13.8 1.6 0.0 0.5 1.6 0.4 24.5 6.1 2.1 2.8 4.4 13.1 24.5 1.0 1.5 0.8 9.2 0.0 0.1 0.5 0.6 0.0 2.9 0.2 10.8 61.0 1.3 7.7 0.0 8.7 0.4 0.1 9.3 0.5 4.2 0.0 0.7 2.5 2.7 5.1 1.7 5.7 0.6 2.0 0.8 16.4 0.7 8.4 6.4 0.0 1.9 1.4 87.4 0.0 6.0 1.2 1.0 0.5 0.0 0.0 1.7 0.0 0.2 0.4 2.9 0.0 4.9 8.3 0.3 0.5 1.0 10.5 0.3 0.6 16.7 0.7 4.2 TMEM165 "GDT1, TMPT27, TPARL" ENSG00000134851 "Transmembrane protein 165" Q9HC07 4 55395957-55453397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 1021.6;Urothelial cells: 601.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038299, HPA062424" Supported Enhanced "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA038299: AB_10675793, HPA062424: AB_2732682" "unprognostic (2.53e-2)" "unprognostic (1.08e-3)" "unprognostic (3.46e-3)" "unprognostic (7.07e-3)" "unprognostic (5.97e-2)" "unprognostic (9.84e-2)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.41e-1)" "unprognostic (1.18e-2)" "unprognostic (8.00e-3)" "unprognostic (1.55e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.18e-8)" "unprognostic (9.05e-2)" "unprognostic (8.96e-2)" "unprognostic (2.72e-1)" "unprognostic (2.18e-2)" 53.4 61.3 39.2 42.6 75.1 11.3 35.2 62.0 70.8 45.9 36.0 32.4 32.0 34.0 31.1 55.8 31.6 46.0 37.3 40.8 51.1 41.6 19.3 52.7 32.6 84.8 72.0 22.3 40.1 32.3 24.0 60.5 78.9 37.8 33.3 15.0 40.4 30.6 17.1 26.2 27.9 40.0 54.5 37.0 39.2 13.7 65.8 24.0 37.8 17.2 42.5 78.8 42.7 117.4 74.6 30.4 47.1 50.2 143.5 105.4 50.0 138.6 212.7 98.0 106.7 34.2 108.3 76.9 98.3 85.9 56.2 53.8 50.0 56.8 98.9 43.8 46.4 66.0 50.1 66.6 89.1 92.1 75.1 109.1 72.7 55.9 37.3 82.4 113.2 25.6 112.8 47.8 116.5 54.5 73.0 76.5 51.7 97.8 70.6 52.0 35.5 42.1 148.6 70.2 48.3 64.7 69.8 261.0 85.8 46.3 41.2 65.3 98.3 83.1 49.6 37.0 102.5 44.4 38.5 48.3 98.9 77.2 67.9 23.7 40.4 26.0 15.2 35.7 17.0 19.0 14.3 17.8 36.5 11.5 12.1 14.4 28.6 18.1 35.9 28.4 18.3 30.2 39.2 75.1 62.0 70.8 40.8 51.1 84.8 72.0 78.9 54.5 65.8 117.4 119.6 54.5 52.4 42.7 87.9 245.1 277.8 295.0 147.4 50.6 85.8 42.7 32.2 71.4 214.9 79.1 81.3 112.5 97.7 42.4 17.6 171.1 32.1 123.6 99.1 108.0 50.4 79.1 58.2 163.5 157.2 110.4 76.0 173.8 21.0 57.6 113.8 18.4 105.7 28.6 71.5 69.4 77.3 97.9 145.7 24.7 58.7 109.5 88.9 59.0 117.5 53.2 123.6 71.4 1021.6 248.0 48.6 63.6 117.1 239.3 51.3 50.0 125.2 91.9 98.6 92.2 129.0 37.8 24.6 169.4 268.8 80.6 81.6 90.6 61.6 601.6 TMEM184B "C22orf5, DKFZP586A1024, FM08, HS5O6A" ENSG00000198792 "Transmembrane protein 184B" Q9Y519 22 38219291-38273010 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 86.8;Oligodendrocytes: 93.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 197.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024076 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus, Cytosol" Nucleoplasm "HPA024076: AB_1858106" "unprognostic (1.52e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-1)" "unprognostic (8.96e-2)" "unprognostic (3.82e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (5.94e-6)" "unprognostic (1.14e-2)" "unprognostic (5.18e-2)" "unprognostic (4.52e-2)" "unprognostic (9.20e-2)" "unprognostic (1.77e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (2.96e-1)" 28.6 21.9 49.5 14.0 52.3 5.8 24.9 54.5 59.6 18.6 22.1 21.0 16.9 19.4 7.2 17.3 17.1 14.5 35.7 49.6 48.2 25.9 11.4 35.9 8.4 56.8 56.0 16.2 18.4 18.9 34.3 38.4 54.8 18.8 10.8 15.2 22.6 14.4 28.7 16.0 17.6 14.0 52.9 22.0 22.4 7.5 56.7 6.2 26.1 17.4 8.2 18.4 16.5 66.9 55.8 47.5 27.5 21.9 53.6 42.6 63.4 58.8 82.9 46.9 41.5 35.1 25.2 10.6 44.9 87.6 42.4 67.2 24.9 57.8 31.6 37.9 45.0 20.9 34.0 29.5 56.3 16.6 28.0 36.1 50.2 55.4 61.5 48.5 59.5 15.9 13.5 36.2 41.5 31.6 10.6 14.1 22.4 41.2 43.4 18.1 24.8 10.6 34.8 60.6 59.3 10.5 44.2 63.6 32.0 31.7 35.2 12.0 89.2 47.7 48.4 42.5 36.2 74.5 197.9 8.5 69.2 12.1 42.0 14.2 3.3 4.7 5.3 2.3 4.6 1.4 2.9 4.0 4.5 1.1 2.1 2.5 10.9 6.2 1.6 7.0 1.0 3.2 49.5 52.3 54.5 59.6 49.6 48.2 56.8 56.0 54.8 52.9 56.7 66.9 43.4 6.4 14.8 86.8 7.5 12.4 19.8 22.3 17.6 16.4 15.9 10.5 17.1 8.6 18.7 14.7 2.1 35.0 17.8 12.5 3.9 17.3 5.6 17.4 15.5 34.6 25.9 4.6 42.6 22.2 48.3 17.4 13.3 33.8 2.5 15.3 18.2 4.4 14.7 15.2 40.7 19.7 12.2 8.5 19.7 2.4 11.8 8.4 14.2 22.5 12.2 44.4 23.7 42.3 93.1 28.3 9.8 13.5 35.6 32.9 11.1 4.3 15.9 9.0 19.7 15.3 27.0 3.3 6.1 5.3 9.7 78.4 9.3 10.2 10.1 37.0 TMEM273 "C10orf128, Em:AC084727.5" ENSG00000204161 "Transmembrane protein 273" Q5T292 10 49154725-49188585 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 37.8;dendritic cells: 10.1;Hofbauer cells: 82.9;Macrophages: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 269.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 269.0" "Cell line enhanced" "Detected in some" "HDLM-2: 214.8;HEL: 51.7;K-562: 101.4;U-266/84: 38.3;U-87 MG: 102.2;U-937: 91.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058166 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA058166: AB_2683627" "unprognostic (1.33e-1)" "unprognostic (5.67e-4)" "unprognostic (1.34e-2)" "unprognostic (1.21e-1)" "unprognostic (4.50e-2)" "unprognostic (4.13e-2)" "unprognostic (5.86e-3)" "unprognostic (9.13e-3)" "unprognostic (2.61e-1)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (2.86e-5)" "unprognostic (2.45e-2)" "unprognostic (2.22e-2)" "unprognostic (8.69e-3)" "unprognostic (1.24e-1)" 31.5 3.0 15.1 17.2 22.1 4.0 27.5 23.0 27.1 15.1 13.4 12.8 8.8 13.7 6.1 8.4 12.8 18.3 28.0 15.2 18.2 6.0 9.5 27.1 22.2 25.0 22.8 3.9 4.0 14.4 3.3 10.9 25.0 8.2 14.2 1.1 9.8 7.8 8.5 7.3 24.3 20.9 18.9 29.8 8.9 1.9 20.5 7.8 10.2 16.5 23.4 14.4 12.7 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 214.8 0.0 51.7 0.0 0.0 0.0 0.5 21.9 0.0 0.0 0.0 0.0 0.0 1.4 0.2 101.4 6.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.3 0.0 0.0 0.0 0.1 0.0 38.3 0.1 102.2 91.6 0.0 24.9 4.2 269.0 22.9 1.4 36.5 35.9 13.8 22.0 19.8 18.5 0.7 6.1 19.4 0.2 0.7 0.6 11.2 11.5 15.1 22.1 23.0 27.1 15.2 18.2 25.0 22.8 25.0 18.9 20.5 30.7 37.8 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 1.8 0.0 0.8 10.1 0.0 0.0 0.1 0.0 1.1 0.2 9.4 0.0 0.0 0.0 0.0 0.7 0.5 0.0 2.0 0.0 0.0 0.0 0.0 82.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.1 5.6 0.0 0.0 0.0 TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;intestine: 36.8;seminal vesicle: 50.9" "Cell type enriched" "Detected in some" 5 "Theca cells: 37.5" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;HUVEC TERT2: 52.5;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" 3.5 6.9 20.8 1.3 20.4 0.0 0.8 18.5 28.5 4.6 2.5 36.8 3.4 7.8 3.6 11.2 4.1 3.4 0.5 28.4 71.9 0.5 0.0 2.3 0.1 21.8 21.3 7.9 0.2 12.7 2.2 0.1 36.8 22.3 9.6 10.2 0.5 50.9 0.8 0.6 7.2 10.3 15.6 0.8 5.2 1.4 47.5 0.2 0.8 2.5 0.3 9.7 4.4 13.5 0.0 0.0 5.4 0.0 3.9 10.1 0.0 1.1 0.7 0.4 0.2 0.0 0.0 0.0 0.1 3.2 0.0 0.0 3.4 0.0 1.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 0.0 3.5 0.0 1.9 0.0 7.5 52.5 0.0 0.0 0.1 6.6 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 13.2 0.0 0.0 0.0 1.3 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 20.4 18.5 28.5 28.4 71.9 21.8 21.3 36.8 15.6 47.5 13.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 7.4 0.4 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.2 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 37.5 0.0 0.0 TMEM47 "BCMP1, DKFZp564E153, DKFZP761J17121, TM4SF10, VAB-9" ENSG00000147027 "Transmembrane protein 47" Q9BQJ4 X 34627075-34657285 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 110.7;Astrocytes: 85.5;Leydig cells: 74.3;Muller glia cells: 148.0;Peritubular cells: 92.9;Sertoli cells: 92.1;Skeletal myocytes: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 112.6;fHDF/TERT166: 348.1;RPTEC TERT1: 83.6;U-2197: 74.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046658 Approved Approved "Nuclear membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane" "HPA046658: AB_2679742" "unprognostic (1.50e-1)" "unprognostic (1.44e-1)" "unprognostic (5.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "unprognostic (3.82e-2)" "unprognostic (6.74e-3)" "unprognostic (7.29e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.67e-2)" "unprognostic (4.23e-2)" "unprognostic (1.36e-1)" "prognostic favorable (4.05e-6)" "unprognostic (2.69e-2)" "unprognostic (7.19e-2)" "unprognostic (2.76e-1)" "unprognostic (9.94e-2)" 40.0 20.8 34.8 8.5 38.3 0.0 18.8 27.1 39.5 46.7 41.6 25.9 8.6 45.7 33.4 34.6 35.1 28.6 36.1 30.8 35.8 27.7 24.8 21.9 6.2 36.5 38.7 21.7 11.3 5.6 6.6 1.2 33.7 32.9 14.9 17.8 29.6 45.6 23.8 6.3 11.5 51.0 37.8 7.5 13.8 4.9 39.5 3.1 20.2 31.1 4.2 36.2 20.1 33.4 0.0 1.7 50.7 21.4 43.8 33.1 0.0 112.6 0.3 21.8 18.7 0.1 0.0 0.0 9.2 348.1 0.0 0.1 14.5 4.0 32.0 0.0 9.9 0.0 13.2 0.0 25.3 0.0 0.0 30.0 0.1 8.9 9.7 38.9 24.8 0.0 0.0 0.0 41.6 0.9 0.0 0.0 6.0 0.6 0.3 0.0 25.3 0.0 83.6 33.0 0.5 0.0 0.1 1.3 0.0 5.4 0.2 0.0 0.9 44.0 4.4 74.4 4.8 0.0 0.0 0.0 18.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 38.3 27.1 39.5 30.8 35.8 36.5 38.7 33.7 37.8 39.5 33.4 110.7 19.2 0.6 85.5 0.1 8.2 15.9 0.9 1.8 8.3 10.8 12.7 27.7 10.0 1.5 16.5 6.2 0.0 0.6 0.0 7.9 0.8 0.4 7.6 4.6 29.8 0.0 0.0 4.3 5.3 0.2 48.3 1.1 6.2 2.5 0.7 46.4 17.5 0.1 30.3 25.6 0.0 0.0 0.8 11.7 3.8 74.3 1.2 65.8 13.1 0.0 148.0 0.0 5.0 2.2 3.0 0.0 92.9 0.1 14.3 0.0 13.4 2.0 7.3 92.1 84.7 67.1 0.3 2.1 1.9 5.3 0.1 0.7 0.8 0.0 12.1 TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: AB_2685429" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "prognostic favorable (8.64e-5)" "unprognostic (1.45e-1)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (7.39e-2)" "unprognostic (7.92e-3)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.44e-2)" "unprognostic (2.39e-3)" "unprognostic (6.66e-2)" "unprognostic (2.91e-1)" "unprognostic (3.91e-3)" "unprognostic (3.44e-2)" 47.2 63.0 43.9 44.5 47.8 41.8 55.5 45.3 55.8 47.0 43.7 58.5 49.6 35.7 53.0 36.5 38.4 45.7 44.2 45.0 44.4 55.0 33.4 58.1 52.2 46.5 44.4 26.2 32.6 49.5 14.6 57.7 46.4 54.4 65.7 45.4 81.5 52.7 16.9 41.1 55.4 46.0 47.2 46.9 49.5 16.1 45.5 47.1 47.0 26.5 47.3 55.1 29.8 50.4 43.3 44.6 74.3 42.3 132.9 119.8 28.1 89.0 123.6 143.4 159.5 36.5 110.9 50.2 47.9 274.6 55.7 62.6 56.3 61.9 161.2 126.1 81.4 104.7 47.5 55.2 96.5 82.4 80.3 128.0 91.4 106.1 60.5 69.7 107.0 50.8 73.1 79.5 140.9 30.6 53.2 90.2 90.6 73.7 37.1 45.7 85.3 88.9 148.8 30.9 64.5 42.3 89.0 64.2 72.2 69.3 32.7 52.0 171.0 86.5 36.6 144.9 36.8 52.3 61.5 45.0 117.1 117.2 50.3 275.5 76.9 109.8 87.9 94.7 91.9 49.6 77.2 91.1 55.9 40.9 55.1 76.6 159.2 80.5 117.3 51.9 95.4 106.3 43.9 47.8 45.3 55.8 45.0 44.4 46.5 44.4 46.4 47.2 45.5 50.4 244.8 144.2 84.2 21.2 107.9 253.4 184.5 392.3 146.8 43.9 162.0 164.8 105.6 102.9 212.7 169.2 27.1 108.9 191.0 175.6 50.9 300.3 25.4 136.4 119.3 203.3 83.0 93.6 31.6 215.6 312.5 198.1 91.3 180.8 126.6 58.2 152.0 68.3 227.1 25.2 27.3 170.7 309.3 162.4 245.1 12.7 151.9 223.8 199.3 16.9 253.8 102.0 154.5 28.1 48.8 315.3 164.8 98.9 168.2 340.6 120.0 113.1 205.1 41.7 210.4 71.6 200.6 94.7 47.0 166.8 317.7 181.6 180.9 116.9 106.9 274.3 TMEM74B "C20orf46, FLJ11190" ENSG00000125895 "Transmembrane protein 74B" Q9NUR3 20 1180561-1185415 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 15.6;Horizontal cells: 18.5;Inhibitory neurons: 16.3;Paneth cells: 15.6;Proximal enterocytes: 21.1;Sertoli cells: 19.7;Smooth muscle cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.3;Hep G2: 9.2;K-562: 16.8;Karpas-707: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045213 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Golgi apparatus" "HPA045213: AB_10961999" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (2.37e-1)" "unprognostic (2.05e-3)" "unprognostic (5.73e-2)" "unprognostic (1.03e-2)" "unprognostic (6.91e-3)" "unprognostic (1.97e-1)" "unprognostic (1.77e-4)" "unprognostic (9.58e-2)" "prognostic favorable (3.07e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.55e-7)" "unprognostic (1.20e-1)" "unprognostic (9.77e-2)" "unprognostic (8.37e-2)" "unprognostic (5.07e-3)" 5.8 2.0 17.5 1.0 16.2 0.2 4.9 10.3 19.4 1.9 8.8 4.0 18.2 2.0 0.8 4.0 7.4 3.9 11.2 13.5 16.6 4.5 4.7 27.6 2.0 19.8 13.2 1.0 2.0 7.1 10.1 17.2 18.2 3.1 1.8 3.9 6.3 15.7 5.1 9.8 23.1 2.0 10.8 2.8 4.1 4.1 17.8 0.3 4.1 2.2 1.2 1.2 2.0 11.5 0.0 4.4 2.5 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.3 0.6 0.1 0.9 0.0 2.7 0.3 3.4 0.4 0.1 0.0 4.2 1.1 0.0 9.2 0.0 0.0 1.2 0.0 0.9 0.0 0.1 0.1 0.1 0.6 16.8 7.1 0.0 0.0 0.1 0.0 3.0 1.2 0.3 0.0 0.2 0.0 0.7 0.6 0.5 1.9 0.1 0.0 0.1 0.9 0.0 0.0 1.7 0.0 2.9 0.0 0.1 2.7 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 16.2 10.3 19.4 13.5 16.6 19.8 13.2 18.2 10.8 17.8 11.5 3.7 0.0 0.0 0.7 0.1 0.3 0.7 0.9 0.6 10.5 2.2 1.0 2.3 0.0 0.2 0.0 0.0 0.2 0.2 1.0 0.0 0.5 1.0 0.2 0.1 3.3 15.6 0.0 9.7 0.2 1.8 0.8 2.6 0.1 0.0 0.5 4.6 0.8 0.0 18.5 16.3 9.9 2.0 0.6 0.7 0.7 0.0 1.4 1.8 1.9 1.0 0.5 0.0 0.0 1.1 0.9 15.6 0.0 0.1 0.7 21.1 0.6 1.2 4.0 19.7 0.4 13.3 0.2 2.7 0.2 0.9 1.4 0.2 0.3 3.9 0.3 TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 250.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 11 "dendritic cells: 4.1" "Cell line enhanced" "Detected in many" "CACO-2: 277.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA040473: AB_10794876, HPA053385: AB_2682134" "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.36e-3)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.14e-4)" "prognostic favorable (7.10e-4)" "unprognostic (6.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.41e-1)" "unprognostic (9.18e-3)" "prognostic favorable (3.85e-4)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" 56.3 50.6 48.9 17.3 84.1 4.7 44.5 75.3 64.1 68.6 161.9 90.0 102.5 100.4 74.2 27.9 96.5 93.9 44.3 51.2 56.9 36.5 27.5 58.1 5.7 72.8 77.4 191.9 88.5 53.7 23.9 28.2 69.7 80.7 96.3 15.7 50.1 23.9 5.3 24.6 118.4 62.3 51.9 19.6 101.6 20.7 75.0 4.4 47.7 14.6 7.7 50.7 42.6 109.3 7.4 27.2 115.5 0.2 154.7 138.0 1.1 114.2 153.2 59.2 126.5 277.6 8.1 1.6 1.7 144.0 2.1 0.9 74.2 30.1 34.5 24.7 92.0 4.6 0.1 124.5 71.5 0.3 1.7 116.3 29.7 74.7 12.1 31.6 154.8 40.7 78.1 0.3 162.9 0.2 0.1 0.7 77.0 83.1 42.0 0.2 108.4 0.5 13.6 49.0 9.8 158.3 2.7 0.0 89.8 72.6 36.5 0.2 128.2 83.8 78.1 1.0 0.2 9.2 3.8 0.1 42.9 0.1 46.2 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 4.1 0.0 0.1 48.9 84.1 75.3 64.1 51.2 56.9 72.8 77.4 69.7 51.9 75.0 109.3 7.6 41.7 24.8 6.2 0.6 25.1 76.1 111.5 27.3 1.4 32.4 104.5 14.1 72.9 61.0 46.0 0.0 8.1 0.7 109.2 5.9 81.0 18.2 14.7 48.5 7.8 97.9 2.7 0.6 66.4 7.3 127.2 40.8 12.1 3.8 87.8 29.6 13.0 5.7 0.0 0.3 145.7 40.7 0.6 15.9 14.9 120.5 2.0 44.4 1.9 0.0 106.3 0.0 3.0 173.0 88.2 97.9 151.6 0.2 68.1 250.9 37.2 54.6 4.8 65.7 22.1 55.5 40.7 27.7 17.1 12.6 7.1 2.4 132.6 166.6 68.6 TRAPPC2 "hYP38334, MIP-2A, SEDL, SEDT, TRS20, ZNF547L" ENSG00000196459 "Trafficking protein particle complex 2" P0DI81 X 13712244-13734635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004665, HPA063308" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Vesicles" Nucleoplasm "CAB004665: AB_425678, HPA063308: AB_2684982" "unprognostic (1.97e-1)" "prognostic favorable (8.09e-4)" "unprognostic (2.13e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "unprognostic (2.70e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-3)" "unprognostic (1.76e-2)" "prognostic favorable (6.35e-4)" "unprognostic (3.50e-2)" "unprognostic (8.24e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (2.36e-1)" "prognostic favorable (7.89e-5)" 6.0 5.7 12.5 6.7 13.4 7.6 6.8 13.1 14.2 10.0 10.7 10.9 6.0 11.0 6.3 8.4 9.4 5.5 5.3 13.3 13.9 7.4 8.2 7.5 12.7 12.1 11.2 11.2 9.2 5.2 7.7 5.3 12.5 8.3 6.4 10.2 7.3 5.1 4.4 7.4 9.6 8.8 10.2 10.3 9.7 3.2 14.9 9.0 7.8 2.7 11.8 8.9 9.9 11.8 9.1 6.2 10.5 26.1 8.0 5.9 3.7 8.5 7.8 6.7 6.9 5.8 11.0 14.8 13.2 6.9 8.8 11.0 13.8 12.4 8.6 15.3 20.4 11.3 16.0 5.2 6.4 15.9 20.8 8.0 7.0 14.7 17.1 13.4 6.3 11.1 15.0 26.3 7.3 16.0 16.0 21.7 10.6 7.2 11.4 15.3 14.3 14.6 10.8 5.5 10.6 13.6 14.5 12.1 11.0 16.3 13.5 10.6 7.9 6.7 6.2 11.4 5.5 13.3 13.8 19.6 6.0 10.5 6.4 19.3 6.0 11.0 18.1 8.4 18.2 13.2 14.3 17.8 5.5 12.8 11.8 16.6 11.7 22.9 6.9 13.0 18.7 11.1 12.5 13.4 13.1 14.2 13.3 13.9 12.1 11.2 12.5 10.2 14.9 11.8 8.9 9.6 6.5 7.8 22.0 15.2 10.0 14.8 9.6 16.5 16.5 13.6 11.0 15.7 14.6 9.2 12.5 14.1 49.8 14.6 21.5 10.0 17.7 17.3 11.0 9.3 12.1 12.4 20.7 13.4 19.9 11.5 14.8 21.2 9.5 16.9 16.8 12.2 11.6 20.2 20.2 14.0 8.2 12.9 14.4 6.1 12.8 13.6 8.8 10.3 12.0 8.8 44.3 31.7 17.3 15.7 18.6 11.3 17.6 9.8 15.4 23.8 8.5 14.5 6.6 8.6 18.5 4.3 4.0 11.3 17.6 17.9 28.8 16.6 13.2 12.5 TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 60.8" "Cell type enhanced" "Detected in many" "Astrocytes: 758.7;Breast glandular cells: 243.2;Oligodendrocyte precursor cells: 280.5;Oligodendrocytes: 294.0" "Cancer enriched" "Detected in many" 8 "breast cancer: 49.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 47.4;SK-BR-3: 78.1;T-47d: 244.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA060380: AB_2684270, HPA071767: AB_2732185" "unprognostic (4.34e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "prognostic favorable (9.42e-4)" "unprognostic (2.23e-3)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (3.02e-1)" "unprognostic (2.17e-2)" "unprognostic (1.93e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-3)" 4.4 3.1 15.5 5.7 14.3 7.6 60.8 10.5 14.7 10.9 10.1 5.9 0.9 9.9 3.4 14.2 5.5 10.0 3.8 17.0 13.5 5.4 2.1 4.7 4.9 32.5 31.5 5.2 1.1 5.3 2.6 2.8 24.2 9.4 2.7 4.1 12.0 8.4 2.6 10.6 2.1 10.6 18.4 4.2 2.7 12.5 27.5 2.4 5.7 3.3 4.0 5.1 14.1 16.3 3.1 0.6 5.9 0.3 5.4 19.8 0.6 4.9 11.3 3.1 5.2 0.5 4.9 2.4 0.0 12.7 2.6 0.1 22.9 4.3 3.5 0.3 6.9 0.1 10.3 0.2 7.2 0.0 0.3 9.5 4.4 8.6 15.8 8.9 2.7 0.3 1.1 37.7 6.0 47.4 0.2 0.0 1.1 1.1 4.8 0.2 0.2 30.0 4.9 0.3 5.2 3.9 2.5 78.1 3.2 2.8 244.8 2.1 0.2 13.7 6.9 4.0 9.7 10.1 0.3 4.5 14.4 0.0 9.2 0.0 4.5 0.0 0.9 1.9 0.9 0.5 1.0 1.0 1.7 0.8 0.9 0.9 0.8 1.0 1.4 0.6 0.5 0.8 15.5 14.3 10.5 14.7 17.0 13.5 32.5 31.5 24.2 18.4 27.5 16.3 10.0 6.4 3.0 758.7 13.3 9.4 20.0 10.3 34.1 9.2 243.2 125.1 4.6 2.8 9.2 18.4 43.8 0.1 18.7 0.1 11.7 2.9 95.0 58.5 35.7 7.5 0.0 5.5 128.3 2.9 0.2 26.8 4.6 63.5 12.7 0.3 3.6 1.1 16.5 0.0 148.2 0.0 8.2 55.2 104.1 163.2 25.1 55.5 21.4 171.4 32.5 10.6 5.2 280.5 294.0 2.7 0.0 28.2 10.1 16.9 0.0 23.7 8.9 35.9 6.6 60.2 28.2 1.8 8.3 73.6 12.5 0.3 25.6 19.5 0.0 11.2 TSHZ1 "NY-CO-33, SDCCAG33, TSH1" ENSG00000179981 "Teashirt zinc finger homeobox 1" Q6ZSZ6 18 75210755-75289950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 84.9;Peritubular cells: 187.3;Theca cells: 83.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 44.4" "Region enriched" "Detected in all" 5 "olfactory bulb: 115.6" "Low region specificity" "Detected in all" HPA006982 Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA006982: AB_1079886" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (4.03e-1)" "unprognostic (5.89e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (1.24e-1)" "unprognostic (4.12e-2)" "unprognostic (9.05e-2)" "unprognostic (5.64e-2)" "unprognostic (1.69e-1)" "unprognostic (3.43e-3)" "unprognostic (1.26e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.42e-3)" 12.0 7.7 16.3 7.1 14.1 3.3 12.1 23.5 21.0 17.4 6.3 18.1 13.8 11.4 9.3 10.0 15.9 10.4 10.9 17.0 10.4 12.1 8.2 8.0 7.3 18.8 11.5 35.4 7.2 9.2 9.7 29.7 19.3 8.9 9.3 7.9 12.5 11.1 9.2 10.6 13.7 9.3 20.1 9.4 8.8 6.3 15.5 12.3 8.2 6.4 5.3 10.9 11.0 14.1 5.4 7.0 2.2 12.8 18.8 8.9 2.2 24.2 22.6 4.0 7.4 3.2 12.9 10.8 3.0 21.9 4.5 4.8 2.9 6.9 1.4 44.4 23.2 8.3 14.5 4.3 4.9 20.0 9.4 9.1 7.2 3.3 6.5 6.2 10.1 12.5 4.7 19.1 6.6 5.2 14.3 11.4 0.9 6.3 7.6 12.9 6.6 12.9 7.6 3.9 15.9 12.1 6.8 8.8 6.8 0.8 2.0 10.4 7.6 8.7 5.9 6.0 3.9 6.2 15.9 8.7 8.6 16.6 8.1 0.0 0.5 0.5 2.1 0.2 1.4 0.4 1.0 1.8 0.8 0.6 1.5 2.2 0.3 1.5 0.2 0.8 0.4 0.7 16.3 14.1 23.5 21.0 17.0 10.4 18.8 11.5 19.3 20.1 15.5 14.1 60.2 12.8 14.0 34.3 7.1 17.0 5.6 4.8 27.9 40.8 12.2 12.6 24.4 25.8 7.9 3.7 2.1 4.6 25.6 25.4 3.9 7.5 1.2 12.5 33.9 34.4 16.9 6.9 24.9 10.0 2.2 28.8 4.6 18.2 7.0 22.5 21.0 20.5 6.4 11.8 27.7 15.0 10.2 10.8 30.9 5.9 64.7 14.3 8.8 30.0 11.2 17.9 24.7 84.9 21.3 2.9 14.7 187.3 10.6 7.3 29.7 18.4 9.1 12.1 26.3 21.3 12.2 1.4 4.8 33.1 13.2 3.6 18.2 83.2 17.9 5.4 TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.7;Inhibitory neurons: 5.7;Late spermatids: 10.6;Oligodendrocyte precursor cells: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.2;HSkMC: 22.8;NTERA-2: 18.2;SCLC-21H: 9.7;SH-SY5Y: 18.6;SuSa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" 2.5 2.1 5.5 7.5 5.1 0.0 1.9 9.3 5.0 6.5 0.8 25.9 3.9 1.7 5.8 3.5 1.9 7.1 6.5 5.0 3.9 1.0 0.7 3.4 2.2 4.5 5.7 0.8 1.1 0.1 1.0 0.7 3.7 4.1 8.8 1.4 2.4 4.8 0.4 5.6 9.6 6.4 2.3 2.4 3.8 1.0 6.3 0.8 3.1 1.2 4.1 4.5 3.6 4.8 0.0 0.3 25.2 0.0 0.1 0.3 0.2 0.3 0.8 0.0 0.0 0.0 0.8 0.0 1.4 2.2 0.1 0.6 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.1 22.8 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 18.2 0.0 0.2 0.1 0.1 0.5 0.0 0.1 9.7 18.6 0.2 0.0 0.1 11.2 0.0 0.0 0.0 0.1 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.1 9.3 5.0 5.0 3.9 4.5 5.7 3.7 2.3 6.3 4.8 0.6 0.0 0.0 3.6 0.0 0.8 0.0 0.0 0.0 1.7 0.1 0.0 2.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.5 2.4 3.3 0.0 0.0 1.5 0.0 0.0 4.3 0.0 0.4 0.0 0.2 5.7 0.2 0.1 0.0 5.7 0.0 0.0 0.0 1.7 10.6 4.7 0.2 1.8 1.0 0.0 3.6 0.0 27.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 0.5 0.0 0.3 1.1 0.2 0.5 0.1 1.1 0.0 0.2 0.1 0.0 0.1 TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.8;Ductal cells: 125.2;Exocrine glandular cells: 189.3;Pancreatic endocrine cells: 193.4;Paneth cells: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 154.7;EFO-21: 211.3;MCF7: 168.0;OE19: 153.2;PC-3: 266.8;SK-BR-3: 134.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: AB_10967927, HPA071160: " "unprognostic (2.03e-1)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (1.48e-2)" "unprognostic (9.44e-3)" "unprognostic (6.81e-3)" "prognostic unfavorable (8.00e-4)" "unprognostic (2.23e-1)" "unprognostic (3.65e-1)" "unprognostic (2.76e-1)" "unprognostic (8.22e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (8.49e-2)" "unprognostic (4.66e-2)" "unprognostic (6.34e-2)" "unprognostic (3.78e-3)" 70.1 5.3 22.8 15.3 37.6 1.0 61.0 35.0 34.1 16.4 14.9 62.5 38.8 32.6 8.5 10.8 24.6 27.4 16.9 23.6 25.4 25.9 4.6 34.4 8.7 36.9 33.4 3.4 20.0 3.2 6.6 28.1 33.7 34.5 39.4 3.1 26.6 24.7 17.9 10.6 38.8 31.3 30.0 26.7 75.3 9.5 34.5 3.6 14.5 5.6 7.5 46.0 14.9 62.4 51.3 103.9 2.1 0.3 2.3 0.0 12.0 0.2 1.9 2.6 6.8 45.1 154.7 0.0 211.3 2.3 9.2 101.2 7.2 11.5 3.0 42.1 20.4 2.9 3.5 10.0 1.1 0.1 1.8 2.2 3.1 1.4 1.5 7.5 39.4 20.5 1.1 0.0 1.2 168.0 0.6 0.9 2.6 153.2 266.8 4.0 2.1 2.0 29.7 92.9 34.5 13.2 0.6 134.8 17.9 17.3 59.3 2.2 34.5 0.2 0.8 0.1 17.5 1.2 6.1 1.0 1.1 0.1 0.2 0.0 0.0 0.0 2.3 0.0 19.5 0.0 3.1 2.8 3.3 0.0 1.0 0.2 0.0 0.1 0.0 0.2 1.1 0.5 22.8 37.6 35.0 34.1 23.6 25.4 36.9 33.4 33.7 30.0 34.5 62.4 108.8 32.1 6.9 4.9 1.5 3.6 10.9 59.6 2.2 2.9 45.1 15.6 1.7 31.5 29.5 29.5 6.2 2.0 1.6 125.8 3.9 125.2 27.9 25.5 3.8 48.4 40.2 8.0 1.7 189.3 11.9 8.2 71.4 36.6 1.3 2.5 10.4 0.1 25.3 1.7 1.0 106.7 36.7 8.5 16.1 6.6 0.6 9.8 28.4 15.0 15.6 44.7 0.0 11.1 75.3 193.4 120.9 0.0 0.2 50.4 68.3 1.8 27.6 1.5 13.1 39.7 26.8 4.3 18.5 2.9 3.1 3.0 3.9 7.5 66.3 29.6 TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1313.3" "Cell type enhanced" "Detected in all" "Ductal cells: 1162.0;Respiratory ciliated cells: 1173.3;Smooth muscle cells: 1005.3" "Cancer enriched" "Detected in all" 9 "glioma: 942.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1660.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 3100.7;SCLC-21H: 1983.9" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Microtubules "CAB008686: AB_1624202, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.77e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-1)" "unprognostic (1.15e-2)" "unprognostic (2.56e-2)" "unprognostic (2.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (9.79e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.07e-2)" "unprognostic (4.27e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-3)" 150.3 133.5 803.3 166.9 990.4 152.0 179.7 1083.4 882.6 185.8 692.7 466.4 54.4 406.3 166.6 140.0 342.0 193.1 156.5 784.4 1066.9 64.9 21.1 214.3 71.7 1209.8 1002.4 172.8 53.5 79.1 163.4 123.9 1136.6 173.4 126.5 259.7 104.7 267.3 37.4 107.9 125.9 865.4 1083.5 84.7 135.6 69.0 987.8 162.7 39.7 94.1 55.9 210.1 117.1 1313.3 3.2 154.4 3100.7 419.3 263.1 613.9 10.5 286.4 325.6 163.2 390.4 9.4 54.8 120.7 322.4 824.7 304.0 6.4 388.0 97.3 120.3 97.0 138.1 41.5 27.6 34.4 54.1 70.2 3.2 359.5 33.8 325.0 31.8 627.1 945.9 237.2 45.0 124.5 888.7 70.3 276.5 59.2 335.0 3.6 112.5 225.4 232.3 14.1 718.9 13.8 1983.9 1150.3 79.1 4.5 106.0 449.9 210.4 97.3 929.1 178.6 108.5 21.2 80.5 41.5 126.9 234.2 93.8 117.2 191.6 503.5 260.5 824.7 159.0 554.9 118.1 158.2 140.0 146.7 314.0 166.9 134.2 125.2 1660.9 89.9 812.8 101.1 172.8 495.5 803.3 990.4 1083.4 882.6 784.4 1066.9 1209.8 1002.4 1136.6 1083.5 987.8 1313.3 296.9 230.8 181.5 49.9 220.8 87.2 250.6 179.3 59.7 233.0 140.0 291.6 187.9 25.8 148.1 64.4 77.2 10.5 202.9 4.5 25.4 1162.0 10.0 414.9 413.6 334.2 785.8 48.0 78.2 16.2 12.8 391.5 63.2 102.4 547.9 695.0 165.6 2.8 452.0 249.0 60.6 15.5 329.6 80.7 277.6 20.7 193.6 204.2 183.2 37.5 616.6 788.9 77.2 73.4 432.6 333.3 12.8 142.6 32.5 60.4 1.5 73.3 1173.3 349.6 164.3 542.7 1005.3 15.4 31.2 20.9 99.3 15.9 266.5 40.6 12.4 95.7 UCP1 "SLC25A7, UCP" ENSG00000109424 "Uncoupling protein 1" P25874 4 140559431-140568961 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "adrenal gland: 2.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Syncytiotrophoblasts: 2.3" "Cancer enhanced" "Detected in single" "breast cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BEWO: 4.7;HAP1: 3.3;JURKAT: 1.1" "Not detected" "Not detected" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (5.08e-3)" "unprognostic (4.44e-1)" "unprognostic (2.65e-2)" "unprognostic (2.30e-1)" "unprognostic (7.17e-2)" "unprognostic (6.08e-2)" "unprognostic (3.98e-2)" "unprognostic (1.85e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (4.45e-2)" "unprognostic (2.29e-1)" "unprognostic (1.40e-1)" "unprognostic (4.58e-2)" 0.9 2.7 0.0 0.0 0.1 0.0 0.6 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.8 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 2.3 0.0 0.0 0.1 0.0 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 WASF2 "SCAR2, WAVE2" ENSG00000158195 "WASP family member 2" Q9Y6W5 1 27404230-27490167 "Predicted intracellular proteins" "Host-virus interaction" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022632, HPA045288" Enhanced Approved "Plasma membrane,Cytosol" NA NA 84000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" Cytosol "CAB022632: , HPA045288: AB_2679287" "unprognostic (9.58e-2)" "unprognostic (8.93e-2)" "unprognostic (6.28e-2)" "unprognostic (1.02e-1)" "unprognostic (4.40e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (5.29e-8)" "unprognostic (3.94e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (7.60e-3)" "unprognostic (1.10e-1)" "unprognostic (9.15e-3)" "unprognostic (2.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.47e-1)" "unprognostic (8.26e-2)" 55.2 34.1 37.9 44.1 48.1 59.8 45.8 42.3 36.3 41.3 29.5 49.4 27.5 53.8 21.6 89.8 46.3 31.1 32.9 33.4 39.5 28.4 14.9 45.7 48.1 58.9 49.0 63.5 35.2 31.0 17.0 52.3 53.6 33.1 39.3 9.1 38.3 41.9 18.4 56.7 42.3 51.9 48.2 47.6 40.3 36.8 48.4 54.6 35.5 27.8 52.3 47.8 39.9 50.6 75.4 35.3 80.3 73.4 57.1 74.3 46.5 59.9 55.5 64.7 57.9 30.8 79.2 52.1 56.6 94.4 44.1 58.8 65.5 98.4 77.1 73.3 41.1 113.5 60.5 36.7 76.9 91.9 62.8 68.5 105.1 70.7 130.8 70.0 82.3 56.8 92.3 26.3 89.0 27.1 68.7 42.1 64.9 38.3 53.7 141.8 98.5 53.3 46.3 42.0 39.9 43.8 104.6 46.3 78.3 48.6 38.7 55.1 109.1 53.4 54.8 112.1 47.8 53.6 76.0 67.7 63.0 111.2 61.3 50.0 65.4 54.7 33.3 79.8 27.2 37.8 26.3 23.5 41.7 46.6 26.9 21.2 100.7 24.4 112.7 60.5 28.8 58.6 37.9 48.1 42.3 36.3 33.4 39.5 58.9 49.0 53.6 48.2 48.4 50.6 243.0 67.3 57.5 58.1 112.7 148.1 221.8 245.9 104.2 24.4 143.0 201.9 39.6 75.8 144.1 90.1 14.6 219.2 145.1 147.0 62.6 111.0 51.4 86.6 167.7 194.8 108.5 195.1 19.1 101.7 118.9 157.9 85.1 174.2 58.9 77.7 163.5 48.4 151.2 20.2 12.8 101.9 93.6 250.4 129.2 75.9 165.0 162.7 76.5 93.7 207.6 61.2 142.2 29.1 67.1 164.9 131.8 182.4 74.2 281.7 139.1 50.7 104.4 19.2 138.1 206.1 180.6 120.7 118.1 216.3 194.5 143.5 104.5 79.3 120.3 372.5 WNT7A Wnt-7a ENSG00000154764 "Wnt family member 7A" O00755 3 13816258-13880071 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;gallbladder: 2.3;placenta: 2.7" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 68.7;Extravillous trophoblasts: 147.5;Pancreatic endocrine cells: 98.8;Syncytiotrophoblasts: 185.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.2;ovarian cancer: 11.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 1.7;naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cell line enhanced" "Detected in some" "BEWO: 59.8;EFO-21: 56.0;PC-3: 19.9;RPTEC TERT1: 100.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015719, CAB025894" Approved "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB025894: , HPA015719: AB_1858856" "unprognostic (1.26e-2)" "unprognostic (4.60e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (3.02e-1)" "unprognostic (1.14e-3)" "unprognostic (2.49e-1)" "unprognostic (3.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (7.89e-2)" "unprognostic (3.78e-2)" "unprognostic (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (3.74e-1)" "unprognostic (8.88e-3)" 0.0 0.0 3.6 0.1 3.1 0.1 0.0 1.0 3.7 0.2 0.3 0.0 0.0 1.1 0.2 0.4 0.1 2.3 0.0 2.4 2.1 0.2 0.0 2.0 0.2 5.1 1.9 0.0 0.1 0.0 0.0 2.7 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.0 3.4 1.3 0.0 1.3 2.5 0.0 0.0 0.0 0.1 0.3 0.1 2.8 8.6 0.0 0.8 0.0 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 7.6 0.0 56.0 0.0 0.1 11.2 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 1.7 100.3 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.6 3.1 1.0 3.7 2.4 2.1 5.1 1.9 2.5 3.4 2.5 2.8 0.0 12.8 0.0 8.5 0.0 5.9 2.8 2.6 0.0 0.0 0.0 0.0 0.7 8.6 1.4 0.0 0.0 68.7 0.0 0.0 0.0 13.8 17.3 14.5 0.4 0.6 0.0 0.0 4.0 9.1 147.5 0.4 0.0 17.9 0.0 0.0 0.0 0.0 7.4 0.0 2.4 0.0 0.0 0.0 0.0 5.6 0.0 0.1 0.0 1.0 0.0 0.0 0.0 4.5 0.3 98.8 0.0 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.2 6.0 2.3 0.0 1.3 185.7 1.5 0.0 0.0 6.0 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 YWHAQ "14-3-3, HS1" ENSG00000134308 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta" P27348 2 9583967-9630997 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007925, CAB010286" Approved Supported Nucleoplasm,Cytosol NA NA 49000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB010286: AB_2218221, HPA007925: AB_1844340" "unprognostic (2.65e-2)" "unprognostic (3.99e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (1.53e-1)" "unprognostic (5.78e-3)" "prognostic unfavorable (9.83e-6)" "unprognostic (4.90e-3)" "unprognostic (2.98e-2)" "unprognostic (5.51e-2)" "unprognostic (6.18e-2)" "unprognostic (1.45e-1)" "unprognostic (2.95e-2)" "unprognostic (6.74e-2)" "unprognostic (9.75e-2)" "unprognostic (1.63e-1)" "unprognostic (4.39e-3)" 144.6 141.0 190.8 106.1 223.2 178.4 153.6 216.5 239.1 177.0 149.4 161.2 119.4 184.3 141.6 187.3 136.5 122.6 218.7 205.1 229.7 140.0 116.3 119.3 132.0 218.6 203.8 163.2 201.5 131.9 112.9 123.2 212.4 161.1 133.0 143.6 120.2 140.2 53.5 121.5 116.2 177.4 203.9 89.8 127.5 144.6 205.7 148.2 137.6 62.1 141.1 144.4 161.8 280.5 316.1 465.2 412.0 400.3 316.6 434.5 385.7 421.6 412.3 432.5 360.2 352.9 269.3 404.4 214.0 608.5 451.3 288.5 462.8 459.7 553.6 1003.0 374.8 378.8 268.9 379.9 241.1 369.1 219.7 295.8 264.5 473.6 305.9 394.9 493.5 285.6 378.5 236.8 539.3 219.3 658.2 374.4 700.7 351.9 527.5 473.0 533.3 497.4 478.8 276.9 390.1 659.9 384.1 392.2 317.3 343.8 244.4 187.0 453.9 539.6 380.7 473.4 654.4 239.3 351.4 526.6 461.8 378.9 458.8 99.5 102.7 120.5 207.8 137.8 255.6 151.9 192.8 223.5 144.2 147.8 103.6 170.1 31.1 252.0 137.0 73.1 208.4 344.1 190.8 223.2 216.5 239.1 205.1 229.7 218.6 203.8 212.4 203.9 205.7 280.5 186.6 51.3 67.3 26.1 144.0 316.7 366.5 339.0 143.4 201.4 198.4 153.7 82.6 90.1 143.4 136.1 27.1 261.6 189.9 209.9 416.7 371.5 281.9 132.9 175.8 191.0 187.1 179.2 57.3 283.7 615.3 242.0 115.2 131.6 125.0 152.5 84.9 97.9 215.3 572.0 45.1 129.2 270.6 111.9 228.3 360.5 174.0 132.3 295.3 30.0 195.0 229.2 155.5 39.7 186.6 261.2 150.9 250.5 187.9 323.7 135.9 278.8 111.7 105.8 197.2 191.5 312.7 432.2 205.8 252.1 355.3 238.6 217.7 252.9 186.5 457.3 ZC4H2 "HCA127, KIAA1166, MCS, MRXS4, WWS" ENSG00000126970 "Zinc finger C4H2-type containing" Q9NQZ6 X 64915802-65034713 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 37.4;Inhibitory neurons: 39.4;Oligodendrocyte precursor cells: 58.3;Oligodendrocytes: 59.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 37.3;REH: 29.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049584 Approved Approved Vesicles,Microtubules NA NA "Cluster 30: Non-specific - Translation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Microtubules" "HPA049584: AB_2680825" "unprognostic (9.55e-3)" "unprognostic (1.03e-1)" "unprognostic (4.40e-1)" "unprognostic (1.56e-1)" "unprognostic (7.29e-3)" "unprognostic (9.71e-2)" "unprognostic (1.64e-3)" "unprognostic (9.72e-2)" "unprognostic (2.98e-1)" "unprognostic (3.34e-1)" "unprognostic (2.31e-2)" "unprognostic (6.44e-2)" "unprognostic (1.84e-3)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.51e-5)" "unprognostic (5.34e-2)" 4.5 6.3 7.1 2.5 7.2 2.5 4.1 7.0 8.0 5.9 6.9 9.6 3.9 7.0 4.3 3.4 6.1 3.7 5.7 7.0 7.9 5.4 5.3 3.4 2.8 7.5 7.6 7.2 3.6 11.8 8.6 0.9 7.6 5.3 4.4 5.0 4.3 5.8 1.8 3.8 5.3 7.9 7.2 4.2 6.3 1.0 7.2 8.0 5.4 1.9 2.6 5.3 4.1 7.3 0.0 1.5 23.4 11.0 0.2 0.0 3.7 4.4 9.3 6.3 11.5 2.2 8.8 4.4 2.5 3.9 0.0 0.1 10.4 4.0 6.2 0.0 9.5 7.4 3.3 3.2 1.4 6.8 2.2 4.7 3.3 2.9 6.5 9.5 11.5 25.1 2.4 9.9 7.5 0.0 20.2 0.0 37.3 4.2 10.2 29.8 11.3 0.2 6.5 0.0 0.0 16.8 0.0 0.1 0.9 13.9 2.0 1.3 7.2 3.2 6.7 0.3 0.0 1.8 0.2 14.9 9.9 6.2 0.0 0.0 0.7 0.0 1.7 1.0 3.0 2.6 2.4 2.4 0.9 1.9 3.9 2.4 0.0 2.1 0.2 2.4 1.2 1.4 7.1 7.2 7.0 8.0 7.0 7.9 7.5 7.6 7.6 7.2 7.2 7.3 2.9 3.2 0.0 20.5 6.6 0.6 2.0 1.9 1.8 3.8 1.5 2.2 4.0 4.3 1.8 1.8 4.2 0.1 1.2 1.9 1.9 7.7 0.6 1.7 3.0 4.5 3.6 3.4 37.4 5.7 0.8 4.0 3.6 0.5 2.5 5.2 5.0 4.1 1.1 0.0 39.4 1.9 8.2 0.9 0.0 0.8 7.2 0.8 0.0 22.5 0.5 5.1 2.1 58.3 59.0 4.7 2.2 8.6 1.5 1.0 3.8 5.6 0.6 1.6 13.1 2.8 4.1 0.6 0.5 1.8 0.6 0.0 1.9 4.5 3.3 1.0 ZCCHC12 "FLJ16123, PNMA7A, SIZN, SIZN1" ENSG00000174460 "Zinc finger CCHC-type containing 12" Q6PEW1 X 118823824-118826968 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 281.2;endometrium 1: 101.5;fallopian tube: 132.2;smooth muscle: 141.6" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 4.6;Spermatogonia: 5.6" "Cancer enriched" "Detected in many" 76 "thyroid cancer: 256.3" "Group enriched" "Detected in all" 5 "hypothalamus: 281.2;thalamus: 156.5" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 7 "T-cells: 1.2" "Cell line enhanced" "Detected in some" "HAP1: 3.9;HEK 293: 10.1;NTERA-2: 3.2;SH-SY5Y: 2.5;SuSa: 2.0" "HPA031016, HPA034940" Uncertain Approved "Nuclear bodies" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies" "HPA031016: AB_2673698, HPA034940: AB_10671098" "unprognostic (1.29e-1)" "unprognostic (7.48e-3)" "unprognostic (1.96e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-2)" "unprognostic (1.28e-1)" "unprognostic (5.66e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (3.44e-1)" "unprognostic (8.36e-3)" "unprognostic (5.34e-4)" "unprognostic (9.18e-13)" "unprognostic (4.14e-3)" "unprognostic (1.63e-1)" "prognostic favorable (3.42e-5)" "unprognostic (1.18e-1)" 0.2 7.7 35.8 0.8 24.5 0.0 0.4 19.4 30.0 32.1 0.4 1.2 0.3 101.5 8.7 0.0 132.2 0.4 0.1 22.2 281.2 0.1 0.1 0.5 0.6 26.5 48.1 3.1 0.1 0.0 26.9 0.0 37.8 0.4 0.4 4.2 0.0 0.5 0.0 0.0 0.9 141.6 12.4 0.2 0.9 0.5 156.5 0.6 3.1 0.0 0.7 0.0 6.1 5.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.3 0.0 0.2 0.0 3.9 0.0 0.1 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.5 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 35.8 24.5 19.4 30.0 22.2 281.2 26.5 48.1 37.8 12.4 156.5 5.5 0.2 0.0 0.0 0.7 0.6 0.0 0.1 0.0 0.6 0.9 0.2 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 1.2 0.2 1.2 0.0 0.4 0.0 0.0 0.3 0.0 0.9 0.0 0.5 0.0 0.0 0.1 0.0 4.6 0.5 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 1.6 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.5 1.4 1.2 5.6 0.1 0.1 0.0 0.7 0.5 0.1 0.0 ZFYVE21 "MGC2550, ZF21" ENSG00000100711 "Zinc finger FYVE-type containing 21" Q9BQ24 14 103715730-103733668 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 165.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055721 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA055721: AB_2682896" "unprognostic (1.10e-2)" "unprognostic (3.35e-1)" "unprognostic (8.89e-2)" "unprognostic (7.54e-3)" "unprognostic (1.96e-1)" "unprognostic (8.32e-2)" "unprognostic (4.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.04e-2)" "unprognostic (5.11e-3)" "unprognostic (5.02e-2)" "unprognostic (9.13e-2)" "prognostic favorable (2.58e-6)" "unprognostic (2.30e-3)" "unprognostic (1.71e-1)" "unprognostic (7.18e-2)" "unprognostic (2.06e-1)" 57.4 28.9 117.0 14.2 121.0 11.9 54.0 115.6 143.1 69.3 113.2 52.3 18.2 70.8 50.3 68.4 71.8 28.4 51.6 112.8 116.0 37.0 34.7 31.6 16.5 121.3 114.4 56.1 26.7 34.1 32.0 30.1 118.0 41.0 25.7 15.2 61.5 53.3 22.0 73.2 31.0 45.6 123.6 28.1 44.9 35.5 120.0 19.3 50.3 29.9 17.5 65.1 67.8 127.4 27.1 34.1 29.1 26.7 76.9 61.6 48.2 49.8 35.2 41.5 36.2 40.2 34.3 6.0 31.5 53.2 29.9 45.4 25.3 59.4 37.3 11.5 30.9 33.5 23.0 55.3 60.8 8.6 21.4 42.1 61.6 18.4 29.8 37.4 51.0 19.6 13.0 11.4 29.9 165.5 23.3 26.8 13.4 41.3 47.9 12.6 21.6 9.2 81.5 95.5 16.6 11.5 35.2 44.3 26.2 32.2 56.6 22.3 44.7 20.1 16.3 68.4 25.6 12.8 13.8 9.2 22.7 18.7 19.5 28.3 36.2 42.1 20.0 57.6 19.8 18.1 18.7 20.1 23.9 24.7 19.4 18.5 29.6 16.3 47.8 19.4 21.7 24.6 117.0 121.0 115.6 143.1 112.8 116.0 121.3 114.4 118.0 123.6 120.0 127.4 68.0 19.2 23.9 61.7 9.5 45.5 83.5 161.9 59.2 27.8 58.8 68.6 36.0 41.5 83.1 80.9 33.3 115.7 20.9 33.6 121.3 56.4 14.2 25.3 54.7 71.0 19.3 76.2 30.9 54.5 40.0 65.3 12.2 30.3 19.7 22.0 66.4 26.9 55.4 20.2 11.8 34.2 81.4 22.6 29.5 23.0 109.6 28.4 103.2 19.7 32.3 91.6 24.7 11.6 21.8 79.3 51.9 197.1 7.4 87.7 31.5 98.9 47.1 29.6 65.7 57.2 60.7 46.3 78.4 50.9 60.2 101.5 13.4 36.3 32.4 81.9 ZMIZ1 "FLJ13541, hZIMP10, KIAA1224, MIZ, RAI17, RP11-519K18.1, Zimp10" ENSG00000108175 "Zinc finger MIZ-type containing 1" Q9ULJ6 10 79068966-79316519 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 259.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 176.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045144, HPA071156" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA045144: AB_10962360, HPA071156: " "unprognostic (4.09e-3)" "unprognostic (1.72e-1)" "unprognostic (2.63e-1)" "unprognostic (5.59e-2)" "unprognostic (2.02e-1)" "unprognostic (2.86e-2)" "unprognostic (3.64e-3)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (1.16e-1)" "unprognostic (3.13e-2)" "unprognostic (7.90e-2)" "prognostic favorable (3.64e-7)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (8.22e-2)" "unprognostic (1.34e-2)" 34.0 24.4 24.5 19.2 27.1 26.6 27.7 25.1 30.1 44.7 5.2 28.1 19.2 51.5 18.8 37.5 26.5 25.9 31.8 25.8 27.5 17.2 8.7 26.5 17.5 34.5 36.0 48.5 23.3 19.2 12.5 21.7 29.9 19.5 14.5 14.6 28.4 28.8 34.6 33.7 22.2 26.9 27.2 44.8 27.6 4.5 33.9 16.4 37.3 17.0 18.2 28.4 31.0 23.1 24.0 29.3 54.8 23.6 55.8 16.0 19.1 22.4 40.2 15.6 8.8 8.7 10.8 12.2 17.8 52.8 40.9 33.0 9.2 16.6 8.4 26.5 5.1 43.5 11.1 25.9 39.2 24.3 88.1 21.0 18.2 22.3 15.9 98.4 25.3 10.2 16.9 62.9 13.3 45.4 24.4 37.6 16.2 13.8 44.0 107.5 10.3 12.3 11.6 20.0 56.8 82.8 14.8 176.2 46.8 19.4 56.5 23.4 35.5 58.7 23.5 29.9 29.2 11.5 21.9 0.2 77.0 42.7 11.5 1.3 2.1 1.6 1.2 3.6 0.8 0.5 0.8 0.7 2.6 0.2 0.3 0.6 3.0 3.4 3.0 2.5 1.0 1.2 24.5 27.1 25.1 30.1 25.8 27.5 34.5 36.0 29.9 27.2 33.9 23.1 49.3 38.5 26.0 64.9 14.5 22.8 8.4 14.9 15.4 49.8 27.1 18.0 54.4 20.0 15.8 16.5 0.0 7.1 14.7 39.1 7.9 22.1 47.2 17.9 75.3 49.9 13.8 25.7 23.1 24.1 5.6 36.2 38.7 33.2 50.6 16.8 56.4 9.6 37.9 63.9 16.4 14.5 14.2 34.9 86.0 259.7 28.3 52.4 24.9 46.9 27.2 12.9 4.1 92.5 45.5 19.3 22.5 23.7 14.2 13.0 19.7 8.1 14.7 3.4 19.7 24.7 32.6 1.8 3.2 40.8 23.7 3.6 12.1 14.3 14.8 12.7 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0